bioRxiv directory

Kockelkoren, G.; Carstensen, J.; Lauritsen, L.; Kazepidou, E.; Tonnesen, A.; Shuttle, C. G.; Kaas, P. S.; Gupta, A.; Breuer, A.; Rasmussen, S. G. F.; Duffet, L.; Warne, T.; Patriarchi, T.; Tate, C. G.; Uline, M.; Stamou, D.

10.1101/2024.02.28.582451 — biophysics — Posted on 2024-02-29

4 Study of Impacts of Two Types of Cellular Aging on the Yeast Bud Morphogenesis

Tsai, K.; Zhou, Z.; Yang, J.; Xu, Z.; Xu, S.; Zandi, R.; Hao, N.; Chen, W.; Alber, M.

10.1101/2024.02.29.582376 — biophysics — Posted on 2024-02-29

5 stMMR: accurate and robust spatial domain identification from spatially resolved transcriptomics with multi-modal feature representation

Zhang, D.; Yu, N.; Li, W.; Sun, X.; Zou, Q.; Li, X.; Liu, Z.; Yuan, Z.; Zhang, W.; Gao, R.

10.1101/2024.02.22.581503 — bioinformatics — Posted on 2024-02-29

6 Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing

Ng, H. Y.; Adly, A. N.; Whelpley, D. H.; Suhandynata, R. T.; Zhou, H.; Morgan, D. O.

10.1101/2024.02.28.582599 — biochemistry — Posted on 2024-02-29

7 Learning Continuous 2D Diffusion Maps from Particle Trajectories without Data Binning

Kumar, V.; Bryan, J. S.; Rowjeski, A.; Manzo, C.; Presse, S.

10.1101/2024.02.27.582378 — biophysics — Posted on 2024-02-29

8 Defining the most potent osteoinductive culture conditions for MC3T3-E1 cells reveals no implication of oxidative stress or energy metabolism

Semicheva, A.; Ersoy, U.; Vasilaki, A.; Myrtziou, I.; Kanakis, I.

10.1101/2024.02.28.582483 — cell biology — Posted on 2024-02-29

9 β-Hydroxybutyrate promotes basal insulin secretion while decreasing glucagon secretion in mouse and human islets.

Banerjee, R.; Zhu, Y.; Brownrigg, G. P.; Moravcova, R.; Rogalski, J. C.; Foster, L.; Johnson, J. D.; Kolic, J.

10.1101/2024.02.27.582117 — cell biology — Posted on 2024-02-29

10 PfCAP-H is essential for assembly of condensin I complex and karyokinesis during asexual proliferation of Plasmodium falciparum

Gurung, P.; McGee, J. P.; Dvorin, J. D.

10.1101/2024.02.26.582160 — cell biology — Posted on 2024-02-29

11 A single-cell atlas of the murine pancreatic ductal tree identifies novel cell populations with potential implications in pancreas regeneration and exocrine pathogenesis.

Fernandez, A.; Casamitjana, J.; Holguin-Horcajo, A.; Coolens, K.; Mularoni, L.; Pasquali, L.; Bailey-Lundberg, J. M.; Rooman, I.; Wang, Y. J.; Rovira, M.

10.1101/2024.02.26.582044 — cell biology — Posted on 2024-02-29

12 Endothelial features along the pulmonary vascular tree in chronic thromboembolic pulmonary hypertension: distinctive or shared facets?

Verhaegen, J.; Willems, L.; Wagenaar, A.; Spreuwers, R.; Dahdah, N.; Aversa, L.; Verbelen, T.; Delcroix, M.; Quarck, R.

10.1101/2024.02.27.582290 — cell biology — Posted on 2024-02-29

13 Heat shock alters the distribution and in vivo interaction of major nuclear structural proteins, lamin and DNA topoisomerase II, with nucleic acids

Rowinska, M.; Tomczak, A.; Jablonska, J.; Machowska, M.; Piekarowicz, K.; Rzepecki, R.

10.1101/2024.02.28.582469 — cell biology — Posted on 2024-02-29

14 Atlastin-1 regulates endosomal tubulation and lysosomal proteolysis in human cortical neurons

Zlamalova, E.; Rodger, C.; Greco, F.; Kleniuk, J.; Nadadur, A. G.; Kadlecova, Z.; Reid, E.

10.1101/2024.02.29.582512 — cell biology — Posted on 2024-02-29

15 FHOD-1/profilin-mediated actin assembly protect sarcomeres against contraction-induced deformation in C. elegans

Kimmich, M. D.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.

10.1101/2024.02.29.582848 — cell biology — Posted on 2024-02-29

16 Glomerular Elasticity and Gene Expression Patterns Define Two Phases of Alport Nephropathy

Yoon, J.; Liu, Z.; Alaba, M.; Bruggeman, L. A.; Janmey, P.; Arana, C.; Ayenuyo, O.; Medeiros, I.; Eddy, S.; Kretzler, M.; Henderson, J. M.; Naik, A.; Chang, A. N.; Miller, R. T.

10.1101/2024.02.26.582201 — cell biology — Posted on 2024-02-29

17 Metabolic and age-associated epigenetic barriers during direct reprogramming of mouse fibroblasts into induced cardiomyocytes

Santos, F.; Correia, M.; Dias, R.; Bola, B.; Noberini, R.; Ferreira, R. S.; Domingues, P.; Teixeira, J.; Bonaldi, T.; Oliveira, P. J.; Bernardes de Jesus, B.; Bar, C.; Nobrega-Pereira, S.

10.1101/2024.02.28.582570 — cell biology — Posted on 2024-02-29

18 On-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures

Onal, S.; Alkaisi, M. M.; Nock, V.

10.1101/2024.02.28.582630 — cell biology — Posted on 2024-02-29

19 An injury-induced tissue niche shaped by mesenchymal plasticity coordinates the regenerative and disease response in the lung

Jones, D. L.; Morley, M. P.; Li, X.; Yun, Y.; Cardenas-Diaz, F. L.; Li, S.; Zhou, S.; Schaefer, S. E.; Chembazhi, U. V.; Nottingham, A.; Lin, S.; Cantu, E.; Diamond, J. M.; Basil, M. C.; Vaughan, A. E.; Morrisey, E. E.

10.1101/2024.02.26.582147 — cell biology — Posted on 2024-02-29

20 Lipidomic analysis of human TANGO2-deficient cells suggests a lipid imbalance as a cause of TANGO2 deficiency disease

Mehranfar, M.; Asadi, P.; Shokohi, R.; Milev, M. P.; Gamberi, C.; Sacher, M.

10.1101/2024.02.29.581305 — cell biology — Posted on 2024-02-29

21 Doublecortin reinforces microtubules to promote growth cone advance in soft environments

Dema, A.; Charafeddine, R. A.; van Haren, J.; Rahgozar, S.; Viola, G.; Jacobs, K. A.; Kutys, M. L.; Wittmann, T.

10.1101/2024.02.28.582626 — cell biology — Posted on 2024-02-29

22 Comparison of monomeric variants of StayGold

Miyawaki, A.; Shimozono, S.; Ando, R.; Sugiyama, M.; Hirano, M.; Niino, Y.

10.1101/2024.02.28.582207 — bioengineering — Posted on 2024-02-29

23 DELE1 promotes translation-associated homeostasis, growth, and survival in mitochondrial myopathy

Lin, H.-P.; Petersen, J. D.; Gilsrud, A.; Madruga, A.; D'Silva, T. M.; Huang, X.; Shammas, M. K.; Randolph, N. P.; Li, Y.; Jones, D. R.; Pacold, M. E.; Narendra, D.

10.1101/2024.02.29.582673 — cell biology — Posted on 2024-02-29

24 SUMO Promotes DNA Repair Protein Collaboration to Support Alterative Telomere Lengthening in the Absence of PML

Zhao, R.; Xu, M.; Wondisford, A. R.; Lackner, R. M.; Salsman, J.; Dellaire, G.; Chenoweth, D. M.; O'Sullivan, R. J.; Zhao, X.; Zhang, H.

10.1101/2024.02.29.582813 — cell biology — Posted on 2024-02-29

25 Novel Nuclear Roles for Testis-Specific ACTL7A and ACTL7B Supported by In Vivo Characterizations and AI Facilitated In Silico Mechanistic Modeling with Implications for Epigenetic Regulation in Spermiogenesis.

Ferrer, P.; Upadhyay, S.; Cai, J.; Clement, T. M.

10.1101/2024.02.29.582797 — cell biology — Posted on 2024-02-29

26 Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes

Muir, C. F.; Reyes-Aldasoro, C. C.; Ellett, F.; Prajsnar, T.; Ho, Y. X.; Bernut, A.; Loynes, C. A.; Elworthy, S.; Bowden, K. A.; Cadby, A. J.; Prince, L.; King, J. S.; Condliffe, A. M.; Renshaw, S.

10.1101/2024.02.29.582694 — cell biology — Posted on 2024-02-29

27 Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by aging

Molzahn, C.; Kuechler, E.; Nierves, L.; Cole, G.; Wang, J.; Cashman, N.; Karsan, A.; Lange, P. F.; Gsponer, J.; Mayor, T.

10.1101/2024.02.28.582597 — cell biology — Posted on 2024-02-29

28 Sec23IP recruits the Cohen syndrome factor VPS13B/COH1 to ER exit site-Golgiinterface for tubular ERGIC formation

Du, Y.; Fan, X.; Song, C.; Ji, W.

10.1101/2024.02.28.582656 — cell biology — Posted on 2024-02-29

29 Limited Cell-Autonomous Anticancer Mechanisms in Long-Lived Bats

Athar, F.; Zheng, Z.; Riquier, S.; Zacher, M.; Alcock, D.; Galazyuk, A.; Cooper, L. N.; Schountz, T.; Wang, L.; Teeling, E.; Seluanov, A.; Gorbunova, V.

10.1101/2024.02.29.582714 — cell biology — Posted on 2024-02-29

30 Insulin signaling regulates R2 retrotransposon expression to orchestrate transgenerational rDNA copy number maintenance

Nelson, J. O.; Slicko, A.; Raz, A. A.; Yamashita, Y. M.

10.1101/2024.02.28.582629 — cell biology — Posted on 2024-02-29

31 Shugoshin maintains mitotic arrest in response to improper kinetochore-microtubule interactions independent of the Bub1-pH2A axis

Polisetty, S. D.; Bhat, K.; Clark, I.; Hardwick, K. G.; Sanyal, K.

10.1101/2024.02.28.582509 — cell biology — Posted on 2024-02-29

32 Multiple triggers converge to preferential effector coupling in the CB2R through a complex allosteric communication network

Morales-Pastor, A.; Miljus, T.; Stepniewski, T. M.; Ledesma, V.; Heydenreich, F.; Flock, T.; Plouffe, B.; Le Gouill, C.; Duchaine, J.; Guba, W.; Rufer, A.; Grether, U.; Bouvier, M.; Veprintsev, D.; Selent, J.

10.1101/2024.02.27.582279 — cell biology — Posted on 2024-02-29

33 Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP

Meyer, G.; Ferey, J. L. A.; Sanford, J. A.; Fitzgerald, L. S.; Greenberg, A. E.; Svensson, K.; Greenberg, M. J.; Schenk, S.

10.1101/2024.02.27.582179 — cell biology — Posted on 2024-02-29

34 Thymidine Phosphorylase Promotes the Formation of Abdominal Aortic Aneurysm in Mice Fed a Western Diet

Hong, L.; Yue, H.; Cai, D.; DeHart, A.; Toloza-Alvarez, G.; Du, L.; Zhou, X.; Fan, X.; Huang, H.; Chen, S.-Y.; Rahaman, S.; Zhuang, J.; Li, W.

10.1101/2024.02.27.582208 — cell biology — Posted on 2024-02-29

35 MultiMatch: Geometry-Informed Colocalization in Multi-Color Super-Resolution Microscopy

Naas, J.; Nies, G.; Li, H.; Stoldt, S.; Schmitzer, B.; Jakobs, S.; Munk, A.

10.1101/2024.02.28.581557 — bioinformatics — Posted on 2024-02-29

36 RCE-IFE: Recursive Cluster Elimination with Intra-cluster Feature Elimination

Kuzudisli, C.; Bakir-Gungor, B.; Qaqish, B.; Yousef, M.

10.1101/2024.02.28.580487 — bioinformatics — Posted on 2024-02-29

37 Graph Structured Neural Networks for Perturbation Biology

Evans, N. J.; Mills, G. B.; Wu, G.; Song, X.; McWeeney, S.

10.1101/2024.02.28.582164 — bioinformatics — Posted on 2024-02-29

38 Self-Assembled Protein Vesicles as Vaccine Delivery Platform to Enhance Antigen-Specific Immune Responses

Li, Y.; Champion, J.

10.1101/2024.02.26.582169 — bioengineering — Posted on 2024-02-29

39 Chemical tools to expand the ligandable proteome: diversity-oriented synthesis-based photoreactive stereoprobes

Ogasawara, D.; Konrad, D.; Tan, Z. Y.; Carey, K.; Luo, J.; Won, S. J.; Li, H.; Carter, T.; DeMeester, K.; Njomen, E.; Schreiber, S.; Xavier, R.; Melillo, B.; Cravatt, B.

10.1101/2024.02.27.582206 — biochemistry — Posted on 2024-02-29

40 Genome assembly variation and its implications for gene discovery in nematode species

Mariene, G. M.; Wasmuth, J. D.

10.1101/2024.02.26.582167 — genomics — Posted on 2024-02-29

41 Evidence for the independent evolution of a rectal complex within the beetle superfamily Scarabaeoidea

Beaven, R.; Denholm, B.; Fremlin, M.; Scaccini, D.

10.1101/2024.02.27.582323 — evolutionary biology — Posted on 2024-02-29

42 Illuminating the functional landscape of the dark proteome across the Animal Tree of Life through natural language processing models

Martinez-Redondo, G. I.; Barrios-Nunez, I.; Vazquez-Valls, M.; Rojas, A. M.; Fernandez, R.

10.1101/2024.02.28.582465 — evolutionary biology — Posted on 2024-02-29

43 Dynamics of RNA localization to nuclear speckles are connected to splicing efficiency

Wu, J.; Xiao, Y.; Liu, Y.; Wen, L.; Jin, C.; Liu, S.; Paul, S.; He, C.; Regev, O.; Fei, J.

10.1101/2024.02.29.581881 — cell biology — Posted on 2024-02-29

44 Structural basis of the allosteric regulation of cyanobacterial glucose-6-phosphate dehydrogenase by the redox sensor OpcA

Doello, S.; Shvarev, D.; Theune, M. L.; Sauerwein, J.; Klon, A.; Keskin, E.; Boehm, M.; Gutekunst, K.; Forchhammer, K.

10.1101/2024.02.29.582749 — molecular biology — Posted on 2024-02-29

45 Steroidal glycoalkaloid biosynthesis and fungal tolerance are regulated by ELONGATED HYPOCOTYL 5, SlHY5, in tomato

Sinha, H.; Kumar, R. S.; Datta, T.; Singh, D.; Srivastava, S.; Trivedi, P. K.

10.1101/2024.02.29.582793 — molecular biology — Posted on 2024-02-29

46 Spatio-temporal dynamics of cyanobacterium Dolichospermum lemmermannii populations in a bloom-prone region of Lake Superior

Wood, A.; Callaghan, J. D.; Loiselle, R.; McManus, R. M.; Brovold, S. S.; Wellard Kelly, H. A.; Alexson, E. E.; Sterner, R. W.; Hudson, M. J.; Sheik, C. S.

10.1101/2024.02.28.582538 — microbiology — Posted on 2024-02-29

47 High-Resolution Spatial Transcriptomic Atlas of Mouse Soleus Muscle: Unveiling Single Cell and Subcellular Heterogeneity in Health and Denervation

Hsu, J.-E.; Ruiz, L.; Hwang, Y.; Guzman, S.; Cho, C.-S.; Cheng, W.; Si, Y.; Macpherson, P.; Schrank, M.; Jun, G.; Kang, H.-M.; Kim, M.; Brooks, S.; Lee, J. H.

10.1101/2024.02.26.582103 — physiology — Posted on 2024-02-29

48 Experimental evidence and meta-analysis indicate the negative effect of nosemosis on the survivorship of honeybees

Ostap-Chec, M.; Cait, J.; Scott, W. R.; Arct, A.; Moron, D.; Rapacz, M.; Miler, K.

10.1101/2024.02.27.581909 — pathology — Posted on 2024-02-29

49 Proteomic Characterization of Intrahepatic Cholangiocarcinoma Identifies Distinct Subgroups and Proteins Associated with Time-To-Recurrence

Werner, T.; Budau, K.-L.; Cosenza Contreras, M.; Hause, F.; Kurowski, K.; Pinter, N.; Schueler, J.; Werner, M.; Sigel, C.; Tang, L.; Bronsert, P.; Schilling, O.

10.1101/2024.02.28.582093 — cancer biology — Posted on 2024-02-29

50 Mimicking an in cellulo environment for enzyme-free paper-based nucleic acid tests at the point of care

Beard, J. W.; Hunt, S. L.; Evans, A.; Goenner, C.; Miller, B.

10.1101/2024.02.27.582375 — biophysics — Posted on 2024-02-29

51 Nextflow vs. plain Bash: Different Approaches to the Parallelisation of SNP Calling from the Whole Genome Sequence Data

Sztuka, M.; Kotlarz, K.; Mielczarek, M.; Hajduk, P.; Liu, J.; Szyda, J.

10.1101/2024.02.27.582354 — bioinformatics — Posted on 2024-02-29

52 Virus-derived Synthetic Riboswitches for Real-time Coronaviruses Sensing in Live Cells

Zeng, L.; Qi, L. S.

10.1101/2024.02.27.582433 — bioengineering — Posted on 2024-02-29

53 Genome-wide association study reveals multiple loci for analgesia and heroin taking behavior in outbred rats

Kuhn, B. N.; Cannella, N. N.; Sanchez, T.; Peng, B.; Polesskaya, O.; Gupta, A.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.; Palmer, A. A.

10.1101/2024.02.27.582340 — genetics — Posted on 2024-02-29

54 The Interplay of Ecological Opportunity and Adult Foraging Strategies in Juvenile Sparrow Individual Specialization

Ricote, N.; Weinberger, C.; Ramirez-Otarola, N.; Bustamante, S.; Malaga, M. L.; Barcelo, G.; Sabat, P.; Newsome, S. D.; Maldonado, K.

10.1101/2024.02.29.582146 — ecology — Posted on 2024-02-29

55 Conserved helical motifs in the Ikaros IDR mediate NuRD interaction and transcriptional repression

Zhang, T.; Wang, Y.-F.; Montoya, A.; Nebioglu, N.; Pallikonda, H. A.; Georgieva, R.; Patrascan, I.; King, J. W.; Kramer, H. B.; Shliaha, P. V.; Rueda, D. S.; Merkenschlager, M.

10.1101/2024.02.29.582782 — molecular biology — Posted on 2024-02-29

56 Comprehensive analysis of insertion sequences within rRNA genes of CPR bacteria and biochemical characterization of a homing endonuclease encoded by these sequences

Tsurumaki, M.; Sato, A.; Saito, M.; Kanai, A.

10.1101/2024.02.27.582315 — molecular biology — Posted on 2024-02-29

57 Endometriotic lesions exhibit distinct metabolic signature compared to paired eutopic endometrium at the single-cell level

Sarsenova, M.; Lawarde, A.; Pathare, A.; Saare, M.; Modhukur, V.; Soplepmann, P.; Terasmaa, A.; Kaambre, T.; Gemzell-Danielsson, K.; Lalitkumar, P. G. L.; Salumets, A.; Peters, M.

10.1101/2024.02.27.580606 — molecular biology — Posted on 2024-02-29

58 Mriyaviruses: Small Relatives of Giant Viruses

Yutin, N.; Mutz, P.; Krupovic, M.; Koonin, E. V.

10.1101/2024.02.29.582850 — microbiology — Posted on 2024-02-29

59 Neuronal ARHGAP8 controls synapse structure and AMPA receptor-mediated synaptic transmission

Schmidt, J.; Inacio, A.; Ferreira, J. S.; Serrenho, D.; Socodato, R.; Beltrao, N.; Ribeiro, L. F.; Pinheiro, P.; Relvas, J. B.; Carvalho, A. L.

10.1101/2024.02.29.582472 — neuroscience — Posted on 2024-02-29

60 An Anatomical and Physiological Basis for Coincidence Detection Across Time Scales in the Auditory System

Kreeger, L. J.; Honnuraiah, S.; Maeker, S.; Shea, S.; Fishell, G.; Goodrich, L. V.

10.1101/2024.02.29.582808 — neuroscience — Posted on 2024-02-29

61 Neurophysiological measures of covert semantic processing in neurotypical adolescents actively ignoring spoken sentence inputs: A high-density event-related potential (ERP) study.

Toffolo, K. K.; Freedman, E. G.; Foxe, J. J.

10.1101/2024.02.29.582736 — neuroscience — Posted on 2024-02-29

62 Discovering Genetic Modulators of the Protein Homeostasis System through Multilevel Analysis

Sarsani, V.; Aldikacti, B.; Zhao, T.; He, S.; Chien, P.; Flaherty, P.

10.1101/2024.02.26.582154 — systems biology — Posted on 2024-02-29

63 High-accuracy crRNA array assembly strategy for multiplex CRISPR

Zhao, X.; Yang, L.; Li, P.; Cheng, Z.; Jia, Y.; Luo, L.; Bi, A.; Xiong, H.; Zhang, H.; Zhang, J.; Zhang, Y.

10.1101/2024.02.27.582417 — synthetic biology — Posted on 2024-02-29

64 Effect of translation enhancing nascent SKIK peptide on the arrest peptides containing consecutive Proline

Nishikawa, Y.; Fujikawa, R.; Nakano, H.; Ojima-Kato, T.

10.1101/2024.02.28.582505 — synthetic biology — Posted on 2024-02-29

65 Designing a hybrid in silico/in-cell controller robust to process-model mismatch associated with dynamically regulated enzyme overexpression

Ohkubo, T.; Sakumura, Y.; Zhang, F.; Kunida, K.

10.1101/2024.02.27.582404 — synthetic biology — Posted on 2024-02-29

66 Statistical design of a synthetic microbiome that clears a multi-drug resistant gut pathogen

Oliveira, R.; Pandey, B.; Lee, K.; Yousef, M.; Chen, R. Y.; Triebold, C.; McSpadden, E.; Haro, F.; Aksianiuk, V.; Ramanujam, R.; Kuehn, S.; Raman, A.

10.1101/2024.02.28.582635 — synthetic biology — Posted on 2024-02-29

67 Genome-Wide Association Study Reveals Influence of Cell-specific Gene Networks on Soybean Root System Architecture

Sun, Y.; Miler, C.; Rajurkar, A.; Lynch, R.; Aylward, A.; Zhang, L.; Shaner, M.; Copeland, C.; Ye, H.; Nguyen, H. T.; Busch, W.; Michael, T. P.

10.1101/2024.02.27.581071 — plant biology — Posted on 2024-02-29

68 PTM-Mamba: A PTM-Aware Protein Language Model with Bidirectional Gated Mamba Blocks

Peng, Z.; Schussheim, B.; Chatterjee, P.

10.1101/2024.02.28.581983 — bioinformatics — Posted on 2024-02-29

69 doubletrouble: an R/Bioconductor package for the identification, classification, and analysis of gene and genome duplications

Almeida-Silva, F.; Van de Peer, Y.

10.1101/2024.02.27.582236 — bioinformatics — Posted on 2024-02-29

70 Detecting Genetic Interactions with Visible Neural Networks

van Hilten, A.; Melograna, F.; Fan, B.; Niessen, W. J.; van Steen, K.; Roshchupkin, G. V.

10.1101/2024.02.27.582086 — bioinformatics — Posted on 2024-02-29

71 Exploring Genomic Large Language Models: Bridging the Gap between Natural Language and Gene Sequences

Liu, H.; Zhou, S.; Chen, P.; Liu, J.; Huo, K.-G.; Han, L.

10.1101/2024.02.26.581496 — bioinformatics — Posted on 2024-02-29

72 Three-dimensional flow assessment of microvascular beds with interstitial space

Rajeeva Pandian, N. K.; Farell, A. M.; Davis, E. E.; Sundaram, S.; Teo, J. L. C.; Eyckmans, J.; Chen, C. S.

10.1101/2024.02.28.582152 — bioengineering — Posted on 2024-02-29

73 Intracellular biomacromolecule delivery by stimuli responsive protein vesicles loaded by hydrophobic ion pairing

Gray, M. A.; de Janon, A.; Seeler, M.; Heller, W. T.; Panoskaltsis, N.; Mantalaris, A.; Champion, J. A.

10.1101/2024.02.27.582187 — bioengineering — Posted on 2024-02-29

74 Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions.

Almeida, T.; Hargreaves, E.; Zech, T. N.; Barsukov, I.

10.1101/2024.02.27.581919 — biochemistry — Posted on 2024-02-29

75 Targeting Tuberculosis: Novel Scaffolds for Inhibiting Cytochrome bd Oxidase

Seitz, C.; Ahn, S.-H.; Wei, H.; Kyte, M.; Cook, G.; Krausd, K.; McCammon, J. A.

10.1101/2024.02.28.582612 — biochemistry — Posted on 2024-02-29

76 Codon Pair-Specific Translation Defects Trigger Ribosome-Associated Quality Control to Avoid Proteotoxic Stress

Wu, J.; Eggers, C.; Sin, O.; Koziej, L.; Mancilla, H.; Mollet, F.; Scholer, H. R.; Drexler, H. C.; Ranff, T.; Fufezan, C.; Kraft, C.; Glatt, S.; Bruder, J. M.; Leidel, S. A.

10.1101/2024.02.27.582385 — biochemistry — Posted on 2024-02-29

77 Pouch microbiome changes during lactation in the short-beaked echidna (Tachyglossus aculeatus)

Wilson, I.; Perry, T.; Eisenhofer, R.; Rismiller, P.; Shaw, M.; Grutzner, F.

10.1101/2024.02.28.581309 — genomics — Posted on 2024-02-29

78 Digesting the data: Proper validation in ancient metagenomic studies is essential

Pach, A. L.; Lanigan, L. T.; Schroeder, H.; Pedersen, M. W.; Niemann, J.

10.1101/2024.02.27.581519 — genomics — Posted on 2024-02-29

79 Whole genome sequencing of four Ixodes species expands understanding of tick evolution

Cerqueira de Araujo, A.; Noel, B.; Bretaudeau, A.; Labadie, K.; Boudet, M.; Tadrent, N.; Istace, B.; Kritli, S.; Cruaud, C.; Olaso, R.; Deleuze, J.-F.; Voordouw, M.; Hervet, C.; Plantard, O.; Zamoto-Niikura, A.; Chertemps, T.; Maibeche, M.; Hilliou, F.; Le Goff, G.; Kopacek, P.; Perner, J.; Chmelar, J.; Mazak, V.; Jmel, M. A.; Kotsyfakis, M.; Medina, J. M.; Hackenberg, M.; Simo, L.; Wincker, P.; Aury, J.-M.; Rispe, C.

10.1101/2024.02.29.581698 — genomics — Posted on 2024-02-29

80 A temporal sequence of heterochronic gene activities promotes stage-specific developmental events in C. elegans

Ivanova, M.; Moss, E. G.

10.1101/2024.02.26.582127 — genetics — Posted on 2024-02-29

81 A SNP-based honey bee paternity assignment test for evaluating the effectiveness of mating stations and its application to the Ataun valley, Basque Country, Spain

Parejo, M.; Galartza, E.; Momeni, J.; Gorrochategui-Ortega, J.; Farajzadeh, L.; Wegener, J.; Bienefeld, K.; Zarraonaindia, I.; Estonba, A.

10.1101/2024.02.27.580467 — genetics — Posted on 2024-02-29

82 Biogenesis of circular RNAs in vitro and in vivo from the Drosophila Nk2.1/scarecrow gene

Son, S.; Jeong, H.; Lee, G. G.; Park, J. H.; Yoo, S.

10.1101/2024.02.26.582126 — genetics — Posted on 2024-02-29

83 Separation of telomere protection from length regulation by two different point mutations at amino acid 492 of RTEL1

Smoom, R.; May, C. L.; Skordalakes, E.; Kaestner, K. H.; Tzfati, Y.

10.1101/2024.02.26.582005 — genetics — Posted on 2024-02-29

84 Functional overlap between the mammalian SAR1A and SAR1B paralogs in vivo

Tang, V. T.; Xiang, J.; Chen, Z.; McCormick, J.; Abbineni, P.; Chen, X.-W.; Hoenerhoff, M.; Emmer, B. T.; Khoriaty, R.; Lin, J. D.; Ginsburg, D.

10.1101/2024.02.27.582310 — genetics — Posted on 2024-02-29

85 Taste evolution in an herbivorous drosophilid

Pelaez, J. N.; Bernstein, S. N.; Okoro, J.; Rodas, E.; Liang, I.; Leipertz, A.; Marion-Poll, F.; Whiteman, N. K.

10.1101/2024.02.27.582299 — evolutionary biology — Posted on 2024-02-29

86 Nicotinamide riboside activates renal metabolism and protects the kidney in a model of Alport syndrome

Jones, B. A.; Gisch, D. L.; Myakala, K.; Sadiq, A.; Cheng, Y.-H.; Taranenko, E.; Panov, J.; Korolowicz, K.; Wang, X.; Rosenberg, A. Z.; Jain, S.; Eadon, M. T.; Levi, M.

10.1101/2024.02.26.580911 — molecular biology — Posted on 2024-02-29

87 Enzymatic Assembly for CRISPR Split-Cas9 System: The Emergence of a Sortase-based Split-Cas9 Technology

Sun, Y.; Helalat, S. H.; Tellez, R. C.

10.1101/2024.02.29.582732 — molecular biology — Posted on 2024-02-29

88 A novel LysinB from an F2 sub-cluster mycobacteriophage RitSun

Arora, R.; Nadar, K.; Bajpai, U.

10.1101/2024.02.29.582697 — molecular biology — Posted on 2024-02-29

89 Subcellular thermal profiling enables the deep functional exploration of the mitochondrial proteome

Rivera-Mejias, P.; Le Sueur, C.; Kurzawa, N.; Becher, I.; Savitski, M. M.

10.1101/2024.02.27.582308 — molecular biology — Posted on 2024-02-29

90 Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo

Tsugawa, Y.; Furukawa, K.; Ise, T.; Takayama, M.; Ota, T.; Kuroda, T.; Shano, S.; Hashimoto, T.; Konishi, H.; Ishihara, T.; Sato, M.; Kamada, H.; Fukao, K.; Shishido, T.; Takahashi, T.; Nagata, S.

10.1101/2024.02.28.582480 — microbiology — Posted on 2024-02-29

91 Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase

Schmerling, C.; Schroeder, C.; Zhou, X.; Busche, T.; Kalinowski, J.; Montero, L.; Schmitz, O.; Kaschani, F.; Ninck, S.; Kaiser, M.; Bost, J.; Recalde, A.; Albers, S.-V.; Siebers, B.; Braesen, C.

10.1101/2024.02.29.582781 — microbiology — Posted on 2024-02-29

92 Timescales and genetic linkage explain the variable impact of defense systems on horizontal gene transfer

Liu, Y.; Botelho, J.; Iranzo, J.

10.1101/2024.02.29.582795 — microbiology — Posted on 2024-02-29

93 Distinct Escherichia coli transcriptional profiles in the guts of recurrent UTI sufferers revealed by pan-genome hybrid selection

Young, M. G.; Straub, T. J.; Worby, C. J.; Metsky, H. C.; Gnirke, A.; Bronson, R. A.; van Dijk, L. R.; Desjardins, C. A.; Matranga, C.; Qu, J.; Dodson, K.; Schreiber, H. L.; Manson, A. L.; Hultgren, S. J.; Earl, A. M.

10.1101/2024.02.29.582780 — microbiology — Posted on 2024-02-29

94 ORF48 is required for optimal lytic replication of Kaposis Sarcoma-Associated Herpesvirus

Veronese, B. H. S.; Nguyen, A.; Patel, K.; Paulsen, K.; Ma, Z.

10.1101/2024.02.29.582672 — microbiology — Posted on 2024-02-29

95 Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

Clark, J.; Hoxie, I.; Adelsberg, D.; Sapse, I.; Andreata-Santos, R.; Yong, J.; Amanat, F.; Tcheou, J.; Raskin, A.; Singh, G.; Gonzalez-Dominguez, I.; Edgar, J.; Bournazos, S.; Sun, W.; Carreno, J. M.; Simon, V.; Ellebedy, A.; Krammer, F.

10.1101/2024.02.28.582613 — immunology — Posted on 2024-02-29

96 Treponema pallidum periplasmic and membrane proteins are recognized by circulating and skin CD4+ T cells

Reid, T. B.; Godornes, C.; Campbell, V. L.; Laing, K. J.; Tantalo, L. C.; Gomez, A.; Pholsena, T. N.; Lieberman, N. A. P.; Krause, T. M.; Cegielski, V. I.; Culver, L. A.; Nguyen, N.; Tong, D. Q.; Hawley, K. L.; Greninger, A. L.; Giacani, L.; Cameron, C. E.; Dombrowski, J. C.; Wald, A.; Koelle, D. M.

10.1101/2024.02.27.581790 — immunology — Posted on 2024-02-29

97 Multi-COBRA hemagglutinin formulated with cGAMP microparticles elicit protective immune responses against influenza viruses

Zhang, X.; Shi, H.; Hendry, D.; Bachelder, E. M.; Ainslie, K. M.; Ross, T.

10.1101/2024.02.27.582355 — immunology — Posted on 2024-02-29

98 Awareness is determined by emotion and gender

Jugovic, E.; Poyo Solanas, M.; de Gelder, B.

10.1101/2024.02.27.579317 — neuroscience — Posted on 2024-02-29

99 A general strategy to engineer high-performance mammalian Whole-Cell Biosensors

di Bernardo, D.; Mallozzi, A.; Fusco, V.; Ragazzini, F.; Praznik, A.; Jerala, R.

10.1101/2024.02.28.582526 — synthetic biology — Posted on 2024-02-29

100 Spatial heterogeneity in collective electrotaxis: continuum modelling and applications to optimal control

Martina-Perez, S. F.; Breinyn, I. B.; Cohen, D. J.; Baker, R. E.

10.1101/2024.02.28.580259 — biophysics — Posted on 2024-02-29

101 Peptide Mold: A Novel Strategy for Mapping Potential Binding Sites in Protein Targets

Bagwe, P. B.; Jagtap, Y.; Ghegade, V.; Machhar, J. S.; Martis, E.; Joshi, S. V.; Kharkar, P. S.

10.1101/2024.02.28.582665 — bioinformatics — Posted on 2024-02-29

102 SIRT2-Mediated ACSS2 K271 Deacetylation Suppresses Lipogenesis Under Nutrient Stress

Karim, R.; Teng, W.; Lin, H.

10.1101/2024.02.27.582293 — biochemistry — Posted on 2024-02-29

103 Hachiman is a genome integrity sensor

Tuck, O. T.; Adler, B. A.; Armbruster, E. G.; Lahiri, A.; Hu, J. J.; Zhou, J.; Pogliano, J.; Doudna, J. A.

10.1101/2024.02.29.582594 — biochemistry — Posted on 2024-02-29

104 Long-term survival of asexual Zymoseptoria tritici spores in the environment

Kay, W. T.; O'Neill, P.; Gurr, S. J.; Fones, H. N.

10.1101/2024.02.29.582720 — microbiology — Posted on 2024-02-29

105 Continuously fluctuating selection reveals extreme granularity and parallelism of adaptive tracking

Bitter, M. C.; Berardi, S.; Oken, H.; Huynh, A.; Schmidt, P.; Petrov, D. A.

10.1101/2023.10.16.562586 — evolutionary biology — Posted on 2024-02-29

106 Characterisation of prophages in Clostridium clostridioforme: an understudied component of the intestinal microbiome

Humphrey, S.; Marouli, A.; Thummler, K.; Mullin, M.; Wall, D. M.

10.1101/2024.02.29.582698 — microbiology — Posted on 2024-02-29

107 Both environmental conditions and intra- and interspecific interactions influence the movements of a marine predator

Mourier, J.; Soria, M.; Silk, M.; Demichelis, A.; Dagorn, L.; Hattab, T.

10.1101/2024.02.26.582077 — ecology — Posted on 2024-02-29

108 The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the gut

Zhang, Y.; Li, Y.; Noya, S. B.; Sehgal, A.

10.1101/2024.02.29.582770 — microbiology — Posted on 2024-02-29

109 Curcumin and turmeric extract inhibit SARS-CoV-2 pseudovirus cell entry and Spike mediated cell fusion

Septisetyani, E. P. P.; Lestari, D.; Paramitasari, K. A.; Prasetyaningrum, P. W.; Kastian, R. F.; Anam, K.; Santoso, A.; Eriani, K.

10.1101/2023.09.28.560070 — pharmacology and toxicology — Posted on 2024-02-29

110 Bayesian Hierarchical Hypothesis Testing in Large-Scale Genome-Wide Association Analysis

Samaddar, A.; Maiti, T.; de los Campos, G.

10.1101/2024.02.26.582204 — genetics — Posted on 2024-02-29

111 Adaptation strategies of iron-oxidizing bacteria Gallionella and Zetaproteobacteria crossing the marine-freshwater barrier

Hribovsek, P.; Olesin Denny, E.; Mall, A.; Dahle, H.; Steen, I. H.; Stokke, R.

10.1101/2024.02.28.582575 — microbiology — Posted on 2024-02-29

112 Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure

Ence, C. C.; Uddin, T.; Borrel, J.; Mittal, P.; Xie, H.; Zoller, J.; Sharma, A.; Comer, E.; Schreiber, S. L.; Melillo, B.; Sibley, L. D.; Chatterjee, A. K.

10.1101/2024.02.28.582607 — microbiology — Posted on 2024-02-29

113 The predicted secreted proteome of activated sludge microorganisms indicate distinct nutrient niches

Wasmund, K.; Singleton, C.; Dueholm, M. S.; Wagner, M.; Nielsen, P. H.

10.1101/2024.02.27.582363 — microbiology — Posted on 2024-02-29

114 Constitutive upregulation of transcription factors underlies permissive bradyzoite differentiation in a natural isolate of Toxoplasma gondii.

Xia, J.; Fu, Y.; Huang, W.; Sibley, L. D.

10.1101/2024.02.28.582596 — microbiology — Posted on 2024-02-29

115 Syngap1 regulates the synaptic drive and membrane excitability of Parvalbumin-positive interneurons in mouse auditory cortex

Francavilla, R.; Chattopadhyaya, B.; Damo Kamda, J. L.; Jadhav, V.; Kourrich, S.; Michaud, J. L.; Di Cristo, G.

10.1101/2024.02.27.582362 — neuroscience — Posted on 2024-02-29

116 Blood metabolomic profiling reveals new targets in the management of psychological symptoms associated with alcohol use disorder

Leclercq, S.; Ahmed, H.; Amadieu, C.; Petit, G.; Koistinen, V.; Leyrolle, Q.; Poncin, M.; Stärkel, P.; Kok, E.; Karhunen, P. J.; de Timary, P.; Laye, S.; Neyrinck, A. M.; Kärkkäinen, O. K.; Hanhineva, K.; Delzenne, N.

10.1101/2024.02.27.582239 — neuroscience — Posted on 2024-02-29

117 WITHDRAWN: The adhesion GPCR Adgrd1 is a prion protein receptor and a mediator of prion cytotoxicity

Lakkaraju, A. K.; Tejero, O.; Guixa-Gonzalez, R.; De Cecco, E.; Jungo, M.; Tsai, C.-J.; Mastromartino, R.; Marino, J.; Deupi, X.; Hornemann, S.; Schertler, G. F. X.; Aguzzi, A.

10.1101/2023.04.29.538801 — neuroscience — Posted on 2024-02-29

118 Single Testicular Biopsy: Changes in the vascular architecture of the tunica albuginea

Oliveira Filho, A. B. d.; Peruquetti, R.; Rasmussen, L. T.; Cesar, M. T.; Centola, C. A. P.; Cedenho, A. P.

10.1101/2024.02.26.582049 — pathology — Posted on 2024-02-29

119 Pharmacodynamic evaluation of AUM001/tinodasertib, an oral inhibitor of mitogen-activated protein kinase (MAPK)-interacting protein kinase 1, 2 (MNK1/2) in preclinical models and tissues from a Phase 1 clinical study

Gan, B. H.; Lee, L. H.; Takeda, R.; Yasin, M.; Teneggi, V.; Ethirajulu, K.; Yeo, P.; Umrani, D.; Pendharkar, V.; Lim, D. W. T.; Li, G.; Lu, Q.; Cao, Y.; Nellore, R.; Blanchard, S.; HENTZE, H.; Novotny-Diermayr, V.

10.1101/2024.02.23.581717 — cancer biology — Posted on 2024-02-29

120 A Lung Cancer Mouse Model Database

Cai, L.; Gao, Y.; DeBerardinis, R. J.; Chen, T.; Winslow, M. M.; Xiao, G.; Rudin, C.; Oliver, T. G.; Minna, J. D.; Xie, Y.

10.1101/2024.02.28.582577 — cancer biology — Posted on 2024-02-29

121 Sci-comm "behind the scenes": Gendered narratives of scientific outreach activities in the life sciences

Beasley-Hall, P. G.; Papadelos, P.; Hewitt, A.; Umbers, K. D. L.; Guzik, M. T.

10.1101/2024.02.28.582614 — scientific communication and education — Posted on 2024-02-29

122 Accelerating Single-Cell Sequencing Data Analysis with SciDAP: A User-Friendly Approach

Kotliar, M.; Kartashov, A.; Barski, A.

10.1101/2024.02.28.582604 — bioinformatics — Posted on 2024-02-29

123 Diplopoda in the world fossil record

Alvarez Rodriguez, M.; Riquelme, F.; Patricio, M. A. H.; Cupul-Magana, F.

10.1101/2024.02.21.581465 — paleontology — Posted on 2024-02-29

124 Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control

Detres Roman, C. R.; Rudloff, M. W.; Revetta, F.; Favret, N. R.; Murray, K. A.; Roetman, J. J.; Erwin, M. M.; Washington, M. K.; Philip, M.

10.1101/2024.02.26.582064 — cancer biology — Posted on 2024-02-29

125 Caspase-resistant ROCK1 expression prolongs survival of E-mu-Myc B cell lymphoma mice.

Mardilovich, K.; Naylor, G.; Julian, L.; Phinichkusolchit, N.; Keeshan, K.; Blyth, K.; Olson, M. F.

10.1101/2024.02.26.582074 — cancer biology — Posted on 2024-02-29

126 Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution

Peters, A. L.; DePasquale, E. A.; Begum, G.; Roskin, K. M.; Woodle, E. S.; Hildeman, D. A.

10.1101/2024.02.26.582173 — immunology — Posted on 2024-02-29

127 Stiffness Measurement of Retinal Capillaries and Subendothelial Matrix using Atomic Force Microscopy

Santiago Tierno, I.; Agarwal, M.; Matisioudis, N.; Chandrakumar, S.; Ghosh, K.

10.1101/2024.02.28.582372 — pathology — Posted on 2024-02-29

128 Detecting Somatic Mutations Without Matched Normal Samples Using Long Reads

Simpson, J. T.

10.1101/2024.02.26.582089 — bioinformatics — Posted on 2024-02-29

129 On Monitoring Brain Health from the Depths of Sleep: Feature Engineering and Machine Learning Insights for Digital Biomarker Development

McConnell, B. V.; Liu, Y.; Biswas, A. K.; Bettcher, B. M.; Medenblik, L. M.; Broussard, J. L.; Lucey, B. P.; Ramos, A. R.; Kheyfets, V. O.

10.1101/2024.02.27.581950 — neuroscience — Posted on 2024-02-29

130 A mediating framework in resting-state connectivity between the medial prefrontal cortex and anterior cingulate in mild cognitive impairment

Huang, Y. T.; Yan, S.-H.; Chuang, Y.-F.; Shih, Y.-C.; Huang, Y.-S.; Liu, Y.-C.; Kao, S. S.-C.; Chiu, Y.-L.; Fan, Y.-T.

10.1101/2024.02.27.582424 — neuroscience — Posted on 2024-02-29

131 Electrophysiological approaches to understanding brain-muscle interactions during gait: a systematic review

Seynaeve, M.; Mantini, D.; de Beukelaar, T. T.

10.1101/2024.02.27.582247 — neuroscience — Posted on 2024-02-29

132 Distinctive retinal peri-arteriolar versus peri-venular amyloid plaque distribution correlates with the cognitive performance

Dumitrascu, O. M.; Doustar, J.; Fuchs, D.-T.; Koronyo, Y.; Sherman, D. S.; Miller, M. S.; Johnson, K. O.; Carare, R. O.; Verdooner, S. R.; Lyden, P. D.; Schneider, J. A.; Black, K. L.; Koronyo-Hamaoui, M.

10.1101/2024.02.27.580733 — pathology — Posted on 2024-02-29

133 mRNA-delivered consensus allergens induce a neutralizing IgG response against food and pollen allergens

Moiniche, M.; Johansen, K. H.; Parron-Ballesteros, J.; Corneliussen, J. K.; Eriksen, H. H.; Kringelum, J. V.; Hadrup, S. R.; Luengo, O.; Cardona, V.; Bartra, J.; Pascal, M.; Turnay, J.; Villalba, M.; Munter, R.; Jenkins, T. P.; Laustsen, A. H.; Rivera-de-Torre, E.

10.1101/2024.02.26.582073 — bioengineering — Posted on 2024-02-29

134 Enlighting the toxinological dark matter of spider venom enzymes

Dresler, J.; Herzig, V.; Vilcinskas, A.; Lueddecke, T.

10.1101/2024.02.27.582330 — biochemistry — Posted on 2024-02-29

135 Meta-analysis of the human gut microbiome uncovers shared and distinct microbial signatures between diseases

Jin, D.-M.; Morton, J.; Bonneau, R.

10.1101/2024.02.27.582333 — microbiology — Posted on 2024-02-29

136 ADAMTS7 Promotes Smooth Muscle Cell Foam Cell Expansion in Atherosclerosis

Chung, A.; Chang, H. K.; Pan, H.; Bashore, A. C.; Shuck, K.; Matias, C. V.; Gomez, J.; Yan, H.; Li, M.; Bauer, R. C.

10.1101/2024.02.26.582156 — pathology — Posted on 2024-02-29

137 Discovery of the First-in-class G9a/GLP PROTAC Degrader

Velez, J.; Han, Y.; Yim, H.; Yang, P.; Deng, Z.; Park, K.; Kabir, M.; Kaniskan, H.; Xiong, Y.; Jin, J.

10.1101/2024.02.26.582210 — biochemistry — Posted on 2024-02-29

138 Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD

Rezaie, N.; Rebboah, E.; Williams, B. A.; Liang, H. Y.; Reese, F.; Balderrama-Gutierrez, G.; Dionne, L.; Reinholdt, L. G.; Trout, D.; Wold, B.; Mortazavi, A.

10.1101/2024.02.26.582178 — genomics — Posted on 2024-02-29

139 Glyphosate resistance evolution to lethal and sublethal doses in chemostat populations of model organism Chlamydomonas reinhardtii

Hansson, E. M.; Childs, D. Z.; Beckerman, A. P.

10.1101/2024.02.26.582134 — evolutionary biology — Posted on 2024-02-29

140 Causal inference with observational data and unobserved confounding variables

Byrnes, J. E. K.; Dee, L. E.

10.1101/2024.02.26.582072 — ecology — Posted on 2024-02-29

141 Evidence for a trade-off between glyphosate resistance and anti-grazer defence in green alga Chlamydomonas reinhardtii

Hansson, E. M.; Childs, D. Z.; Beckerman, A. P.

10.1101/2024.02.26.582141 — ecology — Posted on 2024-02-29

142 Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

Makela, J.; Papagiannakis, A.; Lin, W.-H.; Lanz, M. C.; Glenn, S.; Swaffer, M.; Marinov, G. K.; Skotheim, J. M.; Jacobs-Wagner, C.

10.1101/2024.02.26.582181 — cell biology — Posted on 2024-02-29

143 The Bacterial Quorum-Sensing Signal 2-Aminoacetophenone Rewires Immune Cell Bioenergetics through the PGC-1α/ERRα Axis to Mediate Tolerance to Infection

Chakraborty, A.; Bandyopadhaya, A.; SINGH, V.; Kovacic, F.; Cha, S.; Oldham, W.; Tzika, A. A.; Rahme, L.

10.1101/2024.02.26.582124 — immunology — Posted on 2024-02-29

144 Metaplastic neuromodulation via transcranial direct current stimulation has no effect on corticospinal excitability and neuromuscular fatigue

Boda, M. R.; Otieno, L. A.; Smith, A. E.; Goldsworthy, M. R.; Sidhu, S. K.

10.1101/2024.02.25.581971 — neuroscience — Posted on 2024-02-29

145 CONVERGENCE, SAMPLING AND TOTAL ORDER ESTIMATOR EFFECTS ON PARAMETER ORTHOGONALITY IN GLOBAL SENSITIVITY ANALYSIS

Saxton, H.; Xu, X.; Schenkel, T.; Clayton, R. H.; Halliday, I.

10.1101/2024.02.25.582013 — systems biology — Posted on 2024-02-29

146 scConfluence : single-cell diagonal integration with regularized Inverse Optimal Transport on weakly connected features

Samaran, J.; Peyre, G.; Cantini, L.

10.1101/2024.02.26.582051 — bioinformatics — Posted on 2024-02-29

147 Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

Hai, H. T.; Nhat, L. T. H.; Tram, T. T. B.; Vinh, D. D.; Nath, A. P.; Donovan, J.; Thu, N. T. A.; Thanh, D. V.; Bang, N. D.; Ha, D. T. M.; Phu, N. H.; Nghia, H. D. T.; Van, L. H.; Inouye, M.; Thwaites, G. E.; Thuong, N. T. T.

10.1101/2023.10.06.561265 — molecular biology — Posted on 2024-02-29

148 Bacteria use spatial sensing to direct chemotaxis on surfaces

Wheeler, J. H. R.; Foster, K. R.; Durham, W. M.

10.1101/2024.02.13.580113 — microbiology — Posted on 2024-02-29

149 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.

Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.

10.1101/2023.12.12.571374 — neuroscience — Posted on 2024-02-29

150 Curriculum learning inspired by behavioral shaping trains neural networks to adopt animal-like decision making strategies

Hocker, D. L.; Constantinople, C. M.; Savin, C.

10.1101/2024.01.12.575461 — neuroscience — Posted on 2024-02-29

151 Using a Förster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain

Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.

10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-02-29

152 BRAKER3: Fully Automated Genome Annotation Using RNA-Seq and Protein Evidence with GeneMark-ETP, AUGUSTUS and TSEBRA

Gabriel, L.; Bruna, T.; Hoff, K. J.; Ebel, M.; Lomsadze, A.; Borodovsky, M.; Stanke, M.

10.1101/2023.06.10.544449 — bioinformatics — Posted on 2024-02-29

153 Rapid in situ mutation detection in extracellular vesicle-DNA

Rahman, M. M.; Wang, L.; Rahman, M. M.; Chen, Y.; Zhang, W.; Wang, J.; Lee, L.; Wan, Y.

10.1101/2024.02.26.582068 — bioengineering — Posted on 2024-02-29

154 A ubiquitin-specific, proximity-based labeling approach for the identification of ubiquitin ligase substrates

Mukhopadhyay, U.; Levantovsky, S.; Gharbi, S.; Stein, F.; Behrends, C.; Bhogaraju, S.

10.1101/2023.09.04.556194 — biochemistry — Posted on 2024-02-29

155 Experimental evolution in maize with replicated divergent selection identifies plant-height associated SNPs

Tost, M.; Westhues, C.; Morrison, G.; Dietrich, K.; Beissinger, T.

10.1101/2024.02.26.582128 — genetics — Posted on 2024-02-29

156 Rapid evolution of genes with anti-cancer functions during the origins of large bodies and cancer resistance in elephants

Bowman, J.; Lynch, V. J.

10.1101/2024.02.27.582135 — evolutionary biology — Posted on 2024-02-29

157 Phylogenetic signal in primate tooth enamel proteins and its relevance for paleoproteomics

Krueger, J.; Fong Zazueta, R.; Alba, D. M.; Aymerich, X.; Beck, R. M. D.; Cappellini, E.; Carrillo Martin, G.; Cirilli, O.; Clark, N.; Cornejo, O. E.; Farh, K.; Ferrandez-Peral, L.; Juan, D.; Kelley, J. L.; Kuderna, L. F. K.; Little, J.; Orkin, J. D.; Paterson, R. S.; Pawar, H.; Marques-Bonet, T.; Lizano, E.

10.1101/2024.02.28.580462 — evolutionary biology — Posted on 2024-02-29

158 Cephalopod Sex Determination and its Ancient Evolutionary Origin Revealed by Chromosome-level Assembly of the California two-spot Octopus

Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.

10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-02-29

159 Ontogenetic variation in the marine foraging of Atlantic salmon functionally links genomic diversity with a major life history polymorphism

Aykanat, T.; Jacobsen, J. A.; Hindar, K.

10.1101/2024.02.26.581711 — ecology — Posted on 2024-02-29

160 DVL1 variants and C-terminal deletions have differential effects on craniofacial development and WNT signaling

Tophkhane, S. S.; Gignac, S. J.; Verheyen, E. M.; Richman, J.

10.1101/2024.02.28.582602 — developmental biology — Posted on 2024-02-29

161 Craniofacial studies in chicken embryos confirm the pathogenicity of Frizzled2 variants associated with Robinow syndrome

Tophkhane, S. S.; Fu, K.; Verheyen, E. M.; Richman, J. M.

10.1101/2023.11.07.565956 — developmental biology — Posted on 2024-02-29

162 Coordination between cytoskeletal organization, cell contraction and extracellular matrix development, is depended on LOX for aneurysm prevention

Aviram, R.; Zaffryar-Eilot, S.; Kaganovsky, A.; Odeh, A.; Melamed, S.; Militsin, R.; Pinnock, C. B.; Shemesh, A.; Palty, R.; Ganesh, S. K.; Hasson, P.

10.1101/2024.02.23.581837 — cell biology — Posted on 2024-02-29

163 CEP44 is required for maintaining centriole duplication and spindle integrity

Zhang, D.; Wei, W.; Zou, X.; Meng, H.; Li, F.; Yao, M.; Teng, J.; Huang, N.; Chen, J.

10.1101/2023.11.20.567852 — cell biology — Posted on 2024-02-29

164 Proteomic and lipidomic alterations of high-density lipoprotein: Perimenopause is characterized by small triacylglycerols-enriched particles.

Lehti, S.; Korhonen, T.-M.; Soliymani, R.; Ruhanen, H.; Lahteenmaki, E.; Palviainen, M.; Siljander, P.; Lalowski, M.; Kakela, R.; Lehti, M.; Laakkonen, E. K.

10.1101/2024.01.10.574516 — molecular biology — Posted on 2024-02-29

165 A ventral hippocampal-lateral septum pathway regulates social novelty preference.

Rashid, M.; Thomas, S.; Isaac, J.; Karkare, S.; Klein, H.; Murugan, M.

10.1101/2024.02.28.582638 — neuroscience — Posted on 2024-02-29

166 A growth chart of brain function from infancy to adolescence based on electroencephalography

Iyer, K. K.; Roberts, J. A.; Waak, M.; Vogrin, S. J.; Kevat, A.; Chawla, J.; Haataja, L. M.; Lauronen, L.; Vanhatalo, S.; Stevenson, N. J.

10.1101/2023.07.07.548062 — neuroscience — Posted on 2024-02-29

167 High quality genome assembly of the brown hare (Lepus europaeus) with chromosome-level scaffolding

Michell, C.; Collins, J.; Laine, P. K.; Fekete, Z.; Tapanainen, R.; Wood, J. M. D.; Goffart, S.; Pohjoismaki, J. L. O.

10.1101/2023.08.29.555262 — genomics — Posted on 2024-02-28

168 The genome of Przewalski's horse (Equus ferus przewalskii)

Flack, N.; Hughes, L.; Cassens, J.; Enriquez, M.; Gebeyehu, S.; Alshagawi, M.; Hatfield, J.; Kauffman, A.; Brown, B.; Klaeui, C.; Malbrouk, I. F.; Walls, C.; Yeater, T.; Rivas, A.; Faulk, C.

10.1101/2024.02.20.581252 — genomics — Posted on 2024-02-28

169 Near telomere-to-telomere genome assemblies of two Chlorella species unveil the composition and evolution of centromeres in green algae

Wang, B.; Jia, Y.; Dang, N.; Yu, J.; Bush, S. J.; Gao, S.; He, W.; Wang, S.; Guo, H.; Yang, X.; Ma, W.; Ye, K.

10.1101/2024.02.27.582245 — genomics — Posted on 2024-02-29

170 Effective population size does not explain long-term variation in genome size and transposable element content in animals

Marino, A.; Debaecker, G.; Fiston-Lavier, A.-S.; Haudry, A.; Nabholz, B.

10.1101/2024.02.26.582137 — evolutionary biology — Posted on 2024-02-29

171 The binding of Mint/X11 PDZ domains to CaV2 calcium channels predates bilaterian animals

Harracksingh, A. N.; Singh, A.; Mayorova, T.; Bejoy, B.; Hornbeck, J.; Elkhatib, W.; McEdwards, G.; Gauberg, J.; Taha, A. R. W.; Islam, I. M.; Erclik, T.; Currie, M. A.; Noyes, M.; Senatore, A.

10.1101/2024.02.26.582151 — evolutionary biology — Posted on 2024-02-29

172 One Hundred Years of Influenza A Evolution

Nielsen, B. F.; Berrig, C.; Grenfell, B. T.; Andreasen, V.

10.1101/2024.02.27.582392 — evolutionary biology — Posted on 2024-02-29

173 Neurogenesis and neuronal migration in hypothalamic vasopressinergic magnocellular nuclei of the adult rat

Zhang, L.; Zetter, M. A.; Hernandez, V. S.; Brabichler, Q.; Grinevich, V.

10.1101/2023.12.10.570983 — neuroscience — Posted on 2024-02-28

174 Evaluating batch correction methods for image-based cell profiling

Arevalo, J.; Su, E.; van Dijk, R.; Carpenter, A. E.; Singh, S.

10.1101/2023.09.15.558001 — bioinformatics — Posted on 2024-02-28

175 In defense of Apocynaceae: inference on evolution of pyrrolizidine alkaloids from evolution of an enzyme in their biosynthetic pathway, homospermidine synthase

Smith, C. R.; Kaltenegger, E.; Teisher, J.; Moore, A. J.; Straub, S. C. K.; Livshultz, T.

10.1101/2023.04.01.535177 — evolutionary biology — Posted on 2024-02-28

176 Lens Placode Modulates Extracellular Matrix Formation During Early Eye Development

de Magalhaes, C. G.; Cvekl, A.; Jaeger, R. G.; Yan, C. Y. I.

10.1101/2023.11.30.569417 — developmental biology — Posted on 2024-02-28

177 Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET derived features

Dörfel, R. P.; Arenas-Gomez, J. M.; Svarer, C.; Ganz, M.; Knudsen, G. M.; Svensson, J.; Plaven-Sigray, P.

10.1101/2024.02.05.578968 — neuroscience — Posted on 2024-02-28

178 Selective consolidation of learning and memory via recall-gated plasticity

Lindsey, J.; Litwin-Kumar, A.

10.1101/2022.12.08.519638 — neuroscience — Posted on 2024-02-28

179 HB-EGF and EGF infusion following CNS demyelination mitigates age-related decline in regeneration of oligodendrocytes from neural precursor cells originating in the ventricular-subventricular zone

Moradi, K.; Mitew, S.; Xing, Y. L.; Merson, T. D.

10.1101/2024.02.26.582092 — neuroscience — Posted on 2024-02-28

180 Solving the where problem in neuroanatomy: a generative framework with learned mappings to register multimodal, incomplete data into a reference brain

Tward, D. J.; Gray, B. D. P.; Li, X.; Huo, B.; Banerjee, S.; Savoia, S.; Mezias, C.; Das, S.; Miller, M.; Mitra, P. P.

10.1101/2020.03.22.002618 — neuroscience — Posted on 2024-02-28

181 A method for correcting systematic error in PO2 measurement to improve measures of oxygen supply capacity

Timpe, A. W.; Seibel, B. A.

10.1101/2024.02.25.581970 — physiology — Posted on 2024-02-28

182 Unsupervised segmentation of 3D microvascular photoacoustic images using deep generative learning

Sweeney, P. W.; Hacker, L.; Lefebvre, T. L.; Brown, E. L.; Gröhl, J.; Bohndiek, S. E.

10.1101/2023.04.30.538453 — biophysics — Posted on 2024-02-28

183 A biophysical minimal model to investigate age-related changes in CA1 pyramidal cell electrical activity

McKiernan, E. C.; Herrera-Valdez, M. A.; Marrone, D. F.

10.1101/2022.07.01.498486 — biophysics — Posted on 2024-02-28

184 Geometric Quantification of Cell Phenotype Transition Manifolds with Information Geometry

Huang, M.; Ying, J.; Wang, Y.; Zhou, H.; Zhang, L.; Wang, W.

10.1101/2023.12.28.573500 — biophysics — Posted on 2024-02-28

185 MAPLE: A Hybrid Framework for Multi-Sample Spatial Transcriptomics Data

Jeon, H.; Allen, C.; Ovando-Ricardez, J. A.; Chang, Y.; Rosas, L.; Vanegas, N.-D. P.; Cheng, H.; Xie, J.; Wang, C.; Mora, A. L.; Rojas, M.; Ma, Q.; Chung, D.

10.1101/2022.02.28.482296 — bioinformatics — Posted on 2024-02-28

186 Exploring the conformational ensembles of protein-protein complex with transformer-based generative model

Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.

10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-02-28

187 Prominin 1 and Tweety Homology 1 both induce extracellular vesicle formation

Bell, T. A.; Luce, B. E.; Hakim, P.; Ananda, V. Y.; Dardari, H.; Nguyen, T. H.; Monshizadeh, A.; Chao, L. H.

10.1101/2023.11.08.566258 — biochemistry — Posted on 2024-02-28

188 Getting More by Asking for Less: Linking Species Interactions to Species Co-Distributions in Metacommunities

Barbier, M.; Bunin, G.; Leibold, M. A.

10.1101/2023.06.04.543606 — ecology — Posted on 2024-02-28

189 Spatial Multiomics Reveal the Role of Wnt Modulator, Dkk2, in Palatogenesis

Oliver Pina, J.; Raju, R.; Roth, D. M.; Winchester, E. W.; Padilla, C.; Iben, J.; Faucz, F. R.; Cotney, J. L.; D'Souza, R. N.

10.1101/2023.05.16.541037 — developmental biology — Posted on 2024-02-28

190 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids

Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Ren, W.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.

10.1101/2023.04.25.538102 — cell biology — Posted on 2024-02-28

191 Pathway-enhanced Transformer-based model for robust enumeration of cell types from the cell-free transcriptome

Yan, S.; Tian, X.; Qin, Y.; Li, J.; Yang, T.; Yu, D.; Liu, W.; Sun, J.; Hu, C.; Zhou, Q.; Liu, Z.; Wang, W.-J.

10.1101/2024.02.28.582494 — bioinformatics — Posted on 2024-02-28

192 A single-cell transcriptomics atlas for the parasitic nematode Heligmosomoides bakeri: Extrapolating model organism information to non-model systems

Pollo, S. M. J.; Liu, H.; Leon Coria, A.; Rosin, N.; Labit, E.; Biernaskie, J.; Finney, C. A. M.; Wasmuth, J. D.

10.1101/2024.02.27.582282 — developmental biology — Posted on 2024-02-28

193 TrajectoryGeometry suggests cell fate decisions involve branches rather than bifurcations

Laddach, A. C.; Shapiro, M.

10.1101/2024.02.26.582231 — developmental biology — Posted on 2024-02-28

194 Co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase and a cytosine base editor greatly increases transfection and editing rates in Leishmania species

May, N. H.; Schmid, A.; Meiser, E.; Beneke, T.

10.1101/2024.02.28.582587 — molecular biology — Posted on 2024-02-28

195 A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity

Boggess, S. C.; Gandhi, V.; Tsai, M.-C.; Chou, J. Y.-Y.; Hu, X.; Yadanar, L.; Teyssier, N.; Eidenschenk, C.; Hanson, J. E.; Tian, R.; Kampmann, M.

10.1101/2024.02.28.582546 — neuroscience — Posted on 2024-02-28

196 Parameter Estimation in Brain Dynamics Models from Resting-State fMRI Data using Physics-Informed Neural Networks

Sotero, R. C.; Sanchez-Bornot, J. M.; Shaharabi-Farahani, I.

10.1101/2024.02.27.582428 — neuroscience — Posted on 2024-02-28

197 MarmoPose: A Deep Learning-Based System for Real-time Multi-Marmoset 3D Pose Trackingp

Cheng, C.; Huang, Z.; Zhang, R.; Huang, G.; Wang, H.; Tang, L.; Wang, X.

10.1101/2024.02.27.582429 — animal behavior and cognition — Posted on 2024-02-28

198 Virological traits of the SARS-CoV-2 BA.2.87.1 lineage

Zhang, L.; Dopfer-Jablonka, A.; Nehlmeier, I.; Kempf, A.; Graichen, L.; Calderon Hampel, N.; Cossmann, A.; Stankov, M. V.; Morillas Ramos, G.; Schulz, S. R.; Jaeck, H.-M.; Behrens, G. M. N.; Poehlmann, S.; Hoffmann, M.

10.1101/2024.02.27.582254 — molecular biology — Posted on 2024-02-28

199 Prevalence of Class 1 integron in disease-causing carbapenem-resistant Escherichia coli in a tertiary hospital in Kathmandu, Nepal

Thapa, S.; Shrestha, B.; Shrestha, M.; Pokhrel, Y.; Tuladhar, R.; Jauneikaite, E.; Joshi, D. R.

10.1101/2024.02.28.582515 — microbiology — Posted on 2024-02-28

200 Drought influences the fungal community structure, diversity, and functionality inhabiting the grapevine xylem and enhances the abundance of Phaeomoniella chlamydospora

Leal, C.; Bujanda, R.; Carbone, M. J.; Kiss, T.; Eichmeier, A.; Gramaje, D.; Maldonado, M. M.

10.1101/2024.02.28.582583 — microbiology — Posted on 2024-02-28

201 Transcriptomic characterization of recombinant Clostridium beijerinckii NCIMB 8052 expressing methylglyoxal synthase and glyoxal reductase from Clostridium pasteurianum ATCC 6013

Kumar, S.; Agyeman-Duah, E.; Ujor, V. C.

10.1101/2024.02.27.582317 — microbiology — Posted on 2024-02-28

202 Novel misos shape distinct microbial ecologies: opportunities for flavourful sustainable food innovation

Kothe, C. I.; Caroe, C.; Mazel, F.; Zilber, D.; Cruz-Morales, P.; Mohellibi, N.; Evans, J.

10.1101/2024.02.28.582453 — microbiology — Posted on 2024-02-28

203 Post-transcriptional regulation of the MiaA prenyl transferase by CsrA and the small RNA CsrB in E. coli

Aubee, J. I.; Williams, K.; Adigun, A.; Olusanya, O.; Nurse, J.; Thompson, K. M.

10.1101/2024.02.28.582573 — microbiology — Posted on 2024-02-28

204 Recalibration of macrophage lipid metabolism underlies intracellular bacterial neuroinvasion

wu, h.

10.1101/2024.02.28.582462 — microbiology — Posted on 2024-02-28

205 Low microbial abundance and community diversity within the egg capsule of the oviparous cloudy catshark (Scyliorhinus torazame) during oviposition

Takagi, W.; Masuda, A.; Shimoyama, K.; Tokunaga, K.; Hyodo, S.; Sato-Takabe, Y.

10.1101/2024.02.28.582473 — microbiology — Posted on 2024-02-28

206 Quantification and modeling of grapevine yield loss as a function of the severity of downy mildew on foliage and cluster

Fabre, F.; Delbac, L.; Poeydebat, C.; Zaffaroni, M.

10.1101/2024.02.28.582447 — microbiology — Posted on 2024-02-28

207 Liquid phase electron microscopy of bacterial ultrastructure.

Caffrey, B. J.; Pedrazo-Tardajos, A.; Liberti, E.; Gaunt, B.; Kim, J. S.; Kirkland, A. I.

10.1101/2024.02.27.580996 — microbiology — Posted on 2024-02-28

208 The amino acid permease Byc1 is involved in calcineurin-dependent thermos-tolerance in Cryptococcus neoformans

Lee, K.-T.; Giner, M.; Bahn, D.; Cornitius, C. P.; Lee, S. C.

10.1101/2024.02.27.582329 — microbiology — Posted on 2024-02-28

209 Transient inhibition of cell division in competent pneumococcal cells results from deceleration of the septal peptidoglycan complex

Juillot, D.; Billaudeau, C.; Barbotin, A.; Lablaine, A.; Mortier-Barriere, I.; Polard, P.; Campo, N.; LOPEZ, R. C.

10.1101/2024.02.28.582556 — microbiology — Posted on 2024-02-28

210 The S2 subunit of spike encodes diverse targets for functional antibody responses to SARS-CoV-2

Guenthoer, J.; Garrett, M. E.; Lilly, M.; Depierreux, D. M.; Ruiz, F.; Chi, M.; Stoddard, C. I.; Chohan, V.; Sung, K.; Ralph, D.; Chu, H. Y.; Matsen, F. A.; Overbaugh, J.

10.1101/2024.02.26.582219 — immunology — Posted on 2024-02-28

211 A nonlinear code for event probability in the human brain

Foucault, C.; Bounmy, T.; Demortain, S.; Thirion, B.; Eger, E.; MEYNIEL, F.

10.1101/2024.02.28.582455 — neuroscience — Posted on 2024-02-28

212 Reconstructing Voice Identity from Noninvasive Auditory Cortex Recordings

Lamothe, C.; Thoret, E.; Trapeau, R.; Giordano, B. L.; Sein, J.; Takerkart, S.; Ayache, S.; Artieres, T.; Belin, P.

10.1101/2024.02.27.582302 — neuroscience — Posted on 2024-02-28

213 The Douglas Bell Canada Brain Bank Post-mortem Brain Imaging Protocol

Dadar, M.; Sanches, L.; Fouquet, J.; Moqadam, R.; Alasmar, Z.; Mirault, D.; Maranzano, J.; Mechawar, N.; Chakravarty, M.; Zeighami, Y.

10.1101/2024.02.27.582303 — neuroscience — Posted on 2024-02-28

214 Neuromodulatory effects on synchrony and network reorganization in networks of coupled Kuramoto oscillators.

Aktay, S.; Sander, L.; Zochowski, M.

10.1101/2024.02.27.582261 — neuroscience — Posted on 2024-02-28

215 Synchronized photoactivation of T4K rhodopsin causes a chromophore-dependent retinal degeneration that moderated by interaction with phototransduction cascade components.

Tam`, B. M.; Burns, P. L.; Chiu, C. N.; Moritz, O. L.

10.1101/2024.02.27.582380 — neuroscience — Posted on 2024-02-28

216 Linking neuronal avalanches with oscillatory and broadband 1/f activities in the resting human brain

Dellavale, D.; Rabuffo, G.; Lopez, E. T.; Romano, A.; Sorrentino, P.

10.1101/2024.02.28.582552 — neuroscience — Posted on 2024-02-28

217 Distinct Dendritic Morphological Changes in the Nucleus Accumbens of Microbiota-deficient Male Mice

Garcia-Cabrerizo, R.; Viola, M. F.; Luczynski, P.; Clarke, G.; Cryan, J. F.

10.1101/2024.02.27.582301 — neuroscience — Posted on 2024-02-28

218 Interneuron loss and microglia activation by transcriptome analyses in the basal ganglia of Tourette syndrome

Wang, Y.; Fasching, L.; Wu, F.; Huttner, A.; Berretta, S.; Roberts, R.; Leckman, J. F.; Abyzov, A.; Vaccarino, F. M.

10.1101/2024.02.28.582504 — neuroscience — Posted on 2024-02-28

219 Drug inhibition and substrate alternating flipping mechanisms of human VMAT2

Wei, F.; Liu, H.; Zhang, W.; Wang, J.; Zhang, Y.

10.1101/2024.02.28.582500 — neuroscience — Posted on 2024-02-28

220 Sources of uncertainty in human stereo-depth perception in natural images and scenes

White, D. N.; Burge, J.

10.1101/2024.02.27.582383 — neuroscience — Posted on 2024-02-28

221 Statistical learning of incidental perceptual regularities induces sensory conditioned cortical responses

Greco, A.; D'Alessandro, M.; Gallitto, G.; Rastelli, C.; Braun, C.; Caria, A.

10.1101/2024.02.28.582496 — neuroscience — Posted on 2024-02-28

222 A non-Hebbian code for episodic memory

Pang, R.; Recanatesi, S.

10.1101/2024.02.28.582531 — neuroscience — Posted on 2024-02-28

223 Force, angle, and velocity parameters of finger movements are reflected in corticospinal excitability

Brandt, I. M.; Lundbye-Jensen, J.; Grunbaum, T.; Christensen, M. S.

10.1101/2024.02.28.582459 — neuroscience — Posted on 2024-02-28

224 Monkey Prefrontal Cortex Learns to Minimize Sequence Prediction Error

Cheng, H.; Chafee, M.; Blackman, R. K.; Brown, J.

10.1101/2024.02.28.582611 — neuroscience — Posted on 2024-02-28

225 Robust variability of grid cell properties within individual grid modules enhances encoding of local space

Redman, W. T.; Acosta-Mendoza, S.; Wei, X.-X.; Goard, M. J.

10.1101/2024.02.27.582373 — neuroscience — Posted on 2024-02-28

226 Linking Neural Manifolds to Principles of Circuit Structure

Pezon, L.; Schmutz, V.; Gerstner, W.

10.1101/2024.02.28.582565 — neuroscience — Posted on 2024-02-28

227 A computational and multi-brain signature for aberrant social coordination in schizophrenia

Wang, Y.-J.; Wen, Y.; Zheng, L.; Chen, J.; Lin, Z.; Pan, Y.

10.1101/2024.02.27.582430 — neuroscience — Posted on 2024-02-28

228 The effect of molnupiravir and nirmatrelvir on SARS-CoV-2 genome diversity in infected and immune suppressed mice

Penrice-Randal, R.; Bentley, E. G.; Sharma, P.; Kirby, A.; Donovan-Banfield, I.; Kipar, A.; Mega, D. F.; Bramwell, C.; Sharp, J.; Owen, A.; Hiscox, J. A.; Stewart, J. P.

10.1101/2024.02.27.582110 — pharmacology and toxicology — Posted on 2024-02-28

229 Carboxylated graphene: A novel approach for enhanced IgA-SARS-CoV-2 electrochemical biosensing

Freire, L. d. S.; Ruzo, C. M.; Salgado, B. B.; Gandarilla, A.; Barcelay, Y. R.; Tavares, A. P. M.; Nobre, F. X.; Lalwani, P.; Astofi-Filho, S.; Brito, W.

10.1101/2024.02.27.582131 — bioengineering — Posted on 2024-02-28

230 Secondary structure of the SARS-CoV-2 genome is predictive of nucleotide substitution frequency

Hensel, Z.

10.1101/2024.02.27.581995 — molecular biology — Posted on 2024-02-28

231 Inhibition of SARS-CoV-2 infection by Porphyromonas gingivalis and the oral microbiome

Bontempo, A.; Chirino, A.; Heidari, A.; Lugo, A.; Shindo, S.; Pastore, M. R.; Antonson, S.; Godoy, C.; Nichols, F.; Potempa, J.; Davey, M.; Kawai, T.; Cayabyab, M.

10.1101/2024.02.27.582258 — microbiology — Posted on 2024-02-28

232 The ER-resident Ras Inhibitor 1 (Eri1) of Candida albicans inhibits hyphal morphogenesis via the Ras-independent cAMP-PKA pathway

Komath, S. S.; Sethi, S. C.; Bharati, M.; Yadav, U.; Kumar, Y.

10.1101/2024.02.28.582498 — microbiology — Posted on 2024-02-28

233 Tissue-specific and endogenous protein labeling with split fluorescent proteins

Ligunas, G. D.; Paniagua, G.; LaBelle, J.; Ramos-Martinez, A.; Shen, K.; Gerlt, E. H.; Aguilar, K.; Nguyen, A.; Materna, S. C.; Woo, S.

10.1101/2024.02.28.581822 — developmental biology — Posted on 2024-02-28

234 CyanoTag: Discovery of protein function facilitated by high-throughput endogenous tagging in a photosynthetic prokaryote

Perrin, A.; Dowson, M.; Dowle, A.; Calder, G.; Springthorpe, V.; Zhao, G.; Mackinder, L.

10.1101/2024.02.28.582475 — microbiology — Posted on 2024-02-28

235 Unraveling the Interplay between Phytochemicals and Rhizosphere Bacteria in Ficus racemosa

Balkrishna, A.; Kaushik, P.; Ghosh, S.; Arya, V.

10.1101/2024.02.27.582418 — microbiology — Posted on 2024-02-28

236 Pre-challenge gut microbial signature predicts RhCMV/SIV vaccine efficacy in rhesus macaques

Brochu, H. N.; Smith, E.; Jeong, S.; Carlson, M.; Hansen, S. G.; Tisoncik-Go, J.; Law, L.; Picker, L. J.; Gale, M.; Peng, X.

10.1101/2024.02.27.582186 — microbiology — Posted on 2024-02-28

237 Designed mosaic nanoparticles enhance cross-reactive immune responses in mice

Wang, E.; Cohen, A. A.; Caldera, L. F.; Keeffe, J. R.; Rorick, A. V.; Aida, Y. M.; Gnanapragasam, P. N. P.; Bjorkman, P. J.; Chakraborty, A. K.

10.1101/2024.02.28.582544 — immunology — Posted on 2024-02-28

238 Attenuated replication and damaging effects of SARS-CoV-2 Omicron in an intestinal epithelial barrier model

Volcic, M.; Nchioua, R.; Pastorio, C.; Zech, F.; Read, C.; Walther, P.; Kirchhoff, F.

10.1101/2024.02.28.582510 — immunology — Posted on 2024-02-28

239 Characterization of the three-dimensional synaptic and mitochondrial nanoarchitecture within glutamatergic synaptic complexes in postmortem human brain via focused ion beam-scanning electron microscopy

Glausier, J. R.; Bouchet-Marquis, C.; Maier, M.; Banks-Tibbs, T.; Wu, K.; Ning, J.; Melchitzky, D.; Lewis, D. A.; Freyberg, Z. A.

10.1101/2024.02.26.582174 — neuroscience — Posted on 2024-02-28

240 Reactivated past decisions repel early sensory processing and attract late decision-making

Luo, M.; Zhang, H.; Luo, H.

10.1101/2024.02.26.582221 — neuroscience — Posted on 2024-02-28

241 Neural pathways and computations that achieve stable contrast processing tuned to natural scenes

Gür, B.; Ramirez, L.; Cornean, J.; Thurn, F.; Molina-Obando, S.; Ramos-Traslosheros, G.; Silies, M.

10.1101/2024.02.27.582271 — neuroscience — Posted on 2024-02-28

242 Linewidth-related bias in modelled concentration estimates from GABA-edited 1H-MRS

Craven, A. R.; Bell, T. K.; Ersland, L.; Harris, A. D.; Hugdahl, K.; Oeltzschner, G.

10.1101/2024.02.27.582249 — neuroscience — Posted on 2024-02-28

243 Glucose appetition in C57BL/6J mice: Influence of nonnutritive sweetener experience, food deprivation state and sex differences

Sclafani, A.; Ackroff, K.

10.1101/2024.02.27.582331 — neuroscience — Posted on 2024-02-28

244 MVComp toolbox: MultiVariate Comparisons of brain MRI features accounting for common information across metrics

Tremblay, S. A.; Alasmar, Z.; Pirhadi, A.; Carbonell, F.; Iturria-Medina, Y.; Gauthier, C. J.; Steele, C. J.

10.1101/2024.02.27.582381 — neuroscience — Posted on 2024-02-28

245 Absence seizures and sleep abnormalities in a rat model of GRIN2B neurodevelopmental disorder

Hristova, K.; Fasol, M. C.; McLaughlin, N.; Nawaz, S.; Taskiran, M.; Buller-Peralta, I.; Bassi, A.; Ocampo-Garces, A.; Escudero, J.; Kind, P. C.; Gonzalez-Sulser, A.

10.1101/2024.02.27.582289 — neuroscience — Posted on 2024-02-28

246 New approaches to the Single-Interval Adjustment Matrix (SIAM) Yes-No task

Shepherd, D.; Hautus, M. J.

10.1101/2024.02.27.582322 — neuroscience — Posted on 2024-02-28

247 Proportion and distribution of neurotransmitter-defined cell types in the ventral tegmental area and substantia nigra pars compacta

Conrad, W. S.; Oriol, L.; Faget, L.; Hnasko, T. S.

10.1101/2024.02.28.582356 — neuroscience — Posted on 2024-02-28

248 Bringing astrocytes into the spotlight of electrical brain stimulation

Aroso, M.; Castro, D.; Silva, S. C.; Aguiar, P.

10.1101/2024.02.28.582466 — neuroscience — Posted on 2024-02-28

249 Agency accounts for the effect of FB transparency onmotor imagery neurofeedback performance

Dussard, C.; Pillette, L.; Dumas, C.; Pierrieau, E.; Hugueville, L.; Lau, B.; Jeunet, C.; George, N.

10.1101/2024.02.27.582270 — neuroscience — Posted on 2024-02-28

250 Decoding Music-Evoked Valence and Arousal: Unraveling the Neural Correlates of Naturalistic Music Characteristics through fMRI

Sayal, A.; Guedes, A. G.; Almeida, I.; Pereira, D. J.; Lima, C.; Panda, R.; Paiva, R. P.; Sousa, T.; Castelo-Branco, M.; Bernardino, I.; Direito, B.

10.1101/2024.02.27.582309 — neuroscience — Posted on 2024-02-28

251 Decoding Motor Excitability in TMS using EEG-Features:An Exploratory Machine Learning Approach

Haxel, L.; Belardinelli, P.; Ermolova, M.; Humaidan, D.; Macke, J. H.; Ziemann, U.

10.1101/2024.02.27.582361 — neuroscience — Posted on 2024-02-28

252 Diet-induced metabolic and immune impairments are sex-specifically modulated by soluble TNF signaling in the 5xFAD mouse model of Alzheimers disease

de Sousa Rodrigues, M. E.; Bolen, M. L.; Blackmer-Raynolds, L.; Schwartz, N.; Chang, J.; Tansey, M. G.; Sampson, T. R.

10.1101/2024.02.28.582516 — neuroscience — Posted on 2024-02-28

253 GLP-1 receptor agonism ameliorates Parkinsons disease through modulation of neuronal insulin signalling and glial suppression

Athauda, D.; Evans, J. R.; Sanchez, L.; Virdi, G.; Lopez Garcia, P.; Wernick, A.; Wagen, A.; D'Sa, K.; Lachica, J.; Strohbuecker, S.; Vecchi, G.; Leighton, C.; Saleeb, R. S.; OShaughnessy, J.; Toomey, C.; Vijiaratnam, N.; Girges, C.; Li, Y.; Mustapic, M.; Ismail, K.; Davies, M.; Kapogiannis, D.; Choi, M. L.; Ryten, M.; Horrocks, M. H.; Greig, N. H.; Foltynie, T.; Gandhi, S.

10.1101/2024.02.28.582460 — neuroscience — Posted on 2024-02-28

254 PhysMAP - interpretable in vivo neuronal cell type identification using multi-modal analysis of electrophysiological data

Lee, E. K.; Gul, A.; Heller, G.; Lakunina, A.; Jaramillo, S.; Przytycki, P.; Chandrasekaran, C.

10.1101/2024.02.28.582461 — neuroscience — Posted on 2024-02-28

255 Using a Foerster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain

Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.

10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-02-28

256 Hippocampal purinergic P2X7 receptor level is increased in Alzheimer's disease patients, and associated with amyloid and tau pathologies

Maschio, C.; Wang, J.; Maheshwari, U.; Keller, A.; Rominger, A.; Konietzko, U.; Hock, C.; Nitsch, R. M.; Nordberg, A.; Ni, R.

10.1101/2024.02.28.582443 — neuroscience — Posted on 2024-02-28

257 Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning.

Venditto, S. J. C.; Miller, K. J.; Brody, C. D.; Daw, N. D.

10.1101/2024.02.28.582617 — neuroscience — Posted on 2024-02-28

258 L-Type calcium channels and TRPC3 channels shape brain pericyte calcium signaling and hemodynamics throughout the arteriole to capillary network in vivo

Meza-Resillas, J.; O'Hara, F.; Kaushik, S.; Stobart, M. J.; Ahmadpour, N.; Kantroo, M.; Shabanipour, S.; Del Rosario, J.; Rodriguez, M. C.; Koval, D.; Glueck, C.; Weber, B.; Stobart, J. L.

10.1101/2024.02.27.582351 — neuroscience — Posted on 2024-02-28

259 Failed stopping transiently suppresses the electromyogram in task-irrelevant muscles

Mills, I.; Fisher, M.; Wadsley, C. G.; Greenhouse, I.

10.1101/2024.02.27.582386 — neuroscience — Posted on 2024-02-28

260 A Drug Screening Platform for Protein Expression Levels in Neurological Disorders

Emran, F.; Kays, I.; Lo, C.-A.; Li, Y.; Chen, B. E.

10.1101/2024.02.27.582434 — neuroscience — Posted on 2024-02-28

261 Electrophysiological dynamics of cognitive control networks in human memory and replication across four experiments

Das, A.; Menon, V.

10.1101/2024.02.28.582593 — neuroscience — Posted on 2024-02-28

262 MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer

Klingbeil, O.; Skopelitis, D.; Tonelli, C.; Alpsoy, A.; Minicozzi, F.; Aggarwal, D.; Russo, S.; Ha, T.; Demerdash, O. E.; Spector, D. L.; Tuveson, D. A.; Cifani, P.; Vakoc, C. R.

10.1101/2024.02.26.582171 — cancer biology — Posted on 2024-02-28

263 Heterogeneity and evolution of DNA mutation rates in microsatellite stable colorectal cancer

Grassi, E.; Vurchio, V.; Cresswell, G. D.; Catalano, I.; Lupo, B.; Sassi, F.; Galimi, F.; Borgato, S.; Ferri, M.; Viviani, M.; Pompei, S.; Urgese, G.; Chen, B.; Zanella, E. R.; Cottino, F.; Bardelli, A.; Cosentino Lagormarsino, M.; Sottoriva, A.; Trusolino, L.; Bertotti, A.

10.1101/2024.02.26.582054 — cancer biology — Posted on 2024-02-28

264 Deciphering rapid cell signaling and control of cell motility by reverse opto-chemical engineering

Hamzeh, H.; Gong, A.; Balbach, M.; Fridman, D.; Koerschen, H. G.; Pascal, R.; Lavryk, F.; Rennhack, A.; Seifert, R.; Hernandez-Clavijo, A.; Pifferi, S.; Dusend, V.; Fleischmann, B.; Sasse, P.; Menini, A.; Friedrich, B. M.; Alvarez, L.; Kaupp, U. B.

10.1101/2024.02.26.582067 — biophysics — Posted on 2024-02-28

265 Cluster decomposition-based anomaly detection for rare cell identification in single-cell expression data

Xu, Y.; Wang, S.; Li, H.-D.; Feng, Q.; Li, Y.; Wang, J.

10.1101/2024.02.25.581975 — bioinformatics — Posted on 2024-02-28

266 STCC: consensus clustering enhances spatial domain detection for spatial transcriptomics data

Hu, C.; Wei, N.; Yang, J.; Wu, H.-J.; Zheng, X.

10.1101/2024.02.25.581996 — bioinformatics — Posted on 2024-02-28

267 Evaluating generalizability of artificial intelligence models for molecular datasets

Ektefaie, Y.; Shen, A.; Bykova, D.; Marin, M.; Zitnik, M.; Farhat, M. R.

10.1101/2024.02.25.581982 — bioinformatics — Posted on 2024-02-28

268 Helical grooves on the surfaces of microtrichia in European Hornets: Functional significance for antipodal relation between right and left hindwings

Inoue, S.; Sato, H.; Yamagishi, A.

10.1101/2024.02.25.582003 — bioengineering — Posted on 2024-02-28

269 Mitigating Stress: Exploring how our feet change shape with size

Treherne, P.; Lee, E. C.; Rainbow, M. J.; Kelly, L. A.

10.1101/2024.02.25.581965 — evolutionary biology — Posted on 2024-02-28

270 A dual strategy - in vitro and in silico - to evaluate human antitetanus mAbs addressing their potential protective action on TeNT endocytosis in primary rat neuronal cells

Lima, C. P.; Barreiros, G. M.; Oliveira, A. S.; Souza, M. M.; Manieri, T. M.; Moro, A. M.

10.1101/2024.02.25.582016 — immunology — Posted on 2024-02-28

271 CD34-positive monocytes are highly susceptible to HIV-1

Takahashi, N.; Noyori, O.; Komohara, Y.; Eltalkhawy, Y. M.; Hirayama, M.; Yoshida, R.; Nakayama, H.; Kuroda, M. J.; Nomura, T.; Ishii, H.; Matano, T.; Gatanaga, H.; Oka, S.; Takiguchi, M.; Suzu, S.

10.1101/2024.02.26.582226 — immunology — Posted on 2024-02-28

272 Perinatal Brain Injury Triggers Niche-Specific Changes to Cellular Biogeography

Tahmasian, N.; Feng, M. Y.; Arbabi, K.; Rusu, B.; Cao, W.; Kukreja, B.; Lubotzky, A.; Wainberg, M.; Tripathy, S.; Kalish, B. T.

10.1101/2024.02.25.581974 — neuroscience — Posted on 2024-02-28

273 Stable sequential dynamics in prefrontal cortex represents subjective estimation of time

Li, Y.; Yin, W.; Li, J.; Zhou, S.; Ma, C.-L.; Yuan, P.; Li, B.-M.

10.1101/2024.02.26.582071 — neuroscience — Posted on 2024-02-28

274 Evaluation of common in vitro assays for the prediction of oral bioavailability and hepatic metabolic clearance in humans

Fagerholm, U.

10.1101/2024.02.25.581937 — pharmacology and toxicology — Posted on 2024-02-28

275 PocketGen: Generating Full-Atom Ligand-Binding Protein Pockets

Zaixi, Z.; Shen, W.; Liu, Q.; Zitnik, M.

10.1101/2024.02.25.581968 — bioinformatics — Posted on 2024-02-28

276 CRE mice exhibit hyperactive and impulsive behavior affecting their learning and retention performances

Desor, F.; El Hajj, A.; Herzine, A.; Djelti, F.; Bombail, V.; Denis, I.; Oster, T.; Lanhers, M.-C.; Malaplate, C.; Yen, F. T.; Claudepierre, T.

10.1101/2024.02.27.582228 — animal behavior and cognition — Posted on 2024-02-28

277 A new look at functional beta diversity

Ricotta, C.; Pavoine, S.

10.1101/2024.02.25.580632 — ecology — Posted on 2024-02-28

278 Receptor tyrosine kinases CAD96CA and FGFR1 function as the cell membrane receptors of insect juvenile hormone

Li, Y.-X.; Kang, X.-L.; Li, Y.-L.; Wang, X.-P.; Yan, Q.; Wang, J.-X.; Zhao, X.-F.

10.1101/2024.02.27.582377 — developmental biology — Posted on 2024-02-28

279 Supplementary motor area disinhibition during motor sequence learning: A TMS-EEG study

Thong, S.; Doery, E.; Biabani, M.; Rogasch, N. C.; Chong, T. T.- J.; Hendrikse, J.; Coxon, J. P.

10.1101/2024.02.26.581077 — neuroscience — Posted on 2024-02-28

280 Blind individuals' enhanced ability to sense their own heartbeat is related to the thickness of their occipital cortex

Stroh, A. L.; Radziun, D.; Korczyk, M.; Crucianelli, L.; Ehrsson, H. H.; Szwed, M.

10.1101/2024.02.26.581908 — neuroscience — Posted on 2024-02-28

281 in silico transcriptome dissection of neocortical excitatory neurogenesis via joint matrix decomposition and transfer learning

Sonthalia, S.; Li, G.; Blanco, X. M.; Casella, A.; Liu, J.; Stein-O'Brien, G.; Caffo, B.; Adkins, S.; Orvis, J.; Hertzano, R.; Mahurkar, A.; Gillis, J. A.; Werner, J.; Ma, S.; Micali, N.; Sestan, N.; Rakic, P.; Baro, G. S.; Ament, S. A.; Colantuoni, C.

10.1101/2024.02.26.581612 — neuroscience — Posted on 2024-02-28

282 A model for cortical activity sequences

Lehr, A. B.; Erzmann, F.; Michaelis, C.; Nowak, J.; Gail, A.; Kumar, A.; Tetzlaff, C.

10.1101/2024.02.25.581959 — neuroscience — Posted on 2024-02-28

283 The DREAM implant: A Lightweight, Modular and Cost-Effective Implant System for Chronic Electrophysiology in Head-fixed and Freely Behaving Mice

Schroeder, T.; Taylor, R.; Abd El Hay, M.; Nemri, A.; Franca, A.; Battaglia, F.; Tiesinga, P.; Schoelvinck, M. L.; Havenith, M. N.

10.1101/2024.02.26.582029 — neuroscience — Posted on 2024-02-28

284 A parabrachial hub for the prioritization of survival behavior

Goldstein, N.; Maes, A.; Allen, H. N.; Nelson, T. S.; Kruger, K. A.; Kindel, M.; Smith, N. K.; Carty, J. R.; Villari, R. E.; Cho, E.; Marble, E. L.; Khanna, R.; Taylor, B. K.; Kennedy, A.; Betley, J. N.

10.1101/2024.02.26.582069 — neuroscience — Posted on 2024-02-28

285 Evidence for shallow cognitive maps in schizophrenia

Karagoz, A. B.; Moran, E. K.; Barch, D.; Kool, W.; Reagh, Z. M.

10.1101/2024.02.26.582214 — neuroscience — Posted on 2024-02-28

286 Disentangling Mnemonic Metacognition from Confidence by Communication between the Precuneus and Hippocampus

Pan, K.; Guo, X.; Zheng, Z.; Zhu, Z.; Wu, H.; Zhu, J.; Santos-Pata, D.; Zhang, J.; Kwok, S. C.; Jiang, H.

10.1101/2024.02.26.581526 — neuroscience — Posted on 2024-02-28

287 Hippocampal DNA methylation promotes memory persistence by facilitating systems consolidation and cortical engram stabilisation.

Kupke, J.; Loizou, S.; Bengtson, C. P.; Sticht, C.; Oliveira, A. M. M.

10.1101/2024.02.25.581942 — neuroscience — Posted on 2024-02-28

288 Computational joint action: dynamical models to understand the development of joint coordination

De Vicariis, C.; Bandini, L.; Sanguineti, V.; Ravaschio, E.; Chackochan, V. T.

10.1101/2024.02.25.582011 — neuroscience — Posted on 2024-02-28

289 A new interesting and unidentified Schmidtea species in Romania (Platyhelminthes, Tricladida, Dugesiidae)

Anda Felicia, B.

10.1101/2024.02.26.582039 — zoology — Posted on 2024-02-28

290 The lipidome of posttraumatic stress disorder

Bhargava, A.; Knapp, J. D.; Fiehn, O.; Neylan, T. C.; Inslicht, S. S.

10.1101/2024.02.23.581833 — systems biology — Posted on 2024-02-28

291 Differential Responses of Dynamic and Entropic Aging Factors to Longevity Interventions

Perevoshchikova, K.; Fedichev, P. O.

10.1101/2024.02.25.581928 — systems biology — Posted on 2024-02-28

292 Holimap: an accurate and efficient method for solving stochastic gene network dynamics

Jia, C.; Grima, R.

10.1101/2024.02.25.581947 — systems biology — Posted on 2024-02-28

293 A targetable PREX2/RAC1/PI3Kβ signalling axis confers resistance to clinically relevant therapeutic approaches in melanoma

Ford, C. A.; Koludrovic, D.; Centeno, P. P.; Foth, M.; Tsonou, E.; Vlahov, N.; Sphyris, N.; Gilroy, K.; Bull, C.; Nixon, C.; Serrels, B.; Munro, A. F.; Dawson, J. C.; Carragher, N. O.; Pavet, V.; Hornigold, D. C.; Dunne, P. D.; Downward, J.; Welch, H. C. E.; Barry, S. T.; Sansom, O. J.; Campbell, A. D.

10.1101/2024.02.26.580534 — cancer biology — Posted on 2024-02-28

294 Data-driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Nourbakhsh, M.; Tom, N.; Schroeder Lassen, A.; Brasch Lind Petersen, H.; Kristoffer Stoltze, U.; Wadt, K.; Schmiegelow, K.; Tiberti, M.; Papaleo, E.

10.1101/2024.02.26.582026 — cancer biology — Posted on 2024-02-28

295 Patters of Intra-Clustering Analysis Reveal Hidden Oncogenic Relations

Choudalakis, S.; Kastis, G.; Dikaios, N.

10.1101/2024.02.26.582027 — bioinformatics — Posted on 2024-02-28

296 Iterative Bleaching Extends Multiplexity (IBEX) imaging facilitates simultaneous identification of all cell types in the vertebrate retina

Kothurkar, A.; Patient, G. S.; Noel, N. C. L.; Chu, C. J.; MacDonald, R. B.

10.1101/2024.02.28.582563 — developmental biology — Posted on 2024-02-28

297 Bycatch mitigation of endangered marine life

Villafafila, M.; Carpio, A.; Rivas, M. L.

10.1101/2024.02.20.581169 — developmental biology — Posted on 2024-02-28

298 Cell morphogenesis via shape-guided self-propelled treadmilling actin waves

Yagami, K.; Baba, K.; Misu, S.; Katsuno-Kambe, H.; Minegishi, T.; Okano, K.; Sakumura, Y.; Hosokawa, Y.; Inagaki, N.

10.1101/2024.02.28.582450 — cell biology — Posted on 2024-02-28

299 Circulating plasma fibronectin affects normal adipose tissue insulin sensitivity and adipocyte differentiation

Kaartinen, M. T.; Mahmoodi, M.; Dahaghi, E. M.; Nabavi, M.-H.; Penalva, Y.; Gosaine, A.; Murshed, M.; Couldwell, S.; Munter, L.

10.1101/2024.02.28.582553 — cell biology — Posted on 2024-02-28

300 The 5-HT7 receptor antagonist SB 269970 ameliorates maternal fluoxetine exposure-induced impairment of synaptic plasticity in the prefrontal cortex of the offspring female mice

Bobula, B.; Kusek, M.; Hess, G.

10.1101/2024.02.26.582031 — neuroscience — Posted on 2024-02-28

301 Alpha-synuclein aggregates trigger anti-viral immune pathways and RNA editing in human astrocytes

D'Sa, K.; Choi, M. L.; Wagen, A. Z.; Seto-Salvia, N.; Kopach, O.; Evans, J. R.; Rodrigues, M.; Lopez-Garcia, P.; Ghareeb, A.; Bayne, J.; Grant-Peters, M.; Garcia-Ruiz, S.; Chen, Z.; Rodriques, S.; Athauda, D.; Gustavsson, E.; Gagliano Taliun, S. A.; Reynolds, R. H.; Young, G.; Strohbuecker, S.; Warner, T.; Rusakov, D. A.; Patani, R.; Bryant, C.; Klenerman, D. A.; Gandhi, S.; Ryten, M.

10.1101/2024.02.26.582055 — neuroscience — Posted on 2024-02-28

302 HB-EGF and EGF infusion following CNS demyelination mitigates age-related decline in regeneration of oligodendrocytes from neural precursor cells originating in the ventricular-subventricular zone

Moradi, K.; Mitew, S.; Xing, Y. L.; Merson, T. D.

10.1101/2024.02.26.582092 — neuroscience — Posted on 2024-02-28

303 The choice-wide behavioral association study: data-driven identification of interpretable behavioral components

Kastner, D. B.; Williams, G.; Holobetz, C.; Romano, J. P.; Dayan, P.

10.1101/2024.02.26.582115 — neuroscience — Posted on 2024-02-28

304 Cyclase-associated protein 1 (CAP1) represses MRTF-SRF-dependent gene expression in the mouse cerebral cortex

Khudayberdiev, S.; Weiss, K.; Heinze, A.; Colombaretti, D.; Trausch, N.; Linne, U.; Rust, M. B.

10.1101/2024.02.26.582060 — neuroscience — Posted on 2024-02-28

305 Pre-existing visual responses in a projection-defined dopamine population explain individual learning trajectories

Pan Vazquez, A.; Sanchez Araujo, Y.; McMannon, B.; Louka, M.; Bandi, A.; Haetzel, L.; International Brain Laboratory, n.; Pillow, J. W.; Daw, N. D.; Witten, I.

10.1101/2024.02.26.582199 — neuroscience — Posted on 2024-02-28

306 Effects of prenatal maternal immune activation and exposure to circadian disruption during adolescence: exploring the two-hit model of neurodevelopmental disorders

Delorme, T. C.; Arcego, D. M.; Penichet, D.; O'Toole, N.; Huebener, N.; Silveira, P. P.; Srivastava, L. K.; Cermakian, N.

10.1101/2024.02.25.580567 — neuroscience — Posted on 2024-02-28

307 Imaging brain vascular function in Cystic Fibrosis: an MRI study of cerebral blood flow and brain oxygenation

Chandler, H. L.; Germuska, M.; Lancaster, T. M.; Xanthe, C.; O'Leary, C.; Stirk, S.; Murphy, K.; Metzler-baddeley, C.; Wise, R. G.; Duckers, J.

10.1101/2024.02.25.581905 — neuroscience — Posted on 2024-02-28

308 Chemically induced senescence prompts functional changes in human microglia-like cells

Armanville, S.; Tocco, C.; Haj Mohamad, Z.; Clarke, D.; Robitaille, R.; Drouin-Ouellet, J.

10.1101/2024.02.27.582168 — neuroscience — Posted on 2024-02-28

309 Inhibition of Protein Synthesis Attenuates Formation of Traumatic Memory and Normalizes Fear-induced c-Fos Expression in a Mouse Model of Posttraumatic Stress Disorder

Zamorina, T. A.; Ivashkina, O. I.; Toropova, K. A.; Anokhin, K. V.

10.1101/2024.02.25.581923 — neuroscience — Posted on 2024-02-28

310 Neural Manifold Capacity Captures Representation Geometry, Correlations, and Task-Efficiency Across Species and Behaviors

Chou, C.-N.; Arend, L.; Wakhloo, A. J.; Kim, R.; Slatton, W.; Chung, S.

10.1101/2024.02.26.582157 — neuroscience — Posted on 2024-02-28

311 Intracellular Lactate Dynamics Reveal the Metabolic Diversity of Drosophila Glutamatergic Neurons

Price, M. S.; Moore, T. I.; Venkatachalam, K.

10.1101/2024.02.26.582095 — neuroscience — Posted on 2024-02-28

312 Opposing Motor Memories in the Direct and Indirect Pathways of the Basal Ganglia

Wen, K.; Shi, Z.; Yu, P.; Mo, L.; Sullere, S.; Yang, V.; Westneat, N.; Beeler, J. A.; McGehee, D. S.; Doiron, B.; Zhuang, X.

10.1101/2024.02.26.582159 — neuroscience — Posted on 2024-02-28

313 NF-kB/NLRP3 Translational Inhibition by Nanoligomer Therapy Mitigates Ethanol and Advanced Age-Related Neuroinflammation

Anton, P. E.; Nagpal, P.; Moreno, J.; Busquet, N.; Burchill, M. A.; Chatterjee, A.; Mesches, M.; Kovacs, E. J.; McCullough, R. L.

10.1101/2024.02.26.582114 — neuroscience — Posted on 2024-02-28

314 Evoked Resonant Neural Activity Long-Term Dynamics can be Reproduced by a Computational Model with Vesicle Depletion

Sermon, J. J.; Wiest, C.; Tan, H.; Denison, T.; Duchet, B.

10.1101/2024.02.25.582012 — neuroscience — Posted on 2024-02-28

315 Mechanosensory cephalic bristles mediate rapid flight initiation in endothermic hawkmoths

Manjunath, M.; Mukunda, C. L.; Sane, S. P.

10.1101/2024.02.28.582474 — neuroscience — Posted on 2024-02-28

316 Distal tuft dendrites shape and maintain new place fields

O'Hare, J. K.; Wang, J.; Shala, M. D.; Polleux, F.; Losonczy, A.

10.1101/2024.02.26.582144 — neuroscience — Posted on 2024-02-28

317 Long-access heroin self-administration induces region specific reduction of grey matter volume and microglia reactivity in the rat.

Cannella, N.; Tambalo, S.; Lunerti, V.; Scuppa, G.; de Vivo, L.; Abdulmalek, S.; Kinen, A.; Mackle, J.; Kuhn, B.; Solberg-Woods, L. N.; Chung, D.; Kalivas, P.; Soverchia, L.; Ubaldi, M.; Hardiman, G.; Bifone, A.; Ciccocioppo, R.

10.1101/2024.02.26.582024 — neuroscience — Posted on 2024-02-28

318 Corticosterone in very young seabird chicks (Rissa tridactyla) is sensitive to environmental variability and responds rapidly and robustly to external challenges

Benowitz-Fredericks, Z. M.; Will, A. P.; Pete, S. N.; Whelan, S.; Kitaysky, A. S.

10.1101/2024.02.25.581949 — physiology — Posted on 2024-02-28

319 A Randomized, Controlled Clinical Trial Demonstrates Improved Cognitive Function in Senior Dogs Supplemented with a Senolytic and NAD+ Precursor Combination.

Simon, K. E.; Russell, K.; Mondino, A.; Yang, C.-C.; Case, B. C.; Anderson, Z.; Whitley, C.; Griffith, E.; Gruen, M. E.; Olby, N. J.

10.1101/2024.02.26.581616 — animal behavior and cognition — Posted on 2024-02-28

320 Expanding the BonnMu sequence-indexed repository of transposon induced maize (Zea mays L.) mutations in dent and flint germplasm

Win, Y. N.; Stöcker, T.; Du, X.; Brox, A.; Pitz, M.; Klaus, A.; Schoof, H.; Hochholdinger, F.; Marcon, C.

10.1101/2024.02.24.581857 — genomics — Posted on 2024-02-28

321 Long-Term Quarantine is Associated with High Cortisol and Low DNA Methylation in New World monkeys

Seenayah, S.; Sanchez Perea, N.; Paredes, U.

10.1101/2024.02.26.582046 — animal behavior and cognition — Posted on 2024-02-28

322 ScISOr-ATAC reveals convergent and divergent splicing and chromatin specificities between matched cell types across cortical regions, evolution, and in Alzheimer's disease.

Hu, W.; Foord, C.; Hsu, J.; Fan, L.; Corley, M. J.; Bhatia, T. N.; Xu, S.; Belchikov, N.; He, Y.; Pang, A. P.; Lanjewar, S. N.; Jarroux, J.; Joglekar, A.; Milner, T. A.; Ndhlovu, L.; Zhang, J.; Butelman, E.; Sloan, S. A.; Lee, V. M.; Gan, L.; Tilgner, H. U.

10.1101/2024.02.24.581897 — genomics — Posted on 2024-02-28

323 Altruistic disease signalling in ant colonies

Dawson, E. H.; Kampleitner, N.; Robb, J.; Strahodinsky, F.; Grasse, A. V.; Cremer, S.

10.1101/2024.02.27.582277 — animal behavior and cognition — Posted on 2024-02-28

324 Individual corticosterone response to intermittent swim stress predicts a shift in economic demand for ethanol from pre-stress to post-stress in male rats

Robison, C. L.; Madore, V.; Cova, N.; Drugan, R. C.; Charntikov, S.

10.1101/2024.02.26.582066 — animal behavior and cognition — Posted on 2024-02-28

325 Multi-ancestry tandem repeat association study of hair color using exome-wide sequencing

Fazzari, V.; Moo-Choy, A.; Panoyan, M. A.; Abbatangelo, C. L.; Polimanti, R.; Novroski, N. M.; Wendt, F. R.

10.1101/2024.02.24.581865 — genomics — Posted on 2024-02-28

326 ILLUSORY LIGHT DRIVES PUPIL RESPONSES IN PRIMATES

Durand, J.-B.; Marchand, S.; Nasres, I.; Laeng, B.; De Castro, V.

10.1101/2024.02.27.582033 — animal behavior and cognition — Posted on 2024-02-28

327 Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

Soltys, V.; Peters, M.; Su, D.; Kucka, M.; Chan, Y. F.

10.1101/2024.02.26.581705 — genomics — Posted on 2024-02-28

328 Whole genome assembly of the Little Millet (Panicum sumatrense) genome: A climate resilient crop species

Das, R. R.; Kumar, A.; Baghel, D. S.; Mahato, A. K.; Dey, N.; Mukherjee, P. K.; Pradhan, S.

10.1101/2024.02.26.582036 — genomics — Posted on 2024-02-28

329 Traits related to pollination and mating result in diverse reproductive strategies in angiosperms

Helmstetter, A. J.; Mendez, M.; Schonenberger, J.; Burgarella, C.; Anderson, B.; Balthazar, M. v.; Billiard, S.; Boer, H. d.; Cros, J.; Delecroix, P.-A.; Dufay, M.; Pannell, J.; Savova Bianchi, D.; Schoen, D.; Vallejo-Marin, M.; Zenil-Ferguson, R.; Sauquet, H.; Glemin, S.; Kafer, J.

10.1101/2024.02.26.582019 — evolutionary biology — Posted on 2024-02-28

330 Ontogenetic variation in the marine foraging of Atlantic salmon functionally links genomic diversity with a major life history polymorphism

Aykanat, T.; Jacobsen, J. A.; Hindar, K.

10.1101/2024.02.26.581711 — ecology — Posted on 2024-02-28

331 Differential proliferation regulates multi-tissue morphogenesis during embryonic axial extension: Integrating viscous modeling and experimental approaches.

Romanos, M.; Salisbury, T.; Stephan, S.; Lansford, R.; Degond, P.; Trescases, A.; Benazeraf, B.

10.1101/2024.02.26.581143 — developmental biology — Posted on 2024-02-28

332 Cerebellar granule cell migration and folia development requires Mllt11/Af1q/Tcf7c

Blommers, M.; Stanton-Turcotte, D.; Witt, E. A.; Heidari, M.; Iulianella, A.

10.1101/2023.09.12.557458 — developmental biology — Posted on 2024-02-28

333 STRESS GRANULE-RELATED GENES DURING EMBRYOGENESIS OF AN INVERTEBRATE CHORDATE

Drago, L.; Pennati, A.; Rothbaecher, U.; Ashita, R.; Hashimoto, S.; Saito, R.; Fujiwara, S.; Ballarin, L.

10.1101/2024.02.26.582042 — developmental biology — Posted on 2024-02-28

334 Identification of teleost tnnc1a enhancers for specific pan-cardiac transcription

Bai, J.; Wei, X.

10.1101/2024.02.26.582099 — developmental biology — Posted on 2024-02-28

335 Villification of the intestinal epithelium is driven by Foxl1

Zhu, G.; Lahori, D.; Schug, J.; Kaestner, K.

10.1101/2024.02.27.582300 — developmental biology — Posted on 2024-02-28

336 A quantitative model for in vivo stem cell decisions in planarians

Frankovits, T.; Cherian, P. V.; Yesharim, Y.; Dobler, S.; Wurtzel, O.

10.1101/2024.02.26.582030 — developmental biology — Posted on 2024-02-28

337 CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling

Eom, D. S.; Bowman, R. L.; Kim, J.

10.1101/2024.02.27.582398 — developmental biology — Posted on 2024-02-28

338 SUMO-mediated regulation of a H3K4me3 reader controls germline development in C. elegans

Carvalho, C. A.; Bening Abu-Shach, U.; Raju, A.; Vershinin, Z.; Levy, D.; Boxem, M.; Broday, L.

10.1101/2024.02.27.582283 — cell biology — Posted on 2024-02-28

339 Nir1-LNS2 is a novel phosphatidic acid biosensor that reveals mechanisms of lipid production

Weckerly, C. C.; Rahn, T. A.; Ehrlich, M.; Wills, R. C.; Pemberton, J. G.; Airola, M. V.; Hammond, G. R.

10.1101/2024.02.28.582557 — cell biology — Posted on 2024-02-28

340 O-GlcNAcylation of the intellectual disability protein DDX3X exerts proteostatic cell cycle control

van Aalten, D. M. F.; Mitchell, C. W.; Yuan, H.; Authier, F.; Sonderstrup-Jensen, M.; Ferenbach, A. T.; d'Alessio, A. M.

10.1101/2024.02.28.582457 — cell biology — Posted on 2024-02-28

341 Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

Schwenzer, N.; Tsukanov, R.; Kohl, T.; Basak, S.; Seibertz, F.; Voigt, N.; Enderlein, J.; Lehnart, S. E.

10.1101/2024.02.26.582084 — cell biology — Posted on 2024-02-28

342 Extracellular matrix dependent regulation of Septin 7 in focal adhesions promotes mechanosensing and response in fibroblasts.

Sturgess, W.; Packirisamy, S.; Geneidy, R.; Swaminathan, V. S.

10.1101/2024.02.27.582035 — cell biology — Posted on 2024-02-28

343 A novel interface for cortical columnar neuromodulation with multi-point infrared neural stimulation

Tian, F.; Zhang, Y.; Schriver, K. E.; Hu, J.; Roe, A. W.

10.1101/2024.02.25.581906 — neuroscience — Posted on 2024-02-28

344 Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury

Karam, J.; Ashfaq, N.; Benitez, C.; Partida, E.; Morales, V.; Hernandez, M.; Yokoyama, J.; Anderson, A. J.; Cummings, B. J.

10.1101/2024.02.26.582018 — neuroscience — Posted on 2024-02-28

345 A 2D Gabor-wavelet baseline model out-performs a 3D surface model in scene-responsive cortex

Shafer-Skelton, A.; Brady, T. F.; Serences, J. T.

10.1101/2024.02.26.582184 — neuroscience — Posted on 2024-02-28

346 CryoVesNet: A Dedicated Framework for Synaptic Vesicle Segmentation in Cryo Electron Tomograms

Khosrozadeh, A.; Seeger, R.; Witz, G.; Radecke, J.; Sorensen, J. B.; Zuber, B.

10.1101/2024.02.26.582080 — neuroscience — Posted on 2024-02-28

347 The intracellular Ca2+ sensitivity of transmitter release from neocortical boutons

Bornschein, G.; Brachtendorf, S.; Eshra, A.; Kraft, R.; Eilers, J.; Hallermann, S.; Schmidt, H.

10.1101/2024.02.26.582057 — neuroscience — Posted on 2024-02-28

348 AI Derived Therapeutic Development for the Treatment of Opioid Use Disorder

Lallai, V.; Martin, A. C.; Fowler, J. P.; Bautista, M.; Mogul, A. S.; Cheepluesak, J. E.; Mirzaei, S.; Jenkins, I.; Lakey, J. R.; Tinder, R.; Fowler, C. D.

10.1101/2024.02.26.579391 — neuroscience — Posted on 2024-02-28

349 Controlling the human connectome with spatially diffuse input signals

Betzel, R. F.; Puxeddu, M. G.; Seguin, C.; Bazinet, V.; Luppi, A.; Podschun, A.; Singleton, S. P.; Faskowitz, J.; Parakkattu, V.; Misic, B.; Markett, S.; Kuceyeski, A.; Parkes, L.

10.1101/2024.02.27.581006 — neuroscience — Posted on 2024-02-28

350 Decoding the spatiotemporal dynamic neural representation of repetitive facial expression imitation

Liu, Q.; Zhou, X.; Zhu, S.; Liu, C.; Yang, Y.; Lan, C.; Song, X.; Becker, B.; Kendrick, K. M.; Zhao, W.

10.1101/2024.02.26.582020 — neuroscience — Posted on 2024-02-28

351 Adoptive transfer of mitochondrial antigen-specific CD8+ T-cells in mice causes parkinsonism and compromises the dopamine system

Elemeery, M. N.; Tchung, A.; Boulet, S.; Mukherjee, S.; Giguere, N.; Daudelin, J.-F.; Hetu-Arbour, R.; Matheoud, D.; STRATTON, J. A.; Labrecque, N.; Trudeau, L.-E.

10.1101/2024.02.26.582098 — neuroscience — Posted on 2024-02-28

352 Stimulation mapping and whole-brain modeling reveal gradients of excitability and recurrence in cortical networks

Momi, D.; Wang, Z.; Parmigiani, S.; Mikulan, E.; Bastiaens, S.; Oveisi, M.; Kadak, K.; Gaglioti, G.; Waters, A.; Hill, S.; Pigorini, A.; Keller, C.; Griffiths, J. D.

10.1101/2024.02.26.581277 — neuroscience — Posted on 2024-02-28

353 Sample preparation methods for volume electron microscopy in mollusc Berghia stephanieae

Drescher, B.; Sant, H. H.; Schalek, R. L.; Lichtman, J. W.; Katz, P. S.

10.1101/2024.02.25.581936 — neuroscience — Posted on 2024-02-28

354 The recovery of parabolic avalanches in spatially subsampled neuronal networks at criticality

Srinivasan, K.; Ribeiro, T. L.; Kells, P.; Plenz, D.

10.1101/2024.02.26.582056 — neuroscience — Posted on 2024-02-28

355 Emo-FilM: A multimodal dataset for affective neuroscience using naturalistic stimuli

Morgenroth, E.; Moia, S.; Vilaclara, L.; Fournier, R.; Muszynski, M.; Ploumitsakou, M.; Almato-Bellavista, M.; Vuilleumier, P.; Van de Ville, D.

10.1101/2024.02.26.582043 — neuroscience — Posted on 2024-02-28

356 Inferring Neural Communication Dynamics from Field Potentials Using Graph Diffusion Autoregression

Schwock, F.; Bloch, J.; Khateeb, K.; Zhou, J.; Atlas, L.; Yazdan-Shahmorad, A.

10.1101/2024.02.26.582177 — neuroscience — Posted on 2024-02-28

357 Human stem cell derived neurons and astrocytes to detect auto-reactive IgG in neurological diseases

Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.

10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-02-28

358 Comparative study of enriched dopaminergic neurons from siblings with Gaucher disease discordant for parkinsonism

Hertz, E.; Perez, G.; Hao, Y.; Rytel, K.; Ma, C.; Kirby, M.; Anderson, S.; Wincovitch, S.; Andersh, K.; Ahfeldt, T.; Blanchard, J.; Qi, Y. A.; Lopez, G.; Tayebi, N.; Sidransky, E.; Chen, Y.

10.1101/2024.02.25.581985 — neuroscience — Posted on 2024-02-28

359 Steeper or Faster? Impacts of Similar-intensity Running Conditions on Heart Rate Variability

ElDash, V. M.; ElDash, I. M. C. A.; Marques, F. S.; Natali, J. E. S.; Chaui-Berlinck, J. G.

10.1101/2024.02.23.581819 — physiology — Posted on 2024-02-28

360 Short periods of decreased water flow may modulate long-term ocean acidification in reef-building corals

Martins, C. P. P.; Simancas-Giraldo, S. M.; Schubert, P.; Wall, M.; Wild, C.; Wilke, T.; Ziegler, M.

10.1101/2024.02.23.581783 — physiology — Posted on 2024-02-28

361 CTAT-LR-fusion: accurate fusion transcript identification from long and short read isoform sequencing at bulk or single cell resolution

Qin, Q.; Popic, V.; Yu, H.; White, E.; Khorgade, A.; Shin, A.; Wienand, K.; Dondi, A.; Beerenwinkel, N.; Vazquez, F.; AlKhafaji, A. M.; Haas, B. J.

10.1101/2024.02.24.581862 — cancer biology — Posted on 2024-02-28

362 Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells

Kasap, C.; Izgutdina, A.; Patino-Escobar, B.; Kang, A.; Chilakapati, N.; Akagi, N.; Johnson, H.; Rashid, T.; Werner, J.; Barpanda, A.; Geng, H.; Lin, Y.-H. T.; Rampersaud, S.; Gil-Alos, D.; Sobh, A.; Dupere-Richer, D.; Wicaksono, G.; Kelii, K. M. K.; Dalal, R.; Ramos, E.; Vijayanarayanan, A.; Salangsang, F.; Phojanakong, P.; Camara Serrano, J. A.; Zakraoui, O.; Tariq, I.; Steri, V.; Shanmugam, M.; Boise, L. H.; Kortemme, T.; Stieglitz, E.; Licht, J. D.; Karlon, W. J.; Barwick, B. G.; Wiita, A.

10.1101/2024.02.24.581875 — cancer biology — Posted on 2024-02-28

363 Oncogenic GNAS drives a gastric pylorus program in intraductal papillary mucinous neoplasms of the pancreas

Trinh, V. Q.-H.; Ankenbauer, K. E.; Liu, J.; Batardiere, M.; Maurer, H. C.; Copeland, C.; Wong, J.; Ben-Levy, O.; Torbit, S. M.; Jarvis, B.; Revetta, F.; Ivanov, S.; Jyotsana, N.; Makino, Y.; Ruelas, A. M.; Means, A. L.; Maitra, A.; Tan, M. C. B.; DelGiorno, K. E.

10.1101/2024.02.25.581948 — cancer biology — Posted on 2024-02-28

364 Rheological and Lipid Characterization of Minipig and Human Skin Tissue: A Comparative Study Across Different Locations and Depths

Mitra, H.; Nonamaker, E. M.; Corder, R. D.; Solorio, L.; Ardekani, A. M.

10.1101/2024.02.25.581953 — biophysics — Posted on 2024-02-28

365 CTFFIND5 provides improved insight into quality, tilt and thickness of TEM samples

Elferich, J.; Kong, L.; Zottig, X.; Grigorieff, N.

10.1101/2024.02.26.582023 — biophysics — Posted on 2024-02-28

366 Small molecules targeting the structural dynamics of AR-V7 partially disordered protein using deep learning and physics based models

Karatzas, P.; Brotzakis, Z. F.; Sarimveis, H.

10.1101/2024.02.23.581804 — bioinformatics — Posted on 2024-02-28

367 Comparative Analysis of Gene Expression Analysis Methods for RNA In Situ Hybridization Images

Ariotta, V.; Azzalini, E.; Canzonieri, V.; Hautaniemi, S.; BONIN, S.

10.1101/2024.02.25.581931 — bioinformatics — Posted on 2024-02-28

368 Quantification of metabolic activity from isotope tracing data using automated methodology

Liu, S.; Liu, X.; Locasale, J.

10.1101/2024.02.25.581907 — bioinformatics — Posted on 2024-02-28

369 Modeling cancer dependency with deep graph models

Wang, P.; Fu, H.; Zhao, B.

10.1101/2024.02.26.582022 — bioinformatics — Posted on 2024-02-28

370 Bioactive coatings on 3D printed scaffolds for bone regeneration: Use of Laponite(R) to deliver BMP-2 in an ovine femoral condyle defect model

Marshall, K. M.; McLaren, J. S.; Wojciechowski, J. P.; Callens, S. J. P.; Echalier, C.; Kanczler, J. M.; Rose, F. R. A. J.; Stevens, M. M.; Dawson, J. I.; Oreffo, R. O. C.

10.1101/2024.02.25.581921 — bioengineering — Posted on 2024-02-28

371 Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer cells

Buglakova, E.; Ekelöf, M.; Schwaiger-Haber, M.; Schlicker, L.; Molenaar, M. R.; Mohammed, S.; Stuart, L.; Eisenbarth, A.; Hilsenstein, V.; Patti, G.; Schulze, A.; Snaebjornsson, M.; Alexandrov, T.

10.1101/2023.08.18.553810 — biochemistry — Posted on 2024-02-28

372 Identifying HRV and EEG correlates of well-being using ultra-short, portable, and low-cost measurements

Cannard, C.; Delorme, A.; Wahbeh, H.

10.1101/2024.02.23.581823 — physiology — Posted on 2024-02-28

373 GM-CSF and IL-3 expression increases immune engraftment and tumor infiltration in a humanized patient-derived xenograft model of hepatocellular carcinoma

Weinfurtner, K.; Tischfield, D.; McClung, G.; Crainic, J.; Jiao, J.; Li, W.; Kaplan, D. E.; Gade, T. P.

10.1101/2023.10.05.561117 — cancer biology — Posted on 2024-02-28

374 Neuronal and behavioral responses to naturalistic texture images in macaque monkeys

Ziemba, C. M.; Goris, R. L. T.; Stine, G. M.; Perez, R. K.; Simoncelli, E. P.; Movshon, J. A.

10.1101/2024.02.22.581645 — neuroscience — Posted on 2024-02-28

375 Metabolic control of adaptive β-cell proliferation by the protein deacetylase SIRT2

Wortham, M.; Ramms, B.; Zeng, C.; Benthuysen, J. R.; Sai, S.; Pollow, D. P.; Liu, F.; Schlichting, M.; Harrington, A. R.; Liu, B.; Prakash, T. P.; Pirie, E. C.; Zhu, H.; Baghdasarian, S.; Auwerx, J.; Shirihai, O. S.; Sander, M.

10.1101/2024.02.24.581864 — physiology — Posted on 2024-02-28

376 Genetic diversity and connectivity of the invasive gastropod, Callinina georgiana (Caenogastropoda: Viviparidae) across a fragmented riverscape: a mitonuclear perspective.

Abeyrathna, W.; Davinack, A. A.

10.1101/2024.02.24.581858 — ecology — Posted on 2024-02-28

377 Schlafen-11 and -9 are innate immune sensors for intracellular single-stranded DNA

Liu, D.; Zhang, P.; Hu, X.; Li, Z.; Liu, S.; Jin, Y.; Wang, J.; Chen, H.; Hao, D.; Zhao, X.; Liu, L.; Liu, Q.

10.1101/2024.02.24.581893 — immunology — Posted on 2024-02-28

378 A VHL-1/HIF-1/SQRD1/COL-88 axis links extracellular matrix formation with longevity in Caenorhabditis elegans

Salgueiro, W.; Esmaillie, R.; Bohl, K.; Statzer, C.; Bharill, P.; Bargfrede, S.; Chokkalingam, M.; Neutzer, M.; Ignarski, M.; Benzing, T.; Beyer, A.; Schermer, B.; Ewald, C.; Fabretti, F.; Müller, R.-U.

10.1101/2024.02.22.581513 — genetics — Posted on 2024-02-28

379 The Ubiquitin Ligase RBX2/SAG Regulates Mitochondrial Ubiquitination and Mitophagy

Wang, W.; Li, E.; Zou, J.; Qu, C.; Ayala, J.; Wen, Y.; Islam, M. S.; Weintraub, N. L.; Fulton, D. J.; Liang, Q.; Zhou, J.; Liu, J.; Li, J.; Sun, Y.; Su, H.

10.1101/2024.02.24.581168 — pathology — Posted on 2024-02-28

380 Enhanced microbiota profiling in patients with quiescent Crohn's disease through comparison with paired healthy first-degree relatives using fecal metagenomics and metabolomics

Chen, W.; Li, Y.; Wang, W.; Gao, S.; Wu, D.; Jiao, N.; Xu, T.; Zhi, M.; Zhu, L.; Zhu, R.

10.1101/2024.02.24.581863 — pathology — Posted on 2024-02-28

381 cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning

Araki, D.; Hong, S.; Linde, N.; Fisk, B.; Redekar, N.; Salisbury-Ruf, C.; Krouse, A.; Engels, T.; Golomb, J.; Dagur, P.; Magnani, D. M.; Wang, Z.; Larochelle, A.

10.1101/2024.02.24.581887 — cell biology — Posted on 2024-02-28

382 Dietary bacteria controls C. elegans lipid metabolism through pathways converging at phosphatidylcholine

Han, H.; Nien, S.-F.; Jiang, H.-S.; Wu, J.-C.; Chiang, C.-Y.; Li, M.-T.; Huang, L.-J.; Chiang, S.; Lin, L.-C.; Chuang, Y.-T.; Lin, Y.-H.; Wang, C.-W.; Wu, Y.-C.

10.1101/2024.02.24.581900 — cell biology — Posted on 2024-02-28

383 Male and female variability in response to chronic stress and morphine in C57BL/6J, DBA/2J, and their BXD progeny

Morel, C.; Parise, L. F.; Van der Zee, Y.; Issler, O.; Cai, M.; Browne, C. J.; Blando, A.; LeClair, K. B.; Hayes, S.; Williams, R. W.; Mulligan, M. K.; Nestler, E. J.; Russo, S.; Han, M.-H.

10.1101/2024.02.23.581795 — neuroscience — Posted on 2024-02-28

384 Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in C. elegans

Raices, M.; Balmir, F.; Silva, N.; Li, W.; Grundy, M. K.; Hoffman, D. K.; Altendorfer, E.; Camacho, C. J.; Bernstein, K.; Colaiacovo, M. P.; Yanowitz, J.

10.1101/2024.02.23.581796 — developmental biology — Posted on 2024-02-28

385 Kir6.2-KATP channels alter glycolytic flux to modulate cortical activity, arousal, and sleep-wake homeostasis

Constantino, N. J.; Carroll, C. M.; Williams, H. C.; Yuede, C. M.; Sheehan, P. W.; Snipes, J. A.; Musiek, E. S.; Johnson, L. A.; Macauley, S. L.

10.1101/2024.02.23.581817 — neuroscience — Posted on 2024-02-28

386 Wake EEG oscillation dynamics reflect both sleep need and brain maturation across childhood and adolescence

Snipes, S.; Krugliakova, E.; Jaramillo, V.; Volk, C.; Furrer, M.; Studler, M.; LeBourgeois, M.; Kurth, S.; Jenni, O. G.; Huber, R.

10.1101/2024.02.24.581878 — neuroscience — Posted on 2024-02-28

387 Multimodal histopathologic models stratify hormone receptor-positive early breast cancer

Boehm, K. M.; El Nahhas, O. S. M.; Marra, A.; Selenica, P.; Wen, H. Y.; Weigelt, B.; Paul, E. D.; Cekan, P.; Erber, R.; Loeffler, C. M. L.; Guerini-Rocco, E.; Fusco, N.; Frascarelli, C.; Mane, E.; Munzone, E.; Dellapasqua, S.; Zagami, P.; Curigliano, G.; Razavi, P.; Reis-Filho, J. S.; Pareja, F.; Chandarlapaty, S.; Shah, S. P.; Kather, J. N.

10.1101/2024.02.23.581806 — pathology — Posted on 2024-02-28

388 Efficient and reproducible generation of human iPSC-derived cardiomyocytes using a stirred bioreactor

Prondzynski, M.; Bortolin, R. H.; Berkson, P.; Trembley, M. A.; Shani, K.; Sweat, M. E.; Mayourian, J.; Anyanwu, N. J.; Cordoves, A. M.; Tharani, Y.; Cotton, J.; Milosh, J. B.; Walker, D.; Zhang, Y.; Lu, F.; Liu, X.; Parker, K. K.; Bezzerides, V. J.; Pu, W. T.

10.1101/2024.02.24.581789 — cell biology — Posted on 2024-02-28

389 A simulated annealing algorithm for randomizing weighted networks

Milisav, F.; Bazinet, V.; Betzel, R.; Misic, B.

10.1101/2024.02.23.581792 — neuroscience — Posted on 2024-02-28

390 A generic noninvasive neuromotor interface for human-computer interaction

Ctrl-labs at Reality Labs, ; Sussillo, D.; Kaifosh, P.; Reardon, T.

10.1101/2024.02.23.581779 — neuroscience — Posted on 2024-02-28

391 Object motion representation in the macaque ventral stream -- a gateway to understanding the brain's intuitive physics engine

Ramezanpour, H.; Ilic, F.; Wildes, R.; Kar, K.

10.1101/2024.02.23.581841 — neuroscience — Posted on 2024-02-28

392 Late-Life Alcohol Exposure Does Not Exacerbate Age-Dependent Reductions in Mouse Spatial Memory and Brain TFEB Activity

Chen, H.; Hinz, K.; Zhang, C.; Rodriguez, Y.; Williams, S. N.; Niu, M.; Ma, X.; Chao, X.; Frazier, A. L.; McCarson, K. E.; Wang, X.; Peng, Z.; Liu, W.; Ni, H.-M.; Zhang, J.; Swerdlow, R. H.; Ding, W.-X.

10.1101/2024.02.23.581774 — animal behavior and cognition — Posted on 2024-02-28

393 Hydroponics: A Novel Approach to Culturing Aphanomyces euteiches

Done, E.

10.1101/2023.10.30.564802 — microbiology — Posted on 2024-02-28

394 Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

Podkowik, M.; Perault, A. I.; Putzel, G.; Pountain, A.; Kim, J.; DuMont, A.; Zwack, E.; Ulrich, R. J.; Karagounis, T. K.; Zhou, C.; Haag, A. F.; Shenderovich, J.; Wasserman, G. A.; Kwon, J.; Chen, J.; Richardson, A. R.; Weiser, J. N.; Nowosad, C. R.; Lun, D. S.; Zhao, X.; Parker, D.; Pironti, A.; Drlica, K. N.; Yanai, I.; Torres, V. J.; Shopsin, B.

10.1101/2023.06.08.544038 — microbiology — Posted on 2024-02-28

395 Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity

Otero, C. E.; Petkova, S.; Ebermann, M.; Taher, H.; John, N.; Hoffmann, K.; Davalos, A.; Mostrom, M. J.; Gilbride, R. M.; Papen, C.; Barber-Axthelm, A.; Scheef, E. A.; Barfield, R.; Sprehe, L. M.; Kendall, S.; Manuel, T. D.; Vande Burgt, N.; Chan, C.; Streblow, D. N.; Hansen, S. G.; Denton, M.; Streblow, Z.; Kaur, A.; Permar, S. R.; Frueh, K.; Hengel, H.; Malouli, D.; Kolb, P.

10.1101/2024.02.27.582371 — microbiology — Posted on 2024-02-28

396 Mating-compatibility genes employed as diagnostic markers to identify novel incursions of the myrtle rust pathogen Austropuccinia psidii

Feng, J.; Bird, A.; Luo, Z.; Tam, R.; Shepherd, L.; Murphy, L.; Singh, L.; Graetz, A.; Moeller, M.; Amorim, L.; Massola Junior, N. S.; Prodhan, M. A.; Shuey, L.; Beattie, D.; Gonzalez, A. T.; Tobias, P. A.; Padovan, A.; Kimber, R.; McTaggart, A.; Kehoe, M.; Schwessinger, B.; Boufleur, T. R.

10.1101/2024.02.19.580897 — plant biology — Posted on 2024-02-28

397 MutationExplorer - a webserver for mutation of proteins and 3D visualization of energetic impacts

Philipp, M.; Moth, C. W.; Ristic, N.; Tiemann, J. K. S.; Seufert, F.; Panfilova, A.; Meiler, J.; Hildebrand, P.-W.; Stein, A.; Wiegreffe, D.; Staritzbichler, R.

10.1101/2023.03.23.533926 — bioinformatics — Posted on 2024-02-28

398 Simpler protein domain identification using spectral clustering

Cazals, F.; Herrmann, J.; Sarti, E.

10.1101/2024.02.10.579762 — bioinformatics — Posted on 2024-02-28

399 Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning

Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Bayraktar, O.; Theis, F. J.; Talavera-Lopez, C.; Lotfollahi, M.

10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-02-28

400 Thermal acclimation of stem respiration reduces global carbon burden

Zhang, H.; Wang, H.; Wright, I. J.; Prentice, C.; Harrison, S. P.; Smith, N. G.; Westerband, A.; Rowland, L.; Plavcova, L.; Morris, H.; Reich, P. B.; Jansen, S.; Keenan, T.

10.1101/2024.02.23.581610 — ecology — Posted on 2024-02-28

401 Fifty Years After: The N1 Effect Travels Down to the Brainstem

Strauss, D. J.; Corona-Strauss, F. I.; Mai, A.; Hillyard, S. A.

10.1101/2024.02.23.581747 — neuroscience — Posted on 2024-02-28

402 Biomechanical Costs Influence Decisions Made During Ongoing Actions

Canaveral, C. A.; Lata, W.; Green, A.; Cisek, P.

10.1101/2024.02.26.582113 — neuroscience — Posted on 2024-02-28

403 Visual Image Reconstructed Without Semantics from Human Brain Activity Using Linear Image Decoders and Nonlinear Noise Suppression

Li, Q.

10.1101/2023.09.23.559147 — neuroscience — Posted on 2024-02-28

404 Integrative, Segregative, and Degenerate Harmonics of the Structural Connectome

Sipes, B. S.; Nagarajan, S.; Raj, A.

10.1101/2024.02.23.581784 — neuroscience — Posted on 2024-02-28

405 Neurons underlying aggressive actions that are shared by both males and females in Drosophila

Tao, L.; Ayambem, D.; Barranca, V. J.; Bhandawat, V.

10.1101/2024.02.26.582148 — neuroscience — Posted on 2024-02-28

406 Transcriptomic signature and pro-osteoclastic secreted factors of abnormal bone marrow stromal cells in fibrous dysplasia

Michel, Z.; Raborn, L. N.; Spencer, T.; Pan, K. S.; Martin, D.; Roszko, K. L.; Wang, Y.; Robey, P.; Boyce, A.; Collins, M. T.; de Castro, L. F.

10.1101/2024.02.23.581225 — pathology — Posted on 2024-02-28

407 Mapping chromatin remodelling in glioblastoma identifies epigenetic regulation of key molecular pathways and novel druggable targets.

Vinel, C.; Boot, J.; Jin, W.; Pomella, N.; Mein, C.; Zabet, R.; Marino, S.

10.1101/2024.02.24.581853 — cancer biology — Posted on 2024-02-28

408 A circadian behavioral analysis suite for real-time classification of daily rhythms in complex behaviors

Perry, L. J.; Perez, B. E.; Rays Wahba, L.; Nikhil, K.; Starnes, A. N.; Lenzen, W. C.; Jones, J. R.

10.1101/2024.02.23.581778 — animal behavior and cognition — Posted on 2024-02-28

409 Food-associated calls in disc-winged bats

Chaverri, G.; Page, R. A.

10.1101/2024.02.25.581993 — animal behavior and cognition — Posted on 2024-02-28

410 Nevertheless sex persisted: facultative sex persists despite high costs in a sexually polymorphic aphid parasitoid

Boulton, R. A.

10.1101/2024.02.25.581911 — evolutionary biology — Posted on 2024-02-28

411 Selection of movement rules to simulate species dispersal in a mosaic landscape model

Gold, S.; Croft, S.; Budgey, R.; Aegerter, J. N.

10.1101/2024.02.26.582052 — ecology — Posted on 2024-02-28

412 A half-centre oscillator encodes sleep pressure

Hasenhuetl, P. S.; Sarnataro, R.; Vrontou, E.; Rorsman, H. O.; Talbot, C. B.; Brain, R.; Miesenboeck, G.

10.1101/2024.02.23.581780 — neuroscience — Posted on 2024-02-28

413 A generative model of the connectome with dynamic axon growth

Liu, Y.; Seguin, C.; Betzel, R. F.; Akarca, D.; Di Biase, M. A.; Zalesky, A.

10.1101/2024.02.23.581824 — neuroscience — Posted on 2024-02-28

414 Active filtering of sequences of neural activity by recurrent circuits of sensory cortex

Deveau, C.; Zhou, Z.; LaFosse, P. K.; Deng, Y.; Mirbagheri, S.; Steinmetz, N.; Histed, M. H.

10.1101/2024.02.24.581890 — neuroscience — Posted on 2024-02-28

415 The transcriptional response of cortical neurons to concussion reveals divergent fates after injury

Alkaslasi, M. R.; Lloyd, E. Y. H.; Gable, A. S.; Silberberg, H.; Yarur, H. E.; Tsai, V. S.; Tejeda, H. A.; Le Pichon, C. E.

10.1101/2024.02.26.581939 — neuroscience — Posted on 2024-02-28

416 High sensitivity cameras can lower spatial resolution in high-resolution optical microscopy

Ortkrass, H.; Mueller, M.; Engdahl, A. K.; Holst, G.; Huser, T.

10.1101/2024.02.23.581754 — biophysics — Posted on 2024-02-28

417 A Decade of Progress: Insights of Open Data Practices in Biosciences at the University of Edinburgh

Deeb, H.; Wong, H. Y.; Usman, T.; Kutzer, M. A. M.; Zielinski, T.; Millar, A. J.

10.1101/2024.02.18.580901 — bioinformatics — Posted on 2024-02-28

418 Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

Andolina, C.; Graumans, W.; Guelbeogo, M.; Gemert, G.-J. v.; Ramjith, J.; Harouna, S.; Soumanaba, Z.; Stoter, R.; van de Vegte-Bolmer, M.; Pangos, M.; Sinnis, P.; Collins, K.; Staedke, S.; Tiono, A.; Drakeley, C.; Lanke, K.; Bousema, T.

10.1101/2023.08.03.551751 — microbiology — Posted on 2024-02-28

419 On the mechanical origins of waving, coiling and skewing in Arabidopsis thaliana roots

Porat, A.; Tekinalp, A.; Bhosale, Y.; Gazzola, M.; Meroz, Y.

10.1101/2023.05.17.541081 — plant biology — Posted on 2024-02-28

420 STRING-ing together protein complexes: corpus and methods for extracting physical protein interactions from the biomedical literature

Mehryary, F.; Nastou, K.; Ohta, T.; Jensen, L. J.; Pyysalo, S.

10.1101/2023.12.10.570999 — bioinformatics — Posted on 2024-02-28

421 Extended blood stage sensitivity profiles of Plasmodium vivax to doxycycline and tafenoquine using Plasmodium cynomolgi as a model

Christensen, P.; Cinzah, R.; Suwanarusk, R.; Chua, A. C. Y.; Kaneko, O.; Kyle, D. E.; Aung, H. L.; Matheson, J.; Bifani, P.; Renia, L.; Cook, G. M.; Snounou, G.; Russell, B. M.

10.1101/2024.02.23.581752 — microbiology — Posted on 2024-02-28

422 Stimulated saliva has a distinct composition that influences release of volatiles from wine

Ruan, X.; Chen, Y.; Chauhan, A.; Howell, K.

10.1101/2024.02.25.581677 — microbiology — Posted on 2024-02-28

423 An ancient ecospecies of Helicobacter pylori found in Indigenous populations and animal adapted lineages.

Tourrette, E.; Torres, R. C.; Svensson, S. L.; Matsumoto, T.; Fauzia, K. A.; Alfaray, R. I.; Vilaichone, R.-K.; Tuan, V. P.; HelicobacterGenomicsConsortium, ; Wang, D.; Olsson, L.; Yadegar, A.; Zhou, Z.; Yamaoka, Y.; Thorell, K.; Falush, D.

10.1101/2023.04.28.538659 — microbiology — Posted on 2024-02-28

424 Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers

Gharzeddine, K.; Gonzales Pietro, C.; Malier, M.; Hennot, C.; Grespan, R.; Yamaryo, Y.; Botte, C.; Thomas, F.; Laverriere, M. H.; Girard, E.; Roth, G.; MILLET, A.

10.1101/2024.02.22.581558 — immunology — Posted on 2024-02-28

425 Gradient boosted decision trees reveal nuances of auditory discrimination behaviour

Griffiths, C. S.; Lebert, J. M.; Sollini, J.; Bizley, J. K.

10.1101/2023.06.16.545302 — neuroscience — Posted on 2024-02-28

426 Sensory neuron population expansion enhances odor tracking without sensitizing projection neurons

Takagi, S.; Sancer, G.; Abuin, L.; Stupski, S. D.; Arguello, J. R.; Prieto-Godino, L. L.; Stern, D. L.; Cruchet, S.; Alvarez-Ocana, R.; Wienecke, C. F. R.; van Breugel, F.; Jeanne, J. M.; Auer, T. O.; Benton, R.

10.1101/2023.09.15.556782 — neuroscience — Posted on 2024-02-28

427 In-Vivo and In-Vitro Toxicity Evaluation of 2,3-Dimethylquinoxaline: an Antimicrobial Found in a Traditional Herbal Medicine

Alfadil, A.; Alsamhan, H.; Ali, A.; Alkreathy, H.; Alrabia, M.; fatani, A.; A Ibrahem, K.

10.1101/2024.02.23.581713 — pathology — Posted on 2024-02-28

428 Vocalization Patterns in Laying Hens - An Analysis of Stress-Induced Audio Responses

Neethirajan, S.

10.1101/2023.12.26.573338 — animal behavior and cognition — Posted on 2024-02-28

429 Pupil dilation reflects effortful action invigoration in overcoming aversive Pavlovian biases

Algermissen, J.; den Ouden, H. E. M.

10.1101/2023.12.28.573353 — neuroscience — Posted on 2024-02-28

430 The contribution of Mediterranean connectivity to morphological variability in Iron Age sheep of the Eastern Mediterranean

Harding, S. A.; Hadjikoumis, A.; Vermeersch, S.; Marom, N.

10.1101/2022.12.24.521859 — paleontology — Posted on 2024-02-28

431 Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN

Panei, F. P.; Gkeka, P.; Bonomi, M.

10.1101/2023.08.08.552403 — bioinformatics — Posted on 2024-02-28

432 Context-Aware Amino Acid Embedding Advances Analysis of TCR-Epitope Interactions

Zhang, P.; Bang, S.; Cai, M.; Lee, H.

10.1101/2023.04.12.536635 — bioinformatics — Posted on 2024-02-28

433 Genetic and transcriptomic dissection of nitrate-independent function of Arabidopsis NRT1.1/NPF6.3/CHL1 under high ammonium condition

Hachiya, T.; Makita, N.; Bach, L.; Gojon, A.; Nakagawa, T.; Sakakibara, H.

10.1101/2023.10.17.562629 — plant biology — Posted on 2024-02-28

434 Propionyl-CoA carboxylase subunit B regulates anti-tumor T cells in a pancreatic cancer mouse model

Han, H. V.; Efem, R.; Rosati, B.; Lu, K.; Maimouni, S.; Jiang, Y.-P.; Montoya, V.; Van Der Velden, A.; Zong, W.-X.; Lin, R. Z.

10.1101/2023.07.24.550301 — cancer biology — Posted on 2024-02-28

435 Enhancer landscape of lung neuroendocrine tumors reveals regulatory and developmental signatures with potential theranostic implications

Davis, E.; Avniel-Polak, S.; Abu-Kamel, S.; Antman, I.; Saadoun, T.; Brim, C.; Bel-Ange, A.; Atlan, K.; Tzur, T.; Abu-Akar, F.; Wald, O.; Izhar, U.; Hecht, M.; Grozinsky-Glasberg, S.; Drier, Y.

10.1101/2023.11.17.566871 — cancer biology — Posted on 2024-02-28

436 Active hydraulics and odd elasticity of muscle fibers

Shankar, S.; Mahadevan, L.

10.1101/2022.02.20.481216 — biophysics — Posted on 2024-02-28

437 Cell Fate Simulation Reveals Cancer Cell Features in the Tumor Microenvironment

Sato, S.; Rancourt, A.; Satoh, M. S.

10.1101/508705 — bioinformatics — Posted on 2024-02-28

438 Evaluating batch correction methods for image-based cell profiling

Arevalo, J.; Su, E.; van Dijk, R.; Carpenter, A. E.; Singh, S.

10.1101/2023.09.15.558001 — bioinformatics — Posted on 2024-02-28

439 Overcoming the nutritional immunity by engineering iron scavenging bacteria for cancer therapy

Huang, S.-W.; Lim, S.-K.; Yu, Y.-A.; Pan, Y.-C.; Lien, W.-J.; Mou, C.-Y.; Hu, C.-M. J.; Mou, K. Y.

10.1101/2023.07.25.550605 — bioengineering — Posted on 2024-02-28

440 Cdc13 exhibits dynamic DNA strand exchange in the presence of telomeric DNA

Nickens, D. G.; Feng, Z.; Shen, J.; Gray, S. J.; Simmons, R. H.; Niu, H.; Bochman, M. L.

10.1101/2023.12.04.569902 — biochemistry — Posted on 2024-02-28

441 Differential effects of multiplex and uniplex affiliative relationships on biomarkers of inflammation

Vandeleest, J. J.; Wooddell, L. J.; Nathman, A. C.; Beisner, B. A.; McCowan, B.

10.1101/2022.11.01.514247 — animal behavior and cognition — Posted on 2024-02-28

442 A harmonized public resource of deeply sequenced diverse human genomes

Koenig, Z.; Yohannes, M. T.; Nkambule, L. L.; Zhao, X.; Goodrich, J. K.; Kim, H. A.; Wilson, M. W.; Tiao, G.; Hao, S. P.; Sahakian, N.; Chao, K. R.; Walker, M. A.; Lyu, Y.; gnomAD Project Consortium, ; Rehm, H.; Neale, B.; Talkowski, M. E.; Daly, M. J.; Brand, H.; Karczewski, K.; Atkinson, E. G.; Martin, A.

10.1101/2023.01.23.525248 — genomics — Posted on 2024-02-28

443 Difference in genetic architecture is a key driver in plant-to-plant interaction: case study of height and rust damages in Populus nigra

Tiret, M.; Sanchez, L.; Lascoux, M.

10.1101/2023.06.21.545987 — genetics — Posted on 2024-02-28

444 Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network

Dibyachintan, S.; Dube, A. K.; Bradley, D.; Lemieux, P.; Dionne, U.; Landry, C.

10.1101/2024.02.23.581840 — evolutionary biology — Posted on 2024-02-28

445 The evolution of diverse antimicrobial responses in vancomycin-intermediate Staphylococcus aureus and its therapeutic implications

Crozier, D.; Gray, J. M.; Maltas, J. A.; Bonomo, R. A.; Burke, Z. D. C.; Card, K. J.; Scott, J. G.

10.1101/2023.11.30.569373 — evolutionary biology — Posted on 2024-02-28

446 Cytoneme-mediated intercellular signaling in keratinocytes essential for epidermal remodeling

Wang, Y.; He, Q.; Has, O.; Forouzesh, K.; Eom, D. S.

10.1101/2023.11.08.566303 — developmental biology — Posted on 2024-02-28

447 Proinflammatory Cytokines Suppress Nonsense-Mediated RNA Decay to Impair Regulated Transcript Isoform Processing in Pancreatic β-Cells

Ghiasi, S.; Marchetti, P.; Piemonti, L.; Nielsen, J.; Porse, B.; Mandrup-Poulsen, T.; Rutter, G. A.

10.1101/2023.12.20.572623 — cell biology — Posted on 2024-02-28

448 The Arthropoda-specific Tramtrack group BTB protein domains use previously unknown interface to form hexamers

Bonchuk, A.; Balagurov, K.; Baradaran, R.; Boyko, K.; Sluchanko, N. N.; Khrustaleva, A.; Burtseva, A.; Arkova, O.; Khalisova, K.; Popov, V.; Naschberger, A.; Georgiev, P.

10.1101/2022.09.01.506177 — molecular biology — Posted on 2024-02-28

449 Characterisation of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina

Kumar, S.; Hsiao, Y.-W.; Wong, V. H. Y.; Aubin, D.; Wang, J.-H.; Lisowski, L.; Rakoczy, E. P.; Li, F.; Alarcon-Martinez, L.; Gonzalez Cordero, A.; Bui, B. V.; Liu, G.-S.

10.1101/2024.02.10.579778 — molecular biology — Posted on 2024-02-28

450 Choline degradation in Paracoccus denitrificans: identification of sources of formaldehyde

Parekh, T.; Tsai, M.; Spiro, S.

10.1101/2023.12.12.567942 — microbiology — Posted on 2024-02-28

451 Distinct microcolony morphologies promote flow-dependent bacterial colonization

Hallinen, K. M.; Bodine, S. P.; Stone, H. A.; Muir, T. W.; Wingreen, N. S.; Gitai, Z.

10.1101/2023.11.22.568348 — microbiology — Posted on 2024-02-28

452 Cell class-specific electric field entrainment of neural activity

Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.

10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-02-28

453 Genetic mapping identifies Homer1 as a developmental modifier of attention

Gershon, Z. Z.; Bonito-Oliva, A.; Kanke, M.; Terceros, A.; Rankin, G.; Fak, J.; Harada, Y.; Iannone, A. F.; Gebrehemedin, M.; Fabella, B.; De Marco Garcia, N.; Sethupathy, P.; Rajasethupathy, P.

10.1101/2023.03.17.533136 — neuroscience — Posted on 2024-02-28

454 Cross-species alignment along the chronological axis reveals evolutionary effect on structural development of human brain

Li, Y.; Sun, Q.; Zhu, S.; Chu, C.; Wang, J.

10.1101/2024.02.27.582251 — neuroscience — Posted on 2024-02-28

455 Working memory representations are spatially transferred in cortex during mental manipulations

Chernik, C.; van den Berg, R.; Lundqvist, M.

10.1101/2024.02.27.582343 — neuroscience — Posted on 2024-02-28

456 Neural Trajectories of Conceptually Related Events

Schafer, M.; Kamilar-Britt, P.; Sahani, V.; Bachi, K.; Schiller, D.

10.1101/2023.12.04.569670 — neuroscience — Posted on 2024-02-28

457 Mitochondrial complex I deficiency stratifies idiopathic Parkinson's disease

Flones, I.; Toker, L.; Sandnes, D. A.; Castelli, M.; Mostafavi, S.; Lura, N.; Shadad, O.; Fernandez-Vizarra, E.; Painous, C.; Perez-Soriano, A.; Compta, Y.; Molina-Porcel, L.; Alves, G.; Tysnes, O.-B.; Dolle, C.; Nido, G. S.; Tzoulis, C.

10.1101/2023.09.22.558615 — neuroscience — Posted on 2024-02-28

458 Exploring Decision-making Processes: The Impact of Acute High-Intensity Aerobic Exercise

Davranche, K.; Giraud, D.; Hays, A.; Gajdos, T.

10.1101/2023.02.14.528466 — neuroscience — Posted on 2024-02-28

459 The Time-Course of Food Representation in the Human Brain

Moerel, D.; Psihoyos, J.; Carlson, T. A.

10.1101/2023.06.06.543985 — neuroscience — Posted on 2024-02-28

460 Timing of methamphetamine exposure during adolescence differentially influences parvalbumin and perineuronal net immunoreactivity in the medial prefrontal cortex of female, but not male, rats

Brinks, A. S.; Carrica, L. K.; Tagler, D. J.; Gulley, J. M.; Juraska, J. M.

10.1101/2023.08.25.554911 — neuroscience — Posted on 2024-02-28

461 Accelerated signal propagation speed in human neocortical microcircuits

Olah, G.; Lakovics, R.; Shapira, S.; Leibner, Y.; Szucs, A.; Csajbok, E. A.; Barzo, P.; Molnar, G.; Segev, I.; Tamas, G.

10.1101/2022.09.30.510270 — neuroscience — Posted on 2024-02-28

462 Vglut2-based glutamatergic signaling in central noradrenergic neurons is dispensable for normal breathing and chemosensory reflexes

Chang, Y.; Lusk, S.; Chang, A.; Ward, C. S.; Ray, R. S.

10.1101/2023.04.16.535729 — neuroscience — Posted on 2024-02-28

463 Theoretical principles explain the structure of the insect head direction circuit

Aceituno, P. V.; Dall'Osto, D.; Pisokas, I.

10.1101/2023.07.05.547838 — neuroscience — Posted on 2024-02-28

464 A mean-field model of gamma-frequency oscillations in networks of excitatory and inhibitory neurons

Tahvili, F.; Destexhe, A.

10.1101/2023.11.20.567709 — neuroscience — Posted on 2024-02-28

465 Network Statistics of the Whole-Brain Connectome of Drosophila

Lin, A.; Yang, R.; Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. E.; Costa, M.; Eichler, K.; Bates, A. S.; Eckstein, N.; Funke, J.; Jefferis, G. S. X. E.; Murthy, M.

10.1101/2023.07.29.551086 — neuroscience — Posted on 2024-02-28

466 Feedforward and disinhibitory circuits differentially control activity of cortical somatostatin-positive interneurons during behavioral state transitions

De Brito Van Velze, M.; Dhanasobhon, D.; Martinez, M.; Morabito, A.; Berthaux, E.; Martins Pinho, C.; Rebola, N.; Zerlaut, Y.

10.1101/2024.01.10.574973 — neuroscience — Posted on 2024-02-28

467 Distinct representation of cognitive flexibility and habitual stability in the primate putamen, caudate, and ventral striatum

An, S.-y.; Hwang, S.-H.; Lee, K.; Kim, H. F.

10.1101/2024.02.27.579257 — neuroscience — Posted on 2024-02-28

468 Prenatal Stress Alters Transcription of NMDA-Type Glutamate Receptors in the Hippocampus.

Buck, T. G.; Dong, E.; Guidotti, A.; Sodhi, M.

10.1101/2024.02.18.580903 — pharmacology and toxicology — Posted on 2024-02-28

469 Large library docking for cannabinoid-1 receptor agonists with reduced side effects

Tummino, T. A.; Iliopoulos-Tsoutsouvas, C.; Braz, J. M.; O'Brien, E. S.; Stein, R. M.; Craik, V.; Tran, N. K.; Ganapathy, S.; Liu, F.; Shiimura, Y.; Tong, F.; Ho, T. C.; Radchenko, D. S.; Moroz, Y. S.; Rosado, S. R.; Bhardwaj, K.; Benitez, J.; Liu, Y.; Kandasamy, H.; Normand, C.; Semache, M.; Sabbagh, L.; Glenn, I.; Irwin, J. J.; Kumar, K. K.; Makriyannis, A.; Basbaum, A. I.; Shoichet, B. K.

10.1101/2023.02.27.530254 — pharmacology and toxicology — Posted on 2024-02-28

470 The contribution of Mediterranean connectivity to morphological variability in Iron Age sheep of the Eastern Mediterranean

Harding, S. A.; Hadjikoumis, A.; Vermeersch, S.; Marom, N.

10.1101/2022.12.24.521859 — paleontology — Posted on 2024-02-28

471 GIRAFFOIDS FROM THE SIWALIKS OF PAKISTAN

Solounias, N.; Iba, M.

10.1101/2023.10.06.561267 — paleontology — Posted on 2024-02-28

472 KSR1 regulates small-cell lung carcinoma tumor initiation and therapy resistance

Chatterjee, D.; Svoboda, R. A.; Huisman, D. H.; Vieira, H. M.; Rao, C.; Askew, J. W.; Fisher, K. W.; Lewis, R. E.

10.1101/2024.02.23.581815 — cancer biology — Posted on 2024-02-28

473 AlphaFold-SFA: accelerated sampling of cryptic pocket opening, protein-ligand binding and allostery by AlphaFold, slow feature analysis and metadynamics

Vats, S.; Bobrovs, R.; Söderhjelm, P.; Bhakat, S.

10.1101/2023.11.21.568098 — biophysics — Posted on 2024-02-28

474 DiffModeler: Large Macromolecular Structure Modeling in Low-Resolution Cryo-EM Maps Using Diffusion Model

Wang, X.; Zhu, H.; Terashi, G.; Taluja, M.; Kihara, D.

10.1101/2024.01.20.576370 — bioinformatics — Posted on 2024-02-28

475 Long-read genome assembly of the insect model organism Tribolium castaneum reveals spread of satellite DNA in gene-rich regions by recurrent burst events

Volaric, M.; Despot-Slade, E.; Veseljak, D.; Mravinac, B.; Mestrovic, N.

10.1101/2023.04.24.538079 — genomics — Posted on 2024-02-28

476 Immune determinants of pegivirus persistence, control, and cross-species infection in the laboratory mouse

Nennig, K.; Shaw, T.; O'Connor, D.; Stapleton, J.; Bailey, A. L.

10.1101/2024.02.27.582314 — microbiology — Posted on 2024-02-27

477 Engineering an Escherichia coli strain for production of long single-stranded DNA

Shen, K.; Flood, J. J.; Zhang, Z.; Ha, A.; Shy, B.; Dueber, J. E.; Douglas, S. M.

10.1101/2024.02.27.582394 — bioengineering — Posted on 2024-02-27

478 Versatile Functional Interaction between Electrically Silent KV Subunits and KV7 Potassium Channels

Renigunta, V. K.; Xhaferri, N.; Shaikh, I. G.; Schlegel, J.; Bisen, R.; Sanvido, I.; Kalpachidou, T.; Kummer, K.; Oliver, D.; Leitner, M. G.; Lindner, M.

10.1101/2024.02.23.581732 — neuroscience — Posted on 2024-02-27

479 Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.

Thirimanne, H. N.; Bonnin, D. A.; Nuechterlein, N.; Arora, S.; Jensen, M.; Parada, C. A.; Qiu, C.; Szulzewsky, F.; English, C. W.; Chen, W. C.; Sievers, P.; Nassiri, F.; Wang, J. Z.; Klisch, T. J.; Aldape, K. D.; Patel, A. J.; Cimino, P. J.; Zadeh, G.; Sahm, F.; Raleigh, D. R.; Shendure, J.; Ferreira, M.; Holland, E. C.

10.1101/2024.02.23.581766 — cancer biology — Posted on 2024-02-27

480 Emodin modulates PI3K-AKT pathway to inhibit proliferation, invasion and induce apoptosis in glioma cells.

Mir, A. H.; Banday, M. Z.; Aadil, F.; Ganie, S. A.; Shah, E. H.

10.1101/2024.02.23.580874 — cancer biology — Posted on 2024-02-27

481 Ribonanza: deep learning of RNA structure through dual crowdsourcing

He, S.; Huang, R.; Townley, J.; Kretsch, R. C.; Karagianes, T. G.; Cox, D. B. T.; Blair, H.; Penzar, D.; Vyaltsev, V.; Aristova, E.; Zinkevich, A.; Bakulin, A.; Sohn, H.; Krstevski, D.; Fukui, T.; Tatematsu, F.; Uchida, Y.; Jang, D.; Lee, J. S.; Shieh, R.; Ma, T.; Martynov, E.; Shugaev, M. V.; Bukhari, H. S. T.; Fujikawa, K.; Onodera, K.; Henkel, C.; Ron, S.; Romano, J.; Nicol, J. J.; Nye, G. P.; Wu, Y.; Choe, C.; Reade, W.; Eterna participants, ; Das, R.

10.1101/2024.02.24.581671 — biophysics — Posted on 2024-02-27

482 Stimulation Effects Mapping for Standardizing Coil Placement in Transcranial Magnetic Stimulation

Zhong, G.; Yang, Z.; Jiang, T.

10.1101/2024.02.23.581706 — bioengineering — Posted on 2024-02-27

483 Identification of Thioredoxin1 interacting proteins in neuronal cytoskeletal organization during autophagy

Islam, M. I.; Sultana, S.; Padmanabhan, N.; Rashid, M.-u.; Siddiqui, T.; Coombs, K.; Vitiello, P.; Karimi, S.; Eftekharpour, E.

10.1101/2024.02.27.582366 — biochemistry — Posted on 2024-02-27

484 T6SS-associated Rhs toxin containers: Structural and functional insights into bacterial weaponry and self-protection

Kielkopf, C. S.; Shneider, M. M.; Leiman, P. G.; Taylor, N. M. I.

10.1101/2024.02.26.582050 — biochemistry — Posted on 2024-02-27

485 Matching Excellence: ONT's Rise to Parity with PacBio in Genome Reconstruction of Non-Model Bacterium with High GC Content

Soto Serrano, A.; Li, W.; Panah, F.; Hui, Y.; Atienza, P.; Fomenkov, A.; Roberts, R. J.; Deptula, P.; Krych, L.

10.1101/2024.02.26.582104 — genomics — Posted on 2024-02-27

486 Integrative genomics sheds light on the immunobiology of tuberculosis in cattle

O'Grady, J. F.; McHugo, G. P.; Ward, J. A.; Hall, T. J.; Faherty O'Donnell, S. L.; Correia, C. N.; Browne, J. A.; McDonald, M.; Gormley, E.; Riggio, V.; Prendergast, J. G. D.; Clark, E. L.; Pausch, H.; Meade, K. G.; Gormley, I. C.; Gordon, S. V.; MacHugh, D. E.

10.1101/2024.02.27.582295 — genomics — Posted on 2024-02-27

487 A high throughput CRISPR perturbation screen identifies epigenetic regulators impacting primordial germ cell development

Li, L.; Ding, X.; Sheft, A.; Schimenti, J. C.

10.1101/2024.02.26.582097 — developmental biology — Posted on 2024-02-27

488 Spatiotemporal dynamics of NF-κB/Dorsal inhibitor IκBα/Cactus in Drosophila blastoderm embryos

Schloop, A. E.; Hiremath, S. V.; Shaikh, R.; Williams, C. M.; Reeves, G. T.

10.1101/2024.02.23.581825 — developmental biology — Posted on 2024-02-27

489 The Mayo Clinic Salivary Tissue-Organoid Biobanking: A Resource for Salivary Regeneration Research

Aalam, S. M. M.; Varela, A. R.; Khaderi, A.; Mondesir, R. J.; Mun, D.-G.; Ding, A. Z.; Lombaert, I. M. A.; Coppes, R. P.; Emperumal, C. P.; Pandey, A.; Janus, J. R.; Kannan, N.

10.1101/2024.02.23.581761 — cell biology — Posted on 2024-02-27

490 A multi-looping chromatin signature predicts dysregulated gene expression in neurons with familial Alzheimer's disease mutations

Chandrashekar, H.; Simandi, Z.; Choi, H.; Ryu, H.-S.; Waldman, A. J.; Nikish, A.; Muppidi, S. S.; Gong, W.; Paquet, D.; Phillips-Cremins, J. E.

10.1101/2024.02.27.582395 — molecular biology — Posted on 2024-02-27

491 Essential functions of Inositol hexakisphosphate (IP6) in Murine Leukemia Virus replication

Biswas, B.; Lai, K. K.; Bracey, H.; Datta, S. A. K.; Harvin, D.; Sowd, G. A.; Aiken, C.; Rein, A.

10.1101/2024.02.27.581940 — molecular biology — Posted on 2024-02-27

492 Proteomic Analysis of Urine from Youths Indulging in Gaming

Yang, M.; Liu, Y.; Shen, Z.; Wang, H.; Gao, Y.

10.1101/2024.02.26.581984 — molecular biology — Posted on 2024-02-27

493 Interaction between a J-domain co-chaperone and a specific Argonaute protein contributes to microRNA function in animals

Frederick, P.-M.; Jannot, G.; Banville, I.; Simard, M. J.

10.1101/2024.02.27.581607 — molecular biology — Posted on 2024-02-27

494 Profound synthetic lethality between SMARCAL1 and FANCM

Feng, S.; Liu, K.; Shang, J.; Hoeg, L.; Yang, W.; Roy, S.; Young, J. T.; Wu, W.; Xu, D.; Durocher, D.

10.1101/2024.02.27.582393 — molecular biology — Posted on 2024-02-27

495 A versatile reporter system to study cell-to-cell and cell-free bovine leukemia virus infection

Rammauro, F.; Flo, M.; Carrion, F.; Ortega, C.; Di Nunzio, F.; Vallmitjana, A.; Pritsch, O.; Olivero, N.

10.1101/2024.02.26.581980 — microbiology — Posted on 2024-02-27

496 Stable flies harbor a low complexity microbiota dominated by mastitis-associated bacteria

Sommer, A. J.; Kettner, J. E.; Coon, K. L.

10.1101/2024.02.27.582344 — microbiology — Posted on 2024-02-27

497 A Caenorhabditis elegans based system for high-throughput functional phenotyping of human gut microbiota

Ambat, A.; Thayyil Valappil, V.; Ghimire, S.; Harnvoravongchai, P.; Mishra, S.; Vijayan Pillai, V.; Kashyap, P.; Scaria, J.

10.1101/2024.02.27.582212 — microbiology — Posted on 2024-02-27

498 Emergence of bluetongue virus serotype 3 in western Germany, October 2023, and ad-hoc monitoring in Culicoides biting midges

Voigt, A.; Kampen, H.; Heuser, E.; Zeiske, S.; Hoffmann, B.; Hoeper, D.; Holsteg, M.; Sick, F.; Ziegler, S.; Wernike, K.; Beer, M.; Werner, D.

10.1101/2024.02.26.582175 — microbiology — Posted on 2024-02-27

499 Decoupling the molecular versatility of aminoglycosides via drug or target modification enables community-wide antiphage defense

Kever, L.; Zhang, Q.; Hardy, A.; Westhoff, P.; Yu, Y.; Frunzke, J.

10.1101/2024.02.27.582341 — microbiology — Posted on 2024-02-27

500 Evaluating treatments for the protection of grapevine pruning wounds from natural infection by trunk disease fungi

Leal, C.; Bujanda, R.; Manzanares, B. L.; Ojeda, S.; Berbegal, M.; Llop, A. V.; Santesteban, L. G.; Palacios, J.; Gramaje, D.

10.1101/2024.02.27.582328 — microbiology — Posted on 2024-02-27

501 Single-cell approach dissecting agr quorum sensing dynamics in Staphylococcus aureus

Baer, J.; Charlton, S. G. V.; Tarnutzer, A.; Ugolini, G. S.; Secchi, E.; Zinkernagel, A. S.

10.1101/2024.02.27.582246 — microbiology — Posted on 2024-02-27

502 Reliably Measuring Learning-Dependent Distractor Suppression with Eye Tracking

Kim, A. J.; Gregoire, L.; Anderson, B. A.

10.1101/2024.02.23.581757 — neuroscience — Posted on 2024-02-27

503 TISSUE-SPECIFIC METABOLOMIC REPROGRAMMING DETERMINES THE DISEASE PATHOPHYSIOLOGY OF SARS-COV-2 VARIANTS IN HAMSTER MODEL

Sardarni, U. K.; Ambikan, A.; Acharya, A.; Johnson, S. D.; Avedissian, S. N.; Vegvari, A.; Neogi, U.; Byrareddy, S.

10.1101/2024.02.25.581989 — systems biology — Posted on 2024-02-27

504 SIGNAL-seq: Multimodal Single-cell Inter- and Intra-cellular Signalling Analysis

Opzoomer, J. W.; O'Sullivan, R.; Sufi, J.; Madsen, R. R.; Qin, X.; Basiarz, E.; Tape, C. J.

10.1101/2024.02.23.581433 — cancer biology — Posted on 2024-02-27

505 CapP mediates the structural formation of biofilm-specific pili in the opportunistic human pathogen Bacillus cereus

Alvarez-Mena, A.; Shukkoor, M. B. A.; Caro-Astorga, J.; Berbon, M.; Gomez, M. L. A.; Grelard, A.; Kauffmann, B.; Morvan, E.; de Vicente, A.; Loquet, A.; Romero, D.

10.1101/2024.02.27.582368 — microbiology — Posted on 2024-02-27

506 Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis

Tian, X.; Gao, Y.; Ma, W.; Zhang, J.; Ju, Y.; Ding, J.; Zeng, S.; Hameed, A.; Zhong, N.; Cook, G. M.; Hu, J.; zhang, T.

10.1101/2024.02.27.582260 — microbiology — Posted on 2024-02-27

507 Discovery of an anti-virulence compound that targets the Staphylococcus aureus SaeRS two-component system to inhibit toxic shock syndrome toxin 1 (TSST-1) production

Dufresne, K.; DiMaggio, D. A.; Maduta, C. S.; Brinsmade, S. R.; McCormick, J. K.

10.1101/2024.02.27.582338 — microbiology — Posted on 2024-02-27

508 Nitrogen cycling during an Arctic bloom: from chemolithotrophy to nitrogen assimilation

Laso Perez, R.; Rivas Santisteban, J.; Fernandez-Gonzalez, N.; Mundy, C. J.; Tamames, J.; Pedros-Alio, C.

