bioRxiv directory

2 Inhibition of Soluble Epoxide Hydrolase Ameliorates Cerebral Blood Flow Autoregulation and Cognition in Alzheimer's Disease and Diabetes-Related Dementia Rat Models

Tang, C.; Border, J. J.; Zhang, H.; Gregory, A.; Bai, S.; Fang, X.; Liu, Y.; Wang, S.; Hwang, S. H.; Gao, W.; Morgan, G. C.; Smith, J.; Bunn, D.; Cantwell, C.; Wagner, K. M.; Morisseau, C.; Yang, J.; Shin, S. M.; O'Herron, P.; Bagi, Z.; Filosa, J. A.; Dong, Y.; Yu, H.; Hammock, B. D.; Roman, R. J.; Fan, F.

10.1101/2024.08.30.610540 — molecular biology — Posted on 2024-08-31

3 Chronic social defeat stress induces meningeal neutrophilia via type I interferon signaling

Kigar, S. L.; Lynall, M.-E.; DePuyt, A. E.; Atkinson, R.; Sun, V. H.; Samuels, J. D.; Eassa, N. E.; Poffenberger, C. N.; Lehmann, M. L.; Listwak, S. J.; Livak, F.; Elkahloun, A. G.; Clatworthy, M. R.; Bullmore, E. T.; Herkenham, M.

10.1101/2024.08.30.610447 — neuroscience — Posted on 2024-08-31

4 Deficiency in transmitter release triggers homeostatic transcriptional changes that increase presynaptic excitability

Cypranowska, C. A.; Bakshinska, D.; Feldthouse, M.; Choi, Y. G.; Li, R.; Newman, Z. L.; Isacoff, E. Y.

10.1101/2024.08.30.610173 — neuroscience — Posted on 2024-08-31

5 Engineering pathogen-inducible promoters for conferring disease resistance in tomato

Wei, W.; Kim, D.; Koehler, N.; Bendl, A.; Cho, M.-J.; Krasileva, K.

10.1101/2024.08.30.610566 — synthetic biology — Posted on 2024-08-31

6 Effects of lipid membranes on RNA catalytic activity and stability

Czerniak, T.; Saenz, J. P.

10.1101/2024.08.31.610601 — synthetic biology — Posted on 2024-08-31

7 LexicMap: efficient sequence alignment against millions of prokaryotic genomes

Shen, W.; Iqbal, Z.

10.1101/2024.08.30.610459 — bioinformatics — Posted on 2024-08-31

8 Directed evolution of a sequence-specific covalent protein tag for RNA labeling

Huang, R.; Ting, A. Y.

10.1101/2024.08.30.610577 — bioengineering — Posted on 2024-08-31

9 Velamins: the first green-light emitting class of wild-type Ca2+-regulated photoproteins isolated from the ctenophore Velamen parallelum

Soares, D. M.; Galeazzo, G. A.; Sgro, G. G.; Moraes, G. V.; Kronenberg, L.; Borukh, E.; Migotto, A. E.; Gruber, D. F.; Sparks, J. S.; Pieribone, V. A.; Stevani, C. V.; Oliveira, A. G.

10.1101/2024.08.30.610560 — biochemistry — Posted on 2024-08-31

10 Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production

Arafi, P.; Devkota, S.; Maesako, M.; Wolfe, M. S.

10.1101/2024.08.30.610520 — biochemistry — Posted on 2024-08-31

11 Retention of DLK1 in the endoplasmic reticulum identifies roles for EGF domain-specific O-glycans in the secretory pathway

Tashima, Y.; Tsukamoto, Y.; Tsukamoto, N.; Kondo, Y.; Uddin, E.; Furukawa, W.; Go, S.; Takeuchi, H.; Okajima, T.

10.1101/2024.08.31.610613 — biochemistry — Posted on 2024-08-31

12 Fast variance component analysis using large-scale ancestral recombination graphs

Zhu, J.; Kalantzis, G.; Pazokitoroudi, A.; Gunnarsson, A. F.; Loya, H.; Chen, H.; Sankararaman, S.; Palamara, P. F.

10.1101/2024.08.31.610262 — genetics — Posted on 2024-08-31

13 Host and antibiotic jointly select for greater virulence in Staphylococcus aureus

Su, M.; Hoang, K.; Penley, M.; Davis, M.; Gresham, J.; Morran, L.; Read, T.

10.1101/2024.08.31.610628 — evolutionary biology — Posted on 2024-08-31

14 The combined impact of climate change, pesticides and pharmaceuticals on life history and behaviour in killifish (Nothobranchius furzeri)

Kim, D.

10.1101/2024.08.15.608117 — ecology — Posted on 2024-08-31

15 Diversity and ecological roles of RNA viral communities in the cryosphere of the Tibetan Plateau

Liu, Y.; Zhang, Z.; Jiao, N.; Zhu, Y.; Zhang, R.; Dominguez-Huerta, G.; Wang, H.; Feng, M.; Wen, R.; Ji, M.; Zheng, Q.; Liu, P.; Yao, T.

10.1101/2024.08.30.610425 — ecology — Posted on 2024-08-31

16 Structural mechanism of FusB-mediated rescue from fusidic acid inhibition of protein synthesis

Gonzalez Lopez, A.; Ge, X.; Larsson, D. S. D.; Sanyal, S.; Selmer, M.

10.1101/2024.08.30.610483 — molecular biology — Posted on 2024-08-31

17 RNA Polymerase II Degradation Triggered by DNA Repair Occurs In Trans and Independently of how the Lesion is Recognised

Choudhary, R.; Munoz, J. C.; Beckerman, I.; Bastianello, G.; Bouvier, L. A.; Foiani, M.; Munoz, M. J.

10.1101/2024.08.30.610509 — molecular biology — Posted on 2024-08-31

18 Programmed ribosomal frameshifting during PLEKHM2 mRNA decoding generates a constitutively active mediator of kinesin-1-dependent lysosome transport

Khan, Y. A.; De Pace, R.; Jungreis, I.; Carancini, G.; Mudge, J. M.; Kellis, M.; Atkins, J. F.; Baranov, P.; Firth, A.; Bonifacino, J.; Loughran, G.

10.1101/2024.08.30.610563 — molecular biology — Posted on 2024-08-31

19 Dispersal of influenza virus populations within the respiratory tract shapes their evolutionary potential

Ferreri, L.; Seibert, B.; Caceres, J.; Patatanian, K.; Holmes, K. E.; Gay, C.; Faccin, F.; Cardenas Perez, M.; Carnaccini, S.; Shetty, N.; Rajao, D.; Koelle, K.; Marr, L.; Perez, D. R.; Lowen, A. C.

10.1101/2024.08.31.610648 — microbiology — Posted on 2024-08-31

20 Quantitative physiology and biomass composition of Cyberlindnera jadinii in ethanol-grown cultures

Vieira-Lara, M. A.; Warmerdam, M.; de Hulster, E. A. F.; van den Broek, M.; Daran, J.-M.; Pronk, J. T.

10.1101/2024.08.31.610600 — microbiology — Posted on 2024-08-31

21 Development of a DSM test battery to determine depression-like marmoset

Yamanaka, H.; Ishibashi, H.; Nakamura, K.

10.1101/2024.07.08.602574 — neuroscience — Posted on 2024-08-31

22 Protein-Free Catalysis of DNA Hydrolysis and Self-Integration by a Ribozyme

Mutschler, H.; Szokoli, D.

10.1101/2024.08.31.610620 — biochemistry — Posted on 2024-08-31

23 Unravelling the Maturation Pathway of a Eukaryotic Virus through Cryo-EM

Castells-Graells, R.; Hesketh, E. L.; Matsui, T.; Johnson, J. E.; Ranson, N. A.; Lawson, D. M.; Lomonossoff, G. P.

10.1101/2024.08.31.610394 — biochemistry — Posted on 2024-08-31

24 An alveolus lung-on-a-chip model of Mycobacterium fortuitum lung infection

Ektnitphong, V. A.; Dias, B. R. S.; Campos, P. C.; Shiloh, M. U.

10.1101/2024.08.30.610530 — microbiology — Posted on 2024-08-31

25 Ultrastructural and transcriptional changes during a giant virus infection of a green alga

Gajigan, A. P.; Schvarcz, C. R.; Conaco, C.; Edwards, K. F.; Steward, G. F.

10.1101/2024.08.30.610430 — microbiology — Posted on 2024-08-31

26 Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal

Gray, C. N.; Ashokkumar, M.; Janssens, D. H.; Kirchherr, J. L.; Allard, B.; Hsieh, E.; Hafer, T. L.; Archin, N. M.; Browne, E. P.; Emerman, M.

10.1101/2024.08.30.610517 — microbiology — Posted on 2024-08-31

27 Prodrug activation in malaria parasites mediated by an imported erythrocyte esterase, acylpeptide hydrolase (APEH)

Sundararaman, S. A.; Miller, J. J.; Daley, E. C.; O'Brien, K. A.; Kasak, P.; Daniels, A. M.; Edwards, R. L.; Heidel, K. M.; Bague, D. A.; Wilson, M. A.; Koelper, A. J.; Kourtoglou, E. C.; White, A. D.; August, S. A.; Apple, G. A.; Rouamba, R. W.; Durand, A. J.; Esteb, J. J.; Muller, F. L.; Johnson, R. J.; Hoops, G. C.; Dowd, C. S.; Odom John, A. R.

10.1101/2024.08.30.610542 — microbiology — Posted on 2024-08-31

28 Limosilactobacillus reuteri promotes the expression and secretion of enteroendocrine- and enterocytederived hormones

Di Rienzi, S. C.; Danhof, H. A.; Forshee, M. D.; Roberts, A.; Britton, R. A.

10.1101/2024.08.30.610555 — microbiology — Posted on 2024-08-31

29 Blanking on Blanks: Few Insect Microbiota Studies Control for Contaminants - A Systematic Review

Williamson, E.; Hammer, T.; Hogendoorn, K.; Eisenhofer, R.

10.1101/2024.08.30.610589 — microbiology — Posted on 2024-08-31

30 Decreasing ZAP Poly(ADP-ribose) Binding Enhances Antiviral Activity Against Alphaviruses

Cheng, S.-J.; Griffin, D. E.; Abraham, R.; Leung, A. K. L.

10.1101/2024.08.30.610567 — microbiology — Posted on 2024-08-31

31 Rationalizing the Effects of RNA Modifications on Protein Interactions

Vandelli, A.; Broglia, L.; Armaos, A.; Delli Ponti, R.; Tartaglia, G. G.

10.1101/2024.08.31.610603 — bioinformatics — Posted on 2024-08-31

32 Mycobacterium tuberculosis FtsB and PerM interact via a C-terminal helix in FtsB to modulate cell division

Hensel, Z.; Xu, R.; Ferreira, J. R.

10.1101/2024.03.11.584518 — molecular biology — Posted on 2024-08-31

33 Developing Biosensors for Specific Assessment of Trans-translation in Pseudomonas aeruginosa.

L'Hermitte, B.; Chauvet, T.; Georgeault Daguenet, S.; Le Yondre, N.; Jehan, P.; Gillet, R.; Baysse, C.

10.1101/2024.08.30.610505 — microbiology — Posted on 2024-08-31

34 A Novel Approach to Reducing Spinal Implant-Associated Infections

Nishizawa, M.; Hu, D.; Serhan, H.; Saleh, B.; Marcucio, R. S.; Morioka, K.

10.1101/2024.08.30.610521 — microbiology — Posted on 2024-08-31

35 Highly pathogenic avian influenza H5 virus exposure in goats and sheep

Wong, F. Y.; Yaqub, T.; Zhang, R.; Mukhtar, N.; Pervaiz, H.; Yawar, H. U. H.; Iqbal, M.; bin Aslam, H.; Aziz, M. W.; Akram, M.; Raza, S.; Low, J. G.; Cronin, P.; Laing, E. D.; Low, D. H.; Webby, R. J.; Su, Y. C.; Smith, G. J.

10.1101/2024.08.31.610397 — microbiology — Posted on 2024-08-31

36 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells

DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.

10.1101/2024.07.31.606077 — immunology — Posted on 2024-08-31

37 Foundation model of neural activity predicts response to new stimulus types and anatomy

Wang, E. Y.; Fahey, P. G.; Ding, Z.; Papadopoulos, S.; Ponder, K.; Weis, M. A.; Chang, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Schneider-Mizell, C. M.; Reid, R. C.; Collman, F.; da Costa, N. M.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.

10.1101/2023.03.21.533548 — neuroscience — Posted on 2024-08-31

38 Degeneracy in negative feedback (NFBL) and incoherent feedforward (IFFL) loops: Adaptation and resonance

Ventura, A. C.; Rotstein, H. G.

10.1101/2023.08.13.553122 — systems biology — Posted on 2024-08-31

39 Mechanosensory Systems and Sensory Integration Mediate C. elegans Negative Gravitaxis

Ackley, C. R.; Washiashi, L.; Ziaei Kajbaf, N.; Krishnamurthy, R.; Sun, Z.; Duong, V.; Choe, K.; Lane, E.; Wood, C.; Smith, E.; Pellegrini, G.; Sherwin, M.; Joshi, P.; Rothman, J. H.

10.1101/2022.03.03.482913 — neuroscience — Posted on 2024-08-31

40 Remyelination protects neurons from DLK-mediated neurodegeneration

Duncan, G. J.; Ingram, S. D.; Emberley, K.; Hill, J.; Cordano, C.; Abdelhak, A.; McCane, M.; Jenks, J. E.; Jabassini, N.; Ananth, K.; Ferrara, S. J.; Stedelin, B.; Sivyer, B.; Aicher, S. A.; Watkins, T. A.; Mishra, A.; Nelson, J.; Green, A. J.; Emery, B.

10.1101/2023.09.30.560267 — neuroscience — Posted on 2024-08-31

41 Cortical tracking of postural sways during standing balance.

Legrand, T.; Mongold, S. J.; Muller, L.; Naeije, G.; Vander Ghinst, M.; Bourguignon, M.

10.1101/2023.12.08.570752 — neuroscience — Posted on 2024-08-31

42 Local organization of spatial and shape information in the primate prefrontal cortex

Sun, Y.; Dang, W.; Jaffe, R. G.; Constantinidis, C.

10.1101/2023.08.26.554962 — neuroscience — Posted on 2024-08-31

43 Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus

McKenzie, S.; Sommer, A. L.; Donaldson, T. N.; Pimentel, I.; Kakani, M.; Choi, I. J.; Newman, E. L.; English, D. F.

10.1101/2024.07.30.605900 — neuroscience — Posted on 2024-08-31

44 Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms

Dooling, K. E.; Kim, R. T.; Kim, E. M.; Chen, E.; Abouelela, A.; Tajer, B. J.; Lopez, N. J.; Paoli, J. C.; Powell, C. J.; Luong, A. G.; Wu, S. Y. C.; Thornton, K. N.; Singer, H. D.; Savage, A. M.; Bateman, J.; DiTommaso, T.; Payzin-Dogru, D.; Whited, J. L.

10.1101/2024.08.29.610385 — physiology — Posted on 2024-08-31

45 BioLP-bench: Measuring understanding of biological lab protocols by large language models

Ivanov, I.

10.1101/2024.08.21.608694 — bioinformatics — Posted on 2024-08-31

46 Transport of herbicides by PIN-FORMED auxin transporters

Schulz, L.; Ung, K. L.; Koutnik-Abele, S.; Stokes, D. L.; Pedersen, B. P.; Hammes, U.

10.1101/2024.08.29.610046 — biochemistry — Posted on 2024-08-31

47 Evolution of sex differences in cooperation: the role of trade-offs with dispersal

Capilla-Lasheras, P.; Bircher, N.; Brown, A.; Harrison, X.; Reed, T. E.; York, J.; Cram, D.; Rutz, C.; Walker, L.; Naguib, M.; Young, A.

10.1101/2023.09.13.557370 — evolutionary biology — Posted on 2024-08-31

48 Discarded sequencing reads uncover natural variation in pest resistance in Thlaspi arvense

Galanti, D.; Jung, J. H.; Müller, C.; Bossdorf, O.

10.1101/2023.10.17.562203 — evolutionary biology — Posted on 2024-08-31

49 eIF3 engages with 3'-UTR termini of highly translated mRNAs

Mestre-Fos, S.; Ferguson, L.; Trinidad, M. I.; Ingolia, N.; Cate, J. H. D.

10.1101/2023.11.11.566681 — molecular biology — Posted on 2024-08-31

50 Bacterial defense and phage counter-defense lead to coexistence in a modeled ecosystem

Kimchi, O.; Meir, Y.; Wingreen, N. S.

10.1101/2024.07.17.603905 — microbiology — Posted on 2024-08-31

51 Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and localization

Laight, B. J.; Harper, D.; Dmytryk, N.; Zhang, S.; Garven, A.; Shi, C.; Nauman, R.; Kment, J.; Alotaibi, F.; Shapovalov, I.; Gao, Y.; Mewburn, J.; Vlasschaert, C.; LeBrun, D.; Tyryshkin, K.; Berman, D. M.; Simpson, A. L.; Graham, C.; Craig, A. W.; Basta, S.; Koti, M.; Greer, P. A.

10.1101/2024.02.27.581601 — immunology — Posted on 2024-08-31

52 Rapid synthesis and screening of natively paired antibodies against influenza hemagglutinin stem via oPool+ display

Ouyang, W. O.; Lv, H.; Liu, W.; Mou, Z.; Lei, R.; Pholcharee, T.; Wang, Y.; Dailey, K. E.; Gopal, A. B.; Choi, D.; Ardagh, M. R.; Talmage, L.; Rodriguez, L. A.; Dai, X.; Wu, N. C.

10.1101/2024.08.30.610421 — immunology — Posted on 2024-08-31

53 Computational Modeling shows Confirmation Bias during Formation and Revision of Self-Beliefs

Schröder, A.; Czekalla, N.; Mayer, A. V.; Zhang, L.; Stolz, D. S.; Korn, C. W.; Diekelmann, S.; Paulus, F. M.; Müller-Pinzler, L.; Krach, S.

10.1101/2024.08.30.610443 — neuroscience — Posted on 2024-08-31

54 Acquiring musculoskeletal skills with curriculum-based reinforcement learning

Chiappa, A. S.; Tano, P.; Patel, N.; Ingster, A.; Pouget, A.; Mathis, A.

10.1101/2024.01.24.577123 — neuroscience — Posted on 2024-08-31

55 A Transient High-dimensional Geometry Affords Stable Conjunctive Subspaces for Efficient Action Selection

Kikumoto, A.; Bhandari, A.; Shibata, K.; Badre, D.

10.1101/2023.06.09.544428 — neuroscience — Posted on 2024-08-31

56 A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection

Addante, R. J.; Clise, E.; Waechter, R.; Bengson, J.; Drane, D. L.; Perez-Caban, J.

10.1101/2024.07.15.603640 — neuroscience — Posted on 2024-08-31

57 Proactive distractor suppression in early visual cortex

Richter, D.; van Moorselaar, D.; Theeuwes, J.

10.1101/2024.04.03.587747 — neuroscience — Posted on 2024-08-31

58 Dopamine and temporal discounting: revisiting pharmacology and individual differences

Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.

10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-08-31

59 Natural genetic and transcriptomic variation in photosynthesis associated pathways contribute to adaptive traits variation in worldwide Arabidopsis thaliana population

Liu, W.; Hou, J.; Liu, L.; Lei, M.; Han, Y.; Zhu, M.; Zhang, W.; Hao, R.; Ji, Y.; Si, H.; Liu, J.; Zan, Y.

10.1101/2024.08.29.610265 — plant biology — Posted on 2024-08-31

60 Direct binding of a fungal effector by the wheat RWT4 tandem kinase activates defense

Sung, Y.-C.; Li, Y.; Bernasconi, Z.; Baik, S.; Asuke, S.; Keller, B.; Fahima, T.; Coaker, G.

10.1101/2024.04.30.591956 — plant biology — Posted on 2024-08-31

61 Exploring transient states of PAmKate to enable improved cryogenic single-molecule imaging

Perez, D.; Dowlatshahi, D. P.; Azaldegui, C. A.; Ansell, T. B.; Dahlberg, P. D.; Moerner, W. E.

10.1101/2024.04.24.590965 — biophysics — Posted on 2024-08-31

62 EuDockScore: euclidean graph neural networks for scoring protein-protein interfaces

McFee, M. C.; Kim, J.; Kim, P. M.

10.1101/2024.06.04.597410 — bioinformatics — Posted on 2024-08-31

63 StarSignDNA: Signature tracing for accurate representation of mutational processes

Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Nakken, S.; Lingjaerde, O. C.; Hovig, E.

10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-08-31

64 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.

Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; Tanmoy, A.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Loose, M.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.

10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-31

65 Hybrid Genome Sequence of Cryptococcus neoformans of Indian origin and comparative genome analysis

Sathiyamoorthy, J.; Ramakrishnan, J.

10.1101/2024.08.22.607543 — genomics — Posted on 2024-08-31

66 DNA methylation insulates genic regions from CTCF loops near nuclear speckles

Roseman, S. A.; Siegenfeld, A. P.; Lee, C.; Lue, N. Z.; Waterbury, A. L.; Liau, B. B.

10.1101/2023.07.26.550645 — genomics — Posted on 2024-08-31

67 Analysis of hepatic lentiviral vector transduction; implications for preclinical studies and clinical gene therapy protocols.

Hu, P.; Hao, Y.; Tang, W.; Diering, G. H.; Zou, F.; Kafri, T.

10.1101/2024.08.20.608805 — genetics — Posted on 2024-08-31

68 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-31

69 Experimental evolution of gene essentiality in bacteria

Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.

10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-08-31

70 Abundance and distribution of ringed and bearded seals in the Chukchi Sea: a reference for future trends

Boveng, P. L.; Chernook, V. I.; Moreland, E. E.; Conn, P. B.; Trukhanova, I. S.; Cameron, M. F.; Christman, C. L.; Crawford, J. A.; Harwood, L.; Hou, B. X.; Koslovsky, S. M.; Lindsay, J. M.; Litovka, D. I.; London, J. M.; McClintock, B. T.; Platonov, N.; Quakenbush, L.; Richmond, E. L.; Vasiliev, A.; Von Duyke, A. L.; Willoughby, A.

10.1101/2024.08.27.608330 — ecology — Posted on 2024-08-31

71 MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features

Benkeder, S.; Dinh, S.-M.; Marchal, P.; De Gea, P.; Thoby-Brisson, M.; Hubert, V.; Hristovska, I.; Pitollat, G.; Combet, K.; Cardoit, L.; Pillot, B.; Leon, C.; Wiart, M.; Marthy, S.; Honnorat, J.; Pascual, O.; Comte, J.-C.

10.1101/2024.08.29.609024 — neuroscience — Posted on 2024-08-31

72 Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution

Hills, M. H.; Ma, L.; Fang, A.; Chiremba, T.; Malloy, S.; Scott, A. R.; Perera, A. G.; Yu, R.

10.1101/2024.02.22.581574 — neuroscience — Posted on 2024-08-31

73 Dataset factors associated with age-related changes in brain structure and function in neurodevelopmental conditions

Vandewouw, M. M.; Ye, Y. J.; Crosbie, J.; Schachar, R. J.; Iaboni, A.; Georgiades, S.; Nicolson, R.; Kelley, E.; Ayub, M.; Jones, J.; Arnold, P. D.; Taylor, M. J.; Lerch, J. P.; Anagnostou, E.; Kushki, A.

10.1101/2024.05.09.591294 — neuroscience — Posted on 2024-08-31

74 Context-dependent neural preparation for information relevance vs. probability

Penalver, J. M. G.; Gonzalez-Garcia, C.; Palenciano, A. F.; Lopez-Garcia, D.; Ruz, M.

10.1101/2024.05.20.594985 — neuroscience — Posted on 2024-08-31

75 Quantifying the diverse contributions of hierarchical muscle interactions to motor function

O'Reilly, D.; Hilt, P.; de Castro Aguiar, R.; Shaw, W.; Astill, S.; Delis, I.

10.1101/2023.11.30.569159 — neuroscience — Posted on 2024-08-31

76 The development of aperiodic and periodic resting-state power between early childhood and adulthood: new insights from optically pumped magnetometers

Vandewouw, M. M.; Sato, J.; Safar, K.; Rhodes, N.; Taylor, M. J.

10.1101/2024.05.13.593983 — neuroscience — Posted on 2024-08-31

77 Learning from imagined experiences via an endogenous prediction error

Dabas, A.; Bruckner, R.; Schultz, H.; Benoit, R. G.

10.1101/2024.06.24.600192 — neuroscience — Posted on 2024-08-31

78 Green Conversations: Harnessing Plant Communication to control growth light intensity.

Stevens, J.; Davey, P.; Kasznicki, P. J.; Hofmann, T. A.; Lawson, T.

10.1101/2024.08.29.610229 — plant biology — Posted on 2024-08-31

79 Specific redox and iron homeostasis responses in the root tip of Arabidopsis upon zinc excess

Thiebaut, N.; Richtmann, L.; Sarthou, M. C. M.; Persson, D. P.; Ranjan, A.; Schloesser, M.; Boutet, S.; Rezende, L.; Clemens, S.; Verbruggen, N.; Hanikenne, M.

10.1101/2024.08.29.610234 — plant biology — Posted on 2024-08-31

80 Fc immunoreceptors promote autophagy to regulate monocyte functions

Saveanu, L.; Nugue, M.; D'Allemagne, M.; Koumantou, D.; Vetillard, M.; Cragg, M.; Bourdely, P.; Lotersztajn, S.

10.1101/2024.08.29.610296 — cell biology — Posted on 2024-08-31

81 Chromatin Remodelling in Damaged Intestinal Crypts Orchestrates Redundant TGFβ and Hippo Signalling to Drive Regeneration

Fink, M.; Njah, K.; Pagtel, S.; Cook, D.; Man, V.; Ruso, F.; Rajan, A.; Narimatsu, M.; Obersterescu, A.; Pye, M.; Trcka, D.; Chan, K.; Ayyaz, A.; Wrana, J.

10.1101/2024.08.30.610472 — molecular biology — Posted on 2024-08-30

82 Spatiotemporal Single-Cell Roadmap of Human Skin Wound Healing

Liu, Z.; Li, D.; Bian, X.; Luo, L.; Bjorklund, A.; Li, L.; Zhang, L.; Chen, Y.; Guo, L.; Gao, J.; Cao, C.; Wang, J.; He, W.; Xiao, Y.; Zhu, L.; Annusver, K.; Gopee, N. H.; Bennett, C. L.; Kasper, M.; Haniffa, M.; Sommar, P.; Xu Landen, N.

10.1101/2024.08.30.609923 — cell biology — Posted on 2024-08-30

83 Creating anatomically-derived, standardized, customizable, and three-dimensional printable head caps for functional neuroimaging

McCann, A.; Xu, E.; Yen, F.-Y.; Joseph, N.; Fang, Q.

10.1101/2024.08.30.610386 — neuroscience — Posted on 2024-08-30

84 Anatomical Abnormalities Suggest a Compensatory Role of the Cerebellum in Early Parkinson's Disease

Yun, J. J.; Gailly de Taurines, A.; Tai, Y. F.; Haar, S.

10.1101/2024.08.30.610437 — neuroscience — Posted on 2024-08-30

85 Is it me or the train moving? Humans resolve sensory conflicts with a nonlinear feedback mechanism in balance control

Asslaender, L.; Albrecht, M.; Gruber, M.; Peterka, R. J.

10.1101/2024.08.30.609158 — neuroscience — Posted on 2024-08-30

86 Novel iGluSnFR3 variants with improved kinetics and dynamic range for tracking high frequency firing at glutamatergic synapses

Tran, O.; Bertelli, S.; Hughes, H.; Lozo, L.; Plested, A.; Torok, K.

10.1101/2024.08.30.610471 — neuroscience — Posted on 2024-08-30

87 Computational screening of potential AT1R inhibitors from Nigella sativa for diabetic-hypertensive therapy

Tuli, T. R.; Mia, M.; ulla, S. N.; Gazi, M. S.; Hasan, M. N.; Biswas, P.; Tareq, M. M. I.

10.1101/2024.08.30.610463 — bioinformatics — Posted on 2024-08-30

88 Antimicrobial nanolayers of thymol and carvacrol on titanium surfaces: the crucial role of interfacial properties in thymol's superior osteogenic response

Gonzalez, A.; Minan, A. G.; Prieto, E.; Schilardi, P. L.; Fagali, N. S.; Fernandez Lorenzo de Mele, M.

10.1101/2024.08.30.610464 — bioengineering — Posted on 2024-08-30

89 High-throughput unsupervised quantification of patterns in the natural behavior of marmosets

Menegas, W.; Corbett, E.; Beliard, K.; Xu, H.; Parmar, S.; Desimone, R.; Feng, G.

10.1101/2024.08.30.610159 — animal behavior and cognition — Posted on 2024-08-30

90 Starship giant transposable elements cluster by host taxonomy using kmer-based phylogenetics

Hill, R.; Smith, D.; Canning, G.; Grey, M.; Hammond-Kosack, K.; McMullan, M.

10.1101/2024.08.30.610507 — evolutionary biology — Posted on 2024-08-30

91 Mast cells are not essential for pubertal mammary gland branching.

Kapoor, S.; Marsden, J.; Munz, C. M.; Carvalho, C.; Magalhaes Pinto, M.; Malengier-Devlies, B.; Becker, S.; Seuzaret, G.; Patatsos, K.; Akyol, R.; DALOD, M.; Pedersen, A. B.; Wilson, G. J.; Gentek, R.

10.1101/2024.08.30.610382 — developmental biology — Posted on 2024-08-30

92 The central spindle drives anaphase chromosome segregation

Chen, G.-Y.; Deng, C.; Chenoweth, D. M.; Lampson, M. A.

10.1101/2024.08.30.610502 — cell biology — Posted on 2024-08-30

93 Sympathetic Stimulation Can Compensate for Hypocalcaemia-Induced Bradycardia in Human and Rabbit Sinoatrial Node Cells

Linder, M.; Stary, T.; Bitay, G.; Nagy, N.; Loewe, A.

10.1101/2024.08.30.610432 — cell biology — Posted on 2024-08-30

94 Characterization of muscle growth and sarcomere branching in the striated musculature of C. elegans.

Fazyl, A.; Anbu, A.; Kollbaum, S.; Conklin, E.; Schroeder, N.; Vidal-Gadea, A. G.

10.1101/2024.08.30.610496 — molecular biology — Posted on 2024-08-30

95 SARS-CoV-2 Delta variant induces severe damages in the nasal cavity from the first day post-infection in the Syrian hamster model.

Fusade-Boyer, M.; Gambino, A.; Merle-Nguyen, L.; Saint-Albin, A.; Ando-Grard, O.; Boujedli, Y.; Huet, H.; Ar Gouilh, M.; Martin-Latil, S.; Klonjkowski, B.; Meunier, N.; Le Poder, S.

10.1101/2024.08.30.610497 — microbiology — Posted on 2024-08-30

96 Epigenetic control of commensal induced Th2 Responses and Intestinal immunopathology

Sangani, K. A.; Parker, M. E.; Anderson, H. D.; Chen, L.; Pandey, S. P.; Pierre, J. F.; Meisel, M.; Riesenfeld, S. J.; Hinterleitner, R.; Jabri, B.

10.1101/2024.08.30.610485 — immunology — Posted on 2024-08-30

97 Rapid synthesis and screening of natively paired antibodies against influenza hemagglutinin stem via oPool+ display

Ouyang, W. O.; Lv, H.; Liu, W.; Mou, Z.; Lei, R.; Pholcharee, T.; Wang, Y.; Dailey, K. E.; Gopal, A. B.; Choi, D.; Ardagh, M. R.; Talmage, L.; Rodriguez, L. A.; Dai, X.; Wu, N. C.

10.1101/2024.08.30.610421 — immunology — Posted on 2024-08-30

98 Computational Modeling shows Confirmation Bias during Formation and Revision of Self-Beliefs

Schroder, A.; Czekalla, N.; Mayer, A. V.; Zhang, L.; Stolz, D. S.; Korn, C. W.; Diekelmann, S.; Paulus, F. M.; Muller-Pinzler, L.; Krach, S.

10.1101/2024.08.30.610443 — neuroscience — Posted on 2024-08-30

99 Heart Rate Variability During REM Sleep is Associated with Reduced Negative Memory Bias

Morehouse, A. B.; Simon, K. C.; Chen, P.-C.; Mednick, S. C.

10.1101/2024.08.30.610388 — neuroscience — Posted on 2024-08-30

100 Human deep sleep facilitates faster cerebrospinal fluid dynamics linked to brain oscillations for sleep homeostasis and memory

Uji, M.; Li, X.; Saotome, A.; Katsumata, R.; Waggoner, R. A.; Suzuki, C.; Ueno, K.; Aritake, S.; Tamaki, M.

10.1101/2024.08.30.610454 — neuroscience — Posted on 2024-08-30

101 Predicting the irrelevant: Neural effects of distractor predictability depend on load

Lui, T. K.-Y.; Obleser, J.; Woestmann, M.

10.1101/2024.08.30.610431 — neuroscience — Posted on 2024-08-30

102 Gaze biases can reflect task-specific spatial memorization strategies

Chota, S.; Arora, K.; Kenemans, L.; Gayet, S.; Van der Stigchel, S.

10.1101/2024.08.30.610231 — neuroscience — Posted on 2024-08-30

103 Implicit Neural Representation of Multi-shell Constrained Spherical Deconvolution for Continuous Modeling of Diffusion MRI

Hendriks, T.; Vilanova, A.; Chamberland, M.

10.1101/2024.08.30.609148 — neuroscience — Posted on 2024-08-30

104 Plasma membrane H+-ATPase activation increases global transcript levels and promotes the shoot growth of light-grown Arabidopsis seedlings.

Kinoshita, S. N.; Taki, K.; Okamoto, F.; Nomoto, M. N.; Takahashi, K.; Hayashi, Y.; Ohkanda, J.; Tada, Y.; Finkemeier, I.; Kinoshita, T.

10.1101/2024.08.30.610460 — plant biology — Posted on 2024-08-30

105 Dual and spatially resolved drought responses in the Arabidopsis leaf mesophyll revealed by single-cell transcriptomics

Berrio, R. T.; Verhelst, E.; Eekhout, T.; Grones, C.; De Veylder, L.; De Rybel, B.; Dubois, M.

10.1101/2024.08.30.610433 — plant biology — Posted on 2024-08-30

106 A wheat tandem kinase sensor activates an NLR helper to trigger immunity

Chen, R.; Chen, J.; Outram, M. A.; Powell, O. R.; Arndell, T.; Gajendiran, K.; Wang, Y. L.; Ayliffe, M. A.; Blundell, C.; Figueroa, M.; Sperschneider, J.; Vanhercke, T.; Tang, D.; Xu, Y.; Zhong, G.; Gardener, C.; Yu, G.; Gourdoupis, S.; Jaremko, L.; Matny, O.; Steffenson, B. J.; Boshoff, W. H. P.; Meyer, W. B.; Arold, S. T.; Dodds, P. N.; Wulff, B. B. H.

10.1101/2024.08.30.610287 — plant biology — Posted on 2024-08-30

107 Regulatory network analysis of Dclk1 gene expression reveals a tuft cell-ILC2 axis that inhibits pancreatic tumor progression

Wang, T. C.; Laise, P.

10.1101/2024.08.30.610508 — cancer biology — Posted on 2024-08-30

108 Two-Photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure

Musimbi, Z. D.; Kundik, A.; Krucken, J.; Hauser, A. E.; Rausch, S.; Seeberger, P. H.; Niesner, R.; Leben, R.; Hartmann, S.

10.1101/2024.08.30.610452 — biophysics — Posted on 2024-08-30

109 Active foam dynamics of tissue spheroid fusion

Ongenae, S.; Svitina, H.; Belpaire, T. E. R.; Vangheel, J.; Martens, T.; Vanden Berghe, P.; Papantoniou, I.; Smeets, B.

10.1101/2024.08.30.610303 — biophysics — Posted on 2024-08-30

110 Aerosol delivery of immunotherapy and Hesperetin-loaded nanoparticles increases survival in a murine lung cancer model

Yasmin-Karim, S.; Richards, G.; Fam, A.; Ogurek, A.-M.; Sridhar, S.; Makrigiorgos, G. M.

10.1101/2024.08.30.609714 — bioengineering — Posted on 2024-08-30

111 Fluralaner treatment of chickens kills the southern house mosquito, Culex quinquefasciatus

Knape, K.; Tian, Y.; Durden, C.; Adams, D. R.; Garza, M.; Carey, J. B.; Hamer, S. A.; Hamer, G. L.

10.1101/2024.08.30.610151 — biochemistry — Posted on 2024-08-30

112 NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends

Colombo, S.; Michel, C.; Speroni, S.; Ruhnow, F.; Gili, M.; Brito, C.; Surrey, T.

10.1101/2024.08.30.610456 — biochemistry — Posted on 2024-08-30

113 Copper impedes calcification of human aortic vascular smooth muscle cells through inhibition of osteogenic transdifferentiation and promotion of extracellular matrix stability

Orlov, I.; Lenglet, G.; Avondo, C.; Beattie, J. H.; Kamel, S.; Korichneva, I.

10.1101/2024.08.30.610428 — biochemistry — Posted on 2024-08-30

114 Social complexity during early development has long-term effects on neuroplasticity in the social decision-making network

La Loggia, O.; Antunes, D. F.; Aubin-Horth, N.; Taborsky, B.

10.1101/2024.08.30.610458 — animal behavior and cognition — Posted on 2024-08-30

115 ABC-seq expands small RNAs content with randomized adapter pools operation

Yu, H.; Ye, M.; Guo, Y.; Sun, Y.; Cao, K.; Zhang, D.; Chen, F.; Zhao, Y.

10.1101/2024.08.30.610480 — genomics — Posted on 2024-08-30

116 How do self-fertilising and facultative sexual populations differ in mutation accumulation?

Kopcak, D.; Hartfield, M.

10.1101/2024.08.30.610445 — evolutionary biology — Posted on 2024-08-30

117 Trade-offs between averages and intra-individual variation within vegetative, phenological, and floral traits

Moller, C.; March-Salas, M.; Sobral, M.; Haase, J.; De Frenne, P.; Scheepens, J. F. N.

10.1101/2024.08.30.610450 — evolutionary biology — Posted on 2024-08-30

118 Coupling renewable energy infrastructure planning and biodiversity conservation: a modeling-based framework

Froidevaux, J. S. P.; LeViol, I.; Barre, K.; Bas, Y.; Kerbiriou, C.

10.1101/2024.08.30.610451 — ecology — Posted on 2024-08-30

119 Areas of high risk for mammalian biodiversity and Nature's Contributions to People under global warming

Cimatti, M.; Sacchi, A.; Di Marco, M.

10.1101/2024.08.30.610332 — ecology — Posted on 2024-08-30

120 Hungry catfish - effect of prey availability on movement dynamics of a top predator

Riha, M.; Rabaneda Bueno, R.; Vejrik, L.; Jaric, I.; Prchalova, M.; Smejkal, M.; Cech, M.; Drastik, V.; Blabolil, P.; Holubova, M.; Juza, T.; Gjelland, K.; Sajdlova, Z.; Kocvara, L.; Tuser, M.; Peterka, J.

10.1101/2024.08.30.610378 — ecology — Posted on 2024-08-30

121 β-catenin localization in the ctenophore Mnemiopsis leidyi suggests an ancestral role in cell adhesion and nuclear function

Walters, B. M.; Guttieres, L. J.; Goëb, M.; Marjenberg, S. J.; Martindale, M. Q.; Wikramanayake, A. H.

10.1101/2024.08.29.610370 — developmental biology — Posted on 2024-08-30

122 Plasma membrane transporter Progressive Ankylosis Protein Homolog (ANKH/Ankh) mediates senescence-derived extracellular citrate and is regulated by DNA damage, inflammation and ageing

James, E. N.; Teh, M.-T.; Li, Y.; Wagner-bock, C.; Al-Khateeb, Z. F.; Karen-Ng, L. P.; Roberts, T.; Synchyshyn, L.; Lewis, A.; O'Loghlen, A.; Silver, A.; Michael-Titus, A. T.; Bennett, M.; Bundy, J. G.; Mycielska, M. E.; Parkinson, E. K.

10.1101/2024.08.30.609895 — cell biology — Posted on 2024-08-30

123 LAPTM4B Alleviates Pulmonary Fibrosis by Enhancing NEDD4L-Mediated TGF-beta Signaling Suppression

Xu, K.; Pan, X.; Lian, H.; Wang, Y.; Wan, R.; Li, Z.; Pan, X.; Li, Y.; Yang, J.; Rosas, I.; Wang, L.; Yu, G.

10.1101/2024.08.30.610429 — cell biology — Posted on 2024-08-30

124 SARS-CoV-2 nsp16 is regulated by host E3 ubiquitin ligases, UBR5 and MARCHF7

Tian, L.; Liu, Z.; Gao, W.; Zhao, Z.; Li, X.; Zhang, W.; Li, Z.

10.1101/2024.08.30.610469 — microbiology — Posted on 2024-08-30

125 M. tuberculosis invades and disrupts the blood-brain barrier directly to initiate meningitis

Proust, A.; Wilkinson, K. A.; Wilkinson, R. J.

10.1101/2024.08.30.610462 — microbiology — Posted on 2024-08-30

126 Immunological memory in a teleost fish: common carp IgM+ B cells differentiate into memory and plasma cells

Chan, J. T. H.; Picard-Sanchez, A.; Dedic, N.; Majstorovic, J.; Rebl, A.; Holzer, A. S.; Korytar, T.

10.1101/2024.08.30.610468 — immunology — Posted on 2024-08-30

127 Immunophenotyping of T cells combined with Vβ antibodies identifies long lasting CMV related T cell expansions with a consistent TIGIT and PD-1 phenotype

van Ostaijen-ten Dam, M. M.; Schilham, M. W.; Lankester, A. C.; Melsen, J. E.

10.1101/2024.08.30.610465 — immunology — Posted on 2024-08-30

128 Neural contrast sensitivity is not affected by myopic blur

Domdei, N.; Mueller, J.; Renner, L.; Ameln, J.; Breher, K.; Harmening, W. M.; Wahl, S.

10.1101/2024.08.30.610275 — neuroscience — Posted on 2024-08-30

129 Distinct metabolite profiles in tissues and exudates of a monocot and dicot shaped by the environment

Siffert, A.; McLaughlin, S.; Sasse Schlaepfer, J.

10.1101/2024.08.30.610448 — plant biology — Posted on 2024-08-30

130 Simulation study of factors affecting the accuracy of transcriptome models under complex environments

Eiju, D.; Hashida, Y.; Maeda, T.; Nagano, A. J.

10.1101/2024.08.30.610453 — plant biology — Posted on 2024-08-30

131 A wheat tandem kinase and NLR pair confers resistance to multiple fungal pathogens

Lu, P.; Zhang, G.; Li, J.; Gong, Z.; Wang, G.; Dong, L.; Zhang, H.; Guo, G.; Su, M.; Wang, Y.; Zhu, K.; Wu, Q.; Chen, Y.; Li, M.; Huang, B.; Li, B.; Li, W.; Dong, L.; Hou, Y.; Cui, X.; Fu, H.; Qiu, D.; Yuan, C.; Li, H.; Zhou, J.; Han, G. z.; Chen, Y.-h.; Liu, Z.

10.1101/2024.08.30.610185 — plant biology — Posted on 2024-08-30

132 High-speed Intracellular Temperature Mapping Reveals the Existence of Non-Conductive Dissipation of Energy by Heating

Takarada, M.; Shirakashi, R.; Takinoue, M.; Ishida, M.; Morita, M.; Noji, H.; Tabata, K. V.; Funatsu, T.; Okabe, K.

10.1101/2024.08.29.610413 — biophysics — Posted on 2024-08-30

133 EXPERIMENTAL DESIGN ISSUES ASSOCIATED WITH CLASSIFICATIONS OF HYPERSPECTRAL IMAGING DATA

Nansen, C.; Mesgaran, M.; Lee, H.

10.1101/2024.08.29.610395 — bioinformatics — Posted on 2024-08-30

134 Enhancement of network architecture alignment in comparative single-cell studies

Schaechter, C.; Treppner, M.; Hackenberg, M.; Raum, H.; Boedecker, J.; Binder, H.

10.1101/2024.08.30.608255 — bioinformatics — Posted on 2024-08-30

135 Genetically-encoded phase separation sensors for intracellular probing of biomolecular condensates

Avecilla, A. R. C.; Thomas, J.; Quiroz, F. G.

10.1101/2024.08.29.610365 — bioengineering — Posted on 2024-08-30

136 Determining the off-target activity of antibiotics and novel translation initiation sites in mitochondria

Marks, J.; Young, E.; Hafner, M.

10.1101/2024.08.29.610400 — biochemistry — Posted on 2024-08-30

137 Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni

Berger, D. J.; Park, S.-K.; Crellen, T.; Vianney, T. J.; Kabatereine, N. B.; Cotton, J. A.; Sanya, R.; Elliot, A.; Tukahebwa, E. M.; Adriko, M.; Standley, C. J.; Gouvras, A.; Kinunghi, S.; Haas, H.; Rabone, M.; Emery, A.; Lamberton, P. H. L.; Webster, B. L.; Allan, F.; Buddenborg, S.; Berriman, M.; Marchant, J. S.; Doyle, S. R.; Webster, J. P.

10.1101/2024.08.29.610291 — genomics — Posted on 2024-08-30

138 Robustness Revisited: On the Neutral Evolution of Centrality and Localization

Sella, Y.; Bergman, A.

10.1101/2024.08.29.610396 — evolutionary biology — Posted on 2024-08-30

139 Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

Jaszczak, R. G.; Zussman, J. W.; Wagner, D. E.; Laird, D. J.

10.1101/2024.08.29.610420 — developmental biology — Posted on 2024-08-30

140 Analogues of the anti-malaria drug mefloquine have broad spectrum antifungal activity and are efficacious in a model of disseminated Candida auris infection.

Guin, S.; montoya, m.; wang, X.; Zarnowski, R.; Andes, D. R.; Meyers, M. J.; Williams, N.; Krysan, D. J.

10.1101/2024.08.29.610379 — microbiology — Posted on 2024-08-30

141 Effect of high-intensity anaerobic exercise on electrocortical activity in athletes and non-athletes

Costa, E. P.; Gongora, M.; Bittencourt, J.; Marinho, V.; Cagy, M.; Teixeira, S.; Nicoliche, E.; Fernandes, I.; Fagundes, D.; Machado, C.; Dias, J.; Vicente, R.; Ribeiro, P.; Gupta, D.; Velasques, B.; Budde, H.

10.1101/2024.08.29.610409 — neuroscience — Posted on 2024-08-30

142 Head And Shoulders - The Impact Of An Extended Head Model On The Simulation And Optimization Of Transcranial Electric Stimulation

Van Hoornweder, S.; Cappozzo, V.; De Herde, L.; Puonti, O.; Siebner, H.; Meesen, R.; Thielscher, A.

10.1101/2024.08.29.610251 — neuroscience — Posted on 2024-08-30

143 A microendovascular system can record precise neural signals from cortical and deep vessels with minimal invasiveness

Iwata, T.; Nakamura, H.; Uemura, T.; Araki, T.; Matsumura, T.; Abe, T.; Nezu, T.; Takagaki, M.; Ozaki, T.; Miura, S.; Fukuma, R.; John, S. E.; Grayden, D. B.; Kishima, H.; Sekitani, T.; Yanagisawa, T.

10.1101/2024.08.29.610418 — neuroscience — Posted on 2024-08-30

144 Functional characterisation of neuropeptides that act as ligands for both calcitonin-type and pigment-dispersing factor-type receptors in a deuterostome

Cong, X.; Liu, H.; Elphick, M. R.; Chen, M.

10.1101/2024.08.29.610391 — neuroscience — Posted on 2024-08-30

145 Numerosity adaptation suppresses early visual responses

Zhang, L.; Hendrikx, E.; Wang, Y.; Gayet, S.; Dumoulin, S. O.; Harvey, B. M.

10.1101/2024.08.29.610311 — neuroscience — Posted on 2024-08-30

146 Analysis and control of untemplated DNA polymerase activity for guided synthesis of kilobase-scale DNA sequences

Castle, S. D.; Woolfson, A.; Linshiz, G.; Riley, B. T.; Samuel, I. D. W.; Holliger, P.; Oldfield, L.; Hessel, A.; Gorochowski, T. E.

10.1101/2024.08.29.610422 — synthetic biology — Posted on 2024-08-30

147 Genome-wide A to G and C to T Mutations Induced by Functional TadA Variants in Escherichia coli

Wang, H.; Dong, Z.; Shi, J.; Chen, L.; Sun, T.; Zhang, W.

10.1101/2024.08.29.610230 — synthetic biology — Posted on 2024-08-30

148 A Systematic Analysis of Read-Across Adaptations in Testing Proposal Evaluations by the European Chemicals Agency

Roe, H.; Tsai, H.-H. D.; Ball, N.; Wright, F. A.; Chiu, W.; Rusyn, I.

10.1101/2024.08.29.610278 — pharmacology and toxicology — Posted on 2024-08-30

149 Spatiotemporal dynamics of tumor-CAR T-cell interaction following local administration in solid cancers

Owens, K.; Rahman, A.; Bozic, I.

10.1101/2024.08.29.610392 — cancer biology — Posted on 2024-08-30

150 Highly dynamic mechanical transitions in embryonic cell populations during Drosophila gastrulation

Gomez, J. M.; Bevilacqua, C.; Thayambath, A.; Leptin, M.; Belmonte, J.; Prevedel, R.

10.1101/2024.08.29.610383 — biophysics — Posted on 2024-08-30

151 Molecular Insights into Single Chain Lipid Modulation of Acid-Sensing Ion Channel 3

Bandarupalli, R.; Roth, R.; Klipp, R. C.; Bankston, J. R.; Li, J.

10.1101/2024.08.29.610156 — biophysics — Posted on 2024-08-30

152 Training Data Diversity Enhances the Basecalling of Novel RNA Modification-Induced Nanopore Sequencing Readouts

DING, H.; Wang, Z.; Liu, Z.; Fang, Y.; Zhang, H. H.; Sun, X.; Hao, N.; Que, J.

10.1101/2024.08.29.610342 — bioinformatics — Posted on 2024-08-30

153 Detailed delineation of the fetal brain in diffusion MRI via multi-task learning

Karimi, D.; Calixto Nunez, C.; Snoussi, H.; Cortes-Albornoz, M. C.; Velasco-Annis, C.; Rollins, C.; Jaimes, C.; Gholipour, A.; Warfield, S. K.

10.1101/2024.08.29.609697 — bioengineering — Posted on 2024-08-30

154 Isolation, identification, and characterisation of the malachite green detoxifying bacterial strain Bacillus pacificus ROC1 and the azoreductase AzrC

Bibi, S.; Breeze, C. W.; Jadoon, V.; Fareed, A.; Syed, A.; Frkic, R. L.; Zaffar, H.; Ali, M.; Zeb, I. W.; Jackson, C. J.; Naqvi, T. A.

10.1101/2024.08.29.610417 — biochemistry — Posted on 2024-08-30

155 Multiyear improvement in Batting skills following Targeted Perceptual Cognitive Training in Softball

Muraskin, J.; Sherwin, J.

10.1101/2024.08.29.610321 — animal behavior and cognition — Posted on 2024-08-30

156 qBiCo: A method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements

Karkala, F.; Simons, R. B.; Claessens, F.; Kalamara, V.; Kayser, M.; Vidaki, A.

10.1101/2024.08.29.610354 — genetics — Posted on 2024-08-30

157 Posterior specification of multi-lineage axial assembloids from human pluripotent stem cells.

Kee, N.; Leboeuf, M.; Gomez, S.; Petipre, C.; Mei, I.; Benlefki, S.; Hagey, D. W.; Dias, J.; Lallemend, F.; EL Andaloussi, S.; Ericson, J.; Hedlund, E.

10.1101/2024.08.29.610410 — cell biology — Posted on 2024-08-30

158 Roles for the canonical polarity machinery in the de novo establishment of polarity in budding yeast spores

Cooperman, B.; McMurray, M.

10.1101/2024.08.29.610423 — cell biology — Posted on 2024-08-30

159 Structural and functional insights into Cdc45 recruitment by Sld7-Sld3 for CMG complex formation

Li, H.; Ishizaki, I.; Kato, K.; Sun, X.; Muramatsu, S.; Itou, H.; Ose, T.; Araki, H.; Yao, M.

10.1101/2024.08.29.610416 — molecular biology — Posted on 2024-08-30

160 Established Pseudomonas syringae pv. tomato infection disrupts immigration of leaf surface bacteria to the apoplast

Cowles, K. N.; Iyer, A. S.; McConnell, I.; Guillemette, E. G.; Nellore, D.; Zaacks, S. C.; Barak, J. D.

10.1101/2024.08.29.610363 — microbiology — Posted on 2024-08-30

161 An Analysis of the Value-Added of Antibiogram Subgroup Stratification

Xie, C. T.; Martinez, S.; Simon, C. V.; Poutanen, S.

10.1101/2024.08.29.610362 — microbiology — Posted on 2024-08-30

162 The dual interpretation of edge time series: Time-varying connectivity versus statistical interaction

Merritt, H.; Mejia, A.; Betzel, R.

10.1101/2024.08.29.609259 — neuroscience — Posted on 2024-08-30

163 The relationship between confidence and gaze-at-nothing oculomotor dynamics during decision-making

Cos, I.; Senel, G.; Maldonado, P.; Moreno-Bote, R.

10.1101/2024.08.29.610272 — neuroscience — Posted on 2024-08-30

164 Neural representation of direct-to-reverberant energy ratio in recorded and simulated binaural room auralizations

Matten, V. G.; Stirnberg, R.; van de Par, S.; Ewert, S.; Flanagin, V. L.

10.1101/2024.08.29.610373 — neuroscience — Posted on 2024-08-30

165 Effect of sleep deprivation on fractal and oscillatory spectral measures of the sleep EEG: a window on basic regulatory processes

G. Horvath, C.; Bodizs, R.

10.1101/2024.08.29.610292 — neuroscience — Posted on 2024-08-30

166 Integrated Dual-Channel Retrograde Signaling Directs Stress Responses by Degrading the HAT1/TPL/IMPalpha-9 Suppressor Complex and Activating CAMTA3

Zeng, L.; Guo, J.; Palayam, M.; Rodriguez, C.; Gomez Mendez, M. F.; Wang, Y.; Ven, W. v. d.; Pruneda-Paz, J.; Shabek, N.; Dehesh, K.

10.1101/2024.08.29.610327 — plant biology — Posted on 2024-08-30

167 Adipose tissue protein kinase D (PKD): regulation of signalling networks and its sex-dependent effects on metabolism

Renton, M. C.; Humphrey, S. J.; Connor, T.; Martin, S. D.; Kremerer, K.; Fernando, H.; Shaw, C. S.; James, D. E.; Howlett, K. F.; McGee, S. L.

10.1101/2024.08.29.610294 — physiology — Posted on 2024-08-30

168 Role of AMPK in Atrial Metabolic Homeostasis and Substrate Preference

Toksoy, Z.; Ma, Y.; Goedeke, L.; Li, W. V.; Hu, X.; Wu, X.; Cacheux, M.; Liu, Y.; Akar, F. G.; Shulman, G. I.; Young, L. H.

10.1101/2024.08.29.608789 — physiology — Posted on 2024-08-30

169 Six months of physical inactivity is insufficient to cause chronic kidney disease in C57BL/6J mice

Opurum, P. C.; Decker, S. T.; Stuart, D.; Peterlin, A. D.; Paula, V. L.; Siripoksup, P.; Drummond, M. J.; Sanchez, A.; Ramkumar, N.; Funai, K.

10.1101/2024.08.29.610415 — physiology — Posted on 2024-08-30

170 Multi-omics analysis of virus-permissive versus hostile cellular states reveals protein networks controlling virus infection

Chen, H.; Charles, P. D.; Gu, Q.; Liberatori, S.; Robertson, D. L.; Palmarini, M.; Wilson, S. J.; Mohammed, S.; Castello, A.

10.1101/2024.08.29.610331 — pathology — Posted on 2024-08-30

171 RNA functional control by hydrolysis reversible acylation

Liu, K.; Kietrys, A. M.

10.1101/2024.08.29.610419 — cancer biology — Posted on 2024-08-30

172 Design, Synthesis, and Efficacy of Novel Trojan Horse Compounds Targeting Metabolic Vulnerabilities in Prostate Cancer

Edgerton, L. B.; Hayball, E. F.; O'Connell, F.; Ward, M. P.; O'Toole, S.; Martin, C. M.; Selemidis, S.; Brooks, R. D.; Tewari, P.; Brooks, D. A.; O'Leary, J. J.

10.1101/2024.08.29.610353 — cancer biology — Posted on 2024-08-30

173 Multimodal Spatial Proteomic Profiling in Acute Myeloid Leukemia

Ly, C.; Veletic, I.; Pacheco, C.; Dasdemir, E.; Jelloul, F. Z.; Ferri-Borgogno, S.; Basi, A. V.; Gomez, J. A.; Root, J. L.; Reville, P. K.; Sharma, P.; Basu, S.; Quesada, A. E.; Bueso-Ramos, C.; Manshouri, T.; Garcia, M. B.; Burks, J. K.; Abbas, H.

10.1101/2024.08.30.610347 — cancer biology — Posted on 2024-08-30

174 Role of Divalent Ions in Membrane Models of Polymyxin-Sensitive and Resistant Gram-Negative Bacteria

Savenko, M.; Vacha, R.; Ramseyer, C.; Rivel, T.

10.1101/2024.08.29.610330 — biophysics — Posted on 2024-08-30

175 Validation of 3D cryoEM single particle reconstruction correctness and handedness with Ewald's sphere correction

Bromberg, R.; Guo, Y.; Borek, D.; Otwinowski, Z.

10.1101/2024.08.29.610390 — biophysics — Posted on 2024-08-30

176 paraCell: A novel software tool for the interactive analysis and visualization of standard and dual host-parasite single cell RNA-Seq data

Agboraw, E.; Haese-Hill, W.; Hentzschel, F.; Briggs, E. M.; Aghabi, D.; Heawood, A.; Harding, C. R.; Schiels, B.; Crouch, K. R.; Somma, D.; Otto, T. D.

10.1101/2024.08.29.610375 — bioinformatics — Posted on 2024-08-30

177 Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells

Al-Reza, H.; Santangelo, C.; Al-Reza, A.; Iwasawa, K.; Sekiya, S.; Glaser, K.; Bondoc, A.; Merola, J.; Takebe, T.

10.1101/2024.08.30.610426 — bioengineering — Posted on 2024-08-30

178 A Comparison of Skeletal Muscle Diffusion Tensor Imaging Tractography Seeding Methods

Damon, B. M.; Guzman, R. P.; Lockard, C.; Zhou, X.

10.1101/2024.08.29.610343 — bioengineering — Posted on 2024-08-30

179 De novo design of Ras isoform selective binders

Zhang, J. Z.; Li, X.; Liu, C.; Jiang, H.; Wu, K.; Baker, D.

10.1101/2024.08.29.610300 — bioengineering — Posted on 2024-08-30

180 Systematic Optimization of Activity-Based Protein Profiling for Identification of Polysorbate-Degradative Enzymes in Biotherapeutic Drug Substance Down to 10 ppb

Tsukidate, T.; Liu, A. P.; Rivera, S.; Stiving, A. Q.; Welch, J.; Li, X.

10.1101/2024.08.29.610306 — bioengineering — Posted on 2024-08-30

181 Extracellular Vesicle-Mediated Delivery of HIF1a Reprograms Macrophages for resolutive response in Sepsis

Lee, Y.; Goo, J.; Cho, S.; Kim, S. A.; Nam, G.-H.; Kim, I.; Park, J.-W.; Jeong, C.; Kim, I.-S.

10.1101/2024.08.29.608900 — bioengineering — Posted on 2024-08-30

182 Transport of herbicides by PIN-FORMED auxin transporters

Schulz, L.; Ung, K. L.; Koutnik-Abele, S.; Stokes, D. L.; Pedersen, B. P.; Hammes, U.

10.1101/2024.08.29.610046 — biochemistry — Posted on 2024-08-30

183 Computational design of serine hydrolases

Lauko, A.; Pellock, S. J.; Anischanka, I.; Sumida, K. H.; Juergens, D.; Ahern, W.; Shida, A.; Hunt, A.; Kalvet, I.; Norn, C.; Humphreys, I. R.; Jamieson, C. S.; Kang, A.; Brackenbrough, E.; Sankaran, B.; Houk, K. N.; Baker, D.

10.1101/2024.08.29.610411 — biochemistry — Posted on 2024-08-30

184 Learning to Move and Plan like the Knight: Sequential Decision Making with a Novel Motor Mapping

Vargas, C. A. V.; Taylor, J. A.

10.1101/2024.08.29.610359 — animal behavior and cognition — Posted on 2024-08-30

185 Identification of the sex determination region and the development of a marker to distinguish males and females in megai abalone (Haliotis gigantea)

Kina, T.; Hara, M.; Hirase, S.; Kikuchi, K.

10.1101/2024.08.29.610404 — genomics — Posted on 2024-08-30

186 Atlas-scale Single-cell DNA Methylation Profiling with sciMETv3

Nichols, R. V.; Rylaarsdam, L.; O'Connell, B. L.; Shipony, Z.; Iremadze, N.; Acharya, S. N.; Adey, A.

10.1101/2024.08.29.610369 — genetics — Posted on 2024-08-30

187 Modelling the invasion, management strategies and economic impact of the invasive alien aquatic plant Egeria densa

Flores-Garcia, A.; Dobson, J. Y.; Fonfria, E. S.; Garcia-Garcia, D.; Bordehore, C.

10.1101/2024.08.29.610308 — ecology — Posted on 2024-08-30

188 Response diversity is a major driver of temporal stability in complex food webs

Danet, A.; Kefi, S.; Johnson, T. F.; Beckerman, A. P.

10.1101/2024.08.29.610288 — ecology — Posted on 2024-08-30

189 Do fungi look like macroparasites? Quantifying the patterns and mechanisms of aggregation for host-fungal parasite relationships

Schrock, S. A.; Walsman, J. C.; DeMarchi, J.; LeSage, E. H.; Ohmer, M. E. B.; Rollins-Smith, L. A.; Briggs, C. J.; Richards-Zawacki, C. L.; Woodhams, D. C.; Knapp, R. A. R.; Smith, T. C.; Haddad, C. F. B.; Becker, C. G.; Johnson, P. T. J.; Wilber, M. Q.

10.1101/2024.08.29.609018 — ecology — Posted on 2024-08-30

190 Coordinated Tbx3 / Tbx5 transcriptional control of the adult ventricular conduction system

Burnicka-Turek, O.; Trampel, K. A.; Laforest, B.; Broman, M. T.; Khan, Z.; Rytkin, E.; Li, B.; Schaffer, E.; Gadek, M.; Shen, K. M.; Efimov, I. R.; Moskowitz, I. P.

10.1101/2024.08.29.610377 — developmental biology — Posted on 2024-08-30

191 Erythropoietin-dependent Acquisition of CD71hiCD105hi Phenotype within CD235a- Early Erythroid Progenitors

Schippel, N.; Wei, J.; Ma, X.; Kala, M.; Qiu, S.; Stoilov, P.; Sharma, S.

10.1101/2024.08.29.610192 — developmental biology — Posted on 2024-08-30

192 Inferring in vivo murine cerebrospinal fluid flow using artificial intelligence velocimetry with moving boundaries and uncertainty quantification

Toscano, J. D.; Wu, C.; Ladron-de-Guevara, A.; Du, T.; Nedergaard, M.; Kelley, D. H.; Karniadakis, G. E.; Boster, K.

10.1101/2024.08.29.610340 — neuroscience — Posted on 2024-08-30

193 Longitudinal mapping of cortical change during early adolescence associated with prenatal tobacco and/or alcohol exposure in the Adolescent Brain Cognitive DevelopmentSM Study

Marshall, A. T.; Adise, S.; Kan, E.; Sowell, E. R.

10.1101/2024.08.29.610335 — neuroscience — Posted on 2024-08-30

194 Rapid visual engagement in neural processing of detailed touch interactions

Smit, S.; Ramirez-Haro, A.; Quek, G. L.; Varlet, M.; Moerel, D.; Grootswagers, T.

10.1101/2024.08.29.610402 — neuroscience — Posted on 2024-08-30

195 Distinct functional domains of Dystroglycan regulate inhibitory synapse formation and maintenance in cerebellar Purkinje cells

Jahncke, J. N.; Schnell, E.; Wright, K. M.

10.1101/2024.08.29.610348 — neuroscience — Posted on 2024-08-30

196 Epigenomic anomalies in induced pluripotent stem cells from Alzheimer disease cases

Flamier, A.; Katbe, A.; Serhani, D.; Hamam, R.; Hogan, R.; Tavares, E.; Heon, E.; Hanna, R.; Bernier, G.

10.1101/2024.08.29.610372 — neuroscience — Posted on 2024-08-30

197 Learning-Induced Effects of Practice Schedule Variability on Stimuli Discrimination Efficiency: High-Density EEG Multi-scale Analyses of Contextual Interference Effect

Cretton, A.; Schipper, K.; Hassan, M.; Ruggeri, P.; Barral, J.

10.1101/2024.08.29.610352 — neuroscience — Posted on 2024-08-30

198 The Impact of Brain-Derived Neurotrophic Factor rs6265 (Val66Met) Polymorphism on Therapeutic Electrical Stimulation for Peripheral Nerve Regeneration: A Preclinical Study of Therapy-Genotype Interactions

Walters, J. B.; Quezada, M. J.; He, S.; Steece-Collier, K.; Collier, T. J.; Sortwell, C. E.; Franz, C.

10.1101/2024.08.29.610333 — neuroscience — Posted on 2024-08-30

199 Multimodal brain imaging of insomnia, depression and anxiety symptoms: transdiagnostic commonalities and differences

de Lange, S. C.; Tissink, E.; Bresser, T.; Savage, J. E.; Posthuma, D.; van den Heuvel, M. P.; van Someren, E. J.

10.1101/2024.08.30.610439 — neuroscience — Posted on 2024-08-30

200 The Balanced Mind and its Intrinsic Neural Timescales in Advanced Meditators

Malipeddi, S.; Sasidharan, A.; Venugopal, R.; Ventura, B.; Bauer, C. C.; P.N., R.; Mehrotra, S.; John, J. P.; Kutty, B. M.; Northoff, G.

10.1101/2024.08.29.609126 — neuroscience — Posted on 2024-08-30

201 The receptor-like kinase ALE2 promotes giant cell formation in the sepal epidermis

Clark, F. K.; McGory, J.; Russell, N.; Formosa-Jordan, P.; Roeder, A. H. K.

10.1101/2024.08.29.610297 — plant biology — Posted on 2024-08-30

202 Transcription factors SlMYB41, SlMYB92 and SlWRKY71 regulate gene expression in tomato exodermis

Jo, L.; Buti, S.; Artur, M. S.; Kluck, R. M. C.; Canto Pastor, A.; Brady, S.; Kajala, K.

10.1101/2024.08.29.610307 — plant biology — Posted on 2024-08-30

203 Genomic insights into the evolution and adaptation of the memorial roses (Rosa lucieae; Rosaceae) in saline environments

Jeon, J.-H.; Shin, Y.; Kim, S.-C.

10.1101/2024.08.29.610403 — plant biology — Posted on 2024-08-30

204 Hawkmoth pheromone transduction involves G protein-dependent phospholipase Cβ signaling

Schneider, A. C.; Schroeder, K.; Chang, Y.; Nolte, A.; Gawalek, P.; Stengl, M.

10.1101/2024.08.29.610295 — physiology — Posted on 2024-08-30

205 The gut microbiota is a determinant of sexual dimorphism in ALS-linked TDP43 mice

Beraldi, E. J.; Lee, S.; Jiang, Y.; Rea, I. M.; Phull, R.; Keenan, C. M.; Stephens, M.; Bardhi, M.; Bankole, O.; Pfeffer, G.; Biernaskie, J.; McCoy, K. D.; Elinav, E.; Sharkey, K. A.; Nguyen, M. D.

10.1101/2024.08.29.610355 — physiology — Posted on 2024-08-30

206 An active model for the basilar membrane and the outer hair cells

Berger, J.; Rubinstein, J.

10.1101/2024.08.29.610286 — physiology — Posted on 2024-08-30

207 Muscle Type-Specific Modulation of Autophagy Signaling in Obesity: Effects of Caloric Restriction and Exercise

Ji, F.; Kim, J.-H.

10.1101/2024.08.29.610325 — physiology — Posted on 2024-08-30

208 Single-Molecule Studies of Cognate and Near-Cognate Elongation in an in vitro Eukaryotic Translation System

Fritsch, C.; Bhattacharya, A.; Ng, M. Y.; Li, H.; Nelson, P. C.; Cooperman, B. S.; Goldman, Y. E.

10.1101/2024.08.29.609187 — biophysics — Posted on 2024-08-30

209 Single-cell X-chromosome inactivation analysis links biased chimerism to differential gene expression and epigenetic erosion

Henning, R. H.; Rust, T. M.; Dijksterhuis, K.; Eggen, B. J. L.; Guryev, V.

10.1101/2024.08.29.610317 — bioinformatics — Posted on 2024-08-30

210 Variational inference of single cell time series

Xu, B.; Braun, R.

10.1101/2024.08.29.610389 — bioinformatics — Posted on 2024-08-30

211 Dance displays in gibbons: Biological and linguistic perspectives on structured, intentional and rhythmic body movement

Coye, C.; Caspar, K. R.; Patel-Grosz, P.

10.1101/2024.08.29.610299 — animal behavior and cognition — Posted on 2024-08-30

212 Sex and morph variation in activity from early ontogeny to maturity in ruffs (Calidris pugnax)

Rohr-Bender, V. A.; Kupan, K.; Lopez-Nava, G.; Forstmeier, W.; Hertel, A.; Razumov, V.; Martin, K.; Kempenaers, B.; Kuepper, C.

10.1101/2024.08.30.610446 — animal behavior and cognition — Posted on 2024-08-30

213 Palatability of Insecticides and Protein in Sugar Solutions to Argentine Ants

Wagner, T.; Vorjans, M.; Garsi, E.; Werneke, C.; Czaczkes, T. J.

10.1101/2024.08.29.610285 — animal behavior and cognition — Posted on 2024-08-30

214 Getting to the bottom of social learning: Chimpanzees copy arbitrary behavior from conspecifics

van Leeuwen, E. J. C.; Bryon, E.; Rogers, A.; Balaran, A.; Motsch, P.; Brooker, J. S.

10.1101/2024.08.30.607436 — animal behavior and cognition — Posted on 2024-08-30

215 Centromeric transposable elements and epigenetic status drive karyotypic variation in the eastern hoolock gibbon

Hartley, G. A.; Okhovat, M.; Hoyt, S. J.; Fuller, E.; Pauloski, N.; Alexandre, N.; Alexandrov, I. A.; Drennan, R. S.; Dubocanin, D.; Gilbert, D. M.; Mao, Y.; McCann, C.; Neph, S.; Ryabov, F.; Sasaki, T.; Storer, J. M.; Svendsen, D.; Troy, W.; Wells, J.; Core, L.; Stergachis, A.; Carbone, L.; O'Neill, R. J.

10.1101/2024.08.29.610280 — genomics — Posted on 2024-08-30

216 Reliability of canopy photography for forest ecology and biodiversity studies

von Meijenfeldt, A.; Chianucci, F.; Rigo, F.; Ottenburghs, J.; Hilpold, A.; Mina, M.

10.1101/2024.08.29.610276 — ecology — Posted on 2024-08-30

217 A-Islands: A plant dataset for biodiversity research and species monitoring on Australian islands

Schrader, J.; Coleman, D.; Abbott, I.; Bryant, S.; Buckley, R.; Crayn, D.; Gallagher, R. V.; Harris, S.; Heatwole, H.; Jackes, B.; Kreft, H.; Mills, K.; Kirkpatrick, J.; Latz, P. K.; Neldner, J.; Sattler, C.; Visoiu, M.; Wenk, E. H.; Woinarski, J. C. Z.; Wright, I. J.; Zorn, I.; Westoby, M.

10.1101/2024.08.29.609992 — ecology — Posted on 2024-08-30

218 A simple MiMIC based approach for tagging endogenous genes to visualise live transcription in vivo

Beadle, L. F.; Sutcliffe, C.; Ashe, H. L.

10.1101/2024.08.29.610339 — developmental biology — Posted on 2024-08-30

219 Phospho-regulated tuning of viscoelastic properties balances centrosome growth and strength

Amato, M.; Hwang, J. H.; Rios, M. U.; Familiari, N. E.; Rosen, M. K.; Woodruff, J. B.

10.1101/2024.08.29.610374 — cell biology — Posted on 2024-08-30

220 Patients with peripheral artery disease demonstrate altered expression of soluble and membrane-bound immune checkpoints by peripheral blood immune cells

Reitsema, R. D.; Kurt, S.; Rangel, I.; Hjelmqvist, H.; Dreifaldt, M.; Sirsjo, A.; Kumawat, A. K.

10.1101/2024.08.29.610318 — immunology — Posted on 2024-08-30

221 The lincRNA Pantr1 is a FOXG1 target gene conferring site-specific chromatin binding of FOXG1

Gather, F.; Rauleac, T.; Akol, I.; Arumugam, G.; Fullio, C. L.; Mueller, T.; Kleidonas, D.; Fischer, A.; Vlachos, A.; Backofen, R.; Vogel, T.

10.1101/2024.08.29.610239 — neuroscience — Posted on 2024-08-30

222 Stable White Matter Structure in the First Three Years after Psychosis Onset

Van Dyken, P. C.; Yang, K.; Faria, A. V.; Sawa, A.; MacKinley, M.; Khan, A. R.; Palaniyappan, L.

10.1101/2024.08.29.610312 — neuroscience — Posted on 2024-08-30

223 Integrative transcriptomics and electrophysiological profiling of hiPSC-derived neurons identifies novel druggable pathways in Koolen-de Vries Syndrome

Verboven, A. H. A.; Puvogel, S.; Kolsters, N.; Latour, B.; Linda, K.; Lewerissa, E. I.; Mijdam, R.; Dyke, E.; Duineveld, D.; Zoodsma, M.; Claassen, W. J. J.; Oudakker, A.; Schoenmaker, C.; Koolen, D. A.; de Vries, B. B. A.; 't Hoen, P.-B. A. C.; Kasri, N. N.

10.1101/2024.08.29.610281 — neuroscience — Posted on 2024-08-30

224 Emergent metabolic interactions in resistance to Clostridioides difficile invasion

Ambat, A.; van den Berg, N. I.; Zorrilla, F.; Menon, S.; Maji, A.; Basile, A.; Ghimire, S.; Kalmar, L.; Patil, K. R.; Scaria, J.

10.1101/2024.08.29.610284 — systems biology — Posted on 2024-08-30

225 Experimental Investigations of Impact Strength of Structural Wood Available in Northern Himalayas

Sheikh, U. A.; Jameel, A.; Koul, M. H.

10.1101/2024.08.29.610261 — plant biology — Posted on 2024-08-30

226 Guard-cell phytosterol homeostasis is critical for proper stomatal development

Yen, C.-C.; Hsu, Y.-W.; Leu, K.-C.; Chen, S.-S.; Chen, T.-Y.; Juan, C.-T.; Kuan, C.; Shaw, J.-F.; Ho, C.-M. K.; Jauh, G.-Y.

10.1101/2024.08.29.610202 — plant biology — Posted on 2024-08-30

227 Natural genetic and transcriptomic variation in photosynthesis associated pathways contribute to adaptive traits variation in worldwide Arabidopsis thaliana population

Zan, Y.; Liu, W.; Hou, J.; Liu, L.; Lei, M.; Han, Y.; Zhu, M.; Zhang, W.; Hao, R.; Ji, Y.; Si, H.; Liu, J.

10.1101/2024.08.29.610265 — plant biology — Posted on 2024-08-30

228 Metabolic engineering of stomatal precursor cells enhances photosynthetic water-use efficiency and vegetative growth under water-deficit conditions in Arabidopsis thaliana

Bouvier, J.; Kelly, S.

10.1101/2024.08.29.610053 — plant biology — Posted on 2024-08-30

229 A multi-omics analysis of Arabidopsis thaliana root tips under Cd exposure: A role of HY5 in limiting accumulation

Richtmann, L.; Thiebaut, N.; Ranjan, A.; Sarthou, M.; Boutet, S.; Hanikenne, M.; Clemens, S.; Verbruggen, N.

10.1101/2024.08.29.609871 — plant biology — Posted on 2024-08-30

230 NRH, a potent NAD+ booster, improves glucose homeostasis and lipid metabolism in diet-induced obese mice though an active adenosine kinase pathway.

Zeng, X.; Wang, Y.; Farias, K. G.; Rappa, A.; Darko, C.; Sauve, A. A.; Yang, Y.

10.1101/2024.08.29.610289 — pharmacology and toxicology — Posted on 2024-08-30

231 Autosomal dominant Retinitis Pigmentosa caused by the rhodopsin isoleucine 255 deletion features rapid neuroretinal degeneration, decreased synaptic connectivity, and neuroinflammation.

Cao, B.; Zhu, Y.; Gunter, A.; Kilger, E.; Bolz, S.; Hennes, C.; Muhlfriedel, R.; Paquet-Durand, F.; Arango-Gonzalez, B.; Ueffing, M.

10.1101/2024.08.29.610258 — pathology — Posted on 2024-08-30

232 Modulating Bacterial Nanocellulose Crystallinity through Post-Transcriptional Repression in Komagataeibacter xylinus

Mangayil, R.; Sarlin, E.; Ellis, T.; Santala, V.

10.1101/2024.08.29.610269 — bioengineering — Posted on 2024-08-30

233 A combination of systemic mannitol administration and mannitol-modified polyester nanoparticles facilitate gene delivery to the brain through caveolae-mediated endocytosis

Reshma, B.; Miglani, C.; Karmaka, A.; Gupta, S.; Pal, A.; Ganguli, M.

10.1101/2024.08.29.610249 — bioengineering — Posted on 2024-08-30

234 Latent learning without map-like representation of space in navigating ants

CLEMENT, L.; Schwarz, S.; Wystrach, A.

10.1101/2024.08.29.610243 — animal behavior and cognition — Posted on 2024-08-30

235 An affordable solution for investigating zebra finch intracranial electroencephalography (iEEG) signals

Abolghasemi, M.-M.; Shirsavar, S. R.; Yekani, M.

10.1101/2024.08.29.610238 — animal behavior and cognition — Posted on 2024-08-30

236 Wild jackdaws learn social tolerance to exploit new information

Arbon, J. J.; Truskanov, N.; Stott, E.; McIvor, G. E.; Thornton, A.

10.1101/2024.08.29.609864 — animal behavior and cognition — Posted on 2024-08-30

237 Bone mechano-response is driven by locomotion transitions during vertebrate evolution

Shimochi, S.; Brunet, C.; Fontcuberta-Rigo, M.; Hrovat, K.; Puigbo, P.; Nakamura, M.

10.1101/2024.08.29.610233 — evolutionary biology — Posted on 2024-08-30

238 Evaluation of a Deep Learning Based Approach to Computational Label Free Cell Viability Quantification

Reno, A. H.; Tang, J.; Sudbeck, M.; Custodio, P. F.; Baldus, B.; McLaughlin, E.; Peng, F.; Xiao, H.

10.1101/2024.08.29.610252 — cell biology — Posted on 2024-08-30

239 IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells

Camard, L.; Stephen, T.; Yahia-Cherbal, H.; Guillemot, V.; Mella, S.; Baillet, V.; Lopez-Maestre, H.; Capocefalo, D.; Cantini, L.; Leloup, C.; Marsande, J.; Sienes Bailo, J.; Dangien, A.; Pietrosemoli, N.; Hasan, M.; Wang, H.; Eckle, S. B. G.; Fourie, A. M.; Greving, C.; Shaikh, B. J.; Parker, R.; Cua, D. J.; Bianchi, E.; Rogge, L.

10.1101/2024.08.29.609178 — immunology — Posted on 2024-08-30

240 Regulatory architecture of disease resistance in maize revealed by multi-omic systems genetics

Clark, N. M.; Song, G.; Kabahuma, M. K.; Kolkman, J. M.; Christensen, S. A.; Montes-Serey, C.; Malik, S.; Nelson, R. J.; Walley, J. W.

10.1101/2024.08.29.610401 — plant biology — Posted on 2024-08-30

241 Genetic ancestry-specific meQTLs control immune function regulation in a breast cancer cohort of African and European patients

Founta, K.; Chambwe, N.

10.1101/2024.08.29.610316 — cancer biology — Posted on 2024-08-30

242 Unsupervised learning of progress coordinates during weighted ensemble simulations: Application to millisecond protein folding

Leung, J.; Frazee, N.; Brace, A.; Ramanathan, A.; Chong, L.

10.1101/2024.08.28.610178 — biophysics — Posted on 2024-08-30

243 Neural Prioritisation of Past Solutions Supports Generalisation

Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.

10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-08-30

244 Transcriptomic dynamics of petal development in the one-day flower species, Japanese morning glory (Ipomoea nil)

Nakagawa, S.; Hoshino, A.; Ito, K.; Nishide, H.; Shiratake, K.; Nagano, A. J.; Sakakibara, Y.

10.1101/2024.08.29.610218 — plant biology — Posted on 2024-08-30

245 Bisphenol A Disrupts Mitochondrial Functionality Leading to Senescence and Apoptosis in Human Amniotic Mesenchymal Stromal Cells

Ficai, S.; Papait, A.; Magatti, M.; Masserdotti, A.; Gasik, M.; Silini, A. R.; Parolini, O.

10.1101/2024.08.29.610279 — pharmacology and toxicology — Posted on 2024-08-30

246 The pro-apoptotic effect of chronic contractile activity-induced extracellular vesicles on Lewis Lung Carcinoma cells

Obi, P. O.; Souza, T. F. G.; McManus, K. J.; West, A. R.; Gordon, J. W.; Saleem, A.

10.1101/2024.08.29.610232 — cancer biology — Posted on 2024-08-30

247 Neuroendocrine differentiation (ND) in sensitivity of neuroendocrine tumor (NET) cells to ONC201/TIC10 cancer therapeutic

Ding, E.; Pinho-Schwermann, M.; Zhang, S.; Purcell, C.; El-Deiry, W. S.

10.1101/2024.08.28.610183 — cancer biology — Posted on 2024-08-30

248 Neuroendocrine Prostate Cancer Drivers SOX2 and BRN2 Confer Differential Responses to Imipridones ONC201, ONC206, and ONC212 in Prostate Cancer Cell Lines

Purcell, C.; Srinivasan, P. R.; Pinho-Schwermann, M.; MacDonald, W. J.; Ding, E.; El-Deiry, W. S. S.

10.1101/2024.08.28.610184 — cancer biology — Posted on 2024-08-30

249 Discovery of natural compounds as novel FMS-like tyrosine kinase-3 (FLT3) therapeutic inhibitors for the treatment of acute myeloid leukemia: an in silico approach

Das, U.; C, L.; Uttarkar, A.; Kumar, J.; Niranjan, V.

10.1101/2024.08.27.609927 — bioinformatics — Posted on 2024-08-30

250 In silico Exploration Natural Compounds for the Discovery of Novel DNMT3A Inhibitors as Potential Therapeutic Agents for Acute Myeloid Leukemia

Das, U.; Uttarkar, A.; Kumar, J.; Niranjan, V.

10.1101/2024.08.28.610083 — bioinformatics — Posted on 2024-08-30

251 Genome-wide methylation profiling of cell-free DNA in maternal plasma using Methylated DNA Sequencing (MeD-seq)

van Vliet, M. M.; Boers, R.; Boers, J. B.; Schaffers, O. J. M.; van der Meeren, L. E.; Steegers-Theunissen, R. P. M.; Gribnau, J.; Schoenmakers, S.

10.1101/2024.08.29.610227 — genomics — Posted on 2024-08-30

252 Developmental control of E-cadherin junctions by mechanical contractility in Drosophila embryos

Zhang, N.; Liu, W.; Lu, H.; Haering, M.; Wolf, F.; Grosshans, J.; Lv, Z.; Kong, D.

10.1101/2024.08.29.610110 — developmental biology — Posted on 2024-08-30

253 Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

Makela, J.; Papagiannakis, A.; Lin, W.-H.; Lanz, M. C.; Glenn, S.; Swaffer, M.; Marinov, G. K.; Skotheim, J. M.; Jacobs-Wagner, C.

10.1101/2024.02.26.582181 — cell biology — Posted on 2024-08-30

254 Expression of IL-1R2 by Tfr prevents their IL-1-dependent proliferation and the exacerbation of allergy

Engeroff, P.; Belbezier, A.; Vaineau, R.; Fourcade, G.; Lujan, H. D.; Bellier, B.; Graff-Dubois, S.; Klatzmann, D.

10.1101/2024.08.29.610028 — immunology — Posted on 2024-08-30

255 Maternal humoral factors modulate offspring gut immune homeostasis to mitigate diabetes development

Strachan, E.; Pessoa-Soares, L.; Ju, T.; Schcolnik-Cabrera, A.; Wang, H.; Akbari, M.; Basso, P. J.; Winer, D. A.; Huang, C.; Julien, O.; Willing, B. P.; Clemente-Casares, X.; Tsai, S.

10.1101/2024.08.28.604371 — immunology — Posted on 2024-08-30

256 Brain Charts for the Rhesus Macaque Lifespan

Alldritt, S.; Ramirez, J. S. B.; Vos de Wael, R.; Bethlehem, R.; Seidlitz, J.; Wang, Z.; Nenning, K.-H.; Esper, N. B.; Smallwood, J.; Franco, A. R.; Byeon, K.; Alexander-Bloch, A.; Messinger, A.; Chen, A.; Thiele, A.; Weiss, A. R.; Shmuel, A.; Fox, A.; Tusche, A.; Brambrink, A. M.; Falchier, A.; Hiba, B.; Jarraya, B.; Jung, B.; Butler, B.; Russ, B. E.; Howell, B. R.; Drzewiecki, C. M.; Guedj, C.; Schwiedrzik, C. M.; Amiez, C.; Wilson, C. R. E.; Klink, C.; Kroenke, C.; Constantinidis, C.; Garin, C. M.; Poirier, C.; Gale, D. J.; Leopold, D. A.; Rudko, D. A.; Amaral, D. G.; Tsao, D.; Cook, D. J.;

10.1101/2024.08.28.610193 — neuroscience — Posted on 2024-08-30

257 Targeting Norepinephrine Neurons of the Locus Coeruleus: A Comparison of Model Systems and Strategies

Wissing, C.; Eschholz, L. S.; Maheu, M.; Sauter, K.; Morellini, F.; Wiegert, J. S.; Dieter, A.

10.1101/2022.01.22.477348 — neuroscience — Posted on 2024-08-30

258 Prediction and principle discovery of drug combination based on multimodal friendship features

Chen, H.-G.; ZHOU, X.

10.1101/2024.08.28.610203 — systems biology — Posted on 2024-08-30

259 5UTR translational inhibition of neuroblastoma dependency factors using the CR-1-31-B rocaglate

Nunes, C.; Bekaert, S.-L.; Parsa, S.; Nelen, I.; Martens, F.; De Stanchina, E.; Sanders, E.; Hilgert, E.; T'sas, S.; Zhao, P.; De Vloed, F.; Eggermont, A.; Goossens, S.; Sablina, A.; Depestel, L.; Wendel, H. G.; Durinck, K.

10.1101/2024.08.29.610236 — cancer biology — Posted on 2024-08-30

260 Transglutaminase 2 function in glioblastoma tumor efferocytosis

Lui, M.; Sevinc, F.; Elgafarawi, M.; Munoz, D. G.; Keillor, J. W.; Sinclair, J.; Catana, D.; Woulfe, J.; Lorimer, I. A.

10.1101/2024.08.29.610293 — cancer biology — Posted on 2024-08-30

261 USP9X is a mechanosensitive deubiquitinase that controls tumor cell invasiveness and drug response through YAP stabilization

Biber, P.; Carminati, A.; Girard, C. A.; Mohager, W.; Ohanna, M.; Lecacheur, M.; Bouvet, O.; Audebert, S.; Khaled, M.; Tartare-Deckert, S.; Deckert, M.

10.1101/2024.08.29.610314 — cancer biology — Posted on 2024-08-30

262 TRAIL receptor agonist TLY012 in combination with PD-1 inhibition promotes tumor regression in an immune-competent mouse model of pancreatic ductal adenocarcinoma

Louie, A. D.; Huntington, K. E.; Lee, Y.; Mompoint, J.; Wu, L. J.; Lee, S.; Miner, T. J.; El-Deiry, W. S.

10.1101/2024.08.29.610345 — cancer biology — Posted on 2024-08-30

263 Mutant p53 Exploits Enhancers to Elevate Immunosuppressive Chemokine Expression and Impair Immune Checkpoint Inhibitors in Pancreatic Cancer

Mahat, D. B.; Kumra, H.; Castro, S. A.; Metcalf, E.; Nguyen, K.; Morisue, R.; Ho, W. W.; Chen, I.; Sullivan, B.; Yim, L. K.; Singh, A.; Fu, J.; Waterton, S. K.; Cheng, Y.-C.; Roberge, S.; Moiso, E.; Chauhan, V. P.; Moura Silva, H.; Spranger, S.; Jain, R. K.; Sharp, P. A.

10.1101/2024.08.28.609802 — cancer biology — Posted on 2024-08-30

264 Caveolin assemblies displace one bilayer leaflet to organize and bend membranes

Doktorova, M.; Daum, S.; Ebenhan, J.; Neudorf, S.; Han, B.; Sharma, S.; Kasson, P.; Levental, K.; Bacia, K.; Kenworthy, A. K.; Levental, I.

10.1101/2024.08.28.610209 — biophysics — Posted on 2024-08-30

265 AI-Generated Hallmarks of Aging and Cancer: A Computational Approach Using Causal Emergence and Dependency Networks

Xiong, J.

10.1101/2024.08.28.610200 — bioinformatics — Posted on 2024-08-30

266 Multi-scale reactor designs extend the physical limits of CO2 fixation

Akbari, A.; Palsson, B. O.

10.1101/2024.08.28.610213 — bioengineering — Posted on 2024-08-30

267 Label-free acoustic and optical microscopy of live tumor spheroids in hydrogel for high-throughput 3D In-vitro drug screening

Ghosh, B.; Agarwal, K.; Habib, A.; Agarwal, K.; Melandso, F.

10.1101/2024.08.28.610181 — bioengineering — Posted on 2024-08-30

268 A dual ribosomal system in the zebrafish soma and germline

Shah, A. N.; Leesch, F.; Lorenzo-Orts, L.; Grundmann, L.; Novatchkova, M.; Haselbach, D.; Calo, E.; Pauli, A.

10.1101/2024.08.29.610041 — developmental biology — Posted on 2024-08-30

269 Phase separation promotes Atg8 lipidation for autophagy progression

Fujioka, Y.; Tsuji, T.; Kotani, T.; Kumeta, H.; Kakuta, C.; Fujimoto, T.; Nakatogawa, H.; Noda, N. N.

10.1101/2024.08.29.610189 — cell biology — Posted on 2024-08-30

270 Single-nucleosome imaging reveals principles of transient multiscale chromatin unfolding triggered by histone ADP-ribosylation at DNA lesions

GARCIA FERNANDEZ, F.; Chapuis, C.; PARK, J.; Pinto Jurado, E.; Imburchia, V.; Longarini, E. J.; Taddei, A.; Sokolovska, N.; Matic, I.; Huet, S.; Mine Hattab, J.

10.1101/2024.08.28.610034 — cell biology — Posted on 2024-08-30

271 Imaging the interactions of chimeric antigen receptor-expressing T-cells with colorectal cancer cells

Banik, D.; Ward, C.; Zhang, Z.; Heraghty, D.; Suresh, P.; Li, B.; Kedia, S.; Davis, S.; Roy, J.; Chapman, M.; Mahata, B.; Klenerman, D.

10.1101/2024.08.29.610222 — immunology — Posted on 2024-08-30

272 Invariant Natural Killer T cells control positively and negatively the development of hepatocellular carcinoma

Papanastasatou, M.; Gioulbasani, M.; Nakou, E.; Galaras, A.; Rubio-Tomas, T.; Talianidis, I.; Eliopoulos, A.; Hatzis, P.; Verykokakis, M.

10.1101/2024.08.29.610221 — immunology — Posted on 2024-08-30

273 Dietary zinc restriction mimics protein restriction and extends lifespan in Drosophila

Kosakamoto, H.; Aikawa, H.; Kitazawa, S.; Sakuma, C.; Okada, R.; Miura, M.; Obata, F.

10.1101/2024.08.28.610190 — physiology — Posted on 2024-08-30

274 Impaired S-nitrosylation of Cx43 prevents arrhythmogenicity and myocardial injury upon cardiac stress in Duchenne Muscular Dystrophy

Munoz, M. F.; Quan, J. J.; Nguyen, T. T.; Nuno, J.; Sheehy, A.; Burboa, P. C.; Gaete, P. S.; Lillo, M. A.; Contreras, J. E.

10.1101/2024.08.29.610357 — physiology — Posted on 2024-08-30

275 The amyloid oligomer modulator anle138b has disease modifying effects in a human IAPP transgenic mouse model of type 2 diabetes mellitus (hIAPP Ob/Ob mice)

Hoppener, J.; Griesinger, C.; Alabariqi, M. M. H.; Vassallo, N.; Eijkelkamp, N.; Giese, A.; Baauw, S. M. G.; Fens, S.; Ryazanov, S.; Leonov, A.; Willemen, H. L. D. M.; Gerritsen, B.; Stathonikos, N.; Khemtemourian, L.; Seychell, R. M.; El Saghir, A.; Versteeg, S.

10.1101/2024.08.27.609850 — pathology — Posted on 2024-08-30

276 Integer topological defects provide a new way to quantify and classify cell sheets

Zhao, Z.; Li, H.; Yao, Y.; Zhao, Y.; Serra, F.; Kawaguchi, K.; Zhang, H.; Chate, H.; Sano, M.

10.1101/2024.08.28.610106 — biophysics — Posted on 2024-08-30

277 Systematic evaluation of de novo mutation calling tools using whole genome sequencing data

Shah, A.; Monger, S.; Troup, M.; Ip, E. K.; Giannoulatou, E.

10.1101/2024.08.28.610208 — bioinformatics — Posted on 2024-08-30

278 Exploiting XAI maps to improve MS lesion segmentation and detection in MRI

Spagnolo, F.; Molchanova, N.; Ocampo Pineda, M.; Melie-Garcia, L.; Bach Cuadra, M.; Granziera, C.; Andrearczyk, V.; Depeursinge, A.

10.1101/2024.08.29.610090 — bioengineering — Posted on 2024-08-30

279 Isotope analysis of bird eye lens provides early-life information

Hasegawa, E. A.; Matsubayashi, J.; Tayasu, I.; Goto, T.; Inoue, H.; Rossberg, A. G.; Yoshimizu, C.; Hasegawa, M.; Akasaka, T.

10.1101/2024.08.28.610164 — ecology — Posted on 2024-08-30

280 3D-Aligner: An advanced computational tool designed to correct image distortion in expansion microscopy for precise 3D reconstitution and quantitative analysis

Loi, J.; Ghone, D.; Qu, X.; Suzuki, A.

10.1101/2024.08.28.610199 — cell biology — Posted on 2024-08-30

281 ChimpanSEE, ChimpanDO: Grooming and play contagion in chimpanzees

Sandars, G.; Brooker, J. S.; Clay, Z.

10.1101/2024.08.29.610309 — animal behavior and cognition — Posted on 2024-08-30

282 Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size.

Fromm, B.; Sorger, T.

10.1101/2024.05.21.595052 — evolutionary biology — Posted on 2024-08-30

283 CRISPR/dCas-mediated counter-silencing: Reprogramming dCas proteins into antagonists of xenogeneic silencers

Wiechert, J.; Badia Roige, B.; Dohmen-Olma, D.; Hindra, H.; Zhang, X.; Elliot, M.; Frunzke, J.

10.1101/2024.08.29.610263 — microbiology — Posted on 2024-08-30

284 Global brain asymmetry and its variations in aging and related diseases

Hu, H.; Pu, Y.; Abuduaini, Y.; Wang, X.; Francks, C.; Thompson, P. M.; Kong, X.-Z.

10.1101/2024.08.29.610247 — neuroscience — Posted on 2024-08-30

285 Reduced neural distinctiveness of speech representations in the middle-aged brain

Guo, Z.-c.; McHaney, J. R.; Parthasarathy, A.; Chandrasekaran, B.

10.1101/2024.08.28.609778 — neuroscience — Posted on 2024-08-30

286 Estrus-Tracking Cortical Neurons Integrate Social cues and Reproductive states to Adaptively Control Sexually Dimorphic Sociosexual Behaviors

Wang, Y.; Song, X.; Chen, X.; Zhou, Y.; Ma, J.; Zhang, F.; Wei, L.; Qi, G.; Yadav, N.; Miao, B.; Yan, Y.; Yuan, G.; Mi, D.; Rajasethupathy, P.; Ibanez-Tallon, I.; Jia, X.; Heintz, N.; Li, K.

10.1101/2024.08.30.610466 — neuroscience — Posted on 2024-08-30

287 GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine

Yamamoto, T.; Ueji, K.; Mizuta, H.; Inui-Yamamoto, C.; Kumamoto, N.; Shibata, Y.; Ugawa, S.

10.1101/2024.08.30.610470 — neuroscience — Posted on 2024-08-30

288 Movement-related activity in the internal globus pallidus of the parkinsonian macaque

Kase, D.; Zimnik, A. J.; Han, Y.; Harsch, D. R.; Bacha, S.; Cox, K. M.; Bostan, A. C.; Richardson, R. M.; Turner, R. S.

10.1101/2024.08.29.610310 — neuroscience — Posted on 2024-08-30

289 Developmental transformations of Purkinje cells tracked by DNA electrokinetic mobility

Brandenburg, C.; Crutcher, G. W.; Romanowski, A. J.; Donofrio, S. G.; Duraine, L. R.; Owusu-Mensah, R. N. A.; Sugihara, I.; Blatt, G. J.; Sillitoe, R. V.; Poulopoulos, A.

10.1101/2024.08.29.610366 — neuroscience — Posted on 2024-08-30

290 Otoacoustic emissions predict cochlear-nerve but not behavioral frequency tuning in an avian vocal-communication specialist

Karosas, D. M.; Gonzales, L.; Wang, Y.; Bergevin, C.; Carney, L. H.; Henry, K. S.

10.1101/2024.08.29.610326 — neuroscience — Posted on 2024-08-30

291 Transformations in prefrontal ensemble activity underlying rapid threat avoidance learning

Gabriel, C. J.; Gupta, T. A.; Sanchez-Fuentes, A.; Zeidler, Z. E.; Wilke, S. A.; DeNardo, L. A.

10.1101/2024.08.28.610165 — neuroscience — Posted on 2024-08-30

292 Defensive freezing sharpens threat-reward information processing during approach-avoidance decision making

Klaassen, F. H.; Bramson, B.; Schoffelen, J.-M.; de Voogd, L. D.; Roelofs, K.

10.1101/2024.08.29.610250 — neuroscience — Posted on 2024-08-30

293 Liprin-α/RIM complex regulates the dynamic assembly of presynaptic active zones via liquid-liquid phase separation

Jin, G.; Campos, J.; Liu, Y.; de la Cruz, B. M.; Zhang, S.; Liang, M.; Li, K.; Xie, X.; Yu, C.; Sterky, F.; Acuna, C.; Wei, Z.

10.1101/2024.08.29.610253 — neuroscience — Posted on 2024-08-30

294 Transitions from monotonic to tuned responses in recurrent neural network models during timing prediction

Hendrikx, E.; Manns, D.; van der Stoep, N.; Testolin, A.; Zorzi, M.; Harvey, B. M.

10.1101/2024.08.29.610320 — neuroscience — Posted on 2024-08-30

295 Plasmodesmal closure elicits stress responses

Tee, E.; Breakspear, A.; Papp, D.; Thomas, H. R.; Walker, C.; Bellandi, A.; Faulkner, C.

10.1101/2024.05.08.593115 — plant biology — Posted on 2024-08-30

296 Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state.

Lluis, F.; Ellaithy, Y.; Abreu de Oliveira, W. A.; Pabba, A.; Qualizza, A.; Richard, F.; Athanasouli, P.; Luci, C. R.; De Wispelaere, W.; Mourao, L.; Hamer, S.; Moens, S.; De Jaime-Soguero, A.; Francesca Baietti, M.; Hutten, S. J.; Jonkers, J.; Sammut, S.-J.; Soenen, S. J.; Scheele, C. L.; Bruna, A.; Desmedt, C.; Annibali, D.

10.1101/2024.03.08.584051 — cancer biology — Posted on 2024-08-30

297 Structural basis of interdomain communication in PPARγ

Mosure, S. A.; Munoz-Tello, P.; Kuo, K.-T.; MacTavish, B.; Yu, X.; Scholl, D.; Williams, C. C.; Strutzenberg, T. S.; Li, J.; Bass, J.; Brust, R.; Kalkhoven, E.; Deniz, A. A.; Griffin, P. R.; Kojetin, D.

10.1101/2022.07.13.499031 — biophysics — Posted on 2024-08-30

298 Emergent collective alignment gives competitive advantage to longer cells during range expansion

van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.

10.1101/2024.01.26.577059 — biophysics — Posted on 2024-08-30

299 GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator

Fahrenberger, M.; Esk, C.; von Haeseler, A.

10.1101/2024.07.02.601501 — bioinformatics — Posted on 2024-08-30

300 Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways

Askarova, A.; Yaa, R. M.; Marzi, S. J.; Nott, A.

10.1101/2024.08.29.610255 — genomics — Posted on 2024-08-30

301 Extensive population structure highlights an apparent paradox of stasis in the impala (Aepyceros melampus)

Garcia-Erill, G.; Wang, X.; Rasmussen, M. S.; Quinn, L.; Khan, A.; Bertola, L. D.; Santander, C. G.; Balboa, R. F.; Ogutu, J. O.; Pecnerova, P.; Hanghoej, K.; Kuja, J.; Nursyifa, C.; Masembe, C.; Muwanika, V.; Bibi, F.; Moltke, I.; Siegismund, H. R.; Albrechtsen, A.; Heller, R.

10.1101/2024.04.19.590257 — evolutionary biology — Posted on 2024-08-30

302 Loss of ErbB3 redirects Integrin β1 from early endosomal recycling to secretionin extracellular vesicles

Rodrigues-Junior, D. M.; Saez-Ibanez, A. R.; Terabayashi, T.; Daubel, N.; Makinen, T.; Idevall-Hagren, O.; Ferby, I.; Moustakas, A.; Ferby, I.

10.1101/575449 — cell biology — Posted on 2024-08-30

303 The transcription factor Sfp1 imprints specific classes of mRNAs and links their synthesis to cytoplasmic decay

Kelbert,, M.; Jordan-Pla, A.; de-Miguel-Jimenez, L.; Garcia-Martinez, J.; Selitrennik, M.; Guterman,, A.; Henig,, N.; Granneman,, S.; Perez-Ortin, J. E.; Chavez, S.; Choder, M.

10.1101/2023.09.13.557510 — molecular biology — Posted on 2024-08-30

304 RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion

Haase, R.; Ren, B.; Dos Santos Pacheco, N.; Visentin, R.; Maco, B.; Mondragon Flores, R.; Vadas, O.; Soldati-Favre, D.

10.1101/2024.08.29.610260 — microbiology — Posted on 2024-08-30

305 Rapid resistance evolution against phage cocktails

van der Steen, B. A.; Gralka, M.; Mulla, Y.

10.1101/2024.08.27.609872 — microbiology — Posted on 2024-08-30

306 DNA damage drives antigen diversification through mosaic VSG formation in Trypanosoma brucei

Smith, J. E.; Wang, K. J.; Kennedy, E. M.; Hakim, J. M.; So, J.; Beaver, A. K.; Magesh, A.; Gilligan-Steinberg, S. D.; Zheng, J.; Zhang, B.; Moorthy, D. N.; Akin, E. H.; Mwakibete, L.; Mugnier, M. R.

10.1101/2024.03.22.582209 — microbiology — Posted on 2024-08-30

307 Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis

Gruschow, S.; Steketee, P. C.; Matthews, K. R.; Morrison, L. J.; White, M. F.; Grey, F.

10.1101/2024.08.29.610254 — microbiology — Posted on 2024-08-30

308 Spatial predictive context speeds up visual search by biasing local attentional competition

Bouwkamp, F. G.; de Lange, F.; Spaak, E.

10.1101/2023.07.14.548976 — neuroscience — Posted on 2024-08-30

309 Functional MRI reveals that subcortical auditory push-pull interactions rely on intercollicular integrity

Severo, F.; Valente, M.; Shemesh, N.

10.1101/2024.05.21.594962 — neuroscience — Posted on 2024-08-30

310 A deep-learning based analysis framework for ultra-high throughput screening time-series data

Balzerowski, P.; Hebing, L.; Lima, F. d. A. e.; Manesso, E.; Mueller, T.; Diedam, H.; Gnutt, D.

10.1101/2024.08.22.609110 — bioinformatics — Posted on 2024-08-30

311 Research disturbance negatively impacts incubation behaviour of female Great Tits

Clemencin, L.; Barba, E.; Diez-Mendez, D.

10.1101/2024.03.28.587136 — animal behavior and cognition — Posted on 2024-08-30

312 Less, but more: new insights from appendicularians on chordate Fgf evolution and the divergence of tunicate lifestyles.

Sanchez-Serna, G.; Badia-Ramentol, J.; Bujosa, P.; Ferrandez-Roldan, A.; Torres-Aguila, N.; Fabrega-Torrus, M.; Wibisana, J. N.; Mansfield, M. J.; Plessy, C.; Luscombe, N. M.; Albalat, R.; Canestro, C.

10.1101/2024.08.30.610304 — evolutionary biology — Posted on 2024-08-30

313 Impact of Run-of-River Damming on Increasing Phytoplankton Biomass and Species Shift in a Large Amazonian River

Pineda, A.; Campos, B. M.; Zanon, F. M.; Felicio, R. S.; Rodrigues, L. C.

10.1101/2024.06.22.600178 — ecology — Posted on 2024-08-30

314 Local weakening of cell-ECM adhesion triggers basal tissue folding via changes in cell shape, actomyosin organization and E-cad levels

Valencia-Exposito, A.; Khalilgharibi, N.; Mao, Y.; Martin-Bermudo, M. D.

10.1101/2024.08.27.609853 — developmental biology — Posted on 2024-08-30

315 Deciphering the coupling state-dependent transcription termination in the Escherichia coli galactose operon

N, M. P. A.; Wang, X.; Jeon, H. J.; Lim, H. M.

10.1101/2024.08.28.610070 — molecular biology — Posted on 2024-08-30

316 Potential probiotic aquaculture microbiomes: detecting inhibition of the fish pathogen Vibrio anguillarum by a complex algal community

Smahajcsik, D.; Roager, L.; Strube, M. L.; Zhang, S.; Gram, L.

10.1101/2024.08.27.609935 — microbiology — Posted on 2024-08-30

317 SLC35A2 modulates paramyxovirus fusion events during infection

Yang, Y.; Wang, Y.; Campbell, D.; Lee, H.-W.; Wang, L.; Baldridge, M.; Lopez, C. B.

10.1101/2024.08.27.609835 — microbiology — Posted on 2024-08-30

318 TGF-β signaling promotes the expression of proviral circular RNA ciTRAN in HIV-1 infection

Choudhary, A.; Malick, K.; Dalavi, R.; Chande, A.

10.1101/2024.08.28.610092 — microbiology — Posted on 2024-08-30

319 Hypothalamic control of noradrenergic neurons stabilizes sleep

Broglia, G.; Corsi, G.; Prouvot Bouvier, P.-H.; Vassalli, A.; Tafti, M.; Bandarabadi, M.

10.1101/2023.10.22.563502 — neuroscience — Posted on 2024-08-30

320 Parallel Networks to simulate complex multicellular dynamics - A proof of concept with intervertebral disc cell systems

Baumgartner, L.; Gonzalez Ballester, M. A.; Noailly, J.

10.1101/2022.08.08.503195 — systems biology — Posted on 2024-08-30

321 Plant-plant interactions in wheat mixtures modulate mean and variance of susceptibility to Septoria tritici blotch

Mathieu, L.; Ducasse, A.; Ballini, E.; Morel, J.-B.

10.1101/2024.08.26.609704 — plant biology — Posted on 2024-08-30

322 Conjugation of dn-OPDA with amino acids inhibits its hormonal bioactivity in Marchantia polymorpha

Liang, W.; Zamarreno, A. M.; Torres-Montilla, S.; de la Torre, A.; Totozafy, J. C.; Kaji, T.; Ueda, M.; Corso, M.; Garcia-Mina, J. M.; Solano, R.; Chini, A.

10.1101/2024.08.27.609933 — plant biology — Posted on 2024-08-30

323 Immune aging impairs muscle regeneration via macrophage-derived anti-oxidant selenoprotein P

Hoang, D.-H.; Bouviere, J.; Galvis, J.; Moulle, P.; Migliavacca, E.; Juban, G.; Liot, S.; Stuelsatz, P.; Le Grand, F.; Feige, J. N.; Mounier, R.; Chazaud, B.

10.1101/2024.08.28.610036 — physiology — Posted on 2024-08-30

324 Amputation Triggers Long-Range Epidermal Permeability Changes in Evolutionarily Distant Regenerative Organisms

10.1101/2024.08.29.610385 — physiology — Posted on 2024-08-30

325 Differential regulation of eye specification in Drosophila by Polycomb Group (PcG) epigenetic repressors

Brown, H. E.; Weasner, B. P.; Kumar, J. P.

10.1101/2024.08.28.610158 — developmental biology — Posted on 2024-08-30

326 Urban Cepaea nemoralis snails are less likely to have nematodes trapped within their shells

Dahirel, M.; Reyne, H.; De Wolf, K.; Bonte, D.

10.1101/2024.03.07.583959 — ecology — Posted on 2024-08-30

327 Translation elongation as a rate limiting step of protein production

Lyons, E. F.; Devanneaux, L. C.; Muller, R. Y.; Freitas, A. V.; Meacham, Z. A.; McSharry, M. V.; Trinh, V. N.; Rogers, A. J.; Ingolia, N. T.; Lareau, L. F.

10.1101/2023.11.27.568910 — molecular biology — Posted on 2024-08-30

328 A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection

Addante, R. J.; Clise, E.; Waechter, R.; Bengson, J.; Drane, D. L.; Perez-Caban, J.

10.1101/2024.07.15.603640 — neuroscience — Posted on 2024-08-30

329 The Recurrent Temporal Restricted Boltzmann Machine Captures Neural Assembly Dynamics in Whole-brain Activity

Quiroz Monnens, S.; Peters, C.; Hesselink, L. W.; Smeets, K.; Englitz, B.

10.1101/2024.02.02.578570 — neuroscience — Posted on 2024-08-30

330 Individualized Cerebellar Damage Predicts the Behavioral Disorders in Children with Brainstem Tumors

Jia, H.; Wang, K.; Zhang, M.; Gu, G.; Mai, Y.; Wu, X.; Chu, C.; Yin, X.; Zhang, P.; Fan, L.; Zhang, L.

10.1101/2024.08.01.606261 — neuroscience — Posted on 2024-08-30

331 Nuclear assembly in giant unilamellar vesicles encapsulating Xenopus egg extract

Takamori, S.; Mimura, H.; Osaki, T.; Kondo, T.; Shintomi, M.; Shintomi, K.; Ohsugi, M.; Takeuchi, S.

10.1101/2024.06.25.600006 — synthetic biology — Posted on 2024-08-30

332 Phase behaviour of hnRNPA1 low-complexity domain mutants described by different sequence-dependent models

Feito, A.; Sanchez-Burgos, I.; Tejero, I.; Sanz, E.; Rey, A.; Collepardo-Guevara, R.; Tejedor, A. R.; Espinosa, J. R.

10.1101/2024.08.28.610132 — biophysics — Posted on 2024-08-30

333 Accurate Bayesian phylogenetic point estimation using a tree distribution parameterized by clade probabilities

Berling, L.; Klawitter, J.; Bouckaert, R.; Xie, D.; Gavryushkin, A.; Drummond, A.

10.1101/2024.02.20.581316 — bioinformatics — Posted on 2024-08-30

334 An automated convergence diagnostic for phylogenetic MCMC analyses

Berling, L.; Bouckaert, R.; Gavryushkin, A.

10.1101/2023.08.10.552869 — bioinformatics — Posted on 2024-08-30

335 An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

Wu, J.; Xi, J.; Zhu, Z.; Peng, Q.; Liu, C.; Cao, Y.; Luan, Y.; Wan, Z.

10.1101/2024.08.27.610021 — bioengineering — Posted on 2024-08-30

336 Peaks and Distributions of White Matter Tract-related Strains in Bicycle Helmeted Impacts: Implication for Helmet Ranking and Optimization

Zhou, Z.; Fahlstedt, M.; Li, X.; Kleiven, S.

10.1101/2024.04.26.591318 — bioengineering — Posted on 2024-08-30

337 Modeling of vascular interactions in endochondral ossification using human embryonic stem cells-derived organoid on a microfluidic chip

Kesharwani, A.; Tani, S.; Nishikawa, M.; Sakai, Y.; Okada, H.; Ohba, S.; Chung, U.-i.; Hojo, H.

10.1101/2024.08.18.608259 — bioengineering — Posted on 2024-08-30

338 JNK signaling-mediated exocytosis coordinates epithelial cell-turnover in Drosophila ribosomal protein mutants

Akai, N.; Igaki, T.; Ohsawa, S.

10.1101/2023.12.27.573431 — developmental biology — Posted on 2024-08-30

339 Temperature and host plant ecotype drive nitrogen fixation, but not nodule community composition, in hairy

Fudge, R.; Gardner, P.; Denison, R. F.; Burghardt, L.; Grossman, J.

10.1101/2024.08.28.610160 — plant biology — Posted on 2024-08-29

340 CYP76BK1 orthologs catalyze furan and lactone ring formation in clerodane diterpenoids across the mint family

Schlecht, N. J.; Lanier, E.; Andersen, T.; Brose, J.; Holmes, D.; Hamberger, B.

10.1101/2024.08.28.609960 — plant biology — Posted on 2024-08-29

341 Metagenomic analyses of the plastisphere reveals a common functional potential across oceans

Lips, S.; Schmitt-Jansen, M.; Borchert, E.

10.1101/2024.08.29.610283 — microbiology — Posted on 2024-08-29

342 The archaeal family 3 polyphosphate kinase reveals a function of polyphosphate as energy buffer under low energy charge

Hoefmann, S.; Schmerling, C.; Stracke, C.; Niemeyer, F.; Schaller, T.; Snoep, J. L.; Braesen, C.; Siebers, B.

10.1101/2024.08.28.610084 — microbiology — Posted on 2024-08-29

343 The SP140-RESIST pathway regulates interferon mRNA stability and antiviral immunity

Witt, K. C.; Dziulko, A.; An, J.; Lee, O. V.; Liu, G.; Lari, A. C.; Chavez, R.; Turner, D. J.; Cheng, A.; Kotov, D. I.; Abraham, P.; Lee, A. Y.; Dhaliwal, H.; Coscoy, L.; Glaunsinger, B.; Chuong, E.; Vance, R.

10.1101/2024.08.28.610186 — immunology — Posted on 2024-08-29

344 Does slow oscillation-spindle coupling contribute to sleep-dependent memory consolidation? A Bayesian meta-analysis

Ng, T.; Noh, E.; Spencer, R. M. C.

10.1101/2024.08.28.610060 — neuroscience — Posted on 2024-08-29

345 Design of diverse, functional mitochondrial targeting sequences across eukaryotic organisms using variational autoencoder

Boob, A. G.; Tan, S.-I.; Zaidi, A.; Singh, N.; Xue, X.; Zhou, S.; Martin, T. A.; Chen, L.-Q.; Zhao, H.

10.1101/2024.08.28.610205 — synthetic biology — Posted on 2024-08-29

346 Genomically recoded Escherichia coli with optimized functional phenotypes

Isaacs, F.; Hemez, C.; Mohler, K.; Radford, F.; Moen, J.; Rinehart, J.

10.1101/2024.08.29.610322 — synthetic biology — Posted on 2024-08-29

347 Development of ketobenzothiazole-based peptidomimetic TMPRSS13 inhibitors with low nanomolar potency

Joushomme, A.; Desilets, A.; Champagne, W.; Hassanzadeh, M.; Lemieux, G.; Gravel-Trudeau, A.; Lepage, M.; Lafreniere, S.; Froehlich, U.; List, K.; Boudreault, P.-L.; Leduc, R.

10.1101/2024.08.28.609965 — pharmacology and toxicology — Posted on 2024-08-29

348 Orchestrating Improbable Chemistries: Structural Snapshots of B12-Dependent Methionine Synthase's Catalytic Choreography

Mendoza, J.; Yamada, K.; Castillo, C.; Wilhelm, C. A.; Koutmos, M.

10.1101/2024.08.29.610163 — biochemistry — Posted on 2024-08-29

349 Structural understanding of NtcA regulation and of its coactivation by the adaptor PII/NtcA shuttling protein PipX, which connects PII regulation with gene expression regulation

Forcada-Nadal, A.; Bibak, S.; Salinas, P.; Contreras, A.; Rubio, V.; Llacer, J. L.

10.1101/2024.08.29.607757 — biochemistry — Posted on 2024-08-29

350 Diverse RNA Structures Induce PRC2 Dimerization and Inhibit Histone Methyltransferase Activity

Song, J.; Yao, L.; Gooding, A. R.; Thron, V.; Kasinath, V.; Cech, T. R.

10.1101/2024.08.29.610323 — biochemistry — Posted on 2024-08-29

351 Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid-protein interaction sites by mass spectrometry

Welp, L. M.; Sachsenberg, T.; Wulf, A.; Chernev, A.; Horokhovskyi, Y.; Neumann, P.; Pasen, M.; Siraj, A.; Raabe, M.; Johannsson, S.; Schmitzova, J.; Netz, E.; Pfeuffer, J.; He, Y.; Fritzemeier, K.; Delanghe, B.; Viner, R.; Vos, S.; Cramer, P.; Ficner, R.; Liepe, J.; Kohlbacher, O.; Urlaub, H.

10.1101/2024.08.29.610268 — biochemistry — Posted on 2024-08-29

352 Structural and systems characterization of phosphorylation on metabolic enzymes identifies sex-specific metabolic reprogramming in obesity

Tamir, T. Y.; Chaudhary, S.; Li, A. X.; Trojan, S. E.; Flower, C. T.; Vo, P.; Cui, Y.; Davis, J. C.; Mukkamala, R. S.; Venditti, F. N.; Hillis, A. L.; Toker, A.; Vander Heiden, M. G.; Spinelli, J. B.; Kennedy, N. J.; Davis, R. J.; White, F. M.

10.1101/2024.08.28.609894 — biochemistry — Posted on 2024-08-29

353 The C2 domain augments Ras GTPase Activating Protein catalytic activity

Paul, M. E.; Chen, D.; Vish, K. J.; Lartey, N. L.; Hughes, E.; Freeman, Z. T.; Saunders, T.; Stiegler, A. L.; King, P. D.; Boggon, T. J.

10.1101/2024.08.29.609784 — biochemistry — Posted on 2024-08-29

354 Energy filtering enables macromolecular MicroED data at sub-atomic resolution

Clabbers, M. T. B.; Hattne, J.; Martynowycz, M. W.; Gonen, T.

10.1101/2024.08.29.610380 — biochemistry — Posted on 2024-08-29

355 A Hybrid Type I and II Polyketide Synthases Yields Distinct Aromatic Polyketides

Zhao, L. Y.; Shi, J.; Xu, Z. Y.; Sun, J. L.; Yan, Z. Y.; Tong, Z. W.; Tan, R. X.; Jiao, R. H.; Ge, H. M.

10.1101/2024.08.28.610196 — biochemistry — Posted on 2024-08-29

356 Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq

Forino, N. M.; Woo, J. Z.; Zaug, A. J.; Jimenez, A. G.; Edelson, E.; Cech, T. R.; Rouskin, S.; Stone, M.

10.1101/2023.10.04.560962 — biochemistry — Posted on 2024-08-29

357 Genetic regulation of nascent RNA maturation revealed by direct RNA nanopore sequencing

Choquet, K.; Chaumont, L.-P.; Bache, S.; Baxter-Koenigs, A. R.; Churchman, L. S.

10.1101/2024.08.29.610338 — genomics — Posted on 2024-08-29

358 DNA replication in primary hepatocytes without the six-subunit ORC

Przanowska, R. K.; Chen, Y.; Uchida, T. O.; Shibata, E.; Hao, X.; Rueda, I. S.; Jensen, K.; Przanowski, P.; Trimboli, A.; Shibata, Y.; Leone, G.; Dutta, A.

10.1101/2024.04.04.588006 — genetics — Posted on 2024-08-29

359 Trait-space disparity in fish communities spanning 380 million years from the Late Devonian to present

Llewelyn, J. S.; Long, J. A.; Cloutier, R.; Clement, A. M.; Strona, G.; Saltre, F.; Lee, M. S. Y.; Choo, B.; Trinajstic, K.; Vanhaesebroucke, O.; Bradshaw, C. J. A.

10.1101/2024.08.29.610219 — evolutionary biology — Posted on 2024-08-29

360 PKA prevents resection of DNA double strand breaks and favor non-homologous end-joining

Khater-Sellou, H.; Magdalou, I.; Ogryzko, V.; Lopez, B. S.

10.1101/2024.08.29.610313 — molecular biology — Posted on 2024-08-29

361 Development of a Robust Gel-Free 3D Culture System for Generating Spheroids from Axolotl Blastema Cells

Aladag, Z.; vatandaslar, E.; Vilain, S.; Ozturk, G.

10.1101/2024.08.29.610223 — molecular biology — Posted on 2024-08-29

362 Investigating the p21 Ubiquitin-Independent Degron Reveals a Dual Degron Module Regulating p21 Degradation and Function.

Riutin, M.; Erez, P.; Adler, J.; Biran, A.; Myers, N.; Shaul, Y.

10.1101/2024.08.29.610237 — molecular biology — Posted on 2024-08-29

363 ONE-STEP tagging: a versatile method for rapid site-specificintegration by simultaneous reagent delivery

Migliori, V.; Bruntraeger, M.; Guylev, I.; Burgold, T.; Lichou, F.; Trinh, A.; Washer, S. J.; Jones, C.; Trynka, G.; Bassett, A. R.

10.1101/2024.08.29.610246 — molecular biology — Posted on 2024-08-29

364 Inferring super-resolved spatial metabolomics from microscopy

Rappez, L.; Haase, K.

10.1101/2024.08.29.610242 — molecular biology — Posted on 2024-08-29

365 Repeat Ascaris challenge reduces worm intensity through gastric cellular reprograming

Wu, Y.; Suarez-Reyes, C.; Kneubehl, A.; Weatherhead, J.

10.1101/2024.08.29.610358 — microbiology — Posted on 2024-08-29

366 RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion

Haase, R.; Ren, B.; Dos Santos Pacheco, N.; Visentin, R.; Maco, B.; Mondragon Flores, R.; Vadas, O.; Soldati-Favre, D.

10.1101/2024.08.29.610260 — microbiology — Posted on 2024-08-29

367 Enhanced Salt Tolerance in Synechocystis sp. PCC 6803 Through Adaptive Evolution: Mechanisms and Applications for Environmental Bioremediation

Zhu, X.; Zou, R.; Liu, D.; Wu, X.; Chen, L.; Sun, T.; Zhang, W.

10.1101/2024.08.29.610226 — microbiology — Posted on 2024-08-29

368 Experimental capture of genomic islands defines a widespread class of genetic element capable of non-autonomous transfer

Zhao, Y.; Ma, Y.; Farr, A. D.; Rogers, D. W.; Rainey, P. B.

10.1101/2024.08.29.610337 — microbiology — Posted on 2024-08-29

369 State-Threatened Gopher Tortoise (Gopherus polyphemus) Gut Microbiome Analysis Reveals Health Insights into Southeastern Florida Population

Giakoumas, D. S.; Mincer, T.; Bernot, K.; Stamper, E.; Moore, J.

10.1101/2024.08.28.609265 — microbiology — Posted on 2024-08-29

370 Sodalis praecaptivus subsp. spalangiae subsp. nov., a nascent bacterial endosymbiont isolated from the parasitoid wasp, Spalangia cameroni

Teh, L. S.; Shalom, S. R.; James, I.; Dolgova, A.; Chiel, E.; Dale, C.

10.1101/2024.08.29.610137 — microbiology — Posted on 2024-08-29

371 Co-zorbs: Motile, multispecies biofilms aid transport of diverse bacterial species

Magesh, S.; Schrope, J.; Mercado-Soto, N.; Li, C.; Hurley, A.; Huttenlocher, A.; Beebe, D. J.; Handelsman, J.

10.1101/2024.08.29.607786 — microbiology — Posted on 2024-08-29

372 RcsF-independent mechanisms of signaling within the Rcs Phosphorelay

Petchiappan, A.; Majdalani, N.; Wall, E.; Gottesman, S.

10.1101/2024.08.29.610257 — microbiology — Posted on 2024-08-29

373 Rab11 suppresses neuronal stress signaling by localizing Dual leucine zipper kinase to axon terminals for protein turnover.

Kim, S.; Quagraine, Y.; Singh, M.; Kim, J. H.

10.1101/2023.04.18.537392 — neuroscience — Posted on 2024-08-29

374 FAIR assessment of MINERVA as an opportunity to foster open science and scientific crowdsourcing in systems biomedicine

Balaur, I.; Welter, D.; Rougny, A.; Inau, E. T.; Mazein, A.; Ghosh, S.; Schneider, R.; Waltemath, D.; Ostaszewski, M.; Satagopam, V.

10.1101/2024.08.28.610042 — systems biology — Posted on 2024-08-29

375 De novo-designed minibinders expand the synthetic biology sensing repertoire

Weinberg, Z. Y.; Soliman, S. S.; Kim, M. S.; Shah, D. H.; Chen, I. P.; Ott, M.; Lim, W. A.; El-Samad, H.

10.1101/2024.01.12.575267 — synthetic biology — Posted on 2024-08-29

376 Optimizing Plant Biofactories: Enhancing Recombinant Protein Production in Nicotiana benthamiana through Phytoplasma Effectors

Rahman, M. S.

10.1101/2024.08.29.610350 — synthetic biology — Posted on 2024-08-29

377 Unveiling the influence of tumor and immune signatures on immune checkpoint therapy in advanced lung cancer

Kim, N.; Park, S.; Jo, A.; Eum, H. H.; Kim, H. K.; Lee, K.; Cho, J. H.; Ku, B. M.; Jung, H. A.; Sun, J.-M.; Lee, S.-H.; Ahn, J. S.; Lee, J.-I.; Choi, J. W.; Jeong, D.; Na, M.; Kang, H.; Kim, J. Y.; Choi, J. K.; Lee, H.-O.; Ahn, M.-J.

10.1101/2024.04.15.589544 — bioinformatics — Posted on 2024-08-29

378 Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2

Nanduri, S.; Black, A.; Bedford, T.; Huddleston, J.

10.1101/2024.02.07.579374 — bioinformatics — Posted on 2024-08-29

379 A bifunctional antibody conjugate marks the location of DNA binding proteins on deproteinized DNA fibers.

Seidman, M.; Shaik, A.; Bellani, M.; Ling, C.; Gali, H.; Pokharel, D.

10.1101/2024.08.29.609705 — biochemistry — Posted on 2024-08-29

380 The influence of sleep disruption on learning and memory in fish

Sowersby, W.; Kobayahsi, T.; Awata, S.; Sogawa, S.; Kohda, M.

10.1101/2024.08.28.610197 — animal behavior and cognition — Posted on 2024-08-29

381 Activity of FoxP2-positive neurons is associated with tadpole begging behavior

Ludington, S. C.; McKinney, J. E.; Butler, J. M.; Goolsby, B. C.; Callan, A. A.; Gaines-Richardson, M.; O'Connell, L. A.

10.1101/2023.05.26.542531 — animal behavior and cognition — Posted on 2024-08-29

382 Fast Low-Input Efficient Hi-C

Guetta, M.; Avidan, N.; Kariti, H.; Davis, L.; Shemer, R.; Elliot, E.; Kaplan, N.

10.1101/2024.08.28.609956 — genomics — Posted on 2024-08-29

383 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.

Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.

10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-29

384 Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium by Reducing Estrogen Receptor Alpha Phosphorylation

Sudeshna Tripathy, S.; Nagari, A.; Chiu, S.-P.; Nandu, T.; Camacho, C. V.; Mahendroo, M.; Kraus, W. L.

10.1101/2024.04.15.589654 — molecular biology — Posted on 2024-08-29

385 DnaA modulates gene expression and morphology of the Lyme Disease spirochete

Krusensjerna, A. C.; Jusufovic, N.; Saylor, T. C.; Stevenson, B.

10.1101/2024.06.08.598065 — microbiology — Posted on 2024-08-29

386 Structural basis for carbohydrate recognition by the Gal/GalNAc lectin of Entamoeba histolytica

Gerard, S. F.; Redfield, C.; Higgins, M. K.

10.1101/2024.08.28.610168 — microbiology — Posted on 2024-08-29

387 Progressive heterogeneity of enlarged and irregularly shaped apicoplasts in P. falciparum persister blood stages after drug treatment

Micchelli, C.; Percopo, C.; Traver, M.; Brzostowski, J.; Amin, S. N.; Prigge, S. T.; Sa, J. M.; Wellems, T.

10.1101/2024.01.03.574077 — microbiology — Posted on 2024-08-29

388 Altered Copper Transport in Oxidative Stress-Dependent Brain Endothelial Barrier Dysfunction Associated with Alzheimer's Disease

Hossain, M. S.; Das, A.; Rafiq, A. M.; Deak, F.; Bagi, Z.; Outlaw, R.; Varadarajan, S.; Yamamoto, M.; Kaplan,, J. H.; Ushio-Fukai, M.; Fukai, T.

10.1101/2024.08.28.610108 — neuroscience — Posted on 2024-08-29

389 FREQuency-resolved brain Network Estimation via Source Separation (FREQ-NESS)

Rosso, M.; Fernandez-Rubio, G.; Keller, P.; Brattico, E.; Vuust, P.; Kringelbach, M. L.; Bonetti, L.

10.1101/2024.08.28.610155 — neuroscience — Posted on 2024-08-29

390 Segregated basal ganglia output pathways correspond to genetically divergent neuronal subclasses

Mendelsohn, A.; Nikoobakht, L.; Bikoff, J.; Costa, R.

10.1101/2024.08.28.610136 — neuroscience — Posted on 2024-08-29

391 Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta

Conrad, W. S.; Oriol, L.; Kollman, G.; Faget, L.; Hnasko, T. S.

10.1101/2024.02.28.582356 — neuroscience — Posted on 2024-08-29

392 Testing retrogenesis and physiological explanations for tract-wise white matter aging: links to developmental order, fibre calibre, and vascularization

Robinson, T. D.; Chad, J. A.; Sun, Y. L.; Chang, P. T. H.; Chen, J. J.

10.1101/2024.01.20.576373 — neuroscience — Posted on 2024-08-29

393 Regulation of transposons within medium spiny neurons enables molecular and behavioral responses to cocaine

Silva, G. M.; Picone, J. A.; Kaplan, A. L.; Park, C. R.; Lira, D. P.; Kim, R. K.; Truby, N. L.; Neve, R. L.; Cui, X.; Hamilton, P. J.

10.1101/2024.08.28.610134 — neuroscience — Posted on 2024-08-29

394 The assembly of cancer-specific ribosomes by the lncRNA LISRR suppresses melanoma anti-tumour immunity

Cinque, S.; Verheyden, Y.; Adnane, S.; Marino, A.; Katopodi, V.; Demesmaeker, E.; Knezevic, Z.; Hanache, S.; Vendramin, R.; Cuomo, A.; Pozniak, J.; Calabuig, A. C.; Tabruyn, S.; Bechter, O.; Baietti, M. F.; Groaz, E.; Bonaldi, T.; Leucci, E.

10.1101/2023.01.06.523012 — cancer biology — Posted on 2024-08-29

395 Ultrasound-activated microbubbles mediate F-actin disruptions and endothelial gap formation during sonoporation

Meijlink, B.; van der Kooij, H. R.; Wang, Y.; Li, H.; Huveneers, S.; Kooiman, K.

10.1101/2024.08.28.610065 — bioengineering — Posted on 2024-08-29

396 Integrative Analysis of Gene Expression, Protein Abundance, and Metabolomic Profiling Elucidates Complex Relationships in Chronic Hyperglycemia-Induced Changes in Human Aortic Smooth Muscle Cells

Bohara, S.; Bagheri, A.; Ertugral, E.; Radzikh, I.; Sandlers, Y.; Jiang, P.; Kothapalli, C.

10.1101/2024.08.28.610153 — bioengineering — Posted on 2024-08-29

397 Hemifusomes and Interacting Proteolipid Nanodroplets: Formation of a Novel Cellular Organelle Complex

Tavakoli, A.; Hu, S.; Ebrahim, S.; Kachar, B.

10.1101/2024.08.28.610112 — cell biology — Posted on 2024-08-29

398 The vprAB-ompV-virK operon of Vibrio cholerae senses antimicrobial peptides and activates the expression of multiple resistance systems

Mathieu-Denoncourt, A.; Whitfield, G. B.; Vincent, A. T.; Pauze-Foixet, J.; Mahieddine, F.; Brun, Y. V.; Duperthuy, M.

10.1101/2024.08.28.609885 — microbiology — Posted on 2024-08-29

399 Mosquitoes reared in distinct insectaries within an institution in close spatial proximity possess significantly divergent microbiome

Brettell, L. E.; Hoque, A. F.; Joseph, T. S.; Dhokiya, V.; Hornett, E. A.; Hughes, G.; Heinz, E.

10.1101/2024.08.28.610121 — microbiology — Posted on 2024-08-29

400 Individual Differences in Cognition and Perception Predict Neural Processing of Speech in Noise for Audiometrically Normal Listeners.

Shehabi, S.; Comstock, D. C.; Mankel, K.; Bormann, B. M.; Das, S.; Brodie, H.; Sagiv, D.; Miller, L. M.

10.1101/2024.08.28.609798 — neuroscience — Posted on 2024-08-29

401 Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture

Burek, D. J.; Mohamad Ibrahim, K.; Hall, A. G.; Sharma, A.; Musiek, E. S.; Moron, J. A.; Carlezon, W. A.

10.1101/2024.08.28.610124 — neuroscience — Posted on 2024-08-29

402 Using in vivo calcium imaging and home cage behavioural analysis to study pain in mouse models of rheumatoid- and osteo-arthritis

Goodwin, G. L.; Marin, A.-C.; Walker, J. V.; Hobbs, C.; Denk, F.

10.1101/2024.08.28.610097 — neuroscience — Posted on 2024-08-29

403 Dissociation of putative open loop circuit from ventral putamen to motor cortical areas in humans I: high-resolution connectomics

Rizor, E. J.; Dundon, N. M.; Wang, J.; Stasiak, J.; Li, T.; Bostan, A.; Lapate, R. C.; Grafton, S. T.

10.1101/2024.08.28.610129 — neuroscience — Posted on 2024-08-29

404 A neural correlate of individual odor preference in Drosophila

Churgin, M.; Lavrentovich, D.; Smith, M. A.-Y.; Gao, R.; Boyden, E. S.; de Bivort, B. L.

10.1101/2021.12.24.474127 — neuroscience — Posted on 2024-08-29

405 Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor (ETI) suggest benefits beyond improved CFTR channel function

Hampton, T. H.; Barnaby, R.; Roche, C.; Nymon, A.; Fukutani, K. F.; MacKenzie, T. A.; Stanton, B. A.

10.1101/2024.08.28.610162 — pharmacology and toxicology — Posted on 2024-08-29

406 Altered functional connectivity and spatiotemporal dynamics in individuals with sleep disorders

Daley, L.; Saini, P.; Watters, H.; Bassil, Y.; Schumacher, E.; Trotti, L. M.; Keilholz, S.

10.1101/2024.08.28.610147 — pathology — Posted on 2024-08-29

407 Scanning probe microscopy elucidates gelation and rejuvenation of biomolecular condensates

Naghilou, A.; Armbruster, O.; Mashaghi, A.

10.1101/2024.08.28.610139 — biophysics — Posted on 2024-08-29

408 Phase behaviour of hnRNPA1 low-complexity domain mutants described by different sequence-dependent models

Feito, A.; Sanchez-Burgos, I. R.; Tejero, I.; Sanz, E.; Rey, A.; Collepardo-Guevara, R.; Tejedor, A. R.; Rene Espinosa, J.

10.1101/2024.08.28.610132 — biophysics — Posted on 2024-08-29

409 DAMP-inducing Peptide Nanofibers and PAMP Combination Adjuvants Boost Functional Lung Tissue-resident Memory CD4+ T Cell Responses

Files, M. A.; Das, A.; Kim, D.; Buck, J. R.; Endsley, J. J.; Rudra, J. S.

10.1101/2024.08.28.610131 — bioengineering — Posted on 2024-08-29

410 Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing

Carrozzo, I.; Maule, G.; Gentile, C.; Umbach, A.; Ciciani, M.; Guidone, D.; De Santis, M.; Petris, G.; Galietta, L. J. V.; Arosio, D.; Cereseto, A.

10.1101/2024.08.28.610115 — bioengineering — Posted on 2024-08-29

411 Single-turnover kinetic analysis of non-LTR retrotransposition defines the mechanism and rate constants governing each step

Dangerfield, T. L.; Zhou, J.; Eickbush, T.; Johnson, K. A. A.

10.1101/2024.08.28.610141 — biochemistry — Posted on 2024-08-29

412 SNAP-tag2: faster and brighter protein labeling

Kühn, S.; Nasufovic, V.; Wilhelm, J.; Kompa, J.; de Lange, E. M. F.; Lin, Y.-H.; Egoldt, C.; Fischer, J.; Lennoi, A.; Tarnawski, M.; Reinstein, J.; Vlijm, R.; Hiblot, J.; Johnsson, K.

10.1101/2024.08.28.610127 — biochemistry — Posted on 2024-08-29

413 Temperature effects on interspecific eavesdropping in the wild

Gray, D.; Fowler-Finn, K. D.; Rossi, S.

10.1101/2024.08.28.610172 — animal behavior and cognition — Posted on 2024-08-29

414 Prefrontal working memory signal primarily controls phase-coded information within extrastriate cortex

Parto-Dezfouli, M.; Vanegas, M. I.; Zarei, M.; Nesse, W. H.; Clark, K. L.; Noudoost, B.

10.1101/2024.08.28.610140 — animal behavior and cognition — Posted on 2024-08-29

415 Profiling extremophile bacterial communities recovered from a mining tailing against soil ecosystems through comparative genome-resolved metagenomics and evolutionary analysis

Rojas, M. A.; Serrano, G.; Torres, J.; Ortega, J.; Galvez, G.; Vilches, E.; Parra, V.; Reyes-Jara, A.; Maracaja-Coutinho, V.; Pizarro, L.; Latorre, M.; Di Genova, A.

10.1101/2024.08.28.610100 — genomics — Posted on 2024-08-29

416 Credible set is sensitive to imputation quality and missing variants

Liang, Y.; 23andMe Research Team, ; Auton, A.; Wang, X.

10.1101/2024.08.28.610135 — genetics — Posted on 2024-08-29

417 Temperature affects recombination rate plasticity and meiotic success between thermotolerant and cold tolerant yeast species

McNeill, J.; Brandt, N.; Schwarzkopf, E. J.; Jimenez Gallardo, M.; Smukowski Heil, C.

10.1101/2024.08.28.610152 — genetics — Posted on 2024-08-29

418 The Role of Metabolic Strategies in Determining Microbial Community Diversity along Temperature Gradients

Duan, Q.; Clegg, T. E.; Smith, T. P.; Bell, T.; Pawar, S.

10.1101/2024.08.28.610078 — ecology — Posted on 2024-08-29

419 Live Cell Painting: image-based profiling in live cells using Acridine Orange

Garcia-Fossa, F.; Moraes-Lacerda, T.; Rodrigues-da-Silva, M.; Diaz-Rohrer, B.; Singh, S.; Carpenter, A. E.; Cimini, B. A.; de Jesus, M. B.

10.1101/2024.08.28.610144 — cell biology — Posted on 2024-08-29

420 Systematic deletion of symmetrical CFTR exons reveals new therapeutic targets for exon skipping antisense oligonucleotides

Pena-Rasgado, C.; Manriquez, E.; Dundr, M.; Bridges, R. J.; Hastings, M. L.; Michaels, W. E.

10.1101/2024.08.28.607949 — molecular biology — Posted on 2024-08-29

421 O-glycosylation contributes to mammalian glycoRNA biogenesis

Porat, J.; Watkins, C.; Jin, C.; Xie, Y.; Tan, X.; Lebedenko, C.; Hemberger, H.; Shin, W.; Chai, P.; Collins, J. J.; Garcia, B. A.; Bojar, D.; Flynn, R. A.

10.1101/2024.08.28.610074 — molecular biology — Posted on 2024-08-29

422 Linking microbial community structure with function using functional amplicon sequencing of the NRPS genes around wheat roots during drought stress

Guan, Y.; Berne, E.; Hennessy, R. C.; Garbeva, P.; Nicolaisen, M.; Bak, F.

10.1101/2024.08.28.609728 — microbiology — Posted on 2024-08-29

423 A two-dose regimen of Qβ virus-like particle-based vaccines elicit protective antibodies against heroin and fentanyl

Romano, I. G.; Johnson-Weaver, B. T.; Core, S. B.; Jamus, A. N.; Brackeen, M.; Blough, B.; Dey, S.; Huang, Y.; Staats, H. F.; Wetsel, W. C.; Chackerian, B.; Frietze, K. M.

10.1101/2024.08.28.608988 — immunology — Posted on 2024-08-29

424 Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signalling in Drosophila

Vincze, V.; Esküdt, Z.; Feher-Juhasz, E.; Chhatre, A. S.; Jipa, A.; Csordos, M.; Galambos, A. R.; Börcsök, D.; Juhasz, G.; Szabo, A.

10.1101/2024.08.28.610109 — neuroscience — Posted on 2024-08-29

425 Glutamate uptake is transiently compromised in the perilesional cortex following controlled cortical impact

Garcia, J. P.; Armbruster, M.; Sommer, M.; Nunez-Beringer, A.; Dulla, C. G.

10.1101/2024.08.28.610143 — neuroscience — Posted on 2024-08-29

426 Region-specific Nucleus Accumbens Dopamine Signals Encode Distinct Aspects of Avoidance Learning

Lopez, G. C.; Van Camp, L. D.; Kovaleski, R. F.; Schaid, M. D.; Moreno-Ramos, O. A.; Awatramani, R.; Cox, J. M.; Lerner, T. N.

10.1101/2024.08.28.610149 — neuroscience — Posted on 2024-08-29

427 Headache-specific Hyperexcitation Sensitises and Habituates on different Time Scales: An Event Related Potential study of Pattern-Glare

Dogan, C.; Miller, C. E.; Jefferis, T.; Saranti, M.; Tempesta, A.; Scofield, A.; Ramaswamy, P.; Bowman, H.

10.1101/2024.08.28.610154 — neuroscience — Posted on 2024-08-29

428 Handy divisions: Hand-specific specialization of prehensile control in bimanual tasks

Naik, A.; Ambike, S.

10.1101/2024.08.28.610133 — neuroscience — Posted on 2024-08-29

429 Responses of root architectural and anatomical traits to low nitrogen stress in rice

Brown, K.; Lynch, J.; Tian, T.

10.1101/2024.08.28.610142 — plant biology — Posted on 2024-08-29

430 Ethylene sensitivity assay for medicinal and fiber-type Cannabis seedlings reveals a triple-response-like phenotype

Monthony, A. S.; Ledeuil, M.; Torkamaneh, D.

10.1101/2024.08.28.610146 — plant biology — Posted on 2024-08-29

431 AMOEBA Polarizable Molecular Dynamics Simulations of Guanine Quadruplexes: from the c-Kit Proto-oncogene to HIV-1

El Ahdab, D. S.; Lagardere, L.; Hobaika, Z.; Jaffrelot Inizan, T.; Celerse, F.; Gresh, N.; Maroun, R. G.; Piquemal, J.-P.

10.1101/2024.08.28.610081 — biophysics — Posted on 2024-08-29

432 Auditory feedback effect of self-pacing treadmill walking in comparison to overground walking

Evans, T.; Reissman, M. E.; Reissman, T.; Shelhamer, M.; Chaudhari, A. M. W.

10.1101/2024.08.28.610096 — bioengineering — Posted on 2024-08-29

433 Investigation of Lipid-PEG Anchorage of Proteins onto Mesenchymal Stem Cell Derived Extracellular Vesicles for Intracellular Delivery: A Quantitative Assessment

Marquant, A.; Berthelot, J.; Bich, C.; Ibn Elfekih, Z.; Simon, L.; Robin, B.; Chopineau, J.; Tianpei Wang, D.; Jay Emerson, S.; Wang, A.; Benedetti, C.; Langlois, S.; Guglielmi, L.; Martineau, P.; Aubert-Pouessel, A.; Morille, M.

10.1101/2024.08.28.610030 — bioengineering — Posted on 2024-08-29

434 Toward the Clinical Translation of Safe Intravenous Long Circulating Iodinated Lipid Nanoemulsion Contrast Agents for CT Imaging

Attia, M. F.; Marasco, R. N.; Kwain, S.; Foxx, C.; Whitehead, D. C.; Kabanov, A.; Lee, Y. Z.

10.1101/2024.08.28.610138 — bioengineering — Posted on 2024-08-29

435 Extinction burst could be explained by curiosity-driven reinforcement learning

Yamada, K.; Matsui, H.; Toda, K.

10.1101/2024.08.28.610088 — animal behavior and cognition — Posted on 2024-08-29

436 Charting the Silent Signals of Social Gaze: Automating Eye Contact Assessment in Face-to-Face Conversations

Schmaelzle, R.; Jahn, N. T.; Bente, G. M.

10.1101/2024.08.28.610064 — animal behavior and cognition — Posted on 2024-08-29

437 Number of ancestors and length of identity-by-descent tracks over time

Eriksen, M. S.; Renaud, G.

10.1101/2024.08.28.610091 — genomics — Posted on 2024-08-29

438 Quantifying immune cell telomere content at single-cell resolution in context of PD-1 checkpoint immunotherapy

Engel, N. L.; Herzel, L.; Surmely, J.; Friess, H.; Simon, M.; Brors, B.; Imbusch, C.; Feuerbach, L.

10.1101/2024.08.28.609339 — immunology — Posted on 2024-08-29

439 Mouse olfactory system acts as anemo-detector and -discriminator

Mahajan, S.; Tamboli, S.; Das, S.; Bhattacharjee, A. S.; Pardasani, M.; Srikanth, P.; Marathe, S. D.; Adlakha, A.; Ranjan, L.; Pandey, S.; Abraham, N. M.

10.1101/2024.08.28.610087 — neuroscience — Posted on 2024-08-29

440 Phylogenomics of a genus of "Great Speciators" reveals rampant incomplete lineage sorting, gene flow, and mitochondrial capture in island systems

McCullough, J.; Eliason, C.; Hackett, S. J.; Myers, C. E.; Andersen, M. J.

10.1101/2024.08.28.610082 — zoology — Posted on 2024-08-29

441 Prevalence of Problematic Papers in Non-Coding RNA Research

Lou, Y.; Zhou, Z.; Li, M.; Shen, Z.

10.1101/2024.08.28.607530 — molecular biology — Posted on 2024-08-29

442 Dopamine and temporal discounting: revisiting pharmacology and individual differences

Smith, E.; Theis, H.; van Eimeren, T.; Knauth, K.; Tuzsus, D.; Zhang, L.; Mathar, D.; Peters, J.

10.1101/2024.08.28.610170 — neuroscience — Posted on 2024-08-29

443 'Eye Know': Gaze reflects confidence in explicit predictions while relying on a distinct computational mechanism

Stern, Y.; Netzer, O.; Koren, D.; Zvilichovsky, Y.; Hertz, U.; Salomon, R.

10.1101/2024.08.28.610145 — neuroscience — Posted on 2024-08-29

444 Discovery of natural compounds as novel FMS-like tyrosine kinase 3 (FLT3) therapeutic inhibitors for the treatment of acute myeloid leukemia: an in silico approach

Das, U.; C, L.; Uttarkar, A.; Kumar, J.; Niranjan, V.

10.1101/2024.08.27.609927 — bioinformatics — Posted on 2024-08-29

445 In silico Exploration Natural Compounds for the Discovery of Novel DNMT3A Inhibitors as Potential Therapeutic Agents for Acute Myeloid Leukemia

Das, U.; Uttarkar, A.; Kumar, J.; Niranjan, V.

10.1101/2024.08.28.610083 — bioinformatics — Posted on 2024-08-29

446 Genotyping sequence-resolved copy-number variation using pangenomes reveals paralog-specific global diversity and expression divergence of duplicated genes

Ma, W.; Chaisson, M.

10.1101/2024.08.11.607269 — genomics — Posted on 2024-08-29

447 Colonisation lags predict sympatric diversity in birds

Reijenga, B. R.; Etienne, R. S.; Murrell, D. J.; Pigot, A. L.

10.1101/2024.08.28.610044 — evolutionary biology — Posted on 2024-08-29

448 Peripheral nervous system mediates body-wide stem cell activation for limb regeneration

Payzin-Dogru, D.; Blair, S. J.; Jena, S. G.; Wilson, S. E.; Kim, R. T.; Savage, A. M.; Kriukov, E.; Cat, V.; Cammarata, L. V.; Bothe, V.; Erdogan, B.; Hossain, S.; Lopez, N.; Losner, J.; Velazquez Matos, J. C.; Min, S.; Dooling, K. E.; Freedman, A. H.; Groves, B.; Tajer, B.; Kalu, G.; Wynn, E.; Wong, A. Y. L.; Singer, H.; Frobisch, N.; Baranov, P.; Buenrostro, J. D.; Haas, B. J.; Chiu, I. M.; Sackton, T. B.; Whited, J. L.

10.1101/2021.12.29.474455 — developmental biology — Posted on 2024-08-29

449 Microglia cannibalism and efferocytosis leads to shorter lifespans of developmental microglia

Gordon, H.; Schafer, Z. T.; Smith, C. J.

10.1101/2023.03.15.532426 — developmental biology — Posted on 2024-08-29

450 HIRA defines early replication initiation zones independently of their genome compartment

Karagyozova, T.; Gatto, A.; Forest, A.; Quivy, J.-P.; Marti-Renom, M. A.; Mirny, L.; Almouzni, G.

10.1101/2024.08.29.610220 — cell biology — Posted on 2024-08-29

451 CRISPR/dCas-mediated counter-silencing: Reprogramming dCas proteins into antagonists of xenogeneic silencers

Wiechert, J.; Badia Poige, B.; Dohmen-Olma, D.; Hindra, ; Zhang, X.; Elliot, M.; Frunzke, J.

10.1101/2024.08.29.610263 — microbiology — Posted on 2024-08-29

452 Columnar cholinergic neurotransmission onto T5 cells of Drosophila

Samara, E.; Schilling, T.; Ribeiro, I. M. A.; Haag, J.; Leonte, M.-B.; Borst, A.

10.1101/2024.08.28.610055 — neuroscience — Posted on 2024-08-29

453 Synaptic connectome of a neurosecretory network in the Drosophila brain

McKim, T. H.; Gera, J.; Gayban, A. J.; Reinhard, N.; Manoli, G.; Hilpert, S.; Helfrich-Forster, C.; Zandawala, M.

10.1101/2024.08.28.609616 — neuroscience — Posted on 2024-08-29

454 Age Dependent Integration of Cortical Progenitors Transplanted at the Adult CSF-Brain Interface

Pothayee, N.; Greene, G.; Jahanipour, J.; Jie, H.; Tao-Cheng, J.-H.; Petrus, E.; Maric, D.; Koretsky, A. P.

10.1101/2024.08.28.609860 — neuroscience — Posted on 2024-08-29

455 Variations of neuronal properties in the region of locus coeruleus of mice

Tortorelli, L.; Garad, M.; Megemont, M.; Haga-Yamanaka, S.; Goel, A.; Yang, H.

10.1101/2022.08.19.504582 — neuroscience — Posted on 2024-08-29

456 Repeated Sub-anaesthetic dose of Ketamine Elevates Superoxide Dismutase in Pharmacological Model of Schizophrenia-Like Phenotypes in Mice

Usman, Y.; Aderibigbe, A. O.; Fehintola, F. A.

10.1101/2024.08.28.610179 — neuroscience — Posted on 2024-08-29

457 The transaminase-omega-amidase pathway is a redox switch in glutamine metabolism that generates alpha-ketoglutarate

Herrle, N.; Felipe Malacarne, P.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; S. Leisegang, M.; Sarakpi, T.; Wionski, S.; Lopez, M.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Guenther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Wittig, I.; H. Schulz, M.; Richards, J. B.; Gilsbach, R.; T. Denton, T.; Fleming, I.; Hannibal, L.; P. Brandes, R.; Rezende, F.

10.1101/2024.08.28.610061 — physiology — Posted on 2024-08-29

458 Selective autophagy of ribosomes balances a tradeoff between starvation survival and growth resumption

Tuomaala, J.; Sankar, D. S.; Perey, J.; Psalmon, S.; Stroustrup, N.; Dengjel, J.; Towbin, B. D.

10.1101/2024.08.28.609383 — physiology — Posted on 2024-08-29

459 Crowder induced conformational fluctuations modulate the phase separation of yeast SUP35 NM domain

Chattopadhyay, K.; Roychowdhury, S.; Menon, S.; Mandal, N.; Mondal, J.

10.1101/2024.08.28.610075 — biophysics — Posted on 2024-08-29

460 simona: a comprehensive R package for semantic similarity analysis on bio-ontologies

Gu, Z.

10.1101/2023.12.03.569758 — bioinformatics — Posted on 2024-08-29

461 Topology-Driven Negative Sampling Enhances Generalizability in Protein-Protein Interaction Prediction

Chatterjee, A.; Ravandi, B.; Haddadi, P.; Philip, N. H.; Abdelmessih, M.; Mowrey, W. R.; Ricchiuto, P.; Liang, Y.; Ding, W.; Mobarec, J. C.; Eliassi-Rad, T.

10.1101/2024.04.27.591478 — bioinformatics — Posted on 2024-08-29

462 Is this scenery worth exploring? Insight into the visual encoding of navigating ants.

CLEMENT, L.; Schwarz, S.; Mahot-Castaing, B.; Wystrach, A.

10.1101/2024.08.28.610048 — animal behavior and cognition — Posted on 2024-08-29

463 EdgeHOG: fine-grained ancestral gene order inference at tree-of-life scale

Bernard, C.; Nevers, Y.; Karampudi, N. B. R.; Gilbert, K. J.; Train, C.; Vesztrocy, A. W.; Glover, N.; Altenhoff, A.; Dessimoz, C.

10.1101/2024.08.28.610045 — evolutionary biology — Posted on 2024-08-29

464 How Alzheimer's Abeta propagates and triggers tau pathology in intact neurons

Sasahara, T.; Hongo, S.; Ito, M.; Takino, N.; Muramatsu, S.-i.; Kakita, A.; Hoshi, M.

10.1101/2024.08.28.608712 — neuroscience — Posted on 2024-08-29

465 Postural demands modulate tactile perception in the lower limb in young and older adults

Wachsmann, F. D.; Fiehler, K.; Voudouris, D.

10.1101/2024.08.28.610073 — neuroscience — Posted on 2024-08-29

466 Does slow oscillation-spindle coupling contribute to sleep-dependent memory consolidation? A Bayesian meta-analysis

Ng, T.; Noh, E.; Spencer, R. M. C.

10.1101/2024.08.28.610060 — neuroscience — Posted on 2024-08-29

467 CDKL5's role in microtubule-based transport and cognitive function

Lopes, A. T.; Janiv, O.; Claxton, S.; Ultanir, S. K.

10.1101/2024.08.28.610038 — neuroscience — Posted on 2024-08-29

468 Expanding the toolbox: Novel class IIb microcins show activity against gram-negative ESKAPE and plant pathogens

Mortzfeld, B. M.; Bhattarai, S. K.; Bucci, V.

10.1101/2023.12.05.570296 — microbiology — Posted on 2024-08-29

469 Extending the IICR to multiple genomes and identification of limitations of some demographic inferential methods

Chikhi, L.; Rodriguez, W.; Paris, C.; Ha-Shan, M.; Jouniaux, A.; Arredondo, A.; Nous, C.; Grusea, S.; Corujo, J.; Lourenco, I.; Boitard, S.; Mazet, O.

10.1101/2024.08.16.608273 — evolutionary biology — Posted on 2024-08-29

470 Resistance and resilience of soil microbiomes under climate change

Boyle, J. A.; Murphy, B. K.; Ensminger, I.; Stinchcombe, J. R.; Frederickson, M. E.

10.1101/2023.08.04.551981 — ecology — Posted on 2024-08-29

471 Transferability of ecological forecasting models to novel biotic conditions in a long-term experimental study

Dumandan, P. K. T.; Simonis, J.; Yenni, G. M.; Ernest, S. K. M.; White, E.

10.1101/2023.11.01.565145 — ecology — Posted on 2024-08-29

472 miR-146a-5p mediates inflammation-induced β cell mitochondrial dysfunction and apoptosis

Krishnan, P.; Branco, R. C. S.; Weaver, S. A.; Chang, G.; Lee, C.-C.; Syed, F.; Evans-Molina, C.

10.1101/2024.03.18.585543 — molecular biology — Posted on 2024-08-29

473 GABA-ergic inhibition in human hMT+ predicts visuo-spatial intelligence mediated through the frontal cortex

Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.

10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-08-29

474 Single-Cell Stress Analysis in Tumoroids.

Rodrigues de Mercado, R.; Beslmuller, K.; Vorselen, D.; Danen, E.; Schmidt, T.

10.1101/2024.01.22.576025 — biophysics — Posted on 2024-08-29

475 CFAP410 has a bimodular architecture with a conserved surface patch on its N-terminal LRR motif for binding interaction partners

Stadler, A.; Gabriel, H. B.; De Liz, L. V.; Alonso-Gil, S.; Deng, X.; Crickley, R.; Korbula, K.; Huang, K.; Zagrovic, B.; Vaughan, S.; Sunter, J.; Dong, G.

10.1101/2022.09.21.508879 — biochemistry — Posted on 2024-08-29

476 The evolutionary dynamics of locally adaptive chromosome inversions in Mimulus guttatus

Kollar, L. M.; Stanley, L. E.; Kenchanmane Raju, S. K. M.; Lowry, D.; Niederhuth, C. E.

10.1101/2023.12.06.570460 — genomics — Posted on 2024-08-29

477 Laminin gamma1-dependent basement membranes are instrumental to ensure proper olfactory placode shape, position and boundary with the brain, as well as olfactory axon development

Tignard, P.; Pottin, K.; Geeverding, A.; Doulazmi, M.; Cabrera, M.; Fouquet, C.; Liffran, M.; Fouchard, J.; Rosello, M.; Albadri, S.; Del Bene, F.; Trembleau, A.; Breau, M. A.

10.1101/2023.06.29.547040 — developmental biology — Posted on 2024-08-29

478 Control of Clostridiodes difficile virulence and physiology by the flagellin homeostasis checkpoint FliC-FliW-CsrA in the absence of motility

Zhu, D.; Wozniak, K.; Midani, F. S.; Wang, S.; Sun, X.; Britton, R.

10.1101/2022.11.08.515568 — microbiology — Posted on 2024-08-29

479 The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2

Suryawanshi, R. K.; Jaishankar, P.; Correy, G. J.; Rachman, M. M.; O'Leary, P. C.; Taha, T. Y.; Zapatero-Belinchon, F. J.; McCavitt-Malvido, M.; Doruk, Y. U.; Stevens, M. G. V.; Diolaiti, M. E.; Jogalekar, M. P.; Richards, A. L.; Montano, M.; Rosecrans, J.; Matthay, M.; Togo, T.; Gonciarz, R. L.; Gopalkrishnan, S.; Neitz, R. J.; Krogan, N. J.; Swaney, D. L.; Shoichet, B. K.; Ott, M.; Renslo, A. R.; Ashworth, A.; Fraser, J. S.

10.1101/2024.08.08.606661 — immunology — Posted on 2024-08-29

480 Oscillatory multi-timescale mechanisms underlying multisensory sequence prediction

Wang, P.; Maye, A.; Daume, J.; Xue, G.; Engel, A. K.

10.1101/778969 — neuroscience — Posted on 2024-08-29

481 Functional divergence of conserved developmental plasticity genes between two distantly related nematodes

Wighard, S.; Witte, H.; Sommer, R. J.

10.1101/2024.08.29.610235 — evolutionary biology — Posted on 2024-08-29

482 Dietary zinc limitation dictates lifespan and reproduction trade-offs of Drosophila mothers

Sarmah, S.; Piper, M. D. W.; Mirth, C.; Burke, R.; McColl, G.; Truong, H. H. T. H. T.

10.1101/2024.08.28.610171 — evolutionary biology — Posted on 2024-08-29

483 The influence of sleep disruption on learning and memory in fish

Sowersby, W.; Kobayahsi, T.; Awata, S.; Sogawa, S.; Kohda, M.

10.1101/2024.08.28.610197 — animal behavior and cognition — Posted on 2024-08-29

484 GENETIC VARIABILITY AND ASSOCIATION OF TRAITS IN COMMON BEAN (Phaseolus vulgaris L.) GENOTYPES IN SEKOTA, NORTH WESTERN ETHIOPIA

Assefa, A. G.; worku, D.; Bantayhu, M.; Asres, F.

10.1101/2024.08.21.609046 — scientific communication and education — Posted on 2024-08-29

485 Intestinal microbiome dysbiosis increases Mycobacteria pulmonary colonization in mice by regulating the Nos2-associated pathways

Han, M.; Wang, X.; Su, L.; Pan, S.; Liu, N.; Li, D.; Liu, L.; Cui, J.; Zhao, H.; Yang, F.

10.1101/2024.05.09.593309 — microbiology — Posted on 2024-08-29

486 Individualized functional localization of the language and multiple demand network in chronic post-stroke aphasia

De Clercq, P.; Gonsalves, A. R.; Gerrits, R.; Vandermosten, M.

10.1101/2024.01.12.575350 — neuroscience — Posted on 2024-08-29

487 Genomic and transcriptomic profiles influence on brain morphology and their interactions with pain sensitivity individual differences

Pan, Y.; Zhang, Z.; Hao, X.; Huang, G.; Liang, Z.; Zhang, L.

10.1101/2024.07.30.605795 — bioinformatics — Posted on 2024-08-29

488 MethylBERT: A Transformer-based model for read-level DNA methylation pattern identification and tumour deconvolution

Jeong, Y.; Gerhauser, C.; Sauter, G.; Schlomm, T.; Rohr, K.; Lutsik, P.

10.1101/2023.10.29.564590 — bioinformatics — Posted on 2024-08-29

489 Peptide therapeutic leads for multi-target inhibition of inflammatory cytokines in Inflammatory Bowel Disease - computational design and in-vitro validation

Tsaban, T.; Kariv-Attias, G.; Khramushin, A.; Gover, O.; Hayouka, Z.; Schueler-Furman, O.; Schwartz, B.

10.1101/2024.08.27.609829 — bioinformatics — Posted on 2024-08-29

490 Experimental evolution of Escherichia coli on solid silver, copper, stainless steel, and glass surfaces

Rosenberg, M.; Park, S.; Umerov, S.; Ivask, A.

10.1101/2024.06.06.597739 — microbiology — Posted on 2024-08-29

491 Theta oscillations optimize a speed-precision trade-off in phase coding neurons

Amil, A. F.; Albesa-Gonzalez, A.; Verschure, P. F. M. J.

10.1101/2022.12.08.519523 — neuroscience — Posted on 2024-08-29

492 Microtubule-based nucleation results in a large sensitivity to cell geometry of the plant cortical array

Saltini, M.; Deinum, E. E.

10.1101/2024.03.25.586463 — biophysics — Posted on 2024-08-29

493 Flexible reproductive seasonality in Africa-dwelling papionins is associated with low environmental productivity and high climatic unpredictability

Dezeure, J.; Dagorrette, J.; Burtschell, L.; Chowdhury, S.; Lukas, D.; Swedell, L.; Huchard, E.

10.1101/2024.05.01.591991 — evolutionary biology — Posted on 2024-08-29

494 Clouds, oases for airborne microbes - Differential metagenomics/ metatranscriptomics analyses of cloudy and clear atmospheric situations

Peguilhan, R.; Rossi, F.; Joly, M.; Nasr, E.; Batut, B.; Enault, F.; Ervens, B.; Amato, P.

10.1101/2023.12.14.571671 — ecology — Posted on 2024-08-29

495 Spatial Dynamics of the Developing Human Heart

Lazar, E.; Mauron, R.; Andrusivova, Z.; Foyer, J.; He, M.; Larsson, L.; Shakari, N.; Salas, S. M.; Avenel, C.; Sariyar, S.; Hansen, J. N.; Vicari, M.; Czarnewski, P.; Braun, E.; Li, X.; Bergmann, O.; Sylven, C.; Lundberg, E.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Adameyko, I.; Lundeberg, J.

10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-08-29

496 Strigolactone receptor DAD2 promotes lateral root formation in Petunia hybrida

Khuvung, K.; Courty, P.-E.; Reinhardt, D.

10.1101/2024.08.28.609930 — plant biology — Posted on 2024-08-29

497 GageTracker: a tool for dating gene age by micro- and macro-synteny with high speed and accuracy

Fang, C.; Dong, C.; Wang, C.; Xiong, F.; Lu, S.; Fang, W.; Li, T.; Gan, X.; Yang, L.; Zeng, H.; He, S.

10.1101/2024.08.28.610050 — bioinformatics — Posted on 2024-08-29

498 PICASO: Profiling Integrative Communities of Aggregated Single-cell Omics data

Joppich, M.; Kramann, R.; Hayat, S.

10.1101/2024.08.28.610120 — bioinformatics — Posted on 2024-08-29

499 Behavioral pharmacology of mescaline - the role of serotonin 5-HT2A, 5-HT2B, 5-HT2C and 5-HT1A receptors

Olejnikova-Ladislavova, L.; Fujakova-Lipski, M.; Sichova, K.; Danda, H.; Syrova, K.; Horacek, J.; Palenicek, T.

10.1101/2024.08.28.610032 — animal behavior and cognition — Posted on 2024-08-29

500 Cellular processing of beneficial de novo emerging proteins

Houghton, C. J.; Castilho Coelho, N.; Chiang, A.; Hedayati, S.; Parikh, S. B.; Ozbaki-Yagan, N.; Wacholder, A.; Iannotta, J.; Berger, A.; Carvunis, A.-R.; O'Donnell, A. F.

10.1101/2024.08.28.610198 — evolutionary biology — Posted on 2024-08-29

501 Exploration of Natural Products for Targeting IDH1/2 Mutations in Acute Myeloid Leukemia through Ligand-Based Pharmacophore Screening, Docking, ADME-T and Molecular Dynamic Simulation Approaches

Das, U.; Regati, D. R.; Kumar, J.; Sowdhamini, R.

10.1101/2024.08.27.609840 — bioinformatics — Posted on 2024-08-29

502 A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development - which one is better?

Gardner, P. P.

10.1101/2024.08.25.609622 — bioinformatics — Posted on 2024-08-29

503 OPUS-Design: Designing Protein Sequence from Backbone Structure with 3DCNN and Protein Language Model

Xu, G.; Yang, Y.; Zhang, Y.; Wang, Q.; Ma, J.

10.1101/2024.08.20.608889 — bioinformatics — Posted on 2024-08-29

504 VISTA Uncovers Missing Gene Expression and Spatial-induced Information for Spatial Transcriptomic Data Analysis

Liu, T.; Lin, Y.; Luo, X.; Sun, Y.; Zhao, H.

10.1101/2024.08.26.609718 — bioinformatics — Posted on 2024-08-29

505 Accurate antibody loop structure prediction enables zero-shot design of target-specific antibodies

Bang, Y.; Choi, Y.-A.; Gu, J.; Kwon, S.; Lee, D.; Lee, E. S.; Lee, M. S.; Lee, S.; Lee, S.; Lee, S. J.; Lim, J.; Maeng, J. Y.; Nam, J.; Noh, J.; Oh, H.; Park, S.-Y.; Park, T.; Seo, S.; Seok, C.; Song, M. Y.; Won, J.; Woo, H.; Yang, J.; Yoon, M. J.; Bae, W.; Kim, J.; Lee, D.; Lee, J.; Lee, Y.; Yu, H.

10.1101/2024.08.23.609114 — bioengineering — Posted on 2024-08-29

506 Evolution of a Eukaryotic Transcription Factor's co-TF Dependence Involves Multiple Intrinsically Disordered Regions Affecting Activation and Autoinhibition

Snyder, L. F.; O'Brien, E. M.; Zhao, J.; Liang, J.; Zhang, Y.; Zhu, W.; Cassier, T.; Schnicker, N. J.; Zhou, X.; Gordan, R.; He, B. Z.

10.1101/2024.04.20.590343 — evolutionary biology — Posted on 2024-08-29

507 Weak Relationship Between Divergence and Selection in a North American Toad Hybrid Zone

Cobb, K. A.; Oaks, J. R.

10.1101/2024.08.09.606439 — evolutionary biology — Posted on 2024-08-29

508 The Fossilised Birth-Death Model is Identifiable

Truman, K.; Vaughan, T. G.; Gavryushkin, A.; Gavryushkina, A.

10.1101/2024.02.08.579547 — evolutionary biology — Posted on 2024-08-29

509 Plasticity, geographic variation and trait coordination in blue oak drought physiology

Anderegg, L. D. L.; Skelton, R. P.; Diaz, J.; Papper, P.; Ackerly, D. D.; Dawson, T. D. L.

10.1101/2023.08.20.553748 — ecology — Posted on 2024-08-29

510 Marine spatial planning to enhance coral adaptive potential

Forrest, D. L.; McManus, L. C.; Tekwa, E. W.; Schindler, D. E.; Colton, M. A.; Webster, M. M.; Fox, H. E.; Essington, T. E.; Palumbi, S. R.; Mumby, P. J.; DeFilippo, L.; Schill, S. R.; Pollock, F. J.; Pinsky, M. L.

10.1101/2024.08.27.609972 — ecology — Posted on 2024-08-29

511 Animal septins contain functional transmembrane domains

Perry, J. A.; Werner, M. E.; Omi, S.; Heck, B. W.; Maddox, P. S.; Mavrakis, M.; Maddox, A. S.

10.1101/2023.11.20.567915 — cell biology — Posted on 2024-08-29

512 Bacterial defense and phage counter-defense lead to coexistence in a modeled ecosystem

Kimchi, O.; Meir, Y.; Wingreen, N. S.

10.1101/2024.07.17.603905 — microbiology — Posted on 2024-08-29

513 Selective Effects of Ongoing Alpha-Band Activity on Magno- and Parvo-Mediated Detection

Pilipenko, A.; Samaha, J.

10.1101/2024.07.28.605527 — neuroscience — Posted on 2024-08-29

514 Radiation of pain: Psychophysical evidence for a population coding mechanism in humans

Adamczyk, W. M.; Ramu, V.; Jackson, C.; Schulze, G.; Goldschneider, K.; Kashikar-Zuck, S.; King, C.; Coghill, R. C.

10.1101/2024.04.02.587666 — neuroscience — Posted on 2024-08-29

515 Sex-specific loss of mitochondrial membrane integrity in the auditory brainstem of a mouse model of Fragile X syndrome

Caron, C.; McCullagh, E. A.; Bertolin, G.

10.1101/2024.07.02.601649 — neuroscience — Posted on 2024-08-29

516 A multi-channel electrophysiology approach to non-invasively and precisely record human spinal cord activity

Nierula, B.; Stephani, T.; Bailey, E.; Kaptan, M.; Horn, U.; Pohle, L.-M.; Mouraux, A.; Maess, B.; Villringer, A.; Curio, G.; Nikulin, V. V.; Eippert, F.

10.1101/2022.12.05.519148 — neuroscience — Posted on 2024-08-28

517 Oligomerization and positive feedback on membrane recruitment encode dynamically stable PAR-3 asymmetries in the C. elegans zygote.

Lang, C. F.; Maxian, O.; Anneken, A.; Munro, E.

10.1101/2023.08.04.552031 — cell biology — Posted on 2024-08-28

518 SF3B1-mutant mis-splicing of UBA1 confers a targetable therapeutic vulnerability through UBA1 inhibition

Thier, J.; Hofmann, S.; Kirchhof, K.; Todisco, G.; Mortera-Blanco, T.; Barbosa, I.; Björklund, A.-C.; Deslauriers, A. G.; Papaemmanuil, E.; Papapetrou, E. P.; Hellström-Lindberg, E.; Moura, P. L.; Lundin, V.

10.1101/2024.08.28.610114 — cancer biology — Posted on 2024-08-28

519 Comprehensive Database of Circular Permutations: Systematic Detection and Analysis Using Deep Learning

Hu, Y.; Huang, B.

10.1101/2024.08.28.610105 — bioinformatics — Posted on 2024-08-28

520 Involvement of the cerebellum in structural connectivity enhancement in episodic migraine

Matoso, A.; Fouto, A. R.; Esteves, I.; Ruiz-Tagle, A.; Caetano, G.; da Silva, N. A.; Vilela, P.; Gil-Gouveia, R.; Nunes, R. G.; Figueiredo, P.

10.1101/2024.04.26.591265 — bioengineering — Posted on 2024-08-28

521 Ultra-Long-Term Delivery of Hydrophilic Drugs Using Injectable In Situ Cross-Linked Depots

Lee, S.; Zhao, S.; Jiang, W.; Chen, X.; Zhu, L.; Joseph, J.; Agus, E.; Mary, H. B.; Barooj, S.; Slaughter, K.; Cheung, K.; Luo, J. N.; Shukla, C.; Gao, J.; Lee, D.; Balakrishnan, B.; Jiang, C.; Gorantla, A.; Shah, P.; Woo, S.; Karp, J.; Joshi, N.

10.1101/2023.11.04.565631 — bioengineering — Posted on 2024-08-28

522 The Y951N patient mutation inactivates the intramolecular switch in human mitochondrial DNA POLgamma

Forslund, J. M. E.; Nguyen, T. V. H.; Parkash, V.; Berner, A.; Goffart, S.; Pohjoismaki, J. L. O.; Wanrooij, P. H.; Johansson, E. H.; Wanrooij, S.

10.1101/2024.08.28.610080 — biochemistry — Posted on 2024-08-28

523 Chromosome-level genome assembly and methylome profile enables insights for the conservation of endangered loggerhead sea turtles

Yen, E. C.; Gilbert, J. D.; Balard, A.; Taxonera, A.; Fairweather, K.; Ford, H. L.; Thorburn, D.-M. J.; Rossiter, S. J.; Martin-Duran, J. M.; Eizaguirre, C.

10.1101/2024.08.28.610089 — genomics — Posted on 2024-08-28

524 An accessible digital imaging workflow for multiplexed quantitative analysis of adult eye phenotypes in Drosophila melanogaster

Pipkin, H. J. J.; Lindsay, H. L.; Smiley, A. T.; Jurmu, J. D.; Arsham, A. M.

10.1101/2024.01.26.577286 — genetics — Posted on 2024-08-28

525 Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023-24

Guinat, C.; Fourtune, L.; Lambert, S.; Martin, E.; Gerbier, G.; Jimenez Pellicer, A.; Guerin, J.-L.; Vergne, T.

10.1101/2024.08.28.609837 — ecology — Posted on 2024-08-28

526 Dachsous and Fat coordinately repress the Dachs-Dlish-Approximated complex to control growth

Matakatsu, H.; Fehon, R. G.

10.1101/2024.06.18.599638 — developmental biology — Posted on 2024-08-28

527 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.

Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.

10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-28

528 AutoMorFi: Automated Whole-image Morphometry in Fiji/ImageJ for Diverse Analyses and Discoveries

Bouadi, O.; Yao, C.; Zeng, J.; Beason, D.; Inda, N.; Malone, Z.; Yoshihara, J.; Manjally, A. V.; Johnson, C.; Cherry, J.; Chen, C.-Y.; Huang, T.-C.; Popovic, B.; Henley, M.; Liu, G.; Kharitonova, E. K.; Zeldich, E.; Aichelman, H.; Davies, S. W.; Walentek, P.; Tian, Y.; Man, H.; Ozsen, E.; Harder, K.; Gilmore, T. D.; Pitt, D.; Tay, T. L.

10.1101/2024.07.26.605357 — cell biology — Posted on 2024-08-28

529 PTEN Regulates Myofibroblast Activation in Valvular Interstitial Cells based on Subcellular Localization

Batan, D.; Tseropoulos, G.; Bishop, C.; Kirkpatrick, B. E.; Bera, K.; Khang, A.; Weiser-Evans, M. C.; Anseth, K. S.

10.1101/2024.06.30.601424 — cell biology — Posted on 2024-08-28

530 Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite

Singh, P.; Serizay, J.; Couble, J.; Cabahug, M. D.; Rosa, C.; Chen, P.; Scherf, A.; Koszul, R.; Baumgarten, S.; Bryant, J. M.

10.1101/2024.08.28.610079 — molecular biology — Posted on 2024-08-28

531 Characterization of a High-Affinity Copper Transporter in the White-Nose Syndrome Causing Fungal Pathogen Pseudogym-noascus destructans

Friudenberg, A. D.; Anne, S.; Peterson, R. L.

10.1101/2024.08.28.610057 — microbiology — Posted on 2024-08-28

532 Gain-of-function study reveals the pleiotropic roles of serine protease HtrA in Borrelia burgdorferi

Zhang, K.; Sze, C. W.; Zhao, H.; Liu, J.; Li, C.

10.1101/2024.08.28.610130 — microbiology — Posted on 2024-08-28

533 Identification of a new ORF3a-E fusion subgenomic RNA of SARS-CoV-2 and its biological features in the infection process

Zhang, Y.; Zheng, H.; Li, J.; Zhang, X.; Zhang, X.; Li, J.; Li, H.; Zhao, X.; Zhang, Z.; Li, Y.; Chen, k.; Peng, S.; Zhang, Y.; Shi, H.; Liu, L.

10.1101/2024.08.28.610093 — microbiology — Posted on 2024-08-28

534 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences

Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.

10.1101/2024.03.05.583455 — microbiology — Posted on 2024-08-28

535 Renal outcomes of combination therapy with sodium-glucose cotransporter 2 inhibitors plus renin-angiotensin system blockers in patients with type 2 diabetes mellitus: A population-based cohort study

Tsai, M.-H.; Chen, M.-c.; Huang, Y.-C.; Chang, W.-S.; Hsiao, K.-Y.; Liou, H.-H.; Fang, Y.-W.

10.1101/2024.08.28.610101 — pharmacology and toxicology — Posted on 2024-08-28

536 Sex specific knee joint soft tissue mineralization with Fibrillin-1 mutation in male Tight Skin mice.

Keenan, C.; Wang, X.; Dikmen, T.; Wen, Y.; Ramos-Mucci, L.; Shorter, E.; Abraham, D.; Bou-Gharios, G.; Poulet, B.

10.1101/2024.08.28.610095 — pathology — Posted on 2024-08-28

537 Inhibition of IAPs induces programmed cell death and inflammatory signaling in patient-derived metastatic breast cancer organoids

Waechtershaeuser, K. N.; Schneider, J. V.; Gessner, A.; Andrieux, G.; Kur, I.; Duschek, N.; Weigert, A.; Boerries, M.; Rieger, M. A.; Stelzer, E. H. K.; Pampaloni, F.; van Wijk, S.

10.1101/2024.08.28.610103 — cancer biology — Posted on 2024-08-28

538 RNA order regulates its interactions with zwitterionic lipid bilayers

Singh, A. P.; Prabhu, J.; Vanni, S.

10.1101/2024.08.28.610126 — biophysics — Posted on 2024-08-28

539 Characterizing microbubble-mediated permeabilization in a vessel-on-a-chip model

Meijlink, B.; Collado Lara, G.; Bishard, K.; Conboy, J. P.; Langeveld, S. A. G.; Koenderink, G.; van der Steen, A. F. W.; de Jong, N.; Beekers, I.; Tritsch, S. J.; Kooiman, K.

10.1101/2024.08.28.609836 — bioengineering — Posted on 2024-08-28

540 Structural and kinetic insights into tRNA promoter engagement by yeast general transcription factor TFIIIC

Seifert-Davila, W.; Chaban, A.; Baudin, F.; Girbig, M.; Hauptmann, L.; Hoffmann, T.; Duss, O.; Eustermann, S.; Muller, C. W.

10.1101/2024.08.28.610035 — biochemistry — Posted on 2024-08-28

541 Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses

Park, Y.-J.; Liu, C.; Lee, J.; Brown, J. T.; Ma, C.-B.; Liu, P.; Xiong, Q.; Stewart, C.; Addetia, A.; Craig, C. J.; Tortorici, M. A.; Alshukari, A.; Starr, T.; Yan, H.; Veesler, D.

10.1101/2024.08.28.608351 — biochemistry — Posted on 2024-08-28

542 Decapping activators Edc3 and Scd6 act redundantly with Dhh1 in post-transcriptional repression of starvation-induced pathways

Kumar, R.; Zhang, F.; Niphadkar, S.; Onu, C.; Vijjamarri, A. K.; Greenberg, M. L.; Laxman, S.; Hinnebusch, A. G.

10.1101/2024.08.28.610059 — genetics — Posted on 2024-08-28

543 Genetic suppression interactions are highly conserved across genetic backgrounds

Paltenghi, C.; van Leeuwen, J.

10.1101/2024.08.28.610086 — genetics — Posted on 2024-08-28

544 Polyunsaturated fatty acid-derived lipid mediator networks characterize COVID-19 severity and risk for critical illness

Papadaki, M.; Pavlos, E.; Dubourdeau, M.; Bailif, V.; Badirou, K.; Galani, I.-E.; Papelis, D.; Kamperi, N.; Triantafyllia, V.; Siouti, L.; Salagianni, M.; Manioudaki, M.; Paschalidis, N.; Vatsellas, G.; Koukaki, E.; Rapti, V.; Thanos, D.; Rovina, N.; Poulakou, G.; Cobat, A.; Casanova, J.-L.; Tamvakopoulos, C.; Andreakos, E.

10.1101/2024.08.28.610123 — immunology — Posted on 2024-08-28

545 Engineering Intercellular Communication using M13 Phagemid and CRISPR-based Gene Regulation for Multicellular Computing in Escherichia coli

Kusumawardhani, H.; Zoppi, F.; Avendano, R.; Schaerli, Y.

10.1101/2024.08.28.610043 — synthetic biology — Posted on 2024-08-28

546 High-Throughput Assay for Predicting Diarrhea Risk Using a 2D Human Intestinal Stem Cell-Derived Model

Pike, C. M.; Levi, J. A.; Boone, L. A.; Peddibhotla, S.; Johnson, J.; Zwarycz, B.; Bunger, M. K.; Thelin, W.; Boazak, E. M.

10.1101/2024.08.28.610072 — pharmacology and toxicology — Posted on 2024-08-28

547 Sustained fertility from first-wave follicle oocytes that pause their growth

Soygur, B.; Gaylord, E. A.; Foecke, M. H.; Cincotta, S. A.; Horan, T. J.; Wood, A.; Cohen, P.; Laird, D. J.

10.1101/2024.08.27.609995 — developmental biology — Posted on 2024-08-28

548 Multi-camera Simultaneous Total Internal Reflection and Interference Reflection Microscopy

Spector, J.; Chen, J.; Roll-Mecak, A.

10.1101/2024.08.28.610099 — biophysics — Posted on 2024-08-28

549 Marine spatial planning to enhance coral adaptive potential

10.1101/2024.08.27.609972 — ecology — Posted on 2024-08-28

550 Information-making processes in the speaker's brain drive human conversations forward

Goldstein, A.; Wang, H.; Sheffer, T.; Schain, M.; Zada, Z.; Niekerken, L.; Aubrey, B.; Nastase, S. A.; Gazula, H.; Casto, C.; Doyle, W. K.; Friedman, D.; Devore, S.; Dugan, P.; Hassidim, A.; Brenner, M.; Matias, Y.; Devinsky, O.; Flinker, A.; Hasson, U.

10.1101/2024.08.27.609946 — neuroscience — Posted on 2024-08-28

551 Phase Separation-based Antiviral Decoy Particles as Basis for Programmable Broad-spectrum Therapeutics

Willinger, O.; Granik, N.; Goldberg, S.; Amit, R.

10.1101/2024.08.28.610020 — synthetic biology — Posted on 2024-08-28

552 Loss of the tumor suppressor NUMB drives aggressive bladder cancer through hyperactivation of a RhoA/ROCK/YAP signaling circuitry

Tucci, F. A.; Pennisi, R.; Rigiracciolo, D. C.; Filippone, M. G.; Bonfanti, R.; Romeo, F.; Freddi, S.; Soriani, C.; Rodighiero, S.; Jodice, G.; Sanguedolce, F.; Renne, G.; Fusco, N.; Di Fiore, P. P.; Pruneri, G.; Musi, G.; Vago, G.; Tosoni, D.; Pece, S.

10.1101/2024.08.27.609735 — cancer biology — Posted on 2024-08-28

553 ANLN directly interacts with PCNA to regulate UV induced translesion synthesis

Tong, B.-B.; Cao, Y.-F.; Wen, B.; Fu, T.; Deng, D.-X.; Yang, Q.-H.; Wu, Y.-Q.; Zou, H.-Y.; Liao, L.-D.; Xu, L.-Y.; Li, E.-M.

10.1101/2024.08.27.609892 — cancer biology — Posted on 2024-08-28

554 Thermodynamic versus kinetic basis for the high conformational stability of nanobodies for therapeutic applications

Gomez-Mulas, A.; Salido, E.; Pey, A. L.

10.1101/2024.08.28.609651 — biophysics — Posted on 2024-08-28

555 Focused Ultrasound Impels the Delivery and Penetration of Model Therapeutics into Cerebral Cavernous Malformations

Fisher, D. G.; Hoch, M. R.; Gorick, C. M.; Huchthausen, C.; Breza, V. R.; Sharifi, K. A.; Tvrdik, P.; Miller, G. W.; Price, R. J.

10.1101/2024.08.27.609060 — bioengineering — Posted on 2024-08-28

556 Hemodynamics Affects Factor XI/XII Anticoagulation Efficacy in Patient-Specific Left Atrial Models

Guerrero-Hurtado, M.; Garcia-Villalba, M.; Gonzalo, A.; Duran, E.; Martinez-Legazpi, P.; Kahn, A. M.; Chen, M. Y.; McVeigh, E.; Bermejo, J.; del Alamo, J. C.; Flores, O.

10.1101/2024.08.27.609969 — bioengineering — Posted on 2024-08-28

557 Bronchopulmonary Dysplasia with Pulmonary Hypertension Associates with Loss of Semaphorin Signaling and Functional Decrease in FOXF1 Expression

Shirazi, S. P.; Negretti, N. M.; Jetter, C. S.; Sharkey, A. L.; Garg, S.; Kapp, M. E.; Wilkins, D.; Fortier, G.; Mallapragada, S.; Banovich, N.; Wright, C. V. E.; Frank, D. B.; Kropski, J. A.; Sucre, J. M. S.

10.1101/2024.08.27.609955 — genomics — Posted on 2024-08-28

558 Innovations in Alginate Catabolism Leading to Heterotrophy and Adaptive Evolution of Diatoms

Lim, Z. H.; Zheng, P.; Quek, C.; Nowrousian, M.; Aachmann, F. L.; Jedd, G.

10.1101/2024.08.28.610029 — evolutionary biology — Posted on 2024-08-28

559 Nuclear actin is a critical regulator of Drosophila female germline stem cell maintenance

Green, N. M.; Talbot, D. E.; Tootle, T. L.

10.1101/2024.08.27.609996 — developmental biology — Posted on 2024-08-28

560 Survival of hepatocytes from executioner caspase activation promotes liver regeneration by enhancing JAK/STAT3 activity

Cao, Z.; Qin, L.; Liu, K.; Yao, C.; Li, E.; Hao, X.; Wang, M.; Jiang, B.; Zou, Y.; Hu, H.; Liu, Q.; Shao, C.; Gong, Y.; Sun, G.

10.1101/2024.08.28.610033 — developmental biology — Posted on 2024-08-28

561 A master regulatory loop that activates genes in a temporally coordinated manner in muscle cells of ascidian embryos

Oda, I.; Satou, Y.

10.1101/2024.08.27.610013 — developmental biology — Posted on 2024-08-28

562 Effects of connectivity hyperalignment (CHA) on estimated brain network properties: from coarse-scale to fine-scale

Farahani, F. V.; Nebel, M. B.; Wager, T.; Lindquist, M. A.

10.1101/2024.08.27.609817 — neuroscience — Posted on 2024-08-28

563 Flanker task parameters are related to the strength of association between the ERN and anxiety: a meta-analysis

Buzzell, G. A.; Niu, Y.; Machado, E.; Dickinson, R.; Moser, J. S.; Morales, S.; Troller-Renfree, S. V.

10.1101/2024.08.27.609944 — neuroscience — Posted on 2024-08-28

564 The Human Cerebellum: A Digital Anatomical Atlas at the Level of Individual Folia

Samuelsson, J. G.; Schmahmann, J. D.; Sereno, M.; Rosen, B.; Hamalainen, M. S.

10.1101/2024.08.27.610006 — neuroscience — Posted on 2024-08-28

565 Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution

Fuhrmann, F.; Nebeling, F. C.; Musacchio, F.; Mittag, M.; Poll, S.; Mueller, M.; Ambrad Giovannetti, E.; Maibach, M.; Schaffran, B.; Burnside, E.; Chan, I. C. W.; Lagurin, A.; Reichenbach, N.; Kaushalya, S.; Fried, H.-U.; Linden, S.; Petzold, G.; Tavosanis, G.; Bradke, F.; Fuhrmann, M.

10.1101/2024.08.28.610026 — neuroscience — Posted on 2024-08-28

566 Parallel networks to predict TIMP and protease cell activity of Nucleus Pulposus cells exposed and not exposed to pro-inflammatory cytokines

Baumgartner, L.; Witta, S.; Noailly, J.

10.1101/2024.08.28.609099 — systems biology — Posted on 2024-08-28

567 Reusing excess staple oligonucleotides for economical production of DNA origami

Isinelli, G.; Wintersinger, C.; Lill, P.; Young, O.; Deng, J.; Shih, W.; Zeng, Y.

10.1101/2024.08.27.609958 — synthetic biology — Posted on 2024-08-28

568 Enhancing Photosynthesis under Salt Stress via Directed Evolution in Cyanobacteria

Jiang, Z.; Islam, K. N.; Wolfe, M.; O'Connell, M.; Williams, D.; Florance, A.; Vinyard, D. J.; Zhang, X.; Brenner, M.; Kiss, A. J.; Liu, X.; Wang, X.

10.1101/2024.08.27.610004 — plant biology — Posted on 2024-08-28

569 Prenatal glyphosate exposure disrupts the gut-brain axis across several generations in mice.

Barnett, J. A.; Josephson, J. K.; Haskey, N. A.; Hart, M. M.; Soma, K. K.; Bandy, M. L.; McComb, C. J.; Verdugo, A.; Ghosh, S.; Letef, C.; Copp, A.; Gibon, J.; Ye, J.; Giebelhaus, R. T.; Murch, S. J.; Jung, M. M.; Gibson, D. L.

10.1101/2024.08.27.609990 — pharmacology and toxicology — Posted on 2024-08-28

570 Synergistic Cytotoxicity of Permethrin and N,N-Diethyl-Meta-Toluamide on Sinonasal Epithelial Cells

Lee, J.; Basak, S. K.; Yang, H.-H.; Sullivan, K.; Maxim, T.; Shin, D. S.; Klimas, N.; Srivatsan, E.

10.1101/2024.08.27.610017 — pharmacology and toxicology — Posted on 2024-08-28

571 MYC shapes ER-mitochondria calcium transfer by directly targeting ITPR1: implications for MYC-induced safeguard mechanisms and cancer

Ma, X.; Tsalikis, A.; Vernier, M.; Zhu, K.; El Hassani, J.; Ziegler, D.; Huna, A.; Coquet, C.; Revechon, G.; Margand, C.; Benard, F.; Czarnecka-Herok, J.; Iacono Di Cacito, I.; Koering, C.; Attignon, V.; Carrere, M.; Jollivet, F.; Mollereau, B.; Vanbelle, C.; Gandrillon, O.; Dumont, B.; Delloye-Bourgeois, C.; Hernandez-Vargas, H.; Martin, N.; Bernard, D.

10.1101/2024.08.28.610025 — cancer biology — Posted on 2024-08-28

572 Cancer-associated fibroblasts confer ALK inhibitor resistance in EML4-ALK-driven lung cancer via concurrent integrin and MET signaling

Hu, Q.; Rix, L. L. R.; Desai, B.; Miroshnychenko, D.; Li, X.; Welsh, E. A.; Fang, B.; Wright, G. M.; Chaudhary, N.; Kroeger, J. L.; Doebele, R. C.; Koomen, J. M.; Haura, E. B.; Marusyk, A.; Rix, U.

10.1101/2024.08.27.609975 — cancer biology — Posted on 2024-08-28

573 Break-induced replication drives large-scale genomic amplifications in cancer cells

Abbas, T.; Benamar, M.; Eki, R.; Du, K.-P.

10.1101/2024.08.27.609980 — cancer biology — Posted on 2024-08-28

574 A diverse landscape of FGFR alterations and co-mutations defines novel therapeutic strategies in pediatric low-grade gliomas

Morin, E.; Apfelbaum, A. A.; Sturm, D.; Ayoub, G.; DiGiacomo, J.; Bahadur, S.; Chandarana, B.; Power, P. C.; Cusick, M. M.; Novikov, D.; Jones, R.; Vogelzang, J.; Bossi, C. C.; Malinowski, S.; Jeang, J.; Collins, J.; Oh, S.; Jeon, H.; Cameron, A.; Rechter, P.; Deleon, A.; Murugesan, K.; Montesion, M.; Albacker, L. A.; Ramkissoon, S. H.; van Tilburg, C. M.; Hardin, E. C.; Sievers, P.; Sahm, F.; yeo, K. k.; Rosenberg, T.; Chi, S.; Wright, K.; Hebert, S.; Peck, S.; Picca, A.; Larouche, V.; Renzi, S.; Bale, T.; Smith, A. A.; Touat, M.; Jabado, N.; Fischer, E. S.; Eck, M. J.; Baird, L.; Witt, O.; K

10.1101/2024.08.27.609922 — cancer biology — Posted on 2024-08-28

575 OrthoBrowser: Gene Family Analysis and Visualization

Hartwick, N. T.; Michael, T. P.

10.1101/2024.08.27.609986 — bioinformatics — Posted on 2024-08-28

576 Predicting the bacterial host range of plasmid genomes using the language model-based one-class SVM algorithm

Feng, T.; Chen, X.; Wu, S.; Zhou, H.; Fang, Z.

10.1101/2024.08.27.609848 — bioinformatics — Posted on 2024-08-28

577 Improving N-Glycosylation and Biopharmaceutical Production Predictions Using AutoML-Built Residual Hybrid Models

Seber, P.; Braatz, R. D.

10.1101/2024.08.27.609988 — bioinformatics — Posted on 2024-08-28

578 Peptide therapeutic leads for multi-target inhibition of inflammatory cytokines in Inflammatory Bowel Disease - computational design and in-vitro validation

Tsaban, T.; Kariv-Attias, G.; Khramushin, A.; Gover, O.; Hayouka, Z.; Schueler-Furman, O.; Schwartz, B.

10.1101/2024.08.27.609829 — bioinformatics — Posted on 2024-08-28

579 Ligand Identification using Deep Learning

Karolczak, J.; Przybylowska, A.; Szewczyk, K.; Taisner, W.; Heumann, J. M.; Stowell, M. H. B.; Nowicki, M.; Brzezinski, D.

10.1101/2024.08.27.610022 — bioinformatics — Posted on 2024-08-28

580 Reversal of contractile defects by mediating calcium homeostasis in human mini-heart models of heart failure with preserved ejection fraction (HFpEF) leads to first-in-human gene therapy clinical trial

Costa, K. D.; Wong, A. O. T.; Mak, S. Y.; Roberts, E. G.; Keung, W.; Correia, C.; Walentinsson, A.; Christoffersson, J.; Cheung, A.; Lieu, D. K.; Jennbacken, K.; Wang, Q.-D.; Hajjar, R. J.; Li, R. A.

10.1101/2024.08.27.609034 — bioengineering — Posted on 2024-08-28

581 An automated microfluidic platform for toxicity testing based on Caenorhabditis elegans

Wu, J.; Xi, J.; Zhu, Z.; Peng, Q.; Liu, C.; Yao, J.; Cao, Y.; Luan, Y.

10.1101/2024.08.27.610021 — bioengineering — Posted on 2024-08-28

582 SCRATCH: A programmable, open-hardware, benchtop robot that automatically scratches cultured tissues to investigate cell migration, healing, and tissue sculpting.

Lin, Y.; Silverman-Dutz, A.; Bailey, M.; Cohen, D. J.

10.1101/2024.08.27.609782 — bioengineering — Posted on 2024-08-28

583 Computational modeling of left ventricular flow using PC-CMR-derived four-dimensional wall motion

Peighambari, S. B.; Mukherjee, T.; Mendiola, E. A.; Darwish, A.; Timmins, L. H.; Pettigrew, R. I.; Shah, D. J.; Avazmohammadi, R.

10.1101/2024.08.27.609991 — bioengineering — Posted on 2024-08-28

584 Are super-predators also super-scary? A systematic review and meta-analysis of animal responses to human interactions

Dsouza, S.; Shanker, K.; Thaker, M.

10.1101/2024.08.27.609826 — animal behavior and cognition — Posted on 2024-08-28

585 Complete Chloroplast Genome Sequence and Phylogenetic Analysis of Camellia sinensis sp. Baihaozao

Chen, Z.; College of Agriculture & Biotechnology, Hunan University of Humanities, Science & Technology, ; Zhu, Y.; Demonstration Base for Innovation and Entrepreneurship in the Efficient Utilization of Local Charact, ; He, Z.; Tea Research Institute, Hunan Academy of Agricultural Sciences, ; Li, H.; Taohuayuan Agricultural Development Co., Ltd., ; Huang, J.; Gong, Y.

10.1101/2024.08.27.609997 — genomics — Posted on 2024-08-28

586 Association Between Relational Mobility and DNA Methylation in Oxytocin Receptor Gene: A Social Epigenetic Study

Li, S.; Yamada, J.; Ishihara, T.; Nishina, K.; Nishitani, S.; Sasaki, T.; Matsuda, T.; Inoue-Murayama, M.; Takagishi, H.

10.1101/2024.08.27.609977 — genetics — Posted on 2024-08-28

587 The city and forest bird flock together in a common garden: genetic and environmental effects drive urban phenotypic divergence

Thompson, M. J.; REALE, D.; Chenet, B.; Delaitre, S.; Fargevieille, A.; Romans, M.; Caro, S. P.; Charmantier, A.

10.1101/2024.08.27.609854 — evolutionary biology — Posted on 2024-08-28

588 Solving the SLoSS debate: Scale-dependent effects of habitat fragmentation on biodiversity loss

de Jager, M.; Pos, E.

10.1101/2024.08.27.609888 — ecology — Posted on 2024-08-28

589 Cold and lonely: low-abundance microbiota and no core microbiome across a broad geographic sampling of a mosquito species in Greenland

Rojas-Guerrero, D.; Kolasa, M.; Buczek, M.; Prus-Frankowska, M.; Nowak, K. H.; Roslin, T.; Lukasik, P.

10.1101/2024.08.27.609970 — ecology — Posted on 2024-08-28

590 Allogenic platelet-rich plasma and platelet-rich plasma extracellular vesicles alter the proteome of tenocytes in an in vitro equine model of tendon inflammation: A pilot study

Clarke, E.; Jensen, A.; Gillen, A.; Bardell, D.; Senior, M.; Anderson, J. R.; Peffers, M. J.

10.1101/2024.08.27.609926 — molecular biology — Posted on 2024-08-28

591 Recapitulation of clinical features in a patient-derived xenograft mouse model of VEXAS Syndrome

Arede, L.; Coutinho, R.; Duarte, T. L.; Lopes, M.; Simoes, R.; Silva, S.; Baptista, P.; Lopes, J. M.; Faria, R.; Duarte, D.

10.1101/2024.08.27.609907 — immunology — Posted on 2024-08-28

592 EEG During Dynamic Facial Emotion Processing Reveals Neural Activity Patterns Associated with Autistic Traits in Children

Hill, A. T.; Ford, T. C.; Bailey, N. W.; Lum, J. A. G.; Bigelow, F. J.; Oberman, L. M.; Enticott, P. G.

10.1101/2024.08.27.609816 — neuroscience — Posted on 2024-08-28

593 The ERGtools2 package: A Toolset for Processing and Analysing Visual Electrophysiology Data

Lindner, M.

10.1101/2024.08.27.609856 — neuroscience — Posted on 2024-08-28

594 Auditory perception and neural representation of temporal fine structure are impaired by age but not by cochlear synaptopathy

Steenken, F.; Beutelmann, R.; Oetjen, H.; Koeppl, C.; Klump, G. M.

10.1101/2024.08.27.609839 — neuroscience — Posted on 2024-08-28

595 A novel baseline-effect shift tracking model for more sensitive detection of differences in the effects of closely related dopamine transporter inhibitor/ sigma receptor antagonist drug combinations on psychostimulant use.

Paul, R.; Gandhi, R. M.; Job, M. O.

10.1101/2024.08.27.609852 — neuroscience — Posted on 2024-08-28

596 Cell type-specific impact of aging and Alzheimer disease on hippocampal CA1 perforant path input

Santoro, B.; Srinivas, K. V.; Reyes, I.; Tian, C.; Masurkar, A. V.

10.1101/2024.08.27.609952 — neuroscience — Posted on 2024-08-28

597 Neuronal heterogeneity in the medial septum and diagonal band of Broca: classes and continua

Kuhn, F.; Mocellin, P.; Pupe, S.; Cembrowski, M. S.; Remy, S.

10.1101/2024.08.27.609593 — neuroscience — Posted on 2024-08-28

598 Differential encoding of mammalian proprioception by voltage-gated sodium channels

Espino, C. M.; Nagaraja, C.; Ortiz, S.; Dayton, J. R.; Murali, A. R.; Ma, Y.; Mann, E. L.; Garlapalli, S.; Wohlgemuth, R. P.; Brashear, S. E.; Smith, L. R.; Wilkinson, K. A.; Griffith, T. N.

10.1101/2024.08.27.609982 — neuroscience — Posted on 2024-08-28

599 Non-spatial hippocampal behavioral timescale synaptic plasticity during working memory is gated by entorhinal inputs

Dorian, C. C.; Taxidis, J.; Golshani, P.

10.1101/2024.08.27.609983 — neuroscience — Posted on 2024-08-28

600 Missing links connect the phylogeographic structure of endangered red pandas, remaining as one species -- Ailurus fulgens, and expediting conservation

Dueck, L. A.; Uluer, D. A.

10.1101/2024.08.27.609966 — zoology — Posted on 2024-08-28

601 Time-resolved, integrated multi-omic analysis reveals central role of amino acid pathways for defense responses in Arabidopsis thaliana

Joller, C.; Schlaeppi, K.; Sasse, J.

10.1101/2024.08.27.609849 — plant biology — Posted on 2024-08-28

602 OsWHY1/OsTRXz/OsMORFs complex is essential for RNA modification and early chloroplast development in rice

Zheng, X.; Lu, Q.; Luo, Y.; Xu, J.; Wang, W.; Tan, M.; Liao, D.; Hong, W.; Chen, S.; Lin, C.; Wang, X.; Fan, C.; Habiba, ; Wang, X.; Li, Y.; Zhang, Y.; Lin, W.; Miao, Y.

10.1101/2024.08.28.610128 — plant biology — Posted on 2024-08-28

603 Anesthetic-like effects of ketamine in C. elegans

Seppala, K.; Reigada, I.; Matilainen, O.; Rantamaki, T.; Hanski, L.

10.1101/2024.08.28.610063 — pharmacology and toxicology — Posted on 2024-08-28

604 Global Scientific Trends in Organoids from 2004 to 2023: A Data Bibliometric and Visualized Analysis

Zhao, M.; Kuang, L.; Guo, H.; Cao, X.; Dai, J.; Wang, Y.; Wang, Z.; Peng, C.

10.1101/2024.08.28.610094 — cancer biology — Posted on 2024-08-28

605 Glioblastoma stem cells show transcriptionally correlated spatial organization

Ayyadhury, S.; Sachamitr, P.; Kushida, M.; Park, N.; Coutinho, F.; Whitley, O.; Prinos, P.; Arrowsmith, C.; Dirks, P. B.; Pugh, T.; Bader, G.

10.1101/2024.08.27.609918 — cancer biology — Posted on 2024-08-28

606 Machine Learning Uncovers Vascular Endothelial Cell Identity Genes by Expression Regulation Features in Single Cells

Arulsamy, K.; Xia, B.; Chen, H.; Zhang, L.; Chen, K.

10.1101/2024.08.27.609808 — bioinformatics — Posted on 2024-08-28

607 A Bioinert Hydrogel Framework for Precision 3D Cell Cultures: Advancing Automated High-Content and High-Throughput Drug Screening

Jeon, H.; Zanon, T. T. M.; Carpenter, J.; Ilias, A.; Colon, Y.; Wang, Y.

10.1101/2024.08.27.609940 — bioengineering — Posted on 2024-08-28

608 Route Learning and Transport of Resources during Colony Relocation in Australian Desert Ants

Deeti, S.; Cheng, K.

10.1101/2024.08.27.609847 — animal behavior and cognition — Posted on 2024-08-28

609 Is variation in female aggressiveness across Drosophila species associated with reproductive potential?

Bath, E.; Gleason, J. M.

10.1101/2024.08.27.609931 — animal behavior and cognition — Posted on 2024-08-28

610 Y chromosome STR variation reveals traditional occupation based population structure in India

Sequeira, J. J.; Chaitra, M.; Rai N R, A.; Sudeepthi, M.; Shalini, R.; Mustak, M. S.; Khanna, J.; Sharma, S.; Chilukuri, R. V. E.; Driem, G. v.; Shrivastava, P.

10.1101/2024.08.28.610024 — genetics — Posted on 2024-08-28

611 Evidence for recruitment-mediated decline in an Eastern box turtle (Terrapene carolina carolina) population based on a 30-year capture-recapture data set from Maryland

Royle, A.; Quinlan, M. M.; Swarth, C. W.

