bioRxiv directory

Tu, J. C.; Wang, Y.; Wang, X.; Dierker, D.; Sobolewski, C. M.; Day, T. K. M.; Kardan, O.; Miranda Dominguez, O.; Moore, L. A.; Elison, J. T.; Gordon, E. M.; Laumann, T. O.; Eggebrecht, A. T.; Wheelock, M. D.

10.1101/2024.07.31.606025 — neuroscience — Posted on 2024-07-31

4 A distinct circuit for biasing visual perceptual decisions and modulating superior colliculus activity through the mouse posterior striatum

Cover, K. K.; Elliott, K.; Preuss, S. M.; Krauzlis, R. J.

10.1101/2024.07.31.605853 — neuroscience — Posted on 2024-07-31

5 Motor sequence learning-induced corticospinal plasticity is biased towards sensorimotor mu rhythm peak phases

Suresh, T.; Iwane, F.; Zhang, M.; McElmurry, M.; Manesiya, M.; Freedberg, M. V.; Hussain, S.

10.1101/2024.07.31.606022 — neuroscience — Posted on 2024-07-31

6 The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration

Walk, R.; Broz, K.; Jing, L.; Potter, R.; Gonzalez, C. E.; Beeve, A.; Scheller, E.; Gupta, M.; Setton, L.; Tang, S. Y.

10.1101/2024.07.12.603182 — bioengineering — Posted on 2024-07-31

7 CRISPR-Cas12a bends DNA to destabilize base pairs during target interrogation

Soczek, K. M.; Cofsky, J. C.; Tuck, O. T.; Shi, H.; Doudna, J. A.

10.1101/2024.07.31.606079 — biochemistry — Posted on 2024-07-31

8 The art of seeing the elephant in the room: 2D embeddings of single-cell data do make sense

Lause, J.; Kobak, D.; Berens, P.

10.1101/2024.03.26.586728 — genomics — Posted on 2024-07-31

9 Global conservation prioritization approach provides credible results at a regional scale

Roswell, M.; Espindola, A.

10.1101/2023.08.31.555788 — ecology — Posted on 2024-07-31

10 Glycogen homeostasis and mtDNA expression require motorneuron to muscle TGFβ/Activin Signaling in Drosophila

Bretscher, H.; O'Connor, M. B.

10.1101/2024.06.25.600699 — cell biology — Posted on 2024-07-31

11 BMP9 and BMP10 coordinate liver cellular crosstalk to maintain liver health

Zhao, D.; Huang, Z.; Li, X.; Wang, H.; Hou, Q.; Wang, Y.; Yan, F.; Yang, W.; Liu, D.; Yi, S.; Han, C.; Hao, Y.; Tang, L.

10.1101/2024.02.08.579542 — cell biology — Posted on 2024-07-31

12 Model-driven engineering of Yarrowia lipolytica for improved microbial oil production

Duman-Özdamar, Z. E.; Julsing, M. K.; Martins dos Santos, V. A. P.; Hugenholtz, J.; Suarez-Diez, M.

10.1101/2024.07.31.606002 — molecular biology — Posted on 2024-07-31

13 DNA-enhanced CuAAC ligand enables live-cell detection of intracellular biomolecules

Nian, K.; Liu, Y.; Qiu, Y.; Zhang, Z.; Brigandi, L.; Wanunu, M.; Rouhanifard, S. H.

10.1101/2022.11.10.515969 — molecular biology — Posted on 2024-07-31

14 Abundance, identity, and potential diazotrophic activity of nifH-containing organisms at marine cold seeps

Semler, A. C.; Paris, E. R.; Dekas, A. E.

10.1101/2024.07.31.606060 — microbiology — Posted on 2024-07-31

15 Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance

Dadonaite, B.; Ahn, J. J.; Ort, J. T.; Yu, J.; Furey, C.; Dosey, A.; Hannon, W. W.; Baker, A. V.; Webby, R. J.; King, N. P.; Liu, Y.; Hensley, S. E.; Peacock, T. P.; Moncla, L. H.; Bloom, J. D.

10.1101/2024.05.23.595634 — microbiology — Posted on 2024-07-31

16 IFNB induced by non-lytic virus immunotherapy promotes improved survival in hepatocellular carcinoma, mediated by MHCII-independent cytotoxic CD4+ T-cells

Hughes, R.; Moran, A.; Scott, K. J.; Appleton, E.; Bentham, M. J.; Ilett, E.; Melcher, A.; Macdonald, A.; Samson, A.; Griffin, S.

10.1101/2024.02.23.581738 — immunology — Posted on 2024-07-31

17 Phagosome-mediated activation of STING during diverse bacterial infections

Ragland, S. A.; Kagan, J. C.

10.1101/2022.10.28.514268 — immunology — Posted on 2024-07-31

18 T cells promote distinct transcriptional programs of cutaneous inflammatory disease in human skin structural cells

DeBerg, H. A.; Fahning, M. L.; Schlenker, J. D.; Schmitt, W. P.; Gratz, I. K.; Carlin, J. S.; Campbell, D. J.; Morawski, P. A.

10.1101/2024.07.31.606077 — immunology — Posted on 2024-07-31

19 Macrophage-fibroblast crosstalk drives Arg1-dependent lung fibrosis via ornithine loading

Yadav, P.; Gomez Ortega, J.; Tamaki, W.; Chien, C.; Chang, K.-C.; Biswas, N.; Pan, S.; Nilsson, J.; Yin, X.; Bhattacharyya, A.; Boostanpour, K.; Jujaray, T.; Wang, J.; Tsukui, T.; Sheppard, D.; Li, B.; Maishan, M.; Taenaka, H.; Matthay, M.; Muramatsu, R.; Maliskova, L.; Ghosh, A.; Eckalbar, W.; Molofsky, A. B.; Wolters, P. J.; Tamaki, S.; Bivona, T.; Abate, A. R.; Wagner, A.; Tharp, K.; Bhattacharya, M.

10.1101/2023.09.06.556606 — immunology — Posted on 2024-07-31

20 Neurexin 3 is Essential for the Specific Wiring of a Color Pathway in the Mammalian Retina

Kunze, V. P.; Angueyra, J. M.; Ball, J. M.; Thomsen, M. B.; Li, X.; Sabnis, A.; Nadal-Nicolas, F. M.; Li, W.

10.1101/2023.02.13.527055 — neuroscience — Posted on 2024-07-31

21 Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice

Hackwell, E. C. R.; Ladyman, S. R.; Clarkson, J.; McQullian, H. J.; Boehm, U.; Herbison, A. E.; Brown, R. S. E.; Grattan, D. R.

10.1101/2024.01.26.577359 — neuroscience — Posted on 2024-07-31

22 A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.

Tolossa, G. B.; Schneider, A. M.; Dyer, E. L.; Hengen, K. B.

10.1101/2024.07.11.603152 — neuroscience — Posted on 2024-07-31

23 An intrinsic hierarchical, retinotopic organization of pulvinar connectivity in the human neonate

Ayzenberg, V.; Song, C.; Arcaro, M.

10.1101/2024.07.30.605817 — neuroscience — Posted on 2024-07-31

24 B-BIND: Biophysical Bayesian Inference forNeurodegenerative Dynamics

Agrawal, A.; Rachleff, V. M.; Travaglini, K. J.; Mukherjee, S.; Crane, P. K.; Hawrylycz, M.; Keene, C. D.; Lein, E.; Mena, G. E.; Gabitto, M. I.

10.1101/2024.06.10.597236 — neuroscience — Posted on 2024-07-31

25 Establishing And Maintaining The Blood-Brain Barrier: Epigenetic And Signaling Determinants.

Pandit, P. K. T.; Sadanandan, J.; Thomas, S.; Mathew, I. E.; Huang, Z.; Blackburn, S. L.; Tandon, N.; Lokhande, H.; McCrea, P. D.; Bresnick, E. H.; Dash, P. K.; McBride, D. W.; Harmanci, A.; Ahirwar, L. K.; Jose, D.; Dienel, A. C.; Zeineddine, H. A.; Hong, S.

10.1101/2022.11.29.516809 — neuroscience — Posted on 2024-07-31

26 Top-down attention shifts behavioral and neural event boundaries in narratives with overlapping event scripts

De Soares, A.; Kim, T.; Mugisho, F.; Zhu, E.; Lin, A.; Zheng, C.; Baldassano, C.

10.1101/2023.08.08.552465 — neuroscience — Posted on 2024-07-31

27 Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's Disease

Raj, A.; Torok, J.; Ranasinghe, K.

10.1101/2024.03.05.583407 — neuroscience — Posted on 2024-07-31

28 Visual Congruency Modulates Music Reward through Sensorimotor Integration

Zhang, L.; Du, Y.; Zatorre, R.

10.1101/2024.07.30.605944 — neuroscience — Posted on 2024-07-31

29 Natural Selection in a Synthetic Yeast Endosymbiont Promotes Stable Coexistence

Supekova, L.; Zhou, H.; Barcellos, I. H.; Nguyen, C.; Dik, D. A.; Schultz, P. G.

10.1101/2024.07.31.606091 — synthetic biology — Posted on 2024-07-31

30 Root-specific secondary metabolism at the single-cell level: a case study of theanine metabolism and regulation in the roots of tea plants (Camellia sinensis)

Lin, S.; Zhang, Y.; Zhang, S.; Wei, Y.; Han, M.; Deng, Y.; Guo, J.; Zhu, B.; Yang, T.; Xia, E.; Wan, X.; Lucas, W.; Zhang, Z.

10.1101/2024.01.16.575853 — plant biology — Posted on 2024-07-31

31 Noncaloric monosaccharides induce excessive sprouting angiogenesis in zebrafish via foxo1a-marcksl1a signal

Wang, X.; Zhao, J.; Xu, J.; Li, B.; Liu, X.; Xie, G.; Duan, X.; Liu, D.

10.1101/2024.01.18.576182 — pharmacology and toxicology — Posted on 2024-07-31

32 Identifying interactions between TDP-43 N-terminal and RNA binding domains

Scott, D. D.; Jena, L.; Perez-Miller, S.; Kumirov, V.; Khanna, R.; Khanna, M.

10.1101/2024.07.31.604183 — biophysics — Posted on 2024-07-31

33 Discrete protein condensation events govern calcium signal dynamics in T cells

Morita, S.; O'Dair, M. K.; Groves, J. T.

10.1101/2024.07.31.606035 — biophysics — Posted on 2024-07-31

34 Capturing cell heterogeneity in representations of cell populations for image-based profiling using contrastive learning

van Dijk, R.; Arevalo, J.; Babadi, M.; Carpenter, A. E.; Singh, S.

10.1101/2023.11.14.567038 — bioinformatics — Posted on 2024-07-31

35 Voronoi spatial pattern construction through bacterial colony simulation

Moreno, D. V.; Ortiz, Y. M.; Araya, D. I.; Gutierrez, M. E.

10.1101/2024.07.31.606050 — bioengineering — Posted on 2024-07-31

36 Lymphatic endothelial cell-targeting lipid nanoparticles delivering VEGFC mRNA improve lymphatic function after injury

Michalaki, E.; Chin, R.; Jeong, K.; Qi, Z.; Liebman, L. N.; Gonzalez-Vargas, Y.; Echeverri, E. S.; Paunovska, K.; Muramatsu, H.; Pardi, N.; Tamburini, B. J.; Jakus, Z.; Dahlman, J. E.; Dixon, J. B.

10.1101/2024.07.31.605343 — bioengineering — Posted on 2024-07-31

37 Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy

Pakharukova, N.; Thomas, B. N.; Bansia, H.; Li, L.; Abzalimov, R. R.; Kim, J.; Kahsai, A. W.; Pani, B.; Bassford, D. K.; Liu, S.; Zhang, X.; des Georges, A.; Lefkowitz, R. J.

10.1101/2024.07.31.605623 — biochemistry — Posted on 2024-07-31

38 DNA stimulates SIRT6 to mono-ADP-ribosylate proteins within histidine repeats

Pederson, N. J.; Diehl, K. L.

10.1101/2024.07.31.606047 — biochemistry — Posted on 2024-07-31

39 Sex Dimorphism in Expression of Immune Response Genes in Drosophila

Khan, M. M.; Graze, R. M.

10.1101/2024.07.27.605461 — genetics — Posted on 2024-07-31

40 Cathelicidin antimicrobial peptides mediate immune protection of marsupial neonates

Park, J.; Ke, W.; Kaage, A.; Feigin, C. Y.; Pritykin, Y.; Donia, M. S.; Mallarino, R.

10.1101/2024.07.29.605640 — evolutionary biology — Posted on 2024-07-31

41 Regulatory networks of KRAB zinc finger genes and transposable elements changed during human brain evolution and disease

Chen, Y.-C.; Maupas, A.; Nowick, K.

10.1101/2023.12.18.569574 — evolutionary biology — Posted on 2024-07-31

42 Integrating metabolic scaling and coexistence theories

Saavedra, S.; Arroyo, J. I.; Deng, J.; Marquet, P. A.; Kempes, C. P.

10.1101/2023.02.28.530509 — ecology — Posted on 2024-07-31

43 YTHDC2 serves a distinct late role in spermatocytes during germ cell differentiation

Bailey, A. S.; Fuller, M. T.

10.1101/2023.01.23.525146 — developmental biology — Posted on 2024-07-31

44 Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics

Peshkin, L.; Daldello, E. M.; Van Itallie, E. S.; Sonnett, M.; Kreuzer, J.; Haas, W.; Kirschner, M. W.; Jessus, C.

10.1101/2024.07.26.605364 — developmental biology — Posted on 2024-07-31

45 Depletion of endomembrane reservoirs drives phagocytic appetite exhaustion in macrophages

Fountain, A.; Mansat, M.; Soffiaturo, S.; Gimenez, M. C.; Moussaoui, S.; Ezzo, M.; Verdawala, M. B.; Fung, K.; Lancaster, C.; Somerville, E.; Hinz, B.; Terebiznik, M.; Botelho, R. J.

10.1101/2024.07.31.605905 — cell biology — Posted on 2024-07-31

46 sMEK1 promotes crosstalk between IRE1 and Akt signaling pathway: Evidence for a novel IRE1/sMEK1/Akt complex

Qadri, O.; Bashir, S.; Banday, M.; Pal, D.; Fazili, K. M.

10.1101/2021.07.09.451832 — cell biology — Posted on 2024-07-31

47 mDia2 is an important mediator of MRTF-A-dependent regulation of breast cancer cell migration

Eder, I.; Yu, V.; Antonello, J.; Chen, F.; Gau, D.; Chawla, P.; Joy, M.; Lucas, P.; Boone, D.; LEE, A. V.; Roy, P.

10.1101/2023.12.21.572883 — cell biology — Posted on 2024-07-31

48 4D structural biology: quantitative dynamics in the eukaryotic RNA exosome complex

Liebau, J.; Lazzaretti, D.; Fuertges, T.; Bichler, A.; Pilsl, M.; Rudack, T.; Sprangers, R.

10.1101/2024.01.28.577622 — molecular biology — Posted on 2024-07-31

49 Non-genetic messenger RNA silencing reveals essential genes in phage-host interplay

Gerovac, M.; Thurica-Mitic, S.; Buhlmann, L.; Rech, V.; Zhu, Y.; Carien, S.; Popella, L.; Vogel, J.

10.1101/2024.07.31.605949 — molecular biology — Posted on 2024-07-31

50 Transcriptional regulation of adipocyte lipolysis by IRF2BP2

Chen, Y.; Liu, L.; Calhoun, R.; Cheng, L.; Merrick, D.; Steger, D.; Seale, P.

10.1101/2024.07.31.605689 — molecular biology — Posted on 2024-07-31

51 Identification of novel fructo-oligosaccharide bacterial consumers by pulse metatranscriptomics in a human stool sample

Prattico, C.; Gonzalez, E.; Dridi, L.; Jazestani, S.; Low, K.; Abbott, W.; Maurice, C. F.; Castagner, B.

10.1101/2024.07.31.606081 — microbiology — Posted on 2024-07-31

52 Comprehensive Assessment of Initial Adaptation of ESBL Positive ST131 Escherichia coli to Carbapenem Exposure

Shropshire, W. C.; Song, X.; Bremer, J.; Seo, S.; Rodriguez, S.; Anand, S. S.; Dinh, A. Q.; Bhatti, M. M.; Konovalova, A.; Arias, C. A.; Kalia, A.; Shamoo, Y.; Shelburne, S. A.

10.1101/2024.07.31.606066 — microbiology — Posted on 2024-07-31

53 Assessing the effects of warming and carbonate chemistry parameters on marine microbes in the Gulf of Mexico through basin-scale DNA metabarcoding

Anderson, S. R.; Silliman, K.; Barbero, L.; Gomez, F. A.; Stauffer, B. A.; Schnetzer, A.; Kelble, C. R.; Thompson, L. R.

10.1101/2024.07.30.605667 — microbiology — Posted on 2024-07-31

54 Dietary fiber content in clinical ketogenic diets modifies the gut microbiome and seizure resistance in mice

Ozcan, E.; Yu, K. B.; Dinh, L.; Lum, G.; Lau, K.; Hsu, J.; Arino, M.; Paramo, J.; Lopez-Romero, A.; Hsiao, E. Y.

10.1101/2024.07.31.606041 — microbiology — Posted on 2024-07-31

55 An IL-12 mRNA-LNP adjuvant enhances mRNA vaccine induced CD8+ T cell responses

Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Kedl, R.; Weissman, D.; Hunter, C. A.

10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-31

56 Diversity in Notch ligand-receptor signaling interactions

Kuintzle, R.; Santat, L. A.; Elowitz, M. B.

10.1101/2023.08.24.554677 — systems biology — Posted on 2024-07-31

57 Delivery of novel replicating vectors to Synechococcus sp. PCC 7002 via natural transformation of plasmid multimers

Kamoku, C.; Cooper, C.; Straub, A.; Miller, N.; Nielsen, D. R.

10.1101/2024.07.31.606084 — synthetic biology — Posted on 2024-07-31

58 Comparative Analysis of Antioxidant Activity, ROS, and Relative Water Content Between Red and Green Cabbage

Sojib, M. R.; Methela, N. J.; Das, B.; Siddique, M. N. A.; Sultana, S.; Karim, A.; Islam, R.; Jone, M. J. H.

10.1101/2024.07.27.605406 — plant biology — Posted on 2024-07-31

59 Genetic variation associated with plastic and homeostatic growth responses to drought in Arabidopsis

Ferrero-Serrano, A.; Assmann, S. M.

10.1101/2021.05.07.443185 — plant biology — Posted on 2024-07-31

60 Amortized template-matching of molecular conformations from cryo-electron microscopy images using simulation-based inference

Dingeldein, L.; Silva-Sanchez, D.; Evans, L.; D'Imprima, E.; Grigorieff, N.; Covino, R.; Cossio, P.

10.1101/2024.07.23.604154 — biophysics — Posted on 2024-07-31

61 Imputing abundance of over 2500 surface proteins from single-cell transcriptomes with context-agnostic zero-shot deep ensembles

Chen, R.; Zhou, J.; Chen, B.

10.1101/2024.07.31.605432 — bioinformatics — Posted on 2024-07-31

62 Active Learning-Assisted Directed Evolution

Yang, J.; Lal, R. G.; Bowden, J. C.; Astudillo, R.; Hameedi, M. A.; Kaur, S.; Hill, M.; Yue, Y.; Arnold, F. H.

10.1101/2024.07.27.605457 — bioengineering — Posted on 2024-07-31

63 A simple in vitro fermentation model to detect alterations in gut microbiota-dependent bile acid profiles

Zheng, W.; Bakker, W.; Baccaro, M.; Jin, M.; Wang, J.; Rietjens, I.

10.1101/2024.07.31.606071 — biochemistry — Posted on 2024-07-31

64 pH-Controlled chemoselective rapid azo-coupling reaction (CRACR) enables global profiling of serotonylation proteome in cancer cells

Zhang, N.; Wu, J.; Gao, S.; Peng, H.; Li, H.; Gibson, C.; Wu, S.; Zhu, J.; Zheng, Q.

10.1101/2024.05.10.593574 — biochemistry — Posted on 2024-07-31

65 Activation of the mitochondrial unfolded protein response regulates the formation of stress granules

Lopez-Nieto Jordana, M.; Sun, Z.; Relton, E.; Safakli, R.; Freibaum, B. D.; Taylor, J. P.; Ruggieri, A.; Smyrnias, I.; Locker, N.

10.1101/2023.10.26.564187 — cell biology — Posted on 2024-07-31

66 p110alpha-dependent hepatocyte signaling is critical for liver gene expression and its rewiring in MASLD

Regnier, M.; Polizzi, A.; Fougeray, T.; Fougerat, A.; Perrier, P.; Anderson, K.; Lippi, Y.; Smati, S.; Lukowicz, C.; Lasserre, F.; Fouche, E.; Huillet, M.; Rives, C.; Tramunt, B.; Naylies, C.; Garcia, G.; Rousseau-Bacquie, E.; Bertrand-Michel, J.; Canlet, C.; Chevolleau-Mege, S.; Debrauwer, L.; Heymes, C.; Burcelin, R.; Levade, T.; Gourdy, P.; Wahli, W.; Blum, Y.; Gamet-Payrastre, L.; Ellero-Simatos, S.; Guillermet-Guibert, J.; Hawkins, P.; Stephens, L.; Montagner, A.; Loiseau, N.; Guillou, H.

10.1101/2024.01.09.574858 — cell biology — Posted on 2024-07-31

67 Effects of two different compounds on seizure suppression using the zebrafish PTZ-seizure model

Fernandez, J. A. A.; de Moura, T. C.; Vila, S. F.; Gaytan, J. A. R.; Lopez-Diaz, I.; Learte-Aymami, S.; Vazquez, M. E.; Mayan, M. D.; Sanchez, L.; Maurer-Morelli, C. V.

10.1101/2024.07.29.605666 — neuroscience — Posted on 2024-07-31

68 Individual differences in spatial working memory strategies differentially reflected in the engagement of control and default brain networks

Purg Suljic, N.; Kraljic, A.; Rahmati, M.; Cho, Y. T.; Slana Ozimic, A.; Murray, J. D.; Anticevic, A.; Repovs, G.

10.1101/2023.07.07.548112 — neuroscience — Posted on 2024-07-31

69 Using SAFEPATH to Uncover a Novel Mechanism of Hepatotoxicity for Gefitinib

Hosseini-Gerami, L.; Masarone, S.; Lane, J.

10.1101/2024.07.31.605988 — systems biology — Posted on 2024-07-31

70 TET proteins regulate Drosha expression and impact microRNAs in iNKT cells

Gioulbasani, M.; Aijo, T.; Valenzuela, J. E.; Buquera Bettes, J.; Tsagaratou, A.

10.1101/2024.07.31.605991 — immunology — Posted on 2024-07-31

71 Complete sequencing of ape genomes

Yoo, D.; Rhie, A.; Hebbar, P.; Antonacci, F.; Logsdon, G. A.; Solar, S. J.; Antipov, D.; Pickett, B. D.; Safonova, Y.; Montinaro, F.; Luo, Y.; Malukiewicz, J.; Storer, J. M.; Lin, J.; Sequeira, A. N.; Mangan, R. J.; Hickey, G.; Anez, G. M.; Balachandran, P.; Bankevich, A.; Beck, C. R.; Biddanda, A.; Borchers, M.; Bouffard, G. G.; Brannan, E.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Chan, A. P.; Crawford, J.; Diekhans, M.; Engelbrecht, E.; Feschotte, C.; Formenti, G.; Garcia, G. H.; Gennaro, L. d.; Gilbert, D.; Green, R. E.; Guarracino, A.; Gupta, I.; Haddad, D.; Han, J.; Harris, R. S.; Hartley

10.1101/2024.07.31.605654 — genomics — Posted on 2024-07-31

72 PRMT7 mediated PTEN activation promotes bone formation in female mice

Zhang, Y.; Qing, J.; Li, Y.; Gao, X.; Lu, D.; Wang, Y.; Gu, L.; Zhang, H.; Li, Z.; Wang, X.; Zhou, Y.; Zhang, P.

10.1101/2024.07.31.605998 — developmental biology — Posted on 2024-07-31

73 Cascaded Antithetic Integral Feedback Motifs for Robust Stability and Performance Improvement

M. Zand, A.; Gupta, A.; Khammash, M.

10.1101/2024.07.31.605983 — synthetic biology — Posted on 2024-07-31

74 Encephalomyocarditis virus protein 2B* antagonises innate immune signalling by interacting with 14-3-3 protein family members

Nguyen, S. K.; Holmes, S.; Barrow, H. G.; Lukhovitskaya, N.; Jahun, A. S.; Georgana, I.; Caller, L. G.; Edgar, J. R.; Emmott, E.; Firth, A.; Stewart, H.

10.1101/2024.07.31.605952 — microbiology — Posted on 2024-07-31

75 Comparative analysis of the treatment-naive microbiome across rheumatic diseases to predict MTX treatment response

Amend, L.; Huang, K. D.; Sivapornnukul, P.; Rabenow, M.; Bielecka, A.; Wang, X.-Y.; Neumann-Schaal, M.; Witte, T.; Strowig, T.

10.1101/2024.07.31.605913 — microbiology — Posted on 2024-07-31

76 Citizen science informs demand-driven breeding of opportunity crops

Voss, R.; de Sousa, K.; N'Danikou, S.; Shango, A. J.; Aglinglo, L. A.; Laporte, M.-A.; Legba, E. C.; Houdegbe, A. C.; Diarra, D. d. Y.; Dolo, A.; Sidibe, A.; Ouedraogo, C. O.; Coulibaly, H.; Achigan-Dako, E. G.; Kileo, A.; Malulu, D.; Matumbo, Z.; Dinssa, F. F.; van Heerwaarden, J.; van Etten, J.; Riar, A.; van Zonneveld, M.

10.1101/2024.07.31.605211 — plant biology — Posted on 2024-07-31

77 Low-dose colchicine treatment improves vasorelaxation, reduces arterial remodeling and attenuates blood pressure increases in spontaneously hypertensive rats

Baldwin, S. N.; Bastrup, J. A.; van der Horst, J.; Formento, A. M. G.; Dubik, M.; Kudryavtseva, O. S.; Saljic, A.; Rognant, S.; Dannesboe, J.; Mozzicato, A. M.; Jespersen, T.; Moeller, J. B.; Tardif, J.-C.; Thomsen, M. B.; Jepps, T. A.

10.1101/2024.07.31.604256 — physiology — Posted on 2024-07-31

78 Coding of egocentric distance in the macaque ventral intraparietal area

Caziot, B.; Fathkhani, S.; Bremmer, F.

10.1101/2024.07.31.605976 — neuroscience — Posted on 2024-07-31

79 Dynorphin modulates motivation through a pallido-amygdala cholinergic circuit

Li, B.; Sun, Q.; Liu, M.; Guan, W.; Xiao, X.; Dong, C.; Bruchas, M.; Zweifel, L.; Li, Y.; Tian, L.

10.1101/2024.07.31.605785 — neuroscience — Posted on 2024-07-31

80 Modelling Protein-Glycan Interactions with HADDOCK

Ranaudo, A.; Giulini, M.; Pelissou Ayuso, A.; Bonvin, A. M.

10.1101/2024.07.31.605986 — bioinformatics — Posted on 2024-07-31

81 The Serine Shunt enables formate conversion to formaldehyde in vivo

Schann, K.; Wenk, S.

10.1101/2024.07.31.605843 — bioengineering — Posted on 2024-07-31

82 Quantitative Label-Free Single-Cell Proteomics on the Orbitrap Astral MS

Petrosius, V.; Aragon-Fernandez, P.; Arrey, T. N.; Woessmann, J.; Üresin, N.; de Boer, B.; Su, J.; Furtwängler, B.; Stewart, H.; Denisov, E.; Petzoldt, J.; Peterson, A. C.; Hock, C.; Damoc, E.; Makarov, A. A.; Zabrouskov, V.; Porse, B. T.; Schoof, E. M.

10.1101/2024.07.31.605978 — biochemistry — Posted on 2024-07-31

83 Proteome-wide quantification of inositol pyrophosphate-protein interactions

Richter, A.; Ruwolt, M.; Lampe, S.; Liu, F.; Furkert, D.; Fiedler, D.

10.1101/2024.07.31.606004 — biochemistry — Posted on 2024-07-31

84 Sex-chromosome-dependent aging in female heterogametic methylomes

Tangili, M.; Sudyka, J.; Furni, F.; Palsboll, P. J.; Verhulst, S.

10.1101/2024.07.31.605993 — evolutionary biology — Posted on 2024-07-31

85 Resource Quality Differentially Impacts Daphnia Interactions with Two Parasites

Fearon, M. L.; Sanchez, K. F.; Sun, S.-J.; Calhoun, S. K.; Monell, K. J.; Ravichandran, V.; Duffy, M. A.

10.1101/2024.07.31.605800 — ecology — Posted on 2024-07-31

86 HMCES corrupts replication fork stability during base excision repair in homologous recombination deficient cells

Pena-Gomez, M. J.; Rodriguez Martin, Y.; del Rio Oliva, M.; Masson, J.-Y.; Reyes, J. C.; Rosado, I. V.

10.1101/2024.07.31.605977 — molecular biology — Posted on 2024-07-31

87 Structural disconnections caused by white matter hyperintensities in post-stroke spatial neglect

Rohrig, L.; Karnath, H.-O.

10.1101/2024.07.31.605749 — neuroscience — Posted on 2024-07-31

88 The Computational Auditory Signal Processing and Perception Model (CASP): A Revised Version

Paulick, L. C.; Relano-Iborra, H.; Dau, T.

10.1101/2024.07.31.605576 — neuroscience — Posted on 2024-07-31

89 Contributions of genetic variation in astrocytes to cell and molecular mechanisms of risk and resilience to late onset Alzheimer's disease

Lee, H.; Pearse, R. V.; Lish, A. M.; Pan, C.; Augur, Z. M.; Terzioglu, G.; Gaur, P.; Liao, M.; Fujita, M.; Tio, E. S.; Duong, D. M.; Felsky, D.; Seyfried, N. T.; Menon, V.; Bennett, D. A.; De Jager, P. L.; Young-Pearse, T. L.

10.1101/2024.07.31.605928 — neuroscience — Posted on 2024-07-31

90 Gene transfer of human cardiomyopathy beta-MyHC mutant R403Qdirectly alters intact cardiac myocyte calcium homeostasis and causes hyper-contractility

Herron, T. J.; Devaney, E.; Guerrero-Serna, G.; Mundada, L.; Metzger, J. M.

10.1101/2024.07.31.605903 — physiology — Posted on 2024-07-31

91 Human PrP E219K as a new and promising substrate for RT-QuIC amplification of human prion strains: a first step towards strain discrimination

Marin-Moreno, A.; Reine, F.; Jaffrezic, F.; Herzog, L.; Rezaei, H.; Quadrio, I.; Haik, S.; Beringue, v.; Martin, D.

10.1101/2024.07.31.605973 — pathology — Posted on 2024-07-31

92 Machine Learning Reveals Key Glycoprotein Mutations and Rapidly Assigns Lassa Virus Lineages

Daodu, R. O.; Ulrich, J.-U.; Kuehnert, D.

10.1101/2024.07.31.605963 — bioinformatics — Posted on 2024-07-31

93 The ontogeny of chimpanzee technological efficiency

Berdugo, S.; Cohen, E.; Davis, A. J.; Matsuzawa, T.; Carvalho, S.

10.1101/2024.07.31.605100 — animal behavior and cognition — Posted on 2024-07-31

94 Optimal organelle inheritance strategies under different changing environments and mutational pressures

Garcia-Pascual, B.; Nordbotten, J.; Johnston, I.

10.1101/2024.07.31.605980 — evolutionary biology — Posted on 2024-07-31

95 Evolution of divergent daily temporal niches shaped by male-male competition can generate sympatric speciation

Bouinier, T.; Brunaud, A.; Smadi, C.; Llaurens, V.

10.1101/2024.07.31.601896 — evolutionary biology — Posted on 2024-07-31

96 Temperature drives seagrass recovery across the Western North Atlantic

Smulders, F.; Campbell, J.; Altieri, A.; Armitage, A.; Bakker, E.; Barry, S.; Becker, T.; Bethel, E.; Douglass, J.; van Duijnhoven, H.; de Fouw, J.; Frazer, T.; Glazner, R.; Goeke, J.; Gort, G.; Heck, K.; Kramer, O.; van de Leemput, I.; Manuel, S.; Martin, C.; Martinez Lopez, I.; McDonald, A.; Munson, C.; O'Shea, O.; Paul, V.; Reynolds, L.; Rhoades, K.; Rodriguez Bravo, L.; Sang, A.; Sawall, Y.; Smith, K.; Thompson, J.; van Tussenbroek, B.; Wied, W.; Christianen, M.

10.1101/2024.07.31.605761 — ecology — Posted on 2024-07-31

97 Silicone Wire Embolization-induced Acute Retinal Artery Ischemia and Reperfusion Model in Mouse: Gene Expression Provides Insight into Pathological Processes

Wang, Y.; Li, Y.; Feng, J.; Wang, C.; Wan, Y.; Lv, B.; Li, Y.; Xie, H.; Chen, T.; Wang, F.; Li, Z.; Yang, A.; Xiao, X.

10.1101/2024.05.01.592074 — neuroscience — Posted on 2024-07-31

98 CHANGES IN MUSCLE QUALITY FOLLOWING SHORT-TERM RESISTANCE TRAINING IN OLDER ADULTS: A COMPARISON OF ECHO INTENSITY AND TEXTURE ANALYSIS

Knowles, K. S.; Pagan, J. I.; Beausejour, J. P.; Mongold, S. J.; Anderson, A. W.; Stout, J. R.; Stock, M. S.

10.1101/2024.07.30.605815 — physiology — Posted on 2024-07-31

99 A synthetic human bone marrow extracellular matrix identifies tunnelling nanotubules as druggable mediators of functional cancer-niche crosstalk.

Hockney, S.; Parker, J.; Tzivelekis, B.; Blair, H.; Dalgarno, K.; Pal, D.

10.1101/2023.06.20.545732 — cancer biology — Posted on 2024-07-31

100 Nonlinear sound-sheet microscopy: imaging opaque organs at the capillary and cellular scale

Heiles, B.; Nelissen, F.; Terwiel, D.; Park, B. M.; Munoz Ibarra, E.; Matalliotakis, A.; Waasdorp, R.; Ara, T.; Barturen-Larrea, P.; Duan, M.; Shapiro, M. G.; Gazzola, V.; Maresca, D.

10.1101/2024.07.31.605825 — bioengineering — Posted on 2024-07-31

101 Introducing identification probability for automated and transferable assessment of metabolite identification confidence in metabolomics and related studies

Metz, T. O.; Chang, C. H.; Gautam, V.; Anjum, A.; Tian, S.; Wang, F.; Colby, S. M.; Nunez, J. R.; Blumer, M. R.; Edison, A. S.; Fiehn, O.; Jones, D. P.; Li, S.; Morgan, E. T.; Patti, G. J.; Ross, D. H.; Shapiro, M. R.; Williams, A. J.; Wishart, D. S.

10.1101/2024.07.30.605945 — biochemistry — Posted on 2024-07-31

102 Sex tweaks eye color

Bressan, P.

10.1101/2024.07.26.605233 — evolutionary biology — Posted on 2024-07-31

103 Delayed post-juvenile moult in malaria-infected European blackcaps

Remacha, C.; de la Hera, I.; Ramirez, A.; Perez-Tris, J.

10.1101/2024.07.31.605960 — ecology — Posted on 2024-07-31

104 An LNP-mRNA vaccine provides potent immunogenicity and protection against Mycobacterium tuberculosis

Lukeman, H.; Al-Wassiti, H.; Fabb, S. A.; Lim, L.; Wang, T.; Britton, W. J.; Steain, M.; Pouton, C. W.; Triccas, J.; Counoupas, C.

10.1101/2024.07.31.605765 — immunology — Posted on 2024-07-31

105 Cell-type-specific striatal modulation of amygdalar acetylcholine in salience assignment

Chen, A.; Li, Y.; Zhu, H.; Gu, H.; Weng, Y.; Xu, F.; Deng, H.; Xiao, X.

10.1101/2024.07.30.605919 — neuroscience — Posted on 2024-07-31

106 Cholecystokinin modulates age-dependent Thalamocortical Neuroplasticity

Li, X.; Feng, J.; Hu, X.; Zhou, P.; Chen, T.; Zheng, X.; Jendrichovsky, P.; Wang, X.; Chen, M.; Li, H.; Chen, X.; Zeng, D.; Zhang, M.; Xiao, Z.; He, L.; Bello, S. T.; He, J.

10.1101/2024.07.31.605964 — neuroscience — Posted on 2024-07-31

107 Enhanced and idiosyncratic neural representations of personally typical scenes

Wang, G.; Chen, L.; Cichy, R. M.; Kaiser, D.

10.1101/2024.07.31.605915 — neuroscience — Posted on 2024-07-31

108 Brain-responsive music enables non-invasive, targeted and unobtrusive neurostimulation

Zaaimi, B.; Clay, R.; Shivakumar, A.; Rickert, J.; Jackson, A.

10.1101/2024.07.30.605888 — neuroscience — Posted on 2024-07-31

109 How different immersive environments affect intracortical brain computer interfaces

Tortolani, A. F.; Kunigk, N. G.; Sobinov, A. R.; Boninger, M. L.; Bensmaia, S. J.; Collinger, J. L.; Hatsopoulos, N. G.; Downey, J. E.

10.1101/2024.07.30.605911 — neuroscience — Posted on 2024-07-31

110 Visual Congruency Modulates Music Reward through Sensorimotor Integration

Zhang, L.; Du, Y.; Zatorre, R.

10.1101/2024.07.30.605944 — neuroscience — Posted on 2024-07-31

111 Unsupervised learning as a computational principle works in visual learning of natural scenes, but not of artificial stimuli

Watanabe, T.; Sasaki, Y.; Ogawa, D.; Shibata, K.

10.1101/2024.07.31.605957 — neuroscience — Posted on 2024-07-31

112 PARP inhibition enhances exemestane efficacy in triple-negative breast cancer

Yusoh, N. A.; Su, L.; Chia, S. L.; Tian, X.; Ahmad, H.; Gill, M.

10.1101/2024.07.31.605956 — pharmacology and toxicology — Posted on 2024-07-31

113 Tumour-derived extracellular vesicles within the therapy-induced senescent secretome distinctly suppress breast cancer via DKK1-mediated inflammatory response.

Robert, M.; Jakhar, R.; Au, B. V.; Eng, G. W. L.; Wei, M.; Gao, A. K.; Chuah, Y. H.; Sachaphibulkij, K.; Bonne, I.; Lim, K. J.; Sinha, I.; Teh, D. B. L.; Lim, L. H. K.; Kumar, P.; Verma, N. K.; Sze, N. S. K.; Lim, E. H.; Ong, D. S. T.; Cheong, J. K.; Itahana, K.; Conolly, J. E.; Crasta, K. C.

10.1101/2024.03.29.586905 — cancer biology — Posted on 2024-07-31

114 Reinforced polymer-nanoparticle hydrogels for subcutaneous and sustained delivery of trastuzumab

Bovone, G.; Bernhard, S.; Jacquot, G.; Mittelheisser, V.; Mirjolet, C.; Guzzi, E. A.; Garau Paganella, L.; Liebi, L.; Lefebvre, O.; Goetz, J.; Charbonniere, L.; Harlepp, S.; Pivot, X.; Tibbitt, M. W.; Detappe, A.

10.1101/2024.07.30.605810 — bioengineering — Posted on 2024-07-31

115 Dual-color micro-LEDs integrated neural interface for multi-control optogenetic electrophysiology

Voroslakos, M.; Ko, E.; Yoon, E.; Buzsaki, G.

10.1101/2024.07.30.605927 — bioengineering — Posted on 2024-07-31

116 Optimizing Bioprocessing Efficiency with OptFed: Dynamic Nonlinear Modeling Improves Product-to-Biomass Yield by 19%

Schloegel, G.; Lueck, R.; Kittler, S.; Spadiut, O.; Kopp, J.; Zanghellini, J.; Gotsmy, M.

10.1101/2024.07.31.605953 — bioengineering — Posted on 2024-07-31

117 Development of an Organ-on-a-Chip for Correlative Microscopy: Visualizing Early Osteogenesis in 3D with High Resolution

Schaart, J. M.; Wasserberg, D.; Eufrasio Cruz, M. A.; Kea-te Lindert, M.; Van der Meijden, R. H. M.; Roverts, R.; Debera, N. D.; Lu, M. P.; Rouwkema, J.; Nijhuis, W. H.; van der Meer, A. D.; Jonkheijm, P.; Sommerdijk, N.; Akiva, A.

10.1101/2024.07.31.605958 — bioengineering — Posted on 2024-07-31

118 Personality assessment of synanthropic rhesus macaques: implications and challenges

Gill, T.; Gautam, A.; Massen, J. J. M.; Bhattacharjee, D.

10.1101/2024.07.30.605931 — animal behavior and cognition — Posted on 2024-07-31

119 Lineage-specific patterns of sexually dimorphic antennal transcription in the paper wasp Polistes fuscatus

Legan, A. W.; Sheehan, M. J.

10.1101/2024.07.30.605902 — evolutionary biology — Posted on 2024-07-31

120 The Neuropeptide Sulfakinin, a peripheral regulator of insect behavior switch between mating and foraging

Li, H.-F.; Dong, B.; Peng, Y.-Y.; Luo, H.-Y.; Ou, X.-L.; Ren, Z.-L.; Park, Y.; Wang, J.-J.; Jiang, H.

10.1101/2024.07.30.605941 — ecology — Posted on 2024-07-31

121 An outline on the chemical phenotype flexibility of forest species: an eco-metabolomics study of Pinus uncinata along an altitudinal gradient

Rivas Ubach, A.; Aranda, I.; Sardans, J.; Liu, Y.; Diaz de Quijano, M.; Pasa-Tolic, L.; Oravec, M.; Urban, O.; Penuelas, J.

10.1101/2024.07.31.605974 — ecology — Posted on 2024-07-31

122 Ciliary biology intersects autism and congenital heart disease

Teerikorpi, N.; Lasser, M. C.; Wang, S.; Kostyanovskaya, E.; Bader, E.; Sun, N.; Dea, J.; Nowakowski, T. J.; Willsey, A. J.; Willsey, H.

10.1101/2024.07.30.602578 — developmental biology — Posted on 2024-07-31

123 The effect of norepinephrine on ovarian dysfunction by mediating ferroptosis in mice model

hong, h.; Xiao, C.; Weng, l.; Wang, Q.; Lai, D.

10.1101/2024.07.30.605932 — molecular biology — Posted on 2024-07-31

124 Mechanism of neurodegeneration mediated by clonal inflammatory microglia

Vicario, R.; Fragkogianni, S.; Pokrovskii, M.; Mayer, C.; Lopez-Rodrigo, E.; Hu, Y.; Ogishi, M.; Alberdi, A.; Baako, A.; Ay, O.; Plu, I.; Sazdovitch, V.; Heritier, S.; Cohen-Aubart, F.; Shor, N.; Miyara, M.; Nguyen-Khac, F.; Viale, A.; Idbaih, A.; Amoura, Z.; Rosenblum, M.; Zhang, H.; Karnoub, E.-R.; Sashittal, P.; Jakatdar, A.; Iacobuzio-Donahue, C. A.; Abdel-Wahab, O.; Tabar, V.; Socci, N. D.; Elemento, O.; Diamond, E.; Boisson, B.; Casanova, J.-L.; Seilhean, D.; Haroche, J.; Donadieu, J.; Geissmann, F.

10.1101/2024.07.30.605867 — immunology — Posted on 2024-07-31

125 A novel and potent MICA/B antibody is therapeutically effective in KRAS LKB1 mutant lung cancer models

Kowash, R. R.; Sabnani, M.; Gray, L. T.; Deng, Q.; Girard, L.; Naito, Y.; Masahiro, K.; Minna, J. D.; Gerber, D. E.; Koyama, S.; Liu, Z. L.; Baruah, H.; Akbay, E. A.

10.1101/2024.07.30.605880 — immunology — Posted on 2024-07-31

126 Capillary connections between sensory circumventricular organs and adjacent parenchyma enable local volume transmission

Yao, Y.; Chen, Y.; Tomer, R.; Silver, R.

10.1101/2024.07.30.605849 — neuroscience — Posted on 2024-07-31

127 Muscarinic receptor activation preferentially inhibits rebound in vulnerable dopaminergic neurons

Beaver, M. L.; Evans, R. C.

10.1101/2024.07.30.605819 — neuroscience — Posted on 2024-07-31

128 It's the Sound not the Pulse: Peripheral Magnetic Stimulation Reduces Central Sensitization through Auditory Modulatory Effects

Abssy, S.; Osborne, N. R.; Osokin, E. E.; Tomin, R.; Honigman, L.; Khan, J. S.; De Vera, N.; Furman, A. J.; Mazaheri, A.; Seminowicz, D. A.; Moayedi, M.

10.1101/2024.07.30.605813 — neuroscience — Posted on 2024-07-31

129 Dynamic network features of functional and structural brain networks support visual working memory in aging adults

Neudorf, J.; Shen, K.; McIntosh, A. R.

10.1101/2024.07.30.605891 — neuroscience — Posted on 2024-07-31

130 Opioid-Induced Inter-regional Dysconnectivity Correlates with Analgesia in Awake Mouse Brains

Mariani, J.-C.; Diebolt, S.; Beynac, L.; Santos, R.; Schulz, S.; Deffieux, T.; Tanter, M.; LENKEI, Z.; Kliewer, A.

10.1101/2024.07.30.604249 — neuroscience — Posted on 2024-07-31

131 Spreading depolarizations exhaust neuronal ATP in a model of cerebral ischemia

Schoknecht, K.; Baeza-Lehnert, F.; Hirrlinger, J.; Dreier, J. P.; Eilers, J.

10.1101/2024.07.30.605834 — neuroscience — Posted on 2024-07-31

132 CIB2 function is distinct from Whirlin in the development of cochlear stereocilia staircase pattern

Giese, A. P. J.; Parker, A.; Rehman, S.; Brown, S. D. M.; Riazuddin, S.; Vander Kooi, C. W.; Bowl, M. R.; Ahmed, Z. M.

10.1101/2024.07.30.605852 — neuroscience — Posted on 2024-07-31

133 Subjective salience ratings are a reliable proxy for physiological measures of arousal

Hadjis, G. E.; Atlas, L. Y.; Mustafa, R.; McAndrews, M. P.; Moayedi, M.

10.1101/2024.07.30.605866 — neuroscience — Posted on 2024-07-31

134 Effects of unconscious tactile stimuli on autonomic nervous activity and afferent signal processing

Sakuragi, M.; Tanaka, Y.; Shinagawa, K.; Tsuji, K.; Umeda, S.

10.1101/2024.07.30.605926 — neuroscience — Posted on 2024-07-31

135 Event-marked Windowed Communication: Inferring activity propagation from neural time series

Madan Mohan, V.; Varley, T. F.; Cash, R.; Seguin, C.; Zalesky, A.

10.1101/2024.07.30.605466 — neuroscience — Posted on 2024-07-31

136 Sleep homeostasis in lizards and the role of cortex

Hatori, S.; Yamaguchi, S. T.; Kobayashi, R.; Matsui, F.; Zhou, Z.; Norimoto, H.

10.1101/2024.07.31.605950 — neuroscience — Posted on 2024-07-31

137 MLCK/MLCP regulates mammalian axon regeneration via the redistribution of the growth cone F-actin

None, S.; Wang, W.; Ma, J.; Yin, Y.; Ma, Y.

10.1101/2024.07.30.605892 — physiology — Posted on 2024-07-31

138 Phosphorylation of Zearalenone retains its toxicity

Asaduzzaman, M.; Pavlov, I. A.; St-Jean, G.; Zhu, Y.; Castex, M.; Chorfi, Y.; del Castillo, J. R. E.; Zhou, T.; Alassane-Kpembi, I.

10.1101/2024.07.30.605906 — pharmacology and toxicology — Posted on 2024-07-31

139 Insights into Therapeutic Discovery Through the Kelch Domain Structure of Keap1 at Ambient Temperature

YILMAZ, M.; SEVER, B.; KUTLU, Y.; GUL, M.; OKUDUCU, C.; TAVLI, S.; OTSUKA, M.; FUJITA, M.; HALILOGLU, T.; CIFTCI, H.; Demirci, H.

10.1101/2024.07.30.605796 — biophysics — Posted on 2024-07-31

140 Scaling and Merging Time-Resolved Laue Data with Variational Inference

Zielinski, K. A.; Dolamore, C.; Wang, H. K.; Henning, R. W.; Wilson, M. A.; Pollack, L.; Srajer, V.; Hekstra, D. R.; Dalton, K. M.

10.1101/2024.07.30.605871 — biophysics — Posted on 2024-07-31

141 The Extracellular Matrix Limits Nanoparticle Diffusion and Cellular Uptake in a Tissue-Specific Manner

Cahn, D.; Stern, A.; Buckenmeyer, M. J.; Wolf, M.; Duncan, G.

10.1101/2024.07.30.605895 — bioengineering — Posted on 2024-07-31

142 Receptor Binding Specificity of a Bovine A(H5N1) Influenza Virus

Chopra, P.; Page, C. K.; Shepard, J. D.; Ray, S. D.; Kandeil, A.; Jeevan, T.; Bowman, A. S.; Ellebedy, A. H.; Webby, R. J.; de Vries, R. P.; Tompkins, S. M.; Boons, G.-J.

10.1101/2024.07.30.605893 — biochemistry — Posted on 2024-07-31

143 Video Foundation Models for Animal Behavior Analysis

Sun, J. J.; Zhou, H.; Zhao, L.; Yuan, L.; Seybold, B.; Hendon, D.; Schroff, F.; Ross, D. A.; Adam, H.; Hu, B.; Liu, T.

10.1101/2024.07.30.605655 — animal behavior and cognition — Posted on 2024-07-31

144 A nonlinear relationship between prediction errors and learning rates in human reinforcement learning

Ikwunne, B.; Parham, J.; Pulcu, E.

10.1101/751222 — neuroscience — Posted on 2024-07-31

145 Expanding the space of self-reproducing RNAs using probabilistic generative models

Lambert, C. N.; Opuu, V.; Calvanese, F.; Zamponi, F.; Hayden, E. J.; Weigt, M. J.; Smerlak, M.; Nghe, P.

10.1101/2024.07.31.605758 — biochemistry — Posted on 2024-07-31

146 Thrombospondin-1 inhibits alternative complement pathway activation in vasculitis synergistically to factor H

Konwar, S.; Schroda, S.; Kleindienst, J.; Decker, E. L.; Pohl, M.; Zieger, B.; Panse, J.; Wang, H.; Grosse, R.; Rogg, M.; Schell, C. L.; Vidal, S.; Liu, X.; Gorzelanny, C.; Tschongov, T.; Haeffner, K.

10.1101/2024.07.31.606000 — molecular biology — Posted on 2024-07-31

147 Ganoderma lucidum alleviates kidney aging by modulating gut microbiota

Liu, X.; Zhao, J.; Liu, J.; Huang, Y.; Deng, W.; Yan, L.; Liu, X.; Cui, M.; Xiao, H.

10.1101/2024.07.30.605752 — microbiology — Posted on 2024-07-31

148 Loss of RREB1 reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes

Yu, G. Z.; Krentz, N. A. J.; Bentley, L.; Zhao, M.; Paphiti, K.; Sun, H.; Honecker, J.; Nygard, M.; Dashti, H.; Bai, Y.; Reid, M.; Thaman, S.; Wabitsch, M.; Rajesh, V.; Yang, J.; Mattis, K. K.; Abaitua, F.; Casero, R.; Hauner, H.; Knowles, J. W.; Wu, J. Y.; Mandrup, S.; Claussnitzer, M.; Svensson, K. J.; Cox, R. D.; Gloyn, A. L.

10.1101/2024.07.30.605923 — physiology — Posted on 2024-07-31

149 Central activation of catecholamine-independent lipolysis drives the end-stage catabolism of all adipose tissues

Zhang, X.; Majumdar, A.; Kim, C.; Kleiboeker, B.; Magee, K. L.; Learman, B. S.; Thomas, S. A.; Lodhi, I. J.; MacDougald, O. A.; Scheller, E. L.

10.1101/2024.07.30.605812 — physiology — Posted on 2024-07-31

150 Ketomimetic Nutrients Trigger a Dual Metabolic Defense in Breast Cancer Cells

Kamra, M.; Chen, Y.-I.; Delgado, P.; Seeley, E.; Seidlits, S.; YEH, H.-C.; Brock, A.; Parekh, S. H.

10.1101/2024.07.03.601966 — cancer biology — Posted on 2024-07-31

151 A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries

Masuda, R.; Thant, K. P. P.; Kawahara, K.; Oki, H.; Kadonosono, T.; Kobayashi, Y.; Koide, T.

10.1101/2023.11.14.567114 — biochemistry — Posted on 2024-07-31

152 Carbohydrate-active enzymes from Akkermansia muciniphila breakdown mucin O-glycans to completion

Crouch, L. I.; Bakshani, C. R.; Ojuri, T. O.; Pilgaard, B.; Holck, J.; McInnes, R.; Zakhour, M.; Kerouedan, M.; Newton, E.; Bolam, D. N.; Kozak, R. P.; Cakaj, S.

10.1101/2024.03.27.586211 — biochemistry — Posted on 2024-07-31

153 Understanding ecological adaptation in the microorganism Tetrahymena pyriformis through the lens of energy allocation

Perna, A.; Rivoli, E. S.; Perkins, D. M.

10.1101/2023.07.25.550219 — ecology — Posted on 2024-07-31

154 Iron transport pathways in the human malaria parasite Plasmodium falciparum revealed by RNA-sequencing

Wunderlich, J.; Kotov, V.; Votborg-Novel, L.; Ntalla, C.; Geffken, M.; Peine, S.; Portugal, S.; Strauss, J.

10.1101/2024.04.18.590068 — cell biology — Posted on 2024-07-31

155 Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence

Sanchez-Martinez, R.; Arani, A.; Krupovic, M.; Weitz, J. S.; Santos, F.; Anton, J.

10.1101/2024.07.30.605759 — microbiology — Posted on 2024-07-31

156 The antifungal capacity of a 681-membered collection of environmental yeast isolates

Macia Valero, A.; Tabatabaeifar, F.; Billerbeck, S.

10.1101/2024.07.29.605670 — microbiology — Posted on 2024-07-31

157 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system

Pulvirenti, N.; Righetti, C.; Clemente, F.; Serafini, B.; Pietroboni, A.; Galeota, E.; Rosicarelli, B.; Cordiglieri, C.; Iannone, C.; de Riz, M.; Vasco, C.; Espadas de Arias, A.; De Feo, T.; Valenti, L.; Prati, D.; Abrignani, S.; Gerosa, M.; Caporali, R.; Galimberti, D.; Scarpini, E.; Geginat, J.

10.1101/2024.07.30.605745 — immunology — Posted on 2024-07-31

158 Modelling variability in functional brain networks using embeddings

Huang, R.; Gohil, C.; Woolrich, M. W.

10.1101/2024.01.29.577718 — neuroscience — Posted on 2024-07-31

159 Molecular architecture of the altered cortical complexity in autism

Mamat, M.; Chen, Y.; Shen, W.; Li, L.

10.1101/2024.07.28.605533 — neuroscience — Posted on 2024-07-31

160 Circadian regulation of endoplasmic reticulum calcium response in cultured mouse astrocytes

Ryu, J. E.; Shim, K.-W.; Roh, H. W.; Park, M.; Lee, J.-H.; Kim, E. Y.

10.1101/2024.02.02.578616 — neuroscience — Posted on 2024-07-31

161 Immune Digital Twin Blueprint: A Comprehensive Mechanistic Model of the Human Immune System

Amin, R.; Aghamiri, S.; Puniya, B. L.; Mayo, L.; Startsev, D.; Poore, K.; Helikar, R. M.; Helikar, T.

10.1101/2020.03.11.988238 — systems biology — Posted on 2024-07-31

162 Defense-related callose synthase PMR4 promotes root hair callose deposition and adaptation to phosphate deficiency in Arabidopsis thaliana

Okada, K.; Yachi, K.; Nguyen, T. A. N.; Kanno, S.; Yasuda, S.; Tadai, H.; Tateda, C.; Lee, T.-H.; Nguyen, U.; Inoue, K.; Tsuchida, N.; Ishihara, T.; Miyashima, S.; Hiruma, K.; Miwa, K.; Maekawa, T.; Notaguchi, M.; Saijo, Y.

10.1101/2023.07.05.547890 — plant biology — Posted on 2024-07-31

163 Microtubule-based nucleation results in a large sensitivity to cell geometry of the plant cortical array

Saltini, M.; Deinum, E. E.

10.1101/2024.03.25.586463 — biophysics — Posted on 2024-07-31

164 EmbedGEM: A framework to evaluate the utility of embeddings for genetic discovery

Mukherjee, S.; McCaw, Z. R.; Pei, J.; Merkoulovitch, A.; Tandon, R.; Soare, T. W.; Amar, D.; Somineni, H.; Klein, C.; Satapati, S.; Lloyd, D.; Probert, C.; Insitro Research Team, ; Koller, D.; O'Dushlaine, C.; Karaletsos, T.

10.1101/2023.11.24.568344 — bioinformatics — Posted on 2024-07-31

165 Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis Thaliana populations

Gibbs, P.; Paril, J.; Fournier-Level, A.

10.1101/2024.07.09.601435 — genetics — Posted on 2024-07-31

166 ALPHA: A High Throughput System for Quantifying Growth In Aquatic Plants

Robinson, K. A.; Augoustides, V.; Madenyika, T.; Sartor, R. C.

10.1101/2024.07.30.605820 — plant biology — Posted on 2024-07-31

167 Aging and Germination of Long-term Stored Seeds: Can MicroRNAs Unlock the Secrets?

Boczkowska, M.; Puchta-Jasinska, M.; Bolc, P.; Groszyk, J.

10.1101/2024.07.30.605790 — plant biology — Posted on 2024-07-31

168 Myeloid-Specific Thrombospondin-1 Deficiency Exacerbates Aortic Rupture via Broad Suppression of Extracellular Matrix Proteins

Zhou, T.; Yang, H.; Assa, C.; DeRoo, E.; Bontekoe, J.; Burkel, B.; Ponik, S. M.; Lu, H. S.; Daugherty, A.; Liu, B.

10.1101/2024.07.30.605216 — pathology — Posted on 2024-07-31

169 RESP2: An uncertainty aware multi-target multi-property optimization AI pipeline for antibody discovery

Parkinson, J.; Hard, R.; Ko, Y. S.; Wang, W.

10.1101/2024.07.30.605700 — bioinformatics — Posted on 2024-07-31

170 Extending the capabilities of deconvolution to provide cell type specific pathway analysis of bulk RNA-seq data for idiopathic pulmonary fibrosis

Calvero, M.-R.; Meghadri, S. H.; Carleo, A.; Prasse, A.; DeLuca, D. S.

10.1101/2024.07.30.605740 — bioinformatics — Posted on 2024-07-31

171 A survey of ADP-ribosyltransferase families in the pathogenic Legionella

Krysinska, M.; Gradowski, M.; Baranowski, B.; Pawlowski, K.; Dudkiewicz, M.

10.1101/2024.07.30.605764 — bioinformatics — Posted on 2024-07-31

172 A replicable and modular benchmark for long-read transcript quantification methods

Zare Jousheghani, Z.; Singh, N. P.; Patro, R.

10.1101/2024.07.30.605821 — bioinformatics — Posted on 2024-07-31

173 Logan: Planetary-Scale Genome Assembly Surveys Life's Diversity

Chikhi, R.; Raffestin, B.; Korobeynikov, A.; Edgar, R. C.; Babaian, A.

10.1101/2024.07.30.605881 — bioinformatics — Posted on 2024-07-31

174 Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution

Tong, H.; Guo, X.; Jacques, M.; Luo, Q.; EYNON, N.; Teschendorff, A.

10.1101/2024.07.30.605833 — bioinformatics — Posted on 2024-07-31

175 Genomic and transcriptomic analyses of Heteropoda venatoria reveal the expansion of P450 family for starvation resistance in spider

Zhang, G.; Wang, Y.; Jiang, H.; Wang, Y.

10.1101/2024.07.31.605936 — bioinformatics — Posted on 2024-07-31

176 Annotation Vocabulary (Might Be) All You Need

Hallee, L.; Rafailidis, N.; Horger, C.; Hong, D.; Gleghorn, J. P.

10.1101/2024.07.30.605924 — bioinformatics — Posted on 2024-07-31

177 A rapid CAT transformation protocol and nuclear transgene expression tools for metabolic engineering in Cyanidioschyzon merolae 10D

Villegas-Valencia, M.; Stark, M. R.; Seger, M.; Wellman, G. B.; Overmans, S.; Lammers, P. J.; Rader, S. D.; Lauersen, K. J.

10.1101/2024.07.30.605877 — bioengineering — Posted on 2024-07-31

178 A Novel Computational Pre-Procedural Planning Model for Coronary Interventions Based on Coronary CT Angiography

lyu, m.; liang, c.; zhang, x.; li, q.; ryo, t.; ventikos, y.; chen, d.

10.1101/2024.07.29.605713 — bioengineering — Posted on 2024-07-31

179 A Bayesian Hierarchical Model of Trial-to-Trial Fluctuations in Decision Criterion

Vloeberghs, R.; Urai, A. E.; Desender, K.; Linderman, S. W.

10.1101/2024.07.30.605869 — animal behavior and cognition — Posted on 2024-07-31

180 Honey bulk DNA metagenomic analysis to identify honey biological composition and monitor honeybee pathogens

Paluoja, P.; Krjutskov, K.; Salumets, A.; Raime, K.

10.1101/2024.07.31.605955 — genomics — Posted on 2024-07-31

181 Mechanistic origin and preimplantation development of uniparental and polyploid blastomeres

Zhao, Y.; Fernandez-Montoro, A.; Peeters, G.; Jatsenko, T.; De Coster, T.; Angel-Velez, D.; Lefevre, T.; Voet, T.; Tsuiko, O.; Kurg, A.; Smits, K.; Van Soom, A.; Vermeesch, J. R.

10.1101/2024.07.30.605883 — genetics — Posted on 2024-07-31

182 Effect of assortative mating and sexual selection on polygenic barriers to gene flow

Surendranadh, P.; Sachdeva, H.

10.1101/2024.07.30.605898 — genetics — Posted on 2024-07-31

183 wQFM-TREE: highly accurate and scalable quartet-based species tree inference from gene trees

Rafi, A.; Rumi, A. M. S.; Hakim, S. A.; Sohaib, S.; Tahmid, M. T.; Momin, R. J. I.; Zaman, T. A.; Reaz, R.; Bayzid, M. S.

10.1101/2024.07.30.605630 — evolutionary biology — Posted on 2024-07-31

184 ERGA-BGE genome of Valencia hispanica (Valenciennes, 1826): a critically endangered Iberian toothcarp

Ventura, M.; Franch, N.; Fernandez, R.; Palma-Guerrero, J.; Böhne, A.; Monteiro, R.; Aguilera, L.; Gut, M.; Alioto, T. S.; Camara Ferreira, F.; Cruz, F.; Gomez-Garrido, J.; Haggerty, L.; Martin, F.; Brown, T.

10.1101/2024.07.31.604920 — evolutionary biology — Posted on 2024-07-31

185 Method and timing of rhizobacteria inoculation to plant roots alters success and strength of aphid suppression

Blenkinsopp, S.; Henderson, M.; Zytynska, S. E.

10.1101/2024.07.30.605806 — ecology — Posted on 2024-07-31

186 A laboratory method for simulating the effects of subsequent fires on pyrogenic organic matter at different exposure depths in a sand matrix

Luo, M.; Yedinak, K.; Bourne, K.; Whitman, T.

10.1101/2024.07.30.605814 — ecology — Posted on 2024-07-31

187 An effective model for community-based conservation around authorized fishing settlements inside a devolved Wildlife Management Area in southern Tanzania

Duggan, L. M.; Tarimo, L. J.; Walsh, K. A.; Kavishe, D. R.; Crego, R. D.; Elisa, M.; Mombo, F.; Butler, F.; Killeen, G.

10.1101/2024.07.30.605829 — ecology — Posted on 2024-07-31

188 Zebrafish Foxl2l functions in proliferating germ cells for female meiotic entry

Yang, C.-H.; Wang, Y.-W.; Hsu, C.-w.; Pan, Y.-J.; Chung, B.-c.

10.1101/2024.07.30.605757 — developmental biology — Posted on 2024-07-31

189 Bacteria combine polar- and dispersed-growth to power cell elongation and wall width dynamics

Zambri, M. P.; Baglio, C. R.; Irazoki, O.; Jones, S. E.; Garner, E. C.; Cava, F.; Elliot, M. A.

10.1101/2024.07.30.605496 — microbiology — Posted on 2024-07-31

190 Structural insights into the assembly mechanism of the flagellar MS-ring with three different symmetries

Kinoshita, M.; Makino, F.; Miyata, T.; Imada, K.; Namba, K.; Minamino, T.

10.1101/2024.07.30.605930 — microbiology — Posted on 2024-07-31

191 Enhanced detection for antibiotic resistance genes in wastewater samples using CRISPR-enriched metagenomic method

Mao, Y.; Shisler, J. L.; Nguyen, T. H.

10.1101/2024.07.30.605462 — microbiology — Posted on 2024-07-31

192 Addressing Underestimation of Waterborne Disease Risks Due to Fecal Indicator Bacteria Bound in Aggregates

Angelescu, D. E.; Abi-Saab, D.; Ganaye, R.; Wanless, D.; Wong, J.

10.1101/2024.07.31.605961 — microbiology — Posted on 2024-07-31

193 Isolation and characterization of cell wall and extracellular polysaccharides from cultures of the mycoparasitic strain Tirochoderma koningiopsis

Nowak, A.; Wlizło, K.; Komaniecka, I.; Szymanska-Chargot, M.; Zdunek, A.; Kapral-Piotrowska, J.; Tyskiewicz, K.; Jaroszuk-Sciseł, J.

10.1101/2024.07.31.605896 — microbiology — Posted on 2024-07-31

194 Quorum sensing employs a dual regulatory mechanism to repress T3SS gene expression

Paul, P.; Podicheti, R.; Geyman, L.; Papenfort, K.; van Kessel, J. C.

10.1101/2024.07.30.605901 — microbiology — Posted on 2024-07-31

195 Intracellular accumulation of free cholesterol in macrophages triggers a PARP1 response to DNA damage and PARP1 impairs lipopolysaccharide-induced inflammatory response

Ting, K.; Ibrahim, H.; Cybulsky, M.

10.1101/2024.07.30.605465 — immunology — Posted on 2024-07-31

196 Circulating mucosal-like IgA responses associate with severity of Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome

Cabrera, L.; Buckner, C.; Martinez, V.; Maki, S.; Vapalahti, O.; Vaheri, A.; Hepojoki, J.; Tietavainen, J.; Makela, S.; Mustonen, J.; Strandin, T.

10.1101/2024.07.30.605778 — immunology — Posted on 2024-07-31

197 Transcriptomic analysis of the functions of CSF1R-dependent macrophages in postnatal development in the rat

Carter-Cusack, D.; Huang, S.; Keshvari, S.; Patkar, O.; Sehgal, A.; Allavena, R.; Byrne, R.; Morgan, P.; Bush, S. J.; Summers, K. M.; Irvine, K. M.; Hume, D. A.

10.1101/2024.07.30.605701 — immunology — Posted on 2024-07-31

198 Cortical Acetylcholine Response to Deep Brain Stimulation of the Basal Forebrain

Shanazz, K.; Xie, K.; Oliver, T.; Bogan, J.; Vale Diaz, F.; Sword, J.; Kirov, S. A.; Terry, A.; O'Herron, P.; Blake, D. T.

10.1101/2024.07.30.605828 — neuroscience — Posted on 2024-07-31

199 Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice

Khan, T.; McFall, D. J.; Hussain, A. I.; Frayser, L. A.; Casilli, T. P.; Steck, M. C.; Sanchez Brualla, I.; Kuehn, N. M.; Cho, M.; Barnes, J. A.; Harris, B. T.; Vicini, S.; Forcelli, P. A.

10.1101/2024.07.30.605784 — neuroscience — Posted on 2024-07-31

200 Enhancer AAVs for targeting spinal motor neurons and descending motor pathways in rodents and macaque

Kussick, E.; Johansen, N.; Taskin, N.; Wynalda, B.; Martinez, R.; Groce, E. L.; Reding, M.; Liang, E.; Shulga, L.; Huang, C.; Casper, T.; Clark, M.; Ho, W.; Gao, Y.; van Velthoven, C. T. J.; Sobieski, C.; Ferrer, R.; Berg, M. R.; Curtis, B. C.; English, C.; Day, J. C.; Fortuna, M.; Donadio, N.; Newman, D.; Yao, S.; Chakka, A. B.; Goldy, J.; Torkelson, A.; Guzman, J. B.; Chakrabarty, R.; Nguy, B.; Guilford, N.; Pham, T. H.; Wright, V.; Ronellenfitch, K.; Gudsnuk, K.; Thyagarajan, B.; Smith, K. A.; Dee, N.; Zeng, H.; Yao, Z.; Tasic, B.; Levi, B. P.; Hodge, R.; Bakken, T. E.; Lein, E. S.; Ting, J

10.1101/2024.07.30.605864 — neuroscience — Posted on 2024-07-31

201 A computational model of altered neuronal activity in altered gravity

Gontier, C.; Kalinski, L.; Striebel, J.; Sturm, M.; Meerholz, Z.; Schunk, S.; Lichterfeld, Y.; Liemersdorf, C.

10.1101/2024.07.30.605832 — neuroscience — Posted on 2024-07-31

202 The big tau splice isoform resists Alzheimer's-related pathological changes

Chung, D.-e. C.; Deng, X.; Yalamanchili, H. K.; Revelli, J.-P.; Han, A. L.; Tadros, B.; Richman, R.; Dias, M.; Alavi Naini, F.; Boeynaems, S.; Hyman, B. T.; Zoghbi, H. Y.

10.1101/2024.07.30.605685 — neuroscience — Posted on 2024-07-31

203 Interactive effects of temperature acclimation and dietary fatty acids on metabolic rate and body composition of zebra finches (Taeniopygia guttata)

Campbell, M. J.; Mastromonaco, G. F.; Burness, G.

10.1101/2024.07.30.604977 — zoology — Posted on 2024-07-31

204 Transcriptome profiling of maize transcription factor mutants to probe gene regulatory network predictions

Ellison, E. L.; Zhou, P.; Chu, Y.-H.; Hermanson, P.; Gomez-Cano, L.; Myers, Z. A.; Abnave, A.; Gray, J.; Hirsch, C. N.; Grotewold, E.; Springer, N. M.

10.1101/2024.07.30.605884 — plant biology — Posted on 2024-07-31

205 Discovery of chemical marker for maidong (roots of Ophiopogon japonicus and Liriope spicata): a feature-based molecular networking approach

Lei, F.; Saldanha, L. L.; Weckerle, C.; Bigler, L.

10.1101/2024.07.30.605840 — plant biology — Posted on 2024-07-31

206 Disrupted Nitric Oxide Homeostasis Impacts Fertility Through Multiple Processes Including Protein Quality Control

Treffon, P.; Vierling, E.

10.1101/2024.07.30.605885 — plant biology — Posted on 2024-07-31

207 Unraveling cysteine deficiency-associated rapid weight loss

Varghese, A.; Gusarov, I.; Gamallo-Lana, B.; Dolgonos, D.; Mankan, Y.; Shamovsky, I.; Phan, M.; Jones, R.; Gomez-Jenkins, M.; White, E.; Wang, R.; Jones, D.; Papagiannakopoulos, T.; Pacold, M. E.; Mar, A. C.; Littman, D. R.; Nudler, E.

10.1101/2024.07.30.605703 — physiology — Posted on 2024-07-31

208 Experimental Infection of greater white-toothed Shrews (Crocidura russula) with Borna disease virus 1: Insights into Viral Spread and Shedding

Nobach, D.; Raeder, L.; Mueller, J.; Herzog, S.; Eickmann, M.; Herden, C.

10.1101/2024.07.30.605894 — pathology — Posted on 2024-07-31

209 Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment

Ranard, K. M.; Appel, B.

10.1101/2024.07.30.605803 — developmental biology — Posted on 2024-07-30

210 An intrinsic hierarchical, retinotopic organization of pulvinar connectivity in the human neonate

Ayzenberg, V.; Song, L.; Arcaro, M.

10.1101/2024.07.30.605817 — neuroscience — Posted on 2024-07-30

211 Unique longitudinal contributions of sulcal interruptions to reading acquisition in children

Bouhali, F.; Dubois, J.; Hoeft, F.; Weiner, K. S.

10.1101/2024.07.30.605574 — neuroscience — Posted on 2024-07-30

212 Event boundaries drive norepinephrine release and distinctive neural representations of space in the rodent hippocampus

McKenzie, S.; Sommer, A. L.; Pimentel, I.; Kakani, M.; Choi, I. J.; Newman, E. L.; English, D. F.

10.1101/2024.07.30.605900 — neuroscience — Posted on 2024-07-30

213 MRI signatures of cortical microstructure in human development align with oligodendrocyte cell-type expression

Genc, S.; Ball, G.; Chamberland, M.; Raven, E. P.; Tax, C. M.; Ward, I.; Yang, J. Y.; Palombo, M.; Jones, D. K.

10.1101/2024.07.30.605934 — neuroscience — Posted on 2024-07-30

214 Embryological insights into the evolution of genome regulation using haploid and diploid whiteflies, Bemisia tabaci

Shelby, E. A.; McKinney, E. C.; Simmons, A.; Moore, A. J.; Moore, P. J.

10.1101/2024.07.30.605827 — developmental biology — Posted on 2024-07-30

215 Hypersynchronous iPSC-derived SHANK2 neuronal networks are rescued by mGluR5 agonism

McCready, F. P.; Pradeepan, K. S.; Khaki, M.; Wei, W.; Matusiak, N.; Piekna, A.; Martinez-Trujillo, J. C.; Ellis, J.

10.1101/2024.07.30.605451 — neuroscience — Posted on 2024-07-30

216 Aggregation Dynamics of a 150 kDa Aβ42 Oligomer: Insights from Cryo Electron Microscopy and Multimodal Analysis

Kamalaldinezabadi, S. S.; Watzlawik, J. O.; Rosenberry, T. L.; Paravastu, A. K.; Stagg, S. M.

10.1101/2024.07.30.605873 — biophysics — Posted on 2024-07-30

217 AncFlow: An Ancestral Sequence Reconstruction Approach for Determining Novel Protein Structural

Rouzbehani, R.; Kelley, S. T.

10.1101/2024.07.30.605920 — bioinformatics — Posted on 2024-07-30

218 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery

Umansky, T.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.

10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-07-30

219 Enzymatic synthesis of isotopically labeled hydrogen peroxide for mass spectrometry-based applications

Hoare, M.; Tan, R.; Militi, I.; Welle, K. A.; Swovick, K.; Hryhorenko, J. R.; Ghaemmaghami, S.

10.1101/2024.07.30.605865 — biochemistry — Posted on 2024-07-30

220 Multi-omics approaches define novel aphid effector candidates associated with virulence and avirulence phenotypes

Thorpe, P.; Altmann, S.; Lopez-Cobollo, R.; Douglas, N.; Iqbal, J.; Kanvil, S.; Simon, J.-C.; Carolan, J. C.; Bos, J.; Turnbull, C.

10.1101/2024.07.30.605808 — genomics — Posted on 2024-07-30

221 CRISPR-mediated chromosome deletion facilitates genetic mapping of Vip3Aa resistance gene within complex genomic region in an invasive global pest

Jin, M.; Shan, Y.; Peng, Y.; Chen, S.; Zhou, X.; Liu, K.; Xiao, Y.

10.1101/2024.07.30.605831 — genetics — Posted on 2024-07-30

222 RNA tertiary structure and conformational dynamics revealed by BASH MaP

Oleynikov, M.; Jaffrey, S. R.

10.1101/2024.04.11.589009 — molecular biology — Posted on 2024-07-30

223 Histone H2B Monoubiquitylation Regulates Elongation-to-Termination Transition in RNA Polymerase II Transcription

Bandyopadhyay, T.; Basu, B.; Parua, P. K.

10.1101/2024.07.27.605434 — molecular biology — Posted on 2024-07-30

224 Enhanced RNAi does not provide efficient innate antiviral immunity in mice in vivo.

Kulmann, M. I. R.; Taborska, E.; Benkoova, B.; Palus, M.; Drobek, A.; Horvat, F.; Pasulka, J.; Malik, R.; Salyova, E.; Honig, V.; Pellerova, M.; Borsanyiova, M.; Stepanek, O.; Bopegamage, S.; Ruzek, D.; Svoboda, P.

10.1101/2024.07.29.605661 — molecular biology — Posted on 2024-07-30

225 Metabolic alterations drive inflammatory phenotypes in CHIP-associated heart failure

Mansouri, S.; Hemmerling, I.; Hesami, G.; Cremer, S.; Kirschbaum, K.; Klatt, S.; Behjati, F.; Schulz, M. H.; Li, X.; Scheller, M.; Mueller-Tidow, C.; Arndt, P.; Guenther, S.; Nandigama, M.-S.; Looso, M.; A. Rieger, M.; Kuhnert, S.; Vogelmeier, C. F.; Bals, R.; Fleming, I.; Zeiher, A.; Seeger, W.; Leuschner, F.; Savai, R.; Dimmeler, S.; Pullamsetti, S. S.

10.1101/2024.07.30.605744 — molecular biology — Posted on 2024-07-30

226 The integrated stress response regulates 18S nonfunctional rRNA decay in mammals

Coria, A. R.; Shah, A.; Shafieinour, M.; Taylor, S. J.; Guiblet, W.; Miller, J. T.; Mani Sharma, I.; Wu, C. C.-C.

10.1101/2024.07.30.605914 — molecular biology — Posted on 2024-07-30

227 A detailed protocol for generating spike trans-complemented SARS-CoV-2 replicons

Yang, Q.; Manicassamy, B.; Neelamegham, S.

10.1101/2024.07.28.605443 — microbiology — Posted on 2024-07-30

228 Closing the genome of Teredinibacter turnerae T7902 by long-read nanopore sequencing

Gasser, M. T.; Liu, A.; Flatau, R.; Altamia, M. A.; Filone, C. M.; Distel, D. L.

10.1101/2024.07.30.605897 — microbiology — Posted on 2024-07-30

229 In situ deposition of nanobodies by an engineered commensal microbe promotes survival in a mouse model of enterohemorrhagic E. coli

Srivastava, R.; Gonzalez-Prieto, C.; Lynch, J.; Muscolo, M.; Lin, C.; Brown, M. A.; Lemos, L.; Shrestha, A.; Osburne, M.; Leong, J. M.; Lesser, C. F.

10.1101/2024.07.30.605899 — microbiology — Posted on 2024-07-30

230 HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest

Ghone, D.; Evans, E.; Bandini, M.; Stephenson, K. G.; Sherer, N. M.; Suzuki, A.

10.1101/2024.07.30.605839 — microbiology — Posted on 2024-07-30

231 Characterization of bronchiolitis and vaccine-induced enhanced respiratory disease in Syrian hamsters caused by respiratory syncytial virus infection

Zhao, B.; Zhang, G.; Wu, J.; Ding, X.; Wei, X.; Peng, W.; Rong, N.; Yang, H.; Liu, J.

10.1101/2024.07.30.605875 — microbiology — Posted on 2024-07-30

232 Multiplicity of Type 6 Secretion System toxins limits the evolution of resistance

Smith, W. P. J.; Armstrong-Bond, E.; Coyte, K. Z.; Knight, C.; Basler, M.; Brockhurst, M.

10.1101/2024.07.30.605577 — microbiology — Posted on 2024-07-30

233 Proteomic changes orchestrate metabolic acclimation of a unicellular diazotrophic cyanobacterium during light-dark cycle and nitrogen fixation states

Panda, P.; Giri, S. J.; Sherman, L. A.; Kihara, D.; Aryal, U. K.

10.1101/2024.07.30.605809 — microbiology — Posted on 2024-07-30

234 Identification of Glyoxalase A in Group B Streptococcus and its contribution to methylglyoxal tolerance and virulence

Akbari, M. S.; Joyce, L. R.; Spencer, B. L.; McIver, K. S.; Doran, K. S.

10.1101/2024.07.30.605887 — microbiology — Posted on 2024-07-30

235 Episomal virus maintenance enables bacterial population recovery from infection and virus-bacterial coexistence

Sanchez-Martinez, R.; Arani, A.; Krupovic, M.; Weitz, J. S.; Santos, F.; Anton, J.

10.1101/2024.07.30.605759 — microbiology — Posted on 2024-07-30

236 Modular small RNA drives the emergence of virulence traits and environmental trade-offs in Vibrio cholerae

Balasubramanian, D.; Crist, C.; Almagro-Moreno, S.

10.1101/2024.07.30.605856 — microbiology — Posted on 2024-07-30

237 Dynamics of antimicrobial resistance and virulence of Salmonella enterica serovar Dublin

Sia, C. M.; Ambrose, R. L.; Valcanis, M.; Andersson, P.; Ballard, S. A.; Howden, B. P.; Williamson, D. A.; Pearson, J. S.; Ingle, D. J.

10.1101/2024.07.30.605691 — microbiology — Posted on 2024-07-30

238 Assessing the effects of warming and carbonate chemistry parameters on marine microbes in the Gulf of Mexico through basin-scale DNA metabarcoding

Anderson, S. R.; Silliman, K.; Barbero, L.; Gomez, F. A.; Stauffer, B. A.; Schnetzer, A.; Kelble, C. R.; Thompson, L. R.

10.1101/2024.07.30.605667 — microbiology — Posted on 2024-07-30

239 Understanding the Transfer and Persistence of Antimicrobial Resistance in Aquaculture Using a Model Teleost Gut System

Barcan, A. S.; Humble, J. L.; Kasaragod, S.; Sajib, M. S. I.; Barcan, R. A.; McGinnity, P.; Welch, T. J.; Robertson, B.; Vamanu, E.; Bagigalupo, A. E.; Llewellyn, M. S.; Samsing, F.

10.1101/2024.07.30.605792 — microbiology — Posted on 2024-07-30

240 Commensal-pathogen dynamics structure disease outcomes during Clostridioides difficile colonization

Fishbein, S.; DeVeaux, A. L.; Khanna, S.; Ferreiro, A. L.; Liao, J.; Agee, W.; Ning, J.; Mahmud, B.; Wallace, M. J.; Hink, T.; Reske, K. A.; Guruge, J.; Leekha, S.; Dubberke, E. R.; Dantas, G.

10.1101/2024.07.11.603094 — microbiology — Posted on 2024-07-30

241 Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior

Perich, M. G.; Conti, S.; Badi, M.; Bogaard, A.; Barra, B.; Rajan, K.; Bloch, J.; Courtine, G.; Micera, S.; Capogrosso, M.; Milekovic, T.

10.1101/2020.07.30.228767 — neuroscience — Posted on 2024-07-30

242 Harnessing CRISPR interference to re-sensitize laboratory strains and clinical isolates to last resort antibiotics

Frusteri Chiacchiera, A.; Casanova, M.; Bellato, M.; Piazza, A.; Migliavacca, R.; Batt, G.; Magni, P.; Pasotti, L.

10.1101/2024.07.30.604783 — synthetic biology — Posted on 2024-07-30

243 The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors

Ubah, O. C.; Lake, E. W.; Priyanka, S.; Shi, K.; Moeller, N. H.; Porter, A. J.; Aihara, H.; LeBeau, A. M.; Barelle, C. J.

10.1101/2024.07.30.605874 — pharmacology and toxicology — Posted on 2024-07-30

244 Unlocking the Potential: FKK6 as a Microbial Mimicry Based Therapy for Chronic Inflammation-Associated Colorectal Cancer in a Murine Model

Sladekova, L.; Li, H.; DesMarais, V. M.; Beck, A. P.; Guzik, H.; Vyhlidalova, B.; Gu, H.; Mani, S.; Dvorak, Z.

10.1101/2024.07.30.605845 — pharmacology and toxicology — Posted on 2024-07-30

245 Cell-type-specific Labeling of Endogenous Proteins Using the Split GFP System in Drosophila

Inal, M. A.; Banzai, K.; Kamiyama, R.; Kamiyama, D.

10.1101/2024.05.06.592806 — cell biology — Posted on 2024-07-30

246 An IL-12 mRNA-LNP adjuvant enhances mRNA-LNP vaccine induced CD8+ T cell responses

Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Weissman, D.; Hunter, C. A.

10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-30

247 Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques

Bosinger, S. E.; Edwards, C. T.; Karunakaran, K. A.; Garcia, E.; Beutler, N.; Gagne, M.; Golden, N.; Aoued, H.; Pellegrini, K.; Burnett, M. R.; Honeycutt, C. C.; Lapp, S. A.; Ton, T.; Lin, M. C.; Metz, A.; Bombin, A.; Goff, K.; Scheuermann, S. E.; Wilkes, A.; Wood, J. S.; Ehnert, S.; Weissman, S.; Curran, E. H.; Moore, I. N.; Roy, M.; Dessasau, E.; Paiardini, M.; Upadhyay, A. A.; Maness, N. J.; Douek, D. C.; Piantadosi, A.; Andrabi, R.; Rogers, T. R.; Burton, D. R.

10.1101/2024.07.30.605768 — immunology — Posted on 2024-07-30

248 Immunodominant extracellular loops of Treponema pallidum FadL outer membrane proteins elicit antibodies with opsonic and growth-inhibitory activities

Delgado, K. N.; Caimano, M. J.; Orbe, I. C.; Vicente, C. F.; LaVake, C. J.; Grassmann, A. A.; Moody, M. A.; Radolf, J. D.; Hawley, K. L.

10.1101/2024.07.30.605823 — immunology — Posted on 2024-07-30

249 Mapping protein conformational landscapes from crystallographic drug fragment screens

Saeed, A. A.; Klureza, M. A.; Hekstra, D. R.

10.1101/2024.07.29.605395 — biophysics — Posted on 2024-07-30

250 A resource for comparing AF-Cluster and other AlphaFold2 sampling methods

Wayment-Steele, H. K.; Ovchinnikov, S.; Colwell, L.; Kern, D.

10.1101/2024.07.29.605333 — biophysics — Posted on 2024-07-30

251 Cryo-EM Structure of Salmonella typhimurium ArnC; the Key Enzyme in Lipid-A Modification Conferring Polymyxin Resistance

Patel, D. H.; Karimullina, E.; Guo, Y.; Semper, C.; Patel, D. T.; Emde, T.; Borek, D.; Savchenko, A.

10.1101/2024.07.30.605912 — biochemistry — Posted on 2024-07-30

252 Blended Genome Exome (BGE) as a Cost Efficient Alternative to Deep Whole Genomes or Arrays

DeFelice, M.; Grimsby, J.; Howrigan, D.; Yuan, K.; Chapman, S. B.; Stevens, C.; DeLuca, S.; Townsend, M.; Buxbaum, J.; Pericak-Vance, M. A.; Qin, S.; Stein, D. J.; Teferra, S.; Xavier, R.; Huang, H.; Martin, A.; Neale, B.

10.1101/2024.04.03.587209 — genomics — Posted on 2024-07-30

253 Genome structural variants shape adaptive success of an invasive urban malaria vector Anopheles stephensi

Samano, A.; Kumar, N.; Liao, Y.; Ishtiaq, F.; Chakraborty, M.

10.1101/2024.07.29.605641 — evolutionary biology — Posted on 2024-07-30

254 Microbial community function increases host plant leaf growth in a pitcher plant experimental system

Bernardin, J. R.; Young, E. B.; Gray, S. M.; Bittleston, L. S.

10.1101/2024.01.30.578016 — ecology — Posted on 2024-07-30

255 INO80 regulates chromatin accessibility to facilitate suppression of sex-linked gene expression during mouse spermatogenesis

Chakraborty, P.; Magnuson, T.

10.1101/2023.01.04.522761 — developmental biology — Posted on 2024-07-30

256 Dissociable neuronal modules in the orbitofrontal cortex representing single and multi-attribute choice tasks

Xu, C.; Ni, K.; Cai, X.

10.1101/2022.07.02.498538 — neuroscience — Posted on 2024-07-30

257 Hypersensitivity controlled by mir-9a modulates female receptivity of Drosophila melanogaster.

Zhang, X.; Bagley, J. A.; Huang, Y.; Kim, W. J.

10.1101/2024.07.29.605583 — neuroscience — Posted on 2024-07-30

258 Establishing And Maintaining The Blood-Brain Barrier: Epigenetic And Signaling Determinants.

10.1101/2022.11.29.516809 — neuroscience — Posted on 2024-07-30

259 Clinical prediction of wound re-epithelisation outcomes in non-severe burn injury using the plasma lipidome

Ryan, M. J.; Raby, E.; Masuda, R.; Lodge, S.; Nitschke, P.; Maker, G. L.; Wist, J.; Fear, M. W.; Holmes, E.; Nicholson, J.; Gray, N.; Whiley, L.; Wood, F. M.

10.1101/2023.07.28.550938 — systems biology — Posted on 2024-07-30

260 Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis.

Hammouri, D.; Orwick, A.; Doll, M.; Sanchez Vega, D.; Shah, P. P.; Clarke, C. J.; Clem, B.; Beverly, L. J.; Siskind, L. J.

10.1101/2024.07.29.605635 — physiology — Posted on 2024-07-30

261 Novel gramicidin-derived ????-helical antimicrobialpeptides

Lambden, E.; Wallace, M. I.; Ulmschneider, M. B.

10.1101/2023.12.31.573784 — biophysics — Posted on 2024-07-30

262 A Unified Framework to Analyze Transposable Element Insertion Polymorphisms using Genome-graphs

Groza, C.; Chen, X.; Wheeler, T. J.; Bourque, G.; Goubert, C.

10.1101/2023.09.11.557209 — bioinformatics — Posted on 2024-07-30

263 Wearable Disposable Electrotherapy

FallahRad, M.; Chaudhry, Z.; Belali Koochesfahani, M.; Bhuiyan, R.; Zaman, M.; Liu, T.; Saha, K.; Diaz Uraga, M. R.; Thahsin, M.; Donnery, K.; Babaev, B.; Saw, M.; Rddad, A.; Velarde, O.; Couzis, A.; Bikson, M.

10.1101/2023.11.28.569062 — bioengineering — Posted on 2024-07-30

264 Molecular insight into the Drosophila piRNA pathway network through a combination of systematic protein interaction screening and structural prediction

Salgania, H. K.; Metz, J.; Lingren, E.; Bleischwitz, C.; Hauser, D.; Oliveras Mate, K.; Bollack, D.; Lahr, F.; Garbelyanski, A.; Jeske, M.

10.1101/2024.05.31.596839 — biochemistry — Posted on 2024-07-30

265 Adaptive loss of tRNA gene expression leads to phage resistance in a marine cyanobacterium

Zborowsky, S.; Tahan, R.; Lindell, D.

10.1101/2024.04.25.591146 — microbiology — Posted on 2024-07-30

266 Regulatory T-cells in multiple sclerosis are activated by Epstein-Barr Virus and produce IL-10 in the central nervous system

10.1101/2024.07.30.605745 — immunology — Posted on 2024-07-30

267 ComBatLS: A location- and scale-preserving method for multi-site image harmonization

Gardner, M.; Shinohara, R.; Bethlehem, R. A. I.; Romero Garcia, R.; Warrier, V.; Dorfschmidt, L.; Lifespan Brain Chart Consortium, ; Shanmugan, S.; Thompson, P.; Seidlitz, J.; Alexander-Bloch, A.; Chen, A.

10.1101/2024.06.21.599875 — neuroscience — Posted on 2024-07-30

268 Characterizing the Spatial Distribution of Dendritic RNA at Single Molecule Resolution

Kim, J.; Rosario, J.; Mendoza, E.; Kuang, D.; Kim, J.

10.1101/2024.07.18.602927 — neuroscience — Posted on 2024-07-30

269 The frontal cortex adjusts striatal integrator dynamics for flexible motor timing

Yang, Z.; Inagaki, M.; Gerfen, C.; Fontolan, L.; Inagaki, H. K.

10.1101/2024.06.29.601348 — neuroscience — Posted on 2024-07-30

270 Pigment-dispersing factor neuropeptides act as multifunctional hormones and modulators in tardigrades

Dutta, S.; Hering, L.; Grollmann, M. M.; Metzendorf, N.; Gross, V.; Arakawa, K.; Neupert, S.; Stengl, M.; Herberg, F. W.; Mayer, G.

10.1101/2024.07.30.605422 — zoology — Posted on 2024-07-30

271 Jukes-Cantor Correction for Phylogenetic Tree Reconstruction

Emunefe, F. G.; Ugbene, I. J.

10.1101/2024.07.30.605767 — systems biology — Posted on 2024-07-30

272 Charting Taxa in Amanita Section Amidella (Basidiomycota : Amanitaceae)

Oliveira, P.; Arraiano-Castilho, R.

10.1101/2024.07.30.605754 — evolutionary biology — Posted on 2024-07-30

273 Harnessing Community Science and Open Research-based Data to Track Distributions of Invasive Species in Japan

Sakai, S.; Atsumi, K.; Genroku, T.; Goka, K.; Fujiki, S.

10.1101/2024.07.30.605772 — ecology — Posted on 2024-07-30

274 Derivation of aerial insect concentration with a 94 GHz FMCW cloud radar

Lochmann, M.; Kalesse-Los, H.; Haest, B.; Vogl, T.; van Klink, R.; Addison, F.; Maahn, M.; Schimmel, W.; Wirth, C.; Quaas, J.

10.1101/2024.07.30.605781 — ecology — Posted on 2024-07-30

275 Structural Basis of betaKNL2 Centromeric Targeting Mechanism and Its Role in Plant-Specific Kinetochore Assembly

Yadala, R.; Camara, A. S.; Yalagapati, S. P.; Jaroschinsky, P.; Meitzel, T.; Ariyoshi, M.; Fukagawa, T.; Rutten, T.; Bui, T. T. G.; Lermontova, I.

10.1101/2024.07.30.605747 — molecular biology — Posted on 2024-07-30

276 The phenotype of SMC6_G514R hinge mutant of Physcomitrium patents

Angelis, K. J.; Hola, M.; Vagnerova, R.; Vaculikova, J.; Palecek, J. J.

10.1101/2024.07.29.605668 — molecular biology — Posted on 2024-07-30

277 The role of the synaptic vesicle protein SV2A in regulating mitochondrial morphology and autophagy.

Joerg, M.; Reichert, J. S.; Pauly, K.; Distler, U.; Tenzer, S.; Bartholome, O.; Rogister, B.; Kern, A.; Behl, C.; Gelleri, M.; Ritz, S.; Cremer, C. M.; Peslalz, P.; Plietker, B.; Friedland, K.

10.1101/2024.07.30.605753 — molecular biology — Posted on 2024-07-30

278 Lasso peptides sviceucin and siamycin I have anti-virulence activity and restore vancomycin effectiveness in vancomycin-resistant Enterococcus sp. and Staphylococcus aureus

Boudrioua, A.; Baëtz, B.; Desmadril, S.; Goulard, C.; Groo, A.-C.; Lombard, C.; Gueulle, S.; Marugan, M.; Malzert-Freon, A.; Hartke, A.; Li, Y.; Giraud, C.

10.1101/2024.07.30.605797 — microbiology — Posted on 2024-07-30

279 Diversification of Pseudomonas aeruginosa biofilm populations under repeated phage exposures decreases the efficacy of the treatment

Martinet, M. G.; Lohde, M.; Higazy, D.; Brandt, C.; Pletz, M. W.; Middelboe, M.; Makarewicz, O.; Ciofu, O.

10.1101/2024.07.30.602193 — microbiology — Posted on 2024-07-30

280 Rapid neutralizing assay for circulating H5N1 influenza virus in dairy cows

Miyakawa, K.; Ota, M.; Sano, K.; Momose, F.; Okura, T.; Kishida, N.; Arita, T.; Suzuki, Y.; Shirakura, M.; Asanuma, H.; Watanabe, S.; Ryo, A.; Hasegawa, H.

10.1101/2024.07.30.605731 — microbiology — Posted on 2024-07-30

281 The malaria parasite PP1 phosphatase controls the initiation of the egress pathway of asexual blood-stages by regulating the rounding-up of the vacuole

Seveno, M.; Loubens, M. N.; Berry, L.; Graindorge, A.; Lebrun, M.; Lavazec, C.; Lamarque, M. H.

10.1101/2024.07.30.605770 — microbiology — Posted on 2024-07-30

282 Second impact of an acute total body irradiation on thymic epithelial cells

Namiki, K.; Muramatsu, W.; Miyao, T.; Ishii, H.; Endo, R.; Hagiwara, N.; Miyauchi, M.; Yoshida, M.; Akiyama, N.; Akiyama, T.

10.1101/2024.07.30.605780 — immunology — Posted on 2024-07-30

283 MIND WANDERING DURING IMPLICIT LEARNING IS ASSOCIATED WITH INCREASED PERIODIC EEG ACTIVITY AND IMPROVED EXTRACTION OF HIDDEN PROBABILISTIC PATTERNS

Simor, P.; Vekony, T.; Farkas, B. C.; Szalardy, O.; Bogdany, T.; Brezoczki, B.; Csifcsak, G.; Nemeth, D.

10.1101/2024.07.30.605743 — neuroscience — Posted on 2024-07-30

284 Interaural level difference sensitivity in neonatally deafened rats fitted with bilateral cochlear implants

Buchholz, S.; Schnupp, J. W.; Arndt, S.; Rosskothen-Kuhl, N.

10.1101/2024.07.30.605756 — neuroscience — Posted on 2024-07-30

285 Healthy aging delays and dedifferentiates high-level visual representations

Haupt, M.; Garrett, D. D.; Cichy, R. M.

10.1101/2024.07.30.605732 — neuroscience — Posted on 2024-07-30

286 The representational nature of spatio-temporal recurrent processing in visual object recognition

Xie, S.; Singer, J. J. D.; Yilmaz, B.; Kaiser, D.; Cichy, R. M.

10.1101/2024.07.30.605751 — neuroscience — Posted on 2024-07-30

287 Genome-based discovery of pachysiphine synthases in Tabernaemontana elegans

Lezin, E.; Durand, M.; Birer Williams, C.; Lopez Vazquez, A. L.; Perrot, T.; Gautron, N.; Petrignet, J.; Cuello, C.; Jansen, H.; Magot, F.; Szwarc, S.; Le Pogam, P.; Beniddir, M.; Koudounas, K.; Oudin, A.; St-Pierre, B.; Giglioli-Guivarc'h, N.; Sun, C.; Papon, N.; Krogh Jensen, M.; Dirks, R.; O'Connor, S.; Besseau, S.; Courdavault, V.

10.1101/2024.07.30.605783 — plant biology — Posted on 2024-07-30

288 Water availability determines plant regeneration fates

Kareem, A.; van Wullen, A. K.; Zhang, A.; Walckiers, G.; Fasth, E.; Melnyk, C. W.

10.1101/2024.07.30.605771 — plant biology — Posted on 2024-07-30

289 The reducing end of cell wall oligosaccharides is critical for DAMP activity in Arabidopsis thaliana and can be exploited by oligosaccharide oxidases in the scavenging of phenolic radicals.

Giovannoni, M.; Scortica, A.; Scafati, V.; Piccirilli, E.; Sorio, D.; Benedetti, M.; Mattei, B.

10.1101/2024.07.30.605788 — plant biology — Posted on 2024-07-30

290 Genomic and transcriptomic profiles influence on brain morphology and their interactions with pain sensitivity

Pan, Y.; Zhang, Z.; Hao, X.; Huang, G.; Liang, Z.; Zhang, L.

10.1101/2024.07.30.605795 — bioinformatics — Posted on 2024-07-30

291 In silico PK predictions in Drug Discovery: Benchmarking of Strategies to Integrate Machine Learning with Empiric and Mechanistic PK modelling

Walter, M.; Aljayyoussi, G.; Gerner, B.; Rapp, H.; Tautermann, C. S.; Balazki, P.; Skalic, M.; Borghardt, J. M.; Humbeck, L.

10.1101/2024.07.30.605777 — bioinformatics — Posted on 2024-07-30

292 Single cell data enables dissecting cell types present in bulk transcriptome data

Wruck, W.; Adjaye, J.

10.1101/2024.07.30.605755 — bioinformatics — Posted on 2024-07-30

293 Sequence and structural analysis of adaptors of Toll-like receptor 4 sheds light on the evolutionary trajectory and functional emergence

Verma, S.; Sowdhamini, R.

10.1101/2024.07.30.605793 — bioinformatics — Posted on 2024-07-30

294 Anisotropic Articular Cartilage Biofabrication based on Decellularized Extracellular Matrix

Puiggali-Jou, A.; Hui, I.; Baldi, L.; Frischknecht, R.; Asadikorayem, M.; Janiak, J.; Chansoria, P.; McCabe, M. C.; Stoddart, M. J.; Hansen, K.; Christman, K. L.; Zenobi, M.

10.1101/2024.07.30.605411 — bioengineering — Posted on 2024-07-30

295 Intraperitoneal programming of tailored CAR macrophages via mRNA-LNP to boost cancer immunotherapy

Gu, K.; Liang, T.; Hu, L.; Zhao, Y.; Ying, W.; Zhang, M.; Chen, Y.; Liang, B.; Lin, X.; Zhang, Y.; Wu, H.; Wang, M.; Zhu, Y.; Wang, W.; Zhang, Y.; Zuo, C.; Du, Z.; Zhang, P.; Song, J.; Liu, X.; Xie, S.; Tan, W.

10.1101/2024.07.30.605730 — bioengineering — Posted on 2024-07-30

296 Chromosome-scale genome assembly of acerola (Malpighia emarginata DC.)

Shirasawa, K.; Harada, K.; Haramoto, N.; Aoki, H.; Kammera, S.; Yamamoto, M.; Nishizawa, Y.

10.1101/2024.07.30.605750 — genomics — Posted on 2024-07-30

297 Effects of selection for early dispersal on the ambrosia beetle Xyleborinus saxesenii and its fungal symbionts

Melet, A.; Biedermann, P.

10.1101/2024.07.30.605773 — evolutionary biology — Posted on 2024-07-30

298 Regulatory Subfunctionalization drives OXPHOS evolution in teleosts

Tsipourlianos, A.; Cardoso, J. C.; Angelakopoulos, R.; Kotoula, A.; Power, D. M.; Mamuris, Z.; Moutou, K. A.

10.1101/2024.07.30.605748 — evolutionary biology — Posted on 2024-07-30

299 patter: particle algorithms for animal tracking in R and Julia

Lavender, E.; Scheidegger, A.; Albert, C.; Biber, S. W.; Illian, J.; Thorburn, J.; Smout, S.; Moor, H.

10.1101/2024.07.30.605733 — ecology — Posted on 2024-07-30

300 A bioactive soluble recombinant mouse LIGHT promotes effective tumor immune cell infiltration delaying tumor growth

DEL RIO, M.-L.; Roncador, G.; Cubria, J.-C.; Schneider, P.; Rodriguez-Barbosa, J.-I.

10.1101/2024.07.30.605649 — immunology — Posted on 2024-07-30

301 Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection

Coulibaly, A. S. K.; Nozeran, L.; Thomann, C.; Alis, M.; Bassot, E.; Hassan, A.; Porte, R.; Belloy, M.; Blanchard, N.; Masson, F.

10.1101/2024.07.30.605547 — immunology — Posted on 2024-07-30

302 Understanding the development of neural abnormalities in adolescents with mental health problems: a longitudinal study

HOU, J.; van de Mortel, L. A.; Liu, W.; Liu, S.; Popma, A.; Smit, D. J. A.; van Wingen, G.

10.1101/2024.07.30.605786 — neuroscience — Posted on 2024-07-30

303 Identification and characterization of anti-epileptic compounds from Papaver somniferum using quantification techniques (GC-MS, FTIR), integrated network pharmacology, molecular docking, and molecular dynamics simulations

Shahzadi, K.; Rasool, D.; Irshad, F.; khalid, A.; ASLAM, S.; Nazir, A.

10.1101/2024.07.29.605558 — bioinformatics — Posted on 2024-07-30

304 Disruption of mitochondrial folate metabolism leads to mitochondrial DNA leakage and activation of apoptotic or inflammatory pathways

Hwang, S.; Baker, C.; Field, M. S.

10.1101/2024.07.30.605854 — biochemistry — Posted on 2024-07-30

305 Human-like APOBEC3 gene expression and anti-viral responses following replacement of mouse Apobec3 with the 7-gene human APOBEC3 locus

Kirkwood, N. K.; Prosser, H.; Yap, M. W.; Gibson, J.; Cook, R.; Reddin, I.; Stranger, A.; Howes, E.; Zainal, N.; Periyasamy, M.; Thomas, G. J.; Scott, J.; Bishop, K. N.; Ali, S.; Bradley, A.; Fenton, T. R.

10.1101/2024.07.30.605801 — cancer biology — Posted on 2024-07-30

306 ADAM17 regulates hepatic DNA damage repair and tumour formation

Reichert, M.; Halwachs, B.; Bolik, J.; Senftleben, A.; Krause, F.; Conrady, L.; Bauer, R.; Rachmilewitz, J.; Horejs-Hoeck, J.; Rose-John, S.; Schmidt-Arras, D.

10.1101/2024.07.30.605791 — cancer biology — Posted on 2024-07-30

307 diaPASEF analysis for HLA-I peptides enables quantification of common cancer neoantigens

Oliinyk, D.; Gurung, H.; Zhou, Z.; Leskoske, K.; Rose, C. M.; Klaeger, S.

10.1101/2024.07.30.605861 — cancer biology — Posted on 2024-07-30

308 Proteomics Landscape of Triple-Negative Apocrine Breast Carcinoma Reveals Molecular Mechanisms of Tumorigenesis and Characteristics of Chemo-insensitivity

Zhu, Y.; Long, M.; Shi, W.; He, T.; Xie, F.; Qian, A.; Liu, Y.; Hu, T.; Tang, S.

10.1101/2024.07.30.605782 — cancer biology — Posted on 2024-07-30

309 Fast and long-term super-resolution imaging of ER nano-structural dynamics in living cells using a neural network

Balakrishnan, A.; Rahm, J. V.; Wehrheim, M.; Kaminer, A.; Glogger, M.; Kessler, L. F.; Kaschube, M.; Barth, H.-D.; Heilemann, M.

10.1101/2024.07.30.605742 — biophysics — Posted on 2024-07-30

310 2,2-Di-Fluoro-Derivatives of Fucose Can Inhibit Cell Surface Fucosylation Without Causing Slow Transfer to Acceptors

Liu, Y.; Sweet, I.; Boons, G.-J.

10.1101/2024.07.30.605762 — biochemistry — Posted on 2024-07-30

311 Disruption of CAD oligomerization by pathogenic variants

del Cano-Ochoa, F.; Ramadane-Morchadi, L.; Eixeres, L.; Moreno-Morcillo, M.; Fernandez-Leiro, R.; Ramon-Maiques, S.

10.1101/2024.07.30.605799 — biochemistry — Posted on 2024-07-30

312 Distributed Collaboration for Data, Analysis Pipelines, and Results in Single-Cell Omics

Hutton, A.; Ai, L.; Meyer, J. G.

10.1101/2024.07.30.605714 — cell biology — Posted on 2024-07-30

313 Extracellular matrix integrity regulates GABAergic plasticity in the hippocampus

Jablonska, J.; Wiera, G.; Mozrzymas, J. W.

10.1101/2024.07.30.605739 — neuroscience — Posted on 2024-07-30

314 Cryo-EM structures of {rho}1 GABA(A) receptors with antagonist and agonist drugs

Fan, C.; Cowgill, J.; Howard, R. J.; Lindahl, E.

10.1101/2024.07.30.605774 — biophysics — Posted on 2024-07-30

315 Fast analysis of Spatial Transcriptomics (FaST): an ultra lightweight and fast pipeline for the analysis of high resolution spatial transcriptomics.

Fulci, V.

10.1101/2024.07.30.605511 — bioinformatics — Posted on 2024-07-30

316 Ca2+-driven PDIA6 phase separation to ensure proinsulin quality control

Lee, Y.-H.; Saio, T.; Watabe, M.; Matsusaki, M.; Kanemura, S.; Lin, Y.; Mannen, T.; Kuramochi, T.; Iuchi, K.; Tajiri, M.; Suzuki, K.; Li, Y.; Heo, Y.; Kamada, Y.; Arai, K.; Hashimoto, M.; Ninagawa, S.; Hattori, Y.; Kumeta, H.; Takeuchi, A.; Abe, H.; Mori, E.; Muraoka, T.; Okiyoneda, T.; Akashi, S.; Vendruscolo, M.; Inaba, K.; Okumura, M.

10.1101/2024.07.30.605722 — biochemistry — Posted on 2024-07-30

317 The origin of septin ring size control in budding yeast

Kukhtevich, I.; Persson, S.; Padovani, F.; Schneider, R.; Cvijovic, M.; Schmoller, K. M.

10.1101/2024.07.30.605628 — cell biology — Posted on 2024-07-30

318 S. cerevisiae serves as keystone species for spoilage resistance in experimental synthetic wine yeast communities

Leale, A. M.; Pourcelot, E.; Guezenec, S.; Sicard, D.; Nidelet, T.

10.1101/2024.07.04.602080 — ecology — Posted on 2024-07-30

319 One to rule them all? Assessing the performance of sustainable forest management indicators against multitaxonomic data for biodiversity conservation

Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Jung, K.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Wohlwend, M.; Burrascano, S.

10.1101/2024.02.12.579875 — ecology — Posted on 2024-07-30

320 Atypical soluble guanylyl cyclases control brain size in Drosophila

Prieto, D.; Egger, B.; Cantera, R.

10.1101/2024.07.17.603894 — developmental biology — Posted on 2024-07-30

321 Epsins oversee smooth muscle cell reprogramming by influencing master regulators KLF4 and OCT4.

Wang, B.; Cui, K.; Zhu, B.; Dong, Y.; Wang, D.; Singh, B.; Wu, H.; Li, K.; Eisa-Beygi, S.; Sun, Y.; Wong, S.; Cowan, D. B.; Chen, Y.; Du, M.; Chen, H.

10.1101/2024.01.08.574714 — cell biology — Posted on 2024-07-30

322 Glucocorticoids desensitize CRH neurons to norepinephrine via rapid nitrosylation-dependent regulation of α1 adrenoreceptor trafficking

Weiss, G. L.; Harrison, L. M.; Jiang, Z.; Nielsen, A. M.; Feygin, M. S.; Nguyen, S.; Tirrell, P. S.; Tasker, J. G.

10.1101/2024.07.29.605704 — neuroscience — Posted on 2024-07-30

323 Low-side and multitone suppression in the base of the gerbil cochlea

Strimbu, C. E.; Olson, E. S.

10.1101/2024.07.29.605696 — neuroscience — Posted on 2024-07-30

324 Rapid eye and hand responses in an interception task are differentially modulated by context-dependent predictability

Fooken, J.; Balalaie, P.; Park, K.; Flanagan, J. R.; Scott, S. H.

10.1101/2024.07.11.603058 — neuroscience — Posted on 2024-07-30

325 Evolution and diversification of the momilactone biosynthetic gene cluster in the genus Oryza

Priego Cubero, S.; Toyomasu, T.; Gigl, M.; Liu, Y.; Hasegawa, Y.; Nojiri, H.; Dawid, C.; Okada, K.; Becker, C.

10.1101/2024.01.11.572147 — plant biology — Posted on 2024-07-30

326 Efficient integration of multiple spatial transcriptomics data for 3D domain detection, matching, and alignment with stMSA

Shu, H.; Chen, J.; Hu, J.; Wang, Y.; Peng, J.; Shang, X.; Wang, T.

10.1101/2024.07.29.605604 — bioinformatics — Posted on 2024-07-30

327 The VanS sensor histidine kinase from type-B VRE recognizes vancomycin directly

Maciunas, L. J.; Rotsides, P.; D'Lauro, E. J.; Brady, S.; Beld, J.; Loll, P. J.

10.1101/2023.07.09.548278 — biochemistry — Posted on 2024-07-30

328 Mechanical problem solving in mice

Boon, M. N.; Andresen, N.; Traverso, S.; Meier, S.; Schuessler, F.; Hellwich, O.; Lewejohann, L.; Thöne-Reineke, C.; Sprekeler, H.; Hohlbaum, K.

10.1101/2024.07.29.605658 — animal behavior and cognition — Posted on 2024-07-30

329 Novel Approach for Refractive Index Matching in Calcified Tissues

Laudier, D.; Mora-Antionette, M.; Garcia-Ortiz, A.; Lewis, K. J.

10.1101/2024.07.23.604611 — cell biology — Posted on 2024-07-30

330 Structures of H2A.Z-associated human chromatin remodelers SRCAP and TIP60 reveal divergent mechanisms of chromatin engagement

Park, G.; Patel, A. B.; Wu, C.; Louder, R. K.

10.1101/2024.07.30.605802 — molecular biology — Posted on 2024-07-30

331 Gustatory Thalamic Neurons Mediate Aversive Behaviors

Cao, F.; Park, S.; Pauli, J. L.; Seo, E. Y.; Palmiter, R. D.

10.1101/2024.07.29.605702 — neuroscience — Posted on 2024-07-30

332 Exploring potential targets for quercetin treatment of colorectal cancer through network pharmacology and molecular docking technology

Qian, Y.; Wang, Z.; Ji, J.; Fu, W.

10.1101/2024.07.29.605708 — pharmacology and toxicology — Posted on 2024-07-30

333 CaLMPhosKAN: Prediction of General Phosphorylation Sites in Proteins via Fusion of Codon Aware Embeddings with Amino Acid Aware Embeddings and Wavelet-based Kolmogorov Arnold Network

Pratyush, P.; Carrier, C.; Pokharel, S.; Ismail, H. D.; Chaudhari, M.; KC, D. B.

10.1101/2024.07.30.605530 — bioinformatics — Posted on 2024-07-30

334 Evolution of the RNA alternative decay cis element into a high-affinity target for the immunomodulatory protein Roquin

Tants, J.-N.; Friedrich, K.; Neumann, J.; Schlundt, A.

10.1101/2024.07.30.605734 — biochemistry — Posted on 2024-07-30

335 Harnessing genome prediction in Brassica napus through a nested association mapping population

Perumal, S.; Higgins, E.; Sra, S.; Khedikar, Y.; Moore, J.; Chaudhary, R.; Haile, T.; Koh, C. S.; Vail, S.; Robinson, S. J.; Horner, K. N.; Hope, B.; Klein-Gebbinck, H.; Herrmann, D.; Navabi, Z.-K.; Sharpe, A. G.; Parkin, I. A. P.

10.1101/2024.07.29.604859 — genomics — Posted on 2024-07-30

336 Genome structural variants shape adaptive success of an invasive urban malaria vector Anopheles stephensi

Samano, A.; Chakraborty, M.; Liao, Y.; Ishtiaq, F.; Kumar, N.

10.1101/2024.07.29.605641 — evolutionary biology — Posted on 2024-07-30

337 Change in functional trait diversity mediates the effects of nutrient addition on grassland stability

Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, S.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.

10.1101/2022.09.16.508233 — ecology — Posted on 2024-07-30

338 Deletion of Setd7 protects against cardiac hypertrophy via inhibiting lipid oxidation

Su, H.; Wang, J.; Zhang, Y.; Xu, J.; Liu, J.; Li, Y.; Xiao, C.; Wang, C.; Chang, J.; Liu, X.

10.1101/2024.07.29.605718 — molecular biology — Posted on 2024-07-30

339 Nutrition induced changes in the microbiota can cause dysbiosis and disease development

Lachnit, T.; Ulrich, L.; Willmer, F. M.; Hasenbein, T.; Steiner, L. X.; Wolters, M.; Herbst, E. M.; Deines, P.

10.1101/2024.07.29.605727 — microbiology — Posted on 2024-07-30

340 Cell binding, uptake and infection of influenza A virus using recombinant antibody-based receptors.

Adu, O. F.; Sempere Borau, M.; Frueh, S. P.; Karakus, U.; Weichert, W.; Wasik, B. R.; Stertz, S.; Parrish, C. R.

10.1101/2024.07.29.605726 — microbiology — Posted on 2024-07-30

341 An IL-12 mRNA-LNP adjuvant enhances mRNA-LNP vaccine induced CD8+ T cell responses

Aunins, E. A.; Phan, A. T.; Alameh, M.-G.; Cruz-Morales, E.; Christian, D. A.; Bunkofske, M. E.; Dwivedi, G.; Weissman, D.; Hunter, C.

10.1101/2024.07.29.605626 — immunology — Posted on 2024-07-30

342 Visual to default network pathways: A double dissociation between semantic and spatial cognition

Gonzalez Alam, T. R.; Krieger-Redwood, K.; Varga, D.; Gao, Z.; Horner, A. R.; Hartley, T.; Thiebaut de Schotten, M.; Sliwinska, M. W.; Pitcher, D.; Margulies, D. S.; Smallwood, J.; Jefferies, E.

10.1101/2023.11.28.568861 — neuroscience — Posted on 2024-07-30

343 Model of a striatal circuit exploring biological mechanisms underlying decision-making during normal and disordered states

Beck, D. W.; Heaton, C. N.; Davila, L. D.; Rakocevic, L. I.; Drammis, S. M.; Tyulmankov, D.; Vara, P.; Giri, A.; Umashankar Beck, S.; Zhang, Q.; Pokojovy, M.; Negishi, K.; Batson, S. A.; Salcido, A. A.; Reyes, N. F.; Macias, A. Y.; Ibanez-Alcala, R. J.; Hossain, S. B.; Waller, G. L.; O'Dell, L. E.; Moschak, T. M.; Goosens, K. A.; Friedman, A.

10.1101/2024.07.29.605535 — neuroscience — Posted on 2024-07-30

344 Low-side and multitone suppression in the base of the gerbil cochlea

Strimbu, C. E.; Olson, E. S. E.

10.1101/2024.07.29.605696 — neuroscience — Posted on 2024-07-30

345 Integrative, high-resolution analysis of single cells across experimental conditions with PARAFAC2

Ramirez, A.; Orcutt-Jahns, B. T.; Pascoe, S.; Abraham, A.; Remigio, B.; Thomas, N.; Meyer, A. S.

10.1101/2024.07.29.605698 — systems biology — Posted on 2024-07-30

346 Deciphering the transcriptional regulatory network of Yarrowia lipolytica using machine learning

Kerssemakers, A. A. J.; Krishnan, J.; Rychel, K.; Zielinski, D. C.; Palsson, B.; Sudarsan, S.

10.1101/2024.07.29.605545 — systems biology — Posted on 2024-07-30

347 Unraveling the Web of Life: Incomplete lineage sorting and hybridization as primary mechanisms over polyploidization in the evolutionary dynamics of pear species

Jin, Z.; Lin, X.; Ma, D.; Hodel, R. G. J.; Zhao, L.; Ren, C.; Duan, L.; Xu, C.; Wu, J.; Liu, B.

10.1101/2024.07.29.605463 — systems biology — Posted on 2024-07-30

348 Time-resolved tracking of cellulose biosynthesis and microfibril network assembly during cell wall regeneration in live Arabidopsis protoplasts

Huh, H.; Jayachandran, D.; Sun, J.; Irfan, M.; Lam, E.; Chundawat, S. P. S.; Lee, S.-H.

10.1101/2024.07.29.605709 — plant biology — Posted on 2024-07-30

349 Efficient in situ epitope tagging of rice genes by nuclease-mediated prime editing

Li, X.; Zhang, S.; Wang, C.; Ren, B.; Yan, F.; Li, S.; Spetz, C.; Huang, J.; Zhou, X.; Zhou, H.

10.1101/2024.07.29.605657 — plant biology — Posted on 2024-07-30

350 A new tuna specimen (Genus Auxis) from the Duho Formation (middle Miocene) of South Korea

Suh, D.; Kim, S.-H.; Nam, G.-S.

10.1101/2024.07.29.605724 — paleontology — Posted on 2024-07-30

351 Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression

Onate, M. K.; Oon, C.; Bhattacharyya, S.; Low, V.; Chen, C.; Zhao, X.; Yan, Z.; Hang, Y.; Kim, S. K.; Xia, Z.; Sherman, M. H.

10.1101/2024.07.29.605485 — cancer biology — Posted on 2024-07-30

352 Amyloid peptide - synthetic polymer blends with enhanced mechanical and biological properties

Wang, X.; Mondal, M.; Jankoski, P. E.; Kemp, L. K.; Clemons, T. D.; Rangachari, V.; Morgan, S. E.

10.1101/2024.07.29.605712 — biophysics — Posted on 2024-07-30

353 Sequence of the SARS-CoV-2 spike transmembrane domain makes it inherently dynamic

Lall, S.; Balaram, P.; Mathew, M. K.; Gosavi, S.

10.1101/2021.06.07.447334 — biophysics — Posted on 2024-07-30

354 On branch lengths assignment methods for trees with fixed topology and related biological applications

Wei, W.; Koslicki, D.

10.1101/2024.07.29.605688 — bioinformatics — Posted on 2024-07-30

355 PCA-based spatial domain identification with state-of-the-art performance

Schaub, D. P.; Yousefi, B.; Kaiser, N.; Khatri, R.; Puelles, V. G.; Krebs, C. F.; Panzer, U.; Bonn, S.

10.1101/2024.07.29.605550 — bioinformatics — Posted on 2024-07-30

356 Accelerated Simulation of Multi-Electrode Arrays Using Sparse and Low-Rank Matrix Techniques

Jensen, N.; Chen, Z. C.; Kochnev Goldstein, A.; Palanker, D.

10.1101/2024.07.29.605687 — bioengineering — Posted on 2024-07-30

357 Calcium phosphate nanoclusters modify periodontium remodeling and minimize orthodontic relapse

Cuylear, D. L.; Fu, M. L.; Chau, J. C.; Kharbikar, B.; Kazakia, G.; Jheon, A.; Habelitz, S.; Kapila, S. D.; Desai, T. A.

10.1101/2024.07.29.605671 — bioengineering — Posted on 2024-07-30

358 Methods for detecting 'missing' dimensions in genetic covariance matrices

Dochtermann, N. A.

10.1101/2024.07.29.605681 — evolutionary biology — Posted on 2024-07-30

359 Topological mixing and irreversibility in animal chromosome evolution

Schultz, D. T.; Blümel, A.; Destanovic, D.; Sarigol, F.; Simakov, O.

10.1101/2024.07.29.605683 — evolutionary biology — Posted on 2024-07-30

360 Eco-evolutionary dynamics of temperate phages in periodic environments

Goel, T.; Beckett, S. J.; Weitz, J. S.

10.1101/2024.07.29.604806 — ecology — Posted on 2024-07-30

361 Appendage regeneration requires IMPDH2 and creates a sensitized environment for enzyme filament formation

McCartney, M. E.; Wheeler, G. M.; O'Neill, A. G.; Patel, J. H.; Litt, Z. R.; Calise, S. J.; Kollman, J. M.; Wills, A. E.

10.1101/2024.07.29.605679 — developmental biology — Posted on 2024-07-30

362 Long-lived chondroprogenitors are generated by fetal-limb Gli1+ cells and are replenished upon mosaic cell-cycle arrest in the cartilage

Qu, X.; Razmara, E.; H'ng, C. H.; Vinu, K. K.; Martelotto, L. G.; Zethoven, M.; Rossello, F. J.; Johnstone, R. W.; Amarasinghe, S. L.; Powell, D. R.; Rosello-Diez, A.

10.1101/2024.07.29.603524 — developmental biology — Posted on 2024-07-30

363 The Contribution of the membrane-bound complement regulatory proteins CD46 and CD55 in phases of acute lymphocytic leukemia (ALL) and acute myelogenous leukemia (AML)

Saeed, L. O.; Ammar, P. A.; AbdElaziz, H.; Abou-Aisha, K.; Farag, N. S.; El-Azizi, M.

10.1101/2024.07.29.601818 — immunology — Posted on 2024-07-30

364 Templating of Monomeric Alpha-Synuclein Induces Inflammation and SNpc Dopamine Neuron Death in a Genetic Mouse Model of Synucleinopathy.

Byrne, M. D.; Petramfar, P.; Smeyne, R. J.

10.1101/2024.07.29.605647 — neuroscience — Posted on 2024-07-30

365 Effects of two different compounds on seizure suppression using the zebrafish PTZ-seizure model

Fernandez, J. A. A.; de Moura, T. C.; Vila, S. F.; Gaytan, J. A. R.; Lopez-Diaz, I.; Learte-Aymami, S.; Vazquez, M. E.; Mayan, M. D.; Sanchez, L.; Maurer-Morelli, C. V.

10.1101/2024.07.29.605666 — neuroscience — Posted on 2024-07-30

366 Pervasive neurovascular dysfunction in the ventromedial prefrontal cortex of female depressed suicides with a history of childhood abuse

Wakid, M.; Almeida, D.; Denniston, R.; Chawla, A.; Aouabed, Z.; Davoli, M. A.; Rahimian, R.; Ellerbeck, K.; Yerko, V.; Leonova-Erko, E.; Turecki, G.; Mechawar, N.

10.1101/2024.07.29.605502 — neuroscience — Posted on 2024-07-30

367 Shifts in neural tuning systematically alter sensorimotor learning ability

Hayashi, T.; Takiyama, K.; Smith, M. A.; Nozaki, D.

10.1101/2024.07.29.605715 — neuroscience — Posted on 2024-07-30

368 Age-related myelin deficits in the auditory brain stem contribute to cocktail party-deficits

Poleg, S.; Li, B.-Z.; Ridenour, M.; Hughes, E. G.; Tollin, D.; Klug, A.

10.1101/2024.07.29.605710 — neuroscience — Posted on 2024-07-30

369 Ototoxicity-related Changes in GABA Immunolabeling Within the Rat Inferior Colliculus

Holt, A. G.; Griffith, R. D.; Lee, S. D.; Asako, M.; Buras, E.; Yalcinoglu, S.; Altschuler, R. A.

10.1101/2024.07.29.603150 — neuroscience — Posted on 2024-07-30

370 A modular system to label endogenous presynaptic proteins using split fluorophores in C. elegans

Kurashina, M.; Snow, A. W.; Mizumoto, K.

10.1101/2024.07.29.605690 — neuroscience — Posted on 2024-07-30

371 Pharyngeal neuronal mechanisms governing sour taste perception in Drosophila melanogaster

Shrestha, B.; Sang, J.; Rimal, S.; Lee, Y.

10.1101/2024.07.30.605738 — neuroscience — Posted on 2024-07-30

372 Contrast gain control is a reparameterization of a population response curve

Tring, E.; Moosavi, S. A.; Dipoppa, M.; Ringach, D.

10.1101/2024.07.29.605608 — neuroscience — Posted on 2024-07-30

373 K-mer Genome-wide Association Study for Anthracnose and BCMV Resistance in the Andean Diversity Panel

Wiersma, A.; Hamilton, J. P.; Vaillanoucrt, B.; Brose, J.; Awale, H. E.; Wright, E. M.; Kelly, J. D.; Buell, C. R.

10.1101/2024.07.29.605481 — plant biology — Posted on 2024-07-30

374 Remote organ cancer adversely alters renal function and induces kidney injury, inflammation, and fibrosis.

Hammouri, D.; Orwick, A.; Doll, M.; Sanchez Vega, D.; Shah, P. P.; Clarke, C. J.; Clem, B.; Beverly, L. J.; Siskind, L. J.

10.1101/2024.07.29.605635 — physiology — Posted on 2024-07-30

375 Genetic Manipulation of Caveolin-1 in the Mouse Model of Marfan Syndrome Associated Aortic Root Aneurysm: Effects on Endothelial and Smooth Muscle Function

Curry-Koski, T.; Gusek, B.; Potter, R. M.; Jones, T. B.; Dickman, R.; Johnson, N.; Vallejo-Elias, J.; Esfandiarei, M.

10.1101/2024.07.29.605631 — physiology — Posted on 2024-07-30

376 Subtypes and proliferation patterns of small intestine neuroendocrine tumors revealed by single cell RNA sequencing

Somech, E.; Halder, D.; Spitzer, A.; Barbolin, C.; Tyler, M.; Halperin, R.; Biton, M.; Tirosh, A.; Tirosh, I.

10.1101/2024.07.29.605642 — cancer biology — Posted on 2024-07-30

377 Senescent fibroblasts in the tumor stroma rewire lung cancer metabolism and plasticity

Lee, J.; Nabora, S. R.; Woo, S.-H.; Goel, S.; Stratton, F.; Kuang, C.; Mansfield, A.; LaFave, L.; Peng, T.

10.1101/2024.07.29.605645 — cancer biology — Posted on 2024-07-30

378 A structural and mechanistic model for BSEP dysfunction in PFIC2 cholestatic disease

Moore, J. M.; Gruget, C.; Reddy, B.

10.1101/2024.07.29.605648 — biophysics — Posted on 2024-07-30

379 Variability in Individual Native Fibrin Fiber Mechanics

Helms, C. C.

10.1101/2024.07.29.605650 — biophysics — Posted on 2024-07-30

380 Collective flow of circadian clock information in honeybee colonies

Mellert, J.; Kłos, W.; Dormagen, D. M.; Wild, B.; Zachariae, A.; Smith, M. L.; Galizia, C. G.; Landgraf, T.

10.1101/2024.07.29.605620 — animal behavior and cognition — Posted on 2024-07-30

381 Genetic diversity analysis of main agronomic traits and ISSR markers in 35 ornamental rape germplasm resources

Xia, M.; Chen, M.; Dong, X.; Chen, M.; Chen, J.; Wang, H.; Dong, Y.; Zeng, C.; Dai, X.; Meizhu Chen,Xiaoxiao Dong, Jingdong Chen, Miao Cheng, Heping Wan, Yuanhuo Dong, Changli Zeng and Xig,

10.1101/2024.07.29.605676 — genetics — Posted on 2024-07-30

382 Cathelicidin antimicrobial peptides mediate immune protection of marsupial neonates

Park, J.; Ke, W.; Kaage, A.; Feigin, C. Y.; Pritykin, Y.; Donia, M. S.; Mallarino, R.

10.1101/2024.07.29.605640 — evolutionary biology — Posted on 2024-07-30

383 CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss

Wu, S.; Lin, L.; Hu, Q.; Yao, X.; Wang, H.; Liu, S.; Liu, Q.; Xi, Y.; Lin, Y.; Gong, J.; Hu, R.; Zhan, W.; Luo, Y.; He, G.; Liu, Z.; Xiong, W.; Wang, Q.; Xu, Z.; Bai, F.; Lu, Q.

10.1101/2024.07.24.604958 — molecular biology — Posted on 2024-07-30

384 On the mode of anti-C. albicans activity of a bis(benzoxaborole) analogue of Tavaborole

Gadakh, S.; Szczepinska, T.; Potoczna, M.; Sakutayama, S. O.; Podlasz, P.; Rogalska, M.; Kaczorowska, E.; Adamczyk-Wozniak, A.; Staniszewska, M.

10.1101/2024.07.29.605614 — microbiology — Posted on 2024-07-30

385 Understanding human amygdala function with artificial neural networks

Kragel, P. A.; Jang, G.

10.1101/2024.07.29.605621 — neuroscience — Posted on 2024-07-30

386 Effects of ketamine on GABAergic and glutamatergic activity in the mPFC: biphasic recruitment of GABA function in antidepressant-like responses

V Fogaca, M.; Daher, F.; Picciotto, M.

10.1101/2024.07.29.605610 — neuroscience — Posted on 2024-07-30

387 Three Dimensional Multiscalar Neurovascular Nephron Connectivity Map of the Human Kidney Across the Lifespan

McLaughlin, L.; Zhang, B.; Sharma, S.; Knoten, A. L.; Kaushal, M.; Purkerson, J. M.; Huyck, H.; Pryhuber, G. S.; Gaut, J. P.; Jain, S.

10.1101/2024.07.29.605633 — neuroscience — Posted on 2024-07-30

388 Chemical genetics reveals cross-activation of plant developmental signaling by the immune peptide-receptor pathway

Herrmann, A.; Sepuru, K. M.; Endo, H.; Nakagawa, A.; Kusao, S.; Bai, P.; Ziadi, A.; Kato, H.; Sato, A.; Liu, J.; Shan, L.; Kimura, S.; Itami, K.; Uchida, N.; Hagihara, S.; Torii, K. U.

10.1101/2024.07.29.605519 — plant biology — Posted on 2024-07-30

389 Longitudinal Decline of Exercise Capacity in Male and Female Mice

Pajski, M. L.; Maroto, R.; Byrd, C.; Graber, T. G.

10.1101/2024.07.29.605646 — physiology — Posted on 2024-07-30

390 A trimeric USP11/USP7/TCEAL1 complex stabilizes RNAPII during early transcription to sustain oncogenic gene expression

Dehmer, M.; Gallant, P.; Herold, S.; Cossa, G.; Conte, F.; Koster, J.; Sauer, F.; Schuelein-Voelk, C.; Ade, C. P.; Vidal, R.; Kisker, C.; Versteeg, R.; Beli, P.; Vos, S.; Eilers, M.; Buechel, G.

10.1101/2024.07.29.605622 — cancer biology — Posted on 2024-07-30

391 Resolving the Structure of a Guanine Quadruplex in TMPRSS2 Messenger RNA by Circular Dichroism and Molecular Modeling

D'Anna, L.; Froux, A.; Rainot, A.; Spinello, A.; Perricone, U.; Barbault, F.; Grandemange, S.; Barone, G.; Terenzi, A.; Monari, A.

10.1101/2024.07.29.605618 — biophysics — Posted on 2024-07-30

392 Ranking Single Fluorescent Protein Based Calcium Biosensor Performance by Molecular Dynamics Simulations

ATILGAN, C.; Berksoz, M.

10.1101/2024.07.29.605619 — biophysics — Posted on 2024-07-30

393 Explicit description of viral capsid subunit shapes by unfolding dihedrons

Toyooka, R.; Nishimoto, S.; Tendo, T.; Horiyama, T.; Tachi, T.; Matsunaga, Y.

10.1101/2024.07.29.605617 — biophysics — Posted on 2024-07-30

394 Three-Dimensional Quantitative Structure-Activity Relationships and Molecular Dynamic Simulations Studies to Discover Aurora Kinase-B Inhibitors

Selvam, A. A. A.; Senthamaraikannan, K.

10.1101/2024.07.29.605534 — bioinformatics — Posted on 2024-07-30

395 Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus

Jönsson, M.; Sigrist, R.; Gren, T.; Semenov Petrov, M.; Marcussen, N.; Svetlova, A.; Charusanti, P.; Gockel, P.; Palsson, B. O.; Yang, L.; Özdemir, E.

10.1101/2024.01.09.574332 — genomics — Posted on 2024-07-30

396 Impact of preanalytical factors on liquid biopsy in the canine cancer model

Megquier, K.; Husted, C.; Rhoades, J.; White, M. E.; Genereux, D. P.; Chen, F. L.; Xiong, K.; Kwon, E.; Swofford, R.; Painter, C.; Adalsteinsson, V.; London, C. A.; Gardner, H. L.; Karlsson, E. K.

10.1101/2024.07.29.605605 — genomics — Posted on 2024-07-30

397 Dissecting the Genetic Basis of Superior Traits in Thermosensitive Genic Male Sterile Line 1892S Through Genome-Wide Analysis

Zhang, W.; Zhang, D.

10.1101/2024.07.29.605629 — genomics — Posted on 2024-07-30

398 Evolution of irreversible differentiation under stage-dependent cell differentiation

Gao, Y.; Zapien-Campos, R.; Pichugin, Y.; Traulsen, A.

10.1101/2023.05.04.539351 — evolutionary biology — Posted on 2024-07-30

399 Evolutionary Insights from the Mitochondrial Genome of Oikopleura dioica: Sequencing Challenges, RNA Editing, Gene Transfers to the Nucleus, and tRNA Loss

Klirs, Y.; Novosolov, M.; Gissi, C.; Garic, R.; Pupko, T.; Huchon, D.

10.1101/2024.05.09.593300 — evolutionary biology — Posted on 2024-07-30

400 Sepsis-induced NET formation requires MYD88 but is independent of GSDMD and PAD4

Renne, T.; Englert, H.; Rangaswamy, C.; Divivier, M.; Göbel, J.; Hermans-Borgmeyer, I.; Borgmeyer, U.; Mowen, K. A.; Beerens, M.; Frye, M.; Mailer, R. K.; Gelderblom, M.; Stavrou, E.; Preston, R. J.; Schneider, S. W.; Fuchs, T. A.

10.1101/2024.07.29.605563 — immunology — Posted on 2024-07-30

401 Limiting mitochondrial-derived ATP transfer to the cytosol enhances T-cell activation

Yosef, O.; Cohen-Daniel, L.; Shamriz, O.; Bar-On, Z.; Saragovi, A.; Abramovich, I.; Agranovich, B.; Lutz, V.; Tam, J.; Permyakova, A.; Gottlieb, E.; Huber, M.; Berger, M.

10.1101/2024.04.21.590436 — immunology — Posted on 2024-07-30

402 Learning and modality independent time cells tile stimulus and post-stimulus period.

Bhattacharjee, S.; Nambisan, H.; Bhalla, U. S.

10.1101/2024.07.28.605458 — neuroscience — Posted on 2024-07-30

403 Calcium-independent lipid release from astrocytes modulates neuronal excitability

Wang, F.; Bradshaw, H. B.; Jablonska, B.; Pena, S. E.; Chittaranjan, S.; Xavier, J.; Gong, S.; Li, B.; Chandler-Militello, D.; Bekar, L. K.; Smith, N. A.

10.1101/2020.01.12.903393 — neuroscience — Posted on 2024-07-30

404 Structural diversity of mitochondria in the neuromuscular system across development

Bae, J. A.; Choi, M.-k.; Ahn, S.; Ko, G.; Choe, D. T.; Yim, H.; Nguyen, K. C. Q.; Kim, J. S.; Hall, D. H.; Lee, J.

10.1101/2024.07.19.604219 — neuroscience — Posted on 2024-07-30

405 DNA damage response signatures are associated with frontline chemotherapy response and routes of tumor evolution in extensive stage small cell lung cancer

Morris, B. B.; Heeke, S.; Xi, Y.; Diao, L.; Wang, Q.; Rocha, P.; Arriola, E.; Lee, M. C.; Tyson, D. R.; Concannon, K.; Ramkumar, K.; Stewart, C. A.; Cardnell, R. J.; Wang, R.; Quaranta, V.; Wang, J.; Heymach, J. V.; Nabet, B. Y.; Shames, D. S.; Gay, C. M.; Byers, L. A.

10.1101/2024.07.29.605595 — cancer biology — Posted on 2024-07-30

406 Long-range somatic structural variation calling from matched tumor-normal co-assembly graphs

Le, M. K.; Qin, Q.; Li, H.

10.1101/2024.07.29.605160 — bioinformatics — Posted on 2024-07-30

407 Using flux theory in dynamic omics data sets to identify differentially changing signals using DPoP

Edwards, H.; Zavorskas, J.; Huso, W.; Doan, A. G.; Silbiger, C.; Harris, S.; Srivastava, R.; Marten, M. R.

10.1101/2024.07.29.605590 — bioinformatics — Posted on 2024-07-30

408 Paternal genome elimination creates contrasting evolutionary trajectories in male and female citrus mealybugs

Mongue, A. J.; Woodman, T.; Marshall, H.; Garber, A. J.; Franco, J. C.; McCutcheon, J. P.; Ross, L.

10.1101/2024.07.28.604693 — evolutionary biology — Posted on 2024-07-30

409 A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant

Lawrence, G. J.

10.1101/2024.07.01.601607 — molecular biology — Posted on 2024-07-30

410 Molecular architecture of the altered cortical complexity in autism

Mamat, M.; Chen, Y.; Shen, W.; Li, L.

10.1101/2024.07.28.605533 — neuroscience — Posted on 2024-07-30

411 Latent mitotic vulnerability of AML cells induced by therapeutic agents

Niikura, R.; Yabushita, T.; Yamamoto, S.; Suzuki, H.; Fukuyama, M.; Hata, S.; Goyama, S.; Kitamura, T.; Chinen, T.; Kitagawa, D.

10.1101/2024.06.27.600939 — cancer biology — Posted on 2024-07-30

412 HELP: A computational framework for labelling and predicting human common and context-specific essential genes

Granata, I.; Maddalena, L.; Manzo, M.; Guarracino, M. R.; Giordano, M.

10.1101/2024.04.16.589691 — bioinformatics — Posted on 2024-07-30

413 TissueViewer: A Web-Based Multiplexed Image Viewer

van IJzendoorn, D. G. P.; Matusiak, M.; West, R. B.; van de Rijn, M.

10.1101/2024.06.21.600100 — bioinformatics — Posted on 2024-07-30

414 Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design

Tomilova, Y. E.; Russkikh, N. E.; Yi, I. M.; Shaburova, E. V.; Tomilov, V. N.; Pyrinova, G. B.; Brezhneva, S. O.; Tikhonyuk, O. S.; Gololobova, N. S.; Popichenko, D. V.; Arkhipov, M. O.; Bryzgalov, L. O.; Brenner, E. V.; Artyukh, A. A.; Shtokalo, D. N.; Antonets, D. V.; Ivanov, M. K.

10.1101/2024.07.24.604875 — bioengineering — Posted on 2024-07-30

415 The porphyran degradation system is complete, phylogenetically and geographically diverse across the gut microbiota of East Asian populations

Segurel, L.; Ulaganathan, T. S.; Mathieu, S.; Loiodice, M.; Poulet, L.; Drouillard, S.; Cygler, M.; Helbert, W.

10.1101/2023.03.30.534863 — biochemistry — Posted on 2024-07-30

416 Modeling Symbiont Dynamics and Coral Regulation under Changing Temperatures

Cavailles, J.; Kuzmics, C.; Grube, M.

10.1101/2024.04.10.588659 — ecology — Posted on 2024-07-30

417 Functional networks of inhibitory neurons orchestrate synchrony in the hippocampus

Bocchio, M.; Vorobyev, A.; Sadeh, S.; Brustlein, S.; Dard, R.; Reichinnek, S.; EMILIANI, V.; Baude, A.; Clopath, C.; Cossart, R.

10.1101/2023.09.18.558335 — neuroscience — Posted on 2024-07-30

418 Temporal modulation of tactile perception during balance control

Wachsmann, F. D.; Fiehler, K.; Voudouris, D.

10.1101/2023.11.02.565260 — neuroscience — Posted on 2024-07-30

419 Nuclear Argonaute protein NRDE-3 switches small RNA binding partners during embryogenesis coincident with the formation of SIMR granules

Chen, S.; Phillips, C. M.

10.1101/2024.07.29.605686 — cell biology — Posted on 2024-07-30

420 The Unkempt RNA binding protein reveals a local translation program in centriole overduplication

Martinez, A.; Stemm-Wolf, A. J.; Sheridan, R. M.; Taliaferro, M.; Pearson, C. G.

10.1101/2024.07.29.605660 — cell biology — Posted on 2024-07-30

421 Efficient generation of CAR NK cells from human umbilical cord blood CD34+ stem and progenitors for democratizing affordable immunotherapy

Li, J.; Wang, Y.; Zheng, X.; Lin, Y.; Weng, Q.; Liu, X.; Geng, Y.; Wu, H.; Liu, L.; Peng, H.; Wu, B.; Huang, D.; Xia, C.; Wang, T.; Zhang, M.; Du, X.; Zeng, H.; Dong, F.; Zhang, Y.; Zhu, X.; Hu, F.; Wang, J.

10.1101/2024.07.30.605741 — cell biology — Posted on 2024-07-30

422 Aneuploidy-induced proteostasis disruption impairsmitochondrial functions and mediates aggregation ofmitochondrial precursor proteins through SQSTM1/p62

Amponsah, P. S.; Boekenkamp, J.-E.; Lenhard, S.; Behrends, C.; Herrmann, J.; Raeschle, M.; Storchova, Z.

10.1101/2024.07.29.605607 — cell biology — Posted on 2024-07-30

423 Formation of stress granules and non-canonical survival responses in arsenite-exposed cells.

Hirano, S.; Udagawa, O.; Kanno, S.

10.1101/2024.07.29.605725 — cell biology — Posted on 2024-07-30

424 Human immunodeficiency virus-1 induces host genomic R-loop and preferentially integrates its genome near the R-loop regions

Park, K.; Lee, D.; Jeong, J.; Lee, S.; Kim, S.; Ahn, K.

10.1101/2024.03.06.583715 — molecular biology — Posted on 2024-07-30

425 Perturbation-response analysis of in silico metabolic dynamics in nonlinear regime: Hard-coded responsiveness in the cofactors and network sparsity

Himeoka, Y.; Furusawa, C.

10.1101/2023.10.18.562862 — systems biology — Posted on 2024-07-30

426 Biregional division angles generate sharp apex and concave joints in leaves

Wang, Z.; Inoue, Y.; Mochizuki, A.; Tsukaya, H.

10.1101/2024.07.28.605531 — plant biology — Posted on 2024-07-30

427 Multiscale mechanics drive functional maturation of the vertebrate heart

Andrews, T. G.; Cornwall Scoones, J.; Ramel, M.-C.; Gupta, K.; Briscoe, J.; Priya, R.

10.1101/2024.07.24.604962 — developmental biology — Posted on 2024-07-30

428 White matter connections of human ventral temporal cortex are organized by cytoarchitecture, eccentricity, and category-selectivity from birth

Kubota, E.; Yan, X.; Tung, S.; Fascendini, B.; Tyagi, C.; Duhameau, S.; Ortiz, D.; Grotheer, M.; Natu, V. S.; Keil, B.; Grill-Spector, K.

10.1101/2024.07.29.605705 — neuroscience — Posted on 2024-07-30

429 Unravelling the neurocognitive mechanisms underlying counterconditioning in humans

Wirz, L.; Houtekamer, M. C.; de Vos, J.; Dunsmoor, J. E.; Homberg, J.; Henckens, M. J. A. G.; Hermans, E.

10.1101/2024.07.29.605706 — neuroscience — Posted on 2024-07-30

430 Galanin receptor 1 expressing neurons in hippocampal-prefrontal circuitry modulate goal directed attention and impulse control

Messanvi, F.; Visocky, V.; Senneca, C.; Berkun, K.; Taori, M.; Bradley, S. P.; Wang, H.; Tejeda, H.; Chudasama, Y.

10.1101/2024.07.29.605653 — neuroscience — Posted on 2024-07-30

431 Multimodal weakly supervised learning to identify disease-specific changes in single-cell atlases

Litinetskaya, A.; Shulman, M.; Hediyeh-zadeh, S.; Moinfar, A. A.; Curion, F.; Szalata, A.; Omidi, A.; Lotfollahi, M.; Theis, F. J.

10.1101/2024.07.29.605625 — bioinformatics — Posted on 2024-07-29

432 Understanding the Pathogenicity of Parkin Catalytic Domain Mutants

Wagner, J. P.; Sauve, V.; Gehring, K.

10.1101/2024.07.29.605699 — biochemistry — Posted on 2024-07-29

433 Conservation, alteration, and redistribution of mammalian striatal interneurons

Corrigan, E. K.; DeBerardine, M.; Poddar, A.; Turrero Garcia, M.; Schmitz, M. T.; Harwell, C.; Paredes, M.; Krienen, F. M.; Pollen, A. A.

10.1101/2024.07.29.605664 — evolutionary biology — Posted on 2024-07-30

434 Evidence for an efferent-based prediction contributing to implicit motor adaptation

Szarka, A.; Kim, H. E.; Inglis, J. T.; Chua, R.

10.1101/2024.07.29.605662 — neuroscience — Posted on 2024-07-30

435 A Regularized Cox Hierarchical Model for Incorporating Annotation Information in Predictive Omic Studies

Shen, D.; Lewinger, J. P.; Kawaguchi, E. S.

10.1101/2024.03.09.584239 — bioinformatics — Posted on 2024-07-29

436 Deciphering Reductive Dehalogenase Specificity Through Targeted Mutagenesis of Chloroalkane Reductases

Picott, K. J.; Bowers, C.; Edwards, E. A.

10.1101/2024.07.29.605694 — biochemistry — Posted on 2024-07-29

437 Carbon monoxide-driven bioethanol production operates via a tungsten-dependent catalyst

Lemaire, O. N.; Belhamri, M.; Shevchenko, A.; Wagner, T.

10.1101/2024.07.29.605569 — biochemistry — Posted on 2024-07-29

438 Oxidation of Four Monoterpenoid Indole Alkaloid Classes by Three Cytochrome P450 Monooxygenases from Tabernaemontana litoralis

Mai, Z.; Kim, K.; Richardson, M. B.; Deschenes, D. A. R.; Garza-Garcia, J. J. O.; Shahsavarani, M.; Perley, J. O.; Njoku, D. I.; Deslongchamps, G.; De Luca, V.; Qu, Y.

10.1101/2024.07.29.605674 — biochemistry — Posted on 2024-07-29

439 Dimer-monomer transition defines a hyper-thermostable peptidoglycan hydrolase mined from bacterial proteome by lysin-derived antimicrobial peptide-primed screening

Zhang, L.; Hu, F.; Zhao, Z.; Li, X.; Zhong, M.; He, J.; Yao, F.; Zhang, X.; Mao, Y.; Wei, H.; He, J.; Yang, H.

10.1101/2024.04.26.591248 — biochemistry — Posted on 2024-07-29

440 Artifacts in single-cell mitochondrial DNA mutation analyses misinform phylogenetic inference

Lareau, C. A.; Chapman, M. S.; Penter, L.; Nawy, T.; Pe'er, D.; Ludwig, L. S.

10.1101/2024.07.28.605517 — genomics — Posted on 2024-07-29

441 Histones are exosome membrane proteins regulated by cell stress

Singh, B.; Sundbom, M. F.; Muthukrishnan, U.; Natarajan, B.; Stransky, S.; Nordin, J. Z.; Wiklander, O. P. B.; Sandblad, L.; Sidoli, S.; EL Andaloussi, S.; Haney, M.; Gilthorpe, J. D.

10.1101/2024.04.08.588575 — cell biology — Posted on 2024-07-29

442 Identification and functional validation of human islet microRNAs associated with donor trait

Wong, W. K.; El-Azzi, I.; Nachanekar, A.; Alvandi, E.; Pham, N. H.; Sara, M.; Cheng, F.; Jiang, G.; Sorensen, A. E.; Chew, Y. V.; Loudovaris, T.; Thomas, H. E.; Ma, R. C.; Hawthorne, W. J.; Dalgaard, L. T.; Joglekar, M. V.; Hardikar, A. A.

10.1101/2022.10.14.512222 — cell biology — Posted on 2024-07-29

443 Enhanced RNAi does not provide efficient innate antiviral immunity in mice in vivo.

Kulmann, M. I. R.; Taborska, E.; Benkoova, B.; Palus, M.; Drobek, A.; Horvat, F.; Pasulka, J.; Malik, R.; Sakyova, E.; Honig, V.; Pellerova, M.; Borsanyiova, M.; Stepanek, O.; Bopegamage, S.; Ruzek, D.; Svoboda, P.

10.1101/2024.07.29.605661 — molecular biology — Posted on 2024-07-29

444 Myocardial infarction injury is exacerbated by nicotine in vape aerosol exposure

Savko, C.; Molinaro, C.; Esquer, C.; Rokaw, S.; Shain, A.; Jaafar, F.; Wright, M.; Phillips, J.; Hopkins, T.; Mikhail, S.; Rieder, A.; Mardani, A.; Bailey, B.; Sussman, M.

10.1101/2024.07.29.605355 — molecular biology — Posted on 2024-07-29

445 Tuning of ribosome levels mediated by RNase I and hibernating ribosomes

Minami, A.; Tanzawa, T.; Yang, Z.; Funatsu, T.; Kuzuyama, T.; Yoshida, H.; Kato, T.; Ogawa, T.

10.1101/2024.07.29.605612 — molecular biology — Posted on 2024-07-29

446 Comparative metabolomics of wild and cultivated yew: insights into metabolic diversity and environmental adaptability

wang, d.; zhang, y.

10.1101/2024.07.29.605693 — molecular biology — Posted on 2024-07-29

447 The ability of human TIM1 to bind phosphatidylethanolamine enhances viral uptake and efferocytosis compared to rhesus and mouse orthologs

Zhang, L.; Kitzmiller, C. E.; Richard, A.; Popli, S.; Choe, H.

10.1101/2024.07.29.605603 — molecular biology — Posted on 2024-07-29

448 A bacterial TIR-based immune system senses viral capsids to initiate defense

Roberts, C.; Fishman, C.; Banh, D.; Marraffini, L. A.

10.1101/2024.07.29.605636 — microbiology — Posted on 2024-07-29

449 Pulsed blue light and phage therapy: A novel synergistic bactericide

Rimon, A.; Belin, J.; Yerushalmy, O.; Alkalay-Oren, S.; Eavri, Y.; Shapochnikov, A.; Coppenhagen-Glazer, S.; Hazan, R.; Gavish, L.

10.1101/2024.07.29.605651 — microbiology — Posted on 2024-07-29

450 Investigation of Bactericidal effect of Earwax on Escherichia coli and Staphylococcus aureus isolated from skin and stool samples of undergraduate students, Federal University of Agriculture Makurdi, Benue State, Nigeria

Tsenongu, A. J.; Ichor, T. S.; Ashar, S. J.; Mena, A. S.; Kwaghve, A.

10.1101/2024.07.29.605580 — microbiology — Posted on 2024-07-29

451 Proteomic analysis of unicellular cyanobacterium Crocosphaera subtropica ATCC 51142 under extended light or dark growth

Panda, P.; Giri, S. J.; Sherman, L. A.; Kihara, D.; Aryal, U. K.

10.1101/2024.07.29.605499 — microbiology — Posted on 2024-07-29

452 Nitrogen Availability and Utilisation of Oligopeptides by Yeast in Industrial Scotch Grain Whisky Fermentation

Berg, H. Y.; Arju, G.; Nisamedtinov, I.

10.1101/2024.07.02.601656 — microbiology — Posted on 2024-07-29

453 The antifungal capacity of an 681-membered collection of environmental yeast isolates

Macia Valero, A.; Tabatabaeifar, F.; Billerbeck, S.

10.1101/2024.07.29.605670 — microbiology — Posted on 2024-07-29

454 Effect of curcumin and 5-bromoindole-3-carboxyaldehyde on the inhibition of Quorum sensig-dependent virulence factors in Pseudomonas aeruginosa

Gonzalez, G. M.; Garcia-Contreras, R.; Garcia Vales, I.; Valdes, N. G.; Lugo Gutierrez, D. A.; Bustamante Martinez, I. L.; Almeida, J.

10.1101/2024.07.29.605599 — microbiology — Posted on 2024-07-29

455 TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by Collectrin-like domain of ACE2

Aggarwal, A.; Fichter, C.; Milogiannakis, V.; Ison, T.; Ruiz Silva, M.; Esneau, C.; Bartlett, N.; Burrell, L.; Patel, S.; Churchill, M.; Angelovich, T.; Parry, R.; Sng, J. D.; Neely, G. G.; Moreno, C. L.; Loo, L.; Kelleher, A. D.; Brilot, F.; Khromykh, A.; Turville, S. G.

10.1101/2023.09.22.558930 — microbiology — Posted on 2024-07-29

456 The ontogeny of immune tolerance: a model of the early-life gut microbiome and adaptive immunity

Tepekule, B.; Lim, A. I.; Metcalf, C. J. E.

10.1101/2024.05.20.594845 — immunology — Posted on 2024-07-29

457 Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)

Hu, J.; Cherkkil, A.; Surinach, D. A.; Oladepo, I.; Hossain, R. F.; Fausner, S.; Saxena, K.; Ko, E.; Peters, R.; Feldkamp, M.; Konda, P. C.; Pathak, V.; Horstmeyer, R.; Kodandaramaiah, S. B.

10.1101/2024.07.04.601964 — neuroscience — Posted on 2024-07-29

458 Functional divergence between the two cerebral hemispheres contributes to human fluid intelligence

Liang, X.; Luo, J.; Yang, L.; Vatansever, D.; Jefferies, E.; Gong, G.

10.1101/2024.04.05.586081 — neuroscience — Posted on 2024-07-29

459 Widespread Autonomic Physiological Coupling Across the Brain-Body Axis

Bolt, T. S.; Wang, S.; Nomi, J. S.; Setton, R.; Gold, B.; Frederick, B.; Chen, J. J.; Picchioni, D.; Spreng, R. N.; Keilholz, S.; Uddin, L.; Chang, C.

10.1101/2023.01.19.524818 — neuroscience — Posted on 2024-07-29

460 Microprism-based two-photon imaging of the lateral cortex of the mouse inferior colliculus reveals novel organizational principles of the auditory midbrain

Ibrahim, B. A.; Shinagawa, Y.; Douglas, A.; Xiao, G.; Asilador, A. R.; Llano, D. A.

10.1101/2022.11.05.515308 — neuroscience — Posted on 2024-07-29

461 Identification of potential SARS-CoV-2 genetic markers resulting from host domestication.

Wisniewski, J.; CHEN, H.-C.

10.1101/2024.07.27.605454 — systems biology — Posted on 2024-07-29

462 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Nwizugbo, D. Z.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.

10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-29

463 Neuronal expression of human amyloid-β and Tau drives global phenotypic and multi-omic changes in C. elegans

Holcom, A.; Fuentealba, M.; Sivapatham, R.; King, C. D.; Osman, H.; Foulger, A.; Bhaumik, D.; Schilling, B.; Furman, D.; Andersen, J. K.; Lithgow, G. J.

10.1101/2023.06.01.542377 — systems biology — Posted on 2024-07-29

464 Haptoglobin and glutamine synthetase may biomark cachexia induced by anti-acute myeloid leukemia chemotherapy

Campelj, D. G.; Timpani, C. A.; Spiesberger, G.; Formosa, L. E.; Steele, J.; Zhang, H.; Schittenhelm, R. B.; Leow, L.; Goodman, C.; Rybalka, E.

10.1101/2024.07.24.604689 — physiology — Posted on 2024-07-29

465 Exploring the Mechanism of Gentiana in Treating Pancreatic Cancer Based on Network Pharmacology and Molecular Docking Techniques

Qian, Y.; Wang, Z.; Ji, J.

10.1101/2024.07.18.604197 — pharmacology and toxicology — Posted on 2024-07-29

466 Novel miRNA-inducing drugs enable differentiation of retinoic acid-resistant neuroblastoma cells

Nguyen, L. D.; Sengupta, S.; Cho, K. I.; Floru, A.; George, R. E.; Krichevsky, A. M.

10.1101/2024.06.05.597584 — cancer biology — Posted on 2024-07-29

467 ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

Rincon-Torroella, J.; Dal Molin, M.; Mog, B.; Han, G.; Watson, E.; Wyhs, N.; Ishiyama, S.; Ahmedna, T.; Minn, I.; Azad, N. S.; Bettegowda, C.; Papadopoulos, N.; Kinzler, K. W.; Zhou, S.; Vogelstein, B.; Gabrielson, K. L.; Sur, S.

10.1101/2023.07.23.550207 — cancer biology — Posted on 2024-07-29

468 CK2 signaling from TOLLIP-dependent perinuclear endosomes is an essential feature of KRAS and NRAS mutant cancers

Basu, S.; Luke, B.; Karim, B.; Martin, N.; Lockett, S.; Das, S.; Andresson, T.; Saylor, K.; Kozlov, S.; Bassel, L.; Esposito, D.; Galloux, M.; Johnson, P. F.

10.1101/2022.04.05.487175 — cancer biology — Posted on 2024-07-29

469 Development of AI-assisted microscopy frameworks through realistic simulation in pySTED

Bilodeau, A.; Michaud-Gagnon, A.; Chabbert, J.; Turcotte, B.; Heine, J.; Durand, A.; Lavoie-Cardinal, F.

10.1101/2024.03.25.586697 — bioinformatics — Posted on 2024-07-29

470 Rapid and accurate genotype imputation from low coverage short read, long read, and cell free DNA sequence

Li, Z.; Albrechtsen, A.; Davies, R. W.

10.1101/2024.07.18.604149 — bioinformatics — Posted on 2024-07-29

471 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases

Ramesh, S.; Rapp, S. L.; Tapias Gomez, J.; Levine, B.; Tapias-Gomez, D.; Chung, D.; Truong, Z.

10.1101/2023.09.20.558722 — bioinformatics — Posted on 2024-07-29

472 Nonenzymatic, prebiotic aminoacylation couples chirality of RNA and protein

Davisson, J. A.; Kalb, E. M.; Knudson, I. J.; Schepartz, A.; Engelhart, A. E.; Adamala, K.

10.1101/2024.07.29.605638 — biochemistry — Posted on 2024-07-29

473 Fast Targeted Metabolomics for Analyzing Metabolic Diversity of Bacterial Indole Derivatives in ME/CFS Gut Microbiome

Tian, H.; Wang, L.; Aiken, E.; Ortega, R. J. V.; Hardy, R.; Placek, L.; Kozhaya, L.; Unutmaz, D.; Oh, J.; Yao, X.

10.1101/2024.07.29.605643 — biochemistry — Posted on 2024-07-29

474 The Histone Chaperone Spn1 Preserves Chromatin Protections at Promoters and Nucleosome Positioning in Open Reading Frames

Tonsager, A. J.; Zukowski, A.; Radebaugh, C. A.; Weirich, A.; Stargell, L. A.; Ramachandran, S.

10.1101/2024.03.14.585010 — genomics — Posted on 2024-07-29

475 Diet of Andean leaf-eared mice (Phyllotis) living at extreme elevations on Atacama volcanoes: insights from metagenomics, DNA metabarcoding, and stable isotopes

Quezada-Romegialli, C.; Quiroga-Carmona, M.; D'Elia, G.; Harrod, C.; Storz, J. F.

10.1101/2024.07.23.604871 — evolutionary biology — Posted on 2024-07-29

476 Phylogenomics resolves the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha)

Deng, J.; Stroinski, A.; Szwedo, J.; Ghanavi, H. R.; Yapar, E.; Franco, D. C.; Prus-Frankowska, M.; Michalik, A.; Wahlberg, N.; Lukasik, P.

10.1101/2024.07.26.605304 — evolutionary biology — Posted on 2024-07-29

477 A suite of selective pressures supports the maintenance of alleles of a Drosophila immune peptide

Mullinax, S. R.; Darby, A. M.; Gupta, A.; Chan, P.; Smith, B.; Unckless, R.

10.1101/2023.08.18.553899 — evolutionary biology — Posted on 2024-07-29

478 Extramacrochaetae regulates Notch signaling in the Drosophila eye through non-apoptotic caspase activity

Baker, N. E.; Nair, S.

10.1101/2023.10.04.560841 — developmental biology — Posted on 2024-07-29

479 The dual Ras Association (RA) Domains of Drosophila Canoe have differential roles in linking cell junctions to the cytoskeleton during morphogenesis

McParland, E.; Gurley, N.; Wolfsberg, L.; Butcher, A.; Bhattarai, A.; Jensen, C.; Johnson, R.; Slep, K.; Peifer, M.

10.1101/2024.07.29.605598 — cell biology — Posted on 2024-07-29

480 The valine-arginine dipeptide repeat protein encoded by mammalian telomeric RNA appears highly expressed in mitosis and may repress global translation

Al-Turki, T.; Mantri, V.; Willcox, S.; Mills, C. A.; Herring, L. E.; Cho, S.-j.; Lee, H.; meyer, C.; Anton, E.; Griffith, J. D.

10.1101/2024.07.24.604971 — molecular biology — Posted on 2024-07-29

481 ComBatLS: A location- and scale-preserving method for multi-site image harmonization

10.1101/2024.06.21.599875 — neuroscience — Posted on 2024-07-29

482 Big Data in Myoelectric Control: LargeMulti-User Models Enable Robust Zero-ShotEMG-based Discrete Gesture Recognition

Eddy, E.; Campbell, E.; Bateman, S.; Scheme, E.

10.1101/2024.07.11.603119 — neuroscience — Posted on 2024-07-29

483 Hemispheric difference of adaptation lifetime in human auditory cortex measured with MEG

Dar, A. H.; Haertwich, N.; Hajizadeh, A.; Brosch, M.; Koenig, R.; May, P. J. C.

10.1101/2024.04.16.588236 — neuroscience — Posted on 2024-07-29

484 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making

Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.

10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-07-29

485 A neural compass in the human brain during naturalistic virtual navigation

Lu, Z.; Julian, J. B.; Aguirre, G. K.; Epstein, R. A.

10.1101/2024.04.18.590112 — neuroscience — Posted on 2024-07-29

486 Increasing spectral DCM flexibility and speed by leveraging Julia's ModelingToolkit and automated differentiation

Hofmann, D.; Chesebro, A. G.; Rackauckas, C.; Mujica-Parodi, L. R.; Friston, K.; Edelman, A.; Strey, H. H.

10.1101/2023.10.27.564407 — neuroscience — Posted on 2024-07-29

487 improv: A software platform for real-time and adaptive neuroscience experiments

Draelos, A.; Loring, M. D.; Nikitchenko, M.; Sriworarat, C.; Gupta, P.; Sprague, D. Y.; Pnevmatikakis, E.; Giovannucci, A.; Benster, T.; Deisseroth, K.; Pearson, J. M.; Naumann, E. A.

10.1101/2021.02.22.432006 — neuroscience — Posted on 2024-07-29

488 Modelling alcohol consumption in rodents using two-bottle choice home cage drinking and optional lickometry-based microstructural analysis

Hou, S.; Arce Soto, N. M.; Glover, E. J.

10.1101/2024.07.19.604367 — neuroscience — Posted on 2024-07-29

489 Relationship between therapeutic activity and preferential targeting of toxic soluble aggregates by amyloid-beta-directed antibodies

Kaplan, J. M.; Gibbs, E.; Coutts, J.; Zhao, B.; Mackenzie, I.; Cashman, N. R.

10.1101/2024.04.20.590412 — neuroscience — Posted on 2024-07-29

490 Exploring the role of cultivar, year and plot age in the incidence of esca and Eutypa dieback: insights from 20 years of regional surveys in France

Etienne, L.; Fabre, F.; Martinetti, D.; Frank, E.; Michel, L.; Bonnardot, V.; Guerin Dubrana, L.; Delmas, C. E. L.

10.1101/2024.03.19.585220 — plant biology — Posted on 2024-07-29

491 Visualization of endogenous G proteins on endosomes and other organelles

Jang, W.; Senarath, K.; Feinberg, G.; Lu, S.; Lambert, N. A.

10.1101/2024.03.05.583500 — pharmacology and toxicology — Posted on 2024-07-29

492 NEW INSIGHTS INTO THE HEPATIC IRON PHENOTYPE OF BMP6 KNOCKOUT MICE

BESSON, C.; WILLEMETZ, A.; LATOUR, C.; ROBERT, L.; COPPIN, H.; ROTH, M.-P.; CANONNE-HERGAUX, F.

10.1101/2023.09.28.559941 — pathology — Posted on 2024-07-29

493 Hepatic Nrf1 (Nfe2l1) promotes VLDL dependent liver defense against sepsis

Trites, M. J.; Li, L.; Akl, M. G.; Hydomako, A.; Widenmaier, S. B.

10.1101/2024.07.04.602118 — pathology — Posted on 2024-07-29

494 How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

Ackermann, J.; Bernard, C.; Sirven, P.; Salmon, H.; Fraldi, M.; Ben Amar, M.

10.1101/2024.01.16.575824 — biophysics — Posted on 2024-07-29

495 Digital Microbe: A Genome-Informed Data Integration Framework for Collaborative Research on Emerging Model Organisms

Veseli, I.; DeMers, M. A.; Cooper, Z. S.; Schechter, M. S.; Miller, S.; Weber, L.; Smith, C. B.; Rodriguez, L. T.; Schroer, W. F.; McIlvin, M. R.; Lopez, P. Z.; Saito, M.; Dyhrman, S.; Eren, A. M.; Moran, M. A.; Braakman, R.

10.1101/2024.01.16.575828 — bioinformatics — Posted on 2024-07-29

496 An Alignment-free Method for Phylogeny Estimation using Maximum Likelihood

Zahin, T.; Abrar, M. H.; Rahman, M.; Tasnim, T.; Bayzid, M. S.; Rahman, A.

10.1101/2019.12.13.875526 — bioinformatics — Posted on 2024-07-29

497 Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells

de Luca, K. L.; Rullens, P. M.; Legube, G.; Kind, J.

10.1101/2023.05.10.540169 — genomics — Posted on 2024-07-29

498 Different coexistence patterns between apex carnivores and mesocarnivores based on temporal, spatial, and dietary niche partitioning analysis in Qilian Mountain National Park, China

Cong, W.; Li, J.; Hacker, C.; Li, Y.; Zhang, Y.; Jin, L.; Zhang, Y.; Li, D.; Xue, Y.; Zhang, Y.

10.1101/2023.08.14.553226 — ecology — Posted on 2024-07-29

499 Widely dispersed clonal expansion of multi-fungicide-resistant Aspergillus fumigatus limits genomic epidemiology prospects

Snelders, E.; Celia-Sanchez, B. N.; Nederlof, Y. C.; Zhang, J.; Kortenbosch, H. H.; Zwaan, B. J.; Tehupeiory-Kooreman, M.; Giraldo Lopez, A.; van Dijk, K.; Wang, L.; Brewer, M. T.; Momany, M.; Auxier, B.; Verweij, P. E.

10.1101/2024.07.29.605539 — microbiology — Posted on 2024-07-29

500 The Lag3 and PD-1 pathways govern TCR signal duration and migration of CD4+ T cells

Sheriff, L.; Copland, A.; Lecky, D. A.; Done, R.; George, L. S.; Jennings, E. K.; Rouvray, S.; Elliot, T. A.; Jinks, E. S.; Pallan, L.; Bending, D.

10.1101/2024.06.06.597762 — immunology — Posted on 2024-07-29

501 Optimal placement of high-channel visual prostheses in human retinotopic visual cortex

van Hoof, R.; Lozano, A.; Wang, F.; Klink, P. C.; Roelfsema, P. R.; Goebel, R.

10.1101/2024.03.05.583489 — neuroscience — Posted on 2024-07-29

502 Mechano-mediated M2 macrophage polarization and immune suppression in stiffened tumor microenvironment

Sapudom, J.; Tipay, P. S.; Teo, J.

10.1101/2024.07.29.605566 — bioengineering — Posted on 2024-07-29

503 Narrow window data-independent acquisition on the Orbitrap Astral Mass Spectrometer enables fast and deep coverage of the plasma glycoproteome

Jager, S.; Zeller, M.; Pashkova, A.; Schulte, D.; Damoc, E.; Reiding, K.; Makarov, A. A.; Heck, A. J. R.

10.1101/2024.07.29.605591 — biochemistry — Posted on 2024-07-29

504 Harnessing in vivo Synthesis of Bioactive Multiarylmethanes in Escherichia coli via Oxygen-Mediated Free Radical Reaction Induced by Simple Phenols

Wang, D.; He, J.; Chen, Y.; Liu, B.; Wu, Z.; Pan, X.; Niu, X.

10.1101/2024.07.29.605594 — biochemistry — Posted on 2024-07-29

505 Arc controls organ architecture through modulation of Crb and MyoII

Kim, J. H.; Maruyama, R.; Kim, K.; Vertrees, D.; Paul, P.; Britson, K. A.; Andrew, D. J.

10.1101/2024.07.29.605562 — developmental biology — Posted on 2024-07-29

506 The Small GTPase Rho5 - Yet Another Player in Yeast Glucose Signaling

Schweitzer, F.; Bischof, L.; Walter, S.; Morris, S.; Schmitz, H.-P.; Heinisch, J. J.

10.1101/2024.07.29.605593 — molecular biology — Posted on 2024-07-29

507 High-fat and high-sucrose diet-induced hypothalamic inflammation shows sex specific features in mice

De Paula, G. C.; Simoes, R. F.; Garcia-Serrano, A. M.; Duarte, J. M. N.

10.1101/2024.07.29.605582 — molecular biology — Posted on 2024-07-29

508 Thermophilic Fungus Uses Anthraquinones to Modulate Ferrous Excretion, Sterol-Mediated Endocytosis and Iron Storage in Response to Cold Stress

Li, S.; Wang, D.; He, J.; Liao, C.; Zuo, Z.; Li, S.; Niu, X.

10.1101/2024.07.29.605589 — microbiology — Posted on 2024-07-29

509 Fucosylated and non-fucosylated alpha2,3 sialosides were detected on the bovine mammary gland tissues

Hiono, T.; Morita, T.; Kosenda, K.; Otani, Y.; Ichii, O.; Isoda, N.; Sakoda, Y.

10.1101/2024.07.29.605565 — microbiology — Posted on 2024-07-29

510 Hypersensitivity controlled by mir-9a modulates female receptivity of Drosophila melanogaster.

Zhang, X.; Bagley, J.; Huang, Y.; Kim, W. J.

10.1101/2024.07.29.605583 — neuroscience — Posted on 2024-07-29

511 Brown Adipose Tissue undergoes pathological perturbations and shapes C2C12 myoblast homeostasis in the SOD1-G93A mouse model of Amyotrophic Lateral Sclerosis.

Rosina, M.; Scaricamazza, S.; Riggio, F.; Fenili, G.; Giannessi, F.; Matteocci, A.; Nesci, V.; Salvatori, I.; Angelini, D. F.; AQUILANO, K.; Chiurchiu, V.; Lettieri Barbato, D.; Mercuri, N. B.; Valle, C.; Ferri, A.

10.1101/2024.07.29.605540 — neuroscience — Posted on 2024-07-29

512 CUT&Tag for high-resolution epigenomic profiling from a low amount of Arabidopsis tissue

Fu, Y.; Schmid, M. W.; Simonini, S.

10.1101/2024.07.29.604300 — plant biology — Posted on 2024-07-29

513 MACanalyzeR: scRNA-seq Analysis Tool Reveals PPARγHI Lipid-Associated Macrophages Facilitate Thermogenic Expansion in BAT

Ninni, A.; Zaccaria, F.; Verteramo, L.; Sciarretta, F.; Silveira, L. S.; Rosa-Neto, J. C.; Grumati, P.; Rizzo, G.; Cochain, C.; Williams, J. W.; Ivanov, S.; Zhou, B.; Aquilano, K.; Lettieri-Barbato, D.

10.1101/2024.07.29.605588 — physiology — Posted on 2024-07-29

514 Rapid liquid biopsy assessment through gene profiling from the kidney biopsy transport medium: a technical validation and a proof-of-concept pilot study

Li, Z.; Welters, M. J. P.; de Vries, A. P. J.; Bruijn, J. A.; Baelde, H. J.; Kers, J.

10.1101/2024.07.28.604919 — pathology — Posted on 2024-07-29

515 Structural transitions in kinesin minus-end directed microtubule motility

Shibata, S.; Wang, M. Y.; Imasaki, T.; Shigetmatsu, H.; Wei, Y.; Jobichen, C.; Hagio, H.; Sivaraman, J.; Endow, S. A.; Nitta, R.

10.1101/2024.07.29.605428 — biophysics — Posted on 2024-07-29

516 Detection of Potential Phytochemicals against ctxAB Toxin to Combat Cholera

Akter, Y.; Rahman, K.; Reza, M. S.; Al-Mamun, A.; Alam, M.; Mollah, M. N. H.; MONIR, M. M.

10.1101/2024.07.29.605560 — bioinformatics — Posted on 2024-07-29

517 The Role of TandemHeartTM combined with ProtekDuoTM as Right Ventricular Support Device: A Simulation Approach

De Lazzari, B.; Badagliacca, R.; Capoccia, M.; Maybauer, M. O.; De Lazzari, C.

10.1101/2024.07.29.604074 — bioengineering — Posted on 2024-07-29

518 Mechanistic basis of temperature-adaptation in microtubule dynamics across frog species

Troman, L.; de Gaulejac, E.; Biswas, A.; Stiens, J.; Kuropka, B.; Moores, C.; Reber, S.

10.1101/2024.07.29.605571 — biochemistry — Posted on 2024-07-29

519 Nucleoside diphosphate kinase A (NME1) catalyze its own oligophosphorylation

Celik, A.; Schoepf, F.; Stieger, C. E.; Morgan, J. A. M.; Lampe, S.; Ruwolt, M.; Liu, F.; Hackenberger, C. P. R.; Roderer, D.; Fiedler, D.

10.1101/2024.07.29.605581 — biochemistry — Posted on 2024-07-29

520 Chromosome-level reference genome for the medically important Arabian horned viper (Cerastes gasperettii)

Mochales Riano, G.; Hirst, S. R.; Talavera, A.; Burriel-Carranza, B.; Pagone, V.; Estarellas, M.; Busschau, T.; Boissinot, S.; Hogan, M. P.; Tena-Garces, J.; Pla, D.; Calvete, J. J.; Els, J.; Margres, M. J.; Carranza, S.

10.1101/2024.07.29.605543 — genomics — Posted on 2024-07-29

521 SegColR: Deep Learning for Automated Segmentation and Color Extraction

Boyko, J.

10.1101/2024.07.28.605475 — evolutionary biology — Posted on 2024-07-29

522 Designing a simple and efficient phage biocontainment system using the amber suppressor

Tsoumbris, P. R.; Vincent, R.; Jaschke, P. R.

10.1101/2024.07.29.605542 — microbiology — Posted on 2024-07-29

523 ADAR1 p150 prevents HSV-1 from triggering PKR/eIF2alpha-mediated translational arrest and is required for efficient viral replication

Jurak, I.; Parchure, A. A.; Cesarec, M.; Ivanisevic, V.; Cunko, M.; Bursac, S.; de Reuver, R.; Rosani, U.; Volarevic, S.; Maelfait, J.

10.1101/2024.07.29.605561 — microbiology — Posted on 2024-07-29

524 Resource-efficiency of cyanobacterium production on Mars: Assessment and paths forward

Ramalho, T. P.; Baumgartner, V.; Kunst, N.; Rodrigues, D.; Bohuon, E.; Leroy, B.; Pillot, G.; Heinicke, C.; Kerzenmacher, S.; Avila, M.; Verseux, C.

10.1101/2024.07.29.605555 — microbiology — Posted on 2024-07-29

525 L-Phenylalanine is a metabolic checkpoint of human Th2 cells

Kulkarni, A.; Rodriguez-Coira, J.; Stocker, N.; Radzikowska, U.; Garcia-Civico, A. J.; Delgado-Dolset, M. I.; Contreras, N.; Jardon-Parages, I.; Saiz-Sanchez, V.; Serrano, P.; Izquierdo, E.; Gomez-Casado, C.; Sanchez-Solares, J.; Pablo-Torres, C.; Obeso, D.; Moreno-Aguilar, C.; Luisa Espinazo, M.; Eljaszewicz, A.; Koch, J.; Baerenfaller, K.; Heider, A.; Tan, G.; Escribese, M. M.; Ruiz-Leon, B.; Akdis, C. A.; Arguello, R. J.; Barber, D.; Villasenor, A.; Sokolowska, M.

10.1101/2024.07.29.605231 — immunology — Posted on 2024-07-29

526 The connectional diaschisis and normalization of cortical language network dynamics after basal ganglia and thalamus stroke

Chen, Q.; Guo, X.; Zhong, T.; Yang, J.; Gao, X.; Hu, Z.; Li, J.; Liu, J.; Wang, Y.; Qu, Z.; Li, W.; Li, Z.; Li, W.; Huang, Y.; Chen, J.; Wen, H.; Zhang, Y.; Yuan, B.; Gao, H.

10.1101/2024.07.29.605538 — neuroscience — Posted on 2024-07-29

527 Quantitative assessment and spatial distribution of Plasmopara viticola oospores in vineyard soil

Poeydebat, C.; Courchinoux, E.; Demeaux, I.; Rodriguez, M.; Chataigner, A.; Lelievre, M.; Goutouly, J.-P.; Rossi, J.-P.; Raynal, M.; Deliere, L.; Francois, D.

10.1101/2024.07.29.605284 — plant biology — Posted on 2024-07-29

528 Odor-based real-time detection and identification of pests and diseases attacking crop plants

Arce, C. M.; Mamin, M.; Roder, G.; Kanagendran, A.; Degen, T.; Defossez, E.; Rasmann, S.; AKIYAMA, T.; MINAMI, K.; YOSHIKAWA, G.; Lopez-Hilfiker, F.; Cappellin, L.; Turlings, T.

10.1101/2024.07.29.605549 — plant biology — Posted on 2024-07-29

529 The prion-like protein Doppel: A soluble biomarker steering ovarian cancers peritoneal to circulatory dissemination

Al-Hilal, T.; Azam, M. Z.; Zhang, X.; Wahab, R.; Hasan, M. M.; Kang, B.; Hassan, M. M.; Karim, M.; Choi, J. U.; Rana, M.; Zhang, J.-Y.; Roy, S.; Byun, Y.; Kim, I.-S.; Song, J. Y.; Alam, F.; Toy, E. P.; Reddy, S. Y.

10.1101/2024.07.26.605386 — cancer biology — Posted on 2024-07-29

530 A comprehensive analysis of the potential biological functions and prognostic values of SREBF1 for multiple cancer types including colorectal cancer

Li, D.; Xu, F.; Cai, Q.; Lin, L.; Zhou, X.; Li, L.; Chen, Y.; Feng, T.; Gan, Y.; Zhang, C.; Yang, F.

10.1101/2024.07.26.605404 — cancer biology — Posted on 2024-07-29

531 Computational Screening of Zanthoxylum armatum DC Phytochemicals for Inhibiting Mutant P53 in Throat Cancer Therapy

Taring, A.; Singpho, S. W.; Lamu, L.; Kalita, B. C.; Tag, H.; Hui, P. K.

10.1101/2024.07.26.605249 — bioinformatics — Posted on 2024-07-29

532 Exploration of Flavonoids to identify Potential Therapeutic Compounds by Targeting the Non-Structural V protein of Nipah Virus

Ahmad, S. R.; Zeyaullah, M.; AlShahrani, A. M.; Khan, M. S.; Ali, H.; Muzammil, K.; Mohieldin, A.; AG Altijani, A.; Dawria, A.; Mohamed, A. O. A.; Kalam, A.

10.1101/2024.07.29.605559 — biochemistry — Posted on 2024-07-29

533 Consistent long-distance foraging flights across years and seasons at colony level in a Neotropical bat

Calderon Capote, M. C.; van Toor, M. L.; O'Mara, T.; Bayer, T.; Crofoot, M.; Dechmann, D.

10.1101/2024.07.29.605243 — animal behavior and cognition — Posted on 2024-07-29

534 MitoNEET reduces the mitochondrial oxidative phosphorylation during epithelial-mesenchymal transition

Handa, H.; Onodera, Y.; Oikawa, T.; Takada, S.; Ueda, K.; Setoyama, D.; Yokota, T.; Yamasaki, M.; Watanabe, M.; Fumoto, Y.; Hashimoto, A.; Hata, S.; Murakami, M.; Sabe, H.

10.1101/2024.07.29.603210 — cell biology — Posted on 2024-07-29

535 Nomination of a novel plasma protein biomarker panel capable of classifying Alzheimer's disease dementia with high accuracy in an African American cohort

Kuchenbecker, L. A.; Thompson, K. J.; Hurst, C. D.; Opdenbosch, B. M.; Heckman, M. G.; Reddy, J. S.; Nguyen, T.; Casellas, H. L.; Reddy, D. J.; Lucas, J. A.; Day, G. S.; Willis, F. B.; Graff-Radford, N. R.; Ertekin-Taner, N.; Kalari, K. R.; Carrasquillo, M. M.

10.1101/2024.07.27.605373 — neuroscience — Posted on 2024-07-29

536 First record of Venturia canescens GRAVENHORST, 1829 (Hymenoptera: Ichneumonidae: Campopleginae) from Tunisia

Zeiri, A.

10.1101/2024.07.25.605196 — zoology — Posted on 2024-07-29

537 Native proteomics by capillary zone electrophoresis-mass spectrometry

Wang, Q.; Wang, Q.; Qi, Z.; Moeller, W.; Wysocki, V. H.; Sun, L.

10.1101/2024.04.24.590970 — systems biology — Posted on 2024-07-29

538 Comparative Analysis of Antioxidant Activity, ROS, and Relative Water Content Between Red and Green Cabbage

Sojib, M. R.; Methela, N. J.; Das, B.; Siddique, M. N. A.; Jone, M. J. H.

10.1101/2024.07.27.605406 — plant biology — Posted on 2024-07-29

539 Stem cell mechanoadaptation - Part A - Effect of microtubule stabilization and volume changing stresses on cytoskeletal remodeling

Putra, V. L.; Kilian, K. A.; Knothe Tate, M. L.

10.1101/2024.07.28.605421 — cell biology — Posted on 2024-07-29

540 Synergy and antagonism in the integration of BCR and CD40 signals that control B-cell proliferation

Huang, H.; Vaidehi Narayanan, H.; Hoffmann, A.

10.1101/2024.07.28.605521 — immunology — Posted on 2024-07-29

541 Neural specialisation for concrete and abstract concepts revealed through meta-analysis

Hoffman, P.; Bair, M.

10.1101/2024.07.11.603079 — neuroscience — Posted on 2024-07-29

542 Using DeepLabCut-Live to probe state dependent neural circuits of behavior with closed-loop optogenetic stimulation

Gonzalez, M.; Gradwell, M. A.; Thackray, J. K.; Patel, K. R.; Temkar, K. K.; Abraira, V. E. G.

10.1101/2024.07.28.605489 — neuroscience — Posted on 2024-07-29

543 Deliberative Behaviors and Prefrontal-Hippocampal Coupling are Disrupted in a Rat Model of Fetal Alcohol Spectrum Disorders

Rosenblum, H. L.; Kim, S.; Stout, J. J.; Klintsova, A.; Griffin, A. L.

10.1101/2024.07.28.605480 — neuroscience — Posted on 2024-07-29

544 Proteomic analysis reveals the dominant effect of ipomoeassin F on the synthesis of membrane and secretory proteins in triple-negative breast cancer cells

Sicairos, B.; Zhou, J.; Hu, Z.; Zhang, Q.; Shi, W. Q.; Du, Y.

10.1101/2024.07.28.605505 — cancer biology — Posted on 2024-07-29

545 Unraveling the Role of Azobenzene-Based Photoswitchable Lipids in Controlling Innate Immune Response

Delova, A.; Makhloutah, A.; Bernhard, Y.; Pasc, A.; MONARI, A.

10.1101/2024.07.28.605494 — biophysics — Posted on 2024-07-29

546 Modulation of Electrostatic Interactions as a Mechanism of Cryptic Adaptation of Colwellia to High Hydrostatic Pressure

Makhatadze, G. I.

10.1101/2024.07.28.605522 — biophysics — Posted on 2024-07-29

547 Caught in the act of triplication: TNF superfamily

Menon, N.; K, K.; Goswami, M.; Singh, A.; Srinivasan, S.

10.1101/2024.07.27.603686 — bioinformatics — Posted on 2024-07-29

548 CardioMEA: Comprehensive Data Analysis Platform for Studying Cardiac Diseases and Drug Responses

Lee, J.; Duperrex, E.; El-Battrawy, I.; Hohn, A.; Saguner, A. M.; Duru, F.; Emmenegger, V.; Cyganek, L.; Hierlemann, A.; Ulusan, H.

10.1101/2024.07.28.605490 — bioengineering — Posted on 2024-07-29

549 Parallel evolution of methyltransferases leads to vobasine biosynthesis in Tabernaemontana elegans and Catharanthus roseus

Farzana, M.; Richardson, M. B.; Deschenes, D. A. R.; Mai, Z.; Njoku, D. I.; Deslongchamps, G.; Qu, Y.

10.1101/2024.07.28.605509 — biochemistry — Posted on 2024-07-29

550 Mitogenomic phylogeny and divergence time estimation of Artemia leach, 1819 (Branchiopoda: Anostraca) with emphasis on parthenogenetic lineages

Asem, A.; Yang, C.; De Vos, S.; Mahmoudi, F.; Lidong, X.; Shen, C.-Y.; Hontoria, F.; Rogers, D. C.; Gajardo, G.

10.1101/2024.07.26.600140 — evolutionary biology — Posted on 2024-07-29

551 Introgression dynamics of sex-linked chromosomal inversions shape the Malawi cichlid adaptive radiation

Blumer, L. M.; Burskaia, V.; Artiushin, I.; Saha, J.; Camacho Garcia, J.; Elkin, J.; Fischer, B.; Zhou, C.; Gresham, S.; Malinsky, M.; Linderoth, T.; Sawasawa, W.; Bista, I.; Hickey, A.; Kucka, M.; Louzada, S.; Zatha, R.; Yang, F.; Rusuwa, B.; Santos, M. E.; Chan, Y. F.; Joyce, D. A.; Böhne, A.; Miska, E. A.; Ngochera, M.; Turner, G. F.; Durbin, R.; Svardal, H.

10.1101/2024.07.28.605452 — evolutionary biology — Posted on 2024-07-29

552 Estimating Species-specific U.S. Waterfowl Harvest

Augustine, B.; Royle, J. A.

10.1101/2024.07.27.603620 — ecology — Posted on 2024-07-29

553 MicroRNA miR-92b-3p regulation of a cardiovascular gene regulatory network in the developing branchial arches

Goldsworthy, S.; Losa, M.; Bobola, N.; Griffiths-Jones, S.

10.1101/2024.07.28.605500 — developmental biology — Posted on 2024-07-29

554 Direct quantification of condensate material properties in live cells reveals the regulation of synapsin condensates viscoelasticity by alpha-synuclein

Wang, H.; Hoffmann, C.; Tromm, J. V.; Su, X.; Elliott, J.; Wang, H.; Baum, J.; Pang, Z. P.; Milovanovic, D.; Shi, Z.

10.1101/2024.07.28.605529 — cell biology — Posted on 2024-07-29

555 The dynamic crosstalk between cytoskeletal filaments regulates the cytoplasmic mechanics across the apicobasal axis

Ray, D.; Sinha, D. K.

10.1101/2024.07.23.604784 — cell biology — Posted on 2024-07-29

556 Trapping Devices of Carnivorous Fungus Arthrobotrys oligospora is a Phenotypic System for Isolating Heat-Triggered Excess Irons

Zhou, J.; Wu, Q.; Wu, L.; Yan, J.; Cheng, Q.; Wang, D.; Niu, X.

10.1101/2024.07.25.605209 — microbiology — Posted on 2024-07-29

557 Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida

He, M.; Tao, Y.; Mu, K.; Feng, H.; Fan, Y.; Liu, T.; Huang, Q.; Xiao, Y.; Chen, W.

10.1101/2024.07.28.605504 — microbiology — Posted on 2024-07-29

558 Aging trajectories of memory CD8+ T cells differ by their antigen specificity

Sturmlechner, I.; Jain, A.; Hu, B.; Jadhav, R.; Cao, W.; Okuyama, H.; Tian, L.; Weyand, C.; Goronzy, J.

10.1101/2024.07.26.605197 — immunology — Posted on 2024-07-29

559 Lifespan Oscillatory Dynamics in Lexical Production: A Population-based MEG Resting-State Analysis

Guichet, C.; Harquel, S.; Achard, S.; Mermillod, M.; Baciu, M.

10.1101/2024.07.28.605484 — neuroscience — Posted on 2024-07-29

560 Monkey lateral prefrontal cortex subregions differentiate between perceptual exposure to visual stimuli

Leaman, K.; Yusif Rodriguez, N.; Ahuja, A.; Basu, D.; McKim, T. H.; Desrochers, T. M.

10.1101/2024.07.28.605513 — neuroscience — Posted on 2024-07-29

561 Cognitive sequences in obsessive-compulsive disorder are supported by frontal cortex ramping activity and mediated by symptom severity

Doyle, H.; Garnaat, S. L.; McLaughlin, N.; Desrochers, T. M.

10.1101/2024.07.28.605508 — neuroscience — Posted on 2024-07-29

562 From circuits to lifespan: translating mouse and human timelines with neuroimaging based tractography

Cottam, N.; Ofori, K.; Bryant, M.; Rogge, J.; Hekmatyar, K.; Sun, J.; Charvet, C. J.

10.1101/2024.07.28.605528 — neuroscience — Posted on 2024-07-29

563 Characterizing microglial signaling dynamics during inflammation using single-cell mass cytometry

Kumar, S.; Kahle, A. D.; Keeler, A. B.; Zunder, E. R.; Deppmann, C. D.

10.1101/2024.07.27.605444 — neuroscience — Posted on 2024-07-29

564 Differential Patterns of Gut and Oral Microbiomes in Hispanic Individuals with Cognitive Impairment

Wadop Ngouongo, Y.; Vasquez, E. L.; Mathews, J. J.; Muhammad, J. A. S.; Mavarez, R. P.; Satizabal, C.; Gonzales, M. M.; Tanner, J.; Maestre, G.; Fonteh, A. N.; Seshadri, S.; Kautz, T. F.; Fongang, B.

10.1101/2024.07.27.605455 — neuroscience — Posted on 2024-07-29

565 Maintenance of taste receptor cell presynaptic sites requires gustatory nerve fibers

Landon, S. M.; Holder, E.; Ng, A.; Wood, R. M.; Gutierrez Kuri, E.; Pinto, L.; Humayun, S.; Macpherson, L. J.

10.1101/2024.07.28.604832 — neuroscience — Posted on 2024-07-29

566 Early life psychosocial stress increases binge-like ethanol consumption and alters microglia and brain macrophage population density in early adulthood

Gironda, S. C.; Weiner, J. L.

10.1101/2024.07.27.605403 — neuroscience — Posted on 2024-07-29

567 AraRoot - A Comprehensive Genome-Scale Metabolic Model for the Arabidopsis Root System.

Esterhuizen, L.; Ampimah, N.; Yandeau-Nelson, M.; Nikolau, B. J.; Sparks, E. E.; Saha, R.

10.1101/2024.07.28.605515 — systems biology — Posted on 2024-07-29

568 Biregional division angles generate sharp apex and concave joints in leaves

Wang, Z.; Inoue, Y.; Mochizuki, A.; Tsukaya, H.

10.1101/2024.07.28.605531 — plant biology — Posted on 2024-07-29

569 The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract

Pineros, L.; Frolov, N.; Ruiz-Reynes, D.; Van Eynde, A.; Cavin-Meza, G. J.; Heald, R.; Gelens, L.

10.1101/2024.07.28.605512 — biophysics — Posted on 2024-07-29

570 Degradability tunes ECM stress relaxation and cellular mechanics

Narasimhan, B. N.; Fraley, S. I.

10.1101/2024.07.28.605514 — biophysics — Posted on 2024-07-29

571 Protein surface chemistry encodes an adaptive resistance to desiccation

Romero-Perez, P. S.; Moran, H. M.; Horani, A.; Truong, A.; Manriquez-Sandoval, E.; Ramirez, J. F.; Martinez, A.; Golub, E.; Hunter, K.; Lotthammer, J. M.; Emenecker, R. J.; Boothby, T. C.; Holehouse, A. S.; Fried, S. D.; Sukenik, S.

10.1101/2024.07.28.604841 — biophysics — Posted on 2024-07-29

572 Investigating Medin Cleavage Accessibility in MfgE8: Conformational Insights Derived from Molecular Dynamics Simulations and AlphaFold2 Models

Mesdaghi, S.; Price, R.; Madine, J.; Migrino, R.; Li, M.; Rigden, D. J.

10.1101/2024.07.27.605412 — bioinformatics — Posted on 2024-07-29

573 Refining dual RNA-seq mapping: sequential and combined approaches in host-parasite plant dynamics

Fruggiero, C.; Aufiero, G.; D'Angelo, D.; Pasolli, E.; D'Agostino, N.

10.1101/2024.07.28.605052 — bioinformatics — Posted on 2024-07-29

574 PerturbAtlas: A Comprehensive Atlas of Public Genetic Perturbation Bulk RNA-seq Datasets

Zhang, Y.; Zhang, T.; Yang, G.; Pan, Z.; Tang, M.; He, P.; Wen, Y.; Wang, Y.; Zhou, R.

10.1101/2024.07.28.605482 — bioinformatics — Posted on 2024-07-29

575 User-friendly exploration of epigenomic data in single cells using sincei

Bhardwaj, V.; Mourragui, S.

10.1101/2024.07.27.605424 — bioinformatics — Posted on 2024-07-29

576 Determining mesoscale chromatin structure parameters from spatially correlated cleavage data using a coarse-grained oligonucleosome model

Clerkin, A. B.; Pagane, N.; West, D. W.; Spakowitz, A. J.; Risca, V. I.

10.1101/2024.07.28.605011 — genomics — Posted on 2024-07-29

577 Genetic diversity and evolution of rice centromeres

Xie, L.; Huang, Y.; Huang, W.; Shang, l.; Sun, Y.; Chen, Q.; Bi, S.; Suo, M.; Zhang, S.; Yang, C.; Zheng, X.; Jin, W.; Qian, Q.; Fan, L.; Dongya, W.

10.1101/2024.07.28.605524 — genetics — Posted on 2024-07-29

578 A path analysis disentangling determinants of natal dispersal in a cooperatively breeding bird

Borger, M. J.; Lee, K. G. L.; Weissing, F. J.; Richardson, D. S.; Dugdale, H. L.; Burke, T.; Pen, I.; Komdeur, J.

10.1101/2024.07.26.605387 — ecology — Posted on 2024-07-29

579 Deep learning-based detector of invasive alien frogs, Polypedates leucomystax and Rhinella marina, on an island at invasion front

Kimura, K.; Fukuyama, I.; Fukuyama, K.

10.1101/2024.07.27.605431 — ecology — Posted on 2024-07-29

580 Disentangling the mutational effects on protein stability and interaction of human MLH1

Larsen-Ledet, S.; Stein, A.

10.1101/2024.07.28.605491 — molecular biology — Posted on 2024-07-29

581 In silico screening by AlphaFold2 program revealed the potential binding partners of nuage-localizing proteins and piRNA-related proteins

Kawaguchi, S.; Xu, X.; Soga, T.; Yamaguchi, K.; Kawasaki, R.; Shimouchi, R.; Date, S.; Kai, T.

10.1101/2024.07.28.605023 — molecular biology — Posted on 2024-07-29

582 IPMK Deficiency Reduces Skeletal Muscle Oxidative Metabolism and Exercise Capacity

Lee, J.-H.; Jung, I.-R.; Tu-Sekine, B.; Jin, S.; Anokye-Danso, F.; Ahima, R. S.; Kim, S. F.

10.1101/2024.07.28.605526 — molecular biology — Posted on 2024-07-29

583 A retrograde transit filter mediated by optineurin controls mitostasis in distal axons

Marahori, N. A.; Gailer, B.; Schifferer, M.; Kleele, T.; Iatroudi, A.; Hannan, S. B.; Avramopoulos, P.; Engelhardt, S.; Lakadamyali, M.; Brill, M. S.; Misgeld, T.

10.1101/2024.07.28.604753 — cell biology — Posted on 2024-07-29

584 Mapping the nuclear landscape with multiplexed super-resolution fluorescence microscopy

Rahman, F.; Augoustides, V.; Tyler, E.; Daugird, T. A.; Arthur, C.; Legant, W. R.

10.1101/2024.07.27.605159 — cell biology — Posted on 2024-07-29

585 Stem cell mechanoadaptation Part B - Microtubule stabilization and substrate compliance effects on cytoskeletal remodeling

Putra, V. D.; Kilian, K. A.; Knothe Tate, M. L.

10.1101/2024.07.28.605537 — cell biology — Posted on 2024-07-29

586 Saturation transposon mutagenesis enables genome-wide identification of genes required for growth and fluconazole resistance in the human fungal pathogen Cryptococcus neoformans

Billmyre, R. B.; Craig, C.; Lyon, J. W.; Reichardt, C.; Eickbush, M. T.; Zanders, S. E.

10.1101/2024.07.28.605507 — microbiology — Posted on 2024-07-29

587 Fundamental limitations of kilohertz-frequency carriers in afferent fiber recruitment with transcutaneous spinal cord stimulation

Keesey, R.; Hofstoetter, U.; Hu, Z.; Lombardi, L.; Hawthorn, R.; Bryson, N. K.; Rowald, A.; Minassian, K.; Seanez, I.

10.1101/2024.07.26.603982 — neuroscience — Posted on 2024-07-29

588 Evaluating phasic transcutaneous vagus nerve stimulation (taVNS) with pupil dilation: the importance of stimulation intensity and sensory perception

Ludwig, M.; Pereira, C.; Keute, M.; Duezel, E.; Betts, M. J.; Haemmerer, D.

10.1101/2024.07.27.605407 — neuroscience — Posted on 2024-07-29

589 Proliferative arrest induces neuron differentiation and innate immune responses in control and Creutzfeldt-Jakob Disease agent infected rat septal neurons

pagano, n.; aguilar, g.; Garcia-Milian, R.; manuelidis, l.

10.1101/2024.07.26.605349 — neuroscience — Posted on 2024-07-29

590 Abnormal multisensory facilitation patterns relate to disorganized thinking severity and cognitive decline in schizophrenia

Rogge-Obando, K.; Coffman, B.; Stephen, J.

10.1101/2024.07.26.605377 — neuroscience — Posted on 2024-07-29

591 Synaptogyrin-3 Prevents Cocaine Addiction and Dopamine Deficits

Peck, E. G.; Holleran, K. M.; Curry, A. M.; Holter, K. M.; Estave, P.; Sens, J. P.; Locke, J.; Ortelli, O.; George, B.; Dawes, M.; West, A. M.; Alexander, N.; Kiraly, D.; Farris, S.; Gould, R. W.; McCool, B.; Jones, S. R.

10.1101/2024.07.27.605436 — neuroscience — Posted on 2024-07-29

592 Dopamine reveals adaptive learning of actions representation

Come, M.; Gulmez, A.; Keshishian, L.; Jehl, J.; Bousseyrol, E.; Didienne, S.; Vicq, E.; Le Borgne, T.; Mourot, A.; Faure, P.

10.1101/2024.07.28.605479 — neuroscience — Posted on 2024-07-29

593 Encoding of antennal position and velocity by the Johnstons organ in hawkmoths

Mukunda, C. L.; Sane, S. P.

10.1101/2024.07.28.605492 — neuroscience — Posted on 2024-07-29

594 Imaging of developing human brains with ex vivo PSOCT and dMRI

Wang, H.; Blanke, N.; Gong, D.; Ortug, A.; Alatorre Warren, J. L.; Clickner, C.; Ammon, W.; Nolan, J.; Cotronis, Z.; van der Kouwe, A.; Takahashi, E.

10.1101/2024.07.27.605383 — neuroscience — Posted on 2024-07-29

595 Single field evolution rule governs the dynamics of representational drift in mouse hippocampal dorsal CA1 region.

Chen, C.; Yao, S.; Cheng, S.; Li, A. A.; Yan, Y.; Zhang, X.; Liu, Y.; Wang, Y.; Cao, Q.; Miao, C.

10.1101/2024.07.27.605419 — neuroscience — Posted on 2024-07-29

596 Selective Effects of Ongoing Alpha-Band Activity on Magno- and Parvo-Mediated Detection

Pilipenko, A.; Samaha, J.

10.1101/2024.07.28.605527 — neuroscience — Posted on 2024-07-29

597 A common pathway controls cell size in the sepal and leaf epidermis leading to a non-random pattern of giant cells

Clark, F. K.; Weissbart, G.; Wang, X.; Harline, K.; Li, C.-B.; Formosa-Jordan, P.; Roeder, A. H. K.

10.1101/2024.07.26.605215 — plant biology — Posted on 2024-07-29

598 Rapid oxygen titration following cardiopulmonary resuscitation mitigates cerebral overperfusion and striatal mitochondrial dysfunction in asphyxiated newborn lambs

Badurdeen, S.; Galinsky, R.; Roberts, C.; Crossley, K. J.; Zahra, V.; Thiel, A.; Pham, Y.; Davis, P.; Hooper, S. B.; Polglase, G.; Camm, E.

10.1101/2024.07.27.603805 — physiology — Posted on 2024-07-29

599 Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer cell lines and isogenic models

Adams, K. M.; Wendt, J.-R.; Wood, J.; Olson, S.; Moreno, R.; Jin, Z.; Gopalan, S.; Lang, J. D.

10.1101/2024.07.26.605381 — cancer biology — Posted on 2024-07-29

600 Overcrowding Drives Tumor Invasion by Inducing Nanotopographical Transition of Plasma Membrane

Zhao, X.; Tan, M.; Li, L.; Lin, X.; Li, Z.; Wang, X.; Song, B.; Guo, Z.; Chen, T.; Hou, S.; Fan, J.; Wang, S.; Zhang, Y.; Fan, Y.; Du, J.

10.1101/2024.07.28.605413 — cancer biology — Posted on 2024-07-29

601 Accurate, fast and memory efficient quantification of immune cell phenotypes in cytometry using machine learning

Exner, T.; Hackert, N. S.; Pohl, F.; Osmanusta, G.; Schmidt, F.; Lorenz, H.-M.; Wabnitz, G.; Schett, G.; Graw, F.; Henes, J.; Grieshaber-Bouyer, R.

10.1101/2024.07.26.605341 — bioinformatics — Posted on 2024-07-29

602 Protein Set Transformer: A protein-based genome language model to power high diversity viromics

Martin, C.; Gitter, A.; Anantharaman, K.

10.1101/2024.07.26.605391 — bioinformatics — Posted on 2024-07-29

603 Automated model discovery for textile structures:The unique mechanical signature of warp knitted fabrics

McCulloch, J. A.; Kuhl, E.

10.1101/2024.07.26.605392 — bioengineering — Posted on 2024-07-29

604 Influence of gonadal and chromosomal sex on the brain transcriptome in a mouse species with natural sex reversal

Heitzmann, L. D.; Saunders, P. A.; Perez, J.; Boursot, P.; Veyrunes, F.

10.1101/2024.07.26.605342 — evolutionary biology — Posted on 2024-07-29

605 Whole genome sequencing of 76 Mexican Indigenous reveals recent selection signatures linked to pathogens and diet adaptation.

Miron-Toruno, M. F.; Morett, E.; Aguilar-Ordonez, I.; Reynolds, A. W.

10.1101/2024.07.26.605344 — evolutionary biology — Posted on 2024-07-29

606 Simple, universal rules predict trophic interaction strengths

Coblentz, K. E.; Novak, M.; DeLong, J. P.

10.1101/2024.07.26.605380 — ecology — Posted on 2024-07-29

607 Comparing efficiencies of population control methods for responding to foreign animal disease threats in wild pigs

Snow, N. P.; Smith, B.; Lavelle, M.; Glow, M.; Chalkowski, K.; Leland, B.; Sherburne, S.; Fischer, J.; Kohen, K.; Cook, S.; Smith, H.; VerCauteren, K. C.; Miller, R.; Pepin, K.

10.1101/2024.07.26.605354 — ecology — Posted on 2024-07-29

608 Habitat use of rewilded horses and cattle as related to the functional and structural composition of plant communities in a European restored wetland ecosystem

Lovasz, L.; Korner-Nievergelt, F.; Amrhein, V.

10.1101/2024.07.27.605379 — ecology — Posted on 2024-07-29

609 Limitations in mitochondrial programming restrain the differentiation and maturation of human stem cell-derived β cells

Lietzke, A. C.; Bealer, E.; Crumley, K.; King, J.; Stendahl, A. M.; Zhu, J.; Pearson, G. L.; Levi-DAncona, E.; Henry-Kanarek, B.; Reck, E. C.; Arnipalli, M.; Sidarala, V.; Walker, E. M.; Pennathur, S.; Madsen, J. G. S.; Shea, L. D.; Soleimanpour, S. A.

10.1101/2024.07.26.605318 — developmental biology — Posted on 2024-07-29

610 Single cell autofluorescence imaging reveals immediate metabolic shifts of neutrophils with activation across biological systems

Datta, R.; Miskolci, V.; Gallego Lopez, G. M.; Britt, E.; Gillette, A.; Kralovec, A.; Giese, M. A.; Qian, T.; Fan, J.; Huttenlocher, A.; Skala, M. C.

10.1101/2024.07.26.605362 — immunology — Posted on 2024-07-29

611 Context-dependence of deterministic and nondeterministic contributions to closed-loop steering control

Egger, S. W.; Keemink, S. W.; Goldman, M. S.; Britten, K. H.

10.1101/2024.07.26.605325 — neuroscience — Posted on 2024-07-29

612 scPRINT: pre-training on 50 million cells allows robust gene network predictions

Kalfon, J.; Samaran, J.; Peyre, G.; Cantini, L.

10.1101/2024.07.29.605556 — bioinformatics — Posted on 2024-07-29

613 GRAViTy-V2: a grounded viral taxonomy application

Mayne, R. M.; Aiewsakun, P.; Turner, D.; Adriaenssens, E. M.; Simmonds, P.

10.1101/2024.07.26.605250 — bioinformatics — Posted on 2024-07-29

614 Structure of scavenger receptor SCARF1 and its interaction with lipoproteins

Wang, Y.; Xu, F.; Li, G.; Cheng, C.; Yu, B.; Zhang, Z.; Kong, D.; Chen, F.; Liu, Y.; Fang, Z.; Cao, L.; Yu, Y.; Gu, Y.; He, Y.

10.1101/2023.11.08.566208 — biophysics — Posted on 2024-07-29

615 Desmodium Volatiles in "Push-Pull" Agriculture and Protection Against the Fall Armyworm, Spodoptera frugiperda

Odermatt, D. M.; Chidawanyika, F.; Mutyambai, D. M.; Schmid, B.; Domeignoz Horta, L. A.; Tamiru, A.; Schuman, M. C.

10.1101/2024.07.24.604900 — ecology — Posted on 2024-07-29

616 Unravelling arthropod movement in natural landscapes: small-scale effects of body size and weather conditions

Logghe, G.; Taelman, C.; Van Hecke, F.; Batsleer, F.; Maes, D.; Bonte, D.

10.1101/2023.09.25.559245 — ecology — Posted on 2024-07-29

617 Community phylogenetic structure shapes pathogen outbreak potential in an epidemiological multi-host model

Toorians, M. E.; Smallegange, I.; Davies, J.

10.1101/2023.05.23.541907 — ecology — Posted on 2024-07-29

618 Analyzing the Involvement of Cholinesterases in the Immune Landscape of Lung Adenocarcinoma and Their Prognostic Values

Zhang, F.; Zhu, Z.; Guan, Y.; Li, M.; Pan, Z.; Wang, J.

10.1101/2024.05.09.593422 — molecular biology — Posted on 2024-07-29

619 Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility

Mowla, S.; Farahani, L.; Tharakan, T.; Davies, R.; Correia, G. D.; Lee, Y. S.; Kundu, S.; Khanjani, S.; Sindi, E.; Rai, R.; Regan, L.; Khalifa, D.; Henkel, R.; Minhas, S.; S. Dhillo, W.; Ben Nagi, J.; Bennett, P.; MacIntrye, D. A.; Jayasena, C. N.

10.1101/2024.02.18.580923 — microbiology — Posted on 2024-07-29

620 Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

Ecker, A.; Egas Santander, D.; Abdellah, M.; Blanco Alonso, J.; Bolanos-Puchet, S.; Chindemi, G.; Gowri Mariyappan, D. P.; Isbister, J. B.; King, J. G.; Kumbhar, P.; Magkanaris, I.; Muller, E. B.; Reimann, M. W.

10.1101/2023.08.07.552264 — neuroscience — Posted on 2024-07-29

621 Exploring the embodied mind: functional connectome fingerprinting of meditation expertise

Czajko, S.; Zorn, J.; Daumail, L.; Chetelat, G.; Margulies, D.; Lutz, A.

10.1101/2023.12.06.570128 — neuroscience — Posted on 2024-07-29

622 Identification of the potential function-specific sites in subunits of vertebrate neuronal nicotinic acetylcholine receptors

Zhu, Z.; Zhang, F.; Guan, Y.; Pan, Z.; Li, M.; Wang, J.

10.1101/2024.05.09.593419 — bioinformatics — Posted on 2024-07-29

623 Bifunctional probes reveal the rules of intracellular ether lipid transport

Böhlig, K.; Iglesias-Artola, J. M.; Lennartz, H. M.; Link, A. C.; Drobot, B.; Nadler, A.

10.1101/2024.07.26.605283 — cell biology — Posted on 2024-07-29

624 Opposing Sequential Biases in Direction and Time Reproduction: Influences of Task Relevance and Working Memory

Cheng, S.; Chen, S.; Shi, Z.

10.1101/2024.01.28.577640 — neuroscience — Posted on 2024-07-29

625 Embedding stochastic dynamics of the environment in spontaneous activity by prediction-based plasticity

Asabuki, T.; Clopath, C.

10.1101/2023.05.01.538909 — neuroscience — Posted on 2024-07-29

626 Predictive learning rules generate a cortical-like replay of probabilistic sensory experiences

Asabuki, T.; Fukai, T.

10.1101/2023.02.17.528958 — neuroscience — Posted on 2024-07-29

627 SpacerPlacer: Ancestral reconstruction of CRISPR arrays reveals the evolutionary dynamics of spacer deletions

Fehrenbach, A.; Mitrofanov, A.; Alkhnbashi, O. S.; Backofen, R.; Baumdicker, F.

10.1101/2024.02.20.581079 — bioinformatics — Posted on 2024-07-29

628 Guide assignment in single-cell CRISPR screens using crispat

Braunger, J. M.; Velten, B.

10.1101/2024.05.06.592692 — bioinformatics — Posted on 2024-07-29

629 FlowPacker: Protein side-chain packing with torsional flow matching

Lee, J. S.; Kim, P. M.

10.1101/2024.07.05.602280 — bioinformatics — Posted on 2024-07-29

630 Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism

Gilsbach, B. K.; Ho, F. Y.; Riebenbauer, B.; Zhang, X.; Guaitoli, G.; Kortholt, A.; Gloeckner, C. J.

10.1101/2023.07.31.549909 — biochemistry — Posted on 2024-07-29

631 Ridge and crossrib height of butterfly wing scales is a toolbox for structural color diversity

Finet, C.; Ruan, Q.; Bei, Y. Y.; Saranathan, V.; Monteiro, A.

10.1101/2024.03.28.585318 — evolutionary biology — Posted on 2024-07-29

632 Agent-Based Modelling shows that Operation of Fisher's Principle does not explain Zero Heritability in Human Offspring Sex Ratio

Harper, K.; Sidari, M. J.; Zietsch, B. P.

10.1101/2023.04.04.535652 — evolutionary biology — Posted on 2024-07-29

633 Family matters: Linking population growth, kin interactions, and African elephant social groups

Croll, J. C.; Caswell, H.

10.1101/2024.03.19.585476 — ecology — Posted on 2024-07-29

634 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data

Rehak Buckova, B.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.

10.1101/2023.06.09.544217 — neuroscience — Posted on 2024-07-29

635 Human V4 size predicts crowding distance

Kurzawski, J. W.; Qiu, B. S.; Majaj, N. J.; Benson, N. C.; Pelli, D.; Winawer, J.

10.1101/2024.04.03.587977 — neuroscience — Posted on 2024-07-29

636 AgRP1 modulates breeding season-dependent feeding behavior in female medaka

Tagui, Y.; Takeda, S.; Waida, H.; Kitahara, S.; Kimura, T.; Kanda, S.; Oka, Y.; Hayashi, Y.; Umatani, C.

10.1101/2024.07.10.602830 — neuroscience — Posted on 2024-07-29

637 The spatial layout of antagonistic brain regions is explicable based on geometric principles

Leech, R.; Braga, R.; Haydock, D.; Vowles, N.; Jefferies, E.; Bernhardt, B.; Turkheimer, F. E.; Alberti, F.; Margulies, D.; Sherwood, O.; Jones, E. J.; Smallwood, J.; Vasa, F.

10.1101/2024.06.17.599309 — neuroscience — Posted on 2024-07-29

638 Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1

Harold, R. L.; Tulsian, N. K.; Narasimamurthy, R.; Yaitanes, N.; Hernandez, M. G. A.; Lee, H.-W.; Crosby, P.; Tripathi, S.; Virshup, D. M.; Partch, C. L.

10.1101/2023.04.24.538174 — biochemistry — Posted on 2024-07-29

639 Single-nucleus and spatial transcriptomic analysis identified molecular features of neuronal heterogeneity and distinct glial responses in Parkinson's disease.

Yoo, S.; Lee, K.; Seo, J.; Choi, H.; Kim, S.-I.; Chang, J.; Shim, Y.-M.; Kim, J.; Won, J.-K.; Park, S.-H.

10.1101/2024.07.28.605055 — neuroscience — Posted on 2024-07-28

640 Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping

Zhang, D.; Rubio Rodriguez-Kirby, L. A.; Lin, Y.; Song, M.; Wang, L.; Wang, L.; Kanatani, S.; Jimenez-Beristain, T.; Dang, Y.; Zhong, M.; Kukanja, P.; Wang, S.; Chen, X. L.; Gao, F.; Wang, D.; Hang, X.; Lou, X.; Liu, Y.; Chen, J.; Sestan, N.; Uhlen, P.; Kriegstein, A.; Zhao, H.; Castelo-Branco, G.; Fan, R.

10.1101/2024.07.28.605493 — neuroscience — Posted on 2024-07-28

641 Characterization of Eye and Adnexal Tissues in Dogs and Wolves: A Histological and Lectin-Histochemical Approach

Diz Lopez, A.; Torres, M. V.; Martinez Gomez, F.; Lopez Beceiro, A. M.; Fidalgo, L.; Sanchez-Quinteiro, P.; Ortiz Leal, I.

10.1101/2024.07.26.605385 — neuroscience — Posted on 2024-07-28

642 The genetic architecture of resistance to flubendiamide insecticides in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae)

Amado, D.; Koch, E. L.; Cordeiro, E. M. G.; Araujo, W. A.; Garcia, A. A. F.; Heckel, D. G.; Montejo-Kovacevich, G.; North, H. L.; Correa, A. S.; Jiggins, C. D.; Omoto, C.

10.1101/2024.07.28.605483 — genetics — Posted on 2024-07-28

643 pH dependent direct sulfhydrylation pathway is required for pathogenesis of Mycobacterium tuberculosis

Nain, V. K.; Barik, V.; Pandey, M.; Pareek, M.; Sharma, T.; Pal, R.; Tyagi, S.; Bajpai, M.; Dwivedi, P.; Panda, B. N.; Kumar, Y.; Asthana, S.; Pandey, A. K.

10.1101/2024.07.28.605477 — microbiology — Posted on 2024-07-28

644 Lentivirus Transduced T Cell Lines Response to Pro-inflammatory and Antiviral Cytokines in the Presence of HIV

Ventocilla, K.; Miranda, D.; Sanchez, D. J.

10.1101/2024.07.27.605446 — immunology — Posted on 2024-07-28

645 Reassessment of body temperature and thermoregulation strategies in Mesozoic marine reptiles

Seon, N.; Vincent, P.; Delsett, L. L.; Poulallion, E.; Suan, G.; Lecuyer, C.; Roberts, A. J.; Fourel, F.; Charbonnier, S.; Amiot, R.

10.1101/2024.07.26.605303 — paleontology — Posted on 2024-07-28

646 Compaction-mediated segregation of partly replicated bacterial chromosome

Brahmachari, S.; Oliveira, A. B.; Mello, M. F.; Contessoto, V. G.; Onuchic, J. N.

10.1101/2024.07.27.604869 — biophysics — Posted on 2024-07-28

647 Single-sequence protein-RNA complex structure prediction by geometric attention-enabled pairing of biological language models

Roche, R.; Tarafder, S.; Bhattacharya, D.

10.1101/2024.07.27.605468 — bioinformatics — Posted on 2024-07-28

648 Multi-Modal CLIP-Informed Protein Editing

Yin, M.; Zhou, H.; Zhu, Y.; Lin, M.; Wu, Y.; Wu, J.; Xu, H.; Hsieh, C.-Y.; Hou, T.; Chen, J.; Wu, J.

10.1101/2024.07.28.605469 — bioinformatics — Posted on 2024-07-28

649 Active Learning-Assisted Directed Evolution

Yang, J.; Lal, R. G.; Bowden, J. C.; Astudillo, R.; Hameedi, M. A.; Kaur, S.; Hill, M.; Yue, Y.; Arnold, F. H.

10.1101/2024.07.27.605457 — bioengineering — Posted on 2024-07-28

650 Investigation of Intestinal Bacteria-binding Monoclonal Antibodies Derived from Rabbit Single B Cells

Anwar, K.; Kaneko, S.; Kawakita, I.; Adinegoro, D. S.; Kihara, M.; Ojima-Kato, T.; Nakano, H.

10.1101/2024.07.26.605397 — bioengineering — Posted on 2024-07-28

651 Lipid-directed covalent fluorescent labeling of plasma membranes for long-term imaging, barcoding and manipulation of cells

Aknine, N.; Pelletier, R.; Klymchenko, A. S.

10.1101/2024.07.28.605476 — biochemistry — Posted on 2024-07-28

652 Mapping the peripheral immune landscape of Parkinson's disease patients with single-cell sequencing

Moquin-Beaudry, G.; Andriamboavonjy, L.; Audet, S.; Hamilton, L.; Duquette, A.; Chouinard, S.; Panisset, M.; Tetreault, M.

10.1101/2024.07.26.605020 — genetics — Posted on 2024-07-28

653 Environmental versus litter traits as drivers of microbial decomposer functions

Stock, S. C.; Canessa, R.; van den Brink, L.; Cavieres, L. A.; Kappler, A.; Merino Guzman, C.; Saldana, A.; Scholten, T.; Schweiger, A. H.; Rehfeld, K.; Neidhardt, H.; Oelmann, Y.; Tielboerger, K.; Bader, M. Y.; Ehlers, T. A.; Dippold, M. A.

10.1101/2024.07.26.605152 — ecology — Posted on 2024-07-28

654 Does temperature, light or inter-individual variation explain feeding motivation in a tropical freshwater predator?

Brown, L. J.; Ioannou, C. C.

