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215 Reviews — eLife — Genetics

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An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR mediated homologous recombination
Kanca, O., Zirin, J., Hu, Y., Tepe, B., Dutta, D., Lin, W.-W., Ma, L., Ge, M., Zuo, Z., Liu, L.-P., Levis, R. W., Perrimon, N., Bellen, H. J.
10.1101/2021.12.24.474112 — Posted: 2021-12-24 — Discussion: 2022-06-23  eLife
Sperm mosaicism predicts transmission of de novo mutations to human blastocysts
Yang, X., Stanley, V., McEvoy-Venneri, J., Xu, X., Morales, A. J., Gleeson, J. G., Breuss, M. W.
10.1101/2022.03.28.486034 — Posted: 2022-03-28 — Discussion: 2022-06-08  eLife
Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons
Macdonald, L. A., Taylor, G. C. A., Brisbane, J. M., Christodoulou, E., Scott, L., Von Kriegsheim, A., Rossant, J. J., Gu, B., Wood, A. J.
10.1101/2022.01.13.476100 — Posted: 2022-01-13 — Discussion: 2022-05-27  eLife
Quantifying concordant genetic effects of de novo mutations on multiple disorders
Guo, H., Hou, L., Shi, Y., Jin, S. C., Zeng, X., Li, B., Lifton, R., Brueckner, M., Zhao, H.-y., Lu, Q.
10.1101/2021.06.13.448234 — Posted: 2021-06-14 — Discussion: 2022-05-10  eLife
Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory
Sump, B., Brickner, D. G., D'Urso, A., Kim, S. H., Brickner, J. H.
10.1101/2022.02.11.480054 — Posted: 2022-02-11 — Discussion: 2022-05-10  eLife
Zebrafish Cre/lox regulated UFlip alleles generated by CRISPR/Cas targeted integration provide cell-type specific conditional gene inactivation
Almeida, M. P., Kambakam, S., Liu, F., Ming, Z., Welker, J. M., Wierson, W. A., Schultz-Rogers, L. E., Ekker, S. C., Clark, K. J., Essner, J. J., McGrail, M.
10.1101/2021.06.18.448732 — Posted: 2021-06-18 — Discussion: 2022-05-09  eLife
H3K9me1/2 methylation limits the lifespan of C. elegans
Guang, S., Huang, M., Hong, M., Zhu, C., Chen, D., Chen, X., Feng, X.
10.1101/2021.10.27.466082 — Posted: 2021-10-28 — Discussion: 2022-04-22  eLife
S. pombe Rtf2 is Important for Replication Fork Barrier Activity of RTS1 via Splicing of Rtf1
Budden, A., Eravci, M., Campillo-Funollet, E., Naiman, K., Carr, A.
10.1101/2022.03.10.483798 — Posted: 2022-03-10 — Discussion: 2022-04-13  eLife
High-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice provides novel insight on the impact of host genetics
Doms, S., Fokt, H., Ruehlemann, M. C., Chung, C. J., Kuenstner, A., Ibrahim, S., Franke, A., Turner, L. M., Baines, J. F.
10.1101/2021.09.28.462095 — Posted: 2021-09-28 — Discussion: 2022-04-11  eLife
Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs
Cuevas-Navarro, A., Rodriguez-Munoz, L., Grego-Bessa, J., Cheng, A., Rauen, K. A., Urisman, A., McCormick, F., Jimenez, G., Castel, P.
10.1101/2022.01.04.474894 — Posted: 2022-01-05 — Discussion: 2022-04-08  eLife

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