10.1101/2024.08.28.610102 — ecology — Posted on 2024-08-28

612 Yes, they're all individuals: Hierarchical models for repeat survey data improve estimates of tree growth and size

O'Brien, T.; Warton, D.; Falster, D. S.

10.1101/2024.08.27.609830 — ecology — Posted on 2024-08-28

613 The PIDDosome controls cardiomyocyte polyploidization during postnatal heart development

Leone, M.; Eichin, F.; Kinz, N.; Obwegs, D.; Sladky, V. C.; Rizzotto, D.; Manzl, C.; Moos, K.; Savko, C.; Jacotot, E. D.; Sussman, M.; Boerries, M.; Villunger, A.

10.1101/2024.08.27.609375 — developmental biology — Posted on 2024-08-28

614 Horizontal gene transfer can reshape bacterial warfare

Granato, E. T.; Palmer, J. D.; Kirk, C.; Sharp, C.; Shillcock, G.; Foster, K. R.

10.1101/2024.08.28.610076 — microbiology — Posted on 2024-08-28

615 Circulation of West Nile Virus and Usutu Virus in Birds in Germany, 2021 and 2022.

Schopf, F.; Sadeghi, B.; Bergmann, F.; Fischer, D.; Rahner, R.; Mueller, K.; Guenther, A.; Globig, A.; Keller, M.; Schwehn, R.; Guddorf, V.; Reuschel, M.; Fischer, L.; Krone, O.; Rinder, M.; Schuette, K.; Schmidt, V.; Heenemann, K.; Schwarzer, A.; Fast, C.; Sauter-Louis, C.; Staubach, C.; Luehken, R.; Schmidt-Chanasit, J.; Brandes, F.; Lierz, M.; Korbel, R.; Vahlenkamp, T. W.; Groschup, M. H.; Ziegler, U.

10.1101/2024.08.28.610071 — microbiology — Posted on 2024-08-28

616 WITHDRAWN: Geometrical determinant of nonlinear synaptic integration in human cortical pyramidal neurons

Yoon, J.

10.1101/2024.07.14.601255 — neuroscience — Posted on 2024-08-28

617 ProtAlign-ARG: Antibiotic Resistance Gene Characterization Integrating Protein Language Models and Alignment-Based Scoring

Ahmed, S.; Emon, M. I.; Moumi, N. A.; Huang, L.; Zhou, D.; Vikesland, P.; Pruden, A.; ZHANG, L.

10.1101/2024.03.20.585944 — bioinformatics — Posted on 2024-08-28

618 Assessing models' sensitivity to the effects of forest management and climate change on carbon and water fluxes in European beech forests

Saponaro, V.; De Caceres, M.; Dalmonech, D.; D'Andrea, E.; Vangi, E.; Collalti, A.

10.1101/2024.08.20.608827 — ecology — Posted on 2024-08-28

619 Pangenomes reveal genomic signatures of microbial adaptation to experimental soil warming

Choudoir, M. J.; Narayanan, A.; Rodriguez-Ramos, D.; Simoes, R.; Efroni, A.; Sondrini, A.; DeAngelis, K. M.

10.1101/2023.03.16.532972 — microbiology — Posted on 2024-08-28

620 Fusobacterium sphaericum sp. nov., isolated from a human colon tumor, adheres to colonic epithelial cells and induces IL-8 secretion

Zepeda-Rivera, M. A.; Eisele, Y.; Baryiames, A.; Wu, H.; Mengoni, C.; Piccinno, G.; McMahon, E.; LaCourse, K. D.; Jones, D. S.; Hauner, H.; Minot, S. S.; Segata, N.; Dewhirst, F. E.; Johnston, C. D.; Bullman, S.

10.1101/2023.06.16.545380 — microbiology — Posted on 2024-08-28

621 kcnb1 loss-of-function in zebrafish causes neurodevelopmental and epileptic disorders associated with GABA dysregulation

Robichon, L.; Bar, C.; Marian, A.; Lehmann, L.; Renault, S.; Kabashi, E.; Ciura, S.; Nabbout, R.

10.1101/2024.07.03.601913 — neuroscience — Posted on 2024-08-28

622 Astrocytic LRRK2 Controls Synaptic Connectivity via Regulation of ERM Phosphorylation

Wang, S.; Baumert, R.; Sejourne, G.; Sivadasan Bindu, D.; Dimond, K.; Sakers, K.; Vazquez, L.; Moore, J. L.; Tan, C. X.; Takano, T.; Rodriguez Salazar, M. P.; Soderling, S. H.; La Spada, A. R.; Eroglu, C.

10.1101/2023.04.09.536178 — neuroscience — Posted on 2024-08-28

623 Visuomotor prediction during action planning in the human frontoparietal cortex and cerebellum

Quirmbach, F.; Limanowski, J.

10.1101/2023.07.20.549926 — neuroscience — Posted on 2024-08-28

624 Make or break: The influence of expected challenges and rewards on the motivation and experience associated with cognitive effort exertion

Zhang, Y.; Leng, X.; Shenhav, A.

10.1101/2023.12.05.570154 — neuroscience — Posted on 2024-08-28

625 The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion.

Mallimadugula, U. L.; Cruz, M. A.; Vithani, N.; Zimmerman, M. I.; Bowman, G. R.

10.1101/2024.08.22.609218 — biophysics — Posted on 2024-08-28

626 Imputation of cancer proteomics data with a deep model that learns from many datasets

Harris, L.; Noble, W. S.

10.1101/2024.08.26.609780 — bioinformatics — Posted on 2024-08-28

627 Exploring SNP Filtering Strategies: The Influence of Strict vs Soft Core

Taouk, M. L.; Featherstone, L. A.; Taiaroa, G.; Ingle, D. J.; Stinear, T. P.; Wick, R. R.

10.1101/2024.08.26.609800 — genomics — Posted on 2024-08-28

628 Moesin controls cell-cell fusion and osteoclast function

Dufrancais, O.; Verdys, P.; Plozza, M.; Metais, A.; Juzans, M.; Sanchez, T.; Bergert, M.; Halper, J.; Panebianco, C. J.; Mascarau, R.; Gence, R.; Arnaud, G.; Ben Neji, M.; Maridonneau-Parini, I.; Le Cabec, V.; Boerckel, J. D.; Pavlos, N.; Diz-Munoz, A.; Lagarrigue, F.; Blin-Wakkach, C.; Carreno, S.; Poincloux, R.; Burkhardt, J. K.; Raynaud-Messina, B.; Verollet, C.

10.1101/2024.05.13.593799 — cell biology — Posted on 2024-08-28

629 Antibiotic-resistant bacteria in agricultural soil appraised against non-agricultural soil: case in one of the most agriculturally-active settings in West Cameroon

Kamgaing Nkamguia, L. K.; Youte, O. D.; Tamatcho Kweyang, B. P.; Kougang, E. G.; Well a Well a Koul, P. B.; Nana Feukeu, A.; Domngang Noche, C.; Fotsing Kwetche, P. R.

10.1101/2024.08.27.609998 — microbiology — Posted on 2024-08-28

630 Cytosolic sodium accumulation is a common danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation

Mangan, M. S. J.; Akbal, A.; Rivara, S.; Schroeder, A.; Horvath, G. L.; Walch, P.; Hegermann, J.; Kaiser, R.; Duthie, F.; Selkrig, J.; Jantsch, J.; Gerhard, R.; Wachten, D.; Latz, E.

10.1101/2024.03.26.586774 — immunology — Posted on 2024-08-28

631 Transcriptome-wide identification of 5-methylcytosine by deaminase and reader protein-assisted sequencing

Zhou, J.; Zhao, D.; Li, J.; Kong, D.; Li, X.; Zhang, R.; Liang, Y.; Gao, X.; Qian, Y.; Wang, D.; Chen, J.; Lai, L.; Han, Y.; Li, Z.

10.1101/2024.04.17.589933 — biochemistry — Posted on 2024-08-28

632 Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery

Adriaenssens, E.; Schaar, S.; Cooke, A. S. I.; Stuke, J. F. M.; Sawa-Makarska, J.; Nguyen, T. N.; Ren, X.; Schuschnig, M.; Romanov, J.; Khuu, G.; Lazarou, M.; Hummer, G.; Hurley, J. H.; Martens, S.

10.1101/2024.08.28.609967 — cell biology — Posted on 2024-08-28

633 High-throughput Image-based Clustering of CAR-T/Tumor Cocultures for Rapid and Facile Hit Identification

Xu, Z.; Liu, X.; Madden-Hennessey, K.; Urbani, J.; Nikkhoi, S. K.; Ramasubramanian, A.; G. Venugopal, K.; Zhao, Q.; L. Smith, E.; Fu, Y.

10.1101/2024.08.28.609577 — cell biology — Posted on 2024-08-28

634 Feedback regulation by the RhoA-specific GEF ARHGEF17 regulates actomyosin network disassembly

Rao, V.; Gradel, B.; Hinderling, L.; Unen, J. v.; Pertz, O.

10.1101/2024.08.28.610052 — cell biology — Posted on 2024-08-28

635 Bradyrhizobium hardenbergiae sp. nov., isolated from Hardenbergia violacea in Australia, represents a novel basal lineage of the B. elkanii supergroup

Lafay, B.; Coquery, E.; Oger, P. M.

10.1101/2024.08.26.609660 — microbiology — Posted on 2024-08-28

636 Activational and organizational effects of sex hormones on hippocampal inhibitory neurons

Hernandez-Vivanco, A.; de la Vega Ruiz, R.; Montes-Mellado, A.; Azcoitia, I.; Mendez, P.

10.1101/2024.01.20.576232 — neuroscience — Posted on 2024-08-28

637 Simulating growth of TDP-43 cytosolic inclusion bodies in neurons

Kuznetsov, A. V.

10.1101/2023.11.28.569118 — biophysics — Posted on 2024-08-28

638 Tree reconstruction guarantees from CRISPR-Cas9 lineage tracing data using Neighbor-Joining

Prillo, S.; An, K.; Wu, W.; Kristanto, I.; Jones, M. G.; Song, Y. S.; Yosef, N.

10.1101/2024.08.27.610007 — bioinformatics — Posted on 2024-08-28

639 Exploration of Natural Products for Targeting IDH1 and IDH2 Mutations in Acute Myeloid Leukemia Through Ligand-Based Pharmacophore Screening and Molecular Dynamic Simulation Approaches

Das, U.; Regati, D. R.; Kumar, J.; Sowdhamini, R.

10.1101/2024.08.27.609840 — bioinformatics — Posted on 2024-08-28

640 Transplantation of bioengineered lung using decellularized mouse lungs and primary human endothelial cells.

Suzuki, T.; Watanabe, T.; Tomiyama, F.; Ito, T.; Okada, Y.

10.1101/2024.08.26.609632 — bioengineering — Posted on 2024-08-28

641 Early founder effects have determined paternal population structure in the Faroe Islands

Mann, A. E.; Magnussen, E.; Tillquist, C. R.

10.1101/2024.08.27.601563 — genetics — Posted on 2024-08-28

642 The evolution of reversible plasticity in stable environments

Walasek, N.; Panchanathan, K.; Frankenhuis, W.

10.1101/2024.08.27.609887 — evolutionary biology — Posted on 2024-08-28

643 PDG-Arena: An ecophysiological model for characterizing tree-tree interactions in heterogeneous and mixed stands

Rouet, C.; Davi, H.; Druel, A.; Fady, B.; Morin, X.

10.1101/2024.02.09.579667 — ecology — Posted on 2024-08-28

644 Pericytes require physiological oxygen tension to maintain phenotypic fidelity.

McErlain, T.; McCulla, E. C.; Glass, M. J.; Ziemer, L. E.; Branco, C. M.; Murgai, M.

10.1101/2024.08.28.606682 — cell biology — Posted on 2024-08-28

645 Single-molecule analysis of protein targeting from the endoplasmic reticulum to lipid droplets

Mizrak, A.; Kaestel-Hansen, J.; Matthias, J.; Harper, J. W.; Hatzakis, N. S.; Walther, T. C.; Farese, R. V.

10.1101/2024.08.27.610018 — cell biology — Posted on 2024-08-28

646 A remarkable degree of conformance between the visual streak of the Mongolian gerbil and the human central retina

Günter, A.; Jarboui, M. A.; Mühlfriedel, R.; Seeliger, M. W.

10.1101/2024.08.28.610039 — cell biology — Posted on 2024-08-28

647 Genome-wide Search for Gene Mutations likely Conferring Insecticide Resistance in the Common Bed Bug, Cimex lectularius

Toga, K.; Kimoto, F.; Fujii, H.; Bono, H.

10.1101/2024.08.27.607709 — genomics — Posted on 2024-08-28

648 Artificial selection for adult predation survival impacts life history and morphology in guppies (Poecilia reticulata)

De Waele, H.; Vega-Trejo, R.; Vila-Pouca, C.; Noordenbos, J.; Phillips, E.; Pollux, B. J. A.; Kotrschal, A.

10.1101/2024.08.27.609842 — evolutionary biology — Posted on 2024-08-28

649 Phylodynamics beyond neutrality: The impact ofincomplete purifying selection on viral phylogeniesand inference

Koelle, K.; Rasmussen, D.

10.1101/2024.08.28.610037 — evolutionary biology — Posted on 2024-08-28

650 High nutritional conditions influence feeding plasticity in Pristionchus pacificus and render worms non-predatory

Piskobulu, V.; Athanasouli, M.; Witte, H.; Feldhaus, C.; Streit, A.; Sommer, R. J.

10.1101/2024.08.27.609904 — evolutionary biology — Posted on 2024-08-28

651 Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

Baek, O.; Muk, T.; Wu, Z.; Ye, Y.; Khakimov, B.; Casano, A. M.; Gangadharan, B.; Bilic, I.; Brunse, A.; Sangild, P. T.; Nguyen, D. N.

10.1101/2023.09.11.557116 — immunology — Posted on 2024-08-28

652 Reconfiguration of Functional Brain Hierarchy in Schizophrenia

Acero, I.; Escrichs, A.; Dagnino, P. C. C.; Sanz Perl, Y.; Kringelbach, M. L.; Uhlhaas, P. J.; Deco, G.

10.1101/2024.08.27.608945 — neuroscience — Posted on 2024-08-28

653 Developmental trajectory of thalamus topography during the late preterm and perinatal period in normal development, after premature birth and in congenital heart defects

Ji, H.; Wu, Z.; Speckert, A.; Tuura, R.; Hagmann, C.; Latal, B.; Knirsch, W.; Jakab, A.

10.1101/2024.08.27.608544 — neuroscience — Posted on 2024-08-28

654 Kynurenine monooxygenase blockade reduces endometriosis-like lesions, improves visceral hyperalgesia, and rescues mice from a negative behavioural phenotype in experimental endometriosis.

Higgins, B.; Simitsidellis, I.; Zheng, X.; Collins, F.; Homer, N.; Denham, S.; Simpson, J.; Millar, M.; Boswell, L.; Lee, H. Y.; Kim, Y. G.; Park, K. H.; Park, L. C.; Sweeney, P. J.; Feraille, G.; Taddei, A.; Chagras, D.; Alvarez, T.; Webster, S. P.; Horne, A. W.; Saunders, P. T.; Mole, D. J.

10.1101/2024.05.13.593856 — pathology — Posted on 2024-08-28

655 Physical constraints and biological regulations underlie universal osmoresponses

Ye, Y.; Wang, Q.; Lin, J.

10.1101/2024.07.02.601668 — biophysics — Posted on 2024-08-28

656 Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP

Yousefpour, P.; J. Zhang, Y.; Maiorino, L.; Melo, M. B.; Arainga Ramirez, M. A.; Kumarapperuma, S. C.; Xiao, P.; Silva, M.; Li, N.; Michaels, K. K.; Georgeson, E.; Eskandarzadeh, S.; Kubitz, M.; Groschel, B.; Qureshi, K.; Fontenot, J.; Hangartner, L.; Nedellec, R.; Love, J. C.; Burton, D. R.; Schief, W. R.; Villinger, F. J.; Irvine, D. J.

10.1101/2024.08.28.608716 — bioengineering — Posted on 2024-08-28

657 A Cryo-to-Liquid Phase Correlative Light Electron Microscopy Workflow for the Visualization of Biological Processes in Graphene Liquid Cells

Rutten, L.; Joosten, B.; Schaart, J. M.; Beer, M. d.; Roverts, R.; Graber, S.; Jahnen-Dechent, W.; Akiva, A.; Macias-Sanchez, E.; Sommerdijk, N.

10.1101/2023.05.08.539575 — biochemistry — Posted on 2024-08-28

658 Training Harbor Seals to Participate in Vocal Learning Experiments in a Zoo

Duengen, D.; Ravignani, A.

10.1101/2024.08.27.609954 — animal behavior and cognition — Posted on 2024-08-28

659 An experimental validation test of ecological coexistence theory to forecast extinction under rising temperatures.

Terry, C.

10.1101/2024.02.22.581553 — ecology — Posted on 2024-08-28

660 InsectChange: Comment

Gaume, L.; Desquilbet, M.

10.1101/2023.06.17.545310 — ecology — Posted on 2024-08-28

661 Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines

Wolff, C.; Neuenschwander, M.; Beese, C. J.; Sitani, D.; Ramos, M. C.; Srovnalova, A.; Varela, M. J.; Polishchuk, P.; Skopelitou, K. E.; Skuta, C.; Stechmann, B.; Brea, J.; Clausen, M. H.; Dzubak, P.; Fernandez-Godino, R.; Genilloud, O.; Hajduch, M.; Loza, M. I.; Lehmann, M.; von Kries, J. P.; Sun, H.; Schmied, C.

10.1101/2024.08.27.609964 — cell biology — Posted on 2024-08-28

662 Versatile gamma-tubulin complexes contribute to the dynamic organization of MTOCs during Drosophila spermatogenesis

Alzyoud, E.; Nemeth, D.; Vedelek, V.; Szögi, T.; Toth, V. P.; Krecsmarik, M.; Abraham, E.; Lipinszki, Z.; Sinka, R.

10.1101/2024.03.20.585862 — cell biology — Posted on 2024-08-28

663 Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in MPS VII

Mandal, N.; Das, A.; Datta, R.

10.1101/2024.08.23.609363 — cell biology — Posted on 2024-08-28

664 Cyclin CLB2 mRNA localization and protein synthesis link cell cycle progression to bud growth

Maekiniemi, A.; Savakis, P.; Snoep, J. L.; Seiler, M.; van Rossum, K.; van Niekerk, D. D.; Zarnack, K.; Singer, R. H.; Tutucci, E.

10.1101/2022.03.01.481833 — molecular biology — Posted on 2024-08-28

665 Telomerase RNA component knockout exacerbates S. aureus pneumonia by extensive inflammation and dysfunction of T cells

Reisser, Y.; Hornung, F.; Haeder, A.; Lauf, T.; Nietzsche, S.; Löffler, B.; Deinhardt-Emmer, S.

10.1101/2024.06.19.599722 — microbiology — Posted on 2024-08-28

666 BRAIN-METASTATIC MELANOMA MODELS UNCOVER IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY

Daugherty-Lopes, A.; Perez-Guijarro, E.; Gopalan, V.; Rappaport, J.; Chen, Q.; Huang, A.; Lam, K. C.; Chin, S.; Ebersole, J.; Wu, E.; Needle, G. A.; Church, I.; Kyriakopoulos, G.; Xie, S.; Zaho, Y.; Gruen, C.; Sassano, A.; Araya, R. E.; Thorkelsson, A.; Smith, C.; Lee, M. P.; Hannenhalli, S.; Day, C.-P.; Merlino, G.; Goldszmid, R. S.

10.1101/2024.08.26.609785 — immunology — Posted on 2024-08-28

667 Movie reconstruction from mouse visual cortex activity

Bauer, J.; Margrie, T. W.; Clopath, C.

10.1101/2024.06.19.599691 — neuroscience — Posted on 2024-08-28

668 Mu opioid receptors gate the locus coeruleus pain generator

Norris, M. R.; Kuo, C.-C.; Dunn, S. S.; Kim, J. R.; Becker, L. J.; Borges, G.; Thang, L. V.; Parker, K. E.; McCall, J. G.

10.1101/2023.10.20.562785 — neuroscience — Posted on 2024-08-28

669 Conditional Knockout of Striatal Gnal Produces Dystonia-like Motor Phenotypes

Chambers, N. E.; Hall, D.; Barsoum, S.; Miller, E.; Curry, T.; Kaplan, M.; Garan, S.; Gallardo, I.; Staab, R.; Nabert, D.; Hutchison, K.; Millett, M.; Moehle, M. S.

10.1101/2024.08.26.609754 — neuroscience — Posted on 2024-08-28

670 Neural circuit-selective, multiplexed pharmacological targeting of prefrontal cortex-projecting locus coeruleus neurons drives antinociception

Kuo, C.-C.; McCall, J. G.

10.1101/2024.06.08.598059 — neuroscience — Posted on 2024-08-28

671 Machine learning and data-driven inverse modeling of metabolomics unveil key process of active aging

Li, J.; brenner, m.; pierides, i.; wessner, b.; franzke, b.; strasser, e. m.; Waldherr, S.; wagner, k. h.; Weckwerth, W.

10.1101/2024.08.27.609825 — systems biology — Posted on 2024-08-28

672 Fetal liver neutrophils are responsible for the postnatal neutrophil surge

Ishiwata, R.; Morimoto, Y.

10.1101/2024.08.26.609612 — physiology — Posted on 2024-08-28

673 Causal, Predictive Or Observational? Different Understandings Of Key Event Relationships For Adverse Outcome Pathways

Zhou, Z.; Pennings, J. L. A.; Sahlin, U.

10.1101/2024.06.25.599864 — pharmacology and toxicology — Posted on 2024-08-28

674 Modulation of blood-tumor barrier transcriptional programs improves intra-tumoral drug delivery and potentiates chemotherapy in GBM

Macias, J. L. J.; Vaughn-Beaucaire, P.; Bharati, A.; Xu, Z.; Forrest, M.; Hong, J.; Sun, M.; Schmidt, A.; Clark, J.; Hawkins, W.; Mercado, N.; Real, J.; Huntington, K.; Zdioruk, M.; Nowicki, M. O.; Cho, C.-F.; Wu, B.; Li, W.; Logan, T.; Manz, K. E.; Pennell, K. D.; Fedeles, B. I.; Brodsky, A. S.; Lawler, S. E.

10.1101/2024.08.26.609797 — cancer biology — Posted on 2024-08-28

675 Dynamic positioning of a TFIIE-related winged-helix domain in RNA polymerase elongation complex III underpins its multi-functionality

Wu, J.-S.; Lin, Y.-C.; Wei, Y.-Y.; Lin, H.-H.; Liu, Y.-C.; Chang, J.-W.; Tu, I.-P.; Chen, H.-T.; Chang, W.-H.

10.1101/2024.08.27.609947 — biophysics — Posted on 2024-08-28

676 Multiple factors regulate i-motif and G-quadruplex structures in vitro: analysis of repeated and non-repeated polyG/polyC clusters by circular dichroism

Diggins, L.; Ross, D.; Bhanot, S.; Corallo, R.; Daley, R.; Patel, K.; Lewis, O.; Donahue, S.; Thaddeus, J.; Hiers, L.; Syed, C.; Eagerton, D.; Mohanty, B. K.

10.1101/2024.08.26.609788 — biophysics — Posted on 2024-08-28

677 Evaluation of Iron Oxide Nanoparticles for Lymph Node Detection with Magnetomotive Ultrasound- A Pilot Study in Rats

Axelsson, U.; Backstrom, S.; Mousavi, A.; Persson, L.

10.1101/2024.08.28.610049 — biophysics — Posted on 2024-08-28

678 Imputation of cancer proteomics data with a deep model that learns from many datasets

Noble, W. S.; Harris, L.

10.1101/2024.08.26.609780 — bioinformatics — Posted on 2024-08-28

679 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle

Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.

10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-28

680 A multiomic atlas of human early skeletal development

To, K.; Fei, L.; Pett, J. P.; Roberts, K.; Polanski, K.; Li, T.; Yayon, N.; He, P.; Xu, C.; Cranley, J.; Li, R.; Kanemaru, K.; Huang, N.; Megas, S.; Richardson, L.; Kapuge, R.; Perera, S.; Tuck, E.; Wilbrey-Clark, A.; Mulas, I.; Memi, F.; Cakir, B.; Predeus, A. V.; Horsfall, D.; Murray, S.; Prete, M.; Mazin, P.; He, X.; Meyer, K. B.; Haniffa, M.; Barker, R. A.; Bayraktar, O.; Buckley, C. D.; Teichmann, S. A.

10.1101/2024.07.10.602965 — developmental biology — Posted on 2024-08-28

681 The VVBlue assay: a plate-readable, dye exclusion-based cell viability assay for the toxicological testing of chemicals

Vitipon, M.; Akingbagbohun, E.; Rabilloud, T.

10.1101/2024.08.27.609841 — cell biology — Posted on 2024-08-28

682 The cytokinetic midbody mediates asymmetric fate specification at mitotic exit during neural stem cell division

LaFoya, B.; Penkert, R. R.; Prehoda, K.

10.1101/2024.08.27.609974 — cell biology — Posted on 2024-08-28

683 Membrane potential modulates ERK activity and cell proliferation

Sasaki, M.; Nakahara, M.; Hashiguchi, T.; Ono, F.

10.1101/2024.08.27.610010 — cell biology — Posted on 2024-08-28

684 LncRNA-536 and RNA Binding Protein RBM25 Interactions in Pulmonary Arterial Hypertension

Mahajan, A.; Kumar, A.; Chen, L.; Dhillon, N. K.

10.1101/2024.08.27.610011 — cell biology — Posted on 2024-08-28

685 Diseased skin dermal proteomic profiles reflect shared extracellular matrix dysregulation patterns

Martins, L.; Malta, M. D.; Chaves, S.; Osorio, H.; Guttmann-Gruber, C.; Kocher, T.; Marques, A. P.

10.1101/2024.08.27.609987 — cell biology — Posted on 2024-08-28

686 Running on empty: Mitochondria without mtDNA exhibit differential motility and connectivity

Chustecki, J. M.; Schneider, A. Q.; Faber, M. H.; Christensen, A. C.

10.1101/2024.08.27.609985 — cell biology — Posted on 2024-08-28

687 Inpp5e is a Critical Regulator of Protein Transport to Photoreceptor Outer Segments

Gupta, M.; Lewis, T. R.; Stuck, M. W.; Spencer, W. J.; Klementieva, N. V.; Arshavsky, V. Y.; Pazour, G. J.

10.1101/2024.08.27.609873 — cell biology — Posted on 2024-08-28

688 Wound-initiated hair regeneration by adhesive and shrinkable materials

Kokabu, S.; Tsuji, K.; Washio, A.; Murata, K.; Nakatomi, M.; Ono, Y.; Kaminuma, O.; Matsubara, T.

10.1101/2024.08.27.610012 — cell biology — Posted on 2024-08-28

689 HIRA-dependent provision of histone H3.3 in active chromatin ensures genome compartmentalisation

Karagyozova, T.; Gatto, A.; Forest, A.; Quivy, J.-P.; Marti-Renom, M. A.; Mirny, L.; Almouzni, G.

10.1101/2024.08.27.609896 — cell biology — Posted on 2024-08-28

690 NEMF-mediated CAT-tailing defines distinct branches of translocation-associated quality control

Ennis, A.; Wang, L.; Wang, X.; Yu, C.; Saidi, L.; Xu, Y.; Yun, S.; Huang, L.; Ye, Y.

10.1101/2024.08.27.610005 — cell biology — Posted on 2024-08-28

691 Vibrio alginolyticus is the pathogen of 'Baotou disease causing serious damage to Gracilariopsis lemaneiformis cultivation in China

Pang, T.; Wang, F.; Guo, Q.; Zhang, M.; Sun, Y.; Liu, J.

10.1101/2024.08.27.609959 — microbiology — Posted on 2024-08-28

692 Modeling Decision-Making Under Uncertainty with Qualitative Outcomes

Korem, N.; Duek, O.; Jia, R.; Wertheimer, E.; Metviner, S.; Grubb, M.; Levy, I.

10.1101/2024.08.27.609831 — neuroscience — Posted on 2024-08-28

693 Non-guided, Mobile, CBT-I-based Sleep Training in War-torn Ukraine: A Feasibility Study

Kurapov, A.; Blechert, J.; Hinterberger, A.; Topalidis, P.; Schabus, M.

10.1101/2024.08.26.609792 — neuroscience — Posted on 2024-08-28

694 Near-infrared MINFLUX imaging enabled by suppression of fluorophore blinking

Srambickal, C. V.; Esmaeeli, H.; Piguet, J.; Reinkensmeier, L.; Siegmund, R.; Bates, M.; Egner, A.; Widengren, J.

10.1101/2024.08.27.609859 — biophysics — Posted on 2024-08-28

695 The Effect of THz Electromagnetic Field on the Conductance of Potassium and Sodium Channels

Song, Z.; Xue, L.; Ouyang, Q.; Song, C.

10.1101/2024.08.27.609902 — biophysics — Posted on 2024-08-28

696 Structural basis of inhibition of human NaV1.8 by the tarantula venom peptide Protoxin-I

Neumann, B.; McCarthy, S.; Gonen, S.

10.1101/2024.08.27.609828 — biophysics — Posted on 2024-08-28

697 Metastable Dynamics Emerge from Local Excitatory-Inhibitory Homeostasis in the Cortex at Rest

Pascoa dos Santos, F.; Verschure, P. F.

10.1101/2024.08.24.609501 — neuroscience — Posted on 2024-08-28

698 3D-Printable Non-invasive Head Immobilization System for Non-Human Primates

Shahbazi, E.; Nguyen, D.; Swedan, T.; Ma, T.; Lafer-Sousa, R.; Dinh, A.; Azadi, R.; Ryan, A.; Afraz, A.

10.1101/2024.01.02.573832 — physiology — Posted on 2024-08-28

699 ANDES: a novel best-match approach for enhancing gene set analysis in embedding spaces

Li, L.; Dannenfelser, R.; Cruz, C.; Yao, V.

10.1101/2023.11.21.568145 — bioinformatics — Posted on 2024-08-28

700 Regional differences in cell characteristics in electric eel electric organs indicate electrocyte development with ventral to dorsal migration.

Senarat, S.; Matsumoto, A.; Sakaki, S.; Tsuzuki, D.; Uchida, K.; Kuwahara, M.; Hondo, E.; Iida, A.

10.1101/2024.08.21.606117 — developmental biology — Posted on 2024-08-28

701 Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice

Nguyen, Q. A. T.; Rocha, A.; Chhor, R.; Yamashita, Y.; Stadler, C.; Pontrello, C.; Yang, H.; Haga-Yamanaka, S.

10.1101/2023.09.27.559655 — neuroscience — Posted on 2024-08-28

702 Predictably manipulating photoreceptor light responses to reveal their role in downstream visual responses

Chen, Q.; Ingram, N. T.; Baudin, J.; Angueyra, J. M.; Sinha, R.; Rieke, F.

10.1101/2023.10.20.563304 — neuroscience — Posted on 2024-08-28

703 Senescent cell-derived extracellular vesicles inhibit cancer recurrence by coordinating immune surveillance

Ziglari, T.; Calistri, N.; Finan, J. M.; Derrick, D.; Nakayasu, E. S.; Burnet, M.; Kyle, J. E.; Hoare, M. W.; Heiser, L.; Pucci, F.

10.1101/2022.06.30.498366 — cancer biology — Posted on 2024-08-28

704 Autosomal suppression of sex-ratio meiotic drive influences the dynamics of X and Y chromosome coevolution

Gupta, A.; Unckless, R.

10.1101/2023.09.28.559847 — genetics — Posted on 2024-08-28

705 Genomes of nitrogen-fixing eukaryotes reveal a non-canonical model of organellogenesis

Frail, S.; Steele-Ogus, M.; Doenier, J.; Moulin, S. L. Y.; Braukmann, T.; Xu, S.; Yeh, E.

10.1101/2024.08.27.609708 — evolutionary biology — Posted on 2024-08-28

706 Ecology and abundant occurrence of Genea (Pyronemataceae) in western Oregon, U.S.A.

Dawson, H. R.; Dawson, H. A.

10.1101/2024.07.29.604843 — ecology — Posted on 2024-08-28

707 PfMORC protein regulates chromatin accessibility and transcriptional repression in the human malaria parasite, Plasmodium falciparum

Chahine, Z. M.; Gupta, M.; Lenz, T.; Hollin, T.; Abel, S.; Banks, C.; Saraf, A.; Prudhomme, J.; Bhanvadia, S.; Florens, L.; Le Roch, K. G.

10.1101/2023.09.11.557253 — microbiology — Posted on 2024-08-28

708 Foundation model of neural activity predicts response to new stimulus types and anatomy

Wang, E. Y.; Fahey, P. G.; Ding, Z.; Papadopoulos, S.; Ponder, K.; Weis, M.; Chang, A.; Muhammad, T.; Patel, S.; Ding, Z.; Tran, D. T.; Fu, J.; Schneider-Mizell, C. M.; Reid, R. C.; Collman, F.; da Costa, N. M.; Franke, K.; Ecker, A. S.; Reimer, J.; Pitkow, X.; Sinz, F. H.; Tolias, A. S.

10.1101/2023.03.21.533548 — neuroscience — Posted on 2024-08-28

709 NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function

Rampinini, A. C.; Balboni, I.; Kepinska, O.; Berthele, R.; Golestani, N.

10.1101/2024.08.27.609682 — neuroscience — Posted on 2024-08-28

710 Cell class-specific long-range axonal projections of neurons in mouse whisker-related somatosensory cortices

Liu, Y.; Bech, P.; Tamura, K.; Delez, L. T.; Crochet, S.; Petersen, C. C.

10.1101/2024.03.21.586078 — neuroscience — Posted on 2024-08-28

711 mosGraphGen: a novel tool to generate multi-omics signaling graphs to facilitate integrative and interpretable graph AI model development

Zhang, H.; Cao, D.; Chen, Z.; Zhang, Z.; Chen, Y.; Sessions, C.; Cruchaga, C.; Payne, P. R.; Li, G.; Province, M.; Li, F.

10.1101/2024.05.15.594360 — systems biology — Posted on 2024-08-28

712 A molecular proximity sensor based on an engineered, dual-component guide RNA

Choi, J.; Chen, W.; Liao, H.; Li, X.; Shendure, J.

10.1101/2023.08.14.553235 — synthetic biology — Posted on 2024-08-28

713 Multi-gradient Permutation Survival Analysis Identifies Mitosis and Immune Signatures Steadily Associated with Cancer Patient Prognosis

Cai, X.; Ye, Y.; Liu, X.; Fang, Z.; Chen, L.; Li, F.; Ji, H.

10.1101/2024.02.20.581166 — cancer biology — Posted on 2024-08-27

714 Recharacterization of RSL3 reveals that the selenoproteome is a druggable target in colorectal cancer

DeAngelo, S. L.; Zhao, L.; Dziechciarz, S.; Shin, M.; Solanki, S.; Balia, A.; El-Derany, M. O.; Castillo, C.; Qin, Y.; Das, N. K.; Bell, H. N.; Paulo, J. A.; Zhang, Y.; Rossiter, N. J.; McCulla, E. C.; He, J.; Talukder, I.; Ng, B. W.-L.; Schafer, Z. T.; Neamati, N.; Mancias, J. D.; Koutmos, M.; Shah, Y. M.

10.1101/2024.03.29.587381 — cancer biology — Posted on 2024-08-28

715 The inhibition of three distinct signaling pathways eliminates the oncogenic Tribbles homolog 2 from melanoma cells

Mayoral-Varo, V.; Orea-Soufi, A.; Jimenez, L.; Santos, B.; Serrao, G.; Jociles, M.; Obeso, S.; Ferreira, B.; Link, W.

10.1101/2024.07.17.603886 — cancer biology — Posted on 2024-08-28

716 Identification of BLM's Aggregation-Prone Nature and Its Similarity to Intrinsically Disordered Proteins: An In-silico Study

Sharma, S.; Yadav, S. S.; Nair, R. R.

10.1101/2024.07.16.603833 — bioinformatics — Posted on 2024-08-27

717 Protein sequence classification using natural language processing techniques

Perveen, H.; Weeds, J.

10.1101/2024.08.23.609306 — bioinformatics — Posted on 2024-08-27

718 Alligamycin A, an unprecedented antifungal β-lactone spiroketal macrolide from Streptomyces iranensis

Yang, Z.; Qiao, Y.; Strobech, E.; Morth, J. P.; Walther, G.; Jorgensen, T. S.; Peschel, G.; Rosenbaum, M. A.; Previtali, V.; Clausen, M. H.; Lukassen, M. V.; Gotfredsen, C. H.; Kurzai, O.; Weber, T.; Ding, L.

10.1101/2024.04.17.589928 — biochemistry — Posted on 2024-08-27

719 DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

Dearlove, E. L.; Chatrin, C.; Buetow, L.; Ahmed, S. F.; Schmidt, T.; Bushell, M.; Smith, B. O.; Huang, D. T.

10.1101/2024.04.02.587769 — biochemistry — Posted on 2024-08-28

720 A sperm-enriched 5'fragment of tRNA-Valine regulates preimplantation embryonic transcriptome and development

Liu, S.; Holmes, A. D.; Katzman, S.; Sharma, U.

10.1101/2024.08.08.607197 — developmental biology — Posted on 2024-08-27

721 Rapalink-1 reveals novel mTOR-dependent genes and an agmatinergic axis-based metabolic feedback regulating mTOR activity and lifespan

Kumar, J.; Rallis, C.

10.1101/2024.07.20.604404 — cell biology — Posted on 2024-08-27

722 Cyclic Electromagnetic DNA Simulation (CEDS) can regulate the Functions of Different miRNAs and DNA Motifs: Protein Signaling Pathways in RAW 264.7 Cells detected by IP-HPLC Analysis

Kim, Y. S.; Lee, S. K.

10.1101/2024.08.23.609321 — molecular biology — Posted on 2024-08-27

723 Using artificial intelligence to document the hidden RNA virosphere

Hou, X.; He, Y.; Fang, P.; Mei, S.-Q.; Xu, Z.; Wu, W.-C.; Tian, J.-H.; Zhang, S.; Zeng, Z.-Y.; Gou, Q.-Y.; Xin, G.-Y.; Le, S.-J.; Xia, Y.-Y.; Zhou, Y.-L.; Hui, F.-M.; Pan, Y.-F.; Eden, J.-S.; Yang, Z.-H.; Han, C.; Shu, Y.-L.; Guo, D.; Li, J.; Holmes, E. C.; Li, Z.-R.; Shi, M.

10.1101/2023.04.18.537342 — microbiology — Posted on 2024-08-27

724 Bacillus velezensis HBXN2020 alleviates Salmonella Typhimurium infection in mice by improving intestinal barrier integrity and reducing inflammation

Wang, L.; Wang, H.; Li, X.; Zhu, M.; Gao, D.; Hu, D.; Xiong, Z.; Li, X.; Qian, P.

10.1101/2023.11.21.568052 — microbiology — Posted on 2024-08-27

725 Vascular FLRT2 regulates venous-mediated angiogenic expansion and CNS barriergenesis

Llao-Cid, C.; Peguera, B.; Kobialka, P.; Decker, L.; Vogenstahl, J.; Alivodej, N.; Srivastava, S.; Jin, J.; Kirchmaier, B.; Milla, C.; Schlierbach, H.; Schaenzer, A.; Acker, T.; Segarra, M.; Acker-Palmer, A.

10.1101/2024.08.27.609862 — neuroscience — Posted on 2024-08-27

726 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation

Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.

10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-08-27

727 Dissociating External and Internal Attentional Selection

Arora, K.; Gayet, S.; Kenemans, J. L.; Van der Stigchel, S.; Chota, S.

10.1101/2024.08.27.609883 — neuroscience — Posted on 2024-08-27

728 Therapeutic potential of red blood cell-derived extracellular vesicles in reducing neuroinflammation and protecting against retinal degeneration.

Sekar, R.; Cioanca, A. V.; Yang, Y.; Kamath, K. S.; Carroll, L.; Natoli, R.; Wooff, Y.

10.1101/2024.08.06.606930 — neuroscience — Posted on 2024-08-28

729 Type 1 interferon perturbates clonal competition by reshaping human blood development

Lama, C.; Isakov, D.; Rosenberg, S.; Quijada-Alamo, M.; Saurty-Seerunghen, M. S.; Moein, S.; Abera, T.-A.; Sakaguchi, O.; Totwani, M.; Freed, G.; Poon, C.-L.; Parghi, N.; Kubas-Meyer, A.; Xie, A. X.; Omar, M.; Choi, D.; Castillo-Tokumori, F.; Abu-Zeinah, G.; Dillard, A.; Omans, N. D.; Dusaj, N. N.; Chamely, P.; Mimitou, E.; Smibert, P.; Kosiorek, H. E.; Dueck, A. C.; Weinberg, R.; Chaligne, R.; Marcellino, B.; Marchionni, L.; Patel, S.; Simonson, P. D.; Landau, D. A.; Wagenblast, E.; Hoffman, R.; Nam, A. S.

10.1101/2022.09.28.509751 — cancer biology — Posted on 2024-08-27

730 Implementation and calibration of spectroscopic single-molecule localization microscopy

Brenner, B.; Yeo, W.-H.; Lee, Y.; Kweon, J.; Sun, C.; Zhang, H. F.

10.1101/2024.08.15.608177 — bioengineering — Posted on 2024-08-27

731 Kinome screening identifies integrated stress response kinase EIF2AK1 / HRI as a negative regulator of PINK1 mitophagy signaling

Singh, P.; Agarwal, S.; Volpi, I.; Wilhelm, L. P.; Becchi, G.; Keenlyside, A.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.

10.1101/2023.03.20.533516 — biochemistry — Posted on 2024-08-27

732 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.

10.1101/2023.12.07.570640 — genetics — Posted on 2024-08-27

733 Phylogenomics of neglected flagellated protists supports a revised eukaryotic tree of life

Torruella, G.; Galindo, L. J.; Moreira, D.; Lopez-Garcia, P.

10.1101/2024.05.15.594285 — evolutionary biology — Posted on 2024-08-27

734 IDENTIFICATION OF AN EARLY SUBSET OF CEREBELLAR NUCLEI NEURONS IN MICE

Rahimi-Balaei, M.; Amiri, S.; Lamonerie, T.; Wu, S.-R.; Zoghbi, H. Y.; Consalez, G. G.; Goldowitz, D.; Marzban, H.

10.1101/212571 — developmental biology — Posted on 2024-08-27

735 Morphological Profiling Dataset of EU-OPENSCREEN Bioactive Compounds Over Multiple Imaging Sites and Cell Lines

10.1101/2024.08.27.609964 — cell biology — Posted on 2024-08-27

736 Full-length direct RNA sequencing uncovers stress-granule dependent RNA decay upon cellular stress

Dar, S. A.; Malla, S.; Martinek, V.; Payea, M. J.; Lee, C. T.-Y.; Martin, J.; Khandeshi, A. J.; Martindale, J. L.; Belair, C.; Maragkakis, M.

10.1101/2023.08.31.555629 — cell biology — Posted on 2024-08-27

737 Interplay Between FoxM1 and Dab2 Promotes Endothelial Cell Responses in Diabetic Wound Healing

Bhattacharjee, S.; Gao, J.; Lu, Y. W.; Eisa-Beygi, S.; Wu, H.; Li, K. S.; Birsner, A. E.; Wong, S.; Song, Y.; Shyy, J. Y.-J.; Cowan, D. B.; Wei, W.; Aikawa, M.; Shi, J.; Chen, H.

10.1101/2024.02.07.579019 — cell biology — Posted on 2024-08-27

738 Phagosome-mediated activation of STING during diverse bacterial infections

Ragland, S. A.; Kagan, J. C.

10.1101/2022.10.28.514268 — immunology — Posted on 2024-08-27

739 A Subcortical Model for Auditory Forward Masking with Efferent Control of Cochlear Gain

Maxwell, B. N.; Farhadi, A.; Brennan, M. H.; Svec, A.; Carney, L. H.

10.1101/2024.01.18.576173 — neuroscience — Posted on 2024-08-27

740 Super-Resolution Simplified: Sub-10nm Imaging Over Large Areas and Deep Penetration via SDC-OPR and DNA-PAINT

Zaza, C.; Joseph, M. D.; Dalby, O. P. L.; Walther, R. F.; Kolataj, K.; Chiarelli, G.; Pichaud, F.; Acuna, G. P.; Simoncelli, S.

10.1101/2024.08.26.609760 — biophysics — Posted on 2024-08-27

741 Gamma Approximation of Stratified Truncated Exact test (GASTE-test) & Application

Wendling, A.; Galiez, C.

10.1101/2024.07.26.605317 — bioinformatics — Posted on 2024-08-27

742 Coenzyme-Protein Interactions since Early Life

Sanchez Rocha, A. C.; Makarov, M.; Pravda, L.; Novotny, M.; Hlouchova, K.

10.1101/2023.10.28.563965 — bioinformatics — Posted on 2024-08-27

743 Relating strain amplitude, strain threshold and bone formation rate to exogenous forcing frequency

Prasad, J.; Aruva, A. M.; Shekhar, H.; Singh, S.; Singh, S. J.

10.1101/2023.10.08.561406 — bioengineering — Posted on 2024-08-27

744 Vibrio cholerae RbmB is an α-1,4-polysaccharide lyase with biofilm-dispersal activity against Vibrio Polysaccharide (VPS)

Weeresekera, R.; Moreau, A.; Huang, X.; Nam, K.-M.; Hinbest, A.; Huynh, Y.; Liu, X.; Ashwood, C.; Pepi, L. E.; Cegelski, L.; Yan, J.; Olson, R.

10.1101/2024.08.27.609776 — biochemistry — Posted on 2024-08-27

745 Multiple polyploidizations in Arabidopsis lyrata stabilized by long-range adaptive introgression across Eurasia

Scott, A. D.; Kolesnikova, U. K.; Glushkevich, A.; Steinmann, L.; Tikhomirov, N.; Pfordt, U.; Bohutinska, M.; Burns, R.; Seregin, A. P.; Kolar, F.; Schmickl, R.; Novikova, P. Y.

10.1101/2024.08.27.609292 — genomics — Posted on 2024-08-27

746 BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD

Tran, U.; Streets, A. J.; Smith, D.; Decker, E.; Kirschfink, A.; Izem, L.; Hassey, J.; Ruthland, B.; Valluru, M. K.; Bräsen, J. H.; Ott, E.; Epting, D.; Eisenberger, T.; Ong, A. C.; Bergmann, C.; Wessely, O.

10.1101/2024.08.27.608867 — genetics — Posted on 2024-08-27

747 Evolutionary dynamics of pro-inflammatory caspases in primates and rodents

Holland, M.; Rutkowski, R.; Levin, T.

10.1101/2024.06.19.599744 — evolutionary biology — Posted on 2024-08-27

748 Adaptation to yeast restriction through the evolution of resource acquisition, macronutrient reserve, and ovarian function

Dasgupta, P.; Koner, A.; Pal, R. S.; Pradhan, P. N.; Roychoudhury, K.; Nandy, B.

10.1101/2024.08.24.609539 — evolutionary biology — Posted on 2024-08-27

749 Characterisation of coastal reef fish assemblages across an estuarine-urbanisation gradient using underwater visual survey and environmental DNA metabarcoding

Pei, Y.-D.; Heard, J.; Xu, W.; Leung, S. K. K.; Yung, C. C. M.; Wyatt, A. S. J.

10.1101/2024.08.27.607512 — ecology — Posted on 2024-08-27

750 Spatiotemporal distribution of neural crest cells in the common wall lizard Podarcis muralis

Pranter, R.; Feiner, N.

10.1101/2024.05.24.595691 — developmental biology — Posted on 2024-08-27

751 Dimensionality reduction simplifies synaptic partner matching in an olfactory circuit

Lyu, C.; Li, Z.; Xu, C.; Wong, K. K. L.; Luginbuhl, D. J.; McLaughlin, C. N.; Xie, Q.; Li, T.; Li, H.; Luo, L.

10.1101/2024.08.27.609939 — developmental biology — Posted on 2024-08-27

752 Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis

Wan, Y.; El Kholtei, J.; Jenie, I.; Colomer-Rosell, M.; Liu, J.; Acedo, J. N.; Du, L. Y.; Codina-Tobias, M.; Wang, M.; Sawh, A.; Lin, E.; Chuang, T.-H.; Mango, S. E.; Yu, G.; Bintu, B.; Schier, A. F.

10.1101/2024.08.27.609868 — developmental biology — Posted on 2024-08-27

753 Dissecting the regulatory logic of specification and differentiation during vertebrate embryogenesis

Liu, J.; Castillo-Hair, S. M.; Du, L. Y.; Wang, Y.; Carte, A. N.; Colomer-Rosell, M.; Yin, C.; Seelig, G.; Schier, A. F.

10.1101/2024.08.27.609971 — developmental biology — Posted on 2024-08-27

754 A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution

Blanch, J. R.; Krishnamurthy, M.; McVey, M.

10.1101/2024.08.27.609911 — molecular biology — Posted on 2024-08-27

755 A novel chemogenomic screening platform for scalable antimalarial drug target identification

Bower-Lepts, C. A.; Rawat, M.; Keith, W. C.; Girling, G.; Luth, M. R.; Carolino, K.; Boroviak, K.; Coyle, R.; Schwach, F.; Smidt, C.; Bushell, E.; Moliner-Cubel, S.; Gomez-Lorenzo, M. D. G.; Gamo, F.-J.; Winzeler, E. A.; Billker, O.; Lee, M. C.; Rayner, J. C.

10.1101/2024.08.27.609875 — microbiology — Posted on 2024-08-27

756 Beyond bacterial paradigms: uncovering the functional significance and first biogenesis machinery of archaeal lipoproteins

Hong, Y.; Makarova, K. S.; Xu, R.; Pfeiffer, F.; Pohlschroder, M.

10.1101/2024.08.27.609747 — microbiology — Posted on 2024-08-27

757 Tracing active bugs in microbial communities by BONCAT and click chemistry-based enrichment of newly synthesised proteins

Hellwig, P.; Kautzner, D.; Heyer, R.; Dittrich, A.; Wibberg, D.; Busche, T.; Winkler, A.; Reichl, U.; Benndorf, D.

10.1101/2024.08.27.609880 — microbiology — Posted on 2024-08-27

758 Posteromedial cortical networks encode visuomotor prediction errors.

Takeuchi, R. F.; Sato, A. Y.; Ito, K. N.; Yokoyama, H.; Miyata, R.; Ueda, R.; Kitajima, K.; Kamaguchi, R.; Suzuki, T.; Isobe, K.; Honda, N.; Osakada, F.

10.1101/2022.08.16.504075 — neuroscience — Posted on 2024-08-27

759 Exosomes can modulate the early hyperexcitability in cortical neurons with ASD-associated Shank3 mutation.

Choudhary, A.; Rosh, I.; Hussein, Y.; Shemen, A.; Rike, W. A.; Zinger, A.; Offen, D.; Stern, S.

10.1101/2024.08.27.609917 — neuroscience — Posted on 2024-08-27

760 Therapeutic suppression of Tubb4a rescues H-ABC leukodystrophy

Sase, S.; Hacker, J. L.; Napit, P. R.; Woidill, S.; Bhagavatula, A.; Alessandro, A. D.; Almad, A.; Takanohashi, A.; Padiath, Q.; Marsh, E. D.; Vanderver, A.

10.1101/2024.08.27.609903 — neuroscience — Posted on 2024-08-27

761 Circuit firing homeostasis following synaptic perturbation ensures robust behavior

Hoagland, A.; Newman, Z. L.; Cai, Z.; Isacoff, E. Y.

10.1101/2024.08.27.609984 — neuroscience — Posted on 2024-08-27

762 NeuroSCAN: Exploring Neurodevelopment via Spatiotemporal Collation of Anatomical Networks

Koonce, N. L.; Emerson, S. E.; Bhaskar, D.; Kuchroo, M.; Moyle, M. W.; Arroyo-Morales, P.; Martinez, N. V.; Krishnaswamy, S.; Mohler, W.; Colon-Ramos, D.

10.1101/2024.08.27.609993 — neuroscience — Posted on 2024-08-27

763 Cargo quantification of functionalized DNA origami for therapeutic application

Young, O.; Dembele, H.; Rajwar, A.; Kwon, I. C.; Ryu, J. H.; Shih, W.; Zeng, Y.

10.1101/2024.08.27.609963 — synthetic biology — Posted on 2024-08-27

764 Comparative transcriptomics in ferns reveals key innovations and divergent evolution of secondary cell wall

Ali, Z.; Tan, Q. W.; Lim, P. K.; Chen, H.; Pfeifer, L.; Julca, I.; Lee, J.; Vinter, F.; Layens, A.; Alvarado, C.; de Vries, J.; de Vries, S.; Classen, B.; Mizrachi, E.; Motawie, M.; Joergensen, B.; Ulvskov, P.; Koh, T. S.; Chin, L. l.; van de Peer, Y.; Ho, B. C.; Sibout, R.; Mutwil, M.

10.1101/2024.08.27.609851 — plant biology — Posted on 2024-08-27

765 The role of phosphorylation and dephosphorylation in the regulation of Rubisco activase

Bhatnagar, N.; Chung, S. S.; Hodge, J.; Boyd, R.; Kim, S. Y.; Sands, M.; Leakey, A.; Ort, D. R.; Burgess, S. J.

10.1101/2024.08.27.609719 — plant biology — Posted on 2024-08-27

766 Hemi Manganese Exchangers 1 and 2 enable manganese import at the plasma membrane in cyanobacteria

Reis, M.; Brandenburg, F.; Knopp, M.; Flachbart, S.; Braeutigam, A.; Metzger, S.; Gould, S. B.; Eisenhut, M.

10.1101/2023.02.16.528846 — plant biology — Posted on 2024-08-27

767 Rate of force development is correlated with corticospinal excitability during explosive voluntary contractions.

Castelli, F.; Mian, O. S.; Bruton, A.; Chembila Valappil, A.; Hannah, R.; Tillin, N. A.

10.1101/2024.08.27.607589 — physiology — Posted on 2024-08-27

768 Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure

Lang, D.; Ni, H.; Medvedev, R.; Liu, F. V.; Alvarez-Baron, C. P.; Tyan, L.; Turner, D.; Warden, A.; Morotti, S.; Schrauth, T.; Chanda, B.; Kamp, T. J.; Robertson, G.; Grandi, E.; Glukhov, A. V.

10.1101/2024.04.14.589457 — physiology — Posted on 2024-08-27

769 Test-retest reliability of TMS motor evoked responses and silent periods during explosive voluntary isometric contractions.

Castelli, F.; Mian, O. S.; Bruton, A.; Chembila Valappil, A. C.; Tillin, N. A.

10.1101/2024.08.12.607577 — physiology — Posted on 2024-08-27

770 Mitochondrial sites of contact with the nucleus aid in chemotherapy evasion of glioblastoma cells

Strobbe, D.; Bueno, M.; De Vitis, C.; Hassan, S.; Faccenda, D.; Bruqi, K.; Romano, E.; Pedace, L.; Iurchenko, A. A.; Dhoot, G. K.; Bistrot, I. J.; Klamt, F.; Lenz, L. S.; Chiela, E. C. F.; Urso, P. I. D.; Lally, I.; Miele, E.; Falasca, L.; Nikolaev, S.; Mancini, R.; Roncaroli, F.; Lenz, G.; Campanella, M.

10.1101/2024.08.27.608373 — cancer biology — Posted on 2024-08-27

771 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

Mukherjee, A. K.; Dutta, S.; Singh, A.; Sharma, S.; Roy, S. S.; Sengupta, A.; Chatterjee, M.; Vinayagamurthy, S.; Bagri, S.; Khanna, D.; Verma, M.; Soni, D.; Budharaja, A.; Bhisade, S. K.; anand, V.; Perwez, A.; George, N.; Faruq, M.; Gupta, I.; Sabarinathan, R.; Chowdhury, S.

10.1101/2021.12.07.471419 — cancer biology — Posted on 2024-08-27

772 Preventing evolutionary rescue in cancer

Patil, S.; Ahmed, A.; Viossat, Y.; Noble, R. J.

10.1101/2023.11.22.568336 — cancer biology — Posted on 2024-08-27

773 EML4-ALK variant-specific genetic interactions shape lung tumorigenesis

Diaz-Jimenez, A.; Shuldiner, E. G.; Somogyi, K.; Gonzalez, O.; Akkas, F.; Murray, C. W.; Andrejka, L.; Tsai, M. K.; Brors, B.; Sivakumar, S.; Sisoudiya, S. D.; Sokol, E. S.; Petrov, D.; Winslow, M. M.; Sotillo, R.

10.1101/2024.08.26.609730 — cancer biology — Posted on 2024-08-27

774 Engineering of ATP synthase for enhancement of proton-to-ATP ratio

Ueno, H.; Yasuda, K.; Hamaguchi-Suzuki, N.; Marui, R.; Adachi, N.; Senda, T.; Murata, T.; Noji, H.

10.1101/2024.08.27.609901 — biophysics — Posted on 2024-08-27

775 An alternative mechanism for activation of innate immune signaling by MDA5

Quack, S.; Maity, S.; America, P. P. B.; Klein, M.; Herrero del Valle, A.; Singh, R.; Smitskamp, Q.; Papini, F. S.; Broedersz, C.; Roos, W.; Modis, Y.; Dulin, D.

10.1101/2024.08.27.609867 — biophysics — Posted on 2024-08-27

776 QuICSeedR: An R package for analyzing fluorophore-assisted seed amplification assay data

Li, M.; Bryant, D. N.; Gresch, S.; Milstein, M.; Christenson, P. R.; Lichtenberg, S. S.; Larsen, P. A.; Oh, S.-H.

10.1101/2024.08.27.609919 — bioinformatics — Posted on 2024-08-27

777 Extraction, Characterization, and Toxicological Assessment of Chemicals from Thermal Bill Paper: An In-Silico ADME and Daphnia pulex Study

Ramesh, U.; Bhat, A. V.; Ranganath, N.; Hosamane, A. C.; Selvam, A. A. A.

10.1101/2024.08.27.609942 — biochemistry — Posted on 2024-08-27

778 Bioorthogonal labeling of chitin in pathogenic Candida species reveals biochemical mechanisms of hyphal growth and homeostasis

Williams, C.; Carnahan, B. R.; Hyland, S. N.; Grimes, C. L.

10.1101/2024.08.27.609898 — biochemistry — Posted on 2024-08-27

779 FibrilPaint targets amyloid fibrils for ubiquitination

Dekker, F. A.; Aragnones Pedrola, J.; Poza-Rodriguez, A.; Mayer, G.; Singh, S.; Heesink, G.; Claessens, M. M. A. E.; Friedler, A.; Rudiger, S. G. D.

10.1101/2024.08.27.609886 — biochemistry — Posted on 2024-08-27

780 Training Harbor Seals to Participate in Vocal Learning Experiments in a Zoo

Ravignani, A.; Duengen, D.

10.1101/2024.08.27.609954 — animal behavior and cognition — Posted on 2024-08-27

781 Onset of infectiousness explains differences in transmissibility across Mycobacterium tuberculosis lineages

Windels, E. M.; Agüi, C. V.; de Jong, B. C.; Meehan, C. J.; Loiseau, C.; Goig, G. A.; Zwyer, M.; Borrell, S.; Brites, D.; Gagneux, S.; Stadler, T.

10.1101/2024.08.27.609909 — genomics — Posted on 2024-08-27

782 Temporally discordant chromatin accessibility and DNA demethylation define short and long-term enhancer regulation during cell fate specification

Guerin, L.; Scott, T. J.; Yap, J. A.; Johansson, A.; Puddu, F.; Charlesworth, T.; Simmons, A. J.; Yang, Y.; Lau, K.; Ihrie, R. A.; Hodges, E.

10.1101/2024.08.27.609789 — genomics — Posted on 2024-08-27

783 The role of β-defensin 103 (DEFB103) copy number variation in bull fertility

Sidekli, O.; Hollox, E. J.; Fair, S.; Meade, K.

10.1101/2024.08.27.609910 — genomics — Posted on 2024-08-27

784 Plasmid-borne mcr-1 and Replicative Transposition of Episomal and Chromosomal blaNDM-1, blaOXA-69, and blaOXA-23 Carbapenemases in a Clinical Acinetobacter baumannii Isolate

Mmatli, M.; Mbelle, N. M.; Osei Sekyere, J.

10.1101/2024.08.27.609937 — genomics — Posted on 2024-08-27

785 Gene expression and chromatin accessibility comparison in iPSC-derived microglia in African, European, and Amerindian genomes in Alzheimer's patients and controls.

Moura, S.; Nasciben, L. B.; Ramirez, A. M.; Coombs, L.; Rivero, J.; Van Booven, D. J.; DeRosa, B. A.; Hamilton-Nelson, K. L.; Whitehead, P. L.; Adams, L. D.; Starks, T. D.; Mena, P. R.; Illanes-Manrique, M.; Tejada, S.; Byrd, G. S.; Cornejo-Olivas, M. R.; Feliciano-Astacio, B. E.; Nuytemans, K.; Wang, L.; Pericak-Vance, M. A.; Dykxhoorn, D. M.; Rajabli, F.; Griswold, A. J.; Young, J. I.; Vance, J. M.

10.1101/2024.08.27.609943 — genomics — Posted on 2024-08-27

786 Mitigation of chytrid infection on tadpoles with the antimicrobial metabolites of Xenorhabdus szentirmaii

Ujszegi, J.; Boros, Z.; Harmos, K.; Magos, G.; Toth, A.; Voros, J.; Kasler, A.

10.1101/2024.08.27.609889 — ecology — Posted on 2024-08-27

787 Analysing drivers of worldwide tidal wetland change

Perrodin, L.; Otero, A. N.; Toor, M.; Canto, R.; Becker, M.; Dong, Y.; Worthington, T. A.; Murray, N. J.

10.1101/2024.08.27.609936 — ecology — Posted on 2024-08-27

788 Effects Of Aryl Hydrocarbon Receptor Ligand TCDD On Human Trophoblast Cell Development

Shukla, V.; Iqbal, K.; Okae, H.; Arima, T.; Soares, M. J.

10.1101/2024.08.27.609205 — developmental biology — Posted on 2024-08-27

789 A non-canonical CDK, Pho85 regulates the restart of the cell-cycle following stress

Jin, N.; Jin, Y.; Oikawa, Y.; Nakano, A.; Ohsumi, Y.; Weisman, L. S.

10.1101/2024.08.27.609989 — molecular biology — Posted on 2024-08-27

790 Heterologous Production of Cyprosin B in Nicotiana benthamiana: Unveiling the Role of the Plant-Specific Insert Domain in Protein Function and Subcellular Localization

Muthusamy, S.; Vetukuri, R. R.; Lundgren, A.; Kim, S.; Kalyandurg, P. B.; Strid, A.; Zhu, L.-H.; Brodelius, P.; Kanagarajan, S.

10.1101/2024.08.27.609932 — molecular biology — Posted on 2024-08-27

791 The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC

Richard, J.; Grunst, M. W.; Niu, L.; Diaz-Salinas, M. A.; Tolbert, W. D.; Marchitto, L.; Zhou, F.; Bourassa, C.; Yang, D.; Chiu, T.-J.; Chen, H.-C.; Benlarbi, M.; Beaudoin-Bussieres, G.; Gottumukkala, S.; Li, W.; Dionne, K.; Belanger, E.; Chatterjee, D.; Medjahed, H.; Hendrickson, W. A.; Sodroski, J.; Lang, Z. C.; Morton, A. J.; Huang, R. K.; Matthies, D.; Smith, A. B.; Mothes, W.; Munro, J.; Pazgier, M.; Finzi, A.

10.1101/2024.08.27.609961 — microbiology — Posted on 2024-08-27

792 Optimization of screening methods leads to the discovery of new viruses in black soldier flies (Hermetia illucens)

Pienaar, R. D.; Herrero, S.; Cerqueira de Araujo, A.; Krupa, F.; Abd-Alla, A. M. M.; Herniou, E. A.

10.1101/2024.08.27.609913 — microbiology — Posted on 2024-08-27

793 The gut microbiome of honey-producing wasps has converged on that of social bees

Holley, J.-a. C.; Martin, A. N.; Pham, A. T.; Schlauch, J.; Moran, N. A.

10.1101/2024.08.27.609949 — microbiology — Posted on 2024-08-27

794 Early steps of the biosynthesis of the anticancer antibiotic pleurotin

Weaver, J. A.; Alkhder, D.; Prasongpholchai, P.; Tadesse, M. D.; de los Santos, E. L. C.; Song, L.; Corre, C.; Alberti, F.

10.1101/2024.08.27.609176 — microbiology — Posted on 2024-08-27

795 HIF-alpha signaling mediates the macrophage inflammatory response during Leishmania major infection

Fry, L. G.; Washam, C. L.; Roys, H.; Bowlin, A. K.; Venugopal, G.; Bird, J. T.; Byrum, S. D.; Weinkopff, T.

10.1101/2024.08.27.605844 — microbiology — Posted on 2024-08-27

796 Rapid resistance evolution against phage cocktails

van der Steen, B. A.; Gralka, M.; Mulla, Y.

10.1101/2024.08.27.609872 — microbiology — Posted on 2024-08-27

797 Mice colonized with the defined microbial community OMM19.1 are susceptible to C. difficile infection without prior antibiotic treatment.

Chua, M. J.; Collins, J.

10.1101/2024.08.27.609948 — microbiology — Posted on 2024-08-27

798 Microbiome diversity, intra-mucosal bacteria and immune integration within normal and asthmatic airway mucosa

Moffatt, M. F.; Nishimura, T.; Cox, M. J.; McBrien, C. N.; Burke, C.; Cuthbertson, L.; Lewis, K. E.; Attanoos, R.; Davies, G. A.; Chung, K. F.; Robertus, J. L.; Ish-Horowicz, J. S.; Carroll, O.; Bozeman, J. M.; McGowan, A.; Hopkin, J. M.; Lathrop, G. M.; Riazalhosseini, Y.; Cookson, W. O.

10.1101/2024.08.27.609874 — microbiology — Posted on 2024-08-27

799 Uncovering novel functions of the enigmatic, abundant and active Anaerolineae in a salt marsh ecosystem

Payne, P. E.; Knobbe, L. N.; Chanton, P.; Zaugg, J.; Mortazavi, B.; Mason, O. U.

10.1101/2024.08.27.609934 — microbiology — Posted on 2024-08-27

800 Antibiotics change the growth rate heterogeneity and morphology of bacteria

Kals, M.; Kals, E.; Kotar, J.; Donald, A.; Mancini, L.; Cicuta, P.

10.1101/2024.08.27.609914 — microbiology — Posted on 2024-08-27

801 Development of a highly-sensitive method to detect the carriage of carbapenem-resistant Pseudomonas aeruginosa in humans

Shahab, S. N.; van Veen, A.; Kempenaars, N.; Rijfkogel, A.; Schmitt, H.; Saharman, Y. R.; Vos, M. C.; Karuniawati, A.; Severin, J. A.

10.1101/2024.08.27.609846 — microbiology — Posted on 2024-08-27

802 Distinct immune profiles in children living with HIV based on timing and duration of suppressive antiretroviral treatment

Lee, M. J.; Litchford, M. L.; Vendrame, E.; Vergara, R.; Ranganath, T.; Fish, C. S.; Chebet, D.; Langat, A.; Mburu, C.; Neary, J.; Benki, S. F.; Wamalwa, D.; John-Stewart, G.; Lehman, D.; Blish, C. A.

10.1101/2024.08.27.609833 — immunology — Posted on 2024-08-27

803 Regulation of Leucine-Rich Repeat Kinase 2 by inflammation and IL-4

Dikovskaya, D.; Pemberton, R.; Taylor, M.; Tasegian, A.; Zenevicuite, K.; Sammler, E.; Howden, A. J.; Alessi, D. R.; Swamy, M.

10.1101/2024.04.29.591170 — immunology — Posted on 2024-08-27

804 A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit

SUN, J.; ROJO-CORTES, F. R.; ULIAN-BENITEZ, S.; FORERO, M. G.; LI, G.; SINGH, D.; WANG, X.; CACHERO, S.; MOREIRA, M.; KAVANAGH, D.; JEFFERIS, G. S. X. E.; CROSET, V.; HIDALGO, A.

10.1101/2023.01.04.522695 — neuroscience — Posted on 2024-08-27

805 The evolution of wasp mimicry and biogeography in the genus Temnostoma (Diptera: Syrphidae)

Hadrava, J.; Klecka, J.; Moran, K.; Kleckova, I.; Kelso, S.; Etzbauer, C.; Skevington, J. H.; Mengual, X.

10.1101/2024.08.27.609869 — zoology — Posted on 2024-08-27

806 A fluorescent probe enables the discovery of improved antagonists targeting the intracellular allosteric site of the chemokine receptor CCR7

Wurnig, S. L.; Huber, M. E.; Weiler, C.; Baltrukevich, H.; Merten, N.; Stoetzel, I.; Chang, Y.; Klammer, R.; Baumjohann, D.; Kiermaier, E.; Kolb, P.; Kostenis, E.; Schiedel, M.; Hansen, F. K.

10.1101/2024.08.27.607356 — pharmacology and toxicology — Posted on 2024-08-27

807 Synchronous L1 retrotransposition events promote chromosomal crossover early in human tumorigenesis

Zumalave, S.; Santamarina, M.; Espasandin, N. P.; Garcia-Souto, D.; Temes, J.; Baker, T. M.; Valtierra, A. P.; Otero, I.; Rodriguez-Castro, J.; Oitaben, A.; Alvarez, E. G.; Otero, P.; Diaz-Arias, I.; Martinez-Fernandez, M.; Van Loo, P.; Cristofari, G.; Rodriguez-Martin, B.; Tubio, J. M.

10.1101/2024.08.27.596794 — cancer biology — Posted on 2024-08-27

808 Comparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling

Yee, C.; Bartoelke, R.; Goertemaker, K.; Schmidt, J.; Leberecht, B.; Mouritsen, H.; Koch, K.-W.

10.1101/2024.08.27.609845 — biochemistry — Posted on 2024-08-27

809 Characterizing features affecting local ancestry inference performance in admixed populations

Honorato-Mauer, J.; Shah, N. N.; Maihofer, A. X.; Zai, C. C.; Belangero, S.; Nievergelt, C. M.; Psychiatric Genomics Consortium for PTSD Ancestry Working Group, ; Santoro, M.; Atkinson, E. G.

10.1101/2024.08.26.609770 — genomics — Posted on 2024-08-27

810 Functional and evolutionary constraints of wtf killer meiotic drivers

Srinivasa, A. N.; Campbell, S.; Venkatesan, S.; Nuckolls, N. L.; Lange, J. J.; Halfmann, R.; Zanders, S. E.

10.1101/2024.08.27.609905 — genetics — Posted on 2024-08-27

811 Genomes of nitrogen-fixing eukaryotes reveal a non-canonical model of organellogenesis

Frail, S.; Steele-Ogus, M.; Doenier, J.; Moulin, S. L. Y.; Braukmann, T.; Xu, S.; Yeh, E.

10.1101/2024.08.27.609708 — evolutionary biology — Posted on 2024-08-27

812 Environmental DNA Transport at an Offshore Mesophotic Bank in the Northwestern Gulf of Mexico

McCartin, L. J.; Govindarajan, A. F.; McDermott, J. M.; Herrera, S.

10.1101/2024.08.26.609783 — ecology — Posted on 2024-08-27

813 GlycoRNA-L and glycoRNA-S mediate human monocyte adhesion via binding to Siglec-5

Fu, M.; Qian, Y.; Huang, E.; Schwartz, Z.; Tai, H.; Tillock, K.; Lei, T.

10.1101/2024.08.27.609838 — cell biology — Posted on 2024-08-27

814 IRF5 mediates adaptive immunity via altered glutamine metabolism, mTORC1 signaling and post-transcriptional regulation following T cell receptor activation

Brune, Z.; Lu, A.; Moss, M.; Brune, L.; Huang, A.; Matta, B.; Barnes, B. J.

10.1101/2024.08.26.609422 — immunology — Posted on 2024-08-27

815 Behavioral screening defines three molecular Parkinsonism subgroups in Drosophila

Kaempf, N.; Valadas, J. D. S.; Robberechts, P.; Schoovaerts, N.; Praschberger, R.; Ortega, A.; Kilic, A.; Chabot, D.; Pech, U.; Kuenen, S.; Vilain, S.; Baz, E.-S.; Singh, J.; Davis, J.; Liu, S.; Verstreken, P.

10.1101/2024.08.27.609924 — neuroscience — Posted on 2024-08-27

816 A robust evaluation of TDP-43, poly GP, cellular pathology, and behavior in a AAV-C9ORF72 (G4C2)66 mouse model

Thompson, E. G.; Spead, O. M.; Akerman, S. C.; Curcio, C.; Zaepfel, B. L.; Kent, E.; Philips, T.; Vijayakumar, B. G.; Zacco, A.; Zhou, W.; Nagappan, G.; Rothstein, J. D.

10.1101/2024.08.27.607409 — neuroscience — Posted on 2024-08-27

817 Birth order specified recruitment of motor circuits during spontaneous neural activity in zebrafish embryo

Abi Younes, M.; Rima, M.; Coutanceau, J.-p.; Peysson, N.; Hoseinkhani, F.; Rodrigues, E.; Bullier, E.; Legendre, P.; Mangin, J.-M.; Hong, E.

10.1101/2024.08.27.609675 — neuroscience — Posted on 2024-08-27

818 Anxious individuals are more sensitive to changes in outcome variability and value differences in dynamic environments

McCoy, B.; Lawson, R. P.

10.1101/2024.08.25.609575 — animal behavior and cognition — Posted on 2024-08-27

819 Cyclic Electromagnetic DNA Simulation (CEDS) targeting Telomere Repeat Sequence can enhance Anticancer Effect, while CEDS targeting Canonical E-box Sequence induce Oncogenic Effect in Cells

Kim, Y. S.; Lee, S. K.

10.1101/2024.08.25.609549 — molecular biology — Posted on 2024-08-27

820 Understanding the roles of secondary shell hotspots in protein-protein complexes

Jayadevan, P.; Arangasamy, Y.; Srinivasan, N.; Sowdhamini, R.

10.1101/2024.08.26.609822 — bioinformatics — Posted on 2024-08-27

821 YOLO-Behaviour: A simple, flexible framework to automatically quantify animal behaviours from videos

Chan, A. H. H.; Putra, P.; Schupp, H.; Köchling, J.; Strassheim, J.; Renner, B.; Schroeder, J.; Pearse, W. D.; Nakagawa, S.; Burke, T.; Griesser, M.; Meltzer, A.; Lubrano, S.; Kano, F.

10.1101/2024.08.26.609387 — animal behavior and cognition — Posted on 2024-08-27

822 Transcripts and genomic intervals associated with variation in metabolite abundance in maize leaves under field conditions

Mathivanan, R. K.; Pedersen, C.; Turkus, J.; Shrestha, N.; Torres-Rodriguez, J. V.; Mural, R. V.; Obata, T.; Schnable, J. C.

10.1101/2024.08.26.609532 — genomics — Posted on 2024-08-27

823 Targeting Liver Epsins Ameliorates Dyslipidemia in Atherosclerosis

Zhu, B.; Gupta, K.; Cui, K.; Wang, B.; Malovichko, M. V.; Han, X.; Li, K. S.; Wu, H.; Arulsamy, K. S.; Singh, B.; Gao, J.; Wong, S.; Cowan, D. B.; WANG, D.-Z.; Biddinger, S.; Srivastava, S.; Shi, J.; Chen, K.; Chen, H.

10.1101/2024.08.26.609742 — cell biology — Posted on 2024-08-27

824 Mining Yeast Diversity Unveils Novel Targets for Improved Heterologous Laccase Production in Saccharomyces cerevisiae

Wong, R. W. K.; Foo, M.; Lay, J. R. S.; Wai, T. L. T.; Moore, J.; Dutreux, F.; Molzahn, C.; Nislow, C.; Measday, V.; Schacherer, J.; Mayor, T.

10.1101/2024.08.26.609787 — molecular biology — Posted on 2024-08-27

825 Would you agree if N is three?On statistical inference for small N.

Psarou, E.; Katsanevaki, C.; Maris, E.; Fries, P.

10.1101/2024.08.26.609821 — neuroscience — Posted on 2024-08-27

826 Neural tracking of auditory statistical regularities is reduced in adults with dyslexia

Ringer, H.; Sammler, D.; Daikoku, T.

10.1101/2024.08.26.609678 — neuroscience — Posted on 2024-08-27

827 Assessing neuronal correlates of salience and their adaptability with naturalistic textures in macaque V1 and V2

Davila, A.; Kohn, A.

10.1101/2024.08.26.609744 — neuroscience — Posted on 2024-08-27

828 Acetate enhances spatial memory in females via sex- and brain region-specific epigenetic and transcriptional remodeling

Periandri, E.; Dodson, K.; Vitorino, F.; Garcia, B.; Glastad, K.; Egervari, G.

10.1101/2024.08.26.609729 — neuroscience — Posted on 2024-08-27

829 Center-surround inhibition by expectation: a neuro-computational account

Huang, L.; Shen, S.; Sun, Y.; Ou, S.; Zhang, R.; de Lange, F. P.; ZHANG, X.

10.1101/2024.08.26.609781 — neuroscience — Posted on 2024-08-27

830 Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state

Watanabe, K.; Yamano, M.; Miyamoto, J.; Ohue-Kitano, R.; Masujima, Y.; Sasahara, D.; Mouri, Y.; Kono, N.; Inuki, S.; Osakada, F.; Nagaoka, K.; Aoki, J.; Sugiura, Y.; Ohno, H.; Kondoh, E.; Kimura, I.

10.1101/2024.08.26.609823 — physiology — Posted on 2024-08-27

831 Vapor-based Fixation of Pulmonary Tissue in its Physiological State: A Novel Approach to Histological Validation of Ultra High Resolution Phase Contrast CT in Human Sized Lungs

Dullin, C.; Reiser, J.; Wagner, W.; Longo, E.; Prasek, M.; Contillo, A.; Sodini, N.; Dreossi, D.; Confalonieri, P.; Salton, F.; Confalonieri, M.; Baratella, E.; Cova, M.; Benke, C.; Sagar, M. M. R.; D'Amico, L.; Albers, J.; Svetlove, A.; Flisikowska, T.; Flisikowski, K.; Wielpuetz, M. O.; Biederer, J.; Kauczor, H.-U.; Zanconati, F.; Tromba, G.

10.1101/2024.08.26.609748 — pathology — Posted on 2024-08-27

832 H3K27M diffuse midline glioma is homologous recombination defective and sensitized to radiotherapy and NK cell-mediated antitumor immunity by PARP inhibition

Guo, Y.; Li, Z.; Parsels, L. A.; Wang, Z.; Parsels, J. D.; Dalvi, A.; The, S.; Hu, N.; Valvo, V. M.; Doherty, R.; Peterson, E.; Wang, X.; Venkataraman, S.; Agnihotri, S.; Venneti, S.; Wahl, D.; Green, M. D.; Lawrence, T. S.; Koschmann, C.; Morgan, M. A.; Zhang, Q.

10.1101/2024.08.26.609803 — cancer biology — Posted on 2024-08-27

833 Pericytes orchestrate a tumor-restraining microenvironment in glioblastoma

Braun, S.; Bolivar, P.; Oudenaarden, C.; Sjolund, J.; Bocci, M.; Harbst, K.; Talkhoncheh, M. S.; Phung, B.; Cordero, E.; Rosberg, R.; Johansson, E.; Jonsson, G.; Pietras, A.; Pietras, K.

10.1101/2024.08.26.609765 — cancer biology — Posted on 2024-08-27

834 Protein target search diffusion-association/dissociation free energy landscape around DNA binding site with flanking sequences

Wan, B.; Yu, J.

10.1101/2024.08.26.609820 — biophysics — Posted on 2024-08-27

835 Prewetting couples membrane and protein phase transitions to greatly enhance coexistence in models and cells.

Bagheri, Y.; Rouches, M.; Machta, B.; Veatch, S. L.

10.1101/2024.08.26.609758 — biophysics — Posted on 2024-08-27

836 rpcFold: residual parallel convolutional neural network to decipher RNA folding from RNA sequence

Sharma, N.; Mitra, P.

10.1101/2024.08.26.609824 — bioinformatics — Posted on 2024-08-27

837 pyVIPER: A fast and scalable Python package for rank-based enrichment analysis of single-cell RNASeq data

Wang, A. L. E.; Lin, Z.; Zanella, L.; Vlahos, L.; Anglada-Girotto, M.; Zafar, A.; Noh, H.; Califano, A.; Vasciaveo, A.

10.1101/2024.08.25.609585 — bioinformatics — Posted on 2024-08-27

838 A long context RNA foundation model for predicting transcriptome architecture

Goodarzi, H.; Najafabadi, H. S.; Ramani, V.; Emad, A.; Namini, A.; Naghipourfar, M.; Wang, S.; Choi, B.; Saberi, A.

10.1101/2024.08.26.609813 — bioinformatics — Posted on 2024-08-27

839 A Bioinformatician, Computer Scientist, and Geneticist lead bioinformatic tool development - which one is better?

Gardner, P. P.

10.1101/2024.08.25.609622 — bioinformatics — Posted on 2024-08-27

840 Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to nifedipine and amlodipine drugs

Readhead, C.; Mahler, S.; Dong, Z.; Sato, Y.; Yang, C.; Bronner, M. E.

10.1101/2024.08.26.609812 — bioengineering — Posted on 2024-08-27

841 A 3D-printed handheld device for quick citrus tissue lysis and nucleic acid extraction

Liu, C.-W.; Kalish, B.; Bodaghi, S.; Vidalakis, G.; Tsutsui, H.

10.1101/2024.08.26.609775 — bioengineering — Posted on 2024-08-27

842 Haplotype-resolved genome assembly of upland switchgrass provides insights into cold tolerance

Wu, B.; Luo, D.; Yue, Y.; Yan, H.; He, M.; Ma, X.; Zhao, B.; Xu, B.; Zhu, J.; Wang, J.; Jia, J.; Sun, M.; Xie, Z.; Wang, X.; Huang, L.

10.1101/2024.08.26.609807 — genomics — Posted on 2024-08-27

843 Epididymis-specific RNase A family genes regulate fertility and small RNA processing

Shaffer, J. F.; Gupta, A.; Kharkwal, G.; Linares, E. E.; Holmes, A. D.; Sharma, U.

10.1101/2024.08.26.608813 — genetics — Posted on 2024-08-27

844 The KU70-SAP domain has an overlapping function with DNA-PKcs in limiting the lateral movement of KU along DNA

Zhu, Y.; Lee, B. J.; Fujii, S.; Jonchhe, S.; Zhang, H.; Li, A.; Wang, K. J.; Rothenberg, E.; Modesti, M.; Zha, S.

10.1101/2024.08.26.609806 — genetics — Posted on 2024-08-27

845 A new tool in a toolbox: Addressing challenges in high-throughput microbiota surveys across diverse wild insects

Buczek, M.; Kolasa, M. R.; Prus-Frankowska, M.; Lipowska, M.; Nowak, K. H.; Azarbad, H.; Franco, D. C.; Marszalek, M.; Roslin, T.; Michalik, A.; Lukasik, P.

10.1101/2024.08.26.609764 — ecology — Posted on 2024-08-27

846 Modeling the benefits of virus discovery and pandemic virus identification

Jeyapragasan, G.; Graabak, J.; Luby, S.; Esvelt, K. M.

10.1101/2024.08.26.609801 — ecology — Posted on 2024-08-27

847 What lurks beneath the humped back? - The patterns of bacterial abundance, diversity and distribution across communities of a dipteran family

Nowak, K. H.; Hartop, E.; Prus-Frankowska, M.; Buczek, M.; Kolasa, M.; Łukasik, P.

10.1101/2024.08.26.609658 — ecology — Posted on 2024-08-27

848 Water volume, biological and PCR replicates influence the characterization of deep-sea pelagic fish communities.

Peres, P. A.; Bracken-Grissom, H.

10.1101/2024.08.26.609755 — ecology — Posted on 2024-08-27

849 Novel high throughput 3D ECM remodeling assay identifies MEK as key driver of fibrotic fibroblast activity

Liao, C.-y.; Hundscheid, J. H.; Crawford, J.; ten Dijke, P.; Coorneaert, B.; Danen, E.

10.1101/2024.08.26.609699 — cell biology — Posted on 2024-08-27

850 Metadichol induces CD14 Glycoprotein Expression in Human Embryonic Stem Cells and Fibroblasts

Raghavan, P. R. E.

10.1101/2024.08.26.609762 — cell biology — Posted on 2024-08-27

851 Hydrogen peroxide damage to scavenging function and ultrastructure of liver sinusoidal endothelial cells is prevented by n-acetyl-cysteine but not GSH

Kruse, L. D.; Holte, C. F.; Zapotoczny, B.; Struck, E. C.; Schuerstedt, J.; Hubner, W.; Huser, T.; Szafranska, K.

10.1101/2024.08.26.609175 — cell biology — Posted on 2024-08-27

852 Cyclic Electromagnetic DNA Simulation (CEDS) can enhance the Functions of Anticancer miR-26a-5p and miR-126-5p in RAW 264.7 cells

Kim, Y. S.; Lee, S. K.

10.1101/2024.08.25.609548 — molecular biology — Posted on 2024-08-27

853 Microbial Weathering Analysis of Anshun Tunbao Artifacts

Abudureyimu, P.; Luo, X.; Gui, C.; Liu, M.; Su, X.; Lan, D.; Chen, Z.; Lon, J. R.; Luo, J.

10.1101/2024.08.26.609815 — microbiology — Posted on 2024-08-27

854 Immunophenotypic changes in peripheral blood of colorectal cancer patients: a potential diagnostic marker for CD4+ monocytes

Thin, K. A.; Cross, A.; Angsuwatcharakon, P.; Mutirangura, A.; Puttipanyalears, C.; Pike, T.; Jones, R.; Skaife, P.; Edwards, S.

10.1101/2024.08.26.609793 — immunology — Posted on 2024-08-27

855 Sodium channel inhibitors alter the progress of tangle development in a mouse model of dementia

Hall, C. M.; Roberts, M.; Desai, R.; Cummings, D. M.; Bisland, J.; Whiting, P.; Smith, K. J.; Edwards, F. A.

10.1101/2024.08.26.609302 — neuroscience — Posted on 2024-08-27

856 Alterations in large-scale resting-state network nodes following transcranial focused ultrasound of deep brain structures

Gorka, S.; Jimmy, J.; Koning, K.; Phan, K. L.; Rotstein, N.; Hoang-Dang, B.; Halavi, S.; Spivak, N.; Monti, M.; Reggente, N.; Bookheimer, S.; Kuhn, T.

10.1101/2024.08.26.609720 — neuroscience — Posted on 2024-08-27

857 Neural correlates of age-related changes in social decisions from episodic memory

van Geen, C.; Cohen, M. S.; Lempert, K. M.; MacNear, K. A.; Reckers, F. M.; Zaneski, L.; Wolk, D. A.; Kable, J. W.

10.1101/2024.08.26.609251 — neuroscience — Posted on 2024-08-27

858 On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy

Chen, Y.; Litt, B.; Vitale, F.; Takano, H.

10.1101/2024.08.26.609726 — neuroscience — Posted on 2024-08-27

859 Photoperiodicity in Glucose Metabolism in the Human Brain

Pak, K.; Shin, S.; Kim, K.; Kim, J.; Nam, H. Y.; Nummenmaa, L.; Nuutila, P.; Liu, X.; Sun, L.

10.1101/2024.08.26.609495 — neuroscience — Posted on 2024-08-27

860 A theory of rapid behavioral inferences under the pressure of time

Hermundstad, A. M.; Młynarski, W. F.

10.1101/2024.08.26.609738 — neuroscience — Posted on 2024-08-27

861 Perception/action coupling is modulated by the age-related motor skills of the agent performing the action

Clavaud-Seon, N.; Guillon, Q.; Schmitz, C.

10.1101/2024.08.24.609171 — neuroscience — Posted on 2024-08-27

862 Decoding the elite soccer players psychological profile

Bonetti, L.; Vestberg, T.; Jafari, R.; Seghezzi, D.; Ingvar, M.; Kringelbach, M. L.; Filgueiras Goncalves, A.; Petrovic, P.

10.1101/2024.08.25.609552 — neuroscience — Posted on 2024-08-27

863 Antimycin A induces light hypersensitivity of photosystem II in the presence of QB-site binding herbicides

Imaizumi, K.; Takagi, D.; Ifuku, K.

10.1101/2024.08.26.609723 — plant biology — Posted on 2024-08-27

864 Identification and functional categorization of the most stably and most variably expressed genes and retained introns in Arabidopsis thaliana seedlings

Lin, W.-D.; Kanno, T.; Matzke, A. J. M.; Matzke, M.

10.1101/2024.08.26.608733 — plant biology — Posted on 2024-08-27

865 Maize genetic diversity identifies moisture-dependent root-branch signaling pathways

Scharwies, J. D.; Clarke, T.; Zheng, Z.; Dinneny, A.; Birkeland, S.; Veltman, M. A.; Sturrock, C. J.; Torres-Martinez, H. H.; Viana, W. G.; Khare, R.; Kieber, J.; Pandey, B. K. K.; Bennett, M. J.; Schnable, P. S.; Dinneny, J. R.

10.1101/2024.08.26.609741 — plant biology — Posted on 2024-08-27

866 Kinetic modeling of ethylene biosynthesis and signaling pathways in ripening tomato fruit

Nguyen, T. M. V.; Tran, D. T.; Mata, C. I.; Van de Poel, B.; Nicolai, B.; Hertog, M. L. A. T. M.

10.1101/2024.08.26.607967 — plant biology — Posted on 2024-08-27

867 Mycoplasma gallisepticum (MG) infection inhibits mitochondrial respiratory function in a wild songbird

Ramanathan, C.; Thomas, E.; Henschen, A. E.; Adelman, J. S.; Zhang, Y.

10.1101/2024.08.26.609819 — physiology — Posted on 2024-08-27

868 CXCL12 chemokine dimer signaling modulates acute myelogenous leukemia cell migration through altered receptor internalization

Drouillard, D.; Halyko, M.; Cinquegrani, E.; McAllister, D.; Peterson, F. C.; Marchese, A.; Dwinell, M. B.

10.1101/2024.08.26.609725 — cancer biology — Posted on 2024-08-27

869 Extracellular matrix stiffness determines the phenotypic behavior of dedifferentiated melanoma cells through a DDR1/2-dependent YAP mechanotransduction pathway

Lecacheur, M.; Berestjuk, I.; Carminati, A.; Bouvet, O.; Diazzi, S.; Biber, P.; Rovera, C.; Irondelle, M.; Larbret, F.; Prodhomme, V.; Girard, C. A.; Deckert, M.; Tartare-Deckert, S.

10.1101/2024.08.26.609700 — cancer biology — Posted on 2024-08-27

870 Foundation model for efficient biological discovery in single-molecule data

Li, J.; Zhang, L.; Johnson-Buck, A.; Walter, N. G.

10.1101/2024.08.26.609721 — biophysics — Posted on 2024-08-27

871 An Integrative Study to Investigate Sex-Specific Biomarkers in Bladder Cancer Patients

Wang, Y.; Bhandary, P.; Griffin, K.; Moore, J. H.; Li, X.; Wang, Z. P.

10.1101/2024.08.26.609709 — bioinformatics — Posted on 2024-08-27

872 VISTA Uncovers Missing Gene Expression and Spatial-induced Information for Spatial Transcriptomic Data Analysis

Liu, T.; Lin, Y.; Luo, X.; Sun, Y.; Zhao, H.

10.1101/2024.08.26.609718 — bioinformatics — Posted on 2024-08-27

873 Evaluating computational approaches for comparison of protein expression across cancer indications

Wang, J.; Tian, X.; Yu, W.; Pullman, B.; Bullen, J.; Hurt, E.; Zhong, W.

10.1101/2024.08.26.609731 — bioinformatics — Posted on 2024-08-27

874 Effects of injury size on local and systemic immune cell dynamics in volumetric muscle loss

Whitaker, R.; Sung, S.; Tylek, T.; Risser, G.; O'Brien, E.; Chua, P. E.; Li, T.; Petrie, R. J.; Binder-Markey, B.; Spiller, K.

10.1101/2024.08.26.609702 — bioengineering — Posted on 2024-08-27

875 Invertebrate species distributions in urban ecosystems are driven by habitat availability, not by anthropogenic drivers

Morpurgo, J.; Remme, R. P.; Mudde, Q. D.; Didaskalou, E. A.; Serwatowska, K. J.; Trimbos, K. B.; Hu, M.; van Bodegom, P. M.

10.1101/2024.08.26.609715 — ecology — Posted on 2024-08-27

876 En route activity of Chilean Elaenia, a long-distance migratory bird in South America

Cueto, V. R.; Gorosito, C. A.; Brown, G. M.; Jahn, A. E.

10.1101/2024.08.26.609733 — ecology — Posted on 2024-08-27

877 PCDHGC3 silencing promotes renal carcinoma metastasis via mTOR/HIF2a and lipid metabolism rewiring

Chiara, M.-D.; Celada, L.; Cubiella, T.; Salerno, L.; San-Juan-Guardado, J.; Murias, E.; Da Silva Torres, M.; Suarez-Priede, A.; Weiner, J. A.; Herrada-Manchon, H.; Fernandez, M. A.

10.1101/2024.08.26.609687 — cancer biology — Posted on 2024-08-27

878 Immunogenicity and protection efficacy of self-amplifying and circular mRNA vaccines for SARS-CoV-2

Singh, O. N.; Berry, U.; Joshi, G.; Asuru, T. R.; Chandrasekar, K.; Narayanan, S.; Srivastava, P.; Tiwari, M.; Chattopadhyay, S.; Mehdi, F.; Panda, B. N.; Nayak, D.; Mani, S.; Shrivastava, T.; Batra, G.; Ranjith-Kumar, C.; Guchhait, P.; Surjit, M.

10.1101/2024.08.23.609366 — microbiology — Posted on 2024-08-27

879 Early Hox Gene Expression in Echinoderms

Ezhova, O. V.; Ageenko, N. V.; Kiselev, K. V.; Lukinykh, A. I.; Malakhov, V. V.

10.1101/2024.08.26.609757 — developmental biology — Posted on 2024-08-27

880 Canonical Wnt signalling from the Area Opaca induces and maintains the Marginal Zone in pre-primitive-streak stage chick embryos

Fadaili, Y.; Lu, H.-C.; Lee, H. C.; Ryazapova, A.; Stern, C. D.

10.1101/2024.08.24.609497 — developmental biology — Posted on 2024-08-27

881 Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development

Patel, A.; Freville, A.; Rey, J. A.; Flynn, H. R.; Kousis, K.; Skehel, M. J.; Blackman, M.; Baker, D. A.

10.1101/2024.04.08.588616 — molecular biology — Posted on 2024-08-27

882 Metabolic capabilities are highly conserved among human nasal-associated Corynebacterium species in pangenomic analyses

Tran, T. H.; F. Escapa, I.; Roberts, A. Q.; Gao, W.; Obawemimo, A. C. C.; Segre, J. A.; Kong, H. H.; Conlan, S.; Kelly, M.; Lemon, K. P.

10.1101/2023.06.05.543719 — microbiology — Posted on 2024-08-27

883 Predictions of bimanual self-touch determine the temporal tuning of somatosensory perception

Cemeljic, N.; Job, X.; Kilteni, K.

10.1101/2024.06.25.600596 — neuroscience — Posted on 2024-08-27

884 Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.

Kumawat, A.; Tavazzani, E.; Lentini, G.; Trancuccio, A.; Kukavica, D.; Denegri, M.; Priori, S. G.; Camilloni, C.

10.1101/2024.03.13.584147 — biophysics — Posted on 2024-08-27

885 MorphLink: Bridging Cell Morphological Behaviors and Molecular Dynamics in Multi-modal Spatial Omics

Huang, J.; Yuan, C.; Jiang, J.; Chen, J.; Badve, S.; Gokmen-Polar, Y.; Segura, R. L.; Yan, X.; Lazar, A.; Gao, J.; Epstein, M.; Wang, L.; Hu, J.

10.1101/2024.08.24.609528 — bioinformatics — Posted on 2024-08-27

886 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle

Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.

10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-27

887 Kinome screening identifies integrated stress response kinase EIF2AK1 / HRI as a negative regulator of PINK1 mitophagy signaling

Singh, P.; Agarwal, S.; Volpi, I.; Wilhelm, L. P.; Becchi, G.; Keenlyside, A.; Macartney, T.; Toth, R.; Rousseau, A.; Masson, G.; Ganley, I. G.; Muqit, M. M. K.

10.1101/2023.03.20.533516 — biochemistry — Posted on 2024-08-27

888 Readaptation of mesenchymal stem cells to high stiffness and oxygen environments modulate the extracellular matrix

Caramelo, I.; Domingues, C.; Mendes, V. M.; Anjo, S. I.; Geraldo, M.; Cardoso, C. M. P.; Graos, M.; Manadas, B.

10.1101/2024.08.26.609692 — cell biology — Posted on 2024-08-27

889 Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/beta-catenin signaling

Ntourmas, S.; Sachs, M.; Paclikova, P.; Bruckner, M.; Bryja, V.; Behrens, J.; Bernkopf, D. B.

10.1101/2024.03.07.583872 — cell biology — Posted on 2024-08-27

890 SpinalTRAQ: A novel volumetric cervical spinal cord atlas identifies the corticospinal tract synaptic projectome in healthy and post-stroke mice

Poinsatte, K.; Kenwood, M.; Betz, D.; Nawaby, A.; Ajay, A. D.; Xu, W.; Plautz, E. J.; Kong, X.; Ramirez, D. M. O.; Goldberg, M. P.

10.1101/2024.08.23.609434 — neuroscience — Posted on 2024-08-27

891 Haemolymphatic tissues of captive boa constrictor (Boa constrictor): morphological features in healthy individuals and with Boid Inclusion Body Disease

Dervas, E.; Michalopoulou, E.; Thiele, T.; Baggio, F.; Hetzel, U.; Kipar, A.

10.1101/2024.08.26.609690 — pathology — Posted on 2024-08-27

892 BEHAV3D Tumor Profiler to map heterogeneous cancer cell behavior in the tumor microenvironment

Rios-Jimenez, E.; Zomer, A.; Collot, R.; Barrera Roman, M.; Ariese, H.; L. van Ineveld, R.; Kleinnijenhuis, M.; Bessler, N.; Johnson, H.; Rios, A.; Alieva, M.

10.1101/2024.08.23.609358 — cancer biology — Posted on 2024-08-27

893 Mechanism of expanded DNA recognition in xCas9

Hossain, K. A.; Nierzwicki, L.; Orozco, M.; Czub, J.; Palermo, G.

10.1101/2024.08.26.609653 — biophysics — Posted on 2024-08-27

894 Shared and distinct molecular effects of regulatory genetic variants provide insight into mechanisms of distal enhancer-promoter communication

Ray-Jones, H.; Song, Z.; Chan, L. T.; Haglund, A.; Artemov, P.; Della Rosa, M.; Ruje, L.; Burden, F.; Kreuzhuber, R.; Litovskikh, A.; Weyenbergh, E.; Brusselaers, Z.; Tan, V. X. H.; Frontini, M.; Wallace, C.; Malysheva, V.; Bottolo, L.; Vigorito, E.; Spivakov, M.

10.1101/2023.08.04.551251 — genetics — Posted on 2024-08-27

895 Is facultative sex is the best of both worlds in the parasitoid wasp Lysiphlebus fabarum?

Boulton, R. A.

10.1101/2024.02.25.581911 — evolutionary biology — Posted on 2024-08-27

896 Fitness defects due to cytosolic protein misfolding in S. cerevisiae can be alleviated by decreasing mitochondrial protein import capacity

Zaidi, Z.; Dash, D. P.; Sharma, A.; KUNDU, S.; Bhatt, S.; Rao, S.; Padia, K.; Rai, M.; Chakraborty, K.

10.1101/2024.08.26.609637 — molecular biology — Posted on 2024-08-27

897 Prediction tendency, eye movements, and attention in a unified framework of neural speech tracking

Schubert, J.; Gehmacher, Q.; Schmidt, F.; Hartmann, T.; Weisz, N.

10.1101/2023.06.27.546746 — neuroscience — Posted on 2024-08-27

898 Binding of a pathogen effector to rice Exo70 proteins tethered to the NOI/RIN4 integrated domain of the NLR receptor Pii2 confers immunity against fungi

Fujisaki, K.; Abe, Y.; Sugihara, Y.; Nemoto, K.; Ito, K.; Kanzaki, E.; Ishikawa, K.; Iwai, M.; Utsushi, H.; Saitoh, H.; Takagi, H.; Takeda, T.; Abe, A.; Zheng, S.; Białas, A.; Banfield, M. J.; Kamoun, S.; Terauchi, R.

10.1101/239400 — plant biology — Posted on 2024-08-27

899 Multiple Protein Structure Alignment at Scale with FoldMason

Gilchrist, C. L. M.; Mirdita, M.; Steinegger, M.

10.1101/2024.08.01.606130 — bioinformatics — Posted on 2024-08-27

900 The genomic outcomes of hybridization vary over time within a monkeyflower radiation

Short, A. W.; Streisfeld, M. A.

10.1101/2024.08.26.609732 — evolutionary biology — Posted on 2024-08-27

901 Extinction probabilities of small structured populations: adequate short-term model predictions in Folsomia candida

Van Dooren, T. J.; Haccou, P.; Hermus, G.; Tully, T.

10.1101/2024.08.26.609669 — ecology — Posted on 2024-08-27

902 NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis

Weterings, S. D. C.; Eto, H.; de Leede, J.-D.; Giladi, A.; Hoekstra, M. E.; Beijk, W.; Liefting, E. J. M.; van den Anker, K. B.; van Rheenen, J.; van Oudenaarden, A.; Sonnen, K. F.

10.1101/2024.08.26.609553 — cell biology — Posted on 2024-08-27

903 Piezo activity levels need to be tightly regulated to maintain normal morphology and function in pericardial nephrocytes

Schulz, K.; Hazelton-Cavill, P.; Alornyo, K. K.; Edenhofer, I.; Lindenmeyer, M.; Lohr, C.; Huber, T. B.; Denholm, B.; Koehler, S.

10.1101/2021.10.23.465463 — cell biology — Posted on 2024-08-27

904 Dynamic modeling of EEG responses to natural speech reveals earlier processing of predictable words

Dou, J.; Anderson, A. J.; White, A. S.; Norman-Haignere, S. V.; Lalor, E. C.

10.1101/2024.08.26.609779 — neuroscience — Posted on 2024-08-26

905 Common DNA sequence variation influences epigenetic aging in African populations

Meeks, G. L.; Scelza, B.; Asnake, H. M.; Prall, S.; Patin, E.; Froment, A.; Fagny, M.; Quintana-Murci, L.; Henn, B. M.; Gopalan, S.

10.1101/2024.08.26.608843 — genetics — Posted on 2024-08-26

906 In vivo transition in chromatin accessibility during differentiation of deep-layer excitatory neurons in the neocortex

Sakai, S.; Maeda, Y.; Kawaji, K.; Suzuki, Y.; Gotoh, Y.; Kishi, Y.

10.1101/2024.08.26.609258 — developmental biology — Posted on 2024-08-26

907 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina

Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.

10.1101/2023.08.12.552902 — neuroscience — Posted on 2024-08-26

908 Transcriptomically-measured gene expression predicts physiological variation across single neurons in humans and mice

Kendrick, R. M.; Linderman, S.; Owen, S. F.

10.1101/2024.08.26.609746 — neuroscience — Posted on 2024-08-26

909 Impact of intragenic NRXN1 deletions on early cortical development

Dutan-Polit, L.; Gatford, N. J.; Carneiro, T.; Nagy, R.; Higgs, V.; APEX Consortia, ; Massrali, A.; Paul, A.; Fasolino, M.; Zhou, Z.; Flinter, F. A.; Adhya, D.; Bucan, M.; Baron-Cohen, S.; Srivastava, D. P.

10.1101/2024.08.26.609494 — neuroscience — Posted on 2024-08-26

910 A multidisciplinary on-farm survey of maize-bean intercropping highlights key considerations for reviving traditional agricultural systems.

Vazeux-Blumental, N.; Mathieu, L.; Trabac, T.; Palaffre, C.; Lagardere, B.; Carraretto, M.; Bauland, C.; Le Guilloux, M.; Paysant-Le Roux, C.; Caius, J.; Marmagne, A.; Enjalbert, J.; Flutre, T.; Le Cadre, E.; Parnaudeau, V.; Muller, D.; Moenne-Loccoz, Y.; Manicacci, D.; Tenaillon, M. I.

10.1101/2024.04.24.590929 — plant biology — Posted on 2024-08-26

911 Disruption of ultrasonic vocalization with systemic administration of the non-competitive N-methyl-d-aspartate receptor antagonist MK-801 in adult male mice

Tamura, R.; Ujihara, Y.; Yamamoto, M.; Matsushima, S.; Kasahara, H.; Nasukawa, D.; Hayashi, K.; Yamada, K.; Tanaka, M.; Toda, K.

10.1101/2024.08.25.609588 — pharmacology and toxicology — Posted on 2024-08-26

912 Oncogenic Ras activation in permissive somatic cells triggers rapid onset phenotypic plasticity and elicits a tumour-promoting neutrophil response

Elliot, A. M.; Ribeiro Bravo, I.; Astorga Johansson, J.; Hutton, E.; Cunningham, R.; Myllymaki, H.; Chang, K. Y.; Cholewa-Waclaw, J.; Zhao, Y.; Dobie, R.; Beltran, M.; Lewis, A.; Elks, P.; Hansen, C. G.; Henderson, N.; Feng, Y.

10.1101/2023.11.10.566547 — cancer biology — Posted on 2024-08-26

913 Phasor FLIM-FRET Analysis of Voltage Sensor Conformational Heterogeneity in hERG Potassium Channels

Dai, G.; Handlin, L. J.; Lessie, E. N.

10.1101/2024.05.17.594747 — biophysics — Posted on 2024-08-26

914 A criterion characterizing accumulated neurotoxicity of Aβ oligomers in Alzheimer's disease

Kuznetsov, A. V.

10.1101/2024.08.19.608707 — biophysics — Posted on 2024-08-26

915 Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

Wang, N.; Ockerman, F. P.; Zhou, L. Y.; Grove, M. L.; Alkis, T.; Barnard, J.; Bowler, R. P.; Clish, C. B.; Chung, S.; Drzymalla, E.; Evans, A. M.; Franceschini, N.; Gerszten, R. E.; Gillman, M. G.; Hutton, S. R.; Kelly, R. S.; Kooperberg, C.; Larson, M. G.; Lasky-Su, J. A.; Meyers, D. A.; Woodruff, P. G.; Reiner, A. P.; Rich, S. S.; Rotter, J.; Silverman, E. K.; Ramachandran, V. S.; Weiss, S. T.; Wong, K. E.; Wood, A. C.; Wu, L.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Yarden, R.; Blackwell, T.; Smith, A. V.; Chen, H.; Raffield, L. M.; Yu, B.

10.1101/2024.07.23.604849 — bioinformatics — Posted on 2024-08-26

916 Evaluating the Utilities of Foundation Models in Single-cell Data Analysis

Liu, T.; Li, K.; Wang, Y.; Li, H.; Zhao, H.

10.1101/2023.09.08.555192 — bioinformatics — Posted on 2024-08-26

917 How to train a post-processor for tandem mass spectrometry proteomics database search while maintaining control of the false discovery rate

Freestone, J. A.; Käll, L.; Noble, W. S.; Keich, U.

10.1101/2023.10.26.564068 — bioinformatics — Posted on 2024-08-26

918 Robustness and variability in Caenorhabditis elegans dauer gene expression

Corchado, J. C.; Godthi, A.; Selvarasu, K.; Prahlad, V.

10.1101/2024.08.15.608164 — bioinformatics — Posted on 2024-08-26

919 Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood

Stefanovic, F.; Brown, L.; MacDonald, J.; Bammler, T. K.; Rinchai, D.; Nguyen, S.; Zeng, Y.; Shinkawa, V.; Adams, K.; Chaussabel, D.; Berthier, E.; Haack, A. J.; Theberge, A. B.

10.1101/2024.08.24.609519 — bioengineering — Posted on 2024-08-26

920 Implementation and calibration of spectroscopic single-molecule localization microscopy

Brenner, B.; Yeo, W.-H.; Lee, Y.; Kweon, J.; Sun, C.; Zhang, H. F.

10.1101/2024.08.15.608177 — bioengineering — Posted on 2024-08-26

921 Distinct pathogenic influence of anti-HMGCR+ and anti-SRP+ immune-mediated necrotizing myopathy autoantibodies on engineered muscle function

Lad, H.; Esteban, E. M.; Tiper, Y.; Mahoudeau, A.; Xie, Z.; Tendrel, B.; Allenbach, Y.; Benveniste, O.; Gilbert, P. M.

10.1101/2024.08.26.609771 — bioengineering — Posted on 2024-08-26

922 The chromokinesin Kid (KIF22) forms a homodimer, moves processively along microtubules and transports double-strand DNA

Niwa, S.; Furusaki, N.; Kita, T.; Suzuki, Y.; Chiba, K.

10.1101/2024.03.13.584902 — biochemistry — Posted on 2024-08-26

923 The conformation of the nSrc specificity-determining loops in the Src and Abl SH3 domains are modulated by a WX conserved sequence motif

Longshore-Neate, F.; Ceravolo, C.; Masuga, C.; Tahti, E. F.; Blount, J. M.; Smith, S. N.; Amacher, J.

10.1101/2024.08.26.609727 — biochemistry — Posted on 2024-08-26

924 Molecular Mechanism of PP2A/B55α Phosphatase Inhibition by IER5

Cao, R.; Jones, D. T.; Pan, L.; Wang, S.; Padi, S. K. R.; Rawson, S.; Aster, J. C.; Blacklow, S. C.

10.1101/2023.08.29.555174 — biochemistry — Posted on 2024-08-26

925 CO2 protects cells from iron-Fenton oxidative DNA damage in E. coli and humans

Fleming, A. M.; Dingman, J. C.; Burrows, C. J.

10.1101/2024.08.26.609766 — biochemistry — Posted on 2024-08-26

926 Allopolyploidy expanded gene content but not pangenomic variation in the hexaploid oilseed Camelina sativa

Bird, K. A.; Brock, J. R.; Grabowski, P. P.; Harder, A. M.; Shu, S.; Barry, K.; Boston, L.; Daum, C.; Guo, J.; Lipzen, A.; Walstead, R.; Grimwood, J.; Schmutz, J.; Lu, C.; Comai, L.; McKay, J. K.; Pires, J. C.; Edger, P. P.; Lovell, J. T.; Kliebenstein, D. J.

10.1101/2024.08.13.607619 — genomics — Posted on 2024-08-26

927 Tumor suppressor heterozygosity and homologous recombination deficiency mediate resistance to front-line therapy in breast cancer

Safonov, A.; Marra, A.; Bandlamudi, C.; O'Leary, B.; Wubbenhorst, B.; Ferraro, E.; Moiso, E.; Lee, M.; An, J. A.-R.; Donoghue, M.; Will, M.; Pareja, F.; Nizialek, E.; Lukashchuk, N.; Sofianopoulou, E.; Liu, Y.; Huang, X.; Ahmed, M.; Mehine, M. M.; Ross, D.; Mandelker, D.; Schultz, N.; Berger, M.; Scaltriti, M.; Reis-Filho, J. S.; Li, B. T.; Offit, K.; Norton, L.; Shen, R.; Shah, S.; Maxwell, K. N.; Couch, F.; Domchek, S. M.; Solit, D. B.; Nathanson, K. L.; Robson, M. E.; Turner, N. C.; Chandarlapaty, S.; Razavi, P.

10.1101/2024.02.05.578934 — genomics — Posted on 2024-08-26

928 A Draft Pacific Ancestry Pangenome Reference

Littlefield, C. C.; Lazaro-Guevara, J. M.; Stucki, D.; Lansford, M.; Pezzolesi, M. H.; Taylor, E. J.; Wolfgramm, E. M. C.; Taloa, J.; Lao, K.; Dumaguit, C. D. C.; Ridge, P. G.; Tavana, J. P.; Holland, W. L.; Raphael, K. L.; Pezzolesi, M. G.

10.1101/2024.08.07.606392 — genomics — Posted on 2024-08-26

929 Electrostatic changes enabled the diversification of an exocyst subunit via protein complex escape

De la Concepcion, J. C.; Duverge, H.; Kim, Y.; Julian, J.; Xu, D.; Ikene, S. A.; Bianchi, A.; Grujic, N.; Papareddy, R.; Grishkovskaya, I.; Haselbach, D.; Murray, D.; Clavel, M.; Irwin, N.; Dagdas, Y.

10.1101/2024.08.26.609756 — evolutionary biology — Posted on 2024-08-26

930 Proteome asymmetry in mouse and human embryos before fate specification

Iwamoto-Stohl, L. K.; Petelski, A. A.; Meglicki, M.; Fu, A.; Khan, S.; Specht, H.; Huffman, G.; Derks, J.; Jorgensen, V.; Weatherbee, B. A.; Weberling, A.; Gantner, C. W.; Mandelbaum, R. S.; Paulson, R. J.; Lam, L.; Ahmady, A.; Vasquez, E. S.; Slavov, N.; Zernicka-Goetz, M.

10.1101/2024.08.26.609777 — developmental biology — Posted on 2024-08-26

931 H3K4me2 distinguishes a distinct class of enhancers during the maternal-to-zygotic transition

Hurton, M. D.; Miller, J. M.; Lee, M. T.

10.1101/2024.08.26.609713 — developmental biology — Posted on 2024-08-26

932 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour

Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.

10.1101/2024.02.19.581047 — cell biology — Posted on 2024-08-26

933 Opposing actomyosin pools generate cortical flows that establish epithelial polarity

Shi, Y.; Ohler, L. S.; de Jesus, B. N.; Dickinson, D. J.

10.1101/2024.08.26.609703 — cell biology — Posted on 2024-08-26

934 Subcellular context-specific tuning of actomyosin ring contractility within a common cytoplasm

Linehan, J.; Zampetaki, A.; Werner, M.; Heck, B.; Maddox, P.; Furthauer, S.; Maddox, A. S.

10.1101/2024.08.08.607200 — cell biology — Posted on 2024-08-26

935 Novel RNA-binding protein YebC enhances translation of proline-rich amino acid stretches in bacteria

Ignatov, D.; Shanmuganathan, V.; Ahmed-Begrich, R.; Alagesan, K.; Frese, C. K.; Wang, C.; Krause, K.; Charpentier, E.

10.1101/2024.08.26.607280 — molecular biology — Posted on 2024-08-26

936 Optimizing Electroporation Parameters for Efficient Delivery of Large Molecules into Pig Zygotes Using Fluorescent Dextrans from 3 to 2000 kDA

Fernandez, J. P.; Kues, W. A.; Hassel, P.; Kielau, P.

10.1101/2024.08.26.609025 — molecular biology — Posted on 2024-08-26

937 Acute Activation of Genes Through Transcriptional Condensates Impact Non-target Genes in a Chromatin Domain

Bohra, D.; Islam, Z.; Nidharshan, S.; Mazumder, A.; Notani, D.

10.1101/2024.08.26.609711 — molecular biology — Posted on 2024-08-26

938 The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites

Lo, J.; Vaeth, K. F.; Bhardwaj, G.; Mukherjee, N.; Russ, H. A.; Moore, J.; Taliaferro, M.

10.1101/2024.08.26.609768 — molecular biology — Posted on 2024-08-26

939 De novo design of potent inhibitors of Clostridioides difficile toxin B

Ragotte, R. J.; Tam, J.; Miletic, S.; Palou, R.; Weidle, C.; Li, Z.; Gloegl, M.; Beilhartz, G. L.; Liang, H.; Carr, K. D.; Borst, A. J.; Coventry, B.; Wang, X.; Rubinstein, J. L.; Tyers, M.; Melnyk, R. A.; Baker, D.

10.1101/2024.08.26.609740 — microbiology — Posted on 2024-08-26

940 ANALYSIS OF RESPIRATORY SYNCYTIAL VIRUS REVEALS CONSERVED RNA SECONDARY STRUCTURAL MOTIFS AND IMPACT VIRAL LIFECYCLE

Thornhill, E. M.; Andrews, R. J.; Lozier, Z.; Carino, E.; Rameix-Welti, M.-A.; Eleouet, J.-F.; Moss, W.; Verhoeven, D.

10.1101/2024.08.26.609688 — microbiology — Posted on 2024-08-26

941 Decoding non-human mammalian adaptive signatures of 2.3.4.4b H5N1 to assess its human adaptive potential

Nataraj, R.; Ashok, A. K.; Dey, A. A.; Kesavardhana, S.

10.1101/2024.08.26.609722 — microbiology — Posted on 2024-08-26

942 NSC95397 is a Novel HIV-1 Latency Reversing Agent

Nichols Doyle, R.; Yang, V.; Kayode, Y. I.; Damoiseaux, R.; Taylor, H. E.; Fregoso, O. I.

10.1101/2023.05.24.542213 — microbiology — Posted on 2024-08-26

943 AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid

Chen, D. F.; Roe, L. T.; Li, Y.; Borges, A. L.; Zhang, J. Y.; Babbar, P.; Maji, S.; Stevens, M. G. V.; Correy, G. J.; Diolaiti, M. E.; Smith, D. H.; Ashworth, A.; Stroud, R. M.; Kelly, M. J. S.; Bondy-Denomy, J.; Fraser, J. S.

10.1101/2024.08.26.609590 — microbiology — Posted on 2024-08-26

944 Persistent legacy effects on soil metagenomes facilitate plant adaptive responses to drought

Ginnan, N. A.; Custodio, V.; Gopaulchan, D.; Ford, N.; Salas-Gonzalez, I.; Jones, D. D.; Wells, D. M.; Moreno, A.; Castrillo, G.; Wagner, M. R.

10.1101/2024.08.26.609769 — microbiology — Posted on 2024-08-26

945 Tameness selection pressure affects gut virome diversity in mice

Biswa, B. B.; Fujiwara, K.; Toyoda, A.; Koide, T.

10.1101/2024.08.26.609628 — microbiology — Posted on 2024-08-26

946 A consortium-based approach to adaptive laboratory evolution of Acinetobacter baylyi ADP1 for lignin valorization

Maiti, S.; Singh, P.; J, V. P.; Muthukrishnan, A.; Blank, L. M.; Jayaraman, G.

10.1101/2024.08.26.609767 — microbiology — Posted on 2024-08-26

947 Neural Mechanisms of Creative Problem Solving: From Representational Change to Memory Formation

Becker, M.; Sommer, T.; Cabeza, R.

10.1101/2023.06.13.544774 — neuroscience — Posted on 2024-08-26

948 Satellite glial contact enhances differentiation and maturation of human iPSC-derived sensory neurons

LeBlang, C. J.; Pazyra-Murphy, M. F.; Silagi, E. S.; Dasgupta, S.; Tsolias, M.; Miller, T.; Petrova, V.; Zhen, S.; Jovanovic, V.; Castellano, D.; Gerrish, K.; Ormanoglu, P.; Tristan, C.; Singec, I.; Woolf, C. J.; Tasdemir-Yilmaz, O.; Segal, R. A.

10.1101/2024.07.24.604966 — neuroscience — Posted on 2024-08-26

949 A myelinic channel system for motor-driven organelle transport

Edgar, J. M.; Chapple, K. J.; Wirth, S.; Chen, Y.-H.; Gerwig, U.; Aicher, M. L.; Kim, Y.; Green, T.; Komarek, L.; Brown, A. M.; Pardo-Fernandez, L.; Crawford, C. L.; Smith, R. S.; Lee, J.; Werner, H. B.; Kassmann, C.; Davis, I.; Kneussel, M.; Brown, E. R.; Goebbels, S.; Nave, K.-A.

10.1101/2024.06.02.591488 — neuroscience — Posted on 2024-08-26

950 FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling

Khan, M. S. H.; Kim, S. Q.; Ross, R. C.; Corpodean, F.; Spann, R. A.; Albarado, D. A.; Fernandez-Kim, S. O.; Clarke, B.; Berthoud, H.-R.; Münzberg, H.; McDougal, D. H.; He, Y.; Yu, S.; Albaugh, V. L.; Soto, P.; Morrison, C. D.

10.1101/2024.03.05.583399 — neuroscience — Posted on 2024-08-26

951 Existence and Stability Criteria for Global Synchrony and for Synchrony in two Alternating Clusters of Pulse-Coupled Oscillators Updated to Include Conduction Delays

Vedururu Srinivas, A.; Canavier, C. C.

10.1101/2024.01.11.575222 — neuroscience — Posted on 2024-08-26

952 Motor neurons are dispensable for the assembly of a sensorimotor circuit for gaze stabilization

Goldblatt, D.; Rosti, B.; Hamling, K. R.; Leary, P.; Panchal, H.; Li, M.; Huang, S.; Quainoo, C.; Schoppik, D.

10.1101/2024.01.25.577261 — neuroscience — Posted on 2024-08-26

953 Focal control of non-invasive deep brain stimulation using multipolar temporal interference

Botzanowski, B.; ACERBO, E.; lehmann, s.; Kearsley, S. L.; Steiner, M.; Neufeld, E.; MISSEY, F.; Muller, L.; Jirsa, V.; Corneil, B. D.; Williamson, A.

10.1101/2023.09.05.556444 — neuroscience — Posted on 2024-08-26

954 Neuromodulator-induced Temperature Robustness in a Motor Pattern: a Comparative Study Between two Decapod Crustaceans

Stein, W.; Staedele, C.

10.1101/2023.11.23.568465 — neuroscience — Posted on 2024-08-26

955 A novel iPSC model of Bryant-Li-Bhoj neurodevelopmental syndrome demonstrates the role of histone H3.3 in neuronal differentiation and maturation

Sangree, A. K.; Angireddy, R.; Bryant, L. M.; Layo-Carris, D. E.; Lubin, E. E.; Wang, X. M.; Clark, K. J.; Durham, E. E.; Bhoj, E. J.

10.1101/2024.08.26.609745 — neuroscience — Posted on 2024-08-26

956 Behavior can be decoded across the cortex when individual differences are considered

Nakuci, J.; Yeon, J.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.

10.1101/2024.03.12.584674 — neuroscience — Posted on 2024-08-26

957 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action

Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.

10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-26

958 Phospho-proteomics identifies D-group MAP kinases as substrates of the Arabidopsis tyrosine phosphatase RLPH2

Labandera, A.-M.; Toth, R.; Mitchell, S.; Johnson, J.; Puyaubert, J.; Baudouin, E.; Uhrig, R. G.; Moorhead, G.

10.1101/2024.08.26.609716 — plant biology — Posted on 2024-08-26

959 Sex-specific regulation of the cardiac transcriptome by the protein phosphatase 2A regulatory subunit B55α

Sergienko, N. M.; Trewin, A. J.; Kiriazis, H.; Raaijmakers, A. J.; Donner, D. G.; Garside, V. C.; Smith, K. A.; Bell, J. R.; Mellor, K. M.; Delbridge, L. M.; McMullen, J. R.; Weeks, K. L.

10.1101/2024.05.05.592558 — physiology — Posted on 2024-08-26

960 Water and chloride as allosteric inhibitors in WNK kinase osmosensing

Goldsmith, E. J.; Teixeira, L. R.; Radha, A.; Humphreys, J. M.; He, H.

10.1101/2023.08.29.555411 — biophysics — Posted on 2024-08-26

961 Bats from the Colombian Caribbean Reveal a new subtype of Influenza A (H18N12)

Echeverri-De la Hoz, D.; Martinez-Bravo, C.; Gastelbondo-Pastrana, B.; Rivero, R.; Lopez, Y.; Hoyos, R.; Aleman, M.; Garay, E.; Bertel, V.; Arrieta, G.; Ramirez, J. D.; Mattar, S.

10.1101/2024.08.25.609627 — bioinformatics — Posted on 2024-08-26

962 Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung

Peak, K. E.; Rajaguru, P.; Khan, A.; Gleghorn, J. P.; Obaid, G.; Ferruzzi, J.; Varner, V. D.

10.1101/2024.08.22.609268 — bioengineering — Posted on 2024-08-26

963 CRISP: Correlation-Refined Image Segmentation Process

Briggs, J.; Jin, E.; Merrins, M. J.; Benninger, R. K.

10.1101/2024.08.23.609461 — bioengineering — Posted on 2024-08-26

964 Growth patterns of theoretical bite force and jaw musculature in southern sea otters (Enhydra lutris nereis)

Law, C.

10.1101/2024.08.23.609377 — developmental biology — Posted on 2024-08-26

965 Patient mutations in DRP1 perturb synaptic maturation of cortical neurons

Baum, T. B.; Bodnya, C.; Costanzo, J.; Gama, V.

10.1101/2024.08.23.609462 — cell biology — Posted on 2024-08-26

966 E. coli FtsN coordinates synthesis and degradation of septal peptidoglycan by partitioning between a synthesis track and a denuded glycan track

Lyu, Z.; Yang, X.; Yahashiri, A.; Ha, S.; McCausland, J. W.; Chen, X.; Britton, B. M.; Weiss, D. S.; Xiao, J.

10.1101/2024.05.13.594014 — microbiology — Posted on 2024-08-26

967 Sensory dependencies rapidly and autonomously yield generalizable representations in recurrent cortical-like networks

Rongala, U. B.; Jorntell, H.

10.1101/2024.07.17.603881 — neuroscience — Posted on 2024-08-26

968 Alternate RNA decoding results in stable and abundant proteins in mammals

Tsour, S.; Machne, R.; Leduc, A.; Widmer, S.; Slavov, N.

10.1101/2024.08.26.609665 — molecular biology — Posted on 2024-08-26

969 Androgen deprivation-mediated activation of AKT is enhanced in prostate cancer with TMPRSS2:ERG fusion

Ma, F.; Chen, S.; Calagua, C.; Arai, S.; Xie, F.; Voznesensky, O.; Poluben, L.; Corey, E.; Cai, C.; Wang, Y.; Einstein, D.; Taplin, M.-E.; Ye, H.; Sowalsky, A. G.; Russo, J.; Yuan, X.; Balk, S.

10.1101/2024.08.26.609679 — cancer biology — Posted on 2024-08-26

970 Extensive exploration of structure activity relationships for the SARS-CoV-2 macrodomain from shape-based fragment merging and active learning

Correy, G. J.; Rachman, M. M.; Togo, T.; Gahbauer, S.; Doruk, Y. U.; Stevens, M. G. V.; Jaishankar, P.; Kelley, B.; Goldman, B.; Schmidt, M.; Kramer, T.; Ashworth, A.; Riley, P.; Shoichet, B. K.; Renslo, A. R.; Walters, W. P.; Fraser, J. S.

10.1101/2024.08.25.609621 — biophysics — Posted on 2024-08-26

971 Biomechanical Evaluation of Temporomandibular Joint Implants Under Complete Mastication Cycle

Ghosh, R.; Chandra, G.; Verma, V.; Kaur, K.; Roychoudhury, A.; Mukherjee, S.; Chawla, A.; Mukherjee, K.

10.1101/2024.08.26.609607 — bioengineering — Posted on 2024-08-26

972 Molecular basis of pathogenicity of the recently emerged FCoV-23 coronavirus

Tortorici, M. A.; Choi, A.; Gibson, C.; Lee, J.; Brown, J. T.; Stewart, C.; Joshi, A.; Harari, S.; Willoughby, I.; Treichel, C.; Leif, E.; Bloom, J. D.; King, N. P.; Tait-Burkard, C.; Whittaker, G. R.; Veesler, D.

10.1101/2024.08.25.607996 — biochemistry — Posted on 2024-08-26

973 Functional maps of a genomic locus reveal confinement of an enhancer by its target gene.

Eder, M.; Moene, C. J. I.; Dauban, L.; Leemans, C.; van Steensel, B.

10.1101/2024.08.26.609360 — molecular biology — Posted on 2024-08-26

974 Using Dual-Coil TMS-EEG to Probe Bilateral Brain Mechanisms in Healthy Aging and Mild Cognitive Impairment

Morales-Torres, R.; Hovhannisyan, M.; Gamboa, O. L.; Dannhauer, M.; McAllister, M. L.; Roberts, K.; Li, Y.; Peterchev, A. V.; Woldorff, M. G.; Davis, S. W.

10.1101/2024.08.23.609391 — neuroscience — Posted on 2024-08-26

975 Natural Language Processing Applied to Spontaneous Recall of Famous Faces Reveals Memory Dysfunction in Temporal Lobe Epilepsy Patients

Tefera, E.; Borges Delfino de Souza, H.; Blewitt, C.; Mansoor, A.; Peters, H.; Teerawanichpol, P.; Henin, S.; Barr, W.; Johnson, S. B.; Liu, A.

10.1101/2024.08.23.609193 — neuroscience — Posted on 2024-08-26

976 The landscape of cellular clearance systems across human tissues and cell types is shaped by tissue-specific proteome needs

Vinogradov, E.; Ravkaie, L.; Edri, B.; Jubran, J.; Ben-Zvi, A.; Yeger-Lotem, E.

10.1101/2024.08.26.609695 — systems biology — Posted on 2024-08-26

977 Highjacked by a pseudoenzyme: How eudicot plants make indole

Florean, M.; Schultz, H.; Grabe, V.; Luck, K.; O'Connor, S. E.; Kollner, T. G.

10.1101/2024.08.26.609694 — plant biology — Posted on 2024-08-26

978 Epidrug Screening Identifies Type I PRMT Inhibitors as Modulators of Lysosomal Exocytosis and Drug Sensitivity in Cancers

Sergi, B.; Yuksel-Catal, N.; Ozcan, S. C.; Syed, H.; Duvvuri, U.; Kiselyov, K.; Acilan, C.

10.1101/2024.08.26.609671 — cancer biology — Posted on 2024-08-26

979 Comparative analysis of trans-chromosomic rodent models reveals improved somatic hypermutation and class-switch recombination in rats

Satofuka, H.; Abe, S.; Moriwaki, T.; Okada, A.; Kazuki, K.; Hamamichi, S.; Hiratsuka, M.; Hirabayashi, M.; Nakamura, K.; Sakuma, T.; Yamamoto, T.; Baba, Y.; Tomizuka, K.; Kazuki, Y.

10.1101/2024.08.26.609625 — bioengineering — Posted on 2024-08-26

980 Sustainable in situ extraction of microalgae-derived terpenoids using functionalized silica microparticles

Overmans, S.; Gallo, A.; Mishra, H.; Lauersen, K. J.

10.1101/2024.08.26.609696 — bioengineering — Posted on 2024-08-26

981 An exploration of unusual antimicrobial resistance phenotypes in Salmonella Typhi from Blantyre, Malawi reveals the ongoing role of IncHI1 plasmids

Zuza, A.; Wailan, A.; Anscombe, C.; Feasey, N. A.; Heinz, E.

10.1101/2024.08.26.609643 — genomics — Posted on 2024-08-26

982 LAT encodes T cell activation pathway balance

Rubin, A. J.; Dao, T. T.; Schueppert, A. V.; Regev, A.; Shalek, A. K.

10.1101/2024.08.26.609683 — genomics — Posted on 2024-08-26

983 Near-infrared spectroscopy discriminates mass-reared sterile and wild tsetse flies

Pagabeleguem, S.; Da, D. F.; Some, B. M.; Avelessi, M. S. P.; Djegbe, N. D. C.; Yoda, R. L.; Bagayogo, A.; MAIGA, H. M.; Churcher, T.; Dabire, R. K.

10.1101/2024.08.26.609677 — evolutionary biology — Posted on 2024-08-26

984 Foraging niche partitioning of three Myotis bat species and marine fish consumption by Myotis pilosus in a subtropical East Asian region

Wei, X.; Poon, E. S. K.; Chung, J. C. T.; Chan, D. T. C.; Shek, C. T.; Tsui, W. C.; Zhao, H.; Sin, S. Y. W.

10.1101/2024.08.26.609698 — ecology — Posted on 2024-08-26

985 Actin Polymerization Status Regulates Tendon Homeostasis through Myocardin-Related Transcription Factor-A

West, V.; Owen, K.; Inguito, K. L.; Ebron, K. M. M.; Reiner, T.; Mirack, C. E.; Le, C.; Marqueti, R. d. C.; Snipes, S.; Mousavizadeh, R.; Elliott, D.; Parreno, J.

10.1101/2024.08.26.609684 — cell biology — Posted on 2024-08-26

986 Readaptation of mesenchymal stem cells to high stiffness and oxygen environments modulate the extracellular matrix

Caramelo, I.; Domingues, C.; Mendes, V. M.; Anjo, S. I.; Geraldo, M.; Cardoso, C. M. P.; Graos, M.; Manadas, B.

10.1101/2024.08.26.609692 — cell biology — Posted on 2024-08-26

987 Fitness defects due to cytosolic protein misfolding in S. cerevisiae can be alleviated by decreasing mitochondrial protein import capacity

Zaidi, Z.; Dash, D. P.; Sharma, A.; KUNDU, S.; Bhatt, S.; Rao, S.; Padia, K.; Rai, M.; Chakraborty, K.

10.1101/2024.08.26.609637 — molecular biology — Posted on 2024-08-26

988 Identification and quantitative characterization of protein-DNA interactions with the native holdup assay: GATA1 regulation of the plasma membrane calcium pump

Zambo, B.; Morlet, B.; Negroni, L.; Mozner, O.; Sarkadi, B.; Trave, G.; Gogl, G.

10.1101/2024.08.26.609639 — molecular biology — Posted on 2024-08-26

989 Cyclic Electromagnetic DNA Simulation (CEDS) influences the functions of Long Oligo-dsDNAs and Plasmid DNAs

Lee, S. K.; Lee, D. G.; Kim, Y. S.

10.1101/2024.08.24.609489 — molecular biology — Posted on 2024-08-26

990 Synthetic enhancers reveal design principles of cell state specific regulatory elements in hematopoiesis

Fromel, R.; Ruhle, J.; Bernal Martinez, A.; Szu-Tu, C.; Pacheco Pastor, F.; Martinez Corral, R.; Velten, L.

10.1101/2024.08.26.609645 — molecular biology — Posted on 2024-08-26

991 FT-IR micro-spectroscopy for imaging the extracellular matrix composition in biofilms

de Bruin, S.; Hof, C.; van Loosdrecht, M.; Sousa, D. Z.; Lin, Y.

10.1101/2024.08.26.609418 — microbiology — Posted on 2024-08-26

992 Metagenomic insights into an enigmatic gammaproteobacterium that is important for carbon cycling in cave ecosystems worldwide

Jones, D. S.; Green, K. M.; Brown, A.; Havlena, Z. E.; Best, M. B.; Northup, D. E.; Mainiero, M.; Auch, B.

10.1101/2024.08.23.608578 — microbiology — Posted on 2024-08-26

993 Systematic Characterization of Transport Regulation in Escherichia coli across defined environmental cues

Binsfeld, C.; Olayo-Alarcon, R.; Wartel, M.; Stadler, M.; Mueller, C.; Brochado, A. R.

10.1101/2024.08.26.609649 — microbiology — Posted on 2024-08-26

994 Mtb specific HLA-E restricted T cells are induced during Mtb infection but not after BCG administration in non-human primates and humans

Voogd, L.; van Wolfswinkel, M.; Satti, I.; White, A. D.; Dijkman, K.; Gela, A.; van Meijgaarden, K. E.; Franken, K. L. M. C.; Marshall, J. L.; Ottenhoff, T. H. M.; Scriba, T.; McShane, H.; Sharpe, S. A.; Verreck, F. A. W.; Joosten, S. A.

10.1101/2024.08.26.609630 — immunology — Posted on 2024-08-26

995 RESPIRATORY SYNCYTIAL VIRUS NON-STRUCTURAL PROTEIN EXPRESSION ARE LIMITED IN NEUTROPHILS

Thornhill, E. M.; Verhoeven, D.

10.1101/2024.08.25.609617 — immunology — Posted on 2024-08-26

996 Investigating microscopic angioarchitecture in the human visual cortex in 3D with angioMASH tissue clearing and labelling

Hildebrand, S.; Franz, J.; Hoogen, H.; Capalbo, M.; Bethge, P.; Herrler, A.; Helmchen, F.; Roebroeck, A.

10.1101/2024.08.26.609648 — neuroscience — Posted on 2024-08-26

997 Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning

Jarrett, C. E.; Zwosta, K.; Wang, X.; Wolfensteller, U.; Iglesias, J. E.; von Kriegstein, K.; Ruge, H.

10.1101/2024.08.26.609333 — neuroscience — Posted on 2024-08-26

998 EEG Correlates of Cognitive Dynamics in Task Resumption after Interruptions: The Impact of Available Time and Flexibility

Ulku, S.; Getzmann, S.; Wascher, E.; Schneider, D.

10.1101/2024.08.26.609362 — neuroscience — Posted on 2024-08-26

999 Spatiotemporal Decomposition of Whole-Brain Alpha Traveling Waves

Li, Y.; HONG, B.

10.1101/2024.08.23.609472 — neuroscience — Posted on 2024-08-26

1000 Motion correction with subspace-based self-navigation for combined angiography, perfusion and structural imaging

Shen, Q.; Wu, W.; Chiew, M.; Ji, Y.; Woods, J. G.; Okell, T.

10.1101/2024.08.26.609650 — neuroscience — Posted on 2024-08-26

1001 A sleep disturbance method by novel objects in the home cage to minimize stress

Egebjerg, C.; Kolmos, M. G.; Abelson, K.; Kornum, B. R.

10.1101/2024.08.26.609657 — neuroscience — Posted on 2024-08-26

1002 Chloroplastic ROS bursts initiate salicylic acid biosynthesis in plant immunity

Roussin-Leveillee, C.; St-Amand, M.; Desbiens-Fortin, P.; Perreault, R.; Pelletier, A.; Gauthier, S.; Gaudreault-Lafleur, F.; Laforest-Lapointe, I.; Moffett, P.

10.1101/2024.08.26.609370 — plant biology — Posted on 2024-08-26

1003 SIRT5-mediated GLS and GDH desuccinylation attenuates autophagy in MAC-T cells induced by ammonia

Wang, Y.; Yang, H.; Gao, S.; Lu, G.; He, J.; Dong, J.; Zhang, X.; Liu, L.; Zhong, K.; Zha, G.; Han, L.; Guo, S.; Li, H.

10.1101/2024.08.26.609685 — physiology — Posted on 2024-08-26

1004 A marsh samphire (Salicornia europaea) extract induces a strictly sex-specific, Tor-signaling-dependent extension of lifespan and exhibits anti-obesogenic properties

Zadeh, N. T.; Knop, M.; Ulrich, L. M.; Bruchhaus, I.; Lang, R.; Luersen, K.; Rimbach, G.; Roeder, T.

10.1101/2024.08.25.609591 — physiology — Posted on 2024-08-26

1005 Expression and Function of Connexin 43 and Connexin 37 in the Murine Zona Glomerulosa

Stolting, G.; Hellmig, N.; Dinh, H. A.; Volkert, M.; Scholl, U. I.

10.1101/2024.08.26.608761 — physiology — Posted on 2024-08-26

1006 Pipeline for Assessing Tumor Immune Status Using Superplex Immunostaining and Spatial Immune Interaction Analysis

Xiao, C.; Zhou, R.; Chen, Q.; Hou, W.; Li, X.; Wang, Y.; Liu, L.; Wang, H.; Yao, X.; Xu, T.; Cao, F.; Yin, B.; Yan, O.; Jiang, L.; Wang, W.; Cao, D.; Zhao, C.

10.1101/2024.08.23.609368 — cancer biology — Posted on 2024-08-26

1007 Diarylamidine activation of a brachiopod DEG/ENaC/ASIC channel

Marti-Solans, J.; Borve, A.; Hejnol, A.; Lynagh, T.

10.1101/2024.08.26.609674 — biophysics — Posted on 2024-08-26

1008 Substrate stress relaxation regulates monolayer fluidity and leader cell formation for collectively migrating epithelia.

Charbonier, F. W.; Zhu, J.; Slyman, R.; Allan, C.; Chaudhuri, O.

10.1101/2024.08.26.609529 — biophysics — Posted on 2024-08-26

1009 BioLP-bench: Measuring understanding of AI models of biological lab protocols

Ivanov, I.

10.1101/2024.08.21.608694 — bioinformatics — Posted on 2024-08-26

1010 StrIDR: a database of intrinsically disordered regions of proteins with experimentally resolved structures

Majila, K.; Viswanath, S.

10.1101/2024.08.22.609111 — bioinformatics — Posted on 2024-08-26

1011 Proteome structuring of crown-of-thorns starfish

Zhu, Y.; Lu, Z.

10.1101/2024.08.25.609624 — bioinformatics — Posted on 2024-08-26

1012 Dissecting heterogeneity of tumor microenvironment in colorectal cancer using high-resolution single-cell atlas

Marteau, V.; Nemati, N.; Handler, K.; Raju, D.; Soto, E. K.; Fotakis, G.; Carollo, S.; Boeck, N.; Kirchmair, A.; Scheiber, A.; Ammann, A.; Seeber, A.; Gasser, E.; Horvath, L.; Fazilaty, H.; Valenta, T.; Sturm, G.; Rieder, D.; Sopper, S.; Pircher, A.; Ziegler, P.; Tschurtschenthaler, M.; Wolf, D.; Arnold, I.; Salcher, S.; Trajanoski, Z.

10.1101/2024.08.26.609563 — bioinformatics — Posted on 2024-08-26

1013 Data-guided direct reprogramming of human fibroblasts into the hematopoietic lineage

Stansbury, C.; Cwycyshyn, J.; Pickard, J.; Meixner, W.; Rajapakse, I.; Muir, L. A.

10.1101/2024.08.26.609589 — bioinformatics — Posted on 2024-08-26

1014 funkea: Functional Enrichment Analysis in Python

Tenmann, B.; Close, K.; Rodriguez-Martinez, A.; Abujudeh, S.

10.1101/2024.08.24.609502 — bioinformatics — Posted on 2024-08-26

1015 Cluster Buster: A Machine Learning Algorithm for Genotyping SNPs from Raw Data

Martin, J. L.; Kuznetsov, N.; Levine, K.; Koretsky, M.; Hong, S.; Vitale, D.; Nalls, M. A.

10.1101/2024.08.23.609429 — bioinformatics — Posted on 2024-08-26

1016 Vasculature segmentation in 3D hierarchical phase-contrast tomography images of human kidneys

Jain, Y.; Walsh, C. L.; Yagis, E.; Aslani, S.; Nandanwar, S.; Zhou, Y.; Ha, J.; Gustilo, K. S.; Brunet, J.; Rahmani, S.; Tafforeau, P.; Bellier, A.; Weber, G. M.; Lee, P. D.; Borner, K.

10.1101/2024.08.25.609595 — bioinformatics — Posted on 2024-08-26

1017 PhyloMix: Enhancing microbiome-trait association prediction through phylogeny-mixing augmentation

Jiang, Y.; Liao, D.; Zhu, Q.; Lu, Y.

10.1101/2024.08.26.609661 — bioinformatics — Posted on 2024-08-26

1018 AI-based Prediction of Protein Corona Composition on DNA Nanostructures

Huzar, J.; Coreas, R.; Landry, M. P.; Tikhomirov, G.

10.1101/2024.08.25.609594 — bioengineering — Posted on 2024-08-26

1019 Proteolysis targeting chimera extracellular vesicles for therapeutic development treating triple negative breast cancer

Erwin, N.; De, U.; Xiao, Y.; Wang, L.; Maharjan, C.; Pan, X.; Awasthee, N.; Zheng, G.; Liao, D.; Zhang, W.; He, M.

10.1101/2024.08.25.609564 — bioengineering — Posted on 2024-08-26

1020 Rapid selection of transgenic mammalian cells via diphtheria toxin resistance

Scherer, D.; Honrath, S.; Leroux, J.-C.; Burger, M.

10.1101/2024.08.26.609662 — bioengineering — Posted on 2024-08-26

1021 Predictive Dynamic Control Accurately Maps the Design Space for 2,3-Butanediol Production

Gotsmy, M.; Erian, A.; Marx, H.; Pfluegl, S.; Zanghellini, J.

10.1101/2024.08.26.609681 — bioengineering — Posted on 2024-08-26

1022 Odor source localization behavior of an insect enhanced by intermittent intake strategy

Shigaki, S.; Matsushita, T.; Ohashi, H.; Ando, N.; Hosoda, K.

10.1101/2024.08.26.609633 — animal behavior and cognition — Posted on 2024-08-26

1023 Playtime for Cephalopods: Understanding the Significance of Play Behavior inOctopus bimaculoides

Jarmoluk, K.; Pelled, G.

10.1101/2024.08.23.609397 — animal behavior and cognition — Posted on 2024-08-26

1024 Habitat partitioning and spatial segregation at multiple scales promotes year-round coexistence in a guild of forest songbirds

Berlusconi, A.; Castiglione, G.; Wauters, L. A.; Martinoli, A.; Clerici, E.; Mologni, A.; Morganti, M.; Martinoli, A.; Romano, A.; Rubolini, D.

10.1101/2024.08.26.609673 — animal behavior and cognition — Posted on 2024-08-26

1025 Variation in diel timing in great tits is affected by the timing of their social mate

Strauss, A. F. T.; Tomotani, B. M.; Visser, M. E.; Helm, B.

10.1101/2024.08.26.609680 — animal behavior and cognition — Posted on 2024-08-26

1026 Genomic signatures and demographic history of the widespread and critically endangered yellow-breasted bunting

Chen, G.; Sin, S. Y. W.

10.1101/2024.08.26.609693 — genomics — Posted on 2024-08-26

1027 Improved genetic discovery and fine-mapping resolution through multivariate latent factor analysis of high-dimensional traits

Zhou, F.; Astle, W. J.; Butterworth, A. S.; Asimit, J. L.

10.1101/2024.08.23.609452 — genetics — Posted on 2024-08-26

1028 Declining juvenile survival of Adelie penguins in Antarctica

Barracho, T.; Bardon, G.; Choquet, R.; Houstin, A.; Winterl, A.; Beaulieu, M.; Blanchard, P.; Cornet, C. C.; Cristofari, R.; Raclot, T.; Richter, S.; Chatelain, N.; Courtecuisse, J.; Brucker, M.; Zitterbart, D. P.; Lecomte, N.; Le Bohec, C.

10.1101/2024.08.23.609289 — ecology — Posted on 2024-08-26

1029 Rough Grouping Enhances YOLO's Pollinator Classification and Detection from Small Datasets

Kim, S.

10.1101/2024.08.24.609510 — ecology — Posted on 2024-08-26

1030 Extinction probabilities of small structured populations: adequate short-term model predictions in Folsomia candida

Van Dooren, T. J.; Haccou, P.; Tully, T.; Hermus, G.

10.1101/2024.08.26.609669 — ecology — Posted on 2024-08-26

1031 Mitochondrial activity-driven hematopoietic stem cell fate and lympho-myeloid lineage choice is first established in the aorta-gonad-mesonephros

Prakash, A.; Inamdar, M. S.

10.1101/2024.08.25.609550 — developmental biology — Posted on 2024-08-26

1032 Cell cycle re-entry in the aging Drosophila brain.

Damschroder, D.; Sun, J.; McDonald, K. O.; Buttitta, L.

10.1101/2024.08.26.609689 — developmental biology — Posted on 2024-08-26

1033 c-Abl Kinase Targets Tight Junction Protein ZO-2 in Regulation of Cell Migration and Morphology

Choi, D. E.; Gweon, B.; Notbohm, J.; Liu, X.-S.; Fredberg, J. J.

10.1101/2024.08.25.609487 — cell biology — Posted on 2024-08-26

1034 MED26-enriched condensates drive erythropoiesis through modulating transcription pausing

Zhu, S.; Zhang, X.; Li, N.; Zhao, X.; Li, M.; Xie, S.; Yue, Q.; Li, Y.; Li, D.; Wu, F.; Zhang, Z.; Feng, Z.; Zhang, Y.; Choi, W.; Jia, X.; Deng, Y.; Hu, Q.; Yao, X.; Gao, X.; Lee, H.-Y. S.

10.1101/2024.08.26.609654 — cell biology — Posted on 2024-08-26

1035 Integrating microscopy and transcriptomics from individual uncultured eukaryotic plankton

Gatt, C. R.; Xie, Y.; Wahi, K.; Johansson Beves, E.; Zanini, F.

10.1101/2024.08.25.609620 — microbiology — Posted on 2024-08-26

1036 Cell wall arabinogalactan is responsible for Fungitell(R) cross reactivity in nocardiosis

Mariller, C.; Letowski, P.; Chang, W.-T.; Lowary, T.; Ulrich, M.; Faure, K.; Loridant, S.; Sendid, B.; Wallet, F.; Poulain, D.; Hazzan, M.; Frimat, M.; Guerardel, Y.; Titecat, M.

10.1101/2024.08.22.608962 — microbiology — Posted on 2024-08-26

1037 Withaferin A reduces pulmonary eosinophilia and IL-25 production in a mouse model of allergic airways disease

Agner, K.; McQuade, V. L.; Womble, J.; Guttenberg, M. A.; Phatak, S.; Ingram, J. L.

10.1101/2024.08.26.609636 — immunology — Posted on 2024-08-26

1038 Exploring the role of the rich club in network control of neurocognitive states

Podschun, A. N.; Betzel, R. F.; Braun, U.; Markett, S.

10.1101/2024.08.26.608239 — neuroscience — Posted on 2024-08-26

1039 Simultaneous GCaMP imaging and focal recording of tonic and phasic synapses: Probing short-term plasticity within a defined microenvironment

Xing, X.; Wu, C.-F.

10.1101/2024.08.25.609565 — neuroscience — Posted on 2024-08-26

1040 The role of protein shape in multiphasic separation within condensates

Pandey, V.; Hosokawa, T.; Hayashi, Y.; Urakubo, H.

10.1101/2024.08.26.606306 — neuroscience — Posted on 2024-08-26

1041 Intra-individual variability in the effects of transcranial directcurrent stimulation on free choice saccade behaviour

Caie, B.; Blohm, G.

10.1101/2024.08.23.609379 — neuroscience — Posted on 2024-08-26

1042 Perception/action coupling in children with autism: insights from looking time and pupil dilation measurements

Clavaud-Seon, N.; Guillon, Q.; Vergne, J.; Sonie, S.; Schmitz, C.

10.1101/2024.08.22.609181 — neuroscience — Posted on 2024-08-26

1043 Industrializing yeast as a drug repurposing platform for inherited metabolic diseases

Thevandavakkam, M. A.; Long, N. E.; Roel, B. M.; Kantautas, K. A.; Zakin, S.; Duesterberg, V.; Perlstein, E. O.

10.1101/2024.08.23.609415 — systems biology — Posted on 2024-08-26

1044 Improvement of Spontaneous Locomotor Activity in a Murine Model of Duchenne Muscular Dystrophy by N-Acetylglucosamine Alone and in Combination with Prednisolone

Satoh, M. S.; St-Pierre, G.; Rancourt, A.; Fillion, M.; Sato, S.

10.1101/2024.08.25.609562 — physiology — Posted on 2024-08-26

1045 The potential role of taurine in acetaminophen hepatotoxic induced rats

Babalola, I. O.; Adekunle, H. K.; Adigun, M. D.

10.1101/2024.08.23.609394 — physiology — Posted on 2024-08-26

1046 An Affordable and Customizable Arduino-based Thermo-controller for Thermal Ecology Experiments

Hawk, C.; Iverson, E.; Havird, J. C.

10.1101/2024.08.23.609058 — physiology — Posted on 2024-08-26

1047 Disruption of ultrasonic vocalization with systemic administration of the non-competitive N-methyl-d-aspartate receptor antagonist MK-801 in adult male mice

Tamura, R.; Ujihara, Y.; Yamamoto, M.; Matsushima, S.; Kasahara, H.; Nasukawa, D.; Hayashi, K.; Yamada, K.; Tanaka, M.; Toda, K.

10.1101/2024.08.25.609588 — pharmacology and toxicology — Posted on 2024-08-26

1048 Widespread Neuroanatomical Integration and Distinct Electrophysiological Properties of Glioma-Innervating Neurons

Hsieh, A. L.; Ganesh, S.; Kula, T.; Irshad, M.; Ferenczi, E. A.; Wang, W.; Chen, Y.-C.; Hu, S.-H.; Li, Z.; Joshi, S.; Haigis, M. C.; Sabatini, B. L.

10.1101/2024.08.25.609573 — cancer biology — Posted on 2024-08-26

1049 Discovery of Novel, Potent and Orally Bioavailable SMARCA2 PROTACs with Synergistic Anti-tumor Activity in Combination with KRAS G12C Inhibitors.

Kotagiri, S. k.; Wang, Y.; Han, Y. Y.; Liang, X.; Blazanin, N.; Nguyen, P. K.; Jiang, Y.; Lissanu, Y.

10.1101/2024.08.23.608456 — cancer biology — Posted on 2024-08-26

1050 A systematic evaluation of highly variable gene selection methods for single-cell RNA-sequencing

Zhao, R.; Lu, J.; Zhou, W.; Zhao, N.; Ji, H.

10.1101/2024.08.25.608519 — bioinformatics — Posted on 2024-08-26

1051 Spatial model of cell-fate choice uncovers strong links between tissue morphology and tissue regeneration

Mani, S.; Tlusty, T.

10.1101/2024.08.25.609579 — developmental biology — Posted on 2024-08-26

1052 NOTCH-driven oscillations control cell fate decisions during intestinal homeostasis

Weterings, S. D. C.; Eto, H.; de Leede, J.-D.; Giladi, A.; Hoekstra, M. E.; Beijk, W.; Liefting, E. J. M.; van den Anker, K. B.; van Rheenen, J.; van Oudenaarden, A.; Sonnen, K. F.

10.1101/2024.08.26.609553 — cell biology — Posted on 2024-08-26

1053 N-Acetylglucosamine Facilitates Coordinated Myoblast Flow, Forming the Foundation for Efficient Myogenesis

Satoh, M. S.; Rancort, A.; St-Pierre, G.; Bouchard, E.; Fillion, M.; Hagiwara, K.; Nakajima, K.; Sato, S.

10.1101/2024.08.25.609576 — cell biology — Posted on 2024-08-26

1054 A Tale of Two Environments: Divisive Normalization and the (In)Flexibility of Choice

Kurtz David, V.; Sinha, S.; Alladi, V.; Bucher, S.; Brandenburger, A.; Louie, K.; Glimcher, P.; Tymula, A.

10.1101/2024.08.25.609561 — neuroscience — Posted on 2024-08-26

1055 Repetitive neonatal pain increases spinal cord DNA methylation of the μ-opioid receptor

Baudat, M.; Joosten, E. A. J.; Simons, S. H. P.; van den Hove, D. L. A.; Riemens, R. J. M.

10.1101/2024.08.25.609598 — neuroscience — Posted on 2024-08-26

1056 Meisoindigo: An Effective Inhibitor of SARS-CoV-2 Main Protease Revealed by Yeast System

Grabinski, W.; Kicinska, A.; Kosicka, E.; Baranek-Grabinska, M.; Hejenkowska, E. D.; Budzik, J.; Sliska, P.; Sliwinska, W.; Karachitos, A.

10.1101/2023.09.03.555867 — pharmacology and toxicology — Posted on 2024-08-26

1057 Variations and predictability of epistasis on an intragenic fitness landscape.

Baheti, S.; Raj, N.; Saini, S.

10.1101/2024.08.25.609583 — evolutionary biology — Posted on 2024-08-26

1058 Metastable Dynamics Emerge from Local Excitatory-Inhibitory Homeostasis in the Cortex at Rest

Pascoa dos Santos, F.; Verschure, P. F.

10.1101/2024.08.24.609501 — neuroscience — Posted on 2024-08-26

1059 Pictorial balance is a bottom-up neuro-aesthetic property mediating attention and eye movements. A model of a primitive visual operating system explains the property of balance and some visual properties of pictures

Corwin, D. M.

10.1101/2020.05.26.104687 — neuroscience — Posted on 2024-08-26

1060 Evolution of the Spatial transcriptomic landscape during the progression of high-grade pancreatic intraductal papillary mucinous neoplasms to invasive cancer

Peng, S.; Chen, Q.; Chen, Z.; Yao, M.; Cai, Y.; He, D.; Cai, Y.; Cheng, K.; Li, J.; Cai, H.; Gao, P.; Gu, X.; Wang, X.; Li, Y.; Zhang, M.; Meng, L.; Xia, Q.; Xu, P.; Zhou, J.; Wu, Z.; Peng, B.

10.1101/2024.08.24.608470 — cancer biology — Posted on 2024-08-26

1061 E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model.

Sayed, I. M.; Chakraborty, A.; Inouye, K.; Dugan, L.; Tocci, S.; Advani, I.; Park, K.; Hazra, T. K.; Das, S.; Crotty Alexander, L. E.

10.1101/2024.08.23.609469 — cancer biology — Posted on 2024-08-26

1062 Single-molecule diffusivity quantification in Xenopus egg extracts elucidates physicochemical properties of the cytoplasm

Choi, A.; Zhou, C. Y.; Tabo, A.; Heald, R.; Xu, K.

10.1101/2024.08.24.609541 — biophysics — Posted on 2024-08-26

1063 MuLAN: Mutation-driven Light Attention Networks for investigating protein-protein interactions from sequences

Lombardi, G.; Carbone, A.

10.1101/2024.08.24.609515 — bioinformatics — Posted on 2024-08-26

1064 Developing and characterising decellularized extracellular matrix hydrogels to bio-fabricate female reproductive tissues

Ribes Martinez, E.; Franko, Y.; Franko, R.; Ferronato, G.; Viana, A.; Windenbach, E.; Stoeckl, J.; Frolich, T.; de Almeida Monteiro Melo Ferraz, M.

10.1101/2024.08.24.609513 — bioengineering — Posted on 2024-08-26

1065 Integration of parallel pathways for flight control in a hawkmoth reflects prevalence and relevance of natural visual cues

Stoeckl, A.; Bigge, R.; Grittner, R.

10.1101/2024.08.24.609346 — animal behavior and cognition — Posted on 2024-08-26

1066 Functional traits and soil water availability shape competitive interactions in a diploid-polyploid complex

Rodriguez-Parra, A.; Lopez-Jurado, J.; Mateos Naranjo, E.; Balao, F.

10.1101/2024.08.23.608238 — ecology — Posted on 2024-08-26

1067 GeneDrive.jl: A decision tool to optimize vector-borne disease management planning under climate change

Vasquez, V. N.; Mordecai, E. A.; Anthoff, D.

10.1101/2024.08.23.609480 — ecology — Posted on 2024-08-26

1068 ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability

Tambrin, H. M.; Liu, Y.; Zhu, K.; Teng, X.; Toyama, Y.; Miao, Y.; Ludwig, A.

10.1101/2024.08.24.609485 — cell biology — Posted on 2024-08-26

1069 NeuroAtlas: An Artificial Intelligence-based Framework for Annotation, Segmentation and Registration of Large Scale Biomedical Imaging Data

Mahmood, H.; Nawar, F.; Islam, S. M. S.; Iqbal, A.

10.1101/2024.08.24.609507 — neuroscience — Posted on 2024-08-26

1070 Validating genuine changes in Heartbeat Evoked Potentials using Pseudotrials and Surrogate Procedures

Steinfath, T. P. P.; Herzog, N.; Fourcade, A.; Sander, C.; Nikulin, V.; Villringer, A.

10.1101/2024.08.24.609348 — neuroscience — Posted on 2024-08-26

1071 Segment AnyNeuron

Razzaq, T.; Qazi, A.; Iqbal, A.

10.1101/2024.08.24.609505 — neuroscience — Posted on 2024-08-26

1072 Structural and functional dissection of the Pacinian corpuscle reveals an active role of the inner core in touch detection

Ziolkowski, L. H.; Nikolaev, Y. A.; Chikamoto, A.; Oda, M.; Feketa, V. V.; Monedero-Alonso, D.; Ardasheva, S. A.; Bae, S. S.; Xu, C. S.; Pang, S.; Gracheva, E. O.; Bagriantsev, S. N.

10.1101/2024.08.24.609509 — neuroscience — Posted on 2024-08-26

1073 Chronic intermittent alcohol yields sex-specific disruptions in cortical-striatal-limbic oscillations

Hewitt, K.; Nicholson, S.; Peterson, M.; Dwiel, L.; Henricks, A. M.

10.1101/2024.08.23.609453 — neuroscience — Posted on 2024-08-26

1074 Glymphatic clearance is enhanced during sleep

Kroesbergen, E.; Riesselmann, L. V.; Gomolka, R. S.; Pla, V.; Esmail, T.; Stenmo, V. H.; Kovacs, E. R.; Nielsen, E. S.; Goldman, S. A.; Nedergaard, M.; Weikop, P.; Mori, Y.

10.1101/2024.08.24.609514 — neuroscience — Posted on 2024-08-26

1075 SynPull: a novel method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy

Kedia, S.; Fertan, E.; Wu, Y.; Zhang, Y. P.; Meisl, G.; Lam, J. Y. L.; Wiseman, F. K.; McEwan, W. A.; Quaegebeur, A.; Spillantini, M. G.; Danial, J.; Klenerman, D.

10.1101/2024.08.24.609517 — neuroscience — Posted on 2024-08-26

1076 Stepwise Bayesian Machine Learning Uncovers a Novel Gene Regulatory Network Component in Neural Tube Development

Xing, C.; Sakumura, Y.; Kokaji, T.; Kunida, K.; Sasai, N.

10.1101/2024.08.25.609396 — systems biology — Posted on 2024-08-26

1077 BCL2L13 Influences Autophagy and Ceramide Metabolism without Affecting Temozolomide Resistance in Glioblastoma

Clark, C.; Barzegar Behrooz, A.; Da Silva Rosa, S. C.; Jacobs, J.; Weng, X.; Srivastava, A.; Vitorino, R.; Ande, S. R.; Ravandi, A.; Dhingra, S.; Pecic, S.; Miller, D.; Shojaei, S.; Ghavami, S.

10.1101/2024.08.23.609447 — cancer biology — Posted on 2024-08-26

1078 A forward genetic screen identifies Sirtuin1 as a driver of neuroendocrine prostate cancer

Nunes de Almeida, F.; Vasciaveo, A.; Antao, A. M.; Zou, M.; Di Bernardo, M.; de Brot, S.; Rodriguez-Calero, A.; Chui, A.; Wang, A. L. E.; Floch, N.; Kim, J. Y.; Afari, S. N.; Mukhammadov, T.; Arriaga, J. M.; Lu, J.; Shen, M. M.; Rubin, M.; Califano, A.; Abate-Shen, C.

10.1101/2024.08.24.609538 — cancer biology — Posted on 2024-08-26

1079 AlphaFold2 knows some protein folding principles

Chang, L.; Perez, A.

10.1101/2024.08.25.609581 — biophysics — Posted on 2024-08-26

1080 msiFlow: Automated Workflows for Reproducible and Scalable Multimodal Mass Spectrometry Imaging and Immunofluorescence Microscopy Data Processing and Analysis

Spangenberg, P.; Bessler, S.; Widera, L.; Bottek, J.; Richter, M.; Thiebes, S.; Siemes, D.; Krauss, S.; Migas, L. G.; Kasarla, S. S.; Phapale, P.; Kleesiek, J.; Fuehrer, D.; Moeller, L. C.; Heuer, H.; Van de Plas, R.; Gunzer, M.; Soehnlein, O.; Soltwisch, J.; Shevchuk, O.; Dreisewerd, K.; Engel, D. R.

10.1101/2024.08.24.609403 — bioinformatics — Posted on 2024-08-26

1081 tombRaider - improved species and haplotype recovery from metabarcoding data through artefact and pseudogene exclusion.

Jeunen, G.-J.; Fernandes, K.; Dowle, E.; Kroos, G. C.; Mauvisseau, Q.; Torma, M.; Miller, A. K.; Lamare, M.; Gemmell, N.

10.1101/2024.08.23.609468 — bioinformatics — Posted on 2024-08-26

1082 An explainable graph neural network approach for integrating multi-omics data with prior knowledge to identify biomarkers from interacting biological domains.

Tripathy, R. K.; Frohock, Z.; Wang, H.; Cary, G. A.; Keegan, S.; Carter, G. W.; Li, Y.

10.1101/2024.08.23.609465 — bioinformatics — Posted on 2024-08-26

1083 CRISP: Correlation-Refined Image Segmentation Process

Briggs, J.; Jin, E.; Merrins, M. J.; Benninger, R. K.

10.1101/2024.08.23.609461 — bioengineering — Posted on 2024-08-26

1084 Evaluating the Efficacy of Serum-Free Media Supplemented with Protein Isolates for Bovine Satellite Cell Proliferation: A Sustainable Approach for Cultivated Meat Production

Amirvaresi, A.; Ovissipour, R.

10.1101/2024.08.23.609451 — bioengineering — Posted on 2024-08-26

1085 Ecosystem stability relies on diversity difference between trophic levels

Liu, Y.; Hu, J.; Gore, J.

10.1101/2024.08.23.609466 — ecology — Posted on 2024-08-26

1086 Canonical Wnt signalling from the Area Opaca induces and maintains the Marginal Zone in pre-primitive-streak stage chick embryos

Fadaili, Y.; Lu, H.-C.; Lee, H. C.; Stern, C. D.

10.1101/2024.08.24.609497 — developmental biology — Posted on 2024-08-26

1087 A genetically encoded fluorescent reporter for polyamines

Sharma, P.; Kim, C. Y.; Keys, H. R.; Imada, S.; Joseph, A. B.; Ferro, L.; Kunchok, T.; Anderson, R.; Yilmaz, O. H.; Weng, J.-K.; Jain, A.

10.1101/2024.08.24.609500 — cell biology — Posted on 2024-08-26

1088 Dynamic alterations of dural and bone marrow B cells in an animal model of progressive multiple sclerosis

Florescu, A.; Zuo, M.; Wang, A. A.; Champagne-Jorgensen, K.; Noor, M. A.; Ward, L. A.; van Puijenbroek, E.; Klein, C.; Gommerman, J.

10.1101/2024.08.23.609437 — immunology — Posted on 2024-08-26

1089 Assembly and performance of a cholera RDT prototype that detects both Vibrio cholerae and associated bacteriophage as a proxy for pathogen detection

SAYEED, M. A.; Nabil, I. K.; Bhattacharjee, P.; Hossain, M. S.; Akter, N. J.; Akter, R.; Kelley, K. L.; Karim, M.; Begum, Y. A.; Bhuiyan, T. R.; Qadri, F.; Khan, A. I.; Nelson, E. J.

10.1101/2024.08.23.609438 — immunology — Posted on 2024-08-26

1090 Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception

Chen, Y.-T.; de Thomas Wagner, D.; Loutit, A. J.; Nourizonoz, A.; Croisier-Coeytaux, M.-C.; Blanc, J.; Knott, G.; Lee, K.-S.; Huber, D.

10.1101/2024.08.23.609459 — neuroscience — Posted on 2024-08-26

1091 Neurons as biosensors for discriminating neurological disorders in a brain-on-chip platform: Application to Alzheimer s Disease using patient CSF

Miny, L.; Rontard, J.; Allouche, A.; Violle, N.; Dubuisson, L.; Batut, A.; Ponomarenko, A.; Talbi, R.; Gautier, H.; Maisonneuve, B.; Roux, S.; Larramendy, F.; Honegger, T.; Quadrio, I.

10.1101/2024.08.23.609425 — neuroscience — Posted on 2024-08-26

1092 Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila

Li, J.; Dhaliwal, R.; Stanley, M.; Junca, P.; Gordon, M. D.

10.1101/2024.08.23.609242 — neuroscience — Posted on 2024-08-26

1093 Amyloid-β deposition in basal frontotemporal cortex is associated with selective disruption of temporal mnemonic discrimination

Vanderlip, C.; Taylor, L.; Kim, S.; Harris, A. L.; Tuteja, N.; Meza, N.; Escalante, Y. Y.; McMillan, L.; Yassa, M. A.; Adams, J. N.

10.1101/2024.08.23.609449 — neuroscience — Posted on 2024-08-26

1094 Ischemic lesions to inferior frontal cortex alter the dynamics of conscious visual perception

Fritsch, M.; Michely, J.; Jaeckel, L.; Rangus, I.; Riegler, C.; Scheitz, J.; Nolte, C. H.; Sterzer, P.; Weilnhammer, V.

10.1101/2024.08.24.609496 — neuroscience — Posted on 2024-08-26

1095 Multimodal 3D Image Registration for Mapping Brain Disorders

Mahmood, H.; Islam, S. M. S.; Iqbal, A.

10.1101/2024.08.24.609508 — neuroscience — Posted on 2024-08-26

1096 Optimization of Seizure Prevention by Cannabidiol (CBD)

Bhandari, B.; Emami Naeini, S.; Rezaei, S.; Rogers, H. M.; Khodadadi, H.; Bosomtwi, A.; Seyyedi, M.; MacKinnon, N. J.; Dhandapani, K. M.; Lopes Salles, E.; Hess, D. C.; Yu, J. C.; Moore-Hill, D.; Vale, F. L.; Wang, L. P.; Baban, B.

10.1101/2024.08.24.609518 — neuroscience — Posted on 2024-08-26

1097 Optimizing real-time phase detection in diverse rhythmic biological signals for phase-specificneuromodulation

Liufu, M.; Leveroni, Z. M.; Shridhar, S.; Zhou, N.; Yu, J. Y.

10.1101/2024.08.24.609522 — neuroscience — Posted on 2024-08-26

1098 Longitudinally cultured precision cut lung slices as a predictive ex vivo model for lung cancer

Sargsian, A.; Girmatsion, H.; Lenders, V.; Ghesquiere, B.; Takeno Cologna, C.; Soenen, S. J.; Manshian, B. B.

10.1101/2024.08.23.609442 — cancer biology — Posted on 2024-08-26

1099 TUMOR-INFILTRATING NOCICEPTOR NEURONS PROMOTE IMMUNOSUPPRESSION

Restaino, A. C.; Ahmadi, M.; Nikpoor, A. R.; Walz, A.; Balood, M.; Eichwald, T.; Talbot, S.; Vermeer, P. D.

10.1101/2024.08.23.609450 — cancer biology — Posted on 2024-08-26

1100 Statins attenuate Wnt/β-catenin signaling by targeting SATB family proteins in colorectal cancer

Tripathi, S.; Gupta, E.; Naik, R.; Khare, S.; Mir, R.; Yadav, S.; Desai, S.; Humane, S.; Bal, M.; Saklani, A.; Patil, P.; Kamat, S.; Galande, S.

10.1101/2024.08.23.609189 — cancer biology — Posted on 2024-08-26

1101 Spatio-temporal segmentation of contraction waves in the extra-embryonic membranes of the red flour beetle

Pereyra, M.; Golden, M.; Lange, Z.; Golden, A.; Strobl, F.; Stelzer, E. H. K.; Matthaeus, F.

10.1101/2024.08.23.609389 — bioinformatics — Posted on 2024-08-26

1102 Using dynamic ultrasound to assess Achilles tendon mechanics during running: the effect on running pattern and muscle-tendon junction tracking

Schallig, W.; Sloot, Y.; van der Schaaf, M. M.; Bus, S. A.

10.1101/2024.08.23.609380 — bioengineering — Posted on 2024-08-26

1103 Functional high capacity exosome-encapsulating bioinspired hydrogel promotes microvascularbed expansion in diabetic mice

Subhan, B. S.; Cortes Troncoso, J. F.; Katyal, P.; Meleties, M.; Mestvirishvili, T.; Arias, F.; Wang, A.; Ruggles, K.; Dolgalev, I.; Mita, P.; Montclare, J. K.; Rabbani, P. S.

10.1101/2024.08.23.609402 — bioengineering — Posted on 2024-08-26

1104 Listening to the bats of Carajás: Applied bioacoustics for species inventory and environment use in a mosaic of forests, savannas, and industrial mining in the Brazilian Amazonia

Gomes, L.; BERNARD, E.

10.1101/2024.08.23.609443 — ecology — Posted on 2024-08-26

1105 Reduction of SEM charging artefacts in native cryogenic biological samples.

Velazco, A.; Glen, T.; Klumpe, S.; Pennington, A.; Zhang, J.; Smith, J. L.; Glynn, C.; Bowles, W.; Kobylynska, M.; Fleck, R. A.; Naismith, J. H.; Kim, J. S.; Darrow, M. C.; Grange, M.; Kirkland, A. I.; Dumoux, M.

10.1101/2024.08.23.609373 — cell biology — Posted on 2024-08-26

1106 Unlocking new avenues for non-invasive brain monitoring with combined electroencephalography and functional magnetic resonance imaging at ultra-high field

Sainz Martinez, C.; Wirsich, J.; Jager, C.; Warbrick, T.; Vulliemoz, S.; Lemay, M.; Bastiaansen, J.; Wiest, R.; Jorge, J.

10.1101/2024.08.23.609301 — neuroscience — Posted on 2024-08-26

1107 Population coding under the scale-invariance of high-dimensional noise

Moosavi, S. A.; Hindupur, S. S. R.; Shimazaki, H.

10.1101/2024.08.23.608710 — neuroscience — Posted on 2024-08-26

1108 Therapeutically targeting the classical complement pathway with antisense oligonucleotides in Alzheimer's disease

Wang, Y.; Wu, T.; Gogineni, A.; Tsai, M.-C.; Kielpinski, L.; Mahajan, A.; Pandey, S.; Schachner, L.; Tran, J. C.; Wu, C.; Schauer, S.; Biever, A.; Boesen, S.; Li, M.; Munk, A.; Meilandt, W. J.; Elstrott, J.; Easton, A.; Gylling, H. M.; Hanson, J. E.

10.1101/2024.08.23.609240 — neuroscience — Posted on 2024-08-26

1109 Mechanistic modeling of cell viability assays with in silico lineage tracing

Mutsuddy, A.; Huggins, J. R.; Amrit, A.; Erdem, C.; Calhoun, J. C.; Birtwistle, M. R.

10.1101/2024.08.23.609433 — systems biology — Posted on 2024-08-26

1110 Increased Postprandial Metabolic Flexibility is Associated with Higher Body Fat Percentages in Healthy Young Adults

Foreman, N. A.; Rajwade, S.; Bluth, J.; Skoglund, L.; Letts, A. M.; DiPietro, L.; Ciarleglio, A.; Barberio, M.

10.1101/2024.08.23.609405 — physiology — Posted on 2024-08-26

1111 A tactile discrimination task to study neuronal dynamics in freely-moving mice

Heimburg, F.; Mari Saluti, N.; Timm, J.; Adlakha, A.; Castelanelli, M.; Klumpp, M.; Embray, L.; Both, M.; Draguhn, A.; Kuner, T.; Groh, A.

10.1101/2024.08.24.609326 — neuroscience — Posted on 2024-08-26

1112 Movement-independent representation of reward-predicting cues in the medial part of the primate premotor cortex

Sehara, K.; Kondo, M.; Hirayama, Y.; Ebina, T.; Takaji, M.; Watakabe, A.; Inoue, K.-i.; Takada, M.; Yamamori, T.; Matsuzaki, M.

10.1101/2024.08.24.609512 — neuroscience — Posted on 2024-08-26

1113 Medial Entorhinal VIP-expressing interneurons receive direct input from Anterior Dorsal Thalamus and are critical for spatial memory

Oule, M.; Badrinarayanan, S.; Sundar-Maccagno, R.; Brandon, M. P.

10.1101/2024.08.26.609578 — neuroscience — Posted on 2024-08-26

1114 Diurnal rhythms in durum wheat triggered by Rhopalosiphum padi (bird cherry-oat aphid)

Goldstein, Y.; Han, J.; Kunk, D.; Batushansky, A.; Nalam, V. J.; Tzin, V.

10.1101/2024.08.25.609566 — plant biology — Posted on 2024-08-26

1115 eGADA: enhanced Genomic Alteration Detection Algorithm, a fast genomic segmentation algorithm based on Sparse Bayesian Learning

Huang, Y. S.

10.1101/2023.08.20.553622 — bioinformatics — Posted on 2024-08-26

1116 The Role of Sex in Atherosclerotic Inflammation and Lipid-Handling Dysfunction

Liu, P. Z.; Zhang, L. N.; Matz, A. J.

10.1101/2024.08.22.608101 — bioinformatics — Posted on 2024-08-26

1117 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

Rebollo, R.; Gerenton, P.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.

10.1101/2023.05.27.542554 — bioinformatics — Posted on 2024-08-26

1118 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.

Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; Tanmoy, A.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Astbury, S.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.

10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-26

1119 The genetic architecture of cell-type-specific cis-regulation

Marand, A. P.; Jiang, L.; Gomez-Cano, F. A.; Minow, M. A. A.; Zhang, X.; Mendieta, J. P.; Luo, Z.; Bang, S.; Yan, H.; Meyer, C.; Schlegel, L.; Johannes, F.; Schmitz, R. J.

10.1101/2024.08.17.608383 — genetics — Posted on 2024-08-26

1120 Cellular evolution of the hypothalamic preoptic area of behaviorally divergent deer mice

Chen, J.; Richardson, P. R.; Kirby, C.; Eddy, S. R.; Hoekstra, H.

10.1101/2024.08.22.608850 — evolutionary biology — Posted on 2024-08-26

1121 Estimation of Species Abundance Based on the Number of Segregating Sites using Environmental DNA (eDNA)

Ai, Q.; Yuan, H.; Wang, Y.; Li, C.

10.1101/2024.04.15.589638 — ecology — Posted on 2024-08-26

1122 Spatial Dynamics of the Developing Human Heart

10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-08-26

1123 Plasma triacylglycerol length and saturation level mark healthy aging groups in humans

Li, W. L.; Schomakers, B. V.; Weeghel, M. v.; Grevendonk, L.; Vaz, F. M.; Salomons, G. S.; Schrauwen, P.; Hoeks, J.; Gao, A. W.; Houtkooper, R. H.; Janssens, G. E.

10.1101/2024.08.22.609162 — developmental biology — Posted on 2024-08-26

1124 Epsins oversee smooth muscle cell reprogramming by influencing master regulators KLF4 and OCT4.

Wang, B.; Cui, K.; Zhu, B.; Dong, Y.; Wang, D.; Singh, B.; Wu, H.; Li, K.; Eisa-Beygi, S.; Sun, Y.; Wong, S.; Cowan, D. B.; Chen, Y.; Du, M.; Chen, H.

10.1101/2024.01.08.574714 — cell biology — Posted on 2024-08-26

1125 G1 length dictates H3K27me3 landscapes

Trouth, A.; Ravichandran, K.; Gafken, P.; Martire, S.; Boyle, G. E.; Veronezi, G. M. B.; La, V.; Namciu, S. J.; Banaszynski, L. A.; Sarthy, J. F.; Ramachandran, S.

10.1101/2023.12.05.570186 — molecular biology — Posted on 2024-08-26

1126 Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

Ma, X.; Meng, L.; Zhang, Y.; Xu, T.; Zhou, X.; Qian, M.; Yang, Z.; Han, X.

10.1101/2023.10.02.560590 — microbiology — Posted on 2024-08-26

1127 Cell-type-specific striatal modulation of amygdalar acetylcholine in salience assignment

Chen, A.; Li, Y.; Zhu, H.; Gu, H.; Weng, Y.; Ye, Q.; Guan, W.; Sun, Q.; Li, B.; Xu, F.; Deng, H.; Xiao, X.

10.1101/2024.07.30.605919 — neuroscience — Posted on 2024-08-26

1128 Expertise in reading visual Braille co-opts the reading network

Cerpelloni, F.; Van Audenhaege, A.; Matuszewski, J.; Gau, R.; Battal, C.; Falagiarda, F.; Op de Beeck, H.; Collignon, O.

10.1101/2024.05.08.593104 — neuroscience — Posted on 2024-08-26

1129 Trial-by-trial detection of cognitive events in neural time-series

Weindel, G.; van Maanen, L.; Borst, J. P.

10.1101/2024.02.13.580102 — neuroscience — Posted on 2024-08-26

1130 Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity

Kim, G.; Kim, P.

10.1101/2024.08.16.608240 — neuroscience — Posted on 2024-08-26

1131 How distributed subcortical integration of reward and threat may inform approach-avoidance decisions

Hulsman, A. M.; Klaassen, F. H.; De Voogd, L. D.; Roelofs, K.; Klumpers, F.

10.1101/2024.04.22.590530 — neuroscience — Posted on 2024-08-26

1132 A new theoretical framework jointly explains behavioral and neural variability across subjects performing flexible decision-making

Pagan, M.; Tang, V. D.; Aoi, M. C.; Pillow, J. W.; Mante, V.; Sussillo, D.; Brody, C. D.

10.1101/2022.11.28.518207 — neuroscience — Posted on 2024-08-26

1133 SMC complex unidirectionally translocates DNA by coupling segment capture with an asymmetric kleisin path

Yamauchi, M.; Brandani, G. B.; Terakawa, T.; Takada, S.

10.1101/2024.04.29.591782 — biophysics — Posted on 2024-08-26

1134 BiRNA-BERT Allows Efficient RNA Language Modeling with Adaptive Tokenization

Tahmid, M. T.; Shahgir, H. S.; Mahbub, S.; Dong, Y.; Bayzid, M. S.

10.1101/2024.07.02.601703 — bioinformatics — Posted on 2024-08-26

1135 CIA: a Cluster Independent Annotation method to investigate cell identities in scRNA-seq data

Ferrari, I.; Battistella, M.; Vincenti, F.; Gobbini, A.; Marini, F.; Notarbartolo, S.; Costanza, J.; Biffo, S.; Grifantini, R. M.; Abrignani, S.; Galeota, E.

10.1101/2023.11.30.569382 — bioinformatics — Posted on 2024-08-26

1136 Basis of Glucose and Fructose Selectivity in Sugar Transport Proteins

Andersen, C. G.; Bavnhoj, L.; Brag, S.; Driller, J. H.; Pedersen, B. P.

10.1101/2024.07.19.604285 — biochemistry — Posted on 2024-08-26

1137 Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production

Borges, K. S.; Little, D.; de Almeida Magalhaes, T.; Ribeiro, C.; Dumontet, T.; Lapensee, C.; Basham, K. J.; Seth, A.; Azova, S.; Guagliardo, N. A.; Barret, P. Q.; Berber, M.; O'Connell, A. E.; Turcu, A. F.; Lerario, A. M.; Mohan, D.; Rainey, W.; Carlone, D. L.; Hirschhorn, J.; Salic, A.; Breault, D.; Hammer, G. D.

10.1101/2024.08.23.609423 — genetics — Posted on 2024-08-26

1138 Exploitation of phylum-spanning omics resources reveals complexity in the nematode FLP signalling system and provides insights into flp-gene evolution

McCoy, C. J.; Wray, C.; Freeman, L.; Crooks, B. A.; Golinelli, L.; Marks, N. J.; Temmerman, L.; Beets, I.; Atkinson, L. E.; Mousley, A.

10.1101/2024.08.25.609560 — evolutionary biology — Posted on 2024-08-26

1139 The Regulatory Logic of Planarian Stem Cell Differentiation

Perez-Posada, A.; Garcia-Castro, H.; Emili, E.; Vanni, V.; Arias-Baldrich, C.; Frölich, S.; van Heeringen, S. J.; Kenny, N. J.; Solana, J.

10.1101/2024.08.23.608747 — systems biology — Posted on 2024-08-26

1140 Predicting Alzheimer's Cognitive Resilience Score: A Comparative Study of Machine Learning Models Using RNA-seq Data

Kitani, A.; Matsui, Y.

10.1101/2024.08.25.609610 — bioinformatics — Posted on 2024-08-26

1141 Cellular and molecular networks of intercellular signaling in bone marrow hematopoiesis

Thomas, Z.; Wang, B.; Boohar, W.; Vergel, M.; Eerdeng, J.; Shon, D.; Elowitz, M. B.; Lu, R.

10.1101/2024.08.25.609544 — bioinformatics — Posted on 2024-08-26

1142 Bats from the Colombian Caribbean Reveal a new subtype of Influenza A (H18N12)

Echeverri, D. M.; Martinez-Bravo, C.; Gastelbondo-Pastrana, B.; Rivero, R. M.; Lopez, Y.; Hoyos, R.; Aleman, M.; Garay, E.; Bertel, V.; Arrieta, G.; Ramirez, J. D.; Mattar, S.

10.1101/2024.08.25.609627 — bioinformatics — Posted on 2024-08-26

1143 Benchmarking text-integrated protein language model embeddings and embedding fusion on diverse downstream tasks

Ko, Y. S.; Parkinson, J.; Wang, W.

10.1101/2024.08.24.609531 — bioinformatics — Posted on 2024-08-26

1144 Challenges in Detecting Somatic Recombination of Repeat Elements: Insights from Short and Long Read Datasets

Pascarella, G.; Frith, M. C.; Carninci, P.

10.1101/2024.08.25.609631 — genomics — Posted on 2024-08-26

1145 A link between aging and persistence

Proenca, A. M.; Rang, C. U.; Chao, L.

10.1101/2024.08.24.609520 — evolutionary biology — Posted on 2024-08-26

1146 Adaptation to yeast restriction through the evolution of resource acquisition, macronutrient reserve, and ovarian function

Dasgupta, P.; Koner, A.; Pal, R. S.; Pradhan, P. N.; Roychoudhury, K.; Nandy, B.

10.1101/2024.08.24.609539 — evolutionary biology — Posted on 2024-08-26

1147 The role of a non-native host plant in altering the seasonal dynamics of monarch development

DuBose, J. G.; Hoogshagen, M.; de Roode, J. C.

10.1101/2024.08.23.609406 — ecology — Posted on 2024-08-26

1148 Deciphering plant-beneficial fungal interactions: Unravelling metabolic diversity that underpins communication between Laccaria bicolor and Trichoderma

Sivaprakasam Padmanaban, P. B.; Stange, P.; Weber, B.; Ghirardo, A.; Pritsch, K.; Karl, T.; Benz, J. P.; Rosenkranz, M.; Schnitzler, J.-P.

10.1101/2024.08.26.608944 — microbiology — Posted on 2024-08-26

1149 mvh: an R tool to assemble and organize virtual herbaria from openly available specimen images

Vasconcelos, T.; Boyko, J.

10.1101/2024.08.25.609600 — plant biology — Posted on 2024-08-26

1150 Cholinergic basal forebrain neurons regulate vascular dynamics and cerebrospinal fluid flux

Chuang, K.-H.; Zhou, X. A.; Xia, Y.; Li, Z.; Qian, L.; Eeles, E.; Ngiam, G.; Fripp, J.; Coulson, E. J.

10.1101/2024.08.25.609536 — neuroscience — Posted on 2024-08-26

1151 Switch-like Gene Expression Modulates Disease Susceptibility

Aqil, A.; Li, Y.; Wang, Z.; Islam, S.; Russel, M.; Kunovac Kallak, T.; Saitou, M.; Gokcumen, O.; Masuda, N.

10.1101/2024.08.24.609537 — bioinformatics — Posted on 2024-08-26

1152 Mammalian retinal specializations for high acuity vision evolve in response to both foraging strategies and morphological constraints

Kopania, E. E. K.; Clark, N.

10.1101/2024.08.25.609608 — evolutionary biology — Posted on 2024-08-26

1153 A single-cell atlas of spatial and temporal gene expression in the mouse cranial neural plate

Brooks, E. R.; Moorman, A. R.; Bhattacharya, B.; Prudhomme, I.; Land, M.; Alcorn, H. L.; Sharma, R.; Pe'er, D.; Zallen, J. A.

10.1101/2024.08.25.609458 — developmental biology — Posted on 2024-08-26

1154 Fornix and Uncinate Fasciculus Support Metacognition-Driven Cognitive Offloading

Zheng, Y.; Bo, B.; Wang, D.; Liu, Y.; Gilbert, S. J.; Li, Y.; Kwok, S. C.

10.1101/2024.08.24.609527 — neuroscience — Posted on 2024-08-26

1155 Your Blood is Out for Delivery: Considerations of Shipping Time and Temperature on Degradation of RNA from Stabilized Whole Blood

Stefanovic, F.; Brown, L.; MacDonald, J.; Bammler, T. K.; Rinchai, D.; Nguyen, S.; Zeng, Y.; Shinkawa, V.; Adams, K.; Chaussabel, D.; Berthier, E.; Haack, A. J.; Theberge, A. B.

10.1101/2024.08.24.609519 — bioengineering — Posted on 2024-08-25

1156 SPACE: Spatially variable gene clustering adjusting for cell type effect for improved spatial domain detection.

Das Adhikari, S.; Steele, N. G.; Theisen, B.; Wang, J.; Cui, Y.

10.1101/2024.08.23.609477 — genomics — Posted on 2024-08-25

1157 Divergent macrophage induced lung pathology occurs between infants and adults during respiratory viral infection

Verhoeven, D.; Verhoeven, D.

10.1101/2024.08.25.609597 — immunology — Posted on 2024-08-25

1158 Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons

Topolski, M. A.; Gilmore, B. L.; Khondaker, R.; Michniak, J. A.; Studtmann, C.; Chen, Y.; Wagner, G. N.; Pozo-Aranda, A. E.; Farris, S.; Swanger, S. A.

10.1101/2024.08.23.607324 — neuroscience — Posted on 2024-08-25

1159 Universal features of Alternative splicing in response to diverse environmental stimuli in rice and the vital roles of TFs in AS regulation

Xiao, B.; Yang, S.; Wang, C.; Zhang, F.; Liu, Y.; Xiao, Z.; Xie, G.; Zhang, z.

10.1101/2024.08.23.609440 — plant biology — Posted on 2024-08-25

1160 Exploring symbiotic legume-rhizobia relationships across tropical species

Rojas-Jimenez, K.; Morera-Huertas, J.; de Bedout-Mora, M.; Loria-Vinueza, B.; Zuniga-Orozco, A.; Molina-Mora, J. A.; Solis-Ramos, L.; Blanco, M. A.; Valverde-Barrantes, O. J.

10.1101/2024.08.23.609460 — plant biology — Posted on 2024-08-25

1161 Title: Diurnal rhythms in durum wheat triggered by Rhopalosiphum padi (bird cherry-oat 2 aphid)

Goldstein, Y.; Han, J.; Kunk, D.; Batushansky, A.; Nalam, V. J.; Tzin, V.

10.1101/2024.08.25.609566 — plant biology — Posted on 2024-08-25

1162 The three-dimensional anatomy and dorsoventral asymmetry of the mature Marchantia polymorpha meristem develops from a symmetrical gemma meristem

Spencer, V.; Wallner, E.-S.; Jandrasits, K.; Edelbacher, N.; Mosiolek, M.; Dolan, L.

10.1101/2024.08.23.609409 — plant biology — Posted on 2024-08-25

1163 Predicting in vivo concentrations of dietary hop phytoestrogens by physiologically based kinetic modeling

Stevanoska, M.; Beekmann, K.; Punt, A.; Sturla, S.; Aichinger, G.

10.1101/2024.08.23.609337 — pharmacology and toxicology — Posted on 2024-08-25

1164 A Comprehensive Evaluation of Self Attention for Detecting Feature Interactions

Jabeen, S.; Ben-Hur, A.

10.1101/2024.08.23.609428 — bioinformatics — Posted on 2024-08-25

1165 SQANTI-reads: a tool for the quality assessment of long read data in multi-sample lrRNA-seq experiments.

Keil, N.; Monzo, C.; McIntyre, L.; Conesa, A.

10.1101/2024.08.23.609463 — bioinformatics — Posted on 2024-08-25

1166 SMeta, a binning tool using single-cell sequences to aid reconstructing metageome species accurately

Zhang, Y.; Cheng, M.; Ning, K.

10.1101/2024.08.25.609542 — bioinformatics — Posted on 2024-08-25

1167 A systematic evaluation of computational methods for cell segmentation

Wang, Y.; Zhao, J.; Xu, H.; Han, C.; Tao, Z.; Zhou, D.; Geng, T.; Liu, D.; Ji, Z.

10.1101/2024.01.28.577670 — bioinformatics — Posted on 2024-08-25

1168 Fibril Paint: a class of amyloid-targeting peptides

Pedrola, J. A.; Dekker, F. A.; Guttmann, K.; van Leeuwen, L. M.; Singh, S.; Mayer, G.; Garfagnini, T.; Friedler, A.; Rudiger, S. G. D.

10.1101/2024.08.25.609586 — biochemistry — Posted on 2024-08-25

1169 Integrated structural model of the palladin-actin complex using XL-MS, docking, NMR, and SAXS

Sargent, R.; Liu, D. H.; Yadav, R.; Glennenmeier, D.; Bradford, C. W.; Urbina, N.; Beck, M. R.

10.1101/2024.08.25.609580 — biochemistry — Posted on 2024-08-25

1170 Screening macrocyclic peptide libraries by yeast display allows control of selection process and affinity ranking

Linciano, S.; Mazzocato, Y.; Romanyuk, Z.; Vascon, F.; Soler, L. F.; Will, E.; Xing, Y.; Chen, S.; Kumada, Y.; Simeoni, M.; Scarso, A.; Cendron, L.; Heinis, C.; Angelini, A.

10.1101/2024.08.24.609237 — biochemistry — Posted on 2024-08-25

1171 New insights into the structure of cellulose in plant cell walls

Cresswell, R.; Deralia, P. K.; Yoshimi, Y.; Brown, S. P.; Dupree, R.; Dupree, P.

10.1101/2024.08.24.609305 — biochemistry — Posted on 2024-08-25

1172 Global adaptive evolution involved in neuroticism and educational behaviors through the spread of anatomically modern humans

Hayakawa, T.; Fujito, N. T.; Moriya, Y.; Terahara, M.; Teshima, K. M.; Takahata, N.; Satta, Y.

10.1101/2024.08.13.604521 — evolutionary biology — Posted on 2024-08-25

1173 Phylogenomics, Classification, and Lifestyle Evolution in Raft- and Nursery Web- Spiders (Araneae: Dolomedidae and Pisauridae)

Yu, K.-P.; Cheng, R.-C.; Haddad, C. R.; Tanikawa, A.; Pett, B. L.; Piacentini, L. N.; Jaeger, P.; Yip, H. Y.; Suzuki, Y.; Henrard, A.; Painting, C. J.; Vink, C. J.; Hebets, E. A.; Harvey, M. S.; Kuntner, M.

10.1101/2024.08.23.609317 — evolutionary biology — Posted on 2024-08-25

1174 Temperature and Pressure Shaped the Evolution of Antifreeze Proteins in Polar and Deep Sea Zoarcoid Fishes

Bogan, S. N.; Surendran, N.; Hotaling, S.; Desvignes, T.; Bista, I.; Lins, L. S. F.; Eilertsen, M. H.; Le Francois, N. R.; Algayer, T.; Hamilton, S. L.; Frandsen, P. B.; Hoffmann, F. G.; Kelley, J. L.

10.1101/2024.08.24.609455 — evolutionary biology — Posted on 2024-08-25

1175 A Dimeric SINE Discovered in Shrew Mole is Structurally Similar to Primate Alu

Kosushkin, S. A.; Vassetzky, N. S.; Borodulina, O. R.; Kramerov, D. A.

10.1101/2024.08.25.609555 — molecular biology — Posted on 2024-08-25

1176 Effectiveness of Exercise Intervention in Preventing Active Arthritis Exacerbation in an SKG Mouse Model of Rheumatoid Arthritis

Ozone, K.; Kumagai, T.; Arakawa, K.; Sugasawa, T.; Gu, W.; Kawabata, S.; Shimada, N.; Takahashi, H.; Yoneno, M.; Minegishi, Y.; Takahata, K.; Sato, M.; Oka, Y.; Kanemura, N.

10.1101/2024.08.25.609287 — molecular biology — Posted on 2024-08-25

1177 Sodium Chloride Promotes the Growth of Bacterial Soil Isolate and Antimicrobial Activity of Polymixin B

Singh, D. K.

10.1101/2024.08.24.609488 — microbiology — Posted on 2024-08-25

1178 Effects of lambda-cyhalothrin on gut microbiota and related bile acid metabolism in mice

Zheng, W.; Jin, M.; Xu, L.; Wang, J.; Rietjens, I.

10.1101/2024.08.24.609540 — microbiology — Posted on 2024-08-25

1179 Identification of a mesodermal progenitor for the pro-definitive angio-hematopoietic lineage

Lazarov, T.; Loyher, P.-L.; Yang, H.; Choo, Z.-N.; Deng, Z.; Nowotschin, S.; Kuo, Y.-Y.; Zhou, T.; Alberdi-Gonzalez, A.; Stumm, R.; Mass, E.; Gomez Perdiguero, E.; Hadjantonakis, A.-K.; Geissmann, F.

10.1101/2024.08.24.609533 — immunology — Posted on 2024-08-25

1180 A Unified Atlas of T cell Glycophysiology

Izzati, F. N.; Choksi, H.; Giuliana, P.; Abd-Rabbo, D.; Elsaesser, H.; Blundell, A.; Affe, V.; Kannen, V.; Jame-Chenarboo, Z.; Schmidt, E.; Kuypers, M.; Avila, D. B.; Chiu, E. S. Y.; Badmaev, D.; Cui, H.; Matthews, J.; Mallevaey, T.; Macauley, M. S.; Brooks, D. G.; Edgar, L. J.

10.1101/2024.08.24.609521 — immunology — Posted on 2024-08-25

1181 Transitions in dynamical regime and neural mode underlie perceptual decision-making

Luo, T. Z.; Kim, T. D.; Gupta, D.; Bondy, A. G.; Kopec, C. D.; Elliott, V. A.; DePasquale, B.; Brody, C.

10.1101/2023.10.15.562427 — neuroscience — Posted on 2024-08-25

1182 The Temporal Profile of Dual-task Interference in the Human Brain

Hashemirad, S. R.; Vaziri-Pashkam, M.; Abbaszadeh, M.

10.1101/2023.11.06.565914 — neuroscience — Posted on 2024-08-25

1183 TAF1-dependent transcriptional dysregulation underlies multiple sclerosis

Rodriguez-Lopez, C.; Hernandez, I. H.; Terron-Bautista, J.; Agirre, E.; Lozano-Munoz, D.; Pose-Utrilla, J.; Garcia-Ortiz, I.; Lucas-Santamaria, M.; Ruiz-Blas, I.; Gonzalez-Bermejo, M.; Ortega, M. C.; Chara, J. C.; Martinez, Z.; Perez-Cerda, F.; Fransen, N. L.; Martinez-Jimenez, M.; Sancho-Gonzalez, B.; Perez-Samartin, A.; Kabbe, M.; Zheng, C.; Casado-Barbero, M.; Santos-Galindo, M.; Borroto, A.; Alarcon, B.; Clemente, D.; Toma, C.; Matute, C.; Cortes-Ledesma, F.; Castelo-Branco, G.; Lucas, J. J.

10.1101/2024.08.23.609325 — neuroscience — Posted on 2024-08-25

1184 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment

Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.

10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-25

1185 Meta-analysis of gonadal transcriptome provides novel insights into sex change mechanism across protogynous fishes

Nozu, R.; Kadota, M.; Nakamura, M.; Kuraku, S.; Bono, H.

10.1101/2023.07.09.545663 — zoology — Posted on 2024-08-25

1186 Rearrangement of 3D genome organization in breast cancer epithelial - mesenchymal transition and metastasis organotropism

Das, P.; San Martin, R.; Hong, T.; McCord, R. P.

10.1101/2024.08.23.609227 — cancer biology — Posted on 2024-08-25

1187 Super-Enhancer Driven ZFP36L1 Promotes PD-L1 Expression in Infiltrative Gastric Cancer

Wei, X.; Liu, J.; Cheng, J.; Cai, W.; Xie, W.; Wang, K.; Lin, L.; Hou, J.; Cai, J.; Zhuo, H.

10.1101/2024.05.22.595316 — cancer biology — Posted on 2024-08-25

1188 Optimized Dosing and Delivery of Bacteriophage Therapy for Wound Infections

Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zhang, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Pourtois, J.; Chang, T. H. W.; Blankenberg, F. G.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P. L.

10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-08-25

1189 Intrinsically Disordered Regions Define Unique Protein Interaction Networks in CHD Family Remodelers

Tabar, M. S.; Parsania, C.; Giardina, C.; Feng, Y.; Wong, A. C.; metierre, C.; Nagarajah, R.; Dhungel, B. P.; Rasko, J. E.; Bailey, C. G.

10.1101/2024.08.25.609601 — biochemistry — Posted on 2024-08-25

1190 Glucocorticoids desensitize hypothalamic CRH neurons to norepinephrine and somatic stress activation via rapid nitrosylation-dependent regulation of α1 adrenoreceptor trafficking

Weiss, G. L.; Harrison, L. M.; Jiang, Z.; Nielsen, A. M.; Feygin, M. S.; Nguyen, S.; Tirrell, P. S.; Tasker, J. G.

10.1101/2024.07.29.605704 — neuroscience — Posted on 2024-08-25

1191 Scene context and attention independently facilitate MEG decoding of object category

Leticevscaia, O.; Brandman, T.; Peelen, M. V.

10.1101/2024.06.30.601374 — neuroscience — Posted on 2024-08-25

1192 Serpina1e mediates the exercise-induced enhancement of hippocampal memory

Kim, H.; Shin, S.; Kim, J.-S.; Park, H.; Han, J.

10.1101/2024.08.11.607526 — neuroscience — Posted on 2024-08-25

1193 Predicting the alternative conformation of a known protein structure based on the distance map of AlphaFold2

Li, J.; Zhu, Z.; Song, C.

10.1101/2024.06.09.598121 — biophysics — Posted on 2024-08-25

1194 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health

Aranda-Diaz, A.; Vickers, E. N.; Murie, K.; Palmer, B.; Hathaway, N.; Gerlovina, I.; Boene, S.; Garcia-Ulloa, M.; Cistero, P.; Katairo, T.; Semakuba, F. D.; Nsengimaana, B.; Gwarinda, H.; Garcia-Fernandez, C.; Da Silva, C.; Datta, D.; Kiyaga, S.; Wiringilimaana, I.; Fekele, S. M.; Parr, J. B.; Conrad, M.; Raman, J.; Tukwasibwe, S.; Ssewanyana, I.; Rovira-Vallbona, E.; Tato, C. M.; Briggs, J.; Mayor, A.; Greenhouse, B.

10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-25

1195 Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1

Smoom, R.; May, C. L.; Lichtental, D.; Skordalakes, E.; Kaestner, K. H.; Tzfati, Y.

10.1101/2024.02.26.582005 — genetics — Posted on 2024-08-25

1196 A CRISPR-Nonhomologous End-Joining-based strategy for rapid and efficient gene disruption in Mycobacterium abscessus

Zeng, S.; Ju, Y.; Alam, M. S.; Lu, Z.; Hameed, H. M. A.; Li, L.; Tian, X.; Fang, C.; Fang, X.; Ding, J.; Wang, X.; Hu, J.; Wang, S.; Zhang, T.

10.1101/2024.01.29.577284 — microbiology — Posted on 2024-08-25

1197 Simulating the growth of TAF15 inclusions in neuron soma

Kuznetsov, A. V.

10.1101/2024.07.14.603428 — biophysics — Posted on 2024-08-25

1198 Pre-Assembly NGS Correction of ONT Reads Achieves HiFi-Level Assembly Quality

Mozheiko, E.; Yi, H.; Lu, A.; Kong, H.; Hou, Y.; Zhou, Y.; Gao, H.

10.1101/2024.07.12.603260 — genomics — Posted on 2024-08-25

1199 Ground nesting of soft eggs by extinct birds and a new parity mode switch hypothesis for the evolution of animal reproduction

Guimaraes, M. J.; Wang, J.; Zhang, X.; Sun, Q.; Cerqueira, M. F.; Chung, Y.-H.; Deng, R.; Guo, B.; Alpuim, P.; Ma, F.; Wang, X.; Yen, T.-C.

10.1101/2024.08.15.607182 — evolutionary biology — Posted on 2024-08-25

1200 Neosynthesized polarized and non-polarized plasma membrane cargoes follow distinct trafficking routes in Aspergillus nidulans

Sagia, G. M.; Georgiou, X.; Chamilos, G.; Diallinas, G.; Dimou, S.

10.1101/2024.04.24.590866 — cell biology — Posted on 2024-08-25

1201 Signal transduction pathways controlling Ins2 gene activity and β cell state transitions

Chu, J.; Sabbineni, B.; Cen, H. H.; Hu, X.; Sun, W. G.; Brownrigg, G. P.; Xia, Y. H.; Rogalski, J.; Johnson, J. D.

10.1101/2024.06.06.597838 — cell biology — Posted on 2024-08-25

1202 Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion

Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Ohno, T.; Yokoi, N.; Yamada, Y.; Suzuki, A.

10.1101/2024.08.15.608033 — cell biology — Posted on 2024-08-25

1203 Monitoring DNA double strand break repair in Saccharomyces cerevisiae at high throughput and high resolution

Shalev Ezra, Y.; Saguy, A.; Levin, G.; Weiss, L. E.; Alalouf, O.; Shechtman, Y.

10.1101/2024.08.23.609327 — cell biology — Posted on 2024-08-25

1204 Alphavirus infection triggers selective cytoplasmic translocation of nuclear RBPs with moonlighting antiviral roles

Kamel, W.; Ruscica, V.; Embarc-Buh, A.; R. de Laurent, Z.; Garcia-Moreno, M.; Demyanenko, Y.; Madhusudhan, M.; Iselin, L.; Järvelin, A.; Hannan, M.; Kitano, E.; Moore, S.; Merits, A.; Davis, I.; Mohammed, S.; Castello, A.

10.1101/2021.10.06.463336 — microbiology — Posted on 2024-08-25

1205 One N-glycan regulates natural killer cell antibody-dependent cell-mediated cytotoxicity and modulates Fc γ receptor IIIa / CD16a structure

Kremer, P. G.; Lampros, E. A.; Blocker, A. M.; Barb, A. W.

10.1101/2024.06.17.599285 — immunology — Posted on 2024-08-25

1206 Meta-Analysis Reveals That Explore-Exploit Decisions are Dissociable by Activation in the Dorsal Lateral Prefrontal Cortex and the Anterior Cingulate Cortex

Sazhin, D.; Dachs, A.; Smith, D. V.

10.1101/2023.10.21.563317 — neuroscience — Posted on 2024-08-25

1207 Dendritically localized RNAs are packaged as diversely composed ribonucleoprotein particles with heterogeneous copy number states

Tarannum, R.; Mun, G.; Quddos, F.; Swanger, S. A.; Steward, O.; Farris, S.

10.1101/2024.07.13.603387 — neuroscience — Posted on 2024-08-25

1208 Disrupted stimulus encoding shapes tactile perception in autism.

Semelidou, O.; Gauvrit, T.; Vandromme, C.; Cornier, A.; Saint-Jean, A.; Le Feuvre, Y.; Ginger, M.; Frick, A.

