Channel:  Aligning Science Across Parkinson's (ASAP)

403 Articles

CNV-Finder: Streamlining Copy Number Variation Discovery
Kuznetsov, N., Daida, K., Makarious, M. B., Al-Mubarak, B., Atterling Brolin, K., Malik, L., Kouam, C., Baker, B., Real, R., Step, K., Lange, L. M., Wu, L., Ostrozovicova, M., Andersh, K. M., Kung, P.-J., Mecheri, Y., Tay, Y.-W., Soundous Malek, B., Al Tassan, N., Teresa Perinan, M., Hong, S., Koretsky, M. J., Sargeant, L., Levine, K., Blauwendraat, C., Billingsley, K. J., Bandres-Ciga, S., Leonard, H. L., Bardien, S., Morris, H. R., Singleton, A. B., Nalls, M. A., Vitale, D., The Global Parkinson's Genetics Program
10.1101/2024.11.22.624040 — Posted: 2025-07-26
DIO-SPOTlight Transgenic Mouse to Functionally Monitor Protein Synthesis Regulated by the Integrated Stress Response
Oliver, M. L., Caffall, Z. F., Eatman, C. B., Faw, T. D., Calakos, N.
10.1101/2024.10.14.618312 — Posted: 2025-07-23
Enhanced beta power emerges from simulated parkinsonian primary motorcortex
Doherty, D. W., Chen, L., Smith, Y., Wichmann, T., Chu, H.-Y., Lytton, W. W.
10.1101/2024.05.23.595566 — Posted: 2025-07-20
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
Chen, S., Basiashvili, T., Hutchings, J., Murillo, M. S., Suarez, A. V., Xiong, E., Louro, J. A., Leschziner, A. E., Villa, E.
10.1101/2024.06.18.599606 — Posted: 2025-07-10
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex
Salazar, M. P. R., Kolanukuduru, S., Ramirez, V., Lyu, B., Manigault, G., Sejourne, G., Sesaki, H., Yu, G., Eroglu, C.
10.1101/2024.10.22.619706 — Posted: 2025-07-03
Characterizing Parkinson's Disease Clinical and Biomarker Interactions in REM Sleep Behavior Disorder
Reddy, V. L., Esposito, S., Renkl, E., Benyakoub, A., Mead, K., Chrysostoum, C., Patel, S., Seibyl, J. P., Huang, Y., Koo, B. B., Cedarbaum, J. M.
10.1101/2025.05.16.25327469 — Posted: 2025-06-23
Sub-second analysis of locomotor activity in Parkinsonian mice
Berezhnoi, D., Chehade, H. D., Simms, G., Chen, L., SIVANVAYAL NARASIMHAN, K. K., Dravid, S., Chu, H.-Y.
10.1101/2024.12.26.630411 — Posted: 2025-06-18
Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool
Bolen, M. L., Buendia, M., Shi, J., Staley, H., Kachergus, J. M., Efron, P. A., Park, G., Nagpal, R., Alvarez, S. D., Xue, Q.-S., McFarland, N. R., Zimmermann, E. M., Forsmark, C. E., Menees, K. B., Salas, A., Thompson, E. A., Tansey, M. G.
10.1101/2025.04.29.651228 — Posted: 2025-06-11
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease
Chocarro, J., Marana, S., Espelosin, M., Rico, A. J., Ariznabarreta, G., Lorenzo-Ramos, E., Ilarduya, M. M., Hernandez-Alcoceba, R., Chillon, M., Vila, M., Kordower, J., Schapira, A. H. V., Garcia-Osta, A., Cuadrado-Tejedor, M., Lanciego, J. L.
10.1101/2025.05.09.653000 — Posted: 2025-06-11
Internalized α-synuclein fibrils become truncated and resist degradation in neurons while glial cells rapidly degrade α-synuclein fibrils.
Karim, M. R., Tiegs, E., Gasparini, E., Schlichte, R., Vermilyea, S. C., Lee, M. K.
10.1101/2024.06.05.597615 — Posted: 2025-06-11

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