Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

Serum neurofilament light as a biomarker for prognosis in patients with newly diagnosed Parkinson disease
Vijiaratnam, N., Lawton, M., Heslegrave, A., Guo, T., Tan, M. M., Jabbari, E., Real, R., Woodside, J., Grosset, K. A., Chelban, V., Athauda, D., Girges, C., Barker, R. A., Hardy, J., Wood, N., Houlden, H., Williams, N., Ben-Shlomo, Y., Zetterberg, H., Grosset, D. G., Foltynie, T., Morris, H.
10.1101/2021.11.01.21265751 — Posted: 2021-11-02
Motor learning selectively strengthens cortical and striatal synapses of motor engram neurons
Hwang, F.-J., Roth, R. H., Wu, Y.-W., Sun, Y., Liu, Y., Ding, J. B.
10.1101/2021.10.28.466357 — Posted: 2021-10-28
Constitutive nuclear accumulation of endogenous alpha-synuclein in mice causes motor dysfunction and cortical atrophy, independent of protein aggregation.
Geertsma, H. M., Suk, T. R., Ricke, K. M., Horsthuis, K., Parmasad, J.-L. A., Fisk, Z., Callaghan, S. M., Rousseaux, M. W. C.
10.1101/2021.10.13.464123 — Posted: 2021-10-14
Progranulin deficiency results in reduced bis(monoacylglycero)phosphate (BMP) levels and gangliosidosis
Boland, S., Swarup, S., Ambaw, Y. A., Richards, R. C., Fischer, A. W., Singh, S., Aggarwal, G., Spina, S., Nana, A. L., Grinberg, L. T., Seeley, W. W., Surma, M. A., Klose, C., Paulo, J. A., Nguyen, A. D., Harper, J. W., Walther, T. C., Farese, R. V.
10.1101/2021.09.30.461806 — Posted: 2021-09-30
The activities of LRRK2 and GCase are positively correlated in clinical biospecimens and experimental models of Parkinson's disease
Kedariti, M., Frattini, E., Baden, P., Cogo, S., Civiero, L., Ziviani, E., Aureli, M., Kaganovich, A., Cookson, M. R., Stefanis, L. R., Surface, M., Deleidi, M., Di Fonzo, A., Alcalay, R. N., Rideout, H., Greggio, E., Plotegher, N.
10.1101/2021.09.27.461935 — Posted: 2021-09-28
Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse
Roosen, D. A., Landeck, N., Bonet-Ponce, L., Kluss, J., Conti, M., Smith, N., Saez-Atienzar, S., Ding, J., Beilina, A., Kumaran, R., Kaganovich, A., du Hoffmann, J., Williamson, C., Gershlick, D. C., Sampieri, L., Bleck, C. K. E., Liu, C., Bonifacino, J. S., Li, Y., Lewis, P. A., Cookson, M. R.
10.1101/830802 — Posted: 2021-09-16
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases
Waschbüsch, D., Berndsen, K., Lis, P., Knebel, A., Lam, Y. P., Alessi, D. R., Khan, A. R.
10.1101/2021.02.17.431620 — Posted: 2021-08-22
Subcellular and regional localization of mRNA translation in midbrain dopamine neurons
Hobson, B. D., Kong, L., Angelo, M. F., Lieberman, O. J., Mosharov, E. V., Herzog, E., Sulzer, D., Sims, P. A.
10.1101/2021.07.30.454065 — Posted: 2021-08-01
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson's disease at Chr16q11.2 and on the MAPT H1 allele
Soutar, M., Melandri, D., O'Callaghan, B., Annuario, E., Monaghan, A., Welsh, N., D'Sa, K., Guelfi, S., Zhang, D., Pittman, A., Trabzuni, D., Pan, K., Kia, D. A., Bictash, M., Gandhi, S., Houlden, H., Cookson, M. R., Wood, N., Singleton, A., Hardy, J., Whiting, P., Blauwendraat, C., Whitworth, A., Manzoni, C., Ryten, M., Lewis, P., Plun-Favreau, H.
10.1101/2020.01.06.896241 — Posted: 2021-07-30
Evaluation Of The Rims2 Locus As A Risk Locus For Parkinson's Disease Dementia
Tan, M., Real, R., Lawton, M., Bresner, C., Kanavou, S., Fotynie, T., Wood, N., Nalls, M. A., Williams, N., Ben-Shlomo, Y., Huw, M., Grosset, D., Hardy, J., Shoai, M., Morris, H. R.
10.1101/2021.07.26.21261131 — Posted: 2021-07-29

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