10.1101/2024.08.08.607129 — neuroscience — Posted on 2024-08-25

1209 Stable sequential dynamics in prefrontal cortex represents subjective estimation of time

Li, Y.; Yin, W.; Wang, X.; Li, J.; Zhou, S.; Ma, C.-L.; Yuan, P.; Li, B.-M.

10.1101/2024.02.26.582071 — neuroscience — Posted on 2024-08-25

1210 Shared and distinct neural signatures of feature and spatial attention

Yang, A.; Tian, J.; Wang, W.; Liu, J.; Zhou, L.; Zhou, K.

10.1101/2023.08.20.554014 — neuroscience — Posted on 2024-08-25

1211 Telomere length sensitive regulation of Interleukin Receptor 1 type 1 (IL1R1) by the shelterin protein TRF2 modulates immune signalling in the tumour microenvironment

10.1101/2021.12.07.471419 — cancer biology — Posted on 2024-08-25

1212 PiNUI: A Dataset of Protein-Protein Interactions for Machine Learning

Dubourg-Felonneau, G.; Wesego, D. M.; Akiva, E.; Varadan, R.

10.1101/2023.12.12.571298 — bioinformatics — Posted on 2024-08-25

1213 Method for Identifying Proteomic Biomarkers of Health

Zlobina, K.; Gopinath, A.; Thubagere, A.

10.1101/2023.12.06.570488 — bioinformatics — Posted on 2024-08-25

1214 Lightweight taxonomic profiling of long-read metagenomic datasets with Lemur and Magnet

Sapoval, N.; Liu, Y.; Curry, K.; Kille, B.; Huang, W.; Kokroko, N.; Nute, M. G.; Tyshaieva, A.; Dilthey, A. T.; Molloy, E.; Treangen, T. J.

10.1101/2024.06.01.596961 — bioinformatics — Posted on 2024-08-25

1215 Treatment with Metal-Organic Frameworks (MOFs) elicits secondary metabolite accumulation in Aquilaria crassna (Agarwood) callus culture

Overmans, S.; Alflayyeh, Y.; Gutierrez, S.; Aldlaigan, Y. I.; Lauersen, K. J.

10.1101/2024.08.23.609323 — biochemistry — Posted on 2024-08-25

1216 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.

10.1101/2024.02.09.579733 — genetics — Posted on 2024-08-25

1217 Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation

Lai, W.-Y.; Hsu, S.-K.; Futschik, A.; Schloetterer, C.

10.1101/2024.08.06.606803 — evolutionary biology — Posted on 2024-08-25

1218 Increased offspring size and reduced gestation length in an ectothermic vertebrate under a worst-case climate change scenario

Hubert, D. L.; Bentz, E. J.; Mason, R. T.

10.1101/2023.11.25.568677 — ecology — Posted on 2024-08-25

1219 PI(4)P recruits CIDE proteins to promote the formation of unilocular lipid droplets during adipogenesis and hepatic steatosis

Wu, J.; Gao, M.; Wu, X.; Liu, Y.; Du, X.; Liang, Y.; Ma, C.; Li, P.; Chen, F.-J.; Yang, H.

10.1101/2024.08.22.609036 — cell biology — Posted on 2024-08-25

1220 Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4+ T cell response

Chudnovskiy, A.; Castro, T. B.; Nakandakari-Higa, S.; Cui, A.; Lin, C.-H.; Sade-Feldman, M.; Phillips, B. K.; Pae, J.; Mesin, L.; Bortolatto, J.; Schweitzer, L. D.; Pasqual, G.; Lu, L.-F.; Hacohen, N.; Victora, G. D.

10.1101/2022.10.25.513771 — immunology — Posted on 2024-08-25

1221 Patient mutations in DRP1 perturb synaptic maturation of cortical neurons

Baum, T. B.; Bodnya, C.; Costanzo, J.; Gama, V.

10.1101/2024.08.23.609462 — cell biology — Posted on 2024-08-25

1222 Oxtyocin and vasopressin 1a receptor alterations in the superior temporal sulcus and hypothalamus in schizophrenia

Snowden, A. W.; Schwartz, S. E.; Smith, A. L.; Goodman, M. M.; Freeman, S. M.

10.1101/2024.08.23.609421 — neuroscience — Posted on 2024-08-25

1223 Uncovering methylation-dependent genetic effects on regulatory element function in diverse genomes

Petersen, R. M.; Vockley, C. M.; Lea, A. J.

10.1101/2024.08.23.609412 — genomics — Posted on 2024-08-24

1224 Single-cell analysis of the somatic mutational landscape in human chondrocytes during aging and in osteoarthritis

Ren, P.; Zheng, C.; Pang, Y.; Sun, S.; Wang, Q.; Xu, W.; Lee, M.; Qiang, Y.; Lu, Z.; Zhou, M.; He, J.; Liu, N.-N.; Maslov, A. Y.; Dong, X.; Gao, J.; Zhang, C.; Vijg, J.

10.1101/2024.08.24.609506 — genomics — Posted on 2024-08-25

1225 Dynamic convergence of autism disorder risk genes across neurodevelopment

Fernandez Garcia, M.; Retallick-Townsley, K.; Pruitt, A.; Davidson, E.; Dai, Y.; Fitzpatrick, S. E.; Sen, A.; Cohen, S.; Livoti, O.; Khan, S.; Dossou, G.; Cheung, J.; Deans, P. J. M.; Wang, Z.; Huckins, L.; Hoffman, E.; Brennand, K.

10.1101/2024.08.23.609190 — genetics — Posted on 2024-08-24

1226 Transcriptomic analysis and high throughput functional characterization of human induced pluripotent stem cell derived sensory neurons

Truong, V.; Brougher, J.; Strassmaier, T.; Lu, I.; George, D.; Price, T. J.; Randolph, A.; Obergrussberger, A. R.; Haedo, R.; Fertig, N.; Walsh, P.

10.1101/2024.08.23.607310 — cell biology — Posted on 2024-08-24

1227 State modulation in spatial networks with three interneuron subtypes

Edwards, M. M.; Rubin, J.; Huang, C.

10.1101/2024.08.23.609417 — neuroscience — Posted on 2024-08-24

1228 Brain structure and activity predicting cognitive maturation in adolescence

Zhu, J.; Garin, C. M.; Qi, X.-L.; Machado, A.; Wang, Z.; Ben Hamed, S.; Stanford, T. R.; Salinas, E.; Whitlow, C. T.; Anderson, A. W.; Zhou, X. M.; Calabro, F.; Luna, B.; Constantinidis, C.

10.1101/2024.08.23.608315 — neuroscience — Posted on 2024-08-24

1229 Gesture encoding in human left precentral gyrus neuronal ensembles

Vargas-Irwin, C. E.; Hosman, T.; Gusman, J. T.; Pun, T. K.; Simeral, J. D.; Singer-Clark, T.; Kapitonava, A.; Nicolas, C.; Shah, N. P.; Avansino, D.; Kamdar, F.; Williams, Z.; Henderson, J. M.; Hochberg, L. R.

10.1101/2024.08.23.608325 — neuroscience — Posted on 2024-08-24

1230 Structural Development of Speech Networks in Young Children at Risk for Speech Disorder

Curtis, M.; Bayat, M.; Garic, D.; Alfano, A.; Hernandez, M.; Curzon, M.; Bejarano, A.; Tremblay, P.; Graziano, P.; Dick, A. S.

10.1101/2024.08.23.609470 — neuroscience — Posted on 2024-08-24

1231 Musicality enhances selective attention: spatiotemporal insights from precise separation of simultaneous neural responses

Manting, C. L.

10.1101/2024.08.23.609277 — neuroscience — Posted on 2024-08-25

1232 Phylogenomics, Classification, and Lifestyle Evolution in Raft- and Nursery web- Spiders (Araneae: Dolomedidae and Pisauridae)

Yu, K.-P.; Cheng, R.-C.; Haddad, C. R.; Tanikawa, A.; Pett, B. L.; Piacentini, L. N.; Jager, P.; Yip, H. Y.; Suzuki, Y.; Henrard, A.; Painting, C. J.; Vink, C. J.; Hebets, E. A.; Harvey, M. S.; Kuntner, M.

10.1101/2024.08.23.609317 — evolutionary biology — Posted on 2024-08-24

1233 OPA1 mediates cardiac function and metabolism: in silico and in vivo evidence

Fong-McMaster, C.; Pulente, S. M.; Kennedy, L.; Smith, T. K. T.; Myers, S.; Kanaan, M.; Karam, C.; Cope, M.; Lorenzen-Schmidt, I.; Goergen, C. J.; Fullerton, M. D.; Cuperlovic-Culf, M.; Mulvihill, E. E.; Harper, M.-E.

10.1101/2024.08.23.605375 — biochemistry — Posted on 2024-08-24

1234 Decoding protein glycosylation by an integrative mass spectrometry-based de novo sequencing strategy

Gao, J.; Chen, H.; Yin, H.; Chen, X.; Yang, Z.; Wang, Y.; Wu, J.; Tian, Y.; Shao, H.; Wen, L.; Zhou, H.

10.1101/2024.08.23.609376 — biochemistry — Posted on 2024-08-24

1235 Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing

Hazelbaker, D. Z.; Mehta, J. B.; McGinnis, C.; Santesmasses, D.; Bara, A. M.; Liang, X.; Biondi, T.; Fennell, T.; Homer, N.; Estes, B.; Xie, J.; Norouzi, D.; Molugu, K.; Amunugama, R.; Luo, C.; Amin, P.; Shi, X.; Cochrane, J.; Kumar, S.; Wang, J.; Bakalar, M. H.; Finn, J. D.; O'Connell, D. J.

10.1101/2024.08.23.609471 — genomics — Posted on 2024-08-24

1236 The physical chemistry of interphase loop extrusion

Tortora, M. M. C.; Fudenberg, G.

10.1101/2024.08.23.609419 — genomics — Posted on 2024-08-24

1237 In vivo contribution of Cyp24a1 promoter vitamin D response elements

Meyer, M. B.; Lee, S. M.; Towne, J. M.; Cichanski, S. R.; Kaufmann, M.; Jones, G.; Pike, J. W.

10.1101/2024.08.23.609393 — genomics — Posted on 2024-08-24

1238 Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K Plasmodium falciparum Samples

Balmer, A. J.; White, N. F. D.; Ünlü, E. S.; Lee, C.; Pearson, R. D.; Almagro-Garcia, J.; Ariani, C.

10.1101/2024.08.23.609367 — genomics — Posted on 2024-08-24

1239 Robustness and reliability of single-cell regulatory multi-omics with deep mitochondrial mutation profiling

Weng, C.; Weissman, J. S.; Sankaran, V. G.

10.1101/2024.08.23.609473 — genomics — Posted on 2024-08-24

1240 Evolutionary adaptation under climate change: Aedes sp. demonstrates potential to adapt to warming

Couper, L. I.; Dodge, T. O.; Hemker, J. A.; Kim, B. Y.; Exposito-Alonso, M.; Brem, R. B.; Mordecai, E. A.; Bitter, M. C.

10.1101/2024.08.23.609454 — evolutionary biology — Posted on 2024-08-24

1241 Recontextualizing Eukaryogenesis via Computational Analysis of RNA Processing in 16,449 Archaeal Genomes

Kannan, S.

10.1101/2024.08.23.609445 — evolutionary biology — Posted on 2024-08-24

1242 Dna2 nuclease resolves RNA:DNA hybrids at double-strand breaks

Mojumdar, A.; Granger, C.; Cobb, J.

10.1101/2024.08.23.609401 — molecular biology — Posted on 2024-08-24

1243 The Hemopurifier removes extracellular vesicles and microRNAs from renal perfusates following controlled oxygenated rewarming of discarded donor kidneys

de Necochea Campion, R.; Pesqueira, M.; Vallejos, P.; McCullough, C.; Bloesch, A.; LaRosa, S. P.

10.1101/2024.08.23.609252 — molecular biology — Posted on 2024-08-24

1244 Hydrogen Bonding Magnetic Resonance (HBMR)-based Cyclic Electromagnetic DNA Simulation (CEDS) can affect DNA Hybridization and Conformation

Lee, S. K.; Lee, D. G.; Kim, Y. S.

10.1101/2024.08.24.609483 — molecular biology — Posted on 2024-08-24

1245 MiR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells

Joris, V.; Rosado Balmayor, E.; van Griensven, M.

10.1101/2024.08.23.609420 — molecular biology — Posted on 2024-08-24

1246 LDB1 establishes multi-enhancer networks to regulate gene expression

Aboreden, N. G.; Lam, J. C.; Goel, V. Y.; Wang, S.; Wang, X.; Midla, S. C.; Quijano, A.; Keller, C. A.; Giardine, B. M.; Hardison, R. C.; Zhang, H.; Hansen, A. S.; Blobel, G.

10.1101/2024.08.23.609430 — molecular biology — Posted on 2024-08-24

1247 Proteomic profiling of UV damage repair patches uncovers histone chaperones with central functions in chromatin repair

Plessier, A.; Chansard, A.; Petit, E.; Novion Ducassou, J.; Coute, Y.; Polo, S. E.

10.1101/2024.08.23.609352 — molecular biology — Posted on 2024-08-24

1248 Deep mutational scanning of EccD3 reveals the molecular basis of its essentiality in the mycobacterium ESX secretion system

Trinidad, D. D.; Macdonald, C. B.; Rosenberg, O. S.; Fraser, J. S.; Coyote-Maestas, W.

10.1101/2024.08.23.609456 — microbiology — Posted on 2024-08-24

1249 Efflux pumps and membrane permeability contribute to intrinsic antibiotic resistance in Mycobacterium abscessus

McGowen, K.; Funck, T.; Wang, X.; Zinga, S.; Wolf, I. D.; Akusobi, C.; Denkinger, C. M.; Rubin, E. J.; Sullivan, M. R.

10.1101/2024.08.23.609441 — microbiology — Posted on 2024-08-24

1250 Heterologous Surface Display Reveals Conserved Complement Inhibition and Functional Diversification of Borrelia burgdorferi Elp Proteins

Hill, N.; Matulina, L. M.; MacIntyre, C.; Hassani, M. A.; Thomas, S.; Luban, M.; Ward, I.; Abdalla, A.; Leong, J. M.; Garcia, B. L.; Lemieux, J. E.

10.1101/2024.08.23.609448 — microbiology — Posted on 2024-08-24

1251 Methanol chemoreceptor MtpA- and flagellin protein FliC-dependent methylotaxis determines the spaciotemporal colonization of PPFM in the phyllosphere

Katayama, S.; Shiraishi, K.; Kaji, K.; Kawabata, K.; Tamura, N.; Tani, A.; Yurimoto, H.; Sakai, Y.

10.1101/2024.08.24.609498 — microbiology — Posted on 2024-08-24

1252 Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs

Roys, H.; Arykbayeva, A.; Friedman, S. K.; Gifford, G.; Palmer, E. R.; Rogers, A.; Tran, E. N. H.; Fry, L. G.; Weaver, A.; Bowlin, A. K.; Jones, M. D.; Eledge, M.; Boehme, K. W.; Naumiec, G. R.; Weinkopff, T.

10.1101/2024.08.23.605637 — microbiology — Posted on 2024-08-24

1253 Clostridium scindens: an endocrine keystone species in the mammalian gut

Daniel, S. L.; Ridlon, J. M.

10.1101/2024.08.23.609444 — microbiology — Posted on 2024-08-24

1254 Infection characteristics among Serratia marcescens capsule lineages.

Anderson, M. T.; Himpsl, S. D.; Kingsley, L. G.; Smith, S. N.; Bachman, M. A.; Mobley, H. L. T.

10.1101/2024.08.23.609398 — microbiology — Posted on 2024-08-24

1255 Climate drives geographic variation in individual Peromyscus leucopus immunity against zoonotic disease.

Assis, V. R.; McCain, K.; Munds, R. A.; Brehm, A. M.; Orrock, J. L.; Martin, L. B.

10.1101/2024.08.23.609392 — immunology — Posted on 2024-08-24

1256 Host-Guest binding free energies a la carte: an automated OneOPES protocol

Febrer Martinez, P.; Rizzi, V.; Aureli, S.; Gervasio, F. L.

10.1101/2024.08.23.609378 — biochemistry — Posted on 2024-08-24

1257 Tracing the genetic diversity of the bread wheat D genome

Wang, Z.; Wang, W.; He, Y.; Xie, X.; Yang, Z.; Zhang, X.; Niu, J.; Peng, H.; Yao, Y.; Xie, C.; Xin, M.; Hu, Z.; Sun, Q.; Ni, Z.; Guo, W.

10.1101/2024.08.23.609385 — evolutionary biology — Posted on 2024-08-24

1258 Chronic innate immune impairment and ZIKV persistence in the gastrointestinal tract during SIV infection in pigtail macaques

Tisoncik-Go, J.; Lewis, T. B.; Whitmore, L. S.; Voss, K.; Niemeyer, S.; Dai, J.; Kim, P.; Hubbell, K.; Iwayama, N.; Ahrens, C.; Wangari, S.; Murnane, R.; Edlefsen, P. T.; Guerriero, K. A.; Gale, M.; Fuller, D. H.; O'Connor, M.

10.1101/2024.08.23.609309 — immunology — Posted on 2024-08-24

1259 The chloroplast located HKT transporter plays an important role in sporophyte development in Physcomitrium patens

Yanez-Dominguez, C.; Macedo-Osorio, K. S.; Lagunas-Gomez, D.; Torres-Cifuentes, D. M.; Castillo-Gonzalez, J.; Zavala-Padilla, G. T.; Pantoja, O.

10.1101/2024.08.22.609226 — plant biology — Posted on 2024-08-24

1260 Gasdermin D deficiency attenuates development of ascending aortic dissections in a novel mouse model

Javed, M. J.; Howard, R. M.; Li, H.; Carrasco, L.; Dirain, M. L.; Su, G.; Cai, G.; Upchurch, G.; Jiang, Z.

10.1101/2024.08.22.609270 — physiology — Posted on 2024-08-24

1261 HMGB1 restores a dynamic chromatin environment in the presence of linker histone by deforming nucleosomal DNA

Saunders, H. S.; Chio, U. S.; Moore, C. M.; Ramani, V.; Cheng, Y.; Narlikar, G.

10.1101/2024.08.23.609244 — biochemistry — Posted on 2024-08-24

1262 Mammalian PIEZO channels rectify anionic currents

Wijerathne, T. D.; Bhatt, A.; Jiang, W.; Luo, Y.; Lacroix, J. J.

10.1101/2024.08.23.609388 — biophysics — Posted on 2024-08-24

1263 High-resolution structures of the UapA purine transporter reveal unprecedented aspects of the elevator-type transport mechanism.

Broutzakis, G.; Pyrris, Y.; Akrani, I.; Neuhaus, A.; Mikros, E.; Diallinas, G.; Gatsogiannis, C.

10.1101/2024.08.23.609436 — biophysics — Posted on 2024-08-24

1264 PHIStruct: Improving phage-host interaction prediction at low sequence similarity settings using structure-aware protein embeddings

Gonzales, M. E. M.; Ureta, J. C.; Shrestha, A. M. S.

10.1101/2024.08.24.609479 — bioinformatics — Posted on 2024-08-24

1265 Identification of an intrinsically disordered region (IDR) in arginyltransferase 1 (ATE1)

Cartwright, M.; Parakra, R.; Oduwole, A.; Zhang, F.; Deredge, D. J.; Smith, A. T.

10.1101/2024.08.23.609426 — biochemistry — Posted on 2024-08-24

1266 Poly-alanine-tailing is a modifier of neurodegeneration caused by Listerin mutation

Hung, H.-C.; Costas-Insua, C.; Holbrook, S. E.; Stauffer, J. E.; Martin, P. B.; Müller, T. A.; Schroeder, D. G.; Kigoshi-Tansho, Y.; Xu, H.; Rudolf, R.; Cox, G. A.; Joazeiro, C.

10.1101/2024.08.24.608776 — biochemistry — Posted on 2024-08-24

1267 De novo designed inhibitor confers protection against lethal toxic shock

Ragotte, R. J.; Liang, H.; Berman, J. M.; Gloegl, M.; Schramek, D.; Melnyk, R.; Baker, D.

10.1101/2024.08.23.608890 — microbiology — Posted on 2024-08-24

1268 The transcription factor RIP140 regulates interferon γ signaling in breast cancer

Jalaguier, S.; Kuehn, A.; Petitpas, C.; Dulom, A.; Jacquemont, R.; Assi, C.; Sixou, S.; Jeschke, U.; Colinge, J.; Cavailles, V.

10.1101/2024.02.15.580503 — cancer biology — Posted on 2024-08-24

1269 Flexible reproductive seasonality in Africa-dwelling papionins is associated with low environmental productivity and high climatic unpredictability

Dezeure, J.; Dagorrette, J.; Burtschell, L.; Chowdhury, S.; Lukas, D.; Swedell, L.; Huchard, E.

10.1101/2024.05.01.591991 — evolutionary biology — Posted on 2024-08-24

1270 Mathematical modeling suggests heterogeneous replication of Mycobacterium tuberculosis in rabbits

Ganusov, V. V.; Kolloli, A.; Subbian, S. V.

10.1101/2024.02.07.579301 — microbiology — Posted on 2024-08-24

1271 Adhesive and mechanical properties of the glue produced by 25 Drosophila species

Monier, M.; Lorenzi, J.-N.; Narasimha, S.; Borne, F.; Contremoulins, V.; Mevel, L.; Petit, R.; El Hachem, Y.; Graner, F.; Courtier-Orgogozo, V.

10.1101/2024.05.08.593221 — biophysics — Posted on 2024-08-24

1272 Thermodynamic dissipation constrains metabolic versatility of unicellular growth

Cossetto, T.; Rodenfels, J.; Sartori, P.

10.1101/2024.03.21.585772 — biophysics — Posted on 2024-08-24

1273 Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies

Lages, C. F.; Nicoleti, V. Y.; Correa, M. R.; Mausbach, P.; Ramos, F. C.; Araujo, E.; Nascimento, A. Z.; Miqueles, E. X.

10.1101/2024.08.22.609235 — bioinformatics — Posted on 2024-08-24

1274 Prediction of Adeno-Associated Virus Fitness with a Protein Language Based Machine Learning Model

Wu, J.; Qiu, Y.; Lyashenko, E.; Mueller, C.; Choudhury, S. R.

10.1101/2024.08.19.608620 — bioinformatics — Posted on 2024-08-24

1275 Basis of Glucose Selectivity in Sugar Transport Proteins

Andersen, C. G.; Bavnhoj, L.; Brag, S.; Driller, J. H.; Pedersen, B. P.

10.1101/2024.07.19.604285 — biochemistry — Posted on 2024-08-24

1276 A stimulus-computable rational model of habituation in infants and adults

Raz, G.; Cao, A.; Saxe, R.; Frank, M. C.

10.1101/2024.08.21.609039 — animal behavior and cognition — Posted on 2024-08-24

1277 Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells

Clark, C.; Barzegar-Behrooz, A.; Cordani, M.; Shojaei, S.; Ghavami, S.

10.1101/2024.08.09.607348 — molecular biology — Posted on 2024-08-24

1278 Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

Salgueiro, V.; Bertol, J.; Gutierrez, C.; Serrano-Mestre, J. L.; Ferrer-Luzon, N.; Palacios, A.; Pasquina-Lemonche, L.; Espalliat, A.; Lerma, L.; Weinrick, B.; Lavin, J. L.; Elortza, F.; Azkalgorta, M.; Prieto, A.; Buendia-Nacarino, P.; Luque-Garcia, J. L.; Neyrolles, O.; Cava, F.; Hobbs, J.; Sanz, J.; Prados-Rosales, R.

10.1101/2023.11.19.567727 — microbiology — Posted on 2024-08-24

1279 The transition from a non-westernized to westernized gut microbiome in Indian-Immigrants and Indo-Canadians is associated with dietary acculturation

D'Aloisio, L. D.; Ballal, M.; Ghosh, S.; Haskey, N.; Abulizi, N.; Karimianghadim, R.; Liu, C.; Sruthi, P.; Nagarajan, L.; Vasudevan, S.; Shetty, V.; Purandare, M.; Bhaumik, U.; Howlader, D. R.; Pakpour, S.; Barnett, J.; Gibson, D. L.

10.1101/2024.03.04.582285 — microbiology — Posted on 2024-08-24

1280 AVN: A Deep Learning Approach for the Analysis of Birdsong

Koch, T. M. I.; Marks, E.; Roberts, T. F.

10.1101/2024.05.10.593561 — neuroscience — Posted on 2024-08-24

1281 Attention rhythmically shapes sensory tuning

Galas, L.; Donovan, I.; Dugue, L.

10.1101/2023.05.26.542055 — neuroscience — Posted on 2024-08-24

1282 Resilience of A Learned Motor Behavior After Chronic Disruption of Inhibitory Circuits

Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.

10.1101/2023.05.17.541057 — neuroscience — Posted on 2024-08-24

1283 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment

Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.

10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-24

1284 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis

Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.

10.1101/2024.02.28.582624 — biophysics — Posted on 2024-08-24

1285 Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome

Becker, A. P.; Biletch, E.; Kennelly, J. P.; Julio, A. R.; Villanueva, M.; Nagari, R.; Turner, D. W.; Burton, N. R.; Fukuta, T.; Cui, L.; Xiao, X.; Hong, S.-G.; Mack, J. J.; Tontonoz, P.; Backus, K.

10.1101/2024.08.20.608660 — biochemistry — Posted on 2024-08-24

1286 Immigrant birds use payoff biased social learning in spatially variable environments

Chimento, M.; Alarcon-Nieto, G.; Aplin, L. M.

10.1101/2024.06.05.597525 — animal behavior and cognition — Posted on 2024-08-24

1287 Selection can favor a recombination landscape that limits polygenic adaptation

Paree, T.; Noble, L.; Roze, D.; Teotonio, H.

10.1101/2024.08.22.609166 — evolutionary biology — Posted on 2024-08-24

1288 Cell fate specification and conversion generate foveolar cone subtype patterning in human retinal organoids

Hussey, K.; Eldred, K.; Guy, B.; Santiago, C.; Glass, I.; Reh, T. A.; Blackshaw, S.; Goff, L.; Johnston, R. J.

10.1101/2023.01.28.526051 — developmental biology — Posted on 2024-08-24

1289 Flamingo participates in multiple models of cell competition

Bosch, P. S.; Cho, B.; Axelrod, J. D.

10.1101/2023.09.24.559197 — developmental biology — Posted on 2024-08-24

1290 Accessory proteins increase the efficiency of RNA editing by Arabidopsis chloroplast editosomes

Lombana, J.; Hanson, M. R.; Bentolila, S.

10.1101/2024.04.05.588343 — molecular biology — Posted on 2024-08-24

1291 Adiponectin pathway activation dampens inflammation and enhances alveolar macrophage fungal killing via LC3-associated phagocytosis

Goli, S. H.; Lim, J.-Y.; Basaran-Akgul, N.; Templeton, S. P.

10.1101/2024.06.24.600373 — immunology — Posted on 2024-08-24

1292 Effects of early life stress paired with adolescent alcohol consumption on two-bottle choice alcohol drinking behaviors in mice

Perry, T. W.; Carvour, H. M.; Reichert, A. N.; Sneddon, E. A.; Roemer, C. A. E. G.; Gao, Y. Y.; Schuh, K. M.; Shand, N. A.; Quinn, J. J.; Radke, A. K.

10.1101/2023.01.21.524642 — neuroscience — Posted on 2024-08-24

1293 Bronchoalveolar Lavage Single-Cell Transcriptomics Identifies Immune Cells Driving COVID-19 Severity in Patients

Asaba, C. N.; Bitazar, R.; Labonte, P. N.; Bukong, T. N.

10.1101/2024.08.22.609137 — immunology — Posted on 2024-08-23

1294 Selective enrichment of specific bacterial taxa in downy mildew-affected spinach: Comparative analysis in laboratory and field conditions

Goossens, P.; Baremans, K.; Alderkamp, M.; Boshoven, J. C.; Van den Ackerveken, G.; Berendsen, R.

10.1101/2024.08.23.609345 — microbiology — Posted on 2024-08-23

1295 Properties and predictive potential of the pre-ictal oscillatory dynamics in an ex vivo model of epileptiform activity in the different hippocampal subregions

Vagiaki, L.-E.; Xydias, D.; Kefalogianni, M.; Psilodimitrakopoulos, S.; Stratakis, E.; Sidiropoulou, K.

10.1101/2024.08.23.609340 — neuroscience — Posted on 2024-08-23

1296 Assessing male reproductive investment in Papaveraceae using flow cytometry reveals lineage-specific trajectories to pollen-to-ovule ratio reduction

De Vos, J.; Woudstra, Y.; Leitch, I.; Hidalgo, O.

10.1101/2024.08.23.609364 — plant biology — Posted on 2024-08-23

1297 The oncometabolite D-2-hydroxyglutarate promotes DNA hypermethylation at lineage-specific enhancers controlling microglial activation in IDHmut gliomas

Laurenge, A.; Pugliese, P.; Richard, Q.; Mathon, B.; Jouannet, S.; Hayat, Y.; Scuderi, S.; Marijon, P.; Labreche, K.; Alentorn, A.; Verreault, M.; Idbaih, A.; Birzu, C.; Huillard, E.; Pottier, N.; Aurore Desmons, A. D.; Fayache, I.; Kaas, G. A.; Kingsley, P. J.; Marnett, L. J.; Duplus, E.; El-Habr, E.; Salas, L. A.; Mokhtari, K.; Tran, S.; Touat, M.; Bielle, F.; Suva, M. L.; Iavarone, A.; Ceccarelli, M.; Mallat, M.; Sanson, M.; Castro-Vega, L. J.

10.1101/2024.08.23.608811 — cancer biology — Posted on 2024-08-23

1298 The knockdown of the snoRNA-jouvence blocks the cell proliferation and leads to cell death of human primary cancerous glioblastoma cells

JAQUE-CABRERA, L.; BUGGIANI, J.; Bignon, J.; Patricia Daira, P.; Bernoud-Hubac, N.; MARTIN, J.-R.

10.1101/2024.08.23.609357 — cancer biology — Posted on 2024-08-23

1299 Preferential binding of human BRCA1 protein with open X-like conformation of Holliday junction, a homologous recombination intermediate

Kabir, S. H.; K, V.; Pal, N.

10.1101/2024.08.23.609282 — biophysics — Posted on 2024-08-23

1300 A structural perspective on the temperature-dependent activity of enzymes

McLeod, M. J.; Barwell, S. A. E.; Holyoak, T.; Thorne, R. E.

10.1101/2024.08.23.609221 — biophysics — Posted on 2024-08-23

1301 BGC Atlas: A Web Resource for Exploring the Global Chemical Diversity Encoded in Bacterial Genomes

Bagci, C.; Nuhamunada, M.; Goyat, H.; Ladanyi, C.; Sehnal, L.; Blin, K.; Kautsar, S. A.; Tagirdzhanov, A.; Gurevich, A.; Mantri, S.; von Mering, C.; Udwary, D.; Medema, M. H.; Weber, T.; Ziemert, N.

10.1101/2024.08.23.609335 — bioinformatics — Posted on 2024-08-23

1302 Enrichment analysis for spatial and single-cell metabolomics accounting for molecular ambiguity

Wadie, B.; Molenaar, M. R.; Vieira, L. M.; Alexandrov, T.

10.1101/2024.08.23.609355 — bioinformatics — Posted on 2024-08-23

1303 DEK-rRNA interactions regulate ribosome biogenesis and stress response

Xu, N.; Chen, K.; Prell, M.; Liang, P.; Yang, S.; Guo, S.; Lu, Y.; Dorle, S.; Idaghdour, S.; Kappes, F.

10.1101/2024.08.23.609341 — biochemistry — Posted on 2024-08-23

1304 The Transcription Factor Binding Landscape of Mouse Development

Nordin, A.; Zambanini, G.; Jonasson, M. E.; Weiss, T.; van de Grift, Y.; Pagella, P.; Cantu, C.

10.1101/2024.08.23.609315 — genomics — Posted on 2024-08-23

1305 Paradise under threat: the successful invasion of the freshwater shrimp Neocaridina davidi and its parasites on La Reunion Island

Prati, S.; Faivre, L.; de Mazancourt, V.; Sures, B.; Valade, P.

10.1101/2024.08.23.609356 — ecology — Posted on 2024-08-23

1306 Significant and persistent carryover effects in Scots pine

Perry, A.; Beaton, J. K.; Stockan, J. A.; Iason, G. R.; Cottrell, J. E.; Cavers, S.

10.1101/2024.08.23.609343 — ecology — Posted on 2024-08-23

1307 Remarkable similarity in oxygen tolerance among taxonomically diverse marine taxa revealed through hierarchical analysis

Essington, T.; Thorson, J. T.; Deutsch, C. A.

10.1101/2024.08.23.606857 — ecology — Posted on 2024-08-23

1308 Growth patterns of theoretical bite force and jaw musculature in southern sea otters (Enhydra lutris nereis)

Law, C.

10.1101/2024.08.23.609377 — developmental biology — Posted on 2024-08-23

1309 DNA Base Pair Polarities of Pyrimidine(s)-Purine(s) (Pyu) dsDNA induce stronger Hybridization and unique DNA Conformation compared to Purine(s)-Pyrimidine(s) (Puy) dsDNA

Lee, S. K.; Lee, D. G.; Kim, Y. S.

10.1101/2024.08.23.609369 — molecular biology — Posted on 2024-08-23

1310 Cyclic Electromagnetic DNA Simulation (CEDS) can regulate the Functions of Oncogenesis-related miRNAs and DNA Motifs: Protein Signaling Pathways in RAW 264.7 Cells detected by IP-HPLC Analysis

Kim, Y. S.; Lee, S. K.

10.1101/2024.08.23.609321 — molecular biology — Posted on 2024-08-23

1311 The SWI/SNF PBAF complex facilitates REST occupancy at repressive chromatin

Grossi, E.; Nguyen, C. B.; Carcamo, S.; Moran, S.; Kirigin Callau, V.; Filipescu, D.; Hasson, D.; Bernstein, E.

10.1101/2024.08.23.609212 — molecular biology — Posted on 2024-08-23

1312 Spatio-temporal variability of airborne viruses over sub-Antarctic South Georgia: Effects of sampling device and proximity of the ocean

Das, R.; Malard, L.; Pearce, D. A.; Rahlff, J.

10.1101/2024.08.23.609320 — microbiology — Posted on 2024-08-23

1313 Determining the culturability of the bovine rumen bacterial and archaeal microbiota

Buckner, A. M.; Glendinning, L.; Palma Hidalgo, J. M.; van Munster, J. M.; Stevens, M.; Watson, M.; Newbold, C. J.

10.1101/2024.08.23.608987 — microbiology — Posted on 2024-08-23

1314 Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens

Torelli, F.; Matos da Fonseca, D.; Butterworth, S.; Young, J. C.; Treeck, M.

10.1101/2024.08.23.609334 — microbiology — Posted on 2024-08-23

1315 Rhamnose Polysaccharide-Decorated Outer Membrane Vesicles as a Vaccine Candidate Targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Ajay Castro, S.; Thomson, S.; Shaw, H. A.; Zorzoli, A.; Meyer, B. H.; Reglinski, M.; Dorfmueller, H. C.

10.1101/2024.08.23.609347 — microbiology — Posted on 2024-08-23

1316 The immunobiology of persistent intestinal infection by Campylobacter jejuni in the chicken

Gilroy, R. L.; Wedley, A.; Jopson, S.; Hall, J.; Wigley, P.

10.1101/2024.08.23.609314 — immunology — Posted on 2024-08-23

1317 Complement activation at injury sites drives the phagocytosis of necrotic cell debris and resolution of liver injury

Vandendriessche, S.; Mattos, M. S.; Bialek, E. L.; Schuermans, S.; Proost, P.; Marques, P. E.

10.1101/2024.08.23.609344 — immunology — Posted on 2024-08-23

1318 Expanding the biotechnological scope of metabolic sensors through computation-aided designs

Orsi, E.; Schulz-Mirbach, H.; Cotton, C. A. R.; Satanowski, A.; Petri, H.; Arnold, S. L.; Grabarczyk, N.; Verbakel, R.; Jensen, K. S.; Donati, S.; Paczia, N.; Glatter, T.; Kueffner, A. M.; Chotel, T.; Schillmueller, F.; De Maria, A.; He, H.; Lindner, S. N.; Noor, E.; Bar-Even, A.; Erb, T. J.; Nikel, P. I.

10.1101/2024.08.23.609350 — synthetic biology — Posted on 2024-08-23

1319 Air Pocket for a Non-Air-Breathing Fish: Developing Respirometry Methodology for the critically endangered Delta Smelt

Kwan, G. T.; Mauduit, F.; Zillig, K. W.; Yanagitsuru, Y. R.; Baird, S. E.; Cocherell, D. E.; Fangue, N. A.

10.1101/2024.08.23.609307 — physiology — Posted on 2024-08-23

1320 Individual Differences in the Correspondence Between Psychological and Physiological Stress Indicators

Hilger, K.; Talic, I.; Renner, K.-H.

10.1101/2024.08.23.609328 — physiology — Posted on 2024-08-23

1321 Modeling statin-induced myopathy with human iPSCs reveals that impaired proteostasis underlies the myotoxicity and is targetable for the prevention

Zhao, X.; Ni, L.; Kubo, M.; Matsuto, M.; Sakurai, H.; Shimizu, M.; Takahashi, Y.; Sato, R.; Yamauchi, Y.

10.1101/2024.08.23.608904 — pharmacology and toxicology — Posted on 2024-08-23

1322 Estimating ancestral states of complex characters: a case study on the evolution of feathers

Cockx, P.; Benton, M. J.; Keating, J. N.

10.1101/2024.08.23.609354 — paleontology — Posted on 2024-08-23

1323 A coregulatory influence map of glioblastoma heterogeneity and plasticity - From cells in vitro to tumors and back again

Bernhard, C.; Geles, K.; Pawlak, G.; Dhifli, W.; Dispot, A.; Dusol, J.; Kondratova, M.; Martin, S.; Messe, M.; Reita, D.; Tulasne, D.; Van Seuningen, I.; Entz-Werle, N.; Ciafre, S.-A.; Dontenwill, M.; Elati, M.

10.1101/2024.08.23.609303 — cancer biology — Posted on 2024-08-23

1324 SpatialLeiden - Spatially-aware Leiden clustering

Müller-Bötticher, N.; Sahay, S.; Eils, R.; Ishaque, N.

10.1101/2024.08.23.609349 — bioinformatics — Posted on 2024-08-23

1325 Accurate antibody loop structure prediction enables zero-shot design of target-specific antibodies

Bang, Y.; Choi, Y.-A.; Gu, J.; Kwon, S.; Lee, D.; Lee, M. S.; Lee, S. J.; Lim, J.; Maeng, J. Y.; Nam, J.; Noh, J.; Oh, H.; Park, S.-Y.; Park, T.; Seo, S.; Seok, C.; Song, M. Y.; Won, J.; Woo, H.; Yang, J.; Yoon, M. J.; Bae, W.; Kim, J.; Lee, D.; Lee, J.; Lee, Y.; Yu, H.

10.1101/2024.08.23.609114 — bioengineering — Posted on 2024-08-23

1326 Structural basis for the strict substrate specificity of beta-D-galactofuranosidase from Streptomyces sp. JHA19

Fujio, N.; Yamada, C.; Kashima, T.; Matsunaga, E.; Nash, R. J.; Takegawa, K.; Fushinobu, S.

10.1101/2024.08.23.609336 — biochemistry — Posted on 2024-08-23

1327 Identification and structural characterization of a novel acetyl xylan esterase from Aspergillus oryzae

Yamada, C.; Kato, T.; Shiono, Y.; Koseki, T.; Fushinobu, S.

10.1101/2024.08.23.609331 — biochemistry — Posted on 2024-08-23

1328 ARTIC RSV amplicon sequencing reveals global RSV genotype dynamics.

Maloney, D. M.; Fernandes, G.; Jasim, S.; Williams, T.; Namugenyi, S.; Carr, M.; Meyer, J. R.; Sharma, A.; Marshal, L.; Nunley, B. E.; Xie, H.; Carvajal, M.; Kunerth, H. D.; O'Toole, A.; Weixler, A.; Lanter, K. R.; Gonzalez, G.; Sereewit, J.; Guevara, R.; Astbury, S.; Fanning, P. M.; Benitez, D.; Fernandez, J. C.; Cardenas, P.; Hare, D.; Greninger, A.; Williams, T.; Nebbia, G.; Fries, A. C.; McClure, P.; Roychoudhury, P.; Wang, X.; Saha, S.; Dewar, R.; Templeton, K. E.; Rambaut, A.

10.1101/2024.08.23.609324 — genomics — Posted on 2024-08-23

1329 Inferring plant community phenology via bee-collected pollen

Wizenberg, S. B.; Pepinelli, M.; Do, B. N.; Moubony, M.; Tamashekan, D.; Conflitti, I. M.; Zayed, A.

10.1101/2024.08.23.609319 — ecology — Posted on 2024-08-23

1330 Gaps in the global protection of terrestrial genetic diversity

Schultz, J. T.; Geldmann, J.; Theodoridis, S.; Nogues-Bravo, D.

10.1101/2024.08.23.609342 — ecology — Posted on 2024-08-23

1331 Moult cycle and setal development of the Atlantic ditch shrimp Palaemon varians Leach, 1814

Kim, K.; Antcliffe, J.; Daley, A. C.; Robinson-Rechavi, M.

10.1101/2024.08.23.609361 — developmental biology — Posted on 2024-08-23

1332 FGF9 treatment reduces off-target chondrocytes from iPSC-derived kidney organoids

Joris, V.; Schumacher, A.; Marks, P.; Eischen-Loges, M.; van Griensven, M.; LaPointe, V.

10.1101/2024.08.23.609318 — cell biology — Posted on 2024-08-23

1333 Monitoring DNA double strand break repair in Saccharomyces cerevisiae at high throughput and high resolution

Shalev Ezra, Y.; Saguy, A.; Levin, G.; Weiss, L.; Alalouf, O.; Shechtman, Y.

10.1101/2024.08.23.609327 — cell biology — Posted on 2024-08-23

1334 Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in MPS VII

Mandal, N.; Das, A.; Datta, R.

10.1101/2024.08.23.609363 — cell biology — Posted on 2024-08-23

1335 Odoribacter splanchnicus mitigates Salmonella-induced gut inflammation and its associated pathogenesis via its secreted bacteriocin

Hajra, D.; Mukherjee, D.; Vij, R.; Rajmani, R. S.; Dadireddy, V.; Das, D.; Hussain, T.; Ganji, M.; Tatu, U.; Chakravortty, D.

10.1101/2024.08.23.609322 — microbiology — Posted on 2024-08-23

1336 Heat shock protein 90 is a master regulator of HIV-1 latency

Noorsaeed, S.; Al Burtamani, N.; Rokan, A.; Fassati, A.

10.1101/2024.08.23.609311 — microbiology — Posted on 2024-08-23

1337 Tactile Mechanisms and Afferents Underlying the Rat Pup Transport Response

Ni, Z.; Neifert, C.; Rosete, A.; Albeely, A. M.; Yang, Y.; Pratelli, M.; Brecht, M.; Clemens, A. M.

10.1101/2024.08.23.609194 — neuroscience — Posted on 2024-08-23

1338 Regulation of plant metabolism under elevated CO2

Shokouhi, D.; Hernandez, J. S.; Walther, D.; Kepp, G.; Schwenkert, S.; Leister, D.; Gremmels, J.; Zuther, E.; Alpers, J.; Naegele, T.; Heyer, A. G.

10.1101/2024.08.23.609313 — plant biology — Posted on 2024-08-23

1339 RNA quality control by CCR4 safeguards chromatin integrity and centromere function in Arabidopsis

SHIMADA, A.; Saze, H.

10.1101/2024.08.23.608929 — plant biology — Posted on 2024-08-23

1340 In vivo Antibody Painting for Next Generation Weight Loss Drugs

Kitahara, K.; Rondon, A.; Miller, E.; Mak, H. H.; Loas, A.; Pentelute, B. L.

10.1101/2024.08.22.609257 — bioengineering — Posted on 2024-08-23

1341 A Novel Combinatorial Approach Integrating Experimental and Computational Analysis of Antioxidant Activity: Evaluating Catechin and L-Ascorbic Acid in Serum

Chandra, R.; Rasool, A.; Chidi, C.; Rigaut, S.; Carty, S.; Soubra-Ghaoui, C.

10.1101/2024.08.22.609135 — biochemistry — Posted on 2024-08-23

1342 Treatment with Metal-Organic Frameworks (MOFs) elicits secondary metabolite accumulation in Aquilaria crassna (Agarwood) callus culture

Overmans, S.; Alfayyeh, Y.; Gutierrez, S.; Aldlaigan, Y. I.; Lauersen, K. J.

10.1101/2024.08.23.609323 — biochemistry — Posted on 2024-08-23

1343 The applicability of Regional Red List assessments for soil invertebrates: First assessment of five native earthworm species in Canada

Phillips, H. R. P.; Brown, G. G.; James, S. W.; Mathieu, J.; Reynolds, J. W.; Dharmasiri, M. E.; Singer, C. L.; Briones, M. J. I.; Procter, H. C.; Cameron, E. K.

10.1101/2024.08.23.608777 — ecology — Posted on 2024-08-23

1344 Selection of streptococcal glucan-binding protein C specific DNA aptamers to inhibit biofilm formation

Harkai, A.; Beck, Y. K.; Tory, A.; Meszaros, T.

10.1101/2024.08.23.608024 — molecular biology — Posted on 2024-08-23

1345 Boundaries in the eyes: measure event segmentation during naturalistic video watching using eye tracking

Li, J.; Cheng, Z.; Hao, X.; Liu, W.

10.1101/2024.08.22.609279 — neuroscience — Posted on 2024-08-23

1346 Detecting behavioural oscillations with increased sensitivity: A modification of Brookshire's (2022) AR-surrogate method

Harris, A. M.; Beale, H. A.

10.1101/2024.08.22.609278 — neuroscience — Posted on 2024-08-23

1347 Human melanoma cell lines that possess wild-type BRAF alleles but are dependent on ERBB4 and ERBB2

Dwivedi, V.; Lucas, L. M.; Cooke, R.; Davis, J.; Wilson, E.; Scott, M.; O'Daniel, K.; Dion, C.; Kerley, J.; Zelan, M.; DeFeo, N.; Huffman, V.; Ingrao, M. N.; Riese, D. J.

10.1101/2024.08.22.609260 — cancer biology — Posted on 2024-08-23

1348 The probability of cryptic pocket opening controls functional tradeoffs in filovirus immune evasion.

Mallimadugula, U. L.; Cruz, M. A.; Vithani, N.; Zimmerman, M. I.; Bowman, G. R.

10.1101/2024.08.22.609218 — biophysics — Posted on 2024-08-23

1349 Protein sequence classification using natural language processing techniques

Perveen, H.; Weeds, J.

10.1101/2024.08.23.609306 — bioinformatics — Posted on 2024-08-23

1350 Photo-induced changes in tissue stiffness alter epithelial budding morphogenesis in the embryonic lung

Peak, K. E.; Rajaguru, P.; Khan, A.; Gleghorn, J. P.; Obaid, G.; Ferruzzi, J.; Varner, V. D.

10.1101/2024.08.22.609268 — bioengineering — Posted on 2024-08-23

1351 Comparing the impact of sample multiplexing approaches for single-cell RNA-sequencing on downstream analysis using cerebellar organoids

Sarieva, K.; Kagermeier, T.; Lysenkov, V.; Yentuer, Z.; Becker, K.; Matilainen, J.; Casadei, N.; Mayer, S.

10.1101/2024.08.23.609290 — genomics — Posted on 2024-08-23

1352 Residence time structures microbial communities through niche partitioning

Mueller, E. A.; Lennon, J. T.

10.1101/2024.08.22.609267 — ecology — Posted on 2024-08-23

1353 Competition enables rapid adaptation to a warming range edge

Usui, T.; Angert, A.

10.1101/2024.08.22.609250 — ecology — Posted on 2024-08-23

1354 Morphological criteria for staging near-hatching embryos of the domesticated Mallard (Anas platyrhynchos) and Swan Goose (Anser cygnoides)

Arnaout, B.; Brzezinski, K.; Steventon, B.; Field, D. J.

10.1101/2024.08.23.609168 — developmental biology — Posted on 2024-08-23

1355 Regulation of angiogenesis by signal sequence-derived peptides

Ghim, M.; Wei, L.; Jung, J.-J.; The, E.; Kukreja, G.; Neishabouri, A.; Ahmad, A.; Raza, M. Z.; Golbazi, A.; Hedayatyanfard, K.; Nie, L.; Zhang, J.; Sadeghi, M. M.

10.1101/2024.08.22.609269 — cell biology — Posted on 2024-08-23

1356 The dynamics of Staphylococcal infection and their treatment with antibiotics and bacteriophage in the Galleria mellonella model system

Berryhill, B. A.; Gil-Gil, T.; Witzany, C.; Goldberg, D. A.; Vega, N. M. A.; Regoes, R. R.; Levin, B. R.

10.1101/2024.08.23.609294 — microbiology — Posted on 2024-08-23

1357 Terminal tracheal cells of Drosophila are immune privileged to maintain their Foxo-dependent structural plasticity

Bossen, J. M.; Raveendran, R.; He, J.; Roeder, T.

10.1101/2024.08.22.609264 — immunology — Posted on 2024-08-23

1358 Unveiling microglial heterogeneity from single-cell transcriptomics in neurodegenerative diseases

Palma, A.

10.1101/2024.08.23.609299 — neuroscience — Posted on 2024-08-23

1359 Bidirectional locomotion induces unilateral limb adaptations

Hardesty, R. L.; Motjabavi, H.; Gemoets, D. E.; Wolpaw, J. R. L.

10.1101/2024.08.22.609228 — neuroscience — Posted on 2024-08-23

1360 Rapid Changes in Risk Preferences Originate from Bayesian Inference on Parietal Magnitude Representations

de Hollander, G.; Grueschow, M.; Hennel, F.; Ruff, C. C.

10.1101/2024.08.23.609296 — neuroscience — Posted on 2024-08-23

1361 Remodelling of the glycome of B-cell precursor acute lymphoblastic leukemia cells developing drug-tolerance

Oliveira, T.; Zhang, M.; Chen, C.-W.; Packer, N.; von Itzstein, M.; Heisterkamp, N.; Kolarich, D.

10.1101/2024.08.22.609211 — cancer biology — Posted on 2024-08-23

1362 Enzymatic reactions dictated by the 2D membrane environment

Lin, C.-W.; Bai, R.-H.

10.1101/2024.08.22.609272 — biophysics — Posted on 2024-08-23

1363 Flexibility and Hydration of the Qo Site Determine Multiple Pathways for Proton Transfer in Cytochrome bc1

Camilo, S. R. G.; Arantes, G. M.

10.1101/2024.08.22.609217 — biophysics — Posted on 2024-08-23

1364 A multi-omics approach to identify deleterious mutations in plants

Baruch, O.; Levy, A. A.; Mafessoni, F.

10.1101/2024.08.22.609273 — bioinformatics — Posted on 2024-08-23

1365 Automatic crystal identification for crystallography: a comparison between direct methods and artificial intelligence strategies

Lages, C. F.; Nicoleti, V. Y.; Correa, M. R.; Mausbach, P.; Ramos, F. C.; Araujo, E.; Nascimento, A. Z.; Miqueles, E. X.

10.1101/2024.08.22.609235 — bioinformatics — Posted on 2024-08-23

1366 A modular encapsulation system for precision delivery of proteins, nucleic acids and therapeutics

Luong, T. D.; Martel, N.; Rae, J.; Lo, H. P.; Lim, Y.-W.; Wu, Y.; McMahon, K.-A.; Fletcher, N.; Thurecht, K. J.; Johnston, A. P. R.; Ariotti, N.; Hall, T. E.; Parton, R. G.

10.1101/2024.08.22.607124 — bioengineering — Posted on 2024-08-23

1367 A screening setup to streamline in vitro Engineered Living Material cultures with the host

Desai, K.; Sankaran, S.; del Campo, A.; Trujillo, S.

10.1101/2024.08.22.609167 — bioengineering — Posted on 2024-08-23

1368 Pancreatic endocrine cells are transduced by adeno-associated virus serotypes 2 and 9 but not 6

Ahuja, V.; Jeyabalan, S.; Tzanakakis, E. S.

10.1101/2024.08.22.609291 — bioengineering — Posted on 2024-08-23

1369 The Common Marmoset as a Translational Model for Longitudinal Studies of Cognitive Aging and Individual Vulnerability to Decline

Vanderlip, C. R.; Asch, P. A.; Glavis-Bloom, C.

10.1101/2024.08.22.609213 — animal behavior and cognition — Posted on 2024-08-23

1370 Robust identification of orthologous synteny with the Orthology Index and its applications in reconstructing the evolutionary history of plant genomes

Zhang, R.-G.; Shang, H.-Y.; Zhou, M.-J.; Shu, H.; Jia, K.-H.; Ma, Y.-P.

10.1101/2024.08.22.609065 — genomics — Posted on 2024-08-23

1371 Large-scale manipulation of radial positioning does not affect most aspects of genome organization

Guetta, M.; Kariti, H.; Sherman, L.; Israitel, L.; Tel-Paz, M.; Avidan, N.; Shemer, R.; Kaplan, N.

10.1101/2024.08.22.609170 — genomics — Posted on 2024-08-23

1372 Contribution of brain intrinsic branched-chain amino acid metabolismin a novel mouse model of maple syrup urine disease

Kuhs, A. C.; Ohl, L.; Thurston, T.; Singh, J.; Bhuyan, S.; Grandinette, S.; Xu, J.; Siemsgluess, S. A.; Jakher, Y.; Ahrens-Nicklas, R. C.

10.1101/2024.08.22.609255 — genetics — Posted on 2024-08-23

1373 Selection can favor a recombination landscape that limits polygenic adaptation

Paree, T.; Noble, L.; Roze, D.; Teotonio, H.

10.1101/2024.08.22.609166 — evolutionary biology — Posted on 2024-08-23

1374 Climate, population size, and dispersal influences mutational load across the landscape in Vitis arizonica

Fiscus, C. J.; Aguirre-Liguori, J. A.; Gaut, G. R. J.; Gaut, B. S.

10.1101/2024.08.22.609253 — evolutionary biology — Posted on 2024-08-23

1375 Blue light toxicity drives the gut microbiota-mediated lipid accumulation in Drosophila

Takada, Y.; Ichinose, T.; Fuse, N.; Saito, K.; Ikeda-Ohtsubo, W.; Tanimoto, H.; Hori, M.

10.1101/2024.08.22.608892 — evolutionary biology — Posted on 2024-08-23

1376 Damsels in a hidden colour: development of ultraviolet sensitivity and colour patterns in damselfishes (Pomacentridae)

Tettamanti, V.; Marshall, J.; Cheney, K.; Cortesi, F.

10.1101/2024.08.22.609266 — ecology — Posted on 2024-08-23

1377 Leveraging Chlorination-Based Mechanism for Resolving Subcellular Hypochlorous Acid

Tang, F. K.; Tucker, L.; Nadiveedhi, M. R.; Hladun, C.; Morse, J.; Ali, M.; Payne, N.; Schmidt, M.; Leung, K.

10.1101/2024.08.22.609247 — cell biology — Posted on 2024-08-23

1378 Nociceptor Neurons Control Pollution-Mediated Neutrophilic Asthma

Wang, J.-C.; Crosson, T.; Reza Nikpoor, A.; Gupta, S.; Rafei, M.; Talbot, S.

10.1101/2024.08.22.609202 — immunology — Posted on 2024-08-23

1379 Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils

Gautam, R.; Lal, M.; Carroll, M. C.; Mrozek, Z.; Trachsel, T.; Beers, J.; Ruffner, M. A.

10.1101/2024.08.22.609219 — immunology — Posted on 2024-08-23

1380 Vaccination against helminth IL-33-modulators permits immune-mediated parasite ejection

Smyth, D. J.; Hodge, S.; Ong, N.; Richards, J.; Colomb, F.; Shek, V.; Frangova, T.; McSorley, H. J.

10.1101/2024.08.22.609138 — immunology — Posted on 2024-08-23

1381 CD4+ T cells recruit, then engage macrophages in cognate interactions to clear Mycobacterium tuberculosis from the lungs.

Becker, S. H.; Ronayne, C. E.; Bold, T. D.; Jenkins, M. K.

10.1101/2024.08.22.609198 — immunology — Posted on 2024-08-23

1382 SERS Analysis Of Sialic Acid In Single Dendritic Cells Within The Tumor Microenvironment

Xingrui, L.; Lingling, M.; Xiaofei, Y.; Nian, W.; Shiyu, B.; Qiongzhen, Z.; Yu, Y.; Weidong, H.; Zhengding, S.; Jinyao, L.

10.1101/2024.08.22.608950 — immunology — Posted on 2024-08-23

1383 Breastmilk IgG engages the neonatal immune system to instruct host-microbiota mutualism

Shenoy, M. K.; Rico, D.; Gordon, S.; Milburn, L.; Schwensen, J.; Caban, M.; Koch, M. A.

10.1101/2024.08.23.609293 — immunology — Posted on 2024-08-23

1384 On the same wavelength: The relationship between neural synchrony and cognitive ability during movie watching in late childhood and early adolescence

Lyons, K. M.; Ho, W.; Stevenson, R. A.; Owen, A. M.; Stojanoski, B.

10.1101/2024.08.22.609236 — neuroscience — Posted on 2024-08-23

1385 Anxiety and risk-taking behavior maps onto opioid and alcohol polysubstance consumption patterns in male and female mice

Patarino, M.; Wang, Z. C.; Wong, K.; Lee, S. J.; Skillen, E.; Nag, R.; Baskin, B.; Schindler, A. G.

10.1101/2024.08.22.609245 — neuroscience — Posted on 2024-08-23

1386 The Impact of Ketamine and Thiopental Anesthesia onUltraweak Photon Emission and Oxidative-Nitrosative Stress in Rat Brains

Ghaffari, M. K.; Sefati, N.; Esmaeilpour, T.; Salari, V.; Oblak, D.; Simon, C.

10.1101/2024.08.22.609284 — neuroscience — Posted on 2024-08-23

1387 Nageotte nodules in human DRG reveal neurodegeneration in painful diabetic neuropathy

Shiers, S.; Mazhar, K.; Wangzhou, A.; Haberberger, R. V.; Lesnak, J. B.; Sankaranarayanan, I.; Tavares-Ferreira, D.; Cervantes, A.; Funk, G.; Horton, P.; Vines, E.; Dussor, G.; Price, T. J.

10.1101/2024.08.22.609215 — neuroscience — Posted on 2024-08-23

1388 Neuropeptides from a praying mantis: What the loss of pyrokinins and tryptopyrokinins suggests about the endocrine functions of these peptides

Veenstra, J. A.

10.1101/2024.08.22.609177 — zoology — Posted on 2024-08-23

1389 Two residues reprogram immunity receptor kinases to signal in nitrogen-fixing symbiosis

Tsitsikli, M.; Simonsen, B. W.; Larsen, M. M.; Andersen, C. G.; Gysel, K.; Lironi, D.; Kronauer, C.; Rubsam, H.; Luu, T.-B.; Hansen, S. B.; Kaya, G.; Stougaard, J.; Andersen, K. R.; Radutoiu, S.

10.1101/2024.08.22.609144 — plant biology — Posted on 2024-08-23

1390 VRS5 (HvTB1) binds to the promoter of tillering and floral homeotic genes to regulate their expression

Winkelmolen, T.; Colleoni, P.; Moscou, M. J.; hoseinzadeh, p.; Oldach, K.; Schmidt, R.-C.; Immink, R. G. H.; van Esse, G. W.

10.1101/2024.08.22.609225 — plant biology — Posted on 2024-08-23

1391 Deconvolution of cancer methylation patterns determines that altered methylation in cancer is dominated by a non-disease associated proliferation signal

Lalchungnunga, H.; Atasoy, H.; Schwalbe, E. C.; Bacon, C. M.; Strathdee, G.

10.1101/2024.08.22.609153 — cancer biology — Posted on 2024-08-23

1392 Development of an optimized machine learning approach to enhance brain metastatic burden assessment in preclinical models.

Rappaport, J.; Chen, Q.; McGuire, T.; Daugherty-Lopes, A.; Goldszmid, R. S.

10.1101/2024.08.21.608131 — cancer biology — Posted on 2024-08-23

1393 CDK4/6 inhibitors promote senescence-associated lysosomal alterations and enhance sensitivity to lysosomotropic agents in breast cancer

Nehme, J.; Massen, S.; Bravaccini, S.; Zanoni, M.; Gianni, C.; De Giorgi, U.; Soto-Gamez, A.; Altulea, A.; Gheorghe, T.; Wang, B.; Demaria, M.

10.1101/2024.08.22.609150 — cancer biology — Posted on 2024-08-23

1394 Multiplexed Glycan Immunofluorescence Identification of Pancreatic Cancer Cell Subpopulations in Both Tumor and Blood Samples

Binkowski, B.; Klamer, Z.; Gao, C.; Staal, B.; Repesh, A.; Tran, H.-L.; Brass, D. M.; Bartlett, P.; Gallinger, S.; Blomqvist, M.; Morrow, J. B.; Allen, P.; Shi, C.; Singhi, A.; Brand, R.; Huang, Y.; Hostetter, G.; Haab, B. B.

10.1101/2024.08.22.609143 — cancer biology — Posted on 2024-08-23

1395 Virtual Clinical Trials of BMP4 Differentiation Therapy: Digital Twins to Aid Glioblastoma Trial Design

Harbour, N.; Curtin, L.; Hubbard, M. E.; Jackson, P. R.; Rani, V.; Carrano, A.; Farias, V. d. A.; Kenchappa, R.; Quinones-Hinojosa, A.; Owen, M.; Swanson, K. R.

10.1101/2024.08.22.609156 — cancer biology — Posted on 2024-08-23

1396 Microenvironment T-Type calcium channels regulate neuronal and glial processes to promote glioblastoma growth

Dube, C. J.; Zhang, Y.; Saha, S.; Lai, M.; Gibert, M. K.; Escalante, M.; Hudson, K.; Wong, D.; Marcinkiewicz, P.; Yener, U.; Sun, Y.; Xu, E.; Sorot, A.; Mulcahy, E.; Kefas, B. A.; Hanif, F.; Guessous, F.; Patel, M. K.; Schiff, D.; Zong, H.; Purow, B. W.; Holland, E.; Sonkusare, S. K.; Sontheimer, H.; Abounader, R.

10.1101/2024.08.22.609229 — cancer biology — Posted on 2024-08-23

1397 Tetramethylrhodamine self-quenching is a probe of conformational change on the scale of 15 - 25 Angstrom

Girvan, P.; Ying, L.; Dodson, C. A.

10.1101/2024.08.22.609131 — biophysics — Posted on 2024-08-23

1398 Solving the "Blind men and the elephant problem": Additive deep learning of complex high dimensional models from partial faceted datasets

Wu, Y.; Wu, P.-H.; Chambliss, A.; Wirtz, D.; Sun, S.

10.1101/2024.08.22.609223 — bioinformatics — Posted on 2024-08-23

1399 Evolutionary mismatch between nuclear and mitochondrial genomes does not promote reversion mutations in mtDNA.

Franco, M.; Popadin, K.; Woods, D. C.; Khrapko, K.

10.1101/2024.08.21.609033 — bioinformatics — Posted on 2024-08-23

1400 PBAE-PEG based lipid nanoparticles for lung cell-specific gene delivery

Liu, B.; Sajiki, Y.; Sridharan, A.; Stuart, W.; Cui, X.; Siefert, M.; Araki, K.; Ziady, A.; Shi, D.; Whitsett, J. A.; Maeda, Y.

10.1101/2024.08.22.608643 — bioengineering — Posted on 2024-08-23

1401 Dysfunctional mechanotransduction regulates the progression of PIK3CA-driven vascular malformations

Aw, W. Y.; Sawhney, A.; Rathod, M.; Whitworth, C. P.; Doherty, E. L.; Madden, E.; Lu, J.; Westphal, K.; Stack, R. N.; Polacheck, W. J.

10.1101/2024.08.22.609165 — bioengineering — Posted on 2024-08-23

1402 A convenient single-cell newly synthesized transcriptome assay reveals gene expression dynamics during early-stage T-cell activation

Lyu, J.; Xu, X.; Chen, C.

10.1101/2024.08.22.609222 — genomics — Posted on 2024-08-23

1403 Pathogenic fungus expresses effector proteins in combination with a symbiotic virus to behaviourally manipulate housefly hosts

Edwards, S.; Nielsen, K. N.; Will, I.; de Bekker, C.; Kotta-Loizou, I.; De Fine Licht, H. H.

10.1101/2024.08.20.608796 — evolutionary biology — Posted on 2024-08-23

1404 3D scanning measurement method for seed size research

Malik-Roffa, H.; Malik, T.; Tozser, D.; Tothmeresz, B.

10.1101/2024.08.22.609234 — ecology — Posted on 2024-08-23

1405 Open-hardware solutions for light sheet microscopy specimen chambers

Golden, A.; Colombelli, J.; Stelzer, E. H. K.; Pampaloni, F.

10.1101/2024.08.22.609188 — developmental biology — Posted on 2024-08-23

1406 Restoring mechanophenotype reverts malignant properties of ECM-enriched vocal fold cancer

Kaivola, J.; Punovuori, K.; Chastney, M. R.; Miroshnikova, Y. A.; Bertillot, F.; Abdo, H.; Krautgasser, F.; Di Franco, J.; Conway, J. R. W.; Follain, G.; Hagstrom, J.; Makitie, A.; Irjala, H.; Ventela, S.; Hamidi, H.; Scita, G.; Cerbino, R.; Wickstrom, S. A.; Ivaska, J.

10.1101/2024.08.22.609159 — cell biology — Posted on 2024-08-23

1407 PI(4)P recruits CIDE proteins to promote the formation of unilocular lipids droplets

Wu, J.; Gao, M.; Wu, X.; Liu, Y.; Du, X.; Liang, Y.; Ma, C.; Li, P.; Chen, F.-J.; Yang, H.

10.1101/2024.08.22.609036 — cell biology — Posted on 2024-08-23

1408 Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases

Ebrahim, S.; Ballesteros, A.; Zheng, W. S.; Mukherjee, S.; Hu, G.; Weng, W.-H.; Montgomery, J. W.; Agyemang, Y.; Cui, R.; Sun, W.; Krystofiak, E.; Foster, M. P.; Sotomayor, M.; Kachar, B.

10.1101/2024.08.22.609173 — cell biology — Posted on 2024-08-23

1409 Broadband high frequency Activity initializes Distractor Suppression

Schmid, P. R.; Reichert, C.; Bartsch, M.; Duerschmid, S.

10.1101/2024.08.22.609149 — neuroscience — Posted on 2024-08-23

1410 Social risk coding by amygdala activity and connectivity with dorsal anterior cingulate cortex

Kim, J.-C.; Zangemeister, L.; Tobler, P. N.; Schultz, W.; Grabenhorst, F.

10.1101/2024.08.22.608617 — neuroscience — Posted on 2024-08-23

1411 Comparing Lipinskis Rule of 5 and Machine Learning Based Prediction of Fraction Absorbed for Assessing Oral Absorption in Humans

Fagerholm, U.; Hellberg, S.; Alvarsson, J.; Ekmefjord, M.; Spjuth, O.

10.1101/2024.08.20.608791 — pharmacology and toxicology — Posted on 2024-08-23

1412 Tracking clonal evolution of drug resistance in ovarian cancer patients by exploiting structural variants in cfDNA

Williams, M. J.; Vazquez-Garcia, I.; Tam, G.; Wu, M.; Varice, N.; Havasov, E.; Shi, H.; Satas, G.; Lees, H. J.; Lee, J.; Myers, M. A.; Zatzman, M.; Rusk, N.; Ali, E.; Shah, R. H.; Berger, M. F.; Mohibullah, N.; Lakhman, Y.; Chi, D. S.; Abu-Rustum, N. R.; Aghajanian, C.; McPherson, A.; Zamarin, D.; Loomis, B.; Weigelt, B.; Friedman, C. F.; Shah, S. P.

10.1101/2024.08.21.609031 — cancer biology — Posted on 2024-08-23

1413 Predicting small-molecule inhibition of protein complexes

Yaseen, A.; Roy, S.; Akhter, N.; Ben-Hur, A.; Minhas, F.

10.1101/2024.08.23.609286 — bioinformatics — Posted on 2024-08-23

1414 Identifying novel chemical matter against the Chikungunya virus nsP3 macrodomain through crystallographic fragment screening

Aschenbrenner, J. C.; Godoy, A. S.; Fairhead, M.; Tomlinson, C. W. E.; Winokan, M.; Balcomb, B. H.; Capkin, E.; Chandran, A. V.; Golding, M.; Koekemoer, L.; Lithgo, R. M.; Marples, P. G.; Ni, X.; Thompson, W.; Wild, C.; Xavier, M.-A. E.; Fearon, D.; von Delft, F.

10.1101/2024.08.23.609196 — biochemistry — Posted on 2024-08-23

1415 Pemphigus vulgaris autoantibodies induce an ER stress response

Hoffman, C. L.; Bharathan, N. K.; Shibata, Y.; Giang, W.; Gudjonsson, J. E.; Seykora, J. T.; Prouty, S. M.; Payne, A. S.; Kowalczyk, A. P.

10.1101/2024.08.22.608849 — cell biology — Posted on 2024-08-23

1416 DNA methylation protects cancer cells against non-canonical senescence

Chen, X.; Yamaguchi, K.; Rodgers, B.; Goerhig, D.; Vindrieux, D.; Lahaye, X.; Nolot, M.; Ferry, L.; Dubus, P.; Miura, F.; Ito, T.; Manel, N.; Bernard, D.; Defossez, P.-A.

10.1101/2024.08.23.609297 — molecular biology — Posted on 2024-08-23

1417 Reply to: Eigenmodes of the brain: revisiting connectomics and geometry

Pang, J. C.; Aquino, K. M.; Oldehinkel, M.; Robinson, P. A.; Fulcher, B. D.; Breakspear, M.; Fornito, A.

10.1101/2024.08.21.608487 — neuroscience — Posted on 2024-08-23

1418 The preference for surprise in reinforcement learning underlies the differences in developmental changes in risk preference between autistic and neurotypical youth

Sumiya, M.; Katahira, K.; Akechi, H.; Senju, A.

10.1101/2024.08.23.609310 — neuroscience — Posted on 2024-08-23

1419 Exploring the uncharted: Novel potential filariasis vectors unveiled in Sri Lanka

Nimalrathna, S. U.; Amarasiri, C.; Aluthge, K.; Mallawarachchi, C.; Chandrasena, N.; de Silva, N.; de Silva, N.; Kimber, M.; Harischandra, H.

10.1101/2024.08.23.609308 — zoology — Posted on 2024-08-23

1420 Patient-derived colon epithelial organoids reveal lipid-related metabolic dysfunction in pediatric ulcerative colitis

Ojo, B. A.; Heo, L.; Fox, S. R.; Waddell, A.; Moreno-Fernandez, M. E.; Gibson, M.; Tran, T.; Dunn, A. L.; Elknawy, E. I. A.; Saini, N.; Lopez-Rivera, J. A.; Divanovic, S.; de Jesus Perez, V. A.; Rosen, M. J.

10.1101/2024.08.22.609271 — physiology — Posted on 2024-08-23

1421 Removal of the catalytic subunit of DNA-protein kinase in the proximal tubules promotes DNA and tubular damage during kidney injury

Swanson, M.; Yun, J.; Collier, D. M.; Challagundla, L.; Dogan, M.; Kuscu, C.; Garrett, M. R.; Regner, K. R.; Chung, J. H.; Park, F.

10.1101/2024.08.22.609216 — physiology — Posted on 2024-08-23

1422 Polyploid cancer cells reveal signatures of chemotherapy resistance

Schmidt, M. J.; Naghdloo, A.; Prabakar, R. K.; Kamal, M.; Cadaneanu, R.; Garraway, I. P.; Lewis, M.; Aparicio, A.; Kuhn, P.; Pienta, K. J.; Amend, S. R.; Hicks, J.

10.1101/2024.08.19.608632 — cancer biology — Posted on 2024-08-23

1423 Comment to: "Topology of molecular deformations induces triphasic catch bonding in selectin-ligand bonds"

Quapp, W.; Bofill, J. M.

10.1101/2024.08.21.608529 — biochemistry — Posted on 2024-08-23

1424 Phytochemical screening, analgesic, anti-pyretic and antibacterial potentials of Litsea glutinosa (L) leaves extracts in vivo and in vitro technique

Labu, Z.; Karim, S.; Rahman, M. T.; Hossain, M. I.; Shakil, M.

10.1101/2024.08.21.609048 — pharmacology and toxicology — Posted on 2024-08-23

1425 An extraordinary larval-like teleost fish from the Eocene of Bolca

Davesne, D.; Carnevale, G.

10.1101/2024.08.19.608581 — paleontology — Posted on 2024-08-23

1426 Habitat fragmentation enhances microbial collective defence

Verdon, N.; Popescu, O.; Titmuss, S.; Allen, R. J.

10.1101/2024.03.20.585867 — biophysics — Posted on 2024-08-23

1427 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'

Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.

10.1101/2023.11.08.566206 — ecology — Posted on 2024-08-23

1428 Expression of elongase- and desaturase-encoding genes shapes the cuticular hydrocarbon profiles of honey bees

Rodriguez-Leon, D. S.; Schmitt, T.; Pinto, M. A.; Thamm, M.; Scheiner, R.

10.1101/2024.07.22.604606 — ecology — Posted on 2024-08-23

1429 Cell swelling enhances canonical β-adrenergic signaling

Sirbu, A.; Bathe-Peters, M.; Kumar, J. L. M.; Inoue, A.; Lohse, M.; Annibale, P.

10.1101/2023.06.23.544496 — cell biology — Posted on 2024-08-23

1430 Self-association enhances early attentional selection through automatic prioritization of socially salient signals

Scheller, M.; Tunnermann, J.; Fredriksson, K.; Fang, H.; Sui, J.

10.1101/2024.07.31.605951 — neuroscience — Posted on 2024-08-23

1431 Cell Geometry and Membrane Protein Crowding Constrain Growth Rate, Overflow Metabolism, Respiration, and Maintenance Energy.

Carlson, R.; Beck, A. E.; Benitez, M.; Harcombe, W. R.; Mahadevan, K.; Gedeon, T.

10.1101/2024.08.21.609071 — systems biology — Posted on 2024-08-23

1432 Functional capacities drive recruitment of bacteria into plant root microbiota

Selten, G.; Lamouche, F.; Gomez-Repolles, A.; Blahovska, Z.; Kelly, S.; de Jonge, R.; Radutoiu, S.

10.1101/2024.08.22.609090 — plant biology — Posted on 2024-08-23

1433 The p.H222P lamin A/C mutation induces heart failure via impaired mitochondrial calcium uptake in human cardiac laminopathy

Seguret, M.; Jouve, C.; Ruiz-velasco, A.; Deshayes, L.; Guesmia, Z.; Pereira, C.; Wahbi, K.; Fauconnier, J.; Bonne, G.; Muchir, A.; Hulot, J.-S.

10.1101/2024.08.21.609073 — pathology — Posted on 2024-08-23

1434 NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion

Taghavi, A.; Chen, J. L.; Wang, Z.; Sinnadurai, K.; Salthouse, D.; Ozon, M.; Feri, A.; Fountain, M. A.; Choudhary, S.; Childs-Disney, J. L.; Disney, M. D.

10.1101/2024.08.20.608150 — biophysics — Posted on 2024-08-23

1435 GENA-LM: A Family of Open-Source Foundational DNA Language Models for Long Sequences

Fishman, V.; Kuratov, Y.; Shmelev, A.; Petrov, M.; Penzar, D.; Shepelin, D.; Chekanov, N.; Kardymon, O.; Burtsev, M.

10.1101/2023.06.12.544594 — bioinformatics — Posted on 2024-08-23

1436 SpottedPy quantifies relationships between spatial transcriptomic hotspots and uncovers new environmental cues of epithelial-mesenchymal plasticity in cancer

Withnell, E.; Secrier, M.

10.1101/2023.12.20.572627 — bioinformatics — Posted on 2024-08-23

1437 PriMAT: A robust multi-animal tracking model for primates in the wild

Vogg, R.; Nuske, M.; Weis, M. A.; Luddecke, T.; Karakoc, E.; Ahmed, Z.; Pereira, S.; Malaivijitnond, S.; Meesawat, S.; Worgotter, F.; Kappeler, P. M.; Gail, A.; Ostner, J.; Schulke, O.; Fichtel, C.; Ecker, A. S.

10.1101/2024.08.21.607881 — animal behavior and cognition — Posted on 2024-08-23

1438 Genetic basis of reproductive isolation in Torrey pine (Pinus torreyana Parry): insights from hybridization and adaptation

Di Santo, L. N.; Mead, A.; Wright, J.; Hamilton, J.

10.1101/2024.04.15.589509 — genomics — Posted on 2024-08-23

1439 Wisent genome assembly uncovers extended runs of homozygosity and a large deletion that inactivates the thyroid hormone responsive gene

Bortoluzzi, C.; Mapel, X. M.; Neuenschwander, S.; Janett, F.; Pausch, H.; Leonard, A. S.

10.1101/2024.04.08.588592 — genomics — Posted on 2024-08-23

1440 Epigenetic inheritance mediates phenotypic diversity in natural populations

Shahzad, Z.; Moore, J. D.; Choi, J.; Cassin-Ross, G.; Rouached, H.; Zilberman, D.

10.1101/2021.03.15.435374 — evolutionary biology — Posted on 2024-08-23

1441 Molecular profile, source and lineage restriction of stem cells in an annelid regeneration model

Stockinger, A. W.; Adelmann, L.; Fahrenberger, M.; Ruta, C.; Ozpolat, B. D.; Milivojev, N.; Balavoine, G.; Raible, F.

10.1101/2024.07.09.602635 — developmental biology — Posted on 2024-08-23

1442 Platelets as key cells in endometriosis patients: insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis

Bortot, B.; Di Florio, R.; Merighi, S.; Peacock, B.; Lees, R.; Valle, F.; Brucale, M.; Mangogna, A.; Di Lorenzo, G.; Romano, F.; Zito, G.; Zanconati, F.; Ricci, G.; Cancila, V.; Belmonte, B.; Biffi, S.

10.1101/2024.08.21.607595 — cell biology — Posted on 2024-08-23

1443 The Evolution of Heteroresistance via Small Colony Variants in Escherichia coli Following Long Term Exposure to Bacteriostatic Antibiotics

Gil-Gil, T.; Berryhill, B. A.; Manuel, J. A.; Smith, A. P.; Baquero, F.; Levin, B. R.

10.1101/2023.10.30.564761 — microbiology — Posted on 2024-08-23

1444 TRACKING CLONAL AND PLASMID TRANSMISSION IN COLISTIN AND CARBAPENEM RESISTANT KLEBSIELLA PNEUMONIAE

Akintayo, I.; Siroglavic, M.; Frolova, D.; Silva, M. B.; Grundmann, H.; Iqbal, Z.; Budmir, A.; Reuter, S.

10.1101/2024.08.20.608806 — microbiology — Posted on 2024-08-23

1445 Perturbation of de novo lipogenesis hinders MERS-CoV assembly and release, but not the biogenesis of viral replication organelles

Snijder, E. J.; Soultsioti, M.; de Jong, A. W. M.; Blomberg, N.; Tas, A.; Giera, M.; Barcena, M.

10.1101/2024.08.21.608937 — microbiology — Posted on 2024-08-23

1446 Loss of Insulin Signaling in Microglia Impairs Cellular Uptake of Aβ and Neuroinflammatory Response Exacerbating Alzheimer-like Neuropathology

Chen, W.; Liu, X.; Munoz, V. R.; Kahn, C. R.

10.1101/2024.08.22.609112 — neuroscience — Posted on 2024-08-23

1447 Two-brain microstates: A novel hyperscanning-EEG method for quantifying task-driven inter-brain asymmetry

Li, Q.; Zimmermann, M.; Konvalinka, I.

10.1101/2024.05.06.592342 — neuroscience — Posted on 2024-08-23

1448 Conservation of molecular responses upon viral infection in the non-vascular plant Marchantia polymorpha

Ros-Moner, E.; Jimenez-Gongora, T.; Villar-Martin, L.; Vogrinec, L.; Gonzalez-Miguel, V. M.; kutnjak, D.; Rubio-Somoza, I.

10.1101/2023.11.06.565823 — plant biology — Posted on 2024-08-23

1449 Role of microstructure of cellulosic mucilage in seed anchorage:A mechanical interpretation of antitelechory in plants

Bhaskaran, K.; Puchalapalli, S.; Deshpande, A. P.; Varughese, S.

10.1101/2024.01.08.574694 — physiology — Posted on 2024-08-23

1450 Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases

Liu, J.; Shah, A.; Ma, Y.; Hardman, K.; Johansson, N. G.; De Castro Ribeiro, O. M.; Brookfield, A.; Bowen, A.; Yli-Kauhaluoma, J.; Xhaard, H.; Jeuken, L.; Goldman, A.; Pliotas, C.; Vidilaseris, K.

10.1101/2024.07.26.605302 — biochemistry — Posted on 2024-08-23

1451 Glucokinase activity controls subpopulations of β-cells that alternately lead islet Ca2+ oscillations

Jin, E.; Briggs, J. K.; Benninger, R. K.; Merrins, M. J.

10.1101/2024.08.21.608680 — biophysics — Posted on 2024-08-23

1452 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health

10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-23

1453 Pregranulosa cells upregulate cardiac troponin I Tnni3 upon cell cycle resumption during primordial follicle activation.

Taylor, G.; Frost, E. R.; Crow, B. N.; Radley, A.; Boeing, S.; Galichet, C.; Baker, M. A.; Sutherland, J. M.; Lovell-Badge, R.

10.1101/2022.10.24.513438 — developmental biology — Posted on 2024-08-23

1454 Live-cell imaging and CLEM reveal the existence of ACTN4-dependent ruffle-edge lamellipodia acting as a novel mode of cell migration

Morishita, H.; Kawai, K.; Egami, Y.; Honda, K.; Araki, N.

10.1101/2024.05.20.594911 — cell biology — Posted on 2024-08-23

1455 Single cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes

G V S, D.; Terasaki, M.; Dani, A.

10.1101/2024.01.08.574704 — neuroscience — Posted on 2024-08-23

1456 A developmental cell atlas of the human thyroid gland

Massalha, H.; Trinh, M. K.; Armingol, E.; Tuck, L.; Predeus, A.; Mazin, P.; Sancho-Serra, C.; Oszlanczi, A.; Wood, Y.; Parks, C.; Ogbonnah, T.; Whitfield, H. J.; Kelava, I.; Behjati, S.; Vento-Tormo, R.; Schoenmakers, N.

10.1101/2024.08.22.609152 — genomics — Posted on 2024-08-22

1457 Capturing changes to animal complexity from quantifiable patterns in genomic data

Peterson, K. J.; Clarke, A.; Zolotarov, G.; Deline, B.; McPeek, M.; Martinez, P.; Fromm, B.

10.1101/2024.08.22.609214 — evolutionary biology — Posted on 2024-08-22

1458 Castor is a temporal transcription factor that specifies early born central complex neuron identity

Dillon, N. R.; Doe, C. Q.

10.1101/2024.08.22.609207 — developmental biology — Posted on 2024-08-22

1459 Genotype dependence of virulence-associated genes in ESBL-producing Escherichia coli isolated from the blood of patients with urinary tract infections

Tanaka, M.; Hanawa, T.; Suda, T.; Tanji, Y.; Le, M. N.; Kondo, K.; Azame, A. H.; Kiga, K.; Yonetani, S.; Yashiro, R.; Omori, T.; Matsuda, T.

10.1101/2024.08.21.608955 — microbiology — Posted on 2024-08-22

1460 The neural mechanisms of fast versus slow decision-making

Nashaat, M.; Oraby, H.; Krasniqi, F.; Goh-Sauerbier, S. T.; Bosc, M.; Koerner, S.; Karayel, S.; Kepecs, A.; Larkum, M.

10.1101/2024.08.22.608577 — neuroscience — Posted on 2024-08-22

1461 Generation of humanized mouse models to support therapeutic development for SYNGAP1 and STXBP1 disorders

Felix, A. J.; Wilson, T.; Randell, R.; Marotta, N.; Uchida, K.; Boland, M. J.; Davidson, B. L.; Prosser, B. L.

10.1101/2024.08.22.609238 — neuroscience — Posted on 2024-08-22

1462 Latent Diffusion For Conditional Generation of Molecules

Kaufman, B.; Williams, E. C.; Pederson, R.; Underkoffler, C.; Panjwani, Z.; Wang-Henderson, M.; Mardirossian, N.; Katcher, M. H.; Strater, Z.; Grandjean, J.-M.; Lee, B.; Parkhill, J.

10.1101/2024.08.22.609169 — bioinformatics — Posted on 2024-08-22

1463 Using Glittr.org to find, compare and re-use online training materials

van Geest, G.; Haefliger, Y.; Zahn-Zabal, M.; Palagi, P.

10.1101/2024.08.20.608021 — bioinformatics — Posted on 2024-08-22

1464 Replicator dynamics generalized for evolutionary matrix games under time constraints

Varga, T.

10.1101/2024.08.22.609164 — evolutionary biology — Posted on 2024-08-22

1465 Epigenetic deprogramming driven by disruption of CIZ1-RNA nuclear assemblies in early-stage breast cancers

Coverley, D.

10.1101/2024.08.22.609161 — cell biology — Posted on 2024-08-22

1466 Sex and APOE4-specific links between cardiometabolic risk factors and white matter alterations in individuals with a family history of Alzheimer's disease

Tremblay, S. A.; Spreng, R. N.; Wearn, A.; Alasmar, Z.; Pirhadi, A.; Tardif, C. L.; Chakravarty, M.; Villeneuve, S.; Leppert, I. R.; Carbonell, F.; Iturria-Medina, Y.; Steele, C. J.; Gauthier, C. J.; the PREVENT-AD Research Group,

10.1101/2024.08.21.608995 — neuroscience — Posted on 2024-08-22

1467 Speech Synthesis from Electrocorticogram During Imagined Speech Using a Transformer-Based Decoder and Pretrained Vocoder

Komeiji, S.; Shigemi, K.; Mitsuhashi, T.; Iimura, Y.; Suzuki, H.; Sugano, H.; Shinoda, K.; Yatabe, K.; Tanaka, T.

10.1101/2024.08.21.608927 — neuroscience — Posted on 2024-08-22

1468 Confinement and Catalysis Within De Novo Designed Peptide Barrels

Petrenas, R.; Hawkins, O. A.; Jones, J. F.; Scott, D. A.; Fletcher, J. M.; Obst, U.; Lombardi, L.; Pirro, F.; Leggett, G. J.; Oliver, T. A. A.; Woolfson, D. N.

10.1101/2024.08.22.609140 — synthetic biology — Posted on 2024-08-22

1469 Multi-Layer Autocatalytic Feedback Enables Integral Control Amidst Resource Competition and Across Scales

M. Zand, A.; Anastassov, S.; Frei, T.; Khammash, M.

10.1101/2024.08.22.609155 — synthetic biology — Posted on 2024-08-22

1470 Altered host pyruvate metabolism fuels and regulates fungal asexual reproduction

Lee, M. Y.; Jaenisch, J.; McRae, A. G.; Hirai-Adachi, C.; Louie, K.; Silva, L. P.; Bowen, B. P.; Northen, T. R.; Wildermuth, M. C.

10.1101/2024.08.22.609210 — plant biology — Posted on 2024-08-22

1471 Functional capacities drive recruitment of bacteria into plant root microbiota

Selten, G.; Lamouche, F.; Gomez-Repolles, A.; Blahovska, Z.; Kelly, S.; de Jonge, R.; Radutoiu, S.

10.1101/2024.08.22.609090 — plant biology — Posted on 2024-08-22

1472 Protocol for muscle fiber type and cross-sectional areaanalysis in cryosections of whole lower mouse hindlimbs

Battey, E.; Biswas, D.; Dos Santos, M.; Maire, P.; Sakamoto, K.

10.1101/2024.08.22.608909 — physiology — Posted on 2024-08-22

1473 Brewery Waste as a Sustainable Protein Source for the Banded Cricket (Gryllodes sigillatus)

Kasdorf, S. Y.; Muzzatti, M. J.; Haider, F.; Bertram, S. M.; MacMillan, H. A.

10.1101/2024.08.21.609009 — physiology — Posted on 2024-08-22

1474 Visualizing Single V-ATPase Rotation Using Janus Nanoparticles

Otomo, A.; Wiemann, J.; Bhattacharyya, S.; Yamamoto, M.; Yu, Y.; Iino, R.

10.1101/2024.08.22.609254 — biophysics — Posted on 2024-08-22

1475 Biophysical limits of ultrafast cellular motility

Chang, R.; Prakash, M.

10.1101/2024.08.22.609204 — biophysics — Posted on 2024-08-22

1476 Structural basis of phosphate export by human XPR1

He, Q.; Zhang, R.; Tury, S.; Courgnaud, V.; Liu, F.; Battini, J.-l.; Li, B.; Chen, Q.

10.1101/2024.08.22.609128 — biochemistry — Posted on 2024-08-22

1477 An NADH-controlled gatekeeper of ATP synthase

Schildhauer, F.; Ryl, P. S.; Lauer, S. M.; Lenz, S.; Barlas, A. B.; Ouzounidis, V. R.; Jeffrey, K.; Marcu, D.-C.; O'Reilly, F. J.; Graziadei, A.; Stuiver, M.; Schmidt, K.; Ewers, H.; Spahn, C. M.; Karaca, E.; Busch, K. E.; Cheerambathur, D.; Schwefel, D.; Rappsilber, J.

10.1101/2024.08.22.609182 — biochemistry — Posted on 2024-08-22

1478 Detecting genetically variant peptides in non-human samples

Chu, F.; Lin, A.

10.1101/2024.08.22.609263 — biochemistry — Posted on 2024-08-22

1479 Genomic sequence analysis of the first mpox virus detected in Kenya

Langat, S. K.; Limbaso, K. S.; Khamadi, S. A.; Nyunja, A.; Pilarowski, G.; Okunga, E.; Ofula, V.; Oluniyi, P.; Koka, H.; Koskei, E.; Owaka, S.; Chelangat, B.; Mulwa, F.; Mutisya, J.; Chepkorir, E.; Lutomiah, J.; Langat, D.; Amoth, P.; Songok, E.

10.1101/2024.08.20.608891 — genomics — Posted on 2024-08-22

1480 High-resolution Inference of Multiplexed Anti-HIV Gene Editing using Single-Cell Targeted DNA Sequencing

Bouzidi, M.; Dossani, Z.; Di Benedetto, C.; Raymond, K.; Desai, S.; Chavez, L.; Betancur, P.; Pillai, S. K.

10.1101/2024.01.24.576921 — genomics — Posted on 2024-08-22

1481 Zfp263 is a transcriptional checkpoint of neutrophil development

Devaprasad, A.; Ai, Z.; Mukherjee, A. K.; Panczel, A.; Khoyratty, T.; Ballesteros, I.; Rubio-Ponce, A.; Grinsven, E. v.; Wang, L.; Gomez, J. S.; Eames, H. L.; Hidalgo, A.; Mocsai, A.; Udalova, I. A.

10.1101/2024.08.22.609132 — genomics — Posted on 2024-08-22

1482 Sensitive and modular amplicon sequencing of Plasmodium falciparum diversity and resistance for research and public health

10.1101/2024.08.22.609145 — genomics — Posted on 2024-08-22

1483 Genomics-driven monitoring of Fraxinus latifolia (Oregon Ash) for conservation and EAB-resistance breeding

Melton, A. E.; Faske, T. M.; Sniezko, R. A.; Thibault, T.; Williams, W.; Parchman, T.; Hamilton, J. A.

10.1101/2024.08.22.609160 — genomics — Posted on 2024-08-22

1484 Variant-to-function mapping of late-onset Alzheimer's disease GWAS signals in human microglial cell models implicates RTFDC1 at the CASS4 locus

Burton, E. A.; Argenziano, M.; Cook, K.; Ridler, M.; Lu, S.; Su, C.; Manduchi, E.; Littleton, S. H.; Leonard, M. E.; Hodge, K. M.; Wang, L.-S.; Schellenberg, G. D.; Johnson, M. E.; Pahl, M. C.; Pippin, J. A.; Wells, A. D.; Anderson, S. A.; Brown, C. D.; Grant, S. F.; Chesi, A.

10.1101/2024.08.22.609230 — genetics — Posted on 2024-08-22

1485 Inhibiting EZH2 complements steroid effects in Duchenne muscular dystrophy

Jeon, E. Y.; Kwak, Y.; Kang, H.; Jin, S. Y.; Park, S.; Kim, R. G.; Ko, D.; Won, J.-K.; Cho, A.; Jung, I.; Lee, C.-H.; Park, J.; Kim, H.-Y.; Chae, J.-H.; Choi, M.

10.1101/2024.08.22.609220 — genetics — Posted on 2024-08-22

1486 The RNA binding protein Pub1 inhibits TORC1 activity in Saccharomyces cerevisiae

Orozco, H.; Matallana, E.; Molin, M.; Aranda, A.

10.1101/2024.08.22.608743 — molecular biology — Posted on 2024-08-22

1487 Endothelial MICU1 protects against vascular inflammation and atherosclerosis by inhibiting mitochondrial calcium uptake

Sun, L.; Leng, R.; He, Q.; Su, M.; Zhang, Z.; Liu, Z.; Wang, Z.; Jiang, H.; Liu, M.; Wang, L.; Huo, Y.; Miller, C. L.; Banach, M.; Huang, Y.; Evans, P. C.; Pelisek, J.; Camici, G. G.; Berk, B. C.; Offermanns, S.; Ge, J.; Xu, S.; Weng, J.

10.1101/2024.08.22.609192 — molecular biology — Posted on 2024-08-22

1488 Correlated evolutionary rates reveal novel components and cross-compartment connectivity in plant proteostasis systems

Gatts, T. C.; Rehmann, E. A.; Sloan, D. B.; Forsythe, E. S.

10.1101/2024.08.22.609246 — molecular biology — Posted on 2024-08-22

1489 Prevalence and zoonotic risk of multidrug-resistant Escherichia coli in bovine subclinical mastitis milk: Insights into the virulence and antimicrobial resistance

Chowdhury, T.; Roy, M. C.; Hossain, F. M. A.

10.1101/2024.08.22.609233 — microbiology — Posted on 2024-08-22

1490 Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity

Diaz-Salinas, M.; Chatterjee, D.; Nayrac, M.; Medjahed, H.; Prevost, J.; Pazgier, M.; Finzi, A.; Munro, J.

10.1101/2024.08.22.609179 — microbiology — Posted on 2024-08-22

1491 Genomic Epidemiology and Microevolution of the Zoonotic Pathogen Corynebacterium ulcerans

Crestani, C.; Passet, V.; Rethoret-Pasty, M.; Criscuolo, A.; Zidane, N.; Bremont, S.; Badell, E.; Brisse, S.

10.1101/2024.08.22.609154 — microbiology — Posted on 2024-08-22

1492 Potassium induces conformational changes in the Sabia virus spike complex

Cohen-Dvashi, H.; Katz, M.; Diskin, R.

10.1101/2024.08.22.609195 — microbiology — Posted on 2024-08-22

1493 Orally surface engineered probiotic system for ulcerative colitis therapy via modulating gut microbiota and immune homeostasis

Liu, J.; Fang, Z.; Zhang, X.; Chen, Y.; Kou, F.; Li, X.; Huang, L.; Yang, H.; Zheng, Y.; Huang, Y.; Wang, Y.; Qiu, X.; Ge, J.; Qian, Y.; Xing, X.-H.; Zhang, C. Y.

10.1101/2024.08.22.609086 — microbiology — Posted on 2024-08-22

1494 Prevalence and diversity of Helicobacter species in captive wild carnivores, and their implications for conservation management of endangered species

Uddin, W.; Khan, G.; Narayan, S.; Sharma, N.; Holeyachi, B. S.; Hakeem, M. A.; Siva, A. B.; Reddy, A. P.

10.1101/2024.08.22.609206 — microbiology — Posted on 2024-08-22

1495 High Throughput Repurposing Screen Reveals Compounds with Activity Against Toxoplasma gondii Bradyzoites

Uddin, T.; Xia, J.; Fu, Y.; McNamara, C. W.; Chatterjee, A. K.; Sibley, L. D.

10.1101/2024.07.01.601569 — microbiology — Posted on 2024-08-22

1496 Astrocyte extracellular matrix modulates neuronal dendritic development

Hashimoto, J. G.; Margolies, N.; Zhang, X.; Karpf, J.; Song, Y.; Davis, B. A.; Zhang, F.; Linhardt, R. J.; Carbone, L.; Guizzetti, M.

10.1101/2024.08.06.606424 — neuroscience — Posted on 2024-08-22

1497 The promise and peril of comparing fluorescence lifetime in biology revealed by simulations

Ma, P.; Sternson, S.; Chen, Y.

10.1101/2023.12.20.572686 — neuroscience — Posted on 2024-08-22

1498 δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes

Ren, H.; Li, Y.; Xie, B.; Qian, W.; Yu, Y.; Chang, T.; Yang, X.; sneppen, k.; Chen, L.; Tang, C.

10.1101/2024.08.21.608986 — systems biology — Posted on 2024-08-22

1499 Acclimation to high daily thermal amplitude converts a defense response regulator into susceptibility factor

Didelon, M.; Sucher, J.; Carvalho-Silva, P.; Zaffuto, M.; Barbacci, A.; Raffaele, S.

10.1101/2024.08.22.609129 — plant biology — Posted on 2024-08-22

1500 FUSION: A web-based application for in-depth exploration of multi-omics data with brightfield histology

Border, S.; Melo Ferreira, R.; Lucarelli, N.; Manthey, D.; Kumar, S.; Paul, A.; Mimar, S.; Naglah, A.; Cheng, Y.-H.; Barisoni, L.; Ray, J.; Strekalova, Y.; Rosenberg, A. Z.; Tomaszewski, J. E.; Hodgin, J. B.; HuBMAP consortium, ; El-Achkar, T. M.; Jain, S.; Eadon, M. T.; Sarder, P.

10.1101/2024.07.09.602778 — pathology — Posted on 2024-08-22

1501 Glucokinase activity controls subpopulations of lower case Greek beta-cells that alternately lead islet Ca2+ oscillations

Jin, E.; Briggs, J. K.; Benninger, R. K.; Merrins, M. J.

10.1101/2024.08.21.608680 — biophysics — Posted on 2024-08-22

1502 Cross-species modeling of plant genomes at single nucleotide resolution using a pre-trained DNA language model

Zhai, J.; Gokaslan, A.; Schiff, Y.; Berthel, A.; Liu, Z.-Y.; Lai, W.-Y.; Miller, Z. R.; Scheben, A.; Stitzer, M. C.; Romay, C.; Buckler, E. S.; Kuleshov, V.

10.1101/2024.06.04.596709 — bioinformatics — Posted on 2024-08-22

1503 Evidence for Interaction of 5,10-Methylenetetrahydrofolate Reductase (MTHFR) with Methylenetetrahydrofolate Dehydrogenase (MTHFD1) and General Control Nonderepressible 1 (GCN1)

Buchler, L. R.; Blomgren, L. K. M.; Burer, C.; Zanotelli, V. R. T.; Froese, D. S.

10.1101/2024.08.22.609157 — biochemistry — Posted on 2024-08-22

1504 Spatiotemporally-resolved mapping of extracellular proteomes via in vivo-compatible TyroID

Zhang, Z.; Wang, Y.; Lu, W.; Wang, X.; Guo, H.; Pan, X.; Liu, Z.; Wu, Z.; Qin, W.

10.1101/2024.08.22.609124 — biochemistry — Posted on 2024-08-22

1505 Characterization of aberrant splicing in pediatric central nervous system tumors reveals CLK1 as a candidate oncogenic dependency

Naqvi, A. S.; Corbett, R. J.; Seghal, P.; Conkrite, K. L.; Rathi, K. S.; Ennis, B. M.; Hayer, K. E.; Zhang, B.; Brown, M. A.; Miller, D. P.; Kraya, A.; Dybas, J. M.; Geng, Z.; Blackden, C.; Arif, S.; Chroni, A.; Lahiri, A.; Hollawell, M. L.; Storm, P. B.; Foster, J. B.; Koptyra, M.; Madsen, P. J.; Diskin, S. J.; Thomas-Tikhonenko, A.; Resnick, A. C.; Rokita, J. L.

10.1101/2024.08.03.606419 — genomics — Posted on 2024-08-22

1506 Biologically-informed Killer cell immunoglobulin-like receptor (KIR) gene annotation tool

Ford, M. K. B.; Hari, A.; Zhou, Q.; Numanagic, I.; Sahinalp, S. C.

10.1101/2024.08.13.607835 — genomics — Posted on 2024-08-22

1507 Performance of qpAdm-based screens for genetic admixture on admixture-graph-shaped histories and stepping-stone landscapes

Flegontova, O.; Isıldak, U.; Yüncü, E.; Williams, M. P.; Huber, C. D.; Koci, J.; Vyazov, L. A.; Changmai, P.; Flegontov, P.

10.1101/2023.04.25.538339 — genetics — Posted on 2024-08-22

1508 Temporally resolved single cell transcriptomics in a human model of amniogenesis

Sekulovski, N.; Carleton, A. E.; Rengarajan, A. A.; Lin, C.-W.; Juga, L. L.; Whorton, A. E.; Kropp Schmidt, J.; Golos, T.; Taniguchi, K.

10.1101/2023.09.07.556553 — developmental biology — Posted on 2024-08-22

1509 Identification and characterization of early human photoreceptor states and cell-state-specific retinoblastoma-related features

Shayler, D. W. H.; Stachelek, K.; Cambier, L.; Lee, S.; Bai, J.; Reid, M. W.; Weisenberger, D. J.; Bhat, B.; Aparicio, J. G.; Kim, Y.; Singh, M.; Bay, M.; Thornton, M. E.; Doyle, E. K.; Fouladian, Z.; Erberich, S. G.; Grubbs, B. H.; Bonaguidi, M. A.; Craft, C. M.; Singh, H. P.; Cobrinik, D.

10.1101/2023.02.28.530247 — developmental biology — Posted on 2024-08-22

1510 Intracellular Ebola Virus nucleocapsid assembly revealed by in situ cryo-electron tomography.

Watanabe, R.; Zyla, D.; Parekh, D.; Hong, C.; Jones, Y.; Schendel, S. L.; Wan, W.; Castillon, G.; Saphire, E. O.

10.1101/2023.12.01.569666 — microbiology — Posted on 2024-08-22

1511 Identifying representational structure in CA1 to benchmark theoretical models of cognitive mapping

Lee, J. Q.; Keinath, A. T.; Cianfarano, E.; Brandon, M. P.

10.1101/2023.10.08.561112 — neuroscience — Posted on 2024-08-22

1512 Quantifying photosynthetic restrictions

Bellasio, C.

10.1101/2024.05.24.595758 — plant biology — Posted on 2024-08-22

1513 Spatial Coherence in DNA Barcode Networks

Bonet, D. F.; Blumenthal, J. I.; Lang, S.; Dahlberg, S. K.; Hoffecker, I. T.

10.1101/2024.05.12.593725 — bioinformatics — Posted on 2024-08-22

1514 Multimodal Protein-Ligand Contrastive Pretraining for Effective and Efficient Drug Discovery

Wang, Z.; Wang, Z.; Yang, M.; Pang, L.; Nie, F.; Liu, S.; Gao, Z.; Zhao, G.; Ji, X.; Huang, D.; Zhu, Z.; Li, D.; Yuan, Y.; Zheng, H.; Zhang, L.; Ke, G.; Wang, D.; Yu, F.

10.1101/2024.08.22.609123 — bioinformatics — Posted on 2024-08-22

1515 Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging

Din, M.; Paul, S.; Ullah, S.; Yang, H.; Xu, R.-G.; Abidin, N. A. Z.; Sun, A.; Chen, Y. C.; Gao, R.; Chowdhury, B.; Zhou, F.; Rogers, S.; Miller, M.; Biswas, A.; Hu, L.; Fan, Z.; Zahner, C.; Fan, J.; Chen, Z.; Berman, M.; Xue, L.; Ju, L. A.; Chen, Y.

10.1101/2024.06.11.598290 — bioengineering — Posted on 2024-08-22

1516 Stimulative piezoelectric nanofibrous scaffolds for enhanced small extracellular vesicle production in 3D cultures

Johnston, J.; Jeon, H.; Choi, Y. Y.; Kim, G.; Shi, T.; Khong, C.; Chang, H.-C.; Myung, N. V.; Wang, Y.

10.1101/2024.04.12.589114 — bioengineering — Posted on 2024-08-22

1517 Using Repeated Lysis Steps Fractionates Between Heterotrophic and Cyanobacterial DNA Extracted from Xenic Cyanobacterial Cultures

Wagner, A. D.; Ahmed, M. M. A.; Starks, V. A.; Boudreau, P. D.

10.1101/2024.08.22.609136 — genomics — Posted on 2024-08-22

1518 NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT

Shukla, V.; Irusta, A. M.; Varberg, K. M.; Kuna, M.; Iqbal, K.; Galligos, A. M.; Aplin, J. D.; Choudhury, R. H.; Okae, H.; Arima, T.; Soares, M. J.

10.1101/2024.02.13.579974 — developmental biology — Posted on 2024-08-22

1519 Transcriptomic analysis identifies injury-responsive fibroblast populations as potential mediators of Wnt-dependent spinal cord regeneration

Alper, S. R.; Vasudevan, D.; Wheeler, M. K.; Panahi, S.; Dorsky, R.

10.1101/2024.05.17.594712 — developmental biology — Posted on 2024-08-22

1520 Immunological landscape of human lymphoid explants during measles virus infection

Acklin, J. A.; Patel, A. R.; Kurland, A. P.; Horiuchi, S.; Moss, A. S.; Degrace, E. J.; Ikegame, S.; Carmichael, J.; Kowdle, S.; Thibault, P.; Imai, N.; Ueno, H.; Tweel, B.; Johnson, J. R.; Rosenberg, B. R.; Lee, B.; Lim, J. K.

10.1101/2022.09.12.507535 — immunology — Posted on 2024-08-22

1521 Carbonic anhydrase inhibitors prevent presymptomatic capillary flow disturbances in a model of cerebral amyloidosis

Gutierrez-Jimenez, E.; Rasmussen, P. M.; Mikkelsen, I. K.; Kura, S.; Fruekilde, S. K.; Hansen, B.; Bordoni, L.; Carlsen, J.; Palmfeldt, J.; Boas, D. A.; Sakadzic, S.; Vinogradov, S. A.; El Khatib, M.; Ramos-Cejudo, J.; Wied, B.; Leduc-Galindo, D.; Canepa, E.; Mar, A. C.; Gamallo-Lana, B.; Fossati, S.; Ostergaard, L.

10.1101/2024.08.22.609091 — neuroscience — Posted on 2024-08-22

1522 What if...? Computational anatomy in the cerebellar granular layer

Gilbert, M.; Rasmussen, A.

10.1101/2023.07.14.548987 — neuroscience — Posted on 2024-08-22

1523 DNA co-methylation has a stable structure and is related to specific aspects of genome regulation

Watkins, S. H.; Suderman, M.; Hemani, G.; Burrows, K.; Lawlor, D. A.; West, J.; Willan, K.; Timpson, N. J.; Min, J.; Gaunt, T. R.

10.1101/2022.03.16.484648 — bioinformatics — Posted on 2024-08-22

1524 Cathepsin B causes trogocytosis-mediated CAR T cell dysfunction

Dietze, K. A.; Nguyen, K.; Pathni, A.; Fazekas, F.; Baker, J. M.; Gebru, E.; Wang, A.; Sun, W.; Rosati, E.; Lum, D.; Rapoport, A. P.; Fan, X.; Atanackovic, D.; Upadhyaya, A.; Luetkens, T.

10.1101/2024.06.11.598379 — bioengineering — Posted on 2024-08-22

1525 Hybrid Genome Sequence of Cryptococcus neoformans of Indian origin and comparative genome analysis

Sathiyamoorthy, J.; Ramakrishnan, J.

10.1101/2024.08.22.607543 — genomics — Posted on 2024-08-22

1526 The CALERIE™ Genomic Data Resource

Ryan, C. P.; Corcoran, D. L.; Banskota, N.; Eckstein Indik, C.; Floratos, A.; Friedman, R. A.; Kobor, M. S.; Kraus, V. B.; Kraus, W.; MacIsaac, J. L.; Orenduff, M. C.; Pieper, C. F.; White, J. P.; Ferrucci, L.; Horvath, S.; Huffman, K. M.; Belsky, D. W.

10.1101/2024.05.17.594714 — genomics — Posted on 2024-08-22

1527 Analysis of hepatic lentiviral vector transduction; implications on preclinical studies and clinical gene therapy protocols.

Kafri, T.; Zou, F.; Diering, G. H.; Hu, P.; Hao, Y.; Tang, W.

10.1101/2024.08.20.608805 — genetics — Posted on 2024-08-22

1528 Benchmarking automated detection and classification approaches for monitoring of endangered species: a case study on gibbons from Cambodia

Clink, D. J.; Cross-Jaya, H.; Kim, J.; Ahmad, A. H.; Hong, M.; Sala, R.; Birot, H.; Agger, C.; Vu, T. T.; Thi, H. N.; Chi, T. N.; Klinck, H.

10.1101/2024.08.17.608420 — ecology — Posted on 2024-08-22

1529 Conserved +1 translational frameshifting in the S. cerevisiae gene encoding YPL034W

Ivanov, I. P.; Gaikwad, S.; Hinnebusch, A. G.; Dever, T. E.

10.1101/2020.04.29.069534 — molecular biology — Posted on 2024-08-22

1530 Synaptic interactions between stellate cells and parvalbumin interneurons in layer 2 of the medial entorhinal cortex are organized at the scale of grid cell clusters

Huang, L.-W.; Garden, D. L.; McCLure, C.; Nolan, M. F.

10.1101/2023.09.18.558206 — neuroscience — Posted on 2024-08-22

1531 Disentangling signal and noise in neural responses through generative modeling

Kay, K.; Prince, J. S.; Gebhart, T.; Tuckute, G.; Zhou, J.; Naselaris, T.; Schutt, H.

10.1101/2024.04.22.590510 — neuroscience — Posted on 2024-08-22

1532 Multiple distinct timescales of rapid sensory adaptation in the thalamocortical circuit

Liew, Y. J.; Dimwamwa, E. D.; Wright, N. C.; Zhang, Y.; Stanley, G. B.

10.1101/2024.06.06.597761 — neuroscience — Posted on 2024-08-22

1533 Counting on AR: EEG responses to incongruent information with real-world context

Wimmer, M.; Pepicelli, A.; Volmer, B.; ElSayed, N.; Cunningham, A.; Thomas, B. H.; Müller-Putz, G. R.; Veas, E. E.

10.1101/2024.08.22.608951 — neuroscience — Posted on 2024-08-22

1534 A new genome-scale metabolic model of oleaginous microalgae with refined lipid metabolism elucidates Microchloropsis gaditana mutant phenotypes.

Dupont-Thibert, C.; Roy, S.; Carneiro, S.; Pereira, B.; Careira, R.; Vilaca, P.; Collin, S.; Marechal, E.; Billey, E.; Curien, G.; Durot, M.; Jouhet, J.

10.1101/2023.12.06.570374 — plant biology — Posted on 2024-08-22

1535 A deep-learning based analysis framework for ultra-high throughput screening time-series data

Balzerowski, P.; Gnutt, D.; Hebing, L.; Lima, F. d. A. e.; Manesso, E.; Mueller, T.; Diedam, H.

10.1101/2024.08.22.609110 — bioinformatics — Posted on 2024-08-22

1536 Machine learning model to predict risk assessment of a child inheriting a genetic disorder

Ramaswamy, M.; Senthilnathan, S.; Saravanan, A. R. I.; M, S.; Sivashanmugam, K.

10.1101/2024.08.22.609095 — genetics — Posted on 2024-08-22

1537 Directionality Theory and Mortality Patterns Across the Primate Lineage

Demetrius, L.; Sahasranaman, A.; Ziehe, M.

10.1101/2024.08.22.609121 — evolutionary biology — Posted on 2024-08-22

1538 Mapping the Global Distribution of Mus musculus: Implications for Evolutionary Genetics

Garretson, A. C.; Blanco-Berdugo, L. A.; Dumont, B. L.

10.1101/2024.07.09.602589 — evolutionary biology — Posted on 2024-08-22

1539 Development of Pial Collaterals by Extension of Pre-existing Artery Tips

Kumar, S.; Ghosh, S.; Shanavas, N.; Sivaramakrishnan, V.; Dwari, M.; Das, S.

10.1101/2023.12.07.570539 — developmental biology — Posted on 2024-08-22

1540 Falsifying computational models of angiogenesis through quantitative comparison with in vitro models

Vergroesen, T. M.; Vermeulen, V.; Merks, R. M. H.

10.1101/2024.08.06.606790 — developmental biology — Posted on 2024-08-22

1541 Conservation of gene expression patterns between the amniotic epithelium at birth and a newborn's nasal epithelium

Hancock, D. G.; Agudelo-Romero, P.; Kicic-Starcevich, E.; Lim, J.; Iosifidis, T.; Karpievitch, Y. V.; Zhang, G.; Martino, D. J.; Kicic, A.; Stick, S. M.

10.1101/2024.08.22.609087 — molecular biology — Posted on 2024-08-22

1542 DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue.

Farina, S.; Esposito, F.; Modafferi, S.; Brandi, O.; Di Salvio, M.; Della Valle, I.; Cicio, G.; Riccardi, A.; Pisati, F.; Garbelli, A.; D'ambrosi, N.; Cozzolino, M.; Cestra, G.; d'Adda di Fagagna, F.; Gioia, U.; Francia, S.

10.1101/2024.08.22.609115 — molecular biology — Posted on 2024-08-22

1543 Investigating the influence of iron parameters in regulating platelet recovery in Apheresis Platelet Donors

De, R.; Stephen, L.; Mathews, V.; George, B.; Edison, E. S.

10.1101/2024.08.22.609101 — molecular biology — Posted on 2024-08-22

1544 Temporal Dynamics and Adaptive Mechanisms of Microbial Communities: Divergent Responses and Network Interactions

Sun, S.; Qiao, Z.; Tikhonenkov, D. V.; Gong, Y.; Li, H.; Li, R.; Sun, K.; Huo, D.

10.1101/2024.08.22.609127 — microbiology — Posted on 2024-08-22

1545 High-quality transcriptome profile of Treponema pallidum subsp. pallidum: confirmation of transcriptional landscape

Grillova, L.; Carrami, E. M.; Roberts-Sengier, W.; Thomson, N. R.

10.1101/2024.08.22.609093 — microbiology — Posted on 2024-08-22

1546 Pangenome and Transcriptomic Analysis Revealed Distinct Virulence Genes Profiles and Infection Responses in Shigella Sonnei and Shigella Flexneri

Wong, B. C.; Wee, W. Y.; Tan, H. S.

10.1101/2024.08.22.609085 — microbiology — Posted on 2024-08-22

1547 On the relationship between serotype, chemotype and genotype for Cryptococcus spp. including a method for including polysaccharide structure in strain characterization

Wear, M. P.; Greengo, S.; McConnell, S.; Xu, A.; Lopes, L. L.; Majumdar, A.; Casadevall, A.

10.1101/2024.08.22.609096 — microbiology — Posted on 2024-08-22

1548 Activation and Evasion of the FEAR Pathway by RNA Viruses

Rex, E. A.; Seo, D.; Embry, A.; Arulanandam, R.; Spinelli, M. M.; Diallo, J.-S.; Gammon, D. B.

10.1101/2024.08.22.609092 — microbiology — Posted on 2024-08-22

1549 Indiv-Brain: Individualized Brain Network Partition Learned from Individual fMRI Data using Deep Clustering with Vertex-level Attention

Guo, Z.; Duan, Y.; Xing, L.; Zhao, X.; Long, Z.

10.1101/2024.08.22.608966 — neuroscience — Posted on 2024-08-22

1550 chrna3 modulates biphasic response to alcohol

Raine, J.; Kibat, C.; Banerjee, T. D.; Monteiro, A.; Mathuru, A.

10.1101/2024.08.22.607435 — neuroscience — Posted on 2024-08-22

1551 A cup of coffee can boost your motor performance: Enhanced motor sequence learning with caffeine

Kim, H.; Wright, D. L.; Kweon, J.; Brown, J. C.

10.1101/2024.08.22.609116 — neuroscience — Posted on 2024-08-22

1552 Sustained activity in a descending neuron is associated with flight saccades in Drosophila

Buchsbaum, E.; Schnell, B.

10.1101/2024.08.22.608914 — neuroscience — Posted on 2024-08-22

1553 Retrosplenial cortex encodes both local and global space in connected environments

Laurent, C.; Smith, D. M.; Sargolini, F.; Jacob, P.-Y.

10.1101/2024.08.22.609122 — neuroscience — Posted on 2024-08-22

1554 Terminal nucleotidyltransferase Tent2 microRNA tailing regulates excitatory/inhibitory balance in the hippocampus

Wardaszka, P.; Kuzniewska, B.; Guminska, N.; Hojka-Osinska, A.; Puchalska, M.; Milek, J.; Stawikowska, A.; Krawczyk, P.; Pauzin, F. P.; Wojtowicz, T.; Radwanska, K.; Bramham, C. R.; Dziembowski, A.; Dziembowska, M.

10.1101/2024.08.22.609125 — neuroscience — Posted on 2024-08-22

1555 Reinforcement learning of state representation and value: the power of random feedback and biological constraints

Tsurumi, T.; Kato, A.; Kumar, A.; Morita, K.

10.1101/2024.08.22.609100 — neuroscience — Posted on 2024-08-22

1556 Single neurons and networks in the claustrum integrate input from widespread cortical sources

Shelton, A. M.; Oliver, D. K.; Lazarte, I. P.; Grimstvedt, J. S.; Kapoor, I.; Swann, J. A.; Ashcroft, C. A.; Williams, S. N.; Conway, N.; Tir, S.; Robinson, A.; Peirson, S. N.; Akam, T.; Kentros, C.; Witter, M. P.; Butt, S. J.; Packer, A. M.

10.1101/2022.05.06.490864 — neuroscience — Posted on 2024-08-22

1557 Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma

Mariniello, K.; Pittaway, J. F. H.; Altieri, B.; Silva Borges, K.; Hadjidemetriou, I.; Ribeiro, C.; Ruiz-Babot, G.; Lim, J. A.; Foster, J.; Cleaver, J.; Sosabowski, J.; Rahman, N.; Doroszko, M.; Hantel, C.; Sigala, S.; Abate, A.; Tamburello, M.; Kiseljak-Vassiliades, K.; Wierman, M.; Parvanta, L.; Abdel-Aziz, T. E.; Chung, T.-T.; DiMarco, A.; Palazzo, F.; Gomez-Sanchez, C. E.; Taylor, D.; Rayner, O.; Ronchi, C. L.; Gaston-Massuet, C.; Sbiera, S.; Drake, W. M.; Rognoni, E.; Kroiss, M.; Breault, D. T.; Fassnacht, M.; Guasti, L.

10.1101/2024.08.22.609117 — cancer biology — Posted on 2024-08-22

1558 Asymmetry of acto-myosin cortices as active fluids shape cells in organoids

Guyomar, T.; Lu, L.; Hiraiwa, T.; Riveline, D.

10.1101/2024.08.22.609097 — biophysics — Posted on 2024-08-22

1559 Transient dynamics response analysis of the limb under impact loading

song, m.; Wei, J.; Zhang, L.

10.1101/2024.08.22.609134 — bioengineering — Posted on 2024-08-22

1560 Telomere-to-telomere, gap-free genome of mung beans (Vigna radiata) provides insights into domestication under structural variation

Jia, K.-H.; Li, G.; Wang, L.; Liu, M.; Wang, Z.-W.; Li, R.-Z.; Li, L.-L.; Xie, K.; Yang, Y.-Y.; Tian, R.-M.; Chen, X.; Si, Y.-J.; Zhang, X.-Y.; Song, F.-J.; Li, N.-N.

10.1101/2024.08.21.609077 — genomics — Posted on 2024-08-22

1561 Population genomics of a thermophilic cyanobacterium revealed divergence at subspecies level and possible adaptation genes

Chang, H.-Y.; Yen, H.-C.; Chu, H.-A.; Kuo, C.-H.

10.1101/2024.08.22.609105 — genomics — Posted on 2024-08-22

1562 S-adenosylmethionine metabolism buffering is regulated by glycine N-methyltransferase decrease via nuclear ubiquitin-proteasome system

Kashio, S.; Miura, M.

10.1101/2024.08.21.609067 — molecular biology — Posted on 2024-08-22

1563 A conserved opal termination codon optimizes a temperature-dependent tradeoff between protein production and processing in alphaviruses

Bhattacharya, T.; Alleman, E. M.; Noyola, A. C.; Emerman, M.; Malik, H. S.

10.1101/2024.08.21.609082 — microbiology — Posted on 2024-08-22

1564 Post-translational modifications on protein VII are important during the early stages of adenovirus infection.

Arnold, E. A.; Smith, J. R.; Leung, K.; Nguyen, D. H.; Kelnhofer-Millevolte, L. E.; Guo, M. S.; Smith, J. G.; Avgousti, D. C.

10.1101/2024.08.21.609089 — microbiology — Posted on 2024-08-22

1565 Unveiling the potato cultivars with microbiome interactive traits for sustainable agricultural production

Zhao, T.; Vink, S. N.; Jia, X.; Erban, A.; Schaarschmidt, S.; Kopka, J.; Zuther, E.; Treder, K.; Michalowska, D.; Attard, E.; Guyoneaud, R.; Elzenga, J. T. M.; Falcao Salles, J.

10.1101/2024.08.21.609084 — microbiology — Posted on 2024-08-22

1566 WHIX is a T6SS secretion domain found in polymorphic double-edged sword effectors

Fridman, C. M.; Keppel, K.; Rudenko, V.; Altuna-Alvarez, J.; Albesa-Jove, D.; Bosis, E.; Salomon, D.

10.1101/2024.08.21.608442 — microbiology — Posted on 2024-08-22

1567 Spinal Cord Injury Enhances Lung Inflammation and Exacerbates Immune Response After Acute Lung Injury

Berk, B. C.; Pereira, A.; Vizcarra, V. S.; Proschel, C.; Hsu, C. G.

10.1101/2024.08.21.608879 — immunology — Posted on 2024-08-22

1568 Vagal TRPV1+ sensory neurons regulate myeloid cell dynamics and protect against influenza virus infection

Yang, D.; Almanzar, N.; Xia, J.; Udit, S.; Yeung, S. T.; Khairallah, C.; Hoagland, D. A.; Umans, B. D.; Sarden, N.; Erdogan, O.; Baalbaki, N.; Beekmayer-Dhillon, A.; Lee, J.; Meerschaert, K. A.; Liberles, S. D.; Yipp, B. G.; Franklin, R. A.; Khanna, K. M.; Baral, P.; Haber, A. L.; Chiu, I. M.

10.1101/2024.08.21.609013 — immunology — Posted on 2024-08-22

1569 MLL1 directs gut-associated antibody responses to helminth and bacterial infections

Zhang, Y.; Chakma, C.; Kirn, A.; Zaini, A.; Farighi, R.; Xie, L.; Lopez-Urena, D.; Mileto, S.; Lyras, D.; Zaph, C.; Groom, J. R.; Good-Jacobson, K.

10.1101/2024.08.21.609083 — immunology — Posted on 2024-08-22

1570 Refinement of the Sugar Puckering Torsion Potential in the AMBER DNA Force Field

Zgarbova, M.; Sponer, J.; Jurecka, P.

10.1101/2024.08.21.609021 — biophysics — Posted on 2024-08-22

1571 Quantitative Interpretation of Transverse Spin Relaxation by Translational Diffusion in Liquids Under Arbitrary Potentials

Okuno, Y.

10.1101/2024.08.21.609078 — biophysics — Posted on 2024-08-22

1572 NeuroVar: An Open-source Tool for Gene Expression and Variation Data Visualization for Biomarkers of Neurological Diseases

Aribi, H. B.; Abassi, N.; Awe, O. I.

10.1101/2024.08.21.609056 — bioinformatics — Posted on 2024-08-22

1573 Identification and Functional Characterization of Up-Regulated Hub Genes in Adenocarcinoma Across Multiple Organ Sites

Romero, R.; Bastida, D. M. A.

10.1101/2024.08.21.609070 — bioinformatics — Posted on 2024-08-22

1574 To integrate or not to integrate: Testing degenerate strategies for solving an accumulation of perceptual evidence decision-making task

Kopec, C. D.; Luo, T. Z.; Bondy, A. G.; Gupta, D.; Elliott, V. A.; Charlton, J. A.; Breda, J. R.; Stagnaro, W. M.; Reyes, E. J.; Sirko, A. I.; Bustos, A. F.; Willock, J. M.; Morrison, J. M.; Osorio, K. L.; Brody, C. D.

10.1101/2024.08.21.609064 — animal behavior and cognition — Posted on 2024-08-22

1575 Predictive power of different Akkermansia phylogroups in clinical response to PD-1 blockade against non-small cell lung cancer

Fan, P.; Ni, M.; Fan, Y.; Ksiezarek, M.; Fan, P.

10.1101/2024.08.21.608814 — genomics — Posted on 2024-08-22

1576 The complete mitochondrial genome of Heikeopsis japonica (Decapoda: Brachyura: Dorippidae): Phylogenetic implications of the family Dorippidae

Pang, X.; Zhao, Y.; Liu, Y.; Lu, X.

10.1101/2024.08.21.609022 — genomics — Posted on 2024-08-22

1577 REDUCED CACNA1C EXPRESSION PRODUCES ANHEDONIC REACTIONS TO PALATABLE SUCROSE IN RATS: NO INTERACTIONS WITH JUVENILE OR ADULT STRESS

Gasalla, P.; Thomas, K.; Wilkinson, L.; Hall, J.; Dwyer, D. M.

10.1101/2024.08.21.608991 — genetics — Posted on 2024-08-22

1578 Distinct functions of PAXX and MRI during chromosomal end joining

Cisneros-Aguirre, M.; Lopezcolorado, F. W.; Ping, X.; Chen, R.; Stark, J. M.

10.1101/2024.08.21.607864 — genetics — Posted on 2024-08-22

1579 Clonal reproduction as a driver of liana proliferation following large-scale disturbances in temperate forests

Mori, H.; Kamijo, T.

10.1101/2024.08.21.609080 — ecology — Posted on 2024-08-22

1580 Voltage-gated calcium channels generate blastema Ca2+ fluxes restraining zebrafish fin regenerative outgrowth

Le Bleu, H. K.; Kioussi, R. G.; Henner, A. L.; Lewis, V. M.; Stewart, S.; Stankunas, K.

10.1101/2024.08.21.608903 — developmental biology — Posted on 2024-08-22

1581 Regional differences in cell characteristics in electric eel electric organs indicate electrocyte development with ventral to dorsal migration.

Senarat, S.; Matsumoto, A.; Sakaki, S.; Tsuzuki, D.; Uchida, K.; Kuwahara, M.; Hondo, E.; Iida, A.

10.1101/2024.08.21.606117 — developmental biology — Posted on 2024-08-22

1582 Epigenetic and transcriptional regulation of ovarian development altered in ErβKO ovaries

Mohamadi, R.; Vo, K.; Sharma, Y.; Mohamadi, A.; Bahadursingh, E.; Fields, P. E.; Rumi, M. A.

10.1101/2024.08.21.608994 — developmental biology — Posted on 2024-08-22

1583 FGR Src Family Kinase Causes Signaling and Phenotypic Shift Mimicking Retinoic Acid-Induced Differentiation of Leukemic Cells

Yen, A.; Kazim, N.; Yue, J.; Wang, P.

10.1101/2024.08.21.608654 — molecular biology — Posted on 2024-08-22

1584 Spatiotemporal Analysis of Lung Immune Dynamics in Lethal Coccidioides posadasii Infection

Davalos, O. A.; Sebastian, A.; Leon, N. F.; Rangel, M. V.; Miranda, N.; Murugesh, D. K.; Phillips, A. M.; Hoyer, K. K.; Hum, N. R.; Loots, G. G.; Weilhammer, D.

10.1101/2024.08.21.609002 — immunology — Posted on 2024-08-22

1585 Early immune response to Coccidioides is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation

Miranda, N.; Davalos, O. A.; Sebastian, A.; Rangel, M. V.; Leon, N. F.; Gorman, B. M.; Murugesh, D. K.; Hum, N. R.; Loots, G. G.; Hoyer, K. K.; Weilhammer, D.

10.1101/2024.08.21.609001 — immunology — Posted on 2024-08-22

1586 CARD8 inflammasome activation during HIV-1 cell-to-cell transmission

Kulsuptrakul, J.; Emerman, M.; Mitchell, P. S.

10.1101/2024.08.21.608981 — immunology — Posted on 2024-08-22

1587 A first-in-kind MAPK13 inhibitor that can correct stem cell reprogramming and post-injury disease

Zhang, Y.; Wu, K.; Mao, D.; Iberg, C. A.; Yin-Declue, H.; Sun, K.; Wikfors, H. A.; Keeler, S. P.; Li, M.; Young, D.; Yantis, J.; Crouch, E. C.; Chartock, J. R.; Han, Z.; Byers, D. E.; Brody, S. L.; Romero, A. G.; Holtzman, M. J.

10.1101/2024.08.21.608990 — immunology — Posted on 2024-08-22

1588 Keratinocyte-derived exosomes in painful diabetic neuropathy

Coy-Dibley, J.; Jayaraj, N. D.; Ren, D.; Pacifico, P.; Belmadni, A. A.; Wang, Y.-Z.; Gebis, K. K.; Savas, J. N.; Paller, A. S.; Miller, R. J.; Menichella, D. M.

10.1101/2024.08.21.608803 — neuroscience — Posted on 2024-08-22

1589 Graph models of brain state in deep anaesthesia reveal sink state dynamics of reduced spatiotemporal complexity and integration

Wilsenach, J.; Deane, C. M.; Reinert, G.; Warnaby, K.

10.1101/2024.08.21.608935 — neuroscience — Posted on 2024-08-22

1590 Coordinated cross-brain activity during accumulation of sensory evidence and decision commitment

Bondy, A. G.; Charlton, J. A.; Luo, T. Z.; Kopec, C. D.; Stagnaro, W. M.; Venditto, S. J. C.; Lynch, L.; Janarthanan, S.; Oline, S. N.; Harris, T. D.; Brody, C. D.

10.1101/2024.08.21.609044 — neuroscience — Posted on 2024-08-22

1591 Histone deacetylase inhibition expands cellular proteostasis repertoires to enhance neuronal stress resilience

Taylor, C. A.; Maor-Nof, M.; Metzl-Raz, E.; Hidalgo, A.; Yee, C.; Gitler, A. D.; Shen, K.

10.1101/2024.08.21.608176 — neuroscience — Posted on 2024-08-22

1592 ActSort: An active-learning accelerated cell sorting algorithm for large-scale calcium imaging datasets

Jiang, Y.; Akengin, H. O.; Zhou, J.; Aslihak, M. A.; Li, Y.; Hernandez, O.; Ebrahimi, S.; Zhang, Y.; Inan, H.; Jaidar, O.; Miranda, C.; Dinc, F.; Blanco-Pozo, M.; Schnitzer, M. J.

10.1101/2024.08.21.609011 — neuroscience — Posted on 2024-08-22

1593 An autonomous robotic system for high-throughput phenotyping and behavioral studies of individual fruit flies

Woo, S. J.; Huang, C.; Savall, J.; Conrad, B. L.; Luo, J.; Schnitzer, M. J.

10.1101/2024.08.21.607451 — neuroscience — Posted on 2024-08-22

1594 Deep inverse modeling reveals dynamic-dependent invariances in neural circuit mechanisms

Gao, R.; Deistler, M.; Schulz, A.; Goncalves, P. J.; Macke, J. H.

10.1101/2024.08.21.608969 — neuroscience — Posted on 2024-08-22

1595 Changing air density affects flight costs in low-flying birds

Shepard, E. L. C.; Garde, B.; Krishnan, K.; Fell, A.; Tataya, V.; Jones, C. G.; Cole, N. C.; Lempidakis, E.

10.1101/2024.08.21.608961 — zoology — Posted on 2024-08-22

1596 δ-α cell-to-cell interactions modulate pancreatic islet Ca2+ oscillation modes

Tang, C.; Ren, H.; Li, Y.; Xie, B.; Qian, W.; Yu, Y.; Chang, T.; Yang, X.; sneppen, k.; Chen, L.

10.1101/2024.08.21.608986 — systems biology — Posted on 2024-08-22

1597 Stress responses and dynamic equilibrium: Key determinants of aging in the C. elegans clk-1 mutant

Carracedo-Gonzalez, J.; Arellano-Carbajal, F.; Garrido, E.; Alvarez-Martinez, R.

10.1101/2024.08.21.609027 — systems biology — Posted on 2024-08-22

1598 Divergent Immediate and Delayed Effects of Juvenile Exposure to Doxorubicin on the Thymus in C57BL/6 Mice

George, B.; Dahlquist, K. J. V.; Grant, M. K. O.; Daniel, M. R.; Smith, D. M.; Sadak, K. T.; Seelig, D.; Camell, C. D.; Zordoky, B. N.

10.1101/2024.08.21.609003 — pharmacology and toxicology — Posted on 2024-08-22

1599 Direct detection of endogenous Gαi activity in cells with a sensitive conformational biosensor

Luebbers, A.; Janicot, R.; Zhao, J.; Philibert, C. E.; Garcia-Marcos, M.

10.1101/2024.08.21.609006 — pharmacology and toxicology — Posted on 2024-08-22

1600 Spatial pattern formation of bacterial colonies with social antibiotic resistance

Denk-Lobnig, M. K.; Wood, K. B.

10.1101/2024.08.21.608973 — biophysics — Posted on 2024-08-22

1601 DeepPWM-BindingNet: Unleashing Binding Predictionwith Combined Sequence and PWM Features

Ali, S.; Chourasia, P.; Patterson, M.

10.1101/2024.08.21.609040 — bioinformatics — Posted on 2024-08-22

1602 Predicting peptide properties from mass spectrometry data using deep attention-based multitask network and uncertainty quantification

Tariq, U.; Saeed, F.

10.1101/2024.08.21.609035 — bioinformatics — Posted on 2024-08-22

1603 Enhanced Maturity and Functionality of Vascularized Human Liver Organoids through 3D Bioprinting and Pillar Plate Culture

Lekkala, V. K. R.; Shrestha, S.; Al Qaryoute, A.; Dhinoja, S.; Acharya, P.; Raheem, A.; Jagadeeswaran, P.; Lee, M.-Y.

10.1101/2024.08.21.608997 — bioengineering — Posted on 2024-08-22

1604 Facial and body colouration are linked to social rank in the African cichlid, Astatotilapia burtoni

Peros, M.; Chang, A.; Martashvili, A.; Alvarado, S. G.

10.1101/2024.08.21.608989 — animal behavior and cognition — Posted on 2024-08-22

1605 Genomic Characterization of a Dog-Mediated Rabies Outbreak in El Pedregal, Arequipa, Peru

Salazar, R.; Brunker, K.; Diaz, E. W.; Zegarra, E.; Monroy, Y.; Baldarrago, G. N.; Borrini-Mayori, K.; De la Puente-Leon, M.; Kasaragod, S.; Levy, M. Z.; Hampson, K.; Castillo-Neyra, R.

10.1101/2024.08.21.608982 — genomics — Posted on 2024-08-22

1606 Insecticide resistance and population structure of the invasive malaria vector, Anopheles stephensi, from Fiq, Ethiopia

Samake, J. N.; Yared, S.; Hassen, M. A.; Zohdy, S.; Carter, T. E.

10.1101/2024.08.21.609030 — evolutionary biology — Posted on 2024-08-22

1607 Multi-scale dynamics influence the division potential of stomatal lineage ground cells in Arabidopsis

Fung, H. F.; Amador, G. O.; Dale, R.; Gong, Y.; Vollbrecht, M.; Erberich, J. M.; Mair, A.; Bergmann, D. C.

10.1101/2024.08.21.609020 — developmental biology — Posted on 2024-08-22

1608 Cyclin C Promotes Pancreatic Development and Suppresses Cancer Initiation Through Maintenance of the Autophagy-Lysosome Pathway

Hanley, S. E.; Cai, K. Q.; Willis, S. D.; Stieg, D. C.; Klein Szanto, A. J.; Campbell, K. S.; Strich, R.

10.1101/2024.08.21.609015 — developmental biology — Posted on 2024-08-22

1609 Physiological barriers for glucose utilization in Methanosarcina acetivorans

Sattler, C.; Richter, M.; Rother, M.

10.1101/2024.08.21.609014 — microbiology — Posted on 2024-08-22

1610 Olfactory receptor coexpression and co-option in the dengue mosquito

Adavi, E. D.; dos Anjos, V. L.; Kotb, S.; Metz, H. C.; Tian, D.; Zhao, Z.; Zung, J. L.; Rose, N. H.; McBride, C. S.

10.1101/2024.08.21.608847 — neuroscience — Posted on 2024-08-22

1611 A molecular brain atlas reveals cellular shifts during the repair phase of stroke

Weber, R. Z.; Achon Buil, B.; Rentsch, N. H.; Bosworth, A.; Zhang, M.; Kisler, K.; Tackenberg, C.; Zlokovic, B. V.; Rust, R.

10.1101/2024.08.21.608971 — neuroscience — Posted on 2024-08-22

1612 Type-B response regulators MaRR_B9 and MaRR_B12 coordinate cytokinin-mediated negative regulation of anthocyanin biosynthesis in banana fruits

Rajput, R.; Tyagi, S.; Anchal, K.; Singh, S.; Laxmi, A.; Misra, P.; Pandey, A.

10.1101/2024.08.21.608915 — plant biology — Posted on 2024-08-22

1613 Investigating the impact of the interstitial fluid flow and hypoxia interface on cancer biology using a spheroid-on-chip perfusion system

Pyne, E.; Reardon, M.; Christensen, M.; Rodriguez-Mateos, P.; Taylor, S.; Iles, A.; Choudhury, A.; Pamme, N. M.; Pires, I. M.

10.1101/2024.08.21.608919 — cancer biology — Posted on 2024-08-22

1614 Integration of expression datasets to identify biomarkers for accurate Gleason scoring in Prostate Cancer

Matos-Filipe, P.; Oliva, B.; Farres, J.; Manuel Mas, J.

10.1101/2024.08.21.608965 — cancer biology — Posted on 2024-08-22

1615 Anti-correlation of LacI association and dissociation rates observed in living cells

Kandavalli, V.; Zikrin, S.; Elf, J.; Jones, D.

10.1101/2024.08.21.608596 — biophysics — Posted on 2024-08-22

1616 Investigation of pair-wise single-cell interactions by statistically interpreting spatial cell state correlation learned by self-supervised graph inductive bias transformer

Xiao, X.

10.1101/2024.08.21.608964 — bioinformatics — Posted on 2024-08-22

1617 diffGEK: Differential Gene Expression Kinetics

Barile, M.; Chabra, S.; Isobe, T.; Gottgens, B.

10.1101/2024.08.21.608952 — bioinformatics — Posted on 2024-08-22

1618 Ultra-Sensitive Detection of Transposon Insertions Across Multiple Families by Transposable Element Display Sequencing

Vendrell-Mir, P.; Leduque, B.; Quadrana, L.

10.1101/2024.08.21.608910 — genomics — Posted on 2024-08-22

1619 Ex vivo Model of Functioning Human Lymph Node Reveals Pivotal Role for Innate Lymphoid Cells and Stromal Populations in Response to Vaccine Adjuvant

Fergusson, J.; Siu, J.; Gupta, N.; Nee, E.; Reinke, S.; Stroebel, T.; Bhalla, A.; Kandage, S.; Courant, T.; Hill, S.; Attar, M.; Gordon-Weeks, A.; Coles, M.; Dendrou, C.; Milicic, A.

10.1101/2024.08.21.608943 — immunology — Posted on 2024-08-22

1620 Reverse-breaking CFS (rev-bCFS): Disentangling conscious and unconscious effects by measuring suppression and dominance times during continuous flash suppression

Ciorli, T.; Pia, L.; Stein, T.

10.1101/2024.08.21.608242 — neuroscience — Posted on 2024-08-22

1621 Cortical Excitability is Affected by Light Exposure- Distinct Effects in Adolescents and Young Adults

Sharifpour, R.; Balda Aizpurua, F.; Paparella, I.; Read, J.; Leysens, Z.; Letot, S.; Campbell, I.; Beckers, E.; Collette, F.; Phillips, C.; Zubkov, M.; Vandewalle, G.

10.1101/2024.08.21.608922 — neuroscience — Posted on 2024-08-22

1622 Neural Adaptation to the Eye's Optics Through Phase Compensation

Barbot, A.; Pirog, J. T.; Ng, C. J.; Yoon, G.

10.1101/2024.08.21.608968 — neuroscience — Posted on 2024-08-22

1623 Social 'envirotyping' the ABCD study contextualizes dissociable brain organization and diverging outcomes

Merritt, H.; Koch, M. K.; Jo, Y.; Chumin, E. J.; Betzel, R. F.

10.1101/2024.08.20.608873 — neuroscience — Posted on 2024-08-22

1624 A fluorophore-ligand conjugate for the rapid and reversible staining of native AMPA receptors in living neurons

Soga, K.; Fujiwara, T.; Nakagawa, M.; Shibata, A.; Adriel, H.; Yatsuzuka, K.; Kakegawa, W.; Yuzaki, M.; Hamachi, I.; Nango, E.; Kiyonaka, S.

10.1101/2024.08.21.608930 — neuroscience — Posted on 2024-08-22

1625 Inflammatory Signatures of Microglia in the Mouse Model of Corticosterone-Induced Depression

Zhao, Y.; Huang, Y.; Cao, Y.; Yang, J.

10.1101/2024.08.21.608928 — neuroscience — Posted on 2024-08-22

1626 LEAF SHAPE OF QUINOA WILD ANCESTOR CHENOPODIUM HIRCINUM IN A GEOGRAPHIC CONTEXT

Curti, R. N.; Rodriguez, J.; Ortega-Baes, P.; Bramardi, S. J.; Jellen, E.; Jarvis, D. E.; Maughan, P. J.; Tester, M.; Bertero, D.

10.1101/2024.08.21.608958 — plant biology — Posted on 2024-08-22

1627 Stabilized marker gene identification and functional annotation from single-cell transcriptomic data

Acharya, S.; Kossinna, P.; Zhang, Q.; GUO, J.

10.1101/2024.08.21.608838 — bioinformatics — Posted on 2024-08-22

1628 Discovery of Novel R-Selective Aminotransferase Motifs through Computational Screening

Runthala, A.; Satya Sri, P. S.; Nair, A. S.; Puttagunta, M. K.; Sekhar Rao, T. C.; Sreya, V.; Sowmya, G. R.; Reddy G, K.

10.1101/2024.08.21.608959 — bioinformatics — Posted on 2024-08-22

1629 Compartmentalized sesquiterpenoid biosynthesis and functionalization in the Chlamydomonas reinhardtii plastid

Gutierrez, S.; Overmans, S.; Wellman, G. B.; Lauersen, K. J.

10.1101/2024.08.21.608953 — bioengineering — Posted on 2024-08-22

1630 Variant-specific priors in colocalisation analysis

Pullin, J. M.; Wallace, C.

10.1101/2024.08.21.608957 — genetics — Posted on 2024-08-22

1631 Genomes of the Caribbean reef-building corals Colpophyllia natans, Dendrogyra cylindrus, and Siderastrea siderea

Locatelli, N. S.; Baums, I. B.

10.1101/2024.08.21.608299 — evolutionary biology — Posted on 2024-08-22

1632 Quantifying the seasonal reproductive cycle in three species of Malagasy fruit bats with implications for pathogen and population dynamics

Cornelius Ruhs, E.; Kettenburg, G.; Andrianiaina, A.; Andry, S.; Ranaivoson, H. C.; Grewe, F.; Brook, C. E.

10.1101/2024.08.21.608949 — ecology — Posted on 2024-08-22

1633 Common to rare transfer learning (CORAL) enables inference and prediction for a quarter million rare Malagasy arthropods

Ovaskainen, O.; Winter, S.; Tikhonov, G.; Abrego, N.; Anslan, S.; deWaard, J. R.; deWaard, S. L.; Fisher, B. L.; Furneaux, B.; Hardwick, B.; Kerdraon, D.; Pentinsaari, M.; Raharinjanahary, D.; Rajoelison, E. T.; Ratnasingham, S.; Somervuo, P.; Sones, J. E.; Zakharov, E. V.; Hebert, P. D. N.; Roslin, T.; Dunson, D.

10.1101/2024.08.21.608960 — ecology — Posted on 2024-08-22

1634 The transcription factor BATF pioneers the differentiation program of cytolytic effector CD8+ T cells through the direct interaction with IRF4

Fujisawa, S.; Tanabe, Y.; Hojo, A.; Shiga, R.; Kurachi, J.; Koura, M.; Tamai, T.; Miyanari, Y.; Wherry, E. J.; Kurachi, M.

10.1101/2024.08.21.605975 — immunology — Posted on 2024-08-22

1635 Strategies for Mitigating Impacts to Aerofauna from Offshore Wind Energy Development: Available Evidence and Data Gaps

Gulka, J.; Knapp, S.; Soccorsi, A.; Avery-Gomm, S.; Knaga, P.; Williams, K. A.

10.1101/2024.08.20.608845 — ecology — Posted on 2024-08-22

1636 Ecological factors that drive microbial communities in culturally diverse fermented foods

Gautam, A.; Poopalarajah, R.; Ahmad, A. R.; Rana, B.; Denekew, T. W.; Anh, N.; Utenova, L.; Kunwar, Y. S.; Bhandari, N. N.; Jha, A. R.

10.1101/2024.08.20.608727 — microbiology — Posted on 2024-08-22

1637 Cell-free screening, production and animal testing of a STI-related chlamydial major outer membrane protein supported in nanolipoproteins.

Mohagheghi, M. V.; Abisoye-Ogunniyan, A.; Evans, A. C.; Peterson, A. E.; Bude, G. A.; Hoang-Phou, S.; Hall, D.; Rasley, A.; Fischer, N. O.; He, W.; Robinson, B. V.; Pal, S.; Slepenkin, A.; de la Maza, L. M.; Coleman, M. A.

10.1101/2024.08.20.608363 — immunology — Posted on 2024-08-22

1638 Evoked resonant neural activity outperforms spectral markers in decoding sleep from the subthalamic nucleus

Wiest, C.; Simpson, T. G.; Pogosyan, A.; Hasegawa, H.; He, S.; Plazas, F. R.; Wehmeyer, L.; Yassine, S.; Guo, X.; Shah, R.; Merla, A.; Perera, A.; Raslan, A.; O'Keeffe, A.; Hart, M.; Morgante, F.; Pereira, E.; Askan, K.; Tan, H.

10.1101/2024.08.20.608562 — neuroscience — Posted on 2024-08-22

1639 Development of the Follow-Up Discourse Observation Protocol (FUDOP) for characterizing instructor active-learning follow-up behaviors

Cen, X.; Kight, M.; Lee, R.; Kranzfelder, P.; Lo, S. M.; Maloy, J.; Owens, M. T.

10.1101/2024.08.20.608824 — scientific communication and education — Posted on 2024-08-22

1640 WITHDRAWN: Radiation-induced non-neoplastic cells senescence promoting the proliferation and invasiveness of GBM through SASP/JAK2-STAT3 Pathway

Nie, P.; Chen, J.; Zhang, J.

10.1101/2024.02.21.581353 — cancer biology — Posted on 2024-08-22

1641 WITHDRAWN: Elephant rumble vocalizations: spectral substructures and superstructures

Rantsiou, E.

10.1101/2024.03.10.584305 — animal behavior and cognition — Posted on 2024-08-22

1642 WITHDRAWN: Rules of departure: Antiphony and personalized vocal spaces in wild male elephant group coordination

Rantsiou, E.

10.1101/2024.02.07.579388 — animal behavior and cognition — Posted on 2024-08-22

1643 High-quality genome assembly of the endemic threatened White-bellied Sholakili Sholicola albiventris (Muscicapidae: Blanford, 1868) from the Shola Sky Islands, India.

K L, V.; Arvind, C.; Goyal, N.; V.V., R.

10.1101/2024.08.20.608878 — genomics — Posted on 2024-08-22

1644 MagnoliidsGDB：An integrated functional genomics database for Magnoliids

Chen, Y.; Yang, Z.; Chen, J.; Li, P.; Zhao, X.; Huang, S.; Li, Z.; Huang, S.; Luo, J.; Hu, H.; Ding, Y.

10.1101/2024.08.19.608005 — evolutionary biology — Posted on 2024-08-22

1645 A critical reexamination of recovered SARS-CoV-2 sequencing data

Debarre, F.; Hensel, Z.

10.1101/2024.02.15.580500 — evolutionary biology — Posted on 2024-08-22

1646 The long-range gene regulatory landscape of cerebellar granule neuron progenitors

Riegman, K. L. H.; George, C.; Whittaker, D. E.; Ahmed, M. U.; Yun, H.; Huntly, B.; Sims, D.; Osborne, C. S.; Basson, M. A.

10.1101/2024.08.22.609103 — neuroscience — Posted on 2024-08-22

1647 An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality

Whitman, E. T.; Elliott, M. L.; Knodt, A. R.; Abraham, W. C.; Anderson, T. J.; Cutfield, N.; Hogan, S.; Ireland, D.; Melzer, T. R.; Ramrakha, S.; Sugden, K.; Theodore, R.; Williams, B. S.; Caspi, A.; Moffitt, T. E.; Hariri, A. R.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/2024.08.19.608305 — neuroscience — Posted on 2024-08-22

1648 Polygenic prediction and gene regulation networks

Poyatos, J. F.

10.1101/2024.05.07.592928 — systems biology — Posted on 2024-08-22

1649 Effects of Virtual Online Physical Education on Physical Fitness: Insights from a Gender Perspective in a Chinese University

Aowei, Z.; Gong, S.

10.1101/2024.08.15.608047 — physiology — Posted on 2024-08-22

1650 Confounding Fuels Misinterpretation in Human Genetics

Benning, J. W.; Carlson, J.; Smith, O.; Shaw, R.; Harpak, A.

10.1101/2023.11.01.565061 — genetics — Posted on 2024-08-22

1651 Recurrent sex chromosome turn-over in termites

Fraser, R.; Moraa, R.; Djolai, A.; Meisenheimer, N.; Laube, S.; Vicoso, B.; Huylmans, A. K.

10.1101/2024.08.12.607539 — evolutionary biology — Posted on 2024-08-22

1652 Two-way Dispatched function in Sonic hedgehog shedding and transfer to high-density lipoproteins

Ehring, K.; Ehlers, S. F.; Froese, J.; Gude, F.; Puschmann, J.; Grobe, K.

10.1101/2023.02.08.527629 — cell biology — Posted on 2024-08-22

1653 Chromatin enhancer activity of IκBα mediates the exit from naïve pluripotency

Palma, L. G.; Alvarez-Villanueva, D.; Maqueda, M.; Barrero, M.; IGLESIAS, A.; Bertran, j.; ALVAREZ, D.; GARCIA-PRIETO, C.; BALLARE, C.; RODRIGUEZ-CORTEZ, V.; BUENO, C.; VIDAL, A.; Villanueva, A.; Menendez, P.; Stik, G.; Di Croce, L.; Payer, B.; Esteller, M.; Espinosa, L.; Bigas, A.

10.1101/2023.07.28.550934 — cell biology — Posted on 2024-08-22

1654 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice

Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.

10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-08-22

1655 A whole-organism landscape of X-inactivation in humans

Gylemo, B.; Bensberg, M.; Nestor, C. E.

10.1101/2023.06.26.546519 — genetics — Posted on 2024-08-22

1656 Evolutionary change is remarkably time-independent across scales

De Lisle, S.; Svensson, E. I.

10.1101/2023.12.02.569704 — evolutionary biology — Posted on 2024-08-22

1657 A molecularly distinct cell type in the midbrain regulates intermale aggression behaviors in mice

Li, C.-Y.; Miao, C.; Ge, Y.; Wu, J.; Gao, P.; Yin, S.; Zhang, P.; Yang, H.; Tian, B.; Chen, W.; Chen, X.-Q.

10.1101/2023.10.19.562724 — neuroscience — Posted on 2024-08-22

1658 Multiple origins of dorsal ecdysial sutures in trilobites and their relatives

Du, K.-s.; Guo, J.; Losso, S.; Pates, S.; Li, M.; Chen, A.-l.

10.1101/2023.10.05.560990 — paleontology — Posted on 2024-08-22

1659 Real-time Plasmid Transmission Detection Pipeline

Scherff, N.; Rothgänger, J.; Weniger, T.; Mellmann, A.; Harmsen, D.

10.1101/2024.07.09.602722 — bioinformatics — Posted on 2024-08-22

1660 Tagging Methods for Very Small Fish

Bradley, D. D.; Schimke, E. J.; Alvey, A. P.; Hofmann, H. A.; Solomon-Lane, T. K.

10.1101/437772 — animal behavior and cognition — Posted on 2024-08-22

1661 Deciphering the variation in cuticular hydrocarbon profiles of six European honey bee subspecies

Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.

10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-08-22

1662 First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in Hydra oligactis

BOUTRY, J.; Oceane, R.; Lena, G.; Jordan, M.; Aurora, N.; Sophie, T.; Beata, U.; Rodrigo, H.; Antoine, D. M.; Jacint, T.; Frederic, T.

10.1101/2024.02.08.579507 — evolutionary biology — Posted on 2024-08-22

1663 Assessing the combined effects of forest management and climate change on carbon and water fluxes in European beech forests

Saponaro, V.; De Caceres, M.; Dalmonech, D.; D'Andrea, E.; Vangi, E.; Collalti, A.

10.1101/2024.08.20.608827 — ecology — Posted on 2024-08-22

1664 Unified Mass Imaging Maps the Lipidome of Vertebrate Development

Schede, H. H.; Haj Abdullah Alieh, L.; Rohde, L.; Hererra, A.; Schlaeppi, A.; Valentin, G.; Motlagh, A. G.; Dominguez Mantes, A. H.; Jollivet, C.; Paz Montoya, J.; Capolupo, L.; Khven, I.; Oates, A. C.; D'Angelo, G.; La Manno, G.

10.1101/2024.08.20.608739 — systems biology — Posted on 2024-08-22

1665 SwiftTCR: Efficient Computational Docking protocol of TCRpMHC-I Complexes Using Restricted Rotation Matrices

Parizi, F. M.; Aarts, Y. J. M.; Eerden, S.; Ramakrishnan, G.; Xue, L. C.

10.1101/2024.05.27.596020 — bioinformatics — Posted on 2024-08-22

1666 General encoding of canonical k-mers

Wittler, R.

10.1101/2023.03.09.531845 — bioinformatics — Posted on 2024-08-22

1667 High Resolution Outdoor Videography of Insects Using Fast Lock-On Tracking

Vo-Doan, T. T.; Titov, V. V.; Harrap, M. J.; Lochner, S.; Straw, A. D.

10.1101/2023.12.20.572558 — animal behavior and cognition — Posted on 2024-08-22

1668 Mitochondrial Dysfunction alters Early Endosome Distribution and Cargo Trafficking via ROS-Mediated Microtubule Reorganization

Vishwakarma, A.; Chikhi, L.; Todkar, K.; Ouellet, M.; Germain, M.

10.1101/2024.08.21.608999 — cell biology — Posted on 2024-08-22

1669 Platelet as key cells in endometriosis patients: insights from small extracellular vesicles in peritoneal fluid and endometriotic lesions analysis

10.1101/2024.08.21.607595 — cell biology — Posted on 2024-08-22

1670 Drosophila Clueless ribonucleoprotein particles display novel dynamics that rely on the availability of functional protein and polysome equilibrium

Hwang, H. J.; Sheard, K. M.; Cox, R. T.

10.1101/2024.08.21.609023 — cell biology — Posted on 2024-08-22

1671 Genetically encoded fluorescent sensors for visualizing polyamine levels, uptake, and distribution

Tamura, R.; Chen, J.; De Jaeger, M.; Morris, J. F.; Scott, D. A.; Vangheluwe, P.; Looger, L. L.

10.1101/2024.08.21.609037 — cell biology — Posted on 2024-08-22

1672 N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine

Wang, C.; Zhao, C.; Hu, X.; Qiang, J.; Liu, Z.; Gu, J.; Zhang, S.; Li, D.; Zhang, Y.; Burre, J.; Diao, J.; Liu, C.

10.1101/2024.03.04.583437 — biophysics — Posted on 2024-08-21

1673 Prediction Analysis of Preterm Neonates Mortality using Machine Learning Algorithms via Python Programming

Monfared, V.; Hashemi, A.

10.1101/2023.01.20.524905 — bioinformatics — Posted on 2024-08-22

1674 A stimulus-computable rational model of habituation in infants and adults

Raz, G.; Cao, A.; Saxe, R.; Frank, M. C.

10.1101/2024.08.21.609039 — animal behavior and cognition — Posted on 2024-08-21

1675 Evaluating Methods for the Prediction of Cell Type-Specific Enhancers in the Mammalian Cortex

Johansen, N. J.; Kempynck, N.; Zemke, N. R.; Somasundaram, S.; Winter, S. D.; Hooper, M.; Dwivedi, D.; Lohia, R.; Wehbe, F.; Li, B.; Abaffyova, D.; Armand, E. J.; Man, J. D.; Eksi, E. C.; Hecker, N.; Hulselmans, G.; Konstantakos, V.; Mauduit, D.; Mich, J. K.; Partel, G.; Daigle, T. L.; Levi, B. P.; Zhang, K.; Tanaka, Y.; Gillis, J.; Ting, J. T.; Ben-Simon, Y.; Miller, J.; Ecker, J. R.; Ren, B.; Aerts, S.; Lein, E. S.; Tasic, B.; Bakken, T. E.

10.1101/2024.08.21.609075 — genomics — Posted on 2024-08-21

1676 Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes

Shapiro, J. G.; Changela, N.; Jang, J. K.; Joshi, J. N.; McKim, K. S.

10.1101/2024.08.21.608908 — genetics — Posted on 2024-08-21

1677 Genotype Representation Graphs: Enabling Efficient Analysis of Biobank-Scale Data

DeHaas, D.; Pan, Z.; Wei, X.

10.1101/2024.04.23.590800 — genetics — Posted on 2024-08-21

1678 The evolution of fitness during range expansions in different dimensions

Kotsar, Y.; Matsuoka, H.; Tamiya, G.

10.1101/2023.12.29.573608 — genetics — Posted on 2024-08-21

1679 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-21

1680 Navigating "tip fog": Embracing uncertainty in tip measurements

Beaulieu, J. M.; O'Meara, B. C.

10.1101/2024.08.19.608647 — evolutionary biology — Posted on 2024-08-21

1681 Assessing the effects of female protections on size structure and spawning potential in two clawed lobster fisheries subject to varying exploitation levels

Theberge, K.; Sordalen, T. K.; Pugh, T. L.; Kindsvater, H. K.

10.1101/2024.08.05.606679 — ecology — Posted on 2024-08-22

1682 Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples

Borremans, B.; Falvo, C. A.; Crowley, D. E.; Hoegh, A.; Lloyd-Smith, J. O.; Peel, A. J.; Restif, O.; Ruiz-Aravena, M.; Plowright, R. K.

10.1101/2023.11.02.565200 — ecology — Posted on 2024-08-22

1683 Appendage regeneration requires IMPDH2 and creates a sensitized environment for enzyme filament formation

McCartney, M. E.; Wheeler, G. M.; O'Neill, A. G.; Patel, J. H.; Litt, Z. R.; Calise, S. J.; Kollman, J. M.; Wills, A. E.

10.1101/2024.07.29.605679 — developmental biology — Posted on 2024-08-21

1684 Deciphering Pre-existing and Induced 3D Genome Architecture Changes involved in Constricted Melanoma Migration

Playter, C.; Golloshi, R.; Garretson, J. H.; Gonzalez, A. R.; Olajide, T. H.; Saad, A.; Benson, S. J.; McCord, R. P.

10.1101/2024.08.21.609017 — cell biology — Posted on 2024-08-22

1685 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node

Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.

10.1101/2024.07.26.605240 — immunology — Posted on 2024-08-22

1686 Effective excitability captures network dynamics across development and phenotypes

Vinogradov, O.; Giannakakis, E.; Buendia, V.; Uysal, B.; Ron, S.; Weinreb, E.; Schwarz, N.; Lerche, H.; Moses, E.; Levina, A.

10.1101/2024.08.21.608974 — neuroscience — Posted on 2024-08-21

1687 Learning reshapes the hippocampal representation hierarchy

Chiossi, H. S. C.; Nardin, M.; Tkacik, G.; Csicsvari, J. L.

10.1101/2024.08.21.608911 — neuroscience — Posted on 2024-08-21

1688 Cellular and circuit features distinguish dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation

Dovek, L.; Marrero, K.; Zagha, E.; Santhakumar, V.

10.1101/2024.08.21.608983 — neuroscience — Posted on 2024-08-21

1689 A Hippocampal-parietal Network for Reference Frame Coordination

Zheng, Y.; Zhou, X.; Moseley, S. C.; Ragsdale, S. M.; Alday, L. J.; Wu, W.; Wilber, A. A.

10.1101/2024.08.21.609019 — neuroscience — Posted on 2024-08-21

1690 Selective direct motor cortical influence during naturalistic climbing

Koh, N.; Ma, Z.; Sarup, A.; Kristl, A. C.; Agrios, M.; Young, M.; Miri, A.

10.1101/2023.06.18.545509 — neuroscience — Posted on 2024-08-21

1691 Anatomically resolved oscillatory bursts orchestrate visual thalamocortical activity during naturalistic stimulus viewing

Meyerolbersleben, L. S.; Sirota, A.; Busse, L.

10.1101/2024.08.21.608936 — neuroscience — Posted on 2024-08-22

1692 Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex

Jamali, S.; Bagur, S.; Bremont, E.; Van Kerkoerle, T.; Dehaene, S.; Bathellier, B.

10.1101/2024.08.21.609026 — neuroscience — Posted on 2024-08-22

1693 Development and Initial Characterization of Pigs with DNAI1 Mutations and Primary Ciliary Dyskinesia

Abou Alaiwa, M. H.; Hilkin, B. M.; Price, M. P.; Gansemer, N. D.; Rector, M. R.; Stroik, M. R.; Powers, L. S.; Whitworth, K. M.; Samuel, M. S.; Jain, A.; Ostedgaard, L. S.; Ernst, S. E.; Philibert, W.; Boyken, L. D.; Moninger, T. O.; Karp, P. H.; Hornick, D. B.; Sinn, P. L.; Fischer, A. J.; Pezzulo, A. A.; McCray, P. B.; Meyerholz, D. K.; Zabner, J.; Prather, R. S.; Welsh, M. J.; Stoltz, D. A.

10.1101/2024.05.22.594822 — physiology — Posted on 2024-08-21

1694 The long noncoding RNA lnc-FANCI-2 intrinsically restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer

Liu, H.; Yu, L.; Majerciak, V.; Meyer, T.; Yi, M.; Johnson, P. F.; Cam, M.; Lowy, D. R.; Zheng, Z.-M.

10.1101/2024.02.01.578320 — cancer biology — Posted on 2024-08-21

1695 Adult male Lar gibbon sings the female great-call: A case study of inter-sex song production in a non-human primate

Varkevisser, J.; Berger, S.; van der Loo, J.; Kriengwatana, B. P.; Spierings, M.

10.1101/2024.08.21.608913 — animal behavior and cognition — Posted on 2024-08-21

1696 Octopus Hypnosis: Non-Chemical Sedation in Studying Arm-Sucker Coordination

Gribkova, E. D.; Cui, J.; Gillette, R.

10.1101/2024.04.22.590669 — animal behavior and cognition — Posted on 2024-08-21

1697 Conventional therapy induces tumor immunoediting and modulates the immune contexture in colorectal cancer

Fotakis, G.; Rieder, D.; Loncova, Z.; Carollo, S.; Klieser, E.; Neureiter, D.; Huemer, F.; Hoegler, S.; Tomberger, M.; Krogsdam, A.; Kenner, L.; Ziegler, P. K.; Greil, R.; Weiss, L.; Trajanoski, Z.

10.1101/2024.08.21.608938 — cancer biology — Posted on 2024-08-21

1698 Covalently linked adenovirus-AAV complexes as a novel platform technology for gene therapy

Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lagor, W.; Bao, G.; Lu, Z. H.; Curiel, D. T.

10.1101/2024.08.21.609008 — synthetic biology — Posted on 2024-08-21

1699 Atomic-Level Free Energy Landscape Reveals Cooperative Symport Mechanism of Melibiose Transporter

Liang, R.; Guan, L.

10.1101/2024.08.21.608993 — biophysics — Posted on 2024-08-21

1700 Unsupervised domain classification of AlphaFold2-predicted protein structures

Barone, F.; Laio, A.; Punta, M.; Cozzini, S.; Ansuini, A.; Cazzaniga, A.

10.1101/2024.08.21.608992 — bioinformatics — Posted on 2024-08-21

1701 Context-specific inhibition of mitochondrial ribosomes by phenicol and oxazolidinone antibiotics

Bibel, B.; Raskar, T.; Couvillion, M.; Lee, M.; Kleinman, J. I.; Takeuchi-Tomita, N.; Churchman, L. S.; Fraser, J. S.; Fujimori, D. G.

10.1101/2024.08.21.609012 — biochemistry — Posted on 2024-08-21

1702 Ionizable networks mediate pH-dependent allosteryin SH2 signaling proteins

Van Dyck, P. K.; Piszkin, L.; Gorski, E. A.; Tartarella Nascimento, E.; Abebe, J. A.; Hoffmann, L. M.; Peng, J. W.; White, K. A.

10.1101/2024.08.21.608875 — biochemistry — Posted on 2024-08-21

1703 Structures of Multiple Peptide Resistance Factor from Pseudomonas aeruginosa

Jha, S.; Vinothkumar, K. R.

10.1101/2024.08.21.608925 — biochemistry — Posted on 2024-08-21

1704 Impacts of nucleosome positioning elements and pre-assembled chromatin states on expression and retention of transgenes

Kwizera, R.; Xie, J.; Nurse, N. P.; Yuan, C.; Kirchmaier, A. L.

10.1101/2024.08.21.607776 — molecular biology — Posted on 2024-08-21

1705 Conserved RNA-binding protein interactions mediate syntologous lncRNA functions

Sabate-Cadenas, X.; Lavalou, P.; Ross, C. J.; Chen, L.; Zielinski, D.; Vacher, S.; Ledevin, M.; Larcher, T.; Petitjean, M.; Damy, L.; Servant, N.; Bieche, I.; Ulitsky, I.; Shkumatava, A.

10.1101/2024.08.21.605776 — molecular biology — Posted on 2024-08-21

1706 Reexamining the essentiality of Pdi1 in yeast: A PDI1 knockout is viable in Komagataella phaffii and still produces recombinant disulfide bonded proteins

Palma, A.; Kowarz, V.; Gasser, B.

10.1101/2024.08.21.609038 — microbiology — Posted on 2024-08-21

1707 Grin1Y647S/+ Mice: A Preclinical Model of GRIN1-Related Neurodevelopmental Disorder

Sullivan, M. T.; Tidball, P.; Yan, Y.; Intson, K.; Chen, W.; Xu, Y.; Venkatesan, S.; Horsfall, W.; Georgiou, J.; Finnie, P. S. B.; Lambe, E. K.; Traynelis, S. F.; Salahpour, A.; Yuan, H.; Collingridge, G. L.; Ramsey, A. J.

10.1101/2024.08.21.608984 — neuroscience — Posted on 2024-08-21

1708 Magnetic Activation of Spherical Nucleic Acids for the Remote Control of Synthetic Cells

Parkes, E.; Al Samad, A.; Mazzotti, G.; Newell, C.; Ng, B.; Radford, A.; Booth, M. J.

10.1101/2024.08.21.608917 — synthetic biology — Posted on 2024-08-21

1709 A diagnostic gap to fill: Development of molecular tools to distinguish the plant-parasitic nematode species Heterodera carotae and Heterodera cruciferae

Fouville, D.; Biget, M.; Montarry, J.; Fournet, S.; GRENIER, E.

10.1101/2024.08.21.608931 — molecular biology — Posted on 2024-08-21

1710 Fc-independent SARS-CoV-2 infection-enhancing antibodies decouple N-terminal and receptor-binding domains by cross-linking neighboring spikes

van Eerden, F. J.; Li, S.; Lusiany, T.; Ismanto, H. S.; Terada, T.; Gerle, C.; Akamatsu, K.; Hirose, M.; Sugihara, F.; Chen, D. V.; Kishikawa, J.-i.; Kato, T.; Liu, Y.; Okada, M.; Arase, H.; Standley, D. M.

10.1101/2024.08.21.608921 — molecular biology — Posted on 2024-08-21

1711 High-Intensive Interval Training Decreases Circulating HMGB1 in Insulin Resistant Patients; Plasma Lipidomics Identifies Associated Cardiometabolic Benefits

Bravo, G. M.; Paramasivam, P.; Bellissimo, G. F.; Jacquez, Q.; Zheng, H.; Amorim, F.; Alvidrez, R. I. M.

10.1101/2024.08.21.608998 — molecular biology — Posted on 2024-08-21

1712 Large serine integrases utilise scavenged phage proteins as directionality cofactors

Alsaleh, A.; Pena Reyes, T.; Baksh, A.; Taiwo-Aiyerin, O. T.; Holland, A.; Pigli, Y. Z.; Rice, P. A.; Olorunniji, F. J.

10.1101/2024.08.21.608926 — molecular biology — Posted on 2024-08-21

1713 Single-stranded DNA drives sigma subunit loading onto RNA polymerase to unlock initiation-competent conformations

Vishwakarma, R. K.; Marechal, N.; Morichaud, Z.; Blaise, M.; Margeat, E.; Brodolin, K.

10.1101/2024.08.21.608941 — molecular biology — Posted on 2024-08-21

1714 Discovery of potent SARS-CoV-2 nsp3 macrodomain inhibitors uncovers lack of translation to cellular antiviral response

Lee, A. A.; Amick, I.; Aschenbrenner, J. C.; Barr, H. A.; Benjamin, J.; Brandis, A.; Cohen, G.; Diaz-Tapia, R.; Duberstein, S.; Dixon, J.; Cousins, D.; Fairhead, M.; Fearon, D.; Frick, J.; Gayvert, J.; de Godoy, A. S.; Griffen, E. J.; Huber, K. V. M.; Koekemoer, L.; Lahav, N.; Marples, P. G.; McGovern, B. L.; Mehlman, T.; Robinson, M. C.; Singh, U.; Szommer, T.; Tomlinson, C. W. E.; Vargo, T.; von Delft, F.; Wang, S.; White, K. M.; Williams, E.; Winokan, M.

10.1101/2024.08.19.608619 — microbiology — Posted on 2024-08-21

1715 Exploring the diversity of anti-defense systems across prokaryotes, phages, and mobile genetic elements

Tesson, F.; Huiting, E.; Wei, L.; Ren, J.; Johnson, M. C.; Planel, R.; Cury, J.; Feng, Y.; Bondy-Denomy, J.; Bernheim, A.

10.1101/2024.08.21.608784 — microbiology — Posted on 2024-08-21

1716 Surfing Motility: A Novel Propulsion-Independent Mechanism for Surface Migration in Salmonella and E. coli

Panich, J.; Dudebout, E. M.; Wadhwa, N.; Blair, D. F.

10.1101/2024.08.21.609010 — microbiology — Posted on 2024-08-21

1717 Highlighting the complexity of pathogenesis: the host microbiota impacts disease development on apple fruit and is a cornerstone for its biocontrol

Sare, A. R.; Jijakli, M. H.; Massart, S.

10.1101/2024.08.21.608933 — microbiology — Posted on 2024-08-21

1718 A toolbox of FRET-based c-di-GMP biosensors and its FRET-To-Sort application for genome-wide mapping of the second messenger regulatory network

Wang, L.; Malengo, G.; Medeiros, A. S.; Chen, X.; Teteneva, N.; Gonzalez, S. S.; Hammond, M.; Sourjik, V.

10.1101/2024.08.21.609041 — microbiology — Posted on 2024-08-21

1719 Escape of SARS-CoV-2 variants KP1.1, LB.1 and KP3.3 from approved monoclonal antibodies

Planas, D.; Staropoli, I.; Planchais, C.; Yab, E.; Jeyarajah, B.; Rahou, Y.; Guivel-Benhassine, F.; Prot, M.; Lemoine, F.; Enouf, V.; Simon-Loriere, E.; Mouquet, H.; Rameix-Welti, M.-A.; Schwartz, O.

10.1101/2024.08.20.608835 — immunology — Posted on 2024-08-21

1720 Aging and viral evolution impair immunity against dominant pan-coronavirus-reactive T cell epitope

Loyal, L.; Juerchott, K.; Reimer, U.; Meyer-Arndt, L.; Henze, L.; Mages, N.; Kostrzanowski, J.; Reus, B.; Mangold, M.; Kruse, B.; Dingeldey, M.; Sawitzki, B.; Wenschuh, H.; Michel, J.; Grossegesse, M.; Nitsche, A.; Lachmann, N.; Timmermann, B.; Giesecke, C.; Braun, J.; Kern, F.; Thiel, A.

10.1101/2024.08.21.608923 — immunology — Posted on 2024-08-21

1721 The structural landscape of Microprocessor Mediated pri-let-7 miRNA processing

Garg, A.; Shang, R.; Cvetanovic, T.; Lai, E. C.; Joshua-Tor, L.

10.1101/2024.05.09.593372 — biochemistry — Posted on 2024-08-21

1722 Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity

Alharithi, Y. J.; Phillips, E. A.; Wilson, T. D.; Couvillion, S. P.; Nicora, C. D.; Darakjian, P.; Rakshe, S.; Fei, S. S.; Counts, B.; Metz, T. O.; Searles, R.; Kumar, S.; Maloyan, A.

10.1101/2024.08.20.608809 — molecular biology — Posted on 2024-08-21

1723 Distinct neuromodulatory effects of endogenous orexin and dynorphin corelease on projection-defined ventral tegmental dopamine neurons.

Mohammadkhani, A.; Qiao, M.; Borgland, S. L.

10.1101/2024.08.01.606179 — neuroscience — Posted on 2024-08-21

1724 On Human Motor Coordination: The Synergy Expansion Hypothesis

Tessari, F.; West, A. M.; Hogan, N.

10.1101/2024.04.10.588877 — neuroscience — Posted on 2024-08-21

1725 Benchmarking macaque brain gene expression for horizontal and vertical translation

Luppi, A. I.; Liu, Z.-Q. I.; Hansen, J. Y.; Cofre, R.; Kuzmin, E.; Froudist-Walsh, S.; Palomero-Gallagher, N.; Misic, B.

10.1101/2024.08.18.608440 — neuroscience — Posted on 2024-08-21

1726 Glucose Challenge Uncovers Temporal Fungibility of Metabolic Homeostasis over a day:night cycle

Malik, D. M.; Rhoades, S. D.; Zhang, S. L.; Sengupta, A.; Barber, A.; Haynes, P.; Arnadottir, E. S.; Pack, A.; Kibbey, R. G.; Kain, P.; Sehgal, A.; Weljie, A. M.

10.1101/2023.10.30.564837 — systems biology — Posted on 2024-08-21

1727 Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells

Tourneur, A.; Rodrigues Vitoria, J.; Saiselet, M.; Craciun, L.; Larsimont, D.; Lefort, A.; Libert, F.; Maenhaut, C.; Costagliola, S.; Tarabichi, M.; Romitti, M.; Detours, V.

10.1101/2024.02.15.580495 — cancer biology — Posted on 2024-08-21

1728 Interplay of condensate material properties and chromatin heterogeneity governs nuclear condensate ripening

Banerjee, D. S.; Chigumira, T.; Lackner, R. M.; Kratz, J. C.; Chenoweth, D. M.; Banerjee, S.; Zhang, H.

10.1101/2024.05.07.593010 — biophysics — Posted on 2024-08-21

1729 Cohesin distribution alone predicts chromatin organization in yeast via conserved-current loop extrusion.

Yuan, T.; Yan, H.; Li, K. C.; Surovtsev, I. V.; King, M. C.; Mochrie, S. G. J.

10.1101/2023.10.05.560890 — biophysics — Posted on 2024-08-21

1730 Adaptation to space conditions of novel bacterial species isolated from the International Space Station revealed by functional gene annotations and comparative genome analysis

SZYDLOWSKI, L. M.; Bulbul, A.; Simpson, A. C.; Kaya, D. E.; Singh, N. K.; Sezerman, U. O.; Labaj, P. P.; Kosciolek, T.; Venkateswaran, K.

10.1101/2023.09.28.559980 — bioinformatics — Posted on 2024-08-21

1731 Circulating (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood-brain barrier transport

Carecho, R.; Marques, D.; Carregosa, D.; Masuero, D.; Garcia-Aloy, M.; Tramer, F.; Passamonti, S.; Vrhovsek, U.; Ventura, R.; Brito, M. A.; Nunes dos Santos, C.; Figueira, I.

10.1101/2024.02.27.582339 — biochemistry — Posted on 2024-08-21

1732 Leveraging protein-protein interactions in phenotype prediction through graph neural networks

Smeriglio, R.; Rosell-Mirmi, J.; Radeva, P.; Abante, J.

10.1101/2024.08.13.605573 — genetics — Posted on 2024-08-21

1733 Cortical neuroprosthesis-mediated functional ipsilateral control of locomotion in rats with spinal cord hemisection

Massai, E.; Bonizzato, M.; De Jesus, I.; Drainville, R.; Martinez, M.

10.1101/2021.06.18.448959 — neuroscience — Posted on 2024-08-21

1734 Urinary Sodium Wasting and Disrupted Collecting Duct Function in Mice with dRTA-Causing SLC4A1 Mutations

Mungara, P.; MacNaughton, K.; Ullah, A. S.; Essuman, G.; Chelangarimiyandoab, F.; Mumtaz, R.; Hennings, J. C.; Hubner, C. A.; Eladari, D.; Alexander, R. T.; Cordat, E.

10.1101/2024.08.21.608692 — physiology — Posted on 2024-08-21

1735 Gender and speech material effects on the long-term average speech spectrum, including at extended high frequencies

Delaram, V.; Miller, M. K.; Ananthanarayana, R. M.; Trine, A.; Buss, E.; Stecker, G. C.; Monson, B. B.

10.1101/2024.08.21.607381 — biophysics — Posted on 2024-08-21

1736 Testing and overcoming the limitations of Modular Response Analysis

Borg, J.-P.; Colinge, J.; Ravel, P.

10.1101/2024.08.21.608972 — bioinformatics — Posted on 2024-08-21

1737 Decoding multicellular niche formation in the tumour microenvironment from nonspatial single-cell expression data

Yu, C.; Geuenich, M. J.; Ge, S.; Jang, G.-H.; Ju, T. T.; Zhang, A.; O'Kane, G.; Notta, F.; Campbell, K. R.

10.1101/2024.08.21.608956 — bioinformatics — Posted on 2024-08-21

1738 Insights from Molecular Docking and Dynamics Simulations of P2RX7-????Syn Complex

singh, K.; Joshi, J.; Sharma, S.; Irungbam, K. D.; Kumar, A.; Saini, M.; Kumar, M.

10.1101/2024.08.21.608916 — bioinformatics — Posted on 2024-08-21

1739 Capacity and limitations of microfluidic flow to increase solute transport in three-dimensional cell cultures

Bonneuil, W. V.; Katiyar, N.; Tenje, M.; Bagheri, S.

10.1101/2024.08.21.608799 — bioengineering — Posted on 2024-08-21

1740 PriMAT: A robust multi-animal tracking model for primates in the wild

10.1101/2024.08.21.607881 — animal behavior and cognition — Posted on 2024-08-21

1741 Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes

Shapiro, J. G.; Changela, N.; Jang, J. K.; Joshi, J. N.; McKim, K. S.

10.1101/2024.08.21.608908 — genetics — Posted on 2024-08-21

1742 Wolbachia introgression in Ae. aegypti is accompanied by variable loss - a multi-country assessment

Dainty, K. R.; Pacidonio, E. C.; Lee, E.; Kyrylos, P. K.; Baran, N.; Kay, E.; Dong, Y.; Pinto, S. B.; Ribeiro, G. S.; Uribe, A.; Barajas, J.; O'Neill, S. L.; Velez, I. D.; Moreira, L. A.; Simmons, C. P.; Flores, H. A.

10.1101/2024.08.21.608881 — ecology — Posted on 2024-08-21

1743 Proliferative events ameliorate DNA damage accumulation without affecting function in hematopoietic stem cells

Mehatre, S. H.; Agrawal, H.; Roy, I. M.; Schouteden, S.; Khurana, S.

10.1101/2024.08.21.608631 — cell biology — Posted on 2024-08-21

1744 Horizontal gene transfer-initiated reorganization of lipid metabolism drives lifestyle innovation in a eukaryote

Rao, B. D.; Gomez Gil, E.; Peter, M.; Balogh, G.; Nunes, V.; MacRae, J. I.; Chen, Q.; Rosenthal, P. B.; Oliferenko, S.

10.1101/2024.08.21.608818 — cell biology — Posted on 2024-08-21

1745 Characterization, enrichment, and computational modeling of cross-linked actin networks in trabecular meshwork cells

Li, H.; Harvey, D. H.; Dai, J.; Swingle, S. P.; Compton, A. M.; Sugali, C. K.; Dhamodaran, K.; Yao, J.; Lin, T.-Y.; Sulchek, T.; Kim, T.; Ethier, C. R.; Mao, W.

10.1101/2024.08.21.608970 — cell biology — Posted on 2024-08-21

1746 CD4+ but not CD8+ T cells are required for protection against severe guinea pig cytomegalovirus infections

Rollman, T. B.; Berkebile, Z. W.; Hicks, D. M.; Hatfield, J. S.; Chauhan, P.; Pravetoni, M.; Schleiss, M. R.; Milligan, G. N.; Morgan, T. K.; Bierle, C. J.

10.1101/2024.08.21.608907 — immunology — Posted on 2024-08-21

1747 Tumor suppressor p53 controls thymic NKT17 development

Celli, S.; Watanabe, M.; Hodes, R. J.

10.1101/2024.08.21.608967 — immunology — Posted on 2024-08-21

1748 Differentiable simulation enables large-scale training of detailed biophysical models of neural dynamics

Deistler, M.; Kadhim, K. L.; Pals, M.; Beck, J.; Huang, Z.; Gloeckler, M.; Lappalainen, J. K.; Schröder, C.; Berens, P.; Goncalves, P. J.; Macke, J. H.

10.1101/2024.08.21.608979 — neuroscience — Posted on 2024-08-21

1749 Spatial and morphological organization of mitochondria across a connectome

Sager, G.; Pallasdies, F. C.; Gowers, R.; Ravikumar, S.; Wu, E.; Colon-Ramos, D.; Schreiber, S.; Clark, D. A.

10.1101/2024.08.21.608912 — neuroscience — Posted on 2024-08-21

1750 Impacts of Disinfection Methods in a Granular Activated Carbon (GAC) Treatment System on Disinfected Drinking Water Toxicity and Antibiotic Resistance Induction Potential

Feng, Y.; Lau, S.; Mitch, W.; Russell, C.; Pope, G.; Gu, A. Z.

10.1101/2024.08.19.608195 — pharmacology and toxicology — Posted on 2024-08-21

1751 Effects of Release of TSG-6 from Heparin Hydrogels on Supraspinatus Muscle Regeneration

Pearson, J. J.; Mao, J.; Temenoff, J. S.

10.1101/2024.08.20.608812 — bioengineering — Posted on 2024-08-21

1752 Bases for the selection of alternate foot placement during straight- and turning-gait

Kreter, N.; Fino, P. C.

10.1101/2024.08.20.608530 — bioengineering — Posted on 2024-08-21

1753 Assessing the combined effects of forest management and climate change on carbon and water fluxes in European beech forests

Saponaro, V.; Collalti, A.; Dalmonech, D.; De Caceres, M.; D'Andrea, E.; Vangi, E.

10.1101/2024.08.20.608827 — ecology — Posted on 2024-08-21

1754 Mll4 regulates tooth enamel development

Lee, J.-M.; Jung, H.; Tang, Q.; An, W.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J.

10.1101/2024.08.20.608898 — developmental biology — Posted on 2024-08-21

1755 In utero human intestine contains maternally derived bacterial metabolites

Wang, W.; Gu, W.; Schweitzer, R.; Koren, O.; Khatib, S.; Tseng, G.; Konnikova, L.

10.1101/2024.08.20.608888 — microbiology — Posted on 2024-08-21

1756 Lipid A phosphoethanolamine transferase-mediated site-selective modifications show association with colistin resistance phenotypes and fitness

Schumann, A.; Gaballa, A.; Yang, H.; Yu, D.; Ernst, R. K.; Wiedmann, M.

10.1101/2024.08.20.608901 — microbiology — Posted on 2024-08-21

1757 Signal peptidase SpsB coordinates staphylococcal cell cycle, surface protein septal trafficking and LTA synthesis

Zhang, R.; Jia, Y.; Scaffidi, S. J.; Madsen, J. J.; Yu, W.

10.1101/2024.08.20.608893 — microbiology — Posted on 2024-08-21

1758 Flexible modeling of large-scale neural network stimulation: electrical and optical extensions to The Virtual Electrode Recording Tool for EXtracellular Potentials (VERTEX)

Pierce, A. F.; Shupe, L. E.; Fetz, E. E.; Yazdan-Shahmorad, A.

10.1101/2024.08.20.608687 — neuroscience — Posted on 2024-08-21

1759 mCLAS adaptively rescues disease-specific sleep and wake phenotypes in neurodegeneration

Dias, I.; Baumann, C. R.; Noain, D.

10.1101/2024.08.20.608757 — neuroscience — Posted on 2024-08-21

1760 Behavioral and neural correlates of diverse conditioned fear responses in male and female rats

Mitchell, J.; Vincelette, L.; Tuberman, S.; Sheppard, V.; Bergeron, E.; Calitri, R.; Clark, R.; Cody, C. R.; Kannan, A.; Keith, J.; Parakoyi, A.; Pikus, M.; Vance, V.; Ziane, L.; Brenhouse, H.; Laine, M.; Shansky, B.

10.1101/2024.08.20.608817 — neuroscience — Posted on 2024-08-21

1761 ER stress-induced TREM2 downregulation exacerbates platelet activation and myocardial infarction in patients with coronary artery disease

Wu, X.; Pan, G.; Chang, L.; Zhang, Y.; Liu, Y.; Zhang, W.; Guo, Y.; Zhang, G.; Zhong, H.; Qi, Z.; Zhang, J.; Xue, R.; Chen, S.; Hu, H.; Dong, J.; Zhang, S.; Ding, Z.

10.1101/2024.08.20.608887 — pharmacology and toxicology — Posted on 2024-08-21

1762 Identification of Antiviral Drug Candidates Against Monkeypox DNA Polymerase and Profilin-like Protein A42R Utilizing an In-Silico Approach

Amjid, M.; Khan, M. M.; Pastore, S. F.; Vincent, J. B.; Muhammad, T.

10.1101/2024.08.15.608157 — pharmacology and toxicology — Posted on 2024-08-21

1763 RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells

Spirtos, A. N.; Aljardali, M. W.; Koul, S.; Lea, J. S.; Camacho, C. V.; Kraus, W. L.

10.1101/2024.08.20.608802 — cancer biology — Posted on 2024-08-21

1764 Mathematical Modelling of Microtube-Driven Regrowth ofGlioma After Local Resection

Shyntar, A.; Hillen, T.

10.1101/2024.08.20.608880 — cancer biology — Posted on 2024-08-21

1765 Resolving interface structure and local internal mechanics of mitotic chromosomes

Ridolfi, A.; Witt, H.; Harju, J.; Clement, T. V. M.; Peterman, E.; Broedersz, C.; Wuite, G. J. L.

10.1101/2024.08.20.608279 — biophysics — Posted on 2024-08-21

1766 Refining Martini Force Field Interactions for Accurate Glycoprotein Modeling

Heidari, M.; Sikora, M.; Hummer, G.

10.1101/2024.08.20.608764 — biophysics — Posted on 2024-08-21

1767 TUSCAN: Tumor segmentation and classification analysis in spatial transcriptomics

Zang, C.; Guo, C. C.; Wei, P.; Li, Z.

10.1101/2024.08.20.608863 — bioinformatics — Posted on 2024-08-21

1768 Characterizing the role of exosomal miRNAs in metastasis

Agrawal, P.; Olgun, G.; Singh, A.; Gopalan, V.; Hannenhalli, S.

10.1101/2024.08.20.608894 — bioinformatics — Posted on 2024-08-21

1769 The Lomb-Scargle periodogram-based differentially expressed gene detection along pseudotime

Iuchi, H.; Hamada, M.

10.1101/2024.08.20.608497 — bioinformatics — Posted on 2024-08-21

1770 Understanding responses to multi-electrode epiretinal stimulation using a biophysical model

Vilkhu, R. S.; Vasireddy, P. K.; Kish, K. E.; Gogliettino, A. R.; Lotlikar, A.; Hottowy, P.; Dabrowski, W.; Sher, A.; Litke, A. M.; Mitra, S.; Chichilnisky, E. J.

10.1101/2024.08.20.608829 — bioengineering — Posted on 2024-08-21

1771 Deep Learning-driven Automatic Nuclei Segmentation of Label-free Live Cell Chromatin-sensitive Partial Wave Spectroscopic Microscopy Imaging

Gaire, S. K.; Alom, M. S.; Daneshkhah, A.; Acosta, N.; Anthony, N.; Pujadas, E.; Backman, V.

10.1101/2024.08.20.608885 — bioengineering — Posted on 2024-08-21

1772 Broad bandwidth photoacoustic imaging using a PVDF receiver array

Chandramoorthi, S.; Lopez Marin, A.; Beurskens, R.; van der Steen, A. F. W.; van Soest, G.

10.1101/2024.08.20.608753 — bioengineering — Posted on 2024-08-21

1773 OPUS-Design: Designing Protein Sequence from Backbone Structure with 3DCNN and Protein Language Model

Xu, G.; Yang, Y.; Zhang, Y.; Wang, Q.; Ma, J.

10.1101/2024.08.20.608889 — bioengineering — Posted on 2024-08-21

1774 Exogenous ECM in an environmentally-mediated in vitro model for cardiac fibrosis

Pachter, N.; Allen, K.; Hookway, T.

10.1101/2024.08.20.608840 — bioengineering — Posted on 2024-08-21

1775 An Enzyme-Linked Immunosorbent Assay (ELISA)-based Activity Assay for AMP-Activated Protein Kinase (AMPK)

Nguyen, T. P.; Liu, Y.

10.1101/2024.08.20.608877 — biochemistry — Posted on 2024-08-21

1776 Emergence of antibiotic-specific Mycobacterium tuberculosis phenotypes during prolonged treatment of mice

Wynn, E. A.; Dide-Agossou, C.; Al Mubarak, R.; Rossmassler, K.; Ektnitphong, V.; Bauman, A. A.; Massoudi, L. M.; Voskuil, M. I.; Robertson, G. T.; Moore, C. M.; Walter, N. D.

10.1101/2024.08.20.607990 — genomics — Posted on 2024-08-21

1777 A deficiency screen identifies genomic regions critical for sperm head-tail connection

Rusan, N.; Galletta, B. J.; Konstantinidou, P.; Haase, A. D.

10.1101/2024.08.20.608819 — genetics — Posted on 2024-08-21

1778 A Flexible Framework for Assessing the Cumulative Effects of Offshore Wind Energy Activities and Other Pressures on Aerofauna

Furguson, M. C.; Williams, K. A.; Goodale, M. W.; Adams, E. M.; Knaga, P.; Kingdon, K.; Avery-Gomm, S.

10.1101/2024.08.20.608171 — ecology — Posted on 2024-08-21

1779 Phthalate exposure influences mating behavior and sperm morphology in an aquatic ecotoxicology model system

Guevara, B. L.; Patel, N.; Tu, Y.; Neiman, M.

10.1101/2024.08.20.608834 — ecology — Posted on 2024-08-21

1780 Nonlinear thinking in ecology and evolution: The case for ecological scaling of the Threshold Elemental Ratio

Tumolo, B.; Olson, C.; Larson, E.; Halvorson, H.; Wagner, C. E.; Krist, A.; Osburn, F.; Moody, E.; Rock, L.; Ogbenna, U.; Wess, E.; Najev, B. L.; Pignatelli, A.; Corman, J.

10.1101/2024.08.20.608290 — ecology — Posted on 2024-08-21

1781 Morphogenic, molecular, and cellular adaptations for unidirectional airflow in the chicken lung

Gerner-Mauro, K. N.; Ellis, L. V.; Wang, G.; Nayak, R.; Lwigale, P. Y.; Poche, R. A.; Chen, J.

10.1101/2024.08.20.608866 — developmental biology — Posted on 2024-08-21

1782 The microbiota affects stem cell decision making in Hydra

He, J.; Klimovich, A.; Kock, S.; Dahmke, L.; Franzenburg, S.; Bosch, T. C. G.

10.1101/2024.08.20.608462 — developmental biology — Posted on 2024-08-21

1783 CryoSCAPE: Scalable Immune Profiling Using Cryopreserved Whole Blood for Multi-omic Single Cell and Functional Assays

Heubeck, A. T.; Phalen, C.; Kaul, N.; Wittig, P. J.; Garber, J.; Weiss, M.; Genge, P. C.; Thomson, Z.; Gustafson, C.; Reading, J.; Skene, P. J.

10.1101/2024.08.20.608826 — immunology — Posted on 2024-08-21

1784 Physical activity modifies the metabolic profile of CD4+ and CD8+ T cell subtypes at rest and upon activation in older adults

Withnall, E.; Hazeldine, J.; Llibre, A.; Duggal, N. A.; Lord, J. M.; Sardeli, A. V.

10.1101/2024.08.20.607078 — immunology — Posted on 2024-08-21

1785 Molecular Mechanisms of Coxiella burnetii Formalin Fixed Cellular Vaccine Reactogenicity Evaluated in an Established Mouse Model

Samuel, J. E.; Fratske, A. P.; Butler, S. M.; Szule, J. A.; Van Schaik, E.

10.1101/2024.08.20.608821 — immunology — Posted on 2024-08-21

1786 Transcriptional Dynamics of Sleep Deprivation and Subsequent Recovery Sleep in the Male Mouse Cortex

Popescu, A.; Ottaway, C.; Ford, K.; Patterson, T. W.; Ingiosi, A. M.; Medina, E.; Hicks, S. C.; Singletary, K.; Peixoto, L.

10.1101/2024.08.20.607983 — neuroscience — Posted on 2024-08-21

1787 Anti-NMDAR encephalitis alters intrinsic spatiotemporal coding by enhancing neuronal coupling and clustering

Rahmati, V.; Graf, J.; Ceanga, M.; Rivera, D. C.; Haselmann, H.; Liebscher, S.; Prüss, H.; Holthoff, K.; Kirmse, K.; Geis, C.

10.1101/2024.08.20.608793 — neuroscience — Posted on 2024-08-21

1788 Revisiting equivalent optical properties for cerebrospinal fluid to improve diffusion-based modeling accuracy in the brain

Lewis, A.; Fang, Q.

10.1101/2024.08.20.608859 — neuroscience — Posted on 2024-08-21

1789 Immediate TMS-EEG responses reveal motor cortex excitability

Stango, A.; Zazio, A.; Barchiesi, G.; Dognini, E.; Marcantoni, E.; Bortoletto, M.

10.1101/2024.08.20.608770 — neuroscience — Posted on 2024-08-21

1790 ANGIOTENSIN CONVERTING ENZYME HUB CAPACITY - A SIMPLE MODEL OF RELATING PEPTIDE FLUX AND RENIN INFLUENCE

Westwood, B. M.; Chappell, M. C.

10.1101/2024.08.20.608830 — systems biology — Posted on 2024-08-21

1791 Reliability of tactile perception and suppression measurements

Voudouris, D.; Georgiadis, P.; Fiehler, K.; Arikan, B. E.

10.1101/2024.08.20.608823 — physiology — Posted on 2024-08-21

1792 Optimising experimental designs for model selection of ion channel drug binding mechanisms

Patten-Elliott, F.; Lei, C. L. R.; Preston, S. P.; Wilkinson, R. D.; Mirams, G. R.

10.1101/2024.08.20.608856 — pharmacology and toxicology — Posted on 2024-08-21

1793 An in vivo screen identifies NAT10 as a master regulator of brain metastasis

Chen, J. F.; Xu, P.; Cai, W. L.; Chen, H.; Wingrove, E.; Li, W.; Biancon, G.; Zhang, M.; Balabaki, A.; Krop, E. D.; Zhang, Y.; Yin, M.; Tebaldi, T.; Meier, J. L.; Westbrook, T. F.; Halene, S.; Liu, Y.; Nguyen, D.; Yan, Q.

10.1101/2024.08.20.608711 — cancer biology — Posted on 2024-08-21

1794 Protein stability models fail to capture epistatic interactions of double point mutations

Dieckhaus, H.; Kuhlman, B.

10.1101/2024.08.20.608844 — bioinformatics — Posted on 2024-08-21

1795 CryptoBench: Cryptic protein-ligand binding sites dataset and benchmark

Skrhak, V.; Novotny, M.; Feidakis, C.; Krivak, R.; Hoksza, D.

10.1101/2024.08.20.608828 — bioinformatics — Posted on 2024-08-21

1796 haCCA: Multi-module Integrating of spatial transcriptomes and metabolomes.

Shen, X.; Zhang, X.

10.1101/2024.08.20.608773 — bioinformatics — Posted on 2024-08-21

1797 Stacked MXene/PEDOT-PSS Electrode Fiber for High-Performance Recording and Stimulation

Gou, S.; Li, P.; Yang, S.; Bi, G.; Du, Z.

10.1101/2024.08.20.608461 — bioengineering — Posted on 2024-08-21

1798 Analysis of hepatic lentiviral vector transduction; implications on preclinical studies and clinical gene therapy protocols.

Kafri, T.; Zou, F.; Diering, G. H.; Hu, P.; Hao, Y.; Tang, W.

10.1101/2024.08.20.608805 — genetics — Posted on 2024-08-21

1799 Three Open Questions in Polygenic Score Portability

Wang, J. Y.; Lin, N.; Zietz, M.; Mares, J.; Narasimhan, V. M.; Rathouz, P. J.; Harpak, A.

10.1101/2024.08.20.608703 — genetics — Posted on 2024-08-21

1800 AalpiRNA-18529 regulates vitellogenesis of Aedes albopictus via the Gadd45a-mediated JNK-dependent nurse cell apoptosis pathway

Lu, Y.; Yonghui, G.; Yulan, C.; Shuyi, R.; Yifan, G.; Peiwen, L.; Khadija, B.; Jianxia, T.; Jinbao, G.

10.1101/2024.08.20.608798 — developmental biology — Posted on 2024-08-21

1801 Extracellular Vesicle-Associated Neutrophil Elastase Activates Hepatic Stellate Cells and Promotes Liver Fibrogenesis via ERK1/2 Pathway

Oshins, R.; Greenberg, Z.; Tai, Y.-L.; Zhao, D.; Wang, X.; Mehrad, B.; He, M.; Patel, I.; Khartabil, L.; Zhou, H.; Brantly, M.; Khodayari, N.

10.1101/2024.08.20.608832 — cell biology — Posted on 2024-08-21

1802 Data acquisition strategies to reduce cardiac-induced noise in brain maps of R2* and magnetic susceptibility

Raynaud, Q.; Dardano, T.; Oliveira, R.; Di Domenicantonio, G.; Tobias, T.; Roy, C. W.; van Heeswijk, R. B.; Lutti, A.

10.1101/2024.08.20.608759 — neuroscience — Posted on 2024-08-21

1803 Evidence for belief updating in decision-variable space: past decisions with finer granularity attract future ones more strongly

Lee, H.; Lim, J.; Lee, S.-H.

10.1101/2024.08.20.608767 — neuroscience — Posted on 2024-08-21

1804 Investigating the role of axonal localization of sex peptide receptor in post-mating responses of female Drosophila melanogaster

Zhang, T.; Zhou, X.; Kim, W. J.

10.1101/2024.08.20.608772 — neuroscience — Posted on 2024-08-21

1805 Neural dynamics of visual streams interactions during memory-guided actions investigated by intracranial EEG

Moraresku, S.; Hammer, J.; Dimakopoulos, V.; Kajsova, M.; Janca, R.; Jezdik, P.; Kalina, A.; Marusic, P.; Vlcek, K.

10.1101/2024.08.20.608807 — neuroscience — Posted on 2024-08-21

1806 EEG Biomarkers of Age-Related Memory Change

Broitman, A. W.; Healey, M. K.; Kahana, M. J.

10.1101/2024.08.20.608804 — neuroscience — Posted on 2024-08-21

1807 Unified Mass Imaging Maps the Lipidome of Vertebrate Development

10.1101/2024.08.20.608739 — systems biology — Posted on 2024-08-21

1808 Minipuberty regulates reproductive lifespan and ovarian follicular loss in a mouse model with reduced minipubertal gonadotropin levels

Chester, M.; Devillers, M. M.; Corre, R.; Giton, F.; Souare, F.; Petrovic, C.-H.; Airaud, E.; Quintas, D.; Mhouty-Kodja, S.; Naule, L.; Guigon, C. J.

10.1101/2024.08.20.608775 — physiology — Posted on 2024-08-21

1809 Low extracellular pH protects cancer cells from ammonia toxicity.

Mejlvang, J.; Dravecka, M.; Mikkola, I.; Johansen, T.; Seternes, O. M.

10.1101/2024.08.20.608758 — cancer biology — Posted on 2024-08-21

1810 Genetic underpinnings of predicted changes in cardiovascular function using self supervised learning

Levine, Z.; Lutsker, G.; Godneva, A.; Weinberger, A.; Lotan-Pompan, M.; Talmor-Barkan, Y.; Reisner, Y.; Rossman, H.; Segal, E.

10.1101/2024.08.15.608061 — systems biology — Posted on 2024-08-21

1811 Enabling Transparent Toxicokinetic Modeling for Public Health Risk Assessment

Davidson-Fritz, S. E.; Ring, C. L.; Schacht, C. M.; Evans, M. V.; Chang, X.; Breen, M.; Honda, G. S.; Kenyon, E.; Linakis, M. W.; Meade, A.; Pearce, R. G.; Sfeir, M. A.; Sluka, J. P.; Devito, M. J.; Wambaugh, J. F.

10.1101/2024.08.19.608571 — pharmacology and toxicology — Posted on 2024-08-21

1812 High-Performance Classification of Breast CancerHistopathological Images Using Fine-TunedVision Transformers on the BreakHis Dataset

Gella, V.

10.1101/2024.08.17.608410 — bioinformatics — Posted on 2024-08-21

1813 Optimizing transcriptome-based synthetic lethality predictions to improve precision oncology in early-stage breast cancer: BC-SELECT

Kim, Y.; Nagy, M.; Pollard, B.; Rajagopal, P. S.

10.1101/2024.08.15.608073 — bioinformatics — Posted on 2024-08-21

1814 Learning and embodied decisions in active inference

Priorelli, M.; Stoianov, I. P.; Pezzulo, G.

10.1101/2024.08.18.608439 — neuroscience — Posted on 2024-08-21

1815 Optimization of TMS target engagement: novel evidence based on combined TMS-EEG and dMRI tractography of brain circuitry

Lioumis, P.; Roine, T.; Grano, I.; Aydogan, D. B.; Ukharova, E.; Souza, V. H.; Kicic, D.; Ilmoniemi, R.; Makris, N.

10.1101/2024.08.19.607213 — neuroscience — Posted on 2024-08-21

1816 Neither fifty percent slow-wave sleep suppression nor fifty percent rapid eye movement sleep suppression does impair memory consolidation

Ukraintseva, Y. V.; Saltykov, K. A.; Tkachenko, O. N.

10.1101/2024.08.19.607534 — neuroscience — Posted on 2024-08-21

1817 GPT-4V shows human-like social perceptual capabilities at phenomenological and neural levels

Santavirta, S.; Wu, Y.; Nummenmaa, L.

10.1101/2024.08.20.608741 — neuroscience — Posted on 2024-08-21

1818 Large scale comparative wheat phosphoproteome profiling pinpoints temperature-associated molecular signatures

Fonseca de Lima, C. F.; Zhu, T.; Van den Broeck, L.; Van De Cotte, B.; Locke, A. M.; Sozzani, R.; De Smet, I.

10.1101/2024.08.20.608123 — plant biology — Posted on 2024-08-21

1819 Natural variation in physical responses to waterlogging across climate-diverse pennycress accessions

Combs-Giroir, R.; Lagergren, J.; Jacobson, D. A.; Gschwend, A. R.

10.1101/2024.08.20.608872 — plant biology — Posted on 2024-08-21

1820 Endophytic pyrroloquinoline quinone enhances banana growth and immunity against Fusarium wilt for plant-microbe mutualisms

Hung, S.-H. W.; Yu, M.-Y.; Liu, C.-H.; Huang, T.-C.; Peng, J.-H.; Jang, N.-Y.; Kuo, C.-H.; Ho, Y.-N.; Chiang, E.-P. I.; Hwang, H.-H.; Huang, C.-C.

10.1101/2024.08.20.608638 — plant biology — Posted on 2024-08-21

1821 Mutant fate in spatially structured populations on graphs: connecting models to experiments

Abbara, A.; Pagani, L.; Garcia-Pareja, C.; Bitbol, A.-F.

10.1101/2024.02.06.579097 — biophysics — Posted on 2024-08-21

1822 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family

Merello, G.; Olivares-Costa, M.; Basile, L.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.

10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-08-21

1823 Evolution of resistance and disease tolerance mechanisms to oral bacterial infection in D. melanogaster

Paulo, T. F.; Akyaw, P. A.; Paixao, T.; Sucena, E.

10.1101/2023.08.23.554397 — evolutionary biology — Posted on 2024-08-21

1824 Solution to what? Global assessment of nature-based solutions, urban challenges, and outcomes

Li, M.; Remme, R. P.; van Bodegom, P. M.; van Oudenhoven, A. P. E.

10.1101/2023.12.07.570577 — ecology — Posted on 2024-08-21

1825 Multi-layered dosage compensation of the avian Z chromosome

Papanicolaou, N.; Lentini, A.; Wettersten, S.; Hagemann-Jensen, M.; Kruger, A.; Zhang, J.; Coucoravas, C.; Petrosian, I.; Xin, X.; Ceyhan, I.; Rorbach, J.; Wright, D.; Reinius, B.

