Channel:  Francis Crick Institute

1,190 Articles

A systematic benchmark of Nanopore long read RNA sequencing for transcript level analysis in human cell lines
Chen, Y., Davidson, N., Wan, Y. K., Patel, H., Yao, F., Low, H. M., Hendra, C., Watten, L., Sim, A., Sawyer, C., Iakovleva, V., Lee, P. L., Xin, L., Ng, H. E. V., Loo, J. M., Ong, X., Ng, H. Q. A., Wang, J., Koh, W. Q. C., Poon, S. Y. P., Stanojevic, D., Tran, H.-D., Lim, K. H. E., Toh, S. Y., Ewels, P., Ng, H.-H., Iyer, N. G., Thiery, A., Chng, W. J., Chen, L., DasGupta, R., Sikic, M., Chan, Y.-S., Tan, B. O. P., Wan, Y., Tam, W. L., Yu, Q., Khor, C. C., Wuestefeld, T., Pratanwanich, P. N., Love, M. I., Goh, W. S. S., Ng, S., Oshlack, A., Goeke, J.
10.1101/2021.04.21.440736 — Posted: 2021-04-22
Early immune pressure imposed by tissue resident memory T cells sculpts tumour evolution in non-small cell lung cancer
Weeden, C. E., Gayevskiy, V., Trussart, M., Marceaux, C., Tubau Ribera, N., Batey, D., Teh, C. E., Mitchell, A. J., Antippa, P., Leong, T., Steinfort, D., Irving, L., Gordon, C. L., Swanton, C., Speed, T. P., Gray, D. H., Asselin-Labat, M.-L.
10.1101/2021.04.20.440373 — Posted: 2021-04-22
Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses
Banchenko, S., Krupp, F., Gotthold, C., Buerger, J., Graziadei, A., O' Reilly, F., Sinn, L., Ruda, O., Rappsilber, J., Spahn, C. M. T., Mielke, T., Taylor, I. A., Schwefel, D.
10.1101/2020.12.31.424931 — Posted: 2021-04-19
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture
Alvarez, E. G., Demeulemeester, J., Jolly, C., Garcia-Souto, D., Otero, P., Pequeno, A., Zamora, J., Tojo, M., Temes, J., Baez-Ortega, A., Rodriguez-Martin, B., Li, Y., Oitaben, A., Bruzos, A. L., Martinez-Fernandez, M., Haase, K., Santamarina, M., Zumalave, S., Abal, R., Rodriguez-Castro, J., Rodriguez-Casanova, A., Diaz-Lagares, A., Raine, K., Butler, A. P., Ono, A., Aikata, H., Chayama, K., Ueno, M., Hayami, S., Yamaue, H., Blanco, M. G., Forns, X., Rivas, C., Perez-del-Pulgar, S., Torres-Ruiz, R., Rodriguez Perales, S., Garaigorta, U., Nakagawa, H., Campbell, P. J., Van Loo, P., Tubio, J.
10.1101/2021.04.19.440412 — Posted: 2021-04-19
Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage.
Morini, E., Gao, D., Logan, E. M., Salani, M., Krauson, A. J., Chekuri, A., Chen, Y.-T., Ragavendran, A., Chakravarty, P., Erdin, S., Stortchevoi, A., Svejstrup, J. Q., Talkowski, M. E., Slaugenhaupt, S. A.
10.1101/2021.04.16.440179 — Posted: 2021-04-16
A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer
Lovell, S., Zhang, L., Kryza, T., Neodo, A., Bock, N., Williams, E. D., Engelsberger, E., Xu, C., Bakker, A. T., De Vita, E., Maneiro, M., Tanaka, R. J., Bevan, C. L., Clements, J. A., Tate, E. W.
10.1101/2021.04.15.439906 — Posted: 2021-04-15
Single-shot phase contrast microscopy using polarisation-resolved differential phase contrast
Kalita, R., Flanagan, W., Lightley, J., Kumar, S., Alexandrov, Y., Garcia, E., Hintze, M., Barkoulas, M., Dunsby, C., French, P. M. W.
10.1101/2021.04.14.437846 — Posted: 2021-04-14
Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features
Rayon, T., Maizels, R. J., Barrington, C., Briscoe, J.
10.1101/2021.04.12.439474 — Posted: 2021-04-12
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
McClure, A. W., Diffley, J.
10.1101/2021.04.09.439171 — Posted: 2021-04-10
Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis
Pereira, C., Arroyo-Martinez, G. A., Guo, M. Z., Kelly, E. R., Grive, K. J., Mahadevaiah, S. K., Sims, J., Faca, V. M., Tsai, C., Schiltz, C. J., Wit, N., Jacobs, H., Clark, N. L., Freire, R., Turner, J., Lyndaker, A. M., Brieno-Enriquez, M. A., Cohen, P. E., Smolka, M. B., Weiss, R. S.
10.1101/2021.04.09.439198 — Posted: 2021-04-10

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