10.1101/2024.02.27.582273 — microbiology — Posted on 2024-02-27

509 Spatial control of sensory adaptation modulates mechanosensing in Pseudomonas aeruginosa

Patino, R.; Kuhn, M. J.; Macmillan, H.; Inclan, Y.; Chavez, I.; Von Dollen, J.; Johnson, J. R.; Swaney, D. L.; Krogan, N.; Persat, A.; Engel, J.

10.1101/2024.02.27.582188 — microbiology — Posted on 2024-02-27

510 Resisting the resistance: The antimicrobial peptide DGL13K selects for small colony variants of Staphylococcus aureus that show increased resistance to its stereoisomer LGL13K, but not to DGL13K.

Gorr, S.-U.

10.1101/2024.02.26.582211 — microbiology — Posted on 2024-02-27

511 Coordination between cytoskeletal organization, cell contraction and extracellular matrix development, is depended on LOX for aneurysm prevention

Hasson, P.; Aviram, R.; Zaffryar-Eilot, S.; Kaganovsky, A.; Odeh, A.; Melamed, S.; Militsin, R.; Pinnock, C. B.; Shemesh, A.; Palty, R.; Ganesh, S. K.

10.1101/2024.02.23.581837 — cell biology — Posted on 2024-02-27

512 Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity

10.1101/2024.02.27.582371 — microbiology — Posted on 2024-02-27

513 Sequence modeling and design from molecular to genome scale with Evo

Nguyen, E.; Poli, M.; Durrant, M. G.; Thomas, A. W.; Kang, B.; Sullivan, J.; Ng, M. Y.; Lewis, A.; Patel, A.; Lou, A.; Ermon, S.; Baccus, S. A.; Hernandez-Boussard, T.; Re, C.; Hsu, P. D.; Hie, B. L.

10.1101/2024.02.27.582234 — synthetic biology — Posted on 2024-02-27

514 Paced Breathing With a Prolonged Inspiratory Period Increases Sympathetic Activity: A Heart and Brain Analysis

Joaquim, M. S.; Moreira, C.

10.1101/2024.02.23.581710 — physiology — Posted on 2024-02-27

515 Development and validation of a gene expression score to account for tumour purity and improve prognostication in breast cancer

Barreca, M.; Dugo, M.; Galbardi, B.; Gyorrfy, B.; NA-PHER2 consortium, ; NeoTRIP consortium, ; Valagussa, P.; Besozzi, D.; Viale, G.; Bianchini, G.; Gianni, L.; Callari, M.

10.1101/2024.02.23.581701 — bioinformatics — Posted on 2024-02-27

516 Limiting Brownian Motion to Enhance Immunogold Phenotyping and Superimpose Optical and Non-Optical Single-EP Analyses

Nguyen, K. T.; Rima, X. Y.; Hisey, C. L.; Doon-Ralls, J.; Nagaraj, C. K.; Reategui, E.

10.1101/2024.02.22.581663 — bioengineering — Posted on 2024-02-27

517 Prediction of neural activity in connectome-constrained recurrent networks

Beiran, M.; Litwin-Kumar, A.

10.1101/2024.02.22.581667 — neuroscience — Posted on 2024-02-27

518 Changes in the analgesic mechanism of oxytocin can contribute to hyperalgesia in Parkinsons disease model rats

Usami, N.; Maegawa, H.; Niwa, H.

10.1101/2024.02.23.581716 — neuroscience — Posted on 2024-02-27

519 Subjective confidence modulates individual BOLD patterns of predictive processing

Hechler, A.; de Lange, F.; Riedl, V.

10.1101/2024.02.23.581697 — neuroscience — Posted on 2024-02-27

520 Yerba mate (Ilex paraguariensis) genome provides new insights into convergent evolution of caffeine biosynthesis

Vignale, F. A.; Hernandez Garcia, A.; Modenutti, C. P.; Sosa, E. J.; Defelipe, L. A.; Oliveira, R. R. M.; Nunes, G. L.; Acevedo, R. M.; Burguener, G. F.; Rossi, M.; Zapata, P. D.; Marti, D. A.; Sansberro, P. A.; Oliveira, G.; Smith, M. N.; Dubs, N. M.; Nair, S.; Barkman, T. J.; Turjanski, A. G.

10.1101/2023.09.08.556846 — plant biology — Posted on 2024-02-27

521 The MODY-associated KCNK16 L114P mutation increases islet glucagon secretion and limits insulin secretion resulting in transient neonatal diabetes and glucose dyshomeostasis in adults

Nakhe, A. Y.; Dadi, P. K.; Kim, J.; Dickerson, M. T.; Behera, S.; Dobson, J. R.; Shrestha, S.; Cartailler, J.-P.; Sampson, L.; Magnuson, M. A.; Jacobson, D. A.

10.1101/2023.06.20.545631 — physiology — Posted on 2024-02-27

522 Association of Macular Pigment Density with Plasma Macular Carotenoids levels, And lipids in Indian patients with early Age-Related Macular Degeneration

Srinivasan, S.; Rajendran, A.; Panneerselvam, B.; Uduman, M. S.

10.1101/2024.02.23.581712 — pharmacology and toxicology — Posted on 2024-02-27

523 MICROCOSM FABRICATION PLATFORM FOR LIVE MICROSCOPY OF PLANT-SOIL SYSTEMS

Liu, Y.; Patko, D.; de le Mata, A. L.; Dong, X.; Peral, E. G.; He, X.; Ameduri, B.; Ladmiral, V.; MacDonald, M. P.; Dupuy, L. X.

10.1101/2024.02.23.581454 — bioengineering — Posted on 2024-02-27

524 Woman the Hunter? Female foragers sometimes hunt, yet gendered divisions of labor are real

Venkataraman, V. V.; Hoffman, J.; Hames, R. B.; Stibbard-Hawkes, D. N. E.; Kramer, K.; Kelly, R.; Farquharson, K.; Hagen, E. H.; Hewlett, B. S.; DAvis, H. E.; Glowacki, L.; Jang, H.; Syne, K.; Starkweather, K.; Lew-Levy, S.

10.1101/2024.02.23.581721 — evolutionary biology — Posted on 2024-02-27

525 Stereotyped cell lineage trees support robust development

Zhang, X.; Li, Z.; Chen, J.; Yang, W.; Wu, P.; Chen, F.; He, X.; Chen, X.; Yang, J.-R.

10.1101/2024.02.23.581522 — developmental biology — Posted on 2024-02-27

526 Regulation of defense strategies and host metabolism to survive neonatal infection

Wu, Z.; Tien, N. T. N.; Baek, O.; Zhong, J.; Klabunde, B.; Yen, N. T. H.; Long, N. P.; Nguyen, D. N.

10.1101/2024.02.23.581534 — immunology — Posted on 2024-02-27

527 Directed neural interactions in fMRI: a comparison between Granger Causality and Effective Connectivity

Allegra, M.; Gilson, M.; Brovelli, A.

10.1101/2024.02.22.581068 — neuroscience — Posted on 2024-02-27

528 Estimating Directed Connectivity with OPM-MEG: A Feasibility Study

Pedersen, M.; Vashista, G.; Henare, D.; Sowman, P. F.

10.1101/2024.02.22.581475 — neuroscience — Posted on 2024-02-27

529 What Does Large-scale Electrodermal Sensing Reveal?

McDuff, D.; Thomson, S.; Abdel-Ghaffar, S.; Galatzer-Levy, I.; Poh, M.-Z.; Sunshine, J.; Barakat, A.; Heneghan, C.; Sunden, L.

10.1101/2024.02.22.581472 — physiology — Posted on 2024-02-27

530 Directed biomechanical compressive forces enhance fusion efficiency in model placental trophoblast cultures

Parameshwar, P. K.; Li, C.; Arnauts, K.; Jiang, J.; Rostami, S.; Campbell, B. E.; Lu, H.; Rosenzweig, D. H.; Vaillancourt, C.; Moraes, C.

10.1101/2024.02.22.581638 — biophysics — Posted on 2024-02-27

531 A Multi-Omics Atlas of Sex-Specific Differences in Obstructive Hypertrophic Cardiomyopathy

Garmany, R.; Dasari, S.; Bos, J. M.; Kim, E. T.; Martinez, K. A.; Tester, D. J.; dos Remedios, C.; Maleszewski, J. J.; Dearani, J. A.; Ommen, S. R.; Geske, J. B.; Guidicessi, J. R.; Ackerman, M. J.

10.1101/2024.02.22.581621 — bioinformatics — Posted on 2024-02-27

532 Fair molecular feature selection unveils universally tumor lineage-informative methylation sites in colorectal cancer

Li, X. C.; Liu, Y.; Schaffer, A. A.; Mount, S.; Sahinalp, S. C.

10.1101/2024.02.22.580595 — bioinformatics — Posted on 2024-02-27

533 CloVarS: a simulation of single-cell clonal variability

Faccioni, J. L.; Buss, J. H.; Begnini, K. R.; Brunnet, L. G.; Oliveira, M. M.; Lenz, G.

10.1101/2024.02.22.581631 — bioinformatics — Posted on 2024-02-27

534 Facilitate integrated analysis of single cell multiomic data by binarizing gene expression values

Misra, R.; Ferrena, A.; Zheng, D.

10.1101/2024.02.22.581665 — bioinformatics — Posted on 2024-02-27

535 Changes in cognition and neuroinflammation in a rodent model of chemotherapy-induced cognitive impairment are variable both acutely and chronically

Haller, O. J.; Semendric, I.; Collins-Praino, L. E.; Whittaker, A. E.; George, R. P.

10.1101/2024.02.22.581658 — animal behavior and cognition — Posted on 2024-02-27

536 Friend, food, or foe: sea anemones discharge fewer nematocysts at familiar anemonefish after delayed mucus adaptation.

Hoepner, C. M.; Fobert, E. K.; Rudd, D.; Petersen, O.; Abbott, C. A.; Burke da Silva, K.

10.1101/2024.02.22.581653 — ecology — Posted on 2024-02-27

537 Unveiling Movement Intention after Stroke: Integrating EEG and EMG for Motor Rehabilitation

Lopez-Larraz, E.; Sarasola-Sanz, A.; Birbaumer, N.; Ramos-Murguialday, A.

10.1101/2024.02.22.581596 — neuroscience — Posted on 2024-02-27

538 Reference curves for harmonizing multi-site regional diffusion MRI metrics across the lifespan

Zhu, A. H.; Nir, T. M.; Javid, S.; Villalon-Reina, J. E.; Rodrigue, A. L.; Strike, L. T.; de Zubicaray, G. I.; McMahon, K. L.; Wright, M. J.; Medland, S. E.; Blangero, J. E.; Glahn, D. C.; Kochunov, P.; Haberg, A. K.; Thompson, P. M.; Jahanshad, N.

10.1101/2024.02.22.581646 — neuroscience — Posted on 2024-02-27

539 Spontaneous pain dynamics characterized by stochasticity in awake human LFP with chronic pain

Ryu, J.; Kao, J. C.; Bari, A.

10.1101/2024.02.22.581655 — neuroscience — Posted on 2024-02-27

540 Neuronal and behavioral responses to naturalistic texture images in macaque monkeys

Ziemba, C. M.; Goris, R. L. T.; Stine, G. M.; Perez, R. K.; Simoncelli, E. P.; Movshon, J. A.

10.1101/2024.02.22.581645 — neuroscience — Posted on 2024-02-27

541 Brain preparedness: The cortisol awakening response proacts dynamic organization of large-scale brain networks across emotional and executive functions

Zeng, Y.; Xiong, B.; Gao, H.; Liu, C.; Chen, C.; Wu, J.; Qin, S.

10.1101/2024.02.22.581523 — neuroscience — Posted on 2024-02-27

542 A patient-derived amyotrophic lateral sclerosis blood-brain barrier cell model reveals focused ultrasound-mediated anti-TDP-43 antibody delivery.

Wasielewska, J. M.; Castro Cabral-da-Silva, M.; Pecoraro, M.; Nguyen, T. H.; La Bella, V.; Oikari, L. E.; Ooi, L.; White, A. R.

10.1101/2024.02.22.581567 — neuroscience — Posted on 2024-02-27

543 Optogenetic fMRI reveals therapeutic circuits of subthalamic nucleus deep brain stimulation

Li, Y.; Lee, S.; Yu, C.; Hsu, L.-M.; Wang, T.-W. W.; Do, K.; Kim, H.-J.; Shih, Y.-Y. I.; Grill, W. M.

10.1101/2024.02.22.581627 — neuroscience — Posted on 2024-02-27

544 MRI mapping of hemodynamics in the human spinal cord

Hemmerling, K. J.; Hoggarth, M. A.; Sandhu, M. S.; Parrish, T. B.; Bright, M. G.

10.1101/2024.02.22.581606 — physiology — Posted on 2024-02-27

545 A biomimetic fruit fly robot for studying the neuromechanics of legged locomotion

Goldsmith, C.; Haustein, M.; Bueschges, A.; Szczecinski, N. S.

10.1101/2024.02.22.581436 — bioengineering — Posted on 2024-02-27

546 Relapse after intermittent access to cocaine: Discriminative cues more effectively trigger drug seeking than do conditioned cues

Ndiaye, N. A.; Abu Shamleh, S.; Casale, D.; Castaneda Ouellet, S.; Laplante, I.; Robinson, M. J. F.; Samaha, A.

10.1101/2024.02.22.580659 — animal behavior and cognition — Posted on 2024-02-27

547 Modeling soybean growth: A mixed model approach

DELATTRE, M.; Toda, Y.; Tressou, J.; Iwata, H.

10.1101/2023.06.13.544713 — genetics — Posted on 2024-02-27

548 finsyncR, an R package to synchronize 27 years of fish and invertebrate data across the United States

Mahon, M. B.; Jones, D. K.; Hill, R. A.; Brown, T. N.; Brown, E. A.; Kunz, S.; Rumschlag, S. L.

10.1101/2024.02.22.581615 — ecology — Posted on 2024-02-27

549 Single-neuron spiking variability in hippocampus dynamically tracks sensory content during memory formation in humans

Waschke, L.; Kamp, F.; van den Elzen, E.; Krishna, S.; Lindenberger, U.; Rutishauser, U.; Garrett, D. D.

10.1101/2023.02.23.529684 — neuroscience — Posted on 2024-02-27

550 Individualized temporal patterns dominate cortical upstate and sleep depth in driving human sleep spindle timing

Chen, S.; He, M.; Brown, R. E.; Eden, U. T.; Prerau, M. J.

10.1101/2024.02.22.581592 — neuroscience — Posted on 2024-02-27

551 Resilience and vulnerability of speech neural tracking to early auditory deprivation

Federici, A.; Fantoni, M.; Pavani, F.; Handjaras, G.; Bednaya, E.; Martinelli, A.; Berto, M.; Ricciardi, E.; Nava, E.; Orzan, E.; Bianchi, B.; Bottari, D.

10.1101/2024.02.22.581545 — neuroscience — Posted on 2024-02-27

552 SMAC mimetics overcome apoptotic resistance in ovarian cancer through MSLN-TNF alpha axis

Coelho, R.; Seashore-Ludlow, B.; Schutz, S.; Christopher Lombardo, F.; Moussaud-Lamodiere, E.; Casanova, R.; Ficek-Pascual, J.; Brunhilde Labrosse, K.; Hensle, M.; Lopez-Nunez, M.; Rimmer, N.; Fedier, A.; Lima, R.; Montavon Sartorius, C.; Kurzeder, C.; Singer, F.; Bertolini, A.; The TumorProfiler Consortium, ; Fucikova, J.; Ratsch, G.; Bodenmiller, B.; Kallioniemi, O.; Ostling, P.; David, L.; Heinzelmann-Schwarz, V.; Jacob, F.

10.1101/2024.01.24.576987 — cancer biology — Posted on 2024-02-27

553 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K

Zheng, L.; Zhou, B.; Wu, B.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Hong, L.

10.1101/2023.10.18.562890 — biophysics — Posted on 2024-02-27

554 Analysis of multi-condition single-cell data with latent embedding multivariate regression

Ahlmann-Eltze, C.; Huber, W.

10.1101/2023.03.06.531268 — bioinformatics — Posted on 2024-02-27

555 Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq

Noble, J. C.; Lentini, A.; Hageman-Jensen, M.; Sandberg, R.; Reinius, B.

10.1101/2024.02.06.579116 — molecular biology — Posted on 2024-02-27

556 Temporal dynamics of short-term neural adaptation across human visual cortex

Brands, A. M.; Devore, S.; Devinsky, O.; Doyle, W.; Flinker, A.; Friedman, D.; Dugan, P.; Winawer, J.; Groen, I. I. A.

10.1101/2023.09.13.557378 — neuroscience — Posted on 2024-02-27

557 Longitudinal Changes in Value-based Learning in Middle Childhood: Distinct Contributions of Hippocampus and Striatum

Falck, J.; Zhang, L.; Raffington, L.; Mohn, J. J.; Triesch, J.; Heim, C.; Shing, Y. L.

10.1101/2023.04.13.536699 — neuroscience — Posted on 2024-02-27

558 Criterion placement threatens the construct validity of neural measures of consciousness

Fahrenfort, J. J.; Johnson, P. A.; Kloosterman, N. A.; Stein, T.; van Gaal, S.

10.1101/2024.02.22.581517 — neuroscience — Posted on 2024-02-27

559 High-Performance Wide-Band Open-Source System for Acoustic Stimulation

Silva, A.; Carvalho, F.; Cruz, B. F.

10.1101/2024.02.22.581424 — neuroscience — Posted on 2024-02-27

560 Overexpressing NRT2.7 induces nitrate export from the vacuole and increases growth of Arabidopsis

Armengaud, P.; De Angeli, A.; Berquin, P.; Brehaut, V.; Durand, M.; Daniel-Vedele, F.; Krapp, A.; Filleur, S.

10.1101/2024.02.26.582130 — plant biology — Posted on 2024-02-27

561 Grapevine Rootstock and Scion Genotypes' Symbiosis with Soil Microbiome: A Machine Learning Revelation for Climate-Resilient Viticulture

Anand, L.; Gentimis, T.; Downie, A. B.; Lopez, C. M. R.

10.1101/2024.02.25.581926 — plant biology — Posted on 2024-02-27

562 GhCPK28 negatively regulates the immune response by phosphorylating GhTIFY3b

Gao, S.; Shao, W.; Wu, J.; Zhao, Z.; Hu, W.; Shao, P.; Hua, J.; Zou, B.; Huang, Q.

10.1101/2024.02.23.581816 — plant biology — Posted on 2024-02-27

563 Functional marker CAPS-799 of the TaPHT1;9-4B gene is useful for screening phosphorus-efficient wheat cultivars

Guozhang, K.; Jinfeng, W.; Zedong, C.; Huanting, S.; Chuang, L.; Kaixia, F.; Bo, Y.; Tiancai, G.; Yonghua, W.; Pengfei, W.

10.1101/2024.02.23.581827 — plant biology — Posted on 2024-02-27

564 Photoreceptor-induced sinapate synthesis contributes to photoprotection in Arabidopsis

Leonardelli, M.; Tissot, N.; Podolec, R.; Ares-Orpel, F.; Glauser, G.; Ulm, R.; Demarsy, E.

10.1101/2024.02.26.582123 — plant biology — Posted on 2024-02-27

565 Novel transcriptional activator TAC3 regulates age-dependent floral transition in Chinese fir

Wu, Q.; Li, J.; Zhu, T.; Chang, H.; Wang, X.; Su, J.

10.1101/2024.02.27.582233 — plant biology — Posted on 2024-02-27

566 Nicotine has a minor role in protecting field-grown Nicotiana benthamiana against insect herbivory

Negin, B.; Wang, F.; Fischer, H. D.; Jander, G.

10.1101/2024.02.26.582111 — plant biology — Posted on 2024-02-27

567 SHOOTMERISTEMLESS autoactivation: A prerequisite for fruit metamorphosis

Dong, Y.; Hu, Z.-C.; Majda, M.; Sun, H.-R.; Zhang, Y.; Ding, Y.-N.; Yuan, Q.; Su, T.-B.; Lv, T.-F.; Gao, F.; Xu, G.; Smith, R. S.; Ostergaard, L.

10.1101/2024.02.23.581830 — plant biology — Posted on 2024-02-27

568 Cold hardiness-informed budbreak reveals role of freezing temperatures and daily fluctuation in chill accumulation model

North, M. G.; Workmaster, B. A.; Atucha, A.; Kovaleski, A. P.

10.1101/2024.02.25.581952 — plant biology — Posted on 2024-02-27

569 A missense mutation in the gene encoding the Mg-chelatase subunit I leads to a viable pale green line with phenotypic features of potential interest for barley breeding programs

Persello, A.; Tadini, L.; Rotasperti, L.; Ballabio, F.; Tagliani, A.; Torricella, V.; Jahns, P.; Dalal, A.; Moshelion, M.; Camilloni, C.; Rosignoli, S.; Hansson, M.; Cattivelli, L.; Horner, D. S.; Rossini, L.; Tondelli, A.; Salvi, S.; Pesaresi, P.

10.1101/2024.02.24.581867 — plant biology — Posted on 2024-02-27

570 Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals

Lewis, C. T. A.; Melhedegaard, E. G.; Ognjanovic, M. M.; Olsen, M. S.; Laitila, J.; Seaborne, R. A. E.; Gronset, M. N.; Zhang, C.; Iwamoto, H.; Hessel, A. L.; Kuehn, M. N.; Merino, C.; Amigo, N.; Frobert, O.; Giroud, S.; Staples, J. F.; Goropashnaya, A. V.; Fedorov, V. B.; Barnes, B. M.; Toien, O.; Drew, K. L.; Sprenger, R. J.; Ochala, J.

10.1101/2023.11.14.566992 — physiology — Posted on 2024-02-27

571 Biomechanical Modeling of Cesarean Section Scars and Scar Defects

Scott, A. K.; Louwagie, E. M.; Myers, K. M.; Oyen, M. L.

10.1101/2023.11.03.565565 — bioengineering — Posted on 2024-02-27

572 The membrane insertion of the pro-apoptotic protein Bax is a Tom22-dependent multi-step process: a study in nanodiscs

Rouchidane Eyitayo, A.; Daury, L.; Priault, M.; Manon, S.

10.1101/2024.02.16.580668 — biochemistry — Posted on 2024-02-27

573 Design, optimization, and inference of multiphasic decay of infectious virus particles

Seurat, J.; Gerbino, K. R.; Meyer, J. R.; Borin, J. M.; Weitz, J. S.

10.1101/2024.02.23.581735 — microbiology — Posted on 2024-02-27

574 Altered hepatic metabolism mediates sepsis preventive effects of reduced glucose supply in infected preterm newborns

Baek, O.; Muk, T.; Wu, Z.; Ye, Y.; Khakimov, B.; Casano, A. M.; Gangadharan, B.; Bilic, I.; Brunse, A.; Sangild, P. T.; Nguyen, D. N.

10.1101/2023.09.11.557116 — immunology — Posted on 2024-02-27

575 Prioritizing Metabolic Gene Regulators through Multi-Omic Network Integration in Maize

Gomez-Cano, F. A.; Rodriguez, J.; Zhou, P.; Chu, Y.-H.; Magnusson, E.; Gomez-Cano, L.; Krishnan, A.; Springer, N. M.; de Leon, N.; Grotewold, E.

10.1101/2024.02.26.582075 — plant biology — Posted on 2024-02-27

576 New Dual Inducible Cellular Model to Investigate Temporal Control of Oncogenic Cooperating Genes

Kent, M. R.; Jay, A. N.; Kendall, G. C.

10.1101/2024.02.23.581802 — cancer biology — Posted on 2024-02-27

577 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.

10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-02-27

578 Canonical AREs are tumor suppressive regulatory elements in the prostate

Augello, M. A.; Chen, X.; Liu, D.; Lin, K.; Hakansson, A.; Sjostrom, M.; Khani, F.; Deonarine, L. D.; Liu, Y.; Travascio-Green, J.; Wu, J.; Loda, M.; Feng, F. Y.; Robinson, B. D.; Davicioni, E.; Sboner, A.; Barbieri, C.

10.1101/2024.02.23.581466 — cancer biology — Posted on 2024-02-27

579 High-confidence calling of normal epithelial cells allows identification of a novel stem-like cell state in the colorectal cancer microenvironment

Wei, T.-T.; Blanc, E.; Peidli, S.; Bischoff, P.; Trinks, A.; Horst, D.; Sers, C.; Bluthgen, N.; Beule, D.; Morkel, M.; Obermayer, B.

10.1101/2024.02.23.581690 — cancer biology — Posted on 2024-02-27

580 Synergistic and antagonistic drug-drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Kalkan, F. N.; Yildiz, M. S.; Temamogullari Wood, E.; Farid, M.; McCoy, M.; Zhang, C. C.; Posner, B.; Chung, S. S.; Toprak, E.

10.1101/2024.02.23.581821 — cancer biology — Posted on 2024-02-27

581 Induction of expansion of ex vivo NK cells using a new feeder cell built in Brazil. An extended flow cytometry evaluation of K562.mbIL21.4BBL

Watanabe, C. M.; Ishihama Suzuki, C.; Marins dos Santos, A.; Aloia, T. P. A.; Lee, G.; Wald, D.; Okamoto, O. K.; Azevedo, J. T. C. d.; Godoy, J. A. P. d.; Santos, F. P. S.; Weinlich, R.; Kerbauy, L. N.; Kutner, J. M.; Paiva, R. d. M. A.; Hamerschlak, N.

10.1101/2024.02.23.581719 — cancer biology — Posted on 2024-02-27

582 NINJ1 regulates ferroptosis via xCT antiporter interaction and CoA modulation

Chen, S.-Y.; Lin, C.-C.; Wu, J.; Chen, Y.; Wang, Y.-E.; Setayeshpour, Y.; Mestre, A.; Chi, J.-T. A.

10.1101/2024.02.22.581432 — cancer biology — Posted on 2024-02-27

583 Attentional inhibition by alpha power is modulated by faster theta rhythm and audio-visual congruency during natural speech perception

Byczynski, G. E.; Park, H.

10.1101/2024.02.25.581860 — neuroscience — Posted on 2024-02-27

584 The spatiotemporal dynamics of bottom-up and top-down processing during at-a-glance reading

Flower, N.; Pylkkänen, L.

10.1101/2024.02.26.582140 — neuroscience — Posted on 2024-02-27

585 PL-PatchSurfer3: Improved Structure-Based Virtual Screening for Structure Variation Using 3D Zernike Descriptors

Shin, W.-H.; Kihara, D.

10.1101/2024.02.22.581511 — bioinformatics — Posted on 2024-02-27

586 RAMEN Unveils Clinical Variable Networks for COVID-19 Severity and Long COVID Using Absorbing Random Walks and Genetic Algorithms

Xiong, Y.; Wang, J.; Shang, X.; Chen, T.; Fraser, D. D.; Fonseca, G.; Rousseau, S.; Ding, J.

10.1101/2023.01.24.525413 — bioinformatics — Posted on 2024-02-27

587 Short-term memory, attentional control and brain size in primates

van Schaik, C.; Jacobs, I.; Burkart, J. M.; Sauciuc, G.-A.; Schuppli, C.; Persson, T.; Song, Z.

10.1101/2024.02.26.582100 — animal behavior and cognition — Posted on 2024-02-27

588 Pose estimation-based visual perception system for analyzing fish swimming

Wu, X.; Huang, J.; Wang, L.

10.1101/2022.09.07.507033 — animal behavior and cognition — Posted on 2024-02-27

589 Temporal Analysis of Pituitary Transcriptional Dynamics in Mice Models of Hypopituitarism During Postnatal Development

Marques, J. M.; Chang, C. v.; Trigueiro, N. S.; Araujo, R. V.; Cirqueira, C. S.; Russo, L. C.; Viscardi, B. A.; Mendonca, B.; Hoch, N. C.; Carvalho, L. R.

10.1101/2024.02.26.582133 — developmental biology — Posted on 2024-02-27

590 Transcriptomic analysis of the human habenula in schizophrenia

Yalcinbas, E. A.; Ajanaku, B.; Nelson, E. D.; Garcia-Flores, R.; Montgomery, K. D.; Stolz, J. M.; Wu, J.; Divecha, H. R.; Chandra, A.; Bharadwaj, R. A.; Bach, S.; Rajpurohit, A.; Tao, R.; Shin, J.-H.; Kleinman, J. E.; Hyde, T. M.; Weinberger, D. R.; Huuki-Myers, L. A.; Collado-Torres, L.; Maynard, K. R.

10.1101/2024.02.26.582081 — neuroscience — Posted on 2024-02-27

591 The unreasonable effectiveness of the total quasi-steady state approximation, and its limitations

Eilertsen, J.; Schnell, S.; Walcher, S.

10.1101/2023.09.28.559798 — systems biology — Posted on 2024-02-27

592 Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information

Xu, D.; Ando, N.

10.1101/2023.12.08.570849 — biophysics — Posted on 2024-02-27

593 In silico Study of the Uncertainly Significant VCP Variants reveal major Structural, Functional fluctuations leading to potential Disease-Based Associations

DAS, T.; ROYCHOWDHURY, S.; DAS, P.

10.1101/2023.11.04.565542 — genomics — Posted on 2024-02-27

594 Genetic similarity between relatives provides evidence on the presence and history of assortative mating

Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.

10.1101/2023.06.27.546663 — genetics — Posted on 2024-02-27

595 Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration

Pera, E. M.; Nilsson-De Moura, J.; Pomeshchik, Y.; Roybon, L.; Milas, I.

10.1101/2023.09.05.556243 — developmental biology — Posted on 2024-02-27

596 Control of ciliary transcriptional programs during spermatogenesis by antagonistic transcription factors

Wang, W.; Xing, J.; Zhang, X.; Liu, H.; Jiang, H.; Xu, C.; Zhao, X.; Hu, Z.

10.1101/2024.01.01.573824 — cell biology — Posted on 2024-02-27

597 Distinct streams for supervised and unsupervised learning in the visual cortex

Zhong, L.; Baptista, S.; Gattoni, R.; Arnold, J.; Flickinger, D.; Stringer, C.; Pachitariu, M.

10.1101/2024.02.25.581990 — neuroscience — Posted on 2024-02-27

598 A molecularly defined NAcSh D1 subtype controls feeding and energy homeostasis

Liu, Y.; Wang, Y.; Zhao, Z.; Xie, G.; Zhang, C.; Chen, R.; Zhang, Y.

10.1101/2023.02.27.530275 — neuroscience — Posted on 2024-02-27

599 Peripheral Neuronal Activation Shapes the Microbiome and Alters Gut Physiology

Griffiths, J. A.; Yoo, B. B.; Thuy-Boun, P.; Cantu, V.; Weldon, K.; Challis, C.; Sweredoski, M. J.; Chan, K. Y.; Thron, T. M.; Sharon, G.; Moradian, A.; Humphrey, G.; Zhu, Q.; Shaffer, J.; Wolan, D. W.; Dorrestein, P.; Knight, R.; Gradinaru, V.; Mazmanian, S.

10.1101/2021.04.12.439539 — physiology — Posted on 2024-02-27

600 A multiprotein signaling complex sustains AKT and mTOR/S6K activity necessary for the survival of cancer cells undergoing stress

Teran, O. Y.; Zanotelli, M. R.; Lin, M.-c. J.; Schmitt, R. R.; Green, K. S.; Rojas, K. S.; Hwang, I. Y.; Cerione, R. A.; Wilson, K. F.

10.1101/2023.01.03.522657 — cancer biology — Posted on 2024-02-27

601 Dysregulation of the p53 pathway provides a therapeutic target in aggressive pediatric sarcomas with stem-like traits

Curylova, L.; Staniczkova Zambo, I.; Neradil, J.; Kyr, M.; Jurackova, N.; Pavlova, S.; Polaskova, K.; Mudry, P.; Sterba, J.; Veselska, R.; Skoda, J.

10.1101/2024.01.17.576012 — cancer biology — Posted on 2024-02-27

602 Evaluating the Utilities of Foundation Models in Single-cell Data Analysis

Liu, T.; Li, K.; Wang, Y.; Li, H.; Zhao, H.

10.1101/2023.09.08.555192 — bioinformatics — Posted on 2024-02-27

603 β-amino acids reduce ternary complex stability and alter the translation elongation mechanism

Cruz Navarrete, F. A.; Griffin, W. C.; Chan, Y.-C.; Martin, M. I.; Alejo, J. L.; Natchiar, S. K.; Knudson, I.; Altman, R. B.; Schepartz, A.; Miller, S. J.; Blanchard, S. C.

10.1101/2024.02.24.581891 — biochemistry — Posted on 2024-02-27

604 Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase dependent mechanism

Gilsbach, B. K.; Ho, F. Y.; Riebenbauer, B.; Zhang, X.; Guaitoli, G.; Kortholt, A.; Gloeckner, C. J.

10.1101/2023.07.31.549909 — biochemistry — Posted on 2024-02-27

605 Emotional state dynamics impacts temporal memory

Wang, J.; Lapate, R. C.

10.1101/2023.07.25.550412 — animal behavior and cognition — Posted on 2024-02-27

606 In silico experiments uncover a novel mechanism underlying mutation rate evolution in sexually reproducing populations

Rozhok, A. I.; Eldredge, N.; DeGregori, J.

10.1101/2021.09.25.461822 — evolutionary biology — Posted on 2024-02-27

607 ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

Hijaze, E.; Gildor, T.; Seidel, R.; Layous, M.; Winter, M.; Bertinetti, L.; Politi, Y.; de-Leon, S. B.-T.

10.1101/2022.12.21.521381 — developmental biology — Posted on 2024-02-27

608 Haploidy-linked cell proliferation defects limit larval growth in Zebrafish

Yaguchi, K.; Saito, D.; Menon, T.; Matsura, A.; Mizutani, T.; Kotani, T.; Nair, S.; Uehara, R.

10.1101/2022.05.12.491746 — developmental biology — Posted on 2024-02-27

609 Mechanotransductive feedback control of endothelial cell motility and vascular morphogenesis

Mason, D. E.; Camacho, P.; Goeckel, M.; Tobin, B. R.; Vega, S. L.; Wu, P.-H.; Johnson, D.; Heo, S.-J.; Wirtz, D.; Burdick, J. A.; Wood, L.; Chow, B. Y.; Stratman, A. N.; Boerckel, J. D.

10.1101/2022.06.15.496293 — cell biology — Posted on 2024-02-27

610 Gene Expression Reactomes Across Species Do Not Correlate with Gene Structural Similarity

Chen, W.; Chai, Y.; Cui, N. Y.; Gopinath, A.; Zhang, D. Y.

10.1101/2024.02.23.581748 — molecular biology — Posted on 2024-02-27

611 Nuclear GAPDH cascade mediates pathological cardiac hypertrophy

Zhang, M.; Kariya, T.; Numata, G.; Sasaki, H.; Sasaki, M.; Ramos, A.; Nakamura, S.; Iwakiri, M.; Koitabashi, N.; Zhu, G.; Tsujimura, T.; Lee, D.-i.; Tristan, C.; Shahani, N.; Tsuchiya, Y.; Jaaro-Peled, H.; Sasano, T.; Slusher, B. S.; Kass, D.; Saitoh, T.; Ishizuka, K.; Sawa, A.; Takimoto, E.

10.1101/844902 — molecular biology — Posted on 2024-02-27

612 Genetic Stability of Mycobacterium smegmatis under the Stress of First-Line Antitubercular Agents: Assessing Mutagenic Potential

Molnar, D.; Suranyi, E. V.; Trombitas, T.; Füzesi, D.; Hirmondo, R.; Toth, J.

10.1101/2024.02.21.581394 — molecular biology — Posted on 2024-02-27

613 HIV-1 Vpr combats the PU.1-driven antiviral response in primary human macrophages.

Virgilio, M. C.; Ramnani, B.; Chen, T.; Disbennett, W. M.; Lubow, J.; Welch, J. D.; Collins, K. L.

10.1101/2023.03.21.533528 — microbiology — Posted on 2024-02-27

614 Inhibitors of the Small Membrane (M) Protein Viroporin Prevent Zika Virus Infection

Brown, E.; Swinscoe, G.; Lefteri, D.; Singh, R.; Moran, A.; Thompson, R.; Maskell, D.; Beaumont, H.; Bentham, M. J.; Donald, C.; Kohl, A.; Macdonald, A.; Ranson, N.; Foster, R.; McKimmie, C. S.; Kalli, A. C.; Griffin, S. C.

10.1101/2021.03.11.435022 — microbiology — Posted on 2024-02-27

615 HippoMaps: Multiscale cartography of the human hippocampal formation

DeKraker, J.; Cabalo, D. G.; Royer, J.; Khan, A. R.; Karat, B.; Benkarim, O.; Rodriguez-Cruces, R.; Frauscher, B.; Pana, R.; Hansen, J. Y.; Misic, B.; Valk, S. L.; Lau, J. C.; Kirschner, M.; Bernasconi, A.; Bernasconi, N.; Muenzing, S.; Axer, M.; Amunts, K.; Evans, A. C.; Bernhardt, B. C.

10.1101/2024.02.23.581734 — neuroscience — Posted on 2024-02-27

616 Electrophysiological signatures of veridical head direction in humans

Griffiths, B. J.; Schreiner, T.; Schaefer, J. K.; Vollmar, C.; Kaufmann, E.; Quach, S.; Remi, J.; Noachtar, S.; Staudigl, T.

10.1101/2023.01.26.525724 — neuroscience — Posted on 2024-02-27

617 Multimodal gradients of human basal forebrain connectivity

Chakraborty, S.; Haast, R. A.; Onuska, K. M.; Kanel, P.; Khan, A. R.; Schmitz, T. W.

10.1101/2023.05.26.541324 — neuroscience — Posted on 2024-02-27

618 Theta cycle dynamics of spatial representations in the lateral septum

Bzymek, K.; Kloosterman, F.

10.1101/2023.07.17.549368 — neuroscience — Posted on 2024-02-27

619 Flexible communication between cell assemblies and 'reader' neurons

Pompili, M. N.; Todorova, R.; Boucly, C. J.; Leroux, E. M.; Wiener, S.; Zugaro, M.

10.1101/2022.09.06.506754 — neuroscience — Posted on 2024-02-27

620 How motivational interviewing shifts food choices and craving-related brain responses to healthier options

Rodrigues, B.; Khalid, I.; Frileux, S.; Flament, B.; Yoldas, Z.; Rampanana, M.; Aubertin, H.; Oppert, J.-M.; Poitou, C.; Rotge, J.-Y.; Fossati, P.; Koban, L.; Schmidt, L.

10.1101/2023.10.13.562241 — neuroscience — Posted on 2024-02-27

621 Dendro-plexing single input spikes by multiple synaptic contacts enriches the computational capabilities of cortical neurons and reduces axonal wiring

Beniaguev, D.; Shapira, S.; Segev, I.; London, M.

10.1101/2022.01.28.478132 — neuroscience — Posted on 2024-02-27

622 Nationwide Inclusive Facilitator Training: Mindsets, Practices and Growth

Codding, D.; Yen, A. H.; Lewis, H.; Johnson-Ojeda, V.; Frey, R. F.; Hokanson, S. C.; Goldberg, B. B.

10.1101/2024.01.08.574770 — scientific communication and education — Posted on 2024-02-27

623 Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

Arabanian, L. S.; Adamsson, J.; Unger, A.; Di Lucrezia, R.; Bergbrede, T.; Ashouri, A.; Larsson, E.; Nussbaumer, P.; Klebl, B. M.; Palmqvist, L.; Gustafsson, C. M.

10.1101/2022.09.23.509145 — cancer biology — Posted on 2024-02-27

624 Using pose estimation and 3D rendered models to study leg-mediated self-righting by lanternflies

Bien, T.; Alexander, B. H.; Li, C.; Goeler-Slough, N.; Hsieh, S. T.; Kane, S. A.

10.1101/2023.02.06.527347 — biophysics — Posted on 2024-02-27

625 Cytometry Masked Autoencoder: An Accurate and Interpretable Automated Immunophenotyper

Kim, J.; Ionita, M.; Lee, M.; McKeague, M. L.; Pattekar, A.; Painter, M. M.; Wagenaar, J.; Truong, V.; Norton, D. T.; Mathew, D.; Nam, Y.; Apostolidis, S. A.; Clendenin, C.; Orzechowski, P.; Jung, S.-H.; Woerner, J.; Ittner, C. A. G.; Turner, A. P.; Esperanza, M.; Dunn, T. G.; Mangalmurti, N. S.; Reilly, J. P.; Meyer, N. J.; Calfee, C. S.; Liu, K. D.; Matthy, M. A.; Swigart, L. B.; Burnham, E. L.; McKeehan, J.; Gandotra, S.; Russel, D. W.; Gibbs, K. W.; Thomas, K. W.; Barot, H.; Greenplate, A. R.; Wherry, E. J.; Kim, D.

10.1101/2024.02.13.580114 — bioinformatics — Posted on 2024-02-27

626 SQUARNA - an RNA secondary structure prediction method based on a greedy stem formation model

Bohdan, D. R.; Nikolaev, G. I.; Bujnicki, J. M.; Baulin, E. F.

10.1101/2023.08.28.555103 — bioinformatics — Posted on 2024-02-27

627 Challenging the Astral mass analyzer - up to 5300 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity.

Bubis, J. A.; Arrey, T. N.; Damoc, E.; Delanghe, B.; Slovakova, J.; Sommer, T. M.; Kagawa, H.; Pichler, P.; Rivron, N. C.; Mechtler, K.; Matzinger, M.

10.1101/2024.02.01.578358 — biochemistry — Posted on 2024-02-27

628 Structural proteomics of a bacterial mega membrane protein complex: FtsH-HflK-HflC

Akkulak, H.; Ince, H. K.; Goc, G.; Lebrilla, C. B.; Kabasakal, B. V.; Ozcan, S.

10.1101/2023.06.07.544024 — biochemistry — Posted on 2024-02-27

629 Evolutionary analysis of gene ages across TADs associates chromatin topology with whole genome duplications

James, C.; Trevisan-Herraz, M.; Juan, D.; Rico, D.

10.1101/2021.06.11.448047 — genomics — Posted on 2024-02-27

630 Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent

Korfmann, K.; Sellinger, T. P. P.; Freund, F.; Fumagalli, M.; Tellier, A.

10.1101/2022.09.28.508873 — genetics — Posted on 2024-02-27

631 Cleave and Rescue gamete killers create conditions for gene drive in plants

Oberhofer, G.; Johnson, M.; Ivy, T.; Antoshechkin, I.; Hay, B.

10.1101/2023.10.13.562303 — genetics — Posted on 2024-02-27

632 A model for the gradual evolution of dioecy and heterogametic sex determination

Lesaffre, T.; Pannell, J. R.; Mullon, C.

10.1101/2023.03.24.534076 — evolutionary biology — Posted on 2024-02-27

633 Analysing biodiversity observation data collected in continuous time: Should we use discrete- or continuous-time occupancy models?

Pautrel, L.; Moulherat, S.; Gimenez, O.; Etienne, M.-P.

10.1101/2023.11.17.567350 — ecology — Posted on 2024-02-27

634 Telling mutualistic and antagonistic ecological networks apart by learning their multiscale structure

Pichon, B.; Le Goff, R.; Morlon, H.; Perez-Lamarque, B.

10.1101/2023.04.04.535603 — ecology — Posted on 2024-02-27

635 Ivermectin resistance in dung beetles exposed for multiple generations

Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.

10.1101/2023.05.08.539900 — ecology — Posted on 2024-02-27

636 Rapid response of fly populations to gene dosage across development and generations

Li, X. C.; Gandara, L.; Ekelof, M.; Richter, K.; Alexandrov, T.; Crocker, J.

10.1101/2022.09.28.509860 — developmental biology — Posted on 2024-02-27

637 Nano-clusters of ligand-activated integrins organize immobile, signalling active, nano-clusters of phosphorylated FAK required for mechanosignalling in focal adhesions

Jain, K.; Minhaj, R. F.; Kanchanawong, P.; Sheetz, M. P.; Changede, R.

10.1101/2024.02.25.581925 — cell biology — Posted on 2024-02-27

638 Quantitative modeling of the emergence of macroscopic grid-like representations

Bin Khalid, I.; Reifenstein, E. T.; Auer, N.; Kunz, L.; Kempter, R.

10.1101/2022.12.20.521210 — neuroscience — Posted on 2024-02-27

639 ENQUIRE RECONSTRUCTS AND EXPANDS CONTEXT-SPECIFIC CO-OCCURRENCE NETWORKS FROM BIOMEDICAL LITERATURE

Musella, L.; Lai, X.; Widmann, M.; Vera Gonzalez, J.

10.1101/2023.09.10.556351 — systems biology — Posted on 2024-02-27

640 Phylogenomics resolves a 100-year-old debate regarding the evolutionary history of caddisflies (Insecta: Trichoptera)

Ge, X.; Peng, L.; Morse, J. C.; Wang, J.; Zang, H.; Yang, L.; Sun, C.; Wang, B.

10.1101/2024.02.26.582007 — zoology — Posted on 2024-02-26

641 Stress pathway outputs are encoded by pH-dependent phase separation of its components.

Didan, Y.; Ghomlaghi, M.; Nguyen, L. K.; Ng, D. C. H.

10.1101/2024.02.24.581896 — systems biology — Posted on 2024-02-26

642 Deep plasma proteomics with data-independent acquisition: A fastlane towards biomarkers identification.

Ward, B.; Pyr dit Ruys, S.; Balligand, J.-L.; Belkhir, L.; Cani, P. D.; Collet, J.-F.; De Greef, J.; Gatto, L.; Haufroid, V.; Jodogne, S.; Kabamba, B.; Lingurski, M.; Yombi, J. C.; Vertommen, D.; Elens, L.

10.1101/2024.02.23.581160 — systems biology — Posted on 2024-02-26

643 Decoding the role of DNA sequence on protein-DNA co-condensation

Singh, R. K.; Swain, P.; Ganji, M.; Choubey, S.

10.1101/2024.02.24.581870 — biophysics — Posted on 2024-02-26

644 Y chromosome sequencing data suggests dual paths of haplogroup N1a1 into Finland

Preussner, A.; Leinonen, J.; Riikonen, J.; Pirinen, M.; Tukiainen, T.

10.1101/2024.02.23.581727 — genetics — Posted on 2024-02-26

645 A global-scale dataset of bat viral detection suggests that pregnancy reduces viral shedding

Eskew, E. A.; Olival, K. J.; Mazet, J. A. K.; Daszak, P.; PREDICT Consortium,

10.1101/2024.02.25.581969 — ecology — Posted on 2024-02-26

646 Dissecting the role of CAR signaling architectures on T cell activation and persistence using pooled screening and single-cell sequencing

Castellanos-Rueda, R.; Wang, K.-L. K.; Forster, J. L.; Driessen, A.; Frank, J. A.; Martinez, M. R.; Reddy, S. T.

10.1101/2024.02.26.582129 — synthetic biology — Posted on 2024-02-26

647 FLIPs: Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy

Miclea, P. S.; Nagy Markova, V.; Sakhi, A.; Bondar, A.; Lazar, J.

10.1101/2024.02.23.581811 — physiology — Posted on 2024-02-26

648 Another fly diuretic hormone: tachykinins increase fluid and ion transport by adult Drosophila melanogaster Malpighian 'renal' tubules

Agard, M. A.; Zandawala, M.; Paluzzi, J.-P. V.

10.1101/2024.02.22.581479 — physiology — Posted on 2024-02-26

649 Unraveling the Complexity of Abdominal Aortic Aneurysm: Multiplexed Imaging Insights into C-Reactive Protein-Related Variations

Kim, E. N.; Seok, H. Y.; Koh, J.; Yang, W.; Lee, G. H.; Choi, W. H.; Lim, J. S.; Ok, Y. J.; Choi, J.-S.; Kim, C. J.; Zhuang, L.; Chang, Y. H.; Oh, S. J.

10.1101/2024.02.22.581315 — pathology — Posted on 2024-02-26

650 Detecting phenotype-specific tumor microenvironment by merging bulk and single cell expression data to spatial transcriptomics

Zhu, W.; Tang, H.; Zeng, T.

10.1101/2024.02.23.581547 — bioinformatics — Posted on 2024-02-26

651 Oxygen affinities of DosT and DosS sensor kinases with implications for hypoxia adaptation in Mycobacterium tuberculosis

Apiche, E. A.; Yee, E.; Damodaran, A. R.; Bhagi-Damodaran, A.

10.1101/2024.02.26.582189 — biochemistry — Posted on 2024-02-26

652 Loss of the APP regulator RHBDL4 preserves memory in an Alzheimer's disease mouse model.

Penalva, Y. C. M.; Paschkowsky, S.; Yang, J.; Recinto, S. J.; Cinkorpumin, J.; Xiao, B.; Nitu, A.; Munter, H. M.; Michalski, B.; Fahnestock, M.; Pastor, W. A.; Bennett, D. A.; Munter, L. M.

10.1101/2024.02.22.579698 — animal behavior and cognition — Posted on 2024-02-26

653 Evaluation of Bayesian Linear Regression Models for Gene Set Prioritization in Complex Diseases

Gholipourshahraki, T.; Bai, Z.; Shrestha, M.; Hjelholt, A. J.; Kjolby, M.; Rohde, P. D.; Sorensen, P.

10.1101/2024.02.23.581718 — genomics — Posted on 2024-02-26

654 The reference genome of an endangered Asteraceae, Deinandra increscens subsp. villosa, endemic to the Central Coast of California

McEvoy, S. L.; Meyer, R. S.; Hasenstab-Lehman, K. E.; Guilliams, C. M.

10.1101/2024.02.25.582000 — genomics — Posted on 2024-02-26

655 Meiotic DSB repair DNA synthesis tracts in Arabidopsis thaliana

Hernandez Sanchez-Rebato, M.; Schubert, V.; White, C. I.

10.1101/2024.02.25.582015 — genetics — Posted on 2024-02-26

656 Thermal plasticity in protective wing pigmentation is modulated by genotype and food availability in an insect model of seasonal polyphenism.

van Bergen, E.; Atencio, G.; Saastamoinen, M.; Beldade, P.

10.1101/2024.02.26.582119 — evolutionary biology — Posted on 2024-02-26

657 Rapid spread of a vertically transmitted symbiont induces drastic shifts in butterfly sex ratio

Miyata, M.; Nomura, M.; Kageyama, D.

10.1101/2024.02.24.581844 — evolutionary biology — Posted on 2024-02-26

658 The sea urchin intestinal microbiome responds dynamically to food intake and contains nitrogen-fixing symbionts

Bengtsson, M. M.; Helgesen, M.; Wang, H.; Fredriksen, S.; Norderhaug, K. M.

10.1101/2024.02.25.581913 — ecology — Posted on 2024-02-26

659 Zebrafish and cellular models of SELENON-Related Myopathy exhibit novel embryonic and metabolic phenotypes

Barraza-Flores, P.; Moaghadaszadeh, B. S.; Lee, W.; Issac, B.; Sung, L.; Hickey, E.; Rockowitz, S.; Sliz, P.; Beggs, A. H.

10.1101/2024.02.26.581979 — molecular biology — Posted on 2024-02-26

660 SREBP-mediated gene expression regulation is essential for the intrinsic fungicide tolerance and antagonism in the fungal biocontrol agent Clonostachys rosea

Piombo, E.; Tzelepis, G.; Ruus, A. G.; Rafiei, V.; Jensen, D. F.; Karlsson, M.; Dubey, M.

10.1101/2024.02.26.582079 — microbiology — Posted on 2024-02-26

661 KoRV-related retroviruses in diverse Australian and African rodent species

Hayward, J. A.; Tachedjian, G.

10.1101/2024.02.25.581998 — microbiology — Posted on 2024-02-26

662 The Chlamydia trachomatis Inc Tri1 interacts with TRAF7 to displace native TRAF7 interacting partners

Herrera, C.; McMahon, E.; Swaney, D. L.; Sherry, J.; Pha, K.; Adams-Boone, K.; Johnson, J.; Krogan, N.; Stevers, M.; Solomon, D.; Elwell, C.; Engel, J.

10.1101/2024.02.26.581999 — microbiology — Posted on 2024-02-26

663 Sand flies and Toscana virus: intra-vector infection dynamics and impact on Phlebotomus perniciosus life-history traits

Laroche, L.; Banuls, A.-L.; Charrel, R.; Fontaine, A.; Ayhan, N.; Prudhomme, J.

10.1101/2024.02.25.582017 — microbiology — Posted on 2024-02-26

664 Population genomics resolves cryptic species of the ecologically flexible genus Laspinema (cyanobacteria)

Dvorak, P.; Skoupy, S.; Jarosova, H.; Palenickova, K.; Stanojkovic, A.

10.1101/2024.02.26.582125 — microbiology — Posted on 2024-02-26

665 MetaWorm: A Complete Model Bridging Brain, Body and Environment of C. elegans

Zhao, M.; Wang, N.; Jiang, X.; Ma, X.; Ma, H.; He, G.; Du, K.; Ma, L.; Huang, T.

10.1101/2024.02.22.581686 — neuroscience — Posted on 2024-02-26

666 Development of rat organoids to study intestinal adaptations after Roux-en-Y Gastric Bypass

Benhaddou, S.; Ribeiro-Parenti, L.; Vaugrente, A.; Willemetz, A.; Gaudichon, C.; Douard, V.; Le Gall, M.; Larraufie, P.

10.1101/2024.02.24.581868 — physiology — Posted on 2024-02-26

667 Optimizing contrast in automated 4D-STEM cryo-tomography

Seifer, S.; Kirchweger, P.; Edel, K. M.; Elbaum, M.

10.1101/2024.02.23.581684 — biophysics — Posted on 2024-02-26

668 Exploring the conformational space of protein-protein complex with transformer-based generative model

Wang, J.; Wang, X.; Chu, Y.; Li, C.; Li, X.; Meng, X.; Fang, Y.; No, K. T.; Mao, J.; Zeng, X.

10.1101/2024.02.24.581708 — bioinformatics — Posted on 2024-02-26

669 Concatenation of segmented viral genomes for reassortment analysis

Ivanova, A. O.; Volchkov, P. Y.; Deviatkin, A. A.

10.1101/2024.02.26.582008 — bioinformatics — Posted on 2024-02-26

670 Decoding Stability and Epistasis in Human Myoglobin by Deep Mutational Scanning and Codon-level Machine Learning

Kueng, C.; Protsenko, O.; Vanella, R.; Nash, M.

10.1101/2024.02.24.581358 — bioengineering — Posted on 2024-02-26

671 Code for Collagen Folding Deciphered

Malcor, J.-D.; Ferruz, N.; Romero-Romero, S.; Dhingra, S.; Sagar, V.; Jalan, A. A.

10.1101/2024.02.24.581883 — biochemistry — Posted on 2024-02-26

672 A Fluorogenic Green Merocyanine-Based Probe to Detect Heparanase-1 Activity

Rabinowitz, Z. M.; Wang, Z.; Liu, J.; Zhang, Y.; Jimenez Ybargollin, A.; Saketkhou, M.; Cui, L.

10.1101/2024.02.25.581963 — biochemistry — Posted on 2024-02-26

673 Perturbations in Risk/Reward Decision Making and Frontal Cortical Catecholamine Regulation Induced by Mild Traumatic Brain Injury

Knapp, C. P.; Papadopoulos, E.; Loweth, J. A.; Raghupathi, R.; Floresco, S. B.; Waterhouse, B. D.; Navarra, R. L.

10.1101/2024.02.22.581581 — animal behavior and cognition — Posted on 2024-02-26

674 Exploring adaptation routes to low temperatures in the Saccharomyces genus

Pinto, J.; Balarezo-Cisneros, L. N.; Delneri, D.

10.1101/2024.02.25.582014 — genetics — Posted on 2024-02-26

675 ADELLE: A global testing method for Trans-eQTL mapping

Akinbiyi, T.; McPeek, M. S.; Abney, M.

10.1101/2024.02.24.581871 — genetics — Posted on 2024-02-26

676 An arch worth revisiting: A study on the feline humeral supracondylar foramen and its evolutionary significance

Byrne, E.; Johnston, R. D.; Kilroy, D.; Bhattacharjee, S.

10.1101/2024.02.25.581957 — evolutionary biology — Posted on 2024-02-26

677 Global variation in the ratio of sapwood to leaf area explained by optimality principles

Xu, H.; Wang, H.; Prentice, I. C.; Harrison, S.; Rowland, L.; Mencuccini, M.; Sanchez-Martinez, P.; He, P.; Wright, I. J.; Sitch, S.; Ye, Q.

10.1101/2024.02.24.581904 — ecology — Posted on 2024-02-26

678 Preference for and resistance to a toxic sulfur volatile opens up a unique niche in Drosophila busckii

Pal Mahadevan, V.; Galagovsky, D.; Knaden, M.; Hansson, B. S.

10.1101/2024.02.24.581869 — ecology — Posted on 2024-02-26

679 Oomycete communities in lowland tropical forest soils vary in abundance and are composed of saprophytes and pathogens of seeds and seedlings of multiple plant species.

Broders, K.; Capador-Barreto, H.; Iriarte, G.; Wright, J.; Baur, M.; Espinosa-Ortega, H.; Spear, E.

10.1101/2024.02.25.580666 — ecology — Posted on 2024-02-26

680 Local ecdysone synthesis in a wounded epithelium sustains developmental delay and promotes regeneration in Drosophila

Terry, D. E.; Schweibenz, C. K.; Moberg, K.

10.1101/2024.02.25.581888 — developmental biology — Posted on 2024-02-26

681 Decoupled degradation and translation enables noise-modulation by poly(A)-tails

Grandi, C.; Emmaneel, M.; Nelissen, F. H. T.; Roosenboom, L. W. M.; Petrova, Y.; Elzokla, O.; Hansen, M. M. K.

10.1101/2024.02.26.582038 — molecular biology — Posted on 2024-02-26

682 High performance TadA-8e derived cytosine and dual base editors with undetectable off-target effects in plants

Fan, T.; Cheng, Y.; Wu, Y.; Liu, S.; Tang, X.; He, Y.; Liao, S.; Zheng, X.; Zhang, T.; Qi, Y.; Zhang, Y.

10.1101/2024.02.25.581917 — molecular biology — Posted on 2024-02-26

683 A novel PSMB8 isoform associated with multiple sclerosis lesions induces P-body formation

Shaw, B.; Williams, J. L.

10.1101/2024.02.26.582162 — molecular biology — Posted on 2024-02-26

684 Molecular regulation of Bna1205ams1 required for male fertility and development of a recessive genic male-sterility system in Brassica napus

Xiao, L.; Zhang, J.; Yu, K.; Yang, X.; Wang, Q.; Jin, H.; Ouyang, Q.; Tian, E.

10.1101/2024.02.25.581914 — molecular biology — Posted on 2024-02-26

685 Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar and Scarif infecting a broad range of host species

Rackow, B.; Rolland, C.; Mohnen, I.; Wittmann, J.; Overmann, J.; Frunzke, J.

10.1101/2024.02.26.582091 — microbiology — Posted on 2024-02-26

686 The energy metabolism of Cupriavidus necator in different trophic conditions

Jahn, M.; Crang, N.; Gynna, A. H.; Kabova, D.; Frielingsdorf, S.; Lenz, O.; Charpentier, E.; Hudson, E. P.

10.1101/2024.02.26.582058 — microbiology — Posted on 2024-02-26

687 Long-term Culturing of Pseudomonas aeruginosa in Static, Minimal Nutrient Medium Results in Increased Pyocyanin Production, Reduced Biofilm Production, and Loss of Motility

Cecil, R. E.; Ornelas, E.; Phan, A.; Yoder-Himes, D. R.

10.1101/2024.02.26.582132 — microbiology — Posted on 2024-02-26

688 Natural products from food sources can alter the spread of AMR plasmids in Enterobacterales

Alav, I.; Pordelkhaki, P.; Rodriguez Navarro, J.; Neo, O.; Kessler, C.; Awodipe, R. J.; Cliffe, P.; Marton, H.; Gibbons, S.; Buckner, M. M. C.

10.1101/2024.02.26.582065 — microbiology — Posted on 2024-02-26

689 Spatial kinetics and immune control of murine cytomegalovirus infection in the salivary glands

Byrne, C. M.; Marquez, A. C.; Cai, B.; Coombs, D.; Gantt, S.

10.1101/2024.02.22.581694 — microbiology — Posted on 2024-02-26

690 Heterologous Prime-Boost with Immunologically Orthogonal Protein Nanoparticles for Peptide Immunofocusing

Bhattacharya, S.; Jenkins, M. C.; Keshavarz-Joud, P.; Bourque, A. R.; White, K.; Barkane, A. M. A.; Bryksin, A. V.; Hernandez, C.; Kopylov, M.; Finn, M. G.

10.1101/2024.02.24.581861 — immunology — Posted on 2024-02-26

691 Modeling gene-environment interactions in Parkinson's Disease: Helicobacter pylori infection of Pink1-/- mice induces CD8 T cell-dependent motor and cognitive dysfunction.

Kazanova, A.; Sung, J.; Oliveira, N. L.; Gavino, C.; Bessaiah, H.; Pei, J.; Burns, L.; Miller, W.; Brouillard-Galipeau, M.; Zhu, L.; Guerra, L. M.; Elemeery, M. N.; Recinto, S. J.; MacDonald, A.; Lanoix, J.; Thibault, P.; McBride, H. M.; Desjardins, M.; Stratton, J. A.; Labrecque, N.; Gruenheid, S.

10.1101/2024.02.25.580545 — immunology — Posted on 2024-02-26

692 Odor-induced persistent neural activity in associativeencoding in humans

Tarrida, J.; Fuentemilla, L.; Marco-Pallares, J.; Moreno, M.; Panyella, D.; Vidal, J.

10.1101/2024.02.23.581728 — neuroscience — Posted on 2024-02-26

693 Developmentally stable representations of naturalistic image structure in macaque visual cortex

Lee, G. M.; Rodriguez Deliz, C. L.; Bushnell, B. N.; Majaj, N. J.; Movshon, J. A.; Kiorpes, L.

10.1101/2024.02.24.581889 — neuroscience — Posted on 2024-02-26

694 Career Navigator: An online platform to streamline professional development and career education for graduate bioscientists

Rudlaff, R.; Adhikary, U. J.; Khairani, C.; Emmans, D. S.; Gutlerner, J. L.; Heustis, R. J.

10.1101/2024.02.22.580689 — scientific communication and education — Posted on 2024-02-26

695 The physiology of bud dormancy and cell cycle status in grapevine

Hermawaty, D.; Clode, P.; Considine, J. A.; Signorelli, S.; Considine, M. J.

10.1101/2024.02.22.581692 — plant biology — Posted on 2024-02-26

696 Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase

Danda, M.; Klimesova, A.; Kuskova, K.; Dostalkova, A.; Pagacova, A.; Prchal, J.; Kapisheva, M.; Ruml, T.; Rumlova, M.

10.1101/2024.02.24.581855 — biochemistry — Posted on 2024-02-26

697 What Causes Persistent Neural Activity? Part I

Verma, V.

10.1101/2024.02.19.581018 — neuroscience — Posted on 2024-02-26

698 Friction-induced budding of a cancer cell monolayer

Dedenon, M.; Barbazan, J.; Perez Gonzalez, C.; Vignjevic, D.; Sens, P.

10.1101/2024.02.26.582028 — biophysics — Posted on 2024-02-26

699 Machine learning identifies cell-free DNA 5-hydroxymethylation biomarkers that detect occult colorectal cancer in PLCO Screening Trial subjects

West-Szymanski, D. C.; Zhang, Z.; Cui, X.-L.; Kowitwanich, K.; Gao, L.; Deng, Z.; Dougherty, U.; Williams, C.; Merkle, S.; Moore, M.; He, C.; Bissonnette, M.; Zhang, W.

10.1101/2024.02.25.581955 — genomics — Posted on 2024-02-26

700 TASOR expression in naive embryonic stem cells safeguards their developmental potential

Pinzon-Arteaga, C. A.; O'Hara, R.; Mazzagati, A.; Ballard, E.; Hu, Y.; Pan, A.; Schmitz, D. A.; Wei, Y.; Sakurai, M.; Ly, P.; Banaszynski, L.; Wu, J.

10.1101/2024.02.25.581951 — developmental biology — Posted on 2024-02-26

701 The Role of Nde1 Phosphorylation in Interkinetic Nuclear Migration and Schizophrenia

Doobin, D. J.; Helmer, P.; carabalona, A.; Bertipaglia, C.; Vallee, R. B.

10.1101/2024.02.25.581986 — developmental biology — Posted on 2024-02-26

702 Spatial patterning of the epigenome during vertebrate gastrulation

Azambuja, A. P.; Rothstein, M.; Kanno, T. Y.; Simoes-Costa, M.

10.1101/2024.02.26.581880 — developmental biology — Posted on 2024-02-26

703 Mechanical confinement induces ferroptosis through mitochondrial dysfunction

Zhou, F.; Kang, C.; Li, J.; Yang, A.; Ju, R. J.; Sun, Y.; Liang, L.; Hu, X.; Stehbens, S. J.; Wu, C.

10.1101/2024.02.23.581510 — cell biology — Posted on 2024-02-26

704 PTEN and the PTEN-like phosphatase CnrN have both distinct and overlapping roles in a Dictyostelium chemorepulsion pathway

Consalvo, K. M.; Rijal, R.; Beruvides, S.; Mitchell, R.; Beauchemin, K.; Collins, D.; Scoggin, J.; Scott, J.; Gomer, R.

10.1101/2024.02.23.581751 — cell biology — Posted on 2024-02-26

705 Sleep pressure accumulates in a voltage-gated lipid peroxidation memory

Rorsman, H. O.; Müller, M. A.; Liu, P. Z.; Sanchez, L. G.; Kempf, A.; Gerbig, S.; Spengler, B.; Miesenboeck, G.

10.1101/2024.02.25.581768 — neuroscience — Posted on 2024-02-26

706 Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation

Bellotti, P.; Ladd, Z.; Leroy, V.; Su, G.; Sharma, S.; Hartman, J.; Krebs, J.; Viscardi, C.; Maile, R.; Moldawer, L.; Efron, P. A.; Sharma, A. K.; Upchurch, G. R.

10.1101/2024.02.23.581672 — immunology — Posted on 2024-02-26

707 KSR1 regulates small-cell lung carcinoma tumor initiation and therapy resistance

Chatterjee, D.; Svoboda, R. A.; Huisman, D. H.; Vieira, H. M.; Rao, C.; Askew, J. W.; Fisher, K. W.; Lewis, R. E.

10.1101/2024.02.23.581815 — cancer biology — Posted on 2024-02-26

708 Pre-bound State Discovered in the Unbinding Pathway of Fluorinated Variants of the Trypsin-BPTI Complex Using Random AccelerationMolecular Dynamics Simulations

Wehrhan, L.; Keller, B. G.

10.1101/2024.02.22.581541 — biophysics — Posted on 2024-02-26

709 The importance of stereochemistry in the disorder-order continuum of protein-protein interactions

Newcombe, E. A.; Due, A. D.; Sottini, A.; Fernandes, C. B.; Staby, L.; Delaforge, E.; Bartling, C. R. O.; Brakti, I.; Bugge, K.; Schuler, B.; Skriver, K.; Olsen, J. G.; Kragelund, B. B.

10.1101/2024.02.23.581681 — biophysics — Posted on 2024-02-26

710 On the relationship between concentration buffering and noise reduction in phase separating systems

Zechner, C.; Julicher, F.

10.1101/2024.02.26.579621 — biophysics — Posted on 2024-02-26

711 Chlorpromazine inhibits EAG1 channels by altering the coupling between the PAS, CNBH and pore domains

Ghorbani, M.; Wang, Z.-J.; Chen, X.; Tiwari, P. B.; Klauda, J. B.; Brelidze, T. I. I.

10.1101/2024.02.23.581826 — biophysics — Posted on 2024-02-26

712 Revolutionizing GPCR-Ligand Predictions: DeepGPCR with experimental Validation for High-Precision Drug Discovery

Zhang, H.; Fan, H.; Wang, J.; Hou, T.; Saravanan, K. M.; Xia, W.; Kan, H. W.; Li, J.; Zhang, J. Z. H.; xinmiao, L.; Chen, Y.

10.1101/2024.02.25.581988 — bioinformatics — Posted on 2024-02-26

713 Advancing age grading techniques for Glossina morsitans morsitans, vectors of African trypanosomiasis, through mid-infrared spectroscopy and machine learning

Betancourth, M. P.; Gomez-Uribarri, I. C.; Mondragon-Shem, K.; Babayan, S. A.; Baldini, F.; Haines, L. R.

10.1101/2024.02.19.579508 — biochemistry — Posted on 2024-02-26

714 WITHDRAWN: Oligomerization of the antimalarial drug target PfATP4 is essential for parasite survival

Ramanathan, A. A.; Morrisey, J. M.; Daly, T. M.; Bergman, L. W.; Mather, M. W.; Vaidya, A. B.

10.1101/2019.12.12.874826 — biochemistry — Posted on 2024-02-26

715 TIMAHAC: Streamlined Tandem IMAC-HILIC Workflow for Simultaneous and High-Throughput Plant Phosphoproteomics and N-glycoproteomics

Chen, C.-W.; Lin, P.-Y.; Lai, Y.-M.; Lin, M.-H.; Lin, S.-Y.; Hsu, C.-C.

10.1101/2024.02.26.582001 — biochemistry — Posted on 2024-02-26

716 Structural analysis and conformational dynamics of a holo-adhesion GPCR reveal interplay between extracellular and transmembrane domains

Kordon, S. P.; Cechova, K.; Bandekar, S. J.; Leon, K.; Dutka, P.; Siffer, G.; Kossiakoff, A. A.; Vafabakhsh, R.; Arac, D.

10.1101/2024.02.25.581807 — biochemistry — Posted on 2024-02-26

717 Constraining models of dominance for nonsynonymous mutations in the human genome

Kyriazis, C. C.; Lohmueller, K. E.

10.1101/2024.02.25.582010 — genetics — Posted on 2024-02-26

718 A critical reexamination of recovered SARS-CoV-2 sequencing data

Debarre, F.; Hensel, Z.

10.1101/2024.02.15.580500 — evolutionary biology — Posted on 2024-02-26

719 Mitotic Block and Epigenetic Repression Underlie Neurodevelopmental Defects and Neurobehavioral Deficits in Congenital Heart Disease

Gabriel, G. C.; Yagi, H.; Tan, T.; Bais, A. S.; Glennon, B.; Stapleton, M. C.; Huang, L.; Reynolds, W. T.; Shaffer, M. G.; Ganapathiraju, M.; Simon, D.; Panigrahy, A.; Wu, Y. L.; Lo, C. W.

10.1101/2023.11.05.565716 — developmental biology — Posted on 2024-02-26

720 Promoter motifs facilitate as well as impede the emergence and evolution of gene expression

Fuqua, T.; Sun, Y.; Wagner, A.

10.1101/2024.02.26.581924 — evolutionary biology — Posted on 2024-02-26

721 Nano-clusters of ligand-activated integrins organize immobile, signalling active, nano-clusters of phosphorylated FAK required for mechanosignalling in focal adhesions

Changede, R.; Jain, K.; Minhaj, R. F.; Kanchanawong, P.; Sheetz, M. P.

10.1101/2024.02.25.581925 — cell biology — Posted on 2024-02-26

722 Brain-heart dynamics during emotional processing under uncertain conditions: An index of depression risk

Chan, H.-L.; Kanayama, N.; Mizuochi, R.; Yamawaki, S.; Machizawa, M. G.

10.1101/2021.12.06.471520 — neuroscience — Posted on 2024-02-26

723 Molecular density-accelerated binding-site maturation underlies CENP-T-dependent kinetochore assembly

Tarasovetc, E. V.; Sissoko, G. B.; Mukhina, A. S.; Maiorov, A.; Ataullakhanov, F. I.; Cheeseman, I. M.; Grishchuk, E. L.

10.1101/2024.02.25.581584 — biophysics — Posted on 2024-02-26

724 Enhancement of colorectal cancer therapy through interruption of the HSF1-HSP90 axis by p53 activation or cell cycle inhibition

Isermann, T.; Schneider, K. L.; Wegwitz, F.; De Oliveira, T.; Conradi, L.-C.; Volk, V.; Feuerhake, F.; Papke, B.; Stintzing, S.; Mundt, B.; Kuehnel, F.; Moll, U. M.; Schulz-Heddergott, R.

10.1101/2024.02.22.581507 — cancer biology — Posted on 2024-02-26

725 High-throughput screening for Cushing's disease: therapeutic potential of thiostrepton via cell cycle regulation

Hakata, T.; Yamauchi, I.; Kosugi, D.; Sugawa, T.; Fujita, H.; Okamoto, K.; Ueda, Y.; Fujii, T.; Taura, D.; Inagaki, N.

10.1101/2024.02.22.581351 — cell biology — Posted on 2024-02-26

726 Individual-specific associations between behavioral events and song notes shape budgerigar vocal sequences

Wewhare, N.; Krishnan, A.

10.1101/2024.02.25.581929 — animal behavior and cognition — Posted on 2024-02-26

727 Complete chromosome 21 centromere sequences from a Down syndrome family reveal size asymmetry and differences in kinetochore attachment

Mastrorosa, F. K.; Rozanski, A. N.; Harvey, W. T.; Knuth, J.; Garcia, G.; Munson, K. M.; Hoekzema, K.; Logsdon, G. A.; Eichler, E. E.

10.1101/2024.02.25.581464 — genomics — Posted on 2024-02-26

728 The evolution of reduced facilitation in a four-species bacterial community

Piccardi, P.; Ulrich, E.; Garcia-Garcera, M.; Di Martino, R.; Testa, S. E. A.; Mitri, S.

10.1101/2024.02.22.581583 — evolutionary biology — Posted on 2024-02-26

729 Impacts of a prolonged marine heatwave and chronic local human disturbance on juvenile coral assemblages

Tietjen, K. L.; Perks, N. F.; O'Brien, N. C.; Baum, J. K.

10.1101/2024.02.23.581720 — ecology — Posted on 2024-02-26

730 Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1

Oh, W.-J.; Kim, N.; Li, Y.; Yu, R.; Kwon, H.-S.; Song, A.; Jun, M.-H.; Jeong, J.-Y.; Lee, J. H.; Lim, H.-H.; Kim, M.-J.; Kim, J.-W.

10.1101/2022.05.03.490499 — developmental biology — Posted on 2024-02-26

731 Oxytocin and shared intentionality drive variation in cooperation in children

McClung, J.; Triki, Z.; Lancheros Pompeyo, M.; Fassier, R.; Emery, Y.; Bangerter, A.; Clement, F.; Bshary, R.

10.1101/2024.02.25.581910 — developmental biology — Posted on 2024-02-26

732 Rebalancing the motor circuit restores movement in a Caenorhabditis elegans model for TDP-43-toxicity

Koopman, M.; Gungordu, L.; Janssen, L.; Seinstra, R. I.; Richmond, J. E. X.; Okerlund, N.; Wardenaar, R.; Islam, P.; Brown, A. E. X.; Jorgensen, E. M.; Nollen, E. A. A.

10.1101/2023.10.24.563563 — cell biology — Posted on 2024-02-26

733 Characterization of the microbiome of Aedes albopictus populations in different habitats from Spain and Sao Tome: implications for vector control.

Melo, T. d.; Sousa, C. A.; Delacour, S.; Bravo-Barriga, D.; Seixas, G.

10.1101/2024.02.24.581876 — molecular biology — Posted on 2024-02-26

734 ROS-induced translational regulation--through spatiotemporal differences in codon recognition--is a key driver of brown adipogenesis

Ip, J. Y.; Wijaya, I.; Lee, L. T.; Lim, Y.; Teoh, D. E.-J.; Chan, C. S. C.; Cui, L.; Begley, T. J.; Dedon, P. C.; Guo, H.

10.1101/2023.12.22.572954 — molecular biology — Posted on 2024-02-26

735 Enhancing Recovery from Gut Microbiome Dysbiosis and Alleviating DSS-Induced Colitis in Mice with a Consortium of Rare Short-Chain Fatty Acid-Producing Bacteria

Ambat, A.; Antony, L.; Maji, A.; Ghimire, S.; Mattiello, S.; Kashyap, P.; More, S.; Sebastian, V.; Scaria, J.

10.1101/2023.09.11.556543 — microbiology — Posted on 2024-02-26

736 Co-inoculation with novel nodule-inhabiting bacteria reduces the benefits of legume-rhizobium symbiosis

Kosmopoulos, J. C.; Batstone-Doyle, R. T.; Heath, K. D.

10.1101/2023.11.15.567292 — microbiology — Posted on 2024-02-26

737 Resident Synovial Macrophages in Synovial Fluid: Implications for Immunoregulation in Infectious and Inflammatory Arthritis

Cyndari, K. I.; Scorza, B. M. I.; Zacharias, Z. R.; Strand, L.; Mahachi, K.; Oviedo, J. M.; Gibbs, L.; Pessoa-Pereira, D.; Ausdal, G.; Hendricks, D.; Yahashiri, R.; Elkins, J. M.; Gulbrandsen, T.; Peterson, A. R.; Willey, M. C.; Fairfax, K. C.; Petersen, C. A. A.

10.1101/2023.09.29.560183 — immunology — Posted on 2024-02-26

738 Age-Related Differences in Affective Behaviors in Mice: Possible Role of Prefrontal Cortical-Hippocampal Functional Connectivity and Metabolomic Profiles

Febo, M.; Mahar, R.; Rodriguez, N. A.; Buraima, J.; Pompilus, M.; Pinto, A. M.; Grudny, M. M.; Bruijnzeel, A.; Merritt, M.

10.1101/2023.11.13.566691 — neuroscience — Posted on 2024-02-26

739 A Systematic Review and Meta-analysis on the Transcriptomic Signatures in Alcohol Use Disorder

Friske, M. M.; Torrico, E. C.; Haas, M. J. W.; Borruto, A. M.; Giannone, F.; Hade, A.-C.; Gao, L.; Yu, Y.; Sutherland, G. T.; Hitzemann, R. J.; Philips, M.-A.; Fei, S. S.; Mayfield, R. D.; Sommer, W. H.; Spanagel, R.

10.1101/2022.12.19.521027 — neuroscience — Posted on 2024-02-26

740 Hypoxia disrupts circadian rhythms in astrocytes and causes synapse engulfment defects

Li, L.; Choi, J.; Shin, C. H.; Htun, S.; Mestan, S.; Voss, A.; Shadrach, J. L.; Puno, A.; Nagar, D.; Ramirez, N.; Rojo, D.; Lee, S. H.; Gibson, E. M.; Kaltschmidt, J. A.; Sloan, S. A.; Chung, W.-S.; Pasca, A. M.

10.1101/2024.02.22.581651 — neuroscience — Posted on 2024-02-26

741 Monkeys engage in visual simulation to solve complex problems

Ahuja, A.; Yusif Rodriguez, N.; Ashok, A. K.; Serre, T.; Desrochers, T.; Sheinberg, D.

10.1101/2024.02.21.581495 — neuroscience — Posted on 2024-02-26

742 Light-exercise-induced dopaminergic and noradrenergic stimulation in the dorsal hippocampus: using a rat physiological exercise model

Hiraga, T.; Hata, T.; Soya, S.; Shimoda, R.; Takahashi, K.; Soya, M.; Inoue, K.; Johansen, J. P.; Okamoto, M.; Soya, H.

10.1101/2023.06.19.545490 — neuroscience — Posted on 2024-02-26

743 Identifying Neural Correlates of Balance Deficits in Traumatic Brain Injury Using Partial Least Squares Correlation (PLSC) Analysis

Shenoy Handiru, V.; Selvan Suviseshamuthu, E.; Saleh, S.; Su, H.; Yue, G. H.; Allexandre, D.

10.1101/2022.05.15.491997 — neuroscience — Posted on 2024-02-26

744 Predictive coding for natural vocal signals in the songbird auditory forebrain

Rudraraju, S.; Theilman, B. H.; Turvey, M. E.; Gentner, T. Q.

10.1101/2024.02.25.581987 — neuroscience — Posted on 2024-02-26

745 PRENATAL STRESS MODIFIES SPATIAL COGNITION IN MICE: EFFECTS OF AGE AND SEX.

McCarthy, M.; Buck, T. G.; Sodhi, M.

10.1101/2024.02.23.581828 — neuroscience — Posted on 2024-02-26

746 Meta-Analysis of Public RNA Sequencing Data of Abscisic Acid-Related Abiotic Stresses in Arabidopsis thaliana

Shintani, M.; Tamura, K.; Bono, H.

10.1101/2023.04.17.537107 — plant biology — Posted on 2024-02-26

747 A converged ubiquitin-proteasome pathway for the degradation of TOC and TOM tail-anchored receptors

Yang, M.; Chen, S.; Lim, S.-L.; Yang, L.; Zhong, J. Y.; Chan, K. C.; Zhao, Z.; Wong, K.-B.; Wang, J.; Lim, B. L.

10.1101/2023.01.07.523072 — plant biology — Posted on 2024-02-26

748 Genetic diversity within a tree and alternative indexes for different evolutionary effects

Iwasa, Y.; Tomimoto, S.; Satake, A.

10.1101/2024.02.24.581556 — genetics — Posted on 2024-02-25

749 A pan-tissue, pan-disease compendium of human orphan genes

Singh, U.; Haltom, J.; Guarnieri, J.; Li, J.; Seetharam, A.; Beheshti, A.; Aronow, B.; Wurtele, E. S.

10.1101/2024.02.21.581488 — evolutionary biology — Posted on 2024-02-26

750 Improved potential analysis for inadequate ecological data

Arani, B. M. S.; van Nes, E. H.; Scheffer, M.

10.1101/2024.02.25.581934 — ecology — Posted on 2024-02-25

751 Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice

Novais, E. J.; Ottone, O. K.; Brown, E. V.; Madhu, V.; Tran, V. A.; Dighe, A. S.; Solga, M. D.; Manchel, A.; Lepore, A. C.; Risbud, M. V.

10.1101/2024.02.23.581794 — cell biology — Posted on 2024-02-26

752 Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.

Chartampila, E.; Elayouby, K. S.; Leary, P.; LaFrancois, J. J.; Alcantara-Gonzalez, D.; Jain, S.; Gerencer, K.; Botterill, J. J.; Ginsberg, S. D.; Scharfman, H.

10.1101/2023.05.12.540428 — neuroscience — Posted on 2024-02-26

753 Asynchronous abundance fluctuations can drive giant genotype frequency fluctuations

Ascensao, J. A.; Lok, K.; Hallatschek, O.

10.1101/2024.02.23.581776 — evolutionary biology — Posted on 2024-02-25

754 Mechanistic dissection of the CHD4 enhancers reveals cooperative functions among the homotypic ZNF410 clustered motifs

Xu, S.; Ren, R.; Peng, C.; Lu, H.; Ly, L. C.; Crossley, M.; Xu, B.; Cheng, X.; Blobel, G. A.; Lan, X.

10.1101/2024.02.24.581901 — molecular biology — Posted on 2024-02-25

755 Silicon-rhodamine functionalized evocalcet probes (EvoSiR) potently and selectively label calcium sensing receptors (CaSR) in vitro, in vivo and ex vivo

Batora, D.; Fischer, J. P.; Kaderli, R. M.; Varga, M.; Lochner, M.; Gertsch, J.

10.1101/2024.02.22.581561 — pharmacology and toxicology — Posted on 2024-02-25

756 Metabolic reprogramming of hypoxic tumour-associated macrophages through CSF-1R targeting favours treatment efficiency in colorectal cancers

Gharzeddine, K.; Gonzales Pietro, C.; Malier, M.; Hennot, C.; Grespan, R.; Yamaryo, Y.; Botte, C.; Thomas, F.; Laverriere, M. H.; Girard, E.; Roth, G.; MILLET, A.

10.1101/2024.02.22.581558 — immunology — Posted on 2024-02-25

757 Intervertebral disc cells from human back pain subjects exhibit TNFR1-mediated senescence and lack TNFR2-modulated repair capacity

Gansau, J.; Grossi, E.; Rodriguez, L.; Wang, M.; Laudier, D.; Chaudhary, S.; Hecht, A.; Fu, W.; Sebra, R.; Liu, C.; Iatridis, J. C.

10.1101/2024.02.22.581620 — bioengineering — Posted on 2024-02-25

758 Exploring Arylidene-Indolinone Ligands of Autophagy Proteins LC3B and GABARAP

Leveille, A. N.; Brown, H.; Schwarzrock, T.; True, B.; Plasencia, J.; Neudecker, P.; Üffing, A.; Weiergraber, O. H.; Willbold, D.; Kritzer, J.

10.1101/2024.02.25.581879 — biochemistry — Posted on 2024-02-25

759 β-amino acids reduce ternary complex stability and alter the translation elongation mechanism

Cruz Navarrete, F. A.; Griffin, W. C.; Chan, Y.-C.; Martin, M. I.; Alejo, J. L.; Natchiar, S. K.; Knudson, I.; Altman, R. B.; Schepartz, A.; Miller, S. J.; Blanchard, S. C.

10.1101/2024.02.24.581891 — biochemistry — Posted on 2024-02-25

760 Simultaneous circulation and coinfection of Dengue clades and serotypes in Southern Brazil

Bermann, T.; Baethgen, L. F.; Gregianini, T. S.; Godinho, F. M.; Barcellos, R. B.; Ruivo, A. P.; Bauermann, M.; Selayaran, T. M.; Machado, F.; Schroder, J. A.; Mollmann, E. B.; Martiny, F. L.; Lagranha, V. L.; de Oliveira, L. F. V.; da Veiga, A. B. G.; Zolet, A. C. T.; Wallau, G. L.; Salvato, R. S.

10.1101/2024.02.24.581892 — genomics — Posted on 2024-02-25

761 Evaluation of Bayesian Linear Regression Derived Gene Set Test Methods

Bai, Z.; Gholipourshahraki, T.; Shrestha, M.; Hjelholt, A.; Kjolby, M.; Rohde, P. D.; Sorensen, P.

10.1101/2024.02.23.581726 — genomics — Posted on 2024-02-25

762 Efficient 3'-end tailing of RNA with modified adenosine for nanopore direct total RNA sequencing

Yuan, Y.; Arneson, R.; Burke, E.; Apostle, A.

10.1101/2024.02.24.581884 — genomics — Posted on 2024-02-25

763 The Origins of ATP Dependence in Biological Nitrogen Fixation

Harris, D.; Rucker, H.; Garcia, A.; Yang, Z.-Y.; Chang, S.; Feinsilber, H.; Kacar, B.; Seefeldt, L.

10.1101/2024.02.22.581614 — evolutionary biology — Posted on 2024-02-25

764 mTOR controls growth and internal architecture of human breast cancer spheroids

Hoette, K.; Fischer, S.; Schmitz, A.; Koch, M.; Saeifar, S.; Stelzer, E.; Pampaloni, F.

10.1101/2024.02.24.580871 — cell biology — Posted on 2024-02-25

765 Stabilization of Integrator/INTAC by the small but versatile DSS1 protein

Xu, C.; Zhou, Q.-X.; Zheng, H.; Song, A.; Zhao, W.-Y.; Xiong, Y.; Huang, Z.; Xu, Y.; Cheng, J.; Chen, F. X.

10.1101/2024.02.25.581915 — molecular biology — Posted on 2024-02-25

766 Limited transmission of microbial species among coral reef fishes from the Great Barrier Reef, Australia

Costa, V. A.; Bellwood, D. R.; Mifsud, J. C.; Geoghegan, J. L.; Harvey, E.; Holmes, E. C.

10.1101/2024.02.24.581894 — microbiology — Posted on 2024-02-25

767 Arp2/3 complex-dependent actin regulation protects the survival of tissue-resident mast cells

Kaltenbach, L.; Mihlan, M.; Ulferts, S.; Müsken, M.; Glaser, K. M.; Mittler, G.; Babina, M.; Innocenti, M.; Grosse, R.; Stradal, T. E. B.; Lämmermann, T.

10.1101/2024.02.23.581763 — immunology — Posted on 2024-02-25

768 Identification of Alpha-Gal conjugated Lipids in Saliva of Lone-Star Tick (Amblyomma americanum)

Sharma, S. R.; Hussain, S.; Choudhary, S. K.; Commins, S. P.; Karim, S.

10.1101/2024.02.22.581476 — immunology — Posted on 2024-02-25

769 Heterozygosity for Crohn's Disease Risk Allele of ATG16L1 Protects against Bacterial Infection

Yao, X.; Rudensky, E.; Martin, P. K.; Zwack, E. E.; He, Z.; Furtado, G. C.; Lira, S. A.; Torres, V. J.; Shopsin, B.; Cadwell, K.

10.1101/2024.02.22.581423 — immunology — Posted on 2024-02-25

770 RinRK1 Promotes Accumulation of Nod Factor Receptors in Nanodomain-like structures at the tip of infected root hairs

Zhou, N.; Li, X.; Zheng, Z.; Liu, J.; Downie, A.; Xie, F.

10.1101/2024.02.23.581682 — plant biology — Posted on 2024-02-25

771 Engineering oncogenic hotspot mutations on SF3B1 via CRISPR-directed PRECIS mutagenesis

Fernandez, M.; Jia, Q.; Yu, L.; Wang, X.; Hart, K.; Jia, Z.; Lin, R.-J.; Wang, L.

10.1101/2024.02.23.581842 — cancer biology — Posted on 2024-02-25

772 RNA-binding tunes the conformational plasticity and intradomain stability of TDP-43 tandem RNA recognition motifs

Ozguney, B.; Mohanty, P.; Mittal, J.

10.1101/2024.02.25.581941 — biophysics — Posted on 2024-02-25

773 Influenza A Viral Burst Size from Thousands of Infected Single Cells Using Droplet Quantitative PCR (dqPCR)

Zath, G. K.; Thomas, M. M.; Loveday, E. K.; Bikos, D. A.; Sanche, S.; Ke, R.; brooke, c.; Chang, C. B.

10.1101/2024.02.23.581786 — bioengineering — Posted on 2024-02-25

774 Thg1 family 3'-5' RNA polymerases as tools for targeted RNA synthesis

Jayasinghe, M. I.; Patel, K. J.; Jackman, J. E.

10.1101/2024.02.24.581873 — biochemistry — Posted on 2024-02-25

775 Boosting the Sensitivity of Quantitative Single-Cell Proteomics with Activated Ion-Tandem Mass Tags (AI-TMT)

Peters-Clarke, T.; Liang, Y.; Mertz, K. L.; Lee, K. W.; Westphall, M. S.; Hinkle, J. D.; McAlister, G. C.; Syka, J. E. P.; Kelly, R. T.; Coon, J.

10.1101/2024.02.24.581874 — biochemistry — Posted on 2024-02-25

776 Characterisation of mesenchymal stromal cells in the skin of Atlantic salmon

Ruiz-Daniels, R.; J Salisbury, S.; Sveen, L.; S Taylor, R.; Vaadal, M.; Tengs, T.; Monaghan, S.; R Villamayor, P.; Ballantyne, M.; Penaloza, C.; D Fast, M.; E Bron, J.; D Houston, R.; Robinson, N.; Robledo, D.

10.1101/2024.02.23.581759 — genomics — Posted on 2024-02-25

777 Taxonomic distribution of SbmA/BacA and BacA-like antimicrobial peptide transporters suggests independent recruitment and convergent evolution in host-microbe interactions

Smith, N. T.; Boukherissa, A.; Antaya, K.; Howe, G. W.; Rodriguez de la Vega, R. C.; Shykoff, J. A.; Alunni, B.; diCenzo, G. C.

10.1101/2024.02.25.581009 — microbiology — Posted on 2024-02-25

778 Extracellular chemosymbiont populations in a shallow-water thyasirid clam potentially shaped by priority effect

Li, M.; Li, Y.; Mao, S.; Liu, X.; Wang, H.; Chen, C.; Liu, X.; Zhuang, G.-C.; Zhang, W.; Sun, J.

10.1101/2024.02.25.581922 — microbiology — Posted on 2024-02-25

779 EmbB and EmbC Regulate the Sensitivity of Mycobacterium abscessus to Echinomycin

He, J.; Gao, Y.; Wang, J.; Hameed, H. M. A.; Wang, S.; Fang, C.; Tian, X.; Zhang, J.; Han, X.; Ju, Y.; Tan, Y.; Ma, J.; Ju, J.; Hu, J.; Liu, J.; Zhang, T.

10.1101/2024.02.25.578291 — microbiology — Posted on 2024-02-25

780 Pandemic Risk Assessment for a Swine Influenza A Virus in Comparative Human Substrates

Padykula, I.; Damodaran, L.; Young, K. T.; Krunkosky, M.; Griffin, E. F.; North, J. F.; Neasham, P. J.; Pleiasis, V. C.; Siepker, C. L.; Stanton, J. B.; Howerth, E. W.; Bahl, J.; Kyriakis, C. S.; Tompkins, S. M.

10.1101/2024.02.24.581872 — microbiology — Posted on 2024-02-25

781 AI-driven Classification of Cancer-Associated Fibroblasts Using Morphodynamic and Motile Features

Kang, M.; Min, C.; Devarasou, S.; Shin, J. H.

10.1101/2024.02.22.581611 — cancer biology — Posted on 2024-02-25

782 ASTROGLIOSIS AND NEUROINFLAMMATION UNDERLIE SCOLIOSIS UPON CILIA DYSFUNCTION

Djebar, M.; Anselme, I.; Pezeron, G.; Bardet, P.-L.; Cantaut-Belarif, Y.; Eschstruth, A.; Lopez-Santos, D.; Le Ribeuz, H.; Jenett, A.; Khoury, H.; Veziers, J.; Parmentier, C.; Hirschler, A.; Carapito, C.; Bachmann-Gagescu, R.; Schneider-Maunoury, S.; Vesque, C.

10.1101/2024.02.22.581530 — developmental biology — Posted on 2024-02-25

783 Enterovirus A71 adaptation to heparan sulfate comes with capsid stability tradeoff

Tee, H. K.; Mathez, G.; Cagno, V.; Antanasijevic, A.; Clement, S.; Tapparel, C.

10.1101/2024.02.23.581741 — microbiology — Posted on 2024-02-25

784 Pathologic α-Synuclein-NOD2 Interaction and RIPK2 Activation Drives Microglia-Induced Neuroinflammation in Parkinson's Disease

Ko, H.; Dawson, T. M.; Seo, B. A.; Kwon, S.-H.; Kim, D.; Kim, H.-B.; Ma, S.-X.; Gadhave, K.; Burgess, N.; Mao, X.; Rosenthal, L. S.; Redding-Ochoa, J.; Troncoso, J. C.; Lee, S.; Dawson, V. L.

10.1101/2024.02.19.580982 — neuroscience — Posted on 2024-02-25

785 Mitochondrial origins of the pressure to sleep

Sarnataro, R.; Velasco, C. D.; Monaco, N.; Kempf, A.; Miesenboeck, G.

10.1101/2024.02.23.581770 — neuroscience — Posted on 2024-02-25

786 Fluid Shear Stress-Induced Changes in Megalin Trafficking Enhance Endocytic Capacity in Proximal Tubule Cells

Lackner, E. M.; Cowan, I. A.; Long, K. R.; Weisz, O. A.; Shipman, K. E.

10.1101/2024.02.22.581213 — physiology — Posted on 2024-02-25

787 Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

Chougoni, K. K.; Neely, V.; Ding, B.; Oduah, E.; Lam, V.; Hu, B.; Koblinski, J. E.; Windle, B. E.; Deb, S. P.; Deb, S.; Radhakrishnan, S. K.; Harada, H.; Grossman, S. R.

10.1101/2024.02.22.581532 — cancer biology — Posted on 2024-02-25

788 Deciphering the impact of cancer cells secretome and its derived-peptide VGF on breast cancer brain metastasis

Carvalho, R.; Santos, L.; Conde, I.; Leitao, R.; Ferreira, H. R. S.; Gomes, C.; Silva, A. P.; Schmitt, F.; Carvalho-Maia, C.; Lobo, J.; Jeronimo, C.; Paredes, J.; Ribeiro, A. S.

10.1101/2024.02.22.581537 — cancer biology — Posted on 2024-02-25

789 Effect of leaflet asymmetry on the stretching elasticity of lipid bilayers with phosphatidic acid

Drabik, D.; Hinc, P.; Stephan, M.; Cavalcanti, R. R. M.; Czogalla, A.; Dimova, R.

10.1101/2022.10.12.511874 — biophysics — Posted on 2024-02-25

790 Contractile to extensile transitions and mechanical adaptability enabled by activity in cytoskeletal structures

Lamtyugina, A.; Banerjee, D. S.; Qiu, Y.; Vaikuntanathan, S.

10.1101/2024.02.22.581411 — biophysics — Posted on 2024-02-25

791 MaskGraphene: Advancing joint embedding, clustering, and batch correction for spatial transcriptomics using graph-based self-supervised learning

Hu, Y.; Li, Y.; Xie, M.; Rao, M.; Liu, Y. H.; Zhou, X. M.

10.1101/2024.02.21.581387 — bioinformatics — Posted on 2024-02-25

792 Deep phenotypic profiling of neuroactive drugs in larval zebrafish

Gendelev, L.; Taylor, J.; Myers-Turnbull, D.; Chen, S.; McCarroll, M. N.; Arkin, M. R.; Kokel, D.; Keiser, M. J.

10.1101/2024.02.22.581657 — bioinformatics — Posted on 2024-02-25

793 Empowering high-throughput high-content analysis of 3D tumor models: Open-source software for automated non-confocal image analysis

Wiggin, N.; Cook, C. J.; Black, M.; Cadena, I. A.; Rahal-Arabi, S.; Fogg, K. C.

10.1101/2024.02.20.581231 — bioengineering — Posted on 2024-02-25

794 The genetic landscape, gene flow and adaptation in Ladakh highlanders of trans-Himalayas

Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.

10.1101/2024.02.05.579041 — genetics — Posted on 2024-02-25

795 Non-cell-autonomous regulation of germline proteostasis by insulin/IGF-1 signaling via the intestinal peptide transporter PEPT-1

Muhammad, T.; Edwards, S. L.; Morphis, A. C.; Johnson, M. V.; Oliveira, V. D.; Chamera, T.; Liu, S.; Nguyen, N. G. T.; Li, J.

10.1101/2024.02.22.581543 — developmental biology — Posted on 2024-02-25

796 Drivers of Vessel Progenitor Fate Define Intermediate Mesoderm Dimensions by Inhibiting Kidney Progenitor Specification

Perens, E. A.; Yelon, D.

10.1101/2024.02.22.581649 — developmental biology — Posted on 2024-02-25

797 5-Aza-Cytidine Enhances Terminal Polyadenylation Site Usage for Full-Length Transcripts in Cells

Ogunsola, S.; Liu, L.; Das, U.; Xie, J.

10.1101/2024.02.22.581641 — cell biology — Posted on 2024-02-25

798 Ilamycins are dual inhibitors of ClpX and ClpC1 involved in proteostasis in Mycobacteria

Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.

10.1101/2024.02.24.581832 — microbiology — Posted on 2024-02-25

799 Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs

Midha, A.; Oser, L.; Schlosser-Brandenburg, J.; Laubcshat, A.; Mugo, R. M.; Musimbi, Z. D.; Höfler, P.; Kundik, A.; Hayani, R.; Adjah, J.; Groenhagen, S.; Tieke, M. H.; Elizalde-Velazquez, L. E.; Kühl, A. A.; Klopfleisch, R.; Tedin, K.; Rausch, S.; Hartmann, S.

10.1101/2024.02.21.581410 — immunology — Posted on 2024-02-25

800 Differential cell type-specific function of the aryl hydrocarbon receptor and its repressor in diet-induced obesity and fibrosis

Graelmann, F. J.; Gondorf, F.; Majlesain, Y.; Niemann, B.; Klepac, K.; Gottschalk, M.; Mayer, M.; Iriady, I.; Hatzfeld, P.; Lindenberg, S. K.; Wunderling, K.; Thiele, C.; Abdullah, Z.; He, W.; Hiller, K.; Haendler, K.; Beyer, M. D.; Ulas, T.; Pfeifer, A.; Esser, C.; Weighardt, H.; Förster, I.; Reverte-Salisa, L.

10.1101/2024.02.22.581524 — immunology — Posted on 2024-02-25

801 Development And Characterization Of A Non-Human Primate Model Of Disseminated Synucleinopathy

Rico, A. J.; Corcho, A.; Chocarro, J.; Ariznabarreta, G.; Roda, E.; Honrubia, A.; Arnaiz Esteban, P.; Lanciego, J. L.

10.1101/2023.12.15.571818 — neuroscience — Posted on 2024-02-25

802 Cross-species modeling and enhancement of cognitive control with striatal brain stimulation

Reimer, A. E.; Dastin-van Rijn, E. M.; Kim, J.; Mensinger, M. E.; Sachse, E. M.; Wald, A.; Hoskins, E.; Singh, K.; Alpers, A.; Cooper, D.; Lo, M.-C.; de Oliveira, A. R.; Simandl, G.; Stephenson, N.; Widge, A. S.

10.1101/2024.02.16.580680 — neuroscience — Posted on 2024-02-25

803 Diagnostic of head blight and leaf blotch diseases of wheat in Sweden using a mycobiome isolation approach

Kaur, H.; Vilvert, E.; Corrales Gutierrez, M. A.; Zhan, J.; Douchkov, D.; Desiderio, F.; Velez, H.; Bourras, S.

10.1101/2024.01.09.574850 — plant biology — Posted on 2024-02-25

804 Hyperbaric Oxygen-Induced acute lung injury: A Mouse Model Study on Pathogenesis and Recovery Dynamics

Wang, S.; Li, Z.; Xu, G.; Bao, X.

10.1101/2024.02.23.581279 — physiology — Posted on 2024-02-25

805 Ovarian disrupting effects and mechanisms of long- and short-chain per- and polyfluoroalkyl substances in mice

Pattarawat, P.; Zhan, T.; Fan, Y.; Zhang, J.; Yang, H.; Zhang, Y.; Moyd, S.; Douglas, N. C.; Urbanek, M.; Buckley, B.; Burdette, J.; Zhang, Q.; Kim, J.-Y. J.; Xiao, S.

10.1101/2024.02.20.581034 — pharmacology and toxicology — Posted on 2024-02-25

806 Predicting Antibody and ACE2 Affinity for SARS-CoV-2 BA.2.86 and JN.1 with In Silico Protein Modeling and Docking

Yasa, S. R.; Guirales-Medrano, S.; Jacob Machado, D.; Ford, C. T.; Janies, D.

10.1101/2023.11.22.568364 — bioinformatics — Posted on 2024-02-25

807 Cellpose3: one-click image restoration for improved cellular segmentation

Stringer, C.; Pachitariu, M.

10.1101/2024.02.10.579780 — bioinformatics — Posted on 2024-02-25

808 Discovery of novel compounds and target mechanisms using a high throughput, multiparametric phenotypic screen in a human neuronal model of Tuberous Sclerosis

Williams, L. A.; Ryan, S. J.; Joshi, V.; Lewarch, C.; Elder, A.; McManus, O.; Godard, P.; Sridhar, S.; Jacques, J.; Grooms, J.; Fink, J. J.; Zhang, H.; Gillard, M.; Pegurier, C.; Sabnis, Y.; Andre, V.; Steward, L.; Dedeurwaerdere, S.; Devinsky, O.; Wolff, C.; Dempsey, G. T.

10.1101/2024.02.22.581652 — neuroscience — Posted on 2024-02-25

809 Interpretable deep learning framework for understanding molecular changes in human brains with Alzheimer's disease: implication for microglia activation and sex differences

Trivedi, M. R.; Joshi, A. M.; Shay, J.; Readhead, B. P.; Wilson, M. A.; Su, Y.; Reiman, E. M.; Wu, T.; Wang, Q.

10.1101/2023.12.18.572226 — neuroscience — Posted on 2024-02-25

810 Emergence of preference coding in the macaque lateral prefrontal cortex by neurofeedback of unit activity related to working memory

Noritake, A.; Samejima, K.; Watanabe, M.; Sakagami, M.

10.1101/2023.11.29.568968 — neuroscience — Posted on 2024-02-25

811 Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival

Kang, J.; Huang, G.; Ma, L.; Tong, Y.; Shahapal, A.; Chen, P.; Shen, J.

10.1101/2023.10.06.561293 — neuroscience — Posted on 2024-02-25

812 Cortical tracking of speech is reduced in adults who stutter when listening for speaking

Gastaldon, S.; Busan, P.; Molinaro, N.; Lizarazu, M.

10.1101/2024.02.23.581767 — neuroscience — Posted on 2024-02-25

813 An uncommon phosphorylation mode regulates the activity and protein-interactions of N-acetylglucosamine kinase

Celik, A.; Beyer, I.; Fiedler, D.

10.1101/2024.02.23.581760 — biochemistry — Posted on 2024-02-24

814 Mesencephalic projections to the nucleus accumbens shell modulate value updating during probabilistic reversal learning

Zühlsdorff, K.; Piller, S.; Sala-Bayo, J.; Zhukovsky, P.; Lamla, T.; Nissen, W.; von Heimendahl, M.; Deiana, S.; Nicholson, J. R.; Robbins, T.; Alsiö, J.; Dalley, J. W.

10.1101/2024.02.24.581852 — animal behavior and cognition — Posted on 2024-02-25

815 Five-leaf generalizations of the D-statistic revealthe directionality of admixture

Leppälä, K.; da Silva Coelho, F. A.; Richter, M.; Albert, V. A.; Lindqvist, C.

10.1101/2024.02.24.581856 — genetics — Posted on 2024-02-25

816 Building predictive Markov State Models of ion channel permeation from Molecular Dynamics

Catacuzzeno, L.; Leonardi, M. V.; Franciolini, F.; Domene, C.; Michelucci, A.; Furini, S.

10.1101/2024.02.22.581422 — biophysics — Posted on 2024-02-24

817 Rhodoquinone-dependent electron transport chain is essential for C. elegans survival in hydrogen sulfide environments

Romanelli-Cedrez, L.; Vairoletti, F.; Salinas, G.

10.1101/2024.02.23.581771 — biochemistry — Posted on 2024-02-24

818 Degradation of IKAROS prevents epigenetic progression of T cell exhaustion in a novel antigen-specific assay

Tay, T.; Bommakanti, G.; Jaensch, E.; Gorthi, A.; Reddy, I.; Hu, Y.; Zhang, R.; Doshi, A.; Tan, S. L.; Brucklacher-Waldert, V.; Prickett, L.; Kurasawa, J.; Overstreet, M.; Criscione, S.; Buenrostro, J.; Mele, D.

10.1101/2024.02.22.581548 — genomics — Posted on 2024-02-24

819 Living in a multi-stressor world: nitrate pollution and thermal stress interact to affect amphibian larvae

Sinai, N.; Eterovick, P. C.; Kruger, N.; Oetken, B.; Ruthsatz, K.

10.1101/2024.02.22.581589 — ecology — Posted on 2024-02-24

820 Impact of Spruce Plantation on Plant Diversity

Manuzi, V.; Balestra, S.; Gatti, P.; Losapio, G.

10.1101/2024.02.22.581586 — ecology — Posted on 2024-02-24

821 BET Degraders Reveal BRD4 Disruption of 7SK and P-TEFb is Critical for Effective Reactivation of Latent HIV in CD4+ T-cells

Turner, A.-M. W.; Bashore, F. M.; Falcinelli, S. D.; Fox, J. A.; Keller, A. L.; Fenton, A. D.; Geyer, R. F.; Allard, B.; Kirchherr, J. L.; Archin, N. M.; James, L. I.; Margolis, D. M.

10.1101/2024.02.23.581756 — molecular biology — Posted on 2024-02-24

822 Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin

Woods, K. E.; Akhter, S.; Rodriguez, B. L.; Townsend, K. A.; Smith, N. C.; Wambua, A. N.; Craddock, V.; Santa, E. E.; Manson, D. E.; Abisado-Duque, R. G.; Oakley, B. R.; Hancock, L. E.; Miao, Y.; Blackwell, H. E.; Chandler, J. R.

10.1101/2024.02.24.581676 — microbiology — Posted on 2024-02-24

823 Mechanism of phage sensing and abortion by toxin-antitoxin-chaperone systems

Mets, T.; Kurata, T.; Ernits, K.; Johansson, M. J. O.; Craig, S. Z.; Evora, G. M.; Buttress, J. A.; Odai, R.; Coppieters't Wallant, K.; Nakamoto, J. A.; Shyrokova, L.; Egorov, A. A.; Doering, C. R.; Brodiazhenko, T.; Laub, M. T.; Tenson, T.; Strahl, H.; Martens, C.; Harms, A.; Garcia-Pino, A.; Atkinson, G. C.; Hauryliuk, V.

10.1101/2024.02.24.581848 — microbiology — Posted on 2024-02-24

824 Exploring the repository of de novo designed bifunctional antimicrobial peptides through deep learning

Dong, R.; Liu, R.; Liu, Z.; Liu, Y.; Zhao, G.; Li, H.; Hou, S.; Ma, X.; Kang, H.; Liu, J.; Guo, F.; Zhao, P.; Wang, J.; Wang, C.; Wu, X.; Ye, S.; Zhu, C.

10.1101/2024.02.23.581845 — microbiology — Posted on 2024-02-24

825 BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils.

Leal, V. N. C.; Bork, F.; von Guilleaume, J. C.; Greve, C. L.; Bugl, S.; Danker, B.; Bittner, Z. A.; Grimbacher, B.; Pontillo, A.; Weber, A. N.

10.1101/2024.02.23.581733 — immunology — Posted on 2024-02-24

826 Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes

Tojima, R.; Nagata, K.; Ito, N.; Arai, T.; Ishii, K.; Ito, T.; Kasakura, K.; Nishiyama, C.

10.1101/2024.02.24.581851 — immunology — Posted on 2024-02-24

827 Loss of the scavenger receptor MARCO results in uncontrolled vomocytosis of fungi from macrophages.

Onyishi, C. U.; Fejer, G.; Mukhopadhyay, S.; Gordon, S.; May, R. C.

10.1101/2024.02.22.581301 — immunology — Posted on 2024-02-24

828 Antibiotic Bacteria Interaction: Dataset and Benchmarking.

Chatterjee, S.; Majumdar, A.; Chouzenoux, E.

10.1101/2024.02.22.581405 — bioengineering — Posted on 2024-02-24

829 Is myeloid-derived growth factor a ligand of the sphingosine-1-phosphate receptor 2?

Zheng, Y.-S.; Liu, Y.-L.; Xu, Z.-G.; He, C.; Guo, Z.-Y.

10.1101/2024.02.23.581834 — biochemistry — Posted on 2024-02-24

830 Structural Determinants for Activity of the Antidepressant Vortioxetine at Human and Rodent 5-HT3 receptors

Lopez-Sanchez, U.; Munro, L. J.; Ladefoged, L. K.; Pedersen, A. J.; Brun, C. C.; Lyngby, S. M.; Baud, D.; Pedersen, M. G.; Lummis, S. C. R.; Bang-Andersen, B.; Schiott, B.; Chipot, C.; Schoehn, G.; Neyton, J.; Dehez, F.; Nury, H.; Kristensen, A. S.

10.1101/2024.02.23.581731 — biochemistry — Posted on 2024-02-24

831 Direction-aware functional class scoring enrichment analysis of Infinium DNA methylation data

Ziemann, M.; Abeysooriya, M.; Bora, A.; Lamon, S.; Kasu, M. S.; Norris, M. W.; Wong, Y. T.; Craig, J. M.

10.1101/2024.02.22.581670 — genomics — Posted on 2024-02-24

832 Genetic evolution analysis of hemagglutinin and neuraminidase genes of H9N2 avian influenza virus in external environment of some areas of Yunnan Province, China from 2020 to 2023

Liu, Z.; Chen, Y.; Fu, X.-Q.; Sun, Y.; Zhang, M.-L.; Han, X.; Zhao, X.; Zhou, J.

10.1101/2024.02.24.581849 — molecular biology — Posted on 2024-02-24

833 Synthetic type III-E CRISPR-Cas effectors for programmable RNA-targeting

Brogan, D. J.; Dalla Benetta, E.; Wang, T.; Lin, C. P.; Chen, F.; Li, H.; Lin, C.; Komives, E. A.; Akbari, O. S.

10.1101/2024.02.23.581838 — molecular biology — Posted on 2024-02-24

834 m6A landscape is more pervasive when Trypanosoma brucei exits the cell cycle

Serra, L.; Silva Pereira, S.; Viegas, I.; Machado, H.; Lopez-Escobar, L.; Figueiredo, L. M.

10.1101/2024.02.23.581781 — molecular biology — Posted on 2024-02-24

835 Anti-viral defense by an ADP-ribosyltransferase that targets mRNA to block translation

Vassallo, C. N.; Doering, C. R.; Laub, M. T.

10.1101/2024.02.24.581662 — microbiology — Posted on 2024-02-24

836 A mitochondrial SET domain protein is essential in Trypanosoma brucei and required for mitochondrial morphology and function

Knight, E. W.; Aquino Ventura, R.; Mukala, N.; Morris, M. T.

10.1101/2024.02.23.581798 — microbiology — Posted on 2024-02-24

837 Toxoplasma type II effector GRA15 has limited influence in vivo

Merritt, E. F.; Kochanowsky, J. A.; Herve, P.; Watson, A. A.; Koshy, A. A.

10.1101/2024.02.23.581829 — microbiology — Posted on 2024-02-24

838 Androgens modulate the immune profile in a mouse model of polycystic ovary syndrome

Torstensson, S.; Ascani, A.; Risal, S.; Lu, H.; Zhao, A.; Espinosa, A.; Lindgren, E.; Johansson, M. H.; Eriksson, G.; Barakat, M.; Karlsson, M. C. I.; Svensson, C.; Benrick, A.; Stener-Victorin, E.

10.1101/2024.02.22.581579 — immunology — Posted on 2024-02-24

839 Unconventional IFNω-like genes dominate the type I IFN locus and the constitutive antiviral responses in bats

Geng, R.; Wang, Q.; Yao, Y.-L.; Shen, X.-R.; Jia, J.-K.; Wang, X.; Zhu, Y.; Li, Q.; Shi, Z.-L.; Zhou, P.

10.1101/2024.02.22.581518 — immunology — Posted on 2024-02-24

840 Hypoxia disrupts circadian rhythms in astrocytes and causes synapse engulfment defects

Li, L.; Pasca, A. M.; Choi, J.; Shin, C. H.; Htun, S.; Mestan, S.; Voss, A.; Shadrach, J. L.; Puno, A.; Nagar, D.; Ramirez, N.; Rojo, D.; Lee, S. H.; Gibson, E. M.; Kaltschmidt, J. A.; Sloan, S. A.; Chung, W.-S.

10.1101/2024.02.22.581651 — neuroscience — Posted on 2024-02-24

841 Proteomics-based characterization of ribosome heterogeneity in adult mouse organs

BELIN, S.; Schaeffer, J.; Brunchault, M.-R.; Hesse, A.-M.; Decourt, C.; Combes, F.; NAWABI, H.; Coute, Y.

10.1101/2024.02.23.581691 — biochemistry — Posted on 2024-02-24

842 Placental cytotrophoblast microvillar stabilization is required for cell-cell fusion

Duan, W. K.; Shaha, S. Z.; Patel, K. J.; Domingo, I. K.; Riddell, M.

10.1101/2024.02.22.581647 — developmental biology — Posted on 2024-02-24

843 Comparative metagenomic study unveils bacterial communities and their putative involvement in ecological success of two pine-feeding Ips beetle holobionts

Roy, A.; Khara, A.; Chakraborty, A.; Modlinger, R.

10.1101/2024.02.23.581803 — microbiology — Posted on 2024-02-24

844 Molecular, Cellular, and Developmental Organization of the Mouse Vomeronasal Organ at Single Cell Resolution

Hills, M. H.; Ma, L.; Fang, A.; Chiremba, T.; Malloy, S.; Scott, A. R.; Perera, A. G.; Yu, R.

10.1101/2024.02.22.581574 — neuroscience — Posted on 2024-02-24

845 Code Multiplexed Nanocapacitor Arrays for Scalable Neural Recordings

Weaver, S.; Chen, Y.; Renz, A. F.; Choi, W.; Vyza, Y.; Schlotter, T.; Vulic, K.; Kim, D.; Atzeni, G.; Momotenko, D.; Nakatsuka, N.; Jang, T.; Vörös, J.

10.1101/2024.02.22.581578 — neuroscience — Posted on 2024-02-24

846 Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools

Fujise, K.; Rosenfeld, M.; Rafiq, N. M.

10.1101/2024.02.22.581435 — neuroscience — Posted on 2024-02-24

847 Deep Learning Behavioral Phenotyping System in the Diagnosis of Parkinson's Disease with Drosophila melanogaster

Dong, K.; Burch, A.; Huang, K.

10.1101/2024.02.23.581846 — neuroscience — Posted on 2024-02-24

848 Miniature linear and split-belt treadmills reveal mechanisms of adaptive motor control in walking Drosophila

Pratt, B.; Lee, S.-Y.; Chou, G.; Tuthill, J. C.

10.1101/2024.02.23.581656 — neuroscience — Posted on 2024-02-24

849 Graphene microelectrode arrays, 4D structured illumination microscopy, and a machine learning-based spike sorting algorithm permit the analysis of ultrastructural neuronal changes during neuronal signalling in a model of Niemann-Pick disease type C

Lu, M.; Hui, E.; Brockhoff, M.; Trauble, J.; Fernandez-Villegas, A.; Burton, O. J.; Lamb, J.; Ward, E.; Hooper, P. J.; Tadbier, W.; Laubli, N. F.; Hofmann, S.; Kaminski, C. F.; Lombardo, A.; Kaminski Schierle, G. S.

10.1101/2024.02.22.581570 — neuroscience — Posted on 2024-02-24

850 C. elegans display antipathy behavior towards food after contemporaneous integration of nutritional needs and dietary lipid availability

Stuhr, N.; Ramos, C.; Turner, C.; Soukas, A. A.; Curran, S. P.

10.1101/2024.02.23.581740 — physiology — Posted on 2024-02-24

851 O6-Alkylguanine-DNA Alkyltransferase Maintains Genomic Integrity During Peroxynitrite-Mediated DNA Damage by Forming DNA-Protein Crosslinks

Chakraborty, S.; Mukherjee, G.; Chakrabarty, A.; Chowdhury, G.

10.1101/2024.02.22.581550 — pharmacology and toxicology — Posted on 2024-02-24

852 Contractility of cardiac and skeletal muscle tissue increases with environmental stiffness

Kah, D.; Lell, J.; Wach, T.; Spoerrer, M.; Dessalles, C. A.; Kraxner, J.; Wiedenmann, S.; Gerum, R. C.; Vergarajauregui, S.; Esser, T. U.; Boehringer, D.; Engel, F. B.; Thievessen, I.; Fabry, B.

10.1101/2024.02.23.581737 — biophysics — Posted on 2024-02-24

853 Advancing Drug-Target Interactions Prediction: Leveraging a Large-Scale Dataset with a Rapid and Robust Chemogenomic Algorithm.

Guichaoua, G.; Pinel, P.; Hoffmann, B.; Azencott, C.-A.; Stoven, V.

10.1101/2024.02.22.581599 — bioinformatics — Posted on 2024-02-24

854 Positioning of negative feedback loops within immune signaling pathways influences host fitness through noise in AMP expression

Asgari, D.; Tate, A. T.

10.1101/2024.02.22.581613 — evolutionary biology — Posted on 2024-02-24

855 Laboratory application of the Aquascope approach of automated imaging and classification for long-term plankton monitoring

Merkli, S.; Reyes, M.; Pomati, F.

10.1101/2024.02.23.581739 — ecology — Posted on 2024-02-24

856 Large herbivores link plant phenology and abundance in arctic tundra

Post, E.; Higgins, R. C.; Boving, P. S.; John, C.; Post, M.; Kerby, J.

10.1101/2024.02.23.581818 — ecology — Posted on 2024-02-24

857 Environmental drivers of the decline of the fen orchid, Liparis loeselii

Andersen, D. K.; Ejrnaes, R.; Minter, M.; Riis, T.; Vinther, E.; Bruun, H. H.

10.1101/2024.02.22.581533 — ecology — Posted on 2024-02-24

858 Gene Expression Reactomes Across Species Do Not Correlate with Gene Structural Similarity

Chen, W.; Chai, Y.; Cui, N. Y.; Gopinath, A.; Zhang, D.

10.1101/2024.02.23.581748 — molecular biology — Posted on 2024-02-24

859 A Machine Learning Framework to Identify the Correlates of Disease Severity in Acute Arbovirus Infection

Herder, V.; Caporale, M.; MacLean, O.; Pintus, D.; Huang, X.; Nomikou, K.; Palmalux, N.; Nichols, J.; Scivoli, R.; Boutell, C.; Taggart, A.; Allan, J.; Malik, H.; Ilia, G.; Gu, Q.; Ronchi, G. F.; Furnon, W.; Zientara, S.; Breard, E.; Antonucci, D.; Capista, S.; Giansante, D.; Cocco, A.; Mercante, M. T.; Di Ventura, M.; Filipe, A. D. S.; Puggioni, G.; Sevilla, N.; Stewart, M.; Ligios, C.; Palmarini, M.

10.1101/2024.02.23.581333 — microbiology — Posted on 2024-02-24

860 Arg18 substitutions reveal the capacity of the HIV-1 capsid protein for non-fullerene assembly

Schirra, R. T.; dos Santos, N. F.; Ganser-Pornillos, B. K.; Pornillos, O.

10.1101/2024.02.23.580350 — microbiology — Posted on 2024-02-24

861 Expectations about presence enhance the influence of content-specific expectations on low-level orientation judgements

Haarsma, J.; Kaltenmaier, A.; Fleming, S.; Kok, P.

10.1101/2024.02.22.581334 — neuroscience — Posted on 2024-02-24

862 Design and construction towards a pan-microbial toolkit

Gilbert, C.; Crits-Christoph, A.; Ledieu-Dherbecourt, E.; Kang, S. C.; Brumwell, S. L.; Lee, H. H.; Ostrov, N.

10.1101/2024.02.23.581749 — synthetic biology — Posted on 2024-02-24

863 CACTI: An in-silico drug-target prediction tool through the integration of chemogenomic data and clustering analysis

Godinez Macias, K. P.; Winzeler, E. A.

10.1101/2024.02.23.581805 — bioinformatics — Posted on 2024-02-24

864 Nova-ST: Nano-Patterned Ultra-Dense platform for spatial transcriptomics

Poovathingal, S.; Davie, K.; Vandepoel, R.; Poulvellarie, N.; Verfaillie, A.; Corthout, N.; Aerts, S.

10.1101/2024.02.22.581576 — genomics — Posted on 2024-02-24

865 Escape from X inactivation is directly modulated by levels of Xist non-coding RNA

Hauth, A.; Panten, J.; Kneuss, E.; Picard, C.; Servant, N.; Rall, I.; Perez-Rico, Y. A.; Clerquin, L.; Servaas, N.; Villacorta, L.; Jung, F.; Luong, C.; Chang, H. Y.; Stegle, O.; Odom, D. T.; Loda, A.; heard, E.

10.1101/2024.02.22.581559 — developmental biology — Posted on 2024-02-24

866 Scywalker: scalable end-to-end data analysis workflow for nanopore single-cell transcriptome sequencing

De Rijk, P.; Watzeels, T.; Kucukali, F.; Van Dongen, J.; Faura, J.; Willems, P.; De Deyn, L.; Duchateau, L.; Grones, C.; Eekhout, T.; De Pooter, T.; Joris, G.; Rombauts, S.; De Rybel, B.; Rademakers, R.; Van Breusegem, F.; Strazisar, M.; Sleegers, K.; De Coster, W.

10.1101/2024.02.22.581508 — bioinformatics — Posted on 2024-02-24

867 Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network

Dibyachintan, S.; Dube, A. K.; Bradley, D.; Lemieux, P.; Dionne, U.; Landry, C.

10.1101/2024.02.23.581840 — evolutionary biology — Posted on 2024-02-24

868 Admixture with cultivated sunflower likely facilitated establishment and spread of wild sunflower (H. annuus) in Argentina

Hernandez, F.; Vercellino, R. B.; Todesco, M.; Bercovich, N.; Alvarez, D.; Brunet, J.; Presotto, A.; Rieseberg, L. H.

10.1101/2024.02.22.581669 — evolutionary biology — Posted on 2024-02-24

869 stMMR: accurate and robust spatial domain identification from spatially resolved transcriptomics with multi-modal feature representation

Zhang, D.; Yu, N.; Li, W.; Sun, X.; Zou, Q.; Li, X.; Yuan, Z.; Zhang, W.; Gao, R.

10.1101/2024.02.22.581503 — bioinformatics — Posted on 2024-02-24

870 A VHL-1/HIF-1/SQRD1/COL-88 axis links extracellular matrix formation with longevity in Caenorhabditis elegans

10.1101/2024.02.22.581513 — genetics — Posted on 2024-02-24

871 Foveal RGCs develop altered calcium dynamics weeks after photoreceptor ablation

Xu, Z.; Kunala, K.; Murphy, P.; Puthussery, T.; McGregor, J. E.; Patak, L.

10.1101/2023.05.30.542908 — physiology — Posted on 2024-02-24

872 Emerin deficiency drives MCF7 cells to an invasive phenotype

Hansen, E.; Wang, M.; Rolling, C.; Holaska, J. M.

10.1101/2024.02.21.581379 — cancer biology — Posted on 2024-02-24

873 Decoupling of the Onset of Anharmonicity between a Protein and Its Surface Water around 200 K

Zheng, L.; Huang, J.; Tyagi, M.; Sakai, V. G.; Yamada, T.; O'Neill, H.; Zhang, Q.; Zhou, B.

10.1101/2023.10.18.562890 — biophysics — Posted on 2024-02-24

874 A procedure for solid phase extractions using metal oxide coated silica column in lipidomics

Takeda, H.; Takeuchi, M.; Hasegawa, M.; Miyamoto, J.; Tsugawa, H.

10.1101/2023.10.15.562428 — bioengineering — Posted on 2024-02-24

875 The number and pattern of viral genomic reassortments are not necessarily identifiable from segment trees

Lin, Q.; Goldberg, E. E.; Leitner, T.; Molina-Paris, C.; King, A. A.; Romero-Severson, E.

10.1101/2023.09.20.558687 — evolutionary biology — Posted on 2024-02-24

876 Antibiotic treatment does not abrogate protection against Mycobacterium tuberculosis reinfection

Ganchua, S. K.; Maiello, P.; Chao, M.; Hopkins, F.; Mugahid, D.; Lin, P. L.; Fortune, S. M.; Flynn, J. L.

10.1101/2023.12.19.570845 — microbiology — Posted on 2024-02-24

877 Development of a major histocompatibility complex class II conditional knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves.

Ubogu, E.; Conner, J.; Wang, Y.; Yadav, D.; Saunders, T.

10.1101/2023.07.24.550421 — immunology — Posted on 2024-02-24

878 Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia

Bonifazi, A.; Ellenberger, M.; Farino, Z. J.; Aslanoglou, D.; Rais, R.; Pereira, S.; Mantilla-Rivas, J. O.; Boateng, C. A.; Eshleman, A. J.; Janowsky, A.; Hahn, M. K.; Schwartz, G. J.; Slusher, B. S.; Newman, A. H.; Freyberg, Z.

10.1101/2024.02.21.581451 — neuroscience — Posted on 2024-02-24

879 Local field potential sharp waves with diversified impact on cortical neuronal encoding of haptic input

Kristensen, S. S.; Jorntell, H.

10.1101/2023.11.10.566542 — neuroscience — Posted on 2024-02-24

880 Can higher aggressiveness effectively compensate for a virulence deficiency in plant pathogen? A case study of Puccinia triticina's fitness evolution in a diversified varietal landscape

Fontyn, C.; Meyer, K. J.; Boixel, A.-L.; Picard, C.; Destanque, A.; Marcel, T. C.; Suffert, F.; Goyeau, H.

10.1101/2023.06.09.544363 — plant biology — Posted on 2024-02-24

881 Kinetochores grip microtubules with directionally asymmetric strength

Larson, J. D.; Heitkamp, N. A.; Murray, L. E.; Popchock, A. R.; Biggins, S.; Asbury, C. L.

10.1101/2024.02.22.581622 — biophysics — Posted on 2024-02-24

882 Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice

Novais, E. J.; Ottone, O. K.; Brown, E. V.; Madhu, V.; Tran, V. A.; Dighe, A. S.; Solga, M. D.; Manchel, A.; Lepore, A. C.; Risbud, M. K.

10.1101/2024.02.23.581794 — cell biology — Posted on 2024-02-24

883 PLK1-Mediated Phosphorylation Cascade Activates the Mis18 Complex to Ensure Centromere Inheritance

Parashara, P.; Medina-Pritchard, B.; Abad, M. A.; Sotelo-Parrilla, P.; Thamkachy, R.; Grundei, D.; Zou, J.; Das, V.; Yan, Z.; Kelly, D. A.; McHugh, T.; Rappsilber, J.; Jeyaprakash, A. A.

10.1101/2024.02.23.581399 — cell biology — Posted on 2024-02-24

884 Topographical changes in extracellular matrix during skin fibrosis and recovery can be evaluated using automated image analysis algorithms

Wyetzner, R. H.; Segal, E.; Jussila, A. R.; Atit, R. P.

10.1101/2024.02.23.581810 — cell biology — Posted on 2024-02-24

885 p24-Tango1 interactions ensure ER-Golgi interface stability and efficient transport

Yang, K.; Feng, Z.; Pastor-Pareja, J. C.

10.1101/2024.02.23.580604 — cell biology — Posted on 2024-02-24

886 An age-specific platelet differentiation path from hematopoietic stem cells contributes to exacerbated thrombosis

Poscablo, D.; Worthington, A.; Smith-Berdan, S.; Manso, B.; Adili, R.; Cool, T.; Reggiardo, R.; Dahmen, S.; Beaudin, A.; Boyer, S. W.; Holinstat, M.; Forsberg, C.

10.1101/2024.02.23.581812 — cell biology — Posted on 2024-02-24

887 A series of spontaneously blinking dyes for super-resolution microscopy

Holland, K. L.; Plutkis, S. E.; Daugird, T. A.; Sau, A.; Grimm, J. B.; English, B. P.; Zheng, Q.; Dave, S.; Rahman, F.; Xie, L.; Dong, P.; Tkachuk, A. N.; Brown, T. A.; Singer, R. H.; Liu, Z. J.; Galbraith, C. G.; Musser, S. M.; Legant, W. R.; Lavis, L. D.

10.1101/2024.02.23.581625 — cell biology — Posted on 2024-02-24

888 Epigenetic Control of Adaptive or Homeostatic Splicing of Alternative Exons and Prolactin Gene Expression During Interval-Training Activities of Pituitary Cells

Liu, L.; Nguyen, H.; Das, U.; Ogunsola, S.; Yu, J.; Lei, L.; Kung, M.; Pejhan, S.; Rastegar, M.; Xie, J.

10.1101/2024.02.23.581772 — cell biology — Posted on 2024-02-24

889 PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCFFBXL4

Nguyen-Dien, G. T.; Townsend, B.; Kulkarni, P.; Kozul, K.-L.; Ooi, S. S.; Eldershaw, D.; Weeratunga, S.; Liu, M.; Jones, M. J.; Millard, S. S.; Ng, D. C.; Pagano, M.; Komander, D.; Lazarou, M.; Collins, B. M.; Pagan, J. K.

10.1101/2024.02.23.581814 — cell biology — Posted on 2024-02-24

890 Predicting the direction of phenotypic difference

Gokhman, D.; Harris, K. D.; Carmi, S.; Greenbaum, G.

10.1101/2024.02.22.581566 — genetics — Posted on 2024-02-23

891 The ciliary protein C2cd3 is required for mandibular musculoskeletal tissue patterning

Brooks, E. C.; Han, S. J. Y.; Bonatto Paese, C. L.; Lewis, A. A.; Aarnio-Peterson, M.; Brugmann, S. A.

10.1101/2024.02.23.581730 — developmental biology — Posted on 2024-02-23

892 Activity-dependent regulation of vascular cholesterol metabolism acts as a negative feedback mechanism for neurovascular coupling

Profaci, C. P.; Foreman, K. L.; Spieth, L.; Coelho-Santos, V.; Berghoff, S. A.; Fontaine, J. T.; Jeffrey, D. A.; Palecek, S. P.; Shusta, E. V.; Saher, G.; Shih, A. Y.; Dabertrand, F.; Daneman, R.

10.1101/2024.02.23.581685 — neuroscience — Posted on 2024-02-23

893 Knockout of AMPA receptor binding protein Neuron-Specific Gene 2 (NSG2) enhances associative learning and cognitive flexibility

Zimmerman, A. J.; Serrano-Rodriguez, A.; Wilson, S.; Linsenbardt, D.; Brigman, J.; Weick, J. P.

10.1101/2024.02.23.581648 — neuroscience — Posted on 2024-02-23

894 Emergence of a synergistic scaffold in the brains of human infants

Varley, T. F.; Sporns, O.; Stevenson, N. J.; Welch, M. G.; Myers, M. M.; Vanhatalo, S.; Tokariev, A.

10.1101/2024.02.23.581375 — neuroscience — Posted on 2024-02-23

895 ErbB inhibition rescues nigral dopamine neuron hyperactivity and repetitive behaviors in a mouse model of fragile X syndrome

D'Addario, S. L.; Rosina, E.; Massaro Cenere, M.; Bagni, C.; Mercuri, N. B.; Ledonne, A.

10.1101/2024.02.23.581801 — neuroscience — Posted on 2024-02-23

896 Vitamin B12 variants structure soil microbial communities despite soil's vast reservoir of B12.

Hallberg, Z. F.; Nicolas, A. M.; Alvarez-Aponte, Z. I.; Mok, K. C.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J.; Carlson, H. K.; Firestone, M. K.; Taga, M. E.

10.1101/2024.02.12.580003 — microbiology — Posted on 2024-02-23

897 Chromosome-level genome assembly and annotation of the social amoeba Dictyostelium firmibasis

Edelbroek, B.; Kjellin, J.; Jerlstrom-Hultqvist, J.; Koskiniemi, S.; Soderbom, F.

10.1101/2024.02.22.581529 — genomics — Posted on 2024-02-23

898 A transcription network underlies the dual genomic coordination of mitochondrial biogenesis

Xu, H.

10.1101/2024.01.25.577217 — genetics — Posted on 2024-02-23

899 The Origin and Evolution of Sex Peptide and Sex Peptide Receptor Interactions

Peng, J.; Svetec, N.; Molina, H.; Zhao, L.

10.1101/2023.11.19.567744 — evolutionary biology — Posted on 2024-02-23

900 Macrophages undergo functionally significant reprogramming of nucleotide metabolism upon classical activation

John, S. V.; Seim, G. L.; Erazo-Flores, B. J.; Steill, J.; Freeman, J.; Votava, J. A.; Arp, N. L.; Qing, X.; Stewart, R.; Knoll, L. J.; Fan, J.

10.1101/2023.12.27.573447 — cell biology — Posted on 2024-02-23

901 Targeted Viromes and Total Metagenomes Capture Distinct Components of Bee Gut Phage Communities

Sbardellati, D. L.; Vannette, R. L.

10.1101/2024.02.12.579852 — microbiology — Posted on 2024-02-23

902 Rational protein engineering to enhance MHC-independent T cell receptors

Chang, J.; Landmann, J. H.; Chang, T.-C.; Tenzin, Y.; Warrington, J. M.; Selli, M. E.; Ritchey, J.; Hsu, Y.-S.; Slade, M.; Gupta, D. K.; DiPersio, J. F.; Singh, N.

10.1101/2024.02.22.581571 — immunology — Posted on 2024-02-23

903 Interpretable deep learning framework towards understanding molecular changes in human brains with Alzheimer's disease: implication for microglia activation and sex differences

Trivedi, M. R.; Joshi, A. M.; Shay, J.; Readhead, B. P.; Wilson, M. A.; Su, Y.; Reiman, E. M.; Wu, T.; Wang, Q.

10.1101/2023.12.18.572226 — neuroscience — Posted on 2024-02-23

904 Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease

Zhuang, X.; Lemak, J.; Sridhar, S.; Nelson, A. B.

10.1101/2024.02.19.581062 — neuroscience — Posted on 2024-02-23

905 Laboratory evolution reveals transcriptional mechanisms underlying thermal adaptation of Escherichia coli

Rychel, K.; Chen, K.; Catoiu, E. A.; Olson, C. A.; Sandberg, T. E.; Gao, Y.; Xu, S.; Hefner, Y.; Szubin, R.; Patel, A.; Feist, A. M.; Palsson, B.

10.1101/2024.02.22.581624 — systems biology — Posted on 2024-02-23

906 Neutrophil extracellular traps drive acute lupus flares with skin and kidney inflammation triggered by ultraviolet irradiation

Lyu, X.; Li, M.; Zhang, P. L.; Wei, W.; Werth, V. P.; Liu, M.-L.

10.1101/2023.12.23.572573 — pathology — Posted on 2024-02-23

907 The αC-β4 loop controls the allosteric cooperativity between nucleotide and substrate in the catalytic subunit of protein kinase A

Olivieri, C.; Wang, Y.; Walker, C.; Subrahmanian, M. V.; Ha, K. N.; Bernlohr, D. A.; Gao, J.; Camilloni, C.; Vendruscolo, M.; Taylor, S. S.; Veglia, G.

10.1101/2023.09.12.557419 — biophysics — Posted on 2024-02-23

908 High-resolution single-particle imaging at 100-200 keV with the Gatan Alpine direct electron detector.

Chan, L. M.; Courteau, B. J.; Maker, A.; Wu, M.; Basanta, B.; Mehmood, H.; Bulkley, D.; Joyce, D.; Lee, B. C.; Mick, S.; Gulati, S.; Lander, G. C.; Verba, K. A.

10.1101/2024.02.14.580363 — biophysics — Posted on 2024-02-23

909 Fitting linear mixed model in genetic association studies: an efficient and exact method

Guan, Y.; Levy, D.

10.1101/2023.10.25.563975 — bioinformatics — Posted on 2024-02-23

910 Short-chain fatty acids propionate and butyrate control growth and differentiation linked to cellular metabolism

Nshanian, M.; Geller, B. S.; Gruber, J. J.; Chleilat, F.; Lancaster, S.; Camarillo, J. M.; Kelleher, N. L.; Zhao, Y.; Snyder, M. P.

10.1101/2024.01.11.575111 — genetics — Posted on 2024-02-23

911 Nuclear instance segmentation and tracking for preimplantation mouse embryos

Nunley, H.; Shao, B.; Denberg, D.; Grover, P.; Singh, J.; Avdeeva, M.; Joyce, B.; Kim-Yip, R.; Kohrman, A.; Biswas, A.; Watters, A.; Gal, Z.; Kickuth, A.; Chalifoux, M.; Shvartsman, S.; Brown, L.; Posfai, E.

10.1101/2023.03.14.532646 — developmental biology — Posted on 2024-02-23

912 Park7 deletion leads to age- and sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes

Helgueta, S.; Heurtaux, T.; Sciortino, A.; Gui, Y.; Ohnmacht, J.; Mencke, P.; Boussaad, I.; Halder, R.; Garcia, P.; Krueger, R.; Mittelbronn, M.; Buttini, M.; Sauter, T.; Sinkkonen, L.

10.1101/2024.02.23.581743 — molecular biology — Posted on 2024-02-23

913 A synergistic culture dependent and independent approach reveals a conserved wheat seed mycobiome

Becker, L. E.; Marshall, D.; Cubeta, M. A.

10.1101/2024.02.22.581674 — microbiology — Posted on 2024-02-23

914 Stability of the Wheat Seed Mycobiome Across North Carolina's Longitudinal Gradient

Becker, L.; Hawkes, C. V.; Heiniger, R. W.; Cubeta, M. A.

10.1101/2024.02.22.581680 — microbiology — Posted on 2024-02-23

915 The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection

Lambert, C.; Bachmann, C.; Gaillard, M.; Hautcoeur, A.; Wongdontree, P.; Gloux, K.; Guilbert, T.; Mechats, C.; Prost, B.; Solgadi, A.; Abreu, S.; Andrieu, M.; Poyart, C.; Gruss, A.; FOUET, A.

10.1101/2023.06.07.543851 — microbiology — Posted on 2024-02-23

916 Interleukin-1 receptor antagonist is a conserved driver of tuberculosis

Kotov, D. I.; Lee, O. V.; Ji, D. X.; Jaye, D. L.; Suliman, S.; Gabay, C.; Vance, R. E.

10.1101/2023.10.27.564420 — immunology — Posted on 2024-02-23

917 Kaempferol exerts anti-inflammatory effects by accelerating Treg development via AhR-mediated and PU.1/IRF4-dependent transactivation of the Aldh1a2/RALDH2 gene in dendritic cells

Takahashi, M.; Nagata, K.; Watanuki, Y.; Yamaguchi, M.; Minamikawa, N.; Katagiri, M.; Zhao, W.; Ito, N.; Yashiro, T.; Nishiyama, C.

10.1101/2024.02.21.581328 — immunology — Posted on 2024-02-23

918 Investigating the effects of repetitive paired-pulse transcranial magnetic stimulation on visuomotor training using TMS-EEG.

Sasaki, R.; Hand, B. J.; Liao, W.-Y.; Semmler, J. G.; Opie, G. M.

10.1101/2024.02.21.581468 — neuroscience — Posted on 2024-02-23

919 Spiral ganglion neuron degeneration in deafened rats involves innate and adaptive immune responses not requiring complement

Gansemer, B. M.; Rahman, M. T.; Zhang, Z.; Green, S. H.

10.1101/2024.02.21.581500 — neuroscience — Posted on 2024-02-23

920 Stability from subspace rotations and traveling waves

Batabyal, T.; Brincat, S. L.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M. K.; Miller, E. K.

10.1101/2024.02.19.581020 — neuroscience — Posted on 2024-02-23

921 Enhancement of brain atlases with laminar coordinate systems: Flatmaps and barrel column annotations

Bolanos-Puchet, S.; Teska, A.; Hernando, J. B.; Lu, H.; Romani, A.; Schürmann, F.; Reimann, M. W.

10.1101/2023.08.24.554204 — neuroscience — Posted on 2024-02-23

922 Distinctive Whole-brain Cell-Types Predict Tissue Damage Patterns in Thirteen Neurodegenerative Conditions

Pak, V.; Adewale, Q.; Bzdok, D.; Dadar, M.; Zeighami, Y.; Iturria Medina, Y.

10.1101/2023.06.08.544227 — neuroscience — Posted on 2024-02-23

923 A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency

Kuhn, B. N.; Cannella, N.; Crow, A.; Lunerti, V.; Gupta, A.; Walterhouse, S.; Allen, C.; Chalhoub, R.; Dereschewitz, E.; Roberts, A.; Cockerham, M.; Beeson, A.; Nall, R.; Palmer, A. A.; Hardiman, G.; Solberg-Woods, L.; Chung, D.; Ciccocioppo, R.; Kalivas, P.

10.1101/2024.02.22.581440 — neuroscience — Posted on 2024-02-23

924 Diffusion MRS tracks distinct trajectories of neuronal development in the cerebellum and thalamus of rat neonates.

Ligneul, C.; Qiu, L.; Clarke, W. T.; Jbabdi, S.; Palombo, M.; Lerch, J.

10.1101/2023.10.16.562599 — neuroscience — Posted on 2024-02-23

925 Conserved neural dynamics and computations across species in olfaction

Ling, D.; Hanson Moss, E.; Smith, C. L.; Deng, F.; Kroeger, R.; Reimer, J. L.; Raman, B.; Arenkiel, B. R.

10.1101/2023.04.24.538157 — neuroscience — Posted on 2024-02-23

926 Optimising the production of dsRNA biocontrols in microbial systems using multiple transcriptional terminators.

Ross, S. J.; Owen, G.; Hough, J.; Philips, A.; Maddelein, W.; Ray, J.; Kilby, P.; Dickman, M. J.

10.1101/2024.02.22.581520 — synthetic biology — Posted on 2024-02-23

927 Mammalian Cell Models of the Distal Convoluted Tubule: A Systematic Review of Cell Lines, Culture Condition and Gene Expression

Zhong, C.; Sun, Z.; Grillo, A.; Walsh, S. B.; Siew, K.

10.1101/2024.02.23.581724 — physiology — Posted on 2024-02-23

928 Elucidating TolC Protein Dynamics: Structural Shifts Facilitate Efflux Mediated β-lactam Resistance

Kantarcioglu, I.; Gaszek, I. K.; Guclu, T. F.; Yildiz, M. S.; Atilgan, A. R.; Toprak, E.; ATILGAN, C.

10.1101/2024.02.22.581573 — biophysics — Posted on 2024-02-23

929 Identification and characterization of a bacterial periplasmic solute binding protein that binds L-amino acid amides.

Smith, O. B.; Frkic, R. L.; Rahman, M. G.; Jackson, C. J. J.; Kaczmarski, J. A.

10.1101/2024.02.22.581678 — biochemistry — Posted on 2024-02-23

930 Modern Insights into Muscle Glycogen Phosphorylase Activity

Kiriaev, L.; Oakhill, J. S.; Tiong, C. F.; Seto, J. T.; Crossman, V. G.; Quinlan, K. G. R.; North, K. N.; Houweling, P. J.; Ling, N. X. Y.

10.1101/2024.02.22.581477 — biochemistry — Posted on 2024-02-23

931 Elevated levels of iodide promote peroxidase-mediated protein iodination and inhibit protein chlorination

Jokumsen, K. V.; Huhle, V. H.; Hagglund, P. M.; Davies, M. J.; Gamon, L. F.

10.1101/2024.02.23.581700 — biochemistry — Posted on 2024-02-23

932 Wild communities of Morpho butterflies reveal Spiroplasma endosymbiont with inflated genome size and peculiar evolution

Jonathan, F.; Lopez-Villavicencio, M.; Vincent, D.; Rachel, F.; Camilo, S.; Karina, L. S.-B.; Patrick, B.; Andre, V. L. F.; Carolina, P.-D.; Violaine, L.

10.1101/2024.02.22.581604 — evolutionary biology — Posted on 2024-02-23

933 Improved Serodiagnosis of Trypanosoma vivax Infections in Cattle Reveals Higher Infection Rates in the Livestock Regions of Argentina

Bontempi, I. A.; Arias, D. G.; Castro, G. V.; Peverengo, L. M.; Diaz, G. F.; Allassia, M.; Greif, G.; Marcipar, I.

10.1101/2024.02.22.581515 — ecology — Posted on 2024-02-23

934 Automated plankton monitoring suggests a key role of microzooplankton and temperature for predicting dynamics of phytoplankton size classes

Merkli, S.; Merz, E.; Reyes, M.; Ntetsika, P.; Dennis, S.; Isles, P. D. F.; Kyathanahally, S.; Baity-Jesi, M.; To, S.-W.; Merico, A.; Pomati, F.

10.1101/2024.02.23.581723 — ecology — Posted on 2024-02-23

935 Habitat isolation diminishes potential of self-organised pattern formation to promote local diversity in metacommunities

Philipp, L.; Klauschies, T.; Guill, C.

10.1101/2024.02.22.581536 — ecology — Posted on 2024-02-23

936 Experimental validation of ecological coexistence theory to forecast extinction under rising temperatures.

Terry, C.

10.1101/2024.02.22.581553 — ecology — Posted on 2024-02-23

937 Comparative pollinator conservation potential of coffee agroforestry relative to coffee monoculture and tropical rainforest in the DR Congo

Depecker, J.; Vandelook, F.; Jordaens, K.; Dorchin, A.; Ntumba, B.; Broeckhoven, I.; Dhed'a, B.; Devriese, A.; Deckers, L.; Stoffelen, P.; Honnay, O.

10.1101/2024.02.23.581744 — ecology — Posted on 2024-02-23

938 Activity of DNA polymerase κ across the genome in human fibroblasts

Torres, M. C.; Sun, D.; Spratt, T. E.

10.1101/2024.02.22.581598 — cell biology — Posted on 2024-02-23

939 TFIIB-termination factor interaction affects termination of transcription on a genomewide scale

O'Brien, M. J.; Schrader, J. M.; Ansari, A.

10.1101/2024.02.22.581640 — molecular biology — Posted on 2024-02-23

940 Cre-Lox miRNA-delivery technology optimized for inducible microRNA and gene-silencing studies in zebrafish.

Guo, F.; Malik, A.; Wang, H.; Hall, T. E.; Giacomotto, J.

10.1101/2024.02.22.581357 — molecular biology — Posted on 2024-02-23

941 Dating ammonia-oxidizing bacteria with abundant eukaryotic fossils

Liao, T.; Wang, S.; Zhang, H.; Eva, S.; Luo, H.

10.1101/2024.02.23.581699 — molecular biology — Posted on 2024-02-23

942 Interferons and tuft cell numbers are bottlenecks for persistent murine norovirus infection

Aggarwal, S.; Walker, F. C.; Weagley, J. S.; McCune, B. T.; Wu, X.; Schreifer, L.; Makimaa, H.; Lawrence, D.; Sridhar, P.; Baldridge, M. T.

10.1101/2024.02.22.581634 — microbiology — Posted on 2024-02-23

943 Power-to-Vitamins: Producing Folate (Vitamin B9) from Renewable Electric Power and CO2 with a Microbial Protein System

Schmitz, L. M.; Kreitli, N.; Obermaier, L.; Weber, N.; Rychlik, M.; Angenent, L. T.

10.1101/2024.02.22.581687 — microbiology — Posted on 2024-02-23

944 The impact of Bacillus coagulans X3 on available nitrogen content, bacterial community composition, and nitrogen functional gene levels when composting cattle manure

Liu, B.; Chen, W.; Wang, Z.; Guo, Z.; Li, Y.; Xu, L.; Wu, M.; Yin, H.

10.1101/2024.02.23.581714 — microbiology — Posted on 2024-02-23

945 Food Fermentation in Space Is Possible, Distinctive, and Beneficial

Coblentz, M.; Evans, J. D.; Kothe, C. I.; Mak, T.; Rodriguez Valeron, N.; Chwalek, P.; Wejendorp, K.; Garg, S.; Pless, L.; Mak, S.; Sorensen, P. M.; Jahn, L. J.; Ekblaw, A.

10.1101/2024.02.23.579929 — microbiology — Posted on 2024-02-23

946 Distinct impacts of each anti-anti-sigma factor ortholog of the chlamydial Rsb partner switching mechanism on development in Chlamydia trachomatis

Junker, S.; Singh, V.; Al-Saadi, A. G. M.; Wood, N. A.; Hamilton-Brehm, S. D.; Ouellette, S. P.; Fisher, D. J.

10.1101/2024.02.22.581593 — microbiology — Posted on 2024-02-23

947 Design, optimization, and inference of multiphasic decay of infectious virus particles

Seurat, J.; Gerbino, K.; Meyer, J. R.; Borin, J.; Weitz, J.

10.1101/2024.02.23.581735 — microbiology — Posted on 2024-02-23

948 Memory load influences our preparedness to act on visual representations in working memory without affecting their accessibility

Nasrawi, R.; Mautner-Rohde, M.; van Ede, F.

10.1101/2024.02.23.581707 — neuroscience — Posted on 2024-02-23

949 Investigating the ability of music to induce calm in young adults.

Shepherd, D.; Pedersen, M.; Vashista, G.; Kercher, A.; Hautus, M. J.

10.1101/2024.02.22.581668 — neuroscience — Posted on 2024-02-23

950 HippoMaps: Multiscale cartography of the human hippocampal formation

DeKraker, J.; Cabalo, D. G.; Royer, J.; Khan, A. R.; Karat, B.; Benkarim, O.; Rodriguez-Cruces, R.; Frauscher, B.; Pana, R.; Hansen, J. Y.; Misic, B.; Valk, S. L.; Kirschner, M.; Bernasconi, A.; Bernasconi, N.; Muenzing, S.; Axer, M.; Amunts, K.; Evans, A. C.; Bernhardt, B. C.

10.1101/2024.02.23.581734 — neuroscience — Posted on 2024-02-23

951 ProT-Diff: A Modularized and Efficient Approach to De Novo Generation of Antimicrobial Peptide Sequences through Integration of Protein Language Model and Diffusion Model

Wang, X.-F.; Tang, J.-Y.; Liang, H.; Sun, J.; Dorje, S.; Peng, B.; Ji, X.-W.; Li, Z.; Zhang, X.-E.; Wang, D.-B.

10.1101/2024.02.22.581480 — synthetic biology — Posted on 2024-02-23

952 CanLncG4: A database curated for the assessment of G4s in the lncRNAs dysregulated in various human cancers

Sharma, S.; Yusuf, M.; Barbhuiya, N. H.; Ramolia, H.; Shukla, C.; Singh, D.; Datta, B.

10.1101/2024.02.21.581359 — bioinformatics — Posted on 2024-02-23

953 CNVeil enables accurate and robust tumor subclone identification and copy number estimation from single-cell DNA sequencing data

Yuan, W.; Luo, C.; Hu, Y.; Zhang, L.; Wen, Z.; Liu, Y. H.; Mallory, X.; Zhou, X. M.

10.1101/2024.02.21.581409 — bioinformatics — Posted on 2024-02-23

954 Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics

Li, G.; Li, H.; Ndou, P. A.; Franco, M.; Qiang, Y.; Li, X.; Buffet, P. A.; Dao, M.; Karniadakis, G. E.

10.1101/2024.02.22.581664 — bioengineering — Posted on 2024-02-23

955 Electron-Activated Dissociation and Collision-Induced Dissociation Glycopeptide Fragmentation for Improved Glycoproteomics

Macauslane, K. L.; Pegg, C. L.; Nouwens, A. S.; Kerr, E. D.; Seitanidou, J.; Schulz, B. L.

10.1101/2024.02.22.581095 — biochemistry — Posted on 2024-02-23

956 How Fungi Biosynthesize 3-Nitropropanoic Acid: the Simplest yet Lethal Mycotoxin

Johnson, C. W.; Ohashi, M.; Tang, Y.

10.1101/2024.02.22.581660 — biochemistry — Posted on 2024-02-23

957 Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression

Parmar, S.; Bume, D. D.; Connelly, C. M.; Boer, R. E.; Prestwood, P. R.; Wang, Z.; Labuhn, H.; Sinnadurai, K.; Feri, A.; Ouellet, J.; Homan, P.; Numata, T.; Schneekloth, J. S.

10.1101/2024.02.23.581746 — biochemistry — Posted on 2024-02-23

958 A specific phosphorylation-dependent conformational switch of SARS-CoV-2 nucleoprotein inhibits RNA binding

Botova, M.; Camacho-Zarco, A. R.; Tognetti, J.; Bessa, L. M.; Guseva, S.; Mikkola, E.; Salvi, N.; Maurin, D.; Herrmann, T.; Blackledge, M.

10.1101/2024.02.22.579423 — biochemistry — Posted on 2024-02-23

959 The maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehavioral impairment in mice

Coley, E.; Lum, G.; Pronovost, G.; Ozcan, E.; Yu, K.; Mcdermott, J.; chakhoyan, A.; Goldman, E.; Vuong, H.; Paramo, J.; Chu, A.; Calkins, K.; Hsiao, E. Y.

10.1101/2024.02.22.581439 — animal behavior and cognition — Posted on 2024-02-23

960 Trends in genome diversity of small populations under a conservation program: a case study of two French chicken breeds

Bortoluzzi, C.; Restoux, G.; Rouger, R.; Desnoues, B.; Petitjean, F.; Bosse, M.; Tixier-Boichard, M.

10.1101/2024.02.22.581528 — genomics — Posted on 2024-02-23

961 A comprehensive personal omics clinical interpreter based on genomic and transcriptomic profiles

Liu, Y.; Chen, Q.; Chen, Q.; Sang, L.; Wang, Y.; Shi, L.; Zheng, Y.; Guo, L.; Yu, Y.

10.1101/2024.02.22.581482 — genomics — Posted on 2024-02-23

962 An egg sabotaging mechanism drives non-Mendelian transmission in mice

Clark, F. E.; Greenberg, N. L.; Silva, D. M. Z. A.; Trimm, E.; Skinner, M.; Walton, R. Z.; Rosin, L. F.; Lampson, M. A.; Akera, T.

10.1101/2024.02.22.581453 — genetics — Posted on 2024-02-23

963 Thymidine Phosphorylase Mediates SARS-CoV-2 Spike Protein Enhanced Thrombosis in K18-hACE2TG Mice

Roytenberg, R.; Yue, H.; DeHart, A.; Kim, E.; Bai, F.; Kim, Y.; Denning, K.; Kwei, A.; Zhang, Q.; Liu, J.; Zheng, L.; Li, W.

10.1101/2024.02.23.581661 — cell biology — Posted on 2024-02-23

964 Antagonistic Roles of Tau and MAP6 in Regulating Neuronal Development

Sun, X.; Yu, W.; Baas, P. W.; Toyooka, K.; Qiang, L.

10.1101/2024.02.21.581458 — cell biology — Posted on 2024-02-23

965 Critical cis-parameters influence STructure Assisted RNA Translation (START) initiation on non-AUG codons in eukaryotes

TIDU, A.; ALGHOUL, F.; DESPONS, L.; ERIANI, G.; MARTIN, F.

10.1101/2024.02.23.581729 — molecular biology — Posted on 2024-02-23

966 Avian influenza virus circulation and immunity in a wild urban duck population prior to and during a highly pathogenic H5N1 outbreak

Wight, J.; Rahman, I.; Wallace, H. L.; Cunningham, J. T.; Roul, S.; Roberston, G. J.; Russell, R. S.; Xu, W.; Zhmendak, D.; Alkie, T. N.; Berhane, Y.; Hargan, K. E.; Lang, A. S.

10.1101/2024.02.22.581693 — microbiology — Posted on 2024-02-23

967 Capturing and Characterising Wild Yeast for Beer Brewing

Kerr, E. D.; Howes, M. T.; Schulz, B. L.

10.1101/2024.02.22.581081 — microbiology — Posted on 2024-02-23

968 CD81+ fibroblasts, a unique subpopulation with accelerated cellular senescence, exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis

Fu, L.; Yin, C.; Zhao, Q.; Guo, S.; Shao, W.; Xia, T.; Sun, Q.; Chen, L.; Wang, M.; Xia, H.

10.1101/2024.02.21.581332 — immunology — Posted on 2024-02-23

969 TKI-conditioned immunotherapy using uv-inactivated reovirus promotes survival in hepatocellular carcinoma, mediated by cytotoxic CD4+ T-cells

Hughes, R.; Moran, A.; Scott, K. J.; Appleton, E.; Bentham, M. J.; Ilett, E.; Melcher, A.; Macdonald, A.; Samson, A.; Griffin, S.

10.1101/2024.02.23.581738 — immunology — Posted on 2024-02-23

970 A site-wise reliability analysis of the ABCD diffusion fractional anisotropy data, impact of the scanner and analytical pipeline

Pan, Y.; Hong, L. E.; Acheson, A.; Thompson, P.; Jahanshad, N.; Yu, J.; Chen, C.; Ma, T.; Liu, H.-L.; Fieremans, E.; Kochunov, P.; Chen, S.

10.1101/2024.02.21.581460 — neuroscience — Posted on 2024-02-23

971 Spatial context non-uniformly modulates inter-laminar communication in the primary visual cortex

Xu, X.; Morton, M. P.; Hudson, N.; Nandy, A.; Jadi, M. P.

10.1101/2024.02.21.581417 — neuroscience — Posted on 2024-02-23

972 Salivary metabolomics in the family environment: A large-scale study investigating oral metabolomes in children and their parental caregivers

Rothman, J. A.; Piccerillo, H. L.; Riis, J. L.; Granger, D. A.; Thomas, E. A.; Whiteson, K. L.

10.1101/2024.02.21.581494 — systems biology — Posted on 2024-02-23

973 Olive Flowering dependence on winter temperatures - linking empirical results to a dynamic model

Smoly, I.; Elbaz, H.; Engelen, C.; Wechsler, T.; Elbaz, G.; Ben Ari, G.; Samach, A.; Friedlander, T.

10.1101/2024.02.21.581335 — plant biology — Posted on 2024-02-23

974 Adverse structural and mechanical remodelling of main pulmonary artery in experimental pulmonary arterial hypertension is associated with impaired right ventricle-pulmonary artery coupling and function

Mirani, B.; Dauz, J. D.; Yazaki, K.; Latifi, N.; Santerre, P.; Bendeck, M. P.; Simmons, C. A.; Friedberg, M. K.

10.1101/2024.02.20.581269 — physiology — Posted on 2024-02-23

975 Mechanical loading reveals an intrinsic cardiomyocyte stiffness contribution to diastolic dysfunction in murine cardiometabolic disease

Janssens, J. V.; Raaijmakers, A. J. A.; Koutsifeli, P.; Weeks, K. L.; Bell, J. R.; Van Eyk, J. E.; Curl, C. L.; Mellor, K. M.; Delbridge, L. M. D.

10.1101/2024.02.21.581448 — physiology — Posted on 2024-02-23

976 Identifying cancer cells from calling single-nucleotide variants in scRNA-seq data

Marot-Lassauzaie, V.; Beneyto-Calabuig, S.; Obermayer, B.; Velten, L.; Beule, D.; Haghverdi, L.

10.1101/2024.02.21.581377 — bioinformatics — Posted on 2024-02-23

977 Peptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy

Fischer, J. M.; Stewart, M.; Dai, M.; Drennan, S.; Holland, S.; Quentel, A.; Sabuncu, S.; Kingston, B. R.; Dengos, I.; Xiang, L.; Bonic, K.; Goncalves, F.; Yi, X.; Ranganathan, S.; Branchaud, B. P.; Muldoon, L. L.; Barajas, R. F.; Yildirim, A.

10.1101/2024.02.21.580762 — bioengineering — Posted on 2024-02-23

978 CYpHER: Catalytic extracellular targeted protein degradation with high potency and durable effect

Crook, Z. R.; Sevilla, G. P.; Young, P.; Girard, E. J.; Phi, T.-D.; Howard, M.; Olson, J. M.; Nairn, N. W.

10.1101/2024.02.21.581471 — bioengineering — Posted on 2024-02-23

979 Correlation between bioluminescent blinks and swimming behavior in the splitfin flashlight fish Anomalops katoptron

Jaegers, P.; Frischmuth, T.; Herlitze, S.

10.1101/2024.02.21.581075 — animal behavior and cognition — Posted on 2024-02-23

980 Genetic polymorphisms of Leukocyte Immunoglobulin-Like Receptor B3 (LILRB3) gene in African American kidney transplant recipients are associated with post-transplant graft failure

Sun, Z.; Yi, Z.; Wei, C.; Wang, W.; Cravedi, P.; Tedla, F.; Ward, S. C.; Azeloglu, E.; Schrider, D. R.; Li, Y.; Ali, S.; Ren, T.; Liu, S.; Liang, D.; Fu, J.; Liu, T.; Li, H.; Xi, C.; Vy, T. H.; Mosoyan, G.; Sun, Q.; Kumar, A.; Zhang, Z.; Farouk, S.; Campbell, K.; Ochando, J.; Lee, K.; Coca, S.; Xiang, J.; Connolly, P.; Gallon, L.; Colvin, R.; Menon, M.; Nadkarni, G.; He, J. C.; Kraft, M.; Jiang, X.; Zhang, X.; Zhang, W.; Chen, S.-h.; Heeger, P.; Zhang, W.

10.1101/2024.02.21.581383 — genetics — Posted on 2024-02-23

981 Changes in bird migration phenology over one century: a perspective from the Neotropical non-breeding grounds

Gutierrez-Carrillo, D. A.; Mateus-Aguilar, B.; Gomez, C.; Cadena, D.

10.1101/2024.02.21.581429 — ecology — Posted on 2024-02-23

982 The influence of environment on mosquito feeding patterns: a meta-analysis of "universal" DNA diet studies in a global context

O`Rorke, R.; Lee, M.; Clark, N. J.; Webster, T. M. U.; Wells, K.

10.1101/2024.02.21.581447 — ecology — Posted on 2024-02-23

983 Differential colonization and succession dynamics of marine bacteria on different plastic polymers

Davidov, K.; Itzahri, S.; Sinberger, L. A.; Oren, M.

10.1101/2024.02.21.581331 — ecology — Posted on 2024-02-23

984 DDR1 regulates RUNX1-CBFβ to control breast stem cell differentiation

Trepicchio, C.; Rauner, G.; Traugh, N.; Parrish, M.; Mal, Y.; Fein, D. E. C.; Kuperwasser, C.

10.1101/2024.02.21.581255 — developmental biology — Posted on 2024-02-23

985 Probabilistic Inference on Virtual Brain Models of Disorders

HASHEMI, M.; ZIAEE-MEHR, A.; WOODMAN, M.; PETKOSKI, S.; JIRSA, V.

10.1101/2024.02.21.581243 — neuroscience — Posted on 2024-02-23

986 Transient DREADD manipulation of the dorsal Dentate Gyrus in rats impairs disambiguation of similar place-outcome associations

Lim, J.; Souiki, A.; Ahmad, P.; Oomen, C. A.; Huis in 't Veld, G. J.; Lansink, C. S.; Pennartz, C.; Olcese, U.

10.1101/2024.02.20.581173 — neuroscience — Posted on 2024-02-23

987 Improved BOLD Detection with Sliced Inverse Regression

Lizarraga, A.; Li, K.

10.1101/2024.02.21.581434 — neuroscience — Posted on 2024-02-23

988 Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia

10.1101/2024.02.21.581451 — neuroscience — Posted on 2024-02-23

989 Ephrin-B2 promotes nociceptive plasticity and hyperalgesic priming through EphB2-MNK-eIF4E signaling in both mice and humans

David, E.; Yousuf, M. S.; Mei, H.-R.; Jain, A.; Krishnagiri, S.; Srikanth, K. D.; Dussor, G.; Dalva, M. B.; Price, T. J.

10.1101/2024.02.21.581414 — neuroscience — Posted on 2024-02-23

990 Contracted Functional Connectivity Profiles in Autism

Weber, C. F.; Kebets, V.; Benkarim, O.; Lariviere, S.; Wang, Y.; Ngo, A.; Jiang, H.; Chai, X. J.; Park, B.-y.; Milham, M.; Di Martino, A.; Valk, S. L.; Hong, S.-J.; Bernhardt, B.

10.1101/2024.02.21.581260 — neuroscience — Posted on 2024-02-23

991 Monkeys engage in visual simulation to solve complex problems

Ahuja, A.; Yusif Rodriguez, N.; Ashok, A. K.; Serre, T.; Desrochers, T.; Sheinberg, D.

10.1101/2024.02.21.581495 — neuroscience — Posted on 2024-02-23

992 The Dorsal Column Nuclei Scales Mechanical Allodynia During Neuropathic Pain

Upadhyay, A.; Gradwell, M. A.; Vajtay, T. J.; Conner, J.; Sayal, A. A.; Azadegan, C.; Patel, K. R.; Thackray, J. K.; Bohic, M.; Imai, F.; Ogundare, S. O.; Yoshida, Y.; Abdus-Saboor, I.; Azim, E.; Abraira, V. E. G.

10.1101/2024.02.20.581208 — neuroscience — Posted on 2024-02-23

993 Cholesterol modifies Nav1.7 - an in-silico and in-vitro analysis

Albani, S.; Eswaran, V. S. B.; Piergentili, A.; Souza, P. C. T. d.; Lampert, A.; Rossetti, G.

10.1101/2024.02.21.581348 — physiology — Posted on 2024-02-23

994 Systematic Identification of UBE2C As a Prognostic Biomarker and Correlated with Immunosuppression and Invasiveness in Glioma

Feng, H.; Fu, A.; Yang, R.; Qiao, F.

10.1101/2024.02.21.581365 — cancer biology — Posted on 2024-02-23

995 Metabolic shift to serine pathway induced by lipids confers oncogenic properties in non-transformed breast cells

Eduardo, M. B.; Cottone, G.; McCloskey, C. W.; Liu, S.; Zappia, M. P.; Benevolenskaya, E. V.; Islam, A. B. M. M. K.; Frolov, M. V.; Palma, F. R.; Gao, P.; Setya, J.; Gao, H.; Xuei, X.; Khokha, R.; Locasale, J.; Bonini, M. G.; Chandel, N. S.; Khan, S. A.; Clare, S. E.

10.1101/2024.02.21.581404 — cancer biology — Posted on 2024-02-23

996 Single-molecule Mapping of Amyloid-β Oligomer Insertion intoLipid Bilayers

DEY, A.; Patil, A.; Arumugam, S.; Maiti, S.

10.1101/2024.02.21.581487 — biophysics — Posted on 2024-02-23

997 Protein-structure-sensitive mid-infrared optoacoustic microscopy enables label-free assessment of drug therapy in myeloma cells

Gasparin, F.; Tietje, M. R.; Katab, E.; Nurdinova, A.; Yuan, T.; Chmyrov, A.; Uluc, N.; Jüstel, D.; Bassermann, F.; Ntziachristos, V.; Pleitez, M. A.

10.1101/2024.02.21.581391 — biophysics — Posted on 2024-02-23

998 Imaging and quantification of prostate cancer-associated bone by polarization-sensitive optical coherence tomography

Zhou, C.; JUNG, N.; XU, S.; GUERSETTI, F. E.; Lu, X.; WANG, Q.; LIANG, D.; MORRISSEY, C.; COREY, E.; TRUE, L.; Wang, R.; Tang, S.; Cox, M. E.

10.1101/2024.02.21.581336 — biophysics — Posted on 2024-02-23

999 Antidiabetic effect of 1-deazapurines derivatives with alpha-glucosidase Enzyme: A molecular tools approach

BOUKLI HACENE, F.; Cherrak, S. A.; Soufi, W.; Ghalem, S.

10.1101/2024.02.20.581286 — biophysics — Posted on 2024-02-23

1000 A highly scalable approach to topic modelling in single-cell data by approximate pseudobulk projection

Subedi, S.; Sumida, T. S.; Park, Y.

10.1101/2024.02.21.581497 — bioinformatics — Posted on 2024-02-23

1001 Systematically developing a registry of splice-site creating variants utilizing massive publicly available transcriptome sequence data

Iida, N.; Okada, A.; Kobayashi, Y.; Chiba, K.; Yatabe, Y.; Shiraishi, Y.

10.1101/2024.02.21.581470 — bioinformatics — Posted on 2024-02-23

1002 SpaCCC: Large language model-based cell-cell communication inference for spatially resolved transcriptomic data

Ji, B.-Y.; Xu, L.-W.; Peng, S.-L.

10.1101/2024.02.21.581369 — bioinformatics — Posted on 2024-02-23

1003 Large-scale characterization of cell niches in spatial atlases using bio-inspired graph learning

Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Bayraktar, O.; Theis, F. J.; Talavera-Lopez, C.; Lotfollahi, M.

10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-02-23

1004 PreMode predicts mode of action of missense variants by deep graph representation learning of protein sequence and structural context

Zhong, G.; Zhao, Y.; Zhuang, D.; Chung, W. K.; Shen, Y.

10.1101/2024.02.20.581321 — bioinformatics — Posted on 2024-02-23

1005 Development of a 3D in vitro human-sized model of cervical dysplasia to evaluate the delivery of ethyl cellulose-ethanol injection for the treatment of cervical dysplasia ablation

Cadena, I. A.; Adhikari, G.; Almer, A.; Jenne, M. A.; Obasi, N.; Zurita, N. F. S.; Rochefort, W. E.; Mueller, J. L.; Fogg, K. C.

