Channel:  Francis Crick Institute

1,171 Articles

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Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization
Brown, A.-L., Wilkins, O. G., Keuss, M. J., Hill, S. E., Zanovello, M., Lee, W. C., Lee, F. C. Y., Masino, L., Qi, Y. A., Bryce-Smith, S., Bampton, A., Gatt, A., Phatnani, H., NYGC ALS Consortium, , Schiavo, G., Fisher, E. M. C., Raj, T., Secrier, M., Lashley, T., Ule, J., Buratti, E., Humphrey, J., Ward, M. E., Fratta, P.
10.1101/2021.04.02.438170 — Posted: 2021-04-04
Severity of SARS-CoV-2 infection as a function of the interferon landscape across the respiratory tract of COVID-19 patients.
Sposito, B., Broggi, A., Pandolfi, L., Crotta, S., Ferrarese, R., Sisti, S., Clementi, N., Ambrosi, A., Liu, E., Frangipane, V., Saracino, L., Marongiu, L., Facchini, F., Bottazzi, A., Fossali, T., Colombo, R., Clementi, M., Tagliabue, E., Pontiroli, A., Meloni, F., Wack, A., Mancini, N., Zanoni, I.
10.1101/2021.03.30.437173 — Posted: 2021-03-30
In vitro teratogenicity testing using a 3D, embryo-like gastruloid system
Mantziou, V., Baillie-Benson, P., Jaklin, M., Kustermann, S., Martinez Arias, A., Moris, N.
10.1101/2021.03.30.437698 — Posted: 2021-03-30
Biallelic mutations in cancer genomes reveal local mutational determinants
Demeulemeester, J., Dentro, S. C., Gerstung, M., Van Loo, P.
10.1101/2021.03.29.437407 — Posted: 2021-03-30
N-myristoyltransferase inhibition is synthetic lethal in MYC-deregulated cancers
Lueg, G. A., Faronato, M., Gorelik, A., Goya Grocin, A., Caamano-Gutierrez, E., Falciani, F., Solari, R., Carr, R., Bell, A. S., Bartlett, E., Hutton, J. A., Llorian-Sopena, M., Chakravarty, P., Brzezicha, B., Janz, M., Garnett, M. J., Calado, D. P., Tate, E. W.
10.1101/2021.03.20.436222 — Posted: 2021-03-20
HIV-1 requires capsid remodelling at the nuclear pore for nuclear entry and integration
Guedan, A., Donaldson, C. D., Cosnefroy, O., Taylor, I. A., Bishop, K. N.
10.1101/2021.03.18.436028 — Posted: 2021-03-18
Synchrony between daily rhythms of malaria parasites and hosts is driven by an essential amino acid
Prior, K. F., Middleton, B., Owolabi, A. T., Westwood, M. L., Holland, J., O'Donnell, A. J., Blackman, M. J., Skene, D. J., Reece, S. E.
10.1101/2020.08.24.264689 — Posted: 2021-03-17
A physical theory of movement in small animals
Loveless, J., Garner, A., Issa, A. R., Roberts, R. J. V., Webb, B., Prieto-Godino, L. L., Ohyama, T., Alonso, C.
10.1101/2020.08.25.266163 — Posted: 2021-03-16
Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation
Modic, M., los Mozos, I. R. d., Steinhauser, S., van Genderen, E., Schirge, S., Bergant, V., Ryan, J., Mulholland, C. B., Lee, F. C. Y., Faraway, R., Klobucar, T., Merl-Pham, J., Hauck, S. M., Drukker, M., Bultmann, S., Leonhardt, H., Lickert, H., Luscombe, N. M., ten Berge, D., Ule, J.
10.1101/2021.03.15.433780 — Posted: 2021-03-16
High Content and High Throughout Phenotypic Assay for the Hourly Resolution of the Malaria Parasite Erythrocytic Cycle
Bell, D., Ridewood, S., Patel, A. P., Lee, S. H., Chang, Y.-T., Deu, E.
10.1101/2021.03.15.434938 — Posted: 2021-03-15

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