Channel:  Harvard Program in Therapeutic Sciences

119 Articles

Unifying the Identification of Biomedical Entities with the Bioregistry
Hoyt, C. T., Balk, M., Callahan, T. J., Domingo-Fernandez, D., Haendel, M. A., Hegde, H. B., Himmelstein, D. S., Karis, K., Kunze, J., Lubiana, T., Matentzoglu, N., McMurry, J., Moxon, S., Mungall, C. J., Rutz, A., Unni, D. R., Willighagen, E., Winston, D., Gyori, B. M.
10.1101/2022.07.08.499378 — Posted: 2022-10-22
Multi range ERK responses shape the proliferative trajectory of single cells following oncogene induced senescence
Chen, J.-Y., Hug, C., Reyes, J., Tian, C., Gerosa, L., Fröhlich, F., Ponsioen, B., Snippert, H. J. G., Spencer, S. L., Jambhekar, A., Sorger, P. K., Lahav, G.
10.1101/2022.10.06.511142 — Posted: 2022-10-07
Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer
Lin, J.-R., Wang, S., Coy, S., Chen, Y.-A., Yapp, C., Tyler, M. A., Nariya, M., Heiser, C. N., Lau, K., Santagata, S., Sorger, P. K.
10.1101/2021.03.31.437984 — Posted: 2022-09-28
Paired evaluation defines performance landscapes for machine learning models
Nariya, M. K., Mills, C. E., Sorger, P. K., Sokolov, A.
10.1101/2022.09.07.507020 — Posted: 2022-09-12
Automated assembly of molecular mechanisms at scale from text mining and curated databases
Bachman, J. A., Gyori, B. M., Sorger, P. K.
10.1101/2022.08.30.505688 — Posted: 2022-08-31
Resolving deleterious and near-neutral effects requires different pooled fitness assay designs
Limdi, A., Baym, M.
10.1101/2022.08.19.504558 — Posted: 2022-08-20
Lymphocyte networks are dynamic cellular communities in the immunoregulatory landscape of lung adenocarcinoma
Gaglia, G., Burger, M., Ritch, C. C., Rammos, D., Dai, Y., Crossland, G. E., Tavana, S. Z., Warchol, S., Jaeger, A. M., Naranjo, S., Coy, S., Johnson, A., Krueger, R., Lin, J.-R., Pfister, H., Sorger, P. K., Jacks, T., Santagata, S.
10.1101/2022.08.11.503237 — Posted: 2022-08-13
Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data
Warchol, S., Krueger, R., Nirmal, A. J., Gaglia, G., Jessup, J., Ritch, C. C., Hoffer, J., Muhlich, J. L., Burger, M., Jacks, T. L., Santagata, S., Sorger, P. K., Pfister, H.
10.1101/2022.05.09.490039 — Posted: 2022-08-11
Efficient computation of adjoint sensitivities at steady-state in ODE models of biochemical reaction networks
Lakrisenko, P., Stapor, P., Grein, S., Paszkowski, Łukasz, Pathirana, D., Fröhlich, F., Lines, G. T., Weindl, D., Hasenauer, J.
10.1101/2022.08.08.503176 — Posted: 2022-08-11
Swapped genetic code blocks viral infections and gene transfer
Nyerges, A., Vinke, S., Flynn, R., Owen, S. V., Rand, E. A., Budnik, B., Keen, E., Narasimhan, K., Marchand, J. A., Baas-Thomas, M., Liu, M., Chen, K., Chiappino-Pepe, A., Hu, F., Baym, M., Church, G. M.
10.1101/2022.07.08.499367 — Posted: 2022-07-10

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