10.1101/2024.07.27.605438 — ecology — Posted on 2024-07-28

655 12-Lipoxygenase Inhibition Suppresses Islet Immune and Inflammatory Responses and Delays Autoimmune Diabetes in Human Gene Replacement Mice

Nargis, T.; Muralidharan, C.; Enriquez, J. R.; Wang, J. E.; Kaylan, K.; Chakraborty, A.; Pratuagntham, S.; Figatner, K.; Nelson, J. B.; May, S. C.; Nadler, J. L.; Boxer, M. B.; Maloney, D. J.; Tersey, S. A.; Mirmira, R. G.

10.1101/2024.07.28.604986 — molecular biology — Posted on 2024-07-28

656 TNF Superfamily Member 14 Drives Post-Influenza Depletion of Alveolar Macrophages Enabling Secondary Pneumococcal Pneumonia

Malainou, C.; Peteranderl, C.; Ferrero, M. R.; Vazquez-Armendariz, A. I.; Alexopoulos, I.; Better, J.; Estiri, M.; Schultheis, H.; Hoppe, J.; del Rio, M.-L.; Rodriguez-Barbosa, J. I.; Pfeffer, K.; Gunther, S.; Looso, M.; Gruber, A. D.; Vadasz, I.; Matt, U.; Herold, S.

10.1101/2024.07.28.605445 — molecular biology — Posted on 2024-07-28

657 Learning Random Numbers to Realize Appendable Memory System for Artificial Intelligence to Acquire New Knowledge after Deployment

Yamada, K. D.

10.1101/2023.05.25.542376 — neuroscience — Posted on 2024-07-28

658 Exploring the Single-Cell Dynamics of FOXM1 Under Cell Cycle Perturbations

Jawwad, T.; Kamkaew, M.; Phongkitkarun, K.; Chusorn, P.; Sampattavanich, S.

10.1101/2024.07.27.605093 — systems biology — Posted on 2024-07-28

659 Discovery and Quantification of Long-Range RNA Base Pairs in Coronavirus Genomes with SEARCH-MaP and SEISMIC-RNA

Allan, M. F.; Aruda, J.; Plung, J. S.; Grote, S. L.; Martin, Y. J.; de Lajarte, A. A.; Bathe, M.; Rouskin, S.

10.1101/2024.04.29.591762 — molecular biology — Posted on 2024-07-28

660 The acquisition of additional control over quorum sensing regulation buffers noise in microbial growth dynamics

Fondi, M.; Riccardi, C.; Di Patti, F.; Coscione, F.; Mengoni, A.; Perrin, E.

10.1101/2024.07.26.605310 — systems biology — Posted on 2024-07-28

661 The transcriptional response and genomic signature of metal tolerance in brown trout inhabiting metal-polluted rivers

Paris, J. R.; King, R. A.; Ferrer Obiol, J.; Shaw, S.; Lange, A.; Bourret, V.; Hamilton, P. B.; Rowe, D.; Laing, L. V.; Farbos, A.; Moore, K. A.; Urbina, M. A.; Catchen, J. M.; Wilson, R. W.; Bury, N. R.; Santos, E. M.; Stevens, J. R.

10.1101/2024.05.30.595956 — evolutionary biology — Posted on 2024-07-28

662 Causal Brain Network Evaluates Surgical Outcomes in Patients with Drug-Resistant Epilepsy

Wang, Y.; Lin, W.; Liu, M.

10.1101/2024.03.03.583165 — neuroscience — Posted on 2024-07-28

663 Pretrainable Geometric Graph Neural Network for Antibody Affinity Maturation

Cai, H.; Zhang, Z.; Wang, M.; Zhong, B.; Li, Q.; Zhong, Y.; Wu, Y.; Ying, T.; Tang, J.

10.1101/2023.08.10.552845 — bioinformatics — Posted on 2024-07-28

664 Phase-Restoring Subpixel Image Registration: Enhancing Motion Detection Performance in Fourier-domain Optical Coherence Tomography

Li, H.; Tan, B.; Pandiyan, V. P.; Barathi, V. A.; Sabesan, R.; Schmetterer, L.; Ling, T.

10.1101/2022.06.15.496241 — bioengineering — Posted on 2024-07-28

665 Transfer RNA acetylation regulates in vivo mammalian stress signaling

Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Amin, R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Hunter, K.; Gu, S.; Mock, B. A.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.

10.1101/2024.07.25.605208 — cell biology — Posted on 2024-07-28

666 Multiome Perturb-seq unlocks scalable discovery of integrated perturbation effects on the transcriptome and epigenome

Metzner, E.; Southard, K. M.; Norman, T. M.

10.1101/2024.07.26.605307 — systems biology — Posted on 2024-07-27

667 Deep-learning prediction of gene expression from personal genomes

Drusinsky, S.; Whalen, S.; Pollard, K. S.

10.1101/2024.07.27.605449 — genetics — Posted on 2024-07-27

668 AutoMorFi: Automated Whole-image Morphometry in Fiji/ImageJ for Diverse Image Analysis Needs

Bouadi, O.; Yao, C.; Zeng, J.; Beason, D.; Inda, N.; Malone, Z.; Yoshihara, J.; Manjally, A. V.; Johnson, C.; Cherry, J.; Chen, C.-Y.; Huang, T.-C.; Popovic, B.; Henley, M.; Liu, G.; Kharitonova, E.; Zeldich, E.; Aichelman, H.; Davies, S. W.; Walentek, P.; Tian, Y.; Man, H.; Ozsen, E.; Harder, K.; Gilmore, T. D.; Pitt, D.; Tay, T. L.

10.1101/2024.07.26.605357 — cell biology — Posted on 2024-07-27

669 A novel quinone biosynthetic pathway illuminates the evolution of aerobic metabolism

Elling, F. J.; Pierrel, F.; Chobert, S.-C.; Abby, S. S.; Evans, T. W.; Reveillard, A.; Pelosi, L.; Schnoebelen, J.; Hemingway, J. D.; Boumendjel, A.; Becker, K. W.; Blom, P.; Cordes, J.; Nathan, V.; Baymann, F.; Lucker, S.; Spieck, E.; Leadbetter, J. R.; Hinrichs, K.-U.; Summons, R. E.; Pearson, A.

10.1101/2024.07.27.605408 — microbiology — Posted on 2024-07-27

670 Cell-free expression of Nipah virus transmembrane proteins for proteoliposome vaccine design

Hu, V. T.; Ezzatpour, S.; Selivanovitch, E. T.; Carter, J.; Sahler, J.; Adeleke, R. A.; August, A.; Aguilar-Carreno, H.; Daniel, S.; Kamat, N. P.

10.1101/2024.07.26.605347 — synthetic biology — Posted on 2024-07-27

671 What NLR you recognizing? Predicted binding affinities- and energies may be used to identify novel NLR-effector interactions

Fick, A.; Fick, J. L. M.; Swart, V.; van den Berg, N.

10.1101/2024.07.26.605369 — plant biology — Posted on 2024-07-27

672 In-vitro Metabolite Identification for MEDI7219, an Oral GLP-1 Peptide, using LC-MS/MS with CID and EAD Fragmentation

Liu, K.; Huang, Y.; Wang, T.; Mu, R.; Rosenbaum, A. I.

10.1101/2024.07.26.605352 — pharmacology and toxicology — Posted on 2024-07-27

673 Preventing evolutionary rescue in cancer

Patil, S.; Ahmed, A.; Viossat, Y.; Noble, R. J.

10.1101/2023.11.22.568336 — cancer biology — Posted on 2024-07-27

674 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging

Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.

10.1101/2023.12.05.570058 — cancer biology — Posted on 2024-07-27

675 Mechano-metabolism of metastatic breast cancer cells in 2D and 3D microenvironments

Jaganathan, A.; Toth, J. M.; Chen, X.; Basir, R.; Pieuchot, L.; Shen, Y.; Reinhart-King, C. A.; Shenoy, V. B.

10.1101/2024.04.30.591879 — biophysics — Posted on 2024-07-27

676 GW: ultra-fast chromosome-scale visualisation of genomics data

Cleal, K.; Kearsey, A.; Baird, D. M.

10.1101/2024.07.26.605272 — bioinformatics — Posted on 2024-07-27

677 A fluorescent biosensor for the visualization of agmatine

Kröger, P.; Stiel, A. C.; Stüven, B.; Shanmugaratnam, S.; Schoch, S.; Wachten, D.; Höcker, B.

10.1101/2024.07.27.605435 — biochemistry — Posted on 2024-07-27

678 p53 protein abundance is a therapeutic window across TP53 mutant cancers and is targetable with proximity inducing small molecules

Sadagopan, A.; Garaffo, N.; Chang, H.-J.; Schreiber, S. L.; Meyerson, M.; Gibson, W. J.

10.1101/2024.07.27.605429 — biochemistry — Posted on 2024-07-27

679 Gαs-specific structural elements attenuate interactions with RGS proteins

Higazy-Mreih, S.; LeGouill, C.; Bouvier, M.; Kosloff, M.

10.1101/2024.07.27.605439 — biochemistry — Posted on 2024-07-27

680 An anomalous 3'-terminal phosphorothioated mismatch bypass activity and its application as a binary molecular switch

Kumar, S.; Gariya, H. S.; Sharma, C.; Parveen, S.; Nair, V. K.; Sengupta, M.; Ghosh, S.

10.1101/2024.07.27.605420 — biochemistry — Posted on 2024-07-27

681 Comparative Genomic Analysis of Campylobacter rectus and Closely Related Species

Hughes Lago, C. A.; Blackburn, D.; Kinder Pavlicek, M.; Threadgill, D. S.

10.1101/2024.07.26.605372 — genomics — Posted on 2024-07-27

682 Sex Dimorphism in Expression of Immune Response Genes in Drosophila

Khan, M. M.; Graze, R. M.

10.1101/2024.07.27.605461 — genetics — Posted on 2024-07-27

683 CAnDI: a new tool to investigate conflict in homologous gene trees and explain convergent trait evolution

Robertson, H. M.; Walker, J. F.; Moyroud, E.

10.1101/2023.11.18.567661 — evolutionary biology — Posted on 2024-07-27

684 Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue

Zhou, P.; Kessinger, C. W.; Gu, F.; King, J. S.; Davenport, A.; Wang, G.; Negron, S. G.; Deplancke, B.; Pu, W. T.; Lin, Z.

10.1101/2024.07.09.602788 — developmental biology — Posted on 2024-07-27

685 Characterisation of human hair follicle development

Sudderick, Z. R.; Glover, J. D.; Batho-Samblas, C.; Shih, B. B.-J.; Headon, D. J.

10.1101/2024.07.26.605346 — developmental biology — Posted on 2024-07-27

686 Transfer RNA acetylation regulates in vivo mammalian stress signaling

Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Mock, B. A.; Gu, S.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.

10.1101/2024.07.25.605208 — cell biology — Posted on 2024-07-27

687 Development of antisense tools to study Bodo saltans and its intracellular symbiont

Ahrar, M.; Glenn, L.; Held, M.; Jackson, A.; Kus, K.; Hurst, G. D.; Chrostek, E.

10.1101/2024.07.27.605423 — molecular biology — Posted on 2024-07-27

688 Histone H2B Monoubiquitylation Regulates Elongation-to-Termination Transition in RNA Polymerase II Transcription

Parua, P. K.; Bandyopadhyay, T.; Basu, B.

10.1101/2024.07.27.605434 — molecular biology — Posted on 2024-07-27

689 Concatemer Assisted Stoichiometry Analysis (CASA): a targeted mass spectrometry method for protein quantification

Cai, J.; Quan, Y.; Zhang, C. Y.; Wang, Z.; Hinshaw, S. M.; Zhou, H.; Suhandynata, R. T.

10.1101/2024.07.26.605382 — molecular biology — Posted on 2024-07-27

690 Polyamines sustain epithelial regeneration in aged intestines by modulating protein homeostasis

Minetti, A.; Omrani, O.; Brenner, C.; Allies, G.; Imada, S.; Roesler, J.; Khawaled, S.; Cansiz, F.; Meckelmann, S.; Gebert, N.; Heinze, I.; Lu, J.; Spengler, K.; Rasa, M.; Heller, R.; Yilmaz, O. H.; Tasdogan, A.; Neri, F.; Ori, A.

10.1101/2024.07.26.605278 — molecular biology — Posted on 2024-07-27

691 Linalool's Multifaceted Antimicrobial Potential: Unveiling its Antimicrobial Efficacy and Immunomodulatory Role Against Saprolegnia parasitica

Tao, T.; Zhong, W.; Tang, P.; Dai, R.; Guo, J.; Gao, Z.

10.1101/2024.06.24.600497 — microbiology — Posted on 2024-07-27

692 Urea assimilation and oxidation supports the activity of a phylogenetically diverse microbial community in the dark ocean

Arandia-Gorostidi, N.; Jaffe, A. L.; Parada, A. E.; Kapili, B. J.; Casciotti, K. L.; Salcedo, R. S. R.; Baumas, C. M. J.; Dekas, A. E.

10.1101/2024.07.26.605319 — microbiology — Posted on 2024-07-27

693 Conserved perception of host and non-host signals via the a-pheromone receptor Ste3 in Colletotrichum graminicola

Rudolph, A. Y.; Schunke, C.; Nordzieke, D. E.

10.1101/2024.07.27.605416 — microbiology — Posted on 2024-07-27

694 Investigation of the threonine metabolism of Echinococcus multilocularis: the threonine dehydrogenase as a potential drug target in alveolar echinococcosis

Kaethner, M.; Zumstein, P.; Preza, M.; Bartetzko, A.; Grossenbacher, P.; Lochner, M.; Schuerch, S.; Regnault, C.; Ramirez, D. V.; Lundstroem-Stadelmann, B.

10.1101/2024.07.27.605433 — microbiology — Posted on 2024-07-27

695 Gut microbiota metabolically mediate intestinal helminth infection in Zebrafish

Hammer, A. J.; Gaulke, C. A.; Garcia - Jaramillo, M.; Leong, C.; Morre, J. T.; Sieler, M. J.; Stevens, J. F.; Jiang, Y.; Maier, C. S.; Kent, M. L.; Sharpton, T. J.

10.1101/2024.07.26.605207 — microbiology — Posted on 2024-07-27

696 Chemically-informed coarse-graining of electrostatic forces in charge-richbiomolecular condensates

Tejedor, A. R.; Aguirre Gonzalez, A.; Maristany, M. J.; Chew, P. Y.; Rusell, K.; Ramirez, J.; Espinosa, J. R.; Collepardo-Guevara, R.

10.1101/2024.07.26.605370 — biophysics — Posted on 2024-07-27

697 Nucleotide dependency analysis of DNA language models reveals genomic functional elements

Tomaz da Silva, P.; Karollus, A.; Hingerl, J.; Galindez, G.; Wagner, N.; Hernandez-Alias, X.; Incarnato, D.; Gagneur, J.

10.1101/2024.07.27.605418 — genomics — Posted on 2024-07-27

698 Reconstitution of chromatin reorganization during mammalian oocyte development

Wang, J.; Li, W.; Guo, J.; Xu, X.; Ge, L.; Li, B.; So, C.

10.1101/2024.07.27.605426 — developmental biology — Posted on 2024-07-27

699 Physical modeling of embryonic transcriptomes identifies collective modes of gene expression

Skinner, D.; Lemaire, P.; Mani, M.

10.1101/2024.07.26.605398 — developmental biology — Posted on 2024-07-27

700 Heat Shock alters the distribution and in vivo interaction of major nuclear structural proteins - Lamin B with DNA Topoisomerase II, and with nucleic acids

Rowinska, M.; Tomczak, A.; Jablonska, J.; Machowska, M.; Piekarowicz, K.; Rzepecki, R.

10.1101/2024.02.28.582469 — cell biology — Posted on 2024-07-27

701 A replicable and generalizable neuroimaging-based indicator of pain sensitivity across individuals

Zhang, L.-B.; Lu, X.; Zhang, H.; Wei, Z.; Kong, Y.; Tu, Y.; Iannetti, G.; Hu, L.

10.1101/2024.06.08.597884 — neuroscience — Posted on 2024-07-27

702 The role of binocular disparity and attention in the neural representation of multiple moving stimuli in the visual cortex

Chakrala, A. S.; Xiao, J.; Huang, X.

10.1101/2023.06.25.546480 — neuroscience — Posted on 2024-07-27

703 Prevalence of GIT nematodes and associated risk factors of exotic chickens in selected farm of poultry in and around Ambo, Ethiopia

Temesgen, A. B.; Wassie, Z. G.; Abebe, S.

10.1101/2024.07.02.601802 — pathology — Posted on 2024-07-27

704 Limiting the impact of protein leakage in single-cell proteomics

Leduc, A.; Xu, Y.; Shipkovenska, G.; Dou, Z.; Slavov, N.

10.1101/2024.07.26.605378 — molecular biology — Posted on 2024-07-27

705 The intersection of endocrine signaling and neuroimmune communication regulates neonatal nociception

Fadaka, A. O.; Dourson, A. J.; Hofmann, M. C.; Gupta, P.; Raut, N. G. R.; Jankowski, M. P.

10.1101/2024.07.26.605393 — neuroscience — Posted on 2024-07-27

706 SGLT2 inhibitors activate pantothenate kinase in the human heart

Forelli, N.; Eaton, D.; Patel, J.; Bowman, C.; Kawakami, R.; Kuzetsnov, I.; Li, K.; Brady, C.; Bedi, K.; Yang, Y.; Koya, K.; Megill, E.; Kantner, D.; Smith, L.; Bowman, G.; Snyder, N.; Edwards, J.; Margulies, K.; Arany, Z.

10.1101/2024.07.26.605401 — biochemistry — Posted on 2024-07-27

707 Proteomic Profiling Reveals Age-Related Changes in Transporter Proteins in the Human Blood-Brain Barrier

Zhou, X.; Azimi, M.; Handin, N.; Riselli, A.; Vora, B.; Chun, E.; Yee, S. W.; Artursson, P.; Giacomini, K. M.

10.1101/2024.07.26.604313 — developmental biology — Posted on 2024-07-27

708 Peri-mitochondrial actin filaments inhibit Parkin assembly via disruption of ER-mitochondrial contact

Fung, T. S.; Ghosh, A.; Tigano, M.; Higgs, H. N.; Chakrabarti, R.

10.1101/2024.07.26.605389 — cell biology — Posted on 2024-07-27

709 Evidence of centromeric histone 3 chaperone involved in DNA damage repair pathway

Agarwal, P.; Ghosh, S. K.

10.1101/2024.07.26.605363 — cell biology — Posted on 2024-07-27

710 Visual cues for moisture perception of facial skin: Enhancing high-frequency components of skin lightness increases perceived dryness

Hasegawa, Y.; Tamura, H.; Kanematsu, T.; Yamada, Y.; Ishiguro, Y.; Nakauchi, S.; Minami, T.

10.1101/2024.07.16.603839 — neuroscience — Posted on 2024-07-27

711 Aberrant FGF signaling promotes granule neuron precursor expansion in SHH subgroup infantile medulloblastoma

Yabut, O.; Gomez, H.; Arela, J.; Castillo, J. G.; Ngo, T.; Pleasure, S. J.

10.1101/2021.06.23.449636 — cancer biology — Posted on 2024-07-27

712 GW: ultra-fast chromosome-scale visualisation of genomics data

Cleal, K.; Kearsey, A.; Baird, D. M.

10.1101/2024.07.26.605272 — bioinformatics — Posted on 2024-07-27

713 Principles of ion binding to RNA inferred from the analysis of a 1.55 A resolution bacterial ribosome structure - Part I: Mg2+

Filip, L.; Henning-Knechtel, A.; Kirmizialtin, S.; Ennifar, E.; Auffinger, P.

10.1101/2024.04.07.588377 — molecular biology — Posted on 2024-07-27

714 Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System

Wang, Z.-H.; An, Y.; Zhao, T.; Pei, T.-T.; Wang, D. Y.; Liang, X.; Qin, W.; Dong, T.

10.1101/2024.07.24.605002 — microbiology — Posted on 2024-07-27

715 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.

Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.; Phillips, A.; Cardone, M.

10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-07-27

716 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery

Umansky, T.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.

10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-07-27

717 Vasopressin 1a receptor antagonist disrupts male-male affiliative relationships formed by triadic cohabitation in large-billed crows

Seguchi, A.; Izawa, E.-I.

10.1101/2024.02.01.578519 — animal behavior and cognition — Posted on 2024-07-27

718 The genetic basis of the black pupae phenotype in tephritid fruit flies

Paulo, D. F.; Nguyen, T. N. M.; Ward, C. M.; Corpuz, R. L.; Kauwe, A. N.; Rendon, P.; Ruano, R. E. Y.; Cardoso, A. A. S.; Gouvi, G.; Fung, E.; Crisp, P.; Okada, A.; Choo, A.; Stauffer, C.; Bourtzis, K.; Sim, S. B.; Baxter, S. W.; Geib, S. M.

10.1101/2024.06.07.597636 — genomics — Posted on 2024-07-27

719 How resource abundance and stochasticity affect organisms' range sizes

Mezzini, S.; Fleming, C.; Medici, P.; Noonan, M. J.

10.1101/2023.11.03.565563 — ecology — Posted on 2024-07-27

720 Growth parameters of the clupeids Limnothrissa miodon and Stolothrissa tanganicae in northern Lake Tanganyika (Bujumbura sub-basin)

N'Sibula, M. T.; Gordo-Vilaseca, C.; Milec, L. J. M.; Patel, D. M.; Kankonda, A. B.; Micha, J.-C.; Sarvala, J.; Raeymaekers, J. A. M.

10.1101/2024.03.16.584994 — ecology — Posted on 2024-07-27

721 Non-floral scent sources of orchid bees: observations and significance

Henske, J.; De Dijn, B.; Eltz, T.

10.1101/2024.07.22.604569 — ecology — Posted on 2024-07-27

722 Long-range chemical signalling in vivo is regulated by mechanical signals

Pillai, E. K.; Mukherjee, S.; Gampl, N.; McGinn, R. J.; Mooslehner, K. A.; Becker, J.; Thompson, A. J.; Franze, K.

10.1101/2024.02.15.580459 — developmental biology — Posted on 2024-07-27

723 Modelling genetic risk of β-cell dysfunction in human induced pluripotent stem cells from patients carrying the MTNR1B risk variant.

Singh, T.; Kalamajski, S.; Cunha, J. P. M. C. M.; Hladkou, S.; Roberts, F.; Gheibi, S.; Soltanian, A.; Yektay Farahmand, K.; Ekstrom, O.; Mamidi, A.; Franks, P. W.; Rosengren, A.; Semb, H.; Mulder, H.; Fex, M.

10.1101/2024.07.19.603674 — cell biology — Posted on 2024-07-27

724 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds

Vasan, R.; Ferrante, A.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.

10.1101/2024.07.25.605164 — cell biology — Posted on 2024-07-27

725 Maize diterpenoid sensing via Ste3 a-pheromone receptor and rapid germination of Colletotrichum graminicola oval conidia facilitating root infection

Rudolph, A. Y.; Schunke, C.; Sasse, C.; Antelo, L.; Gerke, J.; Braus, G.; Poeggeler, S.; Nordzieke, D. E.

10.1101/2024.04.05.588234 — microbiology — Posted on 2024-07-27

726 Adolescent Alcohol Exposure Promotes Mechanical Allodynia and Alters Synaptic Function at Inputs from the Basolateral Amgydala to the Prelimbic Cortex

Obray, J. D.; Wilkes, E. T.; Scofield, M. D.; Chandler, L. J.

10.1101/2024.06.17.599360 — neuroscience — Posted on 2024-07-27

727 Reduced monitoring of task performance is an effective biomarker of autism

Zuk, N. J.; Weiss, Y.; Akrami, A.; Ahissar, M.

10.1101/2024.07.23.604831 — neuroscience — Posted on 2024-07-27

728 Environmental context sculpts spatial and temporal visual processing in thalamus

Peelman, K.; Haider, B.

10.1101/2024.07.26.605345 — neuroscience — Posted on 2024-07-27

729 Effects of transient, persistent, and resurgent sodium currents on excitability and spike regularity in vestibular ganglion neurons

Baeza-Loya, S.; Eatock, R. A.

10.1101/2023.11.28.569044 — neuroscience — Posted on 2024-07-27

730 Imputing Single-Cell Protein Abundance in Multiplex Tissue Imaging

Kirchgaessner, R.; Watson, C.; Creason, A. L.; Keutler, K.; Goecks, J.

10.1101/2023.12.05.570058 — cancer biology — Posted on 2024-07-27

731 Single-molecule analysis reveals TDG exhibits multiple modes of linear diffusion to process 5-formylcytosine.

Schnable, B. L.; Schaich, M. A.; Roginskaya, V.; Leary, L. P.; Weaver, T. M.; Freudenthal, B. D.; Drohat, A. C.; Van Houten, B.

10.1101/2023.10.04.560925 — biophysics — Posted on 2024-07-27

732 Hierarchical Gaussian process models explore the dark meltome of thermal proteome profiling experiments.

Le Sueur, C.; Rattray, M.; Savitski, M.

10.1101/2023.10.26.564129 — bioinformatics — Posted on 2024-07-27

733 Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Opa1 and Mfn2

Boopathy, S.; Luce, B. E.; Lugo, C. M.; Hakim, P.; McDonald, J. L.; Kim, H. L.; Ponce, J.; Ueberheide, B.; Chao, L. H.

10.1101/2023.12.29.573615 — biochemistry — Posted on 2024-07-27

734 Statistical learning beyond words in human neonates

Flo, A.; Benjamin, L.; Palu, M.; Dehaene-Lambertz, G.

10.1101/2024.07.26.605295 — neuroscience — Posted on 2024-07-26

735 Efficient internalization of poly(benzyl malate) and poly(ethylene glycol)-b-poly(benzyl malate) copolymer based nanoparticles by human hepatic HepaRG cells and macrophages : Impact of nanoparticle functionalization by GBVA10-9 peptide on cell uptake.

NAHAS, H.; SABA, S.; METLEJ, P.; RIBAULT, C.; VENE, E.; LEPAREUR, N.; CAMMAS-MARION, S.; LOYER, P.

10.1101/2024.07.26.605135 — cell biology — Posted on 2024-07-26

736 Utility of cellular imaging modality in subcellular spatial transcriptomic profiling of tumor tissues

Song, X.; Yu, X.; Moran-Segura, C.; Grass, G. D.; Li, R.; Wang, X.

10.1101/2024.07.25.605221 — bioinformatics — Posted on 2024-07-26

737 Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

Klemm, J.; Van Hazel, C.; Harris, R. E.

10.1101/2024.07.26.605350 — genetics — Posted on 2024-07-26

738 A multicellular actin star network underpins epithelial organization and connectivity

Barai, A.; Soleilhac, M.; Xi, W.; Lin, S.-Z.; Karnat, M.; Bazellieres, E.; Richelme, S.; Berrebi, D.; Ruemmele, F.; Thery, M.; Rupprecht, J.-F.; Delacour, D.

10.1101/2024.07.26.605277 — cell biology — Posted on 2024-07-26

739 FZD2 inhibits YAP and prevents cell cycle reentry in adult murine cardiomyocytes

Bisson, J. A.; Quijada, P. J.; Wang, Y. T.; Lighthouse, J. K.; Helt, J. C.; Kim, E.; Morrisey, E. E.; Brookes, P. S.; Small, E. M.; Cohen, E. D.

10.1101/2024.07.26.605158 — cell biology — Posted on 2024-07-26

740 Modelling molecular differences in the innate immune system responses of chickens and ducks to highly pathogenic avian influenza virus

Wood, T.; An, G.; Bryant, C. E.; Ferguson, B. J.

10.1101/2024.07.26.605270 — immunology — Posted on 2024-07-26

741 Genome-Wide Association Study of Metabolic Traits in the Duckweed Spirodela polyrhiza

Hoefer, M.; Wink, S.; Schaefer, M.; Wang, Y.; Xu, S.

10.1101/2024.07.26.605148 — plant biology — Posted on 2024-07-26

742 Gz Enhanced Signal Transduction assaY (GZESTY) for GPCR deorphanization

Franchini, L.; Porter, J. J.; Lueck, J. D.; Orlandi, C.

10.1101/2024.07.26.605282 — pharmacology and toxicology — Posted on 2024-07-26

743 Fully Automated MRI-based Analysis of the Locus Coeruleus in Aging and Alzheimer's Disease Dementia using ELSI-Net

Dünnwald, M.; Krohn, F.; Sciarra, A.; Sarkar, M.; Schneider, A.; Fliessbach, K.; Kimmich, O.; Jessen, F.; Rostamzadeh, A.; Glanz, W.; Incesoy, E.; Teipel, S.; Kilimann, I.; Goerss, D.; Spottke, A.; Brustkern, J.; Heneka, M.; Brosseron, F.; Lüsebrink, F.; Hämmerer, D.; Düzel, E.; Tönnies, K.; Oeltze-Jafra, S.; Betts, M. J.

10.1101/2024.07.26.605356 — bioinformatics — Posted on 2024-07-26

744 Segmentation and Feature Extraction of Fingernail Plate and Lunula Based on Deep Learning

Fan, Y.; You, M.; Ge, J.; Zhai, G.; Wang, S.

10.1101/2024.07.26.605289 — bioinformatics — Posted on 2024-07-26

745 Mechanisms Ensuring Fidelity of Family X DNA Polymerases in Programmed DNA rearrangements in Paramecium tetraurelia

Nourisson, A.; Missoury, S.; Haouz, A.; Delarue, M.

10.1101/2024.07.26.605286 — biochemistry — Posted on 2024-07-26

746 Signatures of selective sweeps in continuous-space populations

Chotai, M.; Wei, X.; Messer, P. W.

10.1101/2024.07.26.605365 — evolutionary biology — Posted on 2024-07-26

747 Decoding protein phosphorylation during oocyte meiotic divisions using phosphoproteomics

Peshkin, L.; Daldello, E. M.; Van Itallie, E. S.; Sonnett, M.; Kreuzer, J.; Haas, W.; Kirschner, M. W.; Jessus, C.

10.1101/2024.07.26.605364 — developmental biology — Posted on 2024-07-26

748 Cdhr1a and pcdh15b link photoreceptor outer segments with inner segment calyceal processes revealing a potential mechanism for cone-rod dystrophy.

Patel, M. K.; Piedade, W. P.; Famulski, J.

10.1101/2024.07.26.605360 — developmental biology — Posted on 2024-07-26

749 Bifunctional probes reveal the rules of intracellular ether lipid transport

Böhlig, K.; Iglesias-Artola, J. M.; Lennartz, H. M.; Link, A. C.; Drobot, B.; Nadler, A.

10.1101/2024.07.26.605283 — cell biology — Posted on 2024-07-26

750 Reticulon dependent ER-phagy mediates adaptation to heat stress in Caenorhabditis elegans

Scarcelli, V.; Serot, C.; Pouget, A.; Largeau, C.; Sagot, A.; El-Hachimi, K.; Dupuy, D.; Culetto, E.; Lefebvre, C.; Legouis, R.

10.1101/2024.07.26.605287 — cell biology — Posted on 2024-07-26

751 Equine piroplasmosis in different geographical areas in France: prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi

Jouglin, M.; Bonsergent, C.; de la Cotte, N.; Mege, M.; Bizon, C.; Courouce, A.; Lallemand, E.; Leblond, A.; Lemonnier, L.; Leroux, A.; Marano, I.; Muzard, A.; Quere, E.; Toussaint, M.; Agoulon, A.; Malandrin, L.

10.1101/2024.07.26.605244 — microbiology — Posted on 2024-07-26

752 CD6 Regulates CD4 T Follicular Helper Cell Differentiation and Humoral Immunity During Murine Coronavirus Infection

Cardani Boulton, A.; Lin, F.; Bergmann, C. C.

10.1101/2024.07.26.605237 — immunology — Posted on 2024-07-26

753 Epithelial memory after respiratory viral infection results in long-lasting enhancement of antigen presentation

Janas, P. P.; T'Jonck, W.; Burgess, M.; Chauche, C.; Vermeren, M.; Lucas, C.; Bain, C. C.; Illingworth, R. S.; Roberts, E. W.; McSorley, H. J.; Schwarze, J.

10.1101/2024.07.26.605255 — immunology — Posted on 2024-07-26

754 An essential role for glial cells in postingestive nutrient sensing

Kulshrestha, D.; Koch, C. R.; Khalilov, M.; Schirmeier, S.

10.1101/2024.07.26.605306 — neuroscience — Posted on 2024-07-26

755 Episodic rhythmicity is generated by a distributed neural network in the developing mammalian spinal cord

Milla-Cruz, J. J.; Lognon, A. P.; Tran, M. A.; Di Vito, S. A.; Loer, C.; Shonak, A.; Broadhead, M. J.; Miles, G. B.; Sharples, S. A.; Whelan, P. J.

10.1101/2024.07.26.605187 — neuroscience — Posted on 2024-07-26

756 MitoMAMMAL: a genome scale model of mammalian mitochondria predicts cardiac and BAT metabolism

Chapman, S.; Brunet, T.; Mourier, A.; Habermann, B. H.

10.1101/2024.07.26.605281 — systems biology — Posted on 2024-07-26

757 Differential biotransformation ability may alter fish biodiversity in polluted waters

Franco, M. E.; Hollender, J.; Schirmer, K.

10.1101/2024.07.26.605280 — pharmacology and toxicology — Posted on 2024-07-26

758 Horizontal transfer of nuclear DNA in transmissible cancer

Gori, K. C.; Baez-Ortega, A.; Strakova, A.; Stammnitz, M. R.; Wang, J.; Chan, J.; Hughes, K.; Belkhir, S.; Hammel, M.; Moralli, D.; Bancroft, J.; Drydale, E.; Allum, K. M.; Brignone, M. V.; Corrigan, A. M.; de Castro, K. F.; Donelan, E. M.; Faramade, I. A.; Hayes, A.; Ignatenko, N.; Karmacharya, R.; Koenig, D.; Lanza-Perea, M.; Lopez Quintana, A. M.; Meyer, M.; Neunzig, W.; Pedraza-Ordonez, F.; Phuentshok, Y.; Phuntsho, K.; Ramirez-Ante, J. C.; Reece, J. F.; Schmeling, S. K.; Singh, S.; Tapia Martinez, L. J.; Taulescu, M.; Thapa, S.; Thapa, S.; van der Wel, M. G.; Wehrle-Martinez, A. S.; Strat

10.1101/2024.07.26.604742 — cancer biology — Posted on 2024-07-26

759 Development of a new flippase-dependent mouse model for red fluorescence-based isolation of KrasG12D oncogene-expressing tumor cells

Hrckulak, D.; Krausova, M.; Onhajzer, J.; Stastna, M.; Kriz, V.; Janeckova, L.; Korinek, V.

10.1101/2024.07.26.605291 — cancer biology — Posted on 2024-07-26

760 A fast and simple approach to k-mer decomposition

Kunzmann, P.

10.1101/2024.07.26.605312 — bioinformatics — Posted on 2024-07-26

761 Conformational dynamics and asymmetry in multimodal inhibition of membrane-bound pyrophosphatases

Vidilaseris, K.; Ma, Y.; Hardman, K.; Johansson, N. G.; De Castro Ribeiro, O. M.; Yli-Kauhaluoma, J.; Xhaard, H.; Jeuken, L. J. C.; Brookfield, A.; Bowen, A.; Liu, J.; -, ; Shah, A.; Pliotas, C.

10.1101/2024.07.26.605302 — biochemistry — Posted on 2024-07-26

762 Expanding the substrate selectivity of the fimsbactin biosynthetic adenylation domain, FbsH

Ahmed, S. F.; Balutowski, A.; Yang, J.; Wencewicz, T. A.; Gulick, A. M.

10.1101/2024.07.26.605314 — biochemistry — Posted on 2024-07-26

763 The zebrafish (Danio rerio) snoRNAome

Hamar, R.; Varga, M.

10.1101/2024.07.26.605292 — genomics — Posted on 2024-07-26

764 Multiple variants of IncF plasmid alleles discovered within single bacterial cells challenge previous assumptions

Ruzickova, M.; Palkovicova, J.; Papousek, I.; Cummins, M. L.; Djordjevic, S. P.; Dolejska, M.

10.1101/2024.07.26.605309 — genomics — Posted on 2024-07-26

765 Environmentally-mediated selection parallels population divergence across a chimpanzee subspecies contact zone

Mitchell, M. W.; Alexander, W.; Mitchell, D. V.; Freedman, A. H.; Dordel, J.; Harrigan, R. J.; Sacan, A.; Kentatchime, F.; Featherstone, B. S.; Abwe, E. E.; Sesink Clee, P. R.; Abwe, A. E.; Locatelli, S.; Morgan, B. J.; Fosso, B.; Fotso, R.; Tishkoff, S. A.; Eichler, E. E.; Anthony, N. M.; Smith, T. B.; Gonder, M. K.

10.1101/2024.07.26.605171 — genomics — Posted on 2024-07-26

766 CO-OPTION OF NECK MUSCLES SUPPORTED THE VERTEBRATE WATER-TO-LAND TRANSITION

Heude, E.; Dutel, H.; Sanchez-Garrido, F.; Prummel, K. D.; Lalonde, R.; Lam, F.; Mosimann, C.; Herrel, A.; Tajbakhsh, S.

10.1101/2024.07.26.605297 — evolutionary biology — Posted on 2024-07-26

767 PLK-1 regulates MEX-1 polarization in the C. elegans zygote

Kim, A. J.; Miller, S. I.; Greiner, E. C.; Kettenbach, A. N.; Griffin, E. E.

10.1101/2024.07.26.605193 — developmental biology — Posted on 2024-07-26

768 Global coordination of protrusive forces in migrating immune cells

Reis-Rodrigues, P.; Canigova, N.; Avellaneda, M. J.; Gaertner, F.; Vaahtomeri, K.; Riedl, M.; Merrin, J.; Hauschild, R.; Fukui, Y.; Garcia, A. J.; Sixt, M.

10.1101/2024.07.26.605242 — cell biology — Posted on 2024-07-26

769 Expansion of the genomic and functional diversity of global ocean giant viruses

Minch, B.; Moniruzzaman, M.

10.1101/2024.07.26.605358 — microbiology — Posted on 2024-07-26

770 Quantifying synthetic bacterial community composition with flow cytometry: efficacy in mock communities and challenges in co-cultures

Mermans, F.; Chatzigiannidou, I.; Teughels, W.; Boon, N.

10.1101/2024.07.26.605308 — microbiology — Posted on 2024-07-26

771 Patterns of neural activity in prelimbic cortex neurons correlate with attentional behavior in the rodent continuous performance test

Miranda-Barrientos, J. A.; Adiraju, S.; Rehg, J. J.; Hallock, H.; Li, Y.; Carr, G.; Martinowich, K.

10.1101/2024.07.26.605300 — neuroscience — Posted on 2024-07-26

772 Partial redundancy buffers deleterious effects of mutating DNA methyltransferase 1-1 (MET1-1) in polyploid wheat

Burrows, S.; Dorussen, D.; Crudgington, J.; Di Santolo, G.; Simmonds, J.; Catoni, M.; Borrill, P.

10.1101/2024.07.26.605257 — plant biology — Posted on 2024-07-26

773 PRAME expression in melanoma is negatively regulated by TET2-mediated DNA hydroxymethylation

Fang, R.; Vallius, T.; Zhang, A.; Van Cura, D.; Alicandri, F.; Fischer, G.; Draper, E.; Xu, S.; Pelletier, R.; Katsyv, I.; Sorger, P. K.; Murphy, G. F.; Lian, C. G.

10.1101/2024.07.26.605293 — cancer biology — Posted on 2024-07-26

774 Gamma Approximation of Stratified Truncated Exact test (GASTE-test) & Application

Wendling, A.; Galiez, C.

10.1101/2024.07.26.605317 — bioinformatics — Posted on 2024-07-26

775 A non-autonomous protein quality control mechanism targeting tau aggregate propagation

Bluemke, A.; Hagemeier, B.; Ripkens, K.; Schulze, N.; Strzala, M.; Koci, M.; Kaschani, F.; Kaiser, M.; Erkelenz, M.; Schluecker, S.; Merdanovic, M.; Poepsel, S.; Hellerschmied, D.; Burston, S.; Ehrmann, M.

10.1101/2024.07.26.605305 — biochemistry — Posted on 2024-07-26

776 Coupling proximity biotinylation with genomic targeting to characterize locus-specific changes in chromatin environments

Kougnassoukou Tchara, P.-E.; Loehr, J.; Lambert, J.-P.

10.1101/2024.07.26.605321 — biochemistry — Posted on 2024-07-26

777 Phylogenomics resolves the relationship and the evolutionary history of planthoppers (Insecta: Hemiptera: Fulgoromorpha)

Deng, J.; Stroinski, A.; Szwedo, J.; Ghanavi, H. R.; Yapar, E.; Franco, D. C.; Prus-Frankowska, M.; Michalik, A.; Wahlberg, N.; Lukasik, P.

10.1101/2024.07.26.605304 — evolutionary biology — Posted on 2024-07-26

778 Extensive haplotype diversity in a butterfly colour pattern supergene is fuelled by incomplete recombination suppression

De-Kayne, R.; Gordon, I. J.; Terblanche, R. F.; Collins, S.; Omufwoko, K. S.; Martins, D. J.; Martin, S. H.

10.1101/2024.07.26.605145 — evolutionary biology — Posted on 2024-07-26

779 On the use of kinship and familiarity associated social information in mediating Drosophila melanogaster oviposition decisions

Rakosy, E.; Talagala, S.; Long, T. A. F.

10.1101/2024.07.26.604403 — evolutionary biology — Posted on 2024-07-26

780 Dynamics of influenza transmission in vampire bats revealed by longitudinal monitoring and a large-scale anthropogenic perturbation

Griffiths, M. E.; Broos, A.; Morales, J.; Tu, I.-T.; Bergner, L.; Behdenna, A.; Valderrama, W.; Tello, C.; Carrera, J. E.; Recuenco, S.; Streicker, D. G.; Viana, M.

10.1101/2024.07.26.605290 — ecology — Posted on 2024-07-26

781 Avian-restrict Salmonella transition to endemicity is accompanied by localized resistome adaptation

Jia, C.; Huang, C.; Zhou, H.; Zhou, X.; Wang, Z.; Siddique, A.; Kang, X.; Cao, Q.; Huang, Y.; He, F.; Li, Y.; Yue, M.

10.1101/2024.07.26.605275 — microbiology — Posted on 2024-07-26

782 Early life microbial succession in the gut follows common patterns in humans across the globe

Fahur Bottino, G.; Bonham, K. S.; Patel, F.; McCann, S.; Zieff, M.; Naspolini, N.; Ho, D.; Portlock, T.; Joos, R.; Midani, F. S.; Schüroff, P.; Das, A.; Shennon, I.; Wilson, B. C.; O'Sullivan, J. M.; Britton, R. A.; Murray, D. M.; Kiely, M. E.; Taddei, C. R.; Beltrao-Braga, P. C.; Campos, A. C.; Polanczyk, G. V.; Huttenhower, C.; Donald, K. A.; Klepac-Ceraj, V.

10.1101/2024.07.25.605223 — microbiology — Posted on 2024-07-26

783 A new regulator of sporulation sheds light on spore morphogenesis and ballistospory in mushroom-forming fungi

Hou, Z.; Meretenyi, Z.; Yang, Y.; Zhang, Y.; Csernetics, A.; Balint, B.; Hegedus, B.; Foldi, C.; Wu, H.; Kristoffy, Z.; Abraham, E.; Miklovics, N.; Viragh, M.; Liu, X.-B.; Zsibrita, N.; Lipinszki, Z.; Karcagi, I.; Gao, W.; Nagy, L. G.

10.1101/2024.07.26.604922 — microbiology — Posted on 2024-07-26

784 Different CMV-specific effector T cell subtypes are associated with age, CMV serostatus, and increased systolic blood pressure

Roesner, L. M.; Traidl, S.; Bosnjak, B.; Huehn, J.; Forster, R.; Werfel, T.

10.1101/2024.07.26.605265 — immunology — Posted on 2024-07-26

785 Rab5 Overcomes CAR T Cell Dysfunction Induced by Tumor-Mediated CAR Capture

Gu, M.; Carvalho, E.; Read, K.; Nardo Padron, D.; Riley, J. L.

10.1101/2024.07.26.605334 — immunology — Posted on 2024-07-26

786 Activating Cognitive Processes in Human Cortex at Multiple Low-Frequency Bands

Gong, Z.-Q.; Zuo, X.-N.

10.1101/2024.07.26.605234 — neuroscience — Posted on 2024-07-26

787 A finite set of content-free pointers in visual working memory: MEG evidence

Yu, X.; Lau, E.

10.1101/2024.07.26.605172 — neuroscience — Posted on 2024-07-26

788 Epileptiform activity and seizure risk follow long-term non-linear attractor dynamics

Rosch, R. E.; Scheid, B.; Davis, K. A.; Litt, B.; Ashourvan, A.

10.1101/2024.07.26.605279 — neuroscience — Posted on 2024-07-26

789 Successful retrieval is its own reward

Smith, D. E.; Long, N. M.

10.1101/2024.07.26.605274 — neuroscience — Posted on 2024-07-26

790 Contrast-dependent response modulation in convolutional neural networks captures behavioral and neural signatures of visual adaptation

Brands, A. M.; Oz, Z.; Vuksic, N.; Ortiz, P.; Groen, I. I. A.

10.1101/2024.07.26.605075 — neuroscience — Posted on 2024-07-26

791 An aging-sensitive compensatory secretory phospholipase that confers neuroprotection and cognitive resilience

Vicidomini, C.; Goode, T. D.; McAvoy, K.; Yu, R.; Beveridge, C.; Iyer, S.; Victor, M. B.; Leary, N.; Evans, L.; Steinbaugh, M. J. B.; Lai, Z. W.; Lyon, M. C.; Silvestre, M. R. F. S.; Bonilla, G.; Sadreyev, R. I.; Walther, T. C.; Sui, S. H.; Saido, T.; Yamamoto, K.; Murakami, M.; Tsai, L.-H.; Chopra, G.; Sahay, A.

10.1101/2024.07.26.605338 — neuroscience — Posted on 2024-07-26

792 A second X chromosome improves cognition in aging male and female mice

Marino, F.; Wang, D.; Merrihew, G. E.; MacCoss, M. J.; Dubal, D.

10.1101/2024.07.26.605328 — neuroscience — Posted on 2024-07-26

793 Structured flexibility in recurrent neural networks via neuromodulation

Costacurta, J. C.; Bhandarkar, S.; Zoltowski, D. M.; Linderman, S. W.

10.1101/2024.07.26.605315 — neuroscience — Posted on 2024-07-26

794 Engineering anti-amyloid antibodies with transferrin receptor targeting improves safety and brain biodistribution

Pizzo, M. E.; Plowey, E. D.; Khoury, N.; Kwan, W.; Abettan, J.; DeVos, S. L.; Discenza, C. B.; Earr, T.; Joy, D.; Lye-Barthel, M.; Roche, E.; Chan, D.; Dugas, J. C.; Gadkar, K.; Meisner, R.; Sebalusky, J.; Silva Amaral, A. C.; Becerra, I.; Chau, R.; Chow, J.; Clemens, A. J.; Dennis, M. S.; Duque, J.; Fusaro, L.; Getz, J. A.; Kariolis, M. S.; Kim, D. J.; Leung, A. W.-S.; Nguyen, H. N.; Thomsen, E. R.; Sanchez, P. E.; Shan, L.; Silverman, A. P.; Solanoy, H.; Tong, R.; Calvert, M. E. K.; Watts, R. J.; Thorne, R. G.; Weinreb, P. H.; Walsh, D. M.; Lewcock, J. W.; Bussiere, T.; Zuchero, Y. J. Y.

10.1101/2024.07.26.604664 — neuroscience — Posted on 2024-07-26

795 Olfactory projection neuron rewiring in the brain of an ecological specialist

Duerr, B. R.; Bertolini, E.; Takagi, S.; Pascual, J.; Abuin, L.; Lucarelli, G.; Benton, R.; Auer, T. O.

10.1101/2024.07.26.605288 — neuroscience — Posted on 2024-07-26

796 Environmental context sculpts spatial and temporal visual processing in thalamus

Haider, B.; Peelman, K.

10.1101/2024.07.26.605345 — neuroscience — Posted on 2024-07-26

797 In vivo analysis of the relationship between CP26 and qE-type NPQ via higher-order Arabidopsis cp26 mutants

Kromdijk, J.; Walter, J.; Patel-Tupper, D.; Lam, L.; Ma, A.; Taylor, G.; Fleming, G.; Niyogi, K. K.

10.1101/2024.07.26.605339 — plant biology — Posted on 2024-07-26

798 Adaptive resistance to FLT3 inhibitors is potentiated by ROS-driven DNA repair signalling

Staudt, D. E.; Germon, Z. P.; Mannan, A.; McLachlan, T.; Murray, H. C.; Duchatel, R. J.; Thomas, B. C.; Beitaki, T.; McEwen, H. P.; Persson, M. L.; Calvert, L.; Findlay, I. J.; Jackson, E. R.; Smith, N. D.; Skerrett-Byrne, D. A.; Mossman, D.; Nixon, B.; De Iullis, G.; Douglas, A. M.; Enjeti, A. K.; Sillar, J. R.; Chamberlain, J.; Alvaro, F.; Wei, A. H.; Connerty, P.; Verrills, N.; Dun, M. D.

10.1101/2024.07.26.605229 — cancer biology — Posted on 2024-07-26

799 Insight into the Interaction between Neuronal Calcium Sensors and Insulin

Peddapuvala, S. U. K.; Sharma, Y.; Sankeshi, V.

10.1101/2024.07.26.605271 — biophysics — Posted on 2024-07-26

800 Competitive modulation of Kv1.2 gating by LMAN2 and Slc7a5

Das, D.; Lamothe, S. M.; Wong, A. A.; Baronas, V. A.; Kurata, H. T.

10.1101/2024.07.25.605230 — biophysics — Posted on 2024-07-26

801 Activation of the influenza B M2 proton channel (BM2)

Yue, Z.; Wu, J.; Teng, D.; Wang, Z.; Voth, G. A.

10.1101/2024.07.26.605324 — biophysics — Posted on 2024-07-26

802 Ligand induced receptor multimerization achieves the specificity enhancement of kinetic proofreading without associated costs

Kirby, D.; Zilman, A.

10.1101/2024.07.26.605371 — biophysics — Posted on 2024-07-26

803 GW: ultra-fast chromosome-scale visualisation of genomics data

Baird, D. M.; Kearsey, A.; Cleal, K.

10.1101/2024.07.26.605272 — bioinformatics — Posted on 2024-07-26

804 Learning cell fate landscapes from spatial transcriptomics using Fused Gromov-Wasserstein

Huizing, G.-J.; Peyre, G.; Cantini, L.

10.1101/2024.07.26.605241 — bioinformatics — Posted on 2024-07-26

805 ConsensuSV-ONT - a modern method for accurate structural variant calling

Pietryga, A.; Chilinski, M.; Gadakh, S.; Plewczynski, D.

10.1101/2024.07.26.605267 — bioinformatics — Posted on 2024-07-26

806 Multiscale Molecular Modelling of Chromatin with MultiMM: From Nucleosomes to the Whole Genome

Korsak, S.; Banecki, K.; Plewczynski, D.

10.1101/2024.07.26.605260 — bioinformatics — Posted on 2024-07-26

807 A benchmark of muscle models to length changes great and small

Millard, M.; Stutzig, N.; Fehr, J.; Siebert, T.

10.1101/2024.07.26.605117 — bioengineering — Posted on 2024-07-26

808 Plasma proteome profiling for AKI biomarker candidates associated with first-line ART in people living with HIV in South Africa

Mokoena, R. J.; Nabeemeeah, F.; Variava, E.; Fanucchi, S.; Martinson, N.; Govender, I. S.; Naicker, P.

10.1101/2024.07.26.605118 — biochemistry — Posted on 2024-07-26

809 Optimized reporters for multiplexed detection of transcription factor activity

Trauernicht, M.; Filipovska, T.; Rastogi, C.; van Steensel, B.

10.1101/2024.07.26.605239 — genomics — Posted on 2024-07-26

810 Indirect genetic effects increase the heritable variation available to selection and are largest for behaviours: a meta-analysis

Santostefano, F.; Moiron, M.; Sanchez-Tojar, A.; Fisher, D. N.

10.1101/2024.05.17.594196 — evolutionary biology — Posted on 2024-07-26

811 Interindividual vocal tract diversity influences the phonetic diversification of spoken languages

Moran, S.; Danner, T.; Ponce de Leon, M.; Zollikofer, C.

10.1101/2024.07.26.605254 — evolutionary biology — Posted on 2024-07-26

812 The optimal clutch size revisited: separating individual quality from the parental survival costs of reproduction

Winder, L. A.; Simons, M. J. P.; Burke, T.

10.1101/2022.05.30.493969 — evolutionary biology — Posted on 2024-07-26

813 Emissions of climate-altering species from open vegetation fires in the Mediterranean region

Hundal, R. A.; Annadate, S.; Cesari, R.; Collalti, A.; Maione, M.; Cristofanelli, P.

10.1101/2024.07.26.605246 — ecology — Posted on 2024-07-26

814 Asynchronous mouse embryo polarization leads to heterogeneity in cell fate specification

Lamba, A.; Zhu, M.; Meglicki, M.; Czukiewska, S.; Balasubramaniam, L.; Hadas, R.; Weishaupt, N.; Patel, E.; Kavanagh, Y. H.; Wang, R.; Jing, N.; Zernicka-Goetz, M.

10.1101/2024.07.26.605266 — developmental biology — Posted on 2024-07-26

815 Identification of a novel myosin antigen activating CD8+ T cells in C57BL/6 mice

Richter, L.; Bauer, M.; Bernsen, C.; Vogel, E.; Mahmud, Z.; Saliba, A.-E.; Schulz, R.; Frantz, S.; Ashour, D.; Ramos, G. C.

10.1101/2024.07.26.605251 — immunology — Posted on 2024-07-26

816 Specific pre-plasma cell states and local proliferation at the dark zone - medulla interface characterize germinal center-derived plasma cell differentiation in lymph node

Binet, L.; Dong, C.; Attaf, N.; Gil, L.; Fallet, M.; Boudier, T.; Escaliere, B.; Chasson, L.; Siret, C.; van de Pavert, S. A.; Navarro, J.-M.; Milpied, P.

10.1101/2024.07.26.605240 — immunology — Posted on 2024-07-26

817 PD-1 negatively regulates helper T cell differentiation into Th2

Tajima, M.; Ikuta, N.; Nakajima, Y.; Suzuki, K.; Tokumaru, Y.; Li, P.; Kiyonari, H.; Honjo, T.; Ohta, A.

10.1101/2024.07.26.605269 — immunology — Posted on 2024-07-26

818 DOCK8 regulates a mechanosensitive actin redistribution that maintains immune cell cohesion and protects the nucleus during migration

Shen, C.; Postat, J.; Cerf, A.; Merino, M.; Bhagrath, A.; Patel, D.; Luo, V.; Abu-Thuraia, A.; Schneider, C.; Sharma, A.; Suh, W.-K.; Ehrlicher, A.; Cote, J.-F.; Mandl, J. N.

10.1101/2024.07.26.605273 — immunology — Posted on 2024-07-26

819 A single microRNA miR-195 rescues the arrested B cell development induced by EBF1 deficiency

Miyatake, Y.; Ikawa, T.; Yanagiya, R.; Kotaki, R.; Kameda, K.; Nasu, R. K.; Okuyama, K.; Hirano, K.-i.; Hosokawa, H.; Hozumi, K.; Ohtsuka, M.; Kisikawa, T.; Shibata, C.; Otsuka, M.; Maruyama, R.; Ando, K.; Kurosaki, T.; Kawamoto, H.; Kotani, A.

10.1101/2024.07.26.605276 — immunology — Posted on 2024-07-26

820 CD11b suppresses TLR7-driven inflammatory signaling to protect against lupus nephritis

Li, X.; Villanueva, V.; Jimenez, V.; Nguyen, B.; Chauhan, N. R.; Khan, S. Q.; Alzahrani, K.; Wei, H.; Cimbaluk, D. J.; Wei, D. C.; Jolly, M.; Lopez-Rodiguez, D.; Pineda, S. B.; Barbosa, A.; Faridi, H. M.; Reiser, J.; Niewold, T. B.; Gupta, V.

10.1101/2024.07.26.605143 — immunology — Posted on 2024-07-26

821 Spatial (Mis)match Between EEG and fMRI Signal Patterns Revealed by Spatio-Spectral Source-Space EEG Decomposition

Jiricek, S.; Koudelka, V.; Mantini, D.; Marecek, R.; Hlinka, J.

10.1101/2024.07.26.605087 — neuroscience — Posted on 2024-07-26

822 Guided by touch: Tactile Cues in Hand Movement Control

Vlachou, M. E.; Legros, J.; Sellin, C.; Paleressompoulle, D.; Massi, F.; Simoneau, M.; Mouchnino, L.; Blouin, J.

10.1101/2024.07.26.605248 — neuroscience — Posted on 2024-07-26

823 Role of somatic HCN in epileptiform activity in subicular neurons

Alfred, M.; Sikdar, S. K.

10.1101/2024.07.26.604395 — neuroscience — Posted on 2024-07-26

824 Sensorimotor restriction affects sleep-related motor memory consolidation through altered slow oscillation-spindle coupling.

Conessa, A.; Leger, D.; Boutin, A.

10.1101/2024.07.26.605262 — neuroscience — Posted on 2024-07-26

825 Dose-related Mutagenic and Clastogenic Effects of Benzofluoranthene in Mouse Somatic Tissues Detected by Duplex Sequencing and the Micronucleus Assay

Schuster, D. M.; LeBlanc, D. P. M.; Zhou, G.; Meier, M. J.; Dodge, A. E.; White, P. A.; Long, A. S.; Williams, A.; Hobbs, C.; Diesing, A.; Smith-Roe, S. L.; Salk, J. J.; Marchetti, F.; Yauk, C. L.

10.1101/2024.07.26.605228 — pharmacology and toxicology — Posted on 2024-07-26

826 Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

Crombie, T. A.; Rajaei, M.; Saxena, A. S.; Johnson, L. M.; Saber, S.; Tanny, R. E.; Ponciano, J. M.; Andersen, E. C.; Zhou, J.; Baer, C. F.

10.1101/2024.05.08.593038 — evolutionary biology — Posted on 2024-07-26

827 Weathering the storm for love: Mate searching behaviour of wild males of the Sydney funnel-web spider (Atrax robustus)

Creak, C. N.; Muirhead, H.; Bonduriansky, R.; Kasumovic, M.; Buzatto, B.

10.1101/2024.07.23.604707 — animal behavior and cognition — Posted on 2024-07-26

828 Genomic Epidemiology of Monkeypox Virus During the 2022 Outbreak in New York City

Akther, S.; Su, M.; Wang, J. C.; Amin, H.; Taki, F.; De La Cruz, N.; Chowdhury, M.; Clabby, T.; Kopping, E.; Ruiz, V. E.; Leelawong, M.; Latash, J.; Johnson, K.; Baumgartner, J.; Wong, M.; Olsen, A.; Fowler, R. C.; Pekar, J. C.; Havens, J. L.; Vasylyeva, T. I.; Wertheim, J. O.; Hughes, S.; Omoregie, E.

10.1101/2024.07.23.604793 — genomics — Posted on 2024-07-26

829 Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity

Zhang, S.; Roeder, R. G.

10.1101/2024.07.25.605008 — molecular biology — Posted on 2024-07-26

830 The valine-arginine dipeptide repeat protein encoded by mammalian telomeric RNA appears highly expressed in mitosis and may repress global translation

Griffith, J. D.; Willcox, S.; Mills, C. A.; Herring, L. E.; Anton, E.; Cho, S.-j.; Lee, H.; meyer, C.; Al-Turki, T.; Mantri, V.

10.1101/2024.07.24.604971 — molecular biology — Posted on 2024-07-26

831 Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System

Wang, Z.-H.; An, Y.; Zhao, T.; Pei, T.-T.; Wang, D. Y.; Liang, X.; Qin, W.; Dong, T.

10.1101/2024.07.24.605002 — microbiology — Posted on 2024-07-26

832 The divergence of DHN-derived melanin pathways in Metarhizium robertsii

Xie, L.; Liu, Y.; Zhang, Y.; Chen, K.; Yue, Q.; Wang, C.; Dun, B.; Xu, Y.; Zhang, L.

10.1101/2024.07.25.605210 — microbiology — Posted on 2024-07-26

833 CD103+ Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis

Carter, H.; Medina Costa, R.; Bame, M.; Gilchrist, T.; Emch, C.; Adams, T.; Linderholm, A.; Oldham, J. M.; Noth, I.; Kaminski, N.; Moore, B. B.; Gurczynski, S. J.

10.1101/2024.03.15.584457 — immunology — Posted on 2024-07-26

834 EFMouse: a Matlab toolbox to model electric fields in the mouse brain

Sanchez-Romero, R.; Akyuz, S.; Krekelberg, B.

10.1101/2024.07.25.605227 — neuroscience — Posted on 2024-07-26

835 History-dependent spiking facilitates efficient encoding of polarization angles in neurons of the central complex

Rother, L.; Stöckl, A. L.; Pfeiffer, K.

10.1101/2024.07.25.605186 — neuroscience — Posted on 2024-07-26

836 An Orthogonal T7 Replisome for Continuous Hypermutation and Accelerated Evolution in E. coli

Diercks, C. S.; Sondermann, P.; Rong, C.; Dik, D. A.; Gillis, T. G.; Ban, Y.; Schultz, P. G.

10.1101/2024.07.25.605042 — synthetic biology — Posted on 2024-07-26

837 Development and Assessment of a Sustainable PhD Internship Program Supporting Diverse Biomedical Career Outcomes

Brandt, P. D.; Whittington, D.; Wood, K. D.; Holmquist, C. E.; Nogueira, A. T.; Gaines, C. H.; Brennwald, P. J.; Layton, R. L.

10.1101/2023.07.13.548912 — scientific communication and education — Posted on 2024-07-26

838 New integrative vectors increase Agrobacterium rhizogenes transformation and help characterise roles for soybean GmTML gene family members

Su, H.; Zhang, M.; Grundy, E. B.; Ferguson, B. J.

10.1101/2024.07.25.605222 — plant biology — Posted on 2024-07-26

839 Alleviation of salt stress in strawberries by hydrogen-rich water: physiological, transcriptomic and metabolomic responses

Wang, R.; Chu, S.; Zhang, D.; Zhang, X.; Chi, Y.; Ma, X.; Chen, X.; Yang, H.; Ding, W.; Zhao, T.; Ren, Y.; Yang, X.; Zhou, P.

10.1101/2024.07.25.605184 — physiology — Posted on 2024-07-26

840 Chromatin Remodeling by the Histone Methyltransferase SETD2 Drives Lipotoxic Injury in Cardiometabolic Heart Failure with Preserved Ejection Fraction

Ambrosini, S.; Costantino, S.; Mohammed, S. A.; Gorica, E.; Herwig, M.; van Heerebeek, L.; Mengozzi, A.; Karsai, G.; Hornemann, T.; Dzemali, O.; Ruschitzka, F.; Hamdani, N.; Paneni, F.

10.1101/2024.07.25.605217 — physiology — Posted on 2024-07-26

841 Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

Takao, S.; Morell, V.; Uni, M.; Slavit, A.; Rha, S.; Cheng, S.; Schmalbrock, L. K.; Brown, F. C.; Calabuig, S. B.-; Koche, R.; Velten, L.; Kentsis, A.

10.1101/2022.09.22.509005 — cancer biology — Posted on 2024-07-26

842 Structural Dynamics of LDL Receptor Interactions with E498A and R499G Variants of PCSK9

Azhar, N. A. A.; Jusoh, S. A.; Nawawi, H. M.; Chua, Y. A.

10.1101/2024.07.25.605225 — biophysics — Posted on 2024-07-26

843 ChromBERT: Uncovering Chromatin State Motifs in the Human Genome Using a BERT-based Approach

Lee, S.; Lin, C.; Chen, C.-Y.; Nakato, R.

10.1101/2024.07.25.605219 — bioinformatics — Posted on 2024-07-26

844 Evaluating the effects of archaic protein-altering variants in living human adults

Molz, B.; Lana Alberro, M.; Eising, E.; Schijven, D.; Alagöz, G.; Francks, C.; Fisher, S. E.

10.1101/2024.07.05.602242 — genetics — Posted on 2024-07-26

845 Trapping Devices of Carnivorous Fungus Arthrobotrys oligospora Can Isolate Heat-Triggered Excess Irons

Zhou, J.; Wu, Q.; Wu, L.; Yan, J.; Cheng, Q.; Wang, D.; Niu, X.

10.1101/2024.07.25.605209 — evolutionary biology — Posted on 2024-07-26

846 Heterochrony in orthodenticle expression is associated with ommatidial size variation between Drosophila species

Torres-Oliva, M.; Buchberger, E.; Buffry, A. D.; Kittelmann, M.; Guerrero, G.; Sumner-Rooney, L.; Gaspar, P. M. C.; Bullinger, G. C.; Figueras Jimenez, J.; Casares, F.; Arif, S.; Nunes, D. S.; Posnien, N.; McGregor, A. P.; Almudi, I.

10.1101/2021.03.17.435774 — evolutionary biology — Posted on 2024-07-26

847 Imperfect symmetry facilitated the evolution of specificity and high-order stoichiometry in vertebrate hemoglobin

Cortez-Romero, C. R.; Lyu, J.; Pillai, A.; Laganowsky, A.; Thornton, J. W.

10.1101/2024.07.24.604985 — evolutionary biology — Posted on 2024-07-26

848 Partitioning changes in ecosystem productivity by effects of species interactions in biodiversity experiments

Tao, J.; Nock, C.; Searle, E. B.; Huang, s.; Man, R.; Yang, H.; Freschet, G.; Violle, C.; Zheng, J.

10.1101/2024.03.30.587418 — ecology — Posted on 2024-07-26

849 The collective application of shorebird tracking data to conservation

Harrison, A.-L.; Stenzel, C.; Anderson, A.; Howell, J.; Lanctot, R. B.; Aikens, M.; Aldabe, J.; Berigan, L. A.; Bety, J.; Blomberg, E.; Bosi de Almeida, J.; Boyce, A. J.; Bradley, D. W.; Brown, S.; Carlisle, J.; Cheskey, E.; Christie, K.; Christin, S.; Clay, R.; Dayer, A.; Deppe, J. L.; English, W.; Flemming, S. A.; Gilg, O.; Gilroy, C.; Heath, S.; Hill, J. M.; Hipfner, J. M.; Johnson, J. A.; Johnson, L.; Kempenaers, B.; Knaga, P.; Kwon, E.; Lagasse, B. J.; Lamarre, J.-F.; Latty, C.; Leandri-Breton, D.-J.; Lecomte, N.; Loring, P.; McGuire, R.; Moorhead, S.; Navedo, J. G.; Newstead, D.; Nol, E.

10.1101/2024.01.30.576574 — ecology — Posted on 2024-07-26

850 Multi-species genome-wide CRISPR screens identify GPX4 as a conserved suppressor of cold-induced cell death

Lam, B.; Kajderowicz, K. M.; Keys, H. R.; Roessler, J. M.; Frenkel, E. M.; Kirkland, A.; Bisht, P.; El-Brolosy, M. A.; Jaenisch, R.; Bell, G. W.; Weissman, J. S.; Griffith, E. C.; Hrvatin, S.

10.1101/2024.07.25.605098 — cell biology — Posted on 2024-07-26

851 Mobile Integrons Encode Phage Defense Systems

Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ortiz-Miravalles, L.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.

10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-26

852 A mechanistic step in the genesis of secondary chromosomes from plasmids

Fournes, F.; Campos, M.; Cury, J.; Schiavon, C.; Pages, C.; Touchon, M.; Rocha, E. P. C.; Rousseau, P.; Cornet, F.

10.1101/2024.04.05.588136 — microbiology — Posted on 2024-07-26

853 Enhancing Statistical Power While Maintaining Small Sample Sizes in Behavioral Neuroscience Experiments Evaluating Success Rates

Theo, D.; Thevenet, M.; Garcia, S.; Lightning, A.; Didier, A.; Mandairon, N.; Kuczewski, N.

10.1101/2024.07.25.605060 — neuroscience — Posted on 2024-07-26

854 Uncertainty-modulated prediction errors in cortical microcircuits

Wilmes, K. A.; Petrovici, M. A.; Sachidhanandam, S.; Senn, W.

10.1101/2023.05.11.540393 — neuroscience — Posted on 2024-07-26

855 Lack of Single Amino Acids Transcriptionally Remodels Sensory Systems to Enhance the Intake of Protein and Microbiota

Ezra, G.; Henriques, S. F.; Muench, D.; Francisco, A. P.; Baltazar, C.; Elias, A. P.; Deplancke, B.; Ribeiro, C.

10.1101/2024.07.23.604616 — neuroscience — Posted on 2024-07-26

856 Genetic variance in the murine defensin locus modulates glucose homeostasis

Masson, S. W. W.; Simpson, R. C.; Cutler, H. B.; Carlos, P. W.; Marian, O. C.; Potter, M.; Madsen, S.; Cooke, K. C.; Craw, N. R.; Fuller, O. K.; Harney, D. J.; Larance, M.; Cooney, G. J.; Morahan, G.; Shanahan, E. R.; Hodgkins, C.; Payne, R. J.; Stöckli, J.; James, D. E.

10.1101/2024.07.25.605202 — systems biology — Posted on 2024-07-26

857 Molecular mimicry of a pathogen virulence target by a plant immune receptor

Gomez De La Cruz, D.; Zdrzałek, R.; Banfield, M. J.; Talbot, N. J.; Moscou, M. J.

10.1101/2024.07.26.605320 — plant biology — Posted on 2024-07-26

858 Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin (ELGA) reveal functional IP3 receptors

Calvo, B.; Torres-Vidal, P.; Delrio, A.; Rodriguez, C.; Aulestia, F.; Rojo-Ruiz, J.; McVeigh, B. M.; Moiseenkova-Bell, V.; Yule, D. I.; Garcia-Sancho, J.; Patel, S.; Alonso, M. T.

10.1101/2023.07.11.547422 — physiology — Posted on 2024-07-26

859 Efficient Generation of Protein Pockets with PocketGen

Zhang, Z.; Shen, W.; Liu, Q.; Zitnik, M.

10.1101/2024.02.25.581968 — bioinformatics — Posted on 2024-07-26

860 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma

Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.

10.1101/2023.07.12.548656 — bioengineering — Posted on 2024-07-26

861 Luminescence-based complementation assay to assess target engagement and cell permeability of glycolate oxidase (HAO1) inhibitors.

Mackinnon, S. R.; Zarganes-Tzitzikas, T.; Adams, C. J.; Brennan, P. E.; Yue, W. W.

10.1101/2024.06.26.600887 — biochemistry — Posted on 2024-07-26

862 TIPP_plastid: A User-Friendly Tool for De Novo Assembly of Organellar Genomes with HiFi Data

Xian, W.; Bezrukov, I.; Bao, Z.; Vorbrugg, S.; Gautam, A.; Weigel, D.

10.1101/2024.01.29.577798 — genomics — Posted on 2024-07-26

863 Evolution of Virulence in Emerging Epidemics: From Theory to Experimental Evolution and Back

Benhamou, W.; Blanquart, F.; Choisy, M.; Berngruber, T. W.; Choquet, R.; Gandon, S.

10.1101/2024.03.13.584824 — evolutionary biology — Posted on 2024-07-26

864 Negative impact of mild arid conditions in natural rodent populations revealed using markers of physiological condition in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-07-26

865 Microbes with higher metabolic independence are enriched in human gut microbiomes under stress

Veseli, I.; Chen, Y. T.; Schechter, M. S.; Vanni, C.; Fogarty, E. C.; Watson, A. R.; Jabri, B. A.; Blekhman, R.; Willis, A. D.; Yu, M. K.; Fernandez-Guerra, A.; Fussel, J.; Eren, A. M.

10.1101/2023.05.10.540289 — microbiology — Posted on 2024-07-26

866 Cross-modal interaction of Alpha Activity does not reflect inhibition of early sensory processing: A frequency tagging study using EEG and MEG

Brickwedde, M.; Limachya, R.; Markiewicz, R.; Sutton, E.; Postzich, C.; Shapiro, K.; Jensen, O.; Mazaheri, A.

10.1101/2022.04.19.488727 — neuroscience — Posted on 2024-07-26

867 Grasp Orientation in Ambiguous Settings is Sensitive to Prior Object Motion

Maffitt, N. J.; Cairns, E. G.; Wozna, J.; Soteropoulos, D. S.; Kraskov, A.

10.1101/2023.11.20.567846 — neuroscience — Posted on 2024-07-26

868 Moderate-term dimethyl fumarate treatment reduces pathology of dystrophic skeletal and cardiac muscle in a mouse model

Kourakis, S.; Timpani, C. A.; Bagaric, R. M.; Qi, B.; Ali, B. A.; Boyer, R.; Spiesberger, G.; Kandhari, N.; Peterson, A. L.; Debrincat, D.; Yates, T. J.; Yan, X.; Kuang, J.; de Haan, J. B.; Stupka, N.; Nijagal, B.; Deveson-Lucas, D.; Fischer, D.; Rybalka, E.

10.1101/2024.07.13.601627 — pathology — Posted on 2024-07-26

869 Transfer RNA acetylation regulates in vivo mammalian stress signaling

Thalalla Gamage, S.; Khoogar, R.; Howpay Manage, S. A.; Crawford, M. C.; Georgeson, J.; Polevoda, B. V.; Sanders, C.; Lee, K. A.; Nance, K. D.; Iyer, V.; Kustanovich, A.; Perez, M.; Thu, C. T.; Nance, S. R.; Miller, C. N.; Holewinski, R. J.; Meyer, T.; Koparde, V.; Yang, A.; Jailwala, P.; Nguyen, J. T.; Andresson, T.; Mock, B. A.; Gu, S.; Edmondson, E. F.; Difilippantonio, S.; Chari, R.; Schwartz, S.; O'Connell, M. R.; Wu, C. C.-C.; Meier, J. L.

10.1101/2024.07.25.605208 — developmental biology — Posted on 2024-07-26

870 Decoding RNA Metabolism by RNA-linked CRISPR Screening in Human Cells

Nugent, P. J.; Park, H.; Wladyka, C. L.; Chen, K. Y.; Bynum, C.; Quarterman, G.; Hsieh, A. C.; Subramaniam, A. R.

10.1101/2024.07.25.605204 — molecular biology — Posted on 2024-07-26

871 Adipogenin Dictates Adipose Tissue Expansion by Facilitating the Assembly of a Dodecameric Seipin Complex

Li, C.; Sun, X.-N.; Funcke, J.-B.; Vanharanta, L.; Joffin, N.; Li, Y.; Prasanna, X.; Paredes, M.; Joung, C.; Gordillo, R.; voros, C.; Kulig, W.; Straub, L.; Chen, S.; Velasco, J.; Cobb, A.; Padula, D.; Wang, M.-Y.; Onodera, T.; Varlamov, O.; Li, Y.; Liu, C.; Nawrocki, A.; Zhao, S.; Oh, D. Y.; Wang, Z.; Goodman, J.; Wynn, R. M.; Vattulainen, I.; Han, Y.; Ikonen, E.; Scherer, P. E.

10.1101/2024.07.25.605195 — cell biology — Posted on 2024-07-26

872 Interpretable representation learning for 3D multi-piece intracellular structures using point clouds

Vasan, R.; Ferrante, A.; Borensztejn, A.; Frick, C. L.; Gaudreault, N.; Mogre, S. S.; Morris, B.; Pires, G. G.; Rafelski, S. M.; Theriot, J. A.; Viana, M. P.

10.1101/2024.07.25.605164 — cell biology — Posted on 2024-07-26

873 CRISPR screens reveal ZBTB17/MIZ1 as a peroxisome regulator

Liu, H.; Chen, X.; Wang, H.; Zhuang, G.; Zhu, Z.-J.; Zhuang, M.

10.1101/2024.07.25.605214 — cell biology — Posted on 2024-07-26

874 Second generation of LNP based mRNA vaccine leads to a T-cell-inflamed tumor microenvironment favorable for improving PD-1/PD-L1 blocking therapy and long-term immunity in a cold tumor model

Fournier, C.; Mercey-Ressejac, M.; Derangere, V.; Al Kadi, A.; Rageot, D.; Charrat, C.; Leroy, A.; Escude, M.; Escaich, S.; Ghiringhelli, F.; Decaens, T.; Navarro, F. P.; Jouvin-Marche, E.; Marche, P. N.

10.1101/2024.07.24.604918 — immunology — Posted on 2024-07-26

875 WITHDRAWN: Extracting Auditory Emotion in Noise: A distributed auxiliary auditory network supporting affect processing of non-predictably obscured vocalisations

Swanborough, H.; Fruehholz, S.

10.1101/2024.06.18.599488 — neuroscience — Posted on 2024-07-26

876 Combined effects of pharmacological interventions and intermittent theta-burst stimulation on motor sequence learning

Kim, H.; Kornman, P. T.; Kweon, J.; Wassermann, E. M.; Wright, D. L.; Li, J.; Brown, J. C.

10.1101/2024.07.24.604878 — neuroscience — Posted on 2024-07-26

877 The Genetic Architecture of the Human Corpus Callosum and its Subregions

Bhatt, R.; Gadewar, S. P.; Shetty, A. K.; Ba Gari, I.; Haddad, E.; Javid, S.; Ramesh, A.; Nourollahimoghadam, E.; Zhu, A. H.; de Leeuw, C.; Thompson, P. M.; Medland, S. E.; Jahanshad, N.

10.1101/2024.07.22.603147 — neuroscience — Posted on 2024-07-26

878 Phonological representations of auditory and visual speech in the occipito-temporal cortex and beyond

Van Audenhaege, A.; Mattioni, S.; Cerpelloni, F.; Remi, G.; Arnaud, S.; Collignon, O.

10.1101/2024.07.25.605084 — neuroscience — Posted on 2024-07-26

879 "I'd like to think I'd be able to spot one if I saw one": How science journalists navigate predatory journals

Fleerackers, A.; Moorhead, L. L.; Alperin, J. P.

10.1101/2024.07.24.604934 — scientific communication and education — Posted on 2024-07-26

880 Re-analysis of mobile mRNA datasets highlights challenges in the detection of mobile transcripts from short-read RNA-Seq data

Paajanen, P.; Tomkins, M.; Hoerbst, F.; Veevers, R.; Heeney, M.; Thomas, H. R.; Apelt, F.; Saplaoura, E.; Gupta, S.; Frank, M.; Walther, D. J.; Faulkner, C.; Kehr, J.; Kragler, F.; Morris, R. J.

10.1101/2024.07.25.604588 — plant biology — Posted on 2024-07-26

881 The accomplices: Heparan sulfates and N-glycans foster SARS-CoV-2 spike:ACE2 receptor binding and virus priming

Paiardi, G.; Ferraz, M.; Rusnati, M.; Wade, R. C.

10.1101/2024.02.05.578888 — biophysics — Posted on 2024-07-26

882 Exploring the impacts of human breast milk functional lipidome on infant health and growth outcomes in early life using lipid bioinformatics

Ganeshalingam, M.; Cheema, S.; Wagner, C. L.; Pham, T. H.; Enstad, S.; Andrews, C.; Grapov, D.; Esposito, F.; Sen, S.; Thomas, R.

10.1101/2024.07.25.605136 — bioinformatics — Posted on 2024-07-26

883 WITHDRAWN: Antibiotic Bacteria Interaction: Dataset and Benchmarking.

Chatterjee, S.; Majumdar, A.; Chouzenoux, E.

10.1101/2024.02.22.581405 — bioengineering — Posted on 2024-07-26

884 Peer victimization in adolescence alters gene expression and cytokine profiles

Heumann, J.; Cole, S. W.; Eisner, M.; Ribeaud, D.; Gruenblatt, E.; Shanahan, M. J.

10.1101/2024.07.24.604965 — genomics — Posted on 2024-07-26

885 Genomic epidemiology and phenotypic characterisation of Salmonella entericaserovar Panama in Victoria, Australia

Thakur, S.; Baines, S. L.; Sia, C.; Valcanis, M.; Judd, L. M.; Howden, B. P.; Newton, H. J.; Ingle, D. J.

10.1101/2024.07.23.603842 — microbiology — Posted on 2024-07-26

886 WITHDRAWN: IL-17C plays a role in the pathophysiology of acute recurrent tonsillitis

Clapperton, M.; Kunanandam, T.; Florea, C. D.; Cunningham, M. R.; Douglas, C.; McConnell, G.

10.1101/2024.02.08.578879 — immunology — Posted on 2024-07-26

887 Reduced monitoring of task performance is an effective biomarker of autism

Zuk, N. J.; Weiss, Y.; Akrami, A.; Ahissar, M.

10.1101/2024.07.23.604831 — neuroscience — Posted on 2024-07-26

888 Factors behind poor cognitive outcome following a thalamic stroke

Vidal, J. P.; Danet, L.; Arribarat, G.; Pariente, J.; Peran, P.; Albucher, J.-F.; Barbeau, E. J.

10.1101/2024.07.24.604322 — neuroscience — Posted on 2024-07-26

889 Multivariate Neural Patterns of Reward and Anxiety in Adolescents with Anorexia Nervosa

Peel, H. J.; Reggente, N.; Strober, M.; Feusner, J.

10.1101/2024.07.23.604826 — neuroscience — Posted on 2024-07-26

890 WITHDRAWN: Geometrical determinant of nonlinear synaptic integration in human cortical pyramidal neurons

Yoon, J.

10.1101/2024.07.14.601255 — neuroscience — Posted on 2024-07-26

891 A review of co-occurrence and hybridization as neglected factors in studies of Syrianwoodpecker Dendrocopos syriacus and great spotted woodpecker Dendrocopos major

Bakai, A.; Gorman, G.; Kajtoch, L.

10.1101/2024.07.25.604904 — zoology — Posted on 2024-07-26

892 Biological Systematic of the genus Notodiaptomus Kiefer 1936 (Copepoda: Calanoida)

Geraldes Primeiro, L. J. O.; Cavalcanti, M. J.; Santos Silva, E. N.

10.1101/2024.07.23.604319 — zoology — Posted on 2024-07-26

893 ThunderBolt: An interactive data sharing and analysis platform for large-omics experiments

Geddes, T. A.; Chauduri, R.; Parker, B.; Yang, P.; Burchfield, J. G.

10.1101/2024.07.24.605014 — systems biology — Posted on 2024-07-26

894 A systematic review quantifying host feeding patterns of Culicoides species responsible for pathogen transmission

Fairbanks, E. L.; Tildesley, M. J.; Daly, J. M.

10.1101/2024.07.25.605155 — pathology — Posted on 2024-07-26

895 Testing the causal impact of amyloidosis on total Tau using a genetically informative sample of adult male twins.

Gillespie, N.; Neale, M. C.; Panizzon, M. S.; McKenzie, R. E.; Tu, X. M.; Reynolds, C. M.; Lyons, M. J.; Rissman, R. A.; Elman, J. A.; Franz, C. E.; Kremen, W. S.

10.1101/2024.07.23.602498 — pathology — Posted on 2024-07-26

896 NPMc+ and Flt3-ITD cooperation promotes a new oncogenic HSC state that supports transformation and leukemia stem cell maintenance

Colombo, E.

10.1101/2024.07.25.605115 — cancer biology — Posted on 2024-07-26

897 The minimal number of genes needed to identify a tumor

Gil, G.; Gonzalez, A.

10.1101/2024.07.25.604730 — cancer biology — Posted on 2024-07-26

898 Integrative analysis of single-cell gene expression: A comprehensive database approach

Nelson, T.; Thompson, G.

10.1101/2024.07.23.604709 — bioinformatics — Posted on 2024-07-26

899 Cross-view graph neural networks for spatial domain identification by integrating gene expression, spatial locations with histological images

Liu, S.; Guo, Y.; Zhang, Z.; Zhang, S.; Li, L.

10.1101/2024.07.25.605067 — bioinformatics — Posted on 2024-07-26

900 Genetic variation in the species Arabidopsis thaliana reveals the existence of natural heat resilience factors for meiosis

Zhao, J.; Fu, H.; Wang, Z.; Zhang, M.; Liang, Y.; Cui, X.; Pan, W.; Ren, Z.; Wu, Z.; Zhang, Y.; Gui, X.; Huo, L.; Lei, X.; Wang, C.; Schnittger, A.; Pawlowski, W. P.; Liu, B.

10.1101/2024.07.16.603532 — plant biology — Posted on 2024-07-26

901 Complete genome of the Medicago anthracnose fungus, Colletotrichum destructivum, reveals a mini-chromosome-like region within a core chromosome.

LAPALU, N.; SIMON, A.; Lu, A.; Plaumann, P.-L.; Amselem, J.; Pigne, S.; Auger, A.; Koch, C.; Dallery, J.-F.; O'Connell, R. J.

10.1101/2023.12.16.571984 — genomics — Posted on 2024-07-26

902 Is FAM19A5 an adipokine? Peripheral FAM19A5 in wild-type, FAM19A5 knock-out, and LacZ knock-in mice.

Kwak, H.; Cho, E.-H.; Cho, E. B.; Lee, Y.-N.; Shahapal, A.; Yong, H. J.; Reyes-Alcaraz, A.; Jeong, Y.; Lee, Y.; Lee, M.; Ha, N.; Oh, S.; Lee, J. K.; Lee, W. S.; Kim, W. K.; Hwang, J.-I.; Seong, J. Y.

10.1101/2020.02.19.955351 — genetics — Posted on 2024-07-26

903 Single nuclei transcriptomics reveal the differentiation trajectories of periosteal skeletal/stem progenitor cells in bone regeneration

Perrin, S.; Ethel, M.; Bretegnier, V.; Goachet, C.; Wotawa, C.-A.; Luka, M.; Coulpier, F.; Masson, C.; Menager, M.; Colnot, C.

10.1101/2023.06.23.546220 — cell biology — Posted on 2024-07-26

904 No evidence of musical training influencing the cortical contribution to the speech-FFR and its modulation through selective attention

Riegel, J.; Schueller, A.; Reichenbach, T.

10.1101/2024.07.25.605057 — neuroscience — Posted on 2024-07-26

905 Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

10.1101/2023.08.07.552264 — neuroscience — Posted on 2024-07-26

906 Combining systems and synthetic biology for in vivo enzymology

Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.

10.1101/2024.02.02.578620 — systems biology — Posted on 2024-07-26

907 TOR Inhibition Enhances Autophagic Flux and Immune Response in Tomato Plants Against PSTVd Infection

Silva-Valencia, S.; Prol, F. V.; Rodrigo, I.; Lison, P.; Belda-Palazon, B.

10.1101/2024.07.11.603042 — plant biology — Posted on 2024-07-26

908 Widely targeted metabolomics analysis reveals differences in volatile metabolites among four Angelica species

Ji, J. j.; Zang, L. l.; Lu, T. t.; Li, C.; Han, X. x.; Lee, S. R.; Wang, L.

10.1101/2022.12.01.518649 — plant biology — Posted on 2024-07-26

909 Effects of childhood hearing loss on the subcortical and cortical representation of speech

Calcus, A.; Rosen, S.

10.1101/2024.02.22.581639 — physiology — Posted on 2024-07-26

910 3D osteocyte lacunar morphometry of human bone biopsies with high resolution microCT: from monoclonal gammopathy to newly diagnosed multiple myeloma

Moreno-Jimenez, I.; Heinig, S.; Heras, U.; Maichl, D. S.; Strifler, S.; Leich, E.; Blouin, S.; Fratzl, P.; Fratzl-Zelman, N.; Jundt, F.; Cipitria, A.

10.1101/2023.07.12.548656 — bioengineering — Posted on 2024-07-26

911 OsHMA3 overexpression works more efficiently in generating low-Cd rice grain than OsNramp5 knockout mutation

Gui, Y.; Teo, J.; Tian, D.; Mohan, R.; Yin, Z.

10.1101/2024.07.11.603016 — bioengineering — Posted on 2024-07-26

912 Delving into human α1,4-galactosyltransferase acceptor specificity: the role of enzyme dimerization

Mikolajczyk, K.; Wroblewski, K.; Kmiecik, S.

10.1101/2024.03.21.586141 — biochemistry — Posted on 2024-07-26

913 ECM1 Attenuates Hepatic Fibrosis by Interfering with Mediators of Latent TGF-β1 Activation

Link, F.; Li, Y.; Zhao, J.; Munker, S.; Fan, W.; Nwosu, Z.; Yao, Y.; Wang, S.; Huang, C.; Hammad, S.; Liebe, R.; Liu, H.; Shao, C.; Gao, C.; Sun, B.; Torok, N. J.; Ding, H.; Ebert, M.; Weng, H.; Dijke, P. t.; Drasdo, D.; Dooley, S.; Wang, S.

10.1101/2023.12.12.571289 — cell biology — Posted on 2024-07-26

914 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts

Guo, Y.; Shu, S.; Zhou, Y.; Peng, W.; Jiang, Z.; Li, Y.; Li, T.; Du, F.; Wang, L.; Chen, X.; Dong, J.; Zhao, C.; Wang, M. H.; Sun, Y.; Sun, H.; Lu, L.; Digard, P.; Chang, K.-c.; Yen, H.-L.; Liu, J.; Pu, J.

10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-26

915 The forgotten wine: understanding the ecology and composition of palm wine fermentation

Sumerta, I. N.; Ruan, X.; Howell, K.

10.1101/2024.04.26.591403 — microbiology — Posted on 2024-07-26

916 Contributions of statistical learning to learning from reward feedback

Yazdanpanah, A.; Wang, C.; Trepka, E.; Benz, M.; Soltani, A.

10.1101/2024.04.27.591445 — neuroscience — Posted on 2024-07-26

917 Football as foraging? Movements by individual players and whole teams exhibit Levy walk dynamics

Shpurov, I.; Froese, T.; Ikegami, T. i.

10.1101/2024.06.11.598528 — systems biology — Posted on 2024-07-26

918 Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays

Shrestha, S.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lekkala, V. K. R.; Liu, J.; Yang, Y.; Joshi, P.; Lee, M.-Y.

10.1101/2024.03.25.586638 — bioengineering — Posted on 2024-07-26

919 PITPβ promotes COPI vesicle fission through lipid transfer and membrane contact formation

Park, K.; Ju, S.; Choi, H.; Gao, P.; Bang, G.; Choi, J. H.; Jang, J.; Morris, A.; Kang, B.-H.; Hsu, V. W.; Park, S.-Y.

10.1101/2024.05.27.596058 — cell biology — Posted on 2024-07-26

920 Direct RNA sequencing (RNA004) allows for improved transcriptome assessment and near real-time tracking of methylation for medical applications

Hewel, C.; Hofmann, F.; Dietrich, V.; Wierczeiko, A.; Friedrich, J.; Jenson, K.; Muendnich, S.; Diederich, S.; Sys, S.; Schartel, L.; Schweiger, S.; Helm, M.; Lemke, E. A.; Linke, M.; Gerber, S.

10.1101/2024.07.25.605188 — bioinformatics — Posted on 2024-07-25

921 The evolutionary fate of Neanderthal DNA in 30,780 admixed genomes with recent African-like ancestry

Pfennig, A.; Lachance, J.

10.1101/2024.07.25.605203 — evolutionary biology — Posted on 2024-07-25

922 Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviors in mice

Hu, B.; Geng, C.; Guo, F.; Liu, Y.; Wang, R.; Chen, Y.-T.; Hou, X.-Y.

10.1101/2024.07.25.604407 — neuroscience — Posted on 2024-07-25

923 Contrasting effects of competition on plant fitness and distributions along environmental gradients

Hayashi, K. T.; Kraft, N. J. B.

10.1101/2024.07.25.605199 — ecology — Posted on 2024-07-25

924 Exploring Mobile Genetic Elements in Vibrio cholerae

Drebes Dörr, N. C.; Lemopoulos, A.; Blokesch, M.

10.1101/2024.07.25.605194 — microbiology — Posted on 2024-07-25

925 The cold-inducible RNA-binding protein RBM3 stabilises viral mRNA at the cooler temperatures of the upper respiratory tract.

Coutts, H. L.; Turkington, H. L.; Bonazza, S.; Getty, E. M. P. E.; Sukumar, S.; Power, U. F.; Courtney, D. G.

10.1101/2024.07.25.605104 — microbiology — Posted on 2024-07-25

926 Age-related changes in 'cortical' 1/f dynamics are linked to cardiac activity

Schmidt, F.; Danboeck, S. K.; Trinka, E.; Klein, D. P.; Demarchi, G.; Weisz, N.

10.1101/2022.11.07.515423 — neuroscience — Posted on 2024-07-25

927 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.

10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-25

928 Iron-induced Transcriptional and Microbiome Changes in Host Roots Associated with Drought Tolerance in Sorghum

Kabir, A. H.; Brailey-Jones, P.; Abdelrahman, M.; Tran, L.-S. P.; Bennetzen, J. L.

10.1101/2024.07.19.604343 — plant biology — Posted on 2024-07-25

929 PGC-1a drives small cell neuroendocrine cancer progression towards an ASCL1-expressing subtype with increased mitochondrial capacity

Varuzhanyan, G.; Chen, C.-C.; Freeland, J.; He, T.; Tran, W.; Song, K.; Wang, L.; Cheng, D.; Xu, S.; Dibernardo, G. A.; Esedebe, F. N.; Bhatia, V.; Han, M.; Abt, E. R.; Park, J. W.; Memarzadeh, S.; Shackelford, D.; Lee, J. K.; Graeber, T.; Shirihai, O.; Witte, O. N.

10.1101/2024.04.09.588489 — cancer biology — Posted on 2024-07-25

930 Human P2X4 receptor gating is modulated by a stable cytoplasmic cap and a unique allosteric pocket

Shi, H.; Ditter, I. A.; Oken, A. C.; Mansoor, S. E.

10.1101/2024.07.25.605151 — biochemistry — Posted on 2024-07-25

931 Evolutionarily divergent Mycobacterium tuberculosis CTP synthase filaments are under selective pressure

Lynch, E. M.; Lu, Y.; Park, J. H.; Shao, L.; Kollman, J. M.; Rego, E. H.

10.1101/2024.07.25.605180 — biochemistry — Posted on 2024-07-25

932 Evolution of a central dopamine circuit underlies adaptation of light-evoked sensorimotor response in the blind cavefish, Astyanax mexicanus.

Kozol, R. A.; Canavan, A.; Tolentino, B.; Keene, A. C.; Kowalko, J. E.; Duboue, E. R.

10.1101/2024.07.25.605141 — evolutionary biology — Posted on 2024-07-25

933 The Impact of SARS-CoV-2 nsp14 Proofreading on Nucleoside Antiviral Activity: Insights from Genetic and Pharmacological Investigations

Peng, J.-Y.; Lahser, F.; Warren, C.; He, X.; Murray, E.; Wang, D.

10.1101/2024.07.24.604948 — molecular biology — Posted on 2024-07-25

934 Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

Chai, P.; Perr, J.; Kageler, L.; Lebedenko, C. G.; Dias, J. M. L.; Yankova, E.; Esko, J. D.; Tzelepis, K.; Flynn, R. A.

10.1101/2024.07.25.605163 — molecular biology — Posted on 2024-07-25

935 Spotted hyena gut cross-talks:Symbionts modulate mucosal immunity

Veloso Soares, S. P.; JarquinDiaz, V. H.; Veiga, M. M.; Karl, S.; Czirjak, G. A.; Weyrich, A.; Metzger, S.; East, M. L.; Hofer, H.; Heitlinger, E.; Benhaiem, S.; Martins Ferreira, S. C.

10.1101/2024.07.25.605121 — ecology — Posted on 2024-07-25

936 Prediction of protein subcellular localization in single cells

Zhang, X.; Tseo, Y.; Bai, Y.; Chen, F.; Uhler, C.

10.1101/2024.07.25.605178 — cell biology — Posted on 2024-07-25

937 Building Predictive Understanding of Microbial Ecology by Bridging Microbial Growth Kinetics and Microbial Population Dynamics

Cheng, Z.; Xia, W.; McKelvey, S.; He, Q.; Chen, Y.; Yuan, H.

10.1101/2024.07.25.605167 — microbiology — Posted on 2024-07-25

938 Climatic determinants of plant phenology in vernal pool habitats

Hendrickson, B.; Heckel, A.; Martin, R.; Sexton, J. P.

10.1101/2024.07.25.605166 — plant biology — Posted on 2024-07-25

939 Conformations of a Low-Complexity Protein in Homogeneous and Phase-Separated Frozen Solutions

Wilson, C. B.; Lee, M.; Yau, W.-M.; Tycko, R.

10.1101/2024.07.25.605144 — biophysics — Posted on 2024-07-25

940 Biom3d, a modular framework to host and develop 3D segmentation methods

Mougeot, G.; Safarbati, S.; Alegot, H.; Pouchin, P.; Field, N.; Almagro, S.; Pery, E.; Probst, A.; Tatout, C.; Evans, D. E.; Graumann, K.; Chausse, F.; Desset, S.

10.1101/2024.07.25.604800 — bioinformatics — Posted on 2024-07-25

941 Evaluation of AlphaFold3 for the fatty acids docking to human fatty acid-binding proteins

Nam, K. H.

10.1101/2024.07.25.605175 — bioinformatics — Posted on 2024-07-25

942 Bursts of rapid diversification, dispersals out of southern Africa, and two origins of dioecy punctuate the evolution of Asparagus

Bentz, P. C.; Burrows, J. E.; Burrows, S. M.; Mizrachi, E.; Liu, Z.; Yang, J.-B.; Mao, Z.; Popecki, M.; Seberg, O.; Petersen, G.; Leebens-Mack, J.

10.1101/2024.07.25.605174 — evolutionary biology — Posted on 2024-07-25

943 Scenarios for the emergence of new miRNA genes in the plant Arabidopsis halleri

Pavan, F.; Lacoste, E.; Castric, V.; Legrand, S.

10.1101/2024.07.25.605110 — evolutionary biology — Posted on 2024-07-25

944 Major change in swine influenza virus diversity in France owing to emergence and widespread dissemination of a newly introduced H1N2 1C genotype in 2020

Richard, G.; Herve, S.; Chastagner, A.; Queguiner, S.; Beven, V.; Hirchaud, E.; Barbier, N.; Gorin, S.; Blanchard, Y.; Simon, G.

10.1101/2024.07.25.605108 — evolutionary biology — Posted on 2024-07-25

945 Eco-evolutionary consequences of selective exploitation on metapopulations illustrated with Atlantic salmon

Lamarins, A.; Carlson, S. M.; Prevost, E.; Satterthwaite, W. H.; Buoro, M.

10.1101/2024.07.25.605173 — ecology — Posted on 2024-07-25

946 Substrate stiffness regulates neuronal maturation via Piezo1-mediated TTR activity

Kreysing, E.; Gautier, H.; Humphrey, R. J.; Mooslehner, K. A.; Muresan, L. A.; Haarhoff, D.; Mukherjee, S.; Zhao, X. X.; Winkel, A. K.; Dimitracopoulos, A.; Pillai, E. K.; Karadottir, R. T.; Franze, K.

10.1101/2024.07.25.605128 — developmental biology — Posted on 2024-07-25

947 The rich evolutionary history of the ROS metabolic arsenal shapes its mechanistic plasticity at the onset of metazoan regeneration

Vullien, A.; Amiel, A.; Baduel, L.; Diken, D.; Renaud, C.; Vervoort, M.; Rottinger, E.; Gazave, E.

10.1101/2024.07.25.605162 — developmental biology — Posted on 2024-07-25

948 Local DNA compaction creates TF-DNA clusters that enable transcription

Chabot, N. M.; Purkanti, R.; Del Panta, A.; Dalle Nogare, D.; Oda, H.; Kimura, H.; Jug, F.; Dal Co, A.; Vastenhouw, N. L.

10.1101/2024.07.25.605169 — cell biology — Posted on 2024-07-25

949 Mycobacterium avium subspecies paratuberculosis targets M cells in enteroid-derived monolayers through interactions with β1 integrins

Baruta, G.; Flannigan, K. L.; Alston, L.; Zhang, H.; De Buck, J.; Colarusso, P.; Hirota, S.

10.1101/2024.07.25.604189 — cell biology — Posted on 2024-07-25

950 Cell surface ribonucleoproteins cluster with heparan sulfate to regulate growth factor signaling

Flynn, R. A.; Chair, P.; Perr, J.; Kageler, L.; Lebedenko, C. G.; Dias, J. M. L.; Yankova, E.; Esko, J. D.; Tzelepis, K.

10.1101/2024.07.25.605163 — molecular biology — Posted on 2024-07-25

951 Coordinate control of the RNA polymerase II transcription cycle by CDK9-dependent, tripartite phosphorylation of SPT5

Sun, R.; Fisher, R. P.

10.1101/2024.07.25.605161 — molecular biology — Posted on 2024-07-25

952 Altering rRNA 2'O-methylation pattern during neuronal differentiation is regulated by FMRP

D'Souza, M. N.; Gowda, N. K. C.; Hariharan, N.; Qadri, S. W.; Palakodeti, D.; Muddashetty, R. S.

10.1101/2024.07.25.605157 — molecular biology — Posted on 2024-07-25

953 An optimised approach to evaluate variability in gut health markers in healthy adults.

Krüger, K.; Myeonghyun, Y.; van der Wielen, N.; Kok, D.; Hooiveld, G.; Keshtkar, S.; Diepenveen-de Bruin, M.; Balvers, M. G. J.; Grootte Bromhaar, M.; Mudde, K.; Ly, N. T. H. N.; Vermeiren, Y.; de Groot, L. C. P. G. M.; de Vos, R. C. H.; Gonzales, G. B.; Steegenga, W.; van Trijp, M.

10.1101/2024.07.25.604267 — microbiology — Posted on 2024-07-25

954 An orexin-sensitive subpopulation of layer 6 neurons regulates cortical excitability and anxiety behaviour.

Messore, F.; Therpurakal Narayanan, R.; Dufour, J. P.; Hoerder-suabedissen, A.; Guidi, L.; Korrell, K.; Mueller, M.; Lak, A.; Bannerman, D.; Mann, E. O.; Molnar, Z.

10.1101/2024.07.25.605138 — neuroscience — Posted on 2024-07-25

955 Endothelial TRPV4/Cx43 Signaling Complex Regulates Vasomotor Tone in Resistance Arteries

Burboa, P. C.; Gaete, P.; Shu, P.; Araujo, P. A.; Beuve, A.; Contreras, J. E.; Duran, W.; Lillo Gallardo, M. A.

10.1101/2024.07.25.604930 — physiology — Posted on 2024-07-25

956 SAVANA: reliable analysis of somatic structural variants and copy number aberrations in clinical samples using long-read sequencing

Elrick, H.; Sauer, C. M.; Espejo Valle-Inclan, J.; Trevers, K.; Tanguy, M.; Zumalave, S.; De Noon, S.; Muyas, F.; Cascao, R.; Afonso, A.; Amary, F.; Tirabosco, R.; Giess, A.; Freeman, T.; Sosinsky, A.; Piculell, K.; Miller, D. T.; Faria, C. C.; Elgar, G.; Flanagan, A. M.; Cortes-Ciriano, I.

10.1101/2024.07.25.604944 — cancer biology — Posted on 2024-07-25

957 Evaluation of Methodologies in Anti-nephrin Autoantibody Detection

Liu, P.; Liu, S.; Dalal, V.; Lane, J.; Gessaroli, E.; Forte, E.; Gallon, L.; Jin, J.

10.1101/2024.07.25.605154 — biochemistry — Posted on 2024-07-25

958 Distinct mechanisms of inhibition of Kv2 potassium channels by tetraethylammonium and RY785

Zhang, S.; Stix, R.; Orabi, E. A.; Bernhardt, N.; Faraldo-Gomez, J. D.

10.1101/2024.07.25.605170 — biochemistry — Posted on 2024-07-25

959 The metaplastic precursor state to oesophageal adenocarcinoma represents reversion to a transient epithelial cell state in the developing oesophagus

Baker, S.; Mullan, A.; Jennings, R.; Piper Hanley, K.; Ang, Y.; Palles, C.; Hanley, N.; Sharrocks, A.

10.1101/2024.07.25.605105 — developmental biology — Posted on 2024-07-25

960 The axillary lymphoid organ - an external, experimentally accessible immune organ in the zebrafish

Castranova, D.; Kenton, M. I.; Kraus, A.; Dell, C. W.; Park, J. S.; Venero Galanternik, M.; Park, G.; Lumbantobing, D. N.; Dye, L.; Marvel, M.; Iben, J.; Taimatsu, K.; Pham, V.; Willms, R. J.; Blevens, L.; Robertson, T. F.; Hou, Y.; Huttenlocher, A. F.; Foley, E.; Parenti, L. R.; Frazer, J. K.; Narayan, K.; Weinstein, B. M.

10.1101/2024.07.25.605139 — developmental biology — Posted on 2024-07-25

961 The role of dietary patterns in the polarization of angiogenic uterine Natural Killer cells during murine pregnancy

Lopes Salles, E.; Zavan, B.; Cabral Marcelino, R.; Shimaoka Chagas, P.; Mollica do Amarante-Paffaro, A.; Woodham, P.; Baban, B.; Paffaro Junior, V. A.

10.1101/2024.07.25.605132 — immunology — Posted on 2024-07-25

962 Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms

Bunbury, F.; Rivas, C.; Calatrava, V.; Malkovskiy, A.; Joubert, L.-M.; Parvate, A.; Evans, J. E.; Grossman, A. R.; Bhaya, D.

10.1101/2024.07.24.605005 — microbiology — Posted on 2024-07-25

963 Honoring the Afro-Colombian musical culture with the naming of Epipedobates sp. nov. (Anura: Dendrobatidae), a frog from the Pacific rainforests

Betancourth-Cundar, M.; Rios-Orjuela, J. C.; Crawford, A. J.; Cannatella, D. C.; Tarvin, R. D.

10.1101/2024.03.23.586415 — zoology — Posted on 2024-07-25

964 Phylogenomic Analysis of Target Enrichment and Transcriptome Data Uncovers Rapid Radiation and Extensive Hybridization in Slipper Orchid Genus Cypripedium L.

Lagou, L. J.; Kadereit, G.; Morales-Briones, D. F.

10.1101/2024.01.24.577114 — evolutionary biology — Posted on 2024-07-25

965 Refining the resolution of the yeast genotype-phenotype map using single-cell RNA-sequencing

N'Guessan, A.; Tong, W. Y.; Heydari, H.; Nguyen Ba, A. N.

10.1101/2023.10.18.562953 — evolutionary biology — Posted on 2024-07-25

966 The collective application of shorebird tracking data to conservation

Harrison, A.-L.; Stenzel, C.; Anderson, A.; Howell, J.; Lanctot, R. B.; Aikens, M.; Aldabe, J.; Berigan, L. A.; Bety, J.; Blomberg, E.; Bosi de Almeida, J.; Boyce, A. J.; Bradley, D. W.; Brown, S.; Carlisle, J.; Cheskey, E.; Christie, K.; Christin, S.; Clay, R.; Dayer, A.; Deppe, J. L.; English, W.; Flemming, S. A.; Gilg, O.; Gilroy, C.; Heath, S.; Hill, J. M.; Hipfner, J. M.; Johnson, J. A.; Johnson, L.; Kempenaers, B.; Knaga, P.; Kwon, E.; Lagasse, B. J.; Lamarre, J.-F.; Latty, C.; Leandri-Breton, D.-J.; Lecomte, N.; Loring, P.; McDuffie, L. A.; McGuire, R.; Moorhead, S.; Navedo, J. G.; News

10.1101/2024.01.30.576574 — ecology — Posted on 2024-07-25

967 RORγt-dependent antigen-presenting cells direct regulatory T cell-mediated tolerance to food antigen

Fu, L.; Upadhyay, R.; Pokrovskii, M.; Romero-Meza, G.; Griesemer, A.; Littman, D. R.

10.1101/2024.07.23.604803 — immunology — Posted on 2024-07-25

968 A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain

Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.

10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-07-25

969 Robust proteome profiling of cysteine-reactive fragments using label-free chemoproteomics

Biggs, G. S.; Cawood, E. E.; Vuorinen, A.; McCarthy, W. J.; Wilders, H.; Riziotis, I. G.; van der Zouwen, A. J.; Pettinger, J.; Nightingale, L.; Chen, P.; Powell, A. J.; House, D.; Boulton, S. J.; Skehel, J. M.; Rittinger, K.; Bush, J. T.

10.1101/2024.07.25.605137 — systems biology — Posted on 2024-07-25

970 Drug-loaded nanoparticles for cancer therapy: a high-throughput multicellular agent-based modeling study

Wang, Y.; Bucher, E.; Rocha, H.; Jadhao, V.; Metzcar, J.; Heiland, R.; Frieboes, H. B.; Macklin, P.

10.1101/2024.04.09.588498 — systems biology — Posted on 2024-07-25

971 Preventing evolutionary rescue in cancer

Patil, S.; Ahmed, A.; Viossat, Y.; Noble, R. J.

10.1101/2023.11.22.568336 — cancer biology — Posted on 2024-07-25

972 Single Turnover Transient State Kinetics Reveals Processive Protein Unfolding Catalyzed by Escherichia coli ClpB

Banwait, J. K.; Islam, L.; Lucius, A. L.

10.1101/2024.03.18.584833 — biophysics — Posted on 2024-07-25

973 Going around the bend to understand the role of leg coalescence in metachronal swimming

Tack, N. B.; Oliveira Santos, S.; Wilhelmus, M. M.

10.1101/2024.07.24.605009 — biophysics — Posted on 2024-07-25

974 Cryopreservation of neuroectoderm on a pillar plate and in situ differentiation into human brain organoids

Zolfaghar, M.; Acharya, P.; Joshi, P.; Choi, N. Y.; Shrestha, S.; Lekkala, V. K. R.; Kang, S.-Y.; Lee, M.; Lee, M.-Y.

10.1101/2024.07.25.605147 — bioengineering — Posted on 2024-07-25

975 Navigating the Night: Effects of Artificial Light on the Behaviour of Atlantic Puffin Fledglings

Brown, T. M.; Wilhelm, S. I.; Slepkov, A.; Baker, K.; Mastromonaco, G.; Burness, G.

10.1101/2024.04.24.590944 — animal behavior and cognition — Posted on 2024-07-25

976 Biomechanics of venom delivery in South America's first spitting scorpion

Laborieux, L.

10.1101/2024.07.25.605134 — evolutionary biology — Posted on 2024-07-25

977 Intracellular lipopolysaccharide regulates ER remodeling upon bacterial infection

Cheng, Y.-L.; Mello-Vieira, J.; Covarrubias-Pinto, A.; Gonzalez, A.; Kuncha, S. K.; Kew, C.; Zhang, K.; Afzal, M. A.; Diab, N.; Borchert, S.; Chen, W.; Huang, T. C.; Hornef, M.; Huebner, C. A.; Hensel, M.; Dikic, I.

10.1101/2024.07.25.605133 — cell biology — Posted on 2024-07-25

978 The plasmid-borne hipBA operon of Klebsiella michiganensis encodes a potent plasmid stabilization system

Shutt-McCabe, J.; Shaik, K. B.; Hoyles, L.; McVicker, G.

10.1101/2024.07.25.605072 — microbiology — Posted on 2024-07-25

979 Longitudinal genomic surveillance of a UK intensive care unit shows a lack of patient colonisation by multi-drug resistant Gram-negative pathogens

Snaith, A. E.; Moran, R. A.; Hall, R. J.; Casey, A.; Ratcliffe, L.; van Schaik, W.; Whitehouse, T.; McNally, A.

10.1101/2024.07.25.605077 — microbiology — Posted on 2024-07-25

980 Chemokines Kill Bacteria by Binding Anionic Phospholipids without Triggering Antimicrobial Resistance

Pontejo, S. M.; Martinez, S.; Zhao, A.; Barnes, K.; de Anda, J.; Alimohamadi, H.; Lee, E. Y.; Dishman, A. F.; Volkman, B. F.; Wong, G. C. L.; Garboczi, D. N.; Ballesteros, A.; Murphy, P. M.

10.1101/2024.07.25.604863 — microbiology — Posted on 2024-07-25

981 Systematic Analysis of the Glucose-PTS in Streptococcus sanguinis Highlighted its Importance in Central Metabolism and Bacterial Fitness

Taylor, Z. A.; Pham, D. N.; Zeng, L.

10.1101/2024.07.25.605150 — microbiology — Posted on 2024-07-25

982 Molecular dissection of the chromosome partitioning protein RocS and regulation by phosphorylation

Demuysere, M.; Ducret, A.; Grangeasse, C.

10.1101/2024.07.25.605149 — microbiology — Posted on 2024-07-25

983 Tripartite interaction of a patescibacterial epibiont, a methylotrophic gammaproteobacterial host and a jumbo phage

Buderka, F.; Lopez-Garcia, P.; Deschamps, P.; Krupovic, M.; Gutierrez-Preciado, A.; Ciobanu, M.; Bertolino, P.; David, G.; Moreira, D.; Jardillier, L.

10.1101/2024.03.08.584096 — microbiology — Posted on 2024-07-25

984 The deubiquitinating enzyme CYLD impairs NF-κB- and STAT1-dependent macrophage intrinsic immunity to Staphylococcus aureus

Schmidt, C.; Harit, K.; Traidl, S.; Werfel, T.; Roesner, L. M.; Nishanth, G. K.; Schlueter, D.

10.1101/2024.07.25.605106 — immunology — Posted on 2024-07-25

985 A Rose by any Other Name: Towards a quantitative theory of neuroimmune interactions

Fadai, N. T.; Turcanu, V.; Nicolau, D. V.

10.1101/2024.07.25.605114 — immunology — Posted on 2024-07-25

986 2'-O-Methyl-guanosine 3-base RNA fragments mediate essential natural TLR7/8 antagonism

Alharbi, A.; Sapkota, S.; Zhang, Z.; Jin, R.; Jayasekara, W. S.; Rupasinghe, E.; Speir, M.; Wilkinson-White, L.; Gamsjaeger, R.; Cubeddu, L.; Ellyard, J. I.; Wenholz, D.; McAllan, A.; Rezwan, R.; Ying, L.; Hosseini Far, H.; Bones, J.; He, S.; Yu, D.; Lennox, K.; Hertzog, P. J.; Vinuesa, C.; Behlke, M. A.; Ohto, U.; Laczka, O.; Corry, B.; Shimizu, T.; Gantier, M. P.

10.1101/2024.07.25.605091 — immunology — Posted on 2024-07-25

987 Investigating the antimicrobial and immunomodulatory effects of honeybee venom peptide apamin in the Drosophila genetic platform.

Wei, Y.; Jia, W.; Sun, Y.; Zhang, T.; Miao, H.; Wu, Z.; Dong, R.; Ning, F.; Kim, W. J.

10.1101/2024.07.25.605111 — immunology — Posted on 2024-07-25

988 Rescuing behavioral flexibility in a mouse model for OCD by enhancing reward-cue salience

van den Boom, B. J. G.; de Carlo, S.; van Klaveren, J.; Denys, D.; Willuhn, I.

10.1101/2024.07.25.604103 — neuroscience — Posted on 2024-07-25

989 No evidence of musical training influencing the cortical contribution to the speech-FFR and its modulation through selective attention

Riegel, J.; Schueller, A.; Reichenbach, T.

10.1101/2024.07.25.605057 — neuroscience — Posted on 2024-07-25

990 Control of tongue movements by the Purkinje cells of the cerebellum

Hage, P.; Fakharian, M. A.; Shoup, A. M.; Pi, J. S.; Sedaghat-Nejad, E.; Orozco, S. P.; Jang, I. K.; Looi, V.; Arginteanu, T.; Shadmehr, R.

10.1101/2024.07.25.604757 — neuroscience — Posted on 2024-07-25

991 Non-invasive Ultrasound Deep Neuromodulation of the Human Nucleus Accumbens Increases Win-Stay Behaviour

Yaakub, S. N.; Bault, N.; Lojkiewiez, M.; Bellec, E.; Roberts, J.; Philip, N.; Rushworth, M. F.; Fouragnan, E. F.

10.1101/2024.07.25.605068 — neuroscience — Posted on 2024-07-25

992 Modulation of Neuronal Excitability and Plasticity by BHLHE41 Conveys Lithium Non-Responsiveness

Rossner, M. J.; Stephan, M.; Papiol, S.; Zhang, M.; Song, J.; Frommeyer, S. M.; Haupt, H.; Jensen, N.; Kannaiyan, N.; Gupta, R.; Schuler, P.; Pickelmann, P.; McCarthy, M. J.; Schulte, E.; Lande, M.; Falkai, P.; Scheuss, V.; Schulze, T. G.; Zhang, W.

10.1101/2024.07.25.605130 — neuroscience — Posted on 2024-07-25

993 Plasticity in inhibitory networks improves pattern separation in early olfactory processing

Joshi, S.; Haney, S.; Wang, Z.; Locatelli, F.; Smith, B.; Cao, Y.; Bazhenov, M.

10.1101/2024.01.24.576675 — neuroscience — Posted on 2024-07-25

994 Precious3GPT: Multimodal Multi-Species Multi-Omics Multi-Tissue Transformer for Aging Research and Drug Discovery

Galkin, F.; Naumov, V.; Pushkov, S.; Sidorenko, D.; Urban, A.; Zagirova, D.; Alawi, K. M.; Aliper, A.; Gumerov, R.; Kalashnikov, A.; Mukba, S.; Pogorelskaya, A.; Ren, F.; Shneyderman, A.; Tang, Q.; Xiao, D.; Tyshkovskiy, A.; Ying, K.; Gladyshev, V. N.; Zhavoronkov, A.

10.1101/2024.07.25.605062 — bioinformatics — Posted on 2024-07-25

995 Robustness of time domain near infrared spectroscopy to variations in skin pigmentation

Lacerenza, M.; Amendola, C.; Bargigia, I.; Bossi, A.; Buttafava, M.; Calcaterra, V.; Contini, D.; Damagatla, V.; Negretti, F.; Rossi, V.; Spinelli, L.; Zanelli, S.; Zuccotti, G.; Torricelli, A.

10.1101/2024.07.25.605070 — bioengineering — Posted on 2024-07-25

996 Advancing Liver Gene Therapy: Enhanced Transduction with GalNAc-Bioconjugated rAAV Capsids

Lalys, P. A.; Bourdon, A.; Bouzelha, M.; Alvarez-Dorta, D.; Pavageau, K.; Girard, T.; Peumery, R.; Bouchouireb, Z.; Marchand, M.; Mellet, A.; Ledevin, M.; Depienne, S.; Guilbaud, M.; Croyal, M.; Gouin, S. G.; Roubinet, B.; Landemarre, L.; Adjali, O.; Ayuso, E.; Larcher, T.; Le Guiner, C.; MEVEL, M.; Deniaud, D.

10.1101/2024.07.25.605063 — bioengineering — Posted on 2024-07-25

997 TRAMP assembly alters the conformation and RNA binding of Mtr4 and Trf4-Air2

Denson, J.; Zhang, N.; Ball, D.; Thompson, K.; Johnson, S.; D'Arcy, S.

10.1101/2024.07.25.605035 — biochemistry — Posted on 2024-07-25

998 Shaping the Future: the importance of land use when projecting the future distribution of Endangered Amphibians and Reptiles.

Santostasi, N. L.; Serafini, C.; Maiorano, L.

10.1101/2024.07.25.605069 — ecology — Posted on 2024-07-25

999 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure

Legault, L.-M.; Dupas, T.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; McGraw, S.

10.1101/2023.09.30.560198 — developmental biology — Posted on 2024-07-25

1000 AP-1 Mediates Cellular Adaptation and Memory Formation During Therapy Resistance

Li, J.; Ravindran, P. T.; O'Farrell, A.; Busch, G. T.; Boe, R. H.; Niu, Z.; Woo, S.; Dunagin, M. C.; Jain, N.; Goyal, Y.; Sarma, K.; Herlyn, M.; Raj, A.

10.1101/2024.07.25.604999 — systems biology — Posted on 2024-07-25

1001 A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone

Gkioni, L.; Nespital, T.; Monzo, C.; Bali, J.; Nassr, T.; Cremer, A. L.; Beyer, A.; Backes, H.; Gronke, S.; Partridge, L.

10.1101/2024.07.25.605097 — physiology — Posted on 2024-07-25

1002 Single-molecule detection of transient dimerization of opioid receptors 2: Heterodimer blockage reduces morphine tolerance

Zhou, P.; Kasai, R. S.; Fujita, W.; Tsunoyama, T. A.; Ueda, H.; Pigolotti, S.; Fujiwara, T.; Kusumi, A.

10.1101/2024.07.25.605109 — biophysics — Posted on 2024-07-25

1003 Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers' effect on signaling and internalization

Zhou, P.; Tsunoyama, T. A.; Kasai, R. S.; Hirosawa, K. M.; Kalay, Z.; Aladag, A.; Fujiwara, T.; Pigolotti, S.; Kusumi, A.

10.1101/2024.07.25.605080 — biophysics — Posted on 2024-07-25

1004 Diet breadth in two polyphagous Spodoptera moths in a wide range of host and non-host plants and the potential for range expansion

Roy, A.; Waschke, N.; Chattington, S.; Modlinger, R.; Chakraborty, A.; Chirere, T. C.; Larsson, M. C.; Heckel, D. G.; Anderson, P.; Schlyter, F.

10.1101/2024.07.25.605058 — ecology — Posted on 2024-07-25

1005 V-ATPase Disassembly at the Yeast Lysosome-Like Vacuole Is aPhenotypic Driver of Lysosome Dysfunction in Replicative Aging

Hashmi, F.; Kane, P. M.

10.1101/2024.07.23.604825 — cell biology — Posted on 2024-07-25

1006 Co-recognition of histone acetylation and H3K4 trimethylation by GTE4-EML complex in Arabidopsis

Qian, F.; Zhao, Q.-Q.; Zhou, J.-X.; Yuan, D.-Y.; Su, Y.-N.; Li, L.; Chen, S.; He, X.-J.

10.1101/2024.07.25.605061 — molecular biology — Posted on 2024-07-25

1007 How to reward animals based on their subjective percepts: A Bayesian approach to online estimation of perceptual biases.

Dong, Y.; Lengyel, G.; Shivkumar, S.; Anzai, A.; DiRisio, G. F.; Haefner, R. M.; DeAngelis, G. C.

10.1101/2024.07.25.605047 — neuroscience — Posted on 2024-07-25

1008 Expectation modulates learning emotional words: Evidence from a hierarchical Bayesian model

Zhang, W.; Li, Y.; Zhou, C.; Li, B.; Liu, H.; Liu, M.

10.1101/2024.07.25.605051 — neuroscience — Posted on 2024-07-25

1009 Enhancing Statistical Power While Maintaining Small Sample Sizes in Behavioral Neuroscience Experiments Evaluating Success Rates

Theo, D.; Thevenet, M.; Garcia, S.; Lightning, A.; Didier, A.; Mandairon, N.; Kuczewski, N.

10.1101/2024.07.25.605060 — neuroscience — Posted on 2024-07-25

1010 Improved tests for the origin of allometric scaling across tree architectures

Chmurzynski, A.; Brummer, A. B.; Savage, V.; Shenkin, A.; Malhi, Y.; Martin-Ducup, O.; Zieminska, K.; Barbier, N.; Enquist, B. J.

10.1101/2024.07.25.605048 — plant biology — Posted on 2024-07-25

1011 Characterization of radiations-inducedgenomic structural variations in Arabidopsis thaliana

Sall, S. O.; Alioua, A.; Staerck, S.; Graindorge, S.; Pellicioli, M.; Schuler, J.; Raffy, Q.; Rousseau, M.; Molinier, J.

10.1101/2024.07.25.605065 — plant biology — Posted on 2024-07-25

1012 Non-destructive in situ monitoring of structural changes of 3D tumor spheroids during the formation, migration, and fusion process

Ning, K.; Xie, Y.; Sun, W.; Feng, L.; Fang, C.; Pan, R.; Li, Y.; Yu, L.

10.1101/2024.07.25.605064 — cancer biology — Posted on 2024-07-25

1013 Revealing a hidden conducting state by manipulating the intracellular domains in KV10.1 exposes the coupling between two gating mechanisms.

Abdelaziz, R.; Tomczak, A. P.; Neef, A.; Pardo, L. A.

10.1101/2023.07.24.549998 — biophysics — Posted on 2024-07-25

1014 Pre-trained Maldi Transformers improve MALDI-TOF MS-based prediction

De Waele, G.; Menschaert, G.; Vandamme, P.; Waegeman, W.

10.1101/2024.01.18.576189 — bioinformatics — Posted on 2024-07-25

1015 Spherical harmonics texture extraction for versatile analysis of biological objects

Gros, O.; Passmore, J. B.; Borst, N.; Kutra, D.; Nijenhuis, W.; Fuqua, T.; Kapitein, L. C.; Crocker, J. M.; Kreshuk, A.; Koehler, S.

10.1101/2024.07.25.605050 — bioinformatics — Posted on 2024-07-25

1016 Environmental "Wiggles" as Stabilizers of Species Range Limits Set by Interspecific Competition

Shirani, F.; Freeman, B. G.

10.1101/2024.07.24.605034 — ecology — Posted on 2024-07-25

1017 From egg to adult: a developmental table of the ant Monomorium pharaonis

Rajakumar, A.; Pontieri, L.; Li, R.; Larsen, R. S.; Vasquez-Correa, A.; Frandsen, J. K.; Rafiqi, A. M.; Zhang, G.; Abouheif, E.

10.1101/2020.12.22.423970 — developmental biology — Posted on 2024-07-25

1018 Extravascular spaces are the primary reservoir of antigenic diversity in Trypanosoma brucei infection

Beaver, A.; Keneskhanova, Z.; Cosentino, R. O.; Weiss, B. L.; Awuoche, E. O.; Smallenberger, G. M.; Buenconsejo, G. Y.; Crilly, N. P.; Smith, J. E.; Hakim, J. M.; Zhang, B.; Bobb, B.; Rijo-Ferreira, F.; Figueiredo, L. M.; Aksoy, S.; Siegel, T. N.; Mugnier, M. R.

10.1101/2022.06.27.497797 — microbiology — Posted on 2024-07-25

1019 Investigating the effects of age and hearing loss on speech intelligibility and amplitude modulation frequency selectivity

Regev, J.; Zaar, J.; Relano-Iborra, H.; Dau, T.

10.1101/2023.07.20.549841 — neuroscience — Posted on 2024-07-25

1020 Differential Reactivation of Task-Demand-Associated Firing Patterns in Subicular and CA1 Place Cells during a Hippocampal Memory Task

Seol, J.-M.; Lee, S.-M.; Lee, I.

10.1101/2024.07.24.605041 — neuroscience — Posted on 2024-07-25

1021 A neurofunctional signature of affective arousal generalizes across valence domains and distinguishes subjective experience from autonomic reactivity

Zhang, R.; Gan, X.; Xu, T.; Yu, F.; Wang, L.; Song, X.; Jiao, G.; Liu, X.; Zhou, F.; Becker, B.

10.1101/2024.07.17.604003 — neuroscience — Posted on 2024-07-25

1022 Assessing the Relative Contributions of Mosaic and Regulatory Developmental Modes from Single-Cell Trajectories

Song, S.; Villoutreix, P.

10.1101/2024.07.25.605053 — systems biology — Posted on 2024-07-25

1023 Neutraceuticals silybin B, resveratrol and epigallocatechin-3 gallate (EGCG) bind to troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro, in vivo, and in silico

Yang, Z.; Sheehan, A.; Messer, A.; Tsui, S.; Sparrow, A.; Redwood, C.; Kren, V.; Gould, I.; Marston, S.

10.1101/2024.05.09.593307 — biophysics — Posted on 2024-07-25

1024 Compound models and Pearson residuals for single-cell RNA-seq data without UMIs

Lause, J.; Ziegenhain, C.; Hartmanis, L.; Berens, P.; Kobak, D.

10.1101/2023.08.02.551637 — bioinformatics — Posted on 2024-07-25

1025 A novel method for integrating genomic and Tn-Seq data to identify common in vivo fitness mechanisms across multiple bacterial species

Fouts, D. E.; Clarke, T. H.; Brown, A. N.; Ottosen, E. N.; Holmes, C. L.; Moricz, B. S.; Mason, S.; Sinha, R.; Severin, G. B.; Anderson, M. T.; DiRita, V.; Bachman, M. A.; Mobley, H. L. T.

10.1101/2024.07.24.604993 — bioinformatics — Posted on 2024-07-25

1026 Computational stabilization of a non-heme iron enzyme enables efficient evolution of new function

King, B. R.; Sumida, K. H.; Caruso, J. L.; Baker, D.; Zalatan, J. G.

10.1101/2024.04.18.590141 — biochemistry — Posted on 2024-07-25

1027 The N-terminal Region of alpha-Synuclein Controls Amyloid Nucleation at the Condensate Interface

Thrush, R. J.; Vadukul, D. M.; Allerton, S. C.; Storch, M.; Aprile, F. A.

10.1101/2024.06.06.597302 — biochemistry — Posted on 2024-07-25

1028 High quality genome assembly and annotation (v1) of the eukaryotic terrestrial microalga Coccomyxa viridis SAG 216-4

Kraege, A.; Chavarro-Carrero, E.; Guiglielmoni, N.; Schnell, E.; Kirangwa, J.; Heilmann-Heimbach, S.; Becker, K.; Kohrer, K.; WGGC Team, ; DeRGA Community, ; Schiffer, P.; Thomma, B. P.; Rovenich, H.

10.1101/2023.07.11.548521 — genomics — Posted on 2024-07-25

1029 Genome-wide profiling of DNA repair proteins identifies higher-order coordination in single cells

de Luca, K. L.; Rullens, P. M.; Karpinska, M. A.; de Vries, S. S.; Gacek-Matthews, A.; Pongor, L. S.; Legube, G.; Jachowicz, J. W.; Oudelaar, A. M.; Kind, J.

10.1101/2023.05.10.540169 — genomics — Posted on 2024-07-25

1030 LCSKPOA: Enabling banded semi-global partial order alignments via efficient and accurate backbone generation through extended lcsk++

Weerakoon, M.; Saunders, C. T.; Heaton, H.

10.1101/2024.07.18.604181 — genomics — Posted on 2024-07-25

1031 Mitf over-expression leads to microphthalmia and coloboma in Mitf-cre mice

Longakit, A. N.; Bourget, H.; Van Raamsdonk, C. D.

10.1101/2024.07.24.605021 — genetics — Posted on 2024-07-25

1032 Experimental bleaching of photosymbiotic amoeba revealed strain-dependent differences in algal symbiosis ability.

Yamagishi, D.; Onuma, R.; Matsunaga, S.; Miyagishima, S.-y.; Maruyama, S.

10.1101/2024.07.24.604942 — evolutionary biology — Posted on 2024-07-25

1033 Sox10 is required for systemic initiation of bone mineralization

Gjorcheska, S.; Paudel, S.; McLeod, S.; Snape, L.; Camargo Sosa, K.; Duan, C.; Kelsh, R.; Barske, L.

10.1101/2024.07.24.604990 — developmental biology — Posted on 2024-07-25

1034 A Viral-Encoded Homologue of IPS-1 Modulates Innate Immune Signaling During KSHV Lytic Replication

Miranda, D.; He, B.; Sanchez, J. C.; Sennatti, A.; Bontemps, J.; Tran, J.; Tang, W. S.; Sanchez, D. J.

10.1101/2024.07.24.604690 — microbiology — Posted on 2024-07-25

1035 Polysaccharides induce deep-sea Lentisphaerae strains to release chronic bacteriophages

Wang, C.; Zheng, R.; Zhang, T.; Sun, C.

10.1101/2022.08.19.504481 — microbiology — Posted on 2024-07-25

1036 A metabolic atlas of the Klebsiella pneumoniae species complex reveals lineage-specific metabolism that supports persistent co-existence of diverse lineages

Vezina, B.; Cooper, H. B.; Rethoret-Pasty, M.; Brisse, S.; Monk, J. M.; Holt, K. E.; Wyres, K. L.

10.1101/2024.07.24.605038 — microbiology — Posted on 2024-07-25

1037 Leaky ribosomal scanning enables tunable translation of bicistronic ORFs in green algae.

Duenas, M. A.; Craig, R. J.; Gallaher, S. D.; Moseley, J. L.; Merchant, S. S.

10.1101/2024.07.24.605010 — plant biology — Posted on 2024-07-25

1038 Comparative Analysis of Glycoproteomic Software Using a Tailored Glycan Database

Hogan, R. A.; Pepi, L. E.; Riley, N. M.; Chalkley, R. J.

10.1101/2024.07.24.604997 — bioinformatics — Posted on 2024-07-25

1039 SimMS: A GPU-Accelerated Cosine Similarity implementation for Tandem Mass Spectrometry

Onoprishvili, T.; Yuan, J.-H.; Petrov, K.; Ingalalli, V.; Khederlarian, L.; Leuchtenmuller, N.; Chandra, S.; Duarte, A.; Bender, A.; Gloaguen, Y.

10.1101/2024.07.24.605006 — bioinformatics — Posted on 2024-07-25

1040 Unlocking data in Klebsiella lysogens to predict capsular type-specificity of phage depolymerases

Concha Eloko, R.; Sanjuan, R.; Beamud, B.; Domingo-Calap, P.

10.1101/2024.07.24.604748 — bioinformatics — Posted on 2024-07-25

1041 Identification of the trail-following pheromone receptor in termites

Diallo, S.; Kasparova, K.; Sulc, J.; Johny, J.; Krivanek, J.; Nebesarova, J.; Sillam-Dusses, D.; Kyjakova, P.; Vondrasek, J.; Machara, A.; Luksan, O.; Grosse-Wilde, E.; Hanus, R.

10.1101/2024.07.24.605012 — animal behavior and cognition — Posted on 2024-07-25

1042 Gaze audits food items for bite points during human withdraw-to-eat movements

Whishaw, I. Q.; Kuntz, J. R.; Ryait, H.; Phillip, J.; Kopples, J.; Dudley, J.; Karl, J. M.

10.1101/2024.07.24.604915 — animal behavior and cognition — Posted on 2024-07-25

1043 Long-Range Enhancer Networks Gradually Emerge as Key Regulators During Human Cortical Neurogenesis

Li, C.; Zhu, L.; Su, B.; Jia, L.; Hou, Y.; Cui, Z.; Luo, X.; Duan, J.; Guo, J.; Shi, M.; Chen, H.; Li, T.; Zhang, F.

10.1101/2024.07.24.605026 — genomics — Posted on 2024-07-25

1044 Scalable assessment of genome editing off-targets associated with genetic variants

Lin, J.; Nguyen, M. A.; Lin, L. Y.; Zeng, J.; Verma, A.; Neri, N. R.; da Silva, L. F.; Mucci, A.; Wolfe, S.; Shaw, K. L.; Clement, K.; Brendel, C.; Pinello, L.; Pellin, D.; Bauer, D. E.

10.1101/2024.07.24.605019 — genomics — Posted on 2024-07-25

1045 Tracking inflammation resolution signatures in lungs after SARS-CoV-2 omicron BA.1 infection of K18-hACE2 mice

Carolin, A.; Bishop, C. R.; Yan, K.; Nguyen, W.; Tang, B.; Rawle, D. J.; Suhrbier, A.

10.1101/2024.03.12.584739 — immunology — Posted on 2024-07-25

1046 Ultrastructural diversity of alpha-Synuclein pathology in the post-mortem brain of Parkinson patients: implications for Lewy Body formation

Lewis, A.; van den Heuvel, L.; Di Fabrizio, M.; Burger, D.; Huisman, E.; Bol, J. G.; van de Berg, W. D. J.; Stahlberg, H.

10.1101/2024.07.25.605088 — neuroscience — Posted on 2024-07-25

1047 Melanocortin system activates carotid body arterial chemoreceptors in hypertension

Pauza, A. G.; Thakkar, P.; Shen, X.; Felippe, I. S. A.; Rossmann, K.; Oya, M.; Nakamura, K.; Broichhagen, J.; Hodson, D. J.; Pauza, D. H.; Murphy, D.; Paton, J. F.

10.1101/2024.07.22.604704 — neuroscience — Posted on 2024-07-25

1048 PTF-Vac: Ab-initio discovery of plant transcription factors binding sites using explainable and generative deep co-learning encoders-decoders

Gupta, S.; Jyoti, ; Bhati, U.; Kesarwani, V.; Sharma, A.; Shankar, R.

10.1101/2024.01.28.577608 — bioinformatics — Posted on 2024-07-25

1049 Genomic prediction of metabolic content in rice grain in response to warmer night conditions

Bi, Y.; Walia, H.; Obata, T.; Morota, G.

10.1101/2024.07.23.604827 — genetics — Posted on 2024-07-25

1050 Ongoing local adaptation to climate change in yarrow (Achillea millefolium L.)

Losapio, G.; Doussot, B.; Araniti, F.; Bruno, L.; Guevara, R.; Dirzo, R.

10.1101/2024.07.22.604595 — evolutionary biology — Posted on 2024-07-25

1051 Successive pattern in winter wheat main stem structure modeling

Yin, J.; Zhu, C.; Li, Q.; Li, P.; Fan, C.; Gao, Y.

10.1101/2024.07.22.604639 — developmental biology — Posted on 2024-07-25

1052 Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway

Cantwell, H.; Nguyen, H.; Kettenbach, A.; Heald, R.

10.1101/2024.07.25.605073 — cell biology — Posted on 2024-07-25

1053 Endoglin regulates the integrity of the bone marrow vasculature

Rodriguez, D.; Jaykar, M.; Watts, D.; Sinha, A.; Gaete, D.; Krueger, A.; Mirtschink, P.; Rauner, M.; Chavakis, T.; Arthur, H. M.; Wielockx, B.

10.1101/2024.07.24.605039 — molecular biology — Posted on 2024-07-25

1054 Postnatal xanthine metabolism regulates cardiac regeneration in mammals

Saito, Y.; Sugiura, Y.; Sakaguchi, A.; Sada, T.; Nishiyama, C.; Maeda, R.; Kaneko, M.; Kiyonari, H.; Kimura, W.

10.1101/2024.07.24.605040 — developmental biology — Posted on 2024-07-25

1055 Dynamics in the intact fd bacteriophage revealed by pseudo 3D REDOR-based magic angle spinning NMR

Lusky, O. S.; Sherer, D.; Goldbourt, A.

10.1101/2024.06.17.598843 — biophysics — Posted on 2024-07-25

1056 Destabilisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation

Samuels, T. J.; Torley, E. J.; Naden, E. L.; Blair, P. E.; Hernandez Frometa, F. A.; Karam Teixeira, F.

10.1101/2024.07.24.604138 — developmental biology — Posted on 2024-07-25

1057 Structure, interaction, and nervous connectivity of beta cell primary cilia

Müller, A.; Klena, N.; Pang, S.; Garcia, L. E. G.; Topcheva, O.; Aurrecoechea Duran, S.; Sulaymankhil, D.; Seliskar, M.; Mziaut, H.; Schöniger, E.; Friedland, D.; Kipke, N.; Kretschmar, S.; Münster, C.; Weitz, J.; Distler, M.; Kurth, T.; Schmidt, D.; Hess, H. F.; Xu, C. S.; Pigino, G.; Solimena, M.

10.1101/2023.12.01.568979 — cell biology — Posted on 2024-07-25

1058 Effective lowering of α-synuclein expression by targeting G-quadruplex structures within the SNCA gene

Pirota, V.; Rey, F.; Esposito, L.; Fantini, V.; Pandini, C.; Maghraby, E.; Di Gerlando, R.; Doria, F.; Mella, M.; Pansarasa, O.; Gandellini, P.; Freccero, M.; Carelli, S.; Cereda, C.

10.1101/2024.02.09.579657 — molecular biology — Posted on 2024-07-25

1059 The human reward system encodes the subjective value of ideas during creative thinking

Moreno-Rodriguez, S.; Beranger, B.; Volle, E.; Lopez-Persem, A.

10.1101/2024.03.07.583926 — neuroscience — Posted on 2024-07-25

1060 Spatiotemporal dispersion of DENV1 genotype V in western Colombia

Rojas-Gallardo, D.; Ferrell, T.; Paula, E.; Lopez, D.; Giraldo, B.; Restrepo-Chica, J.; Jimenez-Posada, E.; Martinez-Gutierrez, M.; Ruiz-Saenz, J.; Key, A.; Shariatzadeh, N.; Khosravi, D.; Martinez, M. A.; Bombin, A.; Waggoner, J. J.; Osorio, J. E.; Neufeldt, C. J.; Collins, M. H.; Cardona-Ospina, J. A.; Piantadosi, A.

10.1101/2024.07.24.605015 — evolutionary biology — Posted on 2024-07-25

1061 Does early-life food shortage alter the effect of elevated temperature on female life history?

Chung, M.-H.; Zang, C.; Moura-Campos, D.; Jennions, M. D.; Head, M. L.

10.1101/2024.07.24.605022 — ecology — Posted on 2024-07-25

1062 Changes in maternal blood and placental lipidomic profile in obesity and gestational diabetes: Evidence for sexual dimorphism

Kadam, L.; Velickovic, M.; Straton, K.; Nicora, C. D.; Kyle, J.; Wang, E.; Monroe, M.; Bramer, L.; Myatt, L.; Burnum-Johnson, K.

10.1101/2024.07.24.605016 — molecular biology — Posted on 2024-07-25

1063 Illuminating microbial mat assembly: Cyanobacteria and Chloroflexota cooperate to structure light-responsive biofilms

Bunbury, F.; Rivas, C.; Calatrava, V.; Malkovskiy, A.; Joubert, L.-M.; Parvate, A.; Evans, J. E.; Grossman, A. R.; Bhaya, D.

10.1101/2024.07.24.605005 — microbiology — Posted on 2024-07-25

1064 Flooding patterns shape microbial community in mangrove sediments

Vazquez-Rosas-Landa, M.; Perez-Ceballos, R.; Zaldivar-Jimenez, A.; Herreira-Pacheco, S. E.; Perez-Gonzalez, L. D.; Prieto-Davo, A.; Celis-Hernandez, O.; Canales-Delgadillo, J. C.

10.1101/2024.07.24.604998 — microbiology — Posted on 2024-07-25

1065 Laboratory experiments suggests limited impact of increased nitrogen deposition on snow algae blooms

Almela, P.; Elser, J. J.; Giersch, J. J.; Hotaling, S.; Rebbeck, V.; Hamilton, T.

10.1101/2024.07.24.604882 — microbiology — Posted on 2024-07-25

1066 Cerebellar systems consolidation driven by the temporal dynamics of Purkinje cell excitability

Seo, J.; Kim, Y. G.; Lee, Y.-S.; Kim, S. J.

10.1101/2024.07.24.604888 — neuroscience — Posted on 2024-07-25

1067 Cortico-subcortical dynamics in primate working memory

von Nicolai, C.; Siegel, M.

10.1101/2024.07.24.605013 — neuroscience — Posted on 2024-07-25

1068 In vivo quantification of anterior and posterior chamber volumes in mice: implications for aqueous humor dynamics

Kim, D.; Fang, R.; Zhang, P.; Sun, C.; Li, G.; Montgomery, C.; John, S. W. M.; Stamer, W. D.; Zhang, H. F.; Ethier, C. R.

10.1101/2024.07.24.604989 — physiology — Posted on 2024-07-25

1069 Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric R25CPTH(1-34) in an Osteoporotic Beagle Model

Shin, J.-O.; Lee, J.-b.; Lee, S.; Kim, J.

10.1101/2024.02.10.579779 — pathology — Posted on 2024-07-25

1070 Mechanical forces and ligand-binding modulate Pseudomonas aeruginosa PilY1 mechanosensitive protein

Cao-Garcia, F. J.; Walker, J. E.; Board, S.; Alonso-Caballero, A.

10.1101/2023.08.03.551776 — biophysics — Posted on 2024-07-25

1071 Going around the bend to understand the role of leg coalescence in metachronal swimming

Tack, N. B.; Oliveira Santos, S.; Wilhelmus, M. M.

10.1101/2024.07.24.605009 — biophysics — Posted on 2024-07-25

1072 A Regularized Cox Hierarchical Model for Incorporating Annotation Information in Predictive Omic Studies

Shen, D.; Lewinger, J. P.

10.1101/2024.03.09.584239 — bioinformatics — Posted on 2024-07-25

1073 Differential responses in the core, active site and peripheral regions of cytochrome c peroxidase to extreme pressure and temperature

Zawistowski, R. K.; Crane, B. R.

10.1101/2024.07.24.604936 — biochemistry — Posted on 2024-07-25

1074 Evolution of novel mimicry polymorphisms through Haldanes sieve and rare recombination

Deshmukh, R.; Baral, S.; Kizhakke, A. G.; Kuwalekar, M.; Kunte, K.

10.1101/2024.07.24.605018 — evolutionary biology — Posted on 2024-07-25

1075 Self-Assembled Chambered Cardiac Organoids for Modeling Cardiac Chamber Formation and Cardiotoxicity Assessment

Zou, X.; Wang, F.; Zheng, H.; Kong, T.; Pei, D.

10.1101/2024.07.25.605044 — cell biology — Posted on 2024-07-25

1076 Structures of transcription-translation coupling complexes at each stage of the translation cycle

Zhang, J.; Lu, G.; Zhou, W.; Yang, M.; Li, L.; Shao, H.; Zhou, X.; Chen, C.; Gao, Y.; Ebright, R. H.; Lin, J.; Wang, C.

10.1101/2024.03.13.584796 — molecular biology — Posted on 2024-07-25

1077 Tumor microenvironments impair T cell receptor affinity and function

Yuan, Z.; O'Melia, M. J.; Li, K.; Lyu, J.; Rosado, A. M.; Watson, V. E.; Ashkezari, A. H. K.; Zhou, F.; Kansal, V.; Kinney, B.; Travaglino, S.; Doudy, L. O.; Noel, R. K.; Lucas, S. N.; Kong, S. L.; Jothikumar, P.; Rohner, N. A.; Manspeaker, M. P.; Francis, D. M.; Bai, K.; Ge, C.; Rushdi, M. N.; Chingozha, L.; Ruiperez-Campillo, S.; Jiang, N.; Lu, H.; Schmitt, N. C.; Thomas, S. N.; Zhu, C.

10.1101/2022.09.11.507496 — immunology — Posted on 2024-07-25

1078 Dynamics of striatal action selection and reinforcement learning

Lindsey, J.; Markowitz, J. E.; Gillis, W. F.; Datta, S. R.; Litwin-Kumar, A.

10.1101/2024.02.14.580408 — neuroscience — Posted on 2024-07-25

1079 Modeling Nitric Oxide Diffusion and Plasticity Modulation in Cerebellar Learning

Trapani, A. M.; Sartori, C. A.; Gambosi, B.; Pedrocchi, A.; Antonietti, A.

10.1101/2024.07.24.604957 — neuroscience — Posted on 2024-07-25

1080 A family of bacterial Josephin-like deubiquitinases with an unusual cleavage mode

Hermanns, T.; Kolek, S.; Uthoff, M.; de Heiden, R. A.; Mulder, M. P. C.; Baumann, U.; Hofmann, K.

10.1101/2024.07.24.604956 — biochemistry — Posted on 2024-07-24

1081 Complete mitochondrial genomes of Eastern Massasauga (Sistrurus catenatus) and North American Racer (Coluber constrictor)

Chen, Y.; Chabot, A. A.; Swanson, B. J.; Lougheed, S. C.

10.1101/2024.07.24.604992 — genomics — Posted on 2024-07-24

1082 Population genetics meets ecology: a guide to individual-based simulations in continuous landscapes

Chevy, E. T.; Min, J.; Caudill, V.; Champer, S. E.; Haller, B. C.; Rehmann, C. T.; Smith, C. C. R.; Tittes, S.; Messer, P. W.; Kern, A. D.; Ramachandran, S.; Ralph, P. L.

10.1101/2024.07.24.604988 — evolutionary biology — Posted on 2024-07-24

1083 Biomimetic model of corticostriatal micro-assemblies discovers new neural code

Pathak, A.; Brincat, S. L.; Organtzidis, H.; Strey, H. H.; Senneff, S.; Antzoulatos, E. G.; Mujica-Parodi, L. R.; Miller, E. K.; Granger, R.

10.1101/2023.11.06.565902 — neuroscience — Posted on 2024-07-24

1084 A Mathematical Sequence Representing Tonic Action Potential Spike Trains

Keum, D.; Kim, K.-W.; Medina, A. E.

10.1101/2024.07.23.604868 — neuroscience — Posted on 2024-07-24

1085 TIPE drives a cancer stem-like phenotype by promoting glycolysis via PKM2/HIF-1alpha axis in melanoma

Tian, M.; Yang, L.; Zhao, Z.; Li, J.; Wang, L.; Yin, Q.; Hu, W.; Lou, Y.; Du, J.; Zhao, P.

10.1101/2023.11.14.567124 — cancer biology — Posted on 2024-07-24

1086 Redox Conduction Through Cytochrome 'Nanowires' Can Sustain Cellular Respiration

Guberman-Pfeffer, M. J.

10.1101/2024.04.03.587941 — biophysics — Posted on 2024-07-24

1087 BayesianSSA: a Bayesian statistical model based on structural sensitivity analysis for predicting responses to enzyme perturbations in metabolic networks

Hosoda, S.; Iwata, H.; Miura, T.; Tanabe, M.; Okada, T.; Mochizuki, A.; Sato, M.

10.1101/2024.03.14.585120 — bioinformatics — Posted on 2024-07-24

1088 Statistical Survey of Chemical and Geometric Patterns on Protein Surfaces as a Blueprint for Protein-mimicking Nanoparticles

McBride, J. M.; Koshevarnikov, A.; Siek, M.; Grzybowski, B.; Tlusty, T.

10.1101/2024.07.18.604221 — biochemistry — Posted on 2024-07-24

1089 Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis Thaliana populations

Gibbs, P.; Paril, J.; Fournier-Level, A.

10.1101/2024.07.09.601435 — genetics — Posted on 2024-07-24

1090 Estimating dispersal rates and locating genetic ancestors with genome-wide genealogies

Osmond, M.; Coop, G.

10.1101/2021.07.13.452277 — evolutionary biology — Posted on 2024-07-24

1091 Population responses to environmental stochasticity are primarily driven by survival-reproduction trade-offs and mediated by aridity

Santos, G. S.; Yang, X.; Gascoigne, S.; Compagnoni, A.; Dias, A.; Tuljapurkar, S. D.; Kajin, M.; Salguero-Gomez, R.

10.1101/2024.07.24.604949 — ecology — Posted on 2024-07-24

1092 A rapid method to determine the genetic lineage of Escherichia coli using open reading frame composition in the shallow sequencing

Yagi, N.; Uechi, A.; Hirai, I.

10.1101/2024.07.11.601999 — microbiology — Posted on 2024-07-24

1093 DNA O-MAP uncovers the molecular neighborhoods associated with specific genomic loci

Liu, Y.; McGann, C. D.; Krebs, M.; Perkins, T. A.; Fields, R.; Camplisson, C. K.; Hsu, C.; Avanessian, S.; Tsue, A. F.; Kania, E. E.; Shechner, D. M.; Beliveau, B. J.; Schweppe, D. K.

10.1101/2024.07.24.604987 — systems biology — Posted on 2024-07-24

1094 A rewiring of the earliest immune events leading to T-cell mediated disease following intestinal infection in a PINK1 knock out mouse model of Parkinsons disease

Recinto, S.; Kazanova, A.; Afanasiev, E.; MacDonald, A.; Premachandran, S.; Allot, A.; Bessaiah, H.; Cordeiro, B.; Mukherjee, S.; Pei, J.; McBride, H. M.; Trudeau, L.-E.; Gruenheid, S.; Stratton, J. A.

10.1101/2024.06.18.598931 — immunology — Posted on 2024-07-24

1095 Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation

Chen, L.; Chehade, H. D.; Chu, H.-Y.

10.1101/2024.07.24.604995 — neuroscience — Posted on 2024-07-24

1096 Contributions of short and long-range white matter tracts in dynamic compensation with aging

Chakraborty, P.; Saha, S.; Deco, G.; Banerjee, A.; Roy, D.

10.1101/2024.02.12.580030 — neuroscience — Posted on 2024-07-24

1097 Cisplatin drives mitochondrial dysregulation in sensory hair cells

Lee, D. S.; Schrader, A.; Zou, J.; Ang, W. H.; Warchol, M. E.; Sheets, L.

10.1101/2024.01.29.577846 — neuroscience — Posted on 2024-07-24

1098 Structural diversity and distribution of NMCP-class nuclear lamina proteins in streptophytic algae

Kosztyo, B. S.; Richards, E. J.

10.1101/2024.07.24.604981 — plant biology — Posted on 2024-07-24

1099 MYC and p53 alterations cooperate through VEGF signaling to repress cytotoxic T cell and immunotherapy responses in prostate cancer

Murphy, K. C.; DeMarco, K. D.; Zhou, L.; Lopez-Diaz, Y.; Ho, Y.-j.; Li, J.; Bai, S.; Simin, K.; Zhu, L. J.; Mercurio, A. M.; Ruscetti, M.

10.1101/2024.07.24.604943 — cancer biology — Posted on 2024-07-24

1100 Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity

Fazzari, E.; Azizad, D. J.; Yu, K.; Ge, W.; Li, M. X.; Nano, P. R.; Kan, R. L.; Tum, H. A.; Tse, C.; Bayley, N. A.; Haka, V.; Cadet, D.; Perryman, T.; Soto, J. A.; Wick, B.; Raleigh, D. R.; Crouch, E. E.; Patel, K. S.; Liau, L. M.; Deneen, B.; Nathanson, D. A.; Bhaduri, A.

10.1101/2024.07.24.604840 — cancer biology — Posted on 2024-07-24

1101 VEHoP: A Versatile, Easy-to-use, and Homology-based Phylogenomic pipeline accommodating diverse sequences

Li, Y.; Liu, X.; Chen, C.; Qiu, J.-W.; Kocot, K.; Sun, J.

10.1101/2024.07.24.604968 — bioinformatics — Posted on 2024-07-24

1102 Thioether-functionalized cellulose for the fabrication of oxidation-responsive biomaterial coatings and films

DuBois, E. M.; Herrema, K. E.; Simkulet, M. G.; Hassan, L. F.; O'Connor, P. R.; Sen, R.; O'Shea, T. M.

10.1101/2024.07.24.604973 — bioengineering — Posted on 2024-07-24

1103 Stress relaxation rates of myocardium from failing and non-failing hearts

Gionet-Gonzales, M.; Gathman, G.; Rosas, J.; Kunisaki, K. Y.; Inocencio, D. G. P.; Hakami, N.; Milburn, G. N.; Pitenis, A. A.; Campbell, K. S.; Pruitt, B. L.; Stowers, R. S.

10.1101/2024.07.24.604845 — bioengineering — Posted on 2024-07-24

1104 Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain

Wu, W.; Kumar, P.; Brautigam, C. A.; Cho, S.-C.; Baniasadi, H. R.; Kober, D. L.; Gilles-Gonzales, M.-A.

10.1101/2024.07.24.604967 — biochemistry — Posted on 2024-07-24

1105 Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations

Duan, H.; Skreta, M.; Cotta, L.; Rajaonson, E. M.; Dhawan, N.; Aspuru-Guzik, A.; Maddison, C. J.

10.1101/2024.07.22.604688 — biochemistry — Posted on 2024-07-24

1106 Similar Won't Make It: Coexistence, Habitat Availability and Suboptimal Restoration

Maresca, F.; Borthagaray, A. I.; Cunillera-Montcusi, D.; Soutullo, A.; Arim, M.

10.1101/2024.07.24.604984 — ecology — Posted on 2024-07-24

1107 Multiscale mechanics drive functional maturation of the vertebrate heart

Andrews, T. G.; Cornwall Scoones, J.; Ramel, M.-C.; Gupta, K.; Briscoe, J.; Priya, R.

10.1101/2024.07.24.604962 — developmental biology — Posted on 2024-07-24

1108 Sox10 is required for systemic initiation of bone mineralization

Barske, L.; Gjorcheska, S.; Paudel, S.; McLeod, S.; Snape, L.; Camargo Sosa, K.; Duan, C.; Kelsh, R.

10.1101/2024.07.24.604990 — developmental biology — Posted on 2024-07-24

1109 ETV4 and ETV5 Orchestrate FGF-Mediated Lineage Specification and Epiblast Maturation during Early Mouse Development

Simon, C. S.; Garg, V.; Kuo, Y.-Y.; Niakan, K. K.; Hadjantonakis, A.-K.

10.1101/2024.07.24.604964 — developmental biology — Posted on 2024-07-24

1110 Satellite stem cell dysfunction in Duchenne muscular dystrophy

Granet, J. A.; Robertson, R.; Filippelli, R. L.; Cusmano, A.; Li, S.; Yaqubi, M.; Stratton, J. A.; Chang, N. C.

10.1101/2024.07.24.604963 — cell biology — Posted on 2024-07-24

1111 Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization.

Sheikh, A.; Ganguli, D.; Vickers, T. J.; Singer, B.; Foulke-Abel, J.; Akhtar, M.; Khatoon, N.; Setu, B.; Basu, S.; Maier, N.; Beatty, W.; Chakraborty, S.; Bhuiyan, T. R.; Qadri, F.; Donowitz, M.; Fleckenstein, J. M.

10.1101/2024.07.24.604983 — microbiology — Posted on 2024-07-24

1112 Multi-omics analysis of a traditional fermented food reveals a byproduct-associated subpopulation of Neurospora intermedia for waste-to-food upcycling

Maini Rekdal, V.; Villalobos-Escobedo, J. M.; Rodriguez-Valeron, N.; Olaizola Garcia, M.; Prado Vasquez, D.; Rosales, A.; Sorensen, P. M.; Baidoo, E. E. K.; Calheiros de Carvalho, A.; Riley, R.; Lipzen, A.; He, G.; Yan, M.; Haridas, S.; Daum, C.; Yoshinaga, Y.; Ng, V.; . Grigoriev, I. V.; Munk, R.; Wijaya, C. H. H.; Nuraida, L.; Damayanti, I.; Keasling, J. D.

10.1101/2024.07.24.604980 — microbiology — Posted on 2024-07-24

1113 Satellite glial contact enhances differentiation and maturation of human induced sensory neurons

LeBlang, C. J.; Pazyra-Murphy, M. F.; Silagi, E.; Dasgupta, S.; Tsolias, M.; Miller, T.; Petrova, V.; Zhen, S.; Gerrish, K.; Jovanovic, V.; Castellano, D.; Ormanoglu, P.; Tristan, C.; Woolf, C. J.; Tasdemir-Yilmaz, O.; Segal, R. A.

10.1101/2024.07.24.604966 — neuroscience — Posted on 2024-07-24

1114 A genus-specific nsp12 region impacts polymerase assembly in Alpha- and Gammacoronaviruses

Hoferle, P. J.; Anderson, T. K.; Kirchdoerfer, R. N.

10.1101/2024.07.23.604833 — biochemistry — Posted on 2024-07-24

1115 Patient-specific responses to SMN2 splice-modifying treatments in spinal muscular atrophy fibroblasts

Signoria, I.; Zwartkruis, M. M.; Geerlofs, L.; Perenthaler, E.; Faller, K. M.; James, R.; McHale-Owen, H.; Green, J. W.; Kortooms, J. V.; Snellen, S. H.; Asselman, F.-L.; Gillingwater, T. H.; Viero, G.; Wadman, R. I.; van der Pol, W. L.; Groen, E. J.

10.1101/2024.07.24.604892 — molecular biology — Posted on 2024-07-24

1116 Deep mutational scanning of SARS-CoV-2 Omicron BA.2.86 and epistatic emergence of the KP.3 variant

Taylor, A. L.; Starr, T. N.

10.1101/2024.07.23.604853 — microbiology — Posted on 2024-07-24

1117 The presenting HLA determines fidelity of SARS-CoV-2 spike protein epitope prediction

Schutt, C. R.; Birol, D.; Lu, X.; Yamasaki, S.

10.1101/2024.07.24.604889 — immunology — Posted on 2024-07-24

1118 All atom molecular dynamics simulations enable ensemble refinement of flexible and mismodelled cryo-EM derived RNA structures

Posani, E.; Janos, P.; Haack, D.; Toor, N.; Bonomi, M.; Magistrato, A.; Bussi, G.

10.1101/2024.07.24.604258 — molecular biology — Posted on 2024-07-24

1119 First-Year Dynamics of the Anaerobic Microbiome and Archaeome in Infants Oral and Gastrointestinal Systems

Neumann, C. J.; Mohammadzadeh, R.; Woh, P. Y.; Kobal, T.; Pausan, M.-R.; Shinde, T.; Haid, V.; Mertelj, P.; Mahnert, A.; Kumpitsch, C.; Jantscher-Krenn, E.; Moissl-Eichinger, C.

10.1101/2024.07.24.604926 — microbiology — Posted on 2024-07-24

1120 High fat low carbohydrate diet is linked to protection against CNS autoimmunity

Ni, D.; Tan, J.; Reyes, J.; Senior, A.; Andrews, C.; Taitz, J.; Potier, C.; Wishart, C.; Spiteri, A. G.; Piccio, L.; King, N. J. C.; Barres, R.; Raubenheimer, D.; Simpson, S.; Nanan, R.; Macia, L.

10.1101/2024.07.23.604865 — immunology — Posted on 2024-07-24

1121 Aberration correction in long GRIN lens-based microendoscopes for extended field-of-view two-photon imaging in deep brain regions

Sattin, A.; Nardin, C.; Daste, S.; Moroni, M.; Reddy, I.; Liberale, C.; Panzeri, S.; Fleischmann, A.; Fellin, T.

10.1101/2024.07.24.604890 — neuroscience — Posted on 2024-07-24

1122 Refinement of the Brassica napus NLRome using RenSeq

Wu, J.; Mukhopadhyay, S.; Perez-Lopez, E.

10.1101/2024.07.24.604657 — plant biology — Posted on 2024-07-24

1123 MultiOmicsAgent: Guided extreme gradient-boosted decision trees-based approaches for biomarker-candidate discovery in multi-omics data

Settelmeier, J.; Goetze, S.; Boshart, J.; Fu, J.; Steiner, S. N.; Gesell, M.; Schueffler, P. J.; Salimova, D.; Pedrioli, P. G. A.; Wollscheid, B.

10.1101/2024.07.24.604727 — bioinformatics — Posted on 2024-07-24

1124 RNA recognition by minimal ProQ from Neisseria meningitidis

Basczok, M. M.; Olejniczak, M.

10.1101/2024.07.24.604975 — biochemistry — Posted on 2024-07-24

1125 Optimal merging of kinematic and kinetic information to determine the position of the whole body Center of Mass

Le Mouel, C.

10.1101/2024.07.24.604923 — animal behavior and cognition — Posted on 2024-07-24

1126 Adaptation to water salinity changes: phenotypic plasticity meets and moulds carry-over effects in sea rock-pool mosquitoes

Cordeschi, G.; Bisconti, R.; Mastrantonio, V.; Canestrelli, D.; Porretta, D.

10.1101/2024.07.24.604954 — ecology — Posted on 2024-07-24

1127 Stable centromere association of the yeast histone variant Cse4 requires its essential N-terminal domain

Popchock, A. R.; Hedouin, S.; Mao, Y.; Asbury, C. L.; Stergachis, A. B.; Biggins, S.

10.1101/2024.07.24.604937 — cell biology — Posted on 2024-07-24

1128 CIB2 as a Ca2+ Sensor for Auditory Mechano-Electrical Transduction and Linked to Genetic-Heterogeneity of TMC1 in Hearing Loss

Wu, S.; Lin, L.; Hu, Q.; Yao, X.; Wang, H.; Liu, S.; Liu, Q.; Lu, L.; Xi, Y.; Lin, Y.; Gong, J.; Hu, R.; Zhan, W.; Luo, Y.; He, G.; Liu, Z.; Xiong, W.; Wang, Q.; Xu, Z.; Bai, F.; Lu, Q.

10.1101/2024.07.24.604958 — molecular biology — Posted on 2024-07-24

1129 Detection and decontamination of chronic wasting disease prions during venison processing

Milstein, M. S.; Gresch, S. C.; Schwabenlander, M.; Li, M.; Bartz, J.; Bryant, D.; Christenson, P.; Lindsey, L.; Lurndahl, N.; Oh, S.-H.; Rowden, G.; Shoemaker, R.; Wolf, T. M.; Larsen, P. A.; Lichtenberg, S. S.

10.1101/2024.07.23.604851 — microbiology — Posted on 2024-07-24

1130 HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

Killian, J. T.; King, R. G.; Lucander, A. C.; Kizziah, J. L.; Fucile, C. F.; Diaz-Avalos, R.; Qiu, S.; Silva-Sanchez, A.; Mousseau, B. J.; Macon, K. J.; Callahan, A. R.; Yang, G.; Hossain, M. E.; Akther, J.; Houp, J. A.; Rosenblum, F. D.; Porrett, P. M.; Ong, S. C.; Kumar, V.; Saphire, E. O.; Kearney, J. F.; Randall, T. D.; Rosenberg, A. F.; Green, T. J.; Lund, F. E.

10.1101/2023.03.31.534734 — immunology — Posted on 2024-07-24

1131 Somatic hypermutation-mediated paratope flexibility improves the cross-reactivity of human malaria antibodies

Murugan, R.; Hanke, A.; Oludada, O. E.; Costa, G.; Flores-Garcia, Y.; Mustafa, G.; Li, K.; Huntwork, R. H. C.; Horn, G.; Sekaran, M.; Tomaras, G.; Zavala, F.; Levashina, E. A.; Ketchem, R. R.; Wade, R. C.; Wardemann, H.

10.1101/2024.07.24.604858 — immunology — Posted on 2024-07-24

1132 Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington's Disease Pathogenesis

Ikefuama, E. C.; Slaviero, A. N.; Schalau, R. C.; Gott, M. L.; Tree, M. O.; Dunbar, G. L.; Rossignol, J.; Hochgeschwender, U.

10.1101/2024.07.24.604946 — neuroscience — Posted on 2024-07-24

1133 CD2AP is Co-Expressed with Tropomyosin-Related Kinase A and Ras-Related Protein Rab-5A in Cholinergic Neurons of the Murine Basal Forebrain

Fitzsimons, L. A.; Atif-Sheikh, M.; Lovely, J.; Mueth, M.; Rice, M.; Kotredes, K. P. A.; Howell, G.; Harrison, B. J.

10.1101/2024.07.24.604961 — neuroscience — Posted on 2024-07-24

1134 Overlapping Cortical Substrate of Biomechanical Control and Subjective Agency

Veillette, J. P.; Chao, A. F.; Nith, R.; Lopes, P.; Nusbaum, H. C.

10.1101/2024.07.24.604976 — neuroscience — Posted on 2024-07-24

1135 Epigenetic control of metabolic identity across cell types

Pacheco, M. P.; Gerard, D.; Mangan, R. J.; Chapman, A. R.; Hecker, D.; Kellis, M.; Schulz, M. H.; Sinkkonen, L.; Sauter, T.

10.1101/2024.07.24.604914 — systems biology — Posted on 2024-07-24

1136 Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age

Sarver, D. C.; Saqib, M.; Chen, F.; Wong, G. W.

10.1101/2024.03.26.586781 — systems biology — Posted on 2024-07-24

1137 Rice JASMONIC ACID OXIDASES (OsJAO) control resting jasmonate metabolism to promote development and repress basal immune responses

Ndecky, S. Y.; Malherbe, L.; Villette, C.; Chalvon, V.; Meusnier, I.; Beltran-Valencia, D.; Baumberger, N.; Riemann, M.; Kroj, T.; Champion, A.; Heitz, T.

10.1101/2024.07.24.604933 — plant biology — Posted on 2024-07-24

1138 Discovery and evaluation of novel biomarkers reveal dasatinib as a potential treatment for a specific subtype of Triple-Negative Breast Cancer

Ortega-Alvarez, D.; Tebar-Garcia, D.; Casado-Pelaez, M.; Castillo-Agea, E.; Balibrea-Rull, J.; Olivares-Osuna, D.; Perez-Parra, D.; Guardia, C.; Musulen, E.; Vinuesa-Pitarch, E.; Sanchez-Lopez, E.; Postigo-Corrales, F.; Ballana, E.; Martinez-Cardus, A.; Margeli, M.; Esteller, M.; Fernandez-Ruiz, P. L.; Luengo-Gil, G.; Mereu, E.; Galan-Moya, E. M.; Rodilla, V.

10.1101/2024.07.24.603752 — cancer biology — Posted on 2024-07-24

1139 Negatively Charged alpha-Synuclein Condensate Modulates Partitioning of Molecules

Yang, Q.; Chen, S.; Zhang, P.; Lu, Z.; Chang, S.; Wong, L. E.

10.1101/2024.07.24.604760 — biophysics — Posted on 2024-07-24

1140 Size control and oscillations of active droplets in synthetic cells

Sastre, J.; Thatte, A. A.; Bergmann, A. M.; Stasi, M.; Tena-Solsona, M.; Weber, C. A.; Boekhoven, J.

10.1101/2024.07.24.604607 — biophysics — Posted on 2024-07-24

1141 A comprehensive guide through the fold and stability of cytochrome c with implications for disease

Yousaf, M. A.; Savoia, A.; Pastore, A.

10.1101/2024.07.24.604913 — bioinformatics — Posted on 2024-07-24

1142 PairK: Pairwise k-mer alignment for quantifying protein motif conservation in disordered regions

Halpin, J. C.; Keating, A. E.

10.1101/2024.07.23.604860 — bioinformatics — Posted on 2024-07-24

1143 Prediction of Hemolytic Peptides and their Hemolytic Concentration (HC50)

Rathore, A. S.; Kumar, N.; Choudhury, S.; Mehta, N. K.; Raghava, G. P. S.

10.1101/2024.07.23.604887 — bioinformatics — Posted on 2024-07-24

1144 Enhancing the Reverse Transcriptase Function in Taq Polymerase via AI-driven Multiparametric Rational Design

10.1101/2024.07.24.604875 — bioengineering — Posted on 2024-07-24

1145 Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament

Sutherland, E.; Harding, C. J.; Monceau De Bergendal, T. M. Y. D.; Florence, G. J.; Ackermann, K.; Bode, B. E.; Synowksy, S.; Sundaramoorthy, R.; Czekster, C. M.

10.1101/2024.07.24.604905 — biochemistry — Posted on 2024-07-24

1146 Sex-specific perching: Monitoring of artificial plants reveals dynamic female-biased perching behavior in the black soldier fly, Hermetia illucens (Diptera: Stratiomyidae)

Lemke, N. B.; Rollinson, L. N.; Tomberlin, J. K.

10.1101/2024.07.23.604854 — animal behavior and cognition — Posted on 2024-07-24

1147 Drug-induced cis-regulatory elements in human hepatocytes affect molecular phenotypes associated with adverse reactions

Gotoh-Saito, S.; Wada, R.; Kawaji, H.

10.1101/2024.07.24.604883 — genomics — Posted on 2024-07-24

1148 Meta-analysis of spatial genetic patterns among European saproxylic beetles - the influence of history and contemporary forest quality

Krovi, R. S.; Amer, N.; Kajtoch, L.; Oczkowicz, M.

10.1101/2024.07.24.604895 — genetics — Posted on 2024-07-24

1149 Phylotranscriptomics reveals convergent behavioral evolution associated with shared and unique mechanisms in cavity-nesting songbirds

Lipshutz, S. E.; Hibbins, M. S.; Bentz, A. B.; Buechlin, A. M.; Empson, T. A.; George, E. M.; Hauber, M. E.; Rusch, D. B.; Schelsky, W. M.; Thomas, Q. K.; Torneo, S. J.; Turner, A. M.; Wolf, S. E.; Woodruff, M. J.; Hahn, M. W.; Rosvall, K. A.

10.1101/2024.02.13.580205 — evolutionary biology — Posted on 2024-07-24

1150 Desmodium Volatiles in "Push-Pull' Agriculture and Protection Against the Fall Armyworm, Spodoptera frugiperda

Odermatt, D. M.; Chidawanyika, F.; Mutyambai, D. M.; Schmid, B.; Domeignoz Horta, L. A.; Tamiru, A.; Schuman, M. C.

10.1101/2024.07.24.604900 — ecology — Posted on 2024-07-24

1151 Behavioural variation in background colour matching and the effect of social environment in rock-pool mosquitoes

Cordeschi, G.; Porretta, D.; Canestrelli, D.

10.1101/2024.07.24.604960 — ecology — Posted on 2024-07-24

1152 A whole-body atlas of non-graded BMP signaling activity in a sea anemone

Knabl, P.; Moersdorf, D.; Genikhovich, G.

10.1101/2024.07.24.604959 — developmental biology — Posted on 2024-07-24

1153 ER-mitochondria distance is a critical parameter for efficient mitochondrial Ca2+ uptake and oxidative metabolism.

Dematteis, G.; Tapella, L.; Casali, C.; Talmon, M.; Tonelli, E.; Reano, S.; Ariotti, A.; Pessolano, E.; Malecka, M.; Chrostek, G.; Kilkoviene, G.; Umbrasas, D.; Distasi, C.; Grilli, M.; Ladds, G.; Filigheddu, N.; Fresu, L. G.; Mikoshiba, K.; Matute, C.; Ramos-Gonzalez, P.; Jekabsone, A.; Cali, T.; Brini, M.; Biggiogera, M.; Cavaliere, F.; Miggiano, R.; Genazzani, A. A.; Lim, D.

10.1101/2024.07.24.604907 — cell biology — Posted on 2024-07-24

1154 Generation of High-fidelity Blastocyst-like Structures from Porcine Expanded Pluripotent stem cell via Chemically inducing cell plasticity

Wei, Y.; Liao, Z.; Qi, X.; Zhang, S.; Du, X.; Yuan, S.

10.1101/2024.07.24.604931 — cell biology — Posted on 2024-07-24

1155 TORC1-dependent control of fission yeast cohesin

Besson, D.; Vaur, S.; Vazquez, S.; TOURNIER, S.; Gachet, Y.; Birot, A.; Claverol, S.; Marston, A.; Damdimopoulos, A.; Ekwall, K.; Javerzat, J.-P.

10.1101/2024.07.24.603895 — molecular biology — Posted on 2024-07-24

1156 An ultraconserved snoRNA-like element in long noncoding RNA CRNDE promotes ribosome biogenesis and cell proliferation

Lee, J.-S.; Dan, T.; Zhang, H.; Cheng, Y.; Rehfeld, F.; Brugarolas, J.; Mendell, J. T.

10.1101/2024.07.23.604857 — molecular biology — Posted on 2024-07-24

1157 Microscale Spatial Dysbiosis in Oral biofilms Associated with Disease

Grodner, B.; Wu, D. T.; Hahm, S.; Takayasu, L.; Wen, N.; Kim, D. M.; Chen, C.-Y.; De Vlaminck, I.

10.1101/2024.07.24.604873 — microbiology — Posted on 2024-07-24

1158 FhlA is a Formate Binding Protein

Al Fardan, A. A.; Koestler, B. J.

10.1101/2024.07.24.604796 — microbiology — Posted on 2024-07-24

1159 Dual host-bacterial gene expression to study pathogenesis and the regulation of virulence factors in tissue during respiratory infections

Di Marco, F.; Nicola, F.; Giannese, F.; Saliu, F.; Tonon, G.; de Pretis, S.; Cirillo, D. M.; Lore, N. I.

10.1101/2024.07.24.604897 — microbiology — Posted on 2024-07-24

1160 Unraveling the Role of Ctla-4 in Intestinal Immune Homeostasis: Insights from a novel Zebrafish Model of Inflammatory Bowel Disease

Qin, L.; Hu, C.; Zhao, Q.; Wang, Y.; Fan, D.; Lin, A.; Xiang, L.-x.; Chen, Y.; Shao, J.-z.

10.1101/2024.07.24.604955 — immunology — Posted on 2024-07-24

1161 Nuclear FAK aggravates CD8+ T cell exhaustion via the SP1-IL-6 axis in colorectal cancer

Kong, H.; Wu, X.; Yang, Q.; Wu, C.; Yu, X.; Yang, J.; Xie, D.; Dai, Y.; Chen, L.; Ma, P.; Dai, S.; Huang, L.; Chen, C.; Mi, P.; Peng, Y.; Shi, H.; Zhang, D.; Ke, N.; Hu, B.; Zhou, Z.; Cao, D.; Wang, P.; Chen, L.; Liu, Y.-H.; Jiang, H.

10.1101/2024.07.24.604770 — immunology — Posted on 2024-07-24

1162 Supervised Automation of Cell Counting in Confocal Microscopic Cochlear Imaging Datasets Using Macro in Imaris

Rahman, M. T.; Khan, N. A.; Mokbul, M. I.; Razu, I.; Fatima, S. M.; Lira, S. S.; Garcia, C.; Eckard, P.; Hansen, M. R.

10.1101/2024.07.24.604970 — immunology — Posted on 2024-07-24

1163 Different Roles of D1/D2 Medium Spiny Neurons in the Nucleus Accumbens in Pair Bond Formation of Male Mandarin Voles

Zhang, L.; Qu, Y.; Young, L. J.; Hou, W.; Liu, L.; Liu, J.; Wang, Y.; Li, L.; Guo, X.; Li, Y.; Huang, C.; Lv, Z.; Li, Y.-T.; Jia, R.; Lian, T.; He, Z.; Tai, F.-D.

10.1101/2024.07.24.604911 — neuroscience — Posted on 2024-07-24

1164 Neural correlates of phonetic categorization under auditory (phoneme) and visual (grapheme) modalities

Bidelman, G. M.; York, A.; Pearson, C.

10.1101/2024.07.24.604940 — neuroscience — Posted on 2024-07-24

1165 Longevity or Well-being? A Dual-Dimension Structure of Neuroticism

He, Y.; Xiao, J.; Hu, K.; Gao, T.; Yan, Y.; Wang, L.; Li, K.; Lei, W.; Zhao, K.; Dong, C.; Tian, X.; Ding, C.; Peng, Y.; Xian, J.; Huang, S.; Liu, X.; Li, L.; Zhang, P.; Zhang, Z.; He, S.; Li, A.; Liu, B.

10.1101/2024.07.23.604876 — neuroscience — Posted on 2024-07-24

1166 A Mathematical Sequence Representing Tonic Action Potential Spike Trains

Keum, D.; Kim, K.-W.; Medina, A. E.

10.1101/2024.07.23.604868 — neuroscience — Posted on 2024-07-24

1167 Neuron-specific partial reprogramming in the dentate gyrus impacts mouse behavior and ameliorates age-related decline in memory and learning.

Vilchez-Acosta, A.; Maza, M. d. C.; Parras, A.; Planells, A.; Pico, S.; Desdin-Mico, G.; Mrabti, C.; Branchina, C.; Yacoub Maroun, C.; Deigin, Y.; Ocampo, A.

10.1101/2024.07.24.604939 — neuroscience — Posted on 2024-07-24

1168 Investigation of a Novel Mouse Model of Prader-Willi Syndrome with Invalidation of Necdin and Magel2

Barelle, P.-Y.; Sicardi, A.; Schaller, F.; Buron, J.; Becquet, D.; Omnes, F.; Watrin, F.; Santos, C.; Menuet, C.; Francois-Bellan, A.-M.; Caron, E.; Klucznik, J.; Prevot, V.; Bouret, S. G.; Muscatelli, F.

10.1101/2024.07.24.604909 — systems biology — Posted on 2024-07-24

1169 An Organism-Level Quantitative Flux Model of Energy Metabolism in Mice

Yuan, B.; Doxsey, W.; Tok, O.; Kwon, Y. Y.; Inouye, K. E.; Hotamisligil, G.; Hui, S.

10.1101/2024.02.11.579776 — systems biology — Posted on 2024-07-24

1170 Expression and characterization of the complete cyanophage genome PP in the heterologous host Synechococcus elongatus PCC 7942

Li, G.; Feng, J.; Zhu, X.; Chai, Y.; Sun, T.; Jiang, J.

10.1101/2024.07.23.604706 — synthetic biology — Posted on 2024-07-24

1171 The m6A Reader ECT1 Mediates Seed Germination via the DAG2-ECT1-PHYB Regulatory Cascade in Arabidopsis

Li, Z.; Ma, Y.; Sun, W.; Ding, P.; Bu, Y.; Qi, Y.; Jia, C.; Lei, B.; Ma, C.

10.1101/2024.07.24.604550 — plant biology — Posted on 2024-07-24

1172 Haptoglobin and glutamine synthetase may biomark cachexia induced by anti-acute myeloid leukemia chemotherapy

Campelj, D. G.; Timpani, C. A.; Spiesberger, G.; Formosa, L. E.; Steele, J.; Zhang, H.; Schittenhelm, R. B.; Leow, L.; Goodman, C.; Rybalka, E.

10.1101/2024.07.24.604689 — physiology — Posted on 2024-07-24

1173 Loss of H3K9 trimethylation leads to premature aging

Mrabti, C.; Yang, N.; Desdin-Mico, G.; Alonso-Calleja, A.; Vilchez-Acosta, A.; Pico, S.; Parras, A.; Piao, Y.; Schoenfeldt, L.; Luo, S.; Haghani, A.; Brooke, R.; Maza, M. d. C.; Branchina, C.; Yacoub Maroun, C.; von Meyenn, F.; Naveiras, O.; Horvath, S.; Sen, P.; Ocampo, A.

10.1101/2024.07.24.604929 — physiology — Posted on 2024-07-24

1174 Compromised chronic efficacy of a Glucokinase Activator AZD1656 in mouse models for common human GCKR variants

Ford, B. E.; Chachra, S. S.; Alshawi, A.; Oakley, F.; Fairclough, R. J.; Smith, D. M.; Tiniakos, D.; Agius, L.

10.1101/2024.07.24.604910 — pharmacology and toxicology — Posted on 2024-07-24

1175 CRISPR-inhibition screen for lncRNAs linked to melanoma growth and metastasis

Petroulia, S.; Hockemeyer, K.; Tiwari, S.; Berico, P.; Shamloo, S.; Banijamali, S. E.; Vega-Saenz de Miera, E.; Gong, Y.; Thandapani, P.; Wang, E.; Schulz, M.; Tsirigos, A.; Osman, I.; Aifantis, I.; Imig, J.

10.1101/2024.07.24.604899 — cancer biology — Posted on 2024-07-24

1176 Chiral mismatch in collagen-mimetic peptides modulates cell migration through integrin-mediated molecular recognition

Remson, A.; Dellemme, D.; luciano, M.; Surin, M.; Gabriele, S.

10.1101/2024.07.23.604866 — biophysics — Posted on 2024-07-24

1177 Probing the modulation of enzyme kinetics by multi-temperature, time-resolved serial crystallography

Schulz, E. C.; Prester, A.; von Stetten, D.; Gore, G.; Hatton, C. E.; Bartels, K.; Leimkohl, J.-P.; Schikora, H.; Ginn, H. M.; Tellkamp, F.; Mehrabi, P.

10.1101/2021.11.07.467596 — biophysics — Posted on 2024-07-24

1178 Energetic portrait of the amyloid beta nucleation transition state

Arutyunyan, A.; Seuma, M.; Faure, A. J.; Bolognesi, B.; Lehner, B.

10.1101/2024.07.24.604935 — biophysics — Posted on 2024-07-24

1179 Rapid and memory-efficient analysis and quality control of large spatial transcriptomics datasets

Kover, B.; Vigilante, A.

10.1101/2024.07.23.604776 — bioinformatics — Posted on 2024-07-24

1180 PredIDR: Accurate prediction of protein intrinsic disorder regions using deep convolutional neural network

Han, K.-S.; Yun, S.-J.; Kim, C.-S.; Ri, C.-P.; Del Conte, A.; Piovesan, D.

10.1101/2024.07.24.604908 — bioinformatics — Posted on 2024-07-24

1181 MiCK: a database of gut microbial genes linked with chemoresistance in cancer patients

Shahzaib, M.; Manzoor, H.; Zubair, H.; Jabeen, F.; Kayani, M. U. R.

10.1101/2024.07.24.604921 — bioinformatics — Posted on 2024-07-24

1182 PrePR-CT: Predicting Perturbation Responses in Unseen Cell Types Using Cell-Type-Specific Graphs

Alsulami, R.; Lehmann, R.; Khan, S.; Lagani, V.; Gomez-Cabrero, D.; Kiani, N.; Tegner, J.

10.1101/2024.07.24.604816 — bioinformatics — Posted on 2024-07-24

1183 Revealing the principles of inter- and intra-domain regulation in a signaling enzyme via scanning mutagenesis

Jiang, Z.; van Vlimmeren, A. E.; Karandur, D.; Semmelman, A.; Shah, N. H.

10.1101/2024.05.13.593907 — biochemistry — Posted on 2024-07-24

1184 Evolutionary Origins of Self-sustained Kai Protein Circadian Oscillators

Mukaiyama, A.; Furuike, Y.; Ito-Miwa, K.; Onoue, Y.; Horiuchi, K.; Yamashita, E.; Akiyama, S.

10.1101/2024.07.23.604570 — biochemistry — Posted on 2024-07-24

1185 Overcoming the challenges of cascade reactions and complex substrates in natural product biocatalysis: Immobilization of a cyclodipeptide synthase.

Alvarado-Ramirez, L.; Sutherland, E.; Melchor-Martinez, E. M.; Parra-Saldivar, R.; Bonaccorso, A. D.; Czekster, C. M.

10.1101/2024.07.24.604810 — biochemistry — Posted on 2024-07-24

1186 Different RNA recognition by ProQ and FinO depends on the sequence surrounding intrinsic terminator hairpins

Mamonska, M. D.; Basczok, M. M.; Stein, E. M.; Olejniczak, M.

10.1101/2024.07.24.604972 — biochemistry — Posted on 2024-07-24

1187 Reprograming of the ubiquitin ligase Ubr1 by intrinsically disordered Roq1 through cooperating multifunctional motifs

Peters, N.; Kanngiesser, S.; Pajonk, O.; Salazar Claros, R.; Mogk, A.; Schuck, S.

10.1101/2024.07.24.604893 — biochemistry — Posted on 2024-07-24

1188 Mapping the space of protein binding sites with sequence-based protein language models

Oruc, T.; Kadukova, M.; Davies, T. G.; Verdonk, M.; Poelking, C.

10.1101/2024.07.24.604735 — biochemistry — Posted on 2024-07-24

1189 The Biochemical Effects of Carotenoids in Orange Carrots on the Colonic Proteome in a Mouse Model of Diet-induced Obesity

Balbuena, E.; Milhem, F.; Kiremitci, Z.; Williams, T. I.; Collins, L.; Shu, Q.; Eroglu, A.

10.1101/2024.07.23.604335 — biochemistry — Posted on 2024-07-24

1190 Vocal recognition of partners by female prairie voles

Warren, M.; Young, L. J.; Liu, R. C.

10.1101/2024.07.24.604991 — animal behavior and cognition — Posted on 2024-07-24

1191 Unraveling the relationship between cancer and life history traits in vertebrates

Bulls, S.; Platner, L.; Ayub, W.; Moreno, N.; Arditi, J.-P.; Dreyer, S.; McCain, S.; Wagner, P.; Burgstaller, S.; Davis, L. R.; Bruins - van Sonsbeek, L. G. R.; Fischer, D.; Lynch, V. J.; Claude, J.; Glaberman, S.; Chiari, Y.

10.1101/2022.07.12.499088 — evolutionary biology — Posted on 2024-07-24

1192 Waning immunity drives respiratory virus evolution and reinfection

Bull, J. J.; Koelle, K.; Antia, R.

10.1101/2024.07.23.604867 — evolutionary biology — Posted on 2024-07-24

1193 Genetic Evidence for Geographic Structure within the Neanderthal Population

Rogers, A. R.

10.1101/2023.07.28.551046 — evolutionary biology — Posted on 2024-07-24

1194 High prevalence of multi-drug resistant bacteria in faecal samples from UK passerine birds

Dunn, J. C.; Clegg, S. R.

10.1101/2024.07.24.604896 — ecology — Posted on 2024-07-24

1195 Contrasting defense strategies of oligotrophs and copiotrophs revealed by single-cell-resolved virus-host pairing of freshwater bacteria

Okazaki, Y.; Nishikawa, Y.; Wagatsuma, R.; Takeyama, H.; Nakano, S.-i.

10.1101/2024.07.24.604879 — ecology — Posted on 2024-07-24

1196 Chemical Induction of Longevity-Promoting Colanic Acid in the Host's Microbiota

Hu, G.; Cooke, M. B.; Wen, A. X.; Yu, X.; Wang, J.; Herman, C.; Wang, M. C.

10.1101/2024.07.23.604802 — developmental biology — Posted on 2024-07-24

1197 Coxsackievirus B infection invokes unique cell-type specific responses in primary human pancreatic islets

Veronese-Paniagua, D. A.; Hernandez-Rincon, D. C.; Taylor, J. P.; Tse, H. M.; Millman, J. R.

10.1101/2024.07.23.604861 — cell biology — Posted on 2024-07-24

1198 Experimental verification on "Telomere DNA and ribosomal DNA co-regulation model for cell senescence"

Huang, B.; Wu, Z.

10.1101/2024.07.23.604700 — cell biology — Posted on 2024-07-24

1199 Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment

Knudsen-Clark, A. M.; Mwangi, D.; Cazarin, J.; Morris, K.; Baker, C.; Hablitz, L. M.; McCall, M. N.; Kim, M.; Altman, B. J.

10.1101/2024.02.14.580339 — immunology — Posted on 2024-07-24

1200 The subthalamic nucleus contributes causally to perceptual decision-making in monkeys

Rogers, K.; Gold, J. I.; Ding, L.

10.1101/2024.04.09.588715 — neuroscience — Posted on 2024-07-24

1201 3D-Imaging of synapses in neuronal tissues with synchrotron X-ray ptychography

Bosch, C.; Aidukas, T.; Holler, M.; Pacureanu, A.; Mueller, E.; Peddie, C. J.; Zhang, Y.; Cook, P.; Collinson, L.; Bunk, O.; Menzel, A.; Guizar-Sicairos, M.; Aeppli, G.; Diaz, A.; Wanner, A.; Schaefer, A.

10.1101/2023.11.16.567403 — neuroscience — Posted on 2024-07-24

1202 Poly ADP-Ribose Signaling is Dysregulated in Huntington Disease Patients

Maiuri, T.; Bazan, C. B.; Harding, R. J.; Begeja, N.; Kam, T.-I.; Byrne, L. M.; Rodrigues, F. B.; Warner, M. M.; Neuman, K.; Mansoor, M.; Badiee, M.; Dasovich, M.; Wang, K.; Thompson, L. M.; Leung, A. K.; Andres, S. N.; Wild, E. J.; Dawson, T. M.; Dawson, V. L.; Arrowsmith, C. H.; Truant, R.

10.1101/2022.11.23.517669 — neuroscience — Posted on 2024-07-24

1203 Effects of working memory training on cognitive flexibility, dendritic spine density and long-term potentiation in female mice

Stavroulaki, V.; Vagiaki, L.-E.; Zafiri, M.; Nikolidakis, O.; Sidiropoulou, K.; Plataki, M.

10.1101/2024.07.24.603721 — neuroscience — Posted on 2024-07-24

1204 Differentiation of Acute Disseminated Encephalomyelitis from Multiple Sclerosis Using a Novel Brain Lesion Segmentation and Classification Pipeline

Radi, O.; Huang, A.; Murakami, K.

10.1101/2024.07.23.604829 — neuroscience — Posted on 2024-07-24

1205 A comprehensive chemotyping and gonadal regulation of seven kisspeptinergic neuronal populations in the mouse brain

Hernandez, V. S.; Zetter, M. A.; Hernandez-Perez, O. R.; Hernandez-Gonzalez, R.; Camacho-Arroyo, I. S.; Millar, R. P.; Eiden, L. E.; Zhang, L.

10.1101/2024.07.23.604881 — neuroscience — Posted on 2024-07-24

1206 Omics driven onboarding of the carotenoid producing red yeast Xanthophyllomyces dendrorhous CBS 6938

Tobin, E. E.; Collins, J. H.; Marsan, C. B.; Nadeau, G. T.; Mori, K.; Lipzen, A.; Mondo, S.; Grigoriev, I. V.; Young, E. M.

10.1101/2023.07.31.551333 — synthetic biology — Posted on 2024-07-24

1207 Nationally endorsed learning objectives to improve course design in introductory biology

Hennessey, K. M.; Freeman, S.

10.1101/2023.10.25.563732 — scientific communication and education — Posted on 2024-07-24

1208 Resolving the three-dimensional interactome of Human Accelerated Regions during human and chimpanzee neurodevelopment

Pal, A.; Noble, M. A.; Morales, M.; Pal, R.; Baumgartner, M.; Yang, J. W.; Yim, K. M.; Uebbing, S.; Noonan, J. P.

10.1101/2024.06.25.600691 — genomics — Posted on 2024-07-24

1209 Host trees partially explain the complex bacterial communities of two threatened saproxylic beetles

Kolasa, ; Krovi, R. S.; Plewa, ; Jaworski, ; Kadej, ; Smolis, ; Gutowski, ; Sucko, ; Ruta, ; Olbrycht, ; Saluk, ; Oczkowicz, ; Kajtoch,

10.1101/2024.07.24.604729 — genetics — Posted on 2024-07-24

1210 Diet of Andean leaf-eared mice (Phyllotis) living at extreme elevations on Atacama volcanoes: insights from metagenomics, DNA metabarcoding, and stable isotopes

Quezada-Romegialli, C.; Quiroga-Carmona, M.; D'Elia, G. D. F.; Harrod, C.; Storz, J. F.

10.1101/2024.07.23.604871 — evolutionary biology — Posted on 2024-07-24

1211 Imperfect symmetry facilitated the evolution of specificity and high-order stoichiometry in vertebrate hemoglobin

Cortez-Romero, C. R.; Lyu, J.; Pillai, A.; Laganowsky, A.; Thornton, J. W.

10.1101/2024.07.24.604985 — evolutionary biology — Posted on 2024-07-24

1212 Defensive symbiont genotype distributions are linked to parasitoid attack networks

Wu, T.; Rodrigues, A. A.; Fayle, T.; Henry, L.

10.1101/2024.07.24.604610 — ecology — Posted on 2024-07-24

1213 Preclinical evaluation of tissue-selective gene therapies for congenital generalised lipodystrophy

Tiwari, M.; Roumane, A.; Sommer, N.; Han, W. D.; Delibegovic, M.; Rochford, J.; Mcilroy, G. D.

10.1101/2024.06.27.600757 — molecular biology — Posted on 2024-07-24

1214 Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organism

Pimmett, V. L.; Douaihy, M.; Maillard, L.; Trullo, A.; Dufourt, J.; Lenden-Hasse, H.; Radulescu, O.; Lagha, M.

10.1101/2024.02.05.577724 — molecular biology — Posted on 2024-07-24

1215 Mutational landscape and molecular bases of echinocandin resistance

Durand, R.; Torbey, A. G.; Giguere, M.; Pageau, A.; Dube, A. K.; Lagüe, P.; Landry, C. R.

10.1101/2024.07.21.604487 — molecular biology — Posted on 2024-07-24

1216 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.

Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; Gogan, K. M.; O Gallchobhair, O.; Murphy, D. M.; O'Rourke, S. A.; O'Connell, F.; Nadarajan, P.; Phelan, J. J.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.

10.1101/2024.03.20.585747 — immunology — Posted on 2024-07-24

1217 Concurrent assessment of neurometabolism and brain hemodynamics to comprehensively characterize the functional brain response to psychotropic drugs: an S-ketamine study

Boucherie, D. E.; Reneman, L.; Booij, J.; Immink, R. V.; Hollmann, M. W.; Schrantee, A.

10.1101/2024.07.23.604721 — neuroscience — Posted on 2024-07-24

1218 Benchmarking tRNA-Seq quantification approaches by realistic tRNA-Seq data simulation identifies two novel approaches with higher accuracy

Smith, T. S.; Monti, M.; Willis, A. E.; Kalmar, L.

10.1101/2023.12.13.571582 — bioinformatics — Posted on 2024-07-24

1219 Does Sex-Differential Gene Expression Drive Sex-Differential Selection in Humans?

Ming, M. J.; Cheng, C.; Kirkpatrick, M.; Harpak, A.

10.1101/2024.07.23.604672 — evolutionary biology — Posted on 2024-07-24

1220 Anthropogenic climate change will likely outpace coral range expansion

Vogt-Vincent, N. S.; Pringle, J. M.; Cornwall, C. E.; McManus, L. C.

10.1101/2024.07.23.604846 — ecology — Posted on 2024-07-24

1221 Cell-Surface RNA Associates with Heparan Sulfate and RNA-Binding Proteins to Modulate Receptor-Ligand Interactions

Li, Z.; Joshi, B. S.; Wijdeven, R. H.; Santos-Barriopedro, I.; Shademan, M.; Bos, E.; Tanenbaum, M.; Boons, G.-J.; Sharp, T.; Vermeulen, M.; Raz, V.; Joo, C.

10.1101/2024.07.23.604836 — molecular biology — Posted on 2024-07-24

1222 A nuclear RNA degradation code for eukaryotic transcriptome surveillance

Soles, L. V.; Liu, L.; Zou, X.; Yoon, Y.; Li, S.; Tian, L.; Valdez, M.; Yu, A.; Yin, H.; Li, W.; Ding, F.; Seelig, G.; Li, L.; Shi, Y.

10.1101/2024.07.23.604837 — molecular biology — Posted on 2024-07-24

1223 Activating FcγRs on monocytes are necessary for optimal Mayaro virus clearance

Dunagan, M. M.; Dabilla, N.; McNinch, C.; Brenchley, J. M.; Dolan, P. T.; Fox, J. M.

10.1101/2024.07.23.604823 — immunology — Posted on 2024-07-24

1224 Two new species of Mylochromis species (Cichlidae) from Lake Malawi, Africa

Turner, G. F.

10.1101/2024.07.23.604847 — zoology — Posted on 2024-07-24

1225 Solid state NMR spectral editing of histidine, arginine and lysine using Hadamard encoding

Gopinath, T.; Kraft, A.; Shin, K.; Wood, N. A.; Marassi, F. M.

10.1101/2024.07.23.604848 — biophysics — Posted on 2024-07-24

1226 Genetic Architecture and Analysis Practices of Circulating Metabolites in the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program

Wang, N.; Ockerman, F. P.; Zhou, L. Y.; Grove, M. L.; Alkis, T.; Barnard, J.; Bowler, R. P.; Clish, C. B.; Chung, S.; Drzymalla, E.; Evans, A. M.; Franceschini, N.; Gerszten, R. E.; Gillman, M. G.; Hutton, S. R.; Kelly, R. S.; Kooperberg, C.; Larson, M. G.; Lasky-Su, J. A.; Meyers, D. A.; Woodruff, P. G.; Reiner, A. P.; Rich, S. S.; Rotter, J.; Silverman, E. K.; Ramachandran, V. S.; Weiss, S. T.; Wong, K. E.; Wood, A. C.; Wu, L.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Yarden, R.; Blackwell, T.; Smith, A. V.; Chen, H.; Raffield, L. M.; Yu, B.

10.1101/2024.07.23.604849 — bioinformatics — Posted on 2024-07-24

1227 Designer DNA Strand Displacement Reaction toward Controlled Release of Cargos

Hu, C.-H.; Veneziano, R.

10.1101/2024.07.23.604118 — bioengineering — Posted on 2024-07-24

1228 Mechanism-guided engineering of a minimal biological particle for genome editing

Ngo, W.; Peukes, J. T.; Baldwin, A.; Xue, Z. W.; Hwang, S.; Stickels, R. R.; Lin, Z.; Satpathy, A.; Wells, J. A.; Schekman, R.; Nogales, E.; Doudna, J. A.

10.1101/2024.07.23.604809 — bioengineering — Posted on 2024-07-24

1229 Sequencing 1206 genomes reveals origin and movement of Aedes aegypti driving increased dengue risk

Crawford, J. E.; Balcazar, D.; Redmond, S.; Rose, N. H.; Youd, H. A.; Lucas, E. R.; Sudirman Made Ali, R.; Al-Nazawi, A. M.; Badolo, A.; CHEN, C.-H.; Cosme, L. V.; Henke, J. A.; Hung, K. Y.; Kluh, S.; Liu, W. -L.; Maringer, K.; Micieli, M. V.; Pless, E.; Sombie, A. R.; Surendran, S. N.; Wahid, I.; Armbruster, P. A.; Weetman, D.; McBride, C. S.; Gloria-Soria, A.; Powell, J. R.; White, B. J.

10.1101/2024.07.23.604830 — genomics — Posted on 2024-07-24

1230 Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

Tandukar, B.; Deivendran, D.; Chen, L.; Cruz-Pacheco, N.; Sharma, H.; Xu, A.; Bandari, A. K.; Chen, D.; George, C.; Marty, A.; Cho, R. J.; Cheng, J.; Saylor, D.; Gerami, P.; Arron, S. T.; Bastian, B. C.; Shain, A. H.

10.1101/2024.07.23.604673 — genomics — Posted on 2024-07-24

1231 Idiosyncrasies unveiled: examining the pace, patterns and predictors of biotic diversification in peninsular India

Roy, P.; Joshi, J.

10.1101/2023.11.15.567174 — evolutionary biology — Posted on 2024-07-24

1232 The spread of antibiotic resistance is driven by plasmids amongst the fastest evolving and of broadest host range

Coluzzi, C.; Rocha, E. P. C.

10.1101/2024.07.23.604842 — evolutionary biology — Posted on 2024-07-24

1233 The battle of the sexes in humans is highly polygenic

Cole, J. M.; Scott, C. B.; Johnson, M. M.; Golightly, P. R.; Carlson, J.; Ming, M. J.; Harpak, A.; Kirkpatrick, M.

10.1101/2024.07.23.604850 — evolutionary biology — Posted on 2024-07-24

1234 Eco-evolutionary dynamics of pathogen immune-escape: deriving a population-level phylodynamic curve

Nielsen, B. F.; Saad-Roy, C. M.; Metcalf, C. J. E.; Viboud, C.; Grenfell, B. T.

10.1101/2024.07.23.604819 — ecology — Posted on 2024-07-24

1235 Astrogliosis And Neuroinflammation Underlie Scoliosis Upon Cilia Dysfunction

Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.

10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-07-24

1236 Comparative analysis of 43 distinct RNA modifications by nanopore tRNA sequencing

White, L. K.; Dobson, K.; del Pozo, S.; Bilodeaux, J. M.; Andersen, S. E.; Baldwin, A.; Barrington, C.; Koertel, N.; Martinez-Seidel, F.; Strugar, S. M.; Watt, K. E. N.; Mukherjee, N.; Hesselberth, J. R.

10.1101/2024.07.23.604651 — molecular biology — Posted on 2024-07-24

1237 The Structural Logic of Dynamic Signaling in the Escherichia coli Serine Chemoreceptor

Reyes, G. I.; Flack, C. E.; Parkinson, J. S.

10.1101/2024.07.23.604838 — molecular biology — Posted on 2024-07-24

1238 A single-cell atlas of the Culex tarsalis midgut during West Nile virus infection

Fitzmeyer, E. A.; Dutt, T. S.; Pinaud, S.; Graham, B.; Gallichotte, E. N.; Hill, J. L.; Campbell, C.; Ogg, H.; Howick, V. M.; Lawniczak, M.; Osborne Nishimura, E.; Merkling, S. H.; Henao-Tamayo, M.; Ebel, G. D.

10.1101/2024.07.23.603613 — microbiology — Posted on 2024-07-24

1239 Mechanisms of Anammox Adaptation to High Temperatures: Increased Cyclization of Ladderane Lipids and Proteomic Insights

Karmann, C.; Navratilova, K.; Behner, A.; Noor, T.; Danner, S.; Santrucek, J.; Podzimek, T.; Lopez Marin, M. A.; Hajslova, J.; Bartacek, J.; Lipovova, P.; Kouba, V.

10.1101/2024.07.23.604647 — microbiology — Posted on 2024-07-24

1240 RORγt-dependent antigen-presenting cells direct regulatory T cell-mediated tolerance to food antigen

Fu, L.; Upadhyay, R.; Pokrovskii, M.; Romero-Meza, G.; Griesemer, A.; Littman, D. R.

10.1101/2024.07.23.604803 — immunology — Posted on 2024-07-24

1241 Th2 cell extracellular vesicles promote eosinophil survival through the cytokine cargo IL-3 and prolong airway eosinophilia.

Bunn, K. E.; Giese-Byrne, B. G.; Pua, H. H.

10.1101/2024.07.23.600647 — immunology — Posted on 2024-07-24

1242 Lack of Single Amino Acids Transcriptionally Remodels Sensory Systems to Enhance the Intake of Protein and Microbiota

Ezra, G.; Henriques, S. F.; Munch, D.; Francisco, A. P.; Baltazar, C.; Elias, A. P.; Deplancke, B.; Ribeiro, C.

10.1101/2024.07.23.604616 — neuroscience — Posted on 2024-07-24

1243 Distinct subcircuits within the mesolimbic dopamine system encode the salience and valence of social stimuli

Cross, E. A.; Borland, J. M.; Shaughnessy, E. K.; Lee, S. D.; Vu, V.; Sambor, E. A.; Huhman, K. L.; Albers, H. E.

10.1101/2024.07.23.604824 — neuroscience — Posted on 2024-07-24

1244 Proprioception Impacts Body Perception in Healthy Aging: Insights from a Psychophysical and Computational Approach

Risso, G.; Bieri, M.; Bertoni, T.; Mastria, G.; Allet, L.; Serino, A.; Bassolino, M.

10.1101/2024.07.23.604821 — neuroscience — Posted on 2024-07-24

1245 Impaired experience-dependent inter-areal network connectivity across the visual cortex in Fmr1 KO mice

Cheng, X.; Nareddula, S.; Gao, H.-C.; Chen, Y.; Xiao, T.; Nadew, Y. Y.; Xu, F.; Edens, P. A.; Quinn, C. J.; Huang, F.; Kimbrough, A.; Chubykin, A. A.

10.1101/2024.07.23.601989 — neuroscience — Posted on 2024-07-24

1246 Multi-omic ADNI CSF and plasma data integration identifies distinct metabolic transitions in disease progression in Alzheimer's Disease

Paterson, T.; Rohrs, J.; Hohman, T. J.; Mapstone, M.; Levey, A. I.; Hood, L.; Funk, C. C.

10.1101/2024.07.23.604835 — neuroscience — Posted on 2024-07-24

1247 Examining the Central Auditory Processing Using a Multi-Feature ERP Paradigm to Phonetic, Prosodic and Acoustic Features

Zavogianni, M. I.; Kelic, M.; Honbolygo, F.

10.1101/2024.07.23.604852 — neuroscience — Posted on 2024-07-24

1248 Entorhinal cortex represents task-relevant remote locations independent of CA1

Aery Jones, E. A.; Low, I. I. C.; Cho, F. S.; Giocomo, L. M.

10.1101/2024.07.23.604815 — neuroscience — Posted on 2024-07-24

1249 Characterization of three resistance-breaking isolates of sugarcane mosaic virus from Rwanda and implications for maize lethal necrosis

Wilson, J. R.; Willie, K. J.; Stewart, L. R.; Redinbaugh, M. G.; Ohlson, E. W.

10.1101/2024.07.23.604352 — plant biology — Posted on 2024-07-24

1250 Δ133p53 and Δ160p53 isoforms of the tumor suppressor protein p53 exert dominant-negative effect primarily by co-aggregation

Zhao, L.; Punga, T.; Sanyal, S.

10.1101/2024.07.23.604790 — cancer biology — Posted on 2024-07-24

1251 Beware of Data Leakage from Protein LLM Pretraining

Hermann, L.; Fiedler, T.; Nguyen, H. A.; Nowicka, M.; Bartoszewicz, J. M.

10.1101/2024.07.23.604678 — bioinformatics — Posted on 2024-07-24

1252 Forecasting dominance of SARS-CoV-2 lineages by anomaly detection using deep AutoEncoders

Rancati, S.; Nicora, G.; Prosperi, M.; Bellazzi, R.; Salemi, M.; Marini, S.

10.1101/2023.10.24.563721 — bioinformatics — Posted on 2024-07-24

1253 In vivo-Active Soluble Epoxide Hydrolase-targeting PROTACs with Improved Potency and Stability

Nakane, K.; Morisseau, C.; Dowker-Key, P. D.; Benitez, G.; Aguilan, J. T.; Nagai, E.; Sidoli, S.; Hammock, B. D.; Bettaieb, A.; Shinoda, K.; Kitamura, S.

10.1101/2024.07.23.604814 — biochemistry — Posted on 2024-07-24

1254 SLC45A4 encodes a mitochondrial putrescine transporter that promotes GABA de novo synthesis

Colson, C.; Wang, Y.; Atherton, J. W.; Su, X.

10.1101/2024.07.23.604788 — biochemistry — Posted on 2024-07-24

1255 Parental-effect gene-drive elements under partial selfing, or why do Caenorhabditis genomes have hyperdivergent regions?

Rockman, M. V.

10.1101/2024.07.23.604817 — evolutionary biology — Posted on 2024-07-24

1256 Site-specific metabolic labeling reveals proteome-wide phospho-dynamics

Alevra, M.; Correa Marrero, M.; Kluever, V.; Mandad, S.; Hemandhar-Kumar, N.; Pan, K.-T.; van Gerwen, J.; Glowacki, S. K.; Wildhagen, H.; Ischebeck, T.; Liu, Y.; RIzzoli, S. O.; Urlaub, H.; Beltrao, P.; Fornasiero, E. F.

10.1101/2024.07.23.604744 — molecular biology — Posted on 2024-07-24

1257 Use of optimized single-cell RNA flow cytometry protocol identifies monocytes as main producers of type I interferon in mouse syngeneic tumors

Lam, K. C.; Chen, Q.; Goldszmid, R. S.

10.1101/2024.07.23.604694 — immunology — Posted on 2024-07-24

1258 Effector-Specific Neural Representations of Perceptual Decisions Independent of Motor Actions and Sensory Modalities

Esmeyer, M. F.; Schmidt, T. T.; Blankenburg, F.

10.1101/2024.07.23.604761 — neuroscience — Posted on 2024-07-24

1259 Assessing the balance between excitation and inhibition in chronic pain through the aperiodic component of EEG

Gil Avila, C.; May, E. S.; Bott, F. S.; Tiemann, L.; Hohn, V.; Heitmann, H.; Zebhauser, P. T.; Gross, J.; Ploner, M.

10.1101/2024.07.23.604775 — neuroscience — Posted on 2024-07-24

1260 Methodological approaches to derive the heartbeat-evoked potential: pastpractices and future recommendations

Virjee, R.-I.; Kandasamy, R.; Garfinkel, S.; Carmichael, D.; Yogarajah, M.

10.1101/2024.07.23.604405 — neuroscience — Posted on 2024-07-24

1261 Resolving artefacts in voltage-clamp experiments with computational modelling: an application to fast sodium current recordings

Lei, C. L.; Clark, A. P.; Clerx, M.; Wei, S.; Bloothooft, M.; de Boer, T. P.; Christini, D. J.; Krogh-Madsen, T.; Mirams, G. R.

10.1101/2024.07.23.604780 — systems biology — Posted on 2024-07-24

1262 Integrative multi-omics data elucidating the biosynthesis and regulatory mechanisms of furanocoumarins in Angelica dahurica

ji, j.; han, x.; zang, l.; li, y.; Lin, L.; hu, d.; sun, s.; ren, y.; Maker, G.; lu, z.; Wang, L.

10.1101/2024.07.23.604792 — synthetic biology — Posted on 2024-07-24

1263 What scRNA sequencing taught us about MGMT expression in glioblastoma

Alnahhas, I.; Khan, M.; Shi, W.

10.1101/2024.07.23.604798 — cancer biology — Posted on 2024-07-24

1264 A common CTRB misfolding variant associated with pancreatic cancer risk causes ER stress and inflammation in mice

Bodas, C.; Felipe, I.; Chanez, B.; Lafarga, M.; Lopez-de-Maturana, E.; Martinez-de-Villarreal, J.; del Pozo, N.; Malumbres, M.; Vargiu, P.; Cayuela-Lopez, A.; Peset, I.; Connelly, K. E.; Hoskins, J.; Mendez, R.; Amundadottir, L. E.; Malats, N.; Ortega, S.; Real, F. X.

10.1101/2024.07.23.604778 — cancer biology — Posted on 2024-07-24

1265 The single-cell make-up of adult diffuse glioma based on the 2021 WHO classification

Alnahhas, I.; Kayne, A.; Khan, M.; Shi, W.

10.1101/2024.07.23.604812 — cancer biology — Posted on 2024-07-24

1266 Amortized template-matching of molecular conformations from cryo-electron microscopy images using simulation-based inference

Dingeldein, L.; Silva-Sanchez, D.; Evans, L.; D'Imprima, E.; Grigorieff, N.; Covino, R.; Cossio, P.

10.1101/2024.07.23.604154 — biophysics — Posted on 2024-07-24

1267 Linking metastatic potential and viscoelastic properties of breast cancer spheroids via dynamics compression and relaxation in microfluidics

Tavasso, M.; Bordoloi, A. D.; Tanre, E.; Dekker, S. A. H.; Garbin, V.; Boukany, P.

10.1101/2024.07.23.604808 — biophysics — Posted on 2024-07-24

1268 Chromosome Numbers and Reproductive Life Cycles in Green Plants: A Genomic Perspective

Dhakal, R.; Wolf, P.; Harkess, A.

10.1101/2024.07.23.604804 — bioinformatics — Posted on 2024-07-24

1269 Towards Wearable Electromyography for Personalized Musculoskeletal Trunk Models using an Inverse Synergy-based Approach

Rook, J. W. A.; Sartori, M.; Refai, M. I.

10.1101/2024.07.23.603973 — bioengineering — Posted on 2024-07-24

1270 Genome admixture among four hare species in Iberia: focus on the broom hare (Lepus castroviejoi)

Souto, J.; Marques, J. P.; Farelo, L.; Costa, J.; Queiros, J.; Pietri, C.; Ballesteros, F.; Alves, P. C.; Boursot, P.; Melo-Ferreira, J.

10.1101/2024.07.23.604737 — evolutionary biology — Posted on 2024-07-24

1271 Stock identification of Mediterranean horse mackerel (Trachurus mediterraneus) through the analysis of morphometric characters in the Adriatic Sea.

Vasapollo, C.

10.1101/2024.07.23.604807 — ecology — Posted on 2024-07-24

1272 Leaf spectroscopy reveals drought response variation in Fagus sylvatica saplings from across the species' range

Kurath, D.; van Moorsel, S. J.; Klaver, J.; Voortman, T.; Siegried, B.; Bruegger, Y.-A.; Moradi, A.; Czyz, E. A.; de La Harpe, M.; Wiesenberg, G. L. B.; Schaepman, M. E.; Schuman, M. C.

10.1101/2024.07.23.604726 — ecology — Posted on 2024-07-24

1273 DNA polymerase {lambda}-driven targeted mutagenesis fordirected evolution in human cells

Aiello, D.; Ciciani, M.; Marelli, F.; Stancampiano, M.; De Sanctis, V.; Bertorelli, R.; Kheir, E. G. A.; Maule, G.; Cereseto, A.; Arosio, D.

10.1101/2024.07.23.604813 — molecular biology — Posted on 2024-07-24

1274 FISH, a new tool for in situ preservation of RNA in tissues of deep-sea mobile fauna.

Cueff-Gauchard, V.; Aube, J.; Lagadec, J.-R.; Bignon, L.; Lafontaine, J.-P.; Hernandez-Avila, I.; Marsaud, N.; Shillito, B.; Amand, L.; Roussel, E. G.; Cambon, M.-A.

10.1101/2024.07.23.604794 — molecular biology — Posted on 2024-07-24

1275 Protein Kinases MpkA and SepH Transduce Crosstalk Between CWI and SIN Pathways to Activate Protective Hyphal Septation Under Echinocandin Cell Wall Stress

Doan, A. G.; Schafer, J. E.; Douglas, C. M.; Quintanilla, M. S.; Morse, M. E.; Edwards, H.; Huso, W.; Gray, K. J.; Lee, J.; Dayie, J. K.; Harris, S.; Marten, M. R.

10.1101/2024.07.23.604799 — microbiology — Posted on 2024-07-24

1276 Two-factor synaptic consolidation reconciles robust memory with pruning and homeostatic scaling

Iatropoulos, G.; Gerstner, W.; Brea, J.

10.1101/2024.07.23.604787 — neuroscience — Posted on 2024-07-24

1277 Flexible Control of Motor Units: Is the Multidimensionality of Motor Unit Manifolds a Sufficient Condition?

Dernoncourt, F.; Avrillon, S.; Logtens, T.; Cattagni, T.; Farina, D.; Hug, F.

10.1101/2024.07.23.604408 — neuroscience — Posted on 2024-07-24

1278 Preventing plasmid multimer formation in commonly used synthetic biology plasmids

Vaisbourd, E.; Bren, A.; Alon, U.; Glass, D. S.

10.1101/2024.07.23.604805 — synthetic biology — Posted on 2024-07-24

1279 Temperature-dependant benefits and costs of cytoplasmic male sterility in snail Physa acuta

Bererd, S.; David, P.; Teulier, L.; Plenet, S.; Luquet, E.

10.1101/2024.07.23.604755 — evolutionary biology — Posted on 2024-07-24

1280 Destablisation of bam transcripts terminates the mitotic phase of Drosophila female germline differentiation

Samuels, T. J.; Torley, E. J.; Naden, E. L.; Blair, P. E.; Hernandez Frometa, F. A.; Karam Teixeira, F.

10.1101/2024.07.24.604138 — developmental biology — Posted on 2024-07-24

1281 Flexible hippocampal representation of abstract boundaries supports memory-guided choice.

Esposito, M.; Abdul, L.; Ghouse, A.; Rodriguez Aramendia, M.; Kaplan, R.

10.1101/2024.07.23.604745 — neuroscience — Posted on 2024-07-24

1282 Contrasting topologies of synchronous and asynchronous functional brain networks

McIntyre, C. C.; Bahrami, M.; Shappell, H. M.; Lyday, R. G.; Fish, J.; Bollt, E. M.; Laurienti, P. J.

10.1101/2024.07.23.604765 — neuroscience — Posted on 2024-07-24

1283 Whole-Body Networks: A Holistic Approach for Studying Aging

Stylianou, O.

10.1101/2024.07.23.604767 — neuroscience — Posted on 2024-07-24

1284 Sleep Fragmentation Modulates the Neurophysiological Correlates of Cognitive Fatigue

Benkirane, O.; Simor, P.; Mairesse, O.; Peigneux, P.

10.1101/2024.07.23.604738 — neuroscience — Posted on 2024-07-24

1285 scRNA-seq identifies unique macrophage population in murine model of ozone induced asthma exacerbation

Ray, J. L.; Walum, J.; Jelic, D.; Barnes, R.; Bentley, I. D.; Britt, R. J.; Englert, J.; Ballinger, M. N.

10.1101/2024.07.23.604740 — pharmacology and toxicology — Posted on 2024-07-24

1286 The Plasmodiophora brassicae effector PbEGF1 manipulates plant immunity and regulate primary infection

yang, h.; Xu, Y. S.; Zhao, Y. S.; Shu, Y. P.; Sun, X.; Du, J. B.

10.1101/2024.07.23.604797 — pathology — Posted on 2024-07-24

1287 Molecular insights into the modulation of the 5HT2A receptor by serotonin, psilocin, and the G protein subunit Gqalpha

Viohl, N.; Zanjani, A. A. H.; Khandelia, H.

10.1101/2024.07.23.604750 — biophysics — Posted on 2024-07-24

1288 Contrastive Learning for Graph-Based Biological Interaction Discovery: Insights from Oncologic Pathways

Nguyen, P.-N.

10.1101/2024.07.23.604746 — bioinformatics — Posted on 2024-07-24

1289 Seumetry: a versatile and comprehensive R toolkit to accelerate high-dimensional flow and mass cytometry data analysis

Borggrewe, M.; Flosbach, M.; Hamburg Intestinal Tissue Study Group, ; Bonn, S.; Bunders, M. J.

10.1101/2024.07.23.604747 — bioinformatics — Posted on 2024-07-24

1290 Towards a new standard in genomic data privacy: a realization of owner-governance

Zhang, J.; Ren, Y.; Au, M. H.; Chow, K.-H.; Zhou, Y.; Chen, L.; Zhao, Y.; Su, J.; Luo, R.

10.1101/2024.07.23.604393 — bioinformatics — Posted on 2024-07-24

1291 Predicting real-world navigation performance from a virtual navigation task in older adults

Goodroe, S.; Fernandez Velasco, P.; Gahnstrom, C.; Wiener, J.; Coutrot, A.; Hornberger, M.; Spiers, H. J.

10.1101/2024.07.23.604766 — animal behavior and cognition — Posted on 2024-07-24

1292 Mapping fitness landscapes to interpret sex allocation in hermaphrodites

Chen, K.-H.; Pannell, J. R.

10.1101/2024.07.23.604733 — evolutionary biology — Posted on 2024-07-24

1293 TwinEco: A Unified Framework for Dynamic Data-Driven Digital Twins in Ecology

Khan, T.; de Koning, K.; Endresen, D.; Chala, D.; Kusch, E.

10.1101/2024.07.23.604592 — ecology — Posted on 2024-07-24

1294 A dynamical analysis of the alignment mechanism between two interacting cells

Leech, V.; Dalwadi, M. P.; Manhart, A.

10.1101/2024.07.23.604626 — biophysics — Posted on 2024-07-24

1295 Chimerism and altruism

Hitchcock, T. J.; Patten, M. M.

10.1101/2024.07.23.604446 — evolutionary biology — Posted on 2024-07-24

1296 Purging of highly deleterious alleles through an extreme bottleneck

Stuart, O. P.; Cleave, R.; Magrath, M. J.; Mikheyev, A. S.

10.1101/2024.07.23.602943 — evolutionary biology — Posted on 2024-07-24

1297 Molecular and Mechanical Signatures Contributing to Epidermal Differentiation and Barrier Formation

Prado-Mantilla, A.; Ning, W.; Lechler, T.

