Channel:  Aligning Science Across Parkinson's (ASAP)

bioRxiv posts many COVID19-related papers. A reminder: they have not been formally peer-reviewed and should not guide health-related behavior or be reported in the press as conclusive.

256 Articles

Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
Adriaenssens, E., Nguyen, T. N., Sawa-Makarska, J., Khuu, G., Schuschnig, M., Shoebridge, S., Watts, E. M., Csalyi, K. D., Padman, B. S., Lazarou, M., Martens, S.
10.1101/2023.09.25.559255 — Posted: 2023-09-25
A leaky gut dysregulates gene networks in the brain associated with immune activation, oxidative stress, and myelination in a mouse model of colitis
Boles, J. S., Krueger, M., Jernigan, J., Cole, C., Neighbarger, N., Huarte, O. U., Tansey, M. G.
10.1101/2023.08.10.552488 — Posted: 2023-08-13
Gut mucosal cells transfer alpha-synuclein to the vagus nerve
Chandra, R., Sokratian, A., Chavez, K. R., King, S., Swain, S. M., Snyder, J. C., West, A. B., Liddle, R. A.
10.1101/2023.08.14.553305 — Posted: 2023-09-05
Structure of LRRK1 and mechanisms of autoinhibition and activation
Reimer, J. M., Dickey, A. M., Lin, Y. X., Abrisch, R. G., Mathea, S., Chatterjee, D., Fay, E. J., Daugherty, M. D., Reck-Peterson, S. L., Leschziner, A. E.
10.1101/2022.11.22.517582 — Posted: 2022-12-02
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data
Chen, X., Sailer, C., Kammer, K.-M., Fuersch, J., Eisele, M. R., Sakata, E., Stengel, F.
10.1101/2022.02.03.478943 — Posted: 2022-02-03
Inhibition of Parkinsons Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
Leschziner, A. E., Sanz Murillo, M., Suarez, A. V., Dederer, V., Chatterjee, D., Louro, J. A., Knapp, S., Mathea, S.
10.1101/2023.09.07.556689 — Posted: 2023-09-09
Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation
Galvagnion, C., Cerri, S., Schapira, A. H. V., Blandini, F., Di Monte, D. A.
10.1101/2020.11.09.375048 — Posted: 2020-11-09
The GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines.
Smith, L. J., Bolsinger, M. M., Chau, K.-Y., Gegg, M. E., Schapira, A. H. V.
10.1101/2022.06.01.494130 — Posted: 2022-06-01
Phenotypic effect of GBA1 variants in individuals with and without Parkinson disease: the RAPSODI study
Toffoli, M., Chohan, H., Mullin, S., Jesuthasan, A., Yalkic, S., Koletsi, S., Menozzi, E., Rahal, S., Limbachiya, N., Loefflad, N., Higgins, A., Bestwick, J., Lucas-Del-Pozo, S., Fierli, F., Farbos, A., Mezabrovschi, R., Lee-Yin, C., Schrag, A., Moreno-Martinez, D., Hughes, D., Noyce, A., Colclough, K., Jeffries, A. R., Proukakis, C., Schapira, A. H.
10.1101/2023.07.25.23291637 — Posted: 2023-07-27
Reduction of a-synuclein aggregates by PIKfyve inhibition via TFEB-mediated lysosomal biogenesis in a Parkinson disease model
Lucas-Del-Pozo, S., Uras, G., Fierli, F., Lentini, V., Koletsi, S., Chau, K.-Y., Hughes, D., Schapira, A. H.
10.1101/2023.10.23.563557 — Posted: 2023-10-24

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