Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

Metagenomics of Parkinson's disease implicates the gut microbiome in multiple disease mechanisms
Wallen, Z. D., Demirkan, A., Twa, G., Cohen, G., Dean, M. N., Standaert, D. G., Sampson, T., Payami, H.
10.1101/2022.06.08.495316 — Posted: 2022-06-12
Structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
Choi, M. L., Chappard, A., Singh, B. P., Maclachlan, C., Rodrigues, M., Fedotova, E., Berezhnov, A., De, S., Peddie, C., Athauda, D., Virdi, G. S., Zhang, W., Evans, J. R., Wernick, A., Zanjani, Z., Angelova, P. R., Esteras, N., Andrey, A., Morris, K., Jeacock, K., Tosatto, L., Little, D., Gissen, P., Collinson, L., Clarke, D. J., Kunath, T., Klenerman, D., Abramov, A. Y., Horrocks, M. H., Gandhi, S.
10.1101/2022.06.07.494932 — Posted: 2022-06-09
The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines.
Smith, L. J., Bolsinger, M. M., Chau, K.-Y., Gegg, M. E., Schapira, A. H. V.
10.1101/2022.06.01.494130 — Posted: 2022-06-01
Basal Ganglia Neurons in Healthy and Parkinsonian Primates Generate Recurring Sequences of Spikes
Galvan, A., Wichmann, T.
10.1101/2022.05.25.493476 — Posted: 2022-05-26
Association between the LRP1B and APOE loci and the development of Parkinson's disease dementia
Real, R., Martinez-Carrasco, A., Reynolds, R. H., Lawton, M. A., Tan, M. M. X., Shoai, M., Corvol, J.-C., Ryten, M., Bresner, C., Hubbard, L., Brice, A., Lesage, S., Faouzi, J., Elbaz, A., Artaud, F., Williams, N., Hu, M. T. M., Ben-Shlomo, Y., Grosset, D. G., Hardy, J., Morris, H. R.
10.1101/2022.05.23.22275465 — Posted: 2022-05-25
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson's disease data
Leonard, H. L., Murtadha, R., Martinez-Carrasco, A., Muller-Nedebock, A., Gil-Martinez, A.-L., Illarionova, A., Moore, A., Bustos, B. I., Jadhav, B., Huxford, B., Storm, C., Towns, C., Vitale, D., Chetty, D., Yu, E., Jama, F., Grenn, F. P., Salazar, G., Rateau, G., Iwaki, H., Elsayed, I., Foote, I., van Rensburg, Z. J., Kim, J. J., Yuan, J., Lake, J., Brolin, K., Senkevich, K., Wu, L., Tan, M. M. X., Perinan, M. T., Makarious, M. B., Ta, M., Pillay, N. S., Betancor, O. L., Reyes-Perez, P. R., Jerez, P. A., Saini, P., al-Ouran, R., Sivakumar, R., Real, R., Reynolds, R. H., Hu, R., Abrahams, S.
10.1101/2022.05.04.490670 — Posted: 2022-05-10
Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
Jensen, L. E., Rao, S., Schuschnig, M., Cada, A. K., Martens, S., Hummer, G., Hurley, J. H.
10.1101/2022.05.03.490522 — Posted: 2022-05-04
In situ structural analysis reveals membrane shape transitions during autophagosome formation
Bieber, A., Capitanio, C., Erdmann, P. S., Fiedler, F., Beck, F., Lee, C.-W., Li, D., Hummer, G., Schulman, B., Baumeister, W., Wilfling, F.
10.1101/2022.05.02.490291 — Posted: 2022-05-02
Structural basis of human LRRK2 membrane recruitment and activation
Zhu, H., Tonelli, F., Alessi, D. R., Sun, J.
10.1101/2022.04.26.489605 — Posted: 2022-04-26
Diabetes and neuroaxonal damage in Parkinson's disease
Vijiaratnam, N., Lawton, M., Real, R., Heslegrave, A., Guo, T., Athauda, D., Gandhi, S., Girges, C., ben-shlomo, Y., Zetterberg, H., Grosset, D., Morris, H., Foltynie, T.
10.1101/2022.04.19.22274027 — Posted: 2022-04-21

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