Channel:  Francis Crick Institute

1,190 Articles

Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA.1 that likely impact Spike function
Martin, D. P., Lytras, S., Lucaci, A. G., Maier, W., Gruning, B., Shank, S. D., Weaver, S., MacLean, O. S., Orton, R. J., Lemey, P., Boni, M. F., Tegally, H., Harkins, G. W., Scheepers, C., Bhiman, J. N., Everatt, J., Amoako, D. G., San, J. E., Giandhari, J., Sigal, A., NGS-SA, , Williamson, C., Hsiao, N.-y., von Gottberg, A., De Klerk, A., Shafer, R. W., Robertson, D. L., Wilkinson, R. J., Sewell, B. T., Lessells, R., Nekrutenko, A., Greaney, A. J., Starr, T. N., Bloom, J. D., Murrell, B., Wilkinson, E., Gupta, R. K., de Oliveira, T., Kosakovsky Pond, S. L.
10.1101/2022.01.14.476382 — Posted: 2022-01-18
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
Boumelha, J., de Carne Trecesson, S., Law, E., Romero-Clavijo, P., Coelho, M., Ng, K., Mugarza, E., Moore, C., Rana, S., Caswell, D., Murillo, M., Hancock, D., Argyris, P., Brown, W., Durfee, C., Larson, L., Vogel, R., Alejandro Suarez-Bonnet, A., Priestnall, S., East, P., Ross, S., Kassiotis, G., Molina-Arcas, M., Swanton, C., Harris, R., Downward, J.
10.1101/2020.12.22.423126 — Posted: 2022-01-17
Unraveling membrane properties at the organelle-level with LipidDyn
Scrima, S., Tiberti, M., Campo, A., Corcelle-Termeau, E., Judith, D., Moller Foged, M., Bundgaard Clemmensen, K. K., Tooze, S., Jäättelä, M., Maeda, K., Lambrughi, M., Papaleo, E.
10.1101/2022.01.04.474788 — Posted: 2022-01-14
Role of Yap1 in adult neural stem cell activation
Berninger, B., Fan, W., Jurado-Arjona, J., Alanis-Lobato, G., Peron, S., Berger, C., Andrade-Navarro, M. A., Falk, S.
10.1101/2022.01.12.475985 — Posted: 2022-01-13
Interactions between influenza A virus nucleoprotein and gene segment UTRs facilitate selective modulation of viral gene expression
Diefenbacher, M., Tan, T. J. C., Bauer, D. L. V., Stadtmueller, B., Wu, N. C., Brooke, C. B.
10.1101/2022.01.09.475567 — Posted: 2022-01-11
Endosomal structure and APP biology are not altered in preclinical cellular models of Down syndrome
Cannavo, C., Cleverley, K., Maduro, C., Mumford, P., Moulding, D., Fisher, E., Wiseman, F. K.
10.1101/2021.12.30.474570 — Posted: 2021-12-30
Regulation of KHNYN antiviral activity by the extended di-KH domain and nucleo-cytoplasmic trafficking
Lista, M. J., Galao, R. P., Ficarelli, M., Kmiec, D., Wilson, H., Winstone, H., Morris, E. R., Mischo, H. E., Wanford, J., Youle, R., Odendall, C., Taylor, I. A., Neil, S. J., Swanson, C.
10.1101/2021.12.22.473955 — Posted: 2021-12-24
Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria
Al Rawi, S., Simpson, L., McDonald, N. Q., Chernuha, V., Elpeleg, O., Zeviani, M. Q., Barker, R. A., Spiegel, R., Laman, H.
10.1101/2021.12.22.473884 — Posted: 2021-12-23
Cellular development and evolution of the mammalian cerebellum
Sepp, M., Leiss, K., Sarropoulos, I., Murat, F., Okonechnikov, K., Joshi, P., Leushkin, E., Mbengue, N., Schneider, C., Schmidt, J., Trost, N., Spaenig, L., Giere, P., Khaitovich, P., Lisgo, S., Palkovits, M., Kutscher, L. M., Anders, S., Cardoso-Moreira, M., Pfister, S. M., Kaessmann, H.
10.1101/2021.12.20.473443 — Posted: 2021-12-21
Visualizing pyrazinamide action by live single cell imaging of phagosome acidification and Mycobacterium tuberculosis pH homeostasis
Santucci, P., Aylan, B., Botella, L., Bernard, E. M., Bussi, C., Pellegrino, E., Athanasiadi, N., Gutierrez, M. G.
10.1101/2021.12.20.473466 — Posted: 2021-12-20

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