10.1101/2024.08.20.608780 — molecular biology — Posted on 2024-08-21

1826 A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin

Skribbe, M.; Soneson, C.; Stadler, M. B.; Schwaiger, M.; Suma Sreechakram, V. N.; Iesmantavicius, V.; Hess, D.; Pandini Figueiredo Moreno, E.; Braun, S.; Seebacher, J.; Smallwood, S. A.; Buhler, M.

10.1101/2024.08.20.607873 — molecular biology — Posted on 2024-08-21

1827 Embryo-restricted responses to maternal IL-17A promote neurodevelopmental disorders in mouse offspring

Andruszewski, D.; Uhlfelder, D. C.; Desiato, G.; Regen, T.; Blanfeld, M.; Schelmbauer, C.; Scherer, L.; Radyushkin, K.; Pozzi, D.; Waisman, A.; Mufazalov, I. A.

10.1101/2023.12.25.573296 — neuroscience — Posted on 2024-08-21

1828 Identification of phenotypic and transcriptomic signatures underpinning maize crown root systems

Callwood, J. B.; Townsend, E. G.; Malik, S.; Draves, M. A.; Khor, J.; Marshall, J. P.; Sweers, H.; Cowling, C. L.; Walley, J. W.; Kelley, D. R.

10.1101/2024.08.20.608626 — plant biology — Posted on 2024-08-21

1829 Ferroptosis susceptibility of melanoma cells: dependence on cell-type, acquired drug resistance, and medium composition

Preis, J. R.; Rolvering, C.; Kirchmeyer, M.; Halilovic, D.; Wroblewska, J. P.; Tolle, F.; Behrmann, I.; Haan, C.

10.1101/2024.08.12.607529 — cancer biology — Posted on 2024-08-21

1830 Conservation of the cooling agent binding pocket within the TRPM subfamily

Huffer, K.; Denley, M. C. S.; Oskoui, E. V.; Swartz, K. J.

10.1101/2024.05.20.595003 — biophysics — Posted on 2024-08-21

1831 BootCellNet, a resampling-based procedure, promotes unsupervised identification of cell populations via robust inference of gene regulatory networks.

Kumagai, Y.

10.1101/2024.02.06.579236 — bioinformatics — Posted on 2024-08-21

1832 Three-dimensional Label-Free Measurements of Adipocyte Differentiation and Lipid Droplet Dynamics

Jeong, E. Y.; Kim, H.-J.; Lee, S.; Park, Y.; Kim, Y. M.

10.1101/2024.01.06.574492 — biochemistry — Posted on 2024-08-21

1833 Deep Learning and GBLUP Integration: An Approach that Identifies Nonlinear Genetic Relationships Between Traits

Shokor, F.; Croiseau, P.; Gangloff, H.; Saintilan, R.; Tribout, T.; Mary-Huard, T.; C.D Cuyabano, B.

10.1101/2024.03.23.585208 — genomics — Posted on 2024-08-21

1834 A step in the deep evolution of Alvinellidae (Annelida: Polychaeta): a phylogenomic comparative approach based on transcriptomes

Brun, P.-G.; Hourdez, S.; Ballenghien, M.; Zhou, Y.; Mary, J.; Jollivet, D.

10.1101/2023.07.24.550320 — evolutionary biology — Posted on 2024-08-21

1835 Boosting Proteasome Activity: A Novel Mechanism of NMDAR Blockers Against Neurodegeneration

Sahin, F.; Gunel, A.; Atasoy, B. T.; Guler, U.; Salih, B.; Kuzu, I.; Taspinar, M.; Cinar, O.; Kahveci, S.

10.1101/2024.08.20.608787 — neuroscience — Posted on 2024-08-21

1836 Beta Waves in Action: Context-Dependent Modulations of Subthalamo-Cortical Synchronization during Rapid Reversals of Movement Direction

Winkler, L.; Butz, M.; Sharma, A.; Vesper, J.; Schnitzler, A.; Fisher, P.; Hirschmann, J.

10.1101/2024.08.19.608624 — neuroscience — Posted on 2024-08-21

1837 Transcriptional and epigenetic response of rapeseed (Brassica napus L.) to PEG-triggered osmotic stress

Prasad, M.; Shetty, P.; Pal, A.; Kant, K.; Nagy, I.; Shivaprasad, P. V.; Szabados, L.; Rigo, G.; Zsigmond, L.

10.1101/2024.08.19.608641 — plant biology — Posted on 2024-08-21

1838 Transcriptomic profiling of gill biopsies to define predictive markers for seawater survival in farmed Atlantic salmon

Gronvold, L.; Dalum, M. J.; Striberny, A.; Manousi, D.; Ytrestoyl, T.; Morkore, T.; Boison, S.; Gjerde, B.; Jorgensen, E.; Sandve, S. R.; Hazlerigg, D.

10.1101/2024.08.20.608748 — genomics — Posted on 2024-08-21

1839 Impaired DNA damage response and inflammatory signalling underpins hematopoietic stem cell defects in Gata2 haploinsufficiency

Abdelfattah, A.; Habib, A.; Thomas, L.-a.; Menendez-Gonzalez, J. B.; Almotiri, A.; Alqahtani, H.; Lawson, H.; Taha, S.; Steadman, M.; Athalye, R.; Gibbs, A.; Alzahrani, H.; Cato, A.; Giles, P.; Tonks, A.; Boyd, A. S.; Kranc, K. R.; Rodrigues, N.

10.1101/2024.08.20.608056 — cancer biology — Posted on 2024-08-21

1840 CLEAR-IT: Contrastive Learning to Capture the Immune Composition of Tumor Microenvironments

Spengler, D.; Korovin, S.; Prakash, K.; Bankhead, P.; Debets, R.; Smith, C.; Balcioglu, H. E.

10.1101/2024.08.20.608738 — bioinformatics — Posted on 2024-08-21

1841 Endoplasmic reticulum patterns insect cuticle nanostructure

Inagaki, S.; Wada, H.; Itabashi, T.; Itakura, Y.; Nakagawa, R.; Chen, L.; Murata, K.; Iwane, A. H.; Hayashi, S.

10.1101/2024.08.20.608717 — developmental biology — Posted on 2024-08-21

1842 Archaic introgression and the distribution of shared variation under stabilizing selection

Ragsdale, A. P.

10.1101/2024.08.20.608876 — evolutionary biology — Posted on 2024-08-20

1843 Distinct roles of prefrontal cortex neurons in set shifting

Nigro, M.; Tortorelli, L.; Yang, H.

10.1101/2024.08.20.608808 — neuroscience — Posted on 2024-08-20

1844 Dev-Atlas: A reference atlas of functional brain networks for typically developing adolescents

Doucet, G.; Goldsmith, C.; Myers, K.; Rice, D.; Ende, G.; Pavelka, D. J.; Joliot, M.; Calhoun, V.; Wilson, T. W.; Uddin, L. Q.

10.1101/2024.08.20.608658 — neuroscience — Posted on 2024-08-20

1845 Nicotine engages a VTA-NAc feedback loop to inhibit amygdala-projecting dopamine neurons and induce anxiety.

Marti, F.; Faure, P.; Le Borgne, T.; Nguyen, C.; Vicq, E.; Jehl, J.; Solie, C.; Guyon, N.; Daussy, L.; Gulmez, A.; Reynolds, L.; Mondoloni, S.; Tolu, S.; Pons, S.; Maskos, U.; Valjent, E.; Mourot, A.

10.1101/2024.08.20.607920 — neuroscience — Posted on 2024-08-20

1846 Influence of social and semantic contexts in processing speech in noise

Abassi, E.; Zatorre, R.

10.1101/2024.01.10.575068 — neuroscience — Posted on 2024-08-21

1847 Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

Buhmann, Z.; Robinson, A. K.; Mattingley, J. B.; Rideaux, R.

10.1101/2024.02.15.580589 — neuroscience — Posted on 2024-08-21

1848 Re-evaluating the relationship between female social bonds and infant survival in wild baboons

Creighton, M. J. A.; Lerch, B. A.; Lange, E. C.; Silk, J. B.; Tung, J.; Archie, E. A.; Alberts, S. C.

10.1101/2024.08.20.608854 — animal behavior and cognition — Posted on 2024-08-20

1849 Evolutionary and Functional Analysis of Monoamine Oxidase C (MAO C): A Novel Member of the MAO Gene Family

Merello, G.; Olivares-Costa, M.; Basile, M.; Pastor, T. P.; Mendoza-Soto, P.; Padilla-Santiago, L.; Mardones, G.; Binda, C.; Opazo, J. C.

10.1101/2024.08.20.608864 — evolutionary biology — Posted on 2024-08-20

1850 p53 mediated regulation of LINE1 retrotransposon derived R-loops

Paul, P.; Kumar, A.; De, A. K.; Parida, A. S.; Bhadke, G. V.; Khatua, S.; Pattanayak, F.; Tiwari, B.

10.1101/2024.04.12.589154 — cancer biology — Posted on 2024-08-20

1851 Metadichol induced Toll Like Receptors expression in Cancer Cell Lines

Raghavan, P. R.

10.1101/2024.08.18.608483 — cancer biology — Posted on 2024-08-20

1852 Structure of the T=13 capsid of infectious pancreatic necrosis virus (IPNV) - a salmonid birnavirus

Munke, A.; Ahmed Abdelrahim Gamil, A.; Mikalsen, A. B.; Wang, H.; Evensen, O.; Okamoto, K.

10.1101/2024.08.20.608766 — biophysics — Posted on 2024-08-20

1853 From resting state to inactivation: the dynamic journey of the inactivation peptide in Shaker Kv channels

Pandey, R.; Kalstrup, T.; Blunck, R.

10.1101/2024.07.10.602816 — biophysics — Posted on 2024-08-20

1854 Silver chimaera genome assembly and identification of the holocephalan sex chromosome sequence

Teramura, A.; Kadota, M.; Hirase, S.; Kuraku, S.; Kikuchi, K.

10.1101/2024.08.20.608884 — genomics — Posted on 2024-08-20

1855 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-20

1856 A unified theoretical framework for invasion in host-symbiont communities

Martignoni, M. M.; Garnier, J. M.; Tyson, R. C.; Harris, K. D.; Kolodny, O.

10.1101/2024.01.18.576278 — ecology — Posted on 2024-08-20

1857 PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits

Xiong, W.; Qin, M.; Zhong, H.

10.1101/2023.09.05.556437 — cell biology — Posted on 2024-08-20

1858 Multi-layered dosage compensation of the avian Z chromosome

Papanicolaou, N.; Lentini, A.; Wettersten, S.; Hagemann-Jensen, M.; Kruger, A.; Zhang, J.; Coucoravas, C.; Petrosian, I.; Xin, X.; Ceyhan, I.; Rorbach, J.; Wright, D.; Reinius, B.

10.1101/2024.08.20.608780 — molecular biology — Posted on 2024-08-20

1859 Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesity

Alharithi, Y. J.; Phillips, E. A.; Wilson, T. D.; Couvillion, S. P.; Nicora, C. D.; Darakjian, P.; Rakshe, S.; Fei, S. S.; Counts, B.; Zimmers, T.; Metz, T. O.; Searles, R.; Kumar, S.; Maloyan, A.

10.1101/2024.08.20.608809 — molecular biology — Posted on 2024-08-20

1860 Herpes Simplex Virus 1 Envelope Glycoprotein C Shields Glycoprotein D to Protect Virions from Entry-Blocking Antibodies

Hull, M.; Pritchard, S. M.; Nicola, A. V.

10.1101/2024.08.20.608756 — microbiology — Posted on 2024-08-20

1861 Live-tracking of replisomes reveals nutrient-dependent regulation of replication elongation rates in Caulobacter crescentus

Adhikashreni, I. S.; Joseph, A. M.; Phadke, S.; Badrinarayanan, A.

10.1101/2024.08.20.608768 — microbiology — Posted on 2024-08-20

1862 Multivalent administration of dengue E dimers on liposomes elicits type-specific neutralizing responses without immune interference

Phan, T. T. N.; Hvasta, M. G.; Thiono, D. J.; Shah, R. P.; Ajo, G. P.; Huang, W.-c.; Lovell, J.; Tian, S.; de Silva, A. M.; Kuhlman, B.

10.1101/2024.08.20.608851 — microbiology — Posted on 2024-08-20

1863 Temperate phage-antibiotic synergy is widespread, but varies by phage, host, and antibiotic pairing

Fatima, R.; Hynes, A. P.

10.1101/2024.08.20.608816 — microbiology — Posted on 2024-08-20

1864 PRRSV-2 variant classification: a dynamic nomenclature for enhanced monitoring and surveillance

VanderWaal, K.; Pamornchainavakul, N.; Kikuti, M.; Zhang, J.; Zeller, M.; Trevisan, G.; Rossow, S.; Schwartz, M.; Linhares, D. C. L.; Holtkamp, D. J.; da Silva, J. P. H.; Corzo, C. A.; Baker, J. P.; Anderson, T. K.; Makau, D. N.; Paploski, I. A. D.

10.1101/2024.08.20.608841 — microbiology — Posted on 2024-08-20

1865 Re-programming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation

Rios, I.; Herrero, C.; Torres Torresano, M.; Lopez-Navarro, B.; Schiaffino, M. T.; Diaz Crespo, F.; Nieto-Valle, A.; Samaniego, R.; Sierra-Palomares, Y.; Oliver, E.; Revuelta, F.; Garcia-Lujan, R.; Sanchez-Mateos, P.; Delgado, R.; Puig-Kroger, A.; Corbi, A. L.

10.1101/2024.08.20.608749 — immunology — Posted on 2024-08-20

1866 Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy

Mubarak, H. F.; Tan, W.; Hoffmann, A. D.; Sun, Y.; Wei, J.; El-Shennawy, L.; Squires, J. R.; Dashzeveg, N. K.; Simonton, B.; Jia, Y.; Iyer, R.; Xu, Y.; Nicolaescu, V.; Elli, D.; Randall, G. C.; Schipma, M. J.; Swaminathan, S.; Ison, M. G.; Liu, H.; Fang, D.; Shen, Y.

10.1101/2024.03.01.582176 — immunology — Posted on 2024-08-20

1867 A neural basis for mutant ATAXIN-1 induced respiratory dysfunction in mouse models of Spinocerebellar ataxia type 1

Soles, A.; Grittner, J.; Douglas, K.; Yang, P.; Barnett, R.; Chau, C.; Cosiquien, R.; Duvick, L.; Rainwater, O.; Serres, S.; Orr, H.; Dougherty, B.; Cvetanovic, M.

10.1101/2024.08.20.608114 — neuroscience — Posted on 2024-08-20

1868 Molecular Insights into Neuronal Dysfunction in GM2 Gangliosidoses

Nicholson, A. S.; Priestman, D. A.; Antrobus, R.; Williamson, J. C.; Bush, R.; Barrow, H. G.; Smith, E.; Dobrenis, K.; Bright, N. A.; Platt, F. M.; Deane, J. E.

10.1101/2024.08.20.608810 — neuroscience — Posted on 2024-08-20

1869 Decoding reveals the neural representation of perceived and imagined musical sounds

Quiroga-Martinez, D. R.; Fernandez-Rubio, G.; Bonetti, L.; Achyutuni, K. G.; Tzovara, A.; Knight, R. T.; Vuust, P.

10.1101/2023.08.15.553456 — neuroscience — Posted on 2024-08-20

1870 Cycling DOF Factor mediated seasonal regulation of sexual reproduction and cold response is not conserved in Physcomitrium patens

Freidinger, A. G.; Woodward, L. A.; Bui, J. T.; Doty, G.; Ruiz, S.; Conant, E.; Hicks, K. A.

10.1101/2024.08.20.608156 — plant biology — Posted on 2024-08-20

1871 Distinct Roles for the Thioredoxin and Glutathione Antioxidant Systems in Nrf2-Mediated Lung Tumor Initiation and Progression

Sherwood, A. M.; DeBlasi, J. M.; Caldwell, S.; DeNicola, G. M.

10.1101/2024.08.20.608800 — cancer biology — Posted on 2024-08-20

1872 Motor-driven microtubule diffusion in a photobleached dynamical coordinate system

Hirokawa, S.; Lee, H. J.; Banks, R. A.; Duarte, A. I.; Najma, B.; Thomson, M.; Phillips, R.

10.1101/2024.08.20.608861 — biophysics — Posted on 2024-08-20

1873 High throughput mutational scanning of a protein via alchemistry on a high-performance computing resource

Guclu, T. F.; Tayhan, B.; Cetin, E.; Atilgan, A. R.; ATILGAN, C.

10.1101/2024.08.20.608765 — biophysics — Posted on 2024-08-20

1874 Enhanced metagenomics-enabled transmission inference with TRACS

Tonkin-Hill, G.; Shao, Y.; Zarebski, A. E.; Mallawaarachchi, S.; Xie, O.; Maklin, T.; Thorpe, H. A.; Davies, M. R.; Bentley, S. D.; Lawley, T. D.; Corander, J.

10.1101/2024.08.19.608527 — bioinformatics — Posted on 2024-08-20

1875 Severe deviation in protein fold prediction by advanced AI: a case study

Lopez-Sagaseta, J.; Urdiciain, A.

10.1101/2024.08.20.608820 — biochemistry — Posted on 2024-08-20

1876 The molecular mechanism of temperature-dependent phase separation of Heat shock factor 1

Ren, Q.; Li, L.; Li, J.; Shi, C.; Sun, Y.; Yao, X.; Hou, Z.; Xiang, S.

10.1101/2024.08.20.608825 — biochemistry — Posted on 2024-08-20

1877 Interrelationship of substrate crystallinity, enzyme binding strength, and cellulase activity

Avelar Molina, G.; Schaller, K.; Kari, J.; Schiano-di-Cola, C.; H. J. Peters, G.; Borch, K.; Westh, P.

10.1101/2024.08.20.607150 — biochemistry — Posted on 2024-08-20

1878 Lipid- and protein-directed photosensitizer proximity labeling captures the cholesterol interactome

Becker, A. p.; Biletch, E.; Kennelly, J. P.; Julio, A. R.; Villanueva, M.; Nagari, R.; Turner, D. W.; Burton, N. R.; Fukuta, T.; Cui, L.; Xiao, X.; Hong, S.-G.; Mack, J. J.; Tontonoz, P.; Backus, K.

10.1101/2024.08.20.608660 — biochemistry — Posted on 2024-08-20

1879 Quantifying microbial fitness in high-throughput experiments

Fink, J. W.; Manhart, M.

10.1101/2024.08.20.608874 — evolutionary biology — Posted on 2024-08-20

1880 Stabilizing selection generates selection against introgressed DNA

Veller, C.; Simons, Y.

10.1101/2024.08.20.608860 — evolutionary biology — Posted on 2024-08-20

1881 ERH regulates type II interferon immune signaling through post-transcriptional regulation of JAK2 mRNA

Soderholm, A.; Vunjak, M.; DeAlmeida, M.; Popitsch, N.; Podvalnaya, N.; Araguas-Rodriguez, P.; Scinicariello, S.; Nischwitz, E.; Butter, F.; Ketting, R.; Ameres, S. L.; Mueller-McNicoll, M.; Zuber, J.; Versteeg, G. A.

10.1101/2024.08.20.607899 — cell biology — Posted on 2024-08-20

1882 Evidencing the role of a conserved polar signaling channel in the activation mechanism of the u-opioid receptor

Sarkar, A.; Dvoracsko, S.; Lipinszki, Z.; Mitra, A.; Harmati, M.; Buzas, K.; Borics, A.

10.1101/2024.08.20.608751 — molecular biology — Posted on 2024-08-20

1883 Detection of protein-protein interactions by bio-orthogonal fluorogenic proximity probes

Torell, A.; Larsson, N. A.; Phillipson, S. K.; Odell, L. R.; Furth, D.

10.1101/2024.08.20.608485 — molecular biology — Posted on 2024-08-20

1884 The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity

Tran, C. J.; Zubair-Nizami, Z. B.; Langohr, I. M.; Welch, M. D.

10.1101/2024.08.20.608656 — microbiology — Posted on 2024-08-20

1885 Aspergillus fumigatus SidF is a dual substrate acyltransferase involved in biosynthesis of both fusarinine- and ferrichrome-type siderophores

Caballero, P.; Yap, A.; Oberegger, S.; Happacher, I.; Poonsiri, T.; Benini, S.; Haas, H.

10.1101/2024.08.20.608788 — microbiology — Posted on 2024-08-20

1886 Description of Bacterial RNA Transcripts Detected in Mycobacterium tuberculosis Infected Cells from Peripheral Human Granulomas using Single Cell RNA Sequencing

Moos, P. J.; Carey, A. F.; Joseph, J.; Kialo, S.; Norrie, J.; Moyarelce, J. M.; Amof, A.; Nogua, H.; Lim, A. L.; Barrows, L. R.

10.1101/2024.08.20.608852 — microbiology — Posted on 2024-08-20

1887 A modular model of immune response as a computational platform to investigate a pathogenesis of infection disease

Miroshnichenko, M.; Kolpakov, F. A.; Akberdin, I. R.

10.1101/2024.08.19.608570 — systems biology — Posted on 2024-08-20

1888 Genomic loci for sclerotinia stem rot resistance and chlorophyll stability in Brassica napus: integrating GWAS with microbiome insights

Chawade, A.; Thuraga, V.; Sepp, S. S.; Ghosh, S.; Ghadamgahi, F.; Odilbekov, F.; Muthusamy, S.; Vetukuri, R. R.; Abreha, K. B.

10.1101/2024.08.20.608782 — plant biology — Posted on 2024-08-20

1889 Gut Commensal Bacteria-Derived Methionine is Required for Host Reproduction by Modulating RNA m6A Methylation of the Insulin Receptor

Zhang, Q.; Deng, Z.; Li, X.; Qiao, J.; Li, Z.; Liu, P.; Handler, A. M.; Lemaitre, B.; Zheng, W.; Zhang, H.

10.1101/2024.08.20.608724 — microbiology — Posted on 2024-08-20

1890 CLEAR-IT: Contrastive Learning Enabled Accurate Registration of Immune and Tumor cells from multiplexed images with limited labels in a platform-independent manner

Spengler, D.; Korovin, S.; Prakash, K.; Bankhead, P.; Debets, R.; Smith, C.; Balcioglu, H. E.

10.1101/2024.08.20.608738 — bioinformatics — Posted on 2024-08-20

1891 Protein Language Models in Directed Evolution

Maguire, R.; Bloznelyte, K.; Adepoju, F.; Armean-Jones, M.; Dewan, S.; Gupta, A.; Jones, F. P.; Lalli, P.; Schooneveld, A.; Thompson, S.; Ebrahimi, E.; Fozzard, S.; Berman, D.; Rossoni, L.; Addison, W.; Taylor, I.

10.1101/2024.08.20.608752 — bioinformatics — Posted on 2024-08-20

1892 Amber Codon Mutational Scanning and Bioorthogonal PEGylation for Mapping Antibody Binding Sites on Human Arginase-1

Fernandez de Santaella, J.; Koch, N. G.; Widmer, L.; Nash, M.

10.1101/2024.08.20.608740 — bioengineering — Posted on 2024-08-20

1893 A comprehensive Schizosaccharomyces pombe atlas of physical transcription factor interactions with proteins and chromatin

Skribbe, M.; Soneson, C.; Stadler, M. B.; Schwaiger, M.; Suma Sreechakram, V. N.; Iesmantavicius, V.; Hess, D.; Pandini Figueiredo Moreno, E.; Braun, S.; Seebacher, J.; Smallwood, S. A.; Buhler, M.

10.1101/2024.08.20.607873 — molecular biology — Posted on 2024-08-20

1894 Abundant and active community members respond to the diel cycle in hot spring phototrophic mats

Shelton, A. N.; Yu, F. B.; Grossman, A. R.; Bhaya, D.

10.1101/2024.08.19.608644 — microbiology — Posted on 2024-08-20

1895 Epigenetic control of tetrapyrrole biosynthesis by m4C DNA methylation in a cyanobacterium

Schmidt, N.; Stappert, N.; Nimura-Matsune, K.; Watanabe, S.; Sobotka, R.; Hagemann, M.; Hess, W. R.

10.1101/2024.08.20.608618 — microbiology — Posted on 2024-08-20

1896 Spontaneous Dimerization and Distinct Packing Modes of Transmembrane Domains in Receptor Tyrosine Kinases

Levintov, L.; Gorai, B.; Vashisth, H.

10.1101/2024.05.09.593448 — biophysics — Posted on 2024-08-20

1897 On the identification of differentially-active transcription factors from ATAC-seq data

Gerbaldo, F. E.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.

10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-08-20

1898 Integrating tDNA Epigenomics and Expression with Codon Usage Unravel an Intricate Connection with Protein Expression Dynamics in Trypanosoma cruzi

Silva, H. G. d. S.; Kimura, S.; de Lima, P. L. C. P.; Pires, D. d. S.; Waldor, M. K.; da Cunha, J. P.

10.1101/2024.07.04.602108 — cell biology — Posted on 2024-08-20

1899 Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

Bi, Z.; Chen, Y.-X.; Young, I. D.; Su, H.; Chen, Y.; Hong, J.; Fraser, J. S.; Javid, B.

10.1101/2021.03.02.433644 — molecular biology — Posted on 2024-08-20

1900 Borrelia burgdorferi Secretes c-di-AMP as an Extracellular Pathogen-Associated Molecular Pattern to Elicit Type I Interferon Responses in Mammalian Hosts

Priya, R.; Ye, M.; Raghunanadanan, S.; Liu, Q.; Li, W.; Yu, Q.; Lou, Y.; Sintim, H. O.; Yang, X. F.

10.1101/2024.08.13.607721 — immunology — Posted on 2024-08-20

1901 Sleep need driven oscillation of glutamatergic synaptic phenotype

Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.

10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-08-20

1902 Neural Prioritisation of Past Solutions Supports Generalisation

Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.

10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-08-20

1903 Duration of Morning Hyperinsulinemia Determines Hepatic Glucose Uptake and Glycogen Storage Later in the Day

Waterman, H. L.; Moore, M. C.; Smith, M.; Farmer, B.; Scott, M.; Edgerton, D. S.; Cherrington, A. D.

10.1101/2024.05.10.593551 — physiology — Posted on 2024-08-20

1904 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-20

1905 Multicellular, fluid flow-inclusive hepatic in vitro models using NANOSTACKS™: a human-relevant model for drug response prediction

Talari, A.; Sbordoni, R.; Hoti, V.; Patel, I. I.; Martin, F. L.; Raza, A.; Llabjani, V.

10.1101/2024.08.12.607396 — cell biology — Posted on 2024-08-20

1906 A Highly-Efficient, Scalable Pipeline for Fixed Feature Extraction from Large-Scale High-Content Imaging Screens

Comolet, G.; Bose, N.; Winchell, J. M.; Duren-Lubancki, a.; Rusielewicz, T.; Horn, g.; Goldberg, j.; Paull, D.; Migliori, B.

10.1101/2023.07.06.547985 — cell biology — Posted on 2024-08-20

1907 Topical ABT-1 263 treatment reduces aged skin senescence and improves subsequent wound healing

Shvedova, M.; Thanapaul, R. J. R. S.; Ha, J.; Dhillon, J.; Shin, G. H.; Crouch, J.; Gower, A. C.; Gritli, S.; Roh, D. S.

10.1101/2024.08.19.608670 — cell biology — Posted on 2024-08-20

1908 Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease

Jamadar, A.; Ward, C. J.; Remadevi, V.; Varghese, M. M.; Pabla, N. S.; Gumz, M. L.; Rao, R.

10.1101/2024.08.05.606676 — molecular biology — Posted on 2024-08-20

1909 Dysregulation of cholesterol and bile acid homeostasis across the gut-liver axis following Cryptosporidium intestinal infection

Wang, S.; Gong, A.-Y.; Barker, E.; Williams, D. L.; Forsyth, C.; Yu, L.; Chen, X.-M.

10.1101/2024.08.01.606233 — microbiology — Posted on 2024-08-20

1910 Automated multimodal imaging of Caenorhabditis elegans behavior in multi-well plates

Ji, H.; Chen, D.; Fang-Yen, C.

10.1101/2024.02.09.579675 — neuroscience — Posted on 2024-08-20

1911 Comparison between EEG and MEG of static and dynamic resting-state networks

Cho, S.; van Es, M. W. J.; Woolrich, M. W.; Gohil, C.

10.1101/2024.04.29.591774 — neuroscience — Posted on 2024-08-20

1912 Repetition effects reveal the sub-sequence representation of actions

Shahbazi, M.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/2024.08.07.607016 — neuroscience — Posted on 2024-08-20

1913 Sniffing can be initiated by the actions of dopamine on ventral striatum neurons

Johnson, N. L.; Cotelo-Larrea, A.; Stetzik, L. A.; Akkaya, U. M.; Zhang, Z.; Gadziola, M. A.; Varga, A. G.; Ma, M.; Wesson, D. W.

10.1101/2024.02.19.581052 — neuroscience — Posted on 2024-08-20

1914 Designing host-associated microbiomes using the consumer/resource model

Plata, G. D.; Srinivasan, K.; Krishnamurthy, M.; Herron, L.; Dixit, P.

10.1101/2023.04.28.538625 — systems biology — Posted on 2024-08-20

1915 Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice.

Roberts, E.; Bhurke, A. V.; Ganeshkumar, S.; Gunewardena, S.; Arora, R.; Chennathukuzhi, V. M.

10.1101/2024.08.06.605120 — physiology — Posted on 2024-08-20

1916 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models

Zhang, Y.; Savvidou, M.; Liaudanskaya, V.; Ramanathan, V.; Bui, T.; Matthew, L.; Sze, A.; Ugwu, U. O.; Yuhang, F.; Matthew, D. E.; Chen, X.; Nasritdinova, S.; Dey, A.; Miller, E. L.; Kaplan, D. L.; Georgakoudi, I.

10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-20

1917 Engineering Planar Gram-Negative Outer Membrane Mimics Using Bacterial Outer Membrane Vesicles

Singh, A. N.; Wu, M.; Ye, T. T.; Brown, A. C.; Wittenberg, N. J.

10.1101/2023.12.11.570829 — bioengineering — Posted on 2024-08-20

1918 Harmonization of the fastest and densest responses embodies the humanlike reaction time of mice

Kim, C. H.

10.1101/2024.04.17.590007 — animal behavior and cognition — Posted on 2024-08-20

1919 Pollen foraging mediates exposure to dichotomous stressor syndromes in honey bees

Wizenberg, S. B.; French, S. K.; Newburn, L. R.; Pepinelli, M.; Conflitti, I. M.; Moubony, M.; Ritchie, C.; Jamieson, A.; Richardson, R. T.; Travas, A.; Imrit, M. A.; Chihata, M.; Higo, H.; Common, J.; Walsh, E. M.; Bixby, M.; Guarna, M. M.; Pernal, S. F.; Hoover, S. E.; Currie, R. W.; Giovenazzo, P.; Guzman-Novoa, E.; Borges, D.; Foster, L. J.; Zayed, A.

10.1101/2024.08.20.608746 — ecology — Posted on 2024-08-20

1920 Mitochondrial calcium modulates odor-mediated behavioral plasticity in C. elegans

Lee, H. K.; Joo, D.-K.; Park, K.-S.; Yoon, K.-h.

10.1101/2023.08.29.555059 — neuroscience — Posted on 2024-08-20

1921 An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression

Subramanian, R.; Bauman, A.; Carpenter, O.; Cho, C.; Coste, G.; Dam, A.; Drake, K.; Ehnstrom, S.; Fitzgerald, N.; Jenkins, A.; Koolpe, H.; Liu, R.; Paserman, T.; Petersen, D.; Chavez, D. S.; Rozental, S.; Thompson, H.; Tsukuda, T.; Zweig, S.; Gall, M.; Zupan, B.; Bergstrom, H.

10.1101/2024.08.18.608308 — neuroscience — Posted on 2024-08-20

1922 In silico characterisation of PAL homologs and metabolomic profiling of shade response indicates potential presence of PTALs and Tyr as a probable precursor of lignin biosynthesis in conifers

Ranade, S. S.; Garcia-Gil, M. R.

10.1101/2024.08.20.608774 — plant biology — Posted on 2024-08-20

1923 WITHDRAWN: Caveolar Compartmentalization is Required for Stable Rhythmicity of Sinus Nodal Cells and is Disrupted in Heart Failure

Lang, D.; Ni, H.; Medvedev, R.; Liu, F. V.; Tyan, L.; Turner, D.; Warden, A.; Morotti, S.; Schrauth, T.; Chanda, B.; Kamp, T. J.; Robertson, G.; Grandi, E.; Glukhov, A. V.

10.1101/2024.04.14.589457 — physiology — Posted on 2024-08-20

1924 Approaches to dimensionality reduction for ultra-high dimensional models

Kotlarz, K.; Slomian, D.; Szyda, J.

10.1101/2024.08.20.608783 — bioinformatics — Posted on 2024-08-20

1925 The winner's curse under dependence: repairing empirical Bayes using convoluted densities

Hawinkel, S.; Thas, O.; Maere, S.

10.1101/2023.09.22.558978 — bioinformatics — Posted on 2024-08-20

1926 A Real-time Multi-Subject Three Dimensional Pose Tracking System for Analyzing Social Behaviors of Non-human Primates

Cheng, C.; Huang, Z.; Zhang, R.; Huang, G.; Wang, H.; Tang, L.; Wang, X.

10.1101/2024.02.27.582429 — animal behavior and cognition — Posted on 2024-08-20

1927 Understanding indirect assortative mating and its intergenerational consequences

Sunde, H. F.; Eilertsen, E. M.; Torvik, F. A.

10.1101/2024.06.21.600029 — genetics — Posted on 2024-08-20

1928 The effects of selfing on lineage diversification across multiple genera

Xu, K.

10.1101/2024.08.20.608795 — evolutionary biology — Posted on 2024-08-20

1929 Grains, trade and war in the multimodal transmission of Rice yellow mottle virus: an historical and phylogeographical retrospective

Ndikumana, I.; Onaga, G.; Pinel-Galzi, A.; Rocu, P.; Hubert, J.; Were, H. K.; Adego, A. K.; Were, M. N.; Poulicard, N.; Hebrard, M.; Dellicour, S.; Lemey, P.; Gilbert, E.; Dugue, M.-J.; Chevenet, F.; Bastide, P.; Guindon, S.; Fargette, D.; Hebrard, E.

10.1101/2024.08.20.608750 — evolutionary biology — Posted on 2024-08-20

1930 Tree nursery environments and their effect on early trait variation

Perry, A.; Beaton, J. K.; Stockan, J. A.; Iason, G. R.; Cottrell, J. E.; Cavers, S.

10.1101/2024.08.20.608769 — ecology — Posted on 2024-08-20

1931 Shaping the structural dynamics of motor learning through cueing during sleep

Stee, W.; Legouhy, A.; Guerreri, M.; Zhang, H.; Peigneux, P.

10.1101/2024.08.16.608370 — neuroscience — Posted on 2024-08-20

1932 Harnessing light heterogeneity to optimise controlled environment agriculture

Claydon, W.; Redmond, E. J.; Vong, G. Y.; Kluczkovski, A.; Thomas, A.; Sutton, P.; Denby, K.; Ezer, D.

10.1101/2024.08.20.608762 — plant biology — Posted on 2024-08-20

1933 Class II Kinesin-12 facilitates cell plate formation by transporting cell plate materials in the phragmoplast

Yamada, M.; Matsuyama, H. J.

10.1101/2024.08.20.608524 — plant biology — Posted on 2024-08-20

1934 Technical Assessment on Proteonano: A Robust Platform for Deep Plasma Proteomics Study

Wang, Y.; Zhang, Y.; Ouyang, X.; Wu, H.

10.1101/2024.08.20.608582 — biochemistry — Posted on 2024-08-20

1935 Single-residue effects on the behavior of a nascent polypeptide chain inside the ribosome exit tunnel

Pardo Avila, F.; Kudva, R.; Levitt, M.; Von Heijne, G.

10.1101/2024.08.20.608737 — biochemistry — Posted on 2024-08-20

1936 Exploring mate choice and male strategies in a polymorphic moth

Selenius, E.; De Pasqual, C.; Hanninen, M.; Kartano, L.; Winters, S.; Mappes, J.

10.1101/2024.08.20.608604 — evolutionary biology — Posted on 2024-08-20

1937 Mechanical control of the insect extracellular matrix nanostructure

Itakura, Y.; Wada, H.; Inagaki, S.; Hayashi, S.

10.1101/2024.08.20.608778 — developmental biology — Posted on 2024-08-20

1938 Epithelial-mesenchymal boundary guides cell shapes and axis elongation in embryonic explants

Barrett, K.; Anand, S.; Thome, V.; Merkel, M.; Lenne, P.-F.

10.1101/2024.08.20.608779 — developmental biology — Posted on 2024-08-20

1939 GDC: An Integrated Resource to Explore the Pathogenesis of Hearing Loss through Genetics and Genomics

Cheng, H.; Wang, X.; Zhong, M.; Geng, J.; Li, W.; Pei, K.; Lu, Y.; Cheng, J.; Bu, F.; Yuan, H.

10.1101/2024.08.19.608726 — genetics — Posted on 2024-08-20

1940 High-throughput affinity measurements of direct interactions between activation domains and co-activators

DelRosso, N.; Suzuki, P.; Griffith, D.; Lotthammer, J.; Novak, B.; Kocalar, S.; Sheth, M.; Holehouse, A.; Bintu, L.; Fordyce, P.

10.1101/2024.08.19.608698 — biophysics — Posted on 2024-08-20

1941 Tesorai Search: Large pretrained model boosts identifications in mass spectrometry proteomics without the need for Percolator.

Burq, M.; Stepec, D.; Restrepo, J.; Zbontar, J.; Urazbakhtin, S.; Crampton, B.; Tiwary, S.; Miao, M.; Cox, J.; Cimermancic, P.

10.1101/2024.08.19.606805 — bioinformatics — Posted on 2024-08-20

1942 DIAMOND2GO: A rapid Gene Ontology assignment and enrichment tool for functional genomics

Golden, C.; Studholme, D. J.; Farrer, R. A.

10.1101/2024.08.19.608700 — bioinformatics — Posted on 2024-08-20

1943 De Novo Genome Assembly and Annotation for the Webbing Clothes Moth (Tineola bisselliella): A Globally Distributed, Economically Important Pest

Alqassar, J. D.; Aichelman, H. E.; Novick, I. A.; Mullen, S. P.

10.1101/2024.08.19.604795 — genomics — Posted on 2024-08-20

1944 The polygenic strategies of Botrytis cinerea for virulence across eight eudicot host species

Caseys, C.; Kliebenstein, D. J.

10.1101/2024.08.19.608699 — genetics — Posted on 2024-08-20

1945 Comprehensive Genomic and Evolutionary Analysis of Biofilm Matrix Clusters and Proteins in the Vibrio Genus

Yang, Y.; Yan, J.; Olson, R.; Jiang, X.

10.1101/2024.08.19.608685 — evolutionary biology — Posted on 2024-08-20

1946 Navigating "tip fog": Embracing uncertainty in tip measurements

Beaulieu, J. M.; O'Meara, B. C.

10.1101/2024.08.19.608647 — evolutionary biology — Posted on 2024-08-20

1947 Enhanced Golden Gate Assembly: Evaluating Overhang Strength for Improved Ligation Efficiency

Strzelecki, P.; Joly, N.; Hebraud, P.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Busi, F.; Grange, W.

10.1101/2022.09.09.507109 — molecular biology — Posted on 2024-08-20

1948 Halofilins as Emerging Bactofilin Families of Archaeal Cell Shape Plasticity Orchestrators

Curtis, Z.; Escudeiro, P.; Mallon, J. L.; Leland, O.; Rados, T.; Dodge, A.; Andre, K.; Kwak, J.; Yun, K.; Isaac, B.; Martinez Pastor, M.; Schmid, A.; Pohlschroder, M.; Alva, V.; Bisson, A.

10.1101/2024.01.22.576759 — microbiology — Posted on 2024-08-20

1949 High-resolution mapping of cell-cycle dynamics during T-cell development and regeneration in vivo

Kunze-Schumacher, H.; Verheyden, N. A.; Grewers, Z.; Meyer-Hermann, M.; Greiff, V.; Robert, P. A.; Krueger, A.

10.1101/2023.06.14.544919 — immunology — Posted on 2024-08-20

1950 Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

Stolz, V.; de Freitas e Silva, R.; Rica, R.; Zhu, C.; Preglej, T.; Hamminger, P.; Hainberger, D.; Alteneder, M.; Müller, L.; Waldherr, M.; Waltenberger, D.; Hladik, A.; Agerer, B.; Schuster, M.; Frey, T.; Krausgruber, T.; Knapp, S.; Campbell, C.; Schmetterer, K.; Trauner, M.; Bergthaler, A.; Bock, C.; Boucheron, N.; Ellmeier, W.

10.1101/2022.03.24.485609 — immunology — Posted on 2024-08-20

1951 Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology

Barnett, D.; Zimmer, T. S.; Booraem, C.; Palaguachi, F.; Meadows, S. M.; Xiao, H.; Chouchani, E. T.; Orr, A. G.; Orr, A. L.

10.1101/2024.08.19.608708 — neuroscience — Posted on 2024-08-20

1952 Bidirectional Optogenetic Modulations of Peripheral Sensory Nerve Activity: Induction vs. Suppression through Channelrhodopsin and Halorhodopsin

Kosugi, A.; Inoue, K.-i.; Takada, M.; Seki, K.

10.1101/2024.08.15.608055 — neuroscience — Posted on 2024-08-20

1953 Both major xanthophyll cycles present in nature can provide Non-Photochemical Quenching in the model diatom Phaeodactylum tricornutum

Giossi, C. E.; Wünsch, M. A.; Dautermann, O.; Schober, A. F.; Buck, J. M.; Kroth, P. G.; Lohr, M.; Lepetit, B.

10.1101/2024.03.19.584964 — plant biology — Posted on 2024-08-20

1954 Early Natural History of Cardiomyopathy and Cardiac Stress Response in Young Dogs with Golden Retriever Muscular Dystrophy

Guo, L.-J.; Nghiem, P. P.; Bettis, A. K.; Soslow, J. H.; Spurney, C.; Kornegay, J. N.

10.1101/2024.08.19.608721 — physiology — Posted on 2024-08-20

1955 Lactobacillus Restructures the Micro/Mycobiome to Combat Glycoprotein-130 Associated Microtubule Remodeling and Right Ventricular Dysfunction in Pulmonary Arterial Hypertension

Prisco, S. Z.; Blake, M.; Kazmirczak, F.; Moon, R.; Vogel, N.; Moutsoglou, D.; Thenappan, T.; Prins, K. W.

10.1101/2024.08.19.608469 — physiology — Posted on 2024-08-20

1956 Validation of a Microfluidic Device Prototype for Cancer Detection and Identification: Circulating Tumor Cells Classification Based on Cell Trajectory Analysis Leveraging Cell-Based Modeling and Machine Learning

Rejuan, R.; Aulisa, E.; Li, W.; Thompson, T.; Kumar, S.; Canic, S.; Wang, Y.

10.1101/2024.08.19.608572 — cancer biology — Posted on 2024-08-20

1957 Dynamins combine mechano-constriction and membrane remodeling to enable two-step mitochondrial fission via a snap-through instability.

Alimohamadi, H.; Luo, E. W.-C.; Yang, R.; Gupta, S.; Nolden, K.; Mandal, T.; Hill, R. B.; Wong, G. C. L.

10.1101/2024.08.19.608723 — biophysics — Posted on 2024-08-20

1958 A criterion characterizing accumulated toxicity of Aβ oligomers in Alzheimer's disease

Kuznetsov, A. V.

10.1101/2024.08.19.608707 — biophysics — Posted on 2024-08-20

1959 Multi-Modal Large Language Model Enables Protein Function Prediction

Huo, M.; Guo, H.; Cheng, X.; Singh, D.; Rahmani, H.; Li, S.; Gerlof, P.; Ideker, T.; Grotjahn, D. A.; Villa, E.; Song, L.; Xie, P.

10.1101/2024.08.19.608729 — bioinformatics — Posted on 2024-08-20

1960 The usage of transcriptomics datasets as sources of Real-World Data for clinical trialling

Matos-Filipe, P.; Garcia-Illarramendi, J. M.; Jorba, G.; Oliva, B.; Farres, J.; Mas, J. M.

10.1101/2022.11.10.515995 — bioinformatics — Posted on 2024-08-20

1961 Sawfish: Improving long-read structural variant discovery and genotyping with local haplotype modeling

Saunders, C. T.; Holt, J. M.; Baker, D. N.; Lake, J. A.; Belyeu, J. R.; Kronenberg, Z.; Rowell, W. J.; Eberle, M. A.

10.1101/2024.08.19.608674 — bioinformatics — Posted on 2024-08-20

1962 Towards Digital Quantification of Ploidy from Pan-Cancer Digital Pathology Slides using Deep Learning

Carrillo-Perez, F.; Cramer, E. M.; Pizurica, M.; Andor, N.; Gevaert, O.

10.1101/2024.08.19.608555 — bioinformatics — Posted on 2024-08-20

1963 Interdependent regulation of alternative splicing by SR and hnRNP proteins

Holmes, M. E.; Hertel, K. J.

10.1101/2024.08.19.608666 — bioinformatics — Posted on 2024-08-20

1964 Calmodulin enhances mTORC1 signaling by preventing TSC2-Rheb binding

Amemiya, Y.; Ioi, Y.; Maki, M.; Shibata, H.; Takahara, T.

10.1101/2024.08.19.608556 — biochemistry — Posted on 2024-08-20

1965 Structural insights into the mechanism of phosphate recognition and transport by human XPR1

Liu, Z.

10.1101/2024.08.19.608714 — biochemistry — Posted on 2024-08-20

1966 Genetic heterogeneity induces nonadditive behavioural changes in Drosophila

Okuyama, T.; Sato, D. X.; Takahashi, Y.

10.1101/2024.08.19.608728 — animal behavior and cognition — Posted on 2024-08-20

1967 Enhancing Variant Calling in Whole Exome Sequencing (WES) Data Using Population-Matched Reference Genomes

Guo, S.; Huang, Z.; Zhang, Y.; He, Y.; Chen, X.; Wang, W.; Li, L.; Kang, Y.; Gao, Z.; Yu, J.; Du, Z.; Chu, Y.

10.1101/2024.08.19.608554 — genomics — Posted on 2024-08-20

1968 A single-molecule nanopore sequencing platform

Zhang, J.-Y.; Zhang, Y.; Wang, L.; Guo, F.; Yun, Q.; Zeng, T.; Yan, X.; Yu, L.; Cheng, L.; Wu, W.; Shi, X.; Chen, J.; Sun, Y.; Yang, J.; Guo, R.; Zhang, X.; Kong, L.; Wang, Z.; Yao, J.; Tan, Y.; Shi, L.; Zhao, Z.; Feng, Z.; Yu, X.; Li, C.; Zhan, W.; Ren, Y.; Yang, F.; Liu, Z.; Fan, G.; Zhong, W.; Li, D.; He, L.; Qi, Y.; Zhang, M.; Zhu, Y.; Chi, H.; Zhao, Z.; Wei, Z.; Song, Z.; Ju, Y.; Guo, R.; Xiao, L.; Lin, X.; Chen, L.; Yang, C.; Li, Q.; Wang, O.; Jin, X.; Ni, M.; Zhang, W.; Liu, L.; Gu, Y.; Wang, J.; Li, Y.; Xu, X.; Dong, Y.

10.1101/2024.08.19.608720 — genomics — Posted on 2024-08-20

1969 Latent generative modeling of long genetic sequences with GANs

Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Yelmen, B.; Jay, F.

10.1101/2024.08.07.607012 — genomics — Posted on 2024-08-20

1970 The effect of extended cold storage and the use of extenders on motility and swimming kinematics of shortnose sturgeon sperm

Melanson, K. H.; Litvak, M. K.

10.1101/2024.08.18.608476 — ecology — Posted on 2024-08-20

1971 Nup107 is a crucial regulator of Torso-mediated metamorphic transition in Drosophila melanogaster

Kawadkar, J.; Mishra, R. K.

10.1101/2024.08.19.608657 — developmental biology — Posted on 2024-08-20

1972 The structural basis for RNA slicing by human Argonaute2

Mohamed, A. A.; Wang, P. Y.; Bartel, D. P.; Vos, S. M.

10.1101/2024.08.19.608718 — molecular biology — Posted on 2024-08-20

1973 Pseudomonas aeruginosa population dynamics in a vancomycin-induced murine model of gastrointestinal carriage

Lebrun-Corbin, M.; Cheung, B.; Hullahalli, K.; dailey, k.; Bailey, K.; Waldor, M. K.; Wunderlink, R.; Bachta, K. E. R.; Hauser, A. R.

10.1101/2024.08.19.608679 — microbiology — Posted on 2024-08-20

1974 Blocking Toxin Function and Modulating the Gut Microbiota: Caffeic Acid and its Derivatives as Potential Treatments for Clostridioides difficile Infection

Guo, Y.; Zhang, Y.; Wang, G.; Liu, H.; Wang, J.; Deng, X.; He, L.; Qiu, J.

10.1101/2024.08.19.608683 — microbiology — Posted on 2024-08-20

1975 Multi-Omics Unveils Strain-Specific Neuroactive Metabolite Production Linked to Inflammation Modulation by Bacteroides and Their Extracellular Vesicles

yousuf, b.; Mottawea, W.; Esmail, G. A.; Nazemof, N.; Bouhlel, N. E.; Njoku, E.; Li, Y.; Zhang, X.; Minic, Z.; Hammami, R.

10.1101/2024.08.19.608651 — microbiology — Posted on 2024-08-20

1976 Coping switches stress evoked network disconnection to a new forebrain network state.

Durieux, L.; Herbeaux, K.; Totah, N. K.; Lecourtier, L.

10.1101/2024.08.19.607747 — neuroscience — Posted on 2024-08-20

1977 Optimizing magnetometers arrays and analysis pipelines for multivariate pattern analysis

Bezsudnova, Y.; Quinn, A. J.; Jensen, O.

10.1101/2023.09.21.558786 — neuroscience — Posted on 2024-08-20

1978 Functional Regrowth of Norepinephrine Axons in the Adult Mouse Brain Following Injury

Cooke, P. R.; Linden, D. J.

10.1101/2024.08.19.608684 — neuroscience — Posted on 2024-08-20

1979 Online movements reflect ongoing deliberation

Calalo, J. A.; Ngo, T. T.; Sullivan, S. R.; Strand, K.; Buggeln, J. H.; Lokesh, R.; Roth, A. M.; Carter, M. J.; Kurtzer, I. L.; Cashaback, J. G. A.

10.1101/2024.08.19.608669 — neuroscience — Posted on 2024-08-20

1980 Intermittent Theta Burst Stimulation Drives Bi-Directional Changes in Excitability in Prefrontal Cortex

Salimi, M.; Nazari, M.; Mishler, J.; Mishra, J.; Ramanathan, D.

10.1101/2024.08.19.608693 — neuroscience — Posted on 2024-08-20

1981 Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function

Calhoun, C. C. S.; Capps, M. E. S.; Muya, K.; Gannaway, W. C.; Martina, V.; Conklin, C. L.; Klein, M. C.; Webster, J.; Torija-Olson, E. G.; Thyme, S.

10.1101/2024.08.19.608697 — neuroscience — Posted on 2024-08-20

1982 The Brain Interactome of a Permissive Prion Replication Substrate

Arshad, H.; Eid, S.; Mehra, S.; Williams, D.; Kaczmarczyk, L.; Stuart, E.; Jackson, W. S.; Schmitt-Ulms, G.; Watts, J. C.

10.1101/2024.08.19.608704 — neuroscience — Posted on 2024-08-20

1983 Optimal methods for analyzing targeted pairwise knockout screens

Chou, J.; Anvar, N. E.; Elghaish, R.; Chen, J.; Hart, T.

10.1101/2024.08.19.608665 — systems biology — Posted on 2024-08-20

1984 Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension

Zhang, R.; Shi, S.; Jadhav, D. A.; Kim, N.; Brostek, A.; Forester, B. R.; Shukla, R.; Qu, C.; Kramer, B.; Garvin, J. L.; Kleyman, T. R.; Gonzalez-Vicente, A.

10.1101/2024.08.19.608663 — physiology — Posted on 2024-08-20

1985 Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

Tang, Y. J.; Xu, H.; Hughes, N. W.; Kim, S. H.; Ruiz, P.; Shuldiner, E. G.; Lopez, S. S.; Hebert, J. D.; Karmakar, S.; Andrejka, L.; Dolcen, N.; Boross, G.; Chu, P.; Detrick, C.; Pierce, S. E.; Ashkin, E. L.; Greenleaf, W.; Voss, A. K.; Thomas, T.; van de Rijn, M.; Petrov, D.; Winslow, M. M.

10.1101/2024.08.19.607671 — cancer biology — Posted on 2024-08-20

1986 Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds

Bortoluzzi, C.; Restoux, G.; Rouger, R.; Desnoues, B.; Petitjean, F.; Bosse, M.; Tixier-Boichard, M.

10.1101/2024.02.22.581528 — genomics — Posted on 2024-08-20

1987 A Human Biomimetic Intestinal Mucosa Model to Study Gastrointestinal Development and Disease

Dei, A.; Calitz, C.; Korsten, J.; Johannesson, N.; Freeze, E.; Eaves, A.; Stingl, J.; Condor, R. K.; Chang, W.; Pajkrt, D.; Wolthers, K. C.; Sridhar, A.; Simmini, S.

10.1101/2024.08.20.608742 — cell biology — Posted on 2024-08-20

1988 Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection

Bosmani, C.; Perret, A.; Leuba, F.; Gueho, A.; Hanna, N.; Soldati, T.

10.1101/2024.08.19.608731 — cell biology — Posted on 2024-08-20

1989 Two paralogues of N-ethylmaleimide sensitive factor: An exception to the minimal vesicular trafficking machinery of Giardia

Ghosh, T.; Datta, S. P.; Mandal, P.; Patra, N.; Jana, K.; Ganguly, S.; Sarkar, S.

10.1101/2024.08.20.608744 — cell biology — Posted on 2024-08-20

1990 Confidence over competence: Real-time integration of social information in human continuous perceptual decision-making

Schneider, F.; Calapai, A.; Mundry, R.; Baez-Mendoza, R.; Gail, A.; Kagan, I.; Treue, S.

10.1101/2024.08.19.608609 — neuroscience — Posted on 2024-08-20

1991 Integrated multi-model analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD

Gonzalez Acera, M.; Patankar, J. V.; Erkert, L.; Cineus, R.; Gamey Belmonte, R.; Leupold, T.; Bubeck, M.; Bao, L.-l.; Dinkel, M.; Wang, R.; Limberger, H.; Stolzer, I.; Gerlach, K.; Mascia, F.; Koop, K.; Plattner, C.; Strurm, G.; Weigmann, B.; Guenther, C.; Wirtz, S.; Hildner, K.; Kuehl, A. A.; Siegmund, B.; Atreya, R.; The IBDome Consortium, ; Hegazy, A. N.; Trajanoski, Z.; Neurath, M. F.; Becker, C.

10.1101/2024.08.14.607902 — systems biology — Posted on 2024-08-20

1992 Heparanase 2 regulates endothelial permeability and prevents from proteinuria via VEGFA and FGF signaling

Becker, Y.; Tkachuk, S.; Jörns, A.; Alwakaa, A.; Hegermann, J.; Heiko, S.; Kiyan, Y.; Haller, H.

10.1101/2024.08.14.608012 — physiology — Posted on 2024-08-20

1993 GPRC6A is a Potential Therapeutic Target for Metformin Regulation of Glucose Homeostasis in Mice

Pi, M.; Agarwal, R.; Smith, M. D.; Smith, J. C.; Quarles, L. D.

10.1101/2024.08.19.608635 — physiology — Posted on 2024-08-20

1994 Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma

Yates, J.; Mathey-Andrews, C.; Park, J.; Garza, A.; Gagne, A.; Hoffman, S. E.; Bi, K.; Titchen, B.; Hennessey, C.; Remland, J.; Shannon, E. E.; Camp, S.; Balamurali, S.; Kiran Cavale, S.; Li, Z.; Kishore Raghawan, A.; Kraft, A.; Boland, G.; Aguirre, A. J.; Sethi, N.; Boeva, V.; Van Allen, E.

10.1101/2024.08.17.608386 — cancer biology — Posted on 2024-08-20

1995 The turbulent soundscape of intertidal oyster reefs

Volaric, M. P.; Stein, E. M.; Burtner, M.; Andrews, S. S.; Berg, P.; Reidenbach, M. A.

10.1101/2024.08.15.608049 — biophysics — Posted on 2024-08-20

1996 Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations

De La Forest Divonne, S.; Pouzadoux, J.; Romatif, O.; Montagnani, C.; Mitta, G.; Destoumieux-Garzon, D.; Gourbal, B.; Charriere, G. M.; Vignal, E.

10.1101/2024.07.19.604245 — immunology — Posted on 2024-08-20

1997 Cell size and selection for stress-induced binary cell fusion

Liu, X.; Pitchford, J. W.; Constable, G. W. A.

10.1101/2024.08.19.608569 — evolutionary biology — Posted on 2024-08-20

1998 Novel quantal analysis method reveals conservation of average charge injected by excitatory synapses across cortical neurons of different sizes

Dervinis, M.; Major, G.

10.1101/2024.07.05.602190 — neuroscience — Posted on 2024-08-20

1999 A novel method for reliably measuring miniature and spontaneous postsynaptic potentials/currents in whole-cell patch clamp recordings in the central nervous system

Dervinis, M.; Major, G.

10.1101/2022.03.20.485046 — neuroscience — Posted on 2024-08-20

2000 Target of rapamycin (TOR) regulates CURLY LEAF (CLF) translation in response to environmental stimuli

Yihan, D.; Oubassou, E.-Z.; Hoffmann, E.; Zhang, W.; Uslu, V. V.; Berr, A.

10.1101/2024.06.28.601127 — plant biology — Posted on 2024-08-20

2001 Long-term tracking of social structure in groups of rats

Nagy, M.; Davidson, J. D.; Vasarhelyi, G.; Abel, D.; Kubinyi, E.; El Hady, A.; Vicsek, T.

10.1101/2023.03.18.533183 — animal behavior and cognition — Posted on 2024-08-20

2002 ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

Zhang, B.; Huang, S.; Guo, S.; Meng, Y.; Tian, Y.; Zhou, Y.; Chen, H.; Li, X.; Zhou, J.; Chen, W.

10.1101/2024.02.29.582862 — plant biology — Posted on 2024-08-20

2003 The inherent fragility of collective proliferative control

Caldwell, M. G.; Lander, A. D.

10.1101/2024.01.23.576783 — cancer biology — Posted on 2024-08-20

2004 Diverse Genotype-by-Weather Interactions in Switchgrass

MacQueen, A. H.; Zhang, L.; Smith, S. P.; Bonnette, J. E.; Boe, A. R.; Fay, P. A.; Fritschi, F. B.; Lowry, D. B.; Mitchell, R. B.; Rouquette, F. M.; Wu, Y.; Harpak, A.; Juenger, T. E.

10.1101/2021.08.19.456975 — genetics — Posted on 2024-08-20

2005 The molecular and cellular anatomy of a fetal programming defect: the impact of low protein diet on the developing kidney.

Short, K. M.; Tortelote, G. G.; Jones, L. K.; Diniz, F.; Edgington-Giordano, F.; Cullen-McEwen, L. A.; Schroeder, J.; Spencer, A.; Keniry, A.; Polo, J. M.; Bertram, J. F.; Blewitt, M. E.; Smyth, I. M.; El-dahr, S. S.

10.1101/2023.12.04.569988 — developmental biology — Posted on 2024-08-20

2006 Trust or doubt? Neural resonance based on facial expressions in a deception game reflected by frontal EEG activities.

He, D.

10.1101/2024.08.19.608645 — neuroscience — Posted on 2024-08-19

2007 Lipid discovery enabled by sequence statistics and machine learning

Christensen, P. M.; Martin, J.; Uppuluri, A.; Joyce, L. R.; Wei, Y.; Guan, Z.; Morcos, F.; Palmer, K.

10.1101/2023.10.12.562061 — microbiology — Posted on 2024-08-19

2008 Revisiting the role of cAMP in Drosophila aversive olfactory memory formation

Abe, T.; Yamazaki, D.; Hiroi, M.; Ueoka, Y.; Maeyama, Y.; Tabata, T.

10.1101/2023.06.26.545795 — neuroscience — Posted on 2024-08-19

2009 The multi-stage plasticity in the aggression circuit underlying the winner effect

Yan, R.; Wei, D.; Varshneya, A.; Shan, L.; Asencio, H. J.; Lin, D.

10.1101/2024.08.19.608611 — neuroscience — Posted on 2024-08-19

2010 Compressed higher-order structures facilitate human knowledge network learning

Ren, X.; Wang, M.; Qin, T.; Fang, F.; Li, A.; Luo, H.

10.1101/2024.08.19.608587 — neuroscience — Posted on 2024-08-19

2011 The developing hippocampus: Microstructural evolution through childhood and adolescence

Karat, B. G.; Genc, S.; Raven, E. P.; Palombo, M.; Khan, A. R.; Jones, D. K.

10.1101/2024.08.19.608590 — neuroscience — Posted on 2024-08-19

2012 Feminization of social play behavior depends on microglia

VanRyzin, J. W.; Marquardt, A. E.; McCarthy, M. M.

10.1101/2024.08.19.608675 — neuroscience — Posted on 2024-08-19

2013 Temperature fluctuations influence predictions of landscape-scale patterns of spruce budworm defoliation

Black, E. N.; Pureswaran, D. S.; Marshall, K. E.

10.1101/2024.08.19.608715 — zoology — Posted on 2024-08-19

2014 Conservation of imprinted expression across genotypes is correlated with consistency of imprinting across endosperm development in maize

Higgins, K. M.; Nyabashi, V. I.; Anderson, S. N.

10.1101/2024.08.16.608346 — plant biology — Posted on 2024-08-19

2015 An extraordinary larval-like teleost fish from the Eocene of Bolca

Davesne, D.; Carnevale, G.

10.1101/2024.08.19.608581 — paleontology — Posted on 2024-08-19

2016 IGPR-1 is phosphorylated on the immunoreceptor tyrosine-based motif, stimulates AKT pathway and supports melanoma growth

Rahimi, N.; Potluri, S.; Chitalia, V.

10.1101/2024.08.19.608690 — cancer biology — Posted on 2024-08-19

2017 Y chromosome linked UTY modulates sex differences in valvular fibroblast methylation in response to nanoscale extracellular matrix cues

Gorashi, R. M.; Baddour, T.; Chittle, S. J.; Velez, N. E. F.; Wenning, M. A.; Anseth, K. S.; Mestroni, L.; Pena, B.; Guo, P.; Aguado, B. A.

10.1101/2024.05.13.593760 — bioengineering — Posted on 2024-08-19

2018 MAASTY: A (dis)ordered copolymer for structural determination of human membrane proteins in native nanodiscs

pugh, c. f.; Praestegaard, K. F.; Feilen, L. P.; Borthwick, N. J.; Zivkovic, D.; de Lichtenberg, C.; Bolla, J. R.; Autzen, A. A. A.; Autzen, h. e.

10.1101/2024.08.19.608676 — biochemistry — Posted on 2024-08-19

2019 Machine learning reveals signatures of promiscuous microbial amidases for micropollutant biotransformations

Marti, T. D.; Schweizer, D.; Yu, Y.; Schaerer, M. R.; Probst, S. I.; Robinson, S. L.

10.1101/2024.08.09.606993 — biochemistry — Posted on 2024-08-19

2020 Expanding kinetoplastid genome annotation through protein structure comparison

Trinidad-Barnech, J. M.; Sotelo-Silveira, J.; Fernandez Do Porto, D.; Smircich, P.

10.1101/2024.08.07.607044 — genomics — Posted on 2024-08-19

2021 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-19

2022 A geographic history of human genetic ancestry

Grundler, M. C.; Terhorst, J.; Bradburd, G. S.

10.1101/2024.03.27.586858 — genetics — Posted on 2024-08-19

2023 Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction

Boocock, J.; Alexander, N.; Tapia, L. A.; Walter-McNeill, L.; Patel, S. P.; Munugala, C.; Bloom, J. S.; Kruglyak, L.

10.1101/2023.12.07.570640 — genetics — Posted on 2024-08-19

2024 Risk assessment during nest defense against three simulated predators by female northern house wrens (Troglodytes aedon aedon)

Eggleston, R. C.; Fornara, J. H.; Davis, K. M.; Dong, J.; Reichard, D. G.

10.1101/2023.02.01.526454 — evolutionary biology — Posted on 2024-08-19

2025 Homoploid Hybrid Speciation in a Marine Pelagic Fish Megalaspis cordyla (Carangidae)

Muto, N.; Su, Y.-C.; Hata, H.; Nguyen, Q. V.; Vilasri, V.; Ghaffar, M. A.; Babaran, R. P.

10.1101/2024.08.17.608424 — evolutionary biology — Posted on 2024-08-19

2026 Lower adaptive immunity in invasive Egyptian geese compared to sympatric native waterfowls

Messina, S.; Prueter, H.; Czirjak, G. A.; Costantini, D.

10.1101/2024.04.03.587943 — ecology — Posted on 2024-08-19

2027 Local nesting resources rather than floral food alter ground-nesting bee communities in grazed habitats

Collins, S. M.; Taylor, L. A.; Wright, K. W.; Lichtenberg, E. M.

10.1101/2024.08.19.608671 — ecology — Posted on 2024-08-19

2028 Selection shapes plant performance in a grassland biodiversity experiment

De Giorgi, F.; Durka, W.; Huang, Y.; Schmid, B.; Roscher, C.

10.1101/2024.08.19.608599 — ecology — Posted on 2024-08-19

2029 SYS-1/beta-catenin inheritance and regulation by Wnt-signaling during asymmetric cell division.

Valdes Michel, M. F.; Phillips, B. T.

10.1101/2023.07.21.550069 — developmental biology — Posted on 2024-08-19

2030 Bacterial cross-feeding can promote gene retention by lowering gene expression costs

Chuang, Y.-C.; Behringer, M. G.; Patton, G.; Bird, J. T.; Love, C. E.; Dalia, A. B.; McKinlay, J. B.

10.1101/2024.08.19.608702 — microbiology — Posted on 2024-08-19

2031 Genomic Correlates of Tailocin Sensitivity in Pseudomonas syringae

Baltrus, D. A.; Weaver, S.; Krings, L.; Nguyen, A. E.

10.1101/2023.04.24.538177 — microbiology — Posted on 2024-08-19

2032 Abundant and active community members respond to the diel cycle in hot spring phototrophic mats

Shelton, A. N.; Yu, F. B.; Grossman, A. R.; Bhaya, D.

10.1101/2024.08.19.608644 — microbiology — Posted on 2024-08-19

2033 Hepatic iNKT cells facilitate colorectal cancer metastasis by inducing a fibrotic niche in the liver

Nater, M.; Brügger, M. D.; Cecconi, V.; Pereira, P.; Forni, G.; Köksal, H.; Dimakou, D.; Herbst, M.; Calvanese, A. L.; Lucchiari, G.; Schneider, C.; Valenta, T.; van den Broek, M.

10.1101/2024.08.19.608250 — immunology — Posted on 2024-08-19

2034 Functional identification of soluble uric acid as an endogenous inhibitor of CD38

Wen, S.; Arakawa, H.; Yokoyama, S.; Shirasaka, Y.; Higashida, H.; Tamai, I.

10.1101/2023.06.03.543541 — immunology — Posted on 2024-08-19

2035 Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation.

Carter-Cusack, D.; Huang, S.; Keshvari, S.; Patkar, O.; Sehgal, A.; Allavena, R.; Byrne, R.; Morgan, P.; Bush, S. J.; Summers, K. M.; Irvine, K. M.; Hume, D. A.

10.1101/2024.07.30.605701 — immunology — Posted on 2024-08-19

2036 Contrastive learning explains the emergence and function of visual category-selective regions

Prince, J. S.; Alvarez, G. A.; Konkle, T.

10.1101/2023.08.04.551888 — neuroscience — Posted on 2024-08-19

2037 Trust or doubt? Neural resonance based on facial expressions in a deception game reflected by frontal EEG activities.

He, D.

10.1101/2024.08.19.608645 — neuroscience — Posted on 2024-08-19

2038 Molecular Visualization of Neuronal TDP43 Pathology In Situ

Erwin, A. L.; Chang, M. L.; Fernandez, M. G.; Attili, D.; Russ, J. E.; Sutanto, R.; Pinarbasi, E. S.; Bekier, M.; Brant, T. S.; Hahn, T.; Dykstra, M.; Thomas, D.; Baldridge, R. D.; Tank, E. M. H.; Li, X.; Barmada, S. J.; Mosalaganti, S.

10.1101/2024.08.19.608477 — neuroscience — Posted on 2024-08-19

2039 A collicular map for touch-guided tongue control

Ito, B. S.; Gao, Y.; Kardon, B.; Goldberg, J. H.

10.1101/2024.04.08.587629 — neuroscience — Posted on 2024-08-19

2040 Minimal exposures reveal visual processing priorities

Lanfranco, R. C.; Canales-Johnson, A.; Rabagliati, H.; Cleeremans, A.; Carmel, D.

10.1101/2021.10.06.462913 — neuroscience — Posted on 2024-08-19

2041 Stress Recovery Triggers Rapid Transcriptional Reprogramming and Activation of Immunity in Plants

Illouz-Eliaz, N.; Yu, J.; Swift, J.; Lande, K.; Jow, B.; Tuang, Z. K.; Lee, T.; Yaaran, A.; Castanon, R. G.; Nery, J. R.; Nobori, T.; Zait, Y.; Burdman, S.; Ecker, J. R.

10.1101/2023.02.27.530256 — plant biology — Posted on 2024-08-19

2042 Coral species-specific loss and physiological legacy effects are elicited by extended marine heatwave

Strand, E.; Wong, K.; Farraj, A.; Gray, S.; McMenamin, A.; Putnam, H. M.

10.1101/2023.09.18.558296 — physiology — Posted on 2024-08-19

2043 Induction of Ferroptosis by an Amalgam of Extracellular Vesicles and Iron Oxide Nanoparticles Overcomes Cisplatin Resistance in Lung Cancer

Paramanantham, A.; Asfiya, R.; Manjunath, Y.; Xu, L.; McCully, G.; Das, S.; Yang, H.; Kaifi, J. T.; Srivastava, A.

10.1101/2024.08.19.608664 — cancer biology — Posted on 2024-08-19

2044 Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project

Ge, Y.; Lu, J.; Puiu, D.; Revsine, M.; Salzberg, S. L.

10.1101/2024.05.24.595788 — cancer biology — Posted on 2024-08-19

2045 Metadichol an agonist/antagonist that expresses the Toll Like Receptor family in various Cancer Cell Lines and its potential Impact on Cancer Treatment

Raghavan, P. R.

10.1101/2024.08.18.608483 — cancer biology — Posted on 2024-08-19

2046 Implementation and calibration of spectroscopic single-molecule localization microscopy

Brenner, B.; Yeo, W.-H.; Lee, Y.; Kweon, J.; Sun, C.; Zhang, H. F.

10.1101/2024.08.15.608177 — bioengineering — Posted on 2024-08-19

2047 Selective inhibition of hsp90 paralogs: Uncovering the role of helix 1 in Grp94-selective ligand binding

Que, N. L. S.; Seidler, P. M.; Aw, W. J.; Chiosis, G.; Gewirth, D. T.

10.1101/2023.07.31.551342 — biochemistry — Posted on 2024-08-19

2048 Dimerization GAS2 mediates microtubule and F-actin crosslinking

An, J.; Imasaki, T.; Narita, A.; Niwa, S.; Sasaki, R.; Makino, T.; Nitta, R.; Kikkawa, M.

10.1101/2024.08.19.608523 — biochemistry — Posted on 2024-08-19

2049 The ZIP8 A391T Crohn's disease-linked risk variant induces colonic metal ion dyshomeostasis, microbiome compositional shifts, and inflammation

Yang, J. C.; Zhao, M.; Chernikova, D.; Arias-Jayo, N.; Zhou, Y.; Situ, J.; Gutta, A.; Chang, C.; Liang, F.; Lagishetty, V.; Jacobs, J. P.

10.1101/2024.08.19.608695 — genomics — Posted on 2024-08-19

2050 Clusters of deep intronic RbFox motifs regulate mammalian alternative splicing

Tessarollo, L.; Tomassoni-Ardori, F.; Palko, M. E.; Galloux, M.

10.1101/2024.08.19.608686 — genetics — Posted on 2024-08-19

2051 De-biased sparse canonical correlation for identifying cancer-related trans-regulated genes

Huey, N.; Dutta, D.; Laha, N.

10.1101/2024.08.15.608166 — genetics — Posted on 2024-08-19

2052 Rethinking large scale phylogenomics with PhyloToL 6, a flexible toolkit to enable phylogeny-informed data curation and analysis

Cote-L'Heureux, A. E.; Leleu, M.; Ani, G.; Gawron, R.; Katz, L. A.

10.1101/2024.08.19.607962 — evolutionary biology — Posted on 2024-08-19

2053 Feeding a rich diet supplemented with the translation inhibitor cycloheximide decreases lifespan and ovary size in Drosophila

Hwang, H. J.; Cox, R.

10.1101/2024.08.19.608713 — developmental biology — Posted on 2024-08-19

2054 RNA promotes mitochondrial import of F1-ATP synthase subunit alpha (ATP5A1)

Chatterjee, A.; Noble, M.; Sekaran, T.; Ravi, V.; Appel, D. F.; Schwarzl, T.; Rampelt, H.; Hentze, M. W.

10.1101/2024.08.19.608659 — cell biology — Posted on 2024-08-19

2055 Topical ABT-1 263 treatment reduces aged skin senescence and improves subsequent wound healing

Shvedova, M.; Thanapaul, R. J. R. S.; Ha, J.; Dhillon, J.; Shin, G. H.; Crouch, J.; Gower, A. C.; Gritli, S.; Roh, D. S.

10.1101/2024.08.19.608670 — cell biology — Posted on 2024-08-19

2056 Cocaine-induced DNA-PK relieves RNAP II pausing by promoting TRIM28 phosphorylation.

Sharma, A. L.; Tyagi, P.; Khumallambam, M.; Tyagi, M.

10.1101/2024.08.19.608673 — molecular biology — Posted on 2024-08-19

2057 Renal proximal tubules are sensitive to metabolic acidosis

Hennings, J. C.; Murthy, K. S.; Picard, N.; Cabrita, I.; Boehm, D.; Krause, M. E.; Shah, V.; Baraka-Vidot, J.; Khundadze, M.; Stauber, T.; Boeckenhauer, D.; Jentsch, T. J.; Bachmann, S.; Schermer, B.; Eladari, D.; Chambrey, R.; Huebner, C. A.

10.1101/2024.08.19.608649 — molecular biology — Posted on 2024-08-19

2058 CTCF N-terminal Domain Regulates Clustered Protocadherin Gene Expression by Enhancing Cohesin Processivity

Zhang, Y.; Wu, Q.

10.1101/2024.08.19.608594 — molecular biology — Posted on 2024-08-19

2059 Recent Bovine HPAI H5N1 Isolate is Highly Virulent for Mice, Rapidly Causing Acute Pulmonary and Neurologic Disease

Tipih, T.; Mariappan, V.; Yinda, K. C.; Meade-White, K.; Lewis, M.; Okumura, A.; McCarthy, N.; Clancy, C.; de Wit, E.; Munster, V. J.; Feldmann, H. U.; Rosenke, K.

10.1101/2024.08.19.608652 — microbiology — Posted on 2024-08-19

2060 Vaccines combining slow delivery and follicle targeting of antigens increase germinal center B cell clonal diversity and clonal expansion

Rodrigues, K. A.; Zhang, Y.; Aung, A.; Morgan, D. M.; Maiorino, L.; Yousefpour, P.; Gibson, G.; Ozorowski, G.; Gregory, J. R.; Amlashi, P.; Buckley, M.; Ward, A. B.; Schief, W. R.; Love, J. C.; Irvine, D. J.

10.1101/2024.08.19.608655 — immunology — Posted on 2024-08-19

2061 Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Erkamp, N. A.; Farag, M.; Qiu, Y.; Qian, D.; Sneideris, T.; Wu, T.; Welsh, T. J.; Ausserwoger, H.; Krug, T. J.; Weitz, D.; Lew, M. D.; Knowles, T.; Pappu, R. V.

10.1101/2024.08.19.608662 — biophysics — Posted on 2024-08-19

2062 A c-opsin functions in a ciliary-marginal zone-like stem cell region of an invertebrate camera-type eye

Milivojev, N.; Gamboa, C. L. V.; Andreatta, G.; Raible, F.; Tessmar-Raible, K.

10.1101/2024.08.19.608633 — developmental biology — Posted on 2024-08-19

2063 Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading

Parmenter, A. L.; Newham, E.; Sharma, A.; Disney, C. M.; Deyhle, H.; Bosi, F.; Terrill, N. J.; Bay, B. K.; Pitsillides, A. A.; Gupta, H. S.; Lee, P. D.

10.1101/2024.08.19.608559 — bioengineering — Posted on 2024-08-19

2064 Ex situ spawning, larval development, and settlement in the massive reef-building coral Porites lobata in Palau

Bennett, M.-J.; Grupstra, C.; Da-Anoy, J.; Andres, M. O.; Holstein, D.; Rossin, A.; Davies, S. W.; Meyer-Kaiser, K.

10.1101/2024.08.19.608627 — ecology — Posted on 2024-08-19

2065 The consequences of mismatched buffers in spectral cell sorting

Dapaah, R. A. S.; Ferrer Font, L.; Shi, X.; Hall, C.; Thompson, S.; Catharina Costa, L.; Mage, P. L.; Tyznik, A. J.; Lundsten, K.; Walker, R. V.

10.1101/2024.08.19.608560 — cell biology — Posted on 2024-08-19

2066 Blockade of rheumatoid arthritis synovial fluid-induced sensory neuron activation by JAK inhibitors

Li, Y.; Gray, E. H.; Ross, R.; Zebochin, I.; Lock, A.; Fedele, L.; Kamajaya, L. J.; Marrow, R. J.; Ryan, S.; Röderer, P.; Brüstle, O.; John, S.; Denk, F.; Taams, L. S.

10.1101/2024.08.19.608613 — immunology — Posted on 2024-08-19

2067 CA1 ensemble plasticity is coupled to context change and modulated by task familiarity

Krajcovic, B.; Cernotova, D.; Stuchlik, A.; Kubik, S.; Svoboda, J.

10.1101/2024.08.19.608588 — neuroscience — Posted on 2024-08-19

2068 Genetic bioaugmentation-mediated bioremediation of terephthalate in soil microcosms using an engineered environmental plasmid

Marquiegui Alvaro, A.; Kottara, A.; CHACON, M.; Brockhurst, M.; Dixon, N.

10.1101/2024.08.19.608593 — synthetic biology — Posted on 2024-08-19

2069 Human PC4 supports telomere stability and viability in cells utilizing the alternative lengthening of telomeres mechanism

Salgado, S.; Abreu, P. L.; Moleirinho, B.; Larcombe, L.; Azzalin, C. M.

10.1101/2024.08.19.608623 — cancer biology — Posted on 2024-08-19

2070 Dissecting the oncogenic mechanisms of POT1 cancer mutations through deep scanning mutagenesis

Martin, A.; Schabort, J.; Bartke-Croughan, R.; Tran, S.; Preetham, A.; Lu, R.; Ho, R.; Gao, J.; Jenkins, S.; Boyle, J.; Ghanim, G. E.; Jagota, M.; Song, Y. S.; Li, H.; Hockemeyer, D.

10.1101/2024.08.19.608636 — cancer biology — Posted on 2024-08-19

2071 UnigeneFinder: An automated pipeline for gene calling from transcriptome assemblies without a reference genome

Xue, B.; Prado, K.; Rhee, S. Y.; Stata, M.

10.1101/2024.08.19.608648 — bioinformatics — Posted on 2024-08-19

2072 Deciphering of Gorilla gorilla gorilla Immunoglobulin Loci in Multiple Genome Assemblies and Enrichment of IMGT Resources

Debbagh, C.; Folch, G.; Jabado-Michaloud, J.; Giudicelli, V.; Kossida, S.

10.1101/2024.08.19.608532 — genomics — Posted on 2024-08-19

2073 What did the dove sing to Pope Gregory? Ancestral melody reconstruction in Gregorian chant using Bayesian phylogenetics.

Ballen, G. A.; Muhlova, K. H.; Hajic, J.

10.1101/2024.08.19.608653 — evolutionary biology — Posted on 2024-08-19

2074 Cell size and selection for stress-induced binary cell fusion

Liu, X.; Pitchford, J. W.; Constable, G. W. A.

10.1101/2024.08.19.608569 — evolutionary biology — Posted on 2024-08-19

2075 CH-related Mutant ASXL1 Promotes Atherosclerosis in Mice via Dysregulated Innate Immunity

Sato, N.; Goyama, S.; Chang, Y.-H.; Fujino, T.; Denda, T.; Asada, S.; Shikata, S.; Liu, X.; Yonezawa, T.; Takeda, R.; Yamamoto, K.; Tanaka, Y.; Honda, H.; Ota, Y.; Shibata, T.; Sekiya, M.; Koide, S.; Lamagna, C.; Masuda, E.; Iwama, A.; Shimano, H.; Inoue, J.-i.; Miyake, K.; Kitamura, T.

10.1101/2024.08.18.608516 — cell biology — Posted on 2024-08-19

2076 DHX15 inhibits mouse APOBEC3 deamination

Zhao, W.; Ross, S. R.

10.1101/2024.08.19.608612 — microbiology — Posted on 2024-08-19

2077 Histone lactylation: a new epigenetic mark in the malaria parasite Plasmodium

Jabre, I.; Andoh, N. E.; Naldoni, J.; Gregory, W. F.; Yoon, C. E.; Cunnington, A. J.; Georgiadou, A.; Blagborough, A. M.; Merrick, C. J.

10.1101/2024.08.19.608576 — microbiology — Posted on 2024-08-19

2078 Uncovering immune characteristics of neurons in the context of multiple sclerosis and experimental autoimmune encephalomyelitis

Mohammadnia, A.; Drake, S. S.; Zandee, S.; Gosselin, D.; Antel, J.; Prat, A.; Fournier, A.

10.1101/2024.08.19.608118 — neuroscience — Posted on 2024-08-19

2079 Burst Estimation through Atomic Decomposition (BEAD): A Toolbox to find Oscillatory Bursts in Brain Signals

Anand, A.; Murthy, C. R.; Ray, S.

10.1101/2024.08.19.608642 — neuroscience — Posted on 2024-08-19

2080 Peripheral Blood Immune Cells from Individuals with Parkinson's Disease or Inflammatory Bowel Disease Share Deficits in Iron Storage and Transport that are Modulated by Non-Steroidal Anti-Inflammatory Drugs

Bolen, M. L.; Gomes, B. N.; Gill, B.; Menees, K. B.; Staley, H.; Jernigan, J.; Tansey, M. G.

10.1101/2024.08.19.608634 — neuroscience — Posted on 2024-08-19

2081 Trust or doubt? Neural resonance based on facial expressions in a deception game reflected by frontal EEG activities.

He, D.

10.1101/2024.08.19.608645 — neuroscience — Posted on 2024-08-19

2082 Acute inhibition of iron-sulfur cluster biosynthesis disrupts metabolic flexibility in mice

Possemato, R.; Molenaars, M.; Mir, H.; Schmidt, A. M.; Arivazhagan, L.; Rosselot, C.; Garcia-Ocana, A.; Park, C.; Zhan, D.; Alvarez, S.

10.1101/2024.08.19.608291 — physiology — Posted on 2024-08-19

2083 Tumor-associated macrophages confer resistance to chemotherapy (Trifluridine/Tipiracil) in digestive cancers by overexpressing Thymidine Phosphorylase

Malier, M.; Laverriere, M.-H.; Henry, M.; Yakoubi, M.; Bellaud, P.; Arellano, C.; Sebillot, A.; Thomas, F.; Josserand, V.; Girard, E.; Roth, G.; MILLET, A.

10.1101/2024.08.19.608621 — pathology — Posted on 2024-08-19

2084 Comparative effects of proton and photon irradiation on the molecular and cellular profiles of triple-negative breast cancer: the crucial impact of VEGFC on tumor microenvironment remodeling

Sarlak, S.; Marotte, D.; Morfoisse, F.; Pierantoni, A.; Sirera, J.; Tsai, M.-C.; Vidal, M.; Herault, J.; Garmy-Susini, B.; Doyen, J.; Luciano, F.; Pages, G.

10.1101/2024.08.19.608614 — cancer biology — Posted on 2024-08-19

2085 Normalization of Single-cell RNA-seq Data UsingPartial Least Squares with Adaptive Fuzzy Weight

Singh, V.; Kirtipal, N.; Lim, S.; Lee, S.

10.1101/2024.08.18.608507 — bioinformatics — Posted on 2024-08-19

2086 Phytochemical Analysis and Cytotoxic Effects of Phyllanthus polygonoides Leaf Extracts on Hepatocellular Carcinoma: A Combined In-Vitro and In-Silico Approach

Khalid, A.; Akram, A.; Afzal, A.; Khalid, M. N.; Masroor, A.; Hameed, A.; Ali, H.

10.1101/2024.08.16.608215 — bioinformatics — Posted on 2024-08-19

2087 mobileRNA: a tool for efficient analysis of mobile RNA molecules in multiple genomes.

Jeynes-Cupper, K.; Catoni, M.

10.1101/2024.08.19.608270 — bioinformatics — Posted on 2024-08-19

2088 SegFinder: an automated tool for identifying RNA virus genome segments through co-occurrence in multiple sequenced samples

Liu, X.; Kong, J.; Shan, Y.; Yang, Z.; Miao, J.; Pan, Y.; Luo, T.; Shi, Z.; Wang, Y.; Gou, Q.; Yang, C.; Li, C.; Li, S.; Zhang, X.; Sun, Y.; Holmes, E. C.; Guo, D.; Shi, M.

10.1101/2024.08.19.608591 — bioinformatics — Posted on 2024-08-19

2089 Prediction of Adeno-Associated Virus Fitness with a Protein Language Based Machine Learning Model

Wu, J.; Qiu, Y.; Lyashenko, E.; Mueller, C.; Choudhury, S.

10.1101/2024.08.19.608620 — bioinformatics — Posted on 2024-08-19

2090 Discovering uncertainty: Bayesian constitutive artificial neural networks

Linka, K.; Holzapfel, G. A.; Kuhl, E.

10.1101/2024.08.19.608595 — bioengineering — Posted on 2024-08-19

2091 Computational simulations of hyoid bone position and tracheal displacement: Effects on upper airway patency and tissue mechanics

Bekdache, D.; Amatoury, J.

10.1101/2024.08.19.608628 — bioengineering — Posted on 2024-08-19

2092 Lung basement membranes are compositionally and structurally altered following resolution of acute inflammation.

Brand, O.; Kirkham, S.; Jagger, C.; Ozols, M.; Lennon, R.; Hussell, T.; Eckersley, A.

10.1101/2024.08.19.608567 — biochemistry — Posted on 2024-08-19

2093 Metabolic and Cellular Differences Between Sedentary and Active Individuals at Rest and During Exercise

San-Millan, I.; Martinez, J.; Sparagna, G.; D'Alessandro, A.; Stefanoni, D.; Nemkov, T.; Hill, J.

10.1101/2024.08.19.608601 — biochemistry — Posted on 2024-08-19

2094 Pumilio differentially binds to mRNA 3' UTR isoforms to regulate localization of synaptic proteins

Grzejda, D.; Hess, A.; Rezansoff, A.; Gorey, S.; Carrasco, J.; Alfonso-Gonzalez, C.; Tsagkris, S.; Neuhaus, L.; Ozbulut, H. C.; Voegtle, F.-N.; Vlachos, A.; Hilgers, V.

10.1101/2024.08.19.608606 — genomics — Posted on 2024-08-19

2095 Using Functional Genomic Data in Monocytes/Macrophages and Genotyping to Nominate Disease-Driving Single Nucleotide Polymorphisms and Target Genes in Juvenile Idiopathic Arthritis

Haley, E. K.; Barshad, G.; He, A.; Rice, E. J.; Sudman, M.; Thompson, S. D.; Crinzi, E. A.; Jiang, K.; Danko, C. G.; Jarvis, J. N.

10.1101/2024.08.19.608312 — genetics — Posted on 2024-08-19

2096 Phylogeographic Insights into Lion Evolution: Unraveling the Genetic Diversity and Lineage Divergence of Panthera leo

Amir Afzali, Y.

10.1101/2024.08.19.608589 — evolutionary biology — Posted on 2024-08-19

2097 Enhanced Diversifying Selection on Polymerase Genes in H5N1 Clade 2.3.4.4b: A Key Driver of Altered Species Tropism and Host Range Expansion

Misra, S.; Gilbride, E.; Ramasamy, S.; Pond, S. L. K.; Kuchipudi, S. V.

10.1101/2024.08.19.606826 — evolutionary biology — Posted on 2024-08-19

2098 Impactful feeding ecology of a predatory guild of oceanic jellies

Irvine, T.; Costello, J. H.; Gemmell, B.; Sutherland, K.; Colin, S.

10.1101/2024.08.19.608650 — ecology — Posted on 2024-08-19

2099 MicroEcoTools: an R package for comprehensive theoretical microbial ecology analysis

Neshat, S.; Santillan, E.; Wuertz, S.

10.1101/2024.08.19.608598 — ecology — Posted on 2024-08-19

2100 A maternally inherited Chromosomal Passenger Complex regulates germ plasm ribonucleoparticle aggregation in Zebrafish

Moravec, C.; Pelegri, F.

10.1101/2024.08.19.608573 — developmental biology — Posted on 2024-08-19

2101 Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons

Bendall, E. E.; Zhu, Y.; Fitzsimmons, W. J.; Rolfes, M.; Mellis, A.; Halasa, N.; Martin, E. T.; Grijalva, C. G.; Talbot, H. K.; Lauring, A. S.

10.1101/2024.08.15.608152 — microbiology — Posted on 2024-08-19

2102 Development of SacB-based Counterselection for Efficient Allelic Exchange in Fusobacterium nucleatum

Zhou, P.; G C, B.; Hu, B.; Wu, C.

10.1101/2024.08.16.608263 — microbiology — Posted on 2024-08-19

2103 Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant Staphylococcus aureus

Tran, M.; Viera, A. J. H.; Tran, P. Q.; Mo, C.

10.1101/2024.08.19.608629 — microbiology — Posted on 2024-08-19

2104 Variation in transformation frequency and competence gene expression among serotype 3 Streptococcus pneumoniae

Shambhu, S.; Cella, E.; Azarian, T.

10.1101/2024.08.19.608640 — microbiology — Posted on 2024-08-19

2105 Tim-3 promotes viral infection by suppressing USP25-TRAF3-IRF7 signaling pathway

Li, G.; Du, L.; Chen, J.; Du, C.; Chen, J.; Wang, C.; Bao, B.; LV, Z.; Xing, C.; Liang, M.; Wang, L.; Xie, S.; Li, Y.; Wang, Z.; Zhang, J.; Han, G.

10.1101/2024.08.19.608574 — immunology — Posted on 2024-08-19

2106 Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus 1 CNS infection

Ding, X.; Lei, X.; Klaestrup, I. H.; Jensen, S. R. N.; Nielsen, M. M.; Thorsen, K.; Romero-Ramos, M. R.; Luo, Y.; Lin, L.; Reinert, L. S.; Paludan, S. R.

10.1101/2024.08.19.608535 — immunology — Posted on 2024-08-19

2107 Malnutrition drives infection susceptibility and dysregulated myelopoiesis that persists after refeeding intervention

Sukhina, A.; Queriault, C.; Hall, E.; Rome, K.; Aggarwal, M.; Nunn, E.; Weiss, A.; Nguyen, J.; Bailis, W.

10.1101/2024.08.19.608575 — immunology — Posted on 2024-08-19

2108 The stretch-shortening cycle effect is not associated with cortical or spinal excitability modulations

Rissmann, L.-F.; Raiteri, B. J.; Seiberl, W.; Siebert, T.; Hahn, D.

10.1101/2024.08.19.608542 — neuroscience — Posted on 2024-08-19

2109 Context-sensitive processing in a model neocortical pyramidal cell with two sites of input integration

Graham, B. P.; Kay, J. W.; Phillips, W. A.

10.1101/2024.01.16.575982 — neuroscience — Posted on 2024-08-19

2110 Spontaneous network transitions predict somatosensory perception

Sharma, A.; Lange, J.; Vidaurre, D.; Florin, E.

10.1101/2023.10.19.563130 — neuroscience — Posted on 2024-08-19

2111 Fast implicit and slow explicit learning of temporal context in cortico-cerebellar loops

Mangili, L.; Wissing, C.; Narain, D.

10.1101/2024.08.19.608568 — neuroscience — Posted on 2024-08-19

2112 Lumped parameter simulations of cervical lymphatic vessels: dynamics of murine cerebrospinal fluid efflux from the skull

Kim, D.; Tithof, J.

10.1101/2024.05.24.595806 — neuroscience — Posted on 2024-08-19

2113 Cerebellar encoding of prior knowledge of temporal statistics

Koppen, J.; Bayones, L.; Runge, M.; Klinkhamer, I.; Narain, D.

10.1101/2024.08.19.608550 — neuroscience — Posted on 2024-08-19

2114 Phased chromosome-level genome assembly provides insight into the origin of hexaploid sweetpotato

Wu, S.; Sun, H.; Hamilton, J. P.; Mollinari, M.; Gesteira, G. D. S.; Kitavi, M.; Yan, M.; Wang, H.; Yang, J.; Yencho, G. C.; Buell, C. R.; Fei, Z.

10.1101/2024.08.17.608395 — plant biology — Posted on 2024-08-19

2115 Using lineage-specific patterns to understand convergence of enzymatic functions led to the identification of Moraceae-specific P450s involved in furanocoumarin biosynthesis

Bouille, A.; Rashmi Kumari, R.; Olry, A.; Charles, C.; Nelson, D. R.; Larbat, R.; Thornton, J.; Villard, C.; Hehn, A.

10.1101/2024.08.19.608558 — plant biology — Posted on 2024-08-19

2116 Developmental variability in cotton fiber cell wall properties linked to important agronomic traits

Wilson, M. C.; Howell, A. H.; Sood, A.; Lee, Y.; Yang, P.; Rani, H.; Yu, E.; Mallery, E. L.; Swaminathan, S.; Grover, C. E.; Wendel, J. F.; Zabotina, O. A.; Xie, J.; Davis, C. S.; Szymanski, D.

10.1101/2024.08.19.607249 — plant biology — Posted on 2024-08-19

2117 Network-based representation learning enables the identification of risk genes and latent functional pathways in primary open-angle glaucoma

Cousins, H. C.; Altman, R. B.; Pasquale, L. R.

10.1101/2024.08.15.608134 — bioinformatics — Posted on 2024-08-19

2118 Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe

stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.

10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-08-19

2119 Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

Poltavski, D. M.; Cunha, A. T.; Tan, J.; Sucov, H. M.; Makita, T.

10.1101/2024.02.13.580135 — developmental biology — Posted on 2024-08-19

2120 Chaotic dynamics for homeostatic hematopoiesis

Jia, D.; Cavazos, E. S.; West, T.; Liang, S.-H.; Costa, R.; Salomon, M. C.; Huang, A.; Trinchieri, G.; Lionakis, M.; Mukherjee, R.; Altan-Bonnet, G.

10.1101/2024.08.16.608266 — immunology — Posted on 2024-08-19

2121 Balancing Selectivity and Generality in Object Recognition through Structured Interconnectivity.

Yiyuan, Z.; Liu, J.; Liu, J.

10.1101/2024.08.17.608404 — neuroscience — Posted on 2024-08-19

2122 Using DeepLabCut-Live to probe state dependent neural circuits of behavior with closed-loop optogenetic stimulation

Gonzalez, M.; Gradwell, M. A.; Thackray, J. K.; Patel, K. R.; Temkar, K. K.; Abraira, V. E. G.

10.1101/2024.07.28.605489 — neuroscience — Posted on 2024-08-19

2123 A meta-analysis of sex differences in neonatal rodent ultrasonic vocalizations and the implication for the preclinical maternal immune activation model

Randell, A. M.; Salia, S.; Fowler, L. F.; Aung, T.; Puts, D.; Swift-Gallant, A.

10.1101/2024.08.19.608584 — neuroscience — Posted on 2024-08-19

2124 Learning to use landmarks for navigation amplifies their representation in retrosplenial cortex

Fischer, L. F.; Xu, L. Z.; Murray, K. T.; Harnett, M. T.

10.1101/2024.08.18.607457 — neuroscience — Posted on 2024-08-19

2125 Dopamine transients encode reward prediction errorsindependent of learning rates

Mah, A.; Golden, C. E. M.; Constantinople, C. M.

10.1101/2024.04.18.590090 — neuroscience — Posted on 2024-08-19

2126 New insights into the mechanisms of plant isotope fractionation from combined analysis of intramolecular 13C and deuterium abundances in Pinus nigra tree-ring glucose

Wieloch, T.; Holloway-Phillips, M.; Yu, J.; Niittyla, T.

10.1101/2024.02.21.581384 — plant biology — Posted on 2024-08-19

2127 Changes in SWEET-mediated sugar partitioning affect photosynthesis performance and plant response to drought

Aubry, E.; Clement, G.; Gilbault, E.; Dinant, S.; LE HIR, R.

10.1101/2024.04.12.589172 — plant biology — Posted on 2024-08-19

2128 Molecular and physiological characterization of tillering and shade tolerance of dwarf mutants of perennial ryegrass

kumar, R.; Yer, H.; Li, W.; Jiang, X.; Gai, Y.; Duan, H.; Li, Y.

10.1101/2024.08.18.606542 — plant biology — Posted on 2024-08-19

2129 An in-silico comparative analysis of lncRNA expression and their role in the pathogenesis of representative fungal, bacterial and viral infections in rice

Kandpal, M.; Sharma, M.; Rami, B. R.

10.1101/2024.08.18.608517 — plant biology — Posted on 2024-08-19

2130 Natural alleles of LEAFY and WAPO1 interact to regulate spikelet number per spike in wheat

Zhang, J.; Burguener, G. F.; Paraiso, F.; Dubcovsky, J.

10.1101/2024.08.17.608376 — plant biology — Posted on 2024-08-19

2131 A Deep Learning Framework for Predicting Prognostically Relevant Consensus Molecular Subtypes in HPV-Positive Cervical Squamous Cell Carcinoma from Routine Histology Images

Wang, R.; Gunesli, G.; Skingen, V. E.; Valen, K.-A. F.; Lyng, H.; Young, L.; Rajpoot, N.

10.1101/2024.08.16.608264 — pathology — Posted on 2024-08-19

2132 Mondrian Abstraction and Language Model Embeddings for Differential Pathway Analysis

Al Abir, F.; Chen, J. Y.

10.1101/2024.04.11.589093 — bioinformatics — Posted on 2024-08-19

2133 Intraperitoneal programming of tailored CAR macrophages via mRNA-LNP to boost cancer immunotherapy

Gu, K.; Liang, T.; Hu, L.; Zhao, Y.; Ying, W.; Zhang, M.; Chen, Y.; Liang, B.; Lin, X.; Zhang, Y.; Wu, H.; Wang, M.; Zhu, Y.; Wang, W.; Zhang, Y.; Zuo, C.; Du, Z.; Zhang, P.; Song, J.; Liu, X.; Xie, S.; Tan, W.

10.1101/2024.07.30.605730 — bioengineering — Posted on 2024-08-19

2134 AAV eluting lenses for single-step targeted expression of genetically- encoded activity sensors for in vivo microendoscopic calcium imaging

Jons, C.; Cheng, D.; Dong, C.; Meany, E. L.; Nassi, J.; Appel, E.

10.1101/2023.11.09.566491 — bioengineering — Posted on 2024-08-19

2135 The first assembled chromosome-level genome of an individual from Karnataka, India

mhatre, A.; Chindarkar, Y.; Ganesh, A.; Thakare, A.; Mishra, P.; Ravindran, F.; Sharma, A.; Srinivasan, S.; Choudhary, B.

10.1101/2024.08.18.608448 — genomics — Posted on 2024-08-19

2136 Thoracic Aortic 3-Dimensional Geometry: Effects of Aging and Genetic Determinants

Beeche, C.; Dib, M.-J.; Zhao, B.; Azzo, J.-D.; Maynard, H.; Duda, J.; Gee, J.; Salman, O.; Witschey, W.; Chirinos, J.

10.1101/2024.05.09.593413 — genomics — Posted on 2024-08-19

2137 Meta-analysis of the acoustic adaptation hypothesis reveals no support for the effect of vegetation structure on acoustic signalling across terrestrial vertebrates

Freitas, B.; D'Amelio, P. B.; Mila, B.; Thebaud, C.; Janicke, T.

10.1101/2024.02.21.581368 — evolutionary biology — Posted on 2024-08-19

2138 Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment

Urbancokova, A.; Hornofova, T.; Novak, J.; Salajkova, S. A.; Stemberkova Hubackova, S.; Uvizl, A.; Buchtova, T.; Mistrik, M.; Mac Stay, B.; Hodny, Z.; Bartek, J.; Vasicova, P.

10.1101/2023.08.05.552131 — cell biology — Posted on 2024-08-19

2139 LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARgamma Signaling

Xie, X.; Gao, M.; Zhao, W.; Li, C.; Zhang, W.; Yang, J.; Zhang, Y.; Chen, E.; Guo, Y.; Guo, Z.; Zhang, M.; Ngowi, E. E.; Wang, H.; Wang, X.; Zhu, Y.; Wang, Y.; Li, X.; Yao, H.; Yan, L.; Fang, F.; Li, M.; Qiao, A.; Liu, X.

10.1101/2024.03.22.586335 — molecular biology — Posted on 2024-08-19

2140 RNA tertiary structure and conformational dynamics revealed by BASH MaP

Oleynikov, M.; Jaffrey, S. R.

10.1101/2024.04.11.589009 — molecular biology — Posted on 2024-08-19

2141 Modelling interactions that determine core gut microbiome stability to predict microbiome perturbation by opportunistic pathogens

van Leeuwen, P. T.; Brul, S.; Seppen, J.; Wortel, M. T.

10.1101/2024.07.15.603569 — microbiology — Posted on 2024-08-19

2142 The glycolytic reaction PGAM unexpectedly restrains Th17 pathogenicity and Th17-dependent autoimmunity

Wang, C.; Wagner, A.; Fessler, J.; DeTomaso, D.; Zaghouani, S.; Zhou, Y.; Pierce, K.; Sobel, R. A.; Clish, C.; Yosef, N.; Kuchroo, V. K.

10.1101/2024.08.18.607992 — immunology — Posted on 2024-08-19

2143 Neural Mechanisms of Feedback Processing and Behavioral Adaptation during Neurofeedback Training

Pamplona, G. S. P.; Zweerings, J.; Lor, C. S.; deErney, L.; Roecher, E.; Taebi, A.; Hellrung, L.; Amano, K.; Scheinost, D.; Krause, F.; Rosenberg, M. D.; Ionta, S.; Brem, S.; Hermans, E.; Mathiak, K.; Scharnowski, F.

10.1101/2024.08.19.608543 — neuroscience — Posted on 2024-08-19

2144 Mathematical modeling unveils the timeline of CAR-T cell therapy and macrophage-mediated cytokine release syndrome

Santurio, D.; Barros, L. R.; Glauche, I.; Fassoni, A. C.

10.1101/2024.04.23.590738 — systems biology — Posted on 2024-08-19

2145 Interdependence of plasma membrane nanoscale dynamics of a kinase and its cognate substrate underlies Arabidopsis response to viral infection

Jolivet, M.-D.; Deroubaix, A.-F.; Boudsocq, M.; Abel, N. B.; Rocher, M.; Robbe, T.; Wattelet, V.; Huard, J.; Lefebvre, D.; Lu, Y.-J.; Day, B.; Saias, G.; Ahmed, J.; Cotelle, V.; Giovinazzo, N.; Gallois, J.-L.; Yamaji, Y.; German-Retana, S.; Gronnier, J.; Ott, T.; Mongrand, S.; Germain, V.

10.1101/2023.07.31.551174 — plant biology — Posted on 2024-08-19

2146 Identifiability of heterogeneous phenotype adaptation from low-cell-count experiments and a stochastic model

Browning, A. P.; Crossley, R. M.; Villa, C.; Maini, P. K.; Jenner, A. L.; Cassidy, T.; Hamis, S.

10.1101/2024.08.19.608540 — cancer biology — Posted on 2024-08-19

2147 Metadichol an agonist that expresses the entire Toll Like Receptor family in various Cancer Cell Lines and its potential Impact on Cancer Treatment

Raghavan, P. R. R.

10.1101/2024.08.18.608483 — cancer biology — Posted on 2024-08-19

2148 Development of Machine Learning-based QSAR Models for the Designing of Novel Anti-cancer Therapeutics Against Malignant Glioma

Asaad, F.; Zaka, M.; Durdagi, S.

10.1101/2024.08.19.608549 — bioinformatics — Posted on 2024-08-19

2149 LukProt: A database of eukaryotic predicted proteins designed for investigations of animal origins

Sobala, Łukasz F.

10.1101/2024.01.30.577650 — bioinformatics — Posted on 2024-08-19

2150 Improving the value utilization of tuna peptide powder for the cosmetics field through ozone oxidation

Zheng, H.; Gu, S.; Huang, S.; Zhang, Y.; Xu, F.; Lv, D.; Yuan, W.; Zhu, K.; Chen, X.

10.1101/2024.08.18.608506 — bioengineering — Posted on 2024-08-19

2151 Modeling of vascular interactions in endochondral ossification using human embryonic stem cells-derived organoid on a microfluidic chip

Kesharwani, A.; Tani, S.; Nishikawa, M.; Sakai, Y.; Okada, H.; Ohba, S.; Chung, U.-i.; Hojo, H.

10.1101/2024.08.18.608259 — bioengineering — Posted on 2024-08-19

2152 FindingNemo: A Toolkit for DNA Extraction, Library Preparation and Purification for Ultra Long Nanopore Sequencing

Cahyani, I.; Tyson, J.; Holmes, N.; Quick, J.; Moore, C.; Loman, N. J.; Loose, M. W.

10.1101/2024.08.16.608306 — genomics — Posted on 2024-08-19

2153 Mycn regulates vascular development through PI3K signaling pathway in zebrafish

Zhao, G.-Q.; Cheng, T.; Wang, P.-Y.; Mo, J.; Yu, F.; Dong, Y.; Li, Y.-F.; Feng, Y.; Xu, P.-F.; Shu, L.-P.

10.1101/2024.08.19.608563 — developmental biology — Posted on 2024-08-19

2154 Haploid Asexual Blastocyst Fitness Varies Across Mouse Strains Related to Efficiency of Exit From Totipotency

Crasta, D. N.; Lee, S. W.; Fredrickson, J.; Thejo, T.; Adiga, S. K.; Zhao, Y.; Kalthur, G.; Kannan, N.

10.1101/2024.08.19.608531 — developmental biology — Posted on 2024-08-19

2155 The exocyst complex controls multiple events in the pathway of regulated exocytosis.

Freire, S. S.; Perez-Pandolfo, S.; Fresco, S. M.; Valinoti, J.; Sorianello, E.; Wappner, P.; Melani, M.

10.1101/2023.08.31.555734 — cell biology — Posted on 2024-08-19

2156 Exploring 3-Aminobenzoic Acid as a Therapeutic Dietary Component for Enhancing Intestinal Barrier Integrity in Ulcerative Colitis

Tanaka, M.; Toyonaga, T.; Nakagawa, F.; Iwamoto, T.; Komatsu, A.; Sumiyoshi, N.; Shibuya, N.; Minemura, A.; Ariyoshi, T.; Matsumoto, A.; Oka, K.; Shimoda, M.; Saruta, M.

10.1101/2024.08.18.608525 — molecular biology — Posted on 2024-08-19

2157 Crystal structure and activity profiling of deubiquitinating inhibitors-bound to SARS-CoV-2 papain like protease revealed new allosteric sites for antiviral therapies

Choudhary, S.; Nehul, S.; Nagaraj, S. K.; Narayan, R.; Verma, S.; Sharma, S.; Kumari, A.; Rani, R.; Saha, A.; Sircar, D.; Tripathi, S.; Sharma, G. K.; Kumar, P.; Tomar, S.

10.1101/2022.11.11.516107 — molecular biology — Posted on 2024-08-19

2158 Navigating the Urban River: Transcriptomic Responses of Freshwater Fish to Multiple Anthropogenic Stressors

Escobar-Sierra, C.; Lampert, K. P.

10.1101/2024.08.19.608252 — molecular biology — Posted on 2024-08-19

2159 Interplay between chemotaxis, quorum sensing, and metabolism regulates Escherichia coli-Salmonella Typhimurium interactions in vivo

Laganenka, L.; Schubert, C.; Barthel, M.; Nguyen, B. D.; Naf, J.; Lobriglio, T.; Hardt, W.-D.

10.1101/2024.08.19.608533 — microbiology — Posted on 2024-08-19

2160 Electron tomography visualization of HIV-1 virions trapped by fusion inhibitors to host cells in infected tissues

Bjorkman, P. J.; Ladinsky, M. S.; Zhu, L.; Ullah, I.; Uchil, P. D.; Kumar, P.; Kay, M. S.

10.1101/2024.08.19.608557 — microbiology — Posted on 2024-08-19

2161 Early antiviral CD4 and CD8 T cell responses and antibodies are associated with upper respiratory tract clearance of SARS-CoV-2

Ramirez, S. I.; Lopez, P. G.; Faraji, F.; Parikh, U. M.; Heaps, A.; Ritz, J.; Moser, C.; Eron, J. J.; Wohl, D. A.; Currier, J. S.; Daar, E. S.; Greninger, A. L.; Klekotka, P.; Grifoni, A.; Weiskopf, D.; Sette, A.; Peters, B.; Hughes, M. D.; Chew, K. W.; Smith, D. M.; Crotty, S.; ACTIV-2/A5401 Study Team,

10.1101/2023.10.25.564014 — immunology — Posted on 2024-08-19

2162 Microbial metabolite-guided CAR T cell engineering enhances anti-tumor immunity via epigenetic-metabolic crosstalk

Staudt, S.; Nikolka, F.; Perl, M.; Franz, J.; Leblay, N.; Yuan, X.-K.; Warmuth, L.; Fantes, M. A.; Skorpskaite, A.; San Mrtin-Uriz, P.; Rodriguez-Madoz, J. R.; Ziegler-Martin, K.; Adil-Gholam, N.; Benz, P.; Tran Huu, P.; Stein-Thoeringer, C.; Schmitt, M.; Kleigrewe, K.; Freitag, F.; Riester, Z.; Weber, J.; Mangold, K.; Einsele, H.; Prosper, F.; Ellmeier, W.; Busch, D.; Visekruna, A.; Hiller, K.; van den Brink, M.; Pausch, P.; Neri, P.; Hudecek, M.; Poeck, H.; Luu, M.

10.1101/2024.08.19.608538 — immunology — Posted on 2024-08-19

2163 Deconstructing CTL-mediated autoimmunity through weak TCR-cross-reactivity towards highly abundant self-antigen

Plach, A.; Muhlgrabner, V.; Rodak, A.; Platzer, R.; Doel Perez, I.; Fellinger, P.; Peters, T.; Winhofer, Y.; Madritsch, C.; Schrangl, L.; Stockinger, H.; Dupre, L.; Busch, D. B.; Schober, K.; Gohring, J.; Huppa, J. B.

10.1101/2024.08.17.608371 — immunology — Posted on 2024-08-19

2164 Pemivibart is less active against recent SARS-CoV-2 JN.1 sublineages

Wang, Q.; Guo, Y.; Ho, J.; Ho, D. D.

10.1101/2024.08.12.607496 — immunology — Posted on 2024-08-19

2165 Attention and working memory investigated through the P300 component in children practicing Karate at different stages of biological maturation

Nicoliche, E.; Vasconcelos, A.; machado, m.; Tanaka, G.; Vicente, R.; Marques, A.; Costa, E.; Gongora, M.; Di Giacomo, J.; Nobre, M.; Teixeira, S.; Bastos, V.; Cagy, M.; Fernandes, I.; Machado, C.; Ribeiro, P.; Gupta, D.; Velasques, B.; Budde, H.

10.1101/2024.08.18.608511 — neuroscience — Posted on 2024-08-19

2166 Awe is characterized as an ambivalent experience in the human behavior and cortex: integrated virtual reality-electroencephalogram study

Yi, J.; Han, D. D.; Oh, S.-Y.; Cha, J.

10.1101/2024.08.18.608520 — neuroscience — Posted on 2024-08-19

2167 Network influence determines the impact of cortical ensembles on stimulus detection

Bounds, H. A.; Adesnik, H.

10.1101/2024.08.18.608496 — neuroscience — Posted on 2024-08-19

2168 GEARBOCS: An Adeno Associated Virus Tool for In Vivo Gene Editing in Astrocytes

Sivadasan Bindu, D.; Savage, J. T.; Brose, N.; Bradley, L.; Dimond, K.; Tan, C. X.; Eroglu, C.

10.1101/2023.01.17.524433 — neuroscience — Posted on 2024-08-19

2169 Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism

Lin, S.; Gade, A. R.; Wang, H.-G.; Niemeyer, J. E.; Galante, A.; DiStefano, I.; Towers, P.; Nunez, J.; Matsui, M.; Schwartz, T. H.; Rajadhyaksha, A.; Pitt, G. S.

10.1101/2024.04.18.590019 — neuroscience — Posted on 2024-08-19

2170 Golgi cells regulate timing and variability of information transfer in a cerebellar-behavioural loop

Palacios, E. R.; Houghton, C. J.; Chadderton, P.

10.1101/2024.07.10.602852 — neuroscience — Posted on 2024-08-19

2171 Two distinct oscillatory auxin signals define the plasticity of lateral rooting in Arabidopsis thaliana

Ren, C.; Bodendorf, J.; Kleine-Vehn, J.

10.1101/2024.08.16.608248 — plant biology — Posted on 2024-08-19

2172 Engineering rice Nramp5 modifies cadmium and manganese uptake selectivity using yeast assay system

Inoue, J.; Teramoto, T.; Kazama, T.; Nakamura, T.

10.1101/2024.08.18.605937 — plant biology — Posted on 2024-08-19

2173 Muscle Fibroblasts and Stem Cells Stimulate Motor Neurons in An Age and Exercise-Dependent Manner

Soendenbroe, C.; Schjerling, P.; Bechshoeft, C. J. L.; Svensson, R. B.; Schaeffer, L.; Kjaer, M.; Chazaud, B.; Jacquier, A.; Mackey, A. L.

10.1101/2024.08.19.608387 — physiology — Posted on 2024-08-19

2174 2-monopalmitin, but not 1-monopalmitin, enhances hypothalamic leptin responsiveness, energy balance, and glucose homeostasis under overnutrition

Takahashi, N.; Ikeda, M.; Yamazaki, Y.; Funatsu, Y.; Shiino, T.; Hosokawa, A.; Kaneko, K.

10.1101/2024.08.18.608432 — physiology — Posted on 2024-08-19

2175 Title: 4-week GLP immunotoxicity assessment of lactoferrin alpha produced by Komagataella phaffii in Sprague Dawley rats

Peterson, R.; Crawford, R. B.; Blevins, L. K.; Kaminski, N. E.; Clark, A. J.; Malinczak, C.-A.

10.1101/2024.08.16.608335 — pharmacology and toxicology — Posted on 2024-08-19

2176 Tanshinone IIA potentiates the therapeutic efficacy of glucocorticoid in lipopolysaccharide-treated HEI-OC1 cells through modulation of Foxp3/Nrf2 signaling pathway

Li, J.; Zhu, X.; Ye, S.; Dong, Q.; Hou, J.; Liu, J.; She, W.

10.1101/2024.08.19.608552 — pharmacology and toxicology — Posted on 2024-08-19

2177 DNA polymerase kappa stabilized by PTBP2 interacts with MRE11 and promotes genomic instability in leukemia cells

Lama, S.; Barik, B.; I.S., S.; Sarkar, T.; Chanda, S.; Behera, M.; Behera, S. P.; Biswas, S.; Mohapatra, S.; Biswas, G.; Chakraborty, S.

10.1101/2024.08.18.608437 — cancer biology — Posted on 2024-08-19

2178 Protection of the Telomeric Junction by the Shelterin Complex

Shiekh, S.; Feldt, D.; Jack, A.; Kodikara, S.; Alfehaid, J.; Pasha, S.; Yildiz, A.; Balci, H.

10.1101/2024.08.18.608453 — biophysics — Posted on 2024-08-19

2179 Automated Navigation of the lncRNA Transcriptome: A comprehensive SnakeMake based computational Pipeline for robust Identification of lncRNAs and their putative targets

Kandpal, M.; Mukherjee, C.; Rami, B. R.

10.1101/2024.08.18.608522 — bioinformatics — Posted on 2024-08-19

2180 High-Resolution Spatial Mapping of Electrocorticographic Activities with a 4096-Channel, Multiplexed Thin-Film Transistor Array

Sheng, X.

10.1101/2024.08.18.608446 — bioengineering — Posted on 2024-08-19

2181 Automatic detection of seizures within zebrafish larvae epilepsy models using single-channel electroencephalography

Delaney, C. M.; Wei, Q.; Peixoto, N.

10.1101/2024.08.18.608512 — bioengineering — Posted on 2024-08-19

2182 Suppression of glycolysis decreases sugar-induced cell death in Saccharomyces cerevisiae.

Valiakhmetov, A.

10.1101/2024.08.17.608408 — biochemistry — Posted on 2024-08-19

2183 Is there a right place? The effect of oviposition site selection on offspring survival in a glassfrog

Angiolani Larrea, F. N.; Valencia-Aguilar, A.; Garrido-Priego, M.; Culebras, J.; Peignier, M.; Jindiachi, L.; Tinajero-Romero, J. G.; Guayasamin, J. M.; Ringler, E.

10.1101/2024.08.18.608513 — animal behavior and cognition — Posted on 2024-08-19

2184 PanKB: An interactive microbial pangenome knowledgebase for research, biotechnological innovation, and knowledge mining

Sun, B.; Pashkova, L.; Pieters, P. A.; Harke, A. S.; Palsson, B. O.; Phaneuf, P. V.

10.1101/2024.08.16.608241 — genomics — Posted on 2024-08-19

2185 Trade-offs beget trade-offs: Causal analysis of mammalian population dynamics

Bergman, J.; Pedersen, R. O.; Lundgren, E. J.; Trepel, J.; Pearce, E. A.; Czyzewski, S.; Tietje, M.; Lemoine, R. T.; Coll Macia, M.; Schierup, M. H.; Svenning, J.-C.

10.1101/2024.08.16.608243 — evolutionary biology — Posted on 2024-08-19

2186 Dietary Analysis of Vespula shidai in Reared and Wild Nests

Saga, T.

10.1101/2024.08.18.608443 — ecology — Posted on 2024-08-19

2187 Instantaneous Flow Analysis of Contractile Cytoskeletal Structures Affected by the Dysregulation of Kinesin and Tropomyosin Motors

Matov, A.

10.1101/2024.06.28.601275 — cell biology — Posted on 2024-08-19

2188 Connectivity of the neuronal network for contextual fear memory is disrupted in a mouse model of third-trimester binge-like ethanol exposure

Morningstar, M. D.; Lopez, K. M.; Mayfield, S. S.; Almeida-Mancero, R. N.; Marquez, J.; Flores, A. M.; Hafer, B. R.; Estrada, E.; Holtzman, G. A.; Goranson, E. V.; Reid, N. M.; Aldrich, A. R.; Ghatalia, D. V.; Patel, J. R.; Padilla, C. M.; Chavez, G. J.; Roman, J. K.; Bhakta, P. A.; Valenzuela, C. F.; Linsenbardt, D. D.

10.1101/2024.08.16.608336 — neuroscience — Posted on 2024-08-19

2189 ROLE OF WORKING MEMORY IN INTERLIMB GENERALIZATION OF NEWLY LEARNED SKILLS

Yadav, G.; Pal, R.; Matkar, S.; Kumar, N.

10.1101/2024.08.17.608389 — neuroscience — Posted on 2024-08-19

2190 ClearScope: a fully integrated light sheet theta microscope for sub-cellular resolution imaging without lateral size constraints

Fay, M. G.; Lang, P. J.; Denu, D. S.; O'Connor, N. J.; Haydock, B. W.; Blaisdell, J. O.; Roussel, N.; Wilson, A. L.; Aronson, S. R.; Angstman, P. J.; Gong, C.; Butola, T.; Devinsky, O.; Basu, J.; Tomer, R.; Glaser, J. R.

10.1101/2024.08.15.608141 — neuroscience — Posted on 2024-08-19

2191 Engagement in moderate-intensity physical activity supports overnight emotional memory retention in older adults

Chappel-Farley, M. G.; Berisha, D. E.; Dave, A.; Sanders, R. M.; Kline, C. E.; Janecek, J. C.; Sattari, N.; Lui, K. K.; Chen, I. Y.; Neikrug, A. B.; Benca, R. M.; Yassa, M. A.; Mander, B. A.

10.1101/2024.08.16.608272 — neuroscience — Posted on 2024-08-19

2192 Manipulating rice canonical Gα and extra-large G protein subunits for improved agronomic traits

Cantos, C. F.; Assmann, S. M.

10.1101/2024.08.17.608385 — plant biology — Posted on 2024-08-19

2193 Xylazine Exacerbates Fentanyl-Induced Respiratory Depression and Bradycardia

Demery-Poulos, C.; Moore, S. C.; Levitt, E. S.; Anand, J. P.; Traynor, J. R.

10.1101/2024.08.16.608310 — pharmacology and toxicology — Posted on 2024-08-19

2194 Low hemoglobin causes hematoma expansion and poor intracerebral hemorrhage outcomes

Cottarelli, A.; Momoon, R.; Ji, R.; Mao, E.; Boehme, A. K.; Kumar, A.; Song, S.; Allegra, V.; Sharma, S. V.; Konofagou, E.; Spektor, V.; Guo, J.; Connolly, E. S.; Sekar, P.; Woo, D.; Roh, D. J.

10.1101/2024.08.15.608155 — pathology — Posted on 2024-08-19

2195 Pix2Path: Integrating Spatial Transcriptomics and Digital Pathology with Deep Learning to Score Pathological Risk and Link Gene Expression to Disease Mechanisms

Fu, X.; Chen, Y.

10.1101/2024.08.18.608468 — pathology — Posted on 2024-08-19

2196 Meta-analysis reveals limited reproducibility of lncRNA-related findings in hepatocellular carcinoma research

Necsulea, A.; Veber, P.; Boldanova, T.; Ng, C. K.; Wieland, S.; Heim, M. H.

10.1101/2024.08.17.608405 — cancer biology — Posted on 2024-08-19

2197 SUV39H1 Preserves Cancer Stem Cell Chromatin State and Properties in Glioblastoma

Li, C.; Xie, Q.; Ghosh, S.; Cao, B.; Du, Y.; Vo, G. V.; Huang, T. Y.; Spruck, C.; Wang, Y. A.; Nephew, K. P.; Shen, J.

10.1101/2024.08.15.607856 — cancer biology — Posted on 2024-08-19

2198 One-Pot Dual Protein Labelling for Simultaneous Mechanical and Fluorescent Readouts in Optical Tweezers

Silbermann, L.-M.; Fottner, M.; Migdad, N.; Lang, K.; Tych, K.

10.1101/2024.08.19.608605 — biophysics — Posted on 2024-08-19

2199 Dissecting contributions of pulmonary arterial remodeling to right ventricular afterload in pulmonary hypertension

Neelakantan, S.; Mendiola, E. A.; Vang, A.; Myers, K. J.; Zhang, P.; Choudhary, G.; Avazmohammadi, R.

10.1101/2024.08.18.608471 — bioengineering — Posted on 2024-08-19

2200 Dimerization GAS2 mediates microtubule and F-actin crosslinking

Jiancheng, A.; Imasaki, T.; Narita, A.; Niwa, S.; Sasaki, R.; Makino, T.; Nitta, R.; Kikkawa, M.

10.1101/2024.08.19.608523 — biochemistry — Posted on 2024-08-19

2201 Bacteriophages inject DNA into giant unilamellar vesicles mimicking Gram-negative lipopolysaccharide outer membranes

Stephan, M.; Broeker, N. K.; Robinson, T.; Dimova, R.; Barbirz, S.

10.1101/2024.08.19.608551 — biochemistry — Posted on 2024-08-19

2202 Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerisation on binding dsRNA.

Winterbourne, S. M.; Jayachandran, U.; Zou, J.; Rappsilber, J.; Granneman, S.; Cook, A. G.

10.1101/2024.08.19.607423 — biochemistry — Posted on 2024-08-19

2203 Low-cost animal tracking using Bluetooth low energy beacons on a crowd-sourced network

Farine, D. R.; Penndorf, J.; Bolcato, S.; Nyaguthii, B.; Aplin, L. M.

10.1101/2024.08.15.608178 — animal behavior and cognition — Posted on 2024-08-19

2204 High-speed whole-genome sequencing of a Whippet: Rapid chromosome-level assembly and annotation of an extremely fast dog's genome

Nebenfuehr, M.; Prochotta, D.; Ben Hamadou, A.; Janke, A.; Gerheim, C.; Betz, C.; Greve, C.; Bolz, H. J.

10.1101/2024.08.16.608262 — genomics — Posted on 2024-08-19

2205 Brain and gonadal genes are differentially expressed in Bicyclus anynana butterfly larvae that learned a heritable novel food odor preference

Gowri, V.; Tian, S.; Monteiro, A.

10.1101/2024.08.17.608425 — genomics — Posted on 2024-08-19

2206 Transgressive Hybrids as Hopeful Holobionts

Camper, B. T.; Kanes, A. S.; Laughlin, Z. T.; Manuel, R. T.; Bewick, S. A.

10.1101/2024.08.17.607925 — evolutionary biology — Posted on 2024-08-19

2207 Variations in flight strategy of small migratory birds crossing major ecological barriers

Dufour, P.; Nussbaumer, R.; Bocher, P.; Briedis, M.; Coulomb, Y.; Delacroix, R.; Dagonet, T.; de Franceschi, C.; de Grissac, S.; Jeannin, B.; Monchatre, R.; Rey, F.; Tillo, S.; Champagnon, J.; Duriez, O.; Jiguet, F.

10.1101/2024.08.18.608464 — ecology — Posted on 2024-08-19

2208 Species-specific interactions with apex carnivores yield unique benefits and burdens for mesocarnivores

Binder, W.; Rabe, J.; Lowe, Z.; Scott, G.; Lacey, C.; King, E.; Stahler, D. R.; Chakrabarti, S.

10.1101/2024.08.17.608414 — ecology — Posted on 2024-08-19

2209 Biological invasions forming intraguild predation communities in homogeneous and heterogeneous landscapes

Poloni Lyra, S.; Kraenkel, R. A.; Coutinho, R. M.

10.1101/2024.08.15.608146 — ecology — Posted on 2024-08-19

2210 ADAM interact with large protein complexes to regulate Histone modification, gene expression and splicing.

Pandey, A.; Cousin, H.; Kumar, S.; Taylor, L.; Chander, A.; Coppenrath, K.; Shaidani, N.-I.; Horb, M.; Alfandari, D.

10.1101/2024.08.18.608474 — developmental biology — Posted on 2024-08-19

2211 BMP signalling attenuates intercellular adhesion to drive mesenchyme migration during fin fold morphogenesis

Saha, B.; Mahabaleshwar, H.; Ho Min, C.; Leong, L. B. H.; Chua, L. W.; Kwok, S.; Carney, T. J.

10.1101/2024.08.18.608445 — developmental biology — Posted on 2024-08-19

2212 Three-dimension transcriptomics maps of whole mouse embryo during organogenesis

Cheng, M.; Zheng, H.; Fang, Q.; Bai, Y.; Liu, C.; Pan, H.; Zhang, Z.; Lu, Q.; Shi, C.; Xia, T.; Jing, Z.; Liu, H.; Feng, N.; Fu, G.; Li, Y.; Feng, J.; Li, Z.; Wang, J.; Chen, Y.; Wang, L.; Deng, Z.; Li, M.; Liu, L.; Chen, A.; Xu, X.

10.1101/2024.08.17.608366 — developmental biology — Posted on 2024-08-19

2213 C-C chemokine receptor 4 deficiency exacerbates early atherosclerosis in mice

Tanaka, T.; Sasaki, N.; Krisnanda, A.; Amin, H. Z.; Ito, K.; Horibe, S.; Matsuo, K.; Hirata, K.-i.; Nakayama, T.; Rikitake, Y.

10.1101/2024.08.16.608245 — immunology — Posted on 2024-08-19

2214 An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans

Kakade, P.; Burgueno, J. F.; Sircaik, S.; Ponde, N.; Li, J.; Ene, I. V.; Kim, J.; Liang, S.-H.; Yunker, R.; Akiba, Y.; Vaishnava, S.; Kaunitz, J. D.; Way, S. S.; Koh, A. Y.; Gaffen, S.; Abreu, M. T.; Bennett, R. J.

10.1101/2024.08.16.608271 — immunology — Posted on 2024-08-19

2215 Tissue determinants of the human T cell receptor repertoire.

Sureshchandra, S.; Henderson, J.; Levendosky, E.; Bhattacharyya, S.; Kastenschmidt, J. M.; Sorn, A. M.; Mitul, M. T.; Benchorin, A.; Batucal, K.; Daugherty, A.; Murphy, S. J.; Thakur, C.; Trask, D.; Ahuja, G.; Moisan, A.; Tiffeau-Mayer, A.; Saligrama, N.; Wagar, L. E.

10.1101/2024.08.17.608295 — immunology — Posted on 2024-08-19

2216 Macrophage WDFY3, a protector against autoimmunity

Wu, X.; Wang, Z.; Croce, K. R.; Li, F.; Cui, J.; D'Agati, V. C.; Soni, R.; Khalid, S.; Saleheen, D.; Tabas, I.; Yamamoto, A.; Zhang, H.

10.1101/2024.08.17.608411 — immunology — Posted on 2024-08-19

2217 A virtual clinical trial of psychedelics to treat patients with disorders of consciousness

Alnagger, N. L. N.; Cardone, P.; Martial, C.; Sanz Perl, Y.; Mindlin, I.; Sitt, J. D.; Roseman, L.; Carhart-Harris, R.; Nutt, D.; Mallaroni, P.; Mason, N. L.; Ramaekers, J. G.; Bonhomme, V.; Laureys, S.; Deco, G.; Gosseries, O.; Nunez, P.; Annen, J.

10.1101/2024.08.16.608251 — neuroscience — Posted on 2024-08-19

2218 Benchmarking macaque gene expression for horizontal and vertical translation

Luppi, A. I.; Liu, Z.-Q. I.; Hansen, J. Y.; Cofre, R.; Kuzmin, E. G.; Froudist-Walsh, S.; Palomero-Gallagher, N.; Misic, B.

10.1101/2024.08.18.608440 — neuroscience — Posted on 2024-08-19

2219 Characterization and analysis of neuronal signaling using microelectrode array combined with rapid and localized cooling device for cryo-neuromodulation

Kim, J.; Lee, J. S.; Noh, S.; Seo, E.; Lee, J.; Kim, T.; Cho, S.-W.; Kim, G.; Kim, S. S.; Park, J.

10.1101/2024.08.16.608362 — neuroscience — Posted on 2024-08-19

2220 Behavioral and Eye-Tracking Evidence for Disrupted Event Segmentation during Continuous Memory Encoding Due to Short Video Watching

Li, H.; Li, J.; Hao, X.; Liu, W.

10.1101/2024.08.17.608429 — neuroscience — Posted on 2024-08-19

2221 Platelet-derived LPA16:0 inhibits adult neurogenesis and stress resilience in anxiety disorder

Larrieu, T.; Carron, C.; Grieco, F.; Weber, C.; Ginggen, K.; Delacretaz, A.; Gallart-Ayala, H.; Tsuda, M.; Cameron, H.; Eap, C.; Ivanisevic, J.; Magistretti, P.; Telley, L.; Dayer, A.; Piguet, C.; Toni, N.

10.1101/2024.08.18.608479 — neuroscience — Posted on 2024-08-19

2222 Biological sex and BMI influence the longitudinal evolution of adolescent and young adult MRI-visible perivascular spaces

Yamamoto, E. A.; Koike, S.; Wong, C.; Dennis, L.; Luther, M. N.; Scatena, A.; Khambadkone, S.; Iliff, J.; Lim, M. M.; Levendovszky, S. R.; Elliott, J.; Barisano, G.; Muller-Oehring, E.; Morales, A. M.; Baker, F.; Nagel, B.; Piantino, J.

10.1101/2024.08.17.608337 — neuroscience — Posted on 2024-08-19

2223 Prefrontal Excitation/ Inhibition Balance Supports Adolescent Enhancements in Circuit Signal to Noise Ratio

McKeon, S. D.; Perica, M. I.; Calabro, F. J.; Foran, W.; Hetherington, H.; Moon, C.-H.; Luna, B.

10.1101/2024.08.15.608100 — neuroscience — Posted on 2024-08-19

2224 Neuronal basis of audio-tactile speech perception

Ciesla, K.; Wolak, T.; Amedi, A.

10.1101/2024.08.16.608369 — neuroscience — Posted on 2024-08-19

2225 An Infralimbic Cortex Neuronal Ensemble Encoded During Learning Attenuates Fear Generalization Expression

Subramanian, R.; Bauman, A.; Carpenter, O.; Cho, C.; Coste, G.; Dam, A.; Ehnstrom, S.; Fitzgerald, N.; Jenkins, A.; Koolpe, H.; Lui, R.; Paserman, T.; Petersen, D.; Chavez, D. S.; Rozental, S.; Thompson, H.; Tsukuda, T.; Zweig, S.; Gall, M.; Zupan, B.; Bergstrom, H.

10.1101/2024.08.18.608308 — neuroscience — Posted on 2024-08-19

2226 Ultra-low-field brain MRI morphometry: test-retest reliability and correspondence to high-field MRI

Vasa, F.; Bennallick, C.; Bourke, N. J.; Padormo, F.; Baljer, L.; Briski, U.; Cawley, P.; Arichi, T.; Wood, T. C.; Lythgoe, D. J.; Dell'Acqua, F.; Booth, T. C.; Venkataraman, A. V.; Ljungberg, E.; Deoni, S. C. L.; Moran, R. J.; Leech, R.; Williams, S. C. R.

10.1101/2024.08.14.607942 — neuroscience — Posted on 2024-08-19

2227 FORCE trained spiking networks do not benefit from fasterlearning while parameter matched rate networks do

Newton, T. R.; Nicola, W. R.

10.1101/2024.08.16.608322 — neuroscience — Posted on 2024-08-19

2228 Circadian clock in the lateral habenula affects motor function in mice through the regulation of daily rhythms in the nigrostriatal pathway

Goldfarb, C.; Baharav, N.; Jiang, H.; Szubinski, A.; Amir, S.; Schoettner, K.

10.1101/2024.08.17.608401 — neuroscience — Posted on 2024-08-19

2229 BundleAGE: Predicting White Matter Age using Along-Tract Microstructural Profiles from Diffusion MRI

Feng, Y.; Villalon-Reina, J. E.; Nir, T. M.; Chandio, B. Q.; Jahanshad, N.; Thompson, P. M.

10.1101/2024.08.16.608347 — neuroscience — Posted on 2024-08-19

2230 Measuring the effects of age on contrast suppression

Scott, M. T. W.; Wade, A. R.; Baseler, H. A.

10.1101/2024.08.16.608357 — neuroscience — Posted on 2024-08-19

2231 Entropy production constrains information throughput in gene regulation

Gehri, M.; Stelzl, L.; Koeppl, H.

10.1101/2024.08.17.608427 — systems biology — Posted on 2024-08-19

2232 Deep Learning and 3D Imaging Reveal Whole-Body Alterations in Obesity

Kaltenecker, D.; Horvath, I.; Al-Maskari, R.; Kolabas, Z. I.; Chen, Y.; Hoeher, L.; Todorov, M.; Kapoor, S.; Ali, M.; Kofler, F.; Morigny, P.; Geppert, J.; Jeridi, D.; Cigankova, C.; Kolenic, V. M.; Gur, N.; Pan, C.; Piraud, M.; Rueckert, D.; Rohm, M.; Hellal, F.; Elsner, M.; Bhatia, H. S.; Menze, B. H.; Herzig, S.; Paetzold, J. C.; Diaz, M. B.; Erturk, A.

10.1101/2024.08.18.608300 — systems biology — Posted on 2024-08-19

2233 Congruence between noise and plasticity in protein expression

Tsuru, S.; Furusawa, C.

10.1101/2024.08.18.608377 — systems biology — Posted on 2024-08-19

2234 Immunojanus Particles for low-volume and isolation-free unlabeled characterization of small Extracellular Vesicle in biofluids: Characterization of disease type by surface marker profiling

Kumar, S.; Sinclair, J. A.; Shi, T.; Chuang, H.-S.; Senapati, S.; Chang, H.-C.

10.1101/2024.08.17.607528 — scientific communication and education — Posted on 2024-08-19

2235 Flower bud cooling protects pollen development and improves fertility during heatwaves

Jansen, M. J.; Jansma, S. Y.; Kuipers, K. M.; Vriezen, W. H.; Millenaar, F. F.; Montoro, T.; de Kovel, C. G. F.; van Eeuwijk, F. A.; Visser, E. J. W.; Rieu, I.

10.1101/2024.08.18.608441 — plant biology — Posted on 2024-08-19

2236 Developmental plasticity and genetic selection shaped cereal evolution in the Early Holocene southern Levant

Whitlam, J.; Flohr, P.; Bogaard, A.; Charles, M.; Finlayson, B.; Makarewicz, C. A.

10.1101/2024.08.18.608467 — plant biology — Posted on 2024-08-19

2237 Intercellular compartmentation of trehalose 6-phosphate metabolism in Setaria viridis leaves

Tonetti, T.; Rojas, B. E.; Lucero, L. E.; Feil, R.; Calace, P.; Saigo, M.; Arrivault, S.; Stitt, M.; Lunn, J. E.; Figueroa, C. M.

10.1101/2024.08.16.608293 — plant biology — Posted on 2024-08-19

2238 Endothelial β1 Integrins are Necessary for Microvascular Function and Glucose Uptake

Winn, N. C.; Roby, D. A.; McClatchey, P. M.; Williams, I. M.; Bracy, D. P.; Bedenbaugh, M. N.; Lantier, L.; Plosa, E. J.; Pozzi, A.; Zent, R.; Wasserman, D. H.

10.1101/2024.08.18.607045 — physiology — Posted on 2024-08-19

2239 The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21

Xu, S.; Liu, Z.; Tian, T.; Zhao, W.; Wang, Z.; Liu, M.; Xu, M.; Zhang, F.; Zhang, Z.; Chen, M.; Yin, Y.; Su, M.; Pan, W.; Liu, S.; Li, M.-d.; Little, P.; Danielle Kamato, D.; Zhang, S.-y.; Wang, D.; Offermanns, S.; Speakman, J.; Weng, J.

10.1101/2024.08.18.608423 — pharmacology and toxicology — Posted on 2024-08-19

2240 Detection, Isolation and Quantification of Myocardial Infarct with Four Different Histological Staining Techniques

Wu, X.; Meier, L.; Liu, T.; Toldo, S.; Poelzing, S.; Gourdie, R. G.

10.1101/2024.08.16.608294 — pathology — Posted on 2024-08-19

2241 Dysregulated Cholesterol Metabolism with Anomalous PI3K/Akt/mTOR pathway Predicts Poor Carboplatin Response in High Grade Serous Ovarian Cancer

MAHAPATRA, E.; SAHA, A.; NAG, N.; GOPE, A.; THAKUR, D.; VERNEKAR, M.; CHAKRABARTI, J.; BASU, M.; PAL, A.; SENGUPTA, S.; MUKHERJEE, S.

10.1101/2024.08.17.608375 — cancer biology — Posted on 2024-08-19

2242 The CoREST complex is a therapeutic vulnerability in malignant peripheral nerve sheath tumors

Soukar, I.; Fisher, R.; Bhagavatula, S.; Collard, M.; Cole, P. A.; Alani, R. M.

10.1101/2024.08.17.607802 — cancer biology — Posted on 2024-08-19

2243 Cell states and neighborhoods in distinct clinical stages of primary and metastatic esophageal adenocarcinoma

10.1101/2024.08.17.608386 — cancer biology — Posted on 2024-08-19

2244 Chromosome breakage-replication/fusion enables rapid DNA amplification

Zhang, C.-Z.; Pellman, D.

10.1101/2024.08.17.608415 — cancer biology — Posted on 2024-08-19

2245 Outside-in engineering of cadherin endocytosis using a conformation strengthening antibody.

Xie, B.; Xu, S.; Sivasankar, S.

10.1101/2024.08.15.608168 — biophysics — Posted on 2024-08-19

2246 Essential Considerations for Free Energy Calculations of RNA-Small Molecule Complexes: Lessons from Theophylline-Binding RNA Aptamer

Rasouli, A.; Pickard, F. C.; Sur, S.; Grossfield, A.; Isık Bennett, M.

10.1101/2024.08.16.608304 — biophysics — Posted on 2024-08-19

2247 Evaluating the predictive accuracy of ion channel models using data from multiple experimental designs

Shuttleworth, J. G.; Lei, C. L.; Windley, M. J.; Hill, A. P.; Preston, S. P.; Mirams, G. R.

10.1101/2024.08.16.608289 — biophysics — Posted on 2024-08-19

2248 Low-cost and highly efficient generation of near-complete bacterial pathogen genomes by TELL-Seq

Wu, Z.; Zhang, T.; Li, S.; Shen, L.; Yang, Z.; Yang, Y.; Chen, X.; Li, B.; Zhou, S.; Zhou, X.; Wu, B.; Jiang, J.; Li, X.

10.1101/2024.08.17.608388 — bioinformatics — Posted on 2024-08-19

2249 DeepSomatic: Accurate somatic small variant discovery for multiple sequencing technologies

Park, J.; Cook, D. E.; Chang, P.-C.; Kolesnikov, A.; Brambrink, L.; Mier, J. C.; Gardner, J.; McNulty, B.; Sacco, S.; Keskus, A.; Bryant, A.; Ahmad, T.; Shetty, J.; Zhao, Y.; Tran, B.; Narzisi, G.; Helland, A.; Yoo, B.; Pushel, I.; Lansdon, L. A.; Bi, C.; Walter, A.; Gibson, M.; Pastinen, T.; Farooqi, M. S.; Robine, N.; Miga, K. H.; Carroll, A.; Kolmogorov, M.; Paten, B.; Shafin, K.

10.1101/2024.08.16.608331 — bioinformatics — Posted on 2024-08-19

2250 Creating and leveraging bespoke large-scale knowledge graphs for comparative genomics and multi-omics drug discovery with SocialGene

Clark, C. M.; Kwan, J. C.

10.1101/2024.08.16.608329 — bioinformatics — Posted on 2024-08-19

2251 Identifying drug-resistant individual cells within tumors by semi-supervised domain adaptation

Liu, H.; Huang, K.

10.1101/2024.08.18.608421 — bioinformatics — Posted on 2024-08-19

2252 Spatial Immunophenotyping from Whole-Slide Multiplexed Tissue Imaging Using Convolutional Neural Networks

Yosofvand, M.; Edmiston, S. N.; Smithy, J. W.; Peng, X.; Kostrzewa, C. E.; Lin, B.; Ehrich, F.; Reiner, A.; Miedema, J.; Moy, A. P.; Orlow, I.; Postow, M. A.; Panageas, K.; Seshan, V. E.; Callahan, M. K.; Thomas, N. E.; Shen, R.

10.1101/2024.08.16.608247 — bioinformatics — Posted on 2024-08-19

2253 Leveraging Machine Learning and AlphaFold2 Steering to Discover State-Specific Inhibitors Across the Kinome

Trozzi, F.; Tran, O.; Al Masri, C.; Lin, S.-H.; Ravikumar, B.; Rahman, R.

10.1101/2024.08.16.608358 — bioinformatics — Posted on 2024-08-19

2254 Classifying epithelial-mesenchymal transition states in single cell cancer data using large language models

Pan, S.; Withnell, E.; Secrier, M.

10.1101/2024.08.16.608311 — bioinformatics — Posted on 2024-08-19

2255 Y chromosome-coded HSATII repeats may contribute to higher incidence of cancer in men

Hegyi, H.; Lexa, M.

10.1101/2024.08.16.608341 — bioinformatics — Posted on 2024-08-19

2256 Evaluation of search-enabled Pre-trained Large Language Models on retrieval tasks for the PubChem Database

Sze, A.; Hassoun, S.

10.1101/2024.08.15.608120 — bioinformatics — Posted on 2024-08-19

2257 Correlating amino acid profiles with improved expression capability of superior CHO based expression platforms

Sharma, V.; Guleria, R.; Mukherjee, K. J.

10.1101/2024.08.16.608302 — bioengineering — Posted on 2024-08-19

2258 Function-first discovery of high affinity monoclonal antibodies using Nanovial-based plasma B cell screening

Challa, D.; de Rutte, J.; Konu, C.; Udani, S.; Liang, J.; Krohl, P. J.; Rondon, R.; Bondensgaard, K.; Di Carlo, D.; Watkins-Yoon, J.

10.1101/2024.08.15.608174 — bioengineering — Posted on 2024-08-19

2259 Rapid in situ forming PEG hydrogels for mucosal drug delivery

Yeruva, T.; Morris, R. J.; Zhao, L.; Kofinas, P.; Duncan, G. A.

10.1101/2024.08.16.608319 — bioengineering — Posted on 2024-08-19

2260 A Continuous, Low-Flow, and Multiplexing Pumping System for Microfluidics Applications

Walp, K. A.; Patel, Y. H.; Alsadoun, W.; Gordon, H. L.; Rastaghi, H.; M. D. Oliveira, S.

10.1101/2024.08.16.608339 — bioengineering — Posted on 2024-08-19

2261 Enhanced Piezoelectric Performance of PVDF-TrFE Nanofibers through Annealing for Tissue Engineering Applications

Krutko, M.; Poling, H. M.; Bryan, A.; Sharma, M.; Singh, A.; Al. Reza, H.; Wikenheiser-brokamp, K.; Takebe, T.; Helmrath, M.; Harris, G. M.; Esfandiari, L.

10.1101/2024.08.16.608345 — bioengineering — Posted on 2024-08-19

2262 Modulating Neutrophil Extracellular Trap Formation In Vivo with Locoregional Precision using Differently Charged Self-Assembled Hydrogels

Lopez-Silva, T. L.; Anderson, C. F.; Schneider, J. P.

10.1101/2024.08.16.608275 — bioengineering — Posted on 2024-08-19

2263 Dynamic Hydrogel Crosslink Strength Controls Yielding Characteristics and Cell Viability During Injection

Eckman, N.; Grosskopf, A. K.; Jiang, G.; Kamani, K.; Huang, M.; Schmittlein, B.; Heilshorn, S. C.; Rogers, S.; Appel, E.

10.1101/2024.08.16.608324 — bioengineering — Posted on 2024-08-19

2264 Dialogues in colour and behaviour - Integration of complex signalling traits and physiology

Patro, S.; Saravanan, T.; Parag, A.; Thaker, M.

10.1101/2024.08.16.608218 — animal behavior and cognition — Posted on 2024-08-19

2265 Mispitools: An R Package for Comprehensive Statistical Methods in Kinship Inference

Marsico, F.

10.1101/2024.08.16.608307 — genetics — Posted on 2024-08-19

2266 Extending the IICR to multiple genomes and identification of limitations of some demographic inferential methods

Chikhi, L.; Rodriguez, W.; Paris, C.; Ha-Shan, M.; Jouniaux, A.; Arredondo, A.; Nous, C.; Grusea, S.; Corujo, J.; Lourenco, I.; Boitard, S.; Mazet, O.

10.1101/2024.08.16.608273 — evolutionary biology — Posted on 2024-08-19

2267 A maximum likelihood estimator for quartets under the Cavender-Farris-Neyman model

Hill, M.; Rodriguez, J. I.

10.1101/2024.08.16.608292 — evolutionary biology — Posted on 2024-08-19

2268 Homoploid Hybrid Speciation in a Marine Pelagic Fish Megalaspis cordyla (Carangidae)

Muto, N.; Su, Y.-C.; Hata, H.; Nguyen, Q. V.; Ghaffar, M. A.; Vilasri, V.; Babaran, R. P.

10.1101/2024.08.17.608424 — evolutionary biology — Posted on 2024-08-19

2269 Sex differences and behaviour in the pace-of-life of rodents

Hughes, B.; Mastromonaco, G.; Bowman, J.; Schulte-Hostedde, A.

10.1101/2024.08.15.608175 — ecology — Posted on 2024-08-19

2270 The effect of extended cold storage and the use of extenders on motility and swimming kinematics of the sperm of shortnose sturgeon

Melanson, K. H.; Litvak, M. K.

10.1101/2024.08.18.608476 — ecology — Posted on 2024-08-19

2271 Benchmarking for the automated detection and classification of southern yellow-cheeked crested gibbon calls from passive acoustic monitoring data

Clink, D. J.; Cross-Jaya, H.; Kim, J.; Ahmad, A. H.; Hong, M.; Sala, R.; Birot, H.; Agger, C.; Vu, T. T.; Thi, H. N.; Chi, T. N.; Klinck, H.

10.1101/2024.08.17.608420 — ecology — Posted on 2024-08-19

2272 FSP1 stem/progenitor cells are essential for TMJ growth and homeostasis

Tuwatnawanit, T.; Wessman, W.; Belisova, D.; Sumbalova, Z.; Tucker, A. S.; Anthwal, N.

10.1101/2024.08.16.608236 — developmental biology — Posted on 2024-08-19

2273 Cell-free chromatin particles damage genomic DNA of healthy cells via an ROS-independent mechanism

Jain, K.; Raghuram, G. V.; Lopes, R.; Khare, N. K.; Shabrish, S.; Mittra, I.

10.1101/2024.08.16.608226 — cell biology — Posted on 2024-08-19

2274 Oncolytic vaccinia virus as a precision cancer vaccine platform

Komant, S. J.; Wang, J. L.; Favis, N.; Alex, C.; Evans, D. H.; Noyce, R. S.; Baldwin, T. A.

10.1101/2024.08.16.608170 — immunology — Posted on 2024-08-19

2275 Perinatal liver inflammation is associated with persistent elevation of CXCL10 and its canonical receptor CXCR3 on common myeloid progenitors

Alkhani, A.; Baskaran, S.; Murti, A.; Rapp, B.; Levy, C. S.; Wang, B.; Nijagal, A.

10.1101/2024.08.15.607661 — immunology — Posted on 2024-08-19

2276 Exercise-stimulated Resolvin Biosynthesis in Adipose Tissue is Abrogated by High Fat Diet-induced Adrenergic Deficiency

Pena Calderin, E. H.; Zheng, J.-J.; Boyd, N. L.; Lynch, W.; Sansbury, B. E.; Spite, M.; Hill, B. G.; Hellmann, J.

10.1101/2024.08.14.608014 — immunology — Posted on 2024-08-19

2277 An Image Processing Tool for Automated Quantification of Bacterial Burdens in Zebrafish Larvae

Yamaguchi, N.; Otsuna, H.; Eisenberg-Bord, M.; Ramakrishnan, L.

10.1101/2024.08.16.608298 — immunology — Posted on 2024-08-19

2278 Selective inhibition in CA3: A mechanism for stable pattern completion through heterosynaptic plasticity

Kim, G.; Kim, P.

10.1101/2024.08.16.608240 — neuroscience — Posted on 2024-08-19

2279 Metabolic connectivity has greater predictive utility for age and cognition than functional connectivity.

Deery, H. A.; Liang, E. X.; Moran, C.; Egan, G. F.; Jamadar, S. D.

10.1101/2024.08.15.608184 — neuroscience — Posted on 2024-08-19

2280 Moderate prenatal alcohol exposure alters GABAergic transmission and the action of acute alcohol in the CeM of adolescent rats

Winchester, S.; Diaz, M. R.

10.1101/2024.08.16.608070 — neuroscience — Posted on 2024-08-19

2281 Sapphire-Based Optrode for Low Noise Neural Recording and Optogenetic Manipulation

Xu, Y.; Li, B.-Z.; Huang, X.; Liu, Y.; Liang, Z.; Yang, X.; Lin, L.; Wang, L.; Xia, Y.; Ridenour, M.; Huang, Y.; Zhen, Y.; Klug, A.; Pun, S. H.; Lei, T. C.; Zhang, B.

10.1101/2024.08.15.608194 — neuroscience — Posted on 2024-08-19

2282 Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage

Geraghty, T.; Ishihara, S.; Obeidat, A. M.; Adamczyk, N. S.; Hunter, R. S.; Li, J.; Wang, L.; Lee, H.; Ko, F. C.; Malfait, A.-M.; Miller, R. E.

10.1101/2024.08.16.608301 — neuroscience — Posted on 2024-08-19

2283 Neural mechanisms of awareness of action

Jin, D. S.; Agdali, O.; Yadav, T.; Kronemer, S. I.; Kunkler, S.; Majumder, S.; Khurana, M.; McCusker, M. C.; Fu, I.; Khalaf, A.; Christison-Lagay, K. L.; Aerts, S. L.; Xin, Q.; Li, J.-J.; McGill, S. H.; Crowley, M. J.; Blumenfeld, H.

10.1101/2024.08.15.608153 — neuroscience — Posted on 2024-08-19

2284 Perisaccadic perceptual mislocalization strength depends on the visual appearance of saccade targets

Baumann, M. P.; Denninger, A. F.; Hafed, Z. M.

10.1101/2024.08.16.608354 — neuroscience — Posted on 2024-08-19

2285 Stabilizing microtubules aids neurite structure and disrupts syncytia formation in human cytomegalovirus-infected human forebrain neurons

Adelman, J. W.; Sukowaty, A. T.; Partridge, K. J.; Gawrys, J. E.; Terhune, S. S.; Ebert, A. D.

10.1101/2024.08.16.608340 — neuroscience — Posted on 2024-08-19

2286 Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer's disease mouse model

Dongre, P.; Ramesh, M.; Govindaraju, T.; Inamdar, M. S.

10.1101/2024.08.15.608066 — neuroscience — Posted on 2024-08-19

2287 Preparing to act follows Bayesian inference rules

Tarasi, L.; Tabarelli, C.; Covelli, M.; Ippolito, G.; Avenanti, A.; Romei, V.

10.1101/2024.08.16.608232 — neuroscience — Posted on 2024-08-19

2288 Novel Mouse Model of Alternating Hemiplegia of Childhood Exhibits Prominent Motor and Seizure Phenotypes

Hawkins, N.; DeKeyser, J.-M.; Kearney, J. A.; George, A. L.

10.1101/2024.08.18.608455 — neuroscience — Posted on 2024-08-19

2289 Target interception in virtual reality is better for natural versus unnatural trajectory shapes and orientations

Varon, S.; Babin, K.; Spering, M.; Culham, J. C.

10.1101/2024.08.16.607980 — neuroscience — Posted on 2024-08-19

2290 Ultraplex microscopy: versatile highly-multiplexed molecular labeling and imaging across scale and resolution

Perez-Garza, J.; Orea, J.; Deane, Z.; Raimondi, G.; Tripp, R.; Charles, I.; Ostroff, L.

10.1101/2024.08.17.605585 — neuroscience — Posted on 2024-08-19

2291 MiniXL: An open-source, large field-of-view epifluorescence miniature microscope for mice capable of single-cell resolution and multi-brain region imaging

Zhao, P.; Guo, C.; Xie, M.; Chen, L.; Golshani, P.; Aharoni, D.

10.1101/2024.08.16.608328 — neuroscience — Posted on 2024-08-19

2292 The Fragile X Messenger Ribonucleoprotein 1 regulates the morphology and maturation of human and rat oligodendrocytes

Ramesh, V.; Kougianou, I.; Tsoukala, E.; Kozic, Z.; Burr, K.; Viswanath, B.; Hampton, D.; Story, D.; Reddy, B. K.; Pal, R.; Dando, O. R.; Kind, P. C.; Chattarji, S.; Selvaraj, B. T.; Chandran, S.; Zoupi, L.

10.1101/2024.08.16.608069 — neuroscience — Posted on 2024-08-19

2293 Computational modeling of cancer cell metabolism along the catabolic-anabolic axes

Villela-Castrejon, J.; Levine, H.; Onuchic, J. N.; George, J. T.; Jia, D.

10.1101/2024.08.15.608169 — systems biology — Posted on 2024-08-19

2294 Recon8D: A metabolic regulome network from oct-omics and machine learning

Schildcrout, R.; Smith, K.; Bhowmick, R.; Menon, S.; Kapadia, M.; Kurtz, E.; Coffeen-Vandeven, A.; Chandrasekaran, S.

10.1101/2024.08.17.608400 — systems biology — Posted on 2024-08-19

2295 The longevity of cut flowers of Iranian narcissus is affected by genotype, physiochemical characteristics and stem structural factors

Haghshenas, A.; Jowkar, A.

10.1101/2024.08.16.608278 — plant biology — Posted on 2024-08-19

2296 A florigen-expressing subpopulation of companion cells expresses other small proteins and reveals a nitrogen-sensitive FT repressor

Takagi, H.; Ito, S.; Shim, J. S.; Kubota, A.; Hempton, A. K.; Lee, N.; Suzuki, T.; Yang, C.; Nolan, C. T.; Bubb, K. L.; Alexandre, C. M.; Kurihara, D.; Sato, Y.; Tada, Y.; Kiba, T.; Pruneda-Paz, J. L.; Queitsch, C.; Cuperus, J. T.; Imaizumi, T.

10.1101/2024.08.17.608367 — plant biology — Posted on 2024-08-19

2297 Conservation of imprinted expression across genotypes is correlated with consistency of imprinting across endosperm development in maize

Higgins, K. M.; Nyabashi, V. I.; Anderson, S. N.

10.1101/2024.08.16.608346 — plant biology — Posted on 2024-08-19

2298 Serum metabolomics signatures after an acute bout of combined traditional or high-intensity tactical training in young males and females

Graham, Z. A.; PATHAK, K. V.; Garcia-Mansfield, K.; Lavin, K.; Torres, A.; McAdam, J.; Broderick, T.; Pirrotte, P.; Bamman, M.

10.1101/2024.08.16.608249 — physiology — Posted on 2024-08-19

2299 14-3-3 promotes sarcolemmal expression of cardiac CaV1.2 and nucleates isoproterenol-triggered channel super-clustering

Spooner, H. C.; Costa, A. D.; Hernandez Gonzalez, A.; Ibrahimkhail, H.; Yarov-Yarovoy, V.; Horne, M.; Dickson, E. J.; Dixon, R. E.

10.1101/2024.08.16.607987 — physiology — Posted on 2024-08-19

2300 Evidence of persistent hyperphagia following a dietary weight-loss intervention in mice

Heyward, F. D.; Rosen, E. D.

10.1101/2024.08.16.608348 — physiology — Posted on 2024-08-19

2301 Main compounds in sweat, such as squalene and fatty acids, should be promising pheromone components for humans

Zhang, Y.-H.; Du, Y.-F.; Zhang, J.-X.

10.1101/2024.08.15.608030 — physiology — Posted on 2024-08-19

2302 Machine learning based identification of candidate miRNA biomarkers for micro-invasive breast cancer diagnosis

Pal, J. K.; Rami, B. R.

10.1101/2024.08.16.608025 — cancer biology — Posted on 2024-08-19

2303 Primary culture of high grade serous ovarian cancer cells, selection and derivation of three cell lines

Brenton, J. D.; Vias, M.; Sauer, C. M.; Funingana, G.; Piskorz, A. M.; Moore, E.; Chilamakuri, C.; Hall, D.; Goranova, T.; Van Oudenhove, E.; Earl, H. M.; Goldlust, I.

10.1101/2024.08.15.607946 — cancer biology — Posted on 2024-08-19

2304 A novel role for Neurog2 in MYCN driven neuroendocrine plasticity of prostate cancer

Walke, P.; Price, J. D.; Vizeacoumar, F. S.; Joseph, N.; Maranda, V.; Chowdhury, B.; Patel, J.; Zhang, Y.; Dong, H.; New, L.; Ganapathysamy, A.; Gong, L. H.; Elhasasna, H.; Bhanumathy, K. K.; Wu, Y.; Freywald, A.; Krishnan, A.; Vizeacoumar, F.

10.1101/2024.08.16.607954 — cancer biology — Posted on 2024-08-19

2305 Runx3 Acts as Homodimeric Chromatin Binding Factor Regulating Heterochromatin-Mediated Cancerous Phenotype

Mahmoud, S. A.; Bonne, I.; Sim, A. Y.; Abuelenain, G. L.

10.1101/2024.08.16.608297 — cancer biology — Posted on 2024-08-19

2306 How Modulation of the Tumor Microenvironment Drives Cancer Immune Escape Dynamics

Shrestha, P.; Ghoreyshi, Z.; George, J. T.

10.1101/2024.08.16.608314 — cancer biology — Posted on 2024-08-19

2307 Computational model of the human cochlea with motion of the layered osseous spiral lamina

Tubelli, A.; Secchia, P.; Nakajima, H. H.; Puria, S.

10.1101/2024.08.16.608342 — biophysics — Posted on 2024-08-19

2308 Enhanced spatially resolved transcriptomics analysis by matching between expression profiles and spatial topology

Pang, Y.; Wang, C.; Zhang, Y.-z.; Wang, Z.; Imoto, S.; Lee, T.-Y.

10.1101/2024.08.16.608230 — bioinformatics — Posted on 2024-08-19

2309 cytoKernel: Robust kernel embeddings for assessing differential expression of single cell data

Ghosh, T.; Baxter, R. M.; Seal, S.; Lui, V. G.; Rudra, P.; Vu, T.; Hsieh, E. W.; Ghosh, D.

10.1101/2024.08.16.608287 — bioinformatics — Posted on 2024-08-19

2310 Identifying unmeasured heterogeneity in microbiome data via quantile thresholding (QuanT)

Lu, J.; Satten, G. A.; Meyer, K. A.; Launer, L. J.; Ling, W.; Zhao, N.

10.1101/2024.08.16.608281 — bioinformatics — Posted on 2024-08-19

2311 Bioinformatics Copilot 2.0 for Transcriptomic Data Analysis

Wang, Y.; Zhang, W.; Wong, I.; Lin, S.; Kumar, R.; Wang, A.

10.1101/2024.08.15.607673 — bioinformatics — Posted on 2024-08-19

2312 Scupa: Single-cell unified polarization assessment of immune cells using the single-cell foundation model

Liu, W.; Zhao, Z.

10.1101/2024.08.15.608093 — bioinformatics — Posted on 2024-08-19

2313 Robustness and variability in Caenorhabditis elegans dauer gene expression

Corchado, J. C.; Godthi, A.; Selvarasu, K.; Prahlad, V.

10.1101/2024.08.15.608164 — bioinformatics — Posted on 2024-08-19

2314 The GenPPI tool enhanced Protein Interaction Network Generation with Machine Learning-Based Protein Similarity Inference

William, A.; Godoy, I.; Marquez, C.; Silva, L.; Prado, M.; Avila, N.; Santos, A. R. d.

10.1101/2024.08.16.608332 — bioinformatics — Posted on 2024-08-19

2315 Quantized multi-task learning for context-specific representations of gene network dynamics

Chen, H.; Venkatesh, M. S.; Gomez Ortega, J.; Mahesh, S. V.; Nandi, T. N.; Madduri, R. K.; Pelka, K.; Theodoris, C. V.

10.1101/2024.08.16.608180 — bioinformatics — Posted on 2024-08-19

2316 Contrastive learning for cell division detection and tracking in live cell imaging data

Zyss, D.; Sharma, A.; Ribeiro, S. A.; Repellin, C. E.; Lai, O.; Walter, T.; Fehri, A.

10.1101/2024.08.16.608296 — bioinformatics — Posted on 2024-08-19

2317 Metabolic engineering improves transduction efficiency and downstream vector isolation by altering the lipid composition of extracellular vesicle-enclosed AAV.

Espinoza, P.; Cheng, M.; Ng, C.; De La Cruz, D.; Wasson, E. D.; McCarthy, D. M.; Bhide, P. G.; Maguire, C. A.; Santoscoy, M. C.

10.1101/2024.08.16.608303 — bioengineering — Posted on 2024-08-19

2318 Speckle contrast optical spectroscopy improves cuffless blood pressure estimation compared to photoplethysmography

Garrett, A.; Kim, B.; Gurel, N. Z.; Sie, E. J.; Wilson, B. K.; Marsili, F.; Forman, J. P.; Hamburg, N. M.; Boas, D. A.; Roblyer, D.

10.1101/2024.08.16.608163 — bioengineering — Posted on 2024-08-19

2319 Whole-brain mapping in adult zebrafish and identification of a novel tank test functional connectome

Rajput, N.; Parikh, K.; Squires, A.; Fields, K. K.; Wong, M.; Kanani, D.; Kenney, J. W.

10.1101/2024.08.16.607981 — animal behavior and cognition — Posted on 2024-08-19

2320 Exploring ancestry inference of the Middle East

Herrick, N.; Ghemrawi, M.; Singh, S.; Mahfouz, R.; Walsh, S.

10.1101/2024.08.15.607793 — genetics — Posted on 2024-08-19

2321 De-biased sparse canonical correlation for identifying cancer-related trans-regulated genes

Huey, N.; Dutta, D.; Laha, N.

10.1101/2024.08.15.608166 — genetics — Posted on 2024-08-19

2322 Mutualisms within light microhabitats drive sensory convergence in a mimetic butterfly community

Wainwright, J. B.; Loupasaki, T.; Ramirez, F.; Penry-Williams, I. L.; England, S. J.; Barker, A.; Meier, J.; How, M. J.; Roberts, N. W.; Troscianko, J.; Montgomery, S. H.

10.1101/2024.08.16.607924 — evolutionary biology — Posted on 2024-08-19

2323 Novel use of global occurrence data to indirectly predict suitable habitats for widely distributed marine species in data-scarce regions

De Wysiecki, A. M.; Barnett, A.; Sanchez-Carnero, N. B.; Cortes, F.; Milessi, A. C.; Trobbiani, G. A.; Jaureguizar, A. J.

10.1101/2024.08.15.608095 — ecology — Posted on 2024-08-19

2324 Biodiversity and riparian forests are mutual biological drivers of ecosystem functions in temperate and tropical streams

Oester, R.; de Omena, P. M.; Corteletti da Costa, L.; Moretti, M.; Altermatt, F.; Bruder, A.

10.1101/2024.08.16.608233 — ecology — Posted on 2024-08-19

2325 The combined impact of climate change, pesticides and pharmaceuticals on life history and behaviour in killifish (Nothobranchius furzeri)

Kim, D.

10.1101/2024.08.15.608117 — ecology — Posted on 2024-08-19

2326 Insect size responses to climate changes vary across elevations according to seasonal timing

Nufio, C.; Sheffer, M.; Smith, J.; Troutman, M.; Bawa, S.; Taylor, E.; Schoville, S.; Williams, C.; Buckley, L.

10.1101/2024.08.15.608059 — ecology — Posted on 2024-08-19

2327 A simple inland culture system provides insights into ascidian post-embryonic developmental physiology

Mathiesen, B. T.; Ohta, M.; Magalhaes, B. P. D.; Castelletti, C.; Perria, V.; Christiaen, L.; Ohta, N.

10.1101/2024.08.16.608202 — developmental biology — Posted on 2024-08-19

2328 A human induced pluripotent stem (hiPS) cell model for the holistic study of epithelial to mesenchymal transitions (EMTs)

Hookway, C.; Borensztejn, A.; Harris, L. K.; Carlson, S.; Dalgin, G.; Mishra, S.; Nivedita, N.; Adams, E. M.; Barszczewski, T.; Dixon, J. C.; Edmonds, J. H.; Ehlers, E. A.; Ferrante, A. J.; Fuqua, M. A.; Garrison, P.; Gopalan, J.; Gregor, B. W.; Hedayati, M. J.; Klein, K. N.; Leveille, C. L.; Meharry, S. L.; Morris, H. S.; Nadarajan, G.; Oluoch, S. A.; Parent, S. E.; Phan, A.; Roberts, B.; Sanchez, E. E.; Sluzewski, M. F.; Snyder, L. S.; Thirstrup, D. J.; Thottam, J. P.; Torvi, J. R.; Turman, G.; Viana, M. P.; Wilhelm, L.; Wijesooriya, C. S.; Yao, J.; Theriot, J. A.; Rafelski, S. M.; Gunawarda

10.1101/2024.08.16.608353 — cell biology — Posted on 2024-08-19

2329 Investigating Polyreactivity of CD4+ T Cells to the Intestinal Microbiota

Saadawi, A.; Mair, F.; Rosenwald, E.; Hoces, D.; Slack, E.; Kopf, M.

10.1101/2024.08.15.607895 — immunology — Posted on 2024-08-19

2330 Glucose uptake in pigment glia suppresses tau-induced inflammation and photoreceptor degeneration in Drosophila

Oka, M.; Nakajima, S.; Suzuki, E.; Yamamoto, S.; Ando, K.

10.1101/2024.08.14.607919 — neuroscience — Posted on 2024-08-19

2331 Gut Microbiota and DTI Microstructural Brain Alterations in Rodents Due to Morphine Self-Administration

Brunetti, K.; Zhou, Z.; Shuchi, S.; Berry, R.; Zhang, Y.; Allen, M. S.; Yang, S.; Figueroa, J. D.; Colon-Perez, L.

10.1101/2024.08.15.608127 — neuroscience — Posted on 2024-08-19

2332 Population Representation of the Confidence in a Decision in the Lateral Intraparietal Area of the Macaque

Zylberberg, A.; Shadlen, M. N.

10.1101/2024.08.15.608159 — neuroscience — Posted on 2024-08-19

2333 Personalized whole-brain activity patterns predict human corticospinal tract activation in real-time

Khatri, U.; Pulliam, K.; Manesiya, M.; Cortez, M. V.; Millan, J. d. R.; Hussain, S.

10.1101/2024.08.15.607985 — neuroscience — Posted on 2024-08-19

2334 Comparison of test-retest reproducibility of DESPOT and 3D-QALAS for water T1 and T2 mapping

Simegn, G. L.; Gagoski, B.; Song, Y.; Dean, D. C.; Hupfelda, K. E.; Murali-Manohara, S.; Davies-Jenkinsa, C. W.; Simicic, D.; Wisnowskij, J.; Yedavallia, V.; Gudmundson, A. T.; Zollner, H. J.; Oeltzschner, G.; Edden, R. A. E.

10.1101/2024.08.15.608081 — neuroscience — Posted on 2024-08-19

2335 More similarity than difference: comparison of within- and between-sex variance in early adolescent brain structure

Torgerson, C.; Bottenhorn, K. L.; Ahmadi, H.; Choupan, J.; Herting, M. M.

10.1101/2024.08.15.608129 — neuroscience — Posted on 2024-08-19

2336 Sex differences in nucleus accumbens core circuitry engaged by binge-like ethanol drinking

Chan, A. E.; Anderson, J. Q.; Grigsby, K. E.; Jensen, B. E.; Ryabinin, A. E.; Ozburn, A. R.

10.1101/2024.08.15.608144 — neuroscience — Posted on 2024-08-19

2337 Could a female athlete run a 4-minute mile with improved aerodynamic drafting?

da Silva, E. S.; Hoogkamer, W.; Kipp, S.; Kram, R.

10.1101/2024.08.15.608172 — physiology — Posted on 2024-08-19

2338 Rapid and Sensitive Detection of Fusarium oxysporum f. sp. cubense Tropical Race 4 Using a RPA-DETECTR Assay

Venkatesh, J.; Jankowicz-Cieslak, J.; Mduma, H.; Matijevic, M.; Ali, A.; Calle Balbin, I. C.; Soto-Suarez, M.; Zorrilla, C.; Bhatnagar-Mathur, P.

10.1101/2024.08.15.608054 — pathology — Posted on 2024-08-19

2339 Restraint of melanoma progression by cells in the local skin environment

Ma, Y.; Tagore, M.; Hunter, M. V.; Huang, T.-H.; Montal, E.; Weiss, J. M.; White, R. M.

10.1101/2024.08.15.608067 — cancer biology — Posted on 2024-08-19

2340 The Identification of Key Genes and Biological Pathways in Cardiac Arrest by Integrated Bioinformatics and Next Generation Sequencing Data Analysis

Vastrad, B. M.; Vastrad, C. M.

10.1101/2024.08.15.608116 — bioinformatics — Posted on 2024-08-19

2341 CureSCi Metadata Catalog - finding and harmonizing studies for secondary analysis of hydroxyurea use for sickle cell disease

Wu, X.; Stratford, J.; Kesler, K.; Ives, C.; Hendershot, T.; Kroner, B.; Qin, Y.; Pan, H.

10.1101/2024.08.15.608203 — bioinformatics — Posted on 2024-08-19

2342 Eye-Opening Advances: Automated 3D Segmentation, Key Biomarkers Extraction, and the First Large-Scale MRI Eye Atlas.

Barranco Hernandez, J.; Luyken, A.; Kebiri, H.; Stachs, P.; Macias Gordaliza, P.; Esteban, O.; Aleman Gomez, Y.; Sznitman, R.; Stachs, O.; Langner, S.; Franceschiello, B.; Bach Cuadra, M.

10.1101/2024.08.15.608051 — bioengineering — Posted on 2024-08-19

2343 Dynamic assembly of pentamer-based protein nanotubes

Koziej, L.; Fatehi, F.; Aleksejczuk, M.; Byrne, M. J.; Heddle, J. G.; Twarock, R.; Azuma, Y.

10.1101/2024.08.15.608090 — bioengineering — Posted on 2024-08-19

2344 Using VR and eye-tracking to study attention to and retention of AI-generated ads in outdoor advertising environments

Lim, S.; Cho, H. J.; Jeon, M.; Cui, X.; Schmaelzle, R.

10.1101/2024.08.15.607684 — animal behavior and cognition — Posted on 2024-08-19

2345 Human Autosomal Nucleotide Positions Differing from Bonobo Instead Match Pig

McCarthy, E. M.

10.1101/2024.08.14.607926 — evolutionary biology — Posted on 2024-08-19

2346 Headwinds to Understanding Stress Response Physiology: A Systematic Review Reveals Mismatch between Real and Simulated Marine Heatwaves

Martell, H. A.; Donner, S. D.

10.1101/2024.08.15.608043 — ecology — Posted on 2024-08-19

2347 On the relationship between spatial environmental variability, dispersion and biodiversity

Bernardini, G.; Roberts, G. G.; Sutton, M. D.

10.1101/2024.08.15.608079 — ecology — Posted on 2024-08-19

2348 Behavioral plasticity and the valence of indirect interactions

Fahimipour, A. K.; Gil, M. A.; Hein, A. M.

10.1101/2024.08.15.608151 — ecology — Posted on 2024-08-19

2349 The Rab7-Epg5 and Rab39-ema modules cooperately position autophagosomes for efficient lysosomal fusions

Boda, A.; Balazs, V.; Nagy, A.; Hargitai, D.; Lippai, M.; Simon-Vecsei, Z.; Molnar, M.; Fürstenhoffer, F.; Juhasz, G.; Lörincz, P.

10.1101/2024.08.16.608254 — cell biology — Posted on 2024-08-19

2350 Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy

Lim, T. L.; Morral, C.; Verginadis, I. I.; Kim, K.; Luo, L.; Foley, C. J.; Kim, M. M.; Li, N.; Yoshor, B.; Njah, K.; Putt, M.; Oliaei Motlagh, S. A.; Velalopoulou, A.; Chowdhury, P.; Bicher, S.; Goia, D.; Lengner, C. J.; Wrana, J. L.; Koumenis, C.; Minn, A. J.

10.1101/2024.08.16.608284 — cell biology — Posted on 2024-08-19

2351 The Clonal Hematopoiesis-associated Gene Srcap Plays an Essential Role in Hematopoiesis

Wong, T. N.; Mychalowych, A.; Feldpausch, E. R.; Carson, A.; Karpova, D.; Link, D. C.

10.1101/2024.08.16.607812 — cell biology — Posted on 2024-08-19

2352 Berberine is a novel mitochondrial calcium uniporter (MCU) inhibitor that disrupts MCU-EMRE assembly

Zhao, H.; Chen, S.; Cao, N.; Wu, W.; Liu, G.; Gao, J.; Chen, J.; Li, T.; Lu, D.; Zeng, L.; Zhu, H.; Zhang, W.; Xia, Q.; Li, T.; Zhou, T.; Zhang, X.-M.; Li, A.-L.; Pan, X.

10.1101/2024.08.18.607892 — cell biology — Posted on 2024-08-19

2353 Uncovering Astrocyte Morphological Dynamics Using Optical Diffraction Tomography and Shape-based Trajectory Inference

Anantha, P.; Raj, P.; Saracino, E.; Kim, J. H.; Kim, J. H.; Convertino, A.; Gu, L.; Barman, I.

10.1101/2024.08.16.608356 — cell biology — Posted on 2024-08-19

2354 Differential cytoophidium assembly between Saccharomyces cerevisiae and Schizosaccharomyces pombe

Deng, R.; Li, Y.-L.; Liu, J.-L.

10.1101/2024.08.18.608450 — cell biology — Posted on 2024-08-19

2355 Low-level features predict perceived similarity for naturalistic images

A-Izzeddin, E. J.; Wallis, T. S. A.; Mattingley, J. B.; Harrison, W. J.

10.1101/2024.08.15.607867 — neuroscience — Posted on 2024-08-19

2356 Bidirectional Optogenetic Modulations of Peripheral Sensory Nerve Activity: Induction vs. Suppression through Channelrhodopsin and Halorhodopsin

Kosugi, A.; Inoue, K.-i.; Takada, M.; Seki, K.

10.1101/2024.08.15.608055 — neuroscience — Posted on 2024-08-19

2357 Boundary conditions for synaptic homeodynamics during the sleep-wake cycle

Kinoshita, F. L.; Yamada, R. G.; Ode, K. L.; Ueda, H. R.

10.1101/2024.08.14.607872 — neuroscience — Posted on 2024-08-19

2358 Combining Gamma Neuromodulation and Robotic Rehabilitation Restores Parvalbimin-mediated Gamma Function and Boosts Motor Recovery in Stroke Mice

Vignozzi, L.; Macchi, F.; Montagni, E.; Pasquini, M.; Martello, A.; Minetti, A.; Coulomb, E.; Allegra Mascaro, A. L.; Micera, S.; Caleo, M.; Spalletti, C.

10.1101/2024.08.15.608060 — neuroscience — Posted on 2024-08-19

2359 Aquaporin-4 mis-localization slows glymphatic clearance of α-synuclein and promotes α-synuclein pathology and aggregate propagation

Braun, M.; Simon, M. J.; Jang, J.; Sanderson, K.; Swierz, J.; Sevao, M.; Pincus, A. B.; Schaser, A. J.; Elliott, J. E.; Lim, M. M.; Unni, V. K.; Schindler, A. G.; Keene, C. D.; Latimer, C. S.; Iliff, J.

10.1101/2024.08.14.607971 — neuroscience — Posted on 2024-08-19

2360 Seeing the Future: Anticipatory Eye Gaze as a Marker of Memory

Yamin, D.; Schmidig, F. J.; Sharon, O.; Nadu, Y.; Nir, J.; Ranganath, C.; Nir, Y.

10.1101/2024.08.14.607869 — neuroscience — Posted on 2024-08-19

2361 LncRNA 3222401L13Rik Is Up-regulated in Aging Astrocytes and Regulates Neuronal Support Function Through Interaction with Npas3

Schroeder, S.; Sakib, M. S.; Krueger, D. M.; Pena, T.; Burkhardt, S.; Schuetz, A.-L.; Sananbenesi, F.; Fischer, A.

10.1101/2024.08.14.607966 — neuroscience — Posted on 2024-08-19

2362 The heat sensitivity of sperm in the lizard Anolis sagrei

Wang, W. W.-Y.; Gunderson, A. R.; Page, N. R.; Strickler, A. M.; Kusaka, A. K.

10.1101/2024.08.14.607821 — zoology — Posted on 2024-08-19

2363 Immune checkpoint inhibitor treatment does not impair ovarian or endocrine function in a mouse model of triple negative breast cancer

De La Cruz, P.; Woodman-Sousa, M. F.; McAdams, J. N.; Sweeney, E.; Hakim, L.; Morales Aquino, M.; Grive, K. J.

10.1101/2024.08.14.607933 — cancer biology — Posted on 2024-08-19

2364 Extracellular Vesicles heterogeneity through the lens of multiomics

Silva, T. F.; Hutchins, E.; Zhao, W.; Ciani, Y.; Kim, M.; Mariscal, J.; Qiu, Z.; Kittel, A.; Zhou, B.; Wang, Y.; Hall, M.; Galasso, F.; Reiman, R.; Freeman, M. R.; Parker, S.; Van Eyk, J.; Yang, W.; Posadas, E.; Guarnerio, J.; Nolan, J.; Thery, C.; Zijlstra, A.; Stott, S.; You, S.; Demichelis, F.; Boutros, P.; Van Keuren-Jensen, K.; Di Vizio, D.

10.1101/2024.08.14.607999 — cancer biology — Posted on 2024-08-19

2365 Harmonic representations of regions and interactions in spatial transcriptomics

Maher, K.; Wang, X.

10.1101/2024.08.14.607982 — bioinformatics — Posted on 2024-08-19

2366 The impact of channel geometry and flow regime on endothelial orientation and morphology in vessel-on-chip

Jouybar, M.; van der Kallen, S.; Sahebali, S.; Bouten, C.; den Toonder, J. M. J.

10.1101/2024.08.14.607791 — bioengineering — Posted on 2024-08-19

2367 Center of mass states render multi-joint torques throughout standing balance recovery

Jakubowski, K. L.; Martino, G.; Beck, O. N.; Sawicki, G. S.; Ting, L. H.

10.1101/2024.08.14.607976 — bioengineering — Posted on 2024-08-19

2368 Bio-macromolecular assembly machine for human limb lengthening

Xie, C.; Li, W.; Yao, X.; Wu, B.; Fang, J.; Mao, R.; Yan, Y.; Meng, H.; Wu, Y.; Zhang, X.; Duan, W.; Dai, X.; Wang, X.; Hongwei, O.

10.1101/2024.08.15.608028 — bioengineering — Posted on 2024-08-19

2369 Eltonian niche modelling: applying joint hierarchical niche models to ecological networks

Dehling, D. M.; Lai, H. R.; Stouffer, D. B.

10.1101/2024.08.14.607929 — ecology — Posted on 2024-08-19

2370 ER stress and mitochondrial dynamics: a tale of a wandering phosphatase DUSP28

Bhansali, P.; Gangi Setty, S. R.

10.1101/2024.08.17.608394 — cell biology — Posted on 2024-08-19

2371 Reconstituted high-density lipoproteins rescue diabetes-impaired endothelial cell metabolic reprograming and angiogenic responses to hypoxia

Primer, K. R.; Tan, J. T. M.; Sandeman, L.; Nankivell, V.; Stretton, L. G.; Solly, E.; Psaltis, P. J.; Bursill, C. A.

10.1101/2024.08.16.608361 — cell biology — Posted on 2024-08-19

2372 Dispersion indices for universal quantification of fluorescently-labelled subcellular structure spatial distributions

Grinstaff, M.; Martin, A.; Zhang, S.; Williamson, A.; Tingley, B.; Pickus, M.; Zurakowski, D.; Nia, H.; Shirihai, O. S.; Han, X. S.

10.1101/2024.08.18.608451 — cell biology — Posted on 2024-08-19

2373 An instantaneous voice synthesis neuroprosthesis

Wairagkar, M.; Card, N. S.; Singer-Clark, T.; Hou, X.; Iacobacci, C.; Hochberg, L. R.; Brandman, D. M.; Stavisky, S. D.

10.1101/2024.08.14.607690 — neuroscience — Posted on 2024-08-19

2374 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia

Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.

10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-19

2375 Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells

Sahu, S.; Castro, M.; Muldoon, J. J.; Asija, K.; Wyman, S. K.; Krishnappa, N.; de Onate, L.; Eyquem, J.; Nguyen, D. N.; Wilson, R. C.

10.1101/2024.07.14.603391 — bioengineering — Posted on 2024-08-19

2376 Polarization gratings aided common-path Hilbert holotomography for high-throughput lipid droplets content assay

Zdankowski, P.; Winnik, J.; Rogalski, M.; Marzejon, M. J.; Wdowiak, E.; Dudka, W.; Jozwik, M.; Trusiak, M.

10.1101/2024.06.14.598984 — bioengineering — Posted on 2024-08-19

2377 Characteristics of epitopes of limited variability on the head of influenza H1 haemagglutinin

Lourenco, J.; Zinad, H.; Kempton, J.; Gupta, S.

10.1101/2024.04.30.591841 — genomics — Posted on 2024-08-19

2378 DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice

Wang, X.; Shen, G.; Yang, Y.; Jiang, C.; Ruan, T.; Yang, X.; Zhuo, L.; Zhang, Y.; Ou, Y.; Zhao, X.; Long, S.; Tang, X.; Lin, T.; Shen, Y.

10.1101/2024.02.19.580977 — genetics — Posted on 2024-08-19

2379 The driving process for the evolutionay trajectory towards C4 photosynthesis

Yongyao, Z.; Yaoxin, Z.; Xinqi, Y.; Xinguang, Z.

10.1101/2024.04.26.591276 — evolutionary biology — Posted on 2024-08-19

2380 Repeated global adaptation across plant species

Nocchi, G.; Whiting, J. R.; Yeaman, S.

10.1101/2024.04.02.587814 — evolutionary biology — Posted on 2024-08-19

2381 Body mass change over winter is consistently sex-specific across roe deer (Capreolus capreolus) populations

Hewison, A. J. M.; Bonnot, N.; Gaillard, J.-M.; Kjellander, P.; Lemaitre, J.-F.; Morellet, N.; Pellerin, M.

10.1101/2022.09.09.507329 — ecology — Posted on 2024-08-19

2382 The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice.

Sakai, H.; Uno, H.; Yamakawa, H.; Tanaka, K.; Ikedo, A.; Uezumi, A.; Ohkawa, Y.; Imai, Y.

10.1101/2023.11.21.568190 — molecular biology — Posted on 2024-08-19

2383 Maternal prenatal stress induces sex-dependent changes in tRNA fragment families and cholinergic pathways in newborns

Vaknine Treidel, S.; Lobmaier, S.; Sharma, R.; Madrer, N.; Shulman, D.; Greenberg, P.; Bennett, E. R.; Greenberg, D. S.; Turjeman, A.; Zelgert, C.; Zimmermann, P.; Frasch, M. G.; Carmel, L.; Antonelli, M. C.; Soreq, H.

10.1101/2024.07.10.602894 — molecular biology — Posted on 2024-08-19

2384 A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota

Erickson, A. K.; Sutherland, D. M.; Welsh, O. L.; Maples, R. W.; Dermody, T. S.; Pfeiffer, J. K.

10.1101/2024.08.16.608258 — microbiology — Posted on 2024-08-19

2385 Overcoming off-target optical stimulation-evoked cortical activity in the mouse brain in vivo

Weiler, S.; Velez-Fort, M.; Margrie, T. W.

10.1101/2024.08.14.607152 — neuroscience — Posted on 2024-08-19

2386 Heterogeneous and non-random cortical connectivity undergirds efficient, robust and reliable neural codes

Egas Santander, D.; Pokorny, C.; Ecker, A.; Lazovskis, J.; Santoro, M.; Smith, J. P.; Hess, K.; Levi, R.; Reimann, M. W.

10.1101/2024.03.15.585196 — neuroscience — Posted on 2024-08-19

2387 Invariant synaptic density across species

Ferreira Castro, A.; Cardona, A.

10.1101/2024.07.18.604056 — neuroscience — Posted on 2024-08-19

2388 Toss GERALT into chloroplast to make it green: a new regulator of chloroplast biogenesis and chlorophyll biosynthesis

Banas, A. K.; Grzyb, J.; Zglobicki, P.; Pacak, A.; Mysliwa-Kurdziel, B.; Leja, K.; Kozieradzka-Kiszkurno, M.; Klodawska, K.; Konieczny, R.; Pilarska, M.; Niewiadomska, E.; Bazant, A.; Szewc, L.; Kowalska, E. B.; Strzalka, W.

10.1101/2024.08.16.608208 — plant biology — Posted on 2024-08-19

2389 Effect of 10 days of unilateral lower limb suspension on knee extensors neuromuscular function and spinal excitability

Lebesque, L.; Narici, M.; Martin, A.; De Vito, G.; Sarto, F.; Scaglioni, G.

10.1101/2024.03.06.583658 — physiology — Posted on 2024-08-19

2390 A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells

Babin-Ebell, A.; Mao, Y.; Baljkas, T.; Wiedmann, F.; Pilz, F.; Winkler, M.; Kuerschner-Zacharias, S. W.; Hoffarth, M.; Schmidt, C.; Goerdt, S.; Reiners-Koch, P.-S.; Singhal, M.

10.1101/2024.03.11.584492 — physiology — Posted on 2024-08-19

2391 Hybrid Exb/Mot stators require substitutions distant from the chimeric pore to power flagellar rotation

Ridone, P.; Baker, M. A.

10.1101/2024.03.12.584617 — microbiology — Posted on 2024-08-18

2392 Cell type and locus-specific epigenetic editing of memory expression

Coda, D. M.; WATT, L.; glauser, l.; Batiuk, M.; Burns, A.; Stahl, C.; Graeff, J.

10.1101/2024.08.18.608454 — neuroscience — Posted on 2024-08-18

2393 The potassium channel subunit KV1.8 (Kcna10) is essential for the distinctive outwardly rectifying conductances of type I and II vestibular hair cells

Martin, H. R.; Lysakowski, A.; Eatock, R. A.

10.1101/2023.11.21.563853 — neuroscience — Posted on 2024-08-18

2394 Loss of Zmiz1 in mice leads to impaired cortical development and autistic-like behaviors

K C, R.; Patel, N. R.; Thurmon, A. N.; Lorino, M. G.; Tiemroth, A. S.; Kulstad, I.; Morrison, V.; Akumuo, M.; Shenoy, A.; Meadows, S. M.; Galazo, M. J.

10.1101/2024.08.18.608498 — neuroscience — Posted on 2024-08-18

2395 Characterization of direct Purkinje cell outputs to the brainstem

Chen, C. H.; Yao, Z.; Wu, S.; Regehr, W. G.

10.1101/2024.08.16.608221 — neuroscience — Posted on 2024-08-18

2396 Task-related activity in auditory cortex enhances sound representation

Polterovich, A.; Jankowski, M. M.; Niediek, J.; Kazakov, A.; Nelken, I.

10.1101/2024.08.18.608392 — neuroscience — Posted on 2024-08-18

2397 Locus coeruleus activation 'resets' hippocampal event representations and separates adjacent memories

Clewett, D. V.; Huang, R.; Davachi, L.

10.1101/2024.08.15.608148 — neuroscience — Posted on 2024-08-18

2398 Prelimbic corticopontine neurons gate extinction learning

Lee, H.-R.; Choi, S. H.; Kim, Y.; Ko, S.; Kang, H.; Lee, I.; Park, A. J.; Lee, S.-H.

10.1101/2024.08.14.607871 — neuroscience — Posted on 2024-08-18

2399 FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device

Lin, B.; Du, H.; Yang, Y.; Hao, X.; Gao, F.; Liang, Y.; Tang, W.; Xu, H.; Tang, M.; Liao, Y.; Wang, D.; Lin, B.; Zhu, Y.; Wang, T.; Gu, R.; Miao, X.; He, Y.; Li, J.; zhou, z.; Wang, J.; Wu, D.; Du, X.

10.1101/2024.07.16.603758 — cancer biology — Posted on 2024-08-18

2400 Possible regulation of the immune modulator tetraspanin CD81 by alpha-synuclein in melanoma

Aloy, N. M.; Coughlan, C.; Graner, M. W.; Witt, S. N.

10.1101/2024.05.09.593218 — cancer biology — Posted on 2024-08-18

2401 MetaGXplore: Integrating Multi-Omics Data with Graph Convolutional Networks for Pan-cancer Patient Metastasis Identification

Jiang, T.; Jiang, H.; Ma, X.; Xu, M.; Zhang, W.

10.1101/2024.06.30.601445 — bioinformatics — Posted on 2024-08-18

2402 Protein Design by Directed Evolution Guided by Large Language Models

Tran, T. T.; Hy, T. S.

10.1101/2023.11.28.568945 — bioinformatics — Posted on 2024-08-18

2403 CellCover Captures Neural Stem Cell Progression in Mammalian Neocortical Development

Ji, L.; Wang, A.; Sonthalia, S.; Naiman, D. Q.; Younes, L.; Colantuoni, C.; Geman, D.

10.1101/2023.04.06.535943 — genomics — Posted on 2024-08-18

2404 Genetic predisposition towards multicellularity in Chlamydomonas reinhardtii

Chen, I.-C. K.; Khatri, S.; Herron, M. D.; Rosenzweig, F.

10.1101/2024.08.09.607418 — evolutionary biology — Posted on 2024-08-18

2405 Plant phenotypes as trajectories: 38-yr monitoring reveals that shape of lifetime fecundity schedule is under selection in a long-lived shrub

Herrera, C. M.

10.1101/2024.05.11.593670 — ecology — Posted on 2024-08-18

2406 Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning

Vellutini, B. C.; Martin-Duran, J. M.; Borve, A.; Hejnol, A.

10.1101/2023.09.03.556047 — developmental biology — Posted on 2024-08-18

2407 Live-Cell Quantification Reveals Viscoelastic Regulation of Synapsin Condensates by α-Synuclein

Wang, H.; Hoffmann, C.; Tromm, J. V.; Su, X.; Elliott, J.; Wang, H.; Baum, J.; Pang, Z. P.; Milovanovic, D.; Shi, Z.

10.1101/2024.07.28.605529 — cell biology — Posted on 2024-08-18

2408 Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms

Athanasiou, C.; Claveras Cabezudo, A.; Tsengenes, A.; Wade, R. C.

10.1101/2024.08.16.608237 — molecular biology — Posted on 2024-08-18

2409 Engineered transcription-associated Cas9 targeting in eukaryotic cells

Goldberg, G. W.; Kogenaru, M.; Keegan, S.; Haase, M. A. B.; Kagermazova, L.; Arias, M. A.; Onyebeke, K.; Adams, S.; Beyer, D. K.; Fenyo, D.; Noyes, M. B.; Boeke, J. D.

10.1101/2023.09.18.558319 — molecular biology — Posted on 2024-08-18

2410 Dietary Bioactive Compounds Trigger Distinct Epigenetic and Metabolic Reprogramming in Lactobacillus acidophilus

Kong, Y.; Adejoro, D. O.; Wescombe, P. A.; Winefield, C.; On, S. L. W.; Mitchell, N. L.; Subbaraj, A.; Saunders, A.; Maes, E.; Chelikani, V.

10.1101/2024.08.18.608491 — microbiology — Posted on 2024-08-18

2411 Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice

Nash, A. N.; Shakeshaft, M.; Bouaichi, C. G.; Odegaard, K. E.; Needham, T.; Bauer, M.; Bertram, R.; Vincis, R.

10.1101/2024.04.27.591293 — neuroscience — Posted on 2024-08-18

2412 Infant neural sensitivity to affective touch is associated with maternal postpartum depression

Nance, M. G.; Landsman, Z. T.; Gerling, G. J.; Puglia, M. H.

10.1101/2024.02.21.581204 — neuroscience — Posted on 2024-08-18

2413 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia

Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.

10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-18

2414 Insect hormone PTTH regulates lifespan through temporal and spatial activation of NF-κB signaling during metamorphosis

Kang, P.; Liu, P.; Kim, J.; Kumar, A.; Bolton, M.; Murzyn, W. A.; Anderson, Z. J.; Frank, L. N.; Kavlock, N.; Hoffman, E.; Martin, C. C.; Dorneich-Hayes, M. K.; Miao, T.; Shimell, M.; Chen, W.; Hu, Y.; Powell-Coffman, J.; O'Connor, M. B.; Perrimon, N.; Bai, H.

10.1101/2023.09.30.560323 — physiology — Posted on 2024-08-18

2415 Sulfoglycodendron Antivirals with Scalable Architectures and Activities

Coppola, F.; Jafari, R.; McReynolds, K. D.; KRAL, P.

10.1101/2024.08.01.606251 — pharmacology and toxicology — Posted on 2024-08-18

2416 Dissecting the transcriptional regulation of infant and childhood acute myeloid leukemia

Godini, R.

10.1101/2024.08.14.608016 — cancer biology — Posted on 2024-08-18

2417 Identification of druggable targets from the interactome of the Androgen Receptor and Serum Response Factor pathways in prostate cancer.

Azam, H.; Veale, C.; Zitzmann, K.; Marcone, S.; Gallagher, W. M.; Prencipe, M.

10.1101/2024.08.15.608046 — cancer biology — Posted on 2024-08-18

2418 Spiral-eyes: A soft active matter model of in vivo corneal epithelial cell migration

Kostanjevec, K.; Sknepnek, R.; Collinson, J. M.; Henkes, S.

10.1101/2024.08.14.608002 — biophysics — Posted on 2024-08-18

2419 A dynamic compositional equilibrium governs mRNA recognition by eIF3

Ide, N. A.; Gentry, R. C.; Rudbach, M. A.; Yoo, K.; Velez, P. K.; Communale, V. M.; Hartwick, E. W.; Kinz-Thompson, C. D.; Gonzalez, R. L.; Aitken, C. E.

10.1101/2024.04.25.581977 — biophysics — Posted on 2024-08-18

2420 Ligand-Mediated Endocytosis Is Regulated in a Sexually Dimorphic Way in Osteocytes in vivo

Matthews, M. D.; Saffari, A. W.; Mukul, N. A.; Hai, J.; Wiesner, U. B.; Lewis, K. J.

10.1101/2024.08.18.608500 — bioengineering — Posted on 2024-08-18

2421 Enhancing wheat yield potential through the QFFE.perg-5A and QFEm.perg-3A associated to spike fruiting efficiency: Insights from plot-level analysis

Pretini, N.; Vanzetti, L. S.; Terrile, I. I.; Silva, P. M.; Ferrari, G.; Gonzalez, F. G.

10.1101/2024.08.14.607938 — genetics — Posted on 2024-08-18

2422 Phyloepigenetics in phylogeny analyses

Santourlidis, S.

10.1101/2024.08.14.607911 — evolutionary biology — Posted on 2024-08-18

2423 Disease and ectoparasite management improve nestling golden eagle health and survival: An effective mitigation strategy

Heath, J. A.; Davis, C. M.; Dudek, B. M.; McClure, C. J. W.; Myers, K. T.; Regnier, E. K.; Rolek, B. W.; Santiago, A. L.

10.1101/2024.08.14.607861 — ecology — Posted on 2024-08-18

2424 Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF-Trap

Destan, E.; Turkut, E.; Aldeniz, A.; Kang, J.; Tosha, T.; Yabashi, M.; Yilmaz, B.; Timucin, A. C.; Matsuura, H.; Kawano, Y.; Cinkaya, I.; DeMirci, H.

10.1101/2024.08.18.608484 — molecular biology — Posted on 2024-08-18

2425 Dietary Bioactive Compounds Trigger Distinct Epigenetic and Metabolic Reprogramming in Lactobacillus acidophilus

Kong, Y.; Adejoro, D. O.; Wescombe, P. A.; Winefield, C.; On, S. L. W.; Mitchell, N. L.; Subbaraj, A.; Saunders, A.; Maes, E.; Chelikani, V.

10.1101/2024.08.18.608491 — microbiology — Posted on 2024-08-18

2426 Antibiotic-mediated microbial community restructuring is dictated by variability in antibiotic susceptibility and population interactions

Kim, K.; Weiss, A.; Ma, H. R.; Son, H.-I.; Zhou, Z.; You, L.

10.1101/2024.08.18.608515 — microbiology — Posted on 2024-08-18

2427 Opsin-based photoreception in Crinoids

Nonclercq, Y.; Lienard, M.; Lourtie, A.; Duthoo, E.; Vanespen, L.; Eeckhaut, I.; Flammang, P.; Delroisse, J.

10.1101/2024.08.14.607903 — zoology — Posted on 2024-08-18

2428 Growth rate-driven modelling reveals how phenotypic adaptation drives drug resistance in BRAFV600E-mutant melanoma

HAMIS, S.; Browning, A. P.; Jenner, A. L.; Villa, C.; Maini, P.; Cassidy, T.

10.1101/2024.08.14.607616 — cancer biology — Posted on 2024-08-18

2429 Finding the E-Channel Proton Loading Sites by Calculating the Ensemble of Protonation Microstates

Uddin, M. R.; Khaniya, U.; Gupta, C.; Mao, J.; Ranepura, G.; Wei, R.; Soto, J. O.; Singharoy, A.; Gunner, M.

10.1101/2024.08.14.608010 — biophysics — Posted on 2024-08-18

2430 High accuracy methylation identification tools on single molecular level for PacBio HiFi data

Chen, Y.; Wu, B.; Ding, Y.; Niu, L.; Bai, X.; Lin, Z.; Xiao, C.-L.

10.1101/2024.08.14.607879 — bioinformatics — Posted on 2024-08-18

2431 Inner membrane components of the plasmid pKM101 type IV secretion system TraE and TraD are DNA-binding proteins

Jemouai, Z.; Sverzhinsky, A.; Sygusch, J.; Pascal, J.; Baron, C.

10.1101/2024.08.18.608465 — biochemistry — Posted on 2024-08-18

2432 Kinetics of i-motif folding within the duplex context

Alieva, R.; Keshek, A.; Zatsepin, T.; Orlov, V.; Aralov, A.; Zavyalova, E.

10.1101/2024.08.18.608433 — biochemistry — Posted on 2024-08-18

2433 Benchmarking DNA Foundation Models for Genomic Sequence Classification

Feng, H.; Wu, L.; Zhao, B.; Huff, C.; Zhang, J.; Wu, J.; Lin, L.; Wei, P.; Wu, C.

10.1101/2024.08.16.608288 — genomics — Posted on 2024-08-18

2434 Genetic variations associated with adaptation processes in Acrocomia palms: A comparative study across the Neotropic for future crop improvement

Morales-Marroquin, J. A.; Diaz-Hernandez, B. G.; Vianna, S. A.; Alves-Pereira, A.; de Araujo-Batista, C. E.; Colombo, C. A.; Pinheiro, J. B.; Zucchi, M. I.

10.1101/2024.08.15.608149 — genomics — Posted on 2024-08-18

2435 FindingNemo: A Toolkit for DNA Extraction, Library Preparation and Purification for Ultra Long Nanopore Sequencing

Cahyani, I.; Tyson, J.; Holmes, N.; Quick, J.; Moore, C.; Loman, N. J.; Loose, M. W.

10.1101/2024.08.16.608306 — genomics — Posted on 2024-08-18

2436 Comparative Transcriptomes of Canine and Human Prostate Cancers Identify Mediators of Castration Resistance

Angel, M. R.; Seguin, B.; Lohr, C. V.; Beer, T.; Feliciano, J.; Ramsey, S. A.; Thomas, G. V.

10.1101/2024.08.18.608482 — genetics — Posted on 2024-08-18

2437 Direction and modality of transcription changes caused by TAD boundary disruption in Slc29a3/Unc5b locus depends on tissue-specific epigenetic context

Salnikov, P. A.; Belokopytova, P. S.; Yan, A. P.; Viesna, E.; Korablev, A. N.; Serova, I. A.; Lukyanchikova, V. A.; Stepanchuk, Y. K.; Torgunakov, N. Y.; Tikhomirov, S. A.; Fishman, V. S.

10.1101/2024.08.16.608309 — genetics — Posted on 2024-08-18

2438 Gut microbiota dysbiosis induced by brain tumor modulates the efficacy of immunotherapy

Kim, H. C.; Kim, H.-J.; La, J.; Park, W. H.; Park, S. H.; Kang, B. H.; Kim, Y.; Lee, H. K.

10.1101/2024.08.18.608488 — microbiology — Posted on 2024-08-18

2439 Chaparral wildfire shifts the functional potential for soil pyrogenic organic matter and nitrogen cycling

Pulido-Chavez, M. F.; Nelson, A. R.; Wilkins, M. R.; Glassman, S. I.

10.1101/2024.08.18.607989 — microbiology — Posted on 2024-08-18

2440 Genome-resolved diversity and biosynthetic potential of the coral reef microbiome

Paoli, L.; Wiederkehr, F.; Ruscheweyh, H.-J.; Miravet-Verde, S.; Bistolas, K. S. I.; Sawyer, T.; Labadie, K.; Mayer, K.-I.; Perdereau, A.; Reddy, M. M.; Moulin, C.; Boissin, E.; Bourdin, G.; Cailliau, J.; Iwankow, G.; Poulain, J.; Romac, S.; Tara Pacific Consortium Coordinators, ; Planes, S.; Allemand, D.; Agostini, S.; Bowler, C.; Douville, E.; Forcioli, D.; Galand, P. E.; Lombard, F.; Oliveira, P. H.; Piel, J.; Thomas, O.; Thurber, R. V.; Trouble, R.; Voolstra, C. R.; Wincker, P.; Ziegler, M.; Sunagawa, S.

10.1101/2024.08.18.608444 — microbiology — Posted on 2024-08-18

2441 Blastocoel expansion and AMOT degradation cooperatively promote YAP nuclear localization during epiblast formation

Maeda, H.; Sasaki, H.

10.1101/2024.08.15.608017 — developmental biology — Posted on 2024-08-18

2442 ETS TRANSCRIPTION FACTOR POINTED CONTROLS GERMLINE SURVIVAL IN DROSOPHILA

Rosales-Nieves, A. E.; Marin-Menguiano, M.; Lopez-Onieva, L.; Garrido-Maraver, J.; Gonzalez-Reyes, A.

10.1101/2024.08.15.608137 — developmental biology — Posted on 2024-08-18

2443 Fate specification triggers a positive feedback loop of TEAD-YAP and NANOG to promote epiblast formation in preimplantation embryos

Hirono, N.; Hashimoto, M.; Maeda, H.; Shimojo, H.; Sasaki, H.

10.1101/2024.08.15.608179 — developmental biology — Posted on 2024-08-18

2444 Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins

Thorwald, M. A.; Godoy-Lugo, J. A.; Santa Maria, N.; Chakhoyan, A.; O'Day, P.; Jacobs, R.; Zlokovic, B.; Finch, C.

10.1101/2024.08.14.607970 — neuroscience — Posted on 2024-08-18

2445 Rapid and accurate genotype imputation from low coverage short read, long read, and cell free DNA sequence

Li, Z.; Albrechtsen, A.; Davies, R. W.

