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81 Reviews — EMBO Press — Cancer Biology

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Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy
Pekkarinen, M., Nordfors, K., Uusi-Makela, J., Kytola, V., Rauhala, M., Urhonen, H., Hayrynen, S., Afyounian, E., Yli-Harja, O., Zhang, W., Helen, P., Lohi, O., Haapasalo, H., Haapasalo, J., Nykter, M., Kesseli, J., Granberg, K. J.
10.1101/2022.03.14.483566 — Posted: 2022-03-16 — Discussion: 2024-04-27  EMBO Press
CRISPR-Cas9-mediated genome engineering exaggerates genomic deletion at 10q23.31 including the PTEN gene locus mimicking cancer profiles
Geng, K., Merino, L. G., Veiga, R. G., Sommerauer, C., Epperlein, J., Brinkman, E. K., Kutter, C.
10.1101/2023.04.05.535680 — Posted: 2023-04-06 — Discussion: 2024-02-03  EMBO Press
Proteomic-based stratification of intermediate-risk prostate cancer patients
Zhong, Q., Rui, S., Aref, A. T., Noor, Z., Anees, A., Zhu, Y., Lucas, N., Poulos, R. C., Lyu, M., Zhu, T., Wang, B., Chen, G.-B., Wang, Y., Ding, X., Rutishauser, D., Rupp, N. J., Rueschoff, J. H., Poyet, C., Hermanns, T., Fankhauser, C., Martinez, M. R., Shao, W., Buljan, M., Neumann, J. F., Beyer, A., Hains, P. G., Reddel, R. R., Robinson, P. J., Aebersold, R., Guo, T., Wild, P. J.
10.1101/2023.03.03.530910 — Posted: 2023-03-03 — Discussion: 2024-01-26  EMBO Press
TUMOR ENDOTHELIAL CELL AUTOPHAGY IS A KEY VASCULAR-IMMUNE CHECKPOINT IN MELANOMA
Verhoeven, J., Jacobs, K. A., Rizzollo, F., Lodi, F., Hua, Y., Pozniak, J., Srinvasan, A. N., Houbaert, D., Shankar, G., More, S., Schaaf, M. B., Dubroja Lakic, N., Ganne, M., Lamote, J., Van Weyenbergh, J., Boon, L., Bechter, O., Bosisio, F., Bertrand, M., Marine, J. C., Lambrechts, D., Bergers, G., Agrawal, M., Agostinis, P.
10.1101/2023.04.21.537799 — Posted: 2023-04-21 — Discussion: 2023-12-16  EMBO Press
Paralog dispensability shapes homozygous deletion patterns in tumor genomes
De Kegel, B., Ryan, C. J.
10.1101/2022.06.20.496722 — Posted: 2022-06-20 — Discussion: 2023-12-13  EMBO Press
Downregulation of stromal syntenin sustains AML development
Leblanc, R., Ghossoub, R., Goubard, A., Castellano, R., Fares, J., Camoin, L., Audebert, S., Balzano, M., Boutayeh, B., Fauriat, C., Vey, N., Borg, J.-P., Collette, Y., Aurrand-Lions, M., David, G., Zimmermann, P.
10.1101/2023.02.15.527799 — Posted: 2023-02-15 — Discussion: 2023-12-12  EMBO Press
NRF2 connects Src tyrosine kinase to ferroptosis resistance in glioblastoma
Barila, D., Cirotti, C., Taddei, I., Contadini, C., Pepe, G., De Bardi, M., Borsellino, G., Helmer-Citterich, M.
10.1101/2023.05.08.539792 — Posted: 2023-05-09 — Discussion: 2023-12-09  EMBO Press
YAP antagonizes TEAD-mediated AR signaling and prostate cancer growth
Zhuo, S., Li, X., Cho, Y. S., Liu, Y., Yang, Y., Zhu, J., Jiang, J.
10.1101/2022.08.01.502314 — Posted: 2022-08-03 — Discussion: 2023-12-01  EMBO Press
PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
Nikolatou, K., Sandilands, E., Roman-Fernandez, A., Cumming, E. M., Freckmann, E. C., Lilla, S., Buetow, L., McGarry, L., Neilson, M., Shaw, R., Strachan, D., Miller, C., Huang, D. T., McNeish, I. A., Norman, J. C., Zanivan, S., Bryant, D.
10.1101/2022.11.29.518198 — Posted: 2022-11-29 — Discussion: 2023-09-06  EMBO Press
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
Iyer, S. R., Nusser, K., Jones, K., Shinde, P., Beach, C. Z., Keddy, C., Aguero, E., Force, J., Shinde, U., Davare, M. A.
10.1101/2022.12.27.521482 — Posted: 2022-12-27 — Discussion: 2023-09-02  EMBO Press

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