10.1101/2024.02.20.581242 — bioengineering — Posted on 2024-02-23

1006 diaPASEF Enables High-throughput Proteomic Analysis of Host Cell Proteins for Biopharmaceutical Process Development

Tsukidate, T.; Stiving, A. Q.; Rivera, S.; Sahoo, A.; Madhabushi, S.; Li, X.

10.1101/2024.02.21.581388 — bioengineering — Posted on 2024-02-23

1007 Spherical Echo-Planar Time-resolved Imaging (sEPTI) for rapid 3D quantitative T2* and Susceptibility imaging

Wang, N.; Liao, C.; Cao, X.; Nishimura, M.; Brackenier, Y.; Yurt, M.; Gao, M.; Abraham, D.; Alkan, C.; Iyer, S. S.; Zhou, Z.; Kerr, A.; Haldar, J.; Setsompop, K.

10.1101/2024.02.21.581459 — bioengineering — Posted on 2024-02-23

1008 Revealing In Situ Molecular Profiles of Glomerular Cell Types and Substructures with Integrated Imaging Mass Spectrometry and Multiplexed Immunofluorescence Microscopy

Esselman, A. B.; Moser, F. A.; Tideman, L.; Migas, L. G.; Djambazova, K. V.; Colley, M. E.; Pingry, E. L.; Patterson, N. H.; Farrow, M. A.; Yang, H.; Fogo, A. B.; de Caestecker, M.; Van de Plas, R.; Spraggins, J. M.

10.1101/2024.02.21.581450 — biochemistry — Posted on 2024-02-23

1009 Assessment of Remediation Through Measuring Nuclear Respiratory Factor 1 (nrf1) Environmental Stressor Transcriptomic Gene Signatures

Morales, J. C.; Deoraj, A.; Felty, Q.; Lagos, L.; Yoo, C.; Roy, D.

10.1101/2024.02.21.581481 — genomics — Posted on 2024-02-23

1010 A chromosome-level genome assembly of Drosophila madeirensis, a fruit fly species endemic to the island of Madeira

Tomihara, K.; Llopart, A.; Yamamoto, D.

10.1101/2024.02.21.581469 — genomics — Posted on 2024-02-23

1011 A pan-tissue, pan-disease compendium of human orphan genes

Singh, U.; Haltom, J.; Guarnieri, J.; Li, J.; Seetharam, A.; Beheshti, A.; Aronow, B.; Wurtele, E. S.

10.1101/2024.02.21.581488 — evolutionary biology — Posted on 2024-02-23

1012 Quantifying vulnerability to plant invasion across global ecosystems

Pfadenhauer, W.; Bradley, B. A.

10.1101/2024.02.21.581382 — ecology — Posted on 2024-02-23

1013 Epigenetic regulation by TET1 in gene-environmental interactions influencing susceptibility to congenital malformations

van der Veer, B. K.; Chen, L.; Tsaniras, S. C.; Brangers, W.; Chen, Q.; Schroiff, M.; Custers, C.; Kwak, H. H. M.; Khoueiry, R.; Cabrera, R.; Gross, S. S.; Finnell, R. H.; Lei, Y.; Koh, K. P.

10.1101/2024.02.21.581196 — developmental biology — Posted on 2024-02-23

1014 Mucin MUC5B levels are reduced in the colonic epithelia of ulcerative colitis patients

Ding, W.; Koltun, W. A.; Yochum, G. S.

10.1101/2024.02.21.581373 — cell biology — Posted on 2024-02-23

1015 Mutational Analysis of an Antimalarial Drug Target PfATP4

Rachuri, S.; Nepal, B.; Shukla, A.; Ramanathan, A. A.; Morrisey, J. M.; Daly, T. M.; Mather, M. W.; Bergman, L. W.; Kortagere, S.; Vaidya, A. B.

10.1101/2024.02.21.581445 — microbiology — Posted on 2024-02-23

1016 Regulation of temporal cytokine production by co-stimulation receptors in TCR-T cells is lost in CAR-T cells

Patel, A.; Kutuzov, M. A.; Dustin, M.; van der Merwe, P. A.; Dushek, O.

10.1101/2024.02.21.581341 — immunology — Posted on 2024-02-23

1017 Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

D'Addabbo, A.; Tong, T.; Crooks, E.; Osawa, K.; Xu, J.; Thomas, A.; Allen, J.; Crispin, M.; Binley, J. M.

10.1101/2024.02.20.581329 — immunology — Posted on 2024-02-23

1018 Label free metabolic imaging to enhance the efficacy of Chimeric Antigen Receptor T cell therapy

Pham, D. L.; Cappabianca, D.; Forsberg, M.; Weaver, C.; Mueller, K. P.; Tommasi, A.; Vidugiriene, J.; Lauer, A.; Sylvester, K.; Bugel, M.; Capitini, C. M.; Saha, K.; Skala, M. C.

10.1101/2024.02.20.581240 — immunology — Posted on 2024-02-23

1019 Responses of neurons in macaque V4 to object and texture images

Lieber, J. D.; Oleskiw, T. D.; Simoncelli, E. P.; Movshon, J. A.

10.1101/2024.02.20.581273 — neuroscience — Posted on 2024-02-23

1020 Infant neural sensitivity to affective touch is associated with maternal postpartum depression

Nance, M. G.; Landsman, Z. T.; Gerling, G. J.; Puglia, M. H.

10.1101/2024.02.21.581204 — neuroscience — Posted on 2024-02-23

1021 Age-related dysregulation of the retinal transcriptome in African turquoise killifish

Bergmans, S.; Noel, N. C.; Masin, L.; Harding, E. G.; Krzywanska, A. M.; De Schutter, J. D.; Ayana, R.; Hu, C.-K.; Arckens, L.; Ruzycki, P. A.; Clark, B. S.; MacDonald, R. B.; Moons, L.

10.1101/2024.02.21.581372 — neuroscience — Posted on 2024-02-23

1022 ACE1 knockout in neurons selectively dysregulates the hippocampal renin angiotensin system and causes vascular loss

Jeon, S.; Salvo, M. A.; Alia, A. O.; Popovic, J.; Zagardo, M.; Chandra, S.; Nassan, M.; Gate, D.; Vassar, R.; Cuddy, L.

10.1101/2024.02.21.581402 — neuroscience — Posted on 2024-02-23

1023 Gustatory-neuron-supplied R-spondin-2 is required for taste bud replenishment

Xu, J.; de Araujo, A.; Xi, R.; Lin, X.; Lu, C.; Zhou, M.; Hankenson, K. D.; Margolskee, R. F.; Matsumoto, I.; de Lartigue, G.; Choi, M.; Jiang, P.

10.1101/2024.02.21.581408 — neuroscience — Posted on 2024-02-23

1024 Graph analysis of the guilt network highlights associations with subclinical anxiety and self-blame

Zareba, M. R.; Bielski, K.; Costumero, V.; Visser, M.

10.1101/2024.02.21.581371 — neuroscience — Posted on 2024-02-23

1025 Feature selectivity of corticocortical feedback along the primate dorsal visual pathway

Korkian, Y.; Nakhla, N.; Pack, C. C.

10.1101/2024.02.21.581426 — neuroscience — Posted on 2024-02-23

1026 Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high fat diet-related insulin resistance, steatosis and adipose dysfunction

Jin, Y.; Jarmasz, J. S.; Sultana, S.; Cordero-Monroy, L.; Taylor, C. G.; Zahradka, P.; Kardami, E.; Cattini, P. A.

10.1101/2024.02.21.581281 — physiology — Posted on 2024-02-23

1027 Impact of Cervical Lymphatic Obstruction on Brain Pathophysiology in Cervical Lymphedema Animal Models

Cheon, H.; Woo, D.-C.; Cha, S.; Chae, Y. J.; Maeng, I.; Oh, S. J.; Jeon, J. Y.

10.1101/2024.02.21.581490 — physiology — Posted on 2024-02-23

1028 Targeted NAD+ Delivery for Intimal Hyperplasia and Re-endothelialization: A Novel Anti-restenotic Therapy Approach

Yin, L.; Tong, Y.; Islam, Z. H.; Zhang, K.; Xie, R.; Burger, J.; Hoyt, N.; Kent, E. W.; Marcum, W. A.; Johnston, C.; Kanchetty, R.; Tetz, Z.; Stanisic, S.; Huang, Y.; Guo, L.-W.; Gong, S.; Wang, B.

10.1101/2024.02.20.581249 — pathology — Posted on 2024-02-23

1029 p300 KAT regulates SOX10 stability and function in human melanoma

Waddell, A.; Grbic, N.; Leibowitz, K.; Wyant, W. A.; Choudhury, S.; Park, K.; Collard, M.; Cole, P. A.; Alani, R. M.

10.1101/2024.02.20.581224 — cancer biology — Posted on 2024-02-23

1030 The MYCN 5' UTR as a therapeutic target in neuroblastoma

Volegova, M. P.; Brown, L. E.; Banerjee, U.; Dries, R.; Sharma, B.; Kennedy, A.; Porco, J. A.; George, R. E.

10.1101/2024.02.20.581230 — cancer biology — Posted on 2024-02-23

1031 Radiation-induced non-neoplastic cells senescence promoting the proliferation and invasiveness of GBM through SASP/JAK2-STAT3 Pathway

Nie, P.; Chen, J.; Zhang, J.

10.1101/2024.02.21.581353 — cancer biology — Posted on 2024-02-23

1032 Fast and accurate short read alignment with hybrid hash-tree data structure

Makino, J.; Ebisuzaki, T.; Himeno, R.; Hayashizaki, Y.

10.1101/2024.02.20.581311 — bioinformatics — Posted on 2024-02-23

1033 MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative

Yang, Z.; Cieza, B.; Reyes-Dumeyer, D.; Lee, A.; Ma, Y.; Yilmaz, E.; Lantigua, R.; Miller, G.; Brown, L.; Honig, L.; Ciener, B.; Leskinin, S.; Sivakumar, S.; Vardarajan, B.; Dugger, B.; Jin, L.-W.; Murray, M.; Dickson, D.; Rissman, R.; Hiniker, A.; Pericak-Vance, M.; Vance, J.; Foroud, T.; Kizil, C.; Teich, A.; Mayeux, R.; Tosto, G.

10.1101/2024.02.20.581250 — genetics — Posted on 2024-02-23

1034 Estimating distance to tipping point from dryland ecosystem images

Pichon, B.; Donnet, S.; Gounand, I.; Kefi, S.

10.1101/2024.02.20.581244 — ecology — Posted on 2024-02-23

1035 Price structure of traded honey, pollen and wax linked to winter survival of a honey bee colony

Kohli, M.

10.1101/2024.02.20.581238 — ecology — Posted on 2024-02-23

1036 Bycatch mitigation of endangered marine life

Villafafila, M.; Carpio, A.; Rivas, M. L.

10.1101/2024.02.20.581169 — developmental biology — Posted on 2024-02-23

1037 An analysis of contractile and protrusive cell behaviours at the superficial surface of the zebrafish neural plate

Araya, C.; Farlie, F.; Moon, L.; Rookyard, C.; Allison, L.; Vizcay-Barrena, G.; Fleck, R.; Tada, M.; Clarke, J.

10.1101/2024.02.20.581322 — developmental biology — Posted on 2024-02-23

1038 Normative and individual, non-normative intrinsic networks and the transition to impaired cognition

Zhang, Q.; Hudgins, S.; Struck, A. F.; Ankeeta, A.; Javidi, S. S.; Sperling, M. R.; Hermann, B. P.; Tracy, J. I.

10.1101/2024.02.20.581233 — neuroscience — Posted on 2024-02-23

1039 Superoxide enters neurons via LRRC8A-containing volume-regulated anion channels

Harris, K.; Uruk, G.; Won, S. J.; Mai, N.; Baxter, P.; Everaerts, K.; Sah, R.; Swanson, R. A.

10.1101/2024.02.20.580732 — neuroscience — Posted on 2024-02-23

1040 Gene Regulatory Network topology governs resistance and treatment escape in glioma stem-like cells

Park, J. H.; Hothi, P.; Lopez Garcia de Lomana, A.; Pan, M.; Calder, R.; Turkarslan, S.; Wu, W.-J.; Lee, H.; Patel, A. P.; Cobbs, C.; Huang, S.; Baliga, N. S.

10.1101/2024.02.02.578510 — systems biology — Posted on 2024-02-23

1041 Multilevel proteomic profiling of colorectal adenocarcinoma cell differentiation to characterize an intestinal epithelial model

Fekete, E. E.; Wang, A.; Creskey, M.; Cummings, S. E.; Lavoie, J. R.; Ning, Z.; Li, J.; Figeys, D.; Chen, R.; ZHANG, X.

10.1101/2024.02.19.581096 — systems biology — Posted on 2024-02-23

1042 Enable, Empower, Succeed: Harnessing Open Science for Antimicrobial Resistance Containment

Founou, L. L.; Lawal, O. U.; Djiyou, A.; Odih, E. E.; Amoako, D. G.; Fadanka, S.; Aworh, M. K.; Lukhele, S.; Nikolic, D.; Matimba, A.; Founou, R. C.

10.1101/2024.02.20.580892 — scientific communication and education — Posted on 2024-02-23

1043 Single-cell and single-nucleus RNA-sequencing from paired normal-adenocarcinoma lung samples provides both common and discordant biological insights.

Renaut, S.; Armero, V. S.; Boudreau, D. K.; Gaudreault, N.; Desmeules, P.; Theriault, S.; Mathieu, P.; Joubert, P.; Bosse, Y.

10.1101/2024.02.20.581199 — cancer biology — Posted on 2024-02-23

1044 Integrating short-read and long-read single-cell RNA sequencing for comprehensive transcriptome profiling in mouse retina

Wang, M.; Li, Y.; Wang, J.; Oh, S. H.; Chen, R.

10.1101/2024.02.20.581234 — bioinformatics — Posted on 2024-02-23

1045 Computed Tomography of Polymeric Biomedical Implants from Bench to Bedside

Pawelec, K.; Schoborg, T.; Shapiro, E.

10.1101/2024.02.20.581229 — bioengineering — Posted on 2024-02-23

1046 Engineering a three-dimensional multilayer multicellular model of endometrial cancer for high throughput drug screening and novel treatment methods

Cadena, I. A.; Rowlands, C.; Buchanan, M. R.; Jenne, M. A.; Keefe, B.; Almer, A.; Obasi, N.; Harris, C. G.; Rochefort, W. E.; Givens, B. E.; Fogg, K. C.

10.1101/2024.02.20.581239 — bioengineering — Posted on 2024-02-23

1047 Deep mutational scanning of Pneumocystis jirovecii dihydrofolate reductase reveals allosteric mechanism of resistance to an antifolate

Rouleau, F. D.; Dube, A. K.; Gagnon-Arsenault, I.; Dibyachintan, S.; Pageau, A.; Despres, P. C.; Lagüe, P.; Landry, C. R.

10.1101/2023.09.27.559786 — biochemistry — Posted on 2024-02-23

1048 Negative Life Events and Epigenetic Ageing: a Study in the Netherlands Twin Register

Gonggrijp, B. M. A.; van de Weijer, S. G. A.; Bijleveld, C. C. J. H.; Boomsma, D. I.; van Dongen, J.

10.1101/2024.02.20.581138 — genetics — Posted on 2024-02-23

1049 Recovery of a learned behavior despite partial restoration of neuronal dynamics after chronic inactivation of inhibitory neurons

Torok, Z.; Luebbert, L.; Feldman, J.; Duffy, A.; Nevue, A.; Wongso, S.; Mello, C.; Fairhall, A.; Pachter, L.; Gonzalez, W. G.; Lois, C.

10.1101/2023.05.17.541057 — neuroscience — Posted on 2024-02-23

1050 Optic nerve injury impairs intrinsic mechanisms underlying electrical activity in a resilient retinal ganglion cell

Zapadka, T. E.; Tran, N. M.; Demb, J. B.

10.1101/2024.02.20.581201 — neuroscience — Posted on 2024-02-23

1051 Symplasmic phloem loading and sub-cellular transport in storage roots are key factors for carbon allocation in cassava

Rüscher, D.; Vasina, V. V.; Knoblauch, J.; Bellin, L.; Pommerrenig, B.; Alseekh, S.; Fernie, A. R.; Neuhaus, H. E.; Knoblauch, M.; Sonnewald, U.; Zierer, W.

10.1101/2024.02.21.581442 — plant biology — Posted on 2024-02-23

1052 Molecular mechanisms of seasonal brain shrinkage and regrowth inSorex araneus

Thomas, W. R.; Dechmann, D. K. N.; Nieland, J.; Elverfeldt, D.; Carlson, D.; Baldoni, C.; Holm-Jacobsen, J.; Muturi, M.; Corthals, A.; Davalos, L.

10.1101/2023.10.02.560485 — genetics — Posted on 2024-02-23

1053 Land-use impacts on plant functional diversity throughout Europe

Rosa, F.; van Bodegom, P.; Hellweg, S.; Pfister, S.; Biurrun, I.; Boch, S.; Chytry, M.; Custerevska, R.; Dalle Fratte, M.; Damasceno, G.; Garbolino, E.; Lenoir, J.; Ozinga, W. A.; Penuelas, J.; Sabatini, F. M.; Schrodt, F.; Uogintas, D.; Byun, C.; Dolezal, J.; Dziuba, T.; Herault, B.; Martin-Fores, I.; Niinemets, U.; Peyre, G.; Scherer, L.

10.1101/2024.02.21.580945 — ecology — Posted on 2024-02-23

1054 Synaptopodin is required for efficient intercellular spread by bacterial pathogens

Vickery, J. M.; Toperzer, J. D.; Raab, J. E.; Hamilton, D. J.; Harju, T. B.; Huynh, T. N.; Zhou, L.; Lenz, L. L.; Colgan, S. P.; Russo, B. C.

10.1101/2023.04.25.537990 — microbiology — Posted on 2024-02-23

1055 Microtubules and actin filaments direct nuclear movement during the polarisation of Marchantia spore cells

Dolan, L.; Attrill, S. T.

10.1101/2024.02.23.581750 — plant biology — Posted on 2024-02-23

1056 Uncovering the Interleukin-12 Pharmacokinetic Desensitization Mechanism and Its Consequences with Mathematical Modeling

DeBonis, J.; Veiseh, O.; Igoshin, O. A.

10.1101/2024.02.20.581191 — bioengineering — Posted on 2024-02-23

1057 3D in vitro modeling of the exocrine pancreatic unit using tomographic volumetric bioprinting

Sgarminato, V.; Madrid-Wolff, J.; Boniface, A.; Ciardelli, G.; Tonda-Turo, C.; Moser, C.

10.1101/2023.01.23.525142 — bioengineering — Posted on 2024-02-23

1058 Skeletal progenitor LRP1 deficiency causes severe and persistent skeletal defects with WNT/planar cell polarity dysregulation.

Alhashmi, M.; Gremida, A. M.; Maharana, S. K.; Antonaci, M.; Kerr, A.; Al-Maslamani, N. A.; Liu, K.; Meschis, M. M.; Sutherland, H.; Wilson, P.; Clegg, P.; Wheeler, G. N.; van 't Hof, R. J.; Bou-Gharios, G.; Yamamoto, K.

10.1101/2023.07.11.548556 — developmental biology — Posted on 2024-02-23

1059 Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules

Chakraborty, S.; Martinez-Sanchez, A.; Beck, F.; Toro-Nahuelpan, M.; Hwang, I.-Y.; Noh, K.-M.; Baumeister, W.; Mahamid, J.

10.1101/2022.07.28.501854 — cell biology — Posted on 2024-02-23

1060 The assembly and efflux processes revealed by in situ structures of the ABC-type tripartite pump MacAB-TolC

Huo, T.; Zheng, W.; Yu, Z.; Wu, Y.; Ren, Q.; Cao, J.-L.; wang, z.; Shi, X.

10.1101/2024.02.22.581608 — microbiology — Posted on 2024-02-23

1061 Dissociable roles of neural pattern reactivation and transformation during recognition of words read aloud and silently: An MVPA study of the production effect

Bailey, L. M.; Matheson, H. E.; Fawcett, J. M.; Bodner, G. E.; Newman, A. J.

10.1101/2024.02.20.581164 — neuroscience — Posted on 2024-02-23

1062 Rejuvenating silicon probes for acute electrophysiology

Shoup, A.; Porwal, N.; Fakharian, M. A.; Hage, P.; Orozco, S. P.; Shadmehr, R.

10.1101/2024.02.20.581222 — neuroscience — Posted on 2024-02-23

1063 Neural decoding of the speech envelope: Effects of intelligibility and spectral degradation

MacIntyre, A. D.; Carlyon, R. P.; Goehring, T.

10.1101/2024.02.20.581129 — neuroscience — Posted on 2024-02-23

1064 A doubly stochastic renewal framework for partitioning spiking variability

Aghamohammadi, C.; Chandrasekaran, C.; Engel, T. A.

10.1101/2024.02.21.581457 — neuroscience — Posted on 2024-02-23

1065 Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis in mice fed a high-fat diet.

JO, y.-h.; Hwang, J.; jo, W.; Chua, S.; Schwartz, G. J.

10.1101/2024.02.20.581228 — neuroscience — Posted on 2024-02-23

1066 Repolarisation-relaxation dyscoupling and TRPA1 activation permit systolic mechano-arrhythmogenesis

Cameron, B. A.; Stoyek, M. R.; Greiner, J.; Peyronnet, R.; Kohl, P.; Quinn, T. A.

10.1101/2024.02.21.581489 — physiology — Posted on 2024-02-23

1067 Integrated multi-omics analysis of Klebsiella pneumoniae revealed the discrepancy in flavonoid effect against strain growth between Rutin and Luteolin

Wang, Z.; Shen, W.; Li, Y.; Wang, X.; Xu, G.; Yuan, X.; Tang, H.; Ma, N.; Zhong, X.; Wang, X.

10.1101/2024.02.20.581226 — bioinformatics — Posted on 2024-02-23

1068 Biomaterial Degradation Products affect Regenerating Glia Independently of Surface Properties

Pawelec, K.; Hix, J. M. L.; Shapiro, E.

10.1101/2024.02.20.581223 — bioengineering — Posted on 2024-02-23

1069 Prenatal VEGF Nano-Delivery Reverses Congenital Diaphragmatic Hernia-Associated Pulmonary Abnormalities

Loukogeorgakis, S.; Michielin, F.; Shibuya, S.; Al-Juffali, N.; Jimenez, J.; Allen-Hyttinen, J.; Eastwood, P.; Alhendi, A.; Davidson, J.; Naldi, E.; Maghsoudlou, P.; Tedeschi, A.; Khalaf, S.; Khabbush, A.; Plate, M.; Fachin, C.; Dos Santos Dias, A.; Sindhawani, N.; Scaglioni, D.; Xenakis, T.; Sebire, N.; Giomo, M.; Eaton, S.; Toelen, J.; Luni, C.; Pavan, P.; Carmeliet, P.; Russo, F.; Janes, S.; Nikolic, M.; Elvassore, N.; Deprest, J.; De Coppi, P.

10.1101/2024.02.20.581170 — bioengineering — Posted on 2024-02-23

1070 Analysis of Poly(methyl methacrylate) Hydrogel IntradermalIrritation Test

Racheal, C.

10.1101/2024.02.19.581046 — biochemistry — Posted on 2024-02-23

1071 Long read subcellular fractionation and sequencing reveals the translational fate of full length mRNA isoforms during neuronal differentiation

Ritter, A.; Draper, J. M.; Vollmers, C.; Sanford, J.

10.1101/2024.02.20.581280 — molecular biology — Posted on 2024-02-23

1072 Evolution and inhibition of the FIKK effector kinase family in P. falciparum

Belda, H.; Bradley, D.; Christodoulou, E.; Nofal, S. D.; Broncel, M.; Jones, D. A.; Davies, H.; Bertran, M. T.; Purkiss, A. G.; Ogrodowicz, R. W.; Joshi, D.; O'Reilly, N.; Walport, L.; Claessens, A.; Powell, A.; House, D.; Kjaer, S.; Landry, C. R.; Treeck, M.

10.1101/2024.02.22.581535 — microbiology — Posted on 2024-02-23

1073 Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast

Zhang, J.; Li, J.; Huang, J.; Xiang, X.; Li, R.; Zhai, Y.; Lin, S.; Liu, W.

10.1101/2024.02.20.581167 — neuroscience — Posted on 2024-02-23

1074 Local Delivery of Soluble Fractalkine (CX3CL1) Peptide Restore Ribbon Synapses After Noise-Induced Cochlear Synaptopathy

Manickam, V. N.; Maity, S.; Murali, S. V.; Gawande, D. Y.; Stothert, A. R.; Batalkina, L. V.; Cardona, A.; Kaur, T.

10.1101/2024.02.20.581182 — neuroscience — Posted on 2024-02-23

1075 Effects of head-only exposure to 900 MHz GSM electromagnetic fields in rats : changes in neuronal activity as revealed by c-Fos imaging without concomitant cognitive impairments

Bontempi, B.; Leveque, P.; Dubreuil, D.; Jay, T.; EDELINE, J.-M.

10.1101/2024.02.20.581017 — neuroscience — Posted on 2024-02-23

1076 Estradiol elicits distinct firing patterns in arcuate nucleus kisspeptin neurons of females through altering ion channel conductances

Qiu, J.; Voliotis, M.; Bosch, M. A.; Li, X. F.; Zweifel, L. S.; Tsaneva-Atanasova, K.; O'Byrne, K.; Ronnekleiv, O. K.; Kelly, M. J.

10.1101/2024.02.20.581121 — neuroscience — Posted on 2024-02-23

1077 Genetic barcodes for ash (Fraxinus) species and generation of new wide hybrids

Plumb, W.; Kelly, L.; Mullender, J.; Powell, R.; Gorriz, M. N.; Carey, D.; Mason, M.; Crowther, W.; Koch, J.; Douglas, G.; Buggs, R.

10.1101/2024.02.19.581010 — plant biology — Posted on 2024-02-23

1078 Skeletal Muscle Satellite Cells Co-Opt the Tenogenic Gene Scleraxis to Instruct Regeneration

Bai, Y.; Harvey, T.; Bilyou, C.; Hu, M.; Fan, C.-M.

10.1101/2023.12.10.570982 — developmental biology — Posted on 2024-02-23

1079 Interpretable deep learning reveals the sequence rules of Hippo signaling

Dalal, K.; McAnany, C.; Weilert, M.; McKinney, M. C.; Krueger, S.; Zeitlinger, J.

10.1101/2024.02.22.580842 — genomics — Posted on 2024-02-23

1080 High or Low Expectations: Expected intensity of action outcome is embedded in action ‎kinetics

Buaron, B.; Reznik, D.; Mukamel, R.

10.1101/2024.02.20.581162 — neuroscience — Posted on 2024-02-23

1081 Stomatal patterning is differently regulated in adaxial and abaxial epidermis in Arabidopsis

Jalakas, P.; Tulva, I.; Berzina, N. M.; Horak, H.

10.1101/2024.02.22.581564 — plant biology — Posted on 2024-02-23

1082 Evolutionary approaches predicted changes in transcription factors and cis-elements that associate with Kranz anatomy development in maize

Saji, A.; Bijukumar, G.; R, N.; Thakur, V.

10.1101/2024.02.22.581542 — plant biology — Posted on 2024-02-23

1083 New insights into the mechanisms of post-rubisco isotope fractionation from combined analysis of intramolecular 13C and deuterium abundances in Pinus nigra tree-ring glucose

Wieloch, T.; Holloway-Phillips, M.; Yu, J.; Niittyla, T.

10.1101/2024.02.21.581384 — plant biology — Posted on 2024-02-23

1084 Agrobacterium-mediated Cuscuta campestris transformation as a tool for understanding plant-plant interactions

Adhikari, S.; Mudalige, A.; Phillips, L.; Lee, H.; Bernal, V.; Gruszewski, H.; Westwood, J.; Park, S.-Y.

10.1101/2024.02.23.581736 — plant biology — Posted on 2024-02-23

1085 Photoreceptor-induced LHL4 protects photosystem II in Chlamydomonas reinhardtii

Dannay, M.; Bertin, C.; Cavallari, E.; Albanese, P.; Tolleter, D.; Giustini, C.; Menneteau, M.; Brugiere, S.; Coute, Y.; Finazzi, G.; Demarsy, E.; Ulm, R.; Allorent, G.

10.1101/2024.02.23.581703 — plant biology — Posted on 2024-02-23

1086 Role of PLK1 in the epigenetic maintenance of centromeres

Conti, D.; Esposito Verza, A.; Pesenti, M. E.; Cmentowski, V.; Vetter, I. R.; Pan, D.; Musacchio, A.

10.1101/2024.02.23.581696 — cell biology — Posted on 2024-02-23

1087 Molecular and Cellular Mechanisms of Teneurin Signaling in Synaptic Partner Matching

Xu, C.; Li, Z.; Lyu, C.; Hu, Y.; McLaughlin, C.; Wong, K. K. L.; Xie, Q.; Luginbuhl, D. J.; Li, H.; Udeshi, N.; Svinkina, T.; Mani, D. R.; Carr, S. A.; Han, S.; Li, T.; Li, Y.; Guajardo, R.; Ting, A. Y.; Li, J.; Luo, L.

10.1101/2024.02.23.581689 — neuroscience — Posted on 2024-02-23

1088 Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons

Domingues, A. V.; Carvalho, T. T. A.; Martins, G. J.; Correia, R.; Coimbra, B.; Goncalves, R.; Wezik, M.; Gaspar, R.; Pinto, L.; Sousa, N.; Costa, R. M.; Soares-Cunha, C.; Rodrigues, A. J.

10.1101/2024.02.22.581563 — neuroscience — Posted on 2024-02-23

1089 Differential functions of the dorsal and intermediate regions of the hippocampus for optimal goal-directed navigation in VR space

Hwang, H.; Jin, S.-W.; Lee, I.

10.1101/2024.02.21.581413 — neuroscience — Posted on 2024-02-23

1090 A chromatic feature detector in the retina signals visual context changes

Hoefling, L.; Szatko, K. P.; Behrens, C.; Qiu, Y.; Deng, Y.; Klindt, D. A.; Jessen, Z.; Schwartz, G. S.; Bethge, M.; Berens, P.; Franke, K.; Ecker, A. S.; Euler, T.

10.1101/2022.11.30.518492 — neuroscience — Posted on 2024-02-23

1091 The ZmHSF20-ZmHSF4-ZmCesA2 module regulates heat stress tolerance in maize

Li, Z.; Li, Z.; Ji, Y.; Wang, C.; Wang, S.; Shi, Y.; Le, J.; Zhang, M.

10.1101/2024.02.21.581499 — plant biology — Posted on 2024-02-23

1092 A planar neuromuscular controller to simulate compensation strategies in the sit-to-walk movement.

van der Kruk, E.; Geijtenbeek, T.

10.1101/2023.11.24.568552 — bioengineering — Posted on 2024-02-23

1093 Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike

Oliveira, A. S. F.; Kearns, F. L.; Rosenfeld, M. A.; Casalino, L. F.; Berger, I.; Schaffitzel, C.; Davidson, A. D.; Amaro, R. E.; Mulholland, A. J.

10.1101/2023.11.06.565757 — biochemistry — Posted on 2024-02-23

1094 Gene Therapy Mediates Therapeutic Improvement in Cardiac Hypertrophy and Survival in a Murine Model of MYBPC3-Associated Cardiomyopathy

Lombardi, L. M.; Greer-Short, A.; Greenwood, A.; Leon, E. C.; Qureshi, T. N.; von Kraut, K.; Wong, J.; Reid, C. A.; Cheng, Z.; Easter, E.; Yang, J.; Ho, J.; Steltzer, S.; Budan, A.; Cho, M.; Feathers, C.; Chung, T. W.; Rodriguez, N.; Jones, S.; Alleyne-Levy, C.; Liu, J.; Jing, F.; Prince, W. S.; Lin, J.; Ivey, K. N.; Tingley, W. G.; Hoey, T.

10.1101/2024.02.19.581102 — genetics — Posted on 2024-02-23

1095 MaizeCODE reveals bi-directionally expressed enhancers that harbor molecular signatures of maize domestication.

Cahn, J.; Regulski, M.; Lynn, J.; Ernst, E.; de Santis Alves, C.; Ramakrishnan, S.; Chougule, K.; Wei, S.; Lu, Z.; Xu, X.; Drenkow, J.; Kramer, M.; Seetharam, A.; Hufford, M. B.; McCombie, W. R.; Ware, D.; Jackson, D.; Schatz, M. C.; Gingeras, T. R.; Martienssen, R. A.

10.1101/2024.02.22.581585 — plant biology — Posted on 2024-02-23

1096 Genotypic variation in blueberry flower morphology and nectar reward content affects pollinator attraction in a diverse breeding population

Cromie, J.; Ternest, J. J.; Komatz, A. P.; Adunola, P. M.; Azevedo, C.; Mallinger, R. E.; Munoz, P. R.

10.1101/2024.02.22.581568 — plant biology — Posted on 2024-02-23

1097 Ubiquitin-mediated stabilization of SlPsbS regulates low night temperature tolerance in tomatoes

Lu, J.; Yu, J.; Liu, P.; Gu, J.; Chen, Y.; Zhang, T.; Li, J.; Wang, T.; Yang, W.; Lin, R.; Wang, F.; Qi, M.; Li, T.; Liu, Y.

10.1101/2024.02.21.581502 — plant biology — Posted on 2024-02-23

1098 Exploring the Viral Landscape of Saffron through Metatranscriptomic Analysis

Martinez-Fajardo, C.; Navarro-Simarro, P.; Morote, L.; Rubio-Moraga, A.; Mondejar-Lopez, M.; Niza, E.; Argandona, J.; Ahrazem, O.; Gomez-Gomez, L.; Lopez-Jimenez, A. J.

10.1101/2024.02.22.581521 — plant biology — Posted on 2024-02-23

1099 Influence of plant defense signaling and innate insect metabolic differences to the overall performance of fall armyworm (Spodoptera frugiperda) corn and rice strains on maize as a host

Israni, B.; Haenniger, S.; Raguschke, B.; Reichelt, M.; Gershenzon, J.; Vassao, D. G.

10.1101/2023.12.07.570551 — ecology — Posted on 2024-02-23

1100 Design of artificial molecular motor inheriting directionality and scalability.

Ito, K. I.; Sato, Y.; Toyabe, S.

10.1101/2023.07.19.549658 — biophysics — Posted on 2024-02-23

1101 Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

Elofsson, A.; Han, L.; Bianchi, E.; Wright, G. J.; Jovine, L.

10.1101/2023.07.27.550195 — biophysics — Posted on 2024-02-23

1102 Microencapsulation of mesenchymal stromal cells in covalent alginate hydrogels for cell therapy

Ambrosino, M.; Nativel, F.; Boyer, C.; Lagneau, N.; Loll, F.; Halgand, B.; Djouad, F.; Renard, D.; Tessier, A.; Guicheux, J.; Delplace, V.; Le Visage, C.

10.1101/2023.11.27.568852 — bioengineering — Posted on 2024-02-23

1103 Pleiotropic effects of a recessive COL1A2 mutation occurring in a mouse model of severe osteogenesis imperfecta

Corcelli, M.; Sagar, R.; Petzendorfer, E.; Hasan, M. M.; de Vries, H. I.; van Dijk, F. S.; David, A. L.; Guillot, P. V.

10.1101/2024.02.15.580510 — genetics — Posted on 2024-02-23

1104 Synchronous ensembles of hippocampal CA1 pyramidal neurons associated with theta but not ripple oscillations during novel exploration

Chen, E.-L.; Chen, T.-W.; Schreiter, E. R.; Lin, B.-J.

10.1101/2024.02.07.579313 — neuroscience — Posted on 2024-02-23

1105 Targeting a specific motor control process reveals an age-related compensation that adapts movement to gravity environment

MATHIEU, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.

10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-02-23

1106 Theta and alpha oscillations in human hippocampus and medial parietal cortex support the formation of location-based representations

Satish, A.; Keller, V.; Raza, S.; Fitzpatrick, S.; Horner, A. J.

10.1101/2023.10.18.562859 — neuroscience — Posted on 2024-02-23

1107 No Replication of Direct Neuronal Activity-related (DIANA) fMRI in Anesthetized Mice

Choi, S.-H.; Im, G. H.; Choi, S.; Yu, X.; Bandettini, P. A.; Menon, R. S.; Kim, S.-G.

10.1101/2023.05.26.542419 — neuroscience — Posted on 2024-02-23

1108 Intermittent fasting promotes type 3 innate lymphoid cells secreting IL-22 contributing to the beigeing of white adipose tissue

Chen, H.; Sun, L.; Feng, L.; Han, X.; Zhang, Y.; Zhai, W.; Zhang, Z.; Mulholland, M.; Zhang, W.; Yin, Y.

10.1101/2023.08.29.555436 — physiology — Posted on 2024-02-23

1109 A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A

Sabbarini, I.; Reif, D.; Park, K.; McQuown, A.; Nelliat, A.; Trejtnar, C.; Dotsch, V.; Shakhnovich, E.; Murray, A.; Denic, V.

10.1101/2024.02.22.581594 — biochemistry — Posted on 2024-02-23

1110 Improved inference of population histories by integrating genomic and epigenomic data

Sellinger, T. P. P.; Johannes, F.; Tellier, A.

10.1101/2023.04.02.535252 — evolutionary biology — Posted on 2024-02-23

1111 Phenotypic plasticity in response to growth temperature far outweighs other environmental and genetic causes of variation in an alpine plant

Arnold, P. A.; Wang, S.; Notarnicola, R. F.; Nicotra, A. B.; Kruuk, L. E. B.

10.1101/2024.02.20.581287 — ecology — Posted on 2024-02-23

1112 Ca2+-sensor ALG-2 engages ESCRTs to enhance lysosomal membrane resilience to osmotic stress

Chen, W.; Motsinger, M. M.; Li, J.; Bohannon, K. P.; Hanson, P. I.

10.1101/2024.02.04.578682 — cell biology — Posted on 2024-02-23

1113 Functional identification of soluble uric acid as an endogenous inhibitor of CD38

Wen, S.; Arakawa, H.; Yokoyama, S.; Shirasaka, Y.; Higashida, H.; Tamai, I.

10.1101/2023.06.03.543541 — immunology — Posted on 2024-02-23

1114 Light-Guided Rabies Virus Tracing for Neural Circuit Analysis

Zhang, S.; Ma, Y.; Ngamkanjanarat, W.; Takahashi, S.; Gibbs, D.; Coleman, T.; Doan, S.; Kyriakakis, P.

10.1101/2023.03.04.531104 — neuroscience — Posted on 2024-02-23

1115 Targeted-Neuroinflammation Mitigation Using Inflammasome-Inhibiting Nanoligomers is Therapeutic in Experimental Autoimmune Encephalomyelitis (EAE) Mouse Model

Sharma, S.; Risen, S.; Gilberto, V.; Boland, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.

10.1101/2024.01.11.575262 — neuroscience — Posted on 2024-02-23

1116 Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky

Franke, K.; Cai, C.; Ponder, K.; Fu, J.; Sokoloski, S.; Berens, P.; Tolias, A. S.

10.1101/2023.06.01.543054 — neuroscience — Posted on 2024-02-23

1117 Transcriptomes Often Resemble Biological Aging Upon Perturbation

Stoeger, T.

10.1101/2023.03.28.534472 — systems biology — Posted on 2024-02-23

1118 Graph Attention Site Prediction (GrASP): Identifying Druggable Binding Sites Using Graph Neural Networks with Attention

Smith, Z.; Strobel, M.; Vani, B.; Tiwary, P.

10.1101/2023.07.25.550565 — biophysics — Posted on 2024-02-23

1119 Harmonizing and integrating the NCI Genomic Data Commons through accessible, interactive, and cloud-enabled workflows

Hung, L.-H.; Fukuda, B.; Schmitz, R.; Hoang, V.; Lloyd, W.; Yeung, K. Y.

10.1101/2022.08.11.503660 — bioinformatics — Posted on 2024-02-23

1120 Generic rules of lumen nucleation and fusion in epithelial organoids

Lu, L.; Fuji, K.; Guyomar, T.; Lieb, M.; Tanida, S.; Nonomura, M.; Hiraiwa, T.; Alcheikh, Y.; Yennek, S.; Petzold, H.; Martin-Lemaitre, C.; Grapin-Botton, A.; Honigmann, A.; Sano, M.; Riveline, D.

10.1101/2024.02.20.581158 — biophysics — Posted on 2024-02-23

1121 Transcription factor-mediated generation of dopaminergic neurons from human iPSCs: a comparison of methods

Basak, I.; McDonald, K. O.; Lyons, N. M. A.; Schoderboeck, L.; Hughes, S. M.

10.1101/2024.02.22.581485 — neuroscience — Posted on 2024-02-22

1122 Effects of childhood hearing loss on the subcortical and cortical representation of speech

Calcus, A.; Rosen, S.

10.1101/2024.02.22.581639 — physiology — Posted on 2024-02-22

1123 Modularity in the evolution of visual signals associated with aggressive displays

Fialko, K.; Price, T. D.

10.1101/2024.02.22.581650 — animal behavior and cognition — Posted on 2024-02-22

1124 Charting the Cannabis plant chemical space with computational metabolomics

Myoli, A.; Choene, M.; Kappo, A. P.; Madala, N. E.; van der Hooft, J. J. J.; Tugizimana, F.

10.1101/2024.02.21.581363 — systems biology — Posted on 2024-02-22

1125 Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe

Byerly, P.; von Thaden, A.; Leushkin, E.; Hilgers, L.; Liu, S.; Winter, S.; Schell, T.; Buechner, S.; Meinig, H.; Lang, J.; Famira-Parcsetich, E.; Stubbe, S.; Gerheim, C.; Ben-Hamadou, A.; Bolz, H.; Betz, C.; Greve, C.; Mouton, A.; Bertolino, S.; Verbeylen, G.; Briner, T.; Vinciguerra, L.; Mueller, S.; Nowack, C.; Hiller, M.

10.1101/2024.02.21.581346 — genomics — Posted on 2024-02-22

1126 Gene expression differences associated with intrinsic hindfoot muscle loss in the jerboa, Jaculus jaculus

Tran, M. P.; Ochoa Reyes, D.; Weitzel, A. J.; Saxena, A.; Hiller, M.; Cooper, K. L.

10.1101/2024.02.20.581295 — developmental biology — Posted on 2024-02-22

1127 Unraveling the Role of Urea Hydrolysis in Salt Stress Response during Seed Germination and Seedling Growth in Arabidopsis thaliana

Bu, Y.; Dong, X.; Zhang, R.; Shen, X.; Liu, Y.; Shu Wang, S.; Takano, T.; Liu, S.

10.1101/2024.02.20.581165 — plant biology — Posted on 2024-02-22

1128 Multi-tissue transition of A-to-I RNA editing pattern and its regulatory relevance in transcription, splicing, and translation during development

Pan, J.-Q.; Pan, X.-B.; Liu, Y.-S.; Jin, Y.-Y.; Chen, J.-H.

10.1101/2024.02.21.581478 — genomics — Posted on 2024-02-22

1129 Keetia nodulosa sp. nov. (Rubiaceae - Vanguerieae) of West - Central Africa: bacterial leaf nodulation discovered in a fourth genus and tribe of Rubiaceae.

Cheek, M.; Onana, J. M.

10.1101/2024.02.20.581267 — plant biology — Posted on 2024-02-22

1130 Molecular confirmation of Anopheles stephensi in the Al Hudaydah Governorate, Yemen, 2021-2022.

Assada, M.; Al-Hadi, M.; Esmail, M. A.; Al-Jurban, J.; Alkawri, A.; Shamsan, A.; Gomein, P.; Samake, J. N.; Aljasari, A.; Awash, A. A.; Al Eryani, S. M.; Carter, T. E.

10.1101/2024.02.22.577782 — genetics — Posted on 2024-02-22

1131 Blockade of Interleukin-6 (IL-6) Signaling in Dedifferentiated Liposarcoma (DDLPS) Decreases Mouse Double Minute 2 (MDM2) Oncogenicity via Alternative Splicing

Zewdu, A.; Braggio, D.; Lopez, G.; Batte, K.; Khurshid, S.; Costas de Faria, F.; Bid, H.; Koller, D.; Casadei, L.; Ladner, K.; Wang, D.; Grignol, V.; Iwenofu, O. H.; Chandler, D.; Guttridge, D.; Pollock, R.

10.1101/2024.02.21.581397 — molecular biology — Posted on 2024-02-22

1132 The Apurinic/Apyrimidinic Endodeoxyribonuclease 1 is an RNA G-quadruplex binding protein and regulates miR-92b expression in cancer cells

Bellina, A.; Malfatti, M. C.; Salgado, G.; Fleming, A. M.; Antoniali, G.; Gualandi, N.; La Manna, S.; Marasco, D.; Dassi, E.; Burrows, C. J.; Tell, G.

10.1101/2024.02.22.581538 — molecular biology — Posted on 2024-02-22

1133 Dose-response functional and transcriptomic effects of follicle-stimulating hormone on ex vivo mouse folliculogenesis

Zhan, T.; Zhang, J.; Zhang, Y.; Zhao, Q.; Chemerinski, A.; Douglas, N. C.; Zhang, Q.; Xiao, S.

10.1101/2024.02.20.581188 — molecular biology — Posted on 2024-02-22

1134 Simultaneous protein and RNA analysis in single extracellular vesicles, including viruses: SPIRFISH

Troyer, Z.; Gololobova, O.; Koppula, A.; Liao, Z.; Horns, F.; Elowitz, M. B.; Tosar, J. P.; Batish, M.; Witwer, K. W.

10.1101/2024.02.21.581401 — molecular biology — Posted on 2024-02-22

1135 Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease

Weiss, L.; Carrer, M.; Shmara, A.; Cheng, C.; Yin, H.; Ta, L.; Boock, V.; Fazeli, Y.; Chang, M.; Paguio, M.; Lee, J.; Yu, H.; Martin, A.; Raben, N.; Weiss, J.; Grossman, T.; Jafar-nejad, P.; Kimonis, V.

10.1101/2024.02.22.580414 — molecular biology — Posted on 2024-02-22

1136 Catabolism of germinant amino acids is required to prevent premature spore germination in Bacillus subtilis

Kasu, I. R.; Reyes-Matte, O.; Bonive-Boscan, A.; Derman, A. I.; Lopez Garrido, J.

10.1101/2024.02.22.581590 — microbiology — Posted on 2024-02-22

1137 Human MX1 induces the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

McKellar, J.; Garcia de Gracia, F.; Aube, C.; Chaves Valadao, A. L.; Tauziet, M.; Arnaud-Arnould, M.; Rebendenne, A.; Neyret, A.; Labaronne, E.; Ricci, E. P.; Delaval, B.; Gaudin, R.; Naffakh, N.; Gallois-Montbrun, S.; Moncorge, O.; Goujon, C.

10.1101/2024.02.22.581565 — microbiology — Posted on 2024-02-22

1138 Development of radial frequency pattern perception in macaque monkeys

Rodriguez Deliz, C. L.; Lee, G.; Bushnell, B.; Majaj, N. J.; Movshon, J. A.; Kiorpes, L.

10.1101/2024.02.21.581393 — neuroscience — Posted on 2024-02-22

1139 Sensory perception of fluctuating light in Arabidopsis

Belmonte, A.; Tissot, N.; Rabinovich, A.; Ploschuk, E.; Crocco, C.; Ulm, R.; Casal, J. J.

10.1101/2024.02.21.581400 — plant biology — Posted on 2024-02-22

1140 The polyamine transporter ATP13A3 mediates DFMO-induced polyamine uptake in neuroblastoma

Azfar, M.; Gao, W.; Van den Haute, C.; Xiao, L.; Karsa, M.; Pandher, R.; Ronca, E.; Bongers, A.; Karsa, A.; Spurling, D.; Guo, X.; Mayoh, C.; Burns, M. R.; Verhelst, S. H. L.; Norris, M. D.; Haber, M.; Vangheluwe, P.; Somers, K.

10.1101/2024.02.20.581161 — cancer biology — Posted on 2024-02-22

1141 In-cell structure and snapshots of copia retrotransposons in intact tissue by cryo-electron tomography

Klumpe, S.; Senti, K. A.; Beck, F.; Sachweh, J.; Hampoelz, B.; Ronchi, P.; Yeroslaviz, A.; Briggs, J.; Brennecke, J.; Beck, M.; Plitzko, J. M.

10.1101/2024.02.21.581285 — biophysics — Posted on 2024-02-22

1142 A tractable tree distribution parameterized by clade probabilities and its application to Bayesian phylogenetic point estimation

Berling, L.; Klawitter, J.; Bouckaert, R.; Xie, D.; Gavryushkin, A.; Drummond, A.

10.1101/2024.02.20.581316 — bioinformatics — Posted on 2024-02-22

1143 Secondary metabolite biosynthetic gene clusters and their genomic localization in the fungal genus Aspergillus

Zhang, X.; Leahy, I.; Collemare, J.; Seidl, M. F.

10.1101/2024.02.20.581327 — bioinformatics — Posted on 2024-02-22

1144 In-situ microscopy-assisted meniscus-guided coating for highly sensitive reduced graphene oxide-based nanocomposite biosensor

Kim, S. Y.; Kim, M.; Lee, J.-C.; Jeon, B.; Kim, H.; Choi, S. Q.; Oh, B.; Kang, H.; Kim, H.-R.; Park, S.

10.1101/2024.02.20.580941 — bioengineering — Posted on 2024-02-22

1145 Trapped in translocation: Stalling of XPD on a crosslinked DNA substrate

Kuper, J.; Hove, T.; Maidl, S.; Sauer, F.; Kempf, M.; Greiter, E.; Neitz, H.; Hoebartner, C.; Kisker, C.

10.1101/2024.02.20.581127 — biochemistry — Posted on 2024-02-22

1146 Arabidopsis Gluconolactonase, the First Enzyme Involved in Ascorbate Biosynthesis Localized in the Chloroplast Protects Plants from Light Stress.

Yactayo-Chang, J. P.; Nepal, N.; Aboobucker, S. I.; Medina-Jimenez, K.; Wilkie, A.; Teoh, T. K.; Wilson, G. A.; LORENCE, A.

10.1101/2024.02.22.578673 — biochemistry — Posted on 2024-02-22

1147 C. elegans LIN-66 mediates EIF-3.G-dependent protein translation via a cold-shock domain

Jin, Y.; Blazie, S. M.; Fortunati, D.; Zhao, Y.

10.1101/2024.02.20.581241 — genetics — Posted on 2024-02-22

1148 EasyOmics-A graphical interface for population-scale omics data association, integration and visualization

han, y.; zan, y.

10.1101/2024.02.20.581292 — genetics — Posted on 2024-02-22

1149 Modeling heterogeneity in single-cell perturbation states enhances detection of response eQTLs

Raychaudhuri, S.; Valencia, C.; Nathan, A.; Kang, J. B.; Rumker, L.; Lee, H.

10.1101/2024.02.20.581100 — genetics — Posted on 2024-02-22

1150 Land-use impacts on plant functional diversity throughout Europe

Rosa, F.; Hellweg, S.; Pfister, S.; van Bodegom, P.; Biurrun, I.; Boch, S.; Byun, C.; Chytry, M.; Custerevska, R.; Dalle Fratte, M.; Damasceno, G.; Dolezal, J.; Dziuba, T.; Garbolino, E.; Herault, B.; Lenoir, J.; Martin-Fores, I.; Niinemets, U.; Ozinga, W. A.; Penuelas, J.; Peyre, G.; Sabatini, F. M.; Schrodt, F.; Uogintas, D.; Scherer, L.

10.1101/2024.02.21.580945 — ecology — Posted on 2024-02-22

1151 enmpa: An R package for ecological niche modeling using presence-absence data and generalized linear models

Arias-Giraldo, L. F.; Cobos, M. E.

10.1101/2024.02.20.581032 — ecology — Posted on 2024-02-22

1152 Phenotypic plasticity in response to growth temperature far outweighs other environmental and genetic causes of variation in an alpine plant

Arnold, P. A.; Wang, S.; Notarnicola, R. F.; Nicotra, A. B.; Kruuk, L. E. B.

10.1101/2024.02.20.581287 — ecology — Posted on 2024-02-22

1153 Using serosurveys to optimize surveillance for zoonotic pathogens

Clancey, E.; Nuismer, S. L.; Seifert, S. N.

10.1101/2024.02.22.581274 — ecology — Posted on 2024-02-22

1154 RNA-MobiSeq: Deep mutational scanning and mobility-based selection for RNA structure inference

Tang, J.; Shi, Y.; Zhang, Z.; Luo, D.; Zhan, J.; Zhou, Y.

10.1101/2024.02.21.581340 — molecular biology — Posted on 2024-02-22

1155 A novel truncated CHAP modular endolysin, CHAPSAP26-161, that lyses Staphylococcus aureus, Acinetobacter baumannii, and Clostridioides difficile

Choi, Y.-j.; Kim, S.; Dahal, R. H.; Kim, J.

10.1101/2024.02.22.581501 — microbiology — Posted on 2024-02-22

1156 The assembly and efflux processes revealed by in situ structures of the ABC-type tripartite pump MacAB-TolC

Huo, T.; Yu, Z.; Cao, J.-L.; Shi, X.; wang, z.

10.1101/2024.02.22.581608 — microbiology — Posted on 2024-02-22

1157 Protein aggregation is a consequence of the dormancy-inducing membrane toxin TisB in Escherichia coli

Leinberger, F. H.; Cassidy, L.; Edelmann, D.; Schmid, N. E.; Blumenkamp, P.; Schmidt, S.; Natriashvili, A.; Ulbrich, M. H.; Tholey, A.; Koch, H.-G.; Berghoff, B. A.

10.1101/2024.02.22.581605 — microbiology — Posted on 2024-02-22

1158 Spatial analysis reveals combinative role for natural killer and CD8 T cells in antitumor immunity despite profound MHC class I loss in non-small cell lung cancer

Wessel, R. E.; Ageeb, N.; Obeid, J. M.; Mauldin, I.; Goundry, K. A.; Hossain, M.; Lehman, C.; Gentzler, R. D.; Wages, N. A.; Slingluff, C. L.; Bullock, T. N. J.; Dolatshahi, S.; Brown, M. G.

10.1101/2024.02.20.581048 — immunology — Posted on 2024-02-22

1159 Human Alveolar and Monocyte-derived Human Macrophage Responses to Mycobacterium tuberculosis

Campo, M.; Dill-McFarland, K.; Peterson, G.; Benson, B.; Skerrett, S.; Hawn, T.

10.1101/2024.02.20.581265 — immunology — Posted on 2024-02-22

1160 CD4+ T Cell Depletion Before Primary Dengue and/or Secondary Zika Infection Reveals Mechanistic Correlates of Antibody Functionality in Rhesus Macaques.

Serrano-Collazo, C.; Miranda, A. M.; Cruz, L. A.; Henein, S.; Sanchez-Rosado, M. R.; Alvarez, L.; Arana, T.; Martinez, M. I.; Roman, C.; Burgos, A.; de Silva, A. M.; Sariol, C. A.

10.1101/2024.02.22.580962 — immunology — Posted on 2024-02-22

1161 Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

Nelson, A. J.; Bruna, T. K.; Beach, J. R.; Sojka, D. K.; Wu, Y. L.

10.1101/2024.02.20.581262 — immunology — Posted on 2024-02-22

1162 Recurrent neural networks as neuro-computational models of human speech recognition

Brodbeck, C.; Hannagan, T.; Magnuson, J. S.

10.1101/2024.02.20.580731 — neuroscience — Posted on 2024-02-22

1163 Local desensitization to dopamine devalues recurring behavior

Miner, L. E.; Gautham, A. K.; Crickmore, M. A.

10.1101/2024.02.20.581276 — neuroscience — Posted on 2024-02-22

1164 Graspable foods and tools elicit similar responses in visual cortex

Ritchie, J. B.; Andrews, S. B.; Vaziri-Pashkam, M.; Baker, C. I.

10.1101/2024.02.20.581258 — neuroscience — Posted on 2024-02-22

1165 Asiatic acid improves mitochondrial function, activates antioxidant response in the mouse brain and improves cognitive function in beta-amyloid overexpressing mice.

Varada, S.; Chamberlin, S. R.; Bui, L.; Brandes, M. S.; Gladen-Kolarksy, N.; Harris, C. J.; Hack, W.; Brumbach, B. H.; Quinn, J. F.; Gray, N. E.

10.1101/2024.02.21.581270 — neuroscience — Posted on 2024-02-22

1166 Microglia are not required for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism

Profaci, C. P.; Harvey, S. S.; Bajc, K.; Zhang, T. Z.; Zhang, A. Z.; Nemec, K. M.; McKinsey, G. L.; Longworth, A.; McMullen, T. P.; Arnold, T. D.; Lawson, D. A.; Bennett, F. C.; Davalos, D.; Daneman, R.

10.1101/2024.02.20.580754 — neuroscience — Posted on 2024-02-22

1167 Pangenome mining of the Streptomyces genus redefines their biosynthetic potential

Mohie, O. S.; Jorgensen, T. S.; Booth, T. J.; Charusanti, P.; Phaneuf, P. V.; Weber, T.; Palsson, B. O.

10.1101/2024.02.20.581055 — systems biology — Posted on 2024-02-22

1168 Cohort-specific Boolean models highlight different regulatory modules during Parkinson's disease progression

Hemedan, A. A.; Satagopam, V. P.; Schneider, R.; Ostaszewski, M.

10.1101/2024.02.20.581152 — systems biology — Posted on 2024-02-22

1169 Efficient cloning of genes for wheat yield component traits from QTLs via sequencing of the RIL population

Zhang, M.; Han, X.; Wang, H.; Sun, J.; Guo, B.; Gao, M.; Xu, H.; Zhang, G.; Li, H.; Cao, X.; Li, N.; Xu, Y.; Wu, Q.; Wang, C.; Zhang, G.; Yuan, Y.; Man, J.; Pu, Y.; Lv, G.; Qu, C.; Sun, J.; Cheng, X.; Dong, X.; Kong, F.; Zhao, Y.; An, Y.; Yuan, Y.; Guo, Y.; Li, S.

10.1101/2024.02.22.574000 — plant biology — Posted on 2024-02-22

1170 Age-dependent miR156-targeted SPLs are required for extrafloral nectary development in Passiflora spp.

Soares, J. R.; Robledo, K. J. M.; Souza, V. C.; Dias, L. L. L.; Silva, L. A. S.; Silveira, E. C.; Souza, C. d. S.; Sousa, E. S.; Sodrzeieski, P. A.; Sarmiento, Y. C. G.; Matos, E. M.; Falcao, T. C. d. A.; Fialho, L. d. S.; Guimaraes, V. M.; Viccini, L. F.; Pierdona, F. G.; Romanel, E.; Fouracre, J.; Otoni, W. C.; Nogueira, F.

10.1101/2024.02.20.581215 — plant biology — Posted on 2024-02-22

1171 Rapid, direct, and sequence-specific identification of RNA viruses in various crop plants using CRISPR/Cas13a

Hak, H.; Ostendorp, S.; Reza, A.; Ishgur Greenberg, S.; Pines, G.; Kehr, J.; Spiegelman, Z.

10.1101/2024.02.22.581525 — plant biology — Posted on 2024-02-22

1172 PiggyBac Transposase Mediated Inducible Trophoblast-specific Knockdown of Mechanistic Target of Rapamycin in Mice Decreases Placental Nutrient Transport and Inhibits Fetal Growth.

Rosario, F. J.; Urschitz, J.; Razavy, H.; Elston, M.; Powell, T. L.; Jansson, T.

10.1101/2024.02.20.581180 — physiology — Posted on 2024-02-22

1173 The wide spectrum anti-inflammatory activity of andrographolide in comparison to NSAIDs: a promising therapeutic compound against the cytokine storm

Low, M.; Suresh, H.; Zhou, X.; Bhuyan, D. J.; Alsherbiny, M. A.; Khoo, C.; Münch, G.; Li, C. G.

10.1101/2024.02.21.581396 — pharmacology and toxicology — Posted on 2024-02-22

1174 CDKN1B (p27kip1) enhances drug tolerant persister CTCs by restricting polyploidy following mitotic inhibitors.

Horwitz, E.; Dubash, T. D.; Szabolcs, A.; Wittner, B. S.; Kreuzer, J.; Morris, R.; Bardia, A.; Chirn, B.; Wiley, D.; Che, D.; Russel, H. C.; Lopez, X. I. H.; Fox, D. B.; Antmen, E.; Ting, D. T.; Haas, W.; Sade-Feldman, M.; Maheswaran, S.; Haber, D. A.

10.1101/2024.02.20.581202 — cancer biology — Posted on 2024-02-22

1175 Time Resolved Inspection of Ionizable-Lipid Facilitated Lipid Nanoparticle Disintegration and Cargo Release at an Endosomal Membrane Mimic

Aliakbarinodehi, N.; Niederkofler, S.; Olsen, E.; Jing, Y.; Emilsson, G.; Sjoberg, M.; Agnarsson, B.; Lindfors, L.; Hook, F.

10.1101/2024.02.22.580934 — biophysics — Posted on 2024-02-22

1176 RhizoBindingSites v2.0 is a bioinformatic database of DNA motifs potentially involved in transcriptional regulation deduced from sites of the itself genome

Taboada-Castro, H.; Hernandez-Alvarez, A. J.; Castro-Mondragon, J. A.; Encarnacion-Guevara, S.

10.1101/2024.02.22.581308 — bioinformatics — Posted on 2024-02-22

1177 Nanobody-targeted conditional antimicrobial therapeutics

Ngambenjawong, C.; Ko, H.; Pishesha, N.; Ploegh, H. L.; Bhatia, S. N.

10.1101/2024.02.20.580917 — bioengineering — Posted on 2024-02-22

1178 Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species

Faria, R. L.; Prado, F. M.; Junqueira, H. C.; Fabiano, K. C.; Diniz, L. R.; Baptista, M. S.; Di Mascio, P.; Miyamoto, S.

10.1101/2024.02.22.581635 — biochemistry — Posted on 2024-02-22

1179 The MAP2Ks can use ADP to phosphorylate and activate their substrate MAPKs in vitro

Juyoux, P.; von Velsen, J.; Pellegrini, E.; Bowler, M. W.

10.1101/2024.02.22.581546 — biochemistry — Posted on 2024-02-22

1180 Coordination of cytochrome bc1 complex assembly at MICOS

Zerbes, R. M.; Colina-Tenorio, L.; Bohnert, M.; Peikert, C. D.; von der Malsburg, K.; Mehnert, C. S.; Perschil, I.; Klar, R.; van der Klei, I. J.; Oeljeklaus, S.; Warscheid, B.; Rampelt, H.; van der Laan, M.

10.1101/2024.02.22.580370 — biochemistry — Posted on 2024-02-22

1181 A ribosome-associating chaperone mediates GTP-driven vectorial folding of nascent eEF1A

Denic, V.; Sabbarini, I.; Reif, D.; Park, K.; McQuown, A.; Nelliat, A.; Trejtnar, C.; Dotsch, V.; Shakhnovich, E.; Murray, A.

10.1101/2024.02.22.581594 — biochemistry — Posted on 2024-02-22

1182 A genetically-encoded nanobody sensor reveals conformational diversity in beta-arrestins orchestrated by distinct seven transmembrane receptors

Sarma, P.; Markov, V. N.; Zaidi, N.; Dalal, A.; Mishra, S.; Yadav, M. K.; Mahajan, G.; Roy, N.; Miclea, P.; Lazar, J.; SHUKLA, A. K.

10.1101/2024.02.21.581355 — biochemistry — Posted on 2024-02-22

1183 Metabolic Quadrivalency in RSeT Human Embryonic Stem Cells

Chen, K. G.; Park, K.; Maric, D.; Johnson, K. R.; Robey, P. G.; Mallon, B. S.

10.1101/2024.02.21.581486 — biochemistry — Posted on 2024-02-22

1184 The evolution of reduced facilitation in a four-species bacterial community

Piccardi, P.; Ulrich, E.; Garcia-Garcera, M.; Di Martino, R.; Testa, S. E. A.; Mitri, S.

10.1101/2024.02.22.581583 — evolutionary biology — Posted on 2024-02-22

1185 Investigating the Evolution of Green Algae with a Large Transcriptomic Dataset

Ferranti, D. A.; Delwiche, C. F.

10.1101/2024.02.21.581324 — evolutionary biology — Posted on 2024-02-22

1186 Chromatin structure around long non-coding RNA (lncRNA) genes in Schistosoma mansoni gonads

de Carvalho Augusto, R.; Quack, T.; Grevelding, C. G.; Grunau, C.

10.1101/2024.02.22.581540 — molecular biology — Posted on 2024-02-22

1187 Mimivirus encodes an essential MC1-like non-histone architectural protein involved in DNA condensation

Sharma, D.; Coulibaly, F.; Kondabagil, K.

10.1101/2024.02.22.580433 — molecular biology — Posted on 2024-02-22

1188 Extracellular electron transfer genes expressed by candidate flocking bacteria in cable bacteria sediment

Lustermans, J. J.; Sereika, M.; Burdorf, L. D.; Albertsen, M.; Schramm, A.; Marshall, I. P.

10.1101/2024.02.22.581617 — microbiology — Posted on 2024-02-22

1189 The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures

Antunes, B.; Zanchi, C.; Maron, B.; Witzany, C.; Regoes, R. R.; Hayouka, Z.; Rolff, J.

10.1101/2024.02.22.581582 — microbiology — Posted on 2024-02-22

1190 Comparison of gnotobiotic communities reveals unexpected amino acid metabolism by the pre-weaning microbiome.

Lubin, J.-B.; Silverman, M. A.; Planet, P. J.

10.1101/2024.02.22.581588 — microbiology — Posted on 2024-02-22

1191 An efficient in vivo-inducible CRISPR interference system for group A Streptococcus genetic analysis and pathogenesis studies

Bjanes, E.; Stream, A.; Gibson, P. S.; Bravo, A. M.; Dahesh, S.; Baker, J. L.; Varble, A.; Nizet, V.; Veening, J.-W.

10.1101/2024.02.22.581527 — microbiology — Posted on 2024-02-22

1192 Unravelling the roadblocks to 1,2-propanediol biosynthesis in select solventogenic Clostridium species

Agyeman-Duah, E.; Kumar, S.; Ujor, V.

10.1101/2024.02.22.581430 — microbiology — Posted on 2024-02-22

1193 A handle on mass coincidence errors in de novo sequencing of antibodies by bottom-up proteomics

Schulte, D.; Snijder, J.

10.1101/2024.02.20.581155 — bioinformatics — Posted on 2024-02-22

1194 Automated high-throughput biological sex identification from archaeological human dental enamel using targeted proteomics

Koenig, C.; Bortel, P.; Paterson, R. S.; Rendl, B.; Madupe, P. P.; Troche, G. B.; Hermann, N. V.; Martinez de Pinillos, M.; Martinon-Torres, M.; Mularczyk, S.; Jorkov, M. L. S.; Gerner, C.; Kanz, F.; Martinez-Val, A.; Cappellini, E.; Olsen, J. V.

10.1101/2024.02.20.581140 — biochemistry — Posted on 2024-02-22

1195 Environmental and Historical Determinants of African Horse Sickness: Insights from Predictive Modeling

Kim, K.; Xu, T.; Kannan Villalan, A.; Chi, T.; Yu, X.; Jin, M.; Wu, R.; Ni, G.; Sui, S.; Wang, Z.; Wang, X.

10.1101/2024.02.20.581150 — ecology — Posted on 2024-02-22

1196 Food entrainment in mice leads to sex- and organ-specific responses in nutrient metabolism

Di Natale, M. R.; McQuade, R.; Hunne, B. L.; Koo, A.; Ringuet, M.; Coles, T.; Fothergill, L.; Furness, J. B.; Oparija-Rogenmozere, L.

10.1101/2024.02.20.580958 — molecular biology — Posted on 2024-02-22

1197 Mapping responses to focal injections of bicuculline in the lateral parafacial region identifies core regions for maximal generation of active expiration

Abad, A.; Prostebby, M.; Dickson, C. T.; Pagliardini, S.

10.1101/2023.11.17.567547 — neuroscience — Posted on 2024-02-22

1198 Maternal Immune Activation Alters Temporal Precision of Spike Generation of CA1 Pyramidal Neurons by Unbalancing GABAergic Inhibition in the Offspring

Griego, E.; Cerna, C.; Sollozo-Dupont, I.; Fuenzalida, M.; Galvan, E. J.

10.1101/2024.02.19.581109 — neuroscience — Posted on 2024-02-22

1199 Autonomic modulations to cardiac dynamics in response to affective touch: Differences between social touch and self-touch

Candia-Rivera, D.; Boehme, R.; Salamone, P. C.

10.1101/2024.02.20.581146 — neuroscience — Posted on 2024-02-22

1200 London taxi drivers exploit neighbourhood boundaries for hierarchical route planning

Griesbauer, E.-M.; Fernandez Velasco, P.; Coutrot, A.; Wiener, J. M.; Morley, J. G.; McNamee, D.; Manley, E.; Spiers, H. J.

10.1101/2024.02.20.581139 — neuroscience — Posted on 2024-02-22

1201 Busted: maternal modifiers of the triploid block involved in seed size control.

Akinmusola, R. Y.; Kilsby, H.; Wilkins, C.-A.; Cevik, V.; Scott, R.; Doughty, J.

10.1101/2024.02.20.581014 — plant biology — Posted on 2024-02-22

1202 PathEX: Make Good Choice for Whole Slide Image Extraction

Yang, X.; Zhang, R.; Yang, Y.; Zhang, Y.; Chen, K.

10.1101/2024.02.20.581147 — pathology — Posted on 2024-02-22

1203 The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

Borrego, B.; Alonso, C.; Moreno, S.; de la Losa, N.; Sanchez-Cordon, P. J.; Brun, A.

10.1101/2024.02.20.581149 — pathology — Posted on 2024-02-22

1204 Enhanced cardiac mitochondrial biogenesis by nitro-oleic acid remedies diastolic dysfunction in a mouse model of heart failure with preserved ejection fraction

Mueller, M.; Schubert, T.; Welke, C.; Schulz, T. J.; Patschkowski, T.; Maske, T.; Lengenfelder, L. A.; Landwehrjohann, L.; Donhauser, E.; Vogt, E. T.; Stratmann, B.; Hense, J.; Luedtke, S.; Duefer, M.; Tolstik, E.; Dierks, J.; Hormann, F.-L.; Heiles, S.; Lorenz, K.; Reil, J.-C.; Schopfer, F. J.; Freeman, B. A.; Rudolph, V.; Schlomann, U.; Klinke, A.

10.1101/2024.02.20.581137 — pathology — Posted on 2024-02-22

1205 Post-transcriptional control drives Aurora kinase A expression in human cancers

Cacioppo, R.; Rad, D.; Pagani, G.; Gandellini, P.; Lindon, C.

10.1101/2024.02.22.581549 — cancer biology — Posted on 2024-02-22

1206 Common methods of making giant vesicles (except emulsion techniques) capture intended lipid ratios

Weakly, H. M. J.; Wilson, K. J.; Goetz, G. J.; Pruitt, E. L.; Li, A.; Xu, L.; Keller, S. L.

10.1101/2024.02.21.581444 — biophysics — Posted on 2024-02-22

1207 A pangenome analysis of ESKAPE bacteriophages: the underrepresentation may impact machine learning models

Lee, J.; Hunter, B.; Shim, H.

10.1101/2024.02.19.581114 — bioinformatics — Posted on 2024-02-22

1208 Soft Tissue Mechanics in Hip Distraction after Total Knee Arthroplasty: A Finite Element Analysis

Soehnlen, S. M.; Sadeqi, S.; Kumaran, Y.; Tripathi, S.; Jones, R. K.; Sohn, D. H.; Goel, V. K.

10.1101/2024.02.13.580129 — bioengineering — Posted on 2024-02-22

1209 Multi-modal Phantom Experiments, mimicking Flow through the Mitral Heart Valve

Christierson, L.; Frieberg, P.; Lala, T.; Toger, J.; Liuba, P.; Revstedt, J.; Isaksson, H.; Hakacova, N.

10.1101/2024.02.20.581131 — bioengineering — Posted on 2024-02-22

1210 The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes

Makova, K. D.; Pickett, B. D.; Harris, R. S.; Hartley, G. A.; Cechova, M.; Pal, K.; Nurk, S.; Yoo, D.; Li, Q.; Hebbar, P.; McGrath, B. C.; Antonacci, F.; Aubel, M.; Biddanda, A.; Borchers, M.; Bornberg-Bauer, E.; Bouffard, G. G.; Brooks, S. Y.; Carbone, L.; Carrel, L.; Carroll, A.; Chang, P.-C.; Chin, C.-S.; Cook, D. E.; Craig, S. J. C.; de Gennaro, L.; Diekhans, M.; Dutra, A.; Garcia, G. H.; Grady, P. G. S.; Green, R. E.; Haddad, D.; Hallast, P.; Harvey, W. T.; Hickey, G.; Hillis, D. A.; Hoyt, S. J.; Jeong, H.; Kamali, K.; Pond, S. L. K.; LaPolice, T. M.; Lee, C.; Lewis, A. P.; Loh, Y.-H. E.;

10.1101/2023.11.30.569198 — genomics — Posted on 2024-02-22

1211 Metavinculin mediates differentiation cues into myogenic gene expression.

Murugan, A.; Nanjegowda, N. B.; Jothi, M.

10.1101/2024.02.21.578728 — cell biology — Posted on 2024-02-22

1212 Fine-tuning BERT models to extract transcriptional regulatory interactions of bacteria from biomedical literature

Varela-Vega, A.; Posada-Reyes, A.-B.; Mendez-Cruz, C.-F.

10.1101/2024.02.19.581094 — molecular biology — Posted on 2024-02-22

1213 Plk3 Regulates Bacteremia and Supports Sepsis

Kostyak, J.; Sarojini, S. S.; Naik, M.; Dai, W.; Michael, J. V.; McKenzie, S.; Naik, U. P.

10.1101/2024.02.19.581105 — immunology — Posted on 2024-02-22

1214 A Neural Mechanism for Optic Flow Parsing in Macaque Visual Cortex

Peltier, N. E.; Anzai, A.; Moreno-Bote, R.; DeAngelis, G. C.

10.1101/2024.02.19.581050 — neuroscience — Posted on 2024-02-22

1215 Causal Discovery Analysis Reveals Insights into Psychosis Proneness, Brain Function, and Environmental Factors among Young Individuals

Sahin-Ilikoglu, T.; Ma, S.; Kummerfeld, E.; Rawls, E.; Tan, H. Y.; Toulopoulou, T.

10.1101/2024.02.19.581044 — neuroscience — Posted on 2024-02-22

1216 A Systematically Optimized Miniaturized Mesoscope (SOMM) for large-scale calcium imaging in freely moving mice

Zhang, Y.; Yuan, L.; Wu, J.; Noebauer, T.; Zhang, R.; Xiao, G.; Wang, M.; Xie, H.; Dai, Q.; Vaziri, A.

10.1101/2024.02.19.581043 — neuroscience — Posted on 2024-02-22

1217 Differential modulation of cortical codes for sounds of varying intensity by distinct inhibitory neurons.

Tobin, M.; Sheth, J. N.; Wood, K. C.; Michel, E. K.; Geffen, M. N.

10.1101/2023.02.01.526470 — neuroscience — Posted on 2024-02-22

1218 Intrinsic and synaptic determinants of receptive field plasticity in Purkinje cells of the mouse cerebellum

Lin, T.-F.; Busch, S. E.; Hansel, C.

10.1101/2023.07.19.549760 — neuroscience — Posted on 2024-02-22

1219 Voice patches in the marmoset auditory cortex revealed by wide-field calcium imaging

Zhang, Y.; Song, X.; Guo, Y.; Chen, C.; Osmanski, M. S.; Wang, X.

10.1101/2024.02.19.581089 — neuroscience — Posted on 2024-02-22

1220 A Telescopic Independent Component Analysis on Functional Magnetic Resonance Imaging Data Set

Mirzaeian, S.; Faghiri, A.; Calhoun, V.; Iraji, A.

10.1101/2024.02.19.581086 — neuroscience — Posted on 2024-02-22

1221 Multiparameter Quantitative Analyses of Diagnostic Cells in Brain Tissues from Tuberous Sclerosis Complex

Arceneaux, J. S.; Brockman, A.; Khurana, R.; Chalkley, M.-B. L.; Geben, L. C.; Vestal, M.; Zafar, M.; Weatherspoon, S.; Mobley, B. C.; Ess, K. C.; Ihrie, R. A.

10.1101/2024.02.19.581031 — neuroscience — Posted on 2024-02-22

1222 Evidence of sensory error threshold in triggering locomotor adaptations in humans

Herrick, E. M.; Yakovenko, S.

10.1101/2024.02.19.581021 — neuroscience — Posted on 2024-02-22

1223 Human like severe hypertriglyceridemia in a high fat fed chicken model

K, S.; JG, B.; TK, D.; Shanker, K.; R, V.; Kadiyala, G.; Saxena, U.

10.1101/2024.02.19.581080 — pharmacology and toxicology — Posted on 2024-02-22

1224 CAMKV Kinase Signaling Is a Novel Therapeutic Avenue with Prognostic Relevance in Neuroblastoma

Yu, Y.; Zhao, Y.; Shi, Z.; Cheng, F.; Wang, L. L.; Choi, J. M.; Li, K.; Silverman, D.; Qi, D.; Wang, J.; Agarwal, S.; Rood, B.; Dome, J. S.; Fabbri, M.; Yi, J. S.; Wu, E.; Jung, S. Y.; Zhang, C.; Yang, J.

10.1101/2024.02.19.581040 — cancer biology — Posted on 2024-02-22

1225 Spatiotemporal observation reveals metastatic tumor-driven vascular remodeling as a potential route to polyclonal colonization

Ikeda, Y.; Oshima, H.; Kok, S. Y.; Oshima, M.; Matsunaga, Y. T.

10.1101/2024.02.20.581134 — cancer biology — Posted on 2024-02-22

1226 Multi-gradient Permutation Survival Analysis Identifies Mitosis and Immune Signatures Steadily Associated with Cancer Patient Prognosis

Cai, X.; Ye, Y.; Liu, X.; Fang, Z.; Chen, L.; Li, F.; Ji, H.

10.1101/2024.02.20.581166 — cancer biology — Posted on 2024-02-22

1227 Antibody-drug conjugates targeting EGFR ligand Epiregulin inhibit colorectal tumor growth irrespective of RAS mutational status

Jacob, J.; Anami, Y.; High, P.; Liang, Z.; Subramanian, S.; Ghosh, S. C.; AghaAmiri, S.; Guernsey, C.; Tran, H.; Liu, Q. J.; Rowe, J. H.; Azhdarinia, A.; Tsuchikama, K.; Carmon, K. S.

10.1101/2024.02.20.581056 — cancer biology — Posted on 2024-02-22

1228 Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch

Hicks, C. W.; Rahman, S.; Gloor, S. L.; Fields, J. K.; Husby, N. L.; Vaidya, A.; Maier, K. E.; Morgan, M.; Keogh, M.-C.; Wolberger, C.

10.1101/2024.02.22.581437 — biophysics — Posted on 2024-02-22

1229 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells

Han, I.; Hua, J.; White, J. S.; O'Connor, J. T.; Nassar, L. S.; Tro, K. J.; Page-McCaw, A.; Hutson, M. S.

10.1101/2023.05.31.543122 — biophysics — Posted on 2024-02-22

1230 Machine Learning Approaches in Label-Free Small Extracellular Vesicles Analysis with Surface-Enhanced Raman Scattering (SERS) for Cancer Diagnostics

Vang, D.; Kelly, M.; Sharma, M.; Sheokand, M.; Esfandiari, L.; Dima, R. I.; Strobbia, P.

10.1101/2024.02.19.581099 — bioengineering — Posted on 2024-02-22

1231 Heritability of complex traits in sub-populations experiencing bottlenecks and growth

Taylor, C. S.; Lawson, D. J.

10.1101/2023.11.23.568467 — genetics — Posted on 2024-02-22

1232 Centriolar satellites are sites of translation of centrosomal and ciliary proteins

Pachinger, C.; Dobbelaere, J.; Rumpf-Kienzl, C.; Raina, S.; Garcia-Baucells, J.; Sarantseva, M.; Brauneis, A.; Dammermann, A.

10.1101/2024.02.22.581531 — cell biology — Posted on 2024-02-22

1233 Septin-associated PIPKIγ splice variants drive centralspindlin association with the midbody via PI(4,5)P2

Russo, G.; Hümpfer, N.; Jaensch, N.; Restel, S.; Schmied, C.; Heyd, F.; Lehmann, M.; Haucke, V.; Ewers, H.; Krauss, M.

10.1101/2024.02.22.581562 — cell biology — Posted on 2024-02-22

1234 Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

Lu, X.; Hayashi, H.; Ishikawa, E.; Takeuchi, Y.; Dychiao, J. V. T.; Nakagami, H.; Yamasaki, S.

10.1101/2023.06.06.543529 — immunology — Posted on 2024-02-22

1235 Enhanced stimulus-induced and stimulus-free gamma in open-eye meditators

Biswas, A.; Aggarwal, S.; Sharma, K.; Ray, S.

10.1101/2024.02.19.581028 — neuroscience — Posted on 2024-02-22

1236 Sniffing is initiated by the actions of dopamine on ventral striatum neurons

Johnson, N. L.; Cotelo-Larrea, A.; Stetzik, L. A.; Akkaya, U. M.; Varga, A. G.; Ma, M.; Wesson, D. W.

10.1101/2024.02.19.581052 — neuroscience — Posted on 2024-02-22

1237 Confounding factors in targeted degradation of short-lived proteins

Vetma, V.; Perez, L. C.; Elias, J.; Stingu, A.; Kombara, A.; Gmaschitz, T.; Braun, N.; Ciftci, T.; Dahmann, G.; Diers, E.; Gerstberger, T.; Greb, P.; Kidd, G.; Kofink, C.; Puoti, I.; Spiteri, V.; Trainor, N.; Westermaier, Y.; Whitworth, C.; Ciulli, A.; Farnaby, W.; McAulay, K.; Frost, A. B.; Chessum, N.; Koegl, M.

10.1101/2024.02.19.581012 — cancer biology — Posted on 2024-02-22

1238 Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis

Ippolitov, D.; Lin, Y.-H.; Spence, J.; Glogowska, A.; Thanasupawat, T.; Beiko, J.; Del Bigio, M. R.; Xu, X.; Wang, A.; Calvo, R.; Kapoor, A.; Marugan, J. J.; Henderson, M. J.; Klonisch, T.; Hombach-Klonisch, S.

10.1101/2024.02.19.581073 — cancer biology — Posted on 2024-02-22

1239 Heat Stable and Intrinsically Sterile Liquid Protein Formulations

Lawanprasert, A.; Pimcharoen, S.; Singh, H.; Vargas, M. G.; Dewan, A.; Kirimanjeswara, G. S.; Medina, S.

10.1101/2024.02.19.581015 — biophysics — Posted on 2024-02-22

1240 What shapes template matching performance in cryogenic electron tomography in situ

Maurer, V. J.; Siggel, M.; Kosinski, J.

10.1101/2023.09.06.556487 — biophysics — Posted on 2024-02-22

1241 Free radical production induced by visible light in live fruit flies

Daplan, E.; Turin, L.

10.1101/2024.02.19.580981 — biophysics — Posted on 2024-02-22

1242 A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration

Goedegebuure, M.; Bury, M.; Wang, X.; San Felice, P.; Cammarata, F.; Wang, L.; Sharma, T.; Rajinikanth, N.; Karra, V.; Siddha, V.; Sharma, A.; Ameer, G.

10.1101/2024.02.15.580554 — bioengineering — Posted on 2024-02-22

1243 Development of an Experimental Protocol to Study the Neural Control of Force and Impedance in Wrist Movements with Robotics and fMRI

Schmidt, K.; Berret, B.; Sergi, F.

10.1101/2024.02.19.581013 — bioengineering — Posted on 2024-02-22

1244 Modeling Neuromotor Adaptation to Pulsed Torque Assistance During Walking

Kim, G.; Sergi, F.

10.1101/2024.02.19.580556 — bioengineering — Posted on 2024-02-22

1245 Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

Baier, A. S.; Gioacchini, N.; Eek, P.; Leith, E. M.; Tan, S.; Peterson, C. L.

10.1101/2021.12.08.471801 — biochemistry — Posted on 2024-02-22

1246 α-catenin middle- and actin-binding domain unfolding mutants differentially impact epithelial strength and sheet migration

Quinn, J. M.; Wang, Y.; Wood, M. N.; Flozak, A. S.; Le, P. M.; Yemelyanov, A.; Oakes, P. W.; Gottardi, C. J.

10.1101/2023.02.01.526618 — cell biology — Posted on 2024-02-22

1247 The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis

Alvarez, J. A.; Gas-Pascual, E.; Malhi, S.; Njume, F. N.; Sanchez-Arcila, J. C.; van der Wel, H.; Zhao, Y.; Ceron, G.; Posada, J.; Souza, S. P.; Yap, G. S.; West, C.; Jensen, K. D. C.

10.1101/2024.02.21.581431 — microbiology — Posted on 2024-02-22

1248 What Causes Persistent Neural Activity?

Verma, V.

10.1101/2024.02.19.581018 — neuroscience — Posted on 2024-02-22

1249 Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics

Lewis-Healey, E.; Tagliazucchi, E.; Canales-Johnson, A.; Bekinschtein, T.

10.1101/2024.02.19.580985 — neuroscience — Posted on 2024-02-22

1250 Bayesian Workflow for Generative Modeling in Computational Psychiatry

Hess, A. J.; Iglesias, S.; Koechli, L.; Marino, S.; Mueller-Schrader, M.; Rigoux, L.; Mathys, C.; Harrison, O. K.; Heinzle, J.; Fraessle, S.; Stephan, K. E.

10.1101/2024.02.19.581001 — neuroscience — Posted on 2024-02-22

1251 Inhibition of Indirect Pathway Activity Causes Abnormal Decision-Making In a Mouse Model of Impulse Control Disorder in Parkinson's Disease

Zhuang, X.; Lemak, J.; Sridhar, S.; Nelson, A. B.

10.1101/2024.02.19.581062 — neuroscience — Posted on 2024-02-22

1252 Monosynaptically-interconnected Network Module (MNM) Approach for High-Resolution Brain Sub-Network Analysis

Kim, S.; Kim, Y.-E.; Ujihara, Y.; Kim, I. H.

10.1101/2024.02.19.581007 — neuroscience — Posted on 2024-02-22

1253 A Mathematical Framework for Comparison of Intermittent and Continuous Adaptive Chemotherapy Dosing in Cancer

McGehee, C.; Mori, Y.

10.1101/2024.02.19.580916 — systems biology — Posted on 2024-02-22

1254 Cryogenic non-invasive 3D X-ray phase-contrast imaging of unfixed, intact mouse joints reveals shifting chondrocyte hypertrophy across the endochondral interface

Evans, L. A.; Vezeleva, D.; Bodey, A. J.; Lee, P. D.; Poologasundarampillai, G.; Pitsillides, A. A.

10.1101/2024.02.19.580961 — physiology — Posted on 2024-02-22

1255 Risk and loss aversion and attitude to COVID and vaccines in anxious individuals

Ferrari, F.; Alexander, J.; Series, P.

10.1101/2023.05.05.539520 — pathology — Posted on 2024-02-22

1256 Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells

Ballaro, R.; Pareek, S.; Lee, J.; Patel, H.; Tirumala, P.; Liu, G.; Hayek, K.; Savage, H.; Guerrouahen, B.; Ngo-Huang, A.; Parker, N.; Katz, M. H.; Petzel, M.; McAllister, F.; Wright, R.; Tan, L.; Lorenzi, P. L.; Schadler, K.

10.1101/2024.02.14.580332 — cancer biology — Posted on 2024-02-22

1257 Structural evidence for two-stage binding of mitochondrial ferredoxin 2 to the core iron-sulfur cluster assembly complex

Steinhilper, R.; Freibert, S.-A.; Kaltwasser, S.; Lill, R.; Murphy, B. J.

10.1101/2024.02.19.580858 — biophysics — Posted on 2024-02-22

1258 Integrating population-level and cell-based signatures for drug repositioning

He, C.; Xu, Y.; Zhou, Y.; Fan, J.; Cheng, C.; Meng, R.; Gamazon, E. R.; Zhou, D.

10.1101/2023.10.25.564079 — bioinformatics — Posted on 2024-02-22

1259 Estimating Propulsion Kinetics in Absence of a Direct Measurement of the Anterior Component of Ground Reaction Force

Cohen, H. N.; Vasquez, M.; Sergi, F.

10.1101/2024.02.19.581016 — bioengineering — Posted on 2024-02-22

1260 Regional Centromere Configuration in the Fungal Pathogens of Pneumocystis Genus

Cisse, O. H.; Curran, S.; Folco, H. D.; Liu, Y.; Bishop, L.; Wang, H.; Fischer, E. R.; Davis, A. S.; Combs, C.; Dekker, J. P.; Grewal, S.; Cushion, M.; Ma, L.; Kovacs, J. A.

10.1101/2023.05.12.540427 — genomics — Posted on 2024-02-22

1261 Un1Cas12f1 and Cas9 gene drive in HSV1: Viruses that 'infect' viruses

Yao, Q.; Lin, Z.; Lai, K.; Zeng, X.; Lei, G.; Zhang, T.; Dai, H.

10.1101/2023.12.04.569968 — microbiology — Posted on 2024-02-22

1262 Energetic Demands Regulate Sleep-Wake Rhythm Circuit Development

Poe, A. R.; Zhu, L.; Tang, S. H.; Valencia, E.; Kayser, M. S.

10.1101/2023.09.19.558472 — neuroscience — Posted on 2024-02-22

1263 Lineage-tracing of Acta2+ cells in aged mice during lung fibrosis formation and resolution supports the lipofibroblasts to myofibroblast reversible switch

Lingampally, A.; Truchi, M.; Mauduit, O.; Delcroix, V.; Hadzic, S.; Koepke, J.; Vazquez-Armendariz, A.-I.; Herold, S.; Samakovlis, C.; Makarenkova, H.; El Agha, E.; Chen, C.; Mari, B.; Bellusci, S.

10.1101/2024.02.19.580952 — pathology — Posted on 2024-02-22

1264 Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction

Latini, S.; Venafra, V.; Massacci, G.; Bica, V.; Graziosi, S.; Pugliese, G. M.; Iannuccelli, M.; Frioni, F.; Minnella, G.; Marra, J. D.; Chiusolo, P.; Pepe, G.; Helmer-Citterich, M.; Mougiakakos, D.; Boettcher, M.; Fischer, T.; Perfetto, L.; Sacco, F.

10.1101/2023.06.22.546072 — cancer biology — Posted on 2024-02-22

1265 Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

Alexander, A. K.; Rodriguez, K. F.; Chen, Y.-Y.; Amato, C.; Estermann, M. A.; Xu, X.; Yao, H.

10.1101/2024.02.19.581036 — developmental biology — Posted on 2024-02-22

1266 Regulatory interactions between daptomycin and bacitracin responsive pathways coordinate the cell envelope antibiotic resistance response of Enterococcus faecalis

Morris, S. M.; Wiens, L.; Rose, O.; Fritz, G.; Rogers, T.; Gebhard, S.

10.1101/2022.11.16.516778 — microbiology — Posted on 2024-02-22

1267 Generalizable Neural Models of Emotional Engagement and Disengagement

Nanni Zepeda, M.; Evans, T.; Jagger-Rickels, A.; Raz, G.; Hendler, T.; Fan, Y.; Grimm, S.; Walter, M.; Esterman, M.; Zuberer, A.

10.1101/2024.02.15.579332 — neuroscience — Posted on 2024-02-22

1268 Diaminopurine in Nonenzymatic RNA Template Copying

Jia, X.; Fang, Z.; Kim, S. C.; Ding, D.; Zhou, L.; Szostak, J. W.

10.1101/2024.02.20.581310 — biochemistry — Posted on 2024-02-22

1269 Predicting cell type-specific epigenomic profiles accounting for distal genetic effects

Murphy, A. E.; Beardall, W.; Rei, M.; Phuycharoen, M.; Skene, N. G.

10.1101/2024.02.15.580484 — genomics — Posted on 2024-02-22

1270 The evolution of 5'UTR length was shaped by natural selection for its functional impact on gene expression

Zhan, Y.; Hu, Z.; Lu, Z.; Lin, Z.

10.1101/2024.02.17.580833 — genomics — Posted on 2024-02-22

1271 UPP affects chloroplast development by interfering with chloroplast proteostasis

Scherer, V.; Bellin, L.; Schwenkert, S.; Lehmann, M.; Rinne, J.; Witte, C.-P.; Jahnke, K.; Richter, A. S.; Pruss, T.; Lau, A. S.; Waller, L.; Stein, S.; Leister, D.; Moehlmann, T.

10.1101/2023.08.28.555145 — molecular biology — Posted on 2024-02-22

1272 Exposure assessment suggests some cytotoxic Bacillus cereus group genotypes can grow over 3 logs in HTST milk throughout the shelf life at temperature abuse conditions

Su, J.; Chandross-Cohen, T.; Qian, C.; Carroll, L. M.; Kimble, K.; Yount, M.; Wiedmann, M.; Kovac, J.

10.1101/2024.02.20.581219 — microbiology — Posted on 2024-02-22

1273 Convergent evolution of plant prickles is drivenby repeated gene co-option over deep time

Satterlee, J. W.; Alonso, D.; Gramazio, P.; Jenike, K. M.; He, J.; Arrones, A.; Villanueva, G.; Plazas, M.; Ramakrishnan, S.; Benoit, M.; Gentile, I.; Hendelman, A.; Shohat, H.; Fitzgerald, B.; Robitaille, G. M.; Green, Y.; Swartwood, K.; Passalacqua, M. J.; Gagnon, E.; Hilgenhof, R.; Huggins, T. D.; Eizenga, G. C.; Gur, A.; Rutten, T.; Stein, N.; Yao, S.; Bellot, C.; Bendahmane, M.; Frary, A.; Knapp, S.; Sarkinen, T.; Gillis, J.; Van Eck, J.; Schatz, M. C.; Eshed, Y.; Prohens, J.; Vilanova, S.; Lippman, Z. B.

10.1101/2024.02.21.581474 — evolutionary biology — Posted on 2024-02-22

1274 Generation of diversity in the blue cheese mold Penicillium roqueforti and identification of pleiotropic QTL for key cheese-making phenotypes

Caron, T.; Crequer, E.; Le Piver, M.; Le Prieur, S.; Sammy, B.; Snirc, A.; Cueff, G.; Roueyre, D.; Place, M.; Chassard, C.; Simon, A.; Rodriguez de la Vega, R. C.; Coton, M.; Coton, E.; Foulongne-Oriol, M.; Branca, A.; Giraud, T.

10.1101/2024.02.22.581506 — evolutionary biology — Posted on 2024-02-22

1275 The 2023 wildfire season in Quebec: an overview of extreme conditions, impacts, lessons learned and considerations for the future.

Boulanger, Y.; Arseneault, D.; Belisle, A.-C.; Bergeron, Y.; Boucher, J.; Boucher, Y.; Danneyrolles, V.; Erni, S.; Gachon, P.; Girardin, M.; Grant, E.; Grondin, P.; Jette, J.-P.; Labadie, G.; Leblond, M.; Leduc, A.; Puigdevall, J. P.; St-Laurent, M.-H.; Tremblay, J.; Waldron, K.

10.1101/2024.02.20.581257 — ecology — Posted on 2024-02-22

1276 De Novo Sensorimotor Skill Learning Through Reuse of Movement Components

Gabriel, G. A.; Mushtaq, F.; Morehead, J. R.

10.1101/2024.02.20.581156 — neuroscience — Posted on 2024-02-22

1277 ABCA1 deficiency causes tissue-specific dysregulation of the SREBP2 pathway in mice

Yamauchi, Y.; Abe-Dohmae, S.; Iwamoto, N.; Sato, R.; Yokoyama, S.

10.1101/2024.02.20.580966 — physiology — Posted on 2024-02-22

1278 Macropinocytosis mediates resistance to loss of glutamine transport in triple-negative breast cancer

Wahi, K.; Freidman, N.; Wang, Q.; Devadason, M.; Quek, L.-E.; Pang, A.; Lloyd, L.; Larance, M.; Zanini, F.; Harvey, K.; O'Toole, S.; Guan, Y. F.; Holst, J.

10.1101/2024.02.21.581493 — cancer biology — Posted on 2024-02-22

1279 Emerin deficiency drives MCF7 cells to an invasive phenotype

Hansen, E.; Holaska, J. M.; Rolling, C.; Wang, M.

10.1101/2024.02.21.581379 — cancer biology — Posted on 2024-02-22

1280 Lipid membrane topographies are regulators for the spatial distribution of liquid protein condensates

Kang, C. Y.; Chang, Y.; Zieske, K.

10.1101/2024.02.20.580889 — biophysics — Posted on 2024-02-22

1281 Impact of Triplet State Population on GFP-type Fluorescence and Photobleaching

Byrdin, M.; Byrdina, S.

10.1101/2024.02.19.580967 — biophysics — Posted on 2024-02-22

1282 Genetic Stability of Mycobacterium smegmatis under the Stress of First-Line Antitubercular Agents: Assessing Mutagenic Potential

Molnar, D.; Suranyi, E. V.; Trombitas, T.; Füzesi, D.; Hirmondo, R.; Toth, J.

10.1101/2024.02.21.581394 — molecular biology — Posted on 2024-02-22

1283 Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

Wen, Z.; Li, P.; Yuan, Y.; Wang, C.; Li, M.; Wang, H.; Shi, M.; He, Y.; Cui, M.; Chen, L.; Sun, C.

10.1101/2024.02.20.581122 — microbiology — Posted on 2024-02-22

1284 Contribution of Urea to Nitrite Production in Southern Ocean Waters with Contrasting Nitrifying Communities

Hollibaugh, J. T.; Okotie-Oyekan, A.; Damashek, J.; Ducklow, H.; Popp, B.; Wallsgrove, N.; Allen, T.

10.1101/2024.02.20.581251 — microbiology — Posted on 2024-02-22

1285 The GPI sidechain of Toxoplasma gondii prevents parasite pathogenesis

Alvarez, J. A.; Gas-Pascual, E.; Malhi, S.; Njume, F. N.; Sanchez-Arcila, J. C.; van der Wel, H.; Zhao, Y.; Ceron, G.; Posada, J.; Souza, S. P.; Yap, G. S.; West, C.; Jensen, K. D. C.

10.1101/2024.02.21.581431 — microbiology — Posted on 2024-02-22

1286 Maturing neutrophils of lower density associate with thrombocytopenia in Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome

Cabrera, L. E.; Tietavainen, J.; Jokiranta, S. T.; Makela, S. M.; Vaheri, A.; Mustonen, J.; Vapalahti, O.; Kanerva, M.; Strandin, T.

10.1101/2024.02.19.580937 — immunology — Posted on 2024-02-22

1287 Comparative analyses of adsorbed circulating proteins in the PMMA and PES hemodiafilters in patients on predilution online hemodiafiltration

Islam, M. S.; Ema, S.; Nabi, M. M.; Rahman, M. M.; Waliullah, A. S. M.; Yan, J.; Ferdous, R.; Sakamoto, T.; Takahashi, Y.; Kato, A.; Kahyo, T.; Sato, T.; Setou, M.

10.1101/2024.02.16.580786 — pathology — Posted on 2024-02-22

1288 Impact of Triplet State Population on GFP-type Fluorescence and Photobleaching

Byrdin, M.; Byrdina, S.

10.1101/2024.02.19.580967 — biophysics — Posted on 2024-02-22

1289 Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever

Gravett, M. S. C.; Klebl, D. P.; Harlen, O. G.; Read, D. J.; Harris, S. A.; Muench, S. P.; Peckham, M.

10.1101/2023.03.19.533260 — biophysics — Posted on 2024-02-22

1290 Interactive visualisation of raw nanopore signal data with Squigualiser

Samarakoon, H.; Liyanage, K.; Ferguson, J.; Parameswaran, S.; Gamaarachchi, H.; Deveson, I.

10.1101/2024.02.19.581111 — bioinformatics — Posted on 2024-02-22

1291 Pre-mRNA fate decision safeguards the fidelity of the inflammatory response

Bestehorn, A. M.; Fesselet, J. A. M.; Didusch, S.; Zeiler, C.; Doppelmayer, K.; Borroni, M.; Le Heron, A.; Pfanzagl, V.; Chen, W.; Scinicariello, S.; Baccarini, M.; Versteeg, G. A.; Hartl, M.; Kovarik, P.

10.1101/2023.11.30.569392 — molecular biology — Posted on 2024-02-22

1292 Streptococcus pneumoniae augments circadian clock gene expression in zebrafish cells

Morales Fenero, C.; Sacksteder, R. E.; Kimmey, J. M.

10.1101/2024.02.20.581283 — microbiology — Posted on 2024-02-22

1293 Beyond the Colony-Forming-Unit: Rapid Bacterial Evaluation in Osteomyelitis

Sun, Q.; Huynh, K.; Muratovic, D.; Gunn, N. J.; Zelmer, A. R.; Solomon, L. B.; Atkins, G. J.; Yang, D.

10.1101/2023.11.21.568051 — microbiology — Posted on 2024-02-22

1294 Discovery and Repurposing of Pharmaceutical Agents as Antifungals: In vivo activity against Coccidioides

Mead, H.; Valentine, M.; Thompson, G. R.; Yin, H.; Keim, P.; Engelthaler, D. M.; Barker, B. M.

10.1101/2024.02.21.581462 — microbiology — Posted on 2024-02-22

1295 Myelin dystrophy in the aging prefrontal cortex leads to impaired signal transmission and working memory decline: a multiscale computational study

Ibanez, S.; Sengupta, N.; Luebke, J.; Wimmer, K.; Weaver, C. M.

10.1101/2023.08.30.555476 — neuroscience — Posted on 2024-02-22

1296 How the Anatomy of the Epidermal Cells Is Correlated to the Transient Response of Stomata

Zekri, M. A.; Tholen, D.; Koller, L.; Lang, I.; Theroux-Rancourt, G.

10.1101/2024.02.15.580521 — physiology — Posted on 2024-02-22

1297 The Architecture of Sponge Choanocyte Chambers Maximizes Mechanical Pumping Efficiency

Ogawa, T.; Koyama, S.; Omori, T.; Kikuchi, K.; de Maleprade, H.; Goldstein, R. E.; Ishikawa, T.

10.1101/2024.02.22.581376 — biophysics — Posted on 2024-02-22

1298 Effects of time-dependent ATP consumption caused by neuron firing on ATP concentrations in synaptic boutons containing and lacking a stationary mitochondrion

Kuznetsov, A. V.

10.1101/2024.02.20.581271 — biophysics — Posted on 2024-02-22

1299 The CryoEM structure of human serum albumin in complex with ligands

Catalano, C.; Lucier, K. W.; To, D.; Senko, S.; Tran, N. L.; Farwell, A. C.; Silva, S. M.; Dip, P. V.; Poweleit, N.; Scapin, G.

10.1101/2024.02.21.581427 — biochemistry — Posted on 2024-02-22

1300 An Engineered IGF2 Mutant for Lysosomal Targeting Chimeras Development and Membrane Proteins Degradation

Pan, Y.; Xiang, Q.; Deng, K.; Anwar, M.; Wang, L.; Wang, Y.; Liang, Q.; Shen, L.; Yang, J.; Shen, W.

10.1101/2024.02.20.581320 — biochemistry — Posted on 2024-02-22

1301 Quantitative genetics of natural S. cerevisiae strains upon sexual mating reveals heritable determinants of cellular fitness

Struass, S. K.; Golomb, R.; Sheykhkarimli, D.; Liti, G.; Dahan, O.; Pilpel, Y. T.

10.1101/2024.02.12.579867 — genetics — Posted on 2024-02-22

1302 Augmentation of DNA exonuclease TREX1 in macrophages as a therapy for cardiac ischemic injury

Ibrahim, A. G.-E.; Ciullo, A.; Miyamoto, K.; Liao, K.; Jones, X.; Yamaguchi, S.; Li, C.; Rannou, A.; Nawaz, A.; Morris, A. A.; Tsi, K.; Marban, C. H.; Lee, J.; Manriquez, N.; Hong, Y.; Kumar, A. N.; Dawkins, J. F.; Rogers, R. G.; Marban, E.

10.1101/2024.02.20.581294 — molecular biology — Posted on 2024-02-22

1303 A modular toolkit for environmental Rhodococcus, Gordonia, and Nocardia enables complex metabolic manipulation.

Jansen, Z.; Alameri, A.; Wei, Q.; Kulhanek, D. L.; Gilmour, A. R.; Halper, S.; Schwalm, N. D.; Thyer, R.

10.1101/2024.02.21.581484 — microbiology — Posted on 2024-02-22

1304 DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders

Lim, M.; Do Cong, T.; Orr, L. M.; Toriki, E. S.; Kile, A. C.; Papatzimas, J. W.; Lee, E.; Nomura, D. K.

10.1101/2024.02.20.580683 — biochemistry — Posted on 2024-02-22

1305 Diaminopurine in Nonenzymatic RNA Template Copying

Jia, X.; Fang, Z.; Kim, S. C.; Ding, D.; Zhou, L.; Szostak, J. W.

10.1101/2024.02.20.581310 — biochemistry — Posted on 2024-02-22

1306 Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus

Fernandez, I.; Saunders, N.; Duquerroy, S.; Bolland, W. H.; Arbabian, A.; Baquero, E.; Blanc, C.; Lafaye, P.; Haouz, A.; Buchrieser, J.; Schwartz, O.; Rey, F. A.

10.1101/2024.02.21.581378 — biochemistry — Posted on 2024-02-22

1307 Senataxin modulates resistance to cisplatin through an R-loop mediated mechanism in HPV-associated Head and Neck Squamous Cell Carcinoma

Crane, H.; Carr, I.; Hunter, K.; El-Khamisy, S. F.

10.1101/2024.02.22.581374 — molecular biology — Posted on 2024-02-22

1308 Thermostable in vitro transcription-translation for enzyme screening in microdroplets

Ribeiro, A.-L.; Perez-Arnaiz, P.; Sanchez-Costa, M.; Perez, L.; Almendros, M.; van Vliet, L.; Gielen, F.; Lim, J.; Charnock, S.; Hollfelder, F.; Gonzalez-Pastor, J. E.; Berenguer, J.; Hidalgo, A.

10.1101/2024.02.22.580490 — microbiology — Posted on 2024-02-22

1309 Rapid generation and screening of transgenic black soldier fly (Hermetia illucens)

Pfitzner, C.; Tepper, K.; Kumar, S.; Retief, C.; McNab, J.; Harrell, R. A.; Maselko, M.

10.1101/2024.02.21.581498 — synthetic biology — Posted on 2024-02-22

1310 Elimination of subtelomeric repeat sequences exerts little effect on telomere essential functions in Saccharomyces cerevisiae

Hu, C.; Zhu, X.; He, M.-H.; Shao, Y.; Qin, Z.; Wu, Z.; Zhou, J.

10.1101/2023.08.29.555450 — genetics — Posted on 2024-02-22

1311 Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation

Shinoda, S.; Sakai, Y.; Matsui, T.; Uematsu, M.; Koyama-Honda, I.; Sakamaki, J.-i.; Yamamoto, H.; Mizushima, N.

10.1101/2023.09.11.557142 — cell biology — Posted on 2024-02-22

1312 Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

Lazzarin, E.; Gradisch, R.; Skopec, S. M.; Alves da Silva, L.; Sebastianelli-Schoditsch, C.; Szollosi, D.; Maier, J.; Sucic, S.; Roblek, M.; Kanner, B.; Sitte, H. H.; Stockner, T.

10.1101/2023.10.10.561652 — molecular biology — Posted on 2024-02-22

1313 Targeting CD19 for the treatment of B-cell related autoimmune diseases with a novel T cell engager

Yuan, A. Q.; Yuan, R. Q.; zhao, L.; Yang, I.; Bai, L.; Meng, Q.

10.1101/2024.02.17.580750 — immunology — Posted on 2024-02-22

1314 Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis

Wei, J.; Moon, J.; Yasumizu, Y.; Zhang, L.; Radassi, K.; Buitrago-Pocasangre, N.; Deerhake, M. E.; Strauli, N.; Chan, A.; Herman, A.; Pedotti, R.; Raposo, C.; Yim, I.; Pappalardo, J.; Longbrake, E. E.; Sumida, T. S.; Axisa, P.-P.; Hafler, D. A.

10.1101/2024.02.07.576204 — immunology — Posted on 2024-02-22

1315 Manipulating syntax without taxing working memory: MEG correlates of syntactic dependencies in a Verb-Second language

Krogh, S.; Pylkkanen, L.

10.1101/2024.02.20.581245 — neuroscience — Posted on 2024-02-22

1316 Exposure to bilingual or monolingual maternal speech during pregnancy affects the neurophysiological encoding of speech sounds in neonates differently

Arenillas-Alcon, S.; Gorina-Careta, N.; Puertollano, M.; Mondejar-Segovia, A.; Ijjou-Kadiri, S.; Costa-Faidella, J.; Gomez-Roig, M. D.; Escera, C.

10.1101/2024.02.21.579933 — neuroscience — Posted on 2024-02-22

1317 Behavioral fingerprinting of the naked mole-rat uncovers signatures of eusociality and social touch

Schwark, R.; Ogundare, S.; Weinreb, C.; Sheng, P.; Foster, W.; Toussaint, A.; Chang, P.; Tsai, Y.-Y.; Comfere, M.; Arnold, A.; Guadagnino, A.; McCloskey, D.; Schaffer, E.; Rajan, K.; Datta, S. R.; Abdus-Saboor, I.

10.1101/2024.02.21.581483 — neuroscience — Posted on 2024-02-22

1318 Female mice lacking GluA3 show early onset of hearing loss, synaptopathy, and afferent swellings in ambient sound levels

Pal, I.; Bhattacharyya, A.; V-Ghaffari, B.; Williams, E. D.; Xiao, M.; Rutherford, M. A.; Rubio, M. E.

10.1101/2024.02.21.581467 — neuroscience — Posted on 2024-02-22

1319 Fetal brain response to maternal inflammation requires microglia

Ostrem, B.; Dominguez Iturza, N.; Stogsdill, J.; Faits, T.; Kim, K.; Levin, J. Z.; Arlotta, P.

10.1101/2024.02.21.581282 — neuroscience — Posted on 2024-02-22

1320 Incomplete remyelination via endogenous or therapeutically enhanced oligodendrogenesis is sufficient to recover visual cortical function

Nunes, G. D.-F.; Osso, L. A.; Haynes, J. A.; Morris, A. M.; Conant, L.; Stockton, M. E.; Thornton, M. A.; Vivian, J. A.; Gandhi, R.; Denman, D. J.; Hughes, E. G.

10.1101/2024.02.21.581491 — neuroscience — Posted on 2024-02-22

1321 Unveiling Inter-Embryo Variability in Spindle Length over time: towards Quantitative Phenotype Analysis.

Le Cunff, Y.; Chesneau, L.; Pastezeur, S.; Pinson, X.; Soler, N.; Fairbrass, D.; Mercat, B.; Rodriguez Garcia, R.; Alayan, Z.; Abdouni, A.; de Neidhardt, G.; Costes, V.; Anjubault, M.; Bouvrais, H.; Heligon, C.; Pecreaux, J.

10.1101/2023.05.01.538870 — bioinformatics — Posted on 2024-02-21

1322 Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations

Lewis, M. A.; Lachgar-Ruiz, M.; Di Domenico, F.; Duddy, G.; Chen, J.; Fernandez, S.; Morin, M.; Williams, G.; Moreno-Pelayo, M. A.; Steel, K. P.

10.1101/2024.02.20.581141 — genetics — Posted on 2024-02-21

1323 The modification landscape of P. aeruginosa tRNAs

Mandler, M. D.; Maligireddy, S. S.; Guinlet, W. M.; Fitzsimmons, C. M.; McDonald, K. S.; Warrel, D. L.; Batista, P. J.

10.1101/2024.02.21.581370 — microbiology — Posted on 2024-02-21

1324 Adaptations of microbial genomes to human body chemistry

Dick, J. M.

10.1101/2023.02.12.528246 — microbiology — Posted on 2024-02-21

1325 Cone-opponent ganglion cells in the primate fovea tuned to non-cardinal color directions

Godat, T.; Kohout, K.; Parkins, K.; Yang, Q.; McGregor, J. E.; Merigan, W. H.; Williams, D. R.; Patterson, S. S.

10.1101/2023.09.15.557995 — neuroscience — Posted on 2024-02-21

1326 Adult-born granule cells modulate CA2 network activity during retrieval of developmental memories of the mother

Laham, B. J.; Gore, I. R.; Brown, C. J.; Gould, E.

10.1101/2023.06.14.545015 — neuroscience — Posted on 2024-02-21

1327 Motor adaptation to environment changes predicting interactable object behaviour can be flexible and implicit

Modchalingam, S.; King, A.; 't Hart, B. M.; Henriques, D. Y. P.

10.1101/2024.02.06.579172 — neuroscience — Posted on 2024-02-21

1328 Host 5-HT affects Plasmodium transmission in mosquitoes via modulating mosquito mitochondrial homeostasis

Gao, L.; Zhang, B.; Feng, Y.; Yang, W.; Zhang, S.; Wang, J.

10.1101/2024.02.19.580972 — pathology — Posted on 2024-02-21

1329 YAP promotes chromosomal instability by transcriptionally activating AJUBA through its super enhancer in breast cancer

Huang, Q.; Zhang, R.; Meng, W.; Dong, H.; Qi, Z.; Chen, Z.; Liu, L.; Shen, J.; Xie, D.

10.1101/2024.02.19.579918 — cancer biology — Posted on 2024-02-21

1330 Proteomic Insights into Breast Cancer Response to Brain Cell-Secreted Factors

Ahuja, S.; Lazar, I. M.

10.1101/2023.10.22.563488 — cancer biology — Posted on 2024-02-21

1331 Allelic DNA synthesis followed by template switching underlies BRCA1-linked tandem duplication

Huang, Z.-C.; Feng, Y.-L.; Liu, Q.; Chen, R.-D.; Liu, S.-C.; Wang, M.; Xie, A.-Y.

10.1101/2024.02.20.581123 — cancer biology — Posted on 2024-02-21

1332 Long-term dynamics of adaptation to a warming environment is dependent on historical background

Antunes, M. A.; Grandela, A.; Matos, M.; Simoes, P.

10.1101/2024.02.15.580572 — evolutionary biology — Posted on 2024-02-21

1333 Resolving Paradoxes in Molecular Evolution: The Integrated WF-Haldane (WFH) Model of Genetic Drift

Ruan, Y.; Wang, X.; Hou, M.; Diao, W.; Xu, S.; Wen, H.; Wu, C.-I.

10.1101/2024.02.19.581083 — evolutionary biology — Posted on 2024-02-21

1334 Membrane contact sites regulate vacuolar fission via sphingolipid metabolism

Hanaoka, K.; Nishikawa, K.; Ikeda, A.; Schlarmann, P.; Sasaki, S.; Yamashita, S.; Nakaji, A.; Fujii, S.; Funato, K.

10.1101/2023.06.21.546015 — cell biology — Posted on 2024-02-21

1335 Habit learning shapes activity dynamics in the central nucleus of the amygdala

Amaya, K. A.; Carmichael, J. E.; Townsend, E. S.; Palmer, J. A.; Stott, J. J.; Smith, K. S.

10.1101/2024.02.20.580730 — neuroscience — Posted on 2024-02-21

1336 Cas9 nickase-mediated contraction of CAG/CTG repeatsat multiple disease loci

Murillo, A.; Alpaugh, M.; Larin, M.; Randall, E. L.; Heraty, L.; Durairaj, R. R.; Aston, A. N.; Taylor, A. S.; Monteys, A. M.; Stoberl, N.; Heuchan, A. E.; Aeschlimann, P.; Bhattacharyya, S.; Allen, N. D.; Puymirat, J.; Davidson, B. L.; Chicchetti, F.; Lelos, M.; Dion, V.

10.1101/2024.02.19.580669 — neuroscience — Posted on 2024-02-21

1337 FECDO-Flexible and Efficient Coding for DNA Odyssey

Sun, F.; Qian, L.

10.1101/2024.02.18.580107 — bioinformatics — Posted on 2024-02-21

1338 Strain-specific evolution and host-specific regulation of transposable elements in the model plant symbiont Rhizophagus irregularis

Oliveira, J. I. N.; Corradi, N.

10.1101/2023.12.01.569630 — genomics — Posted on 2024-02-21

1339 The homie insulator has sub-elements with different insulating and long-range pairing properties

Fujioka, M.; Ke, W.; Schedl, P.; Jaynes, J. B.

10.1101/2024.02.01.578481 — genetics — Posted on 2024-02-21

1340 Tertiary lymphoid structure-related immune infiltrates in NSCLC tumor lesions correlate with low tumor-reactivity of TIL products

Castenmiller, S. M.; Kanagasabesan, N.; Guislain, A.; Nicolet, B.; van Loenen, M.; Monkhorst, K.; Veenhof, A.; Smit, E.; Hartemink, K.; Haanen, J.; de Groot, R.; Wolkers, M.

10.1101/2024.02.19.580998 — immunology — Posted on 2024-02-21

1341 Prior cocaine use diminishes encoding of latent information by orbitofrontal, but not medial, prefrontal ensembles

Mueller, L.; Konya, C.; Sharpe, M.; Wikenheiser, A. M.; Schoenbaum, G.

10.1101/2024.02.21.581248 — neuroscience — Posted on 2024-02-21

1342 Drosophila epidermal cells are intrinsically mechanosensitive and modulate nociceptive behavioral outputs

Yoshino, J.; Mali, S.; Williams, C.; Morita, T.; Emerson, C.; Arp, C.; Miller, S.; Yin, C.; The, L.; Chikaya, H.; Motoyoshi, M.; Ishii, K.; Emoto, K.; Bautista, D. M.; Parrish, J. Z.

10.1101/2022.10.07.511265 — neuroscience — Posted on 2024-02-21

1343 Massive Multiplexing of Spatially Resolved Single Neuron Projections with Axonal BARseq

Yuan, L.; Chen, X.; Zhan, H.; Gilbert, H. L.; Zador, A. M.

10.1101/2023.02.18.528865 — neuroscience — Posted on 2024-02-21

1344 Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors

Meisner, O. C.; Fagan, N. A.; Greenwood, J.; Shi, W.; Jadi, M.; Nandy, A. S.; Chang, S. W. C.

10.1101/2024.02.16.579531 — neuroscience — Posted on 2024-02-21

1345 Plastic vasomotion entrainment

Sasaki, D.; Imai, K.; Ikoma, Y.; Matsui, K.

10.1101/2023.11.20.567853 — neuroscience — Posted on 2024-02-21

1346 Prevalence and genotypes of Chlamydia psittaci in pet birds of Hong Kong

Ko, J. C. K.; Choi, Y. W. Y.; Poon, E. S. K.; Wyre, N.; Go, J. L. L.; Poon, L. L. M.; Sin, S. Y. W.

10.1101/2024.02.19.581005 — zoology — Posted on 2024-02-21

1347 Antimicrobial resistance, virulence genes profiles and molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae strains from captive giant pandas (Ailuropoda melanoleuca)

YAN, X.; Yang, M.; Edward Ayala, J.; Li, L.; Zhou, Y.; Hou, R.; Liu, S.; Li, Y.; Yue, C.; Zhang, D.; Su, X.

10.1101/2024.02.20.581254 — zoology — Posted on 2024-02-21

1348 Endothelial cells signaling and patterning under hypoxia: a mechanistic integrative computational model including the Notch-Dll4 pathway

Oliveira, R. H. d. M.; Annex, B. H.; Popel, A. S.

10.1101/2023.05.03.539270 — systems biology — Posted on 2024-02-21

1349 Nodulation Trio in Medicago truncatula: Unveiling the Overlapping Roles of MtLYK2, MtLYK3, and MtLYK2bis

Li, Y.; Zhao, Y.; Yan, Z.; Dong, R.; Yu, H.; Zhu, H.; Cao, Y.

10.1101/2024.02.19.577609 — plant biology — Posted on 2024-02-21

1350 FLOWERING LOCUS C integrates carbon and nitrogen signaling for the proper timing of flowering in Arabidopsis

Gramma, V.; Olas, J. J.; Zacharaki, V.; Ponnu, J.; Luzarowska, U.; Musialak-Lange, M.; Wahl, V.

10.1101/2024.02.15.580522 — plant biology — Posted on 2024-02-21

1351 The DC1 domain protein Vacuoleless Gametophytes regulates stamen development in Arabidopsis

Amigo, N. L.; Arias, L. A.; Marchetti, M. F.; D'Ippolito, S.; Frik, J.; Lombardo, M. C.; Terrile, M. C.; Casalongue, C. A.; Pagnussat, G. C.; Fiol, D. F.

10.1101/2024.02.19.580957 — plant biology — Posted on 2024-02-21

1352 A circadian transcriptional sub-network and EARLY FLOWERING 3 control timing of senescence and grain nutrition in bread wheat

Buckley, C. R.; Boyte, J. M.; Albiston, R. L.; Hyles, J.; Beasley, J. T.; Johnson, A. A.; Trevaskis, B.; Fournier-Level, A.; Haydon, M. J.

10.1101/2024.02.19.580927 — plant biology — Posted on 2024-02-21

1353 Elucidating molecular responses to spittlebug attack in Paspalum regnellii

Begnami, I. S.; Aono, A. H.; Graciano, D. S.; Carmello-Guerreiro, S. M.; Ferreira, R. C. U.; Malago, W.; Gusmao, M. R.; Souza, A. P.; Vigna, B. B. Z.

10.1101/2023.08.29.555367 — plant biology — Posted on 2024-02-21

1354 Sucrose-responsive osmoregulation of plant cell size by a long non-coding RNA

Hajny, J.; Travnickova, T.; Rony, R. M. I. K.; Sacharowski, S.; Krzyszton, M.; Zalabak, D.; Hardtke, C.; Pecinka, A.; Swiezewski, S.; Van Norman, J. M.; Novak, O.

10.1101/2024.02.19.581113 — plant biology — Posted on 2024-02-21

1355 Effect of the SAS chromatin-remodeling complex on chromatin accessibility during flower development

Guo, J.; Liu, Z.-Z.; Su, Y.-N.; He, X.-J.

10.1101/2024.02.20.581124 — plant biology — Posted on 2024-02-21

1356 Interlimb coordination in Parkinson's disease is minimally affected by a visuospatial dual task

Hill, A.; Nantel, J.

10.1101/2022.07.15.500215 — pathology — Posted on 2024-02-21

1357 Genetic diversity in vector populations influences the transmission efficiency of an important plant virus

Leybourne, D. J.; Whitehead, M. A.; Will, T.

10.1101/2024.02.21.581289 — pathology — Posted on 2024-02-21

1358 Development of an orthotopic medulloblastoma zebrafish model for rapid drug testing.

van Bree, N. F. H. N.; Oppelt, A.-S.; Lindstrom, S.; Zhou, L.; Boutin, L.; Johnsen, J. I.; Brautigam, L.; Wilhelm, M. T.

10.1101/2024.02.21.578208 — cancer biology — Posted on 2024-02-21

1359 The SUMOylation inhibitor TAK-981 (Subasumstat) triggers IFN-I-dependent activation of Natural Killer cells against Acute Myeloid Leukemias.

Hallal, R.; De Toledo, M.; Tempe, D.; Zemiti, S.; Coenon, L.; Gitenay, D.; George, S.; Bonnet, S.; Gabellier, L.; Cartron, G.; Pelegrin, M.; Villalba, M.; Bossis, G.

10.1101/2024.02.19.580882 — cancer biology — Posted on 2024-02-21

1360 Epigenetic histone modifications H3K36me3 and H4K5/8/12/16ac induce open polynucleosome conformations via different mechanisms

Lin, Y.-Y.; Muller, P.; Karagianni, E.; Vanderlinden, W.; Lipfert, J.

10.1101/2024.02.19.580980 — biophysics — Posted on 2024-02-21

1361 Length-dependent Intramolecular Coil-to-Globule Transition in Poly(ADP-ribose) Induced by Cations

Wang, T.; Coshic, K.; Badiee, M.; Aksimentiev, A.; Pollack, L.; Leung, A.

10.1101/2023.10.25.564012 — biophysics — Posted on 2024-02-21

1362 Personalized composite scaffolds for accelerated cell- and growth factor-free craniofacial bone regeneration

Kim, M.; Collins, C.; Liu, Y.; Tsal, H.-M.; Ahn, Y.; Wang, X.; Song, J.; Duan, C.; Sun, C.; Yi, Z.; He, T.-C.; Reid, R.; Ameer, G.

10.1101/2024.02.18.580898 — bioengineering — Posted on 2024-02-21

1363 Random walks with spatial and temporal resets may underlie searching movements in ants

Lecheval, V.; Robinson, E. J. H.; Mann, R. P.

10.1101/2024.02.20.581181 — animal behavior and cognition — Posted on 2024-02-21

1364 The genomic and cultural diversity of the Inka Qhapaq hucha ceremony in Chile and Argentina

Castro, C. d. l. F.; Cortes, C.; Raghavan, M.; Castillo, D.; Castro, M.; Verdugo, R.; Moraga, M.

10.1101/2024.02.19.581063 — genomics — Posted on 2024-02-21

1365 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems

Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Mckeown, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M.

10.1101/2024.02.19.579948 — genomics — Posted on 2024-02-21

1366 Single-cell multimodal profiling of monocytes reveals diverse phenotypes and alterations linked to cardiovascular disease risks

Bashore, A. C.; Xue, C.; Kim, E.; Yan, H.; Zhu, L. Y.; Kissner, M.; Ross, L.; Zhang, H.; Li, M.; Reilly, M.; Pan, H.

10.1101/2024.02.18.580913 — genomics — Posted on 2024-02-21

1367 Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses

Cooper, D. G.; Cowden, J. P.; Stanley, P. A.; Karbowski, J. T.; Gaertig, V. S.; Lukan, C. J.; Vo, P. M.; Worthington, A. D.; Class, C. A.

10.1101/2024.02.19.581045 — genomics — Posted on 2024-02-21

1368 Genetic Modulation of Protein Expression in Rat Brain

Li, L.; Wu, Z.; Guarracino, A.; Villani, F.; Kong, D.; Mancieri, A.; Zhang, A.; Saba, L. M.; Chen, H.; Brozka, H.; Vales, K.; Senko, A. N.; Kempermann, G.; Stuchlik, A.; Pravenec, M.; Prins, P.; Peng, J.; Williams, R.; Wang, X.

10.1101/2024.02.17.580840 — genetics — Posted on 2024-02-21

1369 Cephalopod Sex Determination and its AncientEvolutionary Origin Revealed by Chromosome-levelAssembly of the California two-spot Octopus

Coffing, G. C.; Tittes, S.; Small, S. T.; Songco-Casey, J. O.; Piscopo, D. M.; Pungor, J. R.; Miller, A. C.; Niell, C.; Kern, A. D.

10.1101/2024.02.21.581452 — evolutionary biology — Posted on 2024-02-21

1370 Leveraging the Red List of Ecosystems for national action on coral reefs through the Kunming-Montreal Global Biodiversity Framework

Gudka, M.; Obura, D.; Treml, E.; Samoilys, M.; Aboud, S. A.; Osuka, K.; Mbugua, J.; Mwaura, J.; Karisa, J.; Knoester, E.; Musila, P.; Omar, M.; Nicholson, E.

10.1101/2024.02.18.580850 — ecology — Posted on 2024-02-21

1371 Gut feeling: host and habitat as drivers of the microbiome in blackbuck (Antilope cervicapra)

Jana, A.; Roy, S.; Bagchi, S.; Isvaran, K.; Karanth, K. P.

10.1101/2024.02.20.581148 — ecology — Posted on 2024-02-21

1372 From local seafloor imagery to global patterns in benthic habitat states: contribution of citizen science to habitat classification across latitudes

Violet, C.; Boye, A.; Dubois, S.; Edgar, G. J.; Stuart-Smith, R. D.; Marzloff, M. P.

10.1101/2024.02.18.580891 — ecology — Posted on 2024-02-21

1373 Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4)

Kilpatrick, A. M.; Seidl, C. M.; Ipsaro, I. J.; Garrison, C. E.; Fabbri, G.; Howell, P. I.; McGowan, A. G.; White, B. J.; Mitchell, S. N.

10.1101/2024.02.16.580617 — ecology — Posted on 2024-02-21

1374 The moon's influence on the activity of tropical forest mammals

Bischof, R.; Vallejo Vargas, A. F.; Semper-Pascual, A.; Schowanek, S.; Beaudrot, L.; Turek, D.; Jansen, P. A.; Rovero, F.; Johnson, S. E.; Lima, M. G. M.; Santos, F.; Uzabaho, E.; Espinosa, S.; Ahumada, J. A.; Bitariho, R.; Salvador, J.; Mugerwa, B.; Sainge, M. N.; Sheil, D.

10.1101/2024.02.20.581159 — ecology — Posted on 2024-02-21

1375 Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis

Direder, M.; Laggner, M.; Copic, D.; Klas, K.; Bormann, D.; Schweiger, T.; Hoetzenecker, K.; Aigner, C.; Ankersmit, H. J.; Mildner, M.

10.1101/2024.02.19.580975 — developmental biology — Posted on 2024-02-21

1376 Hepatocyte differentiation requires anisotropic expansion of bile canaliculi

Belicova, L.; Bebelman, M.; Gralinska, E.; Jumel, T.; Lahree, A.; Shevchenko, A.; Zatsepin, T.; Kalaidzidis, Y.; Vingron, M.; Zerial, M.

10.1101/2024.02.19.581065 — developmental biology — Posted on 2024-02-21

1377 Single-nucleus multiomics reveals the gene-regulatory networks underlying sex determination of murine primordial germ cells

Alexander, A. K.; Rodriguez, K. F.; Chen, Y.-Y.; Amato, C.; Estermann, M. A.; Xu, X.; Yao, H.

10.1101/2024.02.19.581036 — developmental biology — Posted on 2024-02-21

1378 Membrane Bound O-Acyltransferase 7 (MBOAT7) Shapes Lysosomal Lipid Homeostasis and Function to Control Alcohol-Associated Liver Injury

Varadharajan, V.; Ramachandiran, I.; Massey, W. J.; Jain, R.; Banerjee, R.; Horak, A. J.; McMullen, M. R.; Huang, E.; Bellar, A.; Lorkowski, S. W.; Gulshan, K.; Helsley, R. N.; James, I.; Pathak, V.; Dasarathy, J.; Welch, N.; Dasarathy, S.; Streem, D.; Reizes, O.; Allende, D. S.; Smith, J. D.; Simcox, J.; Nagy, L. E.; Brown, J. M.

10.1101/2023.09.26.559533 — molecular biology — Posted on 2024-02-21

1379 Saccharomyces cerevisiae Rev7 regulates DSB repair pathway choice through binding and blocking Mre11 nuclease and Rad50 ATPase activities

Badugu, S.; Dhyani, K. M.; Thakur, M.; Muniyappa, K.

10.1101/2024.02.20.581217 — molecular biology — Posted on 2024-02-21

1380 Lessons from twenty years of the life of commensal Escherichia coli populations in a human gut

Condamine, B.; Morel-Journel, T.; Tesson, F.; Magnan, M.; Bernheim, A.; Denamur, E.; Blanquart, F.; Clermont, O.

10.1101/2024.02.21.581337 — microbiology — Posted on 2024-02-21

1381 High phenotypic and genotypic plasticity among strains of the mushroom-forming fungus Schizophyllum commune

Marian, I. M.; Valdes, I. D.; Hayes, R. D.; LaButti, K.; Duffy, K.; Chovatia, M.; Johnson, J.; Ng, V.; Lugones, L. G.; Wosten, H. A. B.; Grigoriev, I. V.; Ohm, R. A.

10.1101/2024.02.21.581338 — microbiology — Posted on 2024-02-21

1382 DO ORGANIC, CONVENTIONAL, AND INTENSIVE APPROACHES IN LIVESTOCK FARMING HAVE AN IMPACT ON THE CIRCULATION OF INFECTIOUS AGENTS? A SYSTEMATIC REVIEW, FOCUSED ON DAIRY CATTLE

Pajoro, M.; Brilli, M.; Pezzali, G.; Kramer, L. H.; Moroni, P.; Bandi, C.

10.1101/2024.02.20.581183 — microbiology — Posted on 2024-02-21

1383 Identification and characterization of a skin microbiome on Caenorhabditis elegans suggests environmental microbes confer cuticle protection

Haghani, N. B.; Lampe, R. H.; Samuel, B.; Chalasani, S. H.; Matty, M. A.

10.1101/2024.02.21.581412 — microbiology — Posted on 2024-02-21

1384 NR4A3 deficiency ameliorates contact hypersensitivity and exacerbates psoriasis by regulating gene expression in dendritic cells

Katagiri, M.; Ito, N.; Nagata, K.; Nakano, S.; Minamikawa, N.; Yamashita, N.; Takahashi, M.; Kurihara, M.; Nagaoka, M.; Ando, M.; Ito, T.; Yashiro, T.; Yoshimura, A.; Nishiyama, C.

10.1101/2024.02.20.581116 — immunology — Posted on 2024-02-21

1385 NeuroFreq: a MATLAB Toolbox for Time-Frequency Analysis of M/EEG Data

Rawls, E.

10.1101/2023.11.01.565154 — neuroscience — Posted on 2024-02-21

1386 Pathogenic tau induces an adaptive elevation in mRNA translation rate at early stages of disease

Zuniga, G.; Katsumura, S.; De Mange, J.; Ramirez, P.; Atrian, F.; Morita, M.; Frost, B.

10.1101/2024.02.19.581061 — neuroscience — Posted on 2024-02-21

1387 Polygenic Risk for Alcohol Use Disorder Affects Cellular Responses to Ethanol Exposure in a Human Microglial Cell Model

Li, X.; Liu, J.; Boreland, A.; Kapadia, S.; Zhang, S.; Stillitano, A.; Abbo, Y.; Clark, L.; Lai, D.; Li, Y.; Barr, P.; Meyers, J.; Kamarajan, c.; Kuang, W.; Agrawal, A.; Slesinger, P.; Dick, D.; Salvatore, J.; Tischfield, J.; Duan, J.; Edenberg, H.; Kreimer, A.; Hart, R. P.; Pang, Z. P.

10.1101/2024.02.19.581066 — neuroscience — Posted on 2024-02-21

1388 Communication with Surprise - Computational and Neural Mechanisms for Non-Verbal Human Interactions

Buidze, T.; Sommer, T.; Zhao, K.; Fu, X.; Glaescher, J. P.

10.1101/2024.02.20.581193 — neuroscience — Posted on 2024-02-21

1389 Stability of N-type inactivation and the coupling between N-type and C-type inactivation in the Aplysia Kv1 channel

Iwamuro, T.; Itohara, K.; Furukawa, Y.

10.1101/2024.02.19.581087 — physiology — Posted on 2024-02-21

1390 Alveolar macrophages play a key role in tolerance to ozone

Smith, G.; Nalesnik, M.; Immormino, R.; Simon, J.; Harkema, J. R.; Mock, J. R.; Moran, T. P.; Kelada, S. N. P.

10.1101/2024.02.18.580749 — pharmacology and toxicology — Posted on 2024-02-21

1391 Molecular dynamics simulations reveal molecular mechanisms for the gain and loss of function effects of four SCN2A variants

Bhattarai, N.; Montanucci, L.; Brunger, T.; Palma, E. P.; Martin, W.; Smith, I. N.; Eng, C.; Cheng, F.; Helbig, I.; Moller, R.; Brunklaus, A.; Schorge, S.; Lal, D.

10.1101/2024.02.19.580930 — biophysics — Posted on 2024-02-21

1392 RUDEUS, a machine learning classification system to study DNA-Binding proteins

Medina-Ortiz, D.; Cabas-Mora, G.; Moya-Barria, I.; Soto-Garcia, N.; Uribe-Paredes, R.

10.1101/2024.02.19.580825 — bioinformatics — Posted on 2024-02-21

1393 Finimizers: Variable-length bounded-frequency minimizers for k-mer sets

Alanko, J. N.; Biagi, E.; Puglisi, S. J.

10.1101/2024.02.19.580943 — bioinformatics — Posted on 2024-02-21

1394 Intrinsic Disorder and Salt-dependent Conformational Changes of the N-terminal TFIP11 Splicing Factor

Juniku, B.; Mignon, J.; Genco, A.; Obeid, A. M.; Mottet, D.; MONARI, A.; Michaux, C.

10.1101/2024.02.18.580885 — bioinformatics — Posted on 2024-02-21

1395 New, biomechanically sound tendon tissue after injection of uncultured, autologous, adipose derived regenerative cells in partial Achilles tendon defects in rabbits

Schmitz, C.; Alt, C.; Wuerfel, T.; Milz, S.; Dinzey, J.; Hill, A.; Sikes, K. J.; Burton, L.; Easley, J.; Stewart, H. L.; Puttlitz, C.; Gadomski, B. C.; Labus, K.; Pearce, D. A.; Maffulli, N.; Alt, E. U.

10.1101/2024.02.18.580890 — bioengineering — Posted on 2024-02-21

1396 Functional avidity of anti-B7H3 CAR-T constructs predicts antigen density thresholds for triggering effector function

Barisa, M.; Zappa, E.; Muller, H.; Shah, R.; Buhl, J.; Draper, B.; Himsworth, C.; Bowers, C.; Munnings-Tomes, S.; Nicolaidou, M.; Morlando, S.; Birley, K.; Leboreiro-Babe, C.; Vitali, A.; Privitera, L.; O'Sullivan, K.; Greppi, A.; Buschhaus, M.; Barrera Roman, M.; de Blank, S.; van den Ham, F.; van 't Veld, B. R.; Ferry, G.; Donovan, L. K.; Chesler, L.; Molenaar, J. J.; Drost, J.; Rios, A. C.; Chester, K.; Wienke, J.; Anderson, J.

10.1101/2024.02.19.580939 — bioengineering — Posted on 2024-02-21

1397 A Model of Ethanol Self-Administration in Head-Fixed Mice

Ward, A. L.; Winston, K. T.; Buchmaier, S. A.; Clarke, R. E.; Bell, M. S.; Martino, M. R.; Vollmer, K. M.; Paniccia, J.; Doncheck, E. M.; Grant, R. I.; Otis, J. M.; Rinker, J. A.

10.1101/2024.02.17.580838 — animal behavior and cognition — Posted on 2024-02-21

1398 Asynchronous haltere input drives specific wing and head movements in Drosophila

Rauscher, M. J.; Fox, J. L.

10.1101/2022.09.29.509061 — animal behavior and cognition — Posted on 2024-02-21

1399 Genomic 8-oxoguanine modulates gene transcription independent of its repair by DNA glycosylases OGG1 and MUTYH

Obermann, T.; Sakshaug, T.; Kanagaraj, V. V.; Abentung, A.; Sarno, A.; Bjoras, M.; Scheffler, K.

10.1101/2024.02.20.581185 — genomics — Posted on 2024-02-21

1400 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.

10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-21

1401 Playing with the ploidy level enables to switch on and off the strict recombination control even in the vicinity of Brassica centromeres

Boideau, F.; Huteau, V.; Brunet, A.; Maillet, L.; Coriton, O.; Trotoux, G.; Lode-Taburel, M.; Deniot, G.; Eber, F.; Gilet, M.; Boutte, J.; Morice, J.; Falentin, C.; Martin, O.; Falque, M.; Chevre, A.-M.; Rousseau-Gueutin, M.

10.1101/2024.02.19.580878 — genetics — Posted on 2024-02-21

1402 The acoustic adaptation hypothesis across terrestrial vertebrates: a meta-analysis

Freitas, B.; D'Amelio, P. B.; Mila, B.; Thebaud, C.; Janicke, T.

10.1101/2024.02.21.581368 — evolutionary biology — Posted on 2024-02-21

1403 Developmental synchrony and extraordinary multiplication rates in pathogenic organisms

Greischar, M. A.; Childs, L. M.

10.1101/2024.02.19.580990 — ecology — Posted on 2024-02-21

1404 Novel mathematical morphology model identifies dorsal-ventral asymmetry of endothelial cell morphology in dorsal aorta of wild-type and Endoglin-deficient zebrafish embryos

Seeler, D.; Grdseloff, N.; Rodel, C. J.; Kloft, C.; Abdelilah-Seyfried, S.; Huisinga, W.

10.1101/2024.02.19.580931 — developmental biology — Posted on 2024-02-21

1405 Multilevel proteomic profiling of colorectal adenocarcinoma cell differentiation to characterize an intestinal epithelial model

Fekete, E. E.; Wang, A.; Creskey, M.; Cummings, S. E.; Lavoie, J. R.; Ning, Z.; Li, J.; Figeys, D.; Chen, R.; ZHANG, X.

10.1101/2024.02.19.581096 — systems biology — Posted on 2024-02-21

1406 Effect of alpha-tubulin acetylation on the doublet microtubule structure

Yang, S. K.; Kubo, S.; Black, C. S.; Peri, K.; Dai, D.; Legal, T.; Valente-Paterno, M.; Gaertig, J.; Bui, K. H.

10.1101/2023.09.21.558788 — cell biology — Posted on 2024-02-21

1407 Importance of environmental signals for proper cardiac morphological development in Atlantic salmon

Johansen, I. B.; Vindas, M. A.; Engdal, V. A.; Kavaliauskiene, S.; Folkedal, O.; Hoglund, E.; Moyano, M.; Overli, O.; Frisk, M.

10.1101/2024.02.19.580955 — physiology — Posted on 2024-02-21

1408 Oxygen carrying nanoemulsions and respiratory hyperoxia eliminate tumor hypoxia-induced suppression and improve cancer immunotherapy

Halpin-Veszeleiova, K.; Mallouh, M.; Apro, A.; Romero, N.; Bahr, C.; Shin, M.; Ward, K.; Rosenberg, L.; Sitkovsky, M.; Spiess, B.; Hatfield, S. M.

10.1101/2024.02.17.580835 — immunology — Posted on 2024-02-21

1409 Episodic recruitment of attractor dynamics in frontal cortex reveals distinct mechanisms for forgetting and lack of cognitive control in short-term memory

Ona-Jodar, T.; Prat-Ortega, G.; Li, C.; Dalmau, J.; Compte, A.; de la Rocha, J.

10.1101/2024.02.18.579447 — neuroscience — Posted on 2024-02-21

1410 Large-scale deorphanization of Nematostella vectensis neuropeptide GPCRs supports the independent expansion of bilaterian and cnidarian peptidergic systems

Thiel, D.; Yanez-Guerra, L. A.; Kieswetter, A.; Cole, A. G.; Temmerman, L.; Technau, U.; Jekely, G.

10.1101/2023.07.03.547448 — neuroscience — Posted on 2024-02-21

1411 Nerve injury downregulates δ-opioid and cannabinoid CB1 receptor genes through REST in primary sensory neurons

Subedi, A.; Tiwari, A.; Etemad, A. F.; Huang, Y.; Chatterjee, B.; McLeod, S. L.; Lu, Y.; Gonzalez, D.; Ghosh, K.; Singh, S. K.; Ruiz Echartea, M. E.; Grimm, S. L.; Coarfa, C.; Pan, H.-L.; Majumder, S.

10.1101/2024.02.17.579842 — neuroscience — Posted on 2024-02-21

1412 Towards robust and generalizable representations of extracellular data using contrastive learning

Vishnubhotla, A.; Loh, C.; Paninski, L.; Srivastava, A.; Hurwitz, C. L.

10.1101/2023.10.30.564831 — neuroscience — Posted on 2024-02-21

1413 The effects of clay minerals on bacterial community composition during arthropod decay

Corthesy, N.; Saleh, F.; Thomas, C.; Antcliffe, J. B.; Daley, A. C.

10.1101/2024.02.19.580992 — paleontology — Posted on 2024-02-21

1414 Unveiling neoadjuvant chemotherapy-induced immune landscape remodeling and metabolic reprogramming in lung adenocarcinoma by scRNA-sequencing

Huang, Y.; Cheng, L.; Bi, G.; Liang, J.; Li, M.; Zhang, H.; Shan, G.; Hu, Z.; Chen, Z.; Wu, G.; Lin, Z.; Jiang, W.; Wang, Q.; XI, J.; Zhan, C.; Yin, S.

10.1101/2024.02.18.580893 — cancer biology — Posted on 2024-02-21

1415 Base-Assisted Mechanism of Acrylamide Reactions With Cysteines: QM/MM Simulations of Afatinib Reaction with EGFR

Ma, S.; Patel, H.; Peeples, C. A.; Shen, J.

10.1101/2024.02.18.580887 — biophysics — Posted on 2024-02-21

1416 Molecular Architecture of Chitin and Chitosan-Dominated Cell Walls in Zygomycetous Fungal Pathogens by Solid-State NMR

Cheng, Q.; Dickwella Widanage, M. C.; Yarava, J. R.; Latge, J.-P.; Wang, P.; Wang, T.

10.1101/2024.02.19.581103 — biophysics — Posted on 2024-02-21

1417 Simulating Colloid Motion in Spinning Suspension: Internal Dynamics in Orbital Shaker

Zhao, N.; Zheng, D.

10.1101/2024.02.19.581033 — biophysics — Posted on 2024-02-21

1418 TUnA: An uncertainty aware transformer model for sequence-based protein-protein interaction prediction

Ko, Y. S.; Parkinson, J.; Liu, C.; Wang, W.

10.1101/2024.02.19.581072 — bioinformatics — Posted on 2024-02-21

1419 Enhanced Protein-Protein Interaction Discovery via AlphaFold-Multimer

Kim, A.-R.; Hu, Y.; Comjean, A.; Rodiger, J.; Mohr, S. E.; Perrimon, N.

10.1101/2024.02.19.580970 — bioinformatics — Posted on 2024-02-21

1420 Nitrogen metabolism in the picoalgae Pelagomonas calceolata: disentangling cyanate lyase function under different nutrient conditions.

Guerin, N.; Seyman, C.; Orvain, C.; Bertrand, L.; Gourvil, P.; Probert, I.; Vacherie, B.; Brun, E.; Magdelenat, G.; Labadie, K.; Wincker, P.; Thurotte, A.; Carradec, Q.

10.1101/2024.02.19.580968 — genomics — Posted on 2024-02-21

1421 A single E205D allele of a key P450 CYP6P3 is driving metabolic pyrethroid resistance in the major African malaria vector Anopheles gambiae

Kengne-Ouafo, J. A.; Kouamo, M.; Muhammad, A.; Tepa, A.; Ntadoun, S.; Mugenzi, L.; Tekoh, T.; Hearn, J.; Tchouakui, M.; Wondji, M.; Ibrahim, S. S.; Wondji, C. S.

10.1101/2024.02.18.580859 — genomics — Posted on 2024-02-21

1422 Transcriptome sequencing and bioinformatics analysis of kidney tissue in a tree shrew model of calcium oxalate nephrolithiasis

Wang, G.; Huang, Z.; Wu, Y.; Xu, R.; Li, J.

10.1101/2024.02.18.580876 — genomics — Posted on 2024-02-21

1423 Adaptive predictor-set linear model: an imputation-free method for linear regression prediction on datasets with missing values

Jimenez, B. P.; Kayser, M.; Vidaki, A.; Caliebe, A.

10.1101/2024.02.19.581027 — genetics — Posted on 2024-02-21

1424 Using runs of homozygosity and machine learning to disentangle sources of inbreeding and infer self-fertilization rates

Zeitler, L.; Gilbert, K. J.

10.1101/2024.02.20.581206 — genetics — Posted on 2024-02-21

1425 Effective Population Size in Field Pea

Johnson, J. P.; Piche, L.; Worral, H.; Atanda, S. A.; Coyne, C. J.; McGee, R.; McPhee, K.; Bandillo, N.

10.1101/2024.02.19.581041 — genetics — Posted on 2024-02-21

1426 Urbanization is associated with reduced genetic diversity in marine fish populations

Karachaliou, E.; Schmidt, C.; de Greef, E.; Docker, M. F.; Garroway, C. J.

10.1101/2024.02.20.581210 — evolutionary biology — Posted on 2024-02-21

1427 Predicting species invasiveness with genomic data: is Genomic Offset related to establishment probability?

Camus, L.; Boitard, S.; Gautier, M.

10.1101/2024.02.20.581132 — evolutionary biology — Posted on 2024-02-21

1428 Can we predict the predation pressure of owned domestic cats on all birds in the United States?

Philippe-Lesaffre, M.

10.1101/2024.02.19.580995 — ecology — Posted on 2024-02-21

1429 Combining radio-telemetry and radar measurements to test optimal foraging in an aerial insectivore bird

Bloch, I.; Troupin, D.; Toledo, S.; Nathan, R.; Sapir, N.

10.1101/2024.02.18.580922 — ecology — Posted on 2024-02-21

1430 A pre-vertebrate endodermal origin of calcitonin-producing neuroendocrine cells

Rees, J. M.; Kirk, K.; Gattoni, G.; Hockman, D.; Ritter, D. J.; Benito Gutierrez, E.; Knapik, E.; Crump, J. G.; Fabian, P.; Gillis, J. A.

10.1101/2024.02.17.580846 — developmental biology — Posted on 2024-02-21

1431 The Co-Evolution of Jawed Vertebrates and Interferon Regulatory Factor 5 Generates Unique Inflammation and Innate Immunity

Hubing, V.; Marquis, A.; Ziemann, C.; Moriyama, H.; Moriyama, E.; Zhang, L.

10.1101/2024.02.19.581058 — immunology — Posted on 2024-02-21

1432 Alternative Macrophage Activation Requires Granulocyte-Derived Lipids

Veremeyko, T.; Vik, A.; Hansen, T. V.; Ponomarev, E. D.

10.1101/2024.02.17.580795 — immunology — Posted on 2024-02-21

1433 Human lymphoid-neutrophil/monocyte restriction co-ordinately activates increased proliferation despite parallel heterogeneity in transcriptional changes

Wang, F.; Campos, L. G.; Hammond, C.; Hirst, M.; Simons, B. D.; Eaves, C. J.

10.1101/2024.02.18.580894 — immunology — Posted on 2024-02-21

1434 Real-time activity of dynorphin-expressing neurons in mouse central amygdala during alcohol drinking

Lebonville, C.; Rinker, J. A.; O'Hara, K.; McMahan, C.; Hoffman, M.; Becker, H.; Mulholland, P. J.

10.1101/2024.02.18.580880 — neuroscience — Posted on 2024-02-21

1435 Differential weighting of information during aloud and silent reading: Evidence from representational similarity analysis of fMRI data

Bailey, L. M.; Matheson, H. E.; Fawcett, J. M.; Bodner, G. E.; Newman, A. J.

10.1101/2024.02.18.580744 — neuroscience — Posted on 2024-02-21

1436 POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons in the female mouse

Talbi, R.; Stincic, T. L.; Ferrari, K.; Ji Hae, C.; Walec, K.; Medve, E.; Gerutshang, A.; Leon, S.; McCarthy, E. A.; Ronnekleiv, O. K.; Kelly, M. J.; Navarro, V. M.

10.1101/2024.02.18.580873 — neuroscience — Posted on 2024-02-21

1437 The bispectral EEG (BSEEG) method quantifies post-operative delirium-like states in young and aged mice after head mount implantation surgery

Nishiguchi, T.; Shibata, K.; Yamanishi, K.; Dittrich, M. N.; Islam, N. Y.; Patel, S.; Phuong, N. J.; Marra, P. S.; Malicoat, J. R.; Yamanashi, T.; Nishizawa, Y.; Seki, T.; Iwata, M.; Shinozaki, G.

10.1101/2024.02.17.580752 — neuroscience — Posted on 2024-02-21

1438 Range of Ixodes laguri, a nidicolous tick that parasitizes critically endangered rodents, with details on its western distribution limit in Austria

Rubel, F.

10.1101/2024.02.20.581178 — zoology — Posted on 2024-02-21

1439 Aedes albopictus is not an arbovirus aficionado - Impacts of sylvatic flavivirus infection in vectors and hosts on mosquito engorgement on non-human primates

Cecilia, H.; Althouse, B. M.; Azar, S. R.; Moehn, B. A.; Yun, R.; Rossi, S. L.; Vasilakis, N.; Hanley, K. A.

10.1101/2024.02.19.580944 — systems biology — Posted on 2024-02-21

1440 Lysis buffer selection guidance for mass spectrometry-based global proteomics including studies on the intersection of signal transduction and metabolism

Helm, B.; Hansen, P.; Lai, L.; Schwarzmuller, L.; Clas, S. M.; Richter, A.; Ruwolt, M.; Liu, F.; Frey, D.; DAlessandro, L. A.; Lehmann, W. D.; Schilling, M.; Helm, D.; Fiedler, D.; Klingmuller, U.

10.1101/2024.02.19.580971 — systems biology — Posted on 2024-02-21

1441 PeakPerformance - A software tool for fitting LC-MS/MS peaks including uncertainty quantification by Bayesian inference

Niesser, J.; Osthege, M.; von Lieres, E.; Wiechert, W.; Noack, S.

10.1101/2024.02.17.580815 — systems biology — Posted on 2024-02-21

1442 Mating-compatibility genes employed as diagnostic markers to identify novel incursions of the myrtle rust pathogen Austropuccinia psidii

Feng, J.; Bird, A.; Luo, Z.; Sheperd, L.; Murphy, L.; Singh, L.; Graetz, A.; Moeller, M.; Amorim, L.; Massola Junior, N. S.; Prodhan, A.; Shuey, L.; Beattie, D.; Gonzalez, A. T.; Tobias, P. A.; Padovan, A.; Kimber, R.; McTaggart, A.; Kehoe, M.; Schwessinger, B.; Boufleur, T. R.

10.1101/2024.02.19.580897 — plant biology — Posted on 2024-02-21

1443 MicroRNA-26b protects against MASH development and can be efficiently targeted with lipid nanoparticles.

Peters, L.; Rakateli, L.; Huchzermeier, R.; Bonnin-Marquez, A.; Maas, S. L.; Lin, C.; Jans, A.; Geng, Y.; Gorter, A.; Gijbels, M.; Rensen, S.; Olinga, P.; Hendrikx, T.; Krawczyk, M.; Brisbois, M.; Jankowski, J.; Bidzhekov, K.; Weber, C.; Biessen, E. A. L.; Shiri-Sverdlov, R.; Houben, T.; Doering, Y.; Bartneck, M.; van der Vorst, E. P. C.

10.1101/2024.02.18.580792 — pathology — Posted on 2024-02-21

1444 Spatial Transcriptomics in Breast Cancer Reveals Tumour Microenvironment-Driven Drug Responses and Clonal Therapeutic Heterogeneity

Jimenez-Santos, M. J.; Garcia-Martin, S.; Rubio-Fernandez, M.; Gomez-Lopez, G.; Al-Shahrour, F.

10.1101/2024.02.18.580660 — cancer biology — Posted on 2024-02-21

1445 Epigallocatechin-3-gallate inhibit the protein arginine methyltransferase 5 and Enhancer of Zeste homolog 2 in breast cancer both in vitro and in vivo

Nalla, K.; Chatterjee, B.; Poyya, J.; Swain, A.; Ghosh, K.; Pan, A.; Joshi, C. G.; Manavathi, B.; Kanade, S. R.

10.1101/2024.02.18.580855 — cancer biology — Posted on 2024-02-21

1446 Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells

Santiappillai, N.; Cao, Y.; Hakeem-Sanni, M. F.; Yang, J. Y. H.; Quek, L.-E.; Hoy, A. J.

10.1101/2024.02.18.580900 — cancer biology — Posted on 2024-02-21

1447 Guidelines for QSM phantom production and evaluation ofcandidate phantom materials

Hooper, P.; Jin, J.; O'Brien, K.; Tourell, M.; Robinson, S. D.; Barth, M.

10.1101/2024.02.18.580843 — biophysics — Posted on 2024-02-21

1448 Random sampling of ligand arrangements on a one-dimensional lattice

Mohanta, D.; Dvirnas, A.; Ambjörnsson, T.

10.1101/2024.02.17.580696 — biophysics — Posted on 2024-02-21

1449 Ensemble automated approaches for producing high quality herbarium digital records

Guralnick, R. P.; LaFrance, R.; Allen, J.; Denslow, M.

10.1101/2024.02.19.580800 — bioinformatics — Posted on 2024-02-21

1450 Computational analysis of the effect of a binding protein (RbpA) on the dynamics of Mycobacterium tuberculosis RNA polymerase assembly

Ramanathan, S.; Bheemireddy, S.; Srinivasan, N.

10.1101/2024.02.19.580928 — bioinformatics — Posted on 2024-02-21

1451 Annotation and visualisation of parasite, fungi and arthropod genomes with Companion

Haese-Hill, W.; Crouch, K.; Otto, T. D.

10.1101/2024.02.19.580948 — bioinformatics — Posted on 2024-02-21

1452 Compositional transformations can reasonably introduce phenotype-associated values into sparse features

Austin, G. I.; Korem, T.

10.1101/2024.02.19.581060 — bioinformatics — Posted on 2024-02-21

1453 Alterations in genes associated with cytosolic RNA sensing in whole blood are associated with coronary microvascular disease in SLE

Huo, L.; Montano, E.; Tumurkhuu, G.; Bose, M.; Berman, D. S.; Wallace, D.; Wei, J.; Ishimori, M.; Merz, C. N. B.; Jefferies, C.

10.1101/2024.02.19.580713 — bioinformatics — Posted on 2024-02-21

1454 Investigating the use of odour and colour foraging cues by rosy-faced lovebirds (Agapornis roseicollis) using deep-learning based behavioural analysis

Tsang, W. K. W.; Poon, E. S. K.; Newman, C.; Buesching, C. D.; Sin, S. Y. W.

10.1101/2024.02.18.580921 — animal behavior and cognition — Posted on 2024-02-21

1455 Non-Invasive dsRNA Delivery via Feeding for Effective Gene Silencing in Teleost Fish: A Novel Approach in the Study of Gene Function Analysis

Gao, X.; Liu, X.; Yang, R.; Song, W.; Shen, Y.; Sun, H.; Nie, T.; Yue, X.; Song, Z.; Qi, J.; Zhang, Q.; He, Y.

10.1101/2024.02.19.580956 — genetics — Posted on 2024-02-21

1456 Biallelic pathogenic variants in DNAH3 cause male infertility in humans and mice

Wang, X.; Shen, G.; Yang, Y.; Jiang, C.; Ruan, T.; Yang, X.; Zhuo, L.; Zhang, Y.; Ou, Y.; Zhao, X.; Long, S.; Tang, X.; Lin, T.; Shen, Y.

10.1101/2024.02.19.580977 — genetics — Posted on 2024-02-21

1457 The evolution of antibiotic resistance islands occurs within the framework of plasmid lineages

Wang, Y.; Dagan, T.

10.1101/2024.02.20.581145 — evolutionary biology — Posted on 2024-02-21

1458 Mutations in iclR increase evolvability by facilitating compensation that exposes cryptic beneficial mutations in experimental populations of Escherichia coli

Staples, R. K.; Cooper, T. F.

10.1101/2024.02.21.581449 — evolutionary biology — Posted on 2024-02-21

1459 Social-ecological models with social hierarchy and spatial structure applied to small scale fisheries

Wulfing, S.; White, E. R.

10.1101/2024.02.17.580847 — ecology — Posted on 2024-02-21

1460 Stochastic regimes can hide the attractors in data, reconstruction algorithms can reveal them

M.S. Arani, B.; R. Carpenter, S.; H. van Nes, E.; A. van de Leemput, I.; Xu, C.; G. Lind, P.; Scheffer, M.

10.1101/2024.02.17.580797 — ecology — Posted on 2024-02-21

1461 Temporal characterization of the viral load of psittacine beak and feather disease virus in rosy-faced lovebirds (Agapornis roseicollis)

Lam, D. K.; Poon, E. S. K.; Sin, S. Y. W.

10.1101/2024.02.19.581011 — ecology — Posted on 2024-02-21

1462 Turgor and the conformational pathway for MscS recovery

Anishkin, A.; Sukharev, S. I.

10.1101/2024.02.18.580915 — biophysics — Posted on 2024-02-21

1463 Tree sequences as a general-purpose tool for population genetic inference

Whitehouse, L. S.; Ray, D. D.; Schrider, D. R.

10.1101/2024.02.20.581288 — evolutionary biology — Posted on 2024-02-21

1464 Metadichol induced expression of circadian clock transcription factors in human fibroblasts.

Raghavan, P. R.

10.1101/2024.02.21.581403 — cell biology — Posted on 2024-02-21

1465 Sarcomeric SRX:DRX Equilibrium in Alport and LDLR/P407 Mouse Models of HFpEF.

Kamiar, A.; Williams, M. M.; Capcha, J. M. C.; Kazmierczak, K.; Liang, J.; Lopaschuk, G. D.; Webster, K. A.; Szczesna-Cordary, D.; Shehadeh, L. A.

10.1101/2024.02.20.581314 — cell biology — Posted on 2024-02-21

1466 Potential of Photoelectric Stimulation with Ultrasmall Carbon Electrode on Neural Tissue: New Directions in Neuromodulation Technology Development

Chen, K.; Wu, B.; Krahe, D.; Vazquez, A. L.; Siegenthaler, J.; Li, W.; Cui, X. T.; Kozai, T. D. Y.

10.1101/2024.02.17.580823 — bioengineering — Posted on 2024-02-21

1467 Hist2Cell: Deciphering Fine-grained Cellular Architectures from Histology Images

ZHAO, W.; LIANG, Z.; HUANG, X.; Huang, Y.; Yu, L.

10.1101/2024.02.17.580852 — bioengineering — Posted on 2024-02-21

1468 Assessment of the Epigenomic Landscape in Human Myometrium at Term Pregnancy

Wu, S. P. S.; Quiroz, E.; Wang, T.; Redecke, S. M.; Xu, X.; Lin, L.; Anderson, M.; DeMayo, F.

10.1101/2024.02.19.581035 — cell biology — Posted on 2024-02-21

1469 Predicting cell type-specific extracellular vesicle biology using an organism-wide single cell transcriptomic atlas - insights from the Tabula Muris

LaRocca, T.; Lark, D.

10.1101/2024.02.19.580983 — cell biology — Posted on 2024-02-21

1470 nERdy: network analysis of endoplasmic reticulum dynamics

Samudre, A.; GAO, G.; Cardoen, B.; Nabi, I. R.; Hamarneh, G.

10.1101/2024.02.20.581259 — cell biology — Posted on 2024-02-21

1471 Expansion microscopy reveals unique ultrastructural features of pathogenic budding yeast species

Reza, M. H.; Dutta, S.; Goyal, R.; Shah, H.; Dey, G.; Sanyal, K.

10.1101/2024.02.20.581313 — cell biology — Posted on 2024-02-21

1472 TFEB controls syncytiotrophoblast differentiation

Esbin, M. N.; Dahal, L.; Fan, V. B.; McKenna, J. K.; Yin, E.; Darzacq, X.; Tjian, R.

10.1101/2024.02.20.581304 — cell biology — Posted on 2024-02-21

1473 Effects of tenascin-C on dental pulp tissue in mice in vivo and on the proliferation and differentiation of dental pulp stem cells into odontoblasts and calcification in vitro

Kojima, K.; Akashi, Y.; Nakajima, K.; Kokubun, K.; Shintani, S.; Matsuzaka, K.

10.1101/2024.02.19.580638 — cell biology — Posted on 2024-02-21

1474 Theileria annulata Infection Promotes p53 suppression, Genomic Instability and DNA deaminase APOBEC3H upregulation leading to cancer-like phenotype in host cells

sharma, p.; Dandesena, D.; suresh, a.; Budhwar, R.; Godwin, J.; singh, s.; Subudhi, M.; T, A.; roy, s.; A, V. M.; bhandari, v.

10.1101/2024.02.20.581323 — cell biology — Posted on 2024-02-21

1475 Systematic mapping of MCU-mediated mitochondrial calcium signaling networks

Delgado de la Herran, H. C.; Reane, D. V.; Cheng, Y.; Katona, M.; Hosp, F.; Greotti, E.; Wettmarshausen, J.; Patron, M.; Mohr, H.; Prudente de Mello, N.; Chudenkova, M.; Gorza, M.; Walia, S.; Feng, M. S.-F.; Leimpek, A.; Mielenz, D.; Pellegata, N. S.; Langer, T.; Hajnoczky, G.; Mann, M.; Murgia, M.; Perocchi, F.

10.1101/2024.02.20.581153 — cell biology — Posted on 2024-02-21

1476 Lysine Demethylase 4A is a Centrosome Associated Protein Required for Centrosome Integrity and Genomic Stability

Chowdhury, P.; Wang, X.; Love, J. F.; Vargas-Hernandez, S.; Nakatani, Y.; Grimm, S. L.; Mezquita, D.; Mason, F. M.; Martinez, E. D.; Coarfa, C.; Walker, C. L.; Gustavsson, A.-K.; Dere, R.

10.1101/2024.02.20.581246 — cell biology — Posted on 2024-02-21

1477 FSTL1 is an antagonist of ERK1/2 phosphorylation during ciliogenesis and preadipocyte differentiation.

Santos, L.; Guggeri, L.; Escande, C.; Badano, J. L.; Prieto-Echague, V.

10.1101/2024.02.21.581425 — cell biology — Posted on 2024-02-21

1478 Arginine Di-methylation of RIPK3 Safeguards Necroptosis for Intestinal Homeostasis

Zhang, J.; Zhao, P.; Dan, H.; Wang, Y.; Chen, X.; Jiang, X.; Shen, Y.; Wang, J.; Yang, Z.; Zhao, J.; Zhang, Y.; Zheng, J.; Liu, W.

10.1101/2024.02.21.581356 — cell biology — Posted on 2024-02-21

1479 Multiplexed dynamic control of temperature to probe and observe mammalian cells.

Benman, W.; Iyengar, P.; Mumford, T.; Bugaj, L.

10.1101/2024.02.18.580877 — bioengineering — Posted on 2024-02-21

1480 The Alexander Disease Protein GFAP Drives Mitochondrial Fission

XIONG, D.; KONG, L.; Tan, Y. S.; YUAN, F.; SUN, Z.; LI, X.; ABELLA, E.; MESSING, A.; Zhang, S.-C.

10.1101/2024.02.20.581117 — cell biology — Posted on 2024-02-21

1481 Regionalized cell and gene signatures govern oesophageal epithelial homeostasis

Grommisch, D.; Lund, H.; Eenjes, E.; Julien, A.; Goeritz, C.; Harris, R. A.; Sandberg, R.; Hagemann-Jensen, M.; Genander, M.

10.1101/2024.02.21.581361 — cell biology — Posted on 2024-02-21

1482 Identification of SEC61B as a novel regulator of calcium flux and platelet hyperreactivity in diabetes mellitus

Kong, Y. X.; Rehan, R.; Moreno, C. L.; Madsen, S.; Zhang, Y.; Zhao, H.; Cartland, S. P.; Houlahan, C. B.; Robertshaw, D.; Trang, V.; Ong, F. J. L.; Cielesh, M.; Cooke, K. C.; Potter, M.; Stockli, J.; Morahan, G.; Kalev-Zylinska, M.; Rondina, M. T.; Schulman, S.; Yang, J. Y. H.; Neely, G. G.; James, D. E.; Kavurma, M.; Hocking, S. L.; Twigg, S.; Weaver, J.; Larance, M.; Passam, F. H.

10.1101/2024.02.20.581175 — cell biology — Posted on 2024-02-21

1483 STING contributes to pulmonary hypertension by targeting the interferon and BMPR2 signaling through regulating F2RL3

Deng, L.; Cao, C. r.; Cai, Z. y.; Wang, Z. p.; Leng, B.; Kong, F. h.; zhou, Z. y.; He, J.; Nie, X. w.; Bian, J. s.

10.1101/2024.02.20.578386 — cell biology — Posted on 2024-02-21

1484 Modulation of stress granule dynamics by phosphorylation and ubiquitination in plants

He, S.-L.; Wang, X.; Kim, S.; Kong, L.; Wang, L.; He, P.; Shan, L.; Wang, Y.; Jang, J.-C.

10.1101/2024.02.20.581253 — cell biology — Posted on 2024-02-21

1485 β2 integrins impose a mechanical checkpoint on macrophage phagocytosis

Settle, A. H.; Winer, B. Y.; de Jesus, M. M.; Seeman, L.; Wang, Z.; Chan, E.; Romin, Y.; Zhuoning, L.; Miele, M. M.; Hendrickson, R. C.; Vorselen, D.; Perry, J. S. A.; Huse, M.

10.1101/2024.02.20.580845 — cell biology — Posted on 2024-02-21

1486 Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology

Cabalo, D. G.; Dekraker, J.; Royer, J.; Xie, K.; Tavakol, S.; Rodriguez - Cruces, R.; Bernasconi, A.; Bernasconi, N.; Weil, A.; Pana, R.; Frauscher, B.; Caciagli, L.; Jefferies, E.; Smallwood, J.; Bernhardt, B.

10.1101/2023.09.28.560002 — neuroscience — Posted on 2024-02-21

1487 Cingulate cortex shapes early postnatal development of social vocalizations

Nagarajan, G.; Matrov, D.; Pearson, A. C.; Yen, C.; Bradley, S. P.; Chudasama, Y.

10.1101/2024.02.17.580738 — neuroscience — Posted on 2024-02-21

1488 Glutamate as a co-agonist for acid-sensing ion channels to aggravate ischemic brain damage

Lai, K.; Pritisanac, I.; Liu, Z.-Q.; Liu, H.-W.; Gong, L.-N.; Li, M.-X.; Lu, J.-F.; Qi, X.; Xu, T.-L.; Forman-Kay, J. D.; Shi, H.-B.; Wang, L.-Y.; Yin, S.

10.1101/2024.02.17.580727 — neuroscience — Posted on 2024-02-21

1489 Associations between regional blood-brain barrier disruption, aging, and Alzheimers disease biomarkers in cognitively normal older adults

Denkinger, M.; Baker, S.; Inglis, B.; Kobayashi, S.; Juarez, A.; Mason, S.; Jagust, W.

10.1101/2024.02.16.580788 — neuroscience — Posted on 2024-02-21

1490 Exploring an EM-algorithm for banded regression in computational neuroscience

Fuglsang, S. A.; Madsen, K. H.; Puonti, O.; Siebner, H. R.; Hjortkjaer, J.

10.1101/2023.09.22.558945 — neuroscience — Posted on 2024-02-21

1491 Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity

Chevalier, S.; Decourt, M.; Francheteau, M.; Balbous, A.; Fernagut, P.-O.; Benoit-Marand, M.

10.1101/2024.02.17.580817 — neuroscience — Posted on 2024-02-21

1492 Accumulation of Oncogenic Mutations During Progression from Healthy Tissue to Cancer

Zhang, R.; Bozic, I.

10.1101/2024.02.18.580841 — cancer biology — Posted on 2024-02-21

1493 Comparison of Tug-of-War Models Assuming Moran versus Branching Process Population Dynamics

Dinh, K. N.; Kurpas, M. K.; Kimmel, M.

10.1101/2023.10.20.563302 — cancer biology — Posted on 2024-02-21

1494 Mechano-inhibition of Endocytosis Sensitizes Cancer Cells to Fas-induced Apoptosis

Kural, M.; Djakbarova, U.; Cakir, B.; Tanaka, Y.; Madraki, Y.; Chan, E. T.; Arteaga Muniz, V.; Qian, H.; Park, J.; Sewanan, L.; Park, I.-H.; Niklason, L.; Kural, C.

