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31 Reviews — eLife — Synthetic Biology

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Synthetic gene circuits that selectively target RAS-driven cancers
Senn, G. V., Nissen, L., Benenson, Y.
10.1101/2024.11.11.622942 — Posted: 2024-11-11 — Discussion: 2025-09-25  eLife
Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
Pinon, L., Chabaud, M., Nivoit, P., Wong-Ng, J., Nguyen, T.-T., Paul, V., Goussard, S., Frachon, E., Obino, D., Gobaa, S., Dumenil, G.
10.1101/2024.02.09.579276 — Posted: 2024-02-10 — Discussion: 2025-08-29  eLife
High resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery
Howard, C. J., Abell, N. S., Osuna, B. A., Jones, E. M., Chan, L. Y., Chan, H., Artis, D. R., Asfaha, J. B., Bloom, J. S., Cooper, A. R., Liao, A., Mahdavi, E., Mohammed, N., Su, A. L., Uribe, G. A., Kosuri, S., Dickel, D. E., Lubock, N. B.
10.1101/2024.10.11.617882 — Posted: 2024-10-12 — Discussion: 2025-02-17  eLife
Effects of growth feedback on gene circuits: A dynamical understanding
Kong, L.-W., Shi, W., Tian, X., Lai, Y.-C.
10.1101/2023.06.06.543915 — Posted: 2023-06-07 — Discussion: 2025-01-23  eLife
A molecular proximity sensor based on an engineered, dual-component guide RNA
Choi, J., Chen, W., Liao, H., Li, X., Shendure, J.
10.1101/2023.08.14.553235 — Posted: 2023-08-14 — Discussion: 2024-11-11  eLife
De novo-designed minibinders expand the synthetic biology sensing repertoire
Weinberg, Z. Y., Soliman, S. S., Kim, M. S., Chen, I. P., Ott, M., El-Samad, H.
10.1101/2024.01.12.575267 — Posted: 2024-01-15 — Discussion: 2024-10-29  eLife
A synthetic method to assay polycystin ion channel biophysics
Larmore, M., Esarte Palomero, O., Kamat, N., DeCaen, P. G.
10.1101/2024.05.06.592666 — Posted: 2024-05-06 — Discussion: 2024-10-09  eLife
Light-driven synchronization of optogenetic clocks
Cannarsa, M. C., Liguori, F., Pellicciotta, N., Frangipane, G., Di Leonardo, R.
10.1101/2023.10.24.563722 — Posted: 2023-10-24 — Discussion: 2024-08-29  eLife
Intracellular Expression of a Fluorogenic DNA Aptamer Using Retron Eco2
Vibhute, M. A., Machatzke, C., Bigler, K., Krumpel, S., Summerer, D., Mutschler, H.
10.1101/2024.05.21.595248 — Posted: 2024-05-23 — Discussion: 2024-07-09  eLife
Targeted protein degradation systems to enhance Wnt signaling
Sampathkumar, P., Jung, H., Chen, H., Zhang, Z., Suen, N., Yang, Y., Huang, Z., Lopez, T., Benisch, R., Lee, S.-J., Ye, J., Yeh, W.-C., Li, Y.
10.1101/2023.12.08.570758 — Posted: 2023-12-08 — Discussion: 2024-05-23  eLife

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