bioRxiv/medRxiv TRiP Review Activity

428 Reviews — All Partners — Cancer Biology

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AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in Castrate-Resistant Prostate Cancer

Kim, S., Jamalruddin, M. A. B., Au, C. C., Mukhtar, E., Portella, L., Berger, A., Worroll, D., Rickman, D. S., Nanus, D. M., Giannakakou, P.

10.1101/2021.06.03.446940 — Posted: 2021-06-03 — Discussion: 2021-11-10 eLife

RASSF1C oncogene elicits amoeboid invasion, cancer stemness and invasive EVs via a novel SRC/Rho axis

Tognoli, M. L., Vlahov, N., Steenbeek, S., Grawenda, A. M., Eyres, M., Cano-Rodriguez, D., Scrace, S., Kartsonaki, C., von Kriegsheim, A., Willms, E., Wood, M., Rots, M. G., van Rheenen, J., O'Neill, E., Pankova, D.

10.1101/2021.01.05.425393 — Posted: 2021-01-06 — Discussion: 2021-10-26 EMBO Press

ZHX2 Promotes HIF1α Oncogenic Signaling in Triple-Negative Breast Cancer

Fang, W., Liao, C., Shi, R., Simon, J., Ptacek, T., Zurlo, G., Ye, Y., Han, L., Fan, C., Ortiz, C. L., Lin, H.-R., Manocha, U., Luo, W., Kim, W. Y., Yang, L.-W., Zhang, Q.

10.1101/2021.05.27.445959 — Posted: 2021-05-28 — Discussion: 2021-10-15 eLife

The Pancreatic Tumor Microenvironment Buffers Redox Imbalance Imposed by Disrupted Mitochondrial Metabolism

Kerk, S. A., Lin, L., Myers, A. L., Chen, B., Sajjakulnukit, P., Robinson, A., Thurston, G., Nelson, B. S., Kemp, S. B., Steele, N. G., Hoffman, M. T., Wen, H.-J., Long, D., Ackenhusen, S. E., Ramos, J., Gao, X., Zhang, L., Andren, A., Nwosu, Z. C., Galban, S., Halbrook, C. J., Lombard, D. B., Ying, H., Crawford, H. C., Pasca di Magliano, M., Shah, Y. M., Lyssiotis, C. A.

10.1101/2020.08.07.238766 — Posted: 2020-08-07 — Discussion: 2021-10-13 eLife

HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis

Takahashi, S., Kanai, A., Okuda, H., Miyamoto, R., Kawamura, T., Matsui, H., Inaba, T., Takaori-Kondo, A., Yokoyama, A.

10.1101/2021.01.08.425834 — Posted: 2021-01-08 — Discussion: 2021-08-13 eLife

Zebrafish embryo screen identifies anti-metastasis drugs

Nakayama, J., Tan, L., Goh, B. C., Wang, S., Makinoshima, H., Zhiyuan, G.

10.1101/2021.03.04.434001 — Posted: 2021-03-05 — Discussion: 2021-08-11 eLife

Lipid Droplets and Ferritin Heavy Chain: a Devilish Liaison in Cancer Radioresistance

Tirinato, L., Marafioti, M. G., Pagliari, F., Jansen, J., Aversa, I., Hanley, R., Nistico, C., Garcia-Calderon, D., Genard, G., Guerreiro, J. F., Costanzo, F. S., Seco, J.

10.1101/2021.05.11.443559 — Posted: 2021-05-13 — Discussion: 2021-08-03 Review Commons

A tumor suppressive long noncoding RNA, DRAIC, inhibits protein translation and induces autophagy by activating AMPK

Saha, S., Zhang, Y., Wilson, B., Abounader, R., Dutta, A.

10.1101/2021.06.04.447165 — Posted: 2021-06-04 — Discussion: 2021-08-03 Review Commons

TOP2A substitution enhances topoisomerase activity and causes transcriptional dysfunction in glioblastoma patients

Gielniewski, B., Poleszak, K., Roura, A.-J., Szadkowska, P., Krol, S. K., Guzik, R., Wiechecka, P., Maleszewska, M., Kaza, B., Marchel, A., Czernicki, T., Koziarski, A., Zielinski, G., Styk, A., Kawecki, M., Szczylik, C., Czepko, R., Banach, M., Kaspera, W., Szopa, W., Bujko, M., Czapski, B., Zabek, M., Izycka-Swieszewska, E., Kloc, W., Nauman, P., Wojtas, B., Kaminska, B.

10.1101/2020.06.17.158477 — Posted: 2020-06-18 — Discussion: 2021-07-26 Review Commons

Primary platinum resistance and immune exclusion in ovarian carcinomas with high expression of the homologous recombination mediator RAD51

Hoppe, M. M., Tan, T. Z., Lie, S., Lim, S., Yeong, J. P., Wardyn, J. D., Jaynes, P., Lim, D. G., Pang, B. N., Karnezis, A., Chiu, D., Leung, S., Huntsman, D. G., Sedukhina, A. S., Sato, K., Kaye, S., Choi, H., Patel, N., Brown, R., Pitt, J. J., Tan, D. S., Jeyasekharan, A.

10.1101/2020.06.09.137612 — Posted: 2020-06-09 — Discussion: 2021-07-17 EMBO Press