bioRxiv/medRxiv TRiP Review Activity

75 Reviews — Review Commons — Cancer Biology

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GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation

Anastasiou, D., Grimm, F., Asuaje, A., Jain, A., Silva dos Santos, M., Kleinjung, J., Nunes, P. M., Gehrig, S., Fets, L., MacRae, J.

10.1101/2023.09.06.556522 — Posted: 2023-09-07 — Discussion: 2023-12-21 Review Commons

Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

Zhang, T., Li, S., Tan, A. Y., Na, J., Chen, Z., Damle, P., Chen, X., Choi, S., Mishra, B., Wang, D., Grossman, S. R., Jiang, X., Li, Y., Chen, Y.-T., Xiang, J. Z., Du, N.

10.1101/2023.04.26.538373 — Posted: 2023-04-28 — Discussion: 2023-12-20 Review Commons

CDK12/CDK13 inhibition disrupts a transcriptional program critical for glioblastoma survival

Lier, S., Lund, S. O., Lipsa, A., Frauenknecht, K. B. M., Rein, I. D., Jain, P., Lang, A., Lang, E., Meyer, N., Datta, A., Anand, S., Nesse, G., Forstrom, R. J., Klungland, A., Rinholm, J. E., Boe, S. O., Anand, A., Pollard, S. M., Niclou, S. P., Lerdrup, M., Pandey, D. P.

10.1101/2023.07.14.548985 — Posted: 2023-07-17 — Discussion: 2023-12-18 Review Commons

Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis

Daum, A.-K., Schlicker, L., Schneider, M. A., Muley, T., Klingmüller, U., Schulze, A., Thomas, M., Christopoulos, P., Sültmann, H.

10.1101/2023.08.08.552439 — Posted: 2023-08-11 — Discussion: 2023-11-10 Review Commons

Lipid Droplets Fuel Small Extracellular Vesicle Biogenesis

Genard, G., Tirinato, L., Pagliari, F., Da Silva, J., Giammona, A., Alquraish, F., Bordas, M., Marafioti, M. G., Di Franco, S., Jansen, J., Garcia-Calderon, D., Hanley, R., Nistico, C., Fukasawa, Y., Mueller, T., Krijgsveld, J., Todaro, M., Costanzo, F. S., Stassi, G., Nessling, M., Richter, K., Maass, K., Liberale, C., Seco, J.

10.1101/2022.10.24.513202 — Posted: 2022-10-24 — Discussion: 2023-08-29 Review Commons

High-content microscopy reveals a morphological signature of bortezomib resistance

Kelley, M. E., Berman, A. Y., Stirling, D. R., Cimini, B. A., Han, Y., Singh, S., Carpenter, A. E., Kapoor, T. M., Way, G. P.

10.1101/2023.05.02.539137 — Posted: 2023-05-02 — Discussion: 2023-08-26 Review Commons

MYC disrupts transcriptional and metabolic circadian oscillations in cancer and promotes enhanced biosynthesis

DeRollo, R. E., Cazarin, J., Ahmad Shahidan, S. N. A. B., Burchett, J. B., Mwangi, D., Krishnaiah, S., Hsieh, A. L., Walton, Z. E., Brooks, R., Mello, S. S., Weljie, A. M., Dang, C. V., Altman, B. J.

10.1101/2023.01.03.522637 — Posted: 2023-01-03 — Discussion: 2023-08-25 Review Commons

Identifying targetable metabolic dependencies across colorectal cancer progression

Legge, D. N., Holt, A. K., Bull, C. J., Collard, T. J., Kollareddy, M., Bellamy, J., Groves, S., Ma, E. H., Hazelwood, E., Qualtrough, D., Amulic, B., Malik, K. N., Williams, A. C., Jones, N., Vincent, E. E.

10.1101/2022.03.23.485483 — Posted: 2022-03-23 — Discussion: 2023-08-23 Review Commons

The BRD4S-LOXL2-MED1 interaction at the forefront of cell cycle transcriptional control in triple-negative breast cancer

Pascual-Reguant, L., Tian, T. V., Datta, D., Cianferoni, D., Kourtis, S., Ganez Zapater, A., Cannata, C., Serra Camprubi, Q., Espinar, L., Guirola, M., Querol, J., Miro Canturri, A., Arribas, J., Serrano, L., Peiro, S., Sdelci, S.

10.1101/2022.05.27.493725 — Posted: 2022-05-28 — Discussion: 2023-08-03 Review Commons

Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

Finotto, L., Cole, B., Giese, W., Baumann, E., Claeys, A., Vanmechelen, M., Decraene, B., Derweduwe, M., Dubroja Lakic, N., Shankar, G., Nagathihalli Kantharaju, M., Albrecht, J. P., Geudens, I., Stanchi, F., Ligon, K. L., Boeckx, B., Lambrechts, D., Harrington, K., Van Den Bosch, L., De Vleeschouwer, S., De Smet, F., Gerhardt, H.

10.1101/2023.04.27.538517 — Posted: 2023-05-01 — Discussion: 2023-06-09 Review Commons