10.1101/2022.06.14.496195 — cancer biology — Posted on 2024-02-21

1495 A comprehensive map of transient protein-protein interactions and their structural features in the E. coli 1-carbon metabolism pathway

Bhattacharyya, S.; Ranganathan, S.; Chowdhury, S.; ADKAR, B. V.; Khrapko, M.; Shakhnovich, E.

10.1101/2024.02.17.580827 — biophysics — Posted on 2024-02-21

1496 Algorithmic construction of topologically complex biomineral lattices via cellular syncytia

Vyas, P.; Brannon, C. M.; Formery, L.; Lowe, C.; Prakash, M.

10.1101/2024.02.20.580924 — biophysics — Posted on 2024-02-21

1497 The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride.

Jiang, N.; Gelfond, J.; Liu, Q.; Strong, R.; Nelson, J. F.

10.1101/2024.02.17.579363 — bioinformatics — Posted on 2024-02-21

1498 Unveiling Inter-Embryo Variability in Spindle Length over time: towards Quantitative Phenotype Analysis.

10.1101/2023.05.01.538870 — bioinformatics — Posted on 2024-02-21

1499 Discovery of free glycated amines and glycated urea as potential markers of diabetic nephropathy

Shaikh, R. Q.; Das, S.; Chaurasiya, A. H.; Ashtamy, M. G.; Sheikh, A. B.; Fernandes, M.; Tiwari, S.; Unnikrishnan, A. G.; Kulkarni, M.

10.1101/2024.02.17.580794 — biochemistry — Posted on 2024-02-21

1500 Multi-trait multi-environment genomic prediction of preliminary yield trials in pulse crops

Saludares, R. A. G.; Atanda, S. A.; Piche, L.; Worral, H.; Dariva, F.; McPhee, K.; Bandillo, N.

10.1101/2024.02.18.580909 — genomics — Posted on 2024-02-21

1501 Mimicking Human EED Variants in Drosophila: A Promising Strategy to Analyze Human EED Variant Function

Cyrus, S. S.; Giro, S. M.; Lian, T.; Allan, D. W.; Gibson, W. T.

10.1101/2024.02.18.580839 — genetics — Posted on 2024-02-21

1502 Genetic Modulation of Protein Expression in Rat Brain

li, L.; Wu, Z.; Guarracino, A.; Villani, F.; Kong, D.; Mancieri, A.; Zhang, A.; Saba, L. M.; Chen, H.; Brozka, H.; Vales, K.; Senko, A. N.; Kempermann, G.; Stuchlik, A.; Pravenec, M.; Prins, P.; Peng, J.; Wang, X.

10.1101/2024.02.17.580840 — genetics — Posted on 2024-02-21

1503 Chromosomal inversions harbour excess mutational load in the coral, Acropora kenti, on the Great Barrier Reef

Zhang, J.; Schneller, N. M.; Field, M. A.; Chan, C. X.; Miller, D. J.; Strugnell, J. M.; Riginos, C.; Bay, L.; Cooke, I. R.

10.1101/2024.02.19.580031 — evolutionary biology — Posted on 2024-02-21

1504 Resolving Paradoxes in Molecular Evolution: The Integrated WF-Haldane (WFH) Model of Genetic Drift

Ruan, Y.; Wang, X.; Hou, M.; Diao, W.; Xu, S.; Wen, H.; Wu, C.-I.

10.1101/2024.02.19.581083 — evolutionary biology — Posted on 2024-02-21

1505 Eco-evolutionary dynamics for finite populations and the noise-induced reversal of selection

Bhat, A. S.; Guttal, V.

10.1101/2024.02.19.580940 — evolutionary biology — Posted on 2024-02-21

1506 Adaptive Mate Selection in Saccharomyces cerevisiae Revealed Through a High-Throughput Mating Assay

Struass, S. K.; Liti, G.; Dahan, O.; Pilpel, Y. T.

10.1101/2024.02.18.580925 — evolutionary biology — Posted on 2024-02-21

1507 The genetic consequences of historic climate change on the contemporary population structure of a widespread temperate North American songbird

Cloutier, A.; Chan, D. T. C.; Poon, E. S. K.; Sin, S. Y. W.

10.1101/2024.02.18.580918 — evolutionary biology — Posted on 2024-02-21

1508 MATEdb2, a collection of high-quality metazoan proteomes across the Animal Tree of Life to speed up phylogenomic studies

Martinez-Redondo, G. I.; Vargas-Chavez, C.; Eleftheriadi, K.; Benitez-Alvarez, L.; Vazquez-Valls, M.; Fernandez, R.

10.1101/2024.02.21.581367 — evolutionary biology — Posted on 2024-02-21

1509 Evaluation of a nanopore sequencing strategy on bacterial communities from marine sediments

Lemoinne, A.; Dirberg, G.; Georges, M.; Robinet, T.

10.1101/2023.06.06.541006 — molecular biology — Posted on 2024-02-21

1510 The satiety hormone cholecystokinin gates reproduction in fish by controlling gonadotropin secretion

Hollander cohen, L.; Cohen, O.; Shulman, M.; Aiznkot, T.; Fontanaud, P.; Revah, O.; Mollard, P.; Golan, M.; Levavi Sivan, B.

10.1101/2023.06.18.545454 — neuroscience — Posted on 2024-02-21

1511 When Age Tips the Balance: a Dual Mechanism Affecting Hemispheric Specialization for Language

Roger, E.; Labache, L.; Hamlin, N.; Kruse, J.; Baciu, M.; Doucet, G. E.

10.1101/2023.12.04.569978 — neuroscience — Posted on 2024-02-21

1512 Prior Knowledge Biases the Visual Memory of Body Postures

Han, Q.; Gandolfo, M.; Peelen, M. V.

10.1101/2022.12.01.518647 — neuroscience — Posted on 2024-02-21

1513 Development of a whole-cell biosensor for ethylene oxide and ethylene

Moratti, C. F.; Yang, S. N. N.; Scott, C.; Coleman, N. V.

10.1101/2024.02.19.581074 — synthetic biology — Posted on 2024-02-21

1514 Pectin methylesterase activity is required for RALF1 peptide signalling output

Roessling, A.-K.; Dunser, K.; Liu, C.; Lauw, S.; Rodriguez- Franco, M.; Kalmbach, L.; Barbez, E.; Kleine-Vehn, J.

10.1101/2023.08.18.553913 — plant biology — Posted on 2024-02-21

1515 ModiFinder: Tandem Mass Spectral Alignment Enables Structural Modification Site Localization

Shahneh, M. R. Z.; Strobel, M.; Vitale, G. A.; Geibel, C.; El Abiead, Y.; Garg, N.; Aron, A. T.; Phelan, V. V.; Petras, D.; Wang, M.

10.1101/2024.02.17.580849 — bioinformatics — Posted on 2024-02-21

1516 Interpretable and explainable predictive machine learning models for data-driven protein engineering

Medina-Ortiz, D.; Khalifeh, A.; Anvari-Kazemabad, H.; D. Davari, M.

10.1101/2024.02.18.580860 — bioinformatics — Posted on 2024-02-21

1517 Comparative Multi-omic Mapping of Human Pancreatic Islet Endoplasmic Reticulum and Cytokine Stress Responses Provides Insights into Type 2 Diabetes Genetics

Sokolowski, E. K.; Kursawe, R.; Selvam, V.; Bhuiyan, R. M.; Thibodeau, A.; Zhao, C.; Spracklen, C. N.; Ucar, D.; Stitzel, M. L.

10.1101/2024.02.17.580646 — genomics — Posted on 2024-02-21

1518 An explanation for the neighbour repulsion phenomenon in Patterson's f-statistics

Atag, G.; Somel, M.

10.1101/2024.02.17.580509 — genetics — Posted on 2024-02-21

1519 Selection on sporulation strategies in a metapopulation can lead to coexistence

proulx, S. R.; Sakal, T. R.; Thomasson, K. M.

10.1101/2024.02.17.580810 — evolutionary biology — Posted on 2024-02-21

1520 Mycorrhizal and endophytic fungi structure contrasting but interdependent assembly processes in forest below-ground symbiosis

Noguchi, M.; Toju, H.

10.1101/2024.02.17.580831 — ecology — Posted on 2024-02-21

1521 From Sight to Insight: A Multi-task Approach with the Visual Language Decoding Model

Huang, W.; Yang, P.; Tang, Y.; Qin, F.; Li, H.; Wu, D.; Ren, W.; Wang, S.; Zhao, Y.; Wang, J.; Liu, H.; Li, J.; Zhu, Y.; Zhou, B.; Sun, J.; Li, Q.; Cheng, K.; Yan, H.; Chen, H.

10.1101/2024.02.16.580578 — neuroscience — Posted on 2024-02-21

1522 Ligify: Automated genome mining for ligand-inducible transcription factors

d'Oelsnitz, S.; Ellington, A. D.; Ross, D.

10.1101/2024.02.20.581298 — synthetic biology — Posted on 2024-02-21

1523 WITHDRAWN: Identification and validation of ITS2-specific universal primers for DNA barcoding in plants.

Bhat, A. R.; Hegde, S.; Kammar, S. S.; Muthamma, M. B.; Mudgal, G.; Mohan, T. C.; R, C.

10.1101/2024.01.05.574284 — plant biology — Posted on 2024-02-21

1524 A candidate sex determination locus in amphibians, evolved by structural variation between X- and Y-chromosomes

Kuhl, H.; Tan, W.-H.; Klopp, C.; Kleiner, W.; Koyun, B.; Ciorpac, M.; Feron, R.; Knytl, M.; Kloas, W.; Schartl, M.; Winkler, C. W.; Stoeck, M.

10.1101/2023.10.20.563234 — genomics — Posted on 2024-02-21

1525 Sex-biased regulatory changes in the placenta of native highlanders contribute to adaptive fetal development

Yue, T.; Guo, Y.; Qi, X.; Zheng, W.; Zhang, H.; Wang, B.; Zhou, B.; Zeng, X.; NA, O.; He, Y.; Su, B.

10.1101/2023.05.24.542081 — evolutionary biology — Posted on 2024-02-21

1526 morphoHeart: a novel quantitative tool to perform integrated 3D morphometric analyses of heart and ECM morphology during embryonic development

Sanchez-Posada, J.; Noël, E. S.

10.1101/2024.02.19.580991 — developmental biology — Posted on 2024-02-21

1527 Epigenetic age estimation of wild mice using faecal samples

Hanski, E.; Joseph, S.; Raulo, A.; Wanelik, K.; O'Toole, A.; Knowles, S. C. L.; Little, T. J.

10.1101/2023.10.25.563913 — molecular biology — Posted on 2024-02-21

1528 Gene-Dose-Dependent Reduction Fshr Expression Improves Spatial Memory Deficits in Alzheimer's Mice

Korkmaz, F.; Sims, S.; Sen, F.; Sultana, F.; Laurencin, V.; Cullen, L.; Pallapati, A. R.; Liu, A.; Rojekar, S.; Pevnev, G.; Cheliadinova, U.; Vasilyeva, D.; Burganova, G.; Macdonald, A.; Saxena, M.; Goosens, K.; Rosen, C.; Barak, O.; Lizneva, D.; Gumerova, A.; Ye, K.; Ryu, V.; Yuen, T.; Frolinger, T.; Zaidi, M.

10.1101/2024.02.16.580761 — neuroscience — Posted on 2024-02-21

1529 Associations between regional blood-brain barrier disruption, aging, and Alzheimers disease biomarkers in cognitively normal older adults

Denkinger, M.; Baker, S.; Inglis, B.; Kobayashi, S.; Juarez, A.; Mason, S.; Jagust, W.

10.1101/2024.02.16.580788 — neuroscience — Posted on 2024-02-21

1530 Epigenetic repression of cFos supports sequential formation of distinct spatial memories

Franzelin, A.; Lamothe-Molina, P. J.; Gee, C. E.; Formozov, A.; Schreiter, E. R.; Morellini, F.; Oertner, T. G.

10.1101/2024.02.16.580703 — neuroscience — Posted on 2024-02-21

1531 Pharyngeal Mechanosensory Neurons Control Food Swallow in Drosophila melanogaster

Qin, J.; Yang, T.; Li, K.; Liu, T.; Zhang, W.

10.1101/2023.04.21.537850 — neuroscience — Posted on 2024-02-21

1532 Theoretical principles explain the structure of the insect head direction circuit

Aceituno, P. V.; Dall'Osto, D.; Pisokas, I.

10.1101/2023.07.05.547838 — neuroscience — Posted on 2024-02-21

1533 Mathematical Modeling of Impacts of Patient Differences on Renin-Angiotensin System and Applications to COVID-19 Lung Fibrosis Outcomes

Islam, M. A.; Ford Versypt, A. N.

10.1101/2022.11.06.515367 — systems biology — Posted on 2024-02-21

1534 Diverse transcriptome reprogramming trajectories underlie quantitative disease resistance at the species level

Delplace, F.; Khafif, M.; Raffaele, S.

10.1101/2024.02.15.580486 — plant biology — Posted on 2024-02-21

1535 Blocking Interleukin-1beta transiently limits left ventricular dilation and reduces cardiac lymphangiogenesis in a mouse pressure-overload model

Heron, C.; Lemarcis, T.; Bundalo, M.; Laguerre, O.; Valentin, C.; Valet, M.; Michel, J.-B.; Mulder, P.; Zernecke, A.; Tardif San Martin, V.; Brakenhielm, E.

10.1101/2023.04.01.535056 — physiology — Posted on 2024-02-21

1536 Blockade of TREM2 ameliorates pulmonary inflammation and fibrosis by modulating sphingolipid metabolism

Gu, X.; Kang, H.; Cao, S.; Tong, Z.; Song, N.

10.1101/2024.02.16.580779 — pharmacology and toxicology — Posted on 2024-02-21

1537 Releasable hydrogel microsphere-drug conjugates as generic prodrugs for long-acting intra-tumoral therapy

Henise, J.; Hangasky, J. A.; Charych, D.; Carreras, C. W.; Ashley, G. W.; Santi, D. V.

10.1101/2024.02.16.580368 — cancer biology — Posted on 2024-02-21

1538 Evidence for a transfer-to-trap mechanism of fluorophore concentration quenching in lipid bilayers

Meredith, S. A.; Kusunoki, Y.; Evans, S. D.; Morigaki, K.; Connell, S. D.; Adams, P. G.

10.1101/2024.02.16.580699 — biophysics — Posted on 2024-02-21

1539 Characterization of an amyloidogenic intermediate of transthyretin by NMR relaxation dispersion

Leach, B. I.; Ferguson, J. A.; Morgan, G. J.; Sun, X.; Kroon, G.; Oyen, D.; Dyson, J.; Wright, P.

10.1101/2024.02.16.580707 — biophysics — Posted on 2024-02-21

1540 Integrated multi-omics analyses reveal the pro-inflammatory and pro-fibrotic pulmonary macrophage subcluster in silicosis

Kang, H.; Gu, X.; Cao, S.; Tong, Z.; Song, N.

10.1101/2024.02.16.580775 — bioinformatics — Posted on 2024-02-21

1541 mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms

Barnabe, C.; Sempere, G.; Manzanilla, V.; Moo Millan, J.; Amblard-Rambert, A.; Waleckx, E.

10.1101/2024.02.08.579441 — bioinformatics — Posted on 2024-02-21

1542 ProHap enables proteomic database generation accounting for population diversity

Vasicek, J.; Kuznetsova, K. G.; Skiadopoulou, D.; Johansson, S.; Njolstad, P. R.; Bruckner, S.; Kall, L.; Vaudel, M.

10.1101/2023.12.24.572591 — bioinformatics — Posted on 2024-02-21

1543 A Multi-objective Simulation-Optimization Framework for the Design of a Compliant Gravity Balancing Orthosis

Chishty, H. A.; Sergi, F.

10.1101/2024.02.16.580745 — bioengineering — Posted on 2024-02-21

1544 Computer vision analysis of mother-infant interaction identified efficient pup retrieval in V1b vasopressin receptor knockout mice

Sajjaviriya, C.; Fujianti, F.; Azuma, M.; Tsuchiya, H.; Koshimizu, T.-a.

10.1101/2024.02.16.580409 — animal behavior and cognition — Posted on 2024-02-21

1545 First chromosome-level genome assembly of a ribbon worm from the Hoplonemertea clade, Emplectonema gracile, and its structural annotation

Valero-Gracia, A.; Roberts, N. G.; Yap-Chiongco, M.; Capucho, A. T.; Kocot, K. M.; Matschiner, M.; Struck, T. H.

10.1101/2024.02.16.580704 — genomics — Posted on 2024-02-21

1546 Screening and assessment of functional variants by regulatory features from epigenomic data in livestock species

Ma, R.; Kuang, R.; Zhang, J.; Xu, Y.; Han, Z.; Hu, M.; Wang, D.; Luan, Y.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Zhao, Y.

10.1101/2024.02.06.578787 — genomics — Posted on 2024-02-21

1547 Diploid genome assembly of the Malbec grapevine cultivar enables haplotype-aware analysis of transcriptomic differences underlying clonal phenotypic variation

Calderon, L.; Carbonell-Bejerano, P.; Munoz, C.; Bree, L.; Sola, C.; Bergamin, D.; Tulle, W.; Gomez-Talquenca, S.; Lanz, C.; Royo, C.; Ibanez, J.; Martinez-Zapater, J. M.; Weigel, D.; Lijavetzky, D.

10.1101/2023.11.30.569420 — genomics — Posted on 2024-02-21

1548 Dominant nonsense mutations in efemp1 alter vertebral and craniofacial characteristics in adult zebrafish

Gomez, A. E.; Alvarado, K.; Yase, R. A.; Hsu, Y.-H.; Hulleman, J. D.; Kwon, R. Y.

10.1101/2024.02.16.580611 — genetics — Posted on 2024-02-21

1549 Small-molecule-based regulation of gene expression in human astrocytes upon both positive and negative actuations of G-quadruplex control systems

Kumar, M. J. V.; Mitteaux, J.; Wang, Z.; Wheeler, E.; Tandon, N.; Jung, S. Y.; Hudson, R. H. E.; Monchaud, D.; Tsvetkov, A. S.

10.1101/2024.02.16.580621 — genetics — Posted on 2024-02-21

1550 Population model of epigenetic inheritance of acquired adaptation to changing environments

Osmanovic, D.; Rabin, Y.; Soen, Y.

10.1101/2024.02.16.580565 — evolutionary biology — Posted on 2024-02-21

1551 Functional trade-offs: exploring the temporal response of field margin plant communities to climate change and agricultural practices

Poinas, I.; Meynard, C. N.; Fried, G.

10.1101/2023.03.03.530956 — ecology — Posted on 2024-02-21

1552 Microtubule forces drive nuclear damage in LMNA cardiomyopathy

Amiad Pavlov, D.; Corredera, C. S.; Dehghany, M.; Heffler, J.; Shen, K. M.; Zuela-Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.

10.1101/2024.02.10.579774 — cell biology — Posted on 2024-02-21

1553 Revisiting the high-dimensional geometry of population responses in visual cortex

Pospisil, D. A.; Pillow, J. W.

10.1101/2024.02.16.580726 — neuroscience — Posted on 2024-02-21

1554 Longitudinal study of neurochemical, volumetric and behavioral changes in Q140 & BACHD mouse models of Huntingtons disease

Zacharoff, L.; Tkac, I.; Shapiro, A.; Henry, P.-G.; Dubinsky, J. M.

10.1101/2024.02.16.580735 — neuroscience — Posted on 2024-02-21

1555 In vivo timelapse imaging and analysis of Golgi satellite organelle distribution and movement in the neural progenitor cells of the brain

Arellano, L. D.; Bestman, J. E.

10.1101/2024.02.16.580740 — neuroscience — Posted on 2024-02-21

1556 When most fMRI connectivity cannot be detected: insights from time course reliability

Koten, J. W.; Manner, H.; Pernet, C.; Schüppen, A.; Szücs, D.; Wood, G.; Ioannidis, J.

10.1101/2024.02.16.580783 — neuroscience — Posted on 2024-02-21

1557 DDHD2 provides a critical flux of saturated fatty acids to support neuronal energy demands

Saber, S. H.; Yak, N.; Yong, X. L. H.; Binder, T.; Lu, S.; Koludarova, L.; Purushothaman, R.; Er, S.; Hlushchuk, I.; Gaudin, A.; Nyman, T.; Harmer, J.; Talbo, G. H.; Airavaara, M.; Battersby, B.; van Waardenberg, A. J.; Anggono, V.; Balistreri, G.; Joensuu, M.

10.1101/2023.12.31.573799 — neuroscience — Posted on 2024-02-21

1558 Root Expansion Microscopy (ROOT-ExM): A streamlined super resolution method for plants

GRISON, M. S.; Maucort, G.; Dumazel, A.; Champelovier, D.; BOUTTE, Y.; Fernandez-Monreal, M.; Bayer, E.

10.1101/2024.02.21.581184 — plant biology — Posted on 2024-02-21

1559 Effects of foam rolling intervention on lactate clearance and cognitive function after high-intensity exercise with incremental load

Kasahara, K.; Oneyama, K.; Ito, T.; Nakamura, M.; Ochi, G.

10.1101/2024.02.16.580741 — physiology — Posted on 2024-02-21

1560 Interplay between Mg2+ and Ca2+ at multiple sites of the ryanodine receptor

Samso, M.; Nayak, A. R.; Rangubpit, W.; Will, A. H.; Hu, Y.; Castro-Hartmann, P.; Lobo, J. J.; Dryden, K.; Lamb, G. D.; Sompornpisut, P.

10.1101/2024.02.16.580716 — biophysics — Posted on 2024-02-21

1561 Elevated prevalence of the global panzootic chytrid strain in 1 Ecuadorian anurans of the Amazonian lowlands

Smart, U.; McCracken, S. F.; Brunner, R. M.; Rivera, C.; Rodriguez, D.

10.1101/2024.02.16.580711 — evolutionary biology — Posted on 2024-02-21

1562 Varying selection pressure for a Na+ sensing site in epithelial Na+ channel subunits reflect divergent roles in Na+ homeostasis

Wang, X.-P.; Srinivasan, P.; El Hamdaoui, M.; Grytz, R.; Kashlan, O.

10.1101/2024.02.16.580691 — evolutionary biology — Posted on 2024-02-21

1563 The Representation of Decision Variables in Orbitofrontal Cortex is Longitudinally Stable

Zhang, M.; Livi, A.; Carter, M.; Schoknecht, H.; Burkhalter, A.; Holy, T. E.; Padoa-Schioppa, C.

10.1101/2024.02.16.580715 — neuroscience — Posted on 2024-02-21

1564 AIBP controls amyloid beta induced TLR4 inflammarafts and mitochondrial dysfunction in microglia

Kim, Y. S.; CHOI, S.-H.; Kim, K.-Y.; Navia Pelaez, J. M.; Perkins, G. A.; Choi, S.; Miller, N. N.; Kim, J.; Ju, W.; Rissman, R. A.; Ellisman, M. H.; Miller, Y. I.

10.1101/2024.02.16.580751 — neuroscience — Posted on 2024-02-21

1565 Human spinal cord activation during filling and emptying of the bladder

Agyeman, K. A.; Lee, D. J.; Abedi, A.; Sakellaridi, S.; Kreydin, E.; Russin, J.; Lo, J. T.; Wu, K.; Choi, W.; Edgerton, R. V.; Liu, C.; Christopoulos, V. N.

10.1101/2024.02.16.580736 — neuroscience — Posted on 2024-02-21

1566 SCN gene expression plasticity in response to photoperiod

Cox, O. H.; Giannoni-Guzman, M. A.; Cartailler, J.-P.; Cottam, M. A.; McMahon, D. G.

10.1101/2024.02.16.580759 — neuroscience — Posted on 2024-02-21

1567 Super-resolution expansion microscopy in plant roots

Gallei, M.; Truckenbrodt, S.; Kreuzinger, C.; Inumella, S.; Vistunou, V.; Sommer, C.; Tavakoli, M. R.; Agudelo-Duenas, N.; Vorlaufer, J.; Jahr, W.; Randuch, M.; Johnson, A.; Benkova, E.; Friml, J.; Danzl, J. G.

10.1101/2024.02.21.581330 — plant biology — Posted on 2024-02-21

1568 Signaling and transcriptional dynamics underlying early adaptation to oncogenic BRAF inhibition

Flower, C. T.; Liu, C.; Chuang, H.-Y.; Ye, X.; Cheng, H.; Heath, J. R.; Wei, W.; White, F. M.

10.1101/2024.02.19.581004 — systems biology — Posted on 2024-02-21

1569 Towards Effective CAIX-targeted Radionuclide and Checkpoint Inhibition Combination Therapy for Advanced Clear Cell Renal Cell Carcinoma

Kleinendorst, S. C.; Oosterwijk, E.; Molkenboer-Kuenen, J.; Frielink, C.; Franssen, G.; Boreel, D. F.; Tamborino, G.; Gloudemans, M.; Hendrikx, M.; Kroon, D.; Hillen, J.; Bussink, J.; Muselaers, S.; Mulders, P.; Konijnenberg, M. W.; Wheatcroft, M. P.; Twumasi-Boateng, K.; Heskamp, S.

10.1101/2024.02.16.580614 — cancer biology — Posted on 2024-02-21

1570 Perivascular cells function as mechano-structural sensors of vascular capillaries

Franca, C. M.; Lima Verde, M. E.; Silva-Sousa, A. C.; Mansoorifar, A.; Athirasala, A.; Subbiah, R.; Tahayeri, A.; Sousa, M.; Fraga, M. A.; Visalakshan, R.; Doe, A.; Beadle, K.; Finley, M.; Dimitriadis, E.; Bays, J.; Uroz, M. M.; Yamada, K. M.; Chen, C. S.; Bertassoni, L. E.

10.1101/2024.02.16.580564 — bioengineering — Posted on 2024-02-21

1571 Oleic acid triggers CD4+ T cells to be metabolically rewired and poised to differentiate into proinflammatory T cell subsets upon activation

Reilly, N. A.; Sonnet, F.; Dekkers, K. F.; Kwekkeboom, J. C.; Sinke, L.; Hilt, S.; Suleiman, H. M.; Hoeksema, M. A.; Mei, H.; van Zwet, E. W.; Everts, B.; Ioan-Facsinay, A.; Jukema, J. W.; Heijmans, B. T.

10.1101/2024.02.16.580665 — genomics — Posted on 2024-02-21

1572 The genome of Przewalski's horse (Equus ferus przewalskii)

Flack, N.; Hughes, L.; Cassens, J.; Enriquez, M.; Gebeyehu, S.; Alshagawi, M.; Hatfield, J.; Kauffman, A.; Brown, B.; Klaeui, C.; Malbrouk, I. F.; Walls, C.; Yeater, T.; Rivas, A.; Faulk, C.

10.1101/2024.02.20.581252 — genomics — Posted on 2024-02-21

1573 An ability to respond begins with inner alignment: How phase synchronisation effects transitions to higher levels of agency

Tissot, T.; Levin, M.; Buckley, C. L.; Watson, R. A.

10.1101/2024.02.16.580248 — evolutionary biology — Posted on 2024-02-21

1574 Impact of a national tsetse control programme to eliminate Gambian sleeping sickness in Uganda: a spatio-temporal modelling study.

Longbottom, J.; Esterhuizen, J.; Hope, A.; Lehane, M. J.; Mangwiro, C. T.; Mugenyi, A.; Dunkley, S.; Selby, R.; Tirados, I.; Torr, S. J.; Stanton, M. C.

10.1101/2024.02.16.580671 — ecology — Posted on 2024-02-21

1575 Schwann cells have a limited window of time in which to initiate myelination program during early migration in vivo

El Hage, O.; Mikdache, A.; Boueid, M. J.; Degerny, C.; Tawk, M.

10.1101/2024.02.19.580938 — developmental biology — Posted on 2024-02-21

1576 De novo lipid synthesis and polarized prenylation drives cell invasion through basement membrane

Park, K.; Garde, A.; Thendral, S. B.; Soh, A. W. J.; Chi, Q.; Sherwood, D. R.

10.1101/2024.02.19.581070 — cell biology — Posted on 2024-02-21

1577 Dnmt3a mutations limit normal and autoreactive Tfh differentiation

Shen, Y.; Li, Z.; Boddul, S. V.; Kasza, Z.; Espinosa, A.; Klareskog, L.; Wermeling, F.

10.1101/2024.02.16.580463 — immunology — Posted on 2024-02-21

1578 An extremely fast neural mechanism to detect emotional visual stimuli: A two-experiment study

Carretie, L.; Fernandez-Folgueiras, U.; Kessel, D.; Alba, G.; Estrella, V.-Z.; Tapia, M.; Alvarez, F.

10.1101/2024.02.16.580636 — neuroscience — Posted on 2024-02-21

1579 Unveiling the genes and pathways that are dysregulated in dopaminergic neurons during both familial and sporadic Parkinson's disease.

Padhan, P. K.; VERMA, S.

10.1101/2024.02.19.580936 — neuroscience — Posted on 2024-02-21

1580 Neural codes track prior events in a narrative and predict subsequent memory for details

Collin, S. H. P.; Kempner, R. P.; Srivatsan, S.; Norman, K. A.

10.1101/2024.02.13.580092 — neuroscience — Posted on 2024-02-21

1581 Multi-orientation U-Net for Super-Resolution of Ultra-Low-Field Paediatric MRI

Baljer, L.; Zhang, Y.; Bourke, N. J.; Donald, K. A.; Bradford, L. E.; Ringshaw, J. E.; Williams, S. R.; Deoni, S. C.; Williams, S. C.; Khula SA Study Team, ; Vasa, F.; Moran, R. J.

10.1101/2024.02.16.580639 — neuroscience — Posted on 2024-02-21

1582 Polygenic risk for depression and resting state functional connectivity of subgenual anterior cingulate cortex in young adults

Chen, Y.; Li, H.-T.; Luo, X.; Li, G.; Ide, J. S.; Li, C.-S. R.

10.1101/2024.02.18.580883 — neuroscience — Posted on 2024-02-21

1583 Apnoea suppresses brain activity in infants

Zandvoort, C. S.; Dereymaeker, A.; Baxter, L.; Jansen, K.; Naulaers, G.; de Vos, M.; Hartley, C.

10.1101/2024.02.16.580547 — neuroscience — Posted on 2024-02-21

1584 Selective deletion of interleukin-1 alpha in microglia regulates neuronal activity and neurorepair processes after experimental ischemic stroke.

Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.

10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-02-21

1585 Circadian clocks in human cerebral organoids

Rzechorzek, N. M.; Sutcliffe, M. A.; Mihut, A.; Baranes, K.; Karam, N.; Lloyd-Davies Sanchez, D.; Peak-Chew, S. Y.; Zeng, A.; Poulin, N.; Seinkmane, E.; Karim, K.; Proctor, C. M.; Kotter, M.; Lancaster, M. A.; Beale, A. D.

10.1101/2024.02.20.580978 — neuroscience — Posted on 2024-02-21

1586 An axonal brake on striatal dopamine output by cholinergic interneurons

Zhang, Y.-F.; Luan, P.; Qiao, Q.; He, Y.; Zatka-Haas, P.; Zhang, G.; Lin, M.; Lak, A.; Jing, M.; Mann, E. O.; Cragg, S.

10.1101/2024.02.17.580796 — neuroscience — Posted on 2024-02-21

1587 Neuronal-class specific molecular cues drive differential myelination in the neocortex

Jokhi, V.; Dominguez-Iturza, N.; Kim, K.; Shetty, A. S.; Yuan, W.; Di Bella, D.; Abbate, C.; Oyler-Castrillo, P.; Jin, X.; Simmons, S.; Levin, J. Z.; Brown, J. R.; Arlotta, P.

10.1101/2024.02.20.581268 — neuroscience — Posted on 2024-02-21

1588 The Topology of Representational Geometry

Brown, S.; Farivar, R.

10.1101/2024.02.16.579506 — neuroscience — Posted on 2024-02-21

1589 Ndufs4 knockout induces transcriptomic signatures of Alzheimer's Diseases that are partially reversed by mitochondrial complex I inhibitor

Gao, H.; Jensen, K.; Nesbit, J.; Ostroot, M.; Baloni, P.; Funk, C. C.; Trushina, E.

10.1101/2024.02.20.581247 — neuroscience — Posted on 2024-02-21

1590 An interim exploratory biomarker analysis of a Phase 2 clinical trial to assess the impact of CT1812 in Alzheimers disease

Lizama, B. N.; North, H. A.; Pandey, K.; Williams, C.; Duong, D.; Cho, E.; Di Caro, V.; Ping, L.; Blennow, K.; Zetterberg, H.; Lah, J. J.; Levey, A. I.; Grundman, M.; Caggiano, A. O.; Seyfried, N. T.; Hamby, M. E.

10.1101/2024.02.16.578765 — neuroscience — Posted on 2024-02-21

1591 Chromatin regulator Kdm6b is required for the establishment and maintenance of neural stem cells in mouse hippocampus

Gil, E.; Hong, S. J.; Wu, D.; Park, D. H.; Delgado, R. N.; Malatesta, M.; Ahanger, S. H.; Lin, K.; Villeda, S.; Lim, D.

10.1101/2024.02.20.581302 — neuroscience — Posted on 2024-02-21

1592 Wider spread of excitatory neuron influence in association cortex than sensory cortex

Khoury, C. F.; Ferrone, M.; Runyan, C. A.

10.1101/2024.02.20.581200 — neuroscience — Posted on 2024-02-21

1593 2-D Neural Geometry Underpins Hierarchical Organization of Sequence in Human Working Memory

Fan, Y.; Wang, M.; Ding, N.; Luo, H.

10.1101/2024.02.20.581307 — neuroscience — Posted on 2024-02-21

1594 Opposing roles of physiological and pathological amyloid-β on synapses in live human brain slice cultures

McGeachan, R. I.; Meftah, S.; Taylor, L. W.; Catterson, J. H.; Negro, D.; Tulloch, J.; Rose, J. L.; Gobbo, F.; Liaquat, I.; Spires-Jones, T. L.; Booker, S. A.; Brennan, P. M.; Durrant, C. S.

10.1101/2024.02.16.580676 — neuroscience — Posted on 2024-02-21

1595 A deep learning-based toolkit for 3D nuclei segmentation and quantitative analysis in cellular and tissue context

Vijayan, A.; Mody, T. A.; Yu, Q.; Wolny, A.; Cerrone, L.; Strauss, S.; Tsiantis, M.; Smith, R. S.; Hamprecht, F.; Kreshuk, A.; Schneitz, K.

10.1101/2024.02.19.580954 — plant biology — Posted on 2024-02-21

1596 Efficient targeting of heart lesions with cardiac myofibroblasts: Combined gene and cell therapy enhanced by magnetic steering

Schiffer, M.; Wagner, K.; Carls, E.; Nicke, J.; Hesse, M.; Fratila, R.; Hildebrand, S.; Pfeifer, A.; Eberbeck, D.; Malek Mohammadi, M.; de la Fuente, J. M.; Fleischmann, B. K.; Roell, W.

10.1101/2024.02.16.580672 — physiology — Posted on 2024-02-21

1597 Label-free phenotyping of human microvessel networks

Rappez, L.; Akinbote, A.; Cherubini, M.; Uhlmann, V.; Haase, K.

10.1101/2024.02.20.581133 — bioengineering — Posted on 2024-02-21

1598 Modeling recent positive selection in Americans of European ancestry

Temple, S. D.; Waples, R. D.; Browning, S. R.

10.1101/2023.11.13.566947 — genetics — Posted on 2024-02-20

1599 Simple prerequisite of presequence for mitochondrial protein import in the unicellular red alga Cyanidioschyzon merolae

Hirata, R.; Mogi, Y.; Takahashi, K.; Nozaki, H.; Higashiyama, T.; Yoshida, Y.

10.1101/2024.02.19.581091 — cell biology — Posted on 2024-02-21

1600 The sperm hook in house mice: a functional adaptation for migration and self-organised behaviour

Ryu, H.; Nam, K.; Lee, B. E.; Jeong, Y.; Lee, S.; Kim, J.; Hyun, Y.-M.; Kim, J.-I.; Park, J.-H.

10.1101/2024.02.19.581047 — cell biology — Posted on 2024-02-21

1601 In situ observation and range extension of the first discovered monoplacophoran Neopilina galatheae

Chen, C.

10.1101/2023.11.08.566290 — zoology — Posted on 2024-02-20

1602 Profiling Glioma Stem Cell Dynamics via 3D-based Cell Cycle Reporter Assays

Lubanska, D.; Roye-Azar, A.; Alrashed, S.; Cieslukowski, A.; Soliman, M.; deCarvalho, A. C.; Shamisa, A.; Kulkarni, S.; Porter, L.

10.1101/2024.02.16.580653 — cancer biology — Posted on 2024-02-20

1603 HOCMO: A Tensor-based Higher-Order Correlation Model to Deconvolute Epigenetic Microenvironment in Breast Cancer

Lu, C.; Sherpa, R.; Klindziuk, L.; Kriel, S.; Mollah, S.

10.1101/2020.12.01.406249 — cancer biology — Posted on 2024-02-20

1604 Mapping the Single-cell Differentiation Landscape of Osteosarcoma

Truong, D. D.; Weistuch, C.; Murgas, K. A.; Admane, P.; King, B. L.; Chauviere Lee, J.; Lamhamedi-Cherradi, S.-E.; Swaminathan, J.; Daw, N. C.; Gordon, N.; Gopalakrishnan, V.; Gorlick, R. G.; Somaiah, N.; Deasy, J. O.; Mikos, A. G.; Tannenbaum, A.; Ludwig, J.

10.1101/2023.09.13.555156 — cancer biology — Posted on 2024-02-20

1605 An atlas of epithelial cell states and plasticity in lung adenocarcinoma

Han, G.; Sinjab, A.; Rahal, Z.; Lynch, A. M.; Treekitkarnmongkol, W.; Liu, Y.; Serrano, A. G.; Feng, J.; Liang, K.; Khan, K.; Lu, W.; Hernandez, S.; Liu, Y.; Cao, X.; Dai, E.; Pei, G.; Hu, J.; Abaya, C.; Gomez-Bolanoz, L. I.; Peng, F.; Chen, M.; Parra, E. R.; Cascone, T.; Sepesi, B.; Moghaddam, S. J.; Scheet, P.; Negrano, M. V.; Heymach, J. V.; Li, M.; Dubinett, S. M.; Stevenson, C. S.; Spira, A. E.; Fujimoto, J.; Solis, L. M.; Wistuba, I. I.; Chen, J.; Wang, L.; Kadara, H.

10.1101/2022.05.13.491635 — cancer biology — Posted on 2024-02-20

1606 Large-pore connexin hemichannels function as molecule transporters independently of ion conduction

Gaete, P. S.; Kumar, D.; Fernandez, C. I.; Valdez-Capuccino, J. M.; Bhatt, A.; Jiang, W.; Lin, Y.; Liu, Y.; Harris, A. L.; Luo, Y. L.; Contreras, J. E.

10.1101/2024.02.20.581300 — biophysics — Posted on 2024-02-20

1607 Focused small field of view magnetic particle imaging for the detection and quantification of tumour associated macrophages

Fernando, N.; Gevaert, J. J.; Konkle, J.; Goodwill, P.; Foster, P. J.

10.1101/2023.06.22.545970 — biophysics — Posted on 2024-02-20

1608 Discovery of regulatory motifs associated with human insulator sites reveals the role of directional bias in insulator function

Osato, N.; Hamada, M.

10.1101/2024.01.20.573595 — bioinformatics — Posted on 2024-02-20

1609 Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species

Chapuis, E.; Jarne, P.; David, P.

10.1101/2023.10.25.563987 — evolutionary biology — Posted on 2024-02-20

1610 RNA dicing regulates the expression of an oncogenic JAK1 isoform

Malka, Y.; van der Kammen, R.; Ju, S.; Alkan, F.; Lee, C.; Faller, W. J.

10.1101/2024.02.20.581186 — molecular biology — Posted on 2024-02-20

1611 Dynamical models reveal anatomically reliable attractor landscapes embedded in resting state brain networks

Chen, R.; Singh, M. F.; Braver, T. S.; Ching, S.

10.1101/2024.01.15.575745 — neuroscience — Posted on 2024-02-20

1612 Reinforcement learning during locomotion

Wood, J. M.; Kim, H. E.; Morton, S. M.

10.1101/2023.09.13.557581 — neuroscience — Posted on 2024-02-20

1613 Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells

Sun, Q.; Yu, L.; Donnelly, S. C.; Fradin, C.; Thompson, R. T.; Prato, F. S.; Goldhawk, D. E.

10.1101/2023.12.19.572379 — synthetic biology — Posted on 2024-02-20

1614 Subunit Communication within Dimeric SF1 DNA Helicases

Nguyen, B.; Hsieh, J.; Fischer, C. J.; Lohman, T. M.

10.1101/2024.02.20.581227 — biochemistry — Posted on 2024-02-20

1615 Beyond the Active Site: The addition of a remote loop reveals a new complex biological function for chitinase enzymes.

Kozome, D.; Sljoka, A.; Laurino, P.

10.1101/2023.02.27.530148 — biochemistry — Posted on 2024-02-20

1616 50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences

Kerdoncuff, E.; Skov, L.; Patterson, N.; Zhao, W.; Lueng, Y. Y.; Schellenberg, G. D.; Smith, J. A.; Dey, S.; Ganna, A.; Dey, A.; Kardia, S. L. R.; Lee, J.; Moorjani, P.

10.1101/2024.02.15.580575 — evolutionary biology — Posted on 2024-02-20

1617 Rapid Human Oogonia-like Cell Specification via Combinatorial TF-Directed Differentiation

Smela, M. P.; Kramme, C.; Fortuna, P. R.; Wolf, B.; Kavirayuni, V. S.; Adams, J. L.; Ma, C.; Velychko, S.; Widocki, U.; Goel, S.; Chen, T.; Vincoff, S.; Dong, E.; Kohman, R. E.; Kobayashi, M.; Shioda, T.; Church, G. M.; Chatterjee, P.

10.1101/2022.07.11.499564 — developmental biology — Posted on 2024-02-20

1618 Deciphering the genetic interactions between Pou4f3, Gfi1 and Rbm24 in maintaining cochlear hair cell survival

Wang, G.; Gu, Y.; Liu, Z.

10.1101/2023.06.22.546097 — developmental biology — Posted on 2024-02-20

1619 Live-cell fluorescence imaging and optogenetic control of PKA kinase activity in fission yeast Schizosaccharomyces pombe.

Sakai, K.; Aoki, K.; Goto, Y.

10.1101/2024.01.14.575615 — cell biology — Posted on 2024-02-20

1620 Translational control of MPS1 links protein synthesis with the initiation of cell division and spindle pole body duplication in Saccharomyces cerevisiae

Blank, H. M.; Alonso, A.; Fabritius, A. S.; Loog, M.; Winey, M.; Polymenis, M.

10.1101/2020.12.29.424704 — cell biology — Posted on 2024-02-20

1621 Re-coding of G protein-coupled receptor signaling enables emergent cellular behavior.

Dehkhoda, F.; Ringuet, M.; Whitfield, E. A.; Mutunduwe, K.; Nowell, C. J.; Misganaw, D.; Xu, Z.; Hossain, A. M.; Fothergill, L. J.; McDougall, S. J.; Furness, J. B.; Furness, S. G. B.

10.1101/2023.12.18.572241 — cell biology — Posted on 2024-02-20

1622 Opposing effects of pre-existing antibody and memory T cell help on the dynamics of recall germinal centers

Schiepers, A.; van 't Wout, M. F. L.; Hobbs, A.; Mesin, L.; Victora, G. D.

10.1101/2023.12.15.571936 — immunology — Posted on 2024-02-20

1623 Identifying regulators of associative learning using a protein-labelling approach in C. elegans

Rahmani, A.; McMillen, A.; Allen, E.; Ansaar, R.; Poljak, A.; Chew, Y. L.

10.1101/2024.02.19.580416 — neuroscience — Posted on 2024-02-20

1624 Resting EEG Periodic and Aperiodic Components Predict Cognitive Decline Over 10 Years

Finley, A. J.; Angus, D. J.; Knight, E. L.; van Reekum, C. M.; Lachman, M. E.; Davidson, R. J.; Schaefer, S. M.

10.1101/2023.07.17.549371 — neuroscience — Posted on 2024-02-20

1625 Multiple objects evoke fluctuating responses in several regions of the visual pathway

Schmehl, M. N.; Caruso, V. C.; Chen, Y.; Jun, N. Y.; Willett, S. M.; Mohl, J. T.; Ruff, D. A.; Cohen, M. R.; Ebihara, A.; Freiwald, W.; Tokdar, S. T.; Groh, J. M.

10.1101/2023.07.19.549668 — neuroscience — Posted on 2024-02-20

1626 Aberrant cortical activity, functional connectivity, and neural assembly architecture after photothrombotic stroke in mice

Bandet, M. V.; Winship, I. R.

10.1101/2023.06.13.544847 — neuroscience — Posted on 2024-02-20

1627 Secure Discovery of Genetic Relatives across Large-Scale and Distributed Genomic Datasets

Hong, M. M.-H.; Froelicher, D.; Magner, R.; Popic, V.; Berger, B.; Cho, H.

10.1101/2024.02.16.580613 — bioinformatics — Posted on 2024-02-20

1628 NeuroMDAVIS: Visualization of single-cell multi-omics data under deep learning framework

Maitra, C.; Seal, D. B.; Das, V.; De, R. K.

10.1101/2024.02.17.580541 — bioinformatics — Posted on 2024-02-20

1629 SpacerPlacer: Ancestral reconstruction of CRISPR arrays reveals the evolutionary dynamics of spacer deletions

Fehrenbach, A.; Mitrofanov, A.; Alkhnbashi, O. S.; Backofen, R.; Baumdicker, F.

10.1101/2024.02.20.581079 — bioinformatics — Posted on 2024-02-20

1630 LineageVAE: Reconstructing Historical Cell States and Transcriptomes toward Unobserved Progenitors

Majima, K.; Kojima, Y.; Minoura, K.; Abe, K.; Hirose, H.; Shimamura, T.

10.1101/2024.02.16.580598 — bioinformatics — Posted on 2024-02-20

1631 Multi-species numerical validation of an efficient algorithm for auditory brainstem response hearing threshold estimation

Petersen, E.; Shen, Y.

10.1101/2024.02.19.580836 — bioengineering — Posted on 2024-02-20

1632 RomX, a novel prokaryotic regulator, links the response receiver domain of RomR with GTP-bound MglA for establishing Myxococcus xanthus polarity

Chakraborty, S.; Gayathri, P.

10.1101/2024.02.20.581209 — biochemistry — Posted on 2024-02-20

1633 Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems

Denoeud, F.; Godfroy, O.; Cruaud, C.; Heesch, S.; Nehr, Z.; Tadrent, N.; Couloux, A.; Brillet-Gueguen, L.; Delage, L.; Dean, D.; Motomura, T.; Sussfeld, D.; Fan, X.; Mazeas, L.; Terrapon, N.; Barrera-Redondo, J.; Petroll, R.; Reynes, L.; Choi, S.-W.; Jo, J.; Uthanumallian, K.; Bogaert, K.; Duc, C.; Ratchinski, P.; Lipinska, A.; Noel, B.; Murphy, E. A.; Lohr, M.; Khatei, A.; Hamon-Giraud, P.; Vieira, C.; Akerfors, S. S.; Akita, S.; Avia, K.; Badis, Y.; Barbeyron, T.; Belcour, A.; Berrabah, W.; Blanquart, S.; Bouguerba, A.; Bringloe, T. T.; Cattolico, R. A.; Cormier, A.; Cruz de Carvalho, M. H.;

10.1101/2024.02.19.579948 — genomics — Posted on 2024-02-20

1634 Environmental factors and host sex influence the skin microbiome structure of Hong Kong newt (Paramesotriton hongkongensis) in a coldspot of chytridiomycosis in subtropical East Asia

Wan, B.; Chen, G.; Poon, E. S. K.; Fung, H. S.; Lau, A.; Sin, S. Y. W.

10.1101/2024.02.19.581002 — ecology — Posted on 2024-02-20

1635 Nuclear pore complexes undergo Nup221 exchange during blood stage asexual replication of Plasmodium parasites.

Blauwkamp, J. A.; Ambekar, S. V.; Hussain, T.; Mair, G. R.; Beck, J. R.; Absalon, S.

10.1101/2024.02.16.580747 — cell biology — Posted on 2024-02-20

1636 Reverse Engineering of Feedforward Cortical-Hippocampal Microcircuits for Modelling Neural Network Function and Dysfunction

Hanssen, K. S.; Winter-Hjelm, N.; Niethammer, S. N.; Kobro-Flatmoen, A.; Witter, M. P.; Sandvig, A.; Sandvig, I.

10.1101/2023.06.26.546556 — neuroscience — Posted on 2024-02-20

1637 Cross-species modeling and enhancement of cognitive control with striatal brain stimulation

10.1101/2024.02.16.580680 — neuroscience — Posted on 2024-02-20

1638 Binding of cortical functional modules by synchronous high frequency oscillations

Garrett, J. C.; Verzhbinsky, I. A.; Kaestner, E.; Carlson, C.; Doyle, W. K.; Devinsky, O.; Thesen, T.; Halgren, E.

10.1101/2023.05.20.541597 — neuroscience — Posted on 2024-02-20

1639 From Sight to Insight: A Multi-task Approach with the Visual Language Decoding Model

Huang, W.; Yang, P.; Tang, Y.; Qin, F.; Li, H.; Wu, D.; Ren, W.; Wang, S.; Zhao, Y.; Wang, J.; Liu, H.; Li, J.; Zhu, Y.; Zhou, B.; Sun, J.; Li, Q.; Cheng, K.; Yan, H.; Chen, H.

10.1101/2024.02.16.580578 — neuroscience — Posted on 2024-02-20

1640 A multiscale model of the mammalian liver circadian clock supports synchronization of autonomous oscillations by intercellular communication.

Marri, D. K.; Filipovic, D.; Kana, O. Z.; Zhang, Q.; Sluka, J.; Liu, S.; Bhattacharya, S.

10.1101/2024.02.15.580517 — systems biology — Posted on 2024-02-20

1641 ARTseq-FISH reveals position-dependent differences in gene expression of micropatterned mESCs

Hu, X.; van Sluijs, B.; Garcia Blay, O.; Stepanov, Y.; Rietrae, K.; Huck, W.; Hansen, M. M. K.

10.1101/2022.09.14.507902 — systems biology — Posted on 2024-02-20

1642 Chronic Stress effects on Immune-Neuroendocrine matrix in Coturnix japonica, analyses from an ontogenetic perspective

Marozzi, A.; Correa, S. G.; Palme, R.; Cantarelli, V. I.; Ponzio, M. F.; Marin, R. H.; Nazar, F. N.

10.1101/2024.01.24.577005 — physiology — Posted on 2024-02-20

1643 Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: Primary and secondary gene responses with links to disease progression

Sonkar, R.; Ma, H.; Waxman, D. J.

10.1101/2024.02.16.580717 — pharmacology and toxicology — Posted on 2024-02-20

1644 Secondary structure determines electron transport in peptides

Samajdar, R.; Meigooni, M.; Yang, H.; Li, J.; Liu, X.; Jackson, N. E.; Mosquera, M. A.; Tajkhorshid, E.; Schroeder, C. M.

10.1101/2024.02.18.578245 — biophysics — Posted on 2024-02-20

1645 Optimal antimicrobial response to a changing microbial background at a mucus interface

Bossa, G. V.; Bel, S.; Mugler, A.; Erez, A.

10.1101/2023.08.02.551591 — biophysics — Posted on 2024-02-20

1646 PyF2F: A robust and simplified fluorophore-to-fluorophore distance measurement tool for Protein interactions from Imaging Complexes after Translocation experiments

C. Hernandez, A.; Ortiz Giron, J. S.; Betancur ocampo, L. I.; Dojcilovic, R.; Picco, A.; Kaksonen, M.; Oliva, B.; Gallego, O.

10.1101/2024.02.16.580512 — bioinformatics — Posted on 2024-02-20

1647 Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics

Morin, A.; Chu, C.; Pavlidis, P.

10.1101/2024.02.15.580581 — bioinformatics — Posted on 2024-02-20

1648 An open-source MRI compatible frame for multimodal presurgical mapping in macaque and capuchin monkeys

Liang, L.; Zimmermann Rollin, I.; Alikaya, A.; Ho, J. C.; Santini, T.; Bostan, A. C.; Schwerdt, H. N.; Stauffer, W. R.; Ibrahim, T. S.; Pirondini, E.; Schaeffer, D.

10.1101/2024.02.17.580767 — bioengineering — Posted on 2024-02-20

1649 Information structure of heterogeneous criticality in fish school

Niizato, T.; Sakamoto, K.; Mototake, Y.-i.; Murakami, H.; Tomaru, T.

10.1101/2024.02.18.578833 — animal behavior and cognition — Posted on 2024-02-20

1650 Exploring the Genomic Landscape of the GP63 family in Trypanosoma cruzi: Evolutionary Dynamics and Functional Peculiarities

Berna, L.; Chiribao, M. L.; Pita, S.; Alvarez-Valin, F.; Parodi-Talice, A.

10.1101/2024.02.17.580826 — genomics — Posted on 2024-02-20

1651 PCNA unloading is crucial for the bypass of DNA lesions by homologous recombination

Arbel, M.; Liefshitz, B.; Katz, N.; Kuryachiy, M.; Kupiec, M.

10.1101/2024.02.18.580888 — genetics — Posted on 2024-02-20

1652 Retrotransposon-mediated variation of a chitin synthase gene confers insect resistance to Bacillus thuringiensis Vip3Aa toxin

Liu, Z.; Liao, C.; Zou, L.; Jin, M.; Shan, Y.; Quan, Y.; Yao, H.; Zhang, L.; Wang, P.; Liu, Z.; Wang, N.; Li, A.; Liu, K.; Heckel, D. G.; Wu, K.; Xiao, Y.

10.1101/2024.02.18.580648 — genetics — Posted on 2024-02-20

1653 Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera

Eynard, S. E.; Mondet, F.; Basso, B.; Bouchez, O. E.; Bulach, T.; Le Conte, Y.; Dainat, B.; Decourtye, A.; Genestout, L.; Guichard, M.; Guillaume, F.; Labarthe, E.; Locke, B.; Mahla, R.; de Miranda, J. R.; Neuditschko, M.; Phocas, F.; Poquet, Y.; Sann, C.; Serre, R.-F.; Tabet, K.; Vignal, A.; Servin, B.

10.1101/2024.02.16.580755 — genetics — Posted on 2024-02-20

1654 A tale of too many trees: a conundrum for phylogenetic regression

Adams, R.; Roa Lozano, J.; Duncan, M.; Green, J.; Assis, R.; DeGiorgio, M.

10.1101/2024.02.16.580530 — evolutionary biology — Posted on 2024-02-20

1655 Phylogeny predicts tolerance in aquatic animals for only a minority of chemicals

Coleman, A. L.; Edmands, S.

10.1101/2024.02.20.577278 — evolutionary biology — Posted on 2024-02-20

1656 High-resolution lineage tracking of within-host evolution and strain transmission in a human gut symbiont across ecological scales

Vasquez, K. S.; Wong, D. P. G. H.; Pedro, M. F.; Yu, F. B.; Jain, S.; Meng, X.; Higginbottom, S. K.; DeFelice, B. C.; Neff, N.; Bhatt, A. S.; Tropini, C.; Xavier, K. B.; Sonnenburg, J. L.; Good, B. H.; Huang, K. C.

10.1101/2024.02.17.580834 — evolutionary biology — Posted on 2024-02-20

1657 Predicting genetic biodiversity in salamanders using geographic, climatic, and life history traits

Parsons, D. J.; Green, A. E.; Carstens, B. C.; Pelletier, T. A.

10.1101/2024.02.16.580580 — evolutionary biology — Posted on 2024-02-20

1658 morphoHeart: a novel quantitative tool to perform integrated 3D morphometric analyses of heart and ECM morphology during embryonic development

Noël, E. S.; Sanchez-Posada, J.

10.1101/2024.02.19.580991 — developmental biology — Posted on 2024-02-20

1659 The evolutionary dynamics of alternative splicing during primate neuronal differentiation

Ritter, A.; Wallace, A.; Ronaghi, N.; Sanford, J.

10.1101/2024.02.20.581203 — molecular biology — Posted on 2024-02-20

1660 Regulated mRNA recruitment in dinoflagellates is reflected in hyper-variable mRNA spliced leaders and novel eIF4Es

Jones, G. D.; Williams, E. P.; Haq, S.; Bachvaroff, T. R.; Sanchez, M. B.; Place, A. R.; Jagus, R.

10.1101/2024.02.20.581179 — molecular biology — Posted on 2024-02-20

1661 Microbiome- and Host Inflammasome-Targeting Inhibitor Nanoliogmers are Therapeutic in Murine Colitis Model

Sharma, S.; Gilberto, V. S.; Levens, C. L.; Chatterjee, A.; Kuhn, K. A.; Nagpal, P.

10.1101/2024.02.20.581256 — molecular biology — Posted on 2024-02-20

1662 Unraveling the gut microbiota of Tibetan chickens: insights into highland adaptation and ecological advantages

Zeng, T.; Cao, Y.; Yin, J.; Feng, P.; TIAN, Y.; Sun, H.; GU, T.; Zong, Y.; Ma, X.; Zhao, Z.; Chen, L.; XU, W.; Han, W.; Lu, L.

10.1101/2024.02.19.581084 — microbiology — Posted on 2024-02-20

1663 Exposure assessment suggests some cytotoxic Bacillus cereus group genotypes can grow over 3 logs in HTST milk throughout the shelf life at temperature abuse conditions

Su, J.; Chandross-Cohen, T.; Qian, C.; Carroll, L. M.; Kimble, K.; Yount, M.; Wiedmann, M.; Kovac, J.

10.1101/2024.02.20.581219 — microbiology — Posted on 2024-02-20

1664 A difficult coexistence: resolving the iron-induced nitrification delay in groundwater filters

Corbera-Rubio, F.; Kruisdijk, E.; Malheiro, S.; Leblond, M.; Verschoor, L.; van Loosdrecht, M.; Laureni, M.; van Halem, D.

10.1101/2024.02.19.581000 — microbiology — Posted on 2024-02-20

1665 How muscle synergies fail to solve the muscle redundancy problem during human reaching

Korol, A. S.; Gritsenko, V.

10.1101/2024.02.12.579990 — neuroscience — Posted on 2024-02-20

1666 Directed evolution of a bacterial leucyl tRNA in mammalian cells for enhanced noncanonical amino acid mutagenesis

Huang, R. L.; Jewel, D.; Kelemen, R. E.; Pham, Q.; Wang, S.; Roy, S. J. S.; Huang, Z.; Levinson, S. D.; Sundaresh, B.; Miranda, S. E.; van Opijnen, T.; Chatterjee, A.

10.1101/2024.02.19.581038 — synthetic biology — Posted on 2024-02-20

1667 Optogenetic Regulation of EphA1 RTK Activation and Signaling

Wurz, A. I.; Zheng, K. S.; Hughes, R. M.

10.1101/2024.02.06.579139 — synthetic biology — Posted on 2024-02-20

1668 A Novel Support Vector Machine-Based One-Day, Single-Dose Prediction Model of Genotoxic Hepatocarcinogenicity in Rats

Gi, M.; Suzuki, S.; Kanki, M.; Yokohira, M.; Tsukamoto, T.; Fujioka, M.; Vachiraarunwong, A.; Qiu, G.; Guo, R.; Wanibuchi, H.

10.1101/2024.02.19.579908 — pharmacology and toxicology — Posted on 2024-02-20

1669 The Strongest Protein Binder is Surprisingly Labile

Fernandez-Calvo, A.; Reifs, A.; Saa, L.; Cortajarena, A. L.; De Sancho, D.; Perez-Jimenez, R.

10.1101/2024.02.18.580677 — biophysics — Posted on 2024-02-20

1670 Design and optimization of novel succinate dehydrogenase inhibitors against agricultural fungi based on Transformer model

Pian, C.; Zhang, Y.; Chai, J.; Li, L.; Zhao, W.; Zhang, L.; Chen, Y.; Xu, Z.; Yang, C.

10.1101/2024.02.20.581130 — biochemistry — Posted on 2024-02-20

1671 Transcriptional perturbation of LINE-1 elements reveals their cis-regulatory potential

Perez-Rico, Y. A.; Bousard, A.; Misikova, L. H.; Mulugeta, E.; de Almeida, S. F.; Muotri, A. R.; Heard, E.; Gendrel, A.-V.

10.1101/2024.02.20.581275 — genomics — Posted on 2024-02-20

1672 Cellular heterogeneity in the developing forebrain masks transcriptional outcomes and principles of Evf2 enhancer lncRNA-Dlx5/6UCE-gene guidance

Li, E.; Chakraborty, A.; Kohtz, S. J.; Cajigas, I.; Shiau, F.; Vassar, R.; Clark, B. S.; Kohtz, J. D.

10.1101/2024.02.20.581236 — molecular biology — Posted on 2024-02-20

1673 Retention of the full visual opsin repertoire in Australia's cryptozoic lizards

Ford, M. J. R.; Ludington, A. J.; Bradford, T.; Sanders, K. L.; Hutchinson, M. N.; Simoes, B. F.

10.1101/2024.02.19.581082 — molecular biology — Posted on 2024-02-20

1674 Fitness adaptations of Japanese encephalitis virus in pigs following vector-free serial passaging

Marti, A.; Nater, A.; Pego Magalhaes, J.; Almeida, L.; Lewandowska, M.; Liniger, M.; Ruggli, N.; Grau-Roma, L.; Alnaji, F.; Vignuzzi, M.; Garcia-Nicolas, O.; Summerfield, A.

10.1101/2024.02.20.581151 — microbiology — Posted on 2024-02-20

1675 Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics

Hussein, M.; Mahboob, M. B.; Tait, J. R.; Grace, J. L.; Montembault, V.; Fontaine, L.; Quinn, J. F.; Velkov, T.; Whittaker, M. R.; Landersdorfer, C. B.

10.1101/2024.02.19.581110 — microbiology — Posted on 2024-02-20

1676 Temporal dynamics of Candida albicans morphogenesis and gene expression reveals distinctions between in vitro and in vivo filamentation.

Wakade, R. S.; Wellington, M.; Krysan, D. J.

10.1101/2024.02.20.581211 — microbiology — Posted on 2024-02-20

1677 Characterisation and comparison of semen microbiota and sperm function in men with infertility, recurrent miscarriage, or proven fertility

Mowla, S.; Farahani, L.; Tharakan, T.; Davies, R.; Correia, G. D.; Lee, Y. S.; Kundu, S.; Khanjani, S.; Sindi, E.; Rai, R.; Regan, L.; Khalifa, D.; Henkel, R.; Minhas, S.; S. Dhillo, W.; Ben Nagi, J.; Bennett, P.; MacIntrye, D. A.; Jayasena, C. N.

10.1101/2024.02.18.580923 — microbiology — Posted on 2024-02-20

1678 Proteomic comparison of epidemic Australian Bordetella pertussis biofilm cells

Suyama, H.; Luu, L. D. W.; Zhong, L.; Raftery, M. J.; Lan, R.

10.1101/2024.02.19.581093 — microbiology — Posted on 2024-02-20

1679 A new model of endotracheal tube biofilm identifies combinations of matrix-degrading enzymes and antimicrobials able to eradicate biofilms of pathogens that cause ventilator-associated pneumonia

Walsh, D.; Parmenter, C.; Bakker, S. E.; Lithgow, T.; Traven, A.; Harrison, F.

10.1101/2024.02.20.581163 — microbiology — Posted on 2024-02-20

1680 Proteomic analysis of gut in Labeo rohita reveals ECM as Key Player in host's Response to Aeromonas hydrophila Infection

Nissa, M. U.; Pinto, N.; Ghosh, B.; Banerjee, A.; Singh, U.; Goswami, M.; Srivastava, S.

10.1101/2024.02.19.581092 — microbiology — Posted on 2024-02-20

1681 Nasal commensals reduce Staphylococcus aureus proliferation by restricting siderophore availability

Zhao, Y.; Bitzer, A.; Power, J. J.; Belikova, D.; Torres-Salazar, B.; Adolf, L. A.; Gerlach, D.; Krismer, B.; Heilbronner, S.

10.1101/2024.02.20.581135 — microbiology — Posted on 2024-02-20

1682 Pooled CRISPR interference screening identifies crucial transcription factors in gas-fermenting Clostridium ljungdahlii

Zhang, H.; Feng, H.; Xing, X.-H.; Zhang, C.; Gu, Y.

10.1101/2024.02.20.581120 — microbiology — Posted on 2024-02-20

1683 Birnaviral Hijacking of Endosomal Membranes

Zanetti, F. A.; Fernandez, I.; Baquero, E.; Guardado-Calvo, P.; Dubois, S.; Morel, E.; Alfonso, V.; Aguilera, M. O.; Celayes, E. E.; Polo, L. M.; Suhaiman, L.; Galassi, V. V.; Chiarpotti, M. V.; Allende, C.; Rodriguez, J. M.; Caston, J. R.; Lijavetzky, D.; Taboga, O.; Colombo, M. I.; Del Popolo, M. G.; Rey, F. A.; Delgui, L. R.

10.1101/2024.02.20.581221 — microbiology — Posted on 2024-02-20

1684 Characterization of the SARS-CoV-2 BA.5 Variants in H11-K18-hACE2 Hamsters

Dong, M.; Lin, H.; Pan, M.; Huang, M.; Liu, M.; Jiang, R.; Lai, Y.; Shi, A.; Yao, B.; Hu, B.; Shi, Z.; Zhang, A.; Gao, Y.; Zeng, W.; Li, J.

10.1101/2024.02.19.581112 — immunology — Posted on 2024-02-20

1685 Prior exposure to malaria decreases SARS-CoV-2 mediated mortality in K18-hACE2 mice without influencing viral load in lungs

Mawatwal, S.; Mohapatra, A.; Das, S.; Ray, A.; Mukherjee, R.; Syed, G. H.; Senapati, S.; Ravindran, B.

10.1101/2024.02.19.579434 — immunology — Posted on 2024-02-20

1686 Leading an urban invasion: risk-sensitive learning is a winning strategy

Breen, A. J.; Deffner, D.

10.1101/2023.03.19.533319 — animal behavior and cognition — Posted on 2024-02-20

1687 Predicting Antibody and ACE2 Affinity for SARS-CoV-2 BA.2.86 and JN.1 with In Silico Protein Modeling and Docking

Yasa, S. R.; Guirales-Medrano, S.; Jacob Machado, D.; Ford, C. T.; Janies, D.

10.1101/2023.11.22.568364 — bioinformatics — Posted on 2024-02-20

1688 Electrode sharpness and insertion speed reduce tissue damage near high-density penetrating arrays

McNamara, I. N.; Wellman, S. M.; Li, L.; Eles, J. R.; Savya, S.; Sohal, H.; Angle, M.; Kozai, T. D. Y.

10.1101/2023.11.22.568119 — bioengineering — Posted on 2024-02-20

1689 Full-length transcript sequencing traces the brain isoform diversity in house mouse natural populations

Zhang, W.; Guenther, A.; Gao, Y.; Ullrich, K. K.; Huettel, B.; Tautz, D.

10.1101/2024.01.03.573993 — genomics — Posted on 2024-02-20

1690 The Alk receptor tyrosine kinase regulates Sparkly, a novel activity regulating neuropeptide precursor in the Drosophila CNS.

Sukumar, S. K.; Antonydhason, V.; Molander, L.; Sandakly, J.; Kleit, M.; Umapathy, G.; Mendoza-Garcia, P.; Masudi, T.; Schlosser, A.; Nassel, D. R.; Wegener, C.; Shirinian, M.; Palmer, R.

10.1101/2023.06.02.543395 — developmental biology — Posted on 2024-02-20

1691 Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

Wang, F.; Liu, X.; Huang, F.; Zhou, Y.; Wang, X.; Song, Z.; Wang, S.; Wang, X.; Shi, D.; Ruan, G.; Ji, X.; Zhang, E.; Tan, Z.; Ye, Y.; Wang, C.; Zhu, J.; Wang, W.

10.1101/2023.06.02.543432 — microbiology — Posted on 2024-02-20

1692 A Genome-Wide Arrayed CRISPR Screen Reveals PLSCR1 as an Intrinsic Barrier to SARS-CoV-2 Entry

Le Pen, J.; Paniccia, G.; Bauer, M.; Hoffmann, H.- H.; Kinast, V.; Moncada-Velez, M.; Pinharanda, A.; Ricardo-Lax, I.; Stenzel, A. F.; Rosado-Olivieri, E. A.; Ashbrook, A. W.; Dinnon, K. H.; Doyle, W.; Freije, C.; Hong, S.-H.; Lee, D.; Lewy, T.; Luna, J. M.; Peace, A.; Schmidt, C.; Schneider, W. M.; Winkler, R.; Larson, C.; McGinn, T.; Menezes, M.-R.; Ramos-Espiritu, L.; Banerjee, P.; Poirier, J. T.; Sanchez-Rivera, F. J.; Zhang, Q.; Casanova, J.-L.; Carroll, T. S.; Glickman, J. F.; Michailidis, E.; Razooky, B.; MacDonald, M. R.; Rice, C. M.

10.1101/2024.02.16.580725 — immunology — Posted on 2024-02-20

1693 Visual Image Reconstructed Without Semantics fromHuman Brain Activity Using Linear Image Decodersand Nonlinear Noise Suppression

Li, Q.

10.1101/2023.09.23.559147 — neuroscience — Posted on 2024-02-20

1694 Cortical gene expression architecture links healthy neurodevelopment to the imaging, transcriptomics, and genetics of autism and schizophrenia

Dear, R.; Wagstyl, K.; Seidlitz, J.; Markello, R. D.; Arnatkeviciute, A.; Anderson, K. M.; Bethlehem, R. A. I.; Lifespan Brain Chart Consortium, ; Raznahan, A.; Bullmore, E. T.; Vertes, P.

10.1101/2022.10.05.510582 — neuroscience — Posted on 2024-02-20

1695 Knockdown of PHOX2B in the retrotrapezoid nucleus reduces the central CO2 chemoreflex in rats

Cardani, S.; Janes, T. A.; Betzner, W.; Pagliardini, S.

10.1101/2023.12.13.571591 — neuroscience — Posted on 2024-02-20

1696 Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight

Zhou, M.; Riva, A.; Gauthier, M.-P. L.; Kladde, M. P.; Ferl, R. J.; Paul, A.-L.

10.1101/2022.11.09.515199 — plant biology — Posted on 2024-02-20

1697 Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes

Patel, D.; Tiusanen, V.; Pihlajamaa, P.; Sahu, B.

10.1101/2024.01.15.575744 — cancer biology — Posted on 2024-02-20

1698 Reversing protonation of weakly basic drugs greatly enhances intracellular diffusion and decreases lysosomal sequestration

DEY, D.; Marciano, S.; Poryvai, A.; Groborz, O.; wohlrabova, L.; Slanina, T.; Schreiber, G.

10.1101/2023.04.19.537456 — biophysics — Posted on 2024-02-20

1699 Single-Molecule Direct RNA Sequencing Reveals the Shaping of Epitranscriptome Across Multiple Species

Xie, Y.-Y.; Zhong, Z.-D.; Chen, H.-X.; Zhang, Z.; Luo, G.-Z.

10.1101/2023.11.16.567334 — biochemistry — Posted on 2024-02-20

1700 Hamster (Cricetus cricetus) and ground squirrel (Spermophilus citellus) in the metropolitan area of Vienna, Austria: Urban development vs. species protection

Rubel, F.

10.1101/2024.02.08.579520 — ecology — Posted on 2024-02-20

1701 Lysosomal integrity suppresses TIR-1/SARM1 aggregation to restrain toxic propagation of p38 innate immunity

Tse-Kang, S. Y.; Pukkila-Worley, R.

10.1101/2024.02.16.580734 — immunology — Posted on 2024-02-20

1702 Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

Toth, B. I.; Bazeli, B.; Janssens, A.; Lisztes, E.; Racsko, M.; Kelemen, B.; Herczeg, M.; Nagy, T. M.; E. Köver, K.; Mitra, A.; Borics, A.; Biro, T.; Voets, T.

10.1101/2024.02.01.578392 — neuroscience — Posted on 2024-02-20

1703 Dysregulation of mitochondrial function by PLK1-mediated PDHA1 phosphorylation promotes Cr(VI)-associated lung cancer progression

ZHANG, Q.; Li, Z.; Rao, X.; Allison, D. B.; Qiao, Q.; Zhang, Z.; Kong, Y.; Zhang, Y.; Wang, R.; Liu, J.; Wang, X.; Li, C.; Mao, F.; Katz, W.; Shao, Q.; Gao, T.; Liu, X.

10.1101/2024.02.16.580630 — cancer biology — Posted on 2024-02-20

1704 Privacy Preserving Epigenetic PaceMaker Stronger Privacy and Improved Efficiency

Goldenberg, M.; Mualem, L.; Shahar, A.; Snir, S.; Akavia, A.

10.1101/2024.02.15.580590 — bioinformatics — Posted on 2024-02-20

1705 The interactive effect of sustained sleep restriction and resistance exercise on skeletal muscle transcriptomics in young females

Knowles, O. E.; Soria, M.; Saner, N. J.; Trewin, A. J.; Alexander, S. E.; Roberts, S. S.; Hiam, D.; Garnham, A.; Drinkwater, E. J.; Aisbett, B.; Lamon, S.

10.1101/2024.02.15.580577 — genomics — Posted on 2024-02-20

1706 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures

Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.

10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-02-20

1707 The influence of talus size and shape on in vivo talocrural hopping kinematics

Behling, A.-V.; Kelly, L.; Welte, L.; Rainbow, M.

10.1101/2024.02.15.580586 — bioengineering — Posted on 2024-02-20

1708 A Machine Learning Enhanced EMS Mutagenesis Probability Map for Efficient Identification of Causal Mutations in Caenorhabditis elegans

Guo, Z.; Wang, S.; Wang, Y.; Wang, Z.; Ou, G.

10.1101/2024.02.15.580605 — genetics — Posted on 2024-02-20

1709 Early-life exposures to specific commensal microbes prevent type 1 diabetes.

Green, J.; Deschaine, J.; Lubin, J.-B.; Flores, J. N.; Maddux, S.; Duranova, T.; Grimes, L.; Planet, P. J.; Eisenlohr, L. C.; Silverman, M. A.

10.1101/2024.02.15.580579 — immunology — Posted on 2024-02-20

1710 Theta-burst direct electrical stimulation remodels human brain networks

Huang, Y.; Zelmann, R.; Hadar, P.; Dezha-Peralta, J.; Richardson, M.; Williams, Z. M.; Cash, S. S.; Keller, C.; Paulk, A. C.

10.1101/2024.02.15.580568 — neuroscience — Posted on 2024-02-20

1711 Generalizable Neural Models of Emotional Engagement and Disengagement

Nanni Zepeda, M.; Evans, T.; Jagger-Rickels, A.; Raz, G.; Hendler, T.; Fan, Y.; Grimm, S.; Walter, M.; Esterman, M.; Zuberer, A.

10.1101/2024.02.15.579332 — neuroscience — Posted on 2024-02-20

1712 Multimodal classification of neurons in the lateral septum

Reid, C. M.; Ren, Y.; Xie, Y.; Turrero Garcia, M.; Tran, D.; Vu, S.; Liu, J.; Adam, M. A.; Hanson, S.; Pisco, A. O.; Harwell, C.

10.1101/2024.02.15.580381 — neuroscience — Posted on 2024-02-20

1713 Healthy dietary choices involve prefrontal mechanisms associated with long-term reward maximization but not cognitive control

Takehana, A.; Tanaka, D.; Arai, M.; Hattori, Y.; Yoshimoto, T.; Matsui, T.; Sadato, N.; Chikazoe, J.; Jimura, K.

10.1101/2024.02.15.580403 — neuroscience — Posted on 2024-02-20

1714 Unveiling Frailty: Comprehensive and Sex-Specific Characterization in Prematurely Aging PolgA Mice

Yilmaz, D.; Singh, A.; Wehrle, E.; Kuhn, G. A.; Mathavan, N.; Mueller, R.

10.1101/2024.02.15.580562 — physiology — Posted on 2024-02-20

1715 Tuning a mechanical model to biological reality: A case study in the LaMSA system of the trap-jaw ant Strumigenys

Anderson, P. S. L.; Jorge, J. F.; Crofts, S. B.; Castro, J. T.; Didcock, R. L.; Cook, A.; Larabee, F. J.; Ilton, M.

10.1101/2024.02.15.580213 — biophysics — Posted on 2024-02-20

1716 Asymmetric Fin Shape changes Swimming Dynamics of Ancient Marine Reptiles' Soft Robophysical Models

Sprumont, H.; Allione, F.; Schwab, F.; Wang, B.; Mucingat, C.; Lunati, I.; Scheyer, T.; Ijspeert, A.; Jusufi, A.

10.1101/2024.02.15.580532 — biophysics — Posted on 2024-02-20

1717 Interpretable Atomistic Prediction and Functional Analysis of Conformational Ensembles and Allosteric States in Protein Kinases Using AlphaFold2 Adaptation with Randomized Sequence Scanning and Local Frustration Profiling

Raisinghani, N.; Alshahrani, M.; Gupta, G.; Tian, H.; Xiao, S.; Tao, P.; Verkhivker, G.

10.1101/2024.02.15.580591 — biophysics — Posted on 2024-02-20

1718 Model-Based Estimation of Active and Passive Muscle Forces Using MRE in Forearm Muscles During 2-DOF Wrist Tasks

Helm, C.; Sergi, F.

10.1101/2024.02.15.580561 — bioengineering — Posted on 2024-02-20

1719 A low-abundance class of Dicer-dependent siRNAs produced from a variety of features in C. elegans

Knittel, T. L.; Montgomery, B. E.; Tate, A. J.; Deihl, E. W.; Nawrocki, A. S.; Hoerndli, F. J.; Montgomery, T. A.

10.1101/2024.02.15.580610 — genomics — Posted on 2024-02-20

1720 mirror determines the far posterior domain in butterfly wings

Chatterjee, M.; Yu, X. Y.; Brady, N. K.; Hatto, G. C.; Reed, R.

10.1101/2024.02.15.580576 — evolutionary biology — Posted on 2024-02-20

1721 Analysis of genetic variation in Macadamia shows evidence of extensive reticulate evolution

Manatunga, S. L.; Furtado, A.; Topp, B.; Alam, M.; Masouleh, A.; Henry, R.

10.1101/2024.02.15.580603 — evolutionary biology — Posted on 2024-02-20

1722 Tissue damage during acute Trypanosoma cruzi infection is associated with reduced reparative regulatory T cell response and can be attenuated by early interleukin-33 administration.

Boccardo, S.; Rodriguez, C.; Furlan, C. L. A.; Abrate, C. P.; Almada, L.; Gimenez, C. M.; Concepcion, M. A. S.; Skewes-Cox, P.; Rao, S. P. S.; Montes, C. L.; Gruppi, A.; Rodriguez, E. V. A.

10.1101/2024.02.15.580513 — immunology — Posted on 2024-02-20

1723 Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy

Castillo, J. G.; Fernandez, S.; Campbell, T.; Williams, J.; Gonzalez-Ventura, D.; Ybarra, J.; Hernandez, N. F.; Wells, E.; Portnoy, D. A.; DuPage, M.

10.1101/2024.02.15.580555 — immunology — Posted on 2024-02-20

1724 Delayed cerebrovascular dysfunction and social deficits after traumatic brain injury

Singh, A.; Gong, S.; Vu, A.; Li, S.; Obenaus, A.

10.1101/2024.02.15.580515 — neuroscience — Posted on 2024-02-20

1725 Neurovascular mitochondrial susceptibility impacts blood-brain barrier function and behavior

Crockett, A. M.; Kebir, H.; Velez-Colon, M. C.; Iascone, D. M.; Cielieski, B.; Rossano, A.; Sehgal, A.; Anderson, S. A.; Alvarez, J. I.

10.1101/2024.02.15.580544 — neuroscience — Posted on 2024-02-20

1726 A Neural Network Approach to Identify Left-Right Orientation of Anatomical Brain MRI

Nishimaki, K.; Iyatomi, H.; Oishi, K.

10.1101/2024.02.15.580574 — neuroscience — Posted on 2024-02-20

1727 A multiscale model of the mammalian liver circadian clock supports synchronization of autonomous oscillations by intercellular communication.

Marri, D. K.; Bhattacharya, S.; Filipovic, D.; Kana, O. Z.; Zhang, Q.; Sluka, J.; Liu, S.

10.1101/2024.02.15.580517 — systems biology — Posted on 2024-02-20

1728 Non-canonical Metabolic and Molecular Effects of Calorie Restriction Are Revealed by Varying Temporal Conditions

Pak, H. H.; Grossberg, A. N.; Sanderfoot, R. R.; Babygirija, R.; Green, C. L.; Koller, M. J.; Dzieciatkowska, M.; Paredes, D. A.; Lamming, D. W.

10.1101/2024.02.15.580502 — physiology — Posted on 2024-02-20

1729 Chemical genetics in C. elegans identifies anticancer mycotoxins chaetocin and chetomin as potent inducers of a nuclear metal homeostasis response

Abraham, E.; Athapaththu, A. M. G. K.; Atanasova, K. R.; Chen, Q.-Y.; Corcoran, T. J.; Piloto, J.; Wu, C.-W.; Ratnayake, R.; Luesch, H.; Choe, K. P.

10.1101/2024.02.15.579914 — pharmacology and toxicology — Posted on 2024-02-20

1730 BMP antagonist CHRDL2 enhances the cancer stem cell phenotype and increases chemotherapy resistance in Colorectal Cancer

Clarkson, E.; Lewis, A.

10.1101/2024.01.23.576664 — cancer biology — Posted on 2024-02-20

1731 The transcription factor RIP140 regulates interferon γ signaling in breast cancer

Jalaguier, S.; Kuehn, A.; Petitpas, C.; Dulom, A.; Jacquemont, R.; Assi, C.; Sixou, S.; Jeschke, U.; Colinge, J.; Cavailles, V.

10.1101/2024.02.15.580503 — cancer biology — Posted on 2024-02-20

1732 DiffGAN: a conditional generative adversarial network for phasing single molecule diffraction data to atomic resolution

Matinyan, S.; Filipcik, P.; Genderen, E. v.; Abrahams, J. P.

10.1101/2024.02.15.580528 — biophysics — Posted on 2024-02-20

1733 A Macroscopic Quantum Heat Engine: Nested Resonant Structures and the Entropic Stability of Life

Baker, J.

10.1101/2024.02.15.580422 — biophysics — Posted on 2024-02-20

1734 Earl Grey: a fully automated user-friendly transposable element annotation and analysis pipeline

Baril, T. J.; Galbraith, J. D.; Hayward, A.

10.1101/2022.06.30.498289 — bioinformatics — Posted on 2024-02-20

1735 A Scalable Optimization Algorithm for Solving the Beltway and Turnpike Problems with Uncertain Measurements

Elder, C. S.; Hoang, M.; Ferdosi, M.; Kingsford, C.

10.1101/2024.02.15.580520 — bioinformatics — Posted on 2024-02-20

1736 Performance of GPT-4 on the American College of Radiology In-Service Examination

Payne, D. L.; Purohit, K.; Borrero, W. M.; Chung, K.; Hao, M.; Mpoy, M.; Jin, M.; Prasanna, P.; Hill, V.

10.1101/2024.02.15.580546 — bioinformatics — Posted on 2024-02-20

1737 Integrated Short-TE and Hadamard-edited Multi-Sequence (ISTHMUS) for Advanced MRS

Hui, S. C. N.; Murali-Manohar, S.; Zollner, H. J.; Hupfeld, K. E.; Davies-Jenkins, C. W.; Gudmundson, A. T.; Song, Y.; Yedavalli, V.; Wisnowski, J. L.; Gagoski, B.; Oeltzschner, G.; Edden, R. A. E.

10.1101/2024.02.15.580516 — bioengineering — Posted on 2024-02-20

1738 Predicting cell type-specific epigenomic profiles accounting for distal genetic effects

Murphy, A. E.; Beardall, W.; Rei, M.; Phuycharoen, M.; Skene, N. G.

10.1101/2024.02.15.580484 — genomics — Posted on 2024-02-20

1739 Limited stress and tissue-specific transcriptional and translational activity of transposable elements in mosquitoes

de Melo, E. D.; Wallau, G. d. L.

10.1101/2024.02.15.580529 — genomics — Posted on 2024-02-20

1740 SCRAPPY - a single cell rapid assay of proteome perturbation in yeast uncovers a joint role of aromatic amino acids and oxidative stress in the toxicity of lipophilic nucleoside analogs

Ghazy, E.; Bidiuk, V. A.; Ryabov, F.; Mitkevich, O. V.; Riabova, O.; Stanishevskiy, Y. M.; Levshin, I. B.; Alexandrova, L. A.; Jasko, M. V.; Makarov, D. A.; Zhgun, A. A.; Avdanina, D. A.; Ermolyuk, A. A.; Kushnirov, V. V.; Egorova, A. P.; Agaphonov, M. O.; Alexandrov, A. I.

10.1101/2024.02.19.580949 — microbiology — Posted on 2024-02-20

1741 Non-Hebbian plasticity transforms transient experiences into lasting memories

Faress, I.; Khalil, V.; Hou, W.-H.; Moreno, A.; Andersen, N.; Fonseca, R.; Piriz, J.; Capogna, M.; Nabavi, S.

10.1101/2023.04.06.535862 — neuroscience — Posted on 2024-02-20

1742 Rapid modeling of an ultra-rare epilepsy patient variant in mice by in utero prime editing

Robertson, C. D.; Davis, P.; Richardson, R. R.; Iffland, P. H.; Vieira, D. C. O.; Steyert, M.; McKeon, P. N.; Romanowski, A. J.; Crutcher, G.; Jasarevic, E.; Wolff, S. B. E.; Mathur, B. N.; Crino, P. B.; Bale, T. L.; Dick, I. E.; Poulopoulos, A.

10.1101/2023.12.06.570164 — neuroscience — Posted on 2024-02-20

1743 Differential transcriptional profiles of vagal sensory neurons in female and male mice.

JO, y.-h.

10.1101/2024.02.15.580501 — neuroscience — Posted on 2024-02-20

1744 Molecular response to multiple trace-element contamination of the European sardine

Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.

10.1101/2024.02.16.580673 — physiology — Posted on 2024-02-20

1745 ChemGLaM: Chemical Genomics Language Models for Compound-Protein Interaction Prediction

Koyama, T.; Tsumura, H.; Matsumoto, S.; Okita, R.; Kojima, R.; Okuno, Y.

10.1101/2024.02.13.580100 — bioinformatics — Posted on 2024-02-20

1746 Specific interactions with phospho-Ubls and allosteric conformational changes regulate the E3 ligase activity of Parkin

Lenka, D. R.; Chaurasiya, S.; Kumar, A.

10.1101/2023.11.21.568018 — biochemistry — Posted on 2024-02-20

1747 Structural perspective on the design of selective DYRK1B inhibitors

Grygier, P.; Pustelny, K.; Menezes, F.; Jemiola-Rzeminska, M.; Suder, P.; Dubin, G.; Czarna, A.

10.1101/2022.12.23.521429 — biochemistry — Posted on 2024-02-20

1748 Estimation of contemporary effective population size in plant populations: limitations of genomic datasets

Gargiulo, R.; Decroocq, V.; Gonzalez-Martinez, S. C.; Paz-Vinas, I.; Aury, J.-M.; Lesur Kupin, I.; Plomion, C.; Schmitt, S.; Scotti, I.; Heuertz, M.

10.1101/2023.07.18.549323 — evolutionary biology — Posted on 2024-02-20

1749 The olivary input to the cerebellum dissociates sensory events from movement plans

Pi, J. S.; Fakharian, M. A.; Hage, P.; Sedaghat-Nejad, E.; Muller, S. Z.; Shadmehr, R.

10.1101/2022.07.11.499614 — neuroscience — Posted on 2024-02-20

1750 Active learning of enhancer and silencer regulatory grammar in a developing neural tissue

Friedman, R. Z.; Ramu, A.; Lichtarge, S.; Wu, Y.; Tripp, L.; Lyon, D.; Myers, C. A.; Granas, D. M.; Gause, M.; Corbo, J. C.; Cohen, B. A.; White, M. A.

10.1101/2023.08.21.554146 — genomics — Posted on 2024-02-20

1751 An optimised protocol for quality control of gene therapy vectors using Nanopore direct RNA sequencing

Zeglinski, K.; Montellese, C.; Ritchie, M. E.; Alhamdoosh, M.; Vonarburg, C.; Bowden, R.; Jordi, M.; Gouil, Q.; Aeschimann, F.; Hsu, A.

10.1101/2023.12.03.569756 — genomics — Posted on 2024-02-20

1752 Long-read genome assembly of the Japanese parasitic wasp Copidosoma floridanum (Hymenoptera: Encyrtidae)

Toga, K.; Sakamoto, T.; Kanda, M.; Tamura, K.; Okuhara, K.; Tabunoki, H.; Bono, H.

10.1101/2023.09.24.559078 — genomics — Posted on 2024-02-20

1753 The timescale and functional form of context-dependence during human value-learning

Tohidi-Moghaddam, M.; Tsetsos, K.

10.1101/2024.02.01.578398 — neuroscience — Posted on 2024-02-20

1754 Temporal Preparation and Statistical Learning: The Influence of Temporal Preparation on Statistical Learning Effects in Complex Temporal Environments

Salet, J. M.; Kruijne, W.; Rijn, H. v.; Zimmermann, E.; Schlichting, N.

10.1101/2022.08.06.502990 — neuroscience — Posted on 2024-02-20

1755 Population genetics of Glossina palpalis gambiensis in the sleeping sickness focus of Boffa (Guinea) before and after eight years of vector control: no effect of control despite a significant decrease of human exposure to the disease

Kagbadouno, M. S.; SERE, M.; Segard, A.; Camara, A. D.; Camara, M.; BUCHETON, B.; Bart, J.-M.; Courtin, F.; DE MEEUS, T.; Ravel, S.

10.1101/2023.07.25.550445 — evolutionary biology — Posted on 2024-02-20

1756 PURA Syndrome-causing mutations impair PUR-domain integrity and affect P-body association

Proske, M.; Janowski, R.; Bacher, S.; Kang, H.-S.; Monecke, T.; Koehler, T.; Hutten, S.; Tretter, J.; Crois, A.; Molitor, L.; Varela-Rial, A.; Fino, R.; Donati, E.; De Fabritiis, G.; Dormann, D.; Sattler, M.; Niessing, D.

10.1101/2023.09.19.558386 — molecular biology — Posted on 2024-02-20

1757 Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

Roscioli, E.; Zucconi Galli Fonseca, V.; Bosch, S. S.; Paciello, I.; Maccari, G.; Batani, G.; Stazzoni, S.; Cardinali, G.; Tiseo, G.; Giordano, C.; Shen, Y.; Capoccia, L.; Ridelfi, M.; Troisi, M.; Manganaro, N.; Mugnaini, C.; Cardamone, D.; De Santi, C.; Ciabattini, A.; Cerofolini, L.; Fragai, M.; Licastro, D.; Nicolau, D. P.; Abdelraouf, K.; Barnini, S.; Menichetti, F.; Falcone, M.; Sala, C.; Kabanova, A.; Rappuoli, R.

10.1101/2024.02.14.580141 — microbiology — Posted on 2024-02-20

1758 A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin.

Singh, M. K.; Bonnell, V.; Silva, I.; Santiago, V. F.; Moraes, M.; Adderley, J.; Doerig, C.; Palmisano, G.; Llinas, M.; Garcia, C. R.

10.1101/2023.09.11.557196 — microbiology — Posted on 2024-02-20

1759 Phase delays between mouse globus pallidus neurons entrained by common oscillatory drive arise from their intrinsic properties, not their coupling

Olivares, E.; Wilson, C. J.; Goldberg, J. A.

10.1101/2024.02.19.580929 — neuroscience — Posted on 2024-02-20

1760 Personalized circuit modeling captures variation in cortical functional connectivity

Cooper, R. A.; Demirtas, M.; Burt, J. B.; Howell, A. M.; Ji, J. L.; Repovs, G.; Sotiropoulos, S.; Anticevic, A.; Murray, J. D.

10.1101/2024.02.19.581085 — neuroscience — Posted on 2024-02-20

1761 Local muscle pressure stimulates the principal receptors for proprioception

Torell, F.; Dimitriou, M.

10.1101/2024.02.06.579058 — neuroscience — Posted on 2024-02-20

1762 Intrinsic structural covariation links cerebellum subregions to the cerebral cortex

Wang, Z.; Diedrichsen, J.; Saltoun, K.; Steele, C. J.; Arnold-Anteraper, S. R.; Yeo, B. T. T.; Schmahmann, J.; Bzdok, D.

10.1101/2024.02.16.580701 — neuroscience — Posted on 2024-02-20

1763 miR-100 and miR-125b Contribute to Enhanced 3D Growth and Invasiveness and can be Functionally Transferred to Silence Target Genes in Recipient Cells

Nelson, H. M.; Qu, S.; Chapman, S. N.; Luthcke, N. L.; Schuster, S. A.; Turnbull, L. A.; Shameer, M.; Guy, L. L.; Liu, X.; Corn, K. C.; Vickers, K. C.; Liu, Q.; Franklin, J. L.; Weaver, A.; Rafat, M.; Coffey, R. J.; Patton, J. G.

10.1101/2024.01.16.575716 — cancer biology — Posted on 2024-02-20

1764 Image processing tools for petabyte-scale light sheet microscopy data

Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.

10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-02-20

1765 Rapid proteome-wide prediction of lipid-interacting proteins through ligand-guided structural genomics

Chou, J. C.-C.; Decosto, C. M.; Chatterjee, P.; Dassama, L. M. K.

10.1101/2024.01.26.577452 — bioinformatics — Posted on 2024-02-20

1766 Investigation of Biomedical Cell Image Cryptography Based on RC4 Technique

Jiang, S.; Kumar, E.

10.1101/2023.12.29.573618 — bioengineering — Posted on 2024-02-20

1767 Engineering mice for female-biased progeny without impacting genetic integrity and litter size

Yosef, I.; Mahata, T.; Chen, Y.; Bar-Joseph, H.; Shalgi, R.; Munitz, A.; Gerlic, M.; Qimron, U.

10.1101/2023.11.21.568055 — bioengineering — Posted on 2024-02-20

1768 Investigation of Two-Component Hydrogel System for the Tissue Regeneration from Simulation

Jiang, S.; Kumar, E.

10.1101/2023.12.28.573564 — biochemistry — Posted on 2024-02-20

1769 Structural mechanisms for VMAT2 inhibition by tetrabenazine

Dalton, M. P.; Cheng, M. H.; Bahar, I.; Coleman, J. A.

10.1101/2023.09.05.556211 — biochemistry — Posted on 2024-02-20

1770 Genomic insights into hybrid zone formation: the role of climate, landscape, and demography in the emergence of a novel hybrid lineage between Populus trichocarpa and P. balsamifera

Bolte, C. E.; Phannareth, T.; Zavala-Paez, M.; Sutara, B. N.; Can, M. F.; Fitzpatrick, M. C.; Holliday, J.; Keller, S. R.; Hamilton, J. A.

10.1101/2023.07.17.549358 — evolutionary biology — Posted on 2024-02-20

1771 CXCL4 signaling and gene induction in human monocytes

YANG, C.; Yuan, R.; Mishra, B.; Bill, R. D.; Zhang, Y.; Du, Y.; Ah Kioon, M. D.; Barrat, F. J.; Ivashkiv, L. B.

10.1101/2022.10.26.513860 — immunology — Posted on 2024-02-20

1772 Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation

Witt, L.; Greenfield, K.; Knoop, K.

10.1101/2023.10.02.560561 — immunology — Posted on 2024-02-20

1773 The gut lactic acid bacteria metabolite, 10-oxo-cis-6,trans-11-octadecadienoic acid, suppresses inflammatory bowel disease in mice by modulating the NRF2 pathway and GPCR-signaling

Ando, M.; Nagata, K.; Takeshita, R.; Ito, N.; Noguchi, S.; Minamikawa, N.; Kodama, N.; Yamamoto, A.; Yashiro, T.; Hachisu, M.; Ichihara, G.; Kishino, S.; Yamamoto, M.; Ogawa, J.; Nishiyama, C.

10.1101/2023.02.22.529495 — immunology — Posted on 2024-02-20

1774 Reconstructing Spatio-Temporal Trajectories of Visual Object Memories in the Human Brain

Lifanov, J.; Griffiths, B. J.; Linde-Domingo, J.; Ferreira, C. S.; Wilson, M.; Mayhew, S. D.; Charest, I.; Wimber, M.

10.1101/2022.12.15.520591 — neuroscience — Posted on 2024-02-20

1775 Aging drives cerebrovascular network remodeling and functional changes in the mouse brain

Bennett, H. C.; Zhang, Q.; Wu, Y.-t.; Manjila, S. B.; Chon, U.; Shin, D.; Vanselow, D. J.; Pi, H.-J.; Drew, P. J.; Kim, Y.

10.1101/2023.05.23.541998 — neuroscience — Posted on 2024-02-20

1776 Retinal waves in adaptive rewiring networks orchestrate convergence and divergence in the visual system

Luna, R.; Li, J.; Bauer, R.; Leeuwen, C. v.

10.1101/2023.10.11.561834 — neuroscience — Posted on 2024-02-20

1777 Impaired updating of working memory representations in individuals with high BMI: evidence for dopaminergic mechanisms

Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.

10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-02-20

1778 Capturing dynamic fear experiences in naturalistic contexts: An ecologically valid fMRI signature integrating brain activation and connectivity

Zhou, F.; Zhang, R.; Yao, S.; Dong, D.; Feng, P.; Kranz, G.; Feng, T.; Becker, B.

10.1101/2023.08.18.553808 — neuroscience — Posted on 2024-02-20

1779 Top-down modulation of sensory processing and mismatch in the mouse posterior parietal cortex

Raltschev, C.; Kasavica, S.; Leonardon, B.; Nevian, T.; Sachidhanandam, S.

10.1101/2023.05.11.540431 — neuroscience — Posted on 2024-02-20

1780 Rejuvenation of Senescent Cells by Low Frequency Ultrasound without Senolysis

Kureel, S. K.; Maroto, R.; Powell, S.; Margadant, F.; Blair, B.; Rasmussen, B.; Sheetz, M.

10.1101/2022.12.08.519320 — physiology — Posted on 2024-02-20

1781 Brain-Derived CCN3 Is An Osteoanabolic Hormone That Sustains Bone in Lactating Females

Babey, M. E.; Krause, W. C.; Herber, C. B.; Chen, K.; Torok, Z.; Nikkannen, J.; Rodriquez, R.; Zhang, X.; Castro-Navarro, F.; Wang, Y.; Villeda, S.; Lane, N. E.; Scheller, E. L.; Chan, C. K. F.; Ambrosi, T. H.; Ingraham, H. A.

10.1101/2023.08.28.554707 — neuroscience — Posted on 2024-02-19

1782 Reconstructing prevalence dynamics of wildlife pathogens from pooled and individual samples

Borremans, B.; Falvo, C. A.; Crowley, D. E.; Hoegh, A.; Lloyd-Smith, J. O.; Peel, A. J.; Restif, O.; Ruiz-Aravena, M.; Plowright, R. K.

10.1101/2023.11.02.565200 — ecology — Posted on 2024-02-19

1783 Detecting superspreaders in wildlife reservoirs of disease

Konzen, E.; Delahay, R. J.; Hodgson, D. J.; McDonald, R. A.; Brooks Pollock, E.; Spencer, S. E. F.; McKinley, T. J.

10.1101/2024.01.26.576600 — ecology — Posted on 2024-02-19

1784 Hearing what is being said: The distributed neural substrate for early speech interpretation

Clarke, A.; Tyler, L. K.; Marslen-Wilson, W. D.

10.1101/2023.03.23.533971 — neuroscience — Posted on 2024-02-19

1785 Genome assembly and genomic architecture of a prominent cold-resistant rapeseed germplasm

Wu, Z.; Zheng, G.; Sun, Y.; Dong, X.; Wang, Y.; Li, H.; Niu, Y.; Huang, Z.; Hu, J.; Liu, Z.

10.1101/2023.11.12.566742 — genomics — Posted on 2024-02-19

1786 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Markenscoff-Papadimitriou, E.; Reed, R. D.

10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-19

1787 Cooperativity and additivity in plant enhancers

Jores, T.; Tonnies, J.; Mueth, N. A.; Romanowski, A.; Fields, S.; Cuperus, J.; Queitsch, C.

10.1101/2023.11.21.568158 — plant biology — Posted on 2024-02-19

1788 Altered NRG1/ErbB4 signaling and cholesterol metabolism dysregulation are key pathomechanisms in VRK1-related motor neuropathies and motor neuron diseases

Hamze, Z.; Humbert, C.; Rihan, K.; Roeckel-Trevisiol, N.; Castro, C.; Lenfant, N.; Robert, C.; Bertaux, K.; Jabbour, R.; Bernard-Marissal, N.; Megarbane, A.; DELAGUE, V.

10.1101/2024.02.19.581053 — genetics — Posted on 2024-02-19

1789 Experimental design impacts the vector competence of Ornithodoros ticks for African swine fever virus: a meta-analysis of published evaluations

Bernard, J.; Madeira, S.; Otte, J.; Boinas, F.; Le Potier, M.-F.; Vial, L.; Jourdan-Pineau, H.

10.1101/2023.11.10.566648 — ecology — Posted on 2024-02-19

1790 Valorization of Organic Fraction of Municipal Solid Waste Through Production of Volatile Fatty Acids (VFAs) and Biogas

Borhany, H.

10.1101/2023.06.21.545938 — microbiology — Posted on 2024-02-19

1791 Natural Variation in Age-Related Dopamine Neuron Degeneration is Glutathione-Dependent and Linked to Life Span

Coleman, C. R.; Pallos, J.; Arreola-Bustos, A.; Wang, L.; Raftery, D.; Promislow, D. E. L.; Martin, I.

10.1101/2024.02.12.580013 — neuroscience — Posted on 2024-02-19

1792 Neural circuit models for evidence accumulation through choice-selective sequences

Brown, L. S.; Cho, J. R.; Bolkan, S. S.; Nieh, E. H.; Schottdorf, M.; Tank, D. W.; Brody, C. D.; Witten, I. B.; Goldman, M. S.

10.1101/2023.09.01.555612 — neuroscience — Posted on 2024-02-19

1793 GexMolGen: Cross-modal Generation of Hit-like Molecules via Large Language Model Encoding of Gene Expression Signatures

Cheng, J.; Pan, X.; Yang, K.; Cao, S.; Liu, B.; Yuan, Y.; Yan, Q.

10.1101/2023.11.11.566725 — bioinformatics — Posted on 2024-02-19

1794 Site-specific Effector Protein Functionalization to Create Bead-based Avidity Model Systems

Hackl, M.; Jayachandran, D.; Ramdin, K.; Zhong, T.; Travers, T.; Gnanakaran, S.; Chundawat, S. P. S.

10.1101/2023.03.27.534459 — bioengineering — Posted on 2024-02-19

1795 Structural and biochemical characterization of an encapsulin-associated rhodanesefrom Acinetobacter baumannii

Benisch, R.; Giessen, T. W.

10.1101/2024.02.19.581022 — biochemistry — Posted on 2024-02-19

1796 Discovery of Alkenyl Oxindole as a Novel PROTAC Moiety for Targeted Protein Degradation via CRL4DCAF11 Recruitment

Wang, Y.; Wei, T.; Zhao, M.; Huang, A.; Sun, F.; Chen, L.; Lin, R.; Xie, Y.; Zhang, M.; Xu, S.; Sun, Z.; Hong, L.; Wang, R.; Tian, R.; Li, G.

10.1101/2024.02.15.580430 — biochemistry — Posted on 2024-02-19

1797 Dynamics of interdomain rotation facilitates FtsZ filament assembly

Chakraborty, J.; Poddar, S. M.; Dutta, S.; Bahulekar, V.; Harne, S.; SRINIVASAN, R.; Gayathri, P.

10.1101/2022.10.13.512043 — biochemistry — Posted on 2024-02-19

1798 Single-particle track colocalization using CoPixie reveals the impact of cancer-associated POT1 mutations on telomerase-telomere interactions

Prince, S.; Maguemoun, K.; Ferdebouh, M.; Querido, E.; Derumier, A.; Chartrand, P.

10.1101/2024.02.19.580537 — biochemistry — Posted on 2024-02-19

1799 Using Neural Style Transfer to study the evolution of animal signal design: A case study in an ornamented fish

Hejja-Brichard, Y.; Million, K.; Renoult, J. P.; Mendelson, T. C.

10.1101/2023.03.13.532060 — animal behavior and cognition — Posted on 2024-02-19

1800 A cautionary tale on organelle proteome prediction algorithms: limits and opportunities

Gould, S. B.; Magiera, J.; Garcia Garcia, C.; Raval, P. K.

10.1101/2023.12.18.572050 — cell biology — Posted on 2024-02-19

1801 GATAD2B containing NuRD complex drives R-loop dependent chromatin boundary formation at double strand breaks

Liu, Z.; Ajit, K.; Wu, Y.; Zhu, W.-G.; Gullerova, M.

10.1101/2024.02.19.581003 — molecular biology — Posted on 2024-02-19

1802 TIRR regulates mRNA export and association with P bodies in response to DNA damage

Glossop, M. S.; Chelysheva, I.; Ketley, R. F.; Alagia, A.; Gullerova, M.

10.1101/2024.02.19.580988 — molecular biology — Posted on 2024-02-19

1803 Tetrameric INTS6-SOSS1 complex facilitates DNA:RNA hybrid autoregulation at double-strand breaks

Long, Q.; Ajit, K.; Sedova, K.; Haluza, V.; Stefl, R.; Dokaneheifard, S.; Beckedorff, F.; Valencia, M. G.; Sebesta, M.; Shiekhattar, R.; Gullerova, M.

10.1101/2024.02.19.580984 — molecular biology — Posted on 2024-02-19

1804 Activation of Macrophages by Extracellular Vesicles Derived from Babesia-infected Red Blood Cells

Hagos, B.; Brasov, I.; Branscome, H.; Kashanchi, F.; Ben Mamoun, C.; Molestina, R. E.

10.1101/2024.02.19.581030 — microbiology — Posted on 2024-02-19

1805 Glutathione metabolism impacts fungal virulence by modulating the redox environment

Black, B.; Roque da Silva, L. B.; Hu, G.; Qu, X.; Smith, D. F.; Magana, A. A.; Horianopoulos, L. C.; Caza, M.; Attarian, R.; Foster, L. J.; Casadevall, A.; Kronstad, J. W.

10.1101/2024.02.19.581054 — microbiology — Posted on 2024-02-19

1806 Mixed signatures for subcritical dynamics in rodent hippocampus during sleep and awake epochs

Garg, P.

10.1101/2023.10.30.564597 — neuroscience — Posted on 2024-02-19

1807 Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature

Abiega, O.; Senovilla-Ganzo, R.; El-Ouraoui, M.; Muro Garcia, T.; Ruiz Clavijo, L.; Garcia Moreno, F.; Fitzsimons, C. P.; Martin Suarez, S.; Encinas Perez, J. M.

10.1101/2024.01.26.577346 — neuroscience — Posted on 2024-02-19

1808 Chloroplast Cell-Free Systems from Different Plant Species as a Rapid Prototyping Platform

Boehm, C. V.; Inckemann, R.; Burgis, M.; Baumann, J.; Brinkmann, C. K.; Lipinska, K. E.; Gilles, S.; Freudigmann, J.; Seiler, V.; Clark, L. G.; Jewett, M. C.; Voll, L. M.; Niederholtmeyer, H.

10.1101/2024.02.19.580994 — synthetic biology — Posted on 2024-02-19

1809 Qualitative and Quantitative Concentration-Response Modelling of Gene Co-expression Networks to Unlock Hepatotoxic Mechanisms for Next Generation Chemical Safety Assessment

Kunnen, S. J.; Arnesdotter, E.; Willenbockel, C. T.; Vinken, M.; van de Water, B.

10.1101/2023.02.01.526628 — pharmacology and toxicology — Posted on 2024-02-19

1810 PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy

Yoshida, T.; Latt, K. Z.; Rosenberg, A. Z.; Santo, B. A.; Myakala, K.; Ishimoto, Y.; Zhao, Y.; Shrivastav, S.; Jones, B. A.; Yang, X.; Wang, X.; Tutino, V. M.; Sarder, P.; Levi, M.; Okamoto, K.; Winkler, C. A.; Kopp, J. B.

10.1101/2022.10.03.510678 — pathology — Posted on 2024-02-19

1811 Improving bacterial metagenomic research through long read sequencing

Greenman, N. A.; Hassouneh, S. A.-D.; Johnston, C.; Azarian, T.

10.1101/2023.10.31.564966 — bioinformatics — Posted on 2024-02-19

1812 Revisiting pangenome openness with k-mers

Parmigiani, L.; Wittler, R.; Stoye, J.

10.1101/2022.11.15.516472 — bioinformatics — Posted on 2024-02-19

1813 Design and optimization of silicon-based electrokinetic microchip for sensitive detection of small extracellular vesicles

Talebian Gevari, M.; Sahu, S. S.; Stridfeldt, F.; Haag, P.; Viktorsson, K.; Lewensohn, R.; Gori, A.; Cretich, M.; Dev, A.

10.1101/2022.08.17.504250 — bioengineering — Posted on 2024-02-19

1814 Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses

Goto, Y.; Miyafusa, T.; Honda, S.

10.1101/2024.02.18.580912 — biochemistry — Posted on 2024-02-19

1815 Visualizing the M2 muscarinic acetylcholine receptor activation regulated by aromatic ring dynamics

Gong, Z.; Zhang, X.; Liu, M.; Jin, C.; Hu, Y.

10.1101/2024.02.18.580854 — biochemistry — Posted on 2024-02-19

1816 Combining computational biology and experimental knowledge to draw a structural profile of the active membrane-assembled NADPH oxidase complex

Aimeur, S. Z.; Fas, B. A.; Serfaty, X.; Santuz, H.; Sacquin-Mora, S.; Bizouarn, T.; Taly, A.; BACIOU, L.

10.1101/2024.02.19.579638 — biochemistry — Posted on 2024-02-19

1817 Kinetic principles of chemical cross-link formation for protein-protein interactions

Kammer, K.-M.; Pellarin, R.; Stengel, F.

10.1101/2024.02.19.580987 — biochemistry — Posted on 2024-02-19

1818 Clonal analysis of fetal hematopoietic stem/progenitor cell subsets reveals how post-transplantation capabilities are distributed

Stonehouse, O.; Biben, C.; Weber, T. S.; Garnham, A.; Fennell, K.; Farley, A.; Terreaux, A.; Alexander, W.; Dawson, M.; Naik, S.; Taoudi, S.

10.1101/2024.02.19.579920 — developmental biology — Posted on 2024-02-19

1819 Anastasis induced by bee venom in normal cells compared to persistent cell death in breast cancer cells

Tetikoglu, S.; Uzuner, U.; Celik Uzuner, S.

10.1101/2024.02.18.579605 — molecular biology — Posted on 2024-02-19

1820 To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes

Le Huray, K. I. P.; Woerner, T. P.; Moreira, T.; Reinhardt-Szyba, M.; Devine, P. W. A.; Bond, N. J.; Fort, K. L.; Makarov, A. A.; Sobott, F.

10.1101/2024.02.19.581059 — molecular biology — Posted on 2024-02-19

1821 A UL26-PIAS1 complex antagonizes anti-viral gene expression during Human Cytomegalovirus infection

Ciesla, J. H.; Huang, K.-L.; Wagner, E. J.; Munger, J.

10.1101/2024.02.19.580933 — molecular biology — Posted on 2024-02-19

1822 Tissue resident cells differentiate S. aureus from S. epidermidis via IL-1beta following barrier disruption in healthy human skin disruption in healthy human skin

Lang, J. C.; Brutscher, A.; Ehrstrom, M.; Melican, K.

10.1101/2024.02.19.580932 — microbiology — Posted on 2024-02-19

1823 RfaA (YqhY), a novel adaptor protein, controls metabolite-sensitive protein degradation in Bacillus subtilis

Wicke, D.; Lentes, S.; Herrfurth, C.; Toedter, D.; Stannek-Goebel, L.; Commichau, F. M.; Feussner, I.; Stulke, J.

10.1101/2024.02.19.580884 — microbiology — Posted on 2024-02-19

1824 Warfarin analogs target disulfide bond-forming enzymes and suggest a residue important for quinone and coumarin binding

Chavez, D.; Amarquaye, G. N.; Mejia-Santana, A.; Dyotima, ; Ryan, K.; Zeng, L.; Landeta, C.

10.1101/2024.02.18.580799 — microbiology — Posted on 2024-02-19

1825 Discovering and exploring the hidden diversity of human gut viruses using highly enriched virome samples

Zolfo, M.; Silverj, A.; Blanco-Miguez, A.; Manghi, P.; Rota-Stabelli, O.; Heidrich, V.; Jensen, J.; Maharjan, S.; Franzosa, E.; Menni, C.; Visconti, A.; Pinto, F.; Ciciani, M.; Huttenhower, C.; Cereseto, A.; Asnicar, F.; Kitano, H.; Yamada, T.; Segata, N.

10.1101/2024.02.19.580813 — microbiology — Posted on 2024-02-19

1826 Journey to the center of the phage; revealing the ejectosome of Pectobacterium bacteriophage {Phi}M1

Eruera, A.-R.; Hodgkinson-Bean, J.; Rutter, G. L.; Hills, F. R.; Kumaran, R.; Crowe, A. J. M.; Jadav, N.; McJarrow-Keller, K. L.; Jorge, F. E.; Hyun, J.; Kim, H.; Ryu, B.; Bostina, M.

10.1101/2024.02.19.577657 — microbiology — Posted on 2024-02-19

1827 Efficacy of Topical Strategies to Prevent the Onset of Root Caries Lesions, In vitro.

Valenzuela-Ramos, R.; Leon, S.; Giacaman, R. A.

10.1101/2024.02.19.581042 — microbiology — Posted on 2024-02-19

1828 Polyamine-mediated sensitization of Klebsiella pneumoniae to macrolides through a dual mode of action

Adams, J. M. E.; Moulding, P. B.; El-Halfawy, O. M.

10.1101/2024.02.18.580908 — microbiology — Posted on 2024-02-19

1829 Structural basis of Ebola virus nucleocapsid assembly and functions

Fujita-Fujiharu, Y.; Hu, S.; Hirabayashi, A.; Takamatsu, Y.; Ng, Y. N.; Houri, K.; Muramoto, Y.; Nakano, M.; Sugita, Y.; Noda, T.

10.1101/2024.02.19.580633 — microbiology — Posted on 2024-02-19

1830 Genetic potential for aerobic respiration and denitrification in globally distributed respiratory endosymbionts

Speth, D. R.; Zeller, L. M.; Graf, J. S.; Overholt, W. A.; Kuesel, K.; Milucka, J.

10.1101/2024.02.19.580942 — microbiology — Posted on 2024-02-19

1831 Mod5 mediates a molecular trade-off between optimal gene expression and antifungal resistance.

Bruch, A.; Lazarova, V.; Krueger, T.; Schaeuble, S.; Kelani, A. A.; Lehenberger, P.; Kniemeyer, O.; Panagiotou, G.; Blango, M. G.

10.1101/2024.02.19.578369 — microbiology — Posted on 2024-02-19

1832 Robust SARS-CoV-2 Neutralizing Antibodies Sustained through Three Months Post XBB.1.5 mRNA Vaccine Booster

Wang, Q.; Mellis, I. A.; Guo, Y.; Gherasim, C.; Valdez, R.; Gordon, A.; Liu, L.; Ho, D. D.

10.1101/2024.02.16.580687 — immunology — Posted on 2024-02-19

1833 Activated STING in the thymus alters T cell development and selection leading to autoimmunity

Deng, Z.; Law, C. S.; Kurra, S.; Simchoni, N.; Shum, A. K.

10.1101/2024.02.17.580803 — immunology — Posted on 2024-02-19

1834 A temperature-inducible protein module for control of mammalian cell fate

Benman, W.; Huang, Z. D.; Iyengar, P.; Wilde, D.; Mumford, T.; Bugaj, L.

10.1101/2024.02.19.581019 — synthetic biology — Posted on 2024-02-19

1835 COVID-19 during pregnancy alters circulating extracellular vesicle cargo and their effects on trophoblast

Golden, T. N.; Mani, S.; Anton, L.; Conine, C. C.; Linn, R. L.; Leite, R.; Kaufman, B. A.; Mainigi, M.; Trigg, N. A.; Wilson, A.; Strauss, J. F.; Parry, S.; Simmons, R. A.

10.1101/2024.02.17.580824 — pathology — Posted on 2024-02-19

1836 A Genome-Wide Arrayed CRISPR Screen Reveals PLSCR1 as an Intrinsic Barrier to SARS-CoV-2 Entry

10.1101/2024.02.16.580725 — immunology — Posted on 2024-02-19

1837 Stability from subspace rotations and traveling waves

Batabyal, T.; Brincat, S. L.; Donoghue, J. A.; Lundqvist, M.; Mahnke, M. K.; Miller, E. K.

10.1101/2024.02.19.581020 — neuroscience — Posted on 2024-02-19

1838 Mechanical convergence in mixed populations of mammalian epithelial cell

Gauquelin, E.; Kuromiya, K.; Namba, T.; Ikawa, K.; Fujita, Y.; Ishihara, S.; Sugimura, K.

10.1101/2024.02.18.580863 — cell biology — Posted on 2024-02-19

1839 Two serial filters determine P2X7R cation selectivity, Ser342 in the central pore and lateral acidic residues at the cytoplasmic interface

Markwardt, F.; Schoen, E.; Raycheva, M.; Malisetty, A. S.; Hawro Yakoob, S.; Berthold, M.; Schmalzing, G.

10.1101/2024.02.19.579953 — biophysics — Posted on 2024-02-19

1840 EGF/STAT1 signals to maintain ECM1 expression in hepatic homeostasis are disrupted by IFNγ/NRF2 in chronic liver disease

Li, Y.; Link, F.; Fan, W.; Nwosu, Z. C.; Pioronska, W.; Gould, K.; Meyer, C.; Yao, Y.; Hammad, S.; Feng, R.; Liu, H.; Shao, C.; Sun, B.; Ding, H.; Liebe, R.; Ebert, M. P. A.; Weng, H.-L.; ten Dijke, P.; Dooley, S.; Wang, S.

10.1101/2024.02.17.580798 — cell biology — Posted on 2024-02-19

1841 Construction and Application of a Technical Platform for Determining Cell Cycle- and Autophagy-Associated Cellular Uptake of Lipid-Based Nanoparticles

Wang, Y.; Luo, G.; Wang, H.; Zheng, Y.; Zhou, W.; Lin, J.; Chen, B.; Sui, M.

10.1101/2024.02.19.579560 — cell biology — Posted on 2024-02-19

1842 Sildenafil amplifies calcium influx and insulin secretion in pancreatic β cells

Murao, N.; Morikawa, R.; Seino, Y.; Shimomura, K.; Maejima, Y.; Yamada, Y.; Suzuki, A.

10.1101/2024.02.17.580848 — cell biology — Posted on 2024-02-19

1843 D-mannose suppresses macrophage release of extracellular vesicles and ameliorates type 2 diabetes

Zhang, S.; Sui, B.-D.

10.1101/2024.02.18.580856 — cell biology — Posted on 2024-02-19

1844 TomoNet: A streamlined cryoET software pipeline with automatic particle picking on flexible lattices

Wang, H.; Liao, S.; Yu, X.; Zhang, J.; Zhou, Z. H.

10.1101/2024.02.17.580557 — cell biology — Posted on 2024-02-19

1845 Inhibition of Soluble Epoxide Hydrolase Reduces Inflammation and Myocardial Injury in Arrhythmogenic Cardiomyopathy

Panigrahy, D.; Kelly, A.; Wang, W.; Yang, J.; Hwang, S. H.; Gillespie, M.; Howard, I.; Bueno-Beti, C.; Asimaki, A.; Penna, V.; Lavine, K.; Edin, M.; Zeldin, D.; Hammock, B.; Saffitz, J.

10.1101/2024.02.17.580812 — cell biology — Posted on 2024-02-19

1846 Expression of Plasmodium Major Facilitator Superfamily Protein in Transporters-Delta Candida Identifies a Drug Transporter

Maurya, P.; Kumar, M.; Jain, R.; Singh, H.; Thaer Abdulhameed Almuqdadi, H.; Gupta, A.; Arenz, C.; Gaur, N.; Singh, S.

10.1101/2024.02.18.580920 — cell biology — Posted on 2024-02-19

1847 Biogenic nanoparticles from liquid and solid matrices: biochemical and biophysical properties of Extracellular Vesicles-enriched samples from human plasma and skeletal muscle tissue.

Mangolini, V.; Radeghieri, A.; Piva, S.; Cattaneo, S.; Brucale, M.; Valle, F.; Balestri, A.; Montis, C.; Latronico, N.; Bergese, P.; Paolini, L.

10.1101/2024.02.19.580950 — cell biology — Posted on 2024-02-19

1848 Allele-level visualization of transcription and chromatin by high-throughput imaging

Almansour, F.; Keikhosravi, A.; Pegoraro, G.; Misteli, T.

10.1101/2024.02.19.580973 — cell biology — Posted on 2024-02-19

1849 Large-scale visualisation of α-synuclein oligomers in Parkinson's disease brain tissue

Andrews, R.; Fu, B.; Toomey, C. E.; Breiter, J. C.; Lachica, J.; Tian, R.; Beckwith, J. S.; Needham, L.-M.; Chant, G. J.; Loiseau, C.; Deconfin, A.; Baspin, K.; Magill, P. J.; Jaunmuktane, Z.; Freeman, O. J.; Taylor, B. J. M.; Hardy, J.; Lashley, T.; Ryten, M.; Vendruscolo, M.; Wood, N. W.; Weiss, L. E.; Gandhi, S.; Lee, S. F.

10.1101/2024.02.17.580698 — neuroscience — Posted on 2024-02-19

1850 Novel therapies for cancer-induced bone pain

Haroun, R.; Gossage, S. J.; Iseppon, F.; Fudge, A.; Caxaria, S.; Arcangeletti, M.; Leese, C.; Davletov, B.; Cox, J. J.; Sikandar, S.; Welsh, F.; Chessell, I. P.; Wood, J.

10.1101/2024.02.19.580951 — neuroscience — Posted on 2024-02-19

1851 Leveraging Transcriptomics-Based Approaches to Enhance Genomic Prediction: Integrating SNP weights and gene-networks for Cotton Fibre Quality Improvement

Khalilisamani, N.; Li, Z.; Pettolino, F.; Moncuquet, P.; Reverter, A.; MacMillan, C. P.

10.1101/2024.02.14.580398 — genomics — Posted on 2024-02-19

1852 Integrative phylogenetic analysis of the genus Episoriculus (Mammalia: Eulipotyphla: Soricidae)

Liu, Y.; Wang, X.; Wan, T.; Liao, R.; Chen, S.; Liu, S.; Yue, B.

10.1101/2024.02.15.580476 — zoology — Posted on 2024-02-19

1853 Taurine/chenodeoxycholic acid ratio as a circulating biomarker of insidious vitamin B12 deficiency in humans

Baghel, M.; Shi, S. L.; Patel, H.; Velagapudi, V.; Ali, A. M.; Yadav, V. K.

10.1101/2024.02.15.580499 — pharmacology and toxicology — Posted on 2024-02-19

1854 Patient-derived functional immuno-oncology platform identifies responders to ATR inhibitor and immunotherapy combinations in ovarian cancer

Nagaraj, A. S.; Salko, M.; Sirsikar, A.; Erkan, E. P.; Pietilä, E. A.; Niemiec, I.; Bao, J.; Marchi, G.; Szabo, A.; Nowlan, K.; Pikkusaari, S.; Kanerva, A.; Tapper, J.; Koivisto-Korander, R.; Kauppi, L.; Hautaniemi, S.; Vähärautio, A.; Tang, J.; Haltia, U.-M.; Kekäläinen, E.; Virtanen, A.; Salo, T.; Färkkilä, A.

10.1101/2024.02.15.579904 — cancer biology — Posted on 2024-02-19

1855 Single nuclei and spatial transcriptomes suggest a stratification of papillary and anaplastic thyroid cancer cells

Tourneur, A.; Rodrigues Vitoria, J.; Saiselet, M.; Craciun, L.; Larsimont, D.; Lefort, A.; Libert, F.; Maenhaut, C.; Costagliola, S.; Tarabichi, M.; Romitti, M.; Detours, V.

10.1101/2024.02.15.580495 — cancer biology — Posted on 2024-02-19

1856 Probing drug-target engagement of soluble Gαi1 protein using the SolThermoBRET thermal shift assay

Brod, O.; Plevako, D.; Perera, T.; Hompluem, P.; Koers, E. J.; Hilbert, M.; Sykes, D. A.; Veprintsev, D.

10.1101/2024.02.15.580002 — biophysics — Posted on 2024-02-19

1857 Mapping Spatial Patterns to Energetic Benefits in Groups of Flow-coupled Swimmers

Heydari, S.; Hang, H.; Kanso, E.

10.1101/2024.02.15.580536 — biophysics — Posted on 2024-02-19

1858 Molecular chaperone BiP controls activity of the ER stress sensor Ire1 through interactions with its oligomers

Dawes, S.; Hurst, N.; Grey, G.; Wieteska, L.; Wright, N. V.; Manfield, I. W.; Hussain, M. H.; Kalverda, A. P.; Lewandowski, J. R.; Chen, B.; Zhuravleva, A.

10.1101/2024.02.16.579620 — biophysics — Posted on 2024-02-19

1859 Matching provides efficient decisions

Kubanek, J.

10.1101/2024.02.15.580481 — animal behavior and cognition — Posted on 2024-02-19

1860 Tracing the evolutionary history of Tunisian HPV 16 and 18 across the genetic diversity in L1 gene

Ardhaoui, M.; Dekhil, N.; Bouslama, Z.; Bel Hadj Rhouma, R.; Fehri, E.; Ennaifer, E.; Guizani, I.

10.1101/2024.02.15.580472 — evolutionary biology — Posted on 2024-02-19

1861 Developmental effects of barium in planaria

Molano, A.

10.1101/2024.02.15.580538 — developmental biology — Posted on 2024-02-19

1862 Metformin Enhances Antibody-Mediated Recognition of HIV-Infected CD4+ T-Cells by Decreasing Viral Release

Fert, A.; Richard, J.; Raymond Marchand, L.; Planas, D.; Routy, J.-P.; Chomont, N.; Finzi, A.; Ancuta, P.

10.1101/2024.02.15.580166 — immunology — Posted on 2024-02-19

1863 Brainwide mesoscale functional networks revealed by focal infrared neural stimulation of the amygdala

Ping, A.; Wang, J.; Garcia Cabezas, M. A.; Li, L.; Zhang, J.; Zhu, J.; Gothard, K. M.; Roe, A. W.

10.1101/2024.02.14.580397 — neuroscience — Posted on 2024-02-19

1864 Brain substates induced by DMT relate to sympathetic output and meaningfulness of the experience

Pasquini, L.; Simon, A.; Gallen, C.; Kettner, H.; Roseman, L.; Gazzaley, A.; Carhart-Harris, R.; Timmermann, C.

10.1101/2024.02.14.580356 — neuroscience — Posted on 2024-02-19

1865 Sympathetic Signals Promote Immunosuppressive Neutrophils in Lung Tumors

Liu, J.; Qiu, M.; Wang, W.; Cao, Y.; Yang, F.; Chen, K.; Chen, J.; Yang, J.

10.1101/2024.02.15.580434 — neuroscience — Posted on 2024-02-19

1866 Emotional Content and Semantic Structure of Dialogues Predict Interpersonal Neural Synchrony in the Prefrontal Cortex: a Hyperscanning Studywith Functional Near-Infrared Spectroscopy

Carollo, A.; Stella, M.; Lim, M.; Bizzego, A.; Esposito, G.

10.1101/2024.02.15.580458 — neuroscience — Posted on 2024-02-19

1867 Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor.

Hetzer, S.; Bellary, R.; Torrens, J. N.; Grimaldi, R. F.; Evanson, N. K.

10.1101/2024.02.15.580435 — neuroscience — Posted on 2024-02-19

1868 Morphing Cholinesterase Inhibitor Amiridine into Multipotent Drugs for the Treatment of Alzheimer's Disease

Mezeiova, E.; Prchal, L.; Hrabinova, M.; Muckova, L.; Pulkrabkova, L.; Soukup, O.; Misiachna, A.; Janousek, J.; Fibigar, J.; Kucera, T.; Horak, M.; Makhaeva, G. F.; Korabecny, J.

10.1101/2024.02.15.580468 — neuroscience — Posted on 2024-02-19

1869 Jianpi Jiedu Recipe inhibits proliferation through reactive oxygen species-induced incomplete autophagy and reduces PD-L1 expression in colon cancer

Cheng, L.; Xu, L.; Yuan, H.; Zhao, Q.; Yue, W.; Ma, S.; Wu, X.; Gu, D.; Sun, Y.; Shi, H.; Xu, J.

10.1101/2024.02.15.580471 — pharmacology and toxicology — Posted on 2024-02-19

1870 Contributions of PD1 and PD2 to the difference spectrum in the Soret region in Photosystem II

Boussac, A.; Sugiura, M.; Nagao, R.; Noguchi, T.; Rutherford, A. W.; Selles, J.

10.1101/2024.02.15.580457 — biophysics — Posted on 2024-02-19

1871 Vaginal lactobacilli produce anti-inflammatory beta-carboline compounds.

Webber, C. A.; Glick, V. J.; Martin, M.; Kim, C.; Ahmad, M.; Simmons, L. E.; Bang, S.; Chao, M. C.; Howard, N. C.; Fortune, S. M.; Beura, L. K.; Lee, S. Y.; Clardy, J.; Kim, K. H.; Gopinath, S.

10.1101/2024.02.19.580919 — microbiology — Posted on 2024-02-19

1872 Shared and diverging neural dynamics underlying false and veridical perception

Haarsma, J.; Hetenyi, D.; Kok, P.

10.1101/2023.11.16.567367 — neuroscience — Posted on 2024-02-19

1873 Evaluating models of the ageing BOLD response

Henson, R. N.; Olszowy, W.; Tsvetanov, K. A.; Yadav, P. S.; CamCAN, ; Zeidman, P.

10.1101/2023.08.24.554634 — neuroscience — Posted on 2024-02-19

1874 New observations of fluorescent organisms in the Banda Sea and in the Red Sea

Poding, L. H.; Jaegers, P.; Huhn, M.; Herlitze, S.; Senen, B.; Limmon, G. V.

10.1101/2023.09.22.559034 — zoology — Posted on 2024-02-19

1875 Impact of rice GENERAL REGULATORY FACTOR14h (GF14h) on low-temperature seed germination and its application to breeding

Sugimura, Y.; Oikawa, K.; Sugihara, Y.; Utsushi, H.; Kanzaki, E.; Ito, K.; Ogasawara, Y.; Fujioka, T.; Takagi, H.; Shimizu, M.; Shimono, H.; Terauchi, R.; Abe, A.

10.1101/2024.02.16.580620 — plant biology — Posted on 2024-02-19

1876 FLOWERING LOCUS C integrates carbon and nitrogen signaling for the proper timing of flowering in Arabidopsis

Gramma, V.; Olas, J. J.; Zacharaki, V.; Ponnu, J.; Luzarowska, U.; Musialak-Lange, M.; Wahl, V.

10.1101/2024.02.15.580522 — plant biology — Posted on 2024-02-19

1877 Young guard cells function dynamically despite low mechanical anisotropy but gain efficiency during stomatal maturation in Arabidopsis thaliana

Jaafar, L.; Chen, Y.; Keynia, S.; Turner, J. A.; Anderson, C. T.

10.1101/2024.02.15.580511 — plant biology — Posted on 2024-02-19

1878 Expression of a mammalian RNA demethylase increases flower number and floral stem branching in Arabidopsis thaliana

Markel, K.; Waldburger, L. M.; Shih, P.

10.1101/2024.02.15.580558 — plant biology — Posted on 2024-02-19

1879 miR858a-encoded peptide, miPEP858a, interacts with miR858a promoter and requires C-terminus for the associated functions

Gautam, H.; Sharma, A.; Anyatama, A.; Trivedi, P. K.

10.1101/2024.02.16.580742 — plant biology — Posted on 2024-02-19

1880 Differences in RAD51 transcriptional response and cell cycle dynamics reveal varying sensitivity to DNA damage among Arabidopsis thaliana root cell types

Kutashev, K.; Meschichi, A.; Reeck, S.; Fonseca, A.; Sartori, K.; White, C. I.; Sicard, A.; Rosa, S.

10.1101/2024.02.15.580253 — plant biology — Posted on 2024-02-19

1881 Dynamic Dark Root Chamber: Advancing non-invasive phenotyping of roots kept in darkness using infrared imaging

Pree, S.; Kashkan, I.; Retzer, K.

10.1101/2024.02.16.580252 — plant biology — Posted on 2024-02-19

1882 Transpiration efficiency variations in the pearl millet reference collection PMiGAP

Gregoire, L.; Kholova, J.; Srivastava, R.; Hash, C. T.; Vigouroux, Y.; Vadez, V.

10.1101/2024.02.16.580642 — plant biology — Posted on 2024-02-19

1883 Transport properties of canonical PIN-FORMED proteins and the role of the loop domain in auxin transport

Janacek, D. P.; Kolb, M.; Schulz, L.; Mergner, J.; Kuster, B.; Glanc, M.; Friml, J.; ten Tusscher, K.; Schwechheimer, C.; Hammes, U. Z.

10.1101/2024.02.15.580428 — plant biology — Posted on 2024-02-19

1884 Arabidopsis thaliana RHAMNOSE 1 condensate formation drives UDP-rhamnose synthesis

Field, S.; Dorone, Y.; Dwyer, W. P.; Cox, J. A.; Raba, D.; Froehlich, J.; Blea, M.; Carmo, O. M. S.; Wallace, I. S.; Hastings, R.; Boeynaems, S.; Rhee, S. Y.

10.1101/2024.02.15.580454 — plant biology — Posted on 2024-02-19

1885 Multimodal CustOmics: A Unified and Interpretable Multi-Task Deep Learning Framework for Multimodal Integrative Data Analysis in Oncology

Benkirane, H.; Vakalopoulou, M.; Planchard, D.; Adam, J.; Olaussen, K.; Michiels, S.; Cournede, P.-H.

10.1101/2024.01.20.576363 — cancer biology — Posted on 2024-02-19

1886 Benchmarking computational tools for de novo motif discovery

Simonetti, L.; Ivarsson, Y.; Davey, N. E.

10.1101/2024.01.12.574168 — bioinformatics — Posted on 2024-02-19

1887 The ABA Receptor Antagonist Antabactin Restores Germination of Thermoinhibited Lettuce

Eckhardt, J.; Cutler, S.

10.1101/2024.02.16.580753 — plant biology — Posted on 2024-02-19

1888 Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics

Morin, A.; Chu, C.; Pavlidis, P.

10.1101/2024.02.15.580581 — bioinformatics — Posted on 2024-02-19

1889 Delay of innate immune responses following influenza B virus infection affects the development of robust antibody response in ferrets

Rowe, T.; Fletcher, A.; Richardson, R. A.; Lange, M.; Sautto, G. A.; Kirchenbaum, G. A.; Hatta, Y.; Jasso, G.; Wentworth, D. E.; Ross, T. M.

10.1101/2024.02.19.580935 — microbiology — Posted on 2024-02-19

1890 Enteral immunization with live bacteria reprograms innate immune cells and protects neonatal foals from pneumonia

da Silveira, B. P.; Kahn, S. K.; Legere, R. M.; Bray, J. M.; Cole-Pfeiffer, H. M.; Golding, M. C.; Cohen, N. D.; Bordin, A. I.

10.1101/2024.02.17.579919 — immunology — Posted on 2024-02-19

1891 Tissue-resident regulatory T cells exert dualistic anti-tumour and pro-repair function in the exocrine pancreas

Stockis, J.; Yip, T.; Raghunathan, S.; Garcia, C.; Lee, S.; Simpson, C.; Silvain, S.; Schuijs, M. J.; Araos, J.; Png, S.; Raddi, G.; Bricard, O.; So, T. Y.; Mack, S.; Papadopoulos, P.; Sawle, A.; Jodrell, D. I.; McKenzie, A. N. J.; Thaventhiran, J.; Clatworthy, M.; Biffi, G.; Saeb-Parsy, K.; Liston, A.; Halim, T. Y. F.

10.1101/2024.02.15.580302 — immunology — Posted on 2024-02-19

1892 Recurrent neural networks that learn multi-step visual routines with reinforcement learning

Mollard, S.; Wacongne, C.; Bohte, S.; Roelfsema, P.

10.1101/2023.07.03.547198 — neuroscience — Posted on 2024-02-19

1893 Body reconstruction and size estimation of plesiosaurs

Zhao, R. J.

10.1101/2024.02.15.578844 — paleontology — Posted on 2024-02-19

1894 Revealing 3D cancer tissue structures using holotomography and virtual hematoxylin and eosin staining via deep learning

park, J.; Shin, S.-J.; Kim, M.; kim, g.; cho, H.; ryu, d.; ahn, d.; heo, j. e.; min, h.-s.; Lee, K. S.; Park, Y.; Hwang, T. H.

10.1101/2023.12.04.569853 — cancer biology — Posted on 2024-02-19

1895 Microtubule polymerization tuned by macromolecular crowdant size and density

Basu, J.; Soni, A.; Athale, C. A.

10.1101/2024.02.02.578534 — biophysics — Posted on 2024-02-19

1896 Integrating single-cell multimodal epigenomic data using 1D-convolutional neural networks

Gao, C.; Welch, J. D.

10.1101/2024.02.16.580655 — bioinformatics — Posted on 2024-02-19

1897 Signaling pathway evaluation of leading ATRi, PARPi and CDK7i cancer compounds targeting the DNA Damage Response using Causal Inference

Truter, N.; Bergh, W.; van den Heever, M.; Horn, S.; Shaw, K.; Leggate, D.; Wilkie, N.; Singh, R.

10.1101/2024.02.15.580418 — bioinformatics — Posted on 2024-02-19

1898 Effects of phosphorylation on protein backbone dynamics and conformational preferences

Bickel, D.; Vranken, W. F.

10.1101/2024.02.15.580491 — bioinformatics — Posted on 2024-02-19

1899 Infusing structural assumptions into dimension reduction for single-cell RNA sequencing data to identify small gene sets

Hackenberg, M.; Brunn, N.; Vogel, T.; Binder, H.

10.1101/2024.02.15.580085 — bioinformatics — Posted on 2024-02-19

1900 Licensing and competition of stem cells at the niche combine to regulate tissue maintenance

Garcia-Tejera, R.; Amoyel, M.; Grima, R.; Schumacher, L.

10.1101/2024.02.15.580493 — developmental biology — Posted on 2024-02-19

1901 Addressing Artemisinin Resistance in Malaria Treatment: A Novel Ferrous ACT (FACT) Formulation

Wang, Y.; Tang, K.

10.1101/2024.02.15.579727 — cell biology — Posted on 2024-02-19

1902 Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson Syndrome and Toxic epidermal necrolysis.

Gibson, A.; Ram, R.; Gangula, R.; Li, Y.; Mukherjee, E.; Palubinsky, A. M.; Campbell, C. N.; Thorne, M.; Konvinse, K. C.; Choshi, P.; Deshpande, P.; Pedretti, S.; O'Neil, R. T.; Wanjalla, C. N.; Kalams, S. A.; Gaudieri, S.; Lehloenya, R. J.; Bailin, S. S.; Chopra, A.; Trubiano, J. A.; Peter, J. G.; Mallal, S. A.; Phillips, E. J.

10.1101/2023.11.26.568771 — immunology — Posted on 2024-02-19

1903 Visual information is broadcast among cortical areas in discrete channels

Yu, Y.; Stirman, J. N.; Dorsett, C. R.; Smith, S. L.

10.1101/469114 — neuroscience — Posted on 2024-02-19

1904 Neural basis of perceptual surface qualities: Evidence from EEG decoding

Orima, T.; Wakita, S.; Motoyoshi, I.

10.1101/2024.02.05.578885 — neuroscience — Posted on 2024-02-19

1905 Orthogonal neural representations support perceptual judgements of natural stimuli

Srinath, R.; Ni, A. M.; Marucci, C.; Cohen, M. R.; Brainard, D. H.

10.1101/2024.02.14.580134 — neuroscience — Posted on 2024-02-19

1906 A novel pyridoindole improves the recovery of residual hearing following cochlear implantation after a single preoperative application

Nieratschker, M.; Yildiz, E.; Gerlitz, M.; Bera, S.; Gadenstaetter, A. J.; Kramer, A.-M.; Kwiatkowska, M.; Mistrik, P.; Landegger, L. D.; Braun, S.; Schlingensiepen, R.; Honeder, C.; Arnoldner, C.; Rommelspacher, H.

10.1101/2024.02.14.580226 — neuroscience — Posted on 2024-02-19

1907 High-precision photoacoustic neural modulation uses a non-thermal mechanism

Chen, G.; Yu, F.; Shi, L.; Marar, C.; Du, Z.; Jia, D.; Cheng, J.-X.; Yang, C.

10.1101/2024.02.14.580331 — neuroscience — Posted on 2024-02-19

1908 Dynamics of striatal action selection and reinforcement learning

Lindsey, J.; Markowitz, J. E.; Datta, S. R.; Litwin-Kumar, A.

10.1101/2024.02.14.580408 — neuroscience — Posted on 2024-02-19

1909 Sensorimotor mechanisms selective to numerosity: evidence from individual differences

Anobile, G.; Petrizzo, I.; Paiardini, D.; Burr, D.; Cicchini, G. M.

10.1101/2023.10.04.560837 — neuroscience — Posted on 2024-02-19

1910 Transcriptomic Dissection of the AMF-Solanum melongena Interaction: Unveiling Molecular Secrets

Jha, S. S.; Songachan, L. S.

10.1101/2024.02.17.580814 — plant biology — Posted on 2024-02-19

1911 Phylochemical mapping of natural products onto the plant tree of life using text mining and large language models.

Busta, L.; Hall, D.; Johnson, B.; Schaut, M.; Hanson, C. M.; Gupta, A.; Gondrum, M.; Wang, Y.; Maeda, H.

10.1101/2024.02.16.580694 — plant biology — Posted on 2024-02-19

1912 General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension through HIF-2a/Notch4 Pathway

Liu, B.; Yi, D.; Xia, X.; Ramirez, K.; Zhao, H.; Cao, Y.; Dong, R.; Gao, A.; Ding, H.; Qiu, S.; Kalinichenko, V. V.; Fallon, M. B.; Dai, Z.

10.1101/2024.02.13.580227 — physiology — Posted on 2024-02-19

1913 Delineating the Effective Use of Self-Supervised Learning in Single-Cell Genomics

Richter, T.; Bahrami, M.; Xia, Y.; Fischer, D. S.; Theis, F. J.

10.1101/2024.02.16.580624 — bioinformatics — Posted on 2024-02-18

1914 Systematic characterization of protein structural features of alternative splicing isoforms using AlphaFold 2

Yang, Y.; Xie, Y.; Li, Z.; Diala, C.; Ali, M.; Li, R.; Xu, Y.; Wu, A.; Kim, P.; Hosseini, S.-R.; Bi, E.; Zhao, H.; Zheng, W. J.

10.1101/2024.01.30.578053 — bioinformatics — Posted on 2024-02-19

1915 regLM: Designing realistic regulatory DNA with autoregressive language models

Lal, A.; Garfield, D.; Biancalani, T.; Eraslan, G.

10.1101/2024.02.14.580373 — genomics — Posted on 2024-02-19

1916 Minimal determinants for lifelong antiviral antibody responses in BALB/c mice from a single exposure to virus-like immunogens at low doses

Wholey, W.-Y.; Meyer, A. R.; Yoda, S.-T.; Chackerian, B.; Zikherman, J.; Cheng, W.

10.1101/2023.02.20.529089 — immunology — Posted on 2024-02-19

1917 Slc35a2 mosaic knockout impacts cortical development, dendritic arborisation, and neuronal firing in the developing brain

Spyrou, J.; Aung, K. P.; Vanyai, H.; Leventer, R. J.; Maljevic, S.; Lockhart, P. J.; Howell, K. B.; Reid, C. A.

10.1101/2024.02.18.580216 — neuroscience — Posted on 2024-02-18

1918 Mice lacking Astn2 have ASD-like behaviors and altered cerebellar circuit properties

Hanzel, M.; Fernando, K.; Maloney, S. E.; Gong, S.; Mätlik, K.; Zhao, J.; Pasolli, H. A.; Heissel, S.; Dougherty, J. D.; Hull, C.; Hatten, M. E.

10.1101/2024.02.18.580354 — neuroscience — Posted on 2024-02-18

1919 Postweaning development influences endogenous VPAC1 modulation of LTP induced by theta-burst stimulation: a link to maturation of the hippocampal GABAergic system?

Gil, M.; Caulino-Rocha, A.; Bento, M.; Rodrigues, N. C.; Silva-Cruz, A.; Ribeiro, J. A.; Cunha-reis, D.

10.1101/2024.02.18.580862 — neuroscience — Posted on 2024-02-19

1920 Prenatal Stress Alters Transcription of NMDA-Type Glutamate Receptors in the Hippocampus.

Buck, T. G.; Sodhi, M.

10.1101/2024.02.18.580903 — pharmacology and toxicology — Posted on 2024-02-18

1921 Transgenesis enables mapping of segmental ganglia in the leech Helobdella austinensis

Kuo, D.-H.; Szczupak, L.; Weisblat, D.; Portiansky, E.; Winchell, C.; Lee, J.-R.; Tsai, F.-Y.

10.1101/2024.02.14.580271 — zoology — Posted on 2024-02-18

1922 Hindlimb kinematics, kinetics, and muscle dynamics during sit-to-stand and sit-to-walk transitions in emus (Dromaius novaehollandiae)

LIn, Y.; Rankin, J. W.; Lamas, L. P.; Moazen, M.; Hutchinson, J. R.

10.1101/2024.02.14.580291 — zoology — Posted on 2024-02-18

1923 Division of labour underlies efficient colony defence in a clonal ant

Li, Z.; Wang, Q.; Knebel, D.; Veit, D.; Ulrich, Y.

10.1101/2024.02.16.580644 — animal behavior and cognition — Posted on 2024-02-18

1924 A chloroplast cell-free system for measuring ribosome binding site strengths

Clark, L.; Voigt, C.; Jewett, M. C.

10.1101/2024.02.17.580832 — synthetic biology — Posted on 2024-02-18

1925 Adaptive diversification through structural variation in barley

Jayakodi, M.; Lu, Q.; Pidon, H.; Rabanus-Wallace, M. T.; Bayer, M.; Lux, T.; Guo, Y.; Jaegle, B.; Badea, A.; Bekele, W.; Brar, G.; Braune, K.; Bunk, B.; Chalmers, K.; Chapman, B.; Jorgensen, M. E.; Feng, J.-W.; Feser, M.; Fiebig, A.; Gundlach, H.; Guo, W.; Haberer, G.; Hansson, M.; Himmelbach, A.; Hoffie, I.; Hoffie, R.; Hu, H.; Isobe, S.; Koenig, P.; Kale, S.; Kamal, N.; Keeble-Gagnere, G.; Keller, B.; Knauft, M.; Koppolu, R.; Krattinger, S.; Kumlehn, J.; Langridge, P.; Li, C.; Marone, M.; Maurer, A.; Mayer, K.; Melzer, M.; Muehlbauer, G.; Murozuka, E.; Padmarasu, S.; Perovic, D.; Pillen, K.;

10.1101/2024.02.14.580266 — plant biology — Posted on 2024-02-18

1926 Scale Cortisol Modulation in Cultured Nile Tilapia (Oreochromis niloticus): Deciphering the Intricate Role in Chronic Stress through Mitogen-Activated Protein Kinase Signaling Pathway Regulation

Mwaura, J. G.; Angienda, P. O.; Wekesa, C.; Namuyenga, E. T.; Ogutu, P.; Okoth, P.

10.1101/2024.02.14.580283 — physiology — Posted on 2024-02-18

1927 Effect of Light and Water Agitation on Hatching Processes in Clown Anemonefish Amphiprion ocellaris

Yamanaka, S.; Kawaguchi, M.; Yasumasu, S.; Sato, K.; Kinoshita, M.

10.1101/2024.02.14.580270 — physiology — Posted on 2024-02-18

1928 The freeze-avoiding mountain pine beetle (Dendroctonus ponderosae) survives prolonged exposure to stressful cold by mitigating ionoregulatory collapse

Andersen, M. K.; Roe, A. D.; Liu, A.; Musso, A. E.; Fudlosid, S.; Haider, F.; Evenden, M. L.; MacMillan, H. A.

10.1101/2024.02.14.580279 — physiology — Posted on 2024-02-18

1929 Molecular response to multiple trace-element contamination of the European sardine

Beauvieux, A.; Fromentin, J.-M.; Saraux, C.; Romero, D.; Couffin, N.; Brown, A.; Metral, L.; Bertile, F.; Schull, Q.

10.1101/2024.02.16.580673 — physiology — Posted on 2024-02-18

1930 Quantifying forms and functions of intestinal bile acid pools in mice

Sudo, K.; Delmas-Eliason, A.; Soucy, S.; Barrack, K. E.; Liu, J.; Balasubramanian, A.; Shu, C. J.; James, M.; Hegner, C. L.; Dionne, H. D.; Rodriguez-Palacios, A.; Krause, H.; O'Toole, G. A.; Karpen, S. J.; Dawson, P. A.; Schultz, D.; Sundrud, M. S.

10.1101/2024.02.16.580658 — physiology — Posted on 2024-02-18

1931 Fingerprint localisation for fine-scale wildlife tracking using automated radio telemetry

Tyson, C.; Fragueira, R.; Sansano-Sansano, E.; Yu, H.; Naguib, M.

10.1101/2024.02.15.580447 — animal behavior and cognition — Posted on 2024-02-18

1932 Automated 3D analysis of social head-gaze behaviors in freely moving marmosets

Xing, F.; Sheffield, A. G.; Jadi, M. P.; Chang, S. W. C.; Nandy, A. S.

10.1101/2024.02.16.580693 — animal behavior and cognition — Posted on 2024-02-18

1933 Limited parallelism in genetic adaptation to brackish water bodies in European sprat and Atlantic herring

Pettersson, M. E.; Quintela, M.; Besnier, F.; Deng, Q.; Berg, F.; Kvamme, C.; Bekkevold, D.; Mosbech, M.-B.; Bunikis, I.; Lille-Langoey, R.; Leonori, I.; Wallberg, A.; Glover, K. A.; Andersson, L.

10.1101/2024.02.16.580647 — genomics — Posted on 2024-02-18

1934 Long-term dynamics of adaptation to a warming environment is dependent on historical background

Antunes, M. A.; Grandela, A.; Matos, M.; Simoes, P.

10.1101/2024.02.15.580572 — evolutionary biology — Posted on 2024-02-18

1935 Functional brain imaging predicts population-level visits to urban spaces

Kaur, A.; Rodrigues, A. L.; Hoogstraten, S.; Blanco-Mora, D. A.; Miranda, B.; Morgado, P.; Meshi, D.

10.1101/2024.02.16.580650 — neuroscience — Posted on 2024-02-18

1936 Fluorescence Shadow Imaging of Hypsibius exemplaris Reveals Morphological Differences Between Sucrose- and CaCl2-Induced Osmobiotes

Flinn, B. B.; O'Dell, H. M.; Joseph, K. M.; Smythers, A. L.; Neff, D. P.; Hicks, L. M.; Norton, M. L.; Kolling, D. R.

10.1101/2024.02.14.580268 — physiology — Posted on 2024-02-18

1937 Marsilea: An intuitive generalized visualization paradigm for complex datasets

Zheng, Y.; Zheng, Z.; Rendeiro, A. F.; Cheung, E.

10.1101/2024.02.14.580236 — bioinformatics — Posted on 2024-02-18

1938 High-frequency amplitude-modulated sinusoidal stimulation induces desynchronized yet controllable neural firing

Barra, B.; Kumar, R.; Gopinath, C.; Mirzakhalili, E.; Lempka, S. F.; Gaunt, R. A.; Fisher, L. E.

10.1101/2024.02.14.580219 — bioengineering — Posted on 2024-02-18

1939 Molecular basis of inhibition of the amino acid transporter B0AT1 (SLC6A19)

Xu, J.; Hu, Z.; Dai, L.; Yadav, A.; Jiang, Y.; Broer, A.; Gardiner, M.; McLeod, M.; Yan, R.; Broer, S.

10.1101/2024.02.18.580905 — biochemistry — Posted on 2024-02-18

1940 Structural and biochemical analysis of a B12 super-binder

Martinez-Felices, J. M.; Whittaker, J. J.; Slotboom, D.; Guskov, A.

10.1101/2024.02.16.580637 — biochemistry — Posted on 2024-02-18

1941 regLM: Designing realistic regulatory DNA with autoregressive language models

Lal, A.; Garfield, D.; Biancalani, T.; Eraslan, G.

10.1101/2024.02.14.580373 — genomics — Posted on 2024-02-18

1942 The Cryptic Bacterial Microproteome

Fesenko, I.; Sahakyan, H.; Shabalina, S. A.; Koonin, E. V.

10.1101/2024.02.17.580829 — genomics — Posted on 2024-02-18

1943 Selection for later flowering time in an orchid through frost damage and pollinator activity

Wartmann, B.; Ruth, B.; Brigitte, G.-K.; Klaus, H.; Merz, E.; Luder, J.; Peter, B.; Reutlinger, M.; Richter, T.; Senn, H.; Ulrich, T.; Waldeck, B.; Wartmann, C.; Wuest, R.; Wuest, W.; Rusman, Q.; Schiestl, F. P.

10.1101/2024.02.14.580274 — evolutionary biology — Posted on 2024-02-18

1944 Indicators of a data-deficient taxa: combining bird and environmental data enhances predictive accuracy of wild bee richness

Rousseau, J. S.; Johnston, A.; Rodewald, A. D.

10.1101/2024.02.14.580016 — ecology — Posted on 2024-02-18

1945 Molecular characterization and culture optimization of marine copepod Oithona dissimilis (Landberg, 1940) from Nagore coastal waters, Southern India

PILIYAN, R. P.; Perumal, S.; Barathan, B. P.; Meril, D.; Ragothaman, P.; Shanmugam, G.; Pachippan, P.

10.1101/2024.02.14.580272 — ecology — Posted on 2024-02-18

1946 Workflow enhancement of TurboID-mediated proximity labeling for SPY signaling network mapping

Grismer, T. S.; Karundasa, S. S.; Shrestha, R.; Byun, D.; Ni, W.; Reyes, A. V.; xu, s.

10.1101/2024.02.17.580820 — molecular biology — Posted on 2024-02-18

1947 Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.

Chaumeau, V.; Wasisakun, P.; Watson, J. A.; Oo, T.; Aryalamloed, S.; Sue, M. P.; Htoo, G. N.; Tha, N. M.; Archusuksan, L.; Sawasdichai, S.; Gornsawun, G.; Mehra, S.; White, N. J.; Nosten, F.

10.1101/2024.02.18.580875 — microbiology — Posted on 2024-02-18

1948 The first discovery of SFTSV in the Centre of Metropolitan Beijing, China

Zheng, A.; Yuan, F.; Zhu, L.; Tian, D.; Xia, M.; Zheng, M.; Zhang, Q.; Zhang, T.; Zhang, X.

10.1101/2024.02.18.580844 — microbiology — Posted on 2024-02-18

1949 Pneumocystis murina Promotes Inflammasome Formation and NETosis during Pneumocystis Pneumonia

Sayson, S. G.; Ashbaugh, A.; Porollo, A.; Cushion, M. T.

10.1101/2024.02.16.580773 — immunology — Posted on 2024-02-18

1950 Dual Targeting of STING and PI3Kγ Eliminates Regulatory B Cells to Overcome STING Resistance for Pancreatic Cancer Immunotherapy

LI, C.; Mao, S.; Zhao, H.; He, M.; Wang, M.; Liu, Z.; Wen, H.; Yu, Z.; Wen, B.; Djibo, M.; Tao, J.; Bu, Y.; Gao, W.; Sun, D.

10.1101/2024.02.14.580378 — pharmacology and toxicology — Posted on 2024-02-18

1951 Synthesis, Structure and Anticancer Activity of a Dinuclear Organoplatinum(IV) Complex Stabilized by Adenine

O'Brien, A. M.; Howard, W. A.; Wheeler, K. A.

10.1101/2024.02.14.580361 — cancer biology — Posted on 2024-02-18

1952 Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells

10.1101/2024.02.14.580332 — cancer biology — Posted on 2024-02-18

1953 High-resolution single particle imaging at 100-200 keV with the Gatan Alpine direct electron detector.

Chan, L. M.; Courteau, B. J.; Maker, A.; Wu, M.; Basanta, B.; Mehmood, H.; Bulkley, D.; Joyce, D.; Lee, B. C.; Mick, S.; Gulati, S.; Lander, G. C.; Verba, K. A.

10.1101/2024.02.14.580363 — biophysics — Posted on 2024-02-18

1954 Dynamics of aqueous suspension of short Hyaluronic acid chains near DPPC bilayer

PAUL, A.; Chakrabarti, J.

10.1101/2024.02.14.580078 — biophysics — Posted on 2024-02-18

1955 Repurposing approved protein kinase inhibitors as potent anti-leishmanials targeting Leishmania MAP kinases

Bhattacharjee, A.; Bagchi, A.; Sarkar, S.; Bawali, S.; Bhattacharya, A.; BISWAS, A.

10.1101/2024.02.16.580710 — bioinformatics — Posted on 2024-02-18

1956 Long Read Sequencing reveals transgene concatemerization and backbone integration following AAV-driven electroporation of CRISPR RNP complexes in mouse zygotes

Luqman, M. W.; Jenjaroenpun, P.; Spathos, J.; Shingte, N.; Cummins, M.; Nimsamer, P.; Ittner, L. M.; Wongsurawat, T.; Delerue, F.

10.1101/2024.02.18.580906 — bioengineering — Posted on 2024-02-18

1957 Back-pocket optimization of 2-aminopyrimidine-based macrocycles leads to potent dual EPHA2/GAK kinase inhibitors with antiviral activity

Gerninghaus, J.; Zhubi, R.; Kraemer, A.; Karim, M.; Tran, D. H. N.; Joerger, A. C.; Schreiber, C.; Berger, L. M.; Berger, B. T.; Ehret, T. A. L.; Elson, L.; Lenz, C.; Saxena, K.; Mueller, S.; Einav, S.; Knapp, S.; Hanke, T.

10.1101/2024.02.18.580805 — biochemistry — Posted on 2024-02-18

1958 The evolution of 5'UTR length was shaped by natural selection for its functional impact on gene expression

Zhan, Y.; Hu, Z.; Lu, Z.; Lin, Z.

10.1101/2024.02.17.580833 — genomics — Posted on 2024-02-18

1959 DEAD-box ATPase Dbp2 mediates mRNA release after 3'-end formation

Aydin, E.; Boehme, J.; Keil, B.; Schreiner, S.; Zunar, B.; Glatter, T.; Kilchert, C.

10.1101/2024.02.17.580811 — molecular biology — Posted on 2024-02-18

1960 Fertilization by short-term stored sperm alters DNA methylation patterns in common carp (Cyprinus carpio) embryos at single-base resolution

Cheng, Y.; Zhang, S.; Nayak, R.; Vechtova, P.; Schumacher, F.; Linhartova, P.; Gazo, I.; Linhartova, Z.; Waghmare, S. G.; Kleuser, B.; Dey, A.; Rodinova, V.; Rodina, M.; Sterba, J.; Alavi, S. M. H.; Labbe, C.; Linhart, O.

10.1101/2024.02.18.580899 — molecular biology — Posted on 2024-02-18

1961 Fecal Virome Transplantation (FVT) from healthy humans remodels the gut bacteriome and virome and reduces metabolic syndrome in mice

Cervantes-Echeverria, M. J.; Jimenez-Rico, M. A.; Manzo, R.; Hernandez-Reyna, A.; Cornejo-Granados, F.; Sanchez-Lopez, F.; Salazar-Leon, J.; Pedraza-Alva, G.; Perez-Martinez, L.; Ochoa-Leyva, A.

10.1101/2024.02.17.580809 — microbiology — Posted on 2024-02-18

1962 Single molecule imaging of the central dogma reveals myosin-2A gene expression is regulated by contextual translational buffering

Wiggan, O.; Stasevich, T. J.

10.1101/2024.02.11.579797 — cell biology — Posted on 2024-02-18

1963 The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans

Xue, P.; Sanchez-Leon, E.; Hu, G.; Lee, C.; Black, B.; Brisland, A.; Li, H.; Jung, W. H.; Kronstad, J. W.

10.1101/2024.02.15.580540 — microbiology — Posted on 2024-02-18

1964 Micro-Scale Control of Oligodendrocyte Morphology and Myelination by the Intellectual Disability-Linked Protein Acyltransferase ZDHHC9

Jeong, H.-K.; Gonzalez-Fernandez, E.; Crawley, I.; Hwang, J.; Martin, D. D. O.; Bamji, S. X.; KIM, J.-I.; Kang, S.-H.; Thomas, G.

10.1101/2023.09.19.558291 — neuroscience — Posted on 2024-02-18

1965 Augmented Reality and Cross-Device Interaction for Seamless Integration of Physical and Digital Scientific Papers

Miah, M. O.; Kong, J.

10.1101/2024.02.05.578116 — scientific communication and education — Posted on 2024-02-18

1966 After wounding, a G-protein coupled receptor promotes the restoration of tension in epithelial cells

Han, I.; Hua, J.; White, J. S.; O'Connor, J. T.; Nassar, L. S.; Tro, K. J.; Page-McCaw, A.; Hutson, M. S.

10.1101/2023.05.31.543122 — biophysics — Posted on 2024-02-18

1967 The Backpack Quotient Filter: a dynamic and space-efficient data structure for querying k-mers with abundance.

Levallois, V.; Andreace, F.; Le Gal, B.; Dufresne, Y.; Peterlongo, P.

10.1101/2024.02.15.580441 — bioinformatics — Posted on 2024-02-18

1968 A biodegradable microgrooved and tissue mechanocompatible citrate-based scaffold improves bladder tissue regeneration

Goedegebuure, M.; Bury, M.; Wang, X.; San Felice, P.; Cammarata, F.; Wang, L.; Sharma, T.; Rajinikanth, N.; Karra, V.; Siddha, V.; Sharma, A.; Ameer, G.

10.1101/2024.02.15.580554 — bioengineering — Posted on 2024-02-18

1969 Discovery and characterization of chromosomal inversions in the arboviral vector mosquito Aedes aegypti

Liang, J.; Rose, N. H.; Brusentsov, I. I.; Lukyanchikova, V.; Karagodin, D. A.; Feng, Y.; Yurchenko, A. A.; Sylla, M.; Lutomiah, J.; Badolo, A.; Aribodor, O. B.; Ayala, D.; Acosta, C. G.; Alto, B. W.; Ahmad, N. W.; Tu, Z.; Gloria-Soria, A.; Black, W. C.; Powell, J.; Sharakhov, I. V.; McBride, C. S.; Sharakhova, M. V.

10.1101/2024.02.16.580682 — evolutionary biology — Posted on 2024-02-18

1970 Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid and IL4-Driven Macrophage Programming

Deochand, D. K.; Dacic, M.; Bale, M. J.; Daman, A. W.; Josefowicz, S. Z.; Oliver, D.; Chinenov, Y.; Rogatsky, I.

10.1101/2024.02.16.580560 — immunology — Posted on 2024-02-18

1971 MRI economics: Balancing sample size and scan duration in brain wide association studies

Ooi, L. Q. R.; Orban, C.; Nichols, T.; Zhang, S.; Tan, T. W. K.; Kong, R.; Marek, S.; Dosenbach, N. U. F.; Laumann, T. O.; Gordon, E. M.; Zhou, J. H.; Bzdok, D.; Eickhoff, S. B.; Holmes, A. J.; Yeo, B. T. T.

10.1101/2024.02.16.580448 — neuroscience — Posted on 2024-02-18

1972 AlphaFind: Discover structure similarity across the entire known proteome

Prochazka, D.; Slaninakova, T.; Olha, J.; Rosinec, A.; Gresova, K.; Janosova, M.; Cillik, J.; Porubska, J.; Svobodova, R.; Dohnal, V.; Antol, M.

10.1101/2024.02.15.580465 — bioinformatics — Posted on 2024-02-18

1973 InSilicoSeq 2.0: Simulating realistic amplicon-based sequence reads

Lelieveld, S. H.; Maas, T.; Duk, T. C. X.; Gourle, H.; van den Ham, H.-J.

10.1101/2024.02.16.580469 — bioinformatics — Posted on 2024-02-18

1974 Tinted de Bruijn Graphs for efficient read extraction from sequencing datasets

Vandamme, L.; Cazaux, B.; Limasset, A.

10.1101/2024.02.15.580442 — bioinformatics — Posted on 2024-02-18

1975 Genome announcement and analysis of five new mycobacteriophages belonging to the F, G, K, and P clusters

Arora, R.; Das, R.; Nadar, K.; Bajpai, U.

10.1101/2024.02.15.580488 — genomics — Posted on 2024-02-18

1976 Genome sequences of three Konjac mosaic virus (KoMV) variants

Breit, T. M.; de Leeuw, W. C.; van Olst, M. F.; Ensink, W. A.; van Leeuwen, S. M.; Jonker, M. J.; Dekker, R. J.

10.1101/2024.02.16.579633 — genomics — Posted on 2024-02-18

1977 Mutations compensating for cell polarity defects change the gene-fitness relationship on a genome-wide scale

Kingma, E.; Laan, L.

10.1101/2024.02.15.580535 — evolutionary biology — Posted on 2024-02-18

1978 Integrating environmental and ecological monitoring with seaweed farming

Berger, C.; Marshall, B.; Papazova, P.; Evans, F.; Williams, C.

10.1101/2024.02.15.580450 — ecology — Posted on 2024-02-18

1979 Inflammatory pain resolution by mouse serum-derived small extracellular vesicles

Lin, Z.; Luo, X.; Wickman, J. R.; Reddy, D.; Pande, R.; Tian, Y.; Triana, V.; Lee, J.; Furdui, C. M.; Pink, D.; Sacan, A.; Ajit, S. K.

10.1101/2024.02.16.578759 — neuroscience — Posted on 2024-02-18

1980 Tracking single cell evolution via clock-like chromatin accessibility

Xiao, Y.; Jin, W.; Ju, L.; Fu, J.; Wang, G.; Yu, M.; Chen, F.; Qian, K.; Wang, X.; Zhang, Y.

10.1101/2022.05.12.491736 — bioinformatics — Posted on 2024-02-18

1981 SVarp: pangenome-based structural variant discovery

Soylev, A.; Ebler, J.; Pani, S.; Rausch, T.; Korbel, J.; Marschall, T.

10.1101/2024.02.18.580171 — bioinformatics — Posted on 2024-02-18

1982 Positioning Genomic Features in Biomedical Knowledge Graphs using the Homo sapiens Chromosomal Location Ontology for GRCh38 (HSCLO38)

Mohseni Ahooyi, T.; Stear, B. J.; Taylor, D. M.

10.1101/2024.02.15.580505 — bioinformatics — Posted on 2024-02-18

1983 Myxomycetes have an allorecognition system that can only discriminate between intraspecies

Masui, M.; Yamamoto, P.; Kono, N.

10.1101/2024.02.15.580440 — animal behavior and cognition — Posted on 2024-02-18

1984 Combining single-gene-resistant and pyramided cultivars in agricultural landscape compromises the benefits of pyramiding in most, but not all, productions situations

ZAFFARONI, M.; Papaix, J.; Rimbaud, L.; Geffersa, A. G.; Rey, J.-F.; Fabre, F.

10.1101/2024.02.14.580232 — evolutionary biology — Posted on 2024-02-18

1985 Regression and Alignment for Functional Data and Network Topology

Tu, D.; Wrobel, J.; Satterthwaite, T. D.; Goldsmith, J.; Gur, R. C.; Gur, R. E.; Gertheiss, J.; Bassett, D. S.; Shinohara, R. T.

10.1101/2023.07.13.548836 — neuroscience — Posted on 2024-02-18

1986 Development of a Marmoset Apparatus for Automated Pulling (MarmoAAP) to Study Cooperative Behaviors

Meisner, O. C.; Fagan, N. A.; Greenwood, J.; Jadi, M.; Nandy, A. S.; Chang, S. W. C.

10.1101/2024.02.16.579531 — neuroscience — Posted on 2024-02-18

1987 Atox1-Cyclin D1 Loop Activity is Critical for Survival of Tumor Cells with Inactivated TP53

Kuchur, O. A.; Pogodaeva, S. S.; Shcherbakova, A. V.; Tsymbal, S. A.

10.1101/2024.02.14.580254 — cancer biology — Posted on 2024-02-18

1988 QInfoMating: Sexual Selection and Assortative Mating Estimation Software

Carvajal-Rodriguez, A.

10.1101/2023.09.06.556585 — evolutionary biology — Posted on 2024-02-18

1989 Filamin A mediates embryonical palatal fusion by linking mechanotransduction with β-Catenin/Smad2

Wang, Z.; Hayano, S.; Weng, Y.; Mu, X.; Ono, M.; Pina, J. O.; D'Souza, R. N.; Yamashiro, T.; Oohashi, T.; Kamioka, H.

10.1101/2024.02.16.580664 — developmental biology — Posted on 2024-02-18

1990 Structural insights into IMP2 dimerization and RNA binding

Zorc, S.; Munoz-Tello, P.; O'Leary, T.; Yu, X.; Nag, M.; Hansel-Harris, A.; Forli, S.; Griffin, P. R.; Kojetin, D. J.; Roy, R. N.; Janiszewska, M.

10.1101/2024.02.16.580656 — molecular biology — Posted on 2024-02-18

1991 The interplay between electron transport chain function and iron regulatory factors influences melanin formation in Cryptococcus neoformans

Xue, P.; Sanchez-Leon, E.; Hu, G.; Lee, C.; Black, B.; Brisland, A.; Li, H.; Jung, W. H.; Kronstad, J. W.

10.1101/2024.02.15.580540 — microbiology — Posted on 2024-02-18

1992 Identification of novel Bromodomain inhibitors of Trypanosoma cruzi Bromodomain Factor 2 (TcBDF2) using a fluorescence polarization-base high-throughput assay

Serra, E. C.; Tavernelli, L.; Alonso, V. L.; Pena, I.; Rodriguez Araya, E.; Manarin, R.; Cantizani, J.; Martin, J.; Salamanca, J.; Bamborough, P.; Calderon, F.; Gabarro, R.

10.1101/2024.02.16.580721 — microbiology — Posted on 2024-02-18

1993 mgPGPT: Metagenomic analysis of plant growth-promoting traits

Patz, S.; Rauh, M.; Gautam, A.; Huson, D. H.

10.1101/2024.02.17.580828 — bioinformatics — Posted on 2024-02-18

1994 TANK binding kinase 1 promotes BACH1 degradation through both phosphorylation-dependent and -independent mechanisms without relying on heme and FBXO22

Liu, L.; Matsumoto, M.; Matsui-Watanabe, M.; Nakagawa, T.; Nagasawa, Y.; Pang, J.; Callens, B. K. K.; Muto, A.; Ochiai, K.; Takekawa, H.; Alam, M.; Nishizawa, H.; Shirouzu, M.; Shima, H.; Nakayama, K.; Igarashi, K.

