Channel:  Francis Crick Institute

1,153 Articles

Cell heterogeneity and fate bistability drive tissue patterning during intestinal regeneration
Schwayer, C., Barbiero, S., Brückner, D. B., Baader, C., Repina, N. A., Diaz, O. E., Meylan, L. C., Kalck, V., Suppinger, S., Yang, Q., Schnabl, J., Kilik, U., Camp, J. G., Stockinger, B., Bühler, M., Stadler, M. B., Hannezo, E., Liberali, P.
10.1101/2025.01.14.632683 — Posted: 2025-01-15
Unlocking the Secrets of NSP3: AlphaFold2-assisted Domain Determination in SARS-CoV-2 Protein
Edich, M., Briggs, D., Gao, Y., Thorn, A.
10.1101/2025.01.14.632924 — Posted: 2025-01-15
Endogenous gene tagging with FnCas9 to track and sort neural lineages from 3D cortical organoids
Kumar, M., Torras, B. T., Guillemot, F., Chakraborty, D.
10.1101/2025.01.09.631995 — Posted: 2025-01-13
Timed chromatin invasion during mitosis governs prototype foamy virus integration site selection and infectivity
Lagadec, F., Singh, P. K., Calmels, C., Lapaillerie, D., Lindemann, D., Parissi, V., Cherepanov, P., Engelman, A. N., Lesbats, P.
10.1101/2025.01.10.632130 — Posted: 2025-01-11
Progressive chromosome shape changes quantified during cell divisions
Kakui, Y., Kusano, Y., Clarence, T., Lopez, M., Hirota, T., Khatri, B. S., Uhlmann, F.
10.1101/2024.11.19.623756 — Posted: 2025-01-05
Transcriptomic analysis of repeat expansion-ataxias uncovers distinct non-neuronal cell type-specific signatures of disease across the human brain
Chen, Z., Hicks, A., Brenton, J., Grant-Peters, M., Reynolds, R. H., Gustavsson, E. K., Rocca, C., Rocamora-Perez, G., Garza, R., Garcia-Ruiz, S., Dominik, N., Anderson, C., Curless, T., Montgomery, K., Macpherson, H., Nethisinghe, S., Gavriouchkina, D., Blunskyte-Hendley, M., Fairbrother-Browne, A., Lee, J., Luo, H., Efthymiou, S., Murphy, D., Hinton, F., Botia, J. A., Cortese, A., Wood, N., Giunti, P., Hardy, J., Jakobsson, J., Gandhi, S., Tucci, A., McLean, C., Jaunmuktane, Z., Houlden, H., Ryten, M.
10.1101/2025.01.03.631007 — Posted: 2025-01-03
CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy
Krentzel, D., Elphick, M., Domart, M.-C., Peddie, C. J., Laine, R. F., Shand, C., Henriques, R., Collinson, L. M., Jones, M. L.
10.1101/2023.05.11.540445 — Posted: 2024-12-26
Mechanistic studies of autophagic cargo recruitment and membrane expansion through in vitro reconstitution
Zhang, W., Litschel, T., D'Antuono, R., Davis, C., Schreiber, A., Tooze, S.
10.1101/2024.12.24.630225 — Posted: 2024-12-24
Covalent inhibitors of the RAS binding domain of PI3Ka impair tumor growth driven by RAS and HER2
Klebba, J. E., Roy, N., Bernard, S. M., Grabow, S., Hoffman, M. A., Miao, H., Tamiya, J., Wang, J., Berry, C., Esparza-Oros, A., Lin, R., Liu, Y., Pariollaud, M., Parker, H., Mochalkin, I., Rana, S., Snead, A. N., Walton, E. J., Wyrick, T. E., Aitichson, E., Bedke, K., Brannon, J. C., Chick, J. M., Hee, K., Horning, B. D., Ismail, M., Lamb, K. N., Lin, W., Metzger, J., Pastuszka, M. K., Pollock, J., Sigler, J. J., Tomaschko, M., Tran, E., Kinsella, T. M., Molina-Arcas, M., Simon, G. M., Weinstein, D. S., Downward, J., Patricelli, M. P.
10.1101/2024.12.17.629001 — Posted: 2024-12-24
Structural and functional characterization of the KHNYN extended-diKH domain for mediating ZAP antiviral activity
Youle, R. L., Lista, M. J., Bouton, C., Kunzelmann, S., Wilson, H., Cottee, M. A., Purkiss, A. G., Morris, E. R., Neil, S. J., Taylor, I. A., Swanson, C. M.
10.1101/2024.12.23.630104 — Posted: 2024-12-23

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