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428 Reviews — All Partners — Cancer Biology

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Proton export drives the Warburg Effect
Russell, S., Xu, L., Kam, Y., Abrahams, D., Ordway, B., Lopez, A., Bui, M. M., Johnson, J., Epstein, T., Ruiz, E., Lloyd, M., Swietach, P., Verduzco, D., Wojtkowiak, J., Gillies, R.
10.1101/2021.09.20.461019 — Posted: 2021-09-21 — Discussion: 2022-02-02  eLife
The Sec61 translocon is a therapeutic vulnerability in Multiple Myeloma
Domenger, A., Choisy, C., Baron, L., Mayau, V., Deriano, L., Arnulf, B., Bories, J.-C., Dadaglio, G., Demangel, C.
10.1101/2021.09.05.459026 — Posted: 2021-09-06 — Discussion: 2022-01-28  EMBO Press
JAMMIT Analysis Defines 2 Semi-Independent Immune Processes Common to 29 Solid Tumors
Zitello, E., Vo, M., Bowler, S., Chen, S., Wenska, T., Khadka, V., Hoffmann, P., Okimoto, G., Deng, Y.
10.1101/2021.08.31.458339 — Posted: 2021-09-01 — Discussion: 2022-01-09  eLife
The protective effect of aspirin in colorectal carcinogenesis: a multiscale computational study from mutant evolution to age incidence curves
Wang, Y., Boland, C. R., Goel, A., Wodarz, D., Komarova, N.
10.1101/2021.05.11.443671 — Posted: 2021-05-12 — Discussion: 2021-12-24  eLife
Ras/MAPK signalling intensity defines subclonal fitness in a mouse model of primary and metastatic hepatocellular carcinoma
Lozano, A., Souche, F.-R., Ramirez, C., Vegna, S., Desandre, G., Riviere, A., Dardalhon, V., Zine El Aabidine, A., Fort, P., Akkari, L., Hibner, U., Gregoire, D.
10.1101/2021.08.13.456223 — Posted: 2021-08-13 — Discussion: 2021-12-11  Review Commons
Stereo-specific Lasofoxifene Derivatives Reveal the Interplay between Estrogen Receptor Alpha Stability and Antagonistic Activity in ESR1 Mutant Breast Cancer Cells
Hosfield, D. J., Weber, S., Li, N.-S., Suavage, M., Sullivan, E., Nduwke, E., Han, R., Cush, S., Laine, M., Mader, S. C., Greene, G. L., Fanning, S. W.
10.1101/2021.08.27.457901 — Posted: 2021-08-28 — Discussion: 2021-12-01  eLife
Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference
Lynch, A. R., Arp, N. L., Zhou, A. S., Weaver, B. A., Burkard, M. E.
10.1101/2021.04.26.441466 — Posted: 2021-04-27 — Discussion: 2021-12-01  eLife
The unfolded protein response links tumor aneuploidy to local immune dysregulation
Xian, S., Searles, S. T., Sahani, P., Weller, T. C., Jepsen, K., Carter, H., Zanetti, M.
10.1101/2020.11.10.377358 — Posted: 2020-11-11 — Discussion: 2021-11-24  EMBO Press
Type I PRMTs and PRMT5 Inversely Regulate Post-Transcriptional Intron Detention
Maron, M. I., Casill, A. D., Gupta, V., Sidoli, S., Query, C. C., Gamble, M. J., Shechter, D.
10.1101/2021.08.20.457069 — Posted: 2021-08-20 — Discussion: 2021-11-24  eLife
Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Urtatiz, O., Haage, A., Tanentzapf, G., Van Raamsdonk, C. D.
10.1101/2021.07.26.453858 — Posted: 2021-07-26 — Discussion: 2021-11-10  eLife

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