Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics
Rizor, E. J., Dundon, N. M., Wang, J., Stasiak, J., Li, T., Bostan, A., Lapate, R. C., Grafton, S. T.
10.1101/2024.08.28.610129 — Posted: 2024-09-23
Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses
Mendelsohn, A., Nikoobakht, L., Bikoff, J., Costa, R.
10.1101/2024.08.28.610136 — Posted: 2024-09-18
A STING-CASM-GABARAP Pathway Activates LRRK2 at Lysosomes
Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2023.10.31.564602 — Posted: 2024-09-11
Parkinson's Families Project: a UK-wide study of early onset and familial Parkinson's disease
Towns, C., Fang, Z.-H., Tan, M. M. X., Jasaityte, S., Schmaderer, T. M., Stafford, E. J., Pollard, M., Tilney, R., Hodgson, M., Wu, L., Labrum, R., Hehir, J., Polke, J., Lange, L. M., Schapira, A. H. V., Bhatia, K. P., Parkinsons Families Project (PFP) Study Group, , Global Parkinsons Genetics Program (GP2), , Singleton, A., Blauwendraat, C., Klein, C., Houlden, H., Wood, N. W., Jarman, P. R., Morris, H. R., Real, R.
10.1101/2023.12.05.23299397 — Posted: 2024-09-10
Neuronal alpha-Synuclein Disease Integrated Staging System performance in PPMI, PASADENA, and SPARK baseline cohorts.
Dam, T., Pagano, G., Brumm, M. C., Gochanour, C., Poston, K. L., Weintraub, D., Chahine, L. M., Coffey, C. S., Tanner, C. M., Kopil, C. M., Xiao, Y., Chowdhury, S., Concha-Marambio, L., DiBiaso, P., Foroud, T., Frasier, M., Jennings, D., Kieburtz, K., Merchant, K., Mollenhauer, B., Montine, T. J., Nudelman, K., Seibyl, J., Sherer, T., Singleton, A., Stephenson, D., Stern, M., Soto, C., Tolosa, E., Siderowf, A., Dunn, B., Simuni, T., Marek, K., and the Parkinson's Progression Markers Initiative
10.1101/2024.02.14.24302818 — Posted: 2024-09-10
Presynapses are mitophagy pit stops that prevent axon degeneration
Lam, W. K., Lindblom, R. S. J., Milky, B., Mazzachi, P., Hadian-Jazi, M., Kung, C., Khuu, G., Uoselis, L., Nguyen, T. N., Skulsuppaisarn, M., Saunders, T. L., Schmidt, M. F., Dewson, G., Fogel, A. I., Bardy, C., Lazarou, M.
10.1101/2024.09.09.611943 — Posted: 2024-09-09
The mitochondrial unfolded protein response promotes senescence in human microglia by increasing S-adenosylmethionine availability for polyamine synthesis.
Perez Jimenez, M. J., Bertoli, F., Raji, H., Lam, A., Bosch, M., Weissleder, C., Nemazanyy, I., Kalb, S., Hirschberg, I., Brunetti, D., Heckenbach, I., Scheibye-Knudsen, M., Deleidi, M.
10.1101/2024.09.03.610925 — Posted: 2024-09-03
CHCHD2 mutant mice display mitochondrial protein accumulation and disrupted energy metabolism
Liao, S.-C., Kano, K., Phanse, S., Nguyen, M., Margolis, E. B., Fu, Y., Meng, J., Moutaoufik, M. T., Chatterton, Z., Aoki, H., Simms, J., Hsieh, I., Suteja, F., Sei, Y., Huang, E. J., McAvoy, K., Manfredi, G., Halliday, G., Babu, M., Nakamura, K.
10.1101/2024.08.30.610586 — Posted: 2024-09-01
Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery
Adriaenssens, E., Schaar, S., Cooke, A. S. I., Stuke, J. F. M., Sawa-Makarska, J., Nguyen, T. N., Ren, X., Schuschnig, M., Romanov, J., Khuu, G., Lazarou, M., Hummer, G., Hurley, J. H., Martens, S.
10.1101/2024.08.28.609967 — Posted: 2024-08-28
Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila
Kaempf, N., Valadas, J. D. S., Robberechts, P., Schoovaerts, N., Praschberger, R., Ortega, A., Kilic, A., Chabot, D., Pech, U., Kuenen, S., Vilain, S., Baz, E.-S., Singh, J., Davis, J., Liu, S., Verstreken, P.
10.1101/2024.08.27.609924 — Posted: 2024-08-27

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