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268 Reviews — eLife — Cancer Biology

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Cancer cells differentially modulate mitochondrial respiration to alter redox state and enable biomass synthesis in nutrient-limited environments
Chang, S. M., Bin Munim, M., Trojan, S. E., Shevzov-Zebrun, A., Abbott, K. L., Vander Heiden, M. G.
10.1101/2025.05.09.653205 — Posted: 2025-05-10 — Discussion: 2025-06-27  eLife
p53-induced RNA-binding protein ZMAT3 inhibits transcription of a hexokinase to suppress mitochondrial respiration
Kumar, R., Couly, S., Muys, B. R., Li, X. L., Grammatikakis, I., Singh, R., Guest, M., Wen, X., Tang, W., Ambs, S., Jenkins, L. M., Pehrsson, E. C., Chari, R., Su, T.-P., Lal, A.
10.1101/2025.05.12.653341 — Posted: 2025-05-13 — Discussion: 2025-06-26  eLife
Design of combination therapeutics from protein response to drugs in ovarian cancer cells
Franz, A., Shen, C., Coscia, F., Munroe, K., Charaoui, L., Korkut, A., Mann, M., Luna, A., Sander, C.
10.1101/2025.04.28.651139 — Posted: 2025-05-02 — Discussion: 2025-06-25  eLife
PA2gamma promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP
Wang, J., Shi, Y., Wang, Y., Shen, Y., Liu, H., Sun, S., Wang, Y., Zhou, X., Zhou, Y., Zeng, X., Li, J., Chen, Q.
10.1101/2024.07.23.604769 — Posted: 2024-07-23 — Discussion: 2025-06-10  eLife
PRMT1-Mediated Metabolic Reprogramming Promotes Leukemogenesis
Su, H., Sun, Y., Guo, H., Sun, C.-w., Chen, Q., Liu, S., Li, A., Gao, M., Zhao, R., Raffel, G., Jin, J., Qu, C.-K., Yu, M., Klug, C. A., Zheng, Y. G., Ballinger, S., Kutny, M., Long Zheng, X., Chong, Z., Senevirathne, C., Gross, S., Chen, Y., Luo, M., Zhao, X.
10.1101/2024.12.12.628174 — Posted: 2024-12-17 — Discussion: 2025-06-04  eLife
Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition
Arabanian, L. S., Adamsson, J., Unger, A., Di Lucrezia, R., Bergbrede, T., Ashouri, A., Larsson, E., Nussbaumer, P., Klebl, B. M., Palmqvist, L., Gustafsson, C. M.
10.1101/2022.09.23.509145 — Posted: 2022-09-25 — Discussion: 2025-05-30  eLife
NOLC1 Suppresses Immuno-chemotherapy by Inhibiting p53-mediated Ferroptosis in Gastric Cancer
Zhao, S., Lin, J., Zhu, B., Jin, Y., Dong, Q., Ruan, X., Jin, D., Yi, Y., Bai, B., Li, H., Liang, D., Lu, J., Meng, L., Wang, X., Cui, Y., Gu, Y., Shen, X., Lu, X., Rao, S., Sun, W.
10.1101/2024.11.05.622078 — Posted: 2024-11-07 — Discussion: 2025-05-29  eLife
Single-cell dissection of prognostic architecture and immunotherapy response in Helicobacter pylori infection associated gastric cancer
Zhang, X., Zhang, G., Sang, S., Fei, Y., Cao, X., Song, W., Liu, F., Che, J., Tao, H., Wang, H., Zhang, L., Guan, Y., Rong, S., Pei, L., Yao, S., Wang, Y., Zhang, M., Liu, C.
10.1101/2024.05.31.596846 — Posted: 2024-05-31 — Discussion: 2025-05-21  eLife
Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer
Zhang, C., Zhang, Z., Wu, Y., Cheng, J., Luo, K., Li, Z., Zhang, M., Wang, J., Li, Y.
10.1101/2024.05.21.595220 — Posted: 2024-05-23 — Discussion: 2025-05-21  eLife
Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML
Whittle, J., Meyer, S., Lacaud, G., Baker, S. M., Iqbal, M.
10.1101/2024.10.29.620871 — Posted: 2024-11-03 — Discussion: 2025-05-15  eLife

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