Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

Cell type directed design of synthetic enhancers
Taskiran, I. I., Spanier, K. I., Christiaens, V., Mauduit, D., Aerts, S.
10.1101/2022.07.26.501466 — Posted: 2022-07-27
Integrated multi-cohort analysis of the Parkinson's disease gut metagenome
Boktor, J. C., Sharon, G., Verhagen Metman, L. A., Hall, D. A., Engen, P. A., Zreloff, Z., Hakim, D. J., Bostick, J. W., Ousey, J., Lange, D., Humphrey, G., Ackermann, G., Carlin, M., Knight, R., Keshavarzian, A., Mazmanian, S. K.
10.1101/2022.07.20.500694 — Posted: 2022-07-21
Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
Ren, X., Nguyen, T. N., Lam, W. K., Buffalo, C. Z., Lazarou, M., Yokom, A. L., Hurley, J. H.
10.1101/2022.07.12.499634 — Posted: 2022-07-13
Structural and functional landscape of α-synuclein fibril conformations amplified from cerebrospinal fluid
Sokratian, A., Zhou, Y., Xu, E., Viverette, E., Dillard, L., Yuan, Y., Li, J., Matarangas, A., Bouvette, J., Borgnia, M. J., Bartesaghi, A., West, A.
10.1101/2022.07.13.499896 — Posted: 2022-07-13
Mitoguardin-2 is a lipid transporter and its lipid transfer ability is required for function
Hong, Z., Adlakha, J., Guinn, E., Giska, F., Gupta, K., Melia, T., Reinisch, K. M.
10.1101/2022.07.08.499339 — Posted: 2022-07-09
DOPA pheomelanin is increased in nigral neuromelanin of Parkinson's disease and it exacerbates alpha-synuclein neurotoxicity
Cai, W., Wakamatsu, K., Zucca, F., Yang, K., Mohamadzadehhonarvar, N., Srivastava, P., Holly, G., Casella, L., Ito, S., Zecca, L., Chen, X.
10.1101/2022.06.30.22277063 — Posted: 2022-07-03
Synaptic Location Is a Determinant of the Detrimental Effects of alpha-Synuclein Pathology to Glutamatergic Transmission in the Basolateral Amygdala
Chen, L., Nagaraja, C., Daniels, S., Fisk, Z. A., Dvorak, R., Meyerdirk, L., Steiner, J. A., Galvis, M. L. E., Henderson, M., Rousseaux, M., Brundin, P., Chu, H.-y.
10.1101/2022.02.20.481207 — Posted: 2022-06-30
A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice
Abdel-Haq, R., Schlachetzki, J. C. M., Boktor, J. C., Cantu-Jungles, T. M., Thron, T., Zhang, M., Bostick, J. W., Khazaei, T., Chilakala, S., Morais, L. H., Humphrey, G., Keshavarzian, A., Katz, J. E., Thomson, M., Knight, R., Gradinaru, V., Hamaker, B. R., Glass, C. K., Mazmanian, S. K.
10.1101/2022.06.27.497828 — Posted: 2022-06-30
Dopaminergic axons track somatic signaling in behaving mice
Azcorra, M., Gaertner, Z., Davidson, C., Ramakrishnan, C., Fenno, L., Kim, Y. S., Deisseroth, K., Awatramani, R., Dombeck, D. A.
10.1101/2022.06.20.496872 — Posted: 2022-06-22
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
Harding, O., Holzbaur, E. L. F.
10.1101/2022.06.21.496850 — Posted: 2022-06-22

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