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281 Reviews — eLife — Molecular Biology

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Introducing the CRISPR/Cas9 cytosine base editor toolbox "LeishBASEedit" - Gene editing and high-throughput screening in Leishmania without requiring DNA double-strand breaks, homologous recombination or donor DNA
Beneke, T., Engstler, M.
10.1101/2022.12.08.519658 — Posted: 2022-12-08 — Discussion: 2023-03-16  eLife
A TBP-independent mechanism for RNA Polymerase II transcription
Kwan, J. Z. J., Nguyen, T. F., Budzynski, M. A., Cui, J., Price, R. M., Teves, S. S.
10.1101/2021.03.28.437425 — Posted: 2021-03-29 — Discussion: 2023-03-16  eLife
Integrating analog and digital modes of gene expression at Arabidopsis FLC
Antoniou-Kourounioti, R. L., Meschichi, A., Reeck, S., Berry, S., Menon, G., Zhao, Y., Fozard, J., Holmes, T., Wang, H., Hartley, M., Dean, C., Rosa, S., Howard, M.
10.1101/2022.07.04.498694 — Posted: 2022-07-05 — Discussion: 2023-03-03  eLife
The long noncoding RNA Charme supervises cardiomyocytes maturation by controlling cell differentiation programs in the developing heart
Taliani, V., Buonaiuto, G., Desideri, F., Setti, A., Santini, T., Galfre, S., Nicoletti, C., Schirone, L., Mariani, D., Valente, V., Sciarretta, S., Perlas, E., Musaro, A., Bozzoni, I., Ballarino, M.
10.1101/2022.07.05.498800 — Posted: 2022-07-05 — Discussion: 2023-02-08  eLife
Nuclear m6A Reader YTHDC1 Promotes Muscle Stem Cell Activation/Proliferation by Regulating mRNA Splicing and Nuclear Export
Qiao, Y., Sun, Q., Chen, X., Wang, D., Su, R., Xue, Y., Sun, H., Wang, H.
10.1101/2022.08.07.503064 — Posted: 2022-08-07 — Discussion: 2023-02-08  eLife
Iron Status Influences Mitochondrial Disease Progression in Complex I-Deficient Mice
Grillo, A. S., Kelly, C., Ha, V. T., Bodart, C. M., Huff, S., Couch, R. K., Herrel, N. T., Kim, H. D., Zimmermann, A. O., Shattuck, J., Pan, Y.-C., Kaeberlein, M.
10.1101/2021.09.29.462431 — Posted: 2021-09-29 — Discussion: 2023-01-04  eLife
A Comprehensive Survey of C. elegans Argonaute Proteins Reveals Organism-wide Gene Regulatory Networks and Functions
Seroussi, U., Lugowski, A., Wadi, L., Lao, R. X., Willis, A. R., Zhao, W., Sundby, A. E., Charlesworth, A. G., Reinke, A. W., Claycomb, J. M.
10.1101/2022.08.08.502013 — Posted: 2022-08-08 — Discussion: 2023-01-03  eLife
Constitutive Activation and Oncogenicity Are Mediated by Loss of Helical Structure at the Cytosolic Boundary of the Thrombopoietin Receptor
Defour, J.-P., Leroy, E., Dass, S., Balligand, T., Levy, G., Mouton, C., Genet, L., Pecquet, C., Smith, S. O., Constantinescu, S.
10.1101/2022.06.30.498238 — Posted: 2022-06-30 — Discussion: 2023-01-02  eLife
STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis
Zhang, C., Zhao, S., Deng, H., Zhang, S., Wang, J., Song, X., Yu, D., Zhang, Y., Deng, W.
10.1101/2022.09.09.507335 — Posted: 2022-09-10 — Discussion: 2022-12-16  eLife
RNA localization mechanisms transcend cell morphology
Goering, R., Arora, A., Taliaferro, M.
10.1101/2022.04.14.488401 — Posted: 2022-04-14 — Discussion: 2022-12-16  eLife

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