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421 Reviews — eLife — Biophysics

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Molecular mechanism underlying desensitization of the proton-activated chloride channel PAC
Osei-Owusu, J., Ruan, Z., Matasic, D. S., Lu, W., Qiu, Z.
10.1101/2022.08.30.505880 — Posted: 2022-08-30 — Discussion: 2022-12-06  eLife
A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0
Zivanov, J., Oton, J., Ke, Z., Qu, K., Morado, D., Castano-Diez, D., von Kügelgen, A., Bharat, T., Briggs, J., Scheres, S.
10.1101/2022.02.28.482229 — Posted: 2022-02-28 — Discussion: 2022-12-02  eLife
Working strokes produced by curling protofilaments at disassembling microtubule tips can be biochemically tuned and vary with species
Murray, L. E., Kim, H., Rice, L. M., Asbury, C. L.
10.1101/2022.09.13.507824 — Posted: 2022-09-14 — Discussion: 2022-11-22  eLife
Structure of a LRRC8 chimera with physiologically relevant properties reveals heptameric assembly and pore-blocking lipids
Takahashi, H., Yamada, T., Denton, J. S., Strange, K., Karakas, E.
10.1101/2022.07.28.501913 — Posted: 2022-07-28 — Discussion: 2022-11-08  eLife
Cellular compartmentalisation and receptor promiscuity as a strategy for accurate and robust inference of position during morphogenesis
Iyer, K. S., Prabhakara, C., Mayor, S., Rao, M.
10.1101/2022.03.30.486187 — Posted: 2022-03-30 — Discussion: 2022-11-01  eLife
Structural characterization of human RPA70N association with DNA damage response proteins
Wu, Y., Zang, N., Fu, W., Zhou, C.
10.1101/2022.07.14.500000 — Posted: 2022-07-15 — Discussion: 2022-10-25  eLife
High-throughput imaging and quantitative analysis uncovers the nature of plasmid positioning by ParABS
Köhler, R., Murray, S. M.
10.1101/2022.03.29.486196 — Posted: 2022-03-31 — Discussion: 2022-10-25  eLife
Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A
Hoel, C. M., Zhang, L., Brohawn, S. G.
10.1101/2022.06.20.496907 — Posted: 2022-06-20 — Discussion: 2022-10-23  eLife
Revealing druggable cryptic pockets in the Nsp-1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography
Borsatto, A., Galdadas, I., Gervasio, F. L., Estarellas, C., Haider, S., Kozielski, F., Damfo, S., Ma, S.
10.1101/2022.05.20.492819 — Posted: 2022-05-20 — Discussion: 2022-10-23  eLife
Sublytic gasdermin-D pores captured in atomistic molecular simulations
Schaefer, S. L., Hummer, G.
10.1101/2022.06.02.494496 — Posted: 2022-06-03 — Discussion: 2022-10-19  eLife

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