Channel:  Francis Crick Institute

1,137 Articles

LRRK2-dependent Rab GTPase phosphorylation in response to endolysosomal damage depends on macrophage differentiation
Herbst, S., Gutierrez, M. G.
10.1101/2020.10.02.323873 — Posted: 2020-10-02
Evaluating the fitness of PA/I38T-substituted influenza A viruses with reduced baloxavir susceptibility in a competitive mixtures ferret model
Lee, L. Y., Zhou, J., Koszalka, P., Frise, R., Farrukee, R., Baba, K., Miah, S., Shishido, T., Galiano, M., Hashimoto, T., Omoto, S., Uehara, T., Mifsud, E., Collinson, N., Kuhlbusch, K., Clinch, B., Wildum, S., Barclay, W. S., Hurt, A. C.
10.1101/2020.09.28.316620 — Posted: 2020-09-28
Dual-view oblique plane microscopy (dOPM)
Sparks, H., Dent, L., Bakal, C., Behrens, A., Salbreux, G., Dunsby, C.
10.1101/2020.09.24.311613 — Posted: 2020-09-25
Plasmodium berghei kinesin-5 associates with the spindle apparatus during cell division and is important for efficient production of infectious sporozoites
Zeeshan, M., Brady, D., Stanway, R. R., Moores, C., Holder, A. A., Tewari, R.
10.1101/2020.07.03.186031 — Posted: 2020-09-22
ImmunoCluster: A computational framework for the non-specialist to profile cellular heterogeneity in cytometry datasets
Opzoomer, J. W., Timms, J. A., Blighe, K., Mourikis, T. P., Chapuis, N., Bekoe, R., Kareemaghay, S., Nocerino, P., Apollonio, B., Ramsay, A. G., Tavassoli, M., Harrison, C., Ciccarelli, F., Parker, P., Fontenay, M., Barber, P., Arnold, J. N., Kordasti, S.
10.1101/2020.09.09.289033 — Posted: 2020-09-21
MICAL2 acts through Arp3B isoform-specific Arp2/3 complexes to destabilize branched actin networks
Galloni, C., Carra, D., Abella, J. V. G., Kjaer, S., Singaravelu, P., Barry, D. J., Kogata, N., Guerin, C., Blanchoin, L., Way, M.
10.1101/2020.09.21.306522 — Posted: 2020-09-21
Primary sex determination in chickens depends on DMRT1 dosage, but gonadal sex does not determine secondary sexual characteristics in adult birds
Ioannidis, J., Taylor, G., Zhao, D., Liu, L., Idoko-Akoh, A., Gong, D., Lovell-Badge, R., Guioli, S., McGrew, M., Clinton, M.
10.1101/2020.09.18.303040 — Posted: 2020-09-19
The eukaryotic replisome requires an additional helicase to disarm dormant replication origins
Hill, J., Eickhoff, P., Drury, L., Costa, A., Diffley, J.
10.1101/2020.09.17.301366 — Posted: 2020-09-17
Single-molecule measurements reveal that PARP1 condenses DNA by loop formation
Bell, N. A. W., Haynes, P. J., Brunner, K., Maia de Oliveira, T., Flocco, M., Hoogenboom, B. W., Molloy, J. E.
10.1101/2020.09.15.297887 — Posted: 2020-09-15
A two-site flexible clamp mechanism for RET-GDNF-GFRα1 assembly reveals both conformational adaptation and strict geometric spacing
Adams, S., Purkiss, A. G., Knowles, P. P., Nans, A., Briggs, D. C., Borg, A., Earl, C. P., Goodman, K. M., Nawrotek, A., Borg, A. J., McIntosh, P. B., Houghton, F. M., Kjaer, S., McDonald, N. Q.
10.1101/2020.09.13.286047 — Posted: 2020-09-13

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