10.1101/2024.02.15.580587 — biochemistry — Posted on 2024-02-18

1995 Massive-scale single-cell chromatin accessibility sequencing using combinatorial fluidic indexing

Zhang, X.; Marand, A. P.; Yan, H.; Schmitz, R. J.

10.1101/2023.09.17.558155 — genomics — Posted on 2024-02-18

1996 PTBP2 promotes cell survival and autophagy in Chronic Myeloid Leukemia by stabilizing BNIP3

Barik, B.; Lama, S.; IS, S.; Chanda, S.; Biswas, S.; Biswas, G.; Mohapatra, S.; chakraborty, S.

10.1101/2024.01.26.577177 — cancer biology — Posted on 2024-02-18

1997 Impaired response to mismatch novelty in the Li2+-pilocarpine rat model of TLE: correlation with hippocampal monoaminergic inputs

Nascimento, C.; Guerreiro-Pinto, V.; Pawlak, S.; Caulino-Rocha, A.; Amat-Garcia, L.; Cunha-Reis, D.

10.1101/2024.02.07.579299 — neuroscience — Posted on 2024-02-18

1998 Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha

Yelina, N. E.; Frangedakis, E.; Wang, Z.; Schreier, T. B.; Rever, J.; Tomaselli, M.; Forestier, E.; Billakurthi, K.; Ren, S.; Bai, Y.; Stewart-Wood, J.; Haseloff, J.; Zhong, S.; Hibberd, J. M.

10.1101/2023.01.23.525199 — plant biology — Posted on 2024-02-18

1999 Androgen deprivation triggers a cytokine signaling switch to induce immune suppression and prostate cancer recurrence

Sha, K.; Zhang, R.; Maolake, A.; Singh, S.; Chatta, G.; Eng, K. H.; Nastiuk, K. L.; Krolewski, J. J.

10.1101/2023.12.01.569685 — cancer biology — Posted on 2024-02-18

2000 A note on predator-prey dynamics in radiocarbon datasets

Marom, N.; Wolkowski, U.

10.1101/2023.11.12.566733 — ecology — Posted on 2024-02-18

2001 Revealing principles of autonomous thermal soaring in windy conditions using vulture-inspired deep reinforcement-learning

Flato, Y.; Harel, R.; Tamar, A.; Nathan, R.; Beatus, T.

10.1101/2023.09.18.558216 — animal behavior and cognition — Posted on 2024-02-18

2002 Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo

Ichimura, T.; Kakizuka, T.; Sato, Y.; Itano, K.; Seiriki, K.; Hashimoto, H.; Itoga, H.; Onami, S.; Nagai, T.

10.1101/2023.08.21.553997 — developmental biology — Posted on 2024-02-18

2003 Adaptation of human cell populations to different levels of centriole amplification involves a two-step response

Dias Louro, M. A.; Peneda, C.; Bank, C.; Bettencourt Dias, M.

10.1101/2024.02.15.580424 — cell biology — Posted on 2024-02-17

2004 Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

Smirnova, A. M.; Hronova, V.; Mohammad, M. P.; Herrmannova, A.; Gunisova, S.; Petrackova, D.; Halada, P.; Coufal, S.; Swirski, M.; Rendelman, J.; Jendruchova, K.; Hatzoglou, M.; Beznoskova, P.; Vogel, C.; Valasek, L. S.

10.1101/2023.07.12.548609 — molecular biology — Posted on 2024-02-18

2005 The De Bruijn Graph Sequence Mapping Problem with Changes in the Graph

B. Rocha, L.; Adi, S. S.; Araujo, E.

10.1101/2024.02.15.580401 — bioinformatics — Posted on 2024-02-17

2006 Nm-Nano: A Machine Learning Framework for Transcriptome-Wide Single Molecule Mapping of 2{acute}-O-Methylation (Nm) Sites in Nanopore Direct RNA Sequencing Datasets

Salem, D. H.; Ariyur, A.; Daulatabad, S. V.; Mir, Q.; Janga, S. C.

10.1101/2022.01.03.473214 — bioinformatics — Posted on 2024-02-17

2007 Nanopore-based consensus sequencing enables accurate multimodal tumor cell-free DNA profiling

Chen, L.-T.; Jager, M.; Rebergen, D.; Brink, G. J.; van den Ende, T.; Vanderlinden, W.; Kolbeck, P.; Pages-Gallego, M.; van der Pol, Y.; Besselink, N.; Moldovan, N.; Hami, N.; Kloosterman, W.; van Laarhoven, H.; Mouliere, F.; Zweemer, R.; Lipfert, J.; Derks, S.; Marcozzi, A.; de Ridder, J.

10.1101/2024.02.16.580684 — genomics — Posted on 2024-02-17

2008 MagIC-Cryo-EM: Structural determination on magnetic beads for scarce macromolecules in heterogeneous samples

Arimura, Y.; Konishi, H. A.; Funabiki, H.

10.1101/2024.01.21.576499 — molecular biology — Posted on 2024-02-17

2009 Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation

Witt, L.; Greenfield, K.; Knoop, K.

10.1101/2023.10.02.560561 — immunology — Posted on 2024-02-17

2010 Tobacco Images Choice and Its Association with Craving and Dependence in Cigarette Smokers

Solinas, M.; Chauvet, C.; Lafay-Chebassier, C.; Vanderkam, P.; Barillot, L.; Moeller, S. J.; Goldstein, R. Z.; Noel, X.; Jaafari, N.; Chatard, A.

10.1101/2023.08.30.555462 — neuroscience — Posted on 2024-02-17

2011 Exploring Nonlinear Dynamics In Brain Functionality Through Phase Portraits And Fuzzy Recurrence Plots

Li, Q.; Calhoun, V.; Pham, T.; Iraji, A.

10.1101/2023.07.06.547922 — neuroscience — Posted on 2024-02-17

2012 Depression Attenuates Caudate and Dorsolateral Prefrontal Cortex Alpha and Beta Power Response to Reward

Qian, H.; Johnson, G. W.; Hughes, N. C.; Paulo, D. L.; Zhao, Z.; Subramanian, D.; Dhima, K.; Bick, S. K.

10.1101/2024.02.05.578848 — neuroscience — Posted on 2024-02-17

2013 Spatiotemporal Changes in Netrin/Dscam1 Signaling Dictate Axonal Projection Direction in Drosophila Small Ventral Lateral Clock Neurons

Liu, J.; Wang, Y.; Han, J.; Tian, Y.

10.1101/2024.02.15.580478 — neuroscience — Posted on 2024-02-17

2014 Monoclonal antibody chP3R99 reduces subendothelial retention of atherogenic lipoproteins in Insulin-Resistant rats: Acute treatment versus long-term protection as an idiotypic vaccine for atherosclerosis

Soto, Y.; Hernandez, A.; Sarduy, R.; Brito, V.; Marleau, S.; Vine, D.; Vazquez, A. M.; Proctor, S. D.

10.1101/2023.08.30.555546 — pathology — Posted on 2024-02-17

2015 A comprehensive evaluation of taxonomic classifiers in marine vertebrate eDNA studies

Bayer, P. E.; Bennett, A.; Nester, G.; Corrigan, S.; Raes, E. J.; McInnes, A. S.; Cooper, M.; Ayad, M. E.; McVey, P.; Kardailsky, A.; Pearce, J.; Fraser, M. W.; Goncalves, P.; Burnell, S.; Rauschert, S.

10.1101/2024.02.15.580601 — ecology — Posted on 2024-02-17

2016 Genes required for the formation of virulence-provoking bacterial sphingolipids

Olea-Ozuna, R. J.; Poggio, S.; Bergström, E.; Osorio, A.; ELUFISAN, T. O.; Padilla-Gomez, J.; Martinez-Aguilar, L.; Lopez-Lara, I. M.; Thomas-Oates, J.; Geiger, O.

10.1101/2024.02.16.580706 — microbiology — Posted on 2024-02-17

2017 Asgard archaea defense systems and their roles in the origin of immunity in eukaryotes

Leao, P.; Little, M. E.; Appler, K. E.; Sahaya, D.; Aguilar-Pine, E.; Currie, K.; Finkelstein, I. J.; De Anda, V.; Baker, B. J.

10.1101/2023.09.13.557551 — microbiology — Posted on 2024-02-17

2018 THE POSSIBILITY OF THE USE OF LEUKOCYTES IN WEAK BLOOD GROUP ANTIGENS DETECTION

Kravchun, P.; Leontyeva, F.; Povelichenko, O.; Dielievska, V.

10.1101/2024.02.13.580159 — immunology — Posted on 2024-02-17

2019 Highly efficient in vivo mutagenesis method based on the endonuclease and exonuclease activity of Bacillus alcalophilus RecJ (BaRecJ)

Shang, J.; Zhang, Y.; Xu, Z.; Sun, Z.; Zheng, M.; Zhang, S.

10.1101/2024.02.16.580766 — bioengineering — Posted on 2024-02-17

2020 Developing Hybrid Systems to Address O2 Uncoupling in Multi-Component Rieske Oxygenases

Runda, M. E.; Miao, H.; de Kok, N. A. W.; Schmidt, S.

10.1101/2024.02.16.580709 — biochemistry — Posted on 2024-02-17

2021 Architecture of the spinach plastid-encoded RNA polymerase

Wang, T.; Wang, G.; Fang, Y.; Zhang, Y.; Peng, W.; Zhou, Y.; Zhang, A.; Yu, L.-J.; Lu, C.

10.1101/2024.02.16.580782 — biochemistry — Posted on 2024-02-17

2022 A new chromosome-level genome assembly and annotation of Cryptosporidium meleagridis

Penumarthi, L. R.; de Paula Baptista, R. C.; Beaudry, M. S.; Glenn, T.; Kissinger, J. C.

10.1101/2024.02.16.580748 — genomics — Posted on 2024-02-17

2023 CYP1A1/1A2 enzymes mediate glucose homeostasis and insulin secretion in mice in a sex-specific manner

Ching, M. E. A.; Hoyeck, M. P.; Basu, L.; Merhi, R.; van Zyl, E.; Crawley, A. M.; Bruin, J. E.

10.1101/2024.02.16.580670 — molecular biology — Posted on 2024-02-17

2024 The budding yeast Fkh1 Forkhead associated (FHA) domain promotes the G1-chromatin status and activity of chromosomal DNA replication origins

Hoggard, T.; Chacin, E.; Hollatz, A. J.; Kurat, C. F.; Fox, C. A.

10.1101/2024.02.16.580712 — molecular biology — Posted on 2024-02-17

2025 Gammaherpesvirus infection alters transfer RNA splicing and triggers tRNA cleavage

Manning, A. C.; Bashir, M. M.; Jimenez, A. C.; Upton, H. E.; Collins, K.; Lowe, T. M.; Tucker, J. M.

10.1101/2024.02.16.580780 — microbiology — Posted on 2024-02-17

2026 Time of arrival during disease progression and humidity additively influence Salmonella enterica colonization of lettuce

Dixon, M. H.; Nellore, D.; Zaacks, S. C.; Barak, J. D.

10.1101/2024.02.16.580743 — microbiology — Posted on 2024-02-17

2027 Aspergillus dsRNA virus drives fungal fitness and pathogenicity in the mammalian host

Shlezinger, N.; Lerer, V.; Rocha, M.; Adeoye, J.; Hayby, H.

10.1101/2024.02.16.580674 — microbiology — Posted on 2024-02-17

2028 Elucidating effects of single and multiple resistance mechanisms on bacterial response to meropenem by quantitative and systems pharmacology modeling and population genomics

Fuhs, D. T.; Cortes-Lara, S.; Tait, J. R.; Rogers, K. E.; Lopez-Causape, C.; Lee, W. L.; Shackleford, D. M.; Nation, R. L.; Oliver, A.; Landersdorfer, C. B.

10.1101/2024.02.17.579784 — microbiology — Posted on 2024-02-17

2029 Using structure prediction of negative sense RNA virus nucleoproteins to assess evolutionary relationships

Sabsay, K.; te Velthuis, A. J. W.

10.1101/2024.02.16.580771 — microbiology — Posted on 2024-02-17

2030 Prevalence and preferred niche of small eukaryotes with mixotrophic potentials in the global ocean

Dong, K.; Wang, Y.; Zhang, W.; Li, Q.

10.1101/2024.02.17.580790 — microbiology — Posted on 2024-02-17

2031 A General Mechanism for the General Stress Response in Bacteria

Baral, R.; Ho, K.; Ramasamy, P. K.; Hopkins, J. B.; Watkins, M. B.; LaRussa, S.; Caban=Penix, S.; Calderone, L. A.; Bradshaw, N.

10.1101/2024.02.16.580724 — microbiology — Posted on 2024-02-17

2032 Expanding the phage galaxy: Isolation and characterization of five novel Streptomyces siphoviruses Ankus, Byblos, DekoNeimoidia, Mandalore, and Naboo

Erdrich, S.; Luthe, T.; Kever, L.; Badia Roige, B.; Arsova, B.; Davoudi, E.; Frunzke, J.

10.1101/2024.02.16.580700 — microbiology — Posted on 2024-02-17

2033 Engineering BCMA CAR T cells for myeloma-targeted cargo delivery

Kimman, T.; Cuenca, M.; Slomp, A.; Tieland, R. G.; Rockx-Brouwer, D.; Heijhuurs, S.; Meringa, A. D.; Boschloo, W.; Bosma, D. M.; Kroos, S.; lo Presti, V.; Nierkens, S.; Bovenschen, N.; Kuball, J.; Minnema, M. C.; Sebestyen, Z.; Peperzak, V.

10.1101/2024.02.14.580301 — immunology — Posted on 2024-02-17

2034 Novel 3-D macrophage spheroid model reveals reciprocal regulation of immunomechanical stress and mechano-immunological response

Burchett, A. A.; Siri, S.; Li, J.; Lu, X.; Datta, M.

10.1101/2024.02.14.580327 — immunology — Posted on 2024-02-17

2035 Degron-based bioPROTACs for controlling signaling in CAR T cells

Kim, M. S.; Bhargava, H. K.; Shavey, G. E.; Lim, W. A.; El-Samad, H.; Ng, A. H.

10.1101/2024.02.16.580396 — synthetic biology — Posted on 2024-02-17

2036 Transcriptional profiling during infection of potato NLRs and Phytophthora infestans effectors using cDNA enrichment sequencing

Kaur, A.; Singh, V.; Byrne, S. L.; Armstrong, M.; Adams, T. M.; Harrower, B.; Mullins, E.; Hein, I.

10.1101/2024.02.16.580628 — molecular biology — Posted on 2024-02-17

2037 Alternative translation initiation produces synaptic organizer proteoforms with distinct localization and functions

Lee, P. J.; Soares, A. R.; Sun, Y.; Fai, C.; Picciotto, M.; Guo, J. U.

10.1101/2024.02.16.580719 — molecular biology — Posted on 2024-02-17

2038 Loop extrusion-mediated plasmid DNA cleavage by the bacterial SMC Wadjet complex

Pradhan, B.; Deep, A.; Koenig, J.; Baaske, M.; Corbett, K.; Kim, E.

10.1101/2024.02.17.580791 — molecular biology — Posted on 2024-02-17

2039 Deciphering the History of ERK Activity from Fixed-Cell Immunofluorescence Measurements

Ram, A.; Pargett, M.; Choi, Y.; Murphy, D.; Cabel, M.; Kosaisawe, N.; Quon, G.; Albeck, J.

10.1101/2024.02.16.580760 — molecular biology — Posted on 2024-02-17

2040 Lytic transglycosylase repertoire diversity enables daughter cell separation and antibiotic resistance in Escherichia coli under acidic stress

Lee, C.-R.; Son, J. E.; Park, S. H.; Choi, U.

10.1101/2024.02.16.580723 — microbiology — Posted on 2024-02-17

2041 Glycolytic reprogramming shapes the epigenetic landscape of activated CD4+ T Cells in Juvenile Idiopathic Arthritis

Mocholi, E.; Chalkiadakis, T.; Gulersonmez, C.; Stigter, E.; Vastert, B.; van Loosdregt, J.; Prekovic, S.; Coffer, P.

10.1101/2024.02.14.580242 — immunology — Posted on 2024-02-17

2042 Characterization of gelling agents in callus inducing media: Physical properties and their effect on callus development

Sadot Muzika, N.; Kamai, T.; Williams, L. E.; Kleiman, M.

10.1101/2024.02.14.580317 — plant biology — Posted on 2024-02-17

2043 A Comprehensive Analysis of 3-UTRs in Caenorhabditis elegans

Murari, E.; Meadows, D.; Cuda, N.; Mangone, M.

10.1101/2024.02.15.580525 — genomics — Posted on 2024-02-17

2044 Human iPSC-derived Committed Cardiac Progenitors Generate Cardiac Tissue Grafts in a Swine Ischemic Cardiomyopathy Model without Triggering Ventricular Arrhythmias

Raval, A. N.; Schmuck, E. G.; Roy, S.; Saito, Y.; Zhou, T.; Conklin, J.; Hacker, T. A.; Koonce, C.; Boyer, M.; Stack, K.; Hebron, E.; Nagle, S. K.; Hsieh, P. C. H.; Kamp, T. J.

10.1101/2024.02.14.580375 — pathology — Posted on 2024-02-17

2045 Resistance to Naive and Formative Pluripotency Conversion in RSeT Human Embryonic Stem Cells

Chen, K. G.; Johnson, K. J.; Park, K.; Maric, D.; Yang, F.; Liu, W. F.; Fann, Y. C.; Mallon, B. S.; Robey, P. G.

10.1101/2024.02.16.580778 — cell biology — Posted on 2024-02-17

2046 Innervation of cranial muscles requires Mllt11/Af1q/Tcf7c function during trigeminal ganglion development

Zinck, N. W.; Stanton-Turcotte, D.; Witt, E. A.; Blommers, M.; Iulianella, A.

10.1101/2024.02.16.580667 — developmental biology — Posted on 2024-02-17

2047 Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

Mulligan, R. J.; Magaj, M. M.; Digilio, L.; Redemann, S.; Yap, C. C.; Winckler, B.

10.1101/2023.10.24.563658 — cell biology — Posted on 2024-02-17

2048 Nuclear pore complexes undergo Nup221 exchange during blood stage asexual replication of Plasmodium parasites.

Blauwkamp, J. A.; Ambekar, S. V.; Hussain, T.; Mair, G. R.; Beck, J. R.; Absalon, S.

10.1101/2024.02.16.580747 — cell biology — Posted on 2024-02-17

2049 Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity.

Katz, L. S.; Visser, E. J.; Plitzko, K. F.; Pennings, M.; Cossar, P. J.; Tse, I. L.; Kaiser, M.; Brunsveld, L.; Scott, D. K.; Ottmann, C.

10.1101/2024.02.16.580675 — cell biology — Posted on 2024-02-17

2050 Proteomic analysis uncovers clusterin-mediated disruption of actin-based contractile machinery in the trabecular meshwork to lower intraocular pressure

Soundararajan, A.; Wang, T.; Pattabiraman, P. P.

10.1101/2024.02.16.580757 — cell biology — Posted on 2024-02-17

2051 Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis

Martinez Garcia de la Torre, R. A.; Vallverdu, J.; Xu, Z.; Arino, S.; Aguilar-Bravo, B.; Ruiz Blazquez, P.; Fernandez Fernandez, M.; Navarro-Gascon, A.; Blasco-Roset, A.; Sanchez--Fernandez-de-Landa, P.; Pera Garcia, J.; Romero-Moya, D.; Ayuso Garcia, P.; Martinez Sanchez, C.; Zanatto, L.; Sererols, L.; Cantallops Vila, P.; Antoine, B.; Azkargorta, M.; Lozano, J. J.; Martinez-Chantar, M. L.; Giorgetti, A.; Elortza, F.; Planavila, A.; Varela, M.; Woodhoo, A.; Zorzano, A.; Graupera, I.; Moles, A.; Coll, M.; Affo, S.; Sancho-Bru, P.

10.1101/2024.02.15.577777 — cell biology — Posted on 2024-02-17

2052 A Reference Data Set for Circular Dichroism Spectroscopy Comprised of Validated Intrinsically Disordered Protein Models

Nagy, G.; Jones, N. C.; Hoffmann, S. V.; Grubmueller, H.

10.1101/2023.10.19.562942 — biophysics — Posted on 2024-02-17

2053 Diffusiophoresis promotes phase separation and transport of biomolecular condensates

Doan, V. S.; Alshareedah, I.; Singh, A.; Banerjee, P. R.; Shin, S.

10.1101/2023.07.03.547532 — biophysics — Posted on 2024-02-17

2054 SLAM/SAP signaling regulates discrete γδ T cell developmental checkpoints and shapes the innate-like γδ TCR repertoire

Mistri, S. K.; Hilton, B. M.; Horrigan, K. J.; Andretta, E. S.; Savard, R.; Dienz, O.; Hampel, K. J.; Gerrard, D. L.; Rose, J. T.; Sidiropoulos, N.; Majumdar, D.; Boyson, J. E.

10.1101/2024.01.10.575073 — immunology — Posted on 2024-02-17

2055 Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

Buhmann, Z.; Robinson, A. K.; Mattingley, J. B.; Rideaux, R.

10.1101/2024.02.15.580589 — neuroscience — Posted on 2024-02-17

2056 Microglia contribute to methamphetamine reinforcement and reflect persistent transcriptional and morphological adaptations to the drug

Vilca, S. J.; Margetts, A. V.; Fleites, I.; Wahlestedt, C.; Tuesta, L. M.

10.1101/2023.10.19.563168 — neuroscience — Posted on 2024-02-17

2057 The highly repetitive genome of Myxobolus sp., a myxozoan parasite of fathead minnows

Muthye, V. R.; Leon Coria, A.; Liu, H.; Finney, C. A. M.; Goater, C. P.; Wasmuth, J. D.

10.1101/2024.02.09.579586 — zoology — Posted on 2024-02-17

2058 Exploring unique sequence repeat patterns and secondary structures in rDNA internal transcribed spacers ITS1 and ITS2 for characterization of catfish species

IMRAN, M.; NAFEES, S.

10.1101/2024.01.10.575031 — zoology — Posted on 2024-02-17

2059 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

Revach, O.-Y.; Cicerchia, A. M.; Shorer, O.; Petrova, B.; Anderson, S.; Park, J.; Chen, L.; Mehta, A.; Wright, S. J.; McNamee, N.; Tal-Mason, A.; Cattaneo, G.; Tiwari, P.; Xie, H.; Sweere, J. M.; Cheng, L.-C.; Sigal, N.; Enrico, E.; Miljkovic, M.; Evans, S. A.; Nguyen, N.; Whidden, M. E.; Srinivasan, R.; Spitzer, M. H.; Sun, Y.; Sharova, T.; Lawless, A.; Michaud, W. A.; Rasmussen, M. Q.; Fang, J.; Palin, C.; Chen, F.; Wang, X.; Ferrone, C. R.; Lawrence, D. P.; Sullivan, R. J.; Liu, D.; Sachdeva, U. M.; Sen, D. R.; Flaherty, K. T.; Manguso, R. T.; Bod, L.; Kellis, M.; Boland, G. M.; Yizhak, K.;

10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-02-17

2060 {Omega}-Loop mutations control the dynamics of the active site by modulating a network of hydrogen bonds in PDC-3 β-lactamase

Chen, S.; Mack, A. R.; Hujer, A. M.; Bethel, C. R.; Bonomo, R. A.; Haider, S.

10.1101/2024.02.04.578824 — biophysics — Posted on 2024-02-17

2061 ANDES: a novel best-match approach for enhancing gene set analysis in embedding spaces

Li, L.; Dannenfelser, R.; Cruz, C.; Yao, V.

10.1101/2023.11.21.568145 — bioinformatics — Posted on 2024-02-17

2062 Partial RNA Design

Runge, F.; Franke, J. K. H.; Fertmann, D.; Backofen, R.; Hutter, F.

10.1101/2023.12.29.573656 — bioinformatics — Posted on 2024-02-17

2063 Multi-ancestry polygenic risk scores using phylogenetic regularization

Layne, E.; Zabad, S.; Li, Y.; Blanchette, M.

10.1101/2024.02.14.580313 — bioinformatics — Posted on 2024-02-17

2064 GLiDe: a web-based genome-scale CRISPRi sgRNA design tool for prokaryotes

Xiang, T.; Feng, H.; Xing, X.-H.; Zhang, C.

10.1101/2022.11.25.517898 — bioinformatics — Posted on 2024-02-17

2065 Haplotype-aware sequence alignment to pangenome graphs

Chandra, G.; Gibney, D.; Jain, C.

10.1101/2023.11.15.566493 — bioinformatics — Posted on 2024-02-17

2066 A Quantum Computing Pipeline for Real World Drug Discovery: From Algorithm to Quantum Hardware

Li, W.; Yin, Z.; Li, X.; Ma, D.; Yi, S.; Zhang, Z.; Zou, C.; Bu, K.; Dai, M.; Yue, J.; Chen, Y.; Zhang, X.; Zhang, S.

10.1101/2024.01.08.574600 — bioinformatics — Posted on 2024-02-17

2067 Supercontinuum intrinsic fluorescence imaging heralds free view of living systems

Wang, G.; Li, L.; Liao, X.; Wang, S.; Mitchell, J.; Rabel, C.; Luo, S.; Shi, J.; Sorrells, J. E.; Iyer, R. R.; Aksamitiene, E.; Renteria, C. A.; Chaney, E. J.; Milner, D. J.; Wheeler, M. B.; Gillette, M. U.; Schwing, A.; Chen, J.; Tu, H.

10.1101/2024.01.26.577383 — bioengineering — Posted on 2024-02-17

2068 Firefighter Helmets and Cervical Intervertebral Kinematics: An OpenSim-Based Biomechanical Study

Paulon, G.; Subramanian, S.; Chowdhury, S.

10.1101/2023.11.16.567468 — bioengineering — Posted on 2024-02-17

2069 Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates

Meng, Z.; Saei, A. A.; Zhang, X.; Lyu, H.; Gharibi, H.; Lundstrom, S. L.; Vegvari, A.; Gaetani, M.; Zubarev, R. A.

10.1101/2024.02.14.579877 — biochemistry — Posted on 2024-02-17

2070 Structural and biochemical characterization of the mitomycin C repair exonuclease MrfB

Manthei, K. A.; Munson, L. M.; Nandakumar, J.; Simmons, L. A.

10.1101/2024.02.15.580553 — biochemistry — Posted on 2024-02-17

2071 Locomotion-dependent auditory gating to the parietal cortex mediates flexible multisensory decisions

Choi, I.; Lee, S.-H.

10.1101/2024.02.14.580296 — animal behavior and cognition — Posted on 2024-02-17

2072 Striatal Dopamine Can Enhance Learning, Both Fast and Slow, and Also Make it Cheaper

Westbrook, A.; van den Bosch, R.; Hofmans, L.; Papadopetraki, D.; Maatta, J. I.; Collins, A. G. E.; Frank, M. J.; Cools, R.

10.1101/2024.02.14.580392 — animal behavior and cognition — Posted on 2024-02-17

2073 Sex-specific fear acquisition following early life stress is linked to amygdala glutamate metabolism

Bordes, J.; Bajaj, T.; Miranda, L.; van Doeselaar, L.; Brix, L. M.; Narayan, S.; Yang, H.; Mitra, S.; Kovarova, V.; Springer, M.; Kleigrewe, K.; Mueller-Myhsok, B.; Gassen, N. C.; Schmidt, M. V.

10.1101/2024.02.15.580479 — animal behavior and cognition — Posted on 2024-02-17

2074 Predicting cell type-specific epigenomic profiles accounting for distal genetic effects

Murphy, A. E.; Beardall, W.; Rei, M.; Phuycharoen, M.; Skene, N. G.

10.1101/2024.02.15.580484 — genomics — Posted on 2024-02-17

2075 Linear Interaction Between Replication and Transcription Shapes DNA Break Dynamics at Recurrent DNA Break Clusters

Corazzi, L.; Ionasz, V.; Andrejev, S.; Wang, L.-C.; Vouzas, A.; Giaisi, M.; Di Muzio, G.; Ding, B.; Marx, A.; Henkenjohann, J.; Allers, M. M.; Gilbert, D. M.; Wei, P.-C.

10.1101/2023.08.22.554340 — genomics — Posted on 2024-02-17

2076 Evaluation and optimization of sequence-based gene regulatory deep learning models

Rafi, A. M.; Nogina, D.; Penzar, D.; Lee, D.; Lee, D.; Kim, N.; Kim, S.; Kim, D.; Shin, Y.; Kwak, I.-Y.; Meshcheryakov, G.; Lando, A.; Zinkevich, A.; Kim, B.-C.; Lee, J.; Kang, T.; Vaishnav, E. D.; Yadollahpour, P.; DREAM Challenge Consortium, R. P.; Kim, S.; Albrecht, J.; Regev, A.; Gong, W.; Kulakovskiy, I. V.; Meyer, P.; de Boer, C.

10.1101/2023.04.26.538471 — genomics — Posted on 2024-02-17

2077 Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an SCN5A negative charge: structural insights into the gating pore hypothesis

Roden, D. M.; Glazer, A. M.; Yang, T.; Page, D.; Fouda, M.; Wada, Y.; Lancaster, M. C.; O'Neill, M. J.; Muhammad, A.; Gao, X.; Ackerman, M. J.; Sanatani, S.; Ruben, P.; Li, B.

10.1101/2024.02.13.580021 — genetics — Posted on 2024-02-17

2078 50,000 years of Evolutionary History of India: Insights from ~2,700 Whole Genome Sequences

Kerdoncuff, E.; Skov, L.; Patterson, N.; Zhao, W.; Lueng, Y. Y.; Schellenberg, G. D.; Smith, J. A.; Dey, S.; Ganna, A.; Dey, A.; Kardia, S. L. R.; Lee, J.; Moorjani, P.

10.1101/2024.02.15.580575 — evolutionary biology — Posted on 2024-02-17

2079 The evolution of environmentally mediated social interactions and posthumous spite under isolation by distance

Mullon, C.; Pena, J.; Lehmann, L.

10.1101/2023.09.22.558951 — evolutionary biology — Posted on 2024-02-17

2080 Ivermectin resistance in dung beetles exposed for multiple generations

Tokman, D. G.; Torres, A. A.; Baena-Diaz, F.; Bustos, C.; Martinez M, I.

10.1101/2023.05.08.539900 — ecology — Posted on 2024-02-17

2081 SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis

Magdaleno, C.; Tschumperlin, D.; Rajasekaran, N.; Varadaraj, A.

10.1101/2024.02.14.580347 — cell biology — Posted on 2024-02-17

2082 A CPF-like phosphatase module links transcription termination to chromatin silencing

Mateo Bonmati, E.; Montez, M.; Maple, R.; Fiedler, M.; Fang, X.; Saalbach, G.; Passmore, L. A.; Dean, C. A.

10.1101/2023.07.06.547976 — molecular biology — Posted on 2024-02-17

2083 Proximal termination generates a transcriptional state that determines the rate of establishment of Polycomb silencing

Menon, G.; Mateo Bonmati, E.; Reeck, S.; Maple, R.; Wu, Z.; Ietswaart, R.; Dean, C.; Howard, M.

10.1101/2023.07.06.547969 — molecular biology — Posted on 2024-02-17

2084 DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes

Lorzadeh, A.; Ye, G.; Sharma, S.; Jadhav, U.

10.1101/2024.02.11.579850 — molecular biology — Posted on 2024-02-17

2085 Infant and Adult Human Intestinal Enteroids are Morphologically and Functionally Distinct

Adeniyi-Ipadeola, G. O.; Hankins, J. D.; Kambal, A.; Zeng, X.-L.; Patil, K.; Poplaski, V.; Bomidi, C.; Nguyen-Phuc, H.; Grimm, S. L.; Coarfa, C.; Stossi, F.; Crawford, S. E.; Blutt, S. E.; Speer, A. L.; Estes, M. K.; Ramani, S.

10.1101/2023.05.19.541350 — microbiology — Posted on 2024-02-17

2086 Activation of intestinal immunity by pathogen effector-triggered aggregation of lysosomal TIR-1/SARM1

Tse-Kang, S.; Wani, K. A.; Peterson, N. D.; Page, A.; Pukkila-Worley, R.

10.1101/2023.12.04.569946 — immunology — Posted on 2024-02-17

2087 Multi-omic profiling of pathogen-stimulated primary immune cells

Salz, R.; Vorsteveld, E. E.; van der Made, C. I.; Kersten, S.; Stemerdink, M.; Hsieh, T.; Mhlanga, M.; Netea, M.; Volders, P.-J.; Hoischen, A.; 't Hoen, P. A. C.

10.1101/2023.09.13.557514 — immunology — Posted on 2024-02-17

2088 Anterior thalamus functional connectivity with cortical regions underpinning prospective memory: a 7-Tesla fMRI seed-based study

Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.

10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-02-17

2089 μSim: A goal-driven framework for elucidating the neural control of movement through musculoskeletal modeling

Almani, M. N.; Lazzari, J.; Chacon, A.; Saxena, S.

10.1101/2024.02.02.578628 — neuroscience — Posted on 2024-02-17

2090 Meta-Analysis Reveals That Explore-Exploit Decisions are Dissociable by Activation in the Dorsal Lateral Prefrontal Cortex and the Anterior Cingulate Cortex

Sazhin, D.; Dachs, A.; Smith, D. V.

10.1101/2023.10.21.563317 — neuroscience — Posted on 2024-02-17

2091 Investigating altered limbic reward system in Huntington's Disease: Implications for apathy

Bikou, V.; de Vicente, I.; De Paepe, A. E.; Garcia-Gorro, C.; Rodriguez-Dechicha, N.; Vaquer, I.; Calopa, M.; de Diego-Balaguer, R.; Camara, E.

10.1101/2024.02.13.580195 — neuroscience — Posted on 2024-02-17

2092 Opiate anticipation,opiate induced anatomical changes in hypocretin (Hcrt, orexin) neurons and opiate induced microglial activation are blocked by the dual Hcrt receptor antagonist suvorexant, while opiate analgesia is maintained

McGregor, R.; Wu, M.-F.; Thannickal, T.; Siegel, J.

10.1101/2023.09.22.559044 — neuroscience — Posted on 2024-02-17

2093 Kappa opioid receptor induces epigenetic silencing of brain derived neurotropic factor via HDAC5 in treatment-resistant depression

YADAV, A.; DOGRA, S.; KUMAR, B. A.; KUMARI, P.; KUMAR, A.; DASH, M. K.; Yadav, P. N.

10.1101/2023.09.18.558045 — neuroscience — Posted on 2024-02-17

2094 Scaling Properties for Artificial Neural Network Models of a Small Nervous System

Simeon, Q.; Venancio, L. R.; SKUHERSKY, M.; Yang, G.; Boyden, E. S.; Nayebi, A.

10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-02-17

2095 YY1 mutations disrupt corticogenesis through a cell-type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs

Pereira, M. F.; Finazzi, V.; Rizzuti, L.; Aprile, D.; Aiello, V.; Mollica, L.; Riva, M.; Soriani, C.; Dossena, F.; Shyti, R.; Castaldi, D.; Tenderini, E.; Carminho-Rodrigues, M. T.; Bally, J. F.; de Vries, B. B. A.; Gabriele, M.; Vitriolo, A.; Testa, G.

10.1101/2024.02.16.580337 — neuroscience — Posted on 2024-02-17

2096 Spatial periodicity in grid cell firing is explained by a neural sequence code of 2-D trajectories

R.G., R.; Ascoli, G. A.; Sutton, N. M.; Dannenberg, H.

10.1101/2023.05.30.542747 — neuroscience — Posted on 2024-02-17

2097 Neuron-specific RNA-sequencing reveals different mechanisms in peripheral neurons after nerve injury

Bolivar, S.; Sanz, E.; Ovelleiro, D.; Zochodne, D. W.; Udina, E.

10.1101/2023.07.21.549881 — neuroscience — Posted on 2024-02-17

2098 Cortical beta oscillations map to shared brain networks modulated by dopamine

Chikermane, M.; Weedmeester, L.; Rajamani, N.; Köhler, R. M.; Merk, T.; Vanhoecke, J.; Horn, A.; Neumann, W.-J.

10.1101/2024.02.16.580657 — neuroscience — Posted on 2024-02-17

2099 Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts

Rottet, S.; Rourke, L. M.; Pabuayon, I. C. M.; Phua, S. Y.; Yee, S.; Weerasooriya, H. N.; Wang, X.; Mehra, H. S.; Nguyen, N. D.; Long, B. M.; Moroney, J. V.; Price, G. D.

10.1101/2024.02.14.580295 — plant biology — Posted on 2024-02-17

2100 Functional Characterisation of the ATOH1 Molecular Subtype Indicates a Pro-Metastatic Role in Small Cell Lung Cancer

Catozzi, A.; Peiris-Pages, M.; Humphrey, S.; Revill, M.; Morgan, D.; Roebuck, J.; Chen, Y.; Davies-Williams, B.; Lallo, A.; Galvin, M.; Pearce, S. P.; Kerr, A.; Priest, L.; Foy, V.; Carter, M.; Caeser, R.; Chan, J.; Rudin, C. M.; Blackhall, F.; Frese, K. K.; Dive, C.; Simpson, K. L.

10.1101/2024.02.16.580247 — cancer biology — Posted on 2024-02-17

2101 Ultrastructure expansion microscopy (U-ExM) of mouse and human kidneys for analysis of subcellular structures

Langner, E.; Puapatanakul, P.; Pudlowski, R.; Alsabbagh, D. Y.; Miner, J.; Horani, A.; Dutcher, S. K.; Brody, S. L.; Wang, J.; Suleiman, H. Y.; Mahjoub, M. R.

10.1101/2024.02.16.580708 — cell biology — Posted on 2024-02-17

2102 Atox1-Cyclin D1 Loop Activity is Critical for Survival of Tumors with Inactivated TP53

Kuchur, O. A.; Pogodaeva, S. S.; Scherbakova, A. V.; Tsymbal, S. A.

10.1101/2024.02.14.580254 — cancer biology — Posted on 2024-02-16

2103 Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum: A containment strategy for toxic intermediates?

Ziegler, S. J.; Knott, B.; Gruber, J. N.; Hengge, N. N.; Xu, Q.; Olson, D. G.; Romero, E. E.; Joubert, L.-M.; Bomble, Y. J.

10.1101/2024.02.16.580662 — biophysics — Posted on 2024-02-16

2104 PIMENTA: PIpeline for MEtabarcoding through Nanopore Technology used for Authentication

van der Vorst, V.; Thijssen, M.; Fronen, B. J.; de Groot, A.; Maathuis, M. A. M.; Nijhuis, E.; Polling, M.; Stassen, J.; Voorhuijzen-Harink, M. M.; Jak, R.

10.1101/2024.02.14.580249 — bioinformatics — Posted on 2024-02-16

2105 Tissue Tension and Strain as Indicators of Suction-mediated Cutaneous DNA Transfection: A Parametric Study

Jhumur, N. C.; Lallow, E. O.; Nachtigal, C.; Yeo, D.; Kwon, I.; Park, Y. K.; Roberts, C. C.; Zahn, J. D.; Shreiber, D. I.; Shan, J. W.; Singer, J. P.; Maslow, J. N.; Lin, H.

10.1101/2024.02.15.580412 — bioengineering — Posted on 2024-02-16

2106 The membrane insertion of the pro-apoptotic protein Bax is a Tom22-dependent multi-step process: a study in nanodiscs

Rouchidane Eyitayo, A.; Daury, L.; Priault, M.; Manon, S.

10.1101/2024.02.16.580668 — biochemistry — Posted on 2024-02-16

2107 Molecular and computational studies of ADGRG6 reveal its extracellular CUB domain as a key regulator of cAMP signaling

Dintzner, E.; Bandekar, S. J.; Leon, K.; Arac, D.

10.1101/2024.02.16.580607 — biochemistry — Posted on 2024-02-16

2108 Community stability increases the predictability of microeukaryote community coalescence outcomes

Vass, M.; Szekely, A.; Carlsson-Graner, U.; Wikner, J.; Andersson, A.

10.1101/2024.02.14.580275 — ecology — Posted on 2024-02-16

2109 Enterobacterial repetitive intergenic consensus (ERIC)-PCR analysis as a trace for Burkholderia pseudomallei in Myanmar

Chantratita, N.; Su, K. K.; Tribuddharat, C.; Aung, N. M.

10.1101/2024.02.15.580599 — microbiology — Posted on 2024-02-16

2110 Sub-optimal activity of gut microbiome functional pathways increases the odds of Irritable Bowel Syndrome in a large adult human population

Patridge, E.; Gorakshakar, A.; Molusky, M. M.; Ogundijo, O.; Julian, C.; Hu, L.; Vuyisich, M.; Wohlman, R.; Banavar, G.

10.1101/2024.02.15.580548 — microbiology — Posted on 2024-02-16

2111 High density genomic surveillance and risk profiling of clinical Listeria monocytogenes subtypes in Germany, 2018-2021

Halbedel, S.; Wamp, S.; Lachmann, R.; Holzer, A.; Pietzka, A.; Ruppitsch, W.; Wilking, H.; Flieger, A.

10.1101/2024.02.16.580625 — microbiology — Posted on 2024-02-16

2112 Initial Characterization of Canine T-cell Receptor Repertoires Using RNA-seq Data from Different Diseases and Tissues

Zhang, M.; Ho, K.-L.; Zhao, S.

10.1101/2024.02.14.580390 — immunology — Posted on 2024-02-16

2113 Global sensitivity analysis for investigation of bacterial physiology in complex media with FBA-PRCC

Sorokin, A.; Goryanin, I.

10.1101/2024.02.14.580207 — systems biology — Posted on 2024-02-16

2114 Diverse transcriptome reprogramming trajectories underlie quantitative disease resistance at the species level

Delplace, F.; Khafif, M.; Raffaele, S.

10.1101/2024.02.15.580486 — plant biology — Posted on 2024-02-16

2115 Engineering the cyanobacterial ATP-driven BCT1 bicarbonate transporter for functional targeting to C3 plant chloroplasts

Rottet, S.; Rourke, L. M.; Pabuayon, I. C. M.; Phua, S. Y.; Yee, S.; Weerasooriya, H. N.; Wang, X.; Mehra, H. S.; Nguyen, N. D.; Long, B. M.; Moroney, J. V.; Price, G. D.

10.1101/2024.02.14.580295 — plant biology — Posted on 2024-02-16

2116 DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION

Zhang, M.; Liu, M.; Ren, Z.; Wang, W.; Upadhyay, K.; Asico, L. A.; Armando, I.; Jia, Y.; Wang, P.; Xue, Y.; Wang, X.

10.1101/2024.02.14.580405 — physiology — Posted on 2024-02-16

2117 VICTree - a Variational Inference method for Clonal Tree reconstruction

Melin, H.; Zampinetti, V.; McPherson, A.; Lagergren, J.

10.1101/2024.02.14.580312 — cancer biology — Posted on 2024-02-16

2118 Novel approach for carbon-wise utilization of lignin-related compounds by synergistically employing anaerobic and aerobic bacteria

Merilainen, E.; Efimova, E.; Santala, V.; Santala, S.

10.1101/2024.02.14.580265 — bioengineering — Posted on 2024-02-16

2119 Systemically targeting monocytic MDSCs using dendrimers and their cell-level biodistribution kinetics

Littrell, C. A.; Takacs, G. P.; Siva Sankara, C.; Sherman, A.; Rubach, K. A.; Garcia, J. S.; Bell, C.; Harrison, J. K.; Zhang, F.

10.1101/2024.02.14.580395 — bioengineering — Posted on 2024-02-16

2120 Bottlebrush polyethylene glycol nanocarriers translocate across human airway epithelium via molecular architecture enhanced endocytosis

He, Z.-J.; Huang, B.; Cai, L.

10.1101/2024.02.15.580508 — bioengineering — Posted on 2024-02-16

2121 The metabolome of individuals with knee osteoarthritis is influenced by 18-months of an exercise and weight loss intervention and sex: the IDEA trial

Welhaven, H.; Welfley, A.; Bothner, B.; Messier, S.; Loeser, R.; June, R.

10.1101/2024.02.15.580523 — biochemistry — Posted on 2024-02-16

2122 The activation chain of the broad-spectrum antiviral bemnifosbuvir at atomic resolution

Chazot, A.; Zimberger, C.; Feracci, M.; Moussa, A.; Good, S.; Sommadossi, J.-P.; ALVAREZ, K.; Ferron, F.; Canard, B.

10.1101/2024.02.16.580631 — biochemistry — Posted on 2024-02-16

2123 Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Kobren, S. N.; Moldovan, M. A.; Reimers, R.; Traviglia, D.; Li, X.; Barnum, D.; Veit, A.; Willett, J.; Berselli, M.; Ronchetti, W.; Sherwood, R.; Krier, J.; Kohane, I. S.; Undiagnosed Diseases Network, ; Sunyaev, S. R.

10.1101/2024.02.13.580158 — genetics — Posted on 2024-02-16

2124 A critical reexamination of recovered SARS-CoV-2 sequencing data

Debarre, F.; Hensel, Z.

10.1101/2024.02.15.580500 — evolutionary biology — Posted on 2024-02-16

2125 Transinfection of Wolbachia wAlbB into Culex quinquefasciatus mosquitoes does not alter vector competence for Hawaiian avian malaria (Plasmodium relictum GRW4)

Kilpatrick, A. M.; Seidl, C. M.; Ipsaro, I. J.; Garrison, C. E.; Fabbri, G.; Howell, P. I.; McGowan, A. G.; White, B. J.; Mitchell, S. N.

10.1101/2024.02.16.580617 — ecology — Posted on 2024-02-16

2126 H-NS is a bacterial transposon capture protein

Cooper, C.; Legood, S.; Wheat, R. L.; Forrest, D.; Sharma, P.; Haycocks, J. R.; Grainger, D. C.

10.1101/2024.02.16.580519 — microbiology — Posted on 2024-02-16

2127 Molecular switching of a DNA-sliding clamp to a repressor mediates long-range gene silencing

McLean, T. C.; Balaguer-Perez, F.; Chandanani, J.; Thomas, C. M.; Aicart-Ramos, C.; Burick, S.; Olinares, P. D. B.; Gobbato, G.; Mundy, J. E. A.; Chait, B. T.; Lawson, D. M.; Darst, S. A.; Campbell, E. A.; Moreno-Herrero, F.; Le, T. B. K.

10.1101/2024.02.16.579611 — microbiology — Posted on 2024-02-16

2128 Microbial community assembly during aging of food waste-derived hydrochar: key bacterial guilds mediate nutrient dynamics

Ruan, Y.; Wang, Z.; Tan, S.; Xu, H.; Wang, L.; Ren, L.; Liu, Z.; Guo, S.; Shen, Q.; Xu, G.; Ling, N.

10.1101/2024.02.16.580608 — microbiology — Posted on 2024-02-16

2129 The polysaccharide capsule of Acinetobacter baumannii affects bacterial adhesion and natural transformation

Whiteway, C.; de Pillecyn, V.; Maure, A.; Breine, A.; Valcek, A.; Van Buylaere, J.; Van der Henst, C.

10.1101/2024.02.15.580542 — microbiology — Posted on 2024-02-16

2130 In bacterial membranes lipid II changes the stability of pores formed by the antimicrobial peptide nisin

Sheridan, M. S.; Hansmann, U. H. E.; Pandey, P.

10.1101/2024.02.14.580365 — biophysics — Posted on 2024-02-16

2131 Revealing nanoscale structure and interfaces of protein and polymer condensates via cryo-electron microscopy

RIZVI, A.; Favetta, B.; Jaber, N.; Lee, Y.-k.; Jiang, J.; Idris, N.; Schuster, B. S.; Dai, W.; Patterson, J. P.

10.1101/2024.02.15.577400 — biophysics — Posted on 2024-02-16

2132 Circadian rhythms of macrophages are altered by the acidic pH of the tumor microenvironment

Knudsen-Clark, A. M.; Mwangi, D.; Cazarin, J.; Hablitz, L. M.; Kim, M.; Altman, B. J.

10.1101/2024.02.14.580339 — immunology — Posted on 2024-02-16

2133 Exploitation of CD3ζ to enhance TCR expression levels and antigen-specific T cell function

Degirmencay, A.; Thomas, S.; Holler, A.; Stauss, H.

10.1101/2024.02.14.580308 — immunology — Posted on 2024-02-16

2134 The Body Knows Better: Sensorimotor signals reveal "Suboptimal" inference of the Sense of Agency in the human mind

Applebaum, A.; Netzer, O.; Stern, Y.; Zvilichovsky, Y.; Mashiah, O.; Salomon, R.

10.1101/2024.02.14.579431 — neuroscience — Posted on 2024-02-16

2135 Resistify - A rapid and accurate annotation tool to identify NLRs and study their genomic organisation

Smith, M.; Jones, J. T.; Hein, I.

10.1101/2024.02.14.580321 — plant biology — Posted on 2024-02-16

2136 Meiotic recombination in Leptosphaeria maculans favours the rise of transgressive isolates adapted to a nonhost species, Brassica carinata

Noah, J. M.; Gorse, M.; Romain, C.-A.; Gay, E. J.; Rouxel, T.; Balesdent, M.-H.; Soyer, J. L.

10.1101/2024.02.15.580423 — pathology — Posted on 2024-02-16

2137 Phasing Diploid Genome Assembly Graphs with Single-Cell Strand Sequencing

Henglin, M.; Ghareghani, M.; Harvey, W.; Porubsky, D.; Koren, S.; Eichler, E. E.; Ebert, P.; Marschall, T.

10.1101/2024.02.15.580432 — bioinformatics — Posted on 2024-02-16

2138 Population genomics of the rice landrace Acuce reveals exceptional dynamics of immune receptors

De Mita, S.; Duan, S.; Li, X.; Pelissier, R.; Mathieu, L.; Li, J.; Ma, L.; Li, Z.; Liao, J.; He, X.; Zhu, Y.; Li, C.; Dong, Y.; Morel, J.-b.; Huang, H.

10.1101/2024.02.15.579491 — genomics — Posted on 2024-02-16

2139 A flow cytometry protocol for accurate and precise measurement of plant genome size using frozen material

Soni, A.; Constantin, L.; Furtado, A.; Henry, R.

10.1101/2024.02.14.580322 — genomics — Posted on 2024-02-16

2140 Genome-AC-GAN: Enhancing Synthetic Genotype Generationthrough Auxiliary Classification

Ahronoviz, S.; Gronau, I.

10.1101/2024.02.14.580420 — genomics — Posted on 2024-02-16

2141 Epigenomic profiling of active regulatory elements by enrichment of unmodified CpG dinucleotides

Tosti, L.; Mould, C.; Gatehouse, I.; Camargo, A.; Smith, A.; Ubych, K.; Laird, P. W.; Kennefick, J.; Neely, R. K.

10.1101/2024.02.16.575381 — genomics — Posted on 2024-02-16

2142 Sex differences in immune function and disease risk are not easily explained by an evolutionary mismatch

Arner, A. M.; Muhoya, B.; Rozado, M. S.; Gurven, M. R.; Kahumbu, J.; Kamau, J.; Kinyua, P.; Lotukoi, F.; Martins, D. J.; Miano, C.; Montague, M. J.; Njeru, S.; Peng, J.; Straub, P.; Watowich, M. M.; Davis, L. K.; Snyder-Mackler, N.; Ayroles, J. F.; Lea, A. J.

10.1101/2024.02.13.580011 — evolutionary biology — Posted on 2024-02-16

2143 Phylogenomic and genomic analysis reveals unique and shared genetic signatures of Mycobacterium kansasii complex species

Machado, E.; Vasconcellos, S.; Gomes, L.; Catanho, M.; Ramos, J.; de Carvalho, L.; Goldenberg, T.; Dalcolmo, M.; Redner, P.; Caldas, P.; Campos, C.; Lourenco, M. C.; Lasunskaia, E.; Mussi, V.; Spinasse, L.; Vinhas, S.; Rigouts, L.; Cogneau, S.; de Rijk, P.; Utpatel, C.; Kaustova, J.; van der Laan, T.; de Neeling, H.; Rastogi, N.; Levina, K.; Kutt, M.; Mokrousov, I.; Zhuravlev, V.; Makhado, N.; Zolnir-Dovc, M.; Jankovic, V.; de Waard, J.; Sisco, M.; van Soolingen, D.; Niemann, S.; de Jong, B. C.; Meehan, C. J.; Suffys, P.

10.1101/2024.02.14.579889 — evolutionary biology — Posted on 2024-02-16

2144 Experimental evolution for improved post-infection survival selects for increased disease resistance in Drosophila melanogaster

Basu, A.; Tekade, K.; Singh, A.; Das, P. N.; Prasad, N. G.

10.1101/2024.02.14.580293 — evolutionary biology — Posted on 2024-02-16

2145 Fusion, fission, and scrambling of the bilaterian genome in Bryozoa

Lewin, T. D.; Liao, I. J.-Y.; Chen, M.-E.; Bishop, J. D. D.; Holland, P. W. H.; Luo, Y.-J.

10.1101/2024.02.15.580425 — evolutionary biology — Posted on 2024-02-16

2146 Robust Neutralization of SARS-CoV-2 Variants Including JN.1 and BA.2.87.1 by Trivalent XBB Vaccine-Induced Antibodies

Wang, X.; Jiang, S.; Ma, W.; Li, C.; Liu, C.; Xie, F.; Zhu, J.; Zhan, Y.; Jiang, S.; Li, M.; Zhang, Y.; Wang, P.

10.1101/2024.02.16.580615 — microbiology — Posted on 2024-02-16

2147 Exposure to cooler temperatures during pupal development increases Aedes aegypti vector competence and the R0 for Zika virus

Pohlenz, T. D.; Vela, J.; Reyna, M.; Fredregill, C.; Hur, B.; Erraguntla, M.; Lawley, M.; Debboun, M.; Adelman, Z. N.; Ndeffo-Mbah, M. L.; Myles, K. M.

10.1101/2024.02.16.580619 — microbiology — Posted on 2024-02-16

2148 Targeting a specific motor control process reveals an age-related compensation that adapts movement to gravity environment

MATHIEU, R.; Chambellant, F.; Thomas, E.; Papaxanthis, C.; Hilt, P.; Manckoundia, P.; Mourey, F.; Gaveau, J.

10.1101/2024.02.16.576683 — neuroscience — Posted on 2024-02-16

2149 YY1 mutations disrupt corticogenesis and cytoarchitecture through a cell-type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs

10.1101/2024.02.16.580337 — neuroscience — Posted on 2024-02-16

2150 Effects of sodium butyrate and rosemary leaves on performance, biochemical parameters, immune status, and carcass traits of broiler chickens

Shalaby, M. A.; Saifan, H. Y.; Abo-El-Sooud, K.; Tony, M. A.; Yassin, A. M.

10.1101/2024.02.14.580269 — zoology — Posted on 2024-02-16

2151 R-Loop Functions in Brca1-Associated Mammary Tumorigenesis

Chiang, H.-C.; Qi, L.; Mitra, P.; Hu, Y.; Li, R.

10.1101/2024.02.14.580374 — cancer biology — Posted on 2024-02-16

2152 Licensing and competition of stem cells at the niche combine to regulate tissue maintenance

Garcia-Tejera, R.; Amoyel, M.; Grima, R.; Schumacher, L.

10.1101/2024.02.15.580493 — developmental biology — Posted on 2024-02-16

2153 Deep Learning Based Models for Preimplantation Mouse and Human Development

Proks, M.; Salehin, N.; Brickman, J. M.

10.1101/2024.02.16.580649 — developmental biology — Posted on 2024-02-16

2154 Functional correlation between WRN and SAMHD1 in end-resection

Perdichizzi, B.; Pichierri, P.

10.1101/2024.02.15.580497 — cell biology — Posted on 2024-02-16

2155 Immuno-Scanning Electron Microscopy of Islet Primary Cilia

Sviben, S.; Polino, A. J.; Melena, I.; Hughes, J. W.

10.1101/2024.02.16.580695 — cell biology — Posted on 2024-02-16

2156 Adaptation of human cell populations to different levels of centriole amplification involves a two-step response

Dias Louro, M. A.; Peneda, C.; Bank, C.; Bettencourt Dias, M.

10.1101/2024.02.15.580424 — cell biology — Posted on 2024-02-16

2157 Near-optimal information relay by the neuronal population of layer 4 barrel cortex

Revah, O.; Wolf, F.; Gutnick, M. J.; Neef, A.

10.1101/2024.02.15.580451 — neuroscience — Posted on 2024-02-16

2158 Deciphering the function of intrinsic and genomics-driven epigenetic heterogeneity in head and neck cancer progression with single-nucleus CUT&RUN

Womerley, H.; Muliaditan, D.; DasGupta, R.; Cheow, L. F.

10.1101/2024.02.14.580230 — cancer biology — Posted on 2024-02-16

2159 Biophysics of microRNA-34a targeting and its influence on down-regulation

Sweetapple, L.; Kosek, D.; Banijamali, E.; Becker, W.; Mueller, J.; Karadiakos, C.; Baronti, L.; Guzzetti, I.; Schritt, D.; Chen, A.; Andersson, E. R.; Petzold, K.

10.1101/2024.02.14.580117 — biophysics — Posted on 2024-02-16

2160 A Major Role of Class III HD-ZIPs in Promoting Sugar Beet Cyst Nematode Syncytium Formation in Arabidopsis

Liu, X.; Mitchum, M. G.

10.1101/2024.02.15.580549 — plant biology — Posted on 2024-02-16

2161 Neuroestrogens facilitate male-typical behaviors by potentiating androgen receptor signaling in medaka

Nishiike, Y.; Maki, S.; Miyazoe, D.; Nakasone, K.; Kamei, Y.; Todo, T.; Ishikawa-Fujiwara, T.; Ohno, K.; Usami, T.; Nagahama, Y.; Okubo, K.

10.1101/2024.02.13.580203 — physiology — Posted on 2024-02-16

2162 Analog epigenetic cell memory by graded DNA methylation

Palacios, S.; Bruno, S.; Weiss, R.; Salibi, E.; Kane, A.; Ilia, K.; Del Vecchio, D.

10.1101/2024.02.13.580200 — bioengineering — Posted on 2024-02-16

2163 UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation

Tiedemann, R.; Hrit, J.; Du, Q.; Wiseman, A. K.; Eden, H. E.; Dickson, B. M.; Kong, X.; Chomiak, A.; Vaughan, R. M.; Hebert, J. M.; David, Y.; Zhou, W. M.; Baylin, S.; Jones, P. A.; Clark, S.; Rothbart, S. B.

10.1101/2024.02.13.580169 — genomics — Posted on 2024-02-16

2164 Distinct sets of molecular characteristics define tumor-rejecting neoantigens

Adams, A. C.; Macy, A. M.; Borden, E. S.; Herrmann, L. M.; Brambley, C. A.; Ma, T.; Li, X.; Hughes, A.; Roe, D. J.; Mangold, A. R.; Buetow, K. H.; Wilson, M. A.; Baker, B. M.; Hastings, K. T.

10.1101/2024.02.13.579546 — immunology — Posted on 2024-02-16

2165 Age-associated B cell infiltration in salivary glands represents a hallmark of Sjögren's-like disease in aging mice

Bagavant, H.; Durslewicz, J.; Pyclik, M.; Makuch, M.; Papinska, J. A.; Deshmukh, U. S.

10.1101/2024.02.13.580185 — immunology — Posted on 2024-02-16

2166 The flow of reward information through neuronal ensembles in the accumbens

Arroyo, B.; Hernandez-Lemus, E.; Gutierrez, R.

10.1101/2024.02.15.580379 — neuroscience — Posted on 2024-02-16

2167 Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells

Fleiner, A. S.; Kolnier, D.; Hagger-Vaughan, N.; Raeder, J.; Storm, J. F.

10.1101/2024.02.14.579884 — neuroscience — Posted on 2024-02-16

2168 Adeno-Associated Viral Tools to Trace Neural Development and Connectivity Across Amphibians

Jaeger, E. C. B.; Vijatovic, D.; Deryckere, A.; Zorin, N.; Nguyen, A. L.; Ivanian, G.; Woych, J.; Arnold, R. C.; Ortega Gurrola, A.; Shvartsman, A.; Barbieri, F.; Toma, F. A.; Gorbsky, G. J.; Horb, M. E.; Cline, H. T.; Shay, T. F.; Kelley, D. B.; Yamaguchi, A.; Shein-Idelson, M.; Tosches, M. A.; Sweeney, L. B.

10.1101/2024.02.15.580289 — neuroscience — Posted on 2024-02-16

2169 Vitamin D is Glucoprotective in Aging Males but Not Females

Ginnard, O. Z. B.; Morales, M.; Youn, J. Y.; Xu, Y.; Sisley, S. R.

10.1101/2024.02.13.580162 — physiology — Posted on 2024-02-16

2170 Multifocal Ectopic Purkinje Premature Contractions due to neutralization of an SCN5A negative charge: structural insights into the gating pore hypothesis

Roden, D. M.; Glazer, A. M.; Yang, T.; Page, D.; Fouda, M.; Wada, Y.; Lancaster, M. C.; O'Neill, M. J.; Muhammad, A.; Gao, X.; Ackerman, M. J.; Sanatani, S.; Ruben, P.; Li, B.

10.1101/2024.02.13.580021 — genetics — Posted on 2024-02-16

2171 A Spatial Prioritization of Conifer Management to Defend and Grow Sagebrush Cores

Reinhardt, J. R.; Maestas, J.; Naugle, D. E.; Bedrosian, G.; Doherty, K.; Kumar, A.

10.1101/2024.02.13.579706 — ecology — Posted on 2024-02-16

2172 TLR9 activation in large wound induces tissue repair and hair follicle regeneration via gamma delta T cells

Li, X.; Yang, Y.; Yi, Z.; Xu, Z.; Chen, S.; An, T.; Zhou, F.; Deng, C.; Man, Y.; Hu, C.

10.1101/2024.02.15.580480 — cell biology — Posted on 2024-02-16

2173 Multifunctional biomimetic porphyrin-lipid nanoparticles - novel nanoscale theranostics for atherosclerotic cardiovascular disease

Nankivell, V.; Sandeman, L.; Stretton, L. G.; Vidanapathirana, A.; Rajora, M. A.; Chen, J.; Tieu, W.; Psaltis, P. J.; Tan, J. T. M.; Chen, Y.-C.; Peter, K.; Zheng, G.; Bursill, C. A.

10.1101/2024.02.13.580218 — cell biology — Posted on 2024-02-16

2174 The Bacillus subtilis yqgC-sodA operon protects magnesium-dependent enzymes by supporting manganese efflux

Sachla, A. J.; Soni, V.; Pineros, M.; Luo, Y.; Im, J. J.; Rhee, K. Y.; Helmann, J. D.

10.1101/2024.02.14.580342 — microbiology — Posted on 2024-02-16

2175 Milteforan, a promising veterinary commercial product against feline sporotrichosis

Carnero, L. G.; dos Reis, T. F.; Diehl, C.; de Castro, P. A.; Pontes, L.; Pinzan, C. F.; Goldman, G. H.

10.1101/2024.02.14.580352 — microbiology — Posted on 2024-02-16

2176 Genotype-specific expression of uncle fester suggests a role in allorecognition education in a basal chordate

Taketa, D. A.; Cengher, L.; Rodriguez, D.; Langenbacher, A. D.; De Tomaso, A. W.

10.1101/2024.02.13.580188 — immunology — Posted on 2024-02-16

2177 Spatiotemporal Changes in Netrin/Dscam1 Signaling Dictate Axonal Projection Direction in Drosophila Small Ventral Lateral Clock Neurons

Liu, J.; Wang, Y.; Han, J.; Tian, Y.

10.1101/2024.02.15.580478 — neuroscience — Posted on 2024-02-16

2178 Importin-β specific nuclear transport defects recapitulate phenotypic and transcriptional alterations seen in neurodegeneration

Plessis-Belair, J.; Ravano, K.; Han, E.; Janniello, A.; Molina, C.; Sher, R.

10.1101/2024.02.14.580338 — neuroscience — Posted on 2024-02-16

2179 UNC-16 interacts with LRK-1 and WDFY-3 to regulate the termination of axon growth.

Drozd, C. J.; Chowdhury, T. A.; Quinn, C. C.

10.1101/2024.02.15.580526 — neuroscience — Posted on 2024-02-16

2180 Cancer-Specific Alterations in Nuclear Matrix Proteins Determined by Multi-omics Analyses of Ductal Carcinoma in Situ

Almutairy, A.; Alhamed, A.; Grant, S.; Sarachine Falso, M. J.; Day, B.; Simmons, C. R.; Latimer, J. J.

10.1101/2024.02.13.580215 — cancer biology — Posted on 2024-02-16

2181 Identification of retinal tau oligomers, citrullinated tau, and other tau isoforms in early and advanced AD and relations to disease status

Shi, H.; Mirzaei, N.; Koronyo, Y.; Davis, M. R.; Robinson, E.; Braun, G. M.; Jallow, O.; Rentsendorj, A.; Ramanujan, V. K.; Fert-Bober, J.; Kramerov, A. A.; Ljubimov, A. V.; Schneider, L. S.; Tourtellotte, W. G.; Hawes, D.; Schneider, J. A.; Black, K. L.; Kayed, R.; Selenica, M.-L. B.; Lee, D. C.; Fuchs, D.-T.; Koronyo-Hamaoui, M.

10.1101/2024.02.13.579999 — pathology — Posted on 2024-02-16

2182 Structural enrichment attenuates colitis-associated colon cancer

Sykes, D. J.; Solanki, S.; Chukkapalli, S.; Williams, K.; Newman, E. A.; Resnicow, K.; Shah, Y. M. J.

10.1101/2024.02.13.580099 — cancer biology — Posted on 2024-02-16

2183 The Interaction of NF-κB Transcription Factor with Centromeric Chromatin

Filliaux, S. B.; Bertelsen, C.; Baughman, H. E. R.; Komives, E. A. A.; Lyubchenko, Y. L.

10.1101/2024.02.13.580208 — biophysics — Posted on 2024-02-16

2184 INTREPPPID - An Orthologue-Informed Quintuplet Network for Cross-Species Prediction of Protein-Protein Interaction

Szymborski, J.; Emad, A.

10.1101/2024.02.13.580150 — bioinformatics — Posted on 2024-02-16

2185 Diversity in the Utilization of Different Molecular Classes of Dissolved Organic Matter by Heterotrophic Marine Bacteria

Givati, S. H.; Forchielli, E. J.; Aharonovich, D.; Barak, N.; Weissberg, O.; Belkin, N.; Rahav, E.; Segre, D.; Sher, D.

10.1101/2024.02.13.580157 — microbiology — Posted on 2024-02-16

2186 Neutrophils in People Living With HIV-1 on antiretroviral treatment conserve their cytokine and chemokine secretion capacity and display enhanced expression of Fc receptors

Marsile-Medun, S.; Souchard, M.; Abba Moussa, D.; Lorin, V.; Mouquet, H.; Reynaud, E.; Dibsy, R.; TUAILLON, E.; MURIAUX, D.; Pugniere, M.; Ngo, G.; Naranjo-Gomez, M.; Pelegrin, M.

10.1101/2024.02.13.580065 — immunology — Posted on 2024-02-16

2187 Predicting the macrovascular contribution to resting-state fMRI functional connectivity at 3 Tesla: A model-informed approach

Zhong, X.; Polimeni, J. R.; Chen, J. J.

10.1101/2024.02.13.580143 — biophysics — Posted on 2024-02-16

2188 Soft Tissue Mechanics in Hip Distraction after Total Knee Arthroplasty: A Finite Element Analysis

Soehnlen, S. M.; Sadeqi, S.; Kumaran, Y.; Tripathi, S.; Jones, R. K.; Sohn, D. H.; Goel, V. K.

10.1101/2024.02.13.580129 — bioengineering — Posted on 2024-02-16

2189 A SENSORIZED 3D-PRINTED KNEE TEST RIG FOR EXPERIMENTAL VALIDATION OF PATELLAR TRACKING AND CONTACT SIMULATION AFTER TOTAL KNEE REPLACEMENT

MICHAUD, F.; Mouzo, F.; Dopico, D.; Cuadrado, J.

10.1101/2024.02.13.580095 — bioengineering — Posted on 2024-02-16

2190 MobileLAMP: A portable, low-cost, open-source device for isothermal nucleic acid amplification

Bhupathi, M.; Hegde, S.; Devarapu, G. C. R.; Molloy, J. C.

10.1101/2024.02.13.580127 — bioengineering — Posted on 2024-02-16

2191 SAFE-OPT: A Bayesian optimization algorithm for learning optimal deep brain stimulation parameters with safety constraints

Cole, E. R.; Connolly, M.; Ghetiya, M.; Sendi, M.; Kashlan, A.; Eggers, T.; Gross, R. E.

10.1101/2024.02.13.580142 — bioengineering — Posted on 2024-02-16

2192 SIMHYB 2: a software tool to explore and illustrate evolutionary forces in Population Genetics teaching and research. Application to Conservation Genetics

Soto, A.; Rodriguez-Martinez, D.; Lopez de Heredia, U.

10.1101/2024.02.13.580073 — scientific communication and education — Posted on 2024-02-16

2193 CoRAL accurately resolves extrachromosomal DNA genomestructures with long-read sequencing

Zhu, K.; Jones, M. G.; Luebeck, J.; Bu, X.; Yi, H.; Hung, K. L.; Wong, I. T.-L.; Zhang, S.; Mischel, P. S.; Chang, H. Y.; Bafna, V.

10.1101/2024.02.15.580594 — cancer biology — Posted on 2024-02-16

2194 Matrix-rigidity cooperates with biochemical cues in M2 macrophage activation through increased nuclear deformation and chromatin accessibility

Shin, S.-J.; Bayarkhangai, B.; Tsogtbaataar, K.; Yuxuan, M.; Kim, S.-H.; Kim, Y.-J.; Kim, D.; Kim, D.-H.; Lee, J.-H.; Hyun, J.; Kim, H.-W.

10.1101/2024.02.13.579995 — bioengineering — Posted on 2024-02-16

2195 E93 controls adult differentiation by repressing broad in Drosophila

Cruz, J.; Urena, E.; Franch-Marro, X.; Martin, D.

10.1101/2024.02.14.580315 — developmental biology — Posted on 2024-02-16

2196 Diverse Fgfr1 signaling pathways and endocytic trafficking regulate early mesoderm development

Clark, J. F.; Soriano, P.

10.1101/2024.02.16.580629 — developmental biology — Posted on 2024-02-16

2197 DNA methylation machinery is involved in development and reproduction in the viviparous pea aphid (Acyrthosiphon pisum).

Yoon, K. J.; Williams, S.; Duncan, E.

10.1101/2024.02.14.579807 — developmental biology — Posted on 2024-02-16

2198 Arf GTPase-Activating proteins ADAP1 and ARAP1 regulate incorporation of CD63 in multivesicular bodies

Suzuki, K.; Okawa, Y.; Akter, S.; Ito, H.; Shiba, Y.

10.1101/2024.02.15.580439 — cell biology — Posted on 2024-02-16

2199 A Vascular Dissection and Rupture Linked Metabolite Acts Via BLT2 Receptor

Wang, Y.; Li, Y.; Yu, J.; Chen, W.; Tan, X.; Xu, X.; Lin, R.; Wang, X.; Jiang, W.; Du, J.

10.1101/2024.02.15.580482 — cell biology — Posted on 2024-02-16

2200 Prosaposin is cleaved into saposins by multiple cathepsins in a progranulin-regulated fashion

Hodul, M.; Lane-Donovan, C.; Mambou, E. A.; Yang, Z.; Kao, A. W.

10.1101/2024.02.15.580326 — cell biology — Posted on 2024-02-16

2201 Lysosomal uptake of mtDNA mitigates heteroplasmy

Kakanj, P.; Bonse, M.; Gokmen, A.; Gaedke, F.; Molla, B.; Vogelsang, E.; Schauss, A.; Wodarz, A.; Pla-Martin, D.

10.1101/2024.02.16.580263 — cell biology — Posted on 2024-02-16

2202 The co-chaperone DNAJA2 buffers proteasomal degradation of cytosolic proteins with missense mutations

Baker, H. A.; Bernardini, J. P.; Csizmok, V.; Madero, A.; Kamat, S.; Eng, H.; Lacoste, J.; Yeung, F.; Comyn, S.; Calabrese, G.; Taipale, M.; Raught, B.; Mayor, T.

10.1101/2024.02.15.580437 — cell biology — Posted on 2024-02-16

2203 The p300 KAT inhibitor, A-485, inhibits melanogenesis and melanin content in human melanocytes

Grbic, N.; Waddell, A. R.; Leibowitz, K.; Wyant, W. A.; Collard, M.; Alani, R. M.

10.1101/2024.02.14.580089 — cell biology — Posted on 2024-02-16

2204 The Role of Sex in the Effects of Smoking and Nicotine in Cardiovascular Function, Atherosclerosis, and Inflammation

Salazar, G.; Centner, A. M.; Cullen, A. E.; Khalili, L.; Ukhanov, V.; Hill, S.; Deitado, R.; Hwang, H. S.; Azeez, T.; La Favor, J. D.; Laitano, O.; Parvatiyar, M. S.

10.1101/2024.02.13.580217 — cell biology — Posted on 2024-02-16

2205 The 15-min (Sub)Cellular Proteome

Shen, B.; Pade, L. R.; Nemes, P.

10.1101/2024.02.15.580399 — cell biology — Posted on 2024-02-16

2206 CRM1 regulates androgen receptor stability and impacts DNA repair pathways in prostate cancer, independent of the androgen receptor.

Kumar, R.; Mendonca, J.; Shetty, A.; Yang, Y.; Owoyemi, O.; Wilson, L. C.; Boyapati, K.; Topiwala, D.; Thomas, N.; Nguyen, H.; Luo, J.; Paller, C. J.; Denmeade, S. R.; Carducci, M. A.; Kachhap, S. K.

10.1101/2024.02.13.579966 — cancer biology — Posted on 2024-02-16

2207 Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy

Radmacher, N.; Nevskyi, O.; Gallea, J. I.; Thiele, J. C.; Gregor, I.; Rizzoli, S. O.; Enderlein, J.

10.1101/2023.08.23.554438 — biophysics — Posted on 2024-02-16

2208 METASPACE-ML: Metabolite annotation for imaging mass spectrometry using machine learning

Wadie, B.; Stuart, L.; Rath, C. M.; Drotleff, B.; Mamedov, S.; Alexandrov, T.

10.1101/2023.05.29.542736 — bioinformatics — Posted on 2024-02-16

2209 How do plant RNA viruses overcome the negative effect of Muller s ratchet despite strong transmission bottlenecks?

LAFFORGUE, G.; LEFEBVRE, M.; MICHON, T.; Elena, S. F.

10.1101/2023.08.01.550272 — evolutionary biology — Posted on 2024-02-16

2210 Cost-benefit analysis of cryogenic electron tomography subtomogram averaging of chaperonin MmCpn at near atomic resolution.

Zhao, Y.; Schmid, M. F.; Chiu, W.

10.1101/2024.01.30.577584 — biophysics — Posted on 2024-02-16

2211 Effects of local and landscape factors on paddy field arthropod diversity: from species to communities

Ou, J.-A.; Huang, C.-L.; Tsai, C.-W.; Ho, C.-K.

10.1101/2024.01.17.575529 — ecology — Posted on 2024-02-16

2212 Odor source distance is predictable from time-histories of odor statistics for large scale outdoor plumes

Nag, A.; van Breugel, F.

10.1101/2023.07.20.549973 — ecology — Posted on 2024-02-16

2213 A comparison of the parasitoid wasp species richness of tropical forest sites in Peru and Uganda - subfamily Rhyssinae (Hymenoptera: Ichneumonidae)

Hopkins, T.; Tuomisto, H.; Gomez, I. C.; Sääksjärvi, I. E.

10.1101/2023.08.23.554460 — zoology — Posted on 2024-02-16

2214 Model-based dimensionality reduction for single-cell RNA-seq using generalized bilinear models

Nicol, P. B.; Miller, J. W.

10.1101/2023.04.21.537881 — bioinformatics — Posted on 2024-02-16

2215 Overcoming the nutritional immunity by engineering iron scavenging bacteria for cancer therapy

Huang, S.-W.; Lim, S.-K.; Yu, Y.-A.; Pan, Y.-C.; Lien, W.-J.; Mou, C.-Y.; Hu, C.-M. J.; Mou, K. Y.

10.1101/2023.07.25.550605 — bioengineering — Posted on 2024-02-16

2216 Human in vivo midtarsal and subtalar joint kinematics during walking, running, and hopping

Behling, A.-V.; Welte, L.; Kelly, L.; Rainbow, M.

10.1101/2023.09.15.558017 — bioengineering — Posted on 2024-02-16

2217 Integrated Plankton and Trace Metal Analysis asIndicators of Organic Pollution Threats fromCarp-Cultured Ponds to Adjacent Ecosystems:Implications for Sustainability

Mukherjee, M.; Jarzembowski, P.; Polechonski, R.; Prockow, J.

10.1101/2024.01.26.577523 — ecology — Posted on 2024-02-16

2218 A cautionary tale on organelle proteome prediction algorithms: limits and opportunities

Gould, S. B.; Magiera, J.; Garcia Garcia, C.; Raval, P. K.

10.1101/2023.12.18.572050 — cell biology — Posted on 2024-02-16

2219 A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions

Farrell, R. J.; Bredvik, K. G.; Hoppa, M. B.; Hennegan, S. T.; Brown, T. A.; Ryan, T. A.

10.1101/2024.02.15.580492 — cell biology — Posted on 2024-02-16

2220 Oxytocin signaling regulates maternally-directed behavior during early life

Zelmanoff, D.; Kaufman, M.; Dine, J.; Wietek, J.; Litvin, A.; Abraham, S.; Cohen, S.; Yizhar, O.

10.1101/2024.02.15.580483 — neuroscience — Posted on 2024-02-15

2221 Hidden hearing loss in hereditary demyelinating neuropathies: insights from Charcot-Marie-Tooth mouse models

Cassinotti, L. R.; Ji, L.; Yuk, M. C.; Desai, A. S.; Cass, N. D.; Amir, Z. A.; Corfas, G.

10.1101/2023.12.14.571732 — neuroscience — Posted on 2024-02-16

2222 Multi-species community platform for comparative neuroscience in teleost fish

Vohra, S.; Herrera, K.; Tavhelidse-Suck, T.; Wittbrodt, J.; Knoblich, S.; Seleit, A.; Aulehla, A.; Boulanger-Weill, J.; Chambule, S.; Aspiras, A.; Santoriello, C.; Fishman, M. C.; Hege, H.-C.; Baum, D.; Engert, F.; Isoe, Y.

10.1101/2024.02.14.580400 — neuroscience — Posted on 2024-02-16

2223 Spatially Resolved Transcriptomic Signatures of Hippocampal Subregions and Arc-Expressing Ensembles in Active Place Avoidance Memory

Vingan, I. P.; Phatarpekar, S.; Tung, V. S. K.; Hernandez, A. I.; Evgrafov, O. V.; Alarcon, J. M.

10.1101/2023.12.30.573225 — neuroscience — Posted on 2024-02-16

2224 The lateral habenula is required for maternal behavior in the mouse dam

Benedict, J.; Cudmore, R. H.; Oden, D.; Spruell, A.; Linden, D. J.

10.1101/2024.02.12.577842 — neuroscience — Posted on 2024-02-16

2225 Ultra-wide angle neuroimaging: insights into immersive scene representation

Park, J.; Soucy, E.; Segawa, J.; Mair, R.; Konkle, T.

10.1101/2023.05.14.540275 — neuroscience — Posted on 2024-02-16

2226 Rubisco supplies pyruvate for the 2-C-methyl-D-erythritol-4-phosphate pathway

Evans, S. E.; Xu, Y.; Bergman, M. E.; Ford, S.; Liu, Y.; Sharkey, T.; Phillips, M. A.

10.1101/2024.01.28.577108 — plant biology — Posted on 2024-02-16

2227 Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure

Ishigohoka, J.; Bascon-Cardozo, K.; Bours, A.; Fuss, J.; Rhie, A.; Mountcastle, J.; Haase, B.; Chow, W.; Collins, J.; Howe, K.; Uliano-Silva, M.; Fedrigo, O.; Jarvis, E. D.; Perez-Tris, J.; Illera, J. C.; Liedvogel, M.

10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2024-02-16

2228 Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

Vanhooydonck, M.; Verlee, M.; Silva, M. S.; Pottie, L.; Boel, A.; Van Impe, M.; De Saffel, H.; Caboor, L.; Tapaneeyaphan, P.; Bonnin, A.; Segers, P.; De Clercq, A.; Willaert, A.; Syx, D.; Sips, P.; Callewaert, B.

10.1101/2024.02.12.580022 — developmental biology — Posted on 2024-02-16

2229 Transient Impairment in Microglial Function Causes Sex-Specific Deficits in Synaptic and Hippocampal Function in Mice Exposed to Early Adversity

Ahmed, S.; Polis, B.; Jamwal, S.; Sanganahalli, B. G.; MacDowell Kaswan, Z.; Islam, R.; Kim, D.; Bowers, C.; Giuliano, L.; Biederer, T.; Hyder, F.; Kaffman, A.

10.1101/2024.02.14.580284 — neuroscience — Posted on 2024-02-15

2230 Shared and unique consequences of Joubert Syndrome gene dysfunction on the zebrafish central nervous system

Noble, A. R.; Masek, M.; Hofmann, C.; Cuoco, A.; Rusterholz, T. D. S.; Ozkoc, H.; Greter, N. R.; Vladimirov, N.; Kollmorgen, S.; Stoeckli, E.; Bachmann-Gagescu, R.

10.1101/2024.02.15.580456 — neuroscience — Posted on 2024-02-15

2231 Aberrant axon initial segment is an indicator for task-independent neural activity in autism model mice

Otani, Y.; Koga, K.; Kawabata, R.; Liu, X.; Miyajima, H.; Takumi, T.; Fujitani, M.

10.1101/2024.02.15.580571 — neuroscience — Posted on 2024-02-15

2232 Long-term adaptation of prefrontal circuits in a mouse model of NMDAR hypofunction

Ponserre, M. A.; Ionescu, T. M.; Franz, A. A.; Deiana, S.; Schuelert, N.; Lamla, T.; Williams, R. H.; Wotjak, C. T.; Hobson, S.; Dine, J. P. P.; Omrani, A.

10.1101/2024.02.15.580421 — neuroscience — Posted on 2024-02-15

2233 Single Transcript Level Atlas of Oxytocin and the Oxytocin Receptor in the Mouse Brain

Ryu, V.; Gumerova, A. A.; Pevnev, G.; Korkmaz, F.; Kannangara, H.; Cullen, L.; Witztum, R.; Sims, S. L.; Frolinger, T.; Moldavski, O.; Barak, O.; Cao, J. J.; Lizneva, D.; Goosens, K. A.; Yuen, T.; Zaidi, M.

10.1101/2024.02.15.580498 — physiology — Posted on 2024-02-15

2234 CellsFromSpace: A fast, accurate and reference-free tool to deconvolve and annotate spatially distributed Omics data

Thuilliez, C.; Moquin-Beaudry, G.; Khneisser, p.; Marques Da Costa, M. E.; Karkar, S.; Boudhouche, H.; Drubay, D.; Audinot, B.; Geoerger, B.; Scoazec, J.-Y.; Gaspar, N.; Marchais, A.

10.1101/2023.08.30.555558 — bioinformatics — Posted on 2024-02-15

2235 Innate face detectors in the nidopallium of young domestic chicks

Kobylkov, D.; Rosa-Salva, O.; Zanon, M.; Vallortigara, G.

10.1101/2024.02.15.580445 — animal behavior and cognition — Posted on 2024-02-15

2236 Pleotropic effects of a recessive COL1A2 mutation occurring in a mouse model of severe osteogenesis imperfecta

Corcelli, M.; Sagar, R.; Petzendorfer, E.; Hasan, M. M.; de Vries, H. I.; van Dijk, F. S.; David, A. L.; Guillot, P. V.

10.1101/2024.02.15.580510 — genetics — Posted on 2024-02-15

2237 Brain-handedness associations depend on how and when handedness is measured

Tejavibulya, L.; Horien, C.; Fredricks, C.; Ficek-Tani, B.; Westwater, M. L.; Scheinost, D.

10.1101/2024.02.15.580563 — neuroscience — Posted on 2024-02-15

2238 Ion-channel degeneracy and heterogeneities in the emergence of signature physiological characteristics of dentate gyrus granule cells

Kumari, S.; Narayanan, R.

10.1101/2024.02.15.580453 — neuroscience — Posted on 2024-02-15

2239 Dynamics of dominance: maneuvers, contests, and assessment in the posture-scalemovements of interacting zebrafish

O'Shaughnessy, L.; Izawa, T.; Masai, I.; Shaevitz, J.; Stephens, G.

10.1101/2023.11.21.567896 — biophysics — Posted on 2024-02-15

2240 A Fast Interferometric Beam Shaper for Multi-Emitter 3D MINFLUX

Geismann, M. K.; Gomez-Segalas, A.; Passera, A.; Shirzadian, M.; Balzarotti, F.

10.1101/2023.12.09.570565 — biophysics — Posted on 2024-02-15

2241 Benchmarking of Hi-C tools for scaffolding de novo genome assemblies

Obinu, L.; Trivedi, U.; Porceddu, A.

10.1101/2023.05.16.540917 — genomics — Posted on 2024-02-15

2242 Cis-regulatory variation in relation to sex and sexual dimorphism in Drosophila melanogaster

Mishra, P.; Barrera, T. S.; Grieshop, K. H.; Agrawal, A. F.

10.1101/2022.09.20.508724 — evolutionary biology — Posted on 2024-02-15

2243 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps

Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.

10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2024-02-15

2244 Tree diversity increases forest temperature buffering

Schnabel, F.; Beugnon, R.; Yang, B.; Richter, R.; Eisenhauer, N.; Huang, Y.; Liu, X.; Wirth, C.; Cesarz, S.; Fichtner, A.; Perles-Garcia, M. D.; Hähn, G. J. A.; Härdtle, W.; Kunz, M.; Castro Izaguirre, N. C.; Niklaus, P. A.; von Oheimb, G.; Schmid, B.; Trogisch, S.; Wendisch, M.; Ma, K.; Bruelheide, H.

10.1101/2023.09.11.556807 — ecology — Posted on 2024-02-15

2245 PCP Auto Count: A Novel Fiji/ImageJ plug-in for automated quantification of planar cell polarity and cell counting

Stansak, K. L.; Baum, L. D.; Ghosh, S.; Thapa, P.; Vanga, V.; Walters, B. J.

10.1101/2024.01.30.578047 — developmental biology — Posted on 2024-02-15

2246 Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2

Ehlers, L.; Hombrouck, A.; Wouters, M.; Pillay, B.; Delafontaine, S.; Bucciol, G.; Baggio, M.; Dzhus, M.; Ebstein, F.; Jacquemyn, M.; De Somer, L.; Schrijvers, R.; Vanderschueren, S.; Cassiman, D.; Kirchner, M.; Mertins, P.; Kallinich, T.; Daelemans, D.; Agostinis, P.; Moens, L.; Meyts, I.

10.1101/2023.10.25.564037 — immunology — Posted on 2024-02-15

2247 Counter-regulation of RNA stability by UPF1 and TDP43

Gomez, N.; Hsieh, C.; Li, X.; Dykstra, M.; Waksmacki, J.; Altheim, C.; Bechar, Y.; Klim, J.; Zaepful, B.; Rothstein, J.; Tank, E. M.; Barmada, S. J.

10.1101/2024.01.31.578310 — neuroscience — Posted on 2024-02-15

2248 Simulations predict preferred Mg2+ coordination in a nonenzymatic primer extension reaction center

Mittal, S.; Nisler, C.; Szostak, J. W.

10.1101/2023.02.03.527041 — biophysics — Posted on 2024-02-15

2249 SpyMask Enables Combinatorial Assembly of Bispecific Binders

Driscoll, C. L.; Keeble, A. H.; Howarth, M.

10.1101/2023.08.31.555700 — bioengineering — Posted on 2024-02-15

2250 PI-(3,5)P2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9

Kokane, S.; Meier, P.; Gulati, A.; Matsuoka, R.; Pipatpolkai, T.; Albano, G.; Delemotte, L.; Fuster, D.; Drew, D.

10.1101/2023.09.10.557050 — biochemistry — Posted on 2024-02-15

2251 Too hot or too disturbed? Temperatures more than hikers affect circadian activity of females in northern chamois

Thel, L.; Garel, M.; Marchand, P.; Bourgoin, G.; Loison, A.

10.1101/2023.02.03.527075 — animal behavior and cognition — Posted on 2024-02-15

2252 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.

10.1101/2023.04.02.535219 — genomics — Posted on 2024-02-15

2253 Genome-wide association reveals novel insights into the molecular mechanisms regulating stem volume in Pinus taeda

Aono, A. H.; Bajay, S. K.; Francisco, F. R.; de Souza, A. P.

10.1101/2022.12.06.519371 — genetics — Posted on 2024-02-15

2254 A molecular atlas of plastid and mitochondrial evolution from algae to angiosperms

Raval, P. K.; MacLeod, A. I.; Gould, S. B.

10.1101/2023.09.01.555919 — evolutionary biology — Posted on 2024-02-15

2255 Old, broad-leaved stands support both high biodiversity and carbon storage in German forests

Springer, K.; Manning, P.; Boesing, A. L.; Ammer, C.; Fiore-Donno, A. M.; Fischer, M.; Goldmann, K.; Le Provost, G.; Overmann, J.; Ruess, L.; Schoening, I.; Seibold, S.; Sikorski, J.; Neyret, M.

10.1101/2024.02.06.578731 — ecology — Posted on 2024-02-15

2256 Calcyphosine is a microtubule-associated protein required for spindle formation and function

Setu, B.; Nie, Q.; Echele, G.; Spencer, S. A.

10.1101/2023.12.29.573632 — cell biology — Posted on 2024-02-15

2257 Discovery of an endogenous DNA virus in the amphibian killing fungus and its association with pathogen genotype and virulence

Clemons, R.; Yacoub, M.; Faust, E.; Toledo, L. F.; Jenkinson, T. S.; Carvalho, T.; Simmons, D. R.; Kalinka, E.; Fritz-Laylin, L. K.; James, T. Y.; Stajich, J. E.

10.1101/2023.03.16.532857 — microbiology — Posted on 2024-02-15

2258 Sample pooling inflates error rates in between-sample comparisons: an empirical investigation of the statistical properties of count-based data

Taylor, M.; Vega, N.

10.1101/2022.07.25.501406 — microbiology — Posted on 2024-02-15

2259 Assembly of neuron- and radial glial cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

Mubuchi, A.; Takechi, M.; Nishio, S.; Matsuda, T.; Itoh, Y.; Sato, C.; Kitajima, K.; Kitagawa, H.; Miyata, S.

10.1101/2022.09.03.506497 — neuroscience — Posted on 2024-02-15

2260 Learning to segment self-generated from externally caused optic flow through sensorimotor mismatch circuits

Brucklacher, M.; Pezzulo, G.; Mannella, F.; Galati, G.; Pennartz, C.

10.1101/2023.11.15.567170 — neuroscience — Posted on 2024-02-15

2261 Neuron-specific RNA-sequencing reveals different mechanisms in peripheral neurons after nerve injury

Bolivar, S.; Sanz, E.; Ovelleiro, D.; Zochodne, D. W.; Udina, E.

10.1101/2023.07.21.549881 — neuroscience — Posted on 2024-02-15

2262 Dendrites support formation and reactivation of sequential memories through Hebbian plasticity

Quaresima, A.; Fitz, H.; Duarte, R.; Hagoort, P.; Petersson, K. M.

10.1101/2023.09.26.559322 — neuroscience — Posted on 2024-02-15

2263 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens

Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.

10.1101/2023.05.17.541117 — physiology — Posted on 2024-02-15

2264 Quantitative model and physical mechanisms of iRBC membrane curling during egress of malaria parasites

Nick, G.; Parmeggiani, A.; KAJAVA, A. V.

10.1101/2024.02.13.579773 — biophysics — Posted on 2024-02-15

2265 Proteus: exploring protein structure generation for enhanced designability and efficiency

Wang, C.; Qu, Y.; Peng, Z.; Wang, Y.; Zhu, H.; Chen, D.; Cao, L.

10.1101/2024.02.10.579791 — bioinformatics — Posted on 2024-02-15

2266 Protein domain embeddings for fast and accurate similarity search

Iovino, B. G.; Tang, H.; Ye, Y.

10.1101/2023.11.27.567555 — bioinformatics — Posted on 2024-02-15

2267 Comparing sparse inertial sensor setups for sagittal-plane walking and running reconstructions

Dorschky, E.; Nitschke, M.; Mayer, M.; Weygers, I.; Gassner, H.; Seel, T.; Eskofier, B.; Koelewijn, A.

10.1101/2023.05.25.542228 — bioengineering — Posted on 2024-02-15

2268 ShapeProt: Top-down Protein Design with 3D Protein Shape Generative Model

Lee, Y.; Kim, J.

10.1101/2023.12.03.567710 — biochemistry — Posted on 2024-02-15

2269 The online metacognitive control of decisions

Benon, J.; Lee, D. G.; Hopper, W.; Verdeil, M.; Pessiglione, M.; Vinckier, F.; Bouret, S.; Rouault, M.; Lebouc, R.; Pezzulo, G.; Schreiweis, C.; Burguiere, E.; Daunizeau, J.

10.1101/2023.01.02.522463 — animal behavior and cognition — Posted on 2024-02-15

2270 Pangenomic landscapes shape the genetic circuit performance in a Stutzerimonas biodesign toolkit

Chan, D. T. C.; Bernstein, H. C.

10.1101/2024.02.15.580380 — synthetic biology — Posted on 2024-02-15

2271 Bending Unwinds DNA

Chandrasekhar, S.; Swope, T. P.; Fadaei, F.; Hollis, D. R.; Bricker, R.; Houser, D.; Portman, J.; Schmidt, T. L.

10.1101/2024.02.14.579968 — biophysics — Posted on 2024-02-15

2272 Axolotl mandible regeneration occurs through mechanical gap closure and a shared regenerative program with the limb

Kramer, J.; Aires, R.; Keeley, S. D.; Schröder, T. A.; Lauer, G.; Sandoval-Guzman, T.

10.1101/2024.02.14.580108 — developmental biology — Posted on 2024-02-15

2273 Unlocking prophage potential: In silico and experimental analysis of a novel Mycobacterium fortuitum LysinB containing a peptidoglycan-binding domain

Das, R.; Nadar, K.; Arora, R.; Bajpai, U.

10.1101/2024.02.15.580446 — molecular biology — Posted on 2024-02-15

2274 Investigating T cell Recruitment in Atherosclerosis using a novel Human 3D Tissue-Culture Model reveals the role of CXCL12 in intraplaque neovessels

Parma, L.; Sachs, N.; Li, Z.; Merchant, K.; Sobczak, N.; Slutter, B.; Maegdefessel, L.; Weber, C.; Megens, R.; Duchene, J.

10.1101/2024.02.14.580316 — molecular biology — Posted on 2024-02-15

2275 Lipid A double bond position determination using ozone and laser-induced dissociation

Mikhael, A.; Petrosova, H.; Smith, D.; Ernst, R. K.; Goodlett, D. R.

10.1101/2024.02.15.580351 — microbiology — Posted on 2024-02-15

2276 Metagenome-assembled genomes provide insight into the microbial taxonomy and ecology of the Buhera Soda Pans, Zimbabwe

Mangoma, N.; Zhou, N.; Ncube, T.

10.1101/2024.02.15.580475 — microbiology — Posted on 2024-02-15

2277 A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells

Mondal, P.; Alyateem, G.; Mitchell, A. V.; Gottesman, M. M.

10.1101/2024.02.15.580539 — cancer biology — Posted on 2024-02-15

2278 Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer

Yang, X.; Ma, X.; Croucher, D. R.; Nguyen, E. V.; Clark, K. C.; Hu, C.; Latham, S. L.; Zhao, T.; Bayly-Jones, C.; Nguyen, V. C. B.; Shin, S.; Nguyen, L. K.; Cotton, T. R.; Chueh, A. C.; Sian, T. C. L. K.; Stratton, M. M.; Ellisdon, A. M.; Daly, R. J.

10.1101/2024.02.14.580406 — cancer biology — Posted on 2024-02-15

2279 ChemGLaM: Chemical-Genomics Language Models for Compound-Protein Interaction Prediction

Koyama, T.; Tsumura, H.; Matsumoto, S.; Okita, R.; Kojima, R.; Okuno, Y.

10.1101/2024.02.13.580100 — bioinformatics — Posted on 2024-02-15

2280 The human Shu complex promotes RAD51 activity by modulating RPA dynamics on ssDNA.

Hengel, S. R.; Oppenheimer, K.; Smith, C.; Schaich, M.; Rein, H. L.; Martino, J.; Darrah, K.; Ezekwenna, O. C.; Burton, K. R.; Van Houten, B.; Spies, M.; Bernstein, K. A.

10.1101/2024.02.14.580393 — biochemistry — Posted on 2024-02-15

2281 The NAPstar family of NADP redox state sensors highlights glutathione as the primary mediator of anti-oxidative electron flux

Scherschel, M.; Niemeier, J.-O.; Jacobs, L.; Hoffmann, M.; Diederich, A.; Bell, C.; Hoehne, P.; Raetz, S.; Kroll, J.; Steinbeck, J.; Lichtenauer, S.; Multhoff, J.; Zimmermann, J.; Sadhanasatish, T.; Rothemann, R. A.; Grashoff, C.; Messens, J.; Ampofo, E.; Laschke, M. W.; Riemer, J.; Roma, L. P.; Schwarzlander, M.; Morgan, B.

10.1101/2024.02.14.580349 — biochemistry — Posted on 2024-02-15

2282 Breaking Barriers: pCF10 Type 4 Secretion System relies on a self-regulating muramidase to modulate the cell wall

Sun, W.-S.; Torrens, G.; ter Beek, J.; Cava, F.; Berntsson, R. P.-A.

10.1101/2024.02.15.580431 — biochemistry — Posted on 2024-02-15

2283 Gel-Assisted Proteome Position Integral Shift (GAPPIS) Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Novel Caspase 3 Substrates

Meng, Z.; Saei, A. A.; Zhang, X.; Lyu, H.; Gharibi, H.; Lundstrom, S. L.; Vegvari, A.; Gaetani, M.; Zubarev, R. A.

10.1101/2024.02.14.579877 — biochemistry — Posted on 2024-02-15

2284 Discovery of Alkenyl Oxindole as a Novel PROTAC Moiety for Targeted Protein Degradation via CRL4DCAF11 Recruitment

Wang, Y.; Wei, T.; Zhao, M.; Huang, A.; Sun, F.; Chen, L.; Lin, R.; Xie, Y.; Zhang, M.; Xu, S.; Sun, Z.; Hong, L.; Wang, R.; Tian, R.; Li, G.

10.1101/2024.02.15.580430 — biochemistry — Posted on 2024-02-15

2285 T cell interaction partners of DHHC20

Haxhiraj, D.; Kuropka, B.; Brencher, E.; Rosenberger, D.; Brandt, H.; Speck, D.; Scheerer, P.; Bruegger, B.; Clementi, C.; Freund, C.

10.1101/2024.02.14.580290 — biochemistry — Posted on 2024-02-15

2286 Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot

Aramburu, O.; Pardo, B. G.; Rodriguez-Villamayor, P.; Blanco Hortas, A.; Lamas, J.; Dewari, P. S.; Perojil, D.; Boudinot, P.; Macqueen, D. J.; Bouza, C.; Martinez, P.

10.1101/2024.02.15.580452 — genomics — Posted on 2024-02-15

2287 A missense variant effect map for the human tumour suppressor protein CHK2

Gebbia, M.; Zimmerman, D. I.; Jiang, R.; Nguyen, M.; Weile, J.; Li, R.; Gavac, M.; Kishore, N.; Sun, S.; Boonen, R. A.; Dines, J. N.; Wahl, A.; Reuter, J.; Johnson, B.; Fowler, D.; van Attikum, H.; Roth, F. P.

10.1101/2024.02.13.579700 — genetics — Posted on 2024-02-15

2288 Predictable functional biogeography of marine microbial heterotrophs

Zakem, E. J.; McNichol, J.; Weissman, J. L.; Raut, Y.; Xu, L.; Halewood, E. R.; Carlson, C. A.; Dutkiewicz, S.; Fuhrman, J. A.; Levine, N. M.

10.1101/2024.02.14.580411 — ecology — Posted on 2024-02-15

2289 Scalable and Efficient Generation of Mouse Primordial Germ Cell-like Cells

Ding, X.; Li, L.; Gao, J.; Yi, D.; Schimenti, J. C.

10.1101/2024.02.15.580543 — cell biology — Posted on 2024-02-15

2290 Myosin-19 and Miro regulate mitochondria-endoplasmatic reticulum contacts and mitochondria inner membrane architecture

Attia, A.; Majstrowicz, K.; Shembekar, S.; Honnert, U.; Nikolaus, P.; Lohman, B.; Baehler, M.

10.1101/2024.02.14.580241 — molecular biology — Posted on 2024-02-15

2291 Maternal and Neonatal Colonization with Multidrug Resistant and Extended Spectrum beta-Lactamase Producing Escherichia coli and Klebsiella pneumoniae in a Cameroonian Labour Ward

Njeuna, A.; Founou, L. L.; Founou Zangue, R. C.; Koudoum, P.; Mbossi, A.; Blocker, A.; Bentley, S. D.; Etame, L.

10.1101/2024.02.14.579597 — molecular biology — Posted on 2024-02-15

2292 A fungal metabolic regulator underlies infectious synergism during Candida albicans-Staphylococcus aureus intra-abdominal co-infection

Paul, S.; Todd, O. A.; Eichelberger, K. R.; Tkaczyk, C.; Sellman, B. R.; Noverr, M. C.; Cassat, J. E.; Fidel, P. L.; Peters, B. M.

10.1101/2024.02.15.580531 — microbiology — Posted on 2024-02-15

2293 In vitro activity of cefiderocol against carbapenemase-producing and meropenem-nonsusceptible gram-negative bacteria collected in the Japan Antimicrobial Resistant Bacterial Surveillance (JARBS-GNR)

Kayama, S.; Kawakami, S.; Kondo, K.; Kitamura, N.; Yu, L.; Hayashi, W.; Yahara, K.; Sugawara, Y.; Sugai, M.

10.1101/2024.02.14.580343 — microbiology — Posted on 2024-02-15

2294 Structural basis for activation and mechanism of the bacterial hexameric motors RadA and ComM in DNA branch migration during homologous recombination

Rosa, L. T.; Vernhes, E.; Soulet, a.-L.; Polard, P.; Fronzes, R.

10.1101/2024.02.15.580443 — microbiology — Posted on 2024-02-15

2295 Ligand binding determines proteolytic stability of Vibrio LuxR/HapR quorum sensing transcription factors

Rasal, T.; Mallery, C.; Brockley, M.; Brown, L.; Paczkowski, J.; van Kessel, J.

10.1101/2024.02.15.580527 — microbiology — Posted on 2024-02-15

2296 Photo-Uncaging Triggers on Self-Blinking to Control Single-Molecule Fluorescence Kinetics for Super-Resolution Imaging

Zheng, Y.; Ye, Z.; Zhang, X.; Xiao, Y.

10.1101/2024.02.13.580074 — biochemistry — Posted on 2024-02-15

2297 Optical Control of Cell-Surface and Endomembrane-Exclusive β-Adrenergic Receptor Signaling

Thotamune, W.; Ubeysinghe, S.; Shrestha, K. K.; Mostafa, M. E.; Young, M. C.; Karunarathne, A.

10.1101/2024.02.14.580335 — biochemistry — Posted on 2024-02-15

2298 Expanding the molecular grammar of polar residues and arginine in FUS prion-like domain phase separation and aggregation

Wake, N.; Weng, S.-L.; Zheng, T.; Wang, S.-H.; Kirilenko, V.; Mittal, J.; Fawzi, N. L.

10.1101/2024.02.15.580391 — biochemistry — Posted on 2024-02-15

2299 Structural and biochemical characterization of the mitomycin C repair exonuclease MrfB

Manthei, K. A.; Munson, L. M.; Nandakumar, J.; Simmons, L. A.

10.1101/2024.02.15.580553 — biochemistry — Posted on 2024-02-15

2300 LXA4 promotes the browning of white adipose through miR-133a-3p/SIRT1 pathway

Yu, D.; Ruan, Y.; Wang, Y.; Chen, X.; Wang, D.; Wu, T.

10.1101/2024.02.14.580287 — biochemistry — Posted on 2024-02-15

2301 Bioengineering secreted proteases converts divergent Rcr3 orthologs and paralogs into extracellular immune co-receptors

Kourelis, J.; Schuster, M.; Demir, F.; Mattinson, O.; Krauter, S.; Kahlon, P. S.; O'Grady, R.; Royston, S.; Bravo-Cazar, A. L.; Mooney, B. C.; Huesgen, P. F.; Kamoun, S.; van der Hoorn, R. A. L.

10.1101/2024.02.14.580413 — plant biology — Posted on 2024-02-15

2302 Decoding proteome functional information in model organisms using protein language models.

Barrios-Nunez, I.; Martinez-Redondo, G. I.; Medina-Burgos, P.; Cases, I.; Fernandez, R.; Rojas, A. M.

10.1101/2024.02.14.580341 — bioinformatics — Posted on 2024-02-15

2303 Transcription Factors with Broad Expression in the Zebrafish Spinal Cord

England, S. J.; Campbell, P.; Bates, R.; Grieb, G.; Fancher, W.; Lewis, K.

10.1101/2024.02.14.580357 — developmental biology — Posted on 2024-02-15

2304 Local variation in brain temperature explains gender-specificity of working memory performance

Rogala, J.; Dreszer, J.; Sinczuk, M.; Miciuk, Łukasz; Piatkowska-Janko, E.; Bogorodzki, P.; Wolak, T.; Wrobel, A.; Konarzewski, M.

10.1101/2024.02.14.580344 — neuroscience — Posted on 2024-02-15

2305 Cell Size Controls Photosynthetic Capacity in a Mesoamerican and an Andean Genotype of Phaseolus vulgaris L.

Egesa, A. O.; Vallejos, C. E.; Begcy, K.

10.1101/2024.02.13.580151 — physiology — Posted on 2024-02-15

2306 Thyroid Hormone Suppresses Medulloblastoma Progression Through Promoting Terminal Differentiation of Tumor Cells

Yang, Z.; Yang, Y.; Valdes-Rives, S. A.; Liu, Q.; Li, Y.; Tan, J.; Tan, Y.; Koch, C. A.; Rong, Y.; Houser, S. R.; Wei, S.; Cai, K.; Cheng, S.-y.; Curran, T.; Wechsler-Reya, R.

10.1101/2024.02.13.580111 — cancer biology — Posted on 2024-02-15

2307 Canine major histocompatibility complex class I (MHC-I) diversity landscape

Feng, Y.; Ho, K.-L.; Zhang, M.; Sundaresha, N. B.; Cavanagh, H. L.; Zhao, S.

10.1101/2024.02.14.580220 — bioinformatics — Posted on 2024-02-15

2308 pipesnake : Generalized software for the assembly and analysis of phylogenomic datasets from conserved genomic loci

Brennan, I. G.; Al Bkhetan, Z.; Singhal, S.

10.1101/2024.02.13.580223 — bioinformatics — Posted on 2024-02-15

2309 The De Bruijn Mapping Problem with Changes in the Graph

B. Rocha, L.; Adi, S. S.; Araujo, E.

10.1101/2024.02.15.580401 — bioinformatics — Posted on 2024-02-15

2310 Motif Interactions Affect Post-Hoc Interpretability of Genomic Convolutional Neural Networks

Lemanczyk, M. S.; Bartoszewicz, J. M.; Renard, B. Y.

10.1101/2024.02.15.580353 — bioinformatics — Posted on 2024-02-15

2311 A Multi-Dimensional Approach to Map Disease Relationships Challenges Classical Disease Views

Mobus, L.; Serra, A.; Fratello, M.; Pavel, A.; Federico, A.; Greco, D.

10.1101/2024.02.15.580369 — bioinformatics — Posted on 2024-02-15

2312 Klumpy: A tool to evaluate the integrity of long-read genome assemblies and illusive sequence motifs

Madrigal, G.; Minhas, B. F.; Catchen, J. M.

10.1101/2024.02.14.580330 — bioinformatics — Posted on 2024-02-15

2313 Recurrent loss of crossover interference punctuates the recombination landscape across yeast species

Dutta, A.; Dutreux, F.; Garin, M.; Caradec, C.; Friedrich, A.; Brach, G.; Thiele, P.; llorente, b.; Schacherer, J.

10.1101/2024.02.13.580081 — genomics — Posted on 2024-02-15

2314 UBA1-CDK16: A Sex-Specific Chimeric RNA and Its Role in Immune Sexual Dimorphism

Shi, X.; Facemire, L.; Singh, S.; Kumar, S.; Cornelison, R.; Liang, C.; Qin, F.; Liu, A.; Lin, S.; Tang, Y.; Elfman, J.; Manley, T.; Bullock, T.; Haverstick, D.; Wu, P.; Li, H.

10.1101/2024.02.13.580120 — genomics — Posted on 2024-02-15

2315 Inferring a role for programmed cell death during the origin and evolution of wing polyphenism in ants

Abouheif, E.; Hanna, L.; Boudinot, B.; Liebig, J.

10.1101/2024.02.14.580404 — evolutionary biology — Posted on 2024-02-15

2316 Long-range chemical signalling in vivo is regulated by mechanical signals

Pillai, E. K.; Mukherjee, S.; Gampl, N.; McGinn, R. J.; Mooslehner, K. A.; Thompson, A. J.; Franze, K.

10.1101/2024.02.15.580459 — developmental biology — Posted on 2024-02-15

2317 Addressing Artemisinin Resistance in Malaria Treatment: A Novel Ferrous ACT (FACT) Formulation

Wang, Y.; Tang, K.

10.1101/2024.02.15.579727 — cell biology — Posted on 2024-02-15

2318 SARS-CoV-2 serosurvey of healthy, privately owned cats presenting to a New York City animal hospital in the early phase of the COVID-19 pandemic (2020-2021)

Choi, A.; Stout, A. E.; Rollins, A.; Wang, K.; Guo, Q.; Jaimes, J. A.; Kennedy, M.; Wagner, B.; Whittaker, G. R.

10.1101/2024.02.13.580068 — microbiology — Posted on 2024-02-15

2319 A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

Metzdorf, K.; Jacobsen, H.; Kim, Y.; Teixeira Alves, L. G.; Kulkarni, U.; Eschke, K.; Chaudhry, M. Z.; Hoffmann, M.; Bertoglio, F.; Ruschig, M.; Hust, M.; Brdovcak, M. C.; Materljan, J.; Sustic, M.; Krmpotic, A.; Jonjic, S.; Widera, M.; Ciesek, S.; Poehlmann, S.; Landthaler, M.; Cicin-Sain, L.

10.1101/2022.11.25.517953 — immunology — Posted on 2024-02-15

2320 Fraudulent studies are undermining the reliability of systematic reviews - a study of the prevalence of problematic images in preclinical studies of depression

Berrio, J. P.; Kalliokoski, O.

10.1101/2024.02.13.580196 — neuroscience — Posted on 2024-02-15

2321 Adeno-associated viruses for efficient gene expression in the axolotl nervous system

Lust, K.; Tanaka, E. M.

10.1101/2024.02.15.580426 — neuroscience — Posted on 2024-02-15

2322 Neural Circuit Revision in Retinal Remodeling, A Pathoconnectomics Approach

Pfeiffer, R. L.; Dahal, J.; Sigulinsky, C. L.; Anderson, J. R.; Barrera, I. A.; Yang, J.-H.; Haddadin, O.; Houser, A. R.; Garcia, J. C.; Jones, B. W.

10.1101/2024.02.14.580149 — neuroscience — Posted on 2024-02-15

2323 Functional specialization of Arabidopsis VEL polymerization domains in the switch to Polycomb silencing

Schulten, A.; Jang, G.-J.; Payne-Dwyer, A.; Nielsen, M. L.; Bienz, M.; Leake, M. C.; Dean, C.

10.1101/2024.02.15.580496 — plant biology — Posted on 2024-02-15

2324 A systematic quantitative approach comprehensively defines domain-specific functional pathways linked to Schizosaccharomyces pombe heterochromatin regulation

Muhammad, A.; Sarkadi, Z.; van Emden, T. S.; Mazumder, A.; Capella, M.; Fekete, G.; Sreechakram, V. N. S.; Al-Sady, B.; Papp, B.; Barrales, R. R.; Braun, S. J.

10.1101/2024.02.13.579970 — genomics — Posted on 2024-02-15

2325 Overcoming the "feast or famine" effect: improved interaction testing in genome-wide association studies

Zhou, H.; McPeek, M. S.

10.1101/2024.02.13.580168 — genetics — Posted on 2024-02-15

2326 Potent pollen gene regulation by DNA glycosylases in maize

Zeng, Y.; Somers, J.; Bell, H. S.; Dawe, R. K.; Fowler, J. E.; Nelms, B.; Gent, J. I.

10.1101/2024.02.13.580204 — genetics — Posted on 2024-02-15

2327 The Tofu mutation restores female fertility to Drosophila with a null BEAF mutation

McKowen, J. K.; Dassanayake, M.; Hart, C. M.

10.1101/2024.02.13.580197 — genetics — Posted on 2024-02-15

2328 PRS-Net: Interpretable polygenic risk scores via geometric learning

Li, H.; Zeng, J.; Snyder, M.; Zhang, S.

10.1101/2024.02.13.580211 — genetics — Posted on 2024-02-15

2329 Leaf functional trait evolution and its putative climatic drivers in African Coffea species

Hendrickx, A.; Hatangi, Y.; Honnay, O.; Janssens, S. B.; Stoffelen, P.; Vandelook, F.; Depecker, J.

10.1101/2024.02.13.580072 — evolutionary biology — Posted on 2024-02-15

2330 Phylotranscriptomics reveals convergent behavioral evolution associated with shared and unique mechanisms in cavity-nesting songbirds

Lipshutz, S. E.; Hibbins, M. S.; Bentz, A. B.; Buechlin, A. M.; Empson, T. A.; George, E. M.; Hauber, M. E.; Rusch, D. B.; Schelsky, W. M.; Thomas, Q. K.; Torneo, S. J.; Turner, A. M.; Wolf, S. E.; Woodruff, M. J.; Hahn, M. W.; Rosvall, K. A.

10.1101/2024.02.13.580205 — evolutionary biology — Posted on 2024-02-15

2331 Multiple horizontal mini-chromosome transfers drive genome evolution of clonal blast fungus lineages

Barragan, A. C.; Latorre, S. M.; Malmgren, A.; Harant, A.; Win, J.; Sugihara, Y.; Burbano, H. A.; Kamoun, S.; Langner, T.

10.1101/2024.02.13.580079 — evolutionary biology — Posted on 2024-02-15

2332 Evolutionary genomics reveals variation in structure and genetic content implicated in virulence and lifestyle in the genus Gaeumannomyces

Hill, R.; Grey, M.; Olivera Fedi, M.; Smith, D. P.; Ward, S. J.; Canning, G.; Irish, N.; Smith, J.; McMillan, V.; Hammond, J.; Osborne, S.-J.; Chancellor, T.; Swarbreck, D.; Hall, N.; Palma-Guerrero, J.; Hammond-Kosack, K. E.; McMullan, M.

10.1101/2024.02.15.580261 — evolutionary biology — Posted on 2024-02-15

2333 Predicting fitness related traits using gene expression and machine learning

Henry, G. A.; Stinchcombe, J. R.

10.1101/2024.02.14.580307 — evolutionary biology — Posted on 2024-02-15

2334 Genetic Mechanisms underlying Preference-Performance Mismatches: Insights from a Specialized Native Herbivore on an Invasive Toxic Plant

Ravikanthachari, N.; Boggs, C. L.

10.1101/2024.02.14.580222 — evolutionary biology — Posted on 2024-02-15

2335 Emergence of saliva protein genes in the secretory calcium-binding phosphoprotein (SCPP) locus and accelerated evolution in primates

Pajic, P.; Landau, L.; Gokcumen, O.; Ruhl, S.

10.1101/2024.02.14.580359 — evolutionary biology — Posted on 2024-02-15

2336 Muller's Ratchet in Action: The Erosion of Sexual Reproduction Genes in Domesticated Cassava (Manihot esculenta)

Long, E. M.; Stitzer, M. C.; Monier, B.; Schulz, A. J.; Romay, C.; Robbins, K.; Buckler, E. S.

10.1101/2024.02.14.580345 — evolutionary biology — Posted on 2024-02-15

2337 High-throughput investigation of genetic design constraints in domesticated Influenza A Virus for transient gene delivery

Sychla, A.; Stach, C.; Roach, S.; Hayward, A.; Langlois, R. A.; Smanski, M.

10.1101/2024.02.14.580300 — bioengineering — Posted on 2024-02-15

2338 Decision support for managing an invasive pathogen through efficient clean seed systems: Cassava mosaic disease in Southeast Asia

Andersen Onofre, K.; Delaquis, E.; Newby, J.; de Haan, S.; Thuy, C. T. L.; Minato, N.; Legg, J.; Cuellar, W.; Alcala Briseno, R.; Garrett, K. A.

10.1101/2024.02.13.580210 — ecology — Posted on 2024-02-15

2339 Dispersal and gene flow in anadromous salmonids: a systematic review

Lamarins, A.; Buoro, M.

10.1101/2024.02.15.580427 — ecology — Posted on 2024-02-15

2340 Exploring biodiversity dynamics and taxonomy of Rubiaceae fungal endophytes in tropical regions

Castillo-Gonzalez, H.; Slot, J. C.; Yarwood, S.; Chaverri, P.

10.1101/2024.02.13.580172 — ecology — Posted on 2024-02-15

2341 Intraspecific diversity in thermal performance determines phytoplankton ecological niche

Krinos, A. I.; Shapiro, S. K.; Li, W.; Haley, S. T.; Dyhrman, S. T.; Dutkiewicz, S.; Follows, M. J.; Alexander, H.

10.1101/2024.02.14.580366 — ecology — Posted on 2024-02-15

2342 Eph/ephrin signalling in the developing brain is regulated by tissue stiffness

Sipkova, J.; Franze, K.

10.1101/2024.02.15.580461 — developmental biology — Posted on 2024-02-15

2343 Characterization of Reconstructed Human Epidermis in a Chemically-defined, Animal Origin-free Cell Culture System

Bajsert, J.; De Glas, V.; Faway, E.; Lambert de Rouvroit, C.; Perez-Aso, M.; Cook, P. W.; Poumay, Y.

10.1101/2024.02.13.580080 — cell biology — Posted on 2024-02-15

2344 A ratiometric ER calcium sensor for quantitative comparisons across cell types and subcellular regions

Farrell, R. J.; Bredvik, K. G.; Hoppa, M. B.; Hinnegan, S. T.; Brown, T. A.; Ryan, T. A.

10.1101/2024.02.15.580492 — cell biology — Posted on 2024-02-15

2345 Current research on epigenetic age and cellular senescence: a bibliometric and visual analysis

kahaer, M.; Aikeremu, D.; Wang, H.; Xu, K.; Sun, Z.

10.1101/2024.02.13.580124 — cell biology — Posted on 2024-02-15

2346 Truncated NLRC5 isoforms in human placenta: expression, regulation by miR-218-5p, and function in trophoblasts

Shan, Y.; O'Brian, J.; Nadeem, L.; Dunk, C.; Chen, Y.; Brkic, J.; Hayder, H.; Lye, S. J.; Peng, C.

10.1101/2024.02.13.580136 — cell biology — Posted on 2024-02-15

2347 Characterization of a new lacrimal gland cell line in 2D and 3D cell culture models

Gleixner, S.; Zahn, I.; Dietrich, J.; Singh, S.; Drobny, A.; Schneider, Y.; Schwendner, R.; Socher, E.; Blavet, N.; Brauer, L.; Gostian, A.-O.; Balk, M.; Schulze-Tanzil, G.; Gunther, C.; Paulsen, F.; Arnold, P.

10.1101/2024.02.13.580096 — cell biology — Posted on 2024-02-15

2348 Cathepsin B regulates ovarian reserve quality and quantity via mitophagy by modulating IGF1R turnover.

Mohanty, A.; Kumari, A.; Kumar. S, L.; Kumar, A.; Birajdar, P.; Beniwal, R.; Athar, M.; Kumar P, K.; Prasada Rao, H.

10.1101/2024.02.14.580410 — cell biology — Posted on 2024-02-15

2349 Toxicity of the model protein 3xGFP arises from degradation overload, not from aggregate formation

Namba, S.; Moriya, H.

10.1101/2024.02.14.580286 — cell biology — Posted on 2024-02-15

2350 Isolation of small extracellular vesicles from regenerating muscle tissue using Tangential Flow Filtration and Size Exclusion Chromatography

Gurriaran-Rodriguez, U.; Rudnicki, M. A.

10.1101/2024.02.14.580358 — cell biology — Posted on 2024-02-15

2351 Exact centriole counts are critical for B cell development but not function

Schapfl, M. A.; LoMastro, G. M.; Braun, V. Z.; Hirai, M.; Levine, M. S.; Kiermaier, E.; Labi, V.; Holland, A. J.; Villunger, A.

10.1101/2024.02.14.580240 — cell biology — Posted on 2024-02-15

2352 SOCS domain targets ECM assembly in lung fibroblasts and experimental lung fibrosis

Magdaleno, C.; Tschumperlin, D.; Rajasekaran, N.; Varadaraj, A.

10.1101/2024.02.14.580347 — cell biology — Posted on 2024-02-15

2353 The transmembrane protein Syndecan regulates stem cell nuclear properties and cell maintenance.

Eldridge-Thomas, B. L.; Bohere, J. G.; Roubinet, C.; Barthelemy, A.; Samuels, T. J.; Karam Teixeira, F.; Kolahgar, G.

10.1101/2024.02.15.580237 — cell biology — Posted on 2024-02-15

2354 A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope

Mannino, P. J.; Perun, A.; Surovstev, I.; Ader, N. R.; Shao, L.; Melia, T.; King, M. C.; Lusk, C. P.

10.1101/2024.02.14.580336 — cell biology — Posted on 2024-02-15

2355 Derepression of transposable elements enhances interferon beta signaling and stem/progenitor cell activity after proton irradiation.

Cinat, D.; van der Wal, R.; Baanstra, M.; Gamez, A. A. S.; Jellema-de Bruin, A.; van Goethem, M.-J.; van Vugt, M.; Barazzuol, L.; Coppes, R. P.

10.1101/2024.02.14.580306 — cell biology — Posted on 2024-02-15

2356 Apicoplast-derived isoprenoids are essential for biosynthesis of GPI protein anchors, and consequently for egress and invasion in Plasmodium falciparum

Bulloch, M. S.; Huynh, L. K.; Kennedy, K.; Ralton, J. E.; McConville, M. J.; Ralph, S. A.

10.1101/2024.02.14.580402 — cell biology — Posted on 2024-02-15

2357 Immune escape of Omicron lineages BA.1, BA.2, BA.5.1, BQ.1, XBB.1.5, EG.5.1 and JN.1.1 after vaccination, infection and hybrid immunity

Bekliz, M.; Essaidi-Laziosi, M.; Adea, K.; Hosszu-Fellous, K.; Alvarez, C.; Bellon, M.; Sattonnet-Roche, P.; Puhach, O.; Dbeissi, D.; Zaballa, M. E.; Stringhini, S.; Guessous, I.; Vetter, P.; Eberhardt, C. S.; Kaiser, L.; Eckerle, I.

10.1101/2024.02.14.579654 — microbiology — Posted on 2024-02-15

2358 Emergence and spread of SARS-CoV-2 variants from farmed mink to humans and back during the epidemic in Denmark, June-November 2020.

Rasmussen, T. B.; Qvesel, A. G.; Pedersen, A. G.; Olesen, A. S.; Fonager, J.; Rasmussen, M.; Sieber, R. N.; Stegger, M.; Artavia, F. F. C.; Thuesen, E. R.; Goedknegt, M. J. F.; Lohse, L.; Mortensen, S.; Fomsgaard, A.; Boklund, A. E.; Botner, A.; Belsham, G. J.

10.1101/2024.02.13.580053 — microbiology — Posted on 2024-02-15

2359 A Broad-Spectrum Multi-Antigen mRNA/LNP-Based Pan-Coronavirus Vaccine Induced Potent Cross-Protective Immunity Against Infection and Disease Caused by Highly Pathogenic and Heavily Spike-Mutated SARS-CoV-2 Variants of Concern in the Syrian Hamster Model

Prakash, S.; Dhanushkodi, N. R.; Singer, M.; Quadiri, A.; Zayou, L.; Vahed, H.; Coulon, P.-G.; El Babsiri, A.; Gil, D.; Ulmer, J. B.; BENMOHAMED, L.

10.1101/2024.02.14.580225 — immunology — Posted on 2024-02-15

2360 Presynaptic Nrxn3 is essential for ribbon-synapse assembly in hair cells

Jukic, A.; Lei, Z.; Cebul, E. R.; Pinter, K.; Mosqueda, N.; David, S.; Tarchini, B.; Kindt, K. S.

10.1101/2024.02.14.580267 — neuroscience — Posted on 2024-02-15

2361 Multi-species community platform for comparative neuroscience in teleost fish

10.1101/2024.02.14.580400 — neuroscience — Posted on 2024-02-15

2362 Genome sequence of the medicinal and ornamental plant Digitalis purpurea reveals the molecular basis of flower color variation

Wolff, K.; Friedhoff, R.; Horz, J. M.; Pucker, B.

10.1101/2024.02.14.580303 — plant biology — Posted on 2024-02-15

2363 Thermally activated antibiotic production by probiotic bacteria for pathogen elimination

Dey, S.; Seyfert, C. E.; Fink-Straube, C.; Kany, A. M.; Mueller, R.; Sankaran, S.

10.1101/2024.02.13.579303 — bioengineering — Posted on 2024-02-15

2364 DNDesign: Enhancing Physical Understanding of Protein Inverse Folding Model via Denoising

Lee, Y.; Kim, J.

10.1101/2023.12.05.570298 — biochemistry — Posted on 2024-02-15

2365 Differentiation smelling footprints of the Chagas disease vector using an electronic nose based on artificial intelligence algorithms

Ruiz, L. F.; Sierra, D. A.; Ortega, H.; Rincon-Orozco, B.; Duque, J. E.

10.1101/2024.02.13.579939 — animal behavior and cognition — Posted on 2024-02-15

2366 Anthropogenic noise affects vocalisation properties of the territorial song of Western Australian magpies

Blackburn, G.; Dutour, M.; Ashton, B. J.; Thornton, A.; Ridley, A. R.

10.1101/2024.02.15.578887 — animal behavior and cognition — Posted on 2024-02-15

2367 Estimating Genome-wide Phylogenies Using Probabilistic Topic Modeling

Khodaei, M.; Edwards, S. V.; Beerli, P.

10.1101/2023.12.20.572577 — evolutionary biology — Posted on 2024-02-15

2368 TSC22D, WNK and NRBP gene families exhibit functional buffering and evolved with Metazoa for macromolecular crowd sensing

Xiao, Y.-X.; Lee, S. Y.; Uribe, M. A.; Samson, R.; Au, A.; Yukti, K.; Liu, Z.; Cheng, R.; Aulakh, K.; Wei, J.; Farias, A. G.; Reilly, T.; Habsid, A.; Brown, K.; Chan, K.; Mero, P.; Huang, J. Q.; Billmann, M.; Rahman, M.; Myers, C.; Andrews, B.; Youn, J.-Y.; Yip, C.; Rotin, D.; Derry, B.; Forman-Kay, J.; moses, a.; Iva, P.; Gingras, A. C.; Moffat, J.

10.1101/2024.02.13.579840 — cell biology — Posted on 2024-02-15

2369 In-situ architecture of the human prohibitin complex

Lange, F.; Ratz, M.; Dohrke, J.-N.; Wenzel, D.; Ilgen, P.; Riedel, D.; Jakobs, S.

10.1101/2024.02.14.579514 — cell biology — Posted on 2024-02-15

2370 DFCP1 is a Regulator of ATGL-mediated Lipid Droplet Lipolysis

Ismail, V.; Schuetz, M.; Castillo-Badillo, J.; Naismith, T.; Kast, D. J.

10.1101/2024.02.14.580382 — cell biology — Posted on 2024-02-15

2371 HIV-1 Mediated Cortical Actin Disruption Mirrors ARP2/3 Defects Found in Primary T Cell Immunodeficiencies.

Crater, J. M.; Dunn, D. C.; Nixon, D. F.; O'Brien, R. L. F.

10.1101/2023.07.27.550856 — immunology — Posted on 2024-02-15

2372 Reliance on self-reports and estimated food composition data in nutrition research introduces significant bias that can only be addressed with biomarkers

Ottaviani, J. I.; Sagi-Kiss, V.; Schroeter, H.; Kuhnle, G. G. C.

10.1101/2023.10.26.564308 — physiology — Posted on 2024-02-15

2373 Advancing Transcription Factor Binding Site Prediction Using DNA Breathing Dynamics and Sequence Transformers via Cross Attention

Kabir, A.; Bhattarai, M.; Rasmussen, K. O.; Shehu, A.; Bishop, A. R.; Alexandrov, B. S.; Usheva, A.

10.1101/2024.01.16.575935 — bioinformatics — Posted on 2024-02-15

2374 Chlamydomonas cells transition through distinct Fe nutrition stages within 48 h of transfer to Fe-free medium

Liu, H. W.; Urzica, E. I.; Gallaher, S. D.; Blaby-Haas, C. E.; Iwai, M.; Schmollinger, S.; Merchant, S. S.

10.1101/2024.02.13.579691 — plant biology — Posted on 2024-02-15

2375 Leaf abaxial and adaxial surfaces differentially affect plant-fungal pathogen interactions

Caseys, C.; Muhich, A. J.; Vega, J.; Ahmed, M.; Hopper, A.; Kelly, D.; Kim, S.; Madrone, M.; Plaziak, T.; Wang, M.; Kliebenstein, D.

10.1101/2024.02.13.579726 — plant biology — Posted on 2024-02-15

2376 Greater leaf photosynthesis in the field by increasing mesophyll conductance via modified cell wall porosity and thickness in tobacco

Salesse-Smith, C. E.; Lochocki, E. B.; Doran, L.; Haas, B. E.; Stutz, S. S.; Long, S. P.

10.1101/2024.02.13.580201 — plant biology — Posted on 2024-02-15

2377 The ELF3-BBX24/BBX25-PIF4 module controls thermosensory growth in Arabidopsis

Malakar, B. C.; Singh, S.; Garhwal, V.; Upadhyaya, G.; Chandramohan, R.; Gangappa, S. N.

10.1101/2024.02.14.580362 — plant biology — Posted on 2024-02-15

2378 In vitro function, assembly, and interaction of primary cell wall cellulose synthase homotrimers

Pallinti, P.; Ho, R.; Zimmer, J.

10.1101/2024.02.13.580128 — plant biology — Posted on 2024-02-15

2379 Silencing of a raspberry homologue of VRN1 is associated with disruption of dormancy induction and misregulation of subsets of dormancy-associated genes.

Mateos, B.; Preedy, K.; Milne, L.; Morris, J.; Hedley, P. E.; Simpson, C. G.; Hancock, R. D.; Graham, J.

10.1101/2024.02.13.580140 — plant biology — Posted on 2024-02-15

2380 Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins

Milferstaedt, S. W. L.; Joest, M.; Hoernstein, S. N. W.; Bohlender, L. L.; Oezdemir, B.; van der Does, C.; Decker, E. L.; Reski, R.

10.1101/2024.02.14.580282 — plant biology — Posted on 2024-02-15

2381 Herbarium specimens reveal links between Capsella bursa-pastoris leaf shape and climate

Hightower, A. T.; Chitwood, D. H.; Josephs, E. B.

10.1101/2024.02.13.580180 — plant biology — Posted on 2024-02-15

2382 Cross-tolerance evolution is driven by selection on heat tolerance in Drosophila subobscura

Castaneda, L. E.

10.1101/2023.09.05.556367 — evolutionary biology — Posted on 2024-02-15

2383 Cell2Sentence: Teaching Large Language Models the Language of Biology

Levine, D.; Rizvi, S. A.; Levy, S.; Pallikkavaliyaveetil, N.; Chen, X.; Zhang, D.; Ghadermarzi, S.; Wu, R.; Zhang, Z.; Vrkic, I.; Zhong, A.; Raskin, D.; Han, I.; Fonseca, A.; Ortega Caro, J.; Karbasi, A.; Dhodapkar, R. M.; van Dijk, D.

10.1101/2023.09.11.557287 — bioinformatics — Posted on 2024-02-15

2384 Ultra-sensitive water contaminant detection with transcription factor interfaced microcantilevers

Agarwal, D. K.; Lucci, T. J.; Jung, J. K.; Shekhawat, G. S.; Lucks, J. B.; Dravid, V. P. B.

10.1101/2024.02.01.578376 — synthetic biology — Posted on 2024-02-15

2385 Quick and effective approximation of in silico saturation mutagenesis experiments with first-order Taylor expansion

Sasse, A.; Chikina, M.; Mostafavi, S.

10.1101/2023.11.10.566588 — bioinformatics — Posted on 2024-02-15

2386 A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine

Walton, B. L.; Shattuck-Brandt, R.; Hamann, C. A.; Tung, V. W.; Colazo, J. M.; Brand, D. D.; Hasty, K. A.; Duvall, C. L.; Brunger, J. M.

10.1101/2024.01.31.578281 — bioengineering — Posted on 2024-02-15

2387 A genetically-encoded fluorescent biosensor for visualization of acetyl-CoA in live cells

Smith, J. J.; Valentino, T. R.; Ablicki, A. H.; Banerjee, R.; Colligan, A. R.; Eckert, D. M.; Desjardins, G. A.; Diehl, K. L.

10.1101/2023.12.31.573774 — biochemistry — Posted on 2024-02-15

2388 Going with the flow: evidence for phenotypic variation in cooperative plasticity during predator inspection in Trinidadian guppies (Poecilia reticulata)

Dimitriadou, S.; Padget, R. F. B.; Jack, T.; Darden, S. K.

10.1101/2023.11.01.565091 — animal behavior and cognition — Posted on 2024-02-15

2389 Quantitative pathogenicity and host adaptation in a fungal plant pathogen revealed by whole-genome sequencing

AMEZROU, R.; DUCASSE, A.; COMPAIN, J.; LAPALU, N.; PITARCH, A.; DUPONT, L.; CONFAIS, J.; GOYEAU, H.; KEMA, G. H.; CROLL, D.; AMSELEM, J.; SANCHEZ-VALLET, A.; MARCEL, T. C.

10.1101/2022.12.23.521735 — genomics — Posted on 2024-02-15

2390 Computationally efficient demographic history inference from allele frequencies with supervised machine learning

Tran, L. N.; Sun, C. K.; Struck, T. J.; Sajan, M.; Gutenkunst, R. N.

10.1101/2023.05.24.542158 — genomics — Posted on 2024-02-15

2391 Integrated multimodal cell atlas of Alzheimer's disease

Gabitto, M. I.; Travaglini, K. J.; Rachleff, V. M.; Kaplan, E. S.; Long, B.; Ariza, J.; Ding, Y.; Mahoney, J. T.; Dee, N.; Goldy, J.; Melief, E. J.; Agrawal, A.; Kana, O.; Zhen, X.; Barlow, S. T.; Brouner, K.; Campos, J.; Campos, J.; Carr, A. J.; Casper, T.; Chakrabarty, R.; Clark, M.; Cool, J.; Dalley, R.; Darvas, M.; Ding, S.-L.; Dolbeare, T.; Egdorf, T.; Esposito, L.; Ferrer, R.; Fleckenstein, L. E.; Gala, R.; Gary, A.; Gelfand, E.; Gloe, J.; Guilford, N.; Guzman, J.; Hirschstein, D.; Ho, W.; Hupp, M.; Jarksy, T.; Johansen, N.; Kalmbach, B. E.; Keene, L. M.; Khawand, S.; Kilgore, M.; Kirkla

10.1101/2023.05.08.539485 — genomics — Posted on 2024-02-15

2392 Cost-Effective Approaches to Elucidate Intergeneric Relationships of Plants: Utilizing Multiple Conserved Nuclear Genes and Whole Chloroplast Genomes

Witharana, E. P.; San, M. H.; Jayawardana, N. U.; Kotoda, N.; Yamamoto, M.; Nagano, Y.

10.1101/2024.01.15.575800 — genomics — Posted on 2024-02-15

2393 Identification and characterization of intermediate states in mammalian neural crest cell epithelial to mesenchymal transition and delamination

Zhao, R.; Moore, E. L.; Gogol, M. M.; Unruh, J. R.; Yu, Z.; Peak, A.; Wang, Y.; Rajendran, N. K.; Trainor, P. A.

10.1101/2023.10.26.564204 — developmental biology — Posted on 2024-02-15

2394 Comparative transcriptomics reveal a novel tardigrade specific DNA binding protein induced in response to ionizing radiation

Anoud, M.; Delagoutte, E.; Helleu, Q.; Brion, A.; Duvernois-Berthet, E.; As, M.; Marques, X.; Lamribet, K.; Senamaud, C.; Jourdren, L.; Adrait, A.; Heinrich, S.; Toutirais, G.; Hamlaoui, S.; Gropplero, G.; Ponger, L.; Geze, M.; Blugeon, C.; Coute, Y.; Guidetti, R.; Rebecchi, L.; Giovannangeli, C.; De Cian, A.; Concordet, J.-P.

10.1101/2023.09.08.556854 — molecular biology — Posted on 2024-02-15

2395 Influence of insulin sensitivity on food cue evoked functional brain connectivity in children

Semeia, L.; Veit, R.; Zhao, S.; Luo, S.; Angelo, B.; Birkenfeld, A. L.; Preissl, H.; Xiang, A. H.; Kullmann, S.; Page, K. A.

10.1101/2024.02.12.579924 — neuroscience — Posted on 2024-02-15

2396 Reorganization of structural connectivity in the brain supports preservation of cognitive ability in healthy aging

Neudorf, J.; Shen, K.; McIntosh, A. R.

10.1101/2023.10.25.564045 — neuroscience — Posted on 2024-02-15

2397 Chronic activation of a negative engram induces behavioral and cellular abnormalities

Jellinger, A. L.; Suthard, R. L.; Yuan, B.; Surets, M.; Ruesch, E. A.; Caban, A. J.; Liu, X. S.; Shpokayte, M.; Ramirez, S.

10.1101/2023.11.15.567268 — neuroscience — Posted on 2024-02-15

2398 No evidence in favour of the existence of 'intentional' binding

Kong, G.; Aberkane, C.; Desoche, C.; Farne, A.; Vernet, M.

10.1101/2023.02.06.526214 — neuroscience — Posted on 2024-02-15

2399 M2M-InvNet: Human Motor Cortex Mapping from Multi-Muscle Response Using TMS and Generative 3D Convolutional Network

Akbar, M. N.; Yarossi, M.; Rampersad, S.; Lockwood, K.; Masoomi, A.; Tunik, E.; Brooks, D.; Erdogmus, D.

10.1101/2022.07.22.501062 — neuroscience — Posted on 2024-02-15

2400 Psilocybin induces dose-dependent changes in functional network organization in rat cortex

Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Mashour, G. A.; Vanini, G.; Pal, D.

10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-15

2401 A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level

Lalun, V. O.; Breiden, M.; Galindo-Trigo, S.; Smakowska-Luzan, E.; Simon, R.; Butenko, M. A.

10.1101/761346 — plant biology — Posted on 2024-02-15

2402 A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development

Edwards, A. K.; Chiurazzi, M. J.; Blaakmeer, A.; Vittozzi, Y.; Sharma, A.; Matton, S.; Kruusvee, V.; Straub, D.; Sessa, G.; Carabelli, M.; Morelli, G.; Wenkel, S.

10.1101/2024.02.01.578400 — plant biology — Posted on 2024-02-15

2403 Contrasted reaction norms of wheat yields in pure versus mixed stands explained by tillering plasticities and shade avoidance

Gawinowski, M.; Enjalbert, J.; Cournede, P.-H.; Flutre, T.

10.1101/2022.10.27.514050 — plant biology — Posted on 2024-02-15

2404 Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem

Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lou, Q.; Zhou, Z. H.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.

10.1101/2023.11.29.569229 — bioengineering — Posted on 2024-02-15

2405 Expanding the Drosophila toolkit for dual control of gene expression

Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.

10.1101/2023.08.15.553399 — genetics — Posted on 2024-02-15

2406 Catching more air: A method to spatially quantify aerial triazole resistance in Aspergillus fumigatus

Kortenbosch, H. H.; van Leuven, F.; van den Heuvel, C.; Schoustra, S. S.; Zwaan, B. J.; Snelders, E.

10.1101/2022.11.03.515058 — microbiology — Posted on 2024-02-15

2407 Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy

Ribis, J. W.; Nieto-Acuna, C. A.; Dong, Q.; DiBenedetto, N.; Mehra, A.; Nagawa, I. L.; El Meouche, I.; Aldridge, B. B.; Dunlop, M. J.; Tamayo, R.; Singh, A.; Shen, A.

10.1101/2024.02.13.580212 — microbiology — Posted on 2024-02-15

2408 Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma

Joulia, R.; Puttur, F.; Stölting, H.; Entwistle, L. J.; Voitovich, A.; Al-Sahaf, M.; Bonner, K.; Scotney, E.; Molyneaux, P.; Hewitt, R. J.; Walker, S. A.; Yates, L. L.; Saglani, S.; Lloyd, C. M.

10.1101/2023.03.07.529253 — immunology — Posted on 2024-02-15

2409 Distinct hippocampal mechanisms support concept formation and updating

Mack, M. L.; Love, B. C.; Preston, A. R.

10.1101/2024.02.14.580181 — neuroscience — Posted on 2024-02-15

2410 Scaling Properties for Artificial Neural Network Models of a Small Nervous System

Simeon, Q.; Venancio, L. R.; Yang, G.; Boyden, E. S.; Nayebi, A.

10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-02-15

2411 Two distinct mechanisms for Nav1.7 null analgesia

Kanellopoulos, A.; Tian, N.; Cox, J. J.; Zhao, J.; Woods, G.; Wood, J.

10.1101/2024.02.12.579826 — neuroscience — Posted on 2024-02-15

2412 Fractal cycles of sleep: a new aperiodic activity-based definition of sleep cycles

Rosenblum, Y.; Jafarzadeh Esfahani, M.; Adelhöfer, N.; Zerr, P.; Furrer, M.; Huber, R.; Steiger, A.; Zeising, M.; Horvath, C. G.; Schneider, B.; Bodizs, R.; Dresler, M.

10.1101/2023.07.04.547323 — neuroscience — Posted on 2024-02-15

2413 Multi-study fMRI outlooks on subcortical BOLD responses in the stop-signal paradigm

Isherwood, S. J. S.; Kemp, S. A.; Miletic, S.; Stevenson, N.; Bazin, P.-L.; Forstmann, B.

10.1101/2023.06.06.543900 — neuroscience — Posted on 2024-02-15

2414 Local muscle pressure stimulates the principal receptors for proprioception

Torell, F.; Dimitriou, M.

10.1101/2024.02.06.579058 — neuroscience — Posted on 2024-02-15

2415 Self-perceived middle-distance race pace is faster in Advanced Footwear Technology spikes

Bertschy, M.; Rodrigo Carranza, V.; Wilkie, E. W. C.; Healey, L. A.; Noble, J.; Albert, W. J.; Hoogkamer, W.

10.1101/2023.10.25.564056 — physiology — Posted on 2024-02-15

2416 mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

Bischof, H.; Maier, S.; Koprowski, P.; Kulawiak, B.; Burgstaller, S.; Jasinska, J.; Serafimov, K.; Zochowska, M.; Gross, D.; Schroth, W.; Matt, L.; Juarez Lopez, D. A.; Zhang, Y.; Bonzheim, I.; Büttner, F. A.; Fend, F.; Schwab, M.; Birkenfeld, A. L.; Malli, R.; Lämmerhofer, M.; Bednarczyk, P.; Szewczyk, A.; Lukowski, R.

10.1101/2023.10.02.560571 — cancer biology — Posted on 2024-02-15

2417 SpaCeNet: Spatial Cellular Networks from omics data

Schrod, S.; Lück, N.; Lohmayer, R.; Solbrig, S.; Völkl, D.; Wipfler, T.; Shutta, K. H.; Guebila, M. B.; Schäfer, A.; Beissbarth, T.; Zacharias, H. U.; Oefner, P. J.; Quackenbush, J.; Altenbuchinger, M.

10.1101/2022.09.01.506219 — bioinformatics — Posted on 2024-02-15

2418 Movi: a fast and cache-efficient full-text pangenome index

Zakeri, M.; Brown, N. K.; Ahmed, O. Y.; Gagie, T.; Langmead, B.

10.1101/2023.11.04.565615 — bioinformatics — Posted on 2024-02-15

2419 Cross-species single-cell annotation with orthologous marker gene groups

Chau, T.; Timilsena, P. R.; Kundu, S.; Bathala, S. P.; Bargmann, B.; Li, S.

10.1101/2023.06.18.545471 — bioinformatics — Posted on 2024-02-15

2420 Measuring, visualizing and diagnosing reference bias with biastools

Lin, M.-J.; Iyer, S.; Chen, N.-C.; Langmead, B.

10.1101/2023.09.13.557552 — bioinformatics — Posted on 2024-02-15

2421 Non-targeted isomer-sensitive N-glycome analysis reveals new layers of organ-specific diversity in mice.

Helm, J.; Mereiter, S.; Oliveira, T.; Gattinger, A.; Markovitz, D. M.; Penninger, J. M.; Altmann, F.; Stadlmann, J.

10.1101/2022.09.19.508483 — biochemistry — Posted on 2024-02-15

2422 Working memory constraints for visuomotor retrieval strategies

Vargas, C. A. V.; Taylor, J. A.

10.1101/2024.02.13.580155 — animal behavior and cognition — Posted on 2024-02-15

2423 Experimental evolution for the recovery of growth loss due to genome reduction

Hitomi, K.; Ishii, Y.; Ying, B.-W.

10.1101/2023.11.08.566234 — evolutionary biology — Posted on 2024-02-15

2424 Spatial conservation planning of forest genetic resources in a Mediterranean multi-refugial area

Vajana, E.; Andrello, M.; Avanzi, C.; Bagnoli, F.; Vendramin, G. G.; Piotti, A.

10.1101/2023.11.06.565750 — evolutionary biology — Posted on 2024-02-15

2425 Unraveling the Genomic Diversity and Admixture History of Captive Tigers in the United States

Armstrong, E. E.; Mooney, J. A.; Solari, K. A.; Kim, B. Y.; Barsh, G. S.; Grant, V. B.; Greenbaum, G.; Kaelin, C. B.; Panchenko, K.; Pickrell, J. K.; Rosenberg, N.; Ryder, O. A.; Yokoyama, T.; Ramakrishnan, U.; Petrov, D. A.; Hadly, E. A.

10.1101/2023.06.19.545608 — evolutionary biology — Posted on 2024-02-15

2426 Using artificial intelligence to document the hidden RNA virosphere

Hou, X.; He, Y.; Fang, P.; Mei, S.-Q.; Xu, Z.; Wu, W.-C.; Tian, J.-H.; Zhang, S.; Zeng, Z.-Y.; Gou, Q.-Y.; Xin, G.-Y.; Le, S.-J.; Xia, Y.-Y.; Zhou, Y.-L.; Hui, F.-M.; Pan, Y.-F.; Eden, J.-S.; Yang, Z.-H.; Han, C.; Shu, Y.-L.; Guo, D.; Li, J.; Holmes, E. C.; Li, Z.-R.; Shi, M.

10.1101/2023.04.18.537342 — microbiology — Posted on 2024-02-15

2427 Molecular mechanisms underlying the modulation of T-cell proliferation and cytotoxicity by immobilized CCL21 and ICAM1

Yado, S.; Dassa, B.; Zoabi, R.; Reich-Zeliger, S.; Friedman, N.; Geiger, B.

10.1101/2024.02.07.578152 — immunology — Posted on 2024-02-15

2428 Neural dynamics of shifting attention between perception and working-memory contents

Gresch, D.; Boettcher, S. E. P.; van Ede, F.; Nobre, A. C.

10.1101/2024.02.14.580280 — neuroscience — Posted on 2024-02-15

2429 Rate of brain aging associates with future executive function in Asian children and older adults

Cheng, S. F.; Yue, W. L.; Ng, K. K.; Qian, X.; Liu, S.; Tan, T. W. K.; Nguyen, K.-N.; Leong, R. L. F.; Hilal, S.; Cheng, C.-Y.; Tan, A. P.; Law, E. C.; Gluckman, P. D.; Chen, C. L.-H.; Chong, Y. S.; Meaney, M. J.; Chee, M.; Yeo, B. T. T.; Zhou, J. H.

10.1101/2023.11.27.568184 — neuroscience — Posted on 2024-02-15

2430 A simple optical flow model explains why certain object viewpoints are special

Stewart, E. E. M.; Fleming, R. W.; Schuetz, A. C.

10.1101/2023.10.02.560466 — neuroscience — Posted on 2024-02-15

2431 Emergence of Supercoiling-Mediated Regulatory Networks through Bacterial Chromosome Organization

Grohens, T.; Meyer, S.; Beslon, G.

10.1101/2022.09.23.509185 — systems biology — Posted on 2024-02-15

2432 Charm is a flexible pipeline to simulate chromosomal rearrangements on Hi-C-like data.

Nuriddinov, M.; Belokopytova, P.; Fishman, V.

10.1101/2023.11.22.568374 — bioinformatics — Posted on 2024-02-15

2433 Points2Regions: Fast, interactive clustering of imaging-based spatial transcriptomics data

Andersson, A.; Behanova, A.; Windhager, J.; Avenel, C.; Malmberg, F.; Wählby, C.

10.1101/2022.12.07.519086 — bioinformatics — Posted on 2024-02-15

2434 A unified hypothesis-free feature extraction framework for diverse epigenomic data

Balci, A. T.; Chikina, M.

10.1101/2023.01.26.525794 — bioinformatics — Posted on 2024-02-15

2435 Orientation-Independent-DIC imaging reveals that a transient rise in depletion force contributes to mitotic chromosome condensation

Iida, S.; Ide, S.; Tamura, S.; Tani, T.; Goto, T.; Shribak, M.; Maeshima, K.

10.1101/2023.11.11.566679 — cell biology — Posted on 2024-02-15

2436 Hippocampal area CA2 activity supports social investigation following an acute social stress.

Radzicki, D.; E. McCann, K. E.; Alexander, G. M.; Dudek, S. M.

10.1101/2024.02.14.580182 — neuroscience — Posted on 2024-02-15

2437 Metaplastic tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer

Salas-Escabillas, D. J.; Hoffman, M. T.; Moore, J. S.; Brender, S. M.; Wen, H.-J.; Benitz, S.; Davis, E. T.; Long, D.; Wombwell, A. M.; Steele, N. G.; Sears, R. C.; Matsumoto, I.; DelGiorno, K. E.; Crawford, H. C.

10.1101/2024.02.12.579982 — cancer biology — Posted on 2024-02-14

2438 Covering the bases: population genomic structure of Lemna minor and the cryptic species L. japonica in Switzerland

Schmid, M. W.; Moradi, A.; Leigh, D. M.; Schuman, M. C.; van Moorsel, S. J.

10.1101/2024.02.14.580260 — genomics — Posted on 2024-02-14

2439 Knockdown Resistance (kdr) Associated Organochlorine Resistance in Mosquito-Borne Diseases (Culex quinquefasciatus): Systematic Study of Reviews and Meta-Analysis

ABBASI, E.; Daliri, S.

10.1101/2024.02.13.580052 — zoology — Posted on 2024-02-14

2440 Maramycin, a cytotoxic isoquinolinequinone terpenoid produced through heterologous expression of a bifunctional indole prenyltransferase /tryptophan indole-lyase in S. albidoflavus

Maleckis, M.; Wibowo, M.; Williams, S. E.; Gotfredsen, C. H.; Sigrist, R.; Souza, L. D. O.; Cowled, M. S.; Charusanti, P.; Gren, T.; Saha, S.; Moreira, J. M. A.; Weber, T.; Ding, L.

10.1101/2024.02.14.580309 — bioengineering — Posted on 2024-02-14

2441 Resilience and Charge-Dependent Fibrillation of Functional Amyloids: Interactions of Pseudomonas Biofilm-Associated FapB and FapC

Golan, N.; Parizat, A.; Tabachnikov, O.; Barnea, E.; Olsen, W. P.; Otzen, D. E.; Landau, M.

10.1101/2024.02.14.580233 — biochemistry — Posted on 2024-02-14

2442 Surveying the landscape of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data

Page, M. L.; Aguzzoli Heberle, B.; Brandon, J. A.; Wadsworth, M.; Gordon, L. A.; Nations, K. A.; Ebbert, M. T. W.

10.1101/2024.02.13.579945 — genomics — Posted on 2024-02-14

2443 Uncovering the simple adhesive strategy of the Toxoplasma parasite for high-speed motility

Vigetti, L.; Touquet, B.; Debarre, D.; Rose, T.; Bureau, L.; Abdallah, D.; Dubacheva, G.; Tardieux, I.

10.1101/2024.02.13.580110 — cell biology — Posted on 2024-02-14

2444 Central Role for Glycolysis and Fatty Acids in LH-responsive Progesterone Synthesis

Przygrodzka, E.; Binderwala, F.; Powers, R.; McFee, R. M.; Cupp, A. S.; Wood, J. R.; Davis, J. S.

10.1101/2024.02.14.580329 — molecular biology — Posted on 2024-02-14

2445 Translational response to mitochondrial stresses is orchestrated by tRNA modifications.

Rashad, S.; Al-Mesitef, S.; Mousa, A.; Zhou, Y.; Ando, D.; Sun, G.; Fukuuchi, T.; Iwasaki, Y.; Xiang, J.; Byrne, S. R.; Sun, J.; Maekawa, M.; Saigusa, D.; Begley, T.; Dedon, P.; Niizuma, K.

10.1101/2024.02.14.580389 — molecular biology — Posted on 2024-02-14

2446 A single amino acid in the Salmonella effector SarA/SteE triggers supraphysiological activation of STAT3 for anti-inflammatory target gene expression

Gaggioli, M. R.; Jones, A. G.; Panagi, I.; Washington, E. J.; Loney, R. E.; Muench, J. H.; Brennan, R. G.; Thurston, T. L. M.; Ko, D. C.

10.1101/2024.02.14.580367 — molecular biology — Posted on 2024-02-14

2447 Protein UFMylation regulates early events of ribosomal DNA double-stranded break response

Panichnantakul, P.; Aguilar, L. C.; Daynard, E.; Guest, M.; Peters, C.; Vogel, J.; Oeffinger, M.

10.1101/2024.02.14.580383 — molecular biology — Posted on 2024-02-14

2448 Angiogenin regulates mitochondrial stress and function via tRNA-derived fragments generation and impacting tRNA modifications.

Al-Mesitef, S.; Tominaga, K.; Mousa, A.; Begley, T.; Dedon, P.; Rashad, S.; Niizuma, K.

10.1101/2024.02.13.580206 — molecular biology — Posted on 2024-02-14

2449 Shifting to biology promotes highly efficient iron removal in groundwater filters

Mueller, S.; Corbera-Rubio, F.; Schoonenberg-Kegel, F.; Laureni, M.; van Loosdrecht, M.; van Halem, D.

10.1101/2024.02.14.580244 — microbiology — Posted on 2024-02-14

2450 The Northern Colours: Isolation and Characterisation of 4 Pigment-Producing Bacteria from the Arctic

Das, J.; Singh, A. K.

10.1101/2024.02.13.579883 — microbiology — Posted on 2024-02-14

2451 Paired metagenomic and chemical evaluation of an aflatoxin contaminated dog kibble

Ottesen, A.; Kocurek, B. J.; Reed, E.; Commichaux, S.; Mammel, M. K.; Ramachandran, P.; McDermott, P. F.; Flannery, B. M.; Strain, E. A.

10.1101/2024.02.14.580305 — microbiology — Posted on 2024-02-14

2452 RelQ-mediated alarmone signaling regulates growth, sporulation, and stress-induced biofilm formation in Clostridioides difficile

Malik, A.; Oludiran, A.; Poudel, A.; Alvarez, O. B.; Woodward, C.; Purcell, E. B.

10.1101/2024.02.14.580318 — microbiology — Posted on 2024-02-14

2453 Development of a signal-integrating reporter to monitor mitochondria-ER contacts

Yang, Z.; Chan, D.

10.1101/2024.02.14.580376 — synthetic biology — Posted on 2024-02-14

2454 SbPIP2 Mediated Improvements in Plant Resilience: Physiological and Molecular Insights into Abiotic Stress Response

Patel, J.; Khatri, K.; Gupta, N. K.; Maniar, J.; Khandwal, D.; Choudhary, B.; Phillips, D.; Jones, H. D.; Mishra, A.

10.1101/2024.02.13.580036 — plant biology — Posted on 2024-02-14

2455 HairSplitter: haplotype assembly from long, noisy reads

Faure, R.; Lavenier, D.; Flot, J.-F.

10.1101/2024.02.13.580067 — bioinformatics — Posted on 2024-02-14

2456 Single-cell Masked Autoencoder: An Accurate and Interpretable Automated Immunophenotyper

10.1101/2024.02.13.580114 — bioinformatics — Posted on 2024-02-14

2457 Virus-free CRISPR knock-in of a chimeric antigen receptor into KLRC1 generates potent GD2-specific natural killer cells

Shankar, K.; Zingler-Hoslet, I.; Shi, L.; Katta, V.; Russell, B. E.; Tsai, S. Q.; Capitini, C. M.; Saha, K.

10.1101/2024.02.14.580371 — bioengineering — Posted on 2024-02-14

2458 Mapping protein-metabolite interactions in E. coli by integrating chromatographic techniques and co-fractionation mass spectrometry.

Wagner, M. M.; Kang, J.; Mercado, C.; Thirumlaikumar, V. P.; Gorka, M.; Zillmer, H.; Guo, J.; Minen, R. I.; Plecki, C. F.; Dehesh, K.; Schroeder, F. C.; Walther, D.; Skirycz, A.

10.1101/2024.02.14.580258 — biochemistry — Posted on 2024-02-14

2459 Development of subunit selective proteasome substrates for Schistosoma species

Jiang, Z.; Da Silva, E. B.; Liu, C.; Fajtova, P.; Liu, L. J.; El-Sakkary, N.; Skinner, D.; Syed, A.; Wang, S. C.; Caffrey, C. J.; O'Donoghue, A. J.

10.1101/2024.02.13.580161 — biochemistry — Posted on 2024-02-14

2460 Structural basis of Cdk7 activation by dual T-loop phosphorylation

Duster, R.; Anand, K.; Binder, S. C.; Schmitz, M.; Gatterdam, K.; Fisher, R. P.; Geyer, M.

10.1101/2024.02.14.580246 — biochemistry — Posted on 2024-02-14

2461 Unique growth and morphology properties of Clade 5 Clostridioides difficile strains revealed by single-cell time-lapse microscopy

Ribis, J. W.; Nieto-Acuna, C. A.; Dong, Q.; DiBenedetto, N.; Mehra, A.; Nagawa, I. L.; El Meouche, I.; Aldridge, B. B.; Dunlop, M. J.; Tamayo, R.; Singh, A.; Shen, A.

10.1101/2024.02.13.580212 — microbiology — Posted on 2024-02-14

2462 Inhibition of epithelial Na+ transport: novel mechanism of Ureaplasma-driven lung disease

Glaser, K.; Rieger, C.-B.; Paluszkiewicz, E.; Thome, U. H.; Laube, M.

10.1101/2024.02.14.580256 — microbiology — Posted on 2024-02-14

2463 Complex carbohydrate utilization by gut bacteria modulates host food preference

Yu, K. B.; Son, C.; Chandra, A.; Paramo, J.; Novoselov, A.; Ozcan, E.; Kazmi, S.; Lum, G.; Lopez-Romero, A.; Lynch, J.; Hsiao, E. Y.

10.1101/2024.02.13.580152 — microbiology — Posted on 2024-02-14

2464 Distribution of soil and clinical Burkholderia pseudomallei isolates in Myanmar by using MLST

Aung, N. M.; Htut, K. M.; Aung, H. T.; Than, A. M.; Oo, K. Z.; Su, K. K.

10.1101/2024.02.14.580235 — microbiology — Posted on 2024-02-14

2465 Anti-capsule human monoclonal antibodies protect against hypervirulent and pandrug-resistant Klebsiella pneumoniae

10.1101/2024.02.14.580141 — microbiology — Posted on 2024-02-14

2466 Hosts Manipulate Lifestyle Switch and Pathogenicity Heterogeneity of Opportunistic Pathogens in the Single-cell Resolution

Wang, Z.; Li, S.; Zhang, S.; Zhang, T.; Wu, Y.; Liu, A.; Wang, K.; Ji, X.; Cao, H.; Tan, E. K.; Wang, Y.; Wang, Y.; Liu, W.

10.1101/2024.02.14.580325 — microbiology — Posted on 2024-02-14

2467 Loss of function of metabolic traits in typhoidal Salmonella without apparent genome degradation

Machado, L. F. M.; Galan, J. E.

10.1101/2024.02.14.580360 — microbiology — Posted on 2024-02-14

2468 The atypical antipsychotic aripiprazole alters the outcome of disseminated Candida albicans infections.

Reitler, P.; Regan, J.; DeJarnette, C.; Srivastava, A.; Carnahan, J. A.; Tucker, K. M.; Meibohm, B.; Peters, B. M.; Palmer, G. E.

10.1101/2024.02.13.580133 — microbiology — Posted on 2024-02-14

2469 Pooled PPIseq: screening the SARS-CoV-2 and human interface with a scalable multiplexed protein-protein interaction assay platform

Miller, D.; Dziulko, A.; Levy, S.

10.1101/2024.02.13.580123 — systems biology — Posted on 2024-02-14

2470 Epigenome and early selection determine the tumour-immune evolutionary trajectory of colorectal cancer

Lakatos, E.; Gunasri, V.; Zapata, L.; Househam, J.; Heide, T.; Trahearn, N.; Swinyard, O.; Cisneros, L.; Lynn, C.; Mossner, M.; Kimberley, C.; Spiteri, I.; Cresswell, G. D.; Llibre-Palomar, G.; Mitchison, M.; Maley, C. C.; Jansen, M.; Rodriguez-Justo, M.; Bridgewater, J.; Baker, A.-M.; Sottoriva, A.; Graham, T. A.

10.1101/2024.02.12.579956 — cancer biology — Posted on 2024-02-14

2471 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-02-14

2472 A Curated Cell Life Imaging Dataset of Immune-enriched Pancreatic Cancer Organoids with Pre-trained AI Models

Kulkarni, A.; Ferreira, N.; Scodellaro, R.; Alves, F.

10.1101/2024.02.12.580032 — cancer biology — Posted on 2024-02-14

2473 Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor DR2539

Mota, C.; Webster, M.; Saidi, M.; Kapp, U.; Zubieta, C.; Giachin, G.; Manso, J. A.; de Sanctis, D.

10.1101/2024.02.12.579695 — biophysics — Posted on 2024-02-14

2474 Conformational landscapes of Huntingtin's polyQ domain and variations in its aggregate morphology

Nanajkar, N.; Sahoo, A.; Matysiak, S.

10.1101/2024.02.12.579983 — biophysics — Posted on 2024-02-14

2475 Development of a novel in silico classification model to assess reactive metabolite formation in the cysteine trapping assay and investigation of important substructures

Umemori, Y.; Handa, K.; Yoshimura, S.; Kageyama, M.; Iijima, T.

10.1101/2024.02.12.580017 — bioinformatics — Posted on 2024-02-14

2476 Mapping Cell Fate Transition in Space and Time

Liu, J.; Gu, Y.; Li, C.; Welch, J. D.

10.1101/2024.02.12.579941 — bioinformatics — Posted on 2024-02-14

2477 DEEP LEARNING APPROACH FOR RENAL CELL CARCINOMA DETECTION,SUBTYPING, AND GRADING

Aziz, M. A.; Javadian, F.; Susheel, S.; Gopal, A.; Stegmaier, J.; Jose, A.

10.1101/2024.02.12.577550 — bioinformatics — Posted on 2024-02-14

2478 Data mining antibody sequences for database searching in bottom-up proteomics

Trinh, X.-T.; Freitag, R.; Krawczyk, K.; Schwammle, V.

10.1101/2024.02.13.580076 — bioinformatics — Posted on 2024-02-14

2479 Memory-bound k-mer selection for large evolutionary diverse reference libraries

Sapci, A. O. B.; Mirarab, S.

10.1101/2024.02.12.580015 — bioinformatics — Posted on 2024-02-14

2480 Common data models to streamline metabolomics processing and annotation, and implementation in a Python pipeline

Mitchell, J.; Chi, Y.; Thapa, M.; Pang, Z.; Xia, J.; Li, S.

10.1101/2024.02.13.580048 — bioinformatics — Posted on 2024-02-14

2481 Cell-free expression and biochemical characterization of polysaccharide-synthesizing glycosyltransferases

Jayachandran, D.; Parvate, A.; Brookreson, J. T.; Evans, J. E.; Chundawat, S. P. S.

10.1101/2024.02.12.580006 — bioengineering — Posted on 2024-02-14

2482 Predictive simulation of human movement in OpenSim using floating-base task space control

Pickle, N. T.; Sundararajan, A.

10.1101/2024.02.13.580044 — bioengineering — Posted on 2024-02-14

2483 The interplay of trophic interactions and game dynamics gives rise to life-history trade-offs, consistent personalities, and predator-prey and aggression power laws

Salahshour, M.

10.1101/2024.02.13.580043 — ecology — Posted on 2024-02-14

2484 Accelerating joint species distribution modeling with Hmsc-HPC: A 1000x faster GPU deployment

Rahman, A. U.; Tikhonov, G.; Oksanen, J.; Rossi, T.; Ovaskainen, O.

10.1101/2024.02.13.580046 — ecology — Posted on 2024-02-14

2485 Oncogenic KRAS cells use Wnt signalling and cell dormancy to override homeostatic cell elimination mechanisms in adult pancreas.

Salvador-Barbero, B.; Alatsatianos, M.; Morton, J. P.; Sansom, O. J.; Hogan, C.

10.1101/2024.02.13.579930 — cell biology — Posted on 2024-02-14

2486 mTOR signaling regulates aberrant epithelial cell proliferative and migratory behaviors characteristic of airway mucous metaplasia in asthma

Kudrna, K.; Staab, E. B.; Eilers, E.; Thomes, P.; Maurya, S.; Brody, S. L.; Wyatt, T. A.; Bailey, K. L.; Dickinson, J. D.

10.1101/2024.02.12.579905 — cell biology — Posted on 2024-02-14

2487 Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire

Altman, P.; Ozorowski, G.; Stanfield, R.; Haakenson, J.; Appel, M.; Parren, M.; Lee, W.-H.; Sang, H.; Woehl, J.; Saye-Francisco, K.; Joyce, C.; Song, G.; Porter, K.; Landais, E.; Andrabi, R.; Wilson, I.; Ward, A.; Mwangi, W.; Smider, V.; Burton, D.; Sok, D.

10.1101/2024.02.13.580058 — immunology — Posted on 2024-02-14

2488 A spring-loaded and leakage-tolerant synthetic gene switch for in-vitro detection of DNA and RNA

Gupta, K.; Krieg, E.

10.1101/2024.02.12.579921 — synthetic biology — Posted on 2024-02-14

2489 A Workflow for Improved Analysis of Cross-linking Mass Spectrometry Data Integrating Parallel Accumulation-Serial Fragmentation with MeroX and Skyline

Rojas Echeverri, J. C.; Hause, F.; Iacobucci, C.; Ihling, C. H.; Tanzler, D.; Shulman, N.; Riffle, M.; MacLean, B.; Sinz, A.

10.1101/2024.02.13.580038 — bioinformatics — Posted on 2024-02-14

2490 Targeted genotyping-by-sequencing of potato and software for imputation

Endelman, J. B.; Kante, M.; Lindqvist-Kreuze, H.; Kilian, A.; Shannon, L. M.; Caraza-Harter, M. V.; Vaillancourt, B.; Mailloux, K.; Hamilton, J. P.; Buell, C. R.

10.1101/2024.02.12.579978 — genomics — Posted on 2024-02-14

2491 Quantitative genetics of natural S. cerevisiae strains upon sexual mating reveals heritable determinants of cellular fitness

Struass, S. K.; Golomb, R.; Sheykhkarimli, D.; Liti, G.; Dahan, O.; Pilpel, Y. T.

10.1101/2024.02.12.579867 — genetics — Posted on 2024-02-14

2492 Pathogen and pest risks to vegetatively propagated crops in humanitarian contexts: Geographic priorities for Cameroon and Ethiopia

Mouafo-Tchinda, R.; Etherton, B.; Plex Sula, A.; Andrade-Piedra, J.; Ogero, K.; Omondi, B. A.; McEwan, M.; Tene Tayo, P.; Harahagazwe, D.; Cherinet, M.; Gebeyehu, S.; Sperling, L.; Garrett, K. A.

10.1101/2024.02.12.580019 — ecology — Posted on 2024-02-14

2493 Emergence and spread of SARS-CoV-2 variants from farmed mink to humans and back during the epidemic in Denmark, June-November 2020.

10.1101/2024.02.13.580053 — microbiology — Posted on 2024-02-14

2494 Evaluation of a novel Tc-24 recombinant antigen ELISA for serologic testing for Trypanosoma cruzi in dogs

Mejia, R.; Verocai, G. G.; Mosley, I. A.; Zhan, B.; Vongthavaravat, L.; Busselman, R. E.; Hamer, S. A.

10.1101/2024.02.12.579969 — zoology — Posted on 2024-02-14

2495 Postdoctoral Scholar Recruitment and Hiring Practices in STEM: A Pilot Study

Heirwegh, M.; Rees, D. C.; Malcom-Piqueux, L.

10.1101/2024.02.12.580018 — scientific communication and education — Posted on 2024-02-14

2496 Discovery of a new Myristica swamp in the Northern Western Ghats of India.

Desai, P. D.; Sadekar, V. G.; Desai, S. P.

10.1101/2024.02.12.579903 — plant biology — Posted on 2024-02-14

2497 ROS responsive Aux/IAA multimerization modulates auxin responses

Roy, D.; Mehra, P.; Mukkawar, V.; Clark, L.; Bellande, K.; Vermeer, J. E.; Arevallilo, R. M.; VERNOUX, T.; Sue ob, K.; Jones, A. R.; Bechtold, U.; Mullineaux, P. M.; Lilley, K.; Brown, A.; Bennett, M.; Sadanandom, A.

10.1101/2024.02.12.579961 — plant biology — Posted on 2024-02-14

2498 Ultraviolet attenuates centromere-mediated meiotic genome stability and alters gametophytic ploidy consistency in flowering plants

Fu, H.; Zhong, J.; Zhao, J.; Huo, L.; Wang, C.; Ma, D.; Pan, W.; Sun, L.; Ren, Z.-M.; Fan, T.; Wang, Z.; Wang, W.; Lei, X.; Yu, G.; Li, J.; Zhu, Y.; Geelen, D. N. V.; Liu, B.

