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257 Reviews — eLife — Molecular Biology

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Multi-omic rejuvenation of human cells by maturation phase transient reprogramming
Gill, D., Parry, A., Santos, F., Hernando-Herraez, I., Stubbs, T. M., Milagre, I., Reik, W.
10.1101/2021.01.15.426786 — Posted: 2021-01-17 — Discussion: 2022-03-01  eLife
Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer's model
Clarke, M. F., Reinitz, F., Chen, E., Nicolis di Robilant, B., Chuluun, B., Antony, J., Jones, R. C., Gubbi, N., Kolluru, S. S., Qian, D., Piltti, K., Monje, M., Anderson, A., Heller, H. C., Quake, S. R.
10.1101/2020.12.21.383059 — Posted: 2020-12-22 — Discussion: 2022-02-20  eLife
SARS-CoV-2 Nsp14 mediates the effects of viral infection on the host cell transcriptome
Zaffagni, M., Harris, J. M., Patop, I. L., Pamudurti, N. R., Nguyen, S., Kadener, S.
10.1101/2021.07.02.450964 — Posted: 2021-07-04 — Discussion: 2022-02-18  eLife
Epigenetic reprogramming by TET enzymes impacts co-transcriptional R-loops
de Almeida, S. F., Sabino, J. C., de Almeida, M. R., Abreu, P. L., Ferreira, A. M., Domingues, M. M., Santos, N. C., Azzalin, C., Rita Grosso, A.
10.1101/2021.04.26.441414 — Posted: 2021-04-27 — Discussion: 2022-02-14  eLife
Binary outcomes of enhancer activity underlie stable random monoallelic expression
Kissiov, D. U., Ethell, A., Chen, S., Wolf, N. K., Zhang, C., Dang, S. M., Jo, Y., Madsen, K. N., Paranjpe, I. D., Lee, A. Y., Chim, B., Raulet, D.
10.1101/2021.08.27.457979 — Posted: 2021-08-28 — Discussion: 2022-01-12  eLife
Hepatic miR-20b promotes nonalcoholic fatty liver disease by suppressing PPARα
Lee, Y. H., Jang, H.-J., Kim, S., Choi, S. S., Khim, K. W., Eom, H.-J., Hyun, J., Shin, K. J., Chae, Y. C., Kim, H., Park, J., Park, N. H., Woo, C.-Y., Hong, C. H., Koh, E. H., Nam, D., Choi, J. h.
10.1101/2021.06.07.447348 — Posted: 2021-06-07 — Discussion: 2021-12-15  eLife
DNA-PK Promotes DNA End Resection at DNA Double Strand Breaks in G0 cells
Tyler, J. K., Fowler, F. C., Peart, C., Chen, B.-R., Sleckman, B., Zolnerowich, N., Nussenzweig, A., Pavani, R., Wu, W., Paiano, j.
10.1101/2021.10.21.465258 — Posted: 2021-10-21 — Discussion: 2021-12-02  eLife
A Helicase-tethered ORC Flip Enables Bidirectional Helicase Loading
Gupta, S., Friedman, L. J., Gelles, J., Bell, S. P.
10.1101/2021.10.06.463322 — Posted: 2021-10-06 — Discussion: 2021-12-01  eLife
Establishment of Developmental Gene Silencing by Ordered Polycomb Complex Recruitment in Early Zebrafish Embryos
Cairns, B. R., Hickey, G. J. M., Wike, C., Nie, X., Guo, Y., Murphy, P. J., Tan, M.
10.1101/2021.03.16.435592 — Posted: 2021-03-16 — Discussion: 2021-11-30  eLife
A DCL3 dicing code within Pol IV-RDR2 transcripts diversifies the siRNA pool guiding RNA-directed DNA methylation
Loffer, A., Singh, J., Fukudome, A., Mishra, V., Wang, F., Pikaard, C. S.
10.1101/2021.09.06.459145 — Posted: 2021-09-06 — Discussion: 2021-11-26  eLife

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