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438 Reviews — All Partners — Cancer Biology

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Integrative DNA methylation analysis of pediatric brain tumors reveals tumor type-specific developmental trajectories and epigenetic signatures of malignancy
Pekkarinen, M., Nordfors, K., Uusi-Makela, J., Kytola, V., Rauhala, M., Urhonen, H., Hayrynen, S., Afyounian, E., Yli-Harja, O., Zhang, W., Helen, P., Lohi, O., Haapasalo, H., Haapasalo, J., Nykter, M., Kesseli, J., Granberg, K. J.
10.1101/2022.03.14.483566 — Posted: 2022-03-16 — Discussion: 2024-04-27  EMBO Press
mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated non-degradative ubiquitination of eIF4A1
Sun, H., Jiao, D., Zhao, X., Chen, Y., Shi, Q., Lv, Z., Li, Y., Gao, K., Wang, C.
10.1101/2023.09.27.559872 — Posted: 2023-09-29 — Discussion: 2024-04-26  eLife
Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration
Llanses Martinez, M., Nan, K., Bao, Z., Bacchetti, R., Yuan, S., Tyler, J., Le Guezennec, X., Bard, F. A., Rainero, E.
10.1101/2024.01.11.575153 — Posted: 2024-01-14 — Discussion: 2024-04-25  Review Commons
Ribosome subunit attrition and activation of the p53-MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition
Howard, G. C., Wang, J., Rose, K. L., Patel, P., Tsui, T., Florian, A. C., Lorey, S. L., Grieb, B. C., Smith, B. N., Slota, M. J., Reynolds, E. M., Goswami, S., Savona, M. R., Lee, T., Fesik, S. W., Liu, Q., Tansey, W. P.
10.1101/2023.07.26.550648 — Posted: 2023-07-29 — Discussion: 2024-04-09  eLife
Multi-omic dataset of patient-derived tumor organoids of neuroendocrine neoplasms
Alcala, N., Voegele, C., Mangiante, L., Sexton-Oates, A., Clevers, H., Fernandez-Cuesta, L., Dayton, T. L., Foll, M.
10.1101/2023.08.31.555732 — Posted: 2023-09-03 — Discussion: 2024-04-08  GigaScience
DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers
Pineda, J. M. B., Bradley, R. K.
10.1101/2023.07.10.548412 — Posted: 2023-07-11 — Discussion: 2024-04-08  eLife
mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming
Bischof, H., Maier, S., Koprowski, P., Kulawiak, B., Burgstaller, S., Jasinska, J., Serafimov, K., Gross, D., Schroth, W., Matt, L., Juarez Lopez, D. A., Bonzheim, I., Büttner, F. A., Fend, F., Schwab, M., Birkenfeld, A. L., Malli, R., Lämmerhofer, M., Bednarczyk, P., Szewczyk, A., Lukowski, R.
10.1101/2023.10.02.560571 — Posted: 2023-10-04 — Discussion: 2024-04-05  eLife
Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response
Warfvinge, R., Geironson Ulfsson, L., Dhapola, P., Safi, F., Sommarin, M. N. E., Soneji, S., Hjorth-Hansen, H., Mustjoki, S., Richter, J., Krishna Thakur, R., Karlsson, G.
10.1101/2023.08.16.553504 — Posted: 2023-08-18 — Discussion: 2024-04-04  eLife
DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
Mullen, N. J., Shukla, S. K., Thakur, R., Kollala, S. S., Wang, D., Chaika, N., LaBreck, D. A., Mallareddy, J. R., Price, D., Natarajan, A., Mehla, K., Sykes, D. B., Hollingsworth, M. A., Singh, P. K.
10.1101/2023.04.03.535399 — Posted: 2023-04-05 — Discussion: 2024-04-04  eLife
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells
Zhang, L., Hsu, J. I., Braekeleer, E. D., Chen, C.-w., Patel, T. D., Urya, H., Guzman, A. G., Martell, A. G., Waldvogel, S. M., Tovy, A., Callen, E., Murdaugh, R. L., Richard, R. U., Jansen, S., Vissers, L., de Vries, B. B., Nussenzweig, A., Huang, S., Coarfa, C., Anastas, J. N., Takahashi, K., Vassiliou, G. S., Goodell, M. A.
10.1101/2023.08.31.555634 — Posted: 2023-09-01 — Discussion: 2024-04-02  eLife

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