10.1101/2024.02.12.579936 — plant biology — Posted on 2024-02-14

2499 Functional characterization of two glycosyltransferases from Withania somnifera illuminates their role in withanosides biosynthesis and defence against bacteria

Anjali, P.; Narayanan, A. K.; Parihar, D.; Patil, A.; Nagegowda, D. A.

10.1101/2024.02.12.579880 — plant biology — Posted on 2024-02-14

2500 Proteolytic Cleavage of the ENaC gamma Subunit: Impact Upon Na+ and K+ Handling

Ray, E. C.; Nickerson, A.; Sheng, S.; Carrisoza-Gaytan, R.; Lam, T.; Marciszyn, A.; Zhang, L.; Jordahl, A.; Bi, C.; Winfrey, A.; Kou, Z.; Gingras, S.; Kirabo, A.; Satlin, L. M.; Kleyman, T. R.

10.1101/2024.02.12.579964 — physiology — Posted on 2024-02-14

2501 Bisphenol A induces sex-dependent alterations in the dynamics of neuroendocrine seasonal adaptation in Djungarian hamsters

SIMONNEAUX, V.; MORALIA, M.-A.; BOTHOREL, B.; ANDRY, V.

10.1101/2024.02.12.580037 — physiology — Posted on 2024-02-14

2502 Matching dynamically varying forces with multi-motor-unit muscle models: A simulation study

Murtola, T.; Richards, C.

10.1101/2024.02.13.580042 — physiology — Posted on 2024-02-14

2503 A Specialized Centrosome-Proteasome Axis Mediates Proteostasis and Influences Cardiac Stress through Txlnb

McLendon, J. M.; Zhang, X.; Stein, C. C.; Baehr, L. M.; Bodine, S. C.; Boudreau, R. L.

10.1101/2024.02.12.580020 — physiology — Posted on 2024-02-14

2504 Hyperactivity Induced By Vapor Inhalation of Nicotine in Male and Female Rats

Javadi-Paydar, M.; Kerr, T. M.; Taffe, M. A.

10.1101/2024.02.12.579996 — pharmacology and toxicology — Posted on 2024-02-14

2505 Named Entity Recognition of Pharmacokinetic parameters in the scientific literature

Hernandez, F. G.; Nguyen, Q.; Smith, V. C.; Cordero, J. A.; Ballester, M. R.; Duran, M.; Sole, A.; Chotsiri, P.; Wattanakul, T.; Mundin, G.; Lilaonitkul, W.; Standing, J. F.; Kloprogge, F.

10.1101/2024.02.12.580001 — pharmacology and toxicology — Posted on 2024-02-14

2506 Tumor-localized interleukin-2 and interleukin-12 combine with radiation therapy to safely potentiate regression of advanced malignant melanoma in pet dogs

Stinson, J. A.; Barbosa, M. M. P.; Sheen, A.; Momin, N.; Fink, E.; Hampel, J.; Selting, K.; Kamerer, R.; Bailey, K. L.; Wittrup, K. D.; Fan, T. M.

10.1101/2024.02.12.579965 — cancer biology — Posted on 2024-02-14

2507 Developing machine-learning-based amyloid predictors with Cross-Beta DB

Gonay, V.; Dunne, M. P.; Caceres-Delpiano, J.; Kajava, A. V.

10.1101/2024.02.12.579644 — bioinformatics — Posted on 2024-02-14

2508 Discovering genotype-phenotype relationships with machine learning and the Visual Physiology Opsin Database (VPOD)

Frazer, S. A.; Baghbanzadeh, M.; Rahnavard, A.; Crandall, K. A.; Oakley, T. H.

10.1101/2024.02.12.579993 — bioinformatics — Posted on 2024-02-14

2509 Deciphering Peptide-Protein Interactions via Composition-Based Prediction: A Case Study with Survivin/BIRC5

Anindya, A. L.; Olsson, T. N.; Jensen, M.; Garcia-Bonete, M.-J.; Wheatley, S.; Bokarewa, M.; Mezzasalma, S. A.; Katona, G.

10.1101/2024.02.12.579763 — bioinformatics — Posted on 2024-02-14

2510 Developing and Investigating a Nanovibration Intervention for the Prevention/Reversal of Bone Loss Following Spinal Cord Injury

Williams, J. A.; Campsie, P.; Gibson, R.; Johnson-Love, O.; Werber, A. S.; Sprott, M.; Meechan, R.; Huesa, C.; Windmill, J. F. C.; Purcell, M.; Coupaud, S.; Dalby, M. J.; Childs, P. G.; Riddell, J. S.; Reid, S.

10.1101/2024.02.12.578222 — bioengineering — Posted on 2024-02-14

2511 A reference genome for the Chinese Lizardtail Herb (Saururus chinensis)

Tang, C.

10.1101/2024.02.12.579984 — genomics — Posted on 2024-02-14

2512 Controlling for polygenic genetic confounding in epidemiologic association studies

Zhao, Z.; Yang, X.; Miao, J.; Dorn, S.; Barcellos, S.; Fletcher, J.; Lu, Q.

10.1101/2024.02.12.579913 — genetics — Posted on 2024-02-14

2513 Translating Ethiopian potato seed networks: Identifying strategic intervention points for managing bacterial wilt and other diseases

Etherton, B.; Plex Sula, A.; Mouafo-Tchinda, R.; Kakuhenzire, R.; Kassaye, H.; Asfaw, F.; Kosmakos, V.; McCoy, R.; Xing, Y.; Yao, J.; Sharma, K.; Garrett, K. A.

10.1101/2024.02.12.579952 — ecology — Posted on 2024-02-14

2514 Quantitative analysis of MHC class II peptide exchange reveals pivotal role of peptide association rate

Günther, M.; Sticht, J.; Freund, C.; Höfer, T.

10.1101/2024.02.12.579932 — systems biology — Posted on 2024-02-14

2515 Relationship between advanced footwear technology longitudinal bending stiffness and energy cost of running

Rodrigo, V.; Hoogkamer, W.; Gonzalez-Rave, J. M.; Gonzalez-Mohino, F.

10.1101/2023.12.27.573423 — physiology — Posted on 2024-02-14

2516 Reliability of transcranial magnetic stimulation-evoked responses on knee extensor muscles during cycling

Zhang, J.; McClean, Z. J.; Khaledi, N.; Morgan, S.-J.; Millet, G. Y.; Aboodarda, S. J.

10.1101/2024.02.12.579935 — physiology — Posted on 2024-02-14

2517 Mastication while rested does not improve sustained attention in healthy participants conducting short-duration cognitive tasks

Hansen, D.; Maislin, G.; Day, J.

10.1101/2024.02.12.579989 — physiology — Posted on 2024-02-14

2518 Skin Sensitisation Case Study: Comparison of Defined Approaches including OECD 497 Guidance

Hardy, B.; Ankli, P.; Parween, S.; Lopez, B.; Daligaux, P.; Mohoric, T.; Darde, T.; Chesne, C.; Stockman, N.; Boglari, C.; Poon, A.

10.1101/2024.02.12.579980 — pharmacology and toxicology — Posted on 2024-02-14

2519 DexDesign: A new OSPREY-based algorithm for designing de novo D-peptide inhibitors

Guerin, N.; Childs, H.; Zhou, P.; Donald, B. R.

10.1101/2024.02.12.579944 — bioinformatics — Posted on 2024-02-14

2520 NEKL-4 regulates microtubule stability and mitochondrial health in C. elegans ciliated neurons

Power, K. M.; Nguyen, K. C.; Silva, A.; Singh, S.; Hall, D. H.; Rongo, C.; Barr, M. M.

10.1101/2024.02.14.580304 — cell biology — Posted on 2024-02-14

2521 Caspase-2 kills cells with extra centrosomes

Rizzotto, D.; Vigorito, V.; Rieder, P.; Gallob, F.; Moretta, G. M.; Soratroi, C.; Riley, J.; Bellutti, F.; Li Veli, S.; Mattivi, A.; Lohmueller, M.; Herzog, S.; Bornhauser, B. C.; Jacotot, E. D.; Villunger, A.; Fava, L. L.

10.1101/2024.02.13.580097 — cell biology — Posted on 2024-02-14

2522 Mechanism Study on the Effect of Kidney Tonifying and Liver Soothing Methods on Mouse Oocyte Quality by Regulating OSFs and Smads Pathways

Zhang, R.; Jia, R.; Bai, J.; Du, H.; Yang, L.

10.1101/2024.02.12.579988 — synthetic biology — Posted on 2024-02-14

2523 The effect of constitutive root isoprene emission on root phenotype and physiology under control and salt stress conditions

Bellucci, M.; Mostofa, M. G.; Weraduwage, S. M.; Xu, Y.; Abdelrahman, M.; De Gara, L.; Loreto, F.; Sharkey, T. D.

10.1101/2024.02.09.579703 — plant biology — Posted on 2024-02-14

2524 Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis

Vastrad, B. M.; Vastrad, C. M.

10.1101/2024.02.10.579759 — bioinformatics — Posted on 2024-02-14

2525 Working memory constraints for visuomotor retrieval strategies

Vargas, C. A. V.; Taylor, J. A.

10.1101/2024.02.13.580155 — animal behavior and cognition — Posted on 2024-02-14

2526 Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage

Shukla, N.; Roelle, S. M.; Snell, J. C.; DelSignore, O.; Bruchez, A. M.; Matreyek, K. A.

10.1101/2024.02.13.580056 — genetics — Posted on 2024-02-14

2527 Developmental emergence of quiescent-like neural progenitor cells in the zebrafish embryonic brain

Liu, Y.; Lembke, C.-S.; Paridaen, J. T. M. L.

10.1101/2024.02.13.580083 — developmental biology — Posted on 2024-02-14

2528 NOTUM-MEDIATED WNT SILENCING DRIVES EXTRAVILLOUS TROPHOBLAST CELL LINEAGE DEVELOPMENT

Shukla, V.; Irusta, A. M.; Varberg, K. M.; Kuna, M.; Iqbal, K.; Galligos, A. M.; Aplin, J. D.; Choudhury, R. H.; Okae, H.; Arima, T.; Soares, M. J.

10.1101/2024.02.13.579974 — developmental biology — Posted on 2024-02-14

2529 Signatures of structural disorder in developing epithelial tissues

Cupo, C.; Allan, C.; Ailiani, V.; Kasza, K. E.

10.1101/2024.02.12.579900 — developmental biology — Posted on 2024-02-14

2530 Trim66 paternal deficiency causes intrauterine overgrowth

Mielnicka, M.; Tabaro, F.; Sureka, R.; Acurzio, B.; Paoletti, R.; Scavizzi, F.; Raspa, M.; Crevenna, A. H.; Lapouge, K.; Remans, K.; Boulard, M.

10.1101/2024.02.12.579976 — developmental biology — Posted on 2024-02-14

2531 The Drosophila histone methyl-transferase SET1 coordinates multiple signaling pathways in regulating male germline stem cell maintenance and differentiation

Vidaurre, V.; Song, A.; Li, T.; Ku, W. L.; Zhao, K.; Qian, J.; Chen, X.

10.1101/2024.02.14.580277 — developmental biology — Posted on 2024-02-14

2532 Lineage-specific intersection of endothelin and GDNF signaling in enteric nervous system development

Poltavski, D. M.; Cunha, A. T.; Tan, J. V. S.; Sucov, H. M.; Makita, T.

10.1101/2024.02.13.580135 — developmental biology — Posted on 2024-02-14

2533 A new paradigm considering multicellular adhesion, repulsion and attraction represent diverse cellular tile patterns

Carrillo, J. A.; Murakawa, H.; Sato, M.; Wang, M.

10.1101/2024.02.13.580045 — developmental biology — Posted on 2024-02-14

2534 Early mechanisms of aortic failure in a zebrafish model for thoracic aortic dissection and rupture

10.1101/2024.02.12.580022 — developmental biology — Posted on 2024-02-14

2535 Mitigation of Fetal Irradiation Injury from Mid-Gestation Total Body Radiation with Mitochondrial-Targeted GS-Nitroxide JP4-039

Wu, Y. L.; Ghristodoulou, A. G.; Beumer, J. H.; Rigatti, L. H.; Fisher, R.; Ross, M.; Watkins, S.; Cortes, D. R. E.; Ruck, C.; Manzoor, S.; Wyman, S. K.; Stapleton, M. C.; Goetzman, E.; Bharathi, S.; Wipf, P.; Tan, T.; Eiseman, J. L.; Christner, S. M.; Guo, J.; Lo, C. W. Y.; Epperly, M. W.; Greenberger, J. S.

10.1101/2024.02.13.580105 — developmental biology — Posted on 2024-02-14

2536 Duplication of the anteroposterior body axis in postembryos of the Eratigena atrica spider

Napiorkowska, T.; Templin, J.; Napiorkowski, P.

10.1101/2024.02.14.580276 — developmental biology — Posted on 2024-02-14

2537 Localization and function of key axonemal microtubule inner proteins and dynein docking complex members reveal extensive diversity among vertebrate motile cilia

Roy, S.; LU, H.; Twan, W. K.; Ikawa, Y.; Khare, V. P.; Mukherjee, I.; Chua, K. X.; Chakrabarti, S.; Hamada, H.

10.1101/2024.02.14.580281 — developmental biology — Posted on 2024-02-14

2538 UNC-30/PITX coordinates neurotransmitter identity with postsynaptic GABA receptor clustering

Correa, E.; Mialon, M.; Cizeron, M.; Bessereau, J.-L.; Pinan-Lucarre, B.; Kratsios, P.

10.1101/2024.02.14.580278 — developmental biology — Posted on 2024-02-14

2539 Ramping cells in rodent mPFC encode time to past and future events via real Laplace transform

Cao, R.; Bright, I. M.; Howard, M. W.

10.1101/2024.02.13.580170 — neuroscience — Posted on 2024-02-14

2540 Characterizing directional dynamics of semantic prediction based on inter-regional temporal generalization

Mamashli, F.; Khan, S.; Hatamimajoumerd, E.; Jas, M.; Uluc, I.; Lankinen, K.; Obleser, J.; Friederici, A. D.; Maess, B.; Ahveninen, J.

10.1101/2024.02.13.580183 — neuroscience — Posted on 2024-02-14

2541 Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity

Liu, J.; Zaidi, A.; Pike, C. J.

10.1101/2024.02.13.580189 — neuroscience — Posted on 2024-02-14

2542 Trial-by-trial detection of cognitive events in neural time-series

Weindel, G.; van Maanen, L.; Borst, J. P.

10.1101/2024.02.13.580102 — neuroscience — Posted on 2024-02-14

2543 Contributions of sub-community based on short and long-range white matter tracts in personalized age-associated neurocompensatory mechanism

Chakraborty, P.; Saha, S.; Banerjee, A.; Roy, D.

10.1101/2024.02.12.580030 — neuroscience — Posted on 2024-02-14

2544 Monkey dorsolateral prefrontal cortex shows anatomically and functionally specific responses to sequential but not temporal or image changes

Rodriguez, N. Y.; Ahuja, A.; Basu, D.; Desrochers, T. M.

10.1101/2024.02.13.580192 — neuroscience — Posted on 2024-02-14

2545 Dissecting the contribution of vagal subcircuits in sepsis-induced brain dysfunctions.

Bourhy, L.; Moigneu, C.; Dupin, A.; Hecquet, E.; Levy, J.; Sharshar, T.; Lledo, P.-M.; Lepousez, G.

10.1101/2024.02.14.580156 — neuroscience — Posted on 2024-02-14

2546 Pheromone representation in the ant antennal lobe changes with age

Hart, T.; Lopes, L. E.; Frank, D. D.; Kronauer, D. J. C.

10.1101/2024.02.13.580193 — neuroscience — Posted on 2024-02-14

2547 The Lab Streaming Layer for Synchronized Multimodal Recording

Kothe, C.; Shirazi, S. Y.; Stenner, T.; Medine, D.; Boulay, C.; Crivich, M. I.; Mullen, T.; Delorme, A.; Makeig, S.

10.1101/2024.02.13.580071 — neuroscience — Posted on 2024-02-14

2548 Scaling Properties for Artificial Neural Network Models of a Small Nervous System

Simeon, Q.; Venancio, L. R.; Yang, G.; Boyden, E. S.; Nayebi, A.

10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-02-14

2549 Individual differences reveal similarities in serial dependencies across perceptual tasks, but no relation to serial dependencies for oculomotor behavior

Guan, S.; Goettker, A.

10.1101/2024.02.14.580238 — neuroscience — Posted on 2024-02-14

2550 DORSAL RAPHE NUCLEUS CONTROLS MOTIVATIONAL STATE TRANSITIONS IN MONKEYS

Priestley, L.; Chiew, M.; Shahdloo, M.; Mahmoodi, A.; Cheng, X.; Cleveland, R.; Rushworth, M.; Khalighinejad, N.

10.1101/2024.02.13.580224 — neuroscience — Posted on 2024-02-14

2551 Changes in mitochondrial distribution occur at the axon initial segment in association with neurodegeneration in Drosophila

Wodrich, A. P. K.; Harris, B. T.; Giniger, E.

10.1101/2024.02.14.580288 — neuroscience — Posted on 2024-02-14

2552 Focused Ultrasound modulates dopamine in a mesolimbic reward circuit

Olaitan, G.; Ganesana, M.; Lynch, W. J.; Legon, W.; Venton, B. J.

10.1101/2024.02.13.580202 — neuroscience — Posted on 2024-02-14

2553 Cost-benefit Tradeoff Mediates the Rule- to Memory-based Transition during Practice

Yang, G.; Jiang, J.

10.1101/2024.02.13.580214 — neuroscience — Posted on 2024-02-14

2554 Trappc9 deficiency causes obesity and fatty liver disease by constraining dopamine neurotransmission

Li, Y.; Usman, M.; Sapp, E.; Ke, Y.; Wang, Z.; Boudi, A.; DiFiglia, M.; Li, X.

10.1101/2024.02.13.580023 — neuroscience — Posted on 2024-02-14

2555 Plasticity of the Arabidopsis leaf lipidome and proteome in response to pathogen infection and heat stress

Scholz, P.; Doner, N.; Gutbrod, K.; Herrfurth, C.; Niemeyer, P. W.; Lim, M. S. S.; Blersch, K. F.; Schmitt, K.; Valerius, O.; Shanklin, J.; Feussner, I.; Doermann, P.; Braus, G.; Mullen, R. T.; Ischebeck, T.

10.1101/2024.02.09.579702 — plant biology — Posted on 2024-02-14

2556 Microenvironment Shapes Cell State, Plasticity, and Heterogeneity of Small Cell Lung Cancer

Desai, P. A.; Takahashi, N.; Kumar, R.; Nichols, S.; Malin, J.; Hunt, A.; Schultz, C.; Cao, Y.; Tillo, D.; Nousome, D.; Chauhan, L.; Sciuto, L.; Jordan, K.; Rajapakse, V.; Lissa, D.; Zhang, Y.; Kumar, S.; Pongor, L.; Singh, A.; Schroeder, B.; Sharma, A.; Chang, T.; Vilimas, R.; Pinkiert, D.; Graham, C.; Butcher, D.; Warmer, A.; Sebastian, R.; Mahon, M.; Baker, K.; Cheng, J.; Berger, A.; Lake, R.; Abel, M.; Krishnamurthy, M.; Chrisaffis, G.; Upadhyay, D.; Fitzgerald, P.; Nirula, M.; Goyal, S.; Atkinson, D.; Bateman, N. W.; Abulez, T.; Nair, G.; Apolo, A.; Guha, U.; Baktiar, K.; El Meskini, R.;

10.1101/2024.02.09.579028 — cancer biology — Posted on 2024-02-14

2557 A Tale of Two Chains: Geometries of a Chain Model and Protein Native State Structures

Skrbic, T.; Giacometti, A.; Hoang, T. X.; Maritan, A.; Banavar, J. R.

10.1101/2024.02.10.579771 — biophysics — Posted on 2024-02-14

2558 In Vitro/In Vivo Assessment of Aripiprazole-Loaded Thiolated Arabinoxylan based Nanoparticles: An Innovative Approach for Targeted Schizophrenia Therapy

Sikander, M.; tulain, u. r.; Malik, N. S.; Mahmood, A.; Erum, A.; Khan, M. T.; Safdar, A.

10.1101/2024.02.13.580125 — biochemistry — Posted on 2024-02-14

2559 Urinary Metabolomic Profile is Minimally Impacted by Common Storage Conditions and Additives

Weldon, K. C.; Panitchpakdi, M.; Caraballo-Rodriguez, A. M.; Wolfe, A. J.; Dorrestein, P. C.; Brubaker, L.; Burnett, L.

10.1101/2024.02.12.579937 — molecular biology — Posted on 2024-02-14

2560 Bifidobacterium longum subsp. longum BG-L47 boosts growth and activity of Limosilactobacillus reuteri DSM 17938 and its extracellular membrane vesicles

Ermann Lundberg, L.; Pallabi Mishra, P.; Liu, P.; Forsberg, M. M.; Sverremark-Ekström, E.; Grompone, G.; Hakansson, S.; Linninge, C.; Roos, S.

10.1101/2024.02.12.579962 — microbiology — Posted on 2024-02-14

2561 Time-varying Spatial Propagation of Brain Networks in fMRI data

Bostami, B.; Lewis, N.; Agcaoglu, O.; Turner, J. A.; van Erp, T. G. M.; Ford, J. M.; Calhoun, V.; Iraji, A.

10.1101/2024.02.12.579169 — neuroscience — Posted on 2024-02-14

2562 Cross-species real time detection of trends in pupil size fluctuation

Kronemer, S. I.; Gobo, V. E.; Teves, J. B.; Burk, D. C.; Shahsavarani, S.; Walsh, C. R.; Gonzalez-Castillo, J.; Bandettini, P. A.

10.1101/2024.02.12.579393 — neuroscience — Posted on 2024-02-14

2563 Natural Variation in Age-Related Dopamine Neuron Degeneration is Glutathione-Dependent and Linked to Life Span

Coleman, C. R.; Pallos, J.; Arreola-Bustos, A.; Wang, L.; Raftery, D.; Promislow, D. E. L.; Martin, I.

10.1101/2024.02.12.580013 — neuroscience — Posted on 2024-02-14

2564 Low-dimensional interference of mid-level sound statistics predicts human speech recognition in natural environmental noise

Clonan, A. C.; Zhai, X.; Stevenson, I. H.; Escabi, M. A.

10.1101/2024.02.13.579526 — neuroscience — Posted on 2024-02-14

2565 Same Sentences, Different Grammars, Different Brain Responses: An MEG study on Case and Agreement Encoding in Hindi and Nepali Split-Ergative Structures

Chacon, D. A.; Shrestha, S.; Dillon, B. W.; Bhatt, R.; Almeida, D.; Marantz, A.

10.1101/2024.02.12.579942 — neuroscience — Posted on 2024-02-14

2566 Aging disrupts blood-brain and blood-spinal cord barrier homeostasis, but does not increase paracellular permeability

Cummins, M. J.; Cresswell, E. T.; Smith, D. W.

10.1101/2024.02.12.580035 — neuroscience — Posted on 2024-02-14

2567 NMDAR-dependent supralinear dendritic integration in murine neurogliaform interneurons

Griesius, S.; Kullmann, D. M.

10.1101/2024.02.12.579998 — neuroscience — Posted on 2024-02-14

2568 Proteostasis as a fundamental principle of Tau immunotherapy

Cruz, E.; Nisbet, R. M.; Padmanabhan, P.; van Waardenberg, A.; Graham, M. E.; Nkajja, G.; Tapaswi, S.; Robinson, P.; Gotz, J.

10.1101/2024.02.12.580007 — neuroscience — Posted on 2024-02-14

2569 Identification of hippocampal area CA2 in hamster and vole brain

Siegler, P. N.; Shaughnessy, E. K.; Horman, B.; Vierling, T. T.; King, D. H.; Patisaul, H. B.; Huhman, K. L.; Alexander, G. M.; Dudek, S. M.

10.1101/2024.02.12.579957 — neuroscience — Posted on 2024-02-14

2570 MicroRNA-29a-5p Attenuates Oxygen-glucose Deprivation and Reoxygenation Injury in Astrocytes by Targeting Glycogen Synthase Kinase beta

Li, C.-L.; Zhang, J.-K.; Liu, Z.; Huang, Z.-R.; Xiang, C.; Shi, Z.-S.

10.1101/2024.02.13.580104 — neuroscience — Posted on 2024-02-14

2571 Task-guided Generative Adversarial Networks for Synthesizing and Augmenting Structural Connectivity Matrices for Connectivity-Based Prediction

Yamamoto, T.; Sugiura, T.; Hiroyasu, T.; Hiwa, S.

10.1101/2024.02.13.580039 — neuroscience — Posted on 2024-02-14

2572 Neural codes track prior events in a narrative and predict subsequent memory for details

Collin, S. H. P.; Kempner, R. P.; Srivatsan, S.; Norman, K. A.

10.1101/2024.02.13.580092 — neuroscience — Posted on 2024-02-14

2573 Atlas for the Lateralized Visuospatial Attention Networks (ALANs): Insights from fMRI and Network Analyses

Labache, L.; Petit, L.; Joliot, M.; Zago, L.

10.1101/2024.02.13.580164 — neuroscience — Posted on 2024-02-14

2574 Parsing Brain Network Specialization: A Replication and Expansion of Wang et al. (2014)

Peterson, M.; Floris, D. L.; Nielsen, J. A.

10.1101/2024.02.13.580153 — neuroscience — Posted on 2024-02-14

2575 Coexistence of asynchronous and clustered dynamics in noisy inhibitory neural networks

Feld, Y.; Hartmann, A.; Torcini, A.

10.1101/2024.02.13.580163 — neuroscience — Posted on 2024-02-14

2576 The spatial representation of temperature in the thalamus

Leva, T.; Whitmire, C.; Sauve, I.; Bokiniec, P.; Memler, C.; Horn, B.; Vestergaard, M.; Carta, M.; Poulet, J. F. A.

10.1101/2024.02.13.580167 — neuroscience — Posted on 2024-02-14

2577 How muscle synergies fail to solve the muscle redundancy problem during human reaching

Korol, A. S.; Gritsenko, V.

10.1101/2024.02.12.579990 — neuroscience — Posted on 2024-02-14

2578 DYRKP kinase regulates cell wall degradation in Chlamydomonas by inducing matrix metalloproteinase expression

Kim, M.; Jorge, G. L.; Aschern, M.; Cuine, S.; Huleux, M.; Mekhalfi, M.; Yang, J.-S.; Thelen, J. J.; Beisson, F.; Peltier, G.; Li-Beisson, Y.

10.1101/2024.02.09.579704 — plant biology — Posted on 2024-02-14

2579 Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discovery

Hanssen, F.; Garcia, M. U.; Folkersen, L.; Pedersen, A. S.; Lescai, F.; Jodoin, S.; Miller, E.; Seybold, M.; Wacker, O.; Smith, N.; nf-core community, ; Gabernet, G.; Nahnsen, S.

10.1101/2023.07.19.549462 — bioinformatics — Posted on 2024-02-14

2580 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats

Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.

10.1101/2023.08.10.552777 — ecology — Posted on 2024-02-14

2581 The rules of sex and strain: deciphering the chemical language of inbred and wild mouse conspecific scents

Nagel, M.; Niestroj, M.; Bansal, R.; Fleck, D.; Lampert, A.; Stopkova, R.; Stopka, P.; Ben-Shaul, Y.; Spehr, M.

10.1101/2023.06.24.546367 — neuroscience — Posted on 2024-02-14

2582 The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis

Luijten, I.; Onishi, A.; McKay, E. J.; Bengtsson, T.; Semple, R.

10.1101/2024.02.12.579851 — physiology — Posted on 2024-02-14

2583 Flowtigs: safety in flow decompositions for assembly graphs

Sena, F.; Ingervo, E.; Khan, S.; Prjibelski, A.; Schmidt, S.; Tomescu, A. I.

10.1101/2023.11.17.567499 — bioinformatics — Posted on 2024-02-14

2584 A haplotype-resolved reference genome of Quercus alba sheds light on the evolutionary history of oaks

Larson, D. A.; Staton, M. E.; Kapoor, B.; Faridi, N.; Zhebentyayeva, T.; Fan, S.; Stork, J.; Thomas, A.; Ahmed, A.; Stanton, E.; Houston, A.; Schlarbaum, S.; Hahn, M. W.; Carlson, J.; Abbott, A.; DeBolt, S.; Nelson, D.

10.1101/2024.02.13.579671 — genomics — Posted on 2024-02-14

2585 Instantaneous change in hyphal diameter in basidiomycete fungi

Mazheika, I. S.; Voronko, O. V.; Kolomiets, O. L.; Kamzolkina, O. V.

10.1101/2024.02.12.579893 — cell biology — Posted on 2024-02-14

2586 CDKs-mediated phosphorylation of PNKP is required for end processing of single-strand DNA gaps on Okazaki Fragments and genome stability

Tsukada, K.; Miyake, T.; Imamura, R.; Saikawa, K.; Saito, M.; Kase, N.; Ishiai, M.; Matsumoto, Y.; Shimada, M.

10.1101/2021.07.29.452278 — molecular biology — Posted on 2024-02-14

2587 A cellular and spatial atlas of TP53-associated tissue remodeling in lung adenocarcinoma

Zhao, W.; Kepecs, B.; Mahadevan, N. R.; Segerstolpe, A.; Weirather, J. L.; Besson, N. R.; Giotti, B.; Soong, B. Y.; Li, C.; Vigneau, S.; Slyper, M.; Wakiro, I.; Jane-Valbuena, J.; Ashenberg, O.; Rotem, A.; Bueno, R.; Rozenblatt-Rosen, O.; Pfaff, K.; Rodig, S.; Hata, A. N.; Regev, A.; Johnson, B. E.; Tsankov, A. M.

10.1101/2023.06.28.546977 — cancer biology — Posted on 2024-02-14

2588 Simultaneous multicolor fluorescence imaging using duplication-based PSF splitting

Van den Eynde, R.; Hertel, F.; Abakumov, S.; Krajnik, B.; Hugelier, S.; Auer, A.; Hellmeier, J.; Schlichthaerle, T.; Grattan, R. M.; Lidke, D. S.; Jungmann, R.; Leutenegger, M.; Vandenberg, W.; Dedecker, P.

10.1101/2022.10.04.510770 — biophysics — Posted on 2024-02-14

2589 A parametrized two-domain thermodynamic model explains diverse mutational effects on protein allostery

Liu, Z.; Gillis, T.; Raman, S.; Cui, Q.

10.1101/2023.08.06.552196 — biophysics — Posted on 2024-02-14

2590 A targetable N-terminal motif orchestrates α-synuclein oligomer to fibril conversion

Santos, J.; Cuellar, J.; Pallares, I.; Byrd, E. J.; Lends, A.; Moro, F.; Abdul-Shukkoor, M. B.; Pujols, J.; Velasco-Carneros, L.; Sobott, F.; Otzen, D. E.; Calabrese, A. N.; Muga, A.; Pedersen, J. S.; Loquet, A.; Valpuesta, J. M.; Radford, S.; Ventura, S.

10.1101/2023.02.10.527650 — biophysics — Posted on 2024-02-14

2591 Assessing the quality of de novo parasite genomes assembled using only Oxford Nanopore Technologies MinION data

Herzog, K. S.; Wu, R.; Hawdon, J. M.; Nejsum, P. S.; Favuer, J. R.

10.1101/2023.10.12.562065 — genomics — Posted on 2024-02-14

2592 Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing

John, M. S.; Chinnappan, M.; Artami, M.; Bhattacharya, M.; Keogh, R.; Kavanaugh, J.; Sharma, T.; Horswill, A. R.; Harris-Tryon, T. A.

10.1101/2024.02.10.579753 — microbiology — Posted on 2024-02-14

2593 Merging Multi-OMICs with Proteome Integral Solubility Alteration Unveils Antibiotic Mode of Action

Maity, R.; Zhang, X.; Liberati, F. R.; Ainsa, J. A.; Cutruzzola, F.; Rinaldo, S.; Sancho, J.; Scribani, C.; Gaetani, M.

10.1101/2023.09.07.556692 — microbiology — Posted on 2024-02-14

2594 Combining systems and synthetic biology for in vivo enzymology

Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.

10.1101/2024.02.02.578620 — systems biology — Posted on 2024-02-14

2595 Evolution of plant cell-type-specific cis-regulatory elements

Yan, H.; Mendieta, J. P.; Zhang, X.; Marand, A. P.; Liang, Y.; Luo, Z.; Minow, M. A. A.; Roule, T.; Wagner, D.; Tu, X.; Wang, Y.; Zhong, S.; Wessler, S. R.; Schmitz, R. J.

10.1101/2024.01.08.574753 — plant biology — Posted on 2024-02-14

2596 Solving the Pervasive Problem of Protocol Non-Compliance in MRI using an Open-Source tool mrQA

Sinha, H.; Raamana, P. R.

10.1101/2023.07.17.548591 — bioinformatics — Posted on 2024-02-14

2597 Prediction of A. thaliana's MCTP4 Structure using Deep Learning-Based tools and Exploration of Transmembrane domain Dynamics using Coarse-Grained Molecular Dynamics Simulations

Sritharan, S.; Versini, R.; Petit, J. D.; Bayer, E. E.; Taly, A.

10.1101/2023.08.04.552001 — bioinformatics — Posted on 2024-02-14

2598 Image processing tools for petabyte-scale light sheet microscopy data

Ruan, X.; Mueller, M.; Liu, G.; Görlitz, F.; Fu, T.-M.; Milkie, D. E.; Lillvis, J. L.; Kuhn, A.; Herr, C. Y. A.; Hercule, W.; Nienhaus, M.; Killilea, A. N.; Betzig, E.; Upadhyayula, S.

10.1101/2023.12.31.573734 — bioinformatics — Posted on 2024-02-14

2599 Feature Reuse and Scaling: Understanding Transfer Learning with Protein Language Models

Li, F.-Z.; Amini, A. P.; Yue, Y.; Yang, K. K.; Lu, A. X.

10.1101/2024.02.05.578959 — bioengineering — Posted on 2024-02-14

2600 Encapsulation of AAVs into protein vault nanoparticles as a novel solution to gene therapy's neutralizing antibody problem

Collins, L. T.; Beatty, W.; Moyo, B.; Alves-Bezerra, M.; Hurley, A.; Lou, Q.; Zhou, Z. H.; Lagor, W.; Bao, G.; Ponnazhagan, S.; McNally, R.; Rome, L.; Curiel, D.

10.1101/2023.11.29.569229 — bioengineering — Posted on 2024-02-14

2601 Reconstitution of cytolinker-mediated crosstalk between actin and vimentin

Isturiz Petitjean, I.; Tran, Q. D.; Goutou, A.; Kabir, Z.; Wiche, G.; Leduc, C.; Koenderink, G. H.

10.1101/2023.10.27.564417 — biochemistry — Posted on 2024-02-14

2602 X-Ray Structure and enzymatic study of a Bacterial NADPHoxidase highlight the activation mechanism of eukaryoticNOX

Petit-Hartlein, I.; Vermot, A.; Thepaut, M.; Humm, A.-S.; Dupeux, F.; Dupuy, J.; Chaptal, V.; Marquez, J. A.; Smith, S. M. E.; Fieschi, F.

10.1101/2023.10.16.562591 — biochemistry — Posted on 2024-02-14

2603 Cis-regulatory control of transcriptional timing and noise in response to estrogen

GInley-Hidinger, M.; Abewe, H.; Osborne, K.; Richey, A.; Kitchen, N.; Mortenson, K. L.; Wissink, E. M.; Lis, J.; Zhang, X.; Gertz, J.

10.1101/2023.03.14.532457 — genomics — Posted on 2024-02-14

2604 Insertion sequence driven evolution of the microbiota revealed by a novel metagenomics pipeline

Kirsch, J. M.; Hryckowian, A. J.; Duerkop, B. A.

10.1101/2023.10.06.561241 — genomics — Posted on 2024-02-14

2605 Body size shapes song in honeyeaters

Hay, E. M.; McGee, M. D.; White, C. R.; Chown, S. L.

10.1101/2023.06.20.545811 — evolutionary biology — Posted on 2024-02-14

2606 Local tree cover predicts mosquito species richness and disease vector presence in a tropical countryside landscape

Farner, J. E.; Howard, M. E.; Smith, J. R.; Anderson, C. B.; Mordecai, E. A.

10.1101/2023.12.05.570170 — ecology — Posted on 2024-02-14

2607 Estimating home range and temporal space use variability reveals age-related differences in risk exposure for reintroduced parrots

Forrest, S. W.; Rodriguez Recio, M.; Seddon, P. J.

10.1101/2022.12.17.520898 — ecology — Posted on 2024-02-14

2608 Epithelial Folding Irreversibility is Controlled by Elastoplastic Transition via Mechanosensitive Actin Bracket Formation

Teranishi, A.; Mori, M.; Ichiki, R.; Toda, S.; Shioi, G.; Okuda, S.

10.1101/2023.12.19.572470 — developmental biology — Posted on 2024-02-14

2609 HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

Xu, F.; Suyama, R.; Inada, T.; Kawaguchi, S.; Kai, T.

10.1101/2024.01.29.576963 — developmental biology — Posted on 2024-02-14

2610 Endogenous tagging using split mNeonGreen in human iPSCs for live imaging studies

Husser, M. C.; Pham, N. P.; Law, C.; Araujo, F. R. B.; Martin, V. J. J.; Piekny, A.

10.1101/2023.06.28.546942 — cell biology — Posted on 2024-02-14

2611 Brainstem Dbh+ Neurons Control Chronic Allergen-Induced Airway Hyperreactivity

Su, Y.; Xu, J.; Zhu, Z.; Ji, C.; Xu, L.; Yu, H.; Nudell, V. S.; Dash, B.; Moya, E.; Ye, L.; Nimmerjahn, A.; Sun, X.

10.1101/2023.02.04.527145 — cell biology — Posted on 2024-02-14

2612 Expression of elastin, FBXW2, fibrillin-1, and α-smooth muscle actin in damaged blood vessels of bovine legs

Akiyama, M.

10.1101/2024.02.06.579234 — cell biology — Posted on 2024-02-14

2613 Constitutive Plasma Membrane Turnover in T-REx293 cells via Ordered Membrane Domain Endocytosis under Mitochondrial Control

Deisl, C.; Moe, O. W.; Hilgemann, D. W.

10.1101/2024.01.17.576124 — cell biology — Posted on 2024-02-14

2614 Defective pgsA contributes to increased membrane fluidity and cell wall thickening in S. aureus with high-level daptomycin resistance

Freeman, C. D.; Hansen, T.; Urbauer, R. J. B.; Wilkinson, B. J.; Singh, V. K.; Hines, K. M.

10.1101/2023.04.11.536441 — microbiology — Posted on 2024-02-14

2615 A global survey of host, aquatic, and soil microbiomes reveals shared abundance and genomic features between bacterial and fungal generalists

Loos, D.; Pereira da Costa Filho, A.; Dutilh, B. E.; Barber, A. E.; Panagiotou, G.

10.1101/2022.11.15.515575 — microbiology — Posted on 2024-02-14

2616 Temporal sensitivity for achromatic and chromatic flicker across the visual cortex

Gentile, C. P.; Spitschan, M.; Taskin, H. O.; Bock, A. S.; Aguirre, G. K.

10.1101/2023.07.24.550403 — neuroscience — Posted on 2024-02-14

2617 Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

Caldi Gomes, L.; Hänzelmann, S.; Hausmann, F.; Khatri, R.; Oller, S.; Parvaz, M.; Tzeplaeff, L.; Pasetto, L.; Gebelin, M.; Ebbing, M.; Holzapfel, C.; Fabrizio Columbro, S.; Scozzari, S.; Knöferle, J.; Cordts, I.; Demleitner, A. F.; Deschauer, M.; Dufke, C.; Sturm, M.; Zhou, Q.; Zelina, P.; Sudria-Lopez, E.; Haack, T. B.; Streb, S.; Kuzma-Kozakiewicz, M.; Edbauer, D.; Pasterkamp, R. J.; Laczko, E.; Rehrauer, H.; Schlapbach, R.; Carapito, C.; Bonetto, V.; Bonn, S.; Lingor, P.

10.1101/2023.08.14.553180 — neuroscience — Posted on 2024-02-14

2618 Conduction Velocity, G-ratio, and Extracellular Water as Microstructural Characteristics of Autism Spectrum Disorder

Newman, B. T.; Jacokes, Z.; Venkadesh, S. T.; Webb, S. J.; Kleinhans, N. M.; McPartland, J. C.; Druzgal, T. J.; Pelphrey, K. A.; Van Horn, J. D.; For the GENDAAR Research Consortium,

10.1101/2023.07.23.550166 — neuroscience — Posted on 2024-02-14

2619 Minimal impact of proprioceptive loss on implicit sensorimotor adaptation and perceived movement outcome

Tsay, J. S.; Chandy, A. M.; Chua, R.; Miall, R. C.; Cole, J.; Farne, A.; Ivry, R. B.; Sarlegna, F. R.

10.1101/2023.01.19.524726 — neuroscience — Posted on 2024-02-14

2620 Joint inference of discrete cell types and continuous type-specific variability in single-cell datasets with MMIDAS

Marghi, Y.; Gala, R.; Baftizadeh, F.; Sumbul, U.

10.1101/2023.10.02.560574 — neuroscience — Posted on 2024-02-14

2621 Multiple brain activation patterns for the same task

Nakuci, J.; Yeon, J.; Haddara, N.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.

10.1101/2023.04.08.536107 — neuroscience — Posted on 2024-02-14

2622 A population code for idiothetic representations in the hippocampal-septal circuit

Etter, G.; van der Veldt, S.; Mosser, C.-A.; Hasselmo, M. E.; Williams, S.

10.1101/2023.11.10.566641 — neuroscience — Posted on 2024-02-14

2623 Odor and reward-evoked GABAergic neuronal activity in the basal forebrain influences olfactory-guided behavior in mice

Moss, E. H.; Tantry, E. K.; Le, E.; Brandel-Ankrapp, K.; Arenkiel, B. R.

10.1101/2022.09.04.506524 — neuroscience — Posted on 2024-02-14

2624 BMP signaling to pharyngeal muscle in the C. elegans response to a bacterial pathogen regulates anti-microbial peptide expression and pharyngeal pumping

Ciccarelli, E. J.; Bendelstein, M.; Yamamoto, K. K.; Reich, H.; Savage-Dunn, C.

10.1101/2023.03.06.531324 — physiology — Posted on 2024-02-14

2625 The cryo-EM structure of ASK1 reveals an asymmetric architecture allosterically modulated by TRX1

Honzejkova, K.; Kosek, D.; Obsilova, V.; Obsil, T.

10.1101/2023.12.20.572539 — biochemistry — Posted on 2024-02-14

2626 PSAP-genomic-regions: a method leveraging population data to prioritize coding and non-coding variants in whole genome sequencing for rare disease diagnosis

Ogloblinsky, M.-S.; Bocher, O.; Aloui, C.; Leutenegger, A.-L.; Ozisik, O.; Baudot, A.; Tournier-Lasserve, E.; Castillo-Madeen, H.; Lewinsohn, D.; Conrad, D. F.; Genin, E.; Marenne, G.

10.1101/2024.02.13.580050 — genetics — Posted on 2024-02-13

2627 Tick-borne zoonotic flaviviruses and Borrelia infections in wildlife hosts: what have field studies contributed?

Poisson, A.; Boulinier, T.; Bournez, L.; Gonzalez, G.; Migne, C. V.; Moutailler, S.; Faivre, B.; Metras, R.

10.1101/2023.08.25.554822 — ecology — Posted on 2024-02-14

2628 Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function.

Beigloo, F.; Davidson, C. J.; Gjonaj, J.; Perrine, S. A.; Kenney, J. W.

10.1101/2024.02.13.580160 — neuroscience — Posted on 2024-02-13

2629 Molecular signatures of cortical expansion in the human fetal brain

Ball, G.; Oldham, S.; Kyriakopoulou, V.; Williams, L. Z. J.; Karolis, V. R.; Price, A.; Hutter, J.; Seal, M. L.; Alexander-Bloch, A.; Hajnal, J. V.; Edwards, A. D.; Robinson, E. C.; Seidlitz, J.

10.1101/2024.02.13.580198 — neuroscience — Posted on 2024-02-13

2630 Enhancement of mediodorsal thalamus rescues aberrant belief dynamics in a mouse model with schizophrenia-associated mutation.

zhou, T.; Ho, Y.-Y.; Lee, R. X.; Fath, A. B.; He, K.; Scott, J.; Bajwa, N.; Hartley, N. D.; Wilde, J.; Gao, X.; Li, C.; Hong, E.; Nassar, M. R.; Wimmer, R. D.; Singh, T.; Halassa, M.; Feng, G.

10.1101/2024.01.08.574745 — neuroscience — Posted on 2024-02-14

2631 Optogenetic silencing hippocampal inputs to the retrosplenial cortex causes a prolonged disruption of working memory

Pinto-Correia, B.; Caldeira, P.; Remondes, M.

10.1101/2024.01.26.577365 — neuroscience — Posted on 2024-02-13

2632 The RNA-binding activity of the TRIM-NHL protein NHL-2 is essential for miRNA-mediated gene regulation

Saadat, N.; Colson, R. N.; Grimme, A. L.; Seroussi, U.; Anderson, J. W. T.; Claycomb, J. M.; Wilce, M. C.; McJunkin, K.; Wilce, J. A.; Boag, P. R.

10.1101/2024.02.13.580109 — genetics — Posted on 2024-02-13

2633 NMR based metabolomic workflow to unravel the molecular mechanisms involved in strawberry vernalization

Fernandez-Veloso, A.; Hiniesta-Valero, J.; Guerra-Castellano, A.; Tomas, L.; De la Rosa, M. A.; Diaz-Moreno, I.

10.1101/2024.02.13.580094 — biochemistry — Posted on 2024-02-13

2634 A selection of Golden Gate vectors to simplify recombinant protein production in Escherichia coli

Fairhead, M.; Koekemoer, L.; Williams, E.; von Delft, F.

10.1101/2024.02.13.579886 — molecular biology — Posted on 2024-02-13

2635 Delaying cefiderocol resistance development in NDM-producing Enterobacter cloacae complex by combining cefiderocol with aztreonam in vitro.

Goepel, L.; Tran Thanh, T.; Tran Nguyen, M. T.; Hauswaldt, S.; Nur Canbulat, O.; Rupp, J.; Boutin, S.; Nurjadi, D.

10.1101/2024.02.13.579981 — microbiology — Posted on 2024-02-13

2636 The transformation of sensory to perceptual braille letter representations in the visually deprived brain

Haupt, M.; Graumann, M.; Teng, S.; Kaltenbach, C.; Cichy, R. M.

10.1101/2024.02.12.579923 — neuroscience — Posted on 2024-02-13

2637 iSCORE-PD: an isogenic stem cell collection to research Parkinson Disease

Busquets, O.; Li, H.; Syed, K. M.; Jerez, P. A.; Dunnack, J.; Bu, R. L.; Verma, Y.; Pangilinan, G. R.; Martin, A.; Straub, J.; Du, Y.; Simon, V. M.; Poser, S.; Bush, Z.; Diaz, J.; Sahagun, A.; Gao, J.; Hernandez, D.; Levine, K. S.; Booth, E. O.; Bateup, H.; Rio, D.; Hockemeyer, D.; Blauwendraat, C.; Soldner, F.

10.1101/2024.02.12.579917 — neuroscience — Posted on 2024-02-13

2638 Intrinsic diving reflex induces potent antioxidative response by activation of NRF2 signaling

Powell, K.; Wadolowski, S.; Tambo, W.; Strohl, J. J.; Kim, D.; Turpin, J.; al-Abed, Y.; Brines, M.; Huerta, P. T.; Li, C.

10.1101/2024.02.12.579910 — physiology — Posted on 2024-02-13

2639 The transition state for coupled folding and binding of a disordered DNA binding domain resembles the unbound state

Kuravsky, M.; Kelly, C. F.; Redfield, C.; Shammas, S. L.

10.1101/2024.02.12.579954 — biophysics — Posted on 2024-02-13

2640 Unveiling Tryptophan Dynamics and Functions Across Model Organisms via Quantitative Imaging

Wang, K.; Chen, T.; Zhang, X.; Cao, J.; Wang, P.; Wang, M.; Du, J.-l.; Mu, Y.; Tao, R.

10.1101/2024.02.12.580012 — biochemistry — Posted on 2024-02-13

2641 Advanced Surface Passivation for High-Sensitivity Studies of Biomolecular Condensates

Yao, R.-W.; Rosen, M. K.

10.1101/2024.02.12.580000 — biochemistry — Posted on 2024-02-13

2642 Do light eaters live shorter lives? The case of ultralight Caenorhabditis elegans

Zhang, X.; Gharibi, H.; Beusch, C. M.; Meng, Z.; Saei Dibavar, A.; Gaetani, M.; Zubarev, R.

10.1101/2024.02.13.580069 — biochemistry — Posted on 2024-02-13

2643 Phosphorylation code of human nucleophosmin includes four cryptic sites for hierarchical binding of 14-3-3 proteins

Kapitonova, A. A.; Perfilova, K. V.; Cooley, R. B.; Sluchanko, N. N.

10.1101/2024.02.13.580064 — biochemistry — Posted on 2024-02-13

2644 Spatial top-down proteomics for the functional characterization of human kidney

Zemaitis, K. J.; Fulcher, J. M.; Kumar, R.; Degnan, D. J.; Lewis, L. A.; Liao, Y.-C.; Velickovic, M.; Williams, S. M.; Moore, R. J.; Bramer, L. M.; Velickovic, D.; Zhu, Y.; Zhou, M.; Pasa-Tolic, L.

10.1101/2024.02.13.580062 — biochemistry — Posted on 2024-02-13

2645 High-throughput nano-flow proteomics using a dual-column electrospray source

Staes, A.; Boucher, K.; Dufour, S.; Maia, T. M.; Timmerman, E.; Van Haver, D.; Pauwels, J.; Demol, H.; Vandenbussche, J.; Impens, F.; Devos, S.

10.1101/2024.02.13.580084 — biochemistry — Posted on 2024-02-13

2646 Optical tweezers reveal that PfEBA and PfRH ligands, not PfMSP1, play a central role in Plasmodium-falciparum merozoite-erythrocyte attachment

Kals, E.; Kals, M.; Lees, R. A.; Introini, V.; Kemp, A.; Silvester, E.; Collins, C. R.; Umrekar, T.; Kotar, J.; Cicuta, P.; Rayner, J. C.

10.1101/2024.02.13.580055 — molecular biology — Posted on 2024-02-13

2647 The N-terminal helix of MarA as a key element in the mechanism of DNA binding

Corbella, M.; Moreira, C.; Bello-Madruga, R.; Torrent, M.; Kamerlin, S. C. L.; Blair, J. M. A.; Sancho-Vaello, E.

10.1101/2024.02.13.580091 — molecular biology — Posted on 2024-02-13

2648 REV1 Coordinates a Multi-Faceted Tolerance Response to DNA Alkylation Damage and Prevents Chromosome Shattering in Drosophila melanogaster

Khodaverdian, V.; Sano, T.; Maggs, L.; Tomarchio, G.; Dias, A.; Clairmont, C.; Tran, M.; McVey, M.

10.1101/2024.02.13.580051 — molecular biology — Posted on 2024-02-13

2649 AMPK-activator ATX-304 reduces oxidative stress and improves MASLD via metabolic switching

Holm, E.; Vermeulen, I.; Parween, S.; Lopez-Perez, A.; Cillero-Pastor, B.; Vandenbosch, M.; Remeseiro, S.; Hörnblad, A.

10.1101/2024.02.13.578901 — molecular biology — Posted on 2024-02-13

2650 LbCas12-mediated multiplex gene editing and 2-fluoroadenine counter-selection in Phytophthora palmivora

Verhoeven, T.; Pluis, M. H.; Peippo, M.; Couillaud, G.; van den Berg, G. C.; Evangelisti, E.

10.1101/2024.02.13.580060 — microbiology — Posted on 2024-02-13

2651 The discovery of antimicrobial peptides from the gut microbiome of cockroach Blattella germanica using deep learning pipeline

Chen, S.; Qi, H.; Zhu, X.; Liu, T.; Teng, Y.; Gong, Q.; Jia, C.; Liu, T.

10.1101/2024.02.12.580024 — microbiology — Posted on 2024-02-13

2652 Bacteria use spatial sensing to direct chemotaxis on surfaces

Wheeler, J. H. R.; Foster, K. R.; Durham, W. M.

10.1101/2024.02.13.580113 — microbiology — Posted on 2024-02-13

2653 Detection, isolation and characterisation of phage-host complexes using BONCAT and click chemistry

Hellwig, P.; Dittrich, A.; Heyer, R.; Reichl, U.; Benndorf, D.

10.1101/2024.02.13.580147 — microbiology — Posted on 2024-02-13

2654 FakA impacts antiseptic susceptibility in Staphylococcus aureus and Enterococcus faecalis

Solsona Gaya, M.; Felgate, H.; Siani, H.; Whitchurch, C. B.; Webber, M. A.

10.1101/2024.02.13.580087 — microbiology — Posted on 2024-02-13

2655 Biological management, rather than chemical management, promotes the interaction between plants and their microbiome

Zhao, T.; Jia, X.; Liu, X.; Nepal, J.; Attard, E.; Guyoneaud, R.; Treder, K.; Pawlowska, A.; Michalowska, D.; Berg, G.; Stocker, F.; Cernava, T.; Elzenga, J. T. M.; Salles, J. F.

10.1101/2024.02.12.579901 — microbiology — Posted on 2024-02-13

2656 Investigating 3D microbial community dynamics in the rhizosphere using complex-field and fluorescence microscopy

Zhang, O.; Alcalde, R. E.; Zhou, H.; Yin, S.; Newman, D. K.; Yang, C.

10.1101/2024.02.13.578483 — microbiology — Posted on 2024-02-13

2657 Engineering multi-degrading bacterial communities to bioremediate soils contaminated with pesticides residues

Thieffry, S.; Aubert, J.; Devers-Lamrani, M.; Martin-Laurent, F.; Romdhane, S.; Rouard, N.; Siol, M.; Spor, A.

10.1101/2024.02.13.580075 — microbiology — Posted on 2024-02-13

2658 Chromatin structure and var2csa - a tango in regulation of var gene expression in the human malaria parasite Plasmodium falciparum?

Lenz, T.; Zhang, X.; Chakraborty, A.; Roayaei Ardakany, A.; Prudhomme, J.; Ay, F.; Deitsch, K.; Le Roch, K.

10.1101/2024.02.13.580059 — systems biology — Posted on 2024-02-13

2659 Variations in polarized trafficking of viral envelope proteins from insect-specific and insect-vectored viruses in insect midgut and salivary gland cells

Hodgson, J. J.; Chen, R. Y.; Blissard, G.; Buchon, N.

10.1101/2024.02.13.580057 — microbiology — Posted on 2024-02-13

2660 The regulatory network of the White Collar complex during early mushroom development in Schizophyllum commune

Vonk, P. J.; Van der Poel, M. J. P.; Niemeijer, Z. E.; Ohm, R. A.

10.1101/2024.02.13.580115 — microbiology — Posted on 2024-02-13

2661 In-host evolution of classic to convergent Klebsiella pneumoniae sequence type 147 isolates and impact of associated capsular changes on different morphotypes

Sydow, K.; Dogan, E.; Schwabe, M.; Heiden, S. E.; Khan, M. M.; Müller, J. U.; Bohnert, J. A.; Baecker, D.; Schlüter, R.; Schierack, P.; Eger, E.; Idelevich, E. A.; Becker, K.; Schaufler, K.

10.1101/2024.02.13.580130 — microbiology — Posted on 2024-02-13

2662 Human cytomegalovirus glycoprotein variants governing viral tropism and syncytium formation in epithelial cells and macrophages

Cimato, G.; Zhou, X.; Brune, W.; Frascaroli, G.

10.1101/2024.02.12.580040 — microbiology — Posted on 2024-02-13

2663 SARS-CoV-2 Omicron lineage XBB spike structures, conformations, antigenicity, and receptor recognition

Zhang, Q. E.; Lindenberger, J.; Parsons, R.; Thakur, B.; Parks, R.; Park, C. S.; Huang, X.; Sammour, S.; Janowska, K.; Spence, T. N.; Edwards, R. J.; Martin, M.; Williams, W. B.; Gobeil, S.; Montefiori, D. C.; Korber, B.; Saunders, K. O.; Haynes, B. F.; Haynes, B. F.; Henderson, R.; Acharya, P.

10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-02-13

2664 Identification of SARS-CoV-2 Mpro inhibitors through deep reinforcement learning for de novo drug design and computational chemistry approaches

Hazemann, J.; Kimmerlin, T.; Lange, R.; Sweeney, A. M.; Bourquin, G.; Ritz, D.; Czodrowski, P.

10.1101/2024.02.12.579977 — molecular biology — Posted on 2024-02-13

2665 The lateral habenula is required for maternal behavior in the mouse dam

Benedict, J.; Cudmore, R. H.; Linden, D. J.; Oden, D.; Spruell, A.

10.1101/2024.02.12.577842 — neuroscience — Posted on 2024-02-13

2666 Infer metabolic directions and magnitudes from moment differences of mass-weighted intensity distributions

Li, T.

10.1101/2024.02.12.579906 — bioinformatics — Posted on 2024-02-13

2667 Pseudotyped virus infection of multiplexed ACE2 libraries reveals SARS-CoV-2 variant shifts in receptor usage

Shukla, N.; Roelle, S. M.; Snell, J. C.; DelSignore, O.; Bruchez, A. M.; Matreyek, K.

10.1101/2024.02.13.580056 — genetics — Posted on 2024-02-13

2668 Glyoxalase 1: emerging biomarker and therapeutic target in cervical cancer progression

Kim, J.-Y.; Jung, J.-H.; Jung, S.; Lee, S.; Lee, H. A.; Ouh, Y.-T.; Hong, S.

10.1101/2024.02.11.579832 — cancer biology — Posted on 2024-02-13

2669 Biophysical Fluid Dynamics in a Petri Dish

Fortune, G. T.; Lauga, E.; Goldstein, R. E.

10.1101/2024.02.13.580063 — biophysics — Posted on 2024-02-13

2670 Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk

Wayman, J. A.; Yang, Z.; Angerman, E.; Bonkowski, E.; Jurickova, I.; Chen, X.; Bejjani, A. T.; Parks, L.; Parameswaran, S.; Miethke, A. G.; VanDussen, K. L.; Dhaliwal, J.; Weirauch, M. T.; Kottyan, L. C.; Denson, L. A.; Miraldi, E. R.

10.1101/2024.02.09.579678 — genomics — Posted on 2024-02-13

2671 Cranial sexual dimorphism levels in modern humans: Supporting a global expansion originating in southern Africa

Cenac, Z.

10.1101/2024.02.11.579824 — evolutionary biology — Posted on 2024-02-13

2672 Phages reconstitute NAD+ to counter bacterial immunity

Osterman, I.; Samra, H.; Rousset, F.; Loseva, E.; Itkin, M.; Malitsky, S.; Yirmiya, E.; Millman, A.; Sorek, R.

10.1101/2024.02.11.579819 — microbiology — Posted on 2024-02-13

2673 Abatacept treatment in LRBA deficient patients results in an increase in circulating FoxP3+ Helios + natural Treg

Donhauser, S.; Salzmann-Manrique, E.; Schubert, R.; Huenecke, S.; Bakhtiar, S.

10.1101/2024.02.10.579765 — immunology — Posted on 2024-02-13

2674 Identifying Reproducibly Important EEG Markers of Schizophrenia with an Explainable Multi-Model Deep Learning Approach

Lapera, M.; Ellis, C. A.; Miller, R. L.; Calhoun, V. D.

10.1101/2024.02.09.579600 — neuroscience — Posted on 2024-02-13

2675 Sapap3 knockout mice show threat bias under conflict during platform mediated avoidance task: implications for obsessive compulsive disorder

Manning, E. E.; Crummy, E. A.; LaPalombara, Z.; Li, X.; Manikandan, S.; Ahmari, S. E.

10.1101/2024.02.12.579940 — neuroscience — Posted on 2024-02-13

2676 Locus coeruleus injury modulates ventral midbrain neuroinflammation during DSS-induced colitis

Boles, J. S.; Holt, J.; Cole, C. L.; Neighbarger, N. K.; Urs, N. M.; Uriarte Huarte, O.; Tansey, M. G.

10.1101/2024.02.12.580010 — neuroscience — Posted on 2024-02-13

2677 Using high-resolution functional MRI to differentiate impacts of strabismic and anisometropic amblyopia on evoked ocular dominance activity in humans

Nasr, S.; Skerswetat, J.; Gaier, E. D.; Malladi, S. N.; Kennedy, B.; Tootell, R. B.; Bex, P.; Hunter, D. G.

10.1101/2024.02.11.579855 — neuroscience — Posted on 2024-02-13

2678 Mitochondrial bioenergetics stimulates autophagy for pathological tau clearance in tauopathy neurons

Jia, N.; Ganesan, D.; Guan, H.; Jeong, Y. Y.; Han, S.; Nissenbaum, M.; Kusnecov, A. W.; Cai, Q.

10.1101/2024.02.12.579959 — neuroscience — Posted on 2024-02-13

2679 Estimating orientation in Natural scenes: A Spiking Neural Network Model of the Insect Central Complex

Stentiford, R.; Knight, J. C.; Nowotny, T.; Philippides, A.; Graham, P.

10.1101/2024.02.13.580047 — neuroscience — Posted on 2024-02-13

2680 Assessing the effects of an 8-week mindfulness training program on neural oscillations and self-reports during meditation practice

Rodriguez Larios, J.; Foong Wong, K.; Lim, J.

10.1101/2024.02.09.579601 — neuroscience — Posted on 2024-02-13

2681 Delineating the shape of COPII coated membrane bud

Paul, S.; Audhya, A.; Cui, Q.

10.1101/2024.02.13.580145 — biophysics — Posted on 2024-02-13

2682 Wnt signaling modulates the response to DNA damage in the Drosophila wing imaginal disc by regulating the EGFR pathway

Ewen-Campen, B.; Perrimon, N.

10.1101/2024.02.13.580041 — genetics — Posted on 2024-02-13

2683 EMinsight: a tool to capture cryoEM microscope configuration and experimental outcomes for analysis and deposition.

Hatton, D.; Cha, J.; Riggs, S.; Harrison, P. J.; Thiyagalingam, J.; Clare, D. K.; Morris, K. L.

10.1101/2024.02.12.579963 — biophysics — Posted on 2024-02-13

2684 Complementary Cytoskeletal Feedback Loops Control Signal Transduction Excitability and Cell Polarity

Kuhn, J. A.; Banerjee, P.; Haye, A.; Robinson, D. N.; Iglesias, P. A.; Devreotes, P. N.

10.1101/2024.02.13.580131 — cell biology — Posted on 2024-02-13

2685 Identification of Mitosis Stages Using Artificial Neural Networks for 3D Time Lapse Cell Sequences

Dincer, T.; Stegmaier, J.; Jose, A.

10.1101/2024.02.12.579090 — cell biology — Posted on 2024-02-13

2686 Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

Garnsey, M. R.; Robinson, M. C.; Nguyen, L. T.; Cardin, R.; Tillotson, J.; Mashalidis, E.; Aijia, Y.; Aschenbrenner, L.; Balesano, A.; Behzadi, A.; Boras, B.; Chang, J. S.; Eng, H.; Ephron, A.; Foley, T.; Ford, K.; Frick, J. M.; Gibson, S.; Li, H.; Hurst, B.; Kalgutkar, A. S.; Korczynska, M.; Lengyel-Zhand, Z.; Liping, G.; Meredith, H. R.; Patel, N. C.; Polivkova, J.; Rai, D.; Rose, C. R.; Rothan, H.; Sakata, S. K.; Vargo, T. R.; Qi, W.; Wu, H.; Liu, Y.; Yurgelonis, I.; Zhang, J.; Zhu, Y.; Zhang, L.; Lee, A. A.

10.1101/2024.01.26.577395 — microbiology — Posted on 2024-02-13

2687 Discovery of a novel inhibitor of macropinocytosis with antiviral activity

Porebski, B.; Christ, W.; Corman, A.; Haraldsson, M.; Barz, M.; Lidemalm, L.; Haggblad, M.; Illmain, J.; Wright, S.; Murga, M.; Schlegel, J.; Sezgin, E.; Bhabha, G.; Lauschke, V. M.; Lafarga, M.; Klingstrom, J.; Huhn, D.; Fernandez-Capetillo, O.

10.1101/2023.10.25.563967 — pharmacology and toxicology — Posted on 2024-02-13

2688 The rasterdiv package for measuring diversityfrom space

Marcantonio, M.; Thouverai, E.; Rocchini, D.

10.1101/2024.02.07.579266 — ecology — Posted on 2024-02-13

2689 Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies

De Carli, A.; Kapelyukh, Y.; Kursawe, J.; Chaplain, M. A. J.; Wolf, C. R.; HAMIS, S. J.

10.1101/2023.12.12.571169 — cancer biology — Posted on 2024-02-13

2690 Divergent iron-regulatory states contribute to heterogeneity in breast cancer aggressiveness

Leineweber, W.; Rowell, M. Z.; Ranamukhaarachchi, S.; Walker, A. M.; Li, Y.; Villazon, J.; Farrera, A. M.; Hu, Z.; Yang, J.; Shi, L.; Fraley, S. I.

10.1101/2023.06.23.546216 — cancer biology — Posted on 2024-02-13

2691 Rapid growth and the evolution of complete metamorphosis in insects

Manthey, C.; Metcalf, J. C.; Monaghan, M. T.; Steiner, U. K.; Rolff, J.

10.1101/2024.02.12.579885 — evolutionary biology — Posted on 2024-02-13

2692 The last days of Aporia crataegi (L.) in Britain: evaluating genomic erosion in an extirpated butterfly

Whitla, R.; Hens, K.; Hogan, J.; Martin, G.; Breuker, C. J.; Shreeve, T. G.; Arif, S.

10.1101/2023.12.19.572305 — evolutionary biology — Posted on 2024-02-13

2693 Modern human expansion from (southern?) Africa: Origin, non-African ancestry, and linearity

Cenac, Z.

10.1101/2022.07.31.500977 — evolutionary biology — Posted on 2024-02-13

2694 Short internal open reading frames regulate the translation of N-terminally truncated proteoforms

Fettig, R.; Gonda, Z.; Walter, N.; Sallmann, P.; Thanisch, C.; Winter, M.; Bauer, S.; Zhang, L.; Linden, G.; Litfin, M.; Etard, C.; Armant, O.; Vazquez, O.; Kassel, O.

10.1101/2023.11.09.566418 — molecular biology — Posted on 2024-02-13

2695 Evaluating HIV Infectivity and Virion Maturation Across Varied Producer Cells with a Novel FRET-Based Detection and Quantification Assay

McGraw, A.; Choi, J.; Narayan, K.; Gujar, S. S.; Arnette, C. N.; Tibebe, H.; Bose, L. M.; Hillmer, G.; Sullivan, C.; Izumi, T.

10.1101/2023.12.25.573317 — microbiology — Posted on 2024-02-13

2696 Urban non-point source pollutants increases the biotic homogenization of the structure and function in river microbiome

Li, H.; Fan, X.; He, Z.; Fu, J.; Wu, J.; Wu, L.; Zhou, J.

10.1101/2023.08.21.553702 — microbiology — Posted on 2024-02-13

2697 The arginine/ornithine binding protein ArgT plays an essential role in Brucella to prevent intracellular killing and contribute to chronic persistence in the host

Mallik, S. R.; Joshi, K.; Radhakrishnan, G. K.

10.1101/2023.07.11.548583 — microbiology — Posted on 2024-02-13

2698 The selective force driving metabolic genes clustering

Fondi, M.; Pini, F.; Riccardi, C.; Gemo, P.; Brilli, M.

10.1101/2022.09.05.506644 — systems biology — Posted on 2024-02-13

2699 Phase diagrams of bone remodeling using a 3D stochastic cellular automaton

Heller, A. D.; Valleriani, A.; Cipitria, A.

10.1101/2023.12.21.572505 — systems biology — Posted on 2024-02-13

2700 NeuroVelo: interpretable learning of cellular dynamics from single-cell transcriptomic data

Kouadri Boudjelthia, I.; Milite, S.; El Kazwini, N.; Fernandez-Mateos, J.; Valeri, N.; Huang, Y.; Sottoriva, A.; Sanguinetti, G.

10.1101/2023.11.17.567500 — bioinformatics — Posted on 2024-02-13

2701 Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides

Jin, D.; Liang, S.; Shmatko, A.; Arnold, A.; Horst, D.; Gruenewald, T. G. P.; Gerstung, M.; Bai, X.

10.1101/2023.07.26.550748 — bioengineering — Posted on 2024-02-13

2702 Development and Validation of an MRI-Derived Head-Neck Finite Element Model

Bahreinizad, H.; Chowdhury, S. K.; Paulon, G.; Wei, L.; Santos, F.

10.1101/2023.02.12.528203 — bioengineering — Posted on 2024-02-13

2703 Wind Gates Search States in Free Flight

Stupski, S. D.; van Breugel, F.

10.1101/2023.11.30.569086 — animal behavior and cognition — Posted on 2024-02-13

2704 Tropical and montane Apis cerana show distinct dance-distance calibration curves

A K, B. K.; George, E. A.; Brockmann, A.

10.1101/2024.02.10.579752 — animal behavior and cognition — Posted on 2024-02-13

2705 Modularity of the segmentation clock and morphogenesis

Hammond, J. E.; Baker, R. E.; Verd, B.

10.1101/2024.01.08.574679 — developmental biology — Posted on 2024-02-13

2706 SLC-25A46 Regulates Mitochondrial Fusion through FZO-1/Mitofusin and is Essential for Maintaining Neuronal Morphology

Obinata, H.; Takahashi, H.; Shimo, S.; Oda, T.; Sugimoto, A.; Niwa, S.

10.1101/2024.02.11.579862 — cell biology — Posted on 2024-02-13

2707 Early life regulatory T cells modulate PPAR-gamma dependent skin pigmentation

Cho, I.; Xu, J. Z.; Aziz, H.; Lui, P. P.; Xie, B.; Tsai, P.-H.; Jeon, H.-Y.; Choi, J.; Ali, S.; Ali, N.

10.1101/2023.10.17.561843 — immunology — Posted on 2024-02-13

2708 Influence of chondroitin sulfate glycan sulfation patterns on histochemical labeling of perineuronal nets- a comparative study of interregional distribution in human and mouse brain

Belliveau, C.; Theberge, S.; Netto, S.; Rahimian, R.; Fakhfouri, G.; Hosdey, C.; Davoli, M. A.; Hendrickson, A.; Hao, K.; Giros, B.; Turecki, G.; Alonge, K. M.; Mechawar, N.

10.1101/2024.02.09.579711 — neuroscience — Posted on 2024-02-13

2709 Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

Zou, J.; Willem de Gee, J.; Mridha, Z.; Trinh, S.; Erskine, A.; Jing, M.; Yao, J.; Walker, S.; Li, Y.; McGinley, M.; Hires, S. A.

10.1101/2021.12.21.473699 — neuroscience — Posted on 2024-02-13

2710 A neuronal least-action principle for real-time learning in cortical circuits

Senn, W.; Dold, D.; Kungl, A.; Ellenberger, B.; Jordan, J.; Bengio, Y.; Sacramento, J.; Petrovici, M. A.

10.1101/2023.03.25.534198 — neuroscience — Posted on 2024-02-13

2711 Neuronal modeling of magnetoencephalography responses in auditory cortex to auditory and visual stimuli

Lankinen, K.; Ahveninen, J.; Jas, M.; Raij, T.; Ahlfors, S. P.

10.1101/2023.06.16.545371 — neuroscience — Posted on 2024-02-13

2712 Psilocybin induces dose-dependent changes in functional network organization in rat cortex

Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Mashour, G. A.; Vanini, G.; Pal, D.

10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-13

2713 Neurofeedback training can modulate task-relevant memory replay rate in rats

Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.

10.1101/2022.10.13.512183 — neuroscience — Posted on 2024-02-13

2714 Sensing, Feeling, and Regulating: Investigating the Association of Focal Brain Damage with Voluntary Respiratory and Motor Control

Bischoff, H.; Kovach, C. K.; Kumar, S.; Bruss, J.; Tranel, D.; Khalsa, S. S.

10.1101/2023.10.16.562254 — neuroscience — Posted on 2024-02-13

2715 Adapting to loss: A normative account of grief

Dulberg, Z.; Dubey, R.; Cohen, J. D.

10.1101/2024.02.06.578702 — neuroscience — Posted on 2024-02-13

2716 Circadian regulation of endoplasmic reticulum calcium response in mouse cultured astrocytes

Ryu, J. E.; Shim, K.-W.; Roh, H. W.; Park, M.; Lee, J.-H.; Kim, E. Y.

10.1101/2024.02.02.578616 — neuroscience — Posted on 2024-02-13

2717 Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum

Sears, R. M.; Andrade, E.; Samels, S. B.; Laughlin, L. C.; Moloney, D. M.; Wilson, D. A.; Alwood, M. R.; Moscarello, J. M.; Cain, C. K.

10.1101/2024.02.07.579321 — neuroscience — Posted on 2024-02-13

2718 Novel Mechanisms of Strigolactone-Induced DWARF14 Degradation in Arabidopsis thaliana

Sanchez Martin-Fontecha, E.; Cardinale, F.; Bürger, M.; Prandi, C.; Cubas, P.

10.1101/2024.01.10.574527 — plant biology — Posted on 2024-02-13

2719 Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity

Chhillar, H.; Yeh, P.-M.; Nguyen, H. H.; Jones, J. D.; Ding, P.

10.1101/2024.02.01.578334 — plant biology — Posted on 2024-02-13

2720 Protein-Cadmium Interactions in Crowded Biomolecular Environments Probed by In-celland Lysate NMR Spectroscopy

Katti, S. S.; Igumenova, T. I.

10.1101/2023.11.03.565546 — biophysics — Posted on 2024-02-13

2721 For antibody sequence generative modeling, mixture models may be all you need

Parkinson, J.; Wang, W.

10.1101/2024.01.27.577555 — bioinformatics — Posted on 2024-02-13

2722 Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies

Imomnazarov, K.; Lopez-Scarim, J.; Bagheri, I.; Joers, V.; Tansey, M. G.; Martin-Pena, A.

10.1101/2024.02.05.579034 — biochemistry — Posted on 2024-02-13

2723 The optimal clutch size revisited: separating individual quality from the costs of reproduction

Winder, L. A.; Simons, M. J. P.; Burke, T.

10.1101/2022.05.30.493969 — evolutionary biology — Posted on 2024-02-13

2724 Computer simulation and mathematical modeling of the interactions between ecological and sexual selection to reveal the mechanism of sympatric speciation

Lin, J.; Lin, J.; Wassall, N.

10.1101/2023.12.12.562603 — evolutionary biology — Posted on 2024-02-13

2725 Gastrulation-stage gene expression in Nipbl+/- mouse embryos foreshadows the development of syndromic birth defects

Chea, S.; Kreger, J.; Lopez-Burks, M. E.; MacLean, A. L.; Lander, A. D.; Calof, A.

10.1101/2023.10.16.558465 — developmental biology — Posted on 2024-02-13

2726 Eyespots originated multiple times independently across the Lepidoptera

Hanotte, B. P. F.; Willink, B.; Monteiro, A.

10.1101/2024.02.07.579046 — developmental biology — Posted on 2024-02-13

2727 Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion

Anaguano, D.; Adewale Fasoro, O.; Vick, G. S.; Blauwkamp, J. A.; Yanik, S.; Fierro, M. A.; Absalon, S.; SRINIVASAN, P.; Muralidharan, V.

10.1101/2024.01.29.577654 — cell biology — Posted on 2024-02-13

2728 Megakaryocyte maturation involves activation of the adaptive unfolded protein response

Faiz, M.; Kalev-Zylinska, M. L.; Singleton, D. C.; Hay, M. P.; Ledgerwood, E. C.

10.1101/2023.07.26.550730 — cell biology — Posted on 2024-02-13

2729 Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids

Guan, Y.; Fang, Z.; Hu, A.; Roberts, S.; Wang, M.; Ren, W.; Johansson, P. K.; Heilshorn, S. C.; Enejder, A.; Peltz, G.

10.1101/2023.04.25.538102 — cell biology — Posted on 2024-02-13

2730 Metabolic imprints in the hydrogen isotopes of Archaeoglobus fulgidus tetraether lipids

Rhim, J. H.; Kopf, S.; McFarlin, J.; Maloney, A.; Batther, H.; Harris, C. M.; Zhou, A.; Feng, X.; Weber, Y.; Hoeft-McCann, S.; Pearson, A.; Leavitt, W. D.

10.1101/2023.11.29.569324 — microbiology — Posted on 2024-02-13

2731 Consideration of sex as a biological variable in diabetes research across twenty years

Cherian, C. M.; Reeves, H.; De Silva, D.; Tsao, S.; Marshall, K. E.; Rideout, E. J.

10.1101/2023.06.13.544882 — scientific communication and education — Posted on 2024-02-13

2732 Fluorescence hybridization chain reaction enables localization of multiple molecular classes combined with plant cell ultrastructure

Yu, Y.; Huss, D. J.; Li, M. J.; Wickramanayake, J. S.; Belanger, S.; Klebanovych, A.; Meyers, B. C.; Kellogg, E. A.; Czymmek, K. J.

10.1101/2024.01.29.577761 — plant biology — Posted on 2024-02-13

2733 A hierarchy of metabolite exchanges in metabolic models of microbial species and communities

Wedmark, Y. K.; Vik, J. O.; Oyas, O.

10.1101/2023.09.05.556413 — systems biology — Posted on 2024-02-13

2734 A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer

Uo, T.; Ojo, K. K.; Sprenger, C. C.; Epilepsia, K. S.; Perera, B. G. K.; Damodarasamy, M.; Sun, S.; Kim, S.; Hogan, H. H.; Hulverson, M. A.; Choi, R.; Whitman, G. R.; Barrett, L. K.; Michaels, S. A.; Xu, L. H.; Sun, V. L.; Arnold, S. L. M.; Pang, H. J.; Nguyen, M. M.; Vigil, A.-L. B. G.; Kamat, V.; Sullivan, L. B.; Sweet, I. R.; Vidadala, R.; Maly, D. J.; Van Voorhis, W. C.; Plymate, S. R.

10.1101/2023.07.01.547355 — cancer biology — Posted on 2024-02-13

2735 Mechanical coupling with the nuclear envelope shapes the S. pombe mitotic spindle

Begley, M. A.; Pagan Medina, C.; Couture, T.; Zareiesfandabadi, P.; Rapp, M. B.; Tirfe, M.; LeBlanc, S.; Betterton, M. D.; Elting, M. W.

10.1101/2022.12.28.522145 — biophysics — Posted on 2024-02-13

2736 Joint cell type identification in spatial transcriptomics and single-cell RNA sequencing data

Geras, A.; Domzał, K.; Szczurek, E.

10.1101/2023.05.29.542559 — bioinformatics — Posted on 2024-02-13

2737 Sequence-to-sequence translation from mass spectra to peptides with a transformer model

Yilmaz, M.; Fondrie, W. E.; Bittremieux, W.; Nelson, R.; Ananth, V.; Oh, S.; Noble, W. S.; Melendez, C.

10.1101/2023.01.03.522621 — bioinformatics — Posted on 2024-02-13

2738 Multi-genome synteny detection using minimizer graph mappings

Coombe, L.; Kazemi, P.; Wong, J.; Birol, I.; Warren, R. L.

10.1101/2024.02.07.579356 — bioinformatics — Posted on 2024-02-13

2739 Fine-scale genetic structure and rare variant frequencies

Gagnon, L.; Moreau, C.; Laprise, C.; Girard, S. L.

10.1101/2024.02.02.578687 — genomics — Posted on 2024-02-13

2740 The last days of Aporia crataegi (L.) in Britain: evaluating genomic erosion in an extirpated butterfly

Whitla, R.; Hens, K.; Hogan, J.; Martin, G.; Breuker, C. J.; Shreve, T. G.; Arif, S.

10.1101/2023.12.19.572305 — evolutionary biology — Posted on 2024-02-13

2741 Substrate recognition principles for the PP2A-B55 protein phosphatase

Kruse, T.; Garvanska, D.; Varga, J. K.; Garland, W.; McEwan, B.; Hein, J.; Weisser, M. B.; Puy, I. B.; Chan, C.; Parrila, P. S.; Lopez-Mendez, B.; Jeyaprakash, A. A.; Schueler-Furman, O.; Jensen, T. H.; Kettenbach, A.; Nilsson, J.

10.1101/2024.02.10.579793 — cell biology — Posted on 2024-02-13

2742 Towards robust and generalizable representations of extracellular data using contrastive learning

Vishnubhotla, A.; Loh, C.; Paninski, L.; Srivastava, A.; Hurwitz, C. L.

10.1101/2023.10.30.564831 — neuroscience — Posted on 2024-02-13

2743 Female specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and Estrogen Receptor α

Molinaro, G.; Bowles, J. E.; Croom, K.; Gonzalez, D.; Mirjafary, S.; Birnbaum, S.; Razak, K. A.; Gibson, J. R.; Huber, K. M.

10.1101/2023.08.10.552857 — neuroscience — Posted on 2024-02-13

2744 Automated cell annotation in multi-cell images using an improved CRF_ID algorithm

Lee, H. J.; Liang, J.; Chaudhary, S.; Moon, S.; Yu, Z.; Wu, T.; Liu, H.; Choi, M.-K.; Zhang, Y.; Lu, H.

10.1101/2023.06.07.543949 — bioengineering — Posted on 2024-02-13

2745 AAV eluting lenses for single-step targeted expression of genetically- encoded activity sensors for in vivo microendoscopic calcium imaging

Jons, C.; Cheng, D.; Dong, C.; Meany, E. L.; Nassi, J.; Appel, E.

10.1101/2023.11.09.566491 — bioengineering — Posted on 2024-02-13

2746 One-step N-terminomics based on isolation of protein N-terminal peptides from LysargiNase digests by tip-based strong cation exchange chromatography

Morikawa, K.; Nishida, H.; Imami, K.; Ishihama, Y.

10.1101/2024.02.06.579163 — biochemistry — Posted on 2024-02-13

2747 How antisense transcripts can evolve to encode novel proteins

Iyengar, B. R.; Grandchamp, A.; Bornberg-Bauer, E.

10.1101/2023.08.30.555508 — evolutionary biology — Posted on 2024-02-13

2748 SMAD4 promotes somatic-germline contact during murine oocyte growth

Granados-Aparici, S.; Yang, Q.; Clarke, H. J.

10.1101/2023.08.31.555753 — developmental biology — Posted on 2024-02-13

2749 Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER

Jeremy, Y. C.; Tay, F.; Bennion, R. E.; Loss, O.; Maignel, J.; Pons, L.; Foster, K.; Beard, M.; Bard, F. A.

10.1101/2023.10.17.562749 — cell biology — Posted on 2024-02-13

2750 40 Hz Steady-State Response in Human Auditory Cortex Is Shaped by GABAergic Neuronal Inhibition

Toso, A.; Wermuth, A. P.; Arazi, A.; Braun, A.; Grent-'t Jong, T.; Uhlhaas, P. J.; Donner, T. H.

10.1101/2023.10.20.563259 — neuroscience — Posted on 2024-02-13

2751 Transcriptomics analyses of the LRRK2 protein interactome reveal distinct molecular signatures for sporadic and LRRK2 Parkinson's Disease

Zhao, Y.; Bracher-Smith, M.; Harvey, K.; Escott-Price, V.; Lewis, P. A.; Manzoni, C.

10.1101/2023.09.12.557373 — neuroscience — Posted on 2024-02-13

2752 Semaphorin7A patterns neural circuitry in the lateral line of the zebrafish

Dasgupta, A.; Reagor, C. C.; Paik, S. P.; Snow, L. M.; Jacobo, A.; Hudspeth, A.

10.1101/2022.11.17.516962 — neuroscience — Posted on 2024-02-13

2753 Activating SRC/MAPK signaling via 5-HT1A receptor contributes to the effect of vilazodone on improving thrombocytopenia

Zhou, L.; Ni, C.; Liao, R.; Tang, X.; Yi, T.; Ran, M.; Huang, M.; Liao, R.; Zhou, X.; Qin, D.; Wang, L.; Huang, F.; Xie, X.; Wan, Y.; Luo, J.; Wang, Y.; Wu, J.

10.1101/2023.12.16.571981 — pharmacology and toxicology — Posted on 2024-02-13

2754 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interactions during Primordial Follicle Activation

Takase, H. M.; Mishina, T.; Hayashi, T.; Yoshimura, M.; Kuse, M.; Nikaido, I.; Kitajima, T. S.

10.1101/2024.02.08.579446 — bioinformatics — Posted on 2024-02-13

2755 A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

Pyrihova, E.; King, M. S.; King, A. C.; Toleco, M. R.; van der Giezen, M.; Kunji, E. R. S.

10.1101/2023.11.02.565298 — biochemistry — Posted on 2024-02-13

2756 GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery

Perry, L. C.; CHARGE Consortium, ; Chevalier, N.; Luciano, M.

10.1101/2024.02.12.579907 — genetics — Posted on 2024-02-13

2757 Compensatory mutations potentiate constructive neutral evolution by gene duplication

Despres, P. C.; Dube, A. K.; Grenier, J.; Picard, M.-E.; Shi, R.; Landry, C. R.

10.1101/2024.02.12.579783 — evolutionary biology — Posted on 2024-02-13

2758 Sex differences in the relationship between maternal and foetal glucocorticoids in a free-ranging large mammal

Amin, B.; Fishman, R.; Quinn, M.; Matas, D.; Palme, R.; Koren, L.; Ciuti, S.

10.1101/2023.05.04.538920 — ecology — Posted on 2024-02-13

2759 A nociceptive amygdala-striatal pathway for chronic pain aversion

Wojick, J. A.; Paranjapye, A.; Chiu, J. K.; Mahmood, M.; Oswell, C.; Kimmey, B. A.; Wooldridge, L. M.; McCall, N. M.; Han, A.; Ejoh, L. L.; Chehimi, S. N.; Crist, R. C.; Reiner, B. C.; Korb, E.; Corder, G.

10.1101/2024.02.12.579947 — neuroscience — Posted on 2024-02-13

2760 The ChAHP chromatin remodelling complex regulates neurodevelopmental disorder risk genes to scale the production of neocortical layers

Clemot-Dupont, S.; Fernandes, J. A. L.; Larrigan, S.; Sun, X.; Medisetti, S.; Stanley, R.; El Hankouri, Z.; Joshi, S. V.; Picketts, D. J.; Shekhar, K.; Mattar, P.

10.1101/2024.02.12.579820 — neuroscience — Posted on 2024-02-13

2761 Short-term memory capacity predicts willingness to expend cognitive effort for reward

Forys, B. J.; Winstanley, C. A.; Kingstone, A.; Todd, R. M.

10.1101/2024.02.12.579951 — neuroscience — Posted on 2024-02-13

2762 Most axonal mitochondria in cortical pyramidal neuronslack mitochondrial DNA and consume ATP

Hirabayashi, Y.; Lewis, T. L.; Du, Y.; Virga, D. M.; Decker, A.; Coceano, G.; Alvelid, J.; Paul, M.; Hamilton, S.; Kneis, P.; Takahashi, Y.; Gaublomme, J.; Testa, I.; Polleux, F.

10.1101/2024.02.12.579972 — neuroscience — Posted on 2024-02-13

2763 Precision of the Integrated Cognitive Assessment for the assessment of neurocognitive performance in athletes

Glassbrook, D. J.; Chazot, P. L.; Hind, K.

10.1101/2023.03.22.533746 — neuroscience — Posted on 2024-02-13

2764 Cell-based assays and comparative genomics revealed the conserved and hidden effects of Wolbachia on insect sex determination

ARAI, H.; Herran, B.; Sugimoto, T. N.; Miyata, M.; Sasaki, T.; Kageyama, D.

10.1101/2024.02.12.579973 — microbiology — Posted on 2024-02-12

2765 Efficacy of Host Cell Serine Protease Inhibitor MM3122 against SARS-CoV-2 for Treatment and Prevention of COVID-19

Boon, A. C.; Bricker, T. L.; Fritch, E. J.; Leist, S. R.; Gully, K. L.; Baric, R. S.; Graham, R.; Troan, B. V.; Mahoney, M.; Janetka, J. W.

10.1101/2024.02.09.579701 — microbiology — Posted on 2024-02-12

2766 Phototropin connects blue light perception to starch metabolism in green algae

Yuan, Y.; Iannetta, A. A.; Kim, M.; Sadecki, P. W.; Arend, M.; Tsichla, A.; Ruiz-Sola, M. A.; Kepesidis, G.; Falconet, D.; Thevenon, E.; Tardif, M.; Brugiere, S.; Coute, Y.; Kleman, J.-P.; Sizova, I.; Schilling, M.; Jouhet, J.; Hegemann, P.; Li-Beisson, Y.; Nikoloski, Z.; Bastien, O.; Hicks, L. M.; Petroutsos, D.

10.1101/2024.02.12.579879 — plant biology — Posted on 2024-02-12

2767 KDM6A Regulates Immune Response Genes in Multiple Myeloma

Dupere-Richer, D.; Riva, A.; Maji, S.; Barwick, B. G.; Casella, H.; Sobh, A.; Quickstad, G.; Li, J.; de, u.; Piper, C.; Kulis, M.; Ezponda, T.; Martin-Subero, I.; Tonon, G.; Zhang, W.; Mitsiades, C.; Boise, L. H.; Bennett, R. L.; Licht, J. D.

10.1101/2024.02.12.579179 — cancer biology — Posted on 2024-02-12

2768 Nanoscale Structure, Interactions, and Dynamics of Centromere Nucleosomes

Filliaux, S. B.; Sun, Z.; Lyubchenko, Y. L.

10.1101/2024.02.12.579909 — biophysics — Posted on 2024-02-12

2769 nanoFeatures: a cross-platform application to characterize nanoparticles from super-resolution microscopy images

Izquierdo-Lozano, C.; van Noort, N.; van Veen, S.; Tholen, M. M. E.; Grisoni, F.; Albertazzi, L.

10.1101/2024.02.12.579898 — bioinformatics — Posted on 2024-02-12

2770 Antivirals for Monkeypox Virus: Proposing an Effective Machine/Deep Learning Framework

Hashemi, M.; Zabihian, A.; Hajsaeedi, M.; Hooshmand, M.

10.1101/2024.02.11.579829 — bioinformatics — Posted on 2024-02-12

2771 Surface tension-driven sorting of human perilipins on lipid droplets

Araujo, A. R. D.; Bello, A. A.; Bigay, J.; Franckhauser, C.; Gautier, R.; Cazareth, J.; Kovacs, D.; Brau, F.; Fuggetta, N.; Copic, A.; Antonny, B.

10.1101/2024.02.12.579497 — biochemistry — Posted on 2024-02-12

2772 Micromolar fluoride contamination arising from glass NMR tubes and a simple solution for biomolecular applications

Matwani, K.; Cornish, J.; DeBenedictis, E. A.; Heller, G. T.

10.1101/2024.02.12.579991 — biochemistry — Posted on 2024-02-12

2773 Enteropathogenic E. coli effector Map regulates the depletion of the tight junction proteins occludin and claudin-4 via cathepsin B and Rab13-mediated mechanisms

Mandal, A.; Walling, P.; Kansal, K.; Aijaz, S.

10.1101/2024.02.12.579967 — cell biology — Posted on 2024-02-12

2774 Transcriptional and post-transcriptional mechanisms modulate cyclopropane fatty acid synthase through small RNAs in Escherichia coli

Bianco, C.; Caballero-Rothar, N. N.; Ma, X.; Farley, K.; Vanderpool, C. K.

10.1101/2024.02.12.579971 — microbiology — Posted on 2024-02-12

2775 FABP4 as a Therapeutic Host Target Controlling SARS-CoV2 Infection

Baazim, H.; Koyuncu, E.; Tuncman, G.; Burak, M. F.; Merkel, L.; Bahour, N.; Karabulut, E.; Lee, G. Y.; Hanifehnezhad, A.; Karagoz, Z. F.; Foldes, K.; Engin, I.; Erman, A. G.; Oztop, S.; Filazi, N.; Gul, B.; Ceylan, A.; Cinar, O. O.; Can, F.; Kim, H.; Al-Hakeem, A.; Li, H.; Semerci, F.; Lin, X.; Yilmaz, E.; Ergonul, O.; Ozkul, A.; Hotamisligil, G. S.

10.1101/2024.02.10.579717 — microbiology — Posted on 2024-02-12

2776 Metabolites that feed upper glycolytic branches support glucose independent human cytomegalovirus replication

Mokry, R. L.; Purdy, J. G.

10.1101/2024.02.12.579992 — microbiology — Posted on 2024-02-12

2777 Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation

Blanco, A.; Coronado, R. A.; Arun, N.; Ma, K.; Dar, R. D.; Kieffer, C.

10.1101/2024.02.12.579955 — microbiology — Posted on 2024-02-12

2778 Targeted Viromes and Total Metagenomes Capture Distinct Components of Bee Gut Phage Communities

Sbardellati, D. L.; Vannette, R. L.

10.1101/2024.02.12.579852 — microbiology — Posted on 2024-02-12

2779 Vitamin B12 variants structure soil microbial communities despite soil's vast reservoir of B12.

Hallberg, Z. F.; Nicolas, A. M.; Alvarez-Aponte, Z. I.; Mok, K. C.; Sieradzki, E. T.; Pett-Ridge, J.; Banfield, J.; Carlson, H. K.; Firestone, M. K.; Taga, M. E.

10.1101/2024.02.12.580003 — microbiology — Posted on 2024-02-12

2780 DNA Methylome Regulates Virulence and Metabolism in Pseudomonas syringae

Huang, J.; Chen, F.; Lu, B.; Sun, Y.; Li, Y.; Hua, C.; Deng, X.

10.1101/2024.02.12.579912 — microbiology — Posted on 2024-02-12

2781 A new archaeal virus that suppresses the transcription of host immunity genes

Turgeman-Grott, I.; Golan, N.; Neri, U.; Naki, D.; Altman-Price, N.; Eizenshtein, K.; Choudhary, D. K.; Levy, R.; Papke, R. T.; Himani, H.; Reshef, L.; Gophna, U.

10.1101/2024.02.12.579488 — microbiology — Posted on 2024-02-12

2782 Genetic insertion of mouse Myxovirus-resistance gene 1 increases innate resistance against both high and low pathogenic avian influenza virus by significantly decreasing replication in chicken DF1 cell line

Briggs, K. R.; Chrzastek, K.; Segovia, K.; Mo, J.; Kapczynski, D.

10.1101/2024.02.12.579928 — immunology — Posted on 2024-02-12

2783 Pathways in the brain, heart, and lung influenced by SARS-CoV-2 NSP6 and SARS-CoV-2 regulated miRNAs: an in silico study hinting cancer incidence

Chatterjee, S.; Mahata, J.; Kateriya, S.; Anirudhan, G.

10.1101/2024.02.11.578752 — bioinformatics — Posted on 2024-02-12

2784 Dark respiration modulates photosynthetic carbon yield in cyanobacteria

Xie, N.; Sharma, C.; Rusche, K.; Wang, X.

10.1101/2024.02.12.579767 — biochemistry — Posted on 2024-02-12

2785 Intermolecular Energy Migration via HomoFRET Captures the Modulation in the Material Property of Phase-Separated Biomolecular Condensates

Joshi, A.; Walimbe, A.; Sarkar, S.; Arora, L.; Kaur, G.; Jhandai, P.; Chatterjee, D.; Banerjee, I.; Mukhopadhyay, S.

10.1101/2024.02.12.579899 — biophysics — Posted on 2024-02-12

2786 Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution

Kucukoglu, B.; Mohammed, I.; Guerrero-Ferreira, R. C.; Ribet, S.; Varnavides, G.; Leidl, M. L.; Lau, K.; Nazarov, S.; Myasnikov, A.; Sachse, C.; Mueller-Caspary, K.; Ophus, C.; Stahlberg, H.

10.1101/2024.02.12.579607 — biophysics — Posted on 2024-02-12

2787 nQuack: An R package for predicting ploidal level from sequence data using site-based heterozygosity

Gaynor, M. L.; Landis, J. B.; O'Connor, T. K.; Laport, R. G.; Doyle, J. J.; Soltis, D. E.; Ponciano, J. M.; Soltis, P. S.

10.1101/2024.02.12.579894 — bioinformatics — Posted on 2024-02-12

2788 One to rule them all? Assessing the performance of Forest Europe's biodiversity indicators against multitaxonomic data

Paillet, Y.; Zapponi, L.; Schall, P.; Monnet, J.-M.; Ammer, C.; Balducci, L.; Boch, S.; Brazaitis, G.; Campanaro, A.; Chianucci, F.; Doerfler, I.; Fischer, M.; Gosselin, M.; Gossner, M. M.; Heilmann-Clausen, J.; Hofmeister, J.; Hosek, J.; Kepfer-Rojas, S.; Odor, P.; Tinya, F.; Trentanovi, G.; Vacchiano, G.; Vandekerkhove, K.; Weisser, W. W.; Burrascano, S.

10.1101/2024.02.12.579875 — ecology — Posted on 2024-02-12

2789 SpoIIDMP-driven peptidoglycan rearrangement is crucial for ribosome translocation into the spore.

Iwanska, O.; Latoch, P.; Kovalenko, M.; Lichocka, M.; Holowka, J.; Serwa, R.; Grzybowska, A.; Zakrzewska-Czerwinska, J.; Starosta, A. L.

10.1101/2024.02.12.579902 — microbiology — Posted on 2024-02-12

2790 Human color constancy in cast shadows

Morimoto, T.; Sato, M.; Sunaga, S.; Uchikawa, K.

10.1101/2024.02.10.579744 — neuroscience — Posted on 2024-02-12

2791 Neurobiological slowdown in later life manifests in tempo of popular music

Luck, G.

10.1101/2024.02.06.579086 — neuroscience — Posted on 2024-02-12

2792 The BioRECIPE Knowledge Representation Format

Holtzapple, E.; Luo, H.; Tang, D.; Zhou, G.; Arazkhani, N.; Hansen, C.; Telmer, C. A.; Miskov-Zivanov, N.

10.1101/2024.02.12.579694 — systems biology — Posted on 2024-02-12

2793 RNAformer: A Simple Yet Effective Deep Learning Model for RNA Secondary Structure Prediction

Franke, J. K. H.; Runge, F.; Koeksal, R.; Backofen, R.; Hutter, F.

10.1101/2024.02.12.579881 — bioinformatics — Posted on 2024-02-12

2794 Direct, bisulfite-free 5mC and 5hmC sequencing at single-cell resolution

Chen, X.; Cheng, J.; Kong, L.; Shu, X.; Xu, H.; Inoue, M.; Berrocal, M. S. F.; Doskeland, D. S.; Sivakumar, S.; Liu, Y.; Ye, J.; Song, C.-X.

10.1101/2024.02.12.579864 — genomics — Posted on 2024-02-12

2795 Gene-edited primary muscle stem cells rescue dysferlin-deficient muscular dystrophy

Escobar Fernandez, H.; Di Francescantonio, S.; Marg, A.; Zhogov, A.; Krishna, S.; Metzler, E.; Petkova, M.; Daumke, O.; Kuehn, R.; Spuler, S.

10.1101/2024.02.12.579813 — genetics — Posted on 2024-02-12

2796 Rapid growth and the evolution of complete metamorphosis in insects

Manthey, C.; Metcalf, J. C.; Monaghan, M. T.; Steiner, U. K.; Rolff, J.

10.1101/2024.02.12.579885 — evolutionary biology — Posted on 2024-02-12

2797 Adaptation of turnip mosaic virus to Arabidopsis thaliana involves rewiring of VPg - host proteome interactions

Carrasco, J. L.; Gutierrez, P. A.; Elena, S. F.

10.1101/2024.02.12.579887 — evolutionary biology — Posted on 2024-02-12

2798 De novo ORFs are more likely to shrink than to elongate during neutral evolution.

Lebherz, M. K.; Iyengar, B. R.; Bornberg-Bauer, E.

10.1101/2024.02.12.579890 — evolutionary biology — Posted on 2024-02-12

2799 Instantaneous change in hyphal diameter in basidiomycete fungi

Mazheika, I. S.; Voronko, O. V.; Kolomiets, O. L.; Kamzolkina, O. V.

10.1101/2024.02.12.579893 — cell biology — Posted on 2024-02-12

2800 Sensing the bactericidal and bacteriostatic antimicrobial mode of action using Raman-Deuterium stable isotope probing (DSIP)

Karlo, J.; Vijay, A.; Phaneeswar, M. S.; Pratap Singh, S.

10.1101/2024.02.12.579891 — microbiology — Posted on 2024-02-12

2801 Deep learning-based Spatial Feature Extraction for Prognostic Prediction of Hepatocellular Carcinoma from Pathological Images

Hu, H.; Tan, T.; Liu, Y.; Liang, W.; Zhang, W.; Cui, J.; Song, J.; Li, X.

10.1101/2024.02.10.579571 — bioinformatics — Posted on 2024-02-12

2802 Reverse engineering placebo analgesia

Chen, B.; Goldstein, N.; Dziubek, J.; Zhao, S.; Harrahill, A.; Sundai, A.; Choi, S.; Prevosto, V.; Wang, F.

10.1101/2024.02.12.579946 — neuroscience — Posted on 2024-02-12

2803 Functional architecture of intracellular oscillations in hippocampal dendrites

Liao, Z.; Gonzalez, K. C.; Li, D.; Yang, C.; Holder, D.; McClain, N.; Zhang, G.; Evans, S.; Chavarha, M.; Yi, J.; Makinson, C.; Lin, M.; Losonczy, A.; Negrean, A.

10.1101/2024.02.12.579750 — neuroscience — Posted on 2024-02-12

2804 Enhancement of Temporal Processing via Transcutaneous Vagus Nerve Stimulation

Bahadori, M.; Bhutani, N.; Bella, S. D.

10.1101/2024.02.12.579950 — neuroscience — Posted on 2024-02-12

2805 Effects of Turbidity and Habitat Complexity on the Foraging Behavior of the Black Bullhead (Ameiurus melas)

Preiszner, B.; Szolnoki, A.; Czegledi, I.; Eros, T.

10.1101/2024.02.12.579876 — animal behavior and cognition — Posted on 2024-02-12

2806 Psilocybin induces dose-dependent changes in functional network organization in rat cortex

Silverstein, B. H.; Kolbman, N.; Nelson, A.; Liu, T.; Guzzo, P.; Gilligan, J.; Lee, U.; Vanini, G.; Pal, D.

10.1101/2024.02.09.579718 — neuroscience — Posted on 2024-02-12

2807 Age-dependent dynamics of neuronal VAPBALS inclusions in the adult brain

Thulasidharan, A.; Garg, L.; Tendulkar, S.; Ratnaparkhi, G. S.

10.1101/2024.02.12.579854 — neuroscience — Posted on 2024-02-12

2808 Zapit: Open Source Random-Access Photostimulation For Neuroscience

Lohse, M.; Gauld, O. M.; Skretowska, M. T.; Vincent, P.; Pajot-Moric, Q.; Townsend, S.; Duan, C. A.; Akrami, A.; Mrsic-Flogel, T. D.; Campbell, R. A.

10.1101/2024.02.12.579892 — neuroscience — Posted on 2024-02-12

2809 A latent pool of neurons silenced by sensory-evoked inhibition can be recruited to enhance perception

Gauld, O. M.; Packer, A. M.; Russell, L. E.; Dalgleish, H. W. P.; Iuga, M.; Sacadura, F.; Roth, A.; Clark, B. A.; Hausser, M.

10.1101/2024.02.12.579847 — neuroscience — Posted on 2024-02-12

2810 Intercalated amygdala dysfunction drives extinction deficits in the Sapap3 mouse model of obsessive-compulsive disorder

St. Laurent, R.; Kusche, K. M.; Kreitzer, A. C.; Malenka, R. C.

10.1101/2024.02.12.578709 — neuroscience — Posted on 2024-02-12

2811 The impact of face masks on face-to-face neural tracking of speech: auditory and visual obstacles

Fantoni, M.; Federici, A.; Camponogara, I.; Handjaras, G.; Martinelli, A.; Bednaya, E.; Ricciardi, E.; Pavani, F.; Bottari, D.

10.1101/2024.02.12.577414 — neuroscience — Posted on 2024-02-12

2812 Continuous Bump Attractor Networks Require Explicit Error Coding for Gain Recalibration

Secer, G.; Knierim, J. J.; Cowan, N. J.

10.1101/2024.02.12.579874 — neuroscience — Posted on 2024-02-12

2813 Amelioration of signalling deficits underlying metabolic shortfall in TREM2R47H human iPSC-derived microglia

Vasilopoulou, F.; Piers, T. M.; Jingzhang, W.; Hardy, J.; Pocock, J. M.

10.1101/2024.02.12.579896 — neuroscience — Posted on 2024-02-12

2814 How to design optimal brain stimulation to modulate phase-amplitude coupling?

Duchet, B.; Bogacz, R.

10.1101/2024.02.12.579897 — neuroscience — Posted on 2024-02-12

2815 Iguanas from above: Citizen scientists provide reliable counts of endangered Galapagos marine iguanas from drone imagery

Varela-Jaramillo, A.; Winkelmann, C.; Rivas-Torres, G.; Guayasamin, J. M.; Steinfartz, S.; MacLeod, A.

10.1101/2024.02.09.579637 — zoology — Posted on 2024-02-12

2816 Proteomic profiling of intracranial atherosclerotic plaque in the human brain

Hao, Q.; Wang, E.; Wang, J.; Wu, Z.; Crary, J. F.; Sharma, S.; Thorn, E. L.; Elahi, F.; Zhang, B.; Peng, J.

10.1101/2024.02.10.579787 — systems biology — Posted on 2024-02-12

2817 An Organism-Level Quantitative Flux Model of Mammalian Energy Metabolism

Yuan, B.; Inouye, K. E.; Hotamisligil, G.; Hui, S.

10.1101/2024.02.11.579776 — systems biology — Posted on 2024-02-12

2818 Selective enrichment of high-affinity clade II N2O-reducers in a mixed culture

Laureni, M.; Corbera Rubio, F.; Kim, D. D.; Browne, S.; Roothans, N.; Weissbrodt, D. G.; Olavarria, K. O.; de Jonge, N.; Yoon, S.; Pabst, M.; van Loosdrecht, M. C. M.

10.1101/2024.02.09.579283 — systems biology — Posted on 2024-02-12

2819 Key unprotected areas for carnivore conservation in Mexico

Gonzalez, G. I.; Harris, N. C.

10.1101/2024.02.10.579669 — ecology — Posted on 2024-02-12

2820 Two distinct mechanisms for Nav1.7 null analgesia

Kanellopoulos, A.; Tian, N.; Cox, J. J.; Zhao, J.; Woods, G.; Wood, J.

10.1101/2024.02.12.579826 — neuroscience — Posted on 2024-02-12

2821 Modeling Hereditary Diffuse Leukoencephalopathy with Axonal Spheroids using microglia-sufficient brain organoids

Wong, W. J.; Zhu, Y.; Wang, H.; Qian, J. W.; Li, Z.; Song, L.; Liu, Z.; Wei, G.; Zhang, S. Y.; Su, B.; Ping, H. F.; Wang, K.; Ginhoux, F.

10.1101/2024.02.12.579869 — neuroscience — Posted on 2024-02-12

2822 Chemogenetic activation of microglial Gi signaling decreases microglial surveillance and impairs neuronal synchronization

Zhao, S.; Wang, L.; Liang, Y.; Zheng, J.; Umpierre, A. D.; Wu, L.-J.

10.1101/2024.02.12.579861 — neuroscience — Posted on 2024-02-12

2823 Inferring Metabolic Objectives and Tradeoffs in Single Cells During Embryogenesis

Lin, D.-W.; Zhang, L.; Zhang, J.; Chandrasekaran, S.

10.1101/2024.02.09.579737 — systems biology — Posted on 2024-02-12

2824 Historic breeding practices contribute to germplasm divergence in leaf specialized metabolism and ecophysiology in cultivated sunflower (Helianthus annuus).

Dowell, J.; Bowsher, A.; Jamshad, A.; Shah, R.; Burke, J. M.; Donovan, l.; mason, c.

10.1101/2024.02.09.579651 — plant biology — Posted on 2024-02-12

2825 Investigating the cis-Regulatory Basis of C3 and C4 Photosynthesis in Grasses at Single-Cell Resolution

Mendieta, J. P.; Tu, X.; Yan, H.; Zhang, X.; Marrand, A. P.; Zhong, S.; Schmitz, R. J.

10.1101/2024.01.05.574340 — plant biology — Posted on 2024-02-12

2826 Intrauterine Growth-Restricted Pregnant Rats, from Hypertensive Placental Ischemic Dams Display Preeclamptic-like Symptoms: A New Rodent Model of Preeclampsia

Smith, J.; Powell, M.; Cromartie, W.; Smith, S.; Jones, K.; Castillo, A.; Shaw, J.; Editone, J.; Howard-Cunningham, A.; Tatum, R.; Smith, A. N.; Fisher, B.; Booz, G. W.; CUNNINGHAM, M. W.

10.1101/2024.02.07.579407 — physiology — Posted on 2024-02-12

2827 The metabolically protective energy expenditure increase of Pik3r1-related insulin resistance is not explained by Ucp1-mediated thermogenesis

Luijten, I.; Onishi, A.; McKay, E. J.; Bengtsson, T.; Semple, R.

10.1101/2024.02.12.579851 — physiology — Posted on 2024-02-12

2828 Electrophysiological Effects Of Kappa-Opioid Analgesic, RU-1205, Using Machine Learning Methods

Kalitin, K. Y.; Mukha, O. Y.; Spasov, A. A.

10.1101/2024.02.11.579812 — pharmacology and toxicology — Posted on 2024-02-12

2829 Synthesis and Biological Evaluation of Novel MB327 Analogs as Resensitizers for Desensitized Nicotinic Acetylcholine Receptors after Intoxication with Nerve Agents

Bernauer, T.; Nitsche, V.; Kaiser, J.; Gertzen, C. G. W.; Hoefner, G.; Niessen, K. V.; Seeger, T.; Steinritz, D.; Worek, F.; Gohlke, H.; Wanner, K. T.; Paintner, F. F.

10.1101/2024.02.09.579646 — pharmacology and toxicology — Posted on 2024-02-12

2830 Enhancing Bone Regeneration and Osseointegration using rhPTH(1-34) and Dimeric R25CPTH(1-34) in an Osteoporotic Beagle Model

Shin, J.-O.; Lee, J.-b.; Lee, S.; Kim, J.

10.1101/2024.02.10.579779 — pathology — Posted on 2024-02-12

2831 Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts

Tariq, A.; Piontkivska, H.

10.1101/2024.02.10.579760 — bioinformatics — Posted on 2024-02-12

2832 ATP13A1 engages GET3 to facilitate substrate-specific translocation

Yang, X.; Li, T.; Fang, Z.; Feng, Z.; Zou, Y.

10.1101/2024.02.12.579870 — biochemistry — Posted on 2024-02-12

2833 Describing interdomain communication and allostery in full-length FXR

Hazarika, S.; Yu, T.; Dube, N.; Villalona, P.; Okafor, C. D.

10.1101/2024.02.10.579785 — biochemistry — Posted on 2024-02-12

2834 Serotonin deficiency from constitutive SKN-1 activation drives pathogen apathy.

Nair, T.; Weathers, B.; Stuhr, N.; Nahn, J.; Curran, S. P.

10.1101/2024.02.10.579755 — genetics — Posted on 2024-02-12

2835 A micro-RNA drives a 100-million-year adaptive evolution of melanic patterns in butterflies and moths

Tian, S.; Banerjee, T. D.; Wee, J. L. Q.; Wang, Y.; Murugesan, S. N.; Monteiro, A.

10.1101/2024.02.09.579741 — genetics — Posted on 2024-02-12

2836 Unselfish meiotic drive maintains heterozygosity in a parthenogenetic ant

Lacy, K. D.; Hart, T.; Kronauer, D. J. C.

10.1101/2024.02.09.579553 — evolutionary biology — Posted on 2024-02-12

2837 Community density patterns estimated by species distribution modeling: the case study of an insect virus interaction

Dupas, S.; Zeddam, J.-L.; Orbe, K.; Barrera Cubillos, G. P.; Villamizar, L. F.; Mora, P.; Suquillo, J.; Dangles, O.; Lopez Avilla, A.; Cotes Prado, A. M.; Silvain, J.-F.

10.1101/2024.02.08.579470 — ecology — Posted on 2024-02-12

2838 Zebrafish reveal new roles for Fam83f in hatching and the DNA damage-mediated autophagic response

Jones, R. A.; Cooper, F.; Kelly, G.; Barry, D.; Renshaw, M. J.; Sapkota, G.; Smith, J. C.

10.1101/2024.02.10.579757 — developmental biology — Posted on 2024-02-12

2839 Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells

Boudjema, A.-R.; Balague, R.; Jewett, C. E.; LoMastro, G. M.; Mercy, O.; Al Jord, A.; Faucourt, M.; Schaeffer, A.; Nous, C.; Delgehyr, N.; Holland, A. J.; Spassky, N.; Meunier, A.

10.1101/2024.02.09.579615 — cell biology — Posted on 2024-02-12

2840 Chronic alcohol exposure induces cerebral microbleeds by TGF-β1/Smad signaling pathway mediated remodeling of cerebral small vessels

Lu, H.; Wang, H.; Li, X.; Lin, X.; Li, C.; Chen, W.; Zou, L.; Pan, J.; Zhang, X.; He, L.; Rong, X.; Peng, Y.

10.1101/2024.02.07.579406 — molecular biology — Posted on 2024-02-12

2841 Human coronavirus 229E infection inactivates pyroptosis executioner gasdermin D but ultimately leads to lytic cell death partly mediated by gasdermin E

Martianez-Vendrell, X.; Bloeme, J.; Hutchinson, R.; Guy, C.; Bowie, A.; Kikkert, M.

10.1101/2024.02.09.579628 — microbiology — Posted on 2024-02-12

2842 IL-17C plays a role in the pathophysiology of acute recurrent tonsillitis

Clapperton, M.; Kunanandam, T.; Florea, C. D.; Cunningham, M. R.; Douglas, C.; McConnell, G.

10.1101/2024.02.08.578879 — immunology — Posted on 2024-02-12

2843 Streptavidin-drug conjugates streamline optimization of antibody-based conditioning for hematopoietic stem cell transplantation

Yelamali, A. R.; Chendamarai, E.; Ritchey, J. K.; Rettig, M. P.; DiPersio, J. F.; Persaud, S. P.

10.1101/2024.02.12.579199 — immunology — Posted on 2024-02-12

2844 Rational Design of Monomeric IL37 Variants Guided by Stability and Dynamical Analyses of IL37 Dimers

Sardag, I.; Duvenci, Z. S.; Belkaya, S.; Timucin, E.

10.1101/2024.02.06.579100 — immunology — Posted on 2024-02-12

2845 In mice, discrete odors can selectively promote the neurogenesis of sensory neuron subtypes that they stimulate

Hossain, K.; Smith, M.; Santoro, S. W.

10.1101/2024.02.10.579748 — neuroscience — Posted on 2024-02-12

2846 Extracellular disposal of nuclear waste by APP: a protective mechanism impaired in Alzheimer's disease

Dougnon, G.; Otsuka, T.; Nakamura, Y.; Sakai, A.; Yamanaka, T.; Matsui, N.; Nakahara, A.; Ito, A.; Hatano, A.; Matsumoto, M.; Igarashi, H.; Kakita, A.; Ueno, M.; Matsui, H.

10.1101/2024.02.10.579739 — neuroscience — Posted on 2024-02-12

2847 Influence of insulin sensitivity on food cue evoked functional brain connectivity in children

Semeia, L.; Veit, R.; Zhao, S.; Luo, S.; Angelo, B.; Birkenfeld, A. L.; Preissl, H.; Xiang, A. H.; Kullmann, S.; Page, K. A.

10.1101/2024.02.12.579924 — neuroscience — Posted on 2024-02-12

2848 Dorsal Raphe to Basolateral Amygdala Corticotropin-Releasing Factor Circuit Regulates Cocaine-Memory Reconsolidation

Ritchie, J. L.; Qi, S.; Soto, D. A.; Swatzell, S. E.; Grenz, H. I.; Pruitt, A. Y.; Artimenia, L. M.; Cooke, S. K.; Berridge, C. W.; Fuchs, R. A.

10.1101/2024.02.10.579725 — neuroscience — Posted on 2024-02-12

2849 Investigating EMT-mediated resistance to EGFR tyrosine kinase inhibitors in NSCLC using innovative organoid models

Kobayashi, N.; Katakura, S.; Fukuda, N.; Teranishi, S.; Kubo, S.; Kamimaki, C.; Matsumoto, H.; Somekawa, K.; Kaneko, A.; Ishikawa, Y.; Okudela, K.; Sekine, K.; Kaneko, T.

10.1101/2024.02.08.579426 — cancer biology — Posted on 2024-02-12

2850 Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties

Boutzen, H.; Murison, A.; Wang, J. C. Y.; Arlidge, C.; Lupien, M.; Kaufmann, K. B.; Dick, J. E.

10.1101/2024.02.09.579319 — cancer biology — Posted on 2024-02-12

2851 Supramodal neural information supports stimulus-driven attention across cortical levels

Niedernhuber, M.; Fardo, F.; Allen, M.; Bekinschtein, T.

10.1101/2024.02.12.578256 — neuroscience — Posted on 2024-02-12

2852 Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Sternberg, C.; Limberger, T.; Raigel, M.; Trachtova, K.; Schlederer, M.; Lindner, D.; Kodajova, P.; Yang, J.; Ziegler, R.; Neubauer, H. A.; Dey, S.; Redmer, T.; Stoiber, S.; Hejret, V.; Tichy, B.; Tomberger, M.; Harbusch, N. S.; Tangermann, S.; Oberhuber, M.; Bystry, V.; Persson, J. L.; Pospisilova, S.; Wolf, P.; Sternberg, F.; Hoegler, S.; Lagger, S.; Rose-John, S.; Kenner, L.

10.1101/2024.02.11.579838 — cancer biology — Posted on 2024-02-12

2853 Influence of chondroitin sulfate glycan sulfation patterns on histochemical labeling of perineuronal nets- a comparative study of interregional distribution in human and mouse brain

Belliveau, C.; Theberge, S.; Netto, S.; Rahimian, R.; Fakhfouri, G.; Hosdey, C.; Davoli, M. A.; Hendrickson, A.; Hao, K.; GIROS, B.; Alonge, K. M.; Mechawar, N.

10.1101/2024.02.09.579711 — neuroscience — Posted on 2024-02-12

2854 Coordinated Immune Cell Networks in the Bone Marrow Microenvironment Define the Graft versus Leukemia Response with Adoptive Cellular Therapy

Maurer, K.; Park, C.; Mani, S.; Borji, M.; Penter, L.; Jin, Y.; Zhang, J. Y.; Shin, C.; Brenner, J. R.; Southard, J.; Krishna, S.; Lu, W.; Lyu, H.; Abbondanza, D.; Mangum, C.; Olsen, L. R.; Neuberg, D. S.; Bachireddy, P.; Farhi, S. L.; Li, S.; Livak, K. J.; Ritz, J.; Soiffer, R. J.; Wu, C. J.; Azizi, E.

10.1101/2024.02.09.579677 — cancer biology — Posted on 2024-02-12

2855 Novel murine closed-loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

Dias, I.; Kollarik, S.; Siegel, M.; Baumann, C. R.; Moreira, C. G.; Noain, D.

10.1101/2024.02.12.579922 — neuroscience — Posted on 2024-02-12

2856 The RNA demethylases ALKBH5 and FTO regulate translation of the ATF4 mRNA in sorafenib-treated hepatocarcinoma cells

Mazroui, R.; Adjibade, P.

10.1101/2024.02.09.577647 — cancer biology — Posted on 2024-02-12

2857 Cyclin-dependent kinase 5 (Cdk5) activity is modulated by light and gates rapid phase shifts of the circadian clock

Brenna, A.; Borsa, M.; Saro, G.; Ripperger, J. A.; Glauser, D. A.; Yang, Z.; Adamantidis, A.; Albrecht, U.

10.1101/2024.02.08.579499 — neuroscience — Posted on 2024-02-12

2858 Medulloblastoma oncogene aberrations are not involved in tumor initiation, but essential for disease progression and therapy resistance

Okonechnikov, K.; Joshi, P.; Koerber, V.; Rademacher, A.; Bortolomeazzi, M.; Mallm, J.-P.; da Silva, P. B. G.; Statz, B.; Sepp, M.; Sarropoulos, I.; Yamada-Saito, T.; Vaillant, J.; Wittmann, A.; Schramm, K.; Blattner-Johnson, M.; Fiesel, P.; Jones, B.; Milde, T.; Pajtler, K.; van Tilburg, C. M.; Witt, O.; Bochennek, K.; Weber, K. J.; Nonnenmacher, L.; Reimann, C.; Schueller, U.; Mynarek, M.; Rutkowski, S.; Jones, D. T. W.; Korshunov, A.; Rippe, K.; Westermann, F.; Thongjuea, S.; Hoefer, T.; Kaessmann, H.; Kutscher, L. M.; Pfister, S. M.

10.1101/2024.02.09.579690 — cancer biology — Posted on 2024-02-12

2859 Spatiotemporal regulation of the hepatocyte growth factor receptor MET activity by sorting nexins 1 and 2 in HCT116 colorectal cancer cells

Garcia Delgado, L.; Derome, A.; Longpre, S.; Giroux-Dansereau, M.; Basbous, G.; Lavoie, C. L.; Saucier, C.; Denault, J.-B.

10.1101/2024.02.10.579658 — cancer biology — Posted on 2024-02-12

2860 In Silico designed cell-penetrating anti-cancer peptide specifically inhibits VEGF-A expression

Banerjee, N.; Roy, L.; Panda, S.; Roychowdhury, T.; Chatterjee, S.

10.1101/2024.02.08.579410 — biophysics — Posted on 2024-02-12

2861 Multimodal illumination platform for 3D single-molecule super-resolution imaging throughout mammalian cells

Nelson, T.; Vargas-Hernandez, S.; Freire, M.; Cheng, S.; Gustavsson, A.-K.

10.1101/2024.02.08.579549 — biophysics — Posted on 2024-02-12

2862 Binding Position Dependent Modulation of Smoothened Activity by Cyclopamine

Kim, K.; Bansal, P. D.; Shukla, D.

10.1101/2024.02.08.579369 — biophysics — Posted on 2024-02-12

2863 Biocompatible Neodymium-Doped Nanocrystals as Probes for Diffraction-limited, in vitro Temperature Sensing

Bravo, M.; Yang, S.; Brooke, S.; Wen, D.; Taemaitree, F.; Zaman, S.; Uji-i, H.; Rocha, S.; Mulvaney, P.; Hutchison, J. A.

10.1101/2024.02.08.579538 — biophysics — Posted on 2024-02-12

2864 Nanoscale interaction of endonuclease APE-1 with DNA characterized by atomic force microscopy

Vemulapalli, S.; Hashemi, M.; Chen, Y.; Pramanik, S.; Bhakat, K. K.; Lyubchenko, Y. L.

10.1101/2024.02.11.579811 — biophysics — Posted on 2024-02-12

2865 Biochemical, biophysical, and structural investigations of two mutants (C154Y and R312H) of the human Kir2.1 channel involved in the Andersen-Tawil syndrome.

Zuniga, D.; Zoumpoulakis, A.; Veloso, R. F.; Peverini, L.; Shi, S.; Pozza, A.; Kugler, V.; Bonnete, F.; Bouceba, T.; Wagner, R.; Corringer, P.-J.; Fernandes, C. A.; Venien-Bryan, C.

10.1101/2024.02.09.579451 — biophysics — Posted on 2024-02-12

2866 Determination of Absolute Intramolecular Distances in Proteins by Anomalous X-ray Scattering Interferometry

Stubhan, S.; Baptist, A. V.; Korosy, C.; Narducci, A.; Moya Munoz, G. G.; Wendler, N.; Lak, A.; Sztucki, M.; Cordes, T.; Lipfert, J.

10.1101/2024.02.09.579681 — biophysics — Posted on 2024-02-12

2867 Myosin-I Synergizes with Arp2/3 Complex to Enhance Pushing Forces of Branched Actin Networks

Xu, M.; Rutkowski, D. M.; Rebowski, G.; Boczkowska, M.; Pollard, L. W.; Dominguez, R.; Vavylonis, D.; Ostap, E. M.

10.1101/2024.02.09.579714 — biophysics — Posted on 2024-02-12

2868 A proteome-wide quantitative guide for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.

10.1101/2024.02.10.579775 — biophysics — Posted on 2024-02-12

2869 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles

Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.

10.1101/2024.02.07.578591 — biophysics — Posted on 2024-02-12

2870 Generative artificial intelligence performs rudimentary structural biology modelling

Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.

10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-02-12

2871 Contrastive Fitness Learning: Reprogramming Protein Language Models for Low-N Learning of Protein Fitness Landscape

Zhao, J.; Zhang, C.; Luo, Y.

10.1101/2024.02.11.579859 — bioinformatics — Posted on 2024-02-12

2872 Cell circuits underlying nanomaterial specific respiratory toxicology

Voss, C.; Han, L.; Ansari, M.; Strunz, M.; Haefner, V.; Ballester-Lopez, C.; Angelidis, I.; Mayr, C. H.; Berthing, T.; Conlon, T.; Liu, Q.; Ren, H.; Zhou, Q.; Schmid, O.; Yildirim, A. O.; Rehberg, M.; Vogel, U.; Gothe-Schniering, J.; Theis, F. J.; Schiller, H. B.; Stoeger, T.

10.1101/2024.02.10.579746 — pharmacology and toxicology — Posted on 2024-02-12

2873 Classification of LTR Retrotransposons via Interaction Prediction

Cardoso, S. C. S.; Domingues, D. S.; Paschoal, A. R.; Fischer, C. N.; Cerri, R.

10.1101/2024.02.11.579858 — bioinformatics — Posted on 2024-02-12

2874 traits.build: a data model, workflow and R package for building harmonised ecological trait databases

Wenk, E.; Bal, P.; Coleman, D.; Gallagher, R. V.; Yang, S.; Falster, D. S.

10.1101/2024.02.11.579848 — bioinformatics — Posted on 2024-02-12

2875 Genome-wide Nucleosome Positioning and Associated Features uncovered with Interpretable Deep Residual Networks

Masoudi-Sobhanzadeh, Y.; Li, S.; Peng, Y.; R Panchenko, A.

10.1101/2024.02.09.579668 — bioinformatics — Posted on 2024-02-12

2876 Cell state transition analysis reveals a causal network that controls critical limb ischemia

Rukhlenko, O. S.; McClung, J. M.; Tuliakova, A.; Annex, B. H.; Kholodenko, B. N.

10.1101/2024.02.09.579659 — bioinformatics — Posted on 2024-02-12

2877 Identification Drug Targets for Oxaliplatin-Induced Cardiotoxicity without affecting cancer treatment through Inter Variability Cross-Correlation Analysis (IVCCA)

Du, J.; Sudlow, L. C.; Biswas, H.; Mitchell, J. D.; Mollah, S.; Berezin, M. Y.

10.1101/2024.02.11.579390 — bioinformatics — Posted on 2024-02-12

2878 Scalable nonparametric clustering with unified marker gene selection for single-cell RNA-seq data

Nwizu, C.; Hughes, M.; Ramseier, M. L.; Navia, A.; Shalek, A. K.; Fusi, N.; Raghavan, S.; Winter, P. S.; Amini, A. P.; Crawford, L.

10.1101/2024.02.11.579839 — bioinformatics — Posted on 2024-02-12

2879 Processing-bias correction with DEBIAS-M improves cross-study generalization of microbiome-based prediction models

Austin, G. I.; Brown Kav, A.; Park, H.; Biermann, J.; Uhlemann, A.-C.; Korem, T.

10.1101/2024.02.09.579716 — bioinformatics — Posted on 2024-02-12

2880 Scaffold-Lab: Critical Evaluation and Ranking of Protein Backbone Generation Methods in A Unified Framework

Zheng, Z.; Zhang, B.; Zhong, B.; Liu, K.; Yu, J.; Li, Z.; Zhu, J.; Wei, T.; Chen, H.-F.

10.1101/2024.02.10.579743 — bioinformatics — Posted on 2024-02-12

2881 SomaScan Bioinformatics: Normalization, Quality Control, and Assessment of Pre-Analytical Variation

Candia, J.

10.1101/2024.02.09.579724 — bioinformatics — Posted on 2024-02-12

2882 A Predictive Model: The Key to Success for Badminton Servers and Receivers

super, c.

10.1101/2024.02.10.579788 — bioinformatics — Posted on 2024-02-12

2883 Cellpose3: one-click image restoration for improved cellular segmentation

Stringer, C.; Pachitariu, M.

10.1101/2024.02.10.579780 — bioinformatics — Posted on 2024-02-12

2884 Proteus: pioneering protein structure generation for enhanced designability and efficiency

Wang, C.; Qu, Y.; Peng, Z.; Wang, Y.; Zhu, H.; Chen, D.; Cao, L.

10.1101/2024.02.10.579791 — bioinformatics — Posted on 2024-02-12

2885 Discovery of Phenyl-β-D-glucuronide Medical Function for in Vivo Producing Handheld Gas Sensor Detectable Phenol-like Breath Marker: The Future of Induced Volatolomics in Cancer Risk Pre-warning

Xue, C. L.; Yan, Y. F.; Ni, H. Y.; Yi, H. C.; Xu, Y. L.; Xiang, S. Y.; Wu, Y. J.; Jin, H.; Cui, D. x.

10.1101/2024.02.09.579735 — bioengineering — Posted on 2024-02-12

2886 Thermostability and binding properties of single-chained Fv fragments derived from therapeutic antibodies

Tadokoro, T.; Tsuboi, H.; Nakamura, K.; Hayakawa, T.; Ohmura, R.; Kato, I.; Inoue, M.; Tsunoda, S.-i.; Niizuma, S.; Okada, Y.; Otsuguro, S.; Maenaka, K.

10.1101/2024.02.09.577534 — bioengineering — Posted on 2024-02-12

2887 HiCrayon reveals distinct layers of multi-state 3D chromatin organization

Nolan, B.; Harris, H. L.; Kalluchi, A.; Reznicek, T. E.; Cummings, C. T.; Rowley, M. J.

10.1101/2024.02.11.579821 — genomics — Posted on 2024-02-12

2888 Differential Conservation and Loss of CR1 Retrotransposons in Squamates Reveals Lineage-Specific Genome Dynamics across Reptiles

Gable, S. M.; Bushroe, N. A.; Mendez, J. M.; Wilson, A. A.; Pinto, B. J.; Gamble, T.; Tollis, M.

10.1101/2024.02.09.579686 — genomics — Posted on 2024-02-12

2889 The contribution of movement to social network structure and spreading dynamics under simple and complex transmission

Chimento, M.; Farine, D. R.

10.1101/2024.02.09.579705 — animal behavior and cognition — Posted on 2024-02-12

2890 Whole-Genome Sequencing of Three Extremophile Bacillus subtilis StrainsIsolated from the Atacama Desert

Cavanaugh, N. T.; Kumar, G.; Couto Frignani, M.; Thewedros, N.; Twahirwa, M.; Riquelme, C.; Hudson, A.; Chai, Y.; Godoy, V.

10.1101/2024.02.11.578748 — genomics — Posted on 2024-02-12

2891 Rules of departure: Antiphony and personalized vocal spaces in wild male elephant group coordination

Rantsiou, E.; Pignatelli, A.

10.1101/2024.02.07.579388 — animal behavior and cognition — Posted on 2024-02-12

2892 Critical Differential Expression Assessment for Individual Bulk RNA-Seq Projects

Warden, C. D.; Wu, X.

10.1101/2024.02.10.579728 — genomics — Posted on 2024-02-12

2893 Tropical and montane A. cerana show distinct dance-distance calibration curves

A K, B. K.; George, E. A.; Brockmann, A.

10.1101/2024.02.10.579752 — animal behavior and cognition — Posted on 2024-02-12

2894 State-dependent dynamics of cuttlefish mantle activity

Cohen Bodenes, S.; Neri, P.

10.1101/2023.06.19.545578 — animal behavior and cognition — Posted on 2024-02-12

2895 Insights from Genetic Studies: SNP Analyses Confirm White Clover Naturalization in Brazil

de Alencar, A. S.; Suyama, Y.; Takahashi, D.; Mansano, V. d. F.; Lira, C. d. F.

10.1101/2024.02.09.579627 — genetics — Posted on 2024-02-12

2896 The ivory lncRNA regulates seasonal color patterns in buckeye butterflies

Fandino, R. A.; Brady, N. K.; Chatterjee, M.; McDonald, J. M. C.; Livraghi, L.; van der burg, K.; Mazo-Vargas, A.; Reed, R. D.

10.1101/2024.02.09.579733 — genetics — Posted on 2024-02-12

2897 Cytotoxicity and resistance evolution of a novel antifungal carbon nanoparticle

Poudel Sharma, S.; Paudyal, S.; Domena, J.; Zhou, Y.; Cleven, E. C.; Agatemor, C.; Van Dyken, J. D.; Leblanc, R. M.

10.1101/2024.02.11.579833 — evolutionary biology — Posted on 2024-02-12

2898 A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

Livraghi, L.; Hanly, J. J.; Evans, E.; Wright, C. J.; Loh, L. S.; Mazo-Vargas, A.; Kamrava, K.; Carter, A. T.; van der Heijden, E. S.; Reed, R. D.; Papa, R.; Jiggins, C. D.; Martin, A.

10.1101/2024.02.09.579710 — evolutionary biology — Posted on 2024-02-12

2899 Bats of a feather: Range characteristics and wing morphology predict phylogeographic breaks in volant vertebrates

Decker, S. K.; Provost, K. L.; Carstens, B. C.

10.1101/2024.02.11.579809 — evolutionary biology — Posted on 2024-02-12

2900 Forecasting of phenotypic and genetic outcomes of experimental evolution in Pseudomonas syringae and Pseudomonas savastanoi

Pentz, J. T.; Biswas, A.; Alsaed, B.; Lind, P. A.

10.1101/2024.02.10.579745 — evolutionary biology — Posted on 2024-02-12

2901 An increasing Arctic-Boreal CO2 sink despite strong regional sources

Virkkala, A.-M.

10.1101/2024.02.09.579581 — ecology — Posted on 2024-02-12

2902 Microbial responses to stress cryptically alter natural selection on plants

Bolin, L. G.; Lau, J. A.

10.1101/2024.02.09.579697 — ecology — Posted on 2024-02-12

2903 Modeling the microbiome of Utah's Great Salt Lake: A regression analysis of key abiotic factors impacting growth of Dunaliella green algae in the GSL's South Arm

Fontana, C. G.; Maybruck, V. G.; Billings, R. M.; Mansfeldt, C.; Trower, E. J.

10.1101/2024.02.10.579688 — ecology — Posted on 2024-02-12

2904 Developmental pathways underlying sexual differentiation in a U/V sex chromosome system

Liesner, D.; Cossard, G.; Zheng, M.; Godfroy, O.; Barrera-Redondo, J.; Haas, F. B.; Coelho, S. M.

10.1101/2024.02.09.579736 — developmental biology — Posted on 2024-02-12

2905 Microtubule forces drive nuclear damage in LMNA cardiomyopathy

Amiad Pavlov, D.; Corredera, C. S.; Dehghany, M.; Heffler, J.; Shen, K. M.; Zuela - Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.

10.1101/2024.02.10.579774 — cell biology — Posted on 2024-02-12

2906 MDM2 acts as a timer reporting the length of mitosis

Fulcher, L.; Sobajima, T.; Gibbs-Seymour, I.; Barr, F. A.

10.1101/2023.05.26.542398 — cell biology — Posted on 2024-02-12

2907 Unleashing precision and freedom of optical manipulation: Software-aided real-time precision opto-control of intracellular molecular activities and cell functions

Dong, B.; Everly, R. M.; Mahapatra, S.; Carlsen, M. S.; Ma, S.; Zhang, C.

10.1101/2024.02.09.579709 — cell biology — Posted on 2024-02-12

2908 The Cas10 nuclease activity relieves host dormancy to facilitate spacer acquisition and retention during type III-A CRISPR immunity

Aviram, N.; Shilton, A.; Lyn, N.; Reis, B. S.; Brivanlou, A.; Marraffini, L. A.

10.1101/2024.02.11.579731 — microbiology — Posted on 2024-02-12

2909 TL1A/DR3 signaling regulates the generation of pathogenic Th9 cells in experimental inflammatory bowel disease

Menghini, P.; Butto, L.; Gomez-Nguyen, A.; Aladyshkina, N.; Buela, K.-A.; Osme, A.; Chan, R.; Bamias, G.; Pizarro, T. T.; Cominelli, F.

10.1101/2024.02.09.579684 — immunology — Posted on 2024-02-12

2910 Benchmark of cellular deconvolution methods using a multi-assay reference dataset from postmortem human prefrontal cortex

Huuki-Myers, L. A.; Montgomery, K. D.; Kwon, S. H.; Cinquemani, S.; Maden, S. K.; Eagles, N. J.; Kleinman, J. E.; Hyde, T. M.; Hicks, S. C.; Maynard, K. R.; Collado-Torres, L.

10.1101/2024.02.09.579665 — neuroscience — Posted on 2024-02-12

2911 Alterations in Lysosomal, Glial and Neurodegenerative Biomarkers in Patients with Sporadic and Genetic Forms of Frontotemporal Dementia

Hsiao-Nakamoto, J.; Chiu, C.-L.; VandeVrede, L.; Ravi, R.; Vandenberg, B.; De Groot, J.; Tsogtbaatar, B.; Fang, M.; Auger, P.; Gould, N. S.; Marchioni, F.; Powers, C. A.; Davis, S. S.; Suh, J. H.; Alkabsh, J.; Heuer, H. W.; Lago, A. L.; Scearce-Levie, K.; Seeley, W. W.; Boeve, B. F.; Rosen, H. J.; Berger, A.; Tsai, R.; Di Paolo, G.; Boxer, A. L.; Bhalla, A.; Huang, F.

10.1101/2024.02.09.579529 — neuroscience — Posted on 2024-02-12

2912 Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease.

Alcantara-Gonzalez, D.; Kennedy, M.; Criscuolo, C.; Botterill, J. J.; Scharfman, H.

10.1101/2024.02.09.579729 — neuroscience — Posted on 2024-02-12

2913 Mind the blank: behavioral, experiential, and physiological signatures of absent-mindedness

Musat, E. M.; Corcoran, A. W.; Belloli, L.; Naccache, L.; Andrillon, T.

10.1101/2024.02.11.579845 — neuroscience — Posted on 2024-02-12

2914 Impaired 26S proteasome causes leaning and memory deficiency and induces neuroinflammation mediated by NF-kappaB in mice

Huber, C.; Callegari, E.; Paez, D.; Li, X.; Wang, H.

10.1101/2024.02.09.579699 — neuroscience — Posted on 2024-02-12

2915 Closed-loop electrical stimulation to prevent focal epilepsy progression and long-term memory impairment

Ferrero, J. J.; Hassan, A. R.; Yu, Z.; Zhao, Z.; Ma, L.; Wu, C.; Shao, S.; Kawano, T.; Engel, J.; Doyle, W.; Devinsky, O.; Khodagholy, D.; Gelinas, J. N.

10.1101/2024.02.09.579660 — neuroscience — Posted on 2024-02-12

2916 Tetrapod terrestrialisation: a weight-bearing potential already present in the humerus of the stem-tetrapod fish Eusthenopteron foordi

Clarac, F.; Cornille, A.; Bijl, S.; Sanchez, S.

10.1101/2024.02.09.579723 — paleontology — Posted on 2024-02-12

2917 Computational hemodynamic indices to identify Transcatheter Aortic Valve Implantation degeneration

Crugnola, L.; Vergara, C.; Fusini, L.; Fumagalli, I.; Luraghi, G.; Redaelli, A.; Pontone, G.

10.1101/2024.02.09.579647 — bioengineering — Posted on 2024-02-12

2918 Mathematical Modelling Indicates Th-cell Targeted Antibody-Dependent Cellular Cytotoxic Is a Crucial Obstacle Hurdling HIV Vaccine Development

Xu, Z.; Zeng, Q.; Yang, D.; Sun, X.; Wei, D.; Demongeot, J.; Cao, Z.

10.1101/2024.02.07.579394 — immunology — Posted on 2024-02-12

2919 Automated multimodal imaging of Caenorhabditis elegans behavior in multi-well plates

Ji, H.; Chen, D.; Fang-Yen, C.

10.1101/2024.02.09.579675 — neuroscience — Posted on 2024-02-12

2920 Brain activation during the N-back working memory task in individuals with spinal cord injury: a functional near-infrared spectroscopy study

Chen, D. Y.; Di, X.; Amaya, N.; Sun, H.; Pal, S.; Biswal, B.

10.1101/2024.02.09.579655 — neuroscience — Posted on 2024-02-12

2921 Related PP2C phosphatases Pic3 and Pic12 negatively regulate immunity in tomato to Pseudomonas syringae

Xia, F.; Zhang, N.; Smith, R. E.; Chakraborty, J.; Sobol, G.; Tang, X.; Fei, Z.; Sessa, G.; Martin, G. B.

10.1101/2024.02.08.579555 — plant biology — Posted on 2024-02-12

2922 Molecular attributes of the tropical tree Avicennia schaueriana involved in the response and tolerance to low temperatures

Moura, Y. A.; Aono, A. H.; Cruz, M. V.; Alves-Pereira, A.; Vidal, J. d. D.; de Souza, A. P.

10.1101/2024.02.08.579386 — plant biology — Posted on 2024-02-12

2923 Carbon nanoparticle exposure strengthens water-relation parameters by stimulating abscisic acid pathway and aquaporins genes in rice

Kumar, A.; Manasa S, L.; Kashyap, J.; Mandal, S.; Mishra, G.; Rath, J.; Rout, G. R.; Panigrahi, K. C.; Panigrahy, M.

10.1101/2024.02.11.579789 — plant biology — Posted on 2024-02-12

2924 Whole-Plant Physiological Identification and Quantification of Disease Progression

Friedman, S.; Dalal, A.; Batat, D.; Burdman, S.; Sela, Y.; Hipsch, M.; Rosenwaser, S.; Marcos Hadad, E.; Covo, S.; Moshelion, M.

10.1101/2024.02.11.579801 — plant biology — Posted on 2024-02-12

2925 MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn's disease

Layunta, E.; Javerfelt, S.; van de Koolwijk, F. C.; Sivertsson, M.; Dolan, B.; Arike, L.; Thulin, S.; Vallance, B. A.; Pelaseyed, T.

10.1101/2024.02.08.578867 — physiology — Posted on 2024-02-12

2926 Augmented-reality-based exercise increases salivary oxytocin

Shima, T.; Iijima, J.; Sutoh, H.; Terashima, C.; Matsuura, Y.

10.1101/2024.02.08.579578 — physiology — Posted on 2024-02-12

2927 Impaired transitioning of the FXR ligand binding domain to an active state underlies a PFIC5 phenotype

Behrendt, A.; Stindt, J.; Pfister, E.-D.; Grau, K.; Brands, S.; Bastianelli, A.; Droege, C.; Stalke, A.; Bonus, M.; Sgodda, M.; Cantz, T.; Franke, S.; Baumann, U.; Keitel, V.; Gohlke, H.

10.1101/2024.02.08.579530 — physiology — Posted on 2024-02-12

2928 NCLX controls hepatic mitochondrial Ca2+ extrusion and couples hormone-mediated mitochondrial Ca2+ oscillations with gluconeogenesis

Taha, M.; Assali, E. A.; Stutzmann, G. E.; Shirihai, O. S.; Hershfinkel, M.; Sekler, I.

10.1101/2024.02.09.579606 — physiology — Posted on 2024-02-12

2929 Comparative analysis of Formyl peptide receptor 1 and Formyl peptide receptor 2 reveals shared and preserved signaling profiles

Rescher, U.; Raabe, C. A.; Pajonczyk, D.; Sternschulte, M. F.; Bermudez, M.; Soehnlein, O.

10.1101/2024.02.08.579483 — pharmacology and toxicology — Posted on 2024-02-12

2930 Dermatological plants and their uses in the Receptarium of Burkhard III from Hallwyl from 16th century Switzerland: Data mining a historical text and preliminary in vitro screening

Stehlin, J.; Albert, I.; Frei, T.; Frei Haller, B.; Lardos, A.

10.1101/2024.02.09.579674 — pharmacology and toxicology — Posted on 2024-02-12

2931 NRP1-expressing myeloid cells promote arteriogenesis in the ischemic limb

Cho, J. S.; Patel, A. S.; Fantin, A.; Ludwinski, F. E.; Pichette, C.; Rudnicki, M.; Denti, L.; Mondragon, A.; Saha, P.; Smith, A.; Ruhrberg, C.; Moderai, B.

10.1101/2024.02.11.579823 — pathology — Posted on 2024-02-12

2932 PuMA: PubMed Gene-Celltype-Relation Atlas

Bickmann, L.; Sandmann, S.; Walter, C.; Varghese, J.

10.1101/2024.02.09.579584 — bioinformatics — Posted on 2024-02-12

2933 Graph-based Nanopore Adaptive Sampling with GNASTy enables sensitive pneumococcal serotyping in complex samples

Horsfield, S. T.; Fok, B.; Fu, Y.; Turner, P.; Lees, J. A.; Croucher, N. J.

10.1101/2024.02.11.579857 — genomics — Posted on 2024-02-12

2934 Whole-Genome Sequencing of a Janthinobacterium sp. Isolated from the Patagonian Desert

Cavanaugh, N. T.; Kumar, G.; Reverdy Pearson, A.; Colbert, J.; Riquelme, C.; Hudson, A. O.; Chai, Y.; Godoy, V.

10.1101/2024.02.11.579814 — genomics — Posted on 2024-02-12

2935 The genome of Pasteuria ramosa reveals a high turnover rate of collagen-like genes

Thivolle, A.; Paljakka, M.; Ebert, D.; Fields, P. D.

10.1101/2024.02.09.579640 — genomics — Posted on 2024-02-12

2936 BPTF cooperates with MYCN and MYC to link neuroblastoma cell cycle control to epigenetic cellular states

Felipe, I.; Martinez de Villarreal, J.; Patel, K.; Martinez-Torrecuadrada, J. L.; Grossmann, L. D.; Roncador, G.; Cubells, M.; Farrel, A.; Nathan, K.; Sabroso-Lasa, S.; Sancho-Trevino, L.; Torres, K.; Martinez, D.; Munoz-Peralta, J.; Garcia, F.; Pogoriler, J.; Moreno, L.; Maris, J.; Real, F. X.

10.1101/2024.02.11.579816 — genomics — Posted on 2024-02-12

2937 Genetic regulation of injury induced heterotopic ossification in adult zebrafish

Kaliya-Perumal, A.-K.; Celik, C.; Carney, T. J.; Harris, M. P.; Ingham, P. W.

10.1101/2024.02.09.579618 — genetics — Posted on 2024-02-12

2938 DNA barcoding affirms the presence of invasive Parachanna obscura and new records of some species in the Mweru-Luapula fishery

Seemani, B.; Oosthuizen, C.; Bloomer, P.; Katongo, C.; Klopper, A.

10.1101/2024.02.11.579834 — genetics — Posted on 2024-02-12

2939 MR-SPLIT: a novel method to address selection and weak instrument bias in one-sample Mendelian randomization studies

Shi, R.; Wang, L.; Burgess, S.; Cui, Y.

10.1101/2024.02.11.579683 — genetics — Posted on 2024-02-12

2940 How to validate a Bayesian evolutionary model

Mendes, F. K.; Bouckaert, R.; Carvalho, L. M.; Drummond, A. J.

10.1101/2024.02.11.579856 — evolutionary biology — Posted on 2024-02-12

2941 Pushing the limits: expanding the temperature tolerance of a coral photosymbiont through differing selection regimes

Scharfenstein, H. J.; Peplow, L. M.; Alvarez-Roa, C.; Nitschke, M.; Buerger, P.; Chan, W. Y.; van Oppen, M. J. H.

10.1101/2024.02.11.579409 — evolutionary biology — Posted on 2024-02-12

2942 Predicting gene sequences with AI to study evolutionarily selected codon usage patterns

Sidi, T.; Bahiri Elitzur, S.; Tuller, T.; Kolodny, R.

10.1101/2024.02.11.579798 — evolutionary biology — Posted on 2024-02-12

2943 What unexplored means: Mapping undersampled regions in natural history collections

Chakrabarty, P.; Ball, L.; Bedoya, A.; Rodriguez Machado, S.; Paredes-Burneo, D.; Rutledge, S.; Boyd, D.; Vander Pluym, D.; Babb-Biernacki, S.; Chipps, A.; Ozturk, R.; Terzi, Y.

10.1101/2024.02.09.579602 — ecology — Posted on 2024-02-12

2944 Hemilineage-specific expression of the RHG genes Grim and Reaper sculpt neural network composition during Drosophila neurogenesis

Sproston, C. J.; Rak, J. E.; Kondo, S.; Williams, D. W.

10.1101/2024.02.11.579841 — developmental biology — Posted on 2024-02-12

2945 Oncogenic STIL-mediated loss of BRCA1 functionality causes DNA damage and centrosome amplification

Sanghi, S.; Singh, P.

10.1101/2024.02.11.579865 — cell biology — Posted on 2024-02-12

2946 SLC-25A46 Regulates Mitochondrial Fusion through FZO-1/Mitofusin and is Essential for Maintaining Neuronal Morphology

Obinata, H.; Takahashi, H.; Shimo, S.; Oda, T.; Sugimoto, A.; Niwa, S.

10.1101/2024.02.11.579862 — cell biology — Posted on 2024-02-12

2947 DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes

Lorzadeh, A.; Ye, G.; Sharma, S.; Jadhav, U.

10.1101/2024.02.11.579850 — molecular biology — Posted on 2024-02-12

2948 Prevalence and Associated Risk Factors of Bovine Trypanosomosis in Diga District, Western Ethiopia

Gessese, A. T.; Yadesa, G.

10.1101/2024.02.11.579830 — microbiology — Posted on 2024-02-12

2949 NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell Activation

Forsyth, K. S.; Toothacre, N. E.; Jiwarjka, N.; Driscoll, A. M.; Shallberg, L. A.; Cunningham-Rundles, C.; Barmettler, S.; Farmer, J. R.; Verbsky, J.; Routes, J.; Beiting, D. P.; Romberg, N.; May, M. J.; Anguera, M.

10.1101/2024.02.08.579505 — immunology — Posted on 2024-02-12

2950 Regulation of IFNgamma production by ZFP36L2 in T cells is context-dependent

Zandhuis, N. D.; Guislain, A.; Popalzij, A.; Engels, S.; Popovic, B.; Turner, M.; Wolkers, M. C.

10.1101/2024.02.09.579641 — immunology — Posted on 2024-02-12

2951 Spatial transcriptomics reveals focal induction of molecular responses and cellular interactions in the small intestine during Heligmosomoides polygyrus infection.

Campillo Poveda, M.; Laidlaw, R. F.; Hardy, O.; Otto, T. D.; Maizels, R. M.

10.1101/2024.02.09.579622 — immunology — Posted on 2024-02-12

2952 Asymmetric representation of symmetric semantic information in the human brain

Wang, J.; Kawahata, K.; Blanc, A.; Maeda, N.; Nishimoto, S.; Nishida, S.

10.1101/2024.02.09.579613 — neuroscience — Posted on 2024-02-12

2953 Impaired drainage through capillary-venous networks contributes to age-related white matter loss

Stamenkovic, S.; Schmid, F.; Weitermann, N.; Takasaki, K. T.; Bonney, S. K.; Sosa, M. J.; Li, Y.; Bennett, H. C.; Kim, Y.; Waters, J.; Shih, A.

10.1101/2024.02.11.579849 — neuroscience — Posted on 2024-02-12

2954 How long is long? Word length effects in reading correspond to minimal graphemic units: An MEG study in Bangla

Moitra, S.; Chacon, D. A.; Stockall, L.

10.1101/2023.10.04.560854 — neuroscience — Posted on 2024-02-12

2955 Dose escalation pre-clinical trial of novel Dok7-AAV in mouse model of DOK7 congenital myasthenia

Cossins, J. A.; Kozma, I.; Canzonetta, C.; Hawkins, A.; Beeson, D.; Sepulveda, P.; Dong, Y.

10.1101/2024.02.09.579626 — neuroscience — Posted on 2024-02-12

2956 Therapeutic potential of glabridin and gymnemic acid alleviates eye choroidal thickness and neovascularization in diabetic model rats

Khimmaktong, W.; Komolkriengkrai, M.; Matsathit, U.

10.1101/2024.02.08.579467 — pathology — Posted on 2024-02-12

2957 Biomechanical Implications of Spinopelvic Alignment on Femoral Head Cartilage and the Proximal Femoral Physis in Slipped Capital Femoral Epiphysis: A Theoretical Finite Element Analysis

Kumaran, Y.; Mumtaz, M.; Quatman, C.; Balch-Samora, J.; Soehnlen, S.; Hoffman, B.; Tripathi, S.; Nishida, N.; Goel, V. K.

10.1101/2024.02.08.579521 — bioengineering — Posted on 2024-02-12

2958 Expression of Most Retrotransposons in Human Blood Correlates with Biological Aging

Tsai, Y.-T.; Seymen, N.; Thompson, I. R.; Zou, X.; Mumtaz, W.; Gerlevik, S.; Mufti, G. J.; Karimi, M. M.

10.1101/2024.02.09.579582 — genomics — Posted on 2024-02-12

2959 Polygenic architecture of adaptation to a high-altitude environment for Drosophila melanogaster wing shape and size.

Pelletier, K.; Bilodeau, M.; Pellizzari-Delano, I.; Siemon, M. D.; Huang, Y.; Pool, J. E.; Dworkin, I. E.

10.1101/2024.02.08.579525 — evolutionary biology — Posted on 2024-02-12

2960 Group composition and dynamics in American Crows: insights into an unusual cooperative breeder

Caffrey, C.; Peterson, C. C.

10.1101/2024.02.01.578454 — ecology — Posted on 2024-02-12

2961 UXS1 regulates UDP-GlcA levels to support growth of UGDH-high cancer cells

Wang, Y.; Zhou, C.; Bou-Tayeh, B.; Lisle, R.; Kriaucionis, S.; Shi, Y.

10.1101/2024.02.08.579288 — cell biology — Posted on 2024-02-12

2962 WITHDRAWN: Mapping miRNA regulation of MGAT3 reveals upregulation as the dominant mode of action

Zohora, F. T.; Batu, T. T.; Mahal, L. K.

10.1101/2023.08.24.554695 — molecular biology — Posted on 2024-02-12

2963 A Single-shot ChAd3 Vaccine Provides Protection from Intramuscular and Aerosol Sudan Virus Exposure

Honko, A. N.; Hunegnaw, R.; Moliva, J. I.; Ploquin, A.; Dulan, C. N. M.; Murray, T.; Carr, D.; Foulds, K. E.; Geisbert, J. B.; Geisbert, T. W.; Johnson, J. C.; Wollen-Roberts, S. E.; Trefry, J. C.; Stanley, D. A.; Sullivan, N. J.

10.1101/2024.02.07.579118 — immunology — Posted on 2024-02-12

2964 Network pharmacology of xylazine to understand its health consequences and develop mechanistic based remediations.

Kumar, A. H.

10.1101/2024.02.08.579475 — pharmacology and toxicology — Posted on 2024-02-12

2965 ANDROMEDA by Prosilico and log D outperform human hepatocytes for the prediction of intrinsic hepatic metabolic clearance of carboxylic acids

Fagerholm, U.

10.1101/2023.12.04.569912 — pharmacology and toxicology — Posted on 2024-02-12

2966 Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes

Drotar, D.; Mojica-Avila, A. K.; Bloss, D. T.; Cohrs, C. M.; Manson, C. T.; Posgai, A. L.; Williams, M. D.; Brusko, M. A.; Phelps, E. A.; Wasserfall, C. H.; Speier, S.; Atkinson, M. A.

10.1101/2024.02.08.579175 — pathology — Posted on 2024-02-12

2967 Data-driven recombination detection in viral genomes

Alfonsi, T.; Bernasconi, A.; Chiara, M.; Ceri, S.

10.1101/2023.06.05.543733 — bioinformatics — Posted on 2024-02-12

2968 Automated 3D Landmarking of the Skull: A Novel Approach for Craniofacial Analysis

Wilke, F.; Matthews, H.; Herrick, N.; Dopkins, N.; Claes, P.; Walsh, S.

10.1101/2024.02.09.579642 — bioinformatics — Posted on 2024-02-12

2969 A Composite Biomarker Signature of Type 1 Diabetes Risk Identified via Augmentation of Parallel Multi-Omics Data from a Small Cohort

Alcazar, O.; Chuang, S.-T.; Ren, G.; Ogihara, M.; Webb-Robertson, B.-J. M.; Nakayasu, E. S.; Buchwald, P.; Abdulreda, M. H.

10.1101/2024.02.09.579673 — biochemistry — Posted on 2024-02-12

2970 Induction and in silico staging of human gastruloids with neural tube, segmented somites & advanced cell types

Hamazaki, N.; Yang, W.; Kubo, C.; Qiu, C.; Martin, B. K.; Garge, R. K.; Regalado, S. G.; Nichols, E.; Lee, C.; Daza, R. M.; Srivatsan, S.; Shendure, J.

10.1101/2024.02.10.579769 — developmental biology — Posted on 2024-02-12

2971 A screen of mutants generated and imaged by the International Mouse Phenotyping Consortium identifies 39 novel genes regulating the development of the secondary palate.

Bhaskar, A.; Astrof, S.

10.1101/2024.02.09.579685 — developmental biology — Posted on 2024-02-12

2972 Transcriptomic landscape of human induced pluripotent stem cell-derived osteogenic differentiation identifies a regulatory role of KLF16

Ru, Y.; Ma, M.; Zhou, X.; Kriti, D.; Cohen, N.; Souza, S.; Schaniel, C.; Motch Perrine, S. M.; Kuo, S.; Pinto, D.; Housman, G.; Wu, M.; Holmes, G.; Schadt, E.; van Bakel, H.; Zhang, B.; Jabs, E. W.

10.1101/2024.02.11.579844 — molecular biology — Posted on 2024-02-12

2973 PINK1 is a target of T cell responses in Parkinson's disease

Williams, G. P.; Michaelis, T.; Rodrigues Lima-Junior, J.; Frazier, A.; Tran, N. K.; Phillips, E. J.; Mallal, S. A.; Litvan, I.; Goldman, J. G.; Alcalay, R. N.; Sidney, J.; Sulzer, D.; Sette, A.; Lindestam Arlehamn, C. S.

10.1101/2024.02.09.579465 — immunology — Posted on 2024-02-12

2974 Functional dynamics and selectivity of two parallel corticocortical pathways from motor cortex to layer 5 circuits in somatosensory cortex

Kim, H.-H.; Bonekamp, K. E.; Gillie, G. R.; Autio, D. M.; Keller, T.; Crandall, S. R.

10.1101/2024.02.11.579810 — neuroscience — Posted on 2024-02-12

2975 Aligning with the predecessors and counterarguments: A systematic review of the anatomical correlates for the newly discovered meningeal layer in the existing literature

Kumar, A.; Kumar, R.; Narayan, R. K.; Nath, B.; Datusalia, A. K.; Rastogi, A. K.; Jha, R. K.; Kumar, P.; Pareek, V.; Prasoon, P.; Faiq, M. A.; Agrawal, P.; Prasad, S. N.; Kumari, C.; Asghar, A.

10.1101/2024.02.10.579742 — neuroscience — Posted on 2024-02-12

2976 Unifying approaches from statistical genetics and phylogenetics for mapping phenotypes in structured populations

Schraiber, J. G.; Edge, M. D.; Pennell, M.

10.1101/2024.02.10.579721 — genomics — Posted on 2024-02-12

2977 Liquid footprinting: A novel approach for DNA footprinting using short double-stranded cell-free DNA from plasma

Mueller, J.; Hartwig, C.; Mirko, S.; Lisa, B.; Christopher, A.; Yevhen, V.; Karolina, G.; Sebastian, D. O.; Thorsten, B.; Georg, W. F.; Arndt, v. H.; Kai, S.

10.1101/2024.02.09.579588 — genomics — Posted on 2024-02-12

2978 Global diversity and evolution of Salmonella Panama, an understudied serovar causing gastrointestinal and invasive disease worldwide: a genomic epidemiology study

Pulford, C. V.; Perez-Sepulveda, B. M.; Ingle, D. J.; Bengtsson, R. J.; Bennet, R. J.; Rodwell, E. V.; Pardos de la Gandara, M.; Chong, C.; De Silva, P. M.; Ravel, M.; Guibert, V.; Njamkepo, E.; Hall, N.; Chattaway, M. A.; Howden, B.; Williamson, D. A.; Hinton, J. C. D.; Weill, F.-X.; Baker, K. S.

10.1101/2024.02.09.579599 — genomics — Posted on 2024-02-12

2979 Identifying Ferroptosis Inducers, HDAC, and RTK Inhibitor Sensitivity in Melanoma Subtypes through Unbiased Drug Target Prediction

Pla, I.; Szabolcs, B. L.; Peter, P. N.; Ujfaludi, Z.; Kim, Y.; Horvatovich, P.; Sanchez, A.; Pawlowski, K.; Wieslander, E.; Guedes, J.; Pal, D. M.; Ascsillan, A. A.; Betancourt, L. H.; Nemeth, I. B.; Gil, J.; Almeida, N. P. d.; Szeitz, B.; Szadai, L.; Doma, V.; Woldmar, N.; Bartha, A.; Pahi, Z.; Pankotai, T.; Gyorffy, B.; Szasz, M. A.; Domont, G.; Nogueira, F.; Kwon, H. J.; Appelqvist, R.; Karpati, S.; Fenyo, D.; Malm, J.; Varga, G. M.; Kemeny, L. V.

10.1101/2024.02.08.579424 — cancer biology — Posted on 2024-02-12

2980 Constitutive activity of ionotropic glutamate receptors via hydrophobic substitutions in the ligand-binding domain

Seljeset, S.; Sintsova, O.; Wang, Y.; Harb, H. Y.; Lynagh, T.

10.1101/2023.08.03.551817 — biophysics — Posted on 2024-02-12

2981 Dynamic PRC1-CBX8 stabilizes a porous structure of chromatin condensates

Uckelmann, M.; Levina, V.; Taveneau, C.; Ng, X. H.; Pandey, V.; Martinez, J.; Mendiratta, S.; Houx, J.; Boudes, M.; Venugopal, H.; Trepout, S.; Zhang, Q.; Flanigan, S.; Li, M.; Sierecki, E.; Gambin, Y.; Das, P. P.; Bell, O.; de Marco, A.; Davidovich, C.

10.1101/2023.05.08.539931 — biophysics — Posted on 2024-02-12

2982 Miffi: Improving the accuracy of CNN-based cryo-EM micrograph filtering with fine-tuning and Fourier space information

Xu, D.; Ando, N.

10.1101/2023.12.08.570849 — biophysics — Posted on 2024-02-12

2983 Evaluating the Benefits and Limits of Multiple Displacement Amplification with Whole-Genome Oxford Nanopore Sequencing

Dadzie, F. A.; Beaudry, M. S.; Deyanov, A.; Slanis, H.; Duong, M. Q.; Turner, R.; Khan, A.; Arias, C. A.; Kissinger, J. C.; Glenn, T. C.; de Paula Baptista, R.

10.1101/2024.02.09.579537 — bioinformatics — Posted on 2024-02-12

2984 Investigating the performance of foundation models on human 3'UTR sequences

Vilov, S.; Heinig, M.

10.1101/2024.02.09.579631 — bioinformatics — Posted on 2024-02-12

2985 Federated Learning for Predicting Compound Mechanism of Action Based on Image-data from Cell Painting

Ju, L.; Hellander, A.; Spjuth, O.

10.1101/2024.02.09.579629 — bioinformatics — Posted on 2024-02-12

2986 Prediction of protein-carbohydrate binding sites from protein primary sequence

Nawar, Q. F.; Nafi, M. M. I.; Islam, T. N.; Rahman, M. S.

10.1101/2024.02.09.579590 — bioinformatics — Posted on 2024-02-12

2987 Sensitive remote homology search by local alignment of small positional embeddings from protein language models

Johnson, S. R.; Peshwa, M.; Sun, Z.

10.1101/2023.07.26.550718 — bioinformatics — Posted on 2024-02-12

2988 Multiplex generation and single cell analysis of structural variants in a mammalian genome

Pinglay, S.; Lalanne, J.-B.; Daza, R. M.; Koeppel, J.; Li, X.; Lee, D. S.; Shendure, J.

10.1101/2024.01.22.576756 — genomics — Posted on 2024-02-12

2989 Arktos: a simple tool for the design of polyhedral DNA nanostructures

Balaji, H.; Samprathi, A. H.; Kolipakala, R. S.; Pradeep, P.; Nagarajan, D.

10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-12

2990 Guided Differentiation of Pluripotent Stem Cells for Cardiac Cell Diversity

McIntire, E.; Barr, K. A.; Gonzales, N. M.; Gilad, Y.

10.1101/2023.07.21.550072 — genomics — Posted on 2024-02-12

2991 PLAPT: Protein-Ligand Binding Affinity Prediction Using Pretrained Transformers

Rose, T. A.; Monti, N.; Anand, N.; Shen, T.

10.1101/2024.02.08.575577 — bioinformatics — Posted on 2024-02-12

2992 TopoQual polishes circular consensus sequencing data and accurately predicts quality scores

Weerakoon, M.; Heaton, H.; Lee, S.; Mitchell, E.

10.1101/2024.02.08.579541 — bioinformatics — Posted on 2024-02-12

2993 Natural variation in infection specificityof Caenorhabditis briggsae isolates by two RNA viruses

Alkan, C.; Bresard, G.; Frezal, L.; Richaud, A.; Ruaud, A.; Zhang, G.; Felix, M.-A.

10.1101/2024.02.10.579610 — genetics — Posted on 2024-02-12

2994 Federated Learning for multi-omics: a performance evaluation in Parkinson's disease

Danek, B. P.; Makarious, M. B.; Dadu, A.; Vitale, D.; Lee, P. S.; Nalls, M. A.; Sun, J.; Faghri, F.

10.1101/2023.10.04.560604 — bioinformatics — Posted on 2024-02-12

2995 Causal mediation analysis for time-varying heritable risk factors with Mendelian Randomization

Wu, Z.; Lewis, E.; Zhao, Q.; Wang, J.

10.1101/2024.02.10.579129 — genetics — Posted on 2024-02-12

2996 X-chromosome loss rescues Sertoli cell maturation and spermatogenesis in Klinefelter syndrome

Winge, S. B.; Skakkebaek, N. E.; Aksglaede, L.; Saritas, G.; Rajpert-De Meyts, E.; Goossens, E.; Juul, A.; Almstrup, K.

10.1101/2024.02.09.576184 — genetics — Posted on 2024-02-12

2997 Using machine learning to integrate genetic and environmental data to model genotype-by-environment interactions

Fernandes, I. K.; Vieira, C. C.; Dias, K. O. d. G.; Fernandes, S. B.

10.1101/2024.02.08.579534 — genetics — Posted on 2024-02-12

2998 Heritability within groups is uninformative about differences among groups: cases from behavioral, evolutionary, and statistical genetics

Schraiber, J. G.; Edge, M. D.

10.1101/2023.11.06.565864 — genetics — Posted on 2024-02-12

2999 Evolutionary and biological mechanisms underpinning chitin degradation in aquatic fungi

Chrismas, N.; Bird, K.; Laundon, D.; Hesketh-Best, P.; Lieng, C.; Cunliffe, M.

10.1101/2024.02.10.579206 — evolutionary biology — Posted on 2024-02-12

3000 Polygenic basis of field evolved Bt Cry resistance in the corn earworm, Helicoverpa zea

Taylor, K. L.; Quackenbush, J.; Lamberty, C.; Hamby, K. A.; Fritz, M. L.

10.1101/2024.02.09.579652 — evolutionary biology — Posted on 2024-02-12

3001 The Fossilised Birth-Death Model is Identifiable

Truman, K.; Vaughan, T. G.; Gavryushkin, A.; Gavryushkina, A.

10.1101/2024.02.08.579547 — evolutionary biology — Posted on 2024-02-12

3002 Host-specific effects of a generalist parasite of mosquitoes

G. Zeferino, T.; C. Koella, J.

10.1101/2024.02.09.579598 — evolutionary biology — Posted on 2024-02-12

3003 Trehalose mediates salinity-stress tolerance in a crustacean

Santos, J. L.; Nick, F.; Adhitama, N.; Fields, P. D.; Stillman, J. H.; Kato, Y. L.; Watanabe, H.; Ebert, D.

10.1101/2024.02.09.579427 — evolutionary biology — Posted on 2024-02-12

3004 Phylogeny and divergence time estimation of Io moths and relatives (Lepidoptera: Saturniidae: Automeris)

Skojec, C.; Earl, C.; Couch, C. D.; Kawahara, A. Y.

10.1101/2023.08.02.551698 — evolutionary biology — Posted on 2024-02-12

3005 Advancements in monitoring: a comparison of traditional and application-based tools for measuring outdoor recreation

Vilalta Capdevila, T.; McLellan, B. A.; Loosen, A.; Forshner, A.; Pigeon, K.; Jacob, A. L.; Wright, P.; Ehlers, L.

10.1101/2024.02.09.579662 — ecology — Posted on 2024-02-12

3006 Variable responses of individual species to tropical forest degradation

Ewers, R. M.; Pearse, W. D.; Orme, C. D. L.; Amarasekare, P.; De Lorm, T.; Granville, N.; Adzhar, R.; Aldridge, D. C.; Ancrenaz, M.; Atton, G.; Barclay, H.; Barclay, M. L.; Bernard, H.; Bicknell, J. E.; Bishop, T. R.; Blackman, J.; Both, S.; Boyle, M. W.; Brant, H.; Brasington, E.; Burslem, D.; Bush, E. R.; Calloway, K.; Carbone, C.; Cator, L.; Chapman, P. M.; Chey, V.; Chung, A.; Clare, E. L.; Cusack, J.; Dancak, M.; Davies, Z. G.; Davison, C. W.; Dawood, M. M.; Deere, N. J.; Dickinson, K. M.; Didham, R. K.; Dobert, T. F.; Dow, R. A.; Drinkwater, R.; Edwards, D. P.; Eggleton, P.; Faruk, A.; F

10.1101/2024.02.09.576668 — ecology — Posted on 2024-02-12

3007 Global niche partitioning of purine and pyrimidine cross-feeding among ocean microbes

Braakman, R.; Satinsky, B.; O'Keefe, T. J.; Longnecker, K.; Becker, J. W.; Dooley, K.; Hogle, S. L.; Arellano, A.; Kido Soule, M. C.; Kujawinski, E. B.; Chisholm, S. W.

10.1101/2024.02.09.579562 — ecology — Posted on 2024-02-12

3008 Hamster (Cricetus cricetus) and ground squirrel (Spermophilus citellus) in the metropolitan area of Vienna, Austria: Urban development vs. species protection

Rubel, F.

10.1101/2024.02.08.579520 — ecology — Posted on 2024-02-12

3009 PDG-Arena: An ecophysiological model for characterizing tree-tree interactions in heterogeneous stands

Rouet, C.; Davi, H.; Druel, A.; Fady, B.; Morin, X.

