Channel:  Francis Crick Institute

1,325 Articles

Structural and functional basis of the non-canonical human Dicer-tRNA complex
Di Fazio, A., Hirschi, S., Battistini, F., Santos, N., Boot, J., Ajit, K., Abdullah, A., Alagia, A., Orozco, M., Gullerova, M.
10.64898/2026.08.12.744379 — Posted: 2026-08-13
MEN1 deficiency establishes a selenite-dependent binary switch in ferroptosis
Low, R. R. J., Parnandi, N., Idilli, A. I., Gjelaj, E., Subtil, F. T., Segura-Bayona, S., MacRae, J. I., Boulton, S. J.
10.64898/2026.07.16.738891 — Posted: 2026-08-12
Quantitative profiling of JMJD6-catalysed lysine hydroxylation reveals a graded, residue-dependent readout of oxygen availability
Kesavan, P., Stuermer, S. M., Räbel, K., Popp, O., Mertins, P., Cockman, M. E., Sugimoto, Y.
10.64898/2026.06.08.730680 — Posted: 2026-08-10
Cooperative and antagonistic interactions between sub-clones favour the co-existence of multiple resistance mechanisms in melanoma
Schlegelmilch, K., Hollek, V., Hooper, S., Giangreco, G., Bailey, S., Macfarlane, S., Carminati, A., Bowes, A., Strohbuecker, S., Shum, B., Turajlic, S., Fu, X., Sahai, E.
10.1101/2025.10.23.684170 — Posted: 2026-08-10
Connectomic Analysis of Mitochondria in the Central Brain of Drosophila
Longden, K. D., Rivlin, P. K., Januszewski, M., Neace, E., Scheffer, L. K., Ordish, C., Clements, J., Phillips, E., Smith, N., Takemura, S., Umayam, L., Walsh, C., Yakal, E. A., Musial, T. F., Devine, M. J., Reiser, M. B., Plaza, S. M., Berg, S.
10.1101/2024.04.21.590464 — Posted: 2026-08-07
Ancient DNA reveals matrilineal organisation and recurrent unions between dominant matrilines in Iron Age Britain
Olalde, I., Armit, I., Büster, L., Lillie, M., Urkixo F. de Zuazo, E., Ringbauer, H., Akbari, A., Castells Navarro, L., Esteve-Gomez, D., Goodchild, H., Hamilton, D., Puig i Riera, N., Sanchez-Sanz, A., Buckberry, J., Budd, C., Caffell, A., Halkon, P., Holst, M., Jerand, P., Panagiotakopulu, E., Stephens, M., Stubbings, M., Ware, P., Bleasdale, M., Booth, T., Callan, K., Caughran, E., Fischer, C.-E., Frost, T., Iliev, L., Kearns, A., Legge, M., Mah, M., Masters, M. K., Manjila, N., Nawaz, M., Oppenheimer, J., Ponce, P., Primeau, C., Silva, M., Skoglund, P., Swali, P., Qiu, L., Gregory, S., Wo
10.64898/2026.08.03.742615 — Posted: 2026-08-06
Dynamics of phosphofructokinase condensation are regulated by metabolic and redox cues
Reichert, P., Oliferenko, S., Caudron, F.
10.64898/2026.06.09.731068 — Posted: 2026-08-06
Cellular context restricts a promiscuous m6A reader IDR to a single functional effector interface for mRNA decay
Chan, W. Y., Jin, E., Cross, H., Masino, L., Ibrahim, F., Albihlal, W. S., Berger, D., Boot, J., Michrowska, A., Mouilleron, S., Skehel, M., Kranc, K. R., van Werven, F. J.
10.64898/2026.08.04.742832 — Posted: 2026-08-05
The coumarin derivative X6632 is a pan-ID protein inhibitor that suppresses tumor growth by targeting cancer cells and the tumor-associated microvasculature
Götz, L. S., Deo, A., Scherer, S. D., D'Antonio, L., Weber, H. T., Sedlmeier, G., Torre Flores, L. P., Kaiser, U., Far, E., Raviv, Z., Thiele, W., Thaler, S., Jung, N., Bräse, S., Hill, C. S., Welm, A. L., Shaked, Y., Garvalov, B. K., Sleeman, J. P.
10.64898/2026.08.05.742008 — Posted: 2026-08-05
Multi-scale modeling of human tissues from spatial transcriptomics with TERRA
Birk, S., Sanian, M. V., Vahidi, A., Ogden, S., Jafree, D. J., Miraki Feriz, A., Leonardi, C., Merchant, A., He, Z., Steele, L., Boxall, A., Sallese, M. R., Maaskola, J., Ramirez-Suastegui, C., Ogut, S., Rademaker, K., Vijayabaskar, M., Cakir, B., Marco Salas, S., Lorenzi, V., Bryant, J. M., Kyany'a, C., Jones, J. O., Rahbari, R., Raghubar, A. M., Stewart, G. D., Rumney, B., Tudor, C., Patel, M., Halliwell, J., Chan, H. M., Li, T., Stanley, H., Foster, A. R., Memi, F., Roberts, K., Trinh, A. L., Tuck, E., Gracia, T., Rai, S., Adams, D. J., Webb, S., Prete, M., Vento-Tormo, R., Nilsson, M., Lic
10.64898/2026.07.29.741565 — Posted: 2026-08-04

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