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84 Reviews — EMBO Press — Neuroscience

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Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain
Lemaitre, P., Tareen, S., Pasciuto, E., Mascali, L., Martirosyan, A., Callaerts-Vegh, Z., Dooley, J., Holt, M., Yshii, L., Liston, A.
10.1101/2022.03.01.482519 — Posted: 2022-03-04 — Discussion: 2023-05-25  EMBO Press
The piRNA pathway sustains adult neurogenesis by repressing protein synthesis
Gasperini, C., Pelizzoli, R., Lo Van, A., Mangoni, D., Cossu, R. M., Pascarella, G., Bianchini, P., Bielefeld, P., Scarpato, M., Pons-Espinal, M., Sanges, R., Diaspro, A., Fitzsimons, C. P., Carninci, P. P., Gustincich, S., De Pietri Tonelli, D.
10.1101/2020.09.15.297739 — Posted: 2020-09-15 — Discussion: 2023-05-17  EMBO Press
Genome-wide CRISPRi screening reveals regulators of Alzheimee's tau pathology shared between exosomal and vesicle-free tau seeds.
Polanco, J. C., Akimov, Y., Fernandes, A., Hand, G. R., Briner, A., van Roijen, M., Balistreri, G., Gotz, J.
10.1101/2022.04.26.489622 — Posted: 2022-04-28 — Discussion: 2023-05-14  EMBO Press
An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model
Peviani, M., Das, S., Patel, J., Jno-Charles, O., Kumar, R., Zguro, A., Mathews, T. D., Milazzo, R., Cavalca, E., Poletti, V., Biffi, A.
10.1101/2022.03.03.482460 — Posted: 2022-03-04 — Discussion: 2023-04-12  EMBO Press
Morphofunctional changes at the active zone during synaptic vesicle exocytosis
Radecke, J., Seeger, R., Kadkova, A., Laugks, U., Khosrozadeh, A., Goldie, K. N., Lucic, V., Sorensen, J. B., Zuber, B.
10.1101/2022.03.07.483217 — Posted: 2022-03-07 — Discussion: 2023-04-12  EMBO Press
iPSC-based modeling of THD recapitulates disease phenotypes and reveals neuronal malformation
Tristan Noguero, A., Fernandez-Carasa, I., Calatayud, C., Bermejo-Casadesus, C., Campa, L., Artigas, F., Domingo-Jimenez, R., Ibanez, S., Pineda, M., Artuch, R., Raya, A., Garcia Cazorla, A., Consiglio, A.
10.1101/2022.02.24.481741 — Posted: 2022-02-26 — Discussion: 2023-03-15  EMBO Press
An Arrayed Genome-Wide Perturbation Screen Identifies the Ribonucleoprotein hnRNP K As Rate-Limiting for Prion Propagation
Avar, M., Heinzer, D., Thackray, A. M., Liu, Y., Hruska-Plochan, M., Sellitto, S., Schaper, E. W., Pease, D. P., Yin, J.-A., Lakkaraju, A. K., Emmenegger, M., Losa, M., Chincisan, A., Hornemann, S., Polymenidou, M., Bujdoso, R., Aguzzi, A.
10.1101/2022.03.03.482765 — Posted: 2022-03-04 — Discussion: 2023-03-15  EMBO Press
SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology
Lee, A., Yi, N., Khaled, H., Feller, B., Chofflet, N., Takahashi, H.
10.1101/2022.07.26.501499 — Posted: 2022-07-28 — Discussion: 2023-02-15  EMBO Press
A molecular mechanism by which amyloid-β induces transcriptional inactivation of CREB in Alzheimer's Disease
Grochowska, K. M., Kaushik, R., Gomes, G. M., Raman, R., Baer, J., Bayraktar, G., Samer, S., Reyes-Resina, I., Spilker, C., Morawski, M., Rossner, S., Navarro Brugal, G., Karpova, A., Kreutz, M. R.
10.1101/2020.01.08.898304 — Posted: 2020-01-09 — Discussion: 2023-02-01  EMBO Press
Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2
Frangos, Z. J., Wilson, K. A., Aitken, H. M., Cantwell Chater, R., Vandenberg, R. J., O'Mara, M. L.
10.1101/2022.08.31.506132 — Posted: 2022-09-03 — Discussion: 2023-01-28  EMBO Press

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