10.1101/2024.07.23.604736 — developmental biology — Posted on 2024-07-24

1298 Novel fluorescence-based methods to determine infarct and scar size in murine models of reperfused myocardial infarction

Duplessis, A.; Elster, C.; Becher, S.; Engel, C.; Lang, A.; Kaldirim, M.; Jung, C.; Grandoch, M.; Kelm, M.; Pfeiler, S.; Gerdes, N.

10.1101/2024.07.19.604384 — pathology — Posted on 2024-07-24

1299 DFAST_QC: Quality Assessment and Taxonomic Identification Tool for Prokaryotic Genomes

Elmanzalawi, M.; Fujisawa, T.; Mori, H.; Nakamura, Y.; Tanizawa, Y.

10.1101/2024.07.22.604526 — genomics — Posted on 2024-07-24

1300 Host selection in European ectomycorrhizal Basidiomycetes affects their estimated spore volumes

Izumi, H.

10.1101/2024.07.22.604628 — microbiology — Posted on 2024-07-24

1301 T6SS-mediated competition by Stenotrophomonas rhizophila shapes seed-borne bacterial communities and seed-to-seedling transmission dynamics

Garin, T.; Brault, A.; Marais, C.; Briand, M.; Preveaux, A.; Simonin, M.; Barret, M.; Sarniguet, A.

10.1101/2024.07.22.604635 — microbiology — Posted on 2024-07-24

1302 Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen

Solomon, A.; Bossel Ben-Moshe, N.; Hoffman, D.; Trzebanski, S.; Yehezkel, D.; Vainman, L.; Netea, M. G.; Avraham, R.

10.1101/2024.07.19.604264 — immunology — Posted on 2024-07-24

1303 Concurrent assessment of neurometabolism and brain hemodynamics to comprehensively characterize the functional brain response to psychotropic drugs: an S-ketamine study

Boucherie, D. E.; Reneman, L.; Booij, J.; Immink, R. V.; Hollmann, M. W.; Schrantee, A. E.

10.1101/2024.07.23.604721 — neuroscience — Posted on 2024-07-24

1304 Therapeutic DBS for OCD Suppresses the Default Mode Network

Slepneva, N.; Basich-Pease, G.; Reid, L.; Frank, A. C.; Norbu, T.; Krystal, A. D.; Sugrue, L. P.; Motzkin, J. C.; Larson, P. S.; Starr, P. A.; Morrison, M. A.; Lee, A. M.

10.1101/2024.07.21.601827 — neuroscience — Posted on 2024-07-24

1305 Pulsed inhibition of corticospinal excitability by the thalamocortical sleep spindle

Hassan, U.; Okyere, P.; Masouleh, M. A.; Zrenner, C.; Ziemann, U.; Bergmann, T. O.

10.1101/2024.07.22.604668 — neuroscience — Posted on 2024-07-24

1306 Gene expression changes in long-term memory unlikely to replicate in the long term

Mukamel, E. A.; Yu, Z.

10.1101/2024.07.22.604349 — neuroscience — Posted on 2024-07-24

1307 Inflammatory Neuropathy in Mouse and Primate Models of Colorectal Cancer

Gaffney, C. M.; Casaril, A. M.; Mahmud, I.; Wei, B.; Valadez, K. M.; Kolb, E. A.; Cherry, F. R.; Guise, T. A.; Lorenzi, P. L.; Shi, L.; Hodo, C. L.; Shepherd, A. J.

10.1101/2024.07.19.604274 — neuroscience — Posted on 2024-07-24

1308 The dynamic crosstalk between cytoskeletal filaments regulates the cytoplasmic mechanics across the apicobasal axis

Ray, D.; Sinha, D.

10.1101/2024.07.23.604784 — cell biology — Posted on 2024-07-24

1309 Novel Approach for Refractive Index Matching in Calcified Tissues

Laudier, D.; Mora-Antionette, M.; Lewis, K. J.

10.1101/2024.07.23.604611 — cell biology — Posted on 2024-07-24

1310 Synthetic dysmobility screening reveals a phosphorylation-independent facet of the SLK-Ezrin-F-actin signaling cascade.

LIN, H. C.; LIN, Y. Y.; WEI, L. Y.; ZHANG, J. M.; TSAI, P. J.; LIN, Y. C.; CHIA, J. S.; TSAI, F. C.

10.1101/2024.07.23.604488 — cell biology — Posted on 2024-07-24

1311 Solvatochromic reporter to image plasma membrane order leaflet by leaflet reveals ahighly asymmetric bilayer locally modulated by transbilayer interactions

Patra, C.; Samad, M.; van Zanten, T. S.; Singh, M.; Vishwakarma, R.; Pal Singh, P.; Mayor, S.

10.1101/2024.07.23.604763 — cell biology — Posted on 2024-07-24

1312 Coxsackievirus B infection invokes unique cell-type specific responses in primary human pancreatic islets

Veronese-Paniagua, D. A.; Hernandez-Rincon, D. C.; Taylor, J. P.; Tse, H. M.; Millman, J. R.

10.1101/2024.07.23.604861 — cell biology — Posted on 2024-07-24

1313 Sirt5 regulates chondrocyte metabolism and osteoarthritis development through protein lysine malonylation

Liu, H.; Binoy, A.; Ren, S.; Martino, T. C.; Miller, A. E.; Willis, C. R.; Veerabhadraiah, S. R.; Sukul, A.; Jurynec, M. J.; Zhu, S.

10.1101/2024.07.23.604872 — cell biology — Posted on 2024-07-24

1314 ATG9A and ARFIP2 cooperate to regulate PI4P levels for lysosomal repair

De Tito, S.; Almacellas, E.; Yu, D. D.; Zhang, W.; Millard, E.; Hervas, J. H.; Pellegrino, E.; Panagi, I.; Fodge, D.; Thurston, T. L. M.; Gutierrez, M.; Tooze, S.

10.1101/2024.07.23.604321 — cell biology — Posted on 2024-07-24

1315 Cell Storage Conditions Impact Single-Cell Proteomic Landscapes

Onat, B.; Momenzadeh, A.; Haghani, A.; Jiang, Y.; Song, Y.; Parker, S. J.; Meyer, J. G.

10.1101/2024.07.23.604834 — cell biology — Posted on 2024-07-24

1316 A systematic targeted genetic screen identifies proteins involved in cytoadherence of the malaria parasite P. falciparum.

Kuester, N.; Roling, L.; Ouayoue, A.; Steeg, K.; Przyborski, J. M.

10.1101/2024.07.24.604743 — cell biology — Posted on 2024-07-24

1317 Oestrogen influences B cell class-switching in individuals with an XX sex chromosome complement

Peckham, H.; Radziszewska, A.; de Gruijter, N. M.; Restuadi, R.; Kartawinata, M.; Robinson, G. A.; Martin-Gutierrez, L.; Deakin, C. T.; Wedderburn, L. R.; Jury, E. C.; Butler, G.; Rosser, E. C.; Ciurtin, C.

10.1101/2024.07.18.604160 — immunology — Posted on 2024-07-24

1318 Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during navigation in familiar and novel environments

Heer, C. M.; Sheffield, M. E. J.

10.1101/2023.11.29.569214 — neuroscience — Posted on 2024-07-24

1319 A Bayesian Solution to Count the Number of Molecules within a Diffraction Limited Spot

Hillsley, A.; Stein, J.; Tillberg, P. W.; Stern, D. L.; Funke, J.

10.1101/2024.04.18.590066 — biophysics — Posted on 2024-07-24

1320 A Lipid Atlas of the Human Kidney

Farrow, M. A.; Tideman, L. E. M.; Neumann, E. K.; Migas, L. G.; Patterson, N. H.; Colley, M. E.; Allen, J. L.; Pingry, E. L.; Dufresne, M.; Yang, H.; Brewer, M.; Rivera, E. S.; Romer, C. E.; Djambazova, K.; Sharman, K.; Kruse, A. R. S.; Gutierrez, D. B.; Harris, R. C.; Fogo, A. B.; de Caestecker, M. P.; Caprioli, R. M.; Van de Plas, R.; Spraggins, J. M.

10.1101/2022.04.07.487155 — biochemistry — Posted on 2024-07-24

1321 Evidence for homing behaviour consistent with path integration in Dascyllus trimaculatus

Murley, F.; Sibeaux, A.; Burt de Perera, T.

10.1101/2024.07.22.604582 — animal behavior and cognition — Posted on 2024-07-24

1322 A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.

Tesson, F.; Planel, R.; Egorov, A. A.; Georjon, H.; Vaysset, H.; Brancotte, B.; Neron, B.; Mordret, E.; Atkinson, G. C.; Bernheim, A.; Cury, J.

10.1101/2024.01.25.577194 — genomics — Posted on 2024-07-24

1323 Topological stress triggers persistent DNA lesions in ribosomal DNA with ensuing formation of PML-nucleolar compartment

Urbancokova, A.; Hornofova, T.; Novak, J.; Salajkova, S. A.; Stemberkova Hubackova, S.; Uvizl, A.; Buchtova, T.; Mistrik, M.; Mac Stay, B.; Hodny, Z.; Bartek, J.; Vasicova, P.

10.1101/2023.08.05.552131 — cell biology — Posted on 2024-07-24

1324 Pericytes promote more angiogenesis and vasculogenesis than mesenchymal stromal cells in microfluidic chips

Gonzalez-Rubio, J.; Kubiza, H.; Koenigs-Werner, H.; Jockenhoevel, S.; Cornelissen, C. G.; Thiebes, A. L.

10.1101/2023.11.02.565266 — cell biology — Posted on 2024-07-24

1325 N-terminal tags impair the ability of Lamin A to provide structural support to the nucleus

Odell, J.; Lammerding, J.

10.1101/2024.04.19.590311 — cell biology — Posted on 2024-07-24

1326 Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2

Xu, L.; Yu, D.; Xu, M.; Yang, L.-X.; Zou, Q.-C.; Feng, X.-L.; Li, M.-H.; Sheng, N.; Yao, Y.-G.

10.1101/2024.01.13.575537 — cell biology — Posted on 2024-07-24

1327 IncC plasmid genome rearrangements influence the vertical and horizontal transmission tradeoff in Escherichia coli

Allain, M.; Morel-Journel, T.; Condamine, B.; Gibeaux, B.; Gachet, B.; GSCHWIND, R.; Denamur, E.; Landraud, L.

10.1101/2024.04.17.589899 — microbiology — Posted on 2024-07-24

1328 Peptidoglycan-tethered and free forms of the Braun lipoprotein are in dynamic equilibrium in Escherichia coli

LIANG, Y.; HUGONNET, J.-E.; Rusconi, F.; Arthur, M.

10.1101/2023.09.26.559517 — microbiology — Posted on 2024-07-24

1329 Cryptococcosis, tuberculosis, and a kidney cancer fail to fit the atherosclerosis paradigm for foam cell lipid content

Guerrini, V.; Prideaux, B.; Khan, R.; Subbian, S.; Wang, Y.; Sadimin, E.; Pawar, S.; Ukey, R.; Singer, E. A.; Xue, C.; Gennaro, M. L.

10.1101/2023.06.08.542766 — immunology — Posted on 2024-07-24

1330 Synaptic weight dynamics underlying memory consolidation: implications for learning rules, circuit organization, and circuit function

Bhasin, B. J.; Raymond, J. L.; Goldman, M. S.

10.1101/2024.03.20.586036 — neuroscience — Posted on 2024-07-24

1331 Brain encoding of naturalistic, continuous, and unpredictable tactile events

Castellani, N.; Federici, A.; Fantoni, M.; Ricciardi, E.; Garbarini, F.; Bottari, D.

10.1101/2023.12.08.570756 — neuroscience — Posted on 2024-07-24

1332 Adolescent Alcohol Exposure Promotes Mechanical Allodynia and Alters Synaptic Function at Inputs from the Basolateral Amgydala to the Prelimbic Cortex

Obray, J. D.; Wilkes, E. T.; Scofield, M. D.; Chandler, L. J.

10.1101/2024.06.17.599360 — neuroscience — Posted on 2024-07-24

1333 Curvature coding in early visual system revealed by scale variance during adaptation to flashing circles

Nisar, I.; Elder, J. H.

10.1101/2023.02.11.528121 — neuroscience — Posted on 2024-07-24

1334 Automatic learning mechanisms for flexible human locomotion.

Rossi, C.; Leech, K.; Roemmich, R. T.; Bastian, A. J.

10.1101/2023.09.25.559267 — neuroscience — Posted on 2024-07-24

1335 TOR Inhibition Enhances Autophagic Flux and Immune Response in Tomato Plants Against PSTVd Infection

Silva, S.-V.; Prol, F. V.; Rodrigo, I.; Lison, P.; Belda Palazon, B.

10.1101/2024.07.11.603042 — plant biology — Posted on 2024-07-24

1336 Marangoni-like tissue flows enhance symmetry breaking of embryonic organoids

Gsell, S.; Tlili, S. L.; Merkel, M.; Lenne, P.-F.

10.1101/2023.09.22.559003 — biophysics — Posted on 2024-07-24

1337 PEG-mCherry interactions beyond classical macromolecular crowding

Haas-Neill, L.; Joron, K.; Lerner, E.; Rauscher, S.

10.1101/2024.05.07.592799 — biophysics — Posted on 2024-07-24

1338 Image-based force inference by biomechanical simulation

Vanslambrouck, M.; Thiels, W.; Vangheel, J.; van Bavel, C.; Smeets, B.; Jelier, R.

10.1101/2023.12.01.569682 — bioinformatics — Posted on 2024-07-24

1339 A generative foundation model for antibody sequence understanding

Barton, J.; Gaspariunas, A.; Yadin, D. A.; Dias, J.; Nice, F. L.; Minns, D. H.; Snudden, O.; Povall, C.; Valle Tomas, S.; Dobson, H.; Farmery, J. H.; Leem, J.; Galson, J. D.

10.1101/2024.05.22.594943 — bioinformatics — Posted on 2024-07-24

1340 Cryo-electron tomographic investigation of native hippocampal glutamatergic synapses

Matsui, A.; Spangler, C.; Elferich, J.; Shiozaki, M.; Jean, N.; Zhao, X.; Qin, M.; Zhong, H.; Yu, Z.; Gouaux, E.

10.1101/2024.04.01.587595 — biochemistry — Posted on 2024-07-24

1341 A map of canine sequence variation relative to a Greenland wolf outgroup

Nguyen, A.; Schall, P. Z.; Kidd, J. M.

10.1101/2024.06.03.597150 — genomics — Posted on 2024-07-24

1342 Chromosome-level reference genome assembly for the protected resource plant, Zenia insignis

Chen, S.-Y.; Yang, Z.-Y.; Zhang, R.; Liu, H.; Yi, T.-S.

10.1101/2024.06.01.596946 — genomics — Posted on 2024-07-24

1343 Bacillus toyonensis biovar Thuringiensis: an overlooked entomopathogen?

Sauka, D. H.; Del Valle, E. E.; Palma, L.

10.1101/2024.07.21.604280 — evolutionary biology — Posted on 2024-07-24

1344 Large language models overcome the challenges of unstructured text data in ecology

Castro, A.; Pinto, J.; Reino, L.; Pipek, P.; Capinha, C.

10.1101/2024.01.23.576654 — ecology — Posted on 2024-07-24

1345 Modeling foot-and-mouth disease dissemination in Brazil and evaluating the effectiveness of control measures

Cardenas, N.; Lopes, F.; Machado, G.

10.1101/2022.06.14.496159 — ecology — Posted on 2024-07-24

1346 Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis: Insights into tissue specialization and blastogenesis

Temiz, B.; Meier, M.; Wilson, M. J.

10.1101/2024.07.21.604516 — developmental biology — Posted on 2024-07-24

1347 Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

Laboy, R.; Ndoci, M.; Vonolfen, M.; Ballhysa, E.; syed, s. t.; droth, t.; schilling, k.; loehrke, a.; Atanassov, I.; Antebi, A.

10.1101/2023.06.14.544948 — cell biology — Posted on 2024-07-24

1348 Protrudin acts at ER-endosome contacts to promote KIF5-mediated endosomal fission and endosome-to-Golgi transport

Kleniuk, J.; Nadadhur, A. G.; Wolfenden, E.; Rodger, C.; Zlamalova, E.; Reid, E.

10.1101/2024.07.15.602703 — cell biology — Posted on 2024-07-24

1349 Identification of culturable fungi and bacteria in mosquito saliva and impact on arbovirus infection in vitro

Wang, L.; Remue, L.; Trappeniers, K.; Verwimp, S.; Adriaens, N.; Rivas, F.; Soto, A.; van Bree, J.; Garigliany, M.; Delang, L.

10.1101/2023.03.31.534949 — microbiology — Posted on 2024-07-24

1350 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge

Worrell, J. C.; Hargrave, K. E.; Finney, G. E.; Hansell, C.; Cole, J. J.; Singh Niijar, J.; Morton, F. R.; Pingen, M.; Purnell, T.; Mitchelson, K.; Brennan, E.; Allan, J.; Ilia, G.; Herder, V.; Kennedy Dietrich, C.; Doncheva, Y.; Jamieson, N.; MacLeod, M. K.

10.1101/2024.07.20.604410 — immunology — Posted on 2024-07-24

1351 UFMTrack: Under-Flow Migration Tracker enabling analysis of the entire multi-step immune cell extravasation cascade across the blood-brain barrier in microfluidic devices

Vladymyrov, M.; Marchetti, L.; Aydin, S.; Soldati, S. G. N.; Mossu, A.; Pal, A.; Gueissaz, L.; Ariga, A.; Engelhardt, B.

10.1101/2023.01.04.522827 — immunology — Posted on 2024-07-24

1352 A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

Le Pen, J.; Paniccia, G.; Kinast, V.; Moncada-Velez, M.; Ashbrook, A. W.; Bauer, M.; Hoffmann, H.- H.; Pinharanda, A.; Ricardo-Lax, I.; Stenzel, A. F.; Rosado-Olivieri, E. A.; Dinnon, K. H.; Doyle, W. C.; Freije, C. A.; Hong, S.-H.; Lee, D.; Lewy, T.; Luna, J. M.; Peace, A.; Schmidt, C.; Schneider, W. M.; Winkler, R.; Yip, E. Z.; Larson, C.; McGinn, T.; Menezes, M.-R.; Ramos-Espiritu, L.; Banerjee, P.; Poirier, J. T.; Sanchez-Rivera, F. J.; Zhang, Q.; Casanova, J.-L.; Carroll, T. S.; Glickman, J. F.; Michailidis, E.; Razooky, B.; MacDonald, M. R.; Rice, C. M.

10.1101/2024.02.16.580725 — immunology — Posted on 2024-07-24

1353 The noncoding circular RNA circHomer1 regulates developmental experience-dependent plasticity in mouse visual cortex

Jenks, K. R.; Cai, Y.; Nayan, M. E.; Tsimring, K.; Li, K.; Zepeda, J. C.; Heller, G. R.; Delepine, C.; Shih, J.; Yuan, S.; Zhu, Y.; Wang, Y.; Duan, Y.; Fu, A. K. Y.; Ku, T.; Yun, D. H.; Chung, K.; Zhang, C.; Boyden, E. S.; Mellios, N.; Sur, M.; Ip, J. P. K.

10.1101/2024.07.19.603416 — neuroscience — Posted on 2024-07-24

1354 Reduction in olfactory ability in aging Mitf mutant mice without neurodegeneration

Mechmet, F.; Petersen, P.; Steingrimsson, E.

10.1101/2024.06.24.600136 — neuroscience — Posted on 2024-07-24

1355 Prioritizing Maize Metabolic Gene Regulators through Multi-Omic Network Integration

Gomez-Cano, F. A.; Rodriguez, J.; Zhou, P.; Chu, Y.-H.; Magnusson, E.; Gomez-Cano, L.; Krishnan, A.; Springer, N. M.; de Leon, N.; Grotewold, E.

10.1101/2024.02.26.582075 — plant biology — Posted on 2024-07-24

1356 Deciphering drug response and phenotypic heterogeneity of cancer cells using gene ensembles of regulatory units defined by chromatin domains

Pandey, N.; Sharma, M.; Mathur, A.; Nzelu, G. A.; Hakimullah, M.; Jha, I. P.; Chandra, O.; Mishra, S.; Bhattacharya, J.; Sharma, A.; Foo, R.; Sandhu, K. S.; Mandoli, A.; DasGupta, R.; KUMAR, V.

10.1101/2023.01.15.524115 — cancer biology — Posted on 2024-07-24

1357 Improved differential expression analysis of miRNA-seq data by modeling competition to be counted

Jun, S.-H.; Halushka, M. K.; McCall, M.

10.1101/2024.05.07.592964 — bioinformatics — Posted on 2024-07-24

1358 Automated cell annotation in scRNA-seq data using unique marker gene sets

Nelson, T.; Thompson, G.

10.1101/2024.05.24.595477 — bioinformatics — Posted on 2024-07-24

1359 Noradrenergic and Dopaminergic Neural Correlates of Trait Anxiety: Unveiling the Impact of Maladaptive Emotion Regulation

Zareba, M. R.; Arino-Brana, P.; Pico-Perez, M.; Visser, M.

10.1101/2024.07.23.604801 — neuroscience — Posted on 2024-07-23

1360 Parabrachial CGRP neurons modulates conditioned active defensive behavior under a naturalistic threat

Pyeon, G. H.; Cho, H.; Chung, B. M.; Choi, J.-S.; Jo, Y. S.

10.1101/2024.07.23.604768 — neuroscience — Posted on 2024-07-23

1361 Personality development in wild house mice: Evidence for a nutrition-dependent sensitive period early in life

Walasek, N.; Jovicic, M.; Guenther, A.

10.1101/2024.07.23.604785 — animal behavior and cognition — Posted on 2024-07-23

1362 Paralemmin-1 controls the nanoarchitecture of the neuronal submembrane cytoskeleton

Macarron-Palacios, V.; Hubrich, J.; do Rego Barros Fernandes Lima, M. A.; Metzendorf, N. G.; Kneilmann, S.; Trapp, M.; Acuna, C.; Patrizi, A.; D'Este, E.; Kilimann, M. W.

10.1101/2024.07.23.604764 — cell biology — Posted on 2024-07-23

1363 Improved constructs for bait RNA display in a bacterial three-hybrid assay

Nguyen, L. D.; LeBlanc, H.; Berry, K. E.

10.1101/2024.07.23.604302 — molecular biology — Posted on 2024-07-23

1364 Virus-induced paraspeckle-like condensates are essential hubs for gene expression and their formation drives genomic instability

Harper, K. L.; Harrington, E. M.; Hayward, C.; Wongwiwat, W.; White, R. E.; Whitehouse, A.

10.1101/2024.07.23.604779 — microbiology — Posted on 2024-07-23

1365 QCM: real-time quantitative quality control of single-molecule localization microscopy acquisitions

MAILFERT, S.; DJENDLI, M.; FABRE, R.; Marguet, D. A.; Bertaux, N.

10.1101/2024.07.23.604731 — biophysics — Posted on 2024-07-23

1366 Induction of cytoplasmic dsDNA and cGAS-STING immune signaling after exposure of breast cancer cells to X-rays or high energetic carbon ions

Totis, C.; Averbeck, N. B.; Jakob, B.; Schork, M.; Volpi, G.; Hintze, D. F.; Durante, M.; Fournier, C.; Helm, A.

10.1101/2024.07.23.604756 — biophysics — Posted on 2024-07-23

1367 Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression

Yao, S.; Jeon, Y.; Kesner, B.; Lee, J. T.

10.1101/2024.07.23.604772 — genomics — Posted on 2024-07-23

1368 Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA

Megrian, D.; Martinez, M.; Alzari, P. M.; Wehenkel, A. M.

10.1101/2024.07.23.604723 — evolutionary biology — Posted on 2024-07-23

1369 A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase

Allan, L.; Corno, A.; Valverde, J. M.; Toth, R.; Ly, T.; Saurin, A. T.

10.1101/2024.07.23.604754 — cell biology — Posted on 2024-07-23

1370 Laue-DIALS: open-source software for polychromatic X-ray diffraction data

Hewitt, R. A.; Dalton, K. M.; Mendez, D.; Wang, H. K.; Klureza, M. A.; Brookner, D. E.; Greisman, J. B.; McDonagh, D.; Srajer, V.; Sauter, N. K.; Brewster, A. S.; Hekstra, D. R.

10.1101/2024.07.23.604358 — molecular biology — Posted on 2024-07-23

1371 The Molecular Evolution of the SARS-COV-2 Spike Protein: Study of Amino Acid Substitutions and Types

Moradian, M. M.; Baghoomian, A.; Sweredoski, M.; Ivan, T.; Ramjit, R.

10.1101/2024.07.22.604652 — molecular biology — Posted on 2024-07-23

1372 EMG1 methyltransferase activity regulates ribosome occupancy at viral uORFs

Harrington, E. M.; Murphy, J. C.; Aspden, J.; Whitehouse, A.

10.1101/2024.07.23.604771 — microbiology — Posted on 2024-07-23

1373 SARS-CoV-2 S, M and E Structural Proteins Down-modulate HIV-1 LTR Activity and Modulate Endoplasmic Reticulum Stress Responses

Albalawi, W.; Thomas, J.; Mughal, F.; Roper, K. J.; Alshehri, A.; Paxton, G.; Paxton, W. A.

10.1101/2024.07.23.604777 — immunology — Posted on 2024-07-23

1374 Computationally designed mRNA-launched protein nanoparticle vaccines

Hendricks, G. G.; Grigoryan, L.; Navarro, M. J.; Catanzaro, N. J.; Hubbard, M. L.; Powers, J. M.; Mattocks, M.; Treichel, C.; Walls, A. C.; Lee, J.; Ellis, D.; Wang, J. Y.; Cheng, S.; Miranda, M. C.; Valdez, A.; Chao, C. W.; Chan, S.; Men, C.; Johnson, M. R.; Hui, H.; Wu, S.-Y.; Lujan, V.; Muramatsu, H.; Lin, P. J. C.; Sung, M. M. H.; Tam, Y. K.; Leaf, E. M.; Pardi, N.; Baric, R. S.; Pulendran, B.; Veesler, D.; Schäfer, A.; King, N. P.

10.1101/2024.07.22.604655 — immunology — Posted on 2024-07-23

1375 The Impact of Preprints on the Citations of Journal Articles Related to COVID-19

Tsunoda, H.; Sun, Y.; Nishizawa, M.; Liu, X.; Amano, K.; Kominami, R.

10.1101/2024.07.21.604465 — scientific communication and education — Posted on 2024-07-23

1376 Identification of novel loci regulating dormancy in barley and association with hypoxia sensitivity

Farquharson, L. G. H.; Samanfar, B.; Khanal, R.; Bekele, W.; Brauer, E. K.

10.1101/2024.07.22.604677 — plant biology — Posted on 2024-07-23

1377 Early morphogenetic patterns of protonemata and gametophores of Physcomitrium patens (Hedw.) Mitt.

Raju, M. V. S.; Ashton, N. W.

10.1101/2024.07.22.604381 — plant biology — Posted on 2024-07-23

1378 PA2gamma promotes the malignant progression of tumor by elevating mitochondrial function via C1QBP

Wang, J.; Shi, Y.; Wang, Y.; Shen, Y.; Liu, H.; Sun, S.; Wang, Y.; Zhou, X.; Zhou, Y.; Zeng, X.; Li, J.; Chen, Q.

10.1101/2024.07.23.604769 — cancer biology — Posted on 2024-07-23

1379 Transformer Graph Variational Autoencoder for Generative Molecular Design

Nguyen, T.; Karolak, A.

10.1101/2024.07.22.604603 — biophysics — Posted on 2024-07-23

1380 Creating Coarse-Grained Systems with COBY: Towards Higher Accuracy in Membrane Complexity

Andreasen, M. D.; Souza, P. C. T.; Schott, B.; Zuzic, L.

10.1101/2024.07.23.604601 — biophysics — Posted on 2024-07-23

1381 Molecular Dynamics of Phosphatidylcholine Model Membranes of Splenic Lymphoma Cells

Kio, M.; Lucker, J.; Klauda, J. B.

10.1101/2024.07.23.604722 — biophysics — Posted on 2024-07-23

1382 Majority-LCL: Towards Malaria Cell Detection using Label Contrastive Learning and Majority voting Ensembling

Kundu, S.; Talukdar, R.; Roy, N.; Das, S.; Basu, S.; Mukhopadhyay, S.

10.1101/2024.07.22.604640 — bioinformatics — Posted on 2024-07-23

1383 Demultiplexing and barcode-specific adaptive sampling for nanopore direct RNA sequencing

van der Toorn, W.; Bohn, P.; Liu-Wei, W.; Olguin-Nava, M.; Smyth, R. P.; von Kleist, M.

10.1101/2024.07.22.604276 — bioinformatics — Posted on 2024-07-23

1384 Quantifying defective and wild-type viruses from high-throughput RNA sequencing

Munoz-Sanchez, J. C.; Olmo-Uceda, M. J.; Oteo, J. A.; Elena, S. F.

10.1101/2024.07.23.604773 — bioinformatics — Posted on 2024-07-23

1385 Pheno-morphological screening and acoustic sorting of 3D multicellular aggregates using drop millifluidics

Rembotte, L.; Beneyton, T.; Buisson, L.; Badon, A.; Boyreau, A.; Douillet, C.; Hermant, L.; Jana, A.; Nassoy, P.; Baret, J.-C.

10.1101/2024.07.22.604529 — bioengineering — Posted on 2024-07-23

1386 Bacterial cell cycle regulator MatP forms biomolecular condensates and directly interacts with cell division protein FtsZ

Barros-Medina, I.; Robles-Ramos, M. A.; Sobrinos-Sanguino, M.; Luque-Ortega, J. R.; Alfonso, C.; Margolin, W.; Rivas, G.; Monterroso, B.; Zorrilla, S.

10.1101/2024.07.23.604758 — biochemistry — Posted on 2024-07-23

1387 FAAH Inhibition as a Path to Mitigate Alzheimer's Disease Progression in Mouse Models of Amyloidosis

Oddi, S.; Scipioni, L.; Totaro, A.; Giacovazzo, G.; Ciaramellano, F.; Tortolani, D.; Leuti, A.; Businaro, R.; Armeli, F.; Bilkei-Gorzo, A.; Coccurello, R.; Zimmer, A.; Maccarrone, M.

10.1101/2024.07.23.604774 — biochemistry — Posted on 2024-07-23

1388 Unusual traits shape the architecture of the Ig ancestor molecule

Urdiciain, A.; Madej, T.; Wang, J.; Song, J.; Erausquin, E.; Youkharibache, P.; Lopez-Sagaseta, J.

10.1101/2024.07.22.604567 — evolutionary biology — Posted on 2024-07-23

1389 Red harvester ants (Pogonomyrmex barbatus) do not distinguish between sorghum head mold symptomatic and asymptomatic seeds

Elliott-Vidaurri, L. V.; Penn, H. J.; Choudhury, R. A.

10.1101/2024.07.22.604667 — ecology — Posted on 2024-07-23

1390 ASO-mediated knockdown of GPNMB in mutant-GRN and Grn-deficient peripheral myeloid cells disrupts lysosomal function and immune responses

Wallings, R.; Gillett, D. A.; Staley, H.; Mahn, S.; Mark, J.; Neighbarger, N.; kordasiewicz, H.; Hirst, W. D.; Tansey, M. G.

10.1101/2024.07.22.604676 — immunology — Posted on 2024-07-23

1391 Different timescales of neural activities introduce different representations of task-relevant information

Kurikawa, T.

10.1101/2024.07.23.604720 — neuroscience — Posted on 2024-07-23

1392 Constructing Ensemble Gene Functional Networks Capturing Tissue/condition-specific Co-expression from Unlabled Transcriptomic Data with TEA-GCN

Lim, P. K.; Wang, R.; Antony Velankanni, J. P.; Mutwil, M.

10.1101/2024.07.22.604713 — systems biology — Posted on 2024-07-23

1393 Interplay of Light, Melatonin, and Circadian Genes in Skin Pigmentation Regulation

Bertolesi, G. E.; Debnath, N.; Heshami, N.; Bui, R.; Zadeh-Haghighi, H.; Simon, C.; McFarlane, S.

10.1101/2024.07.22.604624 — physiology — Posted on 2024-07-23

1394 Anti-Tumor Potential of AEV01 in Glioma and Hepatocellular Carcinoma: In Vitro and Xenograft Model Studies.

T. S, A.; Biswas, I.; KUMAR, A.; MM, S.; Medasani, R.

10.1101/2024.07.22.604571 — cancer biology — Posted on 2024-07-23

1395 Cleavage region organizes the structural architecture of the B2 SINE ribozyme

Singhal, A.; Mrozowich, T.; Chaudhury, S. N.; Rivera, C.; Badmalia, M.; Lee, J. T.; Patel, T. R.; Sanbonmatsu, K.

10.1101/2024.07.22.604665 — biophysics — Posted on 2024-07-23

1396 RAF2Net: Automated grading of Renal cell Carcinoma utilizing Attention-enhanced deep learning models through Feature Fusion

Kundu, S.; Roy, N.; Talukdar, R.; Das, S.; Mukhopadhyay, S.; Basu Mallik, B.

10.1101/2024.07.22.604646 — bioinformatics — Posted on 2024-07-23

1397 High throughput method for simultaneous screening of membrane permeability and toxicity for discovery of new cryoprotective agents

Ahmadkhani, N.; Benson, J. D.; Eroglu, A.; Higgins, A. Z.

10.1101/2024.07.22.604685 — bioengineering — Posted on 2024-07-23

1398 Hexokinase-I directly binds to a charged membrane-buried glutamate of mitochondrial VDAC1 and VDAC2

Holthuis, J. C. M.; Bieker, S.; Timme, M.; Woge, N.; Hassan, D. G.; Brown, C. M.; Marrink, S.-J.; Melo, M. N.

10.1101/2024.07.22.604557 — biochemistry — Posted on 2024-07-23

1399 Graph-structured populations elucidate the role of deleterious mutations in long-term evolution

Sharma, N.; Das, S. G.; Krug, J.; Traulsen, A.

10.1101/2024.07.23.604724 — evolutionary biology — Posted on 2024-07-23

1400 Specialization restricts the evolutionary paths available to yeast sugar transporters

Crandall, J. G.; Zhou, X.; Rokas, A.; Hittinger, C. T.

10.1101/2024.07.22.604696 — evolutionary biology — Posted on 2024-07-23

1401 Murine aortic valve cell heterogeneity at birth

Lincoln, J.; Bluemn, T.; Kessler, J. R.; Kim, A. J.; Drnevich, J.

10.1101/2024.07.22.604705 — cell biology — Posted on 2024-07-23

1402 Metabolic profiling using benchtop NMR identifies the metabolomic signature of persistent CAR-T cells

Song, S.-H.; Ryan, H.; Hoefflin, J.; Kyung, T.; Mace, J.; Raman, J.; Eshghi, S.

10.1101/2024.07.22.604702 — cell biology — Posted on 2024-07-23

1403 Integrating in silico predictions with an engineered tissue assay identifies Perlecan as an age-perturbed re-quiescence cue for muscle stem cells

Jacques, E.; Garcia, P.; Mercier, O.; Hu, Y.; Degletagne, C.; Ravent, J.; Fall, S.; Almeida, M. P.; Wheeler, A. R.; Angers, S.; Gilbert, P. M.; Le Grand, F.

10.1101/2024.07.22.604619 — cell biology — Posted on 2024-07-23

1404 Cryptosporidium oocysts and Giardia cysts at two South African wastewater treatment plants

Gonose, T.; Du Preez, H.; Venter, S. N.; Grundlingh, M.

10.1101/2024.07.22.604670 — microbiology — Posted on 2024-07-23

1405 Transiently boosting Vγ9+Vδ2+ γδ T cells early in Mtb coinfection of SIV-infected juvenile macaques does not improve Mtb host resistance.

Larson, E. C.; Ellis, A.; Rodgers, M.; Gubernat, A. K.; Gleim, J. L.; Moriarty, R. V.; Balgeman, A. J.; Menezes, Y. K.; Ameel, C.; Fillmore, D. J.; Pergalske, S. M.; Juno, J. A.; Maiello, P.; Chishti, H. B.; Lin, P. L.; Godfrey, D. I.; Kent, S. J.; Pellicci, D.; NDHLOVU, L. C.; O'Connor, S. L.; Scanga, C. A.

10.1101/2024.07.22.604654 — immunology — Posted on 2024-07-23

1406 A Hypothalamic Circuit that Modulates Feeding and Parenting Behaviors

Alcantara, I. C.; Li, C.; Mickelsen, L. E.; Mazzone, C. M.; de Araujo Salgado, I.; Gao, C.; Papas, B. N.; Xiao, C.; Karolczak, E. O.; Goldschmidt, A. I.; Rodriguez Gonzalez, S.; Pinol, R. A.; Li, J.-L.; Cui, G.; Reitman, M. L.; Krashes, M. J.

10.1101/2024.07.22.604437 — neuroscience — Posted on 2024-07-23

1407 Enhanced restoration of visual code after targeting on bipolar cells compared to retinal ganglion cells with optogenetic therapy

Rodgers, J.; Hughes, S.; Ebrahimi, A.; Allen, A. E.; Storchi, R.; Lindner, M.; Peirson, S. N.; Badea, T. C.; Hankins, M. W.; Lucas, R. J.

10.1101/2024.07.22.604613 — neuroscience — Posted on 2024-07-23

1408 Bayesian Prior Uncertainty and Surprisal Elicit Distinct Neural Patterns During Sound Localization in Dynamic Environments

Bayram, B.; Meijer, D.; Barumerli, R.; Spierings, M.; Baumgartner, R.; Pomper, U.

10.1101/2024.07.22.604566 — neuroscience — Posted on 2024-07-23

1409 Sympathetic Nervous System Overactivation Induces Colonic Eosinophil-Associated Microinflammation and Contributes to the Pathogenesis of Irritable Bowel Syndrome

Duan, S.; Kanda, H.; Zhu, F.; Okubo, M.; Koike, T.; Ohno, Y.; Tanaka, T.; Harima, Y.; Miyamichi, K.; Fukui, H.; Shinzaki, S.; Cui, Y.; Noguchi, K.; Dai, Y.

10.1101/2024.07.22.604223 — neuroscience — Posted on 2024-07-23

1410 Brief sleep disruption alters synaptic structures among hippocampal and neocortical somatostatin-expressing interneurons

Raven, F.; Vega Medina, A.; Schmidt, K.; He, A.; Vankampen, A.; Balendran, V.; Aton, S. J.

10.1101/2024.07.22.604591 — neuroscience — Posted on 2024-07-23

1411 The Unity/Diversity Framework of Executive Functions in Older Adults

Guo, S.-J.; Wang, P.; Cao, L.-Z.; Li, H.-J.

10.1101/2024.07.22.604231 — neuroscience — Posted on 2024-07-23

1412 Control of cholesterol-induced adipocyte inflammation by the Nfe2l1-Atf3 pathway

Jethwa, C.; Hoffmann, A.; Kotschi, S.; Caesar, J.; Kern, M.; Worthmann, A.; Schlein, C.; Khani, S.; Arus, B. A.; Bruns, O. T.; Ghosh, A.; Wolfrum, C.; Döring, Y.; Herzig, S.; Weber, C.; Blüher, M.; Widenmaier, S. B.; Hotamıslıgil, G. S.; Bartelt, A.

10.1101/2024.07.22.604614 — physiology — Posted on 2024-07-23

1413 Impact of vertebrate host parasitaemia on Plasmodium development within mosquitoes

Isaia, J.; Baur, M.; Wassef, J.; Monod, S.; Glaizot, O.; Christe, P.; Pigeault, R.

10.1101/2024.07.22.604581 — pathology — Posted on 2024-07-23

1414 Preclinical Pediatric Molecular Analysis for Therapy Choice (MATCH)

Blankenship, K.; Chang, T.-C.; Fan, Y.; Gordon, B.; Wright, W. C.; Kieffer, M.; Karlstrom, A.; Jeon, J.; Patel, A.; Dapper, J.; Caufield, W. V.; Freeman, B. B.; Federico, S.; Clay, M. R.; Wu, G. G.; Zhou, X.; Hoffmann, L.; Geeleher, P.; Dyer, M. A.; McEvoy, J.; Stewart, E. A.

10.1101/2024.07.22.604648 — cancer biology — Posted on 2024-07-23

1415 Systematic profiling of the acetyl lysine machinery reveals a role for MAPKAPK2 in bromodomain inhibitor resistance

Kougnassoukou Tchara, P.-E.; Loehr, J.; Germain, L.; Steinhart, Z.; Gonzalez-Badillo, B.; Lashgari, A.; Chartier, F. J. M.; Tucholska, M.; Picaud, S.; Knight, J. D. R.; Angers, S.; Bisson, N.; Goding, C. R.; Audet-Walsh, E.; Filippakopoulos, P.; Gingras, A.-C.; Lambert, J.-P.

10.1101/2024.07.22.604604 — cancer biology — Posted on 2024-07-23

1416 Systematic Multi-Omics Investigation of Androgen Receptor Driven Gene Expression and Epigenetics changes in Prostate Cancer

Li, L.; Cho, K. H.; Yu, X.; Cheng, S.

10.1101/2024.07.22.604505 — cancer biology — Posted on 2024-07-23

1417 Sequence programmable nucleic acid coacervates

Majumder, S.; Coupe, S.; Fakhri, N.; Jain, A.

10.1101/2024.07.22.604687 — biophysics — Posted on 2024-07-23

1418 SOLeNNoID: A Deep Learning Pipeline For Solenoid Residue Detection in Protein Structures

Nikov, G. I.; Pretorius, D.; Murray, J. W.

10.1101/2024.07.22.604558 — bioinformatics — Posted on 2024-07-23

1419 Enhanced anti-tumor effects through continuous administration of engineered CAR-macrophages derived from pluripotent stem cell-derived myeloid celllines.

Atsumi, Y.; Niwa, A.; Kumaki, T.; Yagyu, S.; Nakazawa, Y.; Saito, M.

10.1101/2024.07.22.604686 — bioengineering — Posted on 2024-07-23

1420 Bacterial Wastewater-Based Epidemiology Using Surface-Enhanced Raman Spectroscopy and Machine Learning

Herndon, L. K.; Zhang, Y.; Safir, F.; Ogunlade, B.; Balch, H. B.; Boehm, A.; Dionne, J. A.

10.1101/2024.07.22.604506 — bioengineering — Posted on 2024-07-23

1421 Enabling Packaging Integration of Paper-based Electrical Gas Sensors for the Monitoring of Spoilage in Fresh Spinach

Naik, A.; Lee, H. S.; Herrington, J.; Barandun, G.; Flock, G.; Güder, F.; Gonzalez-Macia, L.

10.1101/2024.07.22.604629 — bioengineering — Posted on 2024-07-23

1422 STK19 positions TFIIH for cell-free transcription-coupled DNA repair

Mevissen, T. E. T.; Kuemmecke, M.; Schmid, E. W.; Farnung, L.; Walter, J. C.

10.1101/2024.07.22.604623 — biochemistry — Posted on 2024-07-23

1423 A spectrum of clinically-identified cysteine mutations in fibulin-3 (EFEMP1) highlight its disulfide bonding complexity and potential to induce stress response activation

Collier, G.; Hulleman, J.

10.1101/2024.07.22.604634 — biochemistry — Posted on 2024-07-23

1424 Highly ordered clustering of TNFα and BAFF ligand-receptor-adaptor complexes bound to lipid membranes

Lim, C. S.; Lee, J.; Kim, J. W.; Lee, J.-O.

10.1101/2024.07.22.604697 — biochemistry — Posted on 2024-07-23

1425 Boosting the Predictive Power of Protein Representations with a Corpus of Text Annotations

Duan, H.; Skreta, M.; Cotta, L.; Rajaonson, E. M.; Dhawan, N.; Aspuru-Guzik, A.; Maddison, C. J.

10.1101/2024.07.22.604688 — biochemistry — Posted on 2024-07-23

1426 A potent and selective reaction hijacking inhibitor of Plasmodium falciparum tyrosine tRNA synthetase exhibits single dose oral efficacy in vivo

Tilley, L.; Xie, S. C.; Tai, C.-W.; Morton, C. J.; Ma, L.; Huang, S.-C.; Wittlin, S.; Du, Y.; Hu, Y.; Dogovski, C.; Salimimarand, M.; Griffin, R.; England, D.; de la Curz, E.; Deni, I.; Yeo, T.; Burkhard, A. Y.; Striepen, J.; Schindler, K. A.; Crespo, B.; Gamo, F. J.; Khandokar, Y.; Hutton, C. A.; Rabie, T.; Birkholtz, L.-M.; Famodimu, M. T.; Delves, M. J.; Bolsher, J.; Koolen, K. M. J.; van der Laak, R.; Aguiar, A. C. C.; Pereira, D. B.; Creek, D. J.; Fidock, D. A.; Dick, L. R.; Brand, S. L.; Gould, A. E.; Langston, S.; Griffin, M. D. W.

10.1101/2024.07.22.604682 — biochemistry — Posted on 2024-07-23

1427 Parametrically guided design of beta barrels and transmembrane nanopores using deep learning

Kim, D. E.; Watson, J. L.; Juergens, D.; Majumder, S.; Gerben, S. R.; Kang, A.; Bera, A. K.; Li, X.; Baker, D.

10.1101/2024.07.22.604663 — biochemistry — Posted on 2024-07-23

1428 Evidence for homing behaviour consistent with path integration in Dascyllus trimaculatus

Murley, F.; Sibeaux, A.; Burt de Perera, T.

10.1101/2024.07.22.604582 — animal behavior and cognition — Posted on 2024-07-23

1429 Parallel selection in domesticated Atlantic salmon from divergent founders including parallel selection on WGD-derived homeologous regions

Buso, P.; Diblasi, C.; Manousi, D.; KWAK, J. S.; de Leon, A. V.-P.; Stenlokk, K.; Barson, N. J.; Saitou, M.

10.1101/2024.07.22.604627 — genomics — Posted on 2024-07-23

1430 Stimulation of locus coeruleus inputs to the frontal cortex in mice induces cell type-specific expression of the Apoe gene

Craig, G. E.; Ramos, L.; Essig, S. R.; Eagles, N. J.; Jaffe, A. E.; Martinowich, K.; Hallock, H. L.

10.1101/2024.07.22.604695 — genetics — Posted on 2024-07-23

1431 Genetic variants affect diurnal glucose levels throughout the day

Sinnott-Armstrong, N.; Strausz, S.; Urpa, L.; Abner, E.; Valliere, J.; Estonian Biobank Research Team, ; Palta, P.; Dashti, H. S.; Daly, M.; Pritchard, J. K.; Saxena, R.; Jones, S. E.; Ollila, H. M.

10.1101/2024.07.22.604631 — genetics — Posted on 2024-07-23

1432 Molecular and structural innovations of the stator motor complex at the dawn of flagellar motility

Puente-Lelievre, C.; Ridone, P.; Douglas, J.; Amritkar, K.; Kacar, B.; Baker, M. A.; Matzke, N. J.

10.1101/2024.07.22.604496 — evolutionary biology — Posted on 2024-07-23

1433 Convergent expansions of keystone gene families drive metabolic innovation in a major eukaryotic clade

David, K. T.; Schraiber, J. G.; Crandall, J. G.; LaBella, A. L.; Opulente, D. A.; Harrison, M.-C.; Wolters, J. F.; Zhou, X.; Shen, X.-X.; Groenewald, M.; Hittinger, C. T.; Pennell, M.; Rokas, A.

10.1101/2024.07.22.604484 — evolutionary biology — Posted on 2024-07-23

1434 Size evolution of gigantic genomes suggests stochastic outcomes of transposable element/host silencing interactions

Wang, J.; Zhang, G.; Sun, C.; Chang, L.; Wang, Y.; Yang, X.; Chen, G.; Itgen, M. W.; Haley, A.; Tang, J.; Mueller, R. L.

10.1101/2024.07.22.604708 — evolutionary biology — Posted on 2024-07-23

1435 Functional optimization in distinct tissues and conditions constrains the rate of protein evolution

Usmanova, D. R.; Plata, G.; Vitkup, D.

10.1101/2024.07.22.604632 — evolutionary biology — Posted on 2024-07-23

1436 Toward improved uncertainty quantification in predictions of forest dynamics: A dynamical model of forest change

Itter, M. S.; Finley, A. O.

10.1101/2024.07.22.604669 — ecology — Posted on 2024-07-23

1437 Trees as Reliable Carbon Capture and Storage in Urban Spaces: A Case Study in Kalaburagi, India

S K, S.; DJ, D.

10.1101/2024.07.22.604147 — ecology — Posted on 2024-07-23

1438 Relevance of the synergy of surveillance and populational networks in understanding the Usutu virus outbreak within common blackbirds (Turdus merula) in Metropolitan France, 2018

Bouchez-Zacria, M.; Calenge, C.; Villers, A.; Lecollinet, S.; Gonzalez, G.; Quintard, B.; Leclerc, A.; Baurier, F.; Paty, M.-C.; Faure, E.; Eraud, C.; Decors, A.

10.1101/2024.07.22.604715 — ecology — Posted on 2024-07-23

1439 Variability in honey bee cuticular hydrocarbon composition can be understood as a function of gene expression

Rodriguez-Leon, D. S.; Schmitt, T.; Pinto, M. A.; Thamm, M.; Scheiner, R.

10.1101/2024.07.22.604606 — ecology — Posted on 2024-07-23

1440 Non-floral scent sources of orchid bees: observations and significance

Henske, J.; De Dijn, B.; Eltz, T.

10.1101/2024.07.22.604569 — ecology — Posted on 2024-07-23

1441 Cell cycle-driven transcriptome maturation confers multilineage competence to cardiopharyngeal progenitors

Bernadskaya, Y. Y.; Kuan, A.; Tjarnberg, A.; Brandenburg, J.; Zheng, P.; Wiechecki, K.; Kaplan, N.; Failla, M.; Bikou, M.; Madilian, O.; Wang, W.; Christiaen, L.

10.1101/2024.07.23.604718 — developmental biology — Posted on 2024-07-23

1442 Localization of Drosophila formin, Cappuccino, influences posterior oocyte organization

Bailey, H. M.; Cullimore, P. B. M.; Bailey, L. A.; Quinlan, M. E.

10.1101/2024.07.22.604638 — developmental biology — Posted on 2024-07-23

1443 Impaired fatty acid import or catabolism in macrophages restricts intracellular growth of Mycobacterium tuberculosis

Simwela, N. V.; Jaecklein, E.; Sassetti, C. M.; Russell, D. G. M.

10.1101/2024.07.22.604660 — microbiology — Posted on 2024-07-23

1444 Aerobic methane production by methylotrophic Methylotenera in groundwater

Li, S.; Dong, X.; Humez, P.; Borecki, J.; Birks, J.; McClain, C.; Mayer, B.; Strous, M.; Diao, M.

10.1101/2024.07.22.604536 — microbiology — Posted on 2024-07-23

1445 Dietary iron deficiency impairs effector function of memory T cells following influenza infection

Bradley, M. C.; Gray, J.; La Carpia, F.; Idzikowski, E.; Guyer, R.; Pethe, K.; Hod, E.; Connors, T. J.

10.1101/2024.07.22.604599 — immunology — Posted on 2024-07-23

1446 Leveraging multivariate information for community detection in functional brain networks

Puxeddu, M. G.; Pope, M.; Varley, T. F.; Faskowitz, J.; Sporns, O.

10.1101/2024.07.22.604675 — neuroscience — Posted on 2024-07-23

1447 The timing of preceding tactile inputs modulates cortical processing

Wan, W.; Ridderinkhof, K. R.; Ghosh, A.

10.1101/2024.07.22.604577 — neuroscience — Posted on 2024-07-23

1448 Nanoscale organization is changed in native, surface AMPARs by mouse brain region and tauopathy

Vaidya, R. M.; Zhang, J.; Nall, D.; Lee, Y.; Kim, E. C.; Ma, D.; Huang, F.; Nonaka, H.; Kiyonaka, S.; Hamachi, I.; Chung, H. J.; Selvin, P. R.

10.1101/2024.07.22.604547 — neuroscience — Posted on 2024-07-23

1449 Secretome analysis of oligodendrocytes and precursors reveals their roles as contributors to the extracellular matrix and potential regulators of inflammation

Godoy, M. I.; Pandey, V.; Wohlschlegel, J. A.; Zhang, Y.

10.1101/2024.07.22.604699 — neuroscience — Posted on 2024-07-23

1450 Neural microstates in real-world behaviour captured on the smartphone

Kock, R.; Ghosh, A.

10.1101/2024.07.22.604605 — neuroscience — Posted on 2024-07-23

1451 Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation.

Martinez, P.; Jury-Garfe, N.; Patel, H.; You, Y.; Perkins, A.; You, Y.; Lee-Gosselin, A.; Vidal, R.; Lasagna-Reeves, C. A.

10.1101/2024.07.22.604618 — neuroscience — Posted on 2024-07-23

1452 A disinhibitory basal forebrain to cortex projection supports sustained attention

Li, S.-J.; Hangya, B.; Gupta, U.; Fischer, K. B.; Sturgill, J. F.; Callaway, E. M.; Kepecs, A.

10.1101/2024.07.22.604711 — neuroscience — Posted on 2024-07-23

1453 Arabidopsis NIM1-INTERACTING1 (NIMIN1) is a multi-domain protein controlling transition from systemic acquired resistance (SAR) to cell death

Saur, M.; Steilner, K.; Masroor, A.; Hubel, P.; Pfitzner, A. J. P.; Pfitzner, U. M.

10.1101/2024.07.22.604541 — plant biology — Posted on 2024-07-23

1454 Multi trait assessment of wheat variety mixtures performance and stability: mixtures for the win!

Stefan, L.; Strebel, S.; Camp, K.-H.; Christinat, S.; Fossati, D.; Staedeli, C.; Levy Haener, L.

10.1101/2024.07.22.604587 — plant biology — Posted on 2024-07-23

1455 Linking stomatal size and density to water use efficiency and leaf carbon isotope ratio in juvenile and mature trees

Petrik, P.; Petek-Petrik, A.; Lamarque, L. J.; Waite, P.-A.; Link, R. M.; Ruehr, N. K.; Schuldt, B.; Maire, V.

10.1101/2024.07.22.604523 — plant biology — Posted on 2024-07-23

1456 Off-the-shelf image analysis models outperform human visual assessment in identifying genes controlling seed color variation in sorghum

Shrestha, N.; Mangal, H.; Torres-Rodriguez, J. V.; Tross, M. C.; Lopez-Corona, L.; Linders, K.; Sun, G.; Mural, R. V.; Schnable, J. C.

10.1101/2024.07.22.604683 — plant biology — Posted on 2024-07-23

1457 Arterial arcades and collaterals regress under hemodynamics-based diameteradaptation: a computational and mathematical analysis

Rottschsfer, V.; Kuppers, W. G. N.; Chen, J.; van Bavel, E.

10.1101/2024.07.22.604568 — physiology — Posted on 2024-07-23

1458 Protein restriction associated with high fat induces metabolic dysregulation without obesity in juvenile mice

Joly, A.; Thoumas, J.-L.; Lambert, A.; Leulier, F.; De Vadder, F.

10.1101/2024.07.22.604540 — physiology — Posted on 2024-07-23

1459 Investigating the temporal effects of ovarian failure on single muscle fibre contractility using a chemically-induced ovarian failure model in mice

Mashouri, P.; Saboune, J.; Pyle, W. G.; Power, G. A.

10.1101/2024.07.22.604625 — physiology — Posted on 2024-07-23

1460 The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization

Hanif, S. Z.; Au, C. C.; Torregroza, I.; Jannath, S.; Fabiha, T.; Bhinder, B.; Washburn, M.; Devost, D.; Liu, S.; Bhardwaj, P.; Evans, T.; Anand, P. K.; Tarran, R.; Palikhe, S.; Elemento, O.; Dow, L. E.; Blenis, J.; Hebert, T.; Brown, K. A.

10.1101/2024.07.22.604482 — cancer biology — Posted on 2024-07-23

1461 Nuclease-Resistant L-DNA Tension Probes Enable Long-TermForce Mapping of Single Cells and Cell Consortia

Sethi, S.; Xu, T.; Sarkar, A.; Drees, C.; Jacob, C.; Walther, A.

10.1101/2024.07.22.604597 — biophysics — Posted on 2024-07-23

1462 Sensitive Detection of Structural Differences using a Statistical Framework for Comparative Crystallography

Hekstra, D. R.; Wang, H. K.; Klureza, M. A.; Greisman, J. B.; Dalton, K. M.

10.1101/2024.07.22.604476 — biophysics — Posted on 2024-07-23

1463 Transient Non-local Interactions Dominate the Dynamics of Measles Virus NTAIL

Otteson, L.; Nagy, G.; Kunkel, J.; Kodis, G.; Zheng, W.; Bignon, C.; Longhi, S.; Grubmüller, H.; Vaiana, A. C.; Vaiana, S. M.

10.1101/2024.07.22.604679 — biophysics — Posted on 2024-07-23

1464 Dynamic B0 field shimming for improving pseudo-continuous arterial spin labeling at 7 Tesla

Ji, Y.; Woods, J.; Li, H.; Okell, T. W.

10.1101/2024.07.22.604544 — biophysics — Posted on 2024-07-23

1465 dsRNAEngineer: a web-based tool of comprehensive dsRNA design for pest control

Chen, Y.; Shi, Y.; Wang, Z.; An, X.; Wei, S.; Andronis, C.; Vontas, J.; Wang, J.-j.; Niu, J.

10.1101/2024.07.22.604585 — bioinformatics — Posted on 2024-07-23

1466 Prediction of plant resistance proteins using alignment-based and alignment-free approaches

Gahlot, P. S.; Choudhury, S.; Bajiya, N.; Kumar, N.; Raghava, G. P. S.

10.1101/2024.07.22.604583 — bioinformatics — Posted on 2024-07-23

1467 FuncFetch: An LLM-assisted workflow enables mining thousands of enzyme-substrate interactions from published manuscripts

Smith, N.; Yuan, X.; Melissinos, C.; Moghe, G.

10.1101/2024.07.22.604620 — bioinformatics — Posted on 2024-07-23

1468 Confidence-Enhanced Semi-supervised Learning for Mediastinal Neoplasm Segmentation

Fu, X.; Zhang, S.; Zhou, J.; Ji, Y.

10.1101/2024.07.22.604560 — bioengineering — Posted on 2024-07-23

1469 Engineered microvasculature using maskless photolithography and on-chip hydrogel patterning: a facile approach

Kasi, D. G.; de Graaf, M. N. S.; Nahon, D. M.; van den Hil, F. E.; van den Maagdenberg, A. M. J. M.; Mummery, C. L.; Orlova, V. V.

10.1101/2024.07.22.604661 — bioengineering — Posted on 2024-07-23

1470 Epigenetic Dynamics in Meniscus Cell Migration and its Zonal Dependency in Response to Inflammatory Conditions: Implications for Regeneration Strategies

Zhang, Y.; Zhang, Y.; Wang, C.; Heo, Y.; Tumenbayar, B.-I.; Lee, S.-H.; Bae, Y.; Heo, S. C.

10.1101/2024.07.22.604178 — bioengineering — Posted on 2024-07-23

1471 The structure of full-length AFPK supports the ACP linker in a role that regulates iterative polyketide and fatty acid assembly

Schubert, H.; Li, F.; Hill, C.; Schmidt, E.

10.1101/2024.07.22.604177 — biochemistry — Posted on 2024-07-23

1472 Long-distance gene flow and recombination shape the evolutionary history of a maize pathogen

Rogerio, F.; Oosterhout, C. V.; De Mita, S.; Cuevas-Fernandez, F. B.; Garcia-Rodriguez, P.; Becerra, S.; Gutierrez-Sanchez, S.; Jacquat, A. G.; Bettiol, W.; Hosaka, G. K.; Ulla, S. B.; Hiltbrunner, J.; Santiago, R.; Revilla, P.; Dambolena, J. S.; Vicente-Villardon, J. L.; Buhinicek, I.; Sukno, S. A.; Thon, M. R.

10.1101/2024.07.22.604531 — genomics — Posted on 2024-07-23

1473 Population genetic structure of the aphid pest Myzus persicae in organic and conventional greenhouses

Beekman, M. M.; van den Heuvel, J.; Donner, S. H.; Litjens, J. J. H.; Dicke, M.; Zwaan, B. J.; Verhulst, E. C.; Pannebakker, B. A.

10.1101/2024.07.22.604537 — genetics — Posted on 2024-07-23

1474 Glycaemia and albumin glycation rates as fitness mediators in the wild: the case of a long-lived bird

Moreno Borrallo, A.; Bize, P.; Jaramillo Ortiz, S.; Schaeffer-Reiss, C.; Bertile, F.; Criscuolo, F.

10.1101/2024.07.22.604617 — evolutionary biology — Posted on 2024-07-23

1475 Drivers of temporal bias in biodiversity recording by citizen scientists

Rosario, I.; Tiago, P.; Chozas, S.; Capinha, C.

10.1101/2024.07.22.604598 — ecology — Posted on 2024-07-23

1476 Operational lessons learned from simulating an elimination response to a transboundary animal disease in wild animals

Chalkowski, K.; Pepin, K. M.; Lavelle, M. J.; Miller, R. S.; Fischer, J. W.; Brown, V. R.; Glow, M. P.; Smith, B.; Cook, S.; Kohen, K.; Sherburne, S.; Smith, H.; Leland, B. R.; VerCauteren, K. C.; Snow, N. P.

10.1101/2024.07.22.604666 — ecology — Posted on 2024-07-23

1477 A novel bifunctional peptide VAMP mined from hemp seed protein hydrolysates improves glucose homeostasis by inhibiting intestinal DPP-IV and increasing the abundance of Akkermansia muciniphila

Chen, H.; Li, W.; Hu, W.; Xu, B.; Wang, Y.; Liu, J.; Zhang, C.; Zhang, C.; Zhang, X.; Nie, Q.; Xing, X.-H.

10.1101/2024.07.22.604525 — molecular biology — Posted on 2024-07-23

1478 Sputum Proteomics reveals unique signatures linked to key outcomes in cystic fibrosis trials.

Pottenger, S.; Nazareth, D.; Wat, D.; Bellina, B.; Langini, M.; Walshaw, M.; Neill, D. R.; Schwarz, C.; Frost, F.; Fothergill, J. L.

10.1101/2024.07.23.604741 — immunology — Posted on 2024-07-23

1479 Trait anxiety impairs reciprocity behavior: A multi-modal and computational modeling study

Fang, H.; Wang, R.; Wang, Z.; Liu, Q.; Xu, P.; Luo, Y.; Krueger, F.

10.1101/2024.07.21.604469 — neuroscience — Posted on 2024-07-23

1480 Who Grows There? A Course-based Undergraduate Research Experience to explore the human microbiome through 16S DNA metabarcoding

Sellers, G. S.; Freiheit, M.; Winter, M. R.; Joyce, D.; Cullen, D.; Lunt, D. H.; Hubbard, K.

10.1101/2024.07.22.600610 — scientific communication and education — Posted on 2024-07-23

1481 Experimentally induced pain and paresthesia respond differently to cuff-based compression

Skalski, J.; Swoboda, S.; Szikszay, T.; Wodarski, P.; Bieniek, A.; Luedtke, K.; Adamczyk, W. M.

10.1101/2024.07.22.604622 — physiology — Posted on 2024-07-23

1482 DriverOmicsNet: An Integrated Graph Convolutional Network for Multi-Omics Exploration of Cancer Driver Genes

Dai, Y.-H.; Chang, C.-J.; Shen, P.-C.; Jheng, W.-L.; Chen, Y.-G.

10.1101/2024.07.21.604474 — cancer biology — Posted on 2024-07-23

1483 The Physical Basis of Osmosis in a Donnan Ionic System

Manning, G. S.

10.1101/2024.07.22.604593 — biophysics — Posted on 2024-07-23

1484 Feature Importance in Predicting Clinical Outcome: Statistics vs. Explainable Artificial Intelligence

Amin, P.

10.1101/2024.07.21.604467 — bioinformatics — Posted on 2024-07-23

1485 An Open-Set Semi-Supervised Multi-Task Learning Framework for Context Classification in Biomedical Texts

Tang, D.; Tam, T. Y. C.; Miskov-Zivanov, N.

10.1101/2024.07.22.604491 — bioinformatics — Posted on 2024-07-23

1486 The Identification Markers of activated myofibroblast subsets in the Human Lung Fibrosis Ecosystem via integrated omics Analysis

Zheng, Y.; Song, Z.; Li, S.; Cao, B.; Wu, H.

10.1101/2024.07.21.604481 — bioinformatics — Posted on 2024-07-23

1487 A new trait in a well-studied ant: low aggression between workers from Lasius niger (Hymenoptera, Formicidae) nest complexes

Stukalyuk, S.

10.1101/2024.07.23.604725 — ecology — Posted on 2024-07-23

1488 An arylsulphonamide that targets cell wall biosynthesis in Mycobacterium tuberculosis

Allen, R.; Ames, L.; Baldin, V. P.; Butts, A.; Henry, K. J.; Quach, D.; Sugie, J.; Pogliano, J.; Parish, T.

10.1101/2024.07.22.604653 — microbiology — Posted on 2024-07-23

1489 Recent odor experience selectively modulates olfactory sensitivity across the glomerular output in the mouse olfactory bulb

Subramanian, N.; Leong, L. M.; Salemi Mokri Boukani, P.; Storace, D. A.

10.1101/2024.07.21.604478 — neuroscience — Posted on 2024-07-23

1490 Stiffness-tunable neurotentacles for minimally invasive implantation and long-term neural activity recordings

Wang, Y.; Xu, X.; Yang, X.; Tang, R.; Chen, Y.; Wang, Y.; Liang, J.; Pei, W.

10.1101/2024.07.21.604464 — neuroscience — Posted on 2024-07-23

1491 Reduced learning rate and E/I imbalance drive Peripersonal Space boundaries expansion in Schizophrenia

Paredes, R.; Grigoras, V.; Ferroni, F.; Ardizzi, M.; Ferri, F.; Series, P.

10.1101/2024.07.21.604515 — neuroscience — Posted on 2024-07-23

1492 Synapse protein signatures in cerebrospinal fluid and plasma predict cognitive maintenance versus decline in Alzheimers disease

Oh, H. S.-H.; Urey, D. Y.; Karlsson, L.; Zhu, Z.; Shen, Y.; Farinas, A.; Timsina, J.; Guldner, I. H.; Morshed, N.; Yang, C.; Western, D.; Ali, M.; Le Guen, Y.; Trelle, A.; Herukka, S.-K.; Rauramaa, T.; Hiltunen, M.; Lipponen, A.; Luikku, A. J.; Poston, K. L.; Mormino, E.; Wagner, A. D.; Wilson, E. N.; Channappa, D.; Leinonen, V.; Stevens, B.; Ehrenberg, A. J.; Zetterberg, H.; Bennett, D. A.; Franzmeier, N.; Hansson, O.; Cruchaga, C.; Wyss-Coray, T.

10.1101/2024.07.22.604680 — neuroscience — Posted on 2024-07-23

1493 IGLoo: Profiling the Immunoglobulin Heavy chain locus in Lymphoblastoid Cell Lines with PacBio High-Fidelity Sequencing reads

Lin, M.-J.; Langmead, B.; Safonova, Y.

10.1101/2024.07.20.604421 — genomics — Posted on 2024-07-23

1494 Functional gene embeddings improve rare variant polygenic risk scores

Londhe, S.; Lindner, J.; Chen, Z.; Holtkamp, E.; Holzlwimmer, F. R.; Casale, F. P.; Brechtmann, F.; Gagneur, J.

10.1101/2024.07.22.604535 — genetics — Posted on 2024-07-23

1495 Long shared haplotypes identify the Southern Urals as a primary source for the 10th century Hungarians

Gyuris, B.; Vyazov, L.; Türk, A.; Flegontov, P.; Szeifert, B.; Lango, P.; Mende, B. G.; Csaky, V.; Chizhevskiy, A. A.; Gazimzyanov, I. R.; Khokhlov, A. A.; Kolonskikh, A. G.; Matveeva, N. P.; Ruslanova, R. R.; Rykun, M. P.; Sitdikov, A.; Volkova, E. V.; Botalov, S. G.; Bugrov, D. G.; Grudochko, I. V.; Komar, O.; Krasnoperov, A. A.; Poshekhonova, O. E.; Chikunova, I.; Sungatov, F.; Stashenkov, D. A.; Zubov, S.; Zelenkov, A. S.; Ringbauer, H.; Cheronet, O.; Pinhasi, R.; Akbari, A.; Rohland, N.; Mallick, S.; Reich, D.; Szecsenyi-Nagy, A.

10.1101/2024.07.21.599526 — genetics — Posted on 2024-07-23

1496 Queen number shapes worker longevity, fecundity and gene expression in the invasive, highly polygynous ant Tapinoma magnum

Lenhart, A.; Majoe, M.; Selvi, S.; Colgan, T. J.; Libbrecht, R.; Foitzik, S.

10.1101/2024.07.21.604453 — evolutionary biology — Posted on 2024-07-23

1497 Pollen Trapping As Honeybees Pollination Management and Identification of Dominant Pollinators of Guizotia abyssinica (L.f)

Jilo, K. R.; Yadeta, G. L.; Gemmeda, T. K.

10.1101/2024.07.21.604512 — evolutionary biology — Posted on 2024-07-23

1498 Range geographies, not functional traits, explain convergent range and phenology shifts under climate change

Sirois-Delisle, C.; Gordon, S. C. C.; Kerr, J.

10.1101/2024.07.22.604548 — ecology — Posted on 2024-07-23

1499 Dengue virus structural proteins are expressed on the surface of DENV-infected cells and are a target for antibody-dependent cellular phagocytosis

Waldran, M. J.; Kurtz, E. A.; Gebo, C. J.; Rooney, T. J.; Middleton, F. A.; Roy, N. H.; Currier, J. R.; Waickman, A. T.

10.1101/2024.07.21.604479 — immunology — Posted on 2024-07-23

1500 Inhibiting monocyte migration reduces arterial thrombosis and facilitates thrombolysis

JANG, H. J.; Kim, J.; Kim, H.; Chung, J.; Kim, T.; Cremer, S.; Krohn-Grimberghe, M.; Schellingerhout, D.; Nahrendorf, M.; Kim, D.-E.

10.1101/2024.07.21.604499 — immunology — Posted on 2024-07-23

1501 Disposition of the chemosensory neurons in the neurotransmitter-release mutant unc-13

Bokman, E.; Zaslaver, A.

10.1101/2024.07.21.604457 — neuroscience — Posted on 2024-07-23

1502 Characterizing the heterogeneity of neurodegenerative diseases through EEG normative modeling

HASSAN, M.; Tabbal, J.; Ebadi, A.; Mheich, A.; Kabbara, A.; Guntekin, B.; Yener, G.; Paban, V.; Gschwandtner, U.; Fuhr, P.; Verin, M.; Babiloni, C.; Allouch, S.

10.1101/2024.07.22.604542 — neuroscience — Posted on 2024-07-23

1503 Neurotoxic Methamphetamine Doses Alter CDCel-1 Levels and Its Interaction with Vesicular Monoamine Transporter-2 in Rat Striatum

Chauhan, H.; Carruthers, N.; Stemmer, P.; Schenider, B.; Moszczynska, A.

10.1101/2024.07.21.604458 — neuroscience — Posted on 2024-07-23

1504 Patterns of Ongoing Thought in the Real World and Their Link to Mental Health and Well-Being

Mulholland, B.; Chitiz, L.; Wallace, R.; Mckeown, B.; Milham, M.; Klein, A.; Leech, R.; Jefferies, E.; Poerio, G.; Wammes, J.; Smallwood, J.

10.1101/2024.07.22.604681 — neuroscience — Posted on 2024-07-23

1505 ERβ mediates sex-specific protection in the App-NL-G-F mouse model of Alzheimer's disease

Demetriou, A.; Lindqvist, B.; Ali, H. G.; Shamekh, M. M.; Maioli, S.; Inzunza, J.; Varshney, M.; Nalvarte, I.

10.1101/2024.07.22.604543 — neuroscience — Posted on 2024-07-23

1506 TDSTDP

Liu, B.

10.1101/2024.07.21.604454 — neuroscience — Posted on 2024-07-23

1507 Plant volatile-based fumigation improves mating competitiveness of males for population suppression of the global fruit pest Cydia pomonella

Huang, S.-W.; Wang, P.-C.; Wang, Y.; Wang, J.-Q.; Gao, P.; Yang, X.

10.1101/2024.07.21.604520 — zoology — Posted on 2024-07-23

1508 A Suite of Biochemical and Cell-Based Assays for the Characterization of KRAS Inhibitors and Degraders

Kidane, M.; Hoffman, R. M.; Wolfe-Demarco, J. K.; Huang, T.-Y.; Teng, C.-L.; Gonzalez Lira, L. M.; Lin-Jones, J.; Pallares, G.; Lamerdin, J. E.; Servant, N. B.; Lee, C.-Y.; Yang, C.-T.; Bernatchez, J. A.

10.1101/2024.07.20.604418 — pharmacology and toxicology — Posted on 2024-07-23

1509 A Molecular Image-based Explainable Artificial intelligence Framework Identifies Novel Candidate Antibiotics

Lin, K.; Yang, Y.; Cheng, F.

10.1101/2024.07.21.604494 — pharmacology and toxicology — Posted on 2024-07-23

1510 The multifaceted process of human coronary atherosclerotic cap destabilisation

Bruijn, L. E.; Fonseca Neves, N.; van Rhijn, C. M.; Hamming, J.; van den Bogaerdt, A.; Lindeman, J.

10.1101/2024.07.21.604507 — pathology — Posted on 2024-07-23

1511 An extinct clade sister to Eumetazoa: On the phylogeny of the Cambrian chancelloriids

Yun, H.; Zhang, X.; Brock, G. A.; Han, J.; Li, L.; Pan, B.; Li, G.; Reitner, J.

10.1101/2024.07.22.604532 — paleontology — Posted on 2024-07-23

1512 Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HSNCC

Abdelazeem, K. N. M.; Nguyen, D.; Corbo, S.; Darragh, L.; Matsumoto, M. W.; Vancourt, B.; Neupert, B.; Yu, J.; Olimpo, N.; Osborne, D. G.; Gadwa, J.; Ross, R. B.; Nguyen, A.; Bhatia, S.; Kapoor, M.; Friedman, R. S.; Jacobelli, J.; Saviola, A. J.; Knitz, M. W.; Pasquale, E. B.; Karam, S. D.

10.1101/2024.07.21.604518 — cancer biology — Posted on 2024-07-23

1513 GRATCR: epitope-specific T cell receptor sequence generation with data-efficient pre-trained models

Zhou, Z.; Chen, J.; Lin, S.; Hong, L.; Wei, D.-Q.; Xiong, Y.

10.1101/2024.07.21.604503 — bioinformatics — Posted on 2024-07-23

1514 AI-assisted In-silico Trial for the Optimization of Osmotherapy following Ischaemic Stroke

chen, x.; Lu, L.; Jozsa, T. I.; Clifton, D.; Payne, S.

10.1101/2024.07.20.604439 — bioengineering — Posted on 2024-07-23

1515 Continuous Monitoring of Glucose and Oxygen using an Insertable Biomaterial-based Multianalyte Barcode Sensor

Pradhan, R.; Chimene, D.; Ko, B. S.; Goncharov, A.; Ozcan, A.; McShane, M. J.

10.1101/2024.07.21.604502 — bioengineering — Posted on 2024-07-23

1516 Cannabidiol reverses fentanyl-induced addiction and modulates neuroinflammation

Bhandari, B.; Chagas, H. I. S.; Naeini, S. E.; Chagas, P. S.; Rogers, H. M.; Gouron, J.; Khan, A.; Maciel, L. M.; Seyyedi, M.; MacKinnon, N. J.; Khodadadi, H.; Salles, E. L.; Hess, D. C.; Morgan, J. C.; Yu, J. C.; Wang, L. P.; Baban, B.

10.1101/2024.07.20.604441 — animal behavior and cognition — Posted on 2024-07-23

1517 Landing on a dime: the biomechanics and kinematics of lovebirds (Agapornis roseicollis) landing on a swinging perch

Bhagavatula, P. S.; Biewener, A. A.

10.1101/2024.07.21.604435 — animal behavior and cognition — Posted on 2024-07-23

1518 Telomere-to-telomere sheep genome assembly reveals new variants associated with wool fineness trait

Luo, L.-Y.; Wu, H.; Zhao, L.-M.; Zhang, Y.-H.; Huang, J.-H.; Liu, Q.-Y.; Wang, H.-T.; Mo, D.-X.; EEr, H.-H.; Zhang, L.-Q.; Chen, H.-L.; Jia, S.-G.; Wang, W.-M.; Li, M.-H.

10.1101/2024.07.21.604451 — genomics — Posted on 2024-07-23

1519 Click-chemistry-aided quantitation and sequencing of oxidized guanines and apurinic sites uncovers their transcription-linked strand bias in human cells

Takhaveev, V.; Püllen, N. J. L.; Singh, N. K.; Huber, S. M.; Schauer, S.; Gahlon, H. L.; Poetsch, A. R.; Sturla, S. J.

10.1101/2024.07.21.604463 — genomics — Posted on 2024-07-23

1520 The role of methylation and structural variants in shaping the recombination landscape of barley

Casale, F. A.; Arlt, C.; Kuehl, M.; Li, J.; Engelhorn, J.; Hartwig, T.; Stich, B.

10.1101/2024.07.22.604552 — genomics — Posted on 2024-07-23

1521 Relative fire-proneness of land cover types in the Brazilian Atlantic Forest

Adorno, B. F.; Piratelli, A. A.; Hasui, E.; Ribeiro, M. C.; Vaz, P. G.

10.1101/2024.07.21.604452 — ecology — Posted on 2024-07-23

1522 Is there a negative trend in abundance of the weedyseadragon (Phyllopteryx taeniolatus) discernible in survey data summarised in Edgar et al. (2023)?

Schlögl, E.; Booth, D.

10.1101/2024.07.21.604472 — ecology — Posted on 2024-07-23

1523 The transcriptional landscape of the developing chick trigeminal ganglion

Leonard, C. E.; McIntosh, A.; Taneyhill, L.

10.1101/2024.07.20.604400 — developmental biology — Posted on 2024-07-23

1524 Single-cell transcriptomic profiling of the whole colony of Botrylloides diegensis: Insights into tissue specialization and blastogenesis

Temiz, B.; Meier, M.; Wilson, M. J.

10.1101/2024.07.21.604516 — developmental biology — Posted on 2024-07-23

1525 Inseparable/IER3IP1 are essential for cytokinesis in Drosophila neuroblast and human cells

Kakade, A. A.; Gupta, S.; Varghese, R.; Adicherla, H.; Nagarkar-Jaiswal, S.

10.1101/2024.07.20.604396 — cell biology — Posted on 2024-07-23

1526 Controlled pH Alteration Enables Guanine Accumulation and Drives Crystallization within Iridosomes

Eyal, Z.; Ggorelick-Ashkenazi, A.; Deis, R.; Barzilay, Y.; Broder, Y.; Kellum, A. P.; Varsano, N.; Hartstein, M.; Sorrentino, A.; Kaplan-Ashiri, I.; Rechav, K.; Metzler, R.; Houben, L.; Kronik, L.; Rez, P.; Gur, D.

10.1101/2024.07.20.604036 — cell biology — Posted on 2024-07-23

1527 A novel method (RIM-Deep) enhances imaging depth and resolution stability of deep-cleared brain tissue in inverted confocal microscopy

Liu, Y.; Wang, P.; Zou, J.; Zhou, H.

10.1101/2024.07.19.604108 — neuroscience — Posted on 2024-07-23

1528 Dopaminergic amacrine cells express HCN channels in the developing and adult mouse retina

Romano, E. J.; Zhang, D.-Q.

10.1101/2024.07.20.604440 — neuroscience — Posted on 2024-07-23

1529 A high-performance genetically encoded sensor for cellular imaging of PKC activity in vivo

Yahiro, T.; Bayless-Edwards, L.; Jones, J. A.; Ma, L.; Qin, M.; Mao, T.; Zhong, H.

10.1101/2024.07.19.604387 — neuroscience — Posted on 2024-07-23

1530 predicTTE: An accessible and optimal tool for time-to-event prediction in neurological diseases

Weinreich, M.; McDonough, H.; Yacovzada, N.; Magen, I.; Cohen, Y.; Harvey, C.; Gornall, S.; Boddy, S.; Alix, J.; Mohseni, N.; Kurz, J.; Kenna, K.; Zhang, S.; Iacoangeli, A.; Al-Khleifat, A.; Snyder, M.; Hobson, E.; Al-Chalabi, A.; Hornstein, E.; Elhaik, E.; Shaw, P.; McDermott, C.; Cooper-Knock, J.

10.1101/2024.07.20.604416 — neuroscience — Posted on 2024-07-23

1531 Conscious and Unconscious Emotional Processing: Insights from Behavioral and Pupillary Responses

Taghavi, H.; Sharbaf, L.; Ismailzad, F.; Vahabie, A.-H.; Hatami, J.; Rezayat, E.

10.1101/2024.07.20.604402 — neuroscience — Posted on 2024-07-23

1532 Modulation Of SUDEP By Central Serotonergic Cooperating with Noradrenergic Circuits: A Synergistic-Dependent Manner

Xu, Q.; Xu, X.; Wu, Y.; Yang, Y.; Gu, L.; Zhang, Z.; Zhang, Z.; Di, X.; Wang, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, H.

10.1101/2024.07.20.604434 — neuroscience — Posted on 2024-07-23

1533 Perception of audio-visual synchrony is modulated by walking speed and step cycle phase

Clouston, G.; Davidson, M. J.; Alais, D.

10.1101/2024.07.21.604456 — neuroscience — Posted on 2024-07-23

1534 Context-driven interaction retrieval and classification for modeling, curation, and reuse

Luo, H.; Hansen, C.; Telmer, C. A.; Tang, D.; Arazkhani, N.; Zhou, G.; Spirtes, P.; Miskov-Zivanov, N.

10.1101/2024.07.21.604448 — systems biology — Posted on 2024-07-23

1535 Deletion of wheat alpha-gliadins from chromosome 6D improves gluten strength and reduces immunodominant celiac disease epitopes

Rottersman, M. G.; Zhang, W.; Zhang, J.; Grigorian, G.; Burguener, G.; Carter, C.; Vang, T.; Hegarty, J.; Zhang, X.; Dubcovsky, J.

10.1101/2024.07.19.604379 — plant biology — Posted on 2024-07-23

1536 A Ketogenic Diet Sensitizes Pancreatic Cancer to Inhibition of Glutamine Metabolism

Hajihassani, O.; Zarei, M.; Roichman, A.; Loftus, A.; Boutros, C.; Hue, J. J.; Naji, P.; Boyer, J. A.; Tahhan, S.; Gallagher, P.; Beegan, W.; Choi, J.; Lei, S.; Kim, C.; Rathore, M.; Nakazzi, F.; Shah, I.; Lebo, K.; Cheng, H.; Mudigonda, A.; Alibeckoff, S.; Ji, K.; Graor, H. J.; Miyagi, M.; Vaziri-Gohar, A.; Brunengraber, H.; Wang, R.; Lund, P.; Rothermel, L. D.; Rabinowitz, J. D.; Winter, J. M.

10.1101/2024.07.19.604377 — cancer biology — Posted on 2024-07-23

1537 SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma

Lan, F.; Miao, B.; Ge, L.; He, C.; Wang, X.; Li, X.; Wu, J.; Chen, K.; Wan, J.; Xing, S.; Ren, L.; Shi, Z.; Flores, N. M.; Cheng, J.; Mao, Y.; Xu, X.; Wang, R.; Liang, Z.; Mazur, P.; Cai, J.

10.1101/2024.07.21.604450 — cancer biology — Posted on 2024-07-23

1538 Deep Learning-based Modeling for Preclinical Drug Safety Assessment

Jaume, G.; de Brot, S.; Song, A. H.; Williamson, D. F. K.; Oldenburg, L.; Zhang, A.; Chen, R. J.; Asin, J.; Blatter, S.; Dettwiler, M.; Gopfert, C.; Grau Roma, L.; Soto, S.; Keller, S.; Rottenberg, S.; del-Pozo, J.; Pettit, R.; Le, L. P.; Mahmood, F.

10.1101/2024.07.20.604430 — bioinformatics — Posted on 2024-07-23

1539 Harnessing Dye-induced Photothermal Confinement in Lipid Membranes: A Path to NIR-modulated Artificial Synaptic Vesicles

Sarker, S. R.; Yamazaki, T.; Sou, K.; Takemura, I.; Kurita, Y.; Nomura, K.; Ichimura, M.; Suzuki, T.; Kai, A.; Araki, T.; Hattori, S.; Furuyama, T.; Chang, Y.-T.; Kiya, T.; Arai, S.

10.1101/2024.07.20.604262 — bioengineering — Posted on 2024-07-23

1540 Complete enzymatic depolymerization of polyethylene terephthalate (PET) plastic using a Saccharomyces cerevisiae-based whole-cell biocatalyst

Gulati, S.; Sun, Q.

10.1101/2024.07.20.604433 — bioengineering — Posted on 2024-07-23

1541 Proteome-wide neuropeptide identification using NeuroPeptide-HMMer (NP-HMMer)

Zandawala, M.; Amir, M. B.; Shin, J.; Yim, W. C.; Yanez-Guerra, L. A.

10.1101/2024.07.20.604414 — evolutionary biology — Posted on 2024-07-23

1542 Mitochondria affect photosynthesis through altered tissue levels of oxygen

Punkkinen, M.; Blokhina, O.; Peralta Ogorek, L. L.; Kim, M.; Fagerstedt, K. V.; Vierling, E.; Pedersen, O.; Shapiguzov, A.

10.1101/2024.07.19.604342 — plant biology — Posted on 2024-07-23

1543 The LYCOPENE EPSILON CYCLASE untranslated mRNA leader modulates carotenoid feedback and post-transcriptional regulation

Alagoz, Y.; Nayak, J.; Aryal, R.; Watkins, J.; Holland, S.; Tissue, D.; Pogson, B. J.; Cazzonelli, C. I.

10.1101/2024.07.19.604344 — plant biology — Posted on 2024-07-23

1544 TRAIL-induced cytokine production via NFKB2 pathway promotes neutrophil chemotaxis and immune suppression in triple negative breast cancers

Kundu, M.; Greer, Y. E.; Lobanov, A.; Ridnour, L.; Donahue, R. N.; Ng, Y.; Ratnayake, S.; Voeller, D.; Weltz, S.; Chen, Q.; Lockett, S. J.; Cam, M.; Meerzaman, D.; Wink, D. A.; Lipkowitz, S.

10.1101/2024.07.19.604341 — cancer biology — Posted on 2024-07-23

1545 Hair cells in the cochlea must tune resonant modes to the edge of instability without destabilizing collective modes

Momi, A. S.; Abbott, M. C.; Rubinfien, J.; Machta, B. B.; Graf, I. R.

10.1101/2024.07.19.604330 — biophysics — Posted on 2024-07-23

1546 Tiberius: End-to-End Deep Learning with an HMM for Gene Prediction

Gabriel, L.; Becker, F.; Hoff, K. J.; Stanke, M.

10.1101/2024.07.21.604459 — bioinformatics — Posted on 2024-07-23

1547 A deep learning-based multiscale integration of spatial omics with tumor morphology.

Schmauch, B.; Herpin, L.; Olivier, A.; Duboudin, T.; Dubois, R.; Gillet, L.; Schiratti, J.-B.; Di Proietto, V.; Le Corre, D.; Bourgoin, A.; Taïeb, J.; Emile, J.-F.; Fridman, W. H.; Pronier, E.; Laurent-Puig, P.; Durand, E. Y.

10.1101/2024.07.22.604083 — bioinformatics — Posted on 2024-07-23

1548 FEHAT: Efficient, Large scale and Automated Heartbeat Detection in Medaka Fish Embryos.

Ferreira, M.; Stricker, S.; Fitzgerald, T. W.; Monahan, J.; Defranoux, F.; Watson, P.; Welz, B.; Hammouda, O.; Wittbrodt, J.; Birney, E.

10.1101/2024.07.21.604466 — bioinformatics — Posted on 2024-07-23

1549 3D printed bioelectronic scaffolds with soft tissue-like stiffness

Okafor, S. S.; Park, J.; Liu, T.; Goestenkors, A. P.; Alvarez, R. M.; Semar, B. A.; Yu, J. S.; O'Hare, C. P.; Montgomery, S. K.; Friedman, L. C.; Rutz, A. L.

10.1101/2024.07.19.604334 — bioengineering — Posted on 2024-07-23

1550 Variation in the fitness impact of translationally optimal codons among animals

Benitiere, F.; Lefebure, T.; Duret, L.

10.1101/2024.07.22.604600 — genomics — Posted on 2024-07-23

1551 In-utero rescue of neurological dysfunction in a mouse model of Wiedemann-Steiner syndrome

Reynisdottir, T.; Anderson, K. J.; Brinn, A.; Franklin, K.; Ouyang, J.; Snorradottir, A. O.; Lutz, C. M.; Zuberi, A. R.; DeLeon, V. B.; Bjornsson, H. T.

10.1101/2024.07.19.604339 — genetics — Posted on 2024-07-23

1552 Interactions between weather, ungulates and geese create opportunities for wood-pasture cycles

Kramer, K.; Cornelissen, P.; Groot Bruinderink, G. W. T. A.; Kuiters, L.; Lammertsma, D.; Vulink, J. T.; Van Wieren, S. E.; Prins, H. H. T.

10.1101/2024.07.19.604241 — ecology — Posted on 2024-07-23

1553 Effects of Bacillus thuringiensis subsp. kurstaki application on non-target nocturnal macromoth biodiversity in the eastern boreal forest, Canada.

Young, J. O.; Bowden, J. J.; Moise, E. R. D.; Scott, R.; Schmidt, C. B.

10.1101/2024.07.19.604320 — ecology — Posted on 2024-07-23

1554 Axis reset is rate limiting for onset of whole-body regenerative abilities during planarian development

Booth, C. L. T.; Stevens, B. C.; Stubbert, C. A.; Kallgren, N. T.; Davies, E. L.

10.1101/2024.07.19.604337 — developmental biology — Posted on 2024-07-23

1555 A Novel Whole Tissue Explant Model of Hidradenitis Suppurativa

Leboit, P. E.; Patel, D. U.; Cohen, J. N.; Moss, M. I.; Naik, H. B.; Yates, A. E.; Harris, H. W.; Klufas, D. M.; Kim, E. A.; Neuhaus, I. M.; Hansen, S. L.; Kyle, R. L.; Kelly, M.; Rosenblum, M. D.; Lowe, M. M.

10.1101/2024.07.19.603617 — immunology — Posted on 2024-07-23

1556 Neuro-immunology in a mouse model of anti-NMDAR encephalitis and assessment of treatment approaches

Maudes, E.; Planaguma, J.; Marmolejo, L.; Radosevic, M.; Serafim, A. B.; Aguilar, E.; Sindreu, C.; Landa, J.; Garcia-Serra, A.; Mannara, F.; Cunquero, M.; Smith, A.; Milano, C.; Peixoto-Moledo, P.; Guasp, M.; Ruiz-Garcia, R.; Gray, S. M.; Spatola, M.; Loza-Alvarez, P.; Sabater, L.; Matute, C.; Dalmau, J.

10.1101/2024.07.19.604240 — neuroscience — Posted on 2024-07-23

1557 Long-lived adult-born hippocampal neurons promote successful cognitive aging

Blin, N.; Charrier, V.; Farrugia, F.; Cartier, E.; Pacary, E.; Koehl, M.; Lois, C.; Lie, D. C.; Masachs, N.; Abrous, N.

10.1101/2024.07.19.604332 — neuroscience — Posted on 2024-07-23

1558 Robust and Memoryless Median Estimation for Real-Time Spike Detection

Burman, A.; Sole-Casals, J.; Lew, S. E.

10.1101/2024.07.19.604279 — neuroscience — Posted on 2024-07-23

1559 Return of intracranial beta oscillations and traveling waves with recovery from traumatic brain injury

Vaz, A. P.; Wathen, C.; Miranda, S.; Thomas, R.; Darlington, T.; Jabarkheel, R.; Tomlinson, S.; Arena, J.; Bond, K.; Salwi, S.; Ajmera, S.; Bachschmid-Romano, L.; Gugger, J.; Sandsmark, D.; Diaz-Arrastia, R.; Schuster, J.; Ramayya, A.; Cajigas, I.; Pesaran, B.; Chen, I.; Petrov, D.

10.1101/2024.07.19.604293 — neuroscience — Posted on 2024-07-23

1560 A distinct down state assembly in retrosplenial cortex during slow-wave sleep

Opalka, A. N.; Dougherty, K. J.; Wang, D. V.

10.1101/2024.07.19.604325 — neuroscience — Posted on 2024-07-23

1561 Metabolomic differentiation of amino acid profiles in adult deltamethrin-resistant Aedes albopictus (L.)

Ong, S.-Q.; Nair, G.; Ishak, I. H.; Paulous, R.

10.1101/2024.07.19.604257 — zoology — Posted on 2024-07-23

1562 Systemic inflammation is a minor contributor to remnant cholesterol atherogenicity

Kraaijenhof, J. M.; Kerkvliet, M.; Nurmohamed, N. S.; Grefhorst, A.; Kroon, J.; Wareham, N. J.; Hovingh, G. K.; Stroes, E. S.; Boekholdt, S. M.; Reeskamp, L. F.

10.1101/2024.07.18.604203 — systems biology — Posted on 2024-07-23

1563 Hysteresis and noise floor in gene expression optimised for persistence against lethal events

Bokes, P.; Singh, A.

10.1101/2024.07.19.604229 — systems biology — Posted on 2024-07-23

1564 Arabidopsis root apical meristem adaptation to an osmotic gradient condition: an integrated approach from cell expansion to gene expression

Piriz-Pezzutto, S.; Martinez-More, M.; Sainz, M. M.; Borsani, O.; Sotelo, M.

10.1101/2024.07.19.604290 — plant biology — Posted on 2024-07-23

1565 Iron-induced Transcriptional and Microbiome Changes in Host Roots Associated with Drought Tolerance in Sorghum

Kabir, A. H.; Brailey-Jones, P.; Abdelrahman, M.; Tran, L.-S. P.; Bennetzen, J. L.

10.1101/2024.07.19.604343 — plant biology — Posted on 2024-07-23

1566 Role of Kir4.1/Kir5.1 in mediating Angiotensin-II (Ang-II)-induced stimulation of thiazide-sensitive Na-Cl cotransporter.

Wang, W.-H.; Duan, X.-P.; Meng, X.-X.; Xiao, Y.; Zhang, C.; Gu, R.; Lin, D.-H.

10.1101/2024.07.19.604336 — physiology — Posted on 2024-07-23

1567 Downregulation of acetyl-CoA carboxylase suppresses the malignant progression of oral cancer

jia, g.

10.1101/2024.07.21.604509 — cancer biology — Posted on 2024-07-23

1568 European Robin Cryptochrome-4a Associates with Lipid Bilayers in an Ordered Manner, Fulfilling a Molecular-Level Condition for Magnetoreception

Majewska, M.; Hanic, M.; Bartoelke, R.; Schmidt, J.; Mouritsen, H.; Koch, K.-W.; Solov'yov, I. A.; Brand, I.

10.1101/2024.07.20.604329 — biophysics — Posted on 2024-07-23

1569 Extending the Acute Skin Response Spectrum to Include the Far-UVC

Gutierrez-Bayona, N. E.; Petersen, C.; Hashmi, R. H.; Buonanno, M.; Shuryak, I.; Ponnaiya, B.; Kleiman, N. J.; Brenner, D. J.; Welch, D.

10.1101/2024.07.19.604306 — biophysics — Posted on 2024-07-23

1570 Empowering Integrative and Collaborative Exploration of Single-Cell and Spatial Multimodal Data with SGS

Xia, T.; Sun, J.; Lu, F.; Luo, Y.; Mao, Y.; Xu, L.; Wang, Y.

10.1101/2024.07.19.604227 — bioinformatics — Posted on 2024-07-23

1571 PepCleav: a classification method for evaluating the cleavability of peptide fragments presented by MHC class I

Jiang, D.; Zhu, W.; Tan, W.; Du, H.

10.1101/2024.07.19.604254 — bioinformatics — Posted on 2024-07-23

1572 Bone mineral density affects tumor growth by shaping microenvironmental heterogeneity

Whitman, M. A.; Mantri, M.; Spanos, E.; Estroff, L. A.; De Vlaminck, I.; Fischbach, C.

10.1101/2024.07.19.604333 — bioengineering — Posted on 2024-07-23

1573 High-yield production of recombinant human myelin oligodendrocyte glycoprotein in SHuffle bacteria without a refolding step

Wu, W.; Gupta, S.; Sagan, S. A.; Moseley, C. E.; Zamvil, S. S.; Pak, J. E.

10.1101/2024.07.22.602974 — biochemistry — Posted on 2024-07-23

1574 Dads on duty: First account of nest sitting in barnacle ganders

Scheiber, I. B. R.; Slettenhaar, A. J.; Loonen, M. J. J. E.; de Jong, M. E.

10.1101/2024.07.19.604238 — animal behavior and cognition — Posted on 2024-07-23

1575 Genetic characterization of the complete genome of a strain of Chikungunya virus circulating in Brazil: a strategy for the surveillance and control of Arboviral diseases with epidemic potential in Latin America.

Villarreal Julio, R. G.; Sepulveda Ayala, J. D.; Pabon Mir, D. A.; Zapata Arango, J. F.; Palacio Estrada, M.; Patino Mejia, A. F.; Zea Restrepo, S.

10.1101/2024.07.21.602720 — genomics — Posted on 2024-07-23

1576 Reviving the Desired Gains Index: An optimal solution for parent selection in public plant breeding programs

Werner, C. R.; Gardner, K. A.; Tolhurst, D. J.

10.1101/2024.07.21.603926 — genetics — Posted on 2024-07-23

1577 Advances in Estimating Level-1 Phylogenetic Networks from Unrooted SNPs

Warnow, T.; Tabatabaee, Y.; Evans, S. N.

10.1101/2024.07.19.604386 — evolutionary biology — Posted on 2024-07-23

1578 Test of a conservation intervention highlights temporal variability in hybridization dynamics in Catostomus fishes

Campbell, J. N.; Mandeville, E.; Hooley-Underwood, Z.

10.1101/2024.07.19.604301 — evolutionary biology — Posted on 2024-07-23

1579 Transform the Information Landscape: Applying Waddington Landscape to Information Theory of Aging and Epigenetic Rejeuvanation

Wu, Y.

10.1101/2024.07.20.604423 — developmental biology — Posted on 2024-07-23

1580 Design principles of small intestinal crypt maintenance

banjac, I.; Maimets, M.; Tsang, I.; Dioli, M.; Hansen, S.; Krizic, K.; Bressan, R.; Lovkvist, C.; Jensen, K.

10.1101/2024.07.19.604296 — cell biology — Posted on 2024-07-23

1581 MegaMASLD: An interactive platform for exploring stratified transcriptomic signatures in MASLD progression

Cheng, H. S.; Chua, D.; Chan, S. T.; Yew, K. C.; Wong, H. S.; Tan, N. S.

10.1101/2024.07.21.603199 — molecular biology — Posted on 2024-07-23

1582 Diversity and functional specialization of oyster immune cells uncovered by integrative single cell level investigations

De La Forest Divonne, S.; Pouzadoux, J.; Romatif, O.; Montagnani, C.; Mitta, G.; Destoumieux-Garzon, D.; Gourbal, B.; Charriere, G. M.; Vignal, E.

10.1101/2024.07.19.604245 — immunology — Posted on 2024-07-23

1583 PLAbDab-nano: a database of camelid and shark nanobodies from patents and literature

Gordon, G. L.; Greenshields-Watson, A. L.; Agarwal, P.; Wong, A.; Boyles, F.; Hummer, A.; Lujan Hernandez, A. G.; Deane, C. M.

10.1101/2024.07.19.604232 — immunology — Posted on 2024-07-23

1584 Cryopreservation Enables Long-Term Studies of Octopus vulgaris Hemocyte Immune Functions

Costa, M. M.; Paredes, E.; Peleteiro, M.; Gambon, F.; Dios, S.; Gestal, C.

10.1101/2024.07.19.604316 — immunology — Posted on 2024-07-23

1585 Structural diversity of mitochondria in the neuromuscular system across development

Bae, J. A.; Choi, M.-k.; Ahn, S.; Ko, G.; Choe, D. T.; Yim, H.; Nguyen, K. C. Q.; Hall, D. H.; Kim, J. S.; Lee, J.

10.1101/2024.07.19.604219 — neuroscience — Posted on 2024-07-23

1586 Adaptive Safety Coding in the Prefrontal Cortex

Tashjian, S. M.; Cussen, J.; Deng, W.; Zhang, B.; Mobbs, D.

10.1101/2024.07.19.604228 — neuroscience — Posted on 2024-07-23

1587 Olfactory cortical outputs recruit and shape distinct brain-wide spatiotemporal networks

Ma, T.; Wang, X.; Lin, X.; Wen, J.; Xie, L.; Cao, P.; Leong, A. T. L.; Wu, E. X.

10.1101/2024.07.19.604242 — neuroscience — Posted on 2024-07-23

1588 Novel verbal instructions recruit abstract neural patterns of time-variable information dimensionality

Pena, P.; Palenciano, A. F.; Gonzalez-Garcia, C.; Ruz, M.

10.1101/2024.07.19.603493 — neuroscience — Posted on 2024-07-23

1589 Power-law adaptation in the presynaptic vesicle cycle

Mikulasch, F. A.; Georgiev, S. V.; Rudelt, L.; Rizzoli, S.; Priesemann, V.

10.1101/2024.07.19.604253 — neuroscience — Posted on 2024-07-23

1590 Spiking neural network models of sound localisation via a massively collaborative process

Ghosh, M.; Habashy, K. G.; De Santis, F.; Fiers, T.; Ercelik, D. F.; Meszaros, B.; Friedenberger, Z.; Bena, G.; Hong, M.; Abubacar, U.; Byrne, R. T.; Riquelme, J. L.; Liu, Y. H.; Aizenbud, I.; Bicknell, B. A.; Bormuth, V.; Antonietti, A.; Goodman, D. F. M.

10.1101/2024.07.19.604252 — neuroscience — Posted on 2024-07-23

1591 Uncovering the Neural Correlates of the Urge-to-Blink: A Study Utilising Subjective Urge Ratings and Paradigm Free Mapping

Houlgreave, M. S.; Urunuela, E.; Caballero-Gaudes, C.; Gowland, P. A.; Dyke, K.; Brandt, V.; Mohammed, I.; Sanchez Panchuelo, R. M.; Jackson, S. R.

10.1101/2024.07.19.603913 — neuroscience — Posted on 2024-07-23

1592 A Burst-Dependent Algorithm for Neuromorphic On-Chip Learning of Spiking Neural Networks

Stuck, M.; Naud, R.

10.1101/2024.07.19.604308 — neuroscience — Posted on 2024-07-23

1593 Instantaneous Flow Analysis of Contractile Cytoskeletal Structures Affected by the Dysregulation of Kinesin and Tropomyosin Motors

Matov, A.

10.1101/2024.06.28.601275 — cell biology — Posted on 2024-07-23

1594 Integration of multi-omics and deep phenotyping provides novel insights into multiple abiotic stress responses in potato

Zagorscak, M.; Abdelhakim, L.; Rodriguez-Granados, N. Y.; Siroka, J.; Ghatak, A.; Bleker, C.; Blejec, A.; Zrimec, J.; Novak, O.; Pencik, A.; Baebler, S.; Borroto, L. P.; Schuy, C.; Zupanic, A.; Afjehi-Sadat, L.; Wurzinger, B.; Weckwerth, W.; Pompe-Novak, M.; Knight, M. R.; Strnad, M.; Bachem, C. W.; Chaturvedi, P.; Sonnewald, S.; Sasidharan, R.; Panzarova, K.; Gruden, K.; Teige, M.

10.1101/2024.07.18.604140 — plant biology — Posted on 2024-07-23

1595 Polysaccharide breakdown products drive degradation-dispersal cycles of foraging bacteria through changes in metabolism and motility

Stubbusch, A. K. M.; Keegstra, J. M.; Schwartzman, J.; Pontrelli, S.; Clerc, E. E.; Charlton, S.; Stocker, R.; Magnabosco, C.; Schubert, O. T.; Ackermann, M.; D'Souza, G. G.

10.1101/2023.07.14.548877 — microbiology — Posted on 2024-07-23

1596 Unaware Processing of Words Activates Experience-Derived Information in Conceptual-Semantic Brain Networks

Ghio, M.; Cassone, B.; Tettamanti, M.

10.1101/2024.07.15.603501 — neuroscience — Posted on 2024-07-23

1597 STOP1 dominates Arabidopsis tolerance to ammonium over NRT1.1/NPF6.3/CHL1

Hachiya, T.; Sakai, M.; Nakagawa, T.; Sakakibara, H.

10.1101/2024.05.06.592859 — plant biology — Posted on 2024-07-23

1598 The effect of Vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function.

Seaward Brain, H. P.; Georgiou, C.; Mason, H. D.; Rice, S.

10.1101/2023.06.16.545289 — physiology — Posted on 2024-07-23

1599 Methionine Restriction Reduces Lung Cancer Progression and Increases Chemotherapy Response

Naughton, K. J.; Song, X.; Childress, A. R.; Skaggs, E. M.; Byrd, A. L.; Gosser, C. M.; Esoe, D.-P.; DuCote, T. J.; Plaugher, D. R.; Lukyanchuk, A.; Goettl, R. A.; Liug, J.; Brainson, C. F.

10.1101/2024.06.25.599795 — cancer biology — Posted on 2024-07-23

1600 Genome-wide CRISPR screen identifies KEAP1 perturbation as a vulnerability of ARID1A-deficient cells

Fournier, L.-A.; Kalantari, F.; Wells, J. P.; Lee, J. S.; Trigo-Gonzalez, G.; Moksa, M. M.; Smith, T.; White, J.; Shanks, A.; Wang, L.; Su, E.; Wang, Y.; Huntsman, D. G.; Hirst, M.; Stirling, P. C.

10.1101/2023.11.14.566591 — cancer biology — Posted on 2024-07-23

1601 Dynamic basis of lipopolysaccharide export by LptB2FGC

Dajka, M.; Rath, T.; Morgner, N.; Joseph, B.

10.1101/2024.05.20.594984 — biophysics — Posted on 2024-07-23

1602 STEP: Spatial Transcriptomics Embedding Procedure for Multi-scale Biological Heterogeneities Revelation in Multiple Samples

Li, L.; Li, Z.; Yin, X.-m.; Xu, X.

10.1101/2024.04.15.589470 — bioinformatics — Posted on 2024-07-23

1603 Functionally constrained human proteins are less prone to disruption of stability caused by single amino acid substitutions

Andrews, D.; Lehmann, N.; May, M.; Goodall, L.; Cho, E.; Chuah, A.

10.1101/2024.07.14.603410 — genomics — Posted on 2024-07-23

1604 Modifiable clinical dental impression methods to obtain whole-mouth and detailed dental traits from non-livestock vertebrates

Wibisana, J. N.; Sallan, R.; Ota, T.; Puchenkov, P.; Kubo, T.; Sallan, L.

10.1101/2023.11.21.567763 — evolutionary biology — Posted on 2024-07-23

1605 Longitudinal sequencing reveals polygenic andepistatic nature of genomic response to selection

Forsberg, S. K. G.; Melo, D.; Grenier, J.; Wolf, S.; Tang, M.; Henry, L.; Pallares, L. F.; Clark, A. G.; Ayroles, J. F.

10.1101/2024.07.22.604612 — evolutionary biology — Posted on 2024-07-23

1606 Insect metamorphosis is regulated differently between sexes by members of a microRNA cluster

Li, C.; Chan, K. K.; Nong, W.; Chen, S.; So, W. L.; Qu, Z.; Wu, H. W. C.; Yip, H. Y.; Chan, C. B.; Tobe, S. S.; Bendena, W.; Kai, Z. P.; Hui, J. H. l.

10.1101/2024.06.25.600558 — evolutionary biology — Posted on 2024-07-23

1607 Bacillus toyonensis biovar Thuringiensis: an overlooked entomopathogen?

Sauka, D. H.; Del Valle, E. E.; Palma, L.

10.1101/2024.07.21.604280 — evolutionary biology — Posted on 2024-07-23

1608 Spectral algal fingerprinting and long sequencing in synthetic algal-microbial communities

Meirkhanova, A.; Marks, S.; Feja, N.; Vorobjev, I. A.; Barteneva, N. S.

10.1101/2024.07.08.602014 — ecology — Posted on 2024-07-23

1609 Contribution of the neuron-specific ATP1A3 to embryonic spinal circuit emergence

Dinvaut, S.; Calvet, S.; Comte, J.-C.; Gury, R.; Pascual, O.; Andre, M.; Ferrigno, R.; Honnorat, J.; Moret, F.; Marcy, G.; Falk, J.; Castellani, V.

10.1101/2024.06.11.598491 — developmental biology — Posted on 2024-07-23

1610 Rapalink-1 reveals novel mTOR-dependent genes and the role of agmatinases in cellular growth and chronological lifespan

Kumar, J.; Rallis, C.

10.1101/2024.07.20.604404 — cell biology — Posted on 2024-07-23

1611 mTOR activation induces endolysosomal remodeling and nonclassical secretion of IL-32 via exosomes in inflammatory reactive astrocytes

Leng, K.; Rooney, B.; McCarthy, F.; Xia, W.; Rose, I. V. L.; Bax, S.; Chin, M. Y.; Fathi, S.; Herrington, K. A.; Leonetti, M.; Kao, A. W.; Fancy, S. P. J.; Elias, J. E.; Kampmann, M.

10.1101/2021.09.11.459904 — cell biology — Posted on 2024-07-23

1612 Bilateral regulation of EGFR activity and local PI dynamics observed with superresolution microscopy

Abe, M.; Yanagawa, M.; Hiroshima, M.; Kobayashi, T.; Sako, Y.

10.1101/2024.02.01.578337 — cell biology — Posted on 2024-07-23

1613 Multiomics unveils extracellular vesicle-driven mechanisms of endothelial communication in human carotid atherosclerosis

Raju, S.; Turner, M. E.; Cao, C.; Abdul-Samad, M.; Punwasi, N.; Blaser, M. C.; Cahalane, R. M.; Botts, S. R. C.; Prajapati, K.; Patel, S.; Wu, R.; Gustafson, D.; Galant, N. J.; Fiddes, L.; Chemaly, M.; Hedin, U.; Matic, L.; Seidman, M.; Subasri, V.; Singh, S. A.; Aikawa, E.; Fish, J. E.; Howe, K. L.

10.1101/2024.06.21.599781 — cell biology — Posted on 2024-07-23

1614 The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice.

Sakai, H.; Uno, H.; Yamakawa, H.; Tanaka, K.; Ikedo, A.; Uezumi, A.; Ohkawa, Y.; Imai, Y.

10.1101/2023.11.21.568190 — molecular biology — Posted on 2024-07-23

1615 Development and evaluation of statistical and Artificial Intelligence approaches with microbial shotgun metagenomics data as an untargeted screening tool for use in food production

Beck, K. L.; Haiminen, N.; Agarwal, A.; Carrieri, A.-P.; Madgwick, M.; Kelly, J.; Pylro, V.; Kawas, B.; Wiedmann, M.; Ganda, E.

10.1101/2022.08.16.504221 — microbiology — Posted on 2024-07-23

1616 Mobile Integrons Encode Phage Defence Systems

Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ortiz-Miravalles, L.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.

10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-23

1617 A generic noninvasive neuromotor interface for human-computer interaction

Ctrl-labs at Reality Labs, ; Sussillo, D.; Kaifosh, P.; Reardon, T.

10.1101/2024.02.23.581779 — neuroscience — Posted on 2024-07-23

1618 Multiple Postsynaptic Protein Levels in Adult Superior Colliculus Are Unaffected by Dark Rearing from Birth

Juvale, P.; Mudd, D. B.; Shree, N.; Pallas, S. L.

10.1101/2022.10.06.511220 — neuroscience — Posted on 2024-07-23

1619 Ternary representation of contextual information along the CA1 transverse axis

Duan, Y.-L.; Hu, S.-Y.; Ge, X.-F.; Long, J.-L.; Deng, C.; Sun, Y.-M.; Li, C.-J.; Zhang, R.; Cai, X.; Lu, L.

10.1101/2024.06.06.597717 — neuroscience — Posted on 2024-07-23

1620 Anatomical and behavioral correlates of auditory perception in developmental dyslexia

Qi, T.; Mandelli, M. L.; Watson Pereira, C. L.; Wellman, E.; Bogley, R.; Licata, A. E.; Chang, E. F.; Oganian, Y.; Gorno-Tempini, M. L.

10.1101/2023.05.09.539936 — neuroscience — Posted on 2024-07-23

1621 Working Memory Gating in Obesity is Moderated by Striatal Dopaminergic Gene Variants

Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.

10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-07-23

1622 Enhancing sleep via rocking ameliorates motor behavior and reduces beta-amyloid levels in a mouse model of Alzheimer's disease

Zhang, L.; Santoni, L.; Ngo, N. A.; Simayi, R.; Ficiara, E.; de Vivo, L.; Bellesi, M.

10.1101/2024.07.15.603512 — neuroscience — Posted on 2024-07-23

1623 Trends in Self-citation Rates in High-impact Neurology, Neuroscience, and Psychiatry Journals

Rosenblatt, M.; Mehta, S.; Peterson, H.; Dadashkarimi, J.; Rodriguez, R. X.; Foster, M. L.; Adkinson, B. D.; Liang, Q.; Kimble, V. M.; Ye, J.; McCusker, M. C.; Farruggia, M. C.; Rolison, M.; Westwater, M. L.; Jiang, R.; Noble, S.; Scheinost, D.

10.1101/2022.09.27.509533 — neuroscience — Posted on 2024-07-23

1624 A thalamic hub-and-spoke circuit enables visual perception during action by coordinating visuomotor dynamics

Vega-Zuniga, T.; Sumser, A.; Symonova, O.; Koppensteiner, P.; Schmidt, F. H.; Joesch, M.

10.1101/2023.12.23.573221 — neuroscience — Posted on 2024-07-23

1625 GABA-ergic inhibition in human hMT+ predicts visuo-spatial intelligence mediated through the frontal cortex

Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.

10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-07-23

1626 Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning

Olszynski, K. H.; Polowy, R.; Wardak, A. D.; Laska, I. A.; Grymanowska, A. W.; Pulawski, W.; Gawrys, O.; Kolinski, M.; Filipkowski, R. K.

10.1101/2023.04.06.535936 — neuroscience — Posted on 2024-07-23

1627 In silico identification of switching nodes in metabolic networks

Mairet, F.

10.1101/2023.05.17.541195 — systems biology — Posted on 2024-07-23

1628 With the leisure of time, kinetic proofreading can still perform reliable ligand discrimination

Xiao, F.; Galstyan, V.

10.1101/2024.01.11.575129 — systems biology — Posted on 2024-07-23

1629 Subcellular ToF-SIMS imaging of the snow alga Sanguina nivaloides by combining high mass and high lateral resolution acquisitions

Seydoux, C.; Ezzedine, J. A.; Si Larbi, G.; Ravanel, S.; Marechal, E.; Barnes, J.-P.; Jouneau, P.-H.

10.1101/2024.07.15.603549 — plant biology — Posted on 2024-07-23

1630 The impact of ligand-induced oligomer dissociation on enzyme diffusion, directly observed at the single-molecule level

Yancheva, Y. D.; Kaya, S. G.; Belyy, A.; Fraaije, M. W.; Tych, K.

10.1101/2024.01.28.577687 — biophysics — Posted on 2024-07-23

1631 Image processing tools for petabyte-scale light sheet microscopy data

Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Chong, J. G.; Hong, J. L.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.

10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-07-23

1632 Ribosomal Frameshifting Selectively Modulates the Assembly, Function, and Pharmacological Rescue of a Misfolded CFTR Variant

Carmody, P.; Roushar, F. J.; Tedman, A.; Wang, W.; Herwig, M.; Kim, M.; McDonald, E. F.; Noguera, K.; Wong-Roushar, J.; Poirier, J.-L.; Zelt, N.; Pockrass, B.; McKee, A. G.; Kuntz, C. P.; Raju, S. V.; Plate, L.; Penn, W. D.; Schlebach, J. P.

10.1101/2023.05.02.539166 — biochemistry — Posted on 2024-07-23

1633 Negative selection allows human primary fibroblasts to tolerate high somatic mutation loads induced by N-ethyl-N-nitrosourea

Heid, J.; Cutler, R.; Sun, S.; Lee, M.; Maslov, A. Y.; Dong, X.; Sidoli, S.; Vijg, J.

10.1101/2024.04.07.588286 — genetics — Posted on 2024-07-23

1634 Prevalent fast evolution of genes involved in heterochromatin functions

Lin, L.; Huang, Y.; McIntyre, J.; Chang, C.-H.; Colmenares, S. S.; Lee, G. Y. C.

10.1101/2024.03.03.583199 — evolutionary biology — Posted on 2024-07-23

1635 Periosteal skeletal stem cells can migrate into the bone marrow and support hematopoiesis after injury

Marchand, T.; Akinnola, K. E.; Takeishi, S.; Maryanovich, M.; Pinho, S.; Saint-Vanne, J.; Birbrair, A.; Lamy, T.; Tarte, K.; Frenette, P.; Gritsman, K.

10.1101/2023.01.12.523842 — cell biology — Posted on 2024-07-23

1636 Spatial propagation of temperate phages within and among biofilms

Winans, J.; Garcia, S.; Zeng, L.; Nadell, C.

10.1101/2023.12.20.571119 — microbiology — Posted on 2024-07-23

1637 Non-Negative Connectivity Causes Bow-Tie Architecture in Neural Circuits

Liu, Z.; Du, C.; Wong-Lin, K.; Wang, D.-H.

10.1101/2024.07.19.604347 — neuroscience — Posted on 2024-07-23

1638 A Simple Strategy for Identifying Conserved Features across Non-independent Omics Studies

Reed, E.; Sebastiani, P.

10.1101/2023.11.22.568276 — bioinformatics — Posted on 2024-07-23

1639 From Noise to Knowledge: Diffusion Probabilistic Model-Based Neural Inference of Gene Regulatory Networks

Zhu, H.; Slonim, D. K.

10.1101/2023.11.05.565675 — bioinformatics — Posted on 2024-07-23

1640 Unveiling Assembly Errors in Immunoglobulin Loci: A Comprehensive Evaluation of Long-read Genome Assemblies Across Vertebrates

Zhu, Y.; Watson, C. T.; Safonova, Y.; Pennell, M.; Bankevich, A.

10.1101/2024.07.19.604360 — genomics — Posted on 2024-07-23

1641 Scorpio : Enhancing Embeddings to Improve Downstream Analysis of DNA sequences

Refahi, M.; Sokhansanj, B. A.; Mell, J. C.; Brown, J.; Yoo, H.; Hearne, G.; Rosen, G.

10.1101/2024.07.19.604359 — genomics — Posted on 2024-07-23

1642 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems

Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Mckeown, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M.

10.1101/2024.02.19.579948 — genomics — Posted on 2024-07-23

1643 Absence of Evidence is Not Evidence of Absence: The many flaws in the case against transgenerational epigenetic inheritance of pathogen avoidance in C. elegans

Kaletsky, R.; Moore, R. S.; Sengupta, T.; Soto, R.; Ceballos-Llera, B.; Murphy, C.

10.1101/2024.06.07.597568 — genetics — Posted on 2024-07-23

1644 Modeling biases from low-pass genome sequencing to enable accurate population genetic inferences

Fonseca, E. M.; Tran, L. N.; Mendoza, H.; Gutenkunst, R. N.

10.1101/2024.07.19.604366 — evolutionary biology — Posted on 2024-07-23

1645 Centennial recovery of recent human-disturbed forests

Rodriguez-Una, A.; Cruz-Alonso, V.; Lopez-Lopez, J. A.; Moreno-Mateos, D.

10.1101/2024.07.21.604432 — ecology — Posted on 2024-07-23

1646 High microsatellite but no mitochondrial DNA variation in an invasive Japanese mainland population of the parasitoid wasp Melittobia sosui

Abe, J.; Takahashi, J.-i.; Tsuchida, K.

10.1101/2024.07.19.604378 — ecology — Posted on 2024-07-23

1647 The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation

Abidi, S. N. F.; Chan, S.; Seidel, K.; Lafkas, D.; Vermeulen, L.; Peale, F.; Siebel, C. W.

10.1101/2024.05.05.592588 — developmental biology — Posted on 2024-07-23

1648 MDC1 mediates Pellino recruitment to sites of DNA double-strand breaks

Torres Esteban, M.; Stewart, M. J.; Bragginton, E.; Jeanrenaud, A.; Smerdon, S. J.; Stucki, M.

10.1101/2024.07.20.604390 — cell biology — Posted on 2024-07-23

1649 Molecular architecture of glideosome and nuclear F-actin in Plasmodium falciparum

Prazak, V.; Vasishtan, D.; Grunewald, K.; Douglas, R. G.; Ferreira, J. L.

10.1101/2024.04.22.590301 — microbiology — Posted on 2024-07-23

1650 Antimicrobial Resistance in Diverse Urban Microbiomes: Uncovering Patterns and Predictive Markers

Toscan, R. B.; Subramanian, B.; Stomma, P.; Łabaj, P. P.; Lesinski, W.; Rudnicki, W.

10.1101/2024.03.08.584116 — microbiology — Posted on 2024-07-23

1651 Consequences of decoy site repair and feedback regulation on neurotransmission dynamics

Gambrell, O.; Singh, A.

10.1101/2024.07.20.604401 — neuroscience — Posted on 2024-07-23

1652 Directionality bias underpinsdivergent spatiotemporalprogression of Alzheimer-relatedtauopathy in mouse models

Torok, J.; Mezias, C.; Raj, A.

10.1101/2024.06.04.597478 — neuroscience — Posted on 2024-07-23

1653 Striosomes Target Nigral Dopamine-Containing Neurons via Direct-D1 and Indirect-D2 Pathways Paralleling Classic Direct-Indirect Basal Ganglia Systems

Lazaridis, I.; Crittenden, J. R.; Ahn, G.; Hirokane, K.; Yoshida, T.; Wickersham, I.; Mahar, A.; Skara, V.; Loftus, J. H.; Parvataneni, K.; Meletis, K.; Ting, J. T.; Hueske, E.; Matsushima, A.; Graybiel, A. M.

10.1101/2024.06.01.596922 — neuroscience — Posted on 2024-07-23

1654 Lateral inhibition in V1 controls neural & perceptual contrast sensitivity

Del Rosario, J.; Coletta, S.; Kim, S. H.; Mobille, Z.; Peelman, K.; Williams, B.; Otsuki, A. J.; Del Castillo Valerio, A.; Worden, K.; Blanpain, L. T.; Lovell, L.; Choi, H.; Haider, B.

10.1101/2023.11.10.566605 — neuroscience — Posted on 2024-07-23

1655 Human iPSC-derived myelinating organoids andgloboid cells to study Krabbe Disease

Evans, L. M. P.; Gawron, J.; Sim, F.; Feltri, M. L.; Marziali, L. N.

10.1101/2024.07.19.604372 — neuroscience — Posted on 2024-07-23

1656 Distinct computational mechanisms of uncertainty processing explain opposing exploratory behaviors in anxiety and apathy

Yan, X.; Ebitz, B.; Grissom, N.; Darrow, D.; Herman, A.

10.1101/2024.06.04.597412 — neuroscience — Posted on 2024-07-23

1657 A septo-hypothalamic-medullary circuit directs stress-induced analgesia

Shah, D. P.; Sharma, P. R.; Agarwal, R.; Barik, A.

10.1101/2023.01.30.526171 — neuroscience — Posted on 2024-07-23

1658 Modelling alcohol consumption in rodents using two-bottle choice home cage drinking and optional lickometry-based microstructural analysis

Hou, S.; Arce Soto, N. M.; Glover, E. J.

10.1101/2024.07.19.604367 — neuroscience — Posted on 2024-07-23

1659 High stakes slow responding, but do not help overcome Pavlovian biases in humans

Algermissen, J.; den Ouden, H. E. M.

10.1101/2023.12.26.573351 — neuroscience — Posted on 2024-07-23

1660 Proteome-wide 4-hydroxy-2-nonenal signature of oxidative stress in the marine invasive tunicate Botryllus schlosseri

Kültz, D.; Gardell, A. M.; DeTomaso, A.; Stoney, G.; Rinkevich, B.; Qarri, A.; Hamar, J.

10.1101/2024.07.19.604351 — systems biology — Posted on 2024-07-23

1661 A transposable element insertion in IAA16 interrupts normal splicing and generates a novel dicamba resistance allele in Bassia scoparia

Montgomery, J. S.; Soni, N.; Marques Hill, S.; Morran, S.; Patterson, E.; Edwards, S.; Ratnayake, S.; Hung, Y.-H.; Pandesha, P. H.; Slotkin, R. K.; Dayan, F. E.; Gaines, T. A.

10.1101/2024.07.19.604363 — plant biology — Posted on 2024-07-23

1662 A tethering mechanism underlies Pin1-catalyzed proline cis-trans isomerization at a noncanonical site

Williams, C. C.; Chuck, J.; Munoz-Tello, P.; Kojetin, D.

10.1101/2024.07.19.604348 — biophysics — Posted on 2024-07-23

1663 Using deep learning predictions reveals a large number of register errors in PDB deposits

Sanchez Rodriguez, F.; Simpkin, A. J.; Chojnowski, G.; Keegan, R.; Rigden, D. J.

10.1101/2024.07.19.604304 — bioinformatics — Posted on 2024-07-23

1664 CGPA: multi-context insights from the cancer gene prognosis atlas

Cao, B.; Yu, X.; Gonzalez, G.; Murthy, A. R.; Li, T.; Shen, Y.; Yao, S.; Conejo-Garcia, J. R.; Jiang, P.; Wang, X.

10.1101/2024.07.19.604345 — bioinformatics — Posted on 2024-07-23

1665 AI-driven Discovery of Morphomolecular Signatures in Toxicology

Jaume, G.; Peeters, T.; Song, A. H.; Pettit, R.; Williamson, D. F. K.; Oldenburg, L.; Vaidya, A.; De Brot, S.; Chen, R. J.; Thiran, J.-P.; Le, L. P.; Gerber, G.; Mahmood, F.

10.1101/2024.07.19.604355 — bioinformatics — Posted on 2024-07-23

1666 Strain Tracking with Uncertainty Quantification

Kim, Y.; Worby, C. J.; Acharya, S.; van Dijk, L. R.; Alfonsetti, D.; Gromko, Z. J.; Azimzadeh, P. N.; Dodson, K. W.; Gerber, G. K.; Hultgren, S. J.; Earl, A. M.; Berger, B.; Gibson, T. E.

10.1101/2023.01.25.525531 — bioinformatics — Posted on 2024-07-23

1667 Non-Invasive Quality Control of Organoid Cultures Using Mesofluidic CSTR Bioreactors and High-Content Imaging

Charles, S.; Jackson-Holmes, E.; Sun, G.; Zhou, Y.; Siciliano, B.; Niu, W.; Han, H.; Nikitina, A.; Kemp, M. L.; Wen, Z.; Lu, H.

10.1101/2024.07.19.604365 — bioengineering — Posted on 2024-07-23

1668 Hydrophilic/ Omniphobic droplet arrays for high-throughput and quantitative enzymology

Lee, B.; Sunden, F.; Miller, M.; Pak, B.; Krebber, A.; Lutz, S.; Fordyce, P. M.

10.1101/2024.07.19.604368 — bioengineering — Posted on 2024-07-23

1669 Ascorbic acid and gallic acid mitigate behavioural deficits and loss of cerebellar myelin induced by Bisphenol-A in Wistar rats.

Adigun, K. O.; Ehinmowo, M. I.; Folarin, O.; Adebiyi, O. E.

10.1101/2024.07.17.603899 — animal behavior and cognition — Posted on 2024-07-23

1670 Parallel patterns of cognitive aging in marmosets and macaques

Vanderlip, C. R.; Jutras, M. L.; Asch, P. A.; Zhu, S. Y.; Lerma, M. N.; Buffalo, E. A.; Glavis-Bloom, C.

10.1101/2024.07.22.604411 — animal behavior and cognition — Posted on 2024-07-23

1671 Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta

McIntyre, J.; Morrison, A.; Maitland, K.; Berger, D.; Price, D. R. G.; Dougan, S.; Grigoriadis, D.; Tracey, A.; Holroyd, N.; Bull, K.; Rose Vineer, H.; Glover, M. J.; Morgan, E. R.; Nisbet, A. J.; McNeilly, T.; Bartley, Y.; Sargison, N.; Bartley, D.; Berriman, M.; Cotton, J.; Devaney, E.; Laing, R.; Doyle, S. R.

10.1101/2024.07.22.603261 — genomics — Posted on 2024-07-23

1672 Biology of healthy aging: Biological hallmarks of stress resistance-related and unrelated to longevity in humans

Badial, K.; Lacayo, P.; Murakami, S.

10.1101/2024.07.19.604380 — genomics — Posted on 2024-07-23

1673 Evolution of fast-growing piscivorous herring in the young Baltic Sea

Goodall, J.; Pettersson, M. E.; Bergstrom, U.; Cocco, A. E.; Delling, B.; Heimbrand, Y.; Karlsson, M.; Larsson, J.; Waldetoft, H.; Wallberg, A.; Wennerstrom, L.; Andersson, L.

10.1101/2024.07.20.604447 — evolutionary biology — Posted on 2024-07-23

1674 When does stronger selection increase the probability of evolutionary rescue?

Xu, K.; Osmond, M.

10.1101/2024.07.19.604382 — evolutionary biology — Posted on 2024-07-23

1675 CTCF-DEPENDENT INSULATION OF Hoxb13 AND THE HETEROCHRONIC CONTROL OF TAIL LENGTH

Lopez-Delisle, L.; Zakany, J.; Bochaton, C.; OSTEIL, P.; Mayran, A.; Darbellay, F.; Mascrez, B.; Rekaik, H.; Duboule, D.

10.1101/2024.07.20.604409 — developmental biology — Posted on 2024-07-23

1676 Sub-chronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice

Trigg, N. A.; Schjenken, J. E.; Martin, J. H.; Skerrett-Byrne, D. A.; Smyth, S. P.; Bernstein, I. R.; Anderson, A. L.; Stanger, S. J.; Simpson, E. N. A.; Tomar, A.; Teperino, R.; Conine, C. C.; De Iuliis, G. N.; Roman, S. D.; Bromfield, E. G.; Dun, M. D.; Eamens, A. L.; Nixon, B.

10.1101/2024.07.22.604196 — cell biology — Posted on 2024-07-23

1677 A Comprehensive Framework for Spatio-Temporal Analysis of DNA Damage Foci in Tumor Spheroids.

CAZALES, M.; LIU, T.; Bernard, D.; JULLIEN, D.; LORENZO, C.

10.1101/2024.07.19.604255 — cell biology — Posted on 2024-07-23

1678 The kinesin Kip2 promotes microtubule growth using a bipartite polymerase module to deliver tubulin to microtubule plus-ends

Nadalis, S.; Neyret, A.; Abrieu, A.; Drechsler, H.; Liakopoulos, D.; Portran, D.

10.1101/2024.07.19.604271 — cell biology — Posted on 2024-07-23

1679 Lung structural cell dynamics are altered by influenza virus infection experience leading to rapid immune protection following viral re-challenge

10.1101/2024.07.20.604410 — immunology — Posted on 2024-07-23

1680 White matter tract crossing and bottleneck regions in the fetal brain

Calixto, C.; Soldatelli, M.; Li, B.; Pierotich, L.; Gholipour, A.; Warfield, S. K.; Karimi, D.

10.1101/2024.07.20.603804 — neuroscience — Posted on 2024-07-22

1681 Velocities of Hippocampal Traveling Waves Proportional to Their Coherence Frequency

Goelman, G.; Benoliet, T.; Israel, Z.; Heymann, S.; leon, J.; Ekstein, D.

10.1101/2024.07.21.604460 — neuroscience — Posted on 2024-07-22

1682 Longitudinal sequencing reveals polygenic andepistatic nature of genomic response to selection

Forsberg, S. K. G.; Melo, D.; Grenier, J.; Wolf, S.; Tang, M.; Henry, L.; Pallares, L. F.; Clark, A. G.; Ayroles, J. F.

10.1101/2024.07.22.604612 — evolutionary biology — Posted on 2024-07-22

1683 mRNA stability fine tunes gene expression in the developing cortex to control neurogenesis

Serdar, L.; Egol, J.; Lackford, B.; Bennett, B.; Hu, G.; Silver, D.

10.1101/2024.07.22.604643 — neuroscience — Posted on 2024-07-22

1684 Dynamic integration of cortical activity in the deep layer of the anterolateral superior colliculus

Sugino, H.; Tanno, S.; Yoshida, T.; Isomura, Y.; Hira, R.

10.1101/2024.07.20.604436 — neuroscience — Posted on 2024-07-22

1685 STK19 drives Transcription-Coupled Repair by stimulating repair complex stability, Pol II ubiquitylation and TFIIH recruitment

Ramadhin, A. R.; Lee, S.-H.; Zhou, D.; Salmazo, A.; Gonzalo-Hansen, C.; van Sluis, M.; Blom, C. M. A.; Janssens, R. C.; Raams, A.; Dekkers, D. H. W.; Bezstarosti, K.; Slade, D.; Vermeulen, W.; Pines, A.; Demmers, J. A.; Bernecky, C.; Sixma, T. K.; Marteijn, J. A.

10.1101/2024.07.22.604556 — molecular biology — Posted on 2024-07-22

1686 Year-round quantification, structure and dynamics of epibacterial communities from diverse macroalgae reveal a persistent core microbiota and strong host specificities

Brunet, M.; Le Duff, N.; Barbeyron, T.; THOMAS, F.

10.1101/2024.07.22.604553 — microbiology — Posted on 2024-07-22

1687 Gut and oral microbial community characterization from women with breast cancer, women with ductal carcinoma in situ, and healthy women reveals differences in gut but not oral microbiota

McCune, E.; Sharma, A.; Johnson, B.; O'Meara, T.; Theiner, S.; Campos, M.; Heditsian, D.; Brain, S.; Gilbert, J.; Esserman, L.; Campbell, M.

10.1101/2024.07.22.604621 — microbiology — Posted on 2024-07-22

1688 Identification of novel PfEMP1 variants containing domain cassettes 11, 15 and 8 that mediate the Plasmodium falciparum virulence-associated rosetting phenotype

McLean, F.; Omondi, B. R.; Diallo, N.; Otoboh, S.; Kifude, C.; Abdi, A.; Lim, R.; Otto, T.; Ghumra, A.; Rowe, A.

10.1101/2024.07.22.604565 — microbiology — Posted on 2024-07-22

1689 Binocular processing facilitates escape behavior through multiple pathways to the superior colliculus

Broersen, R.; Thompson, G.; Thomas, F.; Stuart, G. J.

10.1101/2024.07.22.604589 — neuroscience — Posted on 2024-07-22

1690 Super-resolution imaging of proteins inside live mammalian cells with mLIVE-PAINT

Bhaskar, H.; Gidden, Z.; Virdi, G.; Kleinjan, D.-J.; Rosser, S. J.; Gandhi, S.; Regan, L.; Horrocks, M. H.

10.1101/2024.07.22.604574 — synthetic biology — Posted on 2024-07-22

1691 Glutamine-addiction in cisplatin resistant cancer cells is mediated by SLC7A11 and can be targeted with asparaginase therapy

Wang, J.; Strauss, R.; Bartek, J.; Rudd, S. G.

10.1101/2024.07.19.604261 — cancer biology — Posted on 2024-07-22

1692 G-quadruplexes are a source of vulnerability in BRCA2 deficient granule cell progenitors and medulloblastoma

Keahi, D. L.; Sanders, M. A.; Paul, M. R.; Webster, A. L. H.; Fang, Y.; Wiley, T. F.; Shalaby, S.; Carroll, T. S.; Chandrasekharappa, S. C.; Sandoval-Garcia, C.; MacMillan, M. L.; Wagner, J. E.; Hatten, M. E.; Smogorzewska, A.

10.1101/2024.07.20.604431 — cancer biology — Posted on 2024-07-22

1693 Programmable Editing of Primary MicroRNA Switches Stem Cell Differentiation and Improves Tissue Regeneration

Truong, V. A.; Chang, Y.-H.; Tu, Y.; Nguyen, N. T. K.; Pham, N. N.; Chang, C.-W.; Chang, Y.-H.; Ngo, D. T. K.; Pham, D. H.; Tu, J.; Dang, Q. T.; Truong, V. A.; Hu, Y.-C.

10.1101/2024.07.19.604260 — bioengineering — Posted on 2024-07-22

1694 Bacillus toyonensis biovar Thuringiensis: an overlooked entomopathogen?

Sauka, D. H.; Del Valle, E. E.; Palma, L.

10.1101/2024.07.21.604280 — evolutionary biology — Posted on 2024-07-22

1695 STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair

van den Heuvel, D.; Rodriguez-Martinez, M.; van der Meer, P. J.; Nieto Moreno, N.; Park, J.; Kim, H.-S.; van Schie, J. J.; Wondergem, A. P.; D'Souza, A.; Yakoub, G.; Herlihy, A.; Kashyap, K.; Boissiere, T.; Walker, J.; Mitter, R.; Apelt, K.; de Lint, K.; Kirdok, I.; Ljungman, M.; Wolthuis, R. M.; Cramer, P.; Scharer, O. D.; Kokic, G.; Svejstrup, J. Q.; Luijsterburg, M. S.

10.1101/2024.07.22.604575 — molecular biology — Posted on 2024-07-22

1696 Molecular basis of enhanced GLP-1 signaling mediated by GLP-1(9-36) in conjunction with LSN3318839

Li, J.; Li, G.; Mai, Y.; Liu, X.; Yang, D.; Zhou, Q.; Wang, M.-W.

10.1101/2024.07.21.604514 — molecular biology — Posted on 2024-07-22

1697 Smooth Muscle Cells-Expressed Bmal1 Regulates Vascular Calcification Independent of the Canonical Circadian Pathway

He, M.; Sun, Y.; Huang, F.; Zhu, Z.; Velazquez-Miranda, E.; Chong, Z.; Chen, Y.

10.1101/2024.07.22.604443 — molecular biology — Posted on 2024-07-22

1698 Dual modes of DNA N6-methyladenine maintenance by distinct methyltransferase complexes

Wang, Y.; Nan, B.; Ye, F.; Zhang, Z.; Yang, W.; Pan, B.; Niu, J.; Ju, A.; Liu, Y.; Zhang, W.; Liu, Y.; Gao, S.

10.1101/2024.07.21.604504 — molecular biology — Posted on 2024-07-22

1699 Metabolomics profiling reveals association of fermented herbal feed additive, growth performance and gut microbiota in piglets

Xiao, R.; Wang, L.; Tang, Z.; Qian, X.; Wang, J.; Lian, Y.; Tang, J.; Xu, J.; Lin, Y.; Shi, B.; Xu, P.; Xiong, Q.

10.1101/2024.07.21.604508 — microbiology — Posted on 2024-07-22

1700 Unravelling Plankton Adaptation in Global Oceans through the Analysis of Lipidomes

Liu, W.; Henry, H. C.; Lipp, J. S.; Fredricks, H. F.; Van Mooy, B.; Hinrichs, K.-U.

10.1101/2024.07.22.604538 — microbiology — Posted on 2024-07-22

1701 Genetic diversity of Toscana virus glycoproteins affects the kinetics of virus entry and the infectivity of newly produced virions

Thiesson, A.; Confort, M.-P.; Desloire, S.; Kohl, A.; Arnaud, F.; Ratinier, M.

10.1101/2024.07.22.604564 — microbiology — Posted on 2024-07-22

1702 Inhibition of Fusarium oxysporum growth in banana by silver nanoparticles: in vitro and in vivo assays

Mendoza, N. V.; Yanez, P.; Magdama, F.; Pacheco, R.; Vielma, J.; Vanegas, M. E.; Pestryakov, A.; Bogdanchikova, N.; Chong-Aguirre, P.

10.1101/2024.07.22.604513 — microbiology — Posted on 2024-07-22

1703 Iron limitation differentially affects viral replication in key marine microbes

Yung, C. C. M.; Kelly, R. L.; Kauffman, K. M.; Cunningham, B.; Zimmerman, A.; Worden, A.; John, S. G.

10.1101/2024.07.22.604475 — microbiology — Posted on 2024-07-22

1704 ASO-enhancement of TARDBP exitron splicing mitigates TDP-43 proteinopathies

Yamagishi, T.; Koide, S.; Toyama, G.; Washida, A.; Yamada, Y.; Hanyu, R.; Nadbitova, E.; Koike, Y. M.; Konno, T.; Ishihara, T.; Kato, T.; Onodera, O.; Sugai, A.

10.1101/2024.07.22.604579 — neuroscience — Posted on 2024-07-22

1705 Gradual entry into carbon starvation decreases the death rate of Escherichia coli

Droghetti, R.; Gough, Z.; Allaei, H.; Schink, S.; Gerland, U.

10.1101/2024.07.18.604087 — physiology — Posted on 2024-07-22

1706 Initial TCR Signal Strength Imprints GATA3 and Tbet Expression Driving T-helper Cell Fate Decisions

Al-Aghbar, M. A.; Khan, T.; Espino Guarch, M.; Palmer, D. C.; van Panhuys, N.

10.1101/2024.07.18.604067 — immunology — Posted on 2024-07-22

1707 IL-4 receptor alpha blockade in mice reduces skin inflammation, systemic response and the atopic march.

Leyva-Castillo, J. M.; Geha, R. S.; Wong, D. S. H.

10.1101/2024.07.18.604194 — immunology — Posted on 2024-07-22

1708 Correlated spontaneous activity sets up multi-sensory integration in the developing higher-order cortex

Dwulet, J. M.; Zabouri, N.; Kirchner, J. H.; Wosniack, M. E.; Raspanti, A.; Kong, D.; Houwen, G. J.; Maldonado, P. P.; Lohmann, C.; Gjorgjieva, J.

10.1101/2024.07.19.603239 — neuroscience — Posted on 2024-07-22

1709 Association between genetic clades and cancer prevalence suggested by French-wide study of oncogenic small ruminant beta-retroviruses diversity

Riocreux-Verney, B.; Verneret, M.; Diesler, R.; Dolmazon, C.; Gineys, B.; Cadore, J.-L.; Turpin, J.; Leroux, C.

10.1101/2024.07.18.604097 — pathology — Posted on 2024-07-22

1710 Lipid droplet surface promotes three-dimensional morphological evolution of non-rhomboidal cholesterol crystals

Lee, H.-R.; Kang, S.; Choi, S. Q.

10.1101/2024.07.18.604130 — biophysics — Posted on 2024-07-22

1711 MR Corge: Sensitivity analysis of Mendelian randomization based on the core gene hypothesis for polygenic exposures

Zhang, W.; Su, C.-Y.; Yoshiji, S.; Lu, T.

10.1101/2024.07.18.604191 — bioinformatics — Posted on 2024-07-22

1712 CytoNormPy enables a fast and scalable removal of batch effects in cytometry datasets.

Exner, T.; Hackert, N. S.; Leomazzi, L.; Van Gassen, S.; Saeys, Y.; Lorenz, H.-M.; Grieshaber-Bouyer, R.

10.1101/2024.07.19.604225 — bioinformatics — Posted on 2024-07-22

1713 Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally-defined K63-Polyubiquitylated Linker Histone H1

Shi, Q.; Deng, Z.; Zhang, L.; Tong, Z.; Li, J.-B.; Chu, G.-C.; Ai, H.; Liu, L.

10.1101/2024.07.22.604500 — biochemistry — Posted on 2024-07-22

1714 A pan-cancer gamma delta T cell repertoire

Yu, X.; Song, L.; Cen, L.; Cao, B.; Tao, R.; Shen, Y.; Abate-Daga, D.; Rodriguez, P. C.; Conejo-Garcia, J. R.; Wang, X.

10.1101/2024.07.18.604205 — genomics — Posted on 2024-07-22

1715 Evaluation of false positive and false negative errors in targeted next generation sequencing

Moon, Y.; Kim, Y.-H.; Kim, J.-K.; Hong, C. H.; Kang, E.-K.; Choi, H. W.; Lee, D.-e.; Kim, T.-M.; Heo, S. G.; Han, N.; Hong, K.-M.

10.1101/2024.07.22.603478 — genomics — Posted on 2024-07-22

1716 SCAR-6 elncRNA locus epigenetically regulates PROZ and modulates coagulation and vascular function

Ranjan, G.; Sehgal, P.; Scaria, V.; Sivasubbu, S.

10.1101/2024.07.21.604148 — genetics — Posted on 2024-07-22

1717 Investigating the role of RNA-binding protein Ssd1 in aneuploidy tolerance through network analysis

Dutcher, H. A.; Gasch, A. P.

10.1101/2024.07.19.604323 — genetics — Posted on 2024-07-22

1718 Temporal Transcriptomic Profiling of the Developing Xenopus laevis Eye

Hack, S. J.; Petereit, J.; Tseng, K. A.-S.

10.1101/2024.07.20.603187 — developmental biology — Posted on 2024-07-22

1719 Conserved signals orchestrate self-organization and symmetry breaking of bi-layered epithelia during development and regeneration

Journot, R. P.; Huyghe, M.; Barthelemy, A.; Couto-Moreira, H.; Sumbal, J.; Faraldo, M. M.; Dubail, M.; Fouillade, C.; Fre, S. P.

10.1101/2024.07.21.603898 — developmental biology — Posted on 2024-07-22

1720 How do we imagine a speech? A triple network model for situationally simulated inner speech

Gao, X.; Yang, J.; Li, C.; Guo, X.; Wang, Y.; Qu, Z.; Li, W.; Liu, J.; Li, Z.; Li, W.; Hu, Z.; Li, J.; Huang, Y.; Chen, J.; Wen, H.; Zhao, Z.; Kaiser, D.; Wei, T.; Yuan, B.

10.1101/2024.07.18.604038 — neuroscience — Posted on 2024-07-22

1721 CB-1 receptor agonist drastically changes oscillatory activity, defining active sleep

Topchiy, I.; Kocsis, B.

10.1101/2024.07.18.604173 — neuroscience — Posted on 2024-07-22

1722 DREAMER: Exploring Common Mechanisms of Adverse Drug Reactions and Disease Phenotypes through Network-Based Analysis

Firoozbakht, F.; Elkjaer, M. L.; Handy, D.; Wang, R.; Chervontseva, Z.; Rarey, M.; Loscalzo, J.; Baumbach, J.; Tsoy, O.

10.1101/2024.07.20.602911 — systems biology — Posted on 2024-07-22

1723 CoDIAC: A comprehensive approach for interaction analysis reveals novel insights into SH2 domain function and regulation

Kandoor, A.; Martinez, G.; Hitchcock, J. M.; Angel, S.; Campbell, L.; Rizvi, S.; Naegle, K. M.

10.1101/2024.07.18.604100 — systems biology — Posted on 2024-07-22

1724 The guardians of mitochondrial dynamics: a novel role for intermediate filament proteins

Hemel, I. M.; Steen, C.; Denil, S. L.; Ertaylan, G.; Kutmon, M.; Adriaens, M.; Gerards, M.

10.1101/2024.07.19.604282 — systems biology — Posted on 2024-07-22

1725 Dynamic photosynthetic labelling and carbon-positional mass spectrometry monitor in vivo carbon assimilation rates by ribulose-1,5-bisphosphate carboxylase.

Rajarathinam, Y.; Wittemeier, L.; Gutekunst, K.; Hagemann, M.; Kopka, J.

10.1101/2024.07.18.604122 — plant biology — Posted on 2024-07-22

1726 Unraveling the in planta growth of the plant pathogen Ralstonia pseudosolanacearum by mathematical modeling

Baroukh, C.; Gerlin, L.; Escourrou, A.; Genin, S.

10.1101/2024.07.18.604046 — plant biology — Posted on 2024-07-22

1727 Effects of Age and Diet on Triglyceride Metabolism in Mice

Spitler, K. M.; Shetty, S. K.; Davies, B. S.

10.1101/2024.07.19.602944 — physiology — Posted on 2024-07-22

1728 Network-based investigation of petroleum hydrocarbons-induced ecotoxicological effects and their risk assessment

Sahoo, A. K.; Madgaonkar, S. R.; Chivukula, N.; Karthikeyan, P.; Ramesh, K.; Marigoudar, S. R.; Sharma, K. V.; Samal, A.

10.1101/2024.07.18.604159 — pharmacology and toxicology — Posted on 2024-07-22

1729 Validation of an MPS based intestinal cell culture model for the evaluation of drug-induced toxicity

Hoffmann, S.; Hewitt, P.; Koscielski, I.; Kurek, D.; Strijker, W.; Kosim, K.

10.1101/2024.07.18.604106 — pharmacology and toxicology — Posted on 2024-07-22

1730 γ-aminobutyric acid receptor B signaling drives glioblastoma in females in an immune-dependent manner

Pathak, A.; Palasalava, S.; Knott, M. V.; Colon, B.; Ciervo, E.; Zhou, Y.; Mitchell, J.; Pumar, O. T.; Wong, H. K. A.; Zhang, L.; Susic, N.; Shah, K. H.; Kay, K.; Chin, D.; Johnson, S.; Cheng, F.; Lyssiotis, C. A.; Watson, D. C.; Ceccarelli, M.; Shah, A.; Wahl, D.; Lathia, J.; Bayik, D.

10.1101/2024.07.18.603996 — cancer biology — Posted on 2024-07-22

1731 Ru(II)-Photoactive Agents for Targeting ER Stress and Immunogenic Cell Death

Denison, M.; Ullrich, A.; Herroon, M.; Mecca, S.; Turro, C.; PODGORSKI, I.; Gibson, H. M.; Kodanko, J. J.

10.1101/2024.07.18.604104 — cancer biology — Posted on 2024-07-22

1732 Cell cycle expression heterogeneity predicts degree of differentiation

Noller, K.; Cahan, P.

10.1101/2024.07.19.604184 — bioinformatics — Posted on 2024-07-22

1733 In the AlphaFold era, when is experimental phasing of protein crystals still required?

Keegan, R.; Simpkin, A. J.; Rigden, D. J.

10.1101/2024.07.19.604295 — bioinformatics — Posted on 2024-07-22

1734 Rapid and accurate genotype imputation from low coverage short read, long read, and cell free DNA sequence

Li, Z.; Albrechtsen, A.; Davies, R. W.

10.1101/2024.07.18.604149 — bioinformatics — Posted on 2024-07-22

1735 Gencube: Efficient retrieval, download, and unification of genomic data from leading biodiversity databases

Son, K. H.; Cho, J.-Y.

10.1101/2024.07.18.604168 — bioinformatics — Posted on 2024-07-22

1736 Ex vivo model of breast cancer cell invasion in live lymph node tissue

Morgaenko, K.; Arneja, A.; Ball, A. G.; Putelo, A. M.; Munson, J. M.; Rutkowski, M. R.; Pompano, R. R.

10.1101/2024.07.18.601753 — bioengineering — Posted on 2024-07-22

1737 Tunable bicontinuous macroporous cell culture scaffolds via kinetically controlled phase separation

Dudaryeva, O. Y.; Cousin, L.; Krajnovic, L.; Groebli, G.; Sapkota, V.; Ritter, L.; Deshmukh, D.; Style, R. W.; Levato, R.; Labouesse, C.; Tibbitt, M. W.

10.1101/2024.07.18.604180 — bioengineering — Posted on 2024-07-22

1738 LCSKPOA: Enabling banded semi-global partial order alignments via efficient and accurate backbone generation through extended lcsk++

Weerakoon, M.; Saunders, C. T.; Heaton, H.

10.1101/2024.07.18.604181 — genomics — Posted on 2024-07-22

1739 An application of the MR-Horse method to reduce selection bias in genome-wide association studies of disease progression

Donovan, K.; Torres, J.; Zhu, D.; Herrington, W. G.; Staplin, N.

10.1101/2024.07.19.604143 — genetics — Posted on 2024-07-22

1740 Waves of Colonization and Gene Flow in a Great Speciator

Gyllenhaal, E. F.; Brady, S. S.; DeCicco, L. H.; Naikatini, A.; Hime, P. M.; Manthey, J. D.; Kelly, J. K.; Moyle, R. G.; Andersen, M. J.

10.1101/2024.07.18.603796 — evolutionary biology — Posted on 2024-07-22

1741 Gene expression evolution is predicted by selection, genetic covariance and network topology

Koch, E. L.; Rocabert, C.; Beeravolu Reddy, C.; Guillaume, F.

10.1101/2024.07.22.604294 — evolutionary biology — Posted on 2024-07-22

1742 Developmental small RNA transcriptomics reveals divergent evolution of the conserved microRNA miR-100 and the let-7-complex in nematodes

Sharma, D. R.; Röseler, W.; Witte, H.; Werner, M. S.; Sommer, R. J.

10.1101/2024.07.19.604269 — evolutionary biology — Posted on 2024-07-22

1743 Positive and negative selective assortment in pairwise interactions

Izquierdo, S.; Izquierdo, L.; Hauert, C.

10.1101/2024.07.18.604169 — evolutionary biology — Posted on 2024-07-22

1744 How genotype-by-environment interactions can maintain variation in mutualisms

Carlson, C. I.; Frederickson, M. E.; Osmond, M. M.

10.1101/2024.07.19.604331 — evolutionary biology — Posted on 2024-07-22

1745 Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape

Tennant, W. S. D.; Cardinale, E.; Moutroifi, Y.; Spencer, S. E.; Charafouddine, O.; Tildesley, M. J.; Metras, R.

10.1101/2024.07.18.604096 — ecology — Posted on 2024-07-22

1746 Massive presence of the invasive Polydora websteri (Polychaeta: Spionidae) in the North Adriatic Sea (Mediterranean Sea)

Lezzi, M.; Mazziotti, C.

10.1101/2024.07.18.603787 — ecology — Posted on 2024-07-22

1747 Keeping common species common: the role of future climate refugee in species conservation

Serafini, C.; Santostasi, N. L.; Canestrelli, D.; Ficetola, G. F.; Maiorano, L.

10.1101/2024.07.19.602245 — ecology — Posted on 2024-07-22

1748 Modelling genetic risk of β-cell dysfunction in human induced pluripotent stem cells from patients carrying the MTNR1B risk variant.

10.1101/2024.07.19.603674 — cell biology — Posted on 2024-07-22

1749 Live-cell imaging of pathogenic fungal hyphae reveal dynamic cellular responses to clinical antifungals

Thomson, D. D.; Inman, R.; Bignell, E.

10.1101/2024.07.19.602466 — cell biology — Posted on 2024-07-22

1750 The cGAS-STING Pathway Is Essential in Acute Ischemia-Induced Neutropoiesis and Neutrophil Priming in the Bone Marrow

Zhu, J.; Ruan, X.; Mangione, M. C.; Parra, P.; Su, X.; Luo, X.; Cao, D.

10.1101/2024.07.18.604120 — immunology — Posted on 2024-07-22

1751 Phase transition of WTAP regulates m6A modification of interferon-stimulated genes

Cai, S.; Zhou, J.; Luo, X.; Zhang, C.; Jin, S.; Ren, J.; Cui, J.

10.1101/2024.07.18.604157 — immunology — Posted on 2024-07-22

1752 NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in the intestinal epithelium

Mazzone, R. J.; Winsor, N. J.; Li, L. Y.; Barry, K. T.; Ranger, A.; Goyal, S.; Meade, J. J.; Bruce, J.; Philpott, D.; Girardin, S. E.

10.1101/2024.07.18.604161 — immunology — Posted on 2024-07-22

1753 Bona fide cytotoxic iNKT cells with superior antitumour responses identified in mice and humans

de Amat Herbozo, C.; Wong, S. W.; Kuypers, M.; Ilango, G.; Liu, Z.; Matthews, J. A.; Nguyen, A.; Veillette, A.; Gommerman, J. L.; Baranek, T.; Crome, S. Q.; Tsao, M. S.; Sacher, A. G.; Paget, C.; Mallevaey, T.

10.1101/2024.07.18.603987 — immunology — Posted on 2024-07-22

1754 Oestrogen influences B cell class-switching in individuals with an XX sex chromosome complement

10.1101/2024.07.18.604160 — immunology — Posted on 2024-07-22

1755 The Origin of Cognitive Modules for Face Processing: A Computational Evolutionary Perspective

Liu, J.; Wang, X.; Liu, J.

10.1101/2024.07.18.604211 — neuroscience — Posted on 2024-07-22

1756 TREM2 expression level is critical for microglial state, metabolic capacity and efficacy of TREM2 agonism

Feiten, A. F.; Dahm, K.; van Lengerich, B.; Suh, J. H.; Reifschneider, A.; Wefers, B.; Bartos, L. M.; Wind-Mark, K.; Schlepckow, K.; Ulas, T.; De-Domenico, E.; Becker, M.; Khalin, I.; Davis, S. S.; Wurst, W.; Plesnila, N.; Neher, J. J.; Brendel, M.; Lewcock, J. W.; Di Paolo, G.; Capell, A.; Monroe, K. M.; Schultze, J. L.; Haass, C.

10.1101/2024.07.18.604115 — neuroscience — Posted on 2024-07-22

1757 Precuneus activity during retrieval is positively associated with amyloid burden in cognitively normal older APOE4 carriers

Fischer, L.; Molloy, E. N.; Pichet Binette, A.; Vockert, N.; Marquardt, J.; Pacha Pilar, A.; Kreissl, M. C.; Remz, J.; Poirier, J.; Rajah, M. N.; Villeneuve, S.; PREVENT-AD Research Group, ; Maass, A.

10.1101/2024.07.18.604145 — neuroscience — Posted on 2024-07-22

1758 The interpretation attributed to observed gaze shifts affects their social-cueing effect

Zehngut, A.; Yuval-Greenberg, S.

10.1101/2024.07.18.603902 — neuroscience — Posted on 2024-07-22

1759 Freestanding rGO electrodes with tunable porous structures for improved neural recording

Dong, M.; Yang, J.; Zhen, F.; Du, Y.; Ding, S.; Yu, A.; Zou, R.; Qiu, L.; Guo, Z.; Coleman, H. A.; Parkington, H. C.; Fallon, J. B.; Forsythe, J. S.; Liu, M.

10.1101/2024.07.18.603459 — neuroscience — Posted on 2024-07-22

1760 ARGX-119, a therapeutic agonist antibody targeting MuSK

Vanhauwaert, R.; Oury, J.; Vankerckhoven, B.; Steyaert, C.; Jensen, S. M.; Vergoossen, D. L. E.; Kneip, C.; Santana, L.; Lim, J. L.; Plomp, J. J.; Augustinus, R.; Koide, S.; Blanchetot, C.; Ulrichts, P.; Huijbers, M. G.; Silence, K.; Burden, S. J.

10.1101/2024.07.18.604166 — neuroscience — Posted on 2024-07-22

1761 Circulating Myeloid-Derived Suppressor Cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosis

Serrano-Regal, M. P.; Camacho-Toledano, C.; Alonso-Garcia, I.; Ortega, M. C.; Machin-Diaz, I.; Lebron-Galan, R.; Garcia-Arocha, J.; Calahorra, L.; Clemente, D.

10.1101/2024.07.18.604171 — neuroscience — Posted on 2024-07-22

1762 Multi-Omic Analysis Reveals Lipid Dysregulation Associated with Mitochondrial Dysfunction in Parkinson's Disease Brain

Hallqvist, J.; Toomey, C. E.; Pinto, R.; Wernick, A.; Shahrani, M.; Heales, S.; Eaton, S.; Mills, K.; Gandhi, S.; Heywood, W. E.

10.1101/2024.07.18.604051 — neuroscience — Posted on 2024-07-22

1763 Inhibition of nitric oxide synthase transforms carotid occlusion-mediated benign oligemia into de novo large cerebral infarction

Kim, H.; Chung, J.; Kang, J. W.; Schellingerhout, D.; Lee, S. J.; Jang, H. J.; Park, I.; Kim, T.; Gwak, D.-S.; Lee, J. S.; Hong, S.-H.; Je, K.-H.; Bae, H.-J.; Sung, J.; Lo, E. H.; Faber, J.; Ayata, C.; Kim, D.-E.

10.1101/2024.07.18.604214 — neuroscience — Posted on 2024-07-22

1764 Deep Neural Networks to Register and Annotate the Cells of the C. elegans Nervous System

Atanas, A. A.; Lu, A. K.-Y.; Kim, J.; Baskoylu, S.; Kang, D.; Kramer, T. S.; Bueno, E.; Wan, F. K.; Flavell, S. W.

10.1101/2024.07.18.601886 — neuroscience — Posted on 2024-07-22

1765 Automated preparation of plasma lipids, metabolites, and proteins for LC/MS-based analysis of a high-fat diet in mice

Vu, N.; Maile, T. M.; Gullapudi, S.; Gaun, A.; Seitzer, P.; O'Brien, J. J.; Hackett, S. R.; Zavala-Solorio, J.; McAllister, F. E.; Kolumam, G.; Keyser, R.; Bennett, B. D.

10.1101/2024.07.18.602745 — physiology — Posted on 2024-07-22

1766 Exploring the Mechanism of Gentiana in Treating Pancreatic Cancer Based on Network Pharmacology and Molecular Docking Techniques

Qian, Y.; Wang, Z.; Ji, J.

10.1101/2024.07.18.604197 — pharmacology and toxicology — Posted on 2024-07-22

1767 A mouse model of cardiac AL amyloidosis unveils mechanisms of tissue accumulation and toxicity of amyloid fibrils

Martinez-Rivas, G.; Ayala, M. V.; Bender, S.; Codo, G. R.; Swiderska, K. W.; Lampis, A.; Pedroza, L.; Merdanovic, M.; Sicard, P.; Pinault, E.; Richard, L.; Lavatelli, F.; Canetti, D.; Rinsant, A.; Sihem, K.; Ory, C.; Oblet, C.; Pollet, J.; Naser, E.; Carpinteiro, A.; Roussel, M.; Javaugue, V.; Jaccard, A.; Bonaud, A.; Delpy, L.; Ehrmann, M.; Bridoux, F.; Sirac, C.

10.1101/2024.07.18.604040 — pathology — Posted on 2024-07-22

1768 Sex-Specific Changes in Cardiac Function and Electrophysiology During Progression of Adenine-Induced Chronic Kidney Disease in Mice

Dargam, V.; Sanchez, A.; Kolengaden, A.; Perez, Y.; Arias, R.; Valentin Cabrera, A. M.; Chaparro, D.; Tarafa, C.; Coba, A.; Yapaolo, N.; Todd, E. A.; Williams, M. M.; Shehadeh, L. A.; Hutcheson, J. D.

10.1101/2024.07.18.604201 — pathology — Posted on 2024-07-22

1769 Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

Cunningham, C. E.; Vizeacoumar, F. S.; Zhang, Y.; Kyrylenko, L.; Gao, P.; Maranda, V.; Dong, H.; Price, J. D.; Ganapathysamy, A.; Hari, R.; Denomy, C.; Both, S.; Wagner, K.; Wu, Y.; Khan, F.; Mosley, S.; Chen, A.; Katrii, T.; Zoller, B. G.; Rajamanickam, K.; Walke, P.; Gong, L.; Patel, H.; Lazell-Wright, M.; Morejon Morales, A.; Bhanumathy, K. K.; Elhasasna, H.; Dahiya, R.; Abuhussein, O.; Dmitriev, A.; Freywald, T.; Prando Munhoz, E.; Krishnan, A.; Ruppin, E.; Lee, J. S.; Rox, K.; Toosi, B.; Koebel, M.; Kinloch, M.; Hopkins, L.; Lee, C. H.; Datla, R.; Yadav, S.; Wu, Y.; Baker, K.; Empting, M.

10.1101/2024.07.18.603978 — cancer biology — Posted on 2024-07-22

1770 Vortex light field microscopy: 3D spectral single-molecule imaging with a twist

Zhang, B.; Daly, S.; Zhu, C.; Lenz, M. O.; Weiss, L. E.; Needham, L.-M.; Peters, R.; Lee, S.; O'Holleran, K.

10.1101/2024.07.18.604091 — biophysics — Posted on 2024-07-22

1771 AlphaFold Model Quality Self-Assessment Improvement Via Deep Graph Learning

Verburgt, J.; Zhang, Z.; Kihara, D.

10.1101/2024.07.18.604136 — bioinformatics — Posted on 2024-07-22

1772 Multiple Independent Genetic Code Reassignments of the UAG Stop Codon in Phyllopharyngean Ciliates

McGowan, J.; Richards, T. A.; Hall, N.; Swarbreck, D.

10.1101/2024.07.18.603678 — evolutionary biology — Posted on 2024-07-22

1773 Meiosis-specific decoupling of the pericentromere from the kinetochore

Pan, B.; Bruno, M.; Macfarlan, T. S.; Akera, T.

10.1101/2024.07.21.604490 — cell biology — Posted on 2024-07-22

1774 Membranous translation platforms in the chloroplast of Chlamydomonas reinhardtii

Sun, Y.; Bakhtiari, S.; Valente-Paterno, M.; Jiang, H.; Zerges, W.

10.1101/2024.07.22.604633 — cell biology — Posted on 2024-07-22

1775 A high-resolution model of gene expression during Gossypium hirsutum (cotton) fiber development

Grover, C. E.; Jareczek, J. J.; Swaminathan, S.; Lee, Y.; Howell, A. H.; Rani, H.; Arick, M. A.; Leach, A. G.; Miller, E. R.; Yang, P.; Hu, G.; Xiong, X.; Mallery, E. L.; Peterson, D. G.; Xie, J.; Haigler, C. H.; Zabotina, O. A.; Szymanski, D. B.; Wendel, J. F.

10.1101/2024.07.20.604417 — cell biology — Posted on 2024-07-22

1776 Secreted exosomes induce filopodia formation

McAtee, C.; Patel, M. R.; Hoshino, D.; Sung, B. H.; von Lersner, A. K.; Shi, M.; Hong, N. H.; Young, A.; Krystofiak, E.; Zijlstra, A.; Weaver, A. M.

10.1101/2024.07.20.604139 — cell biology — Posted on 2024-07-22

1777 Classification of human actin pathological variants using C. elegans CRISPR-generated models

Hecquet, T.; Arbogast, N.; Suhner, D.; Goetz, A.; Amann, G.; Yürekli, S.; Marangoni, F.; Greve, J. N.; Di Donato, N.; Reymann, A.-C.

10.1101/2024.07.22.604239 — cell biology — Posted on 2024-07-22

1778 Rapalink-1 reveals novel mTOR-dependent genes and the role of agmatinases in cellular growth and chronological lifespan

Kumar, J.; Rallis, C.

10.1101/2024.07.20.604404 — cell biology — Posted on 2024-07-22

1779 Cell State-Specific Cytoplasmic Material Properties Control Spindle Architecture and Scaling

Kletter, T.; Munoz, O.; Reusch, S.; Biswas, A.; Halavatyi, A.; Neumann, B.; Kuropka, B.; Zaburdaev, V.; Reber, S.

10.1101/2024.07.22.604615 — cell biology — Posted on 2024-07-22

1780 Tumor-derived colorectal cancer organoids induce a unique Treg cell population through direct modulation of CD4+ T cell differentiation.

Aristin Revilla, S.; Frederiks, C. L.; Prekovic, S.; Mocholi, E.; Kranenburg, O.; Coffer, P. J.

10.1101/2024.07.18.604049 — immunology — Posted on 2024-07-22

1781 Bone pain in Fibrous dysplasia does not rely on aberrant sensory nerve sprouting or neuroma formation

Palmisano, B.; Tavanti, C.; Farinacci, G.; Gosti, G.; Leonetti, M.; Donsante, S.; Giannicola, G.; Appelman-Dijkstra, N.; Corsi, A.; Ippolito, E.; Riminucci, M.

10.1101/2024.07.18.603554 — pathology — Posted on 2024-07-22

1782 An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia

Diz, M. T.; Reglero, C.; Falkenstein, C. D.; Castro, A.; Hayer, K. E.; Radens, C.; Quesnel-Vallieres, M.; Ang, Z.; Sehgal, P.; Li, M. M.; Barash, Y.; Tasian, S. K.; Ferrando, A.; Thomas-Tikhonenko, A.

10.1101/2023.09.14.557413 — cancer biology — Posted on 2024-07-22

1783 In-Silico Analyses of Molecular Force Sensors for Mechanical Characterization of Biological Systems

Lopez, D. M.; Castro, C. E.; Sotomayor, M.

10.1101/2024.07.17.603923 — biophysics — Posted on 2024-07-22

1784 Prediction of inhibitory peptides against E. coli with desired MIC value

Bajiya, N.; Kumar, N.; Raghava, G. P. S.

10.1101/2024.07.18.604028 — bioinformatics — Posted on 2024-07-22

1785 PAC-MAP: Proximity Adjusted Centroid Mapping for Accurate Detection of Nuclei in Dense 3D Cell Systems

Van De Looverbosch, T.; De Beuckeleer, S.; De Smet, F.; Sijbers, J.; De Vos, W.

10.1101/2024.07.18.602066 — bioinformatics — Posted on 2024-07-22

1786 scEccDNAdb: an integrated single-cell eccDNA resource for human and mouse

wang, w.; Zhao, X.; Ma, T.; Zung, T.; Yang, Y.; Guo, Y.; guo, z.

10.1101/2024.07.18.604058 — bioinformatics — Posted on 2024-07-22

1787 Choose your partner: Social evaluation of skilfulness at cooperative co-action tasks in Tonkean macaques (Macaca tonkeana)

Hirel, M.; Meunier, H.; Mundry, R.; Rakoczy, H.; Fischer, J.; Keupp, S.

10.1101/2024.07.18.604048 — animal behavior and cognition — Posted on 2024-07-22

1788 Advancing the Indian Cattle Pangenome: Characterizing Non-Reference Sequences in Bos indicus

Azam, S.; Sahu, A.; Pandey, N. K.; Neupane, M.; Tassel, C. P. V.; Rosen, B. D.; Gandham, R. K.; Rath, S. N.; Majumdar, S. S.

10.1101/2024.07.18.604025 — genomics — Posted on 2024-07-22

1789 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Phan-Canh, T.; Mair, T.; Miccolo, C.; Drino, A.; Doni, M.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.

10.1101/2024.02.01.577722 — genetics — Posted on 2024-07-22

1790 Selection for greater dispersal in early life leads to increased rate of age-dependent decline in locomotor activity and shorter lifespan

Ruchitha, B. G.; Kumar, N.; Sura, C.; Tung, S.

10.1101/2022.07.03.498422 — evolutionary biology — Posted on 2024-07-22

1791 Navigating the Cold: Integrative Transcriptome Sequencing Approach Reveals Ionoregulatory and Whole-Body Responses to Cold Acclimation in Drosophila ananassae

Grath, S.; Yılmaz, V. M.; Bao, Z.

10.1101/2024.07.18.604044 — evolutionary biology — Posted on 2024-07-22

1792 Linking Molecular Mechanisms to their Evolutionary Consequences: a primer

Grah, R.; Guet, C. C.; Tkacik, G.; Lagator, M.

10.1101/2024.07.18.604043 — evolutionary biology — Posted on 2024-07-22

1793 Is testing the bee-all and end-all of varroa eradication?

Abell, I. R.; Flegg, J. A.; Le, T. P.; Baker, C. M.

10.1101/2024.07.18.604034 — ecology — Posted on 2024-07-22

1794 Transcriptional, developmental, and functional parallels of lymphatic and venous smooth muscle

Arroyo Ataz, G.; Yague, A. C.; Breda, J. C.; Mazzilli, S. A.; Jones, D.

10.1101/2024.07.18.604042 — developmental biology — Posted on 2024-07-22

1795 Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase

Wang, Y.; Wang, G.; Zhang, L.; Cai, Q.; Lin, M.; Huang, D.; Xie, Y.; Lin, W.; Lin, X.

10.1101/2024.03.22.586220 — microbiology — Posted on 2024-07-22

1796 Leveraging Grating-Based Flickers: A Leap Toward Practical, Visually Comfortable, and High-Performance Dry EEG Code-VEP BCI

Dehais, F.; Cabrera Castillos, K.; Ladouce, S.; Clisson, P.

10.1101/2024.07.17.603960 — neuroscience — Posted on 2024-07-22

1797 The Three Stages of Learning to Master a Sensory Augmentation Device: Activation - Acquisition - Integration

Muehlinghaus, S.; Schmidt, V.; Koenig, P.

10.1101/2024.07.17.603884 — neuroscience — Posted on 2024-07-22

1798 Operation regimes of spinal circuits controlling locomotion and role of supraspinal drives and sensory feedback

Rybak, I. A.; Shevtsova, N. A.; Markin, S. N.; Prilutsky, B. I.; Frigon, A.

10.1101/2024.03.21.586122 — neuroscience — Posted on 2024-07-22

1799 Influence of temporal information gaps on decision making: describing the dynamics of working memory

Sospedra, A.; Canals, S.; Marcos, E.

10.1101/2024.07.17.603868 — neuroscience — Posted on 2024-07-22

1800 Dynamic regulation of H2A.Zub and H3K27me3 by ambient temperature in plant cell fate determination

Zhu, K.; Zhao, L.; Lu, F.; Lin, X.; He, C.; Wagner, D.; Xiao, J.

10.1101/2024.07.18.604029 — plant biology — Posted on 2024-07-22

1801 Neuroprotective Effects of Bioactive Molecules Derived from Tobacco as Potential Therapeutic Candidates for Alzheimer Disease

Liao, C.; Li, M.; Li, Z.; Wang, M.; Peng, Q.; Zhu, Z.; Wang, H.-H.; Guan, Y.

10.1101/2024.03.20.585935 — pharmacology and toxicology — Posted on 2024-07-22

1802 GFETM: Genome Foundation-based Embedded Topic Model for scATAC-seq Modeling

Fan, Y.; Osakwe, A.; Li, Y.; Ding, J.; Li, Y.

10.1101/2023.11.09.566403 — bioinformatics — Posted on 2024-07-22

1803 Synergistic Biophysics and Machine Learning Modeling to Rapidly Predict Cardiac Growth Probability

Oomen, P. J. A.; Jones, C. E.

10.1101/2024.07.17.603959 — bioengineering — Posted on 2024-07-22

1804 Robust data-driven segmentation of pulsatile cerebral vessels using functional magnetic resonance imaging

Wright, A. M.; Xu, T.; Ingram, J.; Koo, J.; Zhao, Y.; Tong, Y.; Wen, Q.

10.1101/2024.07.17.603932 — bioengineering — Posted on 2024-07-22

1805 Intravenous BCG induces a more potent airway and lung immune response than intradermal BCG in SIV-infected macaques

Jauro, S.; Larson, E. C.; Gleim, J. L.; Wahlberg, B. M.; Rodgers, M. A.; Chehab, J. C.; Lopez-Velazques, A. E.; Ameel, C. L.; Tomko, J. A.; Sakal, J. L.; DeMarco, T.; Jake Borish, H.; Maiello, P.; Potter, E. L.; Roederer, M.; Lin, P. L.; Flynn, J. L.; Scanga, C. A.

10.1101/2024.07.17.603921 — immunology — Posted on 2024-07-22

1806 Pre-stimulus Activity Mediates Event-Related Theta Synchronization and Alpha Desynchronization During Memory Formation in Healthy Aging

Strzelczyk, D.; Langer, N.

10.1101/2024.07.17.603896 — neuroscience — Posted on 2024-07-22

1807 Normative trajectories of R1, R2* and magnetic susceptibility in basal ganglia on healthy ageing

Chan, K.-S.; Zwiers, M. P.; Jansen, M. G.; Oosterman, J. M.; Norris, D. G.; Beckmann, C. F.; Marques, J. P.

10.1101/2024.07.17.603922 — neuroscience — Posted on 2024-07-22

1808 Ex vivo functional characterization of mouse olfactory bulb projection neurons reveals a heterogenous continuum

Gadiwalla, S.; Guillaume, C.; Huang, L.; White, S. J.; Basha, N.; Petersen, P.; Galliano, E.

10.1101/2024.07.17.603915 — neuroscience — Posted on 2024-07-22

1809 Sensory dependencies rapidly and autonomously yield generalizable representations in recurrent cortical-like networks

Rongala, U. B.; Jorntell, H.

10.1101/2024.07.17.603881 — neuroscience — Posted on 2024-07-22

1810 Tensor Kernel Learning for Classification of Alzheimer's Conditions using Multimodal Data

Vu, T. D.; Le, T. T.; Pham, T. M.; Nguyen, T. L.; Merai, K. A.; Adel, M.; Nguyen, D. V.; Nguyen, T. T.; Dinh, L. D.; Chen, O. Y.

10.1101/2024.07.17.603875 — neuroscience — Posted on 2024-07-22

1811 A powdery mildew core effector protein targets host endosome tethering complexes HOPS and CORVET

Sabelleck, B.; Deb, S.; Spanu, P. D.; Thordal-Christensen, H.; Panstruga, R.

10.1101/2024.07.17.603885 — plant biology — Posted on 2024-07-22

1812 Blocking the ability of huntingtin to bind membranes: a therapeutic strategy for Huntingtons disease

Siriwardhana, C.; Adegbuyiro, A.; Sedighi, F.; Stonebraker, A. R.; Leonard, S.; Beasley, M.; Skeens, A.; Mertz, B.; Geldenhuys, W. J.; Legleiter, J.

10.1101/2024.07.17.603089 — biophysics — Posted on 2024-07-22

1813 AliMarko: A Novel Tool for Eukaryotic Virus Identification Using Expert-Guided Approach

Popov, N.; Evdokimova, A.; Sonets, I.; Panova, V.; Molchanova, M.; Korneenko, E.; Manolov, A.; Ilina, E.

10.1101/2024.07.19.603887 — bioinformatics — Posted on 2024-07-22

1814 Utilization of a Human Liver Tissue Chip for Drug-Metabolizing Enzyme Induction Studies of Perpetrator and Victim Drugs

Ohri, S.; Parekh, P.; Nichols, L.; Rajan, S. A. P.; Cirit, M.

10.1101/2024.07.17.603946 — bioengineering — Posted on 2024-07-22

1815 Recording butterfly movements from a UAV

de Margerie, E.; Monmasson, K.

10.1101/2024.07.17.603869 — animal behavior and cognition — Posted on 2024-07-22

1816 Genetic and selective constraints on the optimization of gene product diversity

Jiang, D.; Kejiou, N.; Qiu, Y.; Palazzo, A. F.; Pennell, M.

10.1101/2024.07.17.603951 — evolutionary biology — Posted on 2024-07-22

1817 Effects of copepod chemical cues on intra- and extracellular toxins in two species of Dinophysis

Pourdanandeh, M.; Sechet, V.; Carpentier, L.; Reveillon, D.; Herve, F.; Hubert, C.; Hess, P.; Selander, E.

10.1101/2024.07.17.603891 — ecology — Posted on 2024-07-22

1818 Ecology and environment predict spatially stratified risk of highly pathogenic avian influenza in wild birds across Europe

Hayes, S.; Hilton, J.; Mould-Quevodo, J.; Donnelly, C.; Baylis, M.; Brierley, L.

10.1101/2024.07.17.603912 — ecology — Posted on 2024-07-22

1819 The distribution of the hemlock woolly adelgid in Canada.

MacQuarrie, C. J. K.; Gray, M.; Bullas-Appleton, E.; Kimoto, T.; Mielewczyk, N.; Neville, R.; Ogden, J. B.; Fidgen, J. G.; Turgeon, J. J.

10.1101/2024.07.18.604084 — ecology — Posted on 2024-07-22

1820 Metacommunity theory and metabarcoding reveal the environmental, spatial, and biotic drivers of meiofaunal communities in sandy beaches

Macher, J.-N.; Pichler, M.; Creer, S.; Martinez, A.; Fontaneto, D.; Renema, W.

10.1101/2024.07.17.603914 — ecology — Posted on 2024-07-22

1821 Thermal preconditioning modulates coral physiology and heat tolerance: A multi-species perspective

Ferrara, E. F.; Roik, A.; Woehrmann-Zipf, F.; Ziegler, M.

10.1101/2024.07.18.604102 — ecology — Posted on 2024-07-22

1822 SpeSpeNet: An interactive and user-friendly tool to create and explore microbial correlation networks

van Eijnatten, A. L.; van Zon, L.; Manousou, E.; Bikineeva, M.; Wubs, J.; van der Putten, W.; Morriën, E.; Dutilh, B. E.; Snoek, B. L.

10.1101/2024.07.17.603889 — ecology — Posted on 2024-07-22

1823 The role of polycystic kidney disease-like homologs in planarian nervous system regeneration and function

Ross, K. G.; Alvarez Zepeda, S.; Auwal, M. A.; Garces, A. K.; Roman, S.; Zayas, R. M.

10.1101/2024.07.17.603829 — developmental biology — Posted on 2024-07-22

1824 Atypical soluble guanylyl cyclases control brain size in Drosophila

Prieto, D.; Egger, B.; Cantera, R.

10.1101/2024.07.17.603894 — developmental biology — Posted on 2024-07-22

1825 Spike inference from mouse spinal cord calcium imaging data

Rupprecht, P.; Fan, W.; Sullivan, S. J.; Helmchen, F.; Sdrulla, A.

10.1101/2024.07.17.603957 — neuroscience — Posted on 2024-07-22

1826 An enhancer-AAV toolbox to target and manipulate distinct interneuron subtypes

Furlanis, E.; Dai, M.; Leyva Garcia, B.; Vergara, J.; Pereira, A.; Pelkey, K.; Tran, T.; Gorissen, B. L.; Vlacho, A.; Hairston, A.; Huang, S.; Dwivedi, D.; Du, S.; Wills, S.; McMahon, J.; Lee, A. T.; Chang, E. F.; Razzaq, T.; Qazi, A.; Vargish, G.; Yuan, X.; Caccavano, A.; Hunt, S.; Chittajallu, R.; McLean, N.; Hewit, L.; Paranzino, E.; Rice, H.; Cummins, A. C.; Plotnikova, A.; Mohanty, A.; Tangen, A. C.; Shin, J. H.; Azadi, R.; Eldridge, M. A. G.; Alvarez, V. A.; Averbeck, B. B.; Alyahyay, M.; Reyes Vallejo, T.; Soheib, M.; Vattino, L. G.; MacGregor, C. P.; Banks, E.; Olah, V. J.; Naskar, S.;

10.1101/2024.07.17.603924 — neuroscience — Posted on 2024-07-22

1827 Adolescent alcohol exposure alters age-related progression of behavioral and neurotrophic dysfunction in the TgF344-AD model in a sex-specific manner

Reitz, N. L.; Nunes, P. T.; Savage, L. M.

10.1101/2024.07.17.603911 — neuroscience — Posted on 2024-07-22

1828 PATJ regulates cell stress responses and vascular remodeling post-stroke

Zhang, M.; Jiang, W.; Arkelius, K.; Swanson, R. A.; Ma, D. K.; Singhal, N. S.

10.1101/2024.07.17.603777 — neuroscience — Posted on 2024-07-22

1829 A selective S-acyltransferase inhibitor suppresses tumor growth

Lee, J.-Y.; Dilones, S.; Maujean, T.; Asad, M.; Najar, M. A.; Auslander, N.; Brady, D. C.; Burslem, G. M.; Witze, E.

10.1101/2024.07.18.604152 — cancer biology — Posted on 2024-07-22

1830 EGFR does not directly interact with cortical actin: A SRRF'n'TIRF Study

Pandey, S.; Wohland, T.

10.1101/2024.07.20.604398 — biophysics — Posted on 2024-07-22

1831 WITHDRAWN: Anti-TNF-induced IL-27 modulates regulatory T cell responses in patients with IBD that respond to therapy

Sanches Peres, R.; Thomas, T.; Friedrich, M.; Pohin, M.; Pearson, C.; Ferreira, R.; Mann, E.; Trzupek, D.; Rich-Griffin, C.; Jainarayanan, A.; Jones, K.; Gu, Y.; Todd, J.; Uhlig, H.; Buckley, C.; Dendrou, C.; Travis, S.; Powrie, F.

10.1101/2022.11.21.517257 — immunology — Posted on 2024-07-22

1832 The N-terminal PAS domain directly regulates hERG channel gating in excised, inside-out patch-clamp fluorometry (PCF) recordings

TRUDEAU, M. C.

10.1101/2024.07.21.604498 — biophysics — Posted on 2024-07-22

1833 Structures of TGF-beta with betaglycan and the signaling receptors reveal the mechanism whereby betaglycan potentiates receptor complex assembly and signaling

Wieteska, L.; Taylor, A. B.; Punch, E.; Coleman, J. A.; Conway, I. O.; Lin, Y.-F.; Byeon, C.-H.; Hinck, C. S.; Krzysiak, T.; Ishima, R.; Lopez-Casillas, F.; Cherepanov, P.; Bernard, D. J.; Hill, C. S.; Hinck, A. P.

10.1101/2024.07.19.604101 — biophysics — Posted on 2024-07-22

1834 Comparison of Methodologies for Absolute Binding Free Energy Calculations of Ligands to Intrinsically Disordered Proteins

Papadourakis, M.; Cournia, Z.; Mey, A. S. J. S.; Michel, J.

10.1101/2024.07.19.604182 — biophysics — Posted on 2024-07-22

1835 Structural Basis for RNA-guided DNA degradation by Cas5-HNH/Cascade complex

Zhu, H.; Zhang, H.; Liu, Y.; Wang, L.; Zhang, Q.; Fu, P.; Zhang, L.

10.1101/2024.07.22.604555 — biophysics — Posted on 2024-07-22

1836 Amyloid fibril structures link CHCHD10 and CHCHD2 to neurodegeneration.

Lv, G.; Sayles, N. M.; Huang, Y.; Mancinelli, C. D.; McAvoy, K.; Shneider, N. A.; Manfredi, G.; Kawamata, H.; Eliezer, D.

10.1101/2024.07.18.604174 — biophysics — Posted on 2024-07-22

1837 Autoinhibition of cMyBP-C by its middle domains

Greenman, A. C.; Sadler, R. L.; Harris, S. P.

10.1101/2024.07.19.603145 — biophysics — Posted on 2024-07-22

1838 The structure of a NEMO construct engineered for screening reveals novel determinants of inhibition

Kenedy, A. E.; Barczewski, A. H.; Arnoldy, C. R.; Pennington, J. P.; Tiernan, K. A.; Hidalgo, M. B.; Reilly, C. C.; Ragusa, M. J.; Grigoryan, G.; Mierke, D. F.; Pellegrini, M.

10.1101/2024.07.18.604176 — biophysics — Posted on 2024-07-22

1839 Preparation of oxygen-sensitive proteins for high-resolution cryoEM structure determination using (an)aerobic blot-free vitrification

Cook, B. D.; Narehood, S. M.; McGuire, K. L.; Li, Y.; Tezcan, A. F.; Herzik, M. A.

10.1101/2024.07.19.604374 — biophysics — Posted on 2024-07-22

1840 Identification of Juglone, a "first-in-class" inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast-based high throughput screens

Suyal, S.; Bachhawat, A.; Choudhury, C.; Kaur, D.

10.1101/2024.07.21.604522 — biochemistry — Posted on 2024-07-22

1841 Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters

Depta, L.; Bryce-Rogers, H. P.; Dekker, N. J.; Bonke, A. W.; Camporese, N.; Qian, M.; Xu, Y.; Covey, D. F.; Laraia, L.

10.1101/2024.07.22.604041 — biochemistry — Posted on 2024-07-22

1842 Immersive exposure to simulated visual hallucinations modulates high-level human cognition

Greco, A.; Rastelli, C.; Ubaldi, A.; Riva, G.

10.1101/2024.07.17.603874 — animal behavior and cognition — Posted on 2024-07-22

1843 Cell state and transcription factor modulation during extended ex vivo CD8+ T-cell expansion.

Lui, Y.; Jenkins, E.; Ng, E. Z. Q.; Kotowski, M.; Mullin, S. J.; Clarke, J.; Davis, S. J.; Santos, A. M.; Sharma, S.

10.1101/2024.07.17.603780 — immunology — Posted on 2024-07-22

1844 Necrosis drives susceptibility to Mycobacterium tuberculosis in POLG mtDNA mutator mice

Mabry, C. J.; Weindel, C. G.; Stranahan, L. W.; Martinez, E. L.; VanPortfliet, J. J.; West, P. L.; Patrick, K. L.; Watson, R. O.

10.1101/2024.07.17.603991 — immunology — Posted on 2024-07-22

1845 Single cell RNA-sequencing reveals GINIP-expressing neurons as the main targets of focused ultrasound

Brunet, E.; Parpaite, T.; Yoo, S.; Debieu, E.; Metwally, K.; Mensah, S.; Malapert, P.; Saurin, A.; Macherey, O.; Franceschini, E.; Moqrich, A.

10.1101/2024.07.17.604026 — neuroscience — Posted on 2024-07-22

1846 Infant EEG microstate dynamics relate to fine-grained patterns of infant attention during naturalistic play with caregivers

Bagdasarov, A.; Markert, S.; Gaffrey, M. S.

10.1101/2024.07.20.604427 — neuroscience — Posted on 2024-07-22

1847 Acupuncture triggers earlier recovery from ischemic stroke than sham needling in a rat model

He, W.; Tang, H.; Li, J.; Shen, X.; Li, C.; Liu, H.; Yu, W.

10.1101/2024.07.14.601555 — neuroscience — Posted on 2024-07-22

1848 Label-free multiphoton imaging reveals volumetric shifts across development in sensory-related brain regions of a miniature transparent vertebrate

Tatarsky, R. L.; Akbari, N.; Wang, K.; Xu, C.; Bass, A. H.

10.1101/2024.07.18.604134 — neuroscience — Posted on 2024-07-22

1849 Identifying a ubiquitous gene expression variation pattern in the human brain

Lo, C.-M.; Duncan, N. W.

10.1101/2024.07.21.604497 — neuroscience — Posted on 2024-07-22

1850 Comparing diploid and triploid apples from a diverse collection

Greaves, E.; Davies, T.; Myles, S.; Migicovsky, Z.

10.1101/2024.07.17.603958 — plant biology — Posted on 2024-07-22

1851 Intestinal serotonergic vagal signaling as a mediator of microbiota-induced hypertension

de Araujo, A.; Sree Kumar, H.; Yang, T.; Alviter Plata, A.; Dirr, E. W.; Bearss, N.; Baekey, D. M.; Miller, D. S.; Donertas-Ayaz, B.; Ahmari, N.; Singh, A.; Kalinoski, A. L.; Garrett, T.; Martyniuk, C. J.; de Lartigue, G.; Zubcevic, J.

10.1101/2024.07.17.603451 — physiology — Posted on 2024-07-22

1852 Oxygen is Toxic in the Cold in C. elegans.

Suraci, C. M.; Morrison, M. L.; Roth, M. B.

10.1101/2024.07.17.603990 — physiology — Posted on 2024-07-22

1853 Integrating Phylogenies with Chronology to Assemble the Tree of Life

Barba-Montoya, J.; Craig, J. M.; Kumar, S.

10.1101/2024.07.17.603989 — bioinformatics — Posted on 2024-07-22

1854 Artifact-Minimized High-Ratio Image Compression with Preserved Analysis Fidelity

Duan, B.; Walker, L. A.; Xie, B.; Lee, W. J.; Lin, A.; Yan, Y.; Cai, D.

10.1101/2024.07.17.603794 — bioinformatics — Posted on 2024-07-22

1855 MENTOR: Multiplex Embedding of Networks for Team-Based Omics Research

Sullivan, K. A.; Miller, J. I.; Townsend, A.; Morgan, M.; Lane, M.; Pavicic, M.; Shah, M.; Cashman, M.; Jacobson, D. A.

10.1101/2024.07.17.603821 — bioinformatics — Posted on 2024-07-22

1856 Engineering Candida boidinii formate dehydrogenase for activity with NMN(H)

Vainstein, S.; Banta, S.

10.1101/2024.07.17.604001 — bioengineering — Posted on 2024-07-22

1857 Bioadhesive Hydrogel-Coupled and Miniaturized Ultrasound Transducer System for Long-Term, Wearable Neuromodulation

Tang, K. W. K.; Jeong, J.; Ju-Chun, H.; Yao, M.; Ding, H.; Wang, W.; Liu, X.; Pyatnitskiy, I.; He, W.; Moscoso-Barrera, W. D.; Lozano, A. R.; Artman, B.; Huh, H.; Wilson, P. S.; Wang, H.

10.1101/2024.07.17.603650 — bioengineering — Posted on 2024-07-22

1858 Development of 3-in-1 nanotherapeutic strategies for ovarian cancer

Durocher, E.; McGrath, S.; Gahunia, E.; Matsuura, N.; Gadde, S.

10.1101/2024.07.17.604002 — bioengineering — Posted on 2024-07-22

1859 De Novo Design of Peptide Binders to Conformationally Diverse Targets with Contrastive Language Modeling

Bhat, S.; Palepu, K.; Hong, L.; Mao, J.; Ye, T.; Iyer, R.; Zhao, L.; Chen, T.; Vincoff, S.; Watson, R.; Wang, T.; Srijay, D.; Kavirayuni, V. S.; Kholina, K.; Goel, S.; Vure, P.; Desphande, A. H.; Soderling, S.; DeLisa, M.; Chatterjee, P.

10.1101/2023.06.26.546591 — bioengineering — Posted on 2024-07-22

1860 Genetic basis of state-dependent courtship sounds in inbred mice

Na, S.; Ryoo, J.; Ko, C. B.; Park, S.; Kim, D.

10.1101/2024.07.22.604528 — animal behavior and cognition — Posted on 2024-07-22

1861 Instantaneous Flow Analysis of Contractile Cytoskeletal Structures Affected by the Dysregulation of Kinesin and Tropomyosin Motors

Matov, A.

10.1101/2024.06.28.601275 — cell biology — Posted on 2024-07-22

1862 A neurofunctional signature of affective arousal generalizes across valence domains and distinguishes subjective experience from autonomic reactivity

Zhang, R.; Gan, X.; Xu, T.; Yu, F.; Wang, L.; Song, X.; Jiao, G.; Liu, X.; Zhou, F.; Becker, B.

10.1101/2024.07.17.604003 — neuroscience — Posted on 2024-07-22

1863 No evidence that individual alpha frequency (IAF) represents a mechanism underlying motion-position illusions

Cottier, T. V.; Turner, W.; Chae, V. J.; Holcombe, A. O.; Hogendoorn, H.

10.1101/2024.07.17.603862 — neuroscience — Posted on 2024-07-22

1864 The N-degron pathway governs autophagy to promote thermotolerance in Arabidopsis

Kim, S. H.; Park, J. S.; Lee, M.-H.; Seo, J.; Kim, J.; Yang, W. S.; Park, J.; Yoo, K.; Choi, J.; Seo, J.-B.; Song, H. K.; Park, O. K.

10.1101/2024.07.17.604022 — plant biology — Posted on 2024-07-22

1865 Multiomics-based assessment of the impact of airflow on diverse plant callus cultures

Kim, J.-S.; Sato, M.; Kojima, M.; Asrori, M. I.; Uehara-Yamaguchi, Y.; Takebayashi, Y.; Do, T. N.; Do, T. Y.; Thi, K. O. N.; Sakakibara, H.; Mochida, K.; Ogita, S.; Hirai, M. Y.

10.1101/2024.07.17.604000 — plant biology — Posted on 2024-07-22

1866 Thermal cycling hyperthermia sensitizes non-small cell lung cancer A549 cells to EGFR-tyrosine kinase inhibitor Erlotinib

Lin, G.-B.; Chen, W.-T.; Kuo, Y.-Y.; Liu, H.-H.; Chen, Y.-M.; Leu, S.-J.; Chao, C.-Y.

10.1101/2022.05.03.490542 — cancer biology — Posted on 2024-07-22

1867 iPAR: a new reporter for eukaryotic cytoplasmic protein aggregation

Lecinski, S.; Howard, J. A. L.; MacDonald, C.; Leake, M. C.

10.1101/2024.01.29.577793 — biophysics — Posted on 2024-07-22

1868 Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation

Asai, R.; Sinha, S.; Prakash, V. N.; Mikawa, T.

10.1101/2024.04.21.590437 — biophysics — Posted on 2024-07-22

1869 Early Steps of Protein Disaggregation by Hsp70 Chaperone and Class B J-Domain Proteins are Shaped by Hsp110

Sztangierska, W.; Wyszkowski, H.; Pokornowska, M.; Kochanowicz, K.; Rychlowski, M.; Liberek, K.; Klosowska, A.

10.1101/2023.10.31.564973 — biochemistry — Posted on 2024-07-22

1870 BETA-HYDROXYBUTYRATE COUNTERACTS THE DELETERIOUS EFFECTS OF A SATURATED HIGH-FAT DIET ON SYNAPTIC AMPA RECEPTORS AND COGNITIVE PERFORMANCE

Rojas, R.; Grinan-Ferre, C.; Castellanos, A.; Griego, E.; Martinez, M.; Navarro-Lopez, J. d. D.; Jimenez-Diaz, L.; Rodriguez-Alvarez, J.; Soto del Cerro, D.; Castillo, P. E.; Pallas, M.; Fado, R.; Casals, N.

10.1101/2024.01.23.576931 — neuroscience — Posted on 2024-07-22

1871 Sequential replacement of PSD95 subunits in postsynaptic supercomplexes is slowest in the cortex.

Morris, K.; Bulovaite, E.; Kaizuka, T.; Schnorrenberg, S.; Adams, C.; Komiyama, N.; Mendive-Tapia, L.; Grant, S. G. N.; Horrocks, M. H.

10.1101/2023.07.13.548866 — neuroscience — Posted on 2024-07-22

1872 The value of livestock abortion surveillance in Tanzania: identifying disease priorities and informing interventions

Lankester, F.; Kibona, T. J.; Allan, K. J.; de Glanville, W.; Buza, J. J.; Katzer, F.; Halliday, J. E.; Mmbaga, B. T.; Wheelhouse, N.; Innes, E. A.; Thomas, K.; Nyasebwa, O. M.; Swai, E.; Claxton, J. R.; Cleaveland, S.

10.1101/2024.01.07.574517 — zoology — Posted on 2024-07-22

1873 GLP-1 receptor agonist exenatide uncouples food intake from hedonic and anticipatory regulation in non-human primates: Insights from an operant meal schedule paradigm

Knakker, B.; Inkeller, J.; Kovacs, P.; Lendvai, B.; Hernadi, I.

10.1101/2024.03.18.585513 — pharmacology and toxicology — Posted on 2024-07-22

1874 Evolution of the CRISPR-Cas9 defence system in Mycoplasma gallisepticum following colonization of a novel bird host

Ipoutcha, T.; Tsarmpopoulos, I.; Gourgues, G.; Baby, V.; Dubos, P.; Hill, G. E.; Arfi, Y.; Lartigue, C.; Thebault, P.; Bonneaud, C.; Sirand-Pugnet, P.

10.1101/2023.03.14.532377 — microbiology — Posted on 2024-07-22

1875 Hearing and cognitive decline in aging differentially impact neural tracking of context-supported versus random speech across linguistic timescales

Bolt, E.; Kliestenec, K.; Giroud, N.

10.1101/2024.07.16.603693 — neuroscience — Posted on 2024-07-22

1876 Reduced discrimination between signals of danger and safety but not overgeneralization is linked to exposure to childhood adversity in healthy adults

Klingelhoefer-Jens, M.; Hutterer, K.; Schiele, M. A.; Leehr, E. J.; Schuemann, D.; Rosenkranz, K.; Boehnlein, J.; Repple, J.; Deckert, J.; Domschke, K.; Dannlowski, U.; Lueken, U.; Reif, A.; Romanos, M.; Zwanzger, P.; Pauli, P.; Gamer, M.; Lonsdorf, T. B.

10.1101/2023.09.26.559474 — neuroscience — Posted on 2024-07-22

1877 Multi-way modelling of oral microbial dynamics and host-microbiome interactions during induced gingivitis

van der Ploeg, G. R.; Brandt, B.; Keijser, B.; van der Veen, M.; Volgenant, C.; Zaura, E.; Smilde, A.; Westerhuis, J.; Heintz-Buschart, A.

10.1101/2024.03.18.585469 — systems biology — Posted on 2024-07-22

1878 Spatial Transcriptomics in Bone Mechanomics: Exploring the Mechanoregulation of Fracture Healing in the Era of Spatial Omics.

Mathavan, N.; Singh, A.; Correia Marques, F.; Günther, D.; Kuhn, G.; Wehrle, E.; Müller, R.

10.1101/2024.04.18.590091 — physiology — Posted on 2024-07-22

1879 Has AlphaFold 3 reached its success for RNAs?

Bernard, C.; Postic, G.; Ghannay, S.; Tahi, F.

10.1101/2024.06.13.598780 — bioinformatics — Posted on 2024-07-22

1880 ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance

Fukunaka, A.; Tanaka, G.; Kimura, T.; Hengphasatporn, K.; Saito, D.; Shigeta, M.; Shibata, H.; Ichinose, T.; Abe, I.; Shimura, M.; Sato, T.; Nakagawa, Y.; Horii, T.; Hatada, I.; Kajimura, S.; Kiyonari, H.; Sakurai, H.; Shigeta, Y.; Watada, H.; Fukada, T.; Fujitani, Y.

10.1101/2024.07.03.601606 — cell biology — Posted on 2024-07-22

1881 Hierarchical structural organization in bioinspired peptide coacervate microdroplets

Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q. M.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.

10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-22

1882 Cohesin-mediated 3D contacts tune enhancer-promoter regulation

Guckelberger, P.; Doughty, B. R.; Munson, G.; Rao, S. S. P.; Tan, Y.; Cai, X. S.; Fulco, C. P.; Nasser, J.; Mualim, K. S.; Bergman, D. T.; Ray, J.; Jagoda, E.; Munger, C. J.; Gschwind, A. R.; Sheth, M. U.; Tan, A. S.; Pulido, S. G.; Mitra, N.; Weisz, D.; Shamim, M. S.; Durand, N. C.; Mahajan, R.; Khan, R.; Steinmetz, L. M.; Kanemaki, M. T.; Lander, E. S.; Meissner, A.; Aiden, E. L.; Engreitz, J. M.

10.1101/2024.07.12.603288 — molecular biology — Posted on 2024-07-22

1883 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria

Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Li, J.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.

10.1101/2024.02.24.581832 — microbiology — Posted on 2024-07-22

1884 Proteomic evidence of depression-associated astrocytic dysfunction in the human male olfactory bulb

Rahimian, R.; Perlman, K.; Fakhfouri, G.; Mpai, R.; Richard, V. R.; Hercher, C.; Penney, L.; Davoli, M. A.; Nagy, C.; Zahedi, R. P.; Borchers, C. H.; Giros, B.; Turecki, G.; Mechawar, N.

10.1101/2023.10.29.564604 — neuroscience — Posted on 2024-07-22

1885 Inference of gene regulatory networks for overcoming low performance in real-world data

Hiki, Y.; Tokuoka, Y.; Yamada, T. G.; Funahashi, A.

10.1101/2024.07.16.603684 — systems biology — Posted on 2024-07-22

1886 Automated detection of Bornean white-bearded gibbon (Hylobates albibarbis) vocalisations using an open-source framework for deep learning

Owens, A. F.; Hockings, K. J.; Imron, M. A.; Madhusudhana, S.; Mariaty, ; Setia, T. M.; Sharma, M. D.; Soebagio, S. M.; Van Veen, F. J. F.; Erb, W. M.

10.1101/2024.04.15.589517 — ecology — Posted on 2024-07-21

1887 Super-enhancer-driven CACNA2D2 is an EWSR1::WT1 signature gene encoding a diagnostic marker for desmoplastic small round cell tumor (DSRCT)

Geyer, F. H.; Ritter, A.; Kinn-Gurzo, S.; Faehling, T.; Li, J.; Jarosch, A.; Ngo, C.; Vinca, E.; Aljakouch, K.; Orynbek, A.; Ohmura, S.; Kirchner, T.; Imle, R.; Romero-Perez, L.; Bertram, S.; de Alava, E.; Postel-Vilnay, S.; Banito, A.; Sill, M.; Versleijen-Jonkers, Y. M. H.; Mayer, B. F. B.; Ebinger, M.; Sparber-Sauer, M.; Stegmaier, S.; Baumhoer, D.; Hartmann, W.; Krijgsveld, J.; Horst, D.; Delattre, O.; Grohar, P. J.; Gruenewald, T. G. P.; Cidre-Aranaz, F.

10.1101/2024.07.17.603708 — cancer biology — Posted on 2024-07-21

1888 The inhibition of three distinct signaling pathways eliminates the oncogenic Tribbles homolog 2 from melanoma cells

Mayoral-Varo, V.; Orea-Soufi, A.; Jimenez, L.; Santos, B.; Serrao, G.; Jociles, M.; Obeso, S.; Ferreira, B.; Link, W.

10.1101/2024.07.17.603886 — cancer biology — Posted on 2024-07-21

1889 Tubules, rods and spirals: diverse modes of SepF-FtsZ assembling

Chaudhuri, B.; Choudhury, J.

10.1101/2024.07.18.604210 — biophysics — Posted on 2024-07-21

1890 DrugDiff - small molecule diffusion model with flexible guidance towards molecular properties

Oestreich, M.; Merdivan, E.; Lee, M.; Schultze, J. L.; Piraud, M.; Becker, M.

10.1101/2024.07.17.603873 — bioinformatics — Posted on 2024-07-21

1891 Deep Profiling of Plasma Proteoforms with Engineered Nanoparticles for Top-down Proteomics

Huang, C.-F.; Hollas, M. A.; Sanchez, A.; Bhattacharya, M.; Ho, G.; Sundaresan, A.; Caldwell, M. A.; Zhao, X.; Benz, R.; Siddiqui, A.; Kelleher, N. L.

10.1101/2024.07.20.604425 — biochemistry — Posted on 2024-07-21

1892 AQuaRef: Machine learning accelerated quantum refinement of protein structures

Zubatyuk, R.; Biczysko, M.; Ranasinghe, K.; Moriarty, N. W.; Gokcan, H.; Kruse, H.; Poon, B. K.; Adams, P. D.; Waller, M. P.; Roitberg, A. E.; Isayev, O.; Afonine, P. V.

10.1101/2024.07.21.604493 — biochemistry — Posted on 2024-07-21

1893 Identification of novel human 15-lipoxygenase-2 (h15-LOX-2) inhibitors using a virtual screening approach

Viviani, L. G.; Iijima, T. S.; Piccirillo, E.; de Rezende, L.; Alegria, T. G. P.; Netto, L. E. S.; do Amaral, A. T.; Miyamoto, S.

10.1101/2024.07.21.604444 — biochemistry — Posted on 2024-07-21

1894 Multi-Response Phylogenetic Mixed Models: Concepts andApplication

Halliwell, B.; Holland, B. R.; Yates, L. A.

10.1101/2022.12.13.520338 — evolutionary biology — Posted on 2024-07-21

1895 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep

Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.

10.1101/2023.07.21.550073 — ecology — Posted on 2024-07-21

1896 BCAS2 promotes primitive hematopoiesis by sequestering β-catenin within the nucleus

Ning, G.; Lin, Y.; Ma, H.; Zhang, J.; Yang, L.; Liu, Z.; Li, L.; He, X.; Wang, Q.

10.1101/2024.07.17.603892 — developmental biology — Posted on 2024-07-21

1897 Pharmacologically inducing regenerative cardiac cells by small molecule drugs

Zhou, W.; He, K.; Wang, C.; Wang, P.; Wang, D.; Wang, B.; Geng, H.; Lian, H.; Ma, T.; Nie, Y.; Ding, S.

10.1101/2023.10.24.563872 — cell biology — Posted on 2024-07-21

1898 Mutational landscape and molecular bases of echinocandin resistance

Durand, R.; Torbey, A. G.; Giguere, M.; Pageau, A.; Dube, A. K.; Lagüe, P.; Landry, C. R.

10.1101/2024.07.21.604487 — molecular biology — Posted on 2024-07-21

1899 Discovery and Engineering of Retrons for Precise GenomeEditing

Buffington, J. D.; Kuo, H.-C.; Hu, K.; Chang, Y.-C.; Javanmardi, K.; Voigt, B.; Li, Y.-R.; Little, M. E.; Devanathan, S. K.; Xhemalce, B.; GRAY, R.; Finkelstein, I. J.

10.1101/2024.07.21.604473 — molecular biology — Posted on 2024-07-21

1900 RNaseH-based ribodepletion of total planarian RNA improves detection of longer and non-polyadenylated transcripts

Barai, P.; Biswas, S.; Verma, P.; Duncan, E.

10.1101/2024.07.20.604429 — molecular biology — Posted on 2024-07-21

1901 Mathematical modeling using box-behnken response surface design for optimal DNA yield with variable parameters of time, temperature, and proteinase K concentration

Afzal, F.; Zia, S.; Saif, R.

10.1101/2024.07.21.604461 — molecular biology — Posted on 2024-07-21

1902 Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier-Transform Infrared (FT-IR) Spectroscopy

Rodriguez-Temporal, D.; Sanchez-Cueto, M.; Buenestado-Serrano, S.; Blazquez-Sanchez, M.; Cercenado, E.; Gutierrez-Pareja, M.; Molero-Salinas, A.; Lopez-Camacho, E.; Munoz, P.; Garcia de Viedma, D.; Perez-Lago, L.; Rodriguez-Sanchez, B.

10.1101/2024.07.18.604080 — microbiology — Posted on 2024-07-21

1903 Still Not Sterile: Chlorhexidine gluconate treatment does not completely reduce skin microbial bioburden and promotes pathogen overabundance in patients undergoing elective surgeries.

Townsend, E. C.; Xu, K.; De La Cruz, K.; Huang, L.; Sandstrom, S.; Arend, D.; Gromek, O.; Scarborough, J. E.; Huttenlocher, A. C.; Gibson, A.; Kalan, L.

10.1101/2024.07.20.602341 — microbiology — Posted on 2024-07-21

1904 Ablation of B cell-derived IL-10 increases tuberculosis resistance

Hertz, D.; Marwitz, S.; Eggers, L.; von Borstel, L.; Harikumar Parvathy, G.; Behrends, J.; Jonigk, D. D.; Manz, R.; Goldmann, T.; Schneider, B. E.

10.1101/2024.07.17.603865 — immunology — Posted on 2024-07-21

1905 A simple statistical framework for small sample studies

Schwarzkopf, D. S.; Huang, Z.

10.1101/2023.09.19.558509 — neuroscience — Posted on 2024-07-21

1906 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance

Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.

10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-21

1907 Subthalamic nucleus activity dynamics preceding clinical manifestations in a progressive Parkinson's disease model.

Bertrand, M.; Chabardes, S.; De Leiris, N.; Riboulet, G.; Baudin, B.; Bastin, J.; Piallat, B.

10.1101/2024.01.22.576571 — neuroscience — Posted on 2024-07-21

1908 Linking Gba1 E326K mutation to microglia activation and mild age-dependent dopaminergic Neurodegeneration

Kweon, S. H.; Ryu, H. G.; Park, H.; Lee, S.; Kim, N.; Kwon, S.-H.; Ma, S.; Kim, S.; Ko, H. S.

10.1101/2023.09.14.557673 — neuroscience — Posted on 2024-07-21

1909 Multimodal screen reveals noise regulatory proteins

Garcia-Blay, O.; Hu, X.; Wassermann, C. L.; van Bokhoven, T.; Struijs, F. M. B.; Hansen, M. M. K.

10.1101/2024.07.17.603871 — systems biology — Posted on 2024-07-21

1910 Fine Tuning Genetic Circuits via Host Context and RBS Modulation

Chan, D. T. C.; Winter, L.; Bjerg, J.; Krsmanovic, S.; Baldwin, G. S.; Bernstein, H. C.

10.1101/2024.07.20.604438 — synthetic biology — Posted on 2024-07-21

1911 C-terminally encoded peptides promoting root symbiotic nodulation in legume plants also promote the root arbuscular mycorrhizal symbiotic interaction

Pedinotti, L.; Teyssendier de la Serve, J.; Roudaire, T.; San Clemente, H.; Aguilar, M.; Kohlen, W.; Frugier, F.; Frei dit Frey, N.

10.1101/2024.07.17.603861 — plant biology — Posted on 2024-07-21

1912 MONOPTEROS isoform MP11ir role during somatic embryogenesis in Arabidopsis thaliana

Wojcikowska, B.; Belaidi, S.; Mironova, V.; Robert, H. S.

10.1101/2024.07.17.603838 — plant biology — Posted on 2024-07-21

1913 DOG1 prevents AFPs activation by AHG1 to control dormancy separately from ABA core signaling

Krueger, T.; Brandt, D.; Sodenkamp, J.; Gasper, M.; Branchat, M.; Ahloumessou, F.; Gehring, E.; Drotleff, J.; Bell, C.; Kramer, K.; Eirich, J.; Soppe, W. J. J.; Finkemeier, I.; Nee, G.

10.1101/2024.07.17.603870 — plant biology — Posted on 2024-07-21

1914 Molecular events accompanying aggregation-induced energy quenching in Fucoxanthin-Chlorophyll Proteins

Alexandre, M. M.; Kruger, T. P.; Pascal, A. A.; Veremeienko, V.; Llansola-Portoles, M.; Gundermann, K.; van Grondelle, R.; Buechel, C.; Robert, B.

10.1101/2024.03.20.585890 — biophysics — Posted on 2024-07-21

1915 PINDER: The protein interaction dataset and evaluation resource

Kovtun, D.; Akdel, M.; Goncearenco, A.; Zhou, G.; Holt, G.; Baugher, D.; Lin, D.; Adeshina, Y.; Castiglione, T.; Wang, X.; Marquet, C.; McPartlon, M.; Geffner, T.; Corso, G.; Stark, H.; Carpenter, Z.; Kucukbenli, E.; Bronstein, M.; Naef, L.

10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-21

1916 Comparative single-cell transcriptomic analysis reveals putative differentiation drivers and potential origin of vertebrate retina

Zeng, X.; Gyoja, F.; Cui, Y.; Loza, M.; Kusakabe, T. G.; Nakai, K.

10.1101/2023.12.03.569795 — bioinformatics — Posted on 2024-07-21

1917 Megakaryocyte maturation involves activation of the adaptive unfolded protein response

Faiz, M.; Kalev-Zylinska, M. L.; Dunstan-Harrison, C.; Singleton, D. C.; Hay, M. P.; Ledgerwood, E. C.

10.1101/2023.07.26.550730 — cell biology — Posted on 2024-07-21

1918 Voluntary adolescent alcohol exposure does not robustly increase adulthood consumption of alcohol in multiple mouse and rat models

Sicher, A. R.; Liss, A.; Vozella, V.; Marsland, P.; Seemiller, L. R.; Springer, M.; Starnes, W. D.; Griffith, K. R.; Smith, G. C.; Astefanous, A.; Deak, T.; Roberto, M.; Varodayan, F. P.; Crowley, N. A.

10.1101/2024.04.30.591674 — neuroscience — Posted on 2024-07-21

1919 Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus

Lanzetta, O.; Bilio, M.; Liebig, J.; Jechow, K.; Ten, F. W.; Ferrentino, R.; Aurigemma, I.; Illingworth, E.; Conrad, C.; Lukassen, S.; Angelini, C.; Baldini, A.

10.1101/2024.07.16.603669 — developmental biology — Posted on 2024-07-21

1920 Striatal endocannabinoid-long-term potentiation mediates one-shot learning

Piette, C.; Hubert, A.; Perez, S.; Berry, H.; Touboul, J. D.; Venance, L.

10.1101/2024.07.10.602953 — neuroscience — Posted on 2024-07-21

1921 Bilateral cellular flows display asymmetry prior to left-right organizer formation in amniote gastrulation

Asai, R.; Sinha, S.; Prakash, V. N.; Mikawa, T.

10.1101/2024.04.21.590437 — biophysics — Posted on 2024-07-21

1922 High-density sampling reveals volume growth in human tumours

Angaji, A.; Owusu, M.; Velling, C.; Dick, N.; Weghorn, D.; Berg, J.

10.1101/2023.12.10.570995 — cancer biology — Posted on 2024-07-21

1923 SciMind: A Multimodal Mixture-of-Experts Model for Advancing Pharmaceutical Sciences

Xiong, Z.; Fang, X.; Chu, H.; Wan, X.; Liu, L.; Xiang, W.; Li, Y.; Zheng, M.

10.1101/2024.07.16.603812 — bioinformatics — Posted on 2024-07-21

1924 Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.

Herrmannova, A.; Jelinek, J.; Pospisilova, K.; Kerenyi, F.; Vomastek, T.; Watt, K.; Brabek, J.; Mohammad, M. P.; Wagner, S.; Topisirovic, I.; Valasek, L. S.

10.1101/2023.06.29.547003 — molecular biology — Posted on 2024-07-21

1925 Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier-Transform Infrared (FT-IR) Spectroscopy

10.1101/2024.07.18.604080 — microbiology — Posted on 2024-07-21

1926 Multi-level processing of emotions in life motion signals revealed through pupil responses

Yuan, T.; Wang, L.; Jiang, Y.

10.1101/2023.07.18.549471 — neuroscience — Posted on 2024-07-21

1927 Foothold selection during locomotion in uneven terrain: Results from the integration of eye tracking, motion capture, and photogrammetry

Muller, K. S.; Panfili, D.; Shields, S. M.; Matthis, J.; Bonnen, K.; Hayhoe, M.

10.1101/2023.08.18.553818 — neuroscience — Posted on 2024-07-21

1928 FORWARD: A Learning Framework for Logical Network Perturbations to Prioritize Targets for Drug Development

Sinha, S.; McLaren, E. G.; Mullick, M.; Singh, S.; Boland, B. S.; Ghosh, P.

10.1101/2024.07.16.602603 — bioinformatics — Posted on 2024-07-21

1929 MALAT1 expression indicates cell quality in single-cell RNA sequencing data

Clarke, Z. A.; Bader, G. D.

10.1101/2024.07.14.603469 — bioinformatics — Posted on 2024-07-21

1930 SAMA: a contig assembler with correctness guarantee

Salmela, L.

10.1101/2024.07.10.602853 — bioinformatics — Posted on 2024-07-21

1931 Pyramidal neurons proportionately alter the identity and survival of specific cortical interneuron subtypes

Wu, S. J.; Dai, M.; Yang, S.-P.; McCann, C.; Qiu, Y.; Marrero, G. J.; Stogsdill, J. A.; Di Bella, D. J.; Xu, Q.; Farhi, S. L.; Macosko, E. Z.; Chen, F.; Fishell, G.

10.1101/2024.07.20.604399 — neuroscience — Posted on 2024-07-21

1932 Decoding contextual influences on auditory perception from primary auditory cortex

Englitz, B.; Akram, S.; Elhilali, M.; Shamma, S.

10.1101/2023.12.24.573229 — neuroscience — Posted on 2024-07-21

1933 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures

Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.

10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-07-21

1934 Embryo movement is required for limb tendon maturation

Rolfe, R. A.; Talak Basturkmen, E.; Sliney, L.; Hayden, G.; Dunne, N.; Buckley, N.; McCarthy, H.; Szczesny, S.; Murphy, P.

10.1101/2024.07.18.604105 — developmental biology — Posted on 2024-07-21

1935 Reward history guides attentional selection in whisker somatosensory (S1) cortex

Ramamurthy, D.; Rodriguez, L.; Cen, C.; Li, S.; Chen, A.; Feldman, D. E.

10.1101/2024.07.17.603927 — neuroscience — Posted on 2024-07-21

1936 Spatial constraints and cell surface molecule depletion structure a randomly connected learning circuit

Thornton-Kolbe, E. M.; Ahmed, M.; Gordon, F. R.; Sieriebriennikov, B.; Williams, D. L.; Kurmangaliyev, Y. Z.; Clowney, E. J.

10.1101/2024.07.17.603956 — neuroscience — Posted on 2024-07-21

1937 Hierarchical Bayesian modeling of multi-region brain cell count data

Dimmock, S.; Exley, B. M. S.; Moore, G.; Menage, L.; Delogu, A.; Schultz, S. R.; Warburton, E. C.; Houghton, C. J.; O'Donnell, C.

10.1101/2024.07.20.603979 — neuroscience — Posted on 2024-07-21

1938 Self-avoidance dominates the selection of hippocampal replay

Mallory, C. S.; Widloski, J.; Foster, D. J.

10.1101/2024.07.18.604185 — neuroscience — Posted on 2024-07-21

1939 DdmDE eliminates plasmid invasion by DNA-guided DNA targeting

Yang, X.; Shen, Z.; Wang, C.; Nakanishi, K.; Fu, T.

10.1101/2024.07.20.604412 — biophysics — Posted on 2024-07-20

1940 Structural Dynamics of the Ubiquitin Specific Protease USP30 in Complex with a Cyanopyrrolidine-Containing Covalent Inhibitor

O'Brien, D. P.; Jones, H. B.; Shi, Y.; Guenther, F.; Vendrell, I.; Viner, R.; Brennan, P. E.; Mead, E.; Zarganis-Tzitzikas, T.; Davis, J. B.; Pinto-Fernandez, A.; England, K. S.; Murphy, E. J.; Turnbull, A. P.; Kessler, B. M.

10.1101/2024.07.20.604388 — biochemistry — Posted on 2024-07-20

1941 Integrated proteasomal and lysosomal activity shape mTOR-regulated proteome remodeling

Cui, D. S.; Webster, S. M.; Davis, J. H.

10.1101/2024.07.20.603815 — biochemistry — Posted on 2024-07-20

1942 Lactate-carried Mitochondrial Energy Overflow

Rauseo, D.; Contreras-Baeza, Y.; Faurand, H.; Carcamo, N.; Suarez, R.; von Faber-Castell, A.; Silva, F.; Mora-Gonzalez, V.; Wyss, M. T.; Baeza-Lehnert, F.; Ruminot, I.; Alvarez-Navarro, C.; San Martin, A.; Weber, B.; Sandoval, P. Y.; Barros, L. F.

