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434 Reviews — eLife — Biophysics

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Dilated cardiomyopathy mutation E525K in human beta-cardiac myosin stabilizes the interacting heads motif and super-relaxed state of myosin
Rasicci, D. V., Tiwari, P., Desetty, R., Sadler, F. R., Sivaramakrishnan, S., Craig, R., Yengo, C. M.
10.1101/2022.02.18.480995 — Posted: 2022-02-19 — Discussion: 2022-08-19  eLife
In situ single particle classification reveals distinct 60S maturation intermediates in cells
Lucas, B. A., Zhang, K., Loerch, S., Grigorieff, N.
10.1101/2022.04.10.487797 — Posted: 2022-04-10 — Discussion: 2022-08-17  eLife
Network architecture determines vein fate during spontaneous reorganization, with a time delay
Marbach, S., Ziethen, N., Bastin, L., Baeuerle, F., Alim, K.
10.1101/2021.12.29.474405 — Posted: 2021-12-30 — Discussion: 2022-08-12  eLife
HSPB5 disease-associated mutations have long-range effects on structure and dynamics through networks of quasi-ordered interactions
Woods, C. N., Ulmer, L. D., Janowska, M. K., Stone, N. L., James, E. I., Guttman, M., Bush, M. F., Klevit, R. E.
10.1101/2022.05.30.493970 — Posted: 2022-05-30 — Discussion: 2022-08-11  eLife
Multivalency, autoinhibition, and protein disorder in the regulation of interactions of dynein intermediate chain with dynactin and the nuclear distribution protein
Jara, K. A., Loening, N. M., Reardon, P. N., Yu, Z., Woonnimani, P., Brooks, C., Vesely, C. H., Barbar, E. J.
10.1101/2022.06.05.494868 — Posted: 2022-06-05 — Discussion: 2022-08-11  eLife
Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
Sivilotti, L., Ivica, J., Zhu, H., Lape, R., Gouaux, E.
10.1101/2022.05.03.490487 — Posted: 2022-05-04 — Discussion: 2022-08-09  eLife
Recovering mixtures of fast diffusing states from short single particle trajectories
Heckert, A. B., Dahal, L., Tjian, R., Darzacq, X.
10.1101/2021.05.03.442482 — Posted: 2021-05-04 — Discussion: 2022-08-09  eLife
Structural model of microtubule dynamics inhibition by Kinesin-4 from the crystal structure of KLP-12 - tubulin complex
Taguchi, S., Nakano, J., Imasaki, T., Kita, T., Saijo-Hamano, Y., Sakai, N., Shigematsu, H., Okuma, H., Shimizu, T., Nitta, E., Kikkawa, S., Mizobuchi, S., Niwa, S., Nitta, R.
10.1101/2022.02.14.480441 — Posted: 2022-02-15 — Discussion: 2022-08-09  eLife
Automated systematic evaluation of cryo-EM specimens with SmartScope
Bouvette, J., Huang, Q., Riccio, A. A., Copeland, W. C., Bartesaghi, A., Borgnia, M. J.
10.1101/2022.05.05.490801 — Posted: 2022-05-06 — Discussion: 2022-08-02  eLife
Structure of the lysosomal membrane fusion machinery
Shvarev, D., Schoppe, J., Koenig, C., Perz, A., Fuellbrunn, N., Kiontke, S., Langemeyer, L., Januliene, D., Schnelle, K., Kuemmel, D., Froehlich, F., Moeller, A., Ungermann, C.
10.1101/2022.05.05.490745 — Posted: 2022-05-05 — Discussion: 2022-08-02  eLife

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