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204 Reviews — eLife — Genetics

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Ecdysone acts through cortex glia to regulate sleep in Drosophila
Li, Y., Haynes, P., Zhang, S. L., Yue, Z., Sehgal, A.
10.1101/2022.08.24.505204 — Posted: 2022-08-26 — Discussion: 2023-01-19  eLife
Regulatory dissection of the severe COVID-19 risk locus introgressed by Neanderthals
Jagoda, E., Marnetto, D., Montinaro, F., Richard, D., Pagani, L., Capellini, T. D.
10.1101/2021.06.12.448149 — Posted: 2021-06-14 — Discussion: 2023-01-02  eLife
MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size
Lafferty, M. J., Aygün, N., Krupa, O., Liang, D., Wolter, J. M., Geschwind, D. H., de la Torre-Ubieta, L., Stein, J. L.
10.1101/2022.03.31.486585 — Posted: 2022-04-01 — Discussion: 2022-12-30  eLife
Use of a ubiquitous gene-editing tool in budding yeast causes off-target repression of neighboring gene protein synthesis
Powers, E. N., Llacsahuanga Allcca, L., Doron-Mandel, E., Kim Kim, J., Jovanovic, M., Brar, G. A.
10.1101/2022.06.27.497784 — Posted: 2022-06-29 — Discussion: 2022-12-07  eLife
Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification
Feng, Z., Duren, Z., Xin, J., Yuan, Q., He, Y., Su, B., Wong, W. H., Wang, Y.
10.1101/2022.09.06.506769 — Posted: 2022-09-07 — Discussion: 2022-11-25  eLife
Interdependent progression of bidirectional sister replisomes in E. coli
Chen, P. J., McMullin, A. B., Visser, B. J., Mei, Q., Rosenberg, S. M., Bates, D. B.
10.1101/2022.07.27.501747 — Posted: 2022-07-27 — Discussion: 2022-11-25  eLife
Magnesium and the magnesium transporter UEX regulate sleep via Ca2+-dependent CREB signaling and a CNK-ERK pathway
Yuan, X., Zheng, H., Xu, X., Deng, H., Yang, X., Xi, Y.
10.1101/2022.09.26.509486 — Posted: 2022-09-27 — Discussion: 2022-11-25  eLife
Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations
Auwerx, C. M. P., Sadler, M. C., Reymond, A., Kutalik, Z., Porcu, E.
10.1101/2022.06.08.495285 — Posted: 2022-06-10 — Discussion: 2022-11-17  eLife
Gallbladder adenocarcinomas undergo subclonal diversification and selection from precancerous lesions to metastatic tumors
Kang, M., Na, H. Y., Kim, J.-W., Ahn, S., Lee, S., Ahn, S., Lee, J. H., Youk, J., Kim, H. T., Kim, K.-J., Suh, K. J., Lee, J. S., Kim, S. H., Kim, J. W., Kim, Y. J., Lee, K.-W., Yoon, Y.-S., Kim, J. H., Chung, J.-H., Han, H.-S., Lee, J. S.
10.1101/2022.03.31.486530 — Posted: 2022-04-01 — Discussion: 2022-11-15  eLife
Relating pathogenic loss-of function mutations in humans to their evolutionary fitness costs
Agarwal, I., Fuller, Z. L., Myers, S., Przeworski, M.
10.1101/2022.08.11.503594 — Posted: 2022-08-12 — Discussion: 2022-11-11  eLife

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