10.1101/2024.07.19.604361 — biochemistry — Posted on 2024-07-20

1943 Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron

Zielinski, K. A.; Dolamore, C.; Dalton, K. M.; Smith, N.; Termini, J.; Henning, R.; Srajer, V.; Hekstra, D. R.; Pollack, L.; Wilson, M. A.

10.1101/2024.07.19.604369 — biochemistry — Posted on 2024-07-20

1944 ALS molecular subtypes are a combination of cellular, genetic, and pathological features learned by deep multiomics classifiers

ONeill, K.; Shaw, R.; Bolger, I.; NYGC ALS Consortium, ; Tam, O. H.; Phatnani, H.; Gale Hammell, M.

10.1101/2024.07.19.603731 — genomics — Posted on 2024-07-20

1945 Single laboratory evaluation of the (Q20+) nanopore sequencing kit for bacterial outbreak investigations

Hoffmann, M.; Jang, J. H.; Tallent, S. M.; Gonzalez-Escalona, N.

10.1101/2024.07.17.603985 — genomics — Posted on 2024-07-20

1946 Manganese transporter SLC30A10 and iron transporters SLC40A1 and SLC11A2 impact dietary manganese absorption

Prajapati, M.; Zhang, J. Z.; Chong, G. S.; Chiu, L.; Mercadante, C. J.; Kowalski, H. L.; Antipova, O.; Lai, B.; Ralle, M.; Jackson, B. P.; Punshon, T.; Guo, S.; Aghajan, M.; Bartnikas, T. B.

10.1101/2024.07.17.603814 — genetics — Posted on 2024-07-20

1947 Two dimensional sequence alignment shows that replication slippage may generate a significant proportion of all transversion substitutions.

Erives, A. J.

10.1101/2024.07.17.603925 — genetics — Posted on 2024-07-20

1948 Expansion of the MutS gene family in plants

Sloan, D. B.; Broz, A. K.; Kuster, S. A.; Muthye, V.; Penafiel-Ayala, A.; Marron, J. R.; Lavrov, D. V.; Brieba, L. G.

10.1101/2024.07.17.603841 — evolutionary biology — Posted on 2024-07-20

1949 A facile chemical strategy to synthesize precise AAV-protein conjugates for targeted gene delivery

Pham, Q.; Glicksman, J.; Shahraeini, S. S.; Han, B.; Jewel, D.; Loynd, C.; Singha Roy, S. J.; Chatterjee, A.

10.1101/2024.07.20.604406 — synthetic biology — Posted on 2024-07-20

1950 Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction

Sun, L.; Guo, X.; Yu, M.; Wang, X.-F.; Ren, H.; Wang, X.

10.1101/2024.07.19.604247 — microbiology — Posted on 2024-07-20

1951 A scalable genetic tool for the functional analysis of the signal recognition particle.

Long, L. F.; Biskunda, S.; Yang, M.; Wu, G. C.; Simas, C. F.; Bruner, S. D.; Denard, C. A.

10.1101/2024.07.20.602779 — synthetic biology — Posted on 2024-07-20

1952 Structural basis of long-range transcription-translation coupling

Wang, C.; Molodtsov, V.; Kaelber, J.; Blaha, G.; Ebright, R. H.

10.1101/2024.07.20.604413 — molecular biology — Posted on 2024-07-20

1953 N6-methyladenosine in DNA promotes genome stability

Conti, B.; Novikov, L.; Tong, D.; Xiang, Q.; Nguyen, C.; Vigil, S.; McLellan, T. J.; De La Cruz, N.; Veettil, R. T.; Pradhan, P.; Sahasrabudhe, P.; Arroyo, J. D.; Shang, L.; Sabari, B. R.; Shields, D. J.; Oppikofer, M.

10.1101/2024.07.20.604187 — molecular biology — Posted on 2024-07-20

1954 Oxygen Microenvironments in E. coli Biofilm Nutrient Transport Channels: Insights from Complementary Sensing Approaches

Bottura, B.; McConnell, G.; Florek, L. C.; Smiley, M. K.; Martin, R.; Eana, A.; Dayton, H. T.; Eckartt, K. N.; Price-Whelan, A.; Hoskisson, P. A.; Dietrich, L. E. P.; Rooney, L. M.

10.1101/2024.07.20.603676 — microbiology — Posted on 2024-07-20

1955 Meta-omics reveals role of photosynthesis in Microbially Induced Carbonate Precipitation at a CO2-rich Geyser

Violette, M.; Hyland, E.; Burgener, L.; Ghosh, A.; Montoya, B.; Kleiner, M.

10.1101/2024.07.20.604422 — microbiology — Posted on 2024-07-20

1956 Cryptosporidium Oocyst Wall Proteins are true oocyst wall proteins, with COWP8 functioning to hold the inner and outer layers of the oocyst wall together

Bacchetti, R.; Stevens, S.; Lemgruber, L.; Oliva, M. A. G.; Sands, E. M.; Alexandrou, K.; Tinti, M.; Robinson, L.; Hanna, J. C.; Seizova, S.; Goddard, P.; Vassalli, M.; Pawlowic, M. C.

10.1101/2024.07.20.604394 — microbiology — Posted on 2024-07-20

1957 The deletion of aldehyde:ferredoxin oxidoreductase-encoding genes in Clostridium ljungdahlii results in changes in the product spectrum with various carbon sources

Baur, S. T.; Schulz, S.; McCluskey, J. B.; Velazquez Gomez, J. A.; Angenent, L. T.; Molitor, B.

10.1101/2024.07.20.604392 — microbiology — Posted on 2024-07-20

1958 Clonal heterogeneity and antigenic stimulation shape persistence of the latent reservoir of HIV

Garcia Noceda, M.; Barton, J. P.

10.1101/2024.07.19.604385 — immunology — Posted on 2024-07-20

1959 Identification and characterization of thiamine analogues with antiplasmodial activity

Fathoni, I.; Ho, T. C.; Chan, A. H.; Leeper, F. J.; Matuschewski, K.; Saliba, K. J.

10.1101/2024.07.18.604204 — pharmacology and toxicology — Posted on 2024-07-20

1960 CONDENSATES OF SYNAPTIC VESICLES AND SYNAPSIN ARE MOLECULAR BEACONS FOR ACTIN SEQUESTERING AND POLYMERIZATION

Chhabra, A.; Hoffmann, C.; Korobeinikov, A.; Rentsch, J.; Kokwaro, L.; Gnidovec, L.; Cristina, R.-V.; Johnson, E.; Wallace, J.; Rankovic, B.; Perego, E.; Koester, S.; Rizzoli, S.; Ewers, H.; Morgan, J.; Milovanovic, D.

10.1101/2024.07.19.604346 — cell biology — Posted on 2024-07-20

1961 Trichoderma afroharzianum T22 induces rhizobia and flavonoid through systemic signaling to combat Fe deficiency in garden pea

Thapa, A.; Hasan, M. R.; Kabir, A. H.

10.1101/2024.07.11.603139 — plant biology — Posted on 2024-07-20

1962 Compressive Pangenomics Using Mutation-Annotated Networks

Walia, S.; Motwani, H.; Smith, K.; Corbett-Detig, R.; Turakhia, Y.

10.1101/2024.07.02.601807 — bioinformatics — Posted on 2024-07-20

1963 Doublecortin restricts neuronal branching by regulating tubulin polyglutamylation

Sebastien, M.; Paquette, A. L.; Prowse, E. N. P.; Hendricks, A. G.; Brouhard, G. J.

10.1101/2023.06.02.543327 — cell biology — Posted on 2024-07-20

1964 Salmonella injectisome penetration of macrophages triggers rapid translation of transcription factors and protection against cell death

Wood, G.; Johnson, R.; Powell, J.; Bryant, O.; Lastovka, F.; Brember, M.; Tourlomousis, P.; Carr, J.; Bryant, C.; Chung, B. Y.

10.1101/2023.07.21.550113 — molecular biology — Posted on 2024-07-20

1965 Predictive Modeling of Evoked Intracranial EEG Response to Medial Temporal Lobe Stimulation in Patients with Epilepsy

Acharya, G.; Davis, K. A.; Nozari, E.

10.1101/2023.08.07.552297 — neuroscience — Posted on 2024-07-20

1966 PINDER: The protein interaction dataset and evaluation resource

10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-20

1967 Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study

Khoza, S.; George, J. A.; Naicker, P.; Stoychev, S. H.; Fabian, J.; Govender, I. S.

10.1101/2024.07.16.603438 — biochemistry — Posted on 2024-07-20

1968 Stem cell transcriptional profiles from mouse subspecies reveal cis-regulatory evolution at translation genes

Simon, N. M.; Kim, Y.; Bautista, D. M.; Dutton, J. R.; Brem, R. B.

10.1101/2023.07.18.549406 — evolutionary biology — Posted on 2024-07-20

1969 Ecological factors alter how spatial overlap predicts viral infection dynamics in wild rodent populations

Mistrick, J.; Veitch, J. S.; Wearing, K. E.; Kitchen, S. M.; Clague, S.; Du, S.; Michalska-Smith, M.; Newman, B. C.; Sironen, T.; Cressler, C. E.; Hall, R. J.; Budischak, S. A.; Forbes, K. M.; Craft, M. E.

10.1101/2024.06.19.599763 — ecology — Posted on 2024-07-20

1970 Plasmodium falciparum disruption of pericyte angiopoietin-1 secretion contributes to barrier breakdown in a 3D brain microvessel model

Long, R. K. M.; Korbmacher, F.; Ronchi, P.; Fleckenstein, H.; Schorb, M.; Mirza, W.; Mallorqui, M.; Aguilar, R.; Moncunill, G.; Schwab, Y.; Bernabeu, M.

10.1101/2024.03.29.587334 — microbiology — Posted on 2024-07-20

1971 Micron-resolution fiber mapping in brain histology independent of sample preparation

Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.

10.1101/2024.03.26.586745 — pathology — Posted on 2024-07-20

1972 Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project

Ge, Y.; Lu, J.; Puiu, D.; Revsine, M.; Salzberg, S. L.

10.1101/2024.05.24.595788 — cancer biology — Posted on 2024-07-20

1973 The roles of an extended N-terminal region and ETD motif in a pump-like cation channelrhodopsin discovered in a lake microbiome

Takaramoto, S.; Fainsod, S.; Nagata, T.; Rozenberg, A.; Beja, O.; Inoue, K.

10.1101/2024.05.16.594411 — biophysics — Posted on 2024-07-20

1974 Deciphering the variation in cuticular hydrocarbon profiles of six European honey bee subspecies

Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.

10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-07-20

1975 Amoeboid cells undergo durotaxis with soft end polarized NMIIA

Kang, C.; Chen, P.; Yi, X.; Li, D.; Hu, Y.; Yang, Y.; Cai, H.; Li, B.; Wu, C.

10.1101/2023.04.13.536664 — cell biology — Posted on 2024-07-20

1976 A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant

Lawrence, G. J.

10.1101/2024.07.01.601607 — molecular biology — Posted on 2024-07-20

1977 An Efficient and Safe Trans-complementation System for MPXV Mimicking Authentic Viral Infection

Liu, J.; Zhu, L.; Mei, L.; Liu, Y.; Qu, Y.; Yuan, Y.; Zhang, F.; Cao, Y.; Zhu, Y.; Tai, W.; Ma, J.; Zheng, M.; Shi, X.; Liu, Y.; Cheng, G.

10.1101/2023.12.29.573498 — microbiology — Posted on 2024-07-20

1978 Fast, lightweight, and accurate metagenomic functional profiling using FracMinHash sketches

Rahman Hera, M.; Liu, S.; Wei, W.; S. Rodriguez, J.; Ma, C.; Koslicki, D.

10.1101/2023.11.06.565843 — bioinformatics — Posted on 2024-07-20

1979 The 9p21.3 coronary artery disease risk locus drives vascular smooth muscle cells to an osteochondrogenic state

Salido, E.; de Medeiros Vieira, C.; Verdezoto Mosquera, J.; Zade, R.; Miller, C. L.; Lo Sardo, V.

10.1101/2024.05.25.595888 — cell biology — Posted on 2024-07-20

1980 Reduced functional fungal communities in two species of sloths (Bradypus variegatus and Choloepus hoffmanni) suggest a link to slow digestion

Chaverri, P.; Escudero-Leyva, E.; Mora-Rojas, D.; Calvo-Obando, A.; Gonzalez, M.; Escalante-Campos, E.; Mesen-Porras, E.; Wicki-Emmenegger, D.; Rojas-Gatjens, D.; Avey-Arroyo, J.; Campos-Hernandez, M.; Castellon, E.; Moreira-Soto, A.; Drexler, J. F.; Chavarria, M.

10.1101/2024.07.19.604311 — microbiology — Posted on 2024-07-20

1981 Developmental changes in mouse motor skill learning and cortical circuitry

Kim, T.; Hooks, B. M.

10.1101/2024.07.19.604309 — neuroscience — Posted on 2024-07-20

1982 Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes

Yanagihara, Y.; Takahashi, M.; Yoshihiro, I.; Kinoshita, T.; Takao, M.; Bamba, T.; Imai, Y.

10.1101/2024.07.17.604010 — developmental biology — Posted on 2024-07-20

1983 Frequency coding of multisensory integration in the local field potentials of the medial pulvinar

Vittek, A.-L.; Juan, C.; Gaillard, C.; Mercier, M.; Girard, P.; Ben Hamed, S.; Cappe, C.

10.1101/2024.07.18.604099 — neuroscience — Posted on 2024-07-20

1984 Invariant synaptic density across species

Ferreira Castro, A.; Cardona, A.

10.1101/2024.07.18.604056 — neuroscience — Posted on 2024-07-20

1985 Central Nervous System Control of breathing in Natural Conversational Turn-Taking

Di Pasquasio, C.; De Pellegrin, L.; Pineaud, A.; Marty, A.; Chaminade, T.

10.1101/2024.07.17.603521 — neuroscience — Posted on 2024-07-20

1986 Encoding of cerebellar dentate neuronal activity during visual attention in rhesus macaques

Flierman, N. A.; Koay, S. A.; van Hoogstraten, W. S.; Ruigrok, T. J. H.; Roelfsema, P.; Badura, A.; De Zeeuw, C. I.

10.1101/2024.07.18.604119 — neuroscience — Posted on 2024-07-20

1987 Systematic identification of Y-chromosome gene functions in mouse spermatogenesis

Subrini, J.; Varsally, W.; Balaguer Balsells, I.; Bensberg, M.; Sioutas, G.; Ojarikre, O.; Maciulyte, V.; Gylemo, B.; Crawley, K.; Courtis, K.; de Rooij, D. G.; Turner, J. M.

10.1101/2024.07.18.604063 — genetics — Posted on 2024-07-19

1988 The Acheulean niche: climate and ecology predict handaxe production in Europe

Leonardi, M.; Lycett, S. J.; Manica, A.; Key, A.

10.1101/2024.07.19.604259 — evolutionary biology — Posted on 2024-07-20

1989 Spatial ciliary signaling regulates the dorsal/ventral regionalization of human brain organoids

Shimada, I. S.; Goto, A.; Hashimoto, Y.; Takase, H.; Itoh, M.; Kato, Y.

10.1101/2024.07.18.604098 — developmental biology — Posted on 2024-07-20

1990 Altered calcium responses and antioxidant properties in Friedreich's ataxia-like cerebellar astrocytes

Marullo, C.; Croci, L.; Giupponi, I.; Rivoletti, C.; Zuffetti, S.; Bettegazzi, B.; Casoni, F.; Cremona, O.; Consalez, G.; Codazzi, F.

10.1101/2024.07.19.604129 — cell biology — Posted on 2024-07-20

1991 Sex-dependent gastrointestinal colonization resistance to MRSA is microbiome and Th17 dependent

Lejeune, A.; Zhou, C.; Ercelen, D.; Putzel, G.; Yao, X.; Guy, A. R.; Pawline, M.; Podkowik, M.; Pironti, A.; Torres, V. J.; Shopsin, B.; Cadwell, K.

10.1101/2024.07.17.603994 — immunology — Posted on 2024-07-19

1992 Brain responses to predictable structure in auditory sequences: From complex regular patterns to tone repetition

Southwell, R.; Tufo, C.; Chait, M.

10.1101/2024.07.18.604117 — neuroscience — Posted on 2024-07-19

1993 The temporal refinement of Dach1 is a key step in the functional maturation of primary somatosensory neurons

Szemes, T.; Sabate San Jose, A.; Azouz, A.; Sitte, M.; Salinas, G.; Achouri, Y.; Kricha, S.; Ris, L.; Red-Horse, K.; Bellefroid, E. J.; Desiderio, S.

10.1101/2024.07.18.604081 — neuroscience — Posted on 2024-07-20

1994 Theoretical Analysis of Nonenzymatic RNA Replication within the Virtual Circular Genome Scenario

Burger, L.; Gerland, U.

10.1101/2024.07.17.603910 — biophysics — Posted on 2024-07-19

1995 The evolution of local adaptation in long-lived species

Habluetzel, L.; Mullon, C.; Schmid, M.

10.1101/2024.07.17.603878 — evolutionary biology — Posted on 2024-07-19

1996 Evolution of intrinsic transcriptional terminators in their genomic context

Toledo-Aparicio, D.; Denisov, S.; Bernard, C.; Redondo, R. A.; Carter, C. C.; Khomarbaghi, Z.; Pittrich, D. A.; Nagy-Staron, A.; Guet, C. C.; Lagator, M.

10.1101/2024.07.17.603904 — evolutionary biology — Posted on 2024-07-19

1997 The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate

Bobola, N.; Darieva, Z.; Zarrineh, P.; Phillips, N.; Mallen, J.; Garcia Mora, A.; Donaldson, I.; Bridoux, L.; Douglas, M.; Dias Henriques, S.; Schulte, D.; Birket, M.

10.1101/2024.07.18.604075 — developmental biology — Posted on 2024-07-19

1998 Loss of PINK1 causes age-dependent mitochondrial trafficking deficits in nigrostriatal dopaminergic neurons through aberrant activation of p38 MAPK

Zhao, J.; Chen, Y.; Zhi, L.; Xu, Q.; Zhang, H.; Li, C.

10.1101/2024.07.17.602426 — neuroscience — Posted on 2024-07-19

1999 A Necrotizing Toxin Promotes Pseudomonas syringae Infection Across Evolutionarily Divergent Plant Lineages

Grenz, K.; Chia, K.-S.; Turley, E. K.; Tyszka, A. S.; Atkinson, R. E.; Reeves, J.; Vickers, M.; Rejzek, M.; Walker, J. F.; Carella, P.

10.1101/2024.07.17.603760 — plant biology — Posted on 2024-07-19

2000 Genome-wide Identification of the Laccase Gene Family in White Jute (Corchorus capsularis): Potential Targets for Lignin Engineering in Bast Fiber

Parida, S.; Jha, D. K.; Kumari, K.; Pradhan, S.; Dey, N.; Majumder, S.

10.1101/2024.07.17.603856 — plant biology — Posted on 2024-07-19

2001 The dynamic and diverse nature of parenchyma cells in the Arabidopsis root during secondary growth

Lyu, M.; Iida, H.; Eekhout, T.; Makela, M.; Muranen, S.; Ye, L.; Vaten, A.; Wybouw, B.; Wang, X.; De Rybel, B.; Mahonen, A. P.

10.1101/2024.07.18.604073 — plant biology — Posted on 2024-07-19

2002 Viral delivery of an RNA-guided genome editor for transgene-free plant germline editing

Weiss, T.; Kamalu, M.; Shi, H.; Li, Z.; Amerasekera, J.; Adler, B. A.; Song, M.; Vohra, K.; Wirnowski, G.; Chitkara, S.; Ambrose, C.; Steinmetz, N.; Sridharan, A.; Sahagun, D.; Banfield, J.; Doudna, J.; Jacobsen, S. E.

10.1101/2024.07.17.603964 — plant biology — Posted on 2024-07-19

2003 Epigenomic manipulation reveals the relationship between locus specific chromatin dynamics and gene expression

Venu, V.; Small, E. M.; Roth, C.; Adikari, S. H.; Vlot, A. H. C.; Sullivan, K. A.; Abeyratne, C. R.; Jacobson, D.; Starkenburg, S. R.; Sanbonmatsu, K. Y.; Steadman, C. R.

10.1101/2024.07.17.603961 — cancer biology — Posted on 2024-07-19

2004 Clarifying misconceptions of biomolecular condensate formation

Hosamane, N.; Hartman, M.; Dubach, M.

10.1101/2024.07.17.603945 — biophysics — Posted on 2024-07-19

2005 RWRtoolkit: multi-omic network analysis using random walks on multiplex networks in any species

Kainer, D.; Lane, M.; Sullivan, K. A.; Miller, J. I.; Cashman, M.; Morgan, M.; Cliff, A.; Romero, J.; Walker, A.; Blair, D. D.; Chhetri, H.; Wang, Y.; Pavicic, M.; Furches, A.; Noshay, J.; Drake, M.; Landry, N.; Ireland, A.; Missaoui, A.; Kang, Y.; Sedbrook, J.; Dehal, P.; Canon, S.; Jacobson, D. A.

10.1101/2024.07.17.603975 — bioinformatics — Posted on 2024-07-19

2006 OPUS-BFactor: Predicting protein B-factor with sequence and structure information

Xu, G.; Yang, Y.; Lv, Y.; Luo, Z.; Wang, Q.; Ma, J.

10.1101/2024.07.17.604018 — bioinformatics — Posted on 2024-07-19

2007 A Hierarchical Method to Analyze Protein-DNA Interfaces

Tagad, A.; Patwari, G. N.

10.1101/2024.07.18.604047 — bioinformatics — Posted on 2024-07-19

2008 CODARFE: Unlocking the prediction of continuous environmental variables based on microbiome

Barbosa, M. C.; da Silva, J. F. M.; Alves, L. C.; Finn, R. D.; Paschoal, A. R.

10.1101/2024.07.18.604052 — bioinformatics — Posted on 2024-07-19

2009 PINDER: The protein interaction dataset and evaluation resource

10.1101/2024.07.17.603980 — bioinformatics — Posted on 2024-07-19

2010 Computational investigation of missense somatic mutations in cancer and potential links to pH-dependence and proteostasis

Sallah, S.; Warwicker, J.

10.1101/2024.07.17.603952 — bioinformatics — Posted on 2024-07-19

2011 Long-read sequencing transcriptome quantification with lr-kallisto

Loving, R. K.; Sullivan, D. K.; Reese, F.; Rebboah, E.; Sakr, J.; Rezaie, N.; Liang, H. Y.; Filimban, G.; Kawauchi, S.; Oakes, C.; Trout, D.; Williams, B. A.; MacGregor, G.; Wold, B.; Mortazavi, A.; Pachter, L.

10.1101/2024.07.19.604364 — bioinformatics — Posted on 2024-07-19

2012 Gradations in protein dynamics captured by experimental NMR are not well represented by AlphaFold2 models and other computational metrics

Gavalda-Garcia, J.; Dixit, B.; Diaz, A.; Ghysels, A.; Vranken, W. F.

10.1101/2024.07.17.603933 — bioinformatics — Posted on 2024-07-19

2013 Deep learning guided design of dynamic proteins

Guo, A. B.; Akpinaroglu, D.; Kelly, M.; Kortemme, T.

10.1101/2024.07.17.603962 — bioengineering — Posted on 2024-07-19

2014 Microbial photoproduction of heptane

BACA-PORCEL, A.; LEGERET, B.; AUROY-TARRAGO, P.; VEILLET, F.; GIACALONE, C.; Cuine, S.; Palakiyem SAMIRE, P.; MOULIN, S.; LI-BEISSON, Y.; BEISSON, F.; Sorigue, D.

10.1101/2024.07.17.603920 — bioengineering — Posted on 2024-07-19

2015 Statistical Survey of Chemical and Geometric Patterns on Protein Surfaces as a Blueprint for Protein-mimicking Nanoparticles

McBride, J. M.; Koshevarnikov, A.; Siek, M.; Grzybowski, B.; Tlusty, T.

10.1101/2024.07.18.604221 — biochemistry — Posted on 2024-07-19

2016 Structural basis for allosteric regulation of the proteasome core particle

Turner, M.; Uday, A. B.; Velyvis, A.; Rennella, E.; Zeytuni, N.; Vahidi, S.

10.1101/2024.07.19.604198 — biochemistry — Posted on 2024-07-19

2017 Twinfilin is a non-processive depolymerase which synergizes with formin to dramatically accelerate actin filament uncapping by 300-fold

Reddy, V.; Arya, A.; Shekhar, S.

10.1101/2024.07.19.604324 — biochemistry — Posted on 2024-07-19

2018 Synthesis of K+ channel radioligand 5-methyl-3-fluoro-4-aminopyridine and PET imaging in mice

Sun, Y.; Ramos-Torres, K. M.; Takahashi, K.; Zhang, L. L.; Brugarolas, P. M.

10.1101/2024.07.19.604281 — biochemistry — Posted on 2024-07-19

2019 Chemically di-ubiquitylated H1 variants reveal position-dependent stimulation of the DNA repair protein RNF168

Franz, P.; Delvaux de Fenffe, C.; Fierz, B.

10.1101/2024.07.19.604272 — biochemistry — Posted on 2024-07-19

2020 Biased agonism of carvedilol in the beta1-adrenergic receptor is governed by conformational exclusion

Abiko, L. A.; Petrovic, I.; Tatli, M.; Desai, S.; Stahlberg, H.; Spang, A.; Grzesiek, S.

10.1101/2024.07.19.604263 — biochemistry — Posted on 2024-07-19

2021 Ascorbic acid and gallic acid and mitigate behavioural deficits and loss of cerebellar myelin induced by Bisphenol-A in Wistar rats.

Adigun, K. O.; Ehinmowo, M. I.; Folarin, O.; Adebiyi, O. E.

10.1101/2024.07.17.603899 — animal behavior and cognition — Posted on 2024-07-19

2022 Ecological risk-taking across age in Barbary macaques

Bosshard, T. C.; Mundry, R.; Fischer, J.

10.1101/2024.07.19.603766 — animal behavior and cognition — Posted on 2024-07-19

2023 Quantifying higher-order epistasis: beware the chimera

Chitra, U.; Arnold, B. J.; Raphael, B.

10.1101/2024.07.17.603976 — genetics — Posted on 2024-07-19

2024 Optimal thermal niche-tracking buffers wild great tits against climate change

Lopez-Idiaquez, D.; Cole, E. F.; Regan, C. E.; Sheldon, B. C.

10.1101/2024.07.18.603942 — evolutionary biology — Posted on 2024-07-19

2025 Ancient Borrelia genomes document the evolutionary history of louse-borne relapsing fever

Swali, P.; Booth, T.; Tan, C. C. S.; McCabe, J.; Anastasiadou, K.; Barrington, C.; Borrini, M.; Bricking, A.; Buckberry, J.; Buster, L.; Carlin, R.; Gilardet, A.; Glocke, I.; Irish, J.; Kelly, M.; King, M.; Petchey, F.; Peto, J.; Silva, M.; Speidel, L.; Tait, F.; Teoaca, A.; Valoriani, S.; Williams, M.; Madgwick, R.; Mullan, G.; Wilson, L.; Cootes, K.; Armit, I.; Gutierrez, M. G.; van Dorp, L.; Skoglund, P.

10.1101/2024.07.18.603748 — evolutionary biology — Posted on 2024-07-19

2026 DoubleTrouble: Multiple infections and the coevolution of virulence-resistance in structured host-parasite populations.

LOMBARD, J. D.; Massol, F.; Lion, S.

10.1101/2024.07.17.603867 — evolutionary biology — Posted on 2024-07-19

2027 Using state space models to understand trait evolution in fossil lineages

Hunt, G.; Martinez Rivera, W.; Hopkins, M.; Fricks, J.; Sterner, B.

10.1101/2024.07.17.603977 — evolutionary biology — Posted on 2024-07-19

2028 Reproductive resource allocation correlates with successful global invasion of a mosquito species

Khorramnejad, A.; Alfaro, C. C.; Quaranta, S.; Lozada-Chavez, A. N.; Gasmi, L.; Perdomo, H. D.; Chiarelli, L. R.; Bonizzoni, M.

10.1101/2024.07.18.604133 — evolutionary biology — Posted on 2024-07-19

2029 Spatio-temporal dynamics of attacks around deaths of wolves: A statistical assessment of lethal control efficiency in France

Grente, O.; Opitz, T.; Duchamp, C.; Drouet-Hoguet, N.; Chamaille-Jammes, S.; Gimenez, O.

10.1101/2024.07.18.604079 — ecology — Posted on 2024-07-19

2030 Metabolites reflect variability introduced by mesoscale eddies in the North Pacific Subtropical Gyre

Kumler, W.; Qin, W.; Lundeen, R. A.; Barone, B.; Carlson, L. T.; Ingalls, A. E.

10.1101/2024.07.18.604132 — ecology — Posted on 2024-07-19

2031 Three-dimensional culture in a bioengineered matrix and somatic cell complementation to improve growth and survival of bovine preantral follicles

Candelaria, J. I.; Botigelli, R. C.; Guiltinan, C.; Shikanov, A.; Denicol, A. C.

10.1101/2024.07.18.604061 — developmental biology — Posted on 2024-07-19

2032 Enhanced Visualization of Influenza A Virus Entry Using Virus-View Atomic Force Microscopy

Yoshida, A.; Uekusa, Y.; Suzuki, T.; Bauer, M.; Sakai, N.; Yamauchi, Y.

10.1101/2024.07.19.603848 — cell biology — Posted on 2024-07-19

2033 Small Extracellular Vesicles from Human Bone Marrow Mesenchymal Stromal Cells enhance migration and regulate gene expression of reparative mechanisms in human dermal fibroblasts

Lei, R.; Borges da Silva, T.; Cui, Z.; Ye, H.

10.1101/2024.07.19.601214 — cell biology — Posted on 2024-07-19

2034 The RpfB switch is a novel B12-sensing riboswitch regulating (non-replicating) persistence in Mycobacterium tuberculosis.

Kipkorir, T.; Polgar, P.; D'Halluin, A.; Gap-Gaupool, B.; Makarov, V.; Mukamolova, G.; Arnvig, K. B.

10.1101/2024.07.19.603033 — molecular biology — Posted on 2024-07-19

2035 Long range regulation of transcription scales with genomic distance in a gene specific manner

Jensen, C. L.; Chen, L.-F.; Swigut, T.; Crocker, O. J.; Yao, D.; Bassik, M. C.; Ferrell, J.; Boettiger, A.; Wysocka, J.

10.1101/2024.07.19.604327 — molecular biology — Posted on 2024-07-19

2036 Mesoscale chromatin confinement facilitates target search of pioneer transcription factors in live cells

Wang, Z.; Wang, B.; Niu, D.; Yin, C.; Bi, Y.; Cattoglio, C.; Loh, K. M.; Lavis, L. D.; Ge, H.; Deng, W.

10.1101/2024.07.18.604200 — molecular biology — Posted on 2024-07-19

2037 Lipotoxicity Induces Beta Cell Small Extracellular Vesicle-mediated Beta Cell Dysfunction

Roy, A.; Hoff, A.; Her, T. K.; Ariyaratne, G.; Sankaran Rajagopalan, K.; Brown, M. R.; Soto-Gonzalez, A.; Matveyenko, A. V.; Javeed, N.

10.1101/2024.07.19.604353 — molecular biology — Posted on 2024-07-19

2038 Extracts of food and medicinal plants sold in Moroccan markets induce apoptosis-like in Toxoplasma gondii tachyzoites in vitro

Elkoraichi, I.; Moire, N.; Rais, S.; Dimier-Poisson, I.; Daoudi, F.; Debierre-Grockiego, F.

10.1101/2024.07.19.603849 — microbiology — Posted on 2024-07-19

2039 Rapid Detection of Active Coronavirus Infection by Lateral Flow Test Strips: A New Approach to Distinguish Replicating Viruses from Non-Replicating Viruses

Davis, D.; Lamb, C. H.; Myhrvold, C. A.; Ullah, H.

10.1101/2024.07.18.604218 — microbiology — Posted on 2024-07-19

2040 SARS-CoV-2 B Epitope-Guided Neoantigen NanoVaccines Enhance Tumor-Specific CD4/CD8 T Cell Immunity Through B Cell Antigen Presentation

Li, C.; Mao, S.; Montemayor, Z.; Traore, M. D. M.; Duran, A.; Ke, F.; Djibo, M.; Wen, H.; Gao, W.; Sun, D.

10.1101/2024.07.18.604163 — immunology — Posted on 2024-07-19

2041 Immune disease dialogue of chemokine-based cell communications as revealed by single-cell RNA sequencing meta-analysis

Rahman, M. F.; Kurlovs, A. H.; Vodnala, M.; Meibalan, E.; Means, T. K.; Nouri, N.; de Rinaldis, E.; Savova, V.

10.1101/2024.07.17.603936 — immunology — Posted on 2024-07-19

2042 Discrimination of Jamaican fruit bat lymphocytes by flow cytometry

Burke, B. E.; Rocha, S. M.; Campbell, C. L.; Creissen, E.; Tjalkens, R.; Ma, W.; Henao-Tamayo, M. I.; Schountz, T.

10.1101/2024.07.18.604131 — immunology — Posted on 2024-07-19

2043 The noncoding circular RNA circHomer1 regulates developmental experience-dependent plasticity in mouse visual cortex

10.1101/2024.07.19.603416 — neuroscience — Posted on 2024-07-19

2044 Surfing beta burst waveforms to improve motor imagery-based BCI

Papadopoulos, S.; Darmet, L.; Szul, M. J.; Congedo, M.; Bonaiuto, J. J.; Mattout, J.

10.1101/2024.07.18.604064 — neuroscience — Posted on 2024-07-19

2045 High-throughput discovery of regulatory effector domains in human RNA-binding proteins

Thurm, A. R.; Finkel, Y.; Andrews, C.; Cai, X. S.; Benko, C.; Bintu, L.

10.1101/2024.07.19.604317 — synthetic biology — Posted on 2024-07-19

2046 Preventing escape and malfunction of recoded cells due to tRNA base changes

Chiappino-Pepe, A.; Radford, F.; Budnik, B.; Tas, H.; Augustin, T. L.; Burgess, H. M.; Moret, M.; Dharani, A. M.; Zheng, Q.; Fan, W.; Afrikawala, M. M.; Thapa, S.; Kuru, E.; Narasimhan, K.; Marchand, J. A.; Perrotta, R. M.; Stokes, J. M.; Lunshof, J. E.; Aach, J. D.; Tam, J. M.; Church, G. M.

10.1101/2024.07.18.604179 — synthetic biology — Posted on 2024-07-19

2047 A modular cell-free protein biosensor platform using split T7 RNA polymerase

McSweeney, M. A.; Patterson, A. T.; Loeffler, K.; Cuellar Lelo de Larrea, R.; McNerney, M. P.; Kane, R. S.; Styczynski, M. P.

10.1101/2024.07.19.604303 — synthetic biology — Posted on 2024-07-19

2048 Disentangling the regulatory response of Agrobacterium tumefaciens CHLDO to glyphosate for engineering whole-cell phosphonate biosensors

Masotti, F.; Krink, N.; Lencina, N.; Gottig, N.; Ottado, J.; Nikel, P. I.

10.1101/2024.07.19.604230 — synthetic biology — Posted on 2024-07-19

2049 Prevention of ribozyme catalysis through cDNA synthesis enables accurate RT-qPCR measurements of context-dependent ribozyme activity

Alperovich, N. Y.; Vasilyeva, O. B.; Schaffter, S. W.

10.1101/2024.07.19.604288 — synthetic biology — Posted on 2024-07-19

2050 Evaluation of intercellular and extracellular synthesis of biogenic amines by the aquatic moss Vesicularia dubyana

Belyshenko, A. Y.; Morgunova, M. M.; Malygina, E. V.; Dmitrieva, M. E.; Imidoeva, N. A.; Shelkovnikova, V. N.; Telnova, T. Y.; Vlasova, A. A.; Vavilina, T. N.; Tretyakova, A. V.; Axenov-Gribanov, D. V.

10.1101/2024.07.19.604072 — plant biology — Posted on 2024-07-19

2051 Prebiotic Supplementation Modulates the Gut Microbiome for Improving Oral Antipsychotic Bioavailability

Collins, K.; Kamath, S.; Meola, T.; Wignall, A.; Joyce, P.

10.1101/2024.07.17.604016 — pharmacology and toxicology — Posted on 2024-07-19

2052 Comparative analysis of STP6 and STP10 rationalizes molecular selectivity in Sugar Transport Proteins

Andersen, C. G.; Bavnhoj, L.; Brag, S.; Driller, J. H.; Pedersen, B. P.

10.1101/2024.07.19.604285 — biochemistry — Posted on 2024-07-19

2053 Structural characterization of two full length γδTCR/CD3 complexes

Hoque, M.; Grigg, J. B.; Ramlall, T.; Jones, J.; McGoldrick, L. L.; Olson, W. C.; Lin, J. C.; Smith, E.; Franklin, M. C.; Zhang, T.; Saotome, K.

10.1101/2024.07.19.604350 — biochemistry — Posted on 2024-07-19

2054 High-Recovery Desalting Tip Columns for a Wide Variety of Peptides in Mass Spectrometry-based Proteomics

Kanao, E.; Tanaka, S.; Tomioka, A.; Tanigawa, T.; Kubo, T.; Ishihama, Y.

10.1101/2024.07.19.604362 — biochemistry — Posted on 2024-07-19

2055 Accurate Predictions of Phase Separating Proteins at Single Amino Acid Resolution

Monti, M.; Fiorentino, J.; Vrachnos, D.; Bini, G.; Cotrufo, T.; Sanchez, N.; Armaos, A.; Tartaglia, G. G.

10.1101/2024.07.19.602785 — biochemistry — Posted on 2024-07-19

2056 Revisiting Sodium Phosphotungstate and Ammonium Molybdate as non-radioactive negative staining agents for single particle analysis

Gunkel, M.; Macha, A.; Behrmann, E.

10.1101/2024.07.19.604222 — biochemistry — Posted on 2024-07-19

2057 Early evolution of the BA.2.86 variant sheds light on the origins of highly divergent SARS-CoV-2 lineages

Escalera Zamudio, M.; Tan, C.; van Dorp, L.; Balloux, F.

10.1101/2024.07.18.604213 — evolutionary biology — Posted on 2024-07-19

2058 Enhancing gRNA Transcript levels by Reducing the Scaffold Poly-T Tract for Optimal SpCas9- and SaCas9-mediated Gene Editing

Chey, Y. C. J.; Gierus, L.; Lushington, C.; Arudkumar, J. C.; Geiger, A.; Staker, L. G.; Robertson, L. J.; Pfitzner, C.; Kennedy, J. G.; Lee, R. H. B.; Godahewa, G. I.; Thomas, P. Q.; Adikusuma, F.

10.1101/2024.07.19.604224 — molecular biology — Posted on 2024-07-19

2059 Engineering the novel extremophile alga Chlamydomonas pacifica for high lipid and high starch production as a path to developing commercially relevant strains

Gupta, A.; Dutra Molino, J. V.; Wnuk-Fink, K. M.; Bruckbauer, A.; Tessman, M.; Kang, K.; Diaz, C. J.; Saucedo, B.; Malik, A.; Mayfield, S. P.

10.1101/2024.07.18.604193 — molecular biology — Posted on 2024-07-19

2060 High-throughput method rapidly characterizes hundreds of novel antibiotic resistance mutations

Jago, M. J.; Soley, J. K.; Denisov, S.; Walsh, C. J.; Gifford, D. R.; Howden, B. P.; Lagator, M.

10.1101/2024.07.19.604246 — microbiology — Posted on 2024-07-19

2061 Engineering microbial consortia: uptake and leakage ratedifferentially shape community arrangement and composition

Pignon, E.; Hollo, G.; Steiner, T.; van Vliet, S.; Schaerli, Y.

10.1101/2024.07.19.604250 — microbiology — Posted on 2024-07-19

2062 Cell wall-resident PIR proteins show an inverted architecture in Neurospora crassa, but keep their role as wall stabilizers

Montano-Silva, P.; Callejas-Negrete, O. A.; Pereira-Santana, A.; Verdin, J.

10.1101/2024.07.18.603779 — microbiology — Posted on 2024-07-19

2063 Multiple dermal cell types support productive infection and dynamic translocation of infectious Ebola virus to the apical surface of human skin

Messingham, K.; Richards, P. T.; Fleck, A.; Patel, R. A.; Djurkovic, M.; Elliff, J.; Connell, S.; Gonzalez, J. P. M.; Gourronc, F. A.; Dillard, J. A.; Davey, R. A.; Klingelhutz, A. J.; Shtanko, O.; Maury, W.

10.1101/2024.07.19.604135 — microbiology — Posted on 2024-07-19

2064 Blood-based detection of MMP11 as a marker of prostate cancer progression regulated by the ALDH1A1-TGF-β1 signaling mechanism

Gorodetska, I.; Lukiyanchuk, V.; Gawin, M.; Sliusar, M.; Linge, A.; Lohaus, F.; Hölscher, T.; Erdmann, K.; Fuessel, S.; Borkowetz, A.; Reardon, M.; Choudhury, A.; Antonelli, Y.; Leal-Egana, A.; Köseer, A. S.; Kahya, U.; Püschel, J.; Klusa, D.; Peitzsch, C.; Kronstein-Wiedemann, R.; Tonn, T.; Thomas, C.; Widłak, P.; Pietrowska, M.; Krause, M.; Dubrovska, A.

10.1101/2024.07.16.603771 — cancer biology — Posted on 2024-07-19

2065 A critical role of protein damage response in mediating cancer drug resistance

Deng, C.

10.1101/2024.07.17.603840 — cancer biology — Posted on 2024-07-19

2066 Epigenetics is all you need: A Transformer to decode chromatin structural compartments from the epigenome

Dodero-Rojas, E.; Contessoto, V. d. G.; Fehlis, Y.; Malaya, N.; Onuchic, J.

10.1101/2024.07.17.603864 — genomics — Posted on 2024-07-19

2067 Diversified global vegetable oil production can mitigate climate change and increase other environmental and socioeconomic benefits.

Zeng, S.; Wanger, T. C.

10.1101/2024.07.16.603827 — ecology — Posted on 2024-07-19

2068 The role of YAP/TAZ signaling in dendritic cell-mediated pathogenesis of insulin resistance and non-alcoholic fatty liver disease

Schcolnik-Cabrera, A.; Lee, M.; Dzierlaga, K.; Basso, P.; Strachan, E.; Zhu, M.; Akbari, M.; Clemente-Casares, X.; Tsai, S.

10.1101/2024.07.16.603813 — immunology — Posted on 2024-07-19

2069 Conditional Sequence-Structure Integration: A Novel Approach for Precision Antibody Engineering and Affinity Optimization

Jamialahmadi, B.; Chamankhah, M.; Kohandel, M.; Ghodsi, A.

10.1101/2024.07.16.603820 — immunology — Posted on 2024-07-19

2070 Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function

Brown, M.; Thirawatananond, P.; Peters, L.; Kern, E.; Vijay, S.; Sachs, L.; Posgai, A. L.; Brusko, M.; Shapiro, M.; Mathews, C. E.; Bacher, R. E.; Brusko, T.

10.1101/2024.07.16.603756 — immunology — Posted on 2024-07-19

2071 Social Decision Preferences for Close Others are Embedded in Neural and Linguistic Representations

Guassi Moreira, J. F.; Esparza, L. C.; Silvers, J. A.; Parkinson, C.

10.1101/2024.07.16.603808 — neuroscience — Posted on 2024-07-19

2072 Mapping activity and functional organisation of the motor and visual pathways using ADC-fMRI in the human brain

Nguyen-Duc, J.; De Riedmatten, I.; Spencer, A.; Perot, J.-B.; Olszowy, W.; Jelescu, I.

10.1101/2024.07.17.603726 — neuroscience — Posted on 2024-07-19

2073 Oscillations create groove: A reservoir model for learning complex drumming performances

Kawai, Y.; Fujii, S.; Asada, M.

10.1101/2024.07.17.603863 — neuroscience — Posted on 2024-07-19

2074 SSRI antidepressant citalopram reverses the Warburg effect to inhibit hepatocellular carcinoma by directly targeting GLUT1

Dong, F.; He, K.; Zhang, S.; Song, K.; Jiang, L.; Hu, L.; Li, Q.; Zhang, X.-L.; Zhang, N.; Li, B.-T.; Zhu, L.-L.; Li, J.; Feng, M.; Gao, Y.; Chen, J.; Hu, X.; Wang, J.; Jiang, C.; Zhu, H.; Da, L.; Ji, J.; Bao, Z.; Jiang, S.-H.

10.1101/2024.07.17.603851 — cancer biology — Posted on 2024-07-19

2075 Gene Function Revealed at the Moment of Stochastic Gene Silencing

Gupta, S.; Cai, J. J.

10.1101/2024.07.16.603770 — bioinformatics — Posted on 2024-07-19

2076 A BLAST from the past: revisiting blastp's E-value

Lu, Y.; Noble, W. S.; Keich, U.

10.1101/2024.07.16.603405 — bioinformatics — Posted on 2024-07-19

2077 BLM Aggregation-Prone Ability and Similarity to Intrinsically Disordered Proteins Indicate its Potential Role in Neurodegenerative Diseases

Sharma, S.; Yadav, S. S.; Nair, R. R.

10.1101/2024.07.16.603833 — bioinformatics — Posted on 2024-07-19

2078 Representing Transcription Factor Dimer Binding Sites Using Forked-Position Weight Matrices and Forked-Sequence Logos

Matthew, D.; Roberto, T.-M.; Aida, G.-K.; Quy, X. X. L.; Walter, S.; Hamid, U.; Morgane, T.-C.; Sudhakar, J.; Denis, T.; Touati, B.

10.1101/2024.07.16.603695 — bioinformatics — Posted on 2024-07-19

2079 Wearable facemask-attached disposable printed sensor arrays for point-of-need monitoring of ammonia in breath

Barandun, G.; Sanli, A.; Yap, C. L.; Collins, A. S. P.; Grell, M.; Kasimatis, M.; Levy, J.; Guder, F.

10.1101/2024.07.16.603629 — bioengineering — Posted on 2024-07-19

2080 Probability of Lateral Instability While Walking on Winding Paths

Render, A. C.; Cusumano, J. P.; Dingwell, J. B.

10.1101/2024.07.16.603791 — bioengineering — Posted on 2024-07-19

2081 Cross-Tissue Comparison of Epigenetic Aging Clocks in Humans

Apsley, A. T.; Ye, Q.; Caspi, A.; Chiaro, C.; Etzel, L.; Hastings, W. J.; Heim, C. C.; Kozlosky, J.; Noll, J.; Schreier, H. M. C.; Shenk, C. E.; Sugden, K.; Shalev, I.

10.1101/2024.07.16.603774 — genomics — Posted on 2024-07-19

2082 The first complete mitochondrial genome of tjakura (Great Desert Skink, Liopholis kintorei)

Thuo, D.; Macgregor, N. A.; Keogh, J. S.; Goumas, M.; Swan, S.; Guest, T.; Doerr, E. D.; Wallace, J.; Paltridge, R.; Kenny, J.; Merson, S. D.; Leo, J.

10.1101/2024.07.17.603866 — genomics — Posted on 2024-07-19

2083 Pf-HaploAtlas: an interactive web app for spatiotemporal analysis of P. falciparum genes

Lee, C.; Ünlü, E. S.; White, N. F.; Almagro-Garcia, J.; Ariani, C.; Pearson, R. D.

10.1101/2024.07.16.603783 — genomics — Posted on 2024-07-19

2084 PAX proteins in silico prediction in Lissachatina fulica

Dominova, I. N.; Golovneva, K.; Korshunova, N.; Zhukov, V. V.

10.1101/2024.07.16.603807 — evolutionary biology — Posted on 2024-07-19

2085 Alternative splicing controls pan-neuronal homeobox gene expression

Leyva-Diaz, E.; Cesar, M.; Pe, K.; Jorda-Llorens, J. I.; Valdivia, J.; Hobert, O.

10.1101/2024.07.16.603806 — developmental biology — Posted on 2024-07-19

2086 Mll4 regulates postnatal palate growth and midpalatal suture development

Lee, J.-M.; Jung, H.; de Paula Machado Pasqua, B.; Park, Y.; Jeon, S.; Lee, S.-K.; Lee, J. W.; Kwon, H.-J. E.

10.1101/2024.07.16.603832 — developmental biology — Posted on 2024-07-19

2087 Engineered NKG2C+ NK-like T cells exhibit superior antitumor efficacy while mitigating cytokine release syndrome

Lupo, K. B.; Panjwani, M. K.; Shahid, S.; Sottile, R.; Lawry, C.; Kolk, G.; Kontopolous, T.; Daniyan, A. F.; Chandran, S. S.; Klebanoff, C. A.; Hsu, K. C.

10.1101/2024.07.16.603785 — immunology — Posted on 2024-07-19

2088 Temporal asymmetry of neural representations predicts memory decisions

Ye, Z.; Zhao, Y.; Allen, E. J.; Naselaris, T.; Kay, K.; Hutchinson, J. B.; Kuhl, B. A.

10.1101/2024.07.16.603778 — neuroscience — Posted on 2024-07-19

2089 Visual cues for moisture perception of facial skin: Enhancing high-frequency components of skin lightness increases perceived dryness

Hasegawa, Y.; Tamura, H.; Kanematsu, T.; Yamada, Y.; Ishiguro, Y.; Nakauchi, S.; Minami, T.

10.1101/2024.07.16.603839 — neuroscience — Posted on 2024-07-19

2090 Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation

Sun, E. D.; Zhou, O. Y.; Hauptschein, M.; Rappoport, N.; Xu, L.; Navarro Negredo, P.; Liu, L.; Rando, T. A.; Zou, J.; Brunet, A.

10.1101/2024.07.16.603809 — neuroscience — Posted on 2024-07-19

2091 Perturbed pediatric serum metabolome in mild and severe dengue disease

Soma, P. S.; Gullberg, R. C.; Graham, B.; Islam, M. N.; Balmaseda, A.; Blair, C. D.; Beaty, B.; Belisle, J. T.; Harris, E.; Perera, R.

10.1101/2024.07.16.603788 — systems biology — Posted on 2024-07-19

2092 Cellulose synthesis in Arabidopsis by heterologous expression of lower plants CESA proteins

Kumar, M.; Gomez, L.; Turner, S. R.

10.1101/2024.07.16.603775 — plant biology — Posted on 2024-07-19

2093 A viscoelastic-plastic deformation model of hemisphere-like tip growth in Arabidopsis zygotes

Kang, Z.; Nonoyama, T.; Ishimoto, Y.; Matsumoto, H.; Nakagawa, S.; Ueda, M.; Tsugawa, S.

10.1101/2024.07.17.603843 — plant biology — Posted on 2024-07-19

2094 Deletion of the endothelial glycocalyx component endomucin leads to impaired glomerular structure and function

Hu, Z.; Cano, I.; Lei, F.; Liu, J.; Bossardi Ramos, R.; Gordon, H.; Paschalis, E. I.; Saint-Geniez, M.; Ng, Y. S. E.; D'Amore, P. A.

10.1101/2024.07.16.603749 — pathology — Posted on 2024-07-19

2095 FLASH radiotherapy using high-energy X-rays: validation of the FLASH effect triggered by a compact single high-energy X-ray source device

Lin, B.; Du, H.; Yang, Y.; Hao, X.; Gao, F.; Liang, Y.; Tang, W.; Xu, H.; Tang, M.; Liao, Y.; Wang, D.; Lin, B.; Zhu, Y.; Zhang, Y.; Li, J.; zhou, z.; Wang, J.; Wu, D.; Du, X.

10.1101/2024.07.16.603758 — cancer biology — Posted on 2024-07-19

2096 Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis

Cai, Y.; To, S. K. Y.; Guan, Z.; Tong, Y.; Zhang, J.; Ip, P. P. C.; Peng, L.; Wong, A. S. T.

10.1101/2024.07.16.603672 — cancer biology — Posted on 2024-07-19

2097 TESTING THE USE OF XRCC6 GENE IN PHYLOGENETIC ANALYSES

CELIK, R.

10.1101/2024.07.16.603754 — bioinformatics — Posted on 2024-07-19

2098 Microphysiological system modeling pericyte-induced temozolomide resistance in glioblastoma

Maity, S.; Jewell, C.; Yilgor, C.; Kawakita, S.; Sharma, S.; Gomez, A.; Mecwan, M.; Falcone, N.; Ermis, M.; Monirizad, M.; Hosseinzadeh Kouchehbaghi, N.; Zehtabi, F.; Khorsandi, D.; Dokmeci, M. R.; Moniz-Garcia, D.; Quinones-Hinojosa, A.; Khademhosseini, A.; Jucaud, V.

10.1101/2024.07.16.603611 — bioengineering — Posted on 2024-07-19

2099 Programming aliphatic polyester degradation by engineered bacterial spores

Cui, Z.; Kawada, M.; Hui, Y.; Sim, S.

10.1101/2024.07.16.603759 — bioengineering — Posted on 2024-07-19

2100 Design of two-stage multi-drug chemotherapy schedules using replicator game dynamics

Stuckey, K.; Newton, P. K.

10.1101/2024.07.16.603768 — evolutionary biology — Posted on 2024-07-19

2101 Adult caudal fin shape is imprinted in the embryonic fin fold

Surette, E.; Donahue, J.; Robinson, S.; McKenna, D.; Soto Martinez, C.; Fitzgerald, B.; Karlstrom, R.; Cumplido, N.; McMenamin, S. K.

10.1101/2024.07.16.603744 — developmental biology — Posted on 2024-07-19

2102 The asymmetric expression of HSPA2 in blastomeres governs the first embryonic cell-fate decision

Gao, J.; Wang, J.; Liu, S.; Song, J.; Zhang, C.; Liu, B.; Wu, K.

10.1101/2024.07.16.603746 — developmental biology — Posted on 2024-07-19

2103 RAB12-LRRK2 Complex Suppresses Primary Ciliogenesis and Regulates Centrosome Homeostasis in Astrocytes

Li, X.; Zhu, H.; Huang, B. T.; Li, X.; Kim, H.; Tan, H.; Zhang, Y.; Choi, I.; Peng, J.; Xu, P.; Sun, J.; Yue, Z.

10.1101/2024.07.17.603999 — neuroscience — Posted on 2024-07-19

2104 All-optical mapping of Ca2+ transport and homeostasis in dendrites

Hayward, R. F.; Cohen, A. E.

10.1101/2024.07.16.603652 — neuroscience — Posted on 2024-07-19

2105 Beyond Auditory Relay: Dissecting the Inferior Colliculus's Role in Sensory Prediction, Cognitive Decision-Making, and Reward Prediction

Du, X.; Xu, H.; Song, P.; Zhai, Y.; Ye, H.; Bao, X.; Huang, Q.; Tanigawa, H.; Tu, Z.; Chen, P.; Zhao, X.; P. Rauschecker, J.; Yu, X.

10.1101/2024.07.16.603747 — neuroscience — Posted on 2024-07-19

2106 Social odors drive hippocampal CA2 place cell responses to social stimuli

Robson, E.; Donahue, M. M.; Mably, A. J.; Demetrovich, P. G.; Hewitt, L. T.; Colgin, L. L.

10.1101/2024.07.16.603738 — neuroscience — Posted on 2024-07-19

2107 Mechanism of auxin-dependent gene regulation through composite auxin response elements

Novikova, D. D.; Omelyanchuk, N.; Korosteleva, A.; Albrecht, C.; Lavrekha, V. V.; Weijers, D.; Mironova, V.

10.1101/2024.07.16.603724 — plant biology — Posted on 2024-07-19

2108 Endomucin knockout leads to delayed retinal vascular development and reduced ocular pathological neovascularization

Hu, Z.; Cano, I.; Lennikov, A.; Wild, M.; Gupta, U.; Ng, E. Y. S.; D'Amore, P.

10.1101/2024.07.16.603729 — pathology — Posted on 2024-07-19

2109 Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies

Frank, S.; Persse, T.; Coleman, I. M.; Bankhead, A.; Li, D.; DeSarkar, N.; Wilson, D.; Rudoy, D.; Vashisth, M.; Galipeau, P.; Yang, M.; Hanratty, B.; Dumpit, R.; Morrissey, c.; Corey, E.; Montgomery, R.; Haffner, M.; Pritchard, C.; Vasioukhin, V.; Ha, G.; Nelson, P. S.

10.1101/2024.07.16.603734 — cancer biology — Posted on 2024-07-19

2110 Logical Network Perturbations Guide Precise Target Prioritization for Drug Development

Sinha, S.; McLaren, E. G.; Mullick, M.; Singh, S.; Boland, B. S.; Ghosh, P.

10.1101/2024.07.16.602603 — bioinformatics — Posted on 2024-07-19

2111 ADToolbox: Incorporating Metagenomics Data for Improved Prediction of Anaerobic Digestion Dynamics

Ghadermazi, P.; Rico, J. L.; Rimelman, E.; Stenmark, S.; Reardon, K. F.; De Long, S. K.; Chan, S. H. J.

10.1101/2024.07.16.603753 — bioengineering — Posted on 2024-07-19

2112 A cafeteria diet blunts effects of exercise on adult hippocampal neurogenesis but not neurogenesis-dependent behaviours in adult male rats

Nota, M. H.; Dohm-Hansen, S.; Nicolas, S.; Harris, E. P.; Foley, T.; Nolan, Y. M.; O'Leary, O. F.

10.1101/2024.07.16.603714 — neuroscience — Posted on 2024-07-19

2113 Altered resting-state brain entropy (BEN) by rTMS across the human cortex

Song, D.-H.; Deng, X.-P.; Shang, Y.-Q.; Chang, D.; Wang, Z.

10.1101/2024.07.16.601109 — neuroscience — Posted on 2024-07-19

2114 Neural dynamics underlying minute-timescale persistent behavior in the human brain

Courellis, H.; Valiante, T. A.; Mamelak, A. N.; Adolphs, R.; Rutishauser, U.

10.1101/2024.07.16.603717 — neuroscience — Posted on 2024-07-19

2115 Thyroid hormones maintain parvalbumin neuron functions in mouse neocortex

Ren, J.; Markossian, S.; Guyot, R.; Aubert, D.; Li, D.; Cauli, B.; Riet, F.; Wong, J.; Flamant, F.; Richard, S.

10.1101/2024.07.16.603713 — neuroscience — Posted on 2024-07-19

2116 Differential representation of active and passive touch in mouse somatosensory thalamus

Sumser, A.; Isaias-Camacho, E.; Mease, R. A.; Groh, A.

10.1101/2024.07.16.603697 — neuroscience — Posted on 2024-07-19

2117 Stomatal patterning is differently regulated in adaxial and abaxial epidermis in Arabidopsis

Jalakas, P.; Tulva, I.; Berzina, N. M.; Horak, H.

10.1101/2024.02.22.581564 — plant biology — Posted on 2024-07-19

2118 Gibberellic acid and light effects on seed germination in the seagrass Zostera marina

Pieraccini, R.; Whatley, L.; Koedam, N.; Dierick, J.; Vanreusel, A.; Dolch, T.; Van der Stocken, T.

10.1101/2024.07.16.603723 — plant biology — Posted on 2024-07-19

2119 A foundation model for generalizable cancer diagnosis and survival prediction from histopathological images

Yu, Z.; Yang, Z.; Wei, T.; Liang, Y.; Yuan, X.; Gao, R.; Xia, Y.; Zhou, J.; Zhang, Y.

10.1101/2024.05.16.594499 — pathology — Posted on 2024-07-19

2120 The molecular impact of cigarette smoking resembles aging across tissues

Ramirez, J. M.; Ribeiro, R.; Soldatkina, O.; Moraes, A.; Garcia-Perez, R.; Ferreira, P. G.; Mele, M.

10.1101/2024.03.14.585016 — bioinformatics — Posted on 2024-07-19

2121 Modeling causal signal propagation in multi-omic factor space with COSMOS

Dugourd, A.; Lafrenz, P.; Mananes, D.; Paton, V.; Fallegger, R.; Kroger, A.-C.; Turei, D.; Shtylla, B.; Saez-Rodriguez, J.

10.1101/2024.07.15.603538 — bioinformatics — Posted on 2024-07-19

2122 Sensing endogenous RNA in living human cells using a CRISPR-activated protease

Blumenstock, K.; Hoch, A.; Hinterlang, L. D.; Caroline, F.; Schneberger, N.; Hagelueken, G.; Schmid-Burgk, J. L.

10.1101/2024.07.17.603943 — bioengineering — Posted on 2024-07-19

2123 Hierarchical structural organization in bioinspired peptide coacervate microdroplets

Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.

10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-19

2124 Molecular basis for plasma membrane recruitment of PI4KA by EFR3

Suresh, S.; Shaw, A. L.; Pemberton, J. G.; Scott, M. K.; Harris, N. J.; Parson, M. A.; Jenkins, M. L.; Rohilla, P.; Prats, A. A.; Balla, T.; Yip, C. K.; Burke, J. E.

10.1101/2024.04.30.587787 — biochemistry — Posted on 2024-07-19

2125 PLINDER: The protein-ligand interactions dataset and evaluation resource

Durairaj, J.; Adeshina, Y.; Cao, Z.; Zhang, X.; Oleinikovas, V.; Duignan, T.; McClure, Z.; Robin, X.; Studer, G.; Kovtun, D.; Rossi, E.; Zhou, G.; Veccham, S.; Isert, C.; Peng, Y.; Sundareson, P.; Akdel, M.; Corso, G.; Stärk, H.; Tauriello, G.; Carpenter, Z.; Bronstein, M.; Kucukbenli, E.; Schwede, T.; Naef, L.

10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-19

2126 Structure of Calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A

Shaw, A. L.; Suresh, S.; Parson, M. A.; Harris, N. J.; Jenkins, M. L.; Yip, C. K.; Burke, J. E.

10.1101/2024.04.09.588654 — biochemistry — Posted on 2024-07-19

2127 Within-species variation eclipses between-species differences in Pan consolation

Brooker, J. S.; Webb, C. E.; Kordon, S.; de Waal, F. B. M.; Clay, Z.

10.1101/2024.07.17.601006 — animal behavior and cognition — Posted on 2024-07-19

2128 Eyes on VR: Unpacking the Causal Chain Between Exposure, Reception, and Retention for Emotional Billboard Messages

Cho, H. J.; Lim, S.; Turner, M. M.; Bente, G.; Schmalzle, R.

10.1101/2024.07.19.604208 — animal behavior and cognition — Posted on 2024-07-19

2129 Diverse origins of near-identical antifreeze proteins in unrelated fish lineages provide insights into evolutionary mechanisms of new gene birth and protein sequence convergence

Rives, N.; Lamba, V.; Cheng, C.- H. C.; Zhuang, X.

10.1101/2024.03.12.584730 — evolutionary biology — Posted on 2024-07-19

2130 Testing the coordination hypothesis: incompatibilities in the absence of a single-cell bottleneck in an experimentally evolved social amoeba.

Jahan, I.; Scott, T. J.; Strassmann, J. E.; Queller, D. C.

10.1101/2024.05.12.593719 — evolutionary biology — Posted on 2024-07-19

2131 Forecasting dynamics of a recolonizing wolf population under different management strategies

Petracca, L. S.; Gardner, B.; Maletzke, B. T.; Converse, S. J.

10.1101/2023.03.23.534018 — ecology — Posted on 2024-07-19

2132 InsectChange: Comment

Gaume, L.; Desquilbet, M.

10.1101/2023.06.17.545310 — ecology — Posted on 2024-07-19

2133 The role of Imp and Syp RBPs in precise neuronal elimination by apoptosis through the regulation of TFs

GUAN, W.; NIE, Z.; Laurencon, A.; Bouchet, M.; Godin, C.; Kabir, C.; DARNAS, A.; Enriquez, J.

10.1101/2021.11.06.467542 — developmental biology — Posted on 2024-07-19

2134 Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

Lazzarin, E.; Gradisch, R.; Skopec, S. M.; Alves da Silva, L.; Sebastianelli-Schoditsch, C.; Szollosi, D.; Maier, J.; Sucic, S.; Roblek, M.; Kanner, B.; Sitte, H. H.; Stockner, T.

10.1101/2023.10.10.561652 — molecular biology — Posted on 2024-07-19

2135 Peptidoglycan-Chi3l1 interaction shapes gut microbiota in intestinal mucus layer

Chen, Y.; Yang, R.; Qi, B.; Shan, Z.

10.1101/2023.10.03.560754 — microbiology — Posted on 2024-07-19

2136 A conserved cell-pole determinant organizes proper polar flagellum formation

Arroyo-Perez, E. E.; Hook, J. C.; Alvarado, A.; Wimmi, S.; Glatter, T.; Thormann, K. M.; Ringgaard, S.

10.1101/2023.09.20.558563 — microbiology — Posted on 2024-07-19

2137 Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues

Glaser, A.; Chandrashekar, J.; Vasquez, J.; Arshadi, C.; Ouellette, N.; Jiang, X.; Baka, J.; Kovacs, G.; Woodard, M.; Seshamani, S.; Cao, K.; Clack, N.; Recknagel, A.; Grim, A.; Balaram, P.; Turschak, E.; Hooper, M.; Liddell, A.; Rohde, J.; Hellevik, A.; Takasaki, K.; Erion Barner, L.; Logsdon, M.; Chronopoulos, C.; de Vries, S.; Ting, J.; Perlmutter, S.; Kalmbach, B.; Dembrow, N.; Tasic, B.; Reid, R. C.; Feng, D.; Svoboda, K.

10.1101/2023.06.08.544277 — neuroscience — Posted on 2024-07-19

2138 High segregation and diminished global integration in large-scale brain functional networks enhances the perceptual binding of cross-modal stimuli

Singh, S. S.; Mukherjee, A.; Raghunathan, P.; Ray, D.; Banerjee, A.

10.1101/2020.09.02.276071 — neuroscience — Posted on 2024-07-19

2139 Genetic Foundations of Neurophysiological and Behavioural Variability Across the Lifespan

da Silva Castanheira, J.; Poli, J.; Hansen, J. Y.; Misic, B.; Baillet, S.

10.1101/2024.07.19.604292 — neuroscience — Posted on 2024-07-19

2140 Bacterial stress granule protects mRNA through ribonucleases exclusion

Pei, L.; Xian, Y.; Yan, X.; Schaefer, C.; Syeda, A. H.; Howard, J.; Liao, H.; Bai, F.; Leake, M. C.; Pu, Y.

10.1101/2024.04.27.591437 — biophysics — Posted on 2024-07-19

2141 TaxaNorm: a novel taxa-specific normalization approach for microbiome data

Wang, Z.; Lloyd, D.; Zhao, S.; Motsinger-Reif, A.

10.1101/2023.10.31.563648 — bioinformatics — Posted on 2024-07-19

2142 Human reproduction comes at the expense of faster aging and a shorter life

Hukkanen, M.; Kankaanpaa, A.; Heikkinen, A.; Kaprio, J.; Cristofari, R.; Ollikainen, M.

10.1101/2024.07.18.603826 — evolutionary biology — Posted on 2024-07-19

2143 MALDI-TOF MS profiling and its contribution to mosquito-borne diseases: a systematic review

Costa, M. d. M.; Corbel, V.; Ben Hamouda, R.; ALMERAS, L.

10.1101/2024.07.18.604078 — ecology — Posted on 2024-07-19

2144 Cryo-EM structure of the CBC-ALYREF complex

Clarke, B. P.; Angelos, A. E.; Mei, M.; Hill, P. S.; Xie, Y.; Ren, Y.

10.1101/2023.10.01.559959 — molecular biology — Posted on 2024-07-19

2145 Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis.

Wareing, N.; Mills, T. W.; Collum, S.; Wu, M.; Revercomb, L.; Girard, R.; Lyons, M.; Skaug, B.; Bi, W.; Ali, M. A.; Koochak, H.; Flores, A. R.; Yang, Y.; Zheng, W. J.; Swindell, W.; Assassi, S.; Karmouty-Quintana, H.

10.1101/2024.05.22.595271 — molecular biology — Posted on 2024-07-19

2146 Quantifiable Blood TCR Repertoire Components Associated with Immune Aging

Li, B.; Hu, J.; Pan, M.; Reid, B.; Tworoger, S.

10.1101/2024.07.19.604275 — immunology — Posted on 2024-07-19

2147 Systematic Analysis of Human Colorectal Cancer scRNA-seq Revealed Limited Pro-tumoral IL-17 Production Potential in Gamma Delta T Cells

Ran, R.; Trapecar, M.; Brubaker, D.

10.1101/2024.07.18.604156 — immunology — Posted on 2024-07-19

2148 Brain Structural Correlates of an Impending Initial Major Depressive Episode

Kraus, A.; Dohm, K.; Borgers, T.; Goltermann, J.; Grotegerd, D.; Winter, A.; Thiel, K.; Flinkenfluegel, K.; Schuermeyer, N.; Hahn, T.; Langer, S.; Kircher, T.; Nenadic, I.; Straube, B.; Jamalabadi, H.; Alexander, N.; Jansen, A.; Stein, F.; Brosch, K.; Usemann, P.; Teutenberg, L.; Thomas-Odenthal, F.; Meinert, S.; Dannlowski, U.

10.1101/2024.07.19.604266 — neuroscience — Posted on 2024-07-19

2149 Sensorimotor brain-computer interface performance depends on signal-to-noise ratio but not connectivity of the mu rhythm in a multiverse analysis of longitudinal data

Kapralov, N.; Jamshidi Idaji, M.; Stephani, T.; Studenova, A.; Vidaurre, C.; Ros, T.; Villringer, A.; Nikulin, V.

10.1101/2023.09.30.558407 — neuroscience — Posted on 2024-07-19

2150 Spatiotemporal resonance in mouse primary visual cortex

Gulbinaite, R.; Nazari, M.; Rule, M. E.; Bermudez Contreras, E. J.; Cohen, M. X.; Mohajerani, M. H.; Heimel, J. A.

10.1101/2023.07.31.551212 — neuroscience — Posted on 2024-07-19

2151 Engineered endosymbionts that modulate primary macrophage function and attenuate tumor growth by shifting the tumor microenvironment

Madsen, C. S.; Makela, A. V.; Maduka, C. V.; Greeson, E. M.; Tundo, A.; Ural, E.; Kulkarni, S. H.; Zarea, A.; Kiupel, M.; Sayadi, M.; Contag, C. H.

10.1101/2024.07.18.604190 — synthetic biology — Posted on 2024-07-19

2152 Unveiling Frailty: Comprehensive and Sex-Specific Characterization in Prematurely Aging PolgA Mice

Yilmaz, D.; Singh, A.; Wehrle, E.; Kuhn, G. A.; Mathavan, N.; Mueller, R.

10.1101/2024.02.15.580562 — physiology — Posted on 2024-07-19

2153 Comprehensive Analysis of Exportins Expression and its Prognostic Significance in Colon Adenocarcinoma: Insights from Public Databases

Kalia, P.; Nair, R. R.; Yadav, S. S.

10.1101/2024.07.18.604060 — cancer biology — Posted on 2024-07-19

2154 PRECLINICAL DEVELOPMENT OF A ROMIDEPSIN NANOPARTICLE DEMONSTRATES SUPERIOR TOLERABILITY AND EFFICACY IN MODELS OF HUMAN T-CELL LYMPHOMA AND LARGE GRANULAR LYMPHOCYTE LEUKEMIA

Pal, I.; Illendula, A.; Joyner, A.; Manavalan, J. S.; Deddens, T. M.; Sabzevari, A.; Damera, D. P.; Zuberi, S.; Marchi, E.; Fox, T. E.; Dunlap-Brown, M. E.; Jayappa, K. D.; Craig, J. W.; Loughran, T. P.; Feith, D. J.; O'Connor, O. A.

10.1101/2024.07.18.603379 — cancer biology — Posted on 2024-07-19

2155 Analysis of iPLA2-VIA Gene Expression in The CNS of Larvae and Adult Drosophila Melanogaster Flies

Moura, G.

10.1101/2024.07.17.603941 — bioinformatics — Posted on 2024-07-19

2156 Cost-effective DNA storage with DNA movable type

Wang, C.; Wei, D.; Wei, Z.; Yang, D.; Xing, J.; Wang, Y.; Wang, X.; Wang, P.; Ma, G.; Zhang, X.; Li, H.; Tang, C.; Hou, P.; Wang, J.; Gao, R.; Xie, G.; Li, C.; Ju, Y.; Wang, P.; Yue, L.; Zhao, Y.; Sheng, Y.; Xiao, J.; Niu, H.; Xu, S.; Duan, B.; Bu, D.; Tan, G.; Chen, F.

10.1101/2024.07.17.603163 — bioinformatics — Posted on 2024-07-19

2157 From spreadsheet lab data templates to knowledge graphs: A FAIR data journey in the domain of AMR research

Gadiya, Y.; Abbassi-Daloii, T.; Ioannidis, V.; Juty, N.; Stie Kallesoe, C.; Attwood, M.; Kohler, M.; Gribbon, P.; Witt, G.

10.1101/2024.07.18.604030 — bioinformatics — Posted on 2024-07-19

2158 MLSPred-Bench: ML-Ready Benchmark LeveragingSeizure Detection EEG data for Predictive Models

Mohammad, U.; Saeed, F.

10.1101/2024.07.17.604006 — bioinformatics — Posted on 2024-07-19

2159 Shape that matters: Yolk geometry spatially modulates developing vascular networks within chick chorioallantoic membrane

Padmanaban, P.; Wanders, D.; Katovich, O. K.; Salehi-Nik, N.; Levenberg, S.; Rouwkema, J.

10.1101/2024.07.18.604146 — bioengineering — Posted on 2024-07-19

2160 Core Tri-fucosylation of Nematode N-glycans Requires Golgi α-mannosidase III Activity that Impacts Animal Growth and Behaviours

Kendler, J.; Woels, F.; Thapliyal, S.; Arcalis, E.; Gabriel, H.; Kubitschek, S.; Malzl, D.; Strobl, M. R.; Palmberger, D.; Luber, T.; Unverzagt, C.; Paschinger, K.; Glauser, D. A.; Wilson, I. B. H.; Yan, S.

10.1101/2024.07.18.600072 — biochemistry — Posted on 2024-07-19

2161 UK mosquitoes are competent to transmit Usutu virus at native temperatures

Pilgrim, J. D.; Metelmann, S.; Widlake, E.; Seechurn, N.; Vaux, A.; Mansfield, K. L.; Tanianis-Hughes, J.; Sherlock, K.; Johnson, N.; Medlock, J.; Baylis, M.; Blagrove, M. S.

10.1101/2024.07.19.604126 — ecology — Posted on 2024-07-19

2162 HIF1A contributes to the survival of aneuploid and mosaic pre-implantation embryos

Sanchez-Vasquez, E.; Zernicka-Goetz, M.; Bronner, M.

10.1101/2023.09.04.556218 — developmental biology — Posted on 2024-07-19

2163 An Omni-Mesoscope for multiscale high-throughput quantitative phase imaging of cellular dynamics and high-content molecular characterization

Ma, H.; Chen, M.; Xu, J.; Zhao, Y.; Liu, Y.

10.1101/2024.07.18.604137 — cell biology — Posted on 2024-07-19

2164 The Evolution and Epidemiology of H3N2 Canine Influenza Virus After 20 Years in Dogs

Wasik, B. R.; Damodaran, L.; Maltepes, M. A.; Voorhees, I. E.; Leutenegger, C. M.; Newbury, S.; Moncla, L. H.; Dalziel, B. D.; Goodman, L. B.; Parrish, C. R.

10.1101/2024.07.19.604289 — microbiology — Posted on 2024-07-19

2165 Auditory-motor entrainment and listening experience shape the perceptual learning of concurrent speech

MacLean, J.; Stirn, J.; Bidelman, G.

10.1101/2024.07.18.604167 — neuroscience — Posted on 2024-07-19

2166 Altered Cortical Network Dynamics during Observing and Preparing Action in Patients with Corticobasal Syndrome

Kroesche, M.; Hartmann, C.; Butz, M.; Schnitzler, A.; Hirschmann, J.

10.1101/2024.07.19.604284 — neuroscience — Posted on 2024-07-19

2167 Happiness promotes global processing in haptic perception

Cavdan, M.; Kapucu, A.; Doerschner, K.; Drewing, K.

10.1101/2024.07.15.603491 — neuroscience — Posted on 2024-07-19

2168 Temporal dynamics analysis reveals that concurrent working memory load eliminates the Stroop effect through disrupting stimulus-response mapping

Li, Y.; Lin, Y.; Li, Q.; Chen, Y.; Li, Z.; Chen, A.

10.1101/2024.07.17.603992 — neuroscience — Posted on 2024-07-19

2169 Odor source distance is predictable from a time-history of odor statistics for large scale outdoor plumes

Nag, A.; van Breugel, F.

10.1101/2023.07.20.549973 — ecology — Posted on 2024-07-19

2170 Multipath projection stereolithography (MPS) for 3D printing microfluidic devices

Soman, P.; Xiong, Z.; Geffert, Z. J.; Grutzmacher, J.; Wilderman, M.; Mohammadi, A.; Filip, A.; Li, Z.

10.1101/2024.07.18.604144 — bioinformatics — Posted on 2024-07-19

2171 Sodium butyrate is incorporated into central metabolism in fly head while inducing oxygen consumption increase

Müller-Eigner, A.; Gille, B.; Dethloff, F.; Meng, C.; Ludwig, C.; Heiker, J. T.; Giavalisco, P.; Peleg, S.

10.1101/2024.07.18.604059 — biochemistry — Posted on 2024-07-19

2172 Tbx1 stabilizes differentiation of the cardiopharyngeal mesoderm and drives morphogenesis in the pharyngeal apparatus

Lanzetta, O.; Bilio, M.; Liebig, J.; Jechow, K.; Ten, F. W.; Ferrentino, R.; Aurigemma, I.; Illingworth, E.; Conrad, C.; Lukassen, S.; Angelini, C.; Baldini, A.

10.1101/2024.07.16.603669 — developmental biology — Posted on 2024-07-19

2173 Permissive and instructive Hox codes govern limb positioning

Wang, Y.; Hintze, M.; Wang, J.; Petzsch, P.; Kohrer, K.; Tao, H.; Cheng, L.; Zhou, P.; Wang, J.; Liao, Z.; Qi, X.-F.; Cai, D.; Bartolomaeus, T.; Schilling, K.; Wilting, J.; Kuerten, S.; Koentges, G.; Patel, K.; Pu, Q.; Huang, R.

10.1101/2024.07.15.603511 — developmental biology — Posted on 2024-07-19

2174 Targeting IRE1α improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in obesity

Wu, D.; Eeda, V.; Maria, Z.; Rawal, K.; Herlea-Pana, O.; Babu Undi, R.; Lim, H.-Y.; Wang, W.

10.1101/2024.07.17.603931 — cell biology — Posted on 2024-07-19

2175 Endothelial cell dysfunction and retinal arteriolar narrowing in young adults with elevated blood pressure

Tan, C.; Lewandowski, A. J.; Hanssen, H.; Streese, L.; Huckstep, O.; Fischer, R.; Alsharqi, M.; Mohamed, A.; Williamson, W.; Leeson, P.; Bertagnolli, M.

10.1101/2024.07.12.603349 — cell biology — Posted on 2024-07-19

2176 PPR767 affects plant architecture and drought resistance by modulating complex I activity and ROS content in rice

Peng, L.; Xiao, H.; Xu, Y.; Huang, Z.; Yang, X.; Lv, C.; Huang, L.; Hu, J.

10.1101/2024.07.17.603968 — molecular biology — Posted on 2024-07-19

2177 Incidence and multidrug resistance of Escherichia coli pathotypes on fresh vegetables and salads.

VAZQUEZ-QUINONES, C. R.; Rincon Guevara, M. A.; Natividad-Bonifacio, I.; Vazquez-Salinas, C.; Gonzalez-Marquez, H.

10.1101/2024.07.18.604175 — microbiology — Posted on 2024-07-19

2178 Ecotype-specific genomic features within the Escherichia cryptic clade IV

Saraceno, M.; Frankel, N.; Graziano, M.

10.1101/2024.07.17.603965 — microbiology — Posted on 2024-07-19

2179 Antibacterial activity of tamoxifen derivatives against methicillin-resistant Staphylococcus aureus

Molina Panadero, I.; Falcon Torres, J.; Hmadcha, A.; Princiotto, S.; Cutarella, L.; Mori, M.; Dallavalle, S.; Christodoulou, M.; Smani, Y.

10.1101/2024.07.16.603795 — microbiology — Posted on 2024-07-19

2180 Antiparasitic effect of peptoids against Cryptosporidium parvum

Lamont, B.; Russell, B. M.; Suwanarusk, R.; Nielsen, J. E.; Sorensen, K.; Yung, D.; Barron, A.; Pletzer, D.; Muhsin-Sharafaldine, M.-R.

10.1101/2024.07.16.603782 — microbiology — Posted on 2024-07-19

2181 PicoCam: High-resolution 3D imaging of live animals and preserved specimens

Medina, J.; Irschick, D.; Epperly, K.; Cuban, D.; Elting, R.; Mansfield, L.; Lee, N.; Fermandes, A. M.; Garzon-Agudelo, F.; Rico-Guevara, A.

10.1101/2024.07.16.603742 — evolutionary biology — Posted on 2024-07-19

2182 An efficient algorithm for microtubule-based nucleation reveals large sensitivity to cell geometry of the plant cortical array

Saltini, M.; Deinum, E. E.

10.1101/2024.03.25.586463 — biophysics — Posted on 2024-07-19

2183 TRGT-denovo: accurate detection of de novo tandem repeat mutations

Mokveld, T.; Dolzhenko, E.; Dashnow, H.; Nicholas, T. J.; Sasani, T.; van der Sanden, B.; Jadhav, B.; Pedersen, B.; Kronenberg, Z.; Tucci, A.; Sharp, A. J.; Quinlan, A. R.; Gilissen, C.; Hoischen, A.; Eberle, M. A.

10.1101/2024.07.16.600745 — bioinformatics — Posted on 2024-07-19

2184 Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow

Gerlevik, S.; Seymen, N.; Hama, S.; Mumtaz, W.; Thompson, I. R.; Jalili, S. R.; Kaya, D. E.; Iacoangeli, A.; Pellagatti, A.; Boultwood, J.; Napolitani, G.; Mufti, G. J.; Karimi, M. M.

10.1101/2024.03.11.584361 — genomics — Posted on 2024-07-19

2185 The complete mitogenome of an unidentified Oikopleura species

Wibisana, J. N.; Plessy, C.; Dierckxsens, N.; Masunaga, A.; Miao, J.; Luscombe, N.

10.1101/2024.07.04.602139 — genomics — Posted on 2024-07-19

2186 An essential role for RNA binding by Periphilin in silencing by the HUSH complex

Lehner, P. J.; Wit, N.; Bloor, S.

10.1101/2024.07.17.602677 — genetics — Posted on 2024-07-19

2187 Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis Thaliana populations

Gibbs, P.; Paril, J.; Fournier-Level, A.

10.1101/2024.07.09.601435 — genetics — Posted on 2024-07-19

2188 WHO WINS? COMPARISON BETWEEN EMERGENT MACROPHYTES AND PONTEDERIA CRASSIPES (WATER HYACINTH) AS NATURE-BASED SOLUTIONS FOR NUTRIENT PHYTOREMEDIATION AND CYANOBACTERIA MITIGATION

Filho, C. M.; Santos, A. A.; Lima, D.; Silva, L. d. O.; Pacheco, A. B. F.; Azevedo, S. M. F. d. O. e.

10.1101/2024.07.16.603719 — ecology — Posted on 2024-07-19

2189 Neuropeptide Bursicon and its receptor mediated the transition from summer-form to winter-form of Cacopsylla chinensis

Zhang, Z.; Li, J.; Wang, Y.; Li, Z.; Liu, X.; Zhang, S.

10.1101/2024.04.06.588405 — ecology — Posted on 2024-07-19

2190 Claudin-11 regulates immunological barrier formation and spermatogonial proliferation through stem cell factor

Sugawara, T.; Sonoda, K.; Chompusri, N.; Noguchi, K.; Okada, S.; Furuse, M.; Wakayama, T.

10.1101/2024.07.16.602181 — developmental biology — Posted on 2024-07-19

2191 NR2F2 is required in the embryonic testis for Fetal Leydig Cell development

Perea-Gomez, A.; Bellido Carreras, N.; Dhellemmes, M.; Tang, F.; Le Gallo, C.; Chaboissier, M.-C.

10.1101/2024.07.17.602099 — developmental biology — Posted on 2024-07-19

2192 Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import

Chang, Y.-T.; Barad, B. A.; Rahmani, H.; Zid, B. M.; Grotjahn, D. A.

10.1101/2024.07.17.604013 — cell biology — Posted on 2024-07-19

2193 Distinct tissue-niche localization and function of synovial tissue myeloid DC subsets in health, and in active and remission Rheumatoid Arthritis

MacDonald, L.; Elmesmari, A.; Somma, D.; Frew, J.; Di Mario, C.; Madhu, R.; Paoletti, A.; Simakou, T.; Hardy, O. M.; Tolusso, B.; Campobasso, D.; Perniola, S.; Gessi, M.; Gigante, M. R.; Petricca, L.; Bruno, D.; Coletto, L. A.; Benvenuto, R.; Isaacs, J. D.; Filby, A.; McDonald, D.; Sim, J. P. X.; Jamieson, N.; D'Agostino, M. A.; Wei, K.; Millar, N. L.; Milling, S.; McSharry, C.; Gremese, E.; Affleck, K.; Baker, K. F.; McInnes, I. B.; Otto, T. D.; Korsunsky, I.; Alivernini, S.; Kurowska-Stolarska, M.

10.1101/2024.07.17.600758 — immunology — Posted on 2024-07-19

2194 Characterizing the Spatial Distribution of Dendritic RNA at Single Molecule Resolution

Kim, J.; Rosario, J.; Mendoza, E.; Kuang, D.; Kim, J.

10.1101/2024.07.18.602927 — neuroscience — Posted on 2024-07-19

2195 A ternary Neurexin-T178-PTPR complex represents a core-module of neuronal synapse organization

Thivaios, S.; Schwenk, J.; Brechet, A.; Boudkkazi, S.; Henneken, P.; Kocylowski, M. K.; Haupt, A.; Kaminski, D.; van den Broucke, J.-B.; Schreiner, D.; Schulte, U.; Sterky, F. H.; Yuzaki, M.; Scheiffele, P.; Fakler, B.

10.1101/2024.07.16.603715 — neuroscience — Posted on 2024-07-19

2196 The promise and peril of comparing fluorescence lifetime in biology revealed by simulations

Ma, P.; Sternson, S.; Chen, Y.

10.1101/2023.12.20.572686 — neuroscience — Posted on 2024-07-19

2197 Analysis of the Modulation of RAF Signaling by 14-3-3 Proteins

Carlip, P.; Stites, E. C.

10.1101/2024.07.16.603736 — systems biology — Posted on 2024-07-19

2198 Genetic variation in the species Arabidopsis thaliana reveals the existence of natural heat resilience factors for meiosis

Zhao, J.; Fu, H.; Wang, Z.; Zhang, M.; Liang, Y.; Cui, X.; Pan, W.; Ren, Z.; Wu, Z.; Zhang, Y.; Gui, X.; Huo, L.; Lei, X.; Wang, C.; Schnittger, A.; Pawlowski, W. P.; Liu, B.

10.1101/2024.07.16.603532 — plant biology — Posted on 2024-07-19

2199 Pectin methylesterase activity is required for RALF1 peptide signalling output

Roessling, A.-K.; Dunser, K.; Liu, C.; Lauw, S.; Rodriguez- Franco, M.; Kalmbach, L.; Barbez, E.; Kleine-Vehn, J.

10.1101/2023.08.18.553913 — plant biology — Posted on 2024-07-19

2200 Untargeted metabolomics reveals anion and organ-specific biochemistry of salinity tolerance in willow

Sas, E.; Fremont, A.; Gonzalez, E. J. B.; Sarrazin, M.; Barnabe, S.; Labrecque, M.; Brereton, n. J. B.; Pitre, F. E.

10.1101/2024.07.16.603755 — plant biology — Posted on 2024-07-19

2201 The microRNA156/SPL9 module mediates auxin response to facilitate apical hook maintenance in Arabidopsis

Pierdona, F. G.; Silva, A. J. M.; Vicente, M. H.; Taylor, L.; Pedmale, U. V.; Nogueira, F. T. S.

10.1101/2024.07.16.603710 — plant biology — Posted on 2024-07-19

2202 Mapping Genetic Interactions of All Paralogs in the Human Genome

Flister, M. J.; Verduzco, D.; Petiwala, S.; Ghekas, C.; Shi, X.; Lu, C.; Dezso, Z. J.

10.1101/2024.07.16.603642 — cancer biology — Posted on 2024-07-19

2203 Multiple allostery in the regulation of PDGFR beta kinase activities

Zhang, Y.; Wang, M.; Shao, G.; Shang, Q.; Dong, M.-Q.; Qin, X.; Mi, L.-Z.

10.1101/2024.06.06.597829 — biophysics — Posted on 2024-07-19

2204 AI-predicted protein deformation encodes energy landscape perturbation

McBride, J. M.; Tlusty, T.

10.1101/2023.10.12.561990 — biophysics — Posted on 2024-07-19

2205 SIngle cell level Genotyping Using scRna Data (SIGURD)

Grasshoff, M.; Kalmer, M.; Chaitan, N.; Kricheldorf, K.; Maurer, A.; Weiskirchen, R.; Koschmieder, S.; Costa, I. G.

10.1101/2024.07.16.603737 — bioinformatics — Posted on 2024-07-19

2206 Genomics-FM: Universal Foundation Model for Versatile andData-Efficient Functional Genomic Analysis

Ye, P.; Bai, W.; Ren, Y.; Li, W.; Qiao, L.; Liang, C.; Wang, L.; Cai, Y.; Sun, J.; Yang, Z.; Zheng, P.; Dong, N.; Chen, T.; Wang, Z.; Liu, X.; Ma, X.; Yan, H.; Wang, Z.; Wang, S.; Ouyang, W.

10.1101/2024.07.16.603653 — bioinformatics — Posted on 2024-07-19

2207 PROTEORIZER: A holistic approach to untangle functional consequences of variants of unknown significance.

Schmenger, T.; Diwan, G.; Russell, R. B.

10.1101/2024.07.16.603688 — bioinformatics — Posted on 2024-07-19

2208 Within-species variation eclipses between-species differences in Pan consolation

Brooker, J. S.; Webb, C. E.; Kordon, S.; de Waal, F. B. M.; Clay, Z.

10.1101/2024.07.17.601006 — animal behavior and cognition — Posted on 2024-07-19

2209 Potent pollen gene regulation by DNA glycosylases in maize

Zeng, Y.; Somers, J.; Bell, H. S.; Vejlupkova, Z.; Dawe, R. K.; Fowler, J. E.; Nelms, B.; Gent, J. I.

10.1101/2024.02.13.580204 — genetics — Posted on 2024-07-19

2210 Wheat TaNADPO promotes spot blotch resistance

Yuan, M.; Zeng, Q.; Hua, L.; Wu, J.; Zhao, S.; Li, M.; Ren, X.; Su, J.; Ren, Z.; Ma, L.; Liu, Z.; Wang, K.; Sun, M.; Yan, H.; Kang, Z.; Han, D.; Chen, S.; Wang, X.

10.1101/2024.07.16.602850 — genetics — Posted on 2024-07-19

2211 Extensive transcriptional differentiation and specialization of a parasite across its host's metamorphosis

DuBose, J. G.; de Roode, J. C.

10.1101/2024.07.16.603694 — evolutionary biology — Posted on 2024-07-19

2212 Experimental evolution of gene essentiality in bacteria

Bao, L.; Zhu, Z.; Ismail, A.; Zhu, B.; Anandan, V.; Whiteley, M.; Kitten, T.; Xu, P.

10.1101/2024.07.16.600122 — evolutionary biology — Posted on 2024-07-19

2213 Gene expression responses to environmental cues shed light on components of the migratory syndrome in butterflies

Shipilina, D.; Höök, L.; Näsvall, K.; Talla, V.; Palahi, A.; Parkes, E.; Vila, R.; Talavera, G.; Backström, N.

10.1101/2024.07.17.602486 — evolutionary biology — Posted on 2024-07-19

2214 Genomic data reveals habitat partitioning in massive Porites on Guam, Micronesia

Combosch, D.; Lemer, S.; Burdick, D.; Forsman, Z.; Primov, K. D.

10.1101/2024.07.16.603743 — evolutionary biology — Posted on 2024-07-19

2215 Interaction range of common goods shapes Black Queen dynamics beyond the cheater-cooperator narrative

Fullmer, M. S.; van Dijk, B.; Takeuchi, N.

10.1101/2024.07.16.603646 — evolutionary biology — Posted on 2024-07-19

2216 Climate-driven vegetation characteristics shape phytophagous and carnivorous insect diversity in South African savannahs

Gaona, F. P.; Delabye, S.; Potocky, P.; Govorov, V.; Cuda, J.; Foxcroft, L. C.; Garlacz, R.; Hejda, M.; MacFadyen, S.; Pyrcz, T.; Pyskova, K.; Sedlacek, O.; Storch, D.; Pysek, P.; Tropek, R.

10.1101/2024.07.16.603689 — ecology — Posted on 2024-07-19

2217 Analysis of mixtures of birds and insects in weather radar data

Shi, X.; Drucker, J.; Chapman, J.; Sanchez-Herrera, M.; Dokter, A. M.

10.1101/2024.07.17.601450 — ecology — Posted on 2024-07-19

2218 Trap Spacing Protocols for Amazonian Dung Beetle Surveys

Hernandez Perez, E.; Aycart, P.; Chaboteaux, E.; Lopera Toro, A.; Forsyth, A.

10.1101/2024.07.16.603696 — ecology — Posted on 2024-07-19

2219 Oral citrate supplementation mitigates age-associated pathological intervertebral disc calcification in LG/J mice

Ottone, O. K.; Mundo, J. J.; Kwakye, B. N.; Slaweski, A.; John, J. A.; Wu, Q.; Connelly, M. A.; Niaziorimi, F.; van de Wetering, K.; Risbud, M.

10.1101/2024.07.17.604008 — cell biology — Posted on 2024-07-19

2220 Multiple clustered centrosomes in antigen-presenting cells foster T cell activation without MTOC polarization

Stoetzel, I.; Weier, A.-K.; Sarkar, A.; Som, S.; Konopka, P.; Mikova, E.; Boethling, J.; Homrich, M.; Schaedel, L.; Kazmaier, U.; Symeonidis, K.; Abdullah, Z.; Uderhardt, S.; Hons, M.; Paul, R.; Rieger, H.; Kiermaier, E.

10.1101/2024.07.18.604057 — cell biology — Posted on 2024-07-19

2221 Alternative splicing in mechanically stretched podocytes as a model of glomerular hypertension

Mattias, F.; Tsoy, O.; Hammer, E.; Gress, A.; Simm, S.; Lio, C. T.; Ameling, S.; Kalinina, O.; Amann, K.; Dreher, L.; Wenzel, U.; Endlich, K.; Baumbach, J.; Voelker, U.; Endlich, N.; Kliewe, F.

10.1101/2024.07.17.603550 — cell biology — Posted on 2024-07-19

2222 STANDARDISED FLOW CYTOMETRIC PROCEDURE FOR DEEP CHARACTERIZATION OF NANOPARTICLES

Tirelli, V.; Grasso, F.; Barreca, V.; Polignano, D.; gallinaro, a.; Cara, A.; Sargiacomo, M.; Fiani, M. L.; Sanchez, M.

10.1101/2024.07.18.604065 — cell biology — Posted on 2024-07-19

2223 Significantly reduced, but balanced, rates of mitochondrial fission and fusion are sufficient to maintain the integrity of yeast mitochondrial DNA

Wisniewski, B. T.; Lackner, L. L.

10.1101/2024.07.18.604121 — cell biology — Posted on 2024-07-19

2224 Endomucin regulates the endothelial cytoskeleton independent of VEGF

Moon, J.; Chaudhary, S.; Rodriguez Martinez, L.; Hu, Z.; D'Amore, P. A.

10.1101/2024.07.17.603969 — cell biology — Posted on 2024-07-19

2225 Dachsous is a key player in epithelial wound closure by modulating cell shape changes and cytoskeleton dynamics

Porfirio-Rodrigues, P.; Pereira, T.; Jacinto, A.; Carvalho, L.

10.1101/2024.07.17.603948 — cell biology — Posted on 2024-07-19

2226 Identification of stable reference genes for quantitative real-time PCR in human fibroblasts from lymph nodes and synovium

Rasouli, S.; van Ansenwoude, C.; Semmelink, J. F.; van Baarsen, L. G.; de Jong, T. A.

10.1101/2024.07.12.603332 — molecular biology — Posted on 2024-07-19

2227 Genes in Humans and Mice: Insights from Deep learning of 777K Bulk Transcriptomes

Su, Z.; Fang, M.; Smolnikov, A.; Vafaee, F.; Dinger, M. E.; Oates, E.

10.1101/2024.04.01.587517 — bioinformatics — Posted on 2024-07-19

2228 Mammalian D-Cysteine controls insulin secretion in the pancreas

Roychaudhuri, R.; West, T.; Bhattacharya, S.; Saavedra, H.; Albacarys, L.; Gadalla, M. M.; Amzel, L. M.; Yang, P.; Snyder, S. H.

10.1101/2022.05.17.492243 — biochemistry — Posted on 2024-07-19

2229 PLINDER: The protein-ligand interactions dataset and evaluation resource

Durairaj, J.; Adeshina, Y.; Cao, Z.; Zhang, X.; Oleinikovas, V.; Duignan, T.; McClure, Z.; Robin, X.; Kovtun, D.; Rossi, E.; Zhou, G.; Veccham, S.; Isert, C.; Peng, Y.; Sundareson, P.; Akdel, M.; Corso, G.; Stärk, H.; Carpenter, Z.; Bronstein, M.; Kucukbenli, E.; Schwede, T.; Naef, L.

10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-19

2230 Increased offspring size and accelerated gestation in a temperate ectothermic vertebrate under temperatures predicted by a worst-case climate change model

Hubert, D. L.; Bentz, E. J.; Mason, R. T.

10.1101/2023.11.25.568677 — ecology — Posted on 2024-07-19

2231 The chemopreventive effects of Curcumin against oxidative stress induced by Cadmium or H2O2 are mediated by Nrf2/ARE signaling and protective autophagy in myeloid cells

Russo, M.; Di Giacomo, A.; Fiore, F.; Spagnuolo, C.; Carbone, V.; Minasi, P.; Russo, G. L.

10.1101/2024.07.17.603853 — cell biology — Posted on 2024-07-19

2232 Reprograming gene expression in hibernating C. elegans involves the IRE-1/XBP-1 pathway

Engelfriet, M. L.; Guo, Y.; Arnold, A.; Valen, E.; Ciosk, R.

10.1101/2024.07.16.603818 — cell biology — Posted on 2024-07-19

2233 Bacterial Protein Signatures Identified in Porphyromonas gingivalis Containing-Autophagic Vacuoles Reveal Co-Evolution Between Oral Red/Orange Complex Bacteria and Gut Bacteria

Paul, A.; Wellslager, B.; Williamson, M.; Yilmaz, O.

10.1101/2024.07.11.602567 — microbiology — Posted on 2024-07-19

2234 Establishing a Male-Positive Genetic Sexing Strain in the Asian Malaria Vector Anopheles stephensi

Weng, S.-C.; Chen, F.; Li, M.; Lee, S.; Gerry, C.; Turksoy, D. C.; Akbari, O. S.

10.1101/2024.07.17.603997 — bioengineering — Posted on 2024-07-18

2235 High-motility pro-tumorigenic monocytes drive macrophage enrichment in the tumor microenvironment

Du, W.; Zhou, B.; Forjaz, A.; Shin, S. M.; Wu, F.; Crawford, A. J.; Nair, P. R.; Johnston, A. C.; West-Foyle, H.; Tang, A.; Kim, D.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Phillip, J. M.; Ho, W. J.; Sanin, D. E.; Wirtz, D.

10.1101/2024.07.16.603739 — immunology — Posted on 2024-07-18

2236 Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons

Brahmia, B.; Naaldijk, Y.; Sarkar, P.; Parisiadou, L.; Hilfiker, S.

10.1101/2024.07.16.603799 — neuroscience — Posted on 2024-07-18

2237 Stepping dynamics of dynein characterized by MINFLUX

Slivka, J.; Gleave, E.; Wijewardena, D. P.; Canty, J. T.; Selvin, P. R.; Carter, A. P.; Yildiz, A.

10.1101/2024.07.16.603667 — biophysics — Posted on 2024-07-18

2238 A Cost-effective, High-throughput, Highly Accurate Genotyping Method for Outbred Populations

Chen, D.; Chitre, A. S.; Nguyen, K.-M. H.; Cohen, K. A.; Peng, B. F.; Ziegler, K. S.; Okamoto, F.; Lin, B.; Johnson, B. B.; Sanches, T. M.; Cheng, R.; Polesskaya, O.; Palmer, A. A.

10.1101/2024.07.17.603984 — genetics — Posted on 2024-07-18

2239 Beta3 accelerates microtubule plus end maturation through a divergent lateral interface

Wood, L. M.; Moore, J.

10.1101/2024.07.17.603993 — cell biology — Posted on 2024-07-18

2240 Induced degradation of SNAP-fusion proteins

Abraham Pol, S.; Liljenberg, S.; Barr, J.; Simon, G.; Wong-Dilworth, L.; Paterson, D. L.; Berishvili, V. P.; Bottanelli, F.; Kaschani, F.; Kaiser, M.; Pettersson, M.; Hellerschmied, D.

10.1101/2024.07.18.603056 — cell biology — Posted on 2024-07-18

2241 A Field-Deployable Arsenic Sensor Integrating Bacillus Megaterium with CMOS Technology

Hu, C. Y.; McManus, J. B.; Aghlmand, F.; Larsson, E. M.; Emami, A.; Murray, R. M.

10.1101/2024.07.18.604150 — synthetic biology — Posted on 2024-07-18

2242 Unraveling Structural Disparities in Human and Mycobacterium Tuberculosis Type-I Fatty Acid Synthase

Kumar, A.; Rama, P.; Katkar, H. H.

10.1101/2024.07.17.603935 — biophysics — Posted on 2024-07-18

2243 Microbial metabolomics' latest SICRIT: Soft ionization by Chemical Reaction in-Transfer mass spectrometry

McAtamney, A.; Ferranti, A.; Ludvik, D. A.; Yildiz, F. H.; Mandel, M. J.; Hayward, T.; Sanchez, L.

10.1101/2024.07.17.604007 — biochemistry — Posted on 2024-07-18

2244 Structure of yeast RAVE bound to a partial V1 complex

Wang, H.; Tarsio, M.; Kane, P. M.; Rubinstein, J. L.

10.1101/2024.07.18.604153 — biochemistry — Posted on 2024-07-18

2245 STK19 is a transcription-coupled repair factor that participates in UVSSA ubiquitination and TFIIH loading.

Hu, J.; Tan, Y.

10.1101/2024.07.17.604011 — biochemistry — Posted on 2024-07-18

2246 CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.

Ackloo, S.; Arrowsmith, C. H.; Ban, F.; Barden, C. J.; Beck, H.; Beranek, J.; Berenger, F.; Bolotokova, A.; Bret, G.; Breznik, M.; Carosati, E.; Chau, I.; Chen, Y.; Cherkasov, A.; Della Corte, D.; Denzinger, K.; Dong, A.; Draga, S.; Dunn, I.; Edfeldt, K.; Edwards, A.; Eguida, M.; Eisenhuth, P.; Friedrich, L.; Fuerll, A.; Gardiner, S.; Gentile, F.; Ghiabi, P.; Gibson, E.; Glavatskikh, M.; Gorgulla, C.; Guenther, J.; Gunnarsson, A.; Guseve, F.; Gutkin, E.; Hillisch, A.; Hoffer, L.; Hogner, A.; Irwin, J. J.; Isayev, O.; Ivanova, A.; Jacquemard, C.; Jarrett, A. J.; Jensen, J. H.; Kireev, D.; Klebe

10.1101/2024.07.18.603797 — biochemistry — Posted on 2024-07-18

2247 Interplay of Anchor and Latch Residues at Enzyme Active Site in Preserving Induced Fit Configurations for Efficient Catalysis: A Case Study of CARNMT1 for Histidine Methylation

Guo, H.; Qian, P.; Deng, H.; Rahman, A.

10.1101/2024.07.18.604158 — biochemistry — Posted on 2024-07-18

2248 Structural basis for the interaction between the bacterial cell division proteins FtsZ and ZapA

Fujita, J.; Hibino, K.; Kagoshima, G.; Kamimura, N.; Kato, Y.; Uehara, R.; Namba, K.; Uchihashi, T.; Matsumura, H.

10.1101/2024.07.18.604045 — molecular biology — Posted on 2024-07-18

2249 Histone Tetrasome Dynamics Affects Chromatin Transcription

Shi, X.; Fedulova, A.; Kotova, E.; Maluchenko, N.; Armeev, G.; Chen, Q.; Prasanna, C.; Sivkina, A.; Feofanov, A.; Kirpichnikov, M.; Nordenskiold, L.; Shaytan, A. K.; Studitsky, V.

10.1101/2024.07.18.604164 — molecular biology — Posted on 2024-07-18

2250 Sensitive detection and propagation of brain-derived tau assemblies in HEK293 based wild-type tau seeding assays

Huang, M.; McEwan, W. A.

10.1101/2024.07.18.604077 — molecular biology — Posted on 2024-07-18

2251 DArTSNPbased genetic diversity analyses in cassava (Manihot esculenta) genotypes sourced from different regions revealed high level of diversity within population

Abadura, N. S.; A, A. T.; Y., I. R.; Beyene, T. M.; Abtew, W. G.

10.1101/2024.07.18.604086 — molecular biology — Posted on 2024-07-18

2252 FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites

Antonicka, H.; Weraarpachai, W.; Vuckovic, A.; Hillen, H. S.; Shoubridge, E. A.

10.1101/2024.07.18.603998 — molecular biology — Posted on 2024-07-18

2253 A development-specific POLX essential for programmed genome rearrangement in Paramecium tetraurelia

Verron, B.; Arnaiz, O.; Zangarelli, C.; Mathy, N.; Betermier, M.; BISCHEROUR, J.

10.1101/2024.07.18.604053 — molecular biology — Posted on 2024-07-18

2254 Stabilized dengue virus 2 envelope subunit vaccine redirects the neutralizing antibody response to all E-domains

Thiono, D. J.; Samaras, D. L.; Phan, T.; Zhu, D. R.; Shah, R. P.; Castillo, I. N.; Forsberg, L. J.; Premkumar, L.; Baric, R. S.; Tian, S.; Kuhlman, B.; de Silva, A. M.

10.1101/2024.07.18.604114 — microbiology — Posted on 2024-07-18

2255 A conjugative plasmid exploits flagella rotation as a cue to facilitate its transfer

Bhattacharya, S.; Bejerano-Sagie, M.; Ravins, M.; Zeroni, L.; Kaur, P.; Gopu, V.; Rosenshine, I.; Ben-Yehuda, S.

10.1101/2024.07.18.604039 — microbiology — Posted on 2024-07-18

2256 Using the basic reproduction ratio to quantify transmission and identify data gaps for epizootic haemorrhagic disease, an emerging vector-borne disease in Europe

Gubbins, S.

10.1101/2024.07.18.604050 — microbiology — Posted on 2024-07-18

2257 Global survey of secondary metabolism in Aspergillus niger via activation of specific transcription factors

Semper, C.; Pham, T. T. M.; Ram, S.; Palys, S.; Evdokias, G.; Ouedraogo, J.-P.; Moisan, M.-C.; Geoffrion, N.; Reid, I.; Di Falco, M.; Bailey, Z.; Tsang, A.; Benoit-Gelber, I.; Savchenko, A.

10.1101/2024.07.18.604165 — microbiology — Posted on 2024-07-18

2258 Identifying essential genes in Schaalia odontolytica using a highly-saturated transposon library

Bedree, J. K.; Bourgeois, J.; Balani, P.; Cen, L.; Hendrickson, E.; Kerns, K.; Camilli, A.; McLean, J. S.; He, X.

10.1101/2024.07.17.604004 — microbiology — Posted on 2024-07-18

2259 Primary bovine white blood cells support dissemination of Lumpy Skin Disease Virus while suppressing viral replication

Kumar, M.; Frid, O.; Sol, A.; Rouvinski, A.; Karniely, S.

10.1101/2024.07.18.604162 — microbiology — Posted on 2024-07-18

2260 When is microbial strain sharing evidence for transmission?

Debray, R. R.; Dickson, C. C.; Webb, S. E.; Archie, E. A.; Tung, J.

10.1101/2024.07.18.604082 — microbiology — Posted on 2024-07-18

2261 The role of stomatin-like protein (STOML) in Plasmodium falciparum

Verhoef, J. M. J.; Bekkering, E. T.; Boshoven, C.; Hannon, M.; Proellochs, N.; Spruijt, C. G.; Kooij, T. W. A.

10.1101/2024.07.18.604071 — microbiology — Posted on 2024-07-18

2262 Biochar Modulates Wheat Root Metabolome and Rhizosphere Microbiome in a Feedstock-dependent Manner

Yang, H.; Kerner, P.; Liang, X.; Struhs, E.; Mirkouei, A.; You, Y.

10.1101/2024.07.17.604021 — microbiology — Posted on 2024-07-18

2263 Probing the eukaryotic microbes of ruminants with a deep-learning classifier and comprehensive protein databases

Yan, M.; Andersen, T. O.; Pope, P. B.; Yu, Z.

10.1101/2024.07.17.603995 — microbiology — Posted on 2024-07-18

2264 Rapid protein evolution by few-shot learning with a protein language model

Jiang, K.; Yan, Z.; Bernardo, M. D.; Sgrizzi, S. R.; Villiger, L.; Kayabolen, A.; Kim, B.; Carscadden, J. K.; Hiraizumi, M.; Nishimasu, H.; Gootenberg, J. S.; Abudayyeh, O. O.

10.1101/2024.07.17.604015 — bioengineering — Posted on 2024-07-18

2265 Sensing endogenous RNA in living human cells using a CRISPR-activated protease

Blumenstock, K.; Hoch, A.; Hinterlang, L. D.; Caroline, F.; Schneberger, N.; Hagelueken, G.; Schmid-Burgk, J. L.

10.1101/2024.07.17.603943 — bioengineering — Posted on 2024-07-18

2266 Inference of gene regulatory networks for overcoming low performance in real-world data

Hiki, Y.; Yamada, T. G.; Tokuoka, Y.; Funahashi, A.

10.1101/2024.07.16.603684 — systems biology — Posted on 2024-07-18

2267 Inter-individual variability in motor learning due to differences in effective learning rates between generalist and specialist memory stores

Osu, R.; Sugimoto, N.; Yoshioka, T.; Schweighofer, N.; Kawato, M.

10.1101/2024.07.15.603502 — neuroscience — Posted on 2024-07-18

2268 Transcriptome-wide alternative mRNA splicing analysis reveals post-transcriptional regulation of neuronal differentiation.

Zhou, Y.; Rashad, S.; Niizuma, K.

10.1101/2024.07.16.603656 — neuroscience — Posted on 2024-07-18

2269 Systematic Targeting of Protein Complexes with Molecular COUPLrs

Yang, D.; Harry, S.; Chong, H.; Zhang, E.; Nordenfelt, N.; Chen, N.; Lee, C.; Kaluziak, S.; Codd, E.; Trivedi, S.; Gohar, M.; McKnight, G.; Mitchell, D.; Ge, M.; Gao, C.; Holmes, Z.; Yang, W.; Smith, A.; Carlin, A.; Lazarov, M.; Khandelwal, N.; Takahashi, M.; Zhang, S.; Leong, H.; Martinez Luna, H.; Chearavanont, Z.; Emonds, K.; Popoola, G.; Barakat, I.; Onozato, M.; Mahamdeh, M. S. S.; Fujino, T.; Seo, H.-S.; Dhe-Paganon, S.; Sun, Z.-Y.; Heffron, G.; Hata, A.; Soberman, R.; Liau, B.; Iafrate, A. J.; bar-peled, l.

10.1101/2024.07.16.603666 — systems biology — Posted on 2024-07-18

2270 Machine learning nominal max oxygen consumption from wearable reflective pulse oximetry with density functional theory

Al Dajani, S. A. F.; Laquai, F.

10.1101/2024.07.15.603651 — biophysics — Posted on 2024-07-18

2271 Free energy profiles of temozolomide crossing brain plasma membranes

Ge, Y.; LU, H.; Marti, J.

10.1101/2024.07.16.603685 — biophysics — Posted on 2024-07-18

2272 SmartImpute: A Targeted Imputation Framework for Single-cell Transcriptome Data

Yao, S.; Yu, X.; Wang, X.

10.1101/2024.07.15.603649 — bioinformatics — Posted on 2024-07-18

2273 Weighted Ensemble Approach for Knowledge Graph completion improves performance

Sinha, M.; Tu, R.; Gonzalez, C.; Su, A. I.

10.1101/2024.07.16.603664 — bioinformatics — Posted on 2024-07-18

2274 GPS-Net: discovering prognostic pathway modules based on network regularized kernel learning

Yao, S.; Li, K.; Li, T.; Yu, X.; Kuan, P. F.; Wang, X.

10.1101/2024.07.15.603645 — bioinformatics — Posted on 2024-07-18

2275 Natural variation in fruiting body morphology in the amoeba Dictyostelium discoideum

Broersma, C. M. E.; McFadyen, S.; Ostrowski, E. A.

10.1101/2024.07.16.603515 — evolutionary biology — Posted on 2024-07-18

2276 Trained Immunity Causes Myeloid Cell Hypercoagulability

Rehill, A. M.; McCluskey, S.; Ledwith, A. E.; Ryan, T. A.; Leon, G.; Charles-Messance, H.; Gilbert, E. H.; Day, E. A.; McMahon, C.; O'Donnell, J. S.; Curtis, A. M.; O'Neill, L. A.; Sheedy, F. J.; Preston, R. J.

10.1101/2024.07.16.603679 — immunology — Posted on 2024-07-18

2277 Multimodal MEG and microstructure-MRI investigations of the human hippocampal scene network

Read, M.-L.; Hodgetts, C. J.; Lawrence, A. D.; Evans, C. J.; Singh, K. D.; Umla-Runge, K.; Graham, K. S.

10.1101/2024.07.16.603546 — neuroscience — Posted on 2024-07-18

2278 Sst- and Vip-Cre mouse lines without age-related hearing loss

Foss, C. T.; Olsen, T.; Bigelow, J.; Hasenstaub, A. R.

10.1101/2024.07.15.603003 — neuroscience — Posted on 2024-07-18

2279 Differences in drug intake levels (high versus low takers) do not necessarily imply distinct drug user types: insights from a new cluster-based model

Castaneda, D. M.; Job, M.

10.1101/2024.07.15.603634 — neuroscience — Posted on 2024-07-18

2280 Cognitive hyperplasticity drives insomnia

Huang, S.; Piao, C.; Zhao, Z.; Beuschel, C. B.; Turrel, O.; Toppe, D.; Sigrist, S. J.

10.1101/2024.07.16.603670 — neuroscience — Posted on 2024-07-18

2281 A universal cannabinoid CB1 and CB2 receptor TR-FRET kinetic ligand binding assay.

Borrega-Roman, L.; Hoare, B. L.; Kosar, M.; Sarott, R. C.; Patej, K. J.; Bouma, J.; Scott-Dennis, M.; Koers, E. J.; Gazzi, T.; Mach, L.; Barrondo, S.; Salles, J.; Guba, W.; Kusznir, E.; Nazare, M.; Rufer, A. C.; Grether, U.; Heitman, L. H.; Carreira, E. M.; Sykes, D. A.; Veprintsev, D. B.

10.1101/2024.07.16.603654 — pharmacology and toxicology — Posted on 2024-07-18

2282 An epidemiological description of rabies outbreaks in Zambia from 2013 to 2023.

kachinda, w.; Banda, H.; Hamukale, A.; Makungu, C.; Ngoma, M.; Chazya, R.; Mataa, L.; Mulenga, C.; Banda, J. B.; Muleya, W.; Sialubanje, C.; Banda, D.; Sinyange, N.

10.1101/2024.07.16.603659 — pathology — Posted on 2024-07-18

2283 Integrated multiomic profiling reveals SWI/SNF subunit-specific pathway alterations and targetable vulnerabilities

Bretones-Santamarina, J.; Astier, C.; Garrido, M.; Colmet-Daage, L.; Roumeliotis, T. I.; Anthony, E.; Pardo, M.; Chasseriaud, M.; Gestraud, P.; Ngo, C.; Morel, D.; Chabanon, R.; Chaudhary, J. S.; Del Nery, E.; Postel-Vinay, S.; Ballesta, A.

10.1101/2024.07.16.603530 — cancer biology — Posted on 2024-07-18

2284 Flexynesis: A deep learning framework for bulk multi-omics data integration for precision oncology and beyond

Uyar, B.; Savchyn, T.; Wurmus, R.; Sarigun, A.; Shaik, M. M.; Franke, V.; Akalin, A.

10.1101/2024.07.16.603606 — bioinformatics — Posted on 2024-07-18

2285 Normalization strategies for lipidome data in cell line panels

Leegwater, H.; Zhang, Z.; Zhang, X.; Hankemeier, T.; Harms, A. C.; Zweemer, A. J. M.; Le Devedec, S. E.; Kindt, A.

10.1101/2024.07.16.600977 — bioinformatics — Posted on 2024-07-18

2286 Wireless, Multimodal Monitoring of Organ Health Using 3D-Printed, Barbed, Bioresorbable Stretchable Microneedle Sensor Arrays

Li, X.; Liu, S.; Mo, J.; Yang, C.; Morales, M.; Ouyang, W.

10.1101/2024.07.16.603523 — bioengineering — Posted on 2024-07-18

2287 Queens from a unique hyper-dense Lasius niger population tolerate pleometrosis better than queens from a 'normal' population

Stukalyuk, S.; Czaczkes, T.

10.1101/2024.07.16.603683 — animal behavior and cognition — Posted on 2024-07-18

2288 Agricultural landscapes with high compositional heterogeneity support both forest and farmland birds in Taiwan

Lin, D.-L.; Amano, T.; Fuller, R.; Ding, T.-S.; Maron, M.

10.1101/2024.07.16.603643 — ecology — Posted on 2024-07-18

2289 A third kind of episodic memory: Context familiarity is a distinct process from item familiarity and recollection

Addante, R. J.; Clise, E.; Waechter, R.; Bengson, J.; Drane, D. L.; Perez-Caban, J.

10.1101/2024.07.15.603640 — neuroscience — Posted on 2024-07-18

2290 Temporal profiling of the phosphate starvation response in Arabidopsis root hair cells reveals that induction of polycomb target genes does not depend on removal of H3K27me3 or H2A.Z

Holder, D. H.; Deal, R. B.

10.1101/2024.07.14.603443 — plant biology — Posted on 2024-07-18

2291 SWR1 is recruited to activated ABA response genes to maintain gene body H2A.Z in Arabidopsis thaliana

Krall, E. G.; Deal, R. B.

10.1101/2024.07.14.603444 — plant biology — Posted on 2024-07-18

2292 Gelatinous matrix, an original strategy to cope with oligotrophy in Nassellaria (Radiolaria)

Llopis Monferrer, N.; Romac, S.; Laget, M.; Nakamura, Y.; Biard, T.; Sandin, M. M.

10.1101/2024.01.22.576765 — evolutionary biology — Posted on 2024-07-18

2293 sdmTMB: an R package for fast, flexible, and user-friendly generalized linear mixed effects models with spatial and spatiotemporal random fields

Anderson, S. C.; Ward, E. J.; English, P. A.; Barnett, L. A. K.; Thorson, J. T.

10.1101/2022.03.24.485545 — ecology — Posted on 2024-07-18

2294 MuSK-BMP signaling in adult muscle stem cells maintains quiescence and regulates myofiber size

Madigan, L. A.; Jaime, D.; Chen, I.; Fallon, J. R.

10.1101/2023.05.17.541238 — cell biology — Posted on 2024-07-18

2295 Bacterial Protein Signatures Identified in Porphyromonas gingivalis Containing-Autophagic Vacuoles Reveal Co-Evolution Between Oral Red/Orange Complex Bacteria and Gut Bacteria

Paul, A.; Wellslager, B.; Williamson, M.; Yilmaz, O.

10.1101/2024.07.11.602567 — microbiology — Posted on 2024-07-18

2296 Mutations in the riboflavin biosynthesis pathway confer resistance to furazolidone and abolish the synergistic interaction between furazolidone and vancomycin in Escherichia coli.

Wykes, H.; Le, V. V. H.; Rakonjac, J.

10.1101/2024.07.17.603971 — microbiology — Posted on 2024-07-18

2297 State dependent motor cortex stimulation reveals distinct mechanisms for corticospinal excitability and cortical responses

Perera, N. D.; Wischnewski, M.; Alekseichuk, I.; Shirinpour, S.; Opitz, A.

10.1101/2024.07.15.603619 — neuroscience — Posted on 2024-07-18

2298 Mathematical model of transcription loss due to accumulated DNA damage

Raseta, M.; Grint, J. v. d.; Dealy, S.; Chang, J.; Hoeijmakers, J.; Pothof, J.

10.1101/2024.07.15.603615 — systems biology — Posted on 2024-07-18

2299 Insights into the role of root exudates in bacteriophage infection dynamics

Novak, V.; van Winden, M. C. M.; Harwood, T. V.; Neurath, R.; Kosina, S. M.; Louie, K. B.; Sullivan, M. B.; Roux, S.; Zengler, K.; Mutalik, V. K.; Northen, T. R.

10.1101/2024.07.15.603626 — plant biology — Posted on 2024-07-18

2300 An Adipo-Pulmonary Axis Mediated by FABP4 Hormone Defines a Therapeutic Target Against Obesity-Induced Airway Disease

Burak, M. F.; Tuncman, G.; Ayci, A. N.; Chetal, K.; Lee Seropian, G. Y.; Inouye, K. E.; Lai, Z. W.; Dagtekin, N.; Sadreyev, R. E.; Israel, E.; Hotamisligil, G. S.

10.1101/2024.07.15.603433 — physiology — Posted on 2024-07-18

2301 Classification of dinosaur footprints using machine learning

Jones, M.; Lallensack, J. N.; Jarman, I.; Falkingham, P.; Siekmann, I.

10.1101/2024.07.15.603597 — paleontology — Posted on 2024-07-18

2302 YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells

Kovar, H.; Noorizadeh, R.; Sax, B.; Javaheri, T.; Radic Sarikas, B.; Fock, V.; Kauer, M.; Bykov, A.; Suresh, V.; Schlederer, M.; Kenner, L.; Weber, G.; Mikulits, W.; Halbritter, F.; Moriggl, R.

10.1101/2024.07.15.603565 — cancer biology — Posted on 2024-07-18

2303 Selective binding of MLX to triacylglycerol-rich lipid droplets: Mechanisms of cytosolic localization and proteome regulation

Braun, R. J.; Swanson, J. M.

10.1101/2024.07.15.603605 — biophysics — Posted on 2024-07-18

2304 Employing Steered MD Simulations for Effective Virtual Screening: Active Pharmacophore Search by Dynamic Corrections to target MKK3-MYC Interactions

Ulug, M. E.; Ikram, S.; Sayyah, E.; Durdagi, S.

10.1101/2024.07.15.603633 — bioinformatics — Posted on 2024-07-18

2305 Simultaneous acclimation to nitrogen and iron scarcity in open ocean cyanobacteria revealed by sparse tensor decomposition of metatranscriptomes

Blaskowski, S.; Roald, M.; Berube, P. M.; Braakman, R.; Armbrust, E. V.

10.1101/2024.07.15.603627 — bioinformatics — Posted on 2024-07-18

2306 Peptide Coated Polycaprolactone-Benzalkonium Chloride Nanocapsules for Targeted Drug Delivery to the Pancreatic β-Cell

Collins, J.; Barra, J. M.; Holcomb, K.; Ocampo, A.; Fremin, A.; Akolade, J.; Kratz, A.; Hays, J. K.; Shilleh, A.; Hodson, D. J.; Broichhagen, J. J.; Russ, H. A.; Farnsworth, N. L.

10.1101/2024.07.15.603612 — bioengineering — Posted on 2024-07-18

2307 Visual field asymmetries in responses to ON and OFF pathway biasing stimuli

Scott, M. T. W.; Yakovleva, A.; Norcia, A. M.

10.1101/2024.07.15.603635 — neuroscience — Posted on 2024-07-18

2308 Automatic dendritic spine segmentation in widefield fluorescence images reveal synaptic nanostructures distribution with super-resolution imaging

Zhang, J.; Vaidya, R. M.; Chung, H. J.; Selvin, P. R.

10.1101/2024.07.15.603616 — neuroscience — Posted on 2024-07-18

2309 Lipid packing and cholesterol content regulate membrane wetting by biomolecular condensates.

Mangiarotti, A.; Schmidt, K. V.; Lipowsky, R.; Dimova, R.

10.1101/2024.07.15.603610 — biophysics — Posted on 2024-07-18

2310 Automated Skin Lesion Detection and Prevalence Estimation in Tamanend's Bottlenose Dolphins

Murphy, C. J.; Collier, M. A.; Jacoby, A.-M.; Patterson, E. M.; Wallen, M. M.; Mann, J.; Bansal, S.

10.1101/2024.07.15.603578 — ecology — Posted on 2024-07-18

2311 Variation in a microbial mutualist has cascading consequences for host-parasite interactions

Buxton-Martin, A.; Gluck-Thaler, E.; Yi, E.; Stinchcombe, J. R.; Wood, C. W.

10.1101/2024.07.15.603596 — ecology — Posted on 2024-07-18

2312 Branched actin networks in innate immune cells mediate host microbiota homeostasis.

Vasconcellos, L. R.; Huang, S. C. M.; Suarez-Bonnet, A.; Priestnall, S.; Varsani-Brown, S.; Winder, M. L.; Shah, K.; Kogata, N.; Stockinger, B.; Way, M.

10.1101/2024.07.18.604111 — immunology — Posted on 2024-07-18

2313 Resistance to age-related hearing loss in the echolocating big brown bat (Eptesicus fuscus)

Capshaw, G.; Diebold, C. A.; Adams, D. M.; Rayner, J.; Wilkinson, G. S.; Moss, C. F.; Lauer, A. M.

10.1101/2024.07.15.603592 — neuroscience — Posted on 2024-07-18

2314 SV2A is expressed in synapse subpopulations in mouse and human brain: implications for PET radiotracer studies

Wong, T.; Qiu, Z.; Notman, B.; Tavares, A.; Smith, C.; Grant, S. G. N.

10.1101/2024.07.15.603608 — neuroscience — Posted on 2024-07-18

2315 The Neurobiology of Cognitive Fatigue and Its Influence on Effort-Based Choice

Steward, G. E.; Chib, V. S.

10.1101/2024.07.15.603598 — neuroscience — Posted on 2024-07-18

2316 Simulations of the infant gut microbiota suggest that complex ecological interactions regulate effects of human milk oligosaccharides on microbial mucin consumption

Versluis, D. M.; Wijtkamp, C.; Looijesteijn, E.; Geurts, J. M. W.; Merks, R. M. H.

10.1101/2024.07.15.603541 — systems biology — Posted on 2024-07-18

2317 Modeling the effect of daytime duration on the biosynthesis of terpenoid precursors

Basallo, O.; Lucido, A.; Sorribas, A.; Marin-Sanguino, A.; Martinez, E.; Vilaprinyo, E.; Eleiwa, A.; Alves, R.

10.1101/2024.07.15.603555 — systems biology — Posted on 2024-07-18

2318 Additive and partially dominant effects contribute to crop heterosis

Dan, Z.; Chen, Y.; Zhou, W.; Xu, Y.; Huang, J.; Chen, Y.; Meng, J.; Yao, G.; Huang, W.

10.1101/2024.07.16.603817 — plant biology — Posted on 2024-07-18

2319 Effect of Voltage-Gated K+ Channel Inhibition by 4-aminopyridine in Spinal Cord Injury Recovery in Zebrafish

Hoffman, P.; Mruk, K.

10.1101/2024.07.15.603582 — pharmacology and toxicology — Posted on 2024-07-18

2320 UTRGAN: Learning to Generate 5' UTR Sequences for Optimized Translation Efficiency and Gene Expression

Barazandeh, S.; Ozden, F.; Hincer, A.; Seker, U. O. S.; Cicek, A. E.

10.1101/2023.01.30.526198 — bioinformatics — Posted on 2024-07-18

2321 Exploring Harmala Alkaloids as Novel Antimalarial Agents against Plasmodium falciparum through Bioinformatics Approaches

Dipto, K. Z.; Shariar, R.; Saha, C. K.; Huzaifa, A.; Robin, T. B.; Patil, R. B.; Alam, M. T.; Rafi, M. I. H.; Faruk, A. Z.; Moin, A. T.; Zinnah, K. M. A.; Hasanuzzaman, M.; Islam, T.

10.1101/2024.07.17.603828 — bioinformatics — Posted on 2024-07-18

2322 diaPASEF Enables High-throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development

Tsukidate, T.; Stiving, A. Q.; Rivera, S.; Sahoo, A.; Madhabushi, S.; Li, X.

10.1101/2024.02.21.581388 — bioengineering — Posted on 2024-07-18

2323 Butyrate as a growth factor of Clostridium acetobutylicum

Seo, H.; Capece, S.; Hill, J. D.; Otten, J.; PAPOUTSAKIS, E. T.

10.1101/2024.07.15.603595 — bioengineering — Posted on 2024-07-18

2324 Plant functional types and tissue stoichiometry explain nutrient transfer in common arbuscular mycorrhizal networks of temperate grasslands

Dawson, H. R.; Shek, K. L.; Maxwell, T. M.; Reed, P. B.; Bomfim, B.; Bridgham, S.; Bohannan, B.; Silva, L. C. R.

10.1101/2022.10.05.511035 — ecology — Posted on 2024-07-18

2325 Protrudin acts at ER-endosome contacts to promote KIF5-mediated endosomal fission and endosome-to-Golgi transport

Kleniuk, J.; Nadadhur, A. G.; Wolfenden, E.; Rodger, C.; Zlamalova, E.; Reid, E.

10.1101/2024.07.15.602703 — cell biology — Posted on 2024-07-18

2326 'Off-pore' nucleoporins relocalize heterochromatic breaks through phase separation

Merigliano, C.; Ryu, T.; See, C. D.; Caridi, C. P.; Li, X.; Butova, N.; Reynolds, T.; Deng, C.; Chenoweth, D. M.; Capelson, M.; Chiolo, I.

10.1101/2023.12.07.570729 — cell biology — Posted on 2024-07-18

2327 Acoustically evoked K-complexes together with sleep spindles boost verbal declarative memory consolidation in healthy adults

Leach, S.; Krugliakova, E.; Sousouri, G.; Snipes, S.; Scorucak, J.; Schuehle, S.; Mueller, M.; Ferster, M. L.; Da Poian, G.; Karlen, W.; Huber, R.

10.1101/2023.06.29.546822 — neuroscience — Posted on 2024-07-18

2328 Stimulus invariant aspects of the retinal code drive discriminability of natural scenes

Hoshal, B.; Holmes, C. M.; Bojanek, K.; Salisbury, J. M.; Berry, M. J.; Marre, O.; Palmer, S.

10.1101/2023.08.08.552526 — neuroscience — Posted on 2024-07-18

2329 Prefrontal metabolite alterations in individuals with posttraumatic stress disorder: a 7T magnetic resonance spectroscopy study

Reid, M. A.; Whiteman, S. E.; Camden, A. A.; Jeffirs, S. M.; Weathers, F. W.

10.1101/2024.07.16.603137 — neuroscience — Posted on 2024-07-18

2330 Appearance of green tea compounds in plasma following green tea consumption is modulated by the gut microbiome in mice

Sterrett, J. D.; Quinn, K. D.; Doenges, K. A.; Nusbacher, N.; Levens, C. L.; Armstrong, M. L.; Reisdorph, R. M.; Smith, H.; Saba, L. M.; Kuhn, K. A.; Lozupone, C.; Reisdorph, N.

10.1101/2024.07.11.603097 — systems biology — Posted on 2024-07-18

2331 Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

Estevam, G. O.; Linossi, E. M.; Rao, J.; Macdonald, C. B.; Ravikumar, A.; Chrispens, K. M.; Capra, J. A.; Coyote-Maestas, W.; Pimentel, H.; Collisson, E. A.; Jura, N.; Fraser, J. S.

10.1101/2024.07.16.603579 — cancer biology — Posted on 2024-07-18

2332 RNAGEN: A generative adversarial network-based model to generate synthetic RNA sequences to target proteins

Ozden, F.; Barazandeh, S.; Akboga, D.; Shokoueian Tabrizi, S.; Seker, U. O. S.; Cicek, A. E.

10.1101/2023.07.11.548246 — bioinformatics — Posted on 2024-07-18

2333 Computational structural prediction and chemical inhibition of the human mitochondrial pyruvate carrier protein heterodimer complex

Hadfield, C. M.; Walker, J. K.; Dastvan, R.; Arnatt, C.; McCommis, K. S.

10.1101/2024.05.16.594520 — biochemistry — Posted on 2024-07-18

2334 WITHDRAWN: Unveiling the Family of Optimal Accelerations in Minimax Optimization and Fixed-Point Algorithms

Li, C. J.

10.1101/2024.06.29.601352 — genetics — Posted on 2024-07-18

2335 Exploring TAS2R46 Biomechanics through Molecular Dynamics and Network Analysis

Cannariato, M.; Fanunza, R.; Zizzi, E. A.; Miceli, M.; Di Benedetto, G.; Deriu, M. A.; Pallante, L.

10.1101/2023.11.21.568072 — bioengineering — Posted on 2024-07-18

2336 A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification

Wiegering, A.; Anselme, I.; Brunetti, L.; Metayer-Derout, L.; Calderon, D.; Thomas, S.; Nedelec, S.; Eschstruth, A.; Serpieri, V.; catala, m.; Antoniewski, C.; Schneider-Maunoury, S.; STEDMAN, A.

10.1101/2024.02.28.582477 — developmental biology — Posted on 2024-07-18

2337 Pseudocobalamin production and use in marine Synechococcus cultures and communities

Bannon, C. C.; Soto, M. A.; Rowland, E.; Chen, N.; Gleason, A.; Devred, E.; LaRoche, J.; Bertrand, E. M.

10.1101/2024.04.01.587587 — microbiology — Posted on 2024-07-18

2338 Rhythmic sampling of multiple decision alternatives in the human brain

Siems, M.; Cao, Y.; Tohidi-Moghaddam, M.; Donner, T. H.; Tsetsos, K.

10.1101/2023.12.08.570734 — neuroscience — Posted on 2024-07-18

2339 Subjective confidence modulates individual BOLD patterns of predictive processing

Hechler, A.; de Lange, F.; Riedl, V.

10.1101/2024.02.23.581697 — neuroscience — Posted on 2024-07-18

2340 Age associated alterations in the cortical representation of cardiac signals: A heartfelt tale

Saluja, K.; Roy, D.; Banerjee, A.

10.1101/2024.05.31.596844 — neuroscience — Posted on 2024-07-18

2341 A high-light tolerant alga from the desert is protected from oxidative stress by NPQ-independent responses

Levin, G.; Yasmin, M.; Liran, O.; Hanna, R.; Kleifeld, O.; Horev, G.; Wollman, F.-A.; Schuster, G.; Nawrocki, W. J.

10.1101/2024.06.10.598256 — plant biology — Posted on 2024-07-18

2342 PD-1 Targeted Antibody Discovery Using AI Protein Diffusion

Ford, C. T.

10.1101/2024.01.18.576323 — cancer biology — Posted on 2024-07-18

2343 Astrocytes are active: An information theoretic approach reveals differences in Ca2+ signaling patterns among distinct astrocyte subtypes

Mennona, N. J.; Barile, B.; Kang, H.; Benfenati, V.; Nicchia, G. P.; O'Neill, K. M.; Losert, W.

10.1101/2023.11.01.565176 — biophysics — Posted on 2024-07-18

2344 miRglmm: a generalized linear mixed model of isomiR-level counts improves estimation of miRNA-level differential expression and uncovers variable differential expression between isomiRs

Baran, A. M.; Patil, A. H.; Aparicio, E. L.; Halushka, M. K.; McCall, M. N.

10.1101/2024.05.03.592274 — bioinformatics — Posted on 2024-07-18

2345 Identifiability of speciation times under the multispecies coalescent

Kubatko, L.; Leonard, A.; Chifman, J.

10.1101/2020.11.24.396424 — evolutionary biology — Posted on 2024-07-18

2346 Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird

Bloch, I.; Troupin, D.; Toledo, S.; Nathan, R.; Sapir, N.

10.1101/2024.02.18.580922 — ecology — Posted on 2024-07-18

2347 A cryo-ET study of ciliary rootlet organization

van Hoorn, C.; Carter, A. P.

10.1101/2023.09.03.556114 — molecular biology — Posted on 2024-07-18

2348 Primary auditory thalamus relays directly to cortical layer 1 interneurons

Vattino, L. G.; MacGregror, C. P.; Liu, C. J.; Sweeney, C. G.; Takesian, A. E.

10.1101/2024.07.16.603741 — neuroscience — Posted on 2024-07-18

2349 Identifying Artifacts from Large Library Docking

Wu, Y.; Liu, F.; Glenn, I.; Fonseca-Valencia, K.; Paris, L.; Xiong, Y.; Jerome, S. V.; Brooks, C. L.; Shoichet, B. K.

10.1101/2024.07.17.603966 — biophysics — Posted on 2024-07-18

2350 Metabolic phenotyping of healthy and diseased human RPE cells

Rizwan, S.; Toothman, B.; Li, B.; Engel, A. J.; Lim, R. R.; Niernberger, S.; Lu, J.; Ratcliff, C.; Xiang, Y.; Eminhizer, M.; Chao, J. R.; Du, J.

10.1101/2024.02.28.582405 — biochemistry — Posted on 2024-07-18

2351 Temporal and spatial variability in availability bias has consequences for marine bird abundance estimates during the non-breeding season

Dunn, R. E.; Duckworth, J.; O'Brien, S.; Furness, R. W.; Buckingham, L.; Daunt, F.; Bogdanova, M. I.; Green, J. A.

10.1101/2024.03.13.584773 — ecology — Posted on 2024-07-18

2352 Control of lumen geometry and topology by the interplay between pressure and cell proliferation rate in pancreatic organoids

Lee, B. H.; Fuji, K.; Petzold, H.; Seymour, P. A.; Yennek, S.; Schewin, C.; Lewis, A.; Riveline, D.; Hiraiwa, T.; Sano, M.; Grapin-Botton, A.

10.1101/2024.05.29.596462 — developmental biology — Posted on 2024-07-18

2353 Overexpression of enhanced yellow fluorescent protein fused with Channelrhodopsin-2 causes contractile dysfunction in skeletal muscle

Lamia, S. N. E.; Davis, C. S.; Macpherson, P. C. D.; Willingham, B.; Zhang, Y.; Liu, C.; Iannucci, L.; Ganji, E.; Harden, D.; Bhattacharya, I.; Abraham, A. C.; Brooks, S. V.; Glancy, B.; Killian, M. L.

10.1101/2024.06.06.597782 — physiology — Posted on 2024-07-18

2354 A heterogeneous pool of tumor precursor cells with self-replenishing and tumor-originating properties in Chronic Lymphocytic Leukemia

Budeus, B.; Dampmann, M.; Kibler, A.; Fassbender, B.; Brauser, M.; Bronischewski, K.; Homp, E.; Taudien, S.; Johansson, P.; Bloehdorn, J.; Stilgenbauer, S.; von Tresckow, J.; Duerig, J.; Reinhardt, H. C.; Kueppers, R.; Dietrich, S.; Seifert, M.

10.1101/2022.05.04.490383 — cancer biology — Posted on 2024-07-18

2355 Detection of changes in membrane potential by magnetic resonance imaging

Min, K.; Chung, S.; Lee, S.-K.; Lee, J.; Toi, P. T.; Kim, D.; Lee, J. S.; Park, J.-Y.

10.1101/2024.04.02.587661 — biophysics — Posted on 2024-07-18

2356 Mechanism of host cell invasion by Leishmania through KMP-11 mediated cholesterol-transport and membrane phase transition

Chattopadhyay, K.; Sannigrahi, A.; Ghosh, S.; Jana, P.; Jawed, J. J.; Pradhan, S.; Majumdar, S.; Roy, S.; Karmakar, S.; Mukherjee, B.

10.1101/2024.07.15.603533 — biophysics — Posted on 2024-07-18

2357 CellPie: a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization

Georgaka, S.; Morgans, W. G.; Zhao, Q.; Sanchez Martinez, D.; Ali, A.; Ghafoor, M.; Baker, S. M.; Bristow, R.; Iqbal, M.; Rattray, M.

10.1101/2023.09.29.560213 — bioinformatics — Posted on 2024-07-18

2358 SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency

Ochiai, Y.; Clifton, B. E.; Coz, M. L.; Terenzio, M.; Laurino, P.

10.1101/2023.08.23.554385 — biochemistry — Posted on 2024-07-18

2359 On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation

Krokengen, O. C.; Raasakka, A.; Klenow, M. B.; Pal, A.; Hetland, O.; Mularski, A.; Ruskamo, S.; Pedersen, J. S.; Simonsen, A. C.; Kursula, P.

10.1101/2024.07.15.603506 — biochemistry — Posted on 2024-07-18

2360 Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cells

Wu, W.; Lam, A. R.; Suarez, K.; Smith, G. N.; Duquette, S. M.; Yu, J.; Mankus, D.; Bisher, M.; Lytton-Jean, A.; Manalis, S. R.; Miettinen, T. P.

10.1101/2024.07.02.601447 — cell biology — Posted on 2024-07-18

2361 Urban non-point source pollutants cause microbial community homogenization via increasing deterministic processes

Li, H.; Fan, X.; He, Z.; Fu, J.; Wang, Y.; Yang, S.; Wu, J.; Wu, L.; Zhou, J.

10.1101/2023.08.21.553702 — microbiology — Posted on 2024-07-18

2362 Synthesis of geometrically realistic and watertight neuronal ultrastructure manifolds for in silico modeling

Abdellah, M.; Foni, A.; Garcia Cantero, J. J.; Roman Guerrero, N.; Boci, E.; Fleury, A.; Coggan, J. S.; Keller, D.; Planas, J.; Courcol, J.-D.; Khazen, G.

10.1101/2024.03.11.584388 — neuroscience — Posted on 2024-07-18

2363 A spatial model of autophosphorylation of Ca2+/calmodulin-dependent protein kinase II in a glutamatergic spine reveals dynamics of kinase activation in the first several seconds after a complex synaptic stimulus.

Bartol, T. M.; Ordyan, M.; Sejnowski, T. J.; Rangamani, P.; Kennedy, M. B.

10.1101/2024.02.02.578696 — neuroscience — Posted on 2024-07-18

2364 Expanded Genome and Proteome Reallocation in a Novel, Robust Bacillus coagulans Capable of Utilizing Pentose and Hexose Sugars

Dooley, D.; Ryu, S.; Giannone, R. J.; Edwards, J.; Dien, B. S.; Slininger, P.; Trinh, C. T.

10.1101/2024.07.15.603586 — systems biology — Posted on 2024-07-18

2365 OsNF-YB7 inactivates OsGLK1 to inhibit chlorophyll biosynthesis in rice embryo

Yang, Z.; Bai, T.; E, Z.; Niu, B.; Chen, C.

10.1101/2024.02.05.578907 — plant biology — Posted on 2024-07-18

2366 Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma

Karnan, S.; Ota, A.; Hasan, M. N.; Murakami, H.; Rahman, M. L.; Wahiduzzaman, M.; Shihan, M. T. A.; Jahan, N.; Vu, L. Q.; Hanamura, I.; Inoko, A.; Riku, M.; Ito, H.; Kaneko, Y.; Lin, Y.; Hyodo, T.; Konishi, H.; Tsuzuki, S.; Hosokawa, Y.

10.1101/2024.07.14.603191 — cancer biology — Posted on 2024-07-18

2367 RFMix-reader: Accelerated reading and processing for local ancestry studies

Benjamin, K. J. M.

10.1101/2024.07.13.603370 — bioinformatics — Posted on 2024-07-18

2368 Identification of spatial homogeneous regions in tissues with concordex

Jackson, K. C.; Booeshaghi, A. S.; Galvez-Merchan, A.; Moses, L.; Chari, T.; Kim, A.; Pachter, L.

10.1101/2023.06.28.546949 — bioinformatics — Posted on 2024-07-18

2369 Ribosomal RNA methylation by GidB modulates discrimination of mischarged tRNA

Bi, Z.; Chen, Y.-X.; Young, I. D.; Su, H.; Chen, Y.; Hong, J.; Fraser, J. S.; Javid, B.

10.1101/2021.03.02.433644 — molecular biology — Posted on 2024-07-18

2370 tRNA modifications inform tissue specific mRNA translation and codon optimization.

Ando, D.; Rashad, S.; Begley, T.; Endo, H.; Aoki, M.; Dedon, P.; Niizuma, K.

10.1101/2023.10.24.563884 — molecular biology — Posted on 2024-07-18

2371 Transformation of valence signaling in a striatopallidal circuit

Lee, D.; Lau, N.; Liu, L.; Root, C. M.

10.1101/2023.08.01.551547 — neuroscience — Posted on 2024-07-18

2372 Fixational Eye Movements Enhance the Precision of Visual Information Transmitted by the Primate Retina

Wu, E. G.; Brackbill, N.; Rhoades, C. E.; Kling, A.; Gogliettino, A. R.; Shah, N. P.; Sher, A.; Litke, A. M.; Simoncelli, E. P.; Chichilnisky, E. J.

10.1101/2023.08.12.552902 — neuroscience — Posted on 2024-07-18

2373 Geometrical determinant of nonlinear synaptic integration in human cortical pyramidal neurons

Yoon, J.

10.1101/2024.07.14.601255 — neuroscience — Posted on 2024-07-18

2374 Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis

Verzino, S. J.; Priyev, S. A.; Sanchez Estrada, V. A.; Crowley, G. X.; Rutkowski, A.; Lam, A. C.; Nazginov, E. S.; Kotemelo, P.; Bacelo, A.; Sukhram, D. T.; Vazquez, F. X.; Fernandez Juarez, J.

10.1101/2024.06.13.598939 — synthetic biology — Posted on 2024-07-18

2375 Dual expansion routes likely underlie the present-day population structure in a Parnassius butterfly across the Japanese Archipelago

Tamura, H.; Noda, T.; Hayashi, M.; Fujii, Y.; Iwata, N.; Yokota, Y.; Murata, M.; Tatematsu, C.; Tera, A.; Ono, K.; Yokoi, K.; Kato, T.; Okamoto, T.; Tsuchida, K.

10.1101/2024.07.16.603823 — molecular biology — Posted on 2024-07-17

2376 Cryptic Cryptophytes-revision of the genus Goniomonas

Sachs, M.; Nitsche, F.; Arndt, H.

10.1101/2024.07.17.603845 — molecular biology — Posted on 2024-07-17

2377 Mutations in the riboflavin biosynthesis pathway confer resistance to furazolidone and abolish the synergistic interaction between furazolidone and vancomycin in Escherichia coli.

Wykes, H.; Le, V. V. H.; Rakonjac, J.

10.1101/2024.07.17.603971 — microbiology — Posted on 2024-07-17

2378 Single-strain mobilome sequencing quantifies bacterial genetic response to stress, including activity of IS elements, prophages, RNAs, and REPINs.

Nielsen, T. K.; Hansen, L. H.

10.1101/2024.07.17.603846 — microbiology — Posted on 2024-07-17

2379 The Bordetella effector protein BteA induces host cell death by disruption of calcium homeostasis

Zmuda, M.; Sedlackova, E.; Pravdova, B.; Cizkova, M.; Cerny, O.; Allsop, T. R.; Grousl, T.; Malcova, I.; Kamanova, J.

10.1101/2024.07.17.603939 — microbiology — Posted on 2024-07-17

2380 Single-cell gene-expression measurements in Vibrio cholerae biofilms reveal spatiotemporal patterns underlying development

Johnson, G. E.; Fei, C.; Wingreen, N. S.; Bassler, B. L.

10.1101/2024.07.17.603784 — microbiology — Posted on 2024-07-17

2381 Cell division protein A (CdpA) assembles and anchors the two FtsZ rings at midcell in haloarchaea

Liao, Y.; Shinde, V. D.; Hu, D.; Xu, Z.; Soderstrom, B.; Michie, K. A.; Duggin, I. G.

10.1101/2024.07.17.603854 — microbiology — Posted on 2024-07-17

2382 Northern peatland microbial networks exhibit resilience to warming and acquire electron acceptor from soil organic matter

Duchesneau, K.; Aldeguer Riquelme, B.; Petro, C.; Makke, G.; Green, M.; Tfaily, M.; Wilson, R.; Roth, S. W.; Johnston, E. R.; Kluber, L. A.; Schadt, C. W.; Chanton, J. P.; Hanson, P. J.; Tringe, S.; Eloe-Fadrosh, E.; Glavina Del Rio, T.; Konstantinidis, K. T.; Kostka, J. E.

10.1101/2024.07.17.603906 — microbiology — Posted on 2024-07-17

2383 The effect of microbial metabolites from colonic protein fermentation on bacteria-induced cytokine production in dendritic cells

Xie, Z.; Eriksen, D. B.; Johnsen, P. R.; Nielsen, D. S.; Frokiaer, H.

10.1101/2024.07.17.603665 — immunology — Posted on 2024-07-17

2384 Prkra is the double-stranded RNA sensor to mediate an embryonic integrated stress response

Lu, T.; Ma, P.; Chen, A.; Fang, H.; Xu, J.; Wang, M.; Su, L.; Wang, S.; Zhang, Y.; Wang, J.; Yang, B.; Shi, D.-L.; Zhou, Y.; Gong, Q.; Liu, X.; Mao, B.; Shao, M.

10.1101/2024.07.16.603655 — immunology — Posted on 2024-07-17

2385 Acid cleavable biotin-alkyne improves sensitivity for direct detection of biotin labeled peptides in BONCAT analysis.

McClatchy, D.; Yates, J. R.

10.1101/2024.07.16.603801 — biochemistry — Posted on 2024-07-17

2386 Proteomic evidence for amyloidogenic cross-seeding in fibrinaloid microclots

Kell, D. B.; Pretorius, E.

10.1101/2024.07.16.603837 — biochemistry — Posted on 2024-07-17

2387 PLINDER: The protein-ligand interactions dataset and evaluation resource

10.1101/2024.07.17.603955 — biochemistry — Posted on 2024-07-17

2388 Construction of mirror-image RNA nanostructure for enhanced biostability and drug delivery efficiency

Zhang, W.; Zhang, Y.; Dantsu, Y.

10.1101/2024.07.17.603907 — biochemistry — Posted on 2024-07-17

2389 The Raf/LIN-45 C-terminal distal tail segment negatively regulates signaling in Caenorhabditis elegans

Townley, R. A.; Stacy, K. S.; Cheraghi, F.; de la Cova, C. C.

10.1101/2024.07.16.603803 — genetics — Posted on 2024-07-17

2390 Image-based identification and isolation of micronucleated cells to dissect cellular consequences

DiPeso, L.; Pendyala, S.; Huang, H. Z.; Fowler, D. M.; Hatch, E. M.

10.1101/2023.05.04.539483 — cell biology — Posted on 2024-07-17

2391 Identification of novel small molecule chaperone activators for neurodegenerative disease treatment

Ho, A.; Jeganathan, F.; Bictash, M.; Whiting, P.; Chen, H.-J.

10.1101/2024.07.17.603883 — molecular biology — Posted on 2024-07-17

2392 Evolution of SARS-CoV-2 spike trimers towards optimized heparan sulfate cross-linking and inter-chain mobility

Froese, J.; Mandalari, M.; Civera, M.; Elli, S.; Pagani, I.; Vicenzi, E.; Garcia-Monge, I.; Di Iorio, D.; Frank, S.; Bisio, A.; Lenhart, D.; Gruber, R.; Yates, E. A.; Richter, R. P.; Guerrini, M.; Wegner, S. V.; Grobe, K.

10.1101/2024.07.17.603909 — molecular biology — Posted on 2024-07-17

2393 Virological characteristics of the SARS-CoV-2 KP.3.1.1 variant

Kaku, Y.; Uriu, K.; Okumura, K.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Ito, J.; Sato, K.

10.1101/2024.07.16.603835 — microbiology — Posted on 2024-07-17

2394 Equip Fusobacterium nucleatum genetic tool kits with compatible shuttle vectors and engineered intermediatory E. coli strains for enhanced transformation efficiency

Liu, L.; He, Y.; Zhang, T.; Geng, R.; Hu, Y.; Luo, M.; Zhou, H.; Liu, X.

10.1101/2024.07.17.603877 — microbiology — Posted on 2024-07-17

2395 Exploring the impact of digestive physicochemical parameters of adults and infants on the pathophysiology of Cryptosporidium parvum using the dynamic TIM-1 gastrointestinal model

Tottey, J.; Etienne-Mesmin, L.; Chalancon, S.; Sausset, A.; Denis, S.; Mazal, C.; Blavignac, C.; Salle, G.; Laurent, F.; Blanquet-Diot, S.; Lacroix-Lamande, S.

10.1101/2024.07.17.603888 — microbiology — Posted on 2024-07-17

2396 Clostridioides difficile colonization is not mediated by bile salts and requires Stickland fermentation of proline in an in vitro model of infection

Huang, X.; Johnson, A. E.; Auchtung, T. A.; McCullough, H. C.; Lerma, A. I.; Haidacher, S. J.; Hoch, K. M.; Horvath, T. D.; Haag, A.; Auchtung, J. M.

10.1101/2024.07.17.603937 — microbiology — Posted on 2024-07-17

2397 A Metagenomic Approach Does Not Elucidate Uremic Toxin Levels in Hemodialysis Patients.

Taft, D.; Quinones, J. M.; Moreno, M. L.; Fatani, A.; Suh, J.; Gorwitz, G.; Wang, Y.; Segal, M. S.; Dahl, W. J.

10.1101/2024.07.16.603811 — microbiology — Posted on 2024-07-17

2398 Evidence for infection of Eucalyptus camaldulensis with a Leifsonia bacterium in Australia and Syria using high throughput sequencing

Randles, J. W.; Hanold, D.; Baumann, U. W.; Borneman, A. R.

10.1101/2024.07.16.603836 — microbiology — Posted on 2024-07-17

2399 Seed banking alters native seed microbiome composition and function relative to natural populations

Russell, D. H.; Rajabal, V.; Alfonzetti, M.; Van der Merwe, M. M.; Gallagher, R.; Tetu, S. G.

10.1101/2024.07.16.603074 — microbiology — Posted on 2024-07-17

2400 Bacterial defense and phage counter-defense lead to coexistence in a modeled ecosystem

Kimchi, O.; Meir, Y.; Wingreen, N. S.

10.1101/2024.07.17.603905 — microbiology — Posted on 2024-07-17

2401 The catheterized bladder environment induces dysregulation of macrophage polarization exacerbating bacterial UTI

Marrufo, A. M.; Molina, J. J.; Gager, C.; Andersen, M. J.; La Bella, A. A.; Lucas, E.; Wongso, E.; Urmi, T.; Arias-Parbul, K.; Webster, R.; Stuckey, P. V.; Kohler, K. N.; Donahue, D.; Ploplis, V.; Flick, M. J.; Castellino, F. J.; Santiago-Tirado, F. H.; Flores-Mireles, A. L.

10.1101/2024.07.16.603761 — immunology — Posted on 2024-07-17

2402 F-CPI: Prediction of activity changes induced by fluorine substitution using multimodal deep learning

Zhang, Q.; Yin, W.; Chen, X.; Zhou, A.; Zhang, G.; Zhao, Z.; Li, Z.; Zhang, Y.; Shen, J.; Zhu, W.; Jiang, X.; Xu, Z.

10.1101/2024.07.17.602844 — bioinformatics — Posted on 2024-07-17

2403 Heterogeneous Slowdown of Dynamics in the Condensate of an Intrinsically Disordered Protein

Mukherjee, S.; Schäfer, L. V.

10.1101/2024.07.15.603508 — biophysics — Posted on 2024-07-17

2404 Rapid neurostimulation at micron scale with optically controlled thermal-capture technique

Romshin, A. M.; Aseyev, N.; Idzhilova, O. S.; Koryagina, A. A.; Zeeb, V. E.; Vlasov, I. I.; Balaban, P. M.

10.1101/2024.07.15.603492 — biophysics — Posted on 2024-07-17

2405 Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies

Ford, C. T.; Yasa, S.; Obeid, K.; Guirales-Medrano, S.; White, R. A.; Janies, D.

10.1101/2024.07.14.603367 — bioinformatics — Posted on 2024-07-17

2406 CompactTree: A lightweight header-only C++ library for ultra-large phylogenetics

Moshiri, N.

10.1101/2024.07.15.603593 — bioinformatics — Posted on 2024-07-17

2407 HCS-3DX, a next-generation AI-driven automated 3D high-content screening system

Diosdi, A.; Toth, T.; Grexa, I.; Schrettner, B.; Hapek, N.; Kovacs, F.; Kriston, A.; Harmati, M.; Buzas, K.; Pampaloni, F.; Piccinini, F.; Horvath, P.

10.1101/2024.07.15.603536 — bioinformatics — Posted on 2024-07-17

2408 Deep Learning-Driven Discovery of FDA-Approved BCL2 Inhibitors: In Silico Analysis Using a Deep Generative Model NeuralPlexer for Drug Repurposing in Cancer Treatment

Sayyah, E.; Tunc, H.; DURDAGI, S.

10.1101/2024.07.15.603544 — bioinformatics — Posted on 2024-07-17

2409 COLLAGE: COnsensus aLignment of muLtiplexing imAGEs

Antoranz, A.; Arnould, A.; Andhari, M. D.; Nazari, P.; Shankar, G.; De Moor, B.; De Smet, F.; Bosisio, F. M.; Pey, J.

10.1101/2024.07.15.603557 — bioinformatics — Posted on 2024-07-17

2410 Modeling Alternative Conformational States of Pseudo-Symmetric Solute Carrier Transporters using Methods from Machine Learning

Swapna, G. V. T.; Dube, N.; Roth, M. J.; Montelione, G. T.

10.1101/2024.07.15.603529 — bioinformatics — Posted on 2024-07-17

2411 Two mechanisms of photoenergy regulation revealed by kinetic behaviors of chlorophyll fluorescence during light adaptation

Chen, J.; Tan, J.; Fu, L.; Guo, Y.

10.1101/2024.07.14.603445 — bioengineering — Posted on 2024-07-17

2412 Analysis of Ground Reaction Force Impulses During Uneven Walking for Young and Older Adults

Hosseini-Yazdi, S.-S.

10.1101/2024.07.14.603453 — bioengineering — Posted on 2024-07-17

2413 Clade-specific long-read sequencing increases the accuracy and specificity of the gyrB phylogenetic marker gene

Nichols, R. G.; Davenport, E. R.

10.1101/2024.07.15.603574 — genomics — Posted on 2024-07-17

2414 Beyond A and B Compartments: how major nuclear locales define nuclear genome organization and function

Gholamalamdari, O.; van Schaik, T.; Wang, Y.; Kumar, P.; Zhang, L.; Zhang, Y.; Gonzalez, G. A. H.; Vouzas, A. E.; Zhao, P. A.; Gilbert, D. M.; Ma, J.; van Steensel, B.; Belmont, A. S.

10.1101/2024.04.23.590809 — genomics — Posted on 2024-07-17

2415 Stratifying variant deleteriousness and trait-modulating effect under human recent adaptation

Fan, X.; Huang, D.; Dong, X.; Yi, X.; Wang, J.; Zhang, S.; Dong, X.; Gu, X.; Li, M.; Sham, P. C.; Zhou, W.; Li, M. J.

10.1101/2024.07.15.603534 — genetics — Posted on 2024-07-17

2416 Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria

Jena, C.; Chinnaraj, S.; Deolankar, S.; Matange, N.

10.1101/2024.07.15.603526 — genetics — Posted on 2024-07-17

2417 Evolutionary Dynamics of Lineage-Specific Class-A GPCR Subsets Reveal Widespread Chemosensory Roles and Adaptations in Lophotrochozoa

Nath, R.; Panda, B.; Siuli, R.; Krishnan, A.

10.1101/2024.07.14.603414 — evolutionary biology — Posted on 2024-07-17

2418 Genetic Evidence for Geographic Structure within the Neanderthal Population

Rogers, A. R.

10.1101/2023.07.28.551046 — evolutionary biology — Posted on 2024-07-17

2419 Dominance hierarchies are linear but shallow in the social amoeba Dictyostelium discoideum.

Broersma, C. M. E.; Ostrowski, E. A.

10.1101/2024.07.15.602882 — evolutionary biology — Posted on 2024-07-17

2420 Heritable intraspecific variation among prey in size and movement interact to shape predation risk and potential natural selection

Coblentz, K. E.; Yang, L.; Dalal, A.; Incarnato, M. M. N.; Thilakarathne, D. D.; Shaw, C.; Wilson, R.; Biagioli, F.; Montooth, K. L.; DeLong, J. P.

10.1101/2024.01.11.575285 — ecology — Posted on 2024-07-17

2421 Fine-Scale Models of Bee Species Diversity and Habitat in New York State

Buckner, M. A.; White, E. L.; Howard, T. G.; Schlesinger, M. D.; Danforth, B. N.

10.1101/2024.07.15.603570 — ecology — Posted on 2024-07-17

2422 Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones

Dong, R.; Li, H.; He, X. C.; Wang, C.; Perera, A.; Malloy, S.; Russell, J.; Li, W.; Petentler, K.; Mao, X.; Yang, Z.; Epp, M.; Hall, K.; Scott, A.; McKinney, M. C.; Huang, S.; Smith, S.; Hembree, M.; Wang, Y.; Yu, Z.; Haug, J.; Unruh, J.; Slaughter, B.; Kang, X.; Li, L.

10.1101/2024.06.28.601225 — developmental biology — Posted on 2024-07-17

2423 UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins

Ninagawa, S.; Matsuo, M.; Ying, D.; Oshita, S.; Aso, S.; Matsushita, K.; Taniguchi, M.; Fueki, A.; Yamashiro, M.; Sugasawa, K.; Saito, S.; Imami, K.; Kizuka, Y.; Sakuma, T.; Yamamoto, T.; Yagi, H.; Kato, K.; Mori, K.

10.1101/2023.10.18.562958 — cell biology — Posted on 2024-07-17

2424 CHC22 clathrin functions in the early secretory pathway by two-site interaction with SNX5 and p115

Greig, J.; Bates, G. T.; Yin, D. I.; Briant, K.; Simonetti, B.; Cullen, P. J.; Brodsky, F. M.

10.1101/2022.12.21.520923 — cell biology — Posted on 2024-07-17

2425 Antigen-Specific modulation of MS/EAE by TCR-like Antibody Targeting Auto-Reactive Epitope

Reiter, Y.; Goor, I.; Altman, E.; Arman, I.; Haus Cohen, M.

10.1101/2024.07.15.603580 — immunology — Posted on 2024-07-17

2426 Common neural choice signals can emerge artifactually amidst multiple distinct value signals

Froemer, R.; Nassar, M. R.; Ehinger, B. V.; Shenhav, A.

10.1101/2022.08.02.502393 — neuroscience — Posted on 2024-07-17

2427 HINT1 Inhibitors as Selective Modulators of MOR-NMDAR Cross Regulation and Non-Opioid Analgesia

Dillenburg, M.; Peterson, C. D.; Dolat, R.; Ligori, K.; Kitto, K. F.; Wilcox, G. L.; Fairbanks, C. A.; Wagner, C. R.

10.1101/2024.07.15.603568 — neuroscience — Posted on 2024-07-17

2428 LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Brain Organoids

Costa, M. d. N.; Goto-Silva, L.; Nascimento, J. M.; Domith, I.; Karmirian, K.; Feilding, A.; Trindade, P.; Martins-de-Souza, D.; Rehen, S. K.

10.1101/2024.01.30.577659 — neuroscience — Posted on 2024-07-17

2429 Human Brain Barcodes

Shibata, D.

10.1101/2024.07.14.603450 — neuroscience — Posted on 2024-07-17

2430 Mistargeted retinal axons form synaptically segregated subcircuits in the visual thalamus of albino mice

McCracken, S.; McCoy, L.; Hu, Z.; Hodges, J. A.; Valkova, K.; R. Williams, P.; Morgan, J.

10.1101/2024.07.15.603571 — neuroscience — Posted on 2024-07-17

2431 Actions obey Weber's law when precision is evaluated at goal attainment

Camponogara, I.; Volcic, R.

10.1101/2024.07.15.603509 — neuroscience — Posted on 2024-07-17

2432 MELATONIN INDUCES CHANGES ON THE CIRCADIAN RHYTHMS OF REPRODUCTIVE HORMONES DURING SPERMATOGENESIS IN PUBERTAL MALE SEA BASS, Dicentrarchus labrax

Alvarado, M. V.; Espigares, F.; Carrillo, M.; Felip, A.

10.1101/2024.07.16.603757 — zoology — Posted on 2024-07-17

2433 Expanded Genome and Proteome Reallocation in a Novel, Robust Bacillus coagulans Capable of Utilizing Pentose and Hexose Sugars

Dooley, D.; Ryu, S.; Giannone, R. J.; Edwards, J.; Dien, B. S.; Slininger, P.; Trinh, C. T.

10.1101/2024.07.15.603586 — systems biology — Posted on 2024-07-17

2434 SWR1 is recruited to activated ABA response genes to maintain gene body H2A.Z in Arabidopsis thaliana

Krall, E. G.; Deal, R. B.

10.1101/2024.07.14.603444 — plant biology — Posted on 2024-07-17

2435 Convolvulaceae of Guinea: taxonomy, conservation and useful plants

Davis, B.; Couch, C.; Bidault, E.; Simbiano, F. J.; Molmou, D.; Felipe Almeida, R.; Simoes, A. R. G.

10.1101/2024.07.15.602708 — plant biology — Posted on 2024-07-17

2436 Biobased, Biodegradable but not bio-neutral: about the effects of polylactic acid nanoparticles on macrophages

Collin, V.; Vitipon, M.; Diemer, H.; CIANFERANI, S.; Darrouzet, E.; Rabilloud, T.

10.1101/2024.07.15.603484 — pharmacology and toxicology — Posted on 2024-07-17

2437 Expanded detection and impact of BAP1 alterations in cancer

Sturgill, I. R.; Raab, J. R.; Hoadley, K. A.

10.1101/2023.11.21.568094 — cancer biology — Posted on 2024-07-17

2438 Understanding the physical determinants of pressure denaturation: Temperature switches the pressure-induced unfolding pathway

Roumestand, C.; Foldeners Dudas, E.; Puglisi, R.; Calio, A.; Barthe, P.; Temussi, P. A.; Pastore, A.

10.1101/2024.07.15.603545 — biophysics — Posted on 2024-07-17

2439 Drug resistant pancreatic cancer cells exhibit altered biophysical interactions with stromal fibroblasts in imaging studies of 3D co-culture models

Struth, E.; Labaf, M.; Karimnia, V.; Liu, Y.; Cramer, G.; Dahl, J.; Slack, F. J.; Zarringhalam, K.; Celli, J.

10.1101/2024.07.14.602133 — biophysics — Posted on 2024-07-17

2440 Modeling causal signal propagation in multi-omic factor space with COSMOS

Dugourd, A.; Lafrenz, P.; Mananes, D.; Fallegger, R.; Kroger, A.-C.; Turei, D.; Shtylla, B.; Saez-Rodriguez, J.

10.1101/2024.07.15.603538 — bioinformatics — Posted on 2024-07-17

2441 Deciphering binding site conformational variability of substrate promiscuous and specialist enzymes

Thakur, D.; Verma, P.; Pandit, S. B.

10.1101/2024.07.15.603504 — bioinformatics — Posted on 2024-07-17

2442 NanoLAS 2.0: A Comprehensive Update on a Nanobody-Focused Platform with Advanced Visualization and Docking Simulation Features

Zheng, Z.; Qin, W.; Yu, K.; Hong, Y.; Tang, Y.; Wang, T.; Liang, L.; Huang, B.; Wang, X.

10.1101/2024.07.15.603553 — bioinformatics — Posted on 2024-07-17

2443 HIV-1-envelope trimer transitions from prefusion-closed to CD4-bound-open conformations through an occluded-intermediate state

Lee, M.; Lu, M.; Zhang, B.; Zhou, T.; Katte, R.; Han, Y.; Rawi, R.; Kwong, P. D.

10.1101/2024.07.15.603531 — bioinformatics — Posted on 2024-07-17

2444 Congruent timing in Human, Nightingale, Parotid Wasp and Hawaiian Planthopper vocalisations

Fourcin, A.

10.1101/2024.07.15.603552 — bioinformatics — Posted on 2024-07-17

2445 Parallelized Droplet Vitrification Enables Single-Run Vitrification of the Whole Rat Liver Hepatocyte Yield

Taggart, M. S.; Tchir, A.; Van Dieren, L.; Chen, H.; Hassan, M.; Taveras, C.; Lellouch, A. G.; Toner, M.; Sandlin, R. D.; Uygun, K.

10.1101/2024.07.14.603471 — bioengineering — Posted on 2024-07-17

2446 A Mathematical Exploration of SDH-b Loss in Chromaffin Cells

Vera-Siguenza, E.; Rana, H.; Nashiebi, R.; Cloete, I.; Kluckova, K.; Spill, F.; Tennant, D. A.

10.1101/2024.07.15.603520 — bioengineering — Posted on 2024-07-17

2447 Scalable Isolation of Surface-Engineered Extracellular Vesicles and Separation of Free Proteins via Tangential Flow Filtration and Size Exclusion Chromatography (TFF-SEC)

Kawai-Harada, Y.; Nimmagadda, V.; Harada, M.

10.1101/2024.03.07.584007 — bioengineering — Posted on 2024-07-17

2448 Deep Learning Algorithms Reveal Increased Social Activity of Rats at the Start of Evening Twilight

Popik, P.; Cyrano, E.; Golebiowska, J.; Malikowska-Racia, N.; Potasiewicz, A.; Nikiforuk, A.

10.1101/2024.07.14.603464 — animal behavior and cognition — Posted on 2024-07-17

2449 Social Status as a Latent Variable in the Amygdala of Observers of Social Interactions

Lee, S.; Rutishauser, U.; Gothard, K. M.

10.1101/2024.07.15.603487 — animal behavior and cognition — Posted on 2024-07-17

2450 Persistent, Private and Mobile genes: a model for gene dynamics in evolving pangenomes

Gamblin, J.; Lambert, A.; Blanquart, F.

10.1101/2024.07.15.603572 — evolutionary biology — Posted on 2024-07-17

2451 Growth of soil ammonia-oxidizing archaea on air-exposed solid surface.

Abiola, C.; Gwak, J.-H.; Lee, U.-J.; Awala, S. I.; Jung, M.-Y.; Park, W.; Rhee, S.-K.

10.1101/2024.07.15.603479 — ecology — Posted on 2024-07-17

2452 Effects of maize development and phenology on the field infestation dynamics of the European Corn Borer

Revillon, S.; Dillmann, C.; Galic, N.; Bauland, C.; Palaffre, C.; Malvar, R. A.; Butron, A.; Rebaudo, F.; Legrand, J.

10.1101/2024.01.29.577014 — ecology — Posted on 2024-07-17

2453 Using nature-based citizen science initiatives to enhance nature connection and mental health.

Oh, R. R. Y.; Suarez-castro, A.; Fuller, R.; Tervo, M.; Rozario, K.; Peters, B.; Chowdhury, S.; von Goenner, J.; Friedrichs-Manthey, M.; Berger, A.; Schultz, T.; Dean, A.; Tulloch, A.; Bonn, A.

10.1101/2024.07.14.603425 — ecology — Posted on 2024-07-17

2454 Generation and application of novel hES cell reporter lines for the differentiation and maturation of hPS cell-derived islet-like clusters

Zanfrini, E.; Bandral, M.; Jarc, L.; Ramirez-Torres, A. M.; Kufrin, V.; Rodriguez-Aznar, E.; Cohrs, C.; Speier, S.; Neumann, K.; Gavalas, A.

10.1101/2024.07.15.603551 — developmental biology — Posted on 2024-07-17

2455 From silence to song: Testosterone triggers extensive transcriptional changes in the female canary HVC

Ko, M.-C.; Frankl-Vilches, C.; Bakker, A.; Sohnius-Wilhelmi, N.; Alcami, P.; Gahr, M.

10.1101/2022.06.13.495861 — molecular biology — Posted on 2024-07-17

2456 Conditioned immunological memory: implication for cognition of immune cells

Zhu, Z.; Wei, Q.; Li, Q.; Zhang, H.; Lin, Z.; Chen, L.; Zhao, Y.

10.1101/2024.07.14.603476 — immunology — Posted on 2024-07-17

2457 Changes in the Public IgM Repertoire and its Idiotypic Connectivity in Alzheimer's Disease and Frontotemporal Dementia

Pashova-Dimov, S.; Petrov, P.; Karachanak-Yankova, S.; Belezhanska, D.; Zhelev, Y.; Mehrabian, S.; Traykov, L.; Pashov, A.

10.1101/2024.07.15.603559 — immunology — Posted on 2024-07-17

2458 Grape extract and resveratrol mitigate sleep fragmentation, Aβ accumulation, and abnormal neuronal excitability in a Drosophila model of Alzheimer's disease

Yu, Z.; Xu, Y.; Ping, Y.

10.1101/2024.07.14.603461 — neuroscience — Posted on 2024-07-17

2459 Loss of MEF2C function by enhancer mutation leads to neuronal mitochondria dysfunction and motor deficits in mice

Yousefian-Jazi, A.; Kim, S.; Choi, S.-H.; Chu, J.; Nguyen, P. T.-T.; Park, U.; Lim, K.; Hwang, H.; Lee, K.; Kim, Y.; Hyeon, S. J.; Rhim, H.; Ryu, H. L.; Lim, G.; Stein, T. D.; Ryu, H.; Lee, J.

10.1101/2024.07.15.603186 — neuroscience — Posted on 2024-07-17

2460 A focal traumatic injury to the spinal cord causes an immediate and massive spreading depolarization sustained by chloride ions, with transient network dysfunction and remote cortical glia changes.

Mohammadshirazi, A.; Mazzone, G. L.; Zylberberg, B. A.; Mio, L.; Pistorio, G.; Falcone, C.; Taccola, G.

10.1101/2024.07.15.603535 — neuroscience — Posted on 2024-07-17

2461 Neurophysiological correlates of cortical hierarchy across the lifespan

Fehring, J.; Balestrieri, E.; Focke, N.; Dannlowski, U.; Stier, C.; Gross, J.

10.1101/2024.07.15.602693 — neuroscience — Posted on 2024-07-17

2462 Complementary Organization of Driver and Modulator Cortico-Thalamo-Cortical Circuits

Cassidy, R. M.; Macias, A. V.; Lagos, W. N.; Ugorji, C.; Callaway, E. M.

10.1101/2024.07.14.603466 — neuroscience — Posted on 2024-07-17

2463 Criticality explains structure-function relationships in the human brain

Angiolelli, M.; Scarpetta, S.; Sorrentino, P.; Troisi Lopez, E.; Quarantelli, M.; Granata, C.; Sorrentino, G.; Palmieri, V.; Messuti, G.; Stefano, M.; Filippi, S.; Cherubini, C.; Loppini, A.; Chiodo, L.

10.1101/2024.07.15.603226 — neuroscience — Posted on 2024-07-17

2464 Insights into the foraging Gene's Influence on Mating Investments of Male Drosophila

Kim, W. J.; Li, W.; Huang, Y.

10.1101/2024.07.14.603413 — neuroscience — Posted on 2024-07-17

2465 Canonical time-series features for characterizing biologically informative dynamical patterns in fMRI

Alam, I.; Harris, B.; Cahill, P.; Cliff, O.; Markicevic, M.; Zerbi, V.; Fulcher, B. D.

10.1101/2024.07.14.603477 — neuroscience — Posted on 2024-07-17

2466 Enhancing sleep via rocking ameliorates motor behavior and reduces beta-amyloid levels in a mouse model of Alzheimer's disease

Zhang, L.; Santoni, L.; Ngo, N. A.; Simayi, R.; Ficiara, E.; de Vivo, L.; Bellesi, M.

10.1101/2024.07.15.603512 — neuroscience — Posted on 2024-07-17

2467 Large-scale Dynamical Fingerprints of Distributed Synaptic Alterations in Early-Stage Psychosis

Arazi, A.; Toso, A.; Grent-'t-Jong, T.; Uhlhaas, P. J.; Donner, T. H.

10.1101/2024.07.15.603513 — neuroscience — Posted on 2024-07-17

2468 A peptide-neurotensin conjugate that crosses the blood-brain barrier induces pharmacological hypothermia associated with anticonvulsant, neuroprotective and anti-inflammatory properties following status epilepticus in mice

Ferhat, L.; Soussi, R.; Masse, M.; Kyriatzis, G.; Girard, S.; Gassiot, F.; Gaudin, N.; Laurencin, M.; Bernard, A.; Bole, A.; Ferracci, G.; Smirnova, M.; Roman, F.; Dive, V.; Cisternino, S.; Temsamani, J.; David, M.; Lecorche, P.; Jacquot, G.; KHRESTCHATISKY, M.

10.1101/2024.07.15.603208 — neuroscience — Posted on 2024-07-17

2469 Unaware Processing of Words Activates Experience-Derived Information in Conceptual-Semantic Brain Networks

Ghio, M.; Cassone, B.; Tettamanti, M.

10.1101/2024.07.15.603501 — neuroscience — Posted on 2024-07-17

2470 Excitability modulations of somatosensory perception do not depend on feedforward neuronal population spikes

Stephani, T.; Villringer, A.; Nikulin, V.

10.1101/2024.07.15.603430 — neuroscience — Posted on 2024-07-17

2471 Oxytocin facilitates social behavior of female rats via selective modulation of interneurons in the medial prefrontal cortex

Schimmer, S.; Lefevre, A.; Lebedeva, J.; Rozov, A.; Kania, A.; Raftogianni, A.; Afordakos, K.; Tiwari, R.; Netser, S.; Patwell, R.; Hefter, D.; Boender, A.; Podpecan, Y.; Schubert, T.; Sanetra, A.; Trenk, A.; Gugula, A.; Hurlemann, R.; Althammer, F.; Blasiak, A.; Melzer, S.; Monyer, H.; Wagner, S.; Eliava, M.; Grinevich, V.

10.1101/2024.07.15.603543 — neuroscience — Posted on 2024-07-17

2472 Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles

Skiadopoulos, A.; Knikou, M.

10.1101/2024.07.15.603573 — neuroscience — Posted on 2024-07-17

2473 A Layered Microcircuit Model of Somatosensory Cortex with Three Interneuron Types and Cell-Type-Specific Short-Term Plasticity

Jiang, H.-J.; Qi, G.; Duarte, R.; Feldmeyer, D.; van Albada, S. J.

10.1101/2023.10.26.563698 — neuroscience — Posted on 2024-07-17

2474 Human gut microbiota interactions shape the long-term growth dynamics and evolutionary adaptations of Clostridioides difficile

Sulaiman, J. E.; Thompson, J.; Cheung, P. L. K.; Qian, Y.; Mill, J.; James, I.; Vivas, E.; Simcox, J.; Venturelli, O. S.

10.1101/2024.07.15.603560 — systems biology — Posted on 2024-07-17

2475 Subcellular ToF-SIMS imaging of the snow algae Sanguina nivaloides by combining high mass and high lateral resolution acquisitions

Seydoux, C.; Ezzedine, J. A.; Si Larbi, G.; Ravanel, S.; Marechal, E.; Barnes, J.-P.; Jouneau, P.-H.

10.1101/2024.07.15.603549 — plant biology — Posted on 2024-07-17

2476 Temporal profiling of the phosphate starvation response in Arabidopsis root hair cells reveals that induction of polycomb target genes does not depend on removal of H3K27me3 or H2A.Z

Holder, D. H.; Deal, R. B.

10.1101/2024.07.14.603443 — plant biology — Posted on 2024-07-17

2477 A novel repressor-activator-competitor module comprising C2H2 zinc finger and NAC transcription factors regulates rice grain development

Jaiswal, P.; Priyadarshini, R.; Yadav, A.; V, A. P.; Mahto, A.; Mathew, I.; Das, U.; Qasim, F.; Vichitra, A.; Panwar, A.; Verma, A.; Tyagi, A. K.; Agarwal, P.

10.1101/2024.07.15.603577 — plant biology — Posted on 2024-07-17

2478 Comparison of black soldier fly, cricket, and superworm on growth performance, nutrient utilization and fatty acid profiles of rainbow trout

Drosdowech, S. M.; Chiasson, M.; Ma, D.; Huyben, D.; Rooney, N.

10.1101/2024.07.15.603309 — physiology — Posted on 2024-07-17

2479 Cx43 Enhances Response to BRAF/MEK Inhibitors by Reducing DNA Repair Capacity

Varela-Vazquez, A.; Guitian-Caamano, A.; Carpintero-Fernandez, P.; Alvarez, V.; Carneiro-Figueira, A.; Varela-Eirin, M.; Calleja-Chucla, T.; Bravo, S.; Vidal, A.; Sendon-Lago, J.; Rodriguez-Candela Mateos, M.; Caeiro, J. R.; Blanco, M. G.; Sabio, G.; Rivas, C.; Santamaria, D.; Fernandez-Lozano, C.; Fonseca, E.; Huertas, P.; Sanchez-Laorden, B.; Alabert, C.; Mayan, M. D.

10.1101/2024.07.15.601645 — cancer biology — Posted on 2024-07-17

2480 CD24a knockout transforms the tumor microenvironment from cold to hot by promoting tumor-killing immune cell infiltration in a murine triple-negative breast cancer model

Chan, S.-H.; Tseng, H.-J.; Wang, L.-H.

10.1101/2024.07.15.603489 — cancer biology — Posted on 2024-07-17

2481 Simulating the growth of TAF15 inclusions in neuron soma

Kuznetsov, A. V.

10.1101/2024.07.14.603428 — biophysics — Posted on 2024-07-17

2482 Mechanism of host cell invasion by Leishmania through KMP-11 mediated cholesterol-transport and membrane phase transition

Chattopadhyay, K.; Sannigrahi, A.; Ghosh, S.; pradhan, s.; JANA, P.; Jawed, J. J.; Majumdar, S.; ROY, S.; KARMAKAR, S.; Mukherjee, B.

10.1101/2024.07.15.603533 — biophysics — Posted on 2024-07-17

2483 Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid-Liquid Phase Separated Coacervates

Tchounwou, C.; Jobanputra, A. J.; Lasher, D.; Fletcher, B. J.; Jacinto, J.; Bhaduri, A.; Best, R. L.; Fisher, W. S.; Ewert, K. K.; Li, Y.; Feinstein, S. C.; Safinya, C. R.

10.1101/2024.07.15.603342 — biophysics — Posted on 2024-07-17

2484 MALAT1 expression indicates cell quality in single-cell RNA sequencing data

Clarke, Z. A.; Bader, G.

10.1101/2024.07.14.603469 — bioinformatics — Posted on 2024-07-17

2485 Towards a Taxonomy Machine. A Training Set of 5.6 Million Arthropod Images

Steinke, D.; Ratnasingham, S.; Agda, J.; Ait Boutou, H.; Box, I.; Boyle, M.; Chan, D.; Feng, C.; Lowe, S. C.; McKeown, J. T.; McLeod, J.; Sanchez, A.; Smith, I.; Walker, S.; Wei, C. Y.-Y.; Hebert, P. D. N.

10.1101/2024.07.15.600863 — bioinformatics — Posted on 2024-07-17

2486 BMAP: a comprehensive and reproducible biomedical data analysis platform

Ren, Y.; Cheng, Z.; Li, L.; Zhang, Y.; Dai, F.; Deng, L.; Wu, Y.; Gu, J.; Lin, Q.; Wang, X.; Kong, Y.; Lu, H.

10.1101/2024.07.15.603507 — bioinformatics — Posted on 2024-07-17

2487 Optimum Push-off During Uneven Walking for Just-in-Time Strategy; Delayed Push-off Exertion is Mechanically Costly

Hosseini-Yazdi, S.-S.

10.1101/2024.07.14.603455 — bioengineering — Posted on 2024-07-17

2488 Uneven Walking Momentum Regulation Exhibit Different Strategies based on Age and State of Lookahead

Hosseini-Yazdi, S.-S.

10.1101/2024.07.14.603456 — bioengineering — Posted on 2024-07-17

2489 Neophobic response of bull ants (Myrmecia midas) to odours introduced on their foraging route

deeti, s.

10.1101/2024.07.15.603486 — animal behavior and cognition — Posted on 2024-07-17

2490 Desert ant (Melophorus bagoti) dumpers learn from experience to improve waste disposal and show spatial fidelity

deeti, s.; Cheng, K.

10.1101/2024.07.14.603462 — animal behavior and cognition — Posted on 2024-07-17

2491 Pervasive patterns in the songs of passerine birds resemble human music universals and are linked with production and cognitive mechanisms

James, L. S.; Oudyk, K.; Wall, E. M.; Chen, Y.; Pearse, W. D.; Sakata, J.

10.1101/2024.07.15.603339 — animal behavior and cognition — Posted on 2024-07-17

2492 Placental-brain axis in females detected within broadly impacted metabolic gene networks protects against prenatal PCB exposure

Chau, K.; Neier, K.; Valenzuela, A. E.; Schmidt, R. J.; Durbin-Johnson, B. P.; Lein, P. J.; Korf, I.; LaSalle, J.

10.1101/2024.07.14.603326 — genomics — Posted on 2024-07-17

2493 Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice

Chilukoti, N.; Pavuluri, S.; Kumar, S.

10.1101/2024.07.13.603037 — genetics — Posted on 2024-07-17

2494 'Disease-smart' assisted migration can enhance population fitness and increase resistance to pathogens via immune priming

Ghosh, E.; Wallace, M.; Hufbauer, R.

10.1101/2024.07.14.603437 — ecology — Posted on 2024-07-17

2495 Predicting future patterns of land cover from climate projections using machine learning

Stepinski, T.

10.1101/2024.07.14.603429 — ecology — Posted on 2024-07-17

2496 Spatial patterns of vascular plant species richness in Poland: relations among species group richness and hot spot locations

zymura, T. H.; Tegegne, H.; Szymura, M.

10.1101/2024.07.14.603435 — ecology — Posted on 2024-07-17

2497 The efficacy of the Entomopathogenic Fungus, Beauveria bassiana, in Date Palm Protection against the Red Palm Weevil, Rhynchophorus Ferrugineus, Under Hot Dessert Climate

Zer-Aviv, O.; Matveev, S.; Ment, D.

10.1101/2024.07.13.603376 — ecology — Posted on 2024-07-17

2498 FGF Signaling Regulates Development of the Anterior Fontanelle

Bobzin, L.; Nickle, A.; Ko, S.; Ince, M.; Bhojwani, A.; Merrill, A. E.

10.1101/2024.07.14.603452 — developmental biology — Posted on 2024-07-17

2499 Towards a Rosetta Stone to Decipher the Survival Networks of Senescence

Olascoaga, S.; Lopez-Diazguerrero, N. E.

10.1101/2024.07.13.603401 — cell biology — Posted on 2024-07-17

2500 HERV-derived epitopes represent new targets for T-cell based immunotherapies in ovarian cancer

Bonaventura, P.; Tabone, O.; Estornes, Y.; Page, A.; Mutez, V.; Delles, M.; Moran, S.; Dubois, C.; Lacourrege, M.; Tawfik, D.; Etchegaray, E.; Valente, A.; Boulos, R.; Jimenez Dominguez, G.; Chuvin, N.; Gadot, N.; Wang, Q.; Valladeau-Guilemond, J.; Depil, S.

10.1101/2024.07.13.603392 — immunology — Posted on 2024-07-17

2501 CyNET- a network analysis framework for high dimensionality, system level analyses of the functional Immunome

Kumar, P.; Yeo, J. G.; Poh, S. L.; Nur Hazirah, S.; Sutamam, N. B.; ang, G. W.; Chellamuthu, V. R.; Wasser, M.; Leong, J. Y.; Ramakrishna, L.; Arkachaisri, T.; Albani, S.

10.1101/2024.07.15.603495 — immunology — Posted on 2024-07-17

2502 Cell volume tunes macrophage innate inflammatory responses through promoting type I interferon signalling.

Cook, J. R.; Gleeson, T. A.; Allan, S. M.; Lawrence, C. B.; Brough, D.; Green, J. P.

10.1101/2024.07.15.603505 — immunology — Posted on 2024-07-17

2503 Dendritically localized RNAs are packaged as diversely composed Ribonucleoprotein particles with heterogeneous copy number states

Tarannum, R.; Mun, G.; Park, J.; Quddos, F.; Swanger, S. A.; Steward, O.; Farris, S.

10.1101/2024.07.13.603387 — neuroscience — Posted on 2024-07-17

2504 Taming the chaos gently: a Predictive Alignment learning rule in recurrent neural networks

Asabuki, T.; Clopath, C.

10.1101/2024.07.14.603423 — neuroscience — Posted on 2024-07-17

2505 Geometrical determinant of nonlinear synaptic integration in human cortical pyramidal neurons

Yoon, J.

10.1101/2024.07.14.601255 — neuroscience — Posted on 2024-07-17

2506 Emergence and long-term maintenance of modularity in plastic networks of spiking neurons

Bergoin, R.; Torcini, A.; Deco, G.; Quoy, M.; Zamora-Lopez, G.

10.1101/2024.07.15.603496 — neuroscience — Posted on 2024-07-17

2507 Peripheral CaV2.2 channels in skin regulate prolonged heat hypersensitivity during neuroinflammation

Salib, A.-M. N.; Crane, M. J.; Jamieson, A. M.; Lipscombe, D.

10.1101/2024.07.13.603149 — neuroscience — Posted on 2024-07-17

2508 Induction of long-term hyperexcitability by memory-related cAMP signaling in isolated nociceptor cell bodies

Bavencoffe, A.; Zhu, M. Y.; Neerukonda, S. V.; Johnson, K. N.; Dessauer, C. W.; Walters, E. T.

10.1101/2024.07.13.603393 — neuroscience — Posted on 2024-07-17

2509 The barley MLA13-AVRA13 heterodimer reveals principles for immunoreceptor recognition of RNase-like powdery mildew effectors

Lawson, A. W.; Flores-Ibarra, A.; Cao, Y.; An, C.; Neumann, U.; Gunkel, M.; Saur, I. M. L.; Chai, J.; Behrmann, E.; Schulze-Lefert, P.

10.1101/2024.07.14.603419 — plant biology — Posted on 2024-07-17

2510 OPTIMIZATION OF RECOVERABLE CLEAR PLASTIC POT (rCPP) METHOD AND VALIDATION OF MOLECULAR MARKS FOR THE SCREENING OF DEEP ROOTING OF RICE (Oryza sativa L.)

pratama, m. s.; basunanda, p.; wulandari, r. a.; Widyawan, M. H.

10.1101/2024.07.14.603442 — plant biology — Posted on 2024-07-17

2511 Stretching the structural envelope of isomeric imatinib analogs that reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

Netzer, W. J.; Sinha, A.; Ghias, M.; Chang, E.; Gindinova, K.; Mui, E.; Seo, J.-S.; Sinha, S.

10.1101/2024.07.14.602669 — pharmacology and toxicology — Posted on 2024-07-17

2512 Moderate-term dimethyl fumarate treatment reduces pathology of dystrophic skeletal and cardiac muscle in a mouse model

Kourakis, S.; Timpani, C. A.; Bagaric, R. M.; Qi, B.; Ali, B. A.; Boyer, R.; Spiesberger, G.; Kandhari, N.; Peterson, A. L.; Debrincat, D.; Yates, T. J.; Yan, X.; Stupka, N.; Kuang, J.; Nijagal, B.; Deveson-Lucas, D.; Fischer, D.; Rybalka, E.

10.1101/2024.07.13.601627 — pathology — Posted on 2024-07-17

2513 Oncogene inactivation-induced senescence facilitates tumor relapse

Schmitt, P.; Hoenig, K.; Milojkovic, A.; Anders, K.; Schroeck, E.; Sauer, S.; Uyar, B.; Akalin, A.; Martinez-Reyes, I.; Blankenstein, T.

10.1101/2024.07.13.603369 — cancer biology — Posted on 2024-07-17

2514 Targeting fatty acid synthase suppresses tumor development in NF2/CDKN2A-deficient malignant pleural mesothelioma

Karnan, S.; OTA, A.; Hasan, M. N.; Murakami, H.; Rahman, M. L.; Wahiduzzaman, M.; Shihan, M. T. A. S. T. A.; Jahan, N.; Vu, L. Q.; Hanamura, I.; Inoko, A.; Riku, M.; Ito, H.; Kaneko, Y.; Lin, Y.; Hyodo, T.; Konishi, H.; Tsuzuki, S.; Hosokawa, Y. H.

10.1101/2024.07.14.603191 — cancer biology — Posted on 2024-07-17

2515 Protein-Induced Membrane Strain Drives Supercomplex Formation

Poverlein, M. C.; Jussupow, A.; Kim, H.; Kaila, V. R. I.

10.1101/2024.07.13.602826 — biophysics — Posted on 2024-07-17

2516 Reversible disulfide bond crosslinks as tunable levers of phase separation in designer biomolecular condensates.

Mondal, M.; Jankoski, P. E.; Lee, L. D.; Dinakarapandian, D. M.; Chiu, T.-Y.; Swetman, W. S.; Wu, H.; Paravastu, A. K.; Clemons, T. D.; Rangachari, V.

10.1101/2024.07.13.603402 — biophysics — Posted on 2024-07-17

2517 Adaptive Regularized Tri-Factor Non-Negative Matrix Factorization for Cell Type Deconvolution

Liu, T.; Liu, C.; Li, Q.; Zheng, X.; Zou, F.

10.1101/2023.12.07.570631 — bioinformatics — Posted on 2024-07-17

2518 RFMix-reader: Accelerated reading and processing for local ancestry studies

Benjamin, K. J. M.

10.1101/2024.07.13.603370 — bioinformatics — Posted on 2024-07-17

2519 Large-Scale Computational Modeling of H5 Influenza Variants Against HA1-Neutralizing Antibodies

Ford, C. T.; Yasa, S.; Obeid, K.; Guirales-Medrano, S.; White, R. A.; Janies, D.

10.1101/2024.07.14.603367 — bioinformatics — Posted on 2024-07-17

2520 Towards Reliable Diabetes Prediction: Innovations in Data Engineering and Machine Learning Applications

Talukder, M. A.; Islam, M. M.; Uddin, M. A.; Kazi, M.; Khalid, M.; Akhter, A.; Moni, M. A.

10.1101/2024.07.14.603436 — bioinformatics — Posted on 2024-07-17

2521 Experience improves navigational knowledge of dumpers in desert ants (Melophorus bagoti)

deeti, s.

10.1101/2024.07.14.603463 — animal behavior and cognition — Posted on 2024-07-17

2522 Chromosome-level genome assembly and annotation of Corallium rubrum: a Mediterranean coral threatened by overharvesting and climate change.

Ledoux, J.-B.; Gomez-Garrido, J.; Cruz, F.; Camara, F.; Matos, A.; Sarropoulou, X.; Ramirez-Calero, S.; Aurelle, D.; Lopez-Sendino, P.; Grayson, N.; Moore, B.; Antunes, A.; Aguilera, L.; Gut, M.; Salces-Ortiz, J.; Fernandez, R.; Linares, C.; Garrabou, J.; Alioto, T.

10.1101/2024.07.13.603384 — genomics — Posted on 2024-07-17

2523 Many erroneous noncoding transcripts in cancer cells can highly specifically regulate cancer-related genes and pathways

He, S.; Xiong, W.; Huo, J.; Lin, J.; Li, J.; Zhu, H.

10.1101/2024.07.13.603398 — genomics — Posted on 2024-07-17

2524 eDNA metabarcoding shows highly diverse but distinct shallow, mid-water, and deep-water eukaryotic communities within a marine biodiversity hotspot

Cerrillo-Espinosa, P.; Calderon-Aguilera, L. E.; Medina-Rosas, P.; Gomez-Gutierrez, J.; Reyes-Bonilla, H.; Cupul-Magana, A.; Gonzalez-Cuellar, O. T.; Munguia-Vega, A.

10.1101/2024.07.14.603441 — genomics — Posted on 2024-07-17

2525 The evolutionary cost of homophily: social stratification facilitates stable variant coexistence and increased rates of evolution in host-associated pathogens

Li, S.; Gulisija, D.; Carja, O.

10.1101/2024.07.14.603415 — evolutionary biology — Posted on 2024-07-17

2526 Maintenance of long-term transposable element activity in genomes through regulation by nonautonomous elements

Omole, A. D.; Czuppon, P.

10.1101/2024.07.13.603364 — evolutionary biology — Posted on 2024-07-17

2527 Dynamical forces drive organ morphology changes during embryonic development

Manna, R. K.; Retzlaff, E. M.; Hinman, A. M.; Lan, Y.; Abdel-Razek, O.; Bates, M.; Hehnly, H.; Amack, J. D.; Manning, M. L.

10.1101/2024.07.13.603371 — developmental biology — Posted on 2024-07-17

2528 Cortical layer-specific and cell type-specific dendritic expression of Arc (Arg 3.1) in an in vitro model of slow-wave sleep

Hartnell, I. J.; Simon, A.; Hall, S. P.; Ducotterd, F.; Whittington, M. A.; Chawla, S.

10.1101/2024.07.17.603872 — neuroscience — Posted on 2024-07-17

2529 ACID: A Comprehensive Toolbox for Image Processing and Modeling of Brain, Spinal Cord, and Post-mortem Diffusion MRI Data

David, G.; Fricke, B.; Oeschger, J. M.; Ruthotto, L.; Fritz, F. J.; Ohana, O.; Mordhorst, L.; Sauvigny, T.; Freund, P.; Tabelow, K.; Mohammadi, S.

10.1101/2023.10.13.562027 — neuroscience — Posted on 2024-07-17

2530 Thermodynamics of unicellular life: Entropy production rate as function of the balanced growth rate

Droste, M. J.; Remeijer, M.; Planque, R.; Bruggeman, F. J.

10.1101/2024.07.13.603363 — systems biology — Posted on 2024-07-17

2531 Mangrove endophytes shorten the life cycle of rice while enhancing yield and salt tolerance

Alghamdi, A.; Rawat, A. R.; Nagajaran, A. P.; Parween, S.; Saad, M. M.; Hirt, H.

10.1101/2024.07.12.603329 — plant biology — Posted on 2024-07-17

2532 Rubisco from two ecotypes of Plantago lanceolata L. that are native to sites differing in atmospheric CO2 levels

Shi, X.; Hannon, N. M.; Bloom, A. J.

10.1101/2024.07.13.603406 — plant biology — Posted on 2024-07-17

2533 JAK2/STAT3 signaling pathway mediates methylmercury toxicity in mouse astrocyte neuronal C8-D1A cell line

Ahmed, A.; Aschner, M.; Ferrer, B.

10.1101/2024.07.13.603400 — pharmacology and toxicology — Posted on 2024-07-17

2534 B cell receptor silencing reveals the origin of high-grade B cell lymphomas with MYC and BCL2 rearrangements

Sindaco, P.; Lonardi, S.; Varano, G.; Pietrini, I.; Morello, G.; Balzarini, P.; Neuman, H.; Vit, F.; Bertolazzi, G.; Arima, H.; Chiarini, M.; Lorenzi, L.; Pellegrini, V.; Giampaolo, S.; Garzon, D.; Ranise, C.; Bugatti, M.; Pagani, C.; Daffini, R.; Mainoldi, F.; Selvarasa, V.; Sivacegaram, A.; Yang, H.; Ying, L.; Cancila, V.; Bonnal, R.; Visco, E.; Gonzalez, C. L.; Capaccio, P.; Ferreri, A. J. M.; Tucci, A.; Cabras, A. D.; Pruneri, G.; di Napoli, A.; Siebert, R.; Bomben, R.; Falini, B.; Pizzi, M.; Song, J. Y.; Chan, W. C.; Ponzoni, M.; Mehr, R.; Tripodo, C.; Facchetti, F.; Casola, S.

10.1101/2024.07.13.603066 — cancer biology — Posted on 2024-07-17

2535 Marker Data Enhancement For Markerless Motion Capture

Falisse, A.; Uhlrich, S.; Chaudhari, A.; Hicks, J.; Delp, S.

10.1101/2024.07.13.603382 — bioengineering — Posted on 2024-07-17

2536 Targeting CD19 for the treatment of autoimmune with a novel T cell engager

Yuan, A. Q.; Zhao, L.; Bai, L.; Wang, Y.; Yang, I.; Yuan, R. Q.; Meng, Q.; Dai, X.

10.1101/2024.02.17.580750 — immunology — Posted on 2024-07-17

2537 ApoE ε4-dependent alteration of CXCR3+CD127+ CD4+ T cells is associated with elevated plasma neurofilament light chain in Alzheimer's disease

Hu, D.; Chen, M.; Li, X.; Morin, P.; Daley, S.; Han, Y.; Hemberg, M.; Weiner, H. L.; Xia, W.

10.1101/2024.05.28.596276 — immunology — Posted on 2024-07-17

2538 Transcriptomic analysis of the human habenula in schizophrenia

Yalcinbas, E. A.; Ajanaku, B.; Nelson, E. D.; Garcia-Flores, R.; Eagles, N. J.; Montgomery, K. D.; Stolz, J. M.; Wu, J.; Divecha, H. R.; Chandra, A.; Bharadwaj, R.; Bach, S.; Rajpurohit, A.; Tao, R.; Pertea, G.; Shin, J.-H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. R.; Huuki-Myers, L. A.; Collado-Torres, L.; Maynard, K. R.

10.1101/2024.02.26.582081 — neuroscience — Posted on 2024-07-17

2539 Interpretably deep learning amyloid nucleation by massive experimental quantification of random sequences

Thompson, M.; Martin, M.; Olmo, T. S.; Rajesh, C.; Koo, P.; Bolognesi, B.; Lehner, B.

10.1101/2024.07.13.603366 — genomics — Posted on 2024-07-17

2540 PhotoFiTT: A Quantitative Framework for Assessing Phototoxicity in Live-Cell Microscopy Experiments

Del Rosario, M.; Gomez-de-Mariscal, E.; Morgado, L.; Portela, R.; Jacquemet, G.; Pereira, P. M.; Henriques, R.

10.1101/2024.07.16.603046 — cell biology — Posted on 2024-07-17

2541 Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project

Emma, R.; Sun, A.; Partsinevelos, K.; Rust, S.; Volarevic, V.; Lesmana, R.; Giordano, A.; Goenawan, H.; Barliana, M. I.; Arsenijevic, A.; Kastratovic, N.; Markovic, V.; Spasic, B.; Distefano, A.; Orlando, L.; Carota, G.; Polosa, R.; Caruso, M.; Li Volti, G.

10.1101/2024.01.20.576442 — pharmacology and toxicology — Posted on 2024-07-17

2542 Androgen receptor plays critical role in regulating cervical cancer cell migration

Bose, S.; Das, S.; Maity, S.; Chakrabarti, O.; Chakrabarti, S.

10.1101/2024.07.13.603408 — cancer biology — Posted on 2024-07-17

2543 Identifying maximally informative signal-aware representations of single-cell data using the Information Bottleneck

Dubnov, S.; Piran, Z.; Soreq, H.; Nitzan, M.

10.1101/2024.05.22.595292 — bioinformatics — Posted on 2024-07-17

2544 Proxi-RIMS-seq2 applied to native microbiomes uncovers hundreds of known and novel m5C methyltransferase specificities.

Yang, W.; Luyten, Y.; Reister, E.; Mangelson, H.; Sisson, Z.; Auch, B.; Liachko, I.; Roberts, R. J.; Ettwiller, L.

10.1101/2024.07.15.603628 — genomics — Posted on 2024-07-17

2545 Evolution of phenotypic plasticity during environmental fluctuations

Sekajova, Z.; Fossen, E. I. F.; Rosa, E.; Ratikainen, I. I.; Tourniaire-Blum, M.; Bolund, E.; Lind, M. I.

10.1101/2023.01.22.523389 — evolutionary biology — Posted on 2024-07-17

2546 TNFR2 loss leads to decreased TOX expression in T cells without affecting TIM3 and improves responses to tumor and chronic LCMV

Hoyt-Miggelbrink, A.; Waibl Polania, J.; Wachsmuth, L.; Lorrey, S. J.; Mohan, A.; Hardigan, A. A.; Blandford, E.; Lerner, E.; Wilkinson, D.; Hotchkiss, K.; Cook, S.; Hemmers, S.; Patel, A.; Ayasoufi, K.; Fecci, P. E.

10.1101/2024.07.12.603311 — immunology — Posted on 2024-07-17

2547 Using an ODE model to separate Rest and Task signals in fMRI

Kashyap, A.; Geenjaar, E. P. T.; Bey, P.; Dhindsa, J.; Glomb, K.; Plis, S.; Keilholz, S.; Ritter, P.

10.1101/2023.10.23.563564 — neuroscience — Posted on 2024-07-17

2548 Associative plasticity of granule cell inputs to cerebellar Purkinje cells.

Conti, R.; Auger, C.

10.1101/2023.03.06.531306 — neuroscience — Posted on 2024-07-17

2549 Homeostatic Synaptic Plasticity of Miniature Excitatory Postsynaptic Currents in Mouse Cortical Cultures Requires Neuronal Rab3A.

Koesters, A. G.; Rich, M. M.; Engisch, K. L.

10.1101/2023.06.14.544980 — neuroscience — Posted on 2024-07-17

2550 Impaired baroreceptor reflex sensitivity in pelvic suspension rats is associated with sympathovagal imbalance but not with carotid artery structural change

Bhatnaagar, A.; Deepak, K. K.; Roy, A.; Anil, A. K.; Sharma, B.; Singh, A.; Netam, R.

10.1101/2022.09.02.506352 — physiology — Posted on 2024-07-17

2551 Engineering PEG10 assembled endogenous virus-like particles with genetically encoded neoantigen peptides for cancer vaccination

Tang, R.; Guo, L.; Wei, T.; Chen, T.; Yang, H.; Ye, H.; Lin, F.; Zeng, Y.; Yu, H.; Cai, Z.; Liu, X.

10.1101/2024.04.25.591213 — cancer biology — Posted on 2024-07-17

2552 Context-dependent structure formation of hairpin motifs in bacteriophage MS2 genomic RNA

Bukina, V.; Bozic, A.

10.1101/2024.04.17.589867 — biophysics — Posted on 2024-07-17

2553 Amyloid-β can activate JNK signalling via WNT-5A/ROR2 to reduce synapse formation in Alzheimer's disease.

Scholpp, S.; Fang, K.; Pishva, E.; Piers, T.

10.1101/2024.07.16.603668 — cell biology — Posted on 2024-07-17

2554 Human FASTK preferentially binds single-stranded and G-rich RNA

Dawidziak, D. M.; Dzadz, D. A.; Kuska, M. I.; Kanavalli, M.; Klimecka, M. M.; Merski, M.; Bandyra, K. J.; Gorna, M. W.

10.1101/2024.07.16.603671 — molecular biology — Posted on 2024-07-17

2555 Antibody-dependent DENV infection induces distinct transcriptomic responses in infected and bystander human macrophages

Hardy, C. S. C.; Wegman, A. D.; Waldran, M. J.; Waickman, A.

10.1101/2024.07.11.603036 — immunology — Posted on 2024-07-17

2556 Dietary Branched Chain Amino Acids Modify Post-Infarct Cardiac Remodeling and Function in the Murine Heart

Nguyen, D. C.; Wells, C. K.; Taylor, M. S.; Martinez-Ondaro, Y. R.; Brittian, K. R.; Brainard, R. E.; Moore, J. B.; Hill, B. G.

10.1101/2024.07.12.603348 — physiology — Posted on 2024-07-17

2557 Carbon Dots and Single-walled Carbon Nanotubes Enhances Maize Shading Stress Tolerance

Khan, M. N.; Ali, W.; Grillo, R.; Wu, H.; Nie, L.

10.1101/2024.07.11.603111 — physiology — Posted on 2024-07-17

2558 CompareM2 is a genomes-to-report pipeline for comparing microbial genomes

Kobel, C. M.; Aho, V. T. E.; Oyas, O.; Norskov-Lauritsen, N.; Woodcroft, B. J.; Pope, P. B.

10.1101/2024.07.12.603264 — bioinformatics — Posted on 2024-07-17

2559 Toward industrial C8 production: Oxygen intrusion drives renewable n caprylate production from ethanol and acetate via intermediate metabolite production

Gemeinhardt, K.; Seung Jeon, B.; Nepomuscene Ntihuga, J.; Wang, H.; Schlaiss, C.; Lucas, T. N.; Bessarab, I.; Nalpas, N. C.; Zhou, N.; Usack, J. G.; Huson, D.; Williams, R.; Macek, B.; Aristilde, L.; Angenent, L. T.

10.1101/2024.07.12.603245 — bioengineering — Posted on 2024-07-17

2560 Comprehensive elucidation of glutathione import in Escherichia coli

Knoke, L. R.; Muskietorz, M.; Kühn, L.; Leichert, L. I.

10.1101/2024.07.15.603537 — biochemistry — Posted on 2024-07-17

2561 Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe

stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.

10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-07-17

2562 Diverse fox circovirus (Circovirus canine) variants circulate at high prevalence in grey wolves (Canis lupus) from the Northwest Territories, Canada

Canuti, M.; King, A. V. L.; Franzo, G.; Cluff, H. D.; Larsen, L. E.; Fenton, H.; Dufour, S. C.; Lang, A. S.

10.1101/2024.03.08.584028 — microbiology — Posted on 2024-07-17

2563 Muller glia cell cycle re-activation by simultaneous cyclin D1 overexpression and p27kip1 knockdown promotes retinal regeneration in mice

Wu, Z.; Liao, B.; Ying, J.; Keung, J.; Zheng, Z.; Ahola, V.; Xiong, W.

10.1101/2024.07.12.603194 — neuroscience — Posted on 2024-07-17

2564 High fat diet induces differential age- and gender-dependent changes in neuronal function linked to redox stress.

de Lange, M.; Yarosh, V.; Farel, K.; Oates, C.; Patil, R.; Hawthorn, I.; Jung, M.-M.; Wenje, S.; Steinert, J. R.

10.1101/2024.07.12.603123 — neuroscience — Posted on 2024-07-17

2565 Leading researchers in the leadership of leading research universities: meta-research analysis

Ioannidis, J.

10.1101/2024.04.02.587840 — scientific communication and education — Posted on 2024-07-17

2566 Daily rhythms in metabolic and locomotor behaviour of prematurely ageing PolgA mice

Mueller, R.; Singh, A.; Kuhn, G. A.; Wehrle, E.; Yilmaz, D.

10.1101/2024.03.27.586233 — physiology — Posted on 2024-07-17

2567 Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates

Uckelmann, M.; Levina, V.; Taveneau, C.; Ng, X. H.; Pandey, V.; Martinez, J.; Mendiratta, S.; Houx, J.; Boudes, M.; Venugopal, H.; Trepout, S.; Zhang, Q.; Flanigan, S.; Li, M.; Sierecki, E.; Gambin, Y.; Das, P. P.; Bell, O.; de Marco, A.; Davidovich, C.

10.1101/2023.05.08.539931 — biophysics — Posted on 2024-07-17

2568 An emerging view of neural geometry in motor cortex supports high-performance decoding

Perkins, S. M.; Amematsro, E. A.; Cunningham, J. P.; Wang, Q.; Churchland, M. M.

10.1101/2023.04.05.535396 — bioengineering — Posted on 2024-07-17

2569 Inherited CDA-I disease: anemia-associated mutations disrupt CDIN1-Codanin1 complex

Stojaspal, M.; Brom, T.; Janovic, T.; Necasova, I.; Veverka, P.; Uhrik, L.; Hernychova, L.; Hofr, C.

10.1101/2023.05.25.542057 — biochemistry — Posted on 2024-07-17

2570 Phosphorylation-induced flexibility of proto-oncogenic Bcl3 regulates transcriptional activation by NF-κB p52 homodimer

Pan, W.; Biswas, T.; Shahabi, S.; Suryajaya, W.; Vasquez, A.; Du, Q.; Ghosh, G.; Wang, V. Y.-F.

10.1101/2024.06.30.601400 — biochemistry — Posted on 2024-07-17

2571 Actin dynamics sustains spatial gradients of membrane tension in adherent cells

Garcia-Arcos, J. M.; Mehidi, A.; Sanchez Velazquez, J.; Guillamat, P.; Tomba, C.; Houzet, L.; Capolupo, L.; D'Angelo, G.; Colom, A.; Hinde, E.; Aumeier, C.; Roux, A.

10.1101/2024.07.15.603517 — cell biology — Posted on 2024-07-17

2572 Parvalbumin Neurons and Cortical Coding of Dynamic Stimuli: A Network Model

Nocon, J. C.; Boyd, I. P.; Gritton, H.; Han, X.; Sen, K.

10.1101/2022.09.22.509092 — neuroscience — Posted on 2024-07-17

2573 Can biocrust moss hide from climate change? Fine-scale habitat sheltering improves summer-stress resistance in Syntrichia caninervis

Clark, T. A.; Russell, A.; Greenwood, J. L.; Devitt, D.; Stanton, D.; Stark, L. R.

10.1101/2023.11.06.565694 — plant biology — Posted on 2024-07-17

2574 Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation

Shaw, J. B.; Harvey, S. R.; Du, C.; Xu, Z.; Edgington, R. M.; Olmedillas, E.; Saphire, E. O.; Wysocki, V. H.

10.1101/2024.03.07.583498 — biophysics — Posted on 2024-07-17

2575 Mutational and evolutionary dynamics of non-structural and spike proteins from variants of concern (VOC) ofSARS-CoV-2 in India

Chaudhuri, A.; Das, S.; Chakrabarti, S.

10.1101/2024.07.14.603481 — bioinformatics — Posted on 2024-07-17

2576 PhotoFiTT: A Quantitative Framework for Assessing Phototoxicity in Live-Cell Microscopy Experiments

Del Rosario, M.; Gomez-de-Mariscal, E.; Morgado, L.; Portela, R.; Jacquemet, G.; Pereira, P. M.; Henriques, R.

10.1101/2024.07.16.603046 — cell biology — Posted on 2024-07-16

2577 Condensation of PRPP amidotransferase by phase separation promotes de novo purine synthesis through intermolecular intermediate channeling in yeast

Takaine, M.; Morita, R.; Yoshinari, Y.; Nishimura, T.

10.1101/2023.06.05.543815 — cell biology — Posted on 2024-07-17

2578 Sub-nucleolar trafficking of Hendra virus matrix protein is regulated by ubiquitination and oligomerisation

Rawlinson, S. M.; Zhao, T.; Gomez, F. A.; David, C. T.; Rootes, C. L.; Veuglers, P. F.; Rozario, A. M.; Stewart, C. R.; Bell, T. D. M.; Moseley, G. W.

10.1101/2023.08.10.552741 — microbiology — Posted on 2024-07-17

2579 Application of mechanistic multiparameter optimization and large scale in vitro to in vivo pharmacokinetics correlations to small molecule therapeutic projects

Broccatelli, F.; Veeravalli, V.; Cashion, D.; Baylon, J. L.; Lombardo, F.; Jia, L.

10.1101/2024.03.06.583780 — pharmacology and toxicology — Posted on 2024-07-17

2580 Vesicle Picker: A tool for efficient identification of membrane protein complexes in vesicles

Karimi, R.; Coupland, C. E.; Rubinstein, J. L.

10.1101/2024.07.15.603622 — biophysics — Posted on 2024-07-16

2581 On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation

Krokengen, O. C.; Raasakka, A.; Klenow, M. B.; Pal, A.; Hetland, O.; Mularski, A.; Ruskamo, S.; Pedersen, J. S.; Simonsen, A. C.; Kursula, P.

10.1101/2024.07.15.603506 — biochemistry — Posted on 2024-07-16

2582 Comprehensive elucidation of glutathione import in Escherichia coli

Knoke, L. R.; Muskietorz, M.; Lupilov, N.; Leichert, L. I.

10.1101/2024.07.15.603537 — biochemistry — Posted on 2024-07-16

2583 Structure of human PIEZO1 and its slow inactivating channelopathy mutants

Shan, Y.; Guo, X.; Zhang, M.; Chen, M.; Li, Y.; Zhang, M.; Pei, D.

10.1101/2024.07.14.603468 — biochemistry — Posted on 2024-07-16

2584 Proteomic analysis identifies dysregulated proteins in albuminuria: a South African pilot study

Khoza, S.; George, J. A.; Naicker, P.; Stoychev, S. H.; Fabian, J.; Govender, I. S.

10.1101/2024.07.16.603438 — biochemistry — Posted on 2024-07-16

2585 Stabilised D2R G-protein coupled receptor oligomers identify multi-state β-arrestin complexes

Sharrocks, K. L.; Fanelli, F.; Milner, A. J.; Lui, Y.; Yining, W.; Byrne, B.; Hanyaloglu, A.

10.1101/2024.07.16.603735 — cell biology — Posted on 2024-07-16

2586 Polymer physics models reveal structural folding features of single-molecule gene chromatin conformations

Conte, M.; Abraham, A.; Esposito, A.; Yang, L.; Gibcus, J. H.; Parsi, K. M.; Vercellone, F.; Fontana, A.; Di Pierno, F.; Dekker, J.; Nicodemi, M.

10.1101/2024.07.16.603769 — molecular biology — Posted on 2024-07-16

2587 In vitro evolution of ciprofloxacin resistance in Neisseria commensals and derived mutation population dynamics in natural Neisseria populations

Robinson, L. R.; Mcdevitt, C. J.; Reagen, M. R.; Quail, S. L.; Wadsworth, C. B.

10.1101/2024.07.16.603762 — microbiology — Posted on 2024-07-16

2588 Acinetobacter baumannii DacC influences cell shape, biofilm formation, and physiological fitness by manifesting DD-carboxypeptidase and β-lactamase dual-enzyme activities

Pal, S.; Jain, D.; Biswal, S.; Rastogi, S. K.; Kumar, G.; Ghosh, A. S.

10.1101/2024.07.16.603720 — microbiology — Posted on 2024-07-16

2589 P-BODY AND CYTOSKELETON REMODELING BY ORTHOHANTAVIRUSES.

Schwarzer-Sperber, H. S.; Petrich, A.; Schade, M.; Nilson, N.; Chibrac-Ahad, L.; Lehmann, M. J.; Paulick, K.; Weiss, S.; Bourquain, D.; Witkowski, P. T.; Krüger, D. H.; Herrmann, A.; Schwarzer, R.

10.1101/2024.07.16.603662 — microbiology — Posted on 2024-07-16

2590 A multiscale model of the action of a capsid assembly modulator for the treatment of chronic hepatitis B

Iyaniwura, S.; Cassidy, T.; Ribeiro, R. M.; Perelson, A. S.

10.1101/2024.07.16.603658 — microbiology — Posted on 2024-07-16

2591 The stress-protectant molecule trehalose mediates fluconazole tolerance in Candida glabrata

Zhu, Q.; Wijnants, S.; Feil, R.; Vergauwen, R.; Lunn, J. E.; Van Ende, M.; Van Dijck, P.

10.1101/2024.07.16.603661 — microbiology — Posted on 2024-07-16

2592 Chemical inactivation of two non-enveloped viruses follows distinct molecular pathways

Narula, P.; Lokshman, M. K.; Pathak, S. B.; Mukherjee, S.; Banerjee, M.

10.1101/2024.07.16.603687 — microbiology — Posted on 2024-07-16

2593 Competition and interdependence define multifaceted interactions of symbiotic Nostoc sp. and Agrobacterium sp. under inorganic carbon limitation

Teikari, J. E.; Russo, D. A.; Heuser, M.; Baumann, O.; Zedler, J. A. Z.; Liaimer, A.; Dittmann, E.

10.1101/2024.07.16.603663 — microbiology — Posted on 2024-07-16

2594 An essential role for the Hv1 voltage-gated proton channel in Pseudomonas aeruginosa corneal infection

Rodriguez, P.; Abbondante, S.; Marshall, M. M.; Abdelmeseh, J.; Tombola, F.; Pearlman, E.

10.1101/2024.07.15.603631 — microbiology — Posted on 2024-07-16

2595 Systematically investigating and identifying unmodified bacteriocins in the human gut microbiome

Zhang, D.; Shi, Y.; Zhang, J.; Liu, J.; Wu, G.; Zhang, J.; Gao, Y.; LI, Y.-X.

10.1101/2024.07.15.603639 — microbiology — Posted on 2024-07-16

2596 Chlamydia muridarum Causes Persistent Subclinical Infection and Elicits Innate and Adaptive Immune Responses in C57BL/6J, BALB/cJ and J:ARC(S) Mice Following Exposure to Shedding Mice

Mishkin, N.; Carrasco, S. E.; Palillo, M. B.; Momtsios, P.; Woods, C.; Henderson, K. S.; Longhini, A. L. F.; Otis, C.; Gardner, R.; Joseph, A. M.; Sonnenberg, G. F.; Palillo, J.; Ricart Arbona, R. J.; Lipman, N. S.

10.1101/2024.07.16.603732 — microbiology — Posted on 2024-07-16

2597 Peptide-enabled ribonucleoprotein delivery for CRISPR engineering (PERC) in primary human immune cells and hematopoietic stem cells

Sahu, S.; Castro, M.; Muldoon, J. J.; Asija, K.; Wyman, S. K.; Krishnappa, N.; Eyquem, J.; Nguyen, D. N.; Wilson, R. C.

