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32 Reviews — eLife — Synthetic Biology

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Resurrecting essential amino acid biosynthesis in a mammalian cell
Trolle, J., McBee, R. M., Kaufman, A., Pinglay, S., Berger, H., German, S., Liu, L., Shen, M. J., Guo, X., Martin, J. A., Pacold, M., Jones, D. R., Boeke, J. D., Wang, H. H.
10.1101/2021.08.03.454854 — Posted: 2021-08-03 — Discussion: 2022-08-02  eLife
De novo designed receptor transmembrane domains enhance CAR-T cell cytotoxicity and attenuate cytokine release
Elazar, A., Chandler, N. J., Davey, A. S., Weinstein, J. Y., Nguyen, J. V., Trenker, R., Jenkins, M. R., Call, M. J., Call, M. E., Fleishman, S. J.
10.1101/2020.07.26.221598 — Posted: 2020-07-26 — Discussion: 2022-04-26  eLife
Dynamic spreading of chromatin-mediated gene silencing and reactivation between neighboring genes in single cells
Lensch, S., Herschl, M. H., Ludwig, C. H., Sinha, J., Hinks, M. M., Mukund, A., Fujimori, T., Bintu, L.
10.1101/2021.11.04.467237 — Posted: 2021-11-04 — Discussion: 2022-03-14  eLife
Measuring the tolerance of the genetic code to altered codon size
DeBenedictis, E. A., Esvelt, K. M., Soll, D.
10.1101/2021.04.26.441066 — Posted: 2021-04-26 — Discussion: 2022-03-11  eLife
Development and Characterization of PAR-Trackers: New Tools for Detecting Poly(ADP-ribose)
Kraus, W. L., Challa, S., Ryu, K. W., Whitaker, A. L., Abshier, J. C., Camacho, C. V.
10.1101/2021.08.02.454729 — Posted: 2021-08-02 — Discussion: 2022-03-07  eLife
Heterogeneity of the GFP fitness landscape and data-driven protein design
Gonzalez Somermeyer, L., Fleiss, A., Mishin, A. S., Bozhanova, N. G., Igolkina, A. A., Meiler, J., Alaball Pujol, M.-E., Putintseva, E. V., Sarkisyan, K. S., Kondrashov, F.
10.1101/2021.12.08.471728 — Posted: 2021-12-09 — Discussion: 2022-02-20  eLife
Resolving phylogenetic and biochemical barriers to functional expression of heterologous iron-sulphur cluster enzymes
Shomar, H., Garcia, P. S., Fernandez-Fueyo, E., D'Angelo, F., Pelosse, M., Manuel, R. R., Büke, F., Liu, S., van den Broek, N., Duraffourg, N., de Ram, C., Pabst, M., Gribaldo, S., Py, B., Ollagnier de Choudens, S., Bokinsky, G., Barras, F.
10.1101/2021.02.02.429153 — Posted: 2021-02-02 — Discussion: 2022-01-24  eLife
Modular, robust and extendible multicellular circuit design in yeast
Carignano, A., Chen, D. H., Mallory, C., Wright, C., Seelig, G., Klavins, E.
10.1101/2021.10.13.464175 — Posted: 2021-10-14 — Discussion: 2022-01-24  eLife
Enhanced Cas12a multi-gene regulation using a CRISPR array separator
Magnusson, J. P., Qi, L. S., Wu, L., Rios, A. R.
10.1101/2021.01.27.428408 — Posted: 2021-01-27 — Discussion: 2021-08-17  eLife
Mapping the Functional Landscape of the Receptor Binding Domain of T7 Bacteriophage by Deep Mutational Scanning
Huss, P., Meger, A., Leander, M., Nishikawa, K., Raman, S.
10.1101/2020.07.28.225284 — Posted: 2020-07-29 — Discussion: 2021-02-12  eLife

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