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285 Reviews — eLife — Cancer Biology

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Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
Thirmanne, H. N., Wu, F., Janssens, D. H., Swanger, J., Feldman, H., Amezquita, R., Gottardo, R., Paddison, P. J., Henikoff, S., Clurman, B. E.
10.1101/2021.10.19.464955 — Posted: 2021-10-21 — Discussion: 2022-02-13  eLife
Regulation of protein complex partners as a compensatory mechanism in aneuploid tumors
Senger, G., Santaguida, S., Schaefer, M. H.
10.1101/2021.12.05.471308 — Posted: 2021-12-09 — Discussion: 2022-02-08  eLife
Reprogramming and redifferentiation of mucosal-associated invariant T cells reveals tumor inhibitory activity
Wakao, H., Sugimoto, C., Murakami, Y., Fujita, H., Ishii, E.
10.1101/2021.06.21.449226 — Posted: 2021-06-21 — Discussion: 2022-02-08  eLife
Proton export drives the Warburg Effect
Russell, S., Xu, L., Kam, Y., Abrahams, D., Ordway, B., Lopez, A., Bui, M. M., Johnson, J., Epstein, T., Ruiz, E., Lloyd, M., Swietach, P., Verduzco, D., Wojtkowiak, J., Gillies, R.
10.1101/2021.09.20.461019 — Posted: 2021-09-21 — Discussion: 2022-02-02  eLife
JAMMIT Analysis Defines 2 Semi-Independent Immune Processes Common to 29 Solid Tumors
Zitello, E., Vo, M., Bowler, S., Chen, S., Wenska, T., Khadka, V., Hoffmann, P., Okimoto, G., Deng, Y.
10.1101/2021.08.31.458339 — Posted: 2021-09-01 — Discussion: 2022-01-09  eLife
The protective effect of aspirin in colorectal carcinogenesis: a multiscale computational study from mutant evolution to age incidence curves
Wang, Y., Boland, C. R., Goel, A., Wodarz, D., Komarova, N.
10.1101/2021.05.11.443671 — Posted: 2021-05-12 — Discussion: 2021-12-24  eLife
Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference
Lynch, A. R., Arp, N. L., Zhou, A. S., Weaver, B. A., Burkard, M. E.
10.1101/2021.04.26.441466 — Posted: 2021-04-27 — Discussion: 2021-12-01  eLife
Stereo-specific Lasofoxifene Derivatives Reveal the Interplay between Estrogen Receptor Alpha Stability and Antagonistic Activity in ESR1 Mutant Breast Cancer Cells
Hosfield, D. J., Weber, S., Li, N.-S., Suavage, M., Sullivan, E., Nduwke, E., Han, R., Cush, S., Laine, M., Mader, S. C., Greene, G. L., Fanning, S. W.
10.1101/2021.08.27.457901 — Posted: 2021-08-28 — Discussion: 2021-12-01  eLife
Type I PRMTs and PRMT5 Inversely Regulate Post-Transcriptional Intron Detention
Maron, M. I., Casill, A. D., Gupta, V., Sidoli, S., Query, C. C., Gamble, M. J., Shechter, D.
10.1101/2021.08.20.457069 — Posted: 2021-08-20 — Discussion: 2021-11-24  eLife
Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Urtatiz, O., Haage, A., Tanentzapf, G., Van Raamsdonk, C. D.
10.1101/2021.07.26.453858 — Posted: 2021-07-26 — Discussion: 2021-11-10  eLife

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