bioRxiv/medRxiv TRiP Review Activity

413 Reviews — All Partners — Cancer Biology

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VPS9D1-AS1 overexpression amplifies intratumoral TGF-β signaling and promotes tumor cell escape from CD8+ T cell killing in colorectal cancer

Yang, L., Dong, X., Liu, Z., Huang, X., Tan, J., Wen, T., Qu, H., Wang, Z.

10.1101/2022.05.12.491618 — Posted: 2022-05-13 — Discussion: 2022-10-06 eLife

Defining function of wild-type and patient specific TP53 mutations in a zebrafish model of embryonal rhabdomyosarcoma

Chen, J., Baxi, K., Lipsitt, A. E., Hensch, N. R., Wang, L., Baudin, A., Robledo, D. G., Bandyopadhyay, A., Sugalski, A., Challa, A. K., Gilbert, A. R., Tomlinson, G. E., Houghton, P., Chen, E. Y., Libich, D. S., Ignatius, M. S.

10.1101/2021.04.21.440757 — Posted: 2021-04-22 — Discussion: 2022-10-04 eLife

Beta human papillomavirus 8E6 promotes alternative end-joining

Hu, C., Bugbee, T., Palinski, R., Akinyemi, I., McIntosh, M. T., MacCarthy, T., Bhaduri-McIntosh, S., Wallace, N.

10.1101/2022.07.29.501983 — Posted: 2022-07-30 — Discussion: 2022-09-27 eLife

SHARPIN serine 146 phosphorylation mediates ARP2/3 interaction, cancer cell invasion, and metastasis

Butt, U., Khan, M. H., Pouwels, J., Westermarck, J.

10.1101/2022.01.21.477220 — Posted: 2022-01-23 — Discussion: 2022-09-15 Review Commons

Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS

Ilter, M., Kasmer, R., Jalalypour, F., Atilgan, C., Topcu, O., Karakas, N., Sensoy, O.

10.1101/2022.04.24.489309 — Posted: 2022-04-24 — Discussion: 2022-09-15 eLife

Covalent Disruptor of YAP-TEAD Association Suppresses Defective Hippo Signaling

Fan, M., Lu, W., Che, J., Kwiatkowski, N. P., Gao, Y., Seo, H.-S., Ficarro, S. B., Gokhale, P. C., Liu, Y., Geffken, E. A., Lakhani, J., Song, K., Kuljanin, M., Ji, W., Jiang, J., He, Z., Tse, J., Boghossian, A. S., Rees, M. G., Ronan, M. M., Roth, J. A., Mancias, J. D., Marto, J. A., Dhe-Paganon, S., Zhang, T., Gray, N.

10.1101/2022.05.10.491316 — Posted: 2022-05-11 — Discussion: 2022-09-09 eLife

Cancer missense mutations in the BRC repeats of BRCA2 protein disrupt RAD51 binding and activity leading to chemotherapeutic sensitivity

Jimenez-Sainz, J., Mathew, J., Garbarino, J., Eder, J. P., Jensen, R. B.

10.1101/2021.09.24.461749 — Posted: 2021-09-25 — Discussion: 2022-09-09 eLife

Revised International Staging System (R-ISS) stage-dependent analysis uncovers oncogenes and potential immunotherapeutic targets in multiple myeloma

Gong, B., Yuan, X., Zhang, Q., Jiang, T., Li, H., Xiao, J., Li, C., Luo, L., Shuai, P., Wang, L., Liu, Y., Yu, M., Shi, Y., Zhang, W., Zhang, Y., Zhong, L.

10.1101/2021.12.06.471423 — Posted: 2021-12-07 — Discussion: 2022-09-07 eLife

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

Lu, Y., Cho, T., Mukherjee, S., Malik, A. A., Gonzlez-Foutel, N., Oh, R., Langille, E., Al-Zahrani, K., Lin, Z., Rotter, V., Ashton-Prolla, P., Chemes, L. B., Moffat, J., Gingras, A.-C., Oren, M., Durocher, D., Schramek, D.

10.1101/2022.03.13.483372 — Posted: 2022-03-14 — Discussion: 2022-09-07 Review Commons

CD81 partners with CD44 in promoting exosome biogenesis, tumor cluster formation, and lung metastasis in triple negative breast cancer

Ramos, E. K., Tsai, C.-F., Dashzeveg, N. K., Jia, Y., Cao, Y., Manu, M., Taftaf, R., Hoffmann, A. D., El-Shennawy, L., Gritsenko, M. A., Adorno-Cruz, V., Schuster, E. J., Scholten, D., Patel, D., Liu, X., Patel, P., Wray, B., Zhang, Y., Zhang, S., Moore, R. J., Schipma, M. J., Liu, T., Tokars, V. L., Cristofanilli, M., Shi, T., Shen, Y., Liu, H.

10.1101/2022.02.23.481674 — Posted: 2022-02-25 — Discussion: 2022-08-31 Review Commons