Channel:  Harvard Program in Therapeutic Sciences

119 Articles

Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity
Inde, Z., Yapp, C., Joshi, G. N., Spetz, J., Fraser, C., Deskin, B., Ghelfi, E., Sodhi, C., Hackam, D., Kobzik, L., Croker, B., Brownfield, D., Jia, H., Sarosiek, K. A.
10.1101/2020.09.13.276923 — Posted: 2020-09-13
Online narrative guides for illuminating tissue atlas data and digital pathology images
Rashid, R., Chen, Y.-A., Hoffer, J., Muhlich, J. L., Lin, J.-R., Krueger, R., Pfister, H., Mitchell, R., Santagata, S., Sorger, P.
10.1101/2020.03.27.001834 — Posted: 2020-08-19
Time-resolved proteomic profiling of the ciliary Hedgehog response reveals that GPR161 and PKA undergo regulated co-exit from cilia
May, E. A., Kalocsay, M., Galtier D'Auriac, I., Gygi, S. P., Nachury, M. V., Mick, D. U.
10.1101/2020.07.29.225797 — Posted: 2020-07-29
Simplitigs as an efficient and scalable representation of de Bruijn graphs
Brinda, K., Baym, M., Kucherov, G.
10.1101/2020.01.12.903443 — Posted: 2020-06-21
Orphan nuclear receptor COUP-TFII drives the myofibroblast metabolic shift leading to fibrosis
Li, L., Galichon, P., Xiao, X., Figueroa-Ramirez, A. C., Tamayo, D., Lee, J. J., Kalocsay, M., Gonzalez-Sanchez, D., Chancay, M. S., McCracken, K., Lemos, D., Lee, N., Ichimura, T., Mori, Y., Valerius, M. T., Sun, X., Edelman, E. R., Bonventre, J. V.
10.1101/2020.06.05.135889 — Posted: 2020-06-05
Machine Learning Identifies Novel Candidates for DrugRepurposing in Alzheimer's Disease
Rodriguez, S., Hug, C., Todorov, P., Moret, N., Boswell, S. A., Evans, K., Zhou, G., Johnson, N. T., Hyman, B., Sorger, P., Albers, M. W., Sokolov, A.
10.1101/2020.05.15.098749 — Posted: 2020-05-16
Channel Embedding for Informative Protein Identification from Highly Multiplexed Images
Magid, S. A., Jang, W.-D., Schapiro, D., Wei, D., Tompkin, J., Sorger, P. K., Pfister, H.
10.1101/2020.03.24.004085 — Posted: 2020-03-25
Comparing the efficacy of cancer therapies between subgroups in basket trials
Palmer, A. C., Plana, D., Sorger, P.
10.1101/401620 — Posted: 2020-01-14
Biomarker-guided treatment strategies for ovarian cancer identified from a heterogeneous panel of patient-derived tumor xenografts
Palmer, A. C., Plana, D., Gao, H., Korn, J. M., Yang, G., Green, J., Zhang, X., Velazquez, R., McLaughlin, M. E., Ruddy, D. A., Kowal, C., Goldovitz, J., Bullock, C., Rivera, S., Rakiec, D., Elliott, G., Fordjour, P., Meyer, R., Loo, A., Kurth, E., Engelman, J. A., Bitter, H., Sellers, W. R., Sorger, P. K., Williams, J. A.
10.1101/2020.01.08.898734 — Posted: 2020-01-13
The Kinase Chemogenomic Set (KCGS): An open science resource for kinase vulnerability identification
Wells, C. I., Al-Ali, H., Andrews, D. M., Asquith, C. R. M., Axtman, A. D., Chung, M., Dikic, I., Ebner, D., Elkins, J., Ettmayer, P., Fischer, C., Frederiksen, M., Gray, N. S., Hatch, S. B., Knapp, S., Lee, S., Lucking, U., Michaelides, M., Mills, C. E., Muller, S., Owen, D., Picado, A., Ramadan, K., Saikatendu, K. S., Schroder, M., Stolz, A., Tellechea, M., Treiber, D. K., Turunen, B. J., Vilar, S., Wang, J., Zuercher, W., Willson, T. M., Drewry, D. H.
10.1101/2019.12.22.886523 — Posted: 2019-12-23

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