10.1101/2024.07.14.603391 — bioengineering — Posted on 2024-07-16

2598 Allosteric regulation of the tyrosine phosphatase PTP1B by a protein-protein interaction

Chartier, C. A.; Woods, V. A.; Xu, Y.; van Vlimmeren, A. E.; Jovanovic, M.; McDermott, A. E.; Keedy, D. A.; Shah, N. H.

10.1101/2024.07.16.603632 — biochemistry — Posted on 2024-07-16

2599 SlNAP2 promoted fruit ripening by directly binding the ACS2 promoter and interacting with EIL3

Wu, X.; Fang, H.; Huang, D.; Hou, X.; Qiao, Y.; Li, C.; Li, A.; Huang, Y.; Zhang, Z.; Liu, Z.; Liu, Y.; Liao, W.

10.1101/2024.07.15.603576 — biochemistry — Posted on 2024-07-16

2600 Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin

Carver, A.; Yu, T.-Y.; Yates, L.; White, T.; Wang, R.; Lister, K.; Jasin, M.; Zhang, X.

10.1101/2024.07.16.603765 — biochemistry — Posted on 2024-07-16

2601 Diffusing protein binders to intrinsically disordered proteins

Liu, C.; Wu, K.; Choi, H.; Han, H.; Zhang, X.; Watson, J. L.; Shijo, S.; Bera, A. K.; Kang, A.; Brackenbrough, E.; Coventry, B.; Hick, D. R.; Hoofnagle, A. N.; Zhu, P.; Li, X.; Decarreau, J.; Gerben, S. R.; Yang, W.; Wang, X.; Lamp, M.; Murray, A.; Bauer, M.; Baker, D.

10.1101/2024.07.16.603789 — biochemistry — Posted on 2024-07-16

2602 Titration-WB: A methodology for accurate quantitative protein determination overcoming reproducibility errors

Maestri, A.; Ehrenborg, E.; Werngren, O.; Olin, M.; Hagberg, C. E.; Pedrelli, M.; Parini, P.

10.1101/2024.07.16.603677 — biochemistry — Posted on 2024-07-16

2603 Functionally constrained human proteins are less prone to disruption of stability caused by single amino acid substitutions

Andrews, D.; Lehmann, N.; May, M.; Goodall, L.; Cho, E.; Chuah, A.

10.1101/2024.07.14.603410 — genomics — Posted on 2024-07-16

2604 Cryo-EM Structures of Saccharolobus solfataricus Initiation Complexes with Leaderless mRNAs Highlight Archaeal Features and Eukaryotic Proximity

BOURGEOIS, G.; Coureux, P.-D.; lazennec-Schurdevin, c.; MADRU, C.; Gaillard, T.; Duchateau, M.; Chamot-Rooke, J.; Bourcier, S.; Mechulam, Y.; Schmitt, E.

10.1101/2024.07.16.603699 — molecular biology — Posted on 2024-07-16

2605 Spatial evidence of cryptic methane cycling and methylotrophic metabolisms along a land-ocean transect in a California coastal wetland

Krause, S. J. E.; Wipfler, R. L.; Liu, J.; Yousavich, D. J.; Robinson, D.; Hoyt, D. W.; Orphan, V. J.; Treude, T.

10.1101/2024.07.16.603764 — microbiology — Posted on 2024-07-16

2606 Identification and partial reconstitution of the biosynthetic pathway of bioactive meroterpenoids from Hericium erinaceus (Lion's Mane mushroom).

Iacovelli, R.; Poon, F.; Haslinger, K.

10.1101/2024.07.16.603773 — microbiology — Posted on 2024-07-16

2607 HerpesFolds: A proteome-wide structural systems approach reveals insights into protein families and activities of all nine human herpesviruses

Soh, T. K.; Ognibene, S.; Sanders, S.; Kaufer, B. B.; Bosse, J. B.

10.1101/2024.07.16.603793 — microbiology — Posted on 2024-07-16

2608 Elucidating the Diversity and Potential Function of Ribosomally Synthesized and Post-translationally Modified Peptides in the Human Microbiome

ZHANG, J.; ZHANG, D.; ZHANG, J.; GAO, Y.; SHI, Y.; CAI, P.; ZHONG, Z.; HE, B.; LI, X.; LI, Y.

10.1101/2024.07.16.603675 — microbiology — Posted on 2024-07-16

2609 Identification of V. parvula and S. gordonii adhesins mediating co-aggregation and its impact on physiology and mixed biofilm structure

DORISON, L.; BECHON, N.; MARTIN-GALLAUSIAUX, C.; CHAMORRO RODRIGUEZ, S. V.; VITRENKO, Y.; OUAZAHROU, R.; VILLA, R.; DESCHAMPS, J.; BRIANDET, R.; GRIBALDO, S.; GHIGO, J.-M.; BELOIN, C.

10.1101/2024.07.16.603716 — microbiology — Posted on 2024-07-16

2610 Global Prevalence of Cryptosporidium Infections in Cattle and C. parvum genotype distribution: A Meta-Analysis

Buchanan, R.; Matechou, E.; Katzer, F. D.; Tsaousis, A. D.; Farre, M.

10.1101/2024.07.16.603704 — microbiology — Posted on 2024-07-16

2611 Functional genomics of chitin degradation by Vibrio parahaemolyticus reveals finely integrated metabolic contributions to support environmental fitness

Getz, L.; Robinson, O.; Thomas, N. A.

10.1101/2024.07.16.603657 — microbiology — Posted on 2024-07-16

2612 Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines

Fantin, R.; Clark, J.; Cohn, H.; Jaiswal, D.; Bozarth, B.; Civljak, A.; Rao, V.; Lobo, I.; Nardulli, J.; Srivastava, K.; Yong, J.; Andreata-Santos, R.; Bushfield, K.; Lee, E.; Singh, G.; Study group, P.; Kleinstein, S.; Krammer, F.; Simon, V.; Bajic, G.; Coelho, C.

10.1101/2024.07.15.602781 — immunology — Posted on 2024-07-16

2613 Functional implications of the interaction of the SARS-CoV-2 Nucleocapsid protein with factors involved in nonsense-mediated mRNA decay

Mallick, M.; Boehm, V.; Xue, G.; Blackstone, M.; Gehring, N. H.; Chakrabarti, S.

10.1101/2024.07.16.603698 — biochemistry — Posted on 2024-07-16

2614 The SARS-CoV-2 nucleocapsid protein inhibits the cellular Nonsense-Mediated mRNA Decay (NMD) pathway preventing the full enzymatic activation of UPF1.

Nuccetelli, V.; Mghezzi-Habellah, M.; Deymier, S.; Roisin, A.; Gerard-Baraggia, F.; Rocchi, C.; Coureux, P.-D.; Gouet, P.; Cimarelli, A.; Mocquet, V.; Fiorini, F.

10.1101/2024.07.16.603692 — biochemistry — Posted on 2024-07-16

2615 Caenorhabditis elegans SynMuv B gene activity is down-regulated during a viral infection to enhance RNA interference

Seetharaman, A.; Galagali, H.; Linarte, E.; Liu, M. H. X.; Cohen, J. D.; Chetal, K.; Sadreyev, R.; Tate, A. J.; Montgomery, T. A.; Ruvkun, G.

10.1101/2024.07.12.603258 — genetics — Posted on 2024-07-16

2616 Lineage-specific genomic imprinting in the ZNF791 locus

Ahn, J.; Hwang, I.-S.; Park, M.-R.; Rosa-Velazquez, M.; Cho, I.-C.; Relling, A. E.; Hwang, S.; Lee, K.

10.1101/2024.07.13.603355 — genetics — Posted on 2024-07-16

2617 Complex Reticulation in Backbone Subfamily Relationships in Leguminosae

Stai, J.; Cardinal-McTeague, W.; Bruneau, A.; Cannon, S. B.

10.1101/2024.07.12.603319 — evolutionary biology — Posted on 2024-07-16

2618 Redundancy protects processing speed in healthy individuals with accelerated brain aging

Stanford, W.; Mucha, P. J.; Dayan, E.

10.1101/2024.07.12.603314 — neuroscience — Posted on 2024-07-16

2619 High fat diet induces differential age- and gender-dependent changes in neuronal function linked to redox stress.

de Lange, M.; Yarosh, V.; Farel, K.; Oates, C.; Patil, R.; Hawthorn, I.; Jung, M.-M.; Wenje, S.; Steinert, J. R.

10.1101/2024.07.12.603123 — neuroscience — Posted on 2024-07-16

2620 ROLE OF FORELIMB MORPHOLOGY IN MUSCLE SENSORIMOTOR FUNCTIONS DURING LOCOMOTION IN THE CAT

Rahmati, S. M.; Klishko, A. N.; Martin, R. S.; Bunderson, N. E.; Meslie, J. A.; Nichols, T. R.; Rybak, I. A.; Frigon, A.; Burkholder, T. J.; Prilutsky, B. I.

10.1101/2024.07.11.603106 — neuroscience — Posted on 2024-07-16

2621 Extracellular Vesicles from hiPSC-derived NSCs Protect Human Neurons against Abeta-42 Oligomers Induced Neurodegeneration, Mitochondrial Dysfunction and Tau Phosphorylation

Rao, S.; Madhu, L. N.; Babu, R. S.; Nagarajan, A.; Upadhya, R.; Narvekar, E.; Shetty, A. K.

10.1101/2024.07.11.603159 — neuroscience — Posted on 2024-07-16

2622 The Calmodulin-like proteins, CML13 and CML14 Function as Myosin Light Chains for the Class XI Myosins in Arabidopsis

Symonds, K.; Duff, L.; Dwivedi, V.; Belausov, E.; Pal, L.; Tominaga, M.; Haraguchi, T.; Sadot, E.; Ito, K.; Snedden, W.

10.1101/2024.07.11.603113 — plant biology — Posted on 2024-07-16

2623 Mangrove endophytes enhance yield and convey flooding and salt tolerance to Nipponbare rice

Hirt, H.; Saad, M. M.; Alghamdi, A.; Rawat, A. R.; nagarajan, a. P.; parween, s.

10.1101/2024.07.12.603329 — plant biology — Posted on 2024-07-16

2624 Portal bile acids and microbiota along the murine intestinal tract exhibit sex differences in physiology

Reichardt, F.; Lucas, L.; Okyere, L.; Choi, J.; Amador-Nogez, D.; Gaulke, C.; Anakk, S.

10.1101/2024.07.12.603325 — physiology — Posted on 2024-07-16

2625 The role of β-Nicotyrine in E-Cigarette abuse liability I: Drug Discrimination

Smethells, J.; Wilde, S.; Muelken, P.; LeSage, M.; Harris, A.

10.1101/2024.07.12.603310 — pharmacology and toxicology — Posted on 2024-07-16

2626 Effects of N361 Glycosylation on Epidermal Growth Factor Receptor Biological Function

Lam, D.; Arroyo, B.; Liberchuk, A. N.; Wolfe, A. L.

10.1101/2024.07.12.603279 — cancer biology — Posted on 2024-07-16

2627 Cells in the Polyaneuploid Cancer Cell State are Pro-Metastatic

Mallin, M. M.; Rolle, L. T. A.; Schmidt, M. J.; Priyadarsini Nair, S.; Zurita, A. J.; Kuhn, P.; Hicks, J.; Pienta, K. J.; Amend, S. R.

10.1101/2024.07.12.603285 — cancer biology — Posted on 2024-07-16

2628 Denoising, Deblurring, and optical Deconvolution for cryo-ET and light microscopy with a physics-informed deep neural network DeBCR

Li, R.; Yushkevich, A.; Chu, X.; Kudryashev, M.; Yakimovich, A.

10.1101/2024.07.12.603278 — bioinformatics — Posted on 2024-07-16

2629 Localized in vivo gene editing of murine cancer-associated fibroblasts

Kuhn, N. F.; Zaleta-Linares, I.; Nyberg, W. A.; Eyquem, J.; Krummel, M. F.

10.1101/2024.07.11.603114 — bioengineering — Posted on 2024-07-16

2630 Highly quantitative measurement of differential protein-genome binding with PerCell chromatin sequencing

Tallan, A.; Kucinski, J.; Sunkel, B.; Taslim, C.; LaHaye, S.; Liu, Q.; Qi, J.; Wang, M.; Kendall, G. C.; Stanton, B. Z.

10.1101/2024.07.12.603283 — genomics — Posted on 2024-07-16

2631 Nanopore-based native RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between RNA regulatory features

Vu, L. P.; Kim, Y.; O'Neil, K.; Garant, J.-M.; Saville, L.; Haile, S.; Ghashghaei, M.; Park, Y.; Jones, S.

10.1101/2024.07.11.603105 — genomics — Posted on 2024-07-16

2632 Two liverworts from same habitats developed many similar but few distinct seasonal adaptive strategies: Insights from a transcriptomic approach

Basu, S.; Yadav, S.; Jha, V. K.; Biswas, S.; Srivastava, A.; Tripathi, K.; Mondal, R.; Chaurasia, N.; Singh, S. K.; Mishra, Y.

10.1101/2024.07.12.603233 — genomics — Posted on 2024-07-16

2633 MalKinID: A Likelihood-Based Model for Identifying Malaria Parasite Genealogical Relationships Using Identity-by-Descent

Wong, W.; Wang, L.; Schaffner, S.; Li, X.; Cheeseman, I. H.; Anderson, T. J.; Vaughan, A. M.; Ferdig, M. T.; Volkman, S. K.; Hartl, D. L.; Wirth, D.

10.1101/2024.07.12.603328 — genetics — Posted on 2024-07-16

2634 Elevational constraints on flight efficiency shape global gradients in avian wing morphology

Yang, J.; Yang, C.; Lin, H.-w.; Lees, A. C.; Tobias, J. A.

10.1101/2024.07.12.603304 — evolutionary biology — Posted on 2024-07-16

2635 Long-term population dynamics of an endangered butterfly are influenced by hurricane-mediated disturbance

Steele Cabrera, S.; Belitz, M.; Emmel, T.; Khazan, E.; Standridge, M.; Rossetti, K.; Daniels, J.

10.1101/2024.07.12.603220 — ecology — Posted on 2024-07-16

2636 Influence of predation mortality on past and future dynamics of Pacific Herring: implications for stock status and future biomass

Doherty, B.; Johnson, S. D. N.; Benson, A. J.; Cox, S. P.; Cleary, J. S.; Lane, J.

10.1101/2024.07.12.603178 — ecology — Posted on 2024-07-16

2637 Single-cell transcriptomics reveal differences between chorionic and basal plate cytotrophoblasts and trophoblast stem cells

Morey, R. E.; Soncin, F.; Kallol, S.; Sah, N.; Manalo, Z.; Bui, T.; Slamecka, J.; Cheung, V. C.; Pizzo, D.; Requena, D. F.; Chang, C.-W.; Farah, O.; Kittle, R.; Meads, M.; Horii, M.; Fisch, K.; Parast, M. M.

10.1101/2024.07.12.603155 — developmental biology — Posted on 2024-07-16

2638 Elp1 function in placode-derived neurons is critical for proper trigeminal ganglion development

Hines, M. A.; Taneyhill, L. A.

10.1101/2024.07.12.603323 — developmental biology — Posted on 2024-07-16

2639 An enterococcal phage protein broadly inhibits type IV restriction enzymes involved in antiphage defense

Bullen, N. P.; Johnson, C. N.; Andersen, S. E.; Arya, G.; Marotta, S. R.; Lee, Y.-J.; Weigele, P.; Whitney, J. C.; Duerkop, B. A.

10.1101/2023.11.16.567456 — microbiology — Posted on 2024-07-16

2640 IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient mice

Hao, K.; Gao, K. M.; Strauss, M.; Subramanian, S.; Marshak-Rothstein, A.

10.1101/2024.07.10.602775 — immunology — Posted on 2024-07-16

2641 A SMARTR workflow for multi-ensemble atlas mapping and brain-wide network analysis

Jin, M.; Ogundare, S.; Lanio, M.; Sorid, S.; Whye, A. R.; Leal Santos, S.; Franceschini, A.; Denny, C. A.

10.1101/2024.07.12.603299 — neuroscience — Posted on 2024-07-16

2642 How the window of visibility varies around polar angle

Kwak, Y.; Lu, Z.-L.; Carrasco, M.

10.1101/2024.07.12.603257 — neuroscience — Posted on 2024-07-16

2643 Fc-engineered large molecules targeting blood-brain barrier transferrin receptor and CD98hc have distinct central nervous system and peripheral biodistribution compared to standard antibodies

Khoury, N.; Pizzo, M. E.; Discenza, C. B.; Joy, D.; Tatarakis, D.; Todorov, M. I.; Negwer, M.; Ha, C.; De Melo, G. L.; Sarrafha, L.; Simon, M. J.; Chan, D.; Chau, R.; Chew, K.; Chow, J.; Clemens, A.; Robles-Colmenares, Y.; Dugas, J. C.; Duque, J.; Kaltenecker, D.; Kane, H.; Leung, A.; Lozano, E.; Moshkforoush, A.; Roche, E.; Sandmann, T.; Tong, M.; Xa, K.; Zhou, Y.; Lewcock, J. W.; Erturk, A.; Thorne, R. G.; Calvert, M. E. K.; Zuchero, Y. J. Y.

10.1101/2024.07.11.602993 — neuroscience — Posted on 2024-07-16

2644 Muller glia cell cycle re-activation by simultaneous cyclin D1 overexpression and p27kip1 knockdown promotes retinal regeneration in mice

Wu, Z.; Liao, B.; Ying, J.; Keung, J.; Zheng, Z.; Ahola, V.; Xiong, W.

10.1101/2024.07.12.603194 — neuroscience — Posted on 2024-07-16

2645 Cerebellar output shapes cortical preparatory activity during motor adaptation

Israely, S.; Ninou, H.; Rajchert, O.; Elmaleh, L.; Harel, R.; Mawase, F.; Kadmon, J.; Prut, Y.

10.1101/2024.07.12.603354 — neuroscience — Posted on 2024-07-16

2646 Appropriate data segmentation improves speech encoding models

Bialas, O.; Lalor, E. C.

10.1101/2024.07.13.603356 — neuroscience — Posted on 2024-07-16

2647 Residual Microglia Following Short-term PLX5622 Treatment in 5xFAD Mice Exhibit Diminished NLRP3 Inflammasome and mTOR Signaling, and Enhanced Autophagy

Kodali, M.; Madhu, L. N.; Somayaji, Y.; Attaluri, S.; Huard, C.; Panda, P. K.; Shankar, G.; Rao, S.; Shuai, B.; Gonzalez, J. J.; Oake, C.; Hering, C.; Babu, R. S.; Kotian, S.; Shetty, A. K.

10.1101/2024.07.11.603157 — neuroscience — Posted on 2024-07-16

2648 Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron

Aguilar, G. R.; Vidal, B.; Ji, H.; Evenblij, J.; Ji, H.; Valperga, G.; Liao, C.-P.; Fang-Yen, C.; Hobert, O.

10.1101/2024.07.12.603289 — neuroscience — Posted on 2024-07-16

2649 Female sex hormones exacerbate retinal neurodegeneration

Rowe, A. A.; Reyes, S.; Velasquez, M. J.; Yee, T.; Nettesheim, E. R.; McDonald, J. G.; Wert, K. J.

10.1101/2024.07.11.603104 — neuroscience — Posted on 2024-07-16

2650 Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases

Jiang, J.; Gwee, J.; Fang, J.; Leichter, S. M.; Sanders, D.; Ji, X.; Song, J.; Zhong, X.

10.1101/2024.07.11.603080 — plant biology — Posted on 2024-07-16

2651 A moderate water deficit induces profound changes in the proteome of developing maize ovaries

Balliau, T.; Ashenafi, M.; Blein-Nicolas, M.; Turc, O.; Zivy, M.; MARCHADIER, E.

10.1101/2024.07.12.603247 — plant biology — Posted on 2024-07-16

2652 ExPOSE: A comprehensive toolkit to perform expansion microscopy in plant protoplast systems

Cox, K. L.; Pardi, S. A.; O'Connor, L.; Klebanovych, A.; Huss, D. J.; Nusinow, D. A.; Meyers, B. C.; Czymmek, K. J.

10.1101/2024.07.12.603300 — plant biology — Posted on 2024-07-16

2653 Direct non-transcriptional link between brassinosteroid perception and cortical microtubule reorientation drives hypocotyl growth

Delesalle, C.; Montiel Jorda, A.; Neveu, J.; Fujita, S.; Vert, G.

10.1101/2024.07.12.603229 — plant biology — Posted on 2024-07-16

2654 FLASH Bragg-peak irradiation with a therapeutic carbon ion beam: first in vivo results

Tinganelli, W.; Sokol, O.; Puspitasari, A.; Helm, A.; Simoniello, P.; Schuy, C.; Lerchl, S.; Eckert, D.; Oppermann, J.; Rehm, A.; Janssen, S.; Engel, D.; Moeller, R.; Romano, R.; Fournier, C.; Durante, M.; Weber, U.

10.1101/2024.07.12.603197 — cancer biology — Posted on 2024-07-16

2655 Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response in mice and humans

Skelly, D. A.; Graham, J. P.; Cheng, M.; Furuta, M.; Walter, A.; Stoklasek, T. A.; Yang, H.; Stearns, T. M.; Poirion, O.; Zhang, J.-G.; Grassmann, J. D. S.; Luo, D.; Flynn, W. F.; Courtois, E. T.; Chang, C.-H.; Serreze, D. V.; Menghi, F.; Reinholdt, L. G.; Liu, E. T.

10.1101/2024.07.11.603136 — cancer biology — Posted on 2024-07-16

2656 Drug-repurposing screen identifies thiostrepton as a novel regulator of the tumor suppressor DAB2IP

De Florian Fania, R.; Maiocchi, S.; Klima, R.; Pellegrini, V.; Ghetti, S.; Selvestrel, D.; Fava, L. L.; Braga, L.; Collavin, L.

10.1101/2024.07.12.603185 — cancer biology — Posted on 2024-07-16

2657 Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo

Kucinski, J.; Tallan, A.; Taslim, C.; Wang, M.; Cannon, M. V.; Silvius, K. M.; Stanton, B. Z.; Kendall, G. C.

10.1101/2024.07.12.603270 — cancer biology — Posted on 2024-07-16

2658 Context-dependent roles for autophagy in myeloid cells in tumor progression

Choi, J.; Park, G.; Lee, S. S.-Y.; Dominici, E.; Becker, L.; Macleod, K. F.; KRON, S. J.; Hwang, S.

10.1101/2024.07.12.603292 — cancer biology — Posted on 2024-07-16

2659 Mathematical Modelling of Reoviruses in Cancer Cell Cultures

Baabdulla, A. A.; Cristi, F.; Shmulevitz, M.; Hillen, T.

10.1101/2024.07.12.603333 — cancer biology — Posted on 2024-07-16

2660 A new alignment-free method: Subsequence Correlation Coefficient Vector(SCCFV) for influenza A comparison using virus genomes

He, L.; Yu, Z.; Wu, X.; Zhu, Y.

10.1101/2024.07.12.603253 — bioinformatics — Posted on 2024-07-16

2661 Composite Hedges Nanopores: A High INDEL-Correcting Codec System for Rapid and Portable DNA Data Readout

Zhao, X.; Li, J.; Fan, Q.; Dai, J.; Long, Y.; Liu, R.; Zhai, J.; Pan, Q.; Li, Y.

10.1101/2024.07.12.603190 — bioinformatics — Posted on 2024-07-16

2662 The discovery of phages in the Substantia Nigra and its implication for Parkinson's Disease

Zhao, Y.; Xiong, C.; Wang, B.; Li, D.; Liu, J.; Wei, S.; Hou, Y.; Zhou, Y.; Zheng, R.

10.1101/2024.07.13.603353 — bioinformatics — Posted on 2024-07-16

2663 The state-of-the-art machine learning model for Plasma Protein Binding Prediction: computational modeling with OCHEM and experimental validation

Han, Z.; Xia, Z.; Xia, J.; Tetko, I. V.; Wu, S.

10.1101/2024.07.12.603170 — bioinformatics — Posted on 2024-07-16

2664 CircCNNs, a convolutional neural network framework to better understand the biogenesis of exonic circRNAs

Wang, C.; Liang, C.

10.1101/2024.07.12.603307 — bioinformatics — Posted on 2024-07-16

2665 ProtParts, an automated web server for clustering and partitioning protein datasets

Li, Y.; Barra, C.

10.1101/2024.07.12.603234 — bioinformatics — Posted on 2024-07-16

2666 CompareM2 is a genomes-to-report pipeline for comparing microbial genomes

Kobel, C. M.; Aho, V. T. E.; Oeyaas, O.; Noerskov-Lauritsen, N.; Woodcroft, B. J.; Pope, P. B.

10.1101/2024.07.12.603264 — bioinformatics — Posted on 2024-07-16

2667 A Novel Registration Framework for Aligning Longitudinal Infant Brain Tensor Images

Duan, K.; Li, L.; Calhoun, V.; Shultz, S.

10.1101/2024.07.12.603305 — bioengineering — Posted on 2024-07-16

2668 CELLNET technology: Spatially organized, functional 3D networks at single cell resolution

Soman, P.; Poudel, A.; Kunwar, P.; Aryal, U.; Merife, A.-B.

10.1101/2024.07.12.603216 — bioengineering — Posted on 2024-07-16

2669 16,000 combinatorial DNA rings">Assembling a true "Olympic Gel" from >16,000 combinatorial DNA rings

Speed, S.; Atabay, A.; Peng, Y.-H.; Gupta, K.; Müller, T.; Fischer, C.; Sommer, J.-U.; Lang, M.; Krieg, E.

10.1101/2024.07.12.603212 — bioengineering — Posted on 2024-07-16

2670 The progression of infiltrating neurovascular features and chemokine production of the caudal intervertebral disc following injury

Walk, R.; Broz, K.; Jing, L.; Potter, R.; Beeve, A.; Scheller, E.; Gupta, M.; Setton, L.; Tang, S. Y.

10.1101/2024.07.12.603182 — bioengineering — Posted on 2024-07-16

2671 Specialization into Host Sea Anemones Impacted Clownfish Demographic Responses to Pleistocene Sea Level Changes

Garcia Jimenez, A.; Gaboriau, T.; Fitzgerald, L. M.; Heim, S.; Marcionetti, A.; Schmid, S.; Bertrand, J.; Litsios, G.; Frederich, B.; Cortesi, F.; Yemin, T.; Salamin, N.

10.1101/2024.07.12.603135 — genomics — Posted on 2024-07-16

2672 Distinct structural and functional heterochromatin partitioning of lamin B1 and B2 revealed using genome-wide Nicking Enzyme Epitope targeted DNA sequencing.

Sen, S.; Esteve, P. O.; Karthikeyan, R.; Beaulieu, J.; Chin, H. G.; Feehary, G.; Vishnu, U. S.; Xu, S. y.; Samuelson, J.; Pradhan, S.

10.1101/2024.07.11.603107 — genomics — Posted on 2024-07-16

2673 Somy evolution in the honey bee infecting trypanosomatid parasite, Lotmaria passim

Markowitz, L. M.; Nearman, A.; Zhao, Z.; Boncristiani, D.; Butenko, A.; de Pablos, L. M.; Marin, A.; Xu, G.; Machado, C. A.; Schwarz, R. S.; Palmer-Young, E. C.; Evans, J. D.

10.1101/2024.07.12.603340 — genomics — Posted on 2024-07-16

2674 A wavelet-based approach generates quantitative, scale-free and hierarchical descriptions of 3D genome structures and new biological insights

Pellow, R.; Comeron, J. M.

10.1101/2024.07.12.603291 — genomics — Posted on 2024-07-16

2675 Waves of transcription drive erythroid differentiation and launch the NRF2-activated antioxidant program

Karppi, I.; Pessa, J. C.; Rabenius, A.; Himanen, S.; Prajapati, B.; Barkman Jonsson, E.; Vartiainen, M. K.; Sistonen, L.; Vihervaara, A.

10.1101/2024.07.12.603281 — genomics — Posted on 2024-07-16

2676 Emergence of sympatric host-specific lineages of the fungal plant pathogen Zymoseptoria passerinii in natural ecosystems

Rojas-Barrera, I. C.; Flores-Nunez, V. M.; Haueisen, J.; Alizadeh, A.; Salimi, F.; Stukenbrock, E. H.

10.1101/2024.07.12.603051 — evolutionary biology — Posted on 2024-07-16

2677 Consistent and scalable monitoring of birds and habitats along a coffee production intensity gradient

Somveille, M.; Grainger-Hull, J.; Ferguson, N.; Sethi, S. S.; Gonzalez Garcia, F.; Chassagnon, V.; Oktem, C.; Disney, M.; Lopez Bautista, G.; Vandermeer, J.; Perfecto, I.

10.1101/2024.07.12.603271 — ecology — Posted on 2024-07-16

2678 Scales of marine endemism in oceanic islands and the Provincial-Island endemism

Pinheiro, H. T.; Rocha, L. A.; Quimbayo, J. P.

10.1101/2024.07.12.603346 — ecology — Posted on 2024-07-16

2679 Modeling plant-microbe interactions with species distribution models

Wang, Z.; Piche-Choquette, S.; Lauzon, J.; Ishak, S.; Kembel, S. W.

10.1101/2024.07.12.603317 — ecology — Posted on 2024-07-16

2680 Unbounding fish: Assessing vulnerability to overexploitation for transboundary fish populations

Gangal, M.; Arthur, R.; Suri, V.; Pandit, A.; Tyagi, A.; Prakash, P.; Sule, M.; Majgaonkar, I.; Krishnaswamy, J.; Ramakrishnan, U.

10.1101/2024.07.12.603026 — ecology — Posted on 2024-07-16

2681 Nitrogen sharing strategies in six clonal species

Duchoslavova, J.

10.1101/2024.07.12.603230 — ecology — Posted on 2024-07-16

2682 The Once and Future Fish: 1300 years of Atlantic herring population structure and demography revealed through ancient DNA and mixed-stock analysis

Atmore, L. M.; van der Jagt, I.; Boilard, A.; Haeberle, S.; Blevis, R.; Dierickx, K.; Quinlan, L. M.; Orton, D. C.; Hufthammer, A. K.; Barrett, J. H.; Star, B.

10.1101/2024.07.11.603078 — ecology — Posted on 2024-07-16

2683 Pulsatile dynamics propagate crystalline order in the developing Drosophila eye

Couturier, L.; Luna-Escalante, J.; Mazouni, K.; Mestdagh, C.; Phan, M.-S.; Tinevez, J.-Y.; Schweisguth, F.; Corson, F.

10.1101/2024.07.11.603179 — developmental biology — Posted on 2024-07-16

2684 Dysregulation of gene expression during gastrulation results in impaired primitive erythropoiesis and vascular development in Trim71-KO embryos

Beckroege, T.; Jux, B.; Seifert, H.; Theobald, H.; De Domenico, E.; Paulusch, S.; Beyer, M.; Schlitzer, A.; Mass, E.; Kolanus, W.

10.1101/2024.07.12.603214 — developmental biology — Posted on 2024-07-16

2685 A Single Trophoblast Layer Acts as the Gatekeeper at the Endothelial-Hematopoietic Crossroad in the Placenta

Home, P.; Ghosh, A.; Kumar, R. P.; Ray, S.; Gunewardena, S.; Kumar, R.; Dasgupta, P.; Roy, N.; Saha, A.; Ouseph, M. M.; Leone, G. W.; Paul, S.

10.1101/2024.07.12.603303 — developmental biology — Posted on 2024-07-16

2686 The Rbfox1/LASR complex controls alternative pre-mRNA splicing by recognition of multi-part RNA regulatory modules

Peyda, P.; Lin, C.-H.; Onwuzurike, K.; Black, D. L.

10.1101/2024.07.12.603345 — molecular biology — Posted on 2024-07-16

2687 Coordinated network of T cells and antigen presenting cells regulate tolerance to food

Rudnitsky, A.; Oh, H.; Talmor, J.; Kedmi, R.

10.1101/2024.07.11.603064 — immunology — Posted on 2024-07-16

2688 Resident memory T cells in dirty mice suppress innate cell activation and infiltration into the skin following stimulation with alarmins.

Story, M. E.; Ferris, L. K.; Mathers, A. R.

10.1101/2024.07.11.602963 — immunology — Posted on 2024-07-16

2689 T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

Zhao, Y.; Zhu, H.; Li, J.; Sun, L.

10.1101/2024.07.11.603062 — immunology — Posted on 2024-07-16

2690 Card9 and MyD88 differentially regulate Th17 immunity to the commensal yeast Malassezia in the murine skin

Tuor, M.; Stappers, M. H. T.; Ruchti, F.; Desgardin, A.; Sparber, F.; Orr, S. J.; Gow, N. A. R.; LeibundGut-Landmann, S.

10.1101/2024.07.12.603211 — immunology — Posted on 2024-07-16

2691 Langerhans cells regulate immunity in adulthood by regulating postnatal dermal lymphatic development

Sim, J. H.; Bell, R.; Feng, Z.; Chyou, S.; Shipman, W.; Kataru, R.; Ivashkiv, L.; Mehrara, B.; Lu, T.

10.1101/2024.07.12.603312 — immunology — Posted on 2024-07-16

2692 YTHDF2 upregulation and relocation dictate CD8 T cell polyfunctionality in tumor immunity

Zhang, H.; Luo, X.; Yang, W.; Wu, Z.; Zhao, Z.; Pei, X.; Zhang, X.; Chen, C.; Lei, J. H.; Shi, Q.; Zhao, Q.; Chen, Y.; Wu, W.; Zeng, Z.; Ju, H.-Q.; Qiu, M.; Liu, J.; Shen, B.; Chen, M.; Chen, J.; Deng, C.-X.; Xu, R.-H.; Hou, J.

10.1101/2024.07.11.603088 — immunology — Posted on 2024-07-16

2693 Macrophage-derived CCL24 promotes fibrosis and worsens cardiac dysfunction during heart failure

Parthiban, P.; Barrow, F.; Nguyen, H.; Neto, F.; Florczak, K.; Wang, H.; Yucel, D.; Liu, H.; Draxler, M.; Ciske, E.; Fredrickson, G.; Herman, A.; Rothenberg, M.; Dudley, S.; van Berlo, J. H.; Revelo, X.

10.1101/2024.07.12.603277 — immunology — Posted on 2024-07-16

2694 Parallel HIV-1 evolutionary dynamics in humans and rhesus macaques who develop broadly neutralizing antibodies

Shimagaki, K. S.; Lynch, R. M.; Barton, J. P.

10.1101/2024.07.12.603090 — immunology — Posted on 2024-07-16

2695 Spatially organized striatum-wide acetylcholine dynamics for the learning and extinction of Pavlovian cues and actions

Bouabid, S.; Zhang, L.; Vu, M.-A. T.; Tang, K.; Graham, B. M.; Noggle, C. A.; Howe, M. W.

10.1101/2024.07.10.602947 — neuroscience — Posted on 2024-07-16

2696 Neural specialisation for concrete and abstract concepts revealed through meta-analysis

Hoffman, P.; Bair, M.

10.1101/2024.07.11.603079 — neuroscience — Posted on 2024-07-16

2697 Tempo-dependent selective enhancement of neural responses at the beat frequency can be explained by both an oscillator and an evoked model

Damsma, A.; de Roo, M.; Doelling, K.; Bazin, P.-L.; Bouwer, F. L.

10.1101/2024.07.11.603023 — neuroscience — Posted on 2024-07-16

2698 Chaotic synchronization in adaptive networks of pulse-coupled oscillators

Mato, G.; Politi, A.; Torcini, A.

10.1101/2024.07.11.603061 — neuroscience — Posted on 2024-07-16

2699 Direct piriform-to-auditory cortical projections shape auditory-olfactory integration

Vogler, N. W.; Chen, R.; Virkler, A.; Tu, V. Y.; Gottfried, J. A.; Geffen, M. N.

10.1101/2024.07.11.602976 — neuroscience — Posted on 2024-07-16

2700 Mild neonatal hypoxia disrupts adult hippocampal learning and memory and is associated with CK2-mediated dysregulation of synaptic calcium-activated potassium channel KCNN2

Riddle, A.; Srivastava, T.; Wang, K.; Tellez, E.; O'neill, H.; Gong, X.; O'Neil, A.; Bell, J. A.; Raber, J.; Lattal, M.; Maylie, J.; Back, S. A.

10.1101/2024.07.10.602558 — neuroscience — Posted on 2024-07-16

2701 On the Geometry of Somatosensory Representations in the Cortex

Saadon-Grosman, N.; Asher, T.; Loewenstein, Y.

10.1101/2024.07.11.603013 — neuroscience — Posted on 2024-07-16

2702 Rapid eye and hand responses in an interception task are differentially modulated by context-dependent predictability

Balalaie, P.; Park, K.; Fooken, J.

10.1101/2024.07.11.603058 — neuroscience — Posted on 2024-07-16

2703 Hearing and cognitive decline in aging differentially impact neural tracking of context-supported versus random speech across linguistic timescales

Bolt, E.; Kliestenec, K.; Giroud, N.

10.1101/2024.07.16.603693 — neuroscience — Posted on 2024-07-16

2704 Structural comparisons of human and mouse fungiform taste buds

High, B.; Finger, T. E.

10.1101/2024.07.10.602971 — neuroscience — Posted on 2024-07-16

2705 The Neural efficiency score: Validation and application

Wenger, M. J.; Townsend, J. T.; Newbolds, S. F.

10.1101/2024.07.11.603127 — neuroscience — Posted on 2024-07-16

2706 The flow state is not accompanied by frontal-midline theta activity: An EEG investigation of more than 700 video gameplay sessions

Sugino, H.; Ideriha, T.; Yamazaki, R.; Ushiyama, J.

10.1101/2024.07.11.603158 — neuroscience — Posted on 2024-07-16

2707 7 Tesla MRS estimates of GABA concentration relate to physiological measures of tonic inhibition in the human motor cortex

Paparella, I.; Cardone, P.; Zanichelli, B.; Lamalle, L.; Collette, F.; Sherif, S.; Zubkov, M.; Clarke, W. T.; Stagg, C. J.; Maquet, P.; Vandewalle, G.

10.1101/2024.07.12.603209 — neuroscience — Posted on 2024-07-16

2708 Persistent activity during working memory maintenance predicts long-term memory formation in the human hippocampus

Daume, J.; Kaminski, J.; Salimpour, Y.; Anderson, W. S.; Valiante, T. A.; Mamelak, A. N.; Rutishauser, U.

10.1101/2024.07.15.603630 — neuroscience — Posted on 2024-07-16

2709 EEG microstate transition cost correlates with task demands

Barzon, G.; Ambrosini, E.; Vallesi, A.; Suweis, S.

10.1101/2023.12.07.570625 — neuroscience — Posted on 2024-07-16

2710 Big Data in Myoelectric Control: LargeMulti-User Models Enable Robust Zero-ShotEMG-based Discrete Gesture Recognition

Eddy, E.; Campbell, E.; Bateman, S.; Scheme, E.

10.1101/2024.07.11.603119 — neuroscience — Posted on 2024-07-16

2711 Tracking changes in functionality and morphology of repopulated microglia in young and old mice

Kaminska, B.; Luczak-Sobotkowska, Z.; Rosa, P.; Banqueri-Lopez, M.; Ochocka, N.; Kiryk, A.; Lenkiewicz, A. M.; Fuhrmann, M.; Jankowski, A.

10.1101/2024.07.12.603244 — neuroscience — Posted on 2024-07-16

2712 REM sleep quality is associated with balanced tonic activity of the locus coeruleus during wakefulness

Mortazavi, N.; Talwar, P.; Koshmanova, E.; Sharifpour, R.; Beckers, E.; Berger, A.; Campbell, I.; Paparella, I.; Balda, F.; Dardour Hamzaoui, I.; Berthomier, C.; Bastin, C.; Phillips, C.; Maquet, P.; Collette, F.; Zubkov, M.; Lamalle, L.; Vandewalle, G.

10.1101/2024.07.12.603275 — neuroscience — Posted on 2024-07-16

2713 Cell-type specific binocular interactions in mouse visual thalamus

Masterson, S. P.; Govindaiah, G. E.; Guido, W.; Bickford, M. E.

10.1101/2024.07.12.603141 — neuroscience — Posted on 2024-07-16

2714 Local keratinocyte-nociceptor interactions enhance obesity-mediated small fiber neuropathy via NGF-TrkA-PI3K signaling axis

Koui, Y.; Song, S.; Dong, X.; Mukouyama, Y.-S.

10.1101/2024.07.12.603316 — neuroscience — Posted on 2024-07-16

2715 Generation of human appetite-regulating neurons and tanycytes from stem cells

Abay-Norgaard, Z.; Mueller, A. K.; Hanninen, E.; Rausch, D.; Piilgaard, L.; Christensen, J. B.; Peeters, S.; Schorling, A. L.; Salvador, A.; Nikulina, V.; Li, Y. K.; Kajtez, J.; Pers, T. H.; Kirkeby, A.

10.1101/2024.07.11.603039 — neuroscience — Posted on 2024-07-16

2716 Visual system structural and functional connections during face viewing in body dysmorphic disorder

Wong, W.-W.; Peel, H.; Cabeen, R. P.; Diaz-Fong, J. P.; Feusner, J. D.

10.1101/2024.07.12.603273 — neuroscience — Posted on 2024-07-16

2717 Spatial Transcriptomics and Single-Nucleus Multi-omics Analysis Revealing the Impact of High Maternal Folic Acid Supplementation on Offspring Brain Development

Xie, H.; Xu, X.; Lin, Y.; Yin, L.; Serpa, P. d. S.; Conacher, B.; Pacholac, C.; Carvallo, F.; Hrubec, T.; Farris, S.; Zimmerman, K.; Wang, X.

10.1101/2024.07.12.603269 — neuroscience — Posted on 2024-07-16

2718 Systematic evaluation of blastoid models of early human development

Kim, H. J.; Salehin, N.; Huang, H.; Zhang, X.; Jothi, R.; Yang, P.

10.1101/2024.07.11.603073 — systems biology — Posted on 2024-07-16

2719 Cell-TRACTR: A transformer-based model for end-to-end segmentation and tracking of cells

O'Connor, O. M.; Dunlop, M. J.

10.1101/2024.07.11.603075 — systems biology — Posted on 2024-07-16

2720 Climate adaptation in P. trichocarpa: key adaptive loci identified for stomata and leaf traits

Klein, M. C.; Meng, Z.; Bailey-Bale, J.; Milner, S.; Shi, P.; Muchero, W.; Chen, J.-G.; Tschaplinski, T. J.; Jacobson, D.; Lagergren, J.; Lane, M.; O Brien, C.; Chhetri, H.; Shu, M.; Freer-Smith, P.; Buckley, T. N.; Magney, T.; Monroe, J. G.; Tuskan, G. A.; Taylor, G.

10.1101/2024.07.11.603099 — plant biology — Posted on 2024-07-16

2721 Species wide inventory of Arabidopsis thaliana organellar variation reveals ample phenotypic variation for photosynthetic performance

Theeuwen, T. P. J. M.; Wijfjes, R. Y.; Dorussen, D.; Lawson, A. W.; Lind, J.; Jin, K.; Boekeloo, J.; Tijink, D.; Hall, D.; Hanhart, C.; Becker, F. F. M.; van Eeuwijk, F. A.; Kramer, D. M.; Wijnker, E.; Harbinson, J.; Koornneef, M.; Aarts, M. G. M.

10.1101/2024.07.12.603232 — plant biology — Posted on 2024-07-16

2722 DGTS overproduced in seed plants is excluded from plastid membranes and promotes endomembrane expansion

Salomon, S.; Schilling, M.; Albrieux, C.; Si Larbi, G.; Jouneau, P.-H.; Roy, S.; Falconet, D.; Michaud, M.; Jouhet, J.

10.1101/2024.07.11.603045 — plant biology — Posted on 2024-07-16

2723 Effects of leg immobilization and recovery resistance training on skeletal muscle-molecular markers in previously resistance trained versus untrained adults

Michel, J. M.; Godwin, J. S.; Plotkin, D. L.; McIntosh, M. C.; Mattingly, M. L.; Agostinelli, P. J.; Mueller, B. J.; Anglin, D. A.; Berry, A. C.; Vega, M. M.; Pipkin, A. A.; Stock, M. S.; Graham, Z. A.; Baweja, H. S.; Mobley, C. B.; Bamman, M. M.; Roberts, M. D.

10.1101/2024.07.12.603321 — physiology — Posted on 2024-07-16

2724 Filtering for highly variable genes and high quality spots improves phylogenetic analysis of cancer spatial transcriptomics Visium data

Gavryushkina, A.; Pinkney, H. R.; Diermeier, S.; Gavryushkin, A.

10.1101/2024.07.11.603166 — cancer biology — Posted on 2024-07-16

2725 Importance of transcript variants in transcriptome analyses

Vo, K.; Mohamadi, R.; Sharma, Y.; Mohamadi, A.; Fields, P. E.; Rumi, M. A. K.

10.1101/2024.07.11.603122 — bioinformatics — Posted on 2024-07-16

2726 CryoSamba: self-supervised deep volumetric denoising for cryo-electron tomography data

Costa-Filho, J. I.; Theveny, L.; de Sautu, M.; Kirchhausen, T.

10.1101/2024.07.11.603117 — bioinformatics — Posted on 2024-07-16

2727 AoUPRS: A Cost-Effective and Versatile PRS Calculator for the All of Us Program

Khattab, A.; Chen, S.-F.; Wineinger, N.; Torkamani, A.

10.1101/2024.07.11.603165 — bioinformatics — Posted on 2024-07-16

2728 Improving rigor and reproducibility in chromatin immunoprecipitation assay data analysis workflows with Rocketchip

Haghani, V.; Goyal, A.; Zhang, A.; Sharifi, O.; Mariano, N.; Yasui, D. H.; Korf, I. F.; LaSalle, J. M.

10.1101/2024.07.10.602975 — bioinformatics — Posted on 2024-07-16

2729 Peptipedia v2.0: A peptide sequence database and user-friendly web platform. A major update

Cabas, G. E.; Daza, A.; Soto, N.; Garrido, V.; Alvarez, D.; Navarrete, M.; Sarmiento-Varon, L.; Sepulveda, J.; D. Davari, M. E.; Cadet, F.; Olivera, A.; Uribe, R.; Medina-Ortiz, D.

10.1101/2024.07.11.603053 — bioinformatics — Posted on 2024-07-16

2730 GBMPurity: A Machine Learning Tool for Estimating Glioblastoma Tumour Purity from Bulk RNA-seq Data

Thomas, M. P. H.; Ajaib, S.; Tanner, G.; Bulpitt, A. J.; Stead, L. F.

10.1101/2024.07.11.602650 — bioinformatics — Posted on 2024-07-16

2731 Adapting Lateral Stepping Control to Walk on Winding Paths

Render, A. C.; Cusumano, J. P.; Dingwell, J. B.

10.1101/2024.07.11.603068 — bioengineering — Posted on 2024-07-16

2732 Comparison of Cd concentration in rice grain between OsNramp5 knock-out mutants and OsHAM3-overexpressing line

Gui, Y.; Teo, J.; Tian, D.; Mohan, R.; Yin, Z.

10.1101/2024.07.11.603016 — bioengineering — Posted on 2024-07-16

2733 BOOST: a robust ten-fold expansion method on hour-scale

Guo, J.; Yang, H.; Lu, C.; Cui, D.; Zhao, M.; Li, C.; Chen, W.; Yang, Q.; Li, Z.; Chen, M.; Zhao, S.; Zhou, J.; He, J.; Jiang, H.

10.1101/2024.07.11.603043 — bioengineering — Posted on 2024-07-16

2734 Mandrel Diameter is a Dominating Parameter for Fiber Alignment Control in Rotating Mandrel Electrospinning Systems

Meinhold, K. L.; Tankersley, T.; Darlington, R.; Robinson, J. L.

10.1101/2024.07.11.603153 — bioengineering — Posted on 2024-07-16

2735 Toward industrial C8 production: Oxygen intrusion drives renewable n caprylate production from ethanol and acetate via intermediate metabolite production

Gemeinhardt, K.; Seung Jeon, B.; Nepomuscene Ntihuga, J.; Wang, H.; Schlaiss, C.; Niklas, T. N.; Bessarab, I.; Nalpas, N. C.; Zhou, N.; Usack, J. G.; Huson, D.; Williams, R.; Macek, B.; Aristilde, L.; Angenent, L. T.

10.1101/2024.07.12.603245 — bioengineering — Posted on 2024-07-16

2736 Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntingtons disease

CHAKRABORTY, A.; Sreenivasmurthy, S. G.; Miller, W.; Huai, W.; Biswas, T.; Mandal, S. M.; Bosca, L.; Krishnan, B.; Ghosh, G.; Hazra, T.

10.1101/2023.10.26.564220 — biochemistry — Posted on 2024-07-16

2737 Comparative evaluation of four exome enrichment solutions in 2024: Agilent, Roche, Vazyme and Nanodigmbio

Belova, V.; Vasiliadis, I.; Repinskaia, Z.; Samitova, A.; Shmitko, A.; Ponikarovskaya, N.; Suchalko, O.; Cheranev, V.; Shatalov, P.; Shegai, P.; Kaprin, A.; Rebrikov, D.; Korostin, D.

10.1101/2024.07.11.602872 — genomics — Posted on 2024-07-16

2738 Recursive RePair: Increasing the Scalability of RePair by Decreasing Memory Usage

Kim, J.; Varki, R.; Oliva, M.; Boucher, C.

10.1101/2024.07.11.603142 — genomics — Posted on 2024-07-16

2739 Diet-induced obesity mediated through Estrogen-Related Receptor α is independent of intestinal function

Vemuri, K.; Iqbal, J.; Kumar, S.; Logerfo, A.; Verzi, M. P.

10.1101/2024.07.10.602978 — genetics — Posted on 2024-07-16

2740 Estimation of spatial demographic maps from polymorphism data using a neural network

Smith, C. C. R.; Patterson, G. C.; Ralph, P. L.; Kern, A. D.

10.1101/2024.03.15.585300 — evolutionary biology — Posted on 2024-07-16

2741 Robust coexistence in ecological competitive communities

Lechon-Alonso, P.; Kundu, S.; Lemos-Costa, P.; Allesina, S.

10.1101/2024.07.10.602979 — ecology — Posted on 2024-07-16

2742 Early signs of plant community responses to climate warming along mountain roads in Switzerland

Iseli, E.; Diaz Zeugin, N.; Brioschi, C.; Alexander, J.; Lenoir, J.

10.1101/2024.07.12.603213 — ecology — Posted on 2024-07-16

2743 The longitudinal growth of the embryo of the kelp Saccharina depends on actin filaments that control the formation of an alginate corset in the cell wall

Boscq, S.; Theodorou, I.; Milstein, R.; Le Bail, A.; Chenivesse, S.; Billoud, B.; Charrier, B.

10.1101/2024.07.10.603006 — developmental biology — Posted on 2024-07-16

2744 CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling

Bowman, R. L.; Kim, J.; Eom, D. S.

10.1101/2024.02.27.582398 — developmental biology — Posted on 2024-07-16

2745 First-male sperm precedence in polyandrous Spodoptera frugiperda allows sterile males induce population suppression

Sun, H.; Bu, L.-A.; Zhang, X.-Y.; Zhang, Z.-R.; Zhu, L.-Y.; Su, S.; Guo, D.; Hu, G.; Gao, C.-F.; Palli, S. R.; Champer, J.; Wu, S.-F.

10.1101/2024.07.10.602994 — zoology — Posted on 2024-07-16

2746 Appearance of green tea compounds in plasma following green tea consumption is modulated by the gut microbiome in mice

Sterrett, J. D.; Quinn, K. D.; Doenges, K. A.; Nusbacher, N.; Levens, C. L.; Armstrong, M. L.; Reisdorph, R. M.; Smith, H.; Saba, L. M.; Kuhn, K. A.; Lozupone, C.; Reisdorph, N.

10.1101/2024.07.11.603097 — systems biology — Posted on 2024-07-16

2747 TOR Inhibition Enhances Autophagic Flux and Immune Response in Tomato Plants Against PSTVd Infection

Silva, S.; Prol, F. V.; Rodrigo, I.; Lison, P.; Belda Palazon, B.

10.1101/2024.07.11.603042 — plant biology — Posted on 2024-07-16

2748 Trichoderma afroharzianum induces rhizobia and flavonoid through systemic signaling to combat iron deficiency in garden pea

Thapa, A.; Hasan, M. R.; Kabir, A. H.

10.1101/2024.07.11.603139 — plant biology — Posted on 2024-07-16

2749 Validation of a Demography-Based Adaptive QTc Formula using Pediatric and Adult Datasets Acquired from Humans and Guinea Pigs

Haq, K.; McLean, K.; Anderson-Barker, G.; Berul, C.; Shattock, M.; Posnack, N.

10.1101/2024.07.10.602984 — physiology — Posted on 2024-07-16

2750 Closing the gap in the clinical adoption of computational pathology: a standardized, open-source framework to integrate deep-learning algorithms into the laboratory information system

Angeloni, M.; Rizzi, D.; Schoen, S.; Caputo, A.; Merolla, F.; Hartmann, A.; Ferrazzi, F.; Fraggetta, F.

10.1101/2024.07.11.603091 — pathology — Posted on 2024-07-16

2751 Platelet integrin αIIbβ3 plays a key role in venous thrombogenesis in a mouse model

Adair, B. D.; Field, C. O.; Alonso, J. L.; Xiong, J.-P.; Deng, S.-X.; Ahn, H. S.; Mashin, E.; Clish, C. B.; van Agthoven, J.; Yeager, M.; Guo, Y.; Tess, D. A.; Landry, D. W.; Poncz, M.; Arnaout, M. A.

10.1101/2024.07.11.602533 — pathology — Posted on 2024-07-16

2752 Effects of clinically relevant radionuclides on the activation of a type I interferon response by radiopharmaceuticals in syngeneic murine tumor models

Kerr, C. P.; Sheehan-Klenk, J.; Grudzinski, J. J.; Adam, D. P.; Nguyen, T. P. T.; de Aguiar Ferreira, C.; Bates, A. M.; Jin, W. J.; Kwon, O.; Olson, A. P.; Lin, W.; Hyun, M.; Jagodinsky, J. C.; Powers, M.; Sriramaneni, R. N.; Clark, P. A.; Shea, A. G.; Comas Rojas, H.; Choi, C.; Massey, C. F.; Zangl, L. M.; Pinchuk, A. N.; Aluicio-Sarduy, E.; Kim, K.; Engle, J. W.; Hernandez, R.; Bednarz, B. P.; Weichert, J. P.; Morris, Z. S.

10.1101/2024.07.10.602990 — cancer biology — Posted on 2024-07-16

2753 Obscured Complexity: How External Cycles Simplify the Dynamics of the Endogenous Circadian Oscillator--take the time series of body temperature records as an example

Lin, F.

10.1101/2024.05.09.593452 — biophysics — Posted on 2024-07-16

2754 TCMNP: a data processing and visualization database and R package for traditional Chinese medicine network pharmacology

Liu, J.; Feng, J.; Wu, B.; Ying, M.

10.1101/2024.07.13.601094 — bioinformatics — Posted on 2024-07-16

2755 Diverse Genomic Embedding Benchmark for functional evaluation across the tree of life

West-Roberts, J.; Kravitz, J.; Jha, N.; Cornman, A.; Hwang, Y.

10.1101/2024.07.10.602933 — bioinformatics — Posted on 2024-07-16

2756 Identification of Southeast Asian Anopheles mosquito species with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a cross-correlation approach

Chaumeau, V.; Sawasdichai, S.; Min, T. Z. M. M. M.; Kulabkeeree, T.; Jaruwan, N.; Gloria, N.; Yu Lee, N.; Trackoolchengkaew, M.; Phanaphadungtham, M.; Rongthong, P.; Inta, A.; Watthanaworawit, W.; Nosten, F.

10.1101/2024.07.10.602996 — bioinformatics — Posted on 2024-07-16

2757 I2Bot: an open-source tool for multi-modal and embodied simulation of insect navigation

Sun, X.; Mangan, M.; Yue, S.; Peng, J.

10.1101/2024.07.11.603012 — animal behavior and cognition — Posted on 2024-07-16

2758 Wind Gates Olfaction Driven Search States in Free Flight

Stupski, S. D.; van Breugel, F.

10.1101/2023.11.30.569086 — animal behavior and cognition — Posted on 2024-07-16

2759 Influence of salinity on the thermal tolerance of aquatic organisms

Farias, L.; Beszteri, B.; Castellanos, A.; Doliwa, A.; Enss, J.; Feld, C.; Grabner, D.; Lampert, K.; Mayombo, S.; Prati, S.; Schuerings, C.; Smollich, E.; Schaefer, R.; Sures, B.; Le, Y. T. T.

10.1101/2024.07.11.603038 — ecology — Posted on 2024-07-16

2760 Changing feeding levels reveal plasticity in elasmobranch life history strategies

Lucas, S.; Berggren, P.; Barrowclift, E.; Smallegange, I. M.

10.1101/2024.07.11.601909 — ecology — Posted on 2024-07-16

2761 Metacollinia emscheri n. sp., a novel sanguicolous apostome ciliate of freshwater amphipods (Gammarus spp.)

Prati, S.; Rueckert, S.; Grabner, D.; Sures, B.; Bojko, J.

10.1101/2024.07.10.602951 — ecology — Posted on 2024-07-16

2762 Hemogenic endothelium of the vitelline and umbilical arteries is the major contributor to mouse fetal lympho-myelopoiesis

Barone, C.; Quattrini, G.; Orsenigo, R.; Timoteo-Ferreira, F.; Muratore, A.; Cazzola, A.; Patelli, A.; Soares-da-Silva, F.; Nicholls, M.; Mauri, M.; Bombelli, S.; De Marco, S.; D'Aliberti, D.; Spinelli, S.; Bonalume, V.; Domingues, A.; Sala, G.; Colonna, A.; D'Errico, E.; D'Orlando, C.; Bianchi, C.; Perego, R. A.; Meneveri, R.; de Bruijn, M.; Cumano, A.; Fantin, A.; Brunelli, S.; Piazza, R.; Azzoni, E.

10.1101/2024.07.11.603050 — developmental biology — Posted on 2024-07-16

2763 Fundamental parameters governing the transmission of conjugative plasmids

Rodriguez-Grande, J.; Ortiz, Y.; Garcillan-Barcia, M. d. P.; de la Cruz, F.; Fernandez, R.

10.1101/2023.07.11.548640 — microbiology — Posted on 2024-07-16

2764 Determining potential immunomodulatory drug efficacy in sepsis using ELISpot

Walton, A. H.; Mazer, M. B.; Remy, K. E.; Davitt, E. B.; Griffith, T. S.; Gould, R. W.; Badovinac, V. P.; Brakenridge, S. C.; Drewry, A. M.; Loftus, T. J.; Efron, P. A.; Moldawer, L. L.; Caldwell, C. C.; Hotchkiss, R. S.

10.1101/2024.07.10.602970 — immunology — Posted on 2024-07-16

2765 Gut-specific H3R signaling orchestrates microglia-dependent resolution of peripheral inflammation

Duerholz, K.; Linnerbauer, M.; Schmid, E.; Danzer, H.; Loesslein, L.; Amend, L.; Ehnes, L.; Frech, M.; Azizov, V.; Schaelter, F.; Gessner, A.; Lucas, S.; Lesker, T.-R.; Taudte, R. V.; Hofmann, J.; Beyer, F.; Bootz-Maoz, H.; Reich, Y.; Romano, H.; Mauro, D.; Beckervordersandvorth, R.; Xiang, W.; Haghikia, A.; Akdis, C. A.; Ciccia, F.; Baeuerle, T.; Sarter, K.; Strowig, T.; Yissachar, N.; Schett, G.; Rothhammer, V.; Zaiss, M. M.

10.1101/2024.07.11.603031 — immunology — Posted on 2024-07-16

2766 MAGE-A4-Responsive Plasma Cells Promote Non-Small Cell Lung Cancer

Armstrong, D.; Chang, C.-Y.; Hong, M. J.; Green, L. K.; Hudson, W.; Shen, Y.; Song, L.-Z.; Jammi, S.; Casal, B.; Creighton, C. J.; Carisey, A.; Zhang, X.; McKenna, N.; Kang, S.; Lee, H.-S.; Corry, D.; Kheradmand, F.

10.1101/2024.07.10.602985 — immunology — Posted on 2024-07-16

2767 Measuring the Immune Memory Response of In Vitro Polarized Th1, Th2, and Th17 Cells in the Face of OVA Transgenic Leishmania major in Mouse Model

Tedla, M. G.; Nahar, M. F.; Every, A. L.; Scheerlinck, J.-P. Y.

10.1101/2024.07.10.601391 — immunology — Posted on 2024-07-16

2768 H105A peptide eye drops promote photoreceptor survival in murine and human models of retinal degeneration

Bernardo-Colon, A.; Bighinati, A.; Parween, S.; Debnath, S.; Piano, I.; Adani, E.; Corsi, F.; Gargini, C.; Vergara, N.; Marigo, V.; Becerra, S. P.

10.1101/2024.07.10.602890 — neuroscience — Posted on 2024-07-16

2769 Sequential Transitions of Male Sexual Behaviours Driven by Dual Acetylcholine-Dopamine Dynamics

Miyasaka, A.; Kanda, T.; Nonaka, N.; Terakoshi, Y.; Cherasse, Y.; Ishikawa, Y.; Li, Y.; Takizawa, H.; Seita, J.; Yanagisawa, M.; Sakurai, T.; Sakurai, K.; Liu, Q.

10.1101/2023.12.21.572798 — neuroscience — Posted on 2024-07-16

2770 Beyond Static Models: The Dynamic Interplay of Facial Emotions and Attentional Scope

Hu, K.; He, S.; Li, Q.; Li, C.-S.

10.1101/2024.07.15.603432 — neuroscience — Posted on 2024-07-16

2771 APP beta-CTF triggers cell-autonomous synaptic toxicity independent of Abeta

Luo, M.; Zhou, J.; Sun, C.; Chen, W.; Fu, C.; Si, C.; Zhang, Y.; Geng, Y.; Chen, Y.

10.1101/2024.07.11.603028 — neuroscience — Posted on 2024-07-16

2772 WITHDRAWN: Immune regulators EDS1 and PAD4 constrain ADR1-dependent disease resistance in rice

Fernandes, J.; Wang, J.; Su, R.; Lee, T.; Zheng, Z.; Perin, S.; Cesari, S.; Jalilian, A.; Sciallano, C.; Szurek, B.; Cui, H.; Kroj, T.; Parker, J. E.

10.1101/2024.04.08.588512 — plant biology — Posted on 2024-07-16

2773 WITHDRAWN: Impaired Mitochondrial Calcium Homeostasis Induces Failed Remodeling of the Spiral Artery in Preeclampsia

Lu, X.; Wang, Y.; Zou, Z.

10.1101/2023.10.18.563019 — pathology — Posted on 2024-07-16

2774 CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression

Jonsson, G.; Hofmann, M.; Mereiter, S.; Hartley-Tassell, L.; Sakic, I.; Oliveira, T.; Hoffmann, D.; Novatchkova, M.; Schleiffer, A.; Penninger, J. M.

10.1101/2024.07.08.602586 — cancer biology — Posted on 2024-07-16

2775 Connecting Chromatin Structures to Gene Regulation Using Dynamic Polymer Simulations

Fu, Y.; Zhao, T.; Clark, F. T.; Nomikou, S.; Tsirigos, A.; Lionnet, T.

10.1101/2023.11.07.566032 — biophysics — Posted on 2024-07-16

2776 A universal residue numbering scheme for the Immunoglobulin-fold (Ig-fold) to study Ig-Proteomes and Ig-Interactomes

Tawfeeq, C.; Wang, J.; Khaniya, U.; Madej, T.; Song, J.; Abrol, R.; Youkharibache, P.

10.1101/2024.06.10.598201 — bioinformatics — Posted on 2024-07-16

2777 WITHDRAWN: ToxVec: Deep Language Model-Based Representation Learning for Venom Peptide Classification

Ahmadi, M.; Jahed-Motlagh, M. R.; Asgari, E.; Torkaman Rahmani, A.; McHardy, A. C.

10.1101/2020.09.29.319046 — bioinformatics — Posted on 2024-07-16

2778 Prophage-DB: A comprehensive database to explore diversity, distribution, and ecology of prophages

Dieppa-Colon, E.; Martin, C.; Anantharaman, K.

10.1101/2024.07.11.603044 — bioinformatics — Posted on 2024-07-16

2779 Topological data analysis based on mixed-solvent molecular dynamics simulations enhance cryptic pocket detection

Koseki, J.; Motono, C.; Yanagisawa, K.; Kudo, G.; Yoshino, R.; Hirokawa, T.; Imai, K.

10.1101/2024.07.10.602991 — bioinformatics — Posted on 2024-07-16

2780 Astrocyte-Derived Exosomes Regulate Sperm miR-34c Levels to Mediate the Transgenerational Effects of Paternal Chronic Social Instability Stress

Champroux, A.; Sadat-Shirazi, M.; Chen, X.; Yang, Y.; Feig, L.

10.1101/2024.06.17.599336 — genetics — Posted on 2024-07-16

2781 Downscaling mutualistic networks from species to individuals reveals consistent interaction niches and roles within plant populations

Quintero, E.; Arroyo-Correa, B.; Isla, J.; Rodriguez-Sanchez, F.; Jordano, P.

10.1101/2024.02.02.578595 — ecology — Posted on 2024-07-16

2782 Lineage-based scaling of germline intercellular bridges during oogenesis

Shaikh, U.; Sherlock, K.; Wilson, J.; Gilliland, W.; Lewellyn, L.

10.1101/2023.08.18.553876 — developmental biology — Posted on 2024-07-16

2783 Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to GDNF secretion

Yang, L.; Lin, Z.; Mu, R.; Wu, W.; Zhi, H.; Liu, X.; Yang, H.; Liu, L.

10.1101/2024.02.07.579396 — cell biology — Posted on 2024-07-16

2784 Sde Proteins Coordinate Ubiquitin Utilization and Phosphoribosylation to Promote Establishment and Maintenance of the Legionella Replication Vacuole

Kotewicz, K. M.; Zhang, M.; Kim, S.; Martin, M. S.; Roy Chowdhury, A.; Tai, A.; Scheck, R.; Isberg, R. R.

10.1101/2023.09.07.553534 — microbiology — Posted on 2024-07-16

2785 Plant-to-plant reactive oxygen signal transmission via a Cuscuta bridge

Fichman, Y.; Pelaez-Vico, M. A.; Mudalige, A.; Lee, H.; Mittler, R.; Park, S.

10.1101/2023.07.13.548730 — plant biology — Posted on 2024-07-16

2786 Daily rhythms in metabolic and locomotor behaviour of prematurely ageing PolgA mice

Mueller, R.; Singh, A.; Kuhn, G. A.; Wehrle, E.; Yilmaz, D.

10.1101/2024.03.27.586233 — physiology — Posted on 2024-07-16

2787 Quantifying "just-right" APC inactivation for colorectal cancer initiation

Brunet Guasch, M.; Feeley, N.; Soriano, I.; Thorn, S.; Tomlinson, I.; Nicholson, M.; Antal, T.

10.1101/2024.07.10.602868 — cancer biology — Posted on 2024-07-16

2788 Massively parallel free energy calculations for in silico affinity maturation of designed miniproteins

Novack, D.; Zhang, S.; Voelz, V. A.

10.1101/2024.05.17.594758 — biophysics — Posted on 2024-07-16

2789 Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos

Li, X.; Huebner, R. J.; Williams, M. L. K.; Sawyer, J.; Peifer, M.; Wallingford, J. B.; Thirumalai, D.

10.1101/2024.07.11.603175 — biophysics — Posted on 2024-07-16

2790 Improved prediction of stabilizing mutations in proteins by incorporation of mutational effects on ligand binding

Ganesan, S.; Mittal, N.; Bhat, A.; Adiga, R. S.; Ganesan, A.; Nagarajan, D.; Varadarajan, R.

10.1101/2024.04.11.589149 — biophysics — Posted on 2024-07-16

2791 Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries

Ling, Y. H.; Liang, C.; Wang, S.; Wu, C.

10.1101/2024.07.08.602478 — biophysics — Posted on 2024-07-16

2792 A rapid, accurate approach to inferring pedigrees in endogamous populations

Williams, C. M.; Scelza, B.; Slack, S. D.; Mathias, R. A.; Watson, H.; Barnes, K. C.; Lange, E.; Johnson, R. K.; Gignoux, C. R.; Ramachandran, S.; Henn, B. M.

10.1101/2020.02.25.965376 — bioinformatics — Posted on 2024-07-16

2793 ProTokens: Probabilistic Vocabulary for Compact and Informative Encodings of All-Atom Protein Structures

Lin, X.; Chen, Z.; Li, Y.; Ma, Z.; Fan, C.; Cao, Z.; Feng, S.; Gao, Y. Q.; Zhang, J.

10.1101/2023.11.27.568722 — bioinformatics — Posted on 2024-07-16

2794 Multi-scale Simulations Reveal Molecular Drivers in MUT-16 Scaffold Protein Phase Separations and Client Recognition

Gaurav, K.; Busetto, V.; Moscoso, D. J. P.; Changiarath, A.; Hanson, S. M.; Falk, S.; Ketting, R. F.; Stelzl, L. S.

10.1101/2024.04.13.589337 — bioinformatics — Posted on 2024-07-16

2795 Embryonic piRNAs target horizontally transferred vertebrate transposons in assassin bugs

Brito, T. F. d.; Cardoso, M. A.; Atinbayeva, N.; Brito, I. A. d. A.; da Costa, L. A.; Iovino, N.; Pane, A.

10.1101/2024.01.22.576481 — genomics — Posted on 2024-07-16

2796 The FIGNL1-FIRRM complex is required to complete meiotic recombination in the mouse and prevents massive DNA damage-independent RAD51 and DMC1 loading

Zainu, A.; Dupaigne, P.; Bouchouika, S.; Cau, J.; Clement, J. A. J.; Auffret, P.; Ropars, V.; Charbonnier, J.-B.; de Massy, B.; Mercier, R.; Kumar, R.; Baudat, F.

10.1101/2023.05.17.541096 — genetics — Posted on 2024-07-16

2797 Long-term evolution experiments fully reveal the potential for thermal adaptation

Antunes, M. A.; Grandela, A.; Matos, M.; Simoes, P.

10.1101/2024.02.15.580572 — evolutionary biology — Posted on 2024-07-16

2798 Changes in bird migration phenology over six decades: a perspective from the Neotropical non-breeding grounds

Gutierrez-Carrillo, D. A.; Mateus-Aguilar, B.; Gomez, C.; Cadena, D.

10.1101/2024.02.21.581429 — ecology — Posted on 2024-07-16

2799 Salmonella-induced SIRT1 and SIRT3 are crucial for maintaining the metabolic switch in bacteria and host for successful pathogenesis

Hajra, D.; Rajmani, R. S.; Chakravortty, D.; Chaudhary, A. D.; Gupta, S. K.

10.1101/2022.11.21.517246 — microbiology — Posted on 2024-07-16

2800 The glycoprotein quality control factor Malectin promotes coronavirus replication and viral protein biogenesis

Davies, J. P.; Plate, L.

10.1101/2024.06.02.597051 — microbiology — Posted on 2024-07-16

2801 Pressorum Sensing: Growth-induced Compression Activates cAMP Signaling in Pseudomonas aeruginosa

Ni, L.; Huang, Y.; Huang, Y.; Yu, Y.; Xiong, J.; Wen, H.; Xiao, W.; Liang, H.; Jin, F.

10.1101/2024.07.08.602437 — microbiology — Posted on 2024-07-16

2802 Event-Related Potential Markers of Subjective Cognitive Decline and Mild Cognitive Impairment during a sustained visuo-attentive task

Vergani, A. A.; Mazzeo, S.; Moschini, V.; Burali, R.; Lassi, M.; Amato, L. G.; Carpaneto, J.; Salvestrini, G.; Fabbiani, C.; Giacomucci, G.; Morinelli, C.; Emiliani, F.; Scarpino, M.; Bagnoli, S.; Ingannato, A.; Nacmias, B.; Padiglioni, S.; Sorbi, S.; Bessi, V.; Grippo, A.; Mazzoni, A.

10.1101/2024.01.30.577910 — neuroscience — Posted on 2024-07-16

2803 A novel behavioral paradigm using mice to study predictive postural control

Doi, Y.; Asaka, M.; Born, R. T.; Yanagihara, D.; Uchida, N.

10.1101/2024.07.01.601478 — neuroscience — Posted on 2024-07-16

2804 Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis

Pham, C.; Komaki, Y.; Deas-Just, A.; Le Gac, B.; Mouffle, C.; Franco, C.; Chaperon, A.; Vialou, V.; Tsurugizawa, T.; Cauli, B.; Li, D.

10.1101/2023.10.03.560471 — physiology — Posted on 2024-07-16

2805 Interactive effects of temperature, cadmium, and hypoxia on rainbow trout (Oncorhynchus mykiss) liver mitochondrial bioenergetics

Onukwufor, J. O.; Kamunde, C.

10.1101/2024.07.15.603625 — pharmacology and toxicology — Posted on 2024-07-16

2806 Toxicological evaluation of Vanillin Flavor in E-Liquid Aerosols on Endothelial Cell Function: Findings from the Replica Project

10.1101/2024.01.20.576442 — pharmacology and toxicology — Posted on 2024-07-16

2807 Single-molecule live-cell RNA imaging with CRISPR-Csm

Xia, C.; Colognori, D.; Jiang, X.; Xu, K.; Doudna, J. A.

10.1101/2024.07.14.603457 — biophysics — Posted on 2024-07-16

2808 Inferring Ancestry with the Hierarchical Soft Clustering Approach tangleGen

Burger, K. E.; Klepper, S.; von Luxburg, U.; Baumdicker, F.

10.1101/2024.03.27.586940 — bioinformatics — Posted on 2024-07-16

2809 Feeding status modulates diel vertical migration ofzooplankton via effects on circadian rhythms

Berger, C. A.; Tarrant, A. M.

10.1101/2024.07.12.603318 — animal behavior and cognition — Posted on 2024-07-16

2810 Estimating cis and trans contributions todifferences in gene regulation

Hallgrimsdottir, I. B.; Carilli, M.; Pachter, L.

10.1101/2024.07.13.603403 — genetics — Posted on 2024-07-16

2811 The evolution of an individual-like dispersive stage in colonial siphonophores

Manko, M. K.; Munro, C.; Leclere, L.

10.1101/2024.07.15.603641 — evolutionary biology — Posted on 2024-07-16

2812 Genetic, natal, and spatial drivers of social phenotypes in wild great tits

Satarkar, D.; Sepil, I.; Sheldon, B. C.

10.1101/2024.07.11.603055 — ecology — Posted on 2024-07-16

2813 Limited protection against early-life cytomegalovirus infection results from deficiency of cytotoxic CD8T cells

Fonseca Brito, L.; Ostermann, E.; Perez, A.; Toedter, S.; Virdi, S.; Indenbirken, D.; Glau, L.; Gieras, A.; Brixel, R.; Arens, R.; Grundhoff, A.; Arck, P.; Diemert, A.; Tolosa, E.; Brune, W.; Stahl, F. R.

10.1101/2024.07.10.602923 — immunology — Posted on 2024-07-16

2814 Avirulence depletion assay: combining R gene-mediated selection with bulk sequencing for rapid avirulence gene identification in wheat powdery mildew

Kunz, L.; Jigisha, J.; Menardo, F.; Sotiropoulos, A. G.; Zbinden, H.; Zou, S.; Tang, D.; Hueckelhoven, R.; Keller, B.; Mueller, M. C.

10.1101/2024.07.10.602895 — plant biology — Posted on 2024-07-16

2815 The Microbiota of Moon Snail Egg Collars is Shaped by Host-Specific Factors

Mevers, E.; Piedl, K.; Aylward, F. O.

10.1101/2024.07.10.602920 — bioinformatics — Posted on 2024-07-16

2816 Uneven Walking is Challenging: step-ups or extended steps that is the question

Hosseini-Yazdi, S.-S.

10.1101/2024.07.10.602932 — bioengineering — Posted on 2024-07-16

2817 Genetic and morphological characterization of Metacollinia emscheri n. sp., a novel sanguicolous apostome ciliate of the freshwater amphipods Gammarus pulex and G. fossarum

Prati, S.; Rueckert, S.; Grabner, D.; Sures, B.; Bojko, J.

10.1101/2024.07.10.602951 — ecology — Posted on 2024-07-16

2818 Forecasting the Effects of Global Change on a Bee Biodiversity Hotspot

Buckner, M. A.; Hoge, S. T.; Danforth, B. N.

10.1101/2024.07.10.602956 — ecology — Posted on 2024-07-16

2819 Welcome to Hotel Hymenoptera: monitoring cavity-nesting bee and wasp distribution and their trophic interactions using community science and metabarcoding

Handler, S.; Coveny, K.; Braukmann, T. W. A.; Raine, N. E.; Steinke, D.

10.1101/2024.07.10.602935 — ecology — Posted on 2024-07-16

2820 Quantifying seed rain patterns in a remnant and a chronosequence of restored tallgrass prairies in north central Missouri

Wynne, K. C.; Parker-Smith, M. J.; Murdock, E. M.; Sullivan, L. L.

10.1101/2024.07.10.602969 — ecology — Posted on 2024-07-16

2821 Comparisons of Tree Damage Indicators in Five NASA ABoVE Forest Sites Near Fairbanks, Alaska

Huebner, D. C.; Potter, C. S.

10.1101/2024.07.10.602861 — ecology — Posted on 2024-07-16

2822 Widespread parasite infections in living resident killer whales in the Northeast Pacific Ocean

Mastick, N. C.; Van Cise, A. M.; Parsons, K. M.; Ashe, E.; Williams, R.; Childress, J. N.; Fearnbach, H.; Durban, J.; Emmons, C.; Hanson, B.; Olsen, D.; Wood, C. L.

10.1101/2024.07.10.602791 — ecology — Posted on 2024-07-16

2823 EPHA1 and EPHB4 tyrosine kinase receptors regulate epithelial morphogenesis

Lavoie, N.; Scribe, A.; Chartier, F. J.; Ghani, K.; Jette, A.; Banerjee, S. L.; Caruso, M.; Laurin, M.; Freywald, A.; Elowe, S.; Laprise, P.; Bisson, N.

10.1101/2024.07.15.603563 — cell biology — Posted on 2024-07-16

2824 The initiation and early development of apical-basal polarity in Toxoplasma gondii

Arias Padilla, L. F.; Lopez, J. M.; Shibata, A.; Murray, J. M.; Hu, K.

10.1101/2024.07.14.603470 — cell biology — Posted on 2024-07-16

2825 An off-lattice discrete model to characterise filamentous yeast colony morphology

Li, K.; Green, E.; Tronnolone, H.; Tam, A.; Black, A.; Gardner, J.; Sundstrom, J.; Jiranek, V.; Binder, B.

10.1101/2024.07.14.603473 — cell biology — Posted on 2024-07-16

2826 A distant TANGO1 family member promotes vitellogenin export from the ER in C. elegans

Mo, J. H.; Zhai, C.; Jung, K.; Li, Y.; Yan, Y.; Dong, M.-Q.; Mak, H. Y.

10.1101/2024.07.15.603539 — cell biology — Posted on 2024-07-16

2827 Pharmacological Antagonism of Ccr2+ Cell Recruitment to Facilitate Regenerative Tendon Healing

Smolyak, G.; Rodenhouse, A.; Nichols, A. E.; Ketonis, C.; Loiselle, A. E.

10.1101/2024.07.15.603448 — cell biology — Posted on 2024-07-16

2828 Small molecule FICD inhibitors suppress endogenous and pathologic FICD-mediated protein AMPylation

Chatterjee, B.; Alam, M.; Chakravorty, A.; Lacy, S.; Rech, J.; Brooks, C. L.; Arvan, P.; Truttmann, M.

10.1101/2024.07.13.603377 — cell biology — Posted on 2024-07-16

2829 The native glycocalyx is an ordered, self-assembled hierarchical micro- and nanoarray lamellar structure conserved in evolution

Garbarino, E.; Subbiahdoss, G.; Scheberl, A.; Reimhult, E.; Misevic, G.

10.1101/2024.07.15.603518 — cell biology — Posted on 2024-07-16

2830 Local nuclear to cytoplasmic ratio regulates chaperone-dependent H3 variant incorporation during zygotic genome activation

Bhatt, A. D.; Brown, M. G.; Wackford, A. B.; Shindo, Y.; Amodeo, A. A.

10.1101/2024.07.15.603602 — cell biology — Posted on 2024-07-16

2831 A second wave of Notch signaling diversifies the intestinal secretory lineage

Zagoren, E.; Dias, N.; Smith, Z. D.; Ameen, N. A.; Sumigray, K.

10.1101/2024.07.15.603542 — cell biology — Posted on 2024-07-16

2832 Novel Imaging Tools to Study Mitochondrial Dynamics in Caenorhabditis elegans

Valera-Alberni, M.; Yao, P.; Romero-Sanz, S.; Lanjuin, A.; Mair, W. B.

10.1101/2024.07.16.603730 — cell biology — Posted on 2024-07-16

2833 Unbiased functional genetic screens reveal essential RNA modifications in human cancer and drug resistance

Pauli, C.; Kienhoefer, M.; Blank, M.; Begik, O.; Rohde, C.; Heid, D.; Xu, F.; Zimmermann, S. M. N.; Weidenauer, K.; Delaunay, S.; Krall, N.; Trunk, K.; Zhao, D.; Zhou, F.; Heit-Mondrzyk, A.; Platzbecker, U.; Baldus, C.; Serve, H.; Bornhaeuser, M.; Vagbo, C. B.; Aznar Benitah, S.; Krijgsveld, J.; Novoa, E. M.; Mueller-Tidow, C.; Frye, M.

10.1101/2024.07.13.603368 — cell biology — Posted on 2024-07-16

2834 Senescent cells cluster CTCF on nuclear speckles to sustain their splicing program

Palikyras, S.; Varamogianni-Mamatsi, V.; Zhu, Y.; Ramasamy, S.; Mizi, A.; Liebermann, I.; Stavropoulou, A.; Papadionysiou, I.; Bartsch, D.; Kargapolova, Y.; Sofiadis, K.; Nikolaou, C.; Kurian, L.; Oudelaar, M.; Barbieri, M.; Papantonis, A.

10.1101/2024.07.16.603680 — cell biology — Posted on 2024-07-16

2835 A linear ontogeny accounts for the development of naive, memory and tumour-infiltrating regulatory T cells in mice

Pathak, S.; Hogan, T.; rane, S.; Huang, Y.; Sinclair, C.; Barry, S.; Carnevalli, L.; Yates, A.; Seddon, B.

10.1101/2024.07.10.602914 — immunology — Posted on 2024-07-16

2836 A reaction norm for flowering time plasticity reveals physiological footprints of maize adaptation

Drouault, J.; Palaffre, C.; Millet, E. J.; Rodriguez, J.; Martre, P.; Johnson, K.; Parent, B.; Welcker, C.; Wisser, R. J.

10.1101/2024.07.10.602692 — plant biology — Posted on 2024-07-16

2837 Two for tau: Automated model discovery reveals two-stage tau aggregation dynamics in Alzheimer's disease

Stockman, C. A.; Goriely, A.; Kuhl, E.

10.1101/2024.07.15.603581 — biophysics — Posted on 2024-07-16

2838 Sequence-specific targeting of intrinsically disordered protein regions

Wu, K.; Jiang, H.; Hicks, D. R.; Liu, C.; Muratspahic, E.; Ramelot, T. A.; Liu, Y.; McNally, K.; Gaur, A.; Coventry, B.; Chen, W.; Bera, A. K.; Kang, A.; Gerben, S.; Lamb, M. Y.-L.; Murray, A.; Li, X.; Kennedy, M. A.; Yang, W.; Schober, G.; Brierley, S. M.; Gelb, M. H.; Montelione, G. T.; Derivery, E.; Baker, D.

10.1101/2024.07.15.603480 — biochemistry — Posted on 2024-07-16

2839 Actin dynamics sustains spatial gradients of membrane tension in adherent cells

Garcia-Arcos, J. M.; Mehidi, A.; Sanchez Velazquez, J.; Guillamat, P.; Tomba, C.; Houzet, L.; Capolupo, L.; D'Angelo, G.; Colom, A.; Hinde, E.; Aumeier, C.; Roux, A.

10.1101/2024.07.15.603517 — cell biology — Posted on 2024-07-16

2840 Protrudin acts at ER-endosome contacts to promote KIF5-mediated endosomal fission and endosome-to-Golgi transport

Kleniuk, J.; Nadadhur, A. G.; Wolfenden, E.; Rodger, C.; Zlamalova, E.; Reid, E.

10.1101/2024.07.15.602703 — cell biology — Posted on 2024-07-16

2841 Maternal dietary deficiency in choline reduced levels of MMP-2 levels in blood and brain tissue of male offspring mice

Esfandiarei, M.; Strash, G. G.; Covaleski, A.; Ille, S.; Li, W.; Jadavji, N. M.

10.1101/2024.07.15.603575 — neuroscience — Posted on 2024-07-16

2842 BATF2 is a regulator of interferon-gamma signaling in astrocytes during neuroinflammation

Tinkey, R. A.; Smith, B. C.; Habean, M. L.; Williams, J. L.

10.1101/2024.07.10.602938 — neuroscience — Posted on 2024-07-16

2843 Physical activity modulates early visual response and improves target detection in humans

Weischner, T.; Che, X.; Schmid, P. R.; Reichert, C.; Scholz, A.; Knight, R. T.; Duerschmid, S.

10.1101/2024.07.10.602924 — neuroscience — Posted on 2024-07-16

2844 Preclinical validation and kinetic modelling of the SV2A PET ligand UCB-J in mice

Everix, L.; Elvas, F.; Miranda, A.; Khetarpal, V.; Liu, L.; Bard, J.; Staelens, S.; Bertoglio, D.

10.1101/2024.07.10.602899 — neuroscience — Posted on 2024-07-16

2845 Submaximal eccentric resistance training increases serial sarcomere number and improves dynamic muscle performance in old rats

Hinks, A. A.; Vlemmix, E.; Power, G. A.

10.1101/2024.07.10.602916 — physiology — Posted on 2024-07-16

2846 High-throughput drug screening for inhibition of influenza A virus infection based on human SIRT1 promoter and Genipin suppressing influenza A virus by activation of AMPK-SIRT1-PGC-1α signaling pathway

Dai, J.; Ye, J.; Liu, D.; Wang, Q.

10.1101/2024.07.10.602919 — pharmacology and toxicology — Posted on 2024-07-16

2847 MYC Binding Near Transcriptional End Sites Regulates Basal Gene Expression, Read-Through Transcription and Intragenic Contacts

Wang, H.; Ma, B.; Stevens, T.; Knapp, J.; Lu, j.; Prochownik, E. V.

10.1101/2024.07.11.603118 — molecular biology — Posted on 2024-07-16

2848 Investigating the effects of transcutaneous Vagus Nerve Stimulation on motor cortex excitability and inhibition through paired-pulse Transcranial Magnetic Stimulation

Boscarol, S.; Turchi, L.; Oldrati, V.; Urgesi, C.; Finisguerra, A.

10.1101/2024.07.12.603338 — neuroscience — Posted on 2024-07-16

2849 Influence of truthful and misleading instructions on statistical learning across the autism spectrum

Angeletos Chrysaitis, N.; Series, P.

10.1101/2024.07.12.603256 — neuroscience — Posted on 2024-07-16

2850 Characterization of focused ultrasound blood-brain barrier disruption effect on inflammation as a function of treatment parameters

Angolano, C.; Hansen, E.; Ajjawi, H.; Nowlin, P.; Zhang, Y.; Fomin-Thunemann, N.; Ferran, C.; Todd, N.

10.1101/2024.07.10.602776 — neuroscience — Posted on 2024-07-16

2851 Ancient tree-topologies and gene-flow processes among human lineages in Africa

Breton, G.; Sjodin, P.; Zervakis, P. I.; Laurent, R.; Froment, A.; Sjostrand, A. E.; Hewlett, B. S.; Barreiro, L. B.; Perry, G. H.; Soodyall, H.; Heyer, E.; Schlebusch, C. M.; Jakobsson, M.; Verdu, P.

10.1101/2024.07.15.603519 — genetics — Posted on 2024-07-16

2852 Improving biodiversity in Central and Eastern European domestic gardens needs regionally scaled strategies

Varga-Szilay, Z.; Barsevskis, A.; Benedek, K.; Bevk, D.; Jojczyk, A.; Kristin, A.; Ruzickova, J.; Jelaska, L. S.; Veromann, E.; Vilumets, S.; Fetyko, K.; Szovenyi, G.; Pozsgai, G.

10.1101/2024.07.12.603327 — ecology — Posted on 2024-07-16

2853 Biophysical Modeling and Experimental Analysis of the Dynamics of C. elegans Body-Wall Muscle Cells

Du, X.; Crodelle, J.; Barranca, V. J.; Li, S.; Shi, Y.; Gao, S.; Zhou, D.

10.1101/2024.07.15.603498 — neuroscience — Posted on 2024-07-16

2854 Emergent collective alignment gives competitive advantage to longer cells during range expansion

van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.

10.1101/2024.01.26.577059 — biophysics — Posted on 2024-07-16

2855 Controlled and orthogonal partitioning of large particles into biomolecular condensates

Kelley, F.; Ani, A.; Pinlac, E.; Linders, B.; Favetta, B.; Barai, M.; Ma, Y.; Singh, A.; Dignon, G. L.; Gu, Y.; Schuster, B. S.

10.1101/2024.07.11.603072 — biophysics — Posted on 2024-07-16

2856 Effect of molecular weight of tyramine-modified hyaluronan on polarization state of THP-1 and peripheral blood mononuclear cells-derived macrophages

Wychowaniec, J. K.; Bektas, E. I.; Vernengo, A. J.; Mürner, M.; Airoldi, M.; Tipay, P. S.; Sapudom, J.; Teo, J.; Eglin, D.; D'Este, M.

10.1101/2024.01.11.575241 — bioengineering — Posted on 2024-07-16

2857 Glycosaminoglycans act as activators of peptidylarginine deiminase 4

Bereta, G. P.; Bielecka, E.; Marzec, K.; Pijanowski, L.; Biela, A.; Wilk, P.; Kaminska, M.; Nowak, J.; Wator, E.; Grudnik, P.; Kowalczyk, D.; Koziel, J.; Mydel, P.; Poreba, M.; Kantyka, T.

10.1101/2024.06.17.599283 — biochemistry — Posted on 2024-07-16

2858 Palaeoproteomic identification of a whale bone tool from Bronze Age Heiloo, the Netherlands

Dekker, J. A. A.; Mylopotamitaki, D.; Verbaas, A.; Sinet-Mathiot, V.; Presslee, S.; McCarthy, M. L.; Olsen, M. T.; Olsen, J. V.; van den Hurk, Y.; Brattinga, J.; Welker, F.

10.1101/2024.04.15.589626 — evolutionary biology — Posted on 2024-07-16

2859 Shaping and interpretation of Dpp morphogen gradient by endocytic trafficking

Rasouliha, S. H.; Aguilar, G.; Reinger, C.; Matsuda, S.

10.1101/2023.03.27.534445 — developmental biology — Posted on 2024-07-16

2860 Comparative genomic analysis of Latilactobacillus sakei strains provides new insights into their association with different niche adaptations

Ito, K.; Ito, Y.

10.1101/2024.07.15.603503 — microbiology — Posted on 2024-07-16

2861 Dimeric assembly of F1-like ATPase for Mycoplasma gliding motility

Toyonaga, T.; Kato, T.; Kawamoto, A.; Miyata, T.; Kawakami, K.; Fujita, J.; Hamaguchi, T.; Namba, K.; Miyata, M.

10.1101/2024.06.11.597861 — microbiology — Posted on 2024-07-16

2862 PIM kinase control of CD8 T cell protein synthesis and cell trafficking

Marchingo, J. M.; Spinelli, L.; Pathak, S.; Cantrell, D. A.

10.1101/2024.03.25.586560 — immunology — Posted on 2024-07-16

2863 Data-driven model of glycolysis shows that allostery maintains high ATP levels while mass action controls flux and energy of ATP hydrolysis

Choe, M.; Einav, T.; Phillips, R.; Titov, D. V.

10.1101/2022.12.28.522046 — systems biology — Posted on 2024-07-16

2864 Uncertainty-Aware Traction Force Microscopy

Kandasamy, A.; Yeh, Y.-T.; Serrano, R.; Mercola, M.; del Alamo, J. C.

10.1101/2024.07.05.602172 — biophysics — Posted on 2024-07-16

2865 ADELLE: A global testing method for Trans-eQTL mapping

Akinbiyi, T.; McPeek, M. S.; Abney, M.

10.1101/2024.02.24.581871 — genetics — Posted on 2024-07-16

2866 Hatcheries to high seas: climate change connections to salmon marine survival

Kitada, S.; Myers, K. W.; Kishino, H.

10.1101/2023.09.18.558187 — evolutionary biology — Posted on 2024-07-16

2867 A comprehensive review of South Australia's Great Artesian Basin spring and discharge wetlands biota

Beasley-Hall, P. G.; Hedges, B. A.; Cooper, S. J. B.; Austin, A. D.; Guzik, M. T.

10.1101/2023.10.29.564639 — ecology — Posted on 2024-07-16

2868 SARS-CoV-2 entry and fusion are independent of ACE2 localization to lipid rafts

Bolland, W.; Buchrieser, J.; Schwartz, O.; Casartelli, N.; Porrot, F.; Guivel-Benhassine, F.; Marechal, I.; Petiot, C.

10.1101/2024.07.13.603361 — microbiology — Posted on 2024-07-16

2869 Secondary metabolites and their impact on symbiotic interactions in the ambrosia fungus Geosmithia eupagioceri

Kolarik, M.; Stodulkova, E.; Kajzrova, S.; Semerad, J.; Hubert, J.; Kuzma, M.; Sulc, M.; Cisarova, I.; Jasica, A.; Wennrich, J.-P.; Hulcr, J.; Flieger, M.

10.1101/2024.07.15.603585 — microbiology — Posted on 2024-07-16

2870 Endogenous ZAP affects Zika virus RNA interactome

Sabir, A. J.; Le, N. P. K.; Singh, P. P.; Karniychuk, U.

10.1101/2024.05.23.595534 — microbiology — Posted on 2024-07-16

2871 Astrocyte-induced firing in primary afferent axons

Gaudel, F.; Giraud, J.; Morquette, P.; Couillard-Larocque, M.; Verdier, D.; Kolta, A.

10.1101/2024.06.07.597942 — neuroscience — Posted on 2024-07-16

2872 Not All Is Lost: Resilience of Microbiome Samples to Freezer Failures and Long-term Storage

Pulido-Chavez, M. F.; Glassman, S.; Randolph, J. W. J.

10.1101/2024.07.15.603584 — microbiology — Posted on 2024-07-15

2873 Mutational and evolutionary dynamics of non-structural and spike proteins from variants of concern (VOC) ofSARS-CoV-2 in India

Chaudhuri, A.; Das, S.; Chakrabarti, S.

10.1101/2024.07.14.603481 — bioinformatics — Posted on 2024-07-15

2874 Rate variation and recurrent sequence errors in pandemic-scale phylogenetics

De Maio, N.; Willemsen, M.; Guo, Z.; Saha, A.; Hunt, M.; Ly-Trong, N.; Minh, B. Q.; Iqbal, Z.; Goldman, N.

10.1101/2024.07.12.603240 — bioinformatics — Posted on 2024-07-15

2875 Enzymatic carbon-fluorine bond cleavage by human gut microbes

Probst, S. I.; Felder, F. D.; Poltorak, V.; Mewalal, R.; Blaby, I. K.; Robinson, S. L.

10.1101/2024.07.15.601322 — biochemistry — Posted on 2024-07-15

2876 p16High immune cell - controlled disease tolerance as a broad defense and healthspan extending strategy

Triana-Martinez, F.; Pierantoni, A.; Graca, D.; Bergo, V.; Emelyanov, A.; Grigorash, B.; Tsuji, S.; Nakano, S.; Grosse, L.; Brglez, V.; Marty, P.; Dellamonica, J.; Fornace, A. J.; Trompouki, E.; Eiji, H.; Seitz-Polski, B.; Bulavin, D. V.

10.1101/2024.07.15.603540 — cell biology — Posted on 2024-07-15

2877 Molecular Landscape of Modality-Specific Exercise Adaptation in Human Skeletal Muscle through Large-Scale Multi-OMICs Integration

Jacques, M.; Landen, S.; Sharples, A. P.; Garnham, A.; Schittenhelm, R.; Stele, J.; Heikkinen, A.; Sillanpaa, E.; Ollikainen, M.; Broatch, J.; Zarekookandeh, N.; Hanson, O.; Ekstrom, O.; Asplund, O.; Lamon, S.; Alexander, S. E.; Smith, C.; Bauer, C.; Woessner, M. N.; Levinger, I.; Teschendorff, A. E.; Gillberg, L.; Blom, I.; Wulff Helge, J.; Harvey, N. R.; Haupt, L. M.; Griffiths, L. R.; Deshmukh, A. S.; Pietilainen, K. H.; Piirila, P.; Seaborne, R. A.; Jones-Freeman, B.; EYNON, N.

10.1101/2024.07.14.603458 — molecular biology — Posted on 2024-07-15

2878 The Splice Index as a prognostic biomarker of strength and function in myotonic dystrophy type 1

Provenzano, M.; Ikegami, K.; Bates, K.; Gaynor, A.; Hartman, J. M.; Jones, A. S.; Butler, A.; Berggren, K. N.; Dekdebrun, J.; Hung, M.; Lapato, D. M.; Kiefer, M.; Thornton, C.; Johnson, N. E.; Hale, M. A.

10.1101/2024.07.10.602610 — molecular biology — Posted on 2024-07-15

2879 Comparative genomic analysis of Latilactobacillus sakei strains provides new insights into their association with different niche adaptations

Ito, K.; Ito, Y.

10.1101/2024.07.15.603503 — microbiology — Posted on 2024-07-15

2880 2,3-bis (phenylamino) quinoxaline - containing compounds display potent activity against Methicillin-resistant Staphylococcus aureus, Enterococcus faecalis and their biofilms

Padalino, G.; Duggan, K.; Mur, L.; Millard, J.-Y.; Brancale, A.; Hoffmann, K. F.

10.1101/2024.07.15.603556 — microbiology — Posted on 2024-07-15

2881 Transcriptomic Insights into the Virulence of Acinetobacter baumannii During Infection: Role of Iron Uptake and Siderophore Production Genes

Ten, K. E.; Rahman, S.; Tan, H. S.

10.1101/2024.07.15.603485 — microbiology — Posted on 2024-07-15

2882 Trace elements increase reproducibility of microbial growth

Shimoga Nadig, A.; Gross, R.; Bollenbach, T.; Ansmann, G.

10.1101/2024.07.15.603609 — microbiology — Posted on 2024-07-15

2883 Efficacy and mechanism of actions of cipargamin as an antibabesial drug candidate

Li, H.; Ji, S.; Ariefta, N. R.; Galon, E. M. S.; El-Sayed, S. A.; Jia, L.; Nishikawa, Y.; Liu, M.; Xuan, X.

10.1101/2024.07.15.603500 — microbiology — Posted on 2024-07-15

2884 Modelling interactions that determine core gut microbiome stability to predict microbiome perturbation by opportunistic pathogens

van Leeuwen, P. T.; Brul, S.; Seppen, J.; Wortel, M. T.

10.1101/2024.07.15.603569 — microbiology — Posted on 2024-07-15

2885 Metabolic conservation by protein quality control in Campylobacter jejuni underlies the antibiotic tolerance

Feng, J.; Li, S.; Hu, Y.; Stahl, M.; Ma, L.; Knuff-Janzen, K.; Wang, K.; Hua, M. Z.; Vallance, B. A.; Konkel, M. E.; Finlay, B. B.; Lu, X.

10.1101/2024.07.15.603561 — microbiology — Posted on 2024-07-15

2886 Structural insight into sodium ion pathway in the bacterial flagellar stator from marine Vibrio

Nishikino, T.; Takekawa, N.; Kishikawa, J.-i.; Hirose, M.; Kojima, S.; Homma, M.; Kato, T.; Imada, K.

10.1101/2024.07.15.603494 — microbiology — Posted on 2024-07-15

2887 Electrochemical cofactor recycling of bacterial microcompartments

Sutter, M.; Utschig, L. M.; Niklas, J.; Paul, S.; Kahan, D. N.; Gupta, S.; Poluektov, O. G.; Ferlez, B.; Tefft, N. M.; TerAvest, M. A.; Hickey, D. P.; Vermaas, J. V.; Ralston, C. Y.; Kerfeld, C. A.

10.1101/2024.07.15.603600 — microbiology — Posted on 2024-07-15

2888 Biofilm dispersal patterns revealed using far-red fluorogenic probes

Prentice, J. A.; Kasivisweswaran, S.; van de Weerd, R.; Bridges, A. A.

10.1101/2024.07.15.603607 — microbiology — Posted on 2024-07-15

2889 Laboratory evolution of the bacterial genome structure through insertion sequence activation

Kanai, Y.; Shibai, A.; Yokoi, N.; Tsuru, S.; Furusawa, C.

10.1101/2024.07.14.599650 — microbiology — Posted on 2024-07-15

2890 Single-Cell and Spatial Transcriptomic Analyses Deciphering the Three-Layer Architecture of Human Tuberculosis Granulomas

Yu, X.; Wang, J.; Wang, P.; Liu, X.; Li, C.; Ju, Y.; Liu, S.; Dong, Y.; Wang, J.; Tuohetaerbaike, B.; Wen, H.; Zhang, W.; Niu, H.; Xu, S.; Jiang, C.; Jiang, X.; Wu, J.; Huang, H.; Chen, F.

10.1101/2024.07.15.603490 — microbiology — Posted on 2024-07-15

2891 The bacterial microbiome in Spider and Deathwatch beetles

Hendricks, A.; Philips, T. K.; Plarre, R.; Engl, T.; Martinson, V. G.

10.1101/2024.07.15.603335 — microbiology — Posted on 2024-07-15

2892 Gradient Oriented Active Learning for Candidate Drug Design

Medabalimi, V.

10.1101/2024.07.11.603160 — synthetic biology — Posted on 2024-07-15

2893 Genetic manipulation of Bacteriophage T4 utilizing the CRISPR-Cas13b system

Bhoobalan-Chitty, Y.; Stouf, M.; De-paepe, M.

10.1101/2024.07.15.603621 — synthetic biology — Posted on 2024-07-15

2894 Supervised Deep Learning with Gene Annotation for Cell Classification

Lin, Z.; Sun, W.

10.1101/2024.07.15.603527 — bioinformatics — Posted on 2024-07-15

2895 Restoring data balance via generative models of T-cell receptors for antigen-binding prediction

Loffredo, E.; Pastore, M.; Cocco, S.; Monasson, R.

10.1101/2024.07.10.602897 — bioinformatics — Posted on 2024-07-15

2896 Coordinated Response Modulations Enable Flexible Use of Visual Information

Srinath, R.; Czarnik, M. M.; Cohen, M. R.

10.1101/2024.07.10.602774 — neuroscience — Posted on 2024-07-15

2897 Physical Exercise Improves Working Memory through Ripple-Spindle Coupling

Che, X.; Auer, B.; Schmid, P.; Reichert, C.; Scholz, A.; Weischner, T.; Knight, R. T.; Duerschmid, S.

10.1101/2024.07.10.602896 — neuroscience — Posted on 2024-07-15

2898 Digital pathology assessment of kidney glomerular filtration barrier ultrastructure in an animal model of podocytopathy

Laudon, A. D.; Wang, Z.; Zou, A.; Sharma, R.; Ji, J.; Kim, C.; Qian, Y.; Ye, Q.; Chen, H.; Henderson, J. M.; Zhang, C.; Kolachalama, V. B.; Lu, W.

10.1101/2024.06.14.599097 — pathology — Posted on 2024-07-15

2899 Advancing Early Diagnosis of Alzheimers Disease: A Paper-Based Aptasensor for Detecting Amyloid Beta(1-42) and p-tau181 from Plasma Using CdTe Quantum Dots

Ahmadli, N.; Balci, E.; Hasirci, U.; Oksuz, S. S.; Alemdar, E.; Yildiz, E. N.; Uludag, I.; Ayyildiz, N.; Kargidan, M.

10.1101/2024.07.10.602686 — bioengineering — Posted on 2024-07-15

2900 3D micropatterned traction force microscopy: a technique to control three-dimensional cell shape while measuring cell-substrate force transmission.

Faure, L. M.; Gomez Gonzalez, M.; Baguer, O.; Comelles, J.; Martinez, E.; Arroyo, M.; Trepat, X.; Roca-Cusachs, P.

10.1101/2024.07.10.602889 — bioengineering — Posted on 2024-07-15

2901 Flower visitation through the lens: Exploring the foraging behaviour of Bombus terrestris with a computer vision-based application

Varga-Szilay, Z.; Szovenyi, G.; Pozsgai, G.

10.1101/2024.07.10.602888 — animal behavior and cognition — Posted on 2024-07-15

2902 The distribution of distances to the edge of species coexistence

DESALLAIS, M.; LOREAU, M.; ARNOLDI, J.-F.

10.1101/2024.01.21.575550 — ecology — Posted on 2024-07-15

2903 Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice

Wang, N.; Zhang, S.; Langfelder, P.; Ramanathan, L.; Plascencia, M.; Gao, F.; Vaca, R.; Gu, X.; Ferguson, L. D.; Dionisio, L. E.; Prasad, B. C.; Vogt, T. F.; Horvath, S.; Aaronson, J.; Rosinski, J.; Yang, X. W.

10.1101/2024.07.09.602815 — neuroscience — Posted on 2024-07-15

2904 Contextual AI models for single-cell protein biology

Li, M. M.; Huang, Y.; Sumathipala, M.; Liang, M. Q.; Valdeolivas, A.; Ananthakrishnan, A. N.; Liao, K.; Marbach, D.; Zitnik, M.

10.1101/2023.07.18.549602 — bioinformatics — Posted on 2024-07-15

2905 Red blood cell dynamics during malaria infection challenge the assumptions of mathematical models of infection dynamics

Peters, M. A. E.; King, A. A.; Wale, N.

10.1101/2024.01.10.575051 — microbiology — Posted on 2024-07-15

2906 Comprehensive multi-site profiling of the malignant pleural mesothelioma micro-environment identifies candidate molecular determinants of histopathologic type

Severson, D. T.; Freyaldenhoven, S.; Wadowski, B.; Hughes, T.; Hung, Y. P.; Chirieac, L.; Jensen, R. V.; Richards, W. G.; Sedak, A. A.; Gustafson, C. E.; Vermilya, K.; Innocenti, S.; Korle, S.; Barlow, J. S.; Couger, M. B.; Anderson, J.; Meyervitz, J.; Wang, V.; Dao, M. N.; Shalek, A. K.; De Rienzo, A.; Bueno, R.

10.1101/2024.05.24.595690 — cancer biology — Posted on 2024-07-15

2907 Isoginkgetin and Madrasin are poor splicing inhibitors

Tellier, M.; Ansa, G.; Murphy, S.

10.1101/2023.01.16.524270 — molecular biology — Posted on 2024-07-15

2908 Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acathamoeba castellanii protozoa

Graham, C. I.; Gierys, A. J.; MacMartin, T. L.; Penner, T. V.; Beck, J. C.; Prehna, G.; de Kievit, T. R.; Brassinga, A. K. C.

10.1101/2024.07.09.602712 — microbiology — Posted on 2024-07-15

2909 Mast Cell Derived Histamine Negatively Regulates Hematopoiesis

Klein, B. R.; Smith, J. N. P.; Katabathula, R.; Chaudhary, R.; Gao, Z.; Cordova, B. A.; Petroze, F.; Tiwari, R.; Gerson, S. L.; Xu, R.; Markowitz, S. D.; Desai, A. B.

10.1101/2022.02.03.479012 — immunology — Posted on 2024-07-15

2910 Oxidized LDL regulates efferocytosis through the CD36-PKM2-mtROS pathway

Zhang, J.; Chang, J.; Chen, V.; Beg, M. A.; Huang, W.; Vick, L.; Wang, Y.; Zhang, H.; Yttre, E.; Gupta, A.; Castleberry, M.; Zhang, Z.; Dai, W.; Song, S.; Zhu, J.; Yang, M.; Brown, A. K.; Xu, Z.; Ma, Y.-q.; Smith, B. C.; Zielonka, J.; Taylor, J. G.; Dhaou, C. B.; Orr, A. W.; Cui, W.; Zheng, Z.; Chen, Y.

10.1101/2023.09.07.556574 — immunology — Posted on 2024-07-15

2911 Different subregions of monkey lateral prefrontal cortex respond to abstract sequences and their components

Rodriguez, N. Y.; Ahuja, A.; Basu, D.; McKim, T. H.; Desrochers, T. M.

10.1101/2024.02.13.580192 — neuroscience — Posted on 2024-07-15

2912 Longitudinal Multi-Tensor Analysis of Neocortical Microstructure in an Animal Model of Cortical Dysplasia

Villasenor, P. J.; Luna-Munguia, H.; Ramirez-Manzanares, A.; Coronado-Leija, R.; Concha, L.

10.1101/2024.07.09.602800 — neuroscience — Posted on 2024-07-15

2913 A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.

Tolossa, G. B.; Schneider, A. M.; Dyer, E. L.; Hengen, K. B.

10.1101/2024.07.11.603152 — neuroscience — Posted on 2024-07-15

2914 Parietal alpha stimulation causally enhances attentional information coding in evoked and oscillatory activity

Lu, R.; Michael, E.; Scrivener, C. L.; Jackson, J. B.; Duncan, J.; Woolgar, A.

10.1101/2023.11.14.567111 — neuroscience — Posted on 2024-07-15

2915 INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement

Schiavon, C. R.; Wang, Y.; Feng, J. W.; Garrett, S.; Dayn, Y.; Sung, T.-C.; Wang, C.; Youle, R. J.; Quintero-Carmona, O. A.; Shadel, G. S.; Manor, U.

10.1101/2024.07.06.602365 — cell biology — Posted on 2024-07-15

2916 CellPie: a scalable spatial transcriptomics factor discovery method via joint non-negative matrix factorization

Georgaka, S.; Morgans, W. G.; Zhao, Q.; Sanchez Martinez, D.; Ali, A.; Ghafoor, M.; Baker, S. M.; Bristow, R.; Iqbal, M.; Rattray, M.

10.1101/2023.09.29.560213 — bioinformatics — Posted on 2024-07-15

2917 Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer

McPherson, A. W.; Vazquez-Garcia, I.; Myers, M. A.; Zatzman, M.; Al-Rawi, D. H.; Weiner, A. C.; Freeman, S. S.; Mohibullah, N.; Satas, G.; Williams, M. J.; Ceglia, N.; Zhang, A. W.; Li, J.; Lim, J. L. P.; Wu, M.; Choi, S.; Havasov, E.; Grewal, D.; Shi, H.; Kim, M.; Schwarz, R. F.; Kaufmann, T. L.; Dinh, K. N.; Uhlitz, F.; Tran, J.; Wu, Y.; Patel, R.; Ramakrishnan, S.; Kim, D.; Clarke, J.; Green, H.; Ali, E.; DiBona, M.; Varice, N.; Kundra, R.; Broach, V.; Gardner, G. J.; Long Roche, K.; Sonoda, Y.; Zivanovic, O.; Kim, S. H.; Grisham, R. N.; Liu, Y. L.; Viale, A.; Rusk, N.; Lakhman, Y.; Ellenso

10.1101/2024.07.11.602772 — cancer biology — Posted on 2024-07-15

2918 Chromosomal fusion drives sex chromosome evolution in treehoppers despite long-term X chromosome conservation

Palmer Droguett, D. H.; Fletcher, M.; Kocher, S. D.; Cabral-de-Mello, D. C.; Wright, A.

10.1101/2024.07.12.603334 — evolutionary biology — Posted on 2024-07-15

2919 Reconciling ecology and evolutionary game theory or When not to think cooperation

Tarnita, C.; Traulsen, A.

10.1101/2024.07.10.602961 — evolutionary biology — Posted on 2024-07-15

2920 Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits

Scholes, N. S.; Bertoni, M.; Comajuncosa-Creus, A.; Kladnik, K.; Frommelt, F.; Hinterndorfer, M.; Razumkov, H.; Prokofeva, P.; Schwalm, M. P.; Imrichova, H.; Barone, E.; Schätz, C.; Rukavina, A.; Koren, A.; Kubicek, S.; Knapp, S.; Gray, N. S.; Superti-Furga, G.; Küster, B.; Aloy, P.; Winter, G. E.

10.1101/2024.07.10.602881 — molecular biology — Posted on 2024-07-15

2921 Aperiodic activity as a central neural feature of hypnotic susceptibility outside of hypnosis

Landry, M.; da Silva Castanheira, J.; Boisvert, C.; Rousseaux, F.; Sackur, J.; Raz, A.; Ogez, D.; Rainville, P.; Jerbi, K.

10.1101/2023.11.16.567097 — neuroscience — Posted on 2024-07-15

2922 The Early Dodder Gets the Host: Decoding the Coiling Patterns of Cuscuta campestris with Automated Image Processing

Bentelspacher, M.; Amezquita, E. J.; Adhikari, S.; Barros-Rios, J.; Park, S.

10.1101/2024.02.29.582789 — plant biology — Posted on 2024-07-15

2923 Discovery of Novel Long Non-Coding RNAs That May Potentially Play a Role in Zebrafish Brain Regeneration Post Traumatic Injury

Kohli, S.; Abhilash, D.; Hemlata, H.; Srivastava, P. P.; Kumar, V.; Minocha, S.; Gupta, I.

10.1101/2024.06.03.597135 — bioinformatics — Posted on 2024-07-15

2924 Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy

Guo, M.; Wu, Y.; Hobson, C. M.; Su, Y.; Qian, S.; Krueger, E.; Christensen, R.; Kroeschell, G.; Bui, J.; Chaw, M.; Zhang, L.; Liu, J.; Hou, X.; Han, X.; Lu, Z.; Ma, X.; Zhovmer, A.; Combs, C.; Moyle, M.; Yemini, E.; Liu, H.; Liu, Z.; Benedetto, A.; La Riviere, P.; Colon-Ramos, D.; Shroff, H.

10.1101/2023.10.15.562439 — bioengineering — Posted on 2024-07-15

2925 Morph-linked variation in female pheromone signaling and male response in a polymorphic moth

De Pasqual, C.; Selenius, E.; Burdfield-Steel, E.; Mappes, J.

10.1101/2024.07.13.603243 — evolutionary biology — Posted on 2024-07-15

2926 Origin and stepwise improvement of vertebrate lungs

Li, Y.; Hu, M.; Zhang, Z.; Wu, B.; Zheng, J.; Zhang, F.; Hao, J.; Xue, T.; Li, Z.; Zhu, C.; Zhao, L.; Xu, W.; Xin, P.; Feng, C.; Wang, W.; Zhao, Y.; Qiu, Q.; wang, K.

10.1101/2024.07.14.603411 — evolutionary biology — Posted on 2024-07-15

2927 Taking a BREATH (Bayesian Reconstruction and Evolutionary Analysis of Transmission Histories) to simultaneously infer phylogenetic and transmission trees for partially sampled outbreaks

Colijn, C.; Hall, M. D.; Bouckaert, R.

10.1101/2024.07.11.603095 — evolutionary biology — Posted on 2024-07-15

2928 Varying importance of postzygotic isolation in polyploid speciation? A survey of the triploid block strength, its causal mechanisms, and evolutionary consequences

Salony, S.; Clo, J.; Kolar, F.; Lafon Placette, C.

10.1101/2024.07.13.603373 — evolutionary biology — Posted on 2024-07-15

2929 In search for multifunctional lncRNAs

Iyengar, B. R.

10.1101/2024.07.11.603032 — evolutionary biology — Posted on 2024-07-15

2930 Membrane potential as master regulator of cellular mechano-transduction

Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.

10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-15

2931 Structure of the Femoral Chordotonal Organ in the Oleander hawkmoth, Daphnis nerii

Virdi, S.; Sane, S. P.

10.1101/2024.07.10.602854 — neuroscience — Posted on 2024-07-15

2932 Force Reserve Predicts Compensation in Reaching Movement with Induced Shoulder Strength Deficit

Faity, G.; Barradas, V. R.; Schweighofer, N.; Mottet, D.

10.1101/2024.03.28.587142 — neuroscience — Posted on 2024-07-15

2933 Soma-germ contact across the basement membrane in the ovary

Chikami, Y.; Yahata, K.

10.1101/2024.07.10.602885 — zoology — Posted on 2024-07-15

2934 The interplay of uncertainty, relevance and learning influences auditory categorization

Sheth, J.; Collina, J.; Piasini, E.; Kording, K. P.; Cohen, Y.; Geffen, M. N.

10.1101/2022.12.01.518777 — neuroscience — Posted on 2024-07-15

2935 Agrobacterium-mediated Cuscuta campestris transformation as a tool for understanding plant-plant interactions

Adhikari, S.; Mudalige, A.; Phillips, L.; Lee, H.; Bernal, V.; Gruszewski, H.; Westwood, J.; Park, S.-Y.

10.1101/2024.02.23.581736 — plant biology — Posted on 2024-07-15

2936 A tubulin-binding protein that preferentially binds to GDP-tubulin and promotes GTP exchange

Yon, W. J.; Ha, T.; Zheng, Y.; Pedersen, R. T.

10.1101/2023.05.09.539990 — biochemistry — Posted on 2024-07-15

2937 Spaceflight causes strain-dependent gene expression changes associated with lipid and extracellular matrix dysregulation in the mouse kidney in vivo

Finch, R. H.; Vitry, G.; Siew, K.; Walsh, S. B.; Beheshti, A.; Hardiman, G.; da Silveira, W. A.

10.1101/2024.03.13.584781 — genomics — Posted on 2024-07-15

2938 Onsager's relations and Ecology

Choi, J. S.; Hansell, R. I. C.

10.1101/2023.11.28.569100 — ecology — Posted on 2024-07-15

2939 Measles virus co-opts epithelial-to-mesenchymal transition and live cell extrusion to exit human airway epithelia

Sinn, P. L.; Hippee, C. E.; Durnell, L. A.; Kaufman, J.; Murray, E.; Singh, B. K.

10.1101/2024.07.12.603350 — microbiology — Posted on 2024-07-15

2940 Distinct Excitability Properties of Cardiac Calbindin Neurons: Identifying a Unique Neuronal Population

Lizot, G.; Bescond, J.; De Koninck, Y.; Chahine, M.; Bois, P.; Faivre, J.-F.; Chatelier, A.

10.1101/2024.05.31.596786 — physiology — Posted on 2024-07-15

2941 A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus

Reveyaz, N.; Schneeweiss, U.; Heise, O.; Gerhardt, B.; Gui, A. M.; Kaufmann, L. V.; Alfken, J.; Reichmann, J.; Salditt, T.; Hildebrandt, T. B.; Brecht, M.

10.1101/2023.11.15.567239 — neuroscience — Posted on 2024-07-15

2942 Predicting Theory of Mind in children from the infant connectome

Schueler, C.; Berger, P.; Grosse Wiesmann, C.

10.1101/2024.05.22.595346 — neuroscience — Posted on 2024-07-15

2943 Developmental dynamics of the prefrontal cortical SST and PV interneuron networks: Insights from the monkey highlight human-specific features

Hosseini Fin, N. S.; Yip, A.; Teo, L.; Homman-Ludiye, J.; Bourne, J. A.

10.1101/2024.07.10.602904 — neuroscience — Posted on 2024-07-15

2944 Molecular chaperone BiP controls activity of the ER stress sensor Ire1 through interactions with its oligomers

Dawes, S.; Hurst, N.; Grey, G.; Wieteska, L.; Wright, N. V.; Manfield, I. W.; Hussain, M. H.; Kalverda, A. P.; Lewandowski, J. R.; Chen, B.; Zhuravleva, A.

10.1101/2024.02.16.579620 — biophysics — Posted on 2024-07-15

2945 Developmental stage determines the realized energy landscape for a flight specialist

Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J. S.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.

10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-07-15

2946 The regulatory grammar of human promoters uncovered by MPRA-trained deep learning

Barbadilla-Martinez, L.; Klaassen, N. H.; Franceschini-Santos, V. H.; Breda, J.; Hernandez-Quiles, M.; van Lieshout, T.; Urzua Traslavina, C. G.; Yücel, H.; Boi, M. C. L.; Hermana-Garcia-Agullo, C.; Gregoricchio, S.; Zwart, W. H.; Voest, E.; Franke, L.; Vermeulen, M.; de Ridder, J.; van Steensel, B.

10.1101/2024.07.09.602649 — genetics — Posted on 2024-07-15

2947 Optimization of gene knockout approaches and practical solutions to sgRNA selection challenges in hPSCs with inducible Cas9 system

Ni, J.; Gong, J.; Ran, Y.; Bai, R.; Huang, P.; Zhou, M.; Zheng, Z.; You, Y.; Lan, F.; Liu, X.

10.1101/2024.07.09.602644 — cell biology — Posted on 2024-07-15

2948 Redefining hematopoietic progenitor cells and reforming the hierarchy of hematopoiesis

Chen, L.; Sun, Q.; Li, G.; Huang, Q.; Chen, S.; Fu, Y.; Yue, Y.

10.1101/2023.01.27.524347 — cell biology — Posted on 2024-07-15

2949 Cortical sensory aging is layer-specific

Liu, P.; Doehler, J.; Henschke, J. U.; Northall, A.; Serian, A.; Loaiza-Carvajal, L. C.; Budinger, E.; Schwarzkopf, D. S.; Speck, O.; Pakan, J. M. P.; Kuehn, E.

10.1101/2023.12.01.567841 — neuroscience — Posted on 2024-07-15

2950 Characteristics of vicarious touch reports in a general population

Smit, S.; Crossley, M. J.; Zopf, R.; Rich, A.

10.1101/2024.01.30.577948 — neuroscience — Posted on 2024-07-15

2951 Evolving patterns of extreme publishing behavior across science

Ioannidis, J.; Collins, T. A.; Baas, J.

10.1101/2023.11.23.568476 — scientific communication and education — Posted on 2024-07-15

2952 Longitudinal Multi-Tensor Analysis of Neocortical Microstructure in an Animal Model of Cortical Dysplasia

Villasenor, P. J.; Luna-Munguia, H.; Ramirez-Manzanares, A.; Coronado-Leija, R.; Concha, L.

10.1101/2024.07.09.602800 — neuroscience — Posted on 2024-07-15

2953 Emergence of cellular nematic order is a conserved feature of gastrulation in animal embryos

Li, X.; Huebner, R. J.; Williams, M. L. K.; Sawyer, J.; Peifer, M.; Wallingford, J. B.; Thirumalai, D.

10.1101/2024.07.11.603175 — developmental biology — Posted on 2024-07-15

2954 Muscle and intestine innexins with muscle Deg/Enac channels promote muscle coordination and embryo elongation

LLENSE, F.; FERRARO, T.; YANG, X.; SONG, H.; LABOUESSE, M.

10.1101/2024.07.12.603207 — developmental biology — Posted on 2024-07-15

2955 The Abelson kinase and the Nedd4-family E3 ligases co-regulate Notch trafficking to limit signaling

Miranda-Alban, J.; Sanchez-Luege, N.; Valbuena, F. M.; Rangel, C.; Rebay, I.

10.1101/2024.07.12.603272 — developmental biology — Posted on 2024-07-15

2956 Unremodeled plasma membrane GPI-anchored proteins trigger aberrant clathrin-mediated endocytosis

Chen, L.; Banfield, D. K.

10.1101/2024.07.12.603263 — cell biology — Posted on 2024-07-15

2957 Induction and characterisation of Abeta and tau pathology in AppNL-F/NL-F mice following inoculation with Alzheimer's disease brain homogenate

Purro, S. A.; Farmer, M.; Quarterman, E.; Ravey, J.; Thomas, D. X.; Noble, E.; Turnbull, C.; Linehan, J.; Nazari, T.; Brandner, S.; Farrow, M. A.; Walsh, D. M.; Collinge, J.

10.1101/2024.07.11.602448 — neuroscience — Posted on 2024-07-15

2958 The tubule-sheet continuum model links the pattern of nuclear envelope assembly to nuclear envelope integrity

Arun, S.; Zhao, G.

10.1101/2024.07.14.603427 — cell biology — Posted on 2024-07-15

2959 Nitration of a ribosomal pentapeptide generates a noncanonical precursor for nonribosomal peptide synthesis

Padva, L.; Zimmer, L.; Gullick, J.; Zhao, Y.; Sasi, V. M.; Schittenhelm, R. B.; Jackson, C. J.; Cryle, M. J.; Cruesemann, M.

10.1101/2024.07.12.603347 — biochemistry — Posted on 2024-07-14

2960 Interchromosomal segmental duplication drives translocation and loss of P. falciparum histidine-rich protein 3

Hathaway, N. J.; Kim, I. E.; Young, N. W.; Hui, S. T.; Crudale, R.; Giesbrecht, D.; Liang, E. Y.; Nixon, C. P.; Juliano, J. J.; Parr, J. B.; Bailey, J. A.

10.1101/2022.12.07.519189 — genomics — Posted on 2024-07-14

2961 Neutral speciation in realistic populations

Nelson, E. D.

10.1101/2024.01.10.575124 — ecology — Posted on 2024-07-14

2962 Apoptotic caspases cleave DRP1 to promote mitochondrial fusion and anti-viral immune responses

Fang, Y.; Guan, Z.; Zhu, X.; Guan, Z.; Li, S.; Peng, K.

10.1101/2024.07.13.603409 — microbiology — Posted on 2024-07-14

2963 Functional analysis of cyclic diguanylate-modulating proteins in Vibrio fischeri

Isenberg, R. Y.; Holschbach, C. S.; Gao, J.; Mandel, M. J.

10.1101/2023.07.24.550417 — microbiology — Posted on 2024-07-14

2964 Evaluate the efficiency of Mr BMT in macrophage replacement of peripheral organs

Du, J.; Yang, B.; He, Y.; Rao, Y.

10.1101/2024.06.22.600056 — immunology — Posted on 2024-07-14

2965 Directed fMRI-based Functional Connectivity Estimation using Physics-Informed Neural Networks

Sotero, R.; Sanchez-Bornot, J.

10.1101/2024.07.09.602748 — neuroscience — Posted on 2024-07-14

2966 Partial FAM19A5 Deficiency in Mice Leads to Disrupted Spine Maturation, Hyperactivity and Altered Fear Response

SHAHAPAL, A.; Park, S.; Yoo, S.; Seong, J. Y.

10.1101/2024.04.29.591582 — neuroscience — Posted on 2024-07-14

2967 Recording γ-secretase activity in living mouse brains

Hou, S. S.; Ikegawa, Y.; Kwon, Y.; Wieckiewicz, N.; Houser, M. C. Q.; Lundin, B.; Bacskai, B. J.; Berezovska, O.; Maesako, M.

10.1101/2024.01.31.578105 — neuroscience — Posted on 2024-07-14

2968 FAM19A5 Deficiency Mitigates the Aβ Plaque Burden and Improves Cognition in Mouse Models of Alzheimer's Disease

Park, S.; Shahapal, A.; Yoo, S.; Hwang, J.-I.; Seong, J. Y.

10.1101/2024.05.08.593243 — neuroscience — Posted on 2024-07-14

2969 NF-κB Epigenetic Attractor Landscape Drives Breast Cancer Heterogeneity

Lopes, F. J. P.; Pires, B. R. B.; Lima, A. A. B.; Binato, R.; Abdelhay, E.

10.1101/2024.07.10.602798 — systems biology — Posted on 2024-07-14

2970 Programmable promoter editing for precise control of transgene expression

Kabaria, S. R.; Bae, Y.; Ehmann, M. E.; Beitz, A. M.; Lende-Dorn, B. A.; Peterman, E. L.; Love, K. S.; Ploessl, D. S.; Galloway, K. E.

10.1101/2024.06.19.599813 — synthetic biology — Posted on 2024-07-14

2971 Single-cell resolved differentiation of pre-Kranz anatomy in maize leaf primordia

Yi, J.; Su, H.; Tian, S.; Sedelnikova, O.; Chen, Y.; Zhao, C.; Yang, J.; Zhang, Y.; Zhu, X.-G.; Langdale, J.; Wang, J.; Wang, P.

10.1101/2024.07.10.602848 — plant biology — Posted on 2024-07-14

2972 A Receptor Like Cytoplasmic Kinase evolved in Aeschynomene legumes to mediate Nod-independent rhizobial symbiosis

Horta Araujo, N.; Landry, D.; Quilbe, J.; Pervent, M.; Klopp, C.; Nouwen, N.; Racoupeau, M.; Gully, D.; Rios, M.; Brottier, L.; Pichereaux, C.; Gressent, F.; Chaintreuil, C.; Gough, C.; Giraud, E.; Lefebvre, B.; ARRIGHI, J.-F.

10.1101/2024.07.10.602847 — plant biology — Posted on 2024-07-14

2973 MAGA: a contig assembler with correctness guarantee

Salmela, L.

10.1101/2024.07.10.602853 — bioinformatics — Posted on 2024-07-14

2974 DMRIntTk: integrating different DMR sets based on density peak clustering

Zhang, W.; Jie, W.; Cui, W.; Duan, G.; Zou, Y.; Peng, X.

10.1101/2024.07.10.602837 — bioinformatics — Posted on 2024-07-14

2975 The regulatory potential of transposable elements in maize

Bubb, K. L.; Hamm, M. O.; Min, J. K.; Ramirez-Corona, B.; Mueth, N. A.; Ranchalis, J.; Vollger, M. R.; Trapnell, C.; Cuperus, J. T.; Queitsch, C.; Stergachis, A. B.

10.1101/2024.07.10.602892 — genomics — Posted on 2024-07-14

2976 Increasing intraspecific plant chemical diversity at plot and plant level affects herbivorous, predatory, and pollinating arthropod communities

Ojeda-Prieto, L.; Moreno, E. L.; Heinen, R.; Weisser, W. W.

10.1101/2024.07.10.602874 — ecology — Posted on 2024-07-14

2977 Inclusive, Exclusive and Hierarchical Atlas of NFATc1+/PDGFR-alpha+ Cells in Dental and Periodontal Mesenchyme

Yang, X.; Han, C.; Yu, C.; Zhou, B.; Ye, L.; Li, F.; Yu, F.

10.1101/2024.07.10.602887 — developmental biology — Posted on 2024-07-14

2978 VIRAL METAGENOMIC SURVEY OF CASPIAN SEALS

Karamendin, K.; Goodman, S. J.; Kasymbekov, Y.; Kumar, M.; Nuralibekov, S.; Kydyrmanov, A.

10.1101/2024.07.14.603418 — microbiology — Posted on 2024-07-14

2979 A new pathway in central metabolism mediates nutrient control of development and antibiotic production by Streptomyces

Li, C.; Urem, M.; Kotsogianni, I.; Lau, j.; Elsayed, S. S.; Martin, N. I.; McNae, I.; Voskamp, P.; Mayer, C.; Rigali, S.; Pannu, N.; Abrahams, J.-P.; Schada von Borzyskowski, L.; van Wezel, G. P.

10.1101/2024.07.14.603434 — microbiology — Posted on 2024-07-14

2980 Integrative deep immune profiling of the elderly reveals systems-level signatures of aging, sex, smoking, and clinical traits

Riemann, L.; Gutierrez, R.; Odak, I.; Barros-Martins, J.; Roesner, L. M.; Leon Lara, X.; Falk, C.; Schulz, T. F.; Hansen, G.; Werfel, T.; Foerster, R.

10.1101/2024.07.10.602828 — immunology — Posted on 2024-07-14

2981 Spurious correlations in surface-based functional brain imaging

Jeganathan, J.; Koussis, N. C.; Paton, B.; L, S. M.; Zalesky, A.; Breakspear, M.

10.1101/2024.07.09.602799 — neuroscience — Posted on 2024-07-14

2982 Connectome predictive modeling of trait mindfulness

Treves, I. N.; Kucyi, A.; Park, M.; Kral, T. R. A.; Goldberg, S. B.; Davidson, R. J.; Rosenkranz, M.; Whitfield-Gabrieli, S.; Gabrieli, J. D. E.

10.1101/2024.07.09.602725 — neuroscience — Posted on 2024-07-14

2983 AgRP1 modulates breeding season-dependent feeding behavior in female medaka

Tagui, Y.; Takeda, S.; Waida, H.; Kitahara, S.; Kimura, T.; Kanda, S.; Oka, Y.; Hayashi, Y.; Umatani, C.

10.1101/2024.07.10.602830 — neuroscience — Posted on 2024-07-14

2984 Lectin Microarray Analysis of Salivary Gland Glycoproteins from the Arboviral Vector Aedes aegypti and the Malaria Vector Anopheles stephensi

Ramasamy, R.; Chen, X.; Zhang, J.; Sivabalakrishnan, K.; Arthiyan, S.; Surendran, S. N.

10.1101/2024.07.10.602877 — zoology — Posted on 2024-07-14

2985 Trypanosome infection rate and blood-feeding patterns of tsetse fly in an area with a recent human African trypanosomiasis outbreak in Southwest Ethiopia

Desta, T.; Kore, K.; Eligo, N.; Tamiru, G.; Tesfaye, Y.; Lindtjorn, B.; Massebo, F.

10.1101/2024.07.10.602836 — zoology — Posted on 2024-07-14

2986 Preimaginal development of Aedes aegypti in brackish water produces adult mosquitoes with thicker cuticles and greater insecticide resistance

Ramasamy, R.; Sivabalakrishnan, K.; Hemphill, A.; Karunaratne, P.; Naguleswaran, A.; Roditi, I.; Surendran, S. N.

10.1101/2024.07.10.602862 — zoology — Posted on 2024-07-14

2987 Strawberry COP9 signalosome FvCSN5 regulates plant development and fruit ripening by facilitating polyamine oxidase FvPAO5 degradation to control polyamine and H2O2 homeostasis

Huang, Y.; Gao, J. H.; Wang, Q.; Ji, G. M.; Li, W.; Shen, Y.; Guo, J.; Gao, F.

10.1101/2024.07.10.602942 — plant biology — Posted on 2024-07-14

2988 FUSION: A web-based application for in-depth exploration of multi-omics data with brightfield histology

Border, S.; Melo Ferreira, R.; Lucarelli, N.; Kumar, S.; Paul, A.; Manthey, D.; Barisoni, L.; Strekalova, Y.; Ray, J.; Cheng, Y.-H.; Rosenberg, A. Z.; Tomaszewski, J. E.; Mimar, S.; Hodgin, J. B.; HuBMAP consortium, ; El-Achkar, T. M.; Jain, S.; Eadon, M. T.; Sarder, P.

10.1101/2024.07.09.602778 — pathology — Posted on 2024-07-14

2989 Acetate drives ovarian cancer quiescence via ACSS2-mediated acetyl-CoA production

Sharrow, A. C.; Megill, E.; Chen, A. J.; Farooqi, A.; McGonigal, S.; Hempel, N. W.; Snyder, N. W.; Buckanovich, R. J.; Aird, K. M.

10.1101/2024.07.12.603313 — cancer biology — Posted on 2024-07-14

2990 Quantifying "just-right" APC inactivation for colorectal cancer initiation

Brunet Guasch, M.; Feeley, N.; Soriano, I.; Thorn, S. B.; Tomlinson, I.; Nicholson, M.; Antal, T.

10.1101/2024.07.10.602868 — cancer biology — Posted on 2024-07-14

2991 Discovery and Repurposing of Multi-Target Senolytics through Structure-Based Virtual Screening

Olacoaga, S.; Königsberg, M.; Cortes-Benitez, F.; Perez-Villanueva, J.; Lopez-Diazguerrero, N. E.

10.1101/2024.07.09.602796 — bioinformatics — Posted on 2024-07-14

2992 The S-lignin O-demethylase SyoA: Structural insights into a new class of heme peroxygenase enzymes

Harlington, A. C.; Das, T.; Shearwin, K. E.; Bell, S. G.; Whelan, F.

10.1101/2024.07.14.603228 — biochemistry — Posted on 2024-07-14

2993 Benchmarking and Optimization of Methods for the Detection of Identity-By-Descent in High-Recombining Plasmodium falciparum

Guo, B.; Takala-Harrison, S.; O'Connor, T. D.

10.1101/2024.05.04.592538 — evolutionary biology — Posted on 2024-07-14

2994 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex

Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.

10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-14

2995 Orthology inference at scale with FastOMA

Majidian, S.; Nevers, Y.; Yazdizadeh Kharrazi, A.; Warwick Vesztrocy, A.; Pascarelli, S.; Moi, D.; Glover, N.; Altenhoff, A. M.; Dessimoz, C.

10.1101/2024.01.29.577392 — bioinformatics — Posted on 2024-07-14

2996 Accelerating de novo SINE annotation in plant and animal genomes

Liao, H.; Sun, Y.; Ou, S.

10.1101/2024.03.01.582874 — bioinformatics — Posted on 2024-07-14

2997 An explanation for the sister repulsion phenomenon in Patterson's f-statistics

Atag, G.; Waldman, S.; Carmi, S.; Somel, M.

10.1101/2024.02.17.580509 — genetics — Posted on 2024-07-14

2998 TPM4 condensates glycolytic enzymes to fuel actin reorganization under hyperosmotic stress

Yang, W.; Wang, Y.; Liu, G.; Wang, Y.; Wu, C.

10.1101/2024.07.09.602822 — cell biology — Posted on 2024-07-14

2999 Rapid evolution of gene expression patterns in flowering plants

Schuster, C.; Gabel, A.; Drost, H.-G.; Grosse, I.; Leyser, O.; Meyerowitz, E. M.

10.1101/2024.07.08.602577 — plant biology — Posted on 2024-07-14

3000 Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy

Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.; Enderlein, J.

10.1101/2023.08.23.554438 — biophysics — Posted on 2024-07-14

3001 Distinct representation of locomotive action affordances in human behavior, brains and deep neural networks

Bartnik, C. G.; Sartzetaki, C.; Puigseslloses Sanchez, A.; Molenkamp, E.; Bommer, S.; Vuksic, N.; Groen, I. I. A.

10.1101/2024.05.15.594298 — neuroscience — Posted on 2024-07-14

3002 Evaluation of a Real-time Plasmid Transmission Detection Pipeline

Scherff, N.; Rothgänger, J.; Weniger, T.; Mellmann, A.; Harmsen, D.

10.1101/2024.07.09.602722 — bioinformatics — Posted on 2024-07-14

3003 E2VD: a unified evolution-driven framework for virus variation drivers prediction

Nie, Z.; Liu, X.; Chen, J.; Wang, Z.; Liu, Y.; Si, H.; Dong, T.; Xu, F.; Song, G.; Wang, Y.; Zhou, P.; Gao, W.; Tian, Y.

10.1101/2023.11.27.568815 — bioinformatics — Posted on 2024-07-14

3004 A tubulin-binding protein that preferentially binds to GDP-tubulin and promotes GTP exchange

Yon, W. J.; Ha, T.; Zheng, Y.; Pedersen, R. T.

10.1101/2023.05.09.539990 — biochemistry — Posted on 2024-07-14

3005 Buffering effects of nonspecifically DNA-bound RNA polymerases in bacteria

Yan, Y.; Li, T.; Lin, J.

10.1101/2023.11.04.565427 — microbiology — Posted on 2024-07-14

3006 Does pre-speech auditory modulation reflect processes related to feedback monitoring or speech movement planning?

Li, J. J.; Daliri, A.; Kim, K. S.; Max, L.

10.1101/2024.07.13.603344 — neuroscience — Posted on 2024-07-13

3007 Enhancing the accuracy of genome-scale metabolic models with kinetic information

Lazaro Ibanez, J.; Wongprommoon, A.; Julvez, J.; Oliver, S. G.

10.1101/2024.07.11.597182 — systems biology — Posted on 2024-07-14

3008 Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice

Lian, P.; Kovynev, A.; Wang, L.; Pronk, A. C. M.; Verhoeven, A.; Giera, M.; Thijssen, S.; Martinez Tellez, B.; Kooijman, S.; Rensen, P. C.; Timmerman, H.; Wichers, H. J.; Henricks, P. A. J.; Folkerts, G.; Schonke, M.; Braber, S.

10.1101/2024.07.10.602866 — physiology — Posted on 2024-07-14

3009 Expansion of mammary intraepithelial lymphocytes and intestinal inputs shape T cell dynamics in lactogenesis

Jaquish, A.; Phung, E.; Gong, X.; Baldominos, P.; Galvan-Pena, S.; Bursulaya, I.; Magill, I.; ImmgenT consortium, ; Bertrand, K.; Chambers, C.; Agudo, J.; Mathis, D.; Benoist, C.; Ramanan, D.

10.1101/2024.07.09.602739 — immunology — Posted on 2024-07-13

3010 Synchronous theta networks characterize successful memory retrieval

Rao, A. M.; Kahana, M. J.

10.1101/2024.07.12.603286 — neuroscience — Posted on 2024-07-13

3011 Neuron synchronization analyzed through spatial-temporal attention

Yang, H.; KC, P.; Chen, P.; Lei, H.; Sponberg, S.; Tarokh, V.; Riffell, J.

10.1101/2024.07.10.602834 — neuroscience — Posted on 2024-07-13

3012 From histology to macroscale function in the human amygdala

Auer, H.; Cabalo, D. G.; Rodriguez-Cruces, R.; Benkarim, O.; Paquola, C.; Dekraker, J.; Wang, Y.; Valk, S. L.; Bernhardt, B.; Royer, J.

10.1101/2024.07.09.602743 — neuroscience — Posted on 2024-07-13

3013 Fundamental frequency predominantly drives talker differences in auditory brainstem responses to continuous speech

Polonenko, M. J.; Maddox, R. K.

10.1101/2024.07.12.603125 — neuroscience — Posted on 2024-07-13

3014 Enhancing Retrieval Capacity of the Predictive Brain through Dorsolateral Prefrontal Cortex Intervention

Szucs-Bencze, L.; Vekony, T.; Pesthy, O.; Kocsis, K.; Kincses, Z. T.; Szabo, N.; Nemeth, D.

10.1101/2024.07.10.602829 — neuroscience — Posted on 2024-07-13

3015 Post-weaning social isolation alters sociability in a sex-specific manner

Myers, T.; Birmingham, E. A.; Rhoads, B. T.; McGrath, A. G.; Miles, N. A.; Schuldt, C. B.; Briand, L. A.

10.1101/2024.07.11.603129 — neuroscience — Posted on 2024-07-13

3016 An extreme mutational hotspot in nlpD depends on transcriptional induction of rpoS

Farr, A. D.; Vasileiou, C.; Lind, P. A.; Rainey, P. B.

10.1101/2024.07.11.603030 — evolutionary biology — Posted on 2024-07-13

3017 A fast and robust gene knockout method for Salpingoeca rosetta clarifies the genetics of choanoflagellate multicellular development

Combredet, C.; Brunet, T.

10.1101/2024.07.13.603360 — evolutionary biology — Posted on 2024-07-13

3018 Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis

Pessenda, G.; Ferreira, T. R.; Paun, A.; Kabat, J.; Amaral, E. P.; Kamenyeva, O.; Gazzinelli-Guimaraes, P. H.; Perera, S. R.; Ganesan, S.; Lee, S. H.; Sacks, D. L.

10.1101/2024.07.09.602717 — immunology — Posted on 2024-07-13

3019 HDAC4 Inhibits NMDA Receptor-Mediated Stimulation of Neurogranin Expression

de Andres, R.; Martinez-Blanco, E.; Diez-Guerra, F. J.

10.1101/2024.07.09.602724 — neuroscience — Posted on 2024-07-13

3020 Engineering Microglial Cells to Promote Spinal Cord Injury Recovery

Zhou, Q.; Liu, J.; Fang, Q.; Zhang, C.; Liu, W.; Sun, Y.

10.1101/2024.07.09.602797 — neuroscience — Posted on 2024-07-13

3021 Msh3 and Pms1 Set Neuronal CAG-repeat Migration Rate to Drive Selective Striatal and Cortical Pathogenesis in HD Mice

10.1101/2024.07.09.602815 — neuroscience — Posted on 2024-07-13

3022 Sex-related differences in vascular remodeling of sodium overloaded normotensive mice

Silva, J. C. d. S.; Viegas, K. A. d. S.; Lima, R. S. d.; Lima, C. T.; Peron, N. N.; Silva, M. B. d.; Irigoyen, M. C.; Lacchini, S.

10.1101/2024.07.09.602349 — physiology — Posted on 2024-07-13

3023 Accurate isoform quantification by joint short- and long-read RNA-sequencing

Apostolides, M.; Choi, B.; Navickas, A.; Saberi, A.; Soto, L. M.; Goodarzi, H.; Najafabadi, H. S.

10.1101/2024.07.11.603067 — bioinformatics — Posted on 2024-07-13

3024 Silicon Nitride Induces Osteoconduction Via Activated Mitochondrial Oxidative Phosphorylation and Neovascularization

Gonzales, W. D.; Khade, R.; Kondo, T.; Arimoto, S.; Inagaki, T.; Hokugo, A.; Kaczor-Urbanowicz, K. E.; McEntire, B.; Bock, R. M.; Ogawa, T.; Pezzotti, G.; Nishimura, I.

10.1101/2024.07.09.602787 — bioengineering — Posted on 2024-07-13

3025 How to choose the optimal RNA-Seq library characteristics for alternative splicing analysis

Ladwig, A.; Klostermann, M.; Zarnack, K.

10.1101/2024.07.11.603071 — genomics — Posted on 2024-07-13

3026 Pre-Assembly NGS Correction of ONT Reads Achieves HiFi-Level Assembly Quality

Mozheiko, E.; Yi, H.; Lu, A.; Kong, H.; Hou, Y.; Zhou, Y.; Gao, H.

10.1101/2024.07.12.603260 — genomics — Posted on 2024-07-13

3027 Detecting latent gene-environment interaction when analyzing binary traits

Zhang, Z.; Lawless, J. F.; Paterson, A. D.; Sun, L.

10.1101/2024.07.10.602954 — genetics — Posted on 2024-07-13

3028 Prophage-encoded Hm-oscar gene recapitulates Wolbachia-induced male killing in the tea tortrix moth Homona magnanima

Arai, H.; Katsuma, S.; Matsuda-Imai, N.; Lin, S.-R.; Inoue, M. N.; Kageyama, D.

10.1101/2024.07.12.603262 — evolutionary biology — Posted on 2024-07-13

3029 Ventral Morphology and Ecological Implications of Cindarella eucalla (Artiopoda, Xandarellida) from Chengjiang Biota, China

Zhang, M.; Liu, Y.; Mai, H.; Schmidt, M.; Hou, X.

10.1101/2024.07.10.602865 — evolutionary biology — Posted on 2024-07-13

3030 Strength of enemy release from parasitoids is context-dependent in the invasive African Fig Fly, Zaprionus indianus

Walsh-Antzak, C. R.; Erickson, P. A.

10.1101/2024.07.09.602257 — ecology — Posted on 2024-07-13

3031 METTL3 shapes m6A epitranscriptomic landscape for successful human placentation

Kumar, R. P.; Kumar, R.; Ganguly, A.; Ghosh, A.; Ray, S.; Islam, M. R.; Saha, A.; Roy, N.; Dasgupta, P.; Knowles, T.; Niloy, A. J.; Marsh, C.; Paul, S.

10.1101/2024.07.12.603294 — developmental biology — Posted on 2024-07-13

3032 Multisite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox withdiverse applications in vertebrate model systems.

Gillespie, W.; Zhang, Y.; Ruiz, O. E.; Cerda, J.; Ortiz-Guzman, J.; Turner, W. D.; Largoza, G.; Sherman, M.; Mosser, L. E.; Fujimoto, E.; Chien, C.-B.; Kwan, K. M.; Arenkiel, B. R.; Devine, W. P.; Wythe, J.

10.1101/2024.07.13.603267 — molecular biology — Posted on 2024-07-13

3033 Mitigating sTNF/TNFR1 activation on VGluT2+ spinal cord interneurons improves immune function after mid-thoracic spinal cord injury

Martynyuk, T.; Ricard, J.; Bracchi-Ricard, V.; Price, S.; McGrath, J.; Dougherty, K.; Tom, V.; Bethea, J. R.

10.1101/2024.07.09.602690 — neuroscience — Posted on 2024-07-13

3034 Sulfonylurea receptor coupled conductances alter the performance of two central pattern generating circuits in Cancer borealis

Kedia, S.; Awal, N. M.; Seddon, J.; Marder, E.

10.1101/2024.07.09.602760 — neuroscience — Posted on 2024-07-13

3035 Antiviral immunity within neural stem cells distinguishes viral strain differences in forebrain organoids

Vazquez, C.; Negatu, S. G.; Bannerman, C. D.; Sriram, S.; Ming, G.-L.; Jurado, K. A.

10.1101/2024.07.09.602767 — immunology — Posted on 2024-07-13

3036 Ongoing genome doubling promotes evolvability and immune dysregulation in ovarian cancer

10.1101/2024.07.11.602772 — cancer biology — Posted on 2024-07-13

3037 Scalable Antigen-Antibody Binding Affinity Landscape: A Case Study with ENHERTU

Li, W.

10.1101/2024.07.12.603351 — biophysics — Posted on 2024-07-13

3038 Pymportx: Facilitating Next-Generation Transcriptomics Analysis in Python

Pena Gonzalez, P.; Lozano-Paredes, D.; Rojo, J. L.; Bote-Curiel, L.; Sanchez-Arevalo Lobo, V. J.

10.1101/2024.07.12.598873 — bioinformatics — Posted on 2024-07-13

3039 Enhanced sensitivity of TAPscan v4 enables comprehensive analysis of streptophyte transcription factor evolution

Petroll, R.; Varshney, D.; Hiltemann, S.; Finke, H.; Schreiber, M.; de Vries, J.; Rensing, S. A.

10.1101/2024.07.13.602682 — bioinformatics — Posted on 2024-07-13

3040 A New Era in Missense Variant Analysis: Statistical Insights and the Introduction of VAMPP-Score for Pathogenicity Assessment

Aydin, E.; Ergun, B.; Akgun-Dogan, O.; Alanay, Y.; Hatirnaz Ng, O.; Ozdemir, O.

10.1101/2024.07.11.602867 — genomics — Posted on 2024-07-13

3041 Ribosomal DNA arrays are the most H-DNA rich element in the human genome

Chantzi, N.; Patsakis, M.; Nayak, A.; Montgomery, A.; Mouratidis, I.; Georgakopoulos Soares, I.

10.1101/2024.07.12.602585 — genomics — Posted on 2024-07-13

3042 Structural variants underlie parallel adaptation following global invasion

Battlay, P.; Hendrickson, B. T.; Mendez-Reneau, J. I.; Santangelo, J. S.; Albano, L. J.; Wilson, J.; Caizergues, A. E.; King, N.; Puentes, A.; Tudoran, A.; Violle, C.; Vasseur, F.; Patterson, C. M.; Foster, M. J.; Stamps, C.; Innes, S. G.; Allio, R.; Angeoletto, F.; Anstett, D. N.; Anstett, J.; Bucharova, A.; Comerford, M. S.; David, S.; Falahati Anbaran, M.; Godsoe, W.; Gonzalez-Lagos, C.; Gundel, P. E.; Hood, G. R.; Karousou, R.; Lampei, C.; Lara, C.; Lazaro-Lobo, A.; Leandro, D.; Merritt, T. J.; Mitchell, N.; Mohammadi Bazargani, M.; Moles, A.; Murua, M.; Paule, J.; Pfeiffer, V.; Raeymaeker

10.1101/2024.07.09.602765 — evolutionary biology — Posted on 2024-07-13

3043 PP1 PNUTS binds the restrictor and dephosphorylates RNA pol II CTD Ser5 to stimulate transcription termination

Bentley, D.; Treisman, R.; Erickson, B.; Fong, N.; Hansen, K.; Sheridan, R. M.; Larson, K.; Saviola, A.; Fedoryshchak, R.; Mouilleron, S.

10.1101/2024.07.12.603302 — molecular biology — Posted on 2024-07-13

3044 Bioenergetic stress potentiates antimicrobial resistance and persistence

Li, B.; Srivastava, S.; Shaikh, M.; Mereddy, G.; Garcia, M. R.; Shah, A.; Ofori-Anyinam, N.; Chu, T.-Y.; Cheney, N.; Yang, J. H.

10.1101/2024.07.12.603336 — microbiology — Posted on 2024-07-13

3045 LRRK2 kinase activity restricts NRF2-dependent mitochondrial protection in microglia

Weindel, C. G.; Ellzey, L. M.; Coleman, A. K.; Patrick, K. L.; Watson, R. O.

10.1101/2024.07.09.602769 — immunology — Posted on 2024-07-13

3046 IL-21 Shapes the B Cell Response in a Context-Dependent Manner

Kim, Y.; Manara, F.; Grassmann, S.; Belcheva, K.; Reyes, K.; Kim, H.; Downs-Canner, S.; Yewdell, W. T.; Sun, J. C.; Chaudhuri, J.

10.1101/2024.07.13.600808 — immunology — Posted on 2024-07-13

3047 Influence of asymmetric microchannels in the structure and function of engineered neuronal circuits

Mateus, J. C.; Melo, P.; Aroso, M.; Charlot, B.; Aguiar, P.

10.1101/2024.07.09.602729 — neuroscience — Posted on 2024-07-13

3048 Chronic β3 adrenergic agonist treatment improves brain microvascular endothelial function and cognition in aged mice

Natarajan, D.; Ekambaram, S.; Tarantini, S.; Yelahanka Nagaraja, R.; Yabluchanskiy, A.; Hendrik, A.; Awasthi, V.; Subramanian, M.; Csiszar, A.; Balasubramanian, P.

10.1101/2024.07.09.602747 — neuroscience — Posted on 2024-07-13

3049 Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking

Cooper, C.; Parthier, D.; Sibille, J.; Tukker, J. J.; Tritsch, N. X.; Schmitz, D.

10.1101/2024.07.09.602643 — neuroscience — Posted on 2024-07-13

3050 PyINETA: Open-source platform for INADEQUATE-JRES integration in NMR metabolomics

Taujale, R.; Uchimiya, M.; Clendinen, C. S.; Borges, R. M.; Turck, C. W.; Edison, A. S.

10.1101/2024.07.10.601875 — systems biology — Posted on 2024-07-13

3051 The penetration ring is a novel infection structure formed by the penetration peg for invading plant cell membrane in rice blast fungus

Fang, W.; Zai, X.; Chen, J.; Abubakar, Y. S.; Wu, Q.; Fang, Z.; Huang, X.; Gan, X.; Ebbole, D. J.; Wang, Z.; Zheng, W.

10.1101/2024.07.11.603048 — pathology — Posted on 2024-07-13

3052 Lipid Organization by the Caveolin-1 Complex

Liebl, K.; Voth, G. A.

10.1101/2024.07.10.602986 — biophysics — Posted on 2024-07-13

3053 Kidney mRNA-protein expression correlation: What can we learn from the Human Protein Atlas?

Acoba, D.; Reznichenko, A.

10.1101/2024.07.12.601822 — bioinformatics — Posted on 2024-07-13

3054 STRPsearch: fast detection of structured tandem repeat proteins

Mozaffari, S.; Arrias, P. N.; Clementel, D.; Piovesan, D.; Ferrari, C.; Tosatto, S. C. E.; Monzon, A. M.

10.1101/2024.07.10.602726 — bioinformatics — Posted on 2024-07-13

3055 Pseudo-perplexity in One Fell Swoop for Protein Fitness Estimation

Kantroo, P.; Wagner, G.; Machta, B.

10.1101/2024.07.09.602754 — bioinformatics — Posted on 2024-07-13

3056 Where the patterns are: repetition-aware compression for colored de Bruijn graphs

Campanelli, A.; Pibiri, G. E.; Fan, J.; Patro, R.

10.1101/2024.07.09.602727 — bioinformatics — Posted on 2024-07-13

3057 The Powered Simplest Walking Model Modifies the Rate of Recovery Definition

Hosseini-Yazdi, S.-S.

10.1101/2024.07.09.602732 — bioengineering — Posted on 2024-07-13

3058 Developing a Soft Micropatterned Substrate to Enhance Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs)

Maaref, Y.; Jannati, S.; Akbari, M.; Chiao, M.; Tibbits, G. F.

10.1101/2024.07.12.599409 — bioengineering — Posted on 2024-07-13

3059 Genome report: Genome sequence of the tuliptree scale insect, Toumeyella liriodendri (Gmelin)

Mongue, A. J.; Markee, A.; Grebler, E.; Liesenfelt, T.; Powell, E. C.

10.1101/2024.07.09.602735 — genomics — Posted on 2024-07-13

3060 Genomic insights into red squirrels in Scotland reveals loss of heterozygosity associated with extreme founder effects

Marr, M. M.; Humble, E.; Lurz, P. W. W.; Wilson, L. A.; Milne, E.; Beckmann, K. M.; Schoenebeck, J.; Fung, U.-Y.-Y.; Kitchener, A. C.; Kortland, K.; Edwards, C.; Ogden, R.

10.1101/2024.07.10.602565 — genomics — Posted on 2024-07-13

3061 An updated DNA barcoding tool for Aloe vera and related CITES-regulated species

Woudstra, Y.; Rees, P.; Rakotoarisoa, S. E.; Roensted, N.; Howard, C.; Grace, O. M.

10.1101/2024.07.09.602761 — genomics — Posted on 2024-07-13

3062 Transposable element accumulation drives genome size increase in Hylesia metabus (Lepidoptera: Saturniidae), an urticating moth species from South America

Perrier, C.; Allio, R.; Legeai, F.; Gautier, M.; Beneluz, F.; Marande, W.; Theron, A.; Rodde, N.; Herrera, M.; Saune, L.; Parrinello, H.; McClure, M.; Arias, M.

10.1101/2024.07.11.602864 — genomics — Posted on 2024-07-13

3063 Cryptic diversity shapes coral symbioses, physiology, and response to thermal challenge

Aichelman, H. E.; Benson, B. E.; Gomez-Campo, K.; Martinez-Rugerio, M. I.; Fifer, J. E.; Tsang, L.; Hughes, A. M.; Bove, C. B.; Nieves, O. C.; Pereslete, A. M.; Stanizzi, D.; Kriefall, N. G.; Baumann, J. H.; Rippe, J. P.; Gondola, P.; Castillo, K. D.; Davies, S. W.

10.1101/2024.07.09.602709 — evolutionary biology — Posted on 2024-07-13

3064 Ideal efficacy photoswitches for TRPC4/5 channels harness high potency for spatiotemporally-resolved control of TRPC function in live tissues

Müller, M.; Niemeyer, K.; Ojha, N. K.; Porav, S. A.; Vinayagam, D.; Urban, N.; Büchau, F.; Oleinikov, K.; Makke, M.; Bauer, C. C.; Johnson, A. V.; Muench, S. P.; Zufall, F.; Bruns, D.; Schwarz, Y.; Raunser, S.; Leinders-Zufall, T.; Bon, R. S.; Schaefer, M.; Thorn-Seshold, O.

10.1101/2024.07.12.602451 — cell biology — Posted on 2024-07-13

3065 Follicle stimulating hormone receptor expression in human pancreas and effects on insulin secretion: A translational study

Aydin, B. K.; Incedal Nilsson, C.; Chowdhury, A.; Wen, Q.; Cerenius, S. Y.; Stenlid, R.; Morwald, K.; Ciba, I.; Manell, H.; Weghuber, D.; Forslund, A.; Idevall-Hagren, O.; Bergsten, P.

10.1101/2024.07.12.603223 — cell biology — Posted on 2024-07-13

3066 An INS-1 beta-cell proteome highlights the role of fatty acid biosynthesis in glucose-stimulated insulin secretion

Stremmel, N.; Lemke, O.; Textoris-Taube, K.; Ludwig, D.; Muelleder, M.; Muenzner, J.; Ralser, M.

10.1101/2024.07.12.603204 — cell biology — Posted on 2024-07-13

3067 Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b

Baker, A. L.; Arruda, B.; Palmer, M. V.; Boggiatto, P.; Sarlo Davila, K.; Buckley, A.; Ciacci Zanella, G.; Snyder, C. A.; Anderson, T. K.; Hutter, C.; Nguyen, T.-Q.; Markin, A.; Lantz, K.; Posey, E. A.; Torchetti, M. K.; Robbe-Austerman, S.; Magstadt, D. R.; Gorden, P. J.

10.1101/2024.07.12.603337 — microbiology — Posted on 2024-07-13

3068 Endemism shapes viral ecology and evolution in globally distributed hydrothermal vent ecosystems

Langwig, M. V.; Koester, F.; Martin, C.; Zhou, Z.; Joye, S. B.; Reysenbach, A.-L.; Anantharaman, K.

10.1101/2024.07.12.603268 — microbiology — Posted on 2024-07-13

3069 Measles virus co-opts epithelial-to-mesenchymal transition and live cell extrusion to exit human airway epithelia

Sinn, P. L.; Hippee, C. E.; Durnell, L. A.; Kaufman, J.; Murray, E.; Singh, B. K. K.

10.1101/2024.07.12.603350 — microbiology — Posted on 2024-07-13

3070 Neuronal GPCR NMUR-1 regulates energy homeostasis in response to pathogen infection

Wibisono, P.; Liu, Y.; Roberts, K. P.; Baluya, D.; Sun, J.

10.1101/2024.07.09.602733 — immunology — Posted on 2024-07-13

3071 Influenza-induced alveolar macrophages protect against death by malaria-associated acute lung injury (MA-ALI)

Reed, J. S.; Nayan, R.; Deckers, M.; Evavold, B. D.; Lamb, T. J.

10.1101/2024.07.12.601219 — immunology — Posted on 2024-07-13

3072 Identification and Description of Emotions by Current Large Language Models

Patel, S. C.; Fan, J.

10.1101/2023.07.17.549421 — neuroscience — Posted on 2024-07-13

3073 On the validity of electric brain signal predictions based on population firing rates

Ness, T. V.; Tetzlaff, T.; Einevoll, G. T.; Dahmen, D.

10.1101/2024.07.10.602833 — neuroscience — Posted on 2024-07-13

3074 "Micro-offline gains" convey no benefit for motor skill learning

Das, A.; Karagiorgis, A.; Diedrichsen, J.; Stenner, M.-P.; Azanon, E.

10.1101/2024.07.11.602795 — neuroscience — Posted on 2024-07-13

3075 EGFR meets hATG8s - Biophysical and structural insights supporting a unique role of GABARAP during receptor trafficking

Üffing, A.; Weiergräber, O. H.; Schwarten, M.; Hoffmann, S.; Willbold, D.

10.1101/2024.07.10.602929 — biophysics — Posted on 2024-07-13

3076 From in vitro to in silico: a pipeline for generating virtual tissue simulations from real image data

Nuernberg, E.; Vitacolonna, M.; Bruch, R.; Reischl, M.; Rudolf, R.; Sauer, S.

10.1101/2024.07.12.603259 — biophysics — Posted on 2024-07-13

3077 Are cell length and volume interchangeable in cell cycle analysis?

Kar, P.; Amir, A.

10.1101/2024.07.09.602793 — biophysics — Posted on 2024-07-13

3078 Advancing membrane-associated protein docking with improved sampling and scoring in Rosetta

Samnata, R.; Harmalkar, A.; Prathima, P.; Gray, J. J.

10.1101/2024.07.09.602802 — biophysics — Posted on 2024-07-13

3079 REAL-TIME VISUALIZATION OF SPLICEOSOME ASSEMBLY REVEALS BASIC PRINCIPLES OF SPLICE SITE SELECTION

Donovan, B. T.; Wang, B.; Garcia, G. R.; Mount, S. M.; Larson, D. R.

10.1101/2024.07.12.603320 — biophysics — Posted on 2024-07-13

3080 OpenTn5: Open-Source Resource for Robust and Scalable Tn5 Transposase Purification and Characterization

Soroczynski, J.; Anderson, L. J.; Yeung, J. L.; Rendleman, J. M.; Oren, D. A.; Konishi, H. A.; Risca, V. I.

10.1101/2024.07.11.602973 — genomics — Posted on 2024-07-13

3081 Resolving the chromatin impact of mosaic variants with targeted Fiber-seq

Bohaczuk, S. C.; Amador, Z. J.; Li, C.; Mallory, B. J.; Swanson, E. G.; Ranchalis, J.; Vollger, M. R.; Munson, K. M.; Walsh, T.; Hamm, M. O.; Mao, Y.; Lieber, A.; Stergachis, A. B.

10.1101/2024.07.09.602608 — genomics — Posted on 2024-07-13

3082 Optimization of gene knockout approaches and practical solutions to sgRNA selection challenges in hPSCs with inducible Cas9 system

Liu, X.; Lan, F.; Ni, J.; Gong, J.; Ran, Y.; Bai, R.; Huang, P.; Zhou, M.; Zheng, Z.; You, Y.

10.1101/2024.07.09.602644 — cell biology — Posted on 2024-07-13

3083 Robustness with Limited Specificity of Telomere Binding Proteins Underlies Telomere Evolution in Nematoda

Song, H.; Kim, S. H.; Lim, D. S.; Choi, H.-J.; Lee, J.

10.1101/2024.07.11.603171 — cell biology — Posted on 2024-07-13

3084 Search for candidate substances from the spiny red gurnard Chelidonichthys spinosus, as novel food additives that color cultivated meat red

Shimada, E.; Tsuruwaka, Y.

10.1101/2024.07.11.601406 — cell biology — Posted on 2024-07-13

3085 Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface

Broich, L.; Wullenkord, H.; Osman, M. K.; Fu, Y.; Reuther, P.; Broenstrup, M.; Sieben, C.

10.1101/2024.07.13.603385 — microbiology — Posted on 2024-07-13

3086 Pseudomonas aeruginosa infection increases palmitoyl carnitine release by host-derived extracellular vesicles

Ayilam Ramachandran, R.; Baniasadi, H.; Robertson, D. M.

10.1101/2024.07.13.603378 — microbiology — Posted on 2024-07-13

3087 Natural phasic inhibition of dopamine neurons signals cognitive rigidity

Burwell, S. C. V.; Yan, H.; Lim, S. S. X.; Shields, B. C.; TADROSS, M. R.

10.1101/2024.05.09.593320 — neuroscience — Posted on 2024-07-13

3088 CODANIN-1 sequesters ASF1 by using a histone H3 mimic helix to regulate histone supply

Jeong, T.-K.; Frater, R. C. M.; Groth, A.; Song, J.-J.

10.1101/2024.07.10.602876 — biophysics — Posted on 2024-07-13

3089 From resting state to inactivation: the dynamic journey of the inactivation peptide in Shaker Kv channels

Pandey, R.; Kalstrup, T.; Blunck, R.

10.1101/2024.07.10.602816 — biophysics — Posted on 2024-07-13

3090 Dynamics and Activation of Membrane-Bound B Cell Receptor Assembly

Do, H. N.; Zhao, M.; Alam, S. M.; Gnanakaran, S.

10.1101/2024.07.10.602784 — biophysics — Posted on 2024-07-13

3091 E. coli do not count single molecules

Mattingly, H. H.; Kamino, K.; Kottou, R.; Ong, J.; Emonet, T.; Machta, B. B.

10.1101/2024.07.09.602750 — biophysics — Posted on 2024-07-13

3092 Stabilization Mechanism of Initiator Transfer RNA in the Small Ribosomal Subunit from Coarse-Grained Molecular Simulations

Mori, Y.; Tanaka, S.

10.1101/2024.07.12.603193 — biophysics — Posted on 2024-07-13

3093 Long-term single-molecule tracking in living cells using weak-affinity protein labeling

Catapano, C.; Dietz, M. S.; Kompa, J.; Jang, S.; Freund, P.; Johnsson, K.; Heilemann, M.

10.1101/2024.07.11.603077 — biophysics — Posted on 2024-07-13

3094 Simplest Model of Nervous System. IV. General Solution

Sinitskiy, A.

10.1101/2024.07.10.603010 — biophysics — Posted on 2024-07-13

3095 A conformational fingerprint for amyloidogenic light chains.

Paissoni, C.; Puri, S.; BROGGINI, L.; Sriramoju, M. K.; Maritan, M.; Russo, R.; Speranzini, V.; Ballabio, F.; Nuvolone, M.; Merlini, G.; Palladini, G.; Hsu, S.-T. D.; Ricagno, S.; Camilloni, C.

10.1101/2024.07.12.603200 — biophysics — Posted on 2024-07-13

3096 Modified Chlorophyll Pigment at ChlD1 Tunes Photosystem II Beyond the Red-Light Limit

Allgower, F.; Sirohiwal, A.; Gamiz-Hernandez, A. P.; Poverlein, M. C.; Fantuzzi, A.; Rutherford, A. W.; Kaila, V. R. I.

10.1101/2024.07.13.603357 — biophysics — Posted on 2024-07-13

3097 DNA supercoiling enhances DNA condensation by ParB proteins

Martin Gonzalez, A.; Tisma, M.; Analikwu, B. T.; Barth, A.; Janissen, R.; Antar, H.; Kemps, G.; Gruber, S.; Dekker, C.

10.1101/2024.07.11.603076 — biophysics — Posted on 2024-07-13

3098 Unveiling the role of yeast cytochrome c isoforms in the assembly of mitochondrial supercomplexes and the control of respiratory chain rate

Guerra-Castellano, A.; Aneas, M.; Tamargo-Azpilicueta, J.; Marquez, I.; Olloqui-Sariego, J. L.; Calvente, J. J.; De la Rosa, M. A.; Diaz Moreno, I.

10.1101/2024.07.13.603375 — biophysics — Posted on 2024-07-13

3099 Rep structures can be tuned by ionicity via metastable intermediates in the absence of DNA

Howard, J. A. L.; Ambrose, B.; Abdelhamid, M. A. S.; Alevropoulos-Borrill, A.; Ejaz, A.; Dresser, L.; Dienerowitz, M.; Quinn, S. D.; Squires, A. H.; Noy, A.; Craggs, T. D.; Leake, M. C.

10.1101/2024.07.12.603287 — biophysics — Posted on 2024-07-13

3100 A novel mechanism of microbial attachment: the flagellar pump of Giardia lamblia

Picou, T. J.; Luo, H.; Polackwich, R.; Gabilondo, B. B.; McAllister, R. G.; Gagnon, D. A.; Powers, T. R.; Elmendorf, H. G.; Urbach, J.

10.1101/2024.07.09.602685 — biophysics — Posted on 2024-07-13

3101 How cells align to structured collagen fibrils: A hybrid cellular Potts and molecular dynamics model with dynamic mechanosensitive focal adhesions.

Keijzer, K. A.; Tsingos, E.; Merks, R. M. H.

10.1101/2024.07.10.602851 — biophysics — Posted on 2024-07-13

3102 Nitration of a ribosomal pentapeptide generates a noncanonical precursor for nonribosomal peptide synthesis

Padva, L.; Zimmer, L.; Gullick, J.; Zhao, Y.; Sasi, V. M.; Schittenhelm, R. B.; Jackson, C. J.; Cryle, M. J.; Crueseman, M.

10.1101/2024.07.12.603347 — biochemistry — Posted on 2024-07-13

3103 Legacy effects of extreme events

Brueggemeier-Singh, D.; Vos, M.

10.1101/2024.07.09.602699 — ecology — Posted on 2024-07-13

3104 Monovalent Pseudo-Natural Product Degraders Supercharge the Native Degradation of IDO1 by KLHDC3

Hennes, E.; Lucas, B.; Scholes, N. S.; Cheng, X.-f.; Scott, D. C.; Bischoff, M.; Reich, K.; Gasper, R.; Lucas, M.; Xu, T. T.; Pulvermacher, L.-M.; Doetsch, L.; Imrichova, H.; Brause, A.; Naredla, K. R.; Sievers, S.; Kumar, K.; Janning, P.; Gersch, M.; Murray, P. J.; Schulmann, B. A.; Winter, G. E.; Ziegler, S.; Waldmann, H.

10.1101/2024.07.10.602857 — cell biology — Posted on 2024-07-13

3105 A dynamic redox switch turns TRC40 into a chaperone protecting human cells against ATP-depleting, oxidative stress

Dempsey, B.; Dubrall, R.; Chan, O.; Lapacz, K. J.; Riemer, J.; Jakob, U.; Ulrich, K.

10.1101/2024.07.10.602939 — cell biology — Posted on 2024-07-13

3106 Impact of physical activity on physical performance, mitochondrial bioenergetics, ROS production and calcium handling across the human adult lifespan

Cefis, M.; Marcangeli, V.; Hammad, R.; Granet, J.; Leduc-Gaudet, J.-P.; Gaudreau, P.; Trumpff, C.; Huang, Q.; Picard, M.; Aubertin-Leheudre, M.; Belanger, M.; Morais, J. A.; Gouspillou, G.

10.1101/2024.07.09.602758 — cell biology — Posted on 2024-07-13

3107 Phase Separation of Actin-Binding Protein TPM4 Fuels Glycolysis under Hyperosmotic Stress

Yang, W.; Wang, Y.; Liu, G.; Wang, Y.; Wu, C.

10.1101/2024.07.09.602822 — cell biology — Posted on 2024-07-13

3108 Defining a Muscle Stem Cell matrisome signature: from transcriptome data to extracellular matrix niche topology.

Guillon, E.; Bacar, H.; Sasaki, T.; Mourikis, P.; Ruggiero, F.

10.1101/2024.07.10.602878 — cell biology — Posted on 2024-07-13

3109 Maturation of Human Intestinal Epithelial Cell Layers Fortifies the Apical Surface against Salmonella Attack

van Rijn, J. M.; Lopes, A. C. C.; Ceylan, M.; Eriksson, J.; Bergholtz, A.; Ntokaki, A.; Hammar, R.; Sundbom, M.; Skogar, M.; Graf, W.; Webb, D.-L.; Hellström, P. M.; Artursson, P.; Pelaseyed, T.; Di Martino, M. L.; Sellin, M. E.

10.1101/2024.07.11.603014 — cell biology — Posted on 2024-07-13

3110 Cryo-ET reveals the in situ architecture of the polar tube invasion apparatus from microsporidian parasites

Usmani, M.; Coudray, N.; Riggi, M.; Raghu, R.; Ramchandani, H.; Bobe, D.; Kopylov, M.; Zhong, E. D.; Iwasa, J. H.; Ekiert, D. C.; Bhabha, G.

10.1101/2024.07.13.603322 — microbiology — Posted on 2024-07-13

3111 Immunisation of chickens with inactivated and/or infectious H9N2 avian influenza virus leads to differential immune B cell repertoire development

Dascalu, S.; Sealy, J. E.; Sadeyen, J.-R.; Flammer, P. G.; Fiddaman, S.; Preston, S. G.; Dixon, R. J.; Bonsall, M. B.; Smith, A. L.; Iqbal, M.

10.1101/2024.07.09.602583 — immunology — Posted on 2024-07-13

3112 AGEing of Collagen: The Effects of Glycation on Collagen's Stability, Mechanics and Assembly

Sloseris, D.; Forde, N. R.

10.1101/2024.07.09.602794 — biophysics — Posted on 2024-07-13

3113 eIF1 and eIF5 dynamically control translation start site fidelity

Grosely, R.; Alvarado, C.; Ivanov, I. P.; Nicholson, O. B.; Puglisi, J. D.; Dever, T. E.; Lapointe, C. P.

10.1101/2024.07.10.602410 — biophysics — Posted on 2024-07-13

3114 Regulation of Kv1.2 redox-sensitive gating by the transmembrane lectin LMAN2

Lamothe, S. M.; Das, D.; Wong, A. A.; Hao, Y.; Maguire, A. D.; Kerr, B. J.; Baronas, V. A.; Kurata, H. T.

10.1101/2024.07.09.602766 — biophysics — Posted on 2024-07-13

3115 scGFT: single-cell RNA-seq data augmentation using generative Fourier transformer

Nouri, N.

10.1101/2024.07.09.602768 — bioinformatics — Posted on 2024-07-13

3116 Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells

Sytsma, B. J.; Allain, V.; Bourke, S.; Faizee, F.; Fathi, M.; Berdeaux, R.; Ferreira, L. M. R.; Brewer, J. W.; Li, L.; Pan, F. L.; Rothrock, A. G.; Nyberg, W. A.; Li, Z.; Wilson, L. H.; Eyquem, J.; Pawell, R. S.

10.1101/2024.06.25.600671 — bioengineering — Posted on 2024-07-13

3117 A draft Arab pangenome reference

Nassir, N.; Almarri, M.; Kumail, M.; Mohamed, N.; Balan, B.; Hanif, S.; AlObathani, M.; Jamlalail, B.; Elsokary, H.; Kondaramage, D.; Shiyas, S.; Kosaji, N.; Satsangi, D.; Abdelmotagali, M.; AbouTayoun, A.; Ahmed, O.; Youssef, D.; Al Suwaidi, H.; Albanna, A.; Duplessis, S.; Khansaheb, H.; Alsheikh-Ali, A.; Uddin, M.

10.1101/2024.07.09.602638 — genomics — Posted on 2024-07-13

3118 Changes in the functional diversity and abundance of ectomycorrhizal fungi are decoupled from water uptake patterns in European beech forests

Rodriguez-Una, A.; Moreno-Mateos, D.; Matesanz, S.; Wingate, L.; Barbeta, A.; Porras, J.; Gimeno, T. E.

10.1101/2024.07.09.602659 — ecology — Posted on 2024-07-13

3119 Moderate Cold Stress Enhance Drought Resistance through CCA1 via -an ABA- independent Pathway

Yang, X.; Liu, Y.; Jia, Z.-C.; Li, M.; Hou, X.-X.; Hou, S.-Q.; Shi, X.-L.; Chen, M.-X.; Liu, Y.-G.

10.1101/2024.07.09.602734 — cell biology — Posted on 2024-07-13

3120 Spleen Tyrosine Kinase (SYK) negatively regulates ITAM-mediated human NK cell signaling and CD19-CAR NK cell efficacy

Millan, A. J.; Allain, V.; Nayak, I.; Aguilar, O. A.; Arakawa- Hoyt, J. S.; Ureno, G.; Rothrock, A. G.; Shemesh, A.; Eyquem, J.; Das, J.; Lanier, L. L.

10.1101/2024.07.09.602676 — immunology — Posted on 2024-07-13

3121 Interleukin-33 from oligodendrocytes sustains effector differentiation of tissue-resident CD8+ T cells and is a druggable target in CNS autoimmune disease

Fonta, N.; Page, N.; Klimek, B.; Piccinno, M.; Di Liberto, G.; Lemeille, S.; Kreutzfeldt, M.; Kastner, A. L.; Ertuna, Y. I.; Vincenti, I.; Wagner, I.; Pinschewer, D. D.; Merkler, D.

10.1101/2024.07.09.602661 — immunology — Posted on 2024-07-13

3122 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex

Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.

10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-13

3123 Curvature coding in early visual system revealed by scale variance during adaptation to flashing circles

Nisar, I.; Elder, J. H.

10.1101/2023.02.11.528121 — neuroscience — Posted on 2024-07-13

3124 A systematic evaluation of dynamic functional connectivity methods using simulation data

Yuan, B.; Yang, J.; Guo, X.; Gao, X.; Hu, Z.; Li, J.; Liu, J.; Wang, Y.; Qu, Z.; Li, W.; Li, Z.; Li, W.; Huang, Y.; Chen, J.; Wen, H.; Li, J.; Liu, D.-Q.; Xie, H.

10.1101/2024.07.09.600728 — neuroscience — Posted on 2024-07-13

3125 Sensing cellular growth rate facilitates its robust optimal adaptation to changing conditions

Planque, R.; Hulshof, J.; Bruggeman, F.

10.1101/2024.07.09.602663 — systems biology — Posted on 2024-07-13

3126 Temperature-dependent polar lignification of a seed coat suberin layer promoting dormancy in Arabidopsis thaliana

Hyvärinen, L.; Fuchs, C.; Utz-Pugin, A.; Gully, K.; Megies, C.; Holbein, J.; Iwasaki, M.; Demonsais, L.; Capitao, M. B.; Barberon, M.; Franke, R.; Nawrath, C.; Loubery, S.; Lopez-Molina, L.

10.1101/2024.07.09.602674 — plant biology — Posted on 2024-07-13

3127 Cytokinin acts as a systemic signal coordinating reproductive effort in Arabidopsis

Volkava, D.; Bukovcakova, S. V.; Mikulkova, P.; Pecinkova, J.; Skalak, J.; Hejatko, J.; Riha, K.

10.1101/2024.07.09.602718 — plant biology — Posted on 2024-07-13

3128 HERMES: Holographic Equivariant neuRal network model for Mutational Effect and Stability prediction

Visani, G. M.; Pun, M. N.; Galvin, W.; Daniel, E.; Borisiak, K.; Wagura, U.; Nourmohammad, A.

10.1101/2024.07.09.602403 — bioinformatics — Posted on 2024-07-13

3129 3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma

Lee, V. K.; Tejero, R.; Silvia, N.; Sattiraju, A.; Ramakrishnan, A.; Shen, L.; Wojcinski, A.; Kesari, S.; Friedel, R. H.; Zou, H.; Dai, G.

10.1101/2024.07.09.601756 — bioengineering — Posted on 2024-07-13

3130 Colony demographics shape nest construction in ants

Rajendran, H.; Weinberger, R.; Fonio, E.; Feinerman, O.

10.1101/2024.07.09.602713 — animal behavior and cognition — Posted on 2024-07-13

3131 The regulatory grammar of human promoters uncovered by MPRA-trained deep learning

Barbadilla-Martinez, L.; Klaassen, N. H.; Fransceschini-Santos, V.; Breda, J.; Hernandez-Quiles, M.; van Lieshout, T.; Urzua, C.; Yucel, H.; Boi, M. C. L.; Hermana-Garcia, C.; Gregoricchio, S.; Zwart, W. H.; Voest, E.; Franke, L.; Vermeulen, M.; de Ridder, J.; van Steensel, B.

10.1101/2024.07.09.602649 — genetics — Posted on 2024-07-13

3132 Roles of P-body factors in Candida albicans filamentation and stress response

Tosiano, M. A.; Lanni, F.; Mitchell, A. P.; McManus, J.

10.1101/2024.07.09.602714 — genetics — Posted on 2024-07-13

3133 Genetic architecture and adaptation of Ladakh highlanders of trans-Himalayas

Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.

10.1101/2024.02.05.579041 — genetics — Posted on 2024-07-13

3134 Tempo and mode of diversification of the red devil spiders (Araneae: Dysderidae) of the Canary Islands

Bellvert, A.; Pollock, L.; Kaliontzopoulou, A.; Arnedo, M. A.

10.1101/2024.07.09.601672 — evolutionary biology — Posted on 2024-07-13

3135 Predicting recoverability of collapsed food webs through perturbation and dimension reduction

Patnaik, S.; Baruah, G.

10.1101/2024.07.09.602684 — ecology — Posted on 2024-07-13

3136 Realisation threshold revisited: does the minimum tooth size scale with body size?

Christensen, M.; Laakkonen, J.; Jernvall, J.

10.1101/2024.07.09.602691 — developmental biology — Posted on 2024-07-13

3137 PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing

Rodriguez, T. C.; Yurkovetskiy, L.; Nagalekshmi, K.; Lam, C. H. O.; Jazbec, E.; Maitland, S. A.; Wolfe, S.; Sontheimer, E. J.; Luban, J.

10.1101/2024.07.12.603173 — microbiology — Posted on 2024-07-13

3138 Exploring For Gloss: The Role of Active Exploration in Visual Material Perception

Lin, L. P. Y.; Drewing, K.; Doerschner, K.

10.1101/2024.07.09.602662 — neuroscience — Posted on 2024-07-13

3139 Identification of whole-body reaching movement phenotypes in young and older active adults: an unsupervised machine learning approach

PFAFF, M.; CASTERAN, M.

10.1101/2024.07.09.600023 — neuroscience — Posted on 2024-07-13

3140 Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models

Power, S. K.; Venkatesan, S.; Qu, S.; McLaurin, J.; Lambe, E. K.

10.1101/2023.11.09.566499 — neuroscience — Posted on 2024-07-13

3141 Taming a behavioral monster: Resonant song recognition and the evolution of acoustic communication in crickets

Mann, W.; Erregger, B.; Hennig, R. M.; Clemens, J.

10.1101/2024.07.09.602660 — neuroscience — Posted on 2024-07-13

3142 Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits

Sanchiz-Calvo, M.; Coccia, E.; Cawthorne, C.; Parfitt, G.; Van Laere, K.; Torre-Muruzabal, T.; Cabezudo, D.; Tsafaras, G.; Cascalho, A.; Van Den Haute, C.; Vangheluwe, P.; Blanchard, J.; Bentea, E.; Baekelandt, V.

10.1101/2024.07.09.602700 — neuroscience — Posted on 2024-07-13

3143 Visual analysis of spatial transcriptomics data with RedeViz

Wang, D.; Ren, X.

10.1101/2024.07.09.602652 — bioinformatics — Posted on 2024-07-13

3144 Microglia-specific transduction via AAV11 armed with IBA1 promoter and miRNA-9 targeting sequences

Luo, N.; Lin, K.; Cai, Y.; Sui, X.; Zhang, Z.; Xing, J.; Liu, G.; Yuan, W.; Wang, J.; Xu, F.

10.1101/2024.07.09.602653 — neuroscience — Posted on 2024-07-13

3145 Advancements in Ligand-Based Virtual Screening through the Synergistic Integration of Graph Neural Networks and Expert-Crafted Descriptors

Liu, Y.; Moretti, R.; Wang, Y.; Dong, H.; Yan, B.; Bodenheimer, B.; Derr, T.; Meiler, J.

10.1101/2023.04.17.537185 — bioinformatics — Posted on 2024-07-13

3146 MIST: an interpretable and flexible deep learning framework for single-T cell transcriptome and receptor analysis

Lai, W.; Li, Y.; Luo, O. J.

10.1101/2024.07.05.602192 — bioinformatics — Posted on 2024-07-13

3147 ProLLM: Protein Chain-of-Thoughts Enhanced LLM for Protein-Protein Interaction Prediction

Jin, M.; Haochen, X.; Wang, Z.; Kang, B.; Ye, R.; Zhou, K.; Du, M.; Zhang, Y.

10.1101/2024.04.18.590025 — bioinformatics — Posted on 2024-07-13

3148 Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways

Nawrocka, W. I.; Cheng, S.; Hao, B.; Rosen, M. C.; Cortes, E.; Baltrusaitis, E. E.; Aziz, Z.; Kovacs, I. A.; Özkan, E.

10.1101/2024.07.08.602367 — biochemistry — Posted on 2024-07-13

3149 Sequencing, de novo assembly of Ludwigia plastomes, and comparative analysis within the Onagraceae family

Barloy-Hubler, F.; Le Gac, A.-L.; Boury, C.; Guichoux, E.; Barloy, D. H.

10.1101/2023.10.20.563230 — genomics — Posted on 2024-07-13

3150 Membrane potential as master regulator of cellular mechano-transduction

Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.

10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-13

3151 HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy

Galvez, N. M. S.; Cao, Y.; Nitido, A. D.; Deal, C. E.; Boutros, C. L.; MacDonald, S. W.; Soto Albrecht, Y. E.; Lam, E. C.; Sheehan, M. L.; Parsons, D.; Lin, A. Z.; Deymier, M. J.; Brady, J. M.; Moon, B.; Bullock, C. B.; Tanno, S.; Pegu, A.; Chen, X.; Liu, C.; Koup, R. A.; Mascola, J. R.; Vrbanac, V. D.; Lingwood, D.; Balazs, A. B.

10.1101/2024.07.11.603156 — microbiology — Posted on 2024-07-13

3152 Distinct pathway for evolution of enhanced receptor binding and cell entry in SARS-like bat coronaviruses

Tse, A. L.; Acreman, C. M.; Ricardo-Lax, I.; Berrigan, J.; Lasso, G.; Balogun, T.; Kearns, F. L.; Casalino, L.; McClain, G. L.; Chandran, A. M.; Lemeunier, C.; Amaro, R. E.; Rice, C. M.; Jangra, R. K.; McLellan, J. S.; Chandran, K.; Miller, E. H.

10.1101/2024.06.24.600393 — microbiology — Posted on 2024-07-13

3153 Ventral attention network connectivity is linked to cortical maturation and cognitive ability in childhood

Dong, H.; Zhang, X.-H.; Labache, L.; Zhang, S.; Ooi, L. Q. R.; Yeo, B. T. T.; Margulies, D. S.; Holmes, A.; Zuo, X.-N.

10.1101/2022.04.12.488101 — neuroscience — Posted on 2024-07-13

3154 Identifying and characterizing scene representations relevant for categorization behavior

Singer, J. J.; Karapetian, A.; Hebart, M. N.; Cichy, R. M.

10.1101/2023.08.17.553708 — neuroscience — Posted on 2024-07-13

3155 Guardian of Excitability: Multifaceted Role of Galanin in Whole Brain Excitability

Rieser, N. N.; Ronchetti, M.; Hotz, A. L.; Neuhauss, S. C.

10.1101/2024.04.05.588285 — neuroscience — Posted on 2024-07-13

3156 Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal phenotype for maximal T cell migration speeds

Alonso Matilla, R.; Provenzano, P.; Odde, D. J.

10.1101/2023.10.29.564655 — biophysics — Posted on 2024-07-13

3157 Transcriptomic analysis of meiotic genes during the mitosis-to-meiosis transition in Drosophila females

Valles, A. M.; Rubin, T.; Macaisne, N.; Dal Toe, L.; Molla-Herman, A.; Antoniewski, C.; Huynh, J.-R.

10.1101/2024.07.10.602987 — developmental biology — Posted on 2024-07-13

3158 Larva in the loop, a closed loop machine interface system for Danio rerio larvae

Jutoy, J.; Jung, E. E.

10.1101/2024.07.12.603215 — animal behavior and cognition — Posted on 2024-07-13

3159 A latitudinal gradient of reference genomes

Linck, E. B.; Cadena, D.

10.1101/2024.07.09.602657 — genomics — Posted on 2024-07-13

3160 Molecular profile, source and lineage restriction of stem cells in an annelid regeneration model

Stockinger, A. W.; Adelmann, L.; Fahrenberger, M.; Ruta, C.; Ozpolat, B. D.; Balavoine, G.; Raible, F.

10.1101/2024.07.09.602635 — developmental biology — Posted on 2024-07-13

3161 Unraveling the immunological roles of serum amyloid A3 in aortic immune cell subsets during atherosclerosis progression

Chou, T.-Y.; Ye, Y.-Z.; Lin, I.-J.; Lien, C.-J.; Yang, C.-H.; Chen, Y.-T.; Chao, P.-A.; Lin, J.-D.

10.1101/2024.07.09.602634 — immunology — Posted on 2024-07-13

3162 The neurovascular coupling response of the aged brain is brain-state dependent.

zhang, X.; Tao, L.; Nygaard, A. H.; Dong, Y.; Hong, X.; Goddard, C. M.; He, C.; Postnov, D. D.; Allodi, I.; Lauritzen, M.; Cai, C.

10.1101/2024.07.09.602636 — neuroscience — Posted on 2024-07-13

3163 Transient cortical Beta-frequency oscillations associated with contextual novelty in high density mouse EEG

Walsh, C.; Tait, L.; Garcia Garrido, M.; Brown, J. T.; Ridler, T.

10.1101/2024.07.09.602651 — neuroscience — Posted on 2024-07-13

3164 Multi-Model Machine Learning for Automated Identification of Rice Diseases Using Leaf Image Data

Tiwari, R.; Patel, J.; Khan, N. R. R.; Dadhich, A.; Jain, J. K. J.

10.1101/2024.07.09.602645 — plant biology — Posted on 2024-07-13

3165 Transient TELC and transmembrane potential in a laser flashed bacteriorhodopsin purple membrane open flat sheet

Lee, J.

10.1101/2024.07.09.602646 — biophysics — Posted on 2024-07-13

3166 Reproductive fluids enabling cryptic female choice of paternity do not induce concomitant gamete-mediated paternal effects in embryos of hybridizing salmonid fishes

Lantiegne, T. H.; Wagle, R.; Purchase, C. F.

10.1101/2024.07.09.602641 — evolutionary biology — Posted on 2024-07-13

3167 Synergistic reinforcement learning by cooperation of the cerebellum and basal ganglia

Yohida, T.; Sugino, H.; Yamamoto, H.; Tanno, S.; Tamura, M.; Igarashi, J.; Isomura, Y.; Hira, R.

10.1101/2024.07.12.603330 — neuroscience — Posted on 2024-07-13

3168 Exploring Anatomical Links Between the Crow's Nidopallium Caudolaterale and its Song System

Moll, F. W.; Kersten, Y.; Erdle, S.; Nieder, A.

10.1101/2024.07.12.603248 — neuroscience — Posted on 2024-07-13

3169 A conserved code for anatomy: Neurons throughout the brain embed robust signatures of their anatomical location into spike trains.

Tolossa, G. B.; Schneider, A. M.; Dyer, E. L.; Hengen, K. B.

10.1101/2024.07.11.603152 — neuroscience — Posted on 2024-07-13

3170 Inferring illness causes recruits the animacy semantic network

Hauptman, M.; Bedny, M.

10.1101/2024.07.10.602983 — neuroscience — Posted on 2024-07-13

3171 Females with autism spectrum disorders show stronger DNA methylation signatures than males in perinatal tissues

Mouat, J. S.; Krigbaum, N. Y.; Hakam, S.; Thrall, E.; Mellis, J.; Yasui, D. H.; Cirillo, P. M.; Ludena, Y.; Schmidt, R. J.; La Merrill, M. A.; Hertz-Picciotto, I.; Cohn, B. A.; LaSalle, J. M.

10.1101/2024.07.11.603098 — genomics — Posted on 2024-07-13

3172 Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling

Hanna, J.; Touahri, Y.; Pak, A.; Belfiore, L.; van Oosten, E.; David, L. A.; Han, S.; Ilnytskyy, Y.; Kovalchuk, I.; Kurrasch, D.; Okawa, S.; del Sol, A.; Screaton, R. A.; Aubert, I.; Schuurmans, C.

10.1101/2024.07.12.603298 — developmental biology — Posted on 2024-07-13

3173 Integrative LC-MS and GC-MS Metabolic Profiling Unveils Dynamic Changes during Barley Malting

Rani, H.; Whitcomb, S. J.

10.1101/2024.07.12.603295 — biochemistry — Posted on 2024-07-12

3174 Oxford Nanopore's 2024 sequencing technology for Listeria monocytogenes outbreak detection and source attribution: progress and clone-specific challenges

Biggel, M.; Cernela, N.; Horlbog, J. A.; Stephan, R.

10.1101/2024.07.12.603236 — genomics — Posted on 2024-07-12

3175 CUTS RNA Biosensor for the Real-Time Detection of TDP-43 Loss-of-Function

Xie, L.; Merjane, J.; Bergmann Munoz, C. A.; Xu, J.; Hurtle, B.; Donnelly, C. J.

10.1101/2024.07.12.603231 — molecular biology — Posted on 2024-07-12

3176 The impact of ERUPR on mitochondrial integrity mediated by PDK4

Mallick, P.; Maity, S.; Mondal, R.; Roy, T.; Chakrabarti, O.; Chakrabarti, S.

10.1101/2024.07.12.603217 — molecular biology — Posted on 2024-07-12

3177 Identification of stable reference genes for quantitative real-time PCR in human fibroblasts from lymph nodes and synovium

Rasouli, S.; van Ansenwoude, C.; Semmelink, J. F.; van Baarsen, L. G.; de Jong, T. A.

10.1101/2024.07.12.603332 — molecular biology — Posted on 2024-07-12

3178 ABCA1 and apoA-I dependent 12-hydroxyeicosatetraenoic acid efflux regulates macrophage inflammatory signaling

Harsch, B. A.; Borkowski, K.; Walker, R. E.; Pedersen, T. L.; Newman, J. W.; Shearer, G. C.

10.1101/2024.07.11.603001 — molecular biology — Posted on 2024-07-12

3179 Investigation of host plant contact with Diaphorina citri (Hemipreta: Psyllidae) by detecting D. citri-derived environmental DNA

Fujikawa, T.; Fujiwara, K.; Inoue, H.; Hatomi, H.; Hayashikawa, S.

10.1101/2024.07.12.603183 — molecular biology — Posted on 2024-07-12

3180 Differential amino acid usage leads to ubiquitous edge effect in proteomes across domains of life that can be explained by amino acid secondary structure propensities

Morimoto, J.; Pietras, Z.

10.1101/2024.07.12.599492 — molecular biology — Posted on 2024-07-12

3181 NanoTag - an IgG-free method for mapping DNA-protein interactions

Dimitriu, M. A.; Arzate-Mejia, R. G.; Steg, L. C.; Germain, P.-L.; Mansuy, I. M.

10.1101/2024.07.12.603224 — molecular biology — Posted on 2024-07-12

3182 The neonatal Fc receptor and DPP4 are human astrovirus receptors

Ingle, H.; Molleston, J. M.; Hall, P. D.; Bui, D.; Wang, L.; Foster, L.; Antia, A.; Ding, S.; Lee, S.; Fremont, D. H.; Baldridge, M. T.

10.1101/2024.07.12.603331 — microbiology — Posted on 2024-07-12

3183 Previously unknown regulatory role of extracellular RNA on bacterial directional migration

Tetz, V.; Kardava, K.; Vecherkovskaya, M.; Khodadadi-Jamayran, A.; Tsirigos, A.; Tetz, G.

10.1101/2024.07.11.603110 — microbiology — Posted on 2024-07-12

3184 An energy coupling factor transporter of Streptococcus sanguinis impacts antibiotic susceptibility as well as metal and membrane homeostasis

Rudzite, M.; O'Toole, G.

10.1101/2024.07.12.603315 — microbiology — Posted on 2024-07-12

3185 The bat Influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment

Osman, M. K.; Robert, J.; Broich, L.; Frank, D.; Grosse, R.; Schwemmle, M.; Wrobel, A.; Ciminski, K.; Sieben, C.; Reuther, P.

10.1101/2024.07.12.603249 — microbiology — Posted on 2024-07-12

3186 Depletion of skin bacteria by topical antibiotic treatment accelerates onset of Zika virus disease in mice.

Langendries, L.; Verwimp, S.; Jacobs, S.; Alpizar, Y. A.; Malengier-Devlies, B.; Abdelnabi, R.; Raes, J.; Callewaert, C.; Yshii, L.; Delang, L.

10.1101/2024.07.12.602934 — microbiology — Posted on 2024-07-12

3187 In vitro one-pot construction of influenza viral genomes for virus particle synthesis based on reverse genetics system

Tanaka, R.; Tamao, K.; Ono, M.; Yamayoshi, S.; Kawaoka, Y.; Su'etsugu, M.; Noji, H.; Tabata, K. V.

10.1101/2024.07.12.603202 — synthetic biology — Posted on 2024-07-12

3188 MDRepo - an open environment for data warehousing and knowledge discovery from molecular dynamics simulations

Roy, A.; Ward, E.; Choi, I.; Cosi, M.; Edgin, T.; Hughes, T. S.; Islam, M. S.; Khan, A. M.; Kolekar, A.; Rayl, M.; Robinson, I.; Sarando, P.; Skidmore, E.; Swetnam, T. L.; Wall, M.; Xu, Z.; Yung, M. L.; Merchant, N.; Wheeler, T. J.

10.1101/2024.07.11.602903 — biochemistry — Posted on 2024-07-12

3189 The mitochondrial Na+/Ca2+ exchanger NCLX is implied in the activation of hypoxia-inducible factors

Choya-Foces, C.; Hernansanz-Agustin, P.; Navarro, E.; Lopez, M. G.; Egea, J.; Martinez-Ruiz, A.

10.1101/2024.07.12.603081 — biochemistry — Posted on 2024-07-12

3190 The association between metabolite concentrations and wellbeing in adults

Azcona Granada, N.; Geijsen, A. J. M. R.; Pool, R.; Pelt, D. H. M.; Bartels, M.

10.1101/2024.07.12.603238 — biochemistry — Posted on 2024-07-12

3191 Post-proline cleaving enzymes also show specificity to reduced cysteine.

Kalaninova, Z.; Portasikova, J. M.; Jireckova, B.; Polak, M.; Novakova, J.; Kavan, D.; Novak, P.; Man, P.

10.1101/2024.07.12.603020 — biochemistry — Posted on 2024-07-12

3192 Resolving a neonatal intensive care unit outbreak of methicillin-resistant Staphylococcus aureus to the SNV level using Oxford Nanopore simplex reads and HERRO error correction

Bloomfield, M.; Bakker, S.; Burton, M.; Castro, M. L.; Dyet, K.; Eustace, A.; Hutton, S.; Macartney-Coxson, D.; Taylor, W.; White, R. T.

10.1101/2024.07.11.603154 — genomics — Posted on 2024-07-12

3193 DeepOrientation: Deep Orientation Estimation of Macromolecules in Cryo-electron tomography

Hajarolasvadi, N.; Baum, D.; Phelippeau, H.; Martinez-Sanchez, A.; Suau, P.-N.; Brandt, R.

10.1101/2024.07.12.603241 — molecular biology — Posted on 2024-07-12

3194 Surviving the Storm: Exploring the Role of Natural Transformation in Nutrition and DNA Repair of Stressed Deinococcus radiodurans

Sharma, D. K.; Soni, I.; Gupta, G. D.; Rajpurohit, Y. S.

10.1101/2024.07.11.603131 — molecular biology — Posted on 2024-07-12

3195 Cohesin-mediated 3D contacts tune enhancer-promoter regulation

Guckelberger, P.; Doughty, B. R.; Munson, G.; Rao, S. S. P.; Tan, Y.; Cai, X. S.; Fulco, C. P.; Nasser, J.; Mualim, K. S.; Bergman, D. T.; Ray, J.; Jagoda, E.; Munger, C. J.; Gschwind, A. R.; Sheth, M. U.; Tan, A. S.; Steinmetz, L. M.; Lander, E. S.; Meissner, A.; Lieberman Aiden, E.; Engreitz, J. M.

10.1101/2024.07.12.603288 — molecular biology — Posted on 2024-07-12

3196 Development of shuttle vector-based transformation systems for Chlamydia pecorum and Chlamydia caviae

Faessler, N.; Biggel, M.; Jelocnik, M.; Borel, N.; Marti, H.

10.1101/2024.07.11.603181 — microbiology — Posted on 2024-07-12

3197 A Kruppel-like factor establishes cellular heterogeneity during schistosome tegumental maintenance

Zhao, L.; Wendt, G. R.; Collins, J. J.

10.1101/2024.07.12.603265 — microbiology — Posted on 2024-07-12

3198 Global Phylogeography and Microdiversity of the Marine Diazotrophic Cyanobacteria Trichodesmium and UCYN-A

Nguyen, A.; Ustick, L. J.; Larkin, A. A.; Martiny, A. C.

10.1101/2024.07.12.603225 — microbiology — Posted on 2024-07-12

3199 Seasonal influenza A virus lineages exhibit divergent abilities to antagonize interferon induction and signaling

Rivera-Cardona, J.; Kakuturu, N.; Rowland, E. F.; Teo, Q. W.; Thayer, E. A.; Tan, T. J. C.; Sun, J.; Kieffer, C.; Wu, N. C.; Brooke, C. B.

10.1101/2024.07.11.603146 — microbiology — Posted on 2024-07-12

3200 PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing

Rodriguez, T. C.; Yurkovetskiy, L.; Nagalekshmi, K.; Lam, C. H. O.; Jazbec, E.; Maitland, S. A.; Wolfe, S.; Sontheimer, E. J.; Luban, J.

10.1101/2024.07.12.603173 — microbiology — Posted on 2024-07-12

3201 Mechanisms of life cycle simplification in African trypanosomes

Oldrieve, G. R.; Venter, F.; Cayla, M.; Verney, M.; Hebert, L.; Geerts, M.; Van Reet, N.; Matthews, K.

10.1101/2024.07.12.603250 — microbiology — Posted on 2024-07-12

3202 A rapid method to determine the genetic lineage of Escherichia coli using open reading frame composition in the shallow sequencing

Yagi, N.; Uechi, A.; Hirai, I.

10.1101/2024.07.11.601999 — microbiology — Posted on 2024-07-12

3203 RqcH supports survival in the absence of non-stop ribosome rescue factors

Callan, K.; Prince, C. R.; Feaga, H. A.

10.1101/2024.07.12.603306 — microbiology — Posted on 2024-07-12

3204 Cryptic cycling by electroactive bacterioplankton in Trout Bog Lake

Olmsted, C. N.; Gahler, M.; Roden, E.; Peterson, B.; Lazarcik, J.; Tran, P. Q.; Berg, M.; Bryant, D. A.; Qin, M.; McMahon, K.

10.1101/2024.07.11.603116 — microbiology — Posted on 2024-07-12

3205 HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy

Balazs, A. B.; Galvez, N. M. S.; Cao, Y.; Nitido, A. D.; Deal, C. E.; Boutros, C. L.; MacDonald, S. W.; Soto Albrecht, Y. E.; Lam, E. C.; Sheehan, M. L.; Parsons, D.; Lin, A. Z.; Deymier, M. J.; Brady, J. M.; Moon, B.; Bullock, C. B.; Tanno, S.; Pegu, A.; Chen, X.; Liu, C.; Koup, R. A.; Mascola, J. R.; Vrbanac, V. D.; Lingwood, D.

10.1101/2024.07.11.603156 — microbiology — Posted on 2024-07-12

3206 Stimulation Effects Mapping for Optimizing Coil Placement for Transcranial Magnetic Stimulation

Zhong, G.; Jin, F.; Ma, L.; Zhang, B.; Cao, D.; Li, J.; Zuo, N.; Fan, L.; Yang, Z.; Jiang, T.

10.1101/2024.02.23.581706 — bioengineering — Posted on 2024-07-12

3207 Replacement of Arabidopsis H2A.Z with human H2A.Z orthologs reveals extensive functional conservation and limited importance of the N-terminal tail sequence for Arabidopsis development

Sijacic, P.; Holder, D. H.; Krall, E. G.; Willett, C. G.; Foroozani, M.; Deal, R. B.

10.1101/2023.11.03.565555 — genetics — Posted on 2024-07-12

3208 Alignment Free Phylogeny Construction Using Maximum Likelihood Using k-mer Counts

Rahman, A. T. M. M.; Habib, S.; Islam, M. M.; Rahman, K. M.; Rahman, A.

10.1101/2023.12.05.570306 — evolutionary biology — Posted on 2024-07-12

3209 How much warming can mosquito vectors tolerate?

Couper, L.; Desire Uwera Nalukwago, D.; Lyberger, K.; Farner, J.; Mordecai, E. A.

10.1101/2024.01.03.574109 — ecology — Posted on 2024-07-12

3210 Cmai: Predicting Antigen-Antibody Interactions from Massive Sequencing Data

Song, B.; Wang, K.; Na, S.; Yao, J.; Fattah, F. J.; von Itzstein, M. S.; Yang, D. M.; Liu, J.; Xue, Y.; Liang, C.; Guo, Y.; Raman, I.; Zhu, C.; Dowell, J. E.; Homsi, J.; Rashdan, S.; Yang, S.; Gwin, M. E.; Hsiehchen, D.; Gloria-McCutchen, Y.; Raj, P.; Bai, X.; Wang, J.; Conejo-Garcia, J.; Xie, Y.; Gerber, D. E.; Huang, J.; Wang, T.

10.1101/2024.06.27.601035 — immunology — Posted on 2024-07-12

3211 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action

Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.

10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-12

3212 Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

Webster, A. N.; Becker, J. J.; Li, C.; Schwalbe, D. C.; Kerspern, D.; Karolczak, E. O.; Bundon, C.; Onoharigho, R. A.; Crook, M.; Jalil, M.; Godschall, E. N.; Dame, E. G.; Dawer, A.; Belmont-Rausch, D. M.; Pers, T. H.; Lutas, A.; Habib, N.; Guler, A. D.; Krashes, M. J.; Campbell, J. N.

10.1101/2023.10.31.564990 — neuroscience — Posted on 2024-07-12

3213 Convergent neural signatures of speech prediction error are a biological marker for spoken word recognition

Sohoglu, E.; Beckers, L.; Davis, M. H.

10.1101/2023.10.03.560649 — neuroscience — Posted on 2024-07-12

3214 Cooperative coding of continuous variables in networks with sparsity constraint

Züge, P.; Memmesheimer, R.-M.

10.1101/2024.05.13.593810 — neuroscience — Posted on 2024-07-12

3215 Justify your disability! A simulated medical evaluation as a robust novel stress induction paradigm in chronic pain patients

Chiron, A.; Fernandez, A.; Schmidt, L.; Plaza Wuthrich, S.; Suter, M. R.; Leknes, S.; Berna, C.

10.1101/2024.07.03.601919 — neuroscience — Posted on 2024-07-12

3216 Light-driven synchronization of optogenetic clocks

Cannarsa, M. C.; Liguori, F.; Pellicciotta, N.; Frangipane, G.; Di Leonardo, R.

10.1101/2023.10.24.563722 — synthetic biology — Posted on 2024-07-12

3217 Molecular response to multiple trace-element contamination of the European sardine

Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.

10.1101/2024.02.16.580673 — physiology — Posted on 2024-07-12

3218 Identification and quantification of transposable element transcripts using Long-Read RNA-seq in Drosophila germline tissues

Rebollo, R.; Gerenton, P.; Cumunel, E.; Mary, A.; Sabot, F.; Burlet, N.; Gillet, B.; Hughes, S.; Siqueira Oliveira, D.; Goubert, C.; Fablet, M.; Vieira, C.; Lacroix, V.

10.1101/2023.05.27.542554 — bioinformatics — Posted on 2024-07-12

3219 CParty: Hierarchically Constrained Partition Functionof RNA Pseudoknots

Trinity, L.; Gray, M.; Will, S.; Ponty, Y.; Stege, U.; Jabbari, H.

10.1101/2023.05.16.541023 — bioinformatics — Posted on 2024-07-12

3220 Terminal maturation of human reticulocytes to red blood cells by extensive remodelling and progressive liquid ordering of membrane lipids

Minetti, G.; Kaestner, L.; Köfeler, H.; Perotti, C.; Dorn, I.

10.1101/2023.06.02.543386 — biochemistry — Posted on 2024-07-12

3221 Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands

Lyu, Z.; Lyu, X.; Xia, G.; Carney, D.; Alves, V. M.; Falk, M.; Arora, N.; Zou, H.; McGrath, A.; Kang, Y.

10.1101/2024.07.08.602624 — biochemistry — Posted on 2024-07-12

3222 Multiresolution molecular dynamics simulations reveal the interplay between conformational variability and functional interactions in membrane-bound cytochrome 2B4

Han, S. B.; Teuffel, J.; Mukherjee, G.; Wade, R. C.

10.1101/2024.04.18.590076 — biochemistry — Posted on 2024-07-12

3223 Notch induces transcription by stimulating release of paused RNA Pol II without increasing chromatin accessibility

Rogers, J. M.; Mimoso, C. A.; Martin, B. J.; Martin, A. P.; Aster, J. C.; Adelman, K.; Blacklow, S. C.

10.1101/2024.06.13.598853 — genomics — Posted on 2024-07-12

3224 SynBot: An open-source image analysis software for automated quantification of synapses

Savage, J. T.; Ramirez, J.; Risher, W. C.; Wang, Y.; Irala, D.; Eroglu, C.

10.1101/2023.06.26.546578 — neuroscience — Posted on 2024-07-12

3225 Transcriptional and Cellular Response of hiPSC-derived Microglia-Neural Progenitor Co-Cultures Exposed to IL-6

Couch, A. C. M.; Brown, A.; Raimundo, C.; Solomon, S.; Taylor, M.; Sichlinger, L.; Matuleviciute, R.; Srivastava, D. P.; Vernon, A. C.

10.1101/2023.12.21.572748 — neuroscience — Posted on 2024-07-12

3226 Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Yao, M.; Wei, Z.; Nielsen, J. S.; Kakazu, A.; Ouyang, Y.; Li, R.; Chu, T.; Scafidi, S.; Lu, H.; Aggarwal, M.; Duan, W.

10.1101/2024.03.25.586662 — neuroscience — Posted on 2024-07-12

3227 TOR kinase controls Arabidopsis shoot development by translational repression of cytokinin catabolic enzymes

Janocha, D.; Pfeiffer, A.; Dong, Y.; Novak, O.; Strnad, M.; Ryabova, L.; Werner, T.; Lohmann, J. U.

10.1101/2021.07.29.454319 — plant biology — Posted on 2024-07-12

3228 Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer

Hofstad, M.; Woods, A.; Parra, K.; Sychev, Z. E.; Mazzagatti, A.; Yu, L.; Gilbreath, C.; Ly, P.; Drake, J. M.; Kittler, R.

10.1101/2024.07.10.602941 — cancer biology — Posted on 2024-07-12

3229 Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer

Aust, O.; Blanc, E.; Lüthen, M.; Hollek, V.; Astaburuaga-Garcia, R.; Klinger, B.; Trinks, A.; Beule, D.; Papke, B.; Horst, D.; Bluthgen, N.; Sers, C.; Der, C. J.; Morkel, M.

10.1101/2024.07.01.601542 — cancer biology — Posted on 2024-07-12

3230 Gap-App: A sex-distinct AI-based predictor for pancreatic ductal adenocarcinoma survival as a web application open to patients and physicians

Ojha, A.; Zhao, S.-J.; Zhang, J.-T.; Simo, K. A.; Liu, J.-Y.

10.1101/2024.06.04.597246 — bioinformatics — Posted on 2024-07-12

3231 Is facultative sex is the best of both worlds in the parasitoid wasp Lysiphlebus fabarum?

Boulton, R. A.

10.1101/2024.02.25.581911 — evolutionary biology — Posted on 2024-07-12

3232 Warm temperature inhibits cytoplasmic incompatibility induced by endosymbiotic Rickettsiella in a spider host

Proctor, J. D.; Mackevicius-Dubickaja, V.; Gottlieb, Y.; White, J.

10.1101/2024.04.17.589895 — ecology — Posted on 2024-07-12

3233 Temporally resolved single cell transcriptomics in a human model of amniogenesis

Sekulovski, N.; Carleton, A. E.; Rengarajan, A. A.; Lin, C.-W.; Juga, L. L.; Whorton, A. E.; Kropp Schmidt, J.; Golos, T.; Taniguchi, K.

10.1101/2023.09.07.556553 — developmental biology — Posted on 2024-07-12

3234 A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment

Abraham, E.; Volmert, B.; Roule, T.; Huang, L.; Yu, J.; Williams, A. E.; Cohen, H. M.; Douglas, A.; Megill, E.; Morris, A.; Stronati, E.; Fueyo, R.; Zubillaga, M.; Elrod, J. W.; Akizu, N.; Aguirre, A.; Estaras, C.

10.1101/2024.07.11.602981 — developmental biology — Posted on 2024-07-12

3235 Mutation of a highly conserved isoleucine residue in loop 2 of several ????-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental to infection

Kerr, C. M.; Pfannenstiel, J. J.; Alhammad, Y. M.; O'Connor, J. J.; Ghimire, R.; Shrestha, R.; Khattabi, R.; Saenjamsai, P.; Parthasarathy, S.; McDonald, P. R.; Gao, P.; Johnson, D. K.; More, S.; Roy, A.; Channappanavar, R.; Fehr, A. R.

10.1101/2024.01.03.574082 — microbiology — Posted on 2024-07-12

3236 Surveillance of H5 HPAI in Michigan using retail milk

Lauring, A. S.; Martin, E. T.; Eisenberg, M. C.; Fitzsimmons, W. J.; Salzman, E.; Leis, A. M.; Lyon-Callo, S.; Bagdasarian, N.

10.1101/2024.07.04.602115 — microbiology — Posted on 2024-07-12

3237 IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

McDougal, M. B.; De Maria, A. M.; Nakahara, E.; Boys, I. N.; Schoggins, J. W.

10.1101/2024.05.13.593954 — microbiology — Posted on 2024-07-12

3238 Single cell transcriptome profiling reveals pathogenesis of Bullous Pemphigoid

Wang, Y.; Liang, G.; Zhao, C.; Wei, Q.; Feng, S.

10.1101/2024.06.28.601141 — immunology — Posted on 2024-07-12

3239 Classification of Parkinson's Disease and Delineating Progression Markers from the Sebum Volatilome

Walton-Doyle, C.; Heim, B.; Sinclair, E.; Lim, S. H.; Hollywood, K.; Milne, J.; Holzknecht, E.; Stefani, A.; Hogl, B.; Seppi, K.; Silverdale, M.; Poewe, W.; Barran, P.; Trivedi, D. K.

10.1101/2023.03.01.530578 — neuroscience — Posted on 2024-07-12

3240 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance

Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.

10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-12

3241 Targeting cancer with small molecule pan-KRAS degraders

Popow, J.; Farnaby, W.; Gollner, A.; Kofink, C.; Fischer, G.; Wurm, M.; Zollman, D.; Wijaya, A.; Mischerikow, N.; Hasenoehrl, C.; Prokofeva, P.; Arnhof, H.; Arce-Solano, S.; Bell, S.; Boeck, G.; Diers, E.; Frost, A. B.; Goodwin-Tindall, J.; Karolyi-Oezguer, J.; Khan, S.; Klawatsch, T.; Koegl, M.; Kousek, R.; Kratochvil, B.; Kropatsch, K.; Lauber, A. A.; McLennan, R.; Olt, S.; Peter, D.; Petermann, O.; Roessler, V.; Stolt-Bergner, P.; Strack, P.; Strauss, E.; Trainor, N.; Vetma, V.; Whitworth, C.; Zhong, S.; Quant, J.; Weinstabl, H.; Küster, B.; Ettmayer, P.; Ciulli, A.

10.1101/2023.10.24.563163 — pharmacology and toxicology — Posted on 2024-07-12

3242 The future is fully defined: recombinant fragment E8 of laminin-511 is a viable xenofree alternative to Matrigel for hiPSC culture and differentiation into neurovascular cell types

Ferreira, L. A.; do Nascimento, D. F.; Tandon, I.; Cordes, L.; Balachandran, K.

10.1101/2024.06.20.599891 — bioengineering — Posted on 2024-07-12

3243 Unveiling the Structural Proteome of an Alzheimer's Disease Rat Brain Model

Khalili Samani, E.; Hasan, S. M. N.; Waas, M.; Keszei, A. F. A.; Xu, X.; Heydari, M.; Hill, M. E.; McLaurin, J.; Kislinger, T.; Mazhab-Jafari, M. T.

10.1101/2024.07.11.602936 — biochemistry — Posted on 2024-07-12

3244 Between-day reliability of local and global muscle-tendon unit assessments in female athletes whilst controlling for menstrual cycle phase

Newbould, S.; Walker, J.; Dinsdale, A. J.; Whitehead, S.; Nicholson, G.

10.1101/2024.06.23.600286 — physiology — Posted on 2024-07-12

3245 An MITF- and mTOR-dependent FLCN pathway suppresses TFE3-driven metastasis in melanoma

Chang, J.; Campbell-Hanson, K. R.; Vanneste, M.; Yevdash, J.; Bartschat, N. I.; Jiarui, J.; Bhinu, A.; Helverson, A.; Henry, M.; Steingrimsson, E.; Weigel, R. J.; Cornell, R.; Kenny, C.

10.1101/2024.07.11.603140 — cancer biology — Posted on 2024-07-12

3246 Cryo-EM Structures of Clostridium perfringens Enterotoxin Bound to its Human Receptor, Claudin-4

Rathnayake, S. S.; Erramilli, S. K.; Kossiakoff, A. A.; Vecchio, A. J.

10.1101/2024.07.11.603128 — biophysics — Posted on 2024-07-12

3247 A Retinoic Acid:YAP1 signaling axis controls atrial lineage commitment

Estaras, C.

10.1101/2024.07.11.602981 — developmental biology — Posted on 2024-07-12

3248 Continuous nuclear envelope surveillance is required for DNA double-strand break repair.

Medina-Suarez, S.; Machin, F.

10.1101/2024.07.12.603222 — cell biology — Posted on 2024-07-12

3249 KIF2A maintains cytokinesis in mouse embryonic stem cells by stabilising intercellular bridge microtubules

Stockmann, L.; Kabbech, H.; Kremers, G.-J.; van Herk, B.; Dille, B.; van den Hout, M.; van IJcken, W.; Dekkers, D. H. W.; Demmers, J. A.; Smal, I.; Huylebroeck, D.; Basu, S.; Galjart, N.

10.1101/2024.07.11.603034 — cell biology — Posted on 2024-07-12

3250 An in vivo screen for proteolytic switches that can mediate Notch activation

Jordan, T.; Baker, F.; Harman, J.; Walton, B.; Ajamu-Johnson, A.; Alashqar, R.; Struhl, G.; Langridge, P. D.

10.1101/2024.07.10.602225 — cell biology — Posted on 2024-07-12

3251 Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress.

De Lemos, D.; Soulet, A.-L.; Morales, V.; Berge, M.; Polard, P.; Johnston, C. H. G.

10.1101/2024.07.12.603235 — microbiology — Posted on 2024-07-12

3252 TIM-3 blockade enhances ex vivo stimulated allogeneic NK cell therapy for relapsed murine neuroblastoma after hematopoietic cell transplant

Quamine, A.; Mohrdieck, N. R.; King, C. A.; Griggs, A. A.; Kline, J. M.; Cho, M. M.; Rinella, S. P.; Tippins, K. E.; Bates, P. D.; Shi, L.; Song, L.; Hess, N. J.; Kearl, T. J.; Johnson, B. D.; Capitini, C. M.

10.1101/2024.07.09.602731 — immunology — Posted on 2024-07-12

3253 Sarm1-Dependent Metabolic Reprogramming of Schwann Cells Following Nerve Injury

Stepanova, E.; Cho, C.; Lee, J.; Pavelec, C. M.; Tripathi, A.; Vegiraju, T.; Hunter-Chang, S.; Leitinger, N.; Campbell, J. N.; Deppmann, C.

10.1101/2024.07.11.603162 — neuroscience — Posted on 2024-07-12

3254 Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

Ritchie, E. M.; Zhong, S.; Pu, Q.; Li, Y.; Zheng, B.; Jin, Y.

