Channel:  Aligning Science Across Parkinson's (ASAP)

476 Articles

Striatal ensembles specify and control granular forelimb actions
Rodrigues-Vaz, I., Athalye, V. R., Peterka, D. S., Costa, R. M.
10.64898/2025.12.03.692128 — Posted: 2025-12-08
Elucidating an anterior cingulate circuit for self-initiated actions and rescue of Parkinsonian akinesia
Ulloa Severino, F., Lu, B., Kim, J., Friedman, A., Roshchina, M., Johnson, S., Bakhurin, K., Eroglu, C., Yin, H.
10.64898/2025.12.01.691607 — Posted: 2025-12-03
Tau, amyloid-beta and alpha-synuclein co-pathologies synergistically enhance neuroinflammation and neuropathology
Webster, J. M., Yang, Y.-T., Miller, A. T., Zane, A., Scholz, K., Stone, W. J., Corbin-Stein, N. J., Mudium, N., Won, W.-J., Stoll, A. C., Greathouse, K. M., Cooper, N. H., Long, L. F., Manuel, P. N., Herskowitz, J. H., Yacoubian, T. A., Tyrrell, D. J., Sandoval, I. M., Manfredsson, F. P., Kordower, J. H., Harms, A. S.
10.1101/2024.10.13.618101 — Posted: 2025-11-24
A Multimodal Atlas Reveals the Anatomical Distribution of Medium Spiny Neuron Subtypes and a Novel RGS6+ Population in the Primate Striatum
Abdelhady, G., Brull, O. R., He, J., Lin, M. K., Galvan, A., Pfenning, A. R., Bostan, A. C., Stauffer, W. R.
10.1101/2025.11.16.688724 — Posted: 2025-11-19
LRRK2 integrates Rab and GABARAP interactions to sense and respond to distinct lysosomal stresses
Clegg, D., Bentley-DeSousa, A., Roczniak-Ferguson, A., Ferguson, S. M.
10.1101/2025.11.19.689251 — Posted: 2025-11-19
Pathway and gates for ATG2A-mediated lipid transport in autophagy
Cabezudo, A. C., Holzer, E., Martens, S., Hummer, G.
10.1101/2025.11.16.688672 — Posted: 2025-11-16
Insights into the regulation of VPS13 family bridge-like lipid transfer proteins from the structure of VPS13C.
Li, D., Wang, X., Hu, B., Hao, H., Hamill, S., Li, Y., Chen, G., De Camilli, P., Reinisch, K.
10.1101/2025.11.10.687702 — Posted: 2025-11-11
Reconstitution of multistep recruitment of ULK1 to membranes in autophagy
Duan, Y., Lu, Y., Paul, S., Betz, J., Wilhelm, L. P., Cook, A. S. I., Ren, X., Adriaenssens, E., Martens, S., Ganley, I., Hummer, G., Hurley, J. H.
10.1101/2025.11.07.687251 — Posted: 2025-11-09
Parkinsons disease modeling in regenerative spiny mice (Acomys dimidiatus) captures key disease-relevant behavioral, histological, and molecular signatures
Dutta, S., Pang, M., Donahue, R. R., Chou, T.-F., Seifert, A. W., Gradinaru, V.
10.1101/2025.11.06.687049 — Posted: 2025-11-08
Introducing PIGMO, a novel PIGmented MOuse model of Parkinson's disease
Chocarro, J., Marana, S., Espelosin, M., Rico, A. J., Ariznabarreta, G., Lorenzo-Ramos, E., Ilarduya, M. M., Hernandez-Alcoceba, R., Chillon, M., Vila, M., Kordower, J., Schapira, A. H. V., Garcia-Osta, A., Cuadrado-Tejedor, M., Lanciego, J. L.
10.1101/2025.05.09.653000 — Posted: 2025-11-05

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