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551 Reviews — eLife — Developmental Biology

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Arrayed single-gene perturbations identify drivers of human anterior neural tube closure
Huang, R. E., Anand, G. M., Megale, H. C., Chen, J., Abraham-Igwe, C., Ramanathan, S.
10.1101/2025.07.21.665862 — Posted: 2025-07-22 — Discussion: 2026-04-23  eLife
Drosophila ryanodine receptor gene triggers functional and developmental muscle properties and could be used to assess the impact of human RYR1 mutations
Jagla, K., Zmojdzian, M., Teresa, J., Cherik, F., Dubinska-Magiera, M., Migocka-Patrzalek, M., Daczewska, M., Rendu, J., Sarret, C.
10.1101/2025.11.06.686948 — Posted: 2025-11-08 — Discussion: 2026-04-22  eLife
A cell atlas of the human outflow tract of the heart and its adult derivatives
Leshem, R., Murtuza Baker, S., Mallen, J., Wang, L., Dark, J., Bamforth, S., Bobola, N.
10.1101/2023.04.05.535627 — Posted: 2023-04-06 — Discussion: 2026-04-20  eLife
In vitro sexual dimorphism establishment in schistosomes
Pichon, R., Lotkowska, M. E., Bulathsinghalage, J. L., McMath, M., Evans, M., Hulme, B. J., Ambridge, K., Sankaranarayanan, G., Kershenbaum, S., Davey, S. D., Forde-Thomas, J., Hoffmann, K. F., Berriman, M., Rinaldi, G.
10.64898/2026.01.20.700612 — Posted: 2026-01-23 — Discussion: 2026-04-20  eLife
Transcriptional control of compartmental boundary positioning during Drosophila wing development
Aguilar, G., Sickmann, M. E., Born, G., Bieli, D., Affolter, M., Müller, M.
10.1101/2023.08.05.552106 — Posted: 2023-08-06 — Discussion: 2026-04-16  eLife
Linage priming and cell type proportioning depends on the interplay between stochastic and deterministic factors
Salvidge, W., Brimson, C., Gruenheit, N., Huang, L.-Y., Pears, C., Wolf, J., Thompson, C.
10.1101/2025.01.08.631908 — Posted: 2025-01-08 — Discussion: 2026-04-16  eLife
Inverted Assembly of the Lens Within Ocular Organoids Reveals Alternate Paths to Ocular Morphogenesis
Stahl, E. F., Delgado-Toscano, M. A., Saravanan, I., Paneva, A., Wittbrodt, J., Zilova, L.
10.1101/2025.04.17.649366 — Posted: 2025-04-19 — Discussion: 2026-04-16  eLife
Cellular basis of accelerated whole-tooth regeneration
Mubeen, T., He, H., Gruenhagen, G., Satoskar, A., Streelman, J. T.
10.64898/2026.01.06.697137 — Posted: 2026-01-07 — Discussion: 2026-04-16  eLife
Genetically engineered ESC-derived embryos reveal Vinculin-dependent force responses required for mammalian neural tube closure
Prudhomme, I. S., Brooks, E. R., Taneja, N., Bhattacharya, B., LaFleche, B. J., Furuta, Y., Zallen, J. A.
10.64898/2025.12.22.696028 — Posted: 2025-12-25 — Discussion: 2026-04-08  eLife
Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish
Baltaci, O. F., Usseglio Gaudi, A., Dudczig, S., Wang, W., Rondon-Galeano, M. C., Lim, Y.-W., Rae, J., Lagendijk, A., Parton, R. G., Farley, A., Hogan, B. M.
10.1101/2024.11.18.624089 — Posted: 2024-11-19 — Discussion: 2026-04-08  eLife

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