10.1101/2024.07.10.602846 — neuroscience — Posted on 2024-07-12

3255 Oxidative stress promotes axonal atrophy through alterations in microtubules and EB1 function

Shields, S.; Wilkes, O.; Gozes, I.; Sanchez-Soriano, N.

10.1101/2024.07.12.603221 — neuroscience — Posted on 2024-07-12

3256 Single-cell RNA-sequencing identifies unique cell-specific gene expression profiles in high-grade cardiac allograft vasculopathy

Amancherla, K.; Schlendorf, K. H.; Chow, N.; Sheng, Q.; Freedman, J. E.; Rathmell, J. C.

10.1101/2024.07.10.602989 — systems biology — Posted on 2024-07-12

3257 Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage

Huang, Z.; Luo, S.; Wang, Z.; Zhang, Z.; Jiang, B.; Nie, Q.; Zhang, J.

10.1101/2024.07.10.602845 — systems biology — Posted on 2024-07-12

3258 Nitrate activates a MKK3-dependent MAPK module via NLP transcription factors in Arabidopsis

Schenk, S. T.; Brehaut, V.; Chardin, C.; Boudsocq, M.; Marmagne, A.; Colcombet, J.; Krapp, A.

10.1101/2024.07.09.602786 — plant biology — Posted on 2024-07-12

3259 The Pollen Tube Penetrates the Synergid Cell by Formation of a Peritubular Membrane

Desnoyer, N.; Belloli, M.; Bencivenga, S.; Denninger, P.; Grossniklaus, U.

10.1101/2024.07.10.602759 — plant biology — Posted on 2024-07-12

3260 Coronary Microvascular Dysfunction is Associated with Augmented Lysosomal Signaling in Hypercholesterolemic Mice

Wang, Y.; Moura, A. K.; Zuo, R.; Zhou, W.; Wang, Z.; Roudbari, K.; Hu, J. Z.; Li, P.-L.; Zhang, Y.; Li, X.

10.1101/2024.07.10.603000 — pharmacology and toxicology — Posted on 2024-07-12

3261 Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer

Hofstad, M.; Woods, A.; Parra, K.; Sychev, Z. E.; Mazzagatti, A.; Yu, L.; Gilbreath, C.; Ly, P.; Drake, J. M.; Kittler, R.

10.1101/2024.07.10.602941 — cancer biology — Posted on 2024-07-12

3262 A long non-coding RNA LINC00094 regulates the transcriptional expression of lipid metabolism-related genes as a new member of core regulatory circuitry in esophageal squamous cell carcinoma

Peng, L.; Wang, Q.-Y.; Chen, J.-X.; Chen, Y.; Li, R.-Y.; Liao, L.-D.; Lin, W.; Li, C.; Li, E.-M.; Xu, L.

10.1101/2024.07.10.602928 — cancer biology — Posted on 2024-07-12

3263 Improved characterization of single-cell RNA-seq libraries with paired-end avidity sequencing

Chamberlin, J. T.; Gillen, A. E.; Quinlan, A. R.

10.1101/2024.07.10.602909 — genomics — Posted on 2024-07-12

3264 Fig4 confers tolerance to rapamycin in a Ste20-dependent manner independent of the Vac14 scaffold

Reeves, H. E.; King, A.; Khan, I.; Thomas, A.; Chung, C.; Dotson, L. D.; Sivaprakash, A.; Hall, H. A.; Habib, A.; Lee, S. R.; Lloyd, B. C.; Darbro, C. L.; Strunk, B. S.

10.1101/2024.07.12.603206 — cell biology — Posted on 2024-07-12

3265 L-type calcium channel blockade with verapamil prevents noise induced neuronal dyssynchrony

Yalcinoglu, S.; Braun, R. D.; Wattoo, A.; Apawu, A. K.; Alrayashi, R.; Holt, A. G.

10.1101/2024.07.10.602276 — neuroscience — Posted on 2024-07-12

3266 Oral cannabidiol administration in mice during pregnancy and lactation affects early postnatal body weight, fasting glucose, ingestive behavior, anxiety- and obsessive compulsive-like behaviors, and long-term object-memory in adult offspring in a sex-dependent manner

Krakora Compagno, M.; Silver, C. R.; Cox-Holmes, A.; Basso, K. B.; Bishop, C.; Bernstein, A. M.; Carley, A.; Cazorla, J.; Claydon, J.; Crane, A.; Crespi, C.; Curley, E.; Dolezel, T.; Franck, E.; Heiden, K.; Huffstettler, C. M.; Loeven, A. M.; May, C. A.; Maykut, N.; Narvarez, A.; Pacheco, F. A.; Turner, O.; Fadool, D. A.

10.1101/2024.07.10.602955 — neuroscience — Posted on 2024-07-12

3267 GlyTrait Brings Insights into Functional Glycosylation

Fu, B.; Wang, G.; Li, C.; Li, Y.; Liu, X.; Zhang, Y.; Lu, H.

10.1101/2024.07.09.602632 — bioinformatics — Posted on 2024-07-12

3268 Peri-centrosomal localization of small interfering RNAs in C. elegans

Jin, Q.; Feng, X.; Huang, X.; Guang, S.; Zhu, C.

10.1101/2024.07.11.603161 — genetics — Posted on 2024-07-12

3269 Repeated extrinsic and anisotropic mechanical inputs promote polarized adherens junction elongation

Yang, X.; Ferraro, T.; Molnar, K.; Pontabry, J.; Malanda, S.-R.; Maghelli, N.; Royer, L. A.; Grill, S. W.; Myers, E. W.; Grigolon, S.; Labouesse, M.

10.1101/2024.07.09.602689 — developmental biology — Posted on 2024-07-12

3270 Sleep induced by mechanosensory stimulation provides cognitive and health benefits in Drosophila

Inami, S.; Koh, K.

10.1101/2024.07.10.602891 — neuroscience — Posted on 2024-07-12

3271 Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response

Hendrickson, T.; Abigail Giese, A.; Fiedler, M.; Perez, W.; Reyes-Sanchez, E.; Reyes-Lozano, M.; Wang, S.; Venegas-Zamora, L.; Provasek, V.; El-Essawi, A.; Breitenbach, I.; Fakuade, F. E.; Kutschka, I.; Schiattarella, G. G.; Voigt, N.; Valderrabano, M.; Altamirano, F.

10.1101/2024.07.08.602618 — pathology — Posted on 2024-07-12

3272 Non-standard proteins in the lenses of AlphaFold3 - case study of amyloids

Wojciechowska, A. W.; Wojciechowski, J. W.; Kotulska, M.

10.1101/2024.07.09.602655 — bioinformatics — Posted on 2024-07-12

3273 Olfactory basis for essential amino acid perception during foraging in Caenorhabditis elegans

Siddiqui, R.; Mehta, N.; Ranjith, G.; Felix, M.-A.; Chen, C.; Singh, V.

10.1101/2024.07.11.603021 — animal behavior and cognition — Posted on 2024-07-12

3274 Activated SKN-1 alters the aging trajectories of long-lived C. elegans mutants

Curran, S.; Turner, C.

10.1101/2024.07.09.602737 — genetics — Posted on 2024-07-12

3275 Pond Water Microbiome Taxa Profiles and Antibiotic Resistance Genes Associated with Acidity and Tannins

Vaccaro, M.; Pilat, A. M.; Gusmano, L.; Pham, M. T. N.; Barich, D.; Gibson, A.; Epalle, M.; Frost, D. J.; Volin, E.; Slimak, Z. C.; Menke, C. C.; Fennessy, M. S.; Slonczewski, J. L.

10.1101/2024.07.10.602992 — microbiology — Posted on 2024-07-12

3276 Microbial consortia driving lignocellulose transformation in agricultural woodchip bioreactors

Schiml, V.; Walter, J.; Hagen, L. H.; Varnai, A.; Bergaust, L.; de Leon, A. V.-P.; Elsgaard, L.; Bakken, L. R.; Arntzen, M. O.

10.1101/2024.07.11.603112 — microbiology — Posted on 2024-07-12

3277 Malassezia responds to environmental pH signals through the conserved Rim/Pal pathway

Pianalto, K. M.; Telzrow, C. L.; Brown Harding, H.; Brooks, J. T.; Granek, J. A.; Gushiken Ibanez, E.; LeibundGut-Landmann, S.; Heitman, J. B.; Ianiri, G.; Alspaugh, J. A.

10.1101/2024.07.11.603086 — microbiology — Posted on 2024-07-12

3278 Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease

Menacho, C.; Okawa, S.; Alvarez-Merz, I.; Wittich, A.; Munoz-Oreja, M.; Lisowski, P.; Pentimalli, T. M.; Rybak-Wolf, A.; Inak, G.; Zakin, S.; Thevandavakkam, M.; Petersilie, L.; Zaliani, A.; Mlody, B.; Seibt, A.; Donnelly, J.; Woleben, K.; Fernandez-Checa, J.; Herebian, D.; Mayatepek, E.; Rajewsky, N.; Spinazzola, A.; Schuelke, M.; Perlstein, E.; Rossi, A.; Distelmaier, F.; Holt, I. J.; Pless, O.; Rose, C.; Del Sol, A.; Prigione, A.

10.1101/2024.07.08.602501 — neuroscience — Posted on 2024-07-12

3279 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging

Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Bouzignac, R.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.

10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-07-12

3280 SMYD5 is a regulator of the mild hypothermia response

Rafnsdottir, S.; Jang, K.; Halldorsdottir, S. T.; Vinod, M.; Tomasdottir, A.; Moller, K.; Halldorsdottir, K.; Reynisdottir, T.; Atladottir, L. H.; Allison, K. E.; Ostacolo, K.; He, J.; Zhang, L.; Northington, F. J.; Magnusdottir, E.; Chavez-Valdez, R.; Anderson, K. J.; Bjornsson, H.

10.1101/2023.05.11.540170 — genetics — Posted on 2024-07-12

3281 KLF6 in Pulmonary Hypertension: The Dual Role of Friend and Foe

Alharbi, R.; Fernandes, N.; Maude, H.; Fellows, A.; Williams, R. D.; Chen, C.-N.; Lambie, N.; Keles, M.; Matthews, N.; Al-Sahaf, M.; Guo, M.; Zhao, L.; Lawrie, A.; Whitsett, J. A.; Cebola, I.; Wojciak-Stothard, B.

10.1101/2024.07.08.602619 — cell biology — Posted on 2024-07-12

3282 Membrane binding properties of the cytoskeletal protein bactofilin

Liu, Y.; Karmakar, R.; Steinchen, W.; Mukherjee, S.; Bange, G.; Schafer, L. V.; Thanbichler, M.

10.1101/2024.06.14.599034 — microbiology — Posted on 2024-07-12

3283 Quadriceps-hamstrings muscle co-activation during the swing phase of walking is modulated by task constraints in healthy adults

Van Can, E. A. M.; Houdijk, H.; Buurke, T. J. W.

10.1101/2024.02.29.582454 — neuroscience — Posted on 2024-07-12

3284 Disentangling the Roles of Distinct Cell Classes with Cell-Type Dynamical Systems

Jha, A.; Gupta, D.; Brody, C. D.; Pillow, J. W.

10.1101/2024.07.08.602520 — neuroscience — Posted on 2024-07-12

3285 An Information Processing Pattern from Robotics Predicts Unknown Properties of the Human Visual System

Battaje, A.; Godinez, A.; Hanning, N. M.; Rolfs, M.; Brock, O.

10.1101/2024.06.20.599814 — neuroscience — Posted on 2024-07-12

3286 Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction

Abramian, A.; Hoogstraaten, R. I.; Murphy, F. H.; mcDaniel, K. F.; Toonen, R. F.; Verhage, M.

10.1101/2024.01.05.574432 — neuroscience — Posted on 2024-07-12

3287 Autophagosome development and chloroplast segmentation occur synchronously for piecemeal degradation of chloroplasts

Izumi, M.; Nakamura, S.; Otomo, K.; Ishida, H.; Hidema, J.; Nemoto, T.; Hagihara, S.

10.1101/2023.10.11.561947 — plant biology — Posted on 2024-07-12

3288 Host-specific effects of a generalist parasite of mosquitoes

Zeferino, T. G.; Koella, J. C.

10.1101/2024.02.09.579598 — evolutionary biology — Posted on 2024-07-12

3289 ARF1 compartments direct cargo flow via maturation into recycling endosomes

Stockhammer, A.; Adarska, P.; Natalia, V.; Heuhsen, A.; Klemt, A.; Bregu, G.; Harel, S.; Rodilla-Ramirez, C.; Spalt, C.; Oezsoy, E.; Leupold, P.; Grindel, A.; Fox, E.; Mejedo, J. O.; Zehtabian, A.; Ewers, H.; Puchkov, D.; Haucke, V.; Bottanelli, F.

10.1101/2023.10.27.564143 — cell biology — Posted on 2024-07-12

3290 Priming lymphocyte responsiveness and differential T cell signaling in pediatric IBD patients with Cannabis use.

Sanctuary, M. R.; Hudacheck, C. L.; Jones, A. J.; Murphy, B. V.; Welsh, N.; Klawitter, J.; Hoffenberg, E. J.; Collins, C. B.

10.1101/2024.07.08.602495 — immunology — Posted on 2024-07-12

3291 Epidural Spinal Cord Recordings (ESRs): Sources of Artifact in Stimulation Evoked Compound Action Potentials

Deshmukh, A.; Settell, M. L.; Cheng, K. L.; Knudsen, B.; Trevathan, J. K.; LaLuzerne, M.; Blanz, S.; Skubal, A.; Verma, N.; Romanauski, B.; Brucker-Hahn, M.; Lam, D.; Lavrov, I.; Suminski, A.; Weber, D.; Fisher, L.; Lempka, S.; Shoffstall, A.; Park, H.; Ross Ellison, E.; Zhang, M.; Ludwig, K.

10.1101/2024.05.17.594739 — neuroscience — Posted on 2024-07-12

3292 Development of a DSM test battery to determine depression-like marmoset

Yamanaka, H.; Ishibashi, H.; Nakamura, K.

10.1101/2024.07.08.602574 — neuroscience — Posted on 2024-07-12

3293 Structure of the Calvin-Benson-Bassham sedoheptulose-1,7-bisphosphatase SBPase from the model microalga Chlamydomonas reinhardtii

Le Moigne, T.; Santoni, M.; Jomat, L.; Lemaire, S. D.; Zaffagnini, M.; Cheron, N.; Henri, J.

10.1101/2022.10.28.514230 — biochemistry — Posted on 2024-07-12

3294 Converting Organic Municipal Solid Waste into Volatile Fatty Acids and Biogas: Experimental Pilot and Batch Studies with Statistical Analysis

Borhany, H.

10.1101/2023.06.21.545938 — microbiology — Posted on 2024-07-12

3295 Nitrogen Availability and Utilisation of Oligopeptides by Yeast in Industrial Scotch Grain Whisky Fermentation

Berg, H. Y.; Arju, G.; Nisamedtinov, I.

10.1101/2024.07.02.601656 — microbiology — Posted on 2024-07-12

3296 Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing and FastSurfer on MRI Processing

Hubner, S.; Tambalo, S.; Novello, L.; Hilbert, T.; Kober, T.; Jovicich, J.

10.1101/2024.07.05.602237 — neuroscience — Posted on 2024-07-12

3297 Non-feature-specific elevated responses and feature-specific backward replay in human brain induced by visual sequence exposure

He, T.; Gong, X.; Wang, Q.; Zhu, X.; Liu, Y.; Fang, F.

10.1101/2023.09.07.556631 — neuroscience — Posted on 2024-07-12

3298 Effects of context changes on memory reactivation

Ozdemir, S.; Senturk, Y. D.; Unver, N.; Demircan, C.; Olivers, C. N. L.; Egner, T.; Gunseli, E.

10.1101/2024.03.20.585920 — neuroscience — Posted on 2024-07-12

3299 PEELing: an integrated and user-centric platform for spatially-resolved proteomics data analysis

Peng, X.; Clements, J.; Jiang, Z.; Han, S.; Preibisch, S.; Li, J.

10.1101/2023.04.21.537871 — systems biology — Posted on 2024-07-12

3300 Proteins Derived From MRL/MpJ Tendon Provisional Extracellular Matrix and Secretome Promote Pro-Regenerative Tenocyte Behavior

Marvin, J. C.; Liu, E. J.; Chen, H. H.; Shiovitz, D. A.; Andarawis-Puri, N.

10.1101/2024.07.08.602500 — bioengineering — Posted on 2024-07-12

3301 Hierarchical structural organization in bioinspired peptide coacervate microdroplets

Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.

10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-12

3302 Increased inflammatory signature in myeloid cells of non-small cell lung cancer patients with high clonal hematopoiesis burden

Sim, H.; Park, H. J.; Park, G.-H.; Kim, Y. J.; Park, W.-Y.; Lee, S.-H.; Choi, M.

10.1101/2024.01.02.573827 — genomics — Posted on 2024-07-12

3303 Nitrogen metabolism in the picoalga Pelagomonas calceolata: disentangling cyanate lyase function under different nutrient conditions.

Guerin, N.; Seyman, C.; Orvain, C.; Bertrand, L.; Gourvil, P.; Probert, I.; Vacherie, B.; Brun, E.; Magdelenat, G.; Labadie, K.; Wincker, P.; Thurotte, A.; Carradec, Q.

10.1101/2024.02.19.580968 — genomics — Posted on 2024-07-12

3304 Comprehensive profiling of transcriptional regulation in cartilage reveals pathogenesis of osteoarthritis

Tian, W.; Dong, S.-S.; Jiang, F.; Zhang, J.-Q.; Wang, C.; He, C.-Y.; Hu, S.-Y.; Hao, R.-H.; Song, H.-M.; Gao, H.-W.; An, K.; Zhu, D.-L.; Yang, Z.; Guo, Y.; Yang, T.-L.

10.1101/2024.06.11.598401 — genetics — Posted on 2024-07-12

3305 On the nature of the earliest known life forms

Kanaparthi, D.; Westall, F.; Lampe, M.; Zhu, B.; Boesen, T.; Klingl, A.; Schwille, P.; Lueders, T.

10.1101/2021.08.16.456462 — evolutionary biology — Posted on 2024-07-12

3306 Drivers of thermal tolerance breadth of plants across contrasting biomes: do mean or seasonality in climate indices matter more?

Briceno, V. F.; Arnold, P. A.; Cook, A. M.; Courtney Jones, S. K.; Gallagher, R. V.; French, K.; Bravo, L. A.; Nicotra, A. B.; Leigh, A.

10.1101/2023.10.02.560437 — ecology — Posted on 2024-07-12

3307 Contraction-induced endocardial id2b plays a dual role in regulating myocardial contractility and valve formation

Chen, S.; Yin, J.; Liang, J.; Zhang, W.; Jiang, P.; Wang, W.; Chen, X.; Zhou, Y.; Xia, P.; Yang, F.; Gu, Y.; Zhang, R.; Han, p.

10.1101/2024.05.09.593293 — developmental biology — Posted on 2024-07-12

3308 Shaping and interpretation of Dpp morphogen gradient by endocytic trafficking

Rasouliha, S. H.; Aguilar, G.; Reinger, C.; Matsuda, S.

10.1101/2023.03.27.534445 — developmental biology — Posted on 2024-07-12

3309 Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest

Casey-Clyde, T.; Liu, S. J.; Serrano, J. A. C.; Teng, C.; Jang, Y.-G.; Vasudevan, H. N.; Bush, J. O.; Raleigh, D. R.

10.1101/2024.03.13.584903 — developmental biology — Posted on 2024-07-12

3310 A progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans

Romero-Bueno, R.; Fragoso-Luna, A.; Ayuso, C.; Mellmann, N.; Kavsek, A.; Riedel, C. G.; Ward, J. D.; Askjaer, P.

10.1101/2024.03.17.585430 — cell biology — Posted on 2024-07-12

3311 Telomemore enables single-cell analysis of cell cycle and chromatin condensation

Yakovenko, I.; Mihai, I. S.; Selinger, M.; Rosenbaum, W.; Dernstedt, A.; Groning, R.; Trygg, J.; Carroll, L.; Forsell, M.; Henriksson, J.

10.1101/2023.03.19.533267 — immunology — Posted on 2024-07-12

3312 Serotonergic amplification of odor-evoked neural responses maps flexibly onto behavioral outcomes

Bessonova, Y.; Raman, B.

10.1101/2023.08.08.552516 — neuroscience — Posted on 2024-07-12

3313 TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis

Ju, Q.; Sheng, W.; Zhang, M.; Chen, J.; Wu, L.; Liu, X.; Fang, W.; Shi, H.; Sun, C.

10.1101/2024.03.22.586256 — cancer biology — Posted on 2024-07-12

3314 Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries

Ling, Y. H.; Liang, C.; Wang, S.; Wu, C.

10.1101/2024.07.08.602478 — biophysics — Posted on 2024-07-12

3315 Complex-based Ligand-Binding Proteins Redesign by Equivariant Diffusion-based Generative Models

Nguyen, V. T. D.; Nguyen, N.; Hy, T. S.

10.1101/2024.04.17.589997 — bioinformatics — Posted on 2024-07-12

3316 Development of robust antiviral assays using relevant apical-out human airway organoids

Lee, J.-H.; LeCher, J. C.; Parigoris, E.; Shinagawa, N.; Sentosa, J.; Manfredi, C.; Goh, S. L.; De, R.; Tao, S.; Zandi, K.; Amblard, F.; Sorscher, E. J.; Spence, J. R.; Tirouvanziam, R.; Schinazi, R. F.; Takayama, S.

10.1101/2024.01.02.573939 — bioengineering — Posted on 2024-07-12

3317 Sibling Similarity Can Reveal Key Insights Into Genetic Architecture

Souaiaia, T.; Wu, H. M.; Hoggart, C.; O'Reilly, P.

10.1101/2023.02.19.529159 — genetics — Posted on 2024-07-12

3318 Transcription Factor Condensates Mediate Clustering of MET Regulon and Enhancement in Gene Expression

Lee, J.; Simpson, L.; Li, Y.; Becker, S.; Zou, F.; Zhang, X.; Bai, L.

10.1101/2024.02.06.579062 — genetics — Posted on 2024-07-12

3319 An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging neurons

Abdelmageed, M.; Palamisamy, P.; Vernail, V.; Silberman, Y.; Paul, S.; Paul, A.

10.1101/2023.09.27.559771 — neuroscience — Posted on 2024-07-12

3320 Mechanism of membrane curvature generation and caveola formation by flat disc-like complexes of caveolin

Barnoy, A.; Parton, R. G.; Kozlov, M. M.

10.1101/2024.07.09.602763 — biophysics — Posted on 2024-07-12

3321 Noncanonical roles of ATG5 and membrane atg8ylation in retromer assembly and function

Paddar, M. A.; Wang, F.; Trosdal, E.; Hendrix, E.; He, Y.; Salemi, M. R.; Mudd, M.; Jia, J.; Duque, T.; Javed, R.; Phinney, B. S.; Deretic, V.

10.1101/2024.07.10.602886 — cell biology — Posted on 2024-07-12

3322 RABGAP1 acts as a sensor to facilitate sorting and processing of amyloid precursor protein

Eden, J.; Kaufman, J. G. G.; Cattin-Ortola, J.; Benedetti, L.; Nieuwenhuis, B.; Owen, D. J.; Lippincott-Schwartz, J.; Munro, S.; Gershlick, D. C.

10.1101/2024.07.11.602925 — cell biology — Posted on 2024-07-12

3323 Septins function in exocytosis via physical interactions with the exocyst complex in fission yeast cytokinesis

Singh, D.; Liu, Y.; Zhu, Y.-H.; Zhang, S.; Naegele, S.; Wu, J.-Q.

10.1101/2024.07.09.602728 — cell biology — Posted on 2024-07-12

3324 Amino acids trigger MDC-dependent mitochondrial remodeling by altering mitochondrial function

Raghuram, N.; Hughes, A.

10.1101/2024.07.09.602707 — cell biology — Posted on 2024-07-12

3325 Cytosol-living Trypanosoma cruzi amastigotes scavenge cholesterol from host ER and Golgi complex

Alcantara, C. d. L.; Pereira, M. G.; De Souza, W.; Cunha-e-Silva, N. L.

10.1101/2024.07.10.602841 — cell biology — Posted on 2024-07-12

3326 Blebs regulate phosphoinositides distribution and promote cell survival through the Septin-SH3KBP1-PI3K axis

Zhen, Z.; Zhang, C.; Li, J.; Wu, C.

10.1101/2024.07.09.602823 — cell biology — Posted on 2024-07-12

3327 The replication principle revisited: a shared functional organization between pulvinar-cortical and cortico-cortical connectivity and its structural and molecular imaging correlates

Basile, G. A.; Ielo, A.; Bonanno, L.; Cerasa, A.; Santoro, G.; Milardi, D.; Anastasi, G. P.; Torre, A.; Baldari, S.; Laudicella, R.; Gaeta, M.; Quartu, M.; Serra, M. P.; Trucas, M.; Quartarone, A.; Saranathan, M.; Cacciola, A.

10.1101/2024.07.11.603063 — neuroscience — Posted on 2024-07-12

3328 Brain Segregation and Integration Relate to Word-Finding Abilities in Older and Younger Adults

Oosterhuis, E. J.; Bailey, N.; Slade, K.; May, P. J. C.; Nuttall, H. E.

10.1101/2024.07.11.603138 — neuroscience — Posted on 2024-07-12

3329 A multiomic atlas of human early skeletal development

To, K.; Fei, L.; Pett, J. P.; Roberts, K.; Polanski, K.; Li, T.; Yayon, N.; He, P.; Xu, C.; Cranley, J.; Li, R.; Kanemaru, K.; Huang, N.; Megas, S.; Richardson, L.; Kapuge, R.; Perera, S.; Tuck, E.; Wilbrey-Clark, A.; Mulas, I.; Memi, F.; Cakir, B.; Predeus, A. V.; Horsfall, D.; Murray, S.; Prete, M.; Mazin, P.; He, X.; Meyer, K. B.; Haniffa, M.; Barker, R. A.; Bayraktar, O.; Buckley, C. D.; Teichmann, S. A.

10.1101/2024.07.10.602965 — developmental biology — Posted on 2024-07-12

3330 PRMT1-SFPQ regulates intron retention to control matrix gene expression during craniofacial development

Raulino Lima, J.; Ungvijanpunya, N.; Chen, Q.; Park, G.; Vatankhah, M.; Rosen, T.; Chai, Y.; Merrill, A. E.; Peng, W.; Xu, J.

10.1101/2024.07.09.598733 — developmental biology — Posted on 2024-07-12

3331 A shared threat-anticipation circuit is dynamically engaged at different moments by certain and uncertain threat

Cornwell, B. R.; Didier, P. R.; Grogans, S. E.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Hur, J.; Scott, Z. S.; Fox, A. S.; DeYoung, K. A.; Smith, J. F.; Shackman, A. J.

10.1101/2024.07.10.602972 — neuroscience — Posted on 2024-07-12

3332 Proteostasis Landscapes of Selective versus Poorly Responsive CFTR Variants Reveals Structural Vulnerabilities to Correction

McDonald, E. F.; Kim, M.; Olson, J. A.; Meiler, J.; Plate, L.

10.1101/2024.07.10.602964 — biochemistry — Posted on 2024-07-11

3333 Rational Design of a Flavoenzyme for Aerobic Nicotine Catabolism

Xu, P.; Tang, H.; Hu, H.; Xu, Z.; Zhang, Z.; Stull, F.; Song, P.

10.1101/2024.07.11.603087 — molecular biology — Posted on 2024-07-11

3334 The fate of secretory cells during intestinal homeostasis, regeneration, and tumor formation is regulated by Tcf4

Janeckova, L.; Stastna, M.; Hrckulak, D.; Berkova, L.; Kubovciak, J.; Onhajzer, J.; Kriz, V.; Dostalikova, S.; Mullerova, T.; Vecerkova, K.; Tenglerova, M.; Coufal, S.; Kostovcikova, K.; Blumberg, R. S.; Filipp, D.; Basler, K.; Valenta, T.; Kolar, M.; Korinek, V.

10.1101/2024.07.11.603019 — molecular biology — Posted on 2024-07-11

3335 Commensal-pathogen dynamics structure disease outcomes during Clostridioides difficile colonization

Fishbein, S.; DeVeaux, A. L.; Khanna, S.; Ferreiro, A. L.; Liao, J.; Agee, W.; Ning, J.; Mahmud, B.; Wallace, M. J.; Hink, T.; Reske, K. A.; Guruge, J.; Leekha, S.; Dubberke, E. R.; Dantas, G.

10.1101/2024.07.11.603094 — microbiology — Posted on 2024-07-11

3336 The skin microbiome as a new potential biomarker in the domestication and welfare of Octopus vulgaris

Costas-Imbernon, D.; Costas-Prado, C.; Sequeiro, T.; Tourinan, P.; Garcia-Fernandez, P.; Tur, R.; Chavarrias, D.; Saura, M.; Rotllant, J.

10.1101/2024.07.11.602832 — microbiology — Posted on 2024-07-11

3337 G-Quadruplex Structures in 16S rRNA Regions Correlate with Thermal Adaptation in Prokaryotes

Lyu, B.; Song, Q.

10.1101/2024.07.11.603124 — microbiology — Posted on 2024-07-11

3338 Expansion and revision of the genus Xanthobacter and proposal of Roseixanthobacter gen. nov.

Soltysiak, M. P. M.; Jalihal, A. P.; Christophersen, C. E.; Ory, A. L. H.; Lee, A. D.; Boulton, J. M.; Springer, M.

10.1101/2024.07.11.603134 — microbiology — Posted on 2024-07-11

3339 Phages carry orphan antitoxin-like enzymes to neutralize the DarTG1 toxin-antitoxin defense system

Johannesman, A.; Carlson, N. A.; LeRoux, M.

10.1101/2024.07.11.602962 — microbiology — Posted on 2024-07-11

3340 SSR42 is a Novel Regulator of Cytolytic Activity in Staphylococcus aureus

Jobson, M.-E.; Tomlinson, B. R.; Mustor, E. M.; Felton, E. A.; Weiss, A.; Caswell, C. C.; Shaw, L. N.

10.1101/2024.07.11.603084 — microbiology — Posted on 2024-07-11

3341 Using breathing systems in anaesthesia for up to 7 days instead of 24 hours: a comparative microbial safety study

Haanappel, C. P.; Rieff, E. A.; Pavkovic, L.; van Holst-Raaphorst, M. N.; de Groot, W.; van der Marel, C. D.; Voor in 't holt, A. F.; Severin, J. A.

10.1101/2024.07.11.603054 — microbiology — Posted on 2024-07-11

3342 mettannotator: a comprehensive and scalable Nextflow annotation pipeline for prokaryotic assemblies

Gurbich, T. A.; Beracochea, M.; De Silva, N. H.; Finn, R. D.

10.1101/2024.07.11.603040 — bioinformatics — Posted on 2024-07-11

3343 Functionally Validated Proteome-Wide Bioinformatic Annotation of the Monotopic Phosphoglycosyl Transferase Family

Durand, T.; Dodge, G. J.; Siuda, R. P.; Higinbotham, H. R.; Arbour, C. A.; Ghosh, S.; Allen, K. N.; Imperiali, B.

10.1101/2024.07.10.602977 — biochemistry — Posted on 2024-07-11

3344 Therapeutic Peptide SS-31 Modulates Membrane Binding and Aggregation of Alpha-Synuclein and Restores Impaired Mitochondrial Function

Stefaniak, E.; Cui, B.; Sun, K.; Yan, X.; Teng, X.; Ying, L.

10.1101/2024.07.11.603085 — biochemistry — Posted on 2024-07-11

3345 Direct testing of natural twister ribozymes from over a thousand organisms reveals a broad tolerance for structural imperfections

McKinley, L. N.; Meyer, M. O.; Sebastian, A.; Chang, B. K.; Messina, K. J.; Albert, I.; Bevilacqua, P. C.

10.1101/2024.07.11.603121 — biochemistry — Posted on 2024-07-11

3346 Contrasting kinetics of highly similar chloroalkane reductive dehalogenases

Picott, K.; Edwards, E. A.

10.1101/2024.07.10.602960 — biochemistry — Posted on 2024-07-11

3347 The Fc fragment of soluble IgMs binds C1q to activate the classical complement pathway, while inhibiting complement-dependent cytotoxicity

Pinto, A. J.; Chouquet, A.; Bally, I.; Thielens, N. M.; Dumestre-Perard, C.; Kunert, R.; Gaboriaud, C.; Ling, W. L. W.; REISER, J.-B.

10.1101/2024.07.10.602503 — biochemistry — Posted on 2024-07-11

3348 Optical Fibers Functionalized with Single-Walled Carbon Nanotubes for Flexible Fluorescent Catecholamine Detection

Klinger, M. E.; Miller, R. A.; Wilbrecht, L.; Landry, M. P.

10.1101/2024.07.09.602792 — biochemistry — Posted on 2024-07-11

3349 Systematic characterization of indel variants using a yeast-based protein folding sensor

Larsen-Ledet, S.; Lindemose, S.; Panfilova, A.; Gersing, S.; Suhr, C. H.; Genzor, A. V.; Lanters, H.; Nielsen, S. V.; Lindorff-Larsen, K.; Winther, J. R.; Stein, A.; Hartmann-Petersen, R.

10.1101/2024.07.11.603017 — biochemistry — Posted on 2024-07-11

3350 Metabolic PCTA-Based Shift Reagents for the Selective Detection of Extracellular Lactate Using CEST MRI

Chiaffarelli, R.; Cruz, P.; Zimmermann, M.; Geraldes, C. F. G. C.; Jurek, P.; F. Martins, A.

10.1101/2024.07.09.602789 — biochemistry — Posted on 2024-07-11

3351 Basal p53 maintains a distinct transcriptional program from irradiated p53 in tissue, including tumor suppressors

Zhou, R. W.; Manfredi, J.; Silverman, L.; Parsons, R. E.

10.1101/2024.07.11.601367 — biochemistry — Posted on 2024-07-11

3352 VARP binds SNX27 to promote endosomal supercomplex formation on membranes

Chandra, M.; Kendall, A.; Ford, M.; Jackson, L. P.

10.1101/2024.07.11.603126 — biochemistry — Posted on 2024-07-11

3353 Unveiling the Structural Proteome of an Alzheimer's Disease Rat Brain Model

Khalili Samani, E.; Hasan, S. M. N.; Wass, M.; Keszei, A. F. A.; Xu, X.; Heydari, M.; Hill, M. E.; McLaurin, J.; Kislinger, T.; Mazhab-Jafari, M. T.

10.1101/2024.07.11.602936 — biochemistry — Posted on 2024-07-11

3354 Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential

Rabbito, A.; Otun, O.; Fumagalli, A.; Seveno, M.; Galant, S.; Counson, M.; Durroux, T.; Bechara, C.; Smit, M. J.; Granier, S.; Szpakowska, M.; Chevigne, A.; Chaumont-Dubel, S.; Marin, P.

10.1101/2024.07.10.602459 — biochemistry — Posted on 2024-07-11

3355 Ketogenesis supports hepatic polyunsaturated fatty acid homeostasis via fatty acid elongation

Queathem, E. D.; Moazzami, Z.; Stagg, D. B.; Nelson, A. B.; Fulghum, K.; Hayir, A.; Seay, A.; Gillingham, J. R.; d`Avignon, D. A.; Han, X.; Ruan, H.-B.; Crawford, P. A.; Puchalska, P.

10.1101/2024.07.09.602593 — biochemistry — Posted on 2024-07-11

3356 Quadrupia: Derivation of G-quadruplexes for organismal genomes across the tree of life

Chantzi, N.; Nayak, A.; Baltoumas, F. A.; Aplakidou, E.; Liew, S. W.; Galuh, J. E.; Patsakis, M.; Moeckel, C.; Mouratidis, I.; Sazed, S. A.; Guiblet, W.; Montgomery, A.; Karmiris-Obratanski, P.; Guliang, W.; Zaravinos, A.; Vasquez, K. M.; Kwok, C. K.; Pavlopoulos, G.; Georgakopoulos-Soares, I.

10.1101/2024.07.09.602008 — genomics — Posted on 2024-07-11

3357 Mitoregulin self-associates to form likely homo-oligomeric pore-like structures

Linzer, C. R.; Stein, C. S.; Witmer, N. H.; Xu, Z.; Schnicker, N. J.; Boudreau, R. L.

10.1101/2024.07.10.601956 — molecular biology — Posted on 2024-07-11

3358 Association study of Plasmodium falciparum Acetyl-CoA Synthetase Mutations S868G and V949I with antimalarial drugs

Zhao, W.; Xiang, Z.; Zeng, W.; Qin, Y.; Pan, M.; Wu, Y.; Duan, M.; Mou, Y.; Liang, T.; Zhang, Y.; Liu, C.; Tang, X.; Huang, Y.; Yang, G.; Cui, L.; Yang, Z.

10.1101/2024.07.10.602966 — microbiology — Posted on 2024-07-11

3359 Bacterial Protein Signatures Identified in Porphyromonas gingivalis Containing-Autophagic Vacuoles Reveal Evolutionary History Between Oral Red/Orange Complex Bacteria and Gut Resident Bacteria

Paul, A.; Wellslager, B.; Williamson, M.; Yilmaz, O.

10.1101/2024.07.11.602567 — microbiology — Posted on 2024-07-11

3360 Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia

Jones, B. C.; Benedetti, G.; Cala, G.; Tullie, L.; Simcock, I.; Lutman, R.; Balys, M.; Amiri, R.; Sufi, J.; Arthurs, O.; Eaton, S.; Anderson, G.; Elvassore, N.; Li, V. S.; Jones, K. D.; Tape, C. J.; Luni, C.; Giobbe, G. G.; De Coppi, P.

10.1101/2024.07.08.602480 — cell biology — Posted on 2024-07-11

3361 Global regulation via modulation of ribosome pausing by the ABC-F protein EttA

Ousalem, F.; Ngo, S.; Oiffer, T.; Omairi-Nasser, A.; Monlezun, L.; Boel, G.

10.1101/2023.10.17.562674 — microbiology — Posted on 2024-07-11

3362 Acute rapamycin treatment reveals novel mechanisms of behavioral, physiological, and functional dysfunction in a maternal inflammation mouse model of autism and sensory over-responsivity

Le Belle, J. E.; Condro, M.; Cepeda, C.; Oikonomou, K. D.; Tessema, K.; Dudley, L.; Schoenfield, J.; Kawaguchi, R.; Geschwind, D.; Silva, A. J.; Zhang, Z.; Shokat, K.; Harris, N. G.; Kornblum, H. I.

10.1101/2024.07.08.602602 — neuroscience — Posted on 2024-07-11

3363 VTA μ-opioidergic neurons facilitate low sociability in protracted opioid withdrawal

Jo, A. Y.; Xie, Y.; Rodrigues, A.; Sandoval Ortega, R. A.; Creasy, K. T.; Beier, K. T.; Blendy, J. A.; Corder, G.

10.1101/2024.07.08.602522 — neuroscience — Posted on 2024-07-11

3364 Goal-directed action preparation in humans entails a mixture of corticospinal neural computations

Wadsley, C. G.; Nguyen, T.; Horton, C.; Greenhouse, I.

10.1101/2024.07.08.602530 — neuroscience — Posted on 2024-07-11

3365 Global genomics of the man-o'-war (Physalia) reveals biodiversity at the ocean surface

Church, S. H.; Abedon, R. B.; Ahuja, N.; Anthony, C. J.; Ramirez, D. A.; Rojas, L. M.; Albinsson, M. E.; Alvarez Trasobares, I.; Bergemann, R. E.; Bogdanovic, O.; Burdick, D. R.; Cunha, T. J.; Damian-Serrano, A.; D'Elia, G.; Dion, K.; Doyle, T. K.; Goncalves, J. M.; Gonzalez Rajal, A.; Haddock, S. H. D.; Helm, R. R.; Le Gouvello, D.; Lewis, Z. R.; Magalhaes, B. I. M. M.; Manko, M. K.; de Mendoza, A.; Moura, C. J.; Nel, R.; Perelman, J. N.; Prieto, L.; Munro, C.; Oguchi, K.; Pitt, K. A.; Schaeffer, A.; Schmidt, A. L.; Sellanes, J.; Wilson, N. G.; Yamamoto, G.; Lazo-Wasem, E.; Simon, C.; Decker,

10.1101/2024.07.10.602499 — zoology — Posted on 2024-07-11

3366 Multi-dataset Integration and Residual Connections Improve Proteome Prediction from Transcriptomes using Deep Learning

Cranney, C. W.; Meyer, J. G.

10.1101/2024.07.08.602560 — systems biology — Posted on 2024-07-11

3367 PTMNavigator: Interactive Visualization of Differentially Regulated Post-Translational Modifications in Cellular Signaling Pathways

Mueller, J.; Bayer, F. P.; Wilhelm, M.; Schuh, M. G.; Kuster, B.; The, M.

10.1101/2023.08.31.555601 — systems biology — Posted on 2024-07-11

3368 Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells

Ohlstrom, D.; Bakhtia, M.; Mumme, H.; Michaud, M.; Chien, F.; Pilcher, W.; Satpathy, S.; Jordan, S.; Bhasin, S.; Bhasin, M.

10.1101/2024.07.09.602801 — cancer biology — Posted on 2024-07-11

3369 Selective Activation of GPCRs: Molecular Dynamics Investigation of Siponimod's Interaction with S1PR1 and S1PR2

Soniya, K.; Nanduru, C.; Halder, A.

10.1101/2024.07.08.602194 — biophysics — Posted on 2024-07-11

3370 A molecular view into the structure and dynamics of phase-separated chromatin

Golembeski, A.; Lequieu, J.

10.1101/2024.07.08.602582 — biophysics — Posted on 2024-07-11

3371 Single-nanoparticle electrophoretic mobility and trapping using active-feedback 3D tracking

Johnson, A.; Welsher, K.

10.1101/2024.07.08.602591 — biophysics — Posted on 2024-07-11

3372 Computational Insights into the molecular dynamics of the binding of ligands in the Methanol Dehydrogenase

Lee, O.-S.; Lee, S. H.

10.1101/2024.07.08.602606 — biophysics — Posted on 2024-07-11

3373 The impact of Library Size and Scale of Testing on Virtual Screening

Liu, F.; Mailhot, O.; Glenn, I. S.; Vigneron, S. F.; Bassim, V.; Xu, X.; Valencia, K. F.; Smith, M. S.; Radchenko, D. S.; Fraser, J. S.; Moroz, Y. S.; Irwin, J. J.; Shoichet, B. K.

10.1101/2024.07.08.602536 — biophysics — Posted on 2024-07-11

3374 lociPARSE: a locality-aware invariant point attention model for scoring RNA 3D structures

Tarafder, S.; Bhattacharya, D.

10.1101/2023.11.04.565599 — bioinformatics — Posted on 2024-07-11

3375 Optimizing murine sample sizes for RNA-seq studies revealed from large-scale comparative analysis

Halasz, G.; Schmahl, J.; Negron, N.; Ni, M.; Atwal, G. S.; Glass, D. J.

10.1101/2024.07.08.602525 — bioinformatics — Posted on 2024-07-11

3376 Array Detection Enables Large Localization Range for Simple and Robust MINFLUX

Slenders, E.; Patil, S.; Held, M. O.; Zunino, A.; Vicidomini, G.

10.1101/2024.07.08.602588 — bioengineering — Posted on 2024-07-11

3377 AI-driven high-throughput droplet screening of cell-free gene expression

Zhu, J.; Meng, Y.; Gao, W.; Yang, S.; Zhu, W.; Ji, X.; Zhai, X.; Liu, W.; Luo, Y.; Ling, S.; Li, J.; Liu, Y.

10.1101/2024.07.04.602084 — bioengineering — Posted on 2024-07-11

3378 Calibration of instrumented treadmills using an instrumented pole; a modified version to use relatively smaller forces

Hosseini-Yazdi, S.-S.

10.1101/2024.07.08.602562 — bioengineering — Posted on 2024-07-11

3379 Body size and light environment modulate flight speed and saccadic behavior in free flying Drosophila melanogaster

Barredo, E.; Yang, H.; Currea, J. P.; Sondhi, Y.; Palavalli-Nettimi, R.; Sponberg, S.; Tarokh, V.; Theobald, J.

10.1101/2024.07.08.602594 — animal behavior and cognition — Posted on 2024-07-11

3380 Identifying foraging spatial cues in beehive sound activity using machine learning methods

Bocanegra, D.; Galvez, J.; Di, N.; Liu, F.; Wario, F.

10.1101/2024.07.08.602596 — animal behavior and cognition — Posted on 2024-07-11

3381 Dynamic alterations in gene co-expression networks and gene-transcript associations characterize co-morbidities in cocaine use disorder

Nwaneshiudu, C.; Girdhar, K.; Kleopoulos, S.; Fullard, J.; Butelman, E.; Parvaz, M.; Goldstein, R. Z.; Alia-Klein, N.; Roussos, P.

10.1101/2024.07.10.602908 — genomics — Posted on 2024-07-11

3382 Smooth muscle expression of RNA editing enzyme ADAR1 controls vascular integrity and progression of atherosclerosis

Weldy, C. S.; Li, Q.; Monteiro, J. P.; Guo, H.; Galls, D.; Gu, W.; Cheng, P. P.; Ramste, M.; Li, D. Y.; Palmisano, B. T.; Sharma, D.; Worssam, M. D.; Zhao, Q.; Bhate, A.; Kundu, R.; Nguyen, T.; Li, J. B.; Quertermous, T.

10.1101/2024.07.08.602569 — genomics — Posted on 2024-07-11

3383 Optically Mapped Black Genomes: Distinct Structures and 22q11.2 Deletion Syndrome Mechanisms

Pastor, S.; Tran, O.; Lapointe, R.; Olali, A. Z.; Wallace, D. C.; Morrow, B. E.; Zackai, E. H.; McDonald-McGinn, D. M.; Emanuel, B. S.

10.1101/2024.07.08.602568 — genomics — Posted on 2024-07-11

3384 Vcam1+ Fibro-adipogenic Progenitors Mark Fatty Infiltration in Chronic Limb Threatening Ischemia

Dai, Q.; Wan, C.; Xu, Y.; Fei, K.; Olivere, L. A.; Garrett, B.; Akers, L.; Peters, D.; Otto, J. C.; Kontos, C. D.; Ji, Z.; Diao, Y.; Southerland, K. W.

10.1101/2024.07.08.602430 — genomics — Posted on 2024-07-11

3385 Gut metagenomes of Asian octogenarians reveal metabolic potential expansion and distinct microbial species associated with aging phenotypes

Ravikrishnan, A.; Wijaya, I.; Png, E.; Chng, K. R.; Xin Pei, E. H.; Ng, H. Q. A.; Mohamed Naim, A. N.; Eric Emmanuel, J.-S.; Guan, S. P.; Lee, H. J.; Guan, L.; Li, C.; Koh, J. J. Y.; de Sessions, P. F.; Koh, W.-P.; Lei, F.; Ng, T. P.; Larbi, A.; Maier, A. B.; Kennedy, B.; Nagarajan, N.

10.1101/2024.07.08.602612 — genomics — Posted on 2024-07-11

3386 ANASFV: a workflow for ASFV whole genome sequencing, assembly, and evaluation

Li, K.; Han, X.; Shao, Y.; Zhao, X.; Johnson, E. W.; Li, R.

10.1101/2024.07.08.602471 — genetics — Posted on 2024-07-11

3387 Host-use Drives Convergent Evolution in Clownfish and Disentangles the Mystery of an Iconic Adaptive Radiation

Gaboriau, T. N.; Marcionetti, A.; Garcia Jimenez, A.; Schmid, S.; Fitzgerald, L. M.; Micheli, B.; Titus, B.; Salamin, N.

10.1101/2024.07.08.602550 — evolutionary biology — Posted on 2024-07-11

3388 Phylogenetic analysis reveals how selection and mutation shape the coevolution of mRNA and protein abundances

Cope, A. L.; Schraiber, J. G.; Pennell, M.

10.1101/2024.07.08.602411 — evolutionary biology — Posted on 2024-07-11

3389 Unifying (simple) models of genetic robustness and evolvability

Hardy, N. B.

10.1101/2024.07.08.602504 — evolutionary biology — Posted on 2024-07-11

3390 Global thermal tolerance of freshwater invertebrates and fish

Bayat, H. S.; He, F.; Madariaga, G. M.; Escobar-Sierra, C.; Prati, S.; Jupke, J. F.; Peters, K.; Chen, X.; Spaak, J. W.; Manfrin, A.; Juvigny-Khenafou, N. P. D.; Schäfer, R. B.

10.1101/2024.07.08.602306 — ecology — Posted on 2024-07-11

3391 Entangled and non-modular enhancer sequences producing independent spatial activities

Gompel, N.; Museridze, M.; Ceolin, S.; Muehling, B.; Ramanathan, S.; Barmina, O.; Santhi Sekhar, P.

10.1101/2024.07.08.602541 — developmental biology — Posted on 2024-07-11

3392 Mechanosensitive PIEZO2 channels shape coronary artery development

Pampols-Perez, M.; Fuerst, C.; Sanchez-Carranza, O.; Cano, E.; Raimundo, S.; Lindberg, E. L.; Taube, M.; Heuser, A.; Sporbert, A.; Huebner, N.; Gerhardt, H.; Lewin, G. R.; Hammes, A.

10.1101/2024.07.08.602502 — developmental biology — Posted on 2024-07-11

3393 Loss of the systemic vitamin A transporter RBPR2 affects the quantitative balance between chromophore and opsins in visual pigment synthesis

Radhakrishnan, R.; Leung, M.; Lor, A.; More, S.; Lobo, G. P.

10.1101/2024.07.08.602543 — cell biology — Posted on 2024-07-11

3394 Annexin A2 and lamin B join membrane recycling compartments for the assembly of biomolecular condensates operating in mitotic partitioning

Grindheim, A. K.; Dale, H. A.; Novak, J.; Patil, S. S.; Vedeler, A.; Saraste, J.

10.1101/2024.07.08.602477 — cell biology — Posted on 2024-07-11

3395 FLASH proton reirradiation, with or without hypofractionation, mitigates chronic toxicity in the normal murine intestine, skin, and bone.

Verginadis, I. I.; Velalopoulou, A.; Kim, M. M.; Kim, K.; Paraskevaidis, I.; Bell, B.; Oliaei Motlagh, S. A.; Karaj, A.; Banerjee, E.; Finesso, G. E.; Assenmacher, C.-A.; Radaelli, E.; Lu, J.; Lin, Y.; Putt, M. E.; Diffenderfer, E. S.; Guha, C.; Qin, L.; Metz, J. M.; Maity, A.; Cengel, K. A.; Koumenis, C.; Busch, T. M.

10.1101/2024.07.08.602528 — cell biology — Posted on 2024-07-11

3396 The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate

Marin, H.; Simental, E.; Allen, C.; Martin, E.; Panning, B.; Al-Sady, B.; Buchwalter, A.

10.1101/2024.07.08.602542 — cell biology — Posted on 2024-07-11

3397 Mitochondrial Fatty Acid Synthesis and Mecr Regulate CD4+ T Cell Function and Oxidative Metabolism

Steiner, K. K.; Young, A. C.; Patterson, A. R.; Jennings, E. Q.; Chi, C.; Hatem, Z.; Heintzman, D.; Sugiura, A.; Arner, E. N.; Sewell, A. E.; Madden, M. Z.; Okparaugo, R.; Fallman, E. V.; Gibson-Corley, K.; Voss, K.; Mogilenko, D.; Rathmell, J.

10.1101/2024.07.08.602554 — immunology — Posted on 2024-07-11

3398 A variational deep-learning approach to modeling memory T cell dynamics

van Dorp, C. H.; Gray, J. I.; Paik, D. H.; Farber, D. L.; Yates, A. J.

10.1101/2024.07.08.602409 — immunology — Posted on 2024-07-11

3399 Structural Mapping of Polyclonal IgG Responses to HA After Influenza Virus Vaccination or Infection

Leon, A. N.; Rodriguez, A. J.; Richey, S. T.; Torrents de la Pena, A.; Wolters, R. M.; Jackson, A. M.; Webb, K.; Creech, C. B.; Yoder, S.; Mudd, P. A.; Crowe, J. E.; Han, J.; Ward, A. B.

10.1101/2024.07.08.601940 — immunology — Posted on 2024-07-11

3400 Sex-dependent, lateralized engagement of anterior insular cortex inputs to the dorsolateral striatum in binge alcohol drinking

Haggerty, D. L.; Atwood, B.

10.1101/2023.08.23.554484 — neuroscience — Posted on 2024-07-11

3401 On the replicability of diffusion weighted MRI-based brain-behavior models

Kotikalapudi, R.; Kincses, B.; Gallitto, G.; Englert, R.; Hoffschlag, K.; Li, J.; Bingel, U.; Spisak, T.

10.1101/2024.07.08.602202 — neuroscience — Posted on 2024-07-11

3402 Behavioral and anatomical effects of complex rearing after day 7 neonatal frontal lesions vary with sex

Kolb, B.; Gibb, R.

10.1101/2024.07.08.602597 — neuroscience — Posted on 2024-07-11

3403 The Origin of Movement Biases During Reaching

Wang, T.; Morehead, R.; Tsay, J. S.; Ivry, R. B.

10.1101/2024.03.15.585272 — neuroscience — Posted on 2024-07-11

3404 Temporal resolution of spike coding in feedforward networks with signal convergence and divergence

Mobille, Z.; Sikandar, U. B.; Sponberg, S.; Choi, H.

10.1101/2024.07.08.602598 — neuroscience — Posted on 2024-07-11

3405 Prefrontal and ventral striatal dendritic morphology: effects of life-long complex housing and amphetamine administration

Kolb, B.; Robinson, T. E.

10.1101/2024.07.08.602601 — neuroscience — Posted on 2024-07-11

3406 Newly discovered base barrier cells provide compartmentalization of choroid plexus, brain and CSF

Verhaege, D.; De Nolf, C.; Castelein, J.; Claeys, W.; Van Wonterghem, E.; Van Imschoot, G.; Dujardin, P.; De Spiegelaere, W.; Hoste, E.; Boone, F.; Lidov, H. G.; Dani, N.; Derk, J.; Kremer, A.; Van Hamme, E.; Borghgraef, P.; Lippens, S.; Lehtinen, M. K.; Siegenthaler, J.; Van Hoecke, L.; Vandenbroucke, R. E.

10.1101/2024.07.08.601696 — neuroscience — Posted on 2024-07-11

3407 Spectral-switching analysis reveals real-time neuronal network representations of concurrent spontaneous naturalistic behaviors in human brain

Zhu, H.; Michalak, A. J.; Merricks, E. M.; Agopyan-Miu, A. H. C. W.; Jacobs, J.; Hamberger, M. J.; Sheth, S.; McKhann, G. M.; Feldstein, N.; Schevon, C.; Hillman, E. M. C.

10.1101/2024.07.08.600416 — neuroscience — Posted on 2024-07-11

3408 Mineral Phase Changes During Intervertebral Disc Degeneration

Yenen, T. B.; Jugdaohsingh, R.; Thom, W. D.; Khan, S.; Solano, V. R.; Lampronti, G. I.; Brown, A.; Saez, J.; Corbetta, D.; Eminaga, S.; Cherubini, G. B.; Powell, J.; Hughes, K.; Freeman, P.

10.1101/2024.07.08.602462 — neuroscience — Posted on 2024-07-11

3409 Detrimental Influence of Arginase-1 in Infiltrating Macrophages on Post-Stroke Functional Recovery and Inflammatory Milieu

Kim, H. S.; Jee, S. A.; Einisadr, A.; Seo, Y.; Seo, H. G.; Jang, B. S.; Park, H. H.; Chung, W.-S.; Kim, B. G.

10.1101/2024.07.08.602449 — neuroscience — Posted on 2024-07-11

3410 Dynamic control of neural manifolds

Lehr, A. B.; Kumar, A.; Tetzlaff, C.

10.1101/2024.07.08.602452 — neuroscience — Posted on 2024-07-11

3411 Translating human drug use patterns into rat models: exploring spontaneous interindividual differences via refined drug self-administration procedures

D'Ottavio, G.; Pezza, S.; Modoni, J.; Reverte, I.; Marchetti, C.; Zenoni, S. F.; Termine, A.; Fabrizio, C.; Maftei, D.; Lattanzi, R.; Esposito, G.; Ragozzino, D.; Merlo, E.; Milella, M. S.; Ciccocioppo, R.; Fumagalli, F.; Venniro, M.; Badiani, A.; Boix, F.; Caprioli, D.

10.1101/2024.07.08.602268 — neuroscience — Posted on 2024-07-11

3412 High-speed three-dimensional random access scanning with SPARCLS

Berlage, C.; Bohm, U. L.; Sanchez Moreno, A.; Ledderose, J.; Gidon, A.; Larkum, M. E.; Plested, A.; Judkewitz, B.

10.1101/2024.07.08.602445 — neuroscience — Posted on 2024-07-11

3413 Interoceptive Signals Bias Decision Making in Rhesus Macaques

Cardenas, M. A.; Le, R. P.; Champ, T. M.; O'Neill, D.; Fuglevand, A. J.; Gothard, K. M.

10.1101/2024.07.08.602563 — neuroscience — Posted on 2024-07-11

3414 Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens

Martinez-Rivera, F. J.; Yim, Y. Y.; Godino, A.; Minier-Toribio, A.; Tofani, S.; Holt, L. M.; Torres-Berrio, A.; Futamura, R.; Browne, C. J.; Markovic, T.; Hamilton, P. J.; Neve, R. L.; Nestler, E. J.

10.1101/2024.07.08.602609 — neuroscience — Posted on 2024-07-11

3415 A multi-region recurrent circuit for evidence accumulation in rats

Gupta, D.; Kopec, C. D.; Bondy, A. G.; Luo, T. Z.; Elliott, V. A.; Brody, C. D.

10.1101/2024.07.08.602544 — neuroscience — Posted on 2024-07-11

3416 Degradation in Binaural and Spatial Hearing and Auditory Temporal Processing Abilities as a Function of Aging

Sammeth, C. A.; Walker, K. A.; Greene, N. T.; Klug, A.; Tollin, D.

10.1101/2024.07.08.602575 — neuroscience — Posted on 2024-07-11

3417 Selective deletion of interleukin-1 alpha in microglia does not modify acute outcome but regulates neurorepair processes after experimental ischemic stroke.

Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Lenart, N.; Denes, A.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.

10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-07-11

3418 Aberrant remodelling of astrocytic architecture in acute hepatic encephalopathy: complexity of oedematic atrophic astrocytes

Popek, M. P.; Obara-Michlewska, M.; Szewczyk, L. M.; Kolodziej, M.; Verkhratsky, A.; Albrecht, J.; Zielinska, M.

10.1101/2024.07.08.602491 — neuroscience — Posted on 2024-07-11

3419 Development of a DSM test battery to determine depression-like marmoset

Yamanaka, H.; Ishibashi, H.; Nakamura, K.

10.1101/2024.07.08.602574 — neuroscience — Posted on 2024-07-11

3420 Co-activation of selective nicotinic acetylcholine receptor subtypes is required to reverse hippocampal network dysfunction and prevent fear memory loss in Alzheimer's disease

Lee, R.; Kim, G.; Kim, S.

10.1101/2024.07.08.602576 — neuroscience — Posted on 2024-07-11

3421 Multifunctional polymerization domains determine the onset of epigenetic silencing in Arabidopsis

Schulten, A.; Jang, G.-J.; Payne-Dwyer, A.; Nielsen, M. L.; Bienz, M.; Leake, M. C.; Dean, C.

10.1101/2024.02.15.580496 — plant biology — Posted on 2024-07-11

3422 Peripheral Skeletal Muscle Alterations in Adults Born Preterm: An Observational Comparative Study

Deprez, A.; El-Jalbout, R.; Cloutier, A.; Gagnon, D.; Gagnon Hamelin, A.; Mathieu, M.-E.; Arabi Kugathasan, T.; Dumont, N.; Nuyt, A. M.; Luu, T. M.

10.1101/2024.07.08.602584 — physiology — Posted on 2024-07-11

3423 Dietary fiber intervention modulates the formation of the cardiovascular risk factor trimethylamine-N-oxide after beef consumption

Haas, M.; Brandl, B.; Neuhaus, K.; Wudy, S.; Kleigrewe, K.; Hauner, H.; Skurk, T.

10.1101/2024.07.08.602621 — physiology — Posted on 2024-07-11

3424 Sonic hedgehog medulloblastoma cells in co-culture with cerebellar organoids converge towards in vivo malignant cell states

van Essen, M. J.; Nicheperovich, A.; Schuster-Boeckler, B.; Becker, E.; Jacob, J.

10.1101/2024.04.01.587603 — cancer biology — Posted on 2024-07-11

3425 Predicting immunotherapy response in advanced bladder cancer: a meta-analysis of six independent cohorts

Boll, L. M.; Vazquez Montes de Oca, S.; Camarena, M. E.; Castelo, R.; Bellmunt, J.; Perera-Bel, J.; Alba, M. M.

10.1101/2024.04.18.589711 — cancer biology — Posted on 2024-07-11

3426 Functional properties of a disease mutation for migraine in Kv2.1/6.4 channels

Tewari, D.; Sattler, C.; Benndorf, K.

10.1101/2024.07.08.602400 — biophysics — Posted on 2024-07-11

3427 Slow diffusion and signal amplification on membranes regulated by phospholipase D

Honda, G.; Tanaka, C.; Sawai, S.; Yanagisawa, M.

10.1101/2024.07.08.602473 — biophysics — Posted on 2024-07-11

3428 Parallel Sampling of Protein-Ligand Dynamics

Masters, M. R.; Mahmoud, A. H.; Lill, M. A.

10.1101/2024.07.08.602465 — biophysics — Posted on 2024-07-11

3429 Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries

Ling, Y. H.; Liang, C.; Wang, S.; Wu, C.

10.1101/2024.07.08.602478 — biophysics — Posted on 2024-07-11

3430 Hypersensitivity of the vimentin cytoskeleton to net-charge states and Coulomb repulsion

Unger, B.; Wu, C. Y.; Choi, A.; He, C.; Xu, K.

10.1101/2024.07.08.602555 — biophysics — Posted on 2024-07-11

3431 CryoJAM: Automating Protein Homolog Fitting in Medium Resolution Cryo-EM Density Maps

Carrion, J. T.; Manjrekar, M.; Mikulevica, A.

10.1101/2024.07.10.602952 — biophysics — Posted on 2024-07-11

3432 A look beyond topography: transient phenomena of Escherichia coli cell division captured with high-speed in-line force mapping

Ganser, C.; Nishiguchi, S.; Chan, F. Y.; Uchihashi, T.

10.1101/2024.07.08.602450 — biophysics — Posted on 2024-07-11

3433 Healthy microbiome - moving towards functional interpretation

Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Labaj, P. P.

10.1101/2023.12.04.569909 — bioinformatics — Posted on 2024-07-11

3434 Faster model-based estimation of ancestry proportions

Meisner, J.; Santander, C.; Refoyo Martinez, A.

10.1101/2024.07.08.602454 — bioinformatics — Posted on 2024-07-11

3435 Addressing the dynamic nature of reference data: a new nt database for robust metagenomic classification

Marti, J. M.; Kok, C. R.; Thissen, J. B.; Mulakken, N. J.; Avila-Herrera, A.; Jaing, C. J.; Allen, J. E.; Be, N. A.

10.1101/2024.06.12.598617 — bioinformatics — Posted on 2024-07-11

3436 Proteins Derived From MRL/MpJ Tendon Provisional Extracellular Matrix and Secretome Promote Pro-Regenerative Tenocyte Behavior

Marvin, J. C.; Liu, E. J.; Chen, H. H.; Shiovitz, D. A.; Andarawis-Puri, N.

10.1101/2024.07.08.602500 — bioengineering — Posted on 2024-07-11

3437 nP-collabs: Investigating counterion mediated bridges in the multiply phosphorylated tau-R2 repeat

Marien, J.; Prevost, C.; Sacquin-Mora, S.

10.1101/2024.04.18.590060 — biochemistry — Posted on 2024-07-11

3438 Observing one-divalent-metal-ion dependent and histidine-promoted His-Me family I-PpoI nuclease catalysis in crystallo

Chang, C.; Zhou, G.; Gao, Y.

10.1101/2024.05.02.592236 — biochemistry — Posted on 2024-07-11

3439 Quantifying the massive pleiotropy of microRNA: a human microRNA-disease causal association database generated with ChatGPT

Wang, K. R.; Hecker, J.; McGeachie, M. J.

10.1101/2024.07.08.602488 — genomics — Posted on 2024-07-11

3440 Loss of cped1 does not affect bone and lean mass in zebrafish

Alvarado, K.; Tang, W. J.; Watson, C. J.; Ahmed, A. R.; Gomez, A. E.; Donaka, R.; Amemiya, C. T.; Karasik, D.; Hsu, Y.-H.; Kwon, R. Y.

10.1101/2024.07.10.601974 — genetics — Posted on 2024-07-11

3441 Piwi mutant germ cells transmit a form of heritable stress that promotes longevity

Heestand, B.; McCarthy, B.; Simon, M.; Lister-Shimauchi, E. H.; Frenk, S.; Ahmed, S.

10.1101/326769 — genetics — Posted on 2024-07-11

3442 Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis Thaliana populations.

Gibbs, P.; Paril, J.; Fournier-Level, A.

10.1101/2024.07.09.601435 — genetics — Posted on 2024-07-11

3443 The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms

Li, X.; Marvaldi, A. E.; Oberprieler, R. G.; Clarke, D.; Farrell, B. D.; Sequeira, A.; Ferrer, M. S.; O'Brien, C.; Salzman, S.; Shin, S.; Tang, W.; McKenna, D. D.

10.1101/2024.03.12.584611 — evolutionary biology — Posted on 2024-07-11

3444 New groups of highly divergent proteins in families as old as cellular life with important biological functions in the ocean

Sussfeld, D.; Lannes, R.; Corel, E.; Bernard, G.; Martin, P.; Bapteste, E.; Pelletier, E.; Lopez, P.

10.1101/2024.01.08.574615 — evolutionary biology — Posted on 2024-07-11

3445 Evolutionary dynamics of genome structure and content among closely related bacteria

Molari, M.; Shaw, L. P.; Neher, R. A.

10.1101/2024.07.08.602537 — evolutionary biology — Posted on 2024-07-11

3446 Downscaling mutualistic networks from species to individuals reveals consistent interaction niches and roles within plant populations

Quintero, E.; Arroyo-Correa, B.; Isla, J.; Rodriguez-Sanchez, F.; Jordano, P.

10.1101/2024.02.02.578595 — ecology — Posted on 2024-07-11

3447 Population density drives increased parasitism via greater exposure and reduced resource availability in wild hosts

Hasik, A. Z.; Butt, S.; Turner, R. S.; Maris, K.; Morris, S.; Morris, A.; Pemberton, J. M.; Albery, G. F.

10.1101/2024.07.08.602460 — ecology — Posted on 2024-07-11

3448 Transient Naive Treatment (TNT) iPS cells do not feature Sendai virus expression: Response to Sendai virus persistence questions the transient naive reprogramming method for iPSC generation

Buckberry, S.; Liu, X.; Poppe, D.; Tan, J. P.; Faulkner, G. J.; Polo, J. M.; Lister, R.

10.1101/2024.07.10.602807 — developmental biology — Posted on 2024-07-11

3449 Growth patterns of caudal fin rays are informed by both external signals from the regenerating organ and remembered identity autonomous to the local tissue

Autumn, M.; Hu, Y.; Zeng, J.; McMenamin, S.

10.1101/2024.03.29.586899 — developmental biology — Posted on 2024-07-11

3450 Single cell profiling to determine influence of wheeze and early-life viral infection on developmental programming of airway epithelium

Berdnikovs, S.; Newcomb, D. C.; McKernan, K. E.; Kuehnle, S. N.; Haruna, N.-F.; Gebretsadik, T.; McKennan, C. G.; Ma, S.; Cephus, J.-Y.; Rosas-Salazar, C.; Anderson, L. J.; Gern, J. E.; Hartert, T.

10.1101/2024.07.08.602506 — developmental biology — Posted on 2024-07-11

3451 Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

Jo, K.; Liu, Z.-Y.; Patel, G.; Yu, Z.; Yao, L.; Teague, S.; Johnson, C.; Spence, J.; Heemskerk, I.

10.1101/2024.07.08.602611 — developmental biology — Posted on 2024-07-11

3452 Pan-flavivirus analysis reveals sfRNA-independent, 3'UTR-biased siRNA production from an Insect-Specific Flavivirus

Besson, B.; Overheul, G. J.; Wolfinger, M. T.; Junglen, S.; Van Rij, R. P.

10.1101/2022.08.18.504478 — microbiology — Posted on 2024-07-11

3453 Facultative endosymbiosis between cellulolytic protists and methanogenic archaea in the gut of the Formosan termite Coptotermes formosanus

Kaneko, M.; Omori, T.; Igai, K.; Mabuchi, T.; Sakai-Tazawa, M.; Nishihara, A.; Kihara, K.; Yoshimura, T.; Ohkuma, M.; Hongoh, Y.

10.1101/2024.05.03.592298 — microbiology — Posted on 2024-07-11

3454 A comprehensive two-hybrid analysis to explore the L. pneumophila effector-effector interactome

O'Connor Mount, H.; Urbanus, M. L.; Sheykhkarimli, D.; Cote, A. G.; Laval, F.; Coppin, G.; Kishore, N.; Li, R.; Spirohn-Fitzgerald, K.; Petersen, M. O.; Knapp, J. J.; Kim, D.-K.; Twizere, J.-C.; Calderwood, M. A.; Vidal, M.; Roth, F. P.; Ensminger, A. W.

10.1101/2024.03.29.587239 — microbiology — Posted on 2024-07-11

3455 Membrane binding properties of the cytoskeletal protein bactofilin

Liu, Y.; Karmakar, R.; Steinchen, W.; Mukherjee, S.; Bange, G.; Schafer, L. V.; Thanbichler, M.

10.1101/2024.06.14.599034 — microbiology — Posted on 2024-07-11

3456 Sleep and memory consolidation are linked by RNA processing genes in the Drosophila mushroom body

Li, Y.; Chouhan, N. S.; Zhang, S. L.; Moore, R. S.; Shon, J.; Noya, S. B.; Yue, Z.; Sehgal, A.

10.1101/2023.05.31.543136 — neuroscience — Posted on 2024-07-11

3457 Distributed representations of behavior-derived object dimensions in the human visual system

Contier, O.; Baker, C. I.; Hebart, M. N.

10.1101/2023.08.23.553812 — neuroscience — Posted on 2024-07-11

3458 No effect of additional education on long-term brain structure: a preregistered natural experiment in thousands of individuals.

Judd, N.; Kievit, R.

10.1101/2024.05.17.594682 — neuroscience — Posted on 2024-07-11

3459 Sensory encoding of emotion conveyed by the face and visual context

Soderberg, K.; Jang, G.; Kragel, P.

10.1101/2023.11.20.567556 — neuroscience — Posted on 2024-07-11

3460 Evidence for domain-general arousal from semantic and neuroimaging meta-analyses reconciles opposing views on arousal

Sabat, M.; de Dampierre, C.; Tallon-Baudry, C.

10.1101/2024.05.27.594944 — neuroscience — Posted on 2024-07-11

3461 A Myelin Map of Trunk Folds in the Elephant Trigeminal Nucleus

Reveyaz, N.; Schneeweiss, U.; Heise, O.; Gerhardt, B.; Gui, A. M.; Kaufmann, L. V.; Alfken, J.; Reichmann, J.; Salditt, T.; Hildebrandt, T. B.; Brecht, M.

10.1101/2023.11.15.567239 — neuroscience — Posted on 2024-07-11

3462 Automating clinical assessments of memory deficits: Deep Learning based scoring of the Rey-Osterrieth Complex Figure

Langer, N.; Weber, M.; Hebling Vieira, B.; Strzelczyk, D.; Wolf, L.; Pedroni, A.; Heitz, J.; Schultheis, C.; Troendle, M.; Arango Lasprilla, J. C.; Rivera, D.; Scarpina, F.; Zhao, Q.; Leuthold, R.; Wehrle, F.; Jenni, O. G.; Brugger, P.; Zaehle, T.; Lorenz, R.; Zhang, C.

10.1101/2022.06.15.496291 — neuroscience — Posted on 2024-07-11

3463 Male cuticular pheromones stimulate removal of the mating plug and promote re-mating through pC1 neurons in Drosophila females

Yun, M.; Kim, D.-H.; Ha, T. S.; Lee, K.-M.; Park, E.; Knaden, M.; Hansson, B. S.; Kim, Y.-J.

10.1101/2023.11.28.568981 — neuroscience — Posted on 2024-07-11

3464 Neural Prioritisation of Past Solutions Supports Generalisation

Hall-McMaster, S.; Tomov, M. S.; Gershman, S. J.; Schuck, N. W.

10.1101/2024.06.10.598294 — neuroscience — Posted on 2024-07-11

3465 Life Cycle and Morphogenetic Differentiation in Heteromorphic Cell Types of a Cosmopolitan Marine Microalga

Bousquet, L.; Fainsod, S.; Decelle, J.; Murik, O.; Chevalier, F.; Gallet, B.; Templin, R.; Schwab, Y.; Avrahami, Y.; Koplovitz, G.; Ku, C.; Frada, M.

10.1101/2024.07.03.601694 — plant biology — Posted on 2024-07-11

3466 Deep phenotyping of the prostate tumor microenvironment reveals molecular stratifiers of relapse and links inflammatory chemokine expression to aberrant metabolism

Krossa, S.; Andersen, M. K.; Midtbust, E.; Wess, M.; Kiviaho, A.; Sharma, A.; Viset, T.; Storkersen, O.; Giskeodegard, G. F.; Nykter, M.; Urbanucci, A.; Rye, M. B.; Tessem, M.-B.

10.1101/2024.05.13.593822 — cancer biology — Posted on 2024-07-11

3467 Resolving atomic-level dynamics and interactions of high-molecular weight hyaluronic acid by multidimensional solid-state NMR

Rampratap, P.; Lasorsa, A.; Arunachalam, A.; Kamperman, M.; Walvoort, M. T. C.; van der Wel, P. C. A.

10.1101/2024.02.29.582163 — biophysics — Posted on 2024-07-11

3468 Sizes, conformational fluctuations, and SAXS profiles for Intrinsically Disordered Proteins

Mugnai, M. L.; Chakraborty, D.; Kumar, A.; Nguyen, H. T.; Zeno, W.; Stachowiak, J. C.; Straub, J. E.; Thirumalai, D.

10.1101/2023.04.24.538147 — biophysics — Posted on 2024-07-11

3469 Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response

Huang, H.-C.; Nowak, I.; Lobo, V.; Besavilla, D. F.; Schon, K.; Westholm, J. O.; Fernandez, C.; Patel, A. A.; Wiel, C.; Sayin, V. I.; Anastasakis, D. G.; Angeletti, D.; Sarshad, A. A.

10.1101/2024.03.07.583365 — biochemistry — Posted on 2024-07-11

3470 The Open Pediatric Cancer Project

Geng, Z.; Wafula, E.; Corbett, R. J.; Zhang, Y.; Jin, R.; Gaonkar, K. S.; Shukla, S.; Rathi, K. S.; Hill, D.; Lahiri, A.; Miller, D. P.; Sickler, A.; Keith, K.; Blackden, C.; Chroni, A.; Brown, M. A.; Kraya, A. A.; Koschmann, C. J.; Aldape, K.; Huang, X.; Rood, B. R.; Mason, J. L.; Trooskin, G. R.; Abdullaev, Z.; Wang, P.; Zhu, Y.; Farrow, B. K.; Farrel, A.; Dybas, J. M.; Zhong, C.; Van Kuren, N.; Zhang, B.; Santi, M.; Phul, S.; Chinwalla, A. T.; Resnick, A. C.; Diskin, S. J.; Tasian, S.; Stefankiewicz, S.; Maris, J. M.; Ennis, B. M.; Lueder, M. R.; Naqvi, A. S.; Coleman, N.; Ma, W.; Taylor, D

10.1101/2024.07.09.599086 — genomics — Posted on 2024-07-11

3471 Dissecting genetic correlation and pleiotropy through a genetic cross

Cai, H.; Geiler-Samerotte, K.; Des Marais, D. L.

10.1101/2023.05.12.540583 — evolutionary biology — Posted on 2024-07-11

3472 Diversification and recurrent adaptation of the synaptonemal complex in Drosophila

Zakerzade, R.; Chang, C.-H.; Chatla, K.; Krishnapura, A.; Appiah, S. P.; Zhang, J.; Unckless, R. L.; Blumenstiel, J.; Bachtrog, D.; Wei, K. H.

10.1101/2023.10.20.563324 — evolutionary biology — Posted on 2024-07-11

3473 Cardiomyocyte antisense transcription regulates exon usage in the elastic spring region of Titin to modulate sarcomere function

Celik, S.; Hyrefelt, L.; Czuba, T.; Li, Y.; Assis, J.; Andre, O.; Sandstedt, J.; Nordenfelt, P.; Vukusic, K.; Smith, J. G.; Gidlof, O.

10.1101/2024.07.10.602998 — molecular biology — Posted on 2024-07-11

3474 A platform for lab management, note-keeping and automation

Fleiss, A.; Mishin, A. S.; Sarkisyan, K. S.

10.1101/2024.07.08.602487 — molecular biology — Posted on 2024-07-11

3475 Endogenous ZAP is associated with altered global cellular gene expression during Zika virus infection

Le, N. P. K.; Singh, P. P.; Sabir, A. J.; Trus, I.; Karniychuk, U.

10.1101/2024.05.23.595518 — microbiology — Posted on 2024-07-11

3476 Impacts of Antiretroviral Therapy on the Oral Microbiome and Periodontal Health of Feline Immunodeficiency Virus Positive Cats

Bashor, L.; Rawlinson, J. E.; Kozakiewicz, C. P.; Behzadi, E.; Miller, C.; Kim, J.; Conry, M.; Nehring, M.; Carver, S.; Abdo, Z.; VandeWoude, S.

10.1101/2024.07.10.602918 — microbiology — Posted on 2024-07-11

3477 Objective Markers of Sustained Attention Fluctuate Independently of Mind-Wandering Reports

Chidharom, M.; Bonnefond, A.; Vogel, E. K.; Rosenberg, M. D.

10.1101/2024.07.08.602532 — neuroscience — Posted on 2024-07-11

3478 Brief targeting of resurgent STAT3 activation in chronic epilepsy for potent and enduring disease modification.

Hoffman, O. R.; Koehler, J. L.; Espina, J. E. C.; Patterson, A.; Gohar, E.; Coleman, E.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.

10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-07-11

3479 A cancer immunotherapy modality based on dendritic cell reprogramming in vivo

Ascic, E.; Akerstrom, F.; Sreekumar Nair, M.; Rosa, A.; Kurochkin, I.; Zimmermannova, O.; Catena, X.; Rotankova, N.; Veser, C.; Rudnik, M.; Ballocci, T.; Scharer, T.; Huang, X.; de Rosa Torres, M.; Renaud, E.; Velasco Santiago, M.; Met, O.; Askmyr, D.; Lindstedt, M.; Greiff, L.; Ligeon, L.-A.; Agarkova, I.; Svane, I. M.; F. Pires, C.; F. Rosa, F.; Pereira, C.-F.

10.1101/2024.07.08.602356 — immunology — Posted on 2024-07-11

3480 Spatial and mechanical environments regulate the heterogeneity of myonuclei

NICOLAS, R.; BLAVET, c.; BONNIN, M.-A.; ESTEVES DE LIMA, J.; LEGALLAIS, C.; DUPREZ, D.

10.1101/2024.07.08.602510 — developmental biology — Posted on 2024-07-11

3481 FtsN coordinates septal peptidoglycan synthesis and degradation through self-interaction of SPOR in E. coli

Lyu, Z.; Yang, X.; Yahashiri, A.; Ha, S.; McCausland, J. W.; Chen, X.; Britton, B. M.; Weiss, D. S.; Xiao, J.

10.1101/2024.05.13.594014 — microbiology — Posted on 2024-07-11

3482 Generating serum-based antibodies from tumor-exposed mice: a new potential strategy for cutaneous squamous cell carcinoma treatment

Liu, Z.

10.1101/2023.07.26.550693 — cancer biology — Posted on 2024-07-11

3483 Impacts of pleiotropy and migration on repeated genetic adaptation

Battlay, P.; Yeaman, S.; Hodgins, K.

10.1101/2021.09.13.459985 — genetics — Posted on 2024-07-11

3484 Minimal background noise enhances neural speech tracking: Evidence of stochastic resonance

Herrmann, B.

10.1101/2024.06.19.599692 — neuroscience — Posted on 2024-07-11

3485 A coarse-grained model for disordered and multi-domain proteins

Cao, F.; von Bülow, S.; Tesei, G.; Lindorff-Larsen, K.

10.1101/2024.02.03.578735 — biophysics — Posted on 2024-07-11

3486 Biomolecular condensates can function as inherent catalysts

Guo, X.; Farag, M.; Qian, N.; Yu, X.; Ni, A.; Ma, Y.; Yu, W.; King, M.; Liu, V.; Lee, J.; Min, W.; Zare, R. N.; Pappu, R. V.; Dai, Y.

10.1101/2024.07.06.602359 — biophysics — Posted on 2024-07-11

3487 Optimization of an adeno-associated viral vector for epidermal keratinocytes in vitro and in vivo

Shen, Q.; Suga, S.; Moriwaki, Y.; Zening, D.; Aizawa, E.; Okazaki, M.; Izpisua Belmonte, J. C.; Hirabayashi, Y.; Suzuki, K.; Kurita, M.

10.1101/2024.04.15.589645 — bioengineering — Posted on 2024-07-11

3488 A unique cell division protein critical for the assembly of the bacterial divisome

Chu, X.; Wang, L.; Zhu, Y.; Feng, Z.; Guan, Q.; Song, L.; Luo, Z.

10.1101/2023.04.24.538182 — biochemistry — Posted on 2024-07-11

3489 Impaired motor-to-sensory transformation mediates auditory hallucinations

Yang, F.; Zhu, H.; Cao, X.; Li, H.; Fang, X.; Yu, L.; Li, S.; Wu, Z.; Li, C.; Zhang, C.; Tian, X.

10.1101/2023.06.10.544451 — neuroscience — Posted on 2024-07-11

3490 GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis

Bisson, J. A.; Gordillo, M.; Kumar, R.; de Silva, N.; Yang, E.; Banks, K. M.; Shi, Z.-D.; Lee, K.; Yang, D.; Chung, W. K.; Huangfu, D.; Evans, T.

10.1101/2024.07.09.602666 — developmental biology — Posted on 2024-07-11

3491 A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing

Hwang, J. K.; Marston, D. J.; Wrapp, D.; Li, D.; Tuyishime, M.; Brackenridge, S.; Rhodes, B.; Quastel, M.; Kapingidza, A. B.; Gater, J.; Harner, A.; Wang, Y.; Rountree, W.; Ferrari, G.; Borrow, P.; McMichael, A. J.; Gillespie, G. M.; Haynes, B. F.; Azoitei, M. L.

10.1101/2024.07.08.602401 — immunology — Posted on 2024-07-11

3492 Local genetic adaptation to habitat in wild chimpanzees

Ostridge, H. J.; Fontsere, C.; Lizano, E.; Soto, D. C.; Schmidt, J. M.; Saxena, V.; Alvarez-Estape, M.; Barratt, C. D.; Gratton, P.; Bocksberger, G.; Lester, J. D.; Dieguez, P.; Agbor, A.; Angedakin, S.; Assumang, A. K.; Bailey, E.; Barubiyo, D.; Bessone, M.; Brazzola, G.; Chancellor, R.; Cohen, H.; Coupland, C.; Danquah, E.; Deschner, T.; Dotras, L.; Dupain, J.; Egbe, V. E.; Granjon, A.-C.; Head, J.; Hedwig, D.; Hermans, V.; Hernandez-Aguilar, R. A.; Jeffery, K. J.; Jones, S.; Junker, J.; Kadam, P.; Kaiser, M.; Kalan, A. K.; Kambere, M.; Kienast, I.; Kujirakwinja, D.; Langergraber, K. E.; Lap

10.1101/2024.07.09.601734 — evolutionary biology — Posted on 2024-07-11

3493 Trait genetic architecture and population structure determine model selection for genomic prediction in natural Arabidopsis Thaliana populations.

Gibbs, P.; Paril, J.; Fournier-Level, A.

10.1101/2024.07.09.601435 — genetics — Posted on 2024-07-11

3494 Hippocampal-prefrontal communication subspaces align with behavioral and network patterns in a spatial memory task

Young, R. A.; Shin, J. D.; Guo, Z.; Jadhav, S. P.

10.1101/2024.07.08.601617 — neuroscience — Posted on 2024-07-11

3495 Elucidating Interactome Dynamics of the A2A Adenosine Receptor

Lee, W.; Son, A.; Kim, W.; Park, J.; Cho, J.-y.; Kim, J.-W.; Kim, Y.-O.; Kong, H. J.; Kim, H.

10.1101/2024.07.08.601789 — systems biology — Posted on 2024-07-11

3496 Elucidating the Type 2 Diabetes Regulatory Network: Identification of EGFR as a Key Hub and Novel Drug Candidates

Romero, R.; Cohen, C. A.

10.1101/2024.07.08.602441 — bioinformatics — Posted on 2024-07-11

3497 Unveiling Clonal Cell Fate and Differentiation Dynamics: A Hybrid NeuralODE-Gillespie Approach

Gao, M.; Barile, M.; Chabra, S.; Haltalli, M.; Calderbank, E.; Chao, Y.; Laurenti, E.; Gottgens, B.; Huang, Y.

10.1101/2024.07.08.602444 — bioinformatics — Posted on 2024-07-11

3498 Maternal obesity and offspring neurodevelopment are associated with hypoxic gene expression in term human placenta

Gunter-Rahman, F.; Mallett, S.; White, F.; Jacques, P.-E.; Raju, R. M.; Hivert, M.-F.; Lee, E. A.

10.1101/2024.07.10.602900 — genomics — Posted on 2024-07-10

3499 Structural constraints and drivers of molecular evolution in a macromolecular complex; the kinetochore

Pare, H. K.; Nguyen, A. L.; Pankey, S.; Cheeseman, I. M.; Plachetzki, D. C.

10.1101/2024.07.10.602950 — evolutionary biology — Posted on 2024-07-10

3500 Beyond brain size: disentangling the effect of sex and brain size on brain morphometry and cognitive functioning

Brzezinski-Rittner, A.; Moqadam, R.; Iturria-Medina, Y.; Chakravarty, M.; Dadar, M.; Zeighami, Y.

10.1101/2024.06.20.599908 — neuroscience — Posted on 2024-07-10

3501 Golgi cells regulate timing and variability of information transfer in a cerebellar-behavioural loop

Palacios, E. R.; Houghton, C. J.; Chadderton, P.

10.1101/2024.07.10.602852 — neuroscience — Posted on 2024-07-10

3502 Cerebellar contribution to cognitive deficits and prefrontal cortex dysfunction in Spinocerebellar Ataxia Type 1 (SCA1)

Sbrocco, K.; Borgenheimer, E.; Zhang, Y.; Koob, M.; Cvetanovic, M.

10.1101/2024.07.10.602931 — neuroscience — Posted on 2024-07-10

3503 Striatal endocannabinoid-long-term potentiation mediates one-shot learning

Piette, C.; Hubert, A.; Perez, S.; Berry, H.; Touboul, J. D.; Venance, L.

10.1101/2024.07.10.602953 — neuroscience — Posted on 2024-07-10

3504 Functional ultrasound imaging and neuronal activity: how accurate is the spatiotemporal match?

Lambert, T.; Niknejad, H. R.; Kil, D.; Brunner, C.; Nuttin, B.; Montaldo, G.; Urban, A.

10.1101/2024.07.10.602912 — neuroscience — Posted on 2024-07-10

3505 Neuronal Hyperactivity in Neurons Derived from Individuals with Grey Matter Heterotopia

Di Matteo, F.; Bonrath, R.; Schmidt, H.; Ayo Martin, A. C.; Pravata, V.; Di Giaimo, R.; Menegaz, D.; Riesenberg, S.; de Vrij, F. M. S.; Maccarrone, G.; Holzapfel, M.; Straub, T.; Kushner, S. A.; Robertson, S. P.; Matthias Eder, M.; Cappello, S.

10.1101/2024.07.10.602948 — neuroscience — Posted on 2024-07-10

3506 Developmental dynamics of the prefrontal cortical SST and PV interneuron networks: Insights from the monkey highlight human-specific features

Hosseini Fin, N. S.; Yip, A.; Teo, L.; Homman-Ludiye, J.; Bourne, J. A.

10.1101/2024.07.10.602904 — neuroscience — Posted on 2024-07-10

3507 Transcriptome signatures of the medial prefrontal cortex underlying GABAergic control of resilience to chronic stress exposure

Luscher, B.; Shao, M.; Botvinov, J.; Banerjee, D.; Girirajan, S.

10.1101/2024.07.10.602959 — neuroscience — Posted on 2024-07-10

3508 Multivariate analysis of metabolic state vulnerabilities across diverse cancer contexts reveals synthetically lethal associations

Abecunas, C.; Kidd, A. D.; Jiang, Y.; Zong, H.; Fallahi-Sichani, M.

10.1101/2023.11.28.569098 — cancer biology — Posted on 2024-07-10

3509 Molecular bases and specificity behind the activation of the immune system OAS/RNAse L pathway by viral RNA.

Jung-Rodriguez, E.; Barbault, F.; Bignon, E.; MONARI, A.

10.1101/2024.07.08.602453 — biophysics — Posted on 2024-07-10

3510 Separation of sticker-spacer energetics governs the coalescence of metastable biomolecular condensates

Chattaraj, A.; Shakhnovich, E. I.

10.1101/2023.10.03.560747 — biophysics — Posted on 2024-07-10

3511 Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy

Dave, K. M.; Venna, V. R.; Rao, K. S.; Stolz, D. B.; Brady, B.; Quaicoe, V. A.; Maniskas, M.; Hildebrand, E. E.; Green, D.; Chen, M.; Milosevic, J.; Zheng, S.-y.; Shiva, S.; McCullough, L. D.; Manickam, D. S.

10.1101/2024.01.16.575903 — bioengineering — Posted on 2024-07-10

3512 Comparative genomics reveals diversity and taxonomic relationships among Clostridioides difficile phages

Mondal, S. I.; Rolin, M. H.; Karim, D.; Jewel, N. A.; Khan, T.; Rahman, M.; Akter, A.

10.1101/2024.07.10.602917 — genomics — Posted on 2024-07-10

3513 Deletion of an evolutionarily conserved TAD boundary compromises spermatogenesis in mice

Lima, A. C.; Okhovat, M.; Stendahl, A. M.; VanCampen, J.; Nevonen, K. A.; Herrera, J.; Li, W.; Harshman, L.; Yang, R.; Fedorov, L.; Vigh-Conrad, K.; Ahituv, N.; Conrad, D.; Carbone, L.

10.1101/2024.07.08.602428 — genetics — Posted on 2024-07-10

3514 Mapping the Global Distribution of Mus musculus: Implications for Evolutionary Genetics

Garretson, A. C.; Blanco-Berdugo, L. A.; Dumont, B. L.

10.1101/2024.07.09.602589 — evolutionary biology — Posted on 2024-07-10

3515 Vestigial like 4 regulates the adipogenesis of classical brown adipose tissue

Zhou, P.; Kessinger, C. W.; Gu, F.; Davenport, A.; Wang, G.; Deplancke, B.; Pu, W. T.; Lin, Z.

10.1101/2024.07.09.602788 — developmental biology — Posted on 2024-07-10

3516 Single Cell Transcriptomics-informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage

Papalamprou, A.; Yu, V.; Jiang, W.; Sheyn, J.; Stefanovic, T.; Chen, A.; Castaneda, C.; Chavez, M.; Sheyn, D.

10.1101/2023.04.10.536240 — developmental biology — Posted on 2024-07-10

3517 Newborn reactions to maternal prenatal stress alter umbilical cord blood tRNA fragments targeting cholinergic transcripts

Vaknine Treidel, S.; Lobmaier, S.; Sharma, R.; Madrer, N.; Shulman, D.; Greenberg, P.; Bennett, E. R.; Greenberg, D. S.; Zelgert, C.; Zimmermann, P.; Frasch, M. G.; Carmel, L.; Antonelli, M. C.; Soreq, H.

10.1101/2024.07.10.602894 — molecular biology — Posted on 2024-07-10

3518 TDP-43 mutations-induced defects in miRNA biogenesis and cytotoxicity by differentially obstructing Dicer activity in Drosophila and in vitro

Meng, H.; Long, X.; Jiang, M.; Miao, Y.; Du, H.; Zhang, T.; Ma, Z.; Li, J.; Liu, C.

10.1101/2024.07.10.602849 — molecular biology — Posted on 2024-07-10

3519 In vivo tests of the E. coli TonB system working model:interaction of ExbB with unknown proteins, identification of TonB-ExbD transmembrane heterodimers and PMF-dependent ExbD structures.

Postle, K.; Kopp, D.; Jana, B.

10.1101/2024.07.10.602958 — molecular biology — Posted on 2024-07-10

3520 A porcine chronic hepatitis E virus (HEV) infection model exhibits HEV replication in male accessory reproductive glands and immune-mediated reproductive damage

Yadav, K. K.; Boley, P. A.; Laocharoensuk, T.; Khatiwada, S.; Lee, C. M.; Bhandari, M.; Hanson, J.; Kenney, S. P.

10.1101/2024.07.10.602840 — microbiology — Posted on 2024-07-10

3521 QuickFit: A high-throughput RT-qPCR-based assay to quantify viral growth and fitness in vitro

Galvez, N. M. S.; Sheehan, M. L.; Lin, A. Z.; Cao, Y.; Lam, E. C.; Jackson, A. M.; Balazs, A. B.

10.1101/2024.07.08.602587 — microbiology — Posted on 2024-07-10

3522 A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: unveiling a novel virulence factor

Volkening, J. D.; Spatz, S. J.; Garcia, M.; Zamora, A. C.; Rosenthal, K. S.; Skipper, A.; Blakey, J.; Ross, T. A.

10.1101/2024.07.10.602945 — microbiology — Posted on 2024-07-10

3523 Reconstruction and identification of the native PLP synthase complex from Methanosarcina acetivorans lysate

Agnew, A.; Humm, E.; Zhou, K.; Gunsalus, R. P.; Zhou, Z. H.

10.1101/2024.07.09.602819 — microbiology — Posted on 2024-07-10

3524 Proton-pump inhibitors increase C. difficile infection risk by altering pH rather than by affecting the gut microbiome based on a bioreactor model

Schumacher, J.; Mueller, P.; Sulzer, J.; Faber, F.; Molitor, B.; Maier, L.

10.1101/2024.07.10.602898 — microbiology — Posted on 2024-07-10

3525 Dynamics of bacterial biofilm development imaged using light sheet fluorescence microscopy

Smerdova, L.; Fuzik, T.; Valentova, L.; Bardy, P.; Prochazkova, M.; Parenicova, M.; Plevka, P.

10.1101/2024.07.10.602771 — microbiology — Posted on 2024-07-10

3526 Environmental differences impact Acinetobacter baumannii phage isolation and infectivity

Alseth, E. O.; Roush, C.; Irby, I.; Kopylov, M.; Bobe, D.; Nguyen, K.; Xu, H.; Bryksin, A. V.; Rather, P. N.

10.1101/2024.07.10.602838 — microbiology — Posted on 2024-07-10

3527 Engineering programmable CAR-T cells with tunable controls as fail-safe mechanisms during cancer immunotherapy

Dogan, M.; Kozhaya, L.; Placek, L.; Karhan, E.; Yigit, M.; Mohammed, C.; Zhao, Q.; Unutmaz, D.

10.1101/2024.07.09.602762 — immunology — Posted on 2024-07-10

3528 Mobius Assembly for Plant Systems uncovers combinatorial interactions among promoters, coding sequences, and terminators in gene regulation

Kocaoglan, E. G.; Andreou, A.; Nirkko, J.; Ochoa-Villarreal, M.; Loake, G.; Nakayama, N.

10.1101/2024.07.10.602858 — synthetic biology — Posted on 2024-07-10

3529 Atomistic Prediction of Structures, Conformational Ensembles and Binding Energetics for the SARS-CoV-2 Spike JN.1, KP.2 and KP.3 Variants Using AlphaFold2 and Molecular Dynamics Simulations: Mutational Profiling and Binding Free Energy Analysis Reveal Epistatic Hotspots of the ACE2 Affinity and Immune Escape

Raisinghani, N.; Alshahrani, M.; Gupta, G.; Verkhivker, G.

10.1101/2024.07.09.602810 — biophysics — Posted on 2024-07-10

3530 NMR Reveals the Synergistic Roles of Bivalent Metal Ions in Norovirus Infections

Maass, T.; Westermann, L. T.; Sharotri, L.; Blankenhorn, L.; Lane, M. S.; Chaika, M.; Taube, S.; Peters, T.; Mallagaray, A.

10.1101/2024.07.10.602906 — biochemistry — Posted on 2024-07-10

3531 The structural and biophysical basis of substrate binding to the hydrophobic groove in Ubiquilin Sti1 domains

Onwunma, J.; Binsabaan, S.; Allen, S. P.; Sankaran, B.; Wohlever, M. L.

10.1101/2024.07.10.602902 — biochemistry — Posted on 2024-07-10

3532 Modulating immune cell fate and inflammation through CRISPR-mediated DNA methylation editing

Valcarcel, G.; Lopez-Rubio, A. V.; Lazarenkov, A.; Berenguer, C.; Calafell, J.; Rodriguez-Ubreva, J.; Ballestar, E.; Sardina, J. L.

10.1101/2024.07.10.599183 — genomics — Posted on 2024-07-10

3533 Post-transcriptional cross- and auto-regulation buffer expression of the human RNA helicases DDX3X and DDX3Y

Rengarajan, S.; Derks, J.; Bellott, D. W.; Slavov, N.; Page, D. C.

10.1101/2024.07.08.602613 — genetics — Posted on 2024-07-10

3534 50 years of antibody numbering schemes: a statistical and structural evaluation reveals key differences and limitations

Zhu, Z.; Olson, K.; Magliery, T.

10.1101/2024.07.08.602590 — molecular biology — Posted on 2024-07-10

3535 Importin alpha inhibitors act against the differentiated stages of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii

Bhambid, M.; Walunj, S. B.; C.A., A.; Jain, S.; Mehta, D.; Wagstaff, K.; Panda, A.; Jans, D.; Mohmmed, A.; Patankar, S.

10.1101/2024.07.10.602875 — molecular biology — Posted on 2024-07-10

3536 A unique mechanism of snRNP core assembly

Wang, Y.; Chen, X.; Kong, X.; Chen, Y.; Xiang, Z.; Xiang, Y.; Hu, Y.; Hou, Y.; Zhou, S.; Shen, C.; Mu, L.; Su, D.; Zhang, R.

10.1101/2024.07.09.602679 — molecular biology — Posted on 2024-07-10

3537 A Transfection-Free Approach of Gene Editing via a gold-based nanoformulation of the Cas9 protein

Konstantinidou, S.; Lindstaedt, A.; Schmidt, T. J. N.; Nocilla, F.; Maltinti, G.; Rocco, M. A.; Landi, E.; De Carli, A.; Crucitta, S.; Lai, M.; Pistello, M.; Cappello, V.; Witt, D.; Gabellini, C.; Barski, P.; Raffa, V.

10.1101/2024.07.09.602746 — molecular biology — Posted on 2024-07-10

3538 Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits

10.1101/2024.07.10.602881 — molecular biology — Posted on 2024-07-10

3539 Temperate bacteriophage induced in Pseudomonas aeruginosa biofilms can modulate bacteriophage and antibiotic resistance

Martinet, M. G.; Samuel, B. J.; Weiss, D.; Pletz, M. W.; Makarewicz, O.

10.1101/2024.07.10.602839 — microbiology — Posted on 2024-07-10

3540 Evolutionary and functional divergence of Sfx, a plasmid-encoded H-NS homolog, underlies the regulation of IncX plasmid conjugation

Wang, A. L.; Cordova, M.; Navarre, W. W.

10.1101/2024.07.10.602937 — microbiology — Posted on 2024-07-10

3541 Star-polymers as potent broad-spectrum extracellular virucidal antivirals

Super, E. H.; Lai, S. M.; Cytlak-Chaudhuri, U.; Coppola, F.; Saouaf, O. M.; Song, Y. E.; Casey, K. M.; Batt, L. J.; Macleod, S.-L.; Bagley, R. H. T.; Korb, Z.; Kral, P.; Appel, E.; Travis, M.; Jones, S. T.

10.1101/2024.07.10.602907 — microbiology — Posted on 2024-07-10

3542 Pleiotropic regulation of bacterial toxin production and Allee effect govern microbial predator-prey interactions

Suma, H. R.; Stallforth, P.

10.1101/2024.07.10.602915 — microbiology — Posted on 2024-07-10

3543 N-acylethanolamine acid amidase inhibition reduces SARS-CoV-2 infection in Human Precision cut-lung slices and downregulates NF-kappaB signalling.

La Rocca, V.; Filipponi, C.; Diesendorf, V.; De Carli, A.; Sciandrone, G.; Nottoli, S.; Plicanti, E.; Fonnesu, R.; Iacono, E.; Mengozzi, A.; Masi, S.; Lenzi, P.; Fornai, F.; Sewald, K.; Obernolte, H.; Bodem, J.; Freer, G.; Pistello, M.; Lai, M.

10.1101/2024.07.10.602842 — microbiology — Posted on 2024-07-10

3544 Polysaccharide quantification using microbial enzyme cocktails

Pontrelli, S.; Sauer, U.

10.1101/2024.07.10.602880 — microbiology — Posted on 2024-07-10

3545 Omicron-specific ultra-potent SARS-CoV-2 neutralizing antibodies targeting the N1/N2 loop of Spike N-terminal domain

Niu, X.; Li, Z.; Wang, J.; Jian, F.; Yu, Y.; Song, W.; Yisimayi, A.; Du, S.; Zhang, Z.; Wang, Q.; Wang, J.; An, R.; Wang, Y.; Wang, P.; Sun, H.; Yu, L.; Yang, S.; Xiao, T.; Gu, Q.; Shao, F.; Wang, Y.; Xiao, J.; Cao, Y.

10.1101/2024.07.10.602843 — immunology — Posted on 2024-07-10

3546 Global siRNA Screen Reveals Critical Human Host Factors of SARS-CoV-2 Multicycle Replication

Yin, X.; Pu, Y.; Yuan, S.; Pache, L.; Churas, C.; Weston, S.; Riva, L.; Simons, L. M.; Cisneros, W.; Clausen, T.; de Jesus, P.; Kim, H. N.; Fuentes, D.; Whitelock, J.; Esko, J.; Lord, M.; Mena, I.; Garcia-Sastre, A.; Hultquist, J.; Frieman, M.; Ideker, T.; Pratt, D.; Martin-Sancho, L.; Chanda, S.

10.1101/2024.07.10.602835 — systems biology — Posted on 2024-07-10

3547 Genome assembly of a diversity panel of Chenopodium quinoa

Rey, E.; Abrouk, M.; Dufau, I.; Rodde, N.; Saber, N.; Cizkova, J.; Fiene, G.; Stanschewski, C.; Jarvis, D. E.; Jellen, E. N.; Maughan, P. J.; von Baer, I.; Troukhan, M.; Kravchuk, M.; Hribova, E.; Cauet, S.; Krattinger, S.; Tester, M. A.

10.1101/2024.07.07.602379 — genomics — Posted on 2024-07-10

3548 VISUALIZING GAUSSIAN-CHAIN LIKE STRUCTURAL MODELS OF HUMAN alpha-SYNUCLEIN IN MONOMERIC PRE-FIBRILLAR STATE: SOLUTION SAXS DATA AND MODELING ANALYSIS

SHARMA, D.; GANGULY, A.; DEY, M.; GUPTA, A.; BADMALIA, M. D.

10.1101/2024.07.07.602212 — biophysics — Posted on 2024-07-10

3549 Characterization of eight new Hydractinia i-cell markers reveals underlying heterogeneity in the adult pluripotent stem cell population

Waletich, J.; de Jong, D.; Schnitzler, C.

10.1101/2024.07.07.602406 — evolutionary biology — Posted on 2024-07-10

3550 Neural correlates of phenomenological attitude toward perceptual experience

Nishida, S.; Hamada, H. T.; Niikawa, T.; Miyahara, K.

10.1101/2024.07.07.602347 — neuroscience — Posted on 2024-07-10

3551 Hotspot of Exotic Benthic Marine Invertebrates Discovered in the Tropical East Atlantic: DNA Barcoding Insights from the Bijagos Archipelago, Guinea-Bissau

Moura, C. J.; Wirtz, P.; Nhanque, F. T.; Barbosa, C.; Serrao, E. A.

10.1101/2024.07.07.602388 — zoology — Posted on 2024-07-10

3552 Molecular dynamics investigation of the influenza hemagglutinin conformational changes in acidic pH

Badiee, S. A.; Govind Kumar, V.; Moradi, M.

10.1101/2024.07.07.602399 — biophysics — Posted on 2024-07-10

3553 Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform

Kuo, Y.-A.; Chen, Y.-I.; Wang, Y.; Korkmaz, Z.; Yonas, S.; He, Y.; Nguyen, T. D.; Hong, S.; Nguyen, A.-T.; Kim, S.; Seifi, S.; Fan, P.-H.; Wu, Y.; Yang, Z.; Liu, H.-W.; Lu, Y.; Ren, P.; Yeh, H.-C.

10.1101/2024.07.07.602435 — biophysics — Posted on 2024-07-10

3554 A differentiable Gillespie algorithm for simulating chemical kinetics, parameter estimation, and designing synthetic biological circuits

Rijal, K.; Mehta, P.

10.1101/2024.07.07.602397 — biophysics — Posted on 2024-07-10

3555 Predicting Enzyme Functions Using Contrastive Learning with Hierarchical Enzyme Structure Information

Duan, H.; Li, Z.; Wu, Y.; Chen, W.; Xia, L. C.

10.1101/2024.07.07.602424 — bioinformatics — Posted on 2024-07-10

3556 Mutational Constraint Analysis Workflow for Overlapping Short Open Reading Frames and Genomic Neighbours

Danner, M.; Begemann, M.; Kraft, F.; Elbracht, M.; Kurth, I.; Krause, J.

10.1101/2024.07.07.602395 — bioinformatics — Posted on 2024-07-10

3557 Extracellular vesicle-derived miRNA-mediated cell-cell communication inference for single-cell transcriptomic data with miRTalk

Shao, X.; Li, C.; Qian, J.; Yang, H.; Yang, X.; Liao, J.; Xu, X.; Fan, X.

10.1101/2024.07.07.602386 — bioinformatics — Posted on 2024-07-10

3558 Fully synthetic hydrogels promote robust crypt formation in intestinal organoids

Hushka, E. A.; Blatchley, M. R.; Macdougall, L. J.; Yavitt, F. M.; Kirkpatrick, B. E.; Bera, K.; Dempsey, P. J.; Anseth, K. S.

10.1101/2024.07.06.602364 — bioengineering — Posted on 2024-07-10

3559 Synchronous assembly of peptide anisosome

Zhou, L.; Zhu, L.; Wang, C.; Xu, T.; Wang, J.; Zhang, B.; Zhang, X.; Wang, H.

10.1101/2024.07.07.602414 — bioengineering — Posted on 2024-07-10

3560 3D bioprinting of low-viscosity phase-separated food-grade bioinks by in situ self-assembly

DeSantis, G.; Pastrana, L. M.; Oliveira, S. M.

10.1101/2024.07.06.602353 — bioengineering — Posted on 2024-07-10

3561 Quantifying social roles in multi-animal videos using subject-aware deep-learning

Goss, K.; Bueno-Junior, L. S.; Stangis, K.; Ardoin, T.; Carmon, H.; Zhou, J.; Satapathy, R.; Baker, I.; Jones-Tinsley, C. E.; Lim, M. M.; Watson, B. O.; Sueur, C.; Ferrario, C. R.; Murphy, G. G.; Ye, B.; Hu, Y.

10.1101/2024.07.07.602350 — animal behavior and cognition — Posted on 2024-07-10

3562 Shared foraging grounds in a solitary rodent: indication for cooperation by kin selection and mutualism?

Makuya, L.; Pillay, N.; Schradin, C.

10.1101/2024.07.07.602396 — animal behavior and cognition — Posted on 2024-07-10

3563 Pre-implantation genome-wide methylation enables environmental adaptation in a social meso-carnivore

Hung, T. H.; Tsai, M.-s.; Newman, C.; Buesching, C. D.; Macdonald, D. W.

10.1101/2024.07.07.602321 — genomics — Posted on 2024-07-10

3564 SMCHD1 maintains heterochromatin and genome compartments in human myoblasts

Huang, Z.; Cui, W.; Ratnayake, I.; Tawil, R.; Pfeifer, G. P.

10.1101/2024.07.07.602392 — genomics — Posted on 2024-07-10

3565 Identification of the sequences responsible for maternal H19-ICR hypermethylation with Beckwith-Wiedemann syndrome-like overgrowth in mice

Hara, S.; Matsuhisa, F.; Kitajima, S.; Yatsuki, H.; Kubiura-Ichimaru, M.; Soejima, H.

10.1101/2024.07.07.602442 — genetics — Posted on 2024-07-10

3566 A computer vision-based approach for estimating carbon fluxes from sinking particles in the ocean

Amaral, V. J.; Durkin, C. A.

10.1101/2024.07.06.602339 — ecology — Posted on 2024-07-10

3567 Lung Microbiome Intervention Attenuates Herpesvirus-Induced Post-HCT Pulmonary Fibrosis Through PD-L1 Upregulation on Dendritic Cells

Perkins, J. B.; Ravi, K.; Guo, C.; Oh, G. J.; Rodriguez, B. G.; Gurczynski, S. J.; Weinberg, J. B.; Huffnagle, G. B.; O'Dwyer, D. N.; Moore, B. B.; Zhou, X.

10.1101/2024.07.06.602351 — immunology — Posted on 2024-07-10

3568 Nasal tissue-resident memory CD4+ T cells persist after influenza A virus infection and provide heterosubtypic protection

Mathew, N. R.; Gailleton, R.; Scharf, L.; Schön, K.; Strömberg, A.; Lycke, N.; Bemark, M.; Tang, K.-W.; Angeletti, D.

10.1101/2024.07.06.602325 — immunology — Posted on 2024-07-10

3569 Xenon and nitrous oxide induced changes in resting EEG activity can be explained by systematic increases in the relaxation rates of stochastically driven alpha band oscillatory activity

Evertz, R.; Pelentritou, A.; Cormack, J.; Hicks, D. G.; Liley, D. T. J.

10.1101/2024.07.07.602148 — neuroscience — Posted on 2024-07-10

3570 Dihydromyricetin alleviated the damage of hypoxia-induced mouse neurons by reducing ROS levels and inhibiting the expression of PAR and gammaH2AX

Du, X.; Guo, Y.; Yang, J.

10.1101/2024.07.07.602423 — neuroscience — Posted on 2024-07-10

3571 Sexually dimorphic auditory representation in Aedes aegypti brains

Ohashi, T. S.; Xu, Y. Y. J.; Shigaki, S.; Nakamura, Y.; Lee, T.-T.; Loh, Y. M.; Mishiro-Sato, E.; Eberl, D. F.; Su, M. P.; Kamikouchi, A.

10.1101/2024.07.07.602439 — neuroscience — Posted on 2024-07-10

3572 Hair Cells Loss Estimation from Audiograms

Furst, M.; Koral, Y.; Zorea, A.

10.1101/2024.07.07.602394 — neuroscience — Posted on 2024-07-10

3573 Decoding the Epigenetic Landscape: Insights into 5mC and 5hmC Patterns in Mouse Cortical Cell Types

Wei, X.; Li, J.; Cheng, Z.; Wei, S.; Yu, G.; Olsen, M. L.

10.1101/2024.07.06.602342 — neuroscience — Posted on 2024-07-10

3574 Mouse parasubthalamic Crh neurons drive alcohol drinking escalation and behavioral disinhibition

Kreifeldt, M.; Okhuarobo, A.; Dunning, J. L.; Lopez, C.; Macedo, G.; Sidhu, H.; Contet, C.

10.1101/2024.07.06.602357 — neuroscience — Posted on 2024-07-10

3575 Single-Platelet Mapping of Jugular, Puncture-Wound Thrombi Reveals the Spatial Evolution of Platelet Activation

Rhee, S.; Pokrovskaya, I. D.; Ball, K. K.; Webb, M. W.; Kamykowski, J. A.; Zhao, O.; Driehaus, E. R.; Aronova, M. A.; Whiteheart, S. W.; Leapman, R. D.; Storrie, B.

10.1101/2024.07.07.602390 — systems biology — Posted on 2024-07-10

3576 Ventricular lymphatic vessel density correlates with mild cardiac remodelling and preserved heart function in moderate murine aortic valve stenosis

Becker, K.

10.1101/2024.07.06.602334 — physiology — Posted on 2024-07-10

3577 Computational simulations of Pachycrocuta bite damage based on a ~1.2 Ma ravaged hippopotamus femur from Fuente Nueva 3 (Orce, Granada, Spain)

Courtenay, L. A.; Serrano-Ramos, A.; Barsky, D.; Jimenez-Arenas, J.-M.; Yravedra, J.

10.1101/2024.07.07.602373 — paleontology — Posted on 2024-07-10

3578 Body oscillations reduce the aerodynamic power requirement of wild silkmoth flight

Sikandar, U. B.; Aiello, B. R.; Sponberg, S.

10.1101/2024.07.07.602433 — biophysics — Posted on 2024-07-10

3579 Biomolecular condensates can function as inherent catalysts

Guo, X.; Farag, M.; Qian, N.; Yu, X.; Ni, A.; Ma, Y.; Yu, W.; King, M.; Liu, V.; Lee, J.; Min, W.; Zare, R. N.; Pappu, R. V.; Dai, Y.

10.1101/2024.07.06.602359 — biophysics — Posted on 2024-07-10

3580 Accelerated Missense Mutation Identification in Intrinsically Disordered Proteins using Deep Learning

Bhattacharya, A.; Seth, S.

10.1101/2024.07.07.602404 — bioinformatics — Posted on 2024-07-10

3581 Integrated functional genomic analysis identifies the regulatory variants underlying a major QTL for disease resistance in European sea bass

Mukiibi, R.; Ferraresso, S.; Franch, R.; Peruzza, L.; Rovere, G. D.; Babbucci, M.; Bertotto, D.; Toffan, A.; Pascoli, F.; Faggion, S.; Penaloza, C.; Tsigenopoulos, C. S.; Houston, R. D.; Bargelloni, L.; Robledo, D.

10.1101/2024.07.06.602346 — genetics — Posted on 2024-07-10

3582 Genomics of Neotropical biodiversity indicators: two butterfly radiations with rampant chromosomal rearrangements and hybridisation

van der Heijden, E. S.; Nasvall, K.; Beserra Nobre, C. E.; Seixas, F. A.; Campos D Maia, A.; Salazar-Carrion, P. A.; Walker, J. M.; Szczerbowski, D.; Schulz, S.; Warren, I. A.; Gavilanes Cordova, K. G.; Sanchez-Carvajal, M. J.; Chandi, F.; Arias-Cruz, A. P.; Rueda-Munoz, N.; Salazar, C.; Dasmahapatra, K. K.; Montgomery, S. H.; McClure, M.; Absolon, D. E.; Mathers, T. C.; Santos, C. A.; McCarthy, S.; Wood, J.; Bacquet, C.; Freitas, A. V.; Willmott, K. R.; Jiggins, C. D.; Elias, M.; Meier, J. I.

10.1101/2024.07.07.602206 — evolutionary biology — Posted on 2024-07-10

3583 Global-scale quantification of responses to anthropogenic stressors in six riverine organism groups

Kaijser, W.; Schuerings, C.; Schneider, A.; Prati, S.; Musiol, M.; Wenskus, F.; Brauer, V. S.; Feldhaus, L.; Wagner, C. S.; Bayer, R.; Madge Pimentel, I.; Birk, S.; Mario, B.; Dunne, L.; Enss, J.; Farias, L.; Feld, C. K.; Gillmann, S. M.; Hupalo, K.; Osakpolor, S. E.; Olberg, S.; Schlautmann, C.; Schwelm, J.; Wells, N. E.; Sures, B.; Schaefer, R. B.; Hering, D.

10.1101/2024.07.06.602319 — ecology — Posted on 2024-07-10

3584 Orchid mycorrhizal communities associated with Orchis italica are shaped by ecological factors and geographical gradients

Balducci, M. G.; Calevo, J.; Duffy, K. J.

10.1101/2024.07.06.601878 — ecology — Posted on 2024-07-10

3585 Basement membrane patterning by spatial deployment of a secretion-regulating protease

Ku, H.-Y.; Bilder, D.

10.1101/2024.07.06.602330 — developmental biology — Posted on 2024-07-10

3586 Modulation of microglia activation after human donor retinal ganglion cell transplantation

Malechka, V.; Phay, M. H.; Augustine, J.; Rivera, J. D.; Alt, C.; Gregory-Ksander, M.; Baranov, P.

10.1101/2024.07.06.602307 — cell biology — Posted on 2024-07-10

3587 Temporal-spatially metabolic reprogramming rewires the H3K27ac landscape to enable the initiation of liver regeneration

Zheng, Q.; Li, X.; Xu, Z.; Cai, Y.; Li, F.; Xue, X.; Li, S.; Fan, G.; Sun, R.; Wu, J.; Qu, J.; Liu, R.

10.1101/2024.07.07.602368 — cell biology — Posted on 2024-07-10

3588 Impact of Equilibrative Nucleoside Transporters TgAT1, TgENT1, and TgENT3 on Toxoplasma gondii Infection and Differentiation

Goerner, A.; Messina, G.; Drogalis Beckham, L.; Martorelli Di Genova, B.

10.1101/2024.07.10.601519 — microbiology — Posted on 2024-07-10

3589 Experience-dependent sex differences in the role of dorsal striatal dopamine D1 receptor activity in methamphetamine self-administration revealed by a novel TREND model.

Madhuranthakam, I.; Job, M. O.

10.1101/2024.07.06.601793 — neuroscience — Posted on 2024-07-10

3590 An avidity-driven mechanism of extracellular BMP regulation by Twisted gastrulation

Moore, G.; Forbes-Beadle, L.; Birchenough, H. L.; Baldock, C.; Ashe, H. L.

10.1101/2024.07.08.602551 — developmental biology — Posted on 2024-07-10

3591 De Novo Design of Integrin α5β1 Modulating Proteins for Regenerative Medicine

Wang, X.; Guillem-Marti, J.; Kumar, S.; Lee, D.; Cabrerizo-Aguado, D.; Werther, R.; Alamo, K. A. E.; Zhao, Y.-T.; Nguyen, A.; Kopyeva, I.; Huang, B.; Li, J.; Hao, Y.; Li, X.; Brizuela-Velasco, A.; Murray, A. N.; Gerben, S.; Roy, A.; DeForest, C. A.; Springer, T.; Ruohola-Baker, H.; Cooper, J.; Campbell, M. G.; Manero, J. M.; Ginebra, M.-P.; Baker, D.

10.1101/2024.06.21.600123 — bioengineering — Posted on 2024-07-10

3592 Novel Behavioral Assays Reveal Sex Specific Behavioral Syndromes in Anemonefish

Graham, G. J.; Wilton, I. M.; Panczyk, E. K.; Rhodes, J. S.

10.1101/2024.06.07.597983 — animal behavior and cognition — Posted on 2024-07-10

3593 Large-scale genome analyses provide insights into Hymenoptera evolution

He, C.; Yang, Y.; Zhao, X.; Li, J.; Cai, Y.; Peng, L.; Liu, Y.; Xiong, S.; Mei, Y.; Yan, Z.; Wang, J.; Xiao, S.; Teng, Z.; Gao, X.; Xue, H.; Fang, Q.; Ye, G.; Ye, X.

10.1101/2024.07.01.601370 — genomics — Posted on 2024-07-10

3594 Astrocyte-Derived Exosomes Regulate Sperm miR-34c Levels to Mediate the Transgenerational Effects of Paternal Chronic Social Instability Stress

Champroux, A.; Sadat-Shirazi, M.; Chen, X.; Yang, Y.; Feig, L.

10.1101/2024.06.17.599336 — genetics — Posted on 2024-07-10

3595 Early Embryonic Development of the German Cockroach Blattella germanica

Bar-Lev Viterbo, A.; Wexler, J. R.; Mayost- Lev-Ari, O.; Chipman, A. D.

10.1101/2024.07.08.602440 — developmental biology — Posted on 2024-07-10

3596 Emerging cooperativity between Oct4 and Sox2 governs the pluripotency network in mouse early embryos

Schöler, H. R.; Hou, Y.; Nie, Z.; Jiang, Q.; Velychko, S.; Heising, S.; Bedzhov, I.; Wu, G.; Adachi, K.

10.1101/2023.10.18.562912 — developmental biology — Posted on 2024-07-10

3597 Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury

Karam, J.; Ashfaq, N.; Benitez, C.; Morales, V.; Partida, E.; Hernandez, M.; Yokoyama, J.; Villegas, A.; Brown, B.; Sakthivel, P.; Anderson, A. J.; Cummings, B. J.

10.1101/2024.02.26.582018 — neuroscience — Posted on 2024-07-10

3598 Omissions of Threat Trigger Subjective Relief and Prediction Error-Like Signaling in the Human Reward and Salience Systems

Willems, A. L.; Van Oudenhove, L.; Vervliet, B.

10.1101/2023.08.15.553434 — neuroscience — Posted on 2024-07-10

3599 Brief targeting of resurgent STAT3 activation in chronic epilepsy for potent and enduring disease modification.

Hoffman, O. R.; Patterson, A.; Gohar, E.; Coleman, E.; Espina, J. E. C.; Schoenike, B.; Espinosa-Garcia, C.; Paredes, F.; Dingledine, R.; Maguire, J.; Roopra, A.

10.1101/2023.08.07.552299 — neuroscience — Posted on 2024-07-10

3600 Reproductive life history of an acoel worm

Chandra, V.; Tseng, S. E.; Kann, A. P.; Bolanos, D. M.; Srivastava, M.

10.1101/2024.07.09.602770 — zoology — Posted on 2024-07-10

3601 Global genomics of the man-o'-war (Physalia) reveal biodiversity at the ocean surface

10.1101/2024.07.10.602499 — zoology — Posted on 2024-07-10

3602 Peroxidasin is associated with a mesenchymal-like transcriptional phenotype and promotes invasion in metastatic melanoma

Smith-Diaz, C. C.; Kumar, A.; Das, A.; Pace, P.; Chitcholtan, K.; Magon, N. J.; Hossain, S. H. M.; Eccles, M. R.; Winterbourn, C. C.; Paumann-Page, M.

10.1101/2024.04.05.588346 — cancer biology — Posted on 2024-07-10

3603 miR-184 controls Dilp8 to regulate the timing of a critical developmental transition in Drosophila melanogaster

Fernandes, J.; Naseem, M.; MP, A. M.; Varghese, J.

10.1101/2024.07.08.602443 — developmental biology — Posted on 2024-07-10

3604 Cnidaria XIAP activates caspase-mediated cell death

Chen, Y.; Wu, M.; Yuan, Z.; Wang, Q.; Xu, H.; Sun, L.

10.1101/2024.07.06.602363 — cell biology — Posted on 2024-07-10

3605 Modulation of ribosomal subunit associations by eIF6 is critical for mitotic exit and cancer progression.

Roshan, P.; Biswas, A.; Anagnos, S.; Luebbers, R.; Harish, K.; Ahmed, S.; Li, M.; Nguyen, N.; Zhou, G.; Tedeschi, F.; Hathuc, V.; Lin, Z.; Hamilton, Z.; Origanti, S. S.

10.1101/2024.06.24.600220 — molecular biology — Posted on 2024-07-10

3606 Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5

Sumner, C. A.; Schwedler, J. L.; McCoy, K. M.; Holland, J. E.; Duva, V.; Gelperin, D.; Busygina, V.; Stefan, M. A.; Martinez, D. V.; Jurros, M. A.; Phillips, A. A.; Weilhammer, D. R.; Grigoryan, G.; Kent, M. S.; Harmon, B. N.

10.1101/2024.07.08.602599 — microbiology — Posted on 2024-07-10

3607 Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes

Franco-Enzastiga, U.; Inturi, N. N.; Natarajan, K.; Mwirigi, J. M.; Mazhar, K.; Schlachetzki, J. C.; Schumacher, M.; Price, T. J.

10.1101/2024.03.27.587047 — neuroscience — Posted on 2024-07-10

3608 Proteome-scale tissue mapping using mass spectrometry based on label-free and multiplexed workflows

Kwon, Y.; Woo, J.; Yu, F.; Williams, S. M.; Markillie, L. M.; Moore, R. J.; Nakaysu, E. S.; Chen, J.; Campbell-Thompson, M.; Mathews, C. E.; Nesvizhskii, A. I.; Qian, W.-J.; Zhu, Y.

10.1101/2024.03.04.583367 — systems biology — Posted on 2024-07-10

3609 Early-life glucocorticoids accelerate lymphocyte count senescence in roe deer

Lalande, L. D.; Bourgoin, G.; Carbillet, J.; Cheynel, L.; Debias, F.; Ferte, H.; Gaillard, J.-M.; Garcia, R.; Lemaitre, J.-F.; Palme, R.; Pellerin, M.; Peroz, C.; Rey, B. D.; Vuarin, P.; Gilot-Fromont, E.

10.1101/2024.05.24.595732 — physiology — Posted on 2024-07-10

3610 Single-molecule detection and super-resolution imaging with a portable and adaptable 3D-printed microscopy platform (Brick-MIC)

Moya Munoz, G. G.; Brix, O.; Klocke, P.; Harris, P. D.; Luna Piedra, J. R.; Wendler, N. D.; Lerner, E.; Zijlstra, N.; Cordes, T.

10.1101/2023.12.29.573596 — biophysics — Posted on 2024-07-10

3611 Leveraging a large language model to predict protein phase transition: a physical, multiscale and interpretable approach

Frank, M.; Ni, P.; Jensen, M.; Gerstein, M. B.

10.1101/2023.11.21.568125 — biophysics — Posted on 2024-07-10

3612 Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing

Nguyen, L. T.; Rakestraw, N. R.; Pizzano, B. L. M.; Young, C. B.; Huang, Y.; Beerensson, K. T.; Fang, A.; Antal, S. G.; Anamiss, K. V.; Peggs, C. M. D.; Yan, J.; Jing, Y.; Burdine, R. D.; Adamson, B.; Toettcher, J. E.; Myhrvold, C.; Jain, P. K.

10.1101/2024.07.09.602710 — bioengineering — Posted on 2024-07-10

3613 A model of task-level human stepping regulation yields semistable walking

Patil, N. S.; Dingwell, J. B.; Cusumano, J. P.

10.1101/2024.03.05.583616 — bioengineering — Posted on 2024-07-10

3614 Activation of Polycystin-1 Signaling by Binding of Stalk-derived Peptide Agonists

Pawnikar, S.; Magenheimer, B. S.; Joshi, K.; Nevarez-Munoz, E.; Haldane, A.; Maser, R. L.; Miao, Y.

10.1101/2024.01.06.574465 — biochemistry — Posted on 2024-07-10

3615 SIRT2-Mediated ACSS2 K271 Deacetylation Suppresses Lipogenesis Under Nutrient Stress

Karim, R.; Teng, W.; Behram, C. D.; Lin, H.

10.1101/2024.02.27.582293 — biochemistry — Posted on 2024-07-10

3616 Regulatory genome annotation of 33 insect species

Asma, H.; Tieke, E.; Deem, K. D.; Rahmat, J.; Dong, T.; Huang, X.; Tomoyasu, Y.; Halfon, M. S.

10.1101/2024.01.23.576926 — genomics — Posted on 2024-07-10

3617 A Developmental Mechanism to Regulate Alterna6ve Polyadenyla6on in an Adult Stem Cell Lineage

Gallicchio, L.; Reis Matias, N.; Morales-Polanco, F.; Nava, I.; Stern, S.; Zeng, Y.; Fuller, M. T.

10.1101/2024.03.18.585561 — developmental biology — Posted on 2024-07-10

3618 Acute BRCAness Induction and AR Signaling Blockage through CDK12/7/9 Degradation Enhances PARP Inhibitor Sensitivity in Prostate Cancer

Gui, F.; Jiang, B.; Jiang, J.; He, Z.; Tsujino, T.; Takai, T.; Arai, S.; Pana, C.; Koellermann, J.; Bradshaw, G. A.; Eisert, R.; Kalocsay, M.; Fassl, A.; Balk, S. P.; Kibel, A. S.; Jia, L.

10.1101/2024.07.09.602803 — cancer biology — Posted on 2024-07-10

3619 Reproducibly oriented cell divisions pattern the first flat body structures to set up dorsoventrality and de novo meristem formation in Marchantia polymorpha

Wallner, E.-S.; Dolan, L.

10.1101/2024.07.08.602509 — plant biology — Posted on 2024-07-10

3620 The West African lungfish secretes a living cocoon during aestivation with uncertain antimicrobial function

Palominos, M. F.; Bharadwaj, R.; Tralka, C.; Trang, K.; Aka, D.; Alami, M.; Andrews, D.; Bartlett, B.; Golde, C.; Liu, J.; Le-Pedroza, M.; Perrot, R.; Seiter, B.; Sparrow, C.; Shapira, M.; Martin, C. H.

10.1101/2024.07.05.602297 — physiology — Posted on 2024-07-10

3621 Single-cell analysis of pediatric acute myeloid leukemia samples uncovers treatment-resistant stem and mast cells

Ohlstrom, D.; Bakhtia, M.; Mumme, H.; Michaud, M.; Chien, F.; Pilcher, W.; Satpathy, S.; Bhasin, S.; Bhasin, M.

10.1101/2024.07.09.602801 — cancer biology — Posted on 2024-07-10

3622 Inferring cancer type-specific patterns of metastatic spread

Koyyalagunta, D.; Morris, Q.

10.1101/2024.07.09.602790 — cancer biology — Posted on 2024-07-10

3623 Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

Meany, E. L.; Klich, J. H.; Jons, C. K.; Mao, T.; Chaudhary, N.; Utz, A.; Baillet, J.; Song, Y. E.; Saouaf, O. M.; Ou, B. S.; Williams, S. C.; Eckman, N.; Irvine, D. J.; Appel, E.

10.1101/2024.07.05.602305 — bioengineering — Posted on 2024-07-10

3624 Extracellular ISG15 triggers ISGylation via a type-I interferon independent mechanism to regulate host response during virus infection

Miller, L. G.; Chiok, K.; Mariasoosai, C.; Mohanty, I.; Pandit, S.; Mehari, L.; Haas, A. L.; Natesan, S.; Miura, T. A.; Bose, S.

10.1101/2024.07.05.602290 — immunology — Posted on 2024-07-10

3625 Esophageal epithelial Ikkβ deletion promotes eosinophilic esophagitis in experimental allergy mouse model

Clevenger, M. H.; Wei, C.; Karami, A. L.; Tsikretsis, L.; Carlson, D. A.; Pandolfino, J. E.; Gonsalves, N.; Winter, D. R.; Whelan, K. A.; Tetreault, M.-P.

10.1101/2024.07.05.602313 — immunology — Posted on 2024-07-10

3626 Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry

Ma, X.; Zhang, J.; Jiang, Q.; Li, Y.; Yang, G.

10.1101/2024.07.05.602171 — immunology — Posted on 2024-07-10

3627 A Novel Ex Vivo Approach for Investigating Profibrotic Macrophage Polarization Using Murine Precision-Cut Lung Slices

Vierhout, M.; Ayoub, A.; Ali, P.; Kumaran, V.; Naiel, S.; Isshiki, T.; Koenig, J. F.; Kolb, M. R.; Ask, K.

10.1101/2024.07.05.602278 — immunology — Posted on 2024-07-10

3628 Main Sequence of Human Luminance-Evoked Pupil Dynamics

Coutinho, J. D.; Huang, J.; Lefevre, P.; Blohm, G.; Munoz, D. P.

10.1101/2024.07.05.602284 — neuroscience — Posted on 2024-07-10

3629 Chemogenetic control of GABAergic activity within the interpeduncular nucleus reveals dissociable behavioral components of the nicotine withdrawal phenotype

Miguelez Fernandez, A. M. M.; Netherton, S.; Niladhuri, S. B.; Rivera, P.; Tseng, K. Y.; Peters, C. J.

10.1101/2024.07.05.602259 — neuroscience — Posted on 2024-07-10

3630 Optimization and model averaging of histogram-based place cell firing rate maps using the point process framework

Okatan, M.

10.1101/2024.07.05.602233 — neuroscience — Posted on 2024-07-10

3631 Differential Anti-Inflammatory Effects of Electrostimulation in a Standardized Setting

Di Pietro, B.; Villata, S.; Dal MOnego, S.; Degasperi, M.; Ghini, V.; Guarnieri, T.; Plaksienko, A.; Liu, Y.; Pecchioli, V.; Manni, L.; Tenori, L.; Licastro, D.; Angelini, C.; Napione, L.; Frascella, F.; Nardini, C.

10.1101/2024.07.05.602081 — systems biology — Posted on 2024-07-10

3632 Multivalent binding model quantifies antibody species from systems serology

Abraham, A. A.; Tan, Z. C.; Shrestha, P.; Bozich, E. R.; Meyer, A. S.

10.1101/2024.07.05.602296 — systems biology — Posted on 2024-07-10

3633 Rapid evolution of gene expression patterns in flowering plants

Schuster, C.; Gabel, A.; Drost, H.-G.; Grosse, I.; Leyser, O.; Meyerowitz, E. M.

10.1101/2024.07.08.602577 — plant biology — Posted on 2024-07-10

3634 A negative correlation between the rate coefficient of repair after photoinhibition of cold acclimated plants and the mean annual temperature of the habitats of Arabidopsis thaliana ecotypes

Oguchi, R.; Nagano, S.; Pfleger, A.; Ozaki, H.; Hikosaka, K.; Osmond, B. C.; Chow, W. S.

10.1101/2024.07.07.602425 — plant biology — Posted on 2024-07-10

3635 Divide and conquer: Using RhizoVision Explorer to aggregate data from multiple root scans using image concatenation and statistical methods

Seethepalli, A.; Ottley, C.; Fine, A.; Cope, K.; Lagergren, J.; Iversen, C.; Kalluri, U.; York, L. M.

10.1101/2024.07.05.602287 — plant biology — Posted on 2024-07-10

3636 Nemacounter: A user-friendly software to accurately phenotype SCN cysts

Mejias, J.; Kozlowski, D. K. L.; Goshon, J.; Maier, T. R.; Baum, T. J.

10.1101/2024.07.07.602381 — plant biology — Posted on 2024-07-10

3637 The single-berry metabolomic clock paradigm reveals new stages and metabolic switches during grapevine berry development

Tavernier, F.; Savoi, S.; Torregrosa, L.; Hugueney, P.; Baltenweck, R.; Segura, V.; Romieu, C.

10.1101/2024.07.06.602344 — plant biology — Posted on 2024-07-10

3638 From forests to farming: identification of photosynthetic limitations in breadfruit across diverse environments

Dow, G. J.; Lincoln, N. K.; Autufuga, D.; Paull, R.

10.1101/2024.07.08.602079 — plant biology — Posted on 2024-07-10

3639 Natural variation in the Arabidopsis thaliana root and shoot response to boron deficiency reveals sensitive and responsive phenes and phylogenetic and geographic clustering of boron efficiency adaptations

Alcock, T. D.; Bienert, M. D.; Junker, A.; Tschiersch, H.; Meyer, R. C.; Kudamala, S.; von Wiren, N.; Altmann, T.; Bienert, G. P.

10.1101/2024.07.08.602492 — plant biology — Posted on 2024-07-10

3640 Exploring the Impact of Various Treatments on Gene Expression in Olive (Olea europaea L.) Drupes Affected by Phytophthora oleae: Insights from RNA sequencing-based transcriptome analysis.

Conti Taguali, S.; Riolo, M.; La Spada, F.; Cacciola, S. O.; Dionisio, G.

10.1101/2024.07.08.602446 — plant biology — Posted on 2024-07-10

3641 The relationship between distortion product otoacoustic emissions and audiometric thresholds in the extended high-frequency range

Hauser, S. N.; Hustedt-Mai, A. R.; Wichlinski, A.; Bharadwaj, H. M.

10.1101/2024.07.05.601801 — physiology — Posted on 2024-07-10

3642 Origin of division of labor is decoupled from polymorphism in colonial animals

Leventhal, S.; Edie, S. M.; Simpson, C.; Morrison, R.

10.1101/2024.07.05.602267 — paleontology — Posted on 2024-07-10

3643 Evolutionary dynamics in the decades preceding acute myeloid leukaemia

Watson, C.; Poon, Y. P. G. G.; MacGregor, H. A. J.; Fonseca, A. V. A.; Apostolidou, S.; Gentry-Maharaj, A.; Menon, U.; Blundell, J. R.

10.1101/2024.07.05.602251 — cancer biology — Posted on 2024-07-10

3644 Wide-field bond-selective fluorescence imaging: from single-molecule to cellular imaging beyond video-rate

Lee, D.; Wang, H.; Kocheril, P. A.; Bi, X.; Naji, N.; Wei, L.

10.1101/2024.07.05.601986 — biophysics — Posted on 2024-07-10

3645 Charge distribution and helical content tune the binding of septins amphipathic helix domain to lipid membranes

Edelmaier, C. J.; Klawa, S. J.; Mofidi, S. M.; Wang, Q.; Bhonge, S.; Vogt, E. J. D.; Curtis, B. N.; Shi, W.; Hanson, S. M.; Klotsa, D.; Forest, M. G.; Gladfelter, A. S.; Freeman, R.; Nazockdast, E.

10.1101/2024.07.05.602292 — biophysics — Posted on 2024-07-10

3646 Tumor Subtype Classification Tool for HPV-associated Head and Neck Cancers

Li, S.; Grab, B. F.; Qin, T.; Soppe, S.; Lopez, E.; Patil, S.; D'Silva, N. J.; Rozek, L. S.; Sartor, M. A.

10.1101/2024.07.05.601906 — bioinformatics — Posted on 2024-07-10

3647 FlowPacker: Protein side-chain packing with torsional flow matching

Lee, J. S.; Kim, P. M.

10.1101/2024.07.05.602280 — bioinformatics — Posted on 2024-07-10

3648 Draft genome of Palmaria palmata and intraspecific genetic variations in the North-East Atlantic

Rosignoli, S.; Inaba, M.; Schmid, M.; McHale, M.; Fort, A.; Edwards, M. D.; Mols Mortensen, A.; Bartle, R.; Endal, A.; Baud, A.; Maggs, C.; Sulpice, R.

10.1101/2024.07.05.602248 — genomics — Posted on 2024-07-10

3649 Current genomic deep learning models display decreased performance in cell type specific accessible regions

Kathail, P.; Shuai, R. W.; Chung, R.; Ye, C. J.; Loeb, G.; Ioannidis, N. M.

10.1101/2024.07.05.602265 — genomics — Posted on 2024-07-10

3650 Pathogenicity is associated with population structure in a fungal pathogen of humans

Hatmaker, E. A.; Barber, A. E.; Drott, M. T.; Sauters, T. J. C.; Alastruey-Izquierdo, A.; Garcia-Hermoso, D.; Kurzai, O.; Rokas, A.

10.1101/2024.07.05.602241 — evolutionary biology — Posted on 2024-07-10

3651 THE MOLECULAR MECHANISMS OF DEFENSIVE-GRADE ORGANIC ACID BIOSYNTHESIS IN GROUND BEETLES

Rork, A. M.; Xu, S.; Attygalle, A.; Renner, T.

10.1101/2024.07.05.601757 — evolutionary biology — Posted on 2024-07-10

3652 Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing and FastSurfer on MRI Processing

Hubner, S.; Tambalo, S.; Hilbert, T.; Kober, T.; Jovicich, J.

10.1101/2024.07.05.602237 — neuroscience — Posted on 2024-07-10

3653 Nonergodicity and Simpson's paradox in neurocognitive dynamics of cognitive control

Mistry, P. K.; Branigan, N. K.; Gao, Z.; Cai, W.; Menon, V.

10.1101/2024.07.05.602273 — neuroscience — Posted on 2024-07-10

3654 Deep-diffeomorphic networks for conditional brain templates

Whitbread, L.; Lau, S.; Palmer, L. J.; Jenkinson, M.

10.1101/2024.07.05.602288 — neuroscience — Posted on 2024-07-10

3655 Censored Least Squares for Imputing Missing Values in PARAFAC Tensor Factorization

Hung, E. S.; Tan, Z. C.; Meyer, A. S.

10.1101/2024.07.05.602272 — systems biology — Posted on 2024-07-10

3656 A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins

Hoernstein, S. N. W.; Schlosser, A.; Fiedler, K.; van Gessel, N.; Igloi, G. L.; Lang, D.; Reski, R.

10.1101/2024.06.11.598444 — plant biology — Posted on 2024-07-10

3657 Resolving multi-image spatial lipidomic responses to inhaled toxicants by machine learning

Stevens, N. C.; Shen, T.; Martinez, J.; Evans, V. J.; Domanico, M. C.; Neumann, E. K.; Van Winkle, L. S.; Fiehn, O.

10.1101/2024.07.05.602264 — pharmacology and toxicology — Posted on 2024-07-10

3658 Fluid mechanics of luminal transport in actively contracting endoplasmic reticulum

Htet, P. H.; Avezov, E.; Lauga, E.

10.1101/2023.01.11.523552 — biophysics — Posted on 2024-07-10

3659 An antimicrobial drug recommender system using MALDI-TOF MS and dual-branch neural networks

De Waele, G.; Menschaert, G.; Waegeman, W.

10.1101/2023.09.28.559916 — bioinformatics — Posted on 2024-07-10

3660 Assessment of variant effect predictors unveils variants difficulty as a critical performance indicator

Radjasandirane, R.; Diharce, J.; Gelly, J.-C.; de Bervern, A. G.

10.1101/2024.07.08.602580 — bioinformatics — Posted on 2024-07-10

3661 Structural basis for CCR6 modulation by allosteric antagonists

Wasilko, D. J.; Gerstenberger, B. S.; Farley, K. A.; Li, W.; Alley, J.; Schnute, M. E.; Unwalla, R. J.; Victorino, J.; Crouse, K. K.; Ding, R.; Sahasrabudhe, P. V.; Vincent, F.; Frisbie, R. K.; Dermenci, A.; Flick, A.; Choi, C.; Chinigo, G.; Mousseau, J. J.; Trujillo, J. I.; Nuhant, P.; Mondal, P.; Lombardo, V.; Lamb, D.; Hogan, B. J.; Minhas, G. S.; Segala, E.; Oswald, C.; Windsor, I. W.; Han, S.; Rappas, M.; Cooke, R. M.; Calabrese, M. F.; Berstein, G.; Thorarensen, A.; Wu, H.

10.1101/2024.04.05.588354 — biochemistry — Posted on 2024-07-10

3662 Machine Learning Uncovers the Transcriptional Regulatory Network for the Production Host Streptomyces albidoflavus

Jönsson, M.; Sigrist, R.; Gren, T.; Semenov Petrov, M.; Marcussen, N.; Svetlova, A.; Charusanti, P.; Palsson, B. O.; Yang, L.; Özdemir, E.

10.1101/2024.01.09.574332 — genomics — Posted on 2024-07-10

3663 An integrative taxonomy approach reveals Saccharomyces chiloensis sp. nov. as a newly discovered species from Coastal Patagonia

Pena, T. A.; Villarreal, P.; Agier, N.; Chiara, M. D.; Barria, T.; Urbina, K.; Villarroel, C. A.; Santos, A. R. O.; Rosa, C. A.; Nespolo, R. F.; Liti, G.; Fischer, G.; Cubillos, F.

10.1101/2024.04.29.591617 — genetics — Posted on 2024-07-10

3664 Does bumblebee preference of continuous over interrupted strings in string-pulling tasks indicate means-end comprehension?

Wen, C.; Lu, Y.; Solvi, C.; Dong, S.; Cai, W.; Haijun, X.; Jun, W. X.; Kui, D. S.; Wen, J.; Peng, F.; Chittka, L.

10.1101/2024.04.02.587731 — ecology — Posted on 2024-07-10

3665 UPF1 is required for gene expression in mitochondria and paternal mtDNA clearance during spermatogenesis

Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.

10.1101/2024.05.10.591322 — cell biology — Posted on 2024-07-10

3666 Insights into the RNA virome of the corn leafhopper Dalbulus maidis, a major emergent threat of Maize in Latin America

Debat, H. J.; Farrher, E. S.; Bejerman, N.

10.1101/2024.07.05.602261 — microbiology — Posted on 2024-07-10

3667 Characterization of Dnajc12 knockout mice, a model of hypodopaminergia

Deng, I. B.; Follet, J.; Fox, J. D.; Farrer, M. J.

10.1101/2024.07.06.602343 — neuroscience — Posted on 2024-07-10

3668 Preclinical evaluation of the novel CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease

Zajicek, F.; Verhaeghe, J.; de Lombaerde, S.; Van Eetveldt, A.; Miranda, A.; Munoz-Sanjuan, I.; Dominguez, C.; Khetarpal, V.; Bard, J.; Liu, L.; Staelens, S.; Bertoglio, D.

10.1101/2024.05.16.594492 — neuroscience — Posted on 2024-07-10

3669 MuPET-Flow: Multiple Ploidy Estimation Tool from Flow cytometry data

Gomez-Munoz, C.; Fischer, G.

10.1101/2024.01.24.577056 — bioinformatics — Posted on 2024-07-10

3670 Alternative TSS use is widespread in Cryptococcus fungi in response to environmental cues and regulated genome-wide by the transcription factor Tur1

Dang, T. T. V.; Maufrais, C.; Colin, J.; Moyrand, F.; Mouyna, I.; Coppee, J.-Y.; Onyishi, C. U.; Lipecka, J.; Guerrera, I. C.; May, R. C.; Janbon, G.

10.1101/2023.07.18.549460 — molecular biology — Posted on 2024-07-10

3671 Multisensory integration operates on correlated input from unimodal transients channels

Parise, C. V.; Ernst, M. O.

10.1101/2023.07.07.548109 — neuroscience — Posted on 2024-07-10

3672 Ablation of three major phospho-sites in RyR2 preserves the global adrenergic response but creates an arrhythmogenic substrate

Zheng, J.; Dooge, H.; Valdivia, H. H.; Alvarado, F. J.

10.1101/2024.07.08.602617 — physiology — Posted on 2024-07-10

3673 BRAT1 - a new therapeutic target for glioblastoma

Haydo, A. S.; Schmidt, J. H.; Crider, A.; Kögler, T.; Ertl, J.; Hehlgans, S.; Hoffmann, M. E.; Rathore, R.; Güllülü, O.; Wang, Y.; Zhang, X.; Herold-Mende, C.; Pampaloni, F.; Tegeder, I.; Dikic, I.; Dai, M.; Rödel, F.; Kögel, D.; Linder, B.

10.1101/2024.07.08.602519 — cancer biology — Posted on 2024-07-10

3674 Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing

Nguyen, L. T.; Rakestraw, N. R.; Pizzano, B. L.; Young, C. B.; Huang, Y.; Beerensson, K. T.; Fang, A.; Antal, S. G.; Anamiss, K. V.; Peggs, C. M.; Yan, J.; Jing, Y.; Burdine, R. D.; Adamson, B.; Toettcher, J. E.; Myhrvold, C.; Jain, P. K.

10.1101/2024.07.09.602710 — bioengineering — Posted on 2024-07-10

3675 Differential Survival In Carrion Crows Through Eavesdropping on Human Speech: An Agent-Based Model

Schalz, S.

10.1101/2023.09.15.557945 — animal behavior and cognition — Posted on 2024-07-10

3676 Df-1 Cell Adaptation and Immune Responses of Lc-75 Vaccinal Strain of Infectious Bursal Disease Virus in Chicken

Abate, F. M.; Ali, D. A.; Getachew, B.; Mohammed, H.

10.1101/2024.07.09.602647 — microbiology — Posted on 2024-07-10

3677 Evolutionary paleoecology of European rhinocerotids across the Oligocene-Miocene transition

Hullot, M.; Martin, C.; Blondel, C.; Becker, D.; Roessner, G. E.

10.1101/2024.04.17.589495 — paleontology — Posted on 2024-07-10

3678 Oncogenic NOVA1 expression dysregulates alternative splicing in breast cancer

Moakley, D. F.; Zhang, C.

10.1101/2024.07.08.602566 — cancer biology — Posted on 2024-07-10

3679 RBM10 loss induces aberrant splicing of cytoskeletal and extracellular matrix mRNAs and promotes metastatic fitness.

Krishnamoorthy, G. P.; Glover, A. R.; Untch, B. R.; Sigcha-Coello, N. F.; Xu, B.; Vukel, D.; Liu, Y.; Tiedje, V.; Berman, K.; Tamarapu, P. P.; Acuna-Ruiz, A.; Saqcena, M.; de Stanchina, E.; Boucai, L.; Ghossein, R. A.; Knauf, J. A.; Abdel-Wahab, O.; Bradley, R.; Fagin, J. A.

10.1101/2024.07.09.602730 — cancer biology — Posted on 2024-07-10

3680 Spatial transcriptomics unveils landscape of resistance to concurrent chemo-radiotherapy in hypopharyngeal squamous cell carcinoma: the role of SPP1+ macrophages

Ohn, J.; Bae, S.; Choi, H.; Kim, I. G.; Na, K. J.; Chung, E.-J.

10.1101/2024.07.09.602476 — cancer biology — Posted on 2024-07-10

3681 Transcriptional Characterization of Resistance in Early Drug Response

Ruoff, C.; Mitchell, A.; Mondal, P.; Gopalan, V.; Gottesman, M.; Hannenhalli, S.

10.1101/2024.07.05.602281 — cancer biology — Posted on 2024-07-10

3682 Asbestos Mineral Fibre Exposure Significantly Affects Volatile Organic Compound Profiles of Mesothelial Cell Lines In Vitro

Bonsall, S.; Issitt, T.; Peake, N.; Herigstad, M.; Webber, J.; Haywood-Small, S.

10.1101/2024.07.08.602545 — cancer biology — Posted on 2024-07-10

3683 CDK4/6 inhibitors promote PARP1 degradation and act synergistically with PARP inhibitors in non-small cell lung cancer

Roggero, C. M.; Ghosh, A. B.; Devineni, A.; Ma, S.; Blatt, E.; Raj, G. V.; Yin, Y.

10.1101/2024.07.07.602389 — cancer biology — Posted on 2024-07-10

3684 CLEC18A interacts with sulfated GAGs and controls clear cell renal cell carcinoma progression

Jonsson, G.; Hofmann, M.; Mereiter, S.; Hartley-Tassell, L.; Sakic, I.; Oliveira, T.; Hoffmann, D.; Novatchkova, M.; Schleiffer, A.; Penninger, J. M.

10.1101/2024.07.08.602586 — cancer biology — Posted on 2024-07-10

3685 Targeting NOTCH2-JAG1 juxtacrine signaling reverses macrophage-mediated tumor resistance to taxol

Yu, F.; Zhou, Q.; Zhou, T.; Xie, Y.; Zhang, P.; He, W.; Yu, W.; Cheng, A.; Liu, H.; Wu, Q.; Ma, X.; Guo, J.; Zhou, Y.; Shi, J.; Yang, Z.

10.1101/2024.07.08.602467 — cancer biology — Posted on 2024-07-10

3686 Ovarian cancer cells exhibit diverse migration strategies on stiff collagenous substrata

S, M.; Bhat, R.

10.1101/2024.07.08.602474 — cancer biology — Posted on 2024-07-10

3687 Osmotic Stress Influences Microtubule Drug Response Via WNK1 Kinase Signaling

Monfort-Vengut, A.; Sanz-Gomez, N.; Ballesteros-Sanchez, S.; Ortigosa, B.; Cambon, A.; Ramos, M.; Montes-San Lorenzo, A.; Rosa-Rosa, J. M.; Martinez-Lopez, J.; Sanchez-Prieto, R.; Sotillo, R.; de Carcer, G.

10.1101/2024.07.08.602030 — cancer biology — Posted on 2024-07-10

3688 In-silico studies on structural and thermodynamics basis of interaction of lac repressor protein binding to different DNA operators

Das, S.

10.1101/2024.07.07.602393 — biophysics — Posted on 2024-07-10

3689 Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding

Huynh, D.; Hoffmeister, P.; Friedrich, T.; Zhang, K.; Bartkuhn, M.; Ferrante, F.; Giaimo, B. D.; Kovall, R.; Borggrefe, T.; Oswald, F.; Gebhardt, J. C. M.

10.1101/2023.12.19.572376 — biophysics — Posted on 2024-07-10

3690 Memory-bound k-mer selection for large evolutionary diverse reference libraries

Sapci, A. O. B.; Mirarab, S.

10.1101/2024.02.12.580015 — bioinformatics — Posted on 2024-07-10

3691 microGWAS: a computational pipeline to perform large scale bacterial genome-wide association studies

Burgaya, J.; Damaris, B. F.; Fiebig, J.; Galardini, M.

10.1101/2024.07.08.602456 — bioinformatics — Posted on 2024-07-10

3692 Hybrid protein-ligand binding residue prediction with protein language models: Does the structure matter?

Gamouh, H.; Hoksza, D.; Novotny, M.

10.1101/2023.08.11.553028 — bioinformatics — Posted on 2024-07-10

3693 Haplotype-aware multiomics unveils the regulatory basis of haplodiplontic life-cycle differentiation in a cosmopolitan marine alga

Kao, T.-T.; Lai, M.-W.; Wang, T.-H.; Yang, C.-L.; Frada, M.; Ku, C.

10.1101/2024.05.26.595999 — genomics — Posted on 2024-07-10

3694 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour

Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.

10.1101/2024.02.19.581047 — cell biology — Posted on 2024-07-10

3695 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.

10.1101/2024.02.20.581122 — microbiology — Posted on 2024-07-10

3696 Ly6G+Granulocytes-derived IL-17 limits protective host responses and promotes tuberculosis pathogenesis

Sharma, P.; Sharma, R. D.; Das, M.; Sarkar, B.; Singh, L.; Jain, N.; Chaturvedi, S.; Mehra, L.; Rathee, A.; Sharma, S.; Shihui, F.; Lee, A.; Kumar, P. N.; Das, P.; Viswanathan, V.; Kornfeld, H.; Howland, S.; Babu, S.; Nandicoori, V.; Singhal, A.; Kumar, D.

10.1101/2023.10.05.561061 — immunology — Posted on 2024-07-10

3697 Cost-benefit Tradeoff Mediates the Rule- to Memory-based Processing Transition during Practice

Yang, G.; Jiang, J.

10.1101/2024.02.13.580214 — neuroscience — Posted on 2024-07-10

3698 Identifying a Distractor Produces Object-Based Inhibition in an Allocentric Reference Frame for Saccade Planning

Olenick, C. E.; Jordan, H.; Fallah, M.

10.1101/2024.01.30.578028 — neuroscience — Posted on 2024-07-10

3699 Recent visual experience reshapes V4 neuronal activity and improves perceptual performance

Stan, P. L.; Smith, M. A.

10.1101/2023.08.27.555026 — neuroscience — Posted on 2024-07-10

3700 Generation of the First Transgenic Line of the Iconic Coral Reef Fish Amphiprion ocellaris

Graham, G. J.; Ibanez, E. M.; Mitchell, L. J.; Weis, K. E.; Raetzman, L. T.; Cortesi, F.; Rhodes, J. S.

10.1101/2024.06.05.597662 — bioengineering — Posted on 2024-07-10

3701 A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.

Tesson, F.; Planel, R.; Egorov, A. A.; Georjon, H.; Vaysset, H.; Brancotte, B.; Neron, B.; Mordret, E.; Atkinson, G. C.; Bernheim, A.; Cury, J.

10.1101/2024.01.25.577194 — genomics — Posted on 2024-07-10

3702 Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection

Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.

10.1101/2023.06.28.546652 — genomics — Posted on 2024-07-10

3703 Identifying conservation priorities of a pantropical plant lineage: a case study in Scleria (Cyperaceae)

Galan Diaz, J.; Bachman, S. P.; Forest, F.; Escudero, M.; Rotton, H.; Larridon, I.

10.1101/2024.06.21.600016 — ecology — Posted on 2024-07-10

3704 Cryptic genetic structure of the coral host is the primary driver of holobiont assembly in massive Porites

Scott, C. B.; Schott, R.; Matz, M. V.

10.1101/2024.01.09.574877 — ecology — Posted on 2024-07-10

3705 Membrane potential mediates an ancient mechano-transduction mechanism for multi-cellular homeostasis

Mukherjee, A.; Huang, Y.; Elgeti, J.; Oh, S.; Abreu, J.; Neliat, A. R.; Schuttler, J.; Su, D.; Dupre, C.; Benites, N. C.; Liu, X.; Peshkin, L.; Barboiu, M.; Stocker, H.; Kirschner, M. W.; Basan, M.

10.1101/2023.11.02.565386 — cell biology — Posted on 2024-07-10

3706 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum

Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.

10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-10

3707 Evolution of genotypic and phenotypic diversity in multispecies biofilms

Amador, C. I.; Moskovitz, S. Z.; Maccario, L.; Herschend, J.; Kramer, I. S.; Jeckel, H.; Cooper, V. S.; Drescher, K.; Neu, T. R.; Burmolle, M.; Roder, H. L.

10.1101/2023.10.08.561388 — microbiology — Posted on 2024-07-10

3708 Converging Topographic Axes of Connectivity and Genetic Architectures Scaffold Cortical Patterning

Li, D.; Wang, Y.; Ma, L.; Wang, Y.; Cheng, L.; Liu, Y.; Shi, W.; Lu, Y.; Wang, H.; Gao, C.; Erichsen, C.; Zhang, Y.; Yang, Z.; Eickhoff, S.; Chen, C.-h.; Jiang, T.; Chu, C.; Fan, L.

10.1101/2023.09.06.556618 — neuroscience — Posted on 2024-07-10

3709 N-Glycosylation of MRS2 balances aerobic and anaerobic energy production by reducing rapid mitochondrial Mg2+ influx in conditions of high glucose or impaired respiratory chain function

Peng, M.; Mathew, N. D.; Anderson, V. E.; Falk, M. J.; Nakamura-Ogiso, E.

10.1101/2024.07.09.602756 — biochemistry — Posted on 2024-07-10

3710 Relaxed selection can speed the evolution of complex adaptations

Draghi, J. A.; Ogbunugafor, C. B.; Zaman, L.; Parsons, T.

10.1101/2024.07.09.602773 — evolutionary biology — Posted on 2024-07-09

3711 Rapid loss of genetic variation and increased inbreeding in small and isolated populations of Norwegian wild reindeer

Hansen, B. B.; Peeters, B.; Flagstad, O.; Roed, K. H.; Martin, M. D.; Jensen, H.; Burnett, H. A.; Bieker, V. C.; Mysterud, A.; Sun, X.; Cote, S. D.; Robert, C.; Rolandsen, C. M.; Strand, O.

10.1101/2024.07.09.598942 — genetics — Posted on 2024-07-09

3712 Dynamic stress- and inflammatory-based regulation of psychiatric risk loci in human neurons

Retallick-Townsley, K. G.; Lee, S.; Cartwright, S.; Cohen, S.; Sen, A.; Jia, M.; Young, H.; Dobbyn, L.; Deans, M.; Fernandez-Garcia, M.; Huckins, L. M.; Brennand, K. J.

10.1101/2024.07.09.602755 — genetics — Posted on 2024-07-09

3713 Age-dependent predictors of effective reinforcement motor learning across childhood

Hill, N. M.; Tripp, H. M.; Wolpert, D. M.; Malone, L. A.; J Bastian, A.

10.1101/2024.07.09.602665 — neuroscience — Posted on 2024-07-09

3714 Sex-specific GABAergic microcircuits that switch vulnerability into resilience to stress and reverse the effects of chronic stress exposure

Jiang, T.; Feng, M.; Hutsell, A.; Luscher, B.

10.1101/2024.07.09.602716 — neuroscience — Posted on 2024-07-09

3715 A dendritic substrate for temporal diversity of cortical inhibition

Morabito, A.; Zerlaut, Y.; Dhanasobhon, D.; Berthaux, E.; Tzilivaki, A.; Moneron, G.; Cathala, L.; Poirazi, P.; Bacci, A.; DiGregorio, D.; Lourenco, J.; Rebola, N.

10.1101/2024.07.09.602783 — neuroscience — Posted on 2024-07-09

3716 Environmental controls on crenarchaeol distributions in hydrothermal springs

Calhoun, A. N.; Blewett, J.; Colman, D.; Amenabar, M. J.; Harris, C. M.; Boyd, E.; Pearson, A.; Leavitt, W. D.

10.1101/2024.07.09.602736 — microbiology — Posted on 2024-07-09

3717 Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites

Wang, B.; Peng, X.; Zhou, X.; Siddique, A.; Yao, J.; Zhang, H.; Li, W.; Li, Y.; Yue, M.

10.1101/2024.07.09.602698 — microbiology — Posted on 2024-07-09

3718 Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans

Kumar, A.; Saha, M. K.; Kumar, V.; Bhattacharya, A.; Barge, S.; Mukherjee, A. K.; Kalita, M. C.; Khan, M. R.

10.1101/2024.07.09.602715 — microbiology — Posted on 2024-07-09

3719 Metagenomic insights into the development of microbial communities of straw and leaf composts.

Kimeklis, A. K.; Gladkov, G. V.; Orlova, O. V.; Lisina, T. O.; Afonin, A. M.; Aksenova, T. S.; Kichko, A. A.; Lapidus, A.; Abakumov, E. V.; Andronov, E. E.

10.1101/2024.07.08.602579 — microbiology — Posted on 2024-07-09

3720 Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5

10.1101/2024.07.08.602599 — microbiology — Posted on 2024-07-09

3721 A magnesium transporter CorA of Mycobacterium smegmatis enhances the tolerance of structurally unrelated antibiotics in the host cells

Chatterjee, D.; Daya Manasi, A. R.; Rastogi, S. K.; Panda, A. P.; Biju, B.; Bhattacharyya, D.; Ghosh, A. S.

10.1101/2024.07.09.602764 — microbiology — Posted on 2024-07-09

3722 Transcription Factors DksA and PsrA are synergistic contributors to L. pneumophila virulence in Acathamoeba castellanii protozoa

Graham, C. I.; MacMartin, T. L.; Penner, T. V.; Beck, J. C.; Gierys, A. J.; Prehna, G.; de Kievit, T. R.; Brassinga, A. K. C.

10.1101/2024.07.09.602712 — microbiology — Posted on 2024-07-09

3723 Bacteriophage resistance evolution in a honey bee pathogen

Van Leuven, J.; Miller, C.; Peters, T.; Spencer, E.; Eline, Y.; Paull, K.; Saucedo, L.; Linzan, K.

10.1101/2024.07.09.602782 — microbiology — Posted on 2024-07-09

3724 Genome-resolved year-round dynamics reveal a broad range of giant virus microdiversity

Fang, Y.; Meng, L.; Xia, J.; Gotoh, Y.; Hayashi, T.; Nagasaki, K.; Endo, H.; Okazaki, Y.; Ogata, H.

10.1101/2024.07.08.602415 — microbiology — Posted on 2024-07-09

3725 Illuminating microbial phosphorus cycling in deep-sea cold seep sediments using protein language models

Zhang, C.; He, Y.; Wang, J.; Chen, T.; Baltar, F.; Hu, M.; Liao, J.; Xiao, X.; Li, Z.-R.; Dong, X.

10.1101/2024.07.09.602434 — microbiology — Posted on 2024-07-09

3726 A HigB-like toxin promotes non-replicating Salmonella inside macrophages by inhibiting ribonuclease III

Choi, S.; Cho, Y.-J.; Baek, S.; Choi, E.; Kim, Y. K.; Lee, E.-J.

10.1101/2024.07.09.602740 — microbiology — Posted on 2024-07-09

3727 TgATG9 is required for autophagosome biogenesis and maintenance of chronic infection in Toxoplasma gondii

Thaprawat, P.; Zhang, Z.; Rentchler, E. C.; Wang, F.; Chalasani, S.; Giuliano, C. J.; Lourido, S.; Di Cristina, M.; Klionsky, D. J.; Carruthers, V. B.

10.1101/2024.07.08.602581 — microbiology — Posted on 2024-07-09

3728 The Haemagglutinin Genes of the UK Clade 2.3.4.4b H5N1 Avian Influenza Viruses from 2020 to 2022 Retain Strong Avian Phenotype

Yang, J.; Daines, R.; Chang, P.; Karunarathna, T. K.; Qureshi, M.; Sadeyen, J.-R.; James, J.; Banyard, A. C.; Slomka, M. J.; Brown, I. H.; Iqbal, M.

10.1101/2024.07.09.602706 — microbiology — Posted on 2024-07-09

3729 Microbial Hauberks: Composition and Function of Surface Layer Proteins in Gammaproteobacterial Methanotrophs

Hamilton, R.; Gebbie, W.; Bowman, C.; Mantanona, A.; Kalyuzhnaya, M. G.

10.1101/2024.07.09.602694 — microbiology — Posted on 2024-07-09

3730 Structures of Epstein-Barr virus and Kaposi's sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

Zhen, J.; Chen, J.; Huang, H.; Liao, S.; Liu, S.; Yuan, Y.; Sun, R.; Wu, T.-T.; Longnecker, R.; Zhou, H.

10.1101/2024.07.09.602672 — microbiology — Posted on 2024-07-09

3731 Optogenetic control of a horizontally acquired region in yeast prevent stuck fermentations

Figueroa, D.; Ruiz, D.; Tellini, N.; De Chiara, M.; Kessi-Perez, E. I.; Martinez, C.; Liti, G.; Querol, A.; Guillamon, J. M.; Salinas, F.

10.1101/2024.07.09.602721 — microbiology — Posted on 2024-07-09

3732 Triton-X 100-treated virus-based ELLA demonstrates discordant antigenic evolution of influenza B virus haemagglutinin and neuraminidase

Koutsakos, M.; Do, T. T. H.; Wille, M.; Wheatley, A. K.

10.1101/2024.07.09.602673 — microbiology — Posted on 2024-07-09

3733 Chronic wounds and adaptive Pseudomonas aeruginosa: A phenotypic and genotypic characterization

Buchholtz, K.; Joensson, R.; Marvig, R. L.; Mojsoska, B.; Krogfelt, K. A.

10.1101/2024.07.08.602036 — microbiology — Posted on 2024-07-09

3734 Deletion of HindIIR and HindIIIR improves DNA transfer via electroporation to Haemophilus influenzae Rd

Hamadache, S.; Huang, Y. K.; Shedeed, A.; Syed, A.; Karas, B. J.

10.1101/2024.07.09.602704 — synthetic biology — Posted on 2024-07-09

3735 SARS-CoV-2 shedding dynamics in human respiratory tract

Jin, X.; Ren, L.; Ren, X.; Wang, J.

10.1101/2024.07.09.602697 — bioinformatics — Posted on 2024-07-09

3736 Metagenome-assembled genomes of Estonian Microbiome cohort reveal novel species and their links with prevalent diseases

Pantiukh, K.; Aasmets, O.; Krigul, K. L.; Org, E.

10.1101/2024.07.06.602324 — bioinformatics — Posted on 2024-07-09

3737 Zonal Patterning of Extracellular Matrix and Stromal Cell Populations Along a Perfusable Cellular Microchannel

Chernokal, B.; Ferrick, B. J.; Gleghorn, J. P.

10.1101/2024.07.09.602744 — bioengineering — Posted on 2024-07-09

3738 High Throughput Variant Libraries and Machine Learning Yield Design Rules for Retron Gene Editors

Crawford, K. D.; Khan, A. G.; Lopez, S. C.; Goodarzi, H.; Shipman, S.

10.1101/2024.07.08.602561 — bioengineering — Posted on 2024-07-09

3739 Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands

Kang, Y.; Lyu, Z.; Lyu, X.; Xia, G.; Carney, D.; Alves, V. M.; Falk, M.; Arora, N.; Zou, H.; McGrath, A.

10.1101/2024.07.08.602624 — biochemistry — Posted on 2024-07-09

3740 Short-Term Warming Induces Cyanobacterial Blooms and Antibiotic Resistance in a Freshwater Lake as Revealed by Metagenomics Analysis

Manna, B.; Jay, E.; Zhang, W.; Zhou, X.; Lyu, B.; Thomas, G. M.; Singhal, N.

10.1101/2024.07.08.602497 — genomics — Posted on 2024-07-09

3741 HyperCas12a enables highly-multiplexed epigenome editing screens

Melore, S. M.; Hamilton, M. C.; Reddy, T. E.

10.1101/2024.07.08.602263 — genomics — Posted on 2024-07-09

3742 Comprehensive deletion scan of anti-CRISPR AcrIIA4 reveals essential and dispensable domains for Cas9 inhibition

Iturralde, A. B.; Weller, C. A.; Sadhu, M. J.

10.1101/2024.07.09.602757 — genetics — Posted on 2024-07-09

3743 The RRM domain-containing protein Rbp3 interacts with ribosomes and the 3' ends of mRNAs encoding photosynthesis proteins

Hemm, L.; Lichtenberg, E.; Tholen, S.; Reimann, V.; Kakazu, K.; Machida, S.; Mahbub, M.; Schilling, O.; Wilde, A.; Watanabe, S.; Mullineaux, C. W.; Hess, W. R.

10.1101/2024.07.09.602696 — microbiology — Posted on 2024-07-09

3744 Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent Infection

Cuddy, S.; Krakowiak, P. A.; Flores, M. E.; Whitford, A. L.; Dochnal, S. A.; Babnis, A.; Miyake, T.; Tigano, M.; Engel, D. A.; Cliffe, A. R.

10.1101/2024.07.06.601241 — microbiology — Posted on 2024-07-09

3745 Stable recurrent dynamics in heterogeneous neuromorphic computing systems using excitatory and inhibitory plasticity

Maryada, ; Soldado-Magraner, S.; Sorbaro, M.; Laje, R.; Buonomano, D.; Indiveri, G.

10.1101/2023.08.14.553298 — neuroscience — Posted on 2024-07-09

3746 The recombination landscape of introgression in yeast

Schwarzkopf, E. J.; Brandt, N.; Smukowski Heil, C.

10.1101/2024.01.04.574263 — evolutionary biology — Posted on 2024-07-09

3747 A genome-wide CRISPR/Cas9 screen identifies genes that regulate the cellular uptake of α-synuclein fibrils by modulating heparan sulfate proteoglycans

Vanderperre, B.; Muraleedharan, A.; Dorion, M.-F.; Larroquette, F.; Del Cid Pellitero, E.; Rajakulendran, N.; Chen, C. X.- Q.; Lariviere, R.; Michaud-Tardif, C.; Chidiac, R.; Lipuma, D.; Macleod, G.; Thomas, R.; Wang, Z.; Reintsch, W. E.; Luo, W.; Shlaifer, I.; Zhang, F.; Xia, K.; Steinhart, Z.; Linhardt, R. J.; Trempe, J.-F.; Liu, J.; Durcan, T.; Angers, S.; Fon, E. A.

10.1101/2023.09.29.560170 — cell biology — Posted on 2024-07-09

3748 Bridging model and experiment in systems neuroscience with Cleo: the Closed-Loop, Electrophysiology, and Optophysiology simulation testbed

Johnsen, K. A.; Cruzado, N. A.; Menard, Z. C.; Willats, A. A.; Charles, A. S.; Markowitz, J. E.; Rozell, C. J.

10.1101/2023.01.27.525963 — neuroscience — Posted on 2024-07-09

3749 Impact of analytic decisions on test-retest reliability of individual and group estimates in functional magnetic resonance imaging: a multiverse analysis using the monetary incentive delay task

Demidenko, M. I.; Mumford, J. A.; Poldrack, R. A.

10.1101/2024.03.19.585755 — neuroscience — Posted on 2024-07-09

3750 Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe

Donkels, C.; Huber, S.; Demerath, T.; Scheiwe, C.; Schah, M. J.; Heers, M.; Urbach, H.; Schulze-Bonhage, A.; Prinz, M.; Haeussler, U.; Vlachos, A.; Beck, J.; Nakagawa, J. M.; Haas, C. A.

10.1101/2024.03.02.582894 — neuroscience — Posted on 2024-07-09

3751 Selective Functional Connectivity between Ocular Dominance Columns in the Primary Visual Cortex

Aganj, I.; Nasr, S.

10.1101/2024.05.22.595395 — neuroscience — Posted on 2024-07-09

3752 DNA Origami Signal Amplification in LateralFlow Immunoassays

Ijäs, H.; Trommler, J.; Nguyen, L.; van Rest, S.; Nickels, P. C.; Liedl, T.; Urban, M. J.

10.1101/2024.07.05.602214 — biophysics — Posted on 2024-07-09

3753 A coarse-grained model for disordered and multi-domain proteins

Cao, F.; von Bülow, S.; Tesei, G.; Lindorff-Larsen, K.

10.1101/2024.02.03.578735 — biophysics — Posted on 2024-07-09

3754 Assessment of variant effect predictors unveils variants difficulty as a critical performance indicator

Radjasandirane, R.; Diharce, J.; Gelly, J.-C.; de Bervern, A. G.

10.1101/2024.07.08.602580 — bioinformatics — Posted on 2024-07-09

3755 A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery

Hu, X.; Shinn, P.; Itkin, Z.; Lin, Y.; Zhang, Y.-Q.; Shen, M.; Ford-Scheimer, S.; Hall, M. D.

10.1101/2024.04.21.590471 — bioinformatics — Posted on 2024-07-09

3756 Analysis of single-cell CRISPR perturbations indicates that enhancers act multiplicatively and provides limited evidence for epistatic-like interactions

Zhou, J. L.; Guruvayurappan, K.; Toneyan, S.; Chen, H. V.; Chen, A. R.; Koo, P.; McVicker, G. P.

10.1101/2023.04.26.538501 — bioinformatics — Posted on 2024-07-09

3757 Enhancing predictions of protein stability changes induced by single mutations using MSA-based Language Models

Cuturello, F.; Celoria, M.; Ansuini, A.; Cazzaniga, A.

10.1101/2024.04.11.589002 — bioinformatics — Posted on 2024-07-09

3758 Cell Simulation as Cell Segmentation

Jones, D. C.; Elz, A. E.; Hadadianpour, A.; Ryu, H.; Glass, D. R.; Newell, E. W.

10.1101/2024.04.25.591218 — bioinformatics — Posted on 2024-07-09

3759 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design

Trygoniaris, D.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.

10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-07-09

3760 Comparison and benchmark of deep learning methods for non-coding RNA classification

Creux, C.; Zehraoui, F.; Radvanyi, F.; Tahi, F.

10.1101/2023.11.24.568536 — bioinformatics — Posted on 2024-07-09

3761 Modeling neural coding in the auditory brain with high resolution and accuracy

Drakopoulos, F.; Sabesan, S.; Xia, Y.; Fragner, A.; Lesica, N. A.

10.1101/2024.06.17.599294 — bioengineering — Posted on 2024-07-09

3762 Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing

O'Brien, T. J.; Barlow, I. L.; Feriani, L.; Brown, A. E.

10.1101/2023.08.25.554786 — animal behavior and cognition — Posted on 2024-07-09

3763 Repeated horizontal acquisition of lagriamide-producing symbionts in Lagriinae beetles

Uppal, S.; Waterworth, S. C.; Nick, A.; Vogel, H.; Florez, L.; Kaltenpoth, M.; Kwan, J. C.

10.1101/2024.01.23.576914 — genomics — Posted on 2024-07-09

3764 Multilevel gene expression changes inlineages containing adaptive copy numbervariants

Spealman, P.; de Santana, C.; De, T.; Gresham, D.

10.1101/2023.10.20.563336 — genomics — Posted on 2024-07-09

3765 Ruling the unruly: Innovation in ant larval feeding led to increased caste dimorphism and social complexity

Matte, A.; LeBoeuf, A. C.

10.1101/2022.12.08.519655 — evolutionary biology — Posted on 2024-07-09

3766 Gene conversion limits the cost of asexuality in somatically immortal worms

Kershenbaum, S.; Espejo, M. J.; Griffin, A.; Aboobaker, A.

10.1101/2023.03.20.533553 — evolutionary biology — Posted on 2024-07-09

3767 An RNA interference approach for functional studies in the sea urchin and its use in analysis of Nodal signaling gradients

Wilson, K. A.; Manner, C. J.; Miranda, E.; Berrio, A.; Wray, G. A.; McClay, D. R.

10.1101/2024.06.20.599930 — developmental biology — Posted on 2024-07-09

3768 Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.

Reyes Valenzuela, A.; Turner, M.; Markarian, N.; Lachance-Brais, C.; Hanrahan, J. W.; Vali, H.; Vidal, S.; Mongeau, L.

10.1101/2024.07.02.601655 — cell biology — Posted on 2024-07-09

3769 Chromatin endogenous cleavage provides a global view of RNA polymerase II transcription kinetics

VanBelzen, J.; Sakelaris, B.; Brickner, D. G.; Marcou, N.; Riecke, H.; Mangan, N.; Brickner, J. H.

10.1101/2024.07.08.602535 — molecular biology — Posted on 2024-07-09

3770 Tom1p ubiquitin ligase structure, interaction with Spt6p, and function in maintaining normal transcript levels and the stability of chromatin in promoters

Madrigal, J. A.; Schubert, H. L.; Sdano, M. A.; McCullough, L.; Connell, Z.; Formosa, T.; Hill, C. P.

10.1101/2024.07.08.601072 — molecular biology — Posted on 2024-07-09

3771 Humans rationally balance detailed and temporally abstract world models

Kahn, A. E.; Daw, N. D.

10.1101/2023.11.28.569070 — neuroscience — Posted on 2024-07-09

3772 Neural Stem Cell Relay from B1 to B2 cells in the adult mouse Ventricular-Subventricular Zone

Cebrian-Silla, A.; Assis Nascimento, M.; Mancia Leon, W.; Gonzalez-Granero, S.; Romero-Rodriguez, R.; Obernier, K.; Steffen, D. M.; Lim, D. A.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.

10.1101/2024.06.28.600695 — neuroscience — Posted on 2024-07-09

3773 Spatial mRNA expression patterns of orexin receptors in the dorsal hippocampus

Krause, G. M.; Chirich Barreira, L. M.; Albrecht, A.

10.1101/2024.04.15.589483 — neuroscience — Posted on 2024-07-09

3774 A systematic analysis of the joint effects of ganglion cells, lagged LGN cells, and intercortical inhibition on spatiotemporal processing and direction selectivity

Larisch, R.; Hamker, F. H.

10.1101/2024.01.31.578157 — neuroscience — Posted on 2024-07-09

3775 Environment-independent distribution of mutational effects emerges from microscopic epistasis

Ardell, S.; Martsul, A.; Johnson, M. S.; Kryazhimskiy, S.

10.1101/2023.11.18.567655 — systems biology — Posted on 2024-07-09

3776 Targeting NRP1 with EG00229 induces neurovascular permeability

Dragoni, S.; Brash, J. T.; Fantin, A.; Burridge, C.; Denti, L.; Turowski, P.; Ruhrberg, C.

10.1101/2023.11.07.564946 — physiology — Posted on 2024-07-09

3777 The interplay between biomolecular assembly and phase separation

Bartolucci, G.; Haugerud, I. S.; Michaels, T. C. T.; Weber, C. A.

10.1101/2023.04.18.537072 — biophysics — Posted on 2024-07-09

3778 scKEPLM: Knowledge enhanced large-scale pre-trained language model for single-cell transcriptomics

Li, Y.; Qiao, G.; Wang, G.

10.1101/2024.07.09.602633 — bioinformatics — Posted on 2024-07-09

3779 Effect of a LINE1 DNA sequence on expression of long human genes

Brown, J. C.

10.1101/2023.11.21.568109 — genomics — Posted on 2024-07-09

3780 Household level insecticide deployments (micro-mosaics) for insecticide resistance management: Evaluating deliberate and accidental deployments

Hobbs, N. P.; Hastings, I.

10.1101/2024.07.05.602220 — evolutionary biology — Posted on 2024-07-09

3781 ESRP2-microRNA-122 axis directs the postnatal onset of liver polyploidization and maturation

Bangru, S.; Chen, J.; Baker, N. J.; Das, D.; Chembazhi, U. V.; Derham, J. M.; Chorghade, S. G.; Arif, W.; Alencastro, F.; Duncan, A. W.; Carstens, R. P.; Kalsotra, A.

10.1101/2024.07.06.602336 — developmental biology — Posted on 2024-07-09

3782 Peculiar transcriptional reprogramming with functional impairment of dendritic cells upon exposure to transformed HTLV-1-infected cells

Carcone, A.; Mortreux, F.; Alais, S.; Mathieu, C.; Journo, C.; DUTARTRE, H.

10.1101/2024.05.21.592359 — microbiology — Posted on 2024-07-09

3783 Glutamate is a key nutrient for Porphyromonas gingivalis growth and survival during intracellular autophagic life under nutritionally limited conditions

Chowdhury, N.; Wellslager, B.; Lee, H.; Gilbert, J. L.; Yilmaz, O.

10.1101/2024.07.08.602514 — microbiology — Posted on 2024-07-09

3784 O-glycosylation of intrinsically disordered regions regulates homeostasis of membrane proteins in streptococci

Rahman, M. M.; Zamakhaeva, S.; Rush, J. S.; Chaton, C. T.; Kenner, C. W.; Hla, Y. M.; Tsui, H.-C. T.; Uversky, V. N.; Winkler, M. E.; Korotkov, K. V.; Korotkova, N.

10.1101/2024.05.05.592596 — microbiology — Posted on 2024-07-09

3785 Taxonomy, nomenclature, and identification of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)

Williamson, J. L.; Gadek, C. R.; Robinson, B. W.; Bautista, E.; Bauernfeind, S. M.; Baumann, M. J.; Gyllenhaal, E. F.; Marra, P. P.; Ricote, N.; Singh, N. D.; Valqui, T.; Witt, C. C.

10.1101/2024.07.03.601580 — zoology — Posted on 2024-07-09

3786 In-silico studies on structural and thermodynamics basis of interaction of lac repressor protein binding to different DNA operators

Das, S.

10.1101/2024.07.07.602393 — biophysics — Posted on 2024-07-09

3787 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.

10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-07-09

3788 Behavioral and neural correlates of social hierarchy formation in a sex-changing fish

Quertermous, H. M.; Kamstra, K.; van der Burg, C. A.; Muncaster, S.; Todd, E. V.; Jasoni, C. L.; Brown, C.; Gemmell, N. J.

10.1101/2024.07.04.602141 — animal behavior and cognition — Posted on 2024-07-09

3789 Gut microbiota regulates food intake in a rodent model of binge-eating disorder

Demangeat, T.; Loison, L.; Hure, M.; do Rego, J.-L.; Dechelotte, P.; Achamrah, N.; Coëffier, M.; Ribet, D.

10.1101/2024.07.05.602243 — animal behavior and cognition — Posted on 2024-07-09

3790 Combinations of Insecticide-Treated Nets and Indoor Residual Spraying for Insecticide Resistance Management: A Modelling Exploration

Hobbs, N. P.; Hastings, I.

10.1101/2024.07.05.602226 — evolutionary biology — Posted on 2024-07-09

3791 How Clustering Promotes Biodiversity: A Solution to the Plankton Paradox

Huruntz, K. K.; Ghukasyan, L. E.; Gevorgyan, G. A.

10.1101/2023.12.17.572061 — ecology — Posted on 2024-07-09

3792 Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

Ma, X.; Meng, L.; Zhang, Y.; Xu, T.; Zhou, X.; Qian, M.; Yang, Z.; Han, X.

10.1101/2023.10.02.560590 — microbiology — Posted on 2024-07-09

3793 Legionella felix sp. - A novel Legionella species isolated in Israel from hot tap water

Zizelski Valenci, G.; Ohad, S.; Robinstein, M.; Assaly, S.; Kutikov, I.; Groisman, L.; Murik, O.; Zeevi, D. A.; Ben David, R.; Farber, A.; Dveyrin, Z.; Rorman, E.; Nissan, I.

10.1101/2023.09.14.557692 — microbiology — Posted on 2024-07-09

3794 Antimicrobial mechanism of in-situ plasma activated water treatment of pathogenic Escherichia coli and Staphylococcus aureus biofilms

Xia, B.; Vyas, H. K. N.; Rice, S. A.; Newsome, T. P.; Cullen, P. J.; Mai-Prochnow, A.

10.1101/2024.07.07.602420 — microbiology — Posted on 2024-07-09

3795 Unbiased multiplex antigen screening of Cerebrospinal Fluid detects microbial and autoantigenic epitopes associated with Multiple Sclerosis

Barton, N. J.; Tran, K.; Olson, M. N.; Deshpande, M.; Radu, I.; Francis, N.; Kurban, M.; Orszulak, A. R.; Chigas, S. M.; Sundstrom, J.; Dawes, P.; Murray, L. F.; Ionete, C.; Lim, E. T.; Hemond, C. C.; Chan, Y.

10.1101/2024.07.05.602301 — immunology — Posted on 2024-07-09

3796 A Systematic Review of the Neuroprotective Role and Biomarker Potential of GDF15 in Neurodegeneration

Isik, F. I.; Thomson, S.; Cueto, J. F.; Spathos, J.; Breit, S. N.; Tsai, V. W. W.; Brown, D. A.; Finney, C. A.

10.1101/2024.07.07.600156 — neuroscience — Posted on 2024-07-09

3797 Advancing Thalamic Nuclei Segmentation: The Impact of Compressed Sensing and FastSurfer on MRI Processing

Hubner, S.; Tambalo, S.; Hilbert, T.; Kober, T.; Jovicich, J.

10.1101/2024.07.05.602237 — neuroscience — Posted on 2024-07-09

3798 Probing tau citrullination in Alzheimer's disease brains and mouse models of tauopathy

Liang, H.; Hunt, J. B.; Ma, C.; Kovalenko, A.; Calahatian, J. T.; Pedersen, C.; Liu, H.; Serrano, M. E.; Blazier, D.; Watler, M.; Rocha-Rangel, P.; Saunders, C.; Blair, L. J.; Breydo, L.; Nash, K.; Quadri, Z.; Kraemer, B.; Nelson, P.; Norris, C.; Abner, E. L.; Uversky, V. N.; Chaput, D.; Selenica, M.-L. B.; Lee, D. C.

10.1101/2024.07.06.601399 — neuroscience — Posted on 2024-07-09

3799 Spiking network model of the cerebellum as a reinforcement learning machine

Kuriyama, R.; Yoshimura, H.; Yamazaki, T.

10.1101/2024.06.23.600300 — neuroscience — Posted on 2024-07-09

3800 Additive effects of cerebrovascular disease functional connectome phenotype and plasma p-tau181 on longitudinal neurodegeneration and cognitive outcomes

Chong, J. S. X.; Ji, F.; Hilal, S.; Chong, J. R.; Lau, J. M.; Tong, N. R. J.; Tan, B. Y.; Venketasubramanian, N.; Lai, M. K. P.; Chen, C. L.-H.; Zhou, J. H.

10.1101/2024.07.09.602637 — neuroscience — Posted on 2024-07-09

3801 Representation of visual uniformity in the lateral prefrontal cortex

Ge, Y.; Taschereau-Dumouchel, V.; Lin, Q.; Moharramipour, A.; Sun, Z.; Lau, H.

10.1101/2024.07.07.602149 — neuroscience — Posted on 2024-07-09

3802 GPT-3 reveals selective insensitivity to global vs. local linguistic context in speech produced by treatment-naive patients with positive thought disorder

Sharpe, V.; MacKinley, M.; Nour Eddine, S.; Wang, L.; Palaniyappan, L.; Kuperberg, G. R.

10.1101/2024.07.08.602512 — neuroscience — Posted on 2024-07-09

3803 Picobiinae mites (Acariformes: Syringophilidae) parasitizing the Starlings (Passeriformes: Sturnidae) in the Afrotropical region

Patan, M.; Skoracki, M.; Marcisova, I.; Hromada, M.; Sikora, B.

10.1101/2024.07.09.602639 — zoology — Posted on 2024-07-09

3804 Exploring The Association of Student Perceptions of Their Teachers' Science Instruction and Emotional Engagement and The Variance between Grade Level

Xia, X.; Tai, R. H.

10.1101/2024.07.05.602269 — scientific communication and education — Posted on 2024-07-09

3805 Membrane Contact Sites Between Chloroplasts and Pathogen Interface Underpin Plant Focal Immune Responses

Yuen, E. L. H.; Savage, Z.; Adamkova, V.; Vuolo, C.; Zhou, Y.; Tumtas, Y.; Erickson, J. L.; Prautsch, J.; Balmez, A. I.; Stuttmann, J.; Duggan, C.; Rivetti, F.; Molinari, C.; Schattat, M.; Bozkurt, T. O.

10.1101/2021.10.08.463641 — plant biology — Posted on 2024-07-09

3806 Deletion of Nrf1 exacerbates oxidative stress-induced cellular senescence by disrupting the cell homeostasis

Lyu, D.; Wang, M.; Qiu, L.; Hu, S.; Zhang, Y.

10.1101/2024.03.09.584196 — biochemistry — Posted on 2024-07-09

3807 Comparative vitreous proteomic profiling of proliferative diabetic retinopathy and diabetic with no-retinopathy subjects implicates impaired autophagy in DR pathogenesis

Sharma, S.; Hameed, S. S.; Vishwakarma, S.; Chhablani, J.; Tyagi, M.; Narayanan, R.; Pappuru, R. R.; Swarup, G.; Chakrabarti, S.; Kaur, I.

10.1101/2024.07.08.601678 — genomics — Posted on 2024-07-09

3808 Sex-dependent effects of infection on guppy reproductive fitness and offspring parasite resistance

Weiler, I. L. G.; Kramp, R. D.; Rovenolt, F.; Stephenson, J. F.

10.1101/2023.10.29.564622 — ecology — Posted on 2024-07-09

3809 Integrative, Segregative, and Degenerate Harmonics of the Structural Connectome

Sipes, B. S.; Nagarajan, S.; Raj, A.

10.1101/2024.02.23.581784 — neuroscience — Posted on 2024-07-09

3810 Sleep and circadian rhythm activity alterations during adolescence in a mouse model of neonatal fentanyl withdrawal syndrome

Williams, B.; Gamble, M. C.; Singh, N.; Bryant, C. D.; Logan, B. A.; Logan, R. W.

10.1101/2024.07.05.602239 — neuroscience — Posted on 2024-07-09

3811 Model-guided design of microRNA-based gene circuits supports precise dosage of transgenic cargoes into diverse primary cells

Love, K. S.; Johnstone, C. P.; Peterman, E. L.; Gaglione, S.; Galloway, K. E.

10.1101/2024.06.25.600629 — synthetic biology — Posted on 2024-07-09

3812 Stat3 mediates Fyn kinase driven dopaminergic neurodegeneration and microglia activation

Siddiqui, S.; Liu, F.; Kanthasamy, A. G.; McGrail, M.

10.1101/2024.07.05.602238 — developmental biology — Posted on 2024-07-09

3813 Physiologically refined cell culture conditions uncover oncogene-dependent metabolic signatures in Ewing sarcoma spheroids

Ceranski, A. K.; Carreno-Gonzalez, M. J.; Ehlers, A. C.; Kolodynska, Z.; Vinca, E.; Faehling, T.; Hanssen, K. M.; Poeller, P.; Ohmura, S.; Cidre-Aranaz, F.; Schulze, A.; Gruenewald, T. G. P.

10.1101/2024.07.05.602211 — cancer biology — Posted on 2024-07-09

3814 TSS-Captur: A User-Friendly Characterization Pipeline for Transcribed but Unclassified RNA transcripts

Witte Paz, M. A.; Vogel, T.; Nieselt, K.

10.1101/2024.07.05.602221 — bioinformatics — Posted on 2024-07-09

3815 A microvascularized in vitro liver model for disease modeling and drug discovery

Bonanini, F.; Dinkelberg, R.; Torregrosa, M. C.; Kortekaas, N.; Hagens, T. M. S.; Treillard, S.; Kurek, D.; van Duinen, V.; Vulto, P.; Bircsak, K.

10.1101/2024.07.05.602196 — bioengineering — Posted on 2024-07-09

3816 Forest edges and other semi-natural habitat edges increase wild bee species richness and habitat connectivity in intensively managed temperate landscapes.

Sydenham, M. A. K.; Nielsen, A.; Dupont, Y. L.; Rasmussen, C.; Madsen, H. B.; Torvanger, M. S.; Star, B.

10.1101/2024.07.05.602209 — ecology — Posted on 2024-07-09

3817 Clathrin-associated carriers enable recycling through a kiss-and-run mechanism

Xu, J.; Liang, Y.; Li, N.; Dang, S.; Jiang, A.; Liu, Y.; Guo, Y.; Yang, X.; Yuan, Y.; Zhang, X.; Yang, Y.; Du, Y.; Shi, A.; Liu, X.; Li, D.; He, K.

10.1101/2024.07.09.601372 — cell biology — Posted on 2024-07-09

3818 Decision-making shapes dynamic inter-areal communication within macaque ventral frontal cortex

Stoll, F. M.; Rudebeck, P. M.

10.1101/2024.07.05.602229 — neuroscience — Posted on 2024-07-09

3819 The biomechanical state of the effector affects motor control and provides measures of single trial inhibition in a stop signal task

Ramawat, S.; Marc, I. B.; Di Bello, F.; Bardella, G.; Ferraina, S.; Pani, P.; Brunamonti, E.

10.1101/2024.07.05.602195 — neuroscience — Posted on 2024-07-09

3820 Structured neural fluctuations can generate noise invariance and inter-areal gating at distinct timescales

Montijn, J. S.; Heimel, J. A.

10.1101/2024.07.05.602210 — neuroscience — Posted on 2024-07-09

3821 Cell segmentation without annotation by unsupervised domain adaptation based on cooperative self-learning

Miyaki, S.; Nishimoto, S.; Tokuoka, Y.; Yamada, T. G.; Morikura, T.; Funahashi, A.

10.1101/2024.07.05.602197 — systems biology — Posted on 2024-07-09

3822 Potato cultivars use different root physiological and molecular mechanisms to acclimate to salt stress

Nicolas, M.; Bouma, J.; Venema, J. H.; Van der Schoot, H.; Verstappen, F.; De Zeeuw, T.; Langedijk, S. E.; Boer, D.; Bucher, J.; Staal, M.; Krom, B.; Elzenga, J. T. M.; Visser, R.; Testerink, C.; Karlova, R.

10.1101/2024.07.05.602205 — plant biology — Posted on 2024-07-09

3823 Airway smooth muscle tone curbs hyperresponsiveness in experimental asthma

Gazzola, M.; Boucher, M.; Henry, C.; Rojas-Ruiz, A.; Marsolais, D.; Bosse, Y.

10.1101/2024.07.05.602208 — physiology — Posted on 2024-07-09

3824 Modeling Immunoglobulin light chain amyloidosis in Caenorhabditis elegans

Romeo, M.; Barzago, M. M.; Corbelli, A.; Maglioni, S.; Ventura, N.; Natale, C.; Conz, A.; Salmona, M.; Palladini, G.; Nuvolone, M.; Fiordaliso, F.; Merlini, G.; Diomede, L.

10.1101/2024.07.05.602215 — pathology — Posted on 2024-07-09

3825 Diverse effects of fluorescent labels on alpha-synuclein condensate formation during liquid-liquid phase separation

Ziaunys, M.; Sulskis, D.; Veiveris, D.; Sakalauskas, A.; Mikalauskaite, K.; Smirnovas, V.

10.1101/2024.07.05.602219 — biophysics — Posted on 2024-07-09

3826 Uncertainty-Aware Traction Force Microscopy

Kandasamy, A.; Yeh, Y.-T.; Serrano, R.; Mercola, M.; del Alamo, J. C.

10.1101/2024.07.05.602172 — biophysics — Posted on 2024-07-09

3827 VirID: Beyond Virus Discovery - An Integrated Platform for Comprehensive RNA Virus Characterization

Yang, Z.; Shan, Y.; Liu, X.; Chen, G.; Pan, Y.; Gou, Q.; Zou, J.; Chang, Z.; Zeng, Q.; Yang, C.; Kong, J.; Sun, Y.; Li, S.; Zhang, X.; Wu, W.; Li, C.; Peng, H.; Holmes, E. C.; Guo, D.; Shi, M.

10.1101/2024.07.05.602175 — bioinformatics — Posted on 2024-07-09

3828 Interpretable variational encoding of genotypes identifiescomprehensive clonality and lineages in single cells geometrically

Chung, H. M.; Huang, Y.

10.1101/2024.07.04.602109 — genomics — Posted on 2024-07-09

3829 Drivers of recovery and degradation of riverine benthic macroinvertebrate communities: A nationwide analysis of time series

Schuerings, C.; Kaijser, W.; Gillmann, S. M.; Peters, K.; Kiesel, J.; Lorenz, A. W.; Hering, D.

10.1101/2024.07.05.602183 — ecology — Posted on 2024-07-09

3830 Soil microbial responses to multiple global change factors as assessed by metagenomics

Rodriguez del Rio, A.; Rillig, M. C.

10.1101/2024.07.05.602153 — ecology — Posted on 2024-07-09

3831 Somatic Cell Identity Affects Specific Cell Differentiation Programs Upon Reprogramming In Vivo

Zikmund, T.; Fiorentino, J.; Penfold, C. A.; Stock, M.; Agarwal, G.; Langfeld, L.; Hamperl, S.; Scialdone, A.; Hoermanseder, E.

10.1101/2024.07.05.602198 — developmental biology — Posted on 2024-07-09

3832 LAG-3 blockade reactivates the CD8+ T cell expansion program to re-expand contracted clones in the tumor

Takahashi, M.; Tsunoda, M.; Aoki, H.; Kurosu, M.; Ogiwara, H.; Shichino, S.; Bending, D.; Ishikawa, S.; Thaventhiran, J.; Matsushima, K.; Ueha, S.

10.1101/2024.07.05.601623 — immunology — Posted on 2024-07-09

3833 Tau phosphorylation suppresses oxidative stress-induced mitophagy via FKBP8 receptor modulation

Isei, M. O.; Crockett, M.; Chen, E.; Rodwell-Bullock, J.; Caroll, T.; Girardi, P. A.; Nehrke, K.; Johnson, G. V.

10.1101/2024.07.05.602170 — neuroscience — Posted on 2024-07-09

3834 Pharmacological rescue of motor circuit dysfunction in a Drosophila model of paroxysmal dyskinesia

Wilson, A.; Jiang, Y.; Desai, N.; Simon-Batsford, N.; Sanderson, A.; Tolley, I.; Gao, H.; Jepson, J.

10.1101/2024.07.05.602188 — neuroscience — Posted on 2024-07-09

3835 Frontal Theta Oscillations and Cognitive Flexibility: Age-Related Modulations in EEG Activity

Darna, M.; Stolz, C.; Jauch, H. S.; Strumpf, H.; Hopf, J. M.; Seidenbecher, C. I.; Schott, B. H.; Richter, A.

10.1101/2024.07.05.602082 — neuroscience — Posted on 2024-07-09

3836 Novel quantal analysis method reveals conservation of injected charge by excitatory synapses across cortical cells of different sizes

Dervinis, M.; Major, G.

10.1101/2024.07.05.602190 — neuroscience — Posted on 2024-07-09

3837 Tabula Glycine: The whole-soybean single-cell resolution transcriptome atlas

Cervantes-Perez, S. A.; Thibivilliers, S.; Amini, S.; Pelletier, J. M.; Meyer, I.; Xu, H.; Tennant, S.; Ma, P.; Sprueill, C. M.; Farmer, A. D.; Coate, J.; Nelissen, H.; Yao, Q.; Martin, O.; Amezquita, E. J.; Goldberg, R.; Harada, J.; Libault, M.

10.1101/2024.07.08.602332 — plant biology — Posted on 2024-07-09

3838 Exercise and disease state influence the beneficial effects of Fn14-depletion on survival and muscle pathology in the SOD1G93A amyotrophic lateral sclerosis (ALS) mouse model

Hazell, G.; Ahlskog, N.; Sutton, E. R.; Okoh, M.; Hoolachan, J. M.; Scaife, T.; Iqbal, S.; McCallion, E.; Bhomra, A.; Kordala, A. J.; Scamps, F.; Raoul, C.; Wood, M. J.; Bowerman, M.

10.1101/2024.07.05.602199 — pathology — Posted on 2024-07-09

3839 scTail: precise polyadenylation site detection and its alternative usage analysis from reads 1 preserved 3' scRNA-seq data

Hou, R.; Huang, Y.

10.1101/2024.07.05.602174 — bioinformatics — Posted on 2024-07-09

3840 Reconstructing the evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene

Bohlen, V. S.; Dvorak, T.; Freyhof, J.; Kottelat, M.; Levin, B.; Golubtsov, A.; Slechta, V.; Bohlen, J.

10.1101/2024.07.05.602185 — evolutionary biology — Posted on 2024-07-09

3841 Selective promotion of oligonucleotides in the course of evolution

Mathew, B.; Halder, A.; Panda, S.; Jaiswal, N.; Pramanik, D.; Peela, S. C. M.; Garg, A.; Tripathi, S.; Gupta, P.; Malhotra, V.; Ahuja, G.; Sengupta, D.

10.1101/2024.07.05.602168 — evolutionary biology — Posted on 2024-07-09

3842 Spectral algal fingerprinting and long sequencing in synthetic algal-microbial communities

Meirkhanova, A.; Marks, S.; Feja, N.; Vorobjev, I. A.; Barteneva, N. S.

10.1101/2024.07.08.602014 — ecology — Posted on 2024-07-09

3843 Physiological Roles of an Acinetobacter-specific σ Factor

Bacon, E. E.; Myers, K. S.; Iruegas-Lopez, R.; Banta, A. B.; Place, M.; Ebersberger, I.; Peters, J. M.

10.1101/2024.07.08.602572 — microbiology — Posted on 2024-07-09

3844 Age-related differences in working memory subprocesses decomposed by the reference-back paradigm

Gaal, Z. A.; Nagy, B.; Czigler, I.; Csizmadia, P.; Petro, B.; Kojouharova, P.

10.1101/2024.07.04.602161 — neuroscience — Posted on 2024-07-09

3845 Structurally targeted mutagenesis identifies key residues supporting α-synuclein misfolding in multiple system atrophy

Reis, P. M.; Holec, S. A. M.; Ezeiruaku, C.; Frost, M. P.; Brown, C. K.; Liu, S. L.; Olson, S. H.; Woerman, A. L.

10.1101/2024.07.04.602104 — neuroscience — Posted on 2024-07-09

3846 Population connective field modeling reveals retinotopic visual cortex organization in the prenatal human brain

Yoo, S.-H.; Kieslinger, A.-S.; Skeide, M. A.

10.1101/2024.07.08.602507 — neuroscience — Posted on 2024-07-08

3847 Humans forage for reward in reinforcement learning tasks

Zid, M.; Laurie, V.-J.; Levine-Champagne, A.; Shourkeshti, A.; Harrel, D.; Herman, A.; Ebitz, B.

10.1101/2024.07.08.602539 — neuroscience — Posted on 2024-07-08

3848 Default Mode Network activation at task switches reflects mental task-set structure

Zhou, A. X.; Duncan, J.; Mitchell, D. J.

10.1101/2024.07.08.602546 — neuroscience — Posted on 2024-07-08

3849 Beta-frequency sensory stimulation enhances gait rhythmicity through strengthened coupling between striatal networks and stepping movement

Sridhar, S.; Lowet, E.; Gritton, H.; Freire, J.; Zhou, C.; Liang, F.; Han, X.

10.1101/2024.07.07.602408 — neuroscience — Posted on 2024-07-08

3850 Cerebellar output neurons impair non-motor behaviors by altering development of extracerebellar connectivity

Lee, A. S.; Arefin, T. M.; Gubanova, A.; Stephen, D.; Liu, Y.; Lao, Z.; Krishnamurthy, A.; De Marco Garcia, N. V.; Heck, D. H.; Zhang, J.; Rajadhyaksha, A. M.; Joyner, A. L.

10.1101/2024.07.08.602496 — neuroscience — Posted on 2024-07-08

3851 Pre-cancerous Niche Remodelling Dictates Nascent Tumour Survival

Skrupskelyte, G.; Rojo Arias, J. E.; Dang, Y.; Han, S.; Bejar, M. T.; Colom, B.; Fowler, J. C.; Jones, P.; Rulands, S.; Simons, B. D.; Alcolea, M.

10.1101/2024.07.04.602022 — cancer biology — Posted on 2024-07-08

3852 Cell sorting based on single nucleotide variation enables characterization of mutation-dependent transcriptome and chromatin states.

Salatino, R.; Franco, M.; Romero-Toledo, A.; Wang, Y.; Tsuda, S.; Szentirmai, O.; Janiszewska, M.

10.1101/2024.07.05.602247 — cancer biology — Posted on 2024-07-08

3853 Promoting enzyme catalysis via azobenzene facilitated vibrational energy transfer

Lahmy, R.; Hiefinger, C.; Zeqiri, F.; Mandl, S.; Straub, K.; Stockerl, W.; Gschwind, R. M.; Rudack, T.; Koenig, B.; Hupfeld, A.

10.1101/2024.07.04.602025 — biophysics — Posted on 2024-07-08

3854 Transcriptional landscapes underlying Notch-induced lineageconversion and plasticity of mammary basal cells

Merle, C.; Rodrigues, C.; Pourkhalili Langeroudi, A.; Journot, R.; Rost, F.; Dang, Y.; Rulands, S.; Fre, S.

10.1101/2024.07.04.602034 — developmental biology — Posted on 2024-07-08

3855 Genome-wide mapping of autonomously replicating sequences in the marine diatom Phaeodactylum tricornutum

Yun, H.-S.; Yoneda, K.; Sugasawa, T.; Suzuki, I.; Maeda, Y.

10.1101/2024.07.07.602421 — molecular biology — Posted on 2024-07-08

3856 Insights into the RNA virome of the corn leafhopper Dalbulus maidis, a major emergent threat of Maize in Latin America

Debat, H. J.; Farrher, E. S.; Bejerman, N.

10.1101/2024.07.05.602261 — microbiology — Posted on 2024-07-08

3857 Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation

Cakmak, P.; Lun, J. H.; Singh, A.; Macas, J.; Schupp, J.; Koehler, M.; Starzetz, T.; Burger, M. C.; Steidl, E.; Hasse, L. M.; Hattingen, E.; Plate, K. H.; Reiss, Y.; Imkeller, K.

10.1101/2024.07.04.602038 — immunology — Posted on 2024-07-08

3858 Photopharmacological activation of adenosine A1receptor signaling suppresses seizures in a mousemodel for temporal lobe epilepsy

Spanoghe, J.; Boon, P.; Vergaelen, M.; De Colvenaer, M.; Mariman, T.; Vonck, K.; Carrette, E.; Wadman, W.; Craey, E.; Larsen, L. E.; Sprengers, M.; Missinne, J.; Van Calenbergh, S.; De Bundel, D.; Smolders, I.; Raedt, R.

10.1101/2024.07.04.602052 — neuroscience — Posted on 2024-07-08

3859 Calcium-triggered (de)ubiquitination events in synapses

Ainatzi, S.; Kaufmann, S. V.; Silbern, I.; Georgiev, S. V.; Lorenz, S.; Rizzoli, S. O.; Urlaub, H.

10.1101/2024.07.04.602026 — neuroscience — Posted on 2024-07-08

3860 Modelling the spatiotemporal dynamics of senescent cells in wound healing, chronic wounds, and fibrosis

Shanley, D. P.; Chandrasegaran, S.; Sluka, J. P.

10.1101/2024.07.04.602041 — systems biology — Posted on 2024-07-08

3861 Intracellular Protein Editing to Enable Incorporation of Non-Canonical Residues into Endogenous Proteins

Beyer, J.; Serebrenik, Y.; Toy, K.; Najar, M. A.; Raniszewski, N.; Shalem, O.; Burslem, G.

10.1101/2024.07.08.602493 — biochemistry — Posted on 2024-07-08

3862 Discovery and pharmacological characterization of nanobodies acting as potent positive allosteric modulators of the calcium-sensing receptor

Mos, I.; Zögg, T.; Wohlkönig, A.; Egholm, A. M. H.; Rahman, S. N.; Pardon, E.; Steyaert, J.; Bräuner-Osborne, H.; Mathiesen, J. M.

10.1101/2024.07.08.602375 — biochemistry — Posted on 2024-07-08

3863 Effectiveness of CRISPR-Cas in Sensitizing Bacterial Populations with Plasmid-Encoded Antimicrobial Resistance

Kippnich, J.; Benz, F.; Uecker, H.; Baumdicker, F.

10.1101/2024.07.05.602127 — evolutionary biology — Posted on 2024-07-08

3864 Coordination of transcription-coupled repair and repair-independent release of stalled RNA polymerase II in response to transcription-blocking lesions

Zhu, Y.; Zhang, X.; Gao, M.; Huang, Y.; Tan, Y.; Parnas, A.; Wu, S.; Zhan, D.; Adar, S.; Hu, J.

10.1101/2024.07.07.602436 — molecular biology — Posted on 2024-07-08

3865 Long-read RNA sequencing reveals allele-specific N6-methyladenosine modifications

Park, D.; Cenik, C.

10.1101/2024.07.08.602538 — molecular biology — Posted on 2024-07-08

3866 Biotin based Northern Blotting (BiNoB): A Robust and Efficient Alternative

Madhry, D.; Roy, R.; Verma, B.

10.1101/2024.07.08.602531 — molecular biology — Posted on 2024-07-08

3867 Genetic architecture of the tomato fruit lipidome; new insights link lipid and volatile compounds

Kuhalskaya, A.; Li, X.; Lee, J.; Gonda, I.; Nauen, J.; Bulut, M.; Karakas, E.; Fisher, J.; Kraemer, K.; Vanholme, R.; Rosental, L.; Wijesingha Ahchige, M.; Garbowicz, K.; Klemmer, A.; Russ, A.-K.; Donath, A.; Cuadros-Inostroza, A.; Boerjan, W.; Tieman, D.; Zamir, D.; Klee, H.; Alseekh, S.

10.1101/2024.07.08.602461 — molecular biology — Posted on 2024-07-08

3868 Chromatin endogenous cleavage provides a global view of RNA polymerase II transcription kinetics

VanBelzen, J.; Sakelaris, B.; Brickner, D. G.; Marcou, N.; Riecke, H.; Mangan, N.; Brickner, J. H.

10.1101/2024.07.08.602535 — molecular biology — Posted on 2024-07-08

3869 Origin, divergence and migration routes of psyllids of the Cacopsylla pruni complex (Hemiptera: Psylloidea) inferred by Approximate Bayesian Computation methods

Darnis, M.; Ravigne, V.; Sauvion, N.

10.1101/2024.07.08.602570 — molecular biology — Posted on 2024-07-08

3870 RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer

Xie, X.; Macknight, H. P.; Lu, A. L.; Chalfant, C. E.

10.1101/2024.07.08.602494 — molecular biology — Posted on 2024-07-08

3871 A cost-effective and scalable approach for DNA extraction from FFPE tissues

Geisenberger, C.; Chimal, E.; Jurmeister, P.; Klauschen, F.

10.1101/2024.07.08.602387 — molecular biology — Posted on 2024-07-08

3872 Asparagine couples group A Streptococcal metabolism to virulence

Sharma, A.; Anand, A.; Ravins, M.; Horstmann, N. M. M.; McIver, K. S.; Hanski, E.

10.1101/2024.07.08.602371 — microbiology — Posted on 2024-07-08

3873 A pumpless and tubeless microfluidic device enables extended in vitro development of Cryptosporidium parvum

Gunasekera, S.; Thierry, B.; Cheah, E.; King, B.; Monis, P.; Carr, J. M.; Chopra, A.; Watson, M.; O'Dea, M.; Ryan, U.

10.1101/2024.07.07.602413 — microbiology — Posted on 2024-07-08

3874 Improving Mannanase Production in Bacillus subtilis for Fibre Hydrolysis during Solid-State Fermentation of Palm Kernel Meal

Ong, W. L.; Li, Z.; Ng, K. H.; Zhou, K.

10.1101/2024.07.07.602432 — synthetic biology — Posted on 2024-07-08

3875 Nematode Extracellular Protein Interactome Expands Connections between Signaling Pathways

Nawrocka, W. I.; Cheng, S.; Hao, B.; Rosen, M.; Cortes, E.; Baltrusaitis, E.; Aziz, Z.; Kovacs, I. A.; Özkan, E.

10.1101/2024.07.08.602367 — biochemistry — Posted on 2024-07-08

3876 Jasmonic acid signalling is targeted by a smut fungal Tin2-fold effector

Gul, S.; Mendoza-Rojas, G.; Hessler, N.; Galle, S.; Smits, S. H. J.; Altegoer, F.; Gohre, V.

10.1101/2024.07.08.602457 — biochemistry — Posted on 2024-07-08

3877 Plasmid2MC: Efficient cell-free recombination of plasmids into high-purity minicircle DNA for use in genome editing applications

Oliynyk, R. T.; Mahas, A.; Karpinski, E.; Church, G. M.

10.1101/2024.07.08.602524 — genetics — Posted on 2024-07-08

3878 FoldToken3: Fold Structures Worth 256 Words or Less

Gao, Z.; Tan, C.; Li, S. Z.

10.1101/2024.07.08.602548 — molecular biology — Posted on 2024-07-08

3879 Decoding the Escherichia coli epitranscriptome

Riquelme-Barrios, S.; Vasquez Camus, L.; Cusack, S. A.; Burdack, K.; Plamenov Petrov, D.; Yesiltac, G. N.; Kaiser, S.; Giehr, P.; Jung, K.

10.1101/2024.07.08.602490 — microbiology — Posted on 2024-07-08

3880 Casein Kinases 2-dependent phosphorylation of the placental ligand VAR2CSA regulates Plasmodium falciparum-infected erythrocytes cytoadhesion

Dorin-Semblat, D.; Semblat, J.-P.; Hamelin, R.; Srivastava, A.; Tetard, M.; Matesic, G.; Doerig, C.; GAMAIN, B.

10.1101/2024.07.08.602479 — microbiology — Posted on 2024-07-08

3881 Biological tick control: modeling the potential impact of entomopathogenic fungi on the transmission of East Coast fever in cattle

Oundo, J. W.; Hartemink, N.; de Jong, M. C. M.; Koenraadt, C. J. M.; Kalayou, S.; Masiga, D.; ten Bosch, Q.

10.1101/2024.07.08.602534 — microbiology — Posted on 2024-07-08

3882 FapR regulates HssRS-mediated heme homeostasis in Bacillus anthracis

Skaar, E. P.; Pi, H.; Carlin, S. M.; Beavers, W. N.; Hillebrand, G. H.; Krystofiak, E. S.; Stauff, D. L.

10.1101/2024.07.08.602573 — microbiology — Posted on 2024-07-08

3883 MICROBIOTA AT THE CROSS ROAD OF DIET AND HEALTH: HOW DIETARY FATS SHAPE BACTERIAL LAND-SCAPE AND INFLUENCE GLOBAL HEALTH

Portela, N. D.; Eberhardt, N.; Bergero, G.; Mazzocco, Y. L.; Aoki, M. P.; Galvan, C. A.; Cano, R. C.; Pesoa, S. A.

10.1101/2024.07.08.602483 — microbiology — Posted on 2024-07-08

3884 Discordance in Genotypic and Phenotypic anti-tuberculosis drug susceptibility results: time to reconsider critical concentration.

Shrivas, A.; Singh, S.; Singh, J.; Shankar, P.; Soni, P.; Rufai, S. B.; Maurya, A.; Purwar, S.

10.1101/2024.07.08.602571 — microbiology — Posted on 2024-07-08

3885 Mechanistic Insights into MinD Regulation and Pattern Formation in Bacillus subtilis

Feddersen, H.; Bramkamp, M.

10.1101/2024.07.08.602513 — microbiology — Posted on 2024-07-08

3886 Subsurface Microbial Colonization at Mineral-Filled Veins in 2-Billion-Year-Old Igneous Rock from the Bushveld Complex, South Africa

Suzuki, Y.; Webb, S. J.; Kouduka, M.; Kobayashi, H.; Castillo, J. H.; Kallmeyer, J.; Moganedi, K.; Allwright, A. J.; Klemd, R.; Roelofse, F.; Mapiloko, M.; Hill, S. J.; Ashwal, L. D.; Trumbull, R. B.

10.1101/2024.07.08.602455 — microbiology — Posted on 2024-07-08

3887 Typing of feces-derived Candida albicans strains using a novel seven-locus microsatellite panel reveals associations with yeast phenotype in individuals with inflammatory bowel disease

van Thiel, I. A. M.; Kreulen, I. A. M.; Benard, M. V.; de Goffau, M.; Theelen, B.; Heinsbroek, S. E. M.; Zylka, P.; Ponsioen, C. Y.; Boekhout, T.; de Jonge, W. J.; Rosendahl, S.; van den Wijngaard, R. M.; Hagen, F.

10.1101/2024.07.08.601751 — microbiology — Posted on 2024-07-08

3888 EM-Compressor: Electron Microscopy Image Compression in Connectomics with Variational Autoencoders

Li, Y.; Park, C. F.; Xenes, D.; Bishop, C.; Berger, D. R.; Samuel, A. D. T.; Wester, B.; Lichtman, J. W.; Pfister, H.; Li, W.; Meirovitch, Y.

10.1101/2024.07.07.601368 — neuroscience — Posted on 2024-07-08

3889 Astroglial atrophy associates with loss of nuclear S100A10 in the hippocampus of aged male tree shrews

Rodriguez-Callejas, J. d. D.; Irene-Fierro, M.; Aguilar-Navarro, S. G.; Fuchs, E.; Perez-Cruz, C.

10.1101/2024.07.04.602113 — neuroscience — Posted on 2024-07-08

3890 Structural insights into the in situ assembly of clustered protocadherin γB4

Zhang, Z.; Chen, F.; Zhang, Z.; Guo, L.; Feng, T.; Fang, Z.; Xin, L.; Yu, Y.; Hu, H.; He, Y.

10.1101/2024.07.05.602218 — biophysics — Posted on 2024-07-08

3891 BacTermFinder: A Comprehensive and General Bacterial Terminator Finder using a CNN Ensemble

Taheri Ghahfarokhi, S. M. A.; Pena-Castillo, L.

10.1101/2024.07.05.602086 — bioinformatics — Posted on 2024-07-08

3892 DNA walk of specific fused oncogenes exhibit distinct fractal geometric characteristics in nucleotide patterns

Das, A.; Sehgal, M.; Singh, A.; Goyal, R.; Prabhakar, M.; Fricke, J.; Mambetsariev, I.; Kulkarni, P.; Jolly, M. K.; Salgia, R.

10.1101/2024.07.05.602166 — bioinformatics — Posted on 2024-07-08

3893 Activation of two noncanonical R proteins by an insect effector confers plant immunity to aphid infestation

Lei, K.; Tian, D.; Shao, Y.; Wang, F.; Chang, J.; Char, S. N.; Li, G.; Dong, Z.; Zhang, J.; Cui, J.-H.; Zhao, S.; Li, J.; Liu, H.; Liu, G.-Q.; Lv, P.; Wei, M.; Jin, X.; Song, Q.; Yang, B.; Zhang, K.; Wu, D.; Wang, D. W.

10.1101/2024.07.06.601796 — genetics — Posted on 2024-07-08

3894 Independent genetic mapping experiments identify diverse molecular determinants of host adaptation in a generalist herbivore

Villacis-Perez, E.; De Graeve, F.; De Beer, B.; Ali Alshami, S.; de Jong, R.; De Meyer, T.; Van Leeuwen, T.

10.1101/2024.07.05.602111 — evolutionary biology — Posted on 2024-07-08

3895 Abundance, diversity and evolution of tyrosinase enzymes involved in the adhesive systems of mussels and tubeworms

Duthoo, E.; Delroisse, J.; Maldonado, B.; Sinot, F.; Mascolo, C.; Wattiez, R.; Lopez, P. J.; Van de Weerdt, C.; Harrington, M.; Flammang, P.

10.1101/2024.07.05.602216 — evolutionary biology — Posted on 2024-07-08

3896 Fish predation induces drifting and emergence in an experimental stream mesocosm system

Vermiert, A.-M.; Madge Pimentel, I.; Rehsen, P. M.; Meisner, J.; Horstmann, M.; Beermann, A. J.; Leese, F.; Weiss, L. C.; Tollrian, R.

10.1101/2024.07.04.602120 — ecology — Posted on 2024-07-08

3897 Tom1p ubiquitin ligase structure, interaction with Spt6p, and function in maintaining normal transcript levels and the stability of chromatin in promoters

Madrigal, J. A.; Schubert, H. L.; Sdano, M. A.; McCullough, L.; Connell, Z.; Formosa, T.; Hill, C. P.

10.1101/2024.07.08.601072 — molecular biology — Posted on 2024-07-08

3898 SARS-CoV-2 neutralization and protection of hamsters via nasal administration of a humanized neutralizing antibody

Lebedin, M.; Petrovsky, N.; Tabynov, K.; Tabynov, K.; Lebedin, Y.

10.1101/2024.07.08.602557 — immunology — Posted on 2024-07-08

3899 Inclusion of Salicornia ramosissima biomass in diets for juvenile whiteleg shrimp (Penaeus vannamei) induces favourable but transient effects in the immune and oxidative status

Ramos-Pinto, L.; Marcal, R.; Barreto, A.; Laranjeira, A.; Machado, M.; Fernandez-Boo, S.; Teixeira, C.; Couto, A.; Dias, J.; Guilherme, S.; Verissimo, A.; Pinto, D.; Rocha, R.; Costas, B.

