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268 Reviews — eLife — Cancer Biology

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Stereo-specific Lasofoxifene Derivatives Reveal the Interplay between Estrogen Receptor Alpha Stability and Antagonistic Activity in ESR1 Mutant Breast Cancer Cells
Hosfield, D. J., Weber, S., Li, N.-S., Suavage, M., Sullivan, E., Nduwke, E., Han, R., Cush, S., Laine, M., Mader, S. C., Greene, G. L., Fanning, S. W.
10.1101/2021.08.27.457901 — Posted: 2021-08-28 — Discussion: 2021-12-01  eLife
Type I PRMTs and PRMT5 Inversely Regulate Post-Transcriptional Intron Detention
Maron, M. I., Casill, A. D., Gupta, V., Sidoli, S., Query, C. C., Gamble, M. J., Shechter, D.
10.1101/2021.08.20.457069 — Posted: 2021-08-20 — Discussion: 2021-11-24  eLife
Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma
Urtatiz, O., Haage, A., Tanentzapf, G., Van Raamsdonk, C. D.
10.1101/2021.07.26.453858 — Posted: 2021-07-26 — Discussion: 2021-11-10  eLife
AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in Castrate-Resistant Prostate Cancer
Kim, S., Jamalruddin, M. A. B., Au, C. C., Mukhtar, E., Portella, L., Berger, A., Worroll, D., Rickman, D. S., Nanus, D. M., Giannakakou, P.
10.1101/2021.06.03.446940 — Posted: 2021-06-03 — Discussion: 2021-11-10  eLife
ZHX2 Promotes HIF1α Oncogenic Signaling in Triple-Negative Breast Cancer
Fang, W., Liao, C., Shi, R., Simon, J., Ptacek, T., Zurlo, G., Ye, Y., Han, L., Fan, C., Ortiz, C. L., Lin, H.-R., Manocha, U., Luo, W., Kim, W. Y., Yang, L.-W., Zhang, Q.
10.1101/2021.05.27.445959 — Posted: 2021-05-28 — Discussion: 2021-10-15  eLife
The Pancreatic Tumor Microenvironment Buffers Redox Imbalance Imposed by Disrupted Mitochondrial Metabolism
Kerk, S. A., Lin, L., Myers, A. L., Chen, B., Sajjakulnukit, P., Robinson, A., Thurston, G., Nelson, B. S., Kemp, S. B., Steele, N. G., Hoffman, M. T., Wen, H.-J., Long, D., Ackenhusen, S. E., Ramos, J., Gao, X., Zhang, L., Andren, A., Nwosu, Z. C., Galban, S., Halbrook, C. J., Lombard, D. B., Ying, H., Crawford, H. C., Pasca di Magliano, M., Shah, Y. M., Lyssiotis, C. A.
10.1101/2020.08.07.238766 — Posted: 2020-08-07 — Discussion: 2021-10-13  eLife
HBO1-MLL interaction promotes AF4/ENL/P-TEFb-mediated leukemogenesis
Takahashi, S., Kanai, A., Okuda, H., Miyamoto, R., Kawamura, T., Matsui, H., Inaba, T., Takaori-Kondo, A., Yokoyama, A.
10.1101/2021.01.08.425834 — Posted: 2021-01-08 — Discussion: 2021-08-13  eLife
Zebrafish embryo screen identifies anti-metastasis drugs
Nakayama, J., Tan, L., Goh, B. C., Wang, S., Makinoshima, H., Zhiyuan, G.
10.1101/2021.03.04.434001 — Posted: 2021-03-05 — Discussion: 2021-08-11  eLife
MicroRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi
McNeal, A. S., Belote, R. L., Zeng, H., Barker, K., Torres, R., Shain, A. H., Andtbacka, R. H., Holmen, S. L., Lum, D. H., McCalmont, T., VanBrocklin, M. W., Wei, M. L., Lang, U. E., Judson-Torres, R. L.
10.1101/2020.05.21.109397 — Posted: 2020-05-24 — Discussion: 2021-07-07  eLife
Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2K
Knight, J. R., Vlahov, N., Gay, D. M., Ridgway, R. A., Faller, L., Proud, C., Mallucci, G. R., von der Haar, T., Smales, C. M., Willis, A. E., Sansom, O. J.
10.1101/2021.05.05.442715 — Posted: 2021-05-05 — Discussion: 2021-06-28  eLife

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