10.1101/2024.07.18.604149 — bioinformatics — Posted on 2024-08-18

2446 Insomnia score: predictive ability of insomnia, high-diagnostic and prognostic value for cancer.

Zhou, C.; Lan, Y.; Zhang, H.; Li, S.; Liu, S.; Liu, Y.; Shao, H.

10.1101/2024.08.13.607749 — bioinformatics — Posted on 2024-08-18

2447 The requirement of GW182 in miRNA-mediated gene silencingin Drosophila larval development

Matsuura-Suzuki, E.; Kiyokawa, K.; Iwasaki, S.; Tomari, Y.

10.1101/2022.06.15.496358 — genetics — Posted on 2024-08-17

2448 FRET-sensitized acceptor emission localization (FRETsael) - nanometer localization of biomolecular interactions using fluorescence lifetime imaging

Razvag, Y.; Drori, P.; Klemfner, S.; Meshorer, E.; Lerner, E.

10.1101/2023.12.10.570984 — biophysics — Posted on 2024-08-18

2449 Deep learning models of RNA base-pairing structures generalize to unseen folds and make accurate zero-shot predictions of base-base interactions of RNA complexes

lang, m.; Litfin, T.; Chen, K.; Zhan, J.; Zhou, Y.

10.1101/2023.09.26.559463 — bioinformatics — Posted on 2024-08-18

2450 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress

Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.

10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-17

2451 The genetic architecture of cell-type-specific cis-regulation

Marand, A. P.; Jiang, L.; Gomez-Cano, F. A.; Minow, M. A. A.; Zhang, X.; Mendieta, J. P.; Luo, Z.; Bang, S.; Yan, H.; Meyer, C.; Schlegel, L.; Johannes, F.; Schmitz, R. J.

10.1101/2024.08.17.608383 — genetics — Posted on 2024-08-17

2452 Cyclic di-GMP as an Antitoxin Regulates Bacterial Genome Stability and Antibiotic Persistence in Biofilms

Liao, H.; Yan, X.; Wang, C.; Huang, C.; Zhang, W.; Xiao, L.; Jiang, J.; Bao, Y.; Huang, T.; Zhang, H.; Guo, C.; Zhang, Y.; Pu, Y.

10.1101/2024.05.22.595364 — microbiology — Posted on 2024-08-17

2453 Hedgehog signaling controls cytotoxic T cell migration in the tumour microenvironment.

Kapeni, C.; O'Brien, L.; Sabirova, D.; Cast, O.; Carbonaro, V.; Clark-Leonard, S.; Beke, F.; McDonald, S.; Fife, K.; de la Roche, M.

10.1101/2024.08.14.607917 — immunology — Posted on 2024-08-17

2454 Dynamic coding and sequential integration of multiple reward attributes by primate amygdala neurons

Grabenhorst, F.; Baez-Mendoza, R.

10.1101/2024.08.17.608391 — neuroscience — Posted on 2024-08-17

2455 A triple dissociation across the medial, ventral, and lateral orbitofrontal cortex in rats making sequential foraging decisions

Cunningham, P. J.; Redish, A. D.

10.1101/2024.08.17.608409 — neuroscience — Posted on 2024-08-17

2456 Next generation AMA1-based plasmids for enhanced heterologous expression in filamentous fungi

Roux, I.; Woodcraft, C.; Sbaraini, N.; Pepper, A.; Wong, E.; Bracegirdle, J.; Chooi, Y.-H.

10.1101/2024.06.01.596972 — synthetic biology — Posted on 2024-08-17

2457 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress

Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.

10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-17

2458 Identifying a gene signature of metastatic potential by linking pre-metastatic state to ultimate metastatic fate

Handler, J. S.; Li, Z.; Dveirin, R. K.; Fang, W.; Goodarzi, H.; Fertig, E. J.; Kalhor, R.

10.1101/2024.08.14.607813 — cancer biology — Posted on 2024-08-17

2459 Mechanical strain focusing at topological defect sites in regenerating Hydra

Maroudas-Sacks, Y.; Suganthan, S.; Garion, L.; Ascoli-Abbina, Y.; Westfried, A.; Dori, N.; Pasvinter, I.; Popovic, M.; Keren, K.

10.1101/2024.06.13.598802 — biophysics — Posted on 2024-08-17

2460 Anchor Point Engineering on Anticalin Scaffolds for Enhanced Particle Adhesion to CTLA-4 Under Shear Stress

Sun, Y.; Li, J.; Vanella, R.; Liu, H.; Liu, Z.; Nash, M.

10.1101/2024.08.16.608260 — biophysics — Posted on 2024-08-17

2461 VieMedKG: Knowledge Graph and Benchmark for Traditional Vietnamese Medicine

Trinh, T.; Dao, A.; Nhung, H. T. H.; Truong Son, H.

10.1101/2024.08.07.606195 — bioinformatics — Posted on 2024-08-17

2462 Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies

Ford, C. T.; Yasa, S.; Obeid, K.; Guirales-Medrano, S.; White, R. A.; Janies, D.

10.1101/2024.07.14.603367 — bioinformatics — Posted on 2024-08-17

2463 Phase Separation Clustering of Poly Ubiquitin Cargos on the Ternary Mixture Lipid Membranes by Synthetically Cross-Linked Ubiquitin Binder Peptides.

Kim, S.; Okafor, K. K.; Tabuchi, R.; Briones, C.; Lee, I.-H.

10.1101/2024.08.17.608403 — biochemistry — Posted on 2024-08-17

2464 Nernst Equilibrium, Rectification, and Saturation: Insights into Ion Channel Behavior

Carlsen, R.; Weckel-Dahman, H.; Swanson, J. M.

10.1101/2024.08.16.608320 — biochemistry — Posted on 2024-08-17

2465 Single-cell and spatial transcriptomics of vulvar lichen sclerosus reveal multicompartmental alterations in gene expression and signaling cross-talk

Sun, P.; Kraus, C. N.; Zhao, W.; Xu, J.; Suh, S.; Nguyen, Q.; Jia, Y.; Nair, A.; Oakes, M.; Tinoco, R.; Shiu, J.; Sun, B.; Elsensohn, A. N.; Atwood, S. X.; Nie, Q.; Dai, X.

10.1101/2024.08.14.607986 — genomics — Posted on 2024-08-17

2466 Analysis of 3.6 million individuals yields minimal evidence of pairwise genetic interactions for height

Jabalameli, M. R.; Holmes, M. V.; Hinds, D.; 23andMe Research Team, ; Auton, A.; Fontanillas, P.

10.1101/2024.08.15.608197 — genomics — Posted on 2024-08-17

2467 Enhancing transcriptome expression quantification through accurate assignment of long RNA sequencing reads with TranSigner

Ji, H. J.; Pertea, M.

10.1101/2024.04.13.589356 — genomics — Posted on 2024-08-17

2468 Delineating bacterial genera based on gene content analysis: a case study of the Mycoplasmatales-Entomoplasmatales clade within the class Mollicutes

Yan, X.-H.; Pei, S.-C.; Yen, H.-C.; Blanchard, A.; Sirand-Pugnet, P.; Baby, V.; Gasparich, G. E.; Kuo, C.-H.

10.1101/2024.08.17.608393 — genomics — Posted on 2024-08-17

2469 Diverse Genotype-by-Weather Interactions in Switchgrass

MacQueen, A. H.; Zhang, L.; Smith, S.; Bonette, J.; Boe, A. R.; Fay, P. A.; Fritschi, F. B.; Lowry, D. B.; Mitchell, R. B.; Rouquette, F. M.; Wu, Y.; Harpak, A.; Juenger, T. E.

10.1101/2021.08.19.456975 — genetics — Posted on 2024-08-17

2470 Valine restriction extends survival in a Drosophila model of short-chain enoyl-CoA hydratase 1 (ECHS1) deficiency

Mele, S.; Martelli, F.; Barlow, C.; Jefferies, G.; Dworkin, S.; Christodoulou, J.; Schittenhelm, R. B.; Piper, M. D.; Johnson, T. K.

10.1101/2024.08.15.608013 — genetics — Posted on 2024-08-17

2471 The MRE11-RAD50-NBS1 complex both starts and extends DNA end resection in mouse meiosis

Kim, S.; Yamada, S.; Li, T.; Canasto-Chibuque, C.; Kim, J. H.; Marcet-Ortega, M.; Xu, J.; Eng, D. Y.; Feeney, L.; Petrini, J. H. J.; Keeney, S.

10.1101/2024.08.17.608390 — genetics — Posted on 2024-08-17

2472 Genetic basis of resistance in hosts facing alternative infection strategies by a virulent bacterial pathogen

Mathieu-Begne, E.; Gattis, S.; Ebert, D.

10.1101/2024.08.15.607931 — evolutionary biology — Posted on 2024-08-17

2473 Shifts in vernalization and phenology at the rear edge hold insight into adaptation of temperate plants to future milder winters

Perrier, A.; Turner, M. C.; Galloway, L. F.

10.1101/2024.08.16.608089 — evolutionary biology — Posted on 2024-08-17

2474 Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

Langley, C. A.; Dietzen, P. A.; Emerman, M.; Tenthorey, J. L.; Malik, H. S.

10.1101/2024.08.06.606855 — evolutionary biology — Posted on 2024-08-17

2475 Transgenerational effects impact the vulnerability of a host-parasitoid system to rising temperatures.

Bright, N. L.; Chen, J.; Terry, C.

10.1101/2024.08.16.608228 — ecology — Posted on 2024-08-17

2476 Worldwide Soundscapes: a synthesis of passive acoustic monitoring across realms

Darras, K. F.; Rountree, R.; Van Wilgenburg, S.; Cord, A. F.; Chen, Y.; Dong, L.; Rocquencourt, A.; Desjonqueres, C.; Diaz, P. M.; Lin, T.-H.; Gasc, A.; Marley, S.; Salton, M.; Schille, L.; Wensveen, P. J.; Wu, S.-H.; Acevedo-Charry, O.; Adam, M.; Aguzzi, J.; Akoglu, I.; Amorim, M. C. P.; Andre, M.; Antonelli, A.; Aparecido Do Nascimento, L.; Appel, G.; Archer, S.; Astaras, C.; Atemasov, A.; Atkinson, J.; Attia, J.; Baltag, E.; Barbaro, L.; Basan, F.; Batist, C.; Baucells, A. L.; Baumgarten, J. E.; Bayle Sempere, J. T.; Bellisario, K.; Ben David, A.; Berger-Tal, O.; Betts, M. G.; Bhalla, I.; B

10.1101/2024.04.10.588860 — ecology — Posted on 2024-08-17

2477 Challenges in detecting ecological interactions using sedimentary ancient DNA data

Callahan, F. M.; Li, K.; Nielsen, R.

10.1101/2024.08.16.608343 — ecology — Posted on 2024-08-17

2478 RAD52 prevents accumulation of Polalpha-dependent replication gaps at perturbed replication forks in human cells

Di Biagi, L.; Marozzi, G.; Malacaria, E.; Honda, M.; Aiello, F. A.; Valenzisi, P.; Spies, M.; Franchitto, A.; Pichierri, P.

10.1101/2023.04.12.536536 — cell biology — Posted on 2024-08-17

2479 Neuromuscular dysfunction in patient-derived FUSR244RR-ALS iPSC model via axonal downregulation of neuromuscular junction proteins

von Kuegelgen, N.; Ludwik, K.; Mendonsa, S.; Roemer, C.; Becher, E.; Breimann, L.; Strauch, M.; Mari, T.; Mongellaz, S.; Grexa, N.; Oliveras-Martinez, A.; Woehler, A.; Selbach, M.; la Bella, V.; Ulitsky, I.; Chekulaeva, M.

10.1101/2024.08.17.607965 — cell biology — Posted on 2024-08-17

2480 Human Replication Protein A complex is a Telomerase Processivity Factor Essential for Telomere Maintenance

Agrawal, S.; Lin, X.; Susvirkar, V.; O'Connor, M. S.; Chavez, B. L.; Tholkes, V. R.; Abe, K. M.; He, Q.; Huang, X.; Lim, C. J.

10.1101/2024.08.16.608355 — molecular biology — Posted on 2024-08-17

2481 Protein Arginine Methylation of the Translation Initiation Factor eIF1A Increases Usage of a Near-cognate Start Codon

Wegman, R.; Langberg, M.; Davis, R. B.; Liu, X.; Luo, M.; Yu, M. C.; Walker, S. E.

10.1101/2024.08.16.608280 — molecular biology — Posted on 2024-08-17

2482 Clu1/Clu form mitochondria-associated granules upon metabolic transitions and regulate mitochondrial protein translation via ribosome interactions

Miller-Fleming, L.; Au, W. H.; Raik, L.; Rebelo-Guiomar, P.; Schmitz, J.; Cho, H. Y.; Czako, A.; Whitworth, A. J.

10.1101/2024.08.17.608283 — molecular biology — Posted on 2024-08-17

2483 CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs

Shorrock, H. K.; Aliyeva, A.; Frias, J. A.; DeMeo, V. A.; Lennon, C. D.; DeMeo, C. C.; Merritt, A. K.; Shaughnessy, S.; Mazdiyasni, H.; Cleary, J. D.; Reddy, K.; Vangaveti, S.; Shin, D. S.; Berglund, J. A.

10.1101/2024.08.17.608349 — molecular biology — Posted on 2024-08-17

2484 Field-evolved resistance to neonicotinoids in the mosquito, Anopheles gambiae, is associated with downregulation and mutations of nicotinic acetylcholine receptor subunits combined with cytochrome P450-mediated detoxification

Fouet, C.; Pinch, M. J.; Ashu, F. A.; Ambadiang, M. M.; Bouaka, C.; Bathronie, A. J.; Hernandez, C. A.; Rios, D. E.; Penlap-Beng, V.; Kamdem, C.

10.1101/2024.08.17.608399 — molecular biology — Posted on 2024-08-17

2485 A high-resolution view of RNA endonuclease cleavage in Bacillus subtilis

Taggart, J.; Dierksheide, J.; LeBlanc, H.; Lalanne, J.-B.; Durand, S.; Braun, F.; Condon, C.; Li, G.-W.

10.1101/2023.03.12.532304 — molecular biology — Posted on 2024-08-17

2486 Antiviral Library Screening Leads to Discovery of Novel and Potent Anticlostridial Compounds

Stolz, B. J.; Seleem, M. N.; Abouelkhair, A. A.

10.1101/2024.08.16.608359 — microbiology — Posted on 2024-08-17

2487 Improved Zika virus plaque assay using Vero/TMPRSS2 cell line

Oluwasemowo, O.; Graham, M.; Murugesh, D.; Borucki, M.

10.1101/2024.08.16.608323 — microbiology — Posted on 2024-08-17

2488 A rapid growth rate underpins the dominance of Hanseniaspora uvarum in spontaneous grape juice fermentations

Onetto, C. A.; McCarthy, J.; Schmidt, S.

10.1101/2024.08.16.608365 — microbiology — Posted on 2024-08-17

2489 Cross-linked agarose-gelatine beads as a substrate for investigating biofilms of bacterial pathogens

Roizman, D.; Herzog, M.; Nath, A.; Pachaimuthu, N.; Hujeirat, A.; Kuropka, B.; Rolff, J.; Rodriguez-Rojas, A.

10.1101/2024.08.16.608334 — microbiology — Posted on 2024-08-17

2490 Inhibition of glycolysis in tuberculosis-mediated metabolic rewiring reduces HIV-1 spread across macrophages

Vahlas, Z.; Faivre, N.; Monard, S.; Hertel, Q.; Maio, M.; Barros, J.; Lucas, A.; Phong, T.; Ben-Neji, M.; Corti, M.; Poincloux, R.; Blanchet, F.; Raynaud-Messina, B.; Letisse, F.; Neyrolles, O.; Lugo-Villarino, G.; Balboa, L.; Verollet, C.

10.1101/2024.08.14.607908 — immunology — Posted on 2024-08-17

2491 Monkey lateral prefrontal cortex subregions differentiate between perceptual exposure to visual stimuli

Leaman, K.; Yusif Rodriguez, N.; Ahuja, A.; Basu, D.; McKim, T. H.; Desrochers, T. M.

10.1101/2024.07.28.605513 — neuroscience — Posted on 2024-08-17

2492 Human-specific features of cerebellar astrocytes and Purkinje cells: an anatomical comparison with mice and macaques

Hercher, C.; Ellerbeck, K.; Toutee, L.; Ye, X.; Mpai, R.; Davoli, M. A.; Watt, A. J.; Murai, K. K.; Turecki, G.; Mechawar, N.

10.1101/2024.08.13.607849 — neuroscience — Posted on 2024-08-17

2493 Internal Neural Representations in Task-Switching Guided by Context Biases

Galella, S.; Ardid, S.

10.1101/2023.07.24.550365 — neuroscience — Posted on 2024-08-17

2494 Fast, scalable, and statistically robust cell extraction from large-scale neural calcium imaging datasets

Dinc, F.; Inan, H.; Hernandez, O.; Schmuckermair, C.; Hazon, O.; Tasci, T.; Ahanonu, B. O.; Zhang, Y.; Lecoq, J.; Haziza, S.; Wagner, M. J.; Erdogdu, M. A.; Schnitzer, M. J.

10.1101/2021.03.24.436279 — neuroscience — Posted on 2024-08-17

2495 Is subjective perceptual similarity metacognitive?

Moharramipour, A.; Zhou, W.; Rahnev, D.; Lau, H.

10.1101/2024.06.13.598769 — neuroscience — Posted on 2024-08-17

2496 Triggering and modulation of a complex behavior by a single peptidergic command neuron in Drosophila

Fernandez-Acosta, M.; Zanini, R.; Heredia, F.; Volonte, Y.; Menezes, J.; Pruger, K.; Ibarra, J.; Arana, M.; Perez, M. S.; Veenstra, J. A.; Wegener, C.; Gontijo, A. M.; Garelli, A.

10.1101/2024.04.27.591209 — neuroscience — Posted on 2024-08-17

2497 C9orf72 repeat expansion-carrying iPSC-microglia from FTD patients show increased phagocytic activity concomitantly with decreased number of autophagosomal-lysosomal vesicles

Rostalski, H.; Hietanen, T.; Hoffmann, D.; Heikkinen, S.; Huber, N.; Dhingra, A.; Rodriguez-Nieto, S.; Kuulasmaa, T.; Ohtonen, S.; Jantti, H.; Pekkala, V.; Leskela, S.; Makinen, P.; Katisko, K.; Hartikainen, P.; Lehtonen, S.; Solje, E.; Koistinaho, J.; Malm, T.; Portaankorva, A. M.; Natunen, T.; Martiskainen, H.; Takalo, M.; Hiltunen, M.; Haapasalo, A.

10.1101/2024.08.14.607573 — neuroscience — Posted on 2024-08-17

2498 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia

Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.

10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-17

2499 A nanobody-based proximity ligation assay detects constitutive and stimulus-regulated native Arc/Arg3.1 oligomers in hippocampal neuronal dendrites

Baldinotti, R.; Pauzin, F. P.; Fevang, H.; Ishizuka, Y.; Bramham, C. R.

10.1101/2024.08.14.607905 — neuroscience — Posted on 2024-08-17

2500 Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide SBT-20 in the D2.mdx model of Duchenne muscular dystrophy

Perry, C. G. R.; Hughes, M. C.; Ramos, S. V.; Brahmbhatt, A.; Turnbull, P. C.; Polidovitch, N.; Garibotti, M. C.; Schlattner, U.; Hawke, T. J.; Simpson, J. A.; Backx, P. H.

10.1101/2024.02.04.578832 — physiology — Posted on 2024-08-17

2501 Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers' effect on signaling and internalization

Zhou, P.; Tsunoyama, T. A.; Kasai, R. S.; Hirosawa, K. M.; Kalay, Z.; Aladag, A.; Fujiwara, T.; Pigolotti, S.; Kusumi, A.

10.1101/2024.07.25.605080 — biophysics — Posted on 2024-08-17

2502 hnRNPA1 RGG-box acts a "catalyst" in UP1-induced destabilization of RNA and DNA telomeric G-Quadruplexes

Balasubramanian, S.; Roy, I.; Appadurai, R.; Srivastava, A.

10.1101/2023.08.21.554222 — biophysics — Posted on 2024-08-17

2503 Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance

Zhou, P.; Kasai, R. S.; Fujita, W.; Tsunoyama, T. A.; Ueda, H.; Pigolotti, S.; Fujiwara, T.; Kusumi, A.

10.1101/2024.07.25.605109 — biophysics — Posted on 2024-08-17

2504 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia

Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.

10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-17

2505 Monsoonal climate and asymmetric heating facilitate the slope-aspect to influence landscape-scale tree structure in the Western Ghats, India

Maheshwori, D.; Managave, S.; Jathar, G.; Davande, S.

10.1101/2024.08.13.607866 — ecology — Posted on 2024-08-17

2506 The evolution of signalling and eavesdropping in plant-fungal networks

Scott, T. W.; Kiers, E. T.; West, S. A.

10.1101/2024.08.15.608109 — evolutionary biology — Posted on 2024-08-17

2507 Integrative genomics approach identifies glial transcriptomic dysregulation and risk in the cortex of individuals with Alcohol Use Disorder

Warden, A. S.; Salem, N. A.; Brenner, E.; Sutherland, G. T.; Stevens, J.; Kapoor, M.; Goate, A. M.; Mayfield, R. D.

10.1101/2024.08.16.607185 — neuroscience — Posted on 2024-08-17

2508 Phosphoryl group wires stabilize pathological tau fibrils as revealed by multiple quantum spin counting NMR

Potnuru, L. R.; DuBose, A.; Nowotarski, M. S.; Vigers, M.; Zhang, B.; Han, C.-T.; Han, S.

10.1101/2024.08.14.606685 — biophysics — Posted on 2024-08-17

2509 One pot RNA:DNA assembly for ribosomal RNA detection of pathogenic bacteria with single-molecule sensitivity

Boskovic, F. N.; Sandler, S.; Brauburger, S.; Shui, Y.; Kumar, B.; Pereira Dias, J.; Naydenova, P.; Zhu, J.; Baker, S.; Keyser, U. F.

10.1101/2024.08.15.608086 — biophysics — Posted on 2024-08-17

2510 Molecular simulations of enzymatic phosphorylation of disordered proteins and their condensates

Zippo, E.; Dormann, D.; Speck, T.; Stelzl, L.

10.1101/2024.08.15.607948 — biophysics — Posted on 2024-08-17

2511 Myosin forces elicit an F-actin structural landscape that mediates mechanosensitive protein recognition

Carl, A. G.; Reynolds, M. J.; Gurel, P. S.; Phua, D. Y.; Sun, X.; Mei, L.; Hamilton, K.; Takagi, Y.; Noble, A. J.; Sellers, J. R.; Alushin, G. M.

10.1101/2024.08.15.608188 — biophysics — Posted on 2024-08-17

2512 Multipartite complexity of the lichen symbiosis revealed by metagenome and transcriptome analysis of Xanthoria parietina

Tagirdzhanova, G.; Scharnagl, K.; Sahu, N.; Yan, X.; Bucknell, A.; Bentham, A. R.; Jegousse, C.; Ament-Velasquez, S. L.; Brännström, I. O.; Johannesson, H.; MacLean, D.; Talbot, N. J.

10.1101/2024.08.16.608140 — bioinformatics — Posted on 2024-08-17

2513 Steering cell-state and phenotype transitions by causal disentanglement learning

Zhang, C.; Chen, Z.; Miao, Y.; Xue, Y.; Cai, D.; Guo, W.; Ji, h.; Aihara, K.; Chen, L.

10.1101/2024.08.16.607277 — bioinformatics — Posted on 2024-08-17

2514 Autoencoders with shared and specific embeddings formulti-omics data integration

Wang, C.; O'Connell, M. J.

10.1101/2024.08.14.607979 — bioinformatics — Posted on 2024-08-17

2515 Unlocking Protein Evolution Insights: Efficient and Interpretable Mutational Effect Predictions with GEMME

Carbone, A.; Laine, E.; Lombardi, G.

10.1101/2024.08.15.608048 — bioinformatics — Posted on 2024-08-17

2516 Conservative taxonomy and quality assessment of giant virus genomes with GVClass

Pitot, T. M.; Bruna, T.; Schulz, F.

10.1101/2024.08.15.607234 — bioinformatics — Posted on 2024-08-17

2517 Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins

Njenga, R.; Boele, J.; Drepper, F.; Sinha, K.; Marouda, E.; Huesgen, P. F.; Blaby-Haas, C.; Koch, H.-G.

10.1101/2024.08.16.608256 — biochemistry — Posted on 2024-08-17

2518 Interspecies differences in the transcriptome response of corals to acute heat stress

Da-Anoy, J.; Posadas, N.; Conaco, C.

10.1101/2024.08.16.607823 — genomics — Posted on 2024-08-17

2519 Comparison of Fixed Single Cell RNA-seq Methods to Enable Transcriptome Profiling of Neutrophils in Clinical Samples

Hatje, K.; Schneider, K.; Danilin, S.; Koechl, F.; Giroud, N.; Juglair, L.; Marbach, D.; Knuckles, P.; Bergauer, T.; Metruccio, M.; Garrido, A.; Zhang, J. D.; Sultan, M.; Bell, E.

10.1101/2024.08.14.607767 — genomics — Posted on 2024-08-17

2520 Shifts in vernalization and phenology at the rear edge hold insight into adaptation of 1 temperate plants to future milder winters

Perrier, A.; Turner, M. C.; Galloway, L. F.

10.1101/2024.08.16.608089 — evolutionary biology — Posted on 2024-08-17

2521 Excluding Large Grazers Dramatically Improves Survival of Outplanted Juvenile Corals

van der Steeg, E.; Humanes, A.; Bythell, J. C.; Craggs, J. R.; Edwards, A. J.; Golbuu, Y.; Lachs, L.; Miller, M. W.; Randle, J. L.; Guest, J. R.

10.1101/2024.08.15.607490 — ecology — Posted on 2024-08-17

2522 Formation of giant ER sheets by pentadecanoic acid causes lipotoxicity in fission yeast

Hoshikawa, Y.; Shirota, N.; Tsugawa, H.; Kimura, S.; Matsuyama, A.; Yashiroda, Y.; Kakeya, H.; Arita, M.; Iizumi, R.; Yoshida, M.; Nishimura, S.

10.1101/2024.08.15.608187 — cell biology — Posted on 2024-08-17

2523 Coral microbiomes from the Atlantic and Indo-Pacific oceans have the same alpha diversity but different composition

Santos, M. E. A.; Reimer, J. D.; Kiriukhin, B.; Wee, H. B.; Mizuyama, M.; Kise, H.; Kitahara, M. V.; Iguchi, A.; Dudoit, A.; Toonen, R. J.; Husnik, F.

10.1101/2024.08.16.608269 — microbiology — Posted on 2024-08-17

2524 A Single Mutation in an Enteric Virus Alters Tropism and Sensitivity to Microbiota

Erickson, A. K.; Sutherland, D. M.; Welch, O. L.; Maples, R. W.; Dermody, T. S.; Pfeiffer, J. K.

10.1101/2024.08.16.608258 — microbiology — Posted on 2024-08-17

2525 A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion

Yu, M.; Lin, A.; Baharom, F.; Li, S.; Legendre, M.; Coves-Datson, E.; Sohlberg, E.; Schlisio, S.; Lore, K.; Markovitz, D. M.; Smed-Sorensen, A.

10.1101/2024.08.15.608041 — immunology — Posted on 2024-08-17

2526 Electrical Synapse Rectification Enables Dual-Network Activity in the crab Cancer borealis

Fahoum, S.-R. H.; Nadim, F.; Blitz, D. M.

10.1101/2024.08.15.608183 — neuroscience — Posted on 2024-08-17

2527 Overcoming off-target optical stimulation-evoked cortical activity in the mouse brain in vivo

Weiler, S.; Velez-Fort, M.; Margrie, T. W.

10.1101/2024.08.14.607152 — neuroscience — Posted on 2024-08-17

2528 The genetic landscape of antibiotic sensitivity in Staphylococcus aureus

Li, W.; Liu, M.; Oikonomou, P.; Blattman, S. B.; Hettleman, J.; Gonzalez, J.; Chen, H.; Tavazoie, S.; Jiang, W.

10.1101/2024.08.15.608136 — systems biology — Posted on 2024-08-17

2529 Removal of NHS-labelling by-products in Proteomic Samples

Demyanenko, Y.; Giltrap, A. M.; Davis, B. G.; Mohammed, S.

10.1101/2024.08.15.607975 — systems biology — Posted on 2024-08-17

2530 A Novel Computational Machine Learning Pipeline to Quantify Similarities in Three-Dimensional Protein Structures

Hirway, S. U.; Xu, X.; Fan, F.

10.1101/2024.08.14.607969 — pharmacology and toxicology — Posted on 2024-08-17

2531 Genome Instability Precedes Viral Integration in Human Papilloma Virus Transformed Tonsillar Keratinocytes

Chan, K.; Tseng, C.; Malarachi, E.; Goldrich, D.; Schneper, L.; Sheldon, K.; Alam, S.; Aliaga, C.; Chatterjee, S.; El-Bayoumy, K.; Meyers, C.; Goldenberg, D.; Broach, J. R.

10.1101/2024.08.14.607944 — cancer biology — Posted on 2024-08-17

2532 AVJ16 inhibits the RNA binding protein IGF2BP1 in lung adenocarcinomas and prevents tumor growth in mice

Wallis, N.; Gershon, T.; Shaaby, S.; Oberman, F.; Grunewald, M.; Duran, D.; Singh, A.; Vainer, G.; Spiegelman, V. S.; Sharma, A. K.; Yisraeli, J. K.

10.1101/2024.08.15.608038 — cancer biology — Posted on 2024-08-17

2533 A range of voltage-clamp protocol designs for rapid capture of hERG kinetics

Lei, C. L.; Whittaker, D. G.; Windley, M. J.; Perry, M. D.; Hill, A. P.; Mirams, G. R.

10.1101/2024.08.14.607756 — biophysics — Posted on 2024-08-17

2534 Sidelobe suppressed Bessel beams for one-photon light-sheet microscopy

Taneja, C.; George, J. G.; Corsetti, S.; Wijesinghe, P.; Bruce, G. D.; Zwart, M. F.; Bhattacharya, S.; Dholakia, K.

10.1101/2024.08.15.607323 — biophysics — Posted on 2024-08-17

2535 PhyClone: Accurate Bayesian reconstruction of cancer phylogenies from bulk sequencing

Hurtado, E.; Bouchard-Cote, A.; Roth, A.

10.1101/2024.08.14.607069 — bioinformatics — Posted on 2024-08-17

2536 GENOMICON-Seq: A comprehensive tool for the simulation of mutations in amplicon and whole exome sequencing

Stosic, M. S.; Costanzi, J.-M.; Ambur, O. H.; Rounge, T. B.

10.1101/2024.08.14.607907 — bioinformatics — Posted on 2024-08-17

2537 DeepSME: De Novo Nanopore Basecalling of Motif-insensitive DNA Methylation and Alignment-free Digital Information Decryptions at Single-Molecule Level

Fan, Q.; Zhao, X.; Li, J.; Liu, R.; Liu, M.; Long, Y.; Fu, Y.; Feng, Q.; Zhai, J.; Pan, Q.; Li, Y.

10.1101/2024.08.15.606762 — bioinformatics — Posted on 2024-08-17

2538 Large protein databases reveal structural complementarity and functional locality

Szczerbiak, P.; Szydlowski, L.; Wydmanski, W.; Renfrew, P. D.; Koehler Leman, J.; Kosciolek, T.

10.1101/2024.08.14.607935 — bioinformatics — Posted on 2024-08-17

2539 Prediction of Oligomeric Status of Quaternary Protein Structure by using Sequential Minimal Optimization for Support Vector Machine

Kumar, S.

10.1101/2024.08.15.608027 — bioinformatics — Posted on 2024-08-17

2540 CHAMP delivers accurate taxonomic profiles of the prokaryotes, eukaryotes, and bacteriophages in the human microbiome

Pita, S.; Myers, P. N.; Johansen, J.; Russel, J.; Nielsen, M. C.; Eklund, A. C.; Nielsen, H. B.

10.1101/2024.08.15.608036 — bioinformatics — Posted on 2024-08-17

2541 Optogenetic quantification of source sink relationship in intact hearts to explain cardiac arrhythmia initiation and protection

Langen, J. S.; Boyle, P. M.; Malan, D.; Sasse, P.

10.1101/2024.08.14.604123 — bioengineering — Posted on 2024-08-17

2542 Origins of de novo chromosome rearrangements unveiled by coupled imaging and genomics

Cosenza, M. R.; Gaiatto, A.; Erarslan Uysal, B.; Andrades Delgado, A.; Sautter, N. L.; Jendrusch, M. A.; Zumalave Duro, S.; Rausch, T.; Halavatyi, A.; Geissen, E.-M.; Hasenfeld, P.; Cortes-Ciriano, I.; Kulozik, A.; Pepperkok, R.; Korbel, J. O.

10.1101/2024.08.15.607890 — genomics — Posted on 2024-08-17

2543 WheresWalker: a pipeline for rapid mutation mapping using whole genome sequencing

Feltes, M.; Zimin, A. V.; Angel, S.; Pansari, N.; Hensley, M. R.; Anderson, J. L.; Shen, M.-C.; Klemek, M.; Shen, Y.; Ginde, V. S.; Truong, V. P.; Kozan, H.; Le, N. V.; Wilson, M. H.; Salzberg, S. L.; Farber, S. A.

10.1101/2024.08.14.607950 — genetics — Posted on 2024-08-17

2544 Ground nesting of soft eggs by extinct birds and a new parity mode switch hypothesis for the evolution of animal reproduction

Guimaraes, M. J.; Wang, J.; Zhang, X.; Sun, Q.; Cerqueira, M. F.; Chung, Y.-H.; Deng, R.; Guo, B.; Alpuim, P.; Ma, F.; Wang, X.; Yen, T.-C.

10.1101/2024.08.15.607182 — evolutionary biology — Posted on 2024-08-17

2545 Differences in energy storage in sympatric salmonid morphs with contrasting lifestyles

Esin, E. V.; N. Markevich, G. N.; Shulgina, E. V.; Baskakova, Y. A.; Atemov, R. V.; Shkil, F. N.

10.1101/2024.08.14.607877 — evolutionary biology — Posted on 2024-08-17

2546 The evolution of male weapons is associated with the type of breeding site in a clade of Neotropical frogs

Santana, E. M.; Caetano, D. S.; Palaoro, A. V.; Machado, G.

10.1101/2024.08.15.608145 — evolutionary biology — Posted on 2024-08-17

2547 Tryptophanase disruption underlies the evolution of insect-bacterium mutualism

Wang, Y.; Moriyama, M.; Koga, R.; Oguchi, K.; Hosokawa, T.; Takai, H.; Shigenobu, S.; Nikoh, N.; Fukatsu, T.

10.1101/2024.08.16.608268 — evolutionary biology — Posted on 2024-08-17

2548 Phenotypic divergence associated with genomic changes suggest local adaptation in obligate asexuals

Karapli-Petritsopoulou, A.; Heckelmann, J. J.; Anderson, N. J.; Franzenburg, S.; Frisch, D.

10.1101/2024.08.15.608098 — evolutionary biology — Posted on 2024-08-17

2549 Kin-discriminating partner choice promotes the evolution of helping

Scott, T. W.; Wild, G.; Gardner, A.

10.1101/2024.08.15.608103 — evolutionary biology — Posted on 2024-08-17

2550 Phylogenetic analysis of Centralspindlin and Ect2 provides mechanistic insights into the emergence of Metazoa and multicellularity

Glotzer, M.

10.1101/2024.08.16.607330 — evolutionary biology — Posted on 2024-08-17

2551 The level of HAND1 controls the specification of multipotent cardiac and extraembryonic progenitors

Lynch, A. T.; Phillips, N.; Douglas, M.; Dorgnach, M.; Lin, I.-H.; Adamson, A. D.; Darieva, Z.; Whittle, J.; Hanley, N. A.; Bobola, N.; Birket, M. J.

10.1101/2024.08.15.607916 — developmental biology — Posted on 2024-08-17

2552 The Changing Immune Landscape of Innate-like T Cells and Innate Cells Throughout Life

Taheri, M.; Menne, C.; Anderson, J.; Li, S.; Berzins, S. P.; Licciardi, P. V.; Ashhurst, T. M.; Jalali, S.; Pellicci, D. G.

10.1101/2024.08.14.608020 — immunology — Posted on 2024-08-17

2553 Quantitative 3D histochemistry reveals region-specific amyloid-β reduction by the antidiabetic drug netoglitazone

Catto, F.; Dadgar-Kiani, E.; Kirschenbaum, D.; Economides, A. E.; Reuss, A. M.; Trevisan, C.; Caredio, D.; Mirzet, D.; Frick, L.; Weber-Stadlbauer, U.; Litvinov, S.; Koumoutsakos, P.; Hyung Lee, J.; Aguzzi, A.

10.1101/2024.08.15.608042 — neuroscience — Posted on 2024-08-17

2554 The OMG dataset: An Open MetaGenomic corpus for mixed-modality genomic language modeling

Cornman, A.; West-Roberts, J.; Camargo, A. P.; Roux, S.; Beracochea, M.; Mirdita, M.; Ovchinnikov, S.; Hwang, Y.

10.1101/2024.08.14.607850 — systems biology — Posted on 2024-08-17

2555 Protein overabundance is driven by growth robustness

Choi, H. K.; Lo, T. W.; Cutler, K. J.; Huang, D.; Will, W. R.; Wiggins, P. A.

10.1101/2024.08.14.607847 — systems biology — Posted on 2024-08-17

2556 Convergent relaxation of molecular constraint in mammalian herbivores highlights the roles of liver and kidney functions in carnivory

Pollard, M. D.; Meyer, W. K.; Puckett, E. E.

10.1101/2023.11.17.567625 — genomics — Posted on 2024-08-17

2557 Heat Shock Factor 1 forms nuclear condensates and restructures the yeast genome before activating target genes

Rubio, L. S.; Mohajan, S.; Gross, D. S.

10.1101/2023.09.28.560064 — genetics — Posted on 2024-08-17

2558 Loss of cped1 does not affect bone and lean mass in zebrafish

Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.

10.1101/2024.07.10.601974 — genetics — Posted on 2024-08-17

2559 A Sox2 Enhancer Cluster Regulates Region-Specific Neural Fates from Mouse Embryonic Stem Cells

Tobias, I. C.; Moorthy, S. D.; Shchuka, V. M.; Langroudi, L.; Cherednychenko, M.; Gillespie, Z. E.; Duncan, A. G.; Tian, R.; Gajewska, N. A.; Di Roberto, R. B.; Mitchell, J. A.

10.1101/2023.11.09.566464 — genetics — Posted on 2024-08-17

2560 Tree sequences as a general-purpose tool for population genetic inference

Whitehouse, L. S.; Ray, D. D.; Schrider, D. R.

10.1101/2024.02.20.581288 — evolutionary biology — Posted on 2024-08-17

2561 Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females

Shain, A.; Savko, C.; Rokaw, S.; Jaafar, F.; Rieder, A.; Wright, M. K.; Phillips, J. A.; Konja, N.; Michael, S.; Mathews, H.; Jerjees, G.; Bailey, B.; Sussman, M.

10.1101/2024.08.01.606074 — molecular biology — Posted on 2024-08-17

2562 Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages

Winnicki, A. C.; King, C. L.; Bosch, J.; Malachin, A. N.; Carias, L. L.; Skomorovska-Prokvolit, Y.; Tham, W.-H.; Dietrich, M. H.; Popovici, J.; Roobsoong, W.; Beeson, J. G.; Sattabongkot, J.; Yeoh, L. M.; Opi, D. H.; Feufack-Donfack, L. B.; Orban, A.; Drago, C. L.; McLaine, O. S.; Redinger, K. R.; Jung, N. C.; Baldor, L.; Kirtley, P.; Neilsen, K.; Aleshnick, M.; Zanghi, G.; Rezakhani, N.; Vaughan, A. M.; Wilder, B. K.

10.1101/2024.02.07.579302 — immunology — Posted on 2024-08-17

2563 Novel tau filament folds in individuals with MAPT mutations P301L and P301T

Schweighauser, M.; Shi, Y.; Murzin, A. G.; Garringer, H. J.; Vidal, R.; Murrell, J. R.; Erro, M. E.; Seelaar, H.; Ferrer, I.; van Swieten, J. C.; Ghetti, B.; Scheres, S. H.; Goedert, M.

10.1101/2024.08.15.608062 — neuroscience — Posted on 2024-08-17

2564 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making

Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.

10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-08-17

2565 Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct.

de Guglielmo, G.; Carrette, L.; Kallupi, M.; Brennan, M.; Boomhower, B.; Maturin, L.; Conlisk, D.; Sedighim, S.; Tieu, L.; Fannon, M.; Martinez, A. R.; Velarde, N.; Othman, D.; Sichel, B.; Ramboger, J.; Lau, J.; Kononoff, J.; Kimbrough, A.; Simpson, S.; Smith, L.; Shankar, K.; Sneddon, E. A.; Bonnet-Zahedi, S.; Avelar, A.; Plasil, S. L.; Mosquera, J.; Crook, C.; Chun, L.; Vang, A.; Milan, K.; Schweitzer, P.; Lin, B.; Peng, B.; Chitre, A.; Polleskaya, O.; Woods, L. S.; Palmer, A. A.; George, O.

10.1101/2021.07.22.453410 — neuroscience — Posted on 2024-08-17

2566 Multimodal neural correlates of childhood psychopathology

Royer, J.; Kebets, V.; Piguet, C.; Chen, J.; Ooi, L. Q. R.; Kirschner, M.; Siffredi, V.; Misic, B.; Yeo, B. T. T.; Bernhardt, B.

10.1101/2023.03.02.530821 — neuroscience — Posted on 2024-08-17

2567 The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer

Souto, E. P.; Gong, P.; Landua, J. D.; Srinivasan, R. R.; Ganesan, A.; Dobrolecki, L. E.; Purdy, S. C.; Pan, X.; Zeosky, M.; Chung, A.; Yi, S. S.; Ford, H. L.; Lewis, M. T.

10.1101/2023.09.15.557958 — cancer biology — Posted on 2024-08-17

2568 Examining dynamics of three-dimensional genome organization with multi-task matrix factorization

Lee, D.-I.; Roy, S.

10.1101/2023.08.25.554883 — bioinformatics — Posted on 2024-08-17

2569 Functional investigation of a putative calcium-binding site involved in the inhibition of inositol 1,4,5-trisphosphate receptor activity

Arige, V.; Wagner, L. E.; Malik, S.; Baker, M. R.; Fan, G.; Serysheva, I. I.; Yule, D. I.

10.1101/2024.08.16.608318 — biochemistry — Posted on 2024-08-17

2570 GTP hydrolysis triggers membrane remodeling by AMPH-1

Gai, W.; Wang, Y.; Zhang, J.; Carr, C.; Rye, H.

10.1101/2024.08.16.608333 — biochemistry — Posted on 2024-08-17

2571 The kinetoplastid kinetochore protein KKT23 acetyltransferase is a structural homolog of GCN5 that acetylates the histone H2A C-terminal tail

Ludzia, P.; Ishii, M.; Deak, G.; Spanos, C.; Wilson, M. D.; Redfield, C.; Akiyoshi, B.

10.1101/2024.08.16.608276 — cell biology — Posted on 2024-08-17

2572 A spatial atlas of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress

Begeman, A.; Smolka, J. A.; Shami, A.; Waingankar, T. P.; Lewis, S. C.

10.1101/2024.08.05.604215 — cell biology — Posted on 2024-08-17

2573 Coupling of saccade plans to endogenous attention during urgent choices

Goldstein, A. T.; Stanford, T. R.; Salinas, E.

10.1101/2024.03.01.583058 — neuroscience — Posted on 2024-08-17

2574 REverse transcriptase ACTivity (REACT) assay for point-of-care measurement of established and emerging antiretrovirals for HIV treatment and prevention

Brainerd, C.; Singh, M. A.; Tatka, J.; Craig, C.; Gilligan-Steinberg, S.; Panpradist, N.; Chang, M. M.; Lutz, B.; Olanrewaju, A. O.

10.1101/2024.08.13.607804 — bioengineering — Posted on 2024-08-17

2575 Relationships of hematocrit concentration with dementia from a multiethnic population-based study

Roh, D. J.; Liu, M.; Strobino, K.; Assuras, S.; Guzman, V. A.; Levin, B.; Spitalnik, S.; Rundek, T.; Wright, C. B.; Elkind, M. S. V.; Gutierrez, J.

10.1101/2024.08.15.608190 — neuroscience — Posted on 2024-08-17

2576 Toss GERALT into chloroplast to make it green: a new regulator of chloroplast biogenesis and chlorophyll biosynthesis

10.1101/2024.08.16.608208 — plant biology — Posted on 2024-08-17

2577 Early atrial remodelling drives arrhythmia in Fabry Disease

Roy, A.; O'Shea, C.; Dasi, A.; Patel, L.; CUMBERLAND, M.; NIEVES, D.; Canagarajah, H. S.; THOMPSON, S.; AZAD, A.; Price, A. M.; HALL, C.; Alvior, A. M. B.; RATH, P.; DAVIES, B.; Rodriguez, B.; Holmes, A. P.; Pavlovic, D.; Townend, J. N.; Geberhiwot, T.; GEHMLICH, K.; Steeds, R. P.

10.1101/2024.08.13.607853 — pathology — Posted on 2024-08-17

2578 Single-cell imaging of the lytic phage life cycle in bacteria

Wedd, C.; Yunusov, T.; Smith, A.; Li, R.; Hardo, G.; Hunter, M.; Majed, R.; Fusco, D.; Bakshi, S.

10.1101/2024.04.11.588870 — microbiology — Posted on 2024-08-17

2579 PRR adjuvants restrain high stability peptides presentation on APCs

Li, B.; Zhang, J.; He, T.; Yuan, H.; Wu, H.; Wang, P.; Wu, C.

10.1101/2024.05.20.594923 — immunology — Posted on 2024-08-17

2580 Recovery of Verbal Working Memory Depends on Left Hemisphere White Matter Tracts

Martin, R. C.; Ding, J.; Alwani, A. I.; Fung, S. H.; Schnur, T. T.

10.1101/2024.08.16.608246 — neuroscience — Posted on 2024-08-17

2581 KS-WNK1 amplifies kidney tubule responsiveness to potassium via WNK body condensates

Boyd-Shiwarski, C. R.; Beacham, R. T.; Lashway, J. A.; Querry, K. E.; Griffiths, S. E.; Shiwarski, D. J.; Knoell, S. A.; Nguyen, N. H.; Nkashama, L. J.; Valladares, M. N.; Bandaru, A.; Marciszyn, A. L.; Rodan, A. R.; Huang, C.-L.; Stocker, S. D.; Kashlan, O. B.; Subramanya, A. R.

10.1101/2021.03.12.435046 — physiology — Posted on 2024-08-17

2582 The Lactate Receptor GPR81 is a Mechanism of Leukemia-Associated Macrophage Polarization in the Bone Marrow Microenvironment

Soto, C. A.; Lesch, M. L.; Becker, J. L.; Sharipol, A.; Khan, A.; Shafer, X. L.; Becker, M. W.; Munger, J. C.; Frisch, B. J.

10.1101/2023.11.13.566874 — pathology — Posted on 2024-08-17

2583 Flynotyper 2.0: An updated tool for rapid quantitative assessment of Drosophila eye phenotypes

Ray, J.; Banerjee, D.; Wang, Q.; Girirajan, S.

10.1101/2024.04.07.588481 — bioinformatics — Posted on 2024-08-16

2584 Differential structural organization and gene expression regulatory networks of lamin A Ig fold domain mutants of muscular dystrophy.

Dutta, S.; Kumar, V.; Vasudevan, M.; Barua, A.

10.1101/2022.05.30.493956 — biochemistry — Posted on 2024-08-17

2585 Dissociable patterns of dopamine dynamics and causal contributions to stimulus-response behaviors across striatal subregions.

Princz-Lebel, O.; Skirzewski, M.; Rai, H.; Panjwani, S.; Chu, A.; Lemieux, C. A.; Palmer, D.; Machado, M. M. F.; Prado, V. F.; Prado, M. A. M.; Saksida, L. M.; Bussey, T. J.

10.1101/2024.08.16.608313 — animal behavior and cognition — Posted on 2024-08-17

2586 Analysis of 3.6 million individuals yields minimal evidence of pairwise genetic interactions for height

Jabalameli, M.; Holmes, M. V.; 23andMe Research Team, ; Auton, A.; Fontanillas, P.

10.1101/2024.08.15.608197 — genomics — Posted on 2024-08-17

2587 Repeated shifts in sociality are associated with fine-tuning of highly conserved and lineage-specific enhancers in a socially flexible bee

Jones, B. M.; Webb, A. E.; Geib, S. M.; Sim, S.; Schweizer, R. M.; Branstetter, M. G.; Evans, J. D.; Kocher, S. D.

10.1101/2024.08.15.608154 — evolutionary biology — Posted on 2024-08-16

2588 Negative regulation of APC/C activation by MAPK-mediated attenuation of Cdc20Slp1 under stress

Sun, L.; Chen, X.; Song, C.; Shi, W.; Liu, L.; Bai, S.; Wang, X.; Chen, J.; Jiang, C.; Wang, S.-m.; Luo, Z.-q.; Wang, R.; Wang, Y.; Jin, Q.-w.

10.1101/2024.04.02.587770 — cell biology — Posted on 2024-08-17

2589 Surface exclusion of IncC conjugative plasmids and their relatives

Rivard, N.; Humbert, M.; Huguet, K. T.; Fauconnier, A.; Perez Bucio, C.; Quirion, E.; Burrus, V.

10.1101/2023.05.15.540745 — microbiology — Posted on 2024-08-16

2590 Instruction-tuned large language models misalign with natural language comprehension in humans

Gao, C.; Ma, Z.; Chen, J.; Li, P.; Huang, S.; Li, J.

10.1101/2024.08.15.608196 — neuroscience — Posted on 2024-08-16

2591 Assessing white matter plasticity in a randomized controlled trial of early literacy training in preschoolers

Caffarra, S.; Karipidis, I. I.; Kruper, J.; Kubota, E.; Richie-Halford, A.; Takada, M.; Rokem, A.; Yeatman, J. D.

10.1101/2024.08.16.608210 — neuroscience — Posted on 2024-08-16

2592 Deficiency of Orexin Receptor Type 1 in Dopaminergic Neurons Increases Novelty-Induced Locomotion and Exploration

Xiao, X.; Yeghiazaryan, G.; Eggersmann, F.; Cremer, A. L.; Backes, H.; Kloppenburg, P.; Hausen, A. C.

10.1101/2023.08.06.552140 — neuroscience — Posted on 2024-08-16

2593 Theta oscillations optimize a speed-precision trade-off in phase coding neurons

Amil, A. F.; Albesa-Gonzalez, A.; Verschure, P. F. M. J.

10.1101/2022.12.08.519523 — neuroscience — Posted on 2024-08-16

2594 A Memory Model of Rodent Spatial Navigation: Place Cells are Memories Arranged in a Grid and Grid Cells are Non-spatial

Huber, D. E.

10.1101/2023.12.30.573694 — neuroscience — Posted on 2024-08-17

2595 Matching dynamically varying forces with multi-motor-unit muscle models: A simulation study

Murtola, T.; Richards, C.

10.1101/2024.02.13.580042 — physiology — Posted on 2024-08-16

2596 Test-retest reliability of TMS motor evoked responses and silent periods during explosive voluntary isometric contractions.

Castelli, F.; Mian, O. S.; Bruton, A.; Chembila Valappil, A. C.; Tillin, N. A.

10.1101/2024.08.12.607577 — physiology — Posted on 2024-08-16

2597 Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions

Campos-Leon, K.; Ferguson, J.; Gunther, T.; Wood, C. D.; Wingett, S.; Pekel, S.; Varghese, C. S.; Varnai, C.; West, M.; Beggs, A.; Grundhoff, A.; Noyvert, B.; Roberts, S.; Parish, J. L.

10.1101/2024.08.16.608206 — microbiology — Posted on 2024-08-16

2598 Distinct Contributions of the Dorsal and Ventral Hippocampus to Spatial Working Memory and Spatial Coding in the Prefrontal Cortex

Babl, S. S.; Sigurdsson, T.

10.1101/2024.08.16.607133 — neuroscience — Posted on 2024-08-16

2599 Temporal and spatial niche partitioning in a retrotransposon community of the Drosophila genome

Varoqui, M.; Mohamed, M.; Mugat, B.; Gourion, D.; Lemoine, M.; Pelisson, A.; Grimaud, C.; Chambeyron, S.

10.1101/2024.08.14.607943 — genomics — Posted on 2024-08-16

2600 Distinct evolutionary trajectories following loss of RNA interference in Cryptococcus neoformans

Huang, J.; Larmore, C. J.; Priest, S. J.; Xu, Z.; Dietrich, F. S.; Yadav, V.; Magwene, P. M.; Sun, S.; Heitman, J.

10.1101/2024.08.15.608186 — genetics — Posted on 2024-08-16

2601 The Transcription Factor TCF21 is necessary for adoption of cell fates by Foxd1+ stromal progenitors during kidney development.

Finer, G.; Khan, M. D.; Zhou, Y.; Gadhvi, G.; Yacu, G. S.; Park, J.-S.; Gomez, R. A.; Sequeira-Lopez, M. L.; Quaggin, S. E.; Winter, D. R.

10.1101/2024.08.14.607910 — developmental biology — Posted on 2024-08-16

2602 Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease

Stone, C.; Harris, D. D.; Broadwin, M.; Kanuparthy, M.; Nho, J.-W.; Yalamanchili, K.; Hamze, J.; Abid, M. R.; Sellke, F. W.

10.1101/2024.08.15.608191 — molecular biology — Posted on 2024-08-16

2603 Ribosomal RNA transcription governs splicing through ribosomal protein RPL22

Fan, W.; Liu, H.; Stachelek, G. C.; Begum, A.; Davis, C. E.; Dorado, T. E.; Ernst, G.; Reinhold, W. C.; Ozbek, B.; Zheng, Q.; Marzo, A. M. D.; Rajeshkumar, N. V.; Barrow, J. C.; Laiho, M.

10.1101/2024.08.15.608201 — molecular biology — Posted on 2024-08-16

2604 Protective threshold of a potent neutralizing Zika virus monoclonal antibody in rhesus macaques

Nkolola, J.; Hope, D.; Guan, R.; Colarusso, A.; Aid, M.; Carnahan, R.; Crowe, J. E.; Barouch, D. H.

10.1101/2024.08.16.608231 — microbiology — Posted on 2024-08-16

2605 Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands

Tyrrell, C.; Burgess, C. M.; Brennan, F.; Muenzenmaier, D.; Drissner, D.; Leigh, R. J.; Walsh, F.

10.1101/2024.08.16.608224 — microbiology — Posted on 2024-08-16

2606 Placental and fetal microbiota in rhesus macaque: a case study using metagenomic sequencing

Du, Q.; Liu, X.; Zhang, R.; Hu, G.; Liu, Q.; Ma, W.; Hu, Y.; Fan, Z.; Li, J.

10.1101/2024.08.16.608220 — microbiology — Posted on 2024-08-16

2607 IdentifiHR: predicting homologous recombination deficiency in high-grade serous ovarian carcinoma using gene expression

Weir, A. L.; Lee, S. C.; Li, M.; Tan, C. W.; Ramus, S. J.; Davidson, N. M.

10.1101/2024.08.15.608185 — cancer biology — Posted on 2024-08-16

2608 Pressure protein denaturation compared to thermal and chemical unfolding - Analyses with cooperative models

Seelig, J.; Seelig, A.

10.1101/2024.08.14.608019 — biophysics — Posted on 2024-08-16

2609 P(all-atom) Is Unlocking New Path For Protein Design

Qu, W.; Guan, J.; Ma, R.; Zhai, K.; Wu, W.; Wang, H.

10.1101/2024.08.16.608235 — bioinformatics — Posted on 2024-08-16

2610 3D Microphysiological Tumor Model for Dual-Targeting CAR T Cell Immunotherapy

PENG, X.; Janicijevic, Z.; Loureiro, L. R.; Hoffmann, L.; Lee, P. S.; Cela, I.; Kruppke, B.; Kegler, A.; Feldmann, A.; Bachmann, M.; Baraban, L.

10.1101/2024.08.16.608227 — bioengineering — Posted on 2024-08-16

2611 Genomic analyses identify 15 susceptibility loci and reveal HDAC2, SOX2-OT, and IGF2BP2 in a naturally-occurring canine model of gastric cancer

Cook, S. R.; Hugen, S.; Hayward, J. J.; Famula, T. R.; Belanger, J. M.; McNiel, E.; Fieten, H.; Oberbauer, A. M.; Leegwater, P. A.; Ostrander, E. A.; Mandigers, P. J.; Evans, J. M.

10.1101/2024.08.14.604426 — genomics — Posted on 2024-08-16

2612 An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish

Carrothers, S.; Trevisan, R.; Jayasundara, N.; Pelletier, N.; Weeks, E.; Meyer, J. N.; Di Giulio, R. T.; Weinhouse, C.

10.1101/2024.08.14.607951 — genomics — Posted on 2024-08-16

2613 Comprehensive double-mutant analysis of the Bacillus subtilis envelope using double-CRISPRi

Koo, B.-M.; Todor, H.; Sun, J.; van Gestel, J.; Hawkins, J. S.; Hearne, C. C.; Banta, A. B.; Huang, K. C.; Peters, J. M.; Gross, C. A.

10.1101/2024.08.14.608006 — genomics — Posted on 2024-08-16

2614 EnteroBase in 2025: exploring the genomic epidemiology of bacterial pathogens

Dyer, N. P.; Pauker, B.; Baxter, L.; Gupta, A.; Bunk, B.; Overmann, J.; Diricks, M.; Dreyer, V.; Niemann, S.; Holt, K.; Rahman, M.; Brown, P. E.; Stark, R.; Zhou, Z.; Ott, S.; Nubel, U.

10.1101/2024.08.15.608032 — genomics — Posted on 2024-08-16

2615 Mutations in ErbB2 accumulating in the male germline measured by error-corrected sequencing

Yasari, A.; Heinzl, M.; Mair, T.; Karimian, T.; Moukbel, S. A.; Hartl, I.; Betancourt, A. J.; Lanzerstorfer, P.; Tiemann-Boege, I.

10.1101/2024.08.14.607923 — genetics — Posted on 2024-08-16

2616 Traffic Jam activates the Flamenco piRNA cluster locus and the Piwi pathway to ensure transposon silencing and Drosophila fertility.

Rivera, A.; Lee, J.-H. R.; Gupta, S.; Yang, L.; Goel, R. K.; Zaia, J.; Lau, N. C.

10.1101/2024.08.15.608167 — genetics — Posted on 2024-08-16

2617 MYH11 rare variant augments aortic growth and induces cardiac hypertrophy and heart failure with pressure overload

Zhou, Z.; Hughes, K.; Saif, N.; Kim, H.; Massett, M. P.; Zheng, M.; Cecchi, A. C.; Guo, D.; Murdock, D. R.; Pan, P.; Clinton, J. S.; Wang, J.; Greally, J. M.; Milewicz, D. M.

10.1101/2024.08.15.608063 — genetics — Posted on 2024-08-16

2618 S-RNase Evolution in Self-Incompatibility: Phylogenomic Insights into Synteny with S-Like Genes

Liu, Y.; Zhang, Y.; Han, S.; Guo, B.-C.; Liang, J.; Yu, Z.; Yang, F.; Sun, Y.; Xue, J.; Lin, Z.; Schranz, M. E.; Guan, C.; Ma, F.; Zhao, T.

10.1101/2024.08.14.607955 — evolutionary biology — Posted on 2024-08-16

2619 Simulation of neurotrophin receptor transmembrane helix interactions reveals active states and distinct signaling mechanisms

Athanasiou, C.; Claveras Cabezudo, A.; Tsengenes, A.; Wade, R. C.

10.1101/2024.08.16.608237 — molecular biology — Posted on 2024-08-16

2620 Ultrahigh-throughput discovery of modified aptamers as specific and potent enzyme inhibitors

Husser, C.; Hoetzel, J.; Cubi, R.; Lebars, I.; Kraus, L.; Di Primo, C.; Baudrey, S.; Proschak, E.; Kieffer, B.; Suess, B.; Ryckelynck, M.

10.1101/2024.08.16.608213 — molecular biology — Posted on 2024-08-16

2621 Impact of a defined bacterial community including and excluding Megamonas hypermegale on broiler cecal microbiota and resistance to Salmonella infection

Schultz Marcolla, C.; Ju, T.; Ten, K.; Sivakumar Sharma, U.; Moeun, L.; Willing, B. P.

10.1101/2024.08.15.608135 — microbiology — Posted on 2024-08-16

2622 Identification of stable reference genes in Edwardsiella ictaluri for accurate gene expression analysis

Lu, J.; Abdelhamed, H.; Al-Janabi, N.; Eissa, N.; Lawrence, M.; Karsi, A.

10.1101/2024.08.16.608217 — microbiology — Posted on 2024-08-16

2623 Dynein contributes to spindle elongation during anaphase in Candida albicans

Shoukat, I.; Allingham, J. S.

10.1101/2024.08.15.608126 — microbiology — Posted on 2024-08-16

2624 Study of excess manganese stress response highlights the central role of manganese exporter Mnx for holding manganese homeostasis in the cyanobacterium Synechocystis sp. PCC 6803

Reis, M.; Zenker, S.; Viehoever, P.; Niehaus, K.; Braeutigam, A.; Eisenhut, M.

10.1101/2024.08.16.608223 — microbiology — Posted on 2024-08-16

2625 EEG source imaging technique to investigate sleep oscillations for simultaneous EEG-fMRI

Uji, M.; Jegou, A.; Cross, N. E.; Pomares, F. B.; Perrault, A. A.; Nguyen, A.; Aydin, U.; Lee, K.; Abdallah, C.; Frauscher, B.; Lina, J.-M.; Dang-Vu, T. T.; Grova, C.

10.1101/2024.08.13.607843 — neuroscience — Posted on 2024-08-16

2626 AMH regulates ovary size by counteracting ovarian follicle cluster effects.

Lim, C.; Yiew, L.; Anderson, N. J.; Smith, P.; Quirke, L.; Carne, A.; Sarma, U.; Rose, R.; Nicholson, M.; Jasoni, C. L.; Liu, P.; Petrich, S.; Juengel, J.; Pankhurst, M. W.

10.1101/2024.08.15.607694 — physiology — Posted on 2024-08-16

2627 Premature cleavage and polyadenylation in the minor intron of PTEN modulate its expression and generates a functional long non-coding RNA in breast cancer

Elesnawy, M.; Elghandour, R.; Hasna, H.; Fakhroo, A.; Al-Sulaiti, B.; Younis, I.

10.1101/2024.08.15.608023 — cancer biology — Posted on 2024-08-16

2628 The abundance change of age-regulated secreted proteins affects lifespan of C. elegans

Bhunia, P. K.; Raj, V.; Kasturi, P.

10.1101/2024.08.16.608229 — biochemistry — Posted on 2024-08-16

2629 Chronic and Acute Mediators of Passive Viscoelasticity in Human Skeletal Muscle Fibers

Privett, G. E.; Ricci, A. W.; Wiedenfeld Needham, K.; Callahan, D. M.

10.1101/2024.08.13.607865 — biophysics — Posted on 2024-08-16

2630 Bioinspired Bimetallic Ions Functionalized MOF SAzyme Nanocomposites for Synergistic Ferroptosis/Cuproptosis-Enhanced Immune Checkpoint Therapy

Yang, L.; Pan, M.; Hu, H.; Liu, F.; Jiang, M.; Ning, S.; Chen, X.; Zhang, Z.; Yu, X.; Xu, L.

10.1101/2024.08.12.607118 — bioengineering — Posted on 2024-08-16

2631 High-fat diet exacerbates the loss of bone fracture toughness in aging for C57BL/6JN mice

Brown, K. C.; Vahidi, G.; Hislop, B. D.; Moody, M. C.; Watson, S.; Welhaven, H. D.; Behzad, R.; Paton, K.; Karim, L.; June, R. K.; Martin, S.; Heveran, C. M.

10.1101/2024.08.13.607633 — bioengineering — Posted on 2024-08-16

2632 Neuronal progenitors suffer genotoxic stress in the Drosophila clock mutant per0.

Colonna Romano, N.; Marchetti, M.; Marangoni, A.; Leo, L.; Retrosi, D.; Rosato, E.; Fanti, L.

10.1101/2024.08.13.607601 — genetics — Posted on 2024-08-16

2633 Mitochondrial calcium uniporter regulates human fibroblast-like synoviocytes invasion via altering mitochondrial dynamics and dictates rheumatoid arthritis pathogenesis

Promila, L.; Sarkar, K.; Guleria, S.; Rathore, M.; Singh, N. C.; Khan, S.; Tomar, M. S.; Ammanathan, V.; Barthwal, M. K.; Kumaravelu, J.; Shrivastava, A.; Mitra, K.; Guha, R.; Aggarwal, A.; Lahiri, A.

10.1101/2024.08.13.607857 — immunology — Posted on 2024-08-16

2634 Quantifying conformational changes in the TCR:pMHC-I binding interface

McMaster, B.; Thorpe, C.; Rossjohn, J.; Deane, C.; Koohy, H.

10.1101/2024.08.13.607715 — immunology — Posted on 2024-08-16

2635 The ageing stopping network: Regional and network changes in the IFG, preSMA, and STN across the adult lifespan

Kemp, S. A.; Bazin, P.-L.; Miletic, S.; Boag, R. J.; Keuken, M.; Hinder, M. R.; Forstmann, B.

10.1101/2024.08.13.607702 — neuroscience — Posted on 2024-08-16

2636 Contingency awareness shapes neural responses in fear conditioning

Pavlov, Y. G.; Menger, N. S.; Keil, A.; Kotchoubey, B.

10.1101/2024.08.13.607803 — neuroscience — Posted on 2024-08-16

2637 Network models incorporating chloride dynamics predict optimal strategies for terminating status epilepticus

Currin, C. B.; Burman, R. J.; Fedele, T.; Ramantani, G.; Rosch, R. E.; Sprekeler, H.; Raimondo, J. V.

10.1101/2024.08.13.607480 — neuroscience — Posted on 2024-08-16

2638 The brain simulates actions and their consequences during REM sleep

Senzai, Y.; Scanziani, M.

10.1101/2024.08.13.607810 — neuroscience — Posted on 2024-08-16

2639 Microbial reaction rate estimation using proteins and proteomes

McCain, J. S. P.; Britten, G. L.; Hackett, S. R.; Follows, M. J.; Li, G.-W.

10.1101/2024.08.13.607198 — systems biology — Posted on 2024-08-16

2640 Deep graph convolutional neural network for one-dimensional hepatic vascular haemodynamic prediction

Zhang, W.; Shi, S.; Qi, Q.

10.1101/2024.08.13.607720 — systems biology — Posted on 2024-08-16

2641 Low doses of the food contaminant Deoxynivalenol trigger apoptosis and alter GnRH stimulation of gonadotroph cells

Cai, G.; Yang, L.; Marien-Bourgeois, F.; Boerboom, D.; Zamberlam, G.; Alassane-Kpembi, I.

10.1101/2024.08.13.607800 — pharmacology and toxicology — Posted on 2024-08-16

2642 SynDRep: A Knowledge Graph-Enhanced Tool based on Synergistic Partner Prediction for Drug Repurposing

Shalaby, K. S.; Rao, S. G.; Schultz, B.; Hofmann-Apitius, M.; Tom Kodamullil, A.; Bharadhwaj, V. S.

10.1101/2024.08.13.607713 — bioinformatics — Posted on 2024-08-16

2643 Longitudinal metabolomics data analysis informed bymechanistic models

Li, L.; Hoefsloot, H. C.; Bakker, B. M.; Horner, D.; Rasmussen, M. A.; Smilde, A.; Acar, E.

10.1101/2024.08.13.607724 — bioinformatics — Posted on 2024-08-16

2644 FEDKEA: Enzyme function prediction with a large pretrained protein language model and distance-weighted k-nearest neighbor

Zheng, L.; Li, B.; Xu, S.; Chen, J.; Liang, G.

10.1101/2024.08.12.604109 — bioinformatics — Posted on 2024-08-16

2645 Predicting bacterial phenotypic traits through improved machine learning using high-quality, curated datasets

Koblitz, J.; Reimer, L. C.; Pukall, R.; Overmann, J.

10.1101/2024.08.12.607695 — bioinformatics — Posted on 2024-08-16

2646 Engineered Nanotopographies Induce Transient Openings in the Nuclear Membrane

Sarikhani, E.; Patel, V.; Li, Z.; Meganathan, D. P.; Rahmani, K.; Sadr, L.; Hosseini, R.; Visda, D.; Shukla, S.; Naghsh-Nilchi, H.; Balaji, A.; McMahon, G.; Chen, S.; Schoneberg, J.; McHugh, C. A.; Shi, L.; Jahed, Z.

10.1101/2024.08.13.605467 — bioengineering — Posted on 2024-08-16

2647 Exacerbation of influenza virus induced lung injury by alveolar macrophages and its suppression by pyroptosis blockade in a human lung alveolus chip

Man, Y.; Zhai, Y.; Jiang, A.; Bai, H.; Gulati, A.; Plebani, R.; Mannix, R. J.; Merry, G. E.; Goyal, G.; Belgur, C.; Hall, S. R. R.; Ingber, D. E.

10.1101/2024.08.13.607799 — bioengineering — Posted on 2024-08-16

2648 When monkeys meet an ANYmal robot in the wild

Canteloup, C.; Lee, J.; Zimmermann, S.; Alvino, M.; Montenegro, M.; Hutter, M.; van de Waal, E.

10.1101/2024.08.13.607714 — animal behavior and cognition — Posted on 2024-08-16

2649 Biologically-informed Killer cell immunoglobulin-like receptor (KIR) gene annotation tool

Ford, M. K. B.; Hari, A.; Zhou, Q.; Numanagic, I.; Sahinalp, S. C.

10.1101/2024.08.13.607835 — genomics — Posted on 2024-08-16

2650 Differences in maternal diet fiber content influence patterns of gene expression and chromatin accessibility in fetuses and piglets

Chalabi, S.; Loonen, L.; Boekhorst, J.; Li, H.; Fang, L.; Harrison, P. W.; Lakhal, W.; Lluch, J.; Sokolov, A.; Djebali, S.; Rau, A.; Giuffra, E.; Wells, J.

10.1101/2024.08.13.607725 — genomics — Posted on 2024-08-16

2651 Allopolyploidy expanded gene content but not pangenomic variation in the hexaploid oilseed Camelina sativa

Bird, K. A.; Brock, J. R.; Grabowski, P. P.; Harder, A. M.; Shu, S.; Barry, K.; Boston, L.; Daum, C.; Guo, J.; Lipzen, A.; Walstead, R.; Grimwood, J.; Schmutz, J.; Lu, C.; Edger, P. P.; Lovell, J. T.; Kliebenstein, D. J.

10.1101/2024.08.13.607619 — genomics — Posted on 2024-08-16

2652 Leveraging protein-protein interactions in phenotype prediction through graph neural networks

Smeriglio, R.; Rosell-Mirmi, J.; Radeva, P.; Abante, J.

10.1101/2024.08.13.605573 — genetics — Posted on 2024-08-16

2653 Eomes directs the formation of spatially and functionally diverse extra-embryonic hematovascular tissues

Theeuwes, B.; Harland, L. T.; Bisia, A.; Costello, I.; Ton, M.-L.; Lohoff, T.; Clark, S. J.; Argelaguet, R.; Wilson, N. K.; Reik, W.; Bikoff, E.; Robertson, E. J.; Gottgens, B.

10.1101/2024.08.13.607790 — developmental biology — Posted on 2024-08-16

2654 Targeting Interferon-Driven Inflammatory Memory Prevents Epigenetic Evolution of Cancer Immunotherapy Resistance

Qiu, J.; Ye, D.; Chen, X. E.; Dangle, N.; Yoshor, B.; Zhang, T.; Shao, Y.; Nallamala, V. C.; Wang, S.; Ren, D.; Xu, Y.; Chen, J.; Zhang, N. R.; Shi, J.; Greenberg, R. A.; Minn, A. J.

10.1101/2024.08.13.607862 — immunology — Posted on 2024-08-16

2655 Single-cell analysis identifies distinct CD4+ T cells associated with the pathobiology of pediatric obesity-related asthma

Thompson, D.; Wabara, Y.; Duran, S.; Reichenbach, A.; Chen, L.; Collado, K.; Yon, C.; Greally, J. M.; Rastogi, D.

10.1101/2024.08.13.607447 — immunology — Posted on 2024-08-16

2656 Parvalbumin expression identifies subicular principal cells with high projection specificity

Baccini, G.; Foggetti, A.; Wernet, N.; Engelhardt, K. A.; Kronenbitter, K.; Michels, J.; Kulik, A.; Wozny, C.; Wulff, P.

10.1101/2024.08.13.606964 — neuroscience — Posted on 2024-08-16

2657 The relationship between sleep and cognitive performance on tests of pattern separation

Roenningen, A. E.; Gill, D.; Kent, B. A.

10.1101/2024.08.13.607801 — neuroscience — Posted on 2024-08-16

2658 A Biologically Inspired Attention Model for Neural Signal Analysis

Skatchkovsky, N.; Glazman, N.; Sadeh, S.; Iacaruso, F.

10.1101/2024.08.13.607787 — neuroscience — Posted on 2024-08-16

2659 Age-dependent cortical overconnectivity revers under anesthesia in Shank3 mice

Montagni, E.; Ambrosone, M.; Martello, A.; Curti, L.; Baroncelli, L.; Mannaioni, G.; Pavone, F.; Masi, A.; Allegra Mascaro, A. L.

10.1101/2024.08.13.607775 — neuroscience — Posted on 2024-08-16

2660 Circadian gene Bmal1 in the lateral habenula regulates alcohol drinking behavior in a sex specific manner

Goldfarb, C.; Hasenhundl, V.; Menasce, A.; Amir, S.; Schottner, K.

10.1101/2024.08.13.607765 — neuroscience — Posted on 2024-08-16

2661 Behavior- and circuit-specific cortico-striatal decoupling during the early development of Parkinson's disease-like syndrome

Yao, X.-R.; Liu, Y.; Zheng, W.-T.; He, K.-W.

10.1101/2024.08.13.607859 — neuroscience — Posted on 2024-08-16

2662 Single-cell DNA methylation analysis tool Amethyst reveals distinct noncanonical methylation patterns in human glial cells

Rylaarsdam, L. E.; Nichols, R. V.; O'Connell, B. L.; Coleman, S.; Yardimci, G.; Adey, A. C.

10.1101/2024.08.13.607670 — neuroscience — Posted on 2024-08-16

2663 Mapping eye, arm, and reward information in frontal motor cortices using electrocorticography in non-human primates

Ouchi, T.; Scholl, L. R.; Rajeswaran, P.; Canfield, R. A.; Smith, L. I.; Orsborn, A. L.

10.1101/2024.08.13.607846 — neuroscience — Posted on 2024-08-16

2664 Exploring tropical freshwater soundscapes in Southeast Asia: insights into auditory sensory adaptation of wild Siamese fighting fish Betta splendens

Ramos, A.; Goncalves, D.; Vasconcelos, R. O.

10.1101/2024.08.13.607752 — zoology — Posted on 2024-08-16

2665 Improving the accuracy of cerebral blood flow measurement by phase contrast MRI

yang, x.

10.1101/2024.08.13.607816 — physiology — Posted on 2024-08-16

2666 Development of a preclinical screening platform for clinically relevant therapy of Dravet syndrome

Mensah, J. A.; Thomson, K. E.; Huff, J. L.; Freeman, T.; Reilly, C. A.; Rower, J. E.; Metcalf, C. S.; Wilcox, K. S.

10.1101/2024.08.13.607806 — pharmacology and toxicology — Posted on 2024-08-16

2667 Proteochemometric modeling strengthens the role of Q299 for GABA transporter subtype selectivity

Kickinger, S.; Seiler, A.; Digles, D.; Ecker, G. F.

10.1101/2024.08.13.607728 — pharmacology and toxicology — Posted on 2024-08-16

2668 Silver nanoparticle induced immunogenic cell death can improve immunotherapy

Sargsian, A.; Koutsoumpou, X.; Girmatsion, H.; Buttiens, K.; Rios Luci, C.; Soenen, S. J.; Manshian, B. B.

10.1101/2024.08.13.607617 — cancer biology — Posted on 2024-08-16

2669 Automated microinjection for zebrafish xenograft models

Ding, Y.; van der Kolk, K.-J.; van der Ent, W.; Scotto di Mase, M.; Kowald, S.; Huizing, J.; Vidal Teuton, J. M.; Mishra, G.; Kempers, M.; Almter, R.; Munier, L.; Di Donato, V.; Dyballa, S.; ten Dijke, P.; Esguerra, C. V.; Jensen, L. D.; de Sonneville, J.

10.1101/2024.08.13.607596 — cancer biology — Posted on 2024-08-16

2670 Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer

Rodriguez-Martinez, A.; Giraldo-Ruiz, L.; Ramos, M. C.; Luque, I.; Ribeiro, D.; Postigo-Corrales, F.; Alburquerque-Gonzalez, B.; Montoro-Garcia, S.; Arroyo-Rodriguez, A. B.; Conesa-Zamora, P.; Hurtado, A. M.; Luengo-Gil, G.; Perez-Sanchez, H.

10.1101/2024.08.13.606007 — cancer biology — Posted on 2024-08-16

2671 VIPER-TACs leverage viral E3 ligases for disease-specific targeted protein degradation

Mangano, K.; Guenette, R. G.; Hill, S.; Li, S.; Yang, S. W.; Ashton, K. S.; Potts, P. R.

10.1101/2024.08.13.607762 — cancer biology — Posted on 2024-08-16

2672 Self-assembly of mycolic acid in water: monolayer or bilayer

Kumar, Y.; Basu, S.; Maiti, P. K.

10.1101/2024.08.13.607716 — biophysics — Posted on 2024-08-16

2673 Sequence-encoded Spatiotemporal Dependence of Viscoelasticity of Protein Condensates Using Computational Microrheology

Sundaravadivelu Devarajan, D.; Mittal, J.

10.1101/2024.08.13.607792 — biophysics — Posted on 2024-08-16

2674 Comparative Analysis of Polysaccharide and Cell Wall Structure in Aspergillus nidulans and Aspergillus fumigatus by Solid-State NMR

Gautam, I.; Yarava, J. R.; Xu, Y.; Li, R.; Scott, F. J.; Mentink-Vigier, F.; Momany, M.; Latge, J.-P.; Wang, T.

10.1101/2024.08.13.607833 — biophysics — Posted on 2024-08-16

2675 Muscular expression of pezo-1 differentially contributes to swimming and crawling production in the nematode C. elegans.

Fazyl, A.; Sawilchik, E.; Stein, W.; Vidal-Gadea, A. G.

10.1101/2024.08.13.607367 — biophysics — Posted on 2024-08-16

2676 A method to increase the imaging efficiency of tiling light sheet microscopy using scanning non-coaxial beam arrays synchronized with regional virtual confocal slits

Gao, L.

10.1101/2024.08.13.607820 — biophysics — Posted on 2024-08-16

2677 A quantitative pipeline for whole-mount deep imaging and multiscale analysis of gastruloids

Gros, A.; Vanaret, J.; Dunsing-Eichenauer, V.; Rostan, A.; Roudot, P.; Lenne, P.-F.; Guignard, L.; Tlili, S.

10.1101/2024.08.13.607832 — biophysics — Posted on 2024-08-16

2678 Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia

Su, L.; Din, L.; Williams, P. H.; Liu, Y.; Wang, R.; Dai, X.; Zhao, S.; Fu, H.; Zhao, X.; Wang, Q.; Li, Y.; Sang, H.; Waterhouse, R. M.; Zhai, Y.; Sun, C.

10.1101/2024.08.13.607144 — bioinformatics — Posted on 2024-08-16

2679 Cecelia: a multifunctional image analysis toolbox for decoding spatial cellular interactions and behaviour

Schienstock, D.; Hor, J. L.; Devi, S.; Mueller, S. N.

10.1101/2024.08.13.607845 — bioinformatics — Posted on 2024-08-16

2680 Integrating sequence composition information into microbial diversity analyses with k-mer frequency counting

Bokulich, N. A.

10.1101/2024.08.13.607770 — bioinformatics — Posted on 2024-08-16

2681 Miniaturizing, Modifying, and Augmenting Nature's Proteins with Raygun

Devkota, K.; Shonai, D.; Mao, J.; Soderling, S. H.; Singh, R.

10.1101/2024.08.13.607858 — bioinformatics — Posted on 2024-08-16

2682 CLR_ESP: Improved enzyme-substrate pair prediction using contrastive learning

Du, Z.; Fu, W.; Guo, X.; Caragea, D.; Li, Y.

10.1101/2024.08.13.607829 — bioinformatics — Posted on 2024-08-16

2683 In silico studies provide new structural insights into trans-dimerization of β1 and β2 subunits of the Na+,K+-ATPase

Ramirez Salinas, G.; Rosas-Trigueros, J. L.; Sosa Huerta, C.; Shoshani, L.; Martinez Archundia, M. T.

10.1101/2024.08.13.607722 — bioinformatics — Posted on 2024-08-16

2684 ComBat-met: Adjusting Batch Effects in DNA Methylation Data

Wang, J.

10.1101/2024.08.13.607838 — bioinformatics — Posted on 2024-08-16

2685 Using Dynamic Bayesian Optimization to Induce Desired Effects in the Presence of Motor Learning: a Simulation Study

Kim, G.; Chishty, H. A.; Sergi, F.

10.1101/2024.08.13.607783 — bioengineering — Posted on 2024-08-16

2686 KnowVolution of an efficient polyamidase through molecular dynamics simulations of incrementally docked oligomeric substrates

Puetz, H.; Illig, A.-M.; Vorobii, M.; Janknecht, C.; Contreras, F.; Flemig, F.; Schwaneberg, U.

10.1101/2024.08.13.607760 — bioengineering — Posted on 2024-08-16

2687 Overcoming fixation and permeabilization challenges in flow cytometry by optical barcoding and multi-pass acquisition

Fahlberg, M. D.; Forward, S.; Assita, E. R.; Mazzola, M.; Kiem, A.; Handley, M.; Yun, S. H.; Kwok, S. J.

10.1101/2024.08.13.607771 — bioengineering — Posted on 2024-08-16

2688 Experimental and Computational Methods for Allelic Imbalance Analysis from Single-Nucleus RNA-seq Data

Simmons, S. K.; Adiconis, X.; Haywood, N.; Parker, J.; Lin, Z.; Liao, Z.; Tuncali, I.; Al'Khafaji, A.; Shin, A.; Jagadeesh, K.; Gosik, K.; Gatzen, M.; Smith, J. T.; El Kodsi, D. N.; Kuras, Y.; Baecher-Allan, C.; Serrano, G. E.; Beach, T. G.; Garimella, K.; Rozenblatt-Rosen, O.; Regev, A.; Dong, X.; Scherzer, C.; Levin, J. Z.

10.1101/2024.08.13.607784 — genomics — Posted on 2024-08-16

2689 Rhizosphere Microbiome Influence on Tomato Growth under Low-Nutrient Settings

Mejia, G.; Jara-Servin, A.; Romero-Chora, L.; Hernandez-Alvarez, C.; Peimbert, M.; Cruz-Ortega, R.; Alcaraz, L. D.

10.1101/2024.08.13.607683 — genomics — Posted on 2024-08-16

2690 Predicting the global economic costs of biological invasions by tetrapods

Bodey, T.; Cuthbert, R.; Diagne, C.; Marino, C.; Turbelin, A.; Angulo, E.; Fantle-Lepczyk, J.; Pincheira-Donoso, D.; Courchamp, F.; Hudgins, E.

10.1101/2024.08.15.606318 — ecology — Posted on 2024-08-16

2691 Weed Instance Segmentation from UAV ortho-mosaic Images based on Deep Learning

Lu, C.; Yu, K.

10.1101/2024.08.13.607729 — ecology — Posted on 2024-08-16

2692 Borrelia burgdorferi Secretes c-di-AMP as an Extracellular Pathogen-Associated Molecular Pattern to Elicit Type I Interferon Responses in Mammalian Hosts

Priya, R.; Ye, M.; Raghunanadanan, S.; Liu, Q.; Li, W.; Yu, Q.; Lou, Y.; Sintim, H. O.; Yang, X. F.

10.1101/2024.08.13.607721 — immunology — Posted on 2024-08-16

2693 Distinct bandwidths of orexin neuron activity independently encode body movement and metabolic state

Tesmer, A. L.; Viskaitis, P.; Donegan, D.; Bracey, E.; Grujic, N.; Patriarchi, T.; Peleg-Raibstein, D.; Burdakov, D.

10.1101/2024.08.13.607750 — neuroscience — Posted on 2024-08-16

2694 Shared and Unique Neural Codes for Biological Motion Perception in Humans and Macaque Monkeys

Cheng, Y.; Xin, Y.; Lu, X.; Yang, T.; Ma, X.; Yuan, X.; Liu, N.; Jiang, Y.

10.1101/2024.08.13.607730 — neuroscience — Posted on 2024-08-16

2695 Memorize multiple phase pattern attractors in nonlinear coupled oscillators dynamic via heterogeneous connectivity strength

Yao, R.; Li, Y.; Yao, X.; Wang, K.; Qu, J.; Zou, X.; HONG, B.

10.1101/2024.08.13.607707 — neuroscience — Posted on 2024-08-16

2696 Audiomotor prediction errors drive speech adaptation even in the absence of overt movement

Parrell, B.; Naber, C.; Kim, O. A.; Niziolek, C. A.; McDougle, S. D.

10.1101/2024.08.13.607718 — neuroscience — Posted on 2024-08-16

2697 A design principle of slow-wave sleep firing pattern with Na+ dynamics

Sato, T. R.; Ode, K. L.; Kinoshita, F. L.; Ueda, H. R.

10.1101/2024.08.13.607682 — systems biology — Posted on 2024-08-16

2698 Co-release of GABA and ACh from medial olivocochlear neurons fine tunes cochlear efferent inhibition

Castagnola, T.; Castagna, V. C.; Kitcher, S.; Torres Cadenas, L.; Di Guilmi, M. N.; Gomez Casati, M. E.; Buonfiglio, P. I.; Dalamon, V.; Katz, E.; Elgoyhen, A. B.; Weisz, C.; Goutman, J.; Wedemeyer, C.

10.1101/2024.08.12.607644 — physiology — Posted on 2024-08-16

2699 Implementation and calibration of spectroscopic single-molecule localization microscopy

Brenner, B.; Yeo, W.-H.; Lee, Y.; Kweon, J.; Sun, C.; Zhang, H. F.

10.1101/2024.08.15.608177 — bioengineering — Posted on 2024-08-16

2700 scatterbar: an R package for visualizing proportional data across spatially resolved coordinates

Velazquez, D.; Fan, J.

10.1101/2024.08.14.606810 — bioinformatics — Posted on 2024-08-16

2701 Complete genome sequences of two new strains of the shipworm endosymbiont, Teredinibacter turnerae

Gasser, M. T.; Flatau, R.; Altamia, M. A.; Filone, C. M.; Distel, D. L.

10.1101/2024.08.13.607755 — genomics — Posted on 2024-08-16

2702 Enhanced Suppression of Stenotrophomonas maltophilia by a Three-Phage Cocktail: Genomic Insights and Kinetic Profiling

Monsibais, A. N.; Tea, O.; Ghatbale, P.; Phan, J.; Lam, K.; Paulson, M.; Tran, N.; Suder, D. S.; Blanc, A.; Samillano, C.; Suh, J.; Dunham, S. J. B.; Gonen, S.; Pride, D. T.; Whiteson, K.

10.1101/2024.08.14.607921 — microbiology — Posted on 2024-08-16

2703 Differential EBV protein-specific antibody response between responders and non-responders to EBVSTs immunotherapy

Sarathkumara, Y.; Van Bibber, N. W.; Liu, Z.; Heslop, H. E.; Rouce, R. H.; Coghill, A. E.; Rooney, C. M.; Proietti, C.; Doolan, D.

10.1101/2024.08.14.607997 — microbiology — Posted on 2024-08-16

2704 Imaging high-frequency voltage dynamics in multiple neuron classes of behaving mammals

Haziza, S.; Chrapkiewicz, R.; Zhang, Y.; Kruzhilin, V.; Li, J.; Li, J.; Delamare, G.; Swanson, R.; Buzsaki, G.; Kannan, M.; Vasan, G.; Lin, M. Z.; Zeng, H.; Daigle, T. L.; Schnitzer, M. J.

10.1101/2024.08.15.607428 — neuroscience — Posted on 2024-08-16

2705 Dopaminergic modulation of behavioral and electrocortical markers of interpersonal performance monitoring in Parkinson's Disease: insights from multivariate and univariate analyses

Era, V.; Pesci, U. G.; Moreau, Q.; Pezzetta, R.; Zabberoni, S.; Peppe, A.; Costa, A.; Taglieri, S.; Candidi, M.; Aglioti, S. M.

10.1101/2024.08.14.607937 — neuroscience — Posted on 2024-08-16

2706 Brain transcriptomic signatures for mood disorders and suicide phenotypes: an anterior insula and subgenual ACC network postmortem study

Arasappan, D.; Spears, A.; Shah, S.; Mayfield, R. D.; Akula, N.; McMahon, F. J.; Jabbi, M.

10.1101/2024.08.14.606080 — neuroscience — Posted on 2024-08-16

2707 Gray matter correlates of childhood maltreatment in the context of major depression: searching for replicability in a multi-cohort brain-wide association study of 3225 adults

Goltermann, J.; Winter, N. R.; Meinert, S.; Grotegerd, D.; Kraus, A.; Flinkenflügel, K.; Altegoer, L.; Krieger, J.; Leehr, E. J.; Böhnlein, J.; Bonnekoh, L. M.; Richter, M.; Hahn, T.; Fisch, L.; Gruber, M.; Hermesdorf, M.; Berger, K.; Arolt, V.; Brosch, K.; Stein, F.; Thomas-Odenthal, F.; Usemann, P.; Teutenberg, L.; Hammes, V.; Jamalabadai, H.; Alexander, N.; Straube, B.; Jansen, A.; Nenadic, I.; Kircher, T.; Opel, N.; Dannlowski, U.

10.1101/2024.08.15.608132 — neuroscience — Posted on 2024-08-16

2708 Low-pass nanopore sequencing for measurement of global methylation levels in plants

Liau, Y.; Whibley, A.; Hill, A. M.; Vanga, B. R.; Pither-Joyce, M.; Hilario, E.; Bailey, S.; Thomson, S.; Lizamore, D.

10.1101/2024.08.12.607255 — genomics — Posted on 2024-08-16

2709 Circulating extracellular microRNAs in the blood promote sociability in mice

Dohi, E.; Matoba, K.; Garcia, P. A.; Francis-Oliveira, J.; Anguiano, F.; Kochi, T.; Badrani, J. H.; See, J.; Ito, N.; Mitani, R.; Rose, I. V.; Choi, E. Y.; Imai, T.; Crossman, D. K.; Pletnikov, M. V.; Witwer, K. W.; Niwa, M.; Kano, S.

10.1101/2024.08.12.605506 — neuroscience — Posted on 2024-08-16

2710 TissuePlot: A Multi-Scale Interactive Visualization Tool for Spatial Data

Khawatmi, M.; Sailem, H.

10.1101/2024.08.14.607906 — bioinformatics — Posted on 2024-08-16

2711 Global adaptive evolution involved in neuroticism and educational behaviors through the spread of anatomically modern humans

Hayakawa, T.; Fujito, N. T.; Moriya, Y.; Terahara, M.; Teshima, K. M.; Takahata, N.; Satta, Y.

10.1101/2024.08.13.604521 — evolutionary biology — Posted on 2024-08-16

2712 ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses

Catanzaro, N.; Wu, Z.; Fan, C.; Schaefer, A.; Yount, B.; Bjorkman, P.; Baric, R. S.; Letko, M. C.

10.1101/2024.03.13.584892 — microbiology — Posted on 2024-08-16

2713 Differences in isotopic compositions of individual grains and aggregated seed samples affect interpretation of ancient plant cultivation practices

James, N. F.; Winter-Schuh, C.; Kenoyer, J. M.; Guedes, J. D.; Makarewicz, C. A.

10.1101/2024.08.15.607704 — plant biology — Posted on 2024-08-16

2714 A common phthalate replacement disrupts ovarian function in young adult mice

Potts, C.; Harbolic, A.; Murphy, M.; Jojy, M.; Hanna, C.; Nadeem, M.; Alahmadi, H.; Martinez, S.; Warner, G. R.

10.1101/2024.08.14.607936 — pharmacology and toxicology — Posted on 2024-08-16

2715 A compact prism-based microscope for high sensitive measurements in fluid biopsy

Perego, L.; Dallari, C.; Falciani, C.; Pini, A.; Gardini, L.; Credi, C.; Pavone, F. S.

10.1101/2024.08.13.607708 — biophysics — Posted on 2024-08-16

2716 RAF inhibitors activate the integrated stress response by direct activation of GCN2

Gilley, R.; Kidger, A. M.; Neill, G.; Severson, P.; Byrne, D. P.; Kenneth, N. S.; Bollag, G.; Zhang, C.; de Oliveira, T. M.; Eyers, P.; Bayliss, R.; Masson, G. R.; Cook, S. J.

10.1101/2024.08.15.607884 — biochemistry — Posted on 2024-08-16

2717 Evaluation of long-read sequencing for Ostreid herpesvirus type 1 genome characterization from Magallana gigas infected tissues

Dotto-Maurel, A.; Pelletier, C.; Degremont, L.; Heurtebise, S.; Arzul, I.; MORGA, B.; Chevignon, G.

10.1101/2024.08.13.607701 — genomics — Posted on 2024-08-16

2718 Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation

Kaplan, M. M.; Hudacova, E.; Matejcek, M.; Tuaima, H.; Krivanek, J.; Machon, O.

10.1101/2024.08.13.607774 — developmental biology — Posted on 2024-08-16

2719 Astrogliosis And Neuroinflammation Underlie Scoliosis Upon Cilia Dysfunction

Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.

10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-08-16

2720 Circular RNA HMGCS1 sponges miR4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

Zhang, M.; Du, G.; Xie, L.; Xu, Y.; Chen, W.

10.1101/2024.03.06.583717 — cell biology — Posted on 2024-08-16

2721 Elexacaftor/tezacaftor/ivacaftor (Trikafta(R)) does not affect the growth of Aspergillus fumigatus in vitro

BIQUAND, E.; KHAU, S.; FOUQUENET, D.; COSTES, F.; Chesnay, A.; Desoubeaux, G.; BRIARD, B.

10.1101/2024.08.12.607675 — microbiology — Posted on 2024-08-16

2722 The new role of carbonic anhydrases and bicarbonate in acclimatization and hypoxia stress responses in Arabidopsis thaliana

Białas, A.; Dabrowska-Bronk, J.; Gawronski, P.; Karpinski, S.

10.1101/2024.08.13.607795 — plant biology — Posted on 2024-08-16

2723 Severe fire regimes decrease resilience of ectothermic populations

Sousa, H. C.; Malvasio, A.; Colli, G. R.; Salguero-Gomez, R. C.

10.1101/2023.06.25.546448 — ecology — Posted on 2024-08-16

2724 A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection

Fitzmeyer, E. A.; Dutt, T. S.; Pinaud, S.; Graham, B.; Gallichotte, E. N.; Hill, J. L.; Campbell, C.; Ogg, H.; Howick, V. M.; Lawniczak, M.; Osborne Nishimura, E.; Merkling, S. H.; Henao-Tamayo, M.; Ebel, G. D.

10.1101/2024.07.23.603613 — microbiology — Posted on 2024-08-16

2725 Fibroblastic FLT3L supports lymph node dendritic cells in the interfollicular niche

Lane, R. S.; Wu, S. Z.; Davidson, C.; Byrne, A.; Kayser, B.; Huang, H.; Williams, K.; Fernandez, M.; Jiang, J.; Zhang, J.; Asuncion, R.; Decalf, J.; Roose-Girma, M.; Lee, W.; McGinnis, L.; Warming, S.; Stephenson, W.; Rost, S.; Moussion, C.; Biancalani, T.; Muller, S.; Turley, S. J.

10.1101/2024.08.12.607692 — immunology — Posted on 2024-08-16

2726 Age-Related Differences in Human Cortical Microstructure Depend on the Distance to the Nearest Vein

Knoll, C.; Doehler, J.; Northall, A.; Schreiber, S.; Rotta, J.; Mattern, H.; Kuehn, E.

10.1101/2023.12.20.572529 — neuroscience — Posted on 2024-08-16

2727 Tunnelling nanotubules are druggable mediators of cancer-niche crosstalk.

Hockney, S.; Parker, J.; Tzivelekis, B.; Blair, H.; Dalgarno, K.; Pal, D.

10.1101/2023.06.20.545732 — cancer biology — Posted on 2024-08-16

2728 Identification of robust RT-qPCR reference genes for studying changes in gene expression in response to hypoxia in breast cancer cell lines

Malcolm, J. R.; Bridge, K. S.; Holding, A. N.; Brackenbury, W. J.

10.1101/2024.08.02.606329 — cancer biology — Posted on 2024-08-16

2729 Prognostic importance of splicing-triggered aberrations of protein complex interfaces in cancer

Newaz, K.; Schaefers, C.; Weisel, K.; Baumbach, J.; Frishman, D.

10.1101/2024.05.06.592695 — bioinformatics — Posted on 2024-08-16

2730 A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia

hua, X.; Zhao, C.; Tian, J.; Wang, J.; Miao, X.; Zheng, G.; Wu, M.; Ye, M.; Liu, Y.; Zhou, Y.

10.1101/2024.06.21.600033 — cell biology — Posted on 2024-08-16

2731 Centimeter-scale, physiologically relevant intestinal organoids generated entirely from pluripotent stem cells

Qi, Z.; Zuo, Z.; Dong, Y.; Shao, J.; Wang, C.; Zhang, R.

10.1101/2024.08.15.608057 — cell biology — Posted on 2024-08-16

2732 A PthXo2B ortholog in Xanthomonas oryzae pv oryzae strain IX-221 acts as a major virulence factor on indica rice without activating a Clade III SWEET gene.

Mishra, P.; S, S.; Carpenter, S. C. D.; Sekar, H.; S, V.; N, A. K.; Dash, P. K.; Bogdanove, A. J.; Rai, R.

10.1101/2024.08.08.607113 — plant biology — Posted on 2024-08-16

2733 Morpho-physiological and transcriptomic responses of field pennycress to waterlogging

Combs-Giroir, R.; Shah, M.; Chhetri, H.; Morgan, M.; Prates, E. T.; Townsend, A.; Phippen, M. E.; Phippen, W. B.; Jacobson, D. A.; Gschwend, A. R.

10.1101/2024.08.15.608142 — plant biology — Posted on 2024-08-16

2734 Enhanced auxin signaling hub triggers root hair growth at moderate low temperature in Arabidopsis thaliana

Gabarain, V. B.; Nunez-Lillo, G.; Pencik, A.; Ibeas, M. A.; Pacheco, J. M.; Lopez, L. E.; Carignani, M.; Zhongtao, J.; Novak, O.; Giehl, R. F. H.; von Wiren, N.; Meneses, C.; Estevez, J.

10.1101/2024.08.15.608078 — plant biology — Posted on 2024-08-16

2735 Placodiscus bijugus (Sapindaceae) a new species of Endangered lowland evergreen forest tree from the western foothills of Mt Cameroon and from Korup National Park, Cameroon.

Gosline, G.; Ndam, N.; Cable, S.; Cheek, M.

10.1101/2024.08.14.607904 — plant biology — Posted on 2024-08-16

2736 DNAAF9 (Shulin) and ARL3 regulate the transport and activation of ciliary Outer Dynein Arms

Housseini B Issa, K.; Ren, M.; Burnet, B.; Melia, C.; Heesom, K.; Mali, G. R.

10.1101/2024.08.15.608058 — cell biology — Posted on 2024-08-16

2737 Calcium tunneling through the entoplasmic reticulum and transfer to other organelles for optimal signaling in Toxoplasma gondii

Li, Z.-H.; Asady, B.; Chang, L.; Hortua Triana, M. A.; Li, C.; Coppens, I.; Moreno, S. N.

10.1101/2024.08.15.608087 — cell biology — Posted on 2024-08-16

2738 Developmental stage determines the realized energy landscape for a flight specialist

Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J. S.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.

10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-08-16

2739 Failure to Resolve Inflammation Contributes to Juvenile-Onset Cardiomyopathy in a Mouse Model of Duchenne Muscular Dystrophy

Novak, J. S.; Lischin, A.; Uapinyoying, P.; Hindupur, R.; Moon, Y. J.; Bhattacharya, S.; Tiufekchiev, S.; Barone, V.; Mazala, D. A.; Gamu, I. H.; Walters, G.; Panchapakesan, K.; Jaiswal, J. K.

10.1101/2024.08.15.607998 — cell biology — Posted on 2024-08-15

2740 New imaging tools reveal live cellular collagen secretion, fibril dynamics and network organisation.

Kent, O.; Casey, E. R.; Brown, M.; Bell, S.; Ehrman, M. C.; Flagler, M. J.; Maatta, A.; Benham, A. M.; HAWKINS, T. J.

10.1101/2024.08.15.608104 — cell biology — Posted on 2024-08-15

2741 Centimeter-scale, physiologically relevant intestinal organoids generated entirely from pluripotent stem cells

Qi, Z.; Zuo, Z.; Dong, Y.; Shao, J.; Wang, C.; Zhang, R.

10.1101/2024.08.15.608057 — cell biology — Posted on 2024-08-16

2742 Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta

Williamson, A. E.; Liyanage, S.; Hassanshahi, M.; Dona, M. S. I.; Toledo-Flores, D.; Tran, D. X. A.; Dimasi, C.; Schwarz, N.; Fernando, S.; Salagaras, T.; Long, A.; Kazenwadel, J.; Harvey, N. L.; Drummond, G. R.; Vinh, A.; Chandrakanthan, V.; Misra, A.; Neufeld, Z.; Tan, J. T. M.; Martelotto, L. G.; Polo, J. M.; Bonder, C. S.; Pinto, A. R.; Sharma, S.; Nicholls, S. J.; Bursill, C. A.; Psaltis, P. J.

10.1101/2021.10.18.464001 — cell biology — Posted on 2024-08-16

2743 Membrane tension regulation is required for wound repair

Raj, N.; Weiss, M.; Vos, B. E.; Weischer, S.; Brinkmann, F.; Betz, T.; Trappmann, B.; Gerke, V.

10.1101/2024.08.15.608096 — cell biology — Posted on 2024-08-16

2744 Serum Amyloid P Secreted by Bone Marrow Adipocytes Drives Skeletal Amyloidosis

Kumar, S.; Song, K.; Wang, J.; Baghel, M. S.; Wong, P.; Cao, X.; Wan, M.

10.1101/2024.08.15.608092 — cell biology — Posted on 2024-08-16

2745 Novel high-content and open-source image analysis tools for profiling mitochondrial morphology in neurological cell models

Chin, M.; Joy, D.; Samaddar, M.; Rana, A.; Chow, J.; Miyamoto, T.; Calvert, M. E.

10.1101/2024.08.15.607824 — cell biology — Posted on 2024-08-16

2746 Chimeras of Kinesin-6 and Kinesin-14 reveal head-neck-tail domain functions and dysfunctions that lead to aneuploidy in fission yeast

Sasmal, P.; Miyazaki, M.; Carlier-Grynkorn, F.; Tran, P.

10.1101/2024.08.15.608119 — cell biology — Posted on 2024-08-16

2747 Investigation of cell mechanics and migration on DDR2-expressing neuroblastoma cell line

Vessella, T.; Rozen, E. J.; Shohet, J.; Wen, Q.; Zhou, H. S.

10.1101/2024.08.15.607761 — cell biology — Posted on 2024-08-16

2748 Sequence action representations contextualize during rapid skill learning

Dash, D.; Iwane, F.; Hayward, W.; Salamanca-Giron, R.; Bonstrup, M.; Buch, E.; Cohen, L.

10.1101/2024.08.15.608189 — neuroscience — Posted on 2024-08-15

2749 Hemoglobin as a peroxidase and drug target for oxidative stress-related diseases

Won, W.; Lee, E. H.; Gotina, L.; Chun, H.; Park, U.; Lee, J.-H.; Kim, D.; Kim, T. Y.; Choi, J.; Kim, Y.; Park, S. J.; Bhalla, M.; Lim, J.; Park, J.-H.; Oh, S.-J.; Ryu, H.; Pae, A. N.; Park, K. D.; Lee, C. J.

10.1101/2024.05.21.594979 — neuroscience — Posted on 2024-08-16

2750 Modelling medulloblastoma pathogenesis and treatment in human cerebellar organoids.

Willott, T. O.; Nicholson, J. G.; Xiao, Y.; Ogunbiyi, O. K.; Mistry, T.; Zabet, N. R.; Merve, A.; Badodi, S.; Marino, S.

10.1101/2024.08.14.607977 — cancer biology — Posted on 2024-08-15

2751 Microglia morphology in the developing primate amygdala and effects of early life stress

King, D. P.; Abdalaziz, M.; Majewska, A. K.; Cameron, J. L.; Fudge, J. L.

10.1101/2024.08.15.608133 — neuroscience — Posted on 2024-08-15

2752 Whole-brain dynamics of articulatory, acoustic and semantic speech representations

Verwoert, M.; Amigo-Vega, J.; Gao, Y.; Ottenhoff, M.; Kubben, P.; Herff, C.

10.1101/2024.08.15.608082 — neuroscience — Posted on 2024-08-15

2753 Working memory processing boosts the retrieval of existing long-term memory representations

Sabo, M.; Klatt, L. I.; Schneider, D.

10.1101/2024.08.15.608072 — neuroscience — Posted on 2024-08-15

2754 Moonlight Polarisation Pattern Guides Nocturnal Bull Ants Home

Freas, C. A.; Narendra, A.; Murray, T.; Cheng, K.

10.1101/2023.12.28.573574 — animal behavior and cognition — Posted on 2024-08-15

2755 The E3 ubiquitin ligase RNF220 maintains hindbrain Hox expression patterns through regulation of WDR5 stability

Wang, H.; Liu, X.; Liu, Y.; Yang, C.; Ye, Y.; Yu, X.; Sheng, N.; Zhang, S.; Mao, B.; Ma, P.

10.1101/2023.12.15.571884 — developmental biology — Posted on 2024-08-15

2756 Hundreds of myosin 10s are pushed to the tips of filopodia and could cause traffic jams on actin

Shangguan, J.; Rock, R. S.

10.1101/2023.06.26.546598 — cell biology — Posted on 2024-08-15

2757 Annotation of piRNA source loci in the genome of non-model insects

Halbach, R.; van Rij, R. P.

10.1101/2024.08.15.608080 — molecular biology — Posted on 2024-08-15

2758 Ubiquitination mediates protein localization in RNA virus-infected cells

Shi, S.; Iesmantavicius, V.; Sabu, A. S.; Soneson, C.; Kohler, H.; Sanchez, J.; Ghosh, S.; Cao, C.; Huang, Y.; Matthias, G.; Yamauchi, Y.; Matthias, P.; Wang, L.

10.1101/2024.08.15.608034 — molecular biology — Posted on 2024-08-15

2759 Nuclear Translocation of SIRT4 Mediates Deacetylation of U2AF2 to Modulate Renal Fibrosis Through Alternative Splicing-mediated Upregulation of CCN2

Yang, G.; Xiang, J.; Yang, X.; Liu, X.; Li, Y.; Li, L.; Kang, L.; Liang, Z.; Yang, S.

10.1101/2024.04.30.591939 — molecular biology — Posted on 2024-08-15

2760 Discovering methylated DNA motifs in bacterial nanopore sequencing data with MIJAMP

Tidwell, A. K.; Faust, E.; Eckert, C. A.; Guss, A. M.; Alexander, W.

10.1101/2024.08.14.607972 — molecular biology — Posted on 2024-08-15

2761 Daxx mediated histone H3.3 deposition on HSV-1 DNA restricts genome decompaction and the progression of immediate-early transcription

Roberts, A. P. E.; Orr, A.; Iliev, V.; Orr, L.; McFarlane, S.; Yang, Z.; Epifano, I.; Loney, C.; Collados Rodriguez, M.; Cliffe, A. R.; Conn, K. L.; Boutell, C.

10.1101/2024.08.15.608064 — microbiology — Posted on 2024-08-15

2762 Predicting rifampicin resistance in M. tuberculosis using machine learning informed by protein structural and chemical features.

Lynch, C.; Adlard, D.; Fowler, P. W.

10.1101/2024.08.15.608097 — microbiology — Posted on 2024-08-15

2763 Allosteric Regulation of Pyruvate Kinase Enables Efficient and Robust Gluconeogenesis by Preventing Metabolic Conflicts and Carbon Overflow

She, F.; Anderson, B. W.; Khana, D. B.; Zhang, S.; Steinchen, W.; Fung, D. K. C.; Lucas, L. N.; Lesser, N. G.; Stevenson, D. M.; Astmann, T. J.; Bange, G.; van Pijkeren, J. P.; Amador-Noguez, D.; Wang, J. D.

10.1101/2024.08.15.607825 — microbiology — Posted on 2024-08-15

2764 UV-irradiated rotifers for the maintenance of gnotobiotic zebrafish larvae

Rosales, S. M.; Bouchard, P. I.; Olmstead, E. M.; Parthasarathy, R.

10.1101/2024.08.15.608160 — microbiology — Posted on 2024-08-15

2765 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells

DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.

10.1101/2024.07.31.606077 — immunology — Posted on 2024-08-15

2766 The impact of pubertal stress and adult hormone exposure on the transcriptome of the developing hypothalamus

Gautier, K. N.; Higley, S. L.; Mendoza, J. M.; Morrison, K. E.

10.1101/2023.10.03.559350 — neuroscience — Posted on 2024-08-15

2767 Biomechanical filtering supports efficient tactile encoding in the human hand

Tummala, N.; Reardon, G.; Dandu, B.; Shao, Y.; Saal, H. P.; Visell, Y.

10.1101/2023.11.10.565040 — neuroscience — Posted on 2024-08-15

2768 Rapid nongenomic estrogen signaling controls alcohol drinking behavior

Zallar, L. J.; Rivera-Irizarry, J. K.; Hamor, P. U.; Pigulevskiy, I.; Liu, D.; Welday, J. P.; Rico Rozo, A.-S.; Bender, R.; Asfouri, J.; Skelly, M. J.; Fecteau, K. M.; Hadley, C. K.; Levine, O. B.; Mehanna, H.; Nelson, S.; Miller, J.; Ghazal, P.; Bellotti, P.; Erikson, D. W.; Geri, J.; Pleil, K. E.

10.1101/2023.11.02.565358 — neuroscience — Posted on 2024-08-15

2769 Preclinical evaluation of the novel CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease

Zajicek, F.; Verhaeghe, J.; de Lombaerde, S.; Van Eetveldt, A.; Miranda, A.; Munoz-Sanjuan, I.; Dominguez, C.; Khetarpal, V.; Bard, J.; Liu, L.; Staelens, S.; Bertoglio, D.

10.1101/2024.05.16.594492 — neuroscience — Posted on 2024-08-15

2770 Membrane fusion-based drug delivery liposomes transiently modify the material properties of synthetic and biological membranes

Hammond, J.; Richards, C. J.; Ko, Y.; Jonker, T.; Aberg, C.; Roos, W. B.; Lira, R. B.

10.1101/2024.08.14.607934 — biophysics — Posted on 2024-08-15

2771 Achieve Handle Level Random Access in Encrypted DNA Archival Storage System via Frequency Dictionary Mapping Coding

Cao, B.; Li, X.; Wang, B.; He, T.; Zheng, Y.; Zhang, X.; Zhang, Q.

10.1101/2024.08.15.608111 — bioengineering — Posted on 2024-08-15

2772 The ubiquitin-proteasome system regulates the formation of specialized ribosomes during high salt stress in yeast

Karbstein, K.; Yang, Y.-M.

10.1101/2024.08.15.608112 — biochemistry — Posted on 2024-08-15

2773 SARS-CoV-2 and Mycobacterium tuberculosis co-infection in vitro

Lucena, T. M. C. d.; Miranda, D. E. O.; Arcoverde, J. V. B.; Cavalcanti, M. S. B.; Rabello, M. C. d. S.; Silva, J. d. A.

10.1101/2024.08.14.607914 — cell biology — Posted on 2024-08-15

2774 Chemotherapy causes a reversible decrease in VMP1/MIR21 DNA methylation in granulocytes from breast cancer survivors

Abrahamsen, M.-L.; Jachowicz, Z.; Buch-Larsen, K.; Marina, D.; Andersson, M.; Schwarz, P.; Dela, F.; Gillberg, L.

10.1101/2024.08.15.608076 — molecular biology — Posted on 2024-08-15

2775 Emerging Clostridioides difficile ribotypes have divergent metabolic phenotypes

Midani, F. S.; Danhof, H. A.; Mathew, N.; Ardis, C. K.; Garey, K. W.; Spinler, J. K.; Britton, R. A.

10.1101/2024.08.15.608124 — microbiology — Posted on 2024-08-15

2776 Cappable-Seq reveals the transcriptional landscape of stress responses in the bacterial endosymbiont Wolbachia

Suliman, Y. M.; Li, Z.; Sinha, A.; Dyer, P. D.; Hartley, C. S.; Darby, A. C.; Carlow, C. K. S.; Makepeace, B. L.

10.1101/2024.08.15.608088 — microbiology — Posted on 2024-08-15

2777 A widespread hydrogenase drives fermentative growth of gut bacteria in healthy people

Welsh, C.; Cabotaje, P. R.; Marcelino, V. R.; Watts, T. D.; Kountz, D. J.; Gould, J. A.; Doan, N. Q.; Lingford, J. P.; Solari, J.; D'Adamo, G. L.; Huang, P.; Bong, N.; Gulliver, E. L.; Young, R. B.; Walter, K.; Wolf, P. G.; Ridlon, J. M.; Gaskins, H. R.; Giles, E. M.; Lyras, D.; Lappan, R.; Berggren, G.; Forster, S. C.; Greening, C.

10.1101/2024.08.15.608110 — microbiology — Posted on 2024-08-15

2778 Competition and Compromise between Exogenous Probiotics and Native Microbiota

Han, Z.; Sun, Z.; Zhao, Q.; Du, L.; Zhen, D.; Liu, X.; Jiang, S.; Liu, Y.-Y.; Zhang, J.

10.1101/2024.08.15.608074 — microbiology — Posted on 2024-08-15

2779 HSP90 interacts with VP37 to facilitate the cell-to-cell movement of broad bean wilt virus 2

Kim, M.-H.; Jang, S.-Y.; Choi, J.-S.; Kim, S.; Lee, Y.; Park, S.; Kwon, S.-J.; Seo, J.-K.

10.1101/2024.08.15.608091 — microbiology — Posted on 2024-08-15

2780 Viral and bacterial plant pathogens suppress antiviral defense against flaviviruses in their insect vectors

Larrea-Sarmiento, A. E.; Olmedo-Velarde, A.; West-Ortiz, M.; Stuehler, D.; Hosseinzadeh, S.; Coleman, A.; Preising, S.; Parker, G.; Fei, Z.; Heck, M. L.

10.1101/2024.08.15.608128 — microbiology — Posted on 2024-08-15

2781 Semi-Automatic Segmentation of Pseudomonas koreensis and Escherichia coli for Bacterial Growth Characterization

Alvarado-Ruiz, D. A.; Ordaz-Hernandez, K.; Diaz-Jiminez, L.; Lara-Cadena, G. L.; Gonzalez-Lopez, R.; Vargas-Gutierrez, G.; Castelan, M.

10.1101/2024.08.15.608040 — microbiology — Posted on 2024-08-15

2782 Human-derived microRNA 21 regulates indole and L-tryptophan biosynthesis transcripts in a prominent gut symbiont

Flanagan, K.; Gassner, K.; Lang, M.; Ozelyte, J.; Hausmann, B.; Crepaz, D.; Pjevac, P.; Gasche, C.; Berry, D.; Vesely, C.; Pereira, F. C.

10.1101/2024.08.15.608161 — microbiology — Posted on 2024-08-15

2783 Hatching of whipworm eggs induced by bacterial contact is serine-protease dependent

Goulding, D.; Tolley, C.; Mkandawire, T. T.; Doyle, S. R.; Hart, E.; Airs, P. M.; Grencis, R. K.; Berriman, M.; Duque-Correa, M. A.

10.1101/2024.08.15.608065 — microbiology — Posted on 2024-08-15

2784 Methanogenesis inhibition remodels microbial fermentation and stimulates acetogenesis in ruminants

Ni, G.; Walker, N.; Fischer, A.; Stemmler, R. T.; Schmidt, O.; Jain, S.; Jespersen, M.; Grinter, R.; Wang, M.; Pope, P. B.; Muller, V.; Watson, M.; Ver Loren van Themaat, E.; Kindermann, M.; Greening, C.

10.1101/2024.08.15.608071 — microbiology — Posted on 2024-08-15

2785 Coupling of secondary metabolite production in Bacillus subtilis

Dinesen, C.; Vertot, M.; Jarmusch, S. A.; Lozano-Andrade, C. N.; Andersen, A.; Kovacs, A. T.

10.1101/2024.08.15.608099 — microbiology — Posted on 2024-08-15

2786 AAB-seq: An antigen-specific and affinity-readable high-throughput BCR sequencing method

Hu, M.; Lian, Q.; Cui, X.; Dong, X.; Xin, H.; Shi, W.

10.1101/2024.08.13.607736 — immunology — Posted on 2024-08-15

2787 Identification of biomarkers for COVID-19 associated secondary hemophagocytic lymphohistiocytosis

Canny, S. P.; Stanaway, I. B.; Holton, S. E.; Mitchem, M. A.; O'Rourke, A.; Pribitzer, S.; Baxter, S. K.; Wurfel, M. M.; Malhotra, U.; Buckner, J. H.; Bhatraju, P. K.; Morrell, E. D.; Speake, C.; Mikacenic, C.; Hamerman, J.

10.1101/2024.08.13.607855 — immunology — Posted on 2024-08-15

2788 Profiling serum immunodominance following SARS-CoV-2 primary and breakthrough infection reveals distinct variant-specific epitope usage and immune imprinting.

Seow, J.; Jefferson, G. C. E.; Keegan, M.; Yau, Y.; Snell, L. B.; Doores, K. J.

10.1101/2024.08.14.607882 — immunology — Posted on 2024-08-15

2789 Tailoring hydrophobicity and strength in spider silk-inspired coatings via thermal treatments

Seisto, A.; Borisova, A. S.; Pylkkanen, R.; Mohammadi, p.

10.1101/2024.08.12.607662 — bioengineering — Posted on 2024-08-15

2790 PhOxi-seq detects enzyme-dependent m2G in multiple RNA types

Klimontova, M.; Chung, K. C. K.; Zhang, H.; Kouzarides, T.; Bannister, A. J.; Hili, R.

10.1101/2024.08.15.608094 — biochemistry — Posted on 2024-08-15

2791 Spatial mapping of immunosuppressive cancer-associated fibroblast gene signatures in H&E-stained images using additive multiple instance learning

Markey, M.; Kim, J.; Goldstein, Z.; Gerardin, Y.; Brosnan-Cashman, J.; Javed, S. A.; Juyal, D.; Padigela, H.; Yu, L.; Rahsepar, B.; Abel, J.; Hennek, S.; Khosla, A.; Taylor-Weiner, A.; Parmar, C.

10.1101/2024.08.12.607604 — cancer biology — Posted on 2024-08-15

2792 DeepAge: Harnessing Deep Neural Network for Epigenetic Age Estimation FromDNA Methylation Data of human blood samples

Dip, S. A.; Ma, D.; ZHANG, L.

10.1101/2024.08.12.607687 — bioinformatics — Posted on 2024-08-15

2793 Open-source 3D printed manifolds for exposure studies using human airway epithelial cells

Singer, R.; Ball, E.; Milad, N.; Nguyen, J. P.; Cao, Q.; Selvaganapathy, P. R.; Zhang, B.; Dabaghi, M.; Satia, I.; Hirota, J. A.

10.1101/2024.08.12.607646 — bioengineering — Posted on 2024-08-15

2794 Revealing the Auxetic Behavior of Biomimetic Multi-material and Region-specific Nanofibrous Scaffolds via Synchrotron Multiscale Digital Volume Correlation: Innovative Building Blocks for the Enthesis Regeneration

Sensini, A.; Giacomini, F.; Stamati, O.; Lukic, B.; Villanova, J.; Proudhon, H.; Gille, M.; Birgani, Z. T.; Truckenmuller, R.; Tozzi, G.; van Griensven, M.; Moroni, L.

10.1101/2024.08.12.607645 — bioengineering — Posted on 2024-08-15

2795 The role of mitochondrial complex I in the proinflammatory response to polylactide implants

Maduka, C. V.; Makela, A. V.; Tundo, A.; Ural, E.; Stivers, K. B.; Alhaj, M.; Narayan, R.; Goodman, S. B.; Ashammakhi, N.; Elisseeff, J. H.; Hankenson, K. D.; Contag, C. H.

10.1101/2024.08.12.607680 — bioengineering — Posted on 2024-08-15

2796 The effect of microsaccades in the primary visual cortex: a two-phase modulation in the absence of visual stimulation

Nativ, Y.; Bouhnik, T.; Slovin, H.

10.1101/2024.08.12.607606 — neuroscience — Posted on 2024-08-15

2797 Male and female mice respectively form stronger social aversive memories with same and different sex conspecifics

Beaver, J. N.; Nicodemus, M. M.; Spalding, I. R.; Dutta, S.; Jasnow, A. M.; Gilman, T. L.

10.1101/2024.08.12.607663 — neuroscience — Posted on 2024-08-15

2798 Explicitly Nonlinear Connectivity-Matrix Independent Component Analysis in Resting fMRI Data

Motlaghian, S.; Calhoun, V.

10.1101/2024.08.12.607681 — neuroscience — Posted on 2024-08-15

2799 Protamine Protects Against Vancomycin Induced Kidney Injury

Shiau, J.; Engel, P.; Olsen, M.; Pais, G.; Chang, J.; Scheetz, M. H.

10.1101/2024.08.12.607677 — pharmacology and toxicology — Posted on 2024-08-15

2800 A hollow fiber membrane-based liver organoid-on-a-chip model for examining drug metabolism and transport

Myszczyszyn, A.; Muench, A.; Lehmann, V.; Sinnige, T.; van Steenbeek, F. G.; Bouwmeester, M.; Samsom, R.-A.; Keuper-Navis, M.; van der Made, T. K.; Kogan, D.; Braem, S.; van der Laan, L. J. W.; Eslami Amirabadi, H.; van de Steeg, E.; Masereeuw, R.; Spee, B.

10.1101/2024.08.12.607504 — pharmacology and toxicology — Posted on 2024-08-15

2801 Dominant Malignant Clones Leverage Lineage Restricted Epigenomic Programs to Drive Ependymoma Development

Kardian, A.; Sun, H.; Ippagunta, S.; Laboe, N.; Chen, H.-C.; Emanus, E.; Varadharajan, S.; Zheng, T.; Holcomb, B.; Connelly, P.; Connelly, J. P.; Wang, M.; Lowe, K.; Pruett-Miller, S.; Bertrand, K. C.; Deneen, B.; Mack, S. C.

10.1101/2024.08.12.607603 — cancer biology — Posted on 2024-08-15

2802 Cryo-EM Heterogeneity Analysis using Regularized Covariance Estimation and Kernel Regression

Gilles, M. A. T.; Singer, A.

10.1101/2023.10.28.564422 — bioinformatics — Posted on 2024-08-15

2803 Comprehensive evaluation and practical guideline of gating methods for high-dimensional cytometry data: manual gating, unsupervised clustering, and auto-gating

Liu, P.; Pan, Y.; Chang, H.-C.; Fang, Y.; Xue, X.; Zou, J.; Toothaker, J. M.; Olaloye, O.; Santiago, E. G.; McCourt, B.; Mitsialis, V.; Presicce, P.; Kallapur, S. G.; Snapper, S. B.; Liu, J.-J.; Tseng, G.; Konnikova, L.; Liu, S.

10.1101/2024.08.12.607667 — bioinformatics — Posted on 2024-08-15

2804 Under Cover of Darkness: Refuge from Artificial Light at Night may Mitigate Risks to Stranded Seabirds

Brown, T. M.; Baker, K.; Wilhelm, S. I.; Burness, G.

10.1101/2024.08.12.607643 — animal behavior and cognition — Posted on 2024-08-15

2805 Dose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles

Yu, Y.; Spoth, K. A.; Colletta, M.; Nguyen, K. X.; Zeltmann, S. E.; Zhang, X. S.; Paraan, M.; Kopylov, M.; Dubbeldam, C.; Serwas, D.; Siems, H.; Muller, D. A.; Kourkoutis, L. F.

10.1101/2024.04.22.590491 — cell biology — Posted on 2024-08-15

2806 PIPETS: A statistically informed, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.

Furumo, Q.; Meyer, M. M.

10.1101/2024.03.18.585559 — bioinformatics — Posted on 2024-08-15

2807 EXPLANA: A user-friendly workflow for EXPLoratory ANAlysis and feature selection in cross-sectional and longitudinal microbiome studies

Fouquier, J.; Stanislawski, M.; O'Connor, J.; Scadden, A.; Lozupone, C.

10.1101/2024.03.20.585968 — bioinformatics — Posted on 2024-08-15

2808 Patch-walking: Coordinated multi-pipette patch clamp for efficiently finding synaptic connections

Yip, M. C.; Gonzalez, M. M.; Lewallen, C. F.; Landry, C. R.; Kolb, I.; Yang, B.; Stoy, W. M.; Fong, M.-f.; Rowan, M. J.; Boyden, E. S.; Forest, C. R.

10.1101/2024.03.30.587445 — bioengineering — Posted on 2024-08-15

2809 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences

Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.

10.1101/2024.03.05.583455 — microbiology — Posted on 2024-08-15

2810 A Novel Human Extravascular Monocyte Subset with Antiviral Functions Is Crucial for Resolving Lung Tissue Infection

Kenney, D. J.; O'Connell, A. K.; Tseng, A. E.; Turcinovic, J.; Sheahan, M. L.; Nitido, A. D.; Montanaro, P.; Gertje, H. P.; Ericsson, M.; Connor, J. H.; Vrbanac, V.; Crossland, N. A.; Harly, C.; Balazs, A. B.; Douam, F.

10.1101/2024.03.08.583965 — immunology — Posted on 2024-08-15

2811 Hidden hearing loss in a Charcot-Marie-Tooth type 1A mouse model

Cassinotti, L. R.; Ji, L.; Yuk, M. C.; Desai, A. S.; Cass, N. D.; Amir, Z. A.; Corfas, G.

10.1101/2023.12.14.571732 — neuroscience — Posted on 2024-08-15

2812 Noise robustness and metabolic load determine the principles of central dogma regulation

Lo, T. W.; Choi, H. J.; Huang, D.; Wiggins, P. A.

10.1101/2023.10.20.563172 — systems biology — Posted on 2024-08-15

2813 Genome sequence of the ornamental plant Digitalis purpurea reveals the molecular basis of flower color and morphology variation

Horz, J. M.; Wolff, K.; Friedhoff, R.; Pucker, B.

10.1101/2024.02.14.580303 — plant biology — Posted on 2024-08-15

2814 DNA methylation correlates with transcriptional noise in response to elevated pCO2 in the eastern oyster (Crassostrea virginica)

Venkataraman, Y. R.; Huffmyer, A. S.; White, S. J.; Downey-Wall, A.; Ashey, J.; Becker, D. M.; Bengtsson, Z.; Putnam, H. M.; Strand, E.; Rodriguez-Casariego, J. A.; Wanamaker, S. A.; Lotterhos, K. E.; Roberts, S.

10.1101/2024.04.04.588108 — physiology — Posted on 2024-08-15

2815 Deep-tissue spatial omics: imaging whole-embryo transcriptomics and subcellular structures at high spatial resolution

Gandin, V.; Kim, J.; Yang, L.-Z.; Lian, Y.; Kawase, T.; Hu, A.; Rokicki, K.; Fleishman, G.; Tillberg, P.; Aguilera Castrejon, A.; Stringer, C.; Preibisch, S.; Liu, Z. J.

10.1101/2024.05.17.594641 — developmental biology — Posted on 2024-08-15

2816 Multiomic analysis reveals developmental dynamics of the human heart in health and disease

Cranley, J.; Kanemaru, K.; Bayraktar, S.; Knight-Schrijver, V.; Pett, J. P.; Polanski, K.; Dabrowska, M.; Mulas, I.; Richardson, L.; Semprich, C.; Kapuge, R.; Perera, S.; He, X.; Ho, S. Y.; Yayon, N.; Tuck, L.; Roberts, K.; Palmer, J.; Davaapil, H.; Gambardella, L.; Patel, M.; Tyser, R.; Sinha, S.; Teichmann, S.

10.1101/2024.04.29.591736 — developmental biology — Posted on 2024-08-15

2817 Disease modification upon brief exposure to tofacitinib during chronic epilepsy.

Hoffman, O. R.; Koehler, J. L.; Espina, J. E. C.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.

10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-08-15

2818 Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy

Gligonov, I. A.; Enderlein, J.

10.1101/2024.04.06.588390 — biophysics — Posted on 2024-08-15

2819 Multiple Intermediates in the Detergent-Induced Fusion of Lipid Vesicles

Dresser, L. G.; Kunstmann-Olsen, C.; Conteduca, D.; Hofmair, C. M.; Smith, N.; Clark, L.; Johnson, S.; Penedo, C.; Leake, M. C.; Quinn, S. D.

10.1101/2023.09.21.558601 — biophysics — Posted on 2024-08-15

2820 SARS-CoV-2 NSP13 interacts with TEAD to suppress Hippo-YAP signaling

Meng, F.; Kim, J. H.; Tsai, C.-R.; Steimle, J.; Wang, J.; Shi, Y.; Li, R. G.; Xie, B.; Deshmukh, V.; Li, X.; Martin, J.

10.1101/2023.11.30.569413 — cell biology — Posted on 2024-08-15

2821 Visual statistical learning alters low-dimensional cortical architecture

Rowchan, K.; Gale, D. J.; Nick, Q.; Gallivan, J.; Wammes, J. D.

10.1101/2023.10.24.563271 — neuroscience — Posted on 2024-08-15

2822 Conserved role of the SERK-BIR module in development and immunity across land plants

Yan, Y.; Melluh, J.; Mecchia, M. A.; Jeon, H.-W.; Melkonian, K.; Holzberger, C.; Harzen, A.; Stolze, S. C.; Franzen, R.; Hirakawa, Y.; Delgado, A. I. C.; Nakagami, H.

10.1101/2024.08.14.607940 — plant biology — Posted on 2024-08-15

2823 Embracing native diversity to enhance maximum quantum efficiency of photosystem II in maize (Zea mays L.)

Urzinger, S.; Avramova, V.; Frey, M.; Urbany, C.; Scheuermann, D.; Presterl, T.; Reuscher, S.; Ernst, K.; Mayer, M.; Marcon, C.; Hochholdinger, F.; Brajkovic, S.; Ordas, B.; Westhoff, P.; Ouzunova, M.; Schoen, C.-C.

10.1101/2024.08.12.604917 — plant biology — Posted on 2024-08-15

2824 Territoriality and resource availability modulate the effect of conspecific encounters on the foraging behaviours of a mammalian predator

Clermont, J.; Dulude-de Broin, F.; Poulin, M.-P.; Berteaux, D.

10.1101/2024.08.14.607927 — ecology — Posted on 2024-08-15

2825 Predictive learning rules generate a cortical-like replay of probabilistic sensory experiences

Asabuki, T.; Fukai, T.

10.1101/2023.02.17.528958 — neuroscience — Posted on 2024-08-15

2826 A leaf-expressed TERMINAL FLOWER1 ortholog from coffee with alternate splice forms alters flowering time and inflorescence branching in Arabidopsis

Cardon, C.; Lesy, V.; Fust, C.; Ribeiro, T.; Hebb, O.; de Oliveira, R. R.; Minow, M.; Chalfun-Junior, A.; Colasanti, J.

10.1101/2024.08.14.607758 — plant biology — Posted on 2024-08-15

2827 A telosma mosaic virus-based vector for foreign gene expression and virus-induced gene silencing in the perennial woody vine, passion fruit (Passiflora edulis)

Wang, X.; Qin, L.; Shen, W.; Qiu, W.; Cui, H.; Dai, Z.

10.1101/2024.08.13.607796 — plant biology — Posted on 2024-08-15

2828 Infected grapevines are poor hosts but can serve as source of pathogen transmission for SLF

Islam, M. T.; Kudla-Williams, C.; Harner, A. D.; Centinari, M.; Rosa, C.

10.1101/2024.08.13.607612 — plant biology — Posted on 2024-08-15

2829 Increased chloroplast area in the rice bundle sheath through cell specific perturbation of brassinosteroid signalling

Cackett, L.; Luginbuehl, L. H.; Hendron, R.-W.; Plackett, A. R. G.; Stanley, S.; Kelly, S.; Hibberd, J. M.

10.1101/2024.08.14.607565 — plant biology — Posted on 2024-08-15

2830 Evolutionary Origins and Functional Diversification of Auxin Response Factors

Hernandez-Garcia, J.; Carrillo-Carrasco, V. P.; Rienstra, J.; Tanaka, K.; de Roij, M.; Dipp-Alvarez, M.; Freire-Rios, A.; Crespo Garcia, I.; Boer, R.; van den Berg, W.; Lindhoud, S.; Weijers, D.

10.1101/2024.08.14.607941 — plant biology — Posted on 2024-08-15

2831 Distinct Proline residues in hinge-regions of SYMRK generates a phosphocode for releasing Malectin-like-Domain to allow progress of rhizobia-legume symbiosis at epidermal-cortical barrier.

Chakrabarti, D.; Paul, A.; Bhattacharyya, S.; Das, S.; Molla, F.; Biswas, A.; DasGupta, M.

10.1101/2024.08.14.607956 — plant biology — Posted on 2024-08-15

2832 Performance of phenomic selection in rice: effects of population size and genotype-environment interactions on predictive ability

DE VERDAL, H.; Segura, V.; Pot, D.; Salas, N.; Garin, V.; Rakotoson, T.; Raboin, L.-M.; Vom Brocke, K.; Dusserre, J.; Castro Pacheco, S. A.; Grenier, C.

10.1101/2024.08.15.608050 — plant biology — Posted on 2024-08-15

2833 Differential induction of Medicago truncatula defence metabolites in response to rhizobial symbiosis and pea aphid infestation

Benjamin, G.; Pacoud, M.; Boutet, S.; Clement, G.; Brouquisse, R.; Gatti, J.-L.; POIRIE, M.; Frendo, P.

10.1101/2024.08.14.607928 — plant biology — Posted on 2024-08-15

2834 Iron homeostasis in the annual and perennial stem zones of Arabis alpina

Sergeeva, A.; Mai, H.-J.; Bauer, P.

10.1101/2024.08.13.607737 — plant biology — Posted on 2024-08-15

2835 Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images

ZHAO, W.; LIANG, Z.; HUANG, X.; Huang, Y.; Yu, L.

10.1101/2024.02.17.580852 — bioengineering — Posted on 2024-08-15

2836 European freshwater macroinvertebrate richness and abundance: alternative analyses and new findings

Demars, B. O. L.

10.1101/2024.08.13.607735 — ecology — Posted on 2024-08-15

2837 Larger diet particle sizes cause crickets to grow faster with no effect on final body size

Muzzatti, M. J.; Kong, J. D.; McColville, E. R.; Brzezinski, H.; Stabile, C. C.; MacMillan, H. A.; Bertram, S. M.

10.1101/2024.08.13.607817 — ecology — Posted on 2024-08-15

2838 Monsoonal climate and asymmetric heating facilitate the slope-aspect to influence landscape-scale tree structure in the Western Ghats, India

Maheshwori, D.; Managave, S.; Jathar, G.; Davande, S.

10.1101/2024.08.13.607866 — ecology — Posted on 2024-08-15

2839 Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion

Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Ohno, T.; Yokoi, N.; Yamada, Y.; Suzuki, A.

10.1101/2024.08.15.608033 — cell biology — Posted on 2024-08-15

2840 Postsynaptic frequency filters shaped by the interplay of synaptic short-term plasticity and cellular time scales

Mondal, Y.; Villanueva Benito, G.; Pena, R. F.; Rotstein, H. G.

10.1101/2023.07.02.547439 — neuroscience — Posted on 2024-08-15

2841 Age-Related Cerebral Ventriculomegaly occurs in Patients with Primary Ciliary Dyskinesia

Eisenhuth, F. E.; Agbonze, J. E.; Groh, A. M. R.; Rudko, D. A.; Klostranec, J.; Stratton, J. A.; Shapiro, A. J.

10.1101/2024.08.12.607515 — neuroscience — Posted on 2024-08-15

2842 qPRF: A system to accelerate population receptive field decoding

Waz, S.; Wang, Y.; Lu, Z.-L.

10.1101/2024.08.13.607805 — neuroscience — Posted on 2024-08-15

2843 Cortical and behavioural tracking of rhythm in music: Effects of pitch predictability, enjoyment, and expertise

Keitel, A.; Pelofi, C.; Guan, X.; Watson, E.; Wight, L.; Allen, S.; Mencke, I.; Keitel, C.; Rimmele, J. M.

10.1101/2023.10.15.562351 — neuroscience — Posted on 2024-08-15

2844 Muscarinic receptors mediate motivation via preparatory neural activity in humans

Grogan, J. P.; Raemaekers, M.; van Swieten, M. M. H.; Green, A. L.; Gillies, M. J.; Manohar, S. G.

10.1101/2021.07.28.454154 — neuroscience — Posted on 2024-08-15

2845 Field conditions greatly modify a major growth-defense tradeoff in Arabidopsis thaliana

Lundberg, D. S.; Kersten, S.; Mehmetoglu Boz, E.; Pramoj Na Ayutthaya, P.; Zhu, W.; Poersch, K.; Yuan, W.; Swartz, S.; Müller, D.; Bezrukov, I.; Harvest Team, ; Weigel, D.

10.1101/2024.08.15.607984 — plant biology — Posted on 2024-08-15

2846 The splicing factor kinase SRPK1 is a therapeutic target for Peripheral Vascular Disease

Bhalla, S. R.; Wahid, M.; Amartey, J.; Riu, F.; Gao, Y.; Agrawal, J.; Lynch, A. P.; Machado, M. J.; Hawtrey, T.; Kikuchi, R.; Green, K. R.; Teboul, L.; Allen, C.; Blackley, Z.; Rajaji, K.; Marsden, D.; Batson, J.; Harper, S. J.; Oltean, S.; Amoaku, W.; Benest, A. V.; Morris, J. C.; Braithwaite, B.; Bates, D. O.

10.1101/2024.04.17.589996 — physiology — Posted on 2024-08-15

2847 Intestinal LKB1 loss drives a pre-malignant program along the serrated cancer pathway

Plugge, S. F.; Ma, H.; van der Vaart, J. Y.; Sprangers, J.; Morsink, F. H. M.; Xanthakis, D.; Jamieson, C.; Keijzer, A. R.; Margaritis, T.; Candelli, T.; Straver, R.; de Ridder, J.; Holstege, F. C. P.; de Leng, W. W. J.; Offerhaus, G. J. A.; Merenda, A.; Maurice, M. M.

10.1101/2023.07.17.548873 — cancer biology — Posted on 2024-08-15

2848 scCancerExplorer: a comprehensive database for interactively exploring single-cell multi-omics data of human pan-cancer

Huang, C.; Liu, Z.; Guo, Y.; Wang, W.; Yuan, Z.; Guan, Y.; Pan, D.; Hu, Z.; Sun, L.; Fu, Z.; Bian, S.

10.1101/2024.06.24.600356 — cancer biology — Posted on 2024-08-15

2849 EMhub: a web platform for data management and on-the-fly processing in scientific facilities

De la Rosa Trevin, J. M.; Sharov, G.; Fleischmann, S.; Morado, D.; Bollinger, J. C.; Miller, D. J.; Terry, D. S.; Blanchard, S. C.; Fernandez, I. S.; Carroni, M. S.

10.1101/2024.08.12.607607 — biophysics — Posted on 2024-08-15

2850 Statistical estimation of sparsity and efficiency for molecular codes

Fung, J. H.; Carriere, M.; Blumberg, A. J.

10.1101/2024.08.13.607773 — bioinformatics — Posted on 2024-08-15

2851 Multi-strategies embedded framework for neoantigen vaccine maturation

Zhang, G.; Fu, Y.; Chan, K. C.; Jin, R.; Yang, Y.; Zhou, R.

10.1101/2024.08.14.607669 — bioinformatics — Posted on 2024-08-15

2852 Changes in Proteome Profiles Linked to Hormonal Contraceptive Use Among African American Women with untreated high blood pressure

DeRoo, L.; Abbas, M.; Goodney, G.; Gaye, A.

10.1101/2024.08.12.607634 — genomics — Posted on 2024-08-15

2853 Whole Genome Sequencing Analysis of a Recent Multi-Drug Resistant Shigella sonnei Outbreak Among Tunisian Children

Ferjani, S.; Kanzari, L.; Hamzaoui, Z.; Jomni, L.; Ferjani, A.; Fakhfekh, A.; Bahri, O.; Achour, W.; Zribi, M.; Trabelsi, S.; Alya, N. B.; Itani, D.; Bouwazra, S.; Foster-Nyarko, E.; Boubaker, I. B. B.

10.1101/2024.08.12.607540 — genomics — Posted on 2024-08-15

2854 Looking for unique signals of human expansion from Africa: Beyond diversity

Cenac, Z.

10.1101/2024.08.13.607798 — evolutionary biology — Posted on 2024-08-15

2855 Divergent realized ecological niches of sister species of the Antarctic amphipod genus Charcotia

Aerts, D. N.; Kolder, A.; Lepoint, G.; Michel, L. N.; Schön, I.

10.1101/2024.08.14.607880 — ecology — Posted on 2024-08-15

2856 Farmyard Mulching in Regenerative Agriculture Enhances Saprotrophs and Concomitantly Reduces Pathogenic Fungal Genera

Naresh, P.; Singh, I.

10.1101/2024.08.14.607896 — ecology — Posted on 2024-08-15

2857 Marbled Murrelet Habitat Suitability in Redwood Timberlands of Northern Coastal California Utilizing LiDAR-Derived Individual Tree Metrics

Lamphear, D. W.; Hamm, K.; Early, D.; McDonald, T. W.

10.1101/2024.08.13.607789 — ecology — Posted on 2024-08-15

2858 Stable isotope composition of Antarctic marine mammals collected at the turn of the 20th century: assessing the baseline for long-term changes in the marine ecosystem

Genelt-Yanovskiy, E.; Genelt-Yanovskaya, A.; Fontanals-Coll, M.; Yamoah, K. A.; Craig, O.; Sabin, R.; Scourse, J.

10.1101/2024.08.13.607746 — ecology — Posted on 2024-08-15

2859 Variable responses of alpine-plant communities to warming and loss of dominant species

Marraffini, M. L.; Classen, A. T.; Sanders, N. J.; Sundquist, M. k.; Deslippe, J. R.; He, J. S.; McLaren, J. R.; Rixen, C.; Wipf, S.; Chisholm, C.; Prager, C.; Stouffer, D. B.

10.1101/2024.08.13.604445 — ecology — Posted on 2024-08-15

2860 Navigating the Landscape of Fear

Gee, M.; Gonzalez-Granda, N.; Joshi, S.; Rudrapatna, N.; Somalwar, A.; Ellner, S.; Vladimirsky, A.

10.1101/2024.08.15.608007 — ecology — Posted on 2024-08-15

2861 Long-term non-trophic effects of large herbivores on plant diversity are underestimated

Chen, Q.; Bakker, J.; Alberti, J.; Bakker, E. S.; Smit, C.; Olff, H.

10.1101/2024.08.13.607836 — ecology — Posted on 2024-08-15

2862 Heterogeny in cages: Age-structure and timing of attractant availability impacts fertile egg production in the black soldier fly, Hermetia illucens

Lemke, N. B.; Li, C.; Dickerson, A.; Salazar, D. A.; Rollinson, L. N.; Mendoza, J. E.; Miranda, C. D.; Crawford, S.; Tomberlin, J. K.

10.1101/2024.08.13.607807 — ecology — Posted on 2024-08-15

2863 Population dynamics in spatial suppression gene drive models and the effect of resistance, density dependence, and life history

Zhang, X.; Sun, W.; Kim, I. K.; Messer, P. W.; Champer, J.

10.1101/2024.08.14.607913 — ecology — Posted on 2024-08-15

2864 A test for microbiome-mediated rescue via host phenotypic plasticity in Daphnia

Shahmohamadloo, R. S.; Gabidulin, A. R.; Andrews, E. R.; Fryxell, J. M.; Rudman, S. M.

10.1101/2024.08.14.607994 — ecology — Posted on 2024-08-15

2865 Human footprint and forest disturbance reduce space use of brown bears across Europe.

Hertel, A. G.; Parres, A.; Frank, S. C.; Renaud, J.; Selva, N.; Zedrosser, A.; Balkenhol, N.; Maiorano, L.; Fedorca, A.; Dutta, T.; Bogdanovi_, N.; Bragalanti, N.; Chiriac, S.; Cirovic, D.; Ciucci, P.; Domokos, C.; Fedorca, M.; Filacorda, S.; Findo, S.; Groff, C.; de Gabriel Hernando, M.; Huber, D.; Ionescu, G.; Jerina, K.; Karamanlidis, A. A.; Kindberg, J.; Kojola, I.; Mertzanis, Y.; Palazon, S.; Pop, M. I.; Psaralexi, M.; Quenette, P. Y.; Sergiel, A.; Skuban, M.; Zlatanova, D.; Zwijacz-Kozica, T.; De Barba, M.

10.1101/2024.08.14.607538 — ecology — Posted on 2024-08-15

2866 An ecological, phenotypic and genomic survey of duckweeds with their associated aquatic environments in the United Kingdom

Smith, K. E.; Cowan, L.; Flis, P.; Moore, C.; Heatley, M.; Robles-Zazueta, C. A.; Lee, A.; Yant, L.

10.1101/2024.08.14.607898 — ecology — Posted on 2024-08-15

2867 Graphical Representation of Landscape Heterogeneity Identification through Unsupervised Acoustic Analysis

Guerrero, M. J.; Sanchez-Giraldo, C.; Martinez, V.; Uribe, C. A.; Isaza, C.

10.1101/2024.08.12.607639 — ecology — Posted on 2024-08-15

2868 Rapid Parallel Visual Presentation Provides a New Perspective on Relative Clause Processing in Mandarin Chinese

Dunagan, D.; McLendon, J.; Jordan, T.; Chacon, D. A.

10.1101/2024.08.13.607840 — neuroscience — Posted on 2024-08-15

2869 Pandora: A Tool to Estimate Dimensionality Reduction Stability of Genotype Data

Haag, J.; Jordan, A. I.; Stamatakis, A.

10.1101/2024.03.14.584962 — bioinformatics — Posted on 2024-08-15

2870 Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells

Capera, J.; Jainarayanan, A. K.; Valvo, S.; Chen, L.; Quayle, S. N.; Moniz, R. J.; Suri, A.; Dustin, M.

10.1101/2024.08.13.607831 — immunology — Posted on 2024-08-15

2871 A versatile correlative light and electron microscopy protocol for human brain and other biological models

Shafiei, N.; Stahli, D.; Burger, D.; Di Fabrizio, M.; Van den Heuvel, L.; Daraspe, J.; Boing, C.; Shahmoradian, S. H.; van de Berg, W. D. J.; Genoud, C.; Stahlberg, H.; Lewis, A.

10.1101/2024.06.11.598271 — neuroscience — Posted on 2024-08-15

2872 Next generation AMA1-based plasmids for enhanced heterologous expression in filamentous fungi

Roux, I.; Woodcraft, C.; Sbaraini, N.; Pepper, A.; Wong, E.; Bracegirdle, J.; Chooi, Y.-H.

10.1101/2024.06.01.596972 — synthetic biology — Posted on 2024-08-15

2873 ImmunoCellCycle-ID: A high-precision immunofluorescence-based method for cell cycle identification

Chen, Y.-L.; Chen, Y.-C.; Suzuki, A.

10.1101/2024.08.14.607961 — cell biology — Posted on 2024-08-15

2874 Live imaging in zebrafish reveals tissue-specific strategies for amoeboid migration

Robertson, T. F.; Schrope, J.; Zwick, Z.; Rindy, J. K.; Horn, A.; Huttenlocher, A.

10.1101/2024.08.14.607647 — cell biology — Posted on 2024-08-15

2875 Structural Analyses of a GABARAP~ATG3 Conjugate Uncover a Novel Non-covalent Ubl-E2 Backside Interaction

Ohashi, K.; Otomo, T.

10.1101/2024.08.14.607425 — biochemistry — Posted on 2024-08-15

2876 Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade

Rancilhac, L.; de Souza, S. G.; Lukhele, S. M.; Sebastianelli, M.; Ogolowa, B. O.; Moysi, M.; Nikiforou, C.; Asfaw, T.; Downs, C. T.; Brelsford, A.; vonHoldt, B. M.; Kirschel, A. N. G.

10.1101/2024.08.13.607717 — evolutionary biology — Posted on 2024-08-15

2877 Dysregulated Airway Host Defense in Hyper IgE Syndrome due to STAT3 Mutations

Sun, L.; Walls, S. A.; Dang, H.; Quinney, N. L.; Sears, P. R.; Sadritabrizi, T.; Hasegawa, K.; Okuda, K.; Asakura, T.; Chang, X.; Zheng, M.; Mikami, Y.; Dizmond, F. U.; Danilova, D.; Zhou, L.; Deshmukh, A.; Cholon, D. M.; Radicioni, G.; Rogers, T. D.; Kissner, W. J.; Markovetz, M. R.; Guhr Lee, T. N.; Gutay, M. I.; Esther, C. R.; Chua, M.; Grubb, B. R.; Ehre, C.; Kesimer, M.; Hill, D. B.; Ostrowski, L. E.; Button, B.; Gentzsch, M.; Robinson, C.; Olivier, K. N.; Freeman, A. F.; Randell, S. H.; O'Neal, W. K.; Boucher, R. C.; Chen, G.

10.1101/2024.08.14.607930 — cell biology — Posted on 2024-08-15

2878 Quantifying anti-DUX4 therapy for facioscapulohumeral muscular dystrophy

Cowley, M. V.; Zammit, P. S.; Banerji, C. R. S.

10.1101/2024.08.14.607973 — cell biology — Posted on 2024-08-15

2879 NOK promotes tumorigenesis through coordinating epidermal growth factor receptor to boost the downstream signaling in breast cancer

Wang, Y.; Zhang, B.; He, C.; Tian, B.; Liu, S.; Li, J.; Wang, J.; Yang, S.; Zhu, B.; Wang, X.; Chang, Z.; Cao, C.

10.1101/2024.08.14.608018 — cell biology — Posted on 2024-08-15

2880 alpha-Actinin-3 deficiency protects from the effects of acute cold exposure through altered skeletal muscle Ca2+ and OXPHOS signaling.

Houweling, P. J.; Tiong, C. F.; Kiriaev, L.; Diaz-Pena, R.; Albers, P. K.; Wood, H.; Wyckelsma, V.; Stait, T.; Venckunas, T.; Valenzuela, P.; Castillo-Garcia, A.; Brazaitis, M.; Berman, Y.; Seto, J. T.; Westerblad, H.; Lek, M.; Thorburn, D.; Lucia, A.; Head, S.; North, K. N.

10.1101/2024.08.14.605938 — cell biology — Posted on 2024-08-15

2881 Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence

Sanchez-Martinez, R.; Arani, A.; Krupovic, M.; Weitz, J. S.; Santos, F.; Anton, J.

10.1101/2024.07.30.605759 — microbiology — Posted on 2024-08-15

2882 Hierarchical Working Memory and a New Magic Number

Zhong, W.; Katkov, M.; Tsodyks, M.

10.1101/2024.08.14.607952 — neuroscience — Posted on 2024-08-15

2883 Mediodorsal thalamic nucleus mediates resistance to ethanol through Cav3.1 T-type Ca2+ regulation of neural activity

Latchoumane, c.-f. V.; Lee, J.-H.; Kim, S.-W.; Kim, J.; Shin, H.-S.

10.1101/2023.09.25.558585 — neuroscience — Posted on 2024-08-15

2884 Common marmosets use body posture as multi-functional signal to solicit, maintain, and modify social play

Adriaense, J. E. C.; Ringen, E.; Ohashi, A.; Burkart, J.

10.1101/2024.08.14.607991 — animal behavior and cognition — Posted on 2024-08-15

2885 Phylogenetic proximity drives temporal succession of marine giant viruses in a five-year metagenomic time-series

Laperriere, S. M.; Minch, B.; Weissman, J.; Hou, S.; Yeh, Y.-C.; Ignacio-Espinoza, J. C. L.; Ahlgren, N. A.; Moniruzzaman, M.; Fuhrman, J. A.

10.1101/2024.08.12.607631 — ecology — Posted on 2024-08-15

2886 Microbiota-induced plastic T cells enhance immune control of antigen-sharing tumors

Najar, T. A.; Hao, Y.; Hao, Y.; Romero-Meza, G.; Dolynuk, A.; Littman, D. R.

10.1101/2024.08.12.607605 — immunology — Posted on 2024-08-15

2887 Leveraging Multi-Echo EPI to Enhance BOLD Sensitivity in Task-based Olfactory fMRI

Zhao, L. S.; Raithel, C. U.; Tisdall, D.; Detre, J. A.; Gottfried, J. A.

10.1101/2024.01.15.575530 — neuroscience — Posted on 2024-08-15

2888 Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes

Arizanovska, D.; Dallera, C. A.; Folorunso, O. O.; Bush, G. F.; Frye, J. B.; Doyle, K. P.; Jagid, J. R.; Monaco, B. A.; Cordeiro, J. G.; Atkins, C. M.; Griswold, A. J.; Liebl, D. J.

10.1101/2024.08.13.607610 — neuroscience — Posted on 2024-08-15

2889 Cell type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development

Yim, K. M.; Baumgartner, M.; Krenzer, M.; Larios, M. F. R.; Hill-Teran, G.; Nottoli, T.; Muhle, R. A.; Noonan, J. P.

10.1101/2024.08.14.608000 — neuroscience — Posted on 2024-08-15

2890 Peripubertal antagonism of corticotropin-releasing factor receptor 1 results in sustained, sex-specific changes in behavioral plasticity and the transcriptomic profile of the amygdala

Martz, J.; Shelton, M. A.; Langen, T. J.; Srinivasan, S.; Seney, M. L.; Kentner, A. C.

10.1101/2024.08.14.607957 — neuroscience — Posted on 2024-08-15

2891 Neurophysiology of effortful listening: Decoupling motivational modulation from task demands

Kraus, F.; Ross, B.; Herrmann, B.; Obleser, J.

10.1101/2024.03.27.587038 — neuroscience — Posted on 2024-08-15

2892 HLA polymorphism impacts immune response to neoepitopes and survival in APOBEC-mutated cancers

Borzooee, F.; Heravi-Moussavi, A.; Larijani, M.

10.1101/2024.08.07.607038 — cancer biology — Posted on 2024-08-15

2893 Transcriptomic signatures of mouse ovarian aging and estropausal transition at single cell resolution

Wang, X.; Yang, J.; Jin, C.; Wang, X.; Contreras, D.; Devos, M.; Suh, Y.

10.1101/2024.08.12.607592 — bioinformatics — Posted on 2024-08-15

2894 End-to-end simulation of nanopore sequencing signals with feed-forward transformers

Beslic, D.; Kucklick, M.; Engelmann, S.; Fuchs, S.; Renard, B. Y.; Koerber, N.

10.1101/2024.08.12.607296 — bioinformatics — Posted on 2024-08-15

2895 Heme binding causes structural rearrangements in HRI to inhibit activation via autophosphorylation

Kanta, S.; Vinciauskaite, V.; Neill, G.; Muqit, M. M. K.; Masson, G. R.

10.1101/2024.08.14.607626 — biochemistry — Posted on 2024-08-14

2896 Paradoxical Activation of GCN2 by ATP-competitive inhibitors via allosteric activation and autophosphorylation

Neill, G.; Vinciauskaite, V.; Paul, M.; Gilley, R.; Cook, S. J.; Masson, G. R.

10.1101/2024.08.14.606984 — biochemistry — Posted on 2024-08-15

2897 Ungulate substrate use in fauna passages

Helldin, J. O.; Niemi, M.

10.1101/2024.02.08.579517 — animal behavior and cognition — Posted on 2024-08-15

2898 Cephalopod Sex Determination and its Ancient Evolutionary Origin

Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.

10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-08-14

2899 Allocating Limited Surveillance Effort for Outbreak Detection of Endemic Foot and Mouth Disease

Greiner, A.; Herrera-Diestra, J. L.; Tildesley, M.; Shea, K.; Ferrari, M.

10.1101/2024.08.12.607549 — ecology — Posted on 2024-08-14

2900 Extracellular ISG15 triggers ISGylation via a type-I interferon independent non-canonical mechanism to regulate host response during virus infection

Miller, L. G.; Chiok, K.; Mariasoosai, C.; Mohanty, I.; Pandit, S.; Deol, P.; Mehari, L.; Teng, M. N.; Haas, A. L.; Natesan, S.; Miura, T. A.; Bose, S.

10.1101/2024.07.05.602290 — immunology — Posted on 2024-08-14

2901 Inhibitory neurons marked by a connectivity molecule regulate memory precision

Tunon-Ortiz, A. B. N.; Trankner, D.; Brockway, S. N.; Raines, O. K.; Mahnke, A.; Grega, M.; Zelikowsky, M.; Williams, M. E.

10.1101/2024.07.05.602304 — neuroscience — Posted on 2024-08-14

2902 Computational basis of hierarchical and counterfactual information processing

Ramadan, M.; Tang, C.; Watters, N.; Jazayeri, M.

10.1101/2024.01.30.578076 — neuroscience — Posted on 2024-08-14

2903 Viral delivery of an RNA-guided genome editor for transgene-free germline editing in Arabidopsis

Weiss, T.; Kamalu, M.; Shi, H.; Li, Z.; Amerasekera, J.; Zhong, Z.; Adler, B. A.; Song, M.; Vohra, K.; Wirnowski, G.; Chitkara, S.; Ambrose, C.; Steinmetz, N.; Sridharan, A.; Sahagun, D.; Banfield, J.; Doudna, J.; Jacobsen, S. E.

10.1101/2024.07.17.603964 — plant biology — Posted on 2024-08-14

2904 Enzyme family-centred approach identifies helicases as recurrent hemizygous tumour suppressor genes

Sorensen, C. S.; Weischenfeldt, J.; Favero, F.; Mardin, B.; Li, X.; Olsen, A.; Kashyap, K.; Vossgrone, K.; Rodriguez, G.

10.1101/2024.08.13.607019 — cancer biology — Posted on 2024-08-14

2905 Submolecular-scale Hairpin DNA Folding Dynamics Studied by High-Speed AFM with Optical Tweezers

Umeda, K.; Yamanaka, S.; Imamura, M.; Nagae, F.; Fukuda, S.; Watanabe, H.; Uchihashi, T.; Takada, S.; Ando, T.

10.1101/2024.08.14.605043 — biophysics — Posted on 2024-08-14

2906 Predicting microscale beat patterns from nanoscale chemomechanics in eukaryotic flagella

Cass, J. F.; Bloomfield-Gadelha, H.

10.1101/2024.08.14.607876 — biophysics — Posted on 2024-08-14

2907 Unveiling Mechanistic and Structural Insights of EstS1 Esterase: A Potent Broad-Spectrum Phthalate Diester Degrading Enzyme

VERMA, S.; Choudhary, S.; Kamble, A. K.; Mahto, J. K.; Vamsi K, A. K.; Mishra, I.; Prakash, V. B.; Sircar, D.; Tomar, S.; Sharma, A. K.; Singla, J.; KUMAR, P.

10.1101/2024.08.14.607922 — biophysics — Posted on 2024-08-14

2908 Identification of In Vivo Internalizing Cardiac-Specific RNA Aptamers

Narayan, C.; Lin, L.-H.; Barros, M. B.; Gilbert, T. C.; Brown, C. R.; Reddin, D.; London, B.; Chen, Y.; Wilson, M. E.; Streeter, J.; Thiel, W.

10.1101/2024.08.13.607054 — bioengineering — Posted on 2024-08-14

2909 PURE-seq identifies Egr1 as a Potential Master Regulator in Murine Aging by Sequencing Long-Term Hematopoietic Stem Cells

Pan, S.; Chang, K.-C.; Fernandez-Maestre, I.; Haver, S. V.; Wereski, M. G.; Bowman, R. L.; Levine, R. L.; Abate, A. R.

10.1101/2024.08.12.607664 — bioengineering — Posted on 2024-08-14

2910 Heme binding causes structural rearrangements in HRI to inhibit activation via autophosphorylation

Masson, G. R.; Kanta, S.; Vinciauskaite, V.; Neill, G.; Muqit, M. M. K.

10.1101/2024.08.14.607626 — biochemistry — Posted on 2024-08-14

2911 Bibacillin 1: A two-component lantibiotic from Bacillus thuringiensis

Moreira, R.; Yang, Y.; Luo, Y.; Gilmore, M. S.; van der Donk, W.

10.1101/2024.08.13.607848 — biochemistry — Posted on 2024-08-14

2912 Changing expression system alters oligomerization and proinflammatory activity of recombinant human S100A9

Chisholm, L. O.; Jeon, C. K.; Prell, J. S.; Harms, M. J.

10.1101/2024.08.14.608001 — biochemistry — Posted on 2024-08-14

2913 The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-alpha-inhibitor regulate crosslinking of the hyaluronan matrix

Shah, A.; Zhang, X.; Snee, M.; Lockhart-Cairns, M. P.; Levy, C. W.; Jowitt, T. A.; Birchenough, H. L.; Dean, L.; Collins, R.; Dodd, R. J.; Roberts, A. R. E.; Enghild, J. J.; Mantovani, A.; Fontana, J.; Baldock, C.; Inforzato, A.; Richter, R. P.; Day, A. J.

10.1101/2024.08.14.607909 — biochemistry — Posted on 2024-08-14

2914 DNA damage-associated protein co-expression network in cardiomyocytes informs on tolerance to genetic variation and disease

Johnson, O. D.; Paul, S.; Gutierrez, J. A.; Russell, W. K.; Ward, M. C.

10.1101/2024.08.14.607863 — genetics — Posted on 2024-08-14

2915 Introgression across narrow contact zones shapes the genomic landscape of phylogenetic variation in an African bird clade

Rancilhac, L.; de Souza, S. G.; Lukhele, S. M.; Sebastianelli, M.; Ogolowa, B. O.; Moysi, M.; Nikiforou, C.; Asfaw, T.; Downs, C. T.; Brelsford, A.; vonHoldt, B. M.; Kirschel, A. N. G.

10.1101/2024.08.13.607717 — evolutionary biology — Posted on 2024-08-14

2916 Recent genetic drift in the co-diversified gut bacterial symbionts of laboratory mice

Sprockett, D. D.; Dillard, B. A.; Landers, A. A.; Sanders, J. G.; Moeller, A. H.

10.1101/2024.08.14.607958 — evolutionary biology — Posted on 2024-08-14

2917 Discovering methylated DNA motifs in bacterial nanopore sequencing data with MIJAMP

Tidwell, A. K.; Faust, E.; Eckert, C. A.; Guss, A. M.; Alexander, W.

10.1101/2024.08.14.607972 — molecular biology — Posted on 2024-08-14

2918 Genome-wide screen overexpressing mycobacteriophage Amelie genes identifies multiple inhibitors of mycobacterial growth

Tafoya, C.; Ching, B.; Garcia, E. P.; Lee, A.; Acevedo, M.; Bass, K.; Chau, E.; Lin, H.; Mamora, K.; Reeves, M.; Vaca, M.; van Iderstein, W.; Velasco, L.; Williams, V.; Yonemoto, G.; Yonemoto, T.; Heller, D. M.; Diaz, A.

10.1101/2024.08.14.607960 — microbiology — Posted on 2024-08-14

2919 Inferring replication states of bacteria and viruses in enrichment cultures via long-read sequencing

Simon, S. A.; Soares, A.; Bornemann, T. L. V.; Lange, A.; Griesdorn, L.; Fuentes, A.; Dieckmann, M.; Krok, B.; Ruff, S. E.; Hugler, M.; Moraru, C.; Probst, A. J.

10.1101/2024.08.14.607915 — microbiology — Posted on 2024-08-14

2920 Dual CRISPRi-Seq for genome-wide genetic interaction studies identifies key genes involved in the pneumococcal cell cycle

Denereaz, J.; Eray, E.; Jana, B.; de Bakker, V.; Todor, H.; van Opijnen, T.; Liu, X.; Veening, J.-W.

10.1101/2024.08.14.607739 — microbiology — Posted on 2024-08-14

2921 New viruses infecting hyperthermophilic bacterium Thermus thermophilus

Kolesnik, M.; Pavlov, C.; Demkina, A.; Samolygo, A.; Karneyeva, K.; Trofimova, A.; Sokolova, O. S.; Moiseenko, A. V.; Kirsanova, M.; Severinov, K.

10.1101/2024.08.14.607894 — microbiology — Posted on 2024-08-14

2922 Machine learning uncovers gene families impacting oxidative stress resistance across yeasts

Aranguiz, K.; Horianopoulos, L. C.; Elkin, L.; Aba, K. S.; Wrobel, R. L.; Shiu, S.-H.; Rokas, A.; Hittinger, C. T.

10.1101/2024.08.14.607963 — microbiology — Posted on 2024-08-14

2923 Kir6.1, a component of an ATP-sensitive potassium channel, regulates natural killer cell development

Samper, N.; Haroardottir, L.; Depierreux, D. M.; Song, S. C.; Nakazawa, A.; Gando, I.; Nakamura, T. Y.; Sharkey, A. M.; Nowosad, C. R.; Feske, S.; Colucci, F.; Coetzee, W. A.

10.1101/2024.08.14.608003 — immunology — Posted on 2024-08-14

2924 Protein Carrier AAV

Hoffmann, M. D.; Sorensen, R.; Extross, A.; He, Y.; Schmidt, D.

10.1101/2024.08.14.607995 — synthetic biology — Posted on 2024-08-14

2925 Paradoxical Activation of GCN2 by ATP-competitive inhibitors via allosteric activation and autophosphorylation

Masson, G. R.; Neill, G.; Vinciauskaite, V.; Paul, M.; Gilley, R.; Cook, S. J.

10.1101/2024.08.14.606984 — biochemistry — Posted on 2024-08-14

2926 Torsional Twist of the SARS-CoV and SARS-CoV-2 SUD-N and SUD-M domains

Rosas-Lemus, M.; Minasov, G.; Brunzelle, J. S.; Taha, T. Y.; Lemak, S.; Yin, S.; Shuvalova, L.; Rosecrans, J.; Khanna, K.; Seifert, H. S.; Savchenko, A.; Stogios, P. J.; Ott, M.; Satchell, K. J.

10.1101/2024.08.13.607777 — microbiology — Posted on 2024-08-14

2927 Surfactin facilitates the establishment of Bacillus subtilis in synthetic communities

Lozano-Andrade, C. N.; Dinesen, C.; Wibowo, M.; Arenos Bach, N.; Hesselberg-Thomsen, V.; Jarmusch, S. A.; Strube, M. L.; Kovacs, A. T.

10.1101/2024.08.14.607878 — microbiology — Posted on 2024-08-14

2928 Distinct bacterial and protist plankton diversity dynamics uncovered through DNA-based monitoring in the Baltic Sea area

Jurdzinski, K. T.; Latz, M. A.; Torstensson, A.; Brugel, S.; Hedblom, M.; Hu, Y. O. O.; Lindh, M.; Andersson, A.; Karlson, B.; Andersson, A. F.

10.1101/2024.08.14.607742 — microbiology — Posted on 2024-08-14

2929 WITHDRAWN: Multiplane Mesoscope reveals distinct cortical interactions following expectation violations

Orlova, N.; Najafi, F.; Tsyboulski, D.; Seid, S.; Kivikas, S.; Kato, I.; Griffin, F.; Leon, A.; L'Heureux, Q.; North, K.; Swapp, J.; Nayan, C.; Hancock, N.; Ahmed, R.; Gelfand, E.; Cho, A.; Mace, K.; Howard, R.; Casal, L.; Lambert, S.; Lee, E. K.; Caldejon, S.; Waughman, X.; Williford, A.; Garrett, M.; Ollerenshaw, D.; Olsen, S. R.; Groblewski, P.; Saggau, P.; Lecoq, J.

10.1101/2020.10.06.328294 — neuroscience — Posted on 2024-08-14

2930 Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation

Chen, L.; Chehade, H. D.; Chu, H.-Y.

10.1101/2024.07.24.604995 — neuroscience — Posted on 2024-08-14

2931 Inhibitory circuits generate rhythms for leg movements during Drosophila grooming

Syed, D. S.; Ravbar, P.; Simpson, J. H.

10.1101/2024.06.05.597468 — neuroscience — Posted on 2024-08-14

2932 Opto-CLIP reveals dynamic FMRP regulation of mRNAs upon CA1 neuronal activation

Singer, R. A.; Rajchin, V.; Park, K.; Heintz, N.; Darnell, R. B.

10.1101/2024.08.13.607210 — neuroscience — Posted on 2024-08-14

2933 Spatially organized striatal neuromodulator release encodes trajectory errors

Brown, E. H.; Zi, Y.; Vu, M.-A. T.; Bouabid, S.; Lindsey, J.; Godfrey-Nwachukwu, C.; Attarwala, A.; Litwin-Kumar, A.; DePasquale, B.; Howe, M.

10.1101/2024.08.13.607797 — neuroscience — Posted on 2024-08-14

2934 Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

Osorio, D.; Shahrouzi, P.; Tekpli, X.; Kristensen, V. N.; Kuijjer, M. L.

10.1101/2022.03.31.486602 — bioinformatics — Posted on 2024-08-14

2935 Seq2Topt: a sequence-based deep learning predictor of enzyme optimal temperature

Qiu, S.; Hu, B.; Zhao, J.; Xu, W.; Yang, A.

10.1101/2024.08.12.607600 — bioinformatics — Posted on 2024-08-14

2936 Risking your Tail: Modeling Individual Differences in Risk-sensitive Exploration using Bayes Adaptive Markov Decision Processes

Shen, T.; Dayan, P.

10.1101/2024.01.07.574574 — animal behavior and cognition — Posted on 2024-08-14

2937 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.

Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.

10.1101/2024.03.22.584691 — genetics — Posted on 2024-08-14

2938 Dynamic Wt1 expression in the gastrulation-stage mouse embryo specifies vascular and visceral smooth muscle cell fate independently from mesothelial fate.

Alsukari, S. H.; Ng, H. T.; Lang, L.; Lunn, S.; Beglinger, S.; Carr, L.; Boyes, M.; Turner, D. A.; Wilm, B.

10.1101/2024.08.08.607207 — developmental biology — Posted on 2024-08-14

2939 Comparative genomics reveals intra and inter species variation in the pathogenic fungus Batrachochytrium dendrobatidis

Yacoub, M. N.; Stajich, J. E.

10.1101/2024.01.24.576925 — microbiology — Posted on 2024-08-14

2940 Neural population dynamics underlying evidence accumulation in multiple rat brain regions

DePasquale, B.; Pillow, J. W.; Brody, C.

10.1101/2021.10.28.465122 — neuroscience — Posted on 2024-08-14

2941 Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related multisystem neurodegenerative deficits

Laguna, A.; Penuelas, N.; Gonzalez-Sepulveda, M.; Nicolau, A.; Arthaud, S.; Guilliard-Sirieix, C.; Lorente-Picon, M.; Compte, J.; Miquel-Rio, L.; Xicoy, H.; Liu, J.; Parent, A.; Cuadros, T.; Romero-Gimenez, J.; Pujol, G.; Gimenez-Llort, L.; Fort, P.; Bortolozzi, A.; Carballo-Carbajal, I.; Vila, M.

10.1101/2023.08.08.552400 — neuroscience — Posted on 2024-08-14

2942 Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage

Boerner, K.; Blood, P. D.; Silverstein, J. C.; Ruffalo, M.; Satija, R.; Teichmann, S. A.; Pryhuber, G.; Misra, R. S.; Purkerson, J. M.; Fan, J.; Hickey, J. W.; Molla, G.; Xu, C.; Zhang, Y.; Weber, G. M.; Jain, Y.; Qaurooni, D.; Kong, Y.; HRA Team, ; Bueckle, A.; Herr, B. W.

10.1101/2024.03.27.587041 — bioinformatics — Posted on 2024-08-14

2943 Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain

Zuniga, N.; Earls, N.; Denos, A.; Elison, J.; Jones, B.; Smith, E.; Moran, N.; Brown, K.; Romero, G.; Hyer, C.; Wagstaff, K.; Almughamsi, H.; Transtrum, M.; Price, J. C.

10.1101/2024.08.13.607719 — biochemistry — Posted on 2024-08-14

2944 Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence

Sanchez-Martinez, R.; Arani, A.; Krupovic, M.; Weitz, J. S.; Santos, F.; Anton, J.

10.1101/2024.07.30.605759 — microbiology — Posted on 2024-08-14

2945 In vitro evolution of ciprofloxacin resistance in Neisseria commensals and derived mutation population dynamics in natural Neisseria populations

Robinson, L. R.; McDevitt, C. J.; Regan, M. R.; Quail, S. L.; Wadsworth, C. B.

10.1101/2024.07.16.603762 — microbiology — Posted on 2024-08-14

2946 Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA

Pizzo, M. E.; Plowey, E. D.; Khoury, N.; Kwan, W.; Abettan, J.; DeVos, S. L.; Discenza, C. B.; Earr, T.; Joy, D.; Lye-Barthel, M.; Roche, E.; Chan, D.; Dugas, J. C.; Gadkar, K.; Meisner, R.; Sebalusky, J.; Silva Amaral, A. C.; Becerra, I.; Chau, R.; Chow, J.; Clemens, A. J.; Dennis, M. S.; Duque, J.; Fusaro, L.; Getz, J. A.; Kariolis, M. S.; Kim, D. J.; Leung, A. W.-S.; Nguyen, H. N.; Thomsen, E. R.; Sanchez, P. E.; Shan, L.; Silverman, A. P.; Solanoy, H.; Tong, R.; Calvert, M. E. K.; Watts, R. J.; Thorne, R. G.; Weinreb, P. H.; Walsh, D. M.; Lewcock, J. W.; Bussiere, T.; Zuchero, Y. J. Y.

10.1101/2024.07.26.604664 — neuroscience — Posted on 2024-08-14

2947 CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.

Ackloo, S.; Arrowsmith, C. H.; Ban, F.; Barden, C. J.; Beck, H.; Beranek, J.; Berenger, F.; Bolotokova, A.; Bret, G.; Breznik, M.; Carosati, E.; Chau, I.; Chen, Y.; Cherkasov, A.; Della Corte, D.; Denzinger, K.; Dong, A.; Draga, S.; Dunn, I.; Edfeldt, K.; Edwards, A.; Eguida, M.; Eisenhuth, P.; Friedrich, L.; Fuerll, A.; Gardiner, S.; Gentile, F.; Ghiabi, P.; Gibson, E.; Glavatskikh, M.; Gorgulla, C.; Guenther, J.; Gunnarsson, A.; Guseve, F.; Gutkin, E.; Hillisch, A.; Hoffer, L.; Hogner, A.; Irwin, J. J.; Isayev, O.; Ivanova, A.; Jacquemard, C.; Jarrett, A. J.; Jensen, J. H.; Kireev, D.; Klebe

10.1101/2024.07.18.603797 — biochemistry — Posted on 2024-08-14

2948 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays

Van Vranken, J. G.; Li, J.; Mintseris, J.; Wei, T.-Y.; Sniezek, C. M.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D. K.

10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-08-14

2949 Cell-type-specific alternative splicing in the cerebral cortex of a Schinzel-Giedion Syndrome patient variant mouse model

Jones, E. F.; Howton, T. C.; Soelter, T. M.; Crumley, A. B.; Lasseigne, B. N.

10.1101/2024.06.26.600823 — genomics — Posted on 2024-08-14

2950 Parthenogenesis, sexual conflict, and selection on fertilization rates in switching environments

Liu, X.; Pitchford, J. W.; Constable, G. W. A.

10.1101/2023.06.09.544312 — evolutionary biology — Posted on 2024-08-14

2951 CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Ji, L.; Wang, A.; Sonthalia, S.; Naiman, D. Q.; Younes, L.; Colantuoni, C.; Geman, D.

10.1101/2023.04.06.535943 — genomics — Posted on 2024-08-14

2952 Multicellular, fluid flow-inclusive hepatic in vitro models using NANOSTACKS™: a relevant-organ model for drug response prediction

Talari, A.; Sbordoni, R.; Hoti, V.; Patel, I. I.; Martin, F. L.; Raza, A.; Llabjani, V.

10.1101/2024.08.12.607396 — cell biology — Posted on 2024-08-14

2953 A non-catalytic function of a disintegrin and metalloprotease 10 determines hepatic progenitor cell fate

Woehner, B.; Mueller, M.; Pearen, M.; Koehn-Gaone, J.; Gorki, L.; Philippsen, R.; Gogoi-Tiwari, J.; John, C.; Scheja, L.; Krause, F.; Halwachs, B.; Barikbin, R.; Schwinge, D.; Rose-John, S.; Saftig, P.; Schramm, C.; Olynyk, J.; Heeren, J.; Tirnitz-Parker, J. E.; Ramm, G. A.; Schmidt-Arras, D.

10.1101/2024.08.14.607697 — cell biology — Posted on 2024-08-14

2954 Cryo-electron tomography of the actin cytoskeleton and membrane organization during lamellipodia formation using optogenetics

Inaba, H.; Imasaki, T.; Aoyama, K.; Yoshihara, S.; Takazaki, H.; Kato, T.; Goto, H.; Mitsuoka, K.; Nitta, R.; Nakata, T.

10.1101/2024.08.13.607852 — cell biology — Posted on 2024-08-14

2955 Subcellular Region Morphology Reflects Cellular Identity

ROMAN, A. C.; Diaz-Pizarro, A.; Del Valle-Del Pino, N.; Olivera-Gomez, M.; Cumplido-Laso, G.; Benitez, D. A.; Carvajal-Gonzalez, J. M.; Mulero-Navarro, S.

10.1101/2024.08.14.607889 — cell biology — Posted on 2024-08-14

2956 CD24 regulates extracellular vesicle release via an aSMase/PI3K/mTORC2/ROCK/actin pathway in B lymphocytes

Phan, H. D.; Squires, W. R. B.; Mayne, K. E.; Kelly, G. R.; Jafardoust, R.; Christian, S. L.

10.1101/2024.08.14.607772 — cell biology — Posted on 2024-08-14

2957 PDPN/CLEC-2 axis modulates megakaryocyte subtypes in a hematopoietic stem cell-regulating megakaryocyte-dominant manner

Nara, R.; Notoh, H.; Sasaki, T.; Tsukiji, N.; Kamata, A.; Suzuki, N.; Suzuki, A.; Okamoto, S.; Kanematsu, T.; Suzuki, N.; Katsumi, A.; Kojima, T.; Suzuki-Inoue, K.; Matsushita, T.; Tamura, S.

10.1101/2024.08.14.607891 — cell biology — Posted on 2024-08-14

2958 ARPE-19 Epithelial Cells Fail To Initiate Type-I Interferon Signaling in Response to Human Cytomegalovirus Infection.

Andrade-Medina, M.; Greco, T. M.; Cristea, I. M.; Oberstein, A.

10.1101/2024.08.01.606090 — microbiology — Posted on 2024-08-14

2959 A gene-regulatory network model for density-dependent and sex-biased dispersal evolution during range expansions.

Deshpande, J. N.; Fronhofer, E. A.

10.1101/2023.07.18.549508 — evolutionary biology — Posted on 2024-08-14

2960 Generation and characterisation of mouse models of Duchenne Muscular Dystrophy (DMD)

Arudkumar, J.; Chey, Y. C. J.; Piltz, S. G.; Thomas, P. Q.; Adikusuma, F.

10.1101/2024.08.11.607106 — molecular biology — Posted on 2024-08-14

2961 Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes

Keller, M. I.; Nishijima, S.; Podlesny, D.; Kim, C. Y.; Robbani, S. M.; Schudoma, C.; Fullam, A.; Richter, J.; Letunic, I.; Akanni, W.; Orakov, A.; Schmidt, T. S.; Marotta, F.; Trebicka, J.; Kuhn, M.; Van Rossum, T.; Bork, P.

10.1101/2024.08.13.607711 — microbiology — Posted on 2024-08-14

2962 Sensory-memory interactions via modular structure explain errors in visual working memory

Yang, J.; Zhang, H.; Lim, S.

10.1101/2023.11.09.566396 — neuroscience — Posted on 2024-08-14

2963 Decoding the Microbiome-Metabolome Nexus: A Systematic Benchmark of Integrative Strategies

Mangnier, L.; Bodein, A.; Mariaz, M.; Scott-Boyer, M.-P.; Mathieu, A.; Vashist, N.; Bramble, M.; Droit, A.

10.1101/2024.01.26.577441 — bioinformatics — Posted on 2024-08-14

2964 Prolonged Cell Cycle Arrest in Response to DNA damage in Yeast Requires the Maintenance of DNA Damage Signaling and the Spindle Assembly Checkpoint

Zhou, F. Y.; Waterman, D. P.; Ashton, M.; Caban-Penix, S.; Memisoglu, G.; Eapen, V. V.; Haber, J. E.

10.1101/2023.05.15.540538 — genetics — Posted on 2024-08-14

2965 H2A.Z deposition at meiotic prophase I underlies homologous recombination and pachytene genome activation during male meiosis

Sun, S.; Jiang, Y.; Jiang, N.; Zhang, Q.; Pan, H.; Huang, F.; Zhang, X.; Guo, Y.; You, X.; Gong, K.; Wei, W.; Liu, H.; Song, Z.; Song, Y.; Tang, X.; Yu, M.; Li, R.; Lin, X.

10.1101/2024.06.06.597721 — developmental biology — Posted on 2024-08-14

2966 Quantification of grapevine yield losses as a function downy mildew severity on foliage and cluster

Fabre, F.; Delbac, L.; Poeydebat, C.; Zaffaroni, M.

10.1101/2024.02.28.582447 — microbiology — Posted on 2024-08-14

2967 SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated nef variant

Yamamoto, H.; Matano, T.

10.1101/2023.04.19.537602 — immunology — Posted on 2024-08-14

2968 CRISPR-Cas9 mediated deletions of FvMYB46 reduces fruit set and biosynthesis of flavonoids in Fragaria vesca

Rai, A.; Skarn, M. N.; Tengs, T.; Elameen, A.; Amundsen, M. R.; Bjora, O. S.; Haugland, L. K.; Yakovlev, I. A.; Brurberg, M. B.; Thorstensen, T.

10.1101/2024.08.07.607017 — plant biology — Posted on 2024-08-14

2969 Efficient sampling designs to assess biodiversity spatial autocorrelation : should we go fractal?

Laroche, F.

10.1101/2022.07.29.501974 — ecology — Posted on 2024-08-14

2970 Change in functional trait diversity mediates the effects of nutrient addition on grassland stability

Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, S.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.

10.1101/2022.09.16.508233 — ecology — Posted on 2024-08-14

2971 SIV-specific neutralizing antibody induction following selection of a PI3K drive-attenuated nef variant

Yamamoto, H.; Matano, T.

10.1101/2023.04.19.537602 — immunology — Posted on 2024-08-14

2972 Recombinant dimeric PDZ protein inhibitors for long-term relief of chronic pain by AAV therapeutics

Noes-Holt, G.; Jensen, K. L.; Richner, M.; Baro, R. C.; Sivertsen, L.; Jager, S. E.; Fernandez, L. J.; Andersen, R. C.; Lilja, J. H.; Larsen, A. H.; Kowenicki, M. B.; Boesgaard, S. P.; Houser, G. A.; Christiansen, N. R.; Tappe-Theodor, A. E.; Vaegter, C. B.; Kuner, R.; Madsen, K. L.; Soerensen, A. T.

10.1101/2023.03.03.530962 — neuroscience — Posted on 2024-08-14

2973 PeakPerformance - a tool for Bayesian inference-based fitting of LC-MS/MS peaks

Niesser, J.; Osthege, M.; von Lieres, E.; Wiechert, W.; Noack, S.

10.1101/2024.02.17.580815 — systems biology — Posted on 2024-08-14

2974 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D

Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.

10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-08-14

2975 Low T cell diversity is associated with poor outcome in bladder cancer: a comprehensive longitudinal analysis of the T cell receptor repertoire

Kjaer, A.; Kristjansdottir, N.; Juul, R. I.; Nordentoft, I.; Birkenkamp-Demtroder, K.; Ahrenfeldt, J.; Strandgaard, T.; Radif, D.; Hodgson, D.; Abbosh, C.; Aerts, H. J.; Agerbaek, M.; Jensen, J. B.; Birkbak, N. J.; Dyrskjot, L.

10.1101/2024.05.30.596555 — cancer biology — Posted on 2024-08-14

2976 Event-based Single Molecule Localization Microscopy (eventSMLM) for High Spatio-Temporal Super-resolution Imaging

Basumatary, J.; S, A.; Pant, N.; Ramanathan, V.; Thakur, C. S.; Mondal, P. P.

10.1101/2023.12.30.573392 — biophysics — Posted on 2024-08-14

2977 Bayesian Estimation of Allele-Specific Expression in the Presence of Phasing Uncertainty

Zou, X.; Gomez, Z. W.; Reddy, T. E.; Allen, A. S.; Majoros, W. H.

10.1101/2024.08.09.607371 — bioinformatics — Posted on 2024-08-14

2978 Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone

Li, Y.-X.; Kang, X.-L.; Li, Y.-L.; Wang, X.-P.; Yan, Q.; Wang, J.-X.; Zhao, X.-F.

10.1101/2024.02.27.582377 — developmental biology — Posted on 2024-08-14

2979 MIRO1 controls energy production and proliferation of smooth muscle cells

Qian, L.; Koval, O. M.; Endoni, B. T.; Juhr, D.; Stein, C. C.; Allamargot, C.; Lin, L.-H.; Guo, D.-F.; Rahmouni, K.; Boudreau, R. L.; Streeter, J.; Thiel, W. H.; Grumbach, I. M.

10.1101/2024.08.13.607854 — cell biology — Posted on 2024-08-13

2980 A novel functional coordination in UNC-13 regulates neurotransmitter release

Liu, H.; Li, L.; Wang, J.; Hu, J.; Xia, J.; Ma, C.; Kang, L.; Hu, Z.

10.1101/2024.08.12.607578 — neuroscience — Posted on 2024-08-13

2981 A multi-model approach defines function altering MECP2 missense variants identified in individuals with autism spectrum disorder

Loewen, C.; Chen, E.; Schmitt, J.; McIntosh, G.; Singh, A.; Young, B.; Lian, T.; Liu, J.; Khan, V.; Chen, K.; Liston, J. B.; MacDonald, L.; Wang, B.; Medina Giro, S.; Boehme, B.; Das, M.; Indran, S.; Rogic, S.; Pavlidis, P.; Chao, J.; Allan, D. W.

10.1101/2024.08.13.607763 — neuroscience — Posted on 2024-08-13

2982 A cleaved cytosolic FOXG1 promotes excitatory neurogenesis by modulation of mitochondrial translation - a new therapeutic target for brain disorders.

Bruce, H.; Halpern, M. E.; Monfries, C.; Suleyman, O.; Hamid, F.; Houart, C.

10.1101/2024.08.13.607559 — neuroscience — Posted on 2024-08-13

2983 A bone-derived protein primes rapid visual escape via GPR37 receptor in a subpopulation of VTA GABAergic neurons

Liu, X.; Lai, J.; Gao, X.; Wang, L.; Hu, Y.; Liao, G.; Ma, S.; Feng, B.; Yang, L.; Qian, Z.; Tan, L.; Li, X.; Wang, L.

10.1101/2024.08.12.607510 — neuroscience — Posted on 2024-08-13

2984 Lower Aperiodic Activity is Associated with Reduced Verbal Fluency Performance Across Adulthood

McKeown, D. J.; Roberts, E.; Finley, A. J.; Kelley, N. J.; Keage, H. A. D.; Schinazi, V. R.; Baumann, O.; Moustafa, A. A.; Angus, D. J.

10.1101/2024.08.13.607827 — neuroscience — Posted on 2024-08-13

2985 Population coding of predator imminence in the hypothalamus

Cheung, K. Y. M.; Nair, A.; Li, L.-y.; Shapiro, M. G.; Anderson, D. J.

10.1101/2024.08.12.607651 — neuroscience — Posted on 2024-08-13

2986 Human-specific features of cerebellar astrocytes and Purkinje cells: an anatomical comparison with mice and macaques

Hercher, C.; Ellerbeck, K.; Toutee, L.; Ye, X.; Mpai, R.; Davoli, M. A.; Watt, A. J.; Murai, K. K.; Turecki, G.; Mechawar, N.

10.1101/2024.08.13.607849 — neuroscience — Posted on 2024-08-13

2987 Cognitive dysfunction following brain trauma results from sex-specific reactivation of the developmental pruning processes

Arizanovska, D.; Dallera, C. A.; Folorunso, O. O.; Bush, G. F.; Frye, J. B.; Doyle, K. P.; Jagid, J. R.; Monaco, B. A.; Cordeiro, J. G.; Atkins, C. M.; Griswold, A. J.; Liebl, D. J.

10.1101/2024.08.13.607610 — neuroscience — Posted on 2024-08-13

2988 Adolescent THC impacts on mPFC dopamine-mediated cognitive processes in male and female rats

Martinez, M. X.; Alizo Vera, V.; Ruiz, C. M.; Floresco, S. B.; Mahler, S. V.

10.1101/2024.04.12.588937 — animal behavior and cognition — Posted on 2024-08-13

2989 Axonal mitochondria regulate gentle touch response through control of axonal actin dynamics

Hegde, S.; Modi, S.; Deih, E. W.; Glomb, O. V.; Yogev, S.; Hoerndli, F.; Koushika, S. P.

10.1101/2024.08.13.607780 — cell biology — Posted on 2024-08-13

2990 Galvanotactic directionality of cell groups depends on group size

Copos, C.; sun, y.; Zhu, K.; Zhang, Y.; Reid, B.; Draper, B. W.; Lin, F.; Yue, H.; Bernadskaya, Y.; Zhao, M.; Mogilner, A.

10.1101/2024.08.13.607794 — cell biology — Posted on 2024-08-13

2991 One step 4x and 12x 3D-ExM: robust super-resolution microscopy in cell biology

Norman, R.; Chen, Y.-C.; Recchia, E.; Loi, J.; Rosemarie, Q.; Lesko, S.; Patel, S.; Sherer, N. M.; Takaku, M.; Burkard, M.; Suzuki, A.

10.1101/2024.08.13.607782 — cell biology — Posted on 2024-08-13

2992 Mannose receptor (MRC1) mediates uptake of dextran in macrophages via receptor-mediated endocytosis

Wollman, J.; Wanniarachchi, K.; Pradhan, B.; Huang, L.; Kerkvliet, J. G.; Hoppe, A. D.; Thiex, N. W.

10.1101/2024.08.13.607841 — cell biology — Posted on 2024-08-13

2993 Identification of the Polo-like kinase substrate required for homologous synapsis in C. elegans

Gold, A. L.; Hurlock, M. E.; Guevara, A. M.; Isenberg, L. Y. Z.; Kim, Y.

10.1101/2024.08.13.607834 — cell biology — Posted on 2024-08-13

2994 HI-FISH: WHOLE BRAIN IN SITU MAPPING OF NEURONAL ACTIVATION IN DROSOPHILA DURING SOCIAL BEHAVIORS AND OPTOGENETIC STIMULATION

Watanabe, K.; Chiu, H. V.; Anderson, D. J.

10.1101/2023.09.28.560045 — neuroscience — Posted on 2024-08-13

2995 Inference technique for the synaptic conductances in rhythmically active networks and application to respiratory central pattern generation circuits

Molkov, Y. I.; Borgmann, A.; Koizumi, H.; Hama, N.; Zhang, R.; Smith, J. C.

10.1101/2024.08.12.607656 — neuroscience — Posted on 2024-08-13

2996 Single-cell transcriptomics reveals cellular hierarchies and aberrant CTS contraction-mediated premature hair regression in androgenetic alopecia

Li, G.; Yang, L.; Duan, S.; Chen, M.; Zhang, Y.; Liu, F.; Tang, Y.; Wang, Y.; Li, J.; Xu, S.; Wu, Z.; Wang, B.; Zhao, Z.; Shi, W.; Xie, H.; Deng, Z.; Li, J.

10.1101/2023.12.25.573294 — pathology — Posted on 2024-08-13

2997 The Aryl Hydrocarbon Receptor Controls IFNγ-Induced Immune Checkpoints PD-L1 and IDO via the JAK/STAT Pathway in Lung Adenocarcinoma

Snyder, M.; Wang, Z.; Lara, B.; Fimbres, J.; Pichardo, T.; Mazzilli, S. A.; Kahn, M. M.; Duggineni, V.; Monti, S.; Sherr, D. H.

10.1101/2024.08.12.607602 — cancer biology — Posted on 2024-08-13

2998 TooT-PLM-P2S: Incorporating secondary structure information into protein language models

Ghazikhani, H.; Butler, G.

10.1101/2024.08.13.607781 — bioinformatics — Posted on 2024-08-13

2999 A simple method for methanol quantification in Spirits using UV Visible Spectroscopy and FTIR

Shadrack, R. S.; Kotra, K. K.; Tari, D.; Tabi, H.; Botleng, J.; Kelep, R.; Regenvanu, L.

10.1101/2024.08.12.607685 — biochemistry — Posted on 2024-08-13

3000 Personality homophily drives female friendships in a feral ungulate

Bhattacharjee, D.; Flay, K. J.; McElligott, A. G.

10.1101/2024.06.23.600227 — animal behavior and cognition — Posted on 2024-08-13

3001 Discovering Root Causal Genes with High Throughput Perturbations

Strobl, E. V.; Gamazon, E. R.

10.1101/2024.01.13.574491 — genomics — Posted on 2024-08-13

3002 Enhancing transcriptome expression quantification through accurate assignment of long RNA sequencing reads with TranSigner

Ji, H. J.; Pertea, M.

10.1101/2024.04.13.589356 — genomics — Posted on 2024-08-13

3003 Alteration of long and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

Nishi, K.; Sakamaki, T.; Nagasaka, A.; Kao, K. S.; Sadaoka, K.; Asano, M.; Yamamoto, N.; Takaori-Kondo, A.; Miyanishi, M.

10.1101/2024.01.18.576239 — developmental biology — Posted on 2024-08-13

3004 Growth regulation bringing modularity to morphogenesis of complex three-dimensional exoskeletons

Ito, H. C.; Uchiumi, Y.

10.1101/2024.05.06.592547 — developmental biology — Posted on 2024-08-13

3005 Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies

Ishii, Y.; Orr, J. C.; El Mdawar, M.-B.; Bairros de Pilger, D. R.; Pearce, D. R.; Lazarus, K. A.; Graham, R. E.; Nikolic, M. Z.; Ketteler, R.; Carragher, N. O.; Janes, S. M.; Hynds, R. E.

10.1101/2024.08.13.606573 — cell biology — Posted on 2024-08-13

3006 Single-Molecule Barcoding Technology for Single-Cell Genomics

Garcia-Bassets, I.; Mo, G.; Xia, Y.; Wu, T.-C.; Mekuria, I.; Mikhaylova, V.; Rzepka, M.; Kawamura, T.; Chang, P. L.; Paasch, A.; Pham, L.; Venugopal, S. S.; Sanchez, S.; de Souza, J. S.; Yao, L.; Gu, S.; Bodai, Z.; Komor, A. C.; Muotri, A. R.; Wang, J.; Wang, Y.; Lei, M.; Almenar-Queralt, A.; Chen, Z.

10.1101/2024.08.13.607508 — molecular biology — Posted on 2024-08-13

3007 Human DCP1 is crucial for mRNA decapping and possesses paralog-specific gene regulating functions

Chen, T.-W.; Liao, H.-W.; Noble, M.; Siao, J.-Y.; Cheng, Y.-H.; Chiang, W.-C.; Lo, Y.-T.; Chang, C.-T.

10.1101/2023.09.04.556219 — molecular biology — Posted on 2024-08-13

3008 Control of pili synthesis and putrescine homeostasis in Escherichia coli

Mehta, I.; Hogins, J.; Hall, S.; Vragel, G.; Ambagaspitiye, S.; Zimmern, P. E.; Reitzer, L.

10.1101/2024.08.13.607059 — microbiology — Posted on 2024-08-13

3009 SICKO: Systematic Imaging of Caenorhabditis Killing Organisms

Espejo, L. S.; Freitas, S.; Hofschneider, V.; Chang, L.; Antenor, A.; Balsa, J.; Haskins, A.; DeNicola, D.; Dang, H.; Hamming, S.; Kelser, D.; Sutphin, G. L.

10.1101/2023.02.17.529009 — immunology — Posted on 2024-08-13

3010 Brain Age Prediction: Deep Models Need a Hand to Generalize

Rajabli, R.; Soltaninejad, M.; Fonov, V.; Bzdok, D.; Collins, L.

10.1101/2024.06.11.598576 — neuroscience — Posted on 2024-08-13

3011 Implicit motor adaptation patterns in a redundant motor task manipulating a stick with both hands

Kobayashi, T.; Nozaki, D.

10.1101/2023.06.13.544873 — neuroscience — Posted on 2024-08-13

3012 Cross-species real time detection of trends in pupil size fluctuation

Kronemer, S. I.; Gobo, V. E.; Walsh, C. R.; Teves, J. B.; Burk, D. C.; Shahsavarani, S.; Gonzalez-Castillo, J.; Bandettini, P. A.

10.1101/2024.02.12.579393 — neuroscience — Posted on 2024-08-13

3013 Untargeted metabolomics reveals anion and organ-specific biochemistry of salinity tolerance in willow

Sas, E.; Fremont, A.; Gonzalez, E.; Sarrazin, M.; Barnabe, S.; Labrecque, M.; Brereton, n. J. B.; Pitre, F. E.

10.1101/2024.07.16.603755 — plant biology — Posted on 2024-08-13

3014 An extra-glycolytic function for hexokinase 2 as an RNA-binding protein regulating SOX10 mRNA translation in melanoma

Dian, A.-L.; Moya-Plana, A.; Claps, G.; Labbe, C. M.; Quidville, V.; Baille, D.; Roy, S.; Raynal, V.; Baulande, S.; Robert, C.; Vagner, S.

10.1101/2024.08.13.607712 — cancer biology — Posted on 2024-08-13

3015 The pro-tumoral and anti-tumoral roles of EphA4 on T regulatory cells and tumor associated macrophages during HNSCC tumor progression.

Corbo, S.; Nguyen, D.; Bhatia, S.; Darragh, L. B.; Abdelazeem, K. N. M.; Van Court, B.; Olimpo, N. A.; Gadwa, J.; Yu, J.; Hodgson, C.; Samedi, V.; Garcia, E. S.; Siu, L.; Saviola, A.; Heasley, L. E.; Knitz, M. W.; Pasquale, E. B.; Karam, S. D.

10.1101/2024.08.13.607778 — cancer biology — Posted on 2024-08-13

3016 Examining the Biophysical Properties of the Inner Membrane of Gram-Negative ESKAPE Pathogens

Gazerani, G.; Piercey, L. R.; Reema, S.; Wilson, K. A.

10.1101/2024.08.13.607768 — biophysics — Posted on 2024-08-13

3017 A Chemoenzymatic Strategy for Site-Specific Glyco-Tagging of Native Proteins for the Development of Biologicals

Gimeno, A.; Ehlers, A. M.; Delgado, S.; Langenbach, J.-W. H.; van den Bos, L. J.; Kruijtzer, J. A. W.; Guigas, B. G. A.; Boons, G.-J.

10.1101/2024.08.13.607754 — biochemistry — Posted on 2024-08-13

3018 Discovery and description of gammanonin: a widely distributed natural product from Gammaproteobacteria

Costa, J. H.; Adams, E. E.; Johnston, C. W.

10.1101/2024.08.13.607837 — biochemistry — Posted on 2024-08-13

3019 An Automated High-throughput Affinity Capture-Mass Spectrometry Platform with Data-Independent Acquisition

Jing, H.; Richardson, P. L.; Potts, G. K.; Senaweera, S.; Marin, V. L.; McClure, R. A.; Banlasan, A.; Tang, H.; Kath, J.; Ma, R.; Williams, J.

10.1101/2024.08.13.607785 — biochemistry — Posted on 2024-08-13

3020 One-Pot Time-Induced Proteome Integral Solubility Alteration (OPTI-PISA) assay for automated and sensitive drug target identification

Meng, Z.; Saei, A. A.; Lyu, H.; Gaetani, M.; Zubarev, R. A.

10.1101/2024.08.13.607299 — biochemistry — Posted on 2024-08-13

3021 Quantitative and Kinetic Proteomics Reveal ApoE Isoform-dependent Proteostasis Adaptations in Mouse Brain

Zuniga, N.; Earls, N.; Denos, A.; Elison, J.; Jones, B.; Smith, E.; Moran, N.; Brown, K.; Romero, G.; Hyer, C.; Wagstaff, K.; Almughamsi, H.; Transtrum, M.; Price, J. C.

10.1101/2024.08.13.607719 — biochemistry — Posted on 2024-08-13

3022 Increased autonomous bioluminescence emission from mammalian cells by enhanced cofactor synthesis

Brinker, T.; Gregor, C.

10.1101/2024.08.13.607744 — biochemistry — Posted on 2024-08-13

3023 Sequence-directed covalent protein-RNA linkages using engineered HUH-Tags

Smiley, A.; Babilonia-Diaz, N.; Krueger, A. J.; Aihara, H.; Tompkins, K. J.; Lemmex, A. C.; Gordon, W. R.

10.1101/2024.08.13.607811 — biochemistry — Posted on 2024-08-13

3024 A Light Sensitive Hyaluronic Acid-based Hydrogel for 3D Culturing, Differentiation, and Harvesting of Mesenchymal Stromal Cells

Palmieri, F.; Gueye, M.; Vicario del Rio, L.; Bunschuh, S.; Chopra, P.; Mihaila, S.; Vermonden, T.; Levato, R.; Boons, G.-J.

10.1101/2024.08.13.607705 — biochemistry — Posted on 2024-08-13

3025 PMS2 has both pro-mutagenic and anti-mutagenic effects on repeat instability in the Repeat Expansion Diseases

Walker, A.; Jimenez, D. A.; Usdin, K.; Zhao, X.

10.1101/2024.08.13.607839 — genetics — Posted on 2024-08-13

3026 The conserved ATPase PCH-2 controls the number and distribution of crossovers by antagonizing crossover formation in C. elegans

Patel, B.; Grobler, M.; Herrera, A.; Logari, E.; Ortiz, V.; Bhalla, N.

10.1101/2024.08.13.607819 — cell biology — Posted on 2024-08-13

3027 ORMDL3 restrains type-I interferon signaling and anti-tumor immunity by promoting RIG-I degradation

zeng, q.; yao, c.; zhang, s.; mao, y.; wang, j.; wang, z.; sheng, c.; Chen, S.

10.1101/2024.08.13.607743 — molecular biology — Posted on 2024-08-13

3028 A comparison of super-resolution microscopy techniques for imaging tightly packed microcolonies of an obligate intracellular bacterium

North, A.; Sharma, V.; Pyrgaki, C.; Lim, J.; Atwal, S.; Saharat, K.; Wright, G.; Salje, J.

10.1101/2024.08.12.607698 — microbiology — Posted on 2024-08-13

3029 Dual quorum-sensing control of purine biosynthesis drives pathogenic fitness of Enterococcus faecalis

Zlitni, S.; Bowden, S.; Sberro, H.; Torres, M. D. T.; Vaughan, J. M.; Pinto, A. F. M.; Pinto, Y.; Fernandez, D.; Rost, H.; Saghatelian, A.; de la Fuente-Nunez, C.; Bhatt, A. S.

10.1101/2024.08.13.607696 — microbiology — Posted on 2024-08-13

3030 Refined Enterotyping Reveals Dysbiosis in Global Fecal Metagenomes

10.1101/2024.08.13.607711 — microbiology — Posted on 2024-08-13

3031 Porcine Nasal Organoids as a model to study the interactions between the swine nasal microbiota and the host

Bonillo-Lopez, L.; Carmona-Vicente, N.; Tarres-Freixas, F.; Kochanowski, K.; Martinez, J.; Perez, M.; Sibila, M.; Correa-Fiz, F.; Aragon, V.

10.1101/2024.08.13.606910 — microbiology — Posted on 2024-08-13

3032 Chromosomal curing drives prophage evolution and bacterial epidemiology

Kwun, M. J.; Ion, A. V.; Apagyi, K. J.; Croucher, N. J.

10.1101/2024.08.13.607808 — microbiology — Posted on 2024-08-13

3033 FhaA plays a key role in mycobacterial polar elongation and 1 asymmetric growth

Rosello, J.; Rivera, B.; Fialho, M. A.; Augusto, I.; Gil, M.; Forrellad, M. A.; Bigi, F.; Tano, A. R.; Urdaniz, E.; Piuri, M.; Miranda, K.; Wehenkel, A. M.; Alzari, P. M.; Malacrida, L.; Duran, R.

10.1101/2024.08.13.607006 — microbiology — Posted on 2024-08-13

3034 Pemivibart is less active against recent SARS-CoV-2 JN.1 sublineages

Wang, Q.; Guo, Y.; Ho, J.; Ho, D. D.

10.1101/2024.08.12.607496 — immunology — Posted on 2024-08-13

3035 APEX: Automated Protein EXpression in Escherichia coli

Kasprzyk, M.; Herrera, M. A.; Stracquadanio, G.

10.1101/2024.08.13.607171 — synthetic biology — Posted on 2024-08-13

3036 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds

Vasan, R.; Ferrante, A. J.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.

10.1101/2024.07.25.605164 — cell biology — Posted on 2024-08-13

3037 Mfn2 induces NCLX-mediated calcium release from mitochondria.

Kolitsida, P.; Saha, A.; Caliri, A. W.; Assali, E.; Riera, A. M.; Itskanov, S.; Magana, C. S.; Stork, B.; Shirihai, O. S.; Sekler, I.; Koehler, C. M.; van der Bliek, A. M.

