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279 Reviews — eLife — Cancer Biology

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Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
Knight, J. R., Vlahov, N., Gay, D. M., Ridgway, R. A., Faller, L., Proud, C., Mallucci, G. R., von der Haar, T., Smales, C. M., Willis, A. E., Sansom, O. J.
10.1101/2021.05.05.442715 — Posted: 2021-05-05 — Discussion: 2021-06-28  eLife
HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
Miyamoto, R., Kanai, A., Okuda, H., Takahashi, S., Matsui, H., Inaba, T., Yokoyama, A.
10.1101/2020.10.20.347765 — Posted: 2020-10-21 — Discussion: 2021-06-22  eLife
Exosome component 1 cleaves single-stranded DNA and sensitizes kidney renal clear cell carcinoma cells to poly(ADP-ribose) polymerase inhibitor
Yang, Q., Xiao, Q., Liu, Q., Wang, L., Wang, N., Wang, K., Song, C.
10.1101/2021.04.18.440347 — Posted: 2021-04-19 — Discussion: 2021-06-03  eLife
KSR1-and ERK-dependent Translational Regulation of the Epithelial-to-Mesenchymal Transition
Rao, C., Frodyma, D. E., Southekal, S., Svoboda, R. A., Black, A. R., Guda, C., Mizutani, T., Clever, H., Johnson, K. R., Fisher, K. W., Lewis, R. E.
10.1101/2021.01.18.427224 — Posted: 2021-01-21 — Discussion: 2021-04-22  eLife
Oxaliplatin Resistance in Colorectal Cancer Enhances TRAIL Sensitivity Via Death Receptor 4 Upregulation and Lipid Raft Localization
Greenlee, J. D., Lopez Cavestany, M., Ortiz-Otero, N., Liu, K., Subramanian, T., Cagir, B., King, M. R.
10.1101/2021.03.05.434100 — Posted: 2021-03-05 — Discussion: 2021-04-21  eLife
USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J., Pinto-Fernandez, A., Turnbull, A. P., Lan, L., Charlton, T. M., Scott, H. C., Damianou, A., Vere, G., Riising, E. M., Da Costa, C., Krajewski, W. W., Guerin, D., Kearns, J., Ioannidis, S., Katz, M., O'Connell, J. C., Moncaut, N., Rosewell, I., Nye, E., Jones, N., Heride, C., Gersch, M., Wu, M., Dinsmore, C. J., Hammonds, T. R., Kim, S., Komander, D., Urbe, S., Clague, M. J., Kessler, B. M., Behrens, A.
10.1101/2020.11.17.377705 — Posted: 2020-11-17 — Discussion: 2021-04-06  eLife
Signaling amplitude molds the Ras mutation tropism of urethane
Counter, C., Li, s.
10.1101/2021.02.09.430515 — Posted: 2021-02-10 — Discussion: 2021-03-29  eLife
A systematic CRISPR screen reveals an IL-20/IL20RA-mediated peritoneal immune crosstalk to prevent the ovarian cancer metastasis
Li, J., Qin, X., Shi, J., Wang, X., Li, T., Xu, M., Chen, X., Zhao, Y., Han, J., Piao, Y., Zhang, W., Qu, P., Wang, L., Xiang, R., Shi, Y.
10.1101/2021.01.03.425154 — Posted: 2021-01-04 — Discussion: 2021-03-18  eLife
An NKX2-1/ERK/WNT feedback loop modulates gastric identity and response to targeted therapy in lung adenocarcinoma
Zewdu, R., Mehrabad, E. M., Ingram, K., Jones, A., Camolotto, S. A., Mendoza, M. C., Spike, B. T., Snyder, E. L.
10.1101/2020.02.25.965004 — Posted: 2020-02-26 — Discussion: 2021-03-01  eLife
Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
Inoue, Y., Nikolic, A., Farnsworth, D., Liu, A., Ladanyi, M., Somwar, R., Gallo, M., Lockwood, W.
10.1101/2020.11.12.368522 — Posted: 2020-11-13 — Discussion: 2021-02-25  eLife

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