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428 Reviews — All Partners — Cancer Biology

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Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth
Wang, Y., Salvucci, O., Ohnuki, H., Tran, A. D., Ha, T., Feng, J.-X., DiPrima, M., Kwak, H., Wang, D., Kruhlak, M., Tosato, G.
10.1101/2020.10.06.327882 — Posted: 2020-10-07 — Discussion: 2021-07-16  EMBO Press
MicroRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi
McNeal, A. S., Belote, R. L., Zeng, H., Barker, K., Torres, R., Shain, A. H., Andtbacka, R. H., Holmen, S. L., Lum, D. H., McCalmont, T., VanBrocklin, M. W., Wei, M. L., Lang, U. E., Judson-Torres, R. L.
10.1101/2020.05.21.109397 — Posted: 2020-05-24 — Discussion: 2021-07-07  eLife
Aneuploid cells activate NF-κB to promote their immune clearance by NK cells
Wang, R. W., Vigano', S., Ben-David, U., Amon, A., Santaguida, S.
10.1101/2020.06.25.172239 — Posted: 2020-06-27 — Discussion: 2021-06-30  EMBO Press
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
Knight, J. R., Vlahov, N., Gay, D. M., Ridgway, R. A., Faller, L., Proud, C., Mallucci, G. R., von der Haar, T., Smales, C. M., Willis, A. E., Sansom, O. J.
10.1101/2021.05.05.442715 — Posted: 2021-05-05 — Discussion: 2021-06-28  eLife
HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
Miyamoto, R., Kanai, A., Okuda, H., Takahashi, S., Matsui, H., Inaba, T., Yokoyama, A.
10.1101/2020.10.20.347765 — Posted: 2020-10-21 — Discussion: 2021-06-22  eLife
Pancreatic Cancer Intrinsic PI3Kα Activity accelerates Metastasis and rewires Macrophage Component
Thibault, B., Ramos-Delgado, F., Pons-Tostivint, E., Therville, N., Cintas, C., Arcucci, S., Cassant-Sourdy, S., Reyes-Castellanos, G., Tosolini, M., Villard, A. V., Cayron, C., Baer, R., Bertrand-Michel, J., Payen, D., Yan, H., Falcomata, C., Muscari, F., Bournet, B., Delord, J.-P., Aksoy, E., Carrier, A., Cordelier, P., Saur, D., Basset, C., Guillermet-Guibert, J.
10.1101/2020.09.23.307884 — Posted: 2020-09-24 — Discussion: 2021-06-08  EMBO Press
Exosome component 1 cleaves single-stranded DNA and sensitizes kidney renal clear cell carcinoma cells to poly(ADP-ribose) polymerase inhibitor
Yang, Q., Xiao, Q., Liu, Q., Wang, L., Wang, N., Wang, K., Song, C.
10.1101/2021.04.18.440347 — Posted: 2021-04-19 — Discussion: 2021-06-03  eLife
KSR1-and ERK-dependent Translational Regulation of the Epithelial-to-Mesenchymal Transition
Rao, C., Frodyma, D. E., Southekal, S., Svoboda, R. A., Black, A. R., Guda, C., Mizutani, T., Clever, H., Johnson, K. R., Fisher, K. W., Lewis, R. E.
10.1101/2021.01.18.427224 — Posted: 2021-01-21 — Discussion: 2021-04-22  eLife
Oxaliplatin Resistance in Colorectal Cancer Enhances TRAIL Sensitivity Via Death Receptor 4 Upregulation and Lipid Raft Localization
Greenlee, J. D., Lopez Cavestany, M., Ortiz-Otero, N., Liu, K., Subramanian, T., Cagir, B., King, M. R.
10.1101/2021.03.05.434100 — Posted: 2021-03-05 — Discussion: 2021-04-21  eLife
USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J., Pinto-Fernandez, A., Turnbull, A. P., Lan, L., Charlton, T. M., Scott, H. C., Damianou, A., Vere, G., Riising, E. M., Da Costa, C., Krajewski, W. W., Guerin, D., Kearns, J., Ioannidis, S., Katz, M., O'Connell, J. C., Moncaut, N., Rosewell, I., Nye, E., Jones, N., Heride, C., Gersch, M., Wu, M., Dinsmore, C. J., Hammonds, T. R., Kim, S., Komander, D., Urbe, S., Clague, M. J., Kessler, B. M., Behrens, A.
10.1101/2020.11.17.377705 — Posted: 2020-11-17 — Discussion: 2021-04-06  eLife

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