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82 Reviews — EMBO Press — Neuroscience

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Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
Polanco, J. C., Akimov, Y., Fernandes, A., Hand, G. R., Briner, A., van Roijen, M., Balistreri, G., Gotz, J.
10.1101/2022.04.26.489622 — Posted: 2022-04-28 — Discussion: 2023-05-14  EMBO Press
Morphofunctional changes at the active zone during synaptic vesicle exocytosis
Radecke, J., Seeger, R., Kadkova, A., Laugks, U., Khosrozadeh, A., Goldie, K. N., Lucic, V., Sorensen, J. B., Zuber, B.
10.1101/2022.03.07.483217 — Posted: 2022-03-07 — Discussion: 2023-04-12  EMBO Press
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
Peviani, M., Das, S., Patel, J., Jno-Charles, O., Kumar, R., Zguro, A., Mathews, T. D., Milazzo, R., Cavalca, E., Poletti, V., Biffi, A.
10.1101/2022.03.03.482460 — Posted: 2022-03-04 — Discussion: 2023-04-12  EMBO Press
iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation
Tristan Noguero, A., Fernandez-Carasa, I., Calatayud, C., Bermejo-Casadesus, C., Campa, L., Artigas, F., Domingo-Jimenez, R., Ibanez, S., Pineda, M., Artuch, R., Raya, A., Garcia Cazorla, A., Consiglio, A.
10.1101/2022.02.24.481741 — Posted: 2022-02-26 — Discussion: 2023-03-15  EMBO Press
An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
Avar, M., Heinzer, D., Thackray, A. M., Liu, Y., Hruska-Plochan, M., Sellitto, S., Schaper, E. W., Pease, D. P., Yin, J.-A., Lakkaraju, A. K., Emmenegger, M., Losa, M., Chincisan, A., Hornemann, S., Polymenidou, M., Bujdoso, R., Aguzzi, A.
10.1101/2022.03.03.482765 — Posted: 2022-03-04 — Discussion: 2023-03-15  EMBO Press
SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
Lee, A., Yi, N., Khaled, H., Feller, B., Chofflet, N., Takahashi, H.
10.1101/2022.07.26.501499 — Posted: 2022-07-28 — Discussion: 2023-02-15  EMBO Press
A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
Grochowska, K. M., Kaushik, R., Gomes, G. M., Raman, R., Baer, J., Bayraktar, G., Samer, S., Reyes-Resina, I., Spilker, C., Morawski, M., Rossner, S., Navarro Brugal, G., Karpova, A., Kreutz, M. R.
10.1101/2020.01.08.898304 — Posted: 2020-01-09 — Discussion: 2023-02-01  EMBO Press
Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
Frangos, Z. J., Wilson, K. A., Aitken, H. M., Cantwell Chater, R., Vandenberg, R. J., O'Mara, M. L.
10.1101/2022.08.31.506132 — Posted: 2022-09-03 — Discussion: 2023-01-28  EMBO Press
An isoform-specific function of Cdc42 in regulating mammalian Exo70 during axon formation
Ravindran, P., Puschel, A. W.
10.1101/2022.07.01.498448 — Posted: 2022-07-03 — Discussion: 2023-01-24  EMBO Press
NOTCH3 active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model
Oliveira, D. V., Coupland, K., Jin, S., Del Gaudio, F., Wang, S., Fox, R., Rutten, J. W., Sandin, J., Lundkvist, J., Lesnik Oberstein, S. A., Lendahl, U., Karlstrom, H.
10.1101/2022.07.11.499563 — Posted: 2022-07-12 — Discussion: 2023-01-19  EMBO Press

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