10.1101/2024.08.05.606704 — cell biology — Posted on 2024-08-13

3038 Motor training improves impaired cortico-cerebellar connectivity in cerebellar ataxia

Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.

10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-08-13

3039 Urinary multi-omics reveal non-invasive diagnostic biomarkers in clear cell renal cell carcinoma

Jonsson, G.; Hofmann, M.; Oliveira, T.; Lemberger, U.; Stejskal, K.; Krssakova, G.; Sakic, I.; Novatchkova, M.; Mereiter, S.; Grabmann, G.; Koecher, T.; Kikic, Z.; Rechberger, G. N.; Zuellig, T.; Englinger, B.; Schmidinger, M.; Penninger, J. M.

10.1101/2024.08.12.607453 — cancer biology — Posted on 2024-08-13

3040 Building, Benchmarking, and Exploring Perturbative Maps of Transcriptional and Morphological Data

Celik, S.; Huetter, J.-C.; Melo-Carlos, S.; Lazar, N.; Mohan, R.; Tillinghast, C.; Biancalani, T.; Fay, M.; Earnshaw, B.; Haque, I.

10.1101/2022.12.09.519400 — bioinformatics — Posted on 2024-08-13

3041 Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Kobren, S. N.; Moldovan, M. A.; Reimers, R.; Traviglia, D.; Li, X.; Barnum, D.; Veit, A.; Corona, R. I.; Carvalho, G. d. V.; Willett, J.; Berselli, M.; Ronchetti, W.; Nelson, S. F.; Martinez-Agosto, J. A.; Sherwood, R.; Krier, J.; Kohane, I. S.; Undiagnosed Diseases Network, ; Sunyaev, S. R.

10.1101/2024.02.13.580158 — genetics — Posted on 2024-08-13

3042 How air temperature and solar radiation impact life history traits in a wild insect

Gardner, A. S.; Maclean, I. M. D.; Rodriguez-Munoz, R.; Tregenza, T.

10.1101/2024.08.13.607703 — evolutionary biology — Posted on 2024-08-13

3043 Generation and characterisation of mouse models of Duchenne Muscular Dystrophy (DMD)

Arudkumar, J.; Chey, Y. C. J.; Thomas, P. Q.; Adikusuma, F.

10.1101/2024.08.11.607106 — molecular biology — Posted on 2024-08-13

3044 Evidence that host-mediated epigenetic modifications regulate gene expression in Wolbachia pipientis

Papaleo, S.; Panelli, S.; Bitar, I.; Sterzi, L.; Nodari, R.; Comandatore, F.

10.1101/2024.04.08.588587 — microbiology — Posted on 2024-08-13

3045 Associations between oral microbiota pathogens and elevated depressive and anxiety symptoms in men

Kerff, F.; Dawson, S. L.; Loughman, A.; Jacka, F. N.; Pasco, J. A.; Williams, L. J.

10.1101/2024.08.10.606819 — microbiology — Posted on 2024-08-13

3046 Sleep defined by arousal threshold reveals decreases in corticocortical functional correlations independently from the conventional sleep stages

Picchioni, D.; Yang, F. N.; de Zwart, J. A.; Wang, Y.; Mandelkow, H.; Ozbay, P. S.; Chen, G.; Taylor, P. A.; Lam, N.; Chappel-Farley, M. G.; Chang, C.; Liu, J.; van Gelderen, P.; Duyn, J. H.

10.1101/2024.08.09.607376 — neuroscience — Posted on 2024-08-13

3047 Upregulation of DEK Expression in Uterine Myomas and Cervical Cancer as a Potential Prognostic Factor

Janiak, A.; Liu, X.; Koviazina, R.; Tan, P.; Kappes, F.; Sheng, F.; Petraglia, F.; Donati, C.; Tsigkou, A.

10.1101/2024.08.12.607532 — cancer biology — Posted on 2024-08-13

3048 SPEX: A modular end-to-end platform for high-plex tissue spatial omics analysis

Li, X.; Pechuan Jorge, X.; Risom, T.; Foo, C.; Prilipko, A.; Zubkov, A.; Chan, C.; Chang, P.; Peale, F.; Ziai, J.; Rost, S.; Hibar, D.; McGinnis, L.; Tabatsky, E.; Ye, X.; Bravo, H. C.; Shi, Z.; Nowicka, M.; Scherdin, J.; Cowan, J.; Giltnane, J.; Orlova, D.; Jesudason, R.

10.1101/2022.08.22.504841 — bioinformatics — Posted on 2024-08-13

3049 Cryo-EM Heterogeneity Analysis using Regularized Covariance Estimation and Kernel Regression

Gilles, M. A. T.; Singer, A.

10.1101/2023.10.28.564422 — bioinformatics — Posted on 2024-08-13

3050 A conditional protein diffusion model generates artificial programmable endonuclease sequences with enhanced activity

Zhou, B.; Zheng, L.; Wu, B.; Yi, K.; Zhong, B.; Tan, Y.; Liu, Q.; Lio, P.; Hong, L.

10.1101/2023.08.10.552783 — bioengineering — Posted on 2024-08-13

3051 CellCover Defines Temporal Progression in Conserved Cell Types and Informs oRG Evolution using scRNA-seq Data in Mammalian Neocortical Development

Ji, L.; Wang, A.; Sonthalia, S.; Naiman, D. Q.; Younes, L.; Colantuoni, C.; Geman, D.

10.1101/2023.04.06.535943 — genomics — Posted on 2024-08-13

3052 Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation

Zeeshan, M.; Rashpa, R.; Ferguson, D. J.; Mckeown, G.; Nugmanova, R.; Subodhi, A. K.; Beyeler, R.; Pashley, S. L.; Markus, R.; Brady, D.; Roques, M.; Bottrill, A. R.; Fry, A. M.; Pain, A.; vaughan, s.; Holder, A. A.; Tromer, E. C.; Brochet, M.; Tewari, R.

10.1101/2024.02.05.578160 — cell biology — Posted on 2024-08-13

3053 Boreal moss-microbe interactions are revealed through metagenome assembly of novel bacterial species

Ishak, S.; Rondeau-Leclaire, J.; Faticov, M.; Roy, S.; Laforest-Lapointe, I.

10.1101/2023.04.06.535926 — microbiology — Posted on 2024-08-13

3054 Sensory neurons regulate stimulus-dependent humoral immunity

Aguilar, D.; Zhu, F.; Millet, A.; Millet, N.; Germano, P.; Pisegna, J.; Akbari, O.; Doherty, T. A.; Swidergall, M.; Jendzjowsky, N.

10.1101/2024.01.04.574231 — immunology — Posted on 2024-08-13

3055 Heterogeneous Synaptic Homeostasis: A Novel Mechanism Boosting Information Propagation in the Cortex

Razi, F.; Sancristobal, B.

10.1101/2023.12.04.569905 — neuroscience — Posted on 2024-08-13

3056 Unraveling the impact of congenital deafness on individual brain organization

Amaral, L.; Wang, X.; Bi, Y.; Striem-Amit, E.

10.1101/2024.02.02.578685 — neuroscience — Posted on 2024-08-13

3057 Predicting the Sequence-Dependent Backbone Dynamics of Intrinsically Disordered Proteins

Qin, S.; Zhou, H.-X.

10.1101/2023.02.02.526886 — biophysics — Posted on 2024-08-13

3058 Pharmacological GCase Activity Enhancement Inhibits Tau Accumulation

Ciccaldo, M.; Perez-Carmona, N.; Piovesana, E.; Cano-Crespo, S.; Ruano, A.; Delgado, A.; Fregno, I.; Calvo-Flores Guzman, B.; Bellotto, M.; Molinari, M.; Taylor, J.; Papin, S.; Garcia-Collazo, A. M.; Paganetti, P.

10.1101/2024.08.13.607706 — cell biology — Posted on 2024-08-13

3059 Real-time identification of carbapenemase-producing Klebsiella pneumoniae lineages and outbreak detection using FT-IR ATR

Goncalves, A. B.; Alves, V.; Neves, I.; Read, A.; Pinheiro, N.; Henius, A. E.; Hasman, H.; Peixe, L.; Novais, A.

10.1101/2024.08.12.607659 — microbiology — Posted on 2024-08-13

3060 Deciphering Cargo Contents in Extracellular Vesicles of Candida haemulonii var. vulnera

de Oliveira, B. T. M.; Bitencourt, T. A.; Santos, P.; Pagano, A. D.; Pessoni, A. M.; Rezende, C. P.; Piraine, R. E. A.; Masson, A. P.; Faca, V. M.; Campos, V. F.; Alves, L. R.; Lopes Colombo, A.; Almeida, F.

10.1101/2024.08.12.607614 — microbiology — Posted on 2024-08-13

3061 Spatio-temporal Reconstruction of Gene Expression Patterns in Developing Mice

Avino Esteban, L.; Sharpe, J.

10.1101/2024.08.13.607727 — developmental biology — Posted on 2024-08-13

3062 Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response

Cottignies-Calamarte, A.; Marteau, F.; He, F.; Belouzard, S.; Dubuisson, J.; Tudor, D.; Viollet, B.; Bomsel, M.

10.1101/2024.02.29.582713 — immunology — Posted on 2024-08-13

3063 Silicone Wire Embolization-induced Acute Retinal Artery Ischemia and Reperfusion Model in Mouse: Gene Expression Provides Insight into Pathological Processes

Wang, Y.; Li, Y.; Feng, J.; Wang, C.; Wan, Y.; Lv, B.; Li, Y.; Xie, H.; Chen, T.; Wang, F.; Li, Z.; Yang, A.; Xiao, X.

10.1101/2024.05.01.592074 — neuroscience — Posted on 2024-08-13

3064 A Mathematical Model of Glomerular Fibrosis in Diabetic Kidney Disease to Predict Therapeutic Efficacy

Thomas, H. Y.; Ford Versypt, A. N.

10.1101/2023.04.02.535270 — systems biology — Posted on 2024-08-13

3065 VieMedKG: Knowledge Graph and Benchmark for Traditional Vietnamese Medicine

Trinh, T.; Dao, A.; Nhung, H. T. H.; Hy, T. S.

10.1101/2024.08.07.606195 — bioinformatics — Posted on 2024-08-13

3066 Investigative power of Genomic Informational Field Theory (GIFT) relative to GWAS for genotype-phenotype mapping

Kyratzi, P.; Matika, O.; Brassington, A. H.; Connie, C. E.; Xu, J.; Barrett, D. A.; Emes, R. D.; Archibald, A. L.; Paldi, A.; Sinclair, K. D.; Wattis, J.; Rauch, C.

10.1101/2024.04.16.589524 — genetics — Posted on 2024-08-13

3067 Optogenetic tools for inducing organelle membrane rupture

Nagashima, Y.; Eguchi, T.; Koyama-Honda, I.; Mizushima, N.

10.1101/2024.08.13.607738 — cell biology — Posted on 2024-08-13

3068 Dynamics of duplicated gene regulatory networks governing cotton fiber development following polyploidy

Xiong, X.; Zhu, D.; Grover, C. E.; Wendel, J. F.; Ma, X.; Hu, G.

10.1101/2024.08.12.607624 — bioinformatics — Posted on 2024-08-13

3069 Stochastic Character Mapping of Continuous Traits on Phlyogenies

Martin, B. S.; Weber, M. G.

10.1101/2024.08.12.607655 — evolutionary biology — Posted on 2024-08-13

3070 How air temperature and solar radiation impact life history traits in a wild insect

Gardner, A. S.; Maclean, I. M. D.; Rodriguez-Munoz, R.; Tregenza, T.

10.1101/2024.08.13.607703 — evolutionary biology — Posted on 2024-08-13

3071 Selecting sites for strategic surveillance of zoonotic pathogens: a case study in Panama

Cobos, M. E.; Dunnum, J. L.; Armien, B.; Gonzalez, P.; Juarez, E.; Salazar, J. R.; Cook, J. A.; Colella, J. P.

10.1101/2024.08.12.607103 — ecology — Posted on 2024-08-13

3072 Ciliary length regulation by intraflagellar transport in zebrafish

Sun, Y.; Chen, Z.; Jin, M.; Xie, H.; Zhao, C.

10.1101/2024.01.16.575975 — cell biology — Posted on 2024-08-13

3073 Arp2/3 iso-complexes limit t-tubule overgrowth to ensure myofiber formation and synchronous contraction

Pereira, A. R.; Soares, A. d. R.; Liu, T.; Ferreira, J. L.; Leal, G.; Faleiro, I.; Kogata, N.; Way, M.; Moores, C.; Gomes, E. R.

10.1101/2024.08.13.607563 — cell biology — Posted on 2024-08-13

3074 Vesiculation pathways in clathrin-mediated endocytosis

Wang, X.; Berro, J.; Ma, R.

10.1101/2024.08.13.607731 — cell biology — Posted on 2024-08-13

3075 Identification of bacteria involved in non-sulfate based hydrogen sulfide production in an aquaculture environment

Nguyen-tiet, A. M.; Puente-Sanchez, F.; Bertilsson, S.; Aalto, S. L.

10.1101/2024.04.12.589155 — microbiology — Posted on 2024-08-13

3076 Acute aerobic exercise does not modulate pain potentially due to differences in fitness levels and sex effects - results from a pharmacological fMRI study

Nold, J. I.; Fadai, T.; Buechel, C.

10.1101/2024.06.25.600579 — neuroscience — Posted on 2024-08-13

3077 Role of Mutual Information Profile Shifts in Assessing the Pathogenicity of Mutations on Protein Functions: The Case of Pyrin Variants Associated with Familial Mediterranean Fever

Hacisuleyman, A.; Gul, A.; Erman, B.

10.1101/2024.04.07.588500 — bioinformatics — Posted on 2024-08-13

3078 Isolation and characterisation of serine proteases and metalloproteases from the venom of African puff adders

Wilkinson, M. C.; Modahl, C.; Saviola, A.; Albulesco, L.-O.; Tianyi, F.-L.; Casewell, N. R.

10.1101/2024.05.31.596867 — biochemistry — Posted on 2024-08-13

3079 Non-Human Recognition of Orthography: How is it implemented and how does it differ from Human orthographic processing

Gagl, B.; Weyers, I.; Eisenhauer, S.; Fiebach, C. J.; Colombo, M.; Scarf, D.; Ziegler, J. C.; Grainger, J.; Guentuerkuen, O.; Mueller, J. L.

10.1101/2024.06.25.600635 — animal behavior and cognition — Posted on 2024-08-13

3080 Experimental validation of ecological coexistence theory to forecast extinction under rising temperatures.

Terry, C.

10.1101/2024.02.22.581553 — ecology — Posted on 2024-08-13

3081 Leveraging remote sensing to distinguish closely related beech species in assisted gene flow scenarios

Kaplan, G.; Mora, A.; Csillery, K.; Schuman, M. C.

10.1101/2024.08.12.607576 — ecology — Posted on 2024-08-13

3082 PINDER: The protein interaction dataset and evaluation resource

Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Rossi, E.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.

10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-08-13

3083 MCHelper automatically curates transposable element libraries across eukaryotic species

Orozco, S.; Sierra, P.; Durbin, R.; Gonzalez, J.

10.1101/2023.10.17.562682 — genomics — Posted on 2024-08-13

3084 Stable isotope analysis (δ13C, δ15N, δ34S) reveal divers manuring practices of rye (Secale cereale) in northern Europe since 1500 years

Schlütz, F.; Bittmann, F.; Jahns, S.; König, S.; Shumilovskikh, L.; Baumecker, M.; Kirleis, W.

10.1101/2024.08.12.607590 — ecology — Posted on 2024-08-13

3085 Chromatin remodeler CHD4 establishes chromatin states required for ovarian reserve formation, maintenance, and germ cell survival

Munakata, Y.; Hu, M.; Kitamura, Y.; Bynder, A. L.; Fritz, A. S.; Schultz, R. M.; Namekawa, S. H.

10.1101/2024.08.12.607691 — developmental biology — Posted on 2024-08-13

3086 Serotonin neuromodulation directs optic nerve regeneration

Saied-Santiago, K.; Baxter, M.; Mathiaparanam, J.; Granato, M.

10.1101/2024.08.12.607648 — developmental biology — Posted on 2024-08-13

3087 Spontaneous calcium transients in hair cell stereocilia

Hussain, S.; Sedlacek, M.; Cui, R.; Zhang-Hooks, W.; Bergles, D. E.; Shin, J.-B.; Kindt, K.; Kachar, B.

10.1101/2024.08.12.607658 — cell biology — Posted on 2024-08-13

3088 Human MeCP2 binds to promoters and inhibits transcription in an unmethylated S. cerevisiae genome

Howe, L. J.; Brown, J. A. R.; Ausio, J.; Ling, M. Y. M.

10.1101/2024.08.12.607623 — molecular biology — Posted on 2024-08-13

3089 The regulation of polar flagella assembly in Pseudomonas putida

Pulido-Sanchez, M.; Leal-Morales, A.; Lopez-Sanchez, A.; Cava, F.; Govantes, F.

10.1101/2023.12.15.571843 — microbiology — Posted on 2024-08-13

3090 Tertiary lymphoid structures are associated with enhanced macrophage activation, immune checkpoint expression and predict outcome in cervical cancer.

Gorvel, L.; Panouillot, M.; Rouviere, M.-S.; Billon, E.; Fattori, S.; Sonongbua, J.; Boucherit, N.; Ben Amara, A.; Quilichini, O.; GRANJEAUD, S.; Degos, C.; Carcopino, X.; Lambaudie, E.; Chretien, A.-S.; Sabatier, R.; Dieu-Nosjean, M.-C.; Olive, D.

10.1101/2023.08.17.552583 — immunology — Posted on 2024-08-13

3091 A transposase-derived gene required for human brain development

Jubierre Zapater, L.; Lewis, S.; Lopez Gutierrez, R.; Yamada, M.; Rodriguez Fos, E.; Planas-Felix, M.; Cameron, D.; Demarest, P.; Nabila, A.; Mueller, H.; Zhao, J.; Bergin, P.; Reed, C.; Chwat-Edelstein, T.; Pagnozzi, A.; Nava, C.; Bourel-Ponchel, E.; Dursun, A.; Ozgul, R. K.; Tuna Akar, H.; Maroofian, R.; Houlden, H.; Arshad Cheema, H.; Nadeem Anjum, M.; Zifarelli, G.; Essid, M.; Ben Hafsa, M.; Benrhouma, H.; Proekt, A.; Zhao, X.; Socci, N.; Hayes, M.; Bigot, Y.; Rabadan, R.; Torrents, D.; Kleinman, C. L.; Kruer, M. C.; Toth, M.; Kentsis, A.

10.1101/2023.04.28.538770 — neuroscience — Posted on 2024-08-13

3092 Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling

Le Gac, B.; Tournissac, M.; Belzic, E.; Picaud, S.; Dusart, I.; Soula, H.; Li, D.; Charpak, S.; Cauli, B.

10.1101/2024.03.27.586974 — neuroscience — Posted on 2024-08-13

3093 Influence of feedback transparency on motor imagery neurofeedback performance: the contribution of agency

Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.

10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-08-13

3094 Sub-cone visual resolution by active, adaptive sampling in the human foveola

Witten, J. L.; Lukyanova, V.; Harmening, W. M.

10.1101/2024.03.21.586052 — neuroscience — Posted on 2024-08-13

3095 Modelling inflammation-induced peripheral sensitization in a dish - more complex than expected?

Li, Y.; Lock, A.; Fedele, L.; Zebochin, I.; Sabate, A.; Siddle, M.; Cainarca, S.; Röderer, P.; Montag, K.; Tarroni, P.; Brüstle, O.; Shaw, T.; Taams, L.; Denk, F.

10.1101/2024.08.12.607558 — neuroscience — Posted on 2024-08-13

3096 Genome-wide Association Study of Rice Vegetative Biomass under Different Inorganic Nitrogen Forms: Ammonium or Nitrate

Kasemsap, P.; Cohen, I.; Bloom, A. J.

10.1101/2024.08.12.607622 — plant biology — Posted on 2024-08-13

3097 Natural variation suggests new mechanisms for bract development in Arabidopsis, desynchronising bract suppression from the floral transition

Dieudonne, S.; Kristianingsih, R.; Laine, S.; JESSON, B.; VIDAL, V.; Wells, R.; Morris, R.; Besnard, F.

10.1101/2024.08.12.607587 — plant biology — Posted on 2024-08-13

3098 Modeling Immunoglobulin light chain amyloidosis in Caenorhabditis elegans

Romeo, M.; Barzago, M. M.; Corbelli, A.; Maglioni, S.; Ventura, N.; Natale, C.; Conz, A.; Salmona, M.; Palladini, G.; Nuvolone, M.; Fiordaliso, F.; Merlini, G.; Diomede, L.

10.1101/2024.07.05.602215 — pathology — Posted on 2024-08-13

3099 Complete suspension culture of human induced pluripotent stem cells supplemented with suppressors of spontaneous differentiation

Matsuo-Takasaki, M.; Kambayashi, S.; Hemmi, Y.; Wakabayashi, T.; Shimizu, T.; An, Y.; Ito, H.; Takauchi, K.; Ibuki, M.; Kawashima, T.; Masayasu, R.; Suzuki, M.; Nishishita, N.; Kawai, Y.; Umekage, M.; Kato, T. M.; Noguchi, M.; Nakade, K.; Nakamura, Y.; Nakaishi, T.; Tsukahara, M.; Hayashi, Y.

10.1101/2023.10.08.561419 — bioengineering — Posted on 2024-08-13

3100 Enrichment of Cysteine S-palmitoylation using Sodium Deoxycholate Acid Precipitation - SDC-ACE

Larsen, M. R.; Jensen, P. T.; Palmisano, G.; Rhodes, C. J.

10.1101/2023.07.09.548252 — biochemistry — Posted on 2024-08-13

3101 DNA polymerase Lambda is anchored within the NHEJ synaptic complex via Ku70/80

Frit, P.; Amin, H.; Zahid, S.; Barboule, N.; Hall, C.; Matharu, G.; Hardwick, S. W.; Chauvat, J.; Britton, S.; Chirgadze, D. Y.; Ropars, V.; Charbonnier, J.-B.; Calsou, P.; Chaplin, A. K.

10.1101/2024.08.12.607588 — biochemistry — Posted on 2024-08-13

3102 Phylogenomic Insights into the Evolution and Origin of Nematoda

Qing, X.; Zhang, Y. M.; Sun, S.; Ahmed, M.; Lo, W.-S.; Bert, W.; Holovachov, O.; Li, H.

10.1101/2023.12.13.571554 — genomics — Posted on 2024-08-13

3103 Post-eclosion growth in the Drosophila Ejaculatory Duct is driven by Juvenile Hormone signaling and is essential for male fertility

Ramesh, N. A.; Box, A. M.; Buttitta, L.

10.1101/2024.08.12.607650 — developmental biology — Posted on 2024-08-13

3104 Transcriptional analysis of efferocytosis in mouse skin wounds

Krause, W. S. W.; King, D.; Horsley, V.

10.1101/2024.08.12.607219 — cell biology — Posted on 2024-08-13

3105 Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance

Kim, J.; Kim, D.; Kim, D.-K.; Lee, S.-H.; Jang, W.; Lim, D.-S.

10.1101/2024.01.31.578296 — cell biology — Posted on 2024-08-13

3106 A conserved regulation of cell expansion underlies notochord mechanics, spine morphogenesis, and endochondral bone lengthening

Voigt, B.; Frazier, K. E.; Yazdi, D.; Gontarz, P.; Zhang, B.; Sepich, D. S.; Solnica-Krezel, L.; GRAY, R. S.

10.1101/2024.08.12.607640 — developmental biology — Posted on 2024-08-13

3107 Integrative analysis of nanopore direct RNA sequencing data reveals a role of PUS7-dependent pseudouridylation in regulation of m6A and m5C modifications

Bansal, M.; Kundu, A.; Gupta, A.; Ding, J.; Gibson, A.; RudraRaju, S. V.; Sudarshan, S.; Ding, H.-F.

10.1101/2024.01.31.578250 — cancer biology — Posted on 2024-08-12

3108 Phosphate-dependent nuclear export via a novel NES class recognized by exportin Msn5

Fung, H. Y. J.; Mittal, S. R.; Niesman, A. B.; Jiou, J.; Shakya, B.; Yoshizawa, T.; Cansizoglu, A. E.; Rout, M. P.; Chook, Y. M.

10.1101/2024.08.12.607649 — biophysics — Posted on 2024-08-12

3109 Cross-species imputation and comparison of single-cell transcriptomic profiles

Zhang, R.; Yang, M.; Schreiber, J.; ODay, D. R.; Turner, J.; Shendure, J.; Disteche, C. M.; Deng, X.; Noble, W. S.

10.1101/2023.10.19.563173 — bioinformatics — Posted on 2024-08-12

3110 A Paper-based Loop-Mediated Isothermal Amplification (LAMP) Assay for Highly Pathogenic Avian Influenza

Kamel, M.; Davidson, J. L.; Verma, M. S.

10.1101/2024.08.12.607641 — bioengineering — Posted on 2024-08-12

3111 Altering translation allows E. coli to overcome chemically stabilized G-quadruplexes

Cueny, R. R.; Voter, A. F.; McKenzie, A. M.; Morgenstern, M.; Myers, K. S.; Place, M. M.; Peters, J. M.; Coon, J. J.; Keck, J. L.

10.1101/2024.08.12.607615 — biochemistry — Posted on 2024-08-12

3112 A Novel Blood-Based Epigenetic Clock for Intrinsic Capacity Predicts Mortality and is Associated with Clinical, Immunological and Lifestyle Factors

Fuentealba, M.; Rouch, L.; Guyonnet, S.; Lemaitre, J.-M.; de Souto Barreto, P.; Vellas, B.; Andrieu, S.; Furman, D.

10.1101/2024.08.09.607252 — genomics — Posted on 2024-08-12

3113 Promoters constrain evolution of expression levels of essential genes inEscherichia coli

Tsuru, S.; Hatanaka, N.; Furusawa, C.

10.1101/2024.05.20.594948 — evolutionary biology — Posted on 2024-08-12

3114 DNA methylation associates with sex-specific effects of experimentally increased yolk testosterone in wild nestlings

Sepers, B.; Ruuskanen, S.; van Mastrigt, T.; Mateman, C.; van Oers, K.

10.1101/2024.08.12.607609 — molecular biology — Posted on 2024-08-12

3115 Bovine highly pathogenic avian influenza virus stability and inactivation in the milk byproduct lactose

Kwon, T.; Gebhardt, J.; Lyoo, E.; Nooruzzaman, M.; Gaudreault, N. N.; Morozov, I.; Diel, D.; Richt, J. A.

10.1101/2024.08.12.607665 — microbiology — Posted on 2024-08-12

3116 Differential Drug Susceptibility Across Trichomonasvirus Species Allows for Generation of Varied Isogenic Clones of Trichomonas vaginalis

Hetzel, C. A.; Sampong, A. A.; Hurst-Manny, A. R.; Nibert, M. L.

10.1101/2024.08.12.607652 — microbiology — Posted on 2024-08-12

3117 Development of a highly efficient base editing system for Lactobacilli to improve probiotics and dissect essential functions

Mitsunobu, H.; Kita, Y.; Nambu-Nishida, Y.; Miyazaki, S.; Nakajima, K.; Taoka, K.-i.; Kondo, A.; Nishida, K.

10.1101/2024.08.12.607654 — microbiology — Posted on 2024-08-12

3118 Characteristics of human donor lungs utilized for research

Sarkar, N. R.; Garnica, L. A.; Stahlschmidt, E.; Byers, D. E.; Kulkarni, H. S.

10.1101/2024.08.10.607431 — immunology — Posted on 2024-08-12

3119 A novel candidate neuromarker of central motor dysfunction in childhood apraxia of speech

Anastasopoulou, I.; Cheyne, D. O.; Lieshout, P. V.; Wilson, P. H.; Ballard, K.; Johnson, B. W.

10.1101/2024.08.11.607491 — neuroscience — Posted on 2024-08-12

3120 Genetic analysis of retinal cell types reveals synaptic pathology in schizophrenia

Boudriot, E.; Stephan, M.; Rabe, F.; Smigielski, L.; Schmitt, A.; Falkai, P.; Ziller, M. J.; Rossner, M. J.; Homan, P.; Papiol, S.; Raabe, F. J.

10.1101/2024.08.09.607343 — neuroscience — Posted on 2024-08-12

3121 KMT2A oncoproteins induce epigenetic resistance to targeted therapies

Janssens, D. H.; Duran, M.; Otto, D. J.; Wu, W.; Xu, Y.; Kirkey, D.; Mullighan, C. G.; Yi, J. S.; Meshinchi, S.; Sarthy, J. F.; Ahmad, K.; Henikoff, S.

10.1101/2023.12.29.573681 — cancer biology — Posted on 2024-08-12

3122 Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer

wang, Y.

10.1101/2024.08.07.606975 — bioinformatics — Posted on 2024-08-12

3123 Simplified and Rapid Workflow Enhances Throughput of De Novo Sequencing of COVID-19 Neutralizing Antibodies

Xiong, Y.; Xiao, J.; Jiang, W.; Wang, J.; Bu, Q.; Chen, X.; Wu, Y.; Yu, R.; Yuan, Q.; Xia, N.

10.1101/2024.08.09.607349 — bioengineering — Posted on 2024-08-12

3124 Addressing the problem of lysine glycation prediction in proteins via Recurrent Neural Networks

Que-Salinas, U.; Martinez-Peon, D.; Mendez, G. M.; Arguelles-Lucho, P.; Reyes-Figueroa, A. D.; Scheckhuber, C. Q.

10.1101/2024.08.12.607666 — biochemistry — Posted on 2024-08-12

3125 Aerolysin nanopore structure revealed at high resolution in lipid environment

Anton, J.; Iacovache, I.; Bada Juarez, J. F.; Abriata, L.; Perrin, L.; Cao, C.; Marcaida, M. J.; Zuber, B.; Dal Peraro, M.

10.1101/2024.08.12.607338 — biochemistry — Posted on 2024-08-12

3126 High-coverage genome sequencing of Yayoi and Jomon individuals shed light on prehistoric human population history in East Eurasian

Ishiya, K.; Mizuno, F.; Gojobori, J.; Kumagai, M.; Taniguchi, Y.; Kondo, O.; Matsushita, M.; Matsushita, T.; Wang, L.; Kurosaki, K.; Ueda, S.

10.1101/2024.08.09.606917 — genomics — Posted on 2024-08-12

3127 Regulatory Roles of Long Non-Coding RNAs in Arterial Stiffness and Hypertension: Insights from Two African American Studies

Vargas, J.; Abbas, M.; Goodney, G.; Gaye, A.

10.1101/2024.08.11.607492 — genomics — Posted on 2024-08-12

3128 Identification of CNTN2 as a genetic modifier of PIGA-CDG through pedigree analysis of a family with incomplete penetrance and functional testing in Drosophila

Thorpe, H. J.; Pedersen, B. S.; Dietze, M.; Link, N. L.; Quinlan, A. R.; Bonkowsky, J. L.; Thomas, A.; Chow, C. Y.

10.1101/2024.08.12.607501 — genetics — Posted on 2024-08-12

3129 AbrB antirepressor AbbA is a competitive inhibitor of AbrB-phyC interaction

Neubauer, S.; Roessle, M.; Borriss, R.; Makarewicz, O.

10.1101/2024.08.12.607668 — molecular biology — Posted on 2024-08-12

3130 ARPE-19 Epithelial Cells Fail To Initiate Type-I Interferon Signaling in Response to Human Cytomegalovirus Infection.

Andrade-Medina, M.; Greco, T. M.; Ileana M Cristea, I. M.; Oberstein, A.

10.1101/2024.08.01.606090 — microbiology — Posted on 2024-08-12

3131 The Epithelial-to-Mesenchymal Transition Supports HCMV Infection and Biosynthesis in Mammary Epithelial Cells Through Two Distinct Mechanisms.

Golconda, P.; Andrade-Medina, M.; Matrenec, R.; McLachlan, A.; Oberstein, A.

10.1101/2024.08.12.607657 — microbiology — Posted on 2024-08-12

3132 Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins

Flick, H.; Venbakkam, A.; Singh, P. K.; Layish, B.; Huang, S.-W. K.; Radhakrishnan, R.; Kvaratskhelia, M.; Engelman, A. N.; Kane, M.

10.1101/2024.08.12.607676 — microbiology — Posted on 2024-08-12

3133 Commensal-derived short-chain fatty acids disrupt lipid membrane homeostasis in Staphylococcus aureus

Fletcher, J. R.; Hansen, L. A.; Martinez, R.; Freeman, C. D.; Thorns, N.; Villareal, A. R.; Penningroth, M. R.; Vogt, G. A.; Tyler, M.; Hines, K. M.; Hunter, R. C.

10.1101/2024.08.12.607382 — microbiology — Posted on 2024-08-12

3134 The microbiome of Total Suspended Particles (TSP) and its influence on the respiratory microbiome of healthy office workers

Solazzo, G.; Rovelli, S.; Iodice, S.; Chung, M.; Frimpong, M.; Bollati, V.; Ferrari, L.; Ghedin, E.

10.1101/2024.08.12.607611 — microbiology — Posted on 2024-08-12

3135 Diversity in Chemical Subunits and Linkages: A Key Molecular Determinant of Microbial Richness, Community Structure, Interactions, and Substrate Utilization

McCullough, H. C.; Song, H.-S.; Auchtung, J. M.

10.1101/2024.08.12.607625 — microbiology — Posted on 2024-08-12

3136 Pathogenic Th17 cells in arthritogenic mice share T cell receptor features with Wild-type Tregs

Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.

10.1101/2024.03.01.582868 — immunology — Posted on 2024-08-12

3137 Distinct T cell chromatin landscapes in scleroderma subtypes

Dou, D. R.; Zhao, Y.; Abe, B.; Li, R.; Zaba, L. C.; Aren, K.; Carns, M.; Chung, L. S.; Hinchcliff, M.; Chang, H. Y.

10.1101/2021.01.10.426131 — immunology — Posted on 2024-08-12

3138 Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection

Kim, J.; Yuan, Y.; Agaronyan, K.; Zhao, A.; Wang, V. D.; Gupta, G.; Essayas, H.; Kaminski, A.; McGovern, J.; Yu, S.; Woo, S.; Lee, C. J.; Gandhi, S.; Saber, T.; Saleh, T.; Hu, B.; Sun, Y.; Ishikawa, G.; Bain, W.; Evankovich, J.; Chen, L.; Yun, H.; Herzog, E.; Dela Cruz, C. S.; Ryu, C.; Sharma, L.

10.1101/2024.03.04.583378 — immunology — Posted on 2024-08-12

3139 Replay shapes abstract cognitive maps for efficient social navigation

Son, J.-Y.; Vives, M.-L.; Bhandari, A.; FeldmanHall, O.

10.1101/2023.12.19.572418 — neuroscience — Posted on 2024-08-12

3140 Valence and Salience Encoding in the Central Amygdala

Kong, M.-S.; Ancell, E.; Witten, D. M.; Zweifel, L. S.

10.1101/2024.07.05.602310 — neuroscience — Posted on 2024-08-12

3141 A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat

Cornwell, B. R.; Didier, P. R.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Hur, J.; Scott, Z. S.; Fox, A. S.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.

10.1101/2024.07.10.602972 — neuroscience — Posted on 2024-08-12

3142 Early life psychosocial stress increases binge-like ethanol consumption and CSF1R inhibition prevents stress-induced alterations in microglia and brain macrophage population density

Gironda, S. C.; Centanni, S. W.; Weiner, J. L.

10.1101/2024.07.27.605403 — neuroscience — Posted on 2024-08-12

3143 Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in Escherichia coli

Sotomayor, B.; Donahue, T. C.; Mahajan, S. P.; Taw, M. N.; Hulbert, S. W.; Bidstrup, E. J.; Owitipana, D. N.; Pang, A.; Yang, X.; Ghosal, S.; Alabi, C. A.; Azadi, P.; Gray, J. J.; Jewett, M. C.; Wang, L.-X.; DeLisa, M. P.

10.1101/2024.08.12.607630 — synthetic biology — Posted on 2024-08-12

3144 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action

Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.

10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-12

3145 Direct visualization of emergent metastatic features within an ex vivo model of the tumor microenvironment

Anandi, L.; Garcia, J.; Ros, M.; Janska, L.; Liu, J.; Carmona-Fontaine, C.

10.1101/2023.01.09.523294 — cancer biology — Posted on 2024-08-12

3146 Optimal control of combination immunotherapy for a virtual murine cohort in a glioblastoma-immune dynamics model

Anderson, H. G.; Takacs, G. P.; Harrison, J. K.; Rong, L.; Stepien, T. L.

10.1101/2024.04.29.591725 — cancer biology — Posted on 2024-08-12

3147 Towards optical measurements of membrane potential values in Bacillus subtilis using fluorescence lifetime

Roy, D.; Michalet, X.; Miller, E.; Weiss, S.

10.1101/2024.06.13.598880 — biophysics — Posted on 2024-08-12

3148 Machine Learning to Predict Gut Microbiomes of Agricultural Pests

Jobayer, M.; Taylor, A.; Hasan, M. R.; Ahmed, K. A.; Hossain, M. Z.

10.1101/2024.08.12.607564 — bioinformatics — Posted on 2024-08-12

3149 ESPClust: Unsupervised identification of modifiers for the effect size profile in omics association studies

Perez-Reche, F. J.; Cheetham, N.; Bowyer, R.; Thompson, E. J.; Tettamanzi, F.; Menni, C.; Steves, C.

10.1101/2024.08.11.607486 — bioinformatics — Posted on 2024-08-12

3150 Temporal variability enhances the acquisition of stereotyped communication signals

James, L. S.; Ruge, O.; Sakata, J. T.

10.1101/2024.04.18.590102 — animal behavior and cognition — Posted on 2024-08-12

3151 Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging

Tsai, Y.-T.; Seymen, N.; Thompson, I. R.; Zou, X.; Mumtaz, W.; Gerlevik, S.; Mufti, G. J.; Karimi, M. M.

10.1101/2024.02.09.579582 — genomics — Posted on 2024-08-12

3152 Bacterial ecology and evolution converge on seasonal and decadal scales

Rohwer, R. R.; Kirkpatrick, M.; Garcia, S. L.; Kellom, M.; McMahon, K. D.; Baker, B. J.

10.1101/2024.02.06.579087 — evolutionary biology — Posted on 2024-08-12

3153 Genetic properties underlying transcriptional variability across different perturbations

Tsuru, S.; Furusawa, C.

10.1101/2024.04.15.589659 — evolutionary biology — Posted on 2024-08-12

3154 Caspar specifies primordial germ cell count and identity in Drosophila melanogaster

Das, S.; Hegde, S.; Wagh, N.; Sudhakaran, J.; Roy, A. E.; Deshpande, G.; Ratnaparkhi, G. S.

10.1101/2024.04.25.591132 — developmental biology — Posted on 2024-08-12

3155 Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB

DeAngelo, J. D.; Maron, M. I.; Roth, J. S.; Silverstein, A. M.; Gupta, V.; Stransky, S.; Basken, J.; Azofeifa, J.; Sidoli, S.; Gamble, M. J.; Shechter, D.

10.1101/2024.08.09.607355 — molecular biology — Posted on 2024-08-12

3156 Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis

AHMAD, A.; Singh, R. B.; Nickolich, K.; Pilewski, M.; Ngeow, C.; Frempong-Manso, K.; Robinson, K. M.

10.1101/2024.07.01.601559 — immunology — Posted on 2024-08-12

3157 Environmental complexity modulates information processing and the balance between decision-making systems

Mugan, U.; Hoffman, S. L.; Redish, A. D.

10.1101/2024.03.11.584503 — neuroscience — Posted on 2024-08-12

3158 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality

Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.

10.1101/2023.02.24.529913 — biophysics — Posted on 2024-08-12

3159 Modeling the effects of vaccination against multiple strains of porcine reproductive and respiratory syndrome at the barn level

Kennedy, F.; Cardenas, N.; Galvis, J. A.; Corzo, C.; Machado, G.

10.1101/2024.08.06.606602 — ecology — Posted on 2024-08-12

3160 Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity

Cutler, R.; Corveleyn, L.; Ctortecka, C.; Cantlon, J.; Jacome Vaca, S. A.; Deforce, D.; Vijg, J.; Dhaenens, M.; Papanastasiou, M.; Carr, S. A.; Sidoli, S.

10.1101/2024.07.05.602213 — molecular biology — Posted on 2024-08-12

3161 A palette of bright and photostable monomeric fluorescent proteins for bacterial time-lapse imaging

Fraikin, N.; Couturier, A.; Lesterlin, C.

10.1101/2024.03.28.587235 — molecular biology — Posted on 2024-08-12

3162 A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall

Ramirez Carbo, C. A.; Faromiki, O. G.; Nan, B.

10.1101/2024.04.04.588103 — microbiology — Posted on 2024-08-12

3163 Agency accounts for the effect of feedback transparency on motor imagery neurofeedback performance

Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.

10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-08-12

3164 From Sensory to Perceptual Manifolds: The Twist of Neural Geometry

Ma, H.; Jiang, L.; Liu, T.; Liu, J.

10.1101/2023.10.02.559721 — neuroscience — Posted on 2024-08-12

3165 Delving into the claustrum: insights into memory formation, stabilization and updating in mice

Medina, C.; Ojea Ramos, S.; Depino, A. M.; Romano, A. G.; Krawczyk, M. C.; Boccia, M. M.

10.1101/2024.04.26.591314 — neuroscience — Posted on 2024-08-12

3166 Kinematic and neuromuscular characterization of cognitive involvement in gait control in healthy young adults

LANA, V.; FRERE, J.; CABIBEL, V.; REGUEME, T.; LEFEVRE, N.; Vlamynck, E.; DECKER, L. M.

10.1101/2022.07.01.498421 — neuroscience — Posted on 2024-08-12

3167 Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma

Shema, E.; Griess, O.; Furth, N.; Harpaz, N.; Di Bernardo, N.; Salame, T. M.; Dassa, B.; Karagiannidis, I.; Isshiki, Y.; Gross, M.; Melnick, A. M.; Beguelin, W.; Ron, G.

10.1101/2024.08.05.606629 — cancer biology — Posted on 2024-08-12

3168 Plasmonic Enhancement of Protein Function

Locarno, M.; Dong, Q.; Meng, X.; Glessi, C.; Hettema, N.; Brandsma, N.; Blokhuizen, S.; Castaneda, A.; Ganapathy, S.; Post, M.; Schmidt, T.; van Roemburg, L.; Xu, B.; Cho, C.-T.; Laan, L.; Chien, M.-P.; Brinks, D.

10.1101/2024.02.07.579195 — biophysics — Posted on 2024-08-12

3169 Harnessing Transformers to Generate Protein Sequences Prone to Liquid Liquid Phase Separation

Wasim, A.; Pramanik, U.; Das, A.; Latua, P.; Rudra, J.; Mondal, J.

10.1101/2024.03.02.583105 — biophysics — Posted on 2024-08-12

3170 Strategic acyl carrier protein engineering enables functional type II polyketide synthase reconstitution in vitro

Li, K. K.; Cho, Y. I.; Tran, M. A.; Wiedemann, C.; Zhang, S.; Koweek, R. S.; Hoang, N. K.; Hamrick, G.; Bowen, M.; Kokona, B.; Stallforth, P.; Beld, J.; Hellmich, U.; Charkoudian, L. K.

10.1101/2023.08.02.551649 — biochemistry — Posted on 2024-08-12

3171 Changes in the Public IgM Repertoire and its Idiotypic Connectivity in Alzheimer's Disease and Frontotemporal Dementia

Pashova-Dimov, S.; Petrov, P.; Karachanak-Yankova, S.; Belezhanska, D.; Zhelev, Y.; Mehrabian, S.; Traykov, L.; Pashov, A.

10.1101/2024.07.15.603559 — immunology — Posted on 2024-08-12

3172 CRISPRi-based screens in iAssembloids to elucidate neuron-glia interactions

Li, E.; Benitez, C.; Boggess, S. C.; Koontz, M.; Rose, I. V. L.; Martinez, D.; Draeger, N.; Teter, O. M.; Samelson, A. J.; Pierce, N.; Ullian, E. M.; Kampmann, M.

10.1101/2023.04.26.538498 — neuroscience — Posted on 2024-08-12

3173 Superiority of Rhythmic Auditory Signals over Electrical Stimulation to Entrain Behavior

Cabral-Calderin, Y.; Henry, M. J.

10.1101/2024.08.12.607618 — neuroscience — Posted on 2024-08-12

3174 Test-retest reliability of TMS motor evoked responses and silent periods during explosive voluntary isometric contractions.

Castelli, F.; Mian, O. S.; Bruton, A.; Chembila Valappil, A. C.; Hannah, R.; Tillin, N. A.

10.1101/2024.08.12.607577 — physiology — Posted on 2024-08-12

3175 Structural insight into binding site access and ligand recognition by human ABCB1

Kurre, D.; Dang, P. X.; Le, L. T. M.; Gadkari, V. V.; Alam, A.

10.1101/2024.08.12.607598 — biochemistry — Posted on 2024-08-12

3176 Scalable and universal prediction of cellular phenotypes

Ji, Y.; Tejada-Lapuerta, A.; Schmacke, N. A.; Zheng, Z.; Zhang, X.; Khan, S.; Rothenaigner, I.; Tschuck, J.; Hadian, K.; Theis, F. J.

10.1101/2024.08.12.607533 — cell biology — Posted on 2024-08-12

3177 Robust single nucleus RNA sequencing reveals depot-specific cell population dynamics in adipose tissue remodeling during obesity

So, J.; Strobel, O.; Wann, J.; Kim, K.; Paul, A.; Acri, D. J.; Dabin, L. C.; Peng, G.; Kim, J.; Roh, H.

10.1101/2024.04.08.588525 — molecular biology — Posted on 2024-08-12

3178 Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation

Marchetti, T.; Milanesi, S.; Tintor, D.; Lorenzini, T.; Walser, S.; Vavassori, S.; Boyman, O.; Pachlopnik Schmid, J.

10.1101/2024.08.12.607544 — immunology — Posted on 2024-08-12

3179 Causal dynamics of salience, default mode, and frontoparietal networks during episodic memory formation and recall: A multi-experiment iEEG replication

Das, A.; Menon, V.

10.1101/2024.02.28.582593 — neuroscience — Posted on 2024-08-12

3180 Composite impact of genome-wide APOBEC3-mediated mutations and HLA haplotype on cancer immunogenicity has a sex-biased survival impact

Borzooee, F.; Heravi-Moussavi, A.; Larijani, M.

10.1101/2024.08.07.607038 — cancer biology — Posted on 2024-08-12

3181 Nonlinear progression during the occult transition establishes cancer lethality

Ginzel, J. D.; Chapman, H.; Sills, J. E.; Allen, E. J.; Barak, L. S.; Cardiff, R. D.; Borowsky, A. D.; Lyerly, H. K.; Rogers, B. W.; Snyder, J. C.

10.1101/2024.04.23.590826 — cancer biology — Posted on 2024-08-12

3182 Deep Learning Driven Cell-Type-Specific Embedding for Inference of Single-Cell Co-expression Networks

Bai, Y.; Qian, K.; Lin, Q.; Fan, W.; Qin, R.; He, B.; Ding, F.; Liu, W.; Cui, P.

10.1101/2024.08.12.607542 — bioinformatics — Posted on 2024-08-12

3183 DNA polymerase Lambda is anchored within the NHEJ synaptic complex via Ku70/80

Chaplin, A. K.; Frit, P.; Calsou, P.; Amin, H.; Hall, C.; Zahid, S.; Barboule, N.; Matharu, G.; Hardwick, S. W.; Chirgadze, D. Y.; Chauvat, J.; Britton, S.; Ropars, V.; Charbonnier, J.-B.

10.1101/2024.08.12.607588 — biochemistry — Posted on 2024-08-12

3184 Experimental evolution of gene essentiality in bacteria

Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.

10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-08-12

3185 Golgi compaction facilitates microtubule nucleation to drive adult vertebrate peripheral neuron regeneration

Mortimer, A. E.; Reid, A. J.; Das, R. M.

10.1101/2024.08.12.607597 — cell biology — Posted on 2024-08-12

3186 Preclinical testing of RRx-001 in mouse models of experimental endometriosis reveals promising therapeutic impacts

McIntyre, I.; Vasilyev, V.; Perrone, C. L.; Dhami, P.; Panir, K.; Rosser, M.; Greaves, E.

10.1101/2024.08.12.607591 — immunology — Posted on 2024-08-12

3187 Causal Associations of Circulating Helicobacter pylori Antibodies with 5 Skin Disorders: A Mendelian Randomization Analysis

He, A.; Ni, Y.; Qiao, N.; Huang, W.; Gan, F.; Gong, Z.; Yang, X.; Zhao, X.

10.1101/2024.08.10.607427 — genomics — Posted on 2024-08-12

3188 Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High Fat Diet During Lactation

Mendoza-Romero, H. N.; Biddinger, J. E.; Bedenbaugh, M. N.; Simerly, R.

10.1101/2024.08.12.607566 — neuroscience — Posted on 2024-08-12

3189 Effects of excess dietary calcium supplementation during the transition phase on calcium and bone metabolism of dairy sheep and goats and growth response of their suckling offspring

Brugger, D.; Liesegang, A.

10.1101/2024.08.12.607180 — physiology — Posted on 2024-08-12

3190 Loss of PI5P4Kalpha slows the progression of a Pten mutant basal cell model of prostate cancer

Triscott, J.; Lehner, M.; Benjak, A.; Reist, M.; Emerling, B. M.; Ng, C. K.; de Brot, S.; Rubin, M. A.

10.1101/2024.08.12.607541 — cancer biology — Posted on 2024-08-12

3191 Therapeutic Tumor Macrophage Reprogramming in Breast Cancer Through a Peptide-Drug Conjugate

Lepland, A.; Peranzoni, E.; Haljasorg, U.; Asciutto, E. K.; Crespi-Amer, M.; Modesti, L.; Kilk, K.; Lombardia, M.; Acosta, G.; Royo, M.; Peterson, P.; Marigo, I.; Teesalu, T.; Scodeller, P.

10.1101/2024.08.12.607575 — cancer biology — Posted on 2024-08-12

3192 Exploring Transcriptional Regulation of Soybean Tissue Development with Machine Learning Method

Yang, Y.

10.1101/2024.08.12.607582 — bioinformatics — Posted on 2024-08-12

3193 Assessing the effect of model specification and prior sensitivity on Bayesian tests of temporal signal

Tay, J. H.; Kocher, A.; Duchene, S.

10.1101/2024.08.12.607579 — bioinformatics — Posted on 2024-08-12

3194 RIOT - Rapid Immunoglobulin Overview Tool - annotation of nucleotide and amino acid immunoglobulin sequences using an open germline database.

Dudzic, P.; Janusz, B.; Satlawa, T.; Chomicz, D.; Gawlowski, T.; Grabowski, R.; Jozwiak, P.; Tarkowski, M.; Mycielski, M.; Wrobel, S.; Krawczyk, K.

10.1101/2024.08.12.607568 — bioinformatics — Posted on 2024-08-12

3195 Results of the Protein Engineering Tournament: An Open Science Benchmark for Protein Modeling and Design

Armer, C.; Kane, H.; Cortade, D. L.; Redestig, H.; Estell, D. A.; Yusuf, A.; Rollins, N. J.; Spinner, H.; Marks, D.; Brunette, T.; Kelly, P. J.; DeBenedictis, E.

10.1101/2024.08.12.606135 — bioengineering — Posted on 2024-08-12

3196 Optimising the viscoelastic properties of hyaluronic acid hydrogels through colloidal particle interactions: a response surface methodology approach

Ramanathan, G.; Hassan, M.; Rochev, Y.

10.1101/2024.08.12.607572 — bioengineering — Posted on 2024-08-12

3197 Substrate Curvature Influences Cytoskeletal Rearrangement and Modulates Macrophage Phenotype

Sovar, A.; Patrick, M. D.; T. Annamalai, R.

10.1101/2024.08.12.607593 — bioengineering — Posted on 2024-08-12

3198 GroEL/ES chaperonin unfolds then encapsulates a nascent protein on the ribosome

Roeselova, A.; Maslen, S. L.; He, J. Z.; Jurkeviciute, G.; Skehel, M.; Enchev, R. I.; Balchin, D.

10.1101/2024.08.12.607569 — biochemistry — Posted on 2024-08-12

3199 Lower degree of microsatellite instability in colorectal carcinomas from MSH6-associated Lynch syndrome patients

Helderman, N. C.; Strobel, F.; Bohaumilitzky, L.; Terlouw, D.; van der Werf-'t Lam, A.-S.; van Wezel, T.; Morreau, H.; von Knebel Doeberitz, M.; Nielsen, M.; Kloor, M.; Ahadova, A.

10.1101/2024.08.12.607570 — genetics — Posted on 2024-08-12

3200 DNA-PKcs Inhibition Improves Sequential Gene Insertion of the Full-Length CFTR cDNA in Airway Stem Cells

Stack, J. T.; Rayner, R. E.; Nouri, R.; Suarez, C. J.; Kim, S. H.; Kanke, K. L.; Vetter, T. A.; Cormet-Boyaka, E.; Vaidyanathan, S.

10.1101/2024.08.12.607571 — genetics — Posted on 2024-08-12

3201 Genomic Evidence for Hybridization and Introgression in a North American Toad (Anaxyrus) Hybrid Zone

Cobb, K. A.; Oaks, J. R.

10.1101/2024.08.09.606439 — evolutionary biology — Posted on 2024-08-12

3202 Gut microbiome diversity associates with estimated lifetime and annual reproductive success in male but not female collared flycatchers

Liukkonen, M.; Gustafsson, L.; Grond, K.; Ruuskanen, S.

10.1101/2024.08.12.607561 — ecology — Posted on 2024-08-12

3203 Leveraging remote sensing to distinguish closely related beech species in assisted gene flow scenarios

Kaplan, G.; Mora, A.; Csillery, K.; Schuman, M. C.

10.1101/2024.08.12.607576 — ecology — Posted on 2024-08-12

3204 Listeria monocytogenes Requires Phosphotransferase Systems to Facilitate Intracellular Growth and Virulence

Freeman, M. J.; Sauer, J.-D.

10.1101/2024.08.12.607557 — microbiology — Posted on 2024-08-12

3205 E. coli phylogeny drives co-amoxiclav resistance through variable expression of blaTEM-1

Matlock, W.; Rodger, G.; Pritchard, E.; Colpus, M.; Kapel, N.; Barrett, L.; Morgan, M.; Oakley, S.; Hopkins, K. L.; Roohi, A.; Karageorgopoulos, D.; Avison, M. B.; Walker, A. S.; Lipworth, S.; Stoesser, N.

10.1101/2024.08.12.607562 — microbiology — Posted on 2024-08-12

3206 EEG-based analysis of intrinsic brain network function in chronic pain: Insights from a comprehensive multi-data set study

Bott, F. S.; Zebhauser, P. T.; Hohn, V. D.; Turgut, O.; May, E. S.; Tiemann, L.; Gil Avila, C.; Heitmann, H.; Nickel, M. M.; Day, M. A.; Adhia, D. B.; Ashar, Y. K.; Wager, T. D.; Granovsky, Y.; Yarnitsky, D.; Jensen, M. P.; Gross, J.; Ploner, M.

10.1101/2024.08.12.607584 — neuroscience — Posted on 2024-08-12

3207 Modelling inflammation-induced peripheral sensitization in a dish - more complex than expected?

Li, Y.; Lock, A.; Fedele, L.; Zebochin, I.; Sabate, A.; Siddle, M.; Cainarca, S.; Roederer, P.; Montag, K.; Tarroni, P.; Bruestle, O.; Shaw, T.; Taams, L.; Denk, F.

10.1101/2024.08.12.607558 — neuroscience — Posted on 2024-08-12

3208 The BDNF/TrkB pathway in Somatostatin-expressing neurons suppresses cocaine-seeking behaviour

Didio, G.; Aitta-Aho, T.; Umemori, J.; Castren, E.

10.1101/2024.08.12.607442 — neuroscience — Posted on 2024-08-12

3209 Mnemonic brain state engagement is diminished in healthy aging

Moore, I. L.; Smith, D. E.; Long, N. M.

10.1101/2024.08.12.607567 — neuroscience — Posted on 2024-08-12

3210 Longitudinal deformation based morphometry pipeline to study neuroanatomical differences in structural MRI based on SyN unbiased templates

Germann, J.; Venetucci Gouveia, F.; Chakravarty, M. M.; Devenyi, G. A.

10.1101/2024.08.12.607581 — neuroscience — Posted on 2024-08-12

3211 Attentional priority and limbic activity favor gains over losses

Hu, K.; De Rosa, E.; Anderson, A.

10.1101/2024.08.12.607518 — neuroscience — Posted on 2024-08-12

3212 Grape ripening speed slowed down using natural variation

Falginella, L.; Magris, G.; Castellarin, S. D.; Gambetta, G. A.; Matthews, M. A.; Morgante, M.; Di Gaspero, G.

10.1101/2024.08.12.607560 — plant biology — Posted on 2024-08-12

3213 Salicaceae endophyte inoculation alters stomatal patterning and improves the intrinsic water-use efficiency of Populus trichocarpa after a water-deficit.

Hendrickson, M.; Banan, D.; Tournay, R.; Bakker, J. D.; Doty, S.; Kim, S.-H.

10.1101/2024.08.10.607466 — plant biology — Posted on 2024-08-12

3214 Varietal screening of newly developed blackgram genotypes against Cercospora Leaf Spot (Cercospora canescens) in the Terai region of Nepal.

Shrestha, S.; Bohara, S.; Oli, S.; Nainabasti, A.; Bohara, K. R.; Upadhyaya, K.; Banet, I.

10.1101/2024.08.12.607552 — pathology — Posted on 2024-08-12

3215 SAFARI: Pangenome Alignment of Ancient DNA Using Purine/Pyrimidine Encodings

Rubin, J. D.; van Waaij, J.; Kraft, L. M.; Siren, J.; Sackett, P. W.; Renaud, G.

10.1101/2024.08.12.607489 — bioinformatics — Posted on 2024-08-12

3216 Machine Learning to Predict Gut Microbiomes of Agricultural Pests

Jobayer, M.; Taylor, A.; Hasan, M. R.; Ahmed, K. A.; Hossain, M. Z.

10.1101/2024.08.12.607564 — bioinformatics — Posted on 2024-08-12

3217 Allocating Limited Surveillance Effort for Outbreak Detection of Endemic Foot and Mouth Disease

Greiner, A.; Herrera-Diestra, J. L.; Tildesley, M.; Shea, K.; Ferrari, M.

10.1101/2024.08.12.607549 — ecology — Posted on 2024-08-12

3218 MRGM: An enhanced catalog of mouse gut microbial genomes substantially broadening taxonomic and functional landscapes

Kim, N.; Kim, C. Y.; Ma, J.; Yang, S.; Park, D.; Ha, S.-J.; Belenky, P.; Lee, I.

10.1101/2024.08.12.607507 — microbiology — Posted on 2024-08-12

3219 A fast-acting inhibitor of blood-stage P. falciparum with mechanism distinct from artemisinin and chloroquine

Kabeche, S.; Meister, T.; Yeh, E.

10.1101/2024.08.12.607553 — microbiology — Posted on 2024-08-12

3220 A genome-wide screen in ex vivo gallbladders identifies Listeria monocytogenes factors required for virulence in vivo

Schwardt, N. H.; Halsey, C. R.; Sanchez, M. E.; Reniere, M. L.

10.1101/2024.08.12.607554 — microbiology — Posted on 2024-08-12

3221 Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis

Wang, X.; Wang, J.; Li, N.; Fan, X.; Wang, B.

10.1101/2024.08.12.607555 — microbiology — Posted on 2024-08-12

3222 A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor

Walton, B.; Abbodante, S.; Marshall, M. E.; Dobruchowska, J. M.; Alvi, A.; Gallagher, L. A.; Vallikat, N.; Zhang, Z.; Wozniak, D. J.; Yu, E. W.; Boons, G.-J.; Pearlman, E.; Rietsch, A.

10.1101/2024.08.12.607380 — microbiology — Posted on 2024-08-12

3223 Cytokine-Induced Cell Exhaustion to Mitigate Hyperinflammation

Marchetti, T.; Milanesi, S.; Tintor, D.; Lorenzini, T.; Walser, S.; Vavassori, S.; Boyman, O.; Pachlopnik Schmid, J.

10.1101/2024.08.12.607544 — immunology — Posted on 2024-08-12

3224 The role of TRPV4 in acute sleep deprivation-induced fear memory impairment

Guo, M.; Zhang, F.; Liu, S.; Zhang, Y.; Wang, L.; Song, J.; Wei, W.; Li, X.

10.1101/2024.08.12.607531 — neuroscience — Posted on 2024-08-12

3225 Attentional modulation of secondary somatosensory and visual thalamus of mice

Petty, G.; Bruno, R. M.

10.1101/2024.03.22.586242 — neuroscience — Posted on 2024-08-12

3226 A posture subspace in primary motor cortex

Marino, P. J.; Bahureksa, L.; Fernandez Fisac, C.; Oby, E. R.; Smoulder, A. L.; Motiwala, A.; Degenhart, A. D.; Grigsby, E. M.; Joiner, W. M.; Chase, S. M.; Yu, B. M.; Batista, A. P.

10.1101/2024.08.12.607361 — neuroscience — Posted on 2024-08-12

3227 4D hybrid model interrogates agent-level rules and parameters driving hiPS cell colony dynamics

Yu, J. S.; Lyons, B.; Rafelski, S. M.; Theriot, J. A.; Bagheri, N.; Johnson, G.

10.1101/2024.08.12.607546 — systems biology — Posted on 2024-08-12

3228 Endoplasmic reticulum stress inhibition preserves mitochondrial function and cell survival during early onset of isoniazid-induced oxidative stress

Nhung, T. T. M.; Phat, N. K.; Anh, T. T.; Nghi, T. D.; Thu, N. Q.; Lee, A.; Tien, N. T. N.; Anh, N. K.; Kim, K.; Nguyen, D. N.; Kim, D. H.; Park, S. K.; Long, N. P.

10.1101/2024.08.12.607527 — pharmacology and toxicology — Posted on 2024-08-12

3229 Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukaemia.

Lewis, A. C.; Gruber, E.; Franich, R.; Armstrong, J.; Kelly, M. J.; Opazo, C. M.; Mawal, C. H.; Birrell, A.; So, J.; Ting, K.; Brown, F.; Wei, A. H.; Powell, J. A.; Brown, K. K.; Johnstone, R. W.; Kats, L. M.

10.1101/2024.08.11.607520 — cancer biology — Posted on 2024-08-12

3230 Fast and Accurate LSTM Meta-modeling of TNF-induced Tumor Resistance In Vitro

Abrate, M. P.; Smeriglio, R.; Bardini, R.; Savino, A.; Di Carlo, S.

10.1101/2024.08.12.607535 — bioinformatics — Posted on 2024-08-12

3231 Investigating the impact of edge weight selection on the pig trade network topology

Puspitarani, G. A.; Liao, Y.-S. J.; Fuchs, R.; Desvars-Larrive, A.

10.1101/2024.08.12.607545 — bioinformatics — Posted on 2024-08-12

3232 Deciphering BRCAness Phenotype in Cancer: A Graph Convolutional Neural Network Approach with Layer-wise Relevance Propagation Analysis

Yang, J.; Chereda, H.; Dönitz, J.; Bleckmann, A.; Beissbarth, T.

10.1101/2024.06.26.600328 — bioinformatics — Posted on 2024-08-12

3233 HSV-1 infection induces a downstream-shift of the +1 nucleosome

Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.

10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-08-12

3234 A Human Brain-Chip for modelling brain pathologies and screening of BBB crossing therapeutic strategies

Chim, S. M.; Howell, K.; Kokkosis, A.; Zambrowicz, B.; Karalis, K.; Pavlopoulos, E.

10.1101/2024.08.11.607509 — bioengineering — Posted on 2024-08-12

3235 Multi-Targeted Effects of Novel Cycloastragenol Derivatives: Enhancing NRF2, Proteostasis, and Telomerase Pathways with p53 Modulation to Delay Replicative Senescence

Yilmaz, S.; Bedir, E.; Ballar Kirmizibayrak, P.

10.1101/2024.08.12.607434 — biochemistry — Posted on 2024-08-12

3236 Examining NFκB Genomic Interactions by ChIP-seq and CUT&Tag

Daly, A. E.; Schiffman, A.; Hoffmann, A.; Smale, S.

10.1101/2024.08.11.607521 — genomics — Posted on 2024-08-12

3237 OzWheat: a genome-to-phenome platform to resolve complex traits for wheat pre-breeding and research.

Hyles, J. E.; Eagles, H. A.; Ramm, K.; Sherman, B.; Gock, A.; Stops, S.; Phongkham, T.; Leyne, E.; Rathjen, T.; Suchecki, R.; Stevens, L. E.; Ord, L.; Fradgley, N. S.; McNeil, M. D.; Marquardt, A.; Andrew, S. C.; Forrest, K.; Eastwood, R. F.; Norman, A.; Tredrea, A.; Trethowan, R.; Trevaskis, B.; Dillon, S. K.

10.1101/2024.08.11.603522 — genomics — Posted on 2024-08-12

3238 Exploring adaptive introgression in modern human circadian rhythm genes

Kendall, C.; Nooranikhojasteh, A.; Debortoli, G.; Caue Furlan Roberto, V.; Mendes, M.; Samson, D.; Parra, E.; Viola, B.; Schillaci, M.

10.1101/2024.08.12.607550 — genomics — Posted on 2024-08-12

3239 Molecular phylogenetics illuminates evolutionary history and hidden diversity of Australian cave crickets (Orthoptera: Rhaphidophoridae)

Beasley-Hall, P. G.; Trewick, S. A.; Eberhard, S. M.; Zwick, A.; Reed, E. H.; Cooper, S. J. B.; Austin, A. D.

10.1101/2024.08.11.607522 — evolutionary biology — Posted on 2024-08-12

3240 Recurrent sex chromosome turn-over in termites

Fraser, R.; Moraa, R.; Djolai, A.; Meisenheimer, N.; Laube, S.; Vicoso, B.; Huylmans, A. K.

10.1101/2024.08.12.607539 — evolutionary biology — Posted on 2024-08-12

3241 Diverse somatic Transformer and sex chromosome karyotype pathways regulate gene expression in Drosophila gonad development

Mahadevaraju, S.; Pal, S.; Bhaskar, P.; McDonald, B.; Benner, L.; Denti, L.; Cozzi, D.; Bonizzoni, P.; Przytycka, T.; Oliver, B.

10.1101/2024.08.12.607556 — developmental biology — Posted on 2024-08-12

3242 The primary sclerosing cholangitis and ulcerative colitis colonic mucosa defined through paired microbial and single-cell RNA sequencing

Tearle, J. L. E.; Zhang, F.; Jackson, K. J. L.; Malhotra, P.; Tavakoli, P.; Koentgen, S.; Warren, J.; Williams, C.; Haque, A.; Arzivian, A.; Tedla, N.; Kim, A.; King, H. W.; Hold, G. L.; Ghaly, S.; James, K. R.

10.1101/2024.08.12.607536 — cell biology — Posted on 2024-08-12

3243 Immunotherapeutic strategy to prevent progression and complications of acute rheumatic fever

Lepletier, A.; Rafeek, R. A. M.; Ketheesan, N.; Good, M. F.; Pandey, M.

10.1101/2024.08.11.607519 — immunology — Posted on 2024-08-12

3244 Perceived multisensory common cause relations shape the ventriloquism effect but only marginally the trial-wise aftereffect

Kayser, C.; Heuer, H.

10.1101/2024.08.12.607537 — neuroscience — Posted on 2024-08-12

3245 Time Makes Space: Emergence of Place Fields in Networks Encoding Temporally Continuous Sensory Experiences

Wang, Z.; Di Tullio, R. W.; Rooke, S.; Balasubramanian, V.

10.1101/2024.08.11.607484 — neuroscience — Posted on 2024-08-12

3246 Brain-like border ownership signals support prediction of natural videos

Ye, Z.; Wessel, R.; Franken, T. P.

10.1101/2024.08.11.607040 — neuroscience — Posted on 2024-08-12

3247 Serpina1e mediates the exercise-induced enhancement of hippocampal memory

Kim, H.; Shin, S.; Kim, J.-S.; Park, H.

10.1101/2024.08.11.607526 — neuroscience — Posted on 2024-08-12

3248 Local Synthesis of Reticulon-1C Lessens the Outgrowth of Injured Axons by Controlling Spastin Activity

Luarte, A.; Gallardo, J.; Corvalan, D.; Chakraborty, A.; Gouveia-Roque, C.; Bertin, F.; Contreras, C.; Ramirez, J. P.; Weber, A.; Acevedo, W.; Zuschratter, W.; Herrera, R.; Wyneken, U.; Paula Lima, A.; Adasme, T.; Figueroa, A.; Gonzalez, C.; Gonzalez-Billault, C.; Hengst, U.; Couve, A.

10.1101/2024.08.11.607514 — neuroscience — Posted on 2024-08-12

3249 Efficient modular system identification provides a high-resolution assay of temporal processing and reveals the multilevel effects of attention along the human auditory pathway

Singh, R.; Bharadwaj, H.

10.1101/2024.08.11.607503 — neuroscience — Posted on 2024-08-12

3250 Subsets of extraocular motoneurons produce kinematically distinct saccades during hunting and exploration.

Dowell, C. K.; Hawkins, T.; Bianco, I. H.

10.1101/2024.08.12.607184 — neuroscience — Posted on 2024-08-12

3251 Functional Electrical Stimulation and Brain-Machine Interfaces for Simultaneous Control of Wrist and Finger Flexion

Mender, M. J.; Ward, A. L.; Cubillos, L. H.; Kelberman, M. M.; Costello, J. T.; Temmar, H.; Wallace, D. M.; Lin, E. T.; Lam, J. L. W.; Willsey, M. S.; Ganesh Kumar, N.; Kung, T. A.; Patil, P. G.; Chestek, C. A.

10.1101/2024.08.11.607263 — neuroscience — Posted on 2024-08-12

3252 Mathematical Modeling of Impacts of Patient Differences on Renin-Angiotensin System and Applications to COVID-19 Lung Fibrosis Outcomes

Islam, M. A.; Ford Versypt, A. N.

10.1101/2022.11.06.515367 — systems biology — Posted on 2024-08-12

3253 Unraveling lncRNA Diversity at a Single Cell Resolution and in a Spatial Context across Different Cancer Types

Prakrithi, P.; Vo, T.; Vu, H.; Xiong, A.; Nguyen, L. T.; Newman, A.; Whitehall, V.; Gonzalez Cruz, J. L.; Gupta, I.; Nguyen, Q.

10.1101/2024.08.12.607523 — cancer biology — Posted on 2024-08-12

3254 Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation

Lawrence, E.; Cooray, A.; Kueh, A.; Pal, M.; Tai, L.; Garnham, A.; Li-Wai-Suen, C. S. N.; Vanyai, H.; Gouil, Q.; Lancaster, J.; Callegari, S.; Whelan, L.; Lieschke, E.; Thomas, A.; Strasser, A.; Liao, Y.; Shi, W.; Wei, A.; Herold, M. J.

10.1101/2024.08.12.607467 — cancer biology — Posted on 2024-08-12

3255 Ferroptosis susceptibility of melanoma cells: dependence on cell-type, acquired drug resistance, and medium composition

Preis, J. R.; Rolvering, C.; Kirchmeyer, M.; Halilovic, D.; Wroblewska, J. P.; Tolle, F.; Behrmann, I.; Haan, C.

10.1101/2024.08.12.607529 — cancer biology — Posted on 2024-08-12

3256 Interpretable improving prediction performance of general protein language model by domain-adaptive pretraining on DNA-binding protein

Zeng, W.; Dou, Y.; Pan, L.; Xu, L.; Peng, S.

10.1101/2024.08.11.607410 — bioinformatics — Posted on 2024-08-12

3257 CaMutQC: An R Package for Integrative Quality Control of Cancer Somatic Mutations

Wang, X.; Jiang, T.; Shen, A.; Chen, Y.; Zhou, Y.; Liu, J.; Zhao, S.; Chen, S.; Ren, J.; Zhao, Q.

10.1101/2024.08.12.606123 — bioinformatics — Posted on 2024-08-12

3258 Hydrogel injection molded complex macroencapsulation device geometry improves long-term cell therapy viability and function in the rat omentum transplant site

Emerson, A. E.; Lyons, Q.; Becker, M. W.; Sepulveda, K.; Hiremath, S. C.; Brady, S. R.; Weaver, J. D.

10.1101/2024.08.11.607495 — bioengineering — Posted on 2024-08-12

3259 Identification of a novel resistance gene which provides insight into Vip3Aa mode of action in Helicoverpa armigera

Bachler, A.; Padovan, A.; Anderson, C. J.; Wei, Y.; Wu, Y.; Pearce, S.; Downes, S.; James, B.; Tessnow, A.; Sword, G. A.; Williams, M.; Tay, W. T.; Gordon, K. H. J.; Walsh, T. K.

10.1101/2024.08.11.607516 — genomics — Posted on 2024-08-12

3260 Ecosystem dynamics in wet heathlands: spatial and temporal effects of environmental drivers on the vegetation

Damgaard, C.

10.1101/2024.08.06.606794 — ecology — Posted on 2024-08-12

3261 Ribosomal L12 stalks recruit elongation factors to speed protein synthesis in Escherichia coli

Hofmann, J. L.; Yang, T. S.; Sunol, A. M.; Zia, R. N.

10.1101/2023.04.14.536948 — biophysics — Posted on 2024-08-12

3262 Modeling collagen fibril degradation as a function of matrix microarchitecture

Debnath, B.; Narasimhan, B. N.; Fraley, S. I.; Rangamani, P.

10.1101/2024.08.10.607470 — biophysics — Posted on 2024-08-12

3263 Incoherent collective cell chemotaxis underlies organ dysmorphia in a model of branchio-oto-renal syndrome

Borges, A.; Pinto Teixeira, F.; Wibowo, I.; Hammerschmidt, M.; Kawakami, K.; Miranda Rodriguez, J. R.; Lopez-Schier, H.

10.1101/2021.01.27.428404 — developmental biology — Posted on 2024-08-12

3264 Scalable and universal prediction of cellular phenotypes

Ji, Y.; Tejada-Lapuerta, A.; Schmacke, N. A.; Zheng, Z.; Zhang, X.; Khan, S.; Rothenaigner, I.; Tschuck, J.; Hadian, K.; Theis, F. J.

10.1101/2024.08.12.607533 — cell biology — Posted on 2024-08-12

3265 Variable rRNA 2'-O-methylation fine-tunes ribosome function in Saccharomyces cerevisiae

Gillot, S.; Marchand, V.; Motorin, Y.; Baudin-Baillieu, A.; Namy, O.

10.1101/2024.08.07.607065 — molecular biology — Posted on 2024-08-12

3266 YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges

Shi, Z.; Wen, K.; Zou, Z.; Fu, W.; Guo, K.; Sammudin, N. H.; Ruan, X.; Sullere, S.; Wang, S.; Zhang, X.; Thinakaran, G.; He, C.; Zhuang, X.

10.1101/2024.08.07.607063 — neuroscience — Posted on 2024-08-12

3267 When visual attention is divided in the flash-lag effect

Yook, J.; Hogendoorn, H.; Fink, G. R.; Vossel, S.; Weidner, R.

10.1101/2024.03.14.585092 — neuroscience — Posted on 2024-08-12

3268 T-Cell-Mediated Killing in Glioblastoma Organoids induced by Adenoviral Delivery of the CIITA Transgene

Salvato, I.; Klein, E.; Poli, A.; Rezaeipour, M.; Ermini, L.; Nosirov, B.; Lipsa, A.; Oudin, A.; Baus, V.; Dore, G. M.; Cosma, A.; Golebiewska, A.; Marchini, A.; Niclou, S. P.

10.1101/2024.01.22.576747 — cancer biology — Posted on 2024-08-12

3269 MP-GNN: Graph Neural Networks to Identify MoonlightingProteins

Zhou, H.; Sarkar, R.

10.1101/2023.11.13.566879 — bioinformatics — Posted on 2024-08-12

3270 Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs

Garcia Guerra, A.; Sathyaprakash, C.; de Jong, O. G.; Lim, W.; Vader, P.; EL Andaloussi, S.; Bath, J.; Reine, J.; Aoki, Y.; Turberfield, A.; Wood, M.; Rinaldi, C.

10.1101/2024.08.09.605335 — bioengineering — Posted on 2024-08-12

3271 Dynamic medial parietal and hippocampal deactivations under DMT relate to sympathetic output and altered sense of time, space, and the self

Pasquini, L.; Simon, A.; Gallen, C.; Kettner, H.; Roseman, L.; Gazzaley, A.; Carhart-Harris, R.; Timmermann, C.

10.1101/2024.02.14.580356 — neuroscience — Posted on 2024-08-12

3272 Delineating In-Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI

Dalby, C.; Dibble, A. J.; Carvalheiro, J.; Queirazza, F.; Sevegnani, M.; Harvey, M.; Svanera, M.; Fracasso, A.

10.1101/2024.08.05.605123 — neuroscience — Posted on 2024-08-12

3273 Surface lipids in nematodes are developmentally dependent and species-specific

Kotowska, A. M.; Hiramatsu, F.; Alexander, M. R.; Scurr, D. J.; Lightfoot, J. W.; Chauhan, V. M.

10.1101/2024.04.24.590549 — systems biology — Posted on 2024-08-12

3274 Sexually antagonistic co-evolution can explain female display signals and male sensory adaptations.

Wiberg, R. A. W.; Murray, R. L.; Herridge, E.; Parssinen, V.; Gwynne, D. T.; Bussiere, L. F.

10.1101/2022.03.14.484300 — evolutionary biology — Posted on 2024-08-12

3275 Evidence for deliberate burial of the dead by Homo naledi

Berger, L. R.; Makhubela, T.; Molopyane, K.; Kruger, A.; Randolph-Quinney, P.; Elliott, M.; Peixotto, B.; Fuentes, A.; Tafforeau, P.; Beyrand, V.; Dollman, K.; Jinnah, Z.; Brewer Gillham, A.; Broad, K.; Brophy, J.; Chinamatira, G.; Dirks, P.; Feuerriegel, E.; Gurtov, A.; Hlophe, N.; Hunter, L.; Hunte, R.; Jakata, K.; Jaskolski, C.; Morris, H.; Pryor, E.; Ramaphela, M.; Roberts, E.; Smilg, J.; Tsikoane, M.; Tucker, S.; van Rooyen, D.; Warren, K.; Wren, C.; Kissel, M.; Spikins, P.; Hawks, J.

10.1101/2023.06.01.543127 — paleontology — Posted on 2024-08-12

3276 Effect of diffusivity of amyloid beta monomers on the formation of senile plaques

Kuznetsov, A. V.

10.1101/2023.07.31.551367 — biophysics — Posted on 2024-08-11

3277 Growth regulation bringing modularity to morphogenesis of complex three-dimensional exoskeletons

Ito, H. C.; Uchiumi, Y.

10.1101/2024.05.06.592547 — developmental biology — Posted on 2024-08-11

3278 Prefrontal Cortex subregions provide distinct visual and behavioral feedback modulation to the Primary Visual Cortex

Ährlund-Richter, S.; Osako, Y.; Jenks, K. R.; Odom, E.; Huang, H.; Arnold, D. B.; Sur, M.

10.1101/2024.08.06.606894 — neuroscience — Posted on 2024-08-11

3279 Formation of brain-wide neural geometry during visual item recognition in monkeys

Chen, H.; Kunimatsu, J.; Oya, T.; Imaizumi, Y.; Hori, Y.; Matsumoto, M.; Tsubo, Y.; Hikosaka, O.; Minamimoto, T.; Naya, Y.; Yamada, H.

10.1101/2024.08.05.604527 — neuroscience — Posted on 2024-08-11

3280 Relative phase of distributed oscillatory dynamics implements a working memory in a simple brain

Dunn, R. L.; Costello, C.; Borchardt, J. M.; Sprague, D. Y.; Chiu, G. C.; Miller, J. M.; L'Etoile, N.; Kato, S.

10.1101/2024.08.11.607402 — neuroscience — Posted on 2024-08-11

3281 A hierarchy of metabolite exchanges in metabolic models of microbial species and communities

Wedmark, Y. K.; Vik, J. O.; Oyas, O.

10.1101/2023.09.05.556413 — systems biology — Posted on 2024-08-11

3282 Prevalence and associated risk factors assessment of bovine fasciolosis in and around Bahir Dar, Ethiopia

Temesgen, A. B.; Mesfin, T.

10.1101/2024.08.07.606800 — pathology — Posted on 2024-08-11

3283 A novel visual analysis interface enables integrative analyses of cancer transcriptomics data and iden-tifies potential markers of immunotherapy response via machine learning.

Kus, M. E.; Sahin, C.; Kilic, E.; Askin, A.; Ozgur, M. M.; Karahanogullari, G.; Aksit, A.; O'Connell, R. M.; Ekiz, H. A.

10.1101/2023.08.14.553075 — bioinformatics — Posted on 2024-08-11

3284 Detecting Rhythmic Gene Expression in Single Cell Transcriptomics

Xu, B.; Ma, D.; Abruzzi, K.; Braun, R.

10.1101/2023.12.07.570691 — bioinformatics — Posted on 2024-08-11

3285 MMCCI: multimodal integrative analysis of single-cell and spatial cell-type communications to uncover overarching and condition-specific ligand-receptor interaction pathways

Hockey, L.; Mulay, O.; Xiong, Z.; Tan, S. X.; Khosrotehrani, K.; Nefzger, C. M.; Nguyen, Q.

10.1101/2024.02.28.582639 — bioinformatics — Posted on 2024-08-11

3286 A framework for quality control in quantitative proteomics

Tsantilas, K. A.; Merrihew, G. E.; Robbins, J. E.; Johnson, R. S.; Park, J.; Plubell, D. L.; Canterbury, J. D.; Huang, E.; Riffle, M.; Sharma, V.; MacLean, B. X.; Eckels, J.; Wu, C. C.; Bereman, M. S.; Spencer, S. E.; Hoofnagle, A. N.; MacCoss, M. J.

10.1101/2024.04.12.589318 — biochemistry — Posted on 2024-08-11

3287 Methods for detection of cardiac glycogen-autophagy

Koutsifeli, P.; Daniels, L. J.; Neale, J. P. H.; Fong, S.; Varma, U.; Annandale, M.; Li, X.; Nursalim, Y.; Bell, J. R.; Weeks, K. L.; Stotland, A.; Taylor, D. J.; Gottlieb, R. A.; Delbridge, L. M. D.; Mellor, K. M.

10.1101/2024.08.11.607511 — molecular biology — Posted on 2024-08-11

3288 AmygdalaGo-BOLT3D: A boundary learning transformer for tracing human amygdala

Dong, B.; Zhou, Q.; Gao, P.; Jintao, W.; Xiao, J.; Wang, W.; Liang, P.; Lin, D.; He, H.; Zuo, X.-N.

10.1101/2024.08.11.607487 — neuroscience — Posted on 2024-08-11

3289 Modeling Microbial Regulatory Feedback in Organic Matter Decomposition Identifies Copiotrophic Traits as Key Drivers of Positive Priming

Ahamed, F.; Stegen, J. C.; Graham, E. B.; Scheibe, T. D.; Song, H.-S.

10.1101/2024.08.11.607483 — systems biology — Posted on 2024-08-11

3290 A Self-Assembling Immune-Featured Osteosarcoma Patient/PDX Derived Organoid Model and Biobank for Personalized Immune Therapy

Mu, H.; Tao, Y.; Wang, J.; He, X.; Zhang, Q.; Chen, W.; Yao, B.; Ding, S.; Yang, X.; Zhang, L.; Wang, H.; Zuo, D.; Shen, J.; Sun, M.; Wang, H.; Jiao, M.; Jin, X.; Jin, Y.; Liang, Y.; Gong, Y.; Mao, W.; Liu, Q.; Wang, Z.; Lv, Y.; Xu, J.; Zhang, T.; Yang, Y.; Lin, J.; Asward, F. J.; Joseph, J. D.; Li, M.; Cai, Z.; Sun, W.; Yang, L.; Hua, Y.

10.1101/2024.08.11.607471 — cancer biology — Posted on 2024-08-11

3291 Faster amylin aggregation on fibrillar collagen hastens diabetic progression through β cell death and loss of function

Hazari, M. A.; Kannan, G.; Jha, A. K.; Pavan, M. K.; Dasgupta, S.; Sultana, F.; Pujahari, S. R.; Singh, S.; Dutta, S.; Pydi, S. P.; Dutta, S.; Bhaumik, P.; Zafar, H.; Kumar, A.; Sen, S.

10.1101/2024.08.10.607320 — biophysics — Posted on 2024-08-11

3292 Oligomerization-Mediated Phase-Separation in the Nucleoid-Associated Sensory Protein H-NS is Controlled by Ambient Cues

Lukose, B.; Goyal, S.; Naganathan, A. N.

10.1101/2024.08.10.607472 — biophysics — Posted on 2024-08-11

3293 Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity

Coupe, S. T.; Fakhri, N.

10.1101/2024.08.11.607499 — biophysics — Posted on 2024-08-11

3294 Predicting the translation efficiency of messenger RNA in mammalian cells

Zheng, D.; Wang, J.; Persyn, L.; Liu, Y.; Montoya, F. U.; Cenik, C.; Agarwal, V.

10.1101/2024.08.11.607362 — bioinformatics — Posted on 2024-08-11

3295 Translation efficiency covariation across cell types is a conserved organizing principle of mammalian transcriptomes

Liu, Y.; Hoskins, I.; Geng, M.; Zhao, Q.; Chacko, J.; Qi, K.; Persyn, L.; Wang, J.; Zheng, D.; Zhong, Y.; Rao, S.; Park, D.; Cenik, E. S.; Agarwal, V.; Ozadam, H.; Cenik, C.

10.1101/2024.08.11.607360 — bioinformatics — Posted on 2024-08-11

3296 Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling

Mcleod, J. C.; Lim, C.; Stokes, T.; Sharif, J.-A.; Zeynalli, V.; Wiens, L.; D'Souza, A. C.; Colenso-Semple, L.; McKendry, J.; Morton, R. W.; Mitchell, C. J.; Oikawa, S. Y.; Wahlestedt, C.; Chapple, P.; McGlory, C.; Timmons, J. A.; Phillips, S. M.

10.1101/2024.08.11.606848 — bioinformatics — Posted on 2024-08-11

3297 3D printed microtissue cassettes enabling high throughput proton radiobiological assays

Yang, C.-T.; Cho, I.-C.; Yu, C.-F.; Cheah, E.; Liu, T.; Lin, Y.-P.; Yu, S.; Jheng, J.-W.; Kempson, I.; Chao, T.-C.; Lee, S.-H.; Bezak, E.; Thierry, B.

10.1101/2024.08.10.607473 — bioengineering — Posted on 2024-08-11

3298 Characterization of a marine bacteria through a novel metabologenomics approach

Arini, G.; Borelli, T. C.; Ferreira, E. G.; de Felicio, R.; Rezende-Teixeira, P.; Goncalves, M. P.; Oliveira, F. R.; de Siqueira, G. V.; Mencucini, L. G.; Tsuji, H.; Andrade, L. S. N.; Garrido, L.; Padilla, G.; Gil-de-la-Fuentes, A.; Wang, M.; Lopes, N. P.; Trivella, D. B.; Costa-Lotufo, L. V.; Guazzaroni, M.-E.; da Silva, R. R.

10.1101/2024.08.11.607463 — biochemistry — Posted on 2024-08-11

3299 Mechanism of Co-Transcriptional Cap-Snatching by Influenza Polymerase

Rotsch, A. H.; Li, D.; Dupont, M.; Krischuns, T.; Oberthuer, C.; Stelfox, A.; Lukarska, M.; Fianu, I.; Lidschreiber, M.; Naffakh, N.; Dienemann, C.; Cusack, S.; Cramer, P.

10.1101/2024.08.11.607481 — biochemistry — Posted on 2024-08-11

3300 Exploiting functional regions in the viral RNA genome as druggable entities

Wei, D.; Luo, D.; Zheng, Y.; Huang, Z.; Wen, Z.; Guo, L.; Deng, Y.; Li, Q.; Bai, Y.; Haider, S.; Parkinson, G. N.

10.1101/2024.08.11.607475 — genomics — Posted on 2024-08-11

3301 High-resolution global diversity copy number variation maps and association with ctyper

Chaisson, M.; Ma, W.

10.1101/2024.08.11.607269 — genomics — Posted on 2024-08-11

3302 Adversarial learning enables unbiased organism-wide cross-species alignment of single-cell RNA data

Cooper, S.; Diaz-Mejia, J. J.; Innes, B.; Williams, E.; Mendonca, D.; Focsa, O.; Nixon, A.; Singh, S.; Schuster, R.; Hinz, B.; Buechler, M.

10.1101/2024.08.11.607498 — genetics — Posted on 2024-08-11

3303 Continuous emergence of phototaxis in Dictyostelium discoideum

Genettais, D.; Bernard, C.; Geoffroy, F.; Nizak, C.; Adiba, S.

10.1101/2024.08.11.607478 — evolutionary biology — Posted on 2024-08-11

3304 Environmental DNA Surveys of Invertebrate Community on Forest Canopies Using Rainwater Analysis

Miwa, T.; Miyashita, N.; Numa, C.; Doi, H.

10.1101/2024.08.11.607477 — ecology — Posted on 2024-08-11

3305 Ultra-low photodamage three-photon microscopy assisted by neural network for monitoring regenerative myogenesis

Li, Y.; Li, k.; He, M.; Liang, C.; Xie, X.; Qian, J.

10.1101/2024.08.11.607469 — developmental biology — Posted on 2024-08-11

3306 Rapid depletion and super-resolution microscopy reveal an unexpected role of the nuclear-speckle protein SRSF5 in paraspeckle assembly and dynamics during cellular stress

Arnold, B.; Kessler, L.; Okuda, E. K.; Rieger, R. R.; Canas, M. C. H.; Zebrowska, E.; Bakisoglu, C.; Nagasse, H. Y.; Stanek, D.; Dormann, D.; Zarnack, K.; Heilemann, M.; Mueller-McNicoll, M.

10.1101/2024.08.11.607506 — cell biology — Posted on 2024-08-11

3307 PPARγ activation by lipolysis-generated ligands is required for cAMP dependent UCP1 induction in human thermogenic adipocytes

Desai, A.; Yang Loureiro, Z.; DeSouza, T.; Yang, Q.; Solivan-Rivera, J.; Corvera, S.

10.1101/2024.08.10.607465 — cell biology — Posted on 2024-08-11

3308 An aberrant protamine ratio is associated with decreased H4ac levels in murine and human sperm

Kruse, A.; Schneider, S.; Merges, G. E.; Froebius, A. C.; Forne, I.; Imhof, A.; Schorle, H.; Steger, K.

10.1101/2024.08.11.606797 — molecular biology — Posted on 2024-08-11

3309 B cells targeting parasites capture spatially linked antigens to secure T cell help

Gao, X.; McNamara, H. A.; Lee, J.; Lo, A. F.; Chatterjee, D.; Spensberger, D.; Fernandez-Ruiz, D.; Walz, K.; Wang, K.; Kelly, H. G.; Pohl, K.; Carreira, P. E.; Do, A.; Xiong, L.; Beattie, L.; Spencer, A. J.; Gray, D. H.; Frischknecht, F.; Rug, M.; Cockburn, I. A.

10.1101/2024.08.10.607257 — immunology — Posted on 2024-08-11

3310 Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signalling

Xu, C.; Obers, A.; Qin, M.; Brandli, A.; Wong, J.; Huang, X.; Clatch, A.; Fayed, A.; Starkey, G.; DCosta, R.; Gordon, C. L.; Beattie, L.; Mackay, L. K.; Godfrey, D. I.; Koay, H.-F.

10.1101/2024.08.11.607476 — immunology — Posted on 2024-08-11

3311 EMMPRIN confers metabolic advantage for monocytes and macrophages to promote disease in a model of multiple sclerosis

Kaushik, D.; Das, A.; Silva, C.; D'Mello, C.; Almeida, L. G. N.; Ghasemi, N.; Neri, P.; Dufour, A.; Bahlis, N. J.; Xue, M.; Yong, V. W.

10.1101/2024.08.11.607460 — immunology — Posted on 2024-08-11

3312 Neural Sequences Underlying Directed Turning in C. elegans

Kramer, T. S.; Wan, F. K.; Pugliese, S. M.; Atanas, A. A.; Hiser, A. W.; Luo, J.; Bueno, E.; Flavell, S. W.

10.1101/2024.08.11.607076 — neuroscience — Posted on 2024-08-11

3313 Early life challenge enhances cortisol regulation in zebrafish larvae

Castillo-Ramirez, L. A.; Herget, U.; Ryu, S.; De Marco, R. J.

10.1101/2024.08.11.607500 — physiology — Posted on 2024-08-11

3314 Neural Mechanism Underlying Successful Classification of Amnestic Mild Cognitive Impairment Using Multi-Sensory-Evoked Potentials

Zhang, L.; Binns, M.; Chow, R.; Rabi, R.; Anderson, N. D.; Lu, J.; Freedman, M.; Alain, C.

10.1101/2024.08.10.607449 — neuroscience — Posted on 2024-08-11

3315 Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer

wang, Y.

10.1101/2024.08.07.606975 — bioinformatics — Posted on 2024-08-11

3316 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D

Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.

10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-08-11

3317 The chromokinesin Kid (KIF22) forms a homodimer, moves processively along microtubules and transports double-strand DNA

Niwa, S.; Furusaki, N.; Kita, T.; Chiba, K.

10.1101/2024.03.13.584902 — biochemistry — Posted on 2024-08-11

3318 Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via Hippo-YAP/TAZ and Notch signal pathway

Isotani, R.; Igarashi, M.; Miura, M.; Naruse, K.; Kuranami, S.; Katoh, M.; Nomura, S.; Yamauchi, T.

10.1101/2024.01.02.573853 — cell biology — Posted on 2024-08-11

3319 Dysregulation of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion

wu, h.

10.1101/2024.02.28.582462 — microbiology — Posted on 2024-08-11

3320 TFEB-Mediated Pro-inflammatory Response in Murine Macrophages Induced by Acute Alpha7 Nicotinic Receptor Activation

Honwad, H. H.; Najibi, M.; Koscso, B.; Bogunovic, M.; Irazoqui, J. E.

10.1101/2024.01.26.577408 — immunology — Posted on 2024-08-10

3321 Reward history cues focal attention in whisker somatosensory cortex

Ramamurthy, D. L.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.

10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-08-11

3322 Secure and Federated Genome-Wide Association Studies for Biobank-Scale Datasets

Cho, H.; Froelicher, D.; Chen, J.; Edupalli, M.; Pyrgelis, A.; Troncoso-Pastoriza, J. R.; Hubaux, J.-P.; Berger, B.

10.1101/2022.11.30.518537 — bioinformatics — Posted on 2024-08-10

3323 Efficient clustering of large molecular libraries

Jung, V.; Lopez Perez, K.; Chen, L.; Huddleston, K.; Miranda Quintana, R. A.

10.1101/2024.08.10.607459 — bioinformatics — Posted on 2024-08-10

3324 Early differential impact of MeCP2 mutations on functional networks in Rett syndrome patient-derived human cerebral organoids

Osaki, T.; Delepine, C.; Osako, Y.; Kranz, D.; Levin, A. R.; Nelson, C.; Fagiolini, M.; Sur, M.

10.1101/2024.08.10.607464 — bioengineering — Posted on 2024-08-10

3325 The limitation of lipidation: conversion of semaglutide from once-weekly to once-monthly dosing

Schneider, E. L.; Hangasky, J. A.; Fernandez, R. d. V.; Ashley, G. W.; Santi, D. V.

10.1101/2024.08.10.607458 — bioengineering — Posted on 2024-08-10

3326 H3K36 Methylation - a Guardian of Epigenome Integrity

Shipman, G.; Padilla, R.; Horth, C.; Bareke, E.; Majewski, J.

10.1101/2024.08.10.607446 — genomics — Posted on 2024-08-10

3327 Development of a Novel Japanese Eel Myoblast Cell Line for Application in Cultured Meat Production

Ikeda, D.; Otsuka, Y.; Kan-no, N.

10.1101/2024.08.10.607424 — cell biology — Posted on 2024-08-10

3328 Therapeutic Spp1 silencing in TREM2+ cardiac macrophages suppresses atrial fibrillation

Momin, N.; Pabel, S.; Rudra, A.; Kumowski, N.; Lee, I.-H.; Mentkowski, K.; Yamazoe, M.; Stengel, L.; Muse, C. G.; Seung, H.; Paccalet, A.; Gonzalez-Correa, C.; Jacobs, E. B.; Grune, J.; Schloss, M. J.; Sossalla, S.; Wojtkiewicz, G.; Iwamoto, Y.; McMullen, P.; Mitchell, R. N.; Ellinor, P. T.; Anderson, D. G.; Naxerova, K.; Nahrendorf, M.; Hulsmans, M.

10.1101/2024.08.10.607461 — immunology — Posted on 2024-08-10

3329 Neural Mechanism Underlying Successful Classification of Amnestic Mild Cognitive Impairment Using Multi-Sensory-Evoked Potentials

Zhang, L.; Binns, M.; Chow, R.; Rabi, R.; Anderson, N. D. A.; Lu, J.; Freedman, M.; Alain, C.

10.1101/2024.08.10.607449 — neuroscience — Posted on 2024-08-10

3330 Slow but flexible or fast but rigid? Discrete and continuous processes compared

Priorelli, M.; Stoianov, I. P.

10.1101/2023.08.20.554008 — neuroscience — Posted on 2024-08-10

3331 A multiscale model of immune surveillance in micrometastases: towards cancer patient digital twins

L. Rocha, H.; Aguilar, B.; Getz, M.; Shmulevich, I.; Macklin, P.

10.1101/2023.10.17.562733 — systems biology — Posted on 2024-08-10

3332 Emergence of power-law distributions in protein-protein interaction networks through study bias

Blumenthal, D. B.; Lucchetta, M.; Kleist, L.; Fekete, S. P.; List, M.; Schaefer, M. H.

10.1101/2023.03.17.533165 — systems biology — Posted on 2024-08-10

3333 {Computer Modeling of Bevacizumab Drug Distribution after Intravitreal Injection in Rabbit and Human Eyes}

Chowdhury, J. M.; Chacin Ruiz, E. A.; Ohr, M. P.; Swindle-Reilly, K. E.; Ford Versypt, A. N.

10.1101/2023.05.05.539491 — systems biology — Posted on 2024-08-10

3334 A Multiomic Analysis Reveals How Breast Cancers Disseminated to the Bone Marrow Acquire Aggressive Phenotypes through Tumor-Stroma Tunnels

Sinha, S.; Callow, B.; Farfel, A.; Roy, S.; Chen, S.; Rajendran, S.; Buschhaus, J.; Luker, K. E.; Ghosh, P.; Luker, G. D.

10.1101/2023.03.18.533175 — cancer biology — Posted on 2024-08-10

3335 MyVivarium: A cloud-based lab animal colony management application with near-realtime ambient sensing

Vidva, R.; Raza, M. A.; Prabhakaran, J.; Sheikh, A.; Sharp, A.; Ott, H.; Moore, A.; Fleisher, C.; Pitychoutis, P. M.; Nguyen, T. V.; Sathyanesan, A.

10.1101/2024.08.10.607395 — bioinformatics — Posted on 2024-08-10

3336 Codon Usage Bias Analysis of Human Papillomavirus 18s L1 Protein and its Host Adaptability

Shinde, V. V.; Bankariya, S.; Kaur, P.

10.1101/2024.08.10.607454 — bioinformatics — Posted on 2024-08-10

3337 Weber's law and natural inference

Beck, J.; Kanitscheider, I.; Dehaene, G.; Pouget, A.

10.1101/2024.08.10.607448 — animal behavior and cognition — Posted on 2024-08-10

3338 Co-localized SNPs Affecting the Expression of Taste Perception Genes are linked to Alzheimer's Disease

Joseph, P. V.; Abbas, M.; Goodney, G.; Diallo, A.; Gaye, A.

10.1101/2024.08.10.607452 — genomics — Posted on 2024-08-10

3339 Optimized methods for mapping DNA double-strand-break ends and resection tracts and application to meiotic recombination in mouse spermatocytes

Kim, S.; Yamada, S.; Maekawa, K.; Keeney, S.

10.1101/2024.08.10.606181 — genomics — Posted on 2024-08-10

3340 Long-read transcriptomic identification of synaptic adaptation to amyloid pathology in the App(NL-G-F) knock-in mouse model of the earliest phase of Alzheimer's disease

Yaman, U.; Banks, G.; Gustavsson, E. K.; Mumford, P.; Magusali, N.; Taso, O. S.; Macpherson, H.; Carmona, S.; Murray, M.; Bains, R. S.; Forrest, H.; Stewart, M.; Scott, C.; Lipina, T. V.; Cheng, Z.; Tierney, A. L.; Unwin, R. D.; Botia, J. A.; Sala Frigerio, C.; Wells, S. E.; Hardy, J.; Soreq, L.; Wiseman, F. K.; Salih, D. A.

10.1101/2024.08.10.607237 — genetics — Posted on 2024-08-10

3341 Self-organizing ovarian somatic organoids preserve cellular heterogeneity and reveal cellular contributions to ovarian aging

Dipali, S. S.; Gowett, M. Q.; Kamat, P.; Converse, A.; Zaniker, E. J.; Fennell, A.; Chou, T.; Pritchard, M. T.; Zelinski, M.; Phillip, J. M.; Duncan, F. E.

10.1101/2024.08.10.607456 — cell biology — Posted on 2024-08-10

3342 Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection

Moore, K. M.; Foster, S. L.; Elrod, E. J.; Floyd, K. A.; Williams, M. E.; Kar, M.; Vander Velden, J.; Ellis, M.; Malik, A.; Wali, B.; Lapp, S.; Metz, A.; Bosinger, S. E.; Seder, R. A.; Amara, R. R.; Menachery, V. D.; Kohlmeier, J. E.; Grakoui, A.; Suthar, M. S.

10.1101/2024.08.08.607190 — immunology — Posted on 2024-08-10

3343 Quantitative comparison of the structural differences between NRAS and its mutations by well-tempered metadynamics simulations

Hu, Z.; Marti, J.

10.1101/2024.08.09.607354 — biophysics — Posted on 2024-08-10

3344 A pan-variant miniprotein inhibitor protects against SARS-CoV-2 variants

Lee, J.; Case, J. B.; Ravichandran, R.; Asarnow, D.; Tortorici, M. A.; Brown, J. T.; Sanapala, S.; Carter, L.; Baker, D.; Diamond, M. S.; Veesler, D.

10.1101/2024.08.08.606885 — biochemistry — Posted on 2024-08-10

3345 Single cell RNA sequencing reveals a shift in cell function and maturation of endogenous and infiltrating cell types in response to acute intervertebral disc injury

Clayton, S. W.; Sebastian, A.; Wilson, S. P.; Hum, N. R.; Walk, R. E.; Easson, G. W.; Vaidya, R. S.; Broz, K. S.; Loots, G. G.; Tang, S. Y.

10.1101/2024.08.10.607363 — cell biology — Posted on 2024-08-10

3346 Predict metal-binding proteins and structuresthrough integration of evolutionary-scale andphysics-based modeling

Dai, X.; Henderson, M.; Yoo, S.; Liu, Q.

10.1101/2024.08.09.607368 — bioinformatics — Posted on 2024-08-10

3347 A Refined Analysis of Neanderthal-Introgressed Sequences in Modern Humans with a Complete Reference Genome

Liang, S.-A.; Ren, T.; Zhang, J.; He, J.; Wang, X.; Jiang, X.; He, Y.; McCoy, R. C.; Fu, Q.; Akey, J. M.; Mao, Y.; Chen, L.

10.1101/2024.08.09.607285 — evolutionary biology — Posted on 2024-08-10

3348 YAP charge patterning mediates signal integration through transcriptional co-condensates

Meyer, K.; Yserentant, K.; Cheloor-Kovilakam, R.; Ruff, K. M.; Chung, C.-I.; Shu, X.; Huang, B.; Weiner, O. D.

10.1101/2024.08.10.607443 — cell biology — Posted on 2024-08-10

3349 taxmyPHAGE: Automated taxonomy of dsDNA phage genomes at the genus and species

Millard, A. D.; Denise, R.; Lestido, M.; Thomas, M.; Webster, D.; Turner, D.; Sicheritz-Ponten, T.

10.1101/2024.08.09.606593 — microbiology — Posted on 2024-08-10

3350 Pleiotropic cellular responses underlying antibiotic tolerance in Campylobacter jejuni

Cho, E.; Kim, J.; Hur, J. I.; Ryu, S.; Jeon, B.

10.1101/2024.08.09.607412 — microbiology — Posted on 2024-08-10

3351 Physiological oxygen concentration during sympathetic primary neuron culture improves neuronal health and reduces HSV-1 reactivation

Dochnal, S. A.; Krakowiak, P. A.; Whitford, A. L.; Cliffe, A. R.

10.1101/2024.08.09.607366 — microbiology — Posted on 2024-08-10

3352 The inattentional rhythm in audition

Lui, T. K.-Y.; Boglietti, E.; Zoefel, B.

10.1101/2024.08.10.607439 — neuroscience — Posted on 2024-08-10

3353 Quantitative comparison of single-cell RNA sequencing versus single-molecule RNA imaging for quantifying transcriptional noise

Khetan, N.; Zuckerman, B.; Calia, G. P.; Chen, X.; Arceo, X. G.; Weinberger, L. S.

10.1101/2024.08.09.607289 — systems biology — Posted on 2024-08-10

3354 Rpt5 encodes a receptor-like protein that provides broad and effective net form net blotch (Pyrenophora teres f. teres) resistance in barley

Effertz, K.; Richards, J. K.; Clare, S. J.; del Castillo, M.; Sharma Poudel, R.; Li, M.; Zhang, J.; Moscou, M. J.; Friesen, T.; Brueggeman, R. S.

10.1101/2024.08.09.607401 — plant biology — Posted on 2024-08-10

3355 The SH Protein of Mumps Virus is a Druggable Pentameric Viroporin

Devantier, K.; Toft-Bertelsen, T. L.; Prestel, A.; Kjaer, V. M. S.; Sahin, C.; Giulini, M.; Louka, S.; Spiess, K.; Manandhar, A.; Qvortrup, K.; Ulven, T.; Bentzen, B. H.; Bonvin, A.; MacAulay, N.; Kragelund, B. B.; Rosenkilde, M. M.

10.1101/2024.08.09.607002 — biophysics — Posted on 2024-08-10

3356 Different folding mechanisms in prion proteins from mammals with different disease susceptibility observed at the single-molecule level

Anand, U.; Patra, S.; Sekar, R. V.; Garen, C. R.; Woodside, M. T.

10.1101/2024.08.09.607387 — biophysics — Posted on 2024-08-10

3357 Auditory Cellular Cooperativity Probed Via Spontaneous Otoacoustic Emissions

Bergevin, C.; Whiley, R.; Wit, H.; Manley, G.; van Dijk, P.

10.1101/2024.08.09.607375 — biophysics — Posted on 2024-08-10

3358 Bayesian Estimation of Allele-Specific Expression in the Presence of Phasing Uncertainty

Zou, X.; Gomez, Z. W.; Reddy, T. E.; Allen, A. S.; Majoros, W. H.

10.1101/2024.08.09.607371 — bioinformatics — Posted on 2024-08-10

3359 Comprehensive assembly of monoclonal and mixed antibody sequences

Jiang, W.; Xiong, Y.; Xiao, J.; Wang, J.; Jiang, Z.; Luo, L.; Yuan, Q.; Xia, N.; Yu, R.

10.1101/2024.08.09.607415 — bioinformatics — Posted on 2024-08-10

3360 Synthetic mucus biomaterials synergize with antibiofilm agents to combat Pseudomonas aeruginosa biofilms

Yang, S.; Stern, A.; Duncan, G.

10.1101/2024.08.09.607383 — bioengineering — Posted on 2024-08-10

3361 Local photo-crosslinking of native tissue matrix regulates cell function

Ahmed, D. W.; Tan, M. L.; Gabbard, J.; Liu, Y.; Hu, M. M.; Stevens, M.; Midekssa, F. S.; Han, L.; Zemans, R. L.; Baker, B.; Loebel, C.

10.1101/2024.08.10.607417 — bioengineering — Posted on 2024-08-10

3362 Probing intracellular determinants of PARP inhibitor selectivity and pharmacology with CeTEAM

Pires, M. J.; Lovric, A.; Fabbrizi, E.; Rotili, D.; Altun, M.; Valerie, N. C. K.

10.1101/2024.08.09.607390 — biochemistry — Posted on 2024-08-10

3363 The double-edged effect of environmental fluctuations on evolutionary rescue

Shibasaki, S.; Yamamichi, M.

10.1101/2024.08.09.607399 — evolutionary biology — Posted on 2024-08-10

3364 Genetic predisposition towards multicellularity in Chlamydomonas reinhardtii

Chen, I.-C. K.; Khatri, S.; Herron, M. D.; Rosenzweig, F.

10.1101/2024.08.09.607418 — evolutionary biology — Posted on 2024-08-10

3365 Human rod photoreceptor outer segments are supported by accessory inner segment structures

Lewis, T. R.; Klementieva, N. V.; Phan, S.; Castillo, C. M.; Kim, K.-Y.; Cao, L. Y.; Ellisman, M.; Arshavsky, V. Y.; Alekseev, O.

10.1101/2024.08.09.607370 — cell biology — Posted on 2024-08-10

3366 The eduWOSM: an advanced optical microscope for education

Carter, N. J.; Martin, D. S.; Molloy, J. E.; Cross, R. A.

10.1101/2024.08.10.607181 — cell biology — Posted on 2024-08-10

3367 G protein-Coupled Receptor Associated Sorting ProteinGASP1 mediated trafficking of the Glucagon Like Peptide-1Receptor contributes to the development of tolerance toincretin drugs

Gaur, A.; Keeshen, C. M.; King, M.; Dirks, N.; Flisher, M.; Cummings, B. P.; Huising, M. O.; Whistler, J.

10.1101/2024.08.09.607397 — cell biology — Posted on 2024-08-10

3368 Circadian and permanent pools of extracellular matrix co-exist in tendon tissue, but have distinct rates of turnover and differential responses to ageing

Hoyle, A.; Chang, J.; Cutiongco, M. F.; O'Cualain, R.; Warwood, S.; Knight, D.; Meng, Q.-J.; Kadler, K. E.; Swift, J.

10.1101/2024.08.09.607297 — molecular biology — Posted on 2024-08-10

3369 The Toxoplasma gondii homolog of ATPase inhibitory factor 1 is critical for mitochondrial cristae maintenance and stress response

Usey, M. M.; Ruberto, A. A.; Huet, D.

10.1101/2024.08.09.607411 — molecular biology — Posted on 2024-08-10

3370 Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB

DeAngelo, J. D.; Maron, M. I.; Roth, J. S.; Silverstein, A. M.; Gupta, V.; Stransky, S.; Azofeifa, J.; Sidoli, S.; Gamble, M. J.; Shechter, D.

10.1101/2024.08.09.607355 — molecular biology — Posted on 2024-08-10

3371 Comparative genomic analysis of a Colombian strain of Leptospira santarosai serogroup Autumnalis serovar Alice and inference of its virulence factors

VILLARREAL JULIO, R. G.; Ordonez, B.; YepesBlandon, J. A.

10.1101/2024.08.09.607408 — microbiology — Posted on 2024-08-10

3372 Overcoming toxicity: why boom-and-bust cycles are good for non-antagonistic microbes

Wang, M.; Vladimirsky, A.; Giometto, A.

10.1101/2024.08.09.607393 — microbiology — Posted on 2024-08-10

3373 Prediction of symptomatic and asymptomatic bacteriuria in spinal cord injury patients using machine learning

Hoque, M. M.; Noorian, P.; Espinoza-Vergara, G.; To, J.; Leo, D.; Chari, P.; Weber, G.; Pryor, J.; Duggin, I. G.; Lee, B. B.; Rice, S. A.; McDougald, D.

10.1101/2024.08.09.607254 — microbiology — Posted on 2024-08-10

3374 In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity

Hagan, N. B.; Inaku, C.; Kunder, N.; White, T.; Iraguha, T.; Meyer, A.; Pauken, K.; Schenkel, J. M.

10.1101/2024.08.10.607414 — immunology — Posted on 2024-08-10

3375 Dynamic roles of ILC3 in endometrial repair and regeneration

Cuff, A. O.; Woon, E. V.; Bainton, T.; Browne, B.; Kirkwood, P. M.; Collins, F.; Gibson, D. A.; Saunders, P.; Horne, A. W.; Johnson, M. R.; MacIntyre, D. A.; Male, V.

10.1101/2024.08.10.606309 — immunology — Posted on 2024-08-10

3376 Type I TARPs regulate Kv7.2 potassium channels andsusceptibility to seizures

Ventura Rodrigues, M. V.; Inacio, A. S.; Soldovieri, M. V.; Ribau, S.; Leal, T. M.; Baurberg, T.; Mosca, I.; Ambrosino, P.; Amado, L.; Beltrao, N.; Caldeira, G. L.; Ribeiro, L. F.; Li, K. W.; Groc, L.; Ferreira, J. S.; Taglialatela, M.; Carvalho, A. L.

10.1101/2024.08.09.607194 — neuroscience — Posted on 2024-08-10

3377 Correlation and Matching Representations of Binocular Disparity across the Human Visual Cortex

Wundari, B. G.; Fujita, I.; Ban, H.

10.1101/2024.08.10.607440 — neuroscience — Posted on 2024-08-10

3378 Spatial transcriptomic data reveals pure cell types via the mosaic hypothesis

Wang, Y.; Koch, C.; Sümbül, U.

10.1101/2024.08.09.607193 — neuroscience — Posted on 2024-08-10

3379 Lipidomic and Proteomic Insights from Extracellular Vesicles in Postmortem Dorsolateral Prefrontal Cortex Reveal Substance Use Disorder-Induced Brain Changes

Okeoma, C. M.; Naushad, W.; Okeoma, B. C.; Gartner, C.; Santos Ortega, Y.; Vary, C.; Carregari, V. C.; Larsen, M. R.; Grassi-Oliveira, R.; Walss-Bass, C.

10.1101/2024.08.09.607388 — neuroscience — Posted on 2024-08-10

3380 A qMRI approach for mapping microscopic water populations and tissue relaxivity in the in vivo human brain.

Filo, S.; Mezer, A. A.

10.1101/2024.08.09.606771 — neuroscience — Posted on 2024-08-10

3381 Upstream alternative polyadenylation in SCN5A produces a short transcript isoform encoding a mitochondria-localized NaV1.5 N-terminal fragment that influences cardiomyocyte respiration

Witmer, N. H.; McLendon, J. M.; Stein, C. S.; Yoon, J.-Y.; Berezhnaya, E.; Elrod, J. W.; London, B.; Boudreau, R. L.

10.1101/2024.08.09.607406 — physiology — Posted on 2024-08-10

3382 Systemic identification of functionally conserved lncRNA metabolic regulators in human and mouse livers

Jiang, C.; Li, Z.; Li, P.; Ma, Y.; Seok, S.; Podguski, S.; Moturi, S.; Yoneda, N.; Kawai, K.; Uehara, S.; Ohnishi, Y.; Suemizu, H.; Zhang, J.; Cao, H.

10.1101/2024.08.10.607444 — physiology — Posted on 2024-08-10

3383 Hematobiochemical Alterations and Lesion Characterization Caused by Fasciolosis in Cattle Slaughtered at Gondar ELFORA Abattoir, Ethiopia

Temesgen, A. B.; Mitiku, T.; Birhan, M.; Kebede, M. C.; Yesuf, M.; Yayeh, M.; Alemayehu, M. M.; Anagaw, B.; Geda, A. M.; Tumebo, A. W.; Shiferaw, K. A.; Wassie, Z. G.; Berie, G. K.; Mengistu, B. A.; Feleke, M. G.; Edenshaw, F.; Yitie, M. T.; Kasse, G. E.; Melkamu, E.

10.1101/2024.08.10.607441 — pathology — Posted on 2024-08-10

3384 Triple Negative Breast Cancer Cells Acquire Lymphocyte Proteins and Genomic DNA During Trogocytosis with T Cells

Sivakoses, A.; Marcarian, H. Q.; Arias, A. M.; Lam, A. R.; Ihedioha, O. C.; Santamaria, J. A.; Gurtner, G. C.; Bothwell, A. L. M.

10.1101/2024.08.09.607029 — cancer biology — Posted on 2024-08-10

3385 Molecular dynamics simulations illuminate the role of sequence context in the ELF3-PrD-based temperature sensing mechanism in plants

Lindsay, R. J.; Viegas, R. G.; LEITE, V. B. P.; Wigge, P. A.; Hanson, S. M.

10.1101/2024.08.09.607385 — biophysics — Posted on 2024-08-10

3386 Somatic mutation phasing and haplotype extension using linked-reads in multiple myeloma

Foltz, S. M.; Li, Y.; Yao, L.; Terekhanova, N. V.; Weerasinghe, A.; Gao, Q.; Dong, G.; Schindler, M.; Cao, S.; Sun, H.; Jayasinghe, R. G.; Fulton, R. S.; Fronick, C. C.; King, J.; Kohnen, D. R.; Fiala, M. A.; Chen, K.; DiPersio, J. F.; Vij, R.; Ding, L.

10.1101/2024.08.09.607342 — bioinformatics — Posted on 2024-08-10

3387 Novel Insights into Post-Myocardial Infarction Cardiac Remodeling through Algorithmic Detection of Cell-Type Composition Shifts

Gural, B.; Kirkland, L.; Hockett, A.; Sandroni, P.; Zhang, J.; Rosa-Garrido, M.; Swift, S. K.; Chapski, D.; Flinn, M. A.; O'Meara, C. C.; Vondriska, T. M.; Patterson, M.; Jensen, B. C.; Rau, C.

10.1101/2024.08.09.607400 — bioinformatics — Posted on 2024-08-10

3388 RGAST: Relational Graph Attention Network for Spatial Transcriptome Analysis

Gong, Y.; Yu, Z.

10.1101/2024.08.09.607420 — bioinformatics — Posted on 2024-08-10

3389 Discovering nuclear localization signal universe through a novel deep learning model with interpretable attention units

Li, Y.; Pan, X.; Shen, H.-B.

10.1101/2024.08.10.606103 — bioinformatics — Posted on 2024-08-10

3390 Unveiling Fine-scale Spatial Structures and Amplifying Gene Expression Signals in Ultra-Large ST slices with HERGAST

Gong, Y.; Yuan, X.; Jiao, Q.; Yu, Z.

10.1101/2024.08.09.607422 — bioinformatics — Posted on 2024-08-10

3391 AllerTrans: An Improved Protein Allergenicity Prediction Model Using Deep Learning

Sarlakifar, F.; Malek, H.; Allahyari Fard, N.; Khotanlou, Z.

10.1101/2024.08.09.607419 — bioinformatics — Posted on 2024-08-10

3392 Impacts of Cell Ranger versions on Chromium gene expression data

Abugessaisa, I.; Hasegawa, A.; Walker, S.; Katayama, S.; Kere, J.; Kasukawa, T.

10.1101/2024.08.10.607413 — bioinformatics — Posted on 2024-08-10

3393 Fine-tuning of conditional Transformers for the generation of functionally characterized enzymes

Nicolini, M.; Saitto, E.; Jimenez Franco, R. E.; Cavalleri, E.; Mesiti, M.; Galeano Alfonso, A. J.; Malchiodi, D.; Paccanaro, A.; Robinson, P. N.; Casiraghi, E.; Valentini, G.

10.1101/2024.08.10.607430 — bioinformatics — Posted on 2024-08-10

3394 4D bioprinting shape-morphing tissues in granular support hydrogels: Sculpting structure and guiding maturation

Pramanick, A.; Hayes, T.; McEvoy, E.; Pandit, A.; Daly, A.

10.1101/2024.08.09.606830 — bioengineering — Posted on 2024-08-10

3395 Tissue-specific modulation of CRISPR activity by miRNA-sensing guide RNAs

Rinaldi, C.; Garcia Guerra, A.; Sathyaprakash, C.; de Jong, O. G.; Lim, W.; Vader, P.; Bath, J.; Aoki, Y.; Turberfield, A.; Wood, M.; EL Andaloussi, S.

10.1101/2024.08.09.605335 — bioengineering — Posted on 2024-08-10

3396 Imaging-Guided Metabolic Radiosensitization of Pediatric Rhabdoid Tumors

Xia, W.; Goff, M.; Singh, N.; Huang, J.; Gillespie, D.; Need, E.; Jensen, R.; Pagel, M.; Maity, A.; Shi, S.; Goel, S.

10.1101/2024.08.09.607364 — bioengineering — Posted on 2024-08-10

3397 An asymmetric nautilus-like HflK/C assembly controls FtsH proteolysis of membrane proteins

Ghanbarpour, A.; Telusma, B.; Powell, B. M.; Zhang, J. J.; Bolstad, I.; Vargas, C.; Keller, S.; Baker, T. A.; Sauer, R. T.; Davis, J. H.

10.1101/2024.08.09.604662 — biochemistry — Posted on 2024-08-10

3398 Genesis and regulation of C-terminal cyclic imides from protein damage

Xu, W.; Zhao, Z.; Su, M.; Jain, A.; Lloyd, H. C.; Feng, E. Y.; Cox, N.; Woo, C. M.

10.1101/2024.08.09.606997 — biochemistry — Posted on 2024-08-10

3399 Genome-wide analysis of somatic non-coding mutation patterns and mitochondrial heteroplasmy in type B1 and B2 thymomas

Fujikura, K.; Correa, I.; Heck, S.; King, J.; McLean, E.; Bille, A.; Nonaka, D.

10.1101/2024.08.09.607250 — genomics — Posted on 2024-08-10

3400 Universal dynamics of cohesin-mediated loop extrusion

Sabate, T.; Lelandais, B.; Robert, M.-C.; Szalay, M.; Tinevez, J.-Y.; Bertrand, E.; Zimmer, C.

10.1101/2024.08.09.605990 — genetics — Posted on 2024-08-10

3401 Non-destructive DNA extraction from specimens and environmental samples using DESS preservation solution for DNA barcoding

Ogiso-Tanaka, E.; Ito, M. A.; Shimada, D.

10.1101/2024.08.09.607403 — genetics — Posted on 2024-08-10

3402 Human genetic ancestry, Mycobacterium tuberculosis diversity and tuberculosis disease severity in Dar es Salaam, Tanzania

Zwyer, M.; Xu, Z. M.; Ross, A.; Hella, J.; Sasamalo, M.; Rotival, M.; Hiza, H.; Rutaihwa, L. K.; Reither, K.; Fellay, J.; Portevin, D.; Quintana-Murci, L.; Gagneux, S.; Brites, D.

10.1101/2024.08.10.607244 — evolutionary biology — Posted on 2024-08-10

3403 Drosophila melanogaster pigmentation demonstrates adaptive phenotypic parallelism but genomic unpredictability over multiple timescales

Berardi, S.; Rhodes, J. A.; Berner, M. C.; Greenblum, S. I.; Bitter, M. C.; Behrman, E. L.; Betancourt, N. J.; Bergland, A. O.; Petrov, D. A.; Rajpurohit, S.; Schmidt, P.

10.1101/2024.08.09.607378 — evolutionary biology — Posted on 2024-08-10

3404 Reverse development in the ctenophore Mnemiopsis leidyi

Soto-Angel, J. J.; Burkhardt, P.

10.1101/2024.08.09.606968 — ecology — Posted on 2024-08-10

3405 Environment, plant genetics, and their interaction shape important aspects of sunflower rhizosphere microbial communities

Bueno de Mesquita, C. P.; Walsh, C. M.; Attia, Z.; Koehler, B. D.; Tarble, Z. J.; Van Tassel, D. L.; Kane, N. C.; Hulke, B. S.

10.1101/2024.08.09.607089 — ecology — Posted on 2024-08-10

3406 Deep skin fibroblast-mediated macrophage recruitment supports acute wound healing

Amuso, V.; Haas, M.; Cooper, P.; Chatterjee, R.; Hafiz, S.; Salameh, S.; Gohel, C.; Mazumder, M.; Josephson, V.; Khorsandi, K.; Horvath, A.; Rahnavard, A.; Shook, B.

10.1101/2024.08.09.607357 — cell biology — Posted on 2024-08-10

3407 Identification of Meibomian gland stem cell populations and mechanisms of aging

Zhu, X.; Xu, M.; Portal, C.; Lin, Y.; Ferdinand, A.; Peng, T.; Morrisey, E. E.; Dlugosz, A. A.; Castellano, J. M.; Lee, V.; Seykora, J. T.; Iomini, C.; Millar, S. E.

10.1101/2024.08.09.607015 — cell biology — Posted on 2024-08-10

3408 TUG protein acts through a disordered region to organize the early secretory pathway

Parchure, A.; Tejada, H.; Xi, Z.; Su, M.; Julca-Zevallos, O.; Alcazar-Roman, A. R.; Yan, Y.; Liu, X.; Toomre, D.; Bogan, J. S.

10.1101/2024.08.09.607373 — cell biology — Posted on 2024-08-10

3409 Role of U11/U12 minor spliceosome gene ZCRB1 in Ciliogenesis and WNT Signaling

Powell-Rodgers, G.; Ur Rehman Pirzada, M.; Richee, J.; Jungers, C. F.; Colijn, S.; Stratman, A. N.; Djuranovic, S.

10.1101/2024.08.09.607392 — cell biology — Posted on 2024-08-10

3410 Modular Cell Line for Scalable and Rapid In Vitro Evaluation of Chimeric Antigen Receptors

Dubovik, S.; Dormeshkin, D.; Migas, A.

10.1101/2024.08.10.604092 — cell biology — Posted on 2024-08-10

3411 Development of a Novel Japanese Eel Myoblast Cell Line for Application in Cultured Meat Production

Ikeda, D.; Otsuka, Y.; Kan-no, N.

10.1101/2024.08.10.607424 — cell biology — Posted on 2024-08-10

3412 Assessing Autophagy Flux in Glioblastoma Temozolomide Resistant Cells

Clark, C.; Barzegar-Behrooz, A.; Cordani, M.; Shojaei, S.; Ghavami, S.

10.1101/2024.08.09.607348 — molecular biology — Posted on 2024-08-10

3413 The genetic basis of predation resistance in Pseudomonas species associated with the bactivorous soil amoeba Dictyostelium discoideum.

Steele, M. I.; Peiser, J. M.; Dawson, S. P. M.; Queller, D. C.; Strassmann, J. E.

10.1101/2024.08.09.607352 — microbiology — Posted on 2024-08-10

3414 Infectious subgenomic amplicon strategies for Japanese encephalitis and West Nile viruses

Singh, P. P.; Le, N. P. K.; Karniychuk, U.

10.1101/2024.08.09.607374 — microbiology — Posted on 2024-08-10

3415 Description of the structural and functional genomic composition of L. santarosai serovar Alice

Villarreal-Julio, R. G.; Manjarrez Montes, V. I.; Ordonez Perez, B. E.; Yepes-Blandon, J. A.

10.1101/2024.08.10.607426 — microbiology — Posted on 2024-08-10

3416 Spatial localization of CD16a at the human NK cell ADCC lytic synapse

Ross, P.; Fatima, H.; Leaman, D. P.; Matthias, J.; Spencer, K.; Zwick, M. B.; Henderson, S. C.; Mace, E. M.; Murin, C. D.

10.1101/2024.08.09.605851 — immunology — Posted on 2024-08-10

3417 Sleep defined by arousal threshold reveals decreases in corticocortical functional correlations independently from the conventional sleep stages

Picchioni, D.; Yang, F. N.; de Zwart, J. A.; Mandelkow, H.; Ozbay, P. S.; Chen, G.; Taylor, P. A.; Lam, N.; Chappel-Farley, M. G.; Chang, C.; Liu, J.; van Gelderen, P.; Duyn, J. H.

10.1101/2024.08.09.607376 — neuroscience — Posted on 2024-08-10

3418 Chickpea NCR13 disulfide cross-linking variants exhibit profound differences in antifungal activity and modes of action

Godwin, J.; Djami-Tchatchou, A. T.; Velivelli, S. L. S.; Tetorya, M.; Kalunke, R.; Pokhrel, A.; Zhou, M.; Buchko, G. W.; Czymmek, K.; Shah, D.

10.1101/2024.08.09.607347 — plant biology — Posted on 2024-08-10

3419 microRNA-1 Regulates Metabolic Flexibility in Skeletal Muscle via Pyruvate Metabolism

Ismaeel, A.; Peck, B. D.; Montgomery, M. M.; Burke, B. I.; Goh, J.; Kang, G.; Franco, A. B.; Xia, Q.; Goljanek-Whysall, K.; McDonagh, B.; McLendon, J. M.; Koopmans, P. J.; Jacko, D.; Schaaf, K.; Bloch, W.; Gehlert, S.; Wen, Y.; Murach, K. A.; Peterson, C. A.; Boudreau, R. L.; Fisher-Wellman, K. H.; McCarthy, J. J.

10.1101/2024.08.09.607377 — physiology — Posted on 2024-08-10

3420 Celastrol binds to pyruvate kinase and imitates the metabolic reprogramming of ATP

Zhang, X.; Jiang, X.; Wu, X.; Yang, Y.; Wang, J.; Zheng, J.; Zhou, M.; Qian, C.

10.1101/2024.08.09.607407 — pharmacology and toxicology — Posted on 2024-08-10

3421 dia-PASEF Proteomics of Tumor and Stroma LMD Enriched from Archived HNSCC Samples

Panigrahi, A.; Hunt, A. L.; Assis, D.; Willetts, M.; Kallakury, B. V.; Davidson, B.; Conrads, T. P.; Goldman, R.

10.1101/2024.08.09.607341 — cancer biology — Posted on 2024-08-10

3422 TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma

Li, J.; Huang, K.; McBride, F.; Sadagopan, A.; Gallant, D. S.; Thakur, M.; Khanna, P.; Li, B.; Ge, M.; Weiss, C. N.; Achom, M.; Xu, Q.; Huang, K.; Ryback, B. A.; Gui, M.; bar-peled, l.; Viswanathan, S. R.

10.1101/2024.08.09.607311 — cancer biology — Posted on 2024-08-10

3423 Global chromatin reorganization and regulation of genes of specific evolutionary age in differentiation and cancer

Raynal, F.; Sengupta, K.; Plewczynski, D.; Aliaga, B.; Pancaldi, V.

10.1101/2023.10.30.564438 — cancer biology — Posted on 2024-08-10

3424 Heterogenous organization in condensates of multiple transcription factors in embryonic stem cells

Mizutani, A.; Tan, C.; Sugita, Y.; Takada, S.

10.1101/2024.06.14.599027 — biophysics — Posted on 2024-08-10

3425 Accelerated Missense Mutation Identification in Intrinsically Disordered Proteins using Deep Learning

Bhattacharya, A.; Seth, S.

10.1101/2024.07.07.602404 — biophysics — Posted on 2024-08-10

3426 Drug Repurposing using Consilience of Knowledge Graph Completion Methods

Tu, R.; Sinha, M.; Gonzalez-Cavazos, A. C.; Hu, E.; Dhuliawala, S. Z.; McCallum, A.; Su, A. I.

10.1101/2023.05.12.540594 — bioinformatics — Posted on 2024-08-10

3427 Path-based reasoning in biomedical knowledge graphs with BioPathNet

Hu, Y.; Oleshko, S.; Firmani, S.; Zhu, Z.; Cheng, H.; Ulmer, M.; Arnold, M.; Colome-Tatche, M.; Tang, J.; Xhonneux, S.; Marsico, A.

10.1101/2024.06.17.599219 — bioinformatics — Posted on 2024-08-10

3428 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models

10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-10

3429 Rapid turnover of centromeric DNA reveals signatures of genetic conflict in Drosophila

Courret, C.; Hemmer, L.; Wei, X.; Patel, P. D.; Santinello, B.; Fuda, N. J.; Geng, X.; Chang, C.-H.; Mellone, B.; Larracuente, A. M.

10.1101/2023.08.22.554357 — evolutionary biology — Posted on 2024-08-10

3430 Performance and Robustness of Parameter Estimation from Phylogenetic Trees Using Neural Networks

Qin, T.; van Benthem, K.; Valente, L.; Etienne, R.

10.1101/2024.08.02.606350 — evolutionary biology — Posted on 2024-08-10

3431 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep

Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.

10.1101/2023.07.21.550073 — ecology — Posted on 2024-08-10

3432 Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

Ragusa, D.; Suen, C. W.; Torregrosa Cortes, G.; Pastorino, F.; Johns, A.; Ciciro, Y.; Dijkhuis, L.; van den Brink, S.; Cilli, M.; Byrne, C.; Ionescu, G.-A.; Cerveira, J.; Kranc, K. R.; Hernandez-Hernandez, V.; Ponzoni, M.; Bigas, A.; Garcia-Ojalvo, J.; Martinez Arias, A.; Pina, C.

10.1101/2022.10.07.511362 — developmental biology — Posted on 2024-08-10

3433 Mechanism of RSL3-Induced Ferroptotic Cell Death in HT22 Cells: Contributing Role of Protein Disulfide Isomerase

Hou, M.-J.; Huang, X.; Zhu, B. T.

10.1101/2024.05.27.596002 — cell biology — Posted on 2024-08-10

3434 OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier

Marini, S.; Barquero, A.; Wadhwani, A. A.; Bian, J.; Ruiz, J.; Boucher, C.; Prosperi, M.

10.1101/2024.03.15.585215 — molecular biology — Posted on 2024-08-10

3435 MAPK13 controls structural remodeling and disease after epithelial injury

Wu, K.; Zhang, Y.; Mao, D.; Iberg, C. A.; Yin-Declue, H.; Sun, K.; Keeler, S. P.; Wikfors, H. A.; Young, D.; Yantis, J.; Austin, S. R.; Byers, D. E.; Brody, S. L.; Crouch, E. C.; Holtzman, M. J.

10.1101/2024.05.31.596863 — immunology — Posted on 2024-08-10

3436 MAC3A and MAC3B modulate FLM splicing to repress photoperiod-dependent floral transition

Huang, Y.-W.; Tseng, C.-Y.; Tu, Y.-T.; Hsieh, H.-Y.; Wang, Y.-S.; Chen, Y.-Z.; Ly, Y.-T.; Tu, S.-L.; Lee, C.-M.

10.1101/2024.03.26.586198 — plant biology — Posted on 2024-08-10

3437 Ectopic cambia in Japanese wisteria (Wisteria floribunda) vines are associated with the expression of conserved KNOX genes

Cunha Neto, I. L.; Snead, A. A.; Landis, J. B.; Specht, C. D.; Onyenedum, J. G.

10.1101/2024.08.07.606835 — plant biology — Posted on 2024-08-10

3438 Assessment of Antimicrobial Therapy in Eradicating Chlamydia muridarum in Research Mice: Immune Status and its Impact on Outcomes

Palillo, M. B.; Carrasco, S.; Mishkin, N.; Palillo, J. A.; Lynch, D. B.; Lawton, S. K.; Aydin, M.; Mourino, A.; Lipman, N.; Ricart Arbona, R.

10.1101/2024.06.28.600682 — pharmacology and toxicology — Posted on 2024-08-10

3439 Qing-Luo-Yin eases angiogenesis in adjuvant-induced arthritis rats by activating PPARγ

zuo, j.; Yang, Z.

10.1101/2024.08.01.606254 — pharmacology and toxicology — Posted on 2024-08-10

3440 Structural and biochemical analysis of ligand binding in yeast Niemann-Pick type C1-related protein

Nel, L.; Thaysen, K.; Jamecna, D.; Olesen, E.; Szomek, M.; Langer, J.; Frain, K. M.; Hoeglinger, D.; Wustner, D.; Pedersen, B. P.

10.1101/2024.06.10.598172 — biophysics — Posted on 2024-08-10

3441 Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting

Wu, Y.; Yan, Y.; Yang, Y.; Bian, S.; Rivetta, A.; Allen, K.; Sigworth, F. J.

10.1101/2023.06.02.543446 — biophysics — Posted on 2024-08-10

3442 A machine learning-based approach to identify reliable gold standards for protein complex composition prediction

Yang, P.; Lee, Y.; Szymanski, D.; Xie, J.

10.1101/2023.10.25.564023 — bioinformatics — Posted on 2024-08-10

3443 Spotiflow: accurate and efficient spot detection for fluorescence microscopy with deep stereographic flow regression

Dominguez Mantes, A.; Herrera, A.; Khven, I.; Schlaeppi, A.; Kyriacou, E.; Tsissios, G.; Skoufa, E.; Santangeli, L.; Buglakova, E.; Durmus, E. B.; Manley, S.; Kreshuk, A.; Arendt, D.; Aztekin, C.; Ligner, J.; La Manno, G.; Weigert, M.

10.1101/2024.02.01.578426 — bioinformatics — Posted on 2024-08-10

3444 Signature Informed Sampling for Transcriptomic Data

Janakarajan, N.; Graziani, M.; Martinez, M. R.

10.1101/2023.10.26.564263 — bioinformatics — Posted on 2024-08-10

3445 The crystal structure of Nictaba reveals its carbohydrate-binding properties and a new lectin dimerization mode

Bloch, Y.; Osterne, V. J.; Savvides, S. N.; Van Damme, E. J.

10.1101/2024.05.06.592670 — biochemistry — Posted on 2024-08-10

3446 Biochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8

Rai, A.; Janning, P.; Vetter, I. R.; Goody, R. S.

10.1101/2024.06.17.599268 — biochemistry — Posted on 2024-08-10

3447 Computational structural prediction and chemical inhibition of the human mitochondrial pyruvate carrier protein heterodimer complex

Hadfield, C. M.; Walker, J. K.; Arnatt, C.; McCommis, K. S.

10.1101/2024.05.16.594520 — biochemistry — Posted on 2024-08-10

3448 Mechanistic origin and preimplantation development of uniparental and polyploid blastomeres

Zhao, Y.; Fernandez-Montoro, A.; Peeters, G.; Jatsenko, T.; De Coster, T.; Angel-Velez, D.; Lefevre, T.; Voet, T.; Tsuiko, O.; Kurg, A.; Smits, K.; Van Soom, A.; Vermeesch, J. R.

10.1101/2024.07.30.605883 — genetics — Posted on 2024-08-10

3449 Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

Fay, E. J.; Isterabadi, K.; Rezanka, C. M.; Le, J.; Daugherty, M. D.

10.1101/2024.05.09.593370 — evolutionary biology — Posted on 2024-08-10

3450 Environmental factors and cultural drift influence song evolution in New World Sparrows

Provost, K. L.; Yang, J.; Carstens, B. C.

10.1101/2023.09.01.555954 — evolutionary biology — Posted on 2024-08-10

3451 A punctuated burst of massive genomic rearrangements and the origin of non-marine annelids

Vargas-Chavez, C.; Benitez-Alvarez, L.; Martinez-Redondo, G. I.; Alvarez-Gonzalez, L.; Salces-Ortiz, J.; Eleftheriadi, K.; Escudero, N.; Guiglielmoni, N.; Flot, J.-F.; Novo, M.; Ruiz-Herrera, A.; McLysaght, A.; Fernandez, R.

10.1101/2024.05.16.594344 — evolutionary biology — Posted on 2024-08-10

3452 Towards an automated protocol for wildlife density estimation using camera-traps

Zampetti, A.; Mirante, D.; Palencia, P.; Santini, L.

10.1101/2024.08.05.606345 — ecology — Posted on 2024-08-10

3453 A minimal mathematical model for polarity establishment and centralspindlin-independent cytokinesis

Maxian, O.; Longhini, K.; Glotzer, M.

10.1101/2024.08.07.607072 — cell biology — Posted on 2024-08-10

3454 RGG motif-containing Scd6/LSM14A proteins regulate the translation of specific mRNAs in response to hydroxyurea-induced genotoxic stress

Mohanan, G.; Roy, R.; Malka-Mahieu, H.; Lamba, S.; Fabbri, L.; Biswas, A.; Martineau, S.; Labbe, C.; Vagner, S.; Rajyaguru, P. I.

10.1101/2022.07.12.499753 — cell biology — Posted on 2024-08-10

3455 Differential effects of prolonged post-fixation on immunohistochemical and histochemical staining for postmortem human brains

Ma, W.; Frigon, E.-M.; Maranzano, J.; Zeighami, Y.; Dadar, M.

10.1101/2024.05.13.593904 — neuroscience — Posted on 2024-08-10

3456 Examining the relationship between psychosocial adversity and inhibitory control: an fMRI study of children growing up in extreme poverty

Surani, Z.; Turesky, T. K.; Sullivan, E.; Shama, T.; Haque, R.; Islam, N.; Kakon, S. H.; Yu, X.; Petri, W. A.; Nelson, C.; Gaab, N.

10.1101/2024.02.05.578942 — neuroscience — Posted on 2024-08-10

3457 A synthetic method to assay polycystin ion channel biophysics

Larmore, M.; Esarte Palomero, O.; Kamat, N.; DeCaen, P. G.

10.1101/2024.05.06.592666 — synthetic biology — Posted on 2024-08-10

3458 Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum

Ferreira, S. S.; Pandey, S.; Hemminger, J.; Bozdag, S.; Antunes, M. S.

10.1101/2024.05.29.596347 — plant biology — Posted on 2024-08-10

3459 Multi-omics phenotyping characterizes molecular divergence underlying different clinical scenarios of inflammatory bowel disease

Tien, N. T. N.; Choi, E. J.; Thu, N. Q.; Yu, S. J.; Nguyen, D. N.; Kim, D. H.; Long, N. P.; Lee, H. S.

10.1101/2024.05.13.593901 — systems biology — Posted on 2024-08-10

3460 Multimodal system for recording individual-level behaviors in songbird groups

Rüttimann, L.; Wang, Y.; Rychen, J.; Tomka, T.; Hörster, H.; Rocha, M. D.; Hahnloser, R. H.

10.1101/2022.09.23.509166 — animal behavior and cognition — Posted on 2024-08-10

3461 Causal inference for multiple risk factors and diseases from genomics data

Machnik, N.; Mahmoudi, M.; Borczyk, M.; Kraetschmer, I.; Bauer, M. J.; Robinson, M. R.

10.1101/2023.12.06.570392 — genetics — Posted on 2024-08-10

3462 Regional patterns of human cortex development correlate with underlying neurobiology

Lotter, L. D.; Saberi, A.; Hansen, J. Y.; Misic, B.; Paquola, C.; Barker, G. J.; Bokde, A. L. W.; Desrivieres, S.; Flor, H.; Grigis, A.; Garavan, H.; Gowland, P.; Heinz, A.; Bruehl, R.; Martinot, J.-L.; Paillere, M.-L.; Artiges, E.; Papadopoulos Orfanos, D.; Paus, T.; Poustka, L.; Hohmann, S.; Froehner, J. H.; Smolka, M. N.; Vaidya, N.; Walter, H.; Whelan, R.; Schumann, G.; IMAGEN Consortium, ; Nees, F.; Banaschewski, T.; Eickhoff, S. B.; Dukart, J.

10.1101/2023.05.05.539537 — neuroscience — Posted on 2024-08-10

3463 Criterion placement threatens the construct validity of neural measures of consciousness

Fahrenfort, J. J.; Johnson, P. A.; Kloosterman, N. A.; Stein, T.; van Gaal, S.

10.1101/2024.02.22.581517 — neuroscience — Posted on 2024-08-10

3464 Oxidative stress response mediated by the yeast Rho5 GTPase depends on the proper spatiotemporal distribution of its dimeric GEF

Bischof, L.; Heinisch, J.

10.1101/2024.08.09.607359 — cell biology — Posted on 2024-08-09

3465 Optimising future rhino population management strategies using insights from genetic health assessments across India

Ghosh, T.; Kakati, P.; Sharma, A.; Mondol, S.

10.1101/2024.08.09.607316 — genetics — Posted on 2024-08-09

3466 The Phylogeny and the Evolution of Parasitic Strategies in Trematoda

Chuanyu, X.; Jakovlic, I.; Ye, T.; Song, R.; Zou, H.; Wang, G.; Li, W.; Zhang, D.

10.1101/2024.08.09.607286 — evolutionary biology — Posted on 2024-08-09

3467 Different ophthalmologic findings in induced models of Holoprosencephaly in zebrafish

Bulk, J.; Kyrychenko, V.; Heermann, S.

10.1101/2024.08.09.607329 — developmental biology — Posted on 2024-08-09

3468 Nanobody immunolabelling and three-dimensional imaging reveals spatially restricted LYVE1 expression by kidney lymphatic vessels in mice

Funk, E. M.; Jafree, D.; Hansmeier, N. R.; Abad Baucells, C.; Behncke, R. Y.; Pomeranz, G.; Kolatsi-Joannou, M.; Mason, W.; Moulding, D.; Russell, L. G.; Ulferts, S.; Wilson, L.; Long, D.; Haegerling, R.

10.1101/2024.08.09.607309 — immunology — Posted on 2024-08-09

3469 Making the effect visible - OX40 targeting nanobodies for in vivo imaging of activated T cells

Frecot, D. I.; Blaess, S.; Wagner, T. R.; Kaiser, P. D.; Traenkle, B.; Fandrich, M.; Jakobi, M.; Scholz, A. M.; Nueske, S.; Schneiderhan-Marra, N.; Gouttefangeas, C.; Kneilling, M.; Pichler, B. J.; Sonanini, D.; Rothbauer, U.

10.1101/2024.08.09.607337 — immunology — Posted on 2024-08-09

3470 Overexpression of the Apoe gene in the frontal cortex of mice causes sex-dependent changes in learning, attention, and anxiety-like behavior

Ramos, L.; Harr, A. E.; Zakas, F. L.; Essig, S. R.; Kempskie, G. J.; Fadil, N. A.; Schmid, M. G.; Pompy, M. D.; Curley, M. C.; Gabel, L. A.; Hallock, H. L.

10.1101/2024.08.08.607225 — neuroscience — Posted on 2024-08-09

3471 Do transformers and CNNs learn different concepts of brain age?

Siegel, N. T.; Kainmueller, D.; Deniz, F.; Ritter, K.; Schulz, M.-A.

10.1101/2024.08.09.607321 — neuroscience — Posted on 2024-08-09

3472 Spatio-temporal modeling of host-pathogen interactions using level set method

Permanes, S. R. E.; Mammeri, Y.; Leclerc, M.

10.1101/2024.08.09.607313 — plant biology — Posted on 2024-08-09

3473 Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis

Ruiz, A.; Benucci, S.; Meier, H.; Schultz, G.; Buczak, K.; Handschin, C.; Pena, R. C. G.; Treves, S.; Zorzato, F.

10.1101/2024.08.09.607317 — physiology — Posted on 2024-08-09

3474 Optimized LC-MS/MS method for Doxorubicin quantification: validating drug uptake and tumor reduction in zebrafish xenograft model of breast cancer

Rahman, G.; Pramanik, A.; Das, S.; Roy, A.; Bhargava, A.

10.1101/2024.08.09.607268 — cancer biology — Posted on 2024-08-09

3475 Interactions between neutrophils and macrophages harboring gram-negative bacteria promote obesity-associated breast cancer

Takle, S. T.; Grondal, S. M.; Lien, M. E.; Lianto, P.; Deng, W.; Lillestol, R. K.; Lonning, P.; Lorens, J. B.; Knappskog, S.; Halberg, N.

10.1101/2024.08.08.607253 — cancer biology — Posted on 2024-08-09

3476 EVE is an open modular data analysis software for event-based localization microscopy

Weber, L. M.; Martens, K. J. A.; Cabriel, C.; Gates, J. J.; Albecq, M.; Vermeulen, F.; Hein, K.; Izeddin, I.; Endesfelder, U.

10.1101/2024.08.09.607224 — biophysics — Posted on 2024-08-09

3477 Intra-cluster receptor density (IRD) dictates TNFR1 clusters' signaling efficacy

Jana, S.; Roy, P.; Das, J.; Biswas, P.; Nanda, N.; Sinha, B.; Sinha, D.

10.1101/2024.08.09.607302 — biophysics — Posted on 2024-08-09

3478 noSpliceVelo infers gene expression dynamics without separating unspliced and spliced transcripts

Mahajan, T.; Maslov, S.

10.1101/2024.08.08.607261 — bioinformatics — Posted on 2024-08-09

3479 SatXplor - A comprehensive pipeline for satellite DNA analyses in complex genome assemblies

Volaric, M.; Mestrovic, N.; Despot-Slade, E.

10.1101/2024.08.09.607335 — bioinformatics — Posted on 2024-08-09

3480 Beyond Differential Expression: Embracing Cell-to-Cell Variability in Single-Cell Gene Expression Data Analysis

Gatlin, V.; Gupta, S.; Romero, S.; Chapkin, R.; Cai, J. J.

10.1101/2024.08.08.607086 — bioinformatics — Posted on 2024-08-09

3481 In-silico identification of archaeal DNA-binding proteins

Donvil, L.; Housmans, J. A. J.; Peeters, E.; Vranken, W. F.; Orlando, G.

10.1101/2024.08.09.607351 — bioinformatics — Posted on 2024-08-09

3482 VieMedKG: Knowledge Graph and Benchmark for Traditional Vietnamese Medicine

Trinh, T.; Hoang, A.; Nhung, H. T. H.; Hy, T. S.

10.1101/2024.08.07.606195 — bioinformatics — Posted on 2024-08-09

3483 The Rad52 superfamily as seen by AlphaFold

Al-Fatlawi, A.; Hossen, M. B.; de Paula Lopes, S.; Stewart, A. F.; Schroeder, M.

10.1101/2024.08.09.607149 — bioinformatics — Posted on 2024-08-09

3484 Improved Spectral Inversion of Blood Oxygenation due to Reduced Tissue Scattering: Towards NIR-II Photoacoustic Imaging

Vincely, V. D.; Bayer, C. L.

10.1101/2024.08.08.607178 — bioengineering — Posted on 2024-08-09

3485 Hyoid bone position and upper airway patency: A computational finite element modeling study

Salman, D.; Amatoury, J.

10.1101/2024.08.09.607294 — bioengineering — Posted on 2024-08-09

3486 Multi-modal, Label-free, Optical Mapping of Cellular Metabolic Function and Oxidative Stress in 3D Engineered Brain Tissue Models

10.1101/2024.08.08.607216 — bioengineering — Posted on 2024-08-09

3487 Sexual Dimorphism in Jump Kinematics and Choreography in Peacock Spiders

Narendra, A.; Seibel, A.; Ramirez-Esquivel, F.; Joshi, P.; McLean, D. J.; Robledo-Ospina, L.; Rao, D.

10.1101/2024.08.09.607331 — animal behavior and cognition — Posted on 2024-08-09

3488 Phosphate transporter (Pht) gene families in rye (Secale cereale L.) - genome-wide identification and sequence diversity assessment

Chan-Rodriguez, D.; Koboyi, B. W.; Werghi, S.; Till, B. J.; Maksymiuk, J.; Shoormij, F.; Hilderlith, A.; Hawliczek, A.; Krolik, M.; Bolibok-Bragoszewska, H.

10.1101/2024.08.09.607312 — genomics — Posted on 2024-08-09

3489 Integrating gene expression and imaging data across Visium capture areas with visiumStitched

Eagles, N. J.; Bach, S. V.; Tippani, M.; Ravichandran, P.; Du, Y.; Miller, R. A.; Hyde, T.; Page, S. C.; Martinowich, K.; Collado-Torres, L.

10.1101/2024.08.08.607222 — genomics — Posted on 2024-08-09

3490 Whole genome sequence improvement with pedigree information and reference genotypic profiles, demonstrated in outcrossing apple

Vanderzande, S.; Peace, C.; van de Weg, E.

10.1101/2024.08.08.607141 — genetics — Posted on 2024-08-09

3491 Beyond neutral loci: Examining immune gene variation in tigers (Panthera tigris)

Aditi, B.; Ramakrishnan, U.

10.1101/2024.08.09.607326 — evolutionary biology — Posted on 2024-08-09

3492 Response diversity increases functional stability but decreases diversity and compositional stability of grassland communities

Zieschank, V.; Junker, R. R.

10.1101/2024.08.08.607162 — ecology — Posted on 2024-08-09

3493 A survey of duckweed species in southern Italy provided first occurrences of the hybrid Lemna x mediterranea in the wild

Romano, L. E.; Braglia, L.; Iannelli, M. A.; Lee, Y.; Morello, L.

10.1101/2024.08.09.607168 — ecology — Posted on 2024-08-09

3494 Rapid GIT transit time in volant vertebrates, with implications for convergence in microbiome composition

Cornelius Ruhs, E.; McFerrin, K.; Jones, D. N.; Cortes-Delgado, N.; Ravelomanantsoa, N. A. F.; Yeoman, C. J.; Plowright, R. K.; Brook, C. E.

10.1101/2024.08.09.607319 — ecology — Posted on 2024-08-09

3495 Divergence of discrete- versus continuous-time calculations of the temperature dependence of maximum population growth rate in a disease vector

Huxley, P. J.; Johnson, L. R.; Cator, L.; Pawar, S.

10.1101/2024.08.09.607340 — ecology — Posted on 2024-08-09

3496 Niche and spatial partitioning restrain ecological equivalence among microbes along aquatic redox gradient

Kajan, K.; Kirkegaard, R.; Pjevac, P.; Orlic, S.; Mehrshad, M.

10.1101/2024.08.09.607300 — ecology — Posted on 2024-08-09

3497 Hippo-TOR Signaling Crosstalks Underpin Microtubule Acetylation-linked Carcinogenesis in Drosophila Squamous Epithelia

Bhattacharya, R.; SINHA, P.; Mohan, N.

10.1101/2024.08.08.607173 — developmental biology — Posted on 2024-08-09

3498 Dynamic Wt1 expression in the gastrulation-stage mouse embryo specifies vascular and visceral smooth muscle cell fate independently from mesothelial fate.

Alsukari, S. H.; Ng, H. T.; Lang, L.; Lunn, S.; Beglinger, S.; Carr, L.; Boyes, M.; Turner, D. A.; Wilm, B.

10.1101/2024.08.08.607207 — developmental biology — Posted on 2024-08-09

3499 Holoprosencephaly and Cyclopia in bmp7b and bmpr1ba Crispant zebrafish

Kyrychenko, V.; Rensinghoff, P.; Bulk, J.; Frey, C.; Heermann, S.

10.1101/2024.08.09.607306 — developmental biology — Posted on 2024-08-09

3500 Hypoxia promotes airway differentiation in the human lung epithelium

Dong, Z.; Wit, N.; Agarwal, A.; Dubal, D.; van den Ameele, J.; Reid, A. J.; Nathan, J. A.; Rawlins, E.

10.1101/2024.08.09.607336 — developmental biology — Posted on 2024-08-09

3501 Tritrichomonas muris sensitizes the intestinal epithelium to doxorubicin-induced apoptosis

Janto, N. V.; Gleizes, A. R.; Sun, S. J.; Ari, G.; Gracz, A. D.

10.1101/2024.08.08.607206 — cell biology — Posted on 2024-08-09

3502 JMJD3 mediated senescence is required to overcome stress induced hematopoietic defects.

Nakata, Y.; Ueda, T.; Sera, Y.; Kanai, A.; Ikeda, K.-i.; Yamasaki, N.; Nagamachi, A.; Kobatake, K.; Taguchi, M.; Sotomaru, Y.; Ichinohe, T.; Honda, Z.-i.; Manabe, I.; Suda, T.; Takubo, K.; Kaminuma, O.; Honda, H.

10.1101/2024.08.08.607138 — cell biology — Posted on 2024-08-09

3503 Uncoupling de novo pyrimidine biosynthesis from mitochondrial electron transport by ectopic expression of cytosolic DHODH

Curtabbi, A.; Sanz-Cortes, R.; Enriquez, J. A.

10.1101/2024.08.09.607333 — molecular biology — Posted on 2024-08-09

3504 Cryo-EM structure and evolutionary history of the conjugation surface exclusion protein TraT

Seddon, C.; David, S.; Wong, J. L. C.; Ishimoto, N.; Bradshaw, J.; He, S.; Low, W. W.; Frankel, G.; Beis, K.

10.1101/2024.08.09.607165 — microbiology — Posted on 2024-08-09

3505 Population shifts in begomoviruses associated with tomato yellow leaf curl disease in western Mediterranean countries

Granier, M.; Faize, M.; Passera, S.; Urbino, C.; Peterschmitt, M.

10.1101/2024.08.09.607290 — microbiology — Posted on 2024-08-09

3506 Aspergillus species in Iceland: species distribution and cyp51A mutation testing in a 7.5-year clinical isolate collection

Hilmarsdottir, I.; Alcanzo, E.; Gerrits van den Ende, B.; Houbraken, J.; Hagen, F.

10.1101/2024.08.08.607273 — microbiology — Posted on 2024-08-09

3507 Outcome of H5N1 clade 2.3.4.4b virus infection in calves and lactating cows

Halwe, N. J.; Cool, K.; Breithaupt, A.; Schoen, J.; Trujillo, J. D.; Nooruzzaman, M.; Kwon, T.; Ahrens, A. K.; Britzke, T.; McDowell, C. D.; Piesche, R.; Singh, G.; Pinho dos Reis, V.; Kafle, S.; Pohlmann, A.; Gaudreault, N. N.; Corleis, B.; Ferreyra, F. M.; Carossino, M.; Balasuriya, U. B. R.; Hensley, L.; Morozov, I.; Covaleda, L. M.; Diel, D.; Ulrich, L.; Hoffmann, D.; Beer, M.; Richt, J. A.

10.1101/2024.08.09.607272 — microbiology — Posted on 2024-08-09

3508 Genetically and Functionally Distinct Immunoglobulin Heavy Chain Locus Duplication in Bats

Pursell, T.; Reers, A.; Mikelov, A.; Kotagiri, P.; Ellison, J. A.; Hutson, C. L.; Boyd, S. D.; Frank, H. K.

10.1101/2024.08.09.606892 — immunology — Posted on 2024-08-09

3509 Efficacy of a new multivalent vaccine for the control of bovine respiratory disease (BRD) in commercial fattening units

Tapiolas, M.; Gibert, M.; Montbrau, C.; Taberner, E.; Sole, M.; Santo Tomas, H.; Puig, A.; March, R.

10.1101/2024.08.07.606972 — immunology — Posted on 2024-08-09

3510 Ultrastructure of immature synaptic inputs in the lateral superior olive of the rodent brainstem

Ma, S.; Watanabe, S.; Gillespie, D. C.

10.1101/2024.08.09.606139 — neuroscience — Posted on 2024-08-09

3511 Hierarchical Bayesian Augmented Hebbian Reweighting Model of Perceptual Learning

Lu, Z.-L.; Yang, S.; Dosher, B. A.

10.1101/2024.08.08.606902 — neuroscience — Posted on 2024-08-09

3512 Identifying patterns differing between high-dimensional datasets with generalized contrastive PCA

de Oliveira, E. F.; Garg, P.; Hjerling-Leffler, J.; Batista-Brito, R.; Sjulson, L.

10.1101/2024.08.08.607264 — neuroscience — Posted on 2024-08-09

3513 Confidence and insight into working memories are shaped by attention and recent performance

Chekroud, S. R.; Nobre, A. C.; Kolling, N.

10.1101/2024.08.09.607293 — neuroscience — Posted on 2024-08-09

3514 Delta opioid receptors engage multiple signaling cascades to differentially modulate prefrontal GABA release with input and target specificity

Alexander, R.; Bender, K.

10.1101/2024.08.08.607246 — neuroscience — Posted on 2024-08-09

3515 Bayes vs. Weber: how to break a law of psychophysics

Prat-Carrabin, A.; Gershman, S. J.

10.1101/2024.08.08.607196 — neuroscience — Posted on 2024-08-09

3516 Investigating orientation adaptation following naturalistic film viewing

A-Izzeddin, E. J.; Rideaux, R.; Mattingley, J. B.; Harrison, W. J.

10.1101/2024.08.07.607115 — neuroscience — Posted on 2024-08-09

3517 Geometric eigenmode brain fingerprinting and its longitudinal associations with adolescent mental health and wellbeing

Boyes, A.; Schwenn, P. E.; Shan, Z.; Korgaonkar, M. S.; Pang, J. C.; Prince, T.; Mills, L.; Kennedy, M. F.; Hermens, D. F.

10.1101/2024.08.08.607260 — neuroscience — Posted on 2024-08-09

3518 Seed-competent alpha-synuclein pathology in metachromatic leukodystrophy: the expanding spectrum of alpha-synucleinopathy in sphingolipidoses

Ghanem, S.; Hawksworth, J.; Thom, S.; Hartanto, A. E.; O'Neill, J.; Ponraj, J.; Mansour, S.; Attems, J.; Pyle, A.; Johnson, L.; Baines, J.; Taylor, R. W.; Outeiro, T. F.; El-Agnaf, O.; Erskine, D.

10.1101/2024.08.09.607301 — neuroscience — Posted on 2024-08-09

3519 Characterization of Postsynaptic Glutamate Transporter Functionality in the Zebrafish Retinal First Synapse Across Different Wavelengths

Garbelli, M.; Niklaus, S.; Neuhauss, S. C.

10.1101/2024.08.09.607292 — neuroscience — Posted on 2024-08-09

3520 Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair

Hure, J.-B.; Foucault, L.; Ghayad, L.-M.; Marie, C.; Vachoud, N.; Baudouin, L.; Azmani, R.; Ivjanin, N.; Arevalo-Nuevo, A.; Pigache, M.; Bouslama-Oueghlani, L.; Chemelle, J.-A.; Dronne, M.-A.; Terreux, R.; Hassan, B.; Gueyffier, F.; Raineteau, O.; Parras, C.

10.1101/2024.08.08.607135 — neuroscience — Posted on 2024-08-09

3521 Alterations of the skeletal muscle nuclear proteome after acute exercise reveals a post-transcriptional influence.

Martin, R. A.; Viggars, M. R.; Sanford, J. A.; Taylor, Z. W.; Hansen, J. R.; Clair, G. C.; Adkins, J. N.; Douglas, C. M.; Esser, K. A.

10.1101/2024.08.08.607176 — physiology — Posted on 2024-08-09

3522 Thermoneutral Housing has Limited Effects on Social Isolation-Induced Bone Loss in Male C57BL/6J Mice

Mountain, R.; Peters, R.; Langlais, A.; Stohn, J. P.; Lary, C.; Motyl, K. J.

10.1101/2024.08.09.607315 — physiology — Posted on 2024-08-09

3523 Caution when using network partners for target identification in drug discovery

Tan, D.; Chen, Y.; Ilboudo, Y.; Liang, K. Y. H.; Butler-Laporte, G.; Richards, J. B.

10.1101/2024.08.08.607024 — pharmacology and toxicology — Posted on 2024-08-09

3524 Reducing Offsite Modification using 2-mercaptoethanol for Proteome Analysis.

Suto, A.; Matsui, T.; Kodera, Y.

10.1101/2024.08.09.607156 — biochemistry — Posted on 2024-08-09

3525 Machine learning reveals signatures of promiscuous microbial amidases for micropollutant biotransformations

Marti, T. D.; Schweizer, D.; Yu, Y.; Schaerer, M. R.; Probst, S. I.; Robinson, S. L.

10.1101/2024.08.09.606993 — biochemistry — Posted on 2024-08-09

3526 CarpeDeam: A De Novo Metagenome Assemblerfor Heavily Damaged Ancient Datasets

Kraft, L.; Soeding, J.; Steinegger, M.; Jochheim, A.; Fernandez-Guerra, A.; Renaud, G.

10.1101/2024.08.09.607291 — genomics — Posted on 2024-08-09

3527 De novo genome sequence assembly of the RNAi-tractable endosymbiosis model system Paramecium bursaria 186b reveals factors shaping intron repertoire

Leonard, G.; Jenkins, B. H.; Savory, F. R.; Kilias, E. S.; Maguire, F.; Varma, V.; Milner, D. S.; Richards, T. A.

10.1101/2024.08.09.607295 — genomics — Posted on 2024-08-09

3528 The repertoire of short tandem repeats across the tree of life

Chantzi, N.; Georgakopoulos-Soares, I.

10.1101/2024.08.08.607201 — genomics — Posted on 2024-08-09

3529 Drosophila ring chromosomes interact with sisters and homologs to produceanaphase bridges in mitosis.

Lin, H.-C.; Golic, M. M.; Hill, H. J.; Lemons, K. F.; Vuong, T. T.; Smith, M.; Golic, F. T.; Golic, K. G.

10.1101/2024.08.08.607186 — genetics — Posted on 2024-08-09

3530 A newly evolved gene is essential for efficient sperm entry into eggs in Drosophila melanogaster

Guay, S. Y.; Patel, P. H.; Thomalla, J. M.; McDermott, K. L.; O'Toole, J. M.; Arnold, S. E.; Obrycki, S. J.; Wolfner, M. F.; Findlay, G. D.

10.1101/2024.08.08.607187 — genetics — Posted on 2024-08-09

3531 Footprints of human migration in the population structure of wild wine yeast

Pena, J. J.; Scopel, E. F.; Ward, A. K.; Bensasson, D.

10.1101/2024.08.08.607167 — evolutionary biology — Posted on 2024-08-09

3532 Complex genetic determination of male-fertility restoration in the gynodioecious snail Physa acuta

Skarlou, E.; Laugier, F.; Bethune, K.; Chenin, T.; Donnay, J.-M.; Froissard, C.; David, P.

10.1101/2024.08.08.607164 — evolutionary biology — Posted on 2024-08-09

3533 The Evolution of Extreme Genetic Variability in a Parasite-Resistance Complex in a Planktonic Crustacean

Naser-Khdour, S.; Scheuber, F.; Fields, P. D.; Ebert, D.

10.1101/2024.08.09.607325 — evolutionary biology — Posted on 2024-08-09

3534 Coevolution and temporal dynamics of species interactions shape species coexistence

Duchenne, F.; Dominguez-Garcia, V.; Molina, F.; Bartomeus, I.

10.1101/2024.08.08.607160 — ecology — Posted on 2024-08-09

3535 Tracing Endometriosis: Coupling deeply phenotyped, single-cell based Endometrial Differences and AI for disease pathology and prediction

Duempelmann, L.; Sheppard, S.; Duo, A.; Skrabalova, J.; McKinnon, B.; Andrieu, T.; Goehlsdorf, D.; Muzumdar, S.; Donato, C.; Lusby, R.; Solass, W.; Bosmuller, H.; Nestorov, P.; Mueller, M.

10.1101/2024.08.09.606959 — molecular biology — Posted on 2024-08-09

3536 Hydrocarbon Metabolism and Petroleum Seepage as Ecological and Evolutionary Drivers for Cycloclasticus

Arrington, E. C.; Tarn, J.; Kivenson, V.; Nunn, B. L.; Liu, R. M.; Paul, B. G.; Valentine, D. L.

10.1101/2024.08.08.607087 — microbiology — Posted on 2024-08-09

3537 Extraction-free colorimetric RT-LAMP for SARS-CoV-2 RNA detection from saliva

Yang, Y.; Liu, X.; Tie, S.; Li, X.; Yang, X.; Cao, J.

10.1101/2024.08.09.607279 — microbiology — Posted on 2024-08-09

3538 New tools to monitor Pseudomonas aeruginosa infection and biofilms in vivo in C. elegans.

Ezcurra, M.; Ragno, M.; Xue, F.; Blackburn, S. A.; Fasseas, M.; Maitra, S.; Tholozan, F.; Thompson, R.; Sellars, L.; Hall, R.; Saunter, C.; Weinkove, D.

10.1101/2024.08.09.607303 — microbiology — Posted on 2024-08-09

3539 SARS-COV-2 nucleocapsid protein hijacks multiple components of the host nuclear transport machinery for distinct functions

Harrison, A. R.; Wang, S. Z.; Wagstaff, K. M.

10.1101/2024.08.09.607288 — microbiology — Posted on 2024-08-09

3540 Sputnik virophage disrupts the transcriptional regulation of its host giant virus

Chen, J.; Ogata, H.; Hikida, H.

10.1101/2024.08.09.607287 — microbiology — Posted on 2024-08-09

3541 The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2

Suryawanshi, R. K.; Jaishankar, P.; Correy, G. J.; Rachman, M. M.; O'Leary, P. C.; Taha, T. Y.; Zapatero-Belinchon, F. J.; McCavitt-Malvido, M.; Doruk, Y. U.; Stevens, M. G. V.; Diolati, M. E.; Jogalekar, M. P.; Richards, A. L.; Montano, M.; Rosecrans, J.; Matthay, M.; Togo, T.; Gonciarz, R. L.; Gopalkrishnan, S.; Neitz, R. J.; Krogan, N. J.; Swaney, D. L.; Shoichet, B. K.; Ott, M.; Renslo, A. R.; Ashworth, A.; Fraser, J. S.

10.1101/2024.08.08.606661 — immunology — Posted on 2024-08-09

3542 A honey bee-associated virus remains infectious and quantifiable in postmortem hosts

Payne, A. N.; Prayugo, V.; Dolezal, A. G.

10.1101/2024.08.08.607215 — pathology — Posted on 2024-08-09

3543 Evidence for S331-G-S-L within the amyloid core of myocilin olfactomedin domain fibrils based on low-resolution 3D solid-state NMR spectra

Saccuzzo, E. G.; Robang, A. S.; Gao, Y.; Chen, B. J.; Lieberman, R. L.; Paravastu, A. K.

10.1101/2024.08.09.606901 — biochemistry — Posted on 2024-08-09

3544 DNA methylation status classifies pleural mesothelioma cells according to their immune profile: implication for precision epigenetic therapy

Lofiego, M. F.; Tufano, R.; Bello, E.; Solmonese, L.; Marzani, F.; Piazzini, F.; Celesti, F.; Caruso, F. P.; Noviello, T. M. R.; Mortarini, R.; Anichini, A.; Ceccarelli, M.; Calabro', L.; Maio, M.; Coral, S.; Di Giacomo, A. M.; Covre, A.

10.1101/2024.08.08.607174 — cancer biology — Posted on 2024-08-09

3545 Breast cancer cell-derived extracellular vesicles accelerate collagen fibrillogenesis and integrate into the matrix

Tam, N. W.; Dimova, R.; Cipitria, A.

10.1101/2024.08.08.607183 — biophysics — Posted on 2024-08-09

3546 DeepKin: Predicting relatedness from low-coverage genomes and paleogenomes with convolutional neural networks

Guler, M. N.; Yilmaz, A.; Katircioglu, B.; Kantar, S.; Unver, T. E.; Vural, K. B.; Altinisik, N. E.; Akbas, E.; Somel, M.

10.1101/2024.08.08.607159 — bioinformatics — Posted on 2024-08-09

3547 StrainR2 accurately deconvolutes strain-level abundances in synthetic microbial communities

Heber, K.; Tian, S.; Betancurt-Anzola, D.; Koo, H.; Bisanz, J. E.

10.1101/2024.08.08.607172 — bioinformatics — Posted on 2024-08-09

3548 Discrete Ollivier-Ricci Flow Finds Distinct Subpopulations of Patients Treated with PD-1 Inhibition

Bannon, J. J.; Cantor, C. R.; Mishra, B.

10.1101/2024.08.08.606714 — bioinformatics — Posted on 2024-08-09

3549 Spatiotemporally Programmed Release of Aptamer Tethered Dual Angiogenic Growth Factors

Rana, D.; Rouwkema, J.

10.1101/2024.08.08.607163 — bioengineering — Posted on 2024-08-09

3550 Examining Sex-Specific DNA Methylation and Variability Post In Vitro Fertilization

Lemaire, M.; Smith, K. W.; Wilson, S. L.

10.1101/2024.08.08.604307 — genomics — Posted on 2024-08-09

3551 The ameliorative effect of C-Kit pos hepatic endothelial Mertk deficiency on nonalcoholic steatohepatitis

Fu, S.-W.; Gao, Y.-X.; Li, H.-Y.; Ren, Y.-F.; Wu, J.-C.; Li, Z.-H.; Xu, M.

10.1101/2024.08.08.607275 — molecular biology — Posted on 2024-08-09

3552 Systemic metabolic changes in acute and chronic lymphocytic choriomeningitis virus infection

Bartman, C. R.; Hou, S.; Correa, F.; Shen, Y.; da Silva-Diz, V.; Aleksandrova, M.; Herranz, D.; Rabinowitz, J.; Intlekofer, A. M.

10.1101/2024.08.09.607318 — immunology — Posted on 2024-08-09

3553 ProCogGraph: A Graph-Based Mapping of Cognate Ligand Domain Interactions

Crown, M.; Bashton, M.

10.1101/2024.08.08.607191 — bioinformatics — Posted on 2024-08-09

3554 Iso-Seq enables discovery of novel isoform variants in human retina at single cell resolution

Wang, L.; Urrutia-Cabrera, D.; Hung, S. S.-C.; Hewitt, A. W.; Lukowski, S. W.; Foord, C.; Wang, P.-Y.; Tilgner, H.; Wong, R.

10.1101/2024.08.08.607267 — genomics — Posted on 2024-08-09

3555 Coralline companions: Exploring microbes in coral ecosystems

Bharti, D.; Ghosh, A.; Kumar, S.

10.1101/2024.08.08.607119 — ecology — Posted on 2024-08-09

3556 Biogenesis, engineering and function of membranes in the CO2-fixing pyrenoid

Hennacy, J. H.; Atkinson, N.; Kayser-Browne, A.; Ergun, S. L.; Franklin, E.; Wang, L.; Kafri, M.; Fauser, F.; Vilarrasa-Blasi, J.; Jinkerson, R. E.; McCormick, A. J.; Jonikas, M. C.

10.1101/2024.08.08.603944 — molecular biology — Posted on 2024-08-09

3557 Neurofibromin deficiency alters the patterning and prioritization of motor behaviors in a state-dependent manner

Suarez, G. O.; Kumar, D. S.; Brunner, H.; Emel, J. A.; Teel, J.; Knauss, A.; Botero, V.; Broyles, C. N.; Stahl, A.; Bidaye, S. S.; Tomchik, S. M.

10.1101/2024.08.08.607070 — neuroscience — Posted on 2024-08-09

3558 Aperiodic neural activity distinguishes between phasic and tonic REM sleep

Rosenblum, Y.; Bogdany, T.; Nadasy, L. B.; Kovacs, I.; Gombos, F.; Ujma, P.; Bodizs, R.; Adelhöfer, N.; Simor, P.; Dresler, M.

10.1101/2024.08.08.606670 — neuroscience — Posted on 2024-08-09

3559 The force-sensing GPCR LPHN2 is indispensable for normal auditory function

Yang, Z.; Wang, M.-W.; Zhou, S.-H.; Song, Z.-c.; Zhu, K.-K.; Wen, X.; Zhang, Q.-Y.; Guan, Y.; Gao, J.-R.; Wang, X.-H.; Wang, Y.-Q.; Liu, W.-W.; Xu, L.; Xiong, W.; Chai, R.; Wang, C.; Xu, Z.-G.; Yu, X.; Sun, J.-P.

10.1101/2023.10.24.563883 — physiology — Posted on 2024-08-09

3560 Dissecting the metabolic costs of up- and down-hill walking

Jessup, L. N.; Kelly, L. A.; Cresswell, A. G.; Lichtwark, G. A.

10.1101/2024.08.08.607266 — physiology — Posted on 2024-08-09

3561 A force-sensitive adhesion GPCR is indispensable in normal equilibrioception

Yang, Z.; Zhou, S.; Zhang, Q.; Song, Z.; Liu, W.; Sun, Y.; Wang, M.; Fu, X.; Zhu, K.; Guan, Y.; Qi, J.; Wang, X.; Sun, Y.; Lu, Y.; Ping, Y.; Xi, Y.; Xu, Z.; Xiong, W.; Qin, W.; Yang, W.; Yi, F.; Yu, X.; Chai, R.; Sun, J.

10.1101/2023.10.24.563886 — physiology — Posted on 2024-08-09

3562 Biomolecular condensates and biogeomorphological systems exhibit a phase-separation behavior unified by a mass-conserving model

Li, C.; Guo, M.-T.; He, X.; Liu, Q.-X.; Qi, Z.

10.1101/2024.08.08.607271 — biophysics — Posted on 2024-08-09

3563 Peptide-specific chemical language model successfully predicts membrane diffusion of cyclic peptides

Feller, A. L.; Wilke, C. O.

10.1101/2024.08.09.607221 — bioinformatics — Posted on 2024-08-09

3564 Computational Prediction of Multiple Antigen Epitopes

Viswanathan, R.; Carroll, M.; Roffe, A.; Fajardo, J. E.; Fiser, A.

10.1101/2024.08.08.607232 — bioinformatics — Posted on 2024-08-09

3565 Sequencing of historical plastid genomes reveal exceptional genetic diversity in early domesticated rye plants

Komluski, J.; Filatova, S.; Schlütz, F.; Claassen, B.; Roesch, M.; Krause-Kyora, B.; Kirleis, W.; Stukenbrock, E.

10.1101/2024.08.08.607158 — evolutionary biology — Posted on 2024-08-09

3566 A site selection decision framework for effective kelp restoration

Giraldo-Ospina, A.; Bell, T. W.; Carr, M.; Caselle, J.

10.1101/2024.08.08.607095 — ecology — Posted on 2024-08-09

3567 The Performance and Potential of Deep Learning for Predicting Species Distributions

Kellenberger, B. A.; Winner, K.; Jetz, W.

10.1101/2024.08.09.607358 — ecology — Posted on 2024-08-09

3568 Forecasting hotspots of grassland suitability under climate change for restoration

Rana, S. K.; Lindstrom, J.; Lehrer, M. A.; Ahlering, M.; Hamilton, J.

10.1101/2024.08.08.607270 — ecology — Posted on 2024-08-09

3569 A sperm-enriched 5'fragment of tRNA-Valine regulates preimplantation embryonic transcriptome and development

Liu, S.; Holmes, A. D.; Katzman, S.; Sharma, U.

10.1101/2024.08.08.607197 — developmental biology — Posted on 2024-08-09

3570 Centrocortin potentiates co-translational localization of its mRNA to the centrosome via dynein

Zein-Sabatto, H.; Brockett, J. S.; Jin, L.; Husbands, C.; Lee, J.; Fang, J.; Buehler, J.; Bullock, S. L.; Lerit, D. A.

10.1101/2024.08.09.607365 — cell biology — Posted on 2024-08-09

3571 Adaptive immunity to retroelements promotes barrier integrity

Wells, A. C.; Lima-Junior, D. S.; Link, V. M.; Smelkinson, M.; Krishnamurthy, S. R.; Chi, L.; Segrist, E.; Rivera, C. A.; Teijeiro, A.; Bouladoux, N.; Belkaid, Y.

10.1101/2024.08.09.606346 — immunology — Posted on 2024-08-09

3572 Brain-Engrafted Monocyte-derived Macrophages from Blood and Skull-Bone Marrow Exhibit Distinct Identities from Microglia

Du, S.; Drieu, A.; Cheng, Y.; Storck, S.; Rustenhoven, J.; Mamuladze, T.; Bhattarai, B.; Brioschi, S.; Nguyen, K.; Ou, F.; Cao, J.; Rodrigues, P.; Smirnov, I.; DeNardo, D.; Ginhoux, F.; Cella, M.; Colonna, M.; Kipnis, J.

10.1101/2024.08.08.606900 — immunology — Posted on 2024-08-09

3573 Enhancement of response learning in male rats with intrastriatal infusions of a BDNF -TrkB agonist, 7,8-dihydroxyflavone

Gardner, R. S.; Ambalavanar, M. T.; Gold, P. E.; Korol, D. L.

10.1101/2024.08.08.606692 — neuroscience — Posted on 2024-08-09

3574 Ion channels that mediate calcium-dependent control of spike patterns are spatially organized across the soma in relation to a cytoskeletal assembly

Sahu, G.; Greening, D.; Nicola, W.; Turner, R. W.

10.1101/2024.08.08.607230 — neuroscience — Posted on 2024-08-09

3575 Magnetoencephalography dimensionality reduction informed by dynamic brain states

Cathignol, A. E.; Kusch, L.; Angiolelli, M.; Troisi Lopez, E.; Polverino, A.; Romano, A.; Sorrentino, G.; Jirsa, V.; Rabuffo, G.; Sorrentino, P.

10.1101/2024.08.08.607151 — neuroscience — Posted on 2024-08-09

3576 Myo-inositol and total NAA in the hippocampus are linked to CSF tau pathology in cognitively normal older adults

Noche, J. A.; Vanderlip, C.; Wright, S. T.; Sordo, L.; Head, E.; Stark, C.

10.1101/2024.08.09.607353 — neuroscience — Posted on 2024-08-09

3577 Local Nearby Bifurcations Lead to Synergies in Critical Slowing Down: the Case of Mushroom Bifurcations

Fucho, M.; Maretvadakethop, S.; Perez-Carrasco, R.; Haro, A.; Alarcon, T.; Sardanyes, J. d. R.

10.1101/2024.08.08.607203 — systems biology — Posted on 2024-08-09

3578 A PthXo2B ortholog in Xanthomonas oryzae pv oryzae strain IX-221 acts as a major virulence factor on indica rice without activating a Clade III SWEET gene.

Mishra, P.; S, S.; Carpenter, S. C.; Sekar, H.; S, V.; N, A. K.; Dash, P. K.; Bogdanove, A. J.; Rai, R.

10.1101/2024.08.08.607113 — plant biology — Posted on 2024-08-09

3579 A genome-wide association study identifies markers and candidate genes affecting tolerance to the wheat pathogen Zymoseptoria tritici

Mikaberidze, A.; McDonald, B. A.; Kronenberg, L.

10.1101/2024.08.08.607179 — plant biology — Posted on 2024-08-09

3580 A cell fractionation and quantitative proteomics pipeline to enable functional analyses of cotton fiber development

Lee, Y.; Rani, H.; Mallery, E. L.; Szymanski, D. B.

10.1101/2024.08.08.603566 — plant biology — Posted on 2024-08-09

3581 Ophthalmic acid is a bloodborne metabolite that contributes to age-induced cardiomyocyte hypertrophy

Mehdipour, M.; Park, S.; Wei, W.; Long, J. Z.; Huang, G. N.

10.1101/2024.08.08.607218 — physiology — Posted on 2024-08-09

3582 DMT1 knockout abolishes ferroptosis induced mitochondrial dysfunction in C. elegans amyloid beta proteotoxicity

Peng, W.; Chung, K. B.; Lawrence, B. P.; O'Banion, M. K.; Dirksen, R. T.; Wojtovich, A. P.; Onukwufor, J. O.

10.1101/2024.08.08.607074 — pharmacology and toxicology — Posted on 2024-08-09

3583 Pyruvate from bone marrow mesenchymal stem cells supports myeloma redox homeostasis and anabolism

Vera-Siguenza, E.; Escribano-Gonzalez, C.; Serrano-Gonzalo, I.; Eskla, K.-L.; Speakman, C.; Huerta-Uribe, A.; Vettore, L.; Rana, H.; Boufersaoui, A.; Vellama, H.; Nashiebi, R.; Cloete, I.; Roberts, J.; Basu, S.; Drayson, M.; Bunce, C.; Pratt, G.; Spill, F.; Maddocks, O. D. K.; Tennant, D. A.

10.1101/2024.08.08.607157 — cancer biology — Posted on 2024-08-09

3584 Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity

Weissenrieder, J. S.; Peura, J.; Paudel, U.; Bhalerao, N.; Weinmann, N.; Johnson, C.; Wengyn, M.; Drager, R.; Furth, E. E.; Simin, K.; Ruscetti, M.; Stanger, B.; Rustgi, A. K.; Pitarresi, J. R.; Foskett, J. K.

10.1101/2024.08.08.607195 — cancer biology — Posted on 2024-08-09

3585 Efficient and effective identification of cancer neoantigens from tumor only RNA-seq

Tatoni, D.; Dalsass, M.; Brunelli, G.; Grandi, G.; Chiariello, M.; D'Aurizio, R.

10.1101/2024.08.08.607127 — bioinformatics — Posted on 2024-08-09

3586 PyBootNet: A Python Package for Bootstrapping and Network Construction

Akhavan, S. R.; Kelley, S. T.

10.1101/2024.08.08.607205 — bioinformatics — Posted on 2024-08-09

3587 An Augmented Reality Visor for Intraoperative Visualization, Guidance and Temperature Monitoring using Fluorescence

Cipolato, O.; Fauconneau, M.; LeValley, P. J.; Nissler, R.; Suter, B.; Herrmann, I. K.

10.1101/2024.08.08.607031 — bioengineering — Posted on 2024-08-09

3588 Organ Chips with integrated multifunctional sensors enable continuous metabolic monitoring at controlled oxygen levels

Izadifar, Z.; Charrez, B.; Almeida, M.; Robben, S.; Pilobello, K.; van der Graaf-Mas, J.; Benz, M.; Marquez, S. L.; Ferrante, T. C.; Shcherbina, K.; Gould, R.; LoGrande, N. T.; Sesay, A. M.; Ingber, D. E.

10.1101/2024.08.08.606660 — bioengineering — Posted on 2024-08-09

3589 The molecular structure of an axle-less F1-ATPase

Furlong, E. J.; Reininger-Chatzigiannakis, I.-B. P.; Zeng, Y. C.; Brown, S. H. J.; Sobti, M.; Stewart, A. G.

10.1101/2024.08.08.607276 — biochemistry — Posted on 2024-08-09

3590 The Neuroactive Potential of the Elderly Human Gut Microbiome is Associated with Mental Health Status

Calderon Romero, P. F.; Valderrama, B.; Bastiaanssen, T.; Lillo, P.; Thumala, D.; Clarke, G.; Cryan, J. F.; Slachevsky, A.; Gonzalez-Billault, C.; Court, F.

10.1101/2024.08.08.607034 — animal behavior and cognition — Posted on 2024-08-09

3591 Genomic re-sequencing reveals substantial mutational divergence across genetically engineered strains of model archaea

Soborowski, A. L.; Hackley, R. K.; Hwang, S.; Zhou, G.; Dulmage, K. A.; Schonheit, P.; Daniels, C.; Bisson, A.; Marchfelder, A.; Maupin-Furlow, J. A.; Allers, T.; Schmid, A. K.

10.1101/2024.08.08.607208 — genomics — Posted on 2024-08-09

3592 Epigenetic heterogeneity shapes the transcriptional landscape of regional microglia

Margetts, A. V.; Vilca, S. J.; Bourgain-Guglielmetti, F.; Tuesta, L. M.

10.1101/2024.08.08.607229 — genetics — Posted on 2024-08-09

3593 Msh2-Msh3 DNA-binding is not sufficient to promote trinucleotide repeat expansions in Saccharomyces cerevisiae

Casazza, K. M.; Williams, G. M.; Johengen, L.; Twoey, G.; Surtees, J. A.

10.1101/2024.08.08.607243 — genetics — Posted on 2024-08-09

3594 Recent climate change strongly impacted the population dynamic of a North American insect pest species

Boulanger, Y.; Desaint, A.; Martel, V.; Marchand, M.; Massoda Tonye, S.; Saint-Amant, R.; Regniere, J.

10.1101/2024.08.08.607030 — ecology — Posted on 2024-08-09

3595 Tunable Cytosolic Chloride Indicators for Real-Time Chloride Imaging in Live Cells

Morse, J.; Nadiveedhi, M. R.; Schmidt, M.; Tang, F.-K.; Hladun, C.; Ganesh, P.; Qiu, Z.; Leung, K.

10.1101/2024.08.08.606814 — cell biology — Posted on 2024-08-09

3596 SILAC-based quantification reveals modulation of the immunopeptidome in BRAF and MEK inhibitor sensitive and resistant tumor cells

Bernhardt, M.; Rech, A.; Berthold, M.; Lappe, M.; Herbel, J.-N.; Erhard, F.; Paschen, A.; Schilling, B.; Schlosser, A.

10.1101/2024.08.08.606999 — immunology — Posted on 2024-08-09

3597 Spatial Transcriptomic Analysis Reveals HDAC Inhibition Modulates Microglial Dynamics to Protect Against Ischemic Stroke in Mice

Jayaraj, K.; Kumar, R.; Shyamasundar, S.; Polepalli, J. S.; Arumugam, T.; Dheen, S. T.

10.1101/2024.08.08.607139 — neuroscience — Posted on 2024-08-09

3598 The neural correlates of social rejection in the cyberball paradigm: An arterial spin labelling study

Labek, K.; Viviani, R.

10.1101/2024.08.08.607136 — neuroscience — Posted on 2024-08-09

3599 Emergence of temporal noise hierarchy in co-regulated genes of multi-output feed-forward loop

Nandi, M.

10.1101/2024.08.08.607134 — systems biology — Posted on 2024-08-09

3600 A Draft Pacific Ancestry Pangenome Reference

Littlefield, C. C.; Lazaro-Guevara, J. M.; Stucki, D.; Lansford, M.; Pezzolesi, M. H.; Taylor, E. J.; Wolfgramm, E. M. C.; Taloa, J.; Lao, K.; Dumaguit, C. D.; Ridge, P. G.; Tavana, J. P.; Holland, W. L.; Raphael, K. L.; Pezzolesi, M. G.

10.1101/2024.08.07.606392 — genomics — Posted on 2024-08-09

3601 Multimodal AI/ML for discovering novel biomarkers and predicting disease using multi-omics profiles of patients with cardiovascular diseases

Degroat, W.; Abdelhalim, H.; Peker, E.; Sheth, N.; Narayanan, R.; Zeeshan, S.; Liang, B. T.; Ahmed, Z.

10.1101/2024.08.07.607041 — genomics — Posted on 2024-08-09

3602 The danger zone: the joint trap of incomplete lineage sorting and long-branch attraction in placing Rafflesiaceae

Cai, L.; Liu, L.; DAVIS, C. C.

10.1101/2024.08.07.606681 — evolutionary biology — Posted on 2024-08-09

3603 NKX2.2 and KLF4 cooperate to regulate alpha cell identity

Brooks, E. P.; Casey, M. R.; Wells, K. L.; Liu, T.-Y.; Van Orman, M.; Sussel, L.

10.1101/2024.08.07.607083 — developmental biology — Posted on 2024-08-09

3604 ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration

Hirano, S.; Kondo, Y.; Kinoshita, N.; Otani, T.; Furuse, M.; Ueno, N.; Aoki, K.

10.1101/2024.08.09.607278 — cell biology — Posted on 2024-08-09

3605 CD131 Contributes to Ulcerative Colitis Pathogenesis by Promoting Macrophage Infiltration

Wu, Z.; Liu, L.; He, C.; Xiao, L.; Yun, D.; Chen, J.; Liu, Z.; Li, W.; Lv, Q.; Tan, X.

10.1101/2024.08.07.606991 — immunology — Posted on 2024-08-09

3606 Fidelity of focal sound source reproduction by higher (9th) order ambisonics and perceptual effects of reproduction errors

Zargarnezhad, N.; Mesquita, B.; Macpherson, E. A.; Johnsrude, I.

10.1101/2024.08.07.606870 — neuroscience — Posted on 2024-08-09

3607 Disrupted stimulus encoding shapes tactile perception in autism.

Semelidou, O.; Gauvrit, T.; Vandromme, C.; Cornier, A.; Saint-Jean, A.; Le Feuvre, Y.; Ginger, M.; Frick, A.

10.1101/2024.08.08.607129 — neuroscience — Posted on 2024-08-09

3608 PTEN deletion in the adult dentate gyrus induces Epilepsy

Yonan, J. M.; Chen, K. D.; Baram, T. Z.; Steward, O.

10.1101/2024.08.07.606938 — neuroscience — Posted on 2024-08-09

3609 A principled approach to community detection in interareal cortical networks

Armas, J. S. M.; Knoblauch, K.; Kennedy, H.; Toroczkai, Z.

10.1101/2024.08.07.606907 — neuroscience — Posted on 2024-08-09

3610 Neuropathology in an α-synuclein preformed fibril mouse model occurs independent of the Parkinson's disease-linked lysosomal ATP13A2 protein

Massari, C. M.; Dues, D. J.; Bergsma, A.; Sipple, K.; Moore, D. J.

10.1101/2024.08.07.607077 — neuroscience — Posted on 2024-08-09

3611 Wink or blush? Pupil-linked brain arousal signals both change and uncertainty during assessment of changing environmental regularities

Pajkossy, P.; Gesztesi, G.

10.1101/2024.08.07.607112 — neuroscience — Posted on 2024-08-09

3612 LimbNET: collaborative platform for simulating spatial patterns of gene networks in limb development

Matyjaszkiewicz, A.; Sharpe, J.

10.1101/2024.08.07.607075 — systems biology — Posted on 2024-08-09

3613 Engineering the plant intracellular immune receptor Sr50 to restore recognition of the AvrSr50 escape mutant

Seong, K.; Wei, W.; Vega, B.; Dee, A.; Ramirez-Bernardino, G.; Kumar, R.; Parra, L.; Krasileva, K.

10.1101/2024.08.07.607039 — plant biology — Posted on 2024-08-09

3614 Ectopic cambia in Japanese wisteria (Wisteria floribunda) vines are associated with the expression of conserved KNOX genes

Cunha Neto, I. L.; Snead, A. A.; Landis, J. B.; Specht, C. D.; Onyenedum, J. G.

10.1101/2024.08.07.606835 — plant biology — Posted on 2024-08-09

3615 Dihydroxyhexanoic acid biosynthesis controls turgor in pathogenic fungi

Kumakura, N.; Motoyama, T.; Miyazawa, K.; Nogawa, T.; Yonehara, K.; Sakai, K.; Ishihama, N.; Matsumori, K.; Gan, P.; Koshino, H.; Fukuma, T.; O'Connell, R. J.; Shirasu, K.

10.1101/2024.08.07.606736 — plant biology — Posted on 2024-08-09

3616 Tumor localization strategies of multi-cancer early detection tests: a quantitative assessment

Tyson, C.; Li, K. H.; Cao, X.; O'Brien, J. M.; Fishman, E. K.; O'Donnell, E. K.; Duran, C.; Parthasarathy, V.; Rego, S. P.; Choudhry, O. A.; Beer, T. M.

10.1101/2024.08.07.607020 — cancer biology — Posted on 2024-08-09

3617 Single-cell multidimensional profiling of tumor cell heterogeneity in supratentorial ependymomas

Jeong, D.; Danielli, S. G.; Maass, K. K.; Ghasemi, D. R.; Tetzlaff, S. K.; Reyhan, E.; Oliveira de Biagi-Junior, C. A.; Neyazi, S.; Nascimento, A.; Haase, R.; Lo Cascio, C.; Englinger, B.; Jiang, L.; Nguyen, C. M.; Baumgartner, A. C.; Castellani, S.; Rozowsky, J. S.; Hack, O. A.; Shaw, M. L.; Lotsch-Gojo, D.; Bruckner, K.; Pfister, S. M.; Kool, M.; Nowakowski, T. J.; Gojo, J.; Baird, L.; Alexandrescu, S.; Pajtler, K. W.; Venkataramani, V.; Filbin, M. G.

10.1101/2024.08.07.607066 — cancer biology — Posted on 2024-08-09

3618 Renal cancer cells acquire immune surface protein through trogocytosis and horizontal gene transfer

Marcarian, H. Q.; Sivakoses, A.; Arias, A. M.; Ihedioha, O.; Bishop, M. C.; Lee, B. R.; Bothwell, A. L. M.

10.1101/2024.08.07.607036 — cancer biology — Posted on 2024-08-09

3619 Adherence to the conservation of momentum to elucidate membrane transporter mechanisms.

Yorke, B. A.; Ginn, H. M.

10.1101/2024.08.07.607056 — biophysics — Posted on 2024-08-09

3620 Turning a Kv channel into hot and cold receptor by perturbing its electromechanical coupling.

Pinto-Anwandter, B. I.; Bassetto, C. A. Z.; Latorre, R.; Bezanilla, F.

10.1101/2024.08.08.607202 — biophysics — Posted on 2024-08-09

3621 Generating Multi-state Conformations of P-type ATPases with a Diffusion Model

Xu, J.; Wang, Y.

10.1101/2024.08.07.607107 — biophysics — Posted on 2024-08-09

3622 Structure and function of the human apoptotic scramblase Xkr4

Accardi, A.; Chakraborty, S.; Feng, Z.; Lee, S.; Alvarenga, O. E.; Panda, A.; Bruni, R.; Khelashvili, G.; Gupta, K.

10.1101/2024.08.07.607004 — biophysics — Posted on 2024-08-09

3623 HuTAge: a Comprehensive Human Tissue- and Cell-specific Ageing Signature Atlas

Himori, K.; Zhang, B.; Hatta, K.; Matsui, Y.

10.1101/2024.08.07.606269 — bioinformatics — Posted on 2024-08-09

3624 A Framework of Multi-View Machine Learning for Biological Spectral Unmixing of Fluorophores with Overlapping Excitation and Emission Spectra

Wang, R.; Feng, Y.; Valm, A. M.

10.1101/2024.08.07.607102 — bioinformatics — Posted on 2024-08-09

3625 A deep generative model for capturing cell to phenotype relationships

Weinberger, E.; Yu, P.; Lee, S.-I.

10.1101/2024.08.07.606396 — bioinformatics — Posted on 2024-08-09

3626 DeepReweighting: Reparameterizing Force Field under Explainable Deep Learning Framework

Chen, H.; Zhu, J.; Li, Z.

10.1101/2024.08.07.607110 — bioinformatics — Posted on 2024-08-09

3627 TRCompDB: A reference of human tandem repeat sequence and composition variation from long-read assemblies

Gu, B.; Chaisson, M.

10.1101/2024.08.07.607105 — bioinformatics — Posted on 2024-08-09

3628 Optimizing the detection of biological signals through a semi-automated feature selection tool

Arini, G.; Mencucini, L. G. S.; de Felicio, R.; Feitosa, L. G. P.; Rezende-Teixeira, P.; Tsuji, H.; Pilon, A.; Pinto, D. R.; Costa-Lotufo, L. V.; Lopes, N. P.; Trivella, D. B.; da Silva, R. R.

10.1101/2024.08.07.607073 — bioinformatics — Posted on 2024-08-09

3629 Retinal thermometry in-vivo using phase-sensitive optical coherence tomography

Zhuo, Y.; Bhuckory, M. B.; Li, H.; Junya, H.; Pham-Howard, D.; Veysset, D.; Ling, T.; Palanker, D.

10.1101/2024.08.07.607046 — bioengineering — Posted on 2024-08-09

3630 Microfluidic creep experiment for measuring linear viscoelastic mechanical properties of microparticles in a cross-slot extensional flow device

Ghanbarpour Mamaghani, S.; Dahl, J. B.

10.1101/2024.08.07.607090 — bioengineering — Posted on 2024-08-09

3631 HCM-associated mutations in MYH6/7 drive pathologic expression of TGF-β1 in cardiomyocytes within weeks of developmental specification

Hsieh, J.; Hall, M.; Shameem, M.; Ernst, P.; Kamdar, F.; Singh, B.; Meisel, R.; Ogle, B. M.

10.1101/2024.08.08.606705 — bioengineering — Posted on 2024-08-09

3632 The open to closed D-loop conformational switch determines length in filopodia-like actin bundles

Gadsby, J. R.; Savvas Ioannou, P.; Butler, R.; Mason, J.; Smith, A.; Dobramysl, U.; Chin, S.; Dobson, C.; Gallop, J.

10.1101/2024.08.09.607305 — biochemistry — Posted on 2024-08-09

3633 Identity-by-descent (IBD) segment outlier detection in endogamous populations using pedigree cohorts

Tan, S. J. S.; Dang, H. T.; Keim, S.; Bucan, M.; Mathieson, S.

10.1101/2024.08.07.607051 — genomics — Posted on 2024-08-09

3634 Nearly complete genome assembly of a critically endangered pine illuminates evolution and conservation of conifers

Zhang, R.-G.; Liu, H.; Shu, H.; Liu, D.-T.; Shang, H.-Y.; Jia, K.-H.; Wang, X.-Q.; Sun, W.-B.; Zhao, W.; Ma, Y.-P.

10.1101/2024.08.07.607108 — genomics — Posted on 2024-08-09

3635 Expanding kinetoplastid genome annotation through protein structure comparison

Trinidad-Barnech, J. M.; Sotelo-Silveira, J.; Fernandez Do Porto, D.; Smircich, P.

10.1101/2024.08.07.607044 — genomics — Posted on 2024-08-09

3636 Mixed outcomes in recombination rates after domestication: Revisiting theory and data

Bursell, M.; Rohilla, M.; Ramirez, L.; Cheng, Y.; Schwarzkopf, E. J.; Guerrero, R. F.; Heil, C. S.

10.1101/2024.08.07.607048 — evolutionary biology — Posted on 2024-08-09

3637 Revealing unseen dynamical regimes of ecosystems from population time-series data

Medeiros, L. P.; Sorenson, D. K.; Johnson, B. J.; Palkovacs, E. P.; Munch, S. B.

10.1101/2024.08.07.607005 — ecology — Posted on 2024-08-09

3638 Diet driven differences in host tolerance are linked to shifts in global gene expression in a common avian host-pathogen system

Sauer, E. L.; Stacy, C.; Perrine, W.; Love, A. C.; Lewis, J. A.; DuRant, S. E.

10.1101/2024.08.07.607042 — ecology — Posted on 2024-08-09

3639 Mapping Eelgrass Cover and Biomass at Izembek Lagoon, Alaska, Using In-situ Field Data and Sentinel-2 Satellite Imagery

Douglas, D. C.; Fleming, M. D.; Patil, V. P.; Ward, D. H.

10.1101/2024.08.07.607047 — ecology — Posted on 2024-08-09

3640 Material Properties Of The Embryonic Small Intestine During Buckling Morphogenesis

Gao, J.; Martin, L. G.; Loffet, E. A.; Durel, J. F.; Oikonomou, P.; Nerurkar, N.

10.1101/2024.08.07.606927 — developmental biology — Posted on 2024-08-09

3641 Retinoic acid breakdown is required for proximodistal positional identity during amphibian limb regeneration

Duerr, T. J.; Miller, M.; Kumar, S.; Bakr, D.; Griffiths, J. R.; Gautham, A. K.; Douglas, D.; Voss, S. R.; Monaghan, J. R.

10.1101/2024.08.07.607055 — developmental biology — Posted on 2024-08-09

3642 Analysis of oogenesis defects in Dyro mutant of Drosophila melanogaster.

Shima, T.; Kawabata, Y.; Yagi, Y.

10.1101/2024.08.07.607114 — developmental biology — Posted on 2024-08-09

3643 Cellular context specific tuning of actomyosin ring contractility within a common cytoplasm

Linehan, J.; Zampetaki, A.; Werner, M.; Heck, B.; Maddox, P.; Furthauer, S.; Maddox, A. S.

10.1101/2024.08.08.607200 — cell biology — Posted on 2024-08-09

3644 A minimal mathematical model for polarity establishment and centralsplindlin-independent cytokinesis

Maxian, O.; Longhini, K.; Glotzer, M.

10.1101/2024.08.07.607072 — cell biology — Posted on 2024-08-09

3645 Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis

Kim, A.; McMullen, M. R.; Bellar, A.; Streem, D.; Dasarathy, J.; Welch, N.; Dasarathy, S.

10.1101/2024.08.07.607014 — immunology — Posted on 2024-08-09

3646 Overventilation-induced airspace acidification increases susceptibility to Pseudomonas pneumonia

Felten, M.; Tan, C.; Ferencik, S.; Li, J.; Letsiou, E.; Lienau, J.; Muller-Redetzky, H.; Hocke, A.; Bromel, T. C.; Gruber, A. D.; Krishnamoorthy, G.; Ochs, M.; Brandenberger, C.; Zhang, Q.; Kuebler, W. M.; Witzenrath, M.

10.1101/2024.08.07.603041 — immunology — Posted on 2024-08-09

3647 GPR43 in Eosinophils Prevents the Emergence of Pathogenic Siglec-Fhi Neutrophils in Allergic Airway Inflammation

Yu, J.; Kim, S.; Song, H.-S.; Kim, H.-Y.; Kim, Y.-M.

10.1101/2024.08.07.607109 — immunology — Posted on 2024-08-09

3648 Outer hair cells stir cochlear fluids

Lee, C.; Shokrian, M.; Henry, K. S.; Carney, L.; Holt, J. C.; Nam, J.-H.

10.1101/2024.08.07.607009 — neuroscience — Posted on 2024-08-09

3649 Selective injury of thalamocortical tract in neonatal rats impairs forelimb use: modelvalidation and behavioral effects

Wen, T. C.; Corkrum, M.; Carmel, J. B.

10.1101/2024.08.07.607003 — neuroscience — Posted on 2024-08-09

3650 Effects of serotonergic psychedelics on synaptogenesis and immediate early genes expression - comparison with ketamine, fluoxetine and lithium

Vella, Y.; Syrova, K.; Petruskova, A.; Koutrouli, I.; Kutna, V.; Pala, J.; Nikolic, M.; Sichova, K.; Mazoch, V.; Jurok, R.; Kuchar, M.; Bendova, Z.; Palenicek, T.

10.1101/2024.08.07.606965 — neuroscience — Posted on 2024-08-09

3651 Impaired neurogenesis and synaptogenesis in iPSC-derived Parkinson's patient cortical neurons with D620N VPS35 mutation

Scheller, U.; Lee, C.; Seibler, P.; Mitkovski, M.; Rhee, J.; van Riesen, C.

10.1101/2024.08.07.606995 — neuroscience — Posted on 2024-08-09

3652 Targeted Time-Varying Functional Connectivity

Alonso, S.; Cocchi, L.; Hearne, L. J.; Shine, J. M.; Vidaurre, D.

10.1101/2024.08.07.606804 — neuroscience — Posted on 2024-08-09

3653 The effect of performance contingent reward prospects flexibly adapts to more versus less specific task goals

Liegel, N.; Schneider, D.; Wascher, E.; Klatt, L.-I.; Arnau, S.

10.1101/2024.08.07.607018 — neuroscience — Posted on 2024-08-09

3654 Stability of cross-sensory input to primary somatosensory cortex across experience

Kato, D. D.; Bruno, R. M.

10.1101/2024.08.07.607026 — neuroscience — Posted on 2024-08-09

3655 Conclusions about Neural Network to Brain Alignment are Profoundly Impacted by the Similarity Measure

Soni, A.; Srivastava, S.; Khosla, M.; Kording, K. P.

10.1101/2024.08.07.607035 — neuroscience — Posted on 2024-08-09

3656 Deep learning-based automated prediction of mouse seminiferous tubule stage by using bright-field microscopy

Tokuoka, Y.; Endo, T.; Morikura, T.; Hiradate, Y.; Ikawa, M.; Funahashi, A.

10.1101/2024.08.07.606973 — systems biology — Posted on 2024-08-09

3657 scACCorDiON: A clustering approach for explainable patient level cell cell communication graph analysis

Nagai, J. S.; Schaub, M. T.; Gesteira Costa Filho, I.

