Channel:  Aligning Science Across Parkinson's (ASAP)

449 Articles

Synaptic Location Is a Determinant of the Detrimental Effects of alpha-Synuclein Pathology to Glutamatergic Transmission in the Basolateral Amygdala
Chen, L., Nagaraja, C., Daniels, S., Fisk, Z. A., Dvorak, R., Meyerdirk, L., Steiner, J. A., Galvis, M. L. E., Henderson, M., Rousseaux, M., Brundin, P., Chu, H.-y.
10.1101/2022.02.20.481207 — Posted: 2022-06-30
A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice
Abdel-Haq, R., Schlachetzki, J. C. M., Boktor, J. C., Cantu-Jungles, T. M., Thron, T., Zhang, M., Bostick, J. W., Khazaei, T., Chilakala, S., Morais, L. H., Humphrey, G., Keshavarzian, A., Katz, J. E., Thomson, M., Knight, R., Gradinaru, V., Hamaker, B. R., Glass, C. K., Mazmanian, S. K.
10.1101/2022.06.27.497828 — Posted: 2022-06-30
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
Harding, O., Holzbaur, E. L. F.
10.1101/2022.06.21.496850 — Posted: 2022-06-22
Dopaminergic axons track somatic signaling in behaving mice
Azcorra, M., Gaertner, Z., Davidson, C., Ramakrishnan, C., Fenno, L., Kim, Y. S., Deisseroth, K., Awatramani, R., Dombeck, D. A.
10.1101/2022.06.20.496872 — Posted: 2022-06-22
Metagenomics of Parkinson's disease implicates the gut microbiome in multiple disease mechanisms
Wallen, Z. D., Demirkan, A., Twa, G., Cohen, G., Dean, M. N., Standaert, D. G., Sampson, T., Payami, H.
10.1101/2022.06.08.495316 — Posted: 2022-06-12
Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
Choi, M. L., Chappard, A., Singh, B. P., Maclachlan, C., Rodrigues, M., Fedotova, E., Berezhnov, A., De, S., Peddie, C., Athauda, D., Virdi, G. S., Zhang, W., Evans, J. R., Wernick, A., Zanjani, Z., Angelova, P. R., Esteras, N., Andrey, A., Morris, K., Jeacock, K., Tosatto, L., Little, D., Gissen, P., Collinson, L., Clarke, D. J., Kunath, T., Klenerman, D., Abramov, A. Y., Horrocks, M. H., Gandhi, S.
10.1101/2022.06.07.494932 — Posted: 2022-06-09
The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines.
Smith, L. J., Bolsinger, M. M., Chau, K.-Y., Gegg, M. E., Schapira, A. H. V.
10.1101/2022.06.01.494130 — Posted: 2022-06-01
Basal Ganglia Neurons in Healthy and Parkinsonian Primates Generate Recurring Sequences of Spikes
Galvan, A., Wichmann, T.
10.1101/2022.05.25.493476 — Posted: 2022-05-26
Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia
Real, R., Martinez-Carrasco, A., Reynolds, R. H., Lawton, M. A., Tan, M. M. X., Shoai, M., Corvol, J.-C., Ryten, M., Bresner, C., Hubbard, L., Brice, A., Lesage, S., Faouzi, J., Elbaz, A., Artaud, F., Williams, N., Hu, M. T. M., Ben-Shlomo, Y., Grosset, D. G., Hardy, J., Morris, H. R.
10.1101/2022.05.23.22275465 — Posted: 2022-05-25
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson's disease data
Leonard, H. L., Murtadha, R., Martinez-Carrasco, A., Muller-Nedebock, A., Gil-Martinez, A.-L., Illarionova, A., Moore, A., Bustos, B. I., Jadhav, B., Huxford, B., Storm, C., Towns, C., Vitale, D., Chetty, D., Yu, E., Jama, F., Grenn, F. P., Salazar, G., Rateau, G., Iwaki, H., Elsayed, I., Foote, I., van Rensburg, Z. J., Kim, J. J., Yuan, J., Lake, J., Brolin, K., Senkevich, K., Wu, L., Tan, M. M. X., Perinan, M. T., Makarious, M. B., Ta, M., Pillay, N. S., Betancor, O. L., Reyes-Perez, P. R., Jerez, P. A., Saini, P., al-Ouran, R., Sivakumar, R., Real, R., Reynolds, R. H., Hu, R., Abrahams, S.
10.1101/2022.05.04.490670 — Posted: 2022-05-10

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