10.1101/2024.02.09.579667 — ecology — Posted on 2024-02-12

3010 Insights into the nature of the microalgal toxins from the Chrysochromulina leadbeateri blooms in Northern Norwegian fjords

Wang, X.; Fon, M.; Andersen, A. J. C.; Solhaug, A.; Ingebrigtsen, R. A.; Samdal, I. A.; Uhlig, S.; Miles, C. O.; Edvardsen, B.; Larsen, T. O.

10.1101/2024.02.08.576530 — ecology — Posted on 2024-02-12

3011 Time-series metagenomics reveals changing protistan ecology of a temperate dimictic lake

Krinos, A. I.; Bowers, R. M.; Rohwer, R. R.; McMahon, K.; Woyke, T.; Schulz, F.

10.1101/2024.02.09.579653 — ecology — Posted on 2024-02-12

3012 A mechanistic statistical approach to infer invasion characteristics of human-dispersed species with complex life cycle

Goel, N.; Liebhold, A.; Bertelsmeier, C.; Hooten, M.; Korolev, K. S.; Keitt, T.

10.1101/2024.02.09.578762 — ecology — Posted on 2024-02-12

3013 Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

Xiong, F.; Tentner, A. R.; Nandagopal, S.; Hiscock, T. W.; Huang, P.; Megason, S.

10.1101/412858 — developmental biology — Posted on 2024-02-12

3014 Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment

Leech, V.; Kenny, F.; Marcotti, S.; Shaw, T.; Stramer, B.; Manhart, A.

10.1101/2024.02.02.578535 — cell biology — Posted on 2024-02-12

3015 Age-Related Dynamics of Methanogenic Archaea in the Human Gut Microbiome: Implications for Longevity and Health

Mohammadzadeh, R.; Mahnert, A.; Shinde, T.; Kumpitsch, C.; Weinberger, V.; Schmidt, H.; Moissl-Eichinger, C.

10.1101/2024.02.09.579604 — microbiology — Posted on 2024-02-12

3016 Nifuroxazide Suppresses PD-L1 Expression and Enhances the Efficacy of Radiotherapy in Hepatocellular Carcinoma

Zhao, T.; Wei, P.; Zhang, C.; Zhou, S.; Liang, L.; Guo, S.; Yin, Z.; Cheng, S.; Gan, Z.; Xia, Y.; Zhang, Y.; Guo, S.; Zhong, J.; Yang, Z.; Tu, F.; Wang, Q.; Bai, J.; Ren, F.; Feng, Z.; Jia, H.

10.1101/2023.09.03.556121 — immunology — Posted on 2024-02-12

3017 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis

Park, B.; Nicaise, A.; Tsitsipatis, D.; Pirvan, L.; Prasad, P.; Larraz Lopez De Novales, M.; Whitten, J.; Culig, L.; Llewellyn, J.; Ionescu, R.-B.; Willis, C.; Krzak, G.; Fan, J.; De, S.; Suarez Cubero, M.; Spathopoulou, A.; Peruzzotti-Jametti, L.; Leonardi, t.; Edenhofer, F.; Gorospe, M.; Mohorianu, I.; Pluchino, S.; Beerman, I.

10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-12

3018 The highly repetitive genome of Myxobolus rasmusseni n. sp, a myxozoan parasite of fathead minnows

Muthye, V. R.; Leon Coria, A.; Liu, H.; Finney, C. A. M.; Goater, C. P.; Wasmuth, J. D.

10.1101/2024.02.09.579586 — zoology — Posted on 2024-02-12

3019 Uncovering functional lncRNAs by scRNA-seq with ELATUS

Goni, E.; Mas, A. M.; Abad, A.; Santisteban, M.; Fortes, P.; Huarte, M.; Hernaez, M.

10.1101/2024.01.26.577344 — bioinformatics — Posted on 2024-02-12

3020 Real-time Imaging of Decompression Gas Bubble Growth in the Spinal Cord of Live Rats

Alvarado, R.; Scheven, U. M.; Meiners, J.-C.

10.1101/2024.02.09.578916 — bioengineering — Posted on 2024-02-12

3021 Predator cues and environmental enrichment during development drive intraspecific variation in the behaviour and life-history of juvenile lobsters

Polverino, G.; Latini, L.; Nascetti, G.; Grignani, G.; Bello, E.; Gili, C.; Carere, C.; Canestrelli, D.

10.1101/2024.02.10.578266 — animal behavior and cognition — Posted on 2024-02-12

3022 Natural disaster alters the adaptive benefits of sociality in a primate

Testard, C.; Shergold, C.; Acevedo-Ithier, A.; Hart, J.; Negron-Del Valle, J.; Philips, D.; Bernau, A.; Watowich, M.; Sanguinetti-Scheck, J. I.; Montague, M.; Snyder-Mackler, N. J.; Higham, J.; Platt, M.; Brent, L. J.

10.1101/2023.07.17.549328 — animal behavior and cognition — Posted on 2024-02-12

3023 An adaptable, user-friendly score sheet to monitor welfare in experimental fish

Flueck, M.; Schmidt-Posthaus, H.; Bergadano, A.; Adrian-Kalchhauser, I.

10.1101/2023.07.19.549642 — animal behavior and cognition — Posted on 2024-02-12

3024 Ubiquity of inverted 'gelatinous' ecosystem pyramids in the global ocean

Lombard, F.; Guidi, L.; Brandao, M. C.; Coelho, L. P.; Colin, S.; Dolan, J. R.; Elineau, A.; Gasol, J. M.; Grondin, P. L.; Henry, N.; Ibarbalz, F. M.; Jalabert, L.; Loreau, M.; Martini, S.; Meriguet, Z.; Picheral, M.; Pierella Karlusich, J. J.; Rainer, P.; Romagnan, J.-B.; Zinger, L.; Tara Oceans Coordinators, ; Stemmann, L.; Acinas, S.; Karp-Boss, L.; Boss, E.; Sullivan, M. B.; de Vargas, C.; Bowler, C.; Karsenti, E.; Gorsky, G.

10.1101/2024.02.09.579612 — ecology — Posted on 2024-02-12

3025 Coastal marine mammal conservation using thermal imaging-based detection systems

Richter, S.; Yurk, H.; Winterl, A.; Chmelnitsky, E.; Serra-Sogas, N.; O'Hara, P. D.; Zitterbart, D. P.

10.1101/2023.08.25.554754 — ecology — Posted on 2024-02-12

3026 The deubiquitylating enzyme Fat Facets promotes Fat signalling and restricts tissue growth

Dawson, L. E.; Fulford, A. D.; Sekar, A.; Ribeiro, P. S.

10.1101/2024.01.27.577535 — developmental biology — Posted on 2024-02-12

3027 Extracellular filaments revealed by affinity capture cryo-electron tomography of lymphocytes

Engel, L.; Zaoralova, M.; Zhou, M.; Dunn, A. R.; Oliver, S. L.

10.1101/2023.08.05.552110 — cell biology — Posted on 2024-02-12

3028 Similar mechanisms of retron-mediated anti-phage defense for different families of tailed phages

Garcia-Rodriguez, F. M.; Martinez Abarca, F.; Wilkinson, M. E.; Toro, N.

10.1101/2024.02.09.579579 — microbiology — Posted on 2024-02-12

3029 Cell non-autonomous signaling through the conserved C. elegans glycopeptide hormone receptor FSHR-1 regulates cholinergic neurotransmission

Buckley, M.; Jacob, W. P.; Bortey, L.; McClain, M. R.; Ritter, A. L.; Godfrey, A.; Munneke, A. S.; Ramachandran, S.; Kenis, S.; Kolnik, J. C.; Olofsson, S.; Adkins, R.; Kutoloski, T.; Rademacher, L.; Heinecke, O.; Alva, A.; Beets, I.; Francis, M.; Kowalski, J. R.

10.1101/2024.02.10.578699 — neuroscience — Posted on 2024-02-12

3030 Selective attention to audiovisual speech is associated with recurrent feedback-feedforward loops in the ventral processing stream

Wikman, P.; Salmela, V.; Sjoblom, E.; Leminen, M.; Laine, M.; Alho, K.

10.1101/2023.07.17.549287 — neuroscience — Posted on 2024-02-12

3031 Semi-supervised Bayesian integration of multiple spatial proteomics datasets

Coleman, S. D.; Breckels, L.; Waller, R. F.; Lilley, K. S.; Wallace, C.; Kirk, P. D. W.; Crook, O. M.

10.1101/2024.02.08.579519 — systems biology — Posted on 2024-02-12

3032 High-throughput phenotyping reveals multiple drought responses of wild and cultivated Phaseolinae beans

Verheyen, J.; Dhondt, S.; Abbeloos, R.; Eeckhout, J.; Janssens, S.; Leyns, F.; Scheldeman, X.; Storme, V.; Vandelook, F.

10.1101/2024.02.09.579595 — plant biology — Posted on 2024-02-12

3033 A Prodrug Strategy to Reposition Atovaquone as a Long-Acting Injectable for Malaria Chemoprotection

Gupta, A. K.; Eliasen, A. M.; Andahazy, W.; Zhou, F.; Henson, K.; Chi, V.; Woods, A. K.; Joseph, S. B.; Kuhen, K. L.; Wisler, J.; Ramachandruni, H.; Duffy, J.; Burrows, J. N.; Vadas, E.; Slade, A.; Schultz, P. G.; McNamara, C. W.; Chatterjee, A. K.

10.1101/2024.02.08.579395 — pharmacology and toxicology — Posted on 2024-02-12

3034 Molecular determinants of antagonist interactions with chemokine receptors CCR2 and CCR5

Dawson, J. R. D.; Wadman, G. M.; Zhang, P.; Tebben, A. J.; Carter, P. H.; Gu, S.; Shroka, T.; Borrega-Roman, L.; Salanga, C.; Handel, T. M.; Kufareva, I.

10.1101/2023.11.15.567150 — pharmacology and toxicology — Posted on 2024-02-12

3035 Loss of endogenous estrogen alters mitochondrial metabolism and muscle clock-related protein Rbm20 in female mdx mice

Timpani, C. A.; Debrincat, D.; Kourakis, S.; Boyer, R.; Formosa, L. E.; Steele, J. R.; Zhang, H.; Schittenhelm, R. B.; Russell, A. P.; Rybalka, E.; Lindsay, A.

10.1101/2024.02.08.579567 — pathology — Posted on 2024-02-12

3036 Optical photothermal infrared spectroscopy (O-PTIR): a promising new tool for bench-top analytical palaeontology at the sub-micron scale

Loron, C. C.; Borondics, F.

10.1101/2024.02.08.579492 — paleontology — Posted on 2024-02-12

3037 Integrating Dynamic Network Analysis with AI for Enhanced Epitope Prediction in PD-L1:Affibody Interactions

Gomes, D. E. B.; Yang, B.; Vanella, R.; Nash, M. A.; Bernardi, R. C.

10.1101/2024.02.08.579577 — biophysics — Posted on 2024-02-11

3038 Transcriptomic Signatures of WNT-Driven Pathways and Granulosa Cell-Oocyte Interactions during Primordial Follicle Activation

Takase, H. M.; Mishina, T.; Hayashi, T.; Yoshimura, M.; Kuse, M.; Nikaido, I.; Kitajima, T. S.

10.1101/2024.02.08.579446 — bioinformatics — Posted on 2024-02-11

3039 Simpler protein domain identification using spectral clustering

Cazals, F.; Herrmann, J.; Sarti, E.

10.1101/2024.02.10.579762 — bioinformatics — Posted on 2024-02-11

3040 The Genotype and Phenotypes in Families (GPF) platform manages the large and complex data at SFARI

Chorbadjiev, L.; Cokol, M.; Weinstein, Z.; Shi, K.; Fleisch, C.; Dimitrov, N.; Mladenov, S.; Xu, S.; Hall, J.; Ford, S.; Lee, Y.-h.; Yamrom, B.; Marks, S.; Munoz, A.; Lash, A.; Volfovsky, N.; Iossifov, I.

10.1101/2024.02.08.579330 — bioinformatics — Posted on 2024-02-11

3041 Characterisation of RNA editing and gene therapy with a compact CRISPR-Cas13 in the retina

Kumar, S.; Hsiao, Y.-W.; Wong, V. H. Y.; Aubin, D.; Wang, J.-H.; Lisowski, L.; Rakoczy, E. P.; Li, F.; Alarcon-Martinez, L.; Gonzalez Cordero, A.; Bui, B. V.; Liu, G.-S.

10.1101/2024.02.10.579778 — molecular biology — Posted on 2024-02-11

3042 mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms

Barnabe, C.; Sempere, G.; Manzanilla, V.; Moo Millan, J.; Amblard-Rambert, A.; Waleckx, E.

10.1101/2024.02.08.579441 — bioinformatics — Posted on 2024-02-11

3043 Accurate Assembly of Circular RNAs with TERRACE

Zahin, T.; Shi, Q.; Zang, X. C.; Shao, M.

10.1101/2024.02.09.579380 — bioinformatics — Posted on 2024-02-11

3044 Drug-induced cytotoxicity prediction in muscle cells, an application of the Cell Painting assay

Lambert, R.; Serrano Candelas, E.; Aparicio, P.; Murphy, A.; Gozalbes, R.; Fearnhead, H. O.

10.1101/2024.02.08.579439 — bioinformatics — Posted on 2024-02-11

3045 TTF1 control of LncRNA synthesis and cell growth delineates a tumour suppressor pathway acting directly on the ribosomal RNA Genes

Sibai, D. S.; Tremblay, M. G.; Lessard, F.; Tav, C.; Sabourin-Felix, M.; Robinson, M. D.; Moss, T.

10.1101/2024.02.11.579707 — molecular biology — Posted on 2024-02-11

3046 Endothelial fatty acid-binding proteins contribute to the pathogenesis of pulmonary hypertension

Liu, B.; Yi, D.; Li, S.; Ramirez, K.; Xia, X.; Cao, Y.; Zhao, H.; Tripathi, A.; Qiu, S.; Kala, M.; Rafikov, R.; Gu, H.; Perez, V. d. j.; Lemay, S.-E.; Glembotski, C. C.; Knox, K. S.; Kalinichenko, V. V.; Bonnet, S.; Fallon, M. B.; Boucherat, O.; Dai, Z.

10.1101/2024.02.11.579846 — molecular biology — Posted on 2024-02-11

3047 PLA-complexity of k-mer multisets

Abrar, M. H.; Medvedev, P.

10.1101/2024.02.08.579510 — bioinformatics — Posted on 2024-02-11

3048 Breakthrough in Dicot Prime Editing: Enabling Heritable Desired Edits in Tomato and Arabidopsis

Vu, T. V.; Nguyen, N. T.; Kim, J.; Song, Y. J.; Nguyen, T. H.; Kim, J.-Y.

10.1101/2024.02.11.579803 — synthetic biology — Posted on 2024-02-11

3049 Profiling IOP-responsive genes in anterior and posterior ocular tissues in the rat CEI glaucoma model

Lozano, D. C.; Yang, Y.-F.; Cepurna, W. O.; Smoody, B. F.; Ing, E.; Morrison, J. C.; Keller, K. E.

10.1101/2024.02.11.579818 — molecular biology — Posted on 2024-02-11

3050 Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging

Frei, M. S.; Sanchez, S. A.; Liu, L.; Schneider, F.; Wang, Z.; Hakozaki, H.; Li, Y.; Lyons, A. C.; Rohm, T. V.; Olefsky, J. M.; Shi, L.; Schöneberg, J.; Fraser, S. E.; Mehta, S.; Wang, Y.; Zhang, J.

10.1101/2024.02.10.579766 — bioengineering — Posted on 2024-02-11

3051 Sarbecovirus RBD indels and specific residues dictating ACE2 multi-species adaptiveness

Si, J.; Chen, Y.; Gu, M.; Sun, Y.; Huang, M.; Shi, L.; Yu, X.; Yang, X.; Xiong, Q.; Ma, C.; Liu, P.; Shi, Z.-L.; Yan, H.

10.1101/2024.02.11.579781 — microbiology — Posted on 2024-02-11

3052 Macrolactin A Is an Inhibitor of Protein Biosynthesis in Bacteria

Vasilchenko, A. S.; Lukyanov, D. A.; Dilbaryan, D. S.; Usachev, K. S.; Poshvina, D. V.; Nikandrova, A. A.; Imamutdinova, A. N.; Garaeva, N. S.; Bikmullin, A. G.; Klochkova, E. A.; Taldaev, A.; Rusanov, A. L.; Romashin, D. D.; Luzgina, N. G.; Osterman, I. A.; Sergiev, P. V.; Teslya, A. V.

10.1101/2024.02.10.575802 — microbiology — Posted on 2024-02-11

3053 Restricting CAR T Cell Trafficking Expands Targetable Antigen Space

Morales, E. A.; Dietze, K. A.; Baker, J. M.; Wang, A.; Avila, S. V.; Iglesias, F.; Radhakrishnan, S. V.; Vander Mause, E.; Olson, M. L.; Sun, W.; Rosati, E.; Chidester, S. L.; Iraguha, T.; Fan, X.; Atanackovic, D.; Luetkens, T.

10.1101/2024.02.08.579002 — bioengineering — Posted on 2024-02-11

3054 Microsporidian coinfection reduces fitness of a fungal pathogen due to rapid host mortality

Dziuba, M. K.; McIntire, K. M.; Davenport, E. S.; Baird, E.; Huerta, C.; Jaye, R.; Corcoran, F. E.; McCreadie, P.; Nelson, T.; Duffy, M. A.

10.1101/2024.02.08.579564 — ecology — Posted on 2024-02-11

3055 Acrylate reductase of an anaerobic electron transport chain of the marine bacterium Shewanella woodyi

Bertsova, Y. V.; Serebryakova, M. V.; Bogachev, V. A.; Baykov, A. A.; Bogachev, A. V.

10.1101/2024.02.11.579808 — biochemistry — Posted on 2024-02-11

3056 Congenital T cell activation impairs transitional to follicular B cell maturation in humans

Allard-Chamard, H.; Hillier, K.; Ramseier, M. L.; Bertocchi, A.; Kaneko, N.; Premo, K.; Lam, T.; Yuen, G.; Karpel, M.; Mahajan, V. S.; Tsekeri, C.; Vencic, J.; Crotty, R.; Sharda, A.; Barmettler, S.; Westermann-Clark, E.; Walter, J. E.; Ghebremichael, M.; Shalek, A. K.; Farmer, J. R.; Pillai, S.

10.1101/2024.02.08.579495 — immunology — Posted on 2024-02-11

3057 A genome wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6

Tung, J.; Huang, L.; George, G.; Harding, H. P.; Ron, D.; Ordonez, A.

10.1101/2024.02.10.579381 — cell biology — Posted on 2024-02-11

3058 navigate: an open-source platform for smart light-sheet microscopy.

Marin, Z.; Wang, X.; Collison, D. W.; McFadden, C.; Lin, J.; Borges, H.; Chen, B.; Mehra, D.; Shen, Q.; Galecki, S.; Daetwyler, S.; Fiolka, R. P.; Dean, K. M.

10.1101/2024.02.09.579083 — biophysics — Posted on 2024-02-11

3059 Conformational basis of subtype-specific allosteric control of NMDA receptor gating

Bleier, J.; Ribeiro Furtado de Mendonca, P.; Habrian, C.; Stanley, C.; Vyklicky, V.; Isacoff, E. Y.

10.1101/2024.02.10.579740 — biophysics — Posted on 2024-02-11

3060 A live cell imaging-based assay for tracking particle uptake by clathrin-mediated endocytosis

Ashby, G.; Keng, K. E.; Hayden, C. C.; Stachowiak, J.

10.1101/2024.02.08.579544 — biophysics — Posted on 2024-02-11

3061 Phospho-KNL-1 recognition by a TPR domain targets the BUB-1/BUB-3 complex to C. elegans kinetochores

Houston, J.; Vissotsky, C.; Deep, A.; Hakozaki, H.; Crews, E.; Oegema, K.; Corbett, K. D.; Lara-Gonzalez, P.; Kim, T.; Desai, A.

10.1101/2024.02.09.579536 — cell biology — Posted on 2024-02-11

3062 Single molecule imaging of the central dogma reveals myosin-2A gene expression is regulated by contextual translational buffering

Wiggan, O.; Stasevich, T. J.

10.1101/2024.02.11.579797 — cell biology — Posted on 2024-02-11

3063 Identification of a motif in TPX2 that regulates spindle architecture in Xenopus egg extracts

Pena, G.; Zhou, X.; Slevin, L.; Brownlee, C.; Heald, R.

10.1101/2024.02.10.579770 — cell biology — Posted on 2024-02-11

3064 Substrate recognition principles for PP2A-B55

Kruse, T.; Garvanska, D.; Varga, J. K.; Garland, W.; McEwan, B.; Hein, J.; Weisser, M. B.; Brandies Puy, I.; Chan, C.; Parrila, P. S.; Lopez-Mendez, B.; Jeyaprakash, A. A.; Schueler-Furman, O.; Jensen, T. H.; Kettenbach, A.; Nilsson, J.

10.1101/2024.02.10.579793 — cell biology — Posted on 2024-02-11

3065 Interactors and effects of overexpressing YlxR/RpnM, a conserved RNA binding protein in cyanobacteria

Hemm, L.; Miucci, A.; Riediger, M.; Tholen, S.; Kraus, A.; Georg, J.; Schilling, O.; Hess, W. R.

10.1101/2024.01.06.574455 — microbiology — Posted on 2024-02-11

3066 αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

Uboveja, A.; Huang, Z.; Buj, R.; Amalric, A.; Wang, H.; Tangudu, N. K.; Cole, A. R.; Megill, E.; Kantner, D.; Chatoff, A.; Ahmad, H.; Marcinkiewicz, M. M.; Disharoon, J. A.; Graff, S.; Dahl, E. S.; Hempel, N.; Stallaert, W.; Sidoli, S.; Bitler, B. G.; Long, D. T.; Snyder, N. W.; Aird, K. M.

10.1101/2024.02.06.578742 — cancer biology — Posted on 2024-02-11

3067 Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

Algranati, D.; Oren, R.; Dassa, B.; Fellus-Alyagor, L.; Plotnikov, A.; Barr, H.; Harmelin, A.; London, N.; Ron, G.; Furth, N.; Shema, E.

10.1101/2024.02.05.578974 — cancer biology — Posted on 2024-02-11

3068 VHL Mutation Drives Human Clear Cell Renal Cell Carcinoma Progression Through PI3K/AKT-Dependent Cholesteryl Ester Accumulation

Zhang, S.; Fang, T.; He, Y.; Feng, W.; Yu, Z.; Zheng, Y.; Zhang, C.; Hu, S.; Liu, Z.; Liu, J.; Yu, J.; Zhang, H.; He, A.; Gong, Y.; He, Z.; Yang, K.; Xi, Z.; Yu, W.; Zhou, L.; Yao, L.; Yue, S.

10.1101/2023.01.02.522447 — cancer biology — Posted on 2024-02-11

3069 Controllable Protein Design by Prefix-Tuning Protein Language Models

Luo, J.; Liu, X.; Li, J.; Chen, Q.; Chen, J.

10.1101/2023.12.03.569747 — bioinformatics — Posted on 2024-02-11

3070 Mitochondrial mutation spectrum in Chordates: damage versus replication signatures, causes, and dynamics

Iliushchenko, D.; Efimenko, B.; Mikhailova, A. G.; Shamanskiy, V.; Saparbaev, M.; Mazunin, I.; Knorre, D.; Kunz, W.; Kapranov, P.; Denisov, S.; Khrapko, K.; Fellay, J.; Gunbin, K.; Popadin, K.

10.1101/2023.12.08.570826 — bioinformatics — Posted on 2024-02-11

3071 Multiplex Single-Cell Bioprinting for Engineering of Heterogeneous Tissue Constructs with Subcellular Spatial Resolution

Helms, H. R.; Oyama, K. A.; Ware, J. P.; Ibsen, S. D.; Bertassoni, L. E.

10.1101/2024.02.01.578499 — bioengineering — Posted on 2024-02-11

3072 Whole genome regulatory effect of MoISW2 and consequences for the evolution of rice plant pathogenic fungus Magnaporthe oryzae

Pei, M.; Abubakar, Y. S.; Ali, H.; Lin, L.; Dou, X.; Lu, G.; Wang, Z.; Li, Y.; Olsson, S.

10.1101/2022.02.27.481874 — evolutionary biology — Posted on 2024-02-11

3073 Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP.

Mulligan, R. J.; Magaj, M. M.; Digilio, L.; Redemann, S.; Yap, C. C.; Winckler, B.

10.1101/2023.10.24.563658 — cell biology — Posted on 2024-02-11

3074 Learned response dynamics reflect stimulus timing and encode temporal expectation violations in superficial layers of mouse V1

Knudstrup, S. G.; Martinez Reyes, C.; Gavornik, J. P.

10.1101/2024.01.20.576433 — neuroscience — Posted on 2024-02-11

3075 Increased Cholesterol Synthesis Drives Neurotoxicity in Patient Stem Cell-Derived Model of Multiple Sclerosis

Ionescu, R.-B.; Nicaise, A. M.; Reisz, J. A.; Williams, E. C.; Prasad, P.; Dzieciatkowska, M.; Stephenson, D.; Suarez Cubero, M.; Pirvan, L.; Willis, C. M.; Peruzzotti-Jametti, L.; Fossati, V.; Edenhofer, F.; Leonardi, t.; Frezza, C.; Mohorianu, I.; D'Alessandro, A.; Pluchino, S.

10.1101/2024.01.16.575826 — neuroscience — Posted on 2024-02-11

3076 Evaluating the transmission risk of amyloid beta peptide via ingestion

Raine, J.; Tolwinski, N.; Gruber, J.; Mathuru, A.

10.1101/2023.08.03.551437 — neuroscience — Posted on 2024-02-11

3077 Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers

Rose, K. N.; Zorlu, M.; Xue, X.; Fassini, A.; Cai, W.; Lin, S.; Webb, P. K.; Schwarzschild, M.; Chen, X.; Gomperts, S. N.

10.1101/2023.05.27.542565 — neuroscience — Posted on 2024-02-11

3078 A comprehensive study of light quality acclimation in Synechocystis sp.PCC 6803

Zavrel, T.; Segecova, A.; Kovacs, L.; Lukes, M.; Novak, Z.; Pohland, A. C.; Szabo, M.; Somogyi, B.; Prasil, O.; Cerveny, J.; Bernat, G.

10.1101/2023.06.08.544187 — plant biology — Posted on 2024-02-11

3079 Biomolecular condensates form spatially inhomogeneous network fluids

Dar, F.; Cohen, S. R.; Mitrea, D. M.; Phillips, A. H.; Nagy, G.; Leite, W. C.; Stanley, C. B.; Choi, J.-M.; Kriwacki, R. W.; Pappu, R. V.

10.1101/2023.10.07.561338 — biophysics — Posted on 2024-02-11

3080 Identification of novel buffering mechanisms in aortic arch artery development and congenital heart disease.

Ramirez, A.; Vyzas, C.; Eng, K.; Degenhardt, K.; Astrof, S.

10.1101/2023.03.02.530833 — developmental biology — Posted on 2024-02-11

3081 Exploring the impact of interthalamic adhesion on human cognition: insights from healthy subjects and thalamic stroke patients

Vidal, J. P.; Rachita, K.; Servais, A.; Peran, P.; Pariente, J.; Bonneville, F.; Albucher, J.-F.; Danet, L.; Barbeau, E. J.

10.1101/2024.02.08.579448 — neuroscience — Posted on 2024-02-11

3082 The Mouse Inferior Colliculus Responds Preferentially to Non-Ultrasonic Vocalizations

Tehrani, M.; Shanbhag, S.; Huyck, J.; Patel, R.; Kazimierski, D.; Wenstrup, J.

10.1101/2024.02.09.579664 — neuroscience — Posted on 2024-02-11

3083 DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time

Relovska, S.; Wang, H.; Zhang, X.; Fernandez-Tussy, P.; Jeong, K.; Choi, J.; Suarez, Y.; McDonald, J.; Fernandez-Hernando, C.; Chung, J.-J.

10.1101/2023.12.21.572851 — cell biology — Posted on 2024-02-11

3084 Spatial propagation of temperate phages within and among biofilms

Winans, J.; Garcia, S.; Zeng, L.; Nadell, C.

10.1101/2023.12.20.571119 — microbiology — Posted on 2024-02-11

3085 CoCoNuTs: A diverse subclass of Type IV restriction systems predicted to target RNA

Bell, R. T.; Sahakyan, H.; Makarova, K. S.; Wolf, Y. I.; Koonin, E. V.

10.1101/2023.07.31.551357 — microbiology — Posted on 2024-02-11

3086 A detailed dissection of the expression, localization, structure, and diagnostic potential of cyst wall proteins of the eye pathogen Acanthamoeba

Kanakapura Sundararaj, B.; Goyal, M.; Samuelson, J.

10.1101/2024.02.02.578540 — microbiology — Posted on 2024-02-11

3087 A non-invasive method to sample immune cells in the lower female genital tract using menstrual discs

Peters, M. Q.; Domenjo-Vila, E.; Carlson, M.; Armistead, B.; Edlefsen, P. T.; Gasper, M.; Dabee, S.; Whidbey, C.; Jaspan, H. B.; Prlic, M.; Harrington, W. E.

10.1101/2023.11.16.567469 — immunology — Posted on 2024-02-11

3088 Developmental and molecular contributions to contextual fear memory emergence in mice

Lanjewar, A. L.; Levitt, P.; Eagleson, K. L.

10.1101/2023.02.03.527024 — neuroscience — Posted on 2024-02-11

3089 Spatial interactions modulate tumor growth and immune infiltration

Marzban, S.; Srivastava, S.; Kartika, S.; Bravo, R.; Safriel, R.; Zarski, A.; Anderson, A. R. A.; Chung, C. H.; Amelio, A. L.; West, J.

10.1101/2024.01.10.575036 — cancer biology — Posted on 2024-02-11

3090 ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through modulation of RAD51 and DNA-PKcs-dependent pathways

Li, H.; Chatla, S.; Liu, X.; Tian, Z.; Vekariya, U.; Wang, P.; Kim, D.; Octaviani, S.; Walt, M.; Lian, Z.; Morton, G.; Feng, Z.; Yang, D.; Yang, D.; Liu, H.; Sullivan-Reed, K.; Childers, W.; Yu, X.; Chitrala, K. N.; Madzo, J.; Skorski, T.; Huang, J.

10.1101/2022.09.29.510119 — cancer biology — Posted on 2024-02-11

3091 Small LEA proteins as an effective air-water interface protectant for fragile samples during cryo-EM grid plunge freezing

Abe, K. M.; Lim, C. J.

10.1101/2024.02.06.579238 — biophysics — Posted on 2024-02-11

3092 Fascin structural plasticity mediates flexible actin bundle construction

Gong, R.; Reynolds, M. J.; Carney, K. R.; Hamilton, K.; Bidone, T. C.; Alushin, G. M.

10.1101/2024.01.03.574123 — biophysics — Posted on 2024-02-11

3093 Eukfinder: a pipeline to retrieve microbial eukaryote genomes from metagenomic sequencing data.

Zhao, D.; Salas-Leiva, D. E.; Williams, S. K.; Dunn, K. A.; Roger, A. J.

10.1101/2023.12.28.573569 — bioinformatics — Posted on 2024-02-11

3094 Fast and flexible joint fine-mapping of multiple traits via the Sum of Single Effects model

Zou, Y.; Carbonetto, P.; Xie, D.; Wang, G.; Stephens, M.

10.1101/2023.04.14.536893 — genomics — Posted on 2024-02-11

3095 Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome

Nguyen, J.; Win, P. W.; Nagano, T. S.; Shin, E. H.; Newcomb, C.; Arking, D. E.; Castellani, C. A.

10.1101/2024.01.29.577835 — genomics — Posted on 2024-02-11

3096 Rtt107 cooperates with Rad55 or Slx4 to maintain genome stability in Saccharomyces cerevisiae

Brown, J. A. R.; Kobor, M. S.

10.1101/2024.02.05.579050 — genetics — Posted on 2024-02-11

3097 Spatially resolved human kidney multi-omics single cell atlas highlights the key role of the fibrotic microenvironment in kidney disease progression

Abedini, A.; Levinsohn, J. L.; Kloetzer, K.; Dumoulin, B.; Ma, Z.; Frederick, J.; Dhillon, P.; S. Balzer, M.; Shrestha, R.; Liu, H.; Vitale, S.; Devalaraja-Narashimha, K.; Grandi, P.; Bhattacharyya, T.; Hu, E.; S. Pullen, S.; M Boustany-Kari, C.; Guarnieri, P.; Karihaloo, A.; Trum, D.; Yan, H.; Coleman, K.; Palmer, M.; Sarov-Blat, L.; Morton, L.; A. Hunter, C.; Kaestner, K. H.; Li, M.; Susztak, K.

10.1101/2022.10.24.513598 — genetics — Posted on 2024-02-11

3098 Fight not flight: parasites drive the bacterial evolution of resistance, not escape

Blazanin, M.; Moore, J. P.; Olsen, S.; Travisano, M.

10.1101/2023.04.29.538831 — evolutionary biology — Posted on 2024-02-11

3099 Intact genomic copies of envelope carrying retroelements are found widespread across metazoans

Chary, S.; Hayashi, R.

10.1101/2023.10.26.564294 — evolutionary biology — Posted on 2024-02-11

3100 Switch-Like Phosphorylation of WRN Integrates End-Resection with RAD51 Metabolism at Collapsed Replication Forks

Palermo, V.; Malacaria, E.; Semproni, M.; Perdichizzi, B.; Valenzisi, P.; Sanchez, M.; Marini, F.; Pellicioli, A.; Franchitto, A.; Pichierri, P.

10.1101/403808 — cell biology — Posted on 2024-02-11

3101 SHIELD: Skull-shaped hemispheric implants enabling large-scale-electrophysiology datasets in the mouse brain

Bennett, C.; Ouellette, B.; Ramirez, T. K.; Cahoon, A.; Cabasco, H.; Browning, Y.; Lakunina, A.; Lynch, G. F.; McBride, E.; Belski, H.; Gillis, R.; Grasso, C.; Howard, R.; Johnson, T.; Loeffler, H.; Smith, H.; Sullivan, D.; Williford, A.; Caldejon, S.; Durand, S.; Gale, S. D.; Guthrie, A.; Ha, V.; Han, W.; Hardcastle, B.; Mochizuki, C.; Sridhar, A.; Suarez, L.; Swapp, J.; Wilkes, J.; Siegle, J. H.; Farrell, C.; Groblewski, P.; Olsen, S.

10.1101/2023.11.12.566771 — neuroscience — Posted on 2024-02-11

3102 Sex differences in aggression and its neural substrate in a cichlid fish

Jackson, L.; Dumitrascu, M.; Alward, B. A.

10.1101/2023.10.18.562975 — neuroscience — Posted on 2024-02-11

3103 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis

10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-11

3104 Brain Functional Connectivity Correlates of Anomalous Interaction Between Sensorily Isolated Monozygotic Twins

Silberstein, R. B.; Bigelow, F. J.

10.1101/2023.10.18.563012 — neuroscience — Posted on 2024-02-11

3105 40 Hz Steady-State Response in Human Auditory Cortex Is Shaped by GABAergic Neuronal Inhibition

Toso, A.; Wermuth, A. P.; Arazi, A.; Braun, A.; Grent-'t Jong, T.; Uhlhaas, P. J.; Donner, T. H.

10.1101/2023.10.20.563259 — neuroscience — Posted on 2024-02-11

3106 Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

Elofsson, A.; Han, L.; Bianchi, E.; Wright, G. J.; Jovine, L.

10.1101/2023.07.27.550195 — biophysics — Posted on 2024-02-11

3107 PLAPT: Protein-Ligand Binding Affinity Prediction Using Pretrained Transformers

Rose, T. A.; Monti, N.; Anand, N.; Shen, T.

10.1101/2024.02.08.575577 — bioinformatics — Posted on 2024-02-10

3108 Integrating single-cell RNA-seq datasets with substantial batch effects

Hrovatin, K.; Moinfar, A. A.; Zappia, L.; Tejada Lapuerta, A.; Lengerich, B.; Kellis, M.; Theis, F. J.

10.1101/2023.11.03.565463 — bioinformatics — Posted on 2024-02-10

3109 Fragle: Universal ctDNA quantification using deep learning of fragmentomic profiles

Jacobsen Skanderup, A.; Zhu, G.; Rahman, C.; Getty, V.; Baruah, P.; Carrie, H.; Lim, A.; Guo, Y. A.; Poh, Z.; Sim, N.; Abdelmoneim, A.; Cai, Y.; Ho, D.; Thangaraju, S.; Poon, P.; Lau, Y.; Gan, A.; Ng, S.; Odinokov, D.; Koo, S.-L.; Chong, D.; Tay, B.; Tan, T.; Yap, Y.; Chok, A.; Ng, M.; Tan, P.; Tan, D.; Wong, L.; Wong, P.; Tan, I.

10.1101/2023.07.28.550922 — bioinformatics — Posted on 2024-02-11

3110 COATi: statistical pairwise alignment of protein-coding sequences

Garcia Mesa, J. J.; Zhu, Z.; Cartwright, R. A.

10.1101/2023.05.22.541791 — bioinformatics — Posted on 2024-02-11

3111 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays

Van Vranken, J. G.; Li, J.; Mintseris, J.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D.

10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-02-10

3112 A blue mussel chromosome-scale genome assembly for aquaculture, marine ecology and evolution

Regan, T.; Hori, T. S.; Bean, T. P.

10.1101/2022.11.17.516937 — genomics — Posted on 2024-02-10

3113 Considerations for reporting variants in novel candidate genes identified during clinical genomic testing

Chong, J. X.-L.; Berger, S.; Baxter, S.; Smith, E.; Xiao, C.; Calame, D.; Hawley, M.; Rivera-Munoz, E. A.; DiTroia, S.; Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium, ; Bamshad, M.; Rehm, H.

10.1101/2024.02.05.579012 — genetics — Posted on 2024-02-11

3114 Dynamics of the viral community on the cheese surface during maturation and persistence across production years

Thomas, P.; Lamy-Besnier, Q.; Figueroa, C.; Petit, M.-A.; Dugat-Bony, E.

10.1101/2023.11.06.565837 — microbiology — Posted on 2024-02-11

3115 Tonic and phasic transcutaneous auricular Vagus Nerve Stimulation both evoke rapid and transient pupil dilation

Skora, L. I.; Marzecova, A.; Jocham, G.

10.1101/2023.09.20.558607 — neuroscience — Posted on 2024-02-10

3116 Lesions in a songbird vocal circuit increase variability in song syntax

Koparkar, A.; Warren, T. L.; Charlesworth, J. D.; Shin, S.; Brainard, M. S.; Veit, L.

10.1101/2023.07.25.550508 — neuroscience — Posted on 2024-02-10

3117 Neurofeedback training can modulate task-relevant memory replay in rats

Gillespie, A. K.; Astudillo Maya, D. A.; Denovellis, E. L.; Desse, S.; Frank, L. M.

10.1101/2022.10.13.512183 — neuroscience — Posted on 2024-02-11

3118 The spatial landscape of glial pathology and T-cell response in Parkinson's disease substantia nigra

Jakubiak, K.; Paryani, F.; Kannan, A.; Lee, J.; Madden, N.; Li, J.; Chen, D.; Mahajan, A.; Xia, S.; Flowers, X.; Menon, V.; Sulzer, D.; Goldman, J. E.; Sims, P. A.; Al-Dalahmah, O.

10.1101/2024.01.08.574736 — neuroscience — Posted on 2024-02-11

3119 A multiscale sensorimotor model of experience-dependent behavior in a minimal organism

Vidal-Saez, M. S.; Vilarroya, O.; Garcia-Ojalvo, J.

10.1101/2024.02.07.579358 — systems biology — Posted on 2024-02-10

3120 The ultrastructure of the starfish skeleton is correlated with mechanical stress

Raman, R.; Labisch, S.; Dirks, J.-H.

10.1101/2024.02.07.579295 — zoology — Posted on 2024-02-10

3121 Waiting for the Perfect Vaccine

Rost, G.; Wang, Z.; Moghadas, S.

10.1101/2024.02.07.579403 — systems biology — Posted on 2024-02-10

3122 Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages

Pinon, L.; Chabaud, M.; Nivoit, P.; Wong-Ng, J.; Nguyen, T.-T.; Paul, V.; Goussard, S.; Frachon, E.; Obino, D.; Gobaa, S.; Dumenil, G.

10.1101/2024.02.09.579276 — synthetic biology — Posted on 2024-02-10

3123 The ideotype for drought tolerance in bioenergy Populus nigra

Smith, H. K.; Puertolas, J.; Douthe, C.; Emiliani, G.; Giovannelli, A.; Rowland, L. S.; Allwright, M.; Bailey-Bale, J. H.; Valdes-Fragoso, P. M.; Larsen, E. K.; Alberti, G.; Zaldei, A.; Hirons, A. D.; Alasia, F.; Ribas-Carbo, M.; Flexas, J.; Dodd, I. C.; Davies, W. J.; Taylor, G.

10.1101/2024.02.07.579233 — plant biology — Posted on 2024-02-10

3124 Anti-diuretic hormone ITP signals via a guanylate cyclase receptor to modulate systemic homeostasis in Drosophila

Gera, J.; Agard, M.; Nave, H.; Sajadi, F.; Thorat, L.; Kondo, S.; Nassel, D.; Paluzzi, J.-P. V.; Zandawala, M.

10.1101/2024.02.07.579245 — physiology — Posted on 2024-02-10

3125 Age, not body size, influences flight distance in the bumble bee Bombus terrestris L. (Hymenoptera: Apidae)

Gilgenreiner, M.; Kurze, C.

10.1101/2024.02.07.579366 — physiology — Posted on 2024-02-10

3126 A common set of structurally distinct endogenous retroviruses predict survival in multiple human tumor types

Massa, A. L.; Chintalapudi, H.; Coppenbarger, E. C.; Peterson, J. M.; Moss, W. N.; Frost, H. R.; Leach, S. D.

10.1101/2024.02.07.579350 — cancer biology — Posted on 2024-02-10

3127 Single Nucleotide Polymorphism (SNP) and Antibody-based Cell Sorting (SNACS): A tool for demultiplexing single-cell DNA sequencing data

Kennedy, V. E.; Roy, R.; Peretz, C.; Koh, A.; Tran, E.; Smith, C.; Olshen, A.

10.1101/2024.02.07.579345 — bioinformatics — Posted on 2024-02-10

3128 Tests for Segregation Distortion in Tetraploid F1 Populations

Gerard, D.; Thakkar, M.; Ferrao, L. F. V.

10.1101/2024.02.07.579361 — bioinformatics — Posted on 2024-02-10

3129 Utility of an untargeted metabolomics approach using a 2D GC-GC-MS platform to distinguish relapsing and progressive multiple sclerosis

Datta, I.; Zahoor, I.; Ata, N.; Rashid, F.; Cerghet, M.; Rattan, R.; Poisson, L.; Giri, S.

10.1101/2024.02.07.579252 — bioinformatics — Posted on 2024-02-10

3130 vSPACE: Exploring Virtual Spatial Representation of Articular Chondrocytes at the Single-Cell Level

Zhang, C.; Rowe, D.; Shin, D.-G.

10.1101/2024.02.07.577817 — bioinformatics — Posted on 2024-02-10

3131 Structural basis for the inhibition of PRC2 by active transcription histone posttranslational modifications

Cookis, T.; Lydecker, A.; Sauer, P. V.; Kasinath, V.; Nogales, E.

10.1101/2024.02.09.579730 — biochemistry — Posted on 2024-02-10

3132 Preferred left-handed conformations of glycyls with pathogenic variants protect against aggregation

Mishra, P.; Potlia, R.; Sandhu, K. S.

10.1101/2024.02.09.579738 — biochemistry — Posted on 2024-02-10

3133 Structural characterization of the ACDC domain from ApiAP2 proteins of the malaria parasite

Le Berre, M.; Tubiana, T.; Reutersward Waldner, P.; Lazar, N.; Gallay Li de la Sierra, I.; Santos, J. M.; Llinas, M.; Nessler, S.

10.1101/2024.02.09.579679 — biochemistry — Posted on 2024-02-10

3134 Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation

Sponholtz, M. R.; Byrne, P. O.; Lee, A. G.; Ramamohan, A. R.; Goldsmith, J. A.; McCool, R. S.; Zhou, L.; Johnson, N. V.; Hsieh, C.-L.; Connors, M.; Karthigeyan, K.; Campbell, J. D.; Permar, S. R.; Maynard, J. A.; Yu, D.; Bottomley, M. J.; McLellan, J. S.

10.1101/2024.02.10.579772 — molecular biology — Posted on 2024-02-10

3135 Androgens at the skin surface regulate S. aureus pathogenesis through the activation of agr quorum sensing

John, M. S.; Chinnappan, M.; Artami, M.; Bhattacharya, M.; Keogh, R.; Kavanaugh, J.; Sharma, T.; Horswill, A. R.; Harris-Tryon, T. A.

10.1101/2024.02.10.579753 — microbiology — Posted on 2024-02-10

3136 Comparative efficacy and safety of anti-cryptosporidial agents: An in vitro study on Nitazoxanide, HFL, KDU731, and Paromomycin against Cryptosporidium parvum

Whitta, S.; Lamont, B.; Suwanarusk, R.; Russell, B. M.; Muhsin-Sharafaldine, M.-R.

10.1101/2024.02.09.579383 — microbiology — Posted on 2024-02-10

3137 SHIP-1 differentially regulates IgE-induced IL-10 and antiviral responses in human monocytes

Solleti, S. K.; Matthews, B. E.; Rowe, R. K.

10.1101/2024.02.07.579109 — immunology — Posted on 2024-02-10

3138 The Primate-Specific Presence of Interferon Regulatory Factor-5 Pseudogene 1

Marquis, A.; Hubing, V.; Ziemann, C.; Moriyama, E. N.; Zhang, L.

10.1101/2024.02.07.579370 — immunology — Posted on 2024-02-10

3139 Temporal Dynamics of Cyanobacterial Bloom Community Composition and Toxin Production from Urban Lakes

Maurer, J. A.; Kim, A. M.; Oblie, N.; Hefferan, S.; Xie, H.; Slitt, A.; Jenkins, B. D.; Bertin, M. J.

10.1101/2024.02.07.579333 — pharmacology and toxicology — Posted on 2024-02-10

3140 Global genomic epidemiology of blaGES-5 carbapenemase-associated integrons

Matlock, W.; Shaw, L. P.; Stoesser, N.

10.1101/2024.02.09.579496 — genomics — Posted on 2024-02-10

3141 scGrapHiC: Deep learning-based graph deconvolution for Hi-C using single cell gene expression

Murtaza, G.; Butaney, B.; Wagner, J.; Singh, R.

10.1101/2024.02.07.579342 — genomics — Posted on 2024-02-10

3142 Determining susceptibility loci in triple negative breast cancer using a novel pre-clinical model

Simon, S. E.; Simmons, B. W.; Kim, M.; Joseph, S. C.; Korba, E.; Marathe, S. J.; Bohm, M. S.; Mahajan, S.; Bohl, C.; Read, R.; Holt, J.; Hayes, N.; Lu, L.; Williams, R.; Sipe, L.; Ashbrook, D. G.; Makowski, L.

10.1101/2024.02.08.579359 — genetics — Posted on 2024-02-10

3143 Marine phytoplankton and heterotrophic bacteria rapidly adapt to future pCO2 conditions in experimental co-cultures

Lu, Z.; Entwistle, E.; Kuhl, M. D.; Durrant, A. R.; Filho, M. M. B.; Goswami, A.; Morris, J.

10.1101/2024.02.07.579367 — evolutionary biology — Posted on 2024-02-10

3144 Advancing ecological networks: moving beyond binary classification to probabilistic interactions.

Philippe-Lesaffre, M.

10.1101/2024.02.07.579289 — ecology — Posted on 2024-02-10

3145 Impaired ovarian development in a zebrafish fmr1 knockout model

Rani, R.; Sri, N. S.; Medishetti, R.; Chatti, K.; Sevilimedu, A.

10.1101/2024.02.10.579749 — molecular biology — Posted on 2024-02-10

3146 Phylogenetic analysis of Mycobacterium bovis Reveals Evidence Of Animal And Zoonotic Tuberculosis Transmission Between Morocco And European Countries

Yahyaoui Azami, H.; Perea, C.; Stuber, T.; Bouslikhane, M.; Berrada, J.; Aboukhassib, H.; Allepuz Palau, A. O.; Reis, A. C.; Cunha, M. V.; Thacker, T. C.; Robbe-Austerman, S.; Salvador, L. C.; Quinn, F.

10.1101/2024.02.09.579592 — molecular biology — Posted on 2024-02-10

3147 Experimental assessment of marine microbial interactions: from predatory protists promoting bacterial survival to bacterial lysis of the protists

Axelsson-Olsson, D.; Gubonin, N.; Israelsson, S.; Pinhassi, J.

10.1101/2024.02.09.579682 — microbiology — Posted on 2024-02-10

3148 Comparative genomics illuminates adaptive evolution of DVNP with lifestyle and with loss of histone H1 in dinoflagellates

Wang, j.; Li, H.; Li, l.; Wang, y.; Lin, S.

10.1101/2024.02.09.579734 — microbiology — Posted on 2024-02-10

3149 Protective function and differentiation cues of brain-resident CD8+ T cells during immune surveillance of chronic latent Toxoplasma gondii infection

Porte, R.; Belloy, M.; Audibert, A.; Bassot, E.; Aida, A.; Alis, M.; Miranda-Capet, R.; Jourdes, A.; van Gisbergen, K. P.; Masson, F.; Blanchard, N.

10.1101/2024.02.08.579453 — immunology — Posted on 2024-02-10

3150 Structural insights into CXCR4 modulation and oligomerization

Saotome, K.; McGoldrick, L. L.; Ho, J.-H.; Ramlall, T. F.; Shah, S.; Moore, M. J.; Kim, J. H.; Leidich, R.; Olson, W. C.; Franklin, M. C.

10.1101/2024.02.09.579708 — biochemistry — Posted on 2024-02-10

3151 SARS-COV-2 induces blood-brain barrier and choroid plexus barrier impairments and vascular inflammation in mice

Qiao, H.; Deng, X.; Qiu, L.; Qu, Y.; Chiu, Y.; Chen, F.; Xia, S.; Muenzel, C.; Ge, T.; Song, P.; Bonnin, A.; Zhao, Z.; Yuan, W.

10.1101/2024.02.09.579589 — neuroscience — Posted on 2024-02-10

3152 CoCoPyE: feature engineering for learning and prediction of genome quality indices

Birth, N.; Leppich, N.; Schirmacher, J.; Andreae, N.; Steinkamp, R.; Blanke, M.; Meinicke, P.

10.1101/2024.02.07.579156 — bioinformatics — Posted on 2024-02-10

3153 Larval protein restriction interacts with adult diet to increase fitness in an outbred multiparent population.

Jones, A.; Donnell, D.; King, E. G.; Ng'oma, E.

10.1101/2024.02.10.579751 — developmental biology — Posted on 2024-02-10

3154 scSpatialSIM: a simulator of spatial single-cell molecular data

Soupir, A. C.; Wrobel, J.; Creed, J. H.; Ospina, O. E.; Wilson, C. M.; Manley, B. J.; Peres, L. C.; Fridley, B. L.

10.1101/2024.02.08.579486 — cell biology — Posted on 2024-02-10

3155 A lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence

Orr, J. C.; Laali, A.; Durrenberger, P. F.; Lazarus, K. A.; El Mdawar, M.-B.; Janes, S. M.; Hynds, R. E.

10.1101/2024.02.09.579635 — cell biology — Posted on 2024-02-10

3156 Clearance of protein aggregates during cell division

Du, S.; Wang, Y.; Chen, B.; Xie, S.; Chan, K. Y.; Hay, D. C.; Chew, T. G.

10.1101/2024.02.10.579754 — cell biology — Posted on 2024-02-10

3157 Selective Translation Orchestrates Key Signaling Pathways in Primed Pluripotency

Okubo, C.; Nakamura, M.; Sato, M.; Shichino, Y.; Mito, M.; Takashima, Y.; Iwasaki, S.; Takahashi, K.

10.1101/2024.02.09.579580 — cell biology — Posted on 2024-02-10

3158 Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in SCN8A Epileptic Encephalopathy

Miralles, R. M.; Boscia, A. R.; Kittur, S.; Vundela, S. R.; Wengert, E. R.; Patel, M. K.

10.1101/2024.02.09.579511 — neuroscience — Posted on 2024-02-10

3159 Gene regulatory network landscape of Group 3/4 medulloblastoma

Joshi, P.; Stelzer, T.; Okonechnikov, K.; Sarropoulos, I.; Sepp, M.; Pour-Jamnani, M. V.; Rademacher, A.; Yamada-Saito, T.; Schneider, C.; Schmidt, J.; Schaefer, P.; Leiss, K.; Bortolomeazzi, M.; Mallm, J.-P.; da Silva, P. B. G.; Statz, B.; Wittmann, A.; Schramm, K.; Blattner-Johnson, M.; Fiesel, P.; Jones, B.; Milde, T.; Pajtler, K.; van Tilburg, C. M.; Witt, O.; Rippe, K.; Korshunov, A.; Jones, D. T. W.; Hovestadt, V.; Northcott, P. A.; Thongjuea, S.; Jaeger, N.; Kaessmann, H.; Pfister, S. M.; Kutscher, L. M.

10.1101/2024.02.09.579680 — cancer biology — Posted on 2024-02-10

3160 Loss of UBE3A impacts both neuronal and non-neuronal cells in human cerebral organoids

Estridge, R. C.; Yagci, Z. B.; Sen, D.; Ptacek, T. S.; Simon, J. M.; Keung, A. J.

10.1101/2024.02.09.579672 — developmental biology — Posted on 2024-02-10

3161 Enhancing Portability of Trans-Ancestral Polygenic Risk Scores through Tissue-Specific Functional Genomic Data Integration

Crone, B.; Boyle, A. P.

10.1101/2024.02.07.579365 — genetics — Posted on 2024-02-09

3162 Defense systems and horizontal gene transfer in bacteria

Kogay, R.; Wolf, Y. I.; Koonin, E. V.

10.1101/2024.02.09.579689 — evolutionary biology — Posted on 2024-02-09

3163 Variability of immune gene expression among different groups within ant colonies shows a multifaceted response to infection by a non-lethal ectoparasitic fungus

Orban-Bakk, K.; Schultner, E.; Heinze, J.; Marko, B.; Csata, E.

10.1101/2024.02.08.579503 — zoology — Posted on 2024-02-09

3164 Effective lowering of α-synuclein expression by targeting G-quadruplex structures within the SNCA genome

Pirota, V.; Rey, F.; Fantini, V.; Esposito, L.; Pandini, C.; Di Gerlando, R.; Doria, F.; Mella, M.; Pansarasa, O.; Gandellini, P.; Freccero, M.; Carelli, S.; Cereda, C.

10.1101/2024.02.09.579657 — molecular biology — Posted on 2024-02-09

3165 Karyotype Description and Comparative Chromosomal Mapping of 5S rDNA in 21 species

Luo, X.; Liu, Y.; Gong, X.; Ye, M.; Xiao, Q.; Zhen, Z.

10.1101/2024.02.08.579556 — molecular biology — Posted on 2024-02-09

3166 Internal structure of Mycoplasma mobile gliding machinery analyzed by negative staining electron tomography

Fukushima, M.; Toyonaga, T.; Tahara, Y. O.; Nakane, D.; Miyata, M.

10.1101/2024.02.08.578511 — microbiology — Posted on 2024-02-09

3167 Fourfold increase in photocurrent generation of Synechocystis sp. PCC 6803 by exopolysaccharide deprivation

Wey, L. T.; Wroe, E.; Sadilek, V.; Shang, L.; Chen, X.; Zhang, J.; Howe, C. J.

10.1101/2024.02.09.579478 — microbiology — Posted on 2024-02-09

3168 Characterization of Neisseria gonorrhoeae colonization of macrophages under distinct polarization states and nutrients environment

Juarez Rodriguez, M. D.; Marquette, M.; Youngblood, R.; Dhungel, N.; Torres Escobar, A.; Ivanov, S. S.; Dragoi, A.-M.

10.1101/2024.02.08.579566 — microbiology — Posted on 2024-02-09

3169 Prevalent human gut Enterocloster spp. produce urolithin A from its dietary precursor using a molybdenum-dependent dehydroxylase

Pidgeon, R.; Mitchell, S.; Shamash, M.; Suleiman, L.; Dridi, L.; Maurice, C. F.; Castagner, B.

10.1101/2024.02.08.579493 — microbiology — Posted on 2024-02-09

3170 Similar mechanisms of retron-mediated anti-phage defense for different families of tailed phages

Toro, N.; Garcia-Rodriguez, F. M.; Martinez Abarca, F.; Wilkinson, M. E.

10.1101/2024.02.09.579579 — microbiology — Posted on 2024-02-09

3171 Global neural encoding of model-free and inference-based strategies in mice

Wang, S.; Gao, H.; Ishizu, K.; Funamizu, A.

10.1101/2024.02.08.579559 — neuroscience — Posted on 2024-02-09

3172 Focused ultrasound increases gene delivery to deep brain structure following the administration of a recombinant adeno-associated virus in the cerebrospinal fluid

Kofoed, R. H.; Noseworthy, K.; Wu, K.; Vecchio, L. M.; Dibia, C. L.; Sivadas, S.; Wu, S.-K.; Mikloska, K.; White, M.; Elmer, B.; Ramachandran, S.; Mueller, C.; Hynynen, K.; Aubert, I.

10.1101/2024.02.09.579587 — neuroscience — Posted on 2024-02-09

3173 Functional genomic screening in Komagataella phaffii enabled by high-activity CRISPR-Cas9 library

Tafrishi, A.; Trivedi, V.; Xing, Z.; Li, M.; Mewalal, R.; Cutler, S.; Blaby, I.; Wheeldon, I.

10.1101/2024.02.08.579509 — systems biology — Posted on 2024-02-09

3174 Self-assembled cell-scale containers made from DNA origami membranes

Karfusehr, C.; Eder, M.; Simmel, F. C.

10.1101/2024.02.09.579479 — synthetic biology — Posted on 2024-02-09

3175 Heat Conduction Simulation of Chondrocyte-Embedded Agarose Gels Suggests Negligible Impact of Viscoelastic Dissipation on Temperature Change

Myers, E.; Piazza, M.; Owkes, M.; June, R. K.

10.1101/2024.02.08.579524 — bioengineering — Posted on 2024-02-09

3176 Olive mill solid waste induces beneficial mushroom-specialized metabolite diversity: a computational metabolomics study.

Khatib, S.; Pereman, I.; Kostanda, E.; Zdouc, M. M.; Ezov, N.; Schweitzer, R.; van der Hooft, J. J. J.

10.1101/2024.02.09.579616 — biochemistry — Posted on 2024-02-09

3177 Lung Mycobacterium tuberculosis infection perturbs metabolic pathways in non-pulmonary tissues

Pahwa, F.; Chaudhary, S.; Dayal, A.; Nanda, R.

10.1101/2024.02.09.579656 — biochemistry — Posted on 2024-02-09

3178 Ungulate substrate selection in fauna passages

Helldin, J. O.; Niemi, M.

10.1101/2024.02.08.579517 — animal behavior and cognition — Posted on 2024-02-09

3179 Single-molecule observations of human small heat shock proteins in complex with aggregation-prone client proteins

Rice, L. J.; Marzano, N. R.; Cox, D.; van Oijen, A. M.; Ecroyd, H.

10.1101/2024.02.08.579576 — molecular biology — Posted on 2024-02-09

3180 Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses

Fernandez, I.; Bontems, F.; Brun, D.; Coquin, Y.; Goverde, C. A.; Correia, B. E.; Gessain, A.; Buseyne, F.; Rey, F. A.; Backovic, M.

10.1101/2024.02.09.579661 — microbiology — Posted on 2024-02-09

3181 Antiviral effect of betacyanins from red pitahaya (Hylocereus polyrhizus) against influenza A virus

Lim, C. M.; Lal, S. K.; Mat Isa, N.; Omar, A. R.; Choo, W. S.

10.1101/2024.02.09.579603 — microbiology — Posted on 2024-02-09

3182 Identification of echinacoside as a tobramycin potentiator against Pseudomonas aeruginosa aggregates

Cai, Y.-M.; Crabbe, A.; Coenye, T.

10.1101/2024.02.09.579617 — microbiology — Posted on 2024-02-09

3183 Cryo-EM structure of a conjugative T4SS identifies a molecular switch regulating pilus biogenesis

Waksman, G.; MACE, K.

10.1101/2024.02.08.579498 — microbiology — Posted on 2024-02-09

3184 Serological screening in animals combined with environmental surveys provides definite proof of the local establishment of Burkholderia pseudomallei in Guadeloupe

Gasque, M.; Guernier-Cambert, V.; Manuel, G.; Aaziz, R.; Terret, J.; Deshayes, T.; Baudrimont, X.; Breurec, S.; Rochelle-Newall, E.; Laroucau, K.

10.1101/2024.02.09.579440 — microbiology — Posted on 2024-02-09

3185 Low frequency stimulation for seizure suppression: identification of optimal targets in the entorhinal-hippocampal circuit

Kleis, P.; Paschen, E.; Haeussler, U.; Haas, C. A.

10.1101/2024.02.09.579614 — neuroscience — Posted on 2024-02-09

3186 Weight illusions explained by efficient coding based on correlated natural statistics

Bays, P.

10.1101/2024.02.09.579650 — neuroscience — Posted on 2024-02-09

3187 Brain signal complexity and aperiodicity predict human corticospinal excitability

Frohlich, J.; Ruch, S.; Trunk, B. H.; Keute, M.; Mediano, P. A. M.; Gharabaghi, A.

10.1101/2024.02.09.579457 — neuroscience — Posted on 2024-02-09

3188 The Memorability of Voices is Predictable and Consistent across Listeners

Revsine, C.; Goldberg, E.; Bainbridge, W. A.

10.1101/2024.02.08.579540 — neuroscience — Posted on 2024-02-09

3189 Integrative single-cell analysis of neural stem/progenitor cells reveals epigenetically dysregulated interferon response in progressive multiple sclerosis

10.1101/2024.02.09.579648 — neuroscience — Posted on 2024-02-09

3190 Fine-grained neural coding of bodies and body parts in human visual cortex

Garcia Ramirez, J.; Vanhoyland, M.; Apurva Murty, R. N.; Decramer, T.; Van Paesschen, W.; Bracci, S.; Op de Beeck, H.; Kanwisher, N. G.; Janssen, P.; Theys, T.

10.1101/2024.02.09.579107 — neuroscience — Posted on 2024-02-09

3191 Innate floral object identification in the generalist solitary hoverfly pollinator Eristalinus aeneus

Mishra, A.; Jain, A.; Iyer, P. S.; Suryanarayanan, A.; Nordstrom, K.; Olsson, S. B.

10.1101/2024.02.08.579518 — animal behavior and cognition — Posted on 2024-02-09

3192 A paternal cardiac lesion induces cardiac adaptation in offspring

Coppe, B.; Galardi-Castilla, M.; Sanz-Morejon, A.; Arora, P.; Lucas, J.; Lalaguna, L.; Lara Pezzi, E.; Flores, I.; Mercader, N.

10.1101/2024.02.09.579452 — developmental biology — Posted on 2024-02-09

3193 Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury

Odell, E. P.; Jabassini, N.; Schniedewind, B.; Pease-Raissi, S. E.; Frymoyer, A.; Christians, U.; Green, A. J.; Chan, J. R.; Ostrem, B. E. L.

10.1101/2024.02.08.578953 — neuroscience — Posted on 2024-02-09

3194 Upregulation of the Proto-Oncogene Src Kinase in Alzheimer's Disease: From Molecular Interactions to Therapeutic Potential

Mastroeni, D.; Chan, C. K.; Morshed, N.; Diouf, D.; de Avila, C.; Suazo, C.; Nolz, J.; Lopatin, U.; Wang, Q.; Serrano, G.; Beach, T.; Dunkley, T.; Jensen, K.; Van Den Hove, D.; White, F. M.; Chiu, P.-L.; Singharoy, A.; Reiman, E. M.; Readhead, B. P.

10.1101/2024.02.07.579336 — neuroscience — Posted on 2024-02-09

3195 ChineseEEG: A Chinese Linguistic Corpora EEG Dataset for Semantic Alignment and Neural Decoding

Mou, X.; He, C.; Tan, L.; Yu, J.; Liang, H.; Zhang, J.; Tian, Y.; Yang, Y.; Xu, T.; Wang, Q.; Cao, M.; Chen, Z.; Hu, C.; Wang, X.; Liu, Q.; Wu, H.

10.1101/2024.02.08.579481 — neuroscience — Posted on 2024-02-09

3196 Resource or slot model in visual working memory: Are they different?

Hojjati, F.; Motahharynia, A.; Adibi, A.; Adibi, I.; Sanayei, M.

10.1101/2024.02.08.579494 — neuroscience — Posted on 2024-02-09

3197 Dynamics of White Matter Architecture in Lexical Production among Middle-Aged Adults

Guichet, C.; Roger, E.; Attye, A.; Achard, S.; Mermillod, M.; Baciu, M.

10.1101/2024.02.09.579645 — neuroscience — Posted on 2024-02-09

3198 The role of cortistatin in neuroimmune dysregulation underlying ischemic stroke

Castillo-Gonzalez, J.; Buscemi, L.; Vargas-Rodriguez, P.; Serrano-Martinez, I.; Forte-Lago, I.; Price-Hirt, M.; Hernandez-Cortes, P.; Hirt, L.; Gonzalez-Rey, E.

10.1101/2024.02.07.579281 — immunology — Posted on 2024-02-09

3199 ABCC10 roles in plant development and the transport of indole-3-butyric acid

Homayouni, A.; Damodaran, S.; Schreiber, K.; Michniewicz, M.; Gunther, L.; Strader, L. C.

10.1101/2024.02.07.579300 — plant biology — Posted on 2024-02-09

3200 Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs

Risen, S.; Kusick, B.; Sharma, S.; Gilberto, V.; Brindley, S.; Aguilar, M.; Brown, J.; McGrath, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.

10.1101/2024.02.07.579323 — pharmacology and toxicology — Posted on 2024-02-09

3201 The Xanthomonas fragariae effector XopK suppresses stomatal immunity by perturbing abscisic acid signaling in strawberry

Feng, J.; Cai, X.; Zhang, W.; Yu, H.; Wen, Y.-Q.

10.1101/2024.02.07.579334 — pathology — Posted on 2024-02-09

3202 Ligand-induced conformational changes in the β1-Adrenergic Receptor Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry

Toporowska, J.; Kapoor, P.; Musgaard, M.; Gherbi, K.; Sengmany, K.; Qu, F.; Soave, M.; Yen, H.-Y.; Hansen, K.; Jazayeri, A.; Hopper, J. T. S.; Politis, A.

10.1101/2024.02.07.579309 — biophysics — Posted on 2024-02-09

3203 In Vivo Plasmonic Enhancement of the Photocycle Dynamics and Fluorescence of Genetically Encoded Voltage Indicators

Locarno, M.; Dong, Q.; Meng, X.; Glessi, C.; Hettema, N.; Brandsma, N.; Blokhuizen, S.; Castaneda, A.; Schmidt, T.; Ganapathy, S.; Post, M.; van Roemburg, L.; Xu, B.; Cho, C.-T.; Laan, L.; Chien, M.-P.; Brinks, D.

10.1101/2024.02.07.579195 — biophysics — Posted on 2024-02-09

3204 A single giant cell at the origin of an evolutionary innovation

Badiane, A.; Viala, S.; Armisen, D.; Mignerey, I.; Forcet-Vauchel, C.; De Jesus Villanueva, C. N.; Van Belleghem, S.; Crumiere, A.; Santos, E.; Francesconi, M.; Khila, A.

10.1101/2024.02.08.579433 — evolutionary biology — Posted on 2024-02-09

3205 The intensity of supplementary feeding in an urban environment impacts overwintering Mallards Anas platyrchynhos as wintering conditions get harsher

Witkowska, M.; Wesolowski, W.; Martyna Markiewicz, ; Jonasz Pakizer, ; Julia Neumann, ; Ozarowska, A.; Meissner, W.

10.1101/2024.02.07.579312 — ecology — Posted on 2024-02-09

3206 Effects of satellite-linked telemetry tags on humpback whales in the Gulf of Maine: photographic assessment of tag sites

Gulland, F. M. D.; Robbins, J.; Zerbini, A. N.; Andrews-Goff, V.; Berube, M.; Clapham, P. J.; Double, M.; Gales, N.; Kennedy, A. S.; Landry, S.; Mattila, D. K.; Sandilands, D.; Tackaberry, J. E.; Uhart, M. M.; Vanstreels, R. E. T.

10.1101/2024.02.07.579298 — ecology — Posted on 2024-02-09

3207 Systematic Analysis of Immune Changes after B-cell Depletion in Autoimmune Multiple Sclerosis

Wei, J.; Moon, J.; Yasumizu, Y.; Zhang, L.; Radassi, K.; Buitrago-Pocasangre, N.; Deerhake, M. E.; Strauli, N.; Chan, A.; Herman, A.; Pedotte, R.; Raposo, C.; Tackenberg, B.; Yim, I.; Pappalardo, J.; Longbrake, E. E.; Sumida, T. S.; Axisa, P.-P.; Hafler, D. A.

10.1101/2024.02.07.576204 — immunology — Posted on 2024-02-09

3208 Adapting to loss: A normative account of grief

Dulberg, Z.; Dubey, R.; Cohen, J. D.

10.1101/2024.02.06.578702 — neuroscience — Posted on 2024-02-09

3209 Does amplitude compression help or hinder attentional neural speech tracking?

Orf, M.; Hannemann, R.; Obleser, J.

10.1101/2024.02.07.578931 — neuroscience — Posted on 2024-02-09

3210 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles

Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.

10.1101/2024.02.07.578591 — biophysics — Posted on 2024-02-09

3211 Modified histone peptides uniquely tune the material properties of HP1α condensates.

Deshpande, P.; Prentice, E.; Vidal Ceballos, A.; Casaccia, P.; Elbaum-Garfinkle, S.

10.1101/2024.02.07.579285 — biophysics — Posted on 2024-02-09

3212 Interpretable Drug Response Prediction through Molecule Structure-aware and Knowledge-Guided Visible Neural Network

Xie, J.; Zhang, Z.; Li, Y.; Rao, J.; Yang, Y.

10.1101/2024.02.07.579280 — bioinformatics — Posted on 2024-02-09

3213 Considerations for reporting variants in novel candidate genes identified during clinical genomic testing

10.1101/2024.02.05.579012 — genetics — Posted on 2024-02-09

3214 Genome-wide analysis of flavonoid biosynthetic genes in Musaceae (Ensete, Musella, and Musa species) reveals amplification of flavonoid 3',5'-hydroxylase

Cui, D.; Xiong, G.; Ye, L.; Gornall, R.; Wang, Z.; Heslop-Harrison, J.; Liu, Q.

10.1101/2024.02.08.579575 — genetics — Posted on 2024-02-09

3215 A genome wide search for non-additive allele effects identifies PSKH2 as involved in the variability of Factor V activity.

Gendre, B.; Martinez-Perez, A.; Kleber, M. E.; van Hylckama Vlieg, A.; Boland, A.; Olaso, R.; Germain, M.; Munsch, G.; Moissl, A. P.; Suchon, P.; Souto, J. C.; Soria Fernandez, J. m.; Deleuze, J.-F.; Marz, W.; Rosendaal, F.; Sabater-Lleal, M.; Morange, P. E.; Tregouet, D.-A.

10.1101/2024.02.08.579474 — genetics — Posted on 2024-02-09

3216 First evidence for the evolution of host manipulation by tumors during the long-term vertical transmission of tumor cells in Hydra oligactis

BOUTRY, J.; Oceane, R.; Lena, G.; Jordan, M.; Aurora, N.; Sophie, T.; Beata, U.; Rodrigo, H.; Antoine, D. M.; Jacint, T.; Frederic, T.

10.1101/2024.02.08.579507 — evolutionary biology — Posted on 2024-02-09

3217 American Crow responses to habitat desaturation by West Nile virus

Caffrey, C.

10.1101/2024.02.01.578463 — ecology — Posted on 2024-02-09

3218 Differential mitochondrial bioenergetics and cellular resilience in astrocytes, hepatocytes, and fibroblasts from aging baboons

Adekunbi, D. A.; Huber, H. F.; Li, C.; Cox, L. A.; Nathanielsz, P. W.; Salmon, A. B.

10.1101/2024.02.06.579010 — cell biology — Posted on 2024-02-09

3219 Viral delivery of compact CRISPR-Cas12f for in vivo gene editing applications

Sharrar, A.; Meacham, Z.; Staples-Ager, J.; Arake de Tacca, L.; Rabuka, D.; Collingwood, T.; Schelle, M.

10.1101/2024.02.06.578965 — molecular biology — Posted on 2024-02-09

3220 PP2A catalytic subunit alpha is critically required for CD8+ T cell homeostasis and anti-bacterial responses

Zeng, H.; Zhou, X.; Li, M.; Ai, M.; Li, Y.; Zhu, X.; Hansen, M. J.; Zhong, J.; Johnson, K. L.; Zenka, R.; Pandey, A.; Pease, L. R.

10.1101/2024.02.06.578745 — immunology — Posted on 2024-02-09

3221 From connectome to effectome: learning the causal interaction map of the fly brain

Pospisil, D. A.; Aragon, M. J.; Dorkenwald, S.; Matsliah, A.; Sterling, A. R.; Schlegel, P.; Yu, S.-c.; McKellar, C. M.; Costa, M.; Eichler, K.; Jefferis, G. S. X. E.; Murthy, M.; Pillow, J. W.

10.1101/2023.10.31.564922 — neuroscience — Posted on 2024-02-09

3222 Unfolded Von Willebrand Factor Binds Protein S and Reduces Anticoagulant Activity

Sim, M. M. S.; Mollica, M. Y.; Alfar, H. R.; Hollifield, M.; Chung, D. W.; Fu, X.; Gandhapudi, S.; Coenen, D. M.; Prakhya, K. S.; Mahmood, D. F. D.; Banerjee, M.; Peng, C.; Li, X.; Thornton, A. C.; Porterfield, J. Z.; Sturgill, J. L.; Sievert, G. A.; Barton-Baxter, M.; Zheng, Z.; Campbell, K. S.; Woodward, J. G.; Lopez, J. A.; Whiteheart, S. W.; Garvy, B. A.; Wood, J. P.

10.1101/2024.02.08.579463 — biochemistry — Posted on 2024-02-09

3223 Differential tissue deformability underlies shape divergence of the embryonic brain and spinal cord under fluid pressure

McLaren, S. B. P.; Xue, S.-L.; Ding, S.; Winkel, A.; Baldwin, O.; Dwarakacherla, S.; Franze, K.; Hannezo, E.; Xiong, F.

10.1101/2024.01.12.575349 — developmental biology — Posted on 2024-02-09

3224 Convergent within-host evolution alters key virulence factors in a Klebsiella pneumoniae clone during a large hospital outbreak

Zaborskyte, G.; Hjort, K.; Lytsy, B.; Sandegren, L.

10.1101/2024.02.06.577356 — microbiology — Posted on 2024-02-09

3225 Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86/JN.1 lineages combining increased fitness and antibody evasion

Planas, D.; Staropoli, I.; Michel, V.; Lemoine, F.; Donati, F.; Prot, M.; Porrot, F.; Benhassine, F. G.; Jeyarajah, B.; Brisebarre, A.; Dehan, O.; Avon, L.; Bolland, W.; Hubert, M.; Buchreiser, J.; Vanhoucke, T.; Rosenbaum, P.; Veyer, D.; Pere, H.; Lina, B.; Assant, S. T.; Hocqueloux, L.; Prazuck, T.; Loriere, E. S.; Schwartz, O.

10.1101/2023.11.20.567873 — microbiology — Posted on 2024-02-09

3226 Forecasting dominance of SARS-CoV-2 lineages by anomaly detection using deep AutoEncoders

Rancati, S.; Nicora, G.; Prosperi, M.; Bellazzi, R.; Marini, S.; Salemi, M.

10.1101/2023.10.24.563721 — bioinformatics — Posted on 2024-02-09

3227 Drosophila HCN mediates gustatory homeostasis by preserving sensillar transepithelial potential in sweet environments

Lee, M.; Park, S. H.; Joo, K. M.; Kwon, J. Y.; Lee, K.-H.; Kang, K.

10.1101/2024.02.06.579099 — neuroscience — Posted on 2024-02-09

3228 Loss of function in RBBP5 results in a syndromic neurodevelopmental disorder associated with microcephaly

Huang, Y.; Jay, K. L.; Huang, A. Y.-W.; Wan, J.; Jangam, S. V.; Chorin, O.; Rothschild, A.; Barel, O.; Mariani, M.; Xue, H.; Huang, J.; Iascone, M.; Mignot, C.; Undiagnosed Diseases Network, ; Keren, B.; Saillour, V.; Mah-Som, A. Y.; Sacharow, S.; Rajabi, F.; Costin, C.; Yamamoto, S.; Kanca, O.; Bellen, H. J.; Rosenfeld, J. A.; Palmer, C. G.; Nelson, S.; Wangler, M. F.; Martinez-Agosto, J. A.

10.1101/2024.02.06.578086 — genetics — Posted on 2024-02-09

3229 Data-driven analyses of social complexity in bees reveal phenotypic diversification following a major evolutionary transition

Peled, O.; Greenbaum, G.; Bloch, G.

10.1101/2024.02.09.579609 — evolutionary biology — Posted on 2024-02-09

3230 Emergent collective alignment gives competitive advantage to longer cells during range expansion

van den Berg, N.; Thijssen, K.; Nguyen, T. T.; Sarlet, A.; Cordero, M.; Vazquez, A. G.; Mitarai, N.; Doostmohammadi, A.; Jauffred, L.

10.1101/2024.01.26.577059 — biophysics — Posted on 2024-02-09

3231 Varying the position of phospholipid acyl chain unsaturation modulates hopanoid and sterol ordering

Nguyen, A. H. N.; Sharp, L.; Lyman, E.; Saenz, J. P.

10.1101/2023.09.06.556521 — biophysics — Posted on 2024-02-09

3232 Deciphering the Genetic Code of Neuronal Type Connectivity: A Bilinear Modeling Approach

Qiao, M.

10.1101/2023.08.01.551532 — neuroscience — Posted on 2024-02-09

3233 The neurohormone tyramine stimulates the secretion of an Insulin-Like Peptide from the intestine to modulate the systemic stress response in C. elegans

Veuthey, T.; Giunti, S.; De Rosa, M. J.; Alkema, M. J.; Rayes, D.

10.1101/2024.02.06.579207 — neuroscience — Posted on 2024-02-09

3234 LSD Modulates Proteins Involved in Cell Proteostasis, Energy Metabolism and Neuroplasticity in Human Brain Organoids

Costa, M. d. N.; Goto-Silva, L.; Nascimento, J. M.; Domith, I.; Karmirian, K.; Feilding, A.; Trindade, P.; Martins-de-Souza, D.; Rehen, S. K.

10.1101/2024.01.30.577659 — neuroscience — Posted on 2024-02-09

3235 AttentionPert: Accurately Modeling Multiplexed Genetic Perturbations with Multi-scale Effects

Bai, D.; Ellington, C.; Mo, S.; Song, L.; Xing, E.

10.1101/2024.02.02.578656 — bioinformatics — Posted on 2024-02-09

3236 Improving generalizability for MHC-I binding peptide predictions through geometric deep learning

Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Renaud, N.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.

10.1101/2023.12.04.569776 — bioinformatics — Posted on 2024-02-09

3237 MolLM: A Unified Language Model for Integrating Biomedical Text with 2D and 3D Molecular Representations

Tang, X.; Tran, A.; Tan, J.; Gerstein, M.

10.1101/2023.11.25.568656 — bioinformatics — Posted on 2024-02-09

3238 Higher-order combinatorial chromatin perturbations by engineered CRISPR-Cas12a for functional genomics

Hsiung, C. C.- S.; Wilson, C. M.; Sambold, N. A.; Dai, R.; Chen, Q.; Misiukiewicz, S.; Arab, A.; Teyssier, N.; O'Loughlin, T.; Cofsky, J.; Shi, J.; Gilbert, L. A.

10.1101/2023.09.18.558350 — genetics — Posted on 2024-02-09

3239 Brain enlargement with rostral bias in larvae from a spontaneously occurring female variant line of Xenopus; role of aberrant embryonic Wnt/β-catenin signaling

Okamoto, H.; Hongo, I.; Yamaguchi, C.

10.1101/2023.10.23.563695 — developmental biology — Posted on 2024-02-09

3240 Setdb1 safeguards genome integrity in muscle stem cells to allow for regenerative myogenesis and inflammation

Garcia, P.; Jarassier, W.; Brun, C.; Giordani, L.; Agostini, F.; Kung, W. H.; Peccate, C.; Ravent, J.; Fall, S.; Petit, V.; Cheung, T.; Ait-Si-Ali, S.; Le Grand, F.

10.1101/2023.06.08.544190 — cell biology — Posted on 2024-02-09

3241 S-nitrosylation of EZH2 at C329 and C700 interplay with PRC2 complex assembly, methyltransferase activity, and EZH2 stability to regulate endothelial functions

Sakhuja, A.; Katakia, Y. T.; Tripathi, S. M.; Bhattacharya, R.; Thakkar, N. P.; Ramakrishnan, S.; Chakraborty, S.; Thakar, S.; Sundriyal, S.; Chowdhury, S.; Majumder, S.

10.1101/2024.02.06.579117 — cell biology — Posted on 2024-02-09

3242 Disentangling abiotic and biotic effects of treated wastewater on stream biofilm resistomes enables the discovery of a new planctomycete beta-lactamase

Attrah, M.; Schaerer, M. R.; Esposito, M.; Gionchetta, G.; Buergmann, H.; Lens, P. N. L.; Fenner, K.; van de Vossenberg, J.; Robinson, S. L.

10.1101/2023.11.20.567610 — microbiology — Posted on 2024-02-09

3243 Specific interaction between Group B Streptococcus CC17 hypervirulent clone and phagocytes

Bourrel, A.-S.; Picart, A.; Fernandez, J.-C.; Hays, C.; Saubamea, B.; Mignon, V.; Poyart, C.; Tazi, A.; Guignot, J.

10.1101/2022.12.02.518834 — microbiology — Posted on 2024-02-09

3244 Glial expression of Drosophila UBE3A causes spontaneous seizures modulated by 5-HT signaling

Sleep, M.; Landaverde, S.; Lacoste, A.; Tan, S.; Schuback, R.; Reiter, L.; Iyengar, A.

10.1101/2024.02.08.579543 — neuroscience — Posted on 2024-02-09

3245 Peripheral insulin resistance attenuates cerebral glucose metabolism and impairs working memory in healthy adults

Deery, H.; Liang, E.; Di Paolo, R. A.; Voigt, K.; Murray, G.; Siddiqui, N.; Moran, C.; Egan, G.; Jamadar, S. D.

10.1101/2023.09.08.556948 — neuroscience — Posted on 2024-02-09

3246 Resting state aperiodic exponent predicts Research Domain Criteria Social Processes in young typically developing adults

Ford, T. C.; Hill, A. T.; Parrella, N.-F.; Kirkovski, M.; Donaldson, P.; Enticott, P. G.

10.1101/2023.09.19.558536 — neuroscience — Posted on 2024-02-09

3247 Species-conserved mechanisms of abstract rule learning promote cognitive flexibility in complex environments

Baehner, F.; Popov, T.; Boehme, N.; Hermann, S.; Merten, T.; Zingone, H.; Koppe, G.; Meyer-Lindenberg, A.; Toutounji, H.; Durstewitz, D.

10.1101/2022.11.14.516439 — neuroscience — Posted on 2024-02-09

3248 MHC class II transactivator effects on local and systemic immune responses in an α-synuclein seeded rat model for Parkinson's disease

Fredlund, F.; Jimenez-Ferrer, I.; Grabert, K.; Belfiori, L.; Luk, K.; Swanberg, M.

10.1101/2022.12.02.518821 — neuroscience — Posted on 2024-02-09

3249 Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy

Wahl, D.; Risen, S. J.; Osburn, S. C.; Emge, T.; Sharma, S.; Gilberto, V. S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.; LaRocca, T. J.

10.1101/2024.02.03.578493 — physiology — Posted on 2024-02-09

3250 scDirect: key transcription factor identification for directing cell state transitions based on single-cell multi-omics data

Li, C.; Chen, S.; Chen, Y.; Bian, H.; Hao, M.; Wei, L.; Zhang, X.

10.1101/2024.01.08.574757 — bioinformatics — Posted on 2024-02-09

3251 GEMCAT - A new algorithm for gene expression-based prediction of metabolic alterations

Sharma, S.; Sauter, R.; Hotze, M.; Prowatke, A. M. P.; Niere, M.; Kipura, T.; Egger, A.-S.; Thedieck, K.; Kwiatkowski, M.; Ziegler, M.; Heiland, I.

10.1101/2024.01.15.575710 — bioinformatics — Posted on 2024-02-09

3252 Deep learning-based proteomics enables accurate classification of bulk and single-cell samples

Krull, K. K.; Kuehn, A.; Hoehn, J.; Brinker, T. J.; Krijgsveld, J.

10.1101/2024.02.03.578734 — bioinformatics — Posted on 2024-02-09

3253 Contextualising samples: Supporting reference genomes of European biodiversity through sample and associated metadata collection

Boehne, A.; Fernandez, R.; Leonard, J. A.; McCartney, A. M.; McTaggart, S.; Melo-Ferreira, J.; Monteiro, R.; Oomen, R. A.; Vinnere Pettersson, O.; Struck, T. H.

10.1101/2023.06.28.546652 — genomics — Posted on 2024-02-09

3254 Cost-effectiveness of Precision Guided SIT for Control of Anopheles gambiae in the Upper River Region, The Gambia.

Gendron, W. A. C.; Raban, R.; Mondal, A.; Sanchez C., H. M.; Smidler, A.; Zilberman, D.; Ilboudo, P. G.; D'Alessandro, U.; Marshall, J. M.; Akbari, O. S.

10.1101/2023.07.20.549762 — genetics — Posted on 2024-02-09

3255 Associations between common genetic variants and income provide insights about the socioeconomic health gradient

Kweon, H.; Burik, C. A. P.; Ning, Y.; Ahlskog, R.; Xia, C.; Abner, E.; Bao, Y.; Bhatta, L.; Faquih, T.; Feijter, M.; Fisher, P.; Gelemanovic, A.; Giannelis, A.; Hottenga, J.-J.; Khalili, B.; Lee, Y.; Li-Gao, R.; Masso, J.; Myhre, R.; Palviainen, T.; Rietveld, C. A. P.; Teumer, A.; Verweij, R. M.; Willoughby, E. A.; Agerbo, E.; Bergmann, S.; Boomsma, D. I.; Borglum, A. D.; Brumpton, B. M.; Davies, N. M.; Esko, T.; Gordon, S. D.; Homuth, G.; Ikram, A.; Johannesson, M.; Kaprio, J.; Kidd, M. P.; Kutalik, Z.; Kwong, A. S. F.; Lee, J.; Luik, A.; Mook-Kanamori, D. O.; Magnus, P.; Marques-Vidal, P.; M

10.1101/2024.01.09.574865 — genetics — Posted on 2024-02-09

3256 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2024-02-09

3257 Novel reassortments of variation underlie repeated adaptation to whole genome duplication in two outcrossing Arabidopsis species

Bohutinska, M.; Petrikova, E.; Booker, T. R.; Vives Cobo, C.; Vlcek, J.; Sramkova, G.; Postulkova, A.; Hojka, J.; Marhold, K.; Kolar, F.; Yant, L.; Schmickl, R.

10.1101/2023.01.11.523565 — evolutionary biology — Posted on 2024-02-09

3258 Deciphering deep-sea chemosynthetic symbiosis by single-nucleus RNA-sequencing

Wang, H.; He, K.; Zhang, H.; Zhang, Q.; Cao, L.; Li, J.; Zhong, Z.; Chen, H.; Zhou, L.; Lian, C.; Wang, M.; Chen, K.; Qian, P.-Y.; Li, C.

10.1101/2023.05.29.542712 — ecology — Posted on 2024-02-09

3259 A Bayesian analysis of birth pulse effects on the probability of detecting Ebola virus in fruit bats

Pleydell, D. R. J.; Ndong Bass, I.; Mba Djondzo, F. A.; Meta Djomsi, D.; Kouanfack, C.; Peeters, M.; Cappelle, J.

10.1101/2023.08.10.552777 — ecology — Posted on 2024-02-09

3260 A double ovulation protocol for Xenopus laevis produces doubled fertilisation yield and moderately transiently elevated corticosterone levels without loss of egg quality

Green, J. B. A.; Moss, C.; Vacca, B.; Arnold, J.; Hubens, C.; Lynch, D. M.; Pegge, J.; Green, M. A. R.; Hosie, C. A.; Smith, T. E.

10.1101/2024.02.08.579466 — developmental biology — Posted on 2024-02-09

3261 Loss of the mitochondrial citrate carrier, SLC25A1/CIC disrupts embryogenesis via 2-Hydroxyglutarate

Kasprzyk-Pawelec, A.; Tan, M.; Phua, Y.-L.; Rahhal, R.; McIntosh, A.; Fernandez, H.; Mosaoa, R.; Cheema, A.; Jiang, L.; Popratiloff, A.; Clarkson, C.; Pearson, G. W.; Glasgow, E.; Albanese, C.; Vockley, J.; Avantaggiati, M. L.

10.1101/2023.07.18.549409 — developmental biology — Posted on 2024-02-09

3262 Tuning apicobasal polarity and junctional recycling in the hemogenic endothelium orchestrates the morphodynamic complexity of emerging pre-hematopoietic stem cells

TORCQ, L.; MAJELLO, S.; VIVIER, C.; SCHMIDT, A. A.

10.1101/2023.09.01.555862 — developmental biology — Posted on 2024-02-09

3263 BMP9 and BMP10 coordinate liver cellular crosstalk to maintain liver health

Zhao, D.; Huang, Z.; Li, X.; Wang, H.; Hou, Q.; Wang, Y.; Yan, F.; Yang, W.; Liu, D.; Yi, S.; Han, C.; Hao, Y.; Tang, L.

10.1101/2024.02.08.579542 — cell biology — Posted on 2024-02-09

3264 Sex Differences in Neural Networks Recruited by Frontloaded Binge Alcohol Drinking

Ardinger, C. E.; Chen, Y.; Kimbrough, A.; Grahame, N. J.; Lapish, C. C.

10.1101/2024.02.08.579387 — neuroscience — Posted on 2024-02-09

3265 Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning

Affan, R. O.; Bright, I. M.; Pemberton, L.; Cruzado, N. A.; Scott, B. B.; Howard, M. W.

10.1101/2024.02.05.578819 — neuroscience — Posted on 2024-02-09

3266 Goal-directed motor actions drive acetylcholine dynamics in sensory cortex

Zou, J.; Willem de Gee, J.; Mridha, Z.; Trinh, S.; Erskine, A.; Jing, M.; Yao, J.; Walker, S.; Li, Y.; McGinley, M.; Hires, S. A.

10.1101/2021.12.21.473699 — neuroscience — Posted on 2024-02-09

3267 Tension-induced adhesion mode switching: the interplay between focal adhesions and clathrin-containing adhesion complexes

Djakbarova, U.; Madraki, Y.; Chan, E.; Wu, T.; Atreaga-Muniz, V.; Akatay, A. A.; Kural, C.

10.1101/2024.02.07.579324 — cancer biology — Posted on 2024-02-09

3268 RNA Splicing Junction Landscape Reveals Abundant Tumor-Specific Transcripts in Human Cancer

Li, Q.; li, Z.; Chen, B.; Zhao, J.; Yu, H.; Hu, J.; Lai, H.; Zhang, H.; Li, Y.; Meng, Z.; Hu, Z.; Huang, S.

10.1101/2024.02.06.579246 — cancer biology — Posted on 2024-02-09

3269 Dual Targeting of Histone Deacetylases and MYC as Potential Treatment Strategy for H3-K27M Pediatric Gliomas

Algranati, D.; Oren, R.; Dassa, B.; Fellus-Alyagor, L.; Plotnikov, A.; Barr, H.; Harmelin, A.; London, N.; Ron, G.; Furth, N.; Shema, E.

10.1101/2024.02.05.578974 — cancer biology — Posted on 2024-02-09

3270 Dominant suppressor genes of p53-induced apoptosis in Drosophila melanogaster

Lukacsovich, T.; Szlanka, T.; Balint, E.; Szabo, K.; Hajdu, I.; Molnar, E.; Viragh, E.; Lin, Y. H.; Mehi, O.; Zvara, A.; Török, I.; Hegedüs, Z.; Kiss, B.; Ramasz, B.; Magdalena, L. M.; Puskas, L.; Bernard, M. M.; Fonagy, A.; Asztalos, Z.; Zurovec, M.; Boros, I.; Kiss, I.

10.1101/2024.02.06.579196 — genetics — Posted on 2024-02-09

3271 The Pseudogene RPS27AP5 Reveals Novel Ubiquitin and Ribosomal Protein Variants Involved in Specialised Ribosomal Functions.

Meller, A.; Levesque, D.; Raisch, J.; Fafard-Couture, E.; Scott, M. S.; Roucou, X.; Boisvert, F.-M.

10.1101/2024.02.05.578897 — cell biology — Posted on 2024-02-09

3272 BEND2 is a crucial player in oogenesis and reproductive aging

Huang, Y.; Bucevic, N.; Coves, C.; Felipe-Medina, N.; Marcet-Ortega, M.; Nikou, N.; Madrid-Sandin, C.; Ferrer Miralles, N.; Iborra, A.; Pendas, A. M.; Roig, I.

10.1101/2024.02.06.579114 — cell biology — Posted on 2024-02-09

3273 PLAPT: Protein-Ligand Binding Affinity Prediction Using Pretrained Transformers

Rose, T. A.; Monti, N.; Anand, N.; Shen, T.

10.1101/2024.02.08.575577 — bioinformatics — Posted on 2024-02-09

3274 PhyloAln: a convenient reference-based tool to align sequences and high-throughput reads for phylogeny and evolution in the omic era

Huang, Y.-H.; Sun, Y.-F.; Li, H.; Li, H.-S.; Pang, H.

10.1101/2024.02.08.579425 — bioinformatics — Posted on 2024-02-09

3275 Multi-genome synteny detection using minimizer graph mappings

Coombe, L.; Kazemi, P.; Wong, J.; Birol, I.; Warren, R. L.

10.1101/2024.02.07.579356 — bioinformatics — Posted on 2024-02-09

3276 Full 16S and 23S rRNA gene-based,strain-level resolution of the microbiota of a mock bacterial microbiome using ONT nanopore sequencing

Woodruff, C. J.; Zhang, Z.; Speed, T. P.

10.1101/2024.02.07.579414 — bioinformatics — Posted on 2024-02-09

3277 In vivo validation of an in situ calibration bead as a reference for backscatter coefficient calculation

Zhao, Y.; Oelze, M.; Park, T. H.; Miller, R. J.; Czarnota, G.

10.1101/2024.02.07.579320 — bioengineering — Posted on 2024-02-09

3278 Global diversity, recurrent evolution, and recent selection on amylase structural haplotypes in humans

Bolognini, D.; Halgren, A. S.; Lou, R. N.; Raveane, A.; Rocha, J.; Guarracino, A.; Soranzo, N.; Chin, J.; Garrison, E.; Sudmant, P. H.

10.1101/2024.02.07.579378 — evolutionary biology — Posted on 2024-02-09

3279 Systematic annotation of Helitron-like elements in eukaryote genomes using HELIANO

Li, Z.; Gilbert, C.; Peng, H.; Pollet, N.

10.1101/2024.02.08.579435 — evolutionary biology — Posted on 2024-02-09

3280 Geographically widespread and novel hemotropic mycoplasmas and bartonellae in Mexican free-tailed bats and sympatric North American bat species

Becker, D.; Dyer, K.; Lock, L.; Pladas, S.; Sukhadia, A.; Demory, B.; Nunes Batista, J.; Pineda, M.; Simmons, N.; Adams, A.; Frick, W.; O'Mara, T.; Volokhov, D.

10.1101/2024.02.08.577874 — ecology — Posted on 2024-02-09

3281 Differences in milk microbiota between healthy cows and cows with recurring Klebsiella mastitis

Yang, J.; Wu, N.; Xiong, Y.; Nobrega, D.; Barkema, H.; Han, B.; Gao, J.

10.1101/2024.02.08.579469 — microbiology — Posted on 2024-02-09

3282 Cocaine sensitization in male rats requires activation of estrogen receptors

Menendez-Delmestre, R.; Agosto-Rivera, J. L.; Gonzalez-Segarra, A. J.; Segarra, A. C.

10.1101/2024.02.07.579327 — neuroscience — Posted on 2024-02-09

3283 Interplay between cortical adhesion and membrane bending regulates microparticle formation

Mahapatra, A.; Malingen, S. A.; Rangamani, P.

10.1101/2024.02.07.579325 — biophysics — Posted on 2024-02-09

3284 Laser Scanning Confocal printing, a new simple method for micro-device fabrication (LSCprint method).

Megias, D.; Alonso, J. G.; Julia, J. O.; Mata, G.; Martinez, M. P.

10.1101/2024.02.08.579477 — bioengineering — Posted on 2024-02-09

3285 Transcription factors across the Escherichia coli pangenome: a 3D perspective

Moreno-Hagelsieb, G.

10.1101/2024.02.08.579464 — genomics — Posted on 2024-02-09

3286 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Phan-Canh, T.; Mair, T.; Miccolo, C.; Drino, A.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.

10.1101/2024.02.01.577722 — genetics — Posted on 2024-02-09

3287 Exploring the distribution of phylogenetic networks generated under a birth-death-hybridization process

Justison, J.; Heath, T. A.

10.1101/2022.11.10.516033 — evolutionary biology — Posted on 2024-02-09

3288 Parental effects of pathogenic bacterial infections in Drosophila melanogaster: trans-generational immune priming without apparent costs

Basu, A. K.; Prasad, N. G.

10.1101/2024.02.07.579292 — evolutionary biology — Posted on 2024-02-09

3289 Consequences of Cancer on Zebrafish Danio rerio: Insights into Sex Determination, Sex Ratio, and Offspring Survival.

Boutry, J.; Douhard, M.; Asselin, K.; Dujon, A. M.; Meliani, J.; De Backer, O.; Nicolas, D.; Shultz, A. G.; Biro, P. A.; Beckmann, C.; Fontenille, L.; Kissa, K.; Ujvari, B.; Thomas, F.

10.1101/2024.02.08.579516 — evolutionary biology — Posted on 2024-02-09

3290 Modelling the spatiotemporal dynamics of multispecies population interactions in the context of climate change

Christou, K.; Schmucki, R.; Audusseau, H.

10.1101/2024.02.07.579316 — ecology — Posted on 2024-02-09

3291 Enhanced Branched-Chain Amino Acid Metabolism Improves Age-related Reproductive Function

Lesnik, C.; Kaletsky, R.; Ashraf, J.; Sohrabi, S.; Cota, V.; Sengupta, T.; Keyes, W.; Luo, S.; Murphy, C. T.

10.1101/2023.02.09.527915 — cell biology — Posted on 2024-02-09

3292 YraN is a helicase-associated nuclease fostering extended recombination events by natural transformation

Hardy, L.; Plantade, J.; Morales, V.; Mazzamurro, F.; Rocha, E. P. C.; Polard, P.; Charpentier, X.

10.1101/2024.02.06.579203 — microbiology — Posted on 2024-02-09

3293 Metagenomic, metabolomic, and lipidomic shifts associated with fecal microbiota transplantation for recurrent Clostridioides difficile infection

McMillan, A. S.; Zhang, G.; Dougherty, M. K.; McGill, S. K.; Gulati, A. S.; Baker, E. S.; Theriot, C. M.

10.1101/2024.02.07.579219 — microbiology — Posted on 2024-02-09

3294 Evaluating Bacterial Viability in Faecal Microbiota Transplantation: A Comparative Analysis of In Vitro Cultivation and Membrane Integrity Methods

Cibulkova, I.; Rehorova, V.; Wilhelm, M.; Soukupova, H.; Hajer, J.; Duska, F.; Dankova, H.; Cahova, M.

10.1101/2024.02.08.579472 — microbiology — Posted on 2024-02-09

3295 Mosaic sarbecovirus vaccination elicits cross-reactive responses in pre-immunized animals

Cohen, A. A.; Keeffe, J. R.; Schiepers, A.; Dross, S. E.; Greaney, A. J.; Rorick, A. V.; Gao, H.; Gnanapragasam, P. N. P.; Fan, C.; West, A. P.; Ramsingh, A. I.; Erasmus, J. H.; Pata, J. D.; Muramatsu, H.; Pardi, N.; Lin, P. J. C.; Baxter, S.; Cruz, R.; Quintanar-Audelo, M.; Robb, E.; Serrano-Amatriain, C.; Magneschi, L.; Fotheringham, I. G.; Fuller, D. H.; Victora, G. D.; Bjorkman, P. J.

10.1101/2024.02.08.576722 — immunology — Posted on 2024-02-09

3296 Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages

Winnicki, A. C.; King, C. L.; Bosch, J.; Malachin, A. N.; Carias, L. L.; Skomorovska-Prokvolit, Y.; Tham, W.-H.; Dietrich, M. H.; Popovici, J.; Roobsoong, W.; Beeson, J. G.; Sattabongkot, J.; Yeoh, L. M.; Opi, D. H.; Feufack-Donfack, L. B.; Orban, A.; Drago, C. L.; McLaine, O. S.; Redinger, K. R.; Jung, N. C.; Baldor, L.

10.1101/2024.02.07.579302 — immunology — Posted on 2024-02-09

3297 Learning within a sensory-motor circuit links action to expected outcome

Zhou, W.; Schneider, D. M.

10.1101/2024.02.08.579532 — neuroscience — Posted on 2024-02-09

3298 The vitals for steady nucleation maps of spontaneous spiking coherence in autonomous two-dimensional neuronal networks

Zendrikov, D.; Paraskevov, A.

10.1101/2024.01.05.574396 — neuroscience — Posted on 2024-02-09

3299 Mapping Serotonergic Dynamics using Drug-Modulated Molecular Connectivity

Ionescu, T. M.; Amend, M.; Hafiz, R.; Maurer, A.; Biswal, B. B.; Wehrl, H. F.; Herfert, K.

10.1101/2024.02.08.579462 — neuroscience — Posted on 2024-02-09

3300 Label free, capillary-scale blood flow mapping in vivo reveals that low intensity focused ultrasound evokes persistent dilation in cortical microvasculature

Shen, Y.; Jethe, J. V.; Hehir, J.; Amaral, M. M.; Ren, C.; Hao, S.; Zhou, C.; Fisher, J. A. N.

10.1101/2024.02.08.579513 — neuroscience — Posted on 2024-02-09

3301 Microglia-astrocyte crosstalk regulates synapse remodeling via Wnt signaling

Faust, T. E.; Lee, Y.-H.; O'Connor, C. D.; Boyle, M. A.; Gunner, G.; Badimon, A.; Ayata, P. E.; Schaefer, A.; Schafer, D. P.

10.1101/2024.02.08.579178 — neuroscience — Posted on 2024-02-09

3302 Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitability

Lacoursiere, C.; Ullmann, J. F. P.; Koh, H. Y.; Turner, L.; Baker, C. M.; Robens, B.; Shao, W.; Rotenberg, A.; McGraw, C. M.; Poduri, A.

10.1101/2024.02.07.579190 — genetics — Posted on 2024-02-08

3303 Developmental disruption of the mitochondrial fissiongene drp-1 extends the longevity of daf-2 insulin/IGF-1 receptor mutant

Traa, A.; Van Raamsdonk, J.

10.1101/2024.02.07.579360 — genetics — Posted on 2024-02-08

3304 Multimodal Hox5 activity generates motor neuron diversity

KC, R.; Lopez de Boer, R.; Lin, M.; Jeannotte, L.; Philippidou, P.

10.1101/2024.02.08.579338 — developmental biology — Posted on 2024-02-09

3305 Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

Morell, C. M.; Tilson, S. G.; Tomaz, R. A.; Shahsavari, A.; Munteanu, A.; Canu, G.; Wesley, B. T.; Perrin, M.; Geti, I.; Mukhopadhyay, S.; Mazzacuva, F.; Gissen, P.; Garcia-Bernardo, J.; Bachman, M.; Rimland, C. A.; Sampaziotis, F.; Mohorianu, I.; Vallier, L.

10.1101/2024.02.07.579290 — cell biology — Posted on 2024-02-08

3306 Genome-wide transcriptional silencing and mRNA stabilization allow the coordinated expression of the meiotic program in mice

Bellutti, L.; Peng, E. C. S.; Guerquin, M.-J.; Messiaen, S.; Llano, E.; Cluzet, V.; Dereli, I.; Rolland, A. D.; Martini, E.; Toth, A.; Pendas, A. M.; Chalmel, F.; Livera, G.

10.1101/2024.02.08.579523 — cell biology — Posted on 2024-02-08

3307 Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing

Shuken, S. R.; Yu, Q.; Gygi, S. P.

10.1101/2024.02.08.579551 — cell biology — Posted on 2024-02-08

3308 Targeted Dab2 Restoration: A Novel Approach for Enhanced Wound Healing in Diabetic Conditions

Bhattacharjee, S.; Wu, H.; Wang, B.; Cui, K.; Eisa-Beygi, S.; Wang, D.; Cowan, D. B.; Wong, S.; Shi, J.; Chen, H.

10.1101/2024.02.07.579019 — cell biology — Posted on 2024-02-09

3309 Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to GDNF secretion

Yang, L.; Lin, Z.; Mu, R.; Wu, W.; Zhi, H.; Liu, X.; Yang, H.; Liu, L.

10.1101/2024.02.07.579396 — cell biology — Posted on 2024-02-09

3310 1.4 min Plasma Proteome Profiling via Nanoparticle Protein Corona and Direct Infusion Mass Spectrometry

Jiang, Y.; Meyer, J. G.

10.1101/2024.02.06.579213 — systems biology — Posted on 2024-02-08

3311 The impact of non-neutral synonymous mutations when inferring selection on non-synonymous mutations

Martinez i Zurita, A.; Kyriazis, C.; Lohmueller, K. E.

10.1101/2024.02.07.579314 — evolutionary biology — Posted on 2024-02-08

3312 Local and global changes in cell density induce reorganisation of 3D packing in a proliferating epithelium.

Barone, V.; Tagua, A.; Andres-San Roman, J. A.; Hamdoun, A.; Garrido-Garcia, J.; Lyons, D.; Escudero, L. M.

10.1101/2024.02.08.579268 — developmental biology — Posted on 2024-02-08

3313 A systems-based approach to uterine fibroids identifies differential splicing associated with abnormal uterine bleeding

Wang, C.-Y.; Philpott, M.; O'Brien, D. P.; Ndungu, A. P.; Malzahn, J.; Maritati, M.; Mehta, N.; Gamble, V.; Martinez-Burgo, B.; Bonham, S.; Fischer, R.; Garbutt, K.; Becker, C. M.; Manek, S.; Harris, A. L.; Sacher, F.; Obendorf, M.; Schmidt, N.; Müller, J.; Zollner, T. M.; Zondervan, K. T.; Kessler, B. M.; Oppermann, U.; Cribbs, A. P.

10.1101/2024.02.06.578872 — systems biology — Posted on 2024-02-08

3314 Spatially Exploring RNA Biology in Archival Formalin-Fixed Paraffin-Embedded Tissues

Bai, Z.; Zhang, D.; Gao, Y.; Tao, B.; Bao, S.; Enninful, A.; Zhang, D.; Su, G.; Tian, X.; Zhang, N.; Xiao, Y.; Liu, Y.; Gerstein, M.; Li, M.; Xing, Y.; Lu, J.; Xu, M. L.; Fan, R.

10.1101/2024.02.06.579143 — systems biology — Posted on 2024-02-08

3315 Systematic benchmarking of deep-learning methods for tertiary RNA structure prediction

Bahai, A.; Kwoh, C. K.; Mu, Y.; Li, Y.

10.1101/2024.02.08.579037 — bioinformatics — Posted on 2024-02-08

3316 CausalXtract: a flexible pipeline to extract causal effects from live-cell time-lapse imaging data

Simon, F.; Comes, M. C.; Tocci, T.; Dupuis, L.; Cabeli, V.; Lagrange, N.; Mencattini, A.; Parrini, M. C.; Martinelli, E.; Isambert, H.

10.1101/2024.02.06.579177 — systems biology — Posted on 2024-02-08

3317 Transferable deep generative modeling of intrinsically disordered protein conformations

Janson, G.; Feig, M.

10.1101/2024.02.08.579522 — bioinformatics — Posted on 2024-02-08

3318 Microbial Electrosynthesis from CO2 reaches Productivity of 1 Syngas and Chain Elongation Fermentations

Cabau-Peinado, O.; Winkelhorst, M.; Stroek, R.; de Kat Angelino, R.; Straathof, A.; Masania, K.; Daran, J.-M. G.; Jourdin, L.

10.1101/2024.02.08.579422 — bioengineering — Posted on 2024-02-08

3319 Circadian period is compensated for repressor protein turnover rates in single cells

Gabriel, C. H.; del Olmo, M. H.; Widini, A. R.; Roshanbin, R.; Woyde, J.; Hamza, E.; Gutu, N.-N.; Zehtabian, A.; Ewers, H.; Granada, A. E.; Herzel, H.; Kramer, A.

10.1101/2024.02.06.579141 — cell biology — Posted on 2024-02-08

3320 Recognition of Chlamydia trachomatis by Toll-Like Receptor 9 is altered during persistence.

Liechti, G. W.; Diallo, A.; Overman, G.; Sah, P.

10.1101/2024.02.06.579186 — microbiology — Posted on 2024-02-08

3321 Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model

Muhi, S.; Buultjens, A. H.; Porter, J. L.; Marshall, J. L.; Doerflinger, M.; Pidot, S. J.; O'Brien, D.; Johnson, P. D. R.; Lavender, C.; Globan, M.; McCarthy, J.; Osowicki, J.; Stinear, T. P.

10.1101/2024.02.08.579445 — microbiology — Posted on 2024-02-08

3322 Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex

Williams, B. G.; King, L. D. W.; Pulido, D.; Quinker, D.; Lias, A. M.; Silk, S. E.; Ragotte, R. J.; Davies, H.; Barrett, J. R.; McHugh, K.; Rigby, C. A.; Alanine, D. G. W.; Barfod, L.; Shea, M. W.; Cowley, L. A.; Dabbs, R. A.; Pattinson, D. J.; Douglas, A. D.; Lyth, O. R.; Illingworth, J. K.; Jin, J.; Carnot, C.; Kotraiah, V.; Christen, J. M.; Noe, A. R.; MacGill, R. S.; King, C. R.; Birkett, A. J.; Soisson, L. A.; Skinner, K.; Miura, K.; Long, C. A.; Higgins, M. K.; Draper, S. J.

10.1101/2024.02.08.579322 — immunology — Posted on 2024-02-08

3323 Reliable ligand discrimination in stochastic multistep kinetic proofreading: First passage time vs. product counting strategies

Li, X.; Chou, T.

10.1101/2024.02.06.579249 — systems biology — Posted on 2024-02-08

3324 A direct readout mechanism regulates the sequence selectivity of human de novo DNA methyltransferases

Barlas, A. B.; Karaca, E.

10.1101/2024.02.07.579311 — biophysics — Posted on 2024-02-08

3325 Transport mechanism of DgoT, a bacterial homolog of SLC17 organic anion transporters

Dmitrieva, N.; Gholami, S.; Alleva, C.; Carloni, P.; Alfonso-Prieto, M.; Fahlke, C.

10.1101/2024.02.07.579339 — biophysics — Posted on 2024-02-08

3326 Time-varying mediation analysis for incomplete data with application to DNA methylation study for PTSD

Wei, K.; Xue, F.; Xu, Q.; Yuan, Y.; Zhang, Y.; Qin, G.; Wani, A. H.; Aiello, A. E.; Wildman, D. E.; Uddin, M.; Qu, A.

10.1101/2024.02.06.579228 — bioinformatics — Posted on 2024-02-08

3327 GenomeFace: a deep learning-based metagenome binner trained on 43,000 microbial genomes

Lettich, R.; Egan, R.; Riley, R.; Wang, Z.; Tritt, A.; Oliker, L.; Yelick, K.; Buluc, A.

10.1101/2024.02.07.579326 — bioinformatics — Posted on 2024-02-08

3328 Invariant sets for switched systems to tackle bacterial resistance

Anderson, A.; Kinahan, M. W.; Gonzalez, A. H.; Udekwu, K.; Hernandez-Vargas, E. A.

10.1101/2024.02.06.579227 — bioinformatics — Posted on 2024-02-08

3329 Cross-species prediction of transcription factor binding by adversarial training of a novel nucleotide-level deep neural network

Zhang, Q.

10.1101/2024.02.06.579242 — bioinformatics — Posted on 2024-02-08

3330 AlphaCRV: A Pipeline for Identifying Accurate Binder Topologies in Mass-Modeling with AlphaFold

Guzman-Vega, F. J.; Arold, S. T.

10.1101/2024.02.07.578780 — bioinformatics — Posted on 2024-02-08

3331 Discovering and overcoming the bias in neoantigen identification by unified machine learning models

Zhang, Z.; Wu, W.; Wei, L.; Wang, X.

10.1101/2024.02.07.579420 — bioinformatics — Posted on 2024-02-08

3332 Measurement of adhesion and traction of cells at high yield (MATCHY) reveals an energetic ratchet driving nephron condensation

Liu, J.; Prahl, L. S.; Huang, A.; Hughes, A. J.

10.1101/2024.02.07.579368 — bioengineering — Posted on 2024-02-08

3333 Reducing Cathodic Drift during Isoelectric Focusing using Microscale Immobilized pH Gradient Gels

Lomeli, G.; Herr, A. E.

10.1101/2024.02.06.579215 — bioengineering — Posted on 2024-02-08

3334 Electrospun Poly(ε-caprolactone) Membranes Modified with Heparin and Essential Fatty Acids for Biomedical Applications

Farias, T.; Ricardo, J.; Cunha, J.; Bracelay, Y. R.; Dip, A.; Bastos, I.; Segala, K.; Junior, J. S.; Talu, s.; Paula, M.; Brito, W.

10.1101/2024.02.08.579539 — bioengineering — Posted on 2024-02-08

3335 Peptide-based capture-and-release purification of extracellular vesicles and statistical algorithm enabled quality assessment

Greenberg, Z. F.; Ali, S.; Schmittgen, T. D.; Han, S.; Hughes, S. J.; Graim, K. S.; He, M.

10.1101/2024.02.06.578050 — bioengineering — Posted on 2024-02-08

3336 Degradation of PET Plastics by Wastewater Bacteria Engineered via Conjugation

Yip, A.; McArthur, O. D.; Ho, K. C.; Aucoin, M. G.; Ingalls, B. P.

10.1101/2024.02.07.579132 — bioengineering — Posted on 2024-02-08

3337 STREAMLINED PROTEOME-WIDE IDENTIFICATION OF DRUG TARGETS INDICATES ORGAN-SPECIFIC ENGAGEMENT

Batth, T. S.; Locard-Paulet, M.; Doncheva, N. T.; Lopez-Mendez, B.; Jensen, L. J.; Olsen, J. V.

10.1101/2024.02.08.578880 — biochemistry — Posted on 2024-02-08

3338 Direct delivery of stabilized Cas-embedded base editors achieves efficient and accurate editing of clinically relevant targets

Lee, J. M.; Zeng, J.; Liu, P.; Nguyen, M. A.; Loustaunau, D. S.; Bauer, D.; Yilmaz, N. K.; Wolfe, S.; Schiffer, C. A.

10.1101/2024.02.08.579528 — biochemistry — Posted on 2024-02-08

3339 Association between mitochondrial DNA copy number and production traits in pigs

Molinero, E.; Pena, R. N.; Estany, J.; Ros-Freixedes, R.

10.1101/2024.02.07.579287 — genomics — Posted on 2024-02-08

3340 Limitations of the inference of the distribution of fitness effects of new mutations in partially selfing populations with linkage

Daigle, A.; Johri, P.

10.1101/2024.02.06.579142 — genetics — Posted on 2024-02-08

3341 DNA methylation modulates nucleosome retention in sperm and H3K4 methylation deposition in early mouse embryos.

Fanourgakis, G.; Gaspa-Toneu, L.; Komarov, P. A.; Ozonov, E. A.; Smallwood, S. A.; Peters, A. H. F. M.

10.1101/2024.02.06.579069 — genetics — Posted on 2024-02-08

3342 Experimental Snowball Earth Viscosity Drives the Evolution of Motile Multicellularity

Halling, A.; Goodson, B.; Hischmann, A.; Wing, B. A.; Simpson, C.

10.1101/2024.02.06.579218 — evolutionary biology — Posted on 2024-02-08

3343 Atypical landscape of transposable elements in the large genome of Aedes aegypti

Daron, J.; Bergman, A.; Lopez-Maestre, H.; LAMBRECHTS, L.

10.1101/2024.02.07.579293 — evolutionary biology — Posted on 2024-02-08

3344 A tension-induced morphological transition shapes the avian extra-embryonic territory

Michaut, A.; Chamolly, A.; Villedieu, A.; Corson, F.; Gros, J.

10.1101/2024.02.08.579502 — developmental biology — Posted on 2024-02-08

3345 Single-Cell Transcriptomic Profiling Unveils Critical Metabolic Alterations and Signatures in Progression of Atherosclerosis

Ma, L.; Zhao, Y.; Xiang, P.; Chen, Q.; Hassan, M.; Yu, C.

10.1101/2024.02.06.579210 — cell biology — Posted on 2024-02-08

3346 An iPSC-derived bio-inspired scaffold modelling the structure and the effects of extracellular matrix in cardiac fibrosis

Niro, F.; Fernandes, S.; Cassani, M.; Apostolico, M.; Oliver-De La Cruz, J.; Pereira-Sousa, D.; Pagliari, S.; Vinarsky, V.; Zdrahal, Z.; Potesil, D.; Pustka, V.; Pompilio, G.; Sommariva, E.; Rovina, D.; Maione, A. S.; Bersanini, L.; Becker, M.; Rasponi, M.; Forte, G.

10.1101/2024.02.07.578948 — cell biology — Posted on 2024-02-08

3347 Cytoplasmic protein-free mRNA induces stress granules by two G3BP1/2-dependent mechanisms

Ihn, S. J.; Farlam-Williams, L.; Palazzo, A. F.; Lee, H. O.

10.1101/2024.02.07.578830 — cell biology — Posted on 2024-02-08

3348 Expression interplay of calcium-binding genes and transcription factors during the osmotic phase provides insights on salt stress response mechanisms in bread wheat

Duarte-Delgado, D.; Vogt, I.; Dadshani, S.; Leon, J.; Ballvora, A.

10.1101/2024.02.07.579402 — molecular biology — Posted on 2024-02-08

3349 A meta-analysis of the gut microbiome in inflammatory bowel disease patients identifies disease-associated small molecules

Elmassry, M. M.; Sugihara, K.; Chankhamjon, P.; Camacho, F. R.; Wang, S.; Sugimoto, Y.; Chatterjee, S.; Chen, L. A.; Kamada, N.; Donia, M. S.

10.1101/2024.02.07.579278 — microbiology — Posted on 2024-02-08

3350 The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms.

Wang, Q.; Liu, J.; Luo, Y.; Kliemke, V.; Matta, G. L.; Wang, J.; Liu, Q.

10.1101/2024.02.07.579372 — microbiology — Posted on 2024-02-08

3351 Unveiling the regulatory network controlling natural transformation in lactococci

Toussaint, F.; Henry de Frahan, M.; Poncelet, F.; Ladriere, J.-M.; Horvath, P.; Fremaux, C.; Hols, P.

10.1101/2024.02.08.579460 — microbiology — Posted on 2024-02-08

3352 Site-specific sulfations regulate the physicochemical properties of papillomavirus-heparan sulfate interactions for entry

Bano, F.; Soria Martinez, L.; van Bodegraven, D.; Thorsteinsson, K.; Brown, A. M.; Fels, I.; Snyder, N. L.; Bally, M.; Schelhaas, M.

10.1101/2024.02.08.579286 — microbiology — Posted on 2024-02-08

3353 Proteomics analysis reveals novel phosphorylated residues and associated proteins of the polyomavirus DNA replication initiation complex.

Dey-Rao, R.; Shen, S.; Qu, J.; Melendy, T.

10.1101/2024.02.08.579500 — microbiology — Posted on 2024-02-08

3354 MatP delays the segregation of chromosome termini independently of cell division and tetramer formation in Vibrio cholerae

Espinosa, E.; Challita, J.; Desfontaines, J.-M.; Possoz, C.; Val, M.-E.; Mazel, D.; Marbouty, M.; Koszul, R.; Galli, E.; Barre, F. X.

10.1101/2024.02.08.578905 — microbiology — Posted on 2024-02-08

3355 Diversity of Vibrio cholerae O1 through the human gastrointestinal tract during cholera

Lypaczewski, P.; Chac, D.; Dunmire, C. N.; Tandoc, K. M.; Chowdhury, F.; Khan, A. I.; Bhuiyan, T.; Harris, J. B.; LaRocque, R. C.; Calderwood, S. B.; Ryan, E. T.; Qadri, F.; Shapiro, B. J.; Weil, A. A.

10.1101/2024.02.08.579476 — microbiology — Posted on 2024-02-08

3356 Degradation of indole-3-acetic acid by plant-associated microbes

WANG, L.; Liu, Y.; Ni, H.; Zuo, W.; Shi, H.; Liao, W.; Liu, H.; Bai, Y.; Yue, H.; Huang, A.; Friedman, J.; Si, T.; Liu, Y.; Chen, M.; Dai, L.

10.1101/2024.02.08.579438 — microbiology — Posted on 2024-02-08

3357 The signature of a T-cell response to KSHV persists across space and time in individuals with epidemic and endemic KS from Uganda

Ravishankar, S.; Towlerton, A. M. H.; Mooka, P.; Kafeero, J.; Coffey, D. G.; Aicher, L. D.; Mubiru, K. R.; Okoche, L.; Atwinirembabazi, P.; Okonye, J.; Phipps, W. T.; Warren, E. H.

10.1101/2024.02.06.579223 — immunology — Posted on 2024-02-08

3358 Model-guided metabolic engineering of curcuminoid Production in Pseudomonas putida

Martin-Pascual, M.; Moreno-Paz, S.; Van Rosmalen, R. P.; Dorigo, J.; Demaria, F.; Van Kranenburg, R.; Martins dos Santos, V.; Suarez-Diez, M. S.

10.1101/2024.02.08.579459 — synthetic biology — Posted on 2024-02-08

3359 An auxin homeostat allows plant cells to establish and control defined transmembrane auxin gradients

Geisler, M.; Dreyer, I.

10.1101/2024.02.07.579341 — plant biology — Posted on 2024-02-08

3360 Colonization by orchid mycorrhizal fungi primes induced systemic resistance against a necrotrophic pathogen

Pujasatria, G. C.; Miura, C.; Yamaguchi, K.; Shigenobu, S.; Kaminaka, H.

10.1101/2024.02.07.579401 — plant biology — Posted on 2024-02-08

3361 A novel ilarvirus protein is expressed via stop codon readthrough and suppresses RDR6-dependent RNA silencing

Lukhovitskaya, N.; Firth, A.; Brown, K.; Hua, L.; Pate, A.; Carr, J.

10.1101/2024.02.08.579442 — plant biology — Posted on 2024-02-08

3362 Arabidopsis GENOMES UNCOUPLED PROTEIN1 binds to plastid RNAs and promotes their maturation

Tang, Q.; Xu, D.; Lenzen, B.; Brachmann, A.; Yapa, M. M.; Doroodian, P.; Schmitz-Linneweber, C.; Masuda, T.; Hua, Z.; Leister, D.; Kleine, T.

10.1101/2024.02.08.579428 — plant biology — Posted on 2024-02-08

3363 Dual action of sphinganine in the plant disease resistance to bacteria.

Huby, E.; Villaume, S.; Chemotti, C.; Dorey, S.; Cordelier, S.; Crouzet, J.; Gilliard, G.; Terryn, C.; Berquand, A.; Herrfurth, C.; Feussner, I.; Jacquard, C.; Fontaine, F.; Clement, C.; Baillieul, F.; Deleu, M.; Cordelier, S.

10.1101/2024.02.07.579277 — plant biology — Posted on 2024-02-08

3364 Loop-mediated Isothermal Amplification (LAMP) assay for reliable detection of Xanthomonas axonopodis pv. vasculorum

Marabella, M.; Howard, J.; Bhandari, S.; Do, S.; Montoya-Pimolwatana, M.; Dou, Y.; Dobhal, S.; Arizala, D.; Montesinos, S.; Andreason, S. A.; Ochoa-Corona, F. M.; Bingham, J.-P.; Odani, J.; Jenkins, D.; Ma, L. M.; Fletcher, J.; Stack, J. P.; Arif, M.

10.1101/2024.02.07.579270 — plant biology — Posted on 2024-02-08

3365 Cardiac Magnetic Resonance Studies in a Large Animal Model that Simulates the Cardiac Abnormalities of Human Septic Shock

Ford, V. J.; Applefeld, W. N.; Wang, J.; Sun, J.; Solomon, S. B.; Sidenko, S.; Feng, J.; Sheffield, C.; Klein, H. G.; Yu, Z.-X.; TORABI-PARIZI, P.; Danner, R. L.; Sachdev, V.; Solomon, M. A.; Chen, M. Y.; Natanson, C.

10.1101/2024.02.05.578971 — physiology — Posted on 2024-02-08

3366 Identification of early-stage liver fibrosis by modifications in the interstitial space diffusive microenvironment using fluorescent single-walled carbon nanotubes

Lee, A.; Simon, A. A.; Boyreau, A.; Allain-Courtois, N.; Lambert, B.; PRADERE, J.-P.; SALTEL, F.; Cognet, L.

10.1101/2024.02.06.579133 — cancer biology — Posted on 2024-02-08

3367 Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer

McMahon, M.; Ghazi, P. C.; O'Toole, K. T.; Srinivas Boggaram, S.; Scherzer, M. T.; Silvis, M. R.; Zhang, Y.; Bogdan, M.; Smith, B. D.; Lozano, G.; Flynn, D. L.; snyder, e.; Kinsey, C. G.

10.1101/2024.02.06.579200 — cancer biology — Posted on 2024-02-08

3368 Single-molecule evidence of Entropic Pulling by Hsp70 chaperones

Rukes, V.; Rebeaud, M. E.; Perrin, L.; De Los Rios, P.; Cao, C.

10.1101/2024.02.06.579217 — biophysics — Posted on 2024-02-08

3369 MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities

Takeda, H.; Matsuzawa, Y.; Takeuchi, M.; Takahashi, M.; Nishida, K.; Harayama, T.; Todoroki, Y.; Shimizu, K.; Sakamoto, N.; Oka, T.; Maekawa, M.; Chung, M. H.; Kurizaki, Y.; Kiuchi, S.; Tokiyoshi, K.; Buyantogtokh, B.; Kurata, M.; Kvasnicka, A.; Takeda, U.; Uchino, H.; Hasegawa, M.; Miyamoto, J.; Tanabe, K.; Takeda, S.; Mori, T.; Kumakubo, R.; Tanaka, T.; Yoshino, T.; Arita, M.; Tsugawa, H.

10.1101/2024.02.07.579267 — bioinformatics — Posted on 2024-02-08

3370 S-nitrosylation of EZH2 at C329 and C700 interplay with PRC2 complex assembly, methyltransferase activity, and EZH2 stability to regulate endothelial functions

Sakhuja, A.; Katakia, Y. T.; Tripathi, S. M.; Bhattacharya, R.; Thakkar, N. P.; Ramakrishnan, S.; Chakraborty, S.; Thakar, S.; Sundriyal, S.; Chowdhury, S.; Majumder, S.

10.1101/2024.02.06.579117 — cell biology — Posted on 2024-02-08

3371 Roles of progranulin and FRamides in neural versus non-neural tissues on dietary restriction-related longevity and proteostasis in C. elegans

Mir, D. A.; Cox, M.; Horrocks, J.; Ma, Z.; Rogers, A. N.

10.1101/2024.02.06.579250 — molecular biology — Posted on 2024-02-08

3372 Crypt and Villus Enterochromaffin Cells are Distinct Stress Sensors in the Gut

Touhara, K. K.; Rossen, N. D.; Deng, F.; Chu, T.; Cil, O.; Li, Y.; Julius, D.

10.1101/2024.02.06.579180 — physiology — Posted on 2024-02-08

3373 Traditional uses and pharmacological activities of Tetracera alnifolia (Wild) Drake

Camara, A. K.; Balde, E. S.; Diallo, M. S. T.; Camara, M. K.; Bah, T. V.; Conde, M.; Soumah, A.; Tietjen, I.; Balde, A. M.

10.1101/2024.02.07.579282 — pharmacology and toxicology — Posted on 2024-02-08

3374 Small LEA proteins as an effective air-water interface protectant for fragile samples during cryo-EM grid plunge freezing

Abe, K. M.; Lim, C. J.

10.1101/2024.02.06.579238 — biophysics — Posted on 2024-02-08

3375 Identification of B cell subsets based on antigen receptor sequences using deep learning

Lee, H.; Shin, K.; Lee, Y.; Lee, S.; Lee, S.; Lee, E.; Kim, S. W.; Shin, H. Y.; Kim, J. H.; Chung, J.; Kwon, S.

10.1101/2024.02.06.579098 — bioinformatics — Posted on 2024-02-08

3376 A learnable transition from low temperature to high temperature proteins with neural machine translation

Komp, E.; Phillips, C.; Alanzi, H. N.; Zorman, M.; Beck, D. A. C.

10.1101/2024.02.06.579188 — bioinformatics — Posted on 2024-02-08

3377 TumFlow: An AI Model for Predicting New Anticancer Molecules

Rigoni, D.; Yaddehige, S.; Bianchi, N.; Sperduti, A.; Moro, S.; Taccioli, C.

10.1101/2024.02.06.579053 — bioinformatics — Posted on 2024-02-08

3378 BootCellNet, a resampling-based procedure, promotes unsupervised identification of cell populations via robust inference of gene regulatory networks.

Kumagai, Y.

10.1101/2024.02.06.579236 — bioinformatics — Posted on 2024-02-08

3379 Protein property prediction based on local environment by 3D equivariant convolutional neural networks

Chen, H.; Cheng, Y.; Dong, J.; Mao, J.; Wang, X.; Gao, Y.; Li, Y.; Wang, C.; Wu, Q.

10.1101/2024.02.07.579261 — bioinformatics — Posted on 2024-02-08

3380 Optimizing genomics pipeline execution with integer linear programming

Melnichenko, O.; Malladi, V.

10.1101/2024.02.06.579197 — bioinformatics — Posted on 2024-02-08

3381 Longitudinal Fragility phenotyping predicts lifespan and age-associated morbidity in C57BL/6 and Diversity Outbred mice

Luciano, A.; Robinson, L.; Garland, G.; Lyons, B.; Korstanje, R.; Di Francesco, A.; Churchill, G. A.

10.1101/2024.02.06.579096 — bioinformatics — Posted on 2024-02-08

3382 Dimensionality reduction distills complex evolutionary relationships in seasonal influenza and SARS-CoV-2

Nanduri, S.; Black, A.; Bedford, T.; Huddleston, J.

10.1101/2024.02.07.579374 — bioinformatics — Posted on 2024-02-08

3383 Exploring muscle recruitment by Bayesian methods during motion

Amankwah, M.; Bersani, A.; Calvetti, D.; Davico, G.; Somersalo, E.; Viceconti, M.

10.1101/2024.02.06.579136 — bioengineering — Posted on 2024-02-08

3384 Homologous recombination deficiency and tumor suppressor heterozygosity mediate resistance to front-line therapy in breast cancer

Safonov, A.; Marra, A.; Bandlamudi, C.; O'Leary, B.; Wubbenhorst, B.; Moiso, E.; Lee, M.; Donoghue, M.; An, J. A.-R.; Will, M.; Pareka, F.; Ahmed, M.; Nizialek, E.; Lukashchuk, N.; Sofianopoulou, E.; Liu, Y.; Huang, X.; Schultz, N.; Berger, M.; Scaltriti, M.; Reis-Filho, J. S.; Li, B. T.; Offit, K.; Norton, L.; Solit, D. B.; Shah, S.; Maxwell, K. N.; Couch, F.; Nathanson, K. L.; Robson, M. E.; Turner, N. C.; Chandarlapaty, S.; Razavi, P.

10.1101/2024.02.05.578934 — genomics — Posted on 2024-02-08

3385 Whole Genome Sequencing of DENV-2 isolated from Aedes aegypti mosquitoes in Esmeraldas, Ecuador. Genomic epidemiology of genotype III Southern Asian-American in the country.

Carrazco-Montalvo, A.; Gutierrez-Pallo, D.; Arevalo, V.; Ponce, P.; Rodriguez-Polit, C.; Alarcon, D.; Echeverria-Garces, G.; Coloma, J.; Nipaz, V.; Cevallos, V.

10.1101/2024.02.06.579255 — genomics — Posted on 2024-02-08

3386 Bigtools: a high-performance BigWig and BigBed library in Rust

Huey, J. D.; Abdennur, N. A.

10.1101/2024.02.06.579187 — genomics — Posted on 2024-02-08

3387 Screening and assessment of functional variants by regulatory features from epigenomic data in livestock species

Ma, R.; Kuang, R.; Zhang, J.; Xu, Y.; Han, Z.; Hu, M.; Wang, D.; Luan, Y.; Fu, Y.; Zhang, Y.; Li, X.; Zhu, M.; Xiang, T.; Zhao, S.; Zhao, Y.

10.1101/2024.02.06.578787 — genomics — Posted on 2024-02-08

3388 Prelude to Malignancy: A Gene Expression Signature in Normal Mammary Gland from Breast Cancer Patients Suggests Pre-tumorous Alterations and Is Associated with Adverse Outcomes

Andreou, M.; Jakalski, M.; Duzowska, K.; Filipowicz, N.; Kostecka, A.; Davies, H.; Horbacz, M.; Lawrynowicz, U.; Chojnowska, K.; Bruhn-Olszewska, B.; Jankau, J.; Srutek, E.; Las-Jankowska, M.; Bala, D.; Hoffman, J.; Hartman, J.; Peksa, R.; Skokowski, J.; Jankowski, M.; Szylberg, L.; Zegarski, W.; Nowikiewicz, M.; Nowikiewicz, T.; Dumanski, J. P.; Mieczkowski, J.; Piotrowski, A.

10.1101/2024.02.07.579074 — genomics — Posted on 2024-02-08

3389 Transcription Factor Condensates Mediate Clustering of MET Regulon and Enhancement in Gene Expression

Lee, J.; Simpson, L.; Li, Y.; Becker, S.; Zou, F.; Zhang, X.; Bai, L.

10.1101/2024.02.06.579062 — genetics — Posted on 2024-02-08

3390 A Cautionary Note on Using STRUCTURE to Detect Hybridization in a Phylogenetic Context

Pang, X.-X.; Zhang, D.-Y.

10.1101/2024.02.06.579057 — evolutionary biology — Posted on 2024-02-08

3391 How did vertebrate visual opsins diversify? - putting the last pieces of the puzzle together

Lagman, D.; Bergqvist, C. A.; Kuraku, S.

10.1101/2024.02.06.579127 — evolutionary biology — Posted on 2024-02-08

3392 Collective dynamical regimes predict invasion success and impacts in microbial communities

Hu, J.; Barbier, M.; Bunin, G.; Gore, J.

10.1101/2024.02.05.579032 — ecology — Posted on 2024-02-08

3393 Disentangling the age-dependent causal pathways affecting multiple paternity in house sparrows

Soraker, J.; Ranke, P. S.; Wright, J.; Ringsby, T. H.; Saether, B.-E.; Jensen, H.; Araya-Ajoy, Y.

10.1101/2024.02.05.579001 — ecology — Posted on 2024-02-08

3394 Old, deciduous stands support both high biodiversity and carbon storage in German forests

Springer, K.; Manning, P.; Boesing, A. L.; Ammer, C.; Fiore-Donno, A. M.; Fischer, M.; Goldmann, K.; Le Provost, G.; Overmann, J.; Ruess, L.; Schoening, I.; Seibold, S.; Sikorski, J.; Neyret, M.

10.1101/2024.02.06.578731 — ecology — Posted on 2024-02-08

3395 Arbuscular mycorrhizal fungal diversity and association networks in African tropical rainforest trees

Olanipon, D. G.; Boeraeve, M.; Jacquemyn, H.

10.1101/2024.02.06.578868 — ecology — Posted on 2024-02-08

3396 A lack of open data standards for large infrastructure project hampers social-ecological research in the Brazilian Amazon

Hyde, J.; Swanson, C.; Bohlman, S. A.; Athayde, S.; Bruna, E. M.; Valle, D. R.

10.1101/2024.02.06.579211 — ecology — Posted on 2024-02-08

3397 Disentangling competitive and cooperative components of the interactions between microbial species

Ansari, A. F.; Sambamoorthy, G.; Alexander, T. C.; Reddy, Y. B. S.; Raut, J.; Dixit, N. M.

10.1101/2024.02.06.579244 — ecology — Posted on 2024-02-08

3398 Eyespots originated multiple times independently across the Lepidoptera

Hanotte, B. P. F.; Willink, B.; Monteiro, A.

10.1101/2024.02.07.579046 — developmental biology — Posted on 2024-02-08

3399 Progressive cell fate specification in morphallactic regeneration

Nuninger, C.; Papasaikas, P.; Ferralli, J.; Smallwood, S.; Tsiairis, C. D.

10.1101/2024.02.08.579449 — developmental biology — Posted on 2024-02-08

3400 Optogenetic control of pheromone gradients reveals functional limits of mating behavior in budding yeast

Banderas, A.; Hofmann, M.; Cordier, C.; Le Bec, M.; Elizondo, C.; Chiron, L.; Pouzet, S.; Scolari, V.; Hersen, P.

10.1101/2024.02.06.578657 — cell biology — Posted on 2024-02-08

3401 Expression of elastin, FBXW2, fibrillin-1, and α-smooth muscle actin in damaged blood vessels of bovine legs

Akiyama, M.

10.1101/2024.02.06.579234 — cell biology — Posted on 2024-02-08

3402 Gentle rhodamines for live-cell fluorescence microscopy

Liu, T.; Kompa, J.; Ling, J.; Lardon, N.; Zhang, Y.; Chen, J.; Reymond, L.; Chen, P.; Tran, M.; Yang, Z.; Zhang, H.; Liu, Y.; Pitsch, S.; Zou, P.; Wang, L.; Johnsson, K.; Chen, Z.

10.1101/2024.02.06.579089 — cell biology — Posted on 2024-02-08

3403 PRMT5 deficiency disturbs Nur77 methylation to inhibit endometrial stromal cell differentiation in recurrent implantation failure

Cao, Z.; Wang, X.; Liu, Y.; Tang, X.; Wu, M.; Zhen, X.; Kang, N.; Ding, L.; Sun, J.; Cai, X.; Sun, H.; Yan, G.; JIANG, R.

10.1101/2024.02.06.579055 — cell biology — Posted on 2024-02-08

3404 Trackoscope: A Low-Cost, Open, Autonomous Tracking Microscope for Long-Term Observations of Microscale Organisms

Soneji, P.; Challita, E.; Bhamla, M. S.

10.1101/2024.02.06.579130 — microbiology — Posted on 2024-02-08

3405 NLRP3, NLRP6, and NLRP12 are inflammasomes with distinct expression patterns

Miao, E.; Wei, B.; Billman, Z.; Nozaki, K.; Goodridge, H.

10.1101/2024.02.05.579000 — immunology — Posted on 2024-02-08

3406 Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

Yasumizu, Y.; Kinoshita, M.; Zhang, M. J.; Motooka, D.; Suzuki, K.; Okuzaki, D.; Nojima, S.; Funaki, S.; Shintani, Y.; Ohkura, N.; MOrii, E.; Okuno, T.; Mochizuki, H.

10.1101/2024.02.05.579042 — immunology — Posted on 2024-02-08

3407 C. elegans RIG-I-like receptor DRH-1 signals via CARDs to activate anti-viral immunity in intestinal cells

Batachari, L. E.; Dai, A. Y.; Troemel, E.

10.1101/2024.02.05.578694 — immunology — Posted on 2024-02-08

3408 Morphologic characterization and cytokine response of chicken bone-marrow derived dendritic cells to infection with high and low pathogenic avian influenza virus

Mo, J.; Segovia, K.; Chrzastek, K.; Briggs, K.; Kapczynski, D.

10.1101/2024.02.06.579192 — immunology — Posted on 2024-02-08

3409 Backpropagation-Based Recollection of Memories: Biological Plausibility and Computational Efficiency

BEN HOUIDI, Z.

10.1101/2024.02.05.578854 — neuroscience — Posted on 2024-02-08

3410 Scrutinizing science to save lives: uncovering flaws in the data linking L-type calcium channels blockers to CRAC channels and heart failure.

Bird, G. S.; Lin, Y.-P.; Tucker, C. J.; Mueller, G.; Shi, M.; Padmanabhan, S.; Parekh, A. B.

10.1101/2024.02.06.579229 — physiology — Posted on 2024-02-08

3411 A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Saini, V. M.; Oner, E.; Ward, M.; Hurley, S.; Henderson, B. D.; Lewis, F.; Finn, S. P.; O'Leary, J.; O'Toole, S.; O'Driscoll, L.; Gately, K.

10.1101/2024.02.05.578972 — cancer biology — Posted on 2024-02-08

3412 Focal Deletions of a Promoter Tether Activate the IRX3 Oncogene in T Cell Acute Lymphoblastic Leukemia

Rahman, S.; Bloye, G.; Farah, N.; Demeulemeester, J.; Costa, J. R.; O'Connor, D.; Pocock, R.; Turna, A.; Wang, L.; Lee, S.; Fielding, A. K.; Roels, J.; Jaksik, R.; Dawidowska, M.; Vlierberghe, P. V.; Hadjur, S.; Hughes, J. R.; Davies, J. O. J.; Gutierrez, A.; Kelliher, M. A.; Loo, P. V.; Dawson, M. A.; Mansour, M. R.

10.1101/2024.02.06.579027 — cancer biology — Posted on 2024-02-08

3413 Peptide-stimulation of autologous T cells reverts immune checkpoint inhibitor resistance of hypermutated colorectal cancer cells

Schwarz, S.; Zhaoran, S.; Krohn, M.; Loeffler, M.; Schlosser, A.; Linnebacher, M.

10.1101/2024.02.06.579061 — cancer biology — Posted on 2024-02-08

3414 Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma

Gobbini, E.; Hubert, M.; Doffin, A.-C.; Eberhardt, A.; Hermet, L.; Li, D.; Duplouye, P.; Barrin, S.; Berthet, J.; Benboubker, V.; Grimont, M.; Sakref, C.; Perrot, J.; Tondeur, G.; Harou, O.; Lopez, J.; Dubois, B.; Dalle, S.; Caux, C.; Caramel, J.; Valladeau-Guilemond, J.

10.1101/2024.02.06.579128 — cancer biology — Posted on 2024-02-08

3415 Inferring the location and orientation of cell divisions on time-lapse image sequences

Karnat, M.; Saadaoui, M.; Tlili, S. L.; Karpinski, R.; Rupprecht, J.-F.

10.1101/2024.02.05.578987 — biophysics — Posted on 2024-02-08

3416 Mutant fate in spatially structured populations on graphs: connecting models to experiments

Abbara, A.; Pagani, L.; Garcia-Pareja, C.; Bitbol, A.-F.

10.1101/2024.02.06.579097 — biophysics — Posted on 2024-02-08

3417 Epithelial folding through local degradation of an elastic basement membrane plate

Guerra Santillan, K. Y.; Jantzen, C.; Dahmann, C.; Fischer-Friedrich, E.

10.1101/2024.02.06.579060 — biophysics — Posted on 2024-02-08

3418 The interplay between proton diffusion across biological membranes and their biophysical properties highlights the role of defects in mixed lipid membranes

Ramanthrikkovil Variyam, A.; Rzycki, M.; Yucknovsky, A.; Stuchebrukhov, A. A.; Drabik, D.; Amdursky, N.

10.1101/2024.02.06.579258 — biophysics — Posted on 2024-02-08

3419 Decoding cell identity with multi-scale explainable deep learning

Zhu, J.; Zhang, Z.; Xiang, Y.; Xie, B.; Dong, X.; Xie, L.; Zhou, P.; Yao, R.; Wang, X.; Li, Y.; He, F.; Zhu, W.; Zhang, Z.; Chang, C.

10.1101/2024.02.05.578922 — bioinformatics — Posted on 2024-02-08

3420 Counterfactual MRI Generation with Denoising Diffusion Models for Interpretable Alzheimer's Disease Effect Detection

Dhinagar, N. J.; Thomopoulos, S. I.; Laltoo, E.; Thompson, P. M.

10.1101/2024.02.05.578983 — bioinformatics — Posted on 2024-02-08

3421 Quantifying the seed sensitivity of cancer subclonal reconstruction algorithms

Steinberg, P. L.; Liu, L. Y.; Neiman-Golden, A.; Patel, Y.; Boutros, P. C.

10.1101/2024.02.05.579021 — bioinformatics — Posted on 2024-02-08

3422 Direct Coupling Analysis and The Attention Mechanism

Caredda, F.; Pagnani, A.

10.1101/2024.02.06.579080 — bioinformatics — Posted on 2024-02-08

3423 Integrating Safety, Security, Sustainability and Social Responsibility Principles into the U.S Bioeconomy

Gronvall, G. K.; Attal-Juncqua, A.; Getz, J.; Morhard, R.

10.1101/2024.02.05.578954 — bioengineering — Posted on 2024-02-08

3424 SMORES: A Simple Microfluidic Operating Room for the Examination and Surgery of Stentor coeruleus

Zhang, K. S.; Rodriguez, R.; Tang, S. K. Y.

10.1101/2024.02.05.578956 — bioengineering — Posted on 2024-02-08

3425 Myoelectric Prosthesis Control using Recurrent Convolutional Neural Network Regression Mitigates the Limb Position Effect

Williams, H. E.; Shehata, A. W.; Cheng, K. Y.; Hebert, J. S.; Pilarski, P. M.

10.1101/2024.02.05.578477 — bioengineering — Posted on 2024-02-08

3426 Far-red and sensitive sensor for monitoring real-time H2O2 dynamics with subcellular resolution and inmulti-parametric imaging applications.

Lee, J. D.; Nguyen, A.; Jin, Z. R.; Moghadasi, A.; Gibbs, C. E.; Wait, S. J.; Evitts, K. M.; Asencio, A.; Bremner, S. B.; Zuniga, S.; Chavan, V.; Williams, A.; Smith, N.; Regnier, M.; Young, J. E.; Mack, D. L.; Nance, E.; Boyle, P. M.; Berndt, A.

10.1101/2024.02.06.579232 — bioengineering — Posted on 2024-02-08

3427 Discovery of steroidal alkaloid metabolites and their accumulation in pigs after short-term tomato consumption

Sholola, M. J.; Goggans, M. L.; Dzakovich, M. P.; Francis, D. M.; Jacobi, S. K.; Cooperstone, J.

10.1101/2024.02.05.579005 — pharmacology and toxicology — Posted on 2024-02-08

3428 Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing

Fiflis, D. N.; Rey, N.; Lavanya, H. V.; Sewell, B.; Mitchell-Dick, A.; Milo, S.; Clements, K.; Benkert, A.; Rosales, A.; Fergione, S.; Asokan, A.

10.1101/2024.02.06.579165 — bioengineering — Posted on 2024-02-08

3429 Granulosa cell-layer stiffening prevents the granulosa cells from escaping the post-ovulatory follicle

Wang, X.; Liao, J.; Shi, H.; Zhao, Y.; Ke, W.; Wu, H.; Liu, G.; Li, X.; He, C.

10.1101/2024.02.06.579251 — cell biology — Posted on 2024-02-08

3430 Morroniside promotes skin wound re-epithelialization by facilitating epidermal stem cell proliferation through GLP-1R-mediated upregulation of β-catenin expression

Yu, C.; Yu, S.; Liu, Z.; Xu, L.; Zhang, Z.; Wan, J.; Ji, P.; Zhang, P.; Fu, Y.; Le, Y.; Ruixing, H.

10.1101/2024.02.06.579106 — pharmacology and toxicology — Posted on 2024-02-08

3431 Insulin resistance alters the coupling between cerebral blood flow and glucose metabolism in younger and older adults: Implications for neurovascular coupling

Deery, H.; Liang, E.; Di Paolo, R.; Voigt, K.; Murray, G.; Siddiqui, N.; Egan, G. F.; Moran, C.; Jamadar, S. D.

10.1101/2024.02.07.579389 — neuroscience — Posted on 2024-02-08

3432 Neural basis of self-control

Lee, K. E.; Elsey, J.; Hwang, J.; Emeric, E.; Stuphorn, V.

10.1101/2024.02.07.578652 — neuroscience — Posted on 2024-02-08

3433 Experience and behavior modulate piriform cortex odor representation in freely moving mice

Chapman, I. F.; Raymond, M. A.; Fletcher, M. L.

10.1101/2024.02.08.579489 — neuroscience — Posted on 2024-02-08

3434 Song preferences in female Java Sparrows: Familiarity or Complexity?

Lewis, R. N.; Makioka, H.; Gilman, R. T.; Soma, M.

10.1101/2024.02.08.579444 — animal behavior and cognition — Posted on 2024-02-08

3435 Evaluation of melanocyte stem cell population in vitiliginous skin pre- and post-narrow-band UVB phototherapy

Dutta, A.; Saha, D.; Poojary, M.; TS, N.; Jamora, C.

10.1101/2024.02.06.579209 — cell biology — Posted on 2024-02-08

3436 Spike Neural Network of Motor Cortex Model for Arm Reaching Controlling

Jiang, H.; Bu, X.; Sui, X.; Tang, H.; Pan, X.; Chen, Y.

10.1101/2024.02.07.579412 — neuroscience — Posted on 2024-02-08

3437 Generation of surrogate brain maps preserving spatial autocorrelation through random rotation of geometric eigenmodes

Koussis, N. C.; Pang, J. C.; Jeganathan, J.; Paton, B.; Fornito, A.; Robinson, P. A.; Misic, B.; Breakspear, M.

10.1101/2024.02.07.579070 — neuroscience — Posted on 2024-02-08

3438 Bayesian Modelling Approaches for Breath-Hold Induced Cerebrovascular Reactivity

Hayes, G.; Bulte, D. P.; Moia, S.; Craig, M.; Chappell, M.; Urunuela, E.; Sparks, S.; Caballero Gaudes, C.; Pinto, J.

10.1101/2024.02.06.579134 — neuroscience — Posted on 2024-02-08

3439 Statistical modelling of seafood fraud in the Canadian supply chain

Phillips, J. D.; De Vuono-Fraser, F. A.

10.1101/2024.02.05.578947 — genetics — Posted on 2024-02-08

3440 The genetic landscape, gene flow and adaptation in Ladakh highlanders of trans-Himalayas

Kumar, L.; Rajpal, R.; Ahlawat, B.; Pasupuleti, N.; Konar, S.; Dwivedi, A.; Kumar, S.; Spalzin, S.; Rabyang, S.; Thangaraj, K.; Rai, N.

10.1101/2024.02.05.579041 — genetics — Posted on 2024-02-08

3441 Rules of departure: Antiphony and personalized vocal spaces in wild male elephant group coordination

Rantsiou, E.; Pignatelli, A.; Mahadevan, L.

10.1101/2024.02.07.579388 — animal behavior and cognition — Posted on 2024-02-08

3442 Unravelling the microplastic menace: different polymers work in synergy to increase bee vulnerability

Ferrante, F.; Pasquini, E.; Cappa, F.; Bellocchio, L.; Baracchi, D.

10.1101/2024.02.08.579429 — animal behavior and cognition — Posted on 2024-02-08

3443 Distinct ancient structural polymorphisms control heterodichogamy in walnuts and hickories

Groh, J. S.; Vik, D. C.; Stevens, K. A.; Brown, P. J.; Langley, C. H.; Coop, G.

10.1101/2023.12.23.573205 — evolutionary biology — Posted on 2024-02-08

3444 Deep computer vision reveals the mediation of thermal-melanism and body size by precipitation and sex in a threatened alpine butterfly, Parnassius smintheus

Shirey, V.; Goswami, R.; Latronica, G. P.; Goudarzi, A.; Neupane, N.; Breed, G. A.; Ries, L.

10.1101/2024.02.05.578938 — ecology — Posted on 2024-02-08

3445 Compressive stress drives morphogenetic apoptosis

Merle, T.; Cazales, M.; Bouzignac, R.; Ronsin, B.; Rouviere, C.; Suzanne, M.

10.1101/2024.02.08.579454 — developmental biology — Posted on 2024-02-08

3446 Decoding morphogen patterning of human neural organoids with a multiplexed single-cell transcriptomic screen

Sanchis-Calleja, F.; Jain, A.; He, Z.; Okamoto, R.; Rusimbi, C.; Rifes, P.; Rathore, G. S.; Santel, M.; Janssens, J.; Seimiya, M.; Fleck, J. S.; Kirkeby, A.; Camp, J. G.; Treutlein, B.

10.1101/2024.02.08.579413 — developmental biology — Posted on 2024-02-08

3447 Altered inflammatory state and mitochondrial function identified by transcriptomics in paediatric congenital heart patients prior to surgical repair

Bartoli-Leonard, F.; Harris, A. G.; Saunders, K.; Madden, J.; Cherrington, C.; Sheehan, K.; Baquedano, M.; Parolari, G.; Bamber, A.; Caputo, M.

10.1101/2024.02.05.577755 — immunology — Posted on 2024-02-08

3448 Multi-site Ultrashort Echo Time 3D Phosphorous MRSI repeatability using novel Rosette Trajectory (PETALUTE)

Alcicek, S.; Craig-Craven, A. R.; Shen, X.; Chiew, M.; Ozen, A.; Sawiak, S.; Pilatus, U.; emir, u.

10.1101/2024.02.07.579294 — neuroscience — Posted on 2024-02-08

3449 An Atlas of Brain-Bone Sympathetic Neural Circuits

Ryu, V.; Gumerova, A. A.; Witztum, R.; Korkmaz, F.; Kannangara, H.; Moldavski, O.; Barak, O.; Lizneva, D.; Goosens, K. A.; Stanley, S.; Kim, S.-M.; Yuen, T.; Zaidi, M.

10.1101/2024.02.07.579382 — neuroscience — Posted on 2024-02-08

3450 Synchronous ensembles of hippocampal CA1 pyramidal neurons associated with theta but not ripple oscillations during novel exploration

Lin, B.-J.; Chen, T.-W.; Chen, E.-L.; Schreiter, E. R.

10.1101/2024.02.07.579313 — neuroscience — Posted on 2024-02-08

3451 Dynamic Lateralization in Contralateral-Projecting Corticospinal Neurons During Motor Learning

Han, J.; Wang, R.; Wang, M.; Yu, Z.; Zhu, L.; Zhang, J.; Zhu, J.; Zhang, S.; Xi, W.; Wu, H.

10.1101/2024.02.08.579456 — neuroscience — Posted on 2024-02-08

3452 Unlocking the secrets of kangaroo locomotor energetics: Postural adaptations underpin increased tendon stress in hopping kangaroos

Thornton, L.; Dick, T.; Hutchinson, J. R.; Lichtwark, G. A.; McGowan, C. P.; Rubenson, J.; Wiktorowicz-Conroy, A.; Clemente, C.

10.1101/2024.02.05.578950 — zoology — Posted on 2024-02-08

3453 A mathematical framework for understanding the spontaneous emergence of complexity applicable to growing multicellular systems

Zhang, L.; Xue, G.; Zhou, X.; Huang, J.; Li, Z.

10.1101/2024.02.05.578855 — systems biology — Posted on 2024-02-08

3454 Spatial transcriptomic profiling of human retinoblastoma

Wang, L.; Hung, S.; Urrutia-Cabrera, D.; Kong, R. C. K.; Staffieri, S.; Ludlow, L. E.; Lau, X.; Wang, P.-Y.; Hewitt, A. W.; Wong, R. C. B.

10.1101/2024.02.05.578886 — systems biology — Posted on 2024-02-08

3455 A foundational atlas of autism protein interactions reveals molecular convergence

Wang, B.; Vartak, R.; Zaltsman, Y.; Naing, Z. Z. C.; Hennick, K. M.; Polacco, B. J.; Bashir, A.; Eckhardt, M.; Bouhaddou, M.; Xu, J.; Sun, N.; Lasser, M.; Zhou, Y.; Guiley, K. Z.; Chan, U.; Kaye, J. A.; Khare, P.; Drake, S.; Drury, V.; Burke, D. F.; Gonzalez, S.; Alkhairy, S.; Morris, M.; Baum, T.; Krasnoff, R.; Wang, S.; Pham, P.; Arbalaez, J.; Pratt, D.; Chag, S.; Rolland, T.; Bourgeron, T.; Finkbeiner, S.; Bandyopadhay, S.; Ideker, T.; Beltrao, P.; Willsey, H. R.; Obernier, K.; Nowakowski, T. J.; Huttenhain, R.; State, M. W.; Willsey, A. J.; Krogan, N. J.

10.1101/2023.12.03.569805 — systems biology — Posted on 2024-02-08

3456 Escherichia coli sister cells dynamically organize developmental rosettes

Puri, D.; Allison, K. R.

10.1101/2023.09.18.557913 — systems biology — Posted on 2024-02-08

3457 Thermogenetics for cardiac pacing

Balatskiy, A. V.; Nesterenko, A. M.; Lanin, A. A.; Ovechkina, V. S.; Sabinin, S. S.; Fetisova, E. S.; Moshchenko, A. A.; Jappy, D.; Sokolov, R. A.; Biglova, D. Z.; Solius, G. M.; Solius, E. M.; Korolev, S. V.; Podgorny, O. V.; Kelmanson, I. V.; Rozov, A. V.; Fedotov, A. B.; Bruegmann, T.; Zheltikov, A. M.; Mozhaev, A. A.; Belousov, V. V.

10.1101/2024.01.02.573885 — synthetic biology — Posted on 2024-02-08

3458 Photoprotective mechanisms in Elysia species hosting Acetabularia chloroplasts shed light on host-donor compatibility in photosynthetic sea slugs

Morelli, L.; Havurinne, V.; Madeira, D.; Martins, P.; Cartaxana, P.; Cruz, S.

10.1101/2024.02.02.578635 — plant biology — Posted on 2024-02-08

3459 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens

Nuqui, X.; Casalino, L.; Zhou, L.; Shehata, M.; Wang, A.; Tse, A. L.; Ojha, A.; Kearns, F. L.; Rosenfeld, M. A.; Miller, E. H.; Acreman, C. M.; Ahn, S.-H.; Chandran, K.; McLellan, J. S.; Amaro, R. E.

10.1101/2023.10.24.563841 — biophysics — Posted on 2024-02-08

3460 The limits of predicting maladaptation to future environments with genomic data

Lind, B. M.; Lotterhos, K. E.

10.1101/2024.01.30.577973 — genomics — Posted on 2024-02-08

3461 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2024-02-08

3462 Automated assessments can support regional Red Lists but need to be applied with caution: A case study from central Germany

Zizka, A.; Starke-Ottich, I.; Eichenberg, D.; Boensel, D.; Zizka, G.

10.1101/2023.10.31.564918 — ecology — Posted on 2024-02-08

3463 Climate change, age acceleration, and the erosion of fitness in polar bears

Newediuk, L.; Richardson, E. S.; Biddlecombe, B. A.; Kassim, H.; Kathan, L.; Lunn, N.; Rivkin, L. R.; Salama, O. E.; Schmidt, C.; Jones, M. J.; Garroway, C. J.

10.1101/2024.01.05.574416 — ecology — Posted on 2024-02-08

3464 REL2 overexpression in the Anopheles gambiae midgut causes major transcriptional changes but fails to induce an immune response

Hoermann, A.; Capriotti, P.; Del Corsano, G.; Inghilterra, M. G.; Habtewold, T.; Cai, J. A.; Saini, G. S.; Nguyen, H.; Windbichler, N.; Christophides, G. K.

10.1101/2024.02.05.578852 — immunology — Posted on 2024-02-08

3465 Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions

Liang, Y.; Wang, H.; Sun, K.; Sun, J.; Soong, L.

10.1101/2024.02.05.578851 — immunology — Posted on 2024-02-08

3466 Differential genetic expression within reward-specific ensembles in mice

Litif, C. G.; Flom, L. T.; Sandum, K. L.; Hodgins, S. L.; Vaccaro, L.; Stitzel, J. A.; Blouin, N. A.; Mannino, M. C.; Gigley, J. P.; Schoborg, T.; Bobadilla, A.-C.

10.1101/2023.11.02.565378 — neuroscience — Posted on 2024-02-08

3467 Homeostatic regulation of REM sleep by the preoptic area of the hypothalamus

Maurer, J. J.; Lin, A.; Jin, X.; Hong, J.; Sathi, N.; Cardis, R.; Osorio-Forero, A.; Lüthi, A.; Weber, F.; Chung, S.

10.1101/2023.08.22.554341 — neuroscience — Posted on 2024-02-08

3468 Neurotensin-Neurotensin Receptor 2 signaling in adipocytes regulates food intake through ceramide metabolism

Fu, W.; Yang, Y.; Zhang, Z.; So, J.; Roh, H.-C.; Liu, T.; Xu, M.; Zheng, Y.; Huang, H.; Li, J.

10.1101/2024.02.07.579397 — physiology — Posted on 2024-02-08

3469 The molecular basis of the anticancer effect of statins

Buccioli, G.; Testa, C.; Jacchetti, E.; Pinoli, P.; Carelli, S.; Ceri, S.; Raimondi, M. T.

10.1101/2024.02.05.578869 — cancer biology — Posted on 2024-02-08

3470 Hydrodynamic Radii of Intrinsically Disordered Proteins: Fast Prediction by Minimum Dissipation Approximation and Experimental Validation

Waszkiewicz, R.; Michas, A.; Bialobrzewski, M. K.; Klepka, B. P.; Cieplak-Rotowska, M. K.; Staszalek, Z.; Cichocki, B.; Lisicki, M.; Szymczak, P.; Niedzwiecka, A.

10.1101/2024.02.05.578612 — biophysics — Posted on 2024-02-08

3471 Scaling laws of molecular residence time

Qin, S.; Yang, Z.; Huang, K.

10.1101/2024.02.05.578884 — biophysics — Posted on 2024-02-08

3472 Deciphering SH-SY5Y neuroblastoma cell proliferation: A detailed investigation of seeding concentrations, cultivation surfaces, and long-term maintenance in a sealed chamber

Kalwarczyk, E.; Lukasiak, A.; Woznica, D.; Switlik, W.; Anchimowicz, J.; Zielonka, P.; Jakiela, S.

10.1101/2024.02.05.578902 — biophysics — Posted on 2024-02-08

3473 Deleteome-Tools: Utilizing a compendium of yeast deletion strain transcriptomes to identify co-functional genes

Neal, M. L.; Choudhry, S. K.; Aitchison, J. D.

10.1101/2024.02.05.578946 — bioinformatics — Posted on 2024-02-08

3474 Fast and accurate modeling and design of antibody-antigen complex using tFold

Wu, F.; Zhao, Y.; Wu, J.; Jiang, B.; He, B.; Huang, L.; Qin, C.; Yang, F.; Huang, N.; Xiao, Y.; Wang, R.; Jia, H.; Rong, Y.; Liu, Y.; Lai, H.; Xu, T.; Liu, W.; Zhao, P.; Yao, J.

10.1101/2024.02.05.578892 — bioinformatics — Posted on 2024-02-08

3475 Genome-scale annotation of protein binding sites via language model and geometric deep learning

Yuan, Q.; Tian, C.; Yang, Y.

10.1101/2023.11.02.565344 — bioinformatics — Posted on 2024-02-08

3476 Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

Osorio, D.; Shahrouzi, P.; Tekpli, X.; Kristensen, V. N.; Kuijjer, M. L.

10.1101/2022.03.31.486602 — bioinformatics — Posted on 2024-02-08

3477 Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping

Li, Z.; Katz, S.; Martins dos Santos, V. A. P.; Fardo, D.; Claes, P.; Saccenti, E.; Van Steen, K.; Roshchupkin, G. V.

10.1101/2024.02.05.578873 — genomics — Posted on 2024-02-08

3478 Serine mistranslation induces the integrated stress response without accumulation of uncharged tRNAs

Zhang, H.; Ling, J.

10.1101/2024.02.04.578812 — genetics — Posted on 2024-02-08

3479 Biotic interactions promote local adaptation to soil in plants

Dorey, T.; Frachon, L.; Rieseberg, L. H.; Kreiner, J.; Schiestl, F.

10.1101/2024.02.05.578857 — evolutionary biology — Posted on 2024-02-08

3480 Comparison of six methods for stabilizing metapopulation dynamics and for their robustness against census noise

Singh, A.; Tung, S.

10.1101/2024.02.04.578847 — ecology — Posted on 2024-02-08

3481 The glucocorticoid receptor elicited proliferative response in human erythropoiesis is BCL11A-dependent

Mazzarini, M.; Cherone, J.; Nguyen, T.; Martelli, F.; Varricchio, L.; Funnell, A. P. W.; Papayannopoulou, T.; Migliaccio, A. R.

10.1101/2024.02.05.577972 — cell biology — Posted on 2024-02-08

3482 SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging

Tran, K. A.; Gilbert, M.; Vazquez, B. N.; Ianni, A.; Garcia, B.; Vaquero, A.; Berger, S.

10.1101/2024.02.05.578810 — cell biology — Posted on 2024-02-08

3483 Impact of Butyrate on Small and Large Airways: Effects on Cell Viability, Inflammatory Changes and Permeability

Yildiz, A. B.; Aksoy, G. T.; Konyalilar, N.; Kayalar, O.; Korkunc, S. K.; Bayram, H.

10.1101/2024.02.05.578991 — cell biology — Posted on 2024-02-08

3484 Cells limit mutagenesis by processing DNA lesions behind the replication fork

Maslowska, K. H.; Wong, R. P.; Ulrich, H. D.; Pages, V.

10.1101/2023.09.04.556208 — molecular biology — Posted on 2024-02-08

3485 Mapping the molecular motions of 5-HT3 serotonin-gated channel by Voltage-Clamp Fluorometry

Peverini, L.; Shi, S.; Medjebeur, K.; Corringer, P.-J.

10.1101/2023.09.28.559960 — molecular biology — Posted on 2024-02-08

3486 Particle size distribution shift and diurnal concentration changes of environmental DNA caused by fish spawning behaviour

Tsuji, S.; Shibata, N.

10.1101/2023.06.19.545639 — molecular biology — Posted on 2024-02-08

3487 Foxp3 depends on Ikaros for control of regulatory T cell gene expression and function

Thomas, R. M.; Pahl, M. C.; Wang, L.; Grant, S. F.; Hancock, W. W.; WELLS, A. D.

10.1101/2023.05.23.541951 — immunology — Posted on 2024-02-08

3488 Corticostriatal responses to social reward are linked to reward sensitivity and subclinical substance use

Wyngaarden, J. B.; Johnston, C. R.; Sazhin, D.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M.; Alloy, L. B.; Smith, D. V.; Jarcho, J. M.

10.1101/2023.01.17.524305 — neuroscience — Posted on 2024-02-08

3489 Neuroticism/negative emotionality is associated with increased reactivity to uncertain threat in the bed nucleus of the stria terminalis, not the amygdala

Grogans, S. E.; Hur, J.; Barstead, M. G.; Anderson, A. S.; Islam, S.; Kim, H. C.; Kuhn, M.; Tillman, R. M.; Fox, A. S.; Smith, J. F.; DeYoung, K. A.; Shackman, A. J.

10.1101/2023.02.09.527767 — neuroscience — Posted on 2024-02-08

3490 A dynamic generative model can extract interpretable oscillatory components from multichannel neurophysiological recordings

Das, P.; He, M.; Purdon, P. L.

10.1101/2023.07.26.550594 — neuroscience — Posted on 2024-02-08

3491 Disrupted cardiac bioenergetics linked to oxidized mitochondrial creatine kinase are rescued by the mitochondrial-targeting peptide SBT-20 in the D2.mdx model of Duchenne muscular dystrophy

Perry, C. G. R.; Hughes, M. C.; Ramos, S. V.; Brahmbhatt, A.; Turnbull, P. C.; Polidovitch, N.; Garibotti, M. C.; Schlattner, U.; Hawke, T. J.; Simpson, J. A.; Backx, P. H.

10.1101/2024.02.04.578832 — physiology — Posted on 2024-02-08

3492 SREBP-dependent regulation of lipid homeostasis is required for progression and growth of pancreatic ductal adenocarcinoma

Ishida, C. T.; Myers, S. L.; Shao, W.; McGuire, M. R.; Liu, C.; Kubota, C. S.; Ewachiw, T. E.; Mukhopadhyay, D.; Ke, S.; Wang, H.; Rasheed, Z. A.; Anders, R. A.; Espenshade, P. J.

10.1101/2024.02.04.578802 — cancer biology — Posted on 2024-02-08

3493 Broad de-regulated U2AF1 splicing is prognostic and augments leukemic transformation via protein arginine methyltransferase activation

Venkatasubramanian, M.; Schwartz, L.; Ramachandra, N.; Bennett, J.; Subramanian, K. R.; Gordon-Mitchell, S.; Fromowitz, A.; Pradhan, K.; Shechter, D.; Sahu, S.; Heiser, D.; Scherle, P.; Chen, X.; Chetal, C.; Kulkarni, A.; Myers, K. C.; Weirauch, M. T.; Grimes, H. L.; Starczynowski, D. T.; Verma, A.; Salomonis, N. G.

10.1101/2024.02.04.578798 — cancer biology — Posted on 2024-02-08

3494 Extrachromosomal DNA in cutaneous squamous cell carcinoma is associated with increased nodal disease

Bencomo, T.; Thind, A. S.; Ashford, B.; Ranson, M.; Lee, C. S.

10.1101/2024.02.04.578845 — cancer biology — Posted on 2024-02-08

3495 Defining the conformational states that enable transglutaminase 2 to promote cancer cell survival versus cell death

Aplin, C.; Zielinski, K. A.; Pabit, S.; Ogunribido, D.; Katt, W. P.; Pollack, L.; Cerione, R. A.; Milano, S. K.

10.1101/2024.02.04.578794 — biophysics — Posted on 2024-02-08

3496 {Omega}-Loop mutations control the dynamics of the active site by modulating a network of hydrogen bonds in PDC-3 β-lactamase

Chen, S.; Mack, A. R.; Hujer, A. M.; Bethel, C. R.; Bonomo, R. A.; Haider, S.

10.1101/2024.02.04.578824 — biophysics — Posted on 2024-02-08

3497 Elastohydrodynamic mechanisms govern beat pattern transitions in eukaryotic flagella

Veeraragavan, S.; Parast, F. Y.; Nosrati, R.; Ranganathan, P.

10.1101/2024.02.04.578806 — biophysics — Posted on 2024-02-08

3498 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality

Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.