10.1101/2024.07.05.602095 — immunology — Posted on 2024-07-08

3900 eLemur: A cellular-resolution 3D atlas of the mouse lemur brain

Jeon, H.; Kim, J.; Kim, J.; Choi, Y. K.; Ho, A. C. L.; Pifferi, F.; Huber, D.; Feng, L.; Kim, J.

10.1101/2024.07.05.601641 — neuroscience — Posted on 2024-07-08

3901 Mutation of phosphatidate phosphohydrolase genes confers broad-spectrum disease resistance in plants

Gong, Q.; Sha, G.; Han, X.; Guo, Z.; Yang, L.; Yang, W.; Tan, R.; Chen, G.; Li, Y.; Shen, X.; Xie, K.; Cai, G.; Hu, H.; Luo, J.; Li, Q.; Li, G.

10.1101/2024.07.04.602136 — plant biology — Posted on 2024-07-08

3902 Assessing nutritional pigment content and plant health status of green and red leafy vegetables by image analysis: Catching the 'red herring' of plant digital color processing

Agarwal, A.; de Jesus Colwell, F.; Correa Galvis, V. A.; Hill, T.; Boonham, N.; Prashar, A.

10.1101/2024.07.04.602112 — plant biology — Posted on 2024-07-08

3903 Hepatic Nrf1 (Nfe2l1) promotes VLDL dependent liver defense against sepsis

Trites, M. J.; Li, L.; Akl, M. G.; Hydomako, A.; Widenmaier, S. B.

10.1101/2024.07.04.602118 — physiology — Posted on 2024-07-08

3904 stormTB: A web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments.

Visintainer, R.; Fochesato, A.; Boaretti, D.; Giampiccolo, S.; Watson, S.; Levi, M.; Reali, F.; Marchetti, L.

10.1101/2024.07.04.602069 — pharmacology and toxicology — Posted on 2024-07-08

3905 Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets

Vijay, V.; Karisani, N.; Shi, L.; Hung, Y.-H.; Vu, P.; Kattel, P.; Kenney, L.; Merritt, J.; Adil, R.; Wu, Q.; Zhen, Y.; Morris, R.; Kreuzer, J.; Kathiresan, M.; Herrera Lopez, X. I.; Ellis, H.; Gritti, I.; Lecorgne, L.; Farag, I.; Popa, A.; Shen, W.; Kato, H.; Xu, Q.; Balasooriya, E. R.; Wu, M.-J.; Chaturantabut, S.; Kelley, R. K.; Cleary, J. M.; Lawrence, M. S.; Root, D. E.; Benes, C. H.; Deshpande, V.; Juric, D.; Ferrone, C. R.; Sellers, W. R.; Haas, W.; Vazquez, F.; Getz, G.; Bardeesy, N.

10.1101/2024.07.04.601970 — cancer biology — Posted on 2024-07-08

3906 UCS: a unified approach to cell segmentation for subcellular spatial transcriptomics

Chen, Y.; Xu, X.; Wan, X.; Xiao, J.; Yang, C.

10.1101/2024.07.08.601384 — bioinformatics — Posted on 2024-07-08

3907 Reinforcement learning guides single-cell sequencing in decoding lineage and cell fate decisions

Fu, Z.; Wang, S.; Sun, K.; Xu, B.; Ye, X.; Wen, Z.; Shen, M.; Chen, M.; Chen, F.; Xu, Y.; Chen, S.; Wang, J.

10.1101/2024.07.04.602019 — bioinformatics — Posted on 2024-07-08

3908 Regulation of cell-nanoparticle interactions through mechanobiology

Cassani, M.; Niro, F.; Fernandes, S.; Pereira-Sousa, D.; Morazzo, S.; Durikova, H.; Vrbsky, J.; Oliver-De La Cruz, J.; Klimovic, S.; Pribyl, J.; Loja, T.; Skladal, P.; Caruso, F.; Forte, G.

10.1101/2024.07.07.599665 — bioengineering — Posted on 2024-07-08

3909 Droplet-AI-empowered high-throughput screening of cell-free gene expression

Zhu, J.; Meng, Y.; Gao, W.; Yang, S.; Zhu, W.; Ji, X.; Zhai, X.; Liu, W.; Luo, Y.; Ling, S.; Li, J.; Liu, Y.

10.1101/2024.07.04.602084 — bioengineering — Posted on 2024-07-08

3910 Loss of conserved noncoding elements likely shaped the evolution of regressed phenotypes in cavefish

Lal, M.; Bhattacharya, J.; Sandhu, K. S.

10.1101/2024.07.05.596787 — genomics — Posted on 2024-07-08

3911 NSP4 mutation T492I drives rapid evolution of SARS-CoV-2 toward Omicron

Lin, X.; Sha, Z.; Zhang, C.; Adler, J. M.; Vidal, R. M.; Langner, C.; Fu, B.; Xiong, Y.; Tan, M.; Jiang, C.; Zeng, H.; Zhang, X.; Li, Q.; Yan, J.; Lu, X.; Wang, S.; Mao, X.; Kunec, D.; Trimpert, J.; Wu, H.; Zou, Q.; Zhu, Z.

10.1101/2024.07.05.602217 — evolutionary biology — Posted on 2024-07-08

3912 Landscape conservation and orchard management influence carob tree yield through changes in pollinator communities

Gomez-Martinez, C.; Gonzalez-Estevez, M. A.; deCastro-Arrazola, I.; Unglaub, P.; Lazaro, A.

10.1101/2024.07.05.602169 — ecology — Posted on 2024-07-08

3913 White matter microglia morphological changes with aging in guinea pig offspring born growth restricted

Nunes, T. B.; Nygard, K. L.; Courchesne, M. C. J.; Whitehead, S. N.; Richardson, B. S.; Regnault, T. R. H.

10.1101/2024.07.04.602101 — developmental biology — Posted on 2024-07-08

3914 Early 2022 breakthrough infection sera from India target the conserved cryptic class 5 epitope to counteract immune escape by SARS-CoV-2 variants

Das Jana, I.; Kanjo, K.; Roy, S.; Bhasin, M.; Bhattacharya, S.; Banerjee, I.; Jana, S.; Chatterjee, A.; Chakraborty, A.; Chakraborty, S.; Mukherjee, B.; Varadarajan, R.; Mondal, A.

10.1101/2024.07.08.602485 — molecular biology — Posted on 2024-07-08

3915 Effector T cells in poorly perfused tumor regions exhibit a distinct signature of augmented IFN response and reduced PD-1 expression

Riera-Borrull, M.; Tejedor Vaquero, S.; Cerdan Porqueras, V.; Aramburu, J.; Lopez-Rodriguez, C.

10.1101/2024.07.05.601540 — immunology — Posted on 2024-07-08

3916 Enhancing Perceptual, Attentional, and Working Memory Demands through Variable Practice Schedules: Insights from High-Density EEG Multi-Scale Analyses

Cretton, A.; Schipper, K.; Hassan, M.; Ruggeri, P.; Barral, J.

10.1101/2024.07.04.602126 — neuroscience — Posted on 2024-07-08

3917 Microglial low-affinity FcγR mediates the phagocytic elimination of dopaminergic neurons in Parkinsons disease degeneration

Casanova, P. V.; Saavedra-Lopez, E.; Freitag-Berenguel, I.; Usandizaga, M.; Martinez-Remedios, P.; Gimenez-Montes, C.; Clinton, E.; Roig-Martinez, M.; Cribaro, G. P.; Barcia, C.

10.1101/2024.07.04.602092 — neuroscience — Posted on 2024-07-08

3918 Time-resolved functional connectivity during visuomotor graph learning

Loman, S.; Caciagli, L.; Kahn, A. E.; Szymula, K. P.; Nyema, N.; Bassett, D. S.

10.1101/2024.07.04.602005 — neuroscience — Posted on 2024-07-08

3919 Delayed accumulation of inhibitory input explains gamma frequency variation with changing contrast in an Inhibition Stabilized Network

Krishnakumaran, R.; Pavuluri, A.; Ray, S.

10.1101/2024.07.04.602155 — neuroscience — Posted on 2024-07-08

3920 Characterizing BOLD activation patterns in the human hippocampus with laminar fMRI

Pfaffenrot, V.; Bouyeure, A.; Gomes, C. A.; Kashyap, S.; Axmacher, N.; Norris, D.

10.1101/2024.07.04.602065 — neuroscience — Posted on 2024-07-08

3921 The dynamic gene regulatory landscape of the mouse brain in response to sleep deprivation

Jagannath, A.; Bafna, A.; Dang, Q.; Taylor, L.; Walsh, S.; Sims, D.; George, C.

10.1101/2024.07.04.602083 — neuroscience — Posted on 2024-07-08

3922 MJF-14 proximity ligation assay detects early non-inclusion alpha-synuclein pathology with enhanced specificity and sensitivity

Jensen, N. M.; Fu, Y.; Betzer, C.; Li, H.; Elfarrash, S.; Shaib, A. H.; Krah, D.; Vitic, Z.; Reimer, L.; Gram, H.; Buchman, V.; Denham, M.; Rizzoli, S. O.; Halliday, G. M.; Jensen, P. H.

10.1101/2024.07.08.602186 — neuroscience — Posted on 2024-07-08

3923 A pilot study for deciphering post-translational modifications and proteoforms of tau protein by capillary electrophoresis-mass spectrometry

Fang, F.; Xu, T.; Chien Hagar, H.-T.; Hovde, S.; Kuo, M.-H.; Sun, L.

10.1101/2024.07.04.602093 — systems biology — Posted on 2024-07-08

3924 Unraveling the Link between Nutrition and Metabolic Syndrome Risk through In Silico Dietary Interventions

Alessi, D. S.; McCreery, C. V.; Zomorrodi, A. R.

10.1101/2024.07.04.602078 — systems biology — Posted on 2024-07-08

3925 Characterization of the Cannabis sativa glandular trichome epigenome

Conneely, L. J.; Hurgobin, B.; Ng, S.; Tamiru-Oli, M.; Lewsey, M. G.

10.1101/2024.07.04.602151 — plant biology — Posted on 2024-07-08

3926 Rodent chronic variable stress procedures: a disjunction between stress entity and impact on behaviour

Menzies, J.; Romano, N.

10.1101/2024.07.04.602063 — physiology — Posted on 2024-07-08

3927 Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity.

Sowton, A. P.; Holzner, L. M.; Krause, F. N.; Baxter, R.; Mocciaro, G.; Krzyzanska, D. K.; Minnion, M.; O'Brien, K. A.; Harrop, M. C.; Darwin, P. M.; Thackray, B. D.; Vacca, M.; Feelisch, M.; Griffin, J. L.; Murray, A. J.

10.1101/2024.07.04.602070 — physiology — Posted on 2024-07-08

3928 Antimicrobial cetylpyridinium chloride suppresses mast cell function by targeting tyrosine phosphorylation of Syk kinase

Obeng, B.; Bennett, L. J.; West, B. E.; Wagner, D. J.; Fleming, P. J.; Tasker, M. N.; Lorenger, M. K.; Smith, D. R.; Systuk, T.; Plummer, S. M.; Eom, J.; Paine, M. D.; Frangos, C. T.; Wilczek, M. P.; Shim, J. K.; Maginnis, M. S.; Gosse, J. A.

10.1101/2024.07.04.602096 — pharmacology and toxicology — Posted on 2024-07-08

3929 A Portrait of a Young Fish: Redescription of Pteronisculus gunnari (Nielsen, 1942) from a juvenile specimen from the Early Triassic of East Greenland, with implications for ontogenetic development in early actinopterygians

Cavicchini, I.; Argyriou, T.; Giles, S.

10.1101/2024.07.06.598961 — paleontology — Posted on 2024-07-08

3930 Thickness and quality controlled fabrication of fluorescence-targeted frozen-hydrated lamellae

Boltje, D.; Skoupy, R.; Taisne, C.; Evers, W.; Jakobi, A. J.; Hoogenboom, J.

10.1101/2024.07.04.602102 — biophysics — Posted on 2024-07-08

3931 Developing peptide-based fusion inhibitors as an antiviral strategy utilizing Coronin 1 as a template

Panda, M. S.; Qazi, B.; Vishwakarma, V.; Pattnaik, G. P.; Haldar, S.; Chakraborty, H.

10.1101/2024.07.04.602150 — biophysics — Posted on 2024-07-08

3932 Oxidation-induced structural changes in actin and myosin evaluated by computational simulation, machine learning modeling and high-speed AFM

Matusovsky, O. S.; Elkrief, D.; Cheng, Y.-S.; Rassier, D. E.

10.1101/2024.07.04.600628 — biophysics — Posted on 2024-07-08

3933 Heli-SMACC: Helicase-targeting SMAll Molecule Compound Collection

Martin, H.-J.; Hossain, M. A.; Wellnitz, J.; Kelestemur, E.; Hochuli, J.; Perveen, S.; Arrowsmith, C.; Willson, T. M.; Muratov, E.; Tropsha, A.

10.1101/2024.07.04.602122 — bioinformatics — Posted on 2024-07-08

3934 Exploring Effector Protein Dynamics and Natural Fungicidal Potential in Rice Blast Pathogen Magnaporthe oryzae

Ferdausi, J.; Robin, T. B.; Nasrin, S.; Ahmed, I.; Hossain, T.; Hasan, M. M.; Soaeb, M. H.; Tamim, M. A.; Yeasmin, N. J.; Habiba, U.; Ahmed, N.; Rani, N. A.; Bhuyian, M. S.; Vakare, S. N.; Moin, A. T.; Patil, R. B.; Hossain, M. S.

10.1101/2024.07.04.602162 — bioinformatics — Posted on 2024-07-08

3935 Structural impact of synonymous mutations in six SARS-CoV-2 Variants of Concern

Ziesel, A.; Jabbari, H.

10.1101/2024.07.06.602340 — bioinformatics — Posted on 2024-07-08

3936 Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A

Kourist, R.; Nigl, A.; Delsoglio, V.; Grgic, M.; Malihan-Yap, L.; Myrtollari, K.; Spasic, J.; Winkler, M.; Oberdorfer, G.; Taden, A.; Anic, I.

10.1101/2024.07.04.601532 — bioengineering — Posted on 2024-07-08

3937 Knee Biomechanics during Walking in Individuals with Anterior Cruciate Ligament Repair: The Role of a Custom 3D Printed Knee Brace

Mougin, F.; Begon, M.; Desmyttere., G.; Bleau, J.; Nault, M.-L.; Cherni, Y.

10.1101/2024.07.04.601890 — bioengineering — Posted on 2024-07-08

3938 Targeting prostate cancer by new bispecific monocyte engager directed to prostate-specific membrane antigen

Das, G.; Ptacek, J.; Havlinova, B.; Nedvedova, J.; Barinka, C.; Novakova, Z.

10.1101/2024.07.05.602163 — bioengineering — Posted on 2024-07-08

3939 Behavioral and neural correlates of social hierarchy formation in a sex-changing fish

Quertermous, H. M.; Kamstra, K.; van der Burg, C. A.; Muncaster, S.; Todd, E. V.; Brown, C.; Gemmell, N. J.

10.1101/2024.07.04.602141 — animal behavior and cognition — Posted on 2024-07-08

3940 Identification of significant genome-wide associations and QTL underlying variation in seed protein composition in pea (Pisum sativum L.)

WARSAME, A. O.; Balk, J.; Domoney, C.

10.1101/2024.07.04.602075 — genetics — Posted on 2024-07-08

3941 comparison of genetic diversity and phylogenetic structure of 18S gene of Trichomonas vaginalis in Hainan and Xinjiang provinces

jun, l.

10.1101/2024.07.04.602107 — evolutionary biology — Posted on 2024-07-08

3942 Functional traits explain growth resistance to successive hotter droughts across a wide set of common and future tree species in Europe

Kretz, L.; Schnabel, F.; Richter, R.; Raabgrund, A.; Kattge, J.; Andraczek, K.; Kahl, A.; Kuenne, T.; Wirth, C.

10.1101/2024.07.04.602057 — ecology — Posted on 2024-07-08

3943 S. cerevisiae serves as keystone species for spoilage resistance in experimental synthetic wine yeast communities

Leale, A. M.; Pourcelot, E.; Guezenec, S.; Sicard, D.; Nidelet, T.

10.1101/2024.07.04.602080 — ecology — Posted on 2024-07-08

3944 A Systematic Review of the Distribution and Prevalence of Viruses Detected in the Peromyscus maniculatus Species Complex (Rodentia: Cricetidae)

Finkbeiner, A.; Khatib, A.; Upham, N.; Sterner, B.

10.1101/2024.07.04.602117 — ecology — Posted on 2024-07-08

3945 Deterministic processes played more important roles than stochastic processes in driving community assembly of ectomycorrhizal fungal associated with Pinus tabuliformis - an endemic Pinaceae species in China

Fan, Y.; Yu, Z.; Li, J.; Zhang, X.; Li, M.; Ma, J.; Wang, Y.

10.1101/2024.07.05.602164 — ecology — Posted on 2024-07-08

3946 Control of Modular Tissue Flows Shaping the Embryo in Avian Gastrulation

Serrano Najera, G.; Plum, A. M.; Steventon, B.; Weijer, C. J.; Serra, M.

10.1101/2024.07.04.601785 — developmental biology — Posted on 2024-07-08

3947 Non-muscle myosin 2 can incorporate into established filaments in cells without an assembly competence domain

Wu, K.; Patel, H.; Wu, H.; Quintanilla, M. A.; Bennett, M. A.; Sala, S.; Beach, J. R.

10.1101/2024.07.07.602405 — cell biology — Posted on 2024-07-08

3948 Acidic pH attenuates immune killing through inactivation of perforin

Hodel, A. W.; Rudd-Schmidt, J. A.; Noori, T.; Lupton, C. J.; Cheuk, V. C.; Trapani, J. A.; Hoogenboom, B.; Voskoboinik, I.

10.1101/2024.07.04.602105 — immunology — Posted on 2024-07-08

3949 Macrovascular contributions to resting-state fMRI signals: A comparison between EPI and bSSFP at 9.4 Tesla

Ramadan, D.; Mueller, S.; Stirnberg, R.; Bosch, D.; Ehses, P.; Scheffler, K.; Bause, J.

10.1101/2024.07.04.602062 — neuroscience — Posted on 2024-07-08

3950 The perineurium integrates leptin with its sympathetic outflow to protect against obesity

Sarker, G.; Haberman, E.; Chandran, A.; Monfeuga, T.; Maroteau, C.; Lundh, S.; Raimondi, A.; Martinez Sanchez, N.; Arus, B.; Iannacone, M.; Toledo, E. M.; Domingos, A.

10.1101/2024.07.04.602091 — neuroscience — Posted on 2024-07-08

3951 Infrared thermography for plant stress detection in vertical farms: Investigating spatiotemporal variations and exploring solutions via machine learning

Agarwal, A.; de Jesus Colwell, F.; Dinnis, R.; Correa Galvis, V. A.; Hill, T.; Boonham, N.; Prashar, A.

10.1101/2024.07.04.602094 — plant biology — Posted on 2024-07-08

3952 Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma

Stockmaier, G.; Varkhande, S.; Krenn, P. W.; Dang, H.-h.; Sharma, A.; Elmer, D. P.; Steiner, M.; Zaborsky, N.; Neureiter, D.; Greil, R.; Horejs-Hoeck, J.; Fortelny, N.; Gratz, I. K.; Aberger, F.

10.1101/2024.07.07.602398 — cancer biology — Posted on 2024-07-08

3953 The protease ADAMTS5 controls ovarian cancer cell invasion, downstream of Rab25.

Yuan, S.; Bacchetti, R.; Adams, J. A.; Rainero, E.

10.1101/2024.07.08.602517 — cancer biology — Posted on 2024-07-08

3954 Elraglusib induces cytotoxicity via microtubule destabilisation independently of GSK3 inhibition

Coats, J. T.; Tauro, S.; Sutherland, C.; Saurin, A. T.

10.1101/2024.07.06.602326 — cancer biology — Posted on 2024-07-08

3955 Structural basis for Vipp1 membrane binding: From loose coats and carpetsto ring and rod assemblies

Junglas, B.; Kartte, D.; Kutzner, M.; Hellmann, N.; Ritter, I.; Schneider, D.; Sachse, C.; Sachse, C.

10.1101/2024.07.08.602470 — biophysics — Posted on 2024-07-08

3956 MINFLUX fluorescence nanoscopy in biological tissue

Moosmayer, T.; Kiszka, K. A.; Westphal, V.; Pape, J. K.; Leutenegger, M.; Steffens, H.; Grant, S. G. N.; Sahl, S. J.; Hell, S. W.

10.1101/2024.07.06.602333 — biophysics — Posted on 2024-07-08

3957 Structural plasticity of bacterial ESCRT-III protein PspA in higher-orderassemblies

Junglas, B.; Hudina, E.; Schoennenbeck, P.; Ritter, I.; Heddier, A.; Santiago-Schuebel, B.; Huesgen, P. F.; Schneider, D.; Sachse, C.

10.1101/2024.07.08.602472 — biophysics — Posted on 2024-07-08

3958 Backbone-mediated weakening of pairwise interactions enables percolation in mimics of protein condensates

Zeng, X.; Pappu, R. V.

10.1101/2024.07.08.602299 — biophysics — Posted on 2024-07-08

3959 Much Ado About Nothing: Accelerating Maximum Likelihood Phylogenetic Inference via Early Stopping to evade (Over-)optimization

Togkousidis, A.; Stamatakis, A.; Gascuel, O.

10.1101/2024.07.04.602058 — bioinformatics — Posted on 2024-07-08

3960 Azole resistance: Patterns of amino acid substitutions in Candida sterol 14α-demethylase

Rao, R. S. P.; Pinto, L.; Shastry, R. P.; Dakal, T. C.; Suravajhala, P.; Sashindran, V.; Ghate, S.

10.1101/2024.07.04.602050 — bioinformatics — Posted on 2024-07-08

3961 Activity of FoxP2-positive neurons correlate with tadpole begging behavior

Ludington, S. C.; McKinney, J. E.; Butler, J. M.; Goolsby, B. C.; Callan, A. A.; Gaines-Richardson, M.; O'Connell, L. A.

10.1101/2023.05.26.542531 — animal behavior and cognition — Posted on 2024-07-08

3962 The Pgb1 locus controls glycogen aggregation in astrocytes of the aged hippocampus without impacting cognitive function

Gomez-Pascual, A.; Glikman, D. M.; Ng, H. X.; Tomkins, J. E.; Lu, L.; Xu, Y.; Ashbrook, D. G.; Kaczorowski, C.; Kempermann, G.; Killmar, J.; Mozhui, K.; Ohlenschlaeger, O.; Aebersold, R.; Ingram, D. K.; Williams, E. G.; Williams, R. W.; Overall, R. W.; Jucker, M.; de Bakker, D. E. M.

10.1101/2023.11.22.567373 — genetics — Posted on 2024-07-08

3963 Maximum Likelihood Estimation for Unrooted 3-Leaf Trees: An Analytic Solution for the CFN Model

Hill, M.; Roch, S.; Rodriguez, J. I.

10.1101/2024.02.01.578504 — evolutionary biology — Posted on 2024-07-08

3964 Seasonal changes in fish eDNA signal vary between contrasting river types

Griffiths, N. P.; Bolland, J. D.; Wright, R. M.; Blabolil, P.; Macarthur, J. A.; Sellers, G. S.; Hänfling, B.

10.1101/2024.07.08.601838 — ecology — Posted on 2024-07-08

3965 Enhanced MC1R-signalling and pH modulation facilitate melanogenesis within late endosomes of BLOC-1-deficient melanocytes

Goff, P. S.; Patel, S.; Carter, T.; Marks, M. S.; Sviderskaya, E. V.

10.1101/2024.07.08.602505 — cell biology — Posted on 2024-07-08

3966 The WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation.

Wu, M.; Marchando, P.; Meyer, K.; Tang, Z.; Woolfson, D. N.; Weiner, O. D.

10.1101/2024.07.08.600855 — cell biology — Posted on 2024-07-08

3967 SRSF2 transcriptional function maintains genome integrity during cell division

Wagner, R. E.; Arnetzl, L.; Britto-Borges, T.; Heit-Mondrzyk, A.; Bakr, A.; Sollier, E.; Panten, J.; Delaunay, S.; Sohn, D.; Schmezer, P.; Odom, D. T.; Mueller-Decker, K.; Plass, C.; Dieterich, C.; Lutsik, P.; Borneloev, S.; Frye, M.

10.1101/2024.07.08.602469 — cell biology — Posted on 2024-07-08

3968 What does your gut tell you? Influences of a zombie-making and generalist fungal entomopathogen on carpenter ant micro- and mycobiota

Vermeulen, S.; Forsman, A. M.; de Bekker, C.

10.1101/2024.05.02.592155 — microbiology — Posted on 2024-07-08

3969 Future movement plans interact in sequential arm movements

Kashefi, M.; Reschechtko, S.; Ariani, G.; Shahbazi, M.; Tan, A.; Diedrichsen, J.; Pruszynski, J. A.

10.1101/2023.05.24.542099 — neuroscience — Posted on 2024-07-08

3970 Developmental and age-related synapse elimination is mediated by glial Croquemort

Jay, T. R.; Kang, Y.; Ouellet-Massicotte, V.; Micael, M. K. B.; Kacouros-Perkins, V. L.; Chen, J.; Sheehan, A.; Freeman, M.

10.1101/2024.06.24.600214 — neuroscience — Posted on 2024-07-08

3971 Light-microscopy based dense connectomic reconstruction of mammalian brain tissue

Tavakoli, M. R.; Lyudchik, J.; Januszewski, M.; Vistunou, V.; Agudelo, N.; Vorlaufer, J.; Sommer, C.; Kreuzinger, C.; Oliveira, B.; Cenameri, A.; Novarino, G.; Jain, V.; Danzl, J. G.

10.1101/2024.03.01.582884 — neuroscience — Posted on 2024-07-08

3972 Miniscope Recording Calcium Signals at Hippocampus of Mice Navigating an Odor Plume

de Souza, F. S.; Williamson, R.; McCullough, C. M.; Teel, A.; Futia, G.; Ma, M.; True, A. C.; Crimaldi, J. P.; Gibson, E. A.; Restrepo, D.

10.1101/2024.06.12.598681 — neuroscience — Posted on 2024-07-08

3973 Dedifferentiation of caudate functional organization is linked to reduced D1 dopamine receptor availability and poorer memory function in aging

Korkki, S. M.; Johansson, J.; Nordin, K.; Pedersen, R.; Backman, L.; Rieckmann, A.; Salami, A.

10.1101/2024.03.18.585623 — neuroscience — Posted on 2024-07-08

3974 Multivariate analysis of multimodal brain structure predicts individual differences in risk and intertemporal preference

Bergstrom, F.; Schu, G.; Lee, S.; Lerman, C.; Kable, J. W.

10.1101/2024.07.04.602046 — neuroscience — Posted on 2024-07-08

3975 The Effect of Arm Restriction on Dynamic Stability and Upper Body Responses to Lateral Loss of Balance During Walking: An Observational Study

Rosenblum, U.; Lavi, A.; Fischer, A.; Parmet, Y.; Haim, A.; Handelzalts, S.

10.1101/2023.09.11.557158 — neuroscience — Posted on 2024-07-08

3976 Contextual Expectations in the Real-World Modulate Low-Frequency Neural Oscillations

Nicholls, V. I.; Krugliak, A.; Alsbury-Nealy, B.; Gramann, K.; Clarke, A.

10.1101/2024.05.30.596613 — neuroscience — Posted on 2024-07-08

3977 Efficient coding explains neural response homeostasis and stimulus-specific adaptation

Young, E. J.; Ahmadian, Y.

10.1101/2023.10.29.564616 — neuroscience — Posted on 2024-07-08

3978 Evidence for low affinity of GABA at the vesicular monoamine transporter VMAT2. Implications for transmitter co-release from dopamine neurons

Limani, F.; Srinivasan, S.; Hanzlova, M.; La Batide-Alanore, S.; Klotz, S.; Hnasko, T. S.; Steinkellner, T.

10.1101/2024.07.04.602053 — neuroscience — Posted on 2024-07-08

3979 Methamphetamine-induced adaptation of learning rate dynamics depend on baseline performance.

Kirschner, H.; Molla, H. M.; Nassar, M. R.; de Wit, H.; Ullsperger, M.

10.1101/2024.07.04.602054 — neuroscience — Posted on 2024-07-08

3980 Dichotomy between extracellular signatures of active dendritic chemical synapses and gap junctions

Sirmaur, R.; Narayanan, R.

10.1101/2024.07.04.602060 — neuroscience — Posted on 2024-07-08

3981 Synaptic plasticity in the medial preoptic area of male mice encodes social experiences with female and regulates behavior toward young

Ito, K.; Sato, K.; Tsuneoka, Y.; Maejima, T.; Okuno, H.; Hamasaki, Y.; Murakawa, S.; Takabayashi, Y.; Yoshihara, C.; Shindo, S.; Uki, H.; Herlitze, S.; Seki, M.; Suzuki, Y.; Sakurai, T.; Kuroda, K. O.; Minami, M.; AMANO, T.

10.1101/2023.10.23.560098 — zoology — Posted on 2024-07-08

3982 Cytokinin-inducible DIRIGENT13 involved in lignan synthesis and ROS accumulation promotes root growth and abiotic stress tolerance in Arabidopsis

Melnikava, A.; Perreau, F.; Paniagua, C.; Cheng, S.-C.; Huang, L.-M.; Ubogoeva, E.; Zemlyanskaya, E.; Yang, Y.-L.; Mouille, G.; Arnaud, D.; Hejatko, J.

10.1101/2024.06.25.600713 — plant biology — Posted on 2024-07-08

3983 Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.

Zuniga, D.; Zoumpoulakis, A.; Veloso, R. F.; Peverini, L.; Shi, S.; Pozza, A.; Kugler, V.; Bonnete, F.; Bouceba, T.; Wagner, R.; Corringer, P.-J.; Fernandes, C. A.; Venien-Bryan, C.

10.1101/2024.02.09.579451 — biophysics — Posted on 2024-07-08

3984 On the pH-dependence of α-synuclein amyloid polymorphism and the role of secondary nucleation in seed-based amyloid propagation

Frey, L.; Ghosh, D.; Qureshi, B. M.; Rhyner, D.; Guerrero-Ferreira, R.; Pokharna, A.; Kwiatkowski, W.; Serdiuk, T.; Picotti, P.; Riek, R.; Greenwald, J.

10.1101/2023.06.25.546428 — biophysics — Posted on 2024-07-08

3985 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K

Zheng, L.; Zhou, B.; Wu, B.; Tan, Y.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Hong, L.

10.1101/2023.10.18.562890 — biophysics — Posted on 2024-07-08

3986 Understanding Cu<+2> binding with DNA: A molecular dynamics study comparing Cu<2+> and Mg<2+> binding to the Dickerson DNA

Sharma, A.; Yadav, H. O. S.; Bandyopadhyay, P.

10.1101/2024.07.04.602035 — biophysics — Posted on 2024-07-08

3987 Quantitative Analysis of Miniature Synaptic Calcium Transients Using Positive Unlabeled Deep Learning

Beaupre, F.; Bilodeau, A.; Wiesner, T.; Leclerc, G.; Lemieux, M.; Nadeau, G.; Castonguay, K.; Fan, B.; Labrecque, S.; Hlozek, R.; De Koninck, P.; Gagne, C.; Lavoie-Cardinal, F.

10.1101/2024.07.04.602047 — bioinformatics — Posted on 2024-07-08

3988 GTalign: High-performance protein structure alignment, superposition, and search

Margelevicius, M.

10.1101/2023.12.18.572167 — bioinformatics — Posted on 2024-07-08

3989 Anti-snake behavior and snake discrimination in vervet monkeys

Schad, L.; van de Waal, E.; Fischer, J.

10.1101/2024.07.04.602064 — animal behavior and cognition — Posted on 2024-07-08

3990 Cockroach social network position does not influence exploration tendency

Louca, V.; Savorelli, S.; Vuorio, N.; Fisher, D. N.

10.1101/2024.04.05.588244 — animal behavior and cognition — Posted on 2024-07-08

3991 Whole-genome phylogenomics of the tinamous (Aves: Tinamidae): comparing gene tree estimation error between BUSCOs and UCEs illuminates rapid divergence with introgression

Musher, L. J.; Catanach, T. A.; Valqui, T.; Brumfield, R. T.; Aleixo, A.; Johnson, K. P.; Weckstein, J. D.

10.1101/2024.01.22.576737 — genomics — Posted on 2024-07-08

3992 Unexpectedly low recombination rates and presence of hotspots in termite genomes

Everitt, T.; Ronneburg, T.; Elsner, D.; Olsson, A.; Liu, Y.; Larva, T.; Korb, J.; Webster, M. T.

10.1101/2024.03.22.586269 — genomics — Posted on 2024-07-08

3993 Predicting species distributions in the open ocean with convolutional neural networks.

Morand, G.; Joly, A.; Rouyer, T.; Lorieul, T.; Barde, J.

10.1101/2023.08.11.551418 — ecology — Posted on 2024-07-08

3994 Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations

van der Veer, B. K.; Chen, L.; Tsaniras, S. C.; Brangers, W.; Chen, Q.; Schroiff, M.; Custers, C.; Kwak, H. H. M.; Khoueiry, R.; Cabrera, R.; Gross, S. S.; Finnell, R. H.; Lei, Y.; Koh, K. P.

10.1101/2024.02.21.581196 — developmental biology — Posted on 2024-07-08

3995 Fully-Automated Multicolour Structured Illumination Module for Super-resolution Microscopy

Wang, H.; Brown, P. T.; Ullom, J.; Shepherd, D. P.; Heintzmann, R. P.; Diederich, B.

10.1101/2024.07.04.601961 — cell biology — Posted on 2024-07-08

3996 Cortistatin exerts an immunomodulatory and neuroprotective role in ischemic stroke

Castillo-Gonzalez, J.; Buscemi, L.; Vargas-Rodriguez, P.; Serrano-Martinez, I.; Forte-Lago, I.; Price-Hirt, M.; Hernandez-Cortes, P.; Hirt, L.; Gonzalez-Rey, E.

10.1101/2024.02.07.579281 — immunology — Posted on 2024-07-08

3997 The ciliary kinesin KIF7 controls the development of the cerebral cortex by acting differentially on SHH-signaling in dorsal and ventral forebrain

PEDRAZA, M.; GRAMPA, V.; SCOTTO-LOMASSESE, S.; PUECH, J.; MUZERELLE, A.; MOHAMMAD, A.; RENIER, N.; METIN, C.; MASSON, J.

10.1101/2024.03.21.586159 — neuroscience — Posted on 2024-07-08

3998 Analytical strength-duration curve for the spiking response of the LIF neuron to an alpha-function-shaped excitatory current pulse

Paraskevov, A.

10.1101/2023.09.05.556358 — neuroscience — Posted on 2024-07-08

3999 Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression

Czekalla, N.; Schröder, A.; Mayer, A. V.; Stierand, J.; Stolz, D. S.; Kube, T.; Korn, C. W.; Wilhelm-Groch, I.; Klein, J. P.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.

10.1101/2024.05.09.593087 — neuroscience — Posted on 2024-07-08

4000 Metacognitive Experiences Track Rational Adaptations in Cognitive Processes

Vermeylen, L.; Braem, S.; Ivanchei, I. I.; Desender, K.; Gonzalez-Garcia, C.; Garcia-Roman, J. M.; Ruz, M.; Notebaert, W.

10.1101/2023.09.26.559523 — neuroscience — Posted on 2024-07-08

4001 A neurotrophin functioning with a Toll regulates structural plasticity in a dopaminergic circuit

SUN, J.; ROJO-CORTES, F. R.; ULIAN-BENITEZ, S.; FORERO, M. G.; LI, G.; SINGH, D.; WANG, X.; CACHERO, S.; MOREIRA, M.; KAVANAGH, D.; JEFFERIS, G. S. X. E.; CROSET, V.; HIDALGO, A.

10.1101/2023.01.04.522695 — neuroscience — Posted on 2024-07-08

4002 A theoretical basis for cell death

Himeoka, Y.; Horiguchi, S. A.; Kobayashi, T. J.

10.1101/2024.03.04.583348 — systems biology — Posted on 2024-07-08

4003 Proteomic and functional comparison between human induced and embryonic stem cells

Brenes, A. J.; Griesser, E.; Sinclair, L. V.; Davidson, L.; Prescott, A. R.; Singh, F.; Hogg, E. K. J.; Espejo-Serrano, C.; Jiang, H.; Yoshikawa, H.; Platani, M.; Swedlow, J.; Cantrell, D. A.; Lamond, A. I.

10.1101/2021.10.20.464767 — systems biology — Posted on 2024-07-08

4004 Novel endogenous engineering platform for robust loading and delivery of functional mRNA by extracellular vesicles

Zickler, A. M.; Liang, X.; Gupta, D.; Mamand, D.; de Luca, M.; Corso, G.; Errichelli, L.; Hean, J.; Sen, T.; Elsharkasy, O. M.; Kamei, N.; Niu, Z.; Zhou, G.; Zhou, H.; Roudi, S.; Wiklander, O. P. B.; Goergens, A.; Nordin, J.; Castilla-Llorente, V.; EL Andaloussi, S.

10.1101/2023.03.17.533081 — bioengineering — Posted on 2024-07-08

4005 Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with severe alcohol use disorder

Leclercq, S.; Ahmed, H.; Amadieu, C.; Petit, G.; Koistinen, V.; Leyrolle, Q.; Poncin, M.; Stärkel, P.; Kok, E.; Karhunen, P. J.; de Timary, P.; Laye, S.; Neyrinck, A. M.; Kärkkäinen, O. K.; Hanhineva, K.; Delzenne, N.

10.1101/2024.02.27.582239 — neuroscience — Posted on 2024-07-08

4006 Next Generation Aging Clock: A Novel Approach to Decoding Human Aging Through Over 3000 Cellular Pathways

Xiong, J.

10.1101/2024.06.18.599632 — systems biology — Posted on 2024-07-08

4007 Decoding Missense Variants by Incorporating Phase Separation via Machine Learning

Feng, M.; Wei, X.; Zheng, X.; Liu, L.; Lin, L.; Xia, M.; He, G.; Shi, Y.; Lu, Q.

10.1101/2024.04.01.587546 — bioinformatics — Posted on 2024-07-08

4008 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity

Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.

10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-08

4009 A highly divergent mitochondrial genome in extant Cape buffalo from Addo Elephant National Park, South Africa

de Jager, D.; Moller, M.; Hoal, E. G.; van Helden, P.; Glanzmann, B.; Harper, C. K.; Bloomer, P.

10.1101/2023.01.14.524049 — genetics — Posted on 2024-07-08

4010 Trans-eQTL hotspots shape complex traits by modulating cellular states

Renganaath, K.; Albert, F. W.

10.1101/2023.11.14.567054 — genetics — Posted on 2024-07-08

4011 Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

Wang, P.-K.; Lin, K.-h.; Tang, T. K.

10.1101/2024.06.17.598507 — cell biology — Posted on 2024-07-08

4012 Hexokinase 2 expression in apical enterocytes correlates with inflammation severity in patients with inflammatory bowel disease

Weber-Stiehl, S.; Taubenheim, J.; Jaerke, L.; Roecken, C.; Schreiber, S.; Aden, K.; Kaleta, C.; Rosenstiel, P.; Sommer, F.

10.1101/2024.04.04.588060 — immunology — Posted on 2024-07-08

4013 Physical constraints on the positions and dimensions of the zebrafish swim bladder by surrounding bones

Satoh, K.; Maeno, A.; Adachi, U.; Ishizaka, M.; Yamada, K.; Koita, R.; Nakazawa, H.; Oikawa, S.; Fujii, R.; Furudate, H.; Kawamura, A.

10.1101/2024.07.04.602051 — developmental biology — Posted on 2024-07-08

4014 Tks5 interactome reveals ER-associated machinery translation in invadosomes.

NORMAND, L.; BONNARD, B.; Sala, M.; DI-TOMMASO, S.; DOURTHE, C.; RAYMOND, A.-A.; DUPUY, J.-W.; MERCIER, L.; GOETZ, J. G.; MOREAU, V.; HENRIET, E.; SALTEL, F.

10.1101/2024.07.02.601728 — cancer biology — Posted on 2024-07-08

4015 Transcriptomic Hallmarks of Mortality Reveal Universal and Specific Mechanisms of Aging, Chronic Disease, and Rejuvenation

Tyshkovskiy, A.; Kholdina, D.; Ying, K.; Davitadze, M.; Moliere, A.; Tongu, Y.; Kasahara, T.; Kats, L. M.; Vladimirova, A.; Moldakozhayev, A.; Liu, H.; Zhang, B.; Khasanova, U.; Moqri, M.; Van Raamsdonk, J. M.; Harrison, D. E.; Strong, R.; Abe, T.; Dmitriev, S. E.; Gladyshev, V. N.

10.1101/2024.07.04.601982 — systems biology — Posted on 2024-07-07

4016 Shikimate pathway-Dependent Catabolism:enabling near-to-maximum production yield of aromatics

Bruinsma, L.; Batianis, C.; Moreno Paz, S.; Kurnia, K.; Dirkmaat, J.; Muller, A.; Juncosa Nunez, J.; Weusthuis, R.; Martins dos Santos, V. A. P.

10.1101/2024.07.06.602327 — synthetic biology — Posted on 2024-07-07

4017 Multi-omic profiling of intraductal papillary neoplasms of the pancreas reveals distinct expression patterns and potential markers of progression

Wang, Y.; Lih, T.-S. M.; Lee, J. W.; Ohtsuka, T.; Hozaka, Y.; Mino-Kenudson, M.; Adsay, N. V.; Luchini, C.; Scarpa, A.; Maker, A. V.; Kim, G. E.; Paulino, J.; Chen, L.; Jiao, L.; Sun, Z.; Goodman, D.; Pfluger, M. J.; Roberts, N. J.; Matthaei, H.; Wood, L. D.; Furukawa, T.; Zhang, H.; Hruban, R. H.

10.1101/2024.07.07.602385 — cancer biology — Posted on 2024-07-07

4018 Library size can undermine accurate molecular and phenotypic subtyping in spatial transcriptomics data.

Fisher, N. C.; Malla, S. B.; Jamieson, N.; Dunne, P. D.

10.1101/2024.07.07.602370 — cancer biology — Posted on 2024-07-07

4019 Hedgehog-Hippo pathway interactions promote T cell exclusion from the tumor microenvironment in basal cell carcinoma

Aberger, F.; Stockmaier, G.; Varkhande, S.; Krenn, P. W.; Dang, H.-h.; Sharma, A.; Elmer, D. P.; Steiner, M.; Zaborsky, N.; Neureiter, D.; Greil, R.; Horejs-Hoeck, J.; Fortelny, N.; Gratz, I. K.

10.1101/2024.07.07.602398 — cancer biology — Posted on 2024-07-07

4020 TRPML1 gating modulation by allosteric mutations and lipids

Gan, N.; Han, Y.; Zeng, W.; Jiang, Y.

10.1101/2024.07.04.602033 — biophysics — Posted on 2024-07-07

4021 Development and Characterization of 50 nanometer diameter Genetically Encoded Multimeric Nanoparticles

Hernandez, C. M.; Duran Chaparro, D. C.; van Eeuwen, T.; Rout, M.; Holt, L. J.

10.1101/2024.07.05.602291 — biophysics — Posted on 2024-07-07

4022 Breaking free from references: a consensus-based approach for community profiling with long amplicon nanopore data

Stock, W.; Rousseau, C.; Dierickx, G.; D'hondt, S.; Martinez, L. A.; Dittami, S. M.; van der Loos, L.; De Clerck, O.

10.1101/2024.07.04.602031 — bioinformatics — Posted on 2024-07-07

4023 Benchmarking algorithms for spatially variable gene identification in spatial transcriptomics

Chen, X.; Ran, Q.; Tang, J.; Chen, Z.; Huang, S.; Shi, X.; Xi, R.

10.1101/2024.07.04.602147 — bioinformatics — Posted on 2024-07-07

4024 GeneSurfer Enables Transcriptome-wide Exploration and Functional Annotation of Gene Co-expression Modules in 3D Spatial Transcriptomics Data

Li, C.; Thijssen, J.; Kroes, T.; van der Burg, X.; van der Weerd, L.; Höllt, T.; Lelieveldt, B.

10.1101/2024.07.05.602230 — bioinformatics — Posted on 2024-07-07

4025 Ultra-resolution Deconvolution of Spatial Transcriptomics Unveils Spatiotemporal Cellular Dynamics in Complex Microenvironments

Xu, Y.; Huang, Z.; Zhang, Y.; Wang, Z.; Guo, P.; Zhang, F.; Gong, W.; Liang, G.; Mei, B.; Dong, L.; Chang, R.; Gong, M.; Xia, Y.; Ni, H.; Yang, J.; Gao, Y.; Liu, Z.; Shen, L.; Li, J.; Xu, M. M.; Han, D.

10.1101/2024.07.05.602200 — bioinformatics — Posted on 2024-07-07

4026 SOFisher: Reinforcement Learning-Guided Experiment Designs for Spatial Omics

Li, Z.; Wu, W.; Cui, Y.; Jian, S.; Yuan, Z.

10.1101/2024.07.05.602236 — bioinformatics — Posted on 2024-07-07

4027 MIST: an interpretable and flexible deep learning framework for single-T cell transcriptome and receptor analysis

Lai, W.; Li, Y.; Luo, O. J.

10.1101/2024.07.05.602192 — bioinformatics — Posted on 2024-07-07

4028 'Target-and-release' nanoparticles for effective immunotherapy of metastatic ovarian cancer

Pires, I. S.; Covarrubias, G.; Gomerdinger, V. F.; Backlund, C. M.; Shanker, A.; Gordon, E.; Wu, S.; Pickering, A. J.; Melo, M. B.; Suh, H.; Irvine, D. J.; Hammond, P. T.

10.1101/2024.07.05.602135 — bioengineering — Posted on 2024-07-07

4029 In vivo CRISPR base editing for treatment of Huntington's disease

Shirguppe, S.; Gapinske, M.; Swami, D.; Gosstola, N.; Acharya, P.; Miskalis, A.; Joulani, D.; Szkwarek, M. G.; Bhattacharjee, A.; Elias, G.; Stilger, M.; Winter, J.; Woods, W. S.; Anand, D.; Lim, C. K. W.; Gaj, T.; Perez-Pinera, P.

10.1101/2024.07.05.602282 — bioengineering — Posted on 2024-07-07

4030 Quantification and site-specific analysis of co-occupied N- and O-glycopeptides

Chongsaritsinsuk, J.; Rangel-Angarita, V.; Mahoney, K. E.; Lucas, T. M.; Enny, O. M.; Katemauswa, M.; Malaker, S. A.

10.1101/2024.07.06.602348 — biochemistry — Posted on 2024-07-07

4031 Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53

Wendrich, K.; Gallant, K.; Recknagel, S.; Petroulia, S.; Führer, S.; Bezstarosti, K.; O'Dea, R.; Demmers, J.; Gersch, M.

10.1101/2024.07.07.602376 — biochemistry — Posted on 2024-07-07

4032 Hierarchical structural organization in bioinspired peptide coacervate microdroplets

Lim, J.; Gudlur, S.; Buchanan, C.; Perrin, Q.; Boyd, H.; Moulin, M.; Iwase, H.; Porcar, L.; Cardenas, M.; Miserez, A.; Pervushin, K.

10.1101/2024.07.06.602323 — biochemistry — Posted on 2024-07-07

4033 An adaptor for feedback regulation of heme biosynthesis by the mitochondrial protease CLPXP

Cottle, T.; Joh, L.; Posner, C.; DeCosta, A.; Kardon, J. R.

10.1101/2024.07.05.602318 — biochemistry — Posted on 2024-07-07

4034 Near-complete telomere-to-telomere de novo genome assemblies of Egyptian clover (Trifolium alexandrinum)

Sato, M. P.; Arafa, R. A.; Rakha, M.; Emeran, A. A.; Isobe, S.; Shirasawa, K.

10.1101/2024.07.04.602140 — genomics — Posted on 2024-07-07

4035 Insights into non-crossover recombination from long-read sperm sequencing

Schweiger, R.; Lee, S.; Zhou, C.; Yang, T.-P.; Smith, K.; Li, S.; Sanghvi, R.; Neville, M.; Mitchell, E.; Nessa, A.; Wadge, S.; Small, K. S.; Campbell, P. J.; Sudmant, P. H.; Rahbari, R.; Durbin, R.

10.1101/2024.07.05.602249 — genetics — Posted on 2024-07-07

4036 Frequent transitions in self-assembly across the evolution of a central metabolic enzyme

Sendker, F. L.; Schlotthauer, T.; Mais, C.-N.; Lo, Y. K.; Girbig, M.; Bohn, S.; Heimerl, T.; Schindler, D.; Weinstein, A.; Metzger, B. P.; Thornton, J. W.; Pillai, A.; Bange, G.; Schuller, J.; Hochberg, G.

10.1101/2024.07.05.602260 — evolutionary biology — Posted on 2024-07-07

4037 Plastid translocon recycling in dinoflagellates demonstrates the portability of complex plastids between hosts

Lewis, W. H.; Paris, G.; Beedessee, G.; Koreny, L.; Flores, V.; Dendooven, T.; Gallet, B.; Yee, D. P.; Lam, S.; Decelle, J.; Luisi, B.; Waller, R. F.

10.1101/2024.07.06.602338 — evolutionary biology — Posted on 2024-07-07

4038 A probabilistic view of forbidden links: their prevalence and their consequences for the robustness of mutualistic networks

Duchenne, F.; Barreto, E.; Guevara, E. A.; Beck, H.; Bello, C.; Bobato, R.; Bolla, D.; Brenes, E.; Büttner, N.; Caron, A. P.; Elizondo, N.; Restrepo-Gonzalez, A.; Castro, J. A.; Kaehler, M.; Machado-de-Souza, T.; Machnicki-Reis, M.; Marcayata-Fajardo, A. S.; de Menezes, C. G.; Nieto, A.; de Oliveira, R.; de Oliveira, R. A. C.; Richter, F.; Rojas, B. G.; Romanowski, L. L.; de Souza, W. L.; Veluza, D. S.; Weinstein, B.; Wüest, R.; Zanata, T. B.; Zuniga, K.; Maglianesi, M. A.; Santander, T.; Varassin, I. G.; Graham, C. H.

10.1101/2024.07.04.602032 — ecology — Posted on 2024-07-07

4039 A conserved RNA switch for acetylcholine receptor clustering at neuromuscular junctions in chordates

Hossain, M. F.; Popsuj, S.; Vitrinel, B.; Kaplan, N. A.; Stolfi, A.; Christiaen, L.; Ruggiu, M.

10.1101/2024.07.05.602308 — developmental biology — Posted on 2024-07-07

4040 Spatial organization of PI3K-PI(3,4,5)P3-AKT signaling by focal adhesions

Wang, J.; An, Z.; Wu, Z.; Zhou, W.; Sun, P.; Wu, P.; Xue, R.; Dang, S.; Bai, X.; Wang, W.; Chen, R.; Du, Y.; Huang, P.; Lam, S. M.; Ai, Y.; Liu, S.; Shui, G.; Zhang, Z.; Liu, Z.; Huang, J.; Fang, X.; He, K.

10.1101/2024.07.05.602013 — cell biology — Posted on 2024-07-07

4041 INF2-mediated actin polymerization at ER-organelle contacts regulates organelle size and movement

Schiavon, C. R.; Wang, Y.; Feng, J. W.; Garrett, S.; Dayn, Y.; Sung, T.-C.; Wang, C.; Youle, R. J.; Quintero-Carmona, O. A.; Shadel, G. S.; Manor, U.

10.1101/2024.07.06.602365 — cell biology — Posted on 2024-07-07

4042 Einstein from Noise: Statistical Analysis

Balanov, A.; Huleihel, W.; Bendory, T.

10.1101/2024.07.06.602366 — molecular biology — Posted on 2024-07-07

4043 Unveiling reversibility and plasticity in cardiac hypertrophy: insights from a transverse aortic constriction-release model

Shiraishi, M.

10.1101/2024.07.07.602358 — molecular biology — Posted on 2024-07-07

4044 Treatment with 2-phospho-L-ascorbic acid mitigates biochemical phenotypes of heme oxygenase 1 deficiency

Berendes, L.-S.; Schulze Westhoff, P.; Tobinski, A.-M.; Wingert, V.; Biskup, S.; Seelhoefer, A.; Van Marck, V.; Heitplatz, B.; Wittkowski, H.; Das, A. M.; Hannibal, L.; Nowak, W. N.; Jozkowicz, A.; Klotz, L.; Varga, G.; Marquardt, T.; Park, J. H.

10.1101/2024.07.05.602073 — molecular biology — Posted on 2024-07-07

4045 Novel single-cell preservation and RNA sequencing technology unlocks field studies for Plasmodium natural infections

Sauve, E. L.; Monsieurs, P.; Guetens, P.; Moraes Barros, R. R.; Rosanas-Urgell, A.

10.1101/2024.07.05.602255 — microbiology — Posted on 2024-07-07

4046 RNA genome expansion up to 64 kb in nidoviruses is host constrained and associated with new modes of replicase expression

Neuman, B. W.; Smart, A.; Vaas, J.; Bartenschlager, R.; Seitz, S.; Gorbalenya, A. E.; Caliskan, N. E.; Lauber, C.

10.1101/2024.07.07.602380 — microbiology — Posted on 2024-07-07

4047 Jellyfish blooms - an overlooked hotspot and potential vector for the transmission of antimicrobial resistance in marine environments

Elena, A. X.; Orel, N.; Fang, P.; Herndl, G. J.; Berendonk, T. U.; Tinta, T.; Kluemper, U.

10.1101/2024.07.07.602378 — microbiology — Posted on 2024-07-07

4048 Co-option of mitochondrial nucleic acid sensing pathways by HSV-1 UL12.5 for reactivation from latent Infection

Cuddy, S.; Krakowiak, P. A.; Flores, M. E.; Whitford, A. L.; Dochnal, S. A.; Babnis, A.; Miyake, T.; Tigano, M.; Engel, D. A.; Cliffe, A. R.

10.1101/2024.07.06.601241 — microbiology — Posted on 2024-07-07

4049 Single-cell omics for complex microbial communities

Lan, X.; Liang, Q.; Wu, J.; He, J.; Zhang, X.; Li, F.; Zhao, G.-P.; Guo, R.; Jia, H.

10.1101/2024.07.07.602369 — microbiology — Posted on 2024-07-07

4050 Integrative genomic reconstruction of carbohydrate utilization networks in bifidobacteria: global trends, local variability, and dietary adaptation

Arzamasov, A. A.; Rodionov, D. A.; Hibberd, M. C.; Guruge, J. L.; Kazanov, M. D.; Leyn, S. A.; Kent, J. E. D.; Sejane, K.; Bode, L.; Barratt, M. J.; Gordon, J.; Osterman, A.

10.1101/2024.07.06.602360 — microbiology — Posted on 2024-07-07

4051 The regulatory functions of ESX-1 substrates, EspE and EspF, are separable from secretion.

Prest, R. J.; Korotkov, K. V.; Champion, P. A.

10.1101/2024.07.05.602283 — microbiology — Posted on 2024-07-07

4052 Identification of P-type ATPase as a bacterial transporter for host-derived small RNA

Dong, P.-T.; Yang, M.; Cen, L.; Zhou, P.; Xu, D.; Xiong, P.; Wu, C.; Li, J.; He, X.

10.1101/2024.07.05.602285 — microbiology — Posted on 2024-07-07

4053 Non-canonical activation of the ESCRT machinery is required for division of Leishmania donovani parasitophorous vacuoles and persistence

Kima, P. E.; Rosero, J.

10.1101/2024.07.06.602309 — microbiology — Posted on 2024-07-07

4054 Interspecies interaction reshapes the fitness landscape of evolved genotypes

Sun, X.; Xu, Z.; Hu, G.; Xie, J.; Li, Y.; Tao, L.; Zhang, N.; Xun, W.; Miao, Y.; Zhang, R.; Shen, Q.; Kovacs, A. T.

10.1101/2024.07.06.602328 — microbiology — Posted on 2024-07-07

4055 Comparing Raman and NanoSIMS for heavy water labeling of single cells

Schaible, G.; Cliff, J.; Crandall, J.; Bougoure, J.; Atwood, J.; Hatzenpichler, R.

10.1101/2024.07.05.602271 — microbiology — Posted on 2024-07-07

4056 Multiple stressor effects on organic carbon degradation and microbial community composition in urban river sediments in a mesocosm experiment

Baikova, D.; Hadziomerovic, U.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V.; Meckenstock, R. U.

10.1101/2024.07.05.602289 — microbiology — Posted on 2024-07-07

4057 Acidotolerant soil nitrite oxidiser 'Candidatus Nitrobacter laanbroekii' NHB1 alleviates constraints on growth of acidophilic soil ammonia oxidisers

Hink, L.; Bachtsevani, E.; Meng, Y.; Sedlacek, C. J.; Lee, S.; Daims, H.; Wagner, M.; Gubry-Rangin, C.; de Boer, W.; Hazard, C.; Prosser, J. I.; Nicol, G. W.

10.1101/2024.07.06.601931 — microbiology — Posted on 2024-07-07

4058 Diel changes in the expression of a marker gene and candidate genes for intracellular amorphous CaCO3 biomineralization in Microcystis

Bruley, A.; Gaëtan, J.; Gugger, M.; Pancrace, C.; Millet, M.; Gaschignard, G.; Dezi, M.; Humbert, J.-F.; Leloup, J.; Skouri-Panet, F.; Callebaut, I.; Benzerara, K.; Duprat, E.

10.1101/2024.07.07.602159 — microbiology — Posted on 2024-07-07

4059 A Universal, Single-Component Multilayered Self-Assembling Protein Nanoparticle Vaccine Based on Extracellular Domains of Matrix Protein 2 Against Both Influenza A and B

Zhang, Y.-N.; Gomes, K. B.; Lee, Y.-Z.; Ward, G.; Xie, B.; Auclair, S.; He, L.; Zhu, J.

10.1101/2024.07.05.602266 — microbiology — Posted on 2024-07-07

4060 Synergically enhanced anti-tumor immunity of in vivo CAR by circRNA vaccine boosting

Wang, Y.; Lin, L.; Wang, X.; Li, J.; Yin, J.; Gao, F.; Liao, X.; Zhang, C.; Yin, Q.; Zhao, C.; Lin, J.; Xu, Y.; Qiu, M.; Luo, D.; Qu, L.

10.1101/2024.07.05.600312 — immunology — Posted on 2024-07-07

4061 Rebalancing Viral and Immune Damage versus Tissue Repair Prevents Death from Lethal Influenza Infection

Ichise, H.; Speranza, E.; La Russa, F.; Veres, T. Z.; Chu, C. J.; Gola, A.; Germain, R. N.

10.1101/2024.07.04.601620 — immunology — Posted on 2024-07-07

4062 Organizational principles of the primate cerebral cortex at the single-cell level

Chen, R.; Nie, P.; Ma, L.; Wang, G.-Z.

10.1101/2024.07.05.602270 — neuroscience — Posted on 2024-07-07

4063 Inhibitory neurons defined by a synaptogenic molecule impair memory discrimination

Tunon-Ortiz, A. B. N.; Trankner, D.; Raines, O. K.; Mahnke, A.; Brockway, S.; Grega, M.; Zelikowsky, M.; Williams, M. E.

10.1101/2024.07.05.602304 — neuroscience — Posted on 2024-07-07

4064 Diffusion Basis Spectrum Imaging of White Matter in Schizophrenia and Bipolar Disorder

Mamah, D.; Patel, A.; Chen, S.; Wang, Y.; Wang, Q.

10.1101/2024.07.07.602402 — neuroscience — Posted on 2024-07-07

4065 Valence and Salience Encoding in the Central Amygdala

Kong, M.-S.; Ancell, E.; Witten, D. M.; Zweifel, L. S.

10.1101/2024.07.05.602310 — neuroscience — Posted on 2024-07-07

4066 The rhythmic transcriptional landscape in Caenorhabditis elegans: daily, circadian and novel 16-hour cycling gene expression revealed by RNA-sequencing

Munns, J.; Newling, K.; James, S. R.; Gilbert, L.; Davis, S. J.; Chawla, S.

10.1101/2024.07.06.602329 — physiology — Posted on 2024-07-07

4067 Membrane permeability selection drove the stereochemistry of life

Goode, O.; Lapinska, U.; Glover, G.; Milner, D. S.; Santoro, A. E.; Pagliara, S.; Richards, T.

10.1101/2024.04.23.590732 — evolutionary biology — Posted on 2024-07-08

4068 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria

Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.

10.1101/2024.02.24.581832 — microbiology — Posted on 2024-07-08

4069 E. coli division machinery drives cocci development inside host cells

Pokhrel, A.; Costas, A.; Pittorino, M.; Duggin, I. G.; Söderström, B.

10.1101/2024.04.08.588611 — microbiology — Posted on 2024-07-08

4070 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction

Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.

10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-07-08

4071 Determination of the absolute concentration of Rayleigh particles via scattering microscopy

Lee, I.-B.; Moon, H.-M.; Park, J.-S.; Lee, S.-H.; Lee, J.; Park, S. H.; Lee, S.; Hong, S.-C.; Cho, M.

10.1101/2024.06.08.598040 — biophysics — Posted on 2024-07-08

4072 AutoPeptideML: A study on how to build more trustworthy peptide bioactivity predictors

Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.

10.1101/2023.11.13.566825 — bioinformatics — Posted on 2024-07-08

4073 Network for Knowledge Organization (NEKO): an AI knowledge mining workflow for synthetic biology research

Xiao, Z.; Pakrasi, H.; Chen, Y.; Tang, Y.

10.1101/2024.06.27.601082 — bioengineering — Posted on 2024-07-08

4074 Intracellular pH differentially regulates transcription of metabolic and signaling pathways in normal epithelial cells

Moreno, R. R.; Czowski, B.; Harris, L.; Kuehn, J. F.; White, K. A.

10.1101/2022.07.12.499804 — biochemistry — Posted on 2024-07-07

4075 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum

Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.

10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-07

4076 Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses

Ma, C.-B.; Liu, C.; Park, Y.-J.; Tang, J.; Chen, J.; Xiong, Q.; Lee, J.; Stewart, C.; Asarnow, D.; Brown, J.; Tortorici, M. A.; Yang, X.; Sun, Y.-H.; Chen, Y.-M.; Yu, X.; Si, J.-Y.; Liu, P.; Tong, F.; Huang, M.-L.; Li, J.; Shi, Z.-L.; Deng, Z.; Veesler, D.; Yan, H.

10.1101/2023.10.02.560486 — microbiology — Posted on 2024-07-08

4077 Examining heterogeneity in dementia using data-driven unsupervised clustering of cognitive profiles

Kumar, S.; Oh, I.; Schindler, S. E.; Ghoshal, N.; Abrams, Z.; Payne, P. R.

10.1101/2024.06.13.598874 — neuroscience — Posted on 2024-07-07

4078 Single-molecule analysis reveals the phosphorylation of FLS2 governs its spatiotemporal dynamics and immunity

Cui, Y.; Qian, H.; Yin, J.; Xu, C.; Luo, P.; Zhang, X.; Yu, M.; Su, B.; Li, X.; Lin, J.

10.1101/2023.08.22.553824 — plant biology — Posted on 2024-07-07

4079 The regulatory functions of ESX-1 substrates, EspE and EspF, are separable from secretion.

Prest, R. J.; Korotkov, K. V.; Champion, P. A.

10.1101/2024.07.05.602283 — microbiology — Posted on 2024-07-07

4080 Shikimate pathway-Dependent Catabolism:enabling near-to-maximum production yield of aromatics

Bruinsma, L.; Batianis, C.; Moreno Paz, S.; Kurnia, K.; Dirkmaat, J.; Muller, A.; Juncosa Nunez, J.; Weusthuis, R.; Martins dos Santos, V. A. P.

10.1101/2024.07.06.602327 — synthetic biology — Posted on 2024-07-07

4081 Non-canonical activation of the ESCRT machinery is required for division of Leishmania donovani parasitophorous vacuoles and persistence

Kima, P. E.; Rosero, J.

10.1101/2024.07.06.602309 — microbiology — Posted on 2024-07-07

4082 Multiple stressor effects on organic carbon degradation and microbial community composition in urban river sediments in a mesocosm experiment

Baikova, D.; Hadziomerovic, U.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V.; Meckenstock, R. U.

10.1101/2024.07.05.602289 — microbiology — Posted on 2024-07-07

4083 Interspecies interaction reshapes the fitness landscape of evolved genotypes

Sun, X.; Xu, Z.; Hu, G.; Xie, J.; Li, Y.; Tao, L.; Zhang, N.; Xun, W.; Miao, Y.; Zhang, R.; Shen, Q.; Kovacs, A. T.

10.1101/2024.07.06.602328 — microbiology — Posted on 2024-07-07

4084 Identification of P-type ATPase as a bacterial transporter for host-derived small RNA

Dong, P.-T.; Yang, M.; Cen, L.; Zhou, P.; Xu, D.; Xiong, P.; Wu, C.; Li, J.; He, X.

10.1101/2024.07.05.602285 — microbiology — Posted on 2024-07-07

4085 Time is of the essence: A general framework for uncovering temporal structures of communities

Yin, H.; Rudolf, V.

10.1101/2023.06.30.546877 — ecology — Posted on 2024-07-07

4086 Targeting mitochondrial metabolism with CPI-613 in chemoresistant ovarian tumors

Udumula, M. P.; Rashid, F.; Singh, H.; Pardee, T.; Luther, S.; Bhardwaj, T.; Anjaly, K.; Piloni, S.; Hijaz, M.; Gogoi, R.; Philip, P. A.; Munkarah, A.; Giri, s.; Rattan, R.

10.1101/2024.05.16.594585 — cancer biology — Posted on 2024-07-07

4087 The mod-minimizer: a simple and efficient sampling algorithm for long k-mers

Groot Koerkamp, R.; Pibiri, G. E.

10.1101/2024.05.25.595898 — bioinformatics — Posted on 2024-07-07

4088 A kinetochore-centrosome feedback loop linking CENP-E and Aurora kinases controls chromosome biorientation and congression

Vukusic, K.; Tolic, I. M.

10.1101/2023.10.19.563150 — cell biology — Posted on 2024-07-07

4089 CRF release from a unique subpopulation of accumbal neurons constrains action-outcome acquisition in reward learning

Eckenwiler, E. A.; Ingebretson, A. E.; Stolley, J. J.; Fusaro, M. A.; Romportl, A. M.; Ross, J. M.; Petersen, C. L.; Kale, E. M.; Clark, M. S.; Schattauer, S. S.; Zweifel, L. S.; Lemos, J. C.

10.1101/2023.11.16.567495 — neuroscience — Posted on 2024-07-07

4090 Zero-shot animal behavior classification with vision-language foundation models

Dussert, G.; Miele, V.; Van Reeth, C.; Delestrade, A.; Dray, S.; Chamaille-Jammes, S.

10.1101/2024.04.05.588078 — ecology — Posted on 2024-07-07

4091 Discovery of a novel albendazole-ivermectin refractory Trichuris species, T. hominis, in Cote d'Ivoire patients through fecal DNA metabarcoding

Venkatesan, A.; Chen, R.; Bär, M. A.; Schneeberger, P.; Reimer, B.; Hürlimann, E.; Coulibaly, J. T.; Ali, S. M.; Sayasone, S.; Soghigian, J.; Keiser, J.; Gilleard, J. S.

10.1101/2024.07.04.602123 — genomics — Posted on 2024-07-07

4092 Transcriptional noise sets fundamental limits to spatially resolved cell-state decoding of the circadian clock.

Nikhat, A.; Mandal, T.; Veerasubramanian, N.; Chakrabarti, S.

10.1101/2024.06.30.601408 — cell biology — Posted on 2024-07-07

4093 Heightened lateral habenula activity during stress produces brainwide and behavioral substrates of susceptibility

Zhukovskaya, A.; Christopher, Z.; Willmore, L.; Pan Vazquez, A.; Janarthanan, S.; Falkner, A.; Witten, I.

10.1101/2023.11.06.565681 — neuroscience — Posted on 2024-07-07

4094 Concurrent optogenetic motor mapping of multiple limbs in awake mice reveals cortical organization of coordinated movements

Khanal, N.; Padawer-Curry, J. A.; Voss, T.; Schulte, K.; Bice, A. R.; Bauer, A. Q.

10.1101/2024.07.05.602302 — neuroscience — Posted on 2024-07-06

4095 Developmental encoding of ultrasound vocalizations in the mouse auditory cortex

Zucca, S.; La Rosa, C.; Fellin, T.; Peretto, P.; Bovetti, S.

10.1101/2024.07.05.601869 — neuroscience — Posted on 2024-07-06

4096 Altered cortico-cerebellar connectivity in cerebellar degeneration patients improves with motor training

Nettekoven, C.; Draganova, R.; Steiner, K. M.; Goericke, S. L.; Deistung, A.; Konczak, J.; Timmann, D.

10.1101/2024.07.05.602300 — neuroscience — Posted on 2024-07-06

4097 Microbiota from young mice counteracts susceptibility to age-related gout through modulating butyric acid levels in aged mice

Song, N.; Gao, H.; Li, J.; Liu, Y.; Wang, M.; Ma, Z.; Zhang, N.; Zhang, W.

10.1101/2024.04.22.590443 — microbiology — Posted on 2024-07-07

4098 Dual-mode action of scalable, high-quality engineered stem cell-derived SIRPα-extracellular vesicles for treating acute liver failure

Kim, S.; Kim, Y. K.; Kim, S.; Choi, Y.-S.; Lee, I.; Joo, H.; Kim, J.; Kwon, M.; Park, S.; Jo, M. K.; Choi, Y.; D'Souza, T.; Jung, J. W.; Zakhem, E.; Lenzini, S.; Woo, J.; Choi, H.; Park, J.; Park, S.-Y.; Kim, G. B.; Nam, G.-H.; Kim, I.-S.

10.1101/2024.05.24.592430 — bioengineering — Posted on 2024-07-07

4099 A metabolic modeling-based framework for predicting trophic dependencies in native rhizobiomes of crop plants

Ginatt, A. A.; Berihu, M.; Castel, E.; Medina, S.; Carmi, G.; Doron-Faigenboim, A.; Sharon, I.; Tal, O.; Droby, S.; Somera, T.; Mazzola, M.; Eizenberg, H.; Freilich, S.

10.1101/2023.12.11.571117 — microbiology — Posted on 2024-07-07

4100 Prdm1 Positively Regulates Liver Group 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity

He, J.; Gao, L.; Wang, P.; Chan, W. K.; Zheng, Y.; Zhang, Y.; Sun, J.; Li, X.; Wang, J.; Li, X.; Chen, H.; Yang, Z.; Wang, Y.

10.1101/2023.10.20.563222 — immunology — Posted on 2024-07-07

4101 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation

Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.

10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-07-07

4102 Neural processing of rhythmic speech by children with developmental language disorder (DLD): An EEG study

Keshavarzi, M.; Richards, S.; Feltham, G.; Parvez, L.; Goswami, U.

10.1101/2024.03.29.587020 — neuroscience — Posted on 2024-07-06

4103 Cortical circuits for cross-modal generalization

Guyoton, M.; Matteucci, G.; Foucher, C. G.; Getz, M. P.; Gjorgjieva, J.; El-Boustani, S.

10.1101/2023.10.13.562215 — neuroscience — Posted on 2024-07-06

4104 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study

Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.

10.1101/2023.09.29.559614 — plant biology — Posted on 2024-07-06

4105 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity

10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-06

4106 Draft genomes of a male and female Australian jacky dragon (Amphibolurus muricatus)

Tian, R.; Dong, H.; Zhang, F.; Yu, H.; Pei, E.; Shi, C.; Fan, G.; Whiteley, S. L.; Holleley, C. E.; Seim, I.; Georges, A.

10.1101/2021.10.11.463868 — genomics — Posted on 2024-07-06

4107 Mitochondria-derived Vesicles mediate Mito-nuclear Trafficking of Cargo

Rajeev, T.; Shil, D.; Bhattacharjee, S.; Ramesh, L.; Samuel, V.; Nair, N. Y.; Marib, A.; Jayakumar, M.; Gayathri, S.; Surendran, A.; Johnson, J. B.; Sundararaman, A.

10.1101/2024.05.04.592299 — cell biology — Posted on 2024-07-06

4108 Mitochondria- and ER-associated actin are required for mitochondrial fusion

Gatti, P.; Schiavon, C. R.; Manor, U.; Germain, M.; Cicero, J.

10.1101/2023.06.13.544768 — cell biology — Posted on 2024-07-06

4109 Cellular and molecular events organizing the assembly of tertiary lymphoid structures in glioblastoma

Vaccaro, A.; Yang, F.; van de Walle, T.; Franke, S.; Lugano, R.; Denes, A.; Magoulopoulou, A.; Cid-Farina, I.; Smits, A.; Uhrbom, L.; Libard, S.; Latini, F.; Essand, M.; Nilsson, M.; He, L.; Olsson Bontell, T.; Jakola, A. S.; Ramachandran, M.; Dimberg, A.

10.1101/2024.07.04.601824 — cancer biology — Posted on 2024-07-06

4110 Worldwide Soundscapes: a synthesis of passive acoustic monitoring across realms

Darras, K. F.; Rountree, R.; Van Wilgenburg, S.; Cord, A. F.; Pitz, F.; Chen, Y.; Dong, L.; Gasc, A.; Lin, T.-H.; Diaz, P. M.; Wu, S.-H.; Salton, M.; Marley, S.; Schille, L.; Wensveen, P. J.; Desjonqueres, C.; Acevedo-Charry, O.; Adam, M.; Aguzzi, J.; Andre, M.; Antonelli, A.; Aparecido Do Nascimento, L.; Appel, G.; Astaras, C.; Atemasov, A.; Barbaro, L.; Basan, F.; Batist, C.; Baucells, A. L.; Baumgarten, J. E.; Bayle Sempere, J. T.; Bellisario, K.; Ben David, A.; Berger-Tal, O.; Betts, M. G.; Bhalla, I.; Bicudo, T.; Bolgan, M.; Bombaci, S.; Boullhesen, M.; Bradfer-Lawrence, T.; Briers, R. A.

10.1101/2024.04.10.588860 — ecology — Posted on 2024-07-06

4111 Seq2scFv: a toolkit for the comprehensive analysis of display libraries from long-read sequencing platforms

Bachmann Salvy, M.; Santuari, L.; Schmid-Siegert, E.; Lykoskoufis, N. M. R.; Xenarios, I.; Arpat, B.

10.1101/2024.07.04.602016 — immunology — Posted on 2024-07-06

4112 Asymmetric learning and adaptability to changes in relational structure during transitive inference

Graham, T. A.; Spitzer, B.

10.1101/2024.07.03.601844 — neuroscience — Posted on 2024-07-06

4113 PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles

Li, L.; Li, Y.; Huang, C.; Hou, W.; Lv, Z.; Zhang, L.; Qu, Y.; Sun, Y.; Huang, K.; Han, X.; He, Z.; Tai, F.-D.

10.1101/2024.03.06.583718 — neuroscience — Posted on 2024-07-06

4114 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance

Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.

10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-06

4115 TRAFICA: An Open Chromatin Language Model to ImproveTranscription Factor Binding Affinity Prediction

Xu, Y.; Wang, C.; Xu, K.; Ding, Y.; Lyu, A.; Zhang, L.

10.1101/2023.11.02.565416 — bioinformatics — Posted on 2024-07-06

4116 Times birds need to evolve mating cues under allopatry and parapatry

Sibly, R. M.; Curnow, R. N.

10.1101/2024.03.01.582980 — evolutionary biology — Posted on 2024-07-06

4117 Coherent Raman microscopy detects nucleolar defects through amide I peak shifts originating from β-sheets: an application to visualizing ongoing cellular senescence

Ishibashi, S.; Inoko, A.; Oka, Y.; Leproux, P.; Kano, H.

10.1101/2024.07.01.600896 — cell biology — Posted on 2024-07-06

4118 Localised Astrocyte Ca2+ Activity Regulates Neurovascular Coupling Responses to Active Sensing.

Stelzner, J. A.; Krogsgaard, A.; Kulkoviene, G.; Sperling, L.; Lind, B. L.

10.1101/2024.04.16.589720 — neuroscience — Posted on 2024-07-06

4119 Co-Transplantation-Based Human-Mouse Chimeric Brain Models to Study Human Glial-Glial and Glial-Neuronal Interactions

Jin, M.; Ma, Z.; Zhang, H.; Papetti, A. V.; Dang, R.; Stillitano, A. C.; Goldman, S. A.; Jiang, P.

10.1101/2024.07.03.601990 — neuroscience — Posted on 2024-07-06

4120 Atypical chemokine receptor 3 regulates synaptic removal in disease astrocytes

Giusti, V.; Park, J.; Giusto, E.; Masatti, L.; Ramos-Gonzales, P.; Iovino, L.; Sandre, M.; Emmi, A.; Kaur, G.; Coletto, E.; Calura, E.; Petrelli, F.; Porzionato, A.; De Caro, R.; Cavaliere, F.; Chung, W.-S.; Civiero, L.

10.1101/2024.07.03.601867 — neuroscience — Posted on 2024-07-06

4121 The flow of reward information through neuronal ensembles in the accumbens

Arroyo, B.; Hernandez-Lemus, E.; Gutierrez, R.

10.1101/2024.02.15.580379 — neuroscience — Posted on 2024-07-06

4122 Distinct inhibitory neurons differently shape neuronal codes for sound intensity in the auditory cortex

Tobin, M.; Sheth, J. N.; Wood, K. C.; Michel, E. K.; Geffen, M. N.

10.1101/2023.02.01.526470 — neuroscience — Posted on 2024-07-06

4123 Comparing arm to whole-body motor control disambiguates age-related deterioration from compensation

Mathieu, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.

10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-07-06

4124 Bait, not reward: CO2-enriched Nepenthes pitchers secrete toxic nectar

Lathika, C. C.; Sujatha, G. B.; Thomas, G.; Johnson, A. J.; Viswanathan, G.; Varghese, T. S.; Mohamed, S.; Shereefa, L. A.; Baby, S.

10.1101/2023.11.25.568661 — plant biology — Posted on 2024-07-06

4125 R2Dtool: Integration and visualization of isoform-resolved RNA features

Sethi, A. J.; Acera Mateos, P.; Hayashi, R.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.09.23.509222 — bioinformatics — Posted on 2024-07-06

4126 Binocular Listing's Law For Human Eyes' Misaligned Optical Components

Turski, J.

10.1101/2024.06.24.600541 — neuroscience — Posted on 2024-07-06

4127 Recombination landscape and karyotypic variations revealed by linkage mapping in the grapevine downy mildew pathogen Plasmopara viticola

Dvorak, E.; Mazet, I. D.; Couture, C.; Delmotte, F.; Foulongne-Oriol, M.

10.1101/2024.07.03.601951 — genetics — Posted on 2024-07-06

4128 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts

10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-06

4129 Visual information is broadcast among cortical areas in discrete channels

Yu, Y.; Stirman, J. N.; Dorsett, C. R.; Smith, S. L.

10.1101/469114 — neuroscience — Posted on 2024-07-06

4130 qMAP Enabled Microanatomical Mapping of Human Skin Aging

Han, K. S.; Sander, I. B.; Kumer, J.; Resnick, E. P.; Booth, C.; Im, Y.; Cheng, G.; Starich, B.; Kiemen, A. L.; Phillip, J. M.; Reddy, S.; Joshu, C.; Sunshine, J.; Walston, J.; Wirtz, D.; Wu, P.-H.

10.1101/2024.04.03.588011 — pathology — Posted on 2024-07-06

4131 A novel HER2 protein identification methodology in breast cancer cells using Raman spectroscopy and Raman imaging: an analytical validation study

Abramczyk, H.; Surmacki, J. M.; Kopec, M.

10.1101/2024.07.04.602049 — cancer biology — Posted on 2024-07-06

4132 Estimating gene conversion tract length and rate from PacBio HiFi data

Charmouh, A. P.; Porsborg, P. S.; Bataillon, T.; Hobolth, A.; Hansen, L. T.; Besenbacher, S.; Winge, S. B.; Almstrup, K.; Schierup, M. H.

10.1101/2024.07.05.601865 — genomics — Posted on 2024-07-06

4133 Comprehensive Molecular Epidemiology of Influenza Viruses in Brazil: Insights from a Nationwide Analysis

Brcko, I. C.; de Souza, V. C.; Ribeiro, G.; Lima, A. R. J.; Martins, A. J.; Barros, C. R. d. S.; Carvalho, E.; Pereira, J. S.; de Lima, L. P. O.; Viala, V. L.; Kashima, S.; de La-Roque, D. G. L.; Santos, E. V.; Rodrigues, E. S.; Nunes, J. A.; Torres, L. S.; Caldeira, L. A. V.; Palmieri, M.; Medina, C. G.; Augusto de Arruda, R.; Lopes, R. B.; Reple Sobrinho, G.; Jorge, D. M. d. M.; Arruda, E.; Mendes, E. C. B. d. S.; Santos, H. d. O.; de Mello, A. L. e. S.; Pereira, F. M.; Gomez, M. K. A.; Nardy, V. B.; Henrique, B. V. M.; Vieira, L. L.; Roll, M. M.; de Oliveira, E. C.; Almeida, J. D. P. C.; da

10.1101/2024.07.04.602044 — evolutionary biology — Posted on 2024-07-06

4134 PD-1 blockade enhances HIV-1 vaccine-induced CD8+ T-cell responses in PWH early ART-treated

Marin, M.; Ruiz, A.; Jimenez-Moyano, E.; Ouchi, D.; Blanch-Lombarte, O.; Penya, R.; Gorman, D.; Barnard, R.; Hanke, T.; Clotet, B.; Howell, B. J.; Brander, C.; Mothe, B.; G Prado, J.

10.1101/2024.07.05.601669 — immunology — Posted on 2024-07-06

4135 Bayesian phylodynamics of early vertebrate development in BEAST 2

Zwaans, A.; Seidel, S.; Manceau, M.; Stadler, T.

10.1101/2024.07.04.601658 — bioinformatics — Posted on 2024-07-06

4136 SPArrOW: a flexible, interactive and scalable pipeline for spatial transcriptomics analysis

Pollaris, L.; Vanneste, B.; Rombaut, B.; Defauw, A.; Vernaillen, F.; Mortier, J.; Vanhenden, W.; Thone, T.; Martens, L.; Hastir, J.-F.; Bujko, A.; Saelens, W.; Marine, J.-C.; Nelissen, H.; Van Hamme, E.; Seurinck, R.; Scott, C. L.; Guilliams, M.; Saeys, Y.

10.1101/2024.07.04.601829 — bioinformatics — Posted on 2024-07-06

4137 3D Printed Multifunctional Bioadhesive Patch with Intrinsic Bioelectronic Properties for Decoding Electromechanical and Anisotropic Cardiac Microenvironment

Dutta, S. D.; Patil, T. V.; Lim, K.-T.

10.1101/2024.07.05.601338 — bioengineering — Posted on 2024-07-06

4138 Dokdo sea lion Zalophus japonicus genome reveals its evolutionary trajectory before extinction

Kim, J.; Blazyte, A.; Choi, J.-P.; Kim, C.; Sharko, F.; Jeon, S.; Kim, E.-M.; Sohn, H.; Lee, J. H.; Kim, H. W.; Yoo, M. H.; Lee, K.; Nedoluzhko, A.; Bhak, J.

10.1101/2024.07.04.602024 — genomics — Posted on 2024-07-06

4139 Novel Endogenous Retroviruses in Anura

Free, H. B.; Nichols, R. A.; Kanda, R. K.

10.1101/2024.07.05.601823 — genomics — Posted on 2024-07-06

4140 Evolutionary new centromeres in the snowy owl genome putatively seeded from a transposable element

Baalsrud, H. T.; Garmann-Aarhus, B.; Enevoldsen, E. L. G.; Krabberod, A. K.; Fischer, D.; Tooming-Klunderud, A.; Skage, M.; Arnyasi, M.; Sandve, S. R.; Jakobsen, K. S.; Nielsen, R.; Boessenkool, S.; Torresen, O. K.

10.1101/2024.07.05.602039 — genomics — Posted on 2024-07-06

4141 Repeat-rich regions cause false positive detection of NUMTs - a case study in amphibians using an improved cane toad reference genome

Cheung, K.; Rollins, L. A.; Hammond, J. M.; Barton, K.; Ferguson, J. M.; Eyck, H. J. F.; Shine, R.; Edwards, R. J.

10.1101/2024.07.04.601973 — genomics — Posted on 2024-07-06

4142 Deciphering the variation in cuticular hydrocarbon profiles of five European honey bee subspecies

Rodriguez-Leon, D. S.; Uzunov, A.; Costa, C.; Dylan, E. S.; Charistos, L.; Galea, T.; Gabel, M.; Scheiner, R.; Pinto, M. A.; Schmitt, T.

10.1101/2024.07.05.601031 — evolutionary biology — Posted on 2024-07-06

4143 Insights into gene conversion and crossing-over processes from long-read sequencing of human, chimpanzee and gorilla testes and sperm

Porsborg, P. S.; Charmouh, A. P.; Singh, V.; Winge, S. B.; Hvilsom, C.; Pelizzola, M.; Laurentino, S.; Neuhaus, N.; Hobolth, A.; Bataillon, T.; Almstrup, K.; Besenbacher, S.; Schierup, M. H.

10.1101/2024.07.05.601967 — evolutionary biology — Posted on 2024-07-06

4144 Distinct modes of holobiont specialization among cryptic coral lineages

Grupstra, C. G. B.; Meyer-Kaiser, K. S.; Bennett, M.-J.; Andres, M. O.; Juszkiewicz, D. J.; Fifer, J. E.; Da-Anoy, J. P.; Gomez-Campo, K.; Martinez-Rugerio, I.; Aichelman, H. E.; Huzar, A. K.; Hughes, A. M.; Rivera, H. E.; Davies, S. W.

10.1101/2024.07.05.598868 — ecology — Posted on 2024-07-06

4145 Food texture preference reveals multisensory contributions of gustatory organs in behaviour and physiology

Komarov, N.; Fritsch, C.; Maier, G. L.; Bues, J.; Biocanin, M.; Avalos, C. B.; Dodero, A.; Kwon, J. Y.; Deplancke, B.; Sprecher, S. G.

10.1101/2024.07.04.602043 — neuroscience — Posted on 2024-07-06

4146 Pan-cortical cellular imaging in freely behaving mice using a miniaturized micro-camera array microscope (mini-MCAM)

Hu, J.; Cherkkil, A.; Surinach, D. A.; Oladepo, I.; Hossain, R. F.; Fausner, S.; Saxena, K.; Ko, E.; Peters, R.; Feldkamp, M.; Konda, P. C.; Pathak, V.; Horstmeyer, R.; Kodandaramaiah, S. B.

10.1101/2024.07.04.601964 — neuroscience — Posted on 2024-07-06

4147 Generative deep learning models for cognitive performance trajectories in real-world scenarios

Exposito Navarro, D.; Maltseva, E.; Sastre-Barrios, C.; Fernandez de Pierola, I.; Cortes, J.

10.1101/2024.07.05.600608 — neuroscience — Posted on 2024-07-06

4148 Brain virtual histology of a lizard species (Podarcis bocagei) using X-ray micro-tomography and deep-learning segmentation

Zhou, T.; Dragunova, Y.; Triki, Z.

10.1101/2024.07.05.602071 — zoology — Posted on 2024-07-06

4149 Cybernetic control of a natural microbial co-culture

Lee, T. A.; Morlock, J.; Allan, J.; Steel, H.

10.1101/2024.07.04.602068 — systems biology — Posted on 2024-07-06

4150 Algal growth and morphogenesis-promoting factors released by cold-adapted bacteria contribute to the resilience and morphogenesis of the seaweed Ulva (Chlorophyta) in Antarctica (Potter Cove)

Ghaderiardakani, F.; Ulrich, J. F.; Barth, E.; Quartino, M. L.; Wichard, T.

10.1101/2024.07.05.601910 — plant biology — Posted on 2024-07-06

4151 SOX21 suppresses GBM growth by repressing AP-1 regulated target genes

Muhr, J.; Rrapaj, E.; Yuan, J.; Kurtsdotter, I.; Misyurin, V.; Baselli, G.; Persson, O.; Bergsland, M.

10.1101/2024.07.05.601643 — cancer biology — Posted on 2024-07-06

4152 Integrated Analysis of Single-Cell and Bulk RNA-Seq Data reveals that Ferroptosis-Related Genes Mediated the Tumor Microenvironment predicts Prognosis, and guides Drug Selection in Triple-Negative Breast Cancer

Gong, X.; Gu, L.; Yang, D.; He, Y.; Li, Q.; Qin, H.; Wang, Y.

10.1101/2024.07.04.602021 — cancer biology — Posted on 2024-07-06

4153 N-acetyl-transferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in M. marinum

Jones, B. S.; Pareek, V.; Hu, D. D.; Weaver, S. D.; Syska, C.; Galfano, G.; Champion, M.; Champion, P. A.

10.1101/2024.07.05.602253 — microbiology — Posted on 2024-07-06

4154 Walking entrains unique oscillations for central and peripheral visual detection

Phan, C. K.; Davidson, M. J.; Alais, D.

10.1101/2024.07.04.602020 — neuroscience — Posted on 2024-07-06

4155 "Magnetic Sand" : Illusions of Interactivity

Shimojo, S.; Shimojo, K.; Shimojo, E.; Zheng, S.; Wu, D.-A.

10.1101/2024.07.03.598775 — neuroscience — Posted on 2024-07-06

4156 Evaluating theories of neural information integration during visual search

Leite, A.; Adeli, H.; McPeek, R. M.; Zelinsky, G. J.

10.1101/2024.07.03.601936 — neuroscience — Posted on 2024-07-06

4157 Reproductive success of inbred strain MV31 of the ctenophore Mnemiopsis leidyi in a self-sustaining inland laboratory culture system

Garg, P.; Frey, C.; Browne, W. E.; Plotkin, S. S.

10.1101/2024.07.03.601798 — zoology — Posted on 2024-07-06

4158 Natural field diagnosis and molecular confirmation of fungal and bacterial watermelon pathogens in Bangladesh: A case study from Natore and Sylhet district

Ferdous, R.

10.1101/2024.07.03.601980 — pathology — Posted on 2024-07-06

4159 Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse

Fu, R.; Su, H. A.; Tian, Y.; Chen, H.; Lu, D.

10.1101/2024.07.03.601978 — cancer biology — Posted on 2024-07-06

4160 Drugging Disordered Proteins by Conformational Selection to Inform Therapeutic Intervention

Levine, Z. A.; Bogin, B. A.

10.1101/2024.07.03.601611 — biophysics — Posted on 2024-07-06

4161 From a single sequence to evolutionary trajectories: protein language models capture the evolutionary potential of SARS-CoV-2 protein sequences

Lamb, K. D.; Hughes, J.; Lytras, S.; Koci, O.; Young, F.; Grove, J.; Yuan, K.; Robertson, D. L.

10.1101/2024.07.05.602129 — bioinformatics — Posted on 2024-07-06

4162 Structural Characterization of DNA Binding Domain of Essential Mammalian Protein TTF 1

Singh, G.; Bhopale, A. J.; Khatri, S.; Prakash, P.; Kumar, R.; Singh, S. M.; Singh, S. K.

10.1101/2024.07.05.602234 — biochemistry — Posted on 2024-07-06

4163 SYSTEMIC FRATAXIN DEFICIENCY CAUSES TISSUE-DEPENDENT IRON HOMEOSTASIS ALTERATIONS: IMPLICATIONS FOR FRIEDREICH ATAXIA

Pazos-Gil, M.; Medina-Carbonero, M.; Sanz-Alcazar, A.; Portillo-Carrasquer, M.; Oliveira, L.; Hernandez, G.; Sanchez, M.; Delaspre, F.; Cabiscol, E.; Ros, J.; Tamarit, J.

10.1101/2024.07.05.602088 — biochemistry — Posted on 2024-07-06

4164 Nanotiming: telomere-to-telomere DNA replication timing profiling by nanopore sequencing

Theulot, B.; Tourancheau, A.; Simonin Chavignier, E.; Jean, E.; Arbona, J.-M.; Audit, B.; Hyrien, O.; Lacroix, L.; Le Tallec, B.

10.1101/2024.07.05.602252 — genomics — Posted on 2024-07-06

4165 Stochastic Modeling of Biophysical Responses to Perturbation

Chari, T.; Gorin, G.; Pachter, L.

10.1101/2024.07.04.602131 — genomics — Posted on 2024-07-06

4166 Transposable Element Expression and Sub-cellular Dynamics During hPSC Differentiation to Endoderm, Mesoderm, and Ectoderm Lineages

Babarinde, I. A.; Fu, X.; Ma, G.; Li, Y.; Akinwole, M.; Zhou, X.; Hutchins, A. P.

10.1101/2024.07.03.602001 — genomics — Posted on 2024-07-06

4167 The complete mitogenome of an unidentified Oikopleura species

Wibisana, J. N.; Plessy, C.; Dierckxsens, N.; Masunaga, A.; Luscombe, N.

10.1101/2024.07.04.602139 — genomics — Posted on 2024-07-06

4168 No phenotypic consequences of archaic hominin alleles in present-day humans

Molz, B.; Lana Alberro, M.; Eising, E.; Schijven, D.; Alagöz, G.; Francks, C.; Fisher, S. E.

10.1101/2024.07.05.602242 — genetics — Posted on 2024-07-06

4169 Natural variation in starvation sensitivity maps to a point mutation in phospholipase IPLA2-VIA in Drosophila melanogaster

Rand, D. M.; Williams, S. B.; Franklin, B.; Lemieux, F. A.

10.1101/2024.07.05.602254 — genetics — Posted on 2024-07-06

4170 Quantifying Forest Biomass and Genetic Contribution using Light Detection and Ranging

Sano, H.; Miura, N.; Inamori, M.; Unno, Y.; Guo, W.; Isobe, S.; Kusunoki, K.; Iwata, H.

10.1101/2024.07.03.601985 — genetics — Posted on 2024-07-06

4171 Resolving the source of branch length variation in the Y chromosome phylogeny

Swiel, Y.; Kelso, J.; Peyregne, S.

10.1101/2024.07.05.602100 — genetics — Posted on 2024-07-06

4172 Recommendations for Population and Individual Diagnostic SNP Selection in Non-Model Species

Armstrong, E. E.; Li, C.; Campana, M. A.; Ferrari, T.; Kelley, J. L.; Petrov, D.; Solari, K. A.; Mooney, J. A.

10.1101/2024.07.03.601943 — evolutionary biology — Posted on 2024-07-06

4173 Species distribution modeling of the castor bean tick, Ixodes ricinus (Linnaeus, 1758), under current and future climates, with a special focus on Ukraine and Latvia

Tytar, V.; Kozynenko, I.; Pupins, M.; Skute, A.; Ceirans, A.; Nekrasova, O.

10.1101/2024.07.03.602006 — ecology — Posted on 2024-07-06

4174 Social clues in risky pools: Perceived conspecific rivals strongly modify individual oviposition decisions in response to larval predation and competition

Ramesh, A.; Sharma, M.; Isvaran, K.

10.1101/2024.07.03.602002 — ecology — Posted on 2024-07-06

4175 The first report on the effect of white and black truffle extracts on human semen parameters in vitro

Shelkovnikova, V.; Dmitrieva, M.; Malygina, E.; Imidoeva, N.; Belyshenko, A.; Morgunova, M.; Vlasova, A.; Telnova, T.; Batalova, A.; Martynova, E.; Axenov-Gribanov, D.

10.1101/2024.07.03.601846 — developmental biology — Posted on 2024-07-06

4176 The functional roles of zebrafish HoxA- and HoxD-related clusters in the pectoral fin development

Ishizaka, M.; Nakazawa, H.; Maeno, A.; Kanno, H.; Fujii, R.; Tani, T.; Oikawa, S.; Koita, R.; Kawamura, A.

10.1101/2024.07.05.600788 — developmental biology — Posted on 2024-07-06

4177 Mapping the human hematopoietic stem and progenitor cell hierarchy through integrated single-cell proteomics and transcriptomics

Furtwaengler, B.; Uresin, N.; Richter, S.; Schuster, M. B.; Barmpouri, D.; Holze, H.; Wenzel, A.; Gronbaek, K.; Theilgaard-Moench, K.; Theis, F. J.; Schoof, E. M.; Porse, B. T.

10.1101/2024.07.05.602277 — cell biology — Posted on 2024-07-06

4178 Integrating tDNA Epigenomics and Expression with Codon Usage Unravel an Intricate Connection with Protein Expression Dynamics in Trypanosoma cruzi

Silva, H. G. d. S.; Kimura, S.; de Lima, P. L. C. P.; Pires, D. d. S.; Waldor, M. K.; da Cunha, J. P.

10.1101/2024.07.04.602108 — cell biology — Posted on 2024-07-06

4179 Human-specific lncRNA TMEM9B-AS1 is downregulated in skeletal muscle of individuals with type 2 diabetes and regulates ribosomal biogenesis

Sen, I.; Smith, J. A. B.; Caria, E.; Savikj, M.; Lian, K.; Ellefsen, S.; Zierath, J. R.; Krook, A.

10.1101/2024.07.05.602204 — cell biology — Posted on 2024-07-06

4180 H3.3 deposition counteracts the replication-dependent enrichment of H3.1 at chromocenters in embryonic stem cells

Arfe, S.; Karagyozova, T.; Forest, A.; Hmidan, H.; Meshorer, E.; Quivy, J.-P.; Almouzni, G.

10.1101/2024.07.04.601905 — cell biology — Posted on 2024-07-06

4181 Loss of TLR9 expression in breast cancer tumour cells and its role in the cell cycle.

Sible, E.; Weitsman, G.; Amouya, S.; Roblot, G.; Marotel, M.; Pescarmona, R.; Bendriss-Vermare, N.; Gillet, C.; Walzer, T.; Ceesay, A.; Michallet, M.-C.; Caux, C.; Cosset, F.-L.; Al-alem, U.; Ng, T.; Hasan, U. A.

10.1101/2024.07.04.601915 — cell biology — Posted on 2024-07-06

4182 Cellular heterogeneity in hypertrophic burn scars in response to carbon dioxide laser therapy

Chen, Y.-Y.; Mahon, C.; Turner, J.; Smith, C. M.; Abdulsalam, A.; Amirize, E.; Prince, A.; Heagerty, A.; Roberts, C.; Croft, A.; Wilson, Y.; Moiemen, N.; Lord, J.

10.1101/2024.07.05.600800 — cell biology — Posted on 2024-07-06

4183 Fully-Automated Multicolour Structured Illumination Module for Super-resolution Microscopy

Wang, H.; Peter, B.; Ullom, J.; Shepherd, D. P.; Heintzmann, R. P.; Diederich, B.

10.1101/2024.07.04.601961 — cell biology — Posted on 2024-07-06

4184 CBP/p300 lysine acetyltransferases inhibit HIV-1 expression in latently infected T-cells

Horvath, R.; Sadowski, I.

10.1101/2024.07.05.602286 — molecular biology — Posted on 2024-07-06

4185 Influenza A defective viral genome production is altered by metabolites, metabolic signaling molecules, and cyanobacteria extracts

Agu, I.; Jose, I. R.; Diaz-Munoz, S. L.

10.1101/2024.07.04.602134 — microbiology — Posted on 2024-07-06

4186 Early-life Microbiome-Derived HCA Enhances Type 3 Immunity via FXR-dependent m6A RNA methylation

yang, z.; Lin, Z.; You, Y.; Zhang, M.; Gao, N.; Wang, X.; Peng, J.; Wei, H.

10.1101/2024.07.04.602137 — microbiology — Posted on 2024-07-06

4187 De novo synthesis of fatty acids in Archaea via an archaeal fatty acid synthase complex

Schmerling, C.; Zhou, X.; Goers, P. E.; Koestlbacher, S.; Kessenbrock, T.; Podlesainski, D.; Sybers, D.; Wang, K.; Lindas, A.-C.; Snoep, J. L.; Peeters, E.; Kaiser, M.; Ettema, T. J. G.; Meckelmann, S. W.; Braesen, C.; Siebers, B.

10.1101/2024.07.05.601840 — microbiology — Posted on 2024-07-06

4188 Transovarial transmission in field caught mosquitoes identifies a mechanism for the establishment of Usutu virus in a temperate country

Schilling, M.; Lawson, B.; Spiro, S.; Jagdev, M.; Vaux, A. G. C.; Bruce, R. C.; Johnston, C. J.; Abbott, A. J.; Wrigglesworth, E.; Pearce-Kelly, P.; Cunningham, A. A.; Medlock, J. M.; Johnson, N.; Folly, A. J.

10.1101/2024.07.05.602178 — microbiology — Posted on 2024-07-06

4189 Toxic Small Alarmone Synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr

Kurata, T.; Takegawa, M.; Ohira, T.; Syroegin, E. A.; Johansson, M. J. O.; Atkinson, G. C.; Polikanov, Y. S.; Garcia-Pino, A.; Suzuki, T.; Hauryliuk, V.

10.1101/2024.07.05.602228 — microbiology — Posted on 2024-07-06

4190 Surveillance of H5 HPAI in Michigan using retail milk

Lauring, A. S.; Martin, E. T.; Eisenberg, M. C.; Fitzsimmons, W. J.; Salzman, E.; Leis, A. M.; Lyon-Callo, S.; Bagdasarian, N.

10.1101/2024.07.04.602115 — microbiology — Posted on 2024-07-06

4191 Maternal diet alters offspring early life host-microbiota communication through goblet cells, resulting in long-lasting diseases susceptibility

Delaroque, C.; Bonazzi, E.; Huillet, M.; Ellero-Simatos, S.; Hao, F.; Patterson, A.; Chassaing, B.

10.1101/2024.07.05.602179 — microbiology — Posted on 2024-07-06

4192 Glycoengineering with neuraminic acid analogs to label lipooligosaccharides and detect native sialyltransferase activity in Gram-negative bacteria

Alvarado-Melendez, E. I.; de Jong, H.; Hartman, J. E. M.; Ong, J. Y.; Wosten, M. M. S. M.; Wennekes, T.

10.1101/2024.07.05.602201 — microbiology — Posted on 2024-07-06

4193 Altered B Cell Metabolic Pathways Characterize Type 1 Diabetes Progression

Conway, H.; Perez, D.; Swar-Eldahab, M.; Pignanelli, J.; Evans-Molina, C.; Felton, J. L.

10.1101/2024.07.03.601778 — immunology — Posted on 2024-07-06

4194 A lasting impact of serotonergic psychedelics on visual processing and behavior

West, C. L.; Bastos, G.; Duran, A.; Nadeem, S.; Ricci, D. A.; Rader, A. M.; Wargo, J. A.; Peterka, D. S.; Van Leeuwen, N.; Hamm, J. P.

10.1101/2024.07.03.601959 — neuroscience — Posted on 2024-07-06

4195 Co-Transplantation-Based Human-Mouse Chimeric Brain Models to Study Human Glial-Glial and Glial-Neuronal Interactions

Jin, M.; Ma, Z.; Zhang, H.; Papetti, A. V.; Dang, R.; Stillitano, A.; Goldman, S. A.; Jiang, P.

10.1101/2024.07.03.601990 — neuroscience — Posted on 2024-07-06

4196 Glia control experience-dependent plasticity in an olfactory critical period

Leier, H. C.; Foden, A. J.; Jindal, D. A.; Wilkov, A. J.; Van der Linden Costello, P.; Vanderzalm, P. J.; Coutinho-Budd, J.; Tabuchi, M.; Broihier, H. T.

10.1101/2024.07.05.602232 — neuroscience — Posted on 2024-07-06

4197 Molecular and cellular rhythms in excitatory and inhibitory neurons in the mouse prefrontal cortex

Burns, J. N.; Jenkins, A. K.; Yin, R.; Zong, W.; Vadnie, C. A.; DePoy, L.; Petersen, K. A.; Tsyglakova, M.; Scott, M. R.; Tseng, G.; Huang, Y. H.; McClung, C. A.

10.1101/2024.07.05.601880 — neuroscience — Posted on 2024-07-06

4198 Bayesian inference in arm posture perception

Peviani, V. C.; Joosten, M. G. A.; Miller, L. E.; Medendorp, W. P.

10.1101/2024.07.05.602180 — neuroscience — Posted on 2024-07-06

4199 Robustness of mitochondrial biogenesis and respiration explain aerobic glycolysis

Arunachalam, E.; Keber, F. C.; Law, R. C.; Kumar, C. K.; Shen, Y.; Park, J. O.; Wuehr, M.; Needleman, D. J.

10.1101/2024.07.04.601975 — systems biology — Posted on 2024-07-05

4200 Retrospective Analysis of the Effects of BWF Interdisciplinary Postdoctoral to Faculty Transition Awards on Future Funding Success

Sekhon, M. K.; Scott, M.; Green, C. L.; Rose, M.

10.1101/2024.07.05.602167 — scientific communication and education — Posted on 2024-07-05

4201 Hormonal dynamics reveal a stimulatory role for secretoneurin in zebrafish ovulation

Peng, D.; Lu, C.; Spadacini, V.; Mitchell, K.; Tan, Y.; Zhang, D.; Levavi-Sivan, B.; Hu, W.; Trudeau, V.

10.1101/2024.07.03.601258 — physiology — Posted on 2024-07-05

4202 Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy

Wang, Y.; Bergman, D. R.; Trujillo, E.; Fernald, A. A.; Li, L.; Pearson, A. T.; Sweis, R. F.; Jackson, T. L.

10.1101/2024.07.03.601920 — cancer biology — Posted on 2024-07-05

4203 Ketomimetic Medium Promotes Metastatic Disposition and Chemoresistance in Breast Cancer Cells through Hypersialylation and Lipid Synthesis

Kamra, M.; Chen, Y.-I.; Delgado, P.; Seeley, E.; Seidlits, S.; YEH, H.-C.; Brock, A.; Parekh, S. H.

10.1101/2024.07.03.601966 — cancer biology — Posted on 2024-07-06

4204 Translational control of cell plasticity drives 5-FU tolerance

CHALABI-DCHAR, M.; VILLERONCE, O.; RIPOLL, J.; VINCENT, A.; FENOUIL, T.; KHOUEIRY, R.; KUCHARCZAK, J.; JENTSCHEL, L.; CATEZ, F.; Vigneron, A. M.; TREGUIER, J.; MANDIER, C.; BOUCLIER, C.; VITRE, J.; LAGERQVIST, L.; CHOQUET, A.; HERCEG, Z.; MACHON, C.; GUITTON, J.; DAVID, A.; SOLARY, E.; Bernard, D.; MARTIN, N.; RIVALS, E.; DALLA VENEZIA, N.; Pannequin, J.; DIAZ, J.-J.

10.1101/2024.07.03.601826 — cancer biology — Posted on 2024-07-06

4205 A discrete sarcomere model reveals internal unbinding dynamics and conditions for regularity of spontaneous oscillatory contractions

Warmington, B.; Bloomfield-Gadelha, H.; Rossiter, J.

10.1101/2024.07.03.601948 — biophysics — Posted on 2024-07-06

4206 Active Loop Extrusion guides DNA-Protein Condensation

Takaki, R.; Savich, Y.; Brugues, J.; Julicher, F.

10.1101/2024.07.03.601883 — biophysics — Posted on 2024-07-06

4207 Mechanism of Proton Release during Water Oxidation in Photosystem II

Allgower, F.; Poverlein, M. C.; Rutherford, A. W.; Kaila, V. R. I.

10.1101/2024.07.03.602004 — biophysics — Posted on 2024-07-06

4208 Identifying Alzheimer's disease-related pathways based on whole-genome sequencing data

Wang, Y.; Liu, T.; He, Y.; Tang, Y.; Tan, P.; Huang, L.; Huang, D.; Wen, T.; Shao, L.; Wang, J.; Wang, Y.; Han, Z.

10.1101/2024.07.03.601830 — bioinformatics — Posted on 2024-07-05

4209 Adaptive adjustment of significance thresholds produces large gains in microbial gene annotations and metabolic insights

Kananen, K.; Veseli, I. A.; Quiles Perez, C. J.; Miller, S. E.; Eren, A. M.; Bradley, P. H.

10.1101/2024.07.03.601779 — bioinformatics — Posted on 2024-07-05

4210 CPIExtract: A software package to collect and harmonize small molecule and protein interactions

Piras, A.; Chenghao, S.; Sebek, M. L.; Ispirova, G.; Menichetti, G.

10.1101/2024.07.03.601957 — bioinformatics — Posted on 2024-07-05

4211 Setting up an institutional OMERO environment for bioimage data: perspectives from both facility staff and users

Jannasch, A. K.; Tulok, S.; Okafornta, C. W.; Kugel, T.; Bortolomeazzi, M.; Boissonnet, T.; Schmidt, C.; Vogelsang, A.; Dittfeld, C.; Tugtekin, S.-M.; Matschke, K. E.; Paliulis, L.; Lindemann, D.; Fabig, G.; Mueller-Reichert, T.

10.1101/2024.07.04.601832 — bioinformatics — Posted on 2024-07-06

4212 PlasGO: enhancing GO-based function prediction for plasmid-encoded proteins based on genetic structure

Ji, Y.; Shang, J.; Guan, J.; Zou, W.; Liao, H.; Tang, X.; Sun, Y.

10.1101/2024.07.03.602011 — bioinformatics — Posted on 2024-07-06

4213 Cloud-Connected Patch-Worn Auscultation Device for Chest Sound Monitoring

Downen, R. S.; Li, B.; Dong, Q.; Li, Z.

10.1101/2024.07.03.601965 — bioengineering — Posted on 2024-07-06

4214 Oriented nucleosome binding by the pioneer factor ELF2

Xiao, T.; Crowe-McAuliffe, C.; Ochmann, M.; Zhu, F.; Osmala, M.; Rogerson, C.; Cramer, P.; Dienemann, C.; Taipale, J.

10.1101/2024.05.24.595749 — biochemistry — Posted on 2024-07-05

4215 Discovery of the missing cytochrome P450 monooxygenase cyclases that conclude glyceollin biosynthesis in soybean

Khatri, P.; Kuflu, K.; McDowell, T.; Lin, J.; Kovinich, N.; Dhaubhadel, S.

10.1101/2024.07.04.602010 — biochemistry — Posted on 2024-07-06

4216 Structural details of helix-mediated TDP-43 C-terminal domain multimerization

Rizuan, A.; Shenoy, J.; Mohanty, P.; dos Passos, P. M.; Mercado Ortiz, J. F.; Bai, L.; Viswanathan, R.; Wang, S.-H.; Johnson, V.; Mamede, L. D.; Ayala, Y. M.; Ghirlando, R.; Mittal, J.; Fawzi, N. L.

10.1101/2024.07.05.602258 — biochemistry — Posted on 2024-07-06

4217 On the enigmatic null effect of global methylation perturbation

Edrei, Y.; Hellman, A.

10.1101/2024.07.03.601377 — genomics — Posted on 2024-07-05

4218 High-Resolution Multimodal Profiling of Human Epileptic Brain Activity via Explanted Depth Electrodes

Dwivedi, A.; Mariappan, A.; Sanfeliu, A.; Larkin, J.; Walsh, P.; Henshall, D.; Tiwari, V.

10.1101/2024.07.03.601925 — genomics — Posted on 2024-07-05

4219 Dynamics and Regulatory Roles of RNA m6A Methylation in Unbalanced Genomes

Zhang, S.; Liu, X.; Wang, R.; Wang, J.; Zhang, L.; Sun, L.

10.1101/2024.07.05.602246 — genomics — Posted on 2024-07-06

4220 Discovery of a novel albendazole-ivermectin refractory Trichuris species, T. hominis, in Côte d'Ivoire patients through fecal DNA metabarcoding

Venkatesan, A.; Chen, R.; Bär, M. A.; Schneeberger, P.; Reimer, B.; Hürlimann, E.; Coulibaly, J. T.; Ali, S. M.; Sayasone, S.; Soghigian, J.; Keiser, J.; Gilleard, J. S.

10.1101/2024.07.04.602123 — genomics — Posted on 2024-07-06

4221 Deciphering the cis-regulatory landscape of natural yeast Transcript Leaders

Akirtava, C.; May, G.; Mcmanus, J.

10.1101/2024.07.03.601937 — genomics — Posted on 2024-07-06

4222 Pan-cancer subclonal mutation analysis of 7,827 tumors predicts clinical outcome

Jiang, Y.; Montierth, M. D.; Yu, K.; Ji, S.; Guo, S.; Tran, Q.; Liu, X.; Shin, S. J.; Cao, S.; Li, R.; Tang, Y.; Lesluyes, T.; Kopetz, S.; Ajani, J.; Msaouel, P.; Subudhi, S. K.; Aparicio, A.; Sharma, P.; Shen, J. P.; Sood, A. K.; Tarabichi, M.; Wang, J. R.; Kimmel, M.; Loo, P. V.; Zhu, H.; Wang, W.

10.1101/2024.07.03.601939 — genomics — Posted on 2024-07-06

4223 VPS28 regulates triglyceride synthesis and is mediated by the ubiquitination pathway in a bovine mammary epithelial cell line and mouse model

liu, l.; Wang, J.; Zheng, X.; Zhang, Q.

10.1101/2024.07.04.602114 — genetics — Posted on 2024-07-05

4224 Gene regulatory network structure informs the distribution of perturbation effects

Aguirre, M.; Spence, J. P.; Sella, G.; Pritchard, J. K.

10.1101/2024.07.04.602130 — genetics — Posted on 2024-07-05

4225 Evaluating UCE data adequacy and integrating uncertainty in a comprehensive phylogeny of ants

Borowiec, M. L.; Zhang, Y. M.; Neves, K.; Ramahlo, M. O.; Fisher, B. L.; Lucky, A.; Moreau, C. S.

10.1101/2024.07.03.601921 — evolutionary biology — Posted on 2024-07-05

4226 Dynamic Expansions and Retinal Expression of Spectrally Distinct Short-Wavelength Opsin Genes in Sea Snakes.

Rossetto, I. H.; Ludington, A. J.; Simoes, B. F.; Van Cao, N.; Sanders, K. L.

10.1101/2024.07.03.602000 — evolutionary biology — Posted on 2024-07-05

4227 Copy number variation contributes to parallel local adaptation in an invasive plant

Wilson, J. R.; Battlay, P.; Bieker, V. C.; van Boheemen, L.; Connallon, T.; Martin, M. D.; Hodgins, K. A.

10.1101/2024.07.03.601998 — evolutionary biology — Posted on 2024-07-06

4228 Quantifying compositional variability in microbial communities with FAVA

Morrison, M. L.; Xue, K. S.; Rosenberg, N. A.

10.1101/2024.07.03.601929 — ecology — Posted on 2024-07-05

4229 An ornithological survey of Fergusson Island, D'Entrecasteaux Archipelago, Papua New Guinea, reveals new island records and noteworthy natural history observations

Boersma, J.; Gregg, J.; Nason, D.; Malesa, E.; Le Breton, C.; Ketaloya, S.; Iova, B.; Mittermeier, J. C.

10.1101/2024.07.03.601923 — ecology — Posted on 2024-07-05

4230 Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila

Huang, H.; Dong, P.; Li, Y.; Wang, Y.; Zhao, Q.; Lu, T.; Guo, T.; Ma, J.; Yang, B.; Wu, H.

10.1101/2024.07.03.601877 — developmental biology — Posted on 2024-07-05

4231 Migration of Kupffers vesicle derived cells is essential for tail morphogenesis in zebrafish embryos

Hoeksma, J.; Den Hertog, J.

10.1101/2024.07.04.602018 — developmental biology — Posted on 2024-07-06

4232 ATG5 is dispensable for ATG8ylation of cellular proteins

Ketteler, R.; Kiso, K.; von Chamier, L.; Agrotis, A.

10.1101/2024.07.03.601942 — cell biology — Posted on 2024-07-05

4233 A long-lived pool of PINK1 imparts a molecular memory of depolarisation-induced activity.

Pollock, L.; Georgiou, I. C.; Rusilowicz-Jones, E. V.; Clague, M. J.; Urbe, S.

10.1101/2024.07.03.601901 — cell biology — Posted on 2024-07-05

4234 Intravital imaging reveals glucose-dependent cilia movement in pancreatic islets in vivo

Melnyk, O.; Guo, J. K.; Li, Z. A.; Hughes, J. W.; Linnemann, A. K.

10.1101/2024.07.03.601879 — cell biology — Posted on 2024-07-05

4235 A general Bioluminescence Resonance Energy Transfer (BRET) protocol to measure and analyze protein interactions in mammalian cells

Duval, C. J.; Steffen, C. L.; Pavic, K.; Abankwa, D. K.

10.1101/2024.07.05.602189 — cell biology — Posted on 2024-07-05

4236 The role of ER exit sites in maintaining P-body organization and transmitting ER stress response during Drosophila melanogaster oogenesis

Milano, S. N.; Bayer, L. V.; Ko, J. J.; Casella, C. E.; Bratu, D. P.

10.1101/2024.07.03.601952 — cell biology — Posted on 2024-07-05

4237 Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway

Bu, X.; Ashby, N.; Vitali, T.; Lee, S.; Gottumukkala, A.; Yoon, K.; Tabbara, S.; Latham, P.; Teal, C.; Chung, I.

10.1101/2024.07.05.602223 — cell biology — Posted on 2024-07-06

4238 Population dynamics after pancreatitis dictates long-lasting epigenetic reprogramming and mediates tumor predisposition

Fantuz, M.; Liebig, J.; Fontana, G.; Carbone, C.; Iebba, V.; Lukassen, S.; Conrad, C.; Carrer, A.

10.1101/2024.07.04.600210 — cell biology — Posted on 2024-07-06

4239 Autophagy inhibition in intestinal stem cells favors enteroendocrine cell differentiation through Stat92E activity

Lacarriere-Keïta, C.; Nassari, S.; Jean, S.

10.1101/2024.07.05.602279 — cell biology — Posted on 2024-07-06

4240 Coordination of protein synthesis and decay in mammalian cells

Sun, M. S.; Martin, B.; Dembska, J.; Deluz, C.; Suter, D. M.

10.1101/2024.07.04.602056 — cell biology — Posted on 2024-07-06

4241 Mass Spectrometry-based Profiling of Single-cell Histone Post-translational Modifications to Dissect Chromatin Heterogeneity

Cutler, R.; Corveleyn, L.; Ctortecka, C.; Cantlon, J.; Jacome Vaca, S. A.; Deforce, D.; Vijg, J.; Dhaenens, M.; Papanastasiou, M.; Carr, S. A.; Sidoli, S.

10.1101/2024.07.05.602213 — molecular biology — Posted on 2024-07-06

4242 Cytoplasmic mRNA capping enzyme is regulated by hypoxia inducible factor HIF1α and controls stability of the target lncRNAs during hypoxia

Islam, S.; Mukherjee, C.

10.1101/2024.07.05.602207 — molecular biology — Posted on 2024-07-06

4243 Comprehensive Phenotyping of Extracellular Vesicles in Blood of Healthy Humans - Insights into Cellular Origin and Biological Variability

Holcar, M.; Maric, I.; Tertel, T.; Goricar, K.; Cegovnik Primozic, U.; Cerne, D.; Giebel, B.; Lenassi, M.

10.1101/2024.07.04.602156 — molecular biology — Posted on 2024-07-06

4244 An ecological-evolutionary perspective on the genomic diversity and habitat preferences of the Acidobacteriota

McReynolds, E.; Elshahed, M. S.; Youssef, N. H.

10.1101/2024.07.05.601421 — microbiology — Posted on 2024-07-05

4245 Subconcussive head impacts sustained during American football alter gut microbiome diversity and composition

Pelland, Z.; Zafar, A.; Ay, A.; Belanger, K. D.

10.1101/2024.07.05.602235 — microbiology — Posted on 2024-07-05

4246 The Enemy Within: how pathogen-free are your commercial specific pathogen-free mice?

Mark, D. R.; Trolan, M. Y.; Douce, G. R.; Roe, A. J.; McHugh, R. E.

10.1101/2024.07.05.602177 — microbiology — Posted on 2024-07-06

4247 Plasmodium falciparum SET10 is a histone H3 lysine K18 methyltransferase that participates in a chromatin modulation network crucial for intraerythrocytic development

Musabyimana, J.-P.; Musa, S.; Manti, J.; Distler, U.; Tenzer, S.; Ngwa, C. J.; Pradel, G.

10.1101/2024.07.05.602231 — microbiology — Posted on 2024-07-06

4248 TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk

Veleeparambil, M.; Wang, C.; Kessler, P. M.; Willard, B.; Sen, G. C.; Chattopadhyay, S.

10.1101/2024.07.03.601759 — immunology — Posted on 2024-07-05

4249 Whole-body PET imaging of SIV using anti-Env probes fails to reveal regions of specific uptake in rhesus macaques

Srinivasula, S.; Kim, I.; Jang, H.; DeGrange, P.; Brown, H.; Dalton, V.; Badralmaa, Y.; Natarajan, V.; Long, B.; Carrasquillo, J.; Di Mascio, M.

10.1101/2024.07.05.601545 — immunology — Posted on 2024-07-05

4250 Wild-type and single-O-antigen repeat outer-membrane vesicles induce equivalent protection against homologous and heterologous Salmonella challenge

Alshayea, A. I.; Jossi, S.; Marcial-Juarez, E.; Perez-Toledo, M.; Persaud, R.; Schager, A. E.; Larsen, D. N.; Gutishvili, G.; Pillaye, J.; Escobar-Riquelme, F.; Aksu, K.; Bryant, J. A.; Horsnell, W. G.; Banzhaf, M.; Kaczmarek, J. Z.; Hojrup, P.; C. Gumbart, J.; Henderson, I. R.; Bavro, V. N.; Lopez-Macias, C.; Cunningham, A. F.

10.1101/2024.07.03.601871 — immunology — Posted on 2024-07-05

4251 Bacterial vaginosis-driven changes in vaginal T cell phenotypes and their implications for HIV susceptibility

MacLean, F.; Tsegaye, A. T.; Graham, J. B.; Swarts, J. L.; Vick, S. C.; Potchen, N.; Cruz Talavera, I.; Warrier, L.; Dubrulle, J.; Schroeder, L. K.; Mar, C.; Thomas, K. K.; Mack, M.; Sabo, M. C.; Chohan, B. H.; Ngure, K.; Mugo, N.; Lingappa, J. R.; Lund, J. M.

10.1101/2024.07.03.601916 — immunology — Posted on 2024-07-05

4252 Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels

Giese, A. P. J.; Weng, W.-H.; Kindt, K. S.; Chang, V. H. H.; Montgomery, J. S.; Ratzan, E. M.; Beirl, A. J.; Aponte Rivera, R.; Lotthammer, J. M.; Walujkar, S.; Foster, M. P.; Zobeiri, O. A.; Holt, J. R.; Riazuddin, S.; Cullen, K. E.; Sotomayor, M.; Ahmed, Z. M.

10.1101/2023.05.26.542533 — neuroscience — Posted on 2024-07-05

4253 Poor Self-Reported Sleep is Associated with Prolonged White Matter T2 Relaxation in Psychotic Disorders

Yesilkaya, H. U.; Chen, X.; Watford, L.; McCoy, E.; Genc, I.; Du, F.; Ongur, D.; Yuksel, C.

10.1101/2024.07.03.601887 — neuroscience — Posted on 2024-07-05

4254 Apparent Diffusion Coefficient fMRI shines a new light on white matter resting-state connectivity, as compared to BOLD

de Riedmatten, I.; Spencer, A.; Olszowy, W.; Jelescu, I. O.

10.1101/2024.07.03.601842 — neuroscience — Posted on 2024-07-05

4255 A scene with an invisible wall - navigational experience shapes visual scene representation

Li, S. P. D.; Shao, J.; Lu, Z.; McCloskey, M.; Park, S.

10.1101/2024.07.03.601933 — neuroscience — Posted on 2024-07-05

4256 An orbitocortical-thalamic circuit suppresses binge alcohol-drinking.

Gimenez Gomez, P.; Le, T.; Zinter, M.; M'angale, P.; Duran Laforet, V.; Freels, T.; Pavchinskiy, R.; Molas, S.; Schafer, D.; Tapper, A.; Thomson, T.; Martin, G.

10.1101/2024.07.03.601895 — neuroscience — Posted on 2024-07-05

4257 Simultaneous dual-color calcium imaging in freely-behaving mice

Dong, Z.; Feng, Y.; Diego, K.; Baggetta, A. M.; Sweis, B. M.; Pennington, Z. T.; Lamsifer, S. I.; Zaki, Y.; Sangiuliano, F.; Philipsberg, P. A.; Morales-Rodriguez, D.; Kircher, D. M.; Slesinger, P.; Shuman, T.; Aharoni, D.; Cai, D. J.

10.1101/2024.07.03.601770 — neuroscience — Posted on 2024-07-05

4258 New Atg9 phosphorylation sites regulate autophagic trafficking in glia

Wang, L.; Yi, S.; Zhang, S.; Tsai, Y.-t.; Wang, H.; Ho, M. S.

10.1101/2024.07.03.601894 — neuroscience — Posted on 2024-07-05

4259 Retinal bipolar cells borrow excitability from electrically coupled inhibitory interneurons to amplify excitatory synaptic transmission

Yadav, S. C.; Ganzen, L.; Nawy, S.; Kramer, R. H.

10.1101/2024.07.03.601922 — neuroscience — Posted on 2024-07-05

4260 Hierarchical cortical plasticity in congenital sight impairment

Maimon-Mor, R. O.; Farahbakhsh, M.; Hedger, N.; Rider, A. T.; Anderson, E.; Rees, G.; Knapen, T.; Michaelides, M.; Dekker, T.

10.1101/2024.07.04.602138 — neuroscience — Posted on 2024-07-05

4261 Hippocampal-entorhinal cognitive maps and cortical motor system represent action plans and their outcomes

Barnaveli, I.; Vigano, S.; Reznik, D.; Haggard, P.; Doeller, C. F.

10.1101/2024.07.04.602119 — neuroscience — Posted on 2024-07-05

4262 Functional assessment of a kcnb1 knock-out zebrafish to model KCNB1-related neurodevelopmental and epileptic disorders

Robichon, L.; Bar, C.; Marian, A.; Lehmann, L.; Renault, S.; Kabashi, E.; Ciura, S.; Nabbout, R.

10.1101/2024.07.03.601913 — neuroscience — Posted on 2024-07-05

4263 Atypical chemokine receptor 3 regulates synaptic removal in disease astrocytes

10.1101/2024.07.03.601867 — neuroscience — Posted on 2024-07-05

4264 Ultra-high temporal resolution 4D angiography using arterial spin labeling with subspace reconstruction

Shen, Q.; Wu, W.; Chiew, M.; Ji, Y.; Woods, J. G.; Okell, T. W.

10.1101/2024.07.03.601977 — neuroscience — Posted on 2024-07-05

4265 Postprandial sleep in short-sleeping Mexican cavefish

Gallman, K.; Rastoge, A.; North, O.; O'Gorman, M.; Hutton, P.; Lloyd, E.; Warren, W. C.; Kowalko, J. E.; Duboue, E. R.; Rohner, N.; Keene, A. C.

10.1101/2024.07.03.602003 — neuroscience — Posted on 2024-07-05

4266 Simulating a medical expertise: a robust novel stress induction paradigm in chronic pain patients

Chiron, A.; Fernandez, A.; Schmidt, L.; Plaza Wuthrich, S.; Suter, M. R.; Leknes, S.; Berna, C.

10.1101/2024.07.03.601919 — neuroscience — Posted on 2024-07-05

4267 Genetic liability underlying reward-related comorbidity in psychiatric disorders involves the coincident functions of autism-linked ADGRL1 and hevin

Correoso-Brana, K. G.; Anesio, A.; Dumas, S.; Valjent, E.; Heck, N.; Vialou, V.; Boucard, A. A.

10.1101/2024.07.03.601736 — neuroscience — Posted on 2024-07-05

4268 The Role of Glucocorticoid and Nicotinic Acetylcholine Receptors in the Reward-Enhancing Effects of Nicotine in the ICSS Procedure in Male and Female Rats

Chellian, R.; Behnood-Rod, A.; Bruijnzeel, A.

10.1101/2024.07.03.601962 — neuroscience — Posted on 2024-07-06

4269 Diverse Calcium Signaling in Astrocytes: Insights from a Computational Model

Bezerra, T. O.; Roque, A. C.

10.1101/2024.07.03.601899 — neuroscience — Posted on 2024-07-06

4270 Taxonomy and nomenclature of the giant hummingbirds (Patagona spp.) (Aves: Trochilidae)

Williamson, J. L.; Gadek, C. R.; Robinson, B. W.; Bautista, E.; Bauernfeind, S. M.; Baumann, M. J.; Gyllenhaal, E. F.; Marra, P. P.; Ricote, N.; Singh, N. D.; Valqui, T.; Witt, C. C.

10.1101/2024.07.03.601580 — zoology — Posted on 2024-07-05

4271 Life Cycle and Morphogenetic Differentiation in Heteromorphic Cell Types of a Cosmopolitan Marine Microalga

Bousquet, L.; Fainsod, S.; Decelle, J.; Murik, O.; Chevalier, F.; Gallet, B.; Templin, R.; Schwab, Y.; Avrahami, Y.; Koplovitz, G.; Ku, C.; Frada, M.

10.1101/2024.07.03.601694 — plant biology — Posted on 2024-07-05

4272 Effects of n-Hexane and ethanol extract of Milicia excelsa stone on pain perception in Sodium Monoiodoacetate-induced Osteoarthritic Female Wistar Rats

Adegbe, S.; Abiodun, L. E.; Jimoh-Abdulghaffaar, H. O.; Adegoke, M.

10.1101/2024.07.03.601862 — physiology — Posted on 2024-07-05

4273 Evaluation of the efficacy of the protopine total alkaloids of Macleaya cordata (Willd.) R. Br. in controlling E. coli infection in broiler chickens

Dong, Z.; Xu, Y.; Liu, Z.; Zeng, J.

10.1101/2024.07.03.601902 — pharmacology and toxicology — Posted on 2024-07-05

4274 Basal Cambrian soft-bodied segmented bilaterians preserved as microbial pseudomorphs

Yang, X.; Wang, D.; Zhang, Z.; Wang, X.; Sun, J.; Hao, W.; Liu, Y.; Uesugi, K.; Komiya, T.; Han, J.

10.1101/2024.07.03.601876 — paleontology — Posted on 2024-07-05

4275 Aging promotes lung cancer metastasis through epigenetic ATF4 induction

Patel, A. A. H.; Dzanan, J.; Ali, K. X.; Eklund, E. A.; Alvarez, S. W.; Altinönder, I.; Raj, D.; Zowalaty, A. E. E.; Sayin, S. I.; Dankis, M.; Schwarz, M.; Jonasson, E.; Le Gal, K.; Albatrok, H.; Oloffson Bagge, R.; Härtlova, A.; Stahlberg, A.; Hallqvist, A.; Wiel, C.; Sayin, V. I.

10.1101/2024.07.03.601209 — cancer biology — Posted on 2024-07-05

4276 Microgravity stimulates network activity of 3D neuronal spheroids in an acoustic trap

Lecoq, P.-E.; Viraye, G.; Dupuis, C.; Benoit-Gonin, X.; Aider, J.-L.; Peyrin, J.-M.

10.1101/2024.07.03.601873 — biophysics — Posted on 2024-07-05

4277 Unsupervised learning elucidates the interplay between conformational flexibility and aggregation in synergistic antimicrobial peptides

Serian, M.; Mason, A. J.; Lorenz, C. D.

10.1101/2024.07.03.601908 — biophysics — Posted on 2024-07-05

4278 PEPCy: Photostable fluoromodules for live cell, super-resolution microscopy of surface proteins

Sasazawa, M.; Chimthanawala, A.; Zeng, R.; Kim, D.; Buchan, K.; Zhang, M.; Saurabh, S.

10.1101/2024.07.03.601615 — biophysics — Posted on 2024-07-05

4279 A DIY guide for image-based spatial transcriptomic: TLS as a case example

Defard, t.; DESRENTES, A.; Fouillade, C.; Mueller, F.

10.1101/2024.07.03.601914 — bioinformatics — Posted on 2024-07-05

4280 A safe and effective method for thin cornea cross-linking

Zhou, S.; Lin, Z.; Hong, Y.; Liao, Y.

10.1101/2024.07.03.601888 — bioengineering — Posted on 2024-07-05

4281 Spatial top-down proteomics for the functional characterization of human kidney

Zemaitis, K. J.; Fulcher, J. M.; Kumar, R.; Degnan, D. J.; Lewis, L. A.; Liao, Y.-C.; Velickovic, M.; Williams, S. M.; Moore, R. J.; Bramer, L. M.; Velickovic, D.; Zhu, Y.; Zhou, M.; Pasa-Tolic, L.

10.1101/2024.02.13.580062 — biochemistry — Posted on 2024-07-05

4282 From Acute to Persistent Infection: Revealing Phylogenomic Variations in Salmonella Agona

Waters, E. V.; Lee, W. W. Y.; Ismail Ahmed, A.; Chattaway, M.-A.; Langridge, G. C.

10.1101/2024.07.03.601855 — genomics — Posted on 2024-07-05

4283 The APOE isoforms differentially shape the transcriptomic and epigenomic landscapes of human microglia in a xenotransplantation model of Alzheimer's disease

Murphy, K. B.; Hu, D.; Wolfs, L.; Mancuso, R.; De Strooper, B.; Marzi, S. J.

10.1101/2024.07.03.601874 — genomics — Posted on 2024-07-05

4284 Characterization of diatom communities in restored sewage channels in the Boye catchment, Germany

Mayombo, N. A. S.; Haverbeck, L. S.; Dani, M.; Kloster, M.; Vidakovic, D.; Beszteri, B.; Burfeid-Castellanos, A. M.

10.1101/2024.07.03.601863 — ecology — Posted on 2024-07-05

4285 Torque Teno Sus Virus 1: A Potential Surrogate Pathogen to Study Pig-Transmitted Transboundary Animal Diseases

Li, X.; Parker, B.; Boughton, R.; Beasley, J.; Smyser, T. J.; Austin, J.; Pepin, K.; Miller, R. S.; VerCauteren, K. C.; Wisely, S. M.

10.1101/2024.07.03.601911 — ecology — Posted on 2024-07-05

4286 Substrate stiffness modulates the emergence and magnitude of senescence phenotypes in dermal fibroblasts

Starich, B.; Yang, F.; Tanrioven, D.; Kung, H.-C.; Baek, J.; Nair, P. R.; Kamat, P.; Macaluso, N.; Eoh, J.; Han, K. S.; Gu, L.; Walston, J.; Sun, S.; Wu, P.-H.; Wirtz, D.; Phillip, J. M.

10.1101/2024.02.06.579151 — molecular biology — Posted on 2024-07-05

4287 Pathophysiology of hypereosinophilia-associated heart disease

Sunusi, U.; Ziegelmeyer, B.; Osuji, I.; Medvedovic, M.; Todd, H.; Abou-Khalil, J.; Zimmermann, N.

10.1101/2024.07.03.601845 — immunology — Posted on 2024-07-05

4288 Neurocomputational Mechanisms Underlying Maladaptive Self-Belief Formation in Depression

Czekalla, N.; Schröder, A.; Mayer, A. V.; Stierand, J.; Stolz, D. S.; Kube, T.; Korn, C. W.; Wilhelm-Groch, I.; Klein, J. P.; Paulus, F. M.; Krach, S.; Müller-Pinzler, L.

10.1101/2024.05.09.593087 — neuroscience — Posted on 2024-07-05

4289 Sex differences in change-of-mind neuroeconomic decision-making is modulated by LINC00473 in medial prefrontal cortex

Durand-de Cuttoli, R.; Issler, O.; Yakubov, B.; Jahan, N.; Abid, A.; Kasparov, S.; Granizo, K.; Ahmed, S.; Russo, S. J.; Nestler, E. J.; Sweis, B. M.

10.1101/2024.05.08.592609 — neuroscience — Posted on 2024-07-05

4290 Abrupt and gradual changes in neuronal processing upon falling asleep and awakening

Marmelshtein, A.; Lavy, B.; Hadad, B.; Nir, Y.

10.1101/2024.02.06.579189 — neuroscience — Posted on 2024-07-05

4291 Entorhinal cortex vulnerability to human APP expression promotes hyperexcitability and tau pathology

Goettemoeller, A. M.; Banks, E.; Kumar, P.; Olah, V. J.; McCann, K. E.; South, K.; Ramelow, C. C.; Eaton, A.; Duong, D. M.; Seyfried, N. T.; Weinshenker, D.; Rangaraju, S.; Rowan, M. J.

10.1101/2023.11.06.565629 — neuroscience — Posted on 2024-07-05

4292 Flexible neural representations of abstract structural knowledge in the human Entorhinal Cortex

Mark, S.; Baram, A.; Schwartenbeck, P.; Hahamy, A.; Samborska, V.; Behrens, T. E. J.

10.1101/2023.08.31.555760 — neuroscience — Posted on 2024-07-05

4293 Working smarter, not harder: silencing LAZY1 in Prunus domestica causes outward, wandering branch orientations with commercial and ornamental applications.

Kohler, A. R.; Hollender, C. A.; Raines, D.; Demuth, M.; Dardick, C.

10.1101/2024.07.03.601917 — plant biology — Posted on 2024-07-05

4294 Niche-Based Priority Effects Predict Microbe Resistance to Erwinia amylovora in Pear Nectar

McDaniel, C. S.; Vannette, R. L.; Arroyo-Flores, A.; Boundy-Mills, K. L.; Crowder, D. W.; Grilley, M. M.; Pathak, H.; Schaeffer, R. N.

10.1101/2024.07.03.601912 — plant biology — Posted on 2024-07-05

4295 Cryo-EM structures of a bathy phytochrome histidine kinase reveal a unique light-dependent activation mechanism

Bodizs, S. A.; Meszaros, P.; Grunewald, L.; Takala, H.; Westenhoff, S.

10.1101/2024.05.17.594632 — biochemistry — Posted on 2024-07-05

4296 Methods for constructing and evaluating consensus genomic interval sets

Rymuza, J.; Sun, Y.; Zheng, G.; LeRoy, N. J.; Murach, M.; Phan, N.; Zhang, A.; Sheffield, N. C.

10.1101/2023.08.03.551899 — genomics — Posted on 2024-07-05

4297 ZIP13 regulates lipid metabolism by changing intracellular iron and zinc balance

10.1101/2024.07.03.601606 — cell biology — Posted on 2024-07-05

4298 Microbiome turnover during offspring development varies with maternal care, but not moult, in a hemimetabolous insect

Cheutin, M.-C.; Boucicot, M.; Meunier, J.

10.1101/2024.03.26.586808 — microbiology — Posted on 2024-07-05

4299 Neonatal microbiota colonization drives maturation of primary and secondary goblet cell mediated protection in the pre-weaning colon

Johansson, A.; Venkita Subramani, M.; Yilmaz, B.; Nystrom, E.; Layunta, E.; Arike, L.; Sommer, F.; Rosenstiel, P.; Vereecke, L.; Manneras Holm, L.; Wullaert, A.; Pelaseyed, T.; Johansson, M. E. V.; Birchenough, G. M. H.

10.1101/2024.07.03.601781 — immunology — Posted on 2024-07-05

4300 Autoregulation of cluster root and nodule development by white lupin CCR1 receptor-like kinase

Marques, L.; Divol, F.; Boultif, A.; Garcia, F.; Soriano, A.; Maurines-Carboneill, C.; Fernandez, V.; Verstraeten, I.; Pidon, H.; Izquierdo, E.; Hufnagel, B.; Peret, B.

10.1101/2024.07.04.602037 — plant biology — Posted on 2024-07-05

4301 Phosphorylation-Dependent Activation of the bHLH Transcription Factor ICE1/SCRM Promotes Polarization of the Arabidopsis Zygote

Chen, H.; Xiong, F.; Bischoff, T.; Wang, K.; Miao, Y.; Slane, D.; Schwab, R.; Laux, T.; Bayer, M.

10.1101/2024.07.03.601926 — plant biology — Posted on 2024-07-05

4302 CarboTag: a modular approach for live and functional imaging of plant cell walls

Besten, M.; Hendriksz, M.; Michels, L.; Charrier, B.; Smakowska-Luzan, E.; Weijers, D.; Borst, J. W.; Sprakel, J.

10.1101/2024.07.05.597952 — plant biology — Posted on 2024-07-05

4303 Structurally diverse calloses/β-1,3-glucans in plant cell wall microdomains

Amsbury, S.; Marcus, S. E.; Yeshvekar, R.; Barber, J.; German, L.; Ross, J. F.; Lelenaite, I.; de Souza Moraes, T.; Wickramanayake, J.; Klebanovych, A.; Czymmek, K.; Burch-Smith, T. M.; Bayer, E. M.; Willats, W.; Manfield, I. W.; Knox, P.; Benitez-Alfonso, Y.

10.1101/2024.07.04.602027 — plant biology — Posted on 2024-07-05

4304 MAP4K1 and MAP4K2 regulate ABA-induced and Ca2+-mediated stomatal closure in Arabidopsis

Yamashita, K.; Katagiri, S.; Takase, H.; Li, Y.; Otoguro, A.; Kamiyama, Y.; Yamauchi, S.; Takemiya, A.; Mori, I. C.; Umezawa, T.

10.1101/2024.07.05.602132 — plant biology — Posted on 2024-07-05

4305 Integrating Gene Expression Analysis and Ecophysiological Responses to Water Deficit in Leaves of Tomato Plants

Bortolami, G.; de Werk, T. A.; Larter, M.; Thonglim, A.; Mueller-Roeber, B.; Balazadeh, S.; Lens, F.

10.1101/2024.07.05.602262 — plant biology — Posted on 2024-07-05

4306 Spatial Transcriptomics Reveals a Myeloma Cell Architecture with Dysfunctional T-Cell Distribution, Neutrophil Traps, and Inflammatory Signaling

Sudupe, L.; Muinos-Lopez, E.; Lopez-Perez, A. R.; Vilas-Zornoza, A.; Sarvide, S.; Ripalda-Cemborain, P.; Aguirre-Ruiz, P.; San Martin-Uriz, P.; Larrayoz, M.; Alvarez-Gigli, L.; Abengozar-Muela, M.; Cenzano, I.; Cocera, M.; Ruiz, J.; Sancho Gonzalez, I.; Bantan, A.; Kurowska, A.; Ye, J.; Newton, P. T.; Paiva, B.; Rodriguez-Madoz, J. R.; Lagani, V.; tegner, j.; Saez, B.; Martinez-Climent, J. A.; Calvo Arnedo, I.; Gomez-Cabrero, D.; Prosper, F.

10.1101/2024.07.03.601833 — cancer biology — Posted on 2024-07-05

4307 Alzheimer Disease Knowledge Graph Enhances Knowledge Discovery and Disease Prediction

Yang, Y.; Zhu, H.; Yu, K.; Gao, S.; Yu, S.; Xiong, D.; Qin, C.; Chen, H.; Tang, J.; Tang, N.

10.1101/2024.07.03.601339 — bioinformatics — Posted on 2024-07-05

4308 GelMetrics: An algorithm for analyzing the dynamics of gel-like phase separated condensates

Granik, N.; Amit, R.

10.1101/2024.07.03.601857 — bioinformatics — Posted on 2024-07-05

4309 Mitochondrial genomes of three Melampus species (Ellobiidae; Gastropoda) and a proposed mitochondrial control region for Euthyneura

Inaebnit, T.; Tiedemann, R.; Dennis, A.

10.1101/2024.07.03.601860 — genomics — Posted on 2024-07-05

4310 UPF1 is required for gene expression in mitochondria and paternal mtDNA clearance during spermatogenesis

Wright, M. T.; Singh, A. K.; Dixon, H. L.; Price, E. M.; Connolly, E. C.; di Maio, A.; Barlow, J. P.; Catoni, M.; Fan, Y.; Brogna, S.

10.1101/2024.05.10.591322 — cell biology — Posted on 2024-07-05

4311 Dynamics of odor-source localization: Insights from real-time odor plume recordings and head-motion tracking in freely moving mice

Tariq, M. F.; Sterrett, S. C.; Moore, S.; Lane, L.; Perkel, D. J.; Gire, D. H.

10.1101/2023.11.10.566539 — neuroscience — Posted on 2024-07-05

4312 The SmARTR pipeline: a modular workflow for the cinematic rendering of 3D scientific imaging data

Macri, S.; Di-Poi, N.

10.1101/2024.07.03.601651 — zoology — Posted on 2024-07-05

4313 Comparative RNA profiling identifies stage-specific phasiRNAs and co-expressed Argonaute genes in Bambusoideae and Pooideae species

Belanger, S.; Zhan, J.; Yu, Y.; Meyers, B.

10.1101/2024.06.12.598608 — plant biology — Posted on 2024-07-05

4314 Exceptional longevity of mammalian ovarian and oocyte macromolecules throughout the reproductive lifespan

Bomba-Warczak, E. K.; Velez, K. M.; Zhou, L. T.; Guillermier, C.; Edassery, S.; Steinhauser, M. L.; Savas, J. N.; Elizabeth Duncan, F.

10.1101/2023.10.18.562852 — physiology — Posted on 2024-07-05

4315 IsRNAcirc: 3D structure prediction of circular RNAs based on coarse-grained molecular dynamics simulation

Jiang, H.; Xu, Y.; Tong, Y.; Zhang, D.; Zhou, R.

10.1101/2024.07.03.601849 — biophysics — Posted on 2024-07-05

4316 Drug-Target Interactions Prediction at Scale: the Komet Algorithm with the LCIdb Dataset

Guichaoua, G.; Pinel, P.; Hoffmann, B.; Azencott, C.-A.; Stoven, V.

10.1101/2024.02.22.581599 — bioinformatics — Posted on 2024-07-05

4317 Fast-scBatch: Batch Effect Correction Using Neural Network-Driven Distance Matrix Adjustment

Chen, F.; Tian, L.; Fei, T.; Yu, T.

10.1101/2024.06.25.600557 — bioinformatics — Posted on 2024-07-05

4318 Acoustic monitoring for tropical insect conservation

Riede, K.; Balakrishnan, R.

10.1101/2024.07.03.601657 — animal behavior and cognition — Posted on 2024-07-05

4319 Unique territorial and compartmental organization of chromosomes in the holocentric silkmoth

Gil, J.; Rosin, L. F.; Navarrete, E.; Chowdhury, N.; Abraham, S.; Cornilleau, G.; Lei, E. P.; Mozziconacci, J.; Mirny, L. A.; Muller, H.; Drinnenberg, I. A.

10.1101/2023.09.14.557757 — genomics — Posted on 2024-07-05

4320 Alignment Free Phylogeny Construction Using Maximum Likelihood Using k-mer Counts

Rahman, A. T. M. M.; Habib, S.; Islam, M. M.; Rahman, K. M.; Rahman, A.

10.1101/2023.12.05.570306 — evolutionary biology — Posted on 2024-07-05

4321 Temporal continuity of habitat strengthens covariation between plant and arbuscular mycorrhizal fungal communities

Shimono, A.; Taiki, I.; Shiga, H.; Uchiyama, K.; Yaida, Y. A.; Ushimaru, A.; Kenta, T.

10.1101/2024.07.03.601831 — ecology — Posted on 2024-07-05

4322 The values of ecosystem services inside and outside of protected areas in Eastern and Southern Africa

Buschke, F. T.; Capitani, C.

10.1101/2023.09.27.559741 — ecology — Posted on 2024-07-05

4323 Hierarchizing multi-scale environmental effects on agricultural pest population dynamics: a case study on the annual onset of Bactrocera dorsalis population growth in Senegalese orchards

Caumette, C.; Diatta, P.; Piry, S.; Chapuis, M.-P.; Faye, E.; Sigrist, F.; Martin, O.; Papaix, J.; Brevault, T.; Berthier, K.

10.1101/2023.11.10.566583 — ecology — Posted on 2024-07-05

4324 Intercellular adhesion boots collective cell migration through elevated membrane tension

Bijonowski, B. M.; Park, J.; Bergert, M.; Teubert, C.; Diz-Munoz, A.; Galic, M.; Wegner, S. V.

10.1101/2024.07.03.601828 — cell biology — Posted on 2024-07-05

4325 Live Cell Fluorescence Microscopy - From Sample Preparation to Numbers and Plots

Zahumensky, J.; Malinsky, J.

10.1101/2024.03.28.587214 — cell biology — Posted on 2024-07-05

4326 Deubiquitinase JOSD1 tempers hepatic proteotoxicity

CHAKRABARTI, P.; CHOWDHURY, S.; SEN, A.; DAS, D.

10.1101/2024.07.03.601825 — cell biology — Posted on 2024-07-05

4327 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy

Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Nair, V.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.

10.1101/2024.02.26.582201 — cell biology — Posted on 2024-07-05

4328 Profiling Tel1 Signaling Reveals a Non-Canonical Motif Targeting DNA Repair and Telomere Control Machineries

Comstock, W. J.; Sanford, E. J.; Navarro, M.; Smolka, M. B.

10.1101/2024.07.03.601872 — molecular biology — Posted on 2024-07-05

4329 Asymmetric learning and adaptability to changes in relational structure during transitive inference

Graham, T. A.; Spitzer, B.

10.1101/2024.07.03.601844 — neuroscience — Posted on 2024-07-05

4330 The bodily appearance of a virtual partner affects the activity of the action observation and action monitoring systems in a minimally interactive task

Pesci, U. G.; Moreau, Q.; Era, V.; Candidi, M.

10.1101/2024.07.03.601841 — neuroscience — Posted on 2024-07-05

4331 Harnessing early multimodal motor training to drive motor recovery and brain-wide structural reorganization after stroke

Teichert, M.; Gull, S.; Herrmann, K.-H.; Gaser, C.; Reichenbach, J. R.; Urbach, A.; Frahm, C.; Holthoff, K.; Witte, O. W.; Schmidt, S.

10.1101/2024.07.03.601837 — neuroscience — Posted on 2024-07-05

4332 Cross-validating the electrophysiological markers of early face categorization

Yildirim-Keles, F. Z.; Stacchi, L.; Caldara, R.

10.1101/2024.07.03.601129 — neuroscience — Posted on 2024-07-05

4333 Restoration of locus coeruleus noradrenergic transmission during sleep

Sima, J.; Zhang, Y.; Farriday, D.; Ahn, A. Y.-E.; Lopez, E. R.; Jin, C.; Harrell, J.; Darmohray, D.; Silverman, D.; Dan, Y.

10.1101/2024.07.03.601820 — neuroscience — Posted on 2024-07-05

4334 Multi-scale modelling of location- and frequency-dependent synaptic plasticity induced by transcranial magnetic stimulation in the dendrites of pyramidal neurons

Hananeia, N.; Ebner, C.; Galanis, C.; Cuntz, H.; Opitz, A.; Vlachos, A.; Jedlicka, P.

10.1101/2024.07.03.601851 — neuroscience — Posted on 2024-07-05

4335 An Alzheimer's disease-associated common regulatory variant in a PTK2B intron alters microglial function

Bello, E.; Long, K.; Iwama, S.; Steer, J.; Cooper, S. E.; Alasoo, K.; Kumasaka, N.; Schwartzentruber, J.; Panousis, N. I.; Bassett, A. R.

10.1101/2023.11.04.565613 — neuroscience — Posted on 2024-07-05

4336 Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians

Ireland, D.; Rabeler, C. S.; Rao, S. S.; Richardson, R. J.; Collins, E.-M. S.

10.1101/2024.07.03.601848 — pharmacology and toxicology — Posted on 2024-07-05

4337 A murine experimental model of the unique pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus

Rucavado, A.; Camacho, E.; Escalante, T.; Lomonte, B.; Fernandez, J.; Solano, D.; Quiros-Gutierrez, I.; Ramirez-Vargas, G.; Vargas, K.; Arguello, I.; Navarro, A.; Abarca, C.; Segura, A.; Florentin, J.; Kallel, H.; Resiere, D.; Neviere, R.; Gutierrez, J. M.

10.1101/2024.07.03.601850 — pharmacology and toxicology — Posted on 2024-07-05

4338 Mechanobiochemical finite element model to analyze impact-loading-induced cell damage, subsequent proteoglycan loss, and anti-oxidative treatment effects in articular cartilage

Kosonen, J. P.; Eskelinen, A. S. A.; Orozco, G. A.; Coleman, M. C.; Goetz, J. E.; Anderson, D. D.; Grodzinsky, A. J.; Tanska, P.; Korhonen, R. K.

10.1101/2024.07.03.601852 — biophysics — Posted on 2024-07-05

4339 Ion and water permeation through Claudin-10b paracellular channels

Berselli, A.; Alberini, G.; Benfenati, F.; Maragliano, L.

10.1101/2024.07.03.601692 — biophysics — Posted on 2024-07-05

4340 Dicarbonyl stress enhances tumor intravasation

Kumar, N.; Samanta, B.; M, J. K.; Raghunathan, V.; Sen, P.; Bhat, R.

10.1101/2024.07.03.601810 — bioengineering — Posted on 2024-07-05

4341 Mapping the blood vasculature in an intact human kidney using hierarchical phase-contrast tomography

Rahmani, S.; Jafree, D. J.; Lee, P. D.; Tafforeau, P.; Brunet, J.; Nandawar, S.; Jacob, J.; Bellier, A.; Ackermann, M.; Jonigk,, D. D.; Shipley, R. J.; Long, D. A.; Walsh, C. L.

10.1101/2023.03.28.534566 — bioengineering — Posted on 2024-07-05

4342 A chromosome-level genome assembly of Dracaena cambodiana and comparative genomics analysis highlights the distinct biological features of two resource species of dragon's blood

Xu, Y.; Peng, J.; Li, S.; Liu, Y.; Wen, D.; Jiang, J.; Rong, M.; Wei, W.; Wang, Q.; Jin, Y.; Yang, S.; Wang, S.; Wei, J.

10.1101/2024.07.03.601834 — genomics — Posted on 2024-07-05

4343 A CRISPR-Cas9-based system for the dose-dependent study of DNA double strand breaks sensing and repair

Coiffard, J.; Kumanski, S.; Santt, O.; Pardo, B.; Moriel-Carretero, M.

10.1101/2021.10.21.465387 — genetics — Posted on 2024-07-05

4344 Lost in the woods: shifting habitats can lead phylogeography astray

Neher, R. A.

10.1101/2024.07.03.601889 — evolutionary biology — Posted on 2024-07-05

4345 Harbouring Starships: the accumulation of large horizontal gene transfers in domesticated and pathogenic fungi

O'Donnell, S.; Rezende, G.; Vernadet, J.-P.; Snirc, A.; Ropars, J.

10.1101/2024.07.03.601904 — evolutionary biology — Posted on 2024-07-05

4346 Structure-based inference of eukaryotic complexity in Asgard archaea

Koestlbacher, S.; van Hooff, J. J. E.; Panagiotou, K.; Tamarit, D.; De Anda, V.; Appler, K. E.; Baker, B. J.; Ettema, T. J. G.

10.1101/2024.07.03.601958 — evolutionary biology — Posted on 2024-07-05

4347 Transcriptomic responses of gecarcinid land crabs to acute and prolonged desiccation stress

Watson-Zink, V. M.; Grosberg, R. K.; Lai, J.; Bay, R.

10.1101/2024.07.03.601969 — evolutionary biology — Posted on 2024-07-05

4348 WITHDRAWN: Unveiling the Family of Optimal Accelerations in Minimax Optimization and Fixed-Point Algorithms

Bartlett, P.; Li, C. J.; Wu, J.; Yu, B.

10.1101/2024.06.29.601352 — genetics — Posted on 2024-07-05

4349 Polyelectrolyte mannan from diatoms reshapes sunlit ocean microbiome

Krull, J.; Crawford, C. J.; Sidhu, C.; Solanki, V.; Bligh, M.; Rössler, L.; Singh, R. K.; Huang, G.; Robb, C. S.; Teeling, H. J.; Seeberger, P. H.; Schweder, T.; Hehemann, J.-H.

10.1101/2024.07.03.601839 — ecology — Posted on 2024-07-05

4350 WITHDRAWN: Influences of Formalin Gas on Gene Expression Level of Tumor Protein TP53 in the Liver and Kidney of the Quail (Coturnix coturnix)

Baqer kadhim, A.; Baghdady, E. F.; Al hachem, I. I.

10.1101/2023.08.28.554209 — cancer biology — Posted on 2024-07-05

4351 A novel method for reliably measuring miniature and spontaneous postsynaptic potentials/currents in whole-cell patch clamp recordings in the central nervous system

Dervinis, M.; Major, G.

10.1101/2022.03.20.485046 — neuroscience — Posted on 2024-07-05

4352 UltraCortex: Submillimeter Ultra-High Field 9.4 T Brain MR Image Collection and Manual Cortical Segmentations

Mahler, L.; Steiglechner, J.; Bender, B.; Lindig, T.; Ramadan, D.; Bause, J.; Birk, F.; Heule, R.; Charyasz, E.; Erb, M.; Kumar, V. J.; Hagberg, G. E.; Martin, P.; Lohmann, G.; Scheffler, K.

10.1101/2024.06.18.599541 — neuroscience — Posted on 2024-07-05

4353 A connectome manipulation framework for the systematic and reproducible study of structure-function relationships through simulations

Pokorny, C.; Awile, O.; Isbister, J. B.; Kurban, K.; Wolf, M.; Reimann, M. W.

10.1101/2024.05.24.593860 — neuroscience — Posted on 2024-07-05

4354 Full-length RNA transcript sequencing traces brain isoform diversity in house mouse natural populations

Zhang, W.; Guenther, A.; Gao, Y.; Ullrich, K. K.; Huettel, B.; Ahmad, A.; Duan, L.; Wei, K.; Tautz, D.

10.1101/2024.01.03.573993 — genomics — Posted on 2024-07-05

4355 ASTROGLIOSIS AND NEUROINFLAMMATION UNDERLIE SCOLIOSIS UPON CILIA DYSFUNCTION

10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-07-05

4356 Inhibition of the Notch signal transducer CSL by Pkc53E-mediated phosphorylation to fend off parasitic immune challenge in Drosophila

Deichsel, S.; Frankenreiter, L.; Fechner, J.; Gahr, B. M.; Zimmermann, M.; Mastel, H.; Preis, I.; Preiss, A.; Nagel, A. C.

10.1101/2023.06.16.545247 — developmental biology — Posted on 2024-07-05

4357 Placental malaria is associated with a TLR-Endothelin-3-oxidative damage response in human placenta tissues

Chenge, S.; Mbalitsi, M.; Ngure, H.; Obimbo, M.; Singoei, M.; Kangogo, M.; Kanoi, B. N.; Gitaka, J.; Kobia, F. M.

10.1101/2024.04.17.589949 — cell biology — Posted on 2024-07-05

4358 Inhibition of host N-myristoylation compromises the infectivity of SARS-CoV-2 due to Golgi-bypassing egress from lysosomes and endoplasmic reticulum

Saber, S. H.; Shaker, M. R.; Sng, J.; Yak, N.; Morrison, S. D.; Pars, S.; Zheng, H.; Pietrogrande, G.; Binder, T.; Lu, S.; Floetenmeyer, M.; Ojha, R.; Quirin, T.; Ruuska, J.; Smura, T.; Strandin, T.; Kant, R.; Kareinen, L.; Sironen, T.; Talbo, G. H.; Zhu, Y.; Short, K.; Mar, J. C.; Kallemeijn, W. W.; Tate, E. W.; Solari, R.; van Waardenberg, A. J.; Vapalahti, O.; Wolvetang, E. J.; Balistreri, G.; Joensuu, M.

10.1101/2023.03.03.530798 — microbiology — Posted on 2024-07-05

4359 Architecture of the Human Default Mode Network: Cytoarchitecture, Wiring and Signal Flow

Paquola, C.; Garber, M.; Fraessle, S.; Royer, J.; Zhou, Y.; Tavakol, S.; Rodriguez-Cruces, R.; Cabalo, D. G.; Valk, S. L.; Eickhoff, S.; Margulies, D. S.; Evans, A. C.; Amunts, K.; Jefferies, E.; Smallwood, J.; Bernhardt, B.

10.1101/2021.11.22.469533 — neuroscience — Posted on 2024-07-05

4360 Reconfiguration of the visual code and retinal cell type complement in closely related diurnal and nocturnal mice

Allen, A. E.; Hahn, J.; Richarson, R.; Pantiru, A.; Mouland, J.; Bano-Otalora, B.; Monavarfeshani, A.; Yan, W.; Williams, C.; Wynne, J.; Rodgers, J.; Milosavljevic, N.; Orlowska-Feuer, P.; Storchi, R.; Sanes, J. R.; Shekhar, K.; Lucas, R. J.

10.1101/2024.06.14.598659 — neuroscience — Posted on 2024-07-05

4361 Hidden origami in Trypanosoma cruzi nuclei highlights its nonrandom 3D genomic organization

Bellini, N. K.; de Lima, P. L. C.; Pires, D. d. S.; da Cunha, J. P. C.

10.1101/2024.07.01.601582 — genomics — Posted on 2024-07-05

4362 Visualizing the translation landscape in human cells at high resolution

Zheng, W.; Zhang, Y.; Wang, J.; Wang, S.; Chai, P.; Bailey, E. J.; Guo, w.; Devarkar, S. C.; Wu, S.; Lin, J.; Zhang, K.; Liu, J.; Lomakin, I. B.; Xiong, Y.

10.1101/2024.07.02.601723 — molecular biology — Posted on 2024-07-05

4363 Inhibition of influenza virus replication by artificial proteins (αReps) targeting its RNA-polymerase

Delmas, B.; Bessonne, M.; Morel, J.; Nevers, Q.; Urvoas, A.; Valerio-Lepiniec, M.; Crepin, T.; Minard, P.

10.1101/2024.07.03.601934 — microbiology — Posted on 2024-07-05

4364 The archaeal class Nitrososphaeria is a key player of the reproductive microbiome in sponges during gametogenesis

Turon, M.; Koutsouveli, V.; Conejero, M.; Taboada, S.; Verdes, A.; Lorente-Sorolla, J. M.; Diez-Vives, C.; Riesgo, A.

10.1101/2024.07.03.601946 — microbiology — Posted on 2024-07-05

4365 MYBPHL nonsense mutations have poor sarcomere binding, are degraded, and cause abnormal contraction

Alvarez-Arce, A.; Fritzmann, G.; Burnham, H.; Araujo, K.; Pena, A.; Wittenkeller, L.; Barefield, D. Y.

10.1101/2024.07.01.601577 — physiology — Posted on 2024-07-05

4366 Single-cell RNA sequencing of the holothurian regenerating intestine reveals the pluripotency of the coelomic epithelium

Medina-Feliciano, J. G.; Valentin-Tirado, G.; Luna-Martinez, K.; Miranda-Negron, Y.; Garcia-Arraras, J. E.

10.1101/2024.07.01.601561 — developmental biology — Posted on 2024-07-05

4367 YAP1 Contributes to The Development of Contractile Force and Sarcomere Maturation in Human Pluripotent Stem Cell Derived Cardiomyocytes

Vinarsky, V.; Pagliari, S.; Martino, F.; Mazzotti, C.; Jirakova, K.; Garlikova, Z.; Di Iuri, E.; Kytyr, D.; Benzoni, P.; Arici, M.; Metallo, A.; Zeevaert, K.; Wagner, W.; Rocchetti, M.; Forte, G.

10.1101/2024.07.02.601803 — cell biology — Posted on 2024-07-05

4368 Spatial transcriptomics unveils the in situ cellular and molecular hallmarks of the lung in fatal COVID-19

Garcia-Prieto, C.; Musulen, E.; Davalos, V.; Ferrer, G.; Grases, D.; Porta-Pardo, E.; Perez Mies, B.; Caniego Casas, T.; Palacios, J.; Saenz Sarda, X.; Englund, E.; Esteller, M.

10.1101/2024.07.03.601404 — pathology — Posted on 2024-07-04

4369 RNA-TorsionBERT: leveraging language models for RNA 3D torsion angles prediction

Bernard, C.; Postic, G.; Ghannay, S.; Tahi, F.

10.1101/2024.06.06.597803 — bioinformatics — Posted on 2024-07-05

4370 Accelerating Protein-Protein Interaction screens with reduced AlphaFold-Multimer sampling

Bellinzona, G.; Sassera, D.; Bonvin, A. M. J. J.

10.1101/2024.06.07.597882 — bioinformatics — Posted on 2024-07-05

4371 Female fruit flies use social cues to make egg clustering decisions

Churchill, E. R.; Fowler, E. K.; Friend, L. A.; Archetti, M.; Yu, D. W.; Bourke, A. F. G.; Chapman, T.; Bretman, A.

10.1101/2024.07.03.600353 — animal behavior and cognition — Posted on 2024-07-05

4372 Revisiting the impact of synthetic ORF sequences on engineered LINE-1 retrotransposition

Chan, D.; Workman, S.; Gerdes, P.; Han, J. S.; Boeke, J. D.; Faulkner, G. J.; Richardson, S. R.

10.1101/2022.08.29.505632 — molecular biology — Posted on 2024-07-04

4373 Regeneration recapitulates many embryonic processes, including reuse of developmental regulatory regions

Loubet-Senear, K.; Srivastava, M.

10.1101/2024.07.04.601589 — developmental biology — Posted on 2024-07-04

4374 Pathogenic Th17 cells in ZAP-70 mutant mice share T cell receptor features with Wild-type Tregs

Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.

10.1101/2024.03.01.582868 — immunology — Posted on 2024-07-04

4375 The Geometry and Dimensionality of Brain-wide Activity

Wang, Z.; Mai, W.; Chai, Y.; Qi, K.; Ren, H.; Shen, C.; Zhang, S.; Tan, G.; Hu, Y.; Wen, Q.

10.1101/2023.02.23.529673 — neuroscience — Posted on 2024-07-04

4376 Neurovascular coupling actively regulates context-dependent emotional adjustment

Ruan, J.; Quan, X.; Xie, H.; Zhang, Y.; Zhang, D.; Wang, W.; Zhao, B.; Lu, D.; Jia, J.-M.

10.1101/2023.02.13.527949 — neuroscience — Posted on 2024-07-04

4377 Mesolimbic local field potentials are modulated by motor control

Mann, L. G.; Qian, H.; Hughes, N. C.; Zhao, Z.; Singh, B.; Wang, Z.; Johnson, G. W.; Fulton, J. N.; Yan, B.; Kang, H.; Li, R.; Dawant, B. M.; Englot, D. J.; Constantinidis, C.; Roberson, S. W.; Claassen, D. O.; Bick, S. K.

10.1101/2024.07.02.601451 — neuroscience — Posted on 2024-07-04

4378 Linking functional and structural brain organisation with behaviour in healthy adults

Forde, N. J.; Llera, A.; Beckmann, C.

10.1101/2024.07.04.602076 — neuroscience — Posted on 2024-07-04

4379 Eyes robustly blink to musical beats like tapping

Wu, Y.; Teng, X.; Du, Y.

10.1101/2024.07.04.602077 — neuroscience — Posted on 2024-07-04

4380 LEAFY and WAPO1 jointly regulate spikelet number per spike and floret development in wheat

Paraiso, F.; Lin, H.; Li, C.; Woods, D. P.; Lan, T.; Burguener, G. F.; Tumelty, C.; Debernardi, J. M.; Joe, A.; Dubcovsky, J.

10.1101/2023.11.02.565263 — plant biology — Posted on 2024-07-04

4381 StarSignDNA: Signature tracing for accurate representation of mutational processes

Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Nakken, S.; Lingjaerde, O. C.; Hovig, E.

10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-07-04

4382 Increased female competition for males with enhanced foraging skills in Guinea baboons

O'Hearn, W. J.; Beckmann, J.; von Fersen, L.; Dal Pesco, F.; Mundry, R.; Keupp, S.; Diakhate, N.; Niederbremer, C.; Fischer, J.

10.1101/2024.07.04.602040 — animal behavior and cognition — Posted on 2024-07-04

4383 Genetic association data are broadly consistent with stabilizing selection shaping human common diseases and traits

Koch, E. M.; Connally, N. J.; Baya, N. A.; Reeve, M. P.; Daly, M. J.; Neale, B. M.; Lander, E. S.; Bloemendal, A.; Sunyaev, S. R.

10.1101/2024.06.19.599789 — genomics — Posted on 2024-07-04

4384 De novo acquisition of antibiotic resistance in six species of bacteria

Wang, X. H.; de Koster, A. H.; Koenders-van Sintanneland, B. B.; Jonker, M. J.; Brul, S.; ter Kuile, B. H.

10.1101/2024.07.03.601945 — microbiology — Posted on 2024-07-04

4385 Structural models predict a significantly higher binding affinity between the NblA protein of cyanophage Ma-LMM01 and the phycocyanin of Microcystis aeruginosa NIES-298 compared to the host homolog

Meza-Padilla, I.; McConkey, B. J.; Nissimov, J. I.

10.1101/2024.07.03.601984 — microbiology — Posted on 2024-07-04

4386 The Staphylococcus aureus small non-coding RNA IsrR regulates TCA cycle activity and virulence

Rios, G.; McReynolds, A. K. G.; Pagella, E. A.; Norambuena, J.; Briaud, P.; Zheng, V.; Munneke, M. J.; Kim, J.; Racine, H.; Carroll, R. K.; Zelzion, E.; Skaar, E. P.; Bose, J. L.; Parker, D.; Lalaouna, D.; Boyd, J. M.

10.1101/2024.07.03.601953 — microbiology — Posted on 2024-07-04

4387 Tuning Ultrasensitivity in Genetic Logic Gates using Antisense RNA Feedback

Engelmann, N.; Molderings, M.; Koeppl, H.

10.1101/2024.07.03.601968 — synthetic biology — Posted on 2024-07-04

4388 Development of a highly active engineered PETase enzyme for polyester degradation

Bhattacharya, S.; Castagna, R.; Estiri, H.; Upmanis, T.; Ricci, A.; Gautieri, A.; Parisini, E.

10.1101/2024.07.04.602061 — bioengineering — Posted on 2024-07-04

4389 Conserved loop of a phase modifier endows protein condensates with fluidity

Kawamukai, H.; Matsusaki, M.; Tanimoto, T.; Watabe, M.; Morishima, K.; Tomita, S.; Shinkai, Y.; Niwa, T.; Mannen, T.; Kumeta, H.; Nanaura, H.; Kato, K.; Mabuchi, T.; Aiba, Y.; Uehara, T.; Isozumi, N.; Hara, Y.; Kanemura, S.; Matsumura, H.; Sugie, K.; Ishimori, K.; Muraoka, T.; Sugiyama, M.; Okumura, M.; Mori, E.; Yoshizawa, T.; Saio, T.

10.1101/2024.07.03.601791 — biochemistry — Posted on 2024-07-04

4390 Challenges for error-correction coding in DNA data storage: photolithographic synthesis and DNA decay

Gimpel, A. L.; Stark, W. J.; Heckel, R.; Grass, R. N.

10.1101/2024.07.04.602085 — biochemistry — Posted on 2024-07-04

4391 E3 ligase recruitment by UBQLN2 protects substrates from proteasomal degradation

Scheutzow, A.; Thanthirige, S.; Siffer, G.; Wohlever, M. L.

10.1101/2024.07.04.602059 — biochemistry — Posted on 2024-07-04

4392 Female oviposition decisions are influenced by the microbial environment

Fowler, E. K.; Friend, L. A.; Churchill, E. R.; Yu, D. W.; Archetti, M.; Bourke, A. F. G.; Bretman, A.; Chapman, T.

10.1101/2024.07.03.601843 — evolutionary biology — Posted on 2024-07-04

4393 What determines the vertical structuring of pelagic ecosystems in the global ocean?

Belharet, M.; Lengaigne, M.; Barrier, N.; Brierley, A. S.; Irigoien, X.; Proud, R.; Maury, O.

10.1101/2024.07.04.602098 — ecology — Posted on 2024-07-04

4394 SEM-2/SoxC regulates multiple aspects of C. elegans postembryonic mesoderm development

Baccas, M.; Ganesan, V.; Leung, A.; Pineiro, L. R.; McKillop, A. N.; Liu, J.

10.1101/2024.07.04.602042 — developmental biology — Posted on 2024-07-04

4395 Dynamic Plk1 recruitment to the inner centromere

Norman, R. X.; Lera, R. F.; Mattix, A. A.; Shen, Z.; Carlsen, C. L.; Burkard, M. E.

10.1101/2024.07.03.601947 — cell biology — Posted on 2024-07-04

4396 Heuristic energy-based cyclic peptide design

Zhu, Q.; Mulligan, V. K.; Shasha, D. E.

10.1101/2024.07.03.601955 — molecular biology — Posted on 2024-07-04

4397 Activated RNAi does not rescue piRNA pathway deficiency in testes

Taborska, E.; Loubalova, Z.; Kulmann, M. I. R.; Malik, R.; Buccheri, V.; Pasulka, J.; Horvat, F.; Jenickova, I.; Sedlacek, R.; Svoboda, P.

10.1101/2024.07.04.602103 — molecular biology — Posted on 2024-07-04

4398 An emerging PB2-627 polymorphism increases the pandemic potential of avian influenza virus by breaking through ANP32 host restriction in mammalian and avian hosts

10.1101/2024.07.03.601996 — microbiology — Posted on 2024-07-04

4399 Alpine lakes harbor diverse, endemic and structurally unique RNA viruses

Wu, L.; Liu, Y.; Shi, W.; Chang, T.; Liu, P.; Liu, K.; He, Y.; Li, Z.; Shi, M.; Jiao, N.; Dong, X.; Zheng, Q.

10.1101/2024.07.04.601995 — microbiology — Posted on 2024-07-04

4400 Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor

Appler, K. E.; Lingford, J. P.; Gong, X.; Panagiotou, K.; Leao, P.; Langwig, M.; Greening, C.; Ettema, T. J. G.; De Anda, V.; Baker, B. J.

10.1101/2024.07.04.601786 — microbiology — Posted on 2024-07-04

4401 Resource competition in CRISPRa genetic circuits

Manoj, K.; Del Vecchio, D.

10.1101/2024.07.03.601429 — synthetic biology — Posted on 2024-07-04

4402 Sensitive detection of synthetic response to cancer immunotherapy driven by gene paralog pairs

Dong, C.; Zhang, F.; He, E.; Ren, P.; Verma, N.; Zhu, X.; Feng, D.; Zhao, H.; Chen, S.

10.1101/2024.07.02.601809 — bioinformatics — Posted on 2024-07-04

4403 G-quadruplex formation in long non-coding RNAs dysregulated in colorectal cancer

Sharma, S.; Shukla, C.; Mitteaux, J.; Pipier, A.; Pirrotta, M.; Penouilh, M.-J.; Monchaud, D.; Datta, B.

10.1101/2024.07.04.602106 — biochemistry — Posted on 2024-07-04

4404 SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring via IFN-gamma responsive microglia

Qi, F.; Yao, Z.

10.1101/2024.07.03.601972 — animal behavior and cognition — Posted on 2024-07-04

4405 Self-Organization of Sinusoidal Vessels in Pluripotent Stem Cell-derived Human Liver Bud Organoids

Saiki, N.; Nio, Y.; Yoneyama, Y.; Kawamura, S.; Iwasawa, K.; Kawakami, E.; Araki, K.; Fukumura, J.; Sakairi, T.; Ohmura, R.; Koido, M.; Funata, M.; Thompson, W. L.; Cruz-Encarnacion, P.; Chen, Y.-W.; Takebe, T.

10.1101/2024.07.02.601804 — developmental biology — Posted on 2024-07-04

4406 Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cells

Wu, W.; Lam, A. R.; Suarez, K.; Smith, G. N.; Duquette, S. M.; Yu, J.; Mankus, D.; Bisher, M.; Lytton-Jean, A.; Manalis, S. R.; Miettinen, T. P.

10.1101/2024.07.02.601447 — cell biology — Posted on 2024-07-04

4407 IL-13 decreases susceptibility to airway epithelial SARS-CoV-2 infection but increases disease severity in vivo

Ghimire, S.; Xue, B.; Li, K.; Gannon, R. M.; Wohlford-Lenane, C. L.; Thurman, A. L.; Gong, H.; Necker, G. C.; Zheng, J.; Meyerholz, D. K.; Perlman, S.; McCray, P. B.; Pezzulo, A. A.

10.1101/2024.07.03.601941 — cell biology — Posted on 2024-07-04

4408 Ixodes ricinus bites promote allergic skin inflammation and intestinal tuft and mast cell expansion in mice.

Leyva-Castillo, J. M.; Strakosha, M.; Smith, S. E. M.; Vega-Mendoza, D.; Elkins, M.; Chou, J.; Vogel, P.; Boulanger, N.

10.1101/2024.07.02.600632 — immunology — Posted on 2024-07-04

4409 Kinetic modeling of 18F-PI-2620 binding in the brain using an image-derived input function with total-body PET

Bhattarai, A.; Holy, E. N.; Wang, Y.; Spencer, B. A.; Wang, G.; DeCarli, C.; Fan, A. P.

10.1101/2024.07.02.601764 — neuroscience — Posted on 2024-07-04

4410 Prevalence of GIT nematodes and associated risk factors of exotic chickens in selected farm of poultry in and around Ambo, Ethiopia

Temesgen, A. B.; Wassie, Z. G.; Abebe, S.

10.1101/2024.07.02.601802 — pathology — Posted on 2024-07-04

4411 Cryo-EM of AKAP350 reveals fibrillar clusters and a potential association with DNA

Dai, D. L.; Keszei, A. F. A.; kolobova, e.; St-Germain, J.; Hasan, S. M. N.; Liu, A. C. H.; Zhang, X.; Raught, B.; Goldenring, J. R.; Mazhab-Jafari, M. T.

10.1101/2024.07.02.601773 — biochemistry — Posted on 2024-07-04

4412 Complement C5a receptor 1 blockade reverses cognitive deficits following cranialradiation therapy for brain cancer

Krattli, R. P.; Do, A. H.; El-Khatib, S. M.; Alikhani, L.; Markarian, M.; Vagadia, A. R.; Usmani, M. T.; Madan, S.; Baulch, J. E.; Clark, R. J.; Woodruff, T. M.; Tenner, A. J.; Acharya, M. M.

10.1101/2024.07.02.601806 — neuroscience — Posted on 2024-07-04

4413 BiRNA-BERT Allows Efficient RNA Language Modeling with Adaptive Tokenization

Tahmid, M. T.; Shahgir, H. S.; Mahbub, S.; Dong, Y.; Bayzid, M. S.

10.1101/2024.07.02.601703 — bioinformatics — Posted on 2024-07-04

4414 Spatial gene expression at single-cell resolution from histology using deep learning with GHIST

Fu, X.; Cao, Y.; Bian, B.; Wang, C.; Graham, D.; Pathmanathan, N.; Patrick, E.; Kim, J.; Yang, J. Y. H.

10.1101/2024.07.02.601790 — bioinformatics — Posted on 2024-07-04

4415 MAJIQ V3 offers improvements in accuracy, performance, and usability for splicing analysis from RNA sequencing

Aicher, J. K.; Slaff, B. M.; Jewell, S.; Barash, Y.

10.1101/2024.07.02.601792 — bioinformatics — Posted on 2024-07-04

4416 Compressive Pangenomics Using Mutation-Annotated Networks

Walia, S.; Motwani, H.; Smith, K.; Corbett-Detig, R.; Turakhia, Y.

10.1101/2024.07.02.601807 — bioinformatics — Posted on 2024-07-04

4417 Transcriptional landscape of a hypoxia response identifies cell-specific pathways for adaptation

Kong, J. N.; Ghosh, D. D.; Savvidis, A.; Sando, S. R.; Droste, R.; Horvitz, H. R.

10.1101/2024.07.02.601765 — genetics — Posted on 2024-07-04

4418 Genomic prediction of heterosis, inbreeding control, and mate allocation in outbred diploid and tetraploid populations

Endelman, J. B.

10.1101/2024.07.01.601581 — genetics — Posted on 2024-07-04

4419 Substrate Rigidity Modulates Segmentation Clock Dynamics in Isolated Presomitic Mesoderm Cells

Sung, C.-Y.; Kadiyala, U.; Blanchard, O.; Yourston, L.; Walker, D.; Li, L.; Fu, J.; Yang, Q.

10.1101/2024.07.02.601712 — developmental biology — Posted on 2024-07-04

4420 3D directional tuning in the orofacial sensorimotor cortex during natural feeding and drinking

Hosack, V. B.; Arce-McShane, F. I.

10.1101/2024.07.02.601741 — neuroscience — Posted on 2024-07-04

4421 Disruption of the PGE2 synthesis / response pathway restrains atherogenesis in programmed cell death-1 (Pd-1) deficient hyperlipidemic mice

Ricciotti, E.; Tang, S. Y.; Mrcela, A.; Das, U.; Lordan, R.; Joshi, R.; Ghosh, S.; Aoyama, J.; McConnell, R.; Yang, J.; Grant, G. R.; FitzGerald, G. A.

10.1101/2024.07.02.601762 — pharmacology and toxicology — Posted on 2024-07-04

4422 Memantine Inhibits Calcium-Permeable AMPA Receptors

Carrillo, E.; Montano Romero, A.; Gonzalez, C. U.; Turcu, A. L.; Chen, S.-R.; Chen, H.; Pan, H.-L.; Vazquez, S.; Twomey, E. C.; Jayaraman, V.

10.1101/2024.07.02.601784 — biophysics — Posted on 2024-07-04

4423 Biomolecular condensates are characterized by interphase electric potentials

Posey, A. E.; Bremer, A.; Erkamp, N. A.; Pant, A.; Knowles, T.; Dai, Y.; Mittag, T.; Pappu, R. V.

10.1101/2024.07.02.601783 — biophysics — Posted on 2024-07-04

4424 Prediction of single-cell chromatin compartments from single-cell chromosome structures by MaxComp

Zhan, Y.; Musella, F.; Alber, F.

10.1101/2024.07.02.600897 — bioinformatics — Posted on 2024-07-04

4425 Molecular characterization of response to etrolizumab and anti-TNF reveals treatment resistance in ulcerative colitis is associated with the abundance of residual neutrophil subsets and inflammatory fibroblast populations

Toghi Eshghi, S.; Gubatan, J. M.; Mazrooei, P.; Quintanilla, L.; Nguyen, A.; Au-Yeung, A.; Holman, D. R.; Takahashi, C.; Schiffman, C.; O'Gorman, W.; Keir, M.; Ramanujan, S.; Rogalla, S.; Hackney, J.; McBride, J. M.

10.1101/2024.07.02.601267 — immunology — Posted on 2024-07-04

4426 TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms

Dykstra, M. M.; Weskamp, K.; Gomez, N. B.; Waksmacki, J.; Tank, E. M.; Glineburg, M. R.; Snyder, A.; Pinarbasi, E.; Bekier, M.; Li, X.; Bai, J.; Shahzad, S.; Nedumaran, J.; Wieland, C.; Stewart, C.; Willey, S.; Grotewold, N.; McBride, J.; Moran, J.; Suryakumar, A.; Lucas, M.; Tessier, P.; Ward, M.; Todd, P.; Barmada, S.

10.1101/2024.07.02.601776 — neuroscience — Posted on 2024-07-04

4427 Differential Aging Effects on Implicit and Explicit Sensorimotor Learning

Cisneros, E.; Karny, S.; Ivry, R. B.; Tsay, J. S.

10.1101/2024.07.02.601091 — neuroscience — Posted on 2024-07-04

4428 Microglia mediate the early-life programming of adult glucose control

Valdearcos, M.; McGrath, E. R.; Brown Mayfield, S.; Folick, A.; Cheang, R. T.; Li, L.; Bachor, T. P.; Lippert, R. N.; Xu, A. W.; Koliwad, S. K.

10.1101/2024.07.02.601752 — physiology — Posted on 2024-07-04

4429 Alcohol induces p53-mediated apoptosis in neural crest by stimulating the AMPK-mediated suppression of TORC1, p70/S6K, and ribosomal biogenesis.

Huang, Y.; Flentke, G. R.; Smith, S. M.

10.1101/2024.07.02.601754 — pharmacology and toxicology — Posted on 2024-07-04

4430 Preclinical evaluation of pharmacological inhibition of SIRT1 on the growth of tumoral and metastatic granulosa cells

Cluzet, V.; Airaud, E.; Devillers, M. M.; Petit, F.; Leary, A.; Pierre, A.; Li, H.; Day, C.-P.; Weyemi, U.; Chauvin, S.; Guigon, C.

10.1101/2024.07.02.601506 — cancer biology — Posted on 2024-07-04

4431 Impact of PI3K pathway alterations on response to immune checkpoint inhibitors in HPV-negative head and neck squamous cell carcinoma

Park, J. C.; Basak, N. P.; Useche, M.; Park, J. S.; Mandakulutur, S. G.; Prabha, A.; Chandra Reddy, J.; Varvares, M.; Wirth, L.; Faquin, W.; Sankaran, S.; Saladi, S. V.

10.1101/2024.07.02.601738 — cancer biology — Posted on 2024-07-04

4432 Response of photosynthetic efficiency to short-term fluctuating light and cold in tomato

Rayaprolu, L.; Jayasankar, K.; Aarts, M. G. M.; Harbinson, J.

10.1101/2024.07.02.601750 — biophysics — Posted on 2024-07-04

4433 Metagenomic peek into a corn mummy

Solymosi, N.; Pap, B.; Nagy, S. A.; Toth, A. G.; Kevely, F. J.; Maroti, G.; Csabai, I.; Kothay, K.; Magyar, D.

10.1101/2024.07.02.601727 — bioinformatics — Posted on 2024-07-04

4434 Step Forward Cross Validation for Bioactivity Prediction: Out of Distribution Validation in Drug Discovery

Saha, U. S.; Vendruscolo, M.; Carpenter, A. E.; Singh, S.; Bender, A.; Seal, S.

10.1101/2024.07.02.601740 — bioinformatics — Posted on 2024-07-04

4435 BaCoN (Balanced Correlation Network) improves prediction of gene buffering

Rohde, T.; Demirtas, T. Y.; Shaw, A. H.; Billmann, M.

10.1101/2024.07.01.601598 — bioinformatics — Posted on 2024-07-04

4436 Metabolic Profiles of Encapsulated Chondrocytes Exposed to Short-Term Simulated Microgravity

Bergstrom, A. R.; Glmm, M. G.; Houske, E. A.; Cooper, G.; Viles, E.; Bourekis, K.; Welhaven, H. D.; Brahmachary, P. P.; Hahn, A. K.; June, R. K.

10.1101/2024.07.01.601604 — bioengineering — Posted on 2024-07-04

4437 Opto-Myomatrix: μLED integrated microelectrode arrays for optogenetic activation and electrical recording in muscle tissue

Lu, J.; Zia, M.; Baig, D. A.; Yan, G.; Kim, J. J.; Nagapudi, K.; Anschutz, P.; Oh, S.; O'Connor, D. H.; Sober, S. J.; Bakir, M. S.

10.1101/2024.07.01.601601 — bioengineering — Posted on 2024-07-04

4438 Evidence of a Slower-Z effect in Schistosoma japonicum

Mrnjavac, A.; Vicoso, B.

10.1101/2024.07.02.601697 — evolutionary biology — Posted on 2024-07-04

4439 Allopatric speciation in cattails: Genomic landscapes of divergence across Typha spp. suggest balancing selection, introgressions, and the absence of adaptive divergence

Aleman, A.; Freeland, J. R.; Shafer, A. B. A.; Dorken, M.

10.1101/2024.07.02.601742 — evolutionary biology — Posted on 2024-07-04

4440 Genomic Signatures of Domestication in a Fungus Obligately Farmed by Leafcutter Ants

Leal-Dutra, C. A.; Vizueta, J.; Baril, T.; Kooij, P. W.; Rodsgaard-Jorgensen, A.; Schantz-Conlon, B. H.; Shik, J. Z.

10.1101/2024.07.02.601708 — evolutionary biology — Posted on 2024-07-04

4441 Salinisation and warming disrupt predator-induced drift behaviour in aquatic predator-prey interactions

Vermiert, A.-M.; Madge Pimentel, I.; Rehsen, P. M.; Otto, T.; Horstmann, M.; Beermann, A. J.; Leese, F.; Weiss, L. C.; Tollrian, R.

10.1101/2024.07.02.601583 — ecology — Posted on 2024-07-04

4442 Putting the Asymmetric Response Concept to the test: modeling multiple stressor exposure and release in a stream food web

Kuppels, A.; Bayat, H. S.; Gillmann, S. M.; Schaefer, R. B.; Vos, M.

10.1101/2024.07.02.601677 — ecology — Posted on 2024-07-04

4443 Long-lasting negative effects of past forestation on grassland pollination networks and their function

Hirayama, G. S.; Inoue, T.; Hiroshi, I. S.; Kenta, T.; Ushimaru, A.

10.1101/2024.07.02.601666 — ecology — Posted on 2024-07-04

4444 A ready-to use workflow for automated, sound-based bird identification and localization

Buchmann, C. M.; Schurr, F. M.

10.1101/2024.07.02.601711 — ecology — Posted on 2024-07-04

4445 Induction of ectopic external gills and tetrapodomorph-like skeletal elements through homeotic transformations in the salamander branchial region

Vintr, J.; Soukup, V.

10.1101/2024.07.02.601774 — developmental biology — Posted on 2024-07-04

4446 Epigenetic changes regulating the epithelial-mesenchymal transition in human trophoblast differentiation

Ackerman, W. E.; Rigo, M. M.; DaSilva-Arnold, S. C.; Do, C.; Tariq, M.; Salas, M.; Castano, A.; Zamudio, S.; Tycko, B.; Illsley, N. P.

10.1101/2024.07.02.601748 — developmental biology — Posted on 2024-07-04

4447 FABP4-mediated lipid accumulation and lipolysis in tumor associated macrophages promote breast cancer metastasis

Li, B.

10.1101/2024.07.02.601733 — immunology — Posted on 2024-07-04

4448 Lack of Synergistic Outcomes with Roflumilast Combined with Levetiracetam or Adipose Stem Cell Secretome After Spinal Cord Injury

Sousa, C.; lima, R.; Gomes, E. D.; Silva, D.; Cibrao, J.; Pinho, T.; Santos, D.; Afonso, J.; Martins-Macedo, J.; Monteiro, A.; Salgado, A. J.; Silva, N. A.

10.1101/2024.07.02.601664 — neuroscience — Posted on 2024-07-04

4449 Reciprocal interactions between CA1 pyramidal and axo-axonic cells control sharp wave-ripple events

Gilbert, E. T.; Klaver, L. M. F.; Arndt, K. C.; Kim, J.; Jia, X.; McKenzie, S.; English, D. F.

10.1101/2024.07.02.601726 — neuroscience — Posted on 2024-07-04

4450 An Intra-brainstem Circuit for Pain-induced Inhibition of Itch

Prajapati, J. N.; Shah, D. P.; Barik, A.

10.1101/2024.07.02.601724 — neuroscience — Posted on 2024-07-04

4451 Redox signaling by hydrogen peroxide modulates axonal microtubule organization and induces a specific phosphorylation signature of microtubule proteins distinct from distress

Conze, C.; Trushina, N. I.; Monteiro-Abreu, N.; Villar Romero, D.; Wienbeuker, E.; Schwarze, A.-S.; Holtmannspoetter, M.; Bakota, L.; Brandt, R.

10.1101/2024.07.01.601594 — neuroscience — Posted on 2024-07-04

4452 EPILEPTOGENESIS INHIBITS THE CIRCADIAN CLOCK AND RESHAPES THE DIURNAL TRANSCRIPTOMIC RHYTHMICITY IN THE MOUSE HIPPOCAMPUS

Benvenutti, R.; Bruno, D. C. F.; Gallas-Lopes, M.; Veno, M. T.; Bruxel, E. M.; Strickland, T.; Ramsook, A.; Wadgaonkar, A.; Jiang, Y.; Sanz-Rodriguez, A.; Sinkkonen, L.; Alvim, M. K. M.; Yasuda, C. L.; Rogerio, F.; Cendes, F.; Henshall, D. C.; Curtis, A. M.; Kobow, K.; Lopes-Cendes, I.; Reschke, C. R.

10.1101/2024.07.02.601732 — neuroscience — Posted on 2024-07-04

4453 Spectrotemporal profiling of ultrasonic vocalizations during neonatal opioid withdrawal reveals a kappa opioid receptor component in female mice

Wingfield, K. K.; Misic, T.; Jain, K.; McDermott, C. S.; Abney, N. M.; Richardson, K. T.; Rubman, M. B.; Beierle, J. A.; Miracle, S. A.; Sandago, E. J.; Baskin, B. M.; Borrelli, K. N.; Yao, E. J.; Wachman, E. M.; Bryant, C. D.

10.1101/2024.07.02.601766 — neuroscience — Posted on 2024-07-04

4454 IGF-1 Acts through Kiss1-expressing Cells to Influence Metabolism and Reproduction

Wang, M.; Pugh, S. M.; Daboul, J.; Miller, D.; Xu, Y.; Hill, J. W.

10.1101/2024.07.02.601722 — neuroscience — Posted on 2024-07-04

4455 Parallel measurement of transcriptomes and proteomes from same single cells using nanodroplet splitting

Fulcher, J. M.; Markillie, L. M.; Mitchell, H. D.; Williams, S. M.; Engbrecht, K. M.; Degnan, D. J.; Bramer, L.; Moore, R. J.; Chrisler, W. B.; Cantlon-Bruce, J.; Bagnoli, J. W.; Qian, W.; Seth, A.; Pasa-Tolic, L.; Zhu, Y.

10.1101/2022.05.17.492137 — systems biology — Posted on 2024-07-04

4456 Structural insights into the recognition of RALF peptides by FERONIA receptor kinase during Brassicaceae Pollination

Bhalla, H.; Sudarsanam, K.; Srivastava, A.; Sankaranarayanan, S.

10.1101/2024.07.02.601642 — plant biology — Posted on 2024-07-04

4457 Tks5 interactome reveals ER-associated machinery translation in invadosomes.

NORMAND, L.; BONNARD, B.; Sala, M.; DI-TOMMASO, S.; DOURTHE, C.; RAYMOND, A.-A.; DUPUY, J.-W.; MERCIER, L.; GOETZ, J. G.; MOREAU, V.; HENRIET, E.; SALTEL, F.

10.1101/2024.07.02.601728 — cancer biology — Posted on 2024-07-04

4458 Uridine Phosphorylase-1 supports metastasis of mammary cancer by altering immune and extracellular matrix landscapes of the lung

Whyte, D.; Vande Voorde, J.; Sumpton, D.; Dhayade, S.; Dornier, E.; Moore, M.; Novo, D.; Peters, J.; Wiesheu, R.; Mackey, J. B.; McFarlane, A. J.; Fercoq, F.; Fisher, S.; Dehesa Caballero, C.; Gilroy, K.; Redmond, K. L.; Mitchell, L. E.; Anderson, E.; Thomson, G.; Dzierozynski, L. N.; Apiz Saab, J. J.; Lewis, C. A.; Muir, A.; Halbrook, C. J.; Strathdee, D.; Jackstadt, R.; Nixon, C.; Dunne, P.; Steele, C. W.; Carlin, L. M.; Macpherson, I. R.; Roberts, E. W.; Coffelt, S. B.; Blyth, K.; Sansom, O. J.; Norman, J. C.; Clarke, C. J.

10.1101/2024.07.02.601676 — cancer biology — Posted on 2024-07-04

4459 An integrin centered complex coordinates ion transport and pH to regulate f-actin organization and cell migration in breast cancer.

Capitani, C.; Iorio, J.; Lastraioli, E.; Duranti, C.; Bagni, G.; Chioccioli Altadonna, G.; Colasurdo, R.; Scarpellino, G.; Fraser, S. P.; Becchetti, A.; Djamgoz, M. B. A.; Arcangeli, A.

10.1101/2024.07.02.601509 — cancer biology — Posted on 2024-07-04

4460 Deep learning identifies heterogeneous subpopulations in breast cancer cell lines

Jost, T. A.; Gardner, A. L.; Morgan, D.; Brock, A. A.

10.1101/2024.07.02.601576 — cancer biology — Posted on 2024-07-04

4461 Chaotropic Agent-assisted Supported Lipid Bilayer Formation

Cawley, J. L.; Santa, D. E.; Singh, A. N.; Odudimu, A. T.; Berger, B. A.; Wittenberg, N. J.

10.1101/2024.07.02.601713 — biophysics — Posted on 2024-07-04

4462 Physical constraints and biological regulations underlie universal osmoresponses

Ye, Y.; Wang, Q.; Lin, J.

10.1101/2024.07.02.601668 — biophysics — Posted on 2024-07-04

4463 tauX: A Gene Expression Ratio Strategy to Improve Machine Learning Applications in Precision Medicine

Pfeil, J.; Ma, L.; Lo, H. C.; Turan, T.; McLaughlin, R. T.; Shi, X.; Villarruel, S.; Wilson, S.; Zhao, X.; Samayoa, J.; Halliwill, K.

10.1101/2024.07.01.601595 — bioinformatics — Posted on 2024-07-04

4464 Benchmarking Large Language Models for Bio-Image Analysis Code Generation

Haase, R.; Tischer, C.; Heriche, J.-K.; Scherf, N.

10.1101/2024.04.19.590278 — bioinformatics — Posted on 2024-07-04

4465 Intervening to preserve function in ischemic cardiomyopathy with a porous hydrogel and extracellular matrix composite in a rat myocardial infarction model

Hayashi, Y.; Fujii, T.; Kim, S.; Badylak, S. F.; D'Amore, A.; Wagner, W. R.

10.1101/2024.07.02.601690 — bioengineering — Posted on 2024-07-04

4466 Distinct populations suppress or escalate intake of cocaine paired with aversive quinine.

Powers, R. E.; Fogel, P. A.; Reeves, J. H.; Madrid, P.; Moschak, T. M.

10.1101/2024.07.01.601599 — animal behavior and cognition — Posted on 2024-07-04

4467 Intra- and interspecific variations in flight performance of oak-associated Agrilinae (Coleoptera: Buprestidae) using computerised flight mills

Le Souchu, E.; Salle, A.; Bankhead-Dronnet, S.; Laparie, M.; Sauvard, D.

10.1101/2024.07.01.601558 — animal behavior and cognition — Posted on 2024-07-04

4468 Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast

Dennen, M. S.; Kockler, Z. W.; Roberts, S. A.; Burkholder, A. B.; Klimczak, L. J.; Gordenin, D. A.

10.1101/2024.06.27.601081 — genetics — Posted on 2024-07-04

4469 Reproductive output of old polygynous males is limited by seminal fluid, not sperm number

Sanghvi, K.; Shandilya, S.; Brown, A.; Todorova, B.; Jahn, M.; Gascoigne, S.; Camilleri, T.-L.; Pizzari, T.; Sepil, I.

10.1101/2024.07.02.601670 — evolutionary biology — Posted on 2024-07-04

4470 Ecology not genetics explains correlated trait divergence during speciation

de Carvalho, C.; Planidin, N.; Villoutreix, R.; Soria-Carrasco, V.; Riesch, R.; Feder, J.; Parchman, T.; Slate, J.; Gompert, Z.; Nosil, P.

10.1101/2024.07.02.601691 — evolutionary biology — Posted on 2024-07-04

4471 Large shifts in diatom and dinoflagellate biomass in the North Atlantic over six decades

Mutshinda, C.; Finkel, Z. V.; Irwin, A. J.

10.1101/2024.07.02.601152 — ecology — Posted on 2024-07-04

4472 Innovative Use of Depth Data to Estimate Energy Intake and Expenditure in Adelie Penguins

Dupuis, B.; Kato, A.; Hicks, O.; Wisniewska, D. M.; Marciau, C.; Angelier, F.; Ropert-Coudert, Y.; Chimienti, M.

10.1101/2024.07.02.601650 — ecology — Posted on 2024-07-04

4473 A genome engineered tool set for Drosophila TGF-β/BMP signaling studies

Ell, C.-M.; Safyan, A.; Chayengia, M.; Kustermann, M. M. M.; Lorenz, J.; Schächtle, M.; Pyrowolakis, G.

10.1101/2024.07.02.601693 — developmental biology — Posted on 2024-07-04

4474 The CCT chaperonin and actin modulate the ER and RNA-binding protein condensation during oogenesis to maintain translational repression of maternal mRNA and oocyte quality

Elaswad, M. T.; Gao, M.; Tice, V. E.; Bright, C. G.; Thomas, G. M.; Munderloh, C.; Trombley, N. J.; Haddad, C. N.; Johnson, U. G.; Cichon, A. N.; Schisa, J. A.

10.1101/2024.07.01.601596 — developmental biology — Posted on 2024-07-04

4475 EFL-3/E2F7 modulates Wnt signalling through repressing the LIT-1 Nemo-like kinase during asymmetric epidermal cell division in Caenorhabditis elegans

Ferrando-Marco, M.; Barkoulas, M.

10.1101/2024.07.01.601538 — developmental biology — Posted on 2024-07-04

4476 Basophils drive the resolution and promote wound healing in adult and aged mice

Bex, J.; Peter, V.; Saji, C.; Chapart, L.; Jin, S.; Gauthier, G.; Thibaudeau, O.; Thaminy, M. K.; Tchen, J.; Simon, Q.; Dai, X.; Miyake, K.; Karasuyama, H.; Jiang, J. X.; Naidoo, K.; Benhamou, M.; Blank, U.; Monteiro, R.; Le Gros, G.; Charles, N.; Pellefigues, C.

10.1101/2024.07.02.601665 — immunology — Posted on 2024-07-04

4477 A VgrG2b fragment cleaved by caspase-11/4 promotes Pseudomonas aeruginosa infection through suppressing the NLRP3 inflammasome

Qian, Y.; Liu, Q.; Li, W.; Wang, C.; Kong, C.; Li, M.; Wang, S.; Xia, P.

10.1101/2024.07.02.601667 — immunology — Posted on 2024-07-04

4478 Poly(allylamine)-tripolyphosphate polymeric nanoparticle as an NLRP3-dependent systemic adjuvant for the vaccine development

Rizzo, G. P.; Sanches, R. C.; Chavero, C.; Bianchi, D. S.; Apuzzo, E.; Herrera, S. E.; Agazzi, M. L.; Keitelman, I. A.; Trevani, A. S.; Oliveira, S. C.; Azzaroni, O.; Smaldini, P. L.; Docena, G. H.

10.1101/2024.07.01.601578 — immunology — Posted on 2024-07-04

4479 Adult-neurogenesis allows for representational stability and flexibility in early olfactory system

Chen, Z.; Padmanabhan, K.

10.1101/2024.07.02.601573 — neuroscience — Posted on 2024-07-04

4480 Dynamic functional connectivity correlates of trait mindfulness in early adolescence

Treves, I. N.; Marusak, H. A.; Decker, A.; Kucyi, A.; Hubbard, N. A.; Bauer, C. C. C.; Leonard, J.; Grotzinger, H.; Giebler, M. A.; Camacho Torres, Y.; Imhof, A.; Romeo, R.; Calhoun, V.; Gabrieli, J. D. E.

10.1101/2024.07.01.601544 — neuroscience — Posted on 2024-07-04

4481 Building a small brain with a simple stochastic generative model

Richter, O.; Schneidman, E.

10.1101/2024.07.01.601562 — neuroscience — Posted on 2024-07-04

4482 Gene expression asymmetry in Parkinson's Disease; variation of CCT and BEX gene expression levels are correlated with hemisphere specific severity

Pierce, S. E.; van der Schans, E. J. C.; Ensink, E.; Coetzee, G. A.

10.1101/2024.07.02.601704 — neuroscience — Posted on 2024-07-04

4483 iTome Volumetric Serial Sectioning Apparatus for TEM

Peale, D. R.; Hess, H.; Lee, P. R.; Cardona, A.; Bock, D.; Schneider-Mizell, C. M.; Fetter, R. D.; Lee, W.-P.; Robinson, C. G.; Iyer, N.; Managan, C.

10.1101/2024.07.02.601671 — neuroscience — Posted on 2024-07-04

4484 Microglia-astrocyte interplay mitigates Aβ toxicity in a novel human 3D neurosphere model of Alzheimer's Disease

Wendt, S.; Lin, A. J.; Ebert, S. N.; Brennan, D. J.; Cai, W.; Bai, Y.; Sorrentino, S.; Groten, C. J.; Lee, C.; Frew, J.; Choi, H. B.; Karamboulas, K.; Delhaye, M.; Kaplan, D. R.; Miller, F.; MacVicar, B. A.; Nygaard, H. B.

10.1101/2024.07.01.601570 — neuroscience — Posted on 2024-07-04

4485 Rhythmic modulation of subthalamo-pallidal interactions depends on synaptic rewiring through inhibitory plasticity

Madadi Asl, M.; Lea-Carnall, C. A.

10.1101/2024.07.01.601477 — neuroscience — Posted on 2024-07-04

4486 Sleep homeostasis in a naturalistic setting

Ujma, P. P.; Bodizs, R.

10.1101/2024.07.02.601682 — neuroscience — Posted on 2024-07-04

4487 Mapping the Learning Curves of Deep Learning Networks

Jiang, Y.; Dale, R.

10.1101/2024.07.01.601491 — scientific communication and education — Posted on 2024-07-04

4488 Exploring Comorbidity Networks in Mild Traumatic Brain Injury Subjects through Graph Theory: A Traumatic Brain Injury Model Systems Study

Mehta, K.; Sudhakar, S. K.

10.1101/2024.07.02.601618 — neuroscience — Posted on 2024-07-04

4489 Upregulated expression of ubiquitin ligase TRIM21 promotes PKM2 nuclear translocation and astrocyte activation in experimental autoimmune encephalomyelitis

Yang, L.; Hu, C.; Chen, X.; Zhang, J.; Feng, Z.; Xiao, Y.; He, W.; Cui, T.; Zhang, X.; Yang, Y.; Zhang, Y.; Yan, Y.

10.1101/2024.04.22.590550 — neuroscience — Posted on 2024-07-04

4490 Load-dependent and load-independent effects on longitudinal motor training in human continuous hand movements

Wang, X.; Liang, X.; Ku, Y.; Zhan, Y.; Song, R.

10.1101/2024.07.01.601475 — neuroscience — Posted on 2024-07-04

4491 Epilepsy protein myoclonin1 interacts with inositol 1,4,5-trisphosphate (IP3) receptor and reduces Ca2+ store in endoplasmic reticulum

Suzuki, T.; Aguan, K.; Mizuno, H.; Nakamura, T.; Inoue, I.; Mikoshiba, K.; Miyawaki, A.; Yamakawa, K.

10.1101/2024.07.01.601633 — physiology — Posted on 2024-07-04

4492 Effect of zinc supplementation on certain serum biochemical parameters in growing pigs

Borah, S.; Soren, S.; Deka, S. S.; Kalita, L.; Pame, K.; Borah, B.

10.1101/2024.07.02.601647 — physiology — Posted on 2024-07-04

4493 Leveraging machine learning to streamline the development of liposomal drug delivery systems

Eugster, R.; Orsi, M.; Buttitta, G.; Serafini, N.; Tiboni, M.; Casettari, L.; Reymond, J.-L.; Aleandri, S.; Luciani, P.

10.1101/2024.07.01.600773 — pharmacology and toxicology — Posted on 2024-07-04

4494 Exenatide administration time determines the effects on blood pressure dipping in db/db mice via modulation of food intake and sympathetic activity

Chacon, A. N.; Su, W.; Hou, T.; Guo, Z.; Gong, M. C.

10.1101/2024.07.02.601700 — pharmacology and toxicology — Posted on 2024-07-04

4495 The metabolic benefits of thermogenic stimulation are preserved in aging

Natarajan, D.; Plakkot, B.; Tiwari, K.; Ekambaram, S.; Wang, W.; Rudolph, M.; Mohammad, M.; Chacko, S.; Subramanian, M.; Tarantini, S.; Yabluchanskiy, A.; Ungvari, Z.; Csiszar, A.; Balasubramanian, P.

10.1101/2024.07.01.601572 — pharmacology and toxicology — Posted on 2024-07-04

4496 Tumor- and immune-derived N-acetyl-β-D-hexosaminidase drive colorectal cancer and stratify patient risk

Kawahara, R.; Kautto, L.; Bansal, N.; Dipta, P.; Chau, T. H.; Liquet-Weiland, B.; Ahn, S. B.; Thaysen-Andersen, M.

10.1101/2024.07.02.601644 — cancer biology — Posted on 2024-07-04

4497 Structure of a novel α-synuclein filament fold from multiple system atrophy

Yan, N. L.; Candido, F.; Tse, E.; Melo, A. A.; Prusiner, S. B.; Mordes, D. A.; Southworth, D. R.; Paras, N. A.; Merz, G. E.

10.1101/2024.07.01.601365 — biophysics — Posted on 2024-07-04

4498 Poly(ADP-ribose) binding sites on collagen I fibrils for nucleating intrafibrillar bone mineral

Zecca, M. A.; Greer, H. F.; Duer, M. J.

10.1101/2024.07.02.600619 — biophysics — Posted on 2024-07-04

4499 Replacing non-biomedical concepts improves embedding of biomedical concepts

Niyonkuru, E.; Soto Gomez, M.; Casiraghi, E.; Antogiovanni, S.; Blau, H.; Reese, J. T.; Valentini, G.; Robinson, P. N.

10.1101/2024.07.01.601556 — bioinformatics — Posted on 2024-07-04

4500 Designer DNA nanocages modulate anti-oxidative and anti-inflammatory responses in tumor associated macrophages

Vaswani, P.; Bhatia, D. D.

10.1101/2024.07.01.601504 — bioengineering — Posted on 2024-07-04

4501 Capturing gait parameters during asymmetric overground walking using ultra-wideband radars: A preliminary study

Hadjipanayi, C.; Yin, M.; Constandinou, T.

10.1101/2024.07.01.601550 — bioengineering — Posted on 2024-07-04

4502 Disease exacerbation in MYOrganoids derived from Duchenne Muscular Dystrophy iPSC reveals limitations of microdystrophin therapeutic efficacy

Palmieri, L.; Pili, L.; Jaber, A.; Vu Hong, A.; Moula, M.; El Khoury, R.; Brochiet, G.; Bigot, A.; Israeli, D.; Richard, I.; Albini, S.

10.1101/2023.07.26.550063 — bioengineering — Posted on 2024-07-04

4503 Corneal keratocytes, fibroblasts, and myofibroblasts exhibit distinct transcriptional profiles in vitro

Poole, K.; Iyer, K. S.; Schmidtke, D. W.; Petroll, M.; Varner, V. D.

10.1101/2024.02.28.582620 — bioengineering — Posted on 2024-07-04

4504 Transposable element expression with variation in sex chromosome number: insights into a toxic Y effect on human longevity

10.1101/2023.08.03.550779 — genomics — Posted on 2024-07-04

4505 Clockwork Orangutan: microRNAs, thermoregulatory tradeoffs, and the evolution of brain size.

Fromm, B.; Sorger, T.

10.1101/2024.05.21.595052 — evolutionary biology — Posted on 2024-07-04

4506 Chitosan reduces naturally occurring plant pathogenic fungi and increases nematophagous fungus Purpureocillium in field soil

Lopez-Nunez, R.; Prieto-Rubio, J.; Bautista-Carrascosa, I.; Lidon-Cerezuela, A. L.; Lopez-Moya, F.; Lopez-Llorca, L. V.

10.1101/2024.07.01.600678 — ecology — Posted on 2024-07-04

4507 Floral visitors differentially respond to local and landscape grassland features

Lichtenberg, E. M.; Heiser, J.; Baum, K. A.; Neff, J. L.; Jha, S.

10.1101/2024.07.01.601588 — ecology — Posted on 2024-07-04

4508 Comparative analysis of the syncytiotrophoblast in placenta tissue and trophoblast organoids using snRNA sequencing

Keenen, M. M.; Yang, L.; Liang, H.; Farmer, V. J.; Singh, R.; Gladfelter, A. S.; Coyne, C. B.

10.1101/2024.07.01.601571 — developmental biology — Posted on 2024-07-04

4509 Unravelling a diversity of cellular structures and aggregation dynamics during the early development of Myxococcus xanthus

Rivera-Yoshida, N.; Arzola, A. V.; Benitez, M.

10.1101/2024.07.01.601548 — developmental biology — Posted on 2024-07-04

4510 Borg3 controls septin recruitment for primary cilia formation

Schampera, J. N.; Lehmann, F.; Melendez, A. V.; Schwan, C.

10.1101/2024.06.04.597321 — cell biology — Posted on 2024-07-04

4511 Parallel Synapses with Transmission Nonlinearities Enhance Neuronal Classification Capacity

Song, Y.; Benna, M. K.

10.1101/2024.07.01.601490 — neuroscience — Posted on 2024-07-04

4512 Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

Ifejeokwu, O. V.; Do, A. H.; El-Khatib, S. M.; Ho, N. H.; Zavala, A.; Othy, S.; Acharya, M. M.

10.1101/2024.07.01.601087 — neuroscience — Posted on 2024-07-04

4513 Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain

Zhang, C.; Huang, Q.; Ford, N. C.; Limjunyawong, N.; Lin, Q.; Yang, F.; Cui, X.; Uniyal, A.; Liu, J.; Mahabole, M.; He, H.; Wang, X.; Duff, I.; Wang, Y.; Wan, J.; Zhu, G.; Raja, S. N.; Jia, H.; Yang, D.; Dong, X.; Cao, X.; Tseng, S.; He, S.; Guan, Y.

10.1101/2024.05.19.594874 — neuroscience — Posted on 2024-07-04

4514 The relationship between microbial community succession, decay, and anatomical character loss in non-biomineralised animals

Clements, T.; Goodall, R.; Gabbott, S.; Murdock, D.; Clokie, M.; Millard, A.; Turkington, C.; Bath-Enright, O.; Purnell, M. A.

10.1101/2024.07.01.601543 — paleontology — Posted on 2024-07-04

4515 Triphasic Thrombosis Model: A Computational Study of Type B Aortic Dissection

Gupta, I.; Schanz, M.; Ricken, T.

10.1101/2024.05.07.592918 — biophysics — Posted on 2024-07-04

4516 High-speed 3D DNA PAINT and unsupervised clustering for unlocking 3D DNA origami cryptography

Wisna, G. B. M.; Sukhareva, D.; Zhao, J.; Satyabola, D.; Matthies, M.; Roy, S.; Wang, C.; Sulc, P.; Yan, H.; Hariadi, R. F.

10.1101/2023.08.29.555281 — biophysics — Posted on 2024-07-04

4517 The Asgard archaeal ESCRT-III system forms helical filaments and remodels eukaryotic membranes, shedding light on the emergence of eukaryogenesis

Melnikov, N.; Junglas, B.; Halbi, G.; Nachmias, D.; Zerbib, E.; Upcher, A.; Zalk, R.; Sachse, C.; Bernheim, A.; Elia, N.

10.1101/2022.09.07.506706 — biochemistry — Posted on 2024-07-04

4518 T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses

Billaud, M.; Theodorou, I.; Lamy-Besnier, Q.; Shah, S. A.; Lecointe, F.; De Sordi, L.; De Paepe, M.; Petit, M.-A.

10.1101/2022.12.12.520144 — genomics — Posted on 2024-07-04

4519 Chronospaces: an R package for the statistical exploration of divergence times promotes the assessment of methodological sensitivity

Mongiardino Koch, N.; Milla Carmona, P.

10.1101/2024.02.04.578835 — evolutionary biology — Posted on 2024-07-04

4520 Deep sequencing of 16 Ixodes ricinus ticks unveils insights into their interactions with endosymbionts

Lesiczka, P. M.; Azagi, T.; Krawczyk, A. I.; Scott, W. T.; Dirks, R. P.; Simo, L.; Dobler, G.; Nijsse, B.; Schaap, P. J.; Sprong, H.; Koehorst, J. J.

10.1101/2024.04.22.590557 — microbiology — Posted on 2024-07-04

4521 Phageome transfer from gut to circulation and its regulation by human immunity

Szymczak, A.; Gembara, K.; Ferenc, S.; Majewska, J.; Miernikiewicz, P.; Harhala, M.; Rybicka, I.; Strapagiel, D.; Slomka, M.; Lach, J.; Gnus, J.; Staczek, P.; Witkiewicz, W.; Dabrowska, K.

10.1101/2024.06.05.597592 — microbiology — Posted on 2024-07-04

4522 Peculiar transcriptional reprogramming with functional impairment of dendritic cells upon exposure to transformed HTLV-1-infected cells

Carcone, A.; Mortreux, F.; Alais, S.; Mathieu, C.; Journo, C.; DUTARTRE, H.

10.1101/2024.05.21.592359 — microbiology — Posted on 2024-07-04

4523 Metabolic Dependency Shapes Bivalent Antiviral Response in Host Cells in response to poly:IC: The Role of Glutamine

Lebeau, G.; Paulo-Ramos, A.; Hoareau, M.; El Safadi, D.; Meilhac, O.; Krejbich-Trotot, P.; Roche, M.; Viranaicken, W.

10.1101/2023.08.31.555729 — immunology — Posted on 2024-07-04

4524 Comparative neuroimaging of the carnivoran brain: Neocortical sulcal anatomy

Boch, M.; Karadachka, K.; Loh, K. K.; Benn, R. A.; Roumazeilles, L.; Bertelsen, M. F.; Manger, P. R.; Wriggelsworth, E.; Spiro, S.; Spocter, M. A.; Johnson, P. J.; Avelino-de-Souza, K.; Patzke, N.; Lamm, C.; Miller, K. L.; Sallet, J.; Khrapitchev, A. A.; Tendler, B. C.; Mars, R. B.

10.1101/2024.06.03.597118 — neuroscience — Posted on 2024-07-04

4525 Visuomotor association orthogonalizes visual cortical population codes

Failor, S. W.; Carandini, M.; Harris, K. D.

10.1101/2021.05.23.445338 — neuroscience — Posted on 2024-07-04

4526 Functional Implications of the Exon 9 Splice Insert in GluK1 Kainate Receptors

Dhingra, S.; Chopade, P. M.; Vinnakota, R.; Kumar, J.

10.1101/2023.06.20.545708 — neuroscience — Posted on 2024-07-04

4527 Control of innate olfactory valence by segregated cortical amygdala circuits

Howe, J. R.; Chan, C.-L.; Lee, D.; Blanquart, M.; Romero, H.; Zadina, A. N.; Lemieux, M. E.; Desplats, P. A.; Tye, K. M.; Root, C. M.

10.1101/2024.06.26.600895 — neuroscience — Posted on 2024-07-04

4528 Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles

Lee, S. S.; Civitelli, L.; Parkkinen, L.

10.1101/2023.10.04.560803 — neuroscience — Posted on 2024-07-04

4529 Antibody-based immunotherapy targeting FAM19A5 reverses synaptic loss and improves cognitive function in Alzheimer's disease.

Seong, J. Y.; Kim, H.-B.; Yoo, S.; Kwak, H.; Ma, S.-X.; Kim, R.; Lee, M.; Ha, N.; Pyo, S.; Kwon, S.-G.; Cho, E.-H.; Lee, S.-M.; Jang, J.; Kim, W.; Park, H.-C.; Baek, M.; Park, Y.; Park, J.-Y.; Park, J.-W.; Hwang, S. W.; Hwang, J.-I.

10.1101/2023.11.22.568357 — neuroscience — Posted on 2024-07-04

4530 Trazodone, dibenzoylmethane and tauroursodeoxycholic acid do not prevent motor dysfunction and neurodegeneration in Marinesco-Sjögren syndrome mice

Lavigna, G.; Grasso, A.; Pasini, C.; Grande, V.; Mignogna, L.; Restelli, E.; Masone, A.; Fracasso, C.; Lucchetti, J.; Gobbi, M.; Chiesa, R.

10.1101/2024.04.30.591862 — pharmacology and toxicology — Posted on 2024-07-04

4531 Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

Jepsen, V. H.; Hanel, A.; Picard, D.; Mehtonen, J.; Hasselmann, R.; Schliehe-Diecks, J.; Scharov, K.; Tu, J.-W.; Bhave, R.; Kameri, E.; Qin, N.; Wang, H.; Zhuang, Z.; Wagener, R.; Blümel, L.; Lautwein, T.; Hein, D.; Kögler, G.; Remke, M.; Bhatia, S.; Heinäniemi, M.; Borkhardt, A.; Fischer, U.

10.1101/2024.06.28.601221 — cancer biology — Posted on 2024-07-04

4532 Structural visualisation of the dynamics of DNA unwinding by a replicative helicase

Shahid, T.; Tehseen, M.; Alhudhali, L.; Clark, A. R.; Savva, C. G.; Hamdan, S. M.; De Biasio, A.

10.1101/2024.04.19.590217 — biophysics — Posted on 2024-07-04

4533 Sterol-lipids enable large-scale, liquid-liquid phase separation in bilayer membranes of only 2 components

Wilson, K. J.; Nguyen, H. Q.; Gervay-Hague, J.; Keller, S. L.

10.1101/2024.02.02.578692 — biophysics — Posted on 2024-07-04

4534 Accelerated dimensionality reduction of single -cell RNA sequencing data with fastglmpca

Weine, E.; Carbonetto, P.; Stephens, M.

10.1101/2024.03.23.586420 — bioinformatics — Posted on 2024-07-04

4535 Castanet: a pipeline for rapid analysis of targeted multi-pathogen genomic data

Mayne, R. M.; Secret, S.; Geoghegan, C.; Trebes, A.; Kean, K.; Reid, K.; Lin, G.-L.; Ansari, M. A.; de Cesare, M.; Bonsall, D.; Elliott, I.; Piazza, P.; Brown, A.; Bray, J.; Knight, J. C.; Harvala, H.; Breuer, J.; Simmonds, P.; Bowden, R. J.; Golubchik, T.

10.1101/2024.06.28.601013 — bioinformatics — Posted on 2024-07-04

4536 PENGUIN: A rapid and efficient image preprocessing tool for multiplexed spatial proteomics

Sequeira, A. M.; Ijsselsteijn, M. E.; Rocha, M.; de Miranda, N. F. C. C.

