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73 Reviews — Review Commons — Cancer Biology

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CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival
Lier, S., Lund, S. O., Lipsa, A., Frauenknecht, K. B. M., Rein, I. D., Jain, P., Lang, A., Lang, E., Meyer, N., Datta, A., Anand, S., Nesse, G., Forstrom, R. J., Klungland, A., Rinholm, J. E., Boe, S. O., Anand, A., Pollard, S. M., Niclou, S. P., Lerdrup, M., Pandey, D. P.
10.1101/2023.07.14.548985 — Posted: 2023-07-17 — Discussion: 2023-12-18  Review Commons
Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
Daum, A.-K., Schlicker, L., Schneider, M. A., Muley, T., Klingmüller, U., Schulze, A., Thomas, M., Christopoulos, P., Sültmann, H.
10.1101/2023.08.08.552439 — Posted: 2023-08-11 — Discussion: 2023-11-10  Review Commons
Lipid Droplets Fuel Small Extracellular Vesicle Biogenesis
Genard, G., Tirinato, L., Pagliari, F., Da Silva, J., Giammona, A., Alquraish, F., Bordas, M., Marafioti, M. G., Di Franco, S., Jansen, J., Garcia-Calderon, D., Hanley, R., Nistico, C., Fukasawa, Y., Mueller, T., Krijgsveld, J., Todaro, M., Costanzo, F. S., Stassi, G., Nessling, M., Richter, K., Maass, K., Liberale, C., Seco, J.
10.1101/2022.10.24.513202 — Posted: 2022-10-24 — Discussion: 2023-08-29  Review Commons
High-content microscopy reveals a morphological signature of bortezomib resistance
Kelley, M. E., Berman, A. Y., Stirling, D. R., Cimini, B. A., Han, Y., Singh, S., Carpenter, A. E., Kapoor, T. M., Way, G. P.
10.1101/2023.05.02.539137 — Posted: 2023-05-02 — Discussion: 2023-08-26  Review Commons
MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis
DeRollo, R. E., Cazarin, J., Ahmad Shahidan, S. N. A. B., Burchett, J. B., Mwangi, D., Krishnaiah, S., Hsieh, A. L., Walton, Z. E., Brooks, R., Mello, S. S., Weljie, A. M., Dang, C. V., Altman, B. J.
10.1101/2023.01.03.522637 — Posted: 2023-01-03 — Discussion: 2023-08-25  Review Commons
Identifying targetable metabolic dependencies across colorectal cancer progression
Legge, D. N., Holt, A. K., Bull, C. J., Collard, T. J., Kollareddy, M., Bellamy, J., Groves, S., Ma, E. H., Hazelwood, E., Qualtrough, D., Amulic, B., Malik, K. N., Williams, A. C., Jones, N., Vincent, E. E.
10.1101/2022.03.23.485483 — Posted: 2022-03-23 — Discussion: 2023-08-23  Review Commons
The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer
Pascual-Reguant, L., Tian, T. V., Datta, D., Cianferoni, D., Kourtis, S., Ganez Zapater, A., Cannata, C., Serra Camprubi, Q., Espinar, L., Guirola, M., Querol, J., Miro Canturri, A., Arribas, J., Serrano, L., Peiro, S., Sdelci, S.
10.1101/2022.05.27.493725 — Posted: 2022-05-28 — Discussion: 2023-08-03  Review Commons
Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma
Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J. P., Geudens, I., Stanchi, F., Ligon, K. L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F., Gerhardt, H.
10.1101/2023.04.27.538517 — Posted: 2023-05-01 — Discussion: 2023-06-09  Review Commons
Mesenchymal stem cell models reveal critical role of Myc as early molecular event in osteosarcomagenesis
Akkawi, R., Monin, J., Diment, J., Stein, G. S., Aqeilan, R. I.
10.1101/2023.03.14.532523 — Posted: 2023-03-15 — Discussion: 2023-03-27  Review Commons
The extracellular matrix promotes breast cancer cell growth under amino acid starvation by promoting tyrosine catabolism
Nazemi, M., Yanes, B., Llanses Martinez, M., Walker, H., Bard, F., Rainero, E.
10.1101/2021.06.09.447520 — Posted: 2021-06-09 — Discussion: 2023-03-10  Review Commons

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