10.1101/2023.02.24.529913 — biophysics — Posted on 2024-02-08

3499 Sterol-lipids enable large-scale, liquid-liquid phase separation in membranes of only 2 components

Wilson, K. J.; Nguyen, H. Q.; Gervay-Hague, J.; Keller, S. L.

10.1101/2024.02.02.578692 — biophysics — Posted on 2024-02-08

3500 DeepSLICEM: Clustering CryoEM particles using deep image and similarity graph representations

Palukuri, M. V.; Marcotte, E. M.

10.1101/2024.02.04.578778 — bioinformatics — Posted on 2024-02-08

3501 AAclust: k-optimized clustering for selecting redundancy-reduced sets of amino acid scales

Breimann, S.; Frishman, D.

10.1101/2024.02.04.578800 — bioinformatics — Posted on 2024-02-08

3502 Molecular structure discovery for untargeted metabolomics using biotransformation rules and global molecular networking

Martin, M.; Bittremieux, W.; Hassoun, S.

10.1101/2024.02.04.578795 — bioinformatics — Posted on 2024-02-08

3503 A self-adaptive and versatile tool for eliminating multiple undesirable variations from transcriptome

Zhang, M.; Yan, L.; Wang, X.; Yuan, Y.; Zou, S.; Yao, S.; Wang, X.; Xu, T.; Chen, B.; Yang, D.

10.1101/2024.02.04.578839 — bioinformatics — Posted on 2024-02-08

3504 Finding and Following: A deep learning-based pipeline for tracking platelets during thrombus formation in vivo and ex vivo

McGovern, A. S.; Larsson, P.; Tarlac, V.; Setiabakti, N.; Shabani Mashcool, L.; Hamilton, J. R.; Boknäs, N.; Nunez-Iglesias, J.

10.1101/2023.10.02.560609 — bioinformatics — Posted on 2024-02-08

3505 Arktos: a simple tool for the design of polyhedral DNA nanostructures

Balaji, H.; Kolipakala, R. S.; Samprathi, A. H.; Pradeep, P.; Nagarajan, D.

10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-08

3506 Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays

Van Vranken, J. G.; Li, J.; Mintseris, J.; Gadzuk-Shea, M.; Gygi, S. P.; Schweppe, D.

10.1101/2024.01.26.577428 — biochemistry — Posted on 2024-02-08

3507 ARBUR, a machine learning-based analysis system for relating behaviors and ultrasonic vocalizations of rats

Chen, Z.; Jia, G.; Zhou, Q.; Zhang, Y.; Quan, Z.; Chen, X.; Fukuda, T.; Huang, Q.; Shi, Q.

10.1101/2023.12.19.572288 — animal behavior and cognition — Posted on 2024-02-08

3508 Chronospaces: an R package for the statistical exploration of divergence times reveals extreme dependence on molecular clocks and gene choice

Mongiardino Koch, N.; Milla Carmona, P.

10.1101/2024.02.04.578835 — evolutionary biology — Posted on 2024-02-08

3509 Adaptive and pleiotropic effects of evolution in synonymous sugar environments.

Ahlawat, N.; Venkataraman, P.; Brajesh, R. G.; Saini, S.

10.1101/2024.01.28.577607 — evolutionary biology — Posted on 2024-02-08

3510 Perceptual biases, camouflage patterns, and the origin of sexual signals

Hejja-Brichard, Y.; Raymond, M.; Cuthill, I. C.; Mendelson, T. C.; Renoult, J. P.

10.1101/2023.09.27.559753 — evolutionary biology — Posted on 2024-02-08

3511 Quantifying the IUCN Red List: Using historical assessments to calculate future extinction risk

Bates, R.; Taylor, E.; Sun, Y.; Gumbs, R.; Böhm, M.; Gray, C.; Rosindell, J.

10.1101/2024.02.04.578808 — ecology — Posted on 2024-02-08

3512 Functional trade-offs: exploring the temporal response of field margin plant communities to climate change and agricultural practices

Poinas, I.; Meynard, C. N.; Fried, G.

10.1101/2023.03.03.530956 — ecology — Posted on 2024-02-08

3513 Identifying the molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish

Johal, S.; Elsayed, R.; Panfilio, K. A.; Nelson, A. C.

10.1101/2024.02.06.579092 — developmental biology — Posted on 2024-02-08

3514 Photoprotective melanin is maintained within keratinocytes in a storage lysosome

Neto, M. V.; Hall, M. J.; Charneca, J.; Escrevente, C.; Seabra, M. C.; Barral, D. C.

10.1101/2024.02.05.578910 — cell biology — Posted on 2024-02-08

3515 GSK3 inhibition ameliorates the abnormal contractility of Newfoundland ACM patient iPSC-cardiomyocytes

Noort, R. J.; Salman, W.; Porter, Z. G.; Sadighian, H.; Fuchs, C.; Braun, U.; Pace, D.; Belbin, T.; Hodgkinson, K.; Esseltine, J. L.

10.1101/2024.02.06.579108 — cell biology — Posted on 2024-02-08

3516 Single-cell trait diversity explains niche and fitness differences in aquatic microbial communities

Fontana, S.; Schmitz, D. A.; Daniels, M.; Danza, F.; Röösli, T.; Bruderer, H.; Walser, J.-C.; Dekaezemacker, J.; Escrig, S.; Meibom, A.; Pomati, F.; Schreiber, F.

10.1101/2024.02.07.579265 — microbiology — Posted on 2024-02-08

3517 Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated to queuosine tRNA modification

Fruchard, L.; Babosan, A.; Carvalho, A.; Lang, M.; Li, B.; Duchateau, M.; Giai Gianetto, Q.; Matondo, M.; Bonhomme, F.; Hatin, I.; Arbes, H.; Fabret, C.; Sanchez, G.; MArchand, V.; Motorine, Y.; NAMY, O.; de Crecy-Lagard, V.; Mazel, D.; Baharoglu, Z.

10.1101/2022.09.26.509455 — microbiology — Posted on 2024-02-08

3518 Niche formation and metabolic interactions result in stable diversity in a spatially structured cyanobacterial community

Duxbury, S. J. N.; Raguideau, S.; Cremin, K.; Rosko, J.; Coates, M.; Randall, K.; Chen, J.; Quince, C.; soyer, o. s.

10.1101/2022.12.13.520286 — microbiology — Posted on 2024-02-08

3519 Quantifying the daily harvest of fermentation products from the human gut microbiota

Arnoldini, M.; Sharma, R.; Moresi, C.; Chure, G.; Chabbey, J.; Slack, E.; Cremer, J.

10.1101/2024.01.05.573977 — microbiology — Posted on 2024-02-08

3520 Endosomal LRBA regulates the endo-lysosomal pathway

Szentgyoergyi, V.; Lueck, L. M.; Overwijn, D.; Zoeller, N. N.; Hondele, M.; Spang, A.; Bakhtiar, S.

10.1101/2024.02.07.579084 — immunology — Posted on 2024-02-08

3521 Calcitriol impairs the secretion of IL-4 and IL-13 in Th2 cells via modulating VDR-Gata3-Gfi1 axis

Biswas, B.; Chattopadhyay, S.; Hazra, S.; Goswami, R.

10.1101/2023.12.03.569823 — immunology — Posted on 2024-02-08

3522 copepodTCR: Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling

Kovaleva, V. A.; Pattinson, D. J.; Barton, C.; Chapin, S. R.; Minervina, A. A.; Richards, K. A.; Sant, A. J.; Thomas, P. G.; Pogorelyy, M. V.; Meyer, H. V.

10.1101/2023.11.28.569052 — immunology — Posted on 2024-02-08

3523 BATMAN: Improved T cell receptor cross-reactivity prediction benchmarked on a comprehensive mutational scan database

Banerjee, A.; Pattinson, D. J.; Wincek, C. L.; Bunk, P.; Chapin, S. R.; Navlakha, S.; Meyer, H. V.

10.1101/2024.01.22.576714 — immunology — Posted on 2024-02-08

3524 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition

Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.

10.1101/2020.11.25.398081 — neuroscience — Posted on 2024-02-08

3525 Plural molecular and cellular mechanisms of pore domain KCNQ2 encephalopathy

Abreo, T. J.; Thompson, E. C.; Madabushi, A.; Soh, H.; Varghese, N.; Vanoye, C. G.; Springer, K.; Park, K. L.; Johnson, J.; Sims, S.; Ji, Z.; Chavez, A. G.; Jankovic, M. J.; Habte, B.; Zuberi, A. R.; Lutz, C. M.; Wang, Z.; Krishnan, V.; Dudler, L.; Einsele-Scholz, S.; Noebels, J. L.; George, A. L.; Maheshwari, A.; Tzingounis, A.; Cooper, E.

10.1101/2024.01.04.574177 — neuroscience — Posted on 2024-02-08

3526 Modeling the Neurocognitive Dynamics of Language across the Lifespan

Guichet, C.; Banjac, S.; Mermillod, M.; Achard, S.; Baciu, M.

10.1101/2023.07.04.547510 — neuroscience — Posted on 2024-02-08

3527 Dopamine and DBS accelerate the neural dynamics of volitional action in Parkinson's disease

Köhler, R. M.; Binns, T. S.; Merk, T.; Zhu, G.; Yin, Z.; Zhao, B.; Chikermane, M.; Vanhoecke, J.; Busch, J. L.; Habets, J. G. V.; Faust, K.; Schneider, G.-H.; Cavallo, A.; Haufe, S.; Zhang, J.; Kühn, A. A.; Haynes, J.-D.; Neumann, W.-J.

10.1101/2023.10.30.564700 — neuroscience — Posted on 2024-02-08

3528 Can Prediction Error Explain Predictability Effects on the N1 during Picture-Word Verification?

Taylor, J. E.; Rousselet, G. A.; Sereno, S. C.

10.1101/2023.08.07.552265 — neuroscience — Posted on 2024-02-08

3529 Prior probability cues bias sensory encoding with increasing task exposure

Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.

10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-02-08

3530 Reconfigurations of cortical manifold structure during reward-based motor learning

Nick, Q.; Gale, D. J.; Areshenkoff, C.; De Brouwer, A. J.; Nashed, J. Y.; Wammes, J.; Zhu, T.; Flanagan, J. R.; Smallwood, J.; Gallivan, J.

10.1101/2023.07.05.547880 — neuroscience — Posted on 2024-02-08

3531 CNTN4 modulates neural elongation through interplay with APP

Bamford, R. A.; Zuko, A.; Sprengers, J. J.; Post, H.; Taggenbrock, R. L. R. E.; Mehr, A.; Jones, O. J. R.; Kudzinskas, A.; Gandawijaya, J.; Eve, M.; Muller, U. C.; Kas, M. J.; Burbach, J. P. H.; Oguro-Ando, A.

10.1101/2023.08.25.554833 — neuroscience — Posted on 2024-02-08

3532 Transport activity regulates mitochondrial bioenergetics and biogenesis in renal tubules

Cheng, C.-J.; Nizar, J. M.; Dai, D.-F.; Huang, C.-L.

10.1101/2024.02.04.578838 — physiology — Posted on 2024-02-08

3533 Hammerhead-type FXR agonists induce an eRNA FincoR that ameliorates nonalcoholic steatohepatitis in mice

Chen, J.; Wang, R.; Xiong, F.; Sun, H.; Kemper, B.; Li, W.; Kemper, J.

10.1101/2023.11.20.567833 — physiology — Posted on 2024-02-08

3534 GenerRNA: A generative pre-trained language model for de novo RNA design

Zhao, Y.; Oono, K.; Takizawa, H.; Kotera, M.

10.1101/2024.02.01.578496 — bioinformatics — Posted on 2024-02-08

3535 Simple, reference-independent analyses help optimize hybrid assembly of microbial community metagenomes

Smith, G. J.; van Alen, T. A.; van Kessel, M. A. H. J.; Luecker, S.

10.1101/2023.09.12.557416 — bioinformatics — Posted on 2024-02-08

3536 From biological data to oscillator models using SINDy

Prokop, B.; Gelens, L.

10.1101/2023.08.25.554817 — bioinformatics — Posted on 2024-02-08

3537 Eco-Anthropological factors explaining forest patch use by 3 species of wild Atelid monkeys co-existing with a small-scale farming community in Northeastern Costa Rica, Central America

Perea-Rodriguez, J. P.; Carbonero, H.; Vargas, R.; Chaves, C.

10.1101/2024.02.06.579063 — zoology — Posted on 2024-02-08

3538 Distinguishable topological properties of functional genome networks in HIV-1 reservoirs

Wisniewski, J.; Wiecek, K.; Ali, H.; Pyrc, K.; Kula-Pacurar, A.; Wagner, M.; CHEN, H.-C.

10.1101/2024.02.05.578936 — genomics — Posted on 2024-02-08

3539 Simultaneous estimation of genotype error and uncalled deletion rates in whole genome sequence data

Masaki, N.; Browning, S.; Browning, B.

10.1101/2024.02.06.579174 — genetics — Posted on 2024-02-08

3540 Bacterial ecology and evolution converge on seasonal and decadal scales

Rohwer, R. R.; Kirkpatrick, M.; Garcia, S. L.; Kellom, M.; McMahon, K. D.; Baker, B. J.

10.1101/2024.02.06.579087 — evolutionary biology — Posted on 2024-02-08

3541 Evaluating the likelihood for areas important for conservation to be recognized as Other Effective area-based Conservation Measures

Cook, C.; Rao, M.; Clyne, P.; Rathbone, V.; Grantham, H.

10.1101/2024.02.05.579011 — ecology — Posted on 2024-02-08

3542 Huntingtin is an RNA-binding protein and participates in NEAT1-mediated paraspeckles

Yadav, M.; Harding, R. J.; Li, T.; Xu, X.; Gall-Duncan, T.; Khan, M.; Ferrari Bardile, C.; Sequiera, G. L.; Duan, S.; Chandrasekaran, R.; Pan, A.; Bu, J.; Yamazaki, T.; Hirose, T.; Prinos, P.; Tippett, L.; Turner, C.; Curtis, M. A.; Faull, R. L. M.; Pouladi, M. A.; Pearson, C. E.; He, H. H.; Arrowsmith, C. H.

10.1101/2024.02.07.579162 — cell biology — Posted on 2024-02-08

3543 Anti-drift pose tracker (ADPT): A transformer-based network for robust animal pose estimation cross-species

Tang, G.; Han, Y.; Liu, Q.; Wei, P.

10.1101/2024.02.06.579164 — neuroscience — Posted on 2024-02-08

3544 In a Canine Model of Septic Shock, Cardiomyopathy Occurs Independent of Catecholamine Surges and Cardiac Microvascular Ischemia

Ford, V. J.; Applefeld, W. N.; Wang, J.; Sun, J.; Solomon, S. B.; Klein, H. G.; Feng, J.; Lertora, J.; TORABI-PARIZI, P.; Danner, R. L.; Solomon, M. A.; Chen, M. Y.; Natanson, C.

10.1101/2024.02.05.578927 — physiology — Posted on 2024-02-08

3545 ASPYRE-Lung: Validation of a simple, fast, robust and novel method for multi-variant genomic analysis of actionable NSCLC variants in tissue

Evans, R. T.; Gillon-Zhang, E.; Brown, J. N.; Knudsen, K. E.; King, C.; Green, A. S.; Silva, A.-L.; Mordaka, J. M.; Palmer, R. N.; Tomassini, A.; Collazos, A.; Xyrafaki, C.; Turner, I.; Ho, C. H.; Nugent, D.; Jose, J.; Andreazza, S.; von Bargen, K.; Gray, E. R.; Stolarek-Januszkiewicz, M.; Cooke, A.; Reddi, H.; Balmforth, B.; Osborne, R. J.

10.1101/2024.02.07.579135 — cancer biology — Posted on 2024-02-08

3546 Resistance genes are distinct in protein-protein interaction networks according to drug class and gene mobility

Moumi, N. A.; Brown, C.; Ahmed, S.; Vikesland, P.; Pruden, A.; Zhang, L.

10.1101/2024.02.05.578986 — bioinformatics — Posted on 2024-02-08

3547 Multitask Knowledge-primed Neural Network for Predicting Missing Metadata and Host Phenotype based on Human Microbiome

Monshizadeh, M.; Hong, Y.; Ye, Y.

10.1101/2024.02.05.578930 — bioinformatics — Posted on 2024-02-08

3548 Explaining Conformational Diversity in Protein Families through Molecular Motions

Lombard, V.; Grudinin, S.; Laine, E.

10.1101/2024.02.06.578951 — bioinformatics — Posted on 2024-02-08

3549 Feature Reuse and Scaling: Understanding Transfer Learning with Protein Language Models

Li, F.-Z.; Amini, A. P.; Yue, Y.; Yang, K. K.; Lu, A. X.

10.1101/2024.02.05.578959 — bioengineering — Posted on 2024-02-08

3550 First draft genome assembly and characterization of sponge Halisarca dujardinii reveals key components of basement membrane and broad repertoire of aggregation factors

Borisenko, I.; Predeus, A. V.; Lavrov, A.; Ereskovsky, A.

10.1101/2024.02.06.578935 — genomics — Posted on 2024-02-08

3551 What is the correct genomic structure of the complex chromosomal rearrangement at the Fm locus in Silkie chicken?

Sharma, A.; Vijay, N.

10.1101/2024.02.05.578760 — genomics — Posted on 2024-02-08

3552 Rtt107 cooperates with Rad55 or Slx4 to maintain genome stability in Saccharomyces cerevisiae

Brown, J. A. R.; Kobor, M. S.

10.1101/2024.02.05.579050 — genetics — Posted on 2024-02-08

3553 High-recombining genomic regions affect demography inference

Ishigohoka, J.; Liedvogel, M.

10.1101/2024.02.05.579015 — evolutionary biology — Posted on 2024-02-08

3554 Evolutionary analysis of genome-specific duplications in flatworm genomes

Langleib, M.; Calvelo, J.; Costabile, A.; Castillo, E.; Tort, J. F.; Hoffmann, F. G.; Protasio, A. V.; Koziol, U.; Iriarte, A.

10.1101/2024.02.05.578899 — evolutionary biology — Posted on 2024-02-08

3555 Accumulation dynamics of defective genomes during experimental evolution of two betacoronaviruses

Hillung, J.; Olmo-Uceda, M. J.; Munoz-Sanchez, J. C.; Elena, S. F.

10.1101/2024.02.06.579167 — evolutionary biology — Posted on 2024-02-08

3556 Regulatory divergences in dosage compensation cause hybrid male inviability in Caenorhabditis

Li, Y.; Gao, Y.; Ma, J.; Gao, Y.; Zhou, W.; Zhang, H.; Shao, W.; Liu, Z.; Zhao, Z.; Liu, X.

10.1101/2024.02.06.577000 — evolutionary biology — Posted on 2024-02-08

3557 Arktos: a simple tool for the design of polyhedral 1DNA nanostructures

Balaji, H.; Kolipakala, R. S.; Samprathi, A. H.; Pradeep, P.; Nagarajan, D.

10.1101/2024.02.07.576791 — bioinformatics — Posted on 2024-02-08

3558 Intrinsic structural disorder on proteins is involved in the interactome evolution

Bustos, D. M.

10.1101/2024.02.05.578866 — bioinformatics — Posted on 2024-02-08

3559 Extensive novel diversity and phenotypic associations in the dromedary camel microbiome are revealed through deep metagenomics and machine learning

Mubaraki, F. A.

10.1101/2024.02.05.578850 — bioinformatics — Posted on 2024-02-08

3560 Microtubule perturbations of neurite extension and nucleokinesis in an iPSC-derived model system

Sebastien, M.; Paquette, A. L.; Hendricks, A. G.; Brouhard, G. J.

10.1101/2024.02.06.579144 — cell biology — Posted on 2024-02-07

3561 Recent statistics shift object representations in parahippocampal cortex

Solomon, S. H.; Kay, K.; Schapiro, A. C.

10.1101/2024.02.07.579310 — neuroscience — Posted on 2024-02-07

3562 Augmented Reality and Cross-Device Interaction for Seamless Integration of Physical and Digital Scientific Papers

Miah, M. O.; Kong, J.

10.1101/2024.02.05.578116 — scientific communication and education — Posted on 2024-02-08

3563 Long-term disruption of glucose homeostasis in a rodent model of preterm birth.

Diao, S.; Guenoun, D.; Chen, S.-P.; CRUCIANI-GUGLIELMACCI, C.; Pansiot, J.; Laforge, M.; Raho, I.; Faivre, V.; Degos, V.; Gressens, P.; Nadjar, A.; Van Steenwinckel, J.; Adle-Biasette, H.; Magnan, C.; Jacquens, A.; Bokobza, C.

10.1101/2024.02.07.579307 — physiology — Posted on 2024-02-07

3564 Building and analyzing metacells in single-cell genomics data

Bilous, M.; Herault, L.; Gabriel, A. A.; Teleman, M.; Gfeller, D.

10.1101/2024.02.04.578815 — bioinformatics — Posted on 2024-02-08

3565 A real-time, high-performance brain-computer interface for finger decoding and quadcopter control

Willsey, M. S.; Shah, N. P.; Avansino, D. T.; Hahn, N. V.; Jamiolkowski, R. M.; Kamdar, F. B.; Hochberg, L. R.; Willett, F. R.; Henderson, J. M.

10.1101/2024.02.06.578107 — bioengineering — Posted on 2024-02-08

3566 BayVarC: an ultra-sensitive ctDNA variant caller using Bayesian approach

Che, D.; Yan, C.; Zha, J.; Niu, Z.; Yang, Q.; Cheng, X.; Han, M.; Du, C.; Zhang, K.; Hu, Y.; Yang, Y.-F.

10.1101/2024.02.03.578772 — bioinformatics — Posted on 2024-02-07

3567 Personalized Molecular Signatures of Insulin Resistance and Type 2 Diabetes

Larsen, J.; Stocks, B.; Henderson, J.; Andersson, D.; Backdahl, J.; Eriksson-Hogling, D.; Stidsen, J.; Sakamoto, K.; Hojlund, K.; Ryden, M.; Zierath, J. R.; Krook, A.; Deshmukh, A. S.

10.1101/2024.02.06.578994 — biochemistry — Posted on 2024-02-07

3568 One-step N-terminomics based on isolation of protein N-terminal peptides from LysargiNase digests by tip-based strong cation exchange chromatography

Morikawa, K.; Nishida, H.; Imami, K.; Ishihama, Y.

10.1101/2024.02.06.579163 — biochemistry — Posted on 2024-02-07

3569 Genetic and functional dissection of the glutamate-proline pathway reveals a shortcut for glutamate catabolism in Leishmania

Campagnaro, G. D.; Cruz, A. K.

10.1101/2024.02.06.579205 — biochemistry — Posted on 2024-02-07

3570 Influence of S100A9 on Prion Protein Amyloid Aggregation

Ziaunys, M.; Sulskis, D.; Mikalauskaite, K.; Sakalauskas, A.; Smirnovas, V.

10.1101/2024.02.06.579161 — biochemistry — Posted on 2024-02-07

3571 Beta-Glucanase superfamily identified by sequential, functional, and structural analyses

Nakajima, M.; Tanaka, N.; Motouchi, S.; Kobayashi, K.; Shimizu, H.; Abe, K.; Hosoyamada, N.; Abara, N.; Morimoto, N.; Hiramoto, N.; Nakata, R.; Takashima, A.; Hosoki, M.; Suzuki, S.; Shikano, K.; Fujimaru, T.; Imagawa, S.; Kawadai, Y.; Wang, Z.; Kitano, Y.; Nihira, T.; Nakai, H.; Taguchi, H.

10.1101/2024.02.06.578578 — biochemistry — Posted on 2024-02-07

3572 Formylation facilitates the reduction of oxidized initiator methionines

Tan, R.; Hoare, M.; Bellomio, P.; Broas, S.; Camacho, K.; Swovick, K.; Welle, K. A.; Hryhorenko, J. R.; Ghaemmaghami, S.

10.1101/2024.02.06.579201 — biochemistry — Posted on 2024-02-07

3573 Peripheral mutations underlie promiscuous transport of quaternary ammonium antiseptics by Small Multidrug Resistance transporters

Burata, O. E.; O'Donnell, E.; Hyun, J.; Lucero, R. M.; Thomas, J. E.; Gibbs, E. M.; Reacher, I.; Carney, N. A.; Stockbridge, R. B.

10.1101/2024.02.06.579181 — biochemistry — Posted on 2024-02-07

3574 Complementary human gene interaction maps from radiation hybrids and CRISPRi

Smith, D. J.

10.1101/2024.02.05.579036 — genomics — Posted on 2024-02-07

3575 Assessment of salivary microRNA by RT-qPCR: Challenges in data interpretation for clinical diagnosis

Van Der Hofstadt, M.; Cardinal, A.; Lepeltier, M.; Boulestreau, J.; Ouedraogo, A.; Kahli, M.; Molina, L.; Molina, F.; Van, T. N. N.

10.1101/2024.02.06.579150 — molecular biology — Posted on 2024-02-07

3576 Rendering the metabolic wiring powering wetland soil methane production

Oliverio, A. M.; Narrowe, A. B.; Villa, J. A.; Rinke, C.; Hoyt, D. W.; Liu, P.; McGivern, B. B.; Bechtold, E. K.; Ellenbogen, J. B.; Daly, R. A.; Smith, G. J.; Angle, J. C.; Flynn, R. M.; Freiburger, A. P.; Louie, K. B.; Stemple, B.; Northen, T.; Henry, C.; Miller, C.; Morin, T. H.; Bohrer, G.; Borton, M. A.; Wrighton, K. C.

10.1101/2024.02.06.579222 — microbiology — Posted on 2024-02-07

3577 Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection

Chang, C. R.; Vykunta, V. S.; Goodman, D. B.; Muldoon, J. J.; Nyberg, W. A.; Liu, C.; Allain, V.; Rothrock, A.; Wang, C. H.; Marson, A.; Shy, B. R.; Eyquem, J.

10.1101/2024.02.06.576175 — synthetic biology — Posted on 2024-02-07

3578 DNA representations and generalization performance of sequence-to-expression models

Shen, Y.; Kudla, G.; Oyarzun, D. A.

10.1101/2024.02.06.579067 — synthetic biology — Posted on 2024-02-07

3579 Engineering an anti-CD206-synNotch receptor: insightsinto the development of novel synthetic receptors

Semeniuk, S.; Qian, B.; Cachat, E.

10.1101/2024.02.07.579082 — synthetic biology — Posted on 2024-02-07

3580 Optogenetic Regulation of EphA1 RTK Activation and Signaling

Wurz, A. I.; Zheng, K. S.; Hughes, R. M.

10.1101/2024.02.06.579139 — synthetic biology — Posted on 2024-02-07

3581 A three-dimensional, discrete-continuum model of blood pressure in microvascular networks

Sweeney, P. W.; Walsh, C.; Walker-Samuel, S.; Shipley, R. J.

10.1101/2022.11.23.517681 — biophysics — Posted on 2024-02-07

3582 IL-1β disrupts blood-brain barrier development by inhibiting endothelial Wnt/β-catenin signaling

Fetsko, A. R.; Sebo, D. J.; Budzynski, L. B.; Scharbarth, A.; Taylor, M. R.

10.1101/2023.12.04.569943 — cell biology — Posted on 2024-02-07

3583 Prediction of Bovine coronavirus immune epitopes using selection and phylogenetic analysis

Russell, T.; Lozano, J. M.; Challinor, C.; Barry, G.

10.1101/2023.09.14.557617 — microbiology — Posted on 2024-02-07

3584 Sensory neuron population expansion enhances odour tracking without sensitising projection neurons

10.1101/2023.09.15.556782 — neuroscience — Posted on 2024-02-07

3585 Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway

Shaikh, R.; Larson, N. J.; Hanjaya-Putra, D.; Zartman, J. J.; Umulis, D. M.; Li, L.; Reeves, G. T.

10.1101/2024.02.01.578451 — systems biology — Posted on 2024-02-07

3586 Regulation of a single Inositol 1-Phosphate Synthase homeolog by HSFA6B contributes to fiber yield maintenance under drought conditions in upland cotton

Yu, L.; Nelson Dittrich, A. C.; Zhang, X.; Thirumalaikumar, V. P.; Melandri, G.; Skirycz, A.; Thorp, K. R.; Hinze, L. L.; Nelson, A. D. L.; Pauli, D.

10.1101/2022.06.10.495687 — plant biology — Posted on 2024-02-07

3587 Phenotypic, genomic, and transcriptomic heterogeneity in a pancreatic cancer cell line

Xie, G.; Zhang, L.; Usman, O. H.; Kumar, S.; Modak, C.; Patel, D.; Kavanaugh, M.; Mallory, X.; Wang, Y. J.; Irianto, J.

10.1101/2022.11.11.516211 — cancer biology — Posted on 2024-02-07

3588 Structural insights into the orthosteric inhibition of P2X receptors by non-ATP-analog antagonists

Sheng, D.; Yue, C.; Jin, F.; Wang, Y.; Ichikawa, M.; Yu, Y.; Guo, C.-R.; Hattori, M.

10.1101/2023.09.15.558037 — biophysics — Posted on 2024-02-07

3589 Deep learning-based proteomics enables accurate classification of bulk and single-cell samples

Krull, K. K.; Kuehn, A.; Hoehn, J.; Brinker, T. J.; Krijgsveld, J.

10.1101/2024.02.03.578734 — bioinformatics — Posted on 2024-02-07

3590 Kinase activity of histone chaperone APLF maintains steady state of centrosomes in mouse embryonic stem cells

Dutta, D.; Rajam, S. M.; Varghese, P. C.; Shirude, M. B.; Syed, K. M.; Devarajan, A.; Natarajan, K.

10.1101/2024.02.06.579158 — biochemistry — Posted on 2024-02-07

3591 Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1

Khamrui, S.; Dodatko, T.; Wu, R.; Leandro, J.; Sabovic, A.; Violante, S.; Cross, J. R.; Marsan, E.; Kumar, K.; DeVita, R.; Lazarus, M. B.; Houten, S.

10.1101/2024.02.07.578422 — biochemistry — Posted on 2024-02-07

3592 HDAC1/2 and HDAC3 play distinct roles in controlling adult Meibomian gland homeostasis

Zhu, X.; Xu, M.; Millar, S. E.

10.1101/2024.02.06.579230 — molecular biology — Posted on 2024-02-07

3593 CD81-guided heterologous EVs present heterogeneous interactions with breast cancer cells

Gurrieri, E.; Carradori, G.; Roccuzzo, M.; Pancher, M.; Peroni, D.; Belli, R.; Trevisan, C.; Notarangelo, M.; Huang, W.-Q.; Carreira, A. S.; Quattrone, A.; Jenster, G.; Ten Hagen, T. L.; D'Agostino, V. G.

10.1101/2024.02.06.579138 — molecular biology — Posted on 2024-02-07

3594 Localization of Human UBE3A Isoform 3 is Highly Sensitive to Amino Acid Substitutions at p.Met21 Position

van Esbroeck, A. C. M.; Verhagen, R. F. M.; Biagioni, M.; Fossati, M.; Distel, B.; Elgersma, Y.

10.1101/2024.02.05.578859 — molecular biology — Posted on 2024-02-07

3595 Mutualism provides the basis for biodiversity in eco-evolutionary community assembly

Araujo, G.; Lurgi, M.

10.1101/2024.02.02.578708 — ecology — Posted on 2024-02-07

3596 Interplay of condensation and chromatin binding underlies BRD4 targeting

Strom, A. R.; Eeftens, J. M.; Polyachenko, Y.; Weaver, C. J.; Watanabe, H.-F.; Bracha, D.; Orlovsky, N. D.; Jumper, C. C.; Jacobs, W. M.; Brangwynne, C. P.

10.1101/2024.02.07.579384 — molecular biology — Posted on 2024-02-07

3597 Catalytic-independent functions of INTAC in conferring sensitivity to BET inhibition

FAN, P.; SHANG, X.-Y.; SONG, A.; CHEN, S.; MAO, R.-Y.; CHEN, J.; WANG, Z.; ZHENG, H.; TAO, B.; XU, W.; JIANG, W.; YANG, H.; XU, C.; ZHANG, P.; Jiang, H.; CHEN, F. X.

10.1101/2024.02.07.579305 — molecular biology — Posted on 2024-02-07

3598 Small molecule inhibitors of hnRNPA2B1-RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesicles

Corsi, J.; Peroni, D.; Belli, R.; Lassandro, M.; Sidarovich, V.; Adami, V.; Grosskreutz, J.; Fabbiano, F.; Grossmann, D.; Hermann, A.; Tell, G.; Basso, M.; D'Agostino, V. G.

10.1101/2024.02.05.578546 — molecular biology — Posted on 2024-02-07

3599 A rapid, cost-effective, colorimetric LAMP assay (CLASS) for detecting invasive malaria vector, Anopheles stephensi

Rafferty, C.; Raise, G.; Scaife, J.; Abongo, B.; Omondi, S.; Milanoi, S.; Muchoki, M.; Onyango, B.; Ochomo, E.; Zohdy, S.

10.1101/2024.02.06.579110 — molecular biology — Posted on 2024-02-07

3600 Polyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans

Peters, L.; Drechsler, M.; Pees, B.; Angelidou, G.; Salzer, L.; Moors, K. A.; Paczia, N.; Schulenburg, H.; Shi, Y.-M.; Kaleta, C.; Witting, M.; Bode, H. B.; Dierking, K.

10.1101/2024.02.06.579051 — molecular biology — Posted on 2024-02-07

3601 Substrate stiffness modulates the emergence and magnitude of senescence phenotypes

Starich, B.; Yang, F.; Tanrioven, D.; Kung, H.-C.; Baek, J.; Nair, P. R.; Kamat, P.; Macaluso, N.; Eoh, J.; Han, K. S.; Gu, L.; Sun, S.; Wu, P.-H.; Wirtz, D.; Phillip, J. M.

10.1101/2024.02.06.579151 — molecular biology — Posted on 2024-02-07

3602 DOT1L stimulates MYC/Mondo transcription factor activity by promoting its degradation cycle on chromatin

Sepulveda, G. P.; Gushchanskaia, E. S.; Mora-Martin, A.; Esse, R.; Nikorich, I.; Ceballos, A.; Kwan, J.; Blum, B. C.; Dholiya, P.; Emili, A.; Perissi, V.; Cardamone, M. D.; Grishok, A.

10.1101/2024.02.06.579191 — molecular biology — Posted on 2024-02-07

3603 Mathematical modeling suggests heterogeneous replication of Mycobacterium tuberculosis in rabbits

Ganusov, V. V.; Kolloli, A.; Subbian, S. V.

10.1101/2024.02.07.579301 — microbiology — Posted on 2024-02-07

3604 PluMu - a Mu-like bacteriophage infecting Actinobacillus pleuropneumoniae

Bartsch, L. J.; Fernandez Crespo, R.; Wang, Y.; Skinner, M. A.; Rycroft, A. N.; Cooley, W.; Everest, D. J.; Li, Y.; Bosse, J. T.; Langford, P. R.

10.1101/2024.02.07.579279 — microbiology — Posted on 2024-02-07

3605 The Streptococcus pyogenes M protein is involved in phenotypic resistance to phage A25 infection in presence of human serum.

Schiavolin, L.; Steinmetz, J.; Botquin, G.; Delforge, V.; Lakhloufi, D.; Smeesters, P. R.; Botteaux, A.

10.1101/2024.02.07.579182 — microbiology — Posted on 2024-02-07

3606 Competitive advantages of secondary adsorption-triggered lysis inhibition for T-even phages

Hvid, U.; Mitarai, N.

10.1101/2024.02.07.579269 — microbiology — Posted on 2024-02-07

3607 Weather-related changes in the dehydration of respiratory droplets on surfaces bolster bacterial endurance

Rasheed, A.; Parmar, K.; Jain, S.; Chakravortty, D.; Basu, S.

10.1101/2024.02.07.579296 — microbiology — Posted on 2024-02-07

3608 Single-cell trait diversity explains niche and fitness differences in aquatic microbial communities

Fontana, S.; Schmitz, D. A.; Daniels, M.; Danza, F.; Röösli, T.; Bruderer, H.; Walser, J.-C.; Dekaezemacker, J.; Escrig, S.; Meibom, A.; Pomati, F.; Schreiber, F.

10.1101/2024.02.07.579265 — microbiology — Posted on 2024-02-07

3609 Exploring the metabolic potential of Aeromonas to utilise the carbohydrate polymer chitin

Tugui, C.; Sorokin, D.; Hijnen, W.; Wunderer, J.; Bout, K.; van Loosdrecht, M.; Pabst, M.

10.1101/2024.02.07.579344 — microbiology — Posted on 2024-02-07

3610 Convergent within-host evolution alters key virulence factors in a Klebsiella pneumoniae clone during a large hospital outbreak

Zaborskyte, G.; Hjort, K.; Lytsy, B.; Sandegren, L.

10.1101/2024.02.06.577356 — microbiology — Posted on 2024-02-07

3611 Positive serial dependence in ratings of food images for appeal and calories

Alais, D.; Carlson, T.

10.1101/2024.02.07.579264 — neuroscience — Posted on 2024-02-07

3612 Dispensable regulation of brain development and myelination by Serpina3n

Guo, F.; Zhu, M.; wang, y.; Park, J.; Gong, S.

10.1101/2024.02.06.579239 — neuroscience — Posted on 2024-02-07

3613 Adult Single-nucleus Neuronal Transcriptomes of Insulin Signaling Mutants Reveal Regulators of Behavior and Learning

St. Ange, J.; Weng, Y.; Stevenson, M.; Kaletsky, R.; Moore, R. S.; Zhou, S.; Murphy, C.

10.1101/2024.02.07.579364 — neuroscience — Posted on 2024-02-07

3614 Enhancing Plant Photosynthesis using Carbon Dots as Light Converter and Photosensitizer

Hu, H.; Cheng, W.; Wang, X.; Yang, Y.; Yu, X.; Ding, J.; Lin, Y.; Zhao, W.; Zhao, Q.; Ledesma-Amaro, R.; Chen, X.; Liu, J.; Yang, C.; Gao, X.

10.1101/2024.02.06.579025 — synthetic biology — Posted on 2024-02-07

3615 Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling

Koudelka, A.; Buchan, G. J.; Cechova, V.; O`Brien, J. P.; Liu, H.; Woodcock, S. R.; Mullett, S. J.; Zhang, C.; Freeman, B. A.; Gelhaus, S. L.

10.1101/2024.02.06.579101 — biochemistry — Posted on 2024-02-07

3616 Less activity means improved welfare? How pair housing influences pinyon jay (Gymnorhinus cyanocephalus) behavior

Wolff, L. M.; Stevens, J. R.

10.1101/2024.02.07.579343 — animal behavior and cognition — Posted on 2024-02-07

3617 Altered spawning seasons of Atlantic salmon broodstock genetically and epigenetically influence cell cycle and lipid-mediated regulations in their offspring

Saito, T.; Espe, M.; Mommens, M.; Bock, C.; Fernandes, J. M. O.; Skjaerven, K. H.

10.1101/2024.02.03.578741 — genomics — Posted on 2024-02-07

3618 Diversity, Origin and Evolution of the ESCRT Systems

Makarova, K. S.; Tobiasson, V.; Wolf, Y. I.; Lu, Z.; Liu, Y.; Zhang, S.; Krupovic, M.; Li, M.; Koonin, E. V.

10.1101/2024.02.06.579148 — evolutionary biology — Posted on 2024-02-07

3619 Multiple plastid losses within photosynthetic stramenopiles revealed by comprehensive phylogenomics

Terpis, K.; Salomaki, E.; Barcyte, D.; Panek, T.; Verbruggen, H.; Kolisko, M.; Bailey, J. C.; Elias, M.; Lane, C.

10.1101/2024.02.03.578753 — evolutionary biology — Posted on 2024-02-07

3620 Changing rounds into squares or combining stripes: Diversity and formation of checkerboard patterns in Eukaryotes

Galipot, P.; Zalko, J.

10.1101/2024.02.07.579346 — developmental biology — Posted on 2024-02-07

3621 miR-203 controls timing of developmental transitions during early preimplantation embryogenesis

Gonzalez-Martinez, J.; Ayala, E.; Sanchez-Belmonte, A.; Garcia, A.; Nogueira, E.; Melati, A.; Gimenez, D.; Losada, A.; Ortega, S.; Malumbres, M.

10.1101/2024.02.06.579214 — developmental biology — Posted on 2024-02-07

3622 Genetic Studies Highlight the Role of TET2 and INO80 in DNA Damage Response and Kidney Disease Pathogenesis

Liang, X.; Liu, H.; Hu, H.; Zhou, J.; Abedini, A.; Navarro, A. S.; Klotzer, K. A.; Susztak, K.

10.1101/2024.02.02.578718 — genetics — Posted on 2024-02-07

3623 The 4T1 breast carcinoma model possesses hybrid epithelial/mesenchymal traits linked to a highly metastatic phenotype

Herndon, M. E.; Gibson-Corley, K.; Wallrath, L. L.; Henry, M.; Stipp, C. S.

10.1101/2024.02.02.578710 — cancer biology — Posted on 2024-02-07

3624 Shift in cellular crosstalk reveals the immunosuppressive environment in cholangiocarcinoma patients.

Heij, L. R.; Hayat, S.; Reichel, K.; Maryam, S.; Rourke, C.; Tan, X.; van den Braber, M.; Verhoeff, J.; Halder, M.; Peisker, F.; Wiltberger, G.; Bednarsch, J.; Heise, D.; Campello Deierl, J.; Lang, S.; Ulmer, F.; Luedde, T.; Dahl, E.; Jonigk, D.; Nolting, J.; Sivakumar, S.; Siveke, J.; Rocha, F.; Baba, H.; Andersen, J.; Garcia Vallejo, J.; Kramann, R.; Neumann, U.

10.1101/2024.02.03.578669 — cancer biology — Posted on 2024-02-07

3625 Modeling reveals the strength of weak interactions in stacked ring assembly

Lagunes, L.; Briggs, K.; Martin-Holder, P.; Xu, Z.; Maurer, D.; Ghabra, K.; Deeds, E. J.

10.1101/2024.02.02.578706 — biophysics — Posted on 2024-02-07

3626 Sterol-lipids enable large-scale, liquid-liquid phase separation in membranes of only 2 components

Wilson, K. J.; Nguyen, H. Q.; Gervay-Hague, J.; Keller, S. L.

10.1101/2024.02.02.578692 — biophysics — Posted on 2024-02-07

3627 A coarse-grained model for disordered and multi-domain proteins

Cao, F.; von Bülow, S.; Tesei, G.; Lindorff-Larsen, K.

10.1101/2024.02.03.578735 — biophysics — Posted on 2024-02-07

3628 Plant-on-a-chip: continuous, soilless electrochemical monitoring of salt uptake and tolerance among different genotypes of tomato

Coatsworth, P.; Cotur, Y.; Asfour, T.; Zhou, Z.; Flauzino, J. M. R.; Bozkurt, T. O.; Güder, F.

10.1101/2024.02.03.578647 — bioengineering — Posted on 2024-02-07

3629 Alterations of Pleiotropic Neuropeptide-Receptor gene couples in Cetacea

Valente, R.; Cordeiro, M.; Pinto, B.; Machado, A.; Alves, F.; Sousa Pinto, I.; Ruivo, R.; Castro, L. F. C.

10.1101/2024.02.03.578746 — evolutionary biology — Posted on 2024-02-07

3630 IFNγ induces epithelial reprogramming driving CXCL11-mediated T cell migration

Cutilli, A.; Jansen, S. A.; Paolucci, F.; Mokry, M.; Mocholi, E.; Lindemans, C. A.; Coffer, P. J.

10.1101/2024.02.03.578580 — immunology — Posted on 2024-02-07

3631 The neurohormone tyramine stimulates the secretion of an Insulin-Like Peptide from the intestine to modulate the systemic stress response in C. elegans

Veuthey, T.; Giunti, S.; De Rosa, M. J.; Alkema, M. J.; Rayes, D.

10.1101/2024.02.06.579207 — neuroscience — Posted on 2024-02-07

3632 Probing PAC1 receptor activation across species with an engineered sensor

Cola, R. B.; Niethammer, S. N.; Rajamannar, P.; Gresch, A.; Bhat, M. A.; Assoumou, K.; Williams, E. T.; Hauck, P.; Hartrampf, N.; Benke, D.; Stoeber, M.; Levkowitz, G.; Melzer, S.; Patriarchi, T.

10.1101/2024.02.06.579048 — neuroscience — Posted on 2024-02-07

3633 Nandrolone alters the behavioral response to cocaine as well as striatal and cortical dopamine receptors of prepubertal male rats.

Freire-Arvelo, J. A.; Rivero, C. J.; Santiago-Marrero, I. G.; Mendez-Morales, A.; Gonzalez-Segarra, A. J.; Perez-Cardona, E. U.; Torres-Ramirez, R. J.; Segarra, A. C.

10.1101/2024.02.07.579337 — neuroscience — Posted on 2024-02-07

3634 Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy

Wahl, D.; Risen, S. J.; Osburn, S. C.; Emge, T.; Sharma, S.; Gilberto, V. S.; Chatterjee, A.; Moreno, J. A.; LaRocca, T. J.

10.1101/2024.02.03.578493 — physiology — Posted on 2024-02-07

3635 Spatial transcriptomics of healthy and fibrotic human liver at single-cell resolution

Watson, B.; Paul, B.; Amir-Zilberstein, L.; Segerstolpe, A.; Rahman, R.; Shih, A.; Deguine, J.; Xavier, R.; Moffitt, J. R.; Mullen, A. C.

10.1101/2024.02.02.578633 — genomics — Posted on 2024-02-07

3636 DNA N-gram Analysis Framework (DNAnamer): A generalized N-gram frequency analysis framework for the supervised classification of DNA sequences

Malamon, J. S.

10.1101/2024.02.02.578674 — genomics — Posted on 2024-02-07

3637 Cell Cycle-Dependent TICRR/TRESLIN and MTBP Chromatin Binding Mechanisms and Patterns

Noble, T. D.; Sansam, C. G.; Wittig, K. A.; Majchrzycka, B.; Sansam, C. L.

10.1101/2024.02.02.578516 — genomics — Posted on 2024-02-07

3638 Internal Transcribed Spacers as Phylogenetic Markers Enable Species-level Metataxonomic Analysis of Ciliated Protozoa

Somasundaram, S.; Yu, Z.

10.1101/2024.02.02.578691 — zoology — Posted on 2024-02-07

3639 Conformational Space of the Translocation Domain of Botulinum Toxin: Atomistic Modeling and Mesoscopic Description of the Coiled-Coil Helix Bundle

Delort, A.; Cottone, G.; Malliavin, T. E.; Muller, M. M.

10.1101/2024.02.02.578666 — biophysics — Posted on 2024-02-07

3640 Fine-scale genetic structure and rare variant frequencies

Gagnon, L.; Moreau, C.; Laprise, C.; Girard, S. L.

10.1101/2024.02.02.578687 — genomics — Posted on 2024-02-07

3641 Changes in responses of auditory cortex neurons upon falling asleep and awakening

Marmelshtein, A.; Lavy, B.; Hadad, B.; Nir, Y.

10.1101/2024.02.06.579189 — neuroscience — Posted on 2024-02-07

3642 Devaluation of response-produced safety signals reveals circuits for goal-directed versus habitual avoidance in dorsal striatum

Sears, R. M.; Andrade, E.; Samels, S. B.; Laughlin, L. C.; Moloney, D. M.; Wilson, D. A.; Alwood, M. R.; Moscarello, J. M.; Cain, C. K.

10.1101/2024.02.07.579321 — neuroscience — Posted on 2024-02-07

3643 Adult Neurogenesis through Glial Transdifferentiation in a CNS Injury Paradigm

Casas-Tinto, S.; Garcia-Guillen, N.; Losada-Perez, M.

10.1101/2024.02.07.579273 — neuroscience — Posted on 2024-02-07

3644 Standard rodent diets differentially impact alcohol consumption and preference and gut microbiome diversity

Zaparte, A.; Dore, E.; White, S.; Paliarin, F.; Gabriel, C.; Copenhaver, K.; Basavanhalli, S.; Garcia, E.; Vaddavalli, R.; Luo, M.; Taylor, C. M.; Welsh, D.; Maiya, R.

10.1101/2024.02.06.579237 — neuroscience — Posted on 2024-02-07

3645 Sensory Input Matching Visual Working Memory Guides Internal Prioritization

Koevoet, D.; Strauch, C.; Naber, M.; Van der Stigchel, S.

10.1101/2024.02.07.579262 — neuroscience — Posted on 2024-02-07

3646 Neuronal potassium channel activity triggers initiation of mRNA translation through binding of translation regulators

Malone, T. J.; Wu, J.; Zhang, Y.; Licznerski, P.; Chen, R.; Nahiyan, S.; Pedram, M.; Jonas, E. A.; Kaczmarek, L. K.

10.1101/2024.02.07.579306 — neuroscience — Posted on 2024-02-07

3647 Impaired response to mismatch novelty in the Li2+-pilocarpine rat model of TLE: correlation with hippocampal monoaminergic inputs

Nascimento, C.; Guerreiro-Pinto, V.; Pawlak, S.; Caulino-Rocha, A.; Amat-Garcia, L.; Cunha-Reis, D.

10.1101/2024.02.07.579299 — neuroscience — Posted on 2024-02-07

3648 Motor adaptation to environment changes predicting object behaviour can be flexible and implicit.

Modchalingam, S.; King, A.; 't Hart, B. M.; Henriques, D. Y. P.

10.1101/2024.02.06.579172 — neuroscience — Posted on 2024-02-07

3649 Striatal dopamine contributions to skilled motor learning

Phillips, C. D.; Myers, C. C.; Leventhal, D. K.; Burgess, C. R.

10.1101/2024.02.06.579240 — neuroscience — Posted on 2024-02-07

3650 Daily vocalization patterns of the Saipan Reed Warbler (Acrocephalus hiwae)

Gaul, W. B.; Lin, J.; Roark, E.

10.1101/2024.02.02.578722 — zoology — Posted on 2024-02-07

3651 Gene Regulatory Network topology governs resistance and treatment escape in glioma stem-like cells

Park, J. H.; Hothi, P.; Lopez Garcia de Lomana, A.; Pan, M.; Calder, R.; Turkarslan, S.; Wu, W.-J.; Lee, H.; Patel, A. P.; Cobbs, C.; Huang, S.; Baliga, N. S.; Baliga, N. S.

10.1101/2024.02.02.578510 — systems biology — Posted on 2024-02-07

3652 Science Education for the Youth (SEFTY): A Neuroscience Outreach Program for High School Students in Southern Nevada During the COVID-19 Pandemic

Ghani, N.; Baker, H.; Huntsinger, A.; Chen, T.; Familara, T. D.; Itorralba, J. Y.; Vanderford, F.; Zhuang, X.; Chang, C.-L.; Vo, V.; Oh, E.

10.1101/2024.02.02.578716 — scientific communication and education — Posted on 2024-02-07

3653 ATP Citrate Lyase Drives Vascular Remodeling Diseases Development Through Metabolic-Epigenetic Reprograming.

Grobs, Y.; Romanet, C.; Lemay, S.-E.; Bourgeois, A.; Voisine, P.; Theberge, C.; Sauvaget, M.; Breuils-Bonnet, S.; Martineau, S.; El-kabbout, R.; Mougin, M.; Dumais, E.; Perron, J.; Flamand, N.; Potus, F.; Provencher, S.; Boucherat, O.; Bonnet, s.

10.1101/2024.02.02.578545 — physiology — Posted on 2024-02-07

3654 Intermittent energy restriction inhibits tumor growth and enhances paclitaxel response in a transgenic mouse model of endometrial cancer

Zhao, Z.; Wang, J.; Kong, W.; Fang, Z.; Coleman, M.; Milne, G.; Burkett, W. C.; Newton, M. A.; Lee, D.; Deng, B.; Shen, X.; Suo, H.; Sun, W.; Hursting, S.; Zhou, C.; Bae-Jump, V. L.

10.1101/2024.02.02.578679 — cancer biology — Posted on 2024-02-07

3655 Commonly used software tools produce conflicting and overly-optimistic AUPRC values

Chen, W.; Miao, C.; Zhang, Z.; Fung, C. S.-H.; Wang, R.; Chen, Y.; Qian, Y.; Cheng, L.; Yip, K.; Tsui, S. K.-W.; Cao, Q.

10.1101/2024.02.02.578654 — bioinformatics — Posted on 2024-02-07

3656 Addressing the antibody germline bias and its effect on language models for improved antibody design

Olsen, T. H.; Moal, I. H.; Deane, C.

10.1101/2024.02.02.578678 — bioinformatics — Posted on 2024-02-07

3657 vmTracking: Virtual Markers Overcome Occlusion and Crowding in Multi-Animal Pose Tracking

Azechi, H.; Takahashi, S.

10.1101/2024.02.07.579241 — animal behavior and cognition — Posted on 2024-02-07

3658 Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids

Miao, Y.; Tan, C.; Pek, N. M.; Yu, Z.; Iwasawa, K.; Kechele, D. O.; Sundaram, N.; Pastrana-Gomez, V.; Kishimoto, K.; Yang, M.-c.; Jiang, C.; Tchieu, J.; Whitsett, J. A.; McCracken, K. W.; Rottier, R. J.; Kotton, D. N.; Helmrath, M. A.; Wells, J. M.; Takebe, T.; Zorn, A. M.; Chen, Y.-W.; Guo, M.; Gu, M.

10.1101/2024.02.06.577460 — developmental biology — Posted on 2024-02-07

3659 Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis

Emig, A. A.; Hansen, M.; Grimm, S. L.; Coarfa, C.; Lord, N. D.; Williams, M. K.

10.1101/2024.02.06.579243 — developmental biology — Posted on 2024-02-07

3660 Identifying the molecular basis for functional divergence of duplicated SOX factors controlling endoderm formation and left-right patterning in zebrafish

Johal, S.; Elsayed, R.; Panfilio, K. A.; Nelson, A. C.

10.1101/2024.02.06.579092 — developmental biology — Posted on 2024-02-07

3661 TPPB modulates PKC activity to attenuate neuroinflammation and ameliorate experimental multiple sclerosis

Shanmukha, S.; Godfrey, W. H.; Gharibani, P.; Lee, J. J.; Guo, Y.; Deng, X.; Wender, P. A.; Kornberg, M. D.; Kim, P. M.

10.1101/2024.02.02.578637 — immunology — Posted on 2024-02-07

3662 Transthyretin orchestrates vitamin B12-induced stress resilience

Stein, G.; Aly, J. S.; Manzolillo, A.; Lange, L.; Riege, K.; Hussain, I.; Heller, E. A.; Cubillos, S.; Ernst, T. A.; Huebner, C. A.; Turecki, G.; Hoffmann, S.; Engmann, O.

10.1101/2024.02.07.578164 — neuroscience — Posted on 2024-02-07

3663 SpiDa-MRI, behavioral and (f)MRI data of adults with fear of spiders

Zhang, M.; Karner, A.; Kostorz, K.; Shea, S.; Steyrl, D.; Melinscak, F.; Sladky, R.; Lor, C. S.; Scharnowski, F.

10.1101/2024.02.07.578564 — neuroscience — Posted on 2024-02-07

3664 Massive perturbation of sound representations by anesthesia in the auditory brainstem

Gosselin, E.; Bagur, S.; Bathellier, B.

10.1101/2024.02.06.579173 — neuroscience — Posted on 2024-02-07

3665 Lack of rhythmicity in Bmal1 deficient mice impairs motivation towards natural stimuli.

Berbegal-Saez, P.; Gallego-Landin, I.; Macia, J.; Alegre-Zurano, L.; Castro-Zavala, A.; Welz, P.-S.; Benitah, S. A.; Valverde, O.

10.1101/2024.02.07.579260 — neuroscience — Posted on 2024-02-07

3666 Effort Drives Saccade Selection

Koevoet, D.; Van Zantwijk, L.; Naber, M.; Mathot, S.; Van der Stigchel, S.; Strauch, C.

10.1101/2024.02.06.579052 — neuroscience — Posted on 2024-02-07

3667 Bidirectional emotional regulation through prefrontal innervation of the locus coeruleus

Watanabe, M.; Uematsu, A.; Johansen, J. P.

10.1101/2024.02.07.579259 — neuroscience — Posted on 2024-02-07

3668 Reversal of neuronal tau pathology, metabolic dysfunction, and electrophysiological defects via adiponectin pathway dependent AMPK activation.

McGregor, E.; Lasky, D. J.; Rippentrop, O. J.; Clark, J. P.; Wright, S. L. G.; Jones, M. V.; Anderson, R. M.

10.1101/2024.02.07.579204 — neuroscience — Posted on 2024-02-07

3669 Intra-Striatal Dopaminergic Inter-Subject Covariance in Social Drinkers and Nontreatment-Seeking Alcohol Use Disorder Participants

Chumin, E. J.; Dzemidzic, M.; Yoder, K. K.

10.1101/2024.02.06.579194 — neuroscience — Posted on 2024-02-07

3670 Genome-wide diversity in lowland and highland maize landraces from southern South America: population genetics insights to assist conservation

Dominguez, P. G.; Gutierrez, A. V.; Fass, M. I.; Filippi, C. V.; Vera, P.; Puebla, A.; Defacio, R. A.; Paniego, N. B.; Lia, V. V.

10.1101/2024.02.02.578655 — genomics — Posted on 2024-02-07

3671 Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

Wohlwend, M.; Laurila, P.-P.; Goeminne, L.; Lima, T.; Daskalaki, I.; Li, X.; von Alvensleben, G.; Crisol, B.; Mangione, R.; Gallart-Ayala, H.; Burri, O.; Butler, S.; Morris, J.; Turner, N.; Ivanisevic, J.; Auwerx, J.

10.1101/2023.08.05.552113 — physiology — Posted on 2024-02-07

3672 Cancer-associated fibroblasts reveal aberrant DNA methylation across different types of cancer

Schmidt, M.; Maie, T.; Costa, I. G.; Wagner, W.

10.1101/2024.02.02.578626 — cancer biology — Posted on 2024-02-07

3673 AttentionPert: Accurately Modeling Multiplexed Genetic Perturbations with Multi-scale Effects

Bai, D.; Ellington, C.; Mo, S.; Song, L.; Xing, E.

10.1101/2024.02.02.578656 — bioinformatics — Posted on 2024-02-07

3674 The spread of pESI-mediated extended-spectrum cephalosporin resistance in Salmonella serovars - Infantis, Senftenberg, and Alachua isolated from food animal sources in the United States

Li, C.; Tate, H.; Huang, X.; Hsu, C.-H.; Harrison, L. B.; Zhao, S.; Fortenberry, G.; Uday, D.; McDermott, P. F.; Strain, E. A.

10.1101/2024.02.02.578577 — genomics — Posted on 2024-02-07

3675 Community structure of heritable viruses in a Drosophila-parasitoids complex

Varaldi, J.; Lepetit, D.; Burlet, N.; Faber, C.; Baretje, B.; Allemand, R.

10.1101/2023.07.29.551099 — evolutionary biology — Posted on 2024-02-07

3676 Ocular dominance-dependent binocular combination of monocular neuronal responses in macaque V1

Zhang, S.-H.; Zhao, X.-N.; Tang, S.; Yu, C.

10.1101/2023.10.27.564359 — neuroscience — Posted on 2024-02-07

3677 On-farm hatching and contact with adult hen post hatch induce sex-dependent effects on performance and welfare in broiler chickens

Guilloteau, L. A.; Bertin, A.; Crochet, S.; Bagnard, C.; Hondelatte, A.; Ravon, L.; Schouler, C.; Germain, K.; Collin, A.

10.1101/2023.05.17.541117 — physiology — Posted on 2024-02-07

3678 PKSmart: An Open-Source Computational Model to Predict in vivo Pharmacokinetics of Small Molecules

Seal, S.; Trapotsi, M.-a.; Subramanian, V.; Spjuth, O.; Greene, N.; Bender, A.

10.1101/2024.02.02.578658 — bioinformatics — Posted on 2024-02-07

3679 CellCharter reveals spatial cell niches associated with tissue remodeling and cell plasticity.

Varrone, M.; Tavernari, D.; Santamaria-Martinez, A.; Walsh, L. A.; Ciriello, G.

10.1101/2023.01.10.523386 — bioinformatics — Posted on 2024-02-07

3680 Genotypic variation in resource exchange, use, and production traits in the legume-rhizobia mutualism

Calvert, M.; Hoque, M.; Wood, C. W.

10.1101/2023.08.24.554700 — evolutionary biology — Posted on 2024-02-07

3681 Sex-Specific DNA Methylation and Gene Expression Changes in Mouse Placentas After Early Preimplantation Alcohol Exposure

Legault, L.-M.; Dupas, T.; Breton-Larrivee, M.; Filion-Bienvenue, F.; Lemieux, A.; Langford-Avelar, A.; McGraw, S.

10.1101/2023.09.30.560198 — developmental biology — Posted on 2024-02-07

3682 A model for enhancer selection in dense regulatory networks captures the dynamics of cell type specification

Karin, O.

10.1101/2024.02.03.578744 — systems biology — Posted on 2024-02-07

3683 Alternative splicing of a potato disease resistance gene maintains homeostasis between development and immunity

Sun, B.; Huang, J.; Kong, L.; Gao, C.; Zhao, F.; Zhao, F.; Wang, T.; Shen, J.; Wang, L.; Wang, Y.; Halterman, D.; Dong, S.

10.1101/2023.06.09.544375 — plant biology — Posted on 2024-02-07

3684 The delayed kinetics of Myddosome formation explains why Aβ aggregates trigger TLR4 less efficiently than LPS

Li, B.; Suresh, P.; Brelstaff, J.; Kedia, S.; Bryant, C.; Klenerman, D.

10.1101/2023.09.28.559977 — biophysics — Posted on 2024-02-07

3685 OligoFormer: an accurate and robust prediction method for siRNA design

Bai, Y.; Zhong, H.; Wang, T.; Lu, Z. J.

10.1101/2024.02.02.578533 — bioinformatics — Posted on 2024-02-07

3686 A Novel, Open-Source Virtual Reality Platform for Dendritic Spine Analysis

Reimer, M. L.; Kauer, S. D.; Benson, C. A.; King, J. F.; Patwa, S.; Feng, S.; Estacion, M. A.; Bangalore, L.; Waxman, S.; Tan, A. M.

10.1101/2024.02.02.578597 — bioinformatics — Posted on 2024-02-07

3687 Optimization of liver graft function using a poly-pharmacological drug cocktail CEPT in a simulated transplant model

Kharga, A.; Mojoudi, M.; Chen, H.; Taggart, M. S.; Dinicu, A. T.; Ozgur, O. S.; Uygun, B.; Toner, M.; Tessier, S.; Yeh, H.; Markmann, J. F.; Longchamp, A.; Uygun, K.

10.1101/2024.02.02.578568 — bioengineering — Posted on 2024-02-07

3688 Transdifferentiation of Human Dental Pulp Mesenchymal Stem Cells into Spiral Ganglion-like Neurons

MESSAT, Y.; Martin-Fernandez, m.; ASSOU, S.; CHUNG, K.; Guerin, F.; Gergely, C.; Cuisinier, F.; ZINE, A.

10.1101/2024.02.02.578615 — bioengineering — Posted on 2024-02-07

3689 Meiotic drive against chromosome fusions in butterfly hybrids

Boman, J.; Wiklund, C.; Vila, R.; Backström, N.

10.1101/2024.02.02.578558 — evolutionary biology — Posted on 2024-02-07

3690 Different types of social links contrastingly shape reproductive wellbeing in a multi-level society of wild songbirds

Gokcekus, S.; Firth, J. A.; Cole, E.; Sheldon, B.; Albery, G. F.

10.1101/2024.02.02.578606 — ecology — Posted on 2024-02-07

3691 Unlocking the soundscape of coral reefs with artificial intelligence

Williams, B.; Belvanera, S. M.; Sethi, S. S.; Lamont, T. A. C.; Jompa, J.; Prasetya, M.; Richardson, L.; Weschke, E.; Hoey, A.; Beldade, R.; Mills, S. C.; Haguenauer, A.; Zuberer, F.; Simpson, S. D.; Curnick, D.; Jones, K. E.

10.1101/2024.02.02.578582 — ecology — Posted on 2024-02-07

3692 Downscaling mutualistic networks from species to individuals reveals consistent interaction niches and roles within plant populations

Quintero, E.; Arroyo-Correa, B.; Isla, J.; Rodriguez-Sanchez, F.; Jordano, P.

10.1101/2024.02.02.578595 — ecology — Posted on 2024-02-07

3693 Quick-quick-slow: the foxtrot migration and dynamic non-breeding range

Pokrovsky, I.; Curk, T.; Dietz, A.; Fufachev, I.; Kulikova, O.; Rossler, S.; Wikelski, M.

10.1101/2023.03.13.532370 — ecology — Posted on 2024-02-07

3694 Complement-Activating Multimeric Immunotherapeutic Complexes for HER2-breast cancer immunotherapy

Seguin-Devaux, C.; Brandus, B.; Plesseria, J.-M.; Iserentant, G.; Servais, J.-Y.; Kanli, G.; Behrmann, I.; Zimmer, J.; COHEN, J. H.; Dervillez, X.

10.1101/2024.02.02.578619 — immunology — Posted on 2024-02-07

3695 Optimizing Predictive Metrics for Human Language Comprehension

Sun, K.

10.1101/2023.09.03.556078 — neuroscience — Posted on 2024-02-07

3696 Comparative analysis of RNA interference and pattern-triggered immunity induced by dsRNA reveals different efficiencies in the antiviral response to Potato virus X

NECIRA, K.; Contreras, L.; Kamargiakis, S.; KAMOUN, M. S.; Canto, T.; Tenllado, F.

10.1101/2024.02.07.579064 — plant biology — Posted on 2024-02-07

3697 Chronic activation of tubulin tyrosination in HCM mice and human iPSC-engineered heart tissues improves heart function

Pietsch, N.; Chen, C. Y.; Kupsch, S.; Bacmeister, L.; Geertz, B.; Herera-Rivero, M.; Voss, H.; Krämer, E.; Braren, I.; Westermann, D.; Schlüter, H.; Mearini, G.; Schlossarek, S.; van der Velden, J.; Caporizzo, M. A.; Lindner, D.; Prosser, B. L.; Carrier, L.

10.1101/2023.05.25.542365 — physiology — Posted on 2024-02-07

3698 Energetics of the Transmembrane Peptide Sorting by Hydrophobic Mismatch

Fabian, B.; Javanainen, M.

10.1101/2024.02.02.578561 — biophysics — Posted on 2024-02-07

3699 Mechanical loading modulates AMPK and mTOR signaling in myblasts

Zhou, X.; Zhu, S.; Li, J.; Mateus, A.; Backman, L.

10.1101/2024.02.02.578567 — biophysics — Posted on 2024-02-07

3700 GraphCompass: Spatial metrics for differential analyses of cell organization across conditions

Ali, M.; Kuijs, M.; Hediyeh-zadeh, S.; Treis, T.; Hrovatin, K.; Palla, G.; Schaar, A. C.; Theis, F. J.

10.1101/2024.02.02.578605 — bioinformatics — Posted on 2024-02-07

3701 Nutritional sex-specificity on bacterial metabolites during mosquito development leads to adult sex-ratio distortion

Romoli, O.; Serrato-Salas, J.; Gapp, C.; Epelboin, Y.; Figueras Ivern, P.; Barras, F.; Gendrin, M.

10.1101/2023.10.18.562973 — developmental biology — Posted on 2024-02-07

3702 Evaporation of bacteria-laden surrogate respiratory fluid droplets: On a hydrophilic substrate versus contact-free environment confers differential bacterial infectivity

Agharkar, A. N.; Hajra, D.; Roy, D.; Jaiswal, V.; Kabi, P.; Chakravortty, D.; Basu, S.

10.1101/2024.01.17.576159 — microbiology — Posted on 2024-02-07

3703 A new family of statistical tests for neuronal spiking and autocorrelated timeseries data

Montijn, J. S.; Meijer, G. T.; Heimel, J. A.

10.1101/2023.10.30.564780 — neuroscience — Posted on 2024-02-07

3704 Tree Species as Biomonitors of Air Pollution around a Scrap Metal Recycling Factory in Southwest Nigeria: Implications for Greenbelt Development

Olanipon, D. G.; Ayandeyi, K. F.; Enochoghene, A. E.; Eludoyin, A.; Adanikin, B.; Awotoye, O.

10.1101/2024.02.06.579208 — plant biology — Posted on 2024-02-07

3705 Analysis of multi-condition single-cell data with latent embedding multivariate regression

Ahlmann-Eltze, C.; Huber, W.

10.1101/2023.03.06.531268 — bioinformatics — Posted on 2024-02-07

3706 A Comprehensive Benchmarking Study on Computational Tools for Cross-omics Label Transfer from Single-cell RNA to ATAC Data

Wang, Y.; Zhao, H.

10.1101/2024.02.01.578507 — genomics — Posted on 2024-02-07

3707 Don't Leave the Past Behind: How Larval Experience Shapes Pupal Antipredator Response in Aedes aegypti

Rawat, K.; Bhambore, A. A.; Isvaran, K.

10.1101/2024.02.02.578532 — ecology — Posted on 2024-02-07

3708 Pial collaterals develop through mosaic colonization of capillaries by arterial and microvascular endothelial cells

Perovic, T.; Hollfinger, I.; Mayer, S.; Lips, J.; Dopatka, M.; Harms, C.; Gerhardt, H.

10.1101/2023.10.09.561542 — developmental biology — Posted on 2024-02-07

3709 Single-nucleus RNA sequencing reveals cellular and molecular dynamics of white and brown adipose tissue in a mouse model of type-2 diabetes

Gaynor, T. L.; Hsu, I.; Krstevski, C.; Farrugia, G. E.; Dona, M. S.; Cohen, C. D.; Drew, B. G.; Pinto, A. R.

10.1101/2024.02.06.578860 — cell biology — Posted on 2024-02-07

3710 A ZBP1 isoform blocks ZBP1-mediated cell death

Cai, Z.-Y.; Wu, P.; Mo, W.; Yang, Z.-H.

10.1101/2024.02.02.578522 — immunology — Posted on 2024-02-07

3711 Osteochondroprogenitor cells and neutrophils expressing p21 and senescence markers modulate fracture repair

Saul, D.; Doolittle, M. L.; Rowsey, J. L.; Froemming, M. N.; Kosinsky, R. L.; Vos, S. J.; Ruan, M.; LeBrasseur, N.; Chandra, A.; Pignolo, R.; Passos, J.; Farr, J. N.; Monroe, D.; Khosla, S.

10.1101/2024.02.01.578420 — physiology — Posted on 2024-02-07

3712 Safety, pharmacokinetics, and potential neurological interactions of ivermectin, tafenoquine and chloroquine in Rhesus Macaques

Vanachayangkul, P.; Kodchakorn, C.; Ta-aksorn, W.; Im-Erbsin, R.; Tungtaeng, A.; Tipthara, P.; Tarning, J.; Lugo-Roman, L. A.; Wojnarski, M.; Vesely, B. A.; Kobylinski, K. C.

10.1101/2024.02.01.578449 — pharmacology and toxicology — Posted on 2024-02-07

3713 An image segmentation pipeline optimized for human microglia uncovers sources of morphological diversity in Alzheimer's disease

De Jager, R. M.; Lee, A. J.; Sigalov, A.; Taga, M.

10.1101/2024.02.01.577128 — pathology — Posted on 2024-02-07

3714 SELECTIVE EPITHELIAL ACTIVATION OF KRASG12D DRIVES DUCTAL PANCREATIC NEOPLASIA IN SWINE

Jara, C. P.; Al-Gahmi, A.-M.; Carlson, M. A.

10.1101/2024.02.01.578513 — cancer biology — Posted on 2024-02-07

3715 Microtubule polymerization tuned by macromolecular crowdant size and density

Basu, J.; Soni, A.; Athale, C. A.

10.1101/2024.02.02.578534 — biophysics — Posted on 2024-02-07

3716 Cerebra: a computationally efficient framework for accurate protein structure prediction

Hu, J.; Wang, W.; Gong, H.

10.1101/2024.02.02.578551 — bioinformatics — Posted on 2024-02-07

3717 Generating single-cell gene expression profiles for high-resolution spatial transcriptomics based on cell boundary images

Zhang, B.; Li, M.; Kang, Q.; Deng, Z.; Qin, H.; Su, K.; Feng, X.; Chen, L.; Liu, H.; Fang, S.; Zhang, Y.; Li, Y.; Brix, S.; Xu, X.

10.1101/2023.12.25.573324 — bioinformatics — Posted on 2024-02-07

3718 Efficient stripe artefact removal by a variational method: application to light-sheet microscopy, FIB-SEM and remote sensing images

Rottmayer, N.; Redenbach, C.; Fahrbach, F.

10.1101/2024.02.02.578531 — bioengineering — Posted on 2024-02-07

3719 Persistent tailoring of MSC activation through genetic priming

Beauregard, M. A.; Bedford, G. C.; Brenner, D. A.; Sanchez Solis, L. D.; Nishiguchi, T.; Abhimanyu, ; Carrero Longlax, S.; Mahata, B.; Veiseh, O.; Wenzel, P. L.; DiNardo, A. R.; Hilton, I. B.; Diehl, M. R.

10.1101/2024.02.01.578489 — bioengineering — Posted on 2024-02-07

3720 Biochemical fractionation of human α-Synuclein in a Drosophila model of synucleinopathies

Imomnazarov, K.; Lopez-Scarim, J.; Bagheri, I.; Joers, V.; Tansey, M. G.; Martin-Pena, A.

10.1101/2024.02.05.579034 — biochemistry — Posted on 2024-02-07

3721 Effects of inbreeding and elevated rearing temperatures on strategic sperm production

Chung, M.-H.; Mahmud-Al-Hasan, M.; Jennions, M. D.; Head, M. L.

10.1101/2024.02.01.578518 — evolutionary biology — Posted on 2024-02-07

3722 Stimulated Prorocentrum donghaiense cell growth by in-situ mariculture dissolved organic matter

Wang, H.; Wu, S.; Ma, J.; Hong, Y.; Guo, C.; Zhao, J.; Lin, X.

10.1101/2024.02.02.578562 — ecology — Posted on 2024-02-07

3723 Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

Sim, M. J. W.; Hanada, K.-i.; Stotz, Z. S.; Yu, Z.; Lu, J.; Brennan, P.; Quastel, M.; Gillespie, G.; Long, E. O.; Yang, J. C.; Sun, P. D.

10.1101/2024.02.01.578367 — immunology — Posted on 2024-02-07

3724 Multiomic ALS signatures highlight sex differences and molecular subclusters and identify the MAPK pathway as therapeutic target

10.1101/2023.08.14.553180 — neuroscience — Posted on 2024-02-07

3725 gMCSpy: Efficient and accurate computation of Genetic Minimal Cut Sets in Python

Rodriguez, C. J.; Barrena, N.; Olaverri-Mendizabal, D.; Ochoa, I.; Valcarcel, L. V.; Planes, F. J.

10.1101/2024.02.02.578370 — systems biology — Posted on 2024-02-07

3726 The Non-Phototrophic Hypocotyl3 (NPH3)-domain protein NRL5 is a trafficking-associated GTPase essential for drought resistance.

UPADHYAY-TIWARI, N.; Huang, X.-J.; Lee, Y.-C.; Singh, S. K.; Hsu, C.-C.; Huang, S.-S.; Verslues, P. E.

10.1101/2023.05.10.540297 — plant biology — Posted on 2024-02-07

3727 Mesenchymal stem cell-derived extracellular vesicles attenuate symptoms in dextran sodium sulfate-induced ulcerative colitis mouse model

Zhai, Y.; Liu, G.; Cui, C.; Yi, Y.; Yan, Y.; Zhang, L.; Wang, W.; He, X.; Xu, K.

10.1101/2024.02.01.578325 — physiology — Posted on 2024-02-07

3728 Single cell transcriptome analysis of cavernous tissues reveals the key roles of pericytes in diabetic erectile dysfunction

Bae, S.-G.; Yin, G.-N.; Ock, J.; Suh, J.-K.; Ryu, J.-K.; Park, J.

10.1101/2023.05.25.542355 — bioinformatics — Posted on 2024-02-07

3729 WildPose: A Long-Range 3D wildlife motion capture system

Muramatsu, N.; Shin, S.; Deng, Q.; Markham, A.; Patel, A.

10.1101/2024.02.05.578861 — animal behavior and cognition — Posted on 2024-02-07

3730 The simplicity of protein sequence-function relationships

Park, Y.; Metzger, B. P. H.; Thornton, J. W.

10.1101/2023.09.02.556057 — genetics — Posted on 2024-02-07

3731 Before and after delisting: population dynamics of North Atlantic humpback whales over two decades in the Gulf of Maine

Robbins, J.; Berube, M.; Clapham, P. J.; Mattila, D. K.; Palsboll, P. J.; Asmutis-Silvia, R.; Hill, A.; Howes, L. J.; Landry, S.; Lonergan, S.; Schulte, D.; Tackaberry, J. E.; Weinrich, M. T.; Pace, R. M.

10.1101/2024.02.04.577870 — ecology — Posted on 2024-02-07

3732 Flexible foraging behaviour increases predator vulnerability to climate change

Gauzens, B.; Rosenbaum, B.; Kalinkat, G.; Boy, T.; Jochum, M.; Kortsch, S.; O'Gorman, E. J.; Brose, U.

10.1101/2021.05.05.442768 — ecology — Posted on 2024-02-07

3733 Visualizing sarcomere and cellular dynamics in skeletal muscle to improve cell therapies

Hüttemeister, J.; Rudolph, F.; Radke, M.; Fink, C.; Friedrich, D.; Preibisch, S.; Falcke, M.; Wagner, E.; Lehnart, S. E.; Gotthardt, M.

10.1101/2024.02.01.578471 — cell biology — Posted on 2024-02-07

3734 Turnover of PPP1R15A mRNA encoding GADD34 controls the molecular memory of the cellular integrated stress response

Magg, V.; Manetto, A.; Kopp, K.; Wu, C. C.; Naghizadeh, M.; Lindner, D.; Eke, L.; Welsch, J.; Kallenberger, S. M.; Schott, J.; Haucke, V.; Locker, N.; Stoecklin, G.; Ruggieri, A.

10.1101/2023.11.11.566686 — cell biology — Posted on 2024-02-07

3735 Skeletal muscle hypertrophy rewires glucose metabolism: an experimental investigation and systematic review

Baumert, P.; Mantyselka, S.; Schoenfelder, M.; Heiber, M.; Jacobs, M. J.; Swaminathan, A.; Minderis, P.; Dirmontas, M.; Kleigrewe, K.; Meng, C.; Gigl, M.; Ahmetov, I. I.; Venckunas, T.; Degens, H.; Ratkevicius, A.; Hulmi, J.; Wackerhage, H.

10.1101/2022.12.08.519580 — molecular biology — Posted on 2024-02-07

3736 Reconceptualizing programmed transcriptional slippage in RNA viruses

Valli, A. A.; Domingo-Calap, M. L.; Gonzalez de Pradena, A.; Garcia, J. A.; Cui, H.; Desbiez, C.; Lopez-Moya, J. J.

10.1101/2024.02.05.578984 — molecular biology — Posted on 2024-02-07

3737 Limit of detection of Salmonella ser. Enteritidis using culture-based versus culture-independent diagnostic approaches

Bradford, L. M.; Yao, L.; Anastasiadis, C.; Cooper, A. L.; Blais, B.; Deckert, A. E.; Reid-Smith, R. J.; Lau, C. H.-F.; Diarra, M. S.; Carrillo, C.; Wong, A.

10.1101/2024.02.05.578949 — microbiology — Posted on 2024-02-07

3738 Temperatures above 37°C increase virulence of a convergent Klebsiella pneumoniae sequence type 307 strain

Mueller, J. U.; Schwabe, M.; Swiatek, L.-S.; Heiden, S. E.; Schlüter, R.; Sittner, M.; Bohnert, J. A.; Becker, K.; Idelevich, E. A.; Guenther, S.; Eger, E.; Schaufler, K.

10.1101/2024.02.06.579160 — microbiology — Posted on 2024-02-07

3739 Hypermigration of macrophages through the concerted action of GRA effectors on NF-κB/p38 signaling and host chromatin accessibility potentiates Toxoplasma dissemination

ten Hoeve, A. L.; Rodriguez, M. E.; Säflund, M.; Michel, V.; Magimel, L.; Ripoll, A.; Yu, T.; Hakimi, M.-A.; Saeij, J. P.; Ozata, D. M.; Barragan, A.

10.1101/2024.02.06.579146 — microbiology — Posted on 2024-02-07

3740 Effects of excess phosphate on a coastal plankton community

Spilling, K.; Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Labrenz, M.; Grossart, H.-P.; Piwosz, K.

10.1101/2024.02.05.576994 — microbiology — Posted on 2024-02-07

3741 DBT is a metabolic switch for maintenance of proteostasis under proteasomal impairment

Hwang, R.-D.; Lu, Y.; Tang, Q.; Periz, G.; Park, G.; Li, X.; Liu, Y.; Zhang, T.; Wang, J.

10.1101/2023.09.12.556394 — neuroscience — Posted on 2024-02-07

3742 Predictive processing in biological motion perception: Evidence from human behavior

Elmas, H. O.; Er, S.; Rezaki, A. D.; Izgi, A.; Urgen, B. M.; Boyaci, H.; Urgen, B. A.

10.1101/2024.02.03.578729 — neuroscience — Posted on 2024-02-07

3743 αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

10.1101/2024.02.06.578742 — cancer biology — Posted on 2024-02-07

3744 Identification of Potential EGFR Inhibitors for Type 2 Diabetes and Pancreatic Cancer Treatment: A Computational Approach

Romero, R.

10.1101/2023.09.05.556125 — bioinformatics — Posted on 2024-02-07

3745 A learned score function improves the power of mass spectrometry database search

Ananth, V.; Sanders, J.; Yilmaz, M.; Oh, S.; Noble, W. S.

10.1101/2024.01.26.577425 — bioinformatics — Posted on 2024-02-07

3746 A long-context language model for deciphering and generating bacteriophage genomes

Shao, B.

10.1101/2023.12.18.572218 — bioinformatics — Posted on 2024-02-07

3747 NAVIP: Unraveling the Influence of Neighboring Small Sequence Variants on Functional Impact Prediction

Baasner, J.-S.; Rempel, A.; Howard, D.; Pucker, B.

10.1101/596718 — genomics — Posted on 2024-02-07

3748 Trans-eQTL mapping in gene sets identifies network effects of genetic variants

Wang, L.; Babushkin, N.; Liu, Z.; Liu, X.

10.1101/2022.11.11.516189 — genetics — Posted on 2024-02-07

3749 Cell cycle perturbation uncouples mitotic progression and invasive behavior in a post-mitotic cell

Martinez, M. A. Q.; Zhao, C.; Moore, F. E. Q.; Yee, C. S.; Zhang, W.; Shen, K.; Martin, B. L.; Matus, D. Q.

10.1101/2023.03.16.533034 — developmental biology — Posted on 2024-02-07

3750 Characterization Of Bitter Taste Receptor Dependent Autophagy in Oral Epithelial Cells

Singh, N.; Ghavami, S.; Chelikani, P.

10.1101/2024.02.02.578576 — cell biology — Posted on 2024-02-07

3751 ChAHP2 and ChAHP control diverse retrotransposons by complementary activities

Ahel, J.; Pandey, A.; Schwaiger, M.; Mohn, F.; Basters, A.; Kempf, G.; Andriollo, A.; Kaaij, L.; Hess, D.; Bühler, M.

10.1101/2024.02.05.578923 — molecular biology — Posted on 2024-02-07

3752 Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome

Ranum, J. N.; Ledwith, M. P.; Alnaji, F. G.; Diefenbacher, M.; Orton, R.; Sloan, E.; Guereca, M.; Feltman, E. M.; Smollett, K.; da Silva Filipe, A.; Conley, M.; Russell, A. B.; Brooke, C. B.; Hutchinson, E.; Mehle, A.

10.1101/2023.12.12.570638 — microbiology — Posted on 2024-02-07

3753 Transposon mutagenesis screen in Klebsiella pneumoniae identifies genetic determinants required for growth in human urine and serum

Gray, J.; Torres, V. V. L.; Goodall, E. C.; McKeand, S. A.; Scales, D.; Collins, C.; Wetherall, L.; Lian, Z. J.; Bryant, J. A.; Milner, M. T.; Dunne, K.; Icke, C.; Rooke, J.; Schneiders, T.; Lund, P. A.; Cunningham, A. F.; Cole, J. A.; Henderson, I. R.

10.1101/2023.05.31.543172 — microbiology — Posted on 2024-02-07

3754 Analytical strength-duration curve for the spiking response of the LIF neuron to an alpha-function-shaped excitatory current pulse

Paraskevov, A.

10.1101/2023.09.05.556358 — neuroscience — Posted on 2024-02-07

3755 Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation

Elum, J. E.; Szelenyi, E. R.; Juarez, B.; Murry, A. D.; Loginov, G.; Zamorano, C. A.; Gao, P.; Wu, G.; Ng-Evans, S.; Xu, X.; Golden, S. A.; Zweifel, L. S.

10.1101/2024.02.05.578997 — neuroscience — Posted on 2024-02-07

3756 Predictive Sequence Learning in the Hippocampal Formation

Chen, Y.; Zhang, H.; Cameron, M.; Sejnowski, T. J.

10.1101/2022.05.19.492731 — neuroscience — Posted on 2024-02-07

3757 Neural specialization for 'visual' concepts emerges in the absence of vision

Hauptman, M.; Elli, G.; Pant, R.; Bedny, M.

10.1101/2023.08.23.552701 — neuroscience — Posted on 2024-02-07

3758 Brain-state mediated modulation of inter-laminar dependencies in visual cortex

Das, A.; Sheffield, A. G.; Nandy, A. S.; Jadi, M. P.

10.1101/2023.02.04.527119 — neuroscience — Posted on 2024-02-07

3759 Cellular distribution and motion of essential magnetosome proteins expressed in mammalian cells

Sun, Q.; Fradin, C.; Thompson, R. T.; Prato, F. S.; Goldhawk, D. E.

10.1101/2023.12.19.572414 — synthetic biology — Posted on 2024-02-07

3760 A dose-response model for statistical analysis of chemical genetic interactions in CRISPRi screens

Choudhery, S.; DeJesus, M.; Srinivasan, A.; Rock, J.; Schnappinger, D.; Ioerger, T.

10.1101/2023.08.03.551759 — bioinformatics — Posted on 2024-02-07

3761 Untargeted Pixel-by-Pixel Imaging of Metabolite Ratio Pairs as a Novel Tool for Biomedical Discovery in Mass Spectrometry Imaging

Cheng, H.; Miller, D.; Southwell, N.; Fischer, J.; Taylor, I.; Salbaum, M.; Kappen, C.; Hu, F.; Yang, C.; Gross, S.; D'Aurelio, M.; Chen, Q.

10.1101/2024.01.10.575105 — bioinformatics — Posted on 2024-02-07

3762 Tradeoffs in Modeling Context Dependency in Complex Trait Genetics

Weine, E.; Smith, S. P.; Knowlton, R. K.; Harpak, A.

10.1101/2023.06.21.545998 — genomics — Posted on 2024-02-07

3763 Mutualism provides the basis for biodivesity in eco-evolutionary community assembly

Araujo, G.; Lurgi, M.

10.1101/2024.02.02.578708 — ecology — Posted on 2024-02-07

3764 DNA density is a better indicator of a nuclear bleb than lamin B loss

Bunner, S.; Prince, K.; Srikrishna, K.; Pujadas, E. M.; Pellegrino, P.; Aiello, J.; McCarthy, A. A.; Lawlor, C.; Jagtap, S.; Kuklinski, A.; Yas, G.; LaPointe, N.; Eweka, I.; Eastin, E.; Jackson, O.; Chen, J.; Schramm von Blucher, I.; Hardy, J.; Backman, V.; Janssen, A.; Packard, M.; Dorfman, K.; Almassalha, L.; Bahiru, M. S.; Stephens, A. D.

10.1101/2024.02.06.579152 — cell biology — Posted on 2024-02-07

3765 Networked proteins redundantly interact with VAP27 and RABG3 to regulate membrane tethering at the vacuole and beyond

Kaiser, S.; Mehlhorn, D.; Ramirez Miranda, P.; Ries, F.; Sommer, F.; Schroda, M.; Schumacher, K.; Willmund, F.; Grefen, C.; Scheuring, D.

10.1101/2023.09.29.560113 — cell biology — Posted on 2024-02-07

3766 Affinity-tagged SMAD1 and SMAD5 mouse lines reveal transcriptional reprogramming mechanisms during early pregnancy

Liao, Z.; Tang, S.; Nozawa, K.; Shimada, K.; Ikawa, M.; Monsivais, D.; Matzuk, M.

10.1101/2023.09.25.559321 — molecular biology — Posted on 2024-02-07

3767 Small Molecule G-quadruplex Ligands are Antibacterial Candidates for Gram-negative Bacteria

Takebayashi, Y.; Ramos-Soriano, J.; Jiang, Y. J.; Samphire, J.; Belmonte-Reche, E.; O'Hagan, M. P.; Gurr, C.; Heesom, K. J.; Lewis, P. A.; Samernate, T.; Nonejuie, P.; Spencer, J.; Galan, M. C.

10.1101/2022.09.01.506212 — microbiology — Posted on 2024-02-07

3768 Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature

Abiega, O.; Senovilla-Ganzo, R.; El-Ouraoui, M.; Muro Garcia, T.; Ruiz Clavijo, L.; Garcia Moreno, F.; Fitzsimons, C. P.; Martin Suarez, S.; Encinas Perez, J. M.

10.1101/2024.01.26.577346 — neuroscience — Posted on 2024-02-07

3769 Convergent mutations and single nucleotide variants in mitochondrial genomes of modern humans and Neanderthals

Ferreira, R. C.; Rodrigues, C. R.; Broach, J. R.; Briones, M. R.

10.1101/190363 — genomics — Posted on 2024-02-07

3770 Distinct patterns of genetic variation at low-recombining genomic regions represent haplotype structure

10.1101/2021.12.22.473882 — evolutionary biology — Posted on 2024-02-07

3771 Detecting adaptive changes in gene copy number distribution accompanying the human out-of-Africa expansion

Otto, M.; Zheng, Y.; Grablowitz, P.; Wiehe, T.

10.1101/2023.08.14.553171 — evolutionary biology — Posted on 2024-02-07

3772 Protein-protein interactions with G3BPs drive stress granule condensation and gene expression changes under cellular stress

Liboy-Lugo, J. M.; Espinoza, C. A.; Sheu-Gruttadauria, J.; Park, J. E.; Xu, A.; Jowhar, Z.; Gao, A. L.; Carmona-Negron, J. A.; Wittmann, T.; Jura, N.; Floor, S. N.

10.1101/2024.02.06.579149 — cell biology — Posted on 2024-02-07

3773 Brain-heart dynamics during emotional processing under uncertain conditions: An index of depression risk

Chan, H.-L.; Kanayama, N.; Mizuochi, R.; Yamawaki, S.; Machizawa, M. G.

10.1101/2021.12.06.471520 — neuroscience — Posted on 2024-02-07

3774 Task dependent coarticulation of movement sequences

Kalidindi, H. T.; Crevecoeur, F.

10.1101/2023.12.15.571847 — neuroscience — Posted on 2024-02-07

3775 Dynamic corticothalamic modulation of the somatosensory thalamocortical circuit during wakefulness

Dimwamwa, E.; Pala, A.; Chundru, V.; Wright, N. C.; Stanley, G. B.

10.1101/2023.07.18.549491 — neuroscience — Posted on 2024-02-07

3776 Speech-induced suppression and vocal feedback sensitivity in human cortex

Ozker, M.; Yu, L.; Dugan, P.; Doyle, W.; Friedman, D.; Devinsky, O.; Flinker, A.

10.1101/2023.12.08.570736 — neuroscience — Posted on 2024-02-07

3777 Causal role of the angular gyrus in insight-driven memory reconfiguration

Grob, A.-M.; Heinbockel, H.; Milivojevic, B.; Doeller, C.; Schwabe, L.

10.1101/2023.08.18.553803 — neuroscience — Posted on 2024-02-07

3778 A non-image-forming visual circuit mediates the innate fear of heights

Shang, W.; Xie, S.; Feng, W.; Li, Z.; Jia, J.; Cao, X.; Shen, Y.; Li, J.; Shi, H.; Gu, Y.; Weng, S.-J.; Lin, L.; Pan, Y.-H.; Yuan, X.

10.1101/2023.05.27.542556 — neuroscience — Posted on 2024-02-07

3779 Exploring the metabolic profiling of A. baumannii for antimicrobial development using genome-scale modeling

Leonidou, N.; Xia, Y.; Friedrich, L.; Schuetz, M.; Draeger, A.

10.1101/2023.09.13.557502 — systems biology — Posted on 2024-02-07

3780 Global regulators facilitate adaptation to a phenotypic trade-off

Deyell, M.; Opuu, V.; Griffiths, A. D.; Tans, S.; Nghe, P.

10.1101/2023.09.19.558433 — systems biology — Posted on 2024-02-07

3781 Continuity of Mitochondrial Budding: Insights from BS-C-1 Cells by in-situ Cryo-Electron Tomography

Hu, J. Z.; Qiao, L.; Zhao, X.; Liu, C.-J.; Hu, G.

10.1101/2023.11.10.566563 — biophysics — Posted on 2024-02-07

3782 The BTB-ZF gene Bm-mamo regulates pigmentation in silkworm caterpillars

Wu, S.; Tong, X.; Peng, C.; Luo, J.; Zhang, C.; Lu, K.; Li, C.; Ding, X.; Duan, X.; Lu, Y.; Hu, H.; Tan, D.; Dai, F.

10.1101/2023.04.07.536007 — genetics — Posted on 2024-02-07

3783 The genome sequence of the Montseny horsehair worm, Gordionus montsenyensis sp. nov., a key resource to investigate Ecdysozoa evolution

Eleftheriadi, K.; Guiglielmoni, N.; Salces-Ortiz, J.; Vargas-Chavez, C.; Martinez-Redondo, G. I.; Gut, M.; Flot, J.-F.; Schmidt-Rhaesa, A.; Fernandez, R.

10.1101/2023.06.26.546503 — evolutionary biology — Posted on 2024-02-07

3784 Highly dynamic evolution of the chemosensory gene repertoire driven by gene gain and expansion across subterranean beetles

Balart-Garcia, P.; Bradford, T. M.; Beasley-Hall, P. G.; Polak, S.; Ribera, I.; Cooper, S. J.; Fernandez, R.

10.1101/2022.12.08.519422 — evolutionary biology — Posted on 2024-02-07

3785 Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

Xue, Y.; Zhou, Y.; Cepko, C. L.

10.1101/2023.08.03.551766 — molecular biology — Posted on 2024-02-07

3786 Hiding in Plain Sight: Thymic CD8+FOXP3+Tregs sequester CD25 and are enriched in human tissues

Jarvis, L. B.; Howlett, S. K.; Coppard, V. B.; Rainbow, D. B.; Alkwai, S. B.; Ellis, L. B.; Georgieva, Z. B.; Suchanek, O. B.; Mousa, H. S.; Mahbubani, K. T.; Saeb-Parsy, K. B.; Wicker, L. S.; Jones, J. L.

10.1101/2023.12.24.573232 — immunology — Posted on 2024-02-07

3787 Representational drift as a result of implicit regularization

Ratzon, A.; Derdikman, D.; Barak, O.

10.1101/2023.05.04.539512 — neuroscience — Posted on 2024-02-07

3788 mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction

Joshi, J.; Lerner, A.; Scallo, F.; Grumet, A.; Matteson, P.; Millonig, J.; Valvezan, A.

10.1101/2024.02.06.579216 — molecular biology — Posted on 2024-02-07

3789 Ramping dynamics in the frontal cortex unfold over multiple timescales during motor planning

Affan, R. O.; Bright, I. M.; Pemberton, L.; Cruzado, N. A.; Scott, B. B.; Howard, M. O.

10.1101/2024.02.05.578819 — neuroscience — Posted on 2024-02-06

3790 PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis

Liu, G.; Hou, Y.; Jin, X.; Zhang, Y.; Sun, C.; Huang, C.; Ren, Y.; Gao, J.; Wang, X.; Jiang, X.

10.1101/2024.02.05.578960 — molecular biology — Posted on 2024-02-06

3791 A deterministic, c-di-GMP-dependent genetic program ensures the generation of phenotypically similar, symmetric daughter cells during cytokinesis

Perez-Burgos, M.; Herfurth, M.; Kaczmarczyk, A.; Harms, A.; Huber, K.; Jenal, U.; Glatter, T.; Sogaard-Andersen, L.

10.1101/2024.02.06.579105 — microbiology — Posted on 2024-02-06

3792 Enhanced Sequence-Activity Mapping and Evolution of Artificial Metalloenzymes by Active Learning

Vornholt, T.; Mutny, M.; Schmidt, G. W.; Schellhaas, C.; Tachibana, R.; Panke, S.; Ward, T. R.; Krause, A.; Jeschek, M.

10.1101/2024.02.06.579157 — synthetic biology — Posted on 2024-02-06

3793 Towards a Survival Risk Prediction Model for Metastatic NSCLC Patients on Durvalumab Using Whole-Lung CT Radiomics

Patwardhan, K. A.; RaviPrakash, H.; Nikolaou, N.; Gonzalez-Garcia, I.; Salazar, J. D.; Metcalfe, P.; Reischl, J.

10.1101/2024.02.01.578458 — bioinformatics — Posted on 2024-02-06

3794 Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function

Jang, G. M.; Sudarsan, A. K. A.; Shayeganmehr, A.; Munhoz, E. P.; Lao, R.; Gaba, A.; Rodriguez, M. G.; Love, R. P.; Polacco, B. J.; Zhou, Y.; Krogan, N. J.; Kaake, R. M.; Chelico, L.

10.1101/2024.02.06.579137 — biochemistry — Posted on 2024-02-06

3795 Self-regulation of the DNA N6-adenine methyltransferase AMT1 in the unicellular eukaryote Tetrahymena thermophila

Duan, L.; Li, H.; Ju, A.; Zhang, Z.; Niu, J.; Zhang, Y.; Diao, J.; Kataoka, K.; Ma, H.; Song, N.; Gao, S.; Wang, Y.

10.1101/2024.02.06.579081 — genetics — Posted on 2024-02-06

3796 Environmental DNA from ethanol eluent of flowers reveals a widespread diversity in cowpea associated animal communities in Hainan Island

Chen, Q.; Yu, H.-L.; Lv, J.-X.; Wang, X.; Li, J.; Wu, M.-Y.; Shi, C.-H.; Xie, W.; Kong, X.-Y.; Huang, G.-H.

10.1101/2024.02.01.578371 — ecology — Posted on 2024-02-06

3797 Toward Sustainable Biocultural Tourism: An Integrated Spatial Analysis of Cultural and Biodiversity Richness in Colombia

Echeverri, A.; Batista, N. M.; Wolny, S.; Herrera-R, G. A.; Andrade-Rivas, F.; Bailey, A.; Cardenas-Navarrete, A.; Davila-Arenas, A.; Diaz-Salazar, A. F.; Hernandez, K. V.; Langhans, K. E.; Mateus Aguilar, B. E.; Levey, D. R.; Neill, A.; Nguyen, O.; Suarez-Castro, A. F.; Zapata, F.; Ocampo-Penuela, N.

10.1101/2024.02.01.578429 — ecology — Posted on 2024-02-06

3798 The global root exudate carbon flux

Chari, N. R.; Tumber-Davila, S. J.; Phillips, R. P.; Bauerle, T. L.; Brunn, M.; Hafner, B. D.; Klein, T.; Obersteiner, S.; Reay, M. K.; Ullah, S.; Taylor, B. N.

10.1101/2024.02.01.578470 — ecology — Posted on 2024-02-06

3799 Introducing synthetic thermostable RNase inhibitors to single-cell RNA-seq

Noble, J. C.; Lentini, A.; Hageman-Jensen, M.; Sandberg, R.; Reinius, B.

10.1101/2024.02.06.579116 — molecular biology — Posted on 2024-02-06

3800 Deciphering Staphylococcus aureus-host dynamics using dual activity-based protein profiling of ATP-interacting proteins

Ahator, S. D.; Hegstad, K.; Lentz, C. S.; Johannessen, M.

10.1101/2024.02.05.578939 — molecular biology — Posted on 2024-02-06

3801 YraN is a helicase-associated nuclease fostering extended recombination events by natural transformation

Hardy, L.; Plantade, J.; Morales, V.; Mazzamurro, F.; Rocha, E. P. C.; Polard, P.; Charpentier, X.

10.1101/2024.02.06.579203 — microbiology — Posted on 2024-02-06

3802 Proteolytic control of FixT by the Lon protease impacts FixLJ signaling in Caulobacter crescentus

Yigit, K.; Chien, P.

10.1101/2024.02.05.579008 — microbiology — Posted on 2024-02-06

3803 Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection

Adams, L.; Li, X.; Burchmore, R.; Goodwin, R.; Wall, D. M.

10.1101/2024.02.06.579072 — microbiology — Posted on 2024-02-06

3804 Assessing NGS-based computational methods for predicting transcriptional regulators with query gene sets

Lu, Z.; Xiao, X.; Zheng, Q.; Wang, X.; Xu, L.

10.1101/2024.02.01.578316 — bioinformatics — Posted on 2024-02-06

3805 The MYCN oncoprotein and helicases DDX17 and DDX5 have opposite effects on the production of chimeric transcripts in neuroblastoma cells

Clerc, V.; Valat, J.; Grand, X.; Fontrodona, N.; Bazire, M.; Rama, N.; Auboeuf, D.; Gibert, B.; Mortreux, F.; Bourgeois, C. F.

10.1101/2024.02.05.578895 — molecular biology — Posted on 2024-02-06

3806 A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis

Chauhan, K.; Passricha, N.; Kapoor, Y.; Datta, D.; Arora, N.; Das, M.; Rao, K.; Singh, L.; Dutt, R.; Sharma, R.; Sarkar, B.; Malakkar, B.; Kalam, H.; Saini, P.; Mehra, L.; Das, P.; Ahuja, V.; Singhal, A.; Nandicoori, V.; Kumar, D.

10.1101/2024.02.06.579120 — molecular biology — Posted on 2024-02-06

3807 A 20-year time-series of a freshwater lake reveals seasonal dynamics and environmental drivers of viral diversity, ecology, and evolution

Zhou, Z.; Tran, P. Q.; Martin, C.; Rohwer, R. R.; Baker, B.; McMahon, K.; Anantharaman, K.

10.1101/2024.02.06.579183 — microbiology — Posted on 2024-02-06

3808 Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1

Griffith, S.; Muir, L.; Suchanek, O.; Hope, J.; Pade, C.; Gibbons, J. M.; Tuong, Z. K.; Fung, A.; Touizer, E.; Rees-Spear, C.; Nans, A.; Roustan, C.; Alguel, Y.; Fink, D.; Orkin, C.; Deayton, J.; Anderson, J.; Gupta, R. K.; Doores, K. J.; Cherepanov, P.; McKnight, A.; Clatworthy, M.; McCoy, L. E.

10.1101/2024.02.05.578789 — microbiology — Posted on 2024-02-06

3809 Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex

Carr, C. R.; Crawford, K. H.; Murphy, M.; Galloway, J. G.; Haddox, H. K.; Matsen, F. A.; Andersen, K. G.; King, N. P.; Bloom, J. D.

10.1101/2024.02.05.579020 — microbiology — Posted on 2024-02-06

3810 Genotypic and phenotypic characterization of Enterococcus faecalis isolates from periprosthetic joint infections

Willett, J.; Haeberle, A. L.; Greenwood-Quaintance, K. E.; Zar, S.; Johnson, S.; Patel, R.

10.1101/2024.02.06.579140 — microbiology — Posted on 2024-02-06

3811 High-fat and high-carbohydrate diets worsen the mouse brain susceptibility to damage produced by enterohemorrhagic Escherichia coli Shiga toxin 2

Arenas-Mosquera, D.; Cerny, N.; Cangelosi, A.; Geoghegan, P. A.; Malchiodi, E. L.; De Marzi, M.; Pinto, A.; Goldstein, J.

10.1101/2024.02.06.579171 — microbiology — Posted on 2024-02-06

3812 Gene regulation of infection-associated L-tartrate metabolism in Salmonella enterica serovar Typhimurium

Rojas, V. K.; Winter, M. G.; Jimenez Lopez, A.; Tanner, N. W.; Crockett, S. L.; Spiga, L.; Hendrixson, D. R.; Winter, S. E.

10.1101/2024.02.05.578992 — microbiology — Posted on 2024-02-06

3813 Corticospinal excitability at rest outside of a task does not differ from task intertrial intervals in healthy adults

Bakken, K.; Horton, C.; Fisher, M.; Wadsley, C. G.; Greenhouse, I.

10.1101/2024.02.05.578973 — neuroscience — Posted on 2024-02-06

3814 GenerRNA: A generative pre-trained language model for de novo RNA design

Zhao, Y.; Oono, K.; Takizawa, H.; Kotera, M.

10.1101/2024.02.01.578496 — bioinformatics — Posted on 2024-02-06

3815 Point mutation in a virus-like capsid drives symmetry reduction to form tetrahedral cages

Szyszka, T. N.; Andreas, M. P.; Lie, F.; Miller, L. M.; Adamson, L. S. R.; Fatehi, F.; Twarock, R.; Draper, B. E.; Jarrold, M. F.; Giessen, T. W.; Lau, Y. H.

10.1101/2024.02.05.579038 — biochemistry — Posted on 2024-02-06

3816 Combining Unity with machine vision to create low latency, flexible, and simple virtual realities

Ogawa, Y.; Aoukar, R.; Leibbrandt, R.; Manger, J.; Bagheri, Z.; Turnbull, L.; Johnston, C.; Kaushik, P.; Hemmi, J. M.; Nordstrom, K.

10.1101/2024.02.05.579029 — animal behavior and cognition — Posted on 2024-02-06

3817 Natural selection exerted by historical coronavirus epidemic(s): comparative genetic analysis in China Kadoorie Biobank and UK Biobank

Morris, S. C.; Lin, K.; Millwood, I. Y.; Yu, C.; Lv, J.; Pei, P.; Li, L.; Sun, D.; Davey Smith, G.; Chen, Z.; Walters, R. G.

10.1101/2024.02.06.579075 — genomics — Posted on 2024-02-06

3818 De novo mutations mediate phenotypic switching in an opportunistic human lung pathogen

Poret, A. J.; Schaefers, M. M.; Merakou, C.; Mansour, K. E.; Lagoudas, G. K.; Cross, A. R.; Goldberg, J. B.; Kishony, R.; Uluer, A. Z.; McAdam, A. J.; Blainey, P. C.; Vargas, S. O.; Lieberman, T. D.; Priebe, G. P.

10.1101/2024.02.06.579193 — microbiology — Posted on 2024-02-06

3819 Gut microbial-mediated polyphenol metabolism is restrained by parasitic whipworm infection and associated with altered immune function in mice

Andersen-Civil, A. I. S.; Arora, P.; Zhu, L.; Myhill, L. J.; Budeyri Gokgoz, N.; Castro-Mejia, J. L.; Leppa, M.; Hansen, L. H.; Lessard-Lord, J.; Salminen, J.-P.; Thamsborg, S. M.; Nielsen, D. S.; Desjardins, Y.; Williams, A. R.

10.1101/2024.02.06.579078 — microbiology — Posted on 2024-02-06

3820 Lytic bacteriophages interact with respiratory epithelial cells and induce the secretion of antiviral and proinflammatory cytokines

Zamora, P. F.; Reidy, T. G.; Armbruster, C. R.; Sun, M.; Van Tyne, D.; Turner, P. E.; Koff, J. L.; Bomberger, J. M.

10.1101/2024.02.06.579115 — microbiology — Posted on 2024-02-06

3821 Genetic dissection of the tissue-specific roles of type III effectors and phytotoxins in the pathogenicity of Pseudomonas syringae pv. syringae to cherry

Vadillo Dieguez, A.; Zeng, Z.; Mansfield, J. W.; Grinberg, N. F.; Lynn, S. C.; Gregg, A.; Connell, J.; Harrison, R. J.; Jackson, R. W.; Hulin, M. T.

10.1101/2024.02.06.578989 — microbiology — Posted on 2024-02-06

3822 (p)ppGpp-mediated GTP homeostasis ensures the survival and antibiotic tolerance of Staphylococcus aureus during starvation by preserving the proton motive force

Salzer, A.; Ingrassia, S.; Sauer, L.; Rapp, J.; Dobritz, R.; Muller, J.; Link, H.; Wolz, C.

10.1101/2024.02.06.579068 — microbiology — Posted on 2024-02-06

3823 Evolution of a Plasmid Regulatory Circuit Ameliorates Plasmid Fitness Cost

Elg, C. A.; Mack, E.; Rolfsmeier, M.; McLean, T. C.; Kosterlitz, O.; Soderling, E.; Narum, S.; Rowley, P. A.; Thomas, C. M.; Top, E. M.

10.1101/2024.02.05.579024 — microbiology — Posted on 2024-02-06

3824 Comparative Metagenomics Provide Mechanistic Insights into the Biodegradation of the Non-hydrolysable Plastic Polyvinyl Chloride in Gut Microbiota of Insect Larvae

Peng, H.; Zhang, Z.; Kang, X.; Zhang, y.; Zhang, H.; Wang, Y.; Yang, D.; Zhang, J.; Wang, Y.; Zhu, Y.-G.; Ju, F.

10.1101/2024.02.06.579071 — microbiology — Posted on 2024-02-06

3825 Mapping glycoprotein structure reveals defining events in the evolution of the Flaviviridae

Mifsud, J. C. O.; Lytras, S.; Oliver, M. R.; Toon, K.; Costa, V. A.; Holmes, E. C.; Grove, J.

10.1101/2024.02.06.579159 — microbiology — Posted on 2024-02-06

3826 A retinotopic reference frame for space throughout human visual cortex

Szinte, M.; de Hollander, G.; Aqil, M.; Verissimo, I.; Dumoulin, S.; Knapen, T.

10.1101/2024.02.05.578862 — neuroscience — Posted on 2024-02-06

3827 Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype

Subramanian, D.; Eisenberg, C.; Huang, A.; Baek, J.; Naveed, H.; Komatireddy, S.; Shiflett, M. W.; Tran, T. S.; Santhakumar, V.

10.1101/2024.02.05.578976 — neuroscience — Posted on 2024-02-06

3828 Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories

Sorg, B. A.; Wingert, J. C.; Ramos, J. D.; Reynolds, S. X.; Gonzalez, A. E.; Rose, R. M.; Hegarty, D. M.; Aicher, S. A.; Bailey, L. G.; Brown, T. E.; Abbas, A. I.

10.1101/2024.02.05.577568 — neuroscience — Posted on 2024-02-06

3829 Circadian rhythmicity and photobiological mechanisms of light sensitivity and discomfort glare in humans

Daguet, I.; Raverot, V.; Gronfier, C.

10.1101/2024.02.05.578180 — neuroscience — Posted on 2024-02-06

3830 Kappa Opioid Receptors Negatively Regulate Real Time Spontaneous Dopamine Signals by Reducing Release and Increasing Uptake

Wallace, C. W.; Holleran, K. M.; Slinkard, C. Y.; Centanni, S. W.; Jones, S. R.

10.1101/2024.02.05.578840 — neuroscience — Posted on 2024-02-06

3831 Explicit and implicit locomotor learning in individuals with chronic hemiparetic stroke

Wood, J. M.; Thompson, E. M.; Wright, H.; Festa, L.; Morton, S. M.; Reisman, D. S.; Kim, H. E.

10.1101/2024.02.04.578807 — neuroscience — Posted on 2024-02-06

3832 Inferring the Joint Distribution of Structural and Functional Connectivity in the Human Brain using UNIT-DDPM

Canamedi, V.

10.1101/2024.02.03.578750 — neuroscience — Posted on 2024-02-06

3833 Wavelet Phase Coherence of Ictal Scalp EEG-Extracted Muscle Activity (SMA) as a Biomarker for Sudden Unexpected Death in Epilepsy (SUDEP)

Gravitis, A. C.; Sivendiran, K.; Tufa, U.; Zukotynski, K.; Chinvarun, Y.; Devinsky, O.; Wennberg, R.; Carlen, P. L.; Bardakjian, B. L.

10.1101/2024.02.04.578837 — neuroscience — Posted on 2024-02-06

3834 Beyond over- or under-sampling: autistic children's inflexibility in sampling costly information

Lu, H.; Zhang, H.; Yi, L.

10.1101/2024.02.04.578786 — neuroscience — Posted on 2024-02-06

3835 Neural ensembles that encode affective mechanical and heat pain in mouse spinal cord

Zhang, M.-D.; Kupari, J.; Su, J.; Hu, Y.; Magnusson, K. A.; Calvo-Enrique, L.; Usoskin, D.; Albisetti, G. A.; Leavitt, A. D.; Zeilhofer, H. U.; Hokfelt, T.; Lagerstrom, M. C.; Ernfors, P.

10.1101/2024.02.05.578816 — neuroscience — Posted on 2024-02-06

3836 The Effect on Speech-in-Noise Perception of Real Faces and Synthetic Faces Generated with either Deep Neural Networks or the Facial Action Coding System

Yu, Y.; Lado, A.; Zhang, Y.; Magnotti, J. F.; Beauchamp, M. S.

10.1101/2024.02.05.578468 — neuroscience — Posted on 2024-02-06

3837 Brain-controlled augmented hearing for spatially moving conversations in multi-talker environments

Choudhari, V.; Han, C.; Bickel, S.; Mehta, A. D.; Schevon, C.; McKhann, G. M.; Mesgarani, N.

10.1101/2024.02.05.579018 — neuroscience — Posted on 2024-02-06

3838 Decoding and reconstruction of surface materials from EEG

Orima, T.; Wakita, S.; Motoyoshi, I.

10.1101/2024.02.05.578885 — neuroscience — Posted on 2024-02-06

3839 Proactive selective attention across competition contexts

Aguado-Lopez, B.; Palenciano, A. F.; Penalver, J. M. G.; Diaz-Gutierrez, P.; Lopez-Garcia, D.; Avancini, C.; Ciria, L. F.; Ruz, M.

10.1101/2024.02.06.579112 — neuroscience — Posted on 2024-02-06

3840 Feasibility of decoding covert speech in ECoG with aTransformer trained on overt speech

Komeiji, S.; Mitsuhashi, T.; Iimura, Y.; Suzuki, H.; Sugano, H.; Shinoda, K.; Tanaka, T.

10.1101/2024.02.05.578911 — neuroscience — Posted on 2024-02-06

3841 A new approach for estimating effective connectivity from activity in neural networks

Laasch, N.; Braun, W.; Knoff, L.; Bielecki, J.; Hilgetag, C. C.

10.1101/2024.02.05.578871 — neuroscience — Posted on 2024-02-06

3842 Brain Age Analysis and Dementia Classification using Convolutional Neural Networks trained on Diffusion MRI: Tests in Indian and North American Cohorts

Chattopadhyay, T.; Joshy, N. A.; Ozarkar, S. S.; Buwa, K. S.; Feng, Y.; Laltoo, E.; Thomopoulos, S. I.; Villalon-Reina, J. E.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Thompson, P. M.

10.1101/2024.02.04.578829 — neuroscience — Posted on 2024-02-06

3843 Early altered directionality of resting brain network state transitions in the TgF344-AD rat model of Alzheimer's disease

De Waegenaere, S.; van den Berg, M.; Keliris, G. A.; Adhikari, M. H.; Verhoye, M.

10.1101/2024.02.05.578351 — neuroscience — Posted on 2024-02-06

3844 Human Motor Cortex Encodes Complex Handwriting Through a Sequence of Primitive Neural States

Qi, Y.; Zhu, X.; Xiong, X.; Yang, X.; Ding, N.; Wu, H.; Xu, K.; Zhu, J.; Zhang, J.; Wang, Y.

10.1101/2024.02.05.578548 — neuroscience — Posted on 2024-02-06

3845 Deep Normative Tractometry for Identifying Joint White Matter Macro- and Micro-structural Abnormalities in Alzheimer's Disease

Feng, Y.; Chandio, B. Q.; Villalon-Reina, J. E.; Benavidez, S.; Chattopadhyay, T.; Chehrzadeh, S.; Laltoo, E.; Thomopoulos, S. I.; Joshi, H.; Venkatasubramanian, G.; John, J. P.; Jahanshad, N.; Thompson, P. M.

10.1101/2024.02.05.578943 — neuroscience — Posted on 2024-02-06

3846 UniFed: A unified deep learning framework for segmentation of partially labelled, distributed neuroimaging data

Dinsdale, N. K.; Jenkinson, M.; Namburete, A. I.

10.1101/2024.02.05.578912 — neuroscience — Posted on 2024-02-06

3847 MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures

Sit, T. P.; Feord, R. C.; Dunn, A. W.; Chabros, J.; Oluigbo, D.; Smith, H. H.; Burn, L.; Chang, E.; Boschi, A.; Yuan, Y.; Gibbons, G. M.; Khayat-Khoei, M.; De Angelis, F.; Hemberg, E.; Hemberg, M.; Lancaster, M. A.; Lakatos, A.; Eglen, S. J.; Paulsen, O.; Mierau, S. B.

10.1101/2024.02.05.578738 — neuroscience — Posted on 2024-02-06

3848 Crebinostat Facilitates Memory Formation

Dama, D.; Sharma, S.

10.1101/2024.02.05.578875 — neuroscience — Posted on 2024-02-06

3849 Multimodal brain age prediction using machine learning: combining structural MRI and 5-HT2AR PET derived features

Dörfel, R.; Arenas-Gomez, J. M.; Svarer, C.; Ganz, M.; Knudsen, G. M.; Svensson, J.; Plaven-Sigray, P.

10.1101/2024.02.05.578968 — neuroscience — Posted on 2024-02-06

3850 Wearable Neural Interfaces: Real-Time Identification of Motor Neuron Discharges in Dynamic Motor Tasks

Mendez Guerra, I.; Barsakcioglu, D. Y.; Farina, D.

10.1101/2024.02.05.578874 — neuroscience — Posted on 2024-02-06

3851 WildPose: A Long-Range 3D wildlife motion capture system

Muramatsu, N.; Shin, S.; Deng, Q.; Markham, A.; Patel, A.

10.1101/2024.02.05.578861 — animal behavior and cognition — Posted on 2024-02-06

3852 The Guinea Pig: A New Model for Human Preimplantation Development

Canizo, J. R.; Zhao, C.; Petropoulos, S.

10.1101/2024.02.05.578945 — developmental biology — Posted on 2024-02-06

3853 Osiris gene family defines the cuticle nano-patterns of Drosophila

Sun, Z.; Inagaki, S.; Miyoshi, K.; Saito, K.; Hayashi, S.

10.1101/2024.02.06.579014 — developmental biology — Posted on 2024-02-06

3854 Brain and grammar: revealing electrophysiological basic structures with competing statistical models

Cometa, A.; Battaglini, C.; Artoni, F.; Greco, M.; Frank, R.; Repetto, C.; Bottoni, F.; Cappa, S. F.; Micera, S.; Ricciardi, E.; Moro, A.

10.1101/2024.02.06.579088 — neuroscience — Posted on 2024-02-06

3855 A next-generation, histological atlas of the human brain and its application to automated brain MRI segmentation

Casamitjana, A.; Mancini, M.; Robinson, E.; Peter, L.; Annunziata, R.; Althonayan, J.; Crampsie, S.; Blackburn, E.; Billot, B.; Atzeni, A.; Puonti, O.; Balbastre, Y.; Schmidt, P.; Hughes, J.; Augustinack, J.; Edlow, B. L.; Zollei, L.; Thomas, D.; Kliemann, D.; Bocchetta, M.; Strand, C.; Holton, J.; Jaunmuktane, Z.; Iglesias, J. E.

10.1101/2024.02.05.579016 — neuroscience — Posted on 2024-02-06

3856 The epigenetic landscape of oligodendrocyte progenitors changes with time

Casaccia, P.; Dansu, D.; Sauma, S.; Huang, D.; Li, M.; Moyon, S.

10.1101/2024.02.06.579145 — neuroscience — Posted on 2024-02-06

3857 Drosophila HCN mediates gustatory homeostasis by preserving sensillar transepithelial potential in sweet environments

Lee, M.; Park, S. H.; Joo, K. M.; Kwon, J. Y.; Lee, K.-H.; Kang, K.

10.1101/2024.02.06.579099 — neuroscience — Posted on 2024-02-06

3858 Distinct Effects of Aducanumab and Lecanemab on Intraneuronal Endogenous Aβ42 and Phosphorylated Tau in Alzheimer's Disease Treatment

Liu, M.-J.; Long, Z.; Li, F.; Shi, X.; Shen, Y.-F.; Liu, M.-L.

10.1101/2024.02.06.579113 — neuroscience — Posted on 2024-02-06

3859 Sleep need driven oscillation of glutamatergic synaptic phenotype

Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.

10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-02-06

3860 A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease

Haage, V. C.; Tuddenham, J. F.; Comandante-Lou, N.; Bautista, A.; Monzel, A.; Chiu, R.; Fujita, M.; Garcia, F. G.; Bhattarai, P.; Patel, R.; Buonfiglioli, A.; Idiarte, J.; Herman, M.; Rinderspacher, A.; Mela, A.; Zhao, W.; Argenziano, M. G.; Furnari, J. L.; Banu, M. A.; Landry, D. W.; Bruce, J. N.; Canoll, P.; Zhang, Y.; Nuriel, T.; Kizil, C.; Sproul, A. A.; de Witte, L. D.; Sims, P. A.; Menon, V.; Picard, M.; De Jager, P. L.

10.1101/2024.02.06.579103 — neuroscience — Posted on 2024-02-06

3861 Cortico-spinal Mechanisms of Periphery Neuromodulation induced Analgesia

Wei, Z.; Duan, Y.; Zhu, Y.; Lin, X.; Zhang, M.; Brooks, J. C. W.; Liu, Y.; Hu, L.; Kong, Y.

10.1101/2024.02.06.579059 — neuroscience — Posted on 2024-02-06

3862 Identifying Interpretable Latent Factors with Sparse Component Analysis

Zimnik, A. J.; Ames, K. C.; An, X.; Driscoll, L.; Lara, A. H.; Russo, A. A.; Susoy, V.; Cunningham, J. P.; Paninski, L.; Churchland, M. M.; Glaser, J. I.

10.1101/2024.02.05.578988 — neuroscience — Posted on 2024-02-06

3863 Local muscle pressure stimulates the principal receptors for proprioception

Torell, F.; Dimitriou, M.

10.1101/2024.02.06.579058 — neuroscience — Posted on 2024-02-06

3864 Cholinergic modulation of interhemispheric inhibition in the mouse motor cortex

Handa, T.; Zhang, Q.; Aizawa, H.

10.1101/2024.02.05.579044 — neuroscience — Posted on 2024-02-06

3865 Visually Induced Involuntary Movements

Martin, A.; Bakshi, A.; Ventura, J.; Lackner, J. R.

10.1101/2024.02.06.578999 — neuroscience — Posted on 2024-02-06

3866 Predictive processing in biological motion perception: Evidence from human behavior

Elmas, H. O.; Er, S.; Boyaci, H.; Urgen, B. A.; Rezaki, A. D.; Izgi, A.; Urgen, B. M.

10.1101/2024.02.03.578729 — neuroscience — Posted on 2024-02-06

3867 Evaluating Cochlear Implant Stimulation Strategies Through Wide-field Calcium Imaging of the Auditory Cortex

Castellaro, B.; Yip, K. W.; Peng, F.; Zeeshan, M.; Fang, S.; Nelken, I.; Schnupp, J. W. H.

10.1101/2024.02.05.577161 — neuroscience — Posted on 2024-02-06

3868 Non-cell autonomous OTX2 in the piriform cortex regulates parvalbumin cell maturation states and olfactory-driven behavior

Gibel-Russo, R.; Di Nardo, A. A.

10.1101/2024.02.04.578782 — neuroscience — Posted on 2024-02-06

3869 Fine-scale tracking reveals visual field use for predator detection and escape in collective foraging of pigeon flocks

Delacoux, M.; Kano, F.

10.1101/2024.02.05.578919 — animal behavior and cognition — Posted on 2024-02-06

3870 hoxb genes determine the timing of cell ingression by regulating cell surface fluctuations during zebrafish gastrulation

Moriyama, Y.; Mitsui, T.; Heisenberg, C.-P.

10.1101/2024.02.06.579056 — developmental biology — Posted on 2024-02-06

3871 BMI1 regulates human erythroid self-renewal through both gene repression and gene activation

McGrath, K. E.; Koniski, A. D.; Murphy, K.; Getman, M.; An, H. H.; Schulz, V. P.; Kim, A.; Zhang, B.; Schofield, T. L.; Papoin, J.; Blanc, L.; Kingsley, P. D.; Westhoff, C. M.; Gallagher, P. G.; Chou, S. T.; Steiner, L. A.; Palis, J.

10.1101/2024.02.02.578704 — cell biology — Posted on 2024-02-06

3872 Senolytic treatment depletes microglia and decreases severity of experimental autoimmune encephalomyelitis.

Drake, S. S.; Zaman, A.; Gianfelice, C.; Hua, E. M.- L.; Heale, K.; Afanasiev, E.; STRATTON, J. A.; Fournier, A.

10.1101/2024.02.05.579017 — neuroscience — Posted on 2024-02-06

3873 Model-Agnostic Neural Mean Field With The Refractory SoftPlus Transfer Function

Spaeth, A.; Haussler, D.; Teodorescu, M.

10.1101/2024.02.05.579047 — neuroscience — Posted on 2024-02-06

3874 Restraining Wnt activation and intestinal tumorigenesis by a Rab35 dependent GTPase relay

Redhai, S.; Eang, T.; Boonekamp, K. E.; Rueter, S.; Klemens, T. C.; Leible, S.; Bahuguna, S.; Port, F.; Pavlovic, B.; Holzem, M.; Doll, R.; Rindtorff, N.; Valentini, E.; Schmitt, B.; Richter, K.; Engel, U.; Huber, W.; Boutros, M.

10.1101/2024.02.05.578891 — cancer biology — Posted on 2024-02-06

3875 The mechanism of mammalian proton-coupled peptide transporters

Lichtinger, S. M.; Parker, J. L.; Newstead, S.; Biggin, P.

10.1101/2024.02.04.578827 — biophysics — Posted on 2024-02-06

3876 Cellular (de)coordination in gliding motility and plectoneme formation

Rosko, J.; Cremin, K.; Locatelli, E.; Coates, M.; Duxbury, S. J. N.; Soyer, O. S.; Croft, K.; Randall, K.; Valeriani, C.; Polin, M.

10.1101/2024.02.06.579126 — biophysics — Posted on 2024-02-06

3877 QOT: Efficient Computation of Sample Level Distance Matrix from Single-Cell Omics Data through Quantized Optimal Transport

Wang, Z.; Zhan, Q.; Yang, S.; Mu, S.; Chen, J.; Garai, S.; Orzechowski, P.; Wagenaar, J.; Shen, L.

10.1101/2024.02.06.578032 — bioinformatics — Posted on 2024-02-06

3878 Allele age estimators designed for whole genome datasets show only a modest decrease in accuracy when applied to whole exome datasets.

Pivirotto, A.; Peles, N.; Hey, J.

10.1101/2024.02.01.578465 — genomics — Posted on 2024-02-06

3879 Trophic niche partitioning in symbiotic marine invertebrates

Guibert, I.; Conti-Jerpe, I.; Pons, L.; Tayaban, K.; Sayco, S. L.; Cabaitan, P.; Conaco, C.; Baker, D. M.

10.1101/2024.02.05.578332 — ecology — Posted on 2024-02-06

3880 Individual performance niches may buffer population responses to climate change in estuarine fishes

Bellotto, C.; Fowler, A.; Booth, D.

10.1101/2024.02.01.578478 — ecology — Posted on 2024-02-06

3881 Fluctuating salinity during development impacts fish productivity

Chung, M.-H.; Noble, D. W. A.; Fox, R. J.; Harrison, L. M.; Jennions, M. D.

10.1101/2024.02.01.578515 — ecology — Posted on 2024-02-06

3882 A single-cell 3D spatiotemporal multi-omics atlas from Drosophila embryogenesis to metamorphosis

Wang, M.; Hu, Q.; Tu, Z.; Kong, L.; Yao, J.; Xiang, R.; Chen, Z.; Zhao, Y.; Zhou, Y.; Yu, T.; Wang, Y.; Jia, Z.; Ouyang, K.; Wang, X.; Bai, Y.; Lian, M.; Yang, Z.; Yang, T.; Chen, J.; Huang, Y.; Yin, N.; Mo, W.; Liang, W.; Liu, C.; Lin, X.; Liu, C.; Gu, Y.; Chen, W.; Liu, L.; Xu, X.; Hu, Y.

10.1101/2024.02.06.577903 — developmental biology — Posted on 2024-02-06

3883 Ca2+-driven cytoplasmic backflow secures spindle position in fertilized mouse eggs

Totsuka, T.; Ohsugi, M.

10.1101/2024.02.05.578955 — cell biology — Posted on 2024-02-06

3884 Genomic context-dependent histone H3K36 methylation by three Drosophila methyltransferases and implications for dedicated chromatin readers

Jayakrishnan, M.; Havlova, M.; Veverka, V.; Regnard, C.; Becker, P. B.

10.1101/2024.02.06.577191 — molecular biology — Posted on 2024-02-06

3885 Building Blocks of Understanding: Constructing a Reverse Genetics Platform for studying determinants of SARS-CoV-2 replication.

Olguin-Nava, M.; Bohn, P.; Hennig, T.; Boertlein, C.; Gribling-Burrer, A.-S.; Schmidt, N.; Caliskan, N.; Doelken, L.; Munschauer, M.; Smyth, R. P.

10.1101/2024.02.05.578560 — microbiology — Posted on 2024-02-06

3886 Effects of excess phosphate on a coastal plankton community

Spilling, K.; Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Labrenz, M.; Grossart, H.-P.; Piwosz, K.

10.1101/2024.02.05.576994 — microbiology — Posted on 2024-02-06

3887 Second Boost of Omicron SARS-CoV-2 S1 Subunit Vaccine Induced Broad Humoral Immune Responses in Elderly Mice

Kim, E.; Khan, M. S.; Ferrari, A.; Huang, S.; Kenniston, T. W.; Cassaniti, I.; Baldanti, F.; Gambotto, A.

10.1101/2024.02.05.578925 — immunology — Posted on 2024-02-06

3888 Identification and Structural Characterization of a mutant KRAS-G12V specific TCR restricted by HLA-A3

Sim, M. J. W.; Hanada, K.-i.; Stotz, Z. S.; Yu, Z.; Lu, J.; Brennan, P.; Quastel, M.; Gillespie, G.; Long, E. O.; Yang, J. C.; Sun, P. D.

10.1101/2024.02.01.578367 — immunology — Posted on 2024-02-06

3889 The Origin and Evolution of Orphan Genes: A Case Study in Tea Plant Family

Cheng, L.; Hao, Y.; Han, Q.; Qiao, Z.; Li, M.; Liu, D.; Yin, H.; Li, T.; Long, W.; Luo, S.; Gao, Y.; Zhang, Z.; Yu, H.; Sun, X.; ZHAO, Y.

10.1101/2024.02.01.578514 — bioinformatics — Posted on 2024-02-06

3890 Large-scale multi-omics analyses identified root-microbiome associations underlying plant nitrogen nutrition

Li, N.; Li, G.; Wang, D.; Ma, L.; Huang, X.; Bai, Z.; Wang, Y.; Luo, M.; Luo, Y.; Zhu, Y.; Cao, X.; Feng, Q.; Xu, Y.; Mu, J.; An, R.; Yang, C.; Chen, H.; Li, X.; Dong, Y.; Zhao, J.; Jiang, L.; Jiang, Y.; Reif, J. C.; Hochholdinger, F.; Chen, X.; Wang, D.; Zhang, Y.; Bai, Y.; Yu, P.

10.1101/2024.02.05.578621 — plant biology — Posted on 2024-02-06

3891 Hibiscus bullseyes reveal mechanisms controlling petal pattern proportions that influence plant-pollinator interactions

Riglet, L.; Zardilis, A.; Fairnie, A. L.; Yeo, M. T. S.; Jonsson, H.; Moyroud, E.

10.1101/2024.02.05.579006 — plant biology — Posted on 2024-02-06

3892 A comprehensive examination of Chelicerate genomes reveals no evidence for a whole genome duplication among spiders and scorpions

Thomas, G. W. C.; McKibben, M. T. W.; Hahn, M. W.; Barker, M. S.

10.1101/2024.02.05.578966 — evolutionary biology — Posted on 2024-02-06

3893 Insights into ontogenetic scaling and morphological variation in sharks from near-term brown smooth-hound (Mustelus henlei) embryos

Gayford, J. H.; Sternes, P. C.; Seamone, S. G.; Godfrey, H.; Whitehead, D. A.

10.1101/2024.02.05.578906 — evolutionary biology — Posted on 2024-02-06

3894 Quantifying internal conflicts and their threats to organismal form and fitness

Schenkel, M. A.; Patten, M. M.; Agren, J. A.

10.1101/2024.02.05.578856 — evolutionary biology — Posted on 2024-02-06

3895 Variability in drought gene expression datasets highlight the need for community standardization

VanBuren, R.; Nguyen, A.; Marks, R. A.; Mercado, C.; Pardo, A.; Pardo, J.; Schuster, J.; St. Aubin, B.; Wilson, M. L.; Rhee, S. Y.

10.1101/2024.02.04.578814 — plant biology — Posted on 2024-02-06

3896 Translational activation by a synthetic PPR protein elucidates control of psbA translation in Arabidopsis chloroplasts

Rojas, M.; Chotewutmontri, P.; Barkan, A.

10.1101/2024.02.05.578914 — plant biology — Posted on 2024-02-06

3897 WITHDRAWN: Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour

Bosworth, M. L.; Isles, A. R.; Wilkinson, L. S.; Humby, T.

10.1101/2024.01.31.578257 — animal behavior and cognition — Posted on 2024-02-06

3898 WITHDRAWN: Oncogenic KRASG12D extrinsically induces an immunosuppressive microenvironment in lung adenocarcinoma

Lasse-Opsahl, E.; Baliira, R.; Barravecchia, I.; McLintock, E.; Lee, J. M.; Ferris, S. F.; Espinoza, C. E.; Hinshaw, R.; Cavanaugh, S.; Robotti, M.; Brown, K.; Donahue, K.; Abdelmalak, K. Y.; Galban, C. J.; Frankel, T. L.; Zhang, Y.; Pasca di Magliano, M.; Galban, S.

10.1101/2024.01.16.568090 — cancer biology — Posted on 2024-02-06

3899 Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1

Henry, S.; Lewis, S. M.; Cyrill, S. L.; Callaway, M. K.; Chatterjee, D.; Somasundara, A. V. H.; Jones, G.; He, X. Y.; Caligiuri, G.; Ciccone, M. F.; Diaz, I. A.; Biswas, A.; Hernandez, E.; Ha, T.; Wilkinson, J. E.; EGEBLAD, M.; Tuveson, D.; Dos Santos, C. O.

10.1101/2024.02.05.578977 — developmental biology — Posted on 2024-02-06

3900 The Optimization of High-Protein Duckweed Cultivation in Eutrophicated Water with Mutualistic Bacteria

Akkarajeerawat, S.; Chauvanasmith, T.; Keatsirisart, C.

10.1101/2024.02.05.578878 — plant biology — Posted on 2024-02-06

3901 Convolutions are competitive with transformers for protein sequence pretraining

Yang, K. K.; Fusi, N. K.; Lu, A. X.

10.1101/2022.05.19.492714 — bioengineering — Posted on 2024-02-06

3902 The Brain Tells a Story: Unveiling Distinct Representations of Semantic Content in Speech, Objects, and Stories in the Human Brain with Large Language Models

Nakagi, Y.; Matsuyama, T.; Koide-Majima, N.; Yamaguchi, H.; Kubo, R.; Nishimoto, S.; Takagi, Y.

10.1101/2024.02.06.579077 — neuroscience — Posted on 2024-02-06

3903 Depression Attenuates Caudate and Dorsolateral Prefrontal Cortex Alpha and Beta Power Response to Reward

Qian, H.; Johnson, G. W.; Hughes, N. C.; Paulo, D. L.; Zhao, Z.; Subramanian, D.; Dhima, K.; Bick, S. K.

10.1101/2024.02.05.578848 — neuroscience — Posted on 2024-02-06

3904 Genome-wide CRISPR screen identifies AC9 as a key regulator of ER calcium homeostasis involved in neuronal differentiation.

Wang, L.; Li, J.; Wang, Y.; Zhong, Z.; Wang, Y.; Huang, R.; Zhang, B.; Liu, P.; Ye, E.; Cao, R.; Ali, S.; Ke, Y.; Yang, J.; Yokoyama, T.; Liu, J.; Zhang, X.; Sakamoto, M.; Sun, L.; Zhou, Y.; Wang, Y.

10.1101/2024.02.05.578803 — cell biology — Posted on 2024-02-06

3905 Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

Warfvinge, R.; Geironson Ulfsson, L.; Dhapola, P.; Safi, F.; Sommarin, M. N. E.; Soneji, S.; Hjorth-Hansen, H.; Mustjoki, S.; Richter, J.; Krishna Thakur, R.; Karlsson, G.

10.1101/2023.08.16.553504 — cancer biology — Posted on 2024-02-06

3906 Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organism

Pimmett, V. L.; Douaihy, M.; Maillard, L.; Trullo, A.; Radulescu, O.; Lagha, M.

10.1101/2024.02.05.577724 — molecular biology — Posted on 2024-02-06

3907 The (Limited?) Utility of Brain Age as a Biomarker for Capturing Fluid Cognition in Older Individuals

Tetereva, A.; Pat, N.

10.1101/2022.12.31.522374 — neuroscience — Posted on 2024-02-06

3908 A binding site for phosphoinositides described by multiscale simulations explains their modulation of voltage gated sodium channels

Lin, Y.; Tao, E.; Champion, J. P.; Corry, B.

10.1101/2023.07.16.547149 — biophysics — Posted on 2024-02-06

3909 ICoN: Integration using Co-attention across Biological Networks

Tasnina, N.; Murali, T. M.

10.1101/2024.02.05.577786 — systems biology — Posted on 2024-02-06

3910 Metagenomic estimation of dietary intake from human stool

Diener, C.; Gibbons, S. M.

10.1101/2024.02.02.578701 — bioinformatics — Posted on 2024-02-06

3911 Decoding the Impact of Neighboring Amino Acid on MS Intensity Output through Deep Learning

Abdul-Khalek, N.; Wimmer, R.; Overgaard, M. T.; Gregersen Echers, S.

10.1101/2024.02.02.578588 — bioinformatics — Posted on 2024-02-06

3912 Mountable miniature microphones to identify and assign mouse ultrasonic vocalizations

Waidmann, E. N.; Yang, V. H.; Doyle, W. C.; Jarvis, E. D.

10.1101/2024.02.05.579003 — animal behavior and cognition — Posted on 2024-02-06

3913 Quantifying the fitness effects of resistance alleles with and without anthelmintic selection pressure using Caenorhabditis elegans

Shaver, A. O.; Miller, I. R.; Schaye, E. S.; Moya, N. D.; Collins, J. B.; Wit, J.; Blanco, A. H.; Shao, F. M.; Andersen, E. J.; Khan, S. A.; Paredes, G.; Andersen, E. C.

10.1101/2024.02.01.578300 — genetics — Posted on 2024-02-06

3914 A covariant model of molecular and diversification patterns through time and the history of large clades

Budd, G. E.; Mann, R. P.

10.1101/2024.02.01.578373 — evolutionary biology — Posted on 2024-02-06

3915 Microbes as manipulators of developmental life-history

Kustra, M. C.; Carrier, T. J.

10.1101/2024.02.02.578589 — evolutionary biology — Posted on 2024-02-06

3916 Plastid phylogenomics reveals evolutionary relationships in the mycoheterotrophic orchid genus Dipodium and provides insights into plastid gene degeneration

Goedderz, S.; Clements, M. A.; Bent, S. J.; Nicholls, J. A.; Patel, V. S.; Crayn, D. M.; Schlueter, P. M.; Nargar, K.

10.1101/2024.02.05.578113 — evolutionary biology — Posted on 2024-02-06

3917 Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae

Large, C. R. L.; Khanal, R.; Hillier, L. W.; Huynh, C.; Kubo, C.; Kim, J.; Waterston, R.; Murray, J. I.

10.1101/2024.02.03.578695 — evolutionary biology — Posted on 2024-02-06

3918 Increased evolutionary rate in the Z-chromosome of Morpho butterflies and implications for speciation.

Lopez Villavicencio, M.; Ledamoisel, J.; Lopez-Roques, C.; Debat, V.; Llaurens, V.

10.1101/2024.02.02.578590 — evolutionary biology — Posted on 2024-02-06

3919 Does method of field preparation affect survival and growth of juvenile Chinook salmon in agricultural floodplains?

Tallman, R.; Wampler, A.; Singer, G.; Jeffres, C.; Cocherell, D.; Colby, J.; Fangue, N.; Lusardi, R.; Rypel, A.

10.1101/2024.02.02.578246 — ecology — Posted on 2024-02-06

3920 Wasted efforts impair random search efficiency and reduce choosiness in mate-pairing termites

Mizumoto, N.; Nagaya, N.; Fujisawa, R.

10.1101/2024.02.01.578198 — ecology — Posted on 2024-02-06

3921 Featural and spatial interference with functionally active and passive items in working memory

Wilhelm, S.; Akyurek, E.; Weng, Y.; Borst, J. P.; Havekes, R.

10.1101/2024.02.05.578913 — neuroscience — Posted on 2024-02-06

3922 The dimensionality of neural coding for cognitive control is gradually transformed within the lateral prefrontal cortex

Chiou, R.; Duncan, J.; Jefferies, E.; Ralph, M. L.

10.1101/2024.02.05.578918 — neuroscience — Posted on 2024-02-06

3923 Neural signatures of opioid-induced risk-taking behavior in the prelimbic prefrontal cortex

Quave, C. B.; Vasquez, A. M.; Aquino-Miranda, G.; Bora, E. P.; Chidomere, C. L.; Zhang, X. O.; Engelke, D. S.; Do-Monte, F. H.

10.1101/2024.02.05.578828 — neuroscience — Posted on 2024-02-06

3924 Intact Somatosensory Temporal Sensitivity in Adults on the Autism Spectrum: A High-Density Electrophysiological Mapping Study Using the Mismatch Negativity (MMN) Sensory Memory Paradigm.

Isenstein, E. L.; Freedman, E. G.; Molholm, S.; Foxe, J. J.

10.1101/2024.02.05.578908 — neuroscience — Posted on 2024-02-06

3925 Distinct dynamics and intrinsic properties in ventral tegmental area populations mediate reward association and motivation

Elum, J. E.; Szelenyi, E. R.; Juarez, B.; Murry, A. D.; Loginov, G.; Zamorano, C. A.; Gao, P.; Wu, G.; Ng-Evans, S.; Xu, X.; Golden, S. A.; Zweifel, L. S.

10.1101/2024.02.05.578997 — neuroscience — Posted on 2024-02-06

3926 A Functional and Non-Homuncular Representation of the Larynx in the Primary Motor Cortex of Mice, a Vocal Non-Learner

Vargas, C. D. M.; Agravat, R. K.; Waidmann, E. N.; Bochalis, C.; Bermudez, H.; Giannakopoulos, T.; Jarvis, E. D.

10.1101/2024.02.05.579004 — neuroscience — Posted on 2024-02-06

3927 Examining the relationship between psychosocial adversity and inhibitory control: an fMRI study of children growing up in extreme poverty

Surani, Z.; Turesky, T. K.; Sullivan, E.; Shama, T.; Haque, R.; Islam, N.; Kakon, S. H.; Yu, X.; Petri, W. A.; Nelson, C.; Gaab, N.

10.1101/2024.02.05.578942 — neuroscience — Posted on 2024-02-06

3928 The role of prospective contingency in the control of behavior and dopamine signals during associative learning

Qian, L.; Burrell, M.; Hennig, J. A.; Matias, S.; Murthy, V. N.; Gershman, S. J.; Uchida, N.

10.1101/2024.02.05.578961 — neuroscience — Posted on 2024-02-06

3929 Exploiting threonine sidechains as molecular switches to modulate the fluorescence of genetically encoded biosensors

Leong, L. M.; Shin, S. C.; Rhee, J. K.; Kim, H.; Seong, J.; Woo, J.; Han, K.; Storace, D. A.; Baker, B. J.

10.1101/2022.04.25.489330 — neuroscience — Posted on 2024-02-06

3930 tCFS: A new 'CFS tracking' paradigm reveals uniform suppression depth regardless of target complexity or salience

Alais, D.; Coorey, J.; Blake, R.; Davidson, M. J.

10.1101/2023.04.17.537110 — neuroscience — Posted on 2024-02-06

3931 Photoprotective mechanisms in Elysia species hosting Acetabularia chloroplasts shed light on host-donor compatibility in photosynthetic sea slugs

Morelli, L.; Havurinne, V.; Madeira, D.; Martins, P.; Cartaxana, P.; Cruz, S.

10.1101/2024.02.02.578635 — plant biology — Posted on 2024-02-06

3932 Non-destructive, whole-plant phenotyping reveals dynamic changes in water use efficiency, photosynthesis efficiency, and rhizosphere acidification of sorghum accessions under osmotic stress

Ginzburg, D.; Cox, J. A.; Rhee, S. Y.

10.1101/2023.09.26.559576 — plant biology — Posted on 2024-02-06

3933 Single-cell multi-omics reveals insights into differentiation of rare cell types in mucinous colorectal cancer

Ladaika, C. A.; Ghobashi, A. H.; Boulton, W. C.; Miller, S. A.; O'Hagan, H. M.

10.1101/2024.02.01.578409 — cancer biology — Posted on 2024-02-05

3934 High-throughput identification of the spatial origins of Drosophila optic lobe neurons using single-cell mRNA-sequencing

Simon, F.; Holguera, I.; Chen, Y.-C.; Malin, J.; Valentino, P.; Erclik, T.; Desplan, C.

10.1101/2024.02.05.578975 — developmental biology — Posted on 2024-02-05

3935 The Vps13-like protein BLTP2 is pro-survival and regulates phosphatidylethanolamine levels in the plasma membrane to maintain its fluidity and function

Banerjee, S.; Daetwyler, S.; Bai, X.; Michaud, M.; Jouhet, J.; Madhugiri, S.; Johnson, E.; Wang, C.-W.; Fiolka, R.; Toulmay, A.; Prinz, W. A.

10.1101/2024.02.04.578804 — cell biology — Posted on 2024-02-05

3936 Nuclear pores safeguard the integrity of the nuclear envelope

Taniguchi, R.; Orniacki, C.; Kreysing, J. P.; Zila, V.; Zimmerli, C. E.; Boehm, S.; Turonova, B.; Kraeusslich, H.-G.; Doye, V.; Beck, M.

10.1101/2024.02.05.578890 — cell biology — Posted on 2024-02-05

3937 Metatranscriptomic analysis indicates prebiotic effect of Isomalto/malto-polysaccharides on human colonic microbiota in-vitro

Borewicz, K.; Hornung, B. V. H.; Gu, F.; van der Zaal, P. H.; Schols, H. A.; Schaap, P. J.; Smidt, H.

10.1101/2023.12.31.573771 — microbiology — Posted on 2024-02-05

3938 Spatiotemporal profiling defines persistence and resistance dynamics during targeted treatment of melanoma

Rubinstein, J. C.; Domanskyi, S.; Sheridan, T. B.; Sanderson, B.; Park, S.; Kaster, J.; Li, H.; Anczukow, O.; Herlyn, M.; Chuang, J. H.

10.1101/2024.02.02.577085 — cancer biology — Posted on 2024-02-05

3939 STAR+WASP reduces reference bias in the allele-specific mapping of RNA-seq reads

Asiimwe, R.; Dobin, A.

10.1101/2024.01.21.576391 — bioinformatics — Posted on 2024-02-05

3940 Time-Informed Dimensionality Reduction for Longitudinal Microbiome Studies

Shi, P.; Martino, C.; Han, R.; Janssen, S.; Buck, G.; Serrano, M.; Owzar, K.; Knight, R.; Shenhav, L.; Zhang, A. R.

10.1101/2023.07.26.550749 — bioinformatics — Posted on 2024-02-05

3941 Cross-talk between tissues is critical for intergenerational acclimation to environmental change

Suresh, S.; Welch, M. J.; Munday, P. L.; Ravasi, T.; Schunter, C.

10.1101/2023.11.15.567297 — ecology — Posted on 2024-02-05

3942 Time is of the essence: A general framework for uncovering temporal structures of communities

Yin, H.; Rudolf, V.

10.1101/2023.06.30.546877 — ecology — Posted on 2024-02-05

3943 Single-cell and spatial transcriptomics of the avian embryo tailbud

Mok, G. F.; Turner, S.; Smith, E. L.; Mincarelli, L.; Lister, A.; Lipscombe, J.; Uzun, V.; Haerty, W.; Macaulay, I. C.; Munsterberg, A. E.

10.1101/2024.02.05.578917 — developmental biology — Posted on 2024-02-05

3944 A TBX5-dependent compartment boundary patterns the cardiac interventricular septum

Kathiriya, I. S.; Dominguez, M. H.; Rao, K. S.; Muncie-Vasic, J. M.; Devine, W. P.; Hu, K. M.; Hota, S. K.; Garay, B. I.; Quintero, D.; Goyal, P.; Matthews, M. N.; Thomas, R.; Sukonnik, T.; Miguel-Perez, D.; Winchester, S.; Brower, E. F.; Forjaz, A.; Wu, P.-H.; Wirtz, D.; Kiemen, A. L.; Bruneau, B. G.

10.1101/2024.02.05.578995 — developmental biology — Posted on 2024-02-05

3945 Plasmodium NEK1 coordinates MTOC organisation and kinetochore attachment during rapid mitosis in male gamete formation

Zeeshan, M.; Rashpa, R.; Ferguson, D. J.; Mckeown, G.; Nugmanova, R.; Subodhi, A. K.; Beyeler, R.; Pashley, S. L.; Markus, R.; Brady, D.; Roques, M.; Bottrill, A. R.; Fry, A. M.; Pain, A.; vaughan, s.; Holder, A. A.; Tromer, E. C.; Brochet, M.; Tewari, R.

10.1101/2024.02.05.578160 — cell biology — Posted on 2024-02-05

3946 Artificially inserted G-quadruplex DNA secondary structures induce long-distance chromatin activation

Roy, S. S.; Bagri, S.; Sengupta, A.; Then, C. R.; Kumar, R.; Sridharan, S.; Chowdhury, S.

10.1101/2023.11.27.568900 — molecular biology — Posted on 2024-02-05

3947 Spontaneous activity of striatal projection neurons supports maturation of striatal inputs to substantia nigra dopaminergic neurons

Kokinovic, B.; Seja, P.; Donati, A.; Ryazantseva, M.; de Kerchove d'Exaerde, A.; Schiffmann, S. N.; Taira, T.; Molchanova, S. M.

10.1101/2024.01.05.574371 — neuroscience — Posted on 2024-02-05

3948 A Pvr-AP-1-Mmp1 signaling pathway is activated in astrocytes upon traumatic brain injury

Li, T.; Shi, W.; Ho, M. S.; Zhang, Y. Q.

10.1101/2023.03.27.534488 — neuroscience — Posted on 2024-02-05

3949 Species -Shared and -Unique Gyral Peaks on Human and Macaque Brains

Zhang, S.; Zhang, T.; Cao, G.; Zhou, J.; He, Z.; Li, X.; Ren, Y.; Liu, T.; Jiang, X.; Guo, L.; Han, J.; Liu, T.

10.1101/2023.07.26.550760 — neuroscience — Posted on 2024-02-05

3950 Mismatch novelty exploration training impairs VPAC1 receptor mediated modulation of hippocampal synaptic plasticity by endogenous VIP

Aidil-Carvalho, F.; Caulino-Rocha, A.; Ribeiro, J. A.; Cunha-Reis, D.

10.1101/2022.12.21.521348 — neuroscience — Posted on 2024-02-05

3951 Tools and methods for high-throughput single-cell imaging with the mother machine

Thiermann, R.; Sandler, M.; Ahir, G.; Sauls, J. T.; Schroeder, J. W.; Brown, S. D.; Le Treut, G.; Si, F.; Li, D.; Wang, J.; Jun, S.

10.1101/2023.03.27.534286 — systems biology — Posted on 2024-02-05

3952 Meta-Research: understudied genes are lost in a leaky pipeline between genome-wide assays and reporting of results

Richardson, R. A. K.; Tejedor Navarro, H.; Amaral, L. A. N.; Stoeger, T.

10.1101/2023.02.28.530483 — genomics — Posted on 2024-02-05

3953 sdmTMB: an R package for fast, flexible, and user-friendly generalized linear mixed effects models with spatial and spatiotemporal random fields

Anderson, S. C.; Ward, E. J.; English, P. A.; Barnett, L. A. K.; Thorson, J. T.

10.1101/2022.03.24.485545 — ecology — Posted on 2024-02-05

3954 Tadpoles rely on different sensory modalities for communication throughout development

Butler, J. M.; McKinney, J.; Ludington, S. C.; Mabogunje, M.; Baker, P.; Singh, D.; Edwards, S. V.; O'Connell, L. A.

10.1101/2022.10.18.512729 — developmental biology — Posted on 2024-02-05

3955 Brain and cancer associated binding domain mutations provide insight into CTCF's relationship with chromatin and its ability to act as a chromatin organizer

Do, C.; Jiang, G.; Cova, G.; Katsifis, C. C.; Narducci, D. N.; Yang, J.; Sakellaropoulos, T.; Vidal, R.; Lhoumaud, P.; Fara Regis, F.; Kakabadze, N.; Nora, E. P.; Noyes, M.; Cheng, X.; Hansen, A. S.; Skok, J. A.

10.1101/2024.01.11.575070 — molecular biology — Posted on 2024-02-05

3956 Development of a qPCR assay and a LAMP assay for Verticillium longisporum detection and a triplex qPCR assay for simultaneous detection of V. longisporum, Leptosphaeria biglobosa and L. maculans from canola samples

Fu, H.; Yang, Y.; Jiang, J.; Daniels, G.; Hill, B.; Xue, S.; Zahr, K.; Stellar, L.; Harding, M.; Feindel, D.; Bvindi, C.; Fernando, D.; Wang, L.; Feng, J.

10.1101/2024.01.24.577072 — microbiology — Posted on 2024-02-05

3957 Genomic and phylogenetic features of the Picobirnaviridae suggest microbial rather than animal hosts

Sadiq, S.; Holmes, E. C.; Mahar, J. E.

10.1101/2024.02.04.578841 — microbiology — Posted on 2024-02-05

3958 Sensory neurons regulate stimulus-dependent humoral immunity

Aguilar, D.; Zhu, F.; Millet, A.; Millet, N.; Germano, P.; Pisegna, J.; Doherty, T. A.; Swidergall, M.; Jendzjowsky, N.

10.1101/2024.01.04.574231 — immunology — Posted on 2024-02-05

3959 A dynamic neural resource model bridges sensory and working memory

Tomic, I.; Bays, P. M.

10.1101/2023.03.27.534406 — neuroscience — Posted on 2024-02-05

3960 Cyfip2 controls the acoustic startle threshold through FMRP, actin polymerization, and GABAB receptor function.

Deslauriers, J. C.; Ghotkar, R. P.; Russ, L. A.; Jarman, J. M.; Martin, R. M.; Tippett, R. G.; Sumathipala, S. H.; Burton, D. F.; Cole, D. C.; Marsden, K. C.

10.1101/2023.12.22.573054 — neuroscience — Posted on 2024-02-05

3961 Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states

Yao, J.; Dai, S.; Zhu, R.; Tan, J.; Zhao, Q.; Yin, Y.; Sun, J.; Du, X.; Ge, L.; Xu, J.; Hou, C.; Li, N.; Li, J.; Ji, W.; Zhu, C.; Zhang, R.; Li, T.

10.1101/2023.05.15.540723 — neuroscience — Posted on 2024-02-05

3962 Pan-cortical 2-photon mesoscopic imaging and neurobehavioral alignment in awake, behaving mice

Vickers, E. D.; McCormick, D. A.

10.1101/2023.10.19.563159 — neuroscience — Posted on 2024-02-05

3963 Rejuvenation of Senescent Cells by Low Frequency Ultrasound without Senolysis

Kureel, S. K.; Maroto, R.; Powell, S.; Margadant, F.; Blair, B.; Rasmussen, B.; Sheetz, M.

10.1101/2022.12.08.519320 — physiology — Posted on 2024-02-05

3964 Monocytic fibrocyte-like cell enrichment and myofibroblastic adaptation causes nucleus pulposus fibrosis and associates with disc degeneration severity

Sun, Y.; Peng, Y.; Su, Z.; So, K. K.; Lu, Q.; Lyu, M.; Zuo, J.; Huang, Y.; Guan, Z.; Cheung, K. M.; Zheng, Z.; Zhang, X.; Leung, V. Y.

10.1101/2024.01.16.575808 — physiology — Posted on 2024-02-05

3965 Epigenetic disruption of the RARγ complex impairs its function to bookmark AR enhancer interactions required for enzalutamide sensitivity in prostate cancer

Wani, S. A.; Hussain, S.; Gray, J. S.; Nayak, D.; Tang, H.; Perez, L. M.; Long, M. D.; Siddappa, M.; McCabe, C.; Campbell, L.; Freeman, M. R.; Campbell, M. J.

10.1101/2023.12.15.571947 — cancer biology — Posted on 2024-02-05

3966 Polymer-extracted structure of the mechanosensitive channel MscS reveals the role of protein-lipid interactions in the gating cycle

Moller, E.; Britt, M.; Zhou, F.; Yang, H.; Anishkin, A.; Ernst, R. K.; Sukharev, S. I.; Matthies, D.

10.1101/2024.01.22.576751 — biophysics — Posted on 2024-02-05

3967 Multiparameter-based photosynthetic state transitions of single phytoplankton cells

Harris, P. D.; Ben Eliezer, N.; Keren, N.; Lerner, E.

10.1101/2023.12.31.573751 — biophysics — Posted on 2024-02-05

3968 Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates

Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.; Zhang, B.

10.1101/2023.03.30.534967 — biophysics — Posted on 2024-02-05

3969 PxBLAT: An Efficient Python Binding Library for BLAT

Li, Y.; Yang, R.

10.1101/2023.08.02.551686 — bioinformatics — Posted on 2024-02-05

3970 Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learning

Laubscher, E.; Wang, X.; Razin, N.; Dougherty, T.; Xu, R.; Ombelets, L.; Pao, E.; Moffitt, J.; Yue, Y.; Van Valen, D. A.

10.1101/2023.09.03.556122 — bioinformatics — Posted on 2024-02-05

3971 Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness

Ingelman, H.; Heffernan, J. K.; Harris, A.; Brown, S. D.; Shaikh, K. M.; Yar Saqib, A.; Pinheiro, M. J.; de Lima, L. A.; Rodriguez Martinez, K.; Gonzalez-Garcia, R. A.; Hawkins, G.; Daleiden, J.; Tran, L.; Zeleznik, H.; Jensen, R. O.; Reynoso, V.; Schindel, H.; Jänes, J.; Simpson, S. D.; Köpke, M.; Marcellin, E.; Valgepea, K.

10.1101/2023.01.28.526018 — bioengineering — Posted on 2024-02-05

3972 Redox-dependent condensation and cytoplasmic granulation by human ssDNA binding protein 1 delineate roles in oxidative stress response

Harami, G. M.; Palinkas, J.; Kovacs, Z. J.; Jezso, B.; Tarnok, K.; Harami-Papp, H.; Hegedüs, J.; Mahmudova, L.; Kucsma, N.; Toth, S.; Szakacs, G.; Kovacs, M.

10.1101/2023.07.25.550517 — biochemistry — Posted on 2024-02-05

3973 Predicting and prioritizing community assembly: learning outcomes via experiments

Blonder, B. W.; Lim, M.; Godoy, O.

10.1101/2022.07.07.499099 — ecology — Posted on 2024-02-05

3974 Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling

Bolamperti, S.; Saito, H.; Heerdmann, S.; Hesse, E.; Taipaleenmaki, H.

10.1101/2023.11.04.565288 — cell biology — Posted on 2024-02-05

3975 BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A

Yang, R.; Chu, H.; Yue, H.; Mishina, Y.; Zhang, Z.; Liu, H.; Li, B.

10.1101/2023.10.03.560656 — cell biology — Posted on 2024-02-05

3976 Sphingolipids regulate the tethering stage of vacuole fusion by affecting membrane fluidity

Zhang, C.; Hurst, L. R.; Gokbayrak, Z. D.; Calderin, J. D.; Hrabak, M. R.; Balutowski, A.; Rivera-Kohr, D. A.; Kazmirchuk, T. D. D.; Brett, C. L.; Fratti, R. A.

10.1101/2020.02.17.953331 — cell biology — Posted on 2024-02-05

3977 Stability of influenza A virus in droplets and aerosols is heightened by the presence of commensal respiratory bacteria.

David, S. C.; Schaub, A.; Terrettaz, C.; Motos, G.; Costa, L.; Nolan, D. S.; Augugliaro, M.; Glas, I.; Pohl, M. O.; Klein, L. K.; Luo, B.; Bluvshtein, N.; Violaki, K.; Hugentobler, W.; Krieger, U. K.; Peter, T.; Stertz, S.; Nenes, A.; Kohn, T.

10.1101/2024.02.05.578881 — microbiology — Posted on 2024-02-05

3978 Probing the Link Between Vision and Language in Material Perception

Liao, C.; Sawayama, M.; Xiao, B.

10.1101/2024.01.25.577219 — neuroscience — Posted on 2024-02-05

3979 Complementary cognitive roles for D2-MSNs and D1-MSNs in interval timing

Bruce, R.; Weber, M. A.; Bova, A.; Volkman, R.; Jacobs, C.; Sivakumar, K.; Kim, Y.; Curtu, R.; Narayanan, N.

10.1101/2023.07.25.550569 — neuroscience — Posted on 2024-02-05

3980 Impaired updating of working memory representations in individuals with high BMI: evidence for dopaminergic mechanisms

Herzog, N.; Hartmann, H.; Janssen, L. K.; Kanyamibwa, A.; Waltmann, M.; Kovacs, P.; Deserno, L.; Fallon, S.; Villringer, A.; Horstmann, A.

10.1101/2023.11.03.565528 — neuroscience — Posted on 2024-02-05

3981 Impairment of the glial phagolysosomal system drives prion-like propagation in a Drosophila model of Huntington's disease

Davis, G. H.; Zaya, A.; Pearce, M. M. P.

10.1101/2023.10.04.560952 — neuroscience — Posted on 2024-02-05

3982 Fecundity Estimation of Atlantic mudskipper Periophthalmus barbarus in Ogbo-Okolo mangrove Forest of Santa Barbara River, Bayelsa State Niger Delta, Nigeria

Nathaniel, A. M.; Soberekon, I. J.; Gamage, I. E.; Eli, A. A.; Raimi, M. O.

10.1101/2024.02.01.578404 — zoology — Posted on 2024-02-05

3983 In vivo affinity maturation of the HIV-1 Env-binding domain of CD4

Pan, A.; Bailey, C. C.; Ou, T.; Xu, J.; Liu, X.; Hu, B.; Crynen, G.; Skamangas, N.; Bronkema, N.; Tran, M.; Mu, H.; Zhang, X.; Yin, Y.; Alpert, M. D.; He, W.; Farzan, M.

10.1101/2024.02.03.578630 — bioengineering — Posted on 2024-02-05

3984 Directing Cells to Murine Atherosclerotic Aortic Lesions via Targeting Inflamed Circulatory Interface using Nanocarriers

Liu, Z.-J.

10.1101/2024.02.02.578719 — bioengineering — Posted on 2024-02-05

3985 Autorepression of Yeast Hsp70 co-chaperones by intramolecular interactions involving their J-domains.

Rebeaud, M. E.; Tiwari, S.; Fauvet, B.; Mohr, A.; De Los Rios, P.; Goloubinoff, P.

10.1101/2024.02.05.578849 — biochemistry — Posted on 2024-02-05

3986 Mechanism of degrader-targeted protein ubiquitinability

Crowe, C.; Nakasone, M.; Chandler, S.; Tatham, M. H.; Makukhin, N.; Hay, R. T.; Ciulli, A.

10.1101/2024.02.05.578957 — biochemistry — Posted on 2024-02-05

3987 Defining the mechanisms and properties of post-transcriptional regulatory disordered regions by high-throughput functional profiling

Lobel, J. H.; Ingolia, N. T.

10.1101/2024.02.01.578453 — genomics — Posted on 2024-02-05

3988 Nanopore-based DNA long-read sequencing analysis of the aged human brain

Ramirez, P.; Sun, W.; Kazempour Dehkordi, S.; Zare, H.; Fongang, B.; Bieniek, K. F.; Frost, B.

10.1101/2024.02.01.578450 — genomics — Posted on 2024-02-05

3989 Characterizing and addressing error modes to improve sequencing accuracy

Kruglyak, S.; Altomare, A.; Ambroso, M.; Dien, V.; Lajoie, B. R.; Wiseman, K. N.; Levy, S. E.; Kellinger, M.

10.1101/2024.02.01.578321 — genomics — Posted on 2024-02-05

3990 Chromosome-scale genome assembly of the rough periwinkle Littorina saxatilis

De Jode, A.; Faria, R.; Formenti, G.; Sims, Y.; Smith, T.; Tracey, A.; Wood, J. M. D.; Zagrodzka, Z. B.; Johannesson, K.; Butlin, R. K.; Leder, E. H.

10.1101/2024.02.01.578480 — genomics — Posted on 2024-02-05

3991 HiCDiffusion - diffusion-enhanced, transformer-based prediction of chromatin interactions from DNA sequences

Chilinski, M.; Plewczynski, D.

10.1101/2024.02.01.578389 — genomics — Posted on 2024-02-05

3992 High-throughput nanopore DNA sequencing of large insert fosmid clones directly from bacterial colonies

Chuzel, L.; Sinha, A.; Cunningham, C. V.; Taron, C. H.

10.1101/2024.02.05.578990 — molecular biology — Posted on 2024-02-05

3993 Insights into the role of glycerophospholipids on the iron export function of SLC40A1 and the molecular mechanisms of ferroportin disease.

Debbiche, R.; Elbahnsi, A.; Uguen, K.; Ka, C.; Callebaut, I.; Le Gac, G.

10.1101/2024.02.05.578958 — molecular biology — Posted on 2024-02-05

3994 NEAT1 promotes genome stability via m6A methylation-dependent regulation of CHD4

Mamontova, V.; Trifault, B.; Gribling-Burrer, A.-S.; Bohn, P.; Preckwinkel, P.; Schmitz, W.; Gallant, P.; Papadopoulos, D.; Eilers, M.; Gutschner, T.; Smyth, R. P.; Burger, K.

10.1101/2024.02.05.578920 — molecular biology — Posted on 2024-02-05

3995 TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing

Bhuiyan, T.; Mendoza Sanchez, P. K.; Arecco, N.; Kim, J.; Nizamuddin, S.; Prunotto, A.; Tekman, M.; Biniossek, M. L.; Koidl, S.; Hugel, T.; Arnold, S. J.

10.1101/2024.02.05.578926 — molecular biology — Posted on 2024-02-05

3996 Genomic and phylogenetic features of the Picobirnaviridae suggest microbial rather than animal hosts

Sadiq, S.; Holmes, E. C.; Mahar, J. E.

10.1101/2024.02.04.578841 — microbiology — Posted on 2024-02-05

3997 CD40 Expression by B cells is Required for Optimal Immunity to Murine Pneumocystis Infection

Sassi, M.; Curran, S. J.; Bishop, L. R.; Lin, Y.; Kovacs, J.

10.1101/2024.02.05.578900 — microbiology — Posted on 2024-02-05

3998 Optimal Performance Objectives in the Highly Conserved Bone Morphogenetic Protein Signaling Pathway

Shaikh, R.; Larson, N. J.; Hanjaya-Putra, D.; Zartman, J. J.; Umulis, D. M.; Li, L.; Reeves, G. T.

10.1101/2024.02.01.578451 — systems biology — Posted on 2024-02-05

3999 Spotiflow: accurate and efficient spot detection for imaging-based spatial transcriptomics with stereographic flow regression

Dominguez Mantes, A.; Herrera, A.; Khven, I.; Schlaeppi, A.; Kyriacou, E.; Tsissios, G.; Aztekin, C.; Ligner, J.; La Manno, G.; Weigert, M.

10.1101/2024.02.01.578426 — bioinformatics — Posted on 2024-02-05

4000 Leveraging uncertainty quantification to optimise CRISPR guide RNA selection

Schmitz, C.; Bradford, J.; Salomone, R.; Perrin, D.

10.1101/2024.02.01.578527 — bioinformatics — Posted on 2024-02-05

4001 Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organism

Pimmett, V. L.; Douaihy, M.; Maillard, L.; Trullo, A.; Radulescu, O.; Lagha, M.

10.1101/2024.02.05.577724 — molecular biology — Posted on 2024-02-05

4002 Sparse CBX2 nucleates many Polycomb proteins to promote facultative heterochromatinization of Polycomb target genes

Ingersoll, S.; Trouth, A.; Luo, X.; Espinoza, A.; Wen, J.; Tucker, J.; Astatike, K.; Phiel, C. J.; Kutateladze, T. G.; WU, T. P.; Ramachandran, S.; Ren, X.

10.1101/2024.02.05.578969 — molecular biology — Posted on 2024-02-05

4003 XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants

Jain, S.; Kumar, S.; Lai, L.; Linderman, S.; Malik, A. A.; Ellis, M. L.; Godbole, S.; Solis, D.; Sahoo, M. K.; Bechnak, K.; Paredes, I.; Tanios, R.; Kazzi, B.; Dib, S. M.; Litvack, M. B.; Wimalsena, S. T.; Ciric, C.; Rostad, C.; West, R.; Teng, I.-T.; Wang, D.; Kwong, P. D.; Rouphael, N.; Pinsky, B. A.; Douek, D. C.; Wrammert, J.; Moreno, A.; Suthar, M. S.

10.1101/2024.02.03.578771 — immunology — Posted on 2024-02-05

4004 Capture and Release of Minke Whales Offers New Research Opportunities Including Measurements of Mysticete Hearing

Kleivane, L.; Kvadsheim, P. H.; Vinje, A. V. P.; Mulsow, J.; Olberg, R. A.; Teilmann, J.; Harms, C.; Houser, D.

10.1101/2024.02.02.577929 — physiology — Posted on 2024-02-05

4005 A Simple and Scalable Zebrafish Model of Sonic Hedgehog Medulloblastoma

Casey, M. J.; Chan, P. P.; Li, Q.; Jette, C. A.; Kohler, M.; Myers, B. R.; Stewart, R. A.

10.1101/2024.02.03.577834 — cancer biology — Posted on 2024-02-05

4006 TMEM16 and TMEM63/OSCA proteins share a conserved potential to permeate ions and phospholipids

Lowry, A.; Liang, P.; Wan, Y. C.; Pei, Z.-M.; Yang, H.; Zhang, Y.

10.1101/2024.02.04.578431 — biophysics — Posted on 2024-02-05

4007 Graspot: A graph attention network for spatial transcriptomics data integration with optimal transport

Gao, Z.; Cao, K.; Wan, L.