10.1101/2024.08.07.606989 — systems biology — Posted on 2024-08-09

3658 Predicting the Pathway Involvement of Metabolites in Both Pathway Categories and Individual Pathways

Huckvale, E. D.; Moseley, H. N. B.

10.1101/2024.08.07.607025 — systems biology — Posted on 2024-08-09

3659 Temporal changes in surface tension guide the accurate asymmetric division of Arabidopsis zygotes

Kang, Z.; Nakagawa, S.; Matsumoto, H.; Ishimoto, Y.; Nonoyama, T.; Hanaki, Y.; Tsugawa, S.; Ueda, M.

10.1101/2024.08.07.605794 — plant biology — Posted on 2024-08-09

3660 CRISPR-Cas9 mediated deletions of FvMYB46 reduces fruit set and biosynthesis of flavonoids in Fragaria vesca

Rai, A.; Skarn, M. N.; Tengs, T.; Elameen, A.; Amundsen, M. R.; Bjora, O. S.; Haugland, L. K.; Yakovlev, I. A.; Brurberg, M. B.; Thorstensen, T.

10.1101/2024.08.07.607017 — plant biology — Posted on 2024-08-09

3661 On the rate-limiting dynamics of force development in muscle

van der Zee, T. J.; Wong, J. D.; Kuo, A. D.

10.1101/2024.08.07.606988 — physiology — Posted on 2024-08-09

3662 UltraTimTrack: a Kalman-filter-based algorithm to track muscle fascicles in ultrasound image sequences

van der Zee, T. J.; Tecchio, P.; Hahn, D.; Raiteri, B. J.

10.1101/2024.08.07.607010 — physiology — Posted on 2024-08-09

3663 Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress

Castillo-Ramirez, L. A.; Ryu, S.; De Marco, R. J.

10.1101/2024.08.07.606983 — physiology — Posted on 2024-08-09

3664 Multi-Coloured Sequential Resonance Energy Transfer for Simultaneous Ligand Binding at G Protein-Coupled Receptors

Valentini, A.; Dibnah, B.; Ciba, M.; Ulven, T.; Hudson, B. D.; Rexen Ulven, E.

10.1101/2024.08.07.606978 — pharmacology and toxicology — Posted on 2024-08-09

3665 Prevalence and associated risk factors assessment of bovine fasciolosis in and around Bahir Dar, Ethiopia

Temesgen, A. B.; Mesfin, T.

10.1101/2024.08.07.606800 — pathology — Posted on 2024-08-09

3666 Single-shot impulsive stimulated Brillouin microscopy by tailored ultrashort pulses

Krause, D.; Boehm, J.; Liebig, L.; Koukourakis, N.; Czarske, J.

10.1101/2024.08.07.606954 — biophysics — Posted on 2024-08-09

3667 Research on the Mechanism of Lphn1 Knockout in Inhibiting Colorectal Cancer

wang, Y.

10.1101/2024.08.07.606975 — bioinformatics — Posted on 2024-08-09

3668 Boundary-Sensing Mechanism in Branched Microtubule Networks

Zaferani, M.; Song, R.; Wingreen, N. S.; Stone, H. A.; Petry, S.

10.1101/2024.08.07.606992 — bioengineering — Posted on 2024-08-09

3669 Epigenetic clock and lifespan prediction in the short-lived killifish Nothobranchius furzeri

Giannuzzi, C.; Baumgart, M.; Neri, F.; Cellerino, A.

10.1101/2024.08.07.606986 — genomics — Posted on 2024-08-09

3670 Hematophagy generates a convergent genomic signature in mosquitoes and sandflies

Devilliers, J.; Warren, B.; Rosato, E.; Kyriacou, C.; Feuda, R.

10.1101/2024.08.07.607008 — evolutionary biology — Posted on 2024-08-09

3671 Releasing the octoPus, an open-source digital tool to promote Integrated Pest Management

Bregaglio, S. U. M.; Rossi, E.; Ascari, L.; Mongiano, G.; Del Cavallo, E.; Bajocco, S.; Manici, L. M.; Pepe, A. G.; Bassi, C.; Tiso, R.; Pietrangeli, F.; Cattaneo, G.; Nigro, C.; Gerardi, M. S.; Bussotti, S.; Sanchioni, A.; Tognetti, D.; Sandra, M.; De Lillo, I.; Framarin, P.; Di Ferdinando, S.; Bugiani, R.

10.1101/2024.08.07.606987 — ecology — Posted on 2024-08-09

3672 Neuropeptide oxytocin facilitates its own brain-to-periphery uptake by regulating blood flow dynamics and permeability

Rajamannar, P.; Raz, O.; Levkowitz, G.

10.1101/2024.08.07.606980 — neuroscience — Posted on 2024-08-09

3673 All-Diamond Boron-Doped Microelectrodes for Neurochemical Sensing with Fast-Scan Cyclic Voltammetry

Gupta, B.; Kepros, B.; Landgraf, J. B.; Becker, M. F.; Li, W.; Purcell, E. K.; Siegenthaler, J. R.

10.1101/2024.08.07.606919 — neuroscience — Posted on 2024-08-09

3674 Plasmid carriage and the unorthodox use of fitness in microbiology

Reding, C.

10.1101/810259 — evolutionary biology — Posted on 2024-08-09

3675 Sound preferences in mice are sex-dependent

Sehrawat, K.; Nelken, I.

10.1101/2024.08.04.606510 — neuroscience — Posted on 2024-08-09

3676 Circular RNA HMGCS1 sponges miR-4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

Zhang, M.; Du, G.; Xie, L.; Xu, Y.; Chen, W.

10.1101/2024.03.06.583717 — cell biology — Posted on 2024-08-09

3677 An outbreak of canine coronavirus type 2 in captive snow leopards (Panthera uncia) demonstrates a possible role for felids as mixing vessels for alphacoronaviruses

Olarte-Castillo, X. A.; Schlecht, A. B.; Calle, P. P.; Whittaker, G. A.

10.1101/2024.03.25.586607 — microbiology — Posted on 2024-08-09

3678 Chromatin conformation dynamics during CD4+ T cell activation implicates autoimmune disease-associated genes and regulatory elements

Pahl, M. C.; Sharma, P.; Thomas, R. M.; Thompson, Z.; Mount, Z.; Pippin, J.; Morawski, P. A.; Su, C.; Campbell, D. J.; Grant, S. F.; Wells, A. D.

10.1101/2023.04.05.535731 — immunology — Posted on 2024-08-09

3679 Reduced perceptual error monitoring in autism

Zuk, N. J.; Weiss, Y.; Akrami, A.; Ahissar, M.

10.1101/2024.07.23.604831 — neuroscience — Posted on 2024-08-09

3680 Multimodal mismatch responses in mouse auditory cortex

Solyga, M.; Keller, G. B.

10.1101/2023.10.29.564593 — neuroscience — Posted on 2024-08-09

3681 Linking brain-heart interactions to emotional arousal in immersive virtual reality

Fourcade, A.; Klotzsche, F.; Hofmann, S. M.; Mariola, A.; Nikulin, V.; Villringer, A.; Gaebler, M.

10.1101/2024.01.04.574165 — neuroscience — Posted on 2024-08-09

3682 Macroscale traveling waves evoked by single-pulse stimulation of the human brain

Campbell, J. M.; Davis, T. S.; Nesterovich Anderson, D.; Arain, A.; Davis, Z.; Inman, C. S.; Smith, E. H.; Rolston, J. D.

10.1101/2023.03.27.534002 — neuroscience — Posted on 2024-08-09

3683 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.

10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-09

3684 A variant centric analysis of allele sharing in dogs and wolves

Funk, M. W.; Kidd, J. M.

10.1101/2024.08.08.607131 — genomics — Posted on 2024-08-08

3685 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Xu, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Bian, X.; Wei, Z.; Kummerli, R.; Li, Z.

10.1101/2023.10.30.564663 — genomics — Posted on 2024-08-09

3686 Cspg4 sculpts oligodendrocyte precursor cell morphology

Bromley-Coolidge, S.; Iruegas, D.; Appel, B.

10.1101/2024.08.08.607226 — developmental biology — Posted on 2024-08-08

3687 Non-essential kinetochore proteins contribute to meiotic chromosome condensation through polo-like kinase

Trakroo, D.; Agarwal, P.; Alekar, A.; Ghosh, S. K.

10.1101/2023.10.24.563891 — cell biology — Posted on 2024-08-09

3688 Local neurovascular coupling in the amygdala is responsible for context-dependent emotional adjustment

Ruan, J.; Quan, X.; Xie, H.; Zhang, Y.; Zhang, D.; Wang, W.; Zhao, B.; Lu, D.; Jia, J.-M.

10.1101/2023.02.13.527949 — neuroscience — Posted on 2024-08-09

3689 Reduced gene dosage of the psychiatric risk gene Cacna1c is associated with impairments in hypothalamic-pituitary-adrenal axis activity in rats

Moon, A.; Mawson, E.; Gasalla Canto, P.; Wilkinson, L.; Dwyer, D.; Thomas, K. L.; Hall, J.

10.1101/2024.08.08.607145 — neuroscience — Posted on 2024-08-08

3690 Deletion of endocannabinoid synthesizing enzyme DAGLα from cerebellar Purkinje cells decreases social preference and elevates anxiety

Smith, G.; McCoy, K.; Viana Di Prisco, G.; Kuklish, A.; Grant, E.; Bhat, M.; Atwood, B.; Mackie, K.; Kalinovsky, A.

10.1101/2024.08.08.607068 — neuroscience — Posted on 2024-08-08

3691 No single PCR test is sufficient to determine parvovirus IHHNV presence in or impact on farmed shrimp production

Sritunyalucksana, K.; Sanguanrut, P.; Srisala, J.; Thawonsuwan, J.; Saleetid, N.; Vanichviriyakit, R.; Chotwiwatthanakun, C.; FLEGEL, T. W.; Taengchaiyaphum, S.

10.1101/2023.09.08.556791 — zoology — Posted on 2024-08-08

3692 Meta-analysis of public RNA-sequencing data of drought and salt stresses in different phenotypes of Oryza sativa

Shintani, M.; Bono, H.

10.1101/2024.08.06.605779 — plant biology — Posted on 2024-08-08

3693 The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract

Pineros, L.; Frolov, N.; Ruiz-Reynes, D.; Van Eynde, A.; Cavin-Meza, G. J.; Heald, R.; Gelens, L.

10.1101/2024.07.28.605512 — biophysics — Posted on 2024-08-08

3694 Kinetics and optimality of influenza A virus locomotion

Agarwal, S.; Veytsman, B.; Fletcher, D.; Huber, G.

10.1101/2024.05.06.592729 — biophysics — Posted on 2024-08-08

3695 Crystal Structure of the 4-Hydroxybutyryl-CoA Synthetase (ADP-forming) from Nitrosopumilus maritimus

Johnson, J. A.; Tolar, B. B.; Tosun, B.; Yoshikuni, Y.; Francis, C. A.; Wakatsuki, S.; Demirci, H.

10.1101/2023.07.14.549078 — biophysics — Posted on 2024-08-08

3696 gtfsort: a tool to efficiently sort GTF files

Gonzales-Irribarren, A.; Fu, A.

10.1101/2023.10.21.563454 — bioinformatics — Posted on 2024-08-08

3697 Deep Generative Models of Protein Structure Uncover Distant Relationships Across a Continuous Fold Space

Draizen, E. J.; Veretnik, S.; Mura, C.; Bourne, P. E.

10.1101/2022.07.29.501943 — bioinformatics — Posted on 2024-08-08

3698 Visual analysis of spatial transcriptomics data with RedeViz

Wang, D.; Ren, X.

10.1101/2024.07.09.602652 — bioinformatics — Posted on 2024-08-08

3699 Generative AI for Cardiac Organoid Florescence Generation

Kandula, A. K. R.; Phamornratanakun, T.; Gomez, A. H.; El-Mokahal, M.; Ma, Z.; Feng, Y.; Yang, H.

10.1101/2024.01.15.575724 — bioengineering — Posted on 2024-08-08

3700 Dual-Action Kinase Inhibitors Influence p38α MAP Kinase Dephosphorylation

Stadnicki, E.; Ludewig, H.; Kumar, R. P.; Wang, X.; Qiao, Y.; Kern, D.; Bradshaw, N.

10.1101/2024.05.15.594272 — biochemistry — Posted on 2024-08-08

3701 Comparative analysis of tardigrade locomotion across life stage, species, and pharmacological treatment

Anderson, E. M.; Houck, S. G.; Conklin, C. L.; Tucci, K. L.; Rodas, J. D.; Mori, K. E.; Armstrong, L. J.; Illingworth, V. B.; Lo, T.-W.; Woods, I. G.

10.1101/2024.05.24.595396 — animal behavior and cognition — Posted on 2024-08-08

3702 Learning sequence-based regulatory dynamics in single-cell genomics

Ibarra, I. L.; Schneeberger, J.; Erdogan, E.; Redl, L.; Martens, L.; Klein, D.; Aliee, H.; Theis, F. J.

10.1101/2024.08.07.605876 — genomics — Posted on 2024-08-08

3703 Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy

Lichauco, C.; Foss, E. J.; Gatbonton-Schwager, T.; Athow, N. F.; Lofts, B.; Acob, R.; Taylor, E.; Marquez, J. J.; Lao, U.; Miles, s.; Bedalov, A.

10.1101/2024.03.21.586113 — genetics — Posted on 2024-08-08

3704 Loss of cped1 does not affect bone and lean mass in zebrafish

Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.

10.1101/2024.07.10.601974 — genetics — Posted on 2024-08-08

3705 Mint/X11 PDZ domains from non-bilaterian animals recognize and bind CaV2 calcium channel C-termini in vitro .

Harracksingh, A. N.; Singh, A.; Mayorova, T.; Bejoy, B.; Hornbeck, J.; Elkhatib, W.; McEdwards, G.; Gauberg, J.; Taha, A. R. W.; Islam, I. M.; Erclik, T.; Currie, M. A.; Noyes, M.; Senatore, A.

10.1101/2024.02.26.582151 — evolutionary biology — Posted on 2024-08-08

3706 RoAM: computational reconstruction of ancient methylomes and identification of differentially methylated regions

Mathov, Y.; Rosen, N.; Leibson, C.; Meshorer, E.; Yakir, B.; Carmel, L.

10.1101/2024.08.08.607143 — evolutionary biology — Posted on 2024-08-08

3707 Urban Cepaea nemoralis snails are less likely to have nematodes trapped within their shells

Dahirel, M.; Reyne, H.; De Wolf, K.; Bonte, D.

10.1101/2024.03.07.583959 — ecology — Posted on 2024-08-08

3708 Geographic variation in vulnerability to warming temperatures in an intertidal barnacle species

Gilman, S.; Ober, G. T.; Rognstad, R. L.; Bunnenberg-Ross, M.; Man, T.

10.1101/2024.03.26.586848 — ecology — Posted on 2024-08-08

3709 An atypical basement membrane forms a midline barrier during left-right asymmetric gut development in the chicken embryo

Demler, C. A.; Lawlor, J. C.; Yelin, R.; Llivichuzcha-Loja, D.; Shaulov, L.; Kim, D. S.; Stewart, M. A.; Lee, F.; Shylo, N. A.; Trainor, P.; Schultheiss, T. M.; Kurpios, N. A.

10.1101/2023.08.15.553395 — developmental biology — Posted on 2024-08-08

3710 Ligand-Dependent Mechanisms of C-C Chemokine Receptor 5 (CCR5) Trafficking Revealed by APEX2 Proximity Labeling Proteomics

Gu, S.; Maurya, S.; Lona, A.; Borrega-Roman, L.; Salanga, C.; Gonzalez, D. J.; Kufareva, I.; Handel, T.

10.1101/2023.11.01.565224 — cell biology — Posted on 2024-08-08

3711 Geometrical determinant of nonlinear synaptic integration in human cortical pyramidal neurons

Yoon, J.

10.1101/2024.07.14.601255 — neuroscience — Posted on 2024-08-08

3712 Astrocyte Regulation of Synaptic Plasticity Balances Robustness and Flexibility of Cell Assemblies

Koshkin, R.; Fukai, T.

10.1101/2024.08.08.607120 — neuroscience — Posted on 2024-08-08

3713 LitGene: a transformer-based model that uses contrastive learning to integrate textual information into gene representations

Jararweh, A.; Macaulay, O.; Arredondo, D.; Oyebamiji, O.; Hu, Y.; Tafoya, L.; Zhang, Y.; Virupakshappa, K.; Sahu, A.

10.1101/2024.08.07.606674 — bioinformatics — Posted on 2024-08-08

3714 Improved detection of microbiome-disease associations via population structure-aware generalized linear mixed effects models (microSLAM)

Goldman, M.; Zhao, C.; Pollard, K. S.

10.1101/2024.06.27.600934 — bioinformatics — Posted on 2024-08-08

3715 HiExM: high-throughput expansion microscopy enables scalable super-resolution imaging

Day, J. H.; Della Santina, C. M.; Maretich, P.; Auld, A. L.; Schneider, K. K.; Shin, T.; Boyden, E. S.; Boyer, L. A.

10.1101/2023.02.07.527509 — bioengineering — Posted on 2024-08-08

3716 Histone variant H3.3 mediates cGAS-STING pathway activation via telomere deprotection

Huang, C.-M.; Chen, L.-Y.

10.1101/2024.08.07.606966 — molecular biology — Posted on 2024-08-08

3717 Phlorotannin rich Ascophyllum nodosum seaweed extract inhibits influenza infection

Mega, D. F.; Sharma, P.; Kipar, A.; Hetzel, U.; Bramwell, C.; Meritt, A.; Wright, S.; Plummer, C.; Urbanowicz, R. A.; Stewart, J. P.

10.1101/2024.08.08.606782 — microbiology — Posted on 2024-08-08

3718 Plasmid-chromosome transcriptional crosstalk in multidrug resistant clinical enterobacteria

Toribio-Celestino, L.; Calvo-Villamanan, A.; Herencias, C.; Alonso-del Valle, A.; Sastre-Dominguez, J.; Quesada, S.; Mazel, D.; Rocha, E. P. C.; Fernandez-Calvet, A.; San Millan, A.

10.1101/2024.08.08.607126 — microbiology — Posted on 2024-08-08

3719 Rapid Nanopore cloud-based monitoring and analysis of commercial aquaculture microbiomes

Strutt, J. P. B.; Bessarab, I.; Goh, J. Y. M.; Marican, H.; Summers, S.

10.1101/2024.08.07.607111 — microbiology — Posted on 2024-08-08

3720 Development of a MicH-specific immunoassay for MIC detection and diagnosis

Lahme, S.; Mantilla Aguas, J.

10.1101/2024.08.08.607177 — microbiology — Posted on 2024-08-08

3721 Individual patterns of functional connectivity in neonates as revealed by surface-based Bayesian modeling

Derman, D.; Pham, D. D.; Mejia, A. F.; Ferradal, S. L.

10.1101/2023.07.24.550218 — neuroscience — Posted on 2024-08-08

3722 Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice

McFadden, S. A.; Peck, M. R.; Sime, L. N.; Cox, M. F.; Ikiz, E. D.; Findley, C. A.; Quinn, K.; Fang, Y.; Bartke, A.; Hascup, E. R.; Hascup, K. N.

10.1101/2024.03.26.586836 — neuroscience — Posted on 2024-08-08

3723 Insights into the role of dopamine in rhizosphere microbiome assembly

Ding, Y.; Vogel, H. K.; Zhai, Y.; Carlson, H. K.; Andeer, P. F.; Novak, V.; Kim, N.; Bowen, B. P.; Golini, A. N.; Kosina, S. M.; Coleman-Derr, D.; Vogel, J. P.; Northen, T. R.

10.1101/2024.08.07.607067 — plant biology — Posted on 2024-08-08

3724 Composite impact of genome-wide APOBEC mutations and HLA haplotype on cancer immunogenicity has a sex-biased survival impact

Larijani, M.; Borzooee, F.; Heravi-Moussavi, A.

10.1101/2024.08.07.607038 — cancer biology — Posted on 2024-08-08

3725 A Versatile Antibody Capture System that Drives Precise In Vivo Delivery of mRNA loaded Lipid Nanoparticles and Enhances Gene Expression

Chen, M.; Yuen, D.; McLeod, V. M.; Yong, K. W.; Smyth, C. H.; Rossi Herling, B.; Payne, T.; Fabb, S.; Belousoff, M. J.; Algarni, A.; Sexton, P. M.; Porter, C. J. H.; Pouton, C. W.; Johnston, A. P. R.

10.1101/2024.08.07.607101 — bioengineering — Posted on 2024-08-08

3726 Dynamics and Evolutionary Conservation of B Complex Protein Recruitment During Spliceosome Activation

Fu, X.; Hoskins, A. A.

10.1101/2024.08.08.606642 — biochemistry — Posted on 2024-08-08

3727 Mechanism of ASF1 Inhibition by CDAN1

Sedor, S. F.; Shao, S.

10.1101/2024.08.08.607204 — biochemistry — Posted on 2024-08-08

3728 CD38 mediates nicotinamide mononucleotide (NMN) base exchange to yield nicotinic acid mononucleotide (NaMN)

Madawala, R.; Banks, J. L.; Hancock, S. E.; Quek, L.-E.; Turner, N.; Wu, L. E.

10.1101/2024.08.08.607247 — biochemistry — Posted on 2024-08-08

3729 Structural basis of human 20S proteasome biogenesis

Zhang, H.; Zhou, C.; Mohammad, Z. S.; Zhao, J.

10.1101/2024.08.08.607236 — biochemistry — Posted on 2024-08-08

3730 Top-down Proteomics for the Characterization and Quantification of Calreticulin Arginylation

Searfoss, R. M.; Liu, X.; Garcia, B. A.; Lin, Z.

10.1101/2024.08.08.607245 — biochemistry — Posted on 2024-08-08

3731 Detection of genome structural variation in normal cells and tissues by single molecule sequencing

Heid, J.; Huang, Z.; Lee, M.; Makhortov, S.; Pan, E.; Montagna, C.; Sun, S. Y.; Vijg, J.; Maslov, A. Y.

10.1101/2024.08.08.607188 — genomics — Posted on 2024-08-08

3732 The spatial spread and the persistence of gene drives are affected by demographic feedbacks, density dependence and Allee effects

Kläy, L.; Girardin, L.; Calvez, V.; Debarre, F.

10.1101/2024.08.08.607064 — genetics — Posted on 2024-08-08

3733 Mechanistic basis of lineage restriction

Wu, B.; Lee, J. H.; Foshay, K. M.; Zhang, L.; Fernandes, C. J.; Gao, B.; Dou, X.; Zhang, C. Z.; Fan, G.; Xiao, B. X.; Lahn, B. T.

10.1101/2024.08.07.606262 — developmental biology — Posted on 2024-08-08

3734 FACT-(H3-H4) complex stimulates Pol activity to coordinate DNA synthesis with nucleosome assembly

Zhang, W.; Xu, J.; Yang, J.; Shi, G.; Wu, J.; Gao, N.; Feng, J.; Li, Q.

10.1101/2024.08.08.607175 — molecular biology — Posted on 2024-08-08

3735 Reanalysis of cryo-EM data reveals ALK-cytokine assemblies with distinct stoichiometries

Felix, J.; De Munck, S.; Bazan, J. F.; Savvides, S. N.

10.1101/2024.08.08.607122 — molecular biology — Posted on 2024-08-08

3736 Biallelic Loss of Molecular Chaperone Molecule AIP Results in a Novel Severe Multisystem Disease Defined by Defective Proteostasis

Korbonits, M.; Wang, X.; Barry, S.; Lim, C.; Suleyman, O.; De-Tito, S.; Begum, N.; Vignola, M. L.; Hall, C.; Perna, L.; Chapple, P.; Henson, S.; Morales, V.; Bianchi, K.; Edvardsson, V. O.; Ragnarsson, K. A.; Kristinsdottir, V. E.; Debeer, A.; Sleyp, Y.; Zinchenko, R.; Anderson, G.; Duchen, M.; Singh, K.; Chung, C.-Y.; Yuan, Y.; Patel, S.; Aksoy, E.; Borovikov, A. O.; Bjornsson, H. T.; Van Esch, H.; Czibik, G.; Tooze, S.; Brennan, C. H.; Haworth, O.

10.1101/2024.08.08.604602 — molecular biology — Posted on 2024-08-08

3737 Clostridioides difficile Toxins Unhinged: Allosterically Switchable Network Orients β-flap

Finn, L. M.; Cummer, R.; Castagner, B.; Keller, B. G.

10.1101/2024.08.08.607137 — molecular biology — Posted on 2024-08-08

3738 Tunturi virus isolates and metagenome-assembled viral genomes provide insights into the virome of Acidobacteriota in Arctic tundra soils

Demina, T.; Marttila, H.; Pessi, I. S.; Mannisto, M. K.; Dutilh, B. E.; Roux, S.; Hultman, J.

10.1101/2024.08.08.607240 — microbiology — Posted on 2024-08-08

3739 Global distribution and diversity of haloarchaeal pL6-family plasmids

Dyall-Smith, M.; Pfeiffer, F.

10.1101/2024.08.07.607104 — microbiology — Posted on 2024-08-08

3740 The "DDVF" motif used by viral and bacterial proteins to hijack RSK kinases evolved as a mimic of a short linear motif (SLiM) found in proteins related to the RAS-ERK MAP kinase pathway.

Veinstein, M.; Stroobant, V.; Michiels, T.; Sorgeloos, F.

10.1101/2024.08.08.607128 — microbiology — Posted on 2024-08-08

3741 Commensal Yeast Promotes Salmonella Typhimurium Virulence

Jaswal, K.; Todd, O. A.; Flores Audelo, R. C.; Santus, W.; Paul, S.; Singh, M.; Miao, J.; Underhill, D. M.; Peters, B. M.; Behnsen, J.

10.1101/2024.08.08.606421 — microbiology — Posted on 2024-08-08

3742 The mammalian Ire1 inhibitor, 4μ8C, exhibits broad anti-Aspergillus activity in vitro and in a treatment model of fungal keratitis.

Kamath, M. M.; Adams, E. M.; Lightfoot, J. D.; Wells, B. L. L.; Fuller, K. K.

10.1101/2024.08.08.607189 — microbiology — Posted on 2024-08-08

3743 Design of a Soluble Multivalent Notch Agonist

Mout, R.; Jing, R.; Egan, E.; Eisenach, H.; Najia, M. A.; Hensch, L.; Bingham, T.; Kononov, M.; Gunage, R.; Zhao, Y.; Edman, N. I.; SCHLAEGER, T.; Zon, L. I.; North, T. E.; Lendahl, U.; Baker, D.; Blacklow, S.; Daley, G. Q.

10.1101/2024.08.07.607099 — synthetic biology — Posted on 2024-08-08

3744 A synthetic cell-free pathway for biocatalytic upgrading of one-carbon substrates

Landwehr, G. M.; Vogeli, B.; Tian, C.; Singal, B.; Gupta, A.; Lion, R.; Sargent, E. H.; Karim, A. S.; Jewett, M. C.

10.1101/2024.08.08.607227 — synthetic biology — Posted on 2024-08-08

3745 Potent LILRB1 D1D2-containing antibodies inhibit RIFIN-mediated immune evasions

Wang, Y.; Tang, H.; Wang, W.; Li, M.; Zhu, C.; Dai, H.; Zhao, H.; Wu, B.; Wang, J.

10.1101/2024.08.08.607148 — biochemistry — Posted on 2024-08-08

3746 Genomic sequencing to detect cross-breeding quality in dogs: an example studying disorders in sexual development

de Gennaro, L.; Burgio, M.; Lacalandra, G. M.; Petronella, F.; L'Abbate, A.; Ravasini, F.; Trombetta, B.; Rizzo, A.; Ventura, M.; Cicirelli, V.

10.1101/2024.08.07.606952 — genomics — Posted on 2024-08-08

3747 Differential requirement of m6A reader proteins, IGF2BP2 and HNRNPA2B1 for the processing of N6-methyladenosine modified H19 lncRNA: Stability versus miR-675 biogenesis

Somasundaram, K.; Jana, S.; Chowdhury, A.

10.1101/2024.08.07.606971 — cancer biology — Posted on 2024-08-08

3748 MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway

Maher, S.; Wynne, K.; Zhernovkov, V.; Halasz, M.

10.1101/2024.08.07.606961 — cancer biology — Posted on 2024-08-08

3749 PyPlaque: an Open-source Python Package for Phenotypic Analysis of Virus Plaque Assays

De, T.; Andriasyan, V.; Yakimovich, A.

10.1101/2024.08.07.603274 — bioinformatics — Posted on 2024-08-08

3750 Molecular Glue-Design-Evaluator (MOLDE): An Advanced Method for In-Silico Molecular Glue Design

Geoffrey A.S., B.; Agrawal, D.; Kulkarni, N.; Gunasekaran, M.

10.1101/2024.08.06.606937 — bioinformatics — Posted on 2024-08-08

3751 PLSKO: a robust knockoff generator to control false discovery rate in omics variable selection

Yang, G.; Menkhorst, E.; Dimitriadis, E.; Le Cao, K.-A.

10.1101/2024.08.06.606935 — bioinformatics — Posted on 2024-08-08

3752 Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size.

Fromm, B.; Sorger, T.

10.1101/2024.05.21.595052 — evolutionary biology — Posted on 2024-08-08

3753 Asymmetric genome merging leads to gene expression novelty through nucleo-cytoplasmic disruptions and transcriptomic shock in Chlamydomonas triploids

Prost-Boxoen, L.; Bafort, Q.; Van de Vloet, A.; Almeida-Silva, F.; Thet Paing, Y.; Casteleyn, G.; D'hondt, S.; De Clerck, O.; Van de Peer, Y.

10.1101/2024.08.06.604315 — evolutionary biology — Posted on 2024-08-08

3754 Long-term tree population growth can predict woody encroachment patterns

Shriver, R. K.; Pletcher, E.; Biondi, F.; Urza, A. K.; Weisberg, P. J.

10.1101/2024.04.07.588197 — ecology — Posted on 2024-08-08

3755 Using integrated wildlife monitoring for quantifying the impact of emerging Bagaza virus in red-legged partridges in Portugal, 2012-2024

Queiros, J.; Costa, J. B.; Mello, G.; Fontoura-Goncalves, C.; Hofle, U.; Gortazar, C.; Alves, P. C.; Acevedo, P.; Goncalves, D.

10.1101/2024.08.07.606962 — ecology — Posted on 2024-08-08

3756 Comparative attractiveness of Anopheles quadriannulatus and Anopheles arabiensis to humans estimated by comparing the relative abundance of these two species in larval samples, unbaited adult catches and human-baited adult catches.

Kavishe, D. R.; Walsh, K. A.; Msoffe, R. V.; Duggan, L. M.; Tarimo, L. J.; Butler, F.; Govella, N. J.; Kaindoa, E. W.; Killeen, G.

10.1101/2024.08.07.606970 — ecology — Posted on 2024-08-08

3757 Bacteria can anticipate the seasons: photoperiodism in cyanobacteria

Jabbur, M. L.; Johnson, C. H.

10.1101/2024.05.13.593996 — microbiology — Posted on 2024-08-08

3758 A Rose by any Other Name: Towards a quantitative theory of neuroimmune interactions

Fadai, N. T.; Turcanu, V.; Nicolau, D. V.

10.1101/2024.07.25.605114 — immunology — Posted on 2024-08-08

3759 Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.

Hoffner, G.; Castro, P.; Uhrig, L.; Signorelli, C. M.; Dupont, M.; Tasserie, J.; Destexhe, A.; Cofre, R.; Sitt, J.; Jarraya, B.

10.1101/2024.03.27.586806 — neuroscience — Posted on 2024-08-08

3760 Bridging the gap between presynaptic hair cell function and neural sound encoding

Jaime Tobon, L. M.; Moser, T.

10.1101/2022.10.19.512823 — neuroscience — Posted on 2024-08-08

3761 A sticky Poisson Hidden Markov Model for spike data

Li, T.; La Camera, G.

10.1101/2024.08.07.606969 — neuroscience — Posted on 2024-08-08

3762 Microsaccade direction reveals the variation in auditory selective attention processes

Yamagishi, S.; Furukawa, S.

10.1101/2024.08.07.606838 — neuroscience — Posted on 2024-08-08

3763 Patient-specific gene networks reveal novel subtypes and predictive biomarkers in lung cancer

Lopez-Sanchez, P.; Avila-Moreno, F.; Hernandez-Lemus, E.; Kuijjer, M. L.; Espinal-Enriquez, J.

10.1101/2024.08.06.606802 — systems biology — Posted on 2024-08-08

3764 Meta-analysis of public RNA-sequencing data of drought and salt stresses in different phenotypes of Oryza sativa

Shintani, M.; Bono, H.

10.1101/2024.08.06.605779 — plant biology — Posted on 2024-08-08

3765 Study on the phenotypic diversity and comprehensive evaluation analysis of 43 ornamental peonies of Sect. Paeonia.

Cao, H.; Xu, S.; Liu, M.; Jiang, S.; Ma, L.; Wu, J.; Zhang, X.; Kong, L.; Ren, W.; Liu, Z.; Chen, X.; Ma, W.; Liu, X.

10.1101/2024.08.06.606934 — plant biology — Posted on 2024-08-08

3766 Sexual receptivity increases in synchrony with the ovulatory cycle in female medaka

Tomihara, S.; Shimomai, R.; Nakajo, M.; Oka, Y.; Umatani, C.

10.1101/2024.08.06.606788 — physiology — Posted on 2024-08-08

3767 Two TAL effectors of Xanthomonas citri pv. malvacearum target GhSWEET15 as the susceptibility genes for bacterial blight of cotton

Shah, S. M. A.; Haq, F.; Huang, K.; Wang, Q.; Liu, L.; Li, Y.; Wang, Y.; Khan, A.; Yang, R.; Khojasteh, M.; Xu, X.; Xu, Z.; Chen, G.

10.1101/2024.08.06.606744 — pathology — Posted on 2024-08-08

3768 Deep lipidomic profiling reveals sex dimorphism of lipid metabolism in fibro-calcific aortic valve disease

Prabutzki, P.; Woelk, M.; Boettner, J.; Ni, Z.; Werner, S.; Thiele, H.; Schiller, J.; Buettner, P.; Schlotter, F.; Fedorova, M.

10.1101/2024.08.07.606946 — pathology — Posted on 2024-08-08

3769 Disruption of Circadian Clock Induces Abnormal Mammary Morphology and Aggressive Basal Tumorigenesis by Enhancing LILRB4 Signaling

Ogunlusi, O.; Sarkar, M.; Chakrabarti, A.; Boland, D.; Nguyen, T.; Sampson, J.; Nguyen, C.; Falis, D.; Jones-Hall, Y.; Fu, L.; Mallick, B.; Keene, A.; Jones, J.; Sarkar, T. R.

10.1101/2024.03.19.585534 — cancer biology — Posted on 2024-08-08

3770 Tokenized and Continuous Embedding Compressions of Protein Sequence and Structure

Lu, A. X.; Yan, W.; Yang, K. K.; Gligorijevic, V.; Cho, K.; Abbeel, P.; Bonneau, R.; Frey, N.

10.1101/2024.08.06.606920 — bioinformatics — Posted on 2024-08-08

3771 Accelerated Limbal Epithelial Differentiation of Human Induced Pluripotent Stem Cells Using a Defined Keratinocyte Serum-Free Medium

Roshandel, D.; Alvarez-Palomo, B.; Zaw, K.; Zhang, D.; Edel, M. J.; Wong, E. N.; Wiffen, S.; Chen, F. K.; Morgan, W. H.; McLenachan, S.

10.1101/2024.08.06.606916 — bioengineering — Posted on 2024-08-08

3772 A cytochrome bd repressed by a MarR family regulator confers resistance to metals, nitric oxide, sulfide, and cyanide in Chromobacterium violaceum

Batista, B. B.; Will, W. R.; de Lima, V. M.; Fang, F. C.; da Silva Neto, J. F.

10.1101/2024.08.06.606881 — microbiology — Posted on 2024-08-08

3773 SARM1 orthosteric base exchange inhibitors cause subinhibitory SARM1 activation

Leahey, R.; Weber, M.; Cho, C. H.; Hur, S.; Cramer, A.; Manzanares, K.; Babin, B.; Boenig, G.; Kring, T.; Liu, L.; Cui, Y.; Ganti, A.; Evans, J. P.; Nespi, M.; Ly, J.; Nugent, A. A.; Green, S.; Chan, B.; Hoogenraad, C. C.; Delwig, A.; Hinz, F. I.

10.1101/2024.08.06.606489 — neuroscience — Posted on 2024-08-08

3774 Adenosine signaling in glia modulates metabolic state-dependent behavior in Drosophila

De Backer, J.-F.; Karges, T.; Papst, J.; Coman, C.; Ahrends, R.; Xu, Y. Y.; Garcia-Ceceres, C.; Grunwald Kadow, I. C.

10.1101/2024.08.07.606811 — neuroscience — Posted on 2024-08-08

3775 Thermally-induced neuronal plasticity that mediates heat tolerance

Siemens, J.; Ambroziak, W.; Nencini, S.; Pohle, J.; Pino, G.; Lundh, S.; Arauja-Sousa, C.; Goetze, L. I. L.; Schrenk-Siemens, K.; Manoj, G.; Herrera, M.; Acuna, C.

10.1101/2024.08.06.606929 — neuroscience — Posted on 2024-08-08

3776 Stochastic Wiring of Cell Types Enhances Fitness by Generating Phenotypic Variability

Lachi, D.; Huang, A.; Mavor-Parker, A. N.; Ghosh, A.; Zador, A.; Richards, B.

10.1101/2024.08.07.606541 — neuroscience — Posted on 2024-08-08

3777 Neural mechanisms of credit assignment for delayed outcomes during contingent learning

Witkowski, P.; Rondot, L.; Kurth-Nelson, Z.; Garvert, M. M.; Dolan, R. J.; Behrens, T. E.; Boorman, E.

10.1101/2024.08.06.606895 — neuroscience — Posted on 2024-08-08

3778 Therapeutic potential of red blood cell-derived extracellular vesicles in reducing neuroinflammation and protecting against retinal degeneration.

Sekar, R.; Cioanca, A. V.; Yang, Y.; Kamath, K. S.; Carroll, L.; Natoli, R.; Wooff, Y.

10.1101/2024.08.06.606930 — neuroscience — Posted on 2024-08-08

3779 Persistent changes in nociceptor translatomes govern hyperalgesic priming in mouse models

Sankaranarayanan, I.; Kume, M.; Mohammed, A.; Mwirigi, J. M.; Inturi, N. N.; Munro, G.; Petersen, K. A.; Tavares-Ferreira, D.; Price, T. J.

10.1101/2024.08.07.606891 — neuroscience — Posted on 2024-08-08

3780 Evaluation of resistant starch from teff (Eragrostis tef) grain as a film coating material for colon-targeted drug delivery

Teshome, Y. G.-M.; Belete, A. G.-M.; Gebre-Mariam, T.

10.1101/2024.08.06.606940 — pharmacology and toxicology — Posted on 2024-08-08

3781 Extracellular vesicle mobility in collagen I hydrogels is influenced by RGD-binding integrins

Tam, N. W.; Becker, A.; Mangiarotti, A.; Cipitria, A.; Dimova, R.

10.1101/2024.05.29.596426 — biophysics — Posted on 2024-08-08

3782 Loss of multi-level 3D genome organization during breast cancer progression

Rossini, R.; Oshaghi, M.; Nekrasov, M.; Bellanger, A.; Domaschenz, R.; Dijkwel, Y.; Abdelhalim, M.; Collas, P.; Tremethick, D.; Paulsen, J.

10.1101/2023.11.26.568711 — genomics — Posted on 2024-08-08

3783 Waning immunity drives respiratory virus evolution and reinfection

Bull, J. J.; Koelle, K.; Antia, R.

10.1101/2024.07.23.604867 — evolutionary biology — Posted on 2024-08-08

3784 A spatial threshold for astrocyte calcium surge

Lines, J.; Baraibar, A. M.; Nanclares, C.; Martin, E.; Aguilar, J. d. l. R.; Kofuji, P.; Navarrete, M.; Araque, A.

10.1101/2023.07.18.549563 — neuroscience — Posted on 2024-08-08

3785 Unifying regulatory motifs in endocrine circuits

Raz, M.; Glass, D. S.; Milo, T.; Kohanim, Y. K.; karin, O.; Tendler, A.; Mayo, A.; Alon, U.

10.1101/2024.08.06.606903 — systems biology — Posted on 2024-08-08

3786 Engineering synthetic agonists for targeted activation of Notch signaling

Perez, D. H.; Antfolk, D.; Medina, E.; Gonzalez-Perez, D.; Luca, V. C.

10.1101/2024.08.06.606897 — synthetic biology — Posted on 2024-08-08

3787 SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma

Elaimy, A. L.; El-Derany, M. O.; James, J.; Wang, Z.; Pearson, A. N.; Holcomb, E. A.; Huber, A. K.; Gijon, M.; Bell, H. N.; Sanghvi, V. R.; Frankel, T. L.; Su, G. L.; Tapper, E. B.; Tai, A. W.; Ramnath, N.; Centonze, C. P.; Dobrosotskaya, I.; Moeller, J. A.; Bryant, A. K.; Elliott, D. A.; Choi, E.; Evans, J. R.; Cuneo, K. C.; Fitzgerald, T. J.; Wahl, D. R.; Morgan, M. A.; Chang, D. T.; Wicha, M. S.; Lawrence, T. S.; Shah, Y. M.; Green, M. D.

10.1101/2024.08.06.606899 — cancer biology — Posted on 2024-08-08

3788 Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl- Channel

Phan, L. X.; Owji, A. P.; Yang, T.; Crain, J.; Sansom, M.; Tucker, S. J.

10.1101/2023.11.14.567055 — biophysics — Posted on 2024-08-08

3789 Alternative Conformations of lncRNAs Identified Through Structural Deconvolution of SHAPE- and DMS-MaP Datasets

Fallon, L.; Jones, A.

10.1101/2024.08.06.606861 — bioinformatics — Posted on 2024-08-08

3790 Engineered Protein-G variants for plug-and-play applications

Slezak, T.; O'Leary, K. M.; Li, J.; Rohaim, A.; Davydova, E. K.; Kossiakoff, A. A.

10.1101/2024.08.06.606809 — bioengineering — Posted on 2024-08-08

3791 Rapid phenotypic and genotypic change in a laboratory schistosome population

Jutzeler, K. S.; Platt, R. N.; Li, X.; Morales, M.; Diaz, R.; Le Clec'h, W.; Chevalier, F.; Anderson, T. J.

10.1101/2024.08.06.606850 — genomics — Posted on 2024-08-08

3792 Phylogenomic prediction of interaction networks in the presence of gene duplication

Gatts, T. C.; deRoux, C.; Lane, L. E.; Berggren, M.; Rehmann, E. A.; Zak, E.; Bartel, T.; L'Argent, L.; Sloan, D. B.; Forsythe, E. S.

10.1101/2024.08.06.606904 — genomics — Posted on 2024-08-08

3793 Performance of low-threshold, population replacement gene drives in cage populations of the yellow fever mosquito, Aedes aegypti

Speth, Z.; Rehard, D.; Norton, P.; Franz, A. W. E.

10.1101/2024.08.06.606841 — genetics — Posted on 2024-08-08

3794 phyddle: software for phylogenetic model exploration with deep learning

Landis, M. J.; Thompson, A.

10.1101/2024.08.06.606717 — evolutionary biology — Posted on 2024-08-08

3795 Multiple Notch ligands in the synchronization of the segmentation clock

Wappner, M.; Uriu, K.; Oates, A. C.; Morelli, L. G.

10.1101/2024.08.06.606905 — developmental biology — Posted on 2024-08-08

3796 TBK1 and IKKϵ protect target cells from IFNγ-mediated T cell killing via an inflammatory apoptotic mechanism

Sun, N. D.; Carr, A. R.; Erica, K. N.; Chawla, Y.; Zhong, J.; Guttormson, M. C.; Chan, M.; Hsu, M. A.; Dong, H.; Bogunovic, D.; Pandey, A.; Rogers, L. M.; Ting, A. T.

10.1101/2024.08.06.606693 — immunology — Posted on 2024-08-08

3797 Histone demethylase LSD1 regulates lipid homeostasis duringCryptococcus neoformans infection

Lohia, G. K.; Shah, A.; Balaji, K. N.

10.1101/2024.08.06.606889 — immunology — Posted on 2024-08-08

3798 The heme-scavenger, hemopexin, protects against fungal lung injury by mitigating NETosis: an experimental and computational study.

Qu, G.; Ribeiro, H. A. L.; Solomon, A. L.; Vieira, L. S.; Goddard, Y.; Diodati, N. G.; Lazarte, A. V.; Wheeler, M.; Laubenbacher, R.; Mehrad, B.

10.1101/2024.08.06.606866 — immunology — Posted on 2024-08-08

3799 Nervous system-wide analysis of all C. elegans cadherins reveals neuron-specific functions across multiple anatomical scales

Majeed, M.; Liao, C.-P.; Hobert, O.

10.1101/2024.08.06.606874 — neuroscience — Posted on 2024-08-08

3800 Turning microglia neuroprotective: Towards connexin43-specific therapy of Alzheimer's disease

YI, C.; SU, Y.; Verkhratsky, A.; NIU, J.

10.1101/2024.08.06.606883 — neuroscience — Posted on 2024-08-08

3801 Prefrontal Cortex subregions provide distinct visual and behavioral feedback modulation to the Primary Visual Cortex

Ahrlund-Richter, S.; Osako, Y.; Jenks, K. R.; Odom, E.; Huang, H.; Arnold, D. B.; Sur, M.

10.1101/2024.08.06.606894 — neuroscience — Posted on 2024-08-08

3802 Iota oscillations (25-35 Hz) during wake and REM sleep in children and young adults

Snipes, S.

10.1101/2024.08.06.606898 — neuroscience — Posted on 2024-08-08

3803 Microglia determine beta-amyloid plaque burden but are non-essential for downstream pathology

Li, M.; Holt, K.; Ridley, K.; Qiu, J.; Haddow, K.; Vasoya, D.; He, X.; Tulloch, J.; King, D.; Hume, D. A.; Pridans, C.; Dando, O. R.; Spires-Jones, T. L.; Hardingham, G. E.

10.1101/2024.08.06.606795 — neuroscience — Posted on 2024-08-08

3804 Hierarchical optimization of biochemical networks

Viswan, N. A.; Tribut, A.; Gasparyan, M.; Radulescu, O.; Bhalla, U. S.

10.1101/2024.08.06.606818 — systems biology — Posted on 2024-08-08

3805 Predicting plasmodesmata-mediated interface permeability and intercellular diffusion

Liesche, J.; Li, J.; Martens, H. J.; Gao, C.; Subroto, C.; Schulz, A.; Deinum, E.

10.1101/2024.08.06.606906 — plant biology — Posted on 2024-08-08

3806 The Impact of Frailty Syndrome on Skeletal Muscle Histology and the Preventive Effects of Exercise

Ji, F.; Kim, J.-H.

10.1101/2024.08.06.606836 — physiology — Posted on 2024-08-08

3807 Cysteine depletion triggers adipose tissue thermogenesis and weight-loss.

Lee, A.; Orliaguet, L.; Youm, Y.-H.; Maeda, R.; Dlugos, T.; Lei, Y.; Coman, D.; Shchukina, I.; Andhey, P. S.; Smith, S. R.; Ravussin, E.; Stadler, K.; Hyder, F.; Artyomov, M. N.; Sugiura, Y.; Dixit, V. D.

10.1101/2024.08.06.606880 — physiology — Posted on 2024-08-08

3808 Timing anti-PD-L1 checkpoint blockade immunotherapy to enhance tumor irradiation

Lee, S. S.-Y.; Pagacz, J.; Averbek, S.; Scholten, D.; Liu, Y.; Kron, S. J.

10.1101/2024.08.06.606845 — cancer biology — Posted on 2024-08-08

3809 Therapeutic targeting of Syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers

Takeda, M.; Theardy, M. S.; Sorokin, A.; Coker, O.; Kanikarla, P.; Chen, S.; Yang, Z.; Nguyen, P.; Wei, Y.; Yao, J.; Wang, X.; Yan, L.; Jin, Y.; Cai, Y.; Paku, M.; Chen, Z.; Li, K. Z.; Citron, F.; Tomihara, H.; Gao, S.; Deem, A. K.; Zhao, J.; Wang, H.; Hanash, S.; DePinho, R. A.; MAITRA, A.; Draetta, G. F.; Ying, H.; Kopetz, S.; Yao, W.

10.1101/2024.08.06.606865 — cancer biology — Posted on 2024-08-08

3810 Integrin blocking peptide reverses immunosuppression in experimental gliomas and improves anti-PD-1 therapy outcome

Ellert-Miklaszewska, A.; Pilanc-Kudlek, P.; Poleszak, K.; Roura, A.-J.; Cyranowski, S.; Ghosh, M.; Baluszek, S.; Pasierbinska, M.; Gielniewski, B.; Swatler, J.; Hovorova, Y.; Wojnicki, K.; Kaminska, B.

10.1101/2024.08.06.606798 — cancer biology — Posted on 2024-08-08

3811 Heat flows solubilize apatite to boost phosphate availability for prebiotic chemistry

Matreux, T.; Schmid, A.; Rappold, M.; Weller, D.; Caliskanoglu, A. Z.; Moore, K. R.; Bosak, T.; Dingwell, D. B.; Karaghiosoff, K.; Guyot, F.; Scheu, B.; Braun, D.; Mast, C. B.

10.1101/2024.08.06.606769 — biophysics — Posted on 2024-08-08

3812 Nano-org, a functional resource for single-molecule localisation microscopy data

Shirgill, S.; Nieves, D. J.; Pike, J. A.; Ahmed, M. A.; Baragilly, M. H. H.; Savoye, K.; Worboys, J.; Hazime, K.; Garcia, A.; Williamson, D. J.; Rubin-Delanchy, P.; Peters, R.; Davis, D. M.; Henriques, R.; Lee, S. F.; Owen, D. M.

10.1101/2024.08.06.606779 — biophysics — Posted on 2024-08-08

3813 Integrative spatiotemporal modeling of biomolecular processes: application to the assembly of the Nuclear Pore Complex

Latham, A. P.; Tempkin, J. O.; Otsuka, S.; Zhang, W.; Ellenberg, J.; Sali, A.

10.1101/2024.08.06.606842 — biophysics — Posted on 2024-08-08

3814 Mixture-of-Experts Approach for Enhanced Drug-Target Interaction Prediction and Confidence Assessment

Lu, Y.; Lee, S.; Kang, S.; Kim, S.

10.1101/2024.08.06.606753 — bioinformatics — Posted on 2024-08-08

3815 Towards Principled Modeling Of Coronary Artery Calcium Scores With Zero-Inflated Regression

Shrikumar, A.; Fathieh, S.; Figtree, G. A.; Grieve, S. M.

10.1101/2024.08.06.606909 — bioinformatics — Posted on 2024-08-08

3816 Elucidating the Hierarchical Nature of Behavior with Masked Autoencoders

Stoffl, L.; Bonnetto, A.; d'Ascoli, S.; Mathis, A.

10.1101/2024.08.06.606796 — animal behavior and cognition — Posted on 2024-08-08

3817 Female Tungara Frogs Discriminate against the Call of Males Infected by Chytridiomycosis

Rodriguez-Brenes, S.; Ryan, M. J.; Garza, S. F.

10.1101/2024.08.06.606873 — animal behavior and cognition — Posted on 2024-08-08

3818 Genomic Loci Associated with Grain Protein and Mineral Nutrients concentrations in Eragrostis tef under Contrasting Water Regimes

Alemu, M. D.; Ben-Zeev, S.; Barak, V.; Tutus, Y.; Cakmak, I.; Saranga, Y.

10.1101/2024.08.06.606859 — genomics — Posted on 2024-08-08

3819 Optics-free reconstruction of 2D images via DNA barcode proximity graphs

Liao, H.; Kottapalli, S.; Huang, Y.; Chaw, M.; Gehring, J.; Waltner, O.; Phung-Rojas, M.; Daza, R. M.; Matsen, F. A.; Trapnell, C.; Shendure, J.; Srivatsan, S. R.

10.1101/2024.08.06.606834 — genomics — Posted on 2024-08-08

3820 VC2 regulates baseline vicine content in faba bean

Ugwuanyi, S.; Makhoul, M.; Golicz, A.; Obermeier, C.; Snowdon, R.

10.1101/2024.08.06.606773 — genetics — Posted on 2024-08-08

3821 High-Resolution Genome Assembly and Population Genetic Study of the Endangered Maple Acer pentaphyllum (Sapindaceae): Implications for Conservation Strategies

Li, X.; Jiang, L.-S.; Deng, H.-N.; Yu, Q.; Ju, W.-B.; Feng, Y.; Xu, B.

10.1101/2024.08.06.606808 — genetics — Posted on 2024-08-08

3822 Genomic data reveal a north-south split and introgression history of blood fluke (Schistosoma haematobium) populations from across Africa

Platt, R. N.; Enabulele, E. E.; Adeyemi, E.; Agbugui, M. O.; Ajakaye, O. G.; Amaechi, E. C.; Ejikeugwu, C. E.; Igbeneghu, C.; Njom, V. S.; Dlamini, P.; Arya, G. A.; Diaz, R.; Rabone, M.; Allan, F.; Webster, B.; Emery, A.; Rollinson, D.; Anderson, T. J.

10.1101/2024.08.06.606828 — evolutionary biology — Posted on 2024-08-08

3823 Single-egg Comet Assay: a protocol to quantify DNA damage in aquatic dormant stages

Salimraj, R.; Perotti, A.; Wojewodzic, M.; Frisch, D.

10.1101/2024.08.06.606806 — ecology — Posted on 2024-08-08

3824 Challenges and lessons learned from preliminary modeling of with-in herd transmission of highly pathogenic avian influenza H5N1 in dairy cattle

Bellotti, B. R.; DeWitt, M. E.; Wenner, J. J.; Lombard, J. E.; McCluskey, B. J.; Kortessis, N.

10.1101/2024.08.06.606397 — ecology — Posted on 2024-08-08

3825 Modeling the effects of vaccination against multiple strains of porcine reproductive and respiratory syndrome at the barn level

Kennedy, F.; Cardenas, N.; Galvis, J. A.; Corzo, C.; Machado, G.

10.1101/2024.08.06.606602 — ecology — Posted on 2024-08-08

3826 p-IgGen: A Paired Antibody Generative Language Model

Turnbull, O. M.; Oglic, D.; Croasdale-Wood, R.; Deane, C. M.

10.1101/2024.08.06.606780 — immunology — Posted on 2024-08-08

3827 Microglia initially seed and later reshape amyloid plaques in Alzheimer's disease

Baligacs, N.; Albertini, G.; Borrie, S. C.; Serneels, L.; Pridans, C.; Balusu, S.; De Strooper, B.

10.1101/2024.08.06.606783 — neuroscience — Posted on 2024-08-08

3828 Repeated activation of preoptic area-recipient neurons in posterior paraventricular nucleus mediates chronic heat-induced negative emotional and hyperarousal states

Cao, Z.; Yung, W.-H.; Ke, Y.

10.1101/2024.08.06.606775 — neuroscience — Posted on 2024-08-08

3829 Sertad1 is elevated and plays a necessary role in synaptic loss, neuron death and cognitive impairment in a model of Alzheimer's disease

Ambareen, N.; Gharami, K.; Biswas, S. C.

10.1101/2024.08.06.606751 — neuroscience — Posted on 2024-08-08

3830 Touch inhibits cold: non-contact cooling reveals a novel thermotactile gating mechanism

Ezquerra-Romano, I.; Chowdhury, M.; Haggard, P.

10.1101/2024.08.06.606653 — neuroscience — Posted on 2024-08-08

3831 Somatosensory stimulation in moving mice

Parkes, I.; Schorscher-Petcu, A.; Gan, Q.; Browne, L. E.

10.1101/2024.08.06.606618 — neuroscience — Posted on 2024-08-08

3832 Micro to macro scale anatomical analysis of the human hippocampal arteries with synchrotron Hierarchical Phase-Contrast Tomography

Bellier, A.; Tafforeau, P.; Bouziane, A.; Angelloz Nicoud, T.; Lee, P. D.; Walsh, C.

10.1101/2024.08.06.605570 — neuroscience — Posted on 2024-08-08

3833 Neural basis of concurrent deliberation toward a choice and degree of confidence

Vivar-Lazo, M.; Fetsch, C. R.

10.1101/2024.08.06.606833 — neuroscience — Posted on 2024-08-08

3834 Differential Contributions of CA3 and Entorhinal Cortex Inputs to Ripple Patterns in the Hippocampus Under Cannabidiol

Aleman-Zapata, A.; Capitan, M. B. M.; Samanta, A.; Ozsezer, P.; Agarwal, K.; Adam, T.; Rayan, A.; Genzel, L.

10.1101/2024.08.06.606645 — neuroscience — Posted on 2024-08-08

3835 Diminished social memory and hippocampal correlates of social interactions in chronic social defeat stress susceptibility

Larosa, A.; Zhang, T. R.; Wong, A. S.; Fung, C. Y. H.; Long, X. L. Y.; Fung, B. C. M.; Wong, T. P.

10.1101/2024.08.06.606823 — neuroscience — Posted on 2024-08-08

3836 Predicting chemotherapy-induced thrombotoxicity by NARX neural networks and transfer learning

Steinacker, M.; Kheifetz, Y.; Scholz, M.

10.1101/2024.08.06.606816 — systems biology — Posted on 2024-08-08

3837 Variability of 7K and 11K SomaScan plasma proteomics assays

Candia, J.; Fantoni, G.; Delgado-Peraza, F.; Shehadeh, N.; Tanaka, T.; Moaddel, R.; Walker, K. A.; Ferrucci, L.

10.1101/2024.08.06.606813 — systems biology — Posted on 2024-08-08

3838 Diabetic liver-enriched secretory dipeptidyl peptidase 4 (DPP4) fuels gut inflammation via attenuation of autophagy

Athar, M.; Bhadury, R.; Gogoi, C.; Mishra, P.; Kumari, P.; Yadav, M.; Maras, J. S.; Ghorpade, D. S.

10.1101/2024.08.06.606776 — physiology — Posted on 2024-08-08

3839 Loss of PRICKLE1 leads to abnormal endometrial epithelial architecture, decreased embryo implantation, and reduced fertility in mice.

Roberts, E.; Bhurke, A. V.; Ganeshkumar, S.; Gunewardena, S.; Arora, R.; Chennathukuzhi, V. M.

10.1101/2024.08.06.605120 — physiology — Posted on 2024-08-08

3840 PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis

Sisson, T. H.; Osterholzer, J. J.; Leung, L.; Basrur, V.; Nesvizhskii, A.; Subbotina, N.; Warnock, M.; Torrente, D.; Virk, A. Q.; Horowitz, J. C.; Migliorini, M.; Strickland, D. K.; Kim, K. K.; Huang, S. K.; Lawrence, D. A.

10.1101/2024.08.06.606812 — pathology — Posted on 2024-08-08

3841 Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation

Elkholi, I. E.; Robert, A.; Malouf, C.; Kuasne, H.; Drapela, S.; Macleod, G.; Hebert, S.; Pacis, A.; Calderon, V.; Kleinman, C. L.; Gomes, A. P.; Aguirre-Ghiso, J. A.; Park, M.; Angers, S.; Cote, J.-F.

10.1101/2023.08.02.551681 — cancer biology — Posted on 2024-08-08

3842 Deciphering tumour microenvironment and elucidating the origin of cancer cells in ovarian clear cell carcinoma

Kamaraj, U. S.; Gautam, P.; Cheng, T.; Chin, T. S.; Tay, S. K.; Ho, T. H.; Nadarajah, R.; Goh, R. C. H.; Wong, S. L.; Mantoo, S.; Busmanis, I.; Li, H.; Le, M. T.; Li, Q.-J.; Lim, E. H.; Loh, Y.-H.

10.1101/2024.08.06.606821 — cancer biology — Posted on 2024-08-08

3843 Controlling DNA-RNA strand displacement kinetics with base distribution

Ratajczyk, E. J.; Bath, J.; Sulc, P.; Doye, J. P. K.; Louis, A. A.; Turberfield, A. J.

10.1101/2024.08.06.606789 — biophysics — Posted on 2024-08-08

3844 Hybrid Protocells based on Coacervate-Templated Fatty Acid Vesicles combine Improved Membrane Stability with Functional Interior Protocytoplasm

Lee, J.; Cakmak, F. P.; Booth, R.; Keating, C. D.

10.1101/2024.08.06.606659 — biophysics — Posted on 2024-08-08

3845 Processivity of the monomeric KLP-6 kinesin and a Brownian ratchet model with symmetric potentials

Kita, T.; Sasaki, K.; Niwa, S.

10.1101/2024.08.06.606760 — biophysics — Posted on 2024-08-08

3846 Context-Aware Hierarchical Fusion for Drug Relational Learning

Lu, Y.; Piao, Y.; Lee, S.; Kim, S.

10.1101/2024.08.06.606750 — bioinformatics — Posted on 2024-08-08

3847 RiboSnake - a user-friendly, robust, reproducible, multipurpose and documentation-extensive pipeline for 16S rRNA gene microbiome analysis

Doerr, A.-K.; Welling, J.; Doerr, A.; Gosch, J.; Moehlen, H.; Schmithausen, R.; Kehrmann, J.; Meyer, F.; Kraiselburd, I.

10.1101/2024.08.06.606757 — bioinformatics — Posted on 2024-08-08

3848 Identifying crosstalks among post-translational modifications in lung cancer proteomic data

Lai, S.; DAI, S.; Zhao, P.; Zhou, C.; Li, N.; Yu, W.

10.1101/2024.08.06.606765 — bioinformatics — Posted on 2024-08-08

3849 Machine learning, molecular docking and simulation studies reveal Lomitapide, Lodipamide, Zafirlukast, Netupitant and Salmon Calcitonin as potent drug molecules against Chagas disease

Singh, K.

10.1101/2024.08.06.606752 — bioinformatics — Posted on 2024-08-08

3850 Predicting mutation-disease associations through protein interactions via deep learning

Li, X.; Cao, B.; Wang, J.; Meng, X.; Wang, S.; Huang, Y.; Petretto, E.; Song, T.

10.1101/2024.08.06.606730 — bioinformatics — Posted on 2024-08-08

3851 Local Mean Gradient Pattern (LMGP): A novel approach made for the classification of brain CT scan images

Singh, K.

10.1101/2024.08.06.606747 — bioengineering — Posted on 2024-08-08

3852 Optics-free Spatial Genomics for Mapping Mouse Brain Aging

Abdulraouf, A.; Jiang, W.; Xu, Z.; Zhang, Z.; Isakov, S.; Raihan, T.; Zhou, W.; Cao, J.

10.1101/2024.08.06.606712 — genomics — Posted on 2024-08-08

3853 Falsifying computational models of angiogenesis through quantitative comparison with in vitro models

Vergroesen, T. M.; Vermeulen, V.; Merks, R. M. H.

10.1101/2024.08.06.606790 — developmental biology — Posted on 2024-08-08

3854 Single-nucleus transcriptomics resolves differentiation dynamics between shoot stem cells and primary stem.

Moreno, S. R.; Lenz, M. O.; Meyerowitz, E. M.; Locke, J. C.; Jonsson, H.

10.1101/2024.08.06.606781 — developmental biology — Posted on 2024-08-08

3855 Maternal sucrose consumption alters steroid levels in the mother, placenta, and fetus

Seib, D. R.; Jung, M. M.; Soma, K. K.

10.1101/2023.10.31.565065 — neuroscience — Posted on 2024-08-08

3856 Repetitive sensory stimulation potentiates and recruits sensory-evoked cortical population activity

Williams, L. E.; Kuffer, L.; Bawa, T.; Husi, E.; Pages, S.; Holtmaat, A.

10.1101/2024.08.06.605968 — neuroscience — Posted on 2024-08-08

3857 Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

Gomez-Frittelli, J.; Devienne, G. F.; Travis, L.; Kyloh, M. A.; Duan, X.; Hibberd, T. J.; Spencer, N. J.; Huguenard, J. R.; Kaltschmidt, J.

10.1101/2024.08.06.606748 — neuroscience — Posted on 2024-08-08

3858 Magnetoelectric Microrobots for Spinal Cord Injury Regeneration

Ye, H.; Zang, J.; Zhu, J.; Arx, D. v.; Pustovalov, V.; Mao, M.; Tang, Q.; Veciana, A.; Torlakcik, H.; Zhang, E.; Sevim, S.; Sanchis-Gual, R.; Chen, X.-Z.; Ahmed, D.; Sanchez-Vives, M. V.; Puigmarti-Luis, J.; Nelson, B. J.; Neuhauss, S. C. F.; Pane, S.

10.1101/2024.08.06.606378 — neuroscience — Posted on 2024-08-08

3859 Local lateral connectivity is sufficient for replicating cortex-like topographical organization in deep neural networks

Qian, X.; Dehghani, A. O.; Farahani, A.; Bashivan, P.

10.1101/2024.08.06.606687 — neuroscience — Posted on 2024-08-08

3860 Infants and adults neurally represent the perspective of others like their own perception

Tebbe, A.-L.; Rothmaler, K.; Koester, M.; Grosse Wiesmann, C.

10.1101/2024.08.06.605501 — neuroscience — Posted on 2024-08-08

3861 Dose, temperature and formulation shape Metarhizium anisopliae virulence against the oriental fruit fly: lessons for improving on-target control strategies

Chailleux, A.; Coulibaly, O. N.; Diouf, B.; Diop, S.; Sohel, A.; Brevault, T.

10.1101/2023.12.14.571642 — zoology — Posted on 2024-08-08

3862 Defining the cardiac fibroblast secretome in the healthy and infarcted mouse heart

Bahr, J.; Poschmann, G.; Jungmann, A.; Busch, M.; Ding, Z.; Zalfen, R.; Steinhausen, J.; Wachtmeister, T.; Rickert, D.; Lautwein, T.; Alter, C.; Amrute, J. M.; Lavine, K. J.; Koehrer, K.; Most, P.; Stuehler, K.; Hesse, J.; Schrader, J.

10.1101/2024.08.06.606146 — physiology — Posted on 2024-08-08

3863 Sex-chromosome-dependent aging in female heterogametic methylomes

Tangili, M.; Sudyka, J.; Furni, F.; Palsboll, P. J.; Verhulst, S.

10.1101/2024.07.31.605993 — evolutionary biology — Posted on 2024-08-08

3864 Metabolic Reprogramming Driven by Ant2 -Targeting Augments T-Cell Function and Anti-Tumor Immunity

Yosef, O.; Cohen-Daniel, L.; Shamriz, O.; Bar-On, Z.; Saragovi, A.; Abramovich, I.; Agranovich, B.; Lutz, V.; Tam, J.; Permyakova, A.; Gottlieb, E.; Huber, M.; Berger, M.

10.1101/2024.04.21.590436 — immunology — Posted on 2024-08-08

3865 Pre-saccadic enhancement of target stimulus motion influences post-saccadic smooth eye movements

Coop, S. H.; Crutcher, G. W.; Abrham, Y. T.; Bucklaew, A.; Mitchell, J. F.

10.1101/2022.10.10.511640 — neuroscience — Posted on 2024-08-08

3866 Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks

Sui, X.; Lo, J. A.; Luo, S.; He, Y.; Tang, Z.; Lin, Z.; Zhou, Y.; Wang, W. X.; Liu, J.; Wang, X.

10.1101/2024.08.05.606553 — genomics — Posted on 2024-08-08

3867 The novel ECM protein SNED1 mediates cell adhesion via α5β1 integrin

Pally, D.; Kapoor, N.; Naba, A.

10.1101/2024.08.07.606706 — cell biology — Posted on 2024-08-08

3868 Paraptosome: A Novel Pathological Feature in Paraptotic Cell Death

Cui, X.; Zheng, H.; Li, H.; Zhang, F.; Yang, L.; Ni, J.; Wang, D.; Zhang, H.; Tang, P.; Li, R.; Zhang, Q.; Cui, M.

10.1101/2024.08.07.606501 — cell biology — Posted on 2024-08-08

3869 SKAP binding to microtubules reduces friction at the kinetochore-microtubule interface and increases attachment stability under force

Rosas Salvans, M.; Rux, C.; Das, M.; Dumont, S.

10.1101/2024.08.08.607154 — cell biology — Posted on 2024-08-08

3870 Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase

Roas, S. C.; Yagita, Y.; Murphy, P.; Kurzbauer, R.; Clausen, T.; Zavodszky, E.; Hegde, R. S.

10.1101/2024.08.07.607117 — cell biology — Posted on 2024-08-08

3871 ER-phagy drives age-onset remodeling of endoplasmic reticulum structure-function and lifespan

Donahue, E. K.; Hepowit, N. L.; Keuchel, B.; Mulligan, A. G.; Johnson, D. J.; Ellisman, M.; Arrojo e Drigo, R.; MacGurn, J. A.; Burkewitz, K.

10.1101/2024.08.07.607085 — cell biology — Posted on 2024-08-08

3872 Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana

Charura, N.; Llamas, E.; De Quattro, C.; Vilchez, D.; Nowack, M. K.; Zuccaro, A.

10.1101/2023.02.03.526420 — plant biology — Posted on 2024-08-08

3873 Context-dependent effects of CDKN2A and other 9p21 gene losses during the evolution of oesophageal cancer

Ganguli, P.; Colomina-Basanta, C.; Acha-Sagrado, A.; Misetic, H.; Armero-Pineiro, M.; Mendez, A.; Zahra, A.; Devonshire, G.; Kelly, G.; Freeman, A.; Green, M.; Nye, E.; Bichisecchi, A.; Bonfanti, P.; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, ; Rodriguez-Justo, M.; Spencer, J.; Fitzgerald, R. C.; Ciccarelli, F. D.

10.1101/2024.01.24.576991 — cancer biology — Posted on 2024-08-08

3874 Spontaneous and Induced Oscillations in Confined Epithelia

Parmar, T.; Dow, L.; Pruitt, B.; Marchetti, M. C.

10.1101/2024.08.07.607093 — biophysics — Posted on 2024-08-08

3875 Performance and Robustness of Parameter Estimation from Phylogenetic Trees Using Neural Networks

Qin, T.; van Benthem, K.; Valente, L.; Etienne, R.

10.1101/2024.08.02.606350 — evolutionary biology — Posted on 2024-08-08

3876 C-COMPASS: A Neural Network Tool for Multi-Omic Classification of Cell Compartments

Haas, D. T.; Trautmann, E. M.; Mao, X.; Gerl, M.; Klose, C.; Cheng, X.; Hasenauer, J.; Krahmer, N.

10.1101/2024.08.05.606647 — cell biology — Posted on 2024-08-08

3877 SNARE mimicry by the CD225 domain of IFITM3 enables regulation of homotypic late endosome fusion

Rahman, K.; Wilt, I.; Jolley, A. A.; Chowdhury, B.; Datta, S. A.; Compton, A. A.

10.1101/2024.08.07.607021 — cell biology — Posted on 2024-08-08

3878 The synaptonemal complex assembles between meiotic chromosomes by wetting

Gordon, S.; Lee, C. F.; Rog, O.

10.1101/2024.08.07.607092 — cell biology — Posted on 2024-08-08

3879 The two key substitutions in the chromophore environment of mKate2 to produce an enhanced FusionRed-like red fluorescent protein

Ruchkin, D. A.; Gavrikov, A. S.; Kolesov, D. V.; Gorokhovatsky, A. Y.; Chepurnykh, T. V.; Mishin, A. S.; Maximov, E. G.; Pletneva, N. V.; Pletnev, V. Z.; Pavlova, A. M.; Nikitin, V. A.; Lukyanov, K. A.; Bogdanov, A. M.

10.1101/2023.12.05.570295 — molecular biology — Posted on 2024-08-08

3880 Lipopeptide antibiotics disrupt interactions of undecaprenyl phosphate with UptA

Oluwole, A. O.; Kalmankar, N.; Guida, M.; Bennett, J. L.; Poce, G.; Bolla, J. R.; Robinson, C. V.

10.1101/2024.04.02.587717 — molecular biology — Posted on 2024-08-08

3881 SUMO4 promotes SUMO deconjugation required for DNA double-strand break repair.

Garvin, A. J.; Lanz, A.; MacKintosh, M.; Starowicz, K.; Ronson, G.; Walker, A.; Aghabi, Y.; MacKay, H.; Densham, R. R.; Leney, A.; Morris, J. R.

10.1101/2022.03.23.485504 — molecular biology — Posted on 2024-08-08

3882 Cell-free chromatin particles from dying cells promote the induction of an immune response in human lymphocytes

Shabrish, S.; Raghuram, G. V.; Raphael, N.; Narayanan, R.; Lopes, R.; Kondhalkar, D.; Khare, N. K.; Mittra, I.

10.1101/2023.08.07.551233 — immunology — Posted on 2024-08-08

3883 A neurometabolic mechanism involving dmPFC/dACC lactate in physical effort-based decision-making

Clairis, N.; Barakat, A.; Brochard, J.; Xin, L.; Sandi, C.

10.1101/2024.05.02.592220 — neuroscience — Posted on 2024-08-08

3884 Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure

He, T.; Gong, X.; Wang, Q.; Zhu, X.; Liu, Y.; Fang, F.

10.1101/2023.09.07.556631 — neuroscience — Posted on 2024-08-08

3885 Attenuated processing of vowels in the left hemisphere predicts speech-in-noise perception deficit in children with autism

Fadeev, K. A.; Romero Reyes, I. V.; Goiaeva, D. E.; Obukhova, T. S.; Ovsiannikova, T. M.; Prokofyev, A. O.; Rytikova, A. M.; Novikov, A. Y.; Kozunov, V. V.; Stroganova, T. A.; Orekhova, E. V.

10.1101/2024.06.24.600191 — neuroscience — Posted on 2024-08-08

3886 Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategies

Cui, A.; Patel, R.; Bosco, P.; Ackcan, U.; Richters, E.; Barrilero Delgado, P.; Agalliu, D.; Sproul, A. A.

10.1101/2024.04.03.588012 — neuroscience — Posted on 2024-08-08

3887 Extracellular vesicles from microglial cells activated by abnormal heparan sulfate oligosaccharides from Sanfilippo patients impair neuronal dendritic arborization

Dias, C.; Ballout, N.; Morla, G.; Alileche, K.; Santiago, C.; Guerrera, C. I.; Chaubet, A.; Ausseil, J.; Trudel, S.

10.1101/2024.05.22.595318 — neuroscience — Posted on 2024-08-08

3888 Theta transcranial alternating current stimulation is not effective in improving working memory performance

Kasanov, D.; Dorogina, O.; Mushtaq, F.; Pavlov, Y. G.

10.1101/2024.03.20.585954 — neuroscience — Posted on 2024-08-08

3889 PbrSYP71 regulates pollen tube growth by maintaining uneven distribution of the ER in Pyrus

Zhang, M.; Tang, C.; Lan, C.; Zhang, N.; Yue, D.; Xie, Z.; Qian, M.; sun, m.; liu, z.; xie, z.; Zhang, H.; Liu, Z.; Zhang, S.; Wang, P.; Wu, J.

10.1101/2024.01.17.576111 — plant biology — Posted on 2024-08-08

3890 Deep Visual Proteomics reveals DNA replication stress as a hallmark of Signet Ring Cell Carcinoma

Kabatnik, S.; Zheng, X.; Pappas, G.; Steigerwald, S.; Padula, M. P.; Mann, M.

10.1101/2024.08.07.606985 — cancer biology — Posted on 2024-08-08

3891 A computational model of fractal interface formation in bacterial biofilms

Brooks, C.; Yao, M.; McCool, J. T.; Gillman, A.; Suel, G. M.; Mugler, A.; Larkin, J. W.

10.1101/2022.05.10.491419 — biophysics — Posted on 2024-08-08

3892 Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs

Jochheim, A.; Jochheim, F. E.; Kolodyazhnaya, A.; Morice, E.; Steinegger, M.; Soeding, J.

10.1101/2024.03.29.587318 — bioinformatics — Posted on 2024-08-08

3893 Genetic estimates and genome-wide association studies of antibody response in Tanzanian dairy cattle

Hernandez-Castro, L. E.; Cook, E. A. J.; Matika, O.; Mengele, I. J.; Motto, S. K.; Bwatota, S. F.; Zirra-Shallangwa, B.; Pong-Wong, R.; Prendergast, J.; Mrode, R.; Toye, P. G.; Komwihangilo, D. M.; Lyatuu, E.; Karani, B. E.; Nangekhe, G.; Mwai, O. A.; Shirima, G. M.; Bronsvoort, B. M. d. C.

10.1101/2024.08.05.606566 — genetics — Posted on 2024-08-08

3894 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.

10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-08

3895 Microdissected tumor cuboids: a microscale cancer model for large-scale testing that retains a complex tumor microenvironment

Horowitz, L. F.; Rodriguez-Mias, R. A.; Chang, M.; Zhu, S.; Gottshall, N. R.; Stepanov, I.; Stiles, C.; Yeung, M.; Nguyen, T. N.; Lockhart, E. J.; Yeung, R. S.; Villen, J.; Gujral, T. S.; Folch, A.

10.1101/2024.03.22.586189 — cancer biology — Posted on 2024-08-08

3896 Applying gradient tree boosting to QTL mapping with Shapley additive explanations

Ishibashi, T.; Onogi, A.

10.1101/2024.01.15.575690 — genetics — Posted on 2024-08-08

3897 Canonical and non-canonical PRC1 differentially contribute to the regulation of neural stem cell fate

Hoffmann, J.; Schutze, T. M.; Kolodziejczyk, A.; Krankel, A.; Reinhardt, S.; Derihaci, R. P.; Birdir, C.; Wimberger, P.; Koseki, H.; Albert, M.

10.1101/2024.08.07.606990 — developmental biology — Posted on 2024-08-07

3898 Generating Synthetic Task-based Brain Fingerprints for Population Neuroscience Using Deep Learning

Serin, E.; Ritter, K.; Schumann, G.; Banaschewski, T.; Marquand, A.; Walter, H.

10.1101/2024.08.03.606469 — neuroscience — Posted on 2024-08-08

3899 A multiscale functional map of somatic mutations in cancer integrating protein structure and network topology

Zhang, Y.; Leung, A. K.; Kang, J. J.; Sun, Y.; Wu, G.; Li, L.; Sun, J.; Cheng, L.; Qiu, T.; Zhang, J.; Wierbowski, S.; Gupta, S.; Booth, J.; Yu, H.

10.1101/2023.03.06.531441 — systems biology — Posted on 2024-08-08

3900 Repetition effects reveal the sub-sequence representation of actions

Shahbazi, M.; Pruszynski, J. A.; Diedrichsen, J.

10.1101/2024.08.07.607016 — neuroscience — Posted on 2024-08-07

3901 Selective deletion of Tsc1 from mouse cerebellar Purkinje neurons drives sex-specific behavioral impairments linked to autism

Lawson, R. J.; Lipovsek, N. J.; Brown, S. P.; Jena, A. K.; Osko, J. J.; Ransdell, J. L.

10.1101/2024.08.07.607071 — neuroscience — Posted on 2024-08-07

3902 Cell wall composition in relation to photosynthesis across land plants' phylogeny: crops as outliers

Roig-Oliver, M.; Flexas, J.; Clemente-Moreno, M. J.; Carriqui, M.

10.1101/2024.08.07.606640 — plant biology — Posted on 2024-08-07

3903 Emerin deficiency drives MCF7 cells to an invasive phenotype

Hansen, E.; Rolling, C.; Wang, M.; Holaska, J. M.

10.1101/2024.02.21.581379 — cancer biology — Posted on 2024-08-07

3904 Targeting oncogenic K-Ras mutants with a small-molecule degrader through Nedd4-1

Zeng, T.; Jiang, T.; Zhang, B.; Zhang, T.; Dai, W.; Yin, X.; Li, Y.; Wu, C.; Wu, Y.; Chi, X.; Deng, X.; Wang, H.-R.

10.1101/2024.04.26.591418 — cancer biology — Posted on 2024-08-07

3905 A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia

Chakraborty, S.; Morganti, C.; Rivera Pena, B.; Zhang, H.; Verma, D.; Zaldana, K.; Gitego, N.; Ma, F.; Aluri, S.; Pradhan, K.; Gordon, S.; Mantzaris, I.; Goldfinger, M.; Feldman, E.; Gritsman, K.; Shi, Y.; Hubner, S.; Qiu, Y. H.; Brown, B. D.; Skwarska, A.; Verma, A.; Konopleva, M.; Tabe, Y.; Gavathiotis, E.; Colla, S.; Gollob, J.; Dey, J.; Kornblau, S. M.; Koralov, S. B.; Ito, K.; Shastri, A.

10.1101/2024.08.05.599788 — cancer biology — Posted on 2024-08-07

3906 MUC2 Expression Modulates Immune Infiltration in Colorectal Cancer

Raynaud, C. M.; Jabeen, A.; Ahmed, E. I.; Hubrack, S.; Sanchez, A.; Sherif, S.; A Al-Shaibi, A.; Roelands, J.; Lo, B.; Bedognetti, D.; Hendrickx, W. R. L.

10.1101/2024.08.06.594842 — cancer biology — Posted on 2024-08-07

3907 A computational model of fractal interface formation in bacterial biofilms

Brooks, C.; Yao, M.; McCool, J. T.; Gillman, A.; Suel, G. M.; Mugler, A.; Larkin, J. W.

10.1101/2022.05.10.491419 — biophysics — Posted on 2024-08-07

3908 LitGene: a transformer-based model that uses contrastive learning to integrate textual information into gene representations

Jararweh, A.; Macaulay, O.; Arredondo, D.; Oyebamiji, O.; Hu, Y.; Tafoya, L.; Zhang, Y.; Virupakshappa, K.; Sahu, A.

10.1101/2024.08.07.606674 — bioinformatics — Posted on 2024-08-07

3909 Generation of biobased, biodegradable non-woven straw mats for multiple environmentally friendly uses

Gressel, J.; Hoffmann, S.

10.1101/2024.08.07.596360 — bioengineering — Posted on 2024-08-07

3910 Trioxane-based MS-cleavable Cross-linking Mass Spectrometry for Profiling Multimeric Interactions of Cellular Networks

Yu, C.; Novitsky, E.; Wang, X.; Echeverria, I.; Rychnovsky, S.; Huang, L.

10.1101/2024.08.06.606913 — biochemistry — Posted on 2024-08-07

3911 Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers

Thorlacius, A.; Rulev, M.; Sundberg, O.; Sundborger, A.

10.1101/2024.08.07.606963 — biochemistry — Posted on 2024-08-07

3912 Discovery and Engineering of a New BvCas12a Nuclease for Mammalian Genome Editing and Nucleic Acid Detection

SHEN, X.; HUANG, L.; WANG, D.; LIU, C.; CHEN, K.; LI, B.; QI, C.; ZOU, Y.; XIAO, L.; JIANG, Y.; LAN, H.; ZHENG, Y.

10.1101/2024.08.07.606956 — genomics — Posted on 2024-08-07

3913 50-year fire legacy regulates soil microbial carbon and nutrient cycling responses to new fire

Revillini, D.; Searcy, C. A.; Afkhami, M. E.

10.1101/2024.08.06.606581 — ecology — Posted on 2024-08-07

3914 The Influence of Shoreline Residential Development on Riparian and Littoral Habitats in the Belgrade Lakes of Maine

Bevier, C. R.; Cole, F. R.; Gimond, M.; Rueger, B. F.

10.1101/2024.08.06.606825 — ecology — Posted on 2024-08-07

3915 Ecosystem dynamics in wet heathlands: spatial and temporal effects of environmental drivers on the vegetation

Damgaard, C.

10.1101/2024.08.06.606794 — ecology — Posted on 2024-08-07

3916 Resource-use plasticity governs the causal relationship between traits and community structure in model microbial communities

McGuinness, B.; Weber, S. C.; Guichard, F.

10.1101/2024.08.06.606555 — ecology — Posted on 2024-08-07

3917 Tcf21 as a Founder Transcription Factor in Specifying Foxd1 Cells to the Juxtaglomerular Cell Lineage

Anjum, H.; Smith, J. P.; Martini, A. G.; Yacu, G. S.; Medrano, S.; Gomez, R. A.; Sequeira-Lopez, M. L. S.; Quaggin, S. E.; Finer, G.

10.1101/2024.03.25.586641 — developmental biology — Posted on 2024-08-07

3918 Transform the Information Landscape: Applying Waddington Landscape to Information Theory of Aging and Epigenetic Rejeuvanation

Wu, Y.

10.1101/2024.07.20.604423 — developmental biology — Posted on 2024-08-07

3919 p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Montagner, A.; Loiseau, N.; Guillou, H.

10.1101/2024.01.09.574858 — cell biology — Posted on 2024-08-07

3920 Comparative Proteomic Study of Retinal Ganglion Cells Undergoing Various Types of Cellular Stressors

Starr, C. R.; Mobley, J.; Gorbatyuk, M. S.

10.1101/2023.10.06.561236 — molecular biology — Posted on 2024-08-07

3921 Coevolving Residues Distant from the Ligand Binding Site are Involved in GAF Domain Function

Ahmed, W. S.; Geethakumari, A. M.; Sultana, A.; Tiwari, A.; Altamash, T.; Arshad, N.; Visweswariah, S. S.; Biswas, K. H.

10.1101/2024.08.07.605472 — molecular biology — Posted on 2024-08-07

3922 Rapid Raman spectroscopy-based test for antimicrobial resistance

Mushenkov, V.; Zhigalova, K.; Denisov, P.; Gordeev, A.; Lukyanov, D.; Kukushkin, V.; Priputnevich, T.; Zavyalova, E.

10.1101/2024.08.07.606953 — molecular biology — Posted on 2024-08-07

3923 Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis

Fry, L. G.; Roys, H.; Bowlin, A. K.; Venugopal, G.; Bird, J. T.; Weaver, A.; Byrum, S. D.; Weinkopff, T.

10.1101/2024.08.07.605632 — microbiology — Posted on 2024-08-07

3924 NEDD4-binding protein 1 suppresses HBV replication by degrading HBV RNAs

Kobayashi, N.; Suzuki, S.; Sakamoto, Y.; Suzuki, R.; Mori, K.; Kosugi, Y.; Liang, L.; Saito, T.; Izumi, T.; Noda, K.; Okuzaki, D.; Kanegae, Y.; Hayashi, S.; Tanaka, Y.; Matsuura, Y.; Takeuchi, O.; Tamura, T.; Taketomi, A.; Fukuhara, T.

10.1101/2023.10.06.561254 — microbiology — Posted on 2024-08-07

3925 Enhancement strategies for the microbial protein production of nitrogen-fixing hydrogen-oxidizing bacterial community

Wang, H.

10.1101/2024.08.07.607053 — microbiology — Posted on 2024-08-07

3926 Gut microbiome shifts in chronic systolic heart failure are associated with disease severity and clinical improvement

Mamic, P.; Shi, H.; Zhou, W.; Bararpour, N.; Contrepois, K.; Park, H.; Avina, M.; Rose, S. M. S.-F.; Heidenreich, P. A.; Khush, K. K.; Fowler, M. B.; Tang, W. W.; Sallam, K.; Sonnenburg, J. L.; Huang, K. C.; Snyder, M. P.

10.1101/2024.08.06.606872 — microbiology — Posted on 2024-08-07

3927 A Simplified Method for Comprehensive Capture of the Staphylococcus aureus Proteome

Mustor, E. M.; Wohlfahrt, J.; Guergues, J.; Stevens, S.; Shaw, L. N.

10.1101/2024.08.07.607079 — microbiology — Posted on 2024-08-07

3928 Migration and standing genetic variation in vaginal and rectal yeast populations in recurrent vulvovaginal candidiasis

Adamu Bukari, A.-R.; Kukurudz-Gorowski, R.; de Graaf, A.; Habon, D.; Manyaz, B.; Syvolos, Y.; Sumanarathnea, A.; Poliquin, V.; Gerstein, A. C.

10.1101/2023.07.19.549743 — microbiology — Posted on 2024-08-07

3929 Identifying Causal Relations between Gut Microbiome, Metabolic Dysfunction-Associated Fatty Liver Disease and the Novel Mediators of Blood Metabolites

Yi, X.; Zhu, H.; He, M.; Zhong, L.; Li, M.; Gao, S.

10.1101/2024.08.05.606637 — microbiology — Posted on 2024-08-07

3930 In vitro bio-activity of three potential antagonistic fungi against selected plant pathogens in Ghana

Dwamena, E.; Awuah, R. T.; Aidoo, A. K.; Agbetiameh, D.

10.1101/2024.08.07.606921 — microbiology — Posted on 2024-08-07

3931 Immunological response against bovine viral diarrhoea virus (BVDV) types 1 and 2 after vaccination with DIVENCE (R), measured by ELISA and serum neutralisation on serum and milk samples

Montbrau, C.; Gibert, M.; Taberner, E.; Tapiolas, M.; Teixeira, R.; Prenafeta, A.

10.1101/2024.08.06.606756 — immunology — Posted on 2024-08-07

3932 Pathogenic Th17 cells in ZAP-70 mutant mice share T cell receptor features with Wild-type Tregs

Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.

10.1101/2024.03.01.582868 — immunology — Posted on 2024-08-07

3933 From solo to collaborative: the global increase in neuroscience authors over two decades

Segreti, M.; Paul, A.; Pani, P.; Genovesio, A.; Brunamonti, E.

10.1101/2024.08.05.606580 — neuroscience — Posted on 2024-08-07

3934 Intrinsic dynamics shape responses to external stimulation in the human brain

Nentwich, M.; Bickel, S.; Parra, L. C.

10.1101/2024.08.05.606665 — neuroscience — Posted on 2024-08-07

3935 Resting-State Electroencephalography and Magnetoencephalography in Migraine - A Systematic Review and Meta-Analysis

Zebhauser, P. T.; Heitmann, H.; May, E. S.; Ploner, M.

10.1101/2024.08.02.606283 — neuroscience — Posted on 2024-08-07

3936 Imaging the large-scale and cellular response to focal traumatic brain injury in mouse neocortex

Bibineyshvili, Y.; Vajtay, T. J.; Salsabilian, S.; Fliss, N.; Suvarnakar, A.; Fang, J.; Teng, S.; Alder, J.; Najafizadeh, L.; Margolis, D. J.

10.1101/2024.04.24.590835 — neuroscience — Posted on 2024-08-07

3937 Dynamic organization of visual cortical networks inferred from massive spiking datasets.

Graber, C.; Vlasov, Y.; Schwing, A. G.

10.1101/2023.08.08.552512 — neuroscience — Posted on 2024-08-07

3938 Sound preferences in mice are sex-dependent

Sehrawat, K.; Nelken, I.

10.1101/2024.08.04.606510 — neuroscience — Posted on 2024-08-07

3939 The neurophysiology of healthy and pathological aging: A comprehensive systematic review

Fernandez-Rubio, G.; Vuust, P.; Bonetti, L.; Kringelbach, M. L.

10.1101/2024.08.06.606817 — neuroscience — Posted on 2024-08-07

3940 Enhanced Working Memory Representations for Rare Events

Carrasco, C. D.; Simmons, A. M.; Kiat, J. E.; Luck, S. J.

10.1101/2024.03.20.585952 — neuroscience — Posted on 2024-08-07

3941 A Curated Compendium of Transcriptomic Data for the Exploration of Neocortical Development

Sonthalia, S.; Li, G.; Blanco, X. M.; Casella, A.; Liu, J.; Stein-O'Brien, G.; Caffo, B.; Adkins, S.; Orvis, J.; Hertzano, R.; Mahurkar, A.; Gillis, J. A.; Werner, J.; Ma, S.; Micali, N.; Sestan, N.; Rakic, P.; Baro, G. S.; Ament, S. A.; Colantuoni, C.

10.1101/2024.02.26.581612 — neuroscience — Posted on 2024-08-07

3942 Mitochondrial leakage and mtDNA damage trigger early immune response in Inclusion Body Myositis.

Kleefeld, F.; Cross, E.; Lagos, D.; Schoser, B.; Hentschel, A.; Ruck, T.; Nelke, C. J.; Walli, S.; Hahn, K.; Hathazi, D.; Mammen, A. L.; Casal-Dominguez, M.; Gut, M.; Gut, I.; Heath, S.; Schaenzer, A.; Goebel, H.-H.; Pinal-Fernandez, I.; Roos, A.; Preusse, C.; Stenzel, W.; Horvath, R.

10.1101/2024.08.05.606624 — neuroscience — Posted on 2024-08-07

3943 Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence.

Alonso-Caraballo, Y.; Li, Y.; Constantino, N. J.; Neal, M. A.; Driscoll, G. S.; Mavrikaki, M.; Bolshakov, V. Y.; Chartoff, E. H.

10.1101/2024.08.01.605459 — neuroscience — Posted on 2024-08-07

3944 Shared Neural Dynamics of Facial Expression Processing

Ely, M. M.; Ambrus, G. G.

10.1101/2024.08.05.606517 — scientific communication and education — Posted on 2024-08-07

3945 Sympathetic Motor Neuron Dysfunction is a Missing Link in Age-Associated Sympathetic Overactivity

de la Cruz, L.; Bui, D.; Moreno, C. M.; Vivas, O.

10.1101/2023.09.27.559800 — physiology — Posted on 2024-08-07

3946 Quantifying the Impact of Co-Housing on Murine Aging Studies

Luciano, A.; Churchill, G. A.

10.1101/2024.08.06.606373 — bioinformatics — Posted on 2024-08-07

3947 Zinc and Metformin Co-Functionalized Polyetheretherketone: A Novel Dental Implant Material Tailored for the Elderly

Liu, Z.; Zhao, E.; Huang, H.; Wu, Y.; He, Y.; Bai, S.; Wang, S.; Fan, S.; Cao, S.; Tang, B.; Wang, Y.

10.1101/2024.08.05.606613 — bioengineering — Posted on 2024-08-07

3948 Dynamic regulation of engineered T7 RNA polymerases by endogenous metabolites

Baumer, Z. T.; Newton, M.; Löfstrand, L.; Carpio Paucar, G. N.; Farny, N. G.; Whitehead, T. A.

10.1101/2024.08.07.607023 — bioengineering — Posted on 2024-08-07

3949 VUStruct: a compute pipeline for high throughput and personalized structural biology

Moth, C. W.; Sheehan, J. H.; Mamun, A. A.; Sivley, R. M.; Gulsevin, A.; Rinker, D.; Capra, J. A.; Meiler, J.

10.1101/2024.08.06.606224 — biochemistry — Posted on 2024-08-07

3950 The pseudoenzyme β-amylase9 from Arabidopsis binds to and enhances the activity of α-amylase3: A possible mechanism to promote stress-induced starch degradation

Berndsen, C. E.; Storm, A. R.; Sardelli, A. M.; Hossain, S. R.; Clermont, K. R.; McFather, L. M.; Connor, M. A.; Monroe, J.

10.1101/2024.08.07.607052 — biochemistry — Posted on 2024-08-07

3951 Extensively acquired antimicrobial resistant bacteria restructure the individual microbial community in post-antibiotic conditions

Baek, J. W.; Lim, S.; Park, N.; Song, B.; Kirtipal, N.; Nielsen, J.; Mardinoglu, A.; Shoaie, S.; Kim, J.-i.; Son, J. W.; Koh, A.; Lee, S.

10.1101/2024.08.07.606955 — genomics — Posted on 2024-08-07

3952 Latent generative modeling of long genetic sequences with GANs

Szatkownik, A.; Furtlehner, C.; Charpiat, G.; Yelmen, B.; Jay, F.

10.1101/2024.08.07.607012 — genomics — Posted on 2024-08-07

3953 Transposable elements impact the regulatory landscape through cell type specific epigenomic associations

Hyacinthe, J.; Bourque, G.

10.1101/2024.08.07.606967 — genomics — Posted on 2024-08-07

3954 Improved vectors for retron-mediated CRISPR-Cas9 genome editing in Saccharomyces cerevisiae

Stuecker, T. N.; Hood, S. E.; Molina Pineda, J.; Lenaduwe, S.; Winter, J.; Sadhu, M. J.; Lewis, J. A.

10.1101/2024.08.06.606807 — genetics — Posted on 2024-08-07

3955 Neolithic introgression of IL23R-related protection against chronic inflammatory bowel diseases in modern Europeans

Krause-Kyora, B.; da Silva, N. A.; Kaplan, E.; Kolbe, D.; Wohlers, I.; Busch, H.; Ellinghaus, D.; Caliebe, A.; Sezgin, E.; Nebel, A.; Schreiber, S.

10.1101/2024.08.06.606840 — evolutionary biology — Posted on 2024-08-07

3956 Global invasion patterns and dynamics of disease vector mosquitoes

Pabst, R.; Sousa, C. A.; Essl, F.; Garcia-Rodriguez, A.; Liu, D.; Lenzner, B.; Schertler, A.; Zezere, J. L.; Capinha, C.

10.1101/2024.08.06.606755 — ecology — Posted on 2024-08-07

3957 Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles

Vendrell-Fernandez, S.; Beamud, B.; Abou-Haydar, Y.; Am de Sousa, J.; Burlaud-Gaillard, J.; Kornobis, E.; Raynal, B.; Vinh, J.; Bikard, D.; Ghigo, J.-M.

10.1101/2024.08.07.606950 — microbiology — Posted on 2024-08-07

3958 PneumoBrowse 2: An integrated visual platform for curated genome annotation and multiomics data analysis of Streptococcus pneumoniae

Janssen, A. B.; Gibson, P. S.; Bravo, A. M.; de Bakker, V.; Slager, J.; Veening, J.-W.

10.1101/2024.08.07.606308 — microbiology — Posted on 2024-08-07

3959 AMPK/ULK1 activation downregulates TXNIP, Rab5, and Rab7 and inhibits endocytosis-mediated entry of human pathogenic viruses

Diesendorf, V.; La Rocca, V.; Teutsch, M.; Alattar, H.; Obernolte, H.; Kenst, K.; Seibel, J.; Worsdorfer, P.; Sewald, K.; Steinke, M.; Schneider-Schaulies, S.; Lutz, M. B.; Munschauer, M.; Bodem, J.

10.1101/2024.08.06.606943 — microbiology — Posted on 2024-08-07

3960 Cultivar-specific fungicide resistance emerges during a growing season in field populations of Zymoseptoria tritici

Talas, F.; Stapley, J.; McDonald, B. A.

10.1101/2024.08.07.606886 — microbiology — Posted on 2024-08-07

3961 UFMylation suppresses Type I IFN signaling during M. tuberculosis infection of human macrophages

Garelis, N. E.; Luteijn, R.; Raulet, D.; Cox, J. S.

10.1101/2024.08.07.607094 — microbiology — Posted on 2024-08-07

3962 Decoding critical targets and signaling pathways in EBV-mediated diseases using large language models

Yu, J.; Wang, Y.; Wang, H.; Wei, Z.; Pei, Y.

10.1101/2024.08.06.605212 — microbiology — Posted on 2024-08-07

3963 Molecular Identification and Antimicrobial Potential of Endophytic Fungi Against Some Grapevine Pathogens

Haleem, R. A.; Nashat, L. H.; Ali, S. H.

10.1101/2024.08.06.606939 — microbiology — Posted on 2024-08-07

3964 MMINT: a Metabolic Model Interactive Network Tool for the exploration and comparative visualisation of metabolic networks

Molina Ortiz, J. P.; Morgan, M. M.; Paten, A. M.; Warden, A. C.; Kilby, P.

10.1101/2024.08.06.606923 — synthetic biology — Posted on 2024-08-07

3965 Forest dieback in drinking water protection areas - a hidden threat to water quality

Winter, C.; Mueller, S.; Kattenborn, T.; Stahl, K.; Szillat, K.; Weiler, M.; Schnabel, F.

10.1101/2024.08.07.606951 — biochemistry — Posted on 2024-08-07

3966 Scalable imaging-free spatial genomics through computational reconstruction

Hu, C.; Borji, M.; Marrero, G. J.; Kumar, V.; Weir, J. A.; Kammula, S. V.; Macosko, E. Z.; Chen, F.

10.1101/2024.08.05.606465 — genomics — Posted on 2024-08-07

3967 Evolution of sex hormone-binding globulin gene expression in the primate testis

Meyers, W. M.; Hammond, G. L.

10.1101/2024.08.05.606716 — evolutionary biology — Posted on 2024-08-07

3968 Comparative Analysis of Housing Temperature Impact on Heart Failure with Preserved Ejection Fraction in J vs N Strain C57BL/6 Mice

Chaudhary, R.; Suhan, T. K.; Wu, C.; Alzamrooni, A.; Abdel-Latif, A.

10.1101/2024.08.05.606691 — immunology — Posted on 2024-08-07

3969 Cortical Representation of the Glottal Events during Speech Production

Veillette, J. P.; Rosen, J.; Margoliash, D.; Nusbaum, H. C.

10.1101/2024.08.07.607082 — neuroscience — Posted on 2024-08-07

3970 Predicting purification process fit of monoclonal antibodies using machine learning

Maier, A. J.; Cha, M.; Burgess, S.; Wang, A.; Cuellar, C.; Kim, S.; Rajan, N. S.; Neyyan, J.; Sengupta, R.; O'Connor, K.; Ott, N.; Williams, A. J.

10.1101/2024.08.05.606711 — bioinformatics — Posted on 2024-08-07

3971 Cryptic host phenotypic heterogeneity drives diversification of bacteriophage {lambda}

De La Fuente, C. A.; Lahoud, N.; Meyer, J. R.

10.1101/2024.08.05.606710 — evolutionary biology — Posted on 2024-08-07

3972 Evolutionary rates of nuclear and organellar genomes are linked in land plants

Asar, Y.; Sauquet, H.; Ho, S. Y. W.

10.1101/2024.08.05.606707 — evolutionary biology — Posted on 2024-08-07

3973 Trophic transfer and bioaccumulation of nanoplastics in Coryphaena hippurus (Mahi-mahi) and effect of depuration

Dey, P.; Bradley, T. M.; Boymelgreen, A.

10.1101/2024.08.05.606698 — ecology — Posted on 2024-08-07

3974 Assessing the effects of female protections on size structure and spawning potential in two clawed lobster fisheries subject to varying exploitation levels

Theberge, K.; Sordalen, T. K.; Pugh, T. L.; Kindsvater, H. K.

10.1101/2024.08.05.606679 — ecology — Posted on 2024-08-07

3975 Three-dimensional culture in a bioengineered matrix and somatic cell complementation to improve growth and survival of bovine preantral follicles

Candelaria, J. I.; Botigelli, R. C.; Guiltinan, C.; Shikanov, A.; Denicol, A. C.

10.1101/2024.07.18.604061 — developmental biology — Posted on 2024-08-07

3976 An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells

Warder, B. N.; Nelson, K. A.; Sui, J.; Anllo, L.; DiNardo, S.

10.1101/2023.09.08.556877 — developmental biology — Posted on 2024-08-07

3977 A single-nucleus census of immune and non-immune cell types for the major immune organ systems of chicken.

Sculley, E. R.; Rice, E. S.; Carroll, R. A.; Driver, J. P.; Smith, J.; Kaufman, J.; Hearn, C.; Balic, A.; Chen, P.; Lamont, S. J.; Kramer, S.; Drechsler, Y.; Cheng, H.; Warren, W. C.

10.1101/2024.08.05.606414 — immunology — Posted on 2024-08-07

3978 CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading

Sun, Y.; Pumroy, R. A.; Mallik, L.; Chaudhuri, A.; Wang, C.; Hwang, D.; Danon, J.; Dasteh Goli, K.; Moiseenkova-Bell, V.; Sgourakis, N.

10.1101/2024.08.05.606663 — immunology — Posted on 2024-08-07

3979 Desegregation of neuronal predictive processing

Wang, B.; Audette, N. J.; Schneider, D. M.; Aljadeff, J.

10.1101/2024.08.05.606684 — neuroscience — Posted on 2024-08-07

3980 Cortical areas for planning sequences before and during movement

Ariani, G.; Shahbazi, M.; Diedrichsen, J.

10.1101/2023.11.05.565682 — neuroscience — Posted on 2024-08-07

3981 Spatial sampling of deep neural network features improves encoding models of foveal and peripheral visual processing in humans

Mueller, N.; Scholte, H. S.; Groen, I. I. A.

10.1101/2024.08.05.606515 — neuroscience — Posted on 2024-08-07

3982 Image retrieval based on closed-loop visual-semantic neural decoding

Fukuma, R.; Yanagisawa, T.; Sugano, H.; Tamura, K.; Oshino, S.; Tani, N.; Iimura, Y.; Khoo, H. M.; Suzuki, H.; Yang, H.; Iwata, T.; Nakajima, M.; Nishimoto, S.; Kamitani, Y.; Kishima, H.

10.1101/2024.08.05.606113 — neuroscience — Posted on 2024-08-07

3983 Manipulation of the microRNA172 - AP2L2 interaction provides precise control of wheat and triticale plant height

Zhang, C.; Hegarty, J.; Padilla, M.; Tricoli, D. M.; Dubcovsky, J.; Debernardi, J. M.

10.1101/2024.08.05.606718 — plant biology — Posted on 2024-08-07

3984 Ethanol exposure model in zebrafish causes phenotypic, behavioral and gene expression changes that mimic Fetal Alcohol Spectrum Disorders in human birth cohorts

Yilmaz, E.; Nelson, N.; tosto, g.; Carter, R. C.; Kizil, C.

10.1101/2024.08.05.606708 — pathology — Posted on 2024-08-07

3985 Exploit Spatially Resolved Transcriptomic Data to Infer Cellular Features from Pathology Imaging Data}

Sui, Z.; Li, Z.; Sun, W.

10.1101/2024.08.05.606654 — cancer biology — Posted on 2024-08-07

3986 Role of SCAL1 in Modulating Oxidative Stress, Cancer Stemness, Apoptotic Resistance in Tumorigenic Differentiation of Cigarette Smoke-Exposed BEAS-2B Cells

Sengupta, D.; Banerjee, S.; Sengupta, M.

10.1101/2024.08.05.606632 — cancer biology — Posted on 2024-08-07

3987 Structures of human PTP1B variants reveal allosteric sites to target for weight loss therapy

Perdikari, A.; Woods, V. A.; Ebrahim, A.; Lawler, K.; Bounds, R.; Singh, N. I.; Mehlman, T.; Riley, B. T.; Sharma, S.; Morris, J. W.; Keogh, J. M.; Henning, E.; Smith, M.; Farooqi, I. S.; Keedy, D. A.

10.1101/2024.08.05.603709 — biophysics — Posted on 2024-08-07

3988 LongReadSum: A fast and flexible quality control and signal summarization tool for long-read sequencing data

Perdomo, J. E.; Ahsan, M. U.; Liu, Q.; Fang, L.; Wang, K.

10.1101/2024.08.05.606643 — bioinformatics — Posted on 2024-08-07

3989 PeakClimber: A software tool for analyzing biological HPLC data using the exponential Gaussian function

Derrick, J.; Farber, S. A.; Ludington, W. B.

10.1101/2024.08.05.606689 — bioengineering — Posted on 2024-08-07

3990 In-silico heart model phantom to validate cardiac strain imaging

Mukherjee, T.; Usman, M.; Mehdi, R. R.; Mendiola, E.; Ohayon, J.; Lindquist, D.; Shah, D.; Sadayappan, S.; Pettigrew, R.; Avazmohammadi, R.

10.1101/2024.08.05.606672 — bioengineering — Posted on 2024-08-07

3991 Highly extensible physically crosslinked hydrogels for high-speed 3D bioprinting

Song, Y. E.; Eckman, N.; Sen, S.; Saouaf, O. M.; Appel, E.

10.1101/2024.08.05.606733 — bioengineering — Posted on 2024-08-07

3992 Quadrant darkfield (QDF) for label-free imaging of intracellular puncta

Moustafa, T. E.; Belote, R. L.; Polanco, E. R.; Judson-Torres, R. L.; Zangle, T. A.

10.1101/2024.08.05.606686 — bioengineering — Posted on 2024-08-07

3993 A Dual-Fluorescence Assay for Gene Delivery Vehicle Screening in Macrophages with an Inflammation-Inducible Reporter Construct

Ivy, A.; Bess, S. N.; Agrawal, S.; Kochar, V.; Muldoon, T. J.; Nelson, C. E.

10.1101/2024.08.05.606664 — bioengineering — Posted on 2024-08-07

3994 Temporal and spatial population genetic variation in Chilean jack mackerel, Trachurus murphyi

Canales-Aguirre, C. B.; Ferrada-Fuentes, S.; Galleguillos, R.

10.1101/2024.08.05.606603 — genetics — Posted on 2024-08-07

3995 Using phylogenetic summary statistics for epidemiological inference

Nunez, R. C.; Hart, G. R.; Famulare, M.; Lorton, C.; Herbeck, J. T.

10.1101/2024.08.07.607080 — genetics — Posted on 2024-08-07

3996 Interpretable Solutions for Stochastic Dynamic Programming

Mestres, J. F.; Dietterich, T. G.; Buffet, O.; Chades, I.

10.1101/2024.08.05.606713 — ecology — Posted on 2024-08-07

3997 A transgene-free, human peri-gastrulation embryo model with trilaminar embryonic disc-, amnion- and yolk sac-like structures

Sun, S.; Zheng, Y.; Kim, Y. S.; Zhong, Z.; Kobayashi, N.; Xue, X.; Liu, Y.; Zhou, Z.; Xu, Y.; Zhai, J.; Wang, H.; Fu, J.

10.1101/2024.08.05.606556 — developmental biology — Posted on 2024-08-07

3998 Th1 polarization in Bordetella pertussis vaccine responses is maintained through a positive feedback loop

Willemsen, L.; Lee, J.; Shinde, P.; Soldevila, F.; Aoki, M.; Orfield, S.; Kojima, M.; Antunes, R. d. S.; Sette, A.; Peters, B.

10.1101/2024.08.05.606623 — immunology — Posted on 2024-08-07

3999 Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

Yu, H.; Nishio, H.; Barbi, J.; Mitchell-Flack, M.; Vignali, P. D. A.; Zheng, Y.; Lebid, A.; Chang, K.-Y.; Fu, J.; Higgins, M.; Huang, C.-T.; Zhang, X.; Li, Z.; Blosser, L.; Tam, A.; Drake, C. G.; Pardoll, D. M.

10.1101/2024.01.31.578284 — immunology — Posted on 2024-08-07

4000 Arsenic impairs Drosophila neural stem cell mitotic progression and sleep behavior in a tauopathy model

Adebambo, T. H.; Flores, M. F. M.; Zhang, S. L.; Lerit, D.

10.1101/2024.08.05.606375 — neuroscience — Posted on 2024-08-07

4001 Brief encounters with real objects modulate medial parietal but not occipitotemporal cortex

Wardle, S.; Rispoli, B.; Roopchansingh, V.; Baker, C.

10.1101/2024.08.05.606667 — neuroscience — Posted on 2024-08-07

4002 Slow-wave sleep and REM sleep differentially contribute to memory representational transformation

Liu, J.; Chen, D.; Xia, T.; Zeng, S.; Xue, G.; Hu, X.

10.1101/2024.08.05.606592 — neuroscience — Posted on 2024-08-07

4003 From Maps to Models: A Survey on the Reliability of Small Studies of Task-Based fMRI

Sadil, P.; Lindquist, M. A.

10.1101/2024.08.05.606611 — neuroscience — Posted on 2024-08-07

4004 Transcranial focused ultrasound modulates visual thalamus in a nonhuman primate model

Yu, K.; He, B.

10.1101/2024.08.05.606669 — neuroscience — Posted on 2024-08-07

4005 Formation of an Enduring Ensemble of Accumbens Neurons Leads to Prepotent Seeking for Cocaine Over Natural Reward Cues

Chalhoub, R. M.; Testen, A.; Hopkins, J.; Carthy, C.; Kalivas, P. W.

10.1101/2024.08.05.606522 — neuroscience — Posted on 2024-08-07

4006 Parcellation of the primate prefrontal cortex by cognitive control operations

Wang, X.; Hähnke, D.; Nieder, A.; Jacob, S. N.

10.1101/2024.08.05.606700 — neuroscience — Posted on 2024-08-07

4007 Spike-to-excite: photosensitive seizures in biologically-realistic spiking neural networks

Taylor, L.; Fasol, M. C. M.

10.1101/2024.08.05.606699 — neuroscience — Posted on 2024-08-07

4008 Specific light-regime adaptations, terpenoid profiles and engineering potential in ecologically diverse Phaeodactylum tricornutum strains

Morelli, L.; Patwari, P.; Pruckner, F.; Bastide, M.; Fabris, M.

10.1101/2024.08.05.606631 — plant biology — Posted on 2024-08-07

4009 Rare earth elements extraction from Idaho-sourced surface soil by phytomining

Richardson, K.; Mirkouei, A.; Duellman, K.; Aylward, A.; Zirker, D.; Schwarz, E.; Sun, Y.

10.1101/2024.08.05.606409 — plant biology — Posted on 2024-08-07

4010 CqHKT1 and CqSOS1 mediate genotype-dependent Na+ exclusion under high salt stress in quinoa

Kobayashi, Y.; Sugita, R.; Fujita, M.; Yasui, Y.; Murata, Y.; Ogata, T.; Nagatoshi, Y.; Fujita, Y.

10.1101/2024.08.05.606677 — plant biology — Posted on 2024-08-07

4011 Unravelling biological processess and EGFR pathway regulation by the receptor-like protein tyrosine phosphatase PTPRH in non-small cell lung cancer

Ortiz, M. M. O.; Patel, D. M.; Swiatnicki, M.; Andrechek, E. R.

10.1101/2024.06.13.598886 — cancer biology — Posted on 2024-08-07

4012 Chronic cigarette smoke exposure masks pathological features of Helicobacter pylori infection while promoting tumor initiation

Morris, M. T.; Piazuelo, M. B.; Olfert, I. M.; Xu, X.; Hussain, S.; Peek, R. M.; Busada, J. T.

10.1101/2024.08.05.604297 — cancer biology — Posted on 2024-08-07

4013 Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma

Shema, E.; Griess, O.; Furth, N.; Harpaz, N.; Di Bernardo, N.; Salame, T. M.; Dassa, B.; Karagiannidis, I.; Isshiki, Y.; Gross, M.; Melnick, A. M.; Beguelin, W.; Ron, G.

10.1101/2024.08.05.606629 — cancer biology — Posted on 2024-08-07

4014 Gene Expression Prediction from Histology Images via Hypergraph Neural Networks

Li, B.; Zhan, Y.; Wang, Q.; Zhang, C.; Li, M.; Wang, G.; Song, Q.

10.1101/2024.08.05.606608 — bioinformatics — Posted on 2024-08-07

4015 PGSFusion streamlines polygenic score construction and epidemiological applications in biobank-scale cohorts

Yang, S.; Ye, X.; Ji, X.; Li, Z.; Tian, M.; Huang, P.; Cao, C.

10.1101/2024.08.05.606619 — bioinformatics — Posted on 2024-08-07

4016 Ordering molecular diversity in untargeted metabolomics via molecular community networking

Coler, E. A.; Melnik, A.; Lotfi, A.; Moradi, D.; Ahiadu, B.; Portal Gomes, P. W.; Patan, A.; Dorrestein, P. C.; Barnes, S.; Boginski, V.; Semenov, A.; Aksenov, A. A.

10.1101/2024.08.02.606356 — biochemistry — Posted on 2024-08-07

4017 Genome-Wide Association Study and transcriptome analysis reveals a complex gene network that regulates opsin gene expression and cell fate determination in Drosophila R7 photoreceptor cells.

Aldrich, J. C.; Vanderlinden, L. A.; Jacobsen, T. L.; Wood, C.; Saba, L. M.; Britt, S. G.

10.1101/2024.08.05.606616 — genomics — Posted on 2024-08-07

4018 Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocks

Sui, X.; Lo, J. A.; Luo, S.; He, Y.; Tang, Z.; Lin, Z.; Zhou, Y.; Wang, W. X.; Liu, J.; Wang, X.

10.1101/2024.08.05.606553 — genomics — Posted on 2024-08-07

4019 Towards an automated protocol for wildlife density estimation using camera-traps

Zampetti, A.; Mirante, D.; Palencia, P.; Santini, L.

10.1101/2024.08.05.606345 — ecology — Posted on 2024-08-07

4020 Environmental controls on crenarchaeol distributions in hydrothermal springs

Calhoun, A. N.; Blewett, J.; Colman, D.; Amenabar, M. J.; Harris, C. M.; Boyd, E.; Pearson, A.; Leavitt, W. D.

10.1101/2024.07.09.602736 — microbiology — Posted on 2024-08-07

4021 Mast cell-derived chymases are essential for the resolution of inflammatory pain in mice

de Souza, S.; Laumet, S.; Inyang, K. E.; Hua, H.; Sim, J.; Folger, J. K.; Moeser, A. J.; Laumet, G.

10.1101/2024.08.05.606617 — immunology — Posted on 2024-08-07

4022 High-grade serous ovarian cancer development and anti-PD-1 resistance is driven by IRE1α activity in neutrophils

Emmanuelli, A.; Salvagno, C.; Hwang, S.-M.; Awasthi, D.; Sandoval, T. A.; Chae, C.-S.; Cheong, J.-G.; Tan, C.; Iwawaki, T.; Cubillos-Ruiz, J. R.

10.1101/2024.08.05.606646 — immunology — Posted on 2024-08-07

4023 A hidden mark of a troubled past: neuroimaging and transcriptomic analyses reveal interactive effects of maternal immune activation and adolescent THC exposure in the absence of overt behavioural disruptions

Moreno-Fernandez, M.; Lujan, V.; Baliyan, S.; Poza, C.; Capellan, R.; De las Heras, N.; Morcillo, M. A.; Oteo-Vives, M.; Ambrosio, E.; Ucha, M.; Higuera-Matas, A.

10.1101/2024.08.05.606145 — neuroscience — Posted on 2024-08-07

4024 Optic flow density modulates corner-cutting independently of age in a virtual reality steering task

Giguere, A. P.; Huxlin, K. R.; Tadin, D.; Fajen, B. R.; Diaz, G. J.

10.1101/2024.08.05.606519 — neuroscience — Posted on 2024-08-07

4025 The intersection of endocrine signaling and neuroimmune communication regulates neonatal nociception

Fadaka, A. O.; Dourson, A. J.; Hofmann, M. C.; Gupta, P.; Raut, N. G. R.; Jankowski, M. P.

10.1101/2024.07.26.605393 — neuroscience — Posted on 2024-08-07

4026 Neural Processing of Taste-related Signals in the Mediodorsal Thalamus of Mice.

Odegaard, K. E.; Bouaichi, C. G.; Owanga, G.; Vincis, R.

10.1101/2024.08.05.606609 — neuroscience — Posted on 2024-08-07

4027 Standardising a microbiome pipeline for body fluid identification from complex crime scene stains

Swayambhu, M.; Gysi, M.; Haas, C.; Schuh, L.; Walser, L.; Javanmard, F.; Flury, T.; Ahannach, S.; Lebeer, S.; Hanssen, E. N.; Snipen, L.; Bokulich, N.; Kuemmerli, R.; Arora, N.

10.1101/2024.08.05.604586 — bioinformatics — Posted on 2024-08-07

4028 Extensive Surveillance of Mosquitoes and molecular investigation of Arboviruses in central Iran; First Record of Molecular Identification of Culex tarsalis in Qom Province

Abedi-Astaneh, F.; ABBASI, E.; Raoofi Rad, H.; Hassan Pouriayevali, M.; Jalali, T.; Izanlou, H.; Ebrahimi, M.; Salehi Vaziri, M.; Hamta, A.; HosseinAnliPour, S. A.; Eshaghieh, M.; Ansari Cheshmeh, M.; Talbalaghi, A.

10.1101/2024.08.06.606915 — molecular biology — Posted on 2024-08-07

4029 Projection neurons are necessary for the maintenance of the mouse olfactory circuit.

Sanchez-Guardado, L.; Razavi, P.; Wang, B.; Callejas-Marin, A.; Lois, C.

10.1101/2023.08.14.553299 — neuroscience — Posted on 2024-08-07

4030 A modified decision tree improves generalization across multiple brains proteomic data sets and reveals the role of ferroptosis in Alzheimer disease

Ivanov, M. V.; Kopeykina, A. S.; Kazakova, E. M.; Tarasova, I. A.; Sun, Z.; Postoenko, V. I.; Yang, J.; Gorshkov, M. V.

10.1101/2024.08.07.606974 — molecular biology — Posted on 2024-08-07

4031 Biased recruitment of H3.3 by HIRA is dictated by de-/acetylation and determines transcription memory and response

Usha Satheesan, S.; Chakrabarti, S.; Fulzele, A.; Marcellin, M.; Locard-Paulet, M.; Peredo, A. G.-d.; Kolthur-Seetharam, U.

10.1101/2024.08.07.606949 — molecular biology — Posted on 2024-08-07

4032 DROSHA, DICER and Damage-Induced long ncRNA control BMI1-dependent transcriptional repression at DNA double-strand break

Esposito, F.; Capozzo, I.; Modafferi, S.; Gioia, U.; Manfredi, L.; Ianelli, F.; Colantoni, A.; Riccardi, A.; di Lillo, A.; Tavella, S.; Cabrini, M.; d'Adda di Fagagna, F.; Francia, S.

10.1101/2024.08.07.606960 — molecular biology — Posted on 2024-08-07

4033 Predicting murine age across tissues and cell types using single cell transcriptome data

Neumann, J. F.; Leote, A. C. d. S.; Liersch, M.; Beyer, A.

10.1101/2022.10.19.512922 — bioinformatics — Posted on 2024-08-07

4034 Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional WFS1 variant

Torchio, S.; Siracusano, G.; Cuozzo, F.; Zamarian, V.; Pellegrini, S.; Manenti, F.; Bonfanti, R.; Frontino, G.; Sordi, V.; Chimienti, R.; Piemonti, L.

10.1101/2024.08.06.606801 — cell biology — Posted on 2024-08-07

4035 An In-Vitro Standardized Protocol for Preparing Smoke Extract Media from Cigarette, Electronic Cigarette and Waterpipe.

Al-Hashimi, A.; Shah, J.; Carpenter, R.; Morgan, W.; Meah, M.; Ruchaya, P. J.

10.1101/2024.08.07.606957 — cell biology — Posted on 2024-08-07

4036 Transcriptomic profiling of healthy individual-derived LCLs revealed inter-individual variability towards-hypoxia-responsive pathways

Singh, D.; Mehta, K.; Rani, R.; Agrawal, S. K.; Prasher, B.

10.1101/2024.08.06.606933 — cell biology — Posted on 2024-08-07

4037 On the possibility of yet a third kinetochore system in the protist phylum Euglenozoa

Benz, C.; Raas, M. W. D.; Tripathi, P.; Faktorova, D.; Tromer, E. C.; Akiyoshi, B.; Lukes, J.

10.1101/2024.08.06.606595 — cell biology — Posted on 2024-08-07

4038 βA3/A1-crystallin is an epigenetic regulator of histone deacetylase 3 (HDAC3) in the retinal pigmented epithelial (RPE) cells

Chatterjee, S.; Ghosh, S.; Sin, Z.; Davis, E.; Preval, L. V.; Tran, N.; Bammidi, S.; Gautam, P.; Hose, S.; Sergeev, Y.; Flores-Bellver, M.; Al Diri, I.; Sinha, D.; Guha, P.

10.1101/2024.08.06.606634 — cell biology — Posted on 2024-08-07

4039 PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer

Liu, F.; Liu, W.; Tan, Y.; Shang, Y.; Ling, S.; Jiang, X.; Zhang, Z.; Sun, S.; Xie, P.

10.1101/2024.08.06.606911 — cell biology — Posted on 2024-08-07

4040 Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners

Coate, K. C.; Dai, C.; Singh, A. K.; Stanley, J. E.; Covington, B. A.; Bradley, A.; Oladipupo, F. O.; Gong, Y.; Wisniewski, S.; Spears, E. A.; Poffenberger, G.; Bustabad, A.; Rodgers, T. J.; Dey, N.; Schultz, L. D.; Greiner, D. L.; Yan, H.; Powers, A. C.; Chen, W.; Dean, E. D.

10.1101/2024.08.06.606926 — cell biology — Posted on 2024-08-07

4041 Episodic Transport of Protein Aggregates Achieves a Positive Size Selectivity in Aggresome Formation

Fang, R.; Bai, L.; Li, B.; Dong, K.; Paulo, J. A.; Zhou, M.; Chu, Y.-C.; Song, Y.; Sherman, M. Y.; Gygi, S.; Field, C.; Mitchison, T.; Lu, Y.

10.1101/2024.08.06.606767 — cell biology — Posted on 2024-08-07

4042 Mass spectrometric profiling of estrogen and estrogen metabolites in human stool and plasma partially elucidates the role of the gut microbiome in estrogen recycling

Li, V. W.; Dong, T. S.; Funes, D.; Hernandez, L. L.; Reddy, S.; Mayer, E.; Chang, L.; Meriwether, D.

10.1101/2024.08.07.606543 — molecular biology — Posted on 2024-08-07

4043 Neural circuit mechanisms for steering control in walking Drosophila

Rayshubskiy, A.; Holtz, S. L.; Bates, A.; Vanderbeck, Q. X.; Capdevila, L. S.; Wilson, R. I.

10.1101/2020.04.04.024703 — neuroscience — Posted on 2024-08-07

4044 Evidences of an inhibitory effect and other functions of human P53 in Escherichia coli

Ben Abid, S.; Yacoubi, I.; Djemal, L.; Dardouri, M.; Gargouri, A.

10.1101/2024.08.06.606936 — cell biology — Posted on 2024-08-07

4045 mTORC1 Signaling Inhibition Modulates Mitochondrial Function in Frataxin Deficiency

Lehmer, M.; Zoncu, R.

10.1101/2024.08.06.606942 — cell biology — Posted on 2024-08-07

4046 Formation of brain-wide neural geometry during visual item recognition in monkeys

Chen, H.; Kunimatsu, J.; Oya, T.; Imaizumi, Y.; Hori, Y.; Matsumoto, M.; Tsubo, Y.; Hikosaka, O.; Minamimoto, T.; Naya, Y.; Yamada, H.

10.1101/2024.08.05.604527 — neuroscience — Posted on 2024-08-07

4047 Adult Neurogenesis through Glial Transdifferentiation in a CNS Injury Paradigm

Casas-Tinto, S.; Garcia-Guillen, N.; Losada-Perez, M.

10.1101/2024.02.07.579273 — neuroscience — Posted on 2024-08-07

4048 Learning in single cells: biochemically-plausible models of habituation

Eckert, L.; Vidal, M. S.; Zhao, Z.; Garcia-Ojalvo, J.; Martinez-Corral, R.; Gunawardena, J.

10.1101/2024.08.04.606534 — systems biology — Posted on 2024-08-07

4049 Discovery of the first-efficacious A2AR negative allosteric modulators for high adenosine cancer immunotherapies

Boujut, M.; Heritier, M.; Gouiller, A.; Suess, C.; Scapozza, A.; De Smedt, T.; Guibert, M.; Tardy, S.; Hamed, H.; Pejoski, D.; Scapozza, L.

10.1101/2024.08.05.606339 — pharmacology and toxicology — Posted on 2024-08-07

4050 Discovery of ICOS-targeted small molecules using affinity selection mass spectrometry screening

Zhang, L.; Calvo-Barreiro, L.; Batista, V. d. S.; Swiderek, K.; Gabr, M.

10.1101/2024.08.04.606538 — pharmacology and toxicology — Posted on 2024-08-07

4051 The PVT1, HULC, and HOTTIP expression changes due to treatment in Diffuse Large B-cell lymphoma

Shahsavari, M.; Arbabian, S.; Hosseini, F.; Razavi, M. R.

10.1101/2024.08.05.606587 — cancer biology — Posted on 2024-08-07

4052 Pertpy: an end-to-end framework for perturbation analysis

Heumos, L.; Ji, Y.; May, L.; Green, T.; Zhang, X.; Wu, X.; Ostner, J.; Peidli, S.; Schumacher, A.; Hrovatin, K.; Mueller, M.; Chong, F.; Sturm, G.; Tejada, A.; Dann, E.; Dong, M.; Bahrami, M.; Gold, I.; Rybakov, S.; Namsaraeva, A.; Moinfar, A. A.; Zheng, Z.; Roellin, E.; Mekki, I.; Sander, C.; Lotfollahi, M.; Schiller, H. B.; Theis, F. J.

10.1101/2024.08.04.606516 — bioinformatics — Posted on 2024-08-07

4053 Get to know your neighbors with a SNAQ™: A framework for single cell spatial neighborhood analysis in immunohistochemical images

Silver, A.; Chakraborty, A.; Pittu, A.; Feier, D.; Anica, M.; West, I.; Sarkisian, M. R.; Deleyrolle, L. P.

10.1101/2024.08.04.606539 — bioinformatics — Posted on 2024-08-07

4054 CellClear: Enhancing Single-cell RNA Data Quality via Biologically-Informed Ambient RNA Correction

Huang, W.; Hu, L.; Qian, Z.; Fan, J.

10.1101/2024.08.05.606571 — bioinformatics — Posted on 2024-08-07

4055 Ice Finder: Few-Shot Learning for Non-Vitrified Ice Segmentation

Lago, A. V.; Castano Diez, D.

10.1101/2024.08.05.606577 — bioinformatics — Posted on 2024-08-07

4056 GOLEM: A tool for visualizing the distribution of Gene regulatOry eLEMents within the plant promoters with a focus on male gametophyte

Nevosad, L.; Klodova, B.; Racek, T.; Prerovska, T.; Kusova, A.; Svobodova, R.; Honys, D.; Prochazkova Schrumpfova, P.

10.1101/2024.08.05.606583 — bioinformatics — Posted on 2024-08-07

4057 Multimodal electrical impedance tomography and electroencephalography imaging: Does higher skull conductivity resolution in EIT imaging improve accuracy of EEG source localization?

Rimpiläinen, V.; Koulouri, A.

10.1101/2024.08.05.606582 — bioengineering — Posted on 2024-08-07

4058 Nanopore sequencing from protozoa to phages: decoding biological information on a string of biochemical molecules into human-readable signals

Hunter, B.; Cromwell, T.; Shim, H.

10.1101/2024.08.04.606558 — bioengineering — Posted on 2024-08-07

4059 Transocular detection of premotor Parkinson's disease via retinal neurovascular coupling through functional OCT angiography

Liu, K.; Wang, R.; Huang, L.; Zhang, H.; Gao, M.; Sun, B.; Tan, Y.; Ye, J.; Ding, Z.; Gu, Y.; Zhang, S.; Li, P.

10.1101/2024.08.04.606502 — bioengineering — Posted on 2024-08-07

4060 Optimized semi-specific PCR amplification using arbitrarily degenerate primer for genome-wide genotyping and its application in peanut genetic diversity study

Zhao, S.; Wang, Y.; Zhang, X.; Xie, S.; Chen, H.; Yan, Y.; Gu, J.; Chen, P.; Chang, Y.; Xu, Z.

10.1101/2024.08.04.606550 — genomics — Posted on 2024-08-07

4061 Endogenous Retrovirus Loci and Induced Changes in Gene Expression in Japanese Indigenous Chickens

Ishihara, S.; Shiraishi, J.-i.; Shimamoto, S.; Ijiri, D.

10.1101/2024.08.05.606564 — genomics — Posted on 2024-08-07

4062 ERBB2/HOXB13 co-amplification with interstitial deletion of BRCA1 defines a unique subset of breast cancers

Mitsiades, I. R.; Onozato, M.; Iafrate, A. J.; Hicks, D.; Sgroi, D. C.; Rheinbay, E.

10.1101/2024.08.04.605361 — genomics — Posted on 2024-08-07

4063 Blood host preferences and competitive inter-species dynamics within an African malaria vector species complex inferred from signs of animal activity around aquatic larval habitats.

Walsh, K. A.; Kavishe, D. R.; Duggan, L. M.; Tarimo, L. J.; Msoffe, R. V.; Manase, E.; Govella, N. J.; Eichhorn, M. P.; Kaindoa, E. W.; Butler, F.; Killeen, G. F.

10.1101/2024.08.04.606513 — ecology — Posted on 2024-08-07

4064 Quantifying irreversibility of ecological systems

Li, J.; Munch, S. B.; Tan, T. H.; Song, C.

10.1101/2024.08.04.606544 — ecology — Posted on 2024-08-07

4065 Connectivity loss in experimental pond networks leads to biodiversity loss in microbial communities

Szabo, B.; Vaczy-Foldi, M.; Vad, C. F.; Palffy, K.; Huynh, T.-H.; Dobosy, P.; Fierpasz, A.; Marton, Z.; Felfoldi, T.; Horvath, Z.

10.1101/2024.08.05.606584 — ecology — Posted on 2024-08-07

4066 Novel replication-competent reporter-expressing Rift Valley fever viruses for molecular studies

Nogales, A.; Alonso, C.; Moreno, S.; Lorenzo, G.; Borrego, B.; Martinez-Sobrido, L.; Brun, A.

10.1101/2024.08.06.606778 — microbiology — Posted on 2024-08-07

4067 Borrelia burgdorferi BB0346 is an Essential, Structurally Variant LolA Homolog that is Primarily Required for Homeostatic Localization of Periplasmic Lipoproteins

Murphy, B. T.; Wiepen, J. J.; Graham, D. E.; Swanson, S.; Kashipathy, M. M.; Cooper, A.; Battaile, K. P.; Johnson, D. K.; Florens, L.; Blevins, J. S.; Lovell, S.; Zückert, W. R.

10.1101/2024.08.06.606844 — microbiology — Posted on 2024-08-07

4068 Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

Pereira, P.; Panier, J.; Nater, M.; Herbst, M.; Calvanese, A. L.; Koksal, H.; Castanon, H.; Cecconi, V.; Tallon de Lara, P.; Pascolo, S.; van den Broek, M.

10.1101/2024.08.05.606588 — immunology — Posted on 2024-08-07

4069 A Small Interfering Peptide Potentiates AMPA Receptor Diffusional Trapping and Prevents Social-Isolation-Induced Forgetting of Fear Memory

Gundersen, J. E. T.; Wu, X.; Song, J.; Yao, J.; Nesbo, H. H.; Pokharna, A.; Mergiya, T. F.; Liu, H.; Sun, S.; Greger, I.; Wang, C.; Xu, N.-j.; Bramham, C. R.; Zhang, H.

10.1101/2024.08.04.606518 — neuroscience — Posted on 2024-08-07

4070 Sound preferences in mice are sex-dependent

Sehrawat, K.; Nelken, I.

10.1101/2024.08.04.606510 — neuroscience — Posted on 2024-08-07

4071 The scope and limits of fine-grained category information in the ventral visual pathway

Badwal, M. W.; Bergmann, J.; Roth, J.; Doeller, C. F.; Hebart, M. N.

10.1101/2024.08.04.606507 — neuroscience — Posted on 2024-08-07

4072 GBA1 MUTATIONS ALTER THE PHENOTYPE AND BEHAVIOUR OF DOPAMINERGIC NEURONS IN PARKINSON DISEASE, INFLUENCING VGLUT2 AND CRYAB EXPRESSION

Rodriguez-Traver, E.; Suarez, L. M.; Crespo, C.; Gonzalez-Burgos, I.; Vecino, R.; Jurado-Coronel, J. C.; Galan, M.; Gonzalez-Gonzalez, M.; Moratalla, R.; Vicario, C.

10.1101/2024.08.05.606574 — neuroscience — Posted on 2024-08-07

4073 Delineating In-Vivo T1-Weighted Intensity Profiles Within the Human Insula Cortex Using 7-Tesla MRI

Dalby, C.; Dibble, A. J.; Carvalheiro, J.; Queirazza, F.; Sevegnani, M.; Harvey, M.; Svanera, M.; Fracasso, A.

10.1101/2024.08.05.605123 — neuroscience — Posted on 2024-08-07

4074 Computational model for synthesizing auditory brainstem responses to assess neuronal alterations in aging and autistic animal models

Li, B.-Z.; Poleg, S.; Ridenour, M.; Tollin, D.; Lei, T.; Klug, A.

10.1101/2024.08.04.606499 — neuroscience — Posted on 2024-08-07

4075 Circular RNAs exhibit exceptional stability in the aging brain and serve as reliable age and experience indicators

Kirio, K.; Patop, I. L.; Martin Anduaga, A.; Harris, J.; Pamudurti, N.; Martel, C.; Kadener, S.

10.1101/2024.08.04.606529 — neuroscience — Posted on 2024-08-07

4076 What works to improve species conservation state? An analysis of species whose state has improved and the actions responsible

Simkins, A. T.; Sutherland, W. J.; Dicks, L. V.; Hilton-Taylor, C.; Grace, M. K.; Butchart, S. H. M.; Senior, R. A.; Petrovan, S. O.

10.1101/2024.08.04.606320 — zoology — Posted on 2024-08-07

4077 Twisted Sister1: an agravitropic mutant of bread wheat (Triticum aestivum) with altered root and shoot architectures.

Zeng, D.; Peng, J.; Zhang, L.; Hayden, M. J.; Rathjen, T.; Zhu, B.; Zeng, Z.; Delhaize, E.

10.1101/2024.08.04.606531 — plant biology — Posted on 2024-08-07

4078 Improved Degradome Sequencing Protocol via Reagent Recycling from sRNAseq Library Preparations

Puchta-Jasinska, M.; Groszyk, J.; Boczkowska, M.

10.1101/2024.08.04.606535 — plant biology — Posted on 2024-08-07

4079 Single component CRISPR-mediated base-editors for Agrobacterium and their use to develop an improved suite of strains

Pennetti, V. J.; LaFayette, P. R.; Parrott, W. A.

10.1101/2024.08.04.606528 — plant biology — Posted on 2024-08-07

4080 Regulation of Ferroptosis in Obesity: Muscle Type-Specific Effects of Dietary Restriction and Exercise

Ji, F.; Park, Y. J.; Lee, H.; Kim, J.-H.

10.1101/2024.08.04.605473 — physiology — Posted on 2024-08-07

4081 Prenatal Dexamethasone Programs Autonomic Dysregulation in Female Rats

Madhavpeddi, L.; Martinez, M.; Alvarez, J.; Sharma, A.; Hu, C.; Tobet, S. A.; Hale, T. M.

10.1101/2024.08.05.606452 — physiology — Posted on 2024-08-07

4082 From Virtual Screens to Cellular Target Engagement: New Small Molecule Ligands for the Immune Checkpoint LAG-3

Fuchs, N.; Calvo-Barreiro, L.; Talagayev, V.; Pach, S.; Wolber, G.; Gabr, M.

10.1101/2024.08.04.604031 — pharmacology and toxicology — Posted on 2024-08-07

4083 Attenuation of Atherosclerosis with PAR4 Deficiency: Differential Platelet Outcomes in apoE-/- vs. Ldlr-/- Mice

Wadding-Lee, C.; Jay, M.; Shearer, S. M.; Benson, T.; Spuzzillo, A.; Howatt, D. A.; Thompson, J.; Daugherty, A.; Mackman, N.; Owens, A. P.

10.1101/2024.08.01.606266 — pathology — Posted on 2024-08-07

4084 Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse

Fu, R.; Su, H. A.; Tian, Y.; Chen, H.; Lu, D.

10.1101/2024.07.03.601978 — cancer biology — Posted on 2024-08-07

4085 Identifying Differential Spatial Expression Patterns across Different Slices, Conditions and Developmental Stages with Interpretable Deep Learning

Cui, Y.; Yuan, Z.

10.1101/2024.08.04.606512 — bioinformatics — Posted on 2024-08-07

4086 Massively parallel quantification of substrate turnover defines protease subsite cooperativity

Gudipati, R. K.; Gaidatzis, D.; Seebacher, J.; Muehlhaeusser, S.; Kempf, G.; Cavadini, S.; Hess, D.; Soneson, C.; Grosshans, H.

10.1101/2023.11.17.567387 — biochemistry — Posted on 2024-08-07

4087 A new class of receptors: Lipids regulate mammalian Gsalpha-stimulated adenylyl cyclase activities via their membrane anchors

Landau, M.; Elsabbagh, S.; Gross, H.; Fuchs, A. C. D.; Schultz, A.; Schultz, J. E.

10.1101/2024.08.06.606792 — biochemistry — Posted on 2024-08-07

4088 Distinguishing multiple-merger from Kingman coalescence using two-site frequency spectra

Fenton, E. F.; Rice, D. P.; Novembre, J.; Desai, M. M.

10.1101/461517 — evolutionary biology — Posted on 2024-08-07

4089 Computing hematopoiesis plasticity in response to genetic mutations and environmental stimulations

Wen, Y.; He, H.; Ma, Y.; Cai, L. C.; Wang, H.; Li, Y.; Zhao, B.; Cai, Z.

10.1101/2024.08.02.606315 — developmental biology — Posted on 2024-08-07

4090 From insect endosymbiont to phloem colonizer: comparative genomics unveils the lifestyle transition of phytopathogenic Arsenophonus strains

Mahillon, M.; Debonneville, C.; Groux, R.; Roquis, D.; Brodard, J.; Faoro, F.; Foissac, X.; Schumpp, O.; Dittmer, J.

10.1101/2024.08.06.606843 — microbiology — Posted on 2024-08-07

4091 GBP2 engages Galectin-9 for immunity against Toxoplasma gondii

Kravets, E.; Poschmann, G.; Haensch, S.; Raba, V.; Weidtkamp-Peters, S.; Degrandi, D.; Stuehler, K.; Pfeffer, K.

10.1101/2021.12.28.474342 — immunology — Posted on 2024-08-07

4092 Pathophysiological response in experimental trauma-related acute kidney injury

Halbgebauer, R.; Schult, L.; Borgel, O.; Maes, A.; Weisshaupt, F.; Rastner, C.; Ast, A.; Lupu, L.; Palmer, A.; Wachter, U.; Schmidt, S. A.; Boor, P.; Rösler, R.; Wiese, S.; Kerckhofs, G.; Huber-Lang, M.

10.1101/2024.08.02.606294 — pathology — Posted on 2024-08-07

4093 Dual-Targeted Microbubbles Promote Apoptosis of M1 Macrophages by Inhibiting Telomerase Activity for Atherosclerosis Therapy

Liu, Y.; Zeng, W.; Huang, Z.; Huang, Y.; Xiong, K.; Sheng, Y.; Lin, X.; Zhong, X.; Ye, J.; Guo, Y.; Arkin, G.; Xu, J.; Fei, H.

10.1101/2024.08.01.606265 — bioengineering — Posted on 2024-08-07

4094 Rapid reprogramming and stabilisation of homoeolog expression bias in hexaploid wheat biparental populations

Glombik, M.; Arunkumar, R.; Burrows, S.; Mogg, S. L.; Wang, X.; Borrill, P.

10.1101/2024.08.01.606180 — plant biology — Posted on 2024-08-07

4095 RBM3 enhances cold resistance by regulating thermogenic gene expressions

Nakamura, J.; Uno, M.; Taketomi, T.; Yadav, M. K.; Tsuruta, F.

10.1101/2023.05.10.540283 — physiology — Posted on 2024-08-07

4096 Caliban: Accurate cell tracking and lineage construction in live-cell imaging experiments with deep learning

Schwartz, M.; Moen, E.; Miller, G.; Dougherty, T.; Borba, E.; Ding, R.; Graf, W.; Pao, E.; Van Valen, D. A.

10.1101/803205 — bioinformatics — Posted on 2024-08-07

4097 LukProt: A database of eukaryotic predicted proteins designed for investigations of animal origins

Sobala, Łukasz F.

10.1101/2024.01.30.577650 — bioinformatics — Posted on 2024-08-07

4098 Rapid and Sensitive Protein Complex Alignment with Foldseek-Multimer

Kim, W.; Mirdita, M.; Karin, E. L.; Gilchrist, C. L. M.; Schweke, H.; Soeding, J.; Levy, E.; Steinegger, M.

10.1101/2024.04.14.589414 — bioinformatics — Posted on 2024-08-07

4099 A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on β cell apoptosis in a patient with Wolfram syndrome.

Chimienti, R.; Torchio, S.; Siracusano, G.; Zamarian, V.; Monaco, L.; Lombardo, M. T.; Pellegrini, S.; Manenti, F.; Cuozzo, F.; Rossi, G.; Carrera, P.; Sordi, V.; Broccoli, V.; Bonfanti, R.; Casari, G.; Frontino, G.; Piemonti, L.

10.1101/2023.12.29.573188 — genetics — Posted on 2024-08-07

4100 An Information Theory Framework for Movement Path Segmentation and Analysis

Sethi, V.; Spiegel, O.; Salter, R.; Cain, S.; Toledo, S.; Getz, W.

10.1101/2024.08.02.606194 — ecology — Posted on 2024-08-07

4101 Nanoscale cluster mapping of molecular complexes with pixel-based correlations

Kiuchi, T.; Kobayashi, R.; Ogawa, S.; Elverston, L. L.; Watanabe, N.

10.1101/2024.07.02.601646 — cell biology — Posted on 2024-08-07

4102 Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells

Kakade, A. A.; Gupta, S.; Varghese, R.; Adicherla, H.; Nagarkar-Jaiswal, S.

10.1101/2024.07.20.604396 — cell biology — Posted on 2024-08-07

4103 TOMOMAN: a software package for large scale cryo-electron tomography data preprocessing, community data sharing, and collaborative computing

Khavnekar, S.; Erdmann, P. S.; Wan, W.

10.1101/2024.05.02.589639 — molecular biology — Posted on 2024-08-07

4104 Wildlife as a sentinel for pathogen introduction in nonendemic areas: first detection of Leishmania tropica in wildlife in Spain

Azami-Conesa, I.; Matas Mendez, P.; Perez-Moreno, P.; Carrion, J.; Alunda, J. M.; Mateo Barrientos, M.; Gomez_Munoz, M. T.

10.1101/2024.03.16.585353 — microbiology — Posted on 2024-08-07

4105 SICKO: Systematic Imaging of Caenorhabtidis Killing Organisms

Espejo, L. S.; Freitas, S.; Silbar, V.; Chang, L.; Balsa, J.; Antenor, A.; Dang, H.; DeNicola, D.; Sutphin, G. L.

10.1101/2023.02.17.529009 — immunology — Posted on 2024-08-07

4106 Helminth-derived metabolites induce tolerogenic functional, metabolic, and transcriptional signatures in dendritic cells that attenuate experimental colitis

Malacco, N. L.; Michi, A. N.; Siciliani, E.; Madrigal, A. G.; Sternlieb, T.; Fontes, G.; King, I. L.; Cestari, I.; Jardim, A.; Stevenson, M. M.; Lopes, F.

10.1101/2023.01.26.525718 — immunology — Posted on 2024-08-07

4107 Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits

Peck, E. G.; Holleran, K. M.; Curry, A. M.; Holter, K. M.; Estave, P.; Sens, J. P.; Locke, J.; Ortelli, O.; George, B.; Dawes, M.; West, A. M.; Alexander, N.; Kiraly, D. D.; Farris, S.; Gould, R. W.; McCool, B.; Jones, S. R.

10.1101/2024.07.27.605436 — neuroscience — Posted on 2024-08-07

4108 Synaptic Potentiation of Engram cells is Necessary and Sufficient for Context Fear Memory

Cardozo, L. M.; Sousa, A. F.; Dillingham, B. C.; Dang, W.; Job, N.; Yoo, E. J.; Ranamukhaarachchi, S. K.; Yuan, Q.; Mayford, M.

10.1101/2022.01.09.475530 — neuroscience — Posted on 2024-08-07

4109 Neural signatures of attentional prioritization and facilitation in accessing repeated items inVisual Working memory

Narvaria, A. S.; Banerjee, A.; Roy, D.

10.1101/2023.08.18.553911 — neuroscience — Posted on 2024-08-07

4110 The distribution of particulate organic matter in the heterogeneous soil matrix - balancing between aerobic respiration and denitrification

Lucas, M.; Rohe, L.; Apelt, B.; Stange, C. F.; Vogel, H.-J.; Well, R.; Schlüter, S.

10.1101/2024.03.16.585355 — plant biology — Posted on 2024-08-07

4111 Clonal evolutionary analysis reveals patterns of malignant transformation in pancreatic cancer from Intraductal Papillary Mucinous IPMN Neoplasms (IPMN)

Pea, A.; He, X.; Upstill-Goddard, R.; Luchini, C.; Santana, L. P. S.; Dreyer, S.; Jamieson, N.; Duthie, F.; MacKay, C.; Dickson, E.; Pulvirenti, A.; Rebus, S.; Genomics Innovation Alliance, ; Scottish Genome Partnership, ; Piccoli, P.; Sperandio, N.; Lawlor, R.; Milella, M.; Froeling, F.; Salvia, R.; Scarpa, A.; Bainkin, A.; Wedge, D.; Chang, D.

10.1101/2024.08.02.606217 — cancer biology — Posted on 2024-08-07

4112 Shape dynamics and migration of branched cells on complex networks

Liu, J.; Boix-Campos, J.; Ron, J. E.; Kux, J. M.; Oremek, M. E. M.; Rossi, A. G.; Gov, N.; Saez, P. J.

10.1101/2024.03.29.585638 — biophysics — Posted on 2024-08-07

4113 A circadian behavioral analysis suite for real-time classification of daily rhythms in complex behaviors

Perry, L. J.; Perez, B. E.; Rays Wahba, L.; Nikhil, K.; Lenzen, W. C.; Jones, J. R.

10.1101/2024.02.23.581778 — animal behavior and cognition — Posted on 2024-08-07

4114 Altered spawning seasons of Atlantic salmon broodstock transcriptionally and epigenetically influence cell cycle and lipid-mediated regulations in their offspring

Saito, T.; Espe, M.; Mommens, M.; Bock, C.; Fernandes, J. M. O.; Skjaerven, K. H.

10.1101/2024.02.03.578741 — genomics — Posted on 2024-08-07

4115 Microbial diversification is maintained in an experimentally evolved synthetic community.

Al-Tameemi, Z.; Rodriguez-Verdugo, A.

10.1101/2024.03.27.587025 — evolutionary biology — Posted on 2024-08-07

4116 Evolutionary dynamics of nascent multicellular lineages

Doulcier, G.; Remigi, P.; Rexin, D.; Rainey, P. B.

10.1101/2024.05.10.593459 — evolutionary biology — Posted on 2024-08-07

4117 modelRxiv: A platform for the dissemination and interactive display of models

Harris, K. D.; Hadari, G.; Greenbaum, G.

10.1101/2022.02.16.480599 — ecology — Posted on 2024-08-07

4118 An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus

Cattle, M. A.; Aguado, L. C.; Sze, S.; Wang, D. Y.; Papagiannakopoulos, T.; Smith, S.; Rice, C. M.; Schneider, W. M.; Poirier, J. T.

10.1101/2024.08.05.606586 — molecular biology — Posted on 2024-08-07

4119 Laboratory evolution of E. coli with a natural vitamin B12 analog reveals roles for cobamide uptake and adenosylation in methionine synthase-dependent growth

Mok, K. C.; Hallberg, Z.; Procknow, R. R.; Taga, M. E.

10.1101/2024.01.04.574217 — microbiology — Posted on 2024-08-07

4120 Homeostasis of cytoplasmic crowding by cell wall fluidization and ribosomal counterions

Mukherjee, A.; Huang, Y.; Oh, S.; Sanchez, C.; Chang, Y.-F.; Liu, X.; Bradshaw, G. A.; Benites, N. C.; Paulsson, J.; Kirschner, M. W.; Sung, Y.; Elgeti, J.; Basan, M.

10.1101/2023.08.31.555748 — microbiology — Posted on 2024-08-07

4121 Altered activity of mPFC pyramidal neurons and parvalbumin-expressing interneurons during social interactions in a Mecp2 mouse model for Rett syndrome

Medeiros, D.; Polepalli, L.; Li, W.; Pozzo-Miller, L.

10.1101/2024.08.06.606882 — neuroscience — Posted on 2024-08-06

4122 Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex

Burns, J. N.; Jenkins, A. K.; Yin, R.; Zong, W.; Vadnie, C. A.; DePoy, L.; Petersen, K. A.; Tsyglakova, M.; Scott, M. R.; Tseng, G.; Huang, Y. H.; McClung, C. A.

10.1101/2024.07.05.601880 — neuroscience — Posted on 2024-08-07

4123 Enhanced EEG Forecasting: A Probabilistic Deep Learning Approach

Pankka, H.; Lehtinen, J.; Ilmoniemi, R.; Roine, T.

10.1101/2024.01.16.575836 — neuroscience — Posted on 2024-08-07

4124 Guanylate cyclase activity of TIR1/AFB auxin receptorsin rapid auxin responses

Qi, L.; Kwiatkowski, M.; Kulich, I.; Chen, H.; Gao, Y.; Yun, P.; Li, L.; Shabala, S.; Farmer, E.; Jaworski, K.; Friml, J.

10.1101/2023.11.18.567481 — plant biology — Posted on 2024-08-07

4125 Astrocyte extracellular matrix modulate neuronal dendritic development

Hashimoto, J. G.; Margolies, N.; Zhang, X.; Karpf, J.; Song, Y.; Davis, B. A.; Zhang, F.; Linhardt, R. J.; Carbone, L.; Guizzetti, M.

10.1101/2024.08.06.606424 — neuroscience — Posted on 2024-08-06

4126 Sphingosine-1-phosphate signaling regulates the ability of Müller glia to become neurogenic, proliferating progenitor-like cells

Taylor, O.; DeGroff, N.; El-Hodiri, H.; Gao, C.; Fischer, A. J.

10.1101/2024.08.06.606815 — neuroscience — Posted on 2024-08-06

4127 Aperiodic and oscillatory systems underpinning human domain-general cognition

Lu, R.; Dermody, N.; Duncan, J.; Woolgar, A.

10.1101/2024.08.06.606820 — neuroscience — Posted on 2024-08-06

4128 Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke opposite motor and valence behaviors.

Fallah, M.; Udobi, K. C.; Swiatek, A. E.; Scott, C. B.; Evans, R. C.

10.1101/2024.08.05.606694 — neuroscience — Posted on 2024-08-06

4129 Early life stress induced sex-specific changes in behavior is paralleled by altered locus coeruleus physiology in BALB/cJ mice

Brannan, S. G.; Garbe, L.; Richardson, B. D.

10.1101/2024.08.06.606908 — neuroscience — Posted on 2024-08-06

4130 All of Us diversity and scale improve polygenic prediction contextually with greatest improvements for underrepresented populations

Tsuo, K.; Shi, Z.; Ge, T.; Mandla, R.; Hou, K.; Ding, Y.; Pasaniuc, B.; Wang, Y.; Martin, A. R.

10.1101/2024.08.06.606846 — genomics — Posted on 2024-08-06

4131 Pleiotropy increases parallel selection signatures during adaptation from standing genetic variation

Lai, W.-Y.; Hsu, S.-K.; Futschik, A.; Schloetterer, C.

10.1101/2024.08.06.606803 — evolutionary biology — Posted on 2024-08-06

4132 Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling

Segura-Roman, A.; Citron, Y. R.; Shin, M.; Sindoni, N.; Maya-Romero, A.; Rapp, S.; Goul, C. S.; Mancias, J. D.; Zoncu, R.

10.1101/2024.08.06.606738 — cell biology — Posted on 2024-08-06

4133 Temporally restricted activities of En1 regulatory elements underlie distinct limb malformations

Ringel, A. R.; Magg, A.; Benetti, N.; Schoepflin, R.; Kuehnlein, M. N.; Stiege, A. C.; Fischer, U.; Wittler, L.; Lorenz, S.; Mundlos, S.; Allou, L.

10.1101/2024.08.06.606766 — developmental biology — Posted on 2024-08-06

4134 Complex impact of stimulus envelope on motor synchronization to sound

Sun, Y.; Michalareas, G.; Ghitza, O.; Poeppel, D.

10.1101/2024.08.06.606724 — neuroscience — Posted on 2024-08-06

4135 Novel IF1 mechanism preventing ATP hydrolysis by the ATP synthase subcomplex in Saccharomyces cerevisiae

Lerouley, O.; Larrieu, I.; Pinson, B.; Giraud, M.-F.; Mourier, A.

10.1101/2024.08.06.606758 — biochemistry — Posted on 2024-08-06

4136 Locating the Missing Chlorophylls f in Far-red Photosystem I

Consoli, G.; Tufail, F.; Leong, H. F.; Viola, S.; Davis, G. A.; Medranda, D.; Rew, N.; Hofer, M.; Simpson, P.; Sandrin, M.; Chachuat, B.; Nelson, J.; Renger, T.; Murray, J. W.; Fantuzzi, A.; Rutherford, A. W.

10.1101/2024.08.06.606606 — biochemistry — Posted on 2024-08-06

4137 Defining short linear motif binding determinants by phage-based multiplexed deep mutational scanning

Benz, C.; Maasen, L.; Simonetti, L.; Mihalic, F.; Lindqvist, R.; Tsitsa, I.; Jemth, P.; Overby, A. K.; Davey, N. E.; Ivarsson, Y.

10.1101/2024.08.06.606761 — biochemistry — Posted on 2024-08-06

4138 The potential of regulatory variant prediction AI models to improve cattle traits

Zhao, R.; Owen, R.; Marr, M.; Jayaraman, S.; Chue Hong, N.; Talenti, A.; Hassan, M. A.; Prendergast, J.

10.1101/2024.08.01.606140 — genomics — Posted on 2024-08-06

4139 Functions of PMS2 and MLH1 important for regulation of divergent repeat-mediated deletions

Trost, H.; Lopezcolorado, F. W.; Merkell, A.; Stark, J. M.

10.1101/2024.08.05.606388 — molecular biology — Posted on 2024-08-06

4140 A Strain of Streptococcus mitis Inhibits Biofilm Formation of Caries Pathogens via Abundant Hydrogen Peroxide Production

Williams, I.; Tuckerman, J. S.; Peters, D. I.; Bangs, M.; Williams, E.; Shin, I. J.; Kaspar, J. R.

10.1101/2024.08.06.606862 — microbiology — Posted on 2024-08-06

4141 Interspecies recombination between cassava brown streak disease-causing viruses

Astacio-Berrios, K.; Duffy, S.

10.1101/2024.08.06.606877 — microbiology — Posted on 2024-08-06

4142 Selective epigenetic regulation of IFN-γ signature genes by JAK inhibitor in inflammatory diseases

Kwon, G.; Park, Y.; Kang, K.; Kang, K.

10.1101/2024.08.05.606293 — immunology — Posted on 2024-08-06

4143 Evaluation of High-Affinity Monoclonal Antibodies and Antibody-Drug Conjugates by Homogenous Time-Resolved FRET

Greenway, H.; Wang, J.

10.1101/2024.08.05.606727 — biochemistry — Posted on 2024-08-06

4144 ThermoTargetMiner as a proteome integral solubility alteration target database for prospective drugs against lung cancer

Lyu, H.; Gharibi, H.; Sokolova, B.; Voiland, A.; Nilsson, B.; Meng, Z.; Gaetani, M.; Saei, A. A.; Zubarev, R.

10.1101/2024.08.06.606599 — biochemistry — Posted on 2024-08-06

4145 Metabolic Segregation and Characteristic Genes of the Key Functional Populations in Anaerobic Digestion Consortia

Wang, Y.; Zhang, R.; Wang, C.; Yan, W.; Zhang, T.; Ju, F.

10.1101/2024.08.04.606487 — genomics — Posted on 2024-08-06

4146 PCL-seq: enhanced high-resolution transcriptomic profiling of region of interest in fresh frozen and FFPE tissues

Shi, W.; Dong, X.; Cui, X.; Hu, M.; Zhou, W.

10.1101/2024.08.05.606746 — genomics — Posted on 2024-08-06

4147 A humanized yeast model for studying TRAPP complex mutations; proof-of-concept using variants from an individual with a TRAPPC1-associated neurodevelopmental syndrome

Zykaj, E.; Abboud, C.; Asadi, P.; Warsame, S.; Greco, B.; Lopez-Sanchez, M.; Bratkovic, D.; Kachroo, A.; Perez-Jurado, L. A.; Sacher, M.

10.1101/2024.08.04.605925 — genetics — Posted on 2024-08-06

4148 Antiviral Mx proteins have an ancient origin and widespread distribution among eukaryotes

Langley, C. A.; Dietzen, P. A.; Emerman, M.; Tenthorey, J. L.; Malik, H. S.

10.1101/2024.08.06.606855 — evolutionary biology — Posted on 2024-08-06

4149 Allele ages provide limited information about the strength of negative selection

Shastry, V.; Berg, J. J.

10.1101/2024.08.06.606888 — evolutionary biology — Posted on 2024-08-06

4150 Spatiotemporal Characterization of Cyclooxygenase Pathway Enzymes During Vertebrate Embryonic Development

Leathers, T. A.; Ramarapu, R.; Rogers, C. D.

10.1101/2024.08.02.606390 — developmental biology — Posted on 2024-08-06

4151 Dysfunction of telomeric Cdc13-Stn1-Ten1 simultaneously activates the DNA damage and spindle checkpoints

Grandin, N.; Charbonneau, M.

10.1101/2024.08.06.606774 — molecular biology — Posted on 2024-08-06

4152 Viral piracy of host RNA phosphatase DUSP11 by avipoxviruses

Szymanik, K. H.; Hancks, D. C.; Sullivan, C. S.

10.1101/2024.08.06.606876 — molecular biology — Posted on 2024-08-06

4153 RIPK4 driven by TP53 mutations promotes resistance to redox stress of CRC by phosphorylating MTHFD1

Yu, L.; Zhou, S.; Xu, Y.; Zhang, Z.; Cheng, X.; Zhou, C.; Li, W.; He, J.; Ou, Q.; Qin, J.; Fang, Y.-J.; Peng, J.; Lin, J.-Z.; Lin, B.; Hou, Z.; Pan, Z.

10.1101/2024.08.06.606759 — molecular biology — Posted on 2024-08-06

4154 In-cell structural insight into the asymmetric assembly of central apparatus in mammalian sperm axoneme

Zhu, Y.; Yin, G.; Tai, L.; Wang, B.; Lu, Y.; Zhang, Z.; Chen, S.-R.; Sun, F.

10.1101/2024.08.06.606614 — molecular biology — Posted on 2024-08-06

4155 The Cryptococcus neoformans STRIPAK complex controls genome stability, sexual development, and virulence

Peterson, P. P.; Choi, J.-T.; Fu, C.; Cowen, L. E.; Sun, S.; Bahn, Y.-S.; Heitman, J.

10.1101/2024.08.06.606879 — microbiology — Posted on 2024-08-06

4156 Relative Distribution of DnaA and DNA in Escherichia coli Cells as a Factor of Their Phenotypic Variability

Namboodiri, S. K.; Aranovich, A.; Hadad, U.; Gheber, L. A.; Feingold, M.; Fishov, I.

10.1101/2024.08.06.606784 — microbiology — Posted on 2024-08-06

4157 Inside Out: the physiology of Brucella Vegetative and Intracellular Growth.

Wade, N.; Comerci, D. J.; Soler-Bistue, A.; Marchesini, M. I.

10.1101/2024.08.06.606627 — microbiology — Posted on 2024-08-06

4158 Monosaccharides Drive Salmonella Gut Colonization in a Context-Dependent Manner

Schubert, C.; Nguyen, B. D.; Sichert, A.; Naepflin, N.; Sintsova, A.; Feer, L.; Naef, J.; Daniel, B. B. J.; Steiger, Y.; von Mering, C.; Sauer, U.; Hardt, W.-D.

10.1101/2024.08.06.606610 — microbiology — Posted on 2024-08-06

4159 A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity

Kok, A.; Wilks, S. H.; Tureli, S.; James, S. L.; Bestebroer, T. M.; Burke, D. F.; Funk, M.; van der Vliet, S.; Spronken, M. I.; Rijnink, W. F.; Pattinson, D. J.; de Meulder, D.; Rosu, M. E.; Lexmond, P.; van den Brand, J. M. A.; Herfst, S.; Smith, D. J.; Fouchier, R. A. M.; Richard, M.

10.1101/2024.08.06.606696 — microbiology — Posted on 2024-08-06

4160 Models of microbiome evolution incorporating host resource provisioning

Xiao, Y.; Li, T.; Rodrigo, A. G.

10.1101/2024.08.05.606723 — microbiology — Posted on 2024-08-06

4161 A small regulatory RNA controls antibiotic tolerance in Staphylococcus aureus by modulating efflux pump expression

Bouloc, P.; Ha, K. P.

10.1101/2024.08.05.606701 — microbiology — Posted on 2024-08-06

4162 Nutrient competition predicts gut microbiome restructuring under drug perturbations

Shi, H.; Newton, D. P.; Nguyen, T. H.; Estrela, S.; Sanchez, J.; Tu, M.; Ho, P.-Y.; Zeng, Q.; DeFelice, B.; Sonnenburg, J. L.; Huang, K. C.

10.1101/2024.08.06.606863 — microbiology — Posted on 2024-08-06

4163 Drug-controlled CAR-T cells through the regulation of cell-cell interactions

Scheller, L.; Attianese, G. M. P. G.; Castellanos-Rueda, R.; Di Roberto, R. B.; Barden, M.; Riboulet, M.; Shui, S.; Cribioli, E.; Marchand, A.; Georgeon, S.; Abken, H.; Reddy, S.; Correia, B.; Irving, M.

10.1101/2024.08.06.606454 — synthetic biology — Posted on 2024-08-06

4164 Engineering synthetic agonists for targeted activation of Notch signaling

Luca, V. C.; Perez, D. H.; Antfolk, D.; Medina, E.; Gonzalez-Perez, D.

10.1101/2024.08.06.606897 — synthetic biology — Posted on 2024-08-06

4165 A COVID-19 Rapid Antigen Test Employing Upconversion Nanoparticles

Zhang, L.; Zhou, J.; Shimoni, O.; Wen, S.; Alghalayini, A.; Liu, Y.; Rezaeishahmirzadi, M.; Liao, J.; Maddahfar, M.; Hunt, R.; Black, M.; Johansen, M. D.; Hansbro, P. M.; Zhang, L.; Stenzel, M.; Warkiani, M. E.; Valenzuela, S. M.; Jin, D.

10.1101/2024.08.05.606725 — bioengineering — Posted on 2024-08-06

4166 Measuring heritability in messy prebiotic chemical systems

Sokolskyi, T.; Gargulak, S.; Allen, E.; Baum, D. A.

10.1101/2024.08.03.606486 — evolutionary biology — Posted on 2024-08-06

4167 Evolution and Diversification of the Aposematic Poison Frog, Oophaga pumilio, in Bocas del Toro

Aguilar-Gomez, D.; Freeborn, L.; Yuan, L.; Smith, L. L.; Guzman, A.; Vaughn, A.; Steigerwald, E.; Stuckert, A.; Yang, Y.; Linderoth, T. P.; MacManes, M.; Richards-Zawacki, C. L.; Nielsen, R.

10.1101/2024.08.02.606438 — evolutionary biology — Posted on 2024-08-06

4168 Human Vascularized Macrophage-Islet Organoids to Model Immune-Mediated Pancreatic β cell Pyroptosis upon Viral Infection

Yang, L.; Han, Y.; Zhang, T.; Dong, X.; Ge, J.; Roy, A.; Zhu, J.; Lu, T.; Vandana, J. J.; de Silva, N.; Robertson, C. C.; Xiang, J. Z.; Pan, C.; Sun, Y.; Que, J.; Evans, T.; Liu, C.; Wang, W.; Naji, A.; Parker, S. C. J.; Schwartz, R. E.; Chen, S.

10.1101/2024.08.05.606734 — developmental biology — Posted on 2024-08-06

4169 On the same side: The immune regulatory protein Vista and its ligands interact in cis

Smorodinsky-Atias, K.; Wiseglass, G.; Salem, M.; Kashani, M.; Boni, N.; Artyukhova, A.; Levy, R.; Rubinstein, R.

10.1101/2024.08.02.606340 — immunology — Posted on 2024-08-06

4170 Synergistic control of axon regeneration and functional recovery by let-7 miRNA and Insulin signalling (IIs) pathways

Ravivarma, S.; Behera, S.; Roy, D.; Ghosh-Roy, A.

10.1101/2024.08.03.606500 — neuroscience — Posted on 2024-08-06

4171 A preliminary investigation into the effects of a soluble dietary fibre and mineral formulation on post-prandial glucose regulation and satiation in healthy adults

haynes, m. m.

10.1101/2024.08.03.606479 — physiology — Posted on 2024-08-06

4172 3D histology reveals that immune response to pancreatic precancers is heterogeneous and depends on global pancreas structure

Kiemen, A. L.; Almagro Perez, C.; Matos Romero, V.; Forjaz, A.; Braxton, A. M.; Dequiedt, L.; Parksong, J.; Cannon, C. D.; Yuan, X.; Shin, S. M.; Mahesh Babu, J.; Thompson, E. D.; Cornish, T. C.; Ho, W. J.; Wood, L. D.; Wu, P.; Munoz-Barrutia, A.; Hruban, R. H.; Wirtz, D.

10.1101/2024.08.03.606493 — cancer biology — Posted on 2024-08-06

4173 MAC: An Artifact Correction Framework for Brain MRI based on Deep Neural Networks

Oliveira, A.; Cepa, B.; Brito, C.; Sousa, A.

10.1101/2024.08.02.606374 — bioinformatics — Posted on 2024-08-06

4174 UniPTM: Multiple PTM site prediction on full-length protein sequence

Meng, L.; Lin, J.; Cheng, K.; Xu, K.; Sun, H.; Wong, K.-C.

10.1101/2024.08.03.606471 — bioinformatics — Posted on 2024-08-06

4175 Comparison of Commercially Available Thermostable DNA Polymerases with Reverse-Transcriptase Activity in Coupled Reverse-Transcription Polymerase Chain Reaction Assays

Smirnova, E. V.; Blagodatskikh, K. A.; Barsova, E. V.; Varlamov, D. A.; Kramarov, V. M.; Ignatov, K. B.

10.1101/2024.08.03.606463 — bioengineering — Posted on 2024-08-06

4176 Refining gene delivery to skeletal muscle with a dual-strategy approach of muscle-tropic AAV capsids and muscle-specific promoters.

Darbey, A.; Jin, W.; Greensmith, L.; Sleigh, J. N.; Counsell, J.; Fratta, P.

10.1101/2024.08.02.605568 — bioengineering — Posted on 2024-08-06

4177 Decoding the Dewlap: Multiple signals in females and males of a gliding lizard

Sharma, A. D.; Sridharan, A.; Isvaran, K.

10.1101/2024.08.04.606559 — animal behavior and cognition — Posted on 2024-08-06

4178 The splicing modulator CLK1 is a candidate oncogenic dependency in pediatric high-grade gliomas

10.1101/2024.08.03.606419 — genomics — Posted on 2024-08-06

4179 Probabilistic classification of gene-by-treatment interactions on molecular count phenotypes

Harigaya, Y.; Matoba, N.; Le, B. D.; Valone, J. M.; Stein, J. L.; Love, M. I.; Valdar, W. I.

10.1101/2024.08.03.605142 — genetics — Posted on 2024-08-06

4180 Reduced function of the adaptor SH2B3 promotes T1D via altered γc cytokine-regulated, T cell intrinsic immune tolerance

Watson, T. K.; Rosen, A. B.; Drow, T.; Medjo, J. A.; MacQuivey, M. A.; Ge, Y.; Liggitt, H. D.; Grosvenor, D. A.; Dill-McFarland, K. A.; Altman, M. C.; Concannon, P. J.; Buckner, J. H.; Rawlings, D. J.; Allenspach, E. J.

10.1101/2024.08.02.606362 — immunology — Posted on 2024-08-06

4181 PD-1 controls differentiation, survival, and TCR affinity evolution of stem-like CD8+ T cells

Hor, J. L.; Schrom, E. C.; Wong-Rolle, A.; Vistain, L.; Shang, W.; Dong, Q.; Zhao, C.; Jin, C.; Germain, R. N.

10.1101/2024.08.02.606241 — immunology — Posted on 2024-08-06

4182 Dynamic adaptation to novelty in the brain is related to arousal and intelligence

Tanner, J. C.; Faskowitz, J.; Kennedy, D. P.; Betzel, R.

10.1101/2024.08.02.606380 — neuroscience — Posted on 2024-08-06

4183 TAM receptors mediate the Fpr2-driven pain resolution and fibrinolysis after nerve injury

Hartmannsberger, B.; Ben-Kraiem, A.; Kramer, S.; Guidolin, C.; Kazerani, I.; Doppler, K.; Thomas, D.; Gurke, R.; Sisignano, M.; Kalelkar, P. P.; Garcia, A.; Monje, P. V.; Nusrat, A.; Brack, A.; Krug, S. M.; Sommer, C.; Rittner, H.

10.1101/2024.08.04.605987 — neuroscience — Posted on 2024-08-06

4184 The interplay between motor cost and self-efficacy related to walking across terrain in gaze and walking decisions

da Eira Silva, V.; Marigold, D. S.

10.1101/2024.08.02.606420 — neuroscience — Posted on 2024-08-06

4185 Computational modeling of drug response identifies mutant-specific constraints for dosing panRAF and MEK inhibitors in melanoma

Goetz, A.; Shanahan, F.; Brooks, L.; Lin, E.; Mroue, R.; Dela Cruz, D.; Hunsaker, T.; Czech, B.; Dixit, P.; Segal, U.; Martin, S.; Foster, S. A.; Gerosa, L.

10.1101/2024.08.02.606432 — systems biology — Posted on 2024-08-06

4186 S2-PepAnalyst: A Web Tool for Predicting Plant Small Signalling Peptides

Vomo Donfack, K. L.; Abaach, M.; Luna, A. M.; Ginot, G.; Doblas, V. G.; Morilla, I.

10.1101/2024.08.02.606319 — plant biology — Posted on 2024-08-06

4187 Paradoxical SERCA dysregulation contributes to atrial fibrillation in a model of diet-induced obesity

Ponce-Balbuena, D.; Tyrrell, D.; Cruz-Cortes, C.; Guerrero-Serna, G.; Monteiro da Rocha, A.; Herron, T. J.; Song, J.; Raza, D.; Anumonwo, J.; Goldstein, D.; Espinoza-Fonseca, L. M.

10.1101/2024.08.02.606385 — physiology — Posted on 2024-08-06

4188 Peucedanol ameliorates LPS-induced inflammation in RAW264.7 cells and CLP-induced sepsis in mice by inhibiting TLR4/myD88/NF-κB pathway

Yao, Q.; Chang, T. B.

10.1101/2024.08.02.606445 — pharmacology and toxicology — Posted on 2024-08-06

4189 VSTM2L protects prostate cancer cells against ferroptosis via inhibiting VDAC1 oligomerization and maintaining mitochondria homeostasis

Yang, J.; Lu, X.; Hao, J.-L.; Li, L.; Ruan, Y.-T.; An, X.-N.; Dong, X.-M.; gao, p.

10.1101/2024.08.03.606470 — cancer biology — Posted on 2024-08-06

4190 Reproductive state controls transcription in the murine liver, with implications for breast cancer liver metastasis

Ozaki, M. K.; Zhang, Y.; Bartlett, A. Q.; De Wilde, E.; Guan, X.; Yang, A.; Xia, Z. K.; Schedin, P. J.

10.1101/2024.08.02.606434 — cancer biology — Posted on 2024-08-06

4191 Genomic evolution of pancreatic cancer at single-cell resolution

Zhang, H.; Sashittal, P.; Karnoub, E.-R.; Jakatdar, A.; Umeda, S.; Hong, J.; Noronha, A. M.; Cardenas, A.; Erakky, A.; McIntyre, C. A.; Hayashi, A.; Lecomte, N.; Park, W.; Pan, N.; O'Reilly, E. M.; Wei, A. C.; Raphael, B. J.; Iacobuzio-Donahue, C. A.

10.1101/2024.08.03.605165 — cancer biology — Posted on 2024-08-06

4192 OXPHOS TARGETING OF MYCN-AMPLIFIED NEUROBLASTOMA

Epp, S. C.; Egan, D.; Poon, E.; Abdul Aziz, A. A.; Wynne, K.; Halasz, M.; Kolch, W.

10.1101/2024.08.03.606365 — cancer biology — Posted on 2024-08-06

4193 Identification of robust RT-qPCR reference genes for studying changes in gene expression in response to hypoxia in breast cancer cell lines

Malcolm, J. R.; Bridge, K. S.; Holding, A. N.; Brackenbury, W. J.

10.1101/2024.08.02.606329 — cancer biology — Posted on 2024-08-06

4194 Comprehensive Guide of Epigenetics and Transcriptomics Data Quality Control

Comendul, A.; Ruf-zamojski, F.; Ford, C. T.; Agarwal, P.; Zaslavsky, E.; Nudleman, G.; Hariharan, M.; Rubenstein, A.; Nair, V. D.; Pincas, H.; Michaleas, A. M.; Sealfon, S. C.; Woods, C. W.; Claypool, K. T.; Jaimes, R.

10.1101/2024.08.02.606411 — bioinformatics — Posted on 2024-08-06

4195 scMitoMut for calling mitochondrial lineage related mutations in single cells

SUN, W.; van Ginneken, D.; Perie, L.

10.1101/2024.08.03.606286 — bioinformatics — Posted on 2024-08-06

4196 C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability

Nagarajan, S. K.; Weber, J.; Roderer, D.; Piontek, J.

10.1101/2024.08.02.605804 — bioinformatics — Posted on 2024-08-06

4197 GPSA2: combining landmark-free and landmark-based methods in geometric morphometrics

Pomidor, B. J.; Dean, M. D.

10.1101/2024.08.03.604701 — bioinformatics — Posted on 2024-08-06

4198 Localized in vivo prodrug activation using radionuclides

Quintana, J.; Jiang, F.; Kang, M.; Valladolid Onecha, V.; Konik, A.; Qin, L.; Rodriguez, V.; Hu, H.; Borges, N.; Khurana, I.; Banla, L. I.; Le Fur, M.; Caravan, P.; Schuemann, J.; Bertolet, A.; Weissleder, R.; Miller, M.; Ng, T.

10.1101/2024.08.02.606075 — bioengineering — Posted on 2024-08-06

4199 A Tough Biointerface in Human Knee Empowered by Dynamic Phase-transforming Minerals in Collagenous Matrix

Li, W.; Wang, X.; Mao, R.; Li, D.; Meng, H.; Zhang, R.; Fang, J.; Kang, Z.; Wu, B.; Ma, W.; Yao, X.; Xie, C.; Li, R.; Wang, J.; Chen, X.; Pan, X.; Chen, W.; Duan, W.; Gao, H.; Ouyang, H.

10.1101/2024.08.03.606023 — bioengineering — Posted on 2024-08-06

4200 Fallow deer approaching humans are also more likely to be seropositive for Toxoplasma gondii.

Ryan, A. R.; Zintl, A.; Griffin, L. L.; Quinn, M.; Haigh, A.; Sabbatini, P.; Amin, B.; Ciuti, S.

10.1101/2024.08.03.606274 — animal behavior and cognition — Posted on 2024-08-06

4201 Two distinct chromatin modules regulate proinflammatory gene expression

Seufert, I.; Gerosa, I.; Varamogianni-Mamatsi, V.; Vladimirova, A.; Sen, E.; Mantz, S.; Rademacher, A.; Schumacher, S.; Liakopoulos, P.; Kolovos, P.; Anders, S.; Mallm, J.-P.; Papantonis, A.; Rippe, K.

10.1101/2024.08.03.606159 — genomics — Posted on 2024-08-06

4202 High-throughput gene expression analysis with TempO-LINC sensitively resolves complex brain, lung and kidney heterogeneity at single-cell resolution

Eastburn, D. J.; White, K. S.; Jayne, N. D.; Camiolo, S.; Montis, G.; Ha, S.; Watson, K. G.; Yeakley, J. M.; McComb, J.; Seligmann, B.

10.1101/2024.08.03.606484 — genomics — Posted on 2024-08-06

4203 Six drivers of aging identified among genes differentially expressed with age

Coler-Reilly, A.; Pincus, Z.; Scheller, E. L.; Civitelli, R.

10.1101/2024.08.02.606402 — genetics — Posted on 2024-08-06

4204 Movement responses to lethal risk: an integrative analysis of proactive and reactive antipredator behaviours in a large herbivore

Vanderlocht, C.; Robira, B.; Corradini, A.; Dal Farra, S.; Ossi, F.; Righetti, D.; Hauffe, H. C.; Pedrotti, L.; Cagnacci, F.

10.1101/2024.08.03.606415 — ecology — Posted on 2024-08-06

4205 An Information Theory Framework for Movement Path Segmentation and Analysis

Sethi, V.; Spiegel, O.; Salter, R.; Cain, S.; Toledo, S.; Getz, W.

10.1101/2024.08.02.606194 — ecology — Posted on 2024-08-06

4206 ImPaqT - A Golden Gate-based Immunological Toolkit for Zebrafish Transgenesis

Hurst, S.; Dimmler, C.; Cronan, M.

10.1101/2024.08.02.606358 — immunology — Posted on 2024-08-06

4207 Dynamics of Bagaza, West Nile, and Usutu viruses in Portugal revealed by long-term serological surveillance in red-legged partridges, 2018-2022

Fontoura-Goncalves, C.; Llorente, F.; Perez-Ramirez, E.; Jimenez-Clavero, M. A.; Costa, J. B.; de Mello, G.; Goncalves, D.; Alves, P. C.; Hofle, U.; Queiros, J.

10.1101/2024.08.02.606292 — immunology — Posted on 2024-08-06

4208 Integration of immune cell-target cell conjugate dynamics changes the time scale of immune control of cancer

Yang, Q.; Traulsen, A.; Altrock, P. M.

10.1101/2024.08.02.606336 — immunology — Posted on 2024-08-06

4209 Cancer therapy via neoepitope-specific monoclonal antibody cocktails

Hartman, C. J.; Mohamed, A. O.; Shukla, G. S.; Pero, S. C.; Sun, Y.-J.; Rodriguez, R. S.; Genovese, N. F.; Kohler, N. M.; Hemphill, T. R.; Huang, Y. H.; Krag, D. N.; Ackerman, M. E.

10.1101/2024.08.02.606410 — immunology — Posted on 2024-08-06

4210 Integrated Single-Cell Multiomic Profiling of Caudate Nucleus Suggests Key Mechanisms in Alcohol Use Disorder

Green, N.; Gao, H.; Chu, X.; Yuan, Q.; McGuire, P.; Lai, D.; Jiang, G.; Xuei, X.; Reiter, J.; Stevens, J.; Sutherland, G.; Goate, A. M.; Pang, Z. P.; Slesinger, P.; Hart, R. P.; Tischfield, J. A.; Agrawal, A.; Wang, Y.; Duren, Z.; Edenberg, H.; Liu, Y.

10.1101/2024.08.02.606355 — neuroscience — Posted on 2024-08-06

4211 Generating Synthetic Task-based Brain Fingerprints for Population Neuroscience Using Deep Learning

Serin, E.; Ritter, K.; Schumann, G.; Banaschewski, T.; Marquand, A.; Walter, H.

10.1101/2024.08.03.606469 — neuroscience — Posted on 2024-08-06

4212 A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding

Goode, T. D.; Alipio, J. B.; Besnard, A.; Pathak, D.; Kritzer-Cheren, M.; Chung, A.; Duan, X.; Sahay, A.

10.1101/2024.08.02.606427 — neuroscience — Posted on 2024-08-06

4213 Cortical Complexity Alterations in Motor Subtypes of Parkinson's Disease: A Surface-Based Morphometry Analysis of Fractal Dimension

Dehghan, Y.; Sarbaz, Y.

10.1101/2024.08.03.606491 — neuroscience — Posted on 2024-08-06

4214 Understanding Electric Brain Stimulation Through the Reciprocity Theorem

Ness, T. V.; Koch, C.; Einevoll, G.

10.1101/2024.08.04.603691 — neuroscience — Posted on 2024-08-06

4215 Geometry representations along visual pathways in human spatial navigation

Zeng, T.; Cai, M. B.

10.1101/2024.08.04.605402 — neuroscience — Posted on 2024-08-06

4216 Constraint Induced Movement Therapy Confers only a Transient Behavioral Benefit but Enduring Functional Circuit-Level Changes after Experimental TBI.

Paydar, A.; Khorasani, L.; Harris, N. G.

10.1101/2024.08.02.606449 — neuroscience — Posted on 2024-08-06

4217 Bridging tuning and invariance with equivariant neuronal representations

Hoeller, J.; Zhong, L.; Pachitariu, M.; Romani, S.

10.1101/2024.08.02.606398 — neuroscience — Posted on 2024-08-06

4218 VR HMD color calibration and accurate control of emitted light using Three.js

Duay, K.; Mizokami, Y.; Nagai, T.

10.1101/2024.08.02.606304 — neuroscience — Posted on 2024-08-06

4219 Expanding the Distribution and Phylogenetic Insights of Chrysobrycon mojicai in the Peruvian Amazon: Morphological and Molecular Analyses with Taxonomic Corrections

Chuctaya, J.; Ruiz-Tafur, M.; Faustino-Fuster, D.; Meza-Vargas, V.; Garcia-Davila, C. R.; Castro-Ruiz, D.; Angulo, C.; Vanegas-Rios, J. A.

10.1101/2024.08.02.606444 — zoology — Posted on 2024-08-06

4220 The intrinsic dimension of gene expression during cell differentiation

Biondo, M.; Cirone, N.; Valle, F.; Lazzardi, S.; Caselle, M.; Osella, M.

10.1101/2024.08.02.606382 — systems biology — Posted on 2024-08-06

4221 The contrasting flowering-time among coffee genotypes is associated with ectopic and differential expressions of genes related to environment, floral development, and hormonal regulation

Lopez, M. E.; de Oliveira, R. R.; Azevedo, L. M.; Santos, I. S.; Ribeiro, T. H. C.; Zhang, D.; Chalfun-Junior, A.

10.1101/2024.08.02.605191 — plant biology — Posted on 2024-08-06

4222 Physiological and Molecular Responses of Projected Future Temperatures on Potato Tuberization

Guillemette, A.; Hernandez Casanova, G.; Hamilton, J. P.; Pokorna, E.; Dobrev, P. I.; Motyka, V.; Rashotte, A. M.; Leisner, C.

10.1101/2024.08.02.606361 — plant biology — Posted on 2024-08-06

4223 Two types of regeneration mechanism in acute liver injury

Aoyagi, T.; Goya, T.; Imoto, K.; Azuma, Y.; Hioki, T.; Kohjima, M.; Tanaka, M.; Oda, Y.; Ogawa, Y.

10.1101/2024.08.04.606468 — pathology — Posted on 2024-08-06

4224 A role for YAP-mediated regulation of invadopodia in HNSCC cells

Jerrell, R. J.; Marchlewski, D. D.; Parekh, A.

10.1101/2024.08.02.606435 — cancer biology — Posted on 2024-08-06

4225 Thrombo-inflammation analyzed in a validated seven-layer platelet decision model: cellular decisions are tough problems fast and heuristically solved

Prada Salcedo, J.; Balkenhol, J.; Osmanoglu, O.; Afshar, M.; Kaltdorf, M.; Hoffmann, S.; von Mammen, S.; Heinze, K.; Schulze, H.; Dandekar, T.

10.1101/2024.08.02.606324 — bioinformatics — Posted on 2024-08-06

4226 Expression quantitative trait locus mapping in recombinant gametes using single nucleus RNA sequencing

Parker, M. T.; Amar, S.; Campoy, J. A.; Krause, K.; Tusso, S.; Marek, M.; Huettel, B.; Schneeberger, K.

10.1101/2024.08.02.606310 — bioinformatics — Posted on 2024-08-06

4227 Expanding the scope of a catalogue search to bioisosteric fragment merges using a graph database approach

Wills, S.; Sanchez-Garcia, R.; Roughley, S. D.; Merritt, A.; Hubbard, R. E.; von Delft, F.; Deane, C. M.

10.1101/2024.08.02.606367 — bioinformatics — Posted on 2024-08-06

4228 BLEND: Probabilistic Cellular Deconvolution with Automated Reference Selection

Huang, P.; Cai, M.; McKennan, C.; Wang, J.

10.1101/2024.08.02.606458 — bioinformatics — Posted on 2024-08-06

4229 Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis

Chouaib, A. A.; Chang, H.-F.; Khamis, O. M.; Echeverry, S.; Demeersseman, L.; Elizarova, S.; Daniel, J. A.; Valitutti, S.; Barg, S.; Pape, C.; Shaib, A. H.; Becherer, U.

10.1101/2024.08.02.606323 — bioengineering — Posted on 2024-08-06

4230 Multiplex genome editing eliminates the Warburg Effect without impacting growth rate in mammalian cells

Hefzi, H.; Martinez-Monge, I.; Marin de Mas, I.; Cowie, N. L.; Gomez Toledo, A.; Noh, S. M.; Karottki, K. J. l. C.; Decker, M.; Arnsdorf, J.; Camacho-Zaragoza, J. M.; Kol, S.; Schoffelen, S.; Pristovsek, N.; Hansen, A. H.; Miguez, A. A.; Bjorn, S. P.; Broendum, K. J. l. C. K.; Javidi, E. M.; Jensen, K. L.; Stangl, L.; Kreidl, E.; Kallehauge, T. B.; Ley, D.; Menard, P.; Petersen, H. M.; Sukhova, Z.; Bauer, A.; Casanova, E.; Barron, N.; Malstrom, J.; Nielsen, L. K.; Lee, G. M.; Kildegaard, H. F.; Voldborg, B. G.; Lewis, N. E.

10.1101/2024.08.02.606284 — bioengineering — Posted on 2024-08-06

4231 Mechano-adaptation: Exercise-driven Piezo1 & Piezo2 augmentation and chondroprotection in articular cartilage

Jing, X.; Kotelsky, A.; Dirksen, R. T.; Sandeep, M.; Buckley, M.; Lee, W.

10.1101/2024.08.02.606183 — bioengineering — Posted on 2024-08-06

4232 Engineered human iPS cell models reveal altered podocytogenesis and glomerular capillary wall in CHD-associated SMAD2 mutations

Bhattacharya, R.; Ward, T.; Kalejaiye, T. D.; Mishra, A.; Leeman, S.; Azaghi, H.; Seidman, J. G.; Seidman, C. E.; Musah, S.

10.1101/2024.08.02.606108 — bioengineering — Posted on 2024-08-06

4233 SleepSatelightFTC: A Lightweight and Interpretable Deep Learning Model for Single-Channel EEG-Based Sleep Stage Classification

Ito, A.; Tanaka, T.

10.1101/2024.08.02.606301 — bioengineering — Posted on 2024-08-06

4234 Probabilistic modeling reveals coordinated social interaction states and their multisensory bases

Stednitz, S. J.; Lesak, A.; Fecker, A.; Painter, P.; Washbourne, P.; Mazzucato, L.; Scott, E. K.

10.1101/2024.08.02.606104 — animal behavior and cognition — Posted on 2024-08-06

4235 Differential Expression Analysis for Spatially Correlated Data

Vasconcelos, A. G.; McGuire, D.; Simon, N.; Danaher, P.; Shojaie, A.

10.1101/2024.08.02.606405 — genomics — Posted on 2024-08-06

4236 Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk

Mummey, H.; Elison, W.; Korgaonkar, K.; Elgamel, R.; Kudtarkar, P.; Griffin, E.; Benaglio, P.; Miller, M.; Jha, A.; Manning Fox, J. E.; Mccarthy, M.; Preissl, S.; Gloyn, A. L.; Macdonald, P. E.; Gaulton, K. J.

10.1101/2024.08.03.606460 — genomics — Posted on 2024-08-06

4237 Performance and Robustness of Parameter Estimation from Phylogenetic Trees Using Neural Networks

Qin, T.; van Benthem, K.; Valente, L.; Etienne, R.

10.1101/2024.08.02.606350 — evolutionary biology — Posted on 2024-08-06

4238 Diseases and invasive species have synergistic effects with other anthropogenic threats on the functional and phylogenetic diversity in Testudines and Crocodilia

Rodriguez-Caro, R. C.; Gumbs, R.; Gracia, E.; Blomberg, S. P.; Cayuela, H.; Grace, M. K.; Carmona, C. P.; Perez-Mendoza, H. A.; Gimenez, A.; Davis, K. J.; Salguero-Gomez, R.

10.1101/2024.08.02.606360 — ecology — Posted on 2024-08-06

4239 A high lipid diet leads to greater pathology and lower tolerance during infection

Perrine, W. G.; Sauer, E.; Love, A. C.; Morris, A. N.; Novotny, J.; DuRant, S.

10.1101/2024.08.02.606372 — ecology — Posted on 2024-08-06

4240 CHRONIC LUNG INFLAMMATION LEADS TO MYELOID SKEWING OF HEMATOPOIETIC STEM CELLS IN A CYSTIC FIBROSIS MOUSE MODEL

Braga, C. L.; Isler Mancuso, R.; Thompson, E. N.; Öz, H. H.; Gudneppanavar, R.; Zhang, P.-X.; Huang, P.; Murray, T.; Egan, M.; Krause, D. S.; Bruscia, E. M.

10.1101/2024.08.02.606400 — immunology — Posted on 2024-08-06

4241 Seeing or believing in hyperplexed spatial proteomics via antibodies. New and old biases for an image-based technology.

Bolognesi, M. M.; Dall'Olio, L.; Maerten, A.; Borghesi, S.; Castellani, G.; CATTORETTI, G.

10.1101/2024.08.02.606335 — systems biology — Posted on 2024-08-06

4242 Nutrient Challenges in a Changing Atmosphere: Investigating Biomass Growth and Mineral Concentration Changes in Soybean Plants under Elevated CO2

Kaur, R.; Durstock, M.; Prior, S. A.; Runion, B.; Ainsworth, E.; Baxter, I.; Sanz-Saez, A.; Leisner, C.

10.1101/2024.08.02.606357 — plant biology — Posted on 2024-08-06

4243 Knockout of the tomato HAIRY MERISTEM 4 alters phloem-characteristics and impairs development

Khedia, J.; Vishwakarma, A.; Galsurker, O.; Corem, S.; Gupta, S. K.; Arazi, T.

10.1101/2024.08.02.606343 — plant biology — Posted on 2024-08-06

4244 RF Channel-Based Adaptive Beamforming for 3D Ultrasound Localization Microscopy

Chabouh, G.; Pialot, B.; Denis, L.; Dumas, R.; Couture, O.; Muleki Seya, P.; Varray, F.

10.1101/2024.08.02.606290 — physiology — Posted on 2024-08-06

4245 Cleavage of the vascular matrix attracts glioblastoma cells to infiltrate the brain parenchyma

Perryman, L.; Hoye, A.; Cox, T. R.; Baker, A.-M.; Strobech, J.; Leonte, L.; Singh, L. B.; Popov, S.; Lorentzen, L. G.; Reuten, R.; Skovgaard Poulsen, H.; Davies, M. J.; Jones, C.; Erler, J. T.

10.1101/2024.08.02.606279 — cancer biology — Posted on 2024-08-06

4246 Plectin-mediated cytoskeletal crosstalk as a target for inhibition of hepatocellular carcinoma growth and metastasis.

Korelova, K.; Prechova, M.; Frick, L.; Sarnova, L.; Bisht, P.; Novotna, P.; Kosla, J.; Bortel, P.; Borutzki, Y.; Bileck, A.; Gerner, C.; Rahbari, M.; Rahbari, N.; Birgin, E.; Kvasnicova, B.; Galisova, A.; Sulkova, K.; Bauer, A.; Jobe, N.; Tolde, O.; Sticova, E.; Rosel, D.; O Connor, T.; Otahal, M.; Jirak, D.; Heikenwalder, M.; Wiche, G.; Meier-Menches, S. M.; Gregor, M.

10.1101/2024.08.02.606331 — cancer biology — Posted on 2024-08-06

4247 Lipidome visualisation, comparison, and analysis in a vector space

Olzhabaev, T.; Müller, L.; Krause, D.; Schwudke, D.; Torda, A. E.

10.1101/2024.08.02.606134 — bioinformatics — Posted on 2024-08-06

4248 iSODA: A Comprehensive Tool for Integrative Omics Data Analysis in Single- and Multi-Omics Experiments

Olivier-Jimenez, D.; Rico, D. J. E.; Harari, O.; Cruchaga, C.; Ali, M.; Ori, A.; Di Fraia, D.; Cabukusta, B.; Henrie, A.; Giera, M. A.; Mohammed, Y.

10.1101/2024.08.02.605811 — bioinformatics — Posted on 2024-08-06

4249 Newly developed structure-based methods do not outperform standard sequence-based methods for large-scale phylogenomics

Mutti, G.; Ocana-Pallares, E.; Gabaldon, T.

10.1101/2024.08.02.606352 — bioinformatics — Posted on 2024-08-06

4250 The genome assembly of Rhabditoides inermis from a complex microbial community reveals further evidence for parallel gene family expansions across multiple nematodes

Roedelsperger, C.; Roeseler, w.; Athanasouli, M.; Wighard, S.; Herrmann, M.; Sommer, R. J.

10.1101/2024.08.02.605984 — genomics — Posted on 2024-08-06

4251 Methodology for the identification and analysis of species associations in biological communities using statistical distributions

Seleznev, D. G.; Prokin, A. A.; Kurina, E. M.

10.1101/2024.08.02.606312 — ecology — Posted on 2024-08-06

4252 Sensitivities in associating land-system archetypes with sustainability metrics: Insights from simulations

Varma, V.; Evans, P. M.; Butikofer, L.; Goodwin, C. E.; Pywell, R. F.; Redhead, J. W.; Storkey, J.; Bullock, J. M.; Mead, A.

10.1101/2024.08.01.606212 — ecology — Posted on 2024-08-06

4253 LONG-TERM ECOLOGICAL MONITORING IN INDIA: A SYNTHESIS

Tiruvaimozhi, Y. V.; Borah, J.; Kala, C. P.; Kunte, K.; Patel, B.; Sreejith, K. A.; Thadani, R.; Osuri, A. M.; Ghosh-Harihar, M.

10.1101/2024.08.02.606338 — ecology — Posted on 2024-08-06

4254 Predicting reproductive phenology of wind-pollinated trees via PlanetScope time series

Song, Y.; Katz, D. S.; Zhu, Z.; Beaulieu, C.; Zhu, K.

10.1101/2024.08.02.606226 — ecology — Posted on 2024-08-06

4255 Heat Shock Factor Regulation of Antimicrobial Peptides Expression Suggests a Conserved Defense Mechanism Induced by Febrile Temperature in Arthropods

Xiao, B.; Chen, S.; Wang, Y.; Liao, X.; He, J.; Li, C.

10.1101/2024.08.02.606295 — immunology — Posted on 2024-08-06

4256 Minimally invasive activation of spared interneurons alleviates local CA1 hypersynchrony and behavioral deficits in a model of temporal lobe epilepsy

Matringhen, C.; Vigier, A.; Bourtouli, N.; Marissal, T.

10.1101/2024.08.02.606307 — neuroscience — Posted on 2024-08-06

4257 Temporal kinetics of brain state effects on visual perception

Schmid, P.; Klein, T.; Minakowski, P.; Sager, S.; Reichert, C.; Knight, R. T.; Duerschmid, S.

10.1101/2024.08.02.606289 — neuroscience — Posted on 2024-08-06

4258 Anodal tsDCS restores the structure and function of the disrupted proprioceptive Ia synapses on spinal motoneurons in the SOD1 G93A mouse model of ALS

Jankowiak, T.; Cholewinski, M.; Krysciak, K.; Krok, E.; Grycz, K.; Baczyk, M.

10.1101/2024.08.02.606278 — neuroscience — Posted on 2024-08-06

4259 Environmental and molecular noise buffering by the cyanobacterial clock in individual cells

Eremina, A.; Schwall, C.; Saez, T.; Witting, L.; Kohlheyer, D.; Martins, B. M. C.; Thomas, P.; Locke, J. C. W.

10.1101/2024.08.02.605997 — systems biology — Posted on 2024-08-06

4260 mosGraphGPT: a foundation model for multi-omic signaling graphs using generative AI

Zhang, H.; Huang, D.; Chen, E.; Cao, D.; Xu, T.; Dizdar, B.; Li, G.; Chen, Y.; Payne, P.; Province, M.; Li, F.

10.1101/2024.08.01.606222 — bioinformatics — Posted on 2024-08-06

4261 WITHDRAWN: Molecular Dynamics guided Brownian tomography of apoferritin in liquid water

Acosta-Gutierrez, S.; De Pace, C.; Ing, G.; Marchello, G.; Wilkinson, N.; Gervasio, F.; Ruiz-Perez, L.; Battaglia, G.

10.1101/2021.04.30.442083 — biophysics — Posted on 2024-08-06

4262 Evolution of apoptotic signalling pathways within lophotrochozoans

Horkan, H. R.; Popgeorgiev, N.; Vervoort, M.; Gazave, E.; Krasovec, G.

10.1101/2023.12.11.571055 — evolutionary biology — Posted on 2024-08-06

4263 Detecting branching rate heterogeneity in multifurcating trees with applications in lineage tracing data

Gao, Y.; Feder, A. F.

10.1101/2024.06.27.601073 — evolutionary biology — Posted on 2024-08-06

4264 The influence of the head model on magnetoencephalography-derived functional connectivity fingerprinting

Schelfhout, M.; Hinault, T. T.; Lago, S.; Arcara, G.; Amico, E.; Fraschini, M.; Marinazzo, D.

10.1101/2024.08.05.606621 — neuroscience — Posted on 2024-08-06

4265 Statistics in service of metascience: Measuring replication distance with reproducibility rate

Buzbas, E. O.; Devezer, B.

10.1101/2024.08.05.606644 — scientific communication and education — Posted on 2024-08-06

4266 Red blood cell-tumour cell interactions promote tumour cell progression

Pereira-Veiga, T.; Yanez-Gomez, C.; Pekkarinen, A.; Abuin, C.; Blechner, C.; Gonzalez-Conde, M.; Bauer, A. T.; Vidal-y-Sy, S.; Moustafa, A.; Siebels, B.; Davila-Ibanez, A. B.; Cabezas-Sainz, P.; Santos, M.; Sanchez, L.; Gorgulho, J.; Götze, J.; Meissner, K.; Cueva, J.; Palacios, P.; Cortegoso, A.; Curiel, T.; Rodriguez, C.; Carmona, M.; Peine, S.; Schmidt, M.; Heuer-Olewinski, N.; Reck, M.; Abdo, M.; Lopez-Lopez, R.; Windhorst, S.; Pantel, K.; Wikman, H.; Costa, C.

10.1101/2024.08.02.606121 — cancer biology — Posted on 2024-08-06

4267 Clonal evolutionary analysis reveals patterns of malignant transformation in pancreatic cancer from Intraductal Papillary Mucinous IPMN Neoplasms (IPMN)

10.1101/2024.08.02.606217 — cancer biology — Posted on 2024-08-06

4268 Myeloid-instructed CD14+CD4+ T cells within the tumor microenvironment are associated with TNFα signaling and prolonged survival in non-small cell lung cancer

Marceaux, C.; Yokote, K.; Gayevskiy, V.; Batey, D.; Tarasova, I.; Choux, L.; Riley, L.; Tubau, N.; Hywood, J.; Christie, M.; Antippa, P.; Speed, T. P.; Rogers, K. L.; Phipson, B.; Asselin-Labat, M.-L.

10.1101/2024.08.02.606259 — cancer biology — Posted on 2024-08-06

4269 The intrinsically disordered N-terminus of SUMO1 is an intramolecular inhibitor of SUMO1 interactions

Richter, S. M.; Jin, F.; Ritterhoff, T.; Fergin, A.; Maurer, E.; Frank, A.; Daube, M.; Hajnal, A.; Klevit, R. E.; Gräter, F.; Flotho, A.; Melchior, F.

10.1101/2024.01.04.574143 — biochemistry — Posted on 2024-08-06

4270 Genetic background affects the strength of crossover interference in house mice

Morgan, A. P.; Payseur, B. A.

10.1101/2024.05.28.596233 — genetics — Posted on 2024-08-06

4271 An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration

Marefati, M.; Fernandez-Vallone, V.; Leprovots, M.; Vasile, G.; Libert, F.; Lefort, A.; Dinsart, G.; Weber, A.; Jetzer, J.; Garcia, M.-I.; Vassart, G.

10.1101/2024.03.11.584399 — developmental biology — Posted on 2024-08-06

4272 Mfn2 induces NCLX-mediated calcium release from mitochondria.

Kolitsida, P.; Saha, A.; Caliri, A. W.; Assali, E.; Riera, A. M.; Itskanov, S.; Magana, C. S.; Stork, B.; Shirihai, O. S.; Sekler, I.; Koehler, C. M.; van der Bliek, A. M.

10.1101/2024.08.05.606704 — cell biology — Posted on 2024-08-06

4273 Apical Size Reduction by Macropinocytosis Alleviates Tissue Crowding

Bresteau, E.; Suva, E. E.; Revell, C.; Hassan, O. A.; Grata, A.; Sheridan, J.; Mitchell, J.; Arvantis, C.; Korobova, F.; Woolner, S.; Jensen, O. E.; Mitchell, B.

10.1101/2024.08.05.606662 — cell biology — Posted on 2024-08-06

4274 MiRNA-21-5p and MiRNA-125-5p Serve as Biomarkers for Diagnosis and Prognosis of Gastric Cancer

Zhang, X.; Xiang, Y.; Wang, J.

10.1101/2024.08.02.606443 — molecular biology — Posted on 2024-08-06

4275 High-intensity physiological activation disrupts the neural signatures of conflict processing

Avancini, C.; Ciria, L. F.; Alameda, C.; Palenciano, A. F.; Canales-Johnson, A.; Bekinschtein, T. A.; Sanabria, D.

10.1101/2023.07.31.550835 — neuroscience — Posted on 2024-08-06

4276 Evaluating permutation-based inference for partial least squares analysis of neuroimaging data

Danyluik, M.; Zeighami, Y.; Mukora, A.; Lepage, M.; Shah, J.; Joober, R.; Misic, B.; Iturria-Medina, Y.; Chakravarty, M.

10.1101/2024.08.02.606412 — neuroscience — Posted on 2024-08-06

4277 Effects of Aging, Fitness, and Cerebrovascular Status on White Matter Microstructural Health

Clements, G.; Camacho, P. B.; Bowie, D. C.; Low, K. A.; Sutton, B. P.; Gratton, G.; Fabiani, M.

10.1101/2024.08.04.606520 — neuroscience — Posted on 2024-08-06

4278 Multiscale heterogeneity of white matter morphometry in psychiatric disorders

Segal, A.; Smith, R. E.; Chopra, S.; Oldham, S.; Parkes, L.; Aquino, K. M.; Kia, S. M.; Wolfers, T.; Franke, B.; Hoogman, M.; Beckmann, C. F.; Westlye, L. T.; Andreassen, O. A.; Zaleskey, A.; Ben, H. J.; Davey, C. G.; Soriano-Mas, C.; Cardoner, N.; Tiego, J.; Yucel, M.; Braganza, L.; Suo, C.; Berk, M.; Cotton, S.; Bellgrove, M. A.; Marquand, A. F.; Fornito, A.

