Channel:  Francis Crick Institute

1,190 Articles

Early functional mismatch between breast cancer cells and their tumour microenvironment suppresses long term growth
Perdrix Rosell, A., Maiques, O., Chakravarty, P., Ombrato, L., Sanz-Moreno, V., Malanchi, I.
10.1101/2021.06.15.448466 — Posted: 2021-11-18
PPAR-delta acts as a metabolic master checkpoint for metastasis in pancreatic cancer
Parejo-Alonso, B., Barneda, D., Trabulo, S. M., Courtois, S., Compte-Sancerni, S., Ruiz-Canas, L., Zheng, Q., Tang, J., Chen, M., Guo, Z., Schmitz, U., Irun, P., Penin-Peyta, L., Crusz, S. M., Cano-Galiano, A., Lopez-Escalona, S., Jagust, P., Espiau-Romera, P., Yuneva, M., Lin, M.-L., Lanas, A., Sainz, B., Heeschen, C., Sancho, P.
10.1101/2021.11.15.468579 — Posted: 2021-11-16
PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma
D'Avola, A., Legrave, N., Tajan, M., Chakravarty, P., Shearer, R., King, H., Cheung, E., Clear, A., Gunawan, A., Zhang, L., James, L., MacRae, J., Gribben, J., Calado, D., Vousden, K., Riches, J.
10.1101/2021.11.11.468272 — Posted: 2021-11-12
The molecular evolution of spermatogenesis across mammals
Murat, F., Mbengue, N., Winge, S. B., Trefzer, T., Leushkin, E., Sepp, M., Cardoso-Moreira, M., Schmidt, J., Schneider, C., Mössinger, K., Brüning, T., Lamanna, F., Belles, M. R., Conrad, C., Kondova, I., Bontrop, R., Behr, R., Khaitovich, P., Pääbo, S., Marques-Bonet, T., Grützner, F., Almstrup, K., Schierup, M. H., Kaessmann, H.
10.1101/2021.11.08.467712 — Posted: 2021-11-08
DeepBacs: Bacterial image analysis using open-source deep learning approaches
Spahn, C., Laine, R. F., Pereira, P. M., Gomez-de-Mariscal, E., von Chamier, L., Conduit, M., Pinho, M. G., Holden, S., Jacquemet, G., Heilemann, M., Henriques, R.
10.1101/2021.11.03.467152 — Posted: 2021-11-03
N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing
Kliza, K. W., Song, W., Pinzuti, I., Schaubeck, S., Kunzelmann, S., Kuntin, D., Fornili, A., Pandini, A., Hofmann, K., Garnett, J., Stieglitz, B., Husnjak, K.
10.1101/2021.11.02.466974 — Posted: 2021-11-02
RNA sensing via LGP2 is essential for the induction of a type I IFN response in ADAR1 deficiency
Stok, J. E., Oosenbrug, T., ter Haar, L. R., Gravekamp, D., Bromley, C. P., Zelenay, S., Reis e Sousa, C., van der Veen, A. G.
10.1101/2021.10.27.465188 — Posted: 2021-10-28
The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC
Javitt, A., Shmueli, M. D., Kramer, M. P., Kolodziejczyk, A. A., Cohen, I. J., Kamer, I., Litchfield, K., Bab-Dinitz, E., Zadok, O., Neiens, V., Ulman, A., Radomir, L., Wolf-Levy, H., Eisenberg-Lerner, A., Kacen, A., Alon, M., Toste Rego, A., Stacher-Priehse, E., Linder, M., Koch, I., Bar, J., Swanton, C., Samuels, Y., Levin, Y., C. A. da Fonseca, P., Elinav, E., Friedman, N., Meiners, S., Merbl, Y.
10.1101/2021.10.24.464690 — Posted: 2021-10-24
In-vitro cellular reprogramming to model gonad development and its disorders
Gonen, N., Eozenou, C., Mitter, R., Bernardo, A., Chervova, A., Frachon, E., Commere, P.-H., Mazen, I., Gobaa, S., McElreavey, K., Lovell-Badge, R., Bashamboo, A.
10.1101/2021.10.22.465384 — Posted: 2021-10-24
ZELDA: a 3D Image Segmentation and Parent-Child relation plugin for microscopy image analysis in napari
D'Antuono, R., Pisignano, G.
10.1101/2021.10.24.465596 — Posted: 2021-10-24

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