bioRxiv/medRxiv TRiP Review Activity

328 Reviews — All Partners — Genetics

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Maternal SETDB1 enables development beyond cleavage stages by extinguishing the MERVL-driven 2-cell totipotency transcriptional program in the mouse embryo
Zeng, T.-B., Fu, Z., Majewski, M. F., Liao, J., Adams, M., Szabo, P. E.
10.1101/2025.10.07.680892 — Posted: 2025-10-09 — Discussion: 2026-01-27  eLife
Reproducibility of Scientific Claims in Drosophila Immunity: A Retrospective Analysis of 400 Publications
Westlake, H., David, F., Tian, Y., Krakovic, K., Dolgikh, A., Juravlev, L., Esmangart de Bournonville, T., Carboni, A., Melcarne, C., Shan, T., Wang, Y., Mu, Y., Kotwal, A., Pirko, N., Boquete, J. P., Schupfer, F., Rommelaere, S., Poidevin, M., Liu, Z., Kondo, S., Ratnaparkhi, G. S., Chakrabarti, S., Liu, G., Masson, F., Li, X., Hanson, M. A., Jiang, H., Di Cara, F., Kurant, E., Lemaitre, B.
10.1101/2025.07.07.663442 — Posted: 2025-07-09 — Discussion: 2026-01-19  eLife
Genetic and environmental determinants of multicellular-like phenotypes in fission yeast
Kover, B., Cohen, C. E., Ralser, M., Heineike, B. M., Bähler, J.
10.1101/2023.12.15.571870 — Posted: 2023-12-16 — Discussion: 2026-01-15  Review Commons
Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner
Senaldi, L., Hassan, N., Cullen, S., Balaji, U., Trigg, N., Gu, J., Finkelstein, H., Phillips, K., Conine, C., Smith-Raska, M.
10.1101/2024.02.27.582278 — Posted: 2024-03-01 — Discussion: 2026-01-09  eLife
The Impact of Stability Considerations on Genetic Fine-Mapping
Aw, A., Jin, L. C., Ioannidis, N., Song, Y. S.
10.1101/2023.04.11.536456 — Posted: 2023-04-13 — Discussion: 2026-01-08  eLife
A default silencing mechanism restrains stress-induced genes in C. elegans
Ilbay, O., Gama, A. R., Jarosz, D. F., Morimoto, R., Fire, A.
10.1101/2025.10.22.683740 — Posted: 2025-10-23 — Discussion: 2026-01-02  eLife
Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes
Li, L., Hunter, S., Leach, S., Zhuang, Y., Liu, H., Gao, J., Zhang, Q., Stasevich, T. J., Kimura, H., Dowell, R. D., Zhang, G.
10.1101/2025.10.08.681188 — Posted: 2025-10-11 — Discussion: 2025-12-31  eLife
Translational reading frame determines the pathogenicity of C-terminal frameshift deletions in MeCP2: an alternative therapeutic approach
Guy, J., Hein, E., Alexander-Howden, B., von Bock und Polach, T., Mathieson, T., Kleinstiver, B. P., Zoghbi, H. Y., Bird, A. P.
10.1101/2025.08.31.673354 — Posted: 2025-09-03 — Discussion: 2025-12-29  eLife
Integrating bulk and single cell RNA-seq refines transcriptomic profiles of specific C. elegans neurons.
Barrett, A., Varol, E., Weinreb, A., Taylor, S. R., McWhirter, R., Cros, C., Basavaraju, M., Poff, A., Tipps, J. A., Majeed, M., Vidal, B., Wang, C., Yemini, E., Bayer, E. A., Sun, H., Hobert, O., Miller, D. M., Hammarlund, M.
10.1101/2022.04.05.487209 — Posted: 2022-04-08 — Discussion: 2025-12-29  eLife
Microbiota/gut/neuron axis promotes Drosophila ageing via Acetobacter, Tachykinin, and TkR99D
Marcu, D., Sannino, D., Dornan, A., Ibrahim, R., Kapoor, A., Wood, M., Dobson, A. J.
10.1101/2025.07.31.667994 — Posted: 2025-08-02 — Discussion: 2025-12-10  eLife

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