10.1101/2024.07.01.601513 — bioinformatics — Posted on 2024-07-04

4537 Zinc stimulation of phytoplankton in a low carbon dioxide, coastal Antarctic environment

Kell, R. M.; Subhas, A. V.; Schanke, N. L.; Lees, L. E.; Chmiel, R. J.; Rao, D.; Brisbin, M. M. M.; Moran, D. M.; McIlvin, M. R.; Bolinesi, F.; Mangoni, O.; Casotti, R.; Balestra, C.; Horner, T.; Dunbar, R. B.; Allen, A. E.; DiTullio, G. R.; Saito, M. A.

10.1101/2023.11.05.565706 — biochemistry — Posted on 2024-07-04

4538 Altered spawning seasons of Atlantic salmon broodstock genetically and epigenetically influence cell cycle and lipid-mediated regulations in their offspring

Saito, T.; Espe, M.; Mommens, M.; Bock, C.; Fernandes, J. M. O.; Skjaerven, K. H.

10.1101/2024.02.03.578741 — genomics — Posted on 2024-07-04

4539 Diet drives performance trade-offs along Atlantic salmon ontology

Aykanat, T.; Jacobsen, J. A.; Hindar, K.

10.1101/2024.06.04.597289 — ecology — Posted on 2024-07-04

4540 A noncanonical GTPase signaling mechanism controls exit from mitosis in budding yeast

Zhou, X.; Weng, S. Y.; Bell, S. P.; Amon, A.

10.1101/2024.05.16.594582 — cell biology — Posted on 2024-07-04

4541 Balancing safety and efficiency in human decision making

Mahajan, P.; Tong, S.; Lee, S. W.; Seymour, B.

10.1101/2024.01.23.576678 — neuroscience — Posted on 2024-07-04

4542 Gossamer: Scaling Image Processing and Reconstruction to Whole Brains

Marrett, K.; Moradi, K.; Park, C. S.; Yan, M.; Choi, C.; Zhu, M.; Akram, M.; Nanda, S.; Xue, Q.; Mun, H.-S.; Gutierrez, A. E.; Rudd, M.; Zingg, B.; Magat, G.; Wijaya, K.; Dong, H.; Yang, X. W.; Cong, J.

10.1101/2024.04.07.588466 — neuroscience — Posted on 2024-07-04

4543 Identification and validation of reference genes for RT-qPCR single-gene relative expression analysis in Taenia solium pre-adult stages

Castaneda, D.; Maravi, J. d. C.; Gutierrez-Loli, R.; Villar, V.; Blume La Torre, J.; Del Aguila, S. W.; Guerra-Giraldez, C.

10.1101/2022.03.22.485324 — microbiology — Posted on 2024-07-04

4544 Modular organization of synapses within a neuromere for distinct axial locomotion in Drosophila larvae

Fukumasu, K.; Nose, A.; Kohsaka, H.

10.1101/2024.06.29.601329 — neuroscience — Posted on 2024-07-04

4545 Replay in human visual cortex is linked to the formation of successor representations and independent of consciousness

Wittkuhn, L.; Krippner, L. M.; Koch, C.; Schuck, N. W.

10.1101/2022.02.02.478787 — neuroscience — Posted on 2024-07-04

4546 Physiological Harmony or Discord? Unveiling the Correspondence Between Subjective Arousal, Valence and Physiological Responses

Koppold, A.; Lonsdorf, T. B.; Kuhn, M.; Weymar, M.; Ventura-Bort, C.

10.1101/2024.05.31.596899 — neuroscience — Posted on 2024-07-04

4547 The "motive cocktail" in altruistic behaviors

Wu, X.; Ren, X.; Liu, C.; Zhang, H.

10.1101/2023.08.20.554026 — neuroscience — Posted on 2024-07-04

4548 SCIP: a self-paced, community-based summer coding program creates community and increases coding confidence, lessons learned from the pandemic

Reyes, R.-J.; Pham, O.; Fergusson, R.; Ceberio, N.; Clark, C.; Cohen, C. S.; Fuse, M.; Pennings, P. S.

10.1101/2022.12.27.521952 — scientific communication and education — Posted on 2024-07-04

4549 Ancestral SARS-CoV-2 immune imprinting persists on RBD but not NTD after sequential Omicron infections

Wang, Z.; Li, L.; Du, R.; Chen, X.; Sun, Y.; Qin, R.; Li, Y.; Feng, H.; Hu, L.; Chen, X.; Lu, M.; Jiang, L.; Zuo, T.

10.1101/2024.05.30.596664 — immunology — Posted on 2024-07-04

4550 Joint modelling of whole genome sequence data for human height via approximate message passing

Depope, A.; Bajzik, J.; Mondelli, M.; Robinson, M. R.

10.1101/2023.09.14.557703 — genetics — Posted on 2024-07-04

4551 The DNA Replication Checkpoint Targets the Kinetochore for Relocation of Collapsed Forks to the Nuclear Periphery

Maclay, T. M.; Whalen, J.; Johnson, M.; Freudenreich, C. H.

10.1101/2024.06.17.599319 — cell biology — Posted on 2024-07-04

4552 Hypoxia-Inducible Factor-1 activated by PIM1 assembles a non-canonical transcription complex and resultant regulon that drives progression of JAK2V617F myeloproliferative neoplasms

Kealy, D.; Ellerington, R.; Bansal, S.; Zeng, A. G. X.; Medeiros, J. J. F.; West, K. A.; Blacknell, N.-M.; Hawley, C. A.; Lukaszonek, J.; Gawne, R.; Khoo, H. M.; Caalim, G.; Drylie, B.; Chatzigerou, J.; Rodriguez Lima Ferreira, B.; Wang, G.; Fielding, A. K.; Kent, D.; Psaila, B.; Wilkinson, A. C.; Holding, A. N.; Hitchcock, I. S.; Mason, A. S.; Gupta, V.; Dick, J.; Bridge, K. S.

10.1101/2024.07.02.601518 — cancer biology — Posted on 2024-07-04

4553 Transcriptome-wide characterization of genetic perturbations

Nadig, A.; Replogle, J. M.; Pogson, A. N.; McCarroll, S. A.; Weissman, J. S.; Robinson, E. B.; O'Connor, L. J.

10.1101/2024.07.03.601903 — genomics — Posted on 2024-07-03

4554 DNA Methylation of CpG in the Promoter Regions of HIV Coreceptors Related Genes (CCR5 and CXCR4): Original Research

Esman, A.; Salamaikina, S.; Vinokurov, M.; Fomina, D.; Kirichenko, A.; Pokrovskaya, A.; Akimkin, V.

10.1101/2024.07.01.601546 — genetics — Posted on 2024-07-03

4555 Comparative Genomic Analysis of Metal-Tolerant Bacteria Reveals Significant Differences in Metal Adaptation Strategies

Environment and Healthcare Biotechnology, ; Wu, J. C.

10.1101/2024.07.03.601927 — microbiology — Posted on 2024-07-03

4556 Effects of temperature and salinity on microbial degradation of bacterial necromass in urban river sediments in outdoor mesocosm experiments

Hadziomerovic, U.; Baikova, D.; Madge Pimentel, I.; Buchner, D.; Vermiert, A.-M.; Rehsen, P. M.; Brauer, V. S.; Meckenstock, R. U.

10.1101/2024.07.03.601918 — microbiology — Posted on 2024-07-03

4557 Regulation of proteostasis by sleep through autophagy in Drosophila models of Alzheimer's Disease

Ortiz-Vega, N.; Lobato, A. G.; Canic, T.; Zhu, Y.; Lazopulo, S.; Syed, S.; Zhai, R. G.

10.1101/2024.07.01.601554 — neuroscience — Posted on 2024-07-03

4558 Vasopressin-to-Oxytocin Receptor Crosstalk in the Preoptic Area Underlying Parental Behaviors in Male Mice

Inada, K.; Hagihara, M.; Yaguchi, K.; Irie, S.; Inoue, Y. U.; Inoue, T.; Miyamichi, K.

10.1101/2024.07.01.601605 — neuroscience — Posted on 2024-07-03

4559 Thalamic Control Over Laminar Cortical Dynamics Across Conscious States

Muller, E. J.; Munn, B.; Baracchini, G.; Fulcher, B. D.; Medel, V.; Redinbaugh, M. J.; Saalmann, Y. B.; Brunton, B. W.; Brunton, S. L.; Shine, J.

10.1101/2024.07.02.601788 — neuroscience — Posted on 2024-07-03

4560 Medial prefrontal cortex and nucleus reuniens are critical for working memory in an operant delayed nonmatch task

Ciacciarelli, E. J.; Dunn, S. D.; Gohar, T.; Sloand, T. J.; Niedringhaus, M.; West, E. A.

10.1101/2024.07.03.601891 — neuroscience — Posted on 2024-07-03

4561 Modelling determinants of region-specific dopamine dynamics in the striatum

Ejdrup, A. L.; Dreyer, J. K.; Lycas, M. D.; Jorgensen, S. H.; Robbins, T. W.; Dalley, J. W.; Herborg, F.; Gether, U.

10.1101/2024.07.03.601861 — neuroscience — Posted on 2024-07-03

4562 Familiarity of an environment prevents song suppression in isolated zebra finches

Zai, A. T.; Rodrigues, D. I.; Stepien, A. E.; Adam, I.; Lorenz, C.; Giret, N.; Hahnloser, R. H. R.

10.1101/2024.07.02.601800 — zoology — Posted on 2024-07-03

4563 A flexible framework for minimal biomarker signature discovery from clinical omics studies without library size normalisation

Rawlinson, D. P.; Zhou, C. P.; Le Cao, K.-A.; Coin, L. J. M.

10.1101/2024.07.03.601811 — bioinformatics — Posted on 2024-07-03

4564 Induction of intercrypt goblet cells upon bacterial infection

LEONARD, R.; PASQUEREAU KOTULA, E.; MADEC, E.; MARSAC, B.; MIHALACHE, A.; DU MERLE, L.; DENIS, J.; SPRIET, C.; SANSONETTI, P. J.; DRAMSI, S.; ROBBE MASSELOT, C.

10.1101/2024.07.03.601821 — biochemistry — Posted on 2024-07-03

4565 The Kinetics of Carbon-Carbon-Bond Formation in Metazoan Fatty Acid Synthase and its Impact on Product Fidelity

Gusenda, C.; Calixto, A. R.; da Silva, J. M. R.; Fernandes, P. A.; Grininger, M.

10.1101/2024.07.03.601458 — biochemistry — Posted on 2024-07-03

4566 Structural basis of the human transcriptional Mediator complex modulated by its dissociable Kinase module

Chen, S.-F.; Chao, T.-C.; Kim, H. J.; Tang, H.-C.; Khadka, S.; Li, T.; Lee, D.-F.; Murakami, K.; Boyer, T. G.; Tsai, K.-L.

10.1101/2024.07.01.601608 — biochemistry — Posted on 2024-07-03

4567 Multi-dimensional demarcation of phylogenetic groups of plant 14-3-3 isoforms using biochemical signatures

Sedlov, I. A.; Sluchanko, N. N.

10.1101/2024.07.02.601760 — biochemistry — Posted on 2024-07-03

4568 Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast

Morgan, B.; Zimmermann, J.; Lang, L.; Calabrese, G.; Laporte, H.; Amponsah, P.; Michalk, C.; Sukmann, T.; Oestreicher, J.; Tursch, A.; Peker, E.; Owusu, T.; Weith, M.; Prates Roma, L.; Deponte, M. q.; Riemer, J.

10.1101/2024.07.03.601836 — biochemistry — Posted on 2024-07-03

4569 Promoted Read-through and Mutation Against Pseudouridine-CMC by an Evolved Reverse Transcriptase

Zhou, H.; He, Z.; Qiu, W.

10.1101/2024.07.03.601893 — biochemistry — Posted on 2024-07-03

4570 Fine-tuning of a CRISPRi screen in the seventh pandemic Vibrio cholerae

Debatisse, K.; Niault, T.; Peeters, S.; Maire, A.; Darracq, B.; Baharoglu, Z.; Bikard, D.; Mazel, D.; Loot, C.

10.1101/2024.07.03.601881 — genetics — Posted on 2024-07-03

4571 Benchmarking for genotyping and imputation using degraded DNA for forensic applications across diverse populations

Zavala, E. I.; Rohlfs, R. V.; Moorjani, P.

10.1101/2024.07.02.601808 — genetics — Posted on 2024-07-03

4572 Sedentary chromosomal integrons as biobanks of bacterial anti-phage defence systems

Darracq, B.; Littner, E.; Brunie, M.; Bos, J.; Kaminski, P. A.; Depardieu, F.; Slesak, W.; Debatisse, K.; Touchon, M.; Bernheim, A.; Bikard, D.; Le Roux, F.; Mazel, D.; Rocha, E. P.; Loot, C.

10.1101/2024.07.02.601686 — genetics — Posted on 2024-07-03

4573 Phenotypically wild barley shows evidence of introgression from cultivated barley

Liu, C.; Lei, L.; Shao, M.; Franckowiak, J. D.; Pacheco, J. B.; Scott, J. C.; Gavin, R. T.; Roy, J. K.; Sallam, A. H.; Steffenson, B. J.; Morrell, P. L.

10.1101/2024.07.01.601622 — evolutionary biology — Posted on 2024-07-03

4574 Cancer-associated snaR-A noncoding RNA interacts with core splicing machinery and disrupts processing of mRNA subpopulations

Zhou, S.; Lizarazo, S.; Mouli, L.; Chorghade, S.; Cheng, R.; K C, R.; Kalsotra, A.; Van Bortle, K.

10.1101/2024.07.02.601767 — molecular biology — Posted on 2024-07-03

4575 NPM1 mediates genome-nucleolus interactions and the establishment of their repressive chromatin states

Gupta, S.; Bersaglieri, C.; Baer, D.; Raingeval, M.; Schaab, L.; Santoro, R.

10.1101/2024.07.03.601885 — molecular biology — Posted on 2024-07-03

4576 Wetland tree barks are dynamic hotspots for microbial trace gas cycling

Leung, P. M.; Jeffrey, L. C.; Bay, S. K.; Gomez-Alvarez, P.; Hall, M.; Johnston, S. G.; Dittmann, J.; Jirapanjawat, T.; Hutchinson, T. F.; Coleman, N. V.; Dong, X.; Deschaseaux, E.; Maher, D. T.; Greening, C.

10.1101/2024.07.02.601631 — microbiology — Posted on 2024-07-03

4577 A novel infective endocarditis virulence factor related to multiple functions for bacterial survival in blood was discovered in Streptococcus sanguinis

Xu, P.; Anandan, V.; Bao, L.; Zhu, Z.; Bradley, J.; Assi, V.-F.; Chavda, H.; Kitten, T.

10.1101/2024.07.03.601854 — microbiology — Posted on 2024-07-03

4578 Competition and cooperation: The plasticity of bacteria interactions across environments

Solowiej-Wedderburn, J.; Pentz, J. T.; Lizana, L.; Schroder, B.; Lind, P.; Libby, E.

10.1101/2024.07.03.601864 — microbiology — Posted on 2024-07-03

4579 Influenza A defective viral genomes and non-infectious particles are in-creased by host PI3K inhibition via anti-cancer drug alpelisib

Agu, I.; Jose, I. R.; Ram, A.; Oberbauer, D.; Albeck, J. G.; Diaz-Munoz, S. L.

10.1101/2024.07.03.601932 — microbiology — Posted on 2024-07-03

4580 Mutations in the Staphylococcus aureus Global Regulator CodY Confer Tolerance to an Interspecies Redox-Active Antimicrobial

Martini, A. M.; Alexander, S. A.; Khare, A.

10.1101/2024.07.02.601769 — microbiology — Posted on 2024-07-03

4581 Ecology of prophage-like elements in Bacillus subtilis at global and local geographical scale

Stefanic, P.; Stare, E.; Floccari, V. A.; Kovac, J.; Hertel, R.; Rocha, U.; Kovacs, A. T.; Mandic-Mulec, I.; Strube, M. L.; Dragos, A.

10.1101/2024.07.03.601884 — microbiology — Posted on 2024-07-03

4582 Antimicrobial Profile from Frog Skin Peptides

Chi, Y.; Zhang, Y.; Wang, X.; Li, F.; Zhang, Z.

10.1101/2024.07.03.600345 — microbiology — Posted on 2024-07-03

4583 Developing, characterizing and modelingCRISPR-based point-of-use pathogen diagnostics

Jung, J. K.; Dreyer, K. S.; Dray, K. E.; Muldoon, J. J.; George, J.; Shirman, S.; Cabezas, M. D.; D'Aquino, A. E.; Verosloff, M. S.; Seki, K.; Rybnicky, G. A.; Alam, K. K.; Bagheri, N.; Jewett, M. C.; Leonard, J. N.; Mangan, N. M.; Lucks, J. B.

10.1101/2024.07.03.601853 — synthetic biology — Posted on 2024-07-03

4584 CRISPR-GEM: A Novel Machine Learning Model for CRISPR Genetic Target Discovery and Evaluation

Graham, J. P.; Zhang, Y.; He, L.; Gonzalez-Fernandez, T.

10.1101/2024.07.01.601587 — bioengineering — Posted on 2024-07-03

4585 Effect of truffle extracts on growth of Chlorella vulgaris

VLASOVA, A.; Lipatova, O. E.; Belyshenko, A. Y.; Martynova, E. I.; Imidoeva, N. A.; Telnova, T. Y.; Malygina, E. V.; Morgunova, M. M.; Dmitrieva, M. E.; Shelkovnikova, V. N.; Shashkina, S. S.; Vavilina, T. N.; Axenov-Gribanov, D.

10.1101/2024.07.03.601813 — biochemistry — Posted on 2024-07-03

4586 Molecular Insights into AGS3's Role in Spindle Orientation: A Biochemical Perspective

Yu, S.; Ji, J.; Liu, Z.; Wang, W.

10.1101/2024.07.02.601660 — biochemistry — Posted on 2024-07-03

4587 Cooperativity among clustered κB sites within promoters and enhancers dictates transcriptional specificity of NF-κB RelA along with specific cofactors

Shahabi, S.; Biswas, T.; Shen, Y.; Zou, Y.; Sanahmadi, R.; Ghosh, G.

10.1101/2024.07.03.601930 — biochemistry — Posted on 2024-07-03

4588 Genetic architecture of the thermal tolerance landscape of Drosophila melanogaster

Pinilla, F.; Soto, J.; Olguin, P. E.; Castaneda, L. E.

10.1101/2024.07.01.601629 — evolutionary biology — Posted on 2024-07-03

4589 Wolbachia incompatible insect technique program optimization over large spatial scales using a process-based model of mosquito metapopulation dynamics

Lim, P. L.; Cook, A. R.; Bansal, S.; Chow, J. Y.; Lim, J. T.

10.1101/2024.07.01.601531 — ecology — Posted on 2024-07-03

4590 Spatial proteomic mapping of human nuclear bodies reveals new functional insights into RNA regulation

Dyakov, B. J. A.; Kobelke, S.; Ahmed, B. R.; Wu, M.; Roth, J. F.; Kasmaeifar, V.; Lin, Z.-Y.; Youn, J.-Y.; Thivierge, C.; Campbell, K. R.; Duchaine, T. F.; Blencowe, B. J.; Fox, A. H.; Gingras, A.-C.

10.1101/2024.07.03.601239 — cell biology — Posted on 2024-07-03

4591 High Coverage Profiling of Tel1 Signaling Reveals a Predominant Non-Canonical Phospho-Motif

Comstock, W. J.; Sanford, E. J.; Navarro, M.; Smolka, M. B.

10.1101/2024.07.03.601872 — molecular biology — Posted on 2024-07-03

4592 Heat pre-treatment reduces multiplicity of plasmid transformations in yeast during electroporation, without diminishing the transformation efficiency

Wäneskog, M.; Hoch-Schneider, E. E.; Garg, S.; Kronborg Cantalapiedra, C.; Schaefer, E.; Krogh Jensen, M.; Damgaard Jensen, E.

10.1101/2024.07.03.601847 — microbiology — Posted on 2024-07-03

4593 Characterizing Excretory-Secretory Products Proteome Across Larval Development Stages in Ascaris suum

Castaneda, S.; Adeniyi-Ipadeola, G.; Wu, Y.; Suarez-Reyes, C.; Jain, A.; Ramirez Gonzalez, J. D.; Weatherhead, J.

10.1101/2024.07.03.601870 — microbiology — Posted on 2024-07-03

4594 Tubulin-Targeted Therapy in Melanoma Increases Cell Invasive Potential by Activation of Actomyosin Cytoskeleton - an in vitro study

Luty, M.; Szydlak, R.; Pabijan, J.; Zemla, J.; Oevreeide, I. H.; Prot, V. E.; Stokke, B. T.; Lekka, M.; Zapotoczny, B.

10.1101/2024.07.01.601575 — biophysics — Posted on 2024-07-03

4595 A Drug-Elicitable Alternative-Splicing Module (DreAM) for Tunable AAV Expression and Controlled Myocardial Regeneration

Chen, Z.; Yang, L.; Zhang, Y.; Li, Y.; Chen, G.; Wang, Z.; Li, J.; Yang, Y.; Zhao, D.; Pu, W. T.; Yang, K.; Dong, E.; Guo, Y.

10.1101/2024.07.01.601517 — bioengineering — Posted on 2024-07-03

4596 Comparison of Infinium MethylationEPIC v2.0 to v1.0 for human population epigenetics: considerations for addressing EPIC version differences in DNA methylation-based tools

Zhuang, B. C.; Jude, M. S.; Konwar, C.; Ryan, C. P.; Whitehead, J.; Engelbrecht, H.-R.; MacIsaac, J. L.; Dever, K.; Toan, T. K.; Korinek, K.; Zimmer, Z.; Huffman, K. M.; Lee, N. R.; McDade, T. W.; Kuzawa, C. W.; Belsky, D. W.; Kobor, M. S.

10.1101/2024.07.02.600461 — genomics — Posted on 2024-07-03

4597 Understanding glycaemia and glycation levels in birds: diet and life history traits associations

Moreno Borrallo, A.; Jaramillo Ortiz, S.; Schaeffer-Reiss, C.; Rey, B.; Quintard, B.; Viblanc, V. A.; Boulinier, T.; Bize, P.; S. Gutierrez, J.; Masero, J. A.; Bertile, F.; Criscuolo, F.

10.1101/2024.07.02.600014 — evolutionary biology — Posted on 2024-07-03

4598 Inference of ecological networks and possibilistic dynamics based on Boolean networks from observations and prior knowledge

Pauleve, L.; Gaucherel, C.

10.1101/2024.07.01.601264 — ecology — Posted on 2024-07-03

4599 Unexpected diversity and ecological significance of uncultivable large virus-like particles in aquatic environments

Billard, H.; Fuster, M.; Enault, F.; Carrias, J.-F.; Fargette, L.; Carrouee, M.; Desmares, P.; Delmont, T. O.; Bigeard, E.; Tanguy, G.; Nogaret, P.; Baudoux, A.-C.; Christaki, U.; Sime-Ngando, T.; Colombet, J.

10.1101/2024.07.03.599014 — ecology — Posted on 2024-07-03

4600 Restoration of Type 17 immune signaling is not sufficient for protection during influenza-associated pulmonary aspergillosis

AHMAD, A.; Singh, R.; Nickolich, K.; Pilewski, M.; Ngeow, C.; Frempong-Manso, K.; Robinson, K. M.

10.1101/2024.07.01.601559 — immunology — Posted on 2024-07-03

4601 Reduction of Deformed Wing Virus-B levels in Colonies of the Honey bee Apis mellifera after Queen Vaccination with inactivated Paenibacillus larvae

Weinberg, I. P.; Floyd, A.; Reid, N.; Swift, N.

10.1101/2024.07.01.601551 — immunology — Posted on 2024-07-03

4602 Reticulate leaf venation in Pilea peperomioides is a Voronoi diagram

Zheng, X.; Venezia, M.; Blum, E.; Pedmale, U. V.; Jackson, D.; Prusinkiewicz, P.; Navlakha, S.

10.1101/2024.07.01.601217 — plant biology — Posted on 2024-07-03

4603 Connexin 43 drives glioblastoma cancer stem cell phenotypes through a WNK lysine-deficient protein kinase 1-c-MYC signaling axis

Mulkearns-Hubert, E. E.; Hajdari, N.; Hong, E. S.; Jacobs, A. P.; Kay, K. E.; Wang, S. Z.; Silver, D. J.; Hubert, C. G.; Lathia, J. D.

10.1101/2024.07.01.601549 — cancer biology — Posted on 2024-07-03

4604 Limitations of Current Machine-Learning Models in Predicting Enzymatic Functions for Uncharacterized Proteins

de Crecy-Lagard, V.; Dias, R.; Friedberg, I.; Yuan, Y.; Swairjo, M.

10.1101/2024.07.01.601547 — bioinformatics — Posted on 2024-07-03

4605 GTestimate: Improving relative gene expression estimation in scRNA-seq using the Good-Turing estimator

Fahrenberger, M.; Esk, C.; von Haeseler, A.

10.1101/2024.07.02.601501 — bioinformatics — Posted on 2024-07-03

4606 Innate immune system signaling and CD11b+CD11c+CD103+ cell migration to the brain underlie changes in mouse behavior after microbial colonization.

Philip, V.; Kraimi, N.; Zhang, H.; Lu, J.; De Palma, G.; Shimbori, C.; McCoy, K. D.; Hapfelmeier, S.; Schaeren, O. P.; Macpherson, A.; Chirdo, F.; Surette, M. G.; Verdu, E. F.; Liu, F.; Collins, S. M.; Bercik, P.

10.1101/2024.07.03.600853 — animal behavior and cognition — Posted on 2024-07-03

4607 Measuring the effect of RFID and Marker Recognition tags on cockroach behaviour using AI aided tracking

McLean, C. J.; Fisher, D. N.

10.1101/2024.07.01.600705 — animal behavior and cognition — Posted on 2024-07-03

4608 Cryptic recombination and transposition drive structural variation to shape genomic plasticity and life history traits in a host generalist fungal plant pathogen

Derbyshire, M. C.; Newman, T. E.; Khentry, Y.; Michael, P. J.; Bennett, S. J.; Rijal Lamichhane, A.; Graham-Taylor, C.; Chander, S.; Camplone, C.; Vicini, S.; Esquivel-Garcia, L.; Buchwaldt, L.; Coutou, C.; Hegedus, D.; Clarkson, J.; Lindbeck, K.; Kamphuis, L. G.

10.1101/2024.07.02.600549 — genomics — Posted on 2024-07-03

4609 Bulk and Single-cell Transcriptomic Brain Data Identify Overlapping Processes and Cell-types with Human AUD and Mammalian Models of Alcohol Use

Huggett, S. B.; Selvaraj, S.; McGeary, J. E.; Ikeda, A.; Yuan, E.; Loeffel, L. B.; Palmer, R. H. C.

10.1101/2024.07.02.601528 — genetics — Posted on 2024-07-03

4610 RNA mis-splicing in children with myotonic dystrophy is associated with physical function

Hartman, J. M.; Ikegami, K.; Provenzano, M.; Bates, K.; Butler, A.; Jones, A. S.; Berggren, K. N.; Dekdebrun, J.; McKay, M. J.; Baldwin, J. N.; Cornett, K. M. D.; Burns, J.; Kiefer, M.; Johnson, N. E.; Hale, M. A.; DMCRN,

10.1101/2024.07.03.600889 — genetics — Posted on 2024-07-03

4611 SID-2 localises to extracellular vesicles in parasitic nematodes and does not function in environmental RNAi

Blow, F.; Jeffrey, K.; Wang-Ngai Chow, F.; Nikonorova, I. A.; Barr, M. M.; Cook, A. G.; Prevo, B.; Cheerambathur, D. K.; Buck, A. H.

10.1101/2024.07.03.599821 — evolutionary biology — Posted on 2024-07-03

4612 Specialized signaling centers direct cell fate and spatial organization in a limb organoid model

Skoufa, E.; Zhong, J.; Kahre, O.; Hu, K.; Tsissios, G.; Carrau, L.; Herrera, A.; Dominguez Mantes, A.; Ibeas, A.; Jang, H.; Weigert, M.; La Manno, G.; Lutolf, M. P.; Ros, M.; Aztekin, C.

10.1101/2024.07.02.601324 — developmental biology — Posted on 2024-07-03

4613 Ambivalent partnership of the Drosophila posterior class Hox protein Abdominal-B with the Extradenticle and Homothorax cofactors

Curt, J. R.; Martin, P.; Foronda, D.; Hudry, B.; Kannan, R.; Shetty, S.; Merabet, S.; Saurin, A.; Graba, Y.; Sanchez-Herrero, E.

10.1101/2024.07.03.601496 — developmental biology — Posted on 2024-07-03

4614 The ERK5 MAP kinase regulates annexin complexes and membrane dynamics in embryonic stem cells

Brown, H. A.; Guillet, L.; Williams, C. A.; Shaw, H.; Zhou, H.; Rios-Szwed, D.; Fernandez-Alonso, R.; McMulkin, L.; Stavridis, M. P.; Findlay, G. M.

10.1101/2024.07.03.598211 — developmental biology — Posted on 2024-07-03

4615 Exploring glioma heterogeneity through omics networks: from gene network discovery to causal insights and patient stratification

Kastendiek, N.; Coletti, R.; Gross, T.; Lopes, M. B.

10.1101/2024.07.02.601715 — bioinformatics — Posted on 2024-07-03

4616 Rampant Reticulation in a Rapid Radiation of Tropical Trees - Insights from Inga (Fabaceae)

Schley, R. J.; Pineiro, R.; Nicholls, J. A.; Pezzini, F. F.; Kidner, C.; Farbos, A.; Ringelberg, J. J.; Twyford, A. D.; Dexter, K. G.; Pennington, T.

10.1101/2023.09.12.557345 — evolutionary biology — Posted on 2024-07-03

4617 Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

Shipman, A.; Gao, Y.; Liu, D.; Sun, S.; Zang, J.; Sun, P.; Syed, Z.; Bhagavathi, A.; Smith, E.; Erickson, T.; Hill, M.; Neuhauss, S. C.; Sui, S.-F.; Nicolson, T.

10.1101/2024.03.13.584854 — neuroscience — Posted on 2024-07-03

4618 Flexible EMG arrays with integrated electronics for scalable electrode density

Anschutz, P. M.; Zia, M.; Lu, J.; Williams, M. J.; Jacob, A. L.; Sober, S. J.; Bakir, M. S.

10.1101/2024.07.02.601782 — neuroscience — Posted on 2024-07-03

4619 The genetics of fruit skin separation in date palm

Malek, J. A.; Younuskunju, S.; Mayer, K.; Mohamoud, Y. A.; Suhre, K.; Mathew, L. S.

10.1101/2024.07.01.601480 — bioinformatics — Posted on 2024-07-03

4620 Toward a generic feature set defined by consensus peaks as a consistent reference for ATAC-seq data

Meng, Q.; Wu, X.; Zhao, Y.; Chen, W.; Li, C.; Wei, Z.; Li, J.; Xi, X.; Chen, S.; Zhang, C.; Chen, S.; Li, J.; Wang, X.; Jiang, R.; Wei, L.; Zhang, X.

10.1101/2023.05.30.542889 — bioinformatics — Posted on 2024-07-03

4621 A novel induced pluripotent stem cell model of schwann cell differentiation reveals NF2-related gene regulatory networks of the extracellular matrix

Lazaro, O.; Li, S.; Carter, W.; Awosika, O.; Robertson, S.; Hickey, B. E.; Angus, S. P.; House, A.; Clapp, D. W.; Qadir, A. S.; Johnson, T. S.; Rhodes, S. D.

10.1101/2024.05.02.591952 — bioinformatics — Posted on 2024-07-03

4622 Large-scale genome analyses provide insights into Hymenoptera evolution

He, C.; Yang, Y.; Zhao, X.; Li, J.; Cai, Y.; Peng, L.; Liu, Y.; Xiong, S.; Mei, Y.; Yan, Z.; Wang, J.; Xiao, S.; Teng, Z.; Gao, X.; Xue, H.; Fang, Q.; Ye, G.; Ye, X.

10.1101/2024.07.01.601370 — genomics — Posted on 2024-07-03

4623 A High-quality Oxford Nanopore Assembly of the Hourglass Dolphin (Lagenorhynchus cruciger) Genome

McGrath, N.; le Roux, J.; Whibley, A.; Alexander, A.; Stewart, R. O.; Johnstone, M.; Stockin, K. A.; Silander, O. K.

10.1101/2024.05.30.596754 — genomics — Posted on 2024-07-03

4624 Optimizing multi-environment trials in the US Rice belt via smart-climate-soil prediction based-models and economic importance

Prado, M.; Famoso, A.; Guidry, K.; Fritsche-Neto, R.

10.1101/2024.07.02.601777 — genetics — Posted on 2024-07-03

4625 Wild yeast isolation by middle school students reveals features of North American oak populations of Saccharomyces cerevisiae and Kluyveromyces lactis

McMurray, M. A.; Yeager, R.; Heasley, L. R.; Baker, N.; Shrivastava, V.; Woodman, J.

10.1101/2024.06.27.601111 — evolutionary biology — Posted on 2024-07-03

4626 Time of arrival during plant disease progression and humidity additively influence Salmonella enterica colonization of lettuce

Dixon, M. H.; Nellore, D.; Zaacks, S. C.; Barak, J. D.

10.1101/2024.02.16.580743 — microbiology — Posted on 2024-07-03

4627 Quantification of heterogeneity in human CD8+ T cell responses to vaccine antigens: an HLA-guided perspective

Harris, D. C.; Shanker, A.; Montoya, M. M.; Llewellyn, T. R.; Matuszak, A. R.; Lohar, A.; Kubicek Sutherland, J. Z.; Li, Y. W.; Wilding, K.; Mcmahon, B.; Gnanakaran, S.; Ribeiro, R. M.; Perelson, A. S.; molina-paris, c.

10.1101/2024.07.02.601716 — immunology — Posted on 2024-07-03

4628 Single-cell transcriptomic changes in oligodendrocytes and precursors derived from Parkinson's disease patient-iPSCs with LRRK2-G2019S mutation

Dehestani, M.; Kessler, W.; Karmali, N.; Sun, W.; Tsitkov, S.; Dhingra, A.; Rodriguez-Nieto, S.; Tietz, J.; Schafflick, D.; Fernandes, N.; Fraenkel, E.; Gasser, T.; Kuhlmann, T.; Bansal, V.

10.1101/2024.07.01.601392 — neuroscience — Posted on 2024-07-03

4629 Explicit and implicit locomotor learning in individuals with chronic hemiparetic stroke

Wood, J. M.; Thompson, E. M.; Wright, H.; Festa, L.; Morton, S. M.; Reisman, D. S.; Kim, H. E.

10.1101/2024.02.04.578807 — neuroscience — Posted on 2024-07-03

4630 Preparatory attentional templates in prefrontal and sensory cortex encode target-associated information

Zhou, Z.; Geng, J. J.

10.1101/2024.07.01.601634 — neuroscience — Posted on 2024-07-03

4631 Neural correlates of nightmares revisited: findings from large-scale fMRI cohorts

Pereira, M.; Terpstra, N.; Rutiku, R.; Sandberg, K.; Dresler, M.; Krause, F.

10.1101/2024.07.02.601684 — neuroscience — Posted on 2024-07-03

4632 Single-cell proteomics of Arabidopsis leaf mesophyll identifies drought stress-related proteins

Fulcher, J. M.; Dawar, P.; Balasubramanian, V. K.; Williams, S. M.; Nadeau, K.; Winkler, T. E.; Markillie, L. M.; Mitchell, H. D.; Ahkami, A. H.; Pasa-Tolic, L.; Zhu, Y.

10.1101/2024.07.01.601628 — plant biology — Posted on 2024-07-03

4633 Molecular control of dormancy transitions throughout the year in the monoecious cork oak

Silva, H. G.; Sobral, R.; Alhinho, A. T. T.; Afonso, H. R.; Ribeiro, T.; Silva, P.; Bousbaa, H.; Morais-Cecilio, L.; Costa, M. M. R.

10.1101/2024.07.03.601814 — plant biology — Posted on 2024-07-03

4634 Reporter-based screening identifies RAS-RAF stabilizing mutations as drivers of resistance to broad-spectrum RAS inhibition in colorectal cancer

Aust, O.; Blanc, E.; Lüthen, M.; Hollek, V.; Astaburuaga-Garcia, R.; Klinger, B.; Trinks, A.; Beule, D.; Papke, B.; Horst, D.; Bluthgen, N.; Sers, C.; Der, C.; Morkel, M.

10.1101/2024.07.01.601542 — cancer biology — Posted on 2024-07-03

4635 Aging-associated Alterations in the Gene Regulatory Network Landscape Associate with Risk, Prognosis and Response to Therapy in Lung Adenocarcinoma

Saha, E.; Ben Guebila, M.; Fanfani, V.; Shutta, K. H.; DeMeo, D. L.; Quackenbush, J.; Lopes-Ramos, C. M.

10.1101/2024.07.02.601689 — cancer biology — Posted on 2024-07-03

4636 Multiomics data analysis identifies TM4SF4 as a cell surface target in hepatocellular carcinoma

Wong, K. K.; Ab Hamid, S. S.

10.1101/2024.07.01.601537 — cancer biology — Posted on 2024-07-03

4637 Fluorescence labeling strategies for the study of ion channel and receptor cell surface expression: A comprehensive toolkit for extracellular labeling of TRPV1.

Mott, T. M.; Wulffraat, G. C.; Eddins, A. J.; Mehl, R. A.; Senning, E. N.

10.1101/2024.05.09.593209 — biophysics — Posted on 2024-07-03

4638 Surpassing Light Inhomogeneities in Structured-Illumination Microscopy with FlexSIM

Soubies, E.; Nogueron, A.; Pelletier, F.; Mangeat, T.; Leterrier, C.; Unser, M.; Sage, D.

10.1101/2023.12.20.572677 — biophysics — Posted on 2024-07-03

4639 MetaKSSD: Boosting the Scalability of Reference Taxonomic Marker Database and the Performance of Metagenomic Profiling Using Sketch Operations

Yi, H.

10.1101/2024.06.21.600011 — bioinformatics — Posted on 2024-07-03

4640 Imaging Intra- and Extracellular Conductivity using MR based Conductivity Tensor Imaging

Rana, N.; Katoch, N.

10.1101/2024.07.01.601471 — bioengineering — Posted on 2024-07-03

4641 Microglia Morphological Response to Mesenchymal Stromal Cell Extracellular Vesicles Demonstrates EV Therapeutic Potential for Modulating Neuroinflammation

Daga, K. R.; Larey, A. M.; Morfin, M. G.; Chen, K.; Bitarafan, S.; Carpenter, J. M.; Hynds, H. M.; Hines, K. M.; Wood, L. B.; Marklein, R. A.

10.1101/2024.07.01.601612 — bioengineering — Posted on 2024-07-03

4642 Structural basis for transcription activation through cooperative recruitment of MntR

Shi, H.; Fu, Y.; Kodyte, V.; Andreas, A.; Sachla, A.; Miller, K.; Shrestha, R.; Helmann, J. D.; Glasfeld, A.; Ahuja, S.

10.1101/2024.06.28.601288 — biochemistry — Posted on 2024-07-03

4643 Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging

Occean, J. R.; Yang, N.; Sun, Y.; Dawkins, M. S.; Munk, R.; Belair, C.; Dar, S.; Anerillas, C.; Wang, L.; Shi, C.; Dunn, C.; Bernier, M.; Price, N. L.; Kim, J. S.; Cui, C.-Y.; Fan, J.; Bhattacharyya, M.; De, S.; Maragkakis, M.; Cabo, R. d.; Sidoli, S.; Sen, P.

10.1101/2023.02.15.528714 — genomics — Posted on 2024-07-03

4644 Mechanistic target of rapamycin (mTOR) pathway in Sertoli cells regulates age-dependent changes in sperm DNA methylation

Amir, S.; Arowolo, O.; Mironova, E.; McGaunn, J.; Oluwayiose, O.; Sergeyev, O.; Pilsner, J. R.; Suvorov, A.

10.1101/2023.05.23.541978 — developmental biology — Posted on 2024-07-03

4645 Fructose consumption in pregnancy and associations with maternal and offspring hepatic and whole-body adiposity: a scoping review.

Zhao, G.; Chondon, S.; Gray, C.; Gentili, S.; Stanley, M.; Regnault, T.

10.1101/2024.07.02.600389 — developmental biology — Posted on 2024-07-03

4646 Design, infectability, and transcriptomic analysis of transregionally differentiated and scalable lung organoids derived from adult bronchial cells.

Reyes Valenzuela, A.; Turner, M.; Markarian, N.; Lachance-Brais, C.; Hanrahan, J. W.; Vali, H.; Vidal, S.; Mongeau, L.

10.1101/2024.07.02.601655 — cell biology — Posted on 2024-07-03

4647 Activation of ATF3 via the Integrated Stress Response Pathway Regulates Innate Immune Response to Restrict Zika Virus.

Badu, P.; Baniulyte, G.; Sammons, M. A.; Pager, C. T.

10.1101/2023.07.26.550716 — microbiology — Posted on 2024-07-03

4648 Nepali oral microbiomes reflect a gradient of lifestyles from traditional to industrialized

Ryu, E. P.; Gautam, Y.; Proctor, D. M.; Bhandari, D.; Tandukar, S.; Gupta, M.; Gautam, G. P.; Relman, D. A.; Shibl, A. A.; Sherchand, J. B.; Jha, A. R.; Davenport, E. R.

10.1101/2024.07.01.601557 — microbiology — Posted on 2024-07-03

4649 Cognitive neuropsychological and neuroanatomic predictors of naturalistic action performance in left hemisphere stroke: a retrospective analysis

Thibault, S.; Wong, A. L.; Buxbaum, L. J.

10.1101/2024.07.01.601398 — neuroscience — Posted on 2024-07-03

4650 A spatially resolved multiomic single-cell atlas of soybean development

Zhang, X.; Luo, Z.; Marand, A. P.; Yan, H.; Jang, H.; Bang, S.; Mendieta, J. P.; Minow, M. A. A.; Schmitz, R. J.

10.1101/2024.07.03.601616 — plant biology — Posted on 2024-07-03

4651 CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti-tumoral compounds

Amarilla-Quintana, S.; Navarro, P.; Ramos, A.; Montero-Calle, A.; Cabezas-Sainz, P.; Barrero, M. J.; Megias, D.; Vilaplana-Marti, B.; Epifano, C.; Gomez-Dominguez, D.; Hernandez, I.; Monzon, S.; Cuesta, I.; Sanchez, L.; Barderas, R.; Garcia-Donas, J.; Martin, A.; Perez de Castro, I.

10.1101/2024.07.01.601520 — cancer biology — Posted on 2024-07-03

4652 PENGUIN: A rapid and efficient image preprocessing tool for multiplexed spatial proteomics

Sequeira, A. M.; Ijsselsteijn, M. E.; Rocha, M.; de Miranda, N. F. C. C.

10.1101/2024.07.01.601513 — bioinformatics — Posted on 2024-07-03

4653 Upregulation of a nonsense mediated decay (NMD) insensitive CFTR mRNA isoform has therapeutic potential for the treatment of 3 Prime CFTR PTC variants

Allaire, N. E.; Armstrong, M.; Yoon, J. S.; Bhatt, P.; Harrington, J.; Cheng, Y.; Valley, H.; Macadino, C.; Bihler, H.; Sivachenko, A.; Mense, M.; Cotton, C.

10.1101/2024.07.01.601512 — genomics — Posted on 2024-07-03

4654 HCV- and HBV-mediated liver cancer converge on similar transcriptomic landscapes and immune profiles.

Borden, E.; Jorgensen, A.; Natri, H. M.; Hastings, K. T.; Buetow, K. H.; Wilson, M. A.

10.1101/2024.07.01.601493 — genetics — Posted on 2024-07-03

4655 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years

Bougiouri, K.; Aninta, S. G.; Charlton, S.; Harris, A.; Carmagnini, A.; Piliciauskiene, G.; Feuerborn, T. R.; Scarsbrook, L.; Tabadda, K.; Blazevicius, P.; Parker, H. G.; Gopalakrishnan, S.; Larson, G.; Ostrander, E. A.; Irving-Pease, E. K.; Frantz, L. A. F.; Racimo, F.

10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-07-03

4656 Towards edge processing of images from insect camera traps

Bjerge, K.; Karstoft, H.; Hoye, T. T.

10.1101/2024.07.01.601488 — ecology — Posted on 2024-07-03

4657 Sphingosine kinase 1 is integral for elastin deficiency-induced arterial hypermuscularization

Saito, J.; Dave, J. M.; Gallardo-Vara, E.; Kabir, I.; Tellides, G.; Riemer, R. K.; Urban, Z.; Hla, T.; Greif, D. M.

10.1101/2024.07.01.601150 — developmental biology — Posted on 2024-07-03

4658 A Vago-like gene enhances dengue and Zika virus dissemination in Aedes aegypti

Couderc, E.; Crist, A. B.; Daron, J.; Varet, H.; Van Hout, F. A. H.; Miesen, P.; Palatini, U.; Dabo, S.; Vial, T.; LAMBRECHTS, L.; Merkling, S.

10.1101/2024.07.01.601473 — immunology — Posted on 2024-07-03

4659 Activated NK cells with a predominance of inhibitory receptors and a decidual-like phenotype expand after autologous HSCT in children with tumors.

Astarloa-Pando, G.; Polanco-Alonso, D.; Sanda, V.; Orrantia, A.; Amarilla-Irusta, A.; Perez-Fernandez, S.; Perez-Garay, R.; Sevilla, A.; Lopez-Pardo, A.; Tijero, A.; Uriz, J. J.; Rey, M.; Astigarraga, I.; Manzanares-Martin, B.; Bediaga, N. G.; Amo, L.; Zenarruzabeitia, O.; Borrego, F.

10.1101/2024.07.01.601507 — immunology — Posted on 2024-07-03

4660 Startling acoustic stimuli hasten choice reaching tasks by strengthening, but not changing the timing of, express visuomotor responses

Weerdesteyn, V.; Kearsley, S. L.; Cecala, A. L.; MacPherson, E. A.; Corneil, B. D.

10.1101/2024.07.01.601510 — neuroscience — Posted on 2024-07-03

4661 The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

Feringa, F. M.; Koppes-den Hertog, S. J.; Wang, L.; Derks, R. J. E.; Kruijff, I.; Erlebach, L.; Heijneman, J.; Miramontes, R.; Pömpner, N.; Blomberg, N.; Olivier-Jimenez, D.; Johanson, L. E.; Cammack, A. J.; Giblin, A.; Toomey, C. E.; Rose, I. V. L.; Yuan, H.; Ward, M. E.; Isaacs, A.; Kampmann, M.; Kronenberg-Versteeg, D.; Lashley, T.; Thompson, L. M.; Ori, A.; Mohammed, Y.; Giera, M.; van der Kant, R. H. N.

10.1101/2024.07.01.601474 — neuroscience — Posted on 2024-07-03

4662 A novel behavioral paradigm using mice to study predictive postural control

Doi, Y.; Asaka, M.; Born, R. T.; Yanagihara, D.; Uchida, N.

10.1101/2024.07.01.601478 — neuroscience — Posted on 2024-07-03

4663 The Soybean Cyst Nematode Effector Cysteine Protease 1 (CPR1) Targets a Mitochondrial Soybean Branched-Chain Amino Acid Aminotransferase (GmBCAT1) for Degradation

Margets, A.; Foster, J.; Kumar, A.; Maier, T.; Masonbrink, R. E.; Mejias, J.; Baum, T. J.; Innes, R. W.

10.1101/2024.07.01.601533 — plant biology — Posted on 2024-07-03

4664 Camelina CircRNA Landscape: Implications for Gene Regulation and Fatty Acid Metabolism

Utley, D.; Edwards, B.; Budnick, A.; Grotewold, E.; Sederoff, H.

10.1101/2024.07.02.601705 — plant biology — Posted on 2024-07-03

4665 DWARF14 and KARRIKIN INSENSITIVE2 mediate signaling of the apocarotenoid zaxinone in Arabidopsis

Moreno Beltran, J. C.; Shahul Hameed, U. F.; Balakrishna, A.; Ablazov, A.; Liew, K. X.; Jamil, M.; Mi, J.; Alashoor, K.; de Saint Germain, A.; Arold, S. T.; Al-Babili, S.

10.1101/2024.07.03.601835 — plant biology — Posted on 2024-07-03

4666 DNA methylation database for gynecological cancer detection, classification and assay development

Boers, J.; Boers, R.; Sakoltchik, J.; Dasgupta, S.; Martens, L.; Tadema, K.; Prevoo, F.; Van IJcken, W.; Van den Munckhof, H.; Quint, W.; Van Beekhuizen, H.; Quint, W. H.; Van Kemenade, F.; Gribnau, J.

10.1101/2024.07.01.601485 — cancer biology — Posted on 2024-07-03

4667 Early ctDNA kinetics as a dynamic biomarker of cancer treatment response

Li, A. K.; Lou, E.; Leder, K.; Foo, J.

10.1101/2024.07.01.601508 — cancer biology — Posted on 2024-07-03

4668 Multiplatform molecular profiling and functional genomic screens identify prognostic signatures and mechanisms underlying MEK inhibitor response in somatic NF1 mutant glioblastoma

Pan, S.; Mirchia, K.; Payne, E.; Liu, S. J.; Al-Adli, N.; Peeran, Z.; Shukla, P.; Young, J. S.; Gupta, R.; Wu, J.; Pak, J.; Seo, K.; Ozawa, T.; Na, B.; Reddy, A. T.; Braunstein, S. E.; Phillips, J. J.; Chang, S.; Solomon, D. A.; Perry, A.; Raleigh, D. R.; Berger, M. S.; Abate, A. R.; Vasudevan, H. N.

10.1101/2024.07.01.601334 — genomics — Posted on 2024-07-03

4669 A transphyletic study of metazoan β-catenin protein complexes

Mbogo, I.; Kawano, C.; Nakamura, R.; Tsuchiya, Y.; Villar-Briones, A.; Hirao, Y.; Yasuoka, Y.; Hayakawa, E.; Tomii, K.; Watanabe, H.

10.1101/2024.07.01.600363 — evolutionary biology — Posted on 2024-07-03

4670 A theoretical framework linking the birth-death and protracted birth-death models, with implications for the phylogenetic analysis of diversification

Veron, P.; Andreoletti, J.; Giraud, T.; Morlon, H.

10.1101/2024.07.01.601000 — evolutionary biology — Posted on 2024-07-03

4671 Contributions of source populations, habitat suitability and trait overlap to benthic invertebrate community assembly in restored urban streams

Gillmann, S. M.; Schuwirth, N.; Lorenz, A. W.; Hering, D.

10.1101/2024.07.01.601525 — ecology — Posted on 2024-07-03

4672 Characterisation of aphid antixenosis in aphid-resistant ancestor wheat, Triticum monococcum

Borg, A. N.; Vuts, J.; Caulfield, J. C.; Withall, D. M.; Foulkes, J.; Birkett, M. A.

10.1101/2024.07.01.601505 — ecology — Posted on 2024-07-03

4673 Oviductin sets the species-specificity of the mammalian zona pellucida

de la Fuente, D.; Maroto, M.; Cajas, Y. N.; Canon-Beltran, K.; Fernandez-Gonzalez, R.; Munoz-Maceda, A.; Sanchez-Puig, J. M.; Blasco, R.; Cots, P.; Aviles, M.; Rizos, D.; Gutierrez-Adan, A.

10.1101/2024.07.01.601502 — developmental biology — Posted on 2024-07-03

4674 EFL-3/E2F7 modulates Wnt signalling through repressing the LIT-1 Nemo-like kinase during asymmetric epidermal cell division in Caenorhabditis elegans

Ferrando-Marco, M.; Barkoulas, M.

10.1101/2024.07.01.601538 — developmental biology — Posted on 2024-07-03

4675 A broad cathepsin inhibitor blocks crystal-stimulated inflammasome-dependent and -independent inflammation, and gout arthritis

Orellano, L. A. A.; Zeng, C.; Zhu, J.; Bogyo, M.; Rock, K.; LAI, J.-J.

10.1101/2024.07.01.601464 — immunology — Posted on 2024-07-03

4676 Fgf23 expression increases atherosclerotic plaque burden in male ApoE deficient mice

Lindberg, K.; Ovchinnikova, O.; Moor, M. B.; Pirault, J.; Ketelhuth, D. F. J.; Olauson, H.; Hansson, G. K.; Larsson, T. E.

10.1101/2024.07.01.601461 — physiology — Posted on 2024-07-03

4677 Development of a Deep Learning model Tailored for HER2 Detection in Breast Cancer to aid pathologists in interpreting HER2-Low cases

Bannier, P.-A.; Broeckx, G.; Herpin, L.; Dubois, R.; Van Praet, L.; Maussion, C.; Deman, F.; Amonoo, E.; Mera, A.; Timbres, J.; Gillett, C.; Sawyer, E.; Gazinska, P.; Ziolkowski, P.; Lacroix-Triki, M.; Salgado, R.; Irshad, S.

10.1101/2024.07.01.601397 — pathology — Posted on 2024-07-03

4678 UNRAVELING THE LUNG VASCULAR REMODELING IN PULMONARY HYPERTENSION USING A QUANTITATIVE DIGITAL PATHOLOGY SOFTWARE

Serdjebi, C.; Chandes, F.; Biernat, M.; Lepoivre, B.; Salvail, D.; Laurent, C. E.

10.1101/2024.07.01.601469 — pathology — Posted on 2024-07-03

4679 New soft tissue data of pterosaur tail vane reveals sophisticated, dynamic tensioning usage and expands its evolutionary origins

Jagielska, N.; Kaye, T. G.; Habib, M. B.; Hirasawa, T.; Pittman, M.

10.1101/2024.07.01.601487 — paleontology — Posted on 2024-07-03

4680 GenoTools: An Open-Source Python Package for Efficient Genotype Data Quality Control and Analysis

Vitale, D.; Koretsky, M.; Kuznetsov, N.; Hong, S.; Martin, J.; James, M.; Makarious, M. B.; Leonard, H.; Iwaki, H.; Faghri, F.; Blauwendraat, C.; Singleton, A. B.; Song, Y.; Levine, K.; Sreelatha, A. A. K.; Fang, Z.-H.; Nalls, M. A.

10.1101/2024.03.26.586362 — genomics — Posted on 2024-07-03

4681 Dynamics of X chromosome hyper-expression and inactivation in male tissues during stick insect development

Djordjevic, J.; Tran Van, P.; Toubiana, W.; Labedan, M.; Dumas, Z.; Aury, J.-M.; Cruaud, C.; Istace, B.; Labadie, K.; Noel, B.; Parker, D. J.; Schwander, T.

10.1101/2024.07.01.601468 — evolutionary biology — Posted on 2024-07-03

4682 Formation of multinucleated osteoclasts depends on an oxidized species of cell surface associated La protein

Leikina, E.; Whitlock, J. M.; Melikov, K.; Zhang, W.; Bachmann, M. P.; Chernomordik, L.

10.1101/2024.05.02.592254 — cell biology — Posted on 2024-07-03

4683 The combination of stimulus-driven and modulatory inputs in visual thalamus depend on visual responsiveness and stimulus type

Schmors, L.; Kotkat, A.; Bauer, Y.; Huang, Z.; Crombie, D.; Meyerolbersleben, L.; Sokoloski, S.; Berens, P.; Busse, L.

10.1101/2023.10.18.562960 — neuroscience — Posted on 2024-07-03

4684 Orthogonalization of spontaneous and stimulus-driven activity by hierarchical neocortical areal network in primates

Matsui, T.; Hashimoto, T.; Murakami, T.; Uemura, M.; Kikura, K.; Kato, T.; Ohki, K.

10.1101/2024.07.01.601463 — neuroscience — Posted on 2024-07-03

4685 HHV-6B, HHV-7, and B19V Are Frequently Found DNA Viruses in the Human Thymus but Show No Definitive Link with Myasthenia Gravis

NOWLAN, K.; Hannolainen, L.; Assimakopoulou, I. M.; Durnsteiner, P.; Sarkkinen, J.; Suokas, S.; Hedman, L.; Tienari, P. J.; Hedman, K.; Niku, M.; Aaltonen, L.-M.; Huuskanen, A.; Rasanen, J.; Ilonen, I. K.; Mayranpaa, M. I.; Dunkel, J.; Laakso, S. M.; Soderlund-Venermo, M.; Perdomo, M. F.; Kekalainen, E.

10.1101/2024.06.27.600940 — immunology — Posted on 2024-07-03

4686 Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke

Anwar, F.; Mosley, M.-T.; Jasbi, P.; Chi, J.; Gu, H.; Jadavji, N. M.

10.1101/2024.06.29.601358 — neuroscience — Posted on 2024-07-03

4687 Social predation by a nudibranch mollusc

Otter, K.; Gamidova, S.; Katz, P. S.

10.1101/2024.07.01.600874 — animal behavior and cognition — Posted on 2024-07-03

4688 A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae: Phoxinus phoxinus) provide evidence of haplotype diversity

Oriowo, T. O.; Chrysostomakis, I.; Martin, S.; Kukowka, S.; Brown, T.; Winkler, S.; Myers, E. W.; Boehne, A.; Stange, M.

10.1101/2023.11.30.569369 — genomics — Posted on 2024-07-03

4689 Insights into the metabolic consequences of type 2 diabetes

Bocher, O.; Singh, A.; Huang, Y.; Vosa, U.; Reimann, E.; Arruda, A.; Barysenska, A.; Kolde, A.; Rayner, N. W.; Esko, T.; Mägi, R.; Zeggini, E.

10.1101/2024.06.20.599832 — genomics — Posted on 2024-07-03

4690 A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity

Easwaran, S.; Montell, D.

10.1101/2024.03.10.584341 — genetics — Posted on 2024-07-03

4691 Chromosome X Dosage Modulates Development of Aneuploidy in Genetically Diverse Mouse Embryonic Stem Cells

Stanton, A.; Aydin, S.; Skelly, D. A.; Stavish, D.; Leonhard, K. A.; McIntire, E.; Pankratz, M.; Czechanski, A.; Ludwig, T.; Choi, T.; Gygi, S. P.; Barbaric, I.; Munger, S. C.; Reinholdt, L. G.; PERA, M. F.

10.1101/2024.06.29.601344 — genetics — Posted on 2024-07-03

4692 Bird brains fit the bill: morphological diversification and the evolution of avian brain size

Song, Z.; Drobniak, S. M.; Liu, Y.; van Schaik, C. P.; Griesser, M.

10.1101/2024.07.02.601652 — evolutionary biology — Posted on 2024-07-03

4693 Convergent reductive evolution in bee-associated lactic acid bacteria

Pontes, A.; Harrison, M.-C.; Rokas, A.; Goncalves, C.

10.1101/2024.06.28.601270 — evolutionary biology — Posted on 2024-07-03

4694 One Method to Sequence Them All? Comparison between Whole-Genome Sequencing (WGS) and Target Enrichment (TE) of museum specimens from the moth families Epicopeiidae and Sematuridae (Lepidoptera)

Call, E.; Twort, V. G.; Espeland, M.; Wahlberg, N.

10.1101/2023.08.21.553699 — evolutionary biology — Posted on 2024-07-03

4695 A Biparatopic Intrabody Renders Vero Cells Impervious to Ricin Intoxication

Czajka, T.; Vance, D. J.; Song, R.; Mantis, N. J.

10.1101/2024.07.02.601761 — immunology — Posted on 2024-07-03

4696 Unsilenced inhibitory cortical ensemble gates remote memory retrieval

Wang, S.; Sheng, T.; Su, F.; Yang, H.; Cao, R.; Wang, Q.; Zhang, C.; Lu, W.

10.1101/2024.07.01.601454 — neuroscience — Posted on 2024-07-03

4697 Physiological Harmony or Discord? Unveiling the Correspondence Between Subjective Arousal, Valence and Physiological Responses

Koppold, A.; Lonsdorf, T. B.; Kuhn, M.; Weymar, M.; Ventura-Bort, C.

10.1101/2024.05.31.596899 — neuroscience — Posted on 2024-07-03

4698 1.94 Angstrom structure of synthetic alpha-synuclein fibrils seeding MSA neuropathology

Burger, D.; Kashyrina, M.; Lewis, A. J.; De Nuccio, F.; Mohammed, I.; de La Seigliere, H.; van den Heuvel, L.; Verchere, J.; Feuillie, C.; Berbon, M.; Arotcarena, M.-L.; Retailleau, A.; Bezard, E.; Laferriere, F.; Loquet, A.; Bousset, L.; Baron, T.; Lofrumento, D. D.; De Giorgi, F.; Stahlberg, H.; Ichas, F.

10.1101/2024.07.01.601498 — neuroscience — Posted on 2024-07-03

4699 MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes

Vue, Z.; Murphy, A. C.; Le, H.; Neikirk, K.; Lopez, E. G.; Marshall, A. G.; Mungai, M.; Jenkins, B. C.; Vang, L.; Beasley, H.; Ezedimma, M.; Manus, S. A.; Whiteside, A.; Forni, M. F.; Harris, C.; Crabtree, A.; Albritton, C. F.; Jamison, S.; Demirci, M.; Prasad, P.; Oliver, A.; Actkins, K.; Shao, J.; Zaganjor, E.; Scudese, E.; Rodriguez, B. I.; Koh, A.; Rabago, I.; Moore, J.; Nguyen, D.; Aftab, M.; Kirk, B.; Li, Y.; Wandira, N.; Ahmad, T.; Saleem, M.; Kadam, A. A.; Katti, P.; Koh, H.-J.; Evans, C.; Koo, Y. D.; Wang, E.; Smith, Q.; Tomar, D.; Williams, C. R.; Sweetwyne, M. T.; Quintana, A.; Phil

10.1101/2024.06.20.599846 — physiology — Posted on 2024-07-03

4700 Phosphodiesterase 3 inhibitors boost bone outgrowth

Kawabe, T.; Ichimura, A.; Yasue, T.; Li, J.; Kim, G. E.; Ishikawa, H.; Ueda, Y.; Itoh, H.; Nishi, M.; Takeshima, H.

10.1101/2024.07.01.601482 — pharmacology and toxicology — Posted on 2024-07-03

4701 Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

Jepsen, V. H.; Hanel, A.; Picard, D.; Mehtonen, J.; Hasselmann, R.; Schliehe-Diecks, J.; Tu, J.-W.; Bhave, R.; Kameri, E.; Qin, N.; Wang, H.; Zhuang, Z.; Wagener, R.; Blümel, L.; Lautwein, T.; Hein, D.; Kögler, G.; Remke, M.; Bhatia, S.; Heinäniemi, M.; Borkhardt, A.; Fischer, U.; Scharov, K.

10.1101/2024.06.28.601221 — cancer biology — Posted on 2024-07-03

4702 Suppression of miRs-497/195 axis possibly confers endocrine therapy resistance via elevated expression of FLT4 and the noncoding RNA MIR503HG

Pramanik, S.; Das, P.; Mukherjee, M.; Desai, K. V.

10.1101/2024.05.14.594132 — cancer biology — Posted on 2024-07-03

4703 Deciphering circulating tumor cells binding in a microfluidic system thanks to a parameterized mathematical model

Ciavolella, G.; Granet, J.; Osmani, N.; Goetz, J. G.; Etchegaray, C.; Collin, A.

10.1101/2023.10.18.562910 — cancer biology — Posted on 2024-07-03

4704 Effective mechanical potential of cell-cell interaction in tissues harboring cavity and in cell sheet toward morphogenesis

Koyama, H.; Okumura, H.; Otani, T.; Ito, A. M.; Nakamura, K.; Kato, K.; Fujimori, T.

10.1101/2023.08.28.555208 — biophysics — Posted on 2024-07-03

4705 The fully activated open state of KCNQ1 controls the cardiac 'fight-or-flight' response

HOU, P.; ZHAO, L.; ZHONG, L.; Shi, J.; WANG, H.; GAO, J.; LIU, H.; Zuckerman, J.; COHEN, I. S.; Cui, J.

10.1101/2024.07.02.601749 — biophysics — Posted on 2024-07-03

4706 FAPM: Functional Annotation of Proteins using Multi-Modal Models Beyond Structural Modeling

Xiang, W.; Xiong, Z.; Huan, C.; Xiong, J.; Zhang, W.; Fu, Z.; Zheng, M.; Liu, B.; Shi, Q.

10.1101/2024.05.07.593067 — bioinformatics — Posted on 2024-07-03

4707 Gap-App: A sex-distinct AI-based predictor for pancreatic ductal adenocarcinoma survival as a web application open to patients and physicians

Ojha, A.; Zhao, S.-J.; Zhang, J.-T.; Simo, K. A.; Liu, J.-Y.

10.1101/2024.06.04.597246 — bioinformatics — Posted on 2024-07-03

4708 GET: a foundation model of transcription across human cell types

Fu, X.; Mo, S.; Buendia, A.; Laurent, A.; Shao, A.; Alvares-Torres, M. d. M.; Yu, T.; Tan, J.; Su, J.; Sagatelian, R.; Ferrando, A. A.; Ciccia, A.; Lan, Y.; Owens, D. M.; Palomero, T.; Xing, E. P.; Rabadan, R.

10.1101/2023.09.24.559168 — bioinformatics — Posted on 2024-07-03

4709 DualNetGO: A Dual Network Model for Protein Function Prediction via Effective Feature Selection

Chen, Z.; Luo, Q.

10.1101/2023.11.29.569192 — bioinformatics — Posted on 2024-07-03

4710 Accurate Bayesian phylogenetic point estimation using a tree distribution parameterized by clade probabilities

Berling, L.; Klawitter, J.; Bouckaert, R.; Xie, D.; Gavryushkin, A.; Drummond, A.

10.1101/2024.02.20.581316 — bioinformatics — Posted on 2024-07-03

4711 A Data-Intelligence-Intensive Bioinformatics Copilot System for Large-scale Omics Researches and Scientific Insights

Liu, Y.; Shen, R.; Zhou, L.; Xiao, Q.; Yuan, J.; Li, Y.

10.1101/2024.05.19.594895 — bioinformatics — Posted on 2024-07-03

4712 Visual quality control with CytoMDS, a Bioconductor package for low dimensional representation of cytometry sample distances

Hauchamps, P.; Delandre, S.; Temmerman, S. T.; Lin, D.; Gatto, L.

10.1101/2024.07.01.601465 — bioinformatics — Posted on 2024-07-03

4713 Revolutionizing Molecular Cloning: Introducing FastCloneAssist, a Streamlined Python Tool for Optimizing Primer Design in Restriction & Ligation-Independent PCR Cloning

Singh, P. K.; Donnenberg, M. S.

10.1101/2024.06.28.601205 — bioengineering — Posted on 2024-07-03

4714 Identification of the Mode of Evolution in Incomplete Carbonate Successions

Hohmann, N.; Koelewijn, J. R.; Burgess, P.; Jarochowska, E.

10.1101/2023.12.18.572098 — evolutionary biology — Posted on 2024-07-03

4715 E3 ligase Praja1 mediates ubiquitination and degradation of microtubule-associated protein Tau

Aoki, S.; Kawasaki, K.; Imadegawa, K.; Oishi, M.; Asahi, T.; Onodera, W.

10.1101/2024.06.10.598176 — biochemistry — Posted on 2024-07-03

4716 Experimental design impacts the vector competence of Ornithodoros ticks for African swine fever virus: a meta-analysis of published evaluations

Bernard, J.; Madeira, S.; Otte, J.; Boinas, F.; Le Potier, M.-F.; Vial, L.; Jourdan-Pineau, H.

10.1101/2023.11.10.566648 — ecology — Posted on 2024-07-03

4717 Engineering dynamic gates in binding pocket of penicillin G acylase to selectively degrade bacterial signaling molecules

Grulich, M.; Surpeta, B.; Palyzova, A.; Maresova, H.; Zahradnik, J.; Brezovsky, J.

10.1101/2023.05.09.538545 — biochemistry — Posted on 2024-07-03

4718 Prickle2 regulates apical junction remodeling and tissue fluidity during vertebrate neurulation

Matsuda, M.; Sokol, S. Y.

10.1101/2024.07.02.601771 — developmental biology — Posted on 2024-07-03

4719 Unravelling the progression of the zebrafish primary body axis with reconstructed spatiotemporal transcriptomics

Dong, Y.; Cheng, T.; Liu, X.; Fu, X.-x.; Hu, Y.; Yang, X.-F.; Yang, L.; Li, H.-R.; Bian, Z.-W.; JING, N.; Liao, J.; Fan, X.; Xu, P.-F.

10.1101/2024.07.01.601472 — developmental biology — Posted on 2024-07-03

4720 Regulation of the poly(A) Polymerase Star-PAP by a Nuclear Phosphoinositide Signalosome

Wen, T.; Chen, M.; Cryns, V. L.; Anderson, R. A.

10.1101/2024.07.01.601467 — cell biology — Posted on 2024-07-03

4721 Identification of small molecule agonists of fetal hemoglobin expression for the treatment of sickle cell disease

Yang, J.-P.; Toughiri, R.; Gounder, A.; Scheibe, D.; Petrus, M.; Fink, S.; Vallee, S.; Langston, S.; Kenniston, J.; Papaioannou, N.; Gavva, N.; Horman, S.

10.1101/2024.07.01.601536 — cell biology — Posted on 2024-07-03

4722 Prenylation controls proliferation in human pluripotent stem cell-derived cardiomyocytes

Batho, C.; Reid, J.; Robinson, H.; Cserne Szappanos, H.; Devilee, L.; Hoyte, S.; Johnston, R.; Ziegman, R.; Hassan, S.; Soday, L.; Fitzsimmons, R.; Foster, S.; Ng, D.; Tate, E. W.; Porrello, E. R.; Parker, B.; Mills, R.; Hudson, J. E.

10.1101/2024.07.01.601625 — cell biology — Posted on 2024-07-03

4723 TORC1-containing signaling endosomes source membrane from vacuoles

Muneshige, K.; Hatakeyama, R.

10.1101/2024.07.02.601695 — cell biology — Posted on 2024-07-03

4724 Laminar endocytic machinery revealed by quantitative multiplexed super-resolution imaging

Kiuchi, T.; Kobayashi, R.; Ogawa, S.; Elverston, L. L.; Watanabe, N.

10.1101/2024.07.02.601646 — cell biology — Posted on 2024-07-03

4725 Kingdom-specific lipid unsaturation shapes up sequence evolution in membrane arm subunits of eukaryotic respiratory complexes

Gupta, P.; Chakroborty, S.; Rathod, A. K.; Bhat, S.; Ghosh, S.; Rao T., P.; Nagaraj, R.; Manna, M.; Raychaudhuri, S.

10.1101/2024.07.01.601479 — cell biology — Posted on 2024-07-03

4726 De novo cancer mutations frequently associate with recurrent chromosomal abnormalities during long-term human pluripotent stem cell culture

Al Delbany, D.; Ghosh, M. S.; Krivec, N.; Huyghebaert, A. E.; Regin, M.; Duong, C. M.; Lei, Y.; Sermon, K. D.; Olsen, C.; Spits, C.

10.1101/2024.07.01.601640 — cell biology — Posted on 2024-07-03

4727 Enhancing reproducibility and decentralization in single cell research with biocytometry

Fikar, P.; Alvarez, L.; Berne, L.; Cienciala, M.; Kan, C.; Kasl, H.; Luo, M.; Novackova, Z.; Ordonez, S.; Sramkova, Z.; Holubova, M.; Lysak, D.; Avery, L.; Caro, A. A.; Crowder, R. N.; Diaz-Martinez, L. A.; Donley, D. W.; Giorno, R. R.; Reed, I. K. G.; Hensley, L. L.; Johnson, K. C.; Kim, P.; Kim, A. Y.; LaGier, A. J.; Newman, J. J.; Padilla-Crespo, E.; Reyna, N. S.; Tsotakos, N.; Al-Saadi, N. N.; Appleton, T.; Arosemena-Pickett, A.; Bell, B. A.; Bing, G.; Bishop, B.; Forde, C.; Foster, M. J.; Gray, K.; Hasley, B. L.; Johnson, K.; Jones, D. J.; LaShall, A. C.; McGuire, K.; McNaughton, N.; Morg

10.1101/2024.07.01.601489 — cell biology — Posted on 2024-07-03

4728 Coherent Raman microscopy detects nucleolar defects through amide I peak shifts originating from b-sheets: an application to visualizing ongoing cellular senescence

Ishibashi, S.; Inoko, A.; Oka, Y.; Leproux, P.; Kano, H.

10.1101/2024.07.01.600896 — cell biology — Posted on 2024-07-03

4729 Polyamines regulate cell fate by altering the activity of histone-modifying enzymes

Emmons-Bell, M.; Forsyth, G.; Sundquist, A.; Oldeman, S.; Gardikioti, A.; de Souza, R.; Coene, J.; Kamel, M.; Ayyappan, S.; Fuchs, H. A.; Verhelst, S.; Smeeton, J.; Musselman, C. A.; Schvartzman, J. M.

10.1101/2024.07.02.600738 — cell biology — Posted on 2024-07-03

4730 Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis

Hadefi, A.; Leprovots, M.; Dinsart, G.; Marefati, M.; Vermeersch, M.; Monteyne, D.; Perez-Morga, D.; Lefort, A.; Libert, F.; Verset, L.; Liefferinckx, C.; Moreno, C.; Jacques, D.; Trepo, E.; Garcia, M.-I.

10.1101/2024.07.02.601648 — cell biology — Posted on 2024-07-03

4731 The microcephaly protein WDR62 regulates cellular purine metabolism through the HSP70/HSP90 chaperone machinery.

Morris, M. J.; Yeap, Y. Y. C.; Chen, C.; Millard, S. S.; Pagan, J. K.; Ng, D. C. H.

10.1101/2024.07.01.601630 — cell biology — Posted on 2024-07-03

4732 APCCdh1-mediated degradation of Cdh1 is necessary for faithful meiotic chromosome segregation in S. cerevisiae

Ostapenko, D.; Solomon, M. J.

10.1101/2024.07.01.601619 — cell biology — Posted on 2024-07-03

4733 Large transient assemblies of Apaf1 constitute the apoptosome in cells

Borgeaud, A. C.; Ganeva, I.; Klein, C.; Stooss, A.; Ross-Kaschitza, D.; Wu, L.; Riley, J. S.; Tait, S. W.; Lemmin, T.; Kaufmann, T.; Kukulski, W.

10.1101/2024.07.01.600688 — cell biology — Posted on 2024-07-03

4734 Dsg2 truncation causes a lethal barrier breakdown in mice

Kugelmann, D.; Butz, E. S.; Garcia Ponce, A.; Radeva, M. Y.; Neubauer, J.; Hiermaier, M.; Siadjeu, C.; Burkard, N.; Egu, D.; Horn, A. K. E.; Schmitz, C.; Vuopala, K. S.; Kuismin, O.; Schlegel, N.; Waschke, J.

10.1101/2024.07.01.601522 — cell biology — Posted on 2024-07-03

4735 Comparison of Conventional Cytomorphology, Automated Cell Counting, and FTIR Spectroscopy for Detection of CNS Involvement in Acute Leukaemia

esohe, l. a.; ADEGBE, S.

10.1101/2024.07.01.601535 — cell biology — Posted on 2024-07-03

4736 Staphylococcal sRNA IsrR down-regulates methylthiotransferase MiaB under iron-deficient conditions

Barrault, M.; Leclair, E.; Kumeko, E. K.; Jacquet, E.; Bouloc, P.

10.1101/2023.11.09.566390 — microbiology — Posted on 2024-07-03

4737 THE DUAL-SPECIFICITY KINASE DYRK1A INTERACTS WITH THE HEPATITIS B VIRUS GENOME AND REGULATES THE PRODUCTION OF VIRAL RNA

Pastor, F.; Charles, E.; Di Vona, C.; Chapelle, M.; Rivoire, M.; Passot, G.; Chabot, B.; de la Luna, S.; Lucifora, J.; Durantel, D.; Salvetti, A.

10.1101/2024.05.30.596758 — microbiology — Posted on 2024-07-03

4738 NE contribution to rebooting unconsciousness caused by midazolam

Gu, L.; Shao, W.; Liu, L.; Xu, Q.; Wang, Y.; Gu, J.; Yang, Y.; Zhang, Z.; Wu, Y.; Shen, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, Y.; Zhang, H.

10.1101/2023.03.20.533578 — neuroscience — Posted on 2024-07-03

4739 Reversible ubiquitination of integrated domain controls paired NLR immune receptor complex homeostasis

Chen, Z.; Huang, J.-h.; Li, J.; Menke, F.; Jones, J. D.; Guo, H.

10.1101/2024.07.01.599856 — plant biology — Posted on 2024-07-03

4740 Rational Design of Frontline Institutional Phage Cocktail for the Treatment of Nosocomial Enterobacter cloacae Complex Infections

Subedi, D.; Gordillo Altamirano, F. L.; Deehan, R.; Perera, A.; Patwa, R.; Kostoulias, X.; Korneev, D.; Blakeway, L.; Macesic, N.; Peleg, A. Y. L.; Barr, J. J.

10.1101/2024.06.30.601436 — microbiology — Posted on 2024-07-03

4741 Podoplanin Positive Cell-derived Extracellular Vesicles Contribute to Cardiac Amyloidosis After Myocardial Infarction

Kishore, R.; Cimini, M.; Hansmann, U. H. E.; Gonzalez, C.; Chesney, A. D.; Trungcao, M.; Gao, E.; Wang, T.; Roy, R.; Forte, E.; Mallaredy, V.; Gurrala, C. T.; Magadum, A.; Joladarashi, D.; Benedict, C. L.; Koch, W.; Tükel, C.

10.1101/2024.06.28.601297 — immunology — Posted on 2024-07-03

4742 Neonatal sensitivity to vocal emotions: A developmental change at 37 weeks of gestational age

Hou, X.; Zhang, P.; Mo, L.; Peng, C.; Zhang, D.

10.1101/2024.01.14.575448 — neuroscience — Posted on 2024-07-03

4743 Functions of Direct and Indirect Pathways for Action Selection Are Quantitatively Analyzed in A Spiking Neural Network of The Basal Ganglia

Kim, S.-Y.; Lim, W.

10.1101/2024.04.21.590492 — neuroscience — Posted on 2024-07-03

4744 Enhanced purinergic signaling in the paraventricular hypothalamus induces hyperphagic obesity and insulin resistance

Liu, Y.; Zhang, H.; Zhang, Q.; Najam, S. S.; Liang, X.; Sirakawin, C.; Lin, D.; Huang, S.; Bondarenko, A.; Konopka, W.; Zhang, Y.; Zhang, Z.; Wu, S.; Jing, M.; Vinnikov, I. A.

10.1101/2024.07.02.601503 — neuroscience — Posted on 2024-07-03

4745 Sex-specific loss of mitochondrial membrane integrity and mass in the auditory brainstem of a mouse model of Fragile X syndrome

Caron, C.; McCullagh, E. A.; Bertolin, G.

10.1101/2024.07.02.601649 — neuroscience — Posted on 2024-07-03

4746 A 3.5-minute-long reading-based fMRI localizer for the language network

Tuckute, G.; Lee, E. J.; Sathe, A.; Fedorenko, E.

10.1101/2024.07.02.601683 — neuroscience — Posted on 2024-07-03

4747 Transdiagnostic Neurobiology of Social Cognition and Individual Variability as Measured by Fractional Amplitude of Low-Frequency Fluctuation in Schizophrenia and Autism Spectrum Disorders

Bagheri, S.; Yu, J.-C.; Gallucci, J.; Tan, V.; Oliver, L. D.; Dickie, E. W.; Rashidi, A. G.; Foussias, G.; Lai, M.-C.; Buchanan, R. W.; Malhotra, A. K.; Voineskos, A. N.; Ameis, S. H.; Hawco, C.

10.1101/2024.07.02.601737 — neuroscience — Posted on 2024-07-03

4748 Neuronal APOE4-induced Early Hippocampal Network Hyperexcitability in Alzheimers Disease Pathogenesis

Tabuena, D. R.; Jang, S.-S.; Grone, B.; Yip, O.; Aery Jones, E. A.; Blumenfeld, J.; Liang, Z.; Koutsodendris, N.; Rao, A.; Ding, L.; Zhang, A. R.; Hao, Y.; Xu, Q.; Yoon, S. Y.; De Leon, S.; Huang, Y.; Zilberter, M.

10.1101/2023.08.28.555153 — neuroscience — Posted on 2024-07-03

4749 Allometric scaling of somatic mutation and epimutation rates in trees

Johannes, F.

10.1101/2024.07.01.601331 — evolutionary biology — Posted on 2024-07-02

4750 tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa

Sun, J.; Wu, J.; Yuan, Y.; Fan, L.; Chua, W. L. P.; Ling, Y. H. S.; Balamkundu, S.; Dwijapriya, D.; Suen Suen, H. C.; de Crecy-Lagard, V.; Dziergowska, A.; Dedon, P.

10.1101/2024.07.01.601603 — genetics — Posted on 2024-07-02

4751 Comparative Transcriptomics of Arabidopsis, Medicago, Brachypodium and Setaria species during Phosphorus limitation

Pant, P.; Duan, H.; Krom, N.; Scheible, W.-R.

10.1101/2024.07.02.601706 — molecular biology — Posted on 2024-07-02

4752 R(+) Propranolol decreases lipid accumulation in hemangioma-derived stem cells

Tan, J. W. H.; Wylie-Sears, J.; Seebauer, C.; Mulliken, J. B.; Francois, M.; Holm, A.; Bischoff, J.

10.1101/2024.07.01.601621 — molecular biology — Posted on 2024-07-02

4753 Delineation of a thrombin receptor-stimulated vascular smooth muscle cell transition generating cells in the plaque-stabilising fibrous cap

Taylor, J. C.; Worssam, M.; Oc, S.; Lambert, J.; Mahbubani, K. T.; Foote, K.; Finigan, A.; Chan, Y.-H.; Figg, N.; Clarke, M. C.; Bennett, M. R.; Jorgensen, H. F.

10.1101/2024.07.02.600985 — molecular biology — Posted on 2024-07-02

4754 Polyunsaturated Fatty Acid - mediated Cellular Rejuvenation for Reversing Age-related Vision Decline

Gao, F.; Tom, E.; Rydz, C.; Cho, W.; Kolesnikov, A. V.; Sha, Y.; Papadam, A.; Jafari, S.; Joseph, A. P.; Ahanchi, A.; Balalaei Someh Saraei, N.; Lyon, D. C.; Foik, A. T.; Nie, Q.; Grassmann, F.; Kefalov, V.; Skowronska-Krawczyk, D.

10.1101/2024.07.01.601592 — molecular biology — Posted on 2024-07-02

4755 Establishing a co-culture aggregate of N-cycle bacteria to elucidate flocculation in biological wastewater treatment

Parret, L.; Simoens, K.; Horemans, B.; De Vrieze, J.; Smets, I.

10.1101/2024.07.02.601720 — microbiology — Posted on 2024-07-02

4756 Genetic hypogonadal (Gnrh1 hpg) mouse model uncovers influence of reproductive axis on maturation of the gut microbiome during puberty

Sisk-Hackworth, L. G.; Akhavan, S. R.; Krutkin, D. D.; Kelley, S. T.; Thackray, V. G.

10.1101/2024.07.01.601610 — microbiology — Posted on 2024-07-02

4757 Mobile Integrons Encode Phage Defence Systems

Kieffer, N.; Hipolito, A.; Blanco, P.; Delobelle, T.; Ojeda, F. M.; Jove, T.; Jurenas, D.; Garcia-Quintanilla, M.; Domingo-Calap, P.; Escudero, J. A.

10.1101/2024.07.02.601719 — microbiology — Posted on 2024-07-02

4758 Nitrogen Availability and Utilisation of Oligopeptides by Yeast in Industrial Scotch Grain Whisky Fermentation

Berg, H. Y.; Arju, G.; Nisamedtinov, I.

10.1101/2024.07.02.601656 — microbiology — Posted on 2024-07-02

4759 Functional analysis of ESRP1/2 gene variants and CTNND1 isoforms in orofacial cleft pathogenesis

Caetano da Silva, C.; Macias Trevino, C.; Mitchell, J.; Murali, H.; Tsimbal, C.; Dalessandro, E.; Carroll, S. H.; Kochhar, S.; Curtis, S. W.; Cheng, C. H. E.; Wang, F.; Kutschera, E.; Carstens, R. P.; Xing, Y.; Wang, K.; Leslie, E. J.; Liao, E. C.

10.1101/2024.07.02.601574 — genetics — Posted on 2024-07-02

4760 Cytosolic N6AMT1-dependent translation supports mitochondrial RNA processing

Foged, M. M.; Recazens, E.; Chollet, S.; Lisci, M.; Allen, G. E.; Zinshteyn, B.; Boutguetait, D.; Munch, C. A.; Mootha, V. K.; Jourdain, A. A.

10.1101/2024.07.02.601698 — molecular biology — Posted on 2024-07-02

4761 Enhancer-promoter hubs organize transcriptional networks promoting oncogenesis and drug resistance

Perlman, B. S.; Burget, N.; Zhou, Y.; Schwartz, G. W.; Petrovic, J.; Modrusan, Z.; Faryabi, R. B.

10.1101/2024.07.02.601745 — molecular biology — Posted on 2024-07-02

4762 Progerin Can Induce DNA Damage in the Absence of Global Changes in Replication or Cell Proliferation

Joudeh, L. A.; Schuck, P. L.; Van, N. M.; DiCintio, A. J.; Stewart, J. A.; Waldman, A. S.

10.1101/2024.07.02.601729 — molecular biology — Posted on 2024-07-02

4763 A two-component signature determines which rust fungi secreted proteins are translocated into the cells of the host plant

Lawrence, G. J.

10.1101/2024.07.01.601607 — molecular biology — Posted on 2024-07-02

4764 Role of vaccinia virus growth factor in stimulating the mTORC1-CAD axis of the de novo pyrimidine pathway under different nutritional cues

Dsouza, L.; Pant, A.; Pope, B.; Yang, Z.

10.1101/2024.07.02.601567 — microbiology — Posted on 2024-07-02

4765 Plasmids modulate microindel mutations in Acinetobacter baylyi ADP1

Liljegren, M. M.; Gama, J. A.; Johnsen, P. J.; Harms, K.

10.1101/2024.07.02.601687 — microbiology — Posted on 2024-07-02

4766 PhoPQ-mediated lipopolysaccharide modification regulates intrinsic resistance to tetracycline and glycylcycline antibiotics in Escherichia coli

Lee, C.-R.; Choi, B. J.; Choi, U.; Ryu, D.-B.

10.1101/2024.07.01.601565 — microbiology — Posted on 2024-07-02

4767 Eco-Microbiology: Discovering Biochemical Enhancers of PET Biodegradation by Piscinibacter sakaiensis

Piedra, F.-A.; Salazar, M. A.; Rahman, R.; Clark, J. R.; Maresso, A. W.

10.1101/2024.07.01.601593 — microbiology — Posted on 2024-07-02

4768 Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery anddelivery of novel cargoes to the Mtb surface

Lepe, B. A.; Zheng, C. R.; Leddy, O. K.; Allsup, B. L.; Solomon, S. L.; Bryson, B. D.

10.1101/2024.07.02.601718 — microbiology — Posted on 2024-07-02

4769 The Ex Vivo Infection of the Peripheral Bovine Mononuclear Cells (PBMCs) and the Bovine Spleen Cells with the Bovine Coronavirus (BCoV) Induced a Differential Expression of the Host Cytokine Genes Profiles and Modulates the Virus Replication

Shah, A. U.; Hemida, M. H.

10.1101/2024.07.01.601600 — microbiology — Posted on 2024-07-02

4770 Myoferlin is an essential component of late-stage vRNP trafficking vesicles for enveloped RNA viruses.

Bonazza, S.; Turkington, H. L.; Coutts, H. L.; Sukumar, S.; Hawthorn, C.; Getty, E. M. P. E.; Touzelet, O.; Barabas, J.; Power, U.; Courtney, D. G.

10.1101/2024.07.02.601679 — microbiology — Posted on 2024-07-02

4771 Antagonistic effects of actin-specific toxins on Salmonella Typhimurium invasion into mammalian cells

Heisler, D. B.; Kudryashova, E.; Hitt, R.; Williams, B.; Dziejman, M.; Gunn, J. S.; KUDRYASHOV, D. S.

10.1101/2024.07.01.601609 — microbiology — Posted on 2024-07-02

4772 Single-cell transcriptomics highlights sexual cues among reproductive life stages of uncultivated Acantharia (Radiolaria)

Rizos, I.; Romac, S.; Juery, C.; Berthelier, C.; Decelle, J.; Bernardes, J.; Corre, E.; Bittner, L.; Not, F.

10.1101/2024.07.02.601653 — microbiology — Posted on 2024-07-02

4773 Identifying Genetic Variations in emm89 Streptococcus pyogenes Linked to Severe Invasive Infections

Ono, M.; Yamaguchi, M.; Motooka, D.; Hirose, Y.; Higashi, K.; Sumitomo, T.; Miyoshi-Akiyama, T.; Okuno, R.; Yamaguchi, T.; Kawahara, R.; Otsuka, H.; Nakanishi, N.; Kazawa, Y.; Nakagawa, C.; Yamaguchi, R.; Sakai, H.; Matsumoto, Y.; Ikebe, T.; Kawabata, S.

10.1101/2024.07.02.601674 — microbiology — Posted on 2024-07-02

4774 HIV-1 control in vivo is related to the number but not the fraction of infected cells with viral unspliced RNA

Capoferri, A. A.; Wiegand, A.; Hong, F.; Jacobs, J. L.; Spindler, J.; Musick, A.; Bale, M. J.; Shao, W.; Sobolewski, M. D.; Cillo, A. R.; Luke, B. T.; Fennessey, C. M.; Gorelick, R. J.; Hoh, R.; Halvas, E. K.; Deeks, S. G.; Coffin, J. M.; Mellors, J. W.; Kearney, M. F.

10.1101/2024.07.01.601579 — microbiology — Posted on 2024-07-02

4775 Network architecture of transcriptomic stress responses in zebrafish embryos

Beine, K.; Feugere, L.; Turner, A.; Wollenberg Valero, K. C.

10.1101/2024.06.30.601387 — systems biology — Posted on 2024-07-02

4776 Biochemical implementation of acceleration sensing and PIDA control

Alexis, E.; Espinel-Rios, S.; Kevrekidis, I. G.; Avalos, J. L.

10.1101/2024.07.02.601775 — synthetic biology — Posted on 2024-07-02

4777 Enzyme-Responsive DNA Condensates

Bucci, J.; Malouf, L.; Tanase, D. A.; Farag, N.; Lamb, J. R.; Gentile, S.; Del Grosso, E.; Kaminski, C. F.; Di Michele, L.; Ricci, F.

10.1101/2024.07.02.601714 — synthetic biology — Posted on 2024-07-02

4778 Temporal Image Sandwiches Enable Link between Functional Data Analysis and Deep Learning for Single-Plant Cotton Senescence

DeSalvio, A. J.; Adak, A.; Arik, M. A.; Shepard, N. R.; DeSalvio, S. M.; Murray, S. C.; Garcia-Ramos, O.; Badavath, H.; Stelly, D. M.

10.1101/2024.06.30.601428 — plant biology — Posted on 2024-07-02

4779 Harnessing CRISPR/Cas12a Technology to Combat Wheat Dwarf Virus Without Genetic Modification

Baran, B.; Teymur, T.; Morca, A. F.; Konuk, M.; Tastan, C.

10.1101/2024.07.01.598556 — plant biology — Posted on 2024-07-02

4780 MetaGXplore: Integrating Multi-Omics Data with Graph Convolutional Networks for Pan-cancer Patient Metastasis Identification

Jiang, T.; Jiang, H.; Ma, X.; Xu, M.; Zhang, W.

10.1101/2024.06.30.601445 — bioinformatics — Posted on 2024-07-02

4781 Drought tolerance as an evolutionary precursor to frost and winter tolerance in grasses

Schat, L.; Schubert, M.; Fjellheim, S.; Humphreys, A. M.

10.1101/2024.06.29.601311 — evolutionary biology — Posted on 2024-07-02

4782 Stepwise developmental mimicry generates proximal-biased kidney organoids

Schnell, J.; Miao, Z.; Achieng, M.; Fausto, C. C.; Wang, V.; De Kuyper, F.; Thornton, M. E.; Grubbs, B.; Kim, J.; Lindstrom, N. O.

10.1101/2024.06.28.601028 — developmental biology — Posted on 2024-07-02

4783 IgM plays a prominent role in naturally acquired immunity against Plasmodium falciparum gametocytes

Chan, J.-A.; Lisboa-Pinto, A.; Lu, S.; Harris, A.; Dixon, M. W.; Thomas, A.; Drew, D. R.; Jayakrishnan, N.; Larcher, K.; Naghizadeh, M.; Opi, D. H.; Reiling, L.; Theisen, M.; Chelimo, K.; Kaius-Ome, M.; Mantila, D.; Laman, M.; Robinson, L.; Mueller, I.; King, C. L.; Dent, A.; Kazura, J.; Beeson, J.

10.1101/2024.06.30.601434 — immunology — Posted on 2024-07-02

4784 Self-organizing recruitment of compensatory areas maximizes residual motor performance post-stroke

Lee, K.; Barradas, V. R.; Schweighofer, N.

10.1101/2024.06.28.601213 — neuroscience — Posted on 2024-07-02

4785 Myelin-informed forward models for M/EEG source reconstruction

Helbling, S.; Meyer, S. S.; Weiskopf, N.

10.1101/2024.06.30.601378 — neuroscience — Posted on 2024-07-02

4786 TGFb-ANGPT2-Tie2 axis in cancer-associated fibroblasts reprograms oral cancer cells to embryonic-like cell state with predictive significance of poor prognosis

Mitra, P.; Saha, U.; Stephen, K. J.; Prasad, P.; Patel, A. K.; Harshvardhan, B. V.; Mondal, S. K.; Kurkalang, S.; Roy, S.; Ghosh, A.; Roy, S. S.; DasSarma, J.; Biswas, N. K.; Acharya, M.; Sharan, R.; Arun, P.; Jolly, M. K.; Maitra, A.; Singh, S.

10.1101/2024.06.29.601319 — cancer biology — Posted on 2024-07-02

4787 Exploring individual codon influence on protein expression: a predictive approach

Zaytsev, K.; Bogatyreva, N. S.; Fedorov, A. N.

10.1101/2024.06.30.601029 — bioinformatics — Posted on 2024-07-02

4788 GeneLLM: A Large cfRNA Language Model for Cancer Screening from Raw Reads

Deng, S.; Sha, L.; Jin, Y.; Zhou, T.; Wang, C.; Liu, Q.; Guo, H.; Xiong, C.; Xue, Y.; Li, X.; Li, Y.; Gao, Y.; Hong, M.; Xu, J.; Chen, S.; Wang, P.

10.1101/2024.06.29.601341 — bioinformatics — Posted on 2024-07-02

4789 Prognostic Significance of Potential Target Networks and P16INK4a In Early Diagnosis of Non-Small Cell Lung Cancer

Kundadka, V.; Vatsa, R.; Kaur, N.

10.1101/2024.06.28.600894 — bioinformatics — Posted on 2024-07-02

4790 High-Throughput Bioprinting of Spheroids for Scalable Tissue Fabrication

Kim, M. H.; Singh, Y. P.; Celik, N.; Yeo, M.; Rizk, E.; Hayes, D. J.; Ozbolat, I. T.

10.1101/2024.06.30.601432 — bioengineering — Posted on 2024-07-02

4791 A new yeast-based bioreporter for simple, sensitive, and cost-effective detection of dioxin-like compounds

Liang, Y.; Liu, H.; Wang, L.; Zhao, J.; Li, S.; Yi, L.; Jiang, S.; Lu, Z.; Zhang, G.

10.1101/2024.06.30.601204 — bioengineering — Posted on 2024-07-02

4792 Measurement of covalent bond formation in light-curing hydrogels predicts physical stability under flow

Zatorski, J. M.; Lee, I. L.; Ortiz-Cardenas, J. E.; Ellena, J. F.; Pompano, R. R.

10.1101/2024.06.30.601353 — bioengineering — Posted on 2024-07-02

4793 A smartphone-based genetically recombinant whole-cell biosensor for highly sensitive monitoring of polychlorinated biphenyls (PCBs)

Luo, Q.; Zhang, F.; Zhang, M.; Hu, S.; Li, X.; Pan, L.; Lu, Z.; Wu, P.; Zhang, G.

10.1101/2024.06.28.601110 — bioengineering — Posted on 2024-07-02

4794 Hierarchical population genetic structure and signatures of adaptation in Lates calcarifer

Campbell, M. A.; Becker, J. A.

10.1101/2024.06.30.600906 — genetics — Posted on 2024-07-02

4795 Modeling Mountain Pine Beetle Abundance and Distribution in a Changing Climate

Xie, X.; Brush, M.; Lewis, M. A.

10.1101/2024.06.28.601294 — ecology — Posted on 2024-07-02

4796 Integrin-deficient T cell leukemia accumulates in the central nervous system

Lux, S. Y.; Chen, C.; Subhan, B. S.; Okuniewska, M.; Chung, H.; Vernejoul, J. B.; Martin, K. A.; Caslin, A. Y.; Schiavo, J. K.; Froemke, R.; Cammer, M.; Schwab, S. R.

10.1101/2024.06.28.601274 — immunology — Posted on 2024-07-02

4797 CREB determines the expression of ST2 in Tregs and mediates the balance between type 1 and type 2 immune responses

Hebbar Subramanyam, S.; Hriczko, J.; Look, T.; Goodarzi, T.; Clarner, T.; Verjans, E.; Boell, S.; Neullens, C.; Costa, I.; Gan, L.; Denecke, B.; Schippers, A.; Floess, S.; Huehn, J.; Schmitt, E.; Bopp, T.; Wasmuth, H.; Winograd, R.; Beyaert, R.; Lambrecht, B.; Boor, P.; Zenke, M.; Wagner, N.; Ohl, K.; Tenbrock, K.

10.1101/2024.06.29.601312 — immunology — Posted on 2024-07-02

4798 Responses to visual motion of neurons in the extrastriate visual cortex of macaque monkeys with experimental amblyopia

Van Grootel, T. J.; Raghavan, R. T.; Kelly, J. G.; Movshon, J. A.; Kiorpes, L.

10.1101/2024.07.01.601564 — neuroscience — Posted on 2024-07-02

4799 Critical roles of ERK and Akt signaling in metabolically dependent memory formation in Drosophila larvae.

Franz, H. R.; Widmann, A.

10.1101/2024.06.28.601201 — neuroscience — Posted on 2024-07-02

4800 Anatomical and functional analysis of the corticospinal tract in an FRDA mouse model

Nishiyama, M.; Kalambogias, J.; Imai, F.; Yang, E.; Lang, S.; de Nooij, J. C.; Yoshida, Y.

10.1101/2024.06.28.601178 — neuroscience — Posted on 2024-07-02

4801 Towards a simplified model of primary visual cortex

Du, F.; Nunez-Ochoa, M. A.; Pachitariu, M.; Stringer, C.

10.1101/2024.06.30.601394 — neuroscience — Posted on 2024-07-02

4802 Rod-shaped microglia interact with neuronal dendrites to regulate cortical excitability in TDP-43 related neurodegeneration

Xie, M.; Miller, A.; Pallegar, P.; Umpierre, A.; Liang, Y.; Wang, N.; Zhang, S.; Nagaraj, N.; Zachary, F.; Qi, F.; Ghayal, N.; Oskarsson, B.; Zhao, S.; Zheng, J.; Nguyen, A.; Dickson, D. W.; Wu, L.-J.

10.1101/2024.06.30.601396 — neuroscience — Posted on 2024-07-02

4803 Cerebral Microvascular Density, Permeability of the Blood-Brain Barrier, and Neuroinflammatory Responses Indicate Early Aging Characteristics in a Marfan Syndrome Mouse Model

Curry-Koski, T.; Curtin, L.; Esfandiarei, M.; Thomas, T. C.

10.1101/2024.06.30.601409 — neuroscience — Posted on 2024-07-02

4804 Axonal Tau sorting depends on the PRR2 domain and 0N4R-specific interactions hint at distinct roles of Tau isoforms in synaptic plasticity

Bell-Simons, M.; Buchholz, S.; Klimek, J.; Zempel, H.

10.1101/2024.06.28.601286 — neuroscience — Posted on 2024-07-02

4805 Mixed recurrent connectivity architecture in primate prefrontal cortex

Sigalas, E.; Libedinsky, C.

10.1101/2024.06.30.601443 — neuroscience — Posted on 2024-07-02

4806 Predicting the physiological effects of multiple drugs using electronic health record

Jeon, J.; Hong, E.; Kim, J.-Y.; Lee, S.; Kim, H. U.

10.1101/2024.06.30.601402 — systems biology — Posted on 2024-07-02

4807 Knock out of the intracellular calcium conducting ion channel Mitsugumin 23 (MG23) protects against pressure overload induced left ventricular hypertrophy and cardiac dysfunction.

Dorward, A. M.; Robertson, G. B.; Sneddon, C.; O'Rourke, C. L.; Um, I. H.; Harrison, D. J.; Nishi, M.; Takeshima, H.; Murdoch, C.; Pitt, S. J.

10.1101/2024.06.28.601299 — physiology — Posted on 2024-07-02

4808 Integrative Imaging of Lung Micro Structure: Amplifying Classical Histology by Paraffin Block μCT and same-slide Scanning Electron Microscopy

Reiser, J.; Albers, J.; Svetlove, A.; Mertiny, M.; Kommoss, F. K.; Schwab, C.; Schneemann, A.; Tromba, G.; Wacker, I.; Curticean, R. E.; Schroeder, R. R.; Kauczor, H.-U.; Wielpuetz, M. O.; Dullin, C.; Wagner, W. L.

10.1101/2024.06.29.601332 — pathology — Posted on 2024-07-02

4809 Devonian stromatoporoid historical collections in the Natural History Museum, London (UK): redescription, taxonomic revision and implications for stromatoporoid global paleobiogeography

Huang, J.; Sendino, C.; Kershaw, S.

10.1101/2024.06.30.601411 — paleontology — Posted on 2024-07-02

4810 Oscillatory Hypoxia Induced Unfolded Protein Folding Response Gene Expression Predicts Low Survival in Human Breast Cancer Patients

Suhail, Y.; Liu, Y.; Du, W.; Afzal, J.; Atiq, A.; Vera-Licona, P.; Agmon, E.; Kshitiz,

10.1101/2024.01.25.577274 — cancer biology — Posted on 2024-07-02

4811 Identification of cuproptosis and ferroptosis-related subtypes and development of a prognostic signature in colon cancer

He, Y.; Liu, F.; Jiang, Z.

10.1101/2024.06.30.601455 — bioinformatics — Posted on 2024-07-02

4812 SPACEc: A Streamlined, Interactive Python Workflow for Multiplexed Image Processing and Analysis

Tan, Y.; Kempchen, T. N.; Becker, M.; Haist, M.; Feyaerts, D.; Xiao, Y.; Su, G.; Rech, A. J.; Fan, R.; Hickey, J. W.; Nolan, G. P.

10.1101/2024.06.29.601349 — bioinformatics — Posted on 2024-07-02

4813 PRISM: Multiplexed Profiling of RNA In-Situ through Single-round of Imaging in Three-Dimensional Tissue

Chang, T.; Zhao, S.; Deng, K.; Liao, Z.; Tang, M.; Zhu, Y.; Han, W.; Yu, C.; Fan, W.; Jiang, M.; Wang, G.; Liu, D.; Peng, J.; Pang, Y.; Fei, P.; Wang, J.; Zheng, C.; Huang, Y.

10.1101/2024.06.29.601330 — bioengineering — Posted on 2024-07-02

4814 Peering into the world of wild passerines with 3D-SOCS: synchronized video capture and posture estimation

Chimento, M.; Chan, A. H. H.; Aplin, L. M.; Kano, F.

10.1101/2024.06.30.601375 — animal behavior and cognition — Posted on 2024-07-02

4815 Assessment of the transcriptional regulation of EMT and MET through accessible transposable elements

Eskier, D.; Yetkin, S.; Arslan, N.; Karakülah, G.; Alotaibi, H.

10.1101/2024.06.29.601318 — genomics — Posted on 2024-07-02

4816 Functional monocentricity with holocentric characteristics andchromosome-specific centromeres in a stick insect

Toubiana, W.; Dumas, Z.; Tran Van, P.; Parker, D. J.; Merel, V.; Schubert, V.; Aury, J.-M.; Bournonville, L.; Cruaud, C.; Houben, A.; Istace, B.; Labadie, K.; Noel, B.; Schwander, T.

10.1101/2024.06.30.601385 — evolutionary biology — Posted on 2024-07-02

4817 Selection for early reproduction leads to accelerated aging and extensive metabolic remodeling in Drosophila melanogaster populations

Hubert, D. L.; Arnold, K. R.; Greenspan, Z. G.; Pupo, A.; Robinson, R. D.; Chavarin, V. V.; Barter, T. T.; Djukovic, D.; Raftery, D.; Vue, Z.; Hinton, A.; McReynolds, M. R.; Harrison, B. R.; Phillips, M. A.

10.1101/2024.06.28.601037 — evolutionary biology — Posted on 2024-07-02

4818 Forecasting trade and biosecurity risk under climate change

Camac, J. S.; Cantele, M.; Ha Pham, V.; Li, C.; Robinson, A.; Kompas, T.

10.1101/2024.06.30.601437 — ecology — Posted on 2024-07-02

4819 Informing grassland ecosystem modeling with in-situ and remote sensing observations

Arteaga, J.; Hartman, M.; Parton, W.; Chen, M.; Gao, W.

10.1101/2024.06.28.601224 — ecology — Posted on 2024-07-02

4820 Analysing bird population trends from monitoring data with highly structured sampling designs

Rieger, M. R.; Grueneberg, C.; Oberhaus, M.; Trautmann, S.; Parepa, M.; Anthes, N.

10.1101/2024.06.30.601382 — ecology — Posted on 2024-07-02

4821 The inflammasome adaptor pycard is essential for immunity against Mycobacterium marinum infection in adult zebrafish

Uusi-Mäkelä, M.; Harjula, S.-K. E.; Junno, M.; Sillanpää, A.; Nätkin, R.; Niskanen, M. T.; Nykter, M.; Rämet, M.

10.1101/2024.06.28.601189 — immunology — Posted on 2024-07-02

4822 Autoimmunity and clinical pathology amelioration in SLE by Dexamethasone primed Mesenchymal Stem Cell derived conditioned media

priya, K.; Rawat, S.; Das, D.; Chaubey, M.; Thacker, H.; Giri, K.; Singh, S.; Rai, M.; Mohanty, S.; Rai, G.

10.1101/2024.06.29.601320 — immunology — Posted on 2024-07-02

4823 Single cell transcriptome profiling reveals pathogenesis of Bullous Pemphigoid

Wang, Y.; Liang, G.; Zhao, C.; Wei, Q.; Feng, S.

10.1101/2024.06.28.601141 — immunology — Posted on 2024-07-02

4824 Assessing data quality on fetal brain MRI reconstruction: a multi-site and multi-rater study

Sanchez, T.; Mihailov, A.; Gomez, Y.; Marti-Juan, G.; Eixarch, E.; Jakab, A.; Dunet, V.; Koob, M.; Auzias, G.; Bach Cuadra, M.

10.1101/2024.06.28.601169 — neuroscience — Posted on 2024-07-02

4825 The Surgical Method of Craniectomy Differentially Affects Acute Seizures, Brain Deformation and Behavior in a TBI Animal Model

Santana-Gomez, C. E. E.; Smith, G.; Mousavi, A.; Shamas, M.; Harris, N. G.; Staba, R.

10.1101/2024.06.28.601257 — neuroscience — Posted on 2024-07-02

4826 Layer-specific reorganization of mnemonic representations in primate retrosplenial cortex during learning

KAMBI, N. A.; Afrasiabi, M. A.; Phillips, J. M.; Kenchappa, S. C.; Cleveland, D.; Redinbaugh, M. J.; Mohanta, S.; Wang, B.; Fayyad, M.; Saalmann, Y. B.

10.1101/2024.06.30.601381 — neuroscience — Posted on 2024-07-02

4827 Modular organization of synapses within a neuromere for distinct axial locomotion in Drosophila larvae

Fukumasu, K.; Nose, A.; Kohsaka, H.

10.1101/2024.06.29.601329 — neuroscience — Posted on 2024-07-02

4828 Frontal-posterior loop integrating captured attention into visual consciousness in the human brain

Zhang, X.; Zhang, C.; Guo, Z.; Wu, X.; Jiang, Y.; Zhang, K.; Wang, L.

10.1101/2024.06.30.601105 — neuroscience — Posted on 2024-07-02

4829 Nucleus accumbens sub-regions experience distinct dopamine release responses following acute and chronic morphine exposure

Gooding, S. W.; Lewis, E.; Chau, C.; Sandhu, S.; Glienke, J.; Whistler, J.

10.1101/2024.06.28.601282 — neuroscience — Posted on 2024-07-02

4830 A high-throughput approach for the efficient prediction of perceived similarity of natural objects

Kaniuth, P.; Mahner, F. P.; Perkuhn, J.; Hebart, M. N.

10.1101/2024.06.28.601184 — neuroscience — Posted on 2024-07-02

4831 NREM sleep brain networks modulate cognitive recovery from sleep deprivation

Lee, K.; Wang, Y.; Cross, N.; Jegou, A.; Razavipour, F.; Pomares, F. B.; Perrault, A. A.; Nguyen, A.; Aydin, U.; Uji, M.; Abdallah, C.; Anticevic, A.; Frauscher, B.; Benali, H.; Dang-vu, T. T.; Grova, C.

10.1101/2024.06.28.601285 — neuroscience — Posted on 2024-07-02

4832 Spatial transcriptomics reveals influence of microenvironment on intrinsic fates in melanoma therapy resistance

Boe, R. H.; Triandafillou, C. G.; Lazcano, R.; Wargo, J. A.; Raj, A.

10.1101/2024.06.30.601416 — systems biology — Posted on 2024-07-02

4833 Temporally resolved growth patterns reveal novel information about the polygenic nature of complex quantitative traits

Sweet, D.; Tirado, S.; Cooper, J.; Springer, N. M.; Hirsch, C. D.; Hirsch, C.

10.1101/2024.06.29.601327 — plant biology — Posted on 2024-07-02

4834 Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome

Carlein, C.; Hoffmann, M. D.; Amaral, A. G.; Bickelmann, C.; Lotfinia, A.; de Selliers, L.-A.; Audouze-Chaud, J.; Wrublewsky, S.; Lauterbach, M. A.; von der Malsburg, K.; van der Laan, M.; Bozem, M.; Hoth, M.; Gilon, P.; Ravier, M.; Morgan, B.; Ampofo, E.; Maack, C.; Prates Roma, L.

10.1101/2024.06.28.601122 — physiology — Posted on 2024-07-02

4835 Are circulating levels of the myokine irisin linked to type 2 diabetes? A systematic review and meta-analysis

Aminov, E.; Folan, P.; Pisconti, A.

10.1101/2024.06.29.601052 — physiology — Posted on 2024-07-02

4836 The oncofetal protein IMP1 regulates the transcriptomic landscape to drive early events in pancreatic cancer progression and growth

Hacariz, O.; Messina-Pacheco, J.; Goodfellow, E.; Leibovitch, M.; Lowy, A.; Perrino, S.; Jean-Claude, B.; Gao, Z.-H.; Gregorieff, A.; Brodt, P.

10.1101/2024.06.28.601273 — cancer biology — Posted on 2024-07-02

4837 Genomic and single-cell characterization of patient-derived tumor organoid models of head and neck squamous cell carcinoma

Um, J. H.; Zheng, Y.; Mao, Q.; Nam, C.; Zhao, H.; Koh, Y. W.; Shin, S.-J.; Park, Y. M.; Lin, D.

10.1101/2024.06.28.601068 — cancer biology — Posted on 2024-07-02

4838 FLT3 is genetically essential for ITD-mutated leukemic stem cells but dispensable for human hematopoietic stem cells

Araujo, J. L.; Wagenblast, E.; Voisin, V.; McLeod, J.; Gan, O. I.; Bansal, S.; Jin, L.; Mitchell, A.; Gratton, B.; Cutting, S.; Arruda, A.; Doedens, M.; Capo-Chichi, J.-M.; Abelson, S.; Minden, M. D.; Wang, J. C.; Sobrinho-Simoes, M. A.; Pinto-do-O, P.; Lechman, E.; Dick, J. E.

10.1101/2024.06.30.601363 — cancer biology — Posted on 2024-07-02

4839 Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic adenocarcinoma

Safari, M.; Scotto, L.; Basseville, A.; Litman, T.; Xue, H.; Petrukhin, L.; Zhou, P.; Morales, D. V.; Damoci, C.; Zhu, M.; Hull, K.; Olive, K. P.; Fojo, T.; Romo, D.; Bates, S. E.

10.1101/2024.06.30.600495 — cancer biology — Posted on 2024-07-02

4840 Cellular Dynamics Upon Immune Checkpoint Inhibition

Lin, Z.; Petrenko, E.; Chandra, M.; Srinivas, N.; Ugurel, S.; Becker, J.; Aran, D.

10.1101/2024.06.30.601413 — cancer biology — Posted on 2024-07-02

4841 Dynamic Localization of Leukemia Stem Cells via CXCL12 Regulates Leukemia Progression

Wang, C.; Pan, Y.; Dong, R.; Zhou, W.; Meng, X.; Shi, Y.; Nistala, R.; Hammer, R.; Li, L.; Kang, X.

10.1101/2024.06.29.601323 — cancer biology — Posted on 2024-07-02

4842 The Mammalian KU70 C-terminus SAP Domain Is Required to Repair Exogenous DNA Damage

Wang, Y.; Czap, M.; Kim, H.; Lu, H.; Liu, J.; Chang, Y.; Romanienko, P.; Montagna, C.; Shen, Z.

10.1101/2024.06.30.601420 — cancer biology — Posted on 2024-07-02

4843 Feeders and Expellers, Two Types of Animalcules With Outboard Cilia, Have Distinct Surface Interactions

Prakash, P.; Vona, M.; Goldstein, R. E.

10.1101/2024.06.29.601328 — biophysics — Posted on 2024-07-02

4844 StarSignDNA: Signature tracing for accurate representation of mutational processes

Bope, c. D.; Kalyanasundaram, S.; Rand, K. D.; Lingjaerde, O. C.; Hovig, E.; Nakken, S.

10.1101/2024.06.29.601345 — bioinformatics — Posted on 2024-07-02

4845 MitoStructSeg: A Comprehensive Platform for Mitochondrial Structure Segmentation and Analysis

Wang, X.; Cai, B.; Jia, Z.; Chen, Y.; Guo, S.; Liu, Z.; Wan, X.; Zhang, F.; Hu, B.

10.1101/2024.06.28.601295 — bioinformatics — Posted on 2024-07-02

4846 e3SIM: epidemiological-ecological-evolutionary simulation framework for genomic epidemiology

Xu, P.; Liang, S.; Hahn, A.; Zhao, V.; Lo, W. T. J.; Haller, B. C.; Sobkowiak, B.; Chitwood, M. H.; Colijn, C.; Cohen, T.; Rhee, K. Y.; Messer, P. W.; Wells, M. T.; Clark, A. G.; Kim, J.

10.1101/2024.06.29.601123 — bioinformatics — Posted on 2024-07-02

4847 CoPR: Collective Pattern Recognition-a Framework for Microbial Community Activity Analysis

Vidanaarachchi, R.; Tang, S.-L.; Halgamuge, S. K.

10.1101/2024.06.30.601456 — bioinformatics — Posted on 2024-07-02

4848 A graph-based practice of evaluating collective identities of cell clusters

Okano, Y.; Kase, Y.; Okano, H.

10.1101/2024.06.28.601289 — bioinformatics — Posted on 2024-07-02

4849 PIEZO1-Mediated Mechanotransduction Regulates Collagen Synthesis on Nanostructured 2D and 3D Models of Fibrosis

Rashidi, N.; Harasymowicz, N.; Savadipour, A.; Steward, N.; Tang, R.; Oswald, S.; Guilak, F.

10.1101/2024.06.30.601386 — bioengineering — Posted on 2024-07-02

4850 Polyploidy of MDA-MB-231 cells drives increased extravasation with enhanced cell-matrix adhesion

Hirose, S.; Osaki, T.; Kamm, R.

10.1101/2024.06.28.601261 — bioengineering — Posted on 2024-07-02

4851 Tracking spatial patterns and nocturnal arousal in an undisturbed natural population of the pulse-type weakly electric fish Gymnotus omarorum

Migliaro, A.; Pedraja, F.; Mucha, S.; Benda, J.; Silva, A.

10.1101/2024.06.29.600875 — animal behavior and cognition — Posted on 2024-07-02

4852 The role of LEDGF in transcription is exploited by HIV-1 to position integration

Pathak, R.; Esnault, C.; Radhakrishnan, R.; Singh, P. K.; Hongen, H.; Dale, R. K.; Anand, A.; Bedwell, G. J.; Engelman, A.; Rabi, A.; Hormoz, S.; Singh, P.; Levin, H. L.

10.1101/2024.06.29.601340 — genomics — Posted on 2024-07-02

4853 Unveiling the Family of Optimal Accelerations in Minimax Optimization and Fixed-Point Algorithms

Bartlett, P.; Li, C. J.; Wu, J.; Yu, B.

10.1101/2024.06.29.601352 — genetics — Posted on 2024-07-02

4854 Population genetic consequences of the seasonal migrations of birds

Pegan, T.; Kimmitt, A. A.; Benz, B. W.; Weeks, B. C.; Aubry, Y.; Burg, T.; Hudon, J.; Jones, A. W.; Kirchman, J. J.; Ruegg, K.; Winger, B.

10.1101/2024.06.28.601242 — evolutionary biology — Posted on 2024-07-02

4855 Evolution into chaos - implications of the trade-off between transmissibility and immune evasion

Sayyar, G.; Garab, A.; Rost, G.

10.1101/2024.06.29.601333 — evolutionary biology — Posted on 2024-07-02

4856 Density-dependent network structuring within and across wild animal systems

Albery, G. F.; Becker, D. J.; Firth, J. A.; Silk, M.; Sweeny, A. R.; Wal, E. V.; Webber, Q.; Allen, B.; Babayan, S. A.; Barve, S.; Begon, M.; Birtles, R. J.; Block, T. A.; Block, B. A.; Bradley, J. E.; Budischak, S.; Buesching, C.; Burthe, S. J.; Carlisle, A. B.; Caselle, J. E.; Cattuto, C.; Chaine, A. S.; Chapple, T.; Cheney, B. J.; Clutton-Brock, T.; Collier, M.; Curnick, D. J.; Delahay, R. J.; Farine, D. R.; Fenton, A.; Ferretti, F.; Fielding, H.; Foroughirad, V.; Frere, C.; Gardner, M. G.; Geffen, E.; Godfrey, S. S.; Graham, A. L.; Hammond, P. S.; Henrich, M.; Heurich, M.; Hopwood, P.; Ila

10.1101/2024.06.28.601262 — ecology — Posted on 2024-07-02

4857 Secondary metabolites shape Streptomyces-Streptomyces interaction: Mass Spectrometry Imaging reveals lydicamycins broadly induce sporulation

Jarmusch, S. A.; Schostag, M. D.; Yang, Z.; Wang, J.; Andersen, A. J. C.; Weber, T.; Ding, L.

10.1101/2024.06.28.600750 — ecology — Posted on 2024-07-02

4858 Different phylogenetic characteristics of Icterids: would they be evolutionary strategies to avoid parasitism by Molothrus spp.?

Barbosa, V. M.; Silva, B. D.; da Silva, V. X.; Hasui, E.

10.1101/2024.06.30.601453 — ecology — Posted on 2024-07-02

4859 Spatial structure affects the establishment and persistence of closed microbial ecosystems

Mansour, I.; Hähnlein, M.; Minkewitz, L.; Wilk, E. N.; Remus-Emsermann, M.; Antonovics, J.; Matthias, R. C.

10.1101/2024.06.28.601237 — ecology — Posted on 2024-07-02

4860 Phylogenetic and non-phylogenetic patterns in the richness, frequency and composition of links in a herbivore-parasitoid interaction network

Sinclair, F. H.; Tang, C.-T.; Bailey, R. A.; Csoka, G. L.; Melika, G.; Nicholls, J. A.; Nieves-Aldrey, J.-L.; Reiss, A.; Zhang, Y. M.; Phillimore, A.; Schonrogge, K.; Stone, G. N.

10.1101/2024.06.30.601383 — ecology — Posted on 2024-07-02

4861 Phospholipase Cgamma regulates lacrimal gland branching by competing with PI3K in phosphoinositide metabolism

Wang, Q.; Tao, C.; Wu, Y.; Anderson, K. E.; Hannan, A.; Lin, C.-s.; Hawkins, P. T.; Stephens, L.; Zhang, X.

10.1101/2024.06.28.601066 — developmental biology — Posted on 2024-07-02

4862 Non-autonomous insulin signaling regulates the duration of mitosis in C. elegans germline stem and progenitor cells

Gerhold, A. R.; Cheng, E.; Lu, R.

10.1101/2024.06.28.601188 — developmental biology — Posted on 2024-07-02

4863 The evolutionary modifications of a GoLoco motif in the AGS protein facilitate micromere formation in the sea urchin embryo

Emura, N.; Wavreil, F. D. M.; Fries, A.; Yajima, M.

10.1101/2024.06.30.601440 — developmental biology — Posted on 2024-07-02

4864 Anti-diabetic and anti-adipogenic effects of polyherbal formulation Varanadi kashayam with a focus on incretin modulation

Thottappillil, A.; Kouser, S.; Badiger, A. V.; Pinto, P. G.; Ramachandran, S.; Janadri, S.; Mudagal, M. P.; Kukkupuni, S. K.; Mohan S, S.; Chethala N, V.

10.1101/2024.06.29.601306 — cell biology — Posted on 2024-07-02

4865 PTEN Regulates Myofibroblast Activation in Valvular Interstitials Cells based on Subcellular Localization

Batan, D.; Tseropoulos, G.; Bishop, C.; Kirkpatrick, B. E.; Bera, K.; Khang, A.; Weiser-Evans, M. C.; Anseth, K. S.

10.1101/2024.06.30.601424 — cell biology — Posted on 2024-07-02

4866 Reorganization of the Flagellum Scaffolding Induces a Sperm Standstill During Fertilization

Jablonski, M.; Luque, G. M.; Gomez-Elias, M.; Sanchez-Cardenas, C.; Xu, X.; de la Vega-Beltran, J. L.; Corkidi, G.; Linares, A.; Abonza, V.; Arenas-Hernandez, A.; Ramos-Godinez, M. D. P.; Lopez-Saavedra, A.; Krapf, D.; Krapf, D.; Darszon, A.; Guerrero, A.; Buffone, M. G.

10.1101/2023.06.22.546073 — cell biology — Posted on 2024-07-02

4867 A positive list administered immunity system restricts the body size of insects

Ogata, N.; Matsuda, T.

10.1101/2024.06.30.600924 — immunology — Posted on 2024-07-02

4868 Distinct Mechanisms of T3SS Recognition Control LTB4 Synthesis in Neutrophils versus Macrophages

Brady, A.; Mora Martinez, L. C.; Hammond, B.; Bodduluri, H.; Uriarte, S. M.; Lawrenz, M. B.

10.1101/2024.07.01.601466 — immunology — Posted on 2024-07-02

4869 Tissue-specific immune transcriptional signatures in the bordering tissues of the mouse brain and retina

Etebar, F.; Whatmore, P.; Harkin, D. G.; Dando, S. J.

10.1101/2024.06.30.601438 — immunology — Posted on 2024-07-02

4870 Exploring Porphyromonas gingivalis Pathogenesis and Antibody Pool Effect Using a Novel Mouse Reproductive Model

Shi, X.; Xu, M. X.

10.1101/2024.06.28.601233 — immunology — Posted on 2024-07-02

4871 The RNA binding ubiquitination ligase MEX3B regulates bFGF-dependent neuronal proliferation.

Garg, K.; Sharma, G.; Samaddar, S.; Banerjee, S.

10.1101/2024.06.28.601280 — neuroscience — Posted on 2024-07-02

4872 Neural Stem Cell Relay from B1 to B2 cells in the adult mouse Ventricular-Subventricular Zone

Cebrian-Silla, A.; Assis Nascimento, M.; Mancia Leon, W.; Gonzalez-Granero, S.; Romero-Rodriguez, R.; Obernier, K.; Steffen, D. M.; Lim, D. A.; Garcia-Verdugo, J. M.; Alvarez-Buylla, A.

10.1101/2024.06.28.600695 — neuroscience — Posted on 2024-07-02

4873 Neuronal networks quantified as vector fields

Szeier, S.; Jorntell, H.

10.1101/2024.06.29.601314 — neuroscience — Posted on 2024-07-02

4874 Maternal dietary deficiencies in folic acid and choline change metabolites levels in offspring after ischemic stroke

Anwar, F.; Mosley, M.-T.; Jasbi, P.; Chi, J.; Gu, H.; Jadavji, N. M.

10.1101/2024.06.29.601358 — neuroscience — Posted on 2024-07-02

4875 The aging musician: Evidence of a downward trend in song tempo as a function of artist age

Luck, G.; Ansani, A.

10.1101/2024.06.29.601154 — neuroscience — Posted on 2024-07-02

4876 Scene context and attention independently facilitate MEG decoding of object category

Leticevscaia, O.; Brandman, T.; Peelen, M. V.

10.1101/2024.06.30.601374 — neuroscience — Posted on 2024-07-02

4877 Sensorimotor awareness requires intention: Evidence from minuscule eye movements.

Klanke, J.-N.; Ohl, S.; Rolfs, M.

10.1101/2024.07.02.601661 — neuroscience — Posted on 2024-07-02

4878 Ultradian rhythms of CRHPVN neuron activity, behaviour and stress hormone secretion

Zheng, S.; Focke, C. M. B.; Young, C. K.; Tripp, I.; Ganeshan, D.; Power, E.; Schwenke, D. O.; Herbison, A.; Kim, J. S.; Iremonger, K. J.

10.1101/2024.06.30.601439 — neuroscience — Posted on 2024-07-02

4879 Functional ultrasound neuroimaging reveals mesoscopic organization of saccades in the lateral intraparietal area of posterior parietal cortex

Griggs, W. S.; Norman, S. L.; Tanter, M.; Liu, C.; Christopoulos, V.; Shapiro, M. G.; Andersen, R. A.

10.1101/2024.06.28.600796 — neuroscience — Posted on 2024-07-02

4880 Morphological simulation tests the limits on phenotype discovery in 3D image analysis

Roston, R. A.; Whikehart, S. M.; Rolfe, S. M.; Maga, A. M.

10.1101/2024.06.30.601430 — zoology — Posted on 2024-07-02

4881 Iron deprivation activates aboveground cell wall biosynthesis in Populus and the role of PtrbHLH011

Tadesse, D.; Dai, Y.; Yang, L.; Yang, Y.; Dwivedi, N.; Kumaran, D.; Blaby-Haas, C.; Lipzen, A. M.; Santiago, K.; Barry, K. W.; Liu, C.-J.; Xie, M.

10.1101/2024.06.28.601228 — plant biology — Posted on 2024-07-02

4882 Berberine Bridge enzyme-like oxidases orchestrate homeostatic control and signaling of oligogalacturonides in defense and wounding

Salvati, A.; Diomaiuti, A.; Locci, F.; Gravino, M.; Gramegna, G.; Ilyas, M.; Benedetti, M.; Costantini, S.; De Caroli, M.; Castel, B.; Jones, J. D.; Cervone, F.; Pontiggia, D.; De Lorenzo, G.

10.1101/2024.06.28.601198 — plant biology — Posted on 2024-07-02

4883 Reduced leaf numbers due to shade avoidance allows sugar beet to maintain biomass under drought stress

Ballenger, J. G.; Adjesiwor, A. T.; Ewers, B. E.; Weinig, C.; Kniss, A. R.

10.1101/2024.06.28.601301 — plant biology — Posted on 2024-07-02

4884 Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients

Nikeghbal, P.; Burke, D.; Steinkamp, M. P.

10.1101/2024.06.28.601283 — cancer biology — Posted on 2024-07-02

4885 Label-Free Melanoma Phenotype Classification Using Artificial Intelligence-Based Morphological Profiling

Lattmann, E.; Jovic, A.; Kim, J.; Pham, T.; Corona, C.; Lian, Z.; Saini, K.; Ray, M.; Lu, V.; Tastanova, A.; Boutet, S. C.; Levesque, M. P.

10.1101/2024.06.28.601235 — cancer biology — Posted on 2024-07-02

4886 Clustering of RNA Polymerase II C-Terminal Domain Models upon Phosphorylation

Amith, W. D.; Chen, V. T.; Dutagaci, B.

10.1101/2024.06.28.601284 — biophysics — Posted on 2024-07-02

4887 Navigating the Maze of Mass Spectra: A Machine-Learning Guide to Identifying Diagnostic Ions in O-Glycan Analysis

Urban, J.; Joeres, R.; Thomes, L.; Thomsson, K. A.; Bojar, D.

10.1101/2024.06.28.601175 — bioinformatics — Posted on 2024-07-02

4888 Maloja: simple and scalable Snakemake workflow orchestration in the cloud

Giustizia, J.; Hodgson, W.; Andress, C.; Bilkhu, S.; Macklin, J.; Kess, T.

10.1101/2024.06.28.601236 — bioinformatics — Posted on 2024-07-02

4889 Active surveillance for influenza A virus in swine reveals within-farm reassortment and cocirculation of distinct subtypes and genetic clades

Thomas, M. N.; Janzen, G. M.; Markin, A. K.; Sharma, A.; Hewitt, K. S.; Li, G.; Baker, A. L.; Gauger, P. C.; Anderson, T. K.

10.1101/2024.06.28.601245 — bioinformatics — Posted on 2024-07-02

4890 ADM: Adaptive Graph Diffusion for Meta-Dimension Reduction

Feng, J.; Yong, L.; Yu, T.

10.1101/2024.06.28.601128 — bioinformatics — Posted on 2024-07-02

4891 Aberrant N-glycosylation is a therapeutic target in carriers of a common and highly pleiotropic mutation in the manganese transporter ZIP8

Tomar, V.; Kang, J.; Lin, R.; Brant, S. R.; Lazarev, M.; Tressler, C.; Glunde, K.; Zachara, N.; Melia, J. M.

10.1101/2024.06.28.601207 — genomics — Posted on 2024-07-02

4892 Atf4 protects islet beta-cell identity and function under acute glucose-induced stress but promotes beta-cell failure in the presence of free fatty acid

Yagan, M.; Najam, S.; Hu, R.; Wang, Y.; DAdi, P.; Xu, Y.; Simmons, A. J.; Stein, R.; Adams, C. M.; Jacobson, D. J.; Lau, K.; Liu, Q.; Gu, G.

10.1101/2024.06.28.601249 — genetics — Posted on 2024-07-02

4893 The coevolution of learning schedules and teaching enhances cumulative knowledge and drives a teacher-innovator syndrome

Maisonneuve, L.; Lehmann, L.; Mullon, C.

10.1101/2024.06.28.601211 — evolutionary biology — Posted on 2024-07-02

4894 Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells Within Distinct Zones

Dong, R.; Li, H.; He, X. C.; Wang, C.; Perera, A.; Malloy, S.; Russell, J.; Li, W.; Petentler, K.; Mao, X.; Yang, Z.; Epp, M.; Hall, K.; Scott, A.; Smith, S.; Hembree, M.; Wang, Y.; McKinney, S.; Haug, J.; Unruh, J.; Slaughter, B.; Kang, X.; Li, L.

10.1101/2024.06.28.601225 — developmental biology — Posted on 2024-07-02

4895 TSC2 loss in neural progenitor cells suppresses translation of ASD/NDD-associated transcripts in an mTORC1- and MNK1/2-reversible fashion

Martin, P.; Szkop, K.; Robert, F.; Bhattacharyya, S.; Beauchamp, R.; Brenner, J.; Redmond, N.; Huang, S.; Erdin, S.; Larsson, O.; Ramesh, V.

10.1101/2024.06.04.597393 — molecular biology — Posted on 2024-07-02

4896 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats

Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.

10.1101/2023.11.03.565335 — immunology — Posted on 2024-07-02

4897 Activity-dependent lateral inhibition enables ensemble synchronization of odor-activated neurons in the olfactory bulb

Dalal, T.; Haddad, R.

10.1101/2024.06.24.600470 — neuroscience — Posted on 2024-07-02

4898 Glutathione Oxidation in Cerebrospinal Fluid as a Biomarker of Oxidative Stress in Amyotrophic Lateral Sclerosis

Pham, T. K.; Verber, N.; Turner, M. R.; Malaspina, A.; Collins, M. O.; Mead, R. J.; Shaw, P. J.

10.1101/2024.07.01.601162 — neuroscience — Posted on 2024-07-02

4899 Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera)

Powell, A.; Heckenhauer, J.; Pauls, S. U.; Rios-Touma, B.; Kuranishi, R. B.; Holzenthal, R. W.; Razuri-Gonzales, E.; Bybee, S.; Frandsen, P. B.

10.1101/2023.12.15.571940 — genomics — Posted on 2024-07-02

4900 The sensory shark: high-quality morphological, genomic and transcriptomic data for the small spotted catshark Scyliorhinus canicula reveal the molecular bases of sensory organ evolution in jawed vertebrates

Mayeur, H.; Leyhr, J.; Mulley, J.; Nicolas, L.; Michel, L.; Sharma, K.; Lagadec, R.; Aury, J.-M.; Osborne, O. G.; Mulhair, P.; Poulain, J.; Mangenot, S.; Mead, D.; Smith, M.; Corton, C.; Oliver, K.; Skelton, J.; Betteridge, E.; Dolucan, J.; Dudchenko, O.; Omer, A.; Weisz, D.; Lieberman-Aiden, E.; McCarthy, S.; Sims, Y.; Torrance, J.; Tracey, A.; Howe, K.; Baril, T.; Hayward, A.; Martinand-Mari, C.; Sanchez, S.; Haitina, T.; Martin, K. J.; MAZAN, S.; Korsching, S. I.; Debiais-Thibaud, M.

10.1101/2024.05.23.595469 — evolutionary biology — Posted on 2024-07-02

4901 Experimental design impacts the vector competence of Ornithodoros ticks for African swine fever virus: a meta-analysis of published evaluations

Bernard, J.; Madeira, S.; Otte, J.; Boinas, F.; Le Potier, M.-F.; Vial, L.; Jourdan-Pineau, H.

10.1101/2023.11.10.566648 — ecology — Posted on 2024-07-02

4902 Endothelial Zmiz1 modulates physiological and pathophysiological angiogenesis during retinal development

Patel, N. R.; K C, R.; Chiang, M.; Meadows, S.

10.1101/2024.06.30.601426 — developmental biology — Posted on 2024-07-02

4903 Porphyromonas gingivalis activates Heat-Shock-Protein 27 to drive a LC3C-specific pro-bacterial form of select autophagy that is redox sensitive for intracellular survival in human gingival mucosa

Wellslager, B.; Roberts, J.; Chowdhury, N.; Madan, L.; Orellana, E.; Yilmaz, O.

10.1101/2024.07.01.601539 — microbiology — Posted on 2024-07-02

4904 An Artificial Intelligence Model for Profiling the Landscape of Antigen-binding Affinities of Massive BCR Sequencing Data

10.1101/2024.06.27.601035 — immunology — Posted on 2024-07-02

4905 SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

Mistri, S. K.; Hilton, B. M.; Horrigan, K. J.; Andretta, E. S.; Savard, R.; Dienz, O.; Hampel, K. J.; Gerrard, D. L.; Rose, J. T.; Sidiropoulos, N.; Majumdar, D.; Boyson, J. E.

10.1101/2024.01.10.575073 — immunology — Posted on 2024-07-02

4906 T cells Instruct Immune Checkpoint Inhibitor Therapy Resistance in Tumors Responsive to IL-1 and TNFa Inflammation.

Cho, N. W.; Guldberg, S. M.; Nabet, B. Y.; Yu, J. Z.; Kim, E. J.; Hiam-Galvez, K. J.; Yee, J. L.; DeBarge, R.; Tenvooren, I.; Ashitey, N. A.; Lynce, F.; Dillon, D. A.; Rosenbluth, J. M.; Spitzer, M. H.

10.1101/2022.09.20.508732 — immunology — Posted on 2024-07-02

4907 Dopamine D1 receptor expression in dlPFC inhibitory parvalbumin neurons may contribute to higher visuospatial distractibility in marmosets versus macaques

Joyce, M. K. P.; Ivanov, T. G.; Krienen, F.; Mitchell, J.; Ma, S.; Inoue, W.; Nandy, A. P.; Datta, D.; Duque, A.; Arellano, J. I.; Gupta, R.; Gonzalez-Burgos, G.; Lewis, D. A.; Sestan, N.; McCarroll, S. A.; Martinez-Trujillo, J. C.; Froudist-Walsh, S.; Arnsten, A. F.

10.1101/2024.06.15.599163 — neuroscience — Posted on 2024-07-02

4908 Oral Fentanyl Consumption and Withdrawal Impairs Fear Extinction Learning and Enhances Basolateral Amygdala Principal Neuron Excitatory-Inhibitory Balance in Male and Female Mice

Downs, A. M.; Kmiec, G.; McElligott, Z. A.

10.1101/2023.11.28.569085 — neuroscience — Posted on 2024-07-02

4909 Fast 3D imaging in the auditory cortex of awake mice reveals that astrocytes control neurovascular coupling responses locally at arteriole-capillary junctions.

Lind, B. L.; Volterra, A.

10.1101/2024.06.28.601145 — neuroscience — Posted on 2024-07-02

4910 Slow and steady: auditory features that drive learnability in animal vocalizations

DiTullio, R. W.; Wei, L.; Balasubramanian, V.

10.1101/2024.06.20.599962 — neuroscience — Posted on 2024-07-02

4911 Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APPNL-F/NL-F Mice.

Fang, Y.; Peck, M. R.; Quinn, K.; Chapman, J. E.; Medina, D.; McFadden, S. A.; Bartke, A.; Hascup, K. N.; Hascup, E. R.

10.1101/2023.12.12.571277 — neuroscience — Posted on 2024-07-02

4912 Transpirational water loss from flowers is low but unregulated

Roddy, A.; Schreel, J.; Paiva, D.; Qin, N.; Jiang, G.-F.; Brodersen, C. R.; Simonin, K.

10.1101/2024.06.28.600864 — plant biology — Posted on 2024-07-02

4913 Sympathetic neuron-derived NPY protects from obesity by sustaining the mural progenitors of thermogenic adipocytes.

Zhu, Y.; Yao, L.; Gallo-Ferraz, A. L.; Bombassaro, B.; Simoes, M. R.; Abe, I.; Chen, J.; Sarker, G.; Ciccarelli, A.; Lee, C.; Martinez-Sanchez, N.; Dustin, M.; Anderson, K.; Zhan, C.; Horvath, T.; Velloso, L.; Kajimura, S.; Domingos, A. I.

10.1101/2024.05.18.594804 — physiology — Posted on 2024-07-02

4914 In vitro genotoxic and mutagenic potentials of combustion particles from marine fuels with different sulfur contents

Jeong, S.; Pantzke, J.; Offer, S.; Kaefer, U.; Bendl, J.; Saraji-Bozorgzad, M.; Huber, A.; Michalke, B.; Etzien, U.; Jacobi, G.; Orasche, J.; Czech, H.; Rueger, C. P.; Schnelle-Kreis, J.; Streibel, T.; Buchholz, B.; Adam, T.; Sklorz, M.; Di Bucchianico, S.; Zimmermann, R.

10.1101/2024.06.27.601016 — pharmacology and toxicology — Posted on 2024-07-02

4915 Collagen modification remodels the sarcoma tumor microenvironment and promotes resistance to immune checkpoint inhibition

Pan, H.; Liu, Y.; Fuller, A. M.; Williams, E. F.; Fraietta, J. A.; Eisinger-Mathason, T. S. K.

10.1101/2024.06.28.601055 — cancer biology — Posted on 2024-07-02

4916 circPCMTD1: A protein-coding circular RNA that regulates DNA damage response in BCR/ABL-positive leukemias

Papaioannou, D.; Urs, A. P.; Buisson, R.; Petri, A.; Kulkarni, R.; Nicolet, D.; Woodward, L.; Goda, C.; Mrozek, K.; Behbehani, G. K.; Kauppinen, S.; Eisfeld, A.-K.; Aifantis, I.; Singh, G.; Dorrance, A. M.; Garzon, R.

10.1101/2024.06.27.601046 — cancer biology — Posted on 2024-07-02

4917 Lineage-dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and independent immunotherapeutic targets

Kendsersky, N. M.; Odrobina, M.; Mabe, N. W.; Farrel, A.; Grossmann, L.; Tsang, M.; Wolpaw, A. J.; Zammarchi, F.; van Berkel, P. H.; Dang, C. V.; Mosse, Y. P.; Stegmaier, K.; Maris, J.

10.1101/2024.06.27.600865 — cancer biology — Posted on 2024-07-02

4918 The m6A reader IGF2BP3 promotes gastric cancer progression via increasing the expression of FBXO32 protein

Si, Y.; Tian, B.; Zhang, R.; Xuan, M.; Liu, K.; Jiao, J.; Han, S.; Li, H.; Hu, Y.; Zhao, H.; He, W.; Wang, J.; Liu, T.; Yu, W.

10.1101/2024.06.28.601102 — cancer biology — Posted on 2024-07-02

4919 EstroGene2.0: A multi-omic database of response to estrogens, ER-modulators, and resistance to endocrine therapies in breast cancer

Li, Z.; Chen, F.; Chen, L.; Liu, J.; Tseng, D.; Hadi, F.; Omarjee, S.; Kishore, K.; Kent, J.; Kirkpatrick, J.; DSantos, C.; Lawson, M.; Gertz, J.; Sikora, M. J.; McDonnell, D. J.; Carroll, J.; Polyak, K.; Oesterreich, S.; LEE, A. V.

10.1101/2024.06.28.601163 — cancer biology — Posted on 2024-07-02

4920 Dynamic regions allosterically connect the USP14 active site with the proteasome interaction surface

Salomonsson, J.; Sjostrand, L.; Eskilson, A.; Derbyshire, D.; D'Arcy, P.; Sunnerhagen, M.; Ahlner, A.

10.1101/2024.06.28.601165 — biophysics — Posted on 2024-07-02

4921 Investigating Ligand-Mediated Conformational Dynamics of Pre-miR21: A Machine-Learning-Aided Enhanced Sampling Study

Aureli, S.; Bellina, F.; Rizzi, V.; Gervasio, F. L.

10.1101/2024.06.27.601024 — biophysics — Posted on 2024-07-02

4922 SCEMENT: Scalable and Memory Efficient Integration of Large-scale Single Cell RNA-sequencing Data

Chockalingam, S. P.; Aluru, M.; Aluru, S.

10.1101/2024.06.27.601027 — bioinformatics — Posted on 2024-07-02

4923 Ultrafast and accurate sequence alignment and clustering of viral genomes

Zielezinski, A.; Gudys, A.; Barylski, J.; Siminski, K.; Rozwalak, P.; Dutilh, B. E.; Deorowicz, S.

10.1101/2024.06.27.601020 — bioinformatics — Posted on 2024-07-02

4924 Critical roles of Ikaros and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia

Ding, Y.; He, B.; Bogush, D.; Schramm, J.; Singh, C.; Dovat, K.; Randazzo, J.; Tukaramrao, D.; Hengst, J.; Annageldiyev, C.; Kudva, A.; Desai, D.; Sharma, A.; Spiegelman, V. S.; Huang, S.; Viet, C. T.; Dorsam, G.; Saulnier Scholler, G.; Broach, J.; Yue, F.; Dovat, S.

10.1101/2024.06.27.600861 — bioinformatics — Posted on 2024-07-02

4925 spatialGE: A user-friendly web application to democratize spatial transcriptomics analysis

Ospina, O. E.; Manjarres-Betancur, R.; Gonzalez-Calderon, G.; Soupir, A. C.; Smalley, I.; Tsai, K. Y.; Markowitz, J.; Vallebuona, E.; Berglund, A.; Eschrich, S. A.; Yu, X.; Fridley, B. L.

10.1101/2024.06.27.601050 — bioinformatics — Posted on 2024-07-02

4926 GenomeDelta: detecting recent transposable element invasions without repeat library

Pianezza, R.; Haider, A.; Kofler, R.

10.1101/2024.06.28.601149 — bioinformatics — Posted on 2024-07-02

4927 Read Length Dominates Phylogenetic Placement Accuracy of Ancient DNA Reads

Bettisworth, B.; Psonis, N.; Poulakakis, N.; Pavlidis, P.; Stamatakis, A.

10.1101/2024.06.28.601240 — bioinformatics — Posted on 2024-07-02

4928 DLKcat cannot predict meaningful kcat values for mutants and unfamiliar enzymes

Kroll, A.; Lercher, M. J.

10.1101/2023.02.06.526991 — bioinformatics — Posted on 2024-07-02

4929 Joint and tissue mechanics in post-traumatic osteoarthritis: insights from the rat model

Piet, J.; Elahi, S. A.; Esrafilian, A.; Mielke, F.; Van Nuffel, M.; Orozco, G. A.; Vancleef, S.; Lories, R.; Korhonen, R. K.; Aerts, P.; Van Wassenbergh, S.; Jonkers, I.

10.1101/2024.06.27.601039 — bioengineering — Posted on 2024-07-02

4930 IGF-1 Peptide Mimetic-functionalized Hydrogels Enhance MSC Survival and Immunomodulatory Activity

Tan, X.; Jing, L.; Neal, S. M.; Gupta, M. C.; Buchowski, J. M.; Setton, L. A.; Huebsch, N.

10.1101/2024.06.27.600680 — bioengineering — Posted on 2024-07-02

4931 PV+ optogenetic stimulations at specific frequencies in specific brain regions can restore navigational flexibility in an acute MK801 mouse model of schizophrenia

Patrono, E.; Cernotova, D.; Svoboda, J.; Stuchlik, A.

10.1101/2024.06.28.601158 — animal behavior and cognition — Posted on 2024-07-02

4932 Unravelling complex hybrid and polyploid evolutionary relationships using phylogenetic placement of paralogs from target enrichment data

Walden, N.; Kiefer, C.; Koch, M. A.

10.1101/2024.06.28.601132 — evolutionary biology — Posted on 2024-07-02

4933 Divergent lineages in a young species: the case of Datilillo (Yucca valida), a broadly distributed plant from the Baja California Peninsula

Aleman, A.; Arteaga, M. C.; Gasca-Pineda, J.; Bello-Bedoy, R.

10.1101/2023.05.22.541794 — evolutionary biology — Posted on 2024-07-02

4934 Linking selection to demography in experimental evolution of active death in a unicellular organism

Zeballos, N.; Rieu, O.; Fereol, S.; Leung, C.; Chevin, L.-M.

10.1101/2024.06.28.601143 — evolutionary biology — Posted on 2024-07-02

4935 Repeated global adaptation across plant species

Nocchi, G.; Whiting, J. R.; Yeaman, S.

10.1101/2024.04.02.587814 — evolutionary biology — Posted on 2024-07-02

4936 Glial voltage-gated K+ channels modulate the neural abiotic stress tolerance of Drosophila melanogaster

Andersen, M. K.; Livingston, D. B. H.; Robertson, R. M.; MacMillan, H. A.

10.1101/2024.06.28.601156 — neuroscience — Posted on 2024-07-02

4937 Peripheral glia and neurons jointly regulate activity-induced synaptic remodeling at the Drosophila neuromuscular junction

Chang, Y.-C.; Peng, Y.-J.; Lee, J. Y.; Chang, K. T.

10.1101/2024.06.27.600908 — neuroscience — Posted on 2024-07-02

4938 Uncertainty gates redundancy in reward integration in prefrontal-cortical and ventral-hippocampal nucleus accumbens inputs to tune engagement

Iyer, E. S.; Vitaro, P.; Wu, S.; Muir, J.; Tse, Y. C.; Cvetkovska, V.; Bagot, R. C.

10.1101/2024.06.27.601063 — neuroscience — Posted on 2024-07-02

4939 An applicable and efficient retrograde monosynaptic circuit mapping tool for larval zebrafish

Chen, T.; Deng, Q.; Lin, K.; Zheng, X.; Wang, X.; Zhong, Y.; Ning, X.; Li, Y.; Xu, F.; Du, J.; Du, X.

10.1101/2024.06.27.601104 — neuroscience — Posted on 2024-07-02

4940 A comparative analysis across species of maternal mRNA regulation in embryos using QUANTA

Tawil, M.; Alcalay, D.; Greenberg, P.; Har-Sheffer, S.; Fishman, L.; Rabani, M.

10.1101/2024.06.27.600954 — systems biology — Posted on 2024-07-02

4941 Differential expression ofCCD4(4B) drives natural variation in fruit carotenoidcontent in strawberry ( Fragaria spp.)

Amaya, I.; Roldan-Guerra, F. J.; Ordonez, J. L.; Torreblanca, R.; Wagner, H.; Waurich, V.; Olbricht, K.; Moreno-Rojas, J. M.; Sanchez Sevilla, J. F.; CASTILLEJO, C.

10.1101/2024.07.02.601541 — plant biology — Posted on 2024-07-02

4942 Deep mutational scanning reveals sequence to function constraints for SWEET family transporters

Narayanan, K.; Weigle, A. T.; Xu, L.; Mi, X.; Zhang, C.; Chen, L.-Q.; Procko, E.; Shukla, D.

10.1101/2024.06.28.601307 — plant biology — Posted on 2024-07-02

4943 The Arabidopsis thaliana core splicing factor PORCUPINE/SmE1 requires intron-mediated expression

Dikaya, V.; Rojas-Murcia, N.; Benstein, R. M.; Eiserhardt, W. L.; Schmid, M.

10.1101/2024.07.02.601721 — plant biology — Posted on 2024-07-02

4944 Differential Toxicity of Perfluorooctane Sulfonate (PFOS) in Wild-Type and Oatp1d1 Mutant Zebrafish Embryos

Mihaljevic, I.; Vujica, L.; Dragojavic, J.; Loncar, J.; Smital, T.

10.1101/2024.06.28.601146 — pharmacology and toxicology — Posted on 2024-07-02

4945 Sponges of the Lower Greensand Group (Lower Cretaceous) of England; a revision

Sendino, C.; Kershaw, S.

10.1101/2024.06.28.601142 — paleontology — Posted on 2024-07-02

4946 Mechanical evolution of metastatic cancer cells in three-dimensional microenvironment

Hilai, K.; Grubich, D.; Akrawi, M.; Zhu, H.; Zaghloul, R.; Shi, C.; Do, M.; Zhu, D.; Zhang, J.

10.1101/2024.06.27.601015 — biophysics — Posted on 2024-07-02

4947 Uncovering differential tolerance to deletions versus substitutions with a protein language model

Goldman, G.; Chati, P.; Ntranos, V.

10.1101/2024.06.27.601077 — bioinformatics — Posted on 2024-07-02

4948 Joint exome and metabolome analysis in individuals with dyslexia: Evidence for associated dysregulations of olfactory perception and autoimmune functions

Nandakumar, R.; Shi, X.; Gu, H.; Kim, Y.; Raskind, W.; Peter, B.; Dinu, V.

10.1101/2024.06.27.600448 — bioinformatics — Posted on 2024-07-02

4949 GeneBag: training a cell foundation model for broad-spectrum cancer diagnosis and prognosis with bulk RNA-seq data

Liang, Y.; Li, D.; Xu, A. G.; Shao, Y.; Tang, K.

10.1101/2024.06.27.601098 — bioinformatics — Posted on 2024-07-02

4950 APV9WR: An Integrated Web Resource of Alpha papillomavirus 9 for Genomics, Proteomics, Phylogenetic and Therapeutic Analysis

Kulshreshtha, A.; Goel, V.; Verma, A.; Goel, S.; Sharma, S.; Bhowmik, R.; Aspatwar, A.

10.1101/2024.06.28.601125 — bioinformatics — Posted on 2024-07-02

4951 Despotic long-tailed macaques benefit others in a group service paradigm

de Laat, E.; Waasdorp, S.; Roth, T.; Massen, J.; Sterck, E.

10.1101/2024.06.28.601131 — animal behavior and cognition — Posted on 2024-07-02

4952 Wound closure after brain injury relies on force generation by microglia in zebrafish

El-Daher, F.; Drake, L. K.; Enos, S. J.; Wehner, D.; Westphal, M.; Porter, N. J.; Becker, C. G.; Becker, T.

10.1101/2024.06.04.597300 — neuroscience — Posted on 2024-07-02

4953 Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells

Huang, Y.; Mo, H.; Yang, J.; Gao, L.; Tao, T.; Shu, Q.; Guo, W.; Zhao, Y.; Lyu, J.; Wang, Q.; Guo, J.; Zhai, H.; Zhu, L.; Chen, H.; Xu, G.

10.1101/2024.04.01.587569 — physiology — Posted on 2024-07-02

4954 Approaching Maximum Resolution in Structured Illumination Microscopy via Accurate Noise Modeling

Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.

10.1101/2023.12.07.570701 — biophysics — Posted on 2024-07-02

4955 Castanet: a pipeline for rapid analysis of targeted multi-pathogen genomic data

10.1101/2024.06.28.601013 — bioinformatics — Posted on 2024-07-02

4956 plasma: Partial LeAst Squares for Multiomics Analysis

Yamaguchi, K.; Abdelbaky, S.; Yu, L.; Oakes, C. C.; Abruzzo, L. V.; Coombes, K. R.

10.1101/2023.03.10.532096 — bioinformatics — Posted on 2024-07-02

4957 Hydrogels for Local and Sustained Delivery of Bacteriophages to Treat Wound Infections

Lin, Y.-H.; Dharmaraj, T.; Chen, Q.; Echterhof, A.; Manasherob, R.; Zheng, L. J.; de Leeuw, C.; Peterson, N. A.; Stannard, W.; Li, Z.; Hajfathalian, M.; Hargil, A.; Martinez, H. A.; Chang, T. H. W.; Blankenberg, F. G.; Amanatullah, D.; Chaudhuri, O.; Bollyky, P. L.

10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-07-02

4958 Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1

Kozlov, G.; Jiang, J.; Rutherford, T.; Noronha, A.; Wilds, C.; Gehring, K.

10.1101/2024.05.08.593157 — biochemistry — Posted on 2024-07-02

4959 A Unified Approach to Investigating 4 dpf Zebrafish Larval Behaviour through a Standardised Light/Dark Assay

Hillman, C. S.; Kearn, J.; Parker, M. O.

10.1101/2023.11.23.568441 — animal behavior and cognition — Posted on 2024-07-02

4960 Reversion to metabolic autonomy underpins evolutionary rescue of a bacterial obligate mutualism

Melero-Jimenez, I. J.; Sorokin, Y.; Merlin, A.; Couce, A.; Friedman, J.

10.1101/2024.06.27.600993 — evolutionary biology — Posted on 2024-07-02

4961 Positive feedback between demographic and selective fluctuations can greatly amplify the random fluctuation of population size

Kim, Y.

10.1101/2024.06.13.598821 — evolutionary biology — Posted on 2024-07-02

4962 A direct experimental test of Ohno's hypothesis

Mihajlovic, L.; Iyengar, B. R.; Baier, F.; Barbier, I.; Iwaszkiewicz, J.; Zoete, V.; Wagner, A.; Schaerli, Y.

10.1101/2023.09.25.559237 — evolutionary biology — Posted on 2024-07-02

4963 Weighting of sensory cues reflect changing patterns of visual investment during ecological divergence in Heliconius butterflies.

Borrero, J.; Mogollon Perez, E. A.; Wright, D. S.; Lozano, D.; Rueda-Munoz, G.; Pardo-Diaz, C.; Salazar, C.; Montgomery, S. H.; Merrill, R. M.

10.1101/2024.04.03.587949 — evolutionary biology — Posted on 2024-07-02

4964 Scalable Hypothalamic Arcuate Neuron Differentiation from Human Pluripotent Stem Cells Suitable for Modeling Metabolic and Reproductive Disorders

Jovanovic, V. M.; Narisu, N.; Bonnycastle, L. L.; Tharakan, R.; Mesch, K. T.; Glover, H. J.; Yan, T.; Sinha, N.; Sen, C.; Castellano, D.; Yang, S.; Blivis, D.; Ryu, S.; Bennett, D. F.; Rosales-Soto, G.; Inman, J.; Ormanoglu, P.; LeClair, C. A.; Xia, M.; Schneider, M.; Hernandez-Ochoa, E. O.; Erdos, M. R.; Simeonov, A.; Chen, S.; Singec, I.; Collins, F. S.; Doege, C. S.; Tristan, C. A.

10.1101/2024.06.27.601062 — developmental biology — Posted on 2024-07-02

4965 A novel family of lncRNAs relate facioscapulohumeral muscular dystrophy to nucleolar architecture and protein synthesis

Salsi, V.; Losi, F.; Fosso, B.; Ferrarini, M.; Pini, S.; Manfredi, M.; Vattemi, G. N. A.; Mongini, T. E.; Maggi, L.; Pesole, G. D.; Henras, A.; Kaufman, P. D.; McStay, B.; Tupler, R. G.

10.1101/2024.06.29.600824 — molecular biology — Posted on 2024-07-02

4966 Analysis of RNA translation with a deep learning architecture provides new insight into translation control

Fan, X.; Chang, T.; Chen, C.; Hafner, M.; Wang, Z.

10.1101/2023.07.08.548206 — molecular biology — Posted on 2024-07-02

4967 Molecular basis of neurodegeneration in a mouse model of Polr3-related disease

Moir, R. D.; Merheb, E.; Chitu, V.; Stanley, E. R.; Willis, I. M.

10.1101/2023.12.12.571310 — molecular biology — Posted on 2024-07-02

4968 The Evolution of Heteroresistance via Small Colony Variants in Escherichia coli Following Long Term Exposure to Bacteriostatic Antibiotics

Gil-Gil, T.; Berryhill, B. A.; Manuel, J. A.; Smith, A. P.; Baquero, F.; Levin, B. R.

10.1101/2023.10.30.564761 — microbiology — Posted on 2024-07-02

4969 Persistent cross-species transmission systems dominate Shiga toxin-producing Escherichia coli O157:H7 epidemiology in a high incidence region: a genomic epidemiology study

Tarr, G. A. M.; Chui, L.; Stanford, K.; Bumunang, E. W.; Zaheer, R.; Li, V.; Freedman, S.; Laing, C. R.; McAllister, T. A.

10.1101/2024.04.05.588308 — microbiology — Posted on 2024-07-02

4970 Shortcutting from self-motion signals: quantifying trajectories and active sensing in an open maze

Xu, J.; Girardi-Schappo, M.; Beique, J.-C.; Longtin, A.; Maler, L.

10.1101/2023.02.24.529984 — neuroscience — Posted on 2024-07-02

4971 The frontal cortex adjusts striatal integrator dynamics for flexible motor timing

Yang, Z.; Inagaki, M.; Gerfen, C.; Fontolan, L.; Inagaki, H. K.

10.1101/2024.06.29.601348 — neuroscience — Posted on 2024-07-02

4972 Ageing impacts basic auditory and timing processing

Criscuolo, A.; Schwartze, M.; Bonetti, L.; Kotz, S. A.

10.1101/2024.03.24.586049 — neuroscience — Posted on 2024-07-02

4973 Dopamine Dynamics Underlying Alloparental Behavioral Acquisition Facilitated by Top-down Orbitofrontal Inputs in Female Mice

Tasaka, G.-i.; Hagihara, M.; Irie, S.; Kobayashi, H.; Inada, K.; Kobayashi, K.; Kato, S.; Kobayashi, K.; Miyamichi, K.

10.1101/2023.02.03.527077 — neuroscience — Posted on 2024-07-02

4974 Control of innate olfactory valence by segregated cortical amygdala circuits

Howe, J. R.; Chan, C.-L.; Lee, D.; Blanquart, M.; Romero, H.; Zadina, A. N.; Lemieux, M. E.; Desplats, P. A.; Tye, K. M.; Root, C. M.

10.1101/2024.06.26.600895 — neuroscience — Posted on 2024-07-02

4975 Joint inference of discrete cell types and continuous type-specific variability in single-cell datasets with MMIDAS

Marghi, Y.; Gala, R.; Baftizadeh, F.; Sumbul, U.

10.1101/2023.10.02.560574 — neuroscience — Posted on 2024-07-02

4976 Spike-phase coupling of subthalamic neurons to posterior opercular cortex predicts speech sound accuracy

Vissani, M.; Bush, A.; Lipski, W. J.; Bullock, L.; Fischer, P.; Neudorfer, C.; Holt, L. L.; Fiez, J. A.; Turner, R. S.; Richardson, R. M.

10.1101/2023.10.18.562969 — neuroscience — Posted on 2024-07-02

4977 Cellular and Molecular Changes During Aging in MEC: Unveiling the Role of Bglap3 Neurons in Cognitive Aging

Miao, C.; Cao, Q.; Uzeen, S.; Cheng, S.; Liu, Y.; Liu, J.; Wen, S.; Zhong, M.; Hao, J.; Yao, S.; Yang, Y.; Yan, X.; Guo, W.

10.1101/2024.06.27.600930 — neuroscience — Posted on 2024-07-02

4978 Emotional Content and Semantic Structure of Dialogues Predict Interpersonal Neural Synchrony in the Prefrontal Cortex: a Hyperscanning Studywith Functional Near-Infrared Spectroscopy

Carollo, A.; Stella, M.; Lim, M.; Bizzego, A.; Esposito, G.

10.1101/2024.02.15.580458 — neuroscience — Posted on 2024-07-02

4979 Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language

Hong, Z.; Wang, K.; Zada, Z.; Gazula, H.; Turner, D.; Aubrey, B.; Niekerken, L.; Doyle, W.; Devore, S.; Dugan, P.; Friedman, D.; Devinsky, O.; Flinker, A.; Hasson, U.; Nastase, S.; Goldstein, A.

10.1101/2024.06.12.598513 — neuroscience — Posted on 2024-07-02

4980 Simulating 500 million years of evolution with a language model

Hayes, T.; Rao, R.; Akin, H.; Sofroniew, N. J.; Oktay, D.; Lin, Z.; Verkuil, R.; Tran, V. Q.; Deaton, J.; Wiggert, M.; Badkundri, R.; Shafkat, I.; Gong, J.; Derry, A.; Molina, R. S.; Thomas, N.; Khan, Y. A.; Mishra, C.; Kim, C.; Bartie, L. J.; Nemeth, M.; Hsu, P. D.; Sercu, T.; Candido, S.; Rives, A.

10.1101/2024.07.01.600583 — synthetic biology — Posted on 2024-07-02

4981 Self-growing protocell models in aqueous two-phase system induced by internal DNA replication reaction

Minagawa, Y.; Yabuta, M.; Su'estugu, M.; Noji, H.

10.1101/2024.07.01.599542 — synthetic biology — Posted on 2024-07-02

4982 HOS15-mediated turnover of PRR7 enhances freezing tolerance

Kim, Y. J.; Kim, W. Y.; Somers, D. E.

10.1101/2024.06.20.599783 — plant biology — Posted on 2024-07-02

4983 Acarbose ameliorates Western diet-induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer's disease

Sonsalla, M. M.; Babygirija, R.; Johnson, M.; Cai, S.; Cole, M.; Yeh, C.-Y.; Grunow, I.; Liu, Y.; Vertein, D.; Calubag, M. F.; Trautman, M. E.; Green, C. L.; Rigby, M. J.; Puglielli, L.; Lamming, D. W.

10.1101/2024.06.27.600472 — physiology — Posted on 2024-07-02

4984 FKBP12-BOUND CALCINEURIN CONTROL TMEM16A ACTIVITY

Guzman-Hernandez, M. L.; Huerta, M.; Lopez-Romero, A. E.; Moran-Zendejas, R.; Betanzos, A.; Perez-Cornejo, P.; ARREOLA, J.

10.1101/2024.06.27.601078 — physiology — Posted on 2024-07-02

4985 SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

Wu, D.; Yang, C.; Yao, Y.; Ma, D.; Lin, H.; Hao, L.; Xin, W.; Ye, K.; Sun, M.; Hu, Y.; Yang, Y.; Zhuang, Z.

10.1101/2023.12.19.572357 — pharmacology and toxicology — Posted on 2024-07-02

4986 The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy

Wang, W.; Li, E.; Zou, J.; Qu, C.; Ayala, J.; Wen, Y.; Islam, M. S.; Weintraub, N. L.; Fulton, D. J.; Liang, Q.; Zhou, J.; Liu, J.; Li, J.; Sun, Y.; Su, H.

10.1101/2024.02.24.581168 — pathology — Posted on 2024-07-02

4987 TEtrimmer: a novel tool to automate the manual curation of transposable elements

Qian, J.; Xue, H.; Ou, S.; Storer, J. M.; Fuertauer, L.; Wildermuth, M. C.; Kusch, S.; Panstruga, R.

10.1101/2024.06.27.600963 — bioinformatics — Posted on 2024-07-02

4988 A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses

Powell, A. E.; Caruso, H.; Park, S.; Chen, J.-L.; O'Rear, J.; Ferrer, B. J.; Walker, A.; Bruening, A.; Hartwig, A.; Ahyong, V.; Dougherty, C. S.; Bowen, R. A.; Ledgerwood, J. E.; Kay, M. S.; Weidenbacher, P. A.- B.; Palanski, B. A.

10.1101/2024.07.01.601243 — biochemistry — Posted on 2024-07-02

4989 Inexperienced bumble bees are poor at securely landing regardless of flower orientation or presence of labellum

McWaters, S. R.; Popp, S.; Rivera, M. D.; Mendoza, F.; Dornhaus, A.

10.1101/2024.06.27.601070 — animal behavior and cognition — Posted on 2024-07-02

4990 A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus) provide evidence of haplotype diversity

Oriowo, T. O.; Chrysostomakis, I.; Martin, S.; Kukowka, S.; Brown, T.; Winkler, S.; Myers, E. W.; Boehne, A.; Stange, M.

10.1101/2023.11.30.569369 — genomics — Posted on 2024-07-02

4991 A High-quality Oxford Nanopore Assembly of the Hourglass Dolphin (Sagmatias cruciger) Genome

McGrath, N.; le Roux, J.; Whibley, A.; Alexander, A.; Stewart, R. O.; Johnstone, M.; Stockin, K. A.; Silander, O. K.

10.1101/2024.05.30.596754 — genomics — Posted on 2024-07-02

4992 Accounting for observation biases associated with counts of young when estimating fecundity: case study on the arboreal-nesting red kite (Milvus milvus)

Sollmann, R.; Adenot, N.; Spakovszky, P.; Windt, J.; Mattsson, B. J.

10.1101/2023.12.01.569571 — ecology — Posted on 2024-07-02

4993 AURA: Automated Universal RNAscope Analysis for high-throughput applications

Descarpentrie, J.; Bernard, F.; Souleyreau, W.; Brisson, L.; Mathivet, T.; Pateras, I. S.; Martin, O. C.; Frisan, T.

10.1101/2024.06.28.601140 — cell biology — Posted on 2024-07-02

4994 A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics

Baniulyte, G.; Wade, J.

10.1101/682021 — microbiology — Posted on 2024-07-02

4995 Comprehensive analysis of the microbial consortium in the culture of flagellate Monocercomonoides exilis

Jimenez-Gonzalez, A.; Treitli, S. C.; Pena-Diaz, P.; Janovska, A.; Benes, V.; Zacek, P.; Hampl, V.

10.1101/2024.02.02.578639 — microbiology — Posted on 2024-07-02

4996 CD28 Shapes T Cell Receptor Signaling by Regulating ZAP70 Activation and Lck Dynamics

Raychaudhuri, K.; Rangu, R.; Ma, A.; Alvinez, N.; Tran, A. D.; Pallikkuth, S.; McIntire, K. M.; Garvey, J. A.; Yi, J.; Samelson, L. E.

10.1101/2024.06.27.601067 — immunology — Posted on 2024-07-02

4997 Antigen specificity shapes antibody functions in tuberculosis.

Miles, J. R.; Lu, P.; Bai, S.; Aguillon-Duran, G.; Rodriguez-Herrera, J.; Gunn, B.; Restrepo, B.; Lu, L.

10.1101/2024.06.03.597169 — immunology — Posted on 2024-07-02

4998 An Atlas of Protein Phosphorylation Dynamics During Interferon Signaling

Busnadiego, I.; Lork, M.; Fernbach, S.; Schiefer, S.; Tsolakos, N.; Hale, B. G.

10.1101/2024.06.28.601147 — immunology — Posted on 2024-07-02

4999 Binocular Listing's Law For Human Eyes' Misaligned Optical Components

Turski, J.

10.1101/2024.06.24.600541 — neuroscience — Posted on 2024-07-02

5000 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action

Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.

10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-02

5001 A central steering circuit in Drosophila

Feng, K.; Khan, M.; Minegishi, R.; Mueller, A.; Van De Poll, M. N.; Swinderen, B. v.; Dickson, B. J.

10.1101/2024.06.27.601106 — neuroscience — Posted on 2024-07-02

5002 Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high field fMRI

Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.

10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-07-02

5003 Comprehensive evaluation of phosphoproteomic-based kinase activity inference

Mueller-Dott, S.; Jaehnig, E. J.; Munchic, K. P.; Jiang, W.; Yaron-Barir, T. M.; Savage, S. R.; Garrido-Rodriguez, M.; Johnson, J. L.; Lussana, A.; Petsalaki, E.; Lei, J. T.; Dugourd, A.; Krug, K.; Cantley, L. C.; Mani, D. R.; Zhang, B.; Saez-Rodriguez, J.

10.1101/2024.06.27.601117 — systems biology — Posted on 2024-07-02

5004 Optimizing alkalinity control in Recirculating Aquaculture Systems (RAS): a dynamic modelling approach

Montjourides, M. A.; Roblitz, S.; Dahle, H.

10.1101/2024.06.28.600787 — systems biology — Posted on 2024-07-02

5005 An expedited qualitative profiling of free amino acids in plant tissues using liquid chromatography-mass spectrometry (LC-MS) in conjunction with MS-DIAL

Kaachra, A.; Tamang, A.; Hallan, V.

10.1101/2024.06.28.601148 — plant biology — Posted on 2024-07-02

5006 Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

Mahmood, S.; Morrice, N. Z.; Thompson, D.; Milanizadeh, S.; Wilson, S.; Whitfield, P. D.; Mcilroy, G. D.; Rochford, J. J.; Mody, N.

10.1101/2024.02.27.582262 — physiology — Posted on 2024-07-02

5007 Structure-Activity Relationship Study Identifies a Novel Lipophilic Amiloride Derivative that Efficiently Kills Chemoresistant Breast Cancer Cells

Hu, M.; Liu, R.; Castro, N.; Loza Sanchez, L.; Learn, J.; Huang, R.; Lam, K. S.; Carraway, K. L.

10.1101/2023.05.25.542364 — pharmacology and toxicology — Posted on 2024-07-02

5008 Atypical contribution of caspase-3 to melanoma cancer cell motility by regulation of coronin 1B activity

Berthenet, K.; Diazzi, S.; Jamard, C.; Stopa, K.; Dragan, S.; Fanfone, D.; Nguyen, T.; Al, N.; Virard, F.; Meurette, O.; Popgeorgiev, N.; Hernandez-Vargas, H.; Ablain, J.; Ichim, G.

10.1101/2024.06.27.601010 — cancer biology — Posted on 2024-07-02

5009 The TissueTractor, a device for applying large strains to tissues and cells for simultaneous high-resolution live cell microscopy.

Yang, J.; Hearty, E.; Wang, Y.; Vijayraghavan, D. S.; Walter, T.; Anjum, S.; Stuckenholz, C.; Cheng, Y.-W.; Balasubramanian, S.; Kwiatkowski, A. V.; Davidson, L. A.

10.1101/2024.06.28.600827 — biophysics — Posted on 2024-07-02

5010 Real-time visualization reveals Mycobacterium tuberculosis ESAT-6 disrupts phagosome via fibril-mediated vesiculation

Koiri, D.; Nandi, M.; PM, A. H.; Bhausaheb, A. J.; Meher, G.; Behura, A.; Kumar, A.; Choudhary, V.; Choubey, S.; Saleem, M.

10.1101/2024.04.19.590309 — biophysics — Posted on 2024-07-02

5011 Towards a More Objective and High-throughput Spheroid Invasion Assay Quantification Method

Mungai, R. W.; Hartman, R. J.; Jolin, G. E.; Piskorowski, K. W.; Billiar, K. L.

10.1101/2024.06.27.600893 — bioengineering — Posted on 2024-07-02

5012 Exploring the genetic and epigenetic underpinnings of early-onset cancers: Variant prioritization for long read whole genome sequencing from family cancer pedigrees

Kramer, M.; Goodwin, S.; Wappel, R.; Borio, M.; Offit, K.; Feldman, D. R.; Stadler, Z. K.; McCombie, W. R.

10.1101/2024.06.27.601096 — genomics — Posted on 2024-07-02

5013 No model to rule them all: a systematic comparison of 83 thermal performance curve models across traits and taxonomic groups

Kontopoulos, D. - G.; Sentis, A.; Daufresne, M.; Glazman, N.; Dell, A. I.; Pawar, S.

10.1101/2023.09.08.556856 — ecology — Posted on 2024-07-02

5014 Effects of microplastics on Daphnia-associated microbiomes in situ and in vitro

Krzynowek, A.; Van de Moortel, B.; Pichler, N.; Vanoverberghe, I.; Lapere, J.; Jenisch, L.; Deloof, D.; Thielemans, W.; Muylaert, K.; Dusselier, M.; Springael, D.; Faust, K.; Decaestecker, E.

10.1101/2024.06.28.601137 — ecology — Posted on 2024-07-02

5015 Enteric Populations of Escherichia coli are Likely to be Resistant to Phages Due to O Antigen Production

Berryhill, B. A.; Burke, K. B.; Fontaine, J.; Brink, C. E.; Harvill, M. G.; Goldberg, D. A.; Konstantinidis, K. T.; Levin, B. R.; Woodworth, M. H.

10.1101/2023.11.08.566299 — microbiology — Posted on 2024-07-02

5016 Target of rapamycin (TOR) regulates CURLY LEAF (CLF) translation in response to environmental stimuli

Yihan, D.; Oubassou, E.-Z.; Hoffmann, E.; Zhang, W.; Uslu, V. V.; Berr, A.

10.1101/2024.06.28.601127 — plant biology — Posted on 2024-07-02

5017 Dissociation between biomechanical stiffness and sEMG activity in trapezius and lumbar skeletal muscles in steady postures

Veraksits, A.; Reinvee, M.; Ereline, J.; Gapeyeva, H.; Kums, T.; Gavronski, G.; Paasuke, M.; Vasar, E.

10.1101/2024.06.27.600991 — biophysics — Posted on 2024-07-02

5018 SCREEN: a graph-based contrastive learning tool to infer catalytic residues and assess mutation tolerance in enzymes

Pan, T.; Bi, Y.; Wang, X.; Zhang, Y.; Webb, G. I.; Gasser, R.; Kurgan, L.; Song, J.

10.1101/2024.06.27.601004 — bioinformatics — Posted on 2024-07-02

5019 Reduced Auditory Perception and Brain Response with Quiet TMS Coil

Murphy, D. L. K.; Koponen, L. M.; Wood, E.; Li, Y.; Bukhari-Parlakturk, N.; Goetz, S. M.; Peterchev, A. V.

10.1101/2024.06.24.600400 — bioengineering — Posted on 2024-07-02

5020 An Autonomous Implantable Device for the Prevention of Death from Opioid Overdose

Ciatti, J. L.; Vazquez-Guardado, A.; Brings, V. E.; Park, J.; Ruyle, B.; Ober, R. A.; McLuckie, A. J.; Talcott, M. R.; Carter, E. A.; Burrell, A. R.; Sponenburg, R. A.; Trueb, J.; Gupta, P.; Kim, J.; Avila, R.; Seong, M.; Slivicki, R. A.; Kaplan, M. A.; Villalpando, B.; Massaly, N.; Montana, M. C.; Pet, M.; Huang, Y.; Moron, J. A.; Gereau, R. W.; Rogers, J. A.

10.1101/2024.06.27.600919 — bioengineering — Posted on 2024-07-02

5021 Evolutionarily conserved principles of ESCRT-III-mediated membrane remodelling revealed by a two-subunit Asgard archaeal system

Souza, D. P.; Espadas, J.; Chaaban, S.; Moody, E. R. R.; Hatano, T.; Balasubramanian, M.; Williams, T. A.; Roux, A.; Baum, B.

10.1101/2024.07.01.601590 — evolutionary biology — Posted on 2024-07-02

5022 Temporal stability of sex ratio distorter prevalence in natural populations of the isopod Armadillidium vulgare

Durand, S.; Pigeault, R.; Giraud, I.; Loisier, A.; Bech, N.; Grandjean, F.; Rigaud, T.; Peccoud, J.; Cordaux, R.

10.1101/2023.11.27.568845 — evolutionary biology — Posted on 2024-07-02

5023 Artificial selection improves pollutant degradation by bacterial communities

Arias-Sanchez, F. I.; Vessman, B.; Haym, A.; Alberti, G.; Mitri, S.

10.1101/2023.07.27.550627 — evolutionary biology — Posted on 2024-07-02

5024 Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

Sur, S.; Kerwin, M.; Pineda, S.; Sansanwal, P.; Sigdel, T. K.; Sirota, M.; Sarwal, M. M.

10.1101/2022.05.13.491826 — cell biology — Posted on 2024-07-02

5025 Induction of neutralising antibodies against conserved rhinovirus capsid protein VP4 depends on presenting VP4 in a virus-like conformation

Kelly, J. T.; Dellosa, G. K.; Newman, J.; Hills, R.; Mohamed, A. A. M.; Aniscenko, J.; Johnston, S. L.; Tuthill, T. J.

10.1101/2024.06.28.601138 — microbiology — Posted on 2024-07-02

5026 WITHDRAWN: Reversing olorofim activity reveals multifactorial drug tolerance in Aspergillus fumigatus

Valero, C.; Mcmanus, M.; Ram Anna Durai, A.; Tindale, J.; Gago, S.; Bromley, M. J.

10.1101/2023.05.20.539046 — microbiology — Posted on 2024-07-02

5027 Pathogenic variants associated with speech/cognitive delay and seizures affect genes with expression biases in excitatory neurons and microglia in developing human cortex

Russ, J. B.; Stone, A. C.; Maney, K.; Morris, L.; Wright, C. F.; Hurst, J. H.; Cohen, J. L.

10.1101/2024.07.01.601597 — neuroscience — Posted on 2024-07-02

5028 Synthesis of alkyl glucosides catalyzed by immobilized α-amylase from Thermotoga maritima

Xolalpa-Villanueva, W.; Ramirez-Amador, F. O.; Olvera, L.; Miranda-Molina, A.; Lopez-Munguia, A.; Saab-Rincon, G.

10.1101/2024.06.28.601278 — biochemistry — Posted on 2024-07-02

5029 Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses

Vasili, E.; Konig, A.; Al-Azzani, M.; Bosbach, C.; Gatzemeier, L. M.; Chegao, A.; Miranda, H. V.; Erskine, D.; Outeiro, T.

10.1101/2024.06.27.600956 — neuroscience — Posted on 2024-07-02

5030 An efficient deep learning method for amino acid substitution model selection

Nguyen Huy, T.; Vinh, L. S.

10.1101/2024.06.27.600948 — bioinformatics — Posted on 2024-07-02

5031 A hypercubic Mk model framework for capturing reversibility in disease, cancer, and evolutionary accumulation modelling

Johnston, I.; Diaz-Uriarte, R.

10.1101/2024.06.27.600959 — bioinformatics — Posted on 2024-07-02

5032 TEtrimmer: a novel tool to automate the manual curation of transposable elements

QIAN, J.; Xue, H.; Ou, S.; Storer, J. M.; Fuertauer, L.; Wildermuth, M. C.; Kusch, S.; Panstruga, R.

10.1101/2024.06.27.600963 — bioinformatics — Posted on 2024-07-02

5033 Encoding of T=1 virus capsid structures through the interfaces of oligomer subcomponents

Jeppesen, M.; Andre, I.

10.1101/2024.06.27.600969 — bioinformatics — Posted on 2024-07-02

5034 Interhemispheric Connectivity of the Human Temporal Lobes

Binder, J. R.; Giraldo-Chica, M.; Mathis, J.; Tong, J.-Q.; Schoenrock, S.; Arpinar, V.; Muftuler, L. T.

10.1101/2024.07.01.601568 — neuroscience — Posted on 2024-07-01

5035 Deep genetic substructure within bonobos

Han, S.; de Filippo, C.; Parra, G.; Meneu, J. R.; Laurent, R.; Frandsen, P.; Hvilsom, C.; Gronau, I.; Marques-Bonet, T.; Kuhlwilm, M.; Andres, A. M.

10.1101/2024.07.01.601523 — evolutionary biology — Posted on 2024-07-01

5036 Dynamics of positional information in the vertebrate neural tube

Markovic, A.; Briscoe, J.; Page, K. M.

10.1101/2024.07.01.601514 — developmental biology — Posted on 2024-07-01

5037 The Potent PHL4 Transcription Factor Effector Domain Contains Significant Disorder

Fonda, B. D.; Murray, D. T.

10.1101/2024.06.27.601048 — biophysics — Posted on 2024-07-01

5038 Phage display profiling of CDR3β loops enables machine learning predictions of NY-ESO-1 specific TCRs

Croce, G.; Lani, R.; Tardivon, D.; Bobisse, S.; de Tiani, M.; Bragina, M.; Perez, M. A.; Schmidt, J.; Guillame, P.; Zoete, V.; Harari, A.; Rufer, N.; Hebeisen, M.; Dunn, S.; Gfeller, D.

10.1101/2024.06.27.600973 — bioinformatics — Posted on 2024-07-01

5039 Leveraging Basecaller's Move Table to Generate a Lightweight k-mer Model

Samarakoon, H.; Kei Wan, Y.; Parameswaran, S.; Göke, J.; Gamaarachchi, H.; Deveson, I. W.

10.1101/2024.06.30.601452 — bioinformatics — Posted on 2024-07-01

5040 TCRfinder: Improved TCR virtual screening for novel antigenic peptides with tailored language models

Li, Y.; Zhang, C.; Zhang, X.; Zhang, Y.

10.1101/2024.06.27.601008 — bioinformatics — Posted on 2024-07-01

5041 Deep Learning-Based Classification of CRISPR Loci Using Repeat Sequences

Liao, X.; Li, Y.; Wu, Y.; Li, X.; Shang, X.

10.1101/2024.06.27.601093 — bioinformatics — Posted on 2024-07-01

5042 Efficient Generation of SOCS2 Knock-out Sheep by Electroporation of CRISPR-Cas9 Ribonucleoprotein Complex with Dual-sgRNAs.

Mahdi, A. K.; Fitzpatrick, D. S.; Hagen, D. E.; McNabb, B. R.; Urbano, T.; Muir, W. M.; Werry, N.; Van Eenennaam, A. L.; Medrano, J. F.; ROSS, P. J.

10.1101/2024.06.30.601433 — bioengineering — Posted on 2024-07-01

5043 Large-Scale Comparative Transcriptomic Analysis of CHO Cell Functional Adaptation to Recombinant Monoclonal Antibody Production

Alexandru-Crivac, C. N.; Cartwright, J. F.; Taylor, R. M.; Sweeney, B. M.; Feary, M.; Chathoth, K. T.; Fabian, D. K.; Allsopp, H.; Brown, A. J.; James, D. C.

10.1101/2024.06.27.600995 — bioengineering — Posted on 2024-07-01

5044 Down regulation of Engase in Caenorhabditis elegans may improve its stresses adaptivity

Lu, X.; Tong, Y.; Wu, M.; Lyu, S.; Fan, J.; Zheng, J.; Zou, L.; Shen, D.; Rao, L.; Hou, L.; Chen, C.; Cheng, X.; Sun, G.; Shao, Z.; Chen, L.

10.1101/2024.07.01.601486 — biochemistry — Posted on 2024-07-01

5045 A stabilized MERS-CoV spike ferritin nanoparticle vaccine elicits robust and protective neutralizing antibody responses

Powell, A. E.; Caruso, H.; Park, S.; Chen, J.-L.; O'Rear, J.; Ferrer, B. J.; Walker, A.; Bruenig, A.; Hartwig, A.; Ahyong, V.; Dougherty, C. S.; Bowen, R. A.; Ledgerwood, J. E.; Kay, M. S.; Weidenbacher, P. A.- B.; Palanski, B. A.

10.1101/2024.07.01.601243 — biochemistry — Posted on 2024-07-01

5046 Streamlined screening platforms lead to the discovery of pachysiphine synthase from Tabernanthe iboga

Kamileen, M. O.; Nakamura, Y.; Luck, K.; Heinicke, S.; Hong, B.; Colinas, M.; Lichman, B. R.; O'Connor, S. E.

10.1101/2024.06.30.601415 — biochemistry — Posted on 2024-07-01

5047 Inhibition of serine racemase prevents diabetic retinopathy

Jiang, H.; Zhou, P.; Jiang, X.; wu, X.; Mao, Y.; Liu, S.; Tang, S.; Zhou, J.; Zhang, Z.; Ren, B.; Shan, G.; Qu, J.; Wu, S.

10.1101/2024.06.30.601441 — biochemistry — Posted on 2024-07-01

5048 Multi-sample non-negative spatial factorization

Wang, Y.; Woyshner, K.; Sriworarat, C.; Stein-O'Brien, G.; Goff, L. A.; Hansen, K. D.

10.1101/2024.07.01.599554 — genomics — Posted on 2024-07-01

5049 The Amphibian Genomics Consortium: advancing genomic and genetic resources for amphibian research and conservation

Kosch, T. A.; Torres-Sanchez, M.; Liedtke, H. C.; Summers, K.; Yun, M. H.; Crawford, A. J.; Maddock, S. T.; Ahammed, M. S.; Araujo, V. L. N.; Vincenzo Bertola, L.; Bucciarelli, G.; Carne, A.; Carneiro, C. M.; Chan, K. O.; Chen, Y.; Crottini, A.; da Silva, J. M.; Denton, R. D.; Dittrich, C.; Espregueira Themudo, G.; Farquharson, K. A.; Forsdick, N. J.; Gilbert, E.; Che, J.; Katzenback, B. A.; Kotharambath, R.; Levis, N. A.; Marquez, R.; Mazepa, G.; Mulder, K. P.; Muller, H.; O'Connell, M. J.; Orozco-terWengel, P.; Palomar, G.; Petzold, A.; Pfennig, D. W.; Pfennig, K. S.; Reichert, M. S.; Robert

10.1101/2024.06.27.601086 — genomics — Posted on 2024-07-01

5050 Estimating allele frequencies, ancestry proportions and genotype likelihoods in the presence of mapping bias

Günther, T.; Schraiber, J. G.

10.1101/2024.07.01.601500 — evolutionary biology — Posted on 2024-07-01

5051 Muskelin acts as a substrate receptor of the highly regulated Drosophila CTLH E3 ligase during the maternal-to-zygotic transition

Briney, C. A.; Henriksen, J. C.; Lin, C.; Jones, L. A.; Benner, L.; Rains, A. B.; Gutierrez, R.; Gafken, P. R.; Rissland, O.

10.1101/2024.06.28.601265 — developmental biology — Posted on 2024-07-01

5052 Identification of mCMQ069, a novel antimalarial with potential for a single-dose cure and/or 28-day chemoprevention

Gupta, A. K.; Pedroarena, J.; Nazarian, A.; Antonova-Koch, J.; Weiss, F.; Kumpornsin, K.; Chi, V.; Woods, A. K.; Lee, K.-J.; Joseph, S. B.; Li, S.; Brittain, J.; Hostos, E. D.; Duffy, J.; Cooper, A.; Schultz, P. G.; McNamara, C. W.; Chatterjee, A. K.

10.1101/2024.07.01.601566 — microbiology — Posted on 2024-07-01

5053 Human erythroid progenitors express antigen presentation machinery

Clements, R. L.; Kennedy, E. A.; Song, D.; Campbell, A.; An, H. H.; Amses, K. R.; Miller-Ensminger, T.; Addison, M. M.; Eisenlohr, L. C.; Chou, S. T.; Jurado, K. A.

10.1101/2024.06.27.601047 — immunology — Posted on 2024-07-01

5054 Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica

Adem, E.; Cruz Cervera, E.; Yizengaw, E.; Takele, Y.; Shorter, S.; Cotton, J.; Getti, G.; Kropf, P.

10.1101/2024.06.27.601019 — immunology — Posted on 2024-07-01

5055 Sulfur Amino Acid Restriction Enhances Exercise Capacity in Mice by Boosting Fat Oxidation

Mann, C. G.; MacArthur, M. R.; Zhang, J.; Gong, S.; AbuSalim, J. E.; Hunter, C. J.; Lu, W.; Agius, T.; Longchamp, A.; Allagnat, F.; Rabinowitz, J.; Mitchell, J. R.; De Bock, K.; Mitchell, S. J.

10.1101/2024.06.27.601041 — physiology — Posted on 2024-07-01

5056 Interspecies interactions alter the antibiotic sensitivity of Pseudomonas aeruginosa

Koumans, C. I. M.; Tandar, S. T.; Liakopoulos, A.; van Hasselt, J. G. C.

10.1101/2024.06.27.601049 — pharmacology and toxicology — Posted on 2024-07-01

5057 PARP14 mediated SQSTM1/p62 cysteine ADP-ribosylation is counteracted by the SARS-CoV-2 macrodomain

Kubon, D.; Leslie Pedrioli, D. M.; Hottiger, M. O.

10.1101/2024.06.29.601315 — molecular biology — Posted on 2024-07-01

5058 In Vitro Generation and Characterization of The Wu Syndrome Model That Causes Mental Retardation in Neural Cell Lines

Karaman, S. S.; Sevik, T.; Akdemir, S.; Bilgin, B.; Karadeli, E.; Yalcin, D.; Baran, B.; Gelsin, B.; Budaklar, B.; Sert, B.; Gulden, G.; Tastan, C.

10.1101/2024.07.01.601494 — molecular biology — Posted on 2024-07-01

5059 Gene body methylation buffers noise in gene expression in plants

Zastapilo, J.; Emmerson, R. A.; Mikheeva, L. A.; Catoni, M.; Bechtold, U.; Zabet, N. R.

10.1101/2024.07.01.601483 — molecular biology — Posted on 2024-07-01

5060 MeCP2 Interacts with the Super Elongation Complex to Regulate Transcription

Sonn, J. Y.; Kim, W.; Iwanaszko, M.; Aoi, Y.; Li, Y.; Parkitny, L.; Brissette, J. L.; Weiner, L.; Al-Ramahi, I.; Botas, J.; Shilatifard, A.; Zoghbi, H. Y.

10.1101/2024.06.30.601446 — molecular biology — Posted on 2024-07-01

5061 Local chromatin decompaction shapes mitotic chromosome landscape

Tashiro, S.; Tanizawa, H.; Noma, K.-i.

10.1101/2024.06.30.601459 — molecular biology — Posted on 2024-07-01

5062 OPUS-TOMO: Deep Learning Framework for Structural Heterogeneity Analysis in Cryo-electron Tomography

Luo, Z.; Wang, Q.; Ma, J.

10.1101/2024.06.30.601442 — molecular biology — Posted on 2024-07-01

5063 Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall

Bekirian, C.; Valsecchi, I.; Bachellier-Bassi, S.; Scandola, C.; Guijarro, J. I.; Chauvel, M.; Mourer, T.; Gow, N.; Aimanianda Bopaiah, V. K.; d'Enfert, C.; Fontaine, T.

10.1101/2024.06.30.601427 — microbiology — Posted on 2024-07-01

5064 Rational Design of Frontline Institutional Phage Cocktail for the Treatment of Nosocomial Enterobacter cloacae Complex Infections

Subedi, D.; Gordillo Altamirano, F. L.; Deehan, R.; Perera, A.; Patwa, R.; Kostoulias, X.; Korneev, D.; Blakeway, L.; Wiesnewski, J.; Macesic, N.; Peleg, A. Y. L.; Barr, J. J.

10.1101/2024.06.30.601436 — microbiology — Posted on 2024-07-01

5065 Porphyromonas gingivalis activates Heat-Shock-Protein 27 to drive a LC3C-specific pro-bacterial form of select autophagy that is redox sensitive for intracellular survival in human gingival mucosa

Wellslager, B.; Roberts, J.; Chowdhury, N.; Madan, L.; Orellana, E.; Yilmaz, O.

10.1101/2024.07.01.601539 — microbiology — Posted on 2024-07-01

5066 High Throughput Repurposing Screen Reveals Compounds with Activity Against Toxoplasma gondii Bradyzoites

Uddin, T.; Xia, J.; Fu, Y.; McNamara, C. W.; Chatterjee, A. K.; Sibley, L. D.

10.1101/2024.07.01.601569 — microbiology — Posted on 2024-07-01

5067 Essential Roles of RodA Peptidoglycan Polymerase and PBP2 Transpeptidase in Expression of Cell Wall-Spanning Supramolecular Organelles and Modulating Salmonella Virulence

Doble, A. C.; Gollan, B. C.; Clark-Corrigall, J. L.; Bulmer, D.; Daniel, R. A.; Mastroeni, P.; Khan, C. M. A.

10.1101/2024.07.01.601524 — microbiology — Posted on 2024-07-01

5068 Differential action modes of Neutrophil Extracellular Trap-targeted drugs define T cell responses in SARS-CoV-2 infection.

Bonilha, C. S.; Veras, F. P.; Ramos, A. d. S.; Gomes, G. F.; Lemes, R. M. R.; Arruda, E.; Alves-Filho, J. C.; Cunha, T. M.; Cunha, F. d. Q.

10.1101/2024.06.30.601403 — immunology — Posted on 2024-07-01

5069 Assessing the predictive value of peak alpha frequency for the sensitivity to pain

May, E. S.; Tiemann, L.; Gil Avila, C. S.; Bott, F. S.; Hohn, V.; Gross, J.; Ploner, M.

10.1101/2024.06.27.600974 — neuroscience — Posted on 2024-07-01

5070 Proteomic analysis of the TDP-43-associated insoluble fraction from NEFH-TDP-43 mouse brain suggests sustained stress granule formation, CLUH granule recruitment and impaired mitochondrial metabolism

Dunlop, F.; Mason, S.; Tsitaknou, S.; Russell, A. P.

10.1101/2024.05.23.595607 — neuroscience — Posted on 2024-07-01

5071 Dual roles of idling moments in past and future memories

Inokuchi, K.; Ghandour, K.; Haga, T.; Ohkawa, N.; FUNG, C. C. A.; Nomoto, M.; Fayed, M. R.; Asai, H.; Sato, M.; Fukai, T.

10.1101/2024.06.27.600961 — neuroscience — Posted on 2024-07-01

5072 Metabolic mode estimated by breathing reflects long-term motor memory

Hayashi, T.; Nakano, N.; Washino, S.; Murai, A.

10.1101/2024.06.27.600911 — neuroscience — Posted on 2024-07-01

5073 Disturbance of the Sense of Agency in Obsessive-Compulsive Disorder and its Modulation by Social Context

Roth, M. J.; Lindner, A.; Fallgatter, A. J.; Wittorf, A.; Jusyte, A.

10.1101/2024.06.27.600968 — neuroscience — Posted on 2024-07-01

5074 PRDM16-DT is a Brain and Astrocyte-Specific lncRNA Implicated in Alzheimers Disease

Schroeder, S.; Fuchs, U.; GIsa, V.; Pena, T.; Krueger, D. M.; Hempel, N.; Burkhardt, S.; Salinas-Riester, G.; Schuetz, A.-L.; Delalle, I.; Sananbenesi, F.; Fischer, A.

10.1101/2024.06.27.600964 — neuroscience — Posted on 2024-07-01

5075 Mitochondrial maintenance is involved in the exceptional longevity of reproductive queens of the eusocial ant Lasius niger

Kervella, M.; Bertile, F.; Granger-Farbos, A.; Pinson, B.; Schmitt, A.; Quque, M.; Bouillaud, F.; Criscuolo, F.

10.1101/2024.06.27.600950 — physiology — Posted on 2024-07-01

5076 Reversible control of kinase signaling through chemical-induced dephosphorylation

Hu, Q.; Sun, Y.; Zhou, R.; Hu, J.; Feng, S.

10.1101/2024.06.27.600945 — cancer biology — Posted on 2024-07-01

5077 Hydrogels for Local and Sustained Delivery of Bacteriophages to Treat Wound Infections

10.1101/2024.05.07.593005 — bioengineering — Posted on 2024-07-01

5078 Extended-depth of field random illumination microscopy, EDF-RIM, provides super-resolved projective imaging

Mazzella, l.; Mangeat, T.; Giroussens, G.; Rogez, B.; Li, H.; Creff, J.; Saadaoui, m.; Martins, C.; Labouesse, S.; Idier, J.; Galland, F.; Allain, M.; Sentenac, A.; LeGoff, L.

10.1101/2023.10.30.564754 — bioengineering — Posted on 2024-07-01

5079 Compromising tyrosine hydroxylase function establishes a delusion-like temporal profile of reinforcement by dopamine neurons in Drosophila

Amin, F.; Koenig, C.; Zhang, J.; Kalinichenko, L. S.; Koenigsmann, S.; Brunsberg, V.; Riemensperger, T. D.; Mueller, C. P.; Gerber, B.

10.1101/2024.06.27.600982 — animal behavior and cognition — Posted on 2024-07-01

5080 Genomic Evidence of Fisheries Induced Evolution in Eastern Baltic cod

Han, K. Y.; Brennan, R. S.; Monk, C. T.; Jentoft, S.; Helmerson, C.; Dierking, J.; Huessy, K.; Kokubun, E. E.; Fuss, J.; Krause-Kyora, B.; Thomsen, T. B.; Heredia, B. D.; Reusch, T. B. H.

10.1101/2024.06.27.601002 — evolutionary biology — Posted on 2024-07-01

5081 Characterizing the speed and severity of mountain pine beetle spread under climate change with a mechanistic model

Brush, M.; Lewis, M. A.

10.1101/2024.06.27.601084 — ecology — Posted on 2024-07-01

5082 Eruptive insect outbreaks from endemic populations under climate change

Brush, M.; Lewis, M. A.

10.1101/2024.06.27.601089 — ecology — Posted on 2024-07-01

5083 Crk mediates Csk-Hippo signaling independently of Yap tyrosine phosphorylation to induce cell extrusion

Hannan, A.; Wang, Q.; Wu, Y.; Makrides, N.; Qu, X.; Mao, J.; Que, J.; Cardoso, W. V.; Zhang, X.

10.1101/2024.06.27.601065 — developmental biology — Posted on 2024-07-01

5084 Burst-dependent Thalamocortical Dynamics Underlie Perceptual Awareness

Whyte, C. J.; Munn, B. R.; Aru, J.; Larkum, M.; John, Y.; Muller, E. J.; Shine, J. M.

10.1101/2023.07.13.548934 — neuroscience — Posted on 2024-07-01

5085 Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action

Wu, P.; Becker, F. B.; Ogelman, R.; Camci, E.; Linbo, T. H.; Simon, J. A.; Rubel, E. W.; Raible, D.

10.1101/2024.05.30.596537 — neuroscience — Posted on 2024-07-01

5086 Functional lung imaging identifies peripheral ventilation changes in mice with muco-obstructive lung disease

Reyne, N.; Smith, R.; Cmielewski, P.; Eikelis, N.; Nilsen, K.; Louise, J.; Duerr, J.; Mall, M. A.; Lawrence, M.; Parsons, D.; Donnelley, M.

10.1101/2024.06.27.600946 — physiology — Posted on 2024-07-01

5087 Challenging the Conventional Treatment Initiation Paradigm: Early Detection of Irreversible Cellular Damage in Cardiac Biopsies of Fabry Disease Before the Formation of Gb3 Inclusion Bodies

Lee, C. L.; Chen, P.-S.; Lu, Y.-Y.; Chiang, Y.-T.; Yen, C.-T.; Huang, C.-Y.; Cheng, Y.-F.; Lin, H.-Y.; Chen, Y.-R.; Niu, D.-M.

10.1101/2024.06.28.601296 — pathology — Posted on 2024-07-01

5088 PIKfyve controls dendritic cell function and tumor immunity

Choi, J. E.; Qiao, Y.; Kryczek, I.; Yu, J.; Gurkan, J.; Bao, Y.; Gondal, M.; Tien, J. C.-Y.; Maj, T.; Yazdani, S.; Parolia, A.; Xia, H.; Zhou, J.; Wei, S.; Grove, S.; Vatan, L.; Lin, H.; Li, G.; Zheng, Y.; Zhang, Y.; Cao, X.; Su, F.; Wang, R.; He, T.; Cieslik, M.; Green, M. D.; Zou, W.; Chinnaiyan, A. M.

10.1101/2024.02.28.582543 — cancer biology — Posted on 2024-07-01

5089 Latent mitotic vulnerability of AML cells induced by therapeutic agents

Niikura, R.; Yabushita, T.; Yamamoto, S.; Suzuki, H.; Fukuyama, M.; Hata, S.; Goyama, S.; Kitamura, T.; Chinen, T.; Kitagawa, D.

10.1101/2024.06.27.600939 — cancer biology — Posted on 2024-07-01

5090 RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway

Huang, F.; Dai, Z.; Yu, J.; Wang, K.; Chen, C.; Chen, D.; Zhang, J.; Zhao, J.; Zhang, W.; Qi, Y.; Wang, Y.; Li, X.; Li, M.

10.1101/2024.01.03.574004 — cancer biology — Posted on 2024-07-01

5091 A Message Passing Framework for Precise Cell State Identification with scClassify2

Ding, W.; Cao, Y.; Fu, X.; Torkel, M.; Yang, J.

10.1101/2024.06.26.600770 — bioinformatics — Posted on 2024-07-01

5092 SLUR(M)-py: A SLURM Powered Pythonic Pipeline for Parallel Processing of 3D (Epi)genomic Profiles

Roth, C. J. N.; Venu, V.; Bacot, S.; Steadman, C. R.; Starkenburg, S. R.

10.1101/2024.05.18.594827 — bioinformatics — Posted on 2024-07-01

5093 Parallelism between phylogeny and ontogeny

Bergman, J.; Bakaric, R.; Brcic-Kostic, K.

10.1101/2024.06.27.600990 — evolutionary biology — Posted on 2024-07-01

5094 Detecting epidemic-driven selection: a simulation-based tool to optimize sampling design and analysis strategies

Santander, C. G.; Moltke, I.

10.1101/2024.06.27.601009 — evolutionary biology — Posted on 2024-07-01

5095 Detecting branching rate heterogeneity in multifurcating trees with applications in lineage tracing data

Feder, A. F.; Gao, Y.

10.1101/2024.06.27.601073 — evolutionary biology — Posted on 2024-07-01

5096 Local selection shaped the diversity of European maize landraces

Takou, M.; Schulz, K.; Stetter, M. G.

10.1101/2024.06.07.597898 — evolutionary biology — Posted on 2024-07-01

5097 Polyphyletic domestication and inter-lineage hybridization magnified genetic diversity of cultivated melon, Cucumis melo L.

TANAKA, K.; Shigita, G.; Dung, T. P.; Nhi, P. T. P.; Takahashi, M.; Monden, Y.; Nishida, H.; Ishikawa, R.; Kato, K.

10.1101/2024.06.27.601017 — evolutionary biology — Posted on 2024-07-01

5098 Flexible movement kernel estimation in habitat selection analyses with generalized additive models

Arce Guillen, R.; Pohle, J.; Jeltsch, F.; Roeleke, M.; Reineking, B.; Klappstein, N.; Schlägel, U.

10.1101/2024.06.27.600970 — ecology — Posted on 2024-07-01

5099 Long-term effects of ocean acidification and its interaction with warming on calcifying organisms and their associated microbiome: bryozoans as emerging sentinels of global change?

Figuerola, B.; Capdevila, P.; Cerda-Domenech, M.; Garrabou, J.; Mirasole, A.; Bassols, P.; del Campo, J.; Teixido, N.

10.1101/2024.06.28.601120 — ecology — Posted on 2024-07-01

5100 Ecologically and economically sustainable level of timber harvesting in boreal forests - defining the safe operating space for forest use

Mönkkönen, M.; Blattert, C.; Cours, J.; Duflot, R.; Elo, M.; Eyvindson, K.; Kouki, J.; Trivino, M.; Burgas, D.

10.1101/2024.06.27.600997 — ecology — Posted on 2024-07-01

5101 Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival

Goswami, M. T.; Weh, E.; Subramanya, S.; Weh, K. M.; Durumutla, H. B.; Hager, H.; Miller, N.; Chaudhury, S.; Andren, A.; Sajjakulnukit, P.; Zhang, L.; Besirli, C. G.; Lyssiotis, C. A.; Wubben, T. J.

10.1101/2024.03.26.582525 — cell biology — Posted on 2024-07-01

5102 Concurrent Joint Contact in Anterior Cruciate Ligament Injury induces cartilage micro-injury and subchondral bone sclerosis, resulting in knee osteoarthritis

Takahata, K.; Lin, Y.-Y.; Osipov, B.; Arakawa, K.; Enomoto, S.; Christiansen, B. A.; Kokubun, T.

10.1101/2024.05.08.593114 — molecular biology — Posted on 2024-07-01

5103 Some like it hot: efficiency of the type III secretion system and activation of plant defenses have multiple thermosensitive behaviors in the Pseudomonas syringae complex

Caullireau, E.; Danzi, D.; Tempo, V. M.; Pandolfo, M.; Morris, C. E.; Vandelle, E.

10.1101/2024.05.31.596889 — microbiology — Posted on 2024-07-01

5104 A phosphorylation signal activates genome-wide transcriptional control by BfmR, the global regulator of Acinetobacter resistance and virulence.

Raustad, N.; Dai, Y.; Iinishi, A.; Mohapatra, A.; Soo, M. W.; Hay, E.; Hernandez, G. M.; Geisinger, E.

10.1101/2024.06.16.599214 — microbiology — Posted on 2024-07-01

5105 How predictability and individual alpha frequency shape memory: insights from the N400

Jano, S. L.; Chatburn, A.; Cross, Z. R.; Schlesewsky, M.; Bornkessel-Schlesewsky, I.

10.1101/2023.10.25.564081 — neuroscience — Posted on 2024-07-01

5106 Electrical brain activations in preadolescents during a probabilistic reward-learning task reflect cognitive processes and behavioral strategy.

Chung, Y. S.; van den Berg, B.; Roberts, K. C.; Bagdasarov, A.; Woldorff, M. G.; Gaffrey, M. S.

10.1101/2023.10.16.562326 — neuroscience — Posted on 2024-07-01

5107 Comparing Automated Subcortical Volume Estimation Methods; Amygdala Volumes Estimated by FSL and FreeSurfer Have Poor Consistency

Sadil, P.; Lindquist, M. A.

10.1101/2024.03.07.583900 — neuroscience — Posted on 2024-07-01

5108 APOE, Immune Factors, Sex, and Diet Interact to Shape Brain Networks in Mouse Models of Aging

Winter, S.; Mahzarnia, A.; Anderson, R. J.; Han, Z. Y.; Tremblay, J. J.; Stout, J. A.; Moon, H. S.; Marcellino, D.; Dunson, D.; Badea, A.

10.1101/2023.10.04.560954 — neuroscience — Posted on 2024-07-01

5109 Social Conformity Updates the Neural Representation of Facial Attractiveness

Chen, D.; Yao, Z.; Liu, J.; Wu, H.; Hu, X.

10.1101/2023.02.08.527779 — neuroscience — Posted on 2024-07-01

5110 "Tiny Biome Tales": a gamified review about the influence of lifestyle choices on the human microbiome

Schweitzer, M.; Wlasak, M.; Wassermann, B.; Marcher, F.; Poglitsch, C.; Pirker, J.; Berg, G.

10.1101/2024.06.29.601357 — scientific communication and education — Posted on 2024-07-01

5111 Cytokinin-inducible DIRIGENT13 involved in lignan synthesis and ROS accumulation promotes root growth and abiotic stress tolerance in Arabidopsis

Melnikava, A.; Perreau, F.; Paniagua, C.; Cheng, S.-C.; Huang, L.-M.; Ubogoeva, E.; Zemlyanskaya, E.; Yang, Y.-L.; Mouille, G.; Arnaud, D.; Hejatko, J.

10.1101/2024.06.25.600713 — plant biology — Posted on 2024-07-01

5112 Alasemenia, the earliest ovule with three wings and without cupule

Wang, D.; Yang, J.; Liu, L.; Zhou, Y.; Xu, P.; Qin, M.; Huang, P.

10.1101/2023.10.11.561822 — paleontology — Posted on 2024-07-01

5113 Gravitational effect on the cell in bio-fluid suspension

Murali, A.; Sarkar, R.

10.1101/2024.04.22.590537 — biophysics — Posted on 2024-07-01

5114 Leveraging Sentence-BERT for Advanced MicroRNA Target Predictions in Diseases

Chen, B.; Huang, H.-Y.

10.1101/2024.05.17.594604 — bioinformatics — Posted on 2024-07-01

5115 IL-6 SIGNALING EXACERBATES HALLMARKS OF CHRONIC TENDON DISEASE BY STIMULATING REPARATIVE FIBROBLASTS

Stauber, T.; Moschini, G.; Hussien, A. A.; Jaeger, P. K.; De Bock, K.; Snedeker, J. G.

10.1101/2023.02.13.528273 — bioengineering — Posted on 2024-07-01

5116 A split-belt instrumented treadmill with uneven terrain

Kuo, A. D.; Hosseini-Yazdi, S. S.

10.1101/2024.06.28.601238 — bioengineering — Posted on 2024-07-01

5117 Links between behaviour and resistances to acute hyperthermia and hypoxia using rainbow trout isogenic lines

Lagarde, H.; LALLIAS, D.; Phocas, F.; Goardon, L.; Bideau, M.; Guyvarc'h, F.; Labbe, L.; Dupont-Nivet, M.; Cousin, X.

10.1101/2023.10.19.563047 — animal behavior and cognition — Posted on 2024-07-01

5118 Single-cell analysis of human diversity in circulating immune cells

Kock, K. H.; Tan, L. M.; Han, K. Y.; Ando, Y.; Jevapatarakul, D.; Chatterjee, A.; Lin, Q. X. X.; Buyamin, E. V.; Sonthalia, R.; Rajagopalan, D.; Tomofuji, Y.; Sankaran, S.; Park, M.-S.; Abe, M.; Chantaraamporn, J.; Furukawa, S.; Ghosh, S.; Inoue, G.; Kojima, M.; Kouno, T.; Lim, J.; Myouzen, K.; Nguantad, S.; Oh, J.-M.; Rayan, N. A.; Sarkar, S.; Suzuki, A.; Thungsatianpun, N.; Venkatesh, P. N.; Moody, J.; Nakano, M.; Chen, Z.; Tian, C.; Zhang, Y.; Tong, Y.; Tan, C. T. Y.; Tizazu, A. M.; SG10K_Health Consortium, ; Loh, M.; Hwang, Y. Y.; Ho, R. C.; Larbi, A.; Ng, T. P.; Won, H.-H.; Wright, F. A.

10.1101/2024.06.30.601119 — genomics — Posted on 2024-07-01

5119 Skull evolution and lineage diversification in endemic Malagasy carnivorans

Law, C.; Linden, T.; Flynn, J. J.

10.1101/2024.03.25.586658 — evolutionary biology — Posted on 2024-07-01

5120 The Molecules Gateway: a homogeneous, searchable database of 150k annotated molecules from Actinomycetes

Simone, M.; Iorio, M.; Monciardini, P.; Santini, M.; Cantu, N.; Tocchetti, A.; Serina, S.; Brunati, C.; Vernay, T.; Gentile, A.; Aracne, M.; Cozzi, M.; van der Hooft, J.; Sosio, M.; Donadio, S.; Maffioli, S. I.

10.1101/2024.06.28.601135 — microbiology — Posted on 2024-07-01

5121 Microglial MyD88-dependent pathways are regulated in a sex specific manner in the context of HMGB1-induced anxiety

Rawls, A.; Nguyen, D.; Dziabis, J.; Clark, M.; Anbarci, D.; Bilbo, S. D.; Dzirasa, K.

10.1101/2024.04.22.590482 — neuroscience — Posted on 2024-07-01

5122 Central nucleus of the amygdala to medial prefrontal cortex 5-HTergic neural circuit modulates the recovery of consciousness during sevoflurane anesthesia

Wang, Y.; Yang, Y.; Wu, Y.; Xu, X.; Xu, Q.; Zhang, Z.; Di, X.; Zhang, H.

10.1101/2024.06.19.599720 — neuroscience — Posted on 2024-07-01

5123 The spiking output of the mouse olfactory bulb encodes large-scale temporal features of natural odor environments

Lewis, S. M.; Suarez, L. M.; Rigolli, N.; Franks, K.; Steinmetz, N. A.; Gire, D. H.

10.1101/2024.03.01.582978 — neuroscience — Posted on 2024-07-01

5124 Cancer vaccine attenuates carcinogen induced head and neck cancer with impaired early T cell response

Kono, M.; Rokugo, M.; Quadarella, J. D.; Saito, S.; Komatsuda, H.; Fu, C.; Woo, S.-B.; Egloff, A. M.; Uppaluri, R.

10.1101/2024.06.26.600828 — cancer biology — Posted on 2024-07-01

5125 A single theory for the evolution of sex chromosomes and the two rules of speciation

Lenormand, T.; Roze, D.

10.1101/2024.03.18.585601 — evolutionary biology — Posted on 2024-07-01

5126 Novel Mechanism for Tubular Injury in Nephropathic Cystinosis

Sur, S.; Kerwin, M.; Pineda, S.; Sansanwal, P.; Sigdel, T. K.; Sirota, M.; Sarwal, M. M.

10.1101/2022.05.13.491826 — cell biology — Posted on 2024-07-01

5127 Evidence for a role of human blood-borne factors in mediating age-associated changes in molecular circadian rhythms

Schwarz, J. E.; Mrcela, A.; Lahens, N. F.; Li, Y.; Hsu, C.; Grant, G.; Skarke, C.; Zhang, S. L.; Sehgal, A.

10.1101/2023.04.19.537477 — molecular biology — Posted on 2024-07-01

5128 The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target.

Alharthi, R.; Sueiro-Olivares, M.; Storer, I.; Alshammri, H.; Scott, J.; Al-Shidhani, R.; Fortune-Grant, R.; Bignell, E.; Tabernero, L.; Bromley, M.; Zhao, C.; Amich, J.

10.1101/2024.03.08.582945 — microbiology — Posted on 2024-07-01

5129 Exposure to live saprophytic Leptospira before challenge with a pathogenic serovar prevents severe leptospirosis and promotes kidney homeostasis

Kundu, S.; Shetty, A.; Gomes-Solecki, M.

10.1101/2024.03.01.582981 — immunology — Posted on 2024-07-01

5130 Re-focusing visual working memory during expected and unexpected memory tests

Wang, S.; van Ede, F.

10.1101/2024.05.23.595544 — neuroscience — Posted on 2024-07-01

5131 RNA-Protein Interaction Prediction without High-Throughput Data: An Overview and Benchmark of in silico Tools

Krautwurst, S.; Lamkiewicz, K.

10.1101/2024.06.24.600368 — bioinformatics — Posted on 2024-07-01

5132 Mating preferences act independently on individual elements of visual signals in Heliconius butterflies

Smith, S.; Queste, L.; Wright, D. S.; Bacquet, C.; Merrill, R. M.

10.1101/2023.11.24.568567 — evolutionary biology — Posted on 2024-07-01

5133 PAN deadenylase ensures proper mitosis under conditions of microtubule stress by regulating spindle integrity and promoting cell survival

Verma, J.; He, Z.; Brown, J. A. R.; Dean, P.; Young, B.; Flibotte, S.; Howe, L. J.; Maxwell, C.; Roskelley, C.; Loewen, C.

10.1101/2024.05.01.591760 — cell biology — Posted on 2024-07-01

5134 A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface

Simmons, H. C.; Finney, J.; Kotaki, R.; Adachi, Y.; Moseman, A. P.; Watanabe, A.; Song, S.; Robinson-McCarthy, L. R.; Le Sage, V.; Kuraoka, M.; Moseman, E. A.; Kelsoe, G.; Takahashi, Y.; McCarthy, K. R.

10.1101/2023.12.13.571543 — microbiology — Posted on 2024-07-01

5135 IRF8 configures enhancer landscape in postnatal microglia and directs microglia specific transcriptional programs

Saeki, K.; Pan, R.; Lee, E.; Kurotaki, D.; Ozato, K.

10.1101/2023.06.25.546453 — immunology — Posted on 2024-07-01

5136 A humoral immune response to parasitoid wasps in Drosophila is regulated by JAK/STAT, NF-κB and GATA

Zhou, S. O.; Day, J. P.; Deplancke, B.; Leitao, A. B.; Jiggins, F. M.

10.1101/2024.06.12.598701 — immunology — Posted on 2024-07-01

5137 The Role of Cilia in the Development, Survival, and Regeneration of Hair Cells

Boldizar, H.; Friedman, A.; Stanley, T.; Padilla, M.; Galdieri, J.; Sclar, A.; Stawicki, T. M.

10.1101/2024.04.01.587636 — neuroscience — Posted on 2024-07-01

5138 A side-by-side comparison of variant function measurements using deep mutational scanning and base editing

Sokirniy, I.; Inam, H.; McCandlish, D.; Pritchard, J. R.

10.1101/2024.06.30.601444 — genomics — Posted on 2024-07-01

5139 A Markovian neural barcode representing mesoscale cortical spatiotemporal dynamics.

Culp, J. M.; Ashby, D. M.; George, A.; Teskey, G. C.; Nicola, W.; McGirr, A.

10.1101/2024.06.29.601346 — neuroscience — Posted on 2024-07-01

5140 Behavioral state regulates the dynamics of memory consolidation

Silva, N. T.; Ribeiro, M. I.; Carey, M. R.

10.1101/2024.06.28.601231 — neuroscience — Posted on 2024-07-01

5141 Stimulus selection drives value-modulated somatosensory processing in superior colliculus

Chu, Y. W.; Chinta, S.; Keri, H. V. S.; Beri, S.; Pluta, S. R.

10.1101/2024.06.28.601226 — neuroscience — Posted on 2024-07-01

5142 Human Accelerated Regions regulate gene networks implicated in apical-to-basal neural progenitor fate transitions

Noble, M. A.; Ji, Y.; Yim, K. M.; Yang, J. W.; Morales, M.; Abu-Shamma, R.; Pal, A.; Poulsen, R.; Baumgartner, M.; Noonan, J. P.

10.1101/2024.06.30.601407 — neuroscience — Posted on 2024-07-01

5143 The frontal cortex adjusts striatal integrator dynamics for flexible motor timing

Yang, Z.; Inagaki, M.; Gerfen, C.; Fontolan, L.; Inagaki, H. K.

10.1101/2024.06.29.601348 — neuroscience — Posted on 2024-07-01

5144 Spatiotemporal patterns in cortical development: Age, puberty, and individual variability from 9 to 13 years of age

Bottenhorn, K. L.; Corbett, J. D.; Ahmadi, H.; Herting, M. M.

10.1101/2024.06.29.601354 — neuroscience — Posted on 2024-07-01

5145 Longitudinal trajectories of brain development from infancy to school age and their relationship to literacy development

Turesky, T. K.; Escalante, E.; Loh, M. Y.; Gaab, N.

10.1101/2024.06.29.601366 — neuroscience — Posted on 2024-07-01

5146 Motor adaptation is reduced by symbolic compared to sensory feedback

Chen, Y.; Abram, S. J.; Ivry, R. B.; Tsay, J. S.

10.1101/2024.06.28.601293 — neuroscience — Posted on 2024-07-01

5147 Live-cell RNA imaging with the inactivated endonuclease Csy4 enables new insights into plant virus transport through plasmodesmata

Burnett, D.; Hussein, M.; Barr, Z. K.; Nather, L. N.; Wright, K. M.; TILSNER, J.

10.1101/2024.06.27.601026 — cell biology — Posted on 2024-07-01

5148 Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells

Moerkens, R.; Mooiweer, J.; Smits, E.; Berg, M.; Ramirez Sanchez, A. D.; Modderman, R.; Puschhof, J.; Pleguezuelos-Manzano, C.; Barrett, R. J.; Wijmenga, C.; Jonkers, I. H.; Withoff, S.

10.1101/2024.06.30.601390 — cell biology — Posted on 2024-07-01

5149 Membrane Curvature Promotes ER-PM Contact Formation via Junctophilin-EHD Interactions

Yang, Y.; Valencia, L. A.; Lu, C.-H.; Nakamoto, M. L.; Tsai, C.-T.; Liu, C.; Yang, H.; Zhang, W.; Jahed, Z.; Lee, W.-R.; Santoro, F.; Liou, J.; Wu, J. C.; Cui, B.

10.1101/2024.06.29.601287 — cell biology — Posted on 2024-07-01

5150 A distinct isoform of Msp300/Nesprin organizes the perinuclear microtubule organizing center in adipose cells

Morton, G. M.; Toledo, M. P.; Zheng, Y.; Zheng, C.; Megraw, T. L.

10.1101/2024.06.28.601268 — cell biology — Posted on 2024-07-01

5151 PINK1-G411S mutant increases kinase stability and enhances mitochondrial-linked functions

Goncalves, F. B.; Enguita, F. J.; Morais, V. A.

10.1101/2024.06.28.601304 — cell biology — Posted on 2024-07-01

5152 Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA , a neurodegenerative disease in which the RIβ-L50R variant is expressed

Benjamin-Zukerman, T.; Pane, V.; Safadi-Safa, R.; Solomon, M.; Lev-Ram, V.; Aboraya, M.; Dakwar, A.; Bertinetti, D.; Hoy, A.; Mol, M.; van Swieten, J.; Herberg, F. W.; Maillard, R.; Ilouz, R.

10.1101/2024.06.30.601371 — cell biology — Posted on 2024-07-01

Archive, 2024-07