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153 Reviews — eLife — Physiology

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Natural xanthones as α-Mangostin induce vasorelaxation via binding to key gating residues in the S6 domain of BK channels
Cordeiro, S., Patejdl, R., Baukrowitz, T., Musinszki, M. A.
10.1101/2025.10.02.680041 — Posted: 2025-10-04 — Discussion: 2025-11-25  eLife
Postnatal hearing development limits early parent-to-offspring vocal communication and gates sensorimotor learning in the zebra finch
Anttonen, T., Christensen-Dalsgaard, J., Elemans, C. P.
10.1101/2024.05.03.592470 — Posted: 2024-05-06 — Discussion: 2025-11-14  eLife
NAD+ boosting by oral nicotinamide mononucleotide administration regulates key metabolic and immune pathways through SIRT1 dependent and independent mechanisms to mitigate diet-induced obesity and dyslipidemia in mice.
Majeed, Y., Halabi, N. M., Engelke, R., Sarwath, H., Al-Noubi, M. N., Choi, S., Madani, A. Y., Agha, M. V., Vakayil, M., Schmidt, F., Mazloum, N. A.
10.1101/2025.06.20.660826 — Posted: 2025-06-26 — Discussion: 2025-11-10  eLife
The titin N2A-MARP signalosome constrains muscle longitudinal hypertrophy in response to stretch
Van der Pijl, R., Gohlke, J., Strom, J., Peters, E., Shen, S., Conijn, S., Hourani, Z., Lange, S., Chen, J., Langlais, P., Labeit, S., Granzier, H. L., Ottenheijm, C.
10.1101/2025.06.19.660595 — Posted: 2025-06-25 — Discussion: 2025-11-04  eLife
Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila
Gera, J., Agard, M., Nave, H., Sajadi, F., Thorat, L., Kondo, S., Nassel, D., Paluzzi, J.-P. V., Zandawala, M.
10.1101/2024.02.07.579245 — Posted: 2024-02-10 — Discussion: 2025-10-15  eLife
Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline
Sebag, S. C., Neff, T., Qian, Q., Asghari, A., Wang, Z., Zhang, Z., Li, M., Hao, M., Lira, V., Sun, H., Potthoff, M. J., Yang, L.
10.1101/2025.07.01.662628 — Posted: 2025-07-04 — Discussion: 2025-10-03  eLife
Orco regulates the circadian activity of pheromone-sensitive olfactory receptor neurons in hawkmoths
Vijayan, A., Forlino, M., Chang, Y., Rojas, P., Schroeder, K., Schneider, A. C., Garcia, M. E., Stengl, M.
10.1101/2025.06.17.659282 — Posted: 2025-06-19 — Discussion: 2025-09-30  eLife
Modeling metabolic disease susceptibility and resilience in genetically diverse mice
Baker, C. N., Harder, J. M., Skelly, D. A., Gaca, M., Gerdes Gyuricza, I., Vincent, M., Ingalls, A., Keller, M. P., Attie, A. D., Braun, M., Stitzel, M. L., Liu, E. T., Rosenthal, N. T., Churchill, G. A.
10.1101/2025.02.12.637923 — Posted: 2025-02-16 — Discussion: 2025-09-11  eLife
The denitrosylase SCoR2 controls cardioprotective metabolic reprogramming
Grimmett, Z. W., Zhang, R., Zhou, H.-L., Chen, Q., Miller, D., Qian, Z., Lin, J., Kalra, R., Gross, S., Koch, W. J., Premont, R. T., Stamler, J. S.
10.1101/2025.03.12.642752 — Posted: 2025-03-14 — Discussion: 2025-09-01  eLife
Megakaryocytes build a cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Masson, C., Scandola, C., Rinckel, J.-Y., Proamer, F., Janus-Bell, E., Batool, F., OSMANI, N., GOETZ, J. G., Mallo, L., Leon, C., Bornert, A., Poincloux, R., destaing, o., Lehmann, M., Eckly, A.
10.1101/2024.09.30.615769 — Posted: 2024-10-01 — Discussion: 2025-09-01  eLife

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