Channel:  Aligning Science Across Parkinson's (ASAP)

403 Articles

Network analysis of α-synuclein pathology progression reveals p21-activated kinases as regulators of vulnerability
Vatsa, N., Brynildsen, J. K., Goralski, T. M., Kurgat, K., Meyerdirk, L., Breton, L., DeWeerd, D., Brasseur, L., Turner, L., Becker, K., Gallik, K. L., Bassett, D. S., Henderson, M. X.
10.1101/2024.10.22.619411 — Posted: 2024-10-22
Global cellular proteo-lipidomic profiling of diverse lysosomal storage disease mutants using nMOST
Kraus, F., He, Y., Swarup, S., Overmyer, K. A., Brenner, J., Capitanio, C., Bieber, A., Jen, A., Nightingale, N. M., Anderson, B. J., Lee, C., Paulo, J. A., Smith, I. R., Plitzko, J. M., Gygi, S. P., Schulman, B. A., Wilfling, F., Coon, J. J., Harper, J. W.
10.1101/2024.03.26.586828 — Posted: 2024-10-20
Cell-Type Resolved Protein Atlas of Brain Lysosomes Identifies SLC45A1-Associated Disease as a Lysosomal Disorder
Ghoochani, A., Heiby, J. C., Rawat, E. S., Medoh, U. N., Di Fraia, D., Dong, W., Gastou, M., Nyame, K., Laqtom, N. N., Gomez-Ospina, N., Ori, A., Abu-Remaileh, M.
10.1101/2024.10.14.618295 — Posted: 2024-10-15
Assembloid model to study loop circuits of the human nervous system
Miura, Y., Kim, J.-i., Jurjut, O., Kelley, K. W., Yang, X., Chen, X., Thete, M. V., Revah, O., Cui, B., Pachitariu, M., Pasca, S. P.
10.1101/2024.10.13.617729 — Posted: 2024-10-14
Amyloid-beta, alpha-synuclein and tau aggregated co-pathologies enhance neuropathology and neuroinflammation
Webster, J. M., Stone, W. J., Yang, Y.-T., Miller, A. T., Childers, G. M., Corbin-Stein, N. J., Mudium, N., Molina, J., Won, W.-J., Sandoval, I. M., Tyrrell, D. J., Manfredsson, F. P., Kordower, J. H., Harms, A. S.
10.1101/2024.10.13.618101 — Posted: 2024-10-13
GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes
Sivadasan Bindu, D., Savage, J. T., Brose, N., Bradley, L., Dimond, K., Tan, C. X., Eroglu, C.
10.1101/2023.01.17.524433 — Posted: 2024-10-11
Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex
Chen, M., Nguyen, T. N., Ren, X., Khuu, G., Cook, A. S. I., Zhao, Y., Yildiz, A., Lazarou, M., Hurley, J. H.
10.1101/2023.06.01.543278 — Posted: 2024-10-03
Endo-IP and Lyso-IP Toolkit for Endolysosomal Profiling of Human Induced Neurons
Hundley, F. V., Gonzalez-Lozano, M., Gottschalk, L. M., Cook, A. N. K., Zhang, J., Paulo, J. A., Harper, J. W.
10.1101/2024.09.24.614704 — Posted: 2024-09-26
Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics
Rizor, E. J., Dundon, N. M., Wang, J., Stasiak, J., Li, T., Bostan, A., Lapate, R. C., Grafton, S. T.
10.1101/2024.08.28.610129 — Posted: 2024-09-23
Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
Mendelsohn, A., Nikoobakht, L., Bikoff, J., Costa, R.
10.1101/2024.08.28.610136 — Posted: 2024-09-18

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