bioRxiv/medRxiv TRiP Review Activity

45 Reviews — All Partners — Pharmacology and Toxicology

Most recent first Previous |  Page 2: Articles 11-20  | Next

Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice
Lavigna, G., Grasso, A., Pasini, C., Grande, V., Mignogna, L., Restelli, E., Masone, A., Fracasso, C., Lucchetti, J., Gobbi, M., Chiesa, R.
10.1101/2024.04.30.591862 — Posted: 2024-05-03 — Discussion: 2024-07-02  Review Commons
Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)
Zhang, T., Ambrodji, A., Huang, H., Bouchonville, K. J., Etheridge, A. S., Schmidt, R. E., Bembenek, B. M., Temesgen, Z. B., Wang, Z., Innocenti, F., Stroka, D., Diasio, R. B., Largiader, C. R., Offer, S.
10.1101/2023.11.01.565230 — Posted: 2023-11-05 — Discussion: 2024-04-15  eLife
Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia
Zhou, L., Ni, C., Liao, R., Tang, X., Yi, T., Ran, M., Huang, M., Liao, R., Zhou, X., Qin, D., Wang, L., Huang, F., Xie, X., Wan, Y., Luo, J., Wang, Y., Wu, J.
10.1101/2023.12.16.571981 — Posted: 2023-12-17 — Discussion: 2024-03-25  eLife
PSTPIP2 ameliorates aristolochic acid nephropathy by suppressing interleukin-19-mediated neutrophil extracellular trap formation
Du, C., Dong, J., Xu, C., Jia, P., Cai, N., Wang, Q., Zhang, Z., Jiang, L., Jiang, W., Feng, R., Li, J., Huang, C., Ma, T.
10.1101/2023.07.24.550330 — Posted: 2023-07-26 — Discussion: 2024-01-01  eLife
Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology
Heitmann, S., Vandenberg, J. I., Hill, A. P.
10.1101/2023.04.19.537441 — Posted: 2023-04-20 — Discussion: 2023-11-06  eLife
Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma
Liu, H., Liu, M., Tian, X., Wang, H., Gao, J., Li, H., Zhao, Z., Liu, Y., Liu, C., Chen, X., Yang, Y.
10.1101/2022.12.06.519362 — Posted: 2022-12-10 — Discussion: 2023-10-03  eLife
A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer
Tian, Q., Zhang, P., Wang, Y., Si, Y., Yin, D., Weber, C. R., Fishel, M., Pollok, K. E., Qiu, B., Xiao, F., Chong, A.
10.1101/2023.02.15.528599 — Posted: 2023-02-15 — Discussion: 2023-09-28  eLife
Death by a Thousand Cuts -- Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology
Outhwaite, I. R., Singh, S., Berger, B.-T., Knapp, S., Chodera, J. D., Seeliger, M. A.
10.1101/2023.01.13.523972 — Posted: 2023-01-16 — Discussion: 2023-09-27  eLife
Characterization of the bioaccumulation and toxicity of copper pyrithione, an antifouling compound, on juveniles of rainbow trout
Bourdon, C., Cachot, J., Gonzalez, P., Couture, P.
10.1101/2023.01.31.526498 — Posted: 2023-01-31 — Discussion: 2023-09-25  Peer Community In
A generic binding pocket for small molecule IKs activators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes
Chan, M., Sahakyan, H., Eldstrom, J., Sastre, D., Wang, Y., Dou, Y., Pourrier, M., Vardanian, V., Fedida, D.
10.1101/2023.02.27.530167 — Posted: 2023-02-27 — Discussion: 2023-07-31  eLife

Evaluation Sources