10.1101/2024.08.04.606523 — neuroscience — Posted on 2024-08-06

4279 A Framework to Identify Opportunities to Address Socioscientific Issues in the Elementary School Curricula: A Case Study from England, Italy, and Portugal

Pessoa, P.; de Lima, J.; Piacentini, V.; Realdon, G.; Jeffries, A.; Ometto, L.; Lopes, J. B.; Zeidler, D. L.; Fonseca, M. J.; Sousa, B.; Pinto, A.; Sa-Pinto, X.

10.1101/2024.08.02.606442 — scientific communication and education — Posted on 2024-08-06

4280 Comparative lifespan and healthspan of nonhuman primate species common to biomedical research

Huber, H. F.; Ainsworth, H. C.; Quillen, E. E.; Salmon, A.; Ross, C.; Azhar, A. D.; Bales, K.; Basso, M. A.; Coleman, K.; Colman, R.; Darusman, H. S.; Hopkins, B.; Hotchkiss, C. E.; Jorgensen, M. J.; Kavanagh, K.; Li, C.; Mattison, J. A.; Nathanielsz, P. W.; Saputro, S.; Scorpio, D. G.; Sosa, P.-M.; Vallender, E. J.; Wang, Y.; Zeiss, C. J.; Shively, C. A.; Cox, L. A.

10.1101/2024.07.31.606010 — physiology — Posted on 2024-08-06

4281 Predicting the Sequence-Dependent Backbone Dynamics of Intrinsically Disordered Proteins

Qin, S.; Zhou, H.-X.

10.1101/2023.02.02.526886 — biophysics — Posted on 2024-08-06

4282 GTalign: Spatial index-driven protein structure alignment, superposition, and search

Margelevicius, M.

10.1101/2023.12.18.572167 — bioinformatics — Posted on 2024-08-06

4283 Proteome-Wide Bioinformatic Annotation and Functional Validation of the Monotopic Phosphoglycosyl Transferase Superfamily

Durand, T.; Dodge, G. J.; Siuda, R. P.; Higinbotham, H. R.; Arbour, C. A.; Ghosh, S.; Allen, K. N.; Imperiali, B.

10.1101/2024.07.10.602977 — biochemistry — Posted on 2024-08-06

4284 Synthetic And Natural Face Identity Processing Share Common Mechanisms

Uittenhove, K.; Otroshi Shahreza, H.; Marcel, S.; Ramon, M.

10.1101/2024.08.03.605972 — animal behavior and cognition — Posted on 2024-08-06

4285 Genome-wide mapping of native co-localized G4s and R-loops in living cells

Liu, T.; Shen, X.; Ren, Y.; Lu, H.; Liu, Y.; Chen, C.; Yu, L.; Xue, Z.

10.1101/2024.06.03.597194 — genomics — Posted on 2024-08-06

4286 Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

Noh, M.; Che, X.; Jin, X.; Lee, D.-K.; Kim, H.-J.; Park, D. R.; Lee, S. Y.; Lee, H.; Gardella, T. J.; Choi, J.-Y.; Lee, S.

10.1101/2024.03.13.584815 — genomics — Posted on 2024-08-06

4287 Non-linear transcriptional responses to gradual modulation of transcription factor dosage

Domingo, J.; Minaeva, M.; Morris, J. A.; Ghatan, S.; Ziosi, M.; Sanjana, N. E.; Lappalainen, T.

10.1101/2024.03.01.582837 — genomics — Posted on 2024-08-06

4288 Transcriptomic profiling of Schlemm's canal cells reveals a lymphatic-biased identity and three major cell states

Balasubramanian, R.; Kizhatil, K.; Li, T.; Tolman, N.; Bhandari, A.; Clark, G.; Bupp-Chickering, V.; Kelly, R. A.; Zhou, S.; Peregrin, J.; Simon, M.; Montgomery, C.; Stamer, W. D.; Qian, J.; John, S.

10.1101/2023.08.31.555823 — genomics — Posted on 2024-08-06

4289 Interpreting SNP heritability in admixed populations

Huang, J.; Kleman, N.; Basu, S.; Shriver, M. D.; Zaidi, A. A.

10.1101/2023.08.04.551959 — genetics — Posted on 2024-08-06

4290 Variant-to-function dissection of rare non-coding GWAS loci with high impact on blood traits

Tardaguila, M.; Von Schiller, D.; Colombo, M.; Gori, I.; Coomber, E. L.; Vanderstichele, T.; Benaglio, P.; Chiereghin, C.; Gerety, S. S.; Vuckovic, D.; Landini, A.; Clerici, G.; Albers, P. K.; Ray-Jones, H.; Burnham, K. L.; Tokolyi, A.; Persyn, E.; Spivakov, M.; Sankaran, V. G.; Walter, K.; Kundu, K.; Pirastu, N.; Inouye, M.; Paul, D. S.; Davenport, E.; Sahlen, P.; Watt, S.; Soranzo, N.

10.1101/2024.08.05.606572 — genetics — Posted on 2024-08-06

4291 Context effects on repair of 5'-overhang DSB induced by Cas12a in Arabidopsis.

Lageix, S.; Hernandez Sanchez-Rebato, M.; Gallego, M. E.; Verbeke, J.; Bidet, Y.; Viala, S.; White, C. I.

10.1101/2024.08.05.606594 — genetics — Posted on 2024-08-06

4292 Phylogenetic analysis reveals how selection and mutation shape the coevolution of mRNA and protein abundances

Cope, A. L.; Schraiber, J. G.; Pennell, M.

10.1101/2024.07.08.602411 — evolutionary biology — Posted on 2024-08-06

4293 Substantial hierarchical reductions of genetic and morphological traits in the evolution of rotiferan parasites

Herlyn, H.; Hembrom, A. A.; Tosar, J. P.; Mauer, K. M.; Schmidt, H.; Dezfuli, B. S.; Hankeln, T.; Bachmann, L.; Sarkies, P.; Peterson, K. J.; Fromm, B.

10.1101/2024.08.01.605096 — evolutionary biology — Posted on 2024-08-06

4294 Adaptation of the eyes of grass puffer (Takifugu niphobles) to the riverine and marine environments

Osada, M.; Terai, Y.

10.1101/2022.04.28.489969 — evolutionary biology — Posted on 2024-08-06

4295 Pregnancy Reduces Il33+ Hybrid Progenitor Accumulation in the Aged Mammary Gland

Olander, A.; Ramirez, C.; Haro-Acosta, V.; Medina, P.; Kaushik, S.; Jonsson, V. D.; Sikandar, S. S.

10.1101/2024.08.01.606240 — developmental biology — Posted on 2024-08-06

4296 A spatial atlas of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress

Begeman, A.; Smolka, J. A.; Shami, A.; Waingankar, T. P.; Lewis, S. C.

10.1101/2024.08.05.604215 — cell biology — Posted on 2024-08-06

4297 The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

Hama, Y.; Fujioka, Y.; Yamamoto, H.; Mizushima, N.; Noda, N. N.

10.1101/2024.08.02.606296 — cell biology — Posted on 2024-08-06

4298 Image Correlation Spectroscopy is a Robust Tool to Quantify Cellular DNA Damage Response

Gopal, A.; Fernandez, B.; Wiseman, P. W.; Dubach, M.

10.1101/2024.08.05.606697 — cell biology — Posted on 2024-08-06

4299 Identification of bacteria involved in non-sulfate based hydrogen sulfide production in an aquaculture environment

Nguyen-tiet, A. M.; Puente-Sanchez, F.; Bertilsson, S.; Aalto, S. L.

10.1101/2024.04.12.589155 — microbiology — Posted on 2024-08-06

4300 Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen Cryptococcus neoformans

Billmyre, R. B.; Craig, C.; Lyon, J. W.; Reichardt, C.; Eickbush, M. T.; Zanders, S. E.

10.1101/2024.07.28.605507 — microbiology — Posted on 2024-08-06

4301 Disentangling acute motor deficits and adaptive responses evoked by the loss of cerebellar output

Sinha, N.; Israely, S.; Ben Harosh, O.; Harel, R.; Dewald, J.; Prut, Y.

10.1101/2024.05.21.595172 — neuroscience — Posted on 2024-08-06

4302 Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts

Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.; for the Alzheimer's Disease Neuroimaging Initiative,

10.1101/2024.08.05.606560 — neuroscience — Posted on 2024-08-06

4303 Individual alpha frequency tACS reduces functional connectivity across the default mode network

Carrasco-Gomez, M.; Cabrera-Alvarez, J.; Garcia-Colomo, A.; del Cerro-Leon, A.; Gomez-Ariza, C. J.; Santos, A.; Maestu, F.

10.1101/2024.08.04.606325 — neuroscience — Posted on 2024-08-06

4304 Impact of Blended NPSB Fertilizer Rates on Sugarcane (Saccharum officinarum L.) Varieties: Seed Cane Yield and Quality Insights from North Western Ethiopia

Ali, S.; Belay, B.; Abate, M.

10.1101/2024.08.02.606441 — plant biology — Posted on 2024-08-06

4305 Targeted anticancer pre-vinylsulfone covalent inhibitors of carbonic anhydrase IX

Vaskevicius, A.; Baronas, D.; Leitans, J.; Kvietkauskaite, A.; Ruksenaite, A.; Manakova, E.; Toleikis, Z.; Kaupinis, A.; Kazaks, A.; Gedgaudas, M.; Mickeviciute, A.; Juozapaitiene, V.; Schioth, H.; Jaudzems, K.; Valius, M.; Tars, K.; Grazulis, S.; Meyer-Almes, F.-J.; Matuliene, J.; Zubriene, A.; Dudutiene, V.; Matulis, D.

10.1101/2024.05.20.594908 — biophysics — Posted on 2024-08-06

4306 PUFA stabilizes a conductive state of the selectivity filter in IKs channels

Golluscio, A.; Eldstrom, J.; Jowais, J. J.; Perez, M. E.; Cunningham, K. P.; de La Cruz, A.; Wu, X.; Fedida, D.; Larsson, P.; Tieleman, D. P.; Corradi, V.

10.1101/2024.01.11.575247 — biophysics — Posted on 2024-08-06

4307 Interpretable single-cell factor decomposition using sciRED

Pouyabahar, D.; Andrews, T.; Bader, G.

10.1101/2024.08.01.605536 — bioinformatics — Posted on 2024-08-06

4308 Polarization gratings aided common-path Hilbert holotomography for high-throughput lipid droplets content assay

Zdankowski, P.; Winnik, J.; Rogalski, M.; Marzejon, M. J.; Wdowiak, E.; Dudka, W.; Jozwik, M.; Trusiak, M.

10.1101/2024.06.14.598984 — bioengineering — Posted on 2024-08-06

4309 Enzymatic carbon-fluorine bond cleavage by human gut microbes

Probst, S. I.; Felder, F. D.; Poltorak, V.; Mewalal, R.; Blaby, I. K.; Robinson, S. L.

10.1101/2024.07.15.601322 — biochemistry — Posted on 2024-08-06

4310 Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms

Moscona, R.; Wagner, T.; Geva, M.; Bucris, E.; Erster, O.; Zuckerman, N.; Mor, O.

10.1101/2024.08.04.606545 — molecular biology — Posted on 2024-08-06

4311 Post-replicative lesion processing limits DNA damage-induced mutagenesis

Maslowska, K. H.; Wong, R. P.; Ulrich, H. D.; Pages, V.

10.1101/2023.09.04.556208 — molecular biology — Posted on 2024-08-06

4312 PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription

Love, L.; Jutte, B. B.; Lindqvist, B.; Rhodjess, H.; Kieri, O.; Nowak, P.; Svensson, J. P.

10.1101/2024.03.17.583304 — microbiology — Posted on 2024-08-06

4313 Head down tilt 15° increases cerebral perfusion before recanalization in acute ischemic stroke: a pre-clinical MRI study.

Beretta, S.; Carone, D.; Cho, T.-H.; Vigano, M.; Diamanti, S.; Mariani, J.; Pedrazzini, F. A.; Bianchi, E.; Pini, C.; Bolbos, R.; Wiart, M.; Ferrarese, C.; Chauveau, F.

10.1101/2024.08.02.606281 — neuroscience — Posted on 2024-08-06

4314 Ih Block Reveals Separation of Timescales in Pyloric Rhythm Response to Temperature Changes in Cancer borealis

Schapiro, K.; Rittenberg, J.; Kenngott, M.; Marder, E.

10.1101/2024.05.04.592541 — neuroscience — Posted on 2024-08-06

4315 Understanding the Sport Viewership Experience using Functional Near-Infrared Spectroscopy

Potwarka, L.; Safati, A.; Pappas, A.; Ramchandani, G.; Narraine, M.; Gurbez, N.; Hall, P.

10.1101/2024.08.01.606260 — neuroscience — Posted on 2024-08-06

4316 DeepResBat: deep residual batch harmonization accounting for covariate distribution differences

An, L.; Zhang, C.; Wulan, N.; Zhang, S.; Chen, P.; Ji, F.; Ng, K. K.; Chen, C.; Zhou, J. H.; Yeo, B. T. T.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle Study of Aging,

10.1101/2024.01.18.574145 — neuroscience — Posted on 2024-08-06

4317 Multivalent Targeting of Blood-Brain Barrier LRP1 for Neurovascular Recovery Therapy for Alzheimer s Disease

Chen, J.; Pan, X.; Duro Castano, A.; Cai, H.; Guo, B.; Liu, X.; Yu, Y.; Lui, S.; Luo, K.; Ke, B.; Ruiz-Perez, L.; Wei, X.; Gong, Q.; Tian, X.; Battaglia, G.

10.1101/2024.05.06.592767 — neuroscience — Posted on 2024-08-06

4318 Micron-resolution fiber mapping in histology independent of sample preparation

Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.

10.1101/2024.03.26.586745 — pathology — Posted on 2024-08-06

4319 Feeding Rates of Sessile versus Motile Ciliates are Hydrodynamically Equivalent

Liu, J.; Man, Y.; Costello, J.; Kanso, E.

10.1101/2024.05.15.593824 — biophysics — Posted on 2024-08-06

4320 Robust virtual staining of landmark organelles

Liu, Z.; Hirata Miyasaki, E.; Pradeep, S.; Rahm, J. V.; Foley, C.; Chandler, T.; Ivanov, I. E.; Woosley, H. O.; Lao, T.; Balasubramanian, A.; Marreiros, R.; Liu, C.; Leonetti, M. D.; Aviner, R.; Arias, C.; Jacobo, A.; Mehta, S. B.

10.1101/2024.05.31.596901 — bioinformatics — Posted on 2024-08-06

4321 Dual-color micro-LEDs integrated neural interface for multi-control optogenetic electrophysiology

Ko, E.; Voroslakos, M.; Buzsaki, G.; Yoon, E.

10.1101/2024.07.30.605927 — bioengineering — Posted on 2024-08-06

4322 Low-Cost Robotic Manipulation of Live Microtissues for Cancer Drug Testing

Stepanov, I.; Gottshall, N. R.; Ahmadianyazdi, A.; Sinha, D.; Lockhart, E.; Nguyen, T. N.; Hassan, S.; Horowitz, L.; Yeung, R.; Gujral, T. S.; Folch, A.

10.1101/2024.03.21.586169 — bioengineering — Posted on 2024-08-06

4323 Plasmid2MC: Efficient cell-free recombination of plasmids into high-purity minicircle DNA for use in genome editing applications

Oliynyk, R. T.; Mahas, A.; Karpinski, E.; Church, G. M.

10.1101/2024.07.08.602524 — genomics — Posted on 2024-08-06

4324 What is the correct genomic structure of the complex chromosomal rearrangement at the Fm locus in Silkie chicken?

Sharma, A.; Vijay, N.

10.1101/2024.02.05.578760 — genomics — Posted on 2024-08-06

4325 Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation

Liu, H.; Binoy, A.; Ren, S.; Martino, T. C.; Miller, A. E.; Willis, C. R.; Veerabhadraiah, S. R.; Sukul, A.; Bons, J.; Rose, J.; Schilling, B.; Jurynec, M. J.; Zhu, S.

10.1101/2024.07.23.604872 — cell biology — Posted on 2024-08-06

4326 Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells

Koike, S.; Tachikawa, M.; Tsutsumi, M.; Okada, T.; Nemoto, T.; Keino-Masu, K.; Masu, M.

10.1101/2023.12.17.572077 — cell biology — Posted on 2024-08-06

4327 A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant

Lawrence, G. J.

10.1101/2024.07.01.601607 — molecular biology — Posted on 2024-08-06

4328 Tuberculosis susceptibility in genetically diverse mice reveals functional diversity of neutrophils

Ravesloot-Chavez, M. M.; Van Dis, E.; Fox, D.; Anaya-Sanchez, A.; Espich, S.; Nguyenla, X. H.; Rawal, S. L.; Samani, H.; Ballinger, M. A.; Thomas, H.; Kotov, D. I.; Vance, R.; Nachman, M.; Stanley, S.

10.1101/2023.06.29.547125 — immunology — Posted on 2024-08-06

4329 Mapping patterns of thought onto brain activity during movie-watching

Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.

10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-08-06

4330 The polyadenylation landscape after in vivo long-term potentiation in the rat brain

Guminska, N.; Pauzin, F. P.; Kuzniewska, B.; Miłek, J.; Wardaszka, P.; Krawczyk, P. S.; Mroczek, S.; Jelen, S.; Pagenhart, P. U.; Bramham, C. R.; Dziembowska, M.; Dziembowski, A.

10.1101/2024.06.05.597605 — neuroscience — Posted on 2024-08-06

4331 The visuomotor transformations underlying target-directed behavior

Zhao, P.; Tong, Y.; Lazarte, I. P.; Khan, B.; Tian, G.; Chen, K. K. Y.; Lam, T. K. C.; Semmelhack, J. L.

10.1101/2024.05.07.592863 — neuroscience — Posted on 2024-08-06

4332 Unpacking Unstructured Data: A Pilot Study on Extracting Insights from Neuropathological Reports of Parkinson's Disease Patients using Large Language Models

Stroganov, O.; Schedlbauer, A.; Lorenzen, E.; Kadhim, A.; Lobanova, A.; Lewis, D. A.; Glausier, J. R.

10.1101/2023.09.12.557252 — pathology — Posted on 2024-08-06

4333 Buzz Pollination: Investigations of Pollen Expulsion using the Discrete Element Method

Boucher-Bergstedt, C. G.; Jankauski, M. A.; Johnson, E.

10.1101/2024.08.01.606085 — biophysics — Posted on 2024-08-06

4334 CRISPR RNA binding drives structural ordering that primes Cas7-11 for target cleavage

Lin, C. P.; Li, H.; Brogan, D. J.; Wang, T.; Akbari, O. S.; Komives, E. A.

10.1101/2024.08.01.606276 — biophysics — Posted on 2024-08-06

4335 Perpetual bioplastic production by a cyanobacteria-dominated microbiome

Altamira, B.; Arnau Roca, M.; Lage, A.; Gonzalez-Flo, E.; Garcia, J.

10.1101/2023.11.06.565755 — bioengineering — Posted on 2024-08-06

4336 Novel Amplicons based Method for Near-Full-Length Genome (NFLG) Sequencing of HIV-1 Group M Recombinant Forms

Moscona, R.; Wagner1, T.; Geva, M.; Bucris, E.; Erster, O.; Zuckerman, N.; Mor, O.

10.1101/2024.08.04.606545 — molecular biology — Posted on 2024-08-06

4337 Qing-Luo-Yin eases angiogenesis in adjuvant-induced arthritis rats by activating PPARγ

zuo, j.; Yang, Z.

10.1101/2024.08.01.606254 — pharmacology and toxicology — Posted on 2024-08-06

4338 MRI-based quantification of cardiac-driven brain biomechanics for early detection of neurological disorders

Diorio, T.; Abderezaei, J.; Nauman, E. A.; Kurt, M.; Tong, Y.; Rayz, V. L.

10.1101/2024.08.01.606246 — bioengineering — Posted on 2024-08-06

4339 Compatibility of time-lapse dry incubator on in vitro production of bovine embryos

Tsuji, H.; Nagai, H.; Kobinata, S.; Koyama, H.; Khurchabilig, A.; Fukunaga, N.; Asada, Y.; Sugimura, S.

10.1101/2024.08.01.606272 — developmental biology — Posted on 2024-08-06

4340 Transmission of Mixed Convergent Signals at the Mouse Retinogeniculate Synapse

Sonoda, T.; Jiang, Q.; Acaron Ledesma, H.; Wei, W.; Chen, C.

10.1101/2024.08.01.606255 — neuroscience — Posted on 2024-08-06

4341 Sex-specific behavioral and thalamo-accumbal circuit adaptations after oxycodone abstinence.

Alonso-Caraballo, Y.; Li, Y.; Constantino, N. J.; Neal, M. A.; Driscoll, G. S.; Mavrikaki, M.; Bolshakov, V. Y.; Chartoff, E. H.

10.1101/2024.08.01.605459 — neuroscience — Posted on 2024-08-06

4342 Model selection for spectral parameterization

Wilson, L. E.; da Silva Castanheira, J.; Kinder, B. L.; Baillet, S.

10.1101/2024.08.01.606216 — neuroscience — Posted on 2024-08-06

4343 mosGraphFlow: a novel integrative graph AI model mining disease targets from multi-omic data

Zhang, H.; Cao, D.; Xu, T.; Chen, E.; Li, G.; Chen, Y.; Payne, P.; Province, M.; Li, F.

10.1101/2024.08.01.606219 — bioinformatics — Posted on 2024-08-06

4344 The transcription factor Chronophage/BCL11A/B promotes intestinal stem cell proliferation and endocrine differentiation in the Drosophila intestine

King, E. A.; Jacobsen, E.; Woolner, N.; de Navascues, J.; Marshall, O. J.; Korzelius, J.

10.1101/2024.08.05.606739 — developmental biology — Posted on 2024-08-06

4345 PDK-1/S6K and mTORC1 bypass systemic growth restrictions to promote regeneration

Maya, A. V.; Nogay, L.; Heckmann, L.; Grass, I.; Kierdorf, K.; Buescher, J.; Classen, A.-K.

10.1101/2024.08.05.606658 — developmental biology — Posted on 2024-08-06

4346 Exact distributions of threshold crossing times of proteins under post-transcriptional regulation by small RNAs

Ali, S. Y.; Prasad, A.; Das, D.

10.1101/2024.08.05.606600 — biophysics — Posted on 2024-08-06

4347 Enforced specificity of an animal symbiosis

Wagner, J. M.; Wong, J. H.; Millar, J. G.; Haxhimali, E.; Bruckner, A.; Naragon, T. H.; Boedicker, J. Q.; Parker, J.

10.1101/2024.08.04.606548 — evolutionary biology — Posted on 2024-08-06

4348 Molecular hydrogen can minimize negative effects of heat stress on the hard coral genus Acropora

Ostendarp, M.; de Breuyn, M.; El-Khaled, Y. C.; Garcias-Bonet, N.; Carvalho, S.; Peixoto, R. S.; Wild, C.

10.1101/2024.08.02.606431 — ecology — Posted on 2024-08-06

4349 A comprehensive atlas of testicular interstitium reveals Cd34+/Sox4+ mesenchymal cells as potential Leydig cell progenitors

Huang, X.; Xia, K. X.; Yang, M.; Hong, M. X.; Jiang, M. X.; Li, W.; Lei, Z.; Peng Xiang, A.; Zhao, W.

10.1101/2024.08.02.606288 — developmental biology — Posted on 2024-08-06

4350 Two structurally mobile regions control the conformation and function of metamorphic meiotic HORMAD proteins

Barroso, C.; Prince, J. P.; Rattu, P.; Kounde, D.; Ferrandiz, N.; Khalid, S.; Martinez-Perez, E.

10.1101/2024.08.05.606648 — molecular biology — Posted on 2024-08-05

4351 Magnitude processing and integration entail perceptual processes independent from the task

Togoli, I.; Collignon, O.; Bueti, D.; Fornaciai, M.

10.1101/2024.04.29.591641 — neuroscience — Posted on 2024-08-06

4352 Dorsomedial Striatum CB1R signaling is required for Pavlovian outcome devaluation in male Long Evans rats and reduces inhibitory synaptic transmission in both sexes

Stapf, C. A.; Keefer, S. E.; McInerney, J. M.; Cheer, J.; Calu, D. J.

10.1101/2024.05.01.592059 — neuroscience — Posted on 2024-08-06

4353 A non-conducting role of the Cav1.4 Ca2+ channel drives homeostatic plasticity at the cone photoreceptor synapse

Maddox, W.; Ordemann, G. J.; de la Rosa Vazquez, J.; Huang, A.; Gault, C.; Wisner, S. R.; Randall, K.; Futagi, D.; Salem, N. A.; Mayfield, R. D.; Zemelman, B. V.; DeVries, S.; Hoon, M.; Lee, A.

10.1101/2023.12.05.570129 — neuroscience — Posted on 2024-08-06

4354 Learning directed acyclic graphs for ligands and receptors based on spatially resolved transcriptomic analysis of ovarian cancer

Chowdhury, S.; Borgogno, S. F.; Calinawan, A. P.; Yang, P.; Wang, W.; Peng, J.; Mok, S.; Wang, P.

10.1101/2021.08.03.454931 — systems biology — Posted on 2024-08-06

4355 Silver Armor Against Bacteria: A Battle of Antimicrobial Effectiveness

Zaidi, A.

10.1101/2024.08.03.606483 — plant biology — Posted on 2024-08-06

4356 MicroCT-based imaging of microvasculature within bone and peri-implant tissues

Haberthür, D.; Khoma, O.-Z.; Hoessly, T.; Zoni, E.; Kruithof-de Julio, M.; Ryan, S. D.; Grunewald, M.; Bellon, B.; Sandgren, R.; Pippenger, B. E.; Bosshardt, D.; Djonov, V.; Hlushchuk, R.

10.1101/2023.03.08.531678 — physiology — Posted on 2024-08-06

4357 Design and Biophysical Characterization of Second-Generation Cyclic Peptide LAG-3 Inhibitors for Cancer Immunotherapy

Calvo-Barreiro, L.; Zhang, L.; Ali, Y.; Rehman, A. U.; Gabr, M.

10.1101/2024.08.04.606540 — pharmacology and toxicology — Posted on 2024-08-06

4358 Cryo-EM phase-plate images reveal unexpected levels of apparent specimen damage

Remis, J.; Petrov, P. N.; Zhang, J. T.; Axelrod, J. J.; Cheng, H.; Sandhaus, S.; Mueller, H.; Glaeser, R. M.

10.1101/2024.08.04.606536 — biophysics — Posted on 2024-08-06

4359 Snapshots of acetyl-CoA synthesis, the final step of CO2 fixation in the Wood-Ljungdahl pathway

Yin, M. D.; Lemaire, O. N.; Rosas-Jimenez, J. G.; Belhamri, M.; Shevchenko, A.; Hummer, G.; Wagner, T.; Murphy, B. J.

10.1101/2024.08.05.606187 — biophysics — Posted on 2024-08-06

4360 Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease

Hall, P.-R.; Jouen-Tachoire, T.; Schewe, M.; Proks, P.; Baukrowitz, T.; Carpenter, E. P.; Newstead, S.; Rodstrom, K.; Tucker, S. J.

10.1101/2024.08.05.606641 — biophysics — Posted on 2024-08-06

4361 Importance of updated benchmark sets for statistically correct AlphaFold applications

Dobson, L.; Tusnady, G. E.; Tompa, P.

10.1101/2024.08.02.606297 — bioinformatics — Posted on 2024-08-06

4362 Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders

Osbourne, R.; Thayer, K. M.

10.1101/2024.08.05.606567 — bioinformatics — Posted on 2024-08-06

4363 Enhanced Cell Wall Mechanics in VirtualLeaf Enable Realistic Simulations of Plant Tissue Dynamics

Grosseholz, R.; van Nieuwenhoven, R. W.; Mele, B. H.; Merks, R. M. H.

10.1101/2024.08.01.605200 — bioinformatics — Posted on 2024-08-06

4364 Dorsoventral comparison of intraspecific polymorphisms in the butterfly wing pattern using a convolutional neural network

Amino, K.; Hirakawa, T.; Yago, M.; Matsuo, T.

10.1101/2024.08.01.606114 — bioinformatics — Posted on 2024-08-06

4365 Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy

Pakharukova, N.; Thomas, B. N.; Bansia, H.; Li, L.; Abzalimov, R. R.; Kim, J.; Kahsai, A. W.; Pani, B.; Bassford, D. K.; Liu, S.; Zhang, X.; des Georges, A.; Lefkowitz, R. J.

10.1101/2024.07.31.605623 — biochemistry — Posted on 2024-08-06

4366 Octopus can use odor plumes to find food

Weertman, W. L.; Gopal, V.; Sivitilli, D. M.; Scheel, D.; Gire, D. H.

10.1101/2024.08.02.606436 — animal behavior and cognition — Posted on 2024-08-06

4367 Assessing nest sites, survival rates and population dynamics of free-living honeybee colonies in Germany: A comparative study using personally collected and Citizen Science data

Rutschmann, B.; Remter, F.; Roth, S.

10.1101/2024.08.02.606354 — ecology — Posted on 2024-08-06

4368 A flexible model for thermal performance curves

Cruz-Loya, M.; Mordecai, E. A.; Savage, V. M.

10.1101/2024.08.01.605695 — ecology — Posted on 2024-08-06

4369 Chemically induced dislocation and mutation of essential cytoskeletal proteins: A case study focusing on Coronin-A

Stange, M. B.; Grossmann, R.; Flemming, S.; Grebe, M.; Beta, C.

10.1101/2024.08.05.606068 — cell biology — Posted on 2024-08-05

4370 C-COMPASS: A Neural Network Tool for Multi-Omic Classification of Cell Compartments

Haas, D. T.; Trautmann, E. M.; Mao, X.; Gerl, M.; Klose, C.; Cheng, X.; Hasenauer, J.; Krahmer, N.

10.1101/2024.08.05.606647 — cell biology — Posted on 2024-08-05

4371 Active control of mitochondrial network morphology by metabolism driven redox state

Singh, G.; Vengayil, V.; Khannaa, A.; Adhikary, S.; Laxman, S.

10.1101/2024.08.05.606562 — cell biology — Posted on 2024-08-05

4372 The molecular basis of lamin-specific chromatin interactions

Wang, B.; Kronenberg-Tenga, R.; Rosti, V.; Di Patrizio Soldateschi, E.; Luo, Q.; Pinet, L.; Eibauer, M.; Boujemaa-Paterski, R.; Schuler, B.; Lanzuolo, C.; Medalia, O.

10.1101/2024.08.05.604734 — cell biology — Posted on 2024-08-05

4373 Crossovers are regulated by a conserved and disordered synaptonemal complex domain

Rodrigues Neves, A. R.; Cavka, I.; Rausch, T.; Koehler, S.

10.1101/2024.08.05.605830 — cell biology — Posted on 2024-08-05

4374 Tet2 loss suppress α-synuclein pathology by stimulating ciliogenesis

Quansah, E.; Vatsa, N.; Ensink, E.; Brown, J.; Cave, T.; Aguileta, M.; Kuhn, E.; Lindquist, A.; Gilliland, C.; Steiner, J. A.; Escobar Gavis, M. L.; Milciute, M.; Henderson, M.; Brundin, P.; Brundin, L.; Marshall, L. L.; Gordevicius, J.

10.1101/2024.08.02.606408 — neuroscience — Posted on 2024-08-06

4375 HIF-1 activated by PIM1 assembles a pathological transcription complex and regulon that drives JAK2V617F MPN disease

Kealy, D.; Ellerington, R.; Bansal, S.; Zeng, A. G. X.; Medeiros, J. J. F.; West, K. A.; Blacknell, N.-M.; Hawley, C. A.; Lukaszonek, J.; Gawne, R.; Khoo, H. M.; Caalim, G.; Drylie, B.; Chatzigerou, J.; Rodriguez Lima Ferreira, B.; Wang, G.; Fielding, A. K.; Kent, D.; Psaila, B.; Wilkinson, A. C.; Holding, A. N.; Hitchcock, I. S.; Mason, A. S.; Gupta, V.; Dick, J.; Bridge, K. S.

10.1101/2024.07.02.601518 — cancer biology — Posted on 2024-08-06

4376 DNA spontaneously wrapping around a histone core prefers negative supercoiling: A Brownian dynamics study

Long, C.; Liang, H.; Wan, B.

10.1101/2024.08.05.606726 — biophysics — Posted on 2024-08-06

4377 The Diffusion Exchange Ratio (DEXR): A minimal sampling of diffusion exchange spectroscopy to probe exchange, restriction, and time-dependence

Cai, T. X.; Williamson, N. H.; Ravin, R.; Basser, P.

10.1101/2024.08.05.606620 — biophysics — Posted on 2024-08-06

4378 Is tumor mutational burden predictive of response to immunotherapy?

Gurjao, C.; Tsukrov, D.; Imakaev, M.; Luquette, L. J.; Mirny, L. A.

10.1101/2020.09.03.260265 — genomics — Posted on 2024-08-06

4379 Evaluation of vectors for gene expression in Pseudovibrio bacteria and their application in Aplysina marine sponge studies

Dai, Y.; Pita, L.; Eustaquio, A. S.

10.1101/2024.08.01.606211 — genetics — Posted on 2024-08-06

4380 Conservation of animal genome structure is the exception not the rule

Lewin, T. D.; Liao, I. J.-Y.; Luo, Y.-J.

10.1101/2024.08.02.606322 — evolutionary biology — Posted on 2024-08-06

4381 Cycle-frequency content EEG analysis improves the assessment of respiratory-related cortical activity

Navarro-Sune, X.; Raux, M.; Hudson, A. L.; Similowski, T.; Chavez, M.

10.1101/2024.03.15.585182 — neuroscience — Posted on 2024-08-06

4382 Aversion-induced drug taking and escape behavior involve similar nucleus accumbens core dopamine signaling signatures

Grafelman, E. M.; Cote, B. E.; Vlach, L.; Geise, E.; Padula, G. N.; Wheeler, D. S.; Hearing, M. C.; Mantsch, J. R.; Wheeler, R. A.

10.1101/2024.08.05.606651 — neuroscience — Posted on 2024-08-05

4383 Amyloid, Tau, and APOE in Alzheimer's Disease: Impact on White Matter Tracts

Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.

10.1101/2024.08.05.606560 — neuroscience — Posted on 2024-08-05

4384 The molecular diversity of hippocampal regions and strata at synaptic resolution revealed by integrated transcriptomic and proteomic profiling

Kaulich, E.; Waselenchuk, Q.; Fuerst, N.; Desch, K.; Mosbacher, J.; Ciirdaeva, E.; Juengling, M.; Tushev, G.; Langer, J.; Schuman, E. M.

10.1101/2024.08.05.606570 — neuroscience — Posted on 2024-08-05

4385 Investigating cocaine- and abstinence-induced effects on astrocyte gene expression in the nucleus accumbens

Franklin, J. P.; Testen, A.; Mieczkowski, P. A.; Hepperla, A.; Crynen, G.; Simon, J. M.; Wood, J. D.; Harder, E. V.; Bellinger, T. J.; Witt, E. A.; Powell, N. L.; Reissner, K. J.

10.1101/2024.08.05.606656 — neuroscience — Posted on 2024-08-05

4386 A familial, telomere-to-telomere reference for human de novo mutation and recombination from a four-generation pedigree

Porubsky, D.; Dashnow, H.; Sasani, T. A.; Logsdon, G. A.; Hallast, P.; Noyes, M. D.; Kronenberg, Z. N.; Mokveld, T.; Koundinya, N.; Nolan, C.; Steely, C. J.; Guarracino, A.; Dolzhenko, E.; Harvey, W. T.; Rowell, W. J.; Grigorev, K.; Nicholas, T. J.; Oshima, K. K.; Lin, J.; Ebert, P.; Watkins, W. S.; Leung, T. Y.; Hanlon, V. C. T.; McGee, S.; Pedersen, B. S.; Goldberg, M. E.; Happ, H. C.; Jeong, H.; Munson, K. M.; Hoekzema, K.; Chan, D. D.; Wang, Y.; Knuth, J.; Garcia, G. H.; Fanslow, C.; Lambert, C.; Lee, C.; Smith, J. D.; Levy, S. E.; Mason, C. E.; Garrison, E.; Lansdorp, P. M.; Neklason, D.

10.1101/2024.08.05.606142 — genomics — Posted on 2024-08-05

4387 Sex-specific effects of early-life adversity on adult fitness in a wild mammal

Drake, E. D.; Ravindran, S.; Bal, X.; Pilkington, J. G.; Pemberton, J. M.; Nussey, D. H.; Froy, H.

10.1101/2024.08.05.606598 — evolutionary biology — Posted on 2024-08-05

4388 Increased vowel contrast and intelligibility in connected speech induced by sensorimotor adaptation

Beach, S. D.; Johnson, S. A.; Parrell, B.; Niziolek, C. A.

10.1101/2024.08.04.606537 — neuroscience — Posted on 2024-08-05

4389 Random Sanitization in DNA information storage using CRISPR-Cas12a

Shen, H.; Weng, Z.; Zhao, H.; Song, H.; Wang, F.; Fan, C.; Song, P.

10.1101/2024.08.04.606549 — synthetic biology — Posted on 2024-08-05

4390 A biodegradable and restorative peripheral neural interface for the interrogation of neuropathic injuries

Wang, L.; Zhang, T.; Lei, J.; Wang, S.; Guan, Y.; Chen, K.; Li, C.; Song, Y.; Li, W.; Wang, S.; Jia, Z.; Chen, S.; Bai, J.; Yu, B.; Yang, C.; Sun, P.; Wang, Q.; Sheng, X.; Peng, J.; Fan, Y.; Wang, L.; Zhang, M.; Wang, Y.; Yin, L.

10.1101/2024.08.05.606715 — bioengineering — Posted on 2024-08-05

4391 Rational design paving the way for improving glucose tolerance and catalytic properties of a β-glucosidase from Acetivibrio thermocellus

Kamale, C.; Rauniyar, A.; Bhaumik, P.

10.1101/2024.08.05.606605 — biochemistry — Posted on 2024-08-05

4392 ECT2 peptide sequences outside the YTH domain regulate its m6A-RNA binding

Seigneurin-Berny, D.; Karczewski, C.; Delaforge, E.; Yaacoub, K.; Gaspar Litholdo, C.; Favory, J.-J.; Ringkjobing Jensen, M.; Bousquet-Antonelli, C.; Verdel, A.

10.1101/2024.08.05.606563 — biochemistry — Posted on 2024-08-05

4393 U-rich elements drive pervasive cryptic splicing in 3' UTR massively parallel reporter assays

Dao, K.; Jungers, C.; Djuranovic, S.; Mustoe, A.

10.1101/2024.08.05.606557 — biochemistry — Posted on 2024-08-05

4394 Multi-species cryoEM calibration and workflow verification standard

Bobe, D.; Kopylov, M.; Miller, J.; Owji, A. P.; Eng, E. T.

10.1101/2024.08.05.606612 — biochemistry — Posted on 2024-08-05

4395 The molecular basis of Human FN3K mediated phosphorylation of glycated substrate

Garg, A.; On, K. F.; Xiao, Y.; Elkayam, E.; Cifani, P.; David, Y.; Joshua-Tor, L.

10.1101/2024.08.05.606604 — biochemistry — Posted on 2024-08-05

4396 EXOSC4 is recruited by histone H3 co-modified with K9me3 and acetylations to surveil non-coding transcription

Stransky, S.; Cutler, R.; Aguilan, J.; DeAngelo, J. D.; Shechter, D.; Sidoli, S.

10.1101/2024.08.05.606680 — biochemistry — Posted on 2024-08-05

4397 Chromatin-dependent motif syntax defines differentiation trajectories

Durdu, S.; Iskar, M.; Isbel, L.; Hoerner, L.; Wirbelauer, C.; Burger, L.; Hess, D.; Iesmantavicius, V.; Schubeler, D.

10.1101/2024.08.05.606702 — genomics — Posted on 2024-08-05

4398 Variant-to-function dissection of rare non-coding GWAS loci with high impact on blood traits

Tardaguila, M.; Soranzo, N.; Von Schiller, D.; Colombo, M.; Gori, I.; Coomber, E. L.; Vanderstichele, T.; Benaglio, P.; Chiereghin, C.; Gerety, S. S.; Vuckovic, D.; Landini, A.; Clerici, G.; Albers, P. K.; Walter, K.; Kundu, K.; Pirastu, N.; Ray-Jones, H.; Burnham, K. L.; Tokolyi, A.; Persyn, E.; Spivakov, M.; Watt, S.; Inouye, M.; Paul, D. S.; Davenport, E.; Sahlen, P.; Sankaran, V. G.

10.1101/2024.08.05.606572 — genetics — Posted on 2024-08-05

4399 Sequences within and upstream of the mouse Ets1 gene drive high level expression in B cells, but are not sufficient for consistent expression in T cells

Kearly, A.; Saelee, P.; Bard, J.; Sinha, S.; Satterthwaite, A.; Garrett-Sinha, L. A.

10.1101/2024.08.02.606433 — genetics — Posted on 2024-08-05

4400 Inferring the composition of a mixed culture of natural microbial isolates by deep sequencing

Voorhies, M. S.; Joehnk, B.; Uehling, J.; Walcott, K.; Dubin, C.; Mead, H.; Homer, C.; Galgiani, J.; Barker, B.; Brem, R.; Sil, A.

10.1101/2024.08.05.606565 — genetics — Posted on 2024-08-05

4401 Context effects on repair of 5'-overhang DSB induced by Cas12a in Arabidopsis.

Lageix, S.; Hernandez Sanchez-Rebato, M.; Gallego, M. E.; Verbeke, J.; Bidet, Y.; Viala, S.; White, C. I.

10.1101/2024.08.05.606594 — genetics — Posted on 2024-08-05

4402 Phylogenomics resolve the systematics and biogeography of the ant tribe Myrmicini and tribal relationships within the hyperdiverse ant subfamily Myrmicinae

Prebus, M. M.; Rabeling, C.

10.1101/2024.08.01.606207 — evolutionary biology — Posted on 2024-08-05

4403 Uncoupling the functional roles of Coronavirus Nsp1

Baeumlin, E.; Andenmatten, D.; Luginbuehl, J.; Lalou, A.; Schwaller, N.; Karousis, E. D.

10.1101/2024.08.05.606569 — molecular biology — Posted on 2024-08-05

4404 An enhanced Eco1 retron editor enables precision genome engineering in human cells from a single-copy integrated lentivirus

Cattle, M. A.; Aguado, L. C.; Sze, S.; Wang, D. Y.; Papagiannakopoulos, T.; Smith, S.; Rice, C. M.; Schneider, W. M.; Poirier, J. T.

10.1101/2024.08.05.606586 — molecular biology — Posted on 2024-08-05

4405 HIF1α controls steroidogenesis under acute hypoxic stress

Ariyeloye, S.; Watts, D.; Jaykar, M.; Ermis, C.; Krueger, A.; Kaden, D.; Stepien, B. K.; Alexaki, V. I.; Peitzsch, M.; Bechmann, N.; El-Armouche, A.; Wielockx, B.

10.1101/2024.08.05.606625 — molecular biology — Posted on 2024-08-05

4406 Circadian clock disruption and growth of kidney cysts in autosomal dominant polycystic kidney disease

Jamadar, A.; Ward, C. J.; Remadevi, V.; Varghese, M. M.; Pabla, N. S.; Gumz, M. L.; Rao, R.

10.1101/2024.08.05.606676 — molecular biology — Posted on 2024-08-05

4407 A modular self-assembling and self-adjuvanting multiepitope peptide nanoparticle vaccine platform to improve the efficacy and immunogenicity of BCG

Zhao, G.; Sathkumara, H.; Miranda-Hernandez, S.; Seifert, J.; Valencia Hernandez, A. M.; Puri, M.; Huang, W.; Toth, I.; Daly, N.; Skwarczynski, M.; Kupz, A.

10.1101/2024.08.04.606253 — microbiology — Posted on 2024-08-05

4408 Increased Nutrient Levels Enhance the Bacterial Contribution to an Algal-Bacterial Extracellular Matrix

Lipsman, V.; Segev, E.

10.1101/2024.08.05.606509 — microbiology — Posted on 2024-08-05

4409 Molecular Tracking and Cultivation Reveal Ammonia Oxidizing Archaea as Integral Members of the Human Skin Microbiome

Mahnert, A.; Dreer, M.; Perier, U.; Melcher, M.; Duller, S.; Lehnen, A.; Goessler, T.; Brunner, D.; Graier, T.; Wolf, P.; Ponce-Toledo, R. I.; Hodgskiss, L.; Kerou, M.; Moissl-Eichinger, C.; Schleper, C.

10.1101/2024.08.05.606590 — microbiology — Posted on 2024-08-05

4410 Metagenome-based diversity and functional analysis of culturable microbes in sugarcane

Lin, H.; Wu, L.; Zhang, L.; Ta, Q. K.; Liu, P.; Song, J.; Yang, X.

10.1101/2024.08.05.606635 — microbiology — Posted on 2024-08-05

4411 Drug-induced differential culturability in diverse strains of Mycobacterium tuberculosis.

March, V. F. A.; Maghradze, N.; Mchedlishvili, K.; Avaliani, T.; Aspindzelashvili, R.; Avaliani, Z.; Kipiani, M.; Tukvadze, N.; Jugheli, L.; Bouaouina, S.; Doetsch, A.; Goig, G. A.; Gagneux, S.; Borrell Farnov, S.

10.1101/2024.08.05.606579 — microbiology — Posted on 2024-08-05

4412 Scarless circular mRNA-based CAR-T cell therapy elicits superior anti-tumor efficacy

Hu, Q.; Zhao, H.; Zhou, K.; Hua, X.; Zhang, X.

10.1101/2024.08.05.606578 — immunology — Posted on 2024-08-05

4413 A mRNA Vaccine Encoding for a 60-mer G Glycoprotein Nanoparticle Elicits a Robust Neutralizing Antibodies Response Against the Nipah Virus

Brandys, P.; Albarino, C. G.; Jain, S.; Merenkova, I.; Schork, N. J.; Deng, A.; Valiere, M.; Herold, J.

10.1101/2024.08.05.606671 — immunology — Posted on 2024-08-05

4414 Mapping Kappa Opioid Receptor Binding in Titi Monkeys with 11C-GR103545 PET

Almeida, A. J. D.; Hobson, B. A.; Savidge, L. E.; Manca, C.; Paulus, J. P.; Bales, K. L.; Chaudhari, A. J.

10.1101/2024.08.01.606042 — neuroscience — Posted on 2024-08-05

4415 Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data

Wei, L.; Mast, F. D.; Aitchison, J. D.; Kaushansky, A.

10.1101/2024.08.01.606198 — systems biology — Posted on 2024-08-05

4416 Colorimetric CRISPR Biosensor: A Case Study with Salmonella Typhi

Pascual-Garrigos, A.; Lozano-Torres, B.; Das, A.; Molloy, J. C.

10.1101/2024.08.05.606709 — synthetic biology — Posted on 2024-08-05

4417 Transcriptional and Metabolic Mechanism of Carbon Dots Enhancing Rice Growth and Resistance by Promoting Root

Li, Y.; Xu, R.; Qi, J.; Lei, S.; Han, Q.; Ma, C.; Ru, Y.; Wang, H.

10.1101/2024.08.01.606230 — physiology — Posted on 2024-08-05

4418 Rapamycin increases murine lifespan but does not reduce mineral volume in the Matrix GLA Protein (MGP) knockout mouse model of medial arterial calcification.

Behzadi, P.; Cuevas, R. A.; Crane, A.; Wendling, A. A.; Chu, C. C.; Moorhead, W. J.; Wong, R.; Brown, M.; Tamakloe, J.; Suresh, S.; Saleh, P.; Jaffe, I. A.; Kuipers, A. L.; Lukashova, L.; Verdelis, K.; St. Hilaire, C.

10.1101/2024.08.01.606196 — physiology — Posted on 2024-08-05

4419 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles

Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Roest, F. F.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.

10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-08-05

4420 Elucidating ATP's Role as Solubilizer of Biomolecular Aggregate

Sarkar, S.; Gupta, S.; Mahato, C.; Das, D.; Mondal, J.

10.1101/2024.01.15.575740 — biochemistry — Posted on 2024-08-05

4421 Ubiquitin-specific protease 8 controls B-cell proteostasis and survival representing a target in multiple myeloma

Dufner, A.; Thery, F.; Monaco, G.; Lazarevic, J. L.; Gorka, O.; Chevalier, N.; Frosch, M.; van der Heden van Noort, G. J.; Prinz, M.; Gross, O.; Geurink, P. P.; Schamel, W. W.; Heissmeyer, V.; Denzel, M. S.; Bruns, H.; Schemionek, M.; Impens, F.; Knobeloch, K.-P.

10.1101/2024.04.26.591134 — molecular biology — Posted on 2024-08-05

4422 IPMK Deficiency Reduces Skeletal Muscle Oxidative Metabolism and Exercise Capacity

Lee, J.-H.; Jung, I.-R.; Tu-Sekine, B.; Jin, S.; Anokye-Danso, F.; Ahima, R. S.; Kim, S. F.

10.1101/2024.07.28.605526 — molecular biology — Posted on 2024-08-05

4423 Disentangling the mutational effects on protein stability and interaction of human MLH1

Larsen-Ledet, S.; Stein, A.

10.1101/2024.07.28.605491 — molecular biology — Posted on 2024-08-05

4424 Design, optimization, and inference of biphasic decay of infectious virus particles

Seurat, J.; Gerbino, K. R.; Meyer, J. R.; Borin, J. M.; Weitz, J. S.

10.1101/2024.02.23.581735 — microbiology — Posted on 2024-08-05

4425 Eyes robustly blink to musical beats like tapping

Wu, Y.; Teng, X.; Du, Y.

10.1101/2024.07.04.602077 — neuroscience — Posted on 2024-08-05

4426 Striatal cholinergic interneuron pause response requires Kv1 channels, is absent in dyskinetic mice, and is restored by dopamine D5 receptor inverse agonism

Tubert, C.; Paz, R. M.; Stahl, A. M.; Rela, L.; Murer, M. G.

10.1101/2024.05.31.596877 — neuroscience — Posted on 2024-08-05

4427 The interferon/STAT1 signaling axis is a common feature of tumor-initiating cells in breast cancer

Souto, E. P.; Gong, P.; Landua, J. D.; Srinivasan, R. R.; Ganesan, A.; Dobrolecki, L. E.; Purdy, S. C.; Pan, X.; Zeosky, M.; Chung, A.; Yi, S. S.; Ford, H. L.; Lewis, M. T.

10.1101/2023.09.15.557958 — cancer biology — Posted on 2024-08-05

4428 A modified dual preparatory method for improved isolation of nucleic acids from laser microdissected fresh-frozen human cancer tissue specimens

Kimble, D. C.; Litzi, T. J.; Snyder, G.; Olowu, V.; TaQee, S.; Conrads, K. A.; Loffredo, J.; Bateman, N. W.; Alba, C.; Rice, E.; Shriver, C. D.; Maxwell, G. L.; Dalgard, C.; Conrads, T. P.

10.1101/2024.08.02.606193 — biochemistry — Posted on 2024-08-05

4429 Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen.

Sharninghausen, R.; Hwang, J.; Dennison, D.; Baldridge, R.

10.1101/2023.06.21.546000 — cell biology — Posted on 2024-08-05

4430 WITHDRAWN: Experimental verification on "Telomere DNA and ribosomal DNA co-regulation model for cell senescence"

Huang, B.; Wu, Z.

10.1101/2024.07.23.604700 — cell biology — Posted on 2024-08-05

4431 Involvement of OsS40-14 in ROS and plastid organization related regulatory networks of dark-induced senescence in rice

Habiba, H.; Fan, C.; Hong, W.; Shi, X.; Wang, X.; Wang, W.; Lin, W.; Li, Y.; Ain, N. u.; Miao, Y.; Zheng, X.

10.1101/2024.08.01.606232 — plant biology — Posted on 2024-08-05

4432 Light quality affects chlorophyll biosynthesis and photosynthetic performance in Antarctic Chlamydomonas

Cvetkovska, M.; Poirier, M.; Fugard, K.

10.1101/2024.08.01.606229 — plant biology — Posted on 2024-08-05

4433 Enhanced pollen tube performance at high temperature contributes to thermotolerant fruit production in tomato.

Yimga, S. V. O.; Palaniappan, M.; Pryze, K.; Jong, E.; Ali, M. F.; Styler, B.; Almasaud, R. A.; Harkey, A. F.; Reid, R. W.; Loraine, A. E.; Smith, S. E.; Muday, G. K.; Pease, J. B.; Palanivelu, R.; Johnson, M. A.

10.1101/2024.08.01.606234 — plant biology — Posted on 2024-08-05

4434 Low-ABC: a robust demographic Inference from low-coverage whole-genome data through ABC

Vizzari, M. T.; Ghirotto, S.; Agostini, R. B.; Delser, P. M.; Cassidy, L.; Manica, A.; Benazzo, A.

10.1101/2024.08.01.606209 — genomics — Posted on 2024-08-05

4435 Genomic prediction of cereal crop architecture traits using models informed by gene regulatory circuitries from maize

Bertolini, E.; Manjunath, M.; Ge, W.; Murphy, M. D.; Inaoka, M.; Fliege, C.; Eveland, A. L.; Lipka, A. E.

10.1101/2024.08.01.606170 — genetics — Posted on 2024-08-05

4436 Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models

Lim, J. L.; Jensen, S. M.; Plomp, J. J.; Vankerckhoven, B.; Kneip, C.; Coppejans, R.; Steyaert, C.; Moens, K.; De Clercq, L.; Tannemaat, M. R.; Ulrichts, P.; Silence, K.; van der Maarel, S. M.; Vergoossen, D. L. E.; Vanhauwaert, R.; Verschuuren, J. J.; Huijbers, M. G.

10.1101/2024.08.01.606156 — neuroscience — Posted on 2024-08-05

4437 Synapse weakening-induced caspase-3 activity confers specificity to microglia-mediated synapse elimination

Yu, Z.; Gutu, A.; Kim, N.; O'Shea, E. K.

10.1101/2024.08.02.606316 — neuroscience — Posted on 2024-08-05

4438 Site-resolved energetic information from HX/MS experiments

Lu, C.; Wells, M. L.; Reckers, A.; Glasgow, A.

10.1101/2024.08.04.606547 — biophysics — Posted on 2024-08-05

4439 The Origins of Arginine "Magic": Guanidinium Like-Charge Ion Pairing and Oligoarginine Aggregation in Water by NMR, Cryoelectron Microscopy, and Molecular Dynamics Simulations

Biriukov, D.; Osifova, Z.; Hong, M. N. T.; Mason, P. E.; Dracinsky, M.; Jungwirth, P.; Heyda, J.; Morandi, M. I.; Vazdar, M.

10.1101/2024.08.04.606526 — biophysics — Posted on 2024-08-05

4440 Mechanical Implications of Cellular Viscoelasticity, Cortex Polarity, Superelasticity, and Cell-Cell Junctions in Curved Tissues

Perez-Tirado, A.; Unkelbach, U.; Oswald, T. A.; Rheinlaender, J.; Schaeffer, T. E.; Mukenhirn, M.; Honigmann, A.; Janshoff, A.

10.1101/2024.08.01.606202 — biophysics — Posted on 2024-08-05

4441 Resources modulate developmental shifts but not infection tolerance upon coinfection in an insect system

Schulz, N. K. E.; Asgari, D.; Liu, S.; Birnbaum, S. S. L.; Williams, A. M.; Prakash, A.; Tate, A. T.

10.1101/2024.08.01.606236 — ecology — Posted on 2024-08-05

4442 Buzz Pollination: Investigations of Pollen Expulsion using the Discrete Element Method

Boucher-Bergstedt, C. G.; Jankauski, M. G.; Johnson, E.

10.1101/2024.08.01.606085 — biophysics — Posted on 2024-08-05

4443 The actin cortex acts as a mechanical memory of morphology in confined migrating cells

Kalukula, Y.; Luciano, M.; Charras, G.; Brueckner, D.; Gabriele, S.

10.1101/2024.08.05.606589 — biophysics — Posted on 2024-08-05

4444 Integrity and miss grouping as support for clusters in agglomerative hierarchical methods: the R-package octopucs

MacGregor-Fors, I.; Guevara, R.

10.1101/2024.08.01.606070 — bioinformatics — Posted on 2024-08-05

4445 Sainsc: a computational tool for segmentation-free analysis of in-situ capture

Müller-Bötticher, N.; Tiesmeyer, S.; Eils, R.; Ishaque, N.

10.1101/2024.08.02.603879 — bioinformatics — Posted on 2024-08-05

4446 Screening great ape museum specimens for DNA viruses

Haemmerle, M.; Guellil, M.; Cheronet, O.; Sawyer, S.; Ruiz-Gartzia, I.; Lizano, E.; Rymbekova, A.; Gelabert, P.; Bernardi, P.; Han, S.; Trgovec-Greif, L.; Rattei, T.; Schuenemann, V. J.; Marques-Bonet, T.; Guschanski, K.; Calvignac-Spencer, S.; Pinhasi, R.; Kuhlwilm, M.

10.1101/2024.04.25.591107 — genomics — Posted on 2024-08-05

4447 Nanoscale volumetric fluorescence imaging via photochemical sectioning

Wang, W.; Ruan, X.; Liu, G.; Milkie, D. E.; Li, W.; Betzig, E.; Upadhyayula, S.; Gao, R.

10.1101/2024.08.01.605857 — neuroscience — Posted on 2024-08-05

4448 Experience-dependent modulation of collective behavior in larval zebrafish

Harpaz, R.; Phillips, M.; Goel, R.; Engert, F.; Fishman, M. C.

10.1101/2024.08.02.606403 — animal behavior and cognition — Posted on 2024-08-05

4449 Instantaneous Flow Analysis of Contractile Cytoskeletal Structures Affected by the Dysregulation of Kinesin and Tropomyosin Motors

Matov, A.

10.1101/2024.06.28.601275 — cell biology — Posted on 2024-08-05

4450 Increased listening effort and cochlear neural degeneration underlie behavioral deficits in speech perception in noise in normal hearing middle-aged adults.

Zink, M. E.; Zhen, L.; McHaney, J. R.; Klara, J.; Yurasits, K.; Cancel, V.; Flemm, O.; Mitchell, C.; Datta, J.; Chandrasekaran, B.; Parthasarathy, A.

10.1101/2024.08.01.606213 — neuroscience — Posted on 2024-08-05

4451 Machine learning enables high-throughput, low-replicate screening for novel anti-seizure targets and compounds using combined movement and calcium fluorescence in larval zebrafish

McGraw, C. M.; Poduri, A.

10.1101/2024.08.01.606228 — pharmacology and toxicology — Posted on 2024-08-05

4452 BRACE: A novel Bayesian-based imputation approach for dimension reduction analysis of alternative splicing at single-cell resolution

Wen, S.

10.1101/2024.08.01.606201 — bioinformatics — Posted on 2024-08-05

4453 GW: ultra-fast chromosome-scale visualisation of genomics data

Cleal, K.; Kearsey, A.; Baird, D. M.

10.1101/2024.07.26.605272 — bioinformatics — Posted on 2024-08-05

4454 Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics

Lewis-Healey, E.; Tagliazucchi, E.; Canales-Johnson, A.; Bekinschtein, T.

10.1101/2024.02.19.580985 — neuroscience — Posted on 2024-08-05

4455 Elraglusib induces cytotoxicity via direct microtubule destabilisation independently of GSK3 inhibition

Coats, J. T.; Li, S.; Tanaka, T. U.; Tauro, S.; Sutherland, C.; Saurin, A. T.

10.1101/2024.07.06.602326 — cancer biology — Posted on 2024-08-05

4456 Adhesion-driven vesicle translocation through membrane-covered pores

Baruah, N.; Midya, J.; Gompper, G.; Dasanna, A. K.; Auth, T.

10.1101/2024.05.20.594296 — biophysics — Posted on 2024-08-05

4457 Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding

Knejski, P. P.; Erramilli, S. K.; Kossiakoff, A. A.

10.1101/2023.08.01.551527 — biochemistry — Posted on 2024-08-05

4458 Modeling impairment of ionic regulation with extended Adaptive Exponential integrate-and-fire models

Depannemaecker, D.; Tesler, F.; Desroches, M.; Jirsa, V.; Destexhe, A.

10.1101/2024.08.01.606188 — neuroscience — Posted on 2024-08-05

4459 Drug Metabolism and Transport Capacity of Endothelial Cells, Pericytes, and Astrocytes: Implications for CNS Drug Disposition

Wilkins, H. N.; Knerler, S. A.; Warshanna, A.; Ortiz, R. C.; Haas, K.; Orsburn, B. C.; Williams, D. W.

10.1101/2024.08.01.606165 — pharmacology and toxicology — Posted on 2024-08-05

4460 Integrating Secondary Structure Information Enhances Phylogenetic Signal in Mitochondrial Protein Coding Genes

Cucini, C.; Nardi, F.; Pons, J.

10.1101/2024.08.01.606191 — evolutionary biology — Posted on 2024-08-05

4461 Modelling post-disturbance empirical patterns in a forest ecosystem

Zanchetta, D.; Maritan, A.; Azaele, S.

10.1101/2024.08.01.606184 — ecology — Posted on 2024-08-05

4462 Rapid reprogramming and stabilisation of homoeolog expression bias in hexaploid wheat biparental populations

Glombik, M.; Arunkumar, R.; Burrows, S.; Mogg, S. L.; Wang, X.; Borrill, P.

10.1101/2024.08.01.606180 — plant biology — Posted on 2024-08-05

4463 Socially driven negative feedback regulates activity and energy use in ant colonies

Porfiri, M.; Abaid, N.; Garnier, S.

10.1101/2024.08.01.606164 — biophysics — Posted on 2024-08-05

4464 Simultaneous silencing of gut nucleases and a vital target gene by adult dsRNA feeding enhances RNAi efficiency and mortality in Ceratitis capitata adults.

Saccone, G.; Aceto, S.; Salvemini, M.; Volpe, G.; Pennacchio, F.; Mazzucchiello, S. M.; Lucibelli, F.; Varone, M.; Baccaro, D.; Mattei, I.; Giordano, E.; Di Lelio, I.; Becchimanzi, A.; Rosati, N.

10.1101/2024.08.01.605863 — genetics — Posted on 2024-08-05

4465 The Paleozoic assembly of the holocephalian body plan far preceded post-Cretaceous radiations into the ocean depths

Brownstein, C. D.; Near, T. J.; Dearden, R. P.

10.1101/2024.08.01.606185 — evolutionary biology — Posted on 2024-08-05

4466 Mass Spectrometry Imaging of the Subchondral Bone in Osteoarthritis Reveals Tissue Remodeling of Extracellular Matrix Proteins that Precede Cartilage Loss

Schurman, C. A.; Bons, J.; Woo, J. J.; Yee, C.; Tao, N.; Alliston, T.; Angel, P.; Schilling, B.

10.1101/2024.08.03.606482 — cell biology — Posted on 2024-08-05

4467 Differential regulation of BAX and BAK apoptotic activity revealed by a novel small molecule

Li, K.; Yap, Y. Q.; Moujalled, D.; Sumardy, F.; Khakham, Y.; Giorgiou, A.; Jahja, M.; Lew, T.; DeSilva, M.; Luo, M.; Gong, J.; Roberts, A.; Yuan, Z.; Birkinshaw, R.; Czabotar, P. E.; Lowes, K.; Huang, D.; Kile, B.; Wei, A.; Dewson, G.; van Delft, M. F.; Lessene, G.

10.1101/2024.08.04.605933 — cell biology — Posted on 2024-08-05

4468 FoldToken4: Consistent & Hierarchical Fold Language

Gao, Z.; Tan, C.; Li, S. Z.

10.1101/2024.08.04.606514 — molecular biology — Posted on 2024-08-04

4469 Weight loss-induced adipose macrophage memory improves local Staphylococcus aureus clearance in male mice

Bolden, M.; Davis, X. D.; Sherwood, E. R.; Bohannon, J. K.; Caslin, H. L.

10.1101/2024.08.03.606494 — immunology — Posted on 2024-08-04

4470 Neural representational precision of distance predicts arithmetic performance

Zhao, H.; Qi, W.; Yao, Y.; Lv, J.; Qin, S.

10.1101/2024.08.01.605970 — neuroscience — Posted on 2024-08-04

4471 Topological embedding and directional feature importance in ensemble classifiers for multi-class classification

Rocha Liedl, E.; Yassin, S. M.; Kasapi, M.; Posma, J. M.

10.1101/2024.08.01.605982 — bioinformatics — Posted on 2024-08-04

4472 Structural and functional characterization of SidF, a possible dual substrate Aspergillus fumigatus N5-acetyl-N5-hydroxy-L-ornithine transacetylase

Poonsiri, T.; Demitri, N.; Stransky, J.; Haas, H.; CIANCI, M.; Benini, S.

10.1101/2024.08.03.606473 — biochemistry — Posted on 2024-08-04

4473 Chromosome structural rearrangements in invasive haplodiploid ambrosia beetles revealed by the genomes of Euwallacea fornicatus and Euwallacea similis (Coleoptera, Curculionidae, Scolytinae)

Bickerstaff, J. R.; Walsh, T.; Court, L.; Pandey, G.; Ireland, K.; Cousins, D.; Caron, V.; Wallenius, T.; Slipinski, A.; Rane, R.; Escalona, H.

10.1101/2024.06.25.600716 — genomics — Posted on 2024-08-04

4474 Social and environmental predictors of gut microbiome age in wild baboons

Dasari, M. R.; Roche, K. E.; Jansen, D.; Anderson, J.; Alberts, S. C.; Tung, J.; Gilbert, J. A.; Blekhman, R.; Mukherjee, S.; Archie, E.

10.1101/2024.08.02.605707 — evolutionary biology — Posted on 2024-08-04

4475 The effect of parental conflict in imprinting genes in A. lyrata.

Le veve, A.; Iltas, O.; Dutheil, J.; Lafon Placette, C.

10.1101/2024.08.01.606153 — evolutionary biology — Posted on 2024-08-04

4476 Substantial hierarchical reductions of genetic and morphological traits in the evolution of rotiferan parasites

Herlyn, H.; Hembrom, A. A.; Tosar, J. P.; Mauer, K. M.; Schmidt, H.; Dezfuli, B. S.; Bachmann, L.; Sarkies, P.; Peterson, K. J.; Fromm, B.

10.1101/2024.08.01.605096 — evolutionary biology — Posted on 2024-08-04

4477 Flower size evolution in the Southwest Pacific

Ciarle, R.; Burns, K. C.; Mologni, F.

10.1101/2023.12.12.571326 — evolutionary biology — Posted on 2024-08-04

4478 Nematodes Vector Bacteriophages in Compost and Soil

van Sluijs, L.; Dietz, C.; Van Noort, F.; Helder, J.; Zwart, M. W.; Mason-Jones, K.

10.1101/2024.08.02.605737 — ecology — Posted on 2024-08-04

4479 Factors affecting the individual probability of infection with a prevalent pathogen (Mycoplasma) and the effect on Griffon vultures' movement behavior

Anglister, N.; Crafton, M.; Avraham Saada, O.; Acacio, M.; Vaadia, G.; Hatzofe, O.; Miller, Y.; Mikula, I.; Pinter-Wollman, N.; Lysynyansky, I.; Spiegel, O.

10.1101/2024.08.01.606137 — ecology — Posted on 2024-08-04

4480 FoldToken4: Consistent & Hierarchical Fold Language

Gao, Z.; Tan, C.; Li, S. Z.

10.1101/2024.08.04.606514 — molecular biology — Posted on 2024-08-04

4481 CyNET- a network analysis framework for high dimensionality, system level analyses of the functional Immunome

Kumar, P.; Yeo, J. G.; Poh, S. L.; Nur Hazirah, S.; Sutamam, N. B.; ang, G. W.; Chellamuthu, V. R.; Wasser, M.; Yeo, K. T.; Leong, J. Y.; Ramakrishna, L.; Arkachaisri, T.; Albani, S.

10.1101/2024.07.15.603495 — immunology — Posted on 2024-08-04

4482 Dendritically localized RNAs are packaged as diversely composed Ribonucleoprotein particles with heterogeneous copy number states

Tarannum, R.; Mun, G.; Quddos, F.; Swanger, S. A.; Steward, O.; Farris, S.

10.1101/2024.07.13.603387 — neuroscience — Posted on 2024-08-04

4483 Proliferative arrest induces neuron differentiation and innate immune responses in control and Creutzfeldt-Jakob Disease agent infected rat septal neurons

pagano, n.; aguilar, g.; Garcia-Milian, R.; manuelidis, l.

10.1101/2024.07.26.605349 — neuroscience — Posted on 2024-08-04

4484 An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging neurons

Abdelmageed, M.; Palamisamy, P.; Vernail, V.; Silberman, Y.; Paul, S.; Paul, A.

10.1101/2023.09.27.559771 — neuroscience — Posted on 2024-08-04

4485 Ontology-based modeling, integration, and analysis of heterogeneous clinical, pathological, and molecular kidney data for precision medicine

He, Y.; Barisoni, L.; Rosenberg, A. Z.; Robinson, P. N.; Diehl, A. D.; Chen, Y.; Phuong, J. P.; Hansen, J.; Herr, B. W.; Borner, K.; Schaub, J.; Bonevich, N.; Arnous, G.; Boddapati, S.; Zheng, J.; Alakwaa, F.; Sarder, P.; Duncan, W. D.; Liang, C.; Valerius, M. T.; Jain, S.; Iyengar, R.; Himmelfarb, J.; Kretzler, M.; Kidney Precision Medicine Project,

10.1101/2024.04.01.587658 — bioinformatics — Posted on 2024-08-04

4486 Integrating long-read RNA sequencing improves locus-specific quantification of transposable element expression

Lee, S.; Barbour, J. A.; Tam, Y. M.; Yang, H.; Huang, Y.; Wong, J. W. H.

10.1101/2023.03.21.533716 — genomics — Posted on 2024-08-04

4487 Heterogeneity of the human immune response to malaria infection and vaccination driven by latent cytomegalovirus infection

Mukhiya, R.; Fleischmann, W. A.; Loughland, J. R.; Chan, J.-A.; de Labastida Rivera, F.; Andrew, D.; Beeson, J. G.; McCarthy, J. S.; Barber, B.; Lopez, J. A.; Engwerda, C.; Thomson-Luque, R.; Boyle, M. J.

10.1101/2024.04.28.591548 — immunology — Posted on 2024-08-04

4488 The multi-level effect of chlorpyrifos during clownfish metamorphosis

Reynaud, M.; Vianello, S.; Lee, S.-H.; Salis, P.; Dusseune, M.; Wu, K.; Frederich, B.; Lecchini, D.; Besseau, L.; Roux, N.; Laudet, V.

10.1101/2024.08.02.606305 — developmental biology — Posted on 2024-08-04

4489 Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1.1

Wolf van der Meer, J.; Larue, A.; van der Knaap, J.; Chalkley, G.; Sijm, A.; Beikmohammadi, L.; Kozhevnikova, E. N.; van der Vaart, A.; Tilly, B.; Bezstarosti, K.; Dekkers, D. H. W.; Doff, W. A. S.; van de Wetering-Tieleman, J.; Lanko, K.; Barakat, T. S.; Allertz, T.; van Haren, J.; Demmers, J. A.; Atlasi, Y.; Verrijzer, C. P.

10.1101/2024.08.04.606521 — molecular biology — Posted on 2024-08-04

4490 Microcystins are critical for the toxic Microcystis to survive long-term nitrogen starvation

Lian, X.-Y.; Qiu, G.-W.; Zheng, W.-C.; Shang, J.-L.; Xu, H.-F.; Dai, G.-Z.; Gan, N.-Q.; Zhang, Z.-C.; Qiu, B.-S.

10.1101/2024.08.03.606466 — microbiology — Posted on 2024-08-04

4491 Interferon-γ driven differentiation of monocytes into PD-L1+ and MHC II+ macrophages and the frequency of Tim-3+ tumor-reactive CD8+ T cells within the tumor microenvironment predict a positive response to anti-PD-1-based therapy in tumor-bearing mice

Gabrilo, J.; Vande Velde, S.; Henin, C.; Denanglaire, S.; Azouz, A.; Boon, L.; Van den Eynde, B. J.; Moser, M.; Goriely, S.; Leo, O.

10.1101/2024.08.01.606242 — immunology — Posted on 2024-08-04

4492 Both T and B cells contribute to dysregulated activation and differentiation of CD4+ T cells in Activated PI3K delta syndrome 1

Bier, J.; Lau, A.; Jackson, K. J.; Ruiz-Diaz, S.; Brink, R.; Tangye, S. G.; Deenick, E. K.

10.1101/2024.08.04.606503 — immunology — Posted on 2024-08-04

4493 Sensory population activity reveals confidence computations in the primate visual system

Boundy-Singer, Z. M.; Ziemba, C. M.; Goris, R. L. T.

10.1101/2024.08.01.606172 — neuroscience — Posted on 2024-08-04

4494 Primed responses to damage signals mediate mycorrhiza-induced resistance in tomato plants

Minchev, Z.; Garcia, J. M.; Pozo, E.; Pozo, M. J.; Gamir, J.

10.1101/2024.08.01.606158 — plant biology — Posted on 2024-08-04

4495 Transcriptomic Meta-analysis Identifies Long Non-Coding RNAs Mediating Zika's Oncolytic Impact in Glioblastoma Multiforme

Kousa, Y. A.; Singh, S.; Horvath, A.; Tomasso, F.; Nazarian, J.; Henderson, L.; Mansour, T. A.

10.1101/2024.08.04.605859 — cancer biology — Posted on 2024-08-04

4496 Insertion and Anchoring of HIV-1 Fusion Peptide into Complex Membrane Mimicking Human T-cell

Zhao, M.; Lopes, L. J. S.; Sahni, H.; Yadav, A.; Do, H. N.; Reddy, T.; Lopez, C. A.; Neale, C.; Gnanakaran, S.

10.1101/2024.08.02.606381 — biophysics — Posted on 2024-08-04

4497 SeuratExtend: Streamlining Single-Cell RNA-Seq Analysis Through an Integrated and Intuitive Framework

Hua, Y.; Weng, L.; Zhao, F.; Rambow, F.

10.1101/2024.08.01.606144 — bioinformatics — Posted on 2024-08-04

4498 An Evolutionary Statistics Toolkit for Simplified Sequence Analysis on Web with Client-Side Processing

Karagol, A.; Karagol, T.

10.1101/2024.08.01.606148 — bioinformatics — Posted on 2024-08-04

4499 Mechanochemical forces regulate the composition and function of CAT tails

Khan, D.; Vinayak, A. A.; Sitron, C. S.; Brandman, O.

10.1101/2024.08.02.606406 — biochemistry — Posted on 2024-08-04

4500 Intra-subgenome regulation induces unbalanced expression and function among bread wheat homoeologs

Wang, X.; Liu, Y.; Zhao, P.; Hou, W.; Cheng, M.; Shi, X.; Simmonds, J.; Borrill, P.; Ji, W.; Xu, S.

10.1101/2024.08.01.606124 — genomics — Posted on 2024-08-04

4501 Interpreting the CTCF-mediated sequence grammar of genome folding with AkitaV2

Smaruj, P. N.; Kamulegeya, F.; Kelley, D. R.; Fudenberg, G.

10.1101/2024.08.01.606065 — genomics — Posted on 2024-08-04

4502 A new clade of pararetroviruses distantly related to hepadnaviruses and nackednaviruses

Buigues, J.; Vinals, A.; Martinez-Recio, R.; Monros, J. S.; Cuevas, J. M.; Sanjuan, R.

10.1101/2024.08.02.606351 — evolutionary biology — Posted on 2024-08-04

4503 Root traits and tree functional groups determine variability in root exudation and N uptake rates in mature temperate trees

Oh, Y. E.; Midgley, M. G.; McCormack, M. L.; Beidler, K. V.; McCall, M.; Henderson, S.; Braghiere, R. K.; Phillips, R. P.

10.1101/2024.08.01.606171 — ecology — Posted on 2024-08-04

4504 Modeling the transmission dynamics of African swine fever virus within commercial swine barns: Quantifying the contribution of multiple transmission pathways

Deka, A.; Galvis, J. A.; Fleming, C.; Safari, M.; Yeh, C.-A.; Machado, G.

10.1101/2024.08.02.604486 — ecology — Posted on 2024-08-04

4505 3D Reconstruction of Neuronal Allometry and Neuromuscular Projections in Asexual Planarians Using Expansion Tiling Light Sheet Microscopy

Lu, J.; Xu, H.; Wang, D.; Chen, Y.; Inoue, T.; Gao, L.; Lei, K.

10.1101/2024.08.01.606161 — developmental biology — Posted on 2024-08-04

4506 Isolation and molecular characterization of an enteric isolate of the Genotype-I Bovine coronavirus with notable mutations in the receptor binding domain of the spike glycoprotein and deletion downstream the RNA binding domain of the nucleocapsid protein.

Shah, A. U.; Gauger, P. C.; Hemida, M. H.

10.1101/2024.08.03.606496 — microbiology — Posted on 2024-08-04

4507 Computation or Weight Adaptation? Rethinking the Role of Plasticity in Learning

Lior, G.; Shalev, Y.; Stanovsky, G.; Goldstein, A.

10.1101/2024.03.07.583890 — neuroscience — Posted on 2024-08-04

4508 Conservation of dichromatin organization along regional centromeres

Dubocanin, D.; Hartley, G. A.; Cortes, A. E. S.; Mao, Y.; Hedouin, S.; Ranchalis, J. E.; Agarwal, A.; Logsdon, G.; Munson, K. M.; Real, T. D.; Mallory, B. J.; Eichler, E. E.; Biggins, S.; O'Neill, R. J.; Stergachis, A. B.

10.1101/2023.04.20.537689 — genomics — Posted on 2024-08-04

4509 Asynchronous abundance fluctuations can drive giant genotype frequency fluctuations

Ascensao, J. A.; Lok, K.; Hallatschek, O.

10.1101/2024.02.23.581776 — evolutionary biology — Posted on 2024-08-04

4510 Proteogenomics guided identification of functional neoantigens in non-small cell lung cancer

Nicholas, B.; Bailey, A.; McCann, K. J.; Wood, O.; Currall, E.; Johnson, P.; Elliott, T.; Ottensmeier, C.; Skipp, P.

10.1101/2024.05.30.596609 — immunology — Posted on 2024-08-04

4511 Tyrosinase-induced neuromelanin accumulation triggers rapid dysregulation and degeneration of the mouse locus coeruleus

Iannitelli, A. F.; Hassanein, L.; Mulvey, B.; Blankenship, H.; Liles, L. C.; Sharpe, A. L.; Pare, J.-F.; Segal, A.; Sloan, S. A.; Martinowich, K.; McCann, K. E.; Dougherty, J. D.; Smith, Y.; Beckstead, M. J.; Weinshenker, D.

10.1101/2023.03.07.530845 — neuroscience — Posted on 2024-08-04

4512 Driving forces for condensation of synapsin are governed by sequence-encoded molecular grammars

Hoffmann, C.; Ruff, K. M.; Edu, I.; Kyung Shinn, M.; Tromm, J.; King, M.; Pant, A.; Ausserwoeger, H.; Morgan, J.; Knowles, T.; Pappu, R. V.; Milovanovic, D.

10.1101/2024.08.03.606464 — biochemistry — Posted on 2024-08-04

4513 CRISPR-Cas13d as a molecular tool to achieve targeted gene expression knockdown in chick embryos

Kim, M.; Hutchins, E. J.

10.1101/2024.08.03.606488 — developmental biology — Posted on 2024-08-04

4514 Endothelial Immunosuppression in Atherosclerosis : Translational Control by Elavl1/HuR

Nicholas, S.-A. E.; Helming, S. R.; Menoret, A.; Pathoulas, C.; Xu, M. M.; Hensel, J.; Kimble, A. L.; Heineman, B.; Jellison, E. R.; Reese, B.; Zhou, B.; Rodriguez-Oquendo, A.; Vella, A. T.; Murphy, P. A.

10.1101/2024.08.02.605922 — cell biology — Posted on 2024-08-04

4515 Phylogeny, morphology, and behavior of the new ciliate species Stentor stipatus

Rajan, D. H.; Lee, B.; Albright, A.; Tang, E. J.; Maravillas, A.; Vargas, C.; Marshall, W. F.; Cortes, D.

10.1101/2024.08.03.606273 — cell biology — Posted on 2024-08-04

4516 PNPLA3(148M) Promotes Hepatic Steatosis by Interfering with Triglyceride Hydrolysis Through a Gain-of-Function Mechanism

Wang, Y.; Hong, S.; Hudson, H.; Kory, N.; Kinch, L. N.; Kozlitina, J.; Cohen, J. C.; Hobbs, H. H.

10.1101/2024.08.02.606015 — cell biology — Posted on 2024-08-04

4517 CaMKII induces an autophagy-dependent anabolic response in Articular Chondrocytes

Day, N. J.; Dutta, A.; Heluany, C. S.; Asopa, V.; Sochart, D.; Fielding, B.; Nalesso, G.

10.1101/2024.08.04.606243 — cell biology — Posted on 2024-08-04

4518 Polo-like kinase 1 prevents excess microtubule polymerization in C. elegans oocytes to ensure faithful meiosis

Narula, J. G.; Wignall, S. M.

10.1101/2024.08.03.606476 — cell biology — Posted on 2024-08-04

4519 Nascent flagellar basal bodies are immobilized by rod assembly in Bacillus subtilis

Dunn, C. M.; Foust, D.; Gao, Y.; Biteen, J. S.; Shaw, S. L.; Kearns, D. B.

10.1101/2024.08.02.606393 — cell biology — Posted on 2024-08-04

4520 Distance between miRNA responsive elements selectively enhances target specificity with reduced cellular toxicity by miRNA-mediated synergism

Mazumder, S.; Banerjee, U.; Sinsinwar, S.; Mandal, S.; Prusty, D.; Babele, P.; Das, B.; Manna, S. K.; Ray, J. G.; Chatterjee, R.

10.1101/2024.08.01.606174 — cancer biology — Posted on 2024-08-04

4521 Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies

Martinelli, S.; Hafner, K.; Ködel, M.; Arloth, J.; Gassen, N. C.; Binder, E.

10.1101/2024.08.03.606475 — molecular biology — Posted on 2024-08-04

4522 Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus

Zeng, H.; Ai, M.; Zhou, X.; Carrer, M.; Jafar-nejad, P.; Li, Y.; Gades, N. M.; Alexander, M. P.; Bautista, M. A.; Duarte Garcia, A. A.

10.1101/2024.08.01.606069 — immunology — Posted on 2024-08-04

4523 Autosomal Dominant-Hyper-IgE Syndrome patients contain pre-Th17-cells that are activated by opportunistic pathogens to produce IL-10

Moschetti, G.; Vasco, C.; Clemente, F.; Larghi, P.; Maioli, S.; Scarpa, E.; Carelli, E.; Pulvirenti, N.; Sarnicola, M. L.; Crosti, M.; Bel Imam, M.; van de Veen, W.; Rizzello, L.; Abrignani, S.; Baselli, L. A.; Dellepiane, R. M.; Carrabba, M.; Fabio, G.; Geginat, J.

10.1101/2024.08.01.606136 — immunology — Posted on 2024-08-04

4524 Exploration of the Metabolomic Mechanisms of Postmenopausal Hypertension Induced by Low Estrogen State

Li, Y.; Xin, H.; Lian, Z.; Zhang, W.

10.1101/2024.08.01.606107 — systems biology — Posted on 2024-08-04

4525 Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

Wu, W.; Yu, M.; Li, Q.; Zhao, Y.; Zhang, L.; Sun, Y.; Wang, Z.; Gong, Y.; Wang, W.; Liu, C.; Zhang, J.; Tang, Y.; Xu, X.; Guo, X.; Zhan, J.; Zhang, H.

10.1101/2024.08.01.606147 — cancer biology — Posted on 2024-08-04

4526 The AP2/ERF transcription factor HcERF5 confers drought tolerance via ABA-mediated signaling in kenaf

Luo, D.; Mubeen, S.; Rehman, M.; Cao, S.; Wang, C.; Yue, J.; Pan, J.; Jin, G.; Li, R.; Chen, T.; Chen, P.

10.1101/2024.08.01.606231 — molecular biology — Posted on 2024-08-04

4527 DREAMER: Exploring Common Mechanisms of Adverse Drug Reactions and Disease Phenotypes through Network-Based Analysis

Firoozbakht, F.; Elkjaer, M. L.; Handy, D.; Wang, R.; Chervontseva, Z.; Rarey, M.; Loscalzo, J.; Baumbach, J.; Tsoy, O.

10.1101/2024.07.20.602911 — systems biology — Posted on 2024-08-04

4528 Direct imaging of neural activity reveals neural circuits via spatiotemporal activation mapping

Keum, J.-Y.; Toi, P. T.; Park, S.; Chun, H.; Park, J.-Y.

10.1101/2024.07.31.606112 — neuroscience — Posted on 2024-08-04

4529 Single-molecule tracking-based drug screening

Watanabe, D.; Hiroshima, M.; Yasui, M.; Ueda, M.

10.1101/2023.11.12.566743 — pharmacology and toxicology — Posted on 2024-08-04

4530 A 3D-printed multi-compartment organ-on-chip platform with a tubing-free pump models communication with the lymph node

Cook, S. R.; Ball, A. G.; Mohammad, A.; Pompano, R. R.

10.1101/2024.05.20.594865 — bioengineering — Posted on 2024-08-04

4531 Daptomycin forms a stable complex with phosphatidylglycerol for selective uptake to bacterial membrane

Machhua, P.; Unnithan, V. G.; Liu, Y.; Jiang, Y.; Zhang, L.; Guo, Z.

10.1101/2023.10.01.560395 — biochemistry — Posted on 2024-08-04

4532 Kinetic Diagram Analysis: A Python Library for Calculating Steady-State Observables of Biochemical Systems Analytically

Awtrey, N. C.; Beckstein, O.

10.1101/2024.05.27.596119 — biochemistry — Posted on 2024-08-04

4533 Towards Stewardship of Wild Species and Their Domesticated Counterparts: A Case Study in Northern Wild Rice (Zizania palustris L.)

McGilp, L.; Haas, M. W.; Shao, M.; Millas, R.; Castell-Miller, C.; Kern, A.; Shannon, L. M.; Kimball, J.

10.1101/2022.08.25.505308 — genetics — Posted on 2024-08-04

4534 Members of an array of zinc finger proteins specify distinct Hox chromatin boundaries

Ortabozkoyun, H.; Huang, P.-Y.; Gonzalez-Buendia, E.; Cho, H.; Kim, S. Y.; Tsirigos, A.; Mazzoni, E. O.; Reinberg, D.

10.1101/2023.04.25.538167 — genetics — Posted on 2024-08-04

4535 Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathway

Agarwal, P.; Ghosh, S. K.

10.1101/2024.07.26.605363 — cell biology — Posted on 2024-08-04

4536 Prevalence of errors in lab-made plasmids across the globe

Bai, X.; Hong, J. F.; Yu, S.; Hu, D. Y.; Chen, A. Y.; Rich, C. A.; Shi, S. J.; Xu, S. Y.; Croucher, D. M.; Mussar, K. J.; Meng, D. W.; Chen, J. L.; Lahn, B. T.

10.1101/2024.06.17.596931 — molecular biology — Posted on 2024-08-04

4537 Hexa-acylated lipopolysaccharides from the gut microbiota enhance cancer immunotherapy responses

Beresford-Jones, B. S.; Sardar, P.; Xia, W.; Shabana, O.; Suyama, S.; Ramos, R. J. J. F.; Soderholm, A. T.; Tourlomousis, P.; Kuo, P.; Evans, A. C.; Imianowski, C. J.; Conti, A. G.; Wesolowski, A. J.; Okkenhaug, K.; Whiteside, S. K.; Roychoudhuri, R.; Bryant, C. E.; Cross, J. R.; Pedicord, V. A.

10.1101/2024.06.24.600291 — microbiology — Posted on 2024-08-04

4538 Hierarchical gradients of multiple timescales in the mammalian forebrain

Song, M.; Shin, E. J.; Seo, H.; Soltani, A.; Steinmetz, N. A.; Lee, D.; Jung, M. W.; Paik, S.-B.

10.1101/2023.05.12.540610 — neuroscience — Posted on 2024-08-04

4539 CBGTPy: An extensible cortico-basal ganglia-thalamic framework for modeling biological decision making

Clapp, M.; Bahuguna, J.; Giossi, C.; Rubin, J.; Verstynen, T. V.; Vich, C.

10.1101/2023.09.05.556301 — neuroscience — Posted on 2024-08-04

4540 Molecular and cellular dynamics of the developing human neocortex at single-cell resolution

Wang, L.; Wang, C.; Moriano, J. A.; Chen, S.; Zuo, G.; Cebrian-Silla, A.; Zhang, S.; Mukhtar, T.; Wang, S.; Song, M.; de Oliveira, L. G.; Bi, Q.; Augustin, J. J.; Ge, X.; Paredes, M. F.; Huang, E. J.; Alvarez-Buylla, A.; Duan, X.; Li, J.; Kriegstein, A. R.

10.1101/2024.01.16.575956 — neuroscience — Posted on 2024-08-04

4541 Parallel reconstruction of the excitatory and inhibitory inputs received by single neurons reveals the synaptic basis of recurrent spiking

Bartram, J.; Franke, F.; Kumar, S. S.; Buccino, A. P.; Xue, X.; Ganswein, T.; Schroter, M.; Kim, T.; Kasuba, K. C.; Hierlemann, A.

10.1101/2023.01.06.523018 — neuroscience — Posted on 2024-08-04

4542 Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

Ishchenko, Y.; Jeng, A. T.; Feng, S.; Nottoli, T.; Manriquez-Rodriguez, C.; Nguyen, K.; Carrizales, M. G.; Vitarelli, M. J.; Corcoran, E. E.; Greer, C. A.; Myers, S. A.; Koleske, A. J.

10.1101/2024.01.05.574442 — neuroscience — Posted on 2024-08-04

4543 Single-nanoparticle electrophoretic mobility determination and trapping using active-feedback 3D tracking

Johnson, A.; Welsher, K.

10.1101/2024.07.08.602591 — biophysics — Posted on 2024-08-04

4544 Visualizing scRNA-Seq Data at Population Scale with GloScope

Wang, H.; Torous, W.; Gong, B.; Purdom, E.

10.1101/2023.05.29.542786 — bioinformatics — Posted on 2024-08-04

4545 Information, certainty, and learning.

Harris, J. A.; Gallistel, C. R.

10.1101/2024.07.31.606111 — animal behavior and cognition — Posted on 2024-08-04

4546 Functional characteristics and computational model of abundant hyperactive loci in the human genome

Hudaiberdiev, S.; Ovcharenko, I.

10.1101/2023.02.05.527203 — genomics — Posted on 2024-08-04

4547 Conservation of dichromatin organization along regional centromeres

10.1101/2023.04.20.537689 — genomics — Posted on 2024-08-04

4548 Positive epistasis for fitness under monosomy: Loss of ribosomal protein stoichiometry reduces the effects of other perturbations

Tutaj, H.; Tomala, K.; Pirog, A.; Marszalek, M.; Korona, R.

10.1101/2023.03.12.532261 — evolutionary biology — Posted on 2024-08-04

4549 Accurate Inference of the Polyploid Continuum using Forward-time Simulations

Dunn, T.; Sethuraman, A.

10.1101/2024.05.17.594724 — evolutionary biology — Posted on 2024-08-04

4550 Disentangling cell-intrinsic and extrinsic factors underlying evolution

Starr, A. L.; Nishimura, T.; Igarashi, K. J.; Funamoto, C.; Nakauchi, H.; Fraser, H.

10.1101/2024.05.06.592777 — evolutionary biology — Posted on 2024-08-04

4551 Antecedent effect models as an exploratory tool to link climate drivers to herbaceous perennial population dynamics data

Compagnoni, A.; Knight, T. M.; Childs, D.; Salguero-Gomez, R.

10.1101/2022.03.11.484031 — ecology — Posted on 2024-08-04

4552 Seed functional ecology in Brazilian rock outcrop vegetation: an integrative synthesis

Ordonez-Parra, C. A.; Medeiros, N. F.; Dayrell, R. L. C.; Le Stradic, S.; Negreiros, D.; Cornelissen, T.; Silveira, F. A. O.

10.1101/2023.03.21.533674 — ecology — Posted on 2024-08-04

4553 Physical modeling of embryonic transcriptomes identifies collective modes of gene expression

Skinner, D.; Lemaire, P.; Mani, M.

10.1101/2024.07.26.605398 — developmental biology — Posted on 2024-08-04

4554 Using machine learning to dissect host kinases required for Leishmania internalization and development

Wei, L.; Barrie, U.; Aloisio, G. M.; Khuong, F. T. H.; Arang, N.; Datta, A.; Kaushansky, A.; Wetzel, D. M.

10.1101/2024.05.16.593986 — microbiology — Posted on 2024-08-04

4555 Nutrient colimitation is a quantitative, dynamic property of microbial populations

Held, N. A.; Krishna, A.; Crippa, D.; Battaje, R. R.; Devaux, A. J.; Dragan, A.; Manhart, M.

10.1101/2023.09.27.559472 — microbiology — Posted on 2024-08-04

4556 Genomic and phenotypic characterization of an Oropouche virus strain implicated in the 2023-24 large-scale outbreak in Brazil

Azevedo, E. A. N.; da Silva, A. F.; da Silva, V. V. G.; Machado, L. C.; de Lima, G. B.; Ishigami, B. I. M.; Silva, K. M. P.; da Costa, M. M. O. M.; Falcao, D. A.; Vasconcelos, A. P.; da Silva, C. C.; Naveca, F. G.; Bezerra, M. F.; Campos, T. L.; Acioli-Santos, B.; Paiva, M. H. S.; Morais, C. N. L.; Wallau, G. d. L.

10.1101/2024.08.02.606252 — microbiology — Posted on 2024-08-04

4557 The expanded immunoregulatory protease network in mosquitoes is governed by gene co-expression

Morejon, B.; Michel, K.

10.1101/2024.06.18.599423 — immunology — Posted on 2024-08-04

4558 A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency

Kuhn, B. N.; Cannella, N.; Crow, A.; Lunerti, V.; Gupta, A.; Walterhouse, S.; Allen, C.; Chalhoub, R.; Dereschewitz, E.; Roberts, A.; Cockerham, M.; Beeson, A.; Nall, R.; Palmer, A. A.; Hardiman, G.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.

10.1101/2024.02.22.581440 — neuroscience — Posted on 2024-08-04

4559 Linalool fumigation improves mating competitiveness of males for population suppression of the global fruit pest Cydia pomonella

Huang, S.-W.; Wang, P.-C.; Wang, Y.; Wang, J.-Q.; Gao, P.; Ji, Q.-E.; Yang, X.

10.1101/2024.07.21.604520 — zoology — Posted on 2024-08-04

4560 A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.

10.1101/2024.02.10.579775 — biophysics — Posted on 2024-08-04

4561 The estrous cycle modulates hippocampal spine dynamics, dendritic processing, and spatial coding

Wolcott, N. S.; Redman, W. T.; Karpinska, M.; Jacobs, E. G.; Goard, M. J.

10.1101/2024.08.02.606418 — neuroscience — Posted on 2024-08-03

4562 A general principle governing neuronal evolution reveals a human-accelerated neuron type potentially underlying the high prevalence of autism in humans

Starr, A. L.; Fraser, H. B.

10.1101/2024.08.02.606407 — neuroscience — Posted on 2024-08-03

4563 Concerted modulation of spontaneous behavior and time-integrated whole-brain neuronal activity by serotonin receptors

Friedmann, D.; Gonzalez, X.; Moses, A.; Watts, T.; Degleris, A.; Ticea, N.; Song, J. H.; Datta, S. R.; Linderman, S. W.; Luo, L.

10.1101/2024.08.02.606282 — neuroscience — Posted on 2024-08-03

4564 Humans use local spectrotemporal correlations to detect rising and falling pitch

Vaziri, P. A.; McDougle, S. D.; Clark, D. A.

10.1101/2024.08.03.606481 — neuroscience — Posted on 2024-08-03

4565 Bezafibrate treatment rescues neurodevelopmental and neurodegenerative defects in 3D cortical organoid model of MAPT frontotemporal dementia

Cordella, F.; Mautone, L.; Tondo, L.; Salerno, D.; Ghirga, S.; Parente, E.; Romeo, M. A.; Cirone, M.; Bezzi, P.; Di Angelantonio, S.

10.1101/2024.08.02.606317 — neuroscience — Posted on 2024-08-03

4566 Structural perturbation of chromatin domains with multiple developmental regulators can severely impact gene regulation and development

Chakraborty, S.; Wenzlitschke, N.; Anderson, M. J.; Eraso, A.; Baudic, M.; Thompson, J. J.; Evans, A. A.; Shatford Adams, L. M.; Chari, R.; Awasthi, P.; Dale, R. K.; Lewandoski, M.; Petros, T. J.; Rocha, P. P.

10.1101/2024.08.03.606480 — developmental biology — Posted on 2024-08-03

4567 Biophysical Simulation Enables Multi-Scale Segmentation and Atlas Mapping for Top-Down Spatial Omics of the Nervous System

Mohammed Ali, L. K.; Yim, A. K. Y.; Nguyen, T.; Tu, N. K.; Gerbi, E. B.; Grigore, D.; Waligorski, J. E.; Kremitzki, C. L.; Mitra, R. D.; Milbrandt, J. D.; Buchser, W. J.

10.1101/2024.08.02.605366 — neuroscience — Posted on 2024-08-03

4568 Acute stress causes sex-dependent changes to ventral subiculum synapses, circuitry, and anxiety-like behavior

Miller, C.; Li, Y.; Beier, K. T.; Aoto, J.

10.1101/2024.08.02.606264 — neuroscience — Posted on 2024-08-03

4569 A map of integrated cis-regulatory elements enhances gene regulatory analysis in maize

Manosalva Perez, N.; Staut, J.; Matres Ferrando, A.; Dissanayake, I.; Vandepoele, K.

10.1101/2024.08.01.606127 — bioinformatics — Posted on 2024-08-03

4570 Computational design of highly active de novo enzymes

Braun, M.; Tripp, A.; Chakatok, M.; Kaltenbrunner, S.; Totaro, M. G.; Stoll, D.; Bijelic, A.; Elaily, W.; Hoch, S. Y. Y.; Aleotti, M.; Hall, M.; Oberdorfer, G.

10.1101/2024.08.02.606416 — biochemistry — Posted on 2024-08-03

4571 Human populations with low survival at advanced ages and postponed fertility reduce long-term growth in high inflation environments

Mondal, R.; Aburto, J. M.; Sear, R.; Tuljapurkar, S. D.; Mishra, U. S.; Salguero-Gomez, R.

10.1101/2024.07.31.606043 — animal behavior and cognition — Posted on 2024-08-03

4572 A causative SNP in the promoter of myogenin is essential for myogenic differentiation

Lin, Z.; Wang, X.; Liang, Z.; Xu, R.; Chen, M.; Tong, X.; Li, C.; Xiong, Y.; Yuan, R.; Chen, Y.; Liu, X.; Zhao, Y.; Mo, D.

10.1101/2024.08.01.606143 — genetics — Posted on 2024-08-03

4573 Dose-dependent regulation of immune memory responses against HIV by saponin monophosphoryl lipid A nanoparticle adjuvant

Ramezani-Rad, P.; Marina-Zarate, E.; Maiorino, L.; Myers, A.; Michaels, K. K.; Pires, I. S.; Bloom, N. I.; Lopez, P. G.; Cottrell, C. A.; Burton, I.; Groschel, B.; Pradhan, A.; Stiegler, G.; Budai, M.; Kumar, D.; Pallerla, S.; Sayeed, E.; Sagar, S. L.; Kasturi, S. P.; Van Rompay, K. K. A.; Hangartner, L.; Wagner, A.; Burton, D. R.; Schief, W. R.; Crotty, S.; Irvine, D. J.

10.1101/2024.07.31.604373 — immunology — Posted on 2024-08-03

4574 Neutralization activity in chronic HIV infection is characterized by a distinct programming of follicular helper CD4 T cells

Moysi, E.; Sharma, A. A.; O'Dell, S.; Georgakis, S.; Del Rio Estrada, P. M.; Torres-Ruiz, F.; Gonzalez Navarro, M.; Luna Villalobos, Y. A.; Avila Rios, S.; Reyes-Teran, G.; Beddall, M. H.; Ko, S.-H.; Belinky, F.; Orfanakis, M.; de Leval, L.; Enriquez, A. B.; Buckner, C. M.; Moir, S.; Doria-Rose, N.; Boritz, E.; Mascola, J. R.; Sekaly, R. P.; Koup, R. A.; Petrovas, C.

10.1101/2024.07.31.605954 — immunology — Posted on 2024-08-03

4575 Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinsons linked-LRRK2 mutant mice

Jaimon, E.; Lin, Y.-E.; Tonelli, F.; Antico, O.; Alessi, D. R.; Pfeffer, S. R.

10.1101/2024.07.31.606089 — neuroscience — Posted on 2024-08-03

4576 Integration of sensory and fear memories in the rat medial temporal lobe

Wong, F. S.; Thomas, A. B.; Killcross, S.; Laurent, V.; Westbrook, R. F.; Holmes, N. M.

10.1101/2024.07.31.605652 — neuroscience — Posted on 2024-08-03

4577 The assembly of Y chromosome reveals amplification of genes regulating male fertility in Bactrocera dorsalis

Wu, S.; Wu, J.; Lei, Q.; He, D.; Jiang, X.; Ye, C.; Wei, D.; Wang, J.-J.; Xu, L.; Jiang, H.

10.1101/2024.08.01.606120 — zoology — Posted on 2024-08-03

4578 Comprehensive transcription factor perturbations recapitulate fibroblast transcriptional states

Southard, K. M.; Ardy, R. C.; Tang, A.; O'Sullivan, D. D.; Metzner, E.; Guruvayurappan, K.; Norman, T. M.

10.1101/2024.07.31.606073 — systems biology — Posted on 2024-08-03

4579 Effects of healthy aging on tongue-jaw kinematics during feeding behavior in rhesus macaques

Punacha, S.; Huang, K.; Arce-McShane, F. I.

10.1101/2024.07.31.605680 — systems biology — Posted on 2024-08-03

4580 Target enrichment phylogenomics and biogeographic analyses unravel rapid radiation and reticulate evolution between Hainan-South China mainland -Vietnam in Section Nintooa (Lonicera, Caprifoliaceae)

Zuo, S.-y.; Sun, Q.-h.; Morales-Briones, D. F.; Landis, J. B.; Li, H.-Y.; Wang, H.-X.; Dong, H.-J.; Wen, J.; Wang, H.-F.

10.1101/2024.08.01.605766 — plant biology — Posted on 2024-08-03

4581 Gene editing of the E3 ligase PIRE1 fine-tunes ROS production for enhanced bacterial disease resistance in tomato

Castro, B.; Baik, S.; Tran, M.; Zhu, J.; Li, T.; Aoun, N.; Blundell, A.; Gomez, M.; Zhang, E.; Cho, M.-J.; Lowe-Power, T.; Siddique, S.; Staskawicz, B.; Coaker, G.

10.1101/2024.07.31.606097 — plant biology — Posted on 2024-08-03

4582 Investigating the links between trifluralin persistence in Western Australian soils and trifluralin resistance in resident annual ryegrass (Lolium rigidum) populations

Goggin, D.; Boyes, T.; Busi, R.; Flower, K.

10.1101/2024.07.31.606087 — plant biology — Posted on 2024-08-03

4583 snRNA-seq analysis of the moss Physcomitrium patens reveals a conserved cytokinin-ESR module promoting pluripotent stem cell identity

Hata, Y.; Hetherington, N.; Battenberg, K.; Hirota, A.; Minoda, A.; Hayashi, M.; Kyozuka, J.

10.1101/2024.07.31.606100 — plant biology — Posted on 2024-08-03

4584 Secreted chemokines reveal diverse inflammatory and degenerative processes in the intervertebral disc of the STZ-HFD mouse model of Type 2 diabetes

Gonzalez, C. E.; Vaidya, R. S.; Clayton, S. W.; Tang, S. Y.

10.1101/2024.07.31.605332 — physiology — Posted on 2024-08-03

4585 Inhibition of Atrial Natriuretic Peptide Clearance Reduces Myocardial Fibrosis and Improves Cardiac Function in Diabetic Rats

Fares, N.; Bakhos, J. J.; Saliba, Y.; Hajal, J.; Achkouty, G.; Oskaridjian, H.; Azevedo, C.; Semaan, A.; Suffee, N.; Balse, E.; Hatem, S. N.

10.1101/2024.08.01.606125 — physiology — Posted on 2024-08-03

4586 tp53 R217H and R242H Mutant Zebrafish Exhibit Dysfunctional p53 Hallmarks and Recapitulate Li-Fraumeni Syndrome Phenotypes

Kobar, K.; Berman, J. N.; Fiene, J. A.; Tuzi, L.; Burnley, E.; Galpin, K. J. C.; Midgen, C.; Laverty, B.; Moksa, M.; Cao, Q.; Subasri, V.; Wen, T. T.; Shlien, A.; Hirst, M.; Malkin, D.; Prykhozhij, S.; Carles, A.

10.1101/2024.07.31.605368 — cancer biology — Posted on 2024-08-03

4587 MOSTPLAS: A Self-correction Multi-label Learning Model for Plasmid Host Range Prediction

Zou, W.; Ji, Y.; Guan, J.; Sun, Y.

10.1101/2024.07.31.606102 — bioinformatics — Posted on 2024-08-03

4588 A Library of Custom PEG-Lipids reveals a Double-PEG-Lipid with Drastically Enhanced Paclitaxel Solubility and Human Cancer Cell Cytotoxicity when used in Fluid Micellar Nanoparticles

Ghasemizadeh, A.; Wan, L.; Hirose, A.; Diep, J.; Ewert, K. K.; Safinya, C. R.

10.1101/2024.08.01.606138 — bioengineering — Posted on 2024-08-03

4589 Along- and cross-muscle fiber shear moduli in skeletal muscle

Sahani, R.; Reyna, W.; Royston, T.; Perreault, E. J.; Ludvig, D.

10.1101/2024.07.31.605692 — bioengineering — Posted on 2024-08-03

4590 Adapting protein language models for structure-conditioned design

Ruffolo, J. A.; Bhatnagar, A.; Beazer, J.; Nayfach, S.; Russ, J.; Hill, E.; Hussain, R.; Gallagher, J.; Madani, A.

10.1101/2024.08.03.606485 — bioengineering — Posted on 2024-08-03

4591 Spatial variability of agricultural soil carbon dioxide and nitrous oxide fluxes: characterization and recommendations from spatially high-resolution, multi-year dataset

Kim, N.; Jang, C.; Yang, W. H.; Guan, K.; DeLucia, E.; Lee, D.

10.1101/2024.08.02.606447 — biochemistry — Posted on 2024-08-03

4592 Distinct microbial communities are linked to organic matter properties in millimetre-sized soil aggregates

Simon, E.; Guseva, K.; Darcy, S.; Alteio, L.; Pjevac, P.; Schmidt, H.; Jenab, K.; Ranits, C.; Kaiser, C.

10.1101/2024.08.01.606122 — ecology — Posted on 2024-08-03

4593 Optogenetic control of phosphate-responsive genes using single component fusion proteins in Saccharomyces cerevisiae

Cleere, M. M.; Gardner, K. H.

10.1101/2024.08.02.605841 — molecular biology — Posted on 2024-08-03

4594 Respiratory Syncytial Virus (RSV) optimizes the translational landscape during infection

Kerkhofs, K.; Guydosh, N. R.; Bayfield, M. A.

10.1101/2024.08.02.606199 — molecular biology — Posted on 2024-08-03

4595 A comprehensive genetic catalog of human double-strand break repair

Lopez de Alba, E.; Salguero, I.; Gimnez-Llorente, D.; Fernandez-Sanroman, A.; Casajus-Pelegay, E.; Terron-Bautista, J.; Barroso-Gonzalez, J.; Bernal, J. A.; Macintyre, G.; Fernandez-Leiro, R.; Losada, A.; Cortes-Ledesma, F.

10.1101/2024.08.03.606369 — molecular biology — Posted on 2024-08-03

4596 Unraveling the Molecular mechanism of Polysaccharide Lyases for Efficient Alginate Degradation

Rivas-Fernandez, J. P.; Vuillemin, M.; Pilgaard, B.; J. Klau, L.; Fredslund, F.; Lund-Hanssen, C.; H. Welner, D.; S. Meyer, A.; Morth, J. P.; Meilleur, F.; L. Aachmann, F.; Rovira, C.; Wilkens, C.

10.1101/2024.08.02.606366 — molecular biology — Posted on 2024-08-03

4597 A versatile dual reporter to identify ribosome pausing motifs alleviated by translation elongation factor P

Tomasiunaite, U.; Brewer, T.; Burdack, K.; Brameyer, S.; Jung, K.

10.1101/2024.08.03.606492 — molecular biology — Posted on 2024-08-03

4598 Landscape of Differentiation Potentials as a "Hallmark" in Oral-derived MSCs

Chopra, H.; Cao, C.; Herrmann, A.; Kak, S.; Maska, B.; Tagett, R.; Garmire, L.; Sugai, J.; Kaigler, D.

10.1101/2024.08.02.606413 — molecular biology — Posted on 2024-08-03

4599 Isolation and characterization of mollicute symbionts from a fungus-growing ant reveals genome reduction and host specialization

Green, E. A.; Klepacki, I.; Klassen, J. L.

10.1101/2024.08.02.606451 — microbiology — Posted on 2024-08-03

4600 Untrimmed ITS2 metabarcode sequences cause artificially reduced abundances of specific fungal taxa

Kyle, K. E.; Klassen, J. L.

10.1101/2024.08.02.606430 — microbiology — Posted on 2024-08-03

4601 A machine learning approach reveals that spore levels in organic bulk tank milk are dependent on farm characteristics and meteorological factors

Qian, C.; Lee, R. T.; Weachock, R. L.; Wiedmann, M.; Martin, N. H.

10.1101/2024.08.03.606478 — microbiology — Posted on 2024-08-03

4602 The study on the impact of indoleacetic acid on enhancing the ability of the rumen's original microecology to degrade aflatoxin B1.

Guo, G.; Sun, J.; wang, z.; Yan, X.; Zhao, Y.; Tan, L.; Miao, X.; Zhao, R.; Huo, W.; Chen, L.; Li, Q.; Liu, Q.; Wang, C.

10.1101/2024.08.02.606440 — microbiology — Posted on 2024-08-03

4603 A targeted CRISPR screen identifies ETS1 as a regulator of HIV latency.

Ashokkumar, M.; Hafer, T. L.; Felton, A.; Archin, N.; Margolis, D. M.; Emerman, M.; Browne, E. P.

10.1101/2024.08.03.606477 — microbiology — Posted on 2024-08-03

4604 Gut Microbiome Perturbation Affected Conjugative Transfer of Antimicrobial Resistance Genes

Yilmaz, G.; Chan, M.; Lau, C. H.-F.; Capitani, S.; Kang, M.; Charron, P.; Hoover, E.; Topp, E.; Guan, J.

10.1101/2024.08.03.605226 — microbiology — Posted on 2024-08-03

4605 An engineered prodrug selectively suppresses β-lactam resistant bacteria in a mixed microbial setting

Duda, A. M.; Ma, H. R.; Villalobos, C. A.; Kuhn, S. A.; He, K.; Seay, S. R.; Jackson, A. C.; Suh, C. M.; Puccio, E. A.; Anderson, D. A.; Fowler, V. G.; You, L.; Franz, K. J.

10.1101/2024.08.02.606422 — microbiology — Posted on 2024-08-03

4606 Enhanced replication of contemporary human highly pathogenic avian influenza H5N1 virus isolate in human lung organoids compared to bovine isolate

Flagg, M.; Williamson, B. N.; Ortiz-Morales, J. A.; Lutterman, T.; de Wit, E.

10.1101/2024.08.02.606417 — microbiology — Posted on 2024-08-03

4607 Lack of pathogenic involvement of CCL4 and its receptor CCR5 in arthritogenic alphavirus disease

Hameed, M.; A. Solomon, N.; Weger-Lucarelli, J.

10.1101/2024.07.31.606106 — immunology — Posted on 2024-08-03

4608 Engineered prime editors with minimal genomic errors

Chauhan, V. P.; Sharp, P. A.; Langer, R.

10.1101/2024.08.02.606370 — bioengineering — Posted on 2024-08-03

4609 Engineering ionizable lipids for rapid biodegradation balances mRNA vaccine efficacy and tolerability

Couture-Senecal, J.; Tilstra, G.; Khan, O. F.

10.1101/2024.08.02.606386 — bioengineering — Posted on 2024-08-03

4610 Modeling glioblastoma tumor progression via CRISPR-engineered brain organoids

Ishahak, M.; Han, R. H.; Annamalai, D.; Woodiwiss, T.; McCornack, C.; Cleary, R. T.; DeSouza, P. A.; Qu, X.; Dahiya, S.; Kim, A. H.; Millman, J. R.

10.1101/2024.08.02.606387 — bioengineering — Posted on 2024-08-03

4611 Generation of antagonistic biparatopic anti-CD30 antibody from an agonistic antibody by precise epitope determination and utilization of structural characteristics of CD30 molecule

Akiba, H.; Ise, T.; Satoh, R.; Abe, Y.; Tsumoto, K.; Ohno, H.; Kamada, H.; Nagata, S.

10.1101/2024.08.02.606455 — biochemistry — Posted on 2024-08-03

4612 Degradation in Binaural and Spatial Hearing and Auditory Temporal Processing Abilities as a Function of Aging

Sammeth, C. A.; Walker, K. A.; Greene, N. T.; Klug, A.; Tollin, D.

10.1101/2024.07.08.602575 — neuroscience — Posted on 2024-08-03

4613 Membrane bound geranylated RNAs establish a primitive peptide synthesis system

Chan, C. Y.; Singer, J. N.; Carell, T.

10.1101/2024.08.02.606298 — molecular biology — Posted on 2024-08-03

4614 High-capacity flexible hippocampal associative and episodic memory enabled by prestructured "spatial" representations

Chandra, S.; Sharma, S.; Chaudhuri, R.; Fiete, I.

10.1101/2023.11.28.568960 — neuroscience — Posted on 2024-08-03

4615 Multiple Protein Structure Alignment at Scale with FoldMason

Gilchrist, C. L. M.; Mirdita, M.; Steinegger, M.

10.1101/2024.08.01.606130 — bioinformatics — Posted on 2024-08-03

4616 CryoSamba: self-supervised deep volumetric denoising for cryo-electron tomography data

Costa-Filho, J. I.; Theveny, L.; de Sautu, M.; Kirchhausen, T.

10.1101/2024.07.11.603117 — bioinformatics — Posted on 2024-08-03

4617 A rapid phylogeny-based method for accurate community profiling of large-scale metabarcoding datasets

Pipes, L.; Nielsen, R.

10.1101/2022.12.06.519402 — genomics — Posted on 2024-08-03

4618 Environmental variability can promote parasite diversity within hosts and transmission among hosts

Jarvis-Cross, M.; Krkosek, M.

10.1101/2023.06.05.543787 — ecology — Posted on 2024-08-03

4619 A microglia clonal inflammatory disorder in Alzheimer's Disease

Vicario, R.; Fragkogianni, S.; Weber, L.; Lazarov, T.; Hu, Y.; Hayashi, S. Y.; Craddock, B. P.; Socci, N. D.; Alberdi, A.; Baako, A.; Ay, O.; Ogishi, M.; Lopez-Rodrigo, E.; Kappagantula, R.; Viale, A.; Iacobuzio-Donahue, C. A.; Zhou, T.; Ransohoff, R. M.; Chesworth, R.; Netherlands Brain Bank, ; Abdel-Wahab, O.; Boisson, B.; Elemento, O.; Casanova, J.-L.; Miller, W. T.; Geissmann, F.

10.1101/2024.01.25.577216 — neuroscience — Posted on 2024-08-03

4620 STEMorph: A Set of Morphed Emotional Face Stimuli from Angry to Happy Derived from NimStim

Katebi, M. E.; Ghafari, M. H.; Ghafari, T.

10.1101/2024.05.13.593881 — neuroscience — Posted on 2024-08-03

4621 Sequential transcriptional waves and NF-κB-driven chromatin remodeling direct drug-induced dedifferentiation in cancer

Su, Y.; Liu, C.; Lu, X.; Li, G.; Shao, S.; Kong, Y.; Lee, J.; Ng, R.; Wong, S.; Robert, L.; Warden, C.; Liu, V.; Chen, J.; Wang, Z.; Qin, G.; Tang, Y.; Cheng, H.; Ng, A.; Peng, S.; Xue, M.; Johnson, D.; Xu, Y.; Wang, J.; Wu, X.; Shmulevich, I.; Shi, Q.; Levine, R.; Ribas, A.; Baltimore, D.; Guo, J.; Heath, J. R.; Wei, W.

10.1101/724740 — cancer biology — Posted on 2024-08-03

4622 Persistence of alternative reproductive tactics: a test of game theoretic predictions

Garrison, C. R.; Sakaluk, S.; Dochtermann, N.

10.1101/2020.06.17.157727 — animal behavior and cognition — Posted on 2024-08-03

4623 Optogenetic hedonic hotspots in orbitofrontal cortex and insula: causing enhancement of sweetness liking

Morales, I.; Berridge, K. C.

10.1101/2024.07.31.606067 — neuroscience — Posted on 2024-08-03

4624 An EYA3/NF-κB/CCL2 signaling axis suppresses cytotoxic NK cells in the pre-metastatic niche to promote triple negative breast cancer metastasis

Rosenbaum, S. R.; Hughes, C. J.; Fields, K. M.; Purdy, S. C.; Gustafson, A.; Wolin, A.; Hampton, D.; Turner, N.; Ebmeier, C. C.; Costello, J. C.; Ford, H. L.

10.1101/2024.07.31.606072 — cancer biology — Posted on 2024-08-03

4625 Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer

Havas, A.; Lande, K.; Rajesh, A.; Evensen, K. G.; Varanasi, S. K.; Shang, L.; Schmidt, E.; Lee, J.; Kim, K.; Teneche, M. G.; Hoffmann, F.; LaPorte, M.; Davis, A.; Grier, A.; Reisz, J. A.; Tharp, K.; Gandhi, A.; Lei, X.; Proulx, J.; Miller, K. N.; Sacco, A.; Shadel, G. S.; Niedernhofer, L.; Feng, G.-S.; D'Alesssandro, A.; Kaech, S.; Williams, A.; Adams, P. D.

10.1101/2024.07.31.606057 — cancer biology — Posted on 2024-08-03

4626 PAX fusion proteins deregulate gene networks controlling mitochondrial translation in pediatric rhabdomyosarcoma

Kalita, B.; Martinez-Cebrian, G.; McEvoy, J.; Allensworth, M.; Knight, M.; Magli, A.; Perlingeiro, R. C. R.; Dyer, M. A.; Stewart, E. A.; Dynlacht, B. D.

10.1101/2024.07.31.606039 — cancer biology — Posted on 2024-08-03

4627 Bootstrap Evaluation of Association Matrices (BEAM) for Integrating Multiple Omics Profiles with Multiple Outcomes

Seffernick, A. E.; Cao, X.; Cheng, C.; Yang, W.; Autry, R. J.; Yang, J. J.; Pui, C.-H.; Teachey, D. T.; Lamba, J. K.; Mullighan, C. G.; Pounds, S. B.

10.1101/2024.07.31.605805 — bioinformatics — Posted on 2024-08-03

4628 Predatory aggression evolved through adaptations to noradrenergic circuits

Eren, G. G.; Boger, L.; Roca, M.; Hiramatsu, F.; Liu, J.; Alvarez, L.; Goetting, D. L.; Zorn, N.; Han, Z.; Okumura, M.; Scholz, M.; Lightfoot, J. W.

10.1101/2024.08.02.606321 — animal behavior and cognition — Posted on 2024-08-02

4629 Effects of short-term isolation on vocal and non-vocal social behaviors in prairie voles

Madrid, J. E.; Pranic, N. M.; Chu, S.; Bergstrom, J. J. D.; Singh, R.; Rabinovich, J.; Lopez, K. A.; Ophir, A. G.; Tschida, K. A.

10.1101/2024.08.02.605822 — animal behavior and cognition — Posted on 2024-08-02

4630 Autophagy disruption and mitochondrial stress precede photoreceptor necroptosis in multiple mouse models of inherited retinal disorders.

Newton, F.; Halachev, M.; Nguyen, L.; McKie, L.; Mill, P.; Megaw, R.

10.1101/2024.08.02.606303 — cell biology — Posted on 2024-08-02

4631 Uncovering Individualized Cerebellar Atrophy Pattern and Behavioral Links in Children with Brainstem Tumor

Jia, H.; Wang, K.; Zhang, M.; Gu, G.; Mai, Y.; Wu, X.; Chu, C.; Yin, X.; Zhang, P.; Fan, L.; Zhang, L.

10.1101/2024.08.01.606261 — neuroscience — Posted on 2024-08-02

4632 Co-activation of LIN28A and CTNNB1 disturbs cortical neuronal migration and pia mater integrity

Navolic, J.; Hawass, S.; Moritz, M.; Hahn, J.; Middelkamp, M.; Gocke, A.; Dottermusch, M.; Schumann, Y.; Ruck, L.; Krisp, C.; Godbole, S.; Sumislawski, P.; Schlueter, H.; Neumann, J. E.

10.1101/2024.08.01.606182 — neuroscience — Posted on 2024-08-02

4633 Distinct neuromodulatory effects of endogenous orexin and dynorphin corelease on projection-defined ventral tegmental dopamine neurons.

Mohammadkhani, A.; Qiao, M.; Borgland, S. L.

10.1101/2024.08.01.606179 — neuroscience — Posted on 2024-08-02

4634 Word-selective EEG/MEG responses in the English language obtained with Fast Periodic Visual Stimulation (FPVS)

Hauk, O.; Marchive, M.; Volfart, A.; Schiltz, C.; Rossion, B.; Lambon Ralph, M. A.; Lochy, A.

10.1101/2024.08.02.606349 — neuroscience — Posted on 2024-08-02

4635 A modified dual preparatory method for improved isolation of nucleic acids from laser microdissected fresh-frozen human cancer tissue specimens

Kimble, D. C.; Litzi, T. J.; Snyder, G.; Olowu, V.; TaQee, S.; Conrads, K. A.; Loffredo, J.; Bateman, N. W.; Alba, C.; Rice, E.; Shriver, C. D.; Maxwell, G. L.; Dalgard, C.; Conrads, T. P.

10.1101/2024.08.02.606193 — biochemistry — Posted on 2024-08-02

4636 Biased estimates of phylogenetic branch lengths resulting from the discretised Gamma model of site rate heterogeneity

Ferretti, L.; Golubchik, T.; Di Lauro, F.; Ghafari, M.; Villabona-Arenas, J.; Atkins, K. E.; Fraser, C.; Hall, M. D.

10.1101/2024.08.01.606208 — evolutionary biology — Posted on 2024-08-02

4637 Development of a latency model based on HIV-1 subtype C to study how long terminal repeat genetic variation impacts viral persistence and latency reversal

Madlala, P.; Maikoo, S.; Palstra, R.-J.; Dong, K. L.; Mahmoudi, T.; Ndung'u, T.

10.1101/2024.08.02.606371 — molecular biology — Posted on 2024-08-02

4638 Membrane bound geranylated RNAs establish a primitive peptide synthesis system

Chan, C. Y.; Singer, J. N.; Carell, T.

10.1101/2024.08.02.606298 — molecular biology — Posted on 2024-08-02

4639 Monoacylglycerol acyltransferase maintains ionotropic receptor expression for cool temperature sensing and avoidance in Drosophila

DENG, X.; SUITO, T.; TOMINAGA, M.; SOKABE, T.

10.1101/2024.08.02.606314 — molecular biology — Posted on 2024-08-02

4640 Targeting of retrovirus-derived Rtl8a/8b reduces social response and increases apathy-like behavior associated with GABRB2 reduction

Fujioka, Y.; Shiura, H.; Ishii, M.; Ono, R.; Endo, T.; Kiyonari, H.; Hirate, Y.; Ito, H.; Azuma-Kanai, M.; Kohda, T.; Kaneko-Ishino, T.; Ishino, F.

10.1101/2024.08.02.606341 — molecular biology — Posted on 2024-08-02

4641 Genomic and phenotypic characterization of an Oropouche virus strain implicated in the 2023-24 large-scale outbreak in Brazil

Azevedo, E. A. N.; da Silva, A. F.; da Silva, V. V. G.; Machado, L. C.; de Lima, G. B.; Silva, K. M. P.; da Costa, M. M. O. M.; Falcao, D. A.; Vasconcelos, A. P.; da Silva, C. C.; Naveca, F. G.; Bezerra, M. F.; Campos, T. L.; Acioli-Santos, B.; Paiva, M. H. S.; Morais, C. N. L.; Wallau, G. d. L.

10.1101/2024.08.02.606252 — microbiology — Posted on 2024-08-02

4642 Identification of anthelmintic activity in a small chemical library through random screening using the worm Caenorhabditis elegans as a model helminth

Gajera, G.; Kothari, V.

10.1101/2024.08.02.606330 — microbiology — Posted on 2024-08-02

4643 Dysbiosis-associated gut bacterium Ruminococcus gnavus varies at the strain level in ability to utilize key mucin component sialic acid

Sokolovskaya, O. M.; Uzunovic, J.; Peng, Y.; Okumura, M.; Wang, L. M.; Zhou, Y.; Lai, Z.; Skippington, E.; Tan, M.-W.

10.1101/2024.08.02.604340 — microbiology — Posted on 2024-08-02

4644 Dysregulation of cholesterol and bile acid homeostasis across the gut-liver axis following Cryptosporidium intestinal infection

Wang, S.; Gong, A.-Y.; Barker, E.; Williams, D. L.; Forsyth, C.; Yu, L.; Chen, X.-M.

10.1101/2024.08.01.606233 — microbiology — Posted on 2024-08-02

4645 E2F3-dependent activation of FAM111B restricts mouse cytomegalovirus replication in primate cells

Ostermann, E.; Luoto, L.-M.; Clausen, M.; Virdi, S.; Brune, W.

10.1101/2024.08.02.606359 — microbiology — Posted on 2024-08-02

4646 Cross-feeding options define eco-evolutionary dynamics of deep oligotrophic groundwater microbiome

Rezaei Somee, M.; Gonzalez-Rosales, C.; Gralka, M.; Turner, S.; Bertilsson, S.; Dopson, M.; Mehrshad, M.

10.1101/2024.08.02.606368 — microbiology — Posted on 2024-08-02

4647 Roles of PknB and CslA in cell wall morphogenesis of Streptomyces

Derkacz, M.; Watson, A.; Gajbhiye, A.; Jakimowicz, D.; Trost, M.; Errington, J.; Kepplinger, B.

10.1101/2024.08.02.606377 — microbiology — Posted on 2024-08-02

4648 Clearing the air on pollutant disruptions of the gut-brain axis: Developmental exposure to Benzopyrene disturbs zebrafish behavior and the gut microbiome in adults and subsequent generations

Alexiev, A.; Stretch, E.; Kasschau, K. D.; Wilson, L. B.; Truong, L.; Tanguay, R. L.; Sharpton, T. J.

10.1101/2024.08.01.606028 — microbiology — Posted on 2024-08-02

4649 WITHDRAWN: Mechanistic modelling of Mycobacterium Tuberculosis beta carbonic anhydrase 3 inhibitors

Manaithiya, A.; Bhowmik, R.; Ray, R.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.

10.1101/2024.04.30.591915 — bioinformatics — Posted on 2024-08-02

4650 Thermodynamic modeling of Csr/Rsm- RNA interactions capture novel, direct binding interactions across the Pseudomonas aeruginosa transcriptome

Lukasiewicz, A. J.; Leistra, A. N.; Hoefner, L.; Monzon, E.; Gode, C. J.; Zorn, B. T.; Janssen, K. H.; Yahr, T. L.; Wolfgang, M. C.; Contreras, L. M.

10.1101/2024.08.01.606018 — bioinformatics — Posted on 2024-08-02

4651 Structural mechanism of MUC5AC mucin net-like polymer formation and its SNP variability that affect risk of the lung diseases COPD and IPF

Trillo-Muyo, S.; Anna, E.; Magnusson, J. M.; Hansson, G. C.

10.1101/2024.08.02.606332 — biochemistry — Posted on 2024-08-02

4652 The phage protein paratox is a multifunctional metabolic regulator of Streptococcus

Muna, T. H.; Rutbeek, N. R.; Horne, J.; Lao, Y. W.; Krokhin, O. V.; Prehna, G.

10.1101/2024.08.02.605684 — biochemistry — Posted on 2024-08-02

4653 Ordering molecular diversity in untargeted metabolomics via molecular community networking

Coler, E. A.; Melnik, A.; Lotfi, A.; Moradi, D.; Ahiadu, B.; Portal Gomes, P. W.; Patan, A.; Dorrestein, P. C.; Barnes, S.; Boginski, V.; Semenov, A.; Aksenov, A. A.

10.1101/2024.08.02.606356 — biochemistry — Posted on 2024-08-02

4654 Evaluation of vectors for gene expression in Pseudovibrio bacteria and their application in Aplysina marine sponge studies

Dai, Y.; Pita, L.; Eustaquio, A. S.

10.1101/2024.08.01.606211 — genetics — Posted on 2024-08-02

4655 The Streptococcus agalactiae LytSR two-component regulatory system promotes vaginal colonisation and virulence in vivo

AlQadeeb, H.; Baltazar, M.; Cazares, A.; Poonpanichakul, T.; Kjos, M.; French, N.; Kadioglu, A.; O'Brien, M.

10.1101/2024.08.02.606384 — microbiology — Posted on 2024-08-02

4656 Endocytic dynamin deficiency impairs the host colonization of phytopathogenic fungi

Chen, X.; Chen, X.; Long, Y.; Fang, Z.; Abubakar, Y. S.; Zheng, H.; Wang, Z.; Zheng, W.

10.1101/2024.08.02.606287 — microbiology — Posted on 2024-08-02

4657 A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole of Chlamydia trachomatis

Babu Sait, M. R.; Jachmann, L. H.; Milivojevic, M.; Llorente-Saez, C.; Dhanjal, S.; Schumacher, F.; Henriksson, S.; Gayathri Vegesna, N. V.; Chaban, A.; Mohanty, P.; Ölander, M.; Muraleedharan, S.; Farmand Azadeh, S.; Kleuser, B.; Schmierer, B.; Sixt, B. S.

10.1101/2024.08.02.606337 — microbiology — Posted on 2024-08-02

4658 Impact of commercial gut health interventions on caecal metagenome and broiler performance

Pangga, G. M. V.; Star-Shirko, B.; Psifidi, A.; Xia, D.; Corcionivoschi, N.; Kelly, C.; Hughes, C.; Lavery, U.; Richmond, A.; Ijaz, U. Z.; Gundogdu, O.

10.1101/2024.08.02.606333 — microbiology — Posted on 2024-08-02

4659 SIP2 functions as the master transcription factor of the Plasmodium merozoite formation

Nishi, T.; Kaneko, I.; Yuda, M.

10.1101/2024.08.02.606280 — microbiology — Posted on 2024-08-02

4660 Recycling of trans-Golgi SNAREs is essential for apoplastic effector secretion and effective pathogenicity of Magnaporthe oryzae

Lin, L.; Wu, Q.; Wang, S.; Gong, Q.; Huang, X.; Abubakar, Y. S.; Liu, Y.; Cao, J.; Hu, J.; Wang, Z.; Lu, G.; Zheng, W.

10.1101/2024.08.02.606313 — microbiology — Posted on 2024-08-02

4661 Microplastics as a novel substrate for antimicrobial resistance: Effects of concentration, composition, and size on E. coli multidrug resistance

Gross, N.; Muhvich, J.; Ching, C.; Gomez, B.; Nahum, Y.; Zaman, M. H.

10.1101/2024.08.01.606221 — microbiology — Posted on 2024-08-02

4662 Using virtual patient cohorts to uncover immune response differences in cancer and immunosuppressed COVID-19 patients

Gazeau, S.; Deng, X.; Brunet-Ratnasingham, E.; Kaufmann, D. E.; Larochelle, C.; Morel, P. A.; Heffernan, J. M.; Davis, C. L.; Smith, A. M.; Jenner, A. L.; Craig, M.

10.1101/2024.08.01.605860 — immunology — Posted on 2024-08-02

4663 Sulfoglycodendron Antivirals with Scalable Architectures and Activities

KRAL, P.; Coppola, F.; Jafari, R.; McReynolds, K. D.

10.1101/2024.08.01.606251 — pharmacology and toxicology — Posted on 2024-08-02

4664 WITHDRAWN: Multimolecular feature-based machine learning: system biology enhanced RF-QSAR modeling for the efficient prediction of the inhibitory potential of diverse SARS CoV-2 3CL Protease inhibitors

Manaithiya, A.; Bhowmik, R.; Ray, R.; Kumar, S.; Sharma, S.; Mathew, B.; Gong, W.; Parkkila, S.; Aspatwar, A.

10.1101/2024.04.30.591922 — bioinformatics — Posted on 2024-08-02

4665 Nanopore-based analysis unravels the genetic landscape and phylogenetic placement of human-infecting Trichuris species in Cote d'Ivoire, Tanzania, Uganda, and Laos

Rahman, N.; Bär, M. A.; Dommann, J.; Hürlimann, E.; Coulibaly, J. T.; Ali, S.; Sayasone, S.; Beinamaryo, P.; Keiser, J.; Schneeberger, P. H. H.

10.1101/2024.07.31.605962 — genomics — Posted on 2024-08-02

4666 Genetic diversity and antimicrobial resistance of Campylobacter jejuni isolates from Gambian children under five with moderate-to-severe diarrhoea and healthy Controls

Betts, M.; Dione, M.; Ikumapayi, U. N.; Senghore, M.; Lamin, M.; Foster-Nyarko, E.; Jaffali, J.; Panchalingam, S.; Nataro, J. P.; Kotloff, K. L.; Levine, M. M.; Saha, D.; Hossain, J. M.; Kwambana-Adams, B.; Antonio, M.

10.1101/2024.07.30.605890 — microbiology — Posted on 2024-08-02

4667 Bovine H5N1 influenza virus binds poorly to human-type sialic acid receptors

Santos, J. J. S.; Wang, S.; McBride, R.; Zhao, Y.; Paulson, J. C.; Hensley, S. E.

10.1101/2024.08.01.606177 — microbiology — Posted on 2024-08-02

4668 The Body Mirroring Thought: The Relationship Between Thought Transitions and Fluctuations in Autonomic Nervous Activity Mediated by Interoception

Sakuragi, M.; Shinagawa, K.; Terasawa, Y.; Umeda, S.

10.1101/2024.07.30.605929 — neuroscience — Posted on 2024-08-02

4669 Unraveling the Neural Landscape of Mental Disorders using Double Functional Independent Primitives (dFIPs)

Soleimani, N.; Iraji, A.; Pearlson, G. D.; Preda, A.; Calhoun, V.

10.1101/2024.08.01.606076 — neuroscience — Posted on 2024-08-02

4670 Resveratrol targets G-quadruplexes to exert its pharmacological effects

Soriano-Lerma, A.; Sanchez-Martin, V.; Murciano-Calles, J.; Ortiz-Gonzalez, M.; Tello-Lopez, M. J.; Perez-Carrasco, V.; Linde-Rodriguez, A.; Ramirez-Macias, I.; Gomez-Pinto, I.; Lopez-Aliaga, I.; Soriano, M.; Garcia-Salcedo, J. A.

10.1101/2024.07.29.605564 — physiology — Posted on 2024-08-02

4671 Development and application of species ID and insecticide resistance assays, for monitoring sand fly Leishmania vectors in the Mediterranean basin and in the Middle East

Balaska, S.; Khajehali, J.; Mavridis, K.; Akiner, M.; Papapostolou, K. M.; Remadi, L.; Kioulos, I.; Miaoulis, M.; Fotakis, E. A.; Chaskopoulou, A.; Vontas, J.

10.1101/2024.07.30.605769 — pharmacology and toxicology — Posted on 2024-08-02

4672 Integrative analysis of patient-derived tumoroids and ex vivo organoid modeling of ARID1A loss in bladder cancer reveals therapeutic molecular targets

Scholtes, M. P.; Akbarzadeh, M.; Nakauma-Gonzales, J. A.; Galaras, A.; Bazrafshan, A.; Torenvliet, B.; Beikmohammadi, L.; Lozovanu, V.; Romal, S.; Moulos, P.; Kan, T. W.; Algoe, M.; van Royen, M. E.; Sachetti, A.; van den Bosch, T. P. P.; Eussen, B.; de Klein, A.; van Leenders, G. J. L. H.; Boormans, J. L.; Hatzis, P.; Palstra, R.-J.; Zuiverloon, T. C. M.; Mahmoudi, T.

10.1101/2024.07.29.601702 — cancer biology — Posted on 2024-08-02

4673 Assessing the ability of ChatGPT to extract natural product bioactivity and biosynthesis data from publications

Kalmer, T. L.; Ancajas, C. M. F.; Cheng, Z.; Oyedele, A. S.; Davis, H. L.; Walker, A.

10.1101/2024.08.01.606186 — bioinformatics — Posted on 2024-08-02

4674 Genome-Wide Analysis of TCP Family Genes and Their Constitutive Expression Pattern Analysis in the Melon (Cucumis melo)

Jone, M. J. H.; Siddique, M. N. A.; Biswas, M. K.; Hossain, M. R.

10.1101/2024.07.30.605410 — bioinformatics — Posted on 2024-08-02

4675 Inferring polygenic negative selection underlying an individual trait as a distribution of fitness effects (DFEs) from GWAS summary statistics

Xue, A. T.; Huang, Y.-f.; Siepel, A.

10.1101/2024.07.29.601707 — evolutionary biology — Posted on 2024-08-02

4676 Variable prevalence of protective Spiroplasma infection over time in two natural populations of Drosophila hydei

Jones, J. E.; Court, R.; Kageyama, D.; Obbard, D. J.; Hurst, G. D. D.

10.1101/2024.07.31.606006 — ecology — Posted on 2024-08-02

4677 Ecology and abundant occurrence of Genea (Pyronemataceae) in western Oregon, U.S.A.

Dawson, H. R.; Dawson, H. A.

10.1101/2024.07.29.604843 — ecology — Posted on 2024-08-02

4678 Perceived and observed biases within scientific communities: a case study in movement ecology

Shaw, A. K.; Fouda, L.; Mezzini, S.; Kim, D.; Chatterjee, N.; Wolfson, D.; Abrahms, B.; Attias, N.; Beardsworth, C. E.; Beltran, R.; Binning, S. A.; Blincow, K. M.; Chan, Y.-C.; Fronhofer, E. A.; Hegemann, A.; Hurme, E. R.; Iannarilli, F.; Kellner, J. B.; McCoy, K. D.; Rafiq, K.; Saastamoinen, M.; Sequeira, A. M. M.; Serota, M. W.; Sumasgutner, P.; Tao, Y.; Torstenson, M.; Yanco, S. W.; Beck, K. B.; Bertram, M. G.; Beumer, L. T.; Bradaric, M.; Clermont, J.; Ellis-Soto, D.; Faltusova, M.; Fieberg, J.; Hall, R. J.; Kolzsch, A.; Lai, S.; Lee-Cruz, L.; Loretto, M.-C.; Loveridge, A.; Michelangeli,

10.1101/2024.07.29.605602 — ecology — Posted on 2024-08-02

4679 Identification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle

Ariyasinghe, N. R.; Gupta, D.; Escopete, S.; Stotland, A. B.; Sundararaman, N.; Ngu, B.; Dabke, K.; Rai, D.; McCarthy, L.; de Souza Santos, R.; McCain, M. L.; Sareen, D.; Parker, S. J.

10.1101/2024.07.30.605659 — molecular biology — Posted on 2024-08-02

4680 Withania somnifera root extract (LongeFera-TM) confers beneficial effects on health and lifespan of the model worm Caenorhabditis elegans

Thakkar, N.; Gajera, G.; Mehta, D.; Nair, S.; Kothari, V.

10.1101/2024.08.01.606126 — molecular biology — Posted on 2024-08-02

4681 First Report of Nipah virus shed in urine by fruit bats (Pteropus medius), Sri Lanka

Kohl, C.; Siriwardana, S.; Muzeniek, T.; Perera, T.; Bas, D.; Oeruc, M.; Brinkmann, A.; Becker-Ziaja, B.; Schwarz, F.; Jeevatharan, H.; Weerasena, J.; Hadunnetti, S.; Perera, I.; Premawansa, G.; Premawansa, S.; Yapa, W.; Nitsche, A.

10.1101/2024.07.31.605971 — microbiology — Posted on 2024-08-02

4682 KLHDC7B as a Potential Therapeutic Target in Systemic Lupus Erythematosus: Insights from Bulk and Single-Cell RNA-Seq and Spatial Transcriptomics of Epidermal Keratinocytes

Guo, S.

10.1101/2024.07.24.604953 — immunology — Posted on 2024-08-02

4683 Augmenting complex and dynamic performance through mindfulness-based cognitive training: an investigation of on-task EEG dynamics.

Dziego, C. A.; Bornkessel-Schlesewsky, I.; Immink, M. A.; Cross, Z. R.; Schlesewsky, M.

10.1101/2024.07.29.605541 — neuroscience — Posted on 2024-08-02

4684 Normative Growth Modeling of Cortical Thickness Identify Neuroanatomical Variability and Distinct Subtypes in Brainstem Tumor Patients

Jia, H.; Wang, K.; Zhang, P.; Zhang, M.; Mai, Y.; Chu, C.; Yin, X.; Fan, L.; Zhang, L.

10.1101/2024.08.01.606270 — neuroscience — Posted on 2024-08-02

4685 Reducing maladaptive behavior in neuropsychiatric disorders using network modification

Timme, N.

10.1101/2024.08.02.606383 — neuroscience — Posted on 2024-08-02

4686 Inhibitory mechanisms in the prefrontal-cortex differentially mediate Putamen activity during valence-based learning

Finkelman, T.; Aberg, K. C.; Furman-Haran, E.; Paz, R.; Tal, A.

10.1101/2024.07.29.605168 — neuroscience — Posted on 2024-08-02

4687 Accelerated enzyme engineering by machine-learning guided cell-free expression

Landwehr, G. M.; Bogart, J. W.; Magalhaes, C.; Hammarlund, E.; Karim, A. S.; Jewett, M. C.

10.1101/2024.07.30.605672 — synthetic biology — Posted on 2024-08-02

4688 Biological changes, political ideology, and scientific communication shape human perceptions of pollen seasons

Song, Y.; Millard-Ball, A.; Fox, N.; Van Berkel, D.; Agrawal, A.; Zhu, K.

10.1101/2024.07.30.605525 — scientific communication and education — Posted on 2024-08-02

4689 An updated and expanded characterization of the biological sciences academic job market

Flynn, B.; Kozik, A. J.; Cheng, Y.; Haagan, A. K.; Ng, J.; Smith, C.; Haage, A.; Jadavji, N. M.

10.1101/2024.07.31.606033 — scientific communication and education — Posted on 2024-08-02

4690 Single-cell differential expression analysis between conditions within nested settings

Hafner, L.; Sturm, G.; List, M.

10.1101/2024.08.01.606200 — bioinformatics — Posted on 2024-08-02

4691 CoMPHI: A Novel Composite Machine Learning Approach Utilizing Multiple FeatureRepresentation to Predict Hosts of Bacteriophages

Bodaka, S.; Malgonde, O.

10.1101/2024.07.29.604684 — bioinformatics — Posted on 2024-08-02

4692 WITHDRAWN: Physiological modeling and biomechanical insights of cytokine modulation in COVID-19 and pulmonary fibrosis through a multi-dimensional graph-based approach

Ray, R.; Bhowmik, R.; Shyamal, S. S.; Manaithiya, A.; Gong, W.; Parkkila, S.; Aspatwar, A.

10.1101/2024.05.26.595932 — bioinformatics — Posted on 2024-08-02

4693 Integrin conformation-dependent neutrophil slowing obstructs the capillaries of the pre-metastatic lung in a model of breast cancer

Fercoq, F.; Cairns, G. S.; De Donatis, M.; Mackey, J. B.; Floerchinger, A.; McFarlane, A. J.; Raffo-Iraolagoitia, X. L.; Whyte, D.; Arnott, L. W.; Nixon, C.; Wiesheu, R.; Brown, L.; Al-Khalidi, S.; Norman, J. C.; Roberts, E. W.; Blyth, K.; Coffelt, S. B.; Carlin, L. M.

10.1101/2024.03.19.585724 — immunology — Posted on 2024-08-02

4694 P53 Orchestrates Cancer Metabolism: Unveiling Strategies to Reverse the Warburg Effect

Abukwaik, R.; Vera-Siguenza, E.; Tennant, D.; Spill, F.

10.1101/2024.04.26.591290 — cancer biology — Posted on 2024-08-02

4695 Neutrophils exposed to a cholesterol metabolite secrete extracellular vesicles that promote epithelial-mesenchymal transition and stemness in breast cancer cells.

Krawczynska, N.; Wang, Y.; Lim, K.; Das Gupta, A.; Lenczowski, A.; Abughazaleh, M.; Bendre, S. V.; Kockaya, L. I.; Schane, C. P.; Fei, Y.; Hernandez, A. G.; Drnevich, J.; Chan, J.; Dobrucki, L. W.; Boppart, M. D.; Ostrander, J. H.; Nelson, E. R. R.

10.1101/2024.08.02.606061 — cancer biology — Posted on 2024-08-02

4696 Insights into Therapeutic Discovery Through the Kelch Domain Structure of Keap1 at Ambient Temperature

Yilmaz, M.; Sever, B.; Kutlu, Y.; Gul, M.; Okuducu, C.; Tavli, S.; Otsuka, M.; Fujita, M.; Haliloglu, T.; Ciftci, H.; DeMirci, H.

10.1101/2024.07.30.605796 — biophysics — Posted on 2024-08-02

4697 Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data.

Gabriel, A. A.; Racle, J.; Falquet, M.; Jandus, C.; Gfeller, D.

10.1101/2023.10.11.561826 — bioinformatics — Posted on 2024-08-02

4698 SaprotHub: Making Protein Modeling Accessible to All Biologists

Su, J.; Li, Z.; Han, C.; Zhou, Y.; He, Y.; Shan, J.; Zhou, X.; Chang, X.; Ma, D.; OPMC, T.; Steinegger, M.; Ovchinnikov, S.; Yuan, F.

10.1101/2024.05.24.595648 — bioinformatics — Posted on 2024-08-02

4699 WITHDRAWN: Molecular Insights into Zea mays Active Phytochemicals for Diabetes and Inflammation Treatment: A Web App-Based Machine Learning and Network Pharmacology Approach

Manaithiya, A.; Bhowmik, R.; Elhenawy, A. A.; Sharma, S.; Dinesh, S.; Parkkila, S.; Aspatwar, A.

10.1101/2024.05.05.592582 — bioinformatics — Posted on 2024-08-02

4700 WITHDRAWN: Mechanistic modeling of Mycobacterium tuberculosis β-carbonic anhydrase inhibitors using integrated systems biology and the QSAR approach

Bhowmik, R.; Manaithiya, A.; Parkkinen, J.; Kumar, S.; Mathew, B.; Parikka, M.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.

10.1101/2024.05.07.592909 — bioinformatics — Posted on 2024-08-02

4701 Towards the Genome-scale Discovery of Bivariate Monotonic Classifiers

Fourquet, O.; Krejca, M. S.; Doerr, C.; Schwikowski, B.

10.1101/2023.02.22.529510 — bioinformatics — Posted on 2024-08-02

4702 WITHDRAWN: Elucidating the molecular mechanism of phytochemicals against Parkinson's disease through an integrated systems biology and molecular modeling approach

Bhowmik, R.; Kumar, S.; Manaithiya, A.; Mohan, C. G.; Mathew, B.; Parkkila, S.; Aspatwar, A.

10.1101/2024.05.10.593559 — bioinformatics — Posted on 2024-08-02

4703 WITHDRAWN: Neural Network and Random Forest Algorithms as Catalysts in QSAR/QSAAR Modeling: Targeting β-Carbonic Anhydrase for Antituberculosis Drug Design

Bhowmik, R.; Manaithiya, A.; Ray, R.; Carta, F.; Supuran, C. T.; Parkkila, S.; Aspatwar, A.

10.1101/2024.04.30.591931 — bioinformatics — Posted on 2024-08-02

4704 WITHDRAWN: Physiological modeling into the metaverse of Mycobacterium Tuberculosis Beta CA inhibition mechanism

GiovannuzzI, S.; Shyamal, S. S.; Bhowmik, R.; Ray, R.; Manaithiya, A.; Carta, F.; Parkkila, S.; Aspatwar, A.; Supuran, C. T.

10.1101/2024.05.26.595948 — bioinformatics — Posted on 2024-08-02

4705 Assessment of thermochromic phantoms for characterizing microwave ablation devices

Zia, G.; Lintz, A.; Hardin, C.; Bottiglieri, A.; Sebek, J.; Prakash, P.

10.1101/2024.03.23.584886 — bioengineering — Posted on 2024-08-02

4706 Structural insights into human propionyl-CoA carboxylase (PCC) and 3-methylcrotonyl-CoA carboxylase (MCC)

Zhou, F.; Zhang, Y.; Zhu, Y.; Zhou, Q.; Shi, Y.; Hu, Q.

10.1101/2024.04.30.591959 — biochemistry — Posted on 2024-08-02

4707 Midi-metagenomics: A novel approach for cultivation independent microbial genome reconstruction from environmental samples

Vollmers, J.; Correa Cassal, M.; Kaster, A.-K.

10.1101/2023.01.26.525644 — genomics — Posted on 2024-08-02

4708 Assessing Assembly Errors in Immunoglobulin Loci: A Comprehensive Evaluation of Long-read Genome Assemblies Across Vertebrates

Zhu, Y.; Watson, C. T.; Safonova, Y.; Pennell, M.; Bankevich, A.

10.1101/2024.07.19.604360 — genomics — Posted on 2024-08-02

4709 Age-dependent decline in sperm quality and function in a naturally short-lived vertebrate

Cattelan, S.; Valenzano, D. R.

10.1101/2023.12.13.571459 — evolutionary biology — Posted on 2024-08-02

4710 Positive epistasis for fitness under monosomy: Loss of ribosomal protein stoichiometry reduces the effects of other perturbations

Tutaj, H.; Tomala, K.; Pirog, A.; Marszalek, M.; Korona, R.

10.1101/2023.03.12.532261 — evolutionary biology — Posted on 2024-08-02

4711 Partitioning the Impacts of Spatial-Temporal Variation in Demography and Dispersal on Metapopulation Growth Rates

Schreiber, S.

10.1101/2023.11.01.565238 — ecology — Posted on 2024-08-02

4712 Disentangling the mutational effects on protein stability and interaction of human MLH1

Larsen-Ledet, S.; Stein, A.

10.1101/2024.07.28.605491 — molecular biology — Posted on 2024-08-02

4713 Not only ClpC1 but also ClpX are drug targets of Ilamycins

Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Li, J.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.

10.1101/2024.02.24.581832 — microbiology — Posted on 2024-08-02

4714 Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype

McLean, F.; Omondi, B. R.; Diallo, N.; Otoboh, S.; Kifude, C.; Abdi, A.; Lim, R.; Otto, T.; Ghumra, A.; Rowe, A.

10.1101/2024.07.22.604565 — microbiology — Posted on 2024-08-02

4715 Vangl2 suppresses NF-κB signaling and ameliorates sepsis by targeting p65 for NDP52-mediated autophagic degradation

Lu, J.; Zhang, J.; Jiang, H.; Hu, Z.; Zhang, Y.; He, L.; Yang, J.; Xie, Y.; Wu, D.; Li, H.; Zeng, K.; Tan, P.; Xiao, Q.; Song, Z.; Pan, C.; Bai, X.; Yu, X.

10.1101/2023.03.30.534894 — immunology — Posted on 2024-08-02

4716 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node

Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.

10.1101/2024.07.26.605240 — immunology — Posted on 2024-08-02

4717 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system

Pulvirenti, N.; Righetti, C.; Clemente, F.; Serafini, B.; Pietroboni, A.; Galeota, E.; Rosicarelli, B.; Cordiglieri, C.; Iannone, C.; de Riz, M.; Vasco, C.; Espadas de Arias, A.; De Feo, T.; Valenti, L.; Prati, D.; Abrignani, S.; Gerosa, M.; Caporali, R.; Galimberti, D.; Scarpini, E.; Geginat, J.

10.1101/2024.07.30.605745 — immunology — Posted on 2024-08-02

4718 A taxonomy for human social perception: Data-driven modelling with cinematic stimuli

Santavirta, S.; Malen, T.; Erdemli, A.; Nummenmaa, L.

10.1101/2023.09.28.559888 — neuroscience — Posted on 2024-08-02

4719 Key determinants of the dual clamp/activator function of Complexin

Makke, M.; Pastor-Ruiz, A.; Yarzagaray, A.; Gaya, S.; Zimmer, M.; Frisch, W.; Bruns, D.

10.1101/2023.10.03.560784 — neuroscience — Posted on 2024-08-02

4720 Heterozygous expression of a Kcnt1 gain-of-function variant has differential effects on SST- and PV-expressing cortical GABAergic neurons

Shore, A. N.; Li, K.; Safari, M.; Qunies, A. M.; Spitznagel, B. D.; Weaver, C. D.; Emmitte, K.; Frankel, W.; Weston, M. C.

10.1101/2023.10.11.561953 — neuroscience — Posted on 2024-08-02

4721 DySCo: a general framework for dynamic Functional Connectivity

de Alteriis, G.; Sherwood, O.; Ciaramella, A.; Leech, R.; Cabral, J.; Turkheimer, F. E.; Expert, P.

10.1101/2024.06.12.598743 — neuroscience — Posted on 2024-08-02

4722 Sex-dependent effects of amyloidosis on functional network hub topology is associated with downregulated neuronal gene signatures in the APPswe/PSEN1dE9 double transgenic mouse

Simon, Z. D.; McFarland, K. N.; Golde, T. E.; Chakrabarty, P.; Febo, M.

10.1101/2024.05.13.593982 — neuroscience — Posted on 2024-08-02

4723 The NeuroML ecosystem for standardized multi-scale modeling in neuroscience

Sinha, A.; Gleeson, P.; Marin, B.; Dura-Bernal, S.; Panagiotou, S.; Crook, S.; Cantarelli, M.; Cannon, R. C.; Davison, A. P.; Gurnani, H.; Silver, R. A.

10.1101/2023.12.07.570537 — neuroscience — Posted on 2024-08-02

4724 Impact of aging on the GABAB receptor-mediated connectome

Vasquez, E.; Oresti, G. M.; Paez, M. D.; Callegari, E. A.; Masone, D.; Munoz, E. M.

10.1101/2024.07.31.606013 — neuroscience — Posted on 2024-08-02

4725 HSV-1 infection induces a downstream-shift of the +1 nucleosome

Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.

10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-08-02

4726 Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM

Antenucci, L.; Virtanen, S.; Thapa, C.; Jartti, M.; Pitkänen, I.; Tossavainen, H.; Permi, P.

10.1101/2023.10.13.562287 — biochemistry — Posted on 2024-08-02

4727 Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-08-02

4728 The RND efflux pump EefABC is highly conserved within lineages of E. coli commonly associated with infection.

Pugh, H.; Darby, E.; Burgess, L.; Colclough, A.; Meosa-John, A.-R.; Dunn, S.; Connor, C.; Perry, E.; McNally, A.; Bavro, V.; Blair, J. M. A.

10.1101/2024.08.01.606150 — microbiology — Posted on 2024-08-02

4729 Neuronal selectivity for multiple features in the primary visual cortex

Wei, W.; Merkt, B.; Rotter, S.

10.1101/2022.07.18.500396 — neuroscience — Posted on 2024-08-02

4730 Preliminary attempt to inhibit proliferation of NUT carcinoma cell lines using antisense oligonucleotides targeting NUTM1

Alley, J.; Vincent, B.; Rubinsteyn, A.

10.1101/2024.07.30.605673 — cancer biology — Posted on 2024-08-02

4731 Endocytosis of the plasma membrane carboxylate transporter Jen1 in Saccharomyces cerevisiae under alkali stress: a mechanism for preventing loss of essential metabolites

Barata-Antunes, C.; de Hulster, E.; Cardoso, C.; Ribeiro, I. P.; Fernandes, V.; Leite, B.; Casal, M.; Geros, H.; Pronk, J.; Arino, J.; Mans, R.; Paiva, S.

10.1101/2024.08.01.606176 — microbiology — Posted on 2024-08-02

4732 Prevalence of the Calvin-Benson-Bassham cycle in chemolithoautotrophic psychrophiles and the potential for cold-adapted Rubisco

Harrison, K.; Rapp, J. Z.; Jaffe, A. L.; Deming, J. W.; Young, J.

10.1101/2024.08.01.606197 — microbiology — Posted on 2024-08-02

4733 Complement C3d enables protective immunity capable of distinguishing spontaneously transformed from non-transformed cells

Platt, J. L.; Zhao, C.; Chicca, J.; Pianko, M.; Han, J.; The, S.; Rao, A.; Keller, E.; Barbosa, M. G. d. M.; Naing, L.; Pasieka-Axenov, T.; Axenov, L.; schaefer, S.; Farkash, E.; Cascalho, M.

10.1101/2024.07.31.606044 — immunology — Posted on 2024-08-02

4734 Salidroside Mitigates Malignant Arrhythmias by Restoring Sodium Channel Function During Ultra-Acute Myocardial Infarction

Wang, G.; Zhao, Y.; Zhang, C.; Dong, X.; Sun, S.; Wang, X.; Li, D.; Li, X.; Li, H.; Lu, C.-J.; Du, Y.; Chen, Z.; Lin, F.; Hao, G.

10.1101/2024.07.31.606101 — pharmacology and toxicology — Posted on 2024-08-02

4735 PROSER1 Modulates DNA Demethylation through Dual Mechanisms to Prevent Syndromic Developmental Malformations

Fleming, A.; Knatko, E. V.; Li, X.; Zoch, A.; Heckhausen, Z.; Stransky, S.; Brenes, A. J.; Sidoli, S.; Hajkova, P.; O'Carroll, D.; Rasmussen, K. D.

10.1101/2024.07.31.606086 — developmental biology — Posted on 2024-08-02

4736 Human cell adaptation of the swine acute diarrhea syndrome coronavirus spike protein

Sanjuan, R.; Dufloo, J.; Soriano-Tordera, C.

10.1101/2024.07.29.605615 — microbiology — Posted on 2024-08-02

4737 Enhanced Sampling Simulations of RNA-peptide Binding using Deep Learning Collective Variables

Kumari, N.; Dhull, S.; Karmakar, T.

10.1101/2024.08.01.606277 — biophysics — Posted on 2024-08-02

4738 Toward De Novo Protein Design from Natural Language

Dai, F.; Fan, Y.; Su, J.; Wang, C.; Han, C.; Zhou, X.; Liu, J.; Qian, H.; Wang, S.; Zeng, A.; Wang, Y.; Yuan, F.

10.1101/2024.08.01.606258 — bioengineering — Posted on 2024-08-02

4739 Pollen Partners: The Symbiotic Microbes of Pinus radiata Pollen

Armstrong, C.; Ganasamurthy, S.; Walker, K.; Mercier, C.; Wakelin, S. A.

10.1101/2024.07.31.606094 — ecology — Posted on 2024-08-02

4740 Multiscale Responsive Kinetic Modeling: Quantifying Biomolecular Reaction Flux under Varying Electrochemical Conditions

Weckel-Dahman, H.; Carlsen, R.; Swanson, J. M.

10.1101/2024.08.01.606205 — biophysics — Posted on 2024-08-02

4741 Prediction of Threonine-Tyrosine Kinase Receptor-LigandUnbinding Kinetics with Multiscale Milestoning andMetadynamics

Votapka, L. W.; Ojha, A. A.; Asada, N.; Amaro, R. E.

10.1101/2024.08.01.606239 — biophysics — Posted on 2024-08-02

4742 CRISPR-RNA binding drives structural ordering that primes Cas7-11 for target cleavage

Lin, C. P.; Li, H.; Brogan, D. J.; Wang, T.; Akbari, O. S.; Komives, E. A.

10.1101/2024.08.01.606276 — biophysics — Posted on 2024-08-02

4743 FourierMIL: Fourier filtering-based multiple instance learning for whole slide image analysis

Zheng, Y.; Sharma, H.; Betke, M.; Beane, J.; Kolachalama, V. B.

10.1101/2024.08.01.606256 — bioinformatics — Posted on 2024-08-02

4744 Flux balance analysis and peptide mapping elucidate the impact of bioreactor pH on Chinese Hamster Ovary (CHO) cell metabolism and N-linked glycosylation in the Fab and Fc regions of the produced IgG

Reddy, J. V.; Singh, S. K.; Leibiger, T.; Lee, K. H.; Ierapetritou, M.; Papoutsakis, E. T.

10.1101/2024.08.01.606220 — bioengineering — Posted on 2024-08-02

4745 Chronic contractile activity induced skeletal muscle-derived extracellular vesicles increase mitochondrial biogenesis in recipient myocytes via transmembrane or peripheral membrane proteins

Obi, P. O.; Souza, T. F. G.; Seif, S.; Bydak, B.; Klassen, N.; West, A. R.; Gordon, J. W.; Saleem, A.

10.1101/2024.08.01.605916 — cell biology — Posted on 2024-08-02

4746 The triad interaction of ULK1, ATG13, and FIP200 is required for ULK complex formation and autophagy

Hama, Y.; Fujioka, Y.; Yamamoto, H.; Mizushima, N.; Noda, N. N.

10.1101/2024.08.02.606296 — cell biology — Posted on 2024-08-02

4747 Inhibition of protein or glutamine biosynthesis affect the activation of the light stimulated SBiP1 chaperone by dephosphorylation in Symbiodiniaceae

Castillo-Medina, R. E.; Islas-Flores, T.; Morales-Ruiz, E.; Villanueva, M. A.

10.1101/2024.08.01.606268 — cell biology — Posted on 2024-08-02

4748 MOIRE: A software package for the estimation of allele frequenciesand effective multiplicity of infection from polyallelic data

Murphy, M.; Greenhouse, B.

10.1101/2023.10.03.560769 — genetics — Posted on 2024-08-02

4749 Unveiling reversibility and plasticity in cardiac hypertrophy: insights from a transverse aortic constriction-release model

Shiraishi, M.

10.1101/2024.07.07.602358 — molecular biology — Posted on 2024-08-02

4750 The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy

Collins, K.; Kamath, S.; Meola, T.; Wignall, A.; Joyce, P.

10.1101/2024.07.17.604016 — pharmacology and toxicology — Posted on 2024-08-02

4751 Engineered NKG2C+ NK-like T cells exhibit superior antitumor efficacy while mitigating cytokine release syndrome

Lupo, K. B.; Panjwani, M. K.; Shahid, S.; Sottile, R.; Lawry, C.; Kolk, G.; Kontopolous, T.; Daniyan, A. F.; Chandran, S. S.; Klebanoff, C. A.; Hsu, K. C.

10.1101/2024.07.16.603785 — immunology — Posted on 2024-08-02

4752 The timing of preceding tactile inputs modulates cortical processing

Wan, W.; Ridderinkhof, K. R.; Ghosh, A.

10.1101/2024.07.22.604577 — neuroscience — Posted on 2024-08-02

4753 Beyond the Delay Neural Dynamics: a Decoding Strategy for Working Memory Error Reduction

Ye, Z.; Li, H.; Tian, L.; Zhou, C.

10.1101/2022.06.01.494426 — neuroscience — Posted on 2024-08-02

4754 Feminization of the precarious at the UNAM: examining obstacles to gender equality

ciccia, l.; Espinosa Lugo, G.; Garcia Guzman, G.; Gasca-Pineda, J.; Velez, P.; Espinosa Asuar, L.

10.1101/2024.05.13.593992 — scientific communication and education — Posted on 2024-08-02

4755 Fibroblast Stromal Support Model for Predicting Human Papillomavirus-Associated Cancer Drug Responses.

James, C. D.; Lewis, R. L.; Fakunmoju, A. L.; Witt, A.; Youssef, A. H.; Wang, X.; Rais, N. M.; Tadimari Prabhakar, A.; Machado, J. M.; Otoa, R.; Bristol, M. L.

10.1101/2024.04.09.588680 — cancer biology — Posted on 2024-08-02

4756 Defining Structure-Function Relationships of Amphiphilic Excipients Enables Rational Design of Ultra-Stable Biopharmaceuticals

Prossnitz, A.; Nguyen, L. T.; Eckman, N.; Borkar, S.; Tetef, S.; Auzten, A. A. A.; Fuller, G.; Appel, E.

10.1101/2024.06.17.599313 — bioengineering — Posted on 2024-08-02

4757 Dynamic in vivo mapping of the methylproteome using a chemoenzymatic approach

Farhi, J.; Emenike, B.; Beusch, C. M.; Lee, R. S.; Jones, R. B.; Verma, A. K.; Jones, C. Y.; Foroozani, M.; Reeves, M.; Sad, K.; Parwani, K. K.; Bagchi, P.; Deal, R.; Katz, D. J.; Corbett, A. H.; Gordon, D. E.; Raj, M.; Spangle, J.

10.1101/2022.07.22.501130 — biochemistry — Posted on 2024-08-01

4758 Eco-evolutionary dynamics for finite populations and the noise-induced reversal of selection

Bhat, A. S.; Guttal, V.

10.1101/2024.02.19.580940 — evolutionary biology — Posted on 2024-08-01

4759 Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease

Chen, Y.-C.; Maupas, A.; Nowick, K.

10.1101/2023.12.18.569574 — evolutionary biology — Posted on 2024-08-02

4760 Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-08-01

4761 Protein degradation shapes developmental tempo in mouse and human neural progenitors

Nakanoh, S.; Stamataki, D.; Garcia-Perez, L.; Azzi, C.; Carr, H. L.; Pokhilko, A.; Howell, S.; Yu, L.; Skehel, M.; Oxley, D.; Andrews, S.; Briscoe, J.; Rayon, T.

10.1101/2024.08.01.604391 — developmental biology — Posted on 2024-08-01

4762 Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping.

Foran, G.; Hallam, R. D.; Megaly, M.; Turgambayeva, A.; Antfolk, D.; Li, Y.; Luca, V. C.; Necakov, A.

10.1101/2023.03.17.533124 — cell biology — Posted on 2024-08-01

4763 A Multiplexed SEC-MS Approach to Systematically Study the Interplay Between Protein Assembly-States and Phosphorylation Events

Doron-Mandel, E.; Bokor, B. J.; Ma, Y.; Street, L. A.; Tang, L. C.; Abdou, A. A.; Shah, N. H.; Rosenberger, G.; Jovanovic, M.

10.1101/2023.01.12.523793 — molecular biology — Posted on 2024-08-01

4764 Reproductive Tract Microbial Transitions from Late Gestation to Early Postpartum Using 16S rRNA Metagenetic Profiling in First-Pregnancy Heifers

Druker, S.; Sicsic, R.; Ravid, S.; Scheinin, S.; Raz, T.

10.1101/2024.06.08.598098 — microbiology — Posted on 2024-08-01

4765 Behavioral Imitation with Artificial Neural Networks Leads to Personalized Models of Brain Dynamics During Videogame Play

Kemtur, A.; Paugam, F.; Pinsard, B.; harel, Y.; Sainath, P.; Clei, M. L.; Boyle, J.; jerbi, K.; Bellec, P.

10.1101/2023.10.28.564546 — neuroscience — Posted on 2024-08-01

4766 Assessing the Impact of Selective Attention on the Cortical Tracking of the Speech Envelope in the Delta and Theta Frequency Bands and How Musical Training Does (Not) Affect It

Schuller, A.; Mucke, A.; Riegel, J.; Reichenbach, T.

10.1101/2024.08.01.606154 — neuroscience — Posted on 2024-08-01

4767 Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

Chen, X.; Liu, X.; Hoyos, P. M.; Daniel Hertz, E.; Yao, J.; Zhen, Z.; Gomez, J.

10.1101/2023.11.29.569190 — neuroscience — Posted on 2024-08-01

4768 Dissociable roles of thalamic nuclei in the refinement of reaches to spatial targets

Sibener, L. J.; Mosberger, A. C.; Chen, T. X.; Athalye, V. R.; Murray, J. M.; Costa, R. M.

10.1101/2023.09.20.558560 — neuroscience — Posted on 2024-08-01

4769 "Magnetic Sand" : Illusions of Interactivity

Shimojo, S.; Shimojo, K.; Shimojo, E.; Zheng, S.; Wu, D.-A.

10.1101/2024.07.03.598775 — neuroscience — Posted on 2024-08-01

4770 Direct imaging of neural activity reveals neural circuits via spatiotemporal activation mapping

Keum, J.-Y.; Toi, P. T.; Park, S.; Chun, H.; Park, J.-Y.

10.1101/2024.07.31.606112 — neuroscience — Posted on 2024-08-02

4771 Spatial 3D genome organization controls the activity of bivalent chromatin during human neurogenesis

Ahanger, S. H.; Zhang, C.; Semenza, E. R.; Gil, E.; Cole, M. A.; Wang, L.; Kriegstein, A. R.; Lim, D.

10.1101/2024.08.01.606248 — neuroscience — Posted on 2024-08-02

4772 Annexin and calcium-regulated priming of legume root cells for endosymbiotic infection

Guillory, A.; Fournier, J.; Kelner, A.; Hobecker, K.; Auriac, M.-C.; Frances, L.; Delers, A.; Pedinotti, L.; Le Ru, A.; Keller, J.; Delaux, P.-M.; Gutjahr, C.; Frei Dit Frey, N.; de Carvalho-Niebel, F.

10.1101/2024.01.10.574854 — plant biology — Posted on 2024-08-01

4773 Unveiling Wolbachia pipientis transcriptomic signature in Aedes aegypti: a comprehensive meta-analysis

Mejias, S.; Jimenez, N. E.; Conca, C.; Salgado, J. C.; Gerdtzen, Z. P.

10.1101/2023.09.03.556149 — bioinformatics — Posted on 2024-08-01

4774 Disordered proteins interact with the chemical environment to tune their protective function during drying

KC, S.; Nguyen, K. H.; Nicholson, V.; Walgren, A.; Trent, T.; Gollub, E.; Ramero, S.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.

10.1101/2024.02.28.582506 — biochemistry — Posted on 2024-08-01

4775 Information, certainty, and learning.

Harris, J. A.; Gallistel, C. R.

10.1101/2024.07.31.606111 — animal behavior and cognition — Posted on 2024-08-01

4776 An eye-tracking study of visual attention in chimpanzees and bonobos when viewing different tool-using techniques

Piao, Y.; Brooks, J.; Yamamoto, S.

10.1101/2024.08.01.605994 — animal behavior and cognition — Posted on 2024-08-01

4777 Multiple Protein Structure Alignment at Scale with FoldMason

Gilchrist, C. L. M.; Mirdita, M.; Steinegger, M.

10.1101/2024.08.01.606130 — bioinformatics — Posted on 2024-08-01

4778 The conserved biochemical activity and function of an early metazoan phosphatidylinositol 5 phosphate 4-kinase regulates growth and development.

Krishnan, H.; Muzaffar, S.; Sharma, S.; Ramya, V.; Ghosh, A.; Sowdhamini, R.; PADINJAT, R.

10.1101/2024.08.01.606031 — biochemistry — Posted on 2024-08-01

4779 Characterizing the dual regulation of Neisseria gonorrhoeae tdfJ in response to zinc and iron

Padmanabhan, S.; Stoudenmire, J. L.; Branch, A. H.; Cornelissen, C. N.

10.1101/2024.08.01.606247 — molecular biology — Posted on 2024-08-01

4780 The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts

Pereira, H.; Hoffman, J. I.; Kruger, O.; Czirjak, G. A.; Rinaud, T.; Ottensmann, M.; Gladow, K.-P.; Caspers, B. A.; Maraci, O.; Kaiser, S.; Chakarov, N.

10.1101/2024.08.01.605092 — microbiology — Posted on 2024-08-01

4781 Morphology-dependent entry kinetics and spread of influenza A virus

Peterl, S.; Lahr, C. M.; Schneider, C. N.; Meyer, J.; Podlipensky, X.; Lechner, V.; Villiou, M.; Eis, L.; Klein, S.; Funaya, C.; Cavalcanti-Adam, E. A.; Graw, F.; Selhuber-Unkel, C.; Rohr, K.; Chlanda, P.

10.1101/2024.08.01.605992 — microbiology — Posted on 2024-08-01

4782 Cellular N-myristoyl transferases Are Required for Mammarenavirus Multiplication

Witwit, H.; Betancourt, C.; Cubitt, B.; Khafaji, R.; Kowalski, H.; Jackson, N.; Ye, C.; Martinez-Sobrido, L.; de la Torre, J. C.

10.1101/2024.08.01.606235 — microbiology — Posted on 2024-08-01

4783 Diet outperforms microbial transplant to drive microbiome recovery post-antibiotics

Kennedy, M. S.; Freiburger, A.; Cooper, M.; Beilsmith, K.; St. George, M. L.; Kalski, M.; Cham, C.; Guzzetta, A.; Ng, S. C.; Chan, F. K.; Rubin, D.; Henry, C. S.; Bergelson, J.; Chang, E. B.

10.1101/2024.08.01.606245 — microbiology — Posted on 2024-08-01

4784 Establishment of a rapid method to assemble and transfer DNA fragments into the JCVI-syn3B minimal synthetic bacterial genome

Uenoyama, A.; Kiyama, H.; Mimura, M.; Miyata, M.

10.1101/2024.08.01.606163 — synthetic biology — Posted on 2024-08-01

4785 Cyclin A/B RxL Macrocyclic Inhibitors to Treat Cancers with High E2F Activity

Singh, S.; Gleason, C. E.; Fang, M.; Laimon, Y. N.; Khivansara, V.; Xie, S.; Durmaz, Y. T.; Sarkar, A.; Ngo, K.; Savla, V.; Li, Y.; Abu-Remaileh, M.; Li, X.; Tuladhar, B.; Odeh, R.; Hamkins-Indik, F.; He, D.; Membreno, M. W.; Nosrati, M.; Gushwa, N. N.; Leung, S. S. F.; Fraga-Walton, B.; Hernandez, L.; Baldomero, M. P.; Lent, B. M.; Spellmeyer, D.; Luna, J. F.; Hoang, D.; Gritsenko, Y.; Chand, M.; DeMart, M. K.; Metobo, S.; Bhatt, C.; Shapiro, J. A.; Yang, K.; Dupper, N. J.; Bockus, A. T.; Doench, J. G.; Aggen, J. B.; Liu, L.-F.; Levin, B.; Wang, E. W.; Vendrell, I.; Fischer, R.; Kessler, B. M

10.1101/2024.08.01.605889 — cancer biology — Posted on 2024-08-01

4786 Deep Learning Reaction Network: a machine learning framework for modeling time resolved data

Alagna, N.; Duzs, B.; Koeppl, H.; Walther, A.; Gerber, S.

10.1101/2024.07.31.606055 — biophysics — Posted on 2024-08-01

4787 Vanadium-dependent haloperoxidases from diverse microbes halogenate exogenous alkyl quinolone quorum sensing signals

Baumgartner, J. T.; McCaughey, C. S.; Fleming, H. S.; Lentz, A. R.; Sanchez, L. M.; McKinnie, S. M. K.

10.1101/2024.07.31.606109 — biochemistry — Posted on 2024-08-01

4788 SMURF1/2 are novel regulators of WNK1 stability

Jaykumar, A. B.; Plumber, S.; Binns, D.; Wichaidit, C.; Luby-Phelps, K.; Cobb, M. H.

10.1101/2024.07.31.606092 — biochemistry — Posted on 2024-08-01

4789 High-Efficiency Capture and Proteomic Analysis of Plasma-Derived Extracellular Vesicles through Affinity Purification

Zhang, G.-Y.; Ma, C.-x.; Ma, L.; Wei, D.; Wu, Y.-N.; Li, Y.; Xu, Z.-H.; Liu, Y.-F.; Cai, Y.-H.; Yu, E. Y.-W.; Zhu, Y.-F.; Zhang, H.

10.1101/2024.08.01.605729 — biochemistry — Posted on 2024-08-01

4790 Activation and regulation of a p38α MAPK by its downstream MAPKAP kinase through feedback phosphorylation and LLPS-driven condensate formation.

Ray, P.; Rao, P. T.; Nandi, M.; Haque, A.; Mitra, S.; Raychaudhuri, S.; Ghosh-Roy, A.; Polley, S.

10.1101/2024.08.01.606155 — biochemistry — Posted on 2024-08-01

4791 Development of the novel amylin receptor activators with nanomolar potency by peptide mutagenesis

Lee, S.

10.1101/2024.07.31.606116 — biochemistry — Posted on 2024-08-01

4792 EPInformer: A Scalable Deep Learning Framework for Gene Expression Prediction by Integrating Promoter-enhancer Sequences with Multimodal Epigenomic Data

Lin, J.; Luo, R.; Pinello, L.

10.1101/2024.08.01.606099 — genomics — Posted on 2024-08-01

4793 Cardiac p16 Expression Following Vape Exposure with Nicotine Shows Sex-Specific Induction in Males but not Females

Shain, A.; Savko, C.; Rokaw, S.; Jaafar, F.; Rieder, A.; Wright, M. K.; Phillips, J. A.; Konja, N.; Michael, S.; Mathews, H.; Jerjees, G.; Bailey, B.; Sussman, M.

10.1101/2024.08.01.606074 — molecular biology — Posted on 2024-08-01

4794 Structure-based mechanism of RyR channel operation by calcium and magnesium ions

Zahradnikova, A.; Pavelkova, J.; Sabo, M.; Baday, S.; Zahradnik, I.

10.1101/2024.08.01.606133 — molecular biology — Posted on 2024-08-01

4795 PDS5s control the Arabidopsis 3D genome by suppressing the formation of TAD-like domains

Goebel, A. M.; Zhou, S.; Wang, Z.; Tzourtzou, S.; Himmelbach, A.; Zheng, S.; Pradillo, M.; Liu, C.; JIANG, H.

10.1101/2024.07.31.606105 — molecular biology — Posted on 2024-08-01

4796 MinD2 modulates cell shape and motility in the archaeon Haloferax volcanii

Patro, M.; Sivabalasarma, S.; Gfrerer, S.; Rodriguez, M.; Nussbaum, P.; Ithurbide, S.; Albers, S.-V.

10.1101/2024.08.01.606218 — microbiology — Posted on 2024-08-01

4797 Plasmids encode and can mobilize onion pathogenicity in Pantoea agglomerans

Shin, G. Y.; Asselin, J. A.; Smith, A.; Aegerter, B.; Coutinho, T.; Zhao, M.; Dutta, B.; Mazzone, J.; Neupane, R.; Gugino, B.; Hoepting, C.; Khanal, M.; Malla, S.; Nischwitz, C.; Sidhu, J.; Burke, A. M.; Davey, J.; Uchanski, M.; Derie, M. L.; du Toit, L. J.; Stresow, S.; Bonasera, J. M.; Stodghill, P.; Kvitko, B. H.

10.1101/2024.08.01.606178 — microbiology — Posted on 2024-08-01

4798 MinD proteins regulate CetZ1 localisation in Haloferax volcanii

Brown, H. J.; Duggin, I. G.

10.1101/2024.08.01.606189 — microbiology — Posted on 2024-08-01

4799 Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides

Fu, Y.; Luo, X.-D.; Li, J.-Z.; Mo, Q.-Y.; Wang, X.; Zhao, Y.; Zhang, Y.-M.; Luo, H.-T.; Xia, D.-Y.; Ma, W.-Q.; Chen, J.-Y.; Wang, L.-H.; Deng, Q.-Y.; Ben, L.; Kashif Saleemi, M.; Jiang, X.-Z.; Chen, J.; Miao, K.; Lin, Z.-P.; Zhang, P.; Ye, H.; Cao, Q.-Y.; Zhu, Y.-W.; Yang, L.; Tu, Q.; Wang, W.

10.1101/2024.08.01.606206 — microbiology — Posted on 2024-08-01

4800 Visualizing Liquid Distribution Across Hyphal Networks with Cellular Resolution

Clark, A. J.; Masters-Clark, E.; Moratto, E.; Junier, P.; Stanley, C. E.

10.1101/2024.08.01.606151 — microbiology — Posted on 2024-08-01

4801 Valorisation of spent cultivated meat media for recombinant FGF2 production in GRAS Lactococcus lactis

Rizal, J.; Mainali, P.; Quek, J. P.; Tan, L. L.; Bi, J.; Chan, A. J.; Gaffoor, A. A.; Chew, L. J. M.; Sugii, S.; Ng, S. K.; Ow, D. S.-W.; Wong, F. T.

10.1101/2024.08.01.606190 — microbiology — Posted on 2024-08-01

4802 ARPE-19 Epithelial Cells Fail To Initiate Type-I Interferon Signaling in Response to Human Cytomegalovirus Infection.

Andrade-Medina, M.; Greco, T. M.; Ileana M Cristea, I. M.; Oberstein, A.

10.1101/2024.08.01.606090 — microbiology — Posted on 2024-08-01

4803 The RND efflux pump EefABC is highly conserved within lineages of E. coli commonly associated with infection.

Pugh, H.; Darby, E.; Burgess, L.; Colclough, A.; Meosa-John, A.-R.; Dunn, S.; Connor, C.; Perry, E.; McNally, A.; Bavro, V.; Blair, J. M. A.

10.1101/2024.08.01.606150 — microbiology — Posted on 2024-08-01

4804 moPPIt: De Novo Generation of Motif-Specific Binders with Protein Language Models

Chen, T.; Zhang, Y.; Chatterjee, P.

10.1101/2024.07.31.606098 — synthetic biology — Posted on 2024-08-01

4805 Towards an eco-epidemiological framework for managing freshwater crayfish communities confronted with crayfish plague

Bozzuto, C.; Schmidt-Posthaus, H.; Adrian-Kalchhauser, I.; Pisano, S. R. R.

10.1101/2024.07.31.606058 — ecology — Posted on 2024-08-01

4806 IL-27 Stablizes Myc-Mediated Transcription In Memory-Fated, Vaccine-Elicited CD8+ T Cells

Kedl, R. M.; Thompson, S. B.; Harbell, M.; Manalastas, J.; Ivanova, D. L.; Riemondy, K. A.; Lasda, E.; Chen, V.; Hesselberth, J. R.; Phan, A. T. A.; Christian, D. A.; Hunter, C.; Brunetti, T.; Klarquist, J.; Gapin, L.

10.1101/2024.07.31.606026 — immunology — Posted on 2024-08-01

4807 Synergistic combination therapy with ONC201 or ONC206, Enzalutamide and Darolutamide in preclinical studies of castration-resistant prostate cancer

Wu, L. J.; Pinho-Schwermann, M.; Zhou, L.; Zhang, L.; Huntington, K. E.; Malpass, R.; Seyhan, A. A.; Carneiro, B. A.; El-Deiry, W. S.

10.1101/2024.07.31.606054 — cancer biology — Posted on 2024-08-01

4808 Contact-based thymidylate transfer promotes collective tumor growth

Siddiqui, M. A.; Roemer, A. M. A.; Pinna, L.; Ramesh, V.; Moeller, S. S.; Gollavilli, P. N.; Turtos, A. M.; Varghese, S.; Guldborg, L. B.; Palani, N. P.; Napoli, F.; Volante, M.; Swietach, P.; Ceppi, P.

10.1101/2024.07.31.606056 — cancer biology — Posted on 2024-08-01

4809 Deciphering octoploid strawberry evolution with serial LTR similarity matrices for subgenome partition

Lyu, H.; Ou, S.; Yim, W. C.; Yu, Q.

10.1101/2024.07.31.606053 — bioinformatics — Posted on 2024-08-01

4810 Leveraging microtopography to pattern multi-oriented muscle actuators

Rossy, T.; Schwendeman, L.; Bawa, M.; Umashankar, P.; Raman, R.

10.1101/2024.07.31.606059 — bioengineering — Posted on 2024-08-01

4811 Neutralizing antibodies elicited in sequentially immunized macaques recognize V3 residues on altered conformations of HIV-1 Env trimer

DeLaitsch, A. T.; Keeffe, J. R.; Gristick, H. B.; Lee, J. A.; Ding, W.; Liu, W.; Skelly, A. N.; Shaw, G. M.; Hahn, B. H.; Bjorkman, P. J.

10.1101/2024.07.31.605918 — immunology — Posted on 2024-08-01

4812 What the Average Really Means: Dissociating Effect Size and Effect Prevalence using p-curve Mixtures

Veillette, J. P.; Nusbaum, H. C.

10.1101/2024.07.31.606048 — neuroscience — Posted on 2024-08-01

4813 Iowa Brain-Behavior Modeling Toolkit: An Open-Source MATLAB Tool for Inferential and Predictive Modeling of Imaging-Behavior and Lesion-Deficit Relationships

Griffis, J. C.; Bruss, J.; Acker, S. F.; Shea, C.; Tranel, D.; Boes, A. D.

10.1101/2024.07.31.606046 — neuroscience — Posted on 2024-08-01

4814 Widespread male sterility and trioecy in androdioecious Mercurialis annua: an account of its distribution, its genetic basis, and estimates of its morph-specific fitness components

Nguyen, M. T.; Martignier, T.; Pannell, J. R.

10.1101/2024.07.31.605989 — plant biology — Posted on 2024-08-01

4815 Evaluating the Importance of Glucagon in the Insulin-Glucose Regulatory System: A Mechanistic Modeling Approach

Dalton, M.; Asante-Asamani, E.; Greene, J.

10.1101/2024.07.31.606029 — systems biology — Posted on 2024-08-01

4816 Autophagy-mediated CTR1 turnover orchestrates the reciprocal interaction between autophagy and ethylene signaling

Park, H. L.; Zhang, W.; Chien, Y.-c.; Park, C.; Yoon, G.

10.1101/2024.07.31.606019 — plant biology — Posted on 2024-08-01

4817 MDR1 DNA glycosylase regulates the expression of genomically imprinted genes and helitrons

Higgins, K. M.; Gent, J. I.; Anderson, S. N.

10.1101/2024.07.31.606038 — plant biology — Posted on 2024-08-01

4818 Sustained Strain Applied at High Rates Drives Dynamic Tensioning in Epithelial Cells

Safa, B. T.; Rosenbohm, J.; Esfahani, A. M.; Minnick, G.; Moghaddam, A. O.; Lavrik, N. V.; Huang, C.; Charras, G.; Kabla, A.; Yang, R.

10.1101/2024.07.31.606021 — biophysics — Posted on 2024-08-01

4819 Long axial-range double-helix point spread functions for 3D volumetric super-resolution imaging

Nakatani, Y.; Gaumer, S.; Shechtman, Y.; Gustavsson, A.-K.

10.1101/2024.07.31.605907 — biophysics — Posted on 2024-08-01

4820 A novel hybrid Wireless Integrated Sensing Detector for simultaneous EEG and MRI (WISDEM)

Chen, Y.; Qian, W.; Razansky, D.; Yu, X.; Qian, C.

10.1101/2024.07.31.606016 — bioengineering — Posted on 2024-08-01

4821 Interferon-induced activation state of circulating dendritic cells and monocytes triggered by yellow fever vaccination correlates with early protective antibody responses

Winheim, E.; Santos-Peral, A.; Ehm, T.; Rinke, L.; Riemer, S.; Zaucha, M.; Goresch, S.; Lehmann, L.; Eisenaecher, K.; Pritsch, M.; Spaeth, G. B.; Straub, T.; Rothenfusser, S.; Krug, A. B.

10.1101/2024.07.31.606034 — immunology — Posted on 2024-08-01

4822 Experience instructs the refinement of feature-selectivity in the mouse primary visual thalamus

Sonoda, T.; Stephany, C.-E.; Kelley, K.; Kang, D.; Wu, R.; Uzgare, M. R.; Fagiolini, M.; Greenberg, M. E.; Chen, C.

10.1101/2024.07.31.605460 — neuroscience — Posted on 2024-08-01

4823 Single-cell spatial transcriptomics reveals molecular patterns of selective neuronal vulnerability to α-synuclein pathology in a transgenic mouse model of Lewy body disease

Horan-Portelance, L.; Iba, M.; Acri, D. J.; Gibbs, J. R.; Masliah, E.; Cookson, M. R.

10.1101/2024.07.31.606032 — neuroscience — Posted on 2024-08-01

4824 Social Isolation During Adolescence Differentially Affects Spatial Learning in Adult Male and Female Mice

Hanif, S.; Sclar, M.; Lee, J.; Nichols, C.; Likhtik, E.; Burghardt, N. S.

10.1101/2024.07.31.606027 — neuroscience — Posted on 2024-08-01

4825 Sphingosine-1-phosphate receptor 3 activation promotes sociability and regulates the expression of genes associated with anxiolytic-like behavior

Castro-Vildosola, J.; Bryan, C.-A.; Tajamal, N.; Jonnalagadda, S. A.; Kasturi, A.; Tilly, J.; Garcia, I.; Kumar, R.; Fried, N. T.; Hala, T.; Corbett, B. F.

10.1101/2024.07.31.606030 — neuroscience — Posted on 2024-08-01

4826 Characterization of Social and Repetitive Behaviors of Mllt11/Af1q/TcF7c Conditional Knockout Mice

Witt, E. A.; Stanton-Turcotte, D.; Garay, P.; Ge, J.; Iulianella, A.

10.1101/2024.07.31.606037 — neuroscience — Posted on 2024-08-01

4827 Comparative lifespan and healthspan of nonhuman primate species common to biomedical research

10.1101/2024.07.31.606010 — physiology — Posted on 2024-08-01

4828 IDENTIFICATION OF IMMUNE RESPONSE AND RNA NETWORK OF RHEUMATOID ARTHRITIS AND MOLECULAR DOCKING OF CELASTRUS PANICULATUS AS POTENTIAL THERAPEUTIC AGENT

SWAMINATHAN, V.

10.1101/2024.07.30.605947 — bioinformatics — Posted on 2024-08-01

4829 Center of Mass Work Components May Offer Estimates for Preferred Walking Speeds for Any Walking Conditions

Hosseini-Yazdi, S.-S.

10.1101/2024.07.16.603701 — bioengineering — Posted on 2024-08-01

4830 The Significance of Uneven Walking Transitory Modulations in Walking Momentum Regulation and Active Work

Hosseini-Yazdi, S.-S.

10.1101/2024.07.16.603711 — bioengineering — Posted on 2024-08-01

4831 The Powered Simplest Walking Model Explains the Different Vertical Ground Reaction Force Amplitudes at Elevated Walking Speeds

Hosseini-Yazdi, S.-S.

10.1101/2024.07.16.603707 — bioengineering — Posted on 2024-08-01

4832 The Energetics of Maintaining the Lateral Balance Are Terrain-Specific; a Normal Lookahead Significantly Reduces Active Balance Maintenance Work

Hosseini-Yazdi, S.-S.

10.1101/2024.07.16.603705 — bioengineering — Posted on 2024-08-01

4833 Preparation of inexpensive, pre-stained molecular weight marker using proteins isolated from chicken egg for SDS PAGE and Western blot application

Balaji, K. K.; Jain, V. V.; Rangasamy, S. S.; Rajendran, G. G.; Kittappa, V. V.; Muruganandam, A. A.

10.1101/2024.07.30.604739 — molecular biology — Posted on 2024-08-01

4834 Infiltrating lipid-rich macrophage subpopulations identified as a regulator of increasing prostate size in human benign prostatic hyperplasia

Lanman, N. A.; Meco, E.; Fitchev, P.; Kolliegbo, A. K.; Broman, M. M.; Filipovich, Y.; Kothandaraman, H.; Cresswell, G. M.; Talaty, P.; Antoniak, M.; Brumer, S.; Glaser, A. P.; Higgins, A. M.; Helfand, B. T.; Franco, O. E.; Crawford, S. E.; Ratliff, T. L.; Hayward, S. W.; Vickman, R. E.

10.1101/2024.06.07.597992 — immunology — Posted on 2024-08-01

4835 Rapid liquid biopsy assessment through gene profiling from the kidney biopsy transport medium: a technical validation and a proof-of-concept pilot study

Li, Z.; Welters, M. J. P.; de Vries, A. P. J.; Bruijn, J. A.; Baelde, H. J.; Kers, J.

10.1101/2024.07.28.604919 — pathology — Posted on 2024-08-01

4836 Experimental evolution of evolvability

Barnett, M.; Zeller, L.; Rainey, P. B.

10.1101/2024.05.01.592015 — evolutionary biology — Posted on 2024-08-01

4837 Causal inference with observational data and unobserved confounding variables

Byrnes, J. E. K.; Dee, L. E.

10.1101/2024.02.26.582072 — ecology — Posted on 2024-08-01

4838 Extensive mutual influences of SMC complexes shape 3D genome folding

Zhang, H.; Zhao, H.; Shu, L.; Liu, F.; Lin, E.; Xia, S.; Wang, B.; Wang, M.; Shan, F.; Lin, Y.; Zhang, L.; Gu, Y.; Blobel, G.

10.1101/2024.07.31.606012 — cell biology — Posted on 2024-08-01

4839 Bacteria face trade-offs in the decomposition of complex biopolymers

Guseva, K.; Mohrlok, M.; Alteio, L.; Schmidt, H.; Pollak, S.; Kaiser, C.

10.1101/2023.10.03.560709 — microbiology — Posted on 2024-08-01

4840 Differential encoding of fear learning and fear expression in the ventral and dorsal hippocampus

Pompili, M. N.; Hamou, N.; Wiener, S. I.

10.1101/2024.01.26.577384 — neuroscience — Posted on 2024-08-01

4841 Thalamic nuclei in patients with chronic facial pain: gray matter volume patterns before and after surgery

Pashkov, A.; Filimonova, E.; Zaitsev, B.; Martirosyan, A.; Moisak, G.; Rzaev, J.

10.1101/2023.12.20.572277 — neuroscience — Posted on 2024-08-01

4842 REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness

Mortazavi, N.; Talwar, P.; Koshmanova, E.; Sharifpour, R.; Beckers, E.; Berger, A.; Campbell, I.; Paparella, I.; Balda, F.; Dardour Hamzaoui, I.; Berthomier, C.; Bastin, C.; Phillips, C.; Maquet, P.; Collette, F.; Zubkov, M.; Lamalle, L.; Vandewalle, G.

10.1101/2024.07.12.603275 — neuroscience — Posted on 2024-08-01

4843 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice

10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-08-01

4844 Decoding in the fourth dimension: Classification of temporal patterns and their generalization across locations

Santos-Mayo, A.; Gilbert, F.; Ahumada, L.; Traiser, C.; Engle, H.; Panitz, C.; Ding, M.; Keil, A.

10.1101/2024.06.19.599699 — neuroscience — Posted on 2024-08-01

4845 Combining systems and synthetic biology for in vivo enzymology

Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.

10.1101/2024.02.02.578620 — systems biology — Posted on 2024-08-01

4846 Autophagy at Crossroads: Modulating Responses to Combined Heat Stress and Bacterial Infection

Seybold, H.; Katz, E.; Soroka, Y.; Avin-Wittenberg, T.

10.1101/2024.03.22.586360 — plant biology — Posted on 2024-08-01

4847 Analysis of multi-condition single-cell data with latent embedding multivariate regression

Ahlmann-Eltze, C.; Huber, W.

10.1101/2023.03.06.531268 — bioinformatics — Posted on 2024-08-01

4848 Expanding the space of self-reproducing RNAs using probabilistic generative models

Lambert, C. N.; Opuu, V.; Calvanese, F.; Zamponi, F.; Hayden, E. J.; Weigt, M.; Smerlak, M.; Nghe, P.

10.1101/2024.07.31.605758 — biochemistry — Posted on 2024-08-01

4849 Amyloids at the border: deep mutagenesis and random sequence extension reveal an incomplete amyloid-forming motif in Bri2 that turns amyloidogenic upon C-terminal extension

Martin, M.; Bolognesi, B.

10.1101/2023.09.15.557952 — genomics — Posted on 2024-08-01

4850 G-quadruplex formation in GCK and TM6SF2 are targets for differential DNA methylation in metabolic disease and hepatocellular carcinoma patients

Lahnsteiner, A.; Ellmer, V.; Oberlercher, A.; Liutkeviciute, Z.; Schoenauer, E.; Paulweber, B.; Aigner, E.; Risch, A.

10.1101/2024.03.21.585382 — genetics — Posted on 2024-08-01

4851 A genetic toolbox for the turquoise killifish identifies sporadic age-related cancer

Rozenberg, I.; Franek, R.; Moses, E.; Atlan, T.; Diehl, M.; Oron-Gottesman, A.; Bergman, M.; Astre, G.; Rosental, B.; Chrzanowski, H.; Harel, I.

10.1101/2023.05.01.538839 — genetics — Posted on 2024-08-01

4852 Evolution of divergent daily temporal niches shaped by male-male competition can generate sympatric speciation

Bouinier, T.; Brunaud, A.; Smadi, C.; Llaurens, V.

10.1101/2024.07.31.601896 — evolutionary biology — Posted on 2024-08-01

4853 Single-molecule tracking reveals the dynamics of Ipl1 recruitment to the kinetochores and spindles in S. cerevisiae

Podh, N. K.; Das, A.; Kumari, A.; Garg, K.; Yadav, R.; Kashyap, K.; Islam, S.; Gupta, A.; Mehta, G.

10.1101/2024.08.01.606162 — cell biology — Posted on 2024-08-01

4854 Src promotes tumor cell invasion by hijacking the translation machinery

BONNARD, B.; Chatefau, A.; Dourthe, C.; Di Tommaso, S.; Dupuy, J.-W.; Mahouche, I.; Solorzano, J.; Le Bras, M.; Raymond, A.-A.; Moreau, V.; Jabouille, A.; Blangy, A.; Saltel, F.

10.1101/2024.08.01.606119 — cell biology — Posted on 2024-08-01

4855 Silk-Ovarioids: Establishment and characterization of human ovarian primary cells 3D-model system

Di Nisio, V.; Li, T.; Xiao, Z.; Papaikonomou, K.; Damdimopoulos, A.; Vegvari, A.; Lebre, F.; Alfaro-Moreno, E.; Pedersen, M.; Svingen, T.; Zubarev, R.; Acharya, G.; Damdimopoulou, P.; Salumets, A.

10.1101/2024.07.31.606024 — cell biology — Posted on 2024-08-01

4856 The impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespan

Cefis, M.; Marcangeli, V.; Hammad, R.; Granet, J.; Leduc-Gaudet, J.-P.; Gaudreau, P.; Trumpff, C.; Huang, Q.; Picard, M.; Aubertin-Leheudre, M.; Belanger, M.; Morais, J. A.; Gouspillou, G.

10.1101/2024.07.09.602758 — cell biology — Posted on 2024-08-01

4857 A Genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma

Menchon, G.; Gaci, A.; Matvere, A.; Aubry, M.; Bore, A.; Goyenvalle, A.; Pedeux, R.

10.1101/2024.03.29.587208 — molecular biology — Posted on 2024-08-01

4858 DeepOrientation: Deep Orientation Estimation of Macromolecules in Cryo-electron tomography

Hajarolasvadi, N.; Phelippeau, H.; Martinez-Sanchez, A.; Brandt, R.; Suau, P.-N.; Baum, D.

10.1101/2024.07.12.603241 — molecular biology — Posted on 2024-08-01

4859 MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

Graca, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.

10.1101/2024.03.26.586840 — microbiology — Posted on 2024-08-01

4860 Impact of aging on the GABAB receptor-mediated connectome

Vasquez, E.; Oresti, G. M.; Paez, M. D.; Callegari, E. A.; Masone, D. F.; Munoz, E. M.

10.1101/2024.07.31.606013 — neuroscience — Posted on 2024-08-01

4861 Preferential assimilation, metabolism, and transfer of organic nitrogen to host plants by Mucoromycotina 'fine root endophytes'

Howard, N. O. A.; Williams, A.; Durant, E.; Pressel, S.; Daniell, T. J.; Field, K. J.

10.1101/2024.07.31.606011 — plant biology — Posted on 2024-08-01

4862 Recurrent breakpoints in the BRD4 locus reduce toxicity associated with gene amplification

Wala, J.; Dalin, S.; Webster, S.; Shapira, O.; Busanovich, J.; Beroukhim, R.; Bandopadhayay, P.; Rendo, V.

10.1101/2024.07.31.606009 — cancer biology — Posted on 2024-08-01

4863 Obtaining super-resolved images at the mesoscale through Super-Resolution Radial Fluctuations

Brown, M.; Foylan, S.; Rooney, L. M.; Gould, G. W.; McConnell, G.

10.1101/2024.07.31.606008 — biophysics — Posted on 2024-08-01

4864 Extensive admixture among karst-obligate salamandersreveals evidence of recent divergence and gene exchangethrough aquifers

Nice, C. C.; Bell, K. L.; Gompert, Z.; Lucas, L. K.; Ott, J. R.; Tovar, R. U.; Crump, P.; Diaz, P. H.

10.1101/2024.07.31.606001 — evolutionary biology — Posted on 2024-08-01

4865 Laminin 111 triggers cell quiescence and long-term survival by inducing IQGAP1-mediated cytosolic scaffolding of ERK and BAD inactivation

Yu, C.; Malijauskaite, S.; Hinze, C.; Franzoni, M.; Hickey, S.; Marcar, L.; Peak-Chew, S. Y.; Cryar, A.; Bain, C.; Marsden, J.; Allardyce, J. M.; Mendes-Pereira, A. M.; McMahon, H. T.; Thalassinos, K.; McGourty, K.; Boucrot, E.

10.1101/2024.08.01.606017 — cell biology — Posted on 2024-08-01

4866 The neural dynamics of positive and negative expectations of pain

Wittkamp, C. A.; Wolf, M.-I.; Rose, M.

10.1101/2024.03.05.583509 — neuroscience — Posted on 2024-08-01

4867 Aging amplifies sex differences in low alpha and low beta EEG oscillations

Han, C.; Cheung, V. C. K.; Chan, R. H. M.

10.1101/2024.07.31.603949 — neuroscience — Posted on 2024-08-01

4868 Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus

Kirkwood, N. K.; Prosser, H.; Yap, M. W.; Gibson, J.; Cook, R.; Reddin, I.; Stranger, A.; Howes, E.; Zainal, N.; Periyasamy, M.; Conticello, S. G.; Thomas, G. J.; Scott, J.; Bishop, K. N.; Ali, S.; Bradley, A.; Fenton, T. R.

10.1101/2024.07.30.605801 — cancer biology — Posted on 2024-08-01

4869 Metabolic modelling reveals increased autonomy and antagonism in type 2 diabetic gut microbiota

Kadibalban, A. S.; Kunstner, A.; Schroder, T.; Kaleta, C.; Zauleck, J.; Witt, O.; Marinos, G.

10.1101/2024.07.31.605966 — systems biology — Posted on 2024-08-01

4870 JM-20 administration to animals with lesion of the nigrostriatal dopamine pathway induced by 6-hydroxydopamine, partially reverses motor damage and oxidative stress

Fonseca Fonseca, L. A.; Tano Portuondo, L. R.; Ramirez-Sanchez, J.; Pavon Fuentes, N.; Mondelo Rodriguez, A.; Amaral da Silva, V. D.; Lima Costa, S.; Nunez-Figueredo, Y.

10.1101/2024.07.30.605870 — neuroscience — Posted on 2024-08-01

4871 Self-association enhances early attentional selection through automatic prioritization of socially salient signals

Scheller, M.; Tunnermann, J.; Fredriksson, K.; Fang, H.; Sui, J.

10.1101/2024.07.31.605951 — neuroscience — Posted on 2024-08-01

4872 Histone H3 E50K mutation confers oncogenic activity and supports an EMT phenotype

Sad, K.; Jones, C. Y.; Fawwal, D. V.; Hill, E. J.; Skinner, K.; Lustenberger, S.; Lee, R. S.; Elayavalli, S. R.; Farhi, J.; Lemon, L. D.; Fasken, M. B.; Hong, A. L.; Sloan, S. A.; Corbett, A. H.; Spangle, J. M.

10.1101/2023.10.11.561775 — cancer biology — Posted on 2024-08-01

4873 Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-08-01

4874 Genome-Wide Profiling of Soybean WRINKLED1 Transcription Factor Binding Sites Provides Insight into Seed Storage Lipid Biosynthesis

Jo, L.; Pelletier, J.; Goldberg, R. B.; Harada, J. J.

10.1101/2024.01.23.576967 — plant biology — Posted on 2024-08-01

4875 Modeling corticotroph deficiency with pituitary organoids supports the functional role of NFKB2 in human pituitary differentiation

Mac, T. T.; Fauquier, T.; Jullien, N.; Romanet, P.; Etchevers, H. C.; Barlier, A.; Castinetti, F.; Brue, T.

10.1101/2023.08.03.551772 — developmental biology — Posted on 2024-08-01

4876 Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

Dong, P.; Li, Y.; Wang, Y.; Zhao, Q.; Lu, T.; Guo, T.; Ma, J.; Yang, B.; Wu, H.; Huang, H.

10.1101/2024.07.03.601877 — developmental biology — Posted on 2024-08-01

4877 The effect of dietary fish oil replacement by microalgae on the gilthead sea bream midgut bacterial microbiota

Katsoulis-Dimitriou, S.; Nikouli, E.; Gkalogianni, E.-Z.; Karapanagiotidis, I.; Kormas, K.

10.1101/2024.01.24.576938 — microbiology — Posted on 2024-08-01

4878 Predictive reward-prediction errors of climbing fiber inputs integrate modular reinforcement learning with supervised learning

Hoang, H.; Tsutsumi, S.; Matsuzaki, M.; Kano, M.; Toyama, K.; Kitamura, K.; Kawato, M.

10.1101/2023.03.13.532374 — neuroscience — Posted on 2024-08-01

4879 Hippocampal-prefrontal communication subspaces align with behavioral and network patterns in a spatial memory task

Young, R. A.; Shin, J. D.; Guo, Z.; Jadhav, S. P.

10.1101/2024.07.08.601617 — neuroscience — Posted on 2024-08-01

4880 Role of desmoplakin in supporting neuronal activity, neurogenic processes, and emotional-related behaviors in the dentate gyrus

Otsubo, K.; Sakashita, N.; Nishimoto, Y.; Sato, Y.; Tsutsui, T.; Kobayashi, K.; Suzuki, K.; Segi-Nishida, E.

10.1101/2023.11.17.567646 — neuroscience — Posted on 2024-08-01

4881 Reward history cues focal attention in whisker somatosensory cortex

Ramamurthy, D. L.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.

10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-08-01

Archive, 2024-08