Channel:  Francis Crick Institute

1,153 Articles

A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression
Gaggioli, M. R., Jones, A. G., Panagi, I., Washington, E. J., Loney, R. E., Muench, J. H., Brennan, R. G., Thurston, T. L. M., Ko, D. C.
10.1101/2024.02.14.580367 — Posted: 2024-02-14
Optical tweezers reveal that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium-falciparum merozoite-erythrocyte attachment
Kals, E., Kals, M., Lees, R. A., Introini, V., Kemp, A., Silvester, E., Collins, C. R., Umrekar, T., Kotar, J., Cicuta, P., Rayner, J. C.
10.1101/2024.02.13.580055 — Posted: 2024-02-13
Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications
Matwani, K., Cornish, J., DeBenedictis, E. A., Heller, G. T.
10.1101/2024.02.12.579991 — Posted: 2024-02-12
Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response
Jones, R. A., Cooper, F., Kelly, G., Barry, D., Renshaw, M. J., Sapkota, G., Smith, J. C.
10.1101/2024.02.10.579757 — Posted: 2024-02-12
Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia
Rahman, S., Bloye, G., Farah, N., Demeulemeester, J., Costa, J. R., O'Connor, D., Pocock, R., Turna, A., Wang, L., Lee, S., Fielding, A. K., Roels, J., Jaksik, R., Dawidowska, M., Vlierberghe, P. V., Hadjur, S., Hughes, J. R., Davies, J. O. J., Gutierrez, A., Kelliher, M. A., Loo, P. V., Dawson, M. A., Mansour, M. R.
10.1101/2024.02.06.579027 — Posted: 2024-02-08
Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1
Griffith, S., Muir, L., Suchanek, O., Hope, J., Pade, C., Gibbons, J. M., Tuong, Z. K., Fung, A., Touizer, E., Rees-Spear, C., Nans, A., Roustan, C., Alguel, Y., Fink, D., Orkin, C., Deayton, J., Anderson, J., Gupta, R. K., Doores, K. J., Cherepanov, P., McKnight, A., Clatworthy, M., McCoy, L. E.
10.1101/2024.02.05.578789 — Posted: 2024-02-06
Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.
Koussis, K., Haase, S., Withers-Martinez, C., Flynn, H. R., Kunzelmann, S., Christodoulou, E., Ibrahim, F., Skehel, M., Baker, D. A., Blackman, M. J.
10.1101/2024.02.04.578801 — Posted: 2024-02-04
Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst
Simon, C. S., McCarthy, A., Woods, L., Staneva, D., Huang, Q., Linneberg-Agerholm, M., Faulkner, A., Papathanasiou, A., Elder, K., Snell, P., Christie, L., Garcia, P., Shaikly, V., Taranissi, M., Choudhary, M., Herbert, M., Brickman, J. M., Niakan, K. K.
10.1101/2024.02.01.578414 — Posted: 2024-02-04
Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size
Chu, L.-Y., Stedman, D., Gannon, J., Cox, S., Pobegalov, G., Molodtsov, M.
10.1101/2024.02.01.578443 — Posted: 2024-02-02
m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation
Klein, P., Harley, J., Crook, H., Serna, S. E., Petric-Howe, M., Roumeliotis, T. I., Choudhary, J. S., Chakrabarti, A. M., Luisier, R., Patani, R., Ramos, A.
10.1101/2023.09.12.557394 — Posted: 2024-02-02

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