Channel:  Aligning Science Across Parkinson's (ASAP)

425 Articles

Reduced Thalamic Excitation to Motor Cortical Pyramidal Tract Neurons in a Mouse Model of Parkinsonism
Chen, L., Daniels, S., Dvorak, R., Chu, H.-y.
10.1101/2022.09.24.509340 — Posted: 2023-07-22
The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons
Russo, T., Kolisnyk, B., BS, A., Kim, T. W., Martin, J., Plessis-Belair, J., Ni, J., Pearson, J. A., Park, E. J., Sher, R. B., Studer, L., Riessland, M.
10.1101/2023.07.19.549710 — Posted: 2023-07-21
Into the deep: The subthalamic and para-subthalamic nuclei in behavioral avoidance
Serra, G. P., Guillaumin, A., Vlcek, B., Delagado-Zabalza, L., Ricci, A., Rubino, E., Dumas, S., Baufreton, J. M., Georges, F., Wallen-Mackenzie, A.
10.1101/2023.07.18.549513 — Posted: 2023-07-19
Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
Parmasad, J.-L. A., Ricke, K. M., Stykel, M. G., Buchner-Duby, B., Nguyen, B., Bruce, A., Geertsma, H. M., Lian, E., Lengacher, N. A., Callaghan, S. M., Joselin, A., Tomlinson, J. J., Schlossmacher, M. G., Stanford, W. L., Ma, J., Brundin, P., Ryan, S. D., Rousseaux, M. W. C.
10.1101/2022.05.02.490309 — Posted: 2023-07-18
Detecting Full-Length EccDNA with FLED and long-reads sequencing
Li, F., Ming, W., Lu, W., Wang, Y., Li, X., Dong, X., Bai, Y.
10.1101/2023.06.21.545840 — Posted: 2023-06-24
LRRK2 Suppresses Lysosome Degradative Activity in Macrophages and Microglia Through MiT-TFE Transcription Factor Inhibition
Yadavalli, N., Ferguson, S. M.
10.1101/2022.12.17.520834 — Posted: 2023-06-16
LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation
Fahmy, A. M., Cannon, T., Paredes, C. H., Ahmadi, A., Xu, Y. Z., Barette, B., Ibrahim, M., Lanoix, J., Arango-Duque, G., Schurr, E., Chevet, E., Thibault, P., Gruenheid, S., McBride, H., Desjardins, M.
10.1101/2023.06.14.545012 — Posted: 2023-06-16
Localization of PPM1H phosphatase tunes Parkinsons disease-linked LRRK2 kinase-mediated Rab GTPase phosphorylation and ciliogenesis
Yeshaw, W. M., Adhikari, A., Chiang, C. Y., Dhekne, H. S., Wawro, P. S., Pfeffer, S. R.
10.1101/2023.06.15.545139 — Posted: 2023-06-15
Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice.
Delignat-Lavaud, B., Kano, J., Ducrot, C., Masse, I., Mukherjee, S., Giguere, N., Moquin, L., Levesque, C., Burke, S., Bourque, M.-J., Tchung, A., Rosa-Neto, P., Levesque, D., De Beaumont, L., Trudeau, L.-E.
10.1101/2021.09.15.460511 — Posted: 2023-06-15
Interaction of an alpha-synuclein epitope with HLA-DRB1*15:01 triggers enteric features in mice reminiscent of prodromal Parkinson's disease
Garretti, F., Monahan, C., Sloan, N., Bergen, J., Shariar, S., Kim, S. W., Sette, A., Cutforth, T., Kanter, E., Sulzer, D., Agalliu, D.
10.1101/2022.02.03.479014 — Posted: 2023-06-12

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