Channel:  Francis Crick Institute

1,271 Articles

Histidine exchange sustains LAT1 activity and proliferation in glutamine-addicted breast cancers.
Gjelaj, E., Driscoll, P., Mahmood, A., Tarrago-Celada, J., Kossifos, M., Sesay, S., MacRae, J. I., Yuneva, M.
10.64898/2026.04.15.716193 — Posted: 2026-04-19
Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
Wang, J., Davis, C., Kunzelmann, S., Maslen, S., Kelly, G., Skehel, M., Schreiber, A.
10.64898/2026.04.16.718395 — Posted: 2026-04-18
GROQ-seq Datasets Across Transcription Factors (LacI, RamR, VanR), T7 RNA Polymerase and TEV Protease
Spinner, A., Sreenivasan, S., McLellan, J. R., Ikonomova, S. P., Cortade, D. L., dOelsnitz, S., Sheldon, K., Vasilyeva, O. B., Alperovich, N. Y., Chadha, A., Nematollahi, L., Dhroso, A., Sisson, Z., Hudson, C. M., DeBenedictis, E., Kelly, P. J., Reider Apel, A., Ross, D., Baranowski, C.
10.64898/2026.04.15.718744 — Posted: 2026-04-18
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
Du-Harpur, X., Ganier, C., Mazin, P., Cheshire, C., Gabriel, J. A., Rashidghamat, E., Luscombe, N. M., Lynch, M. D., Watt, F. M.
10.1101/2025.11.11.682326 — Posted: 2026-04-17
The Alzheimer's disease neurodegenerative cascade reconstructed in human L2/3 excitatory neurons
Zielonka, M., Mallach, A., De Strooper, B., Fiers, M.
10.64898/2026.04.14.718430 — Posted: 2026-04-15
Nonlinear mixed-effect models and tailored parametrization schemes enables integration of single cell and bulk data
Wang, D., Froehlich, F., Stapor, P., Schaelte, Y., Huth, M., Eils, R., Kallenberger, S., Hasenauer, J.
10.64898/2026.04.06.716803 — Posted: 2026-04-09
CDKL5 phosphorylates neuronal ELAVL proteins to promote mRNA binding, protein synthesis and visual cortex development
Mihaylov, S. R., Lopes, A. T., Silvestre, M., Bianchini, G., Flynn, H. R., Huseynova, A., Strohbuecker, S., Griffith, L., Militti, C., Baltussen, L. L., Yuan, X., Morel, G., Claxton, S., Dempster, K., Lee, F. C. Y., Kanca, O., Köhn, M., Skehel, M., Ule, J., Iacaruso, F., Ultanir, S. K.
10.64898/2026.04.07.716766 — Posted: 2026-04-07
NucleoNet and DropNet: Generalist deep learning models for instance segmentation of nuclei and lipid droplets from electron microscopy images
Bhardwaj, A., Dell, C. W., Mikolaj, M. R., Spiers, H., Harned, A., Kuppusamy, B., Liu, P., Wei, D., Sterneck, E., Narayan, K.
10.64898/2026.04.02.713930 — Posted: 2026-04-05
BDNF Regulates Pituitary Stem Cell Engagement towards precursor state
Sochodolsky, K., Khetchoumian, K., Balsalobre, A., Feeley, R. M., Rice, M. E., Chakravarty, P., Lovell-Badge, R., Rizzoti, K., DROUIN, J.
10.64898/2026.04.02.716194 — Posted: 2026-04-04
Mycobacterium tuberculosis partitions the Krebs cycle under iron starvation
Serafini, A., Garza-Garcia, A., Sorze, D., de Carvalho, L. P. S., Manganelli, R.
10.1101/2025.05.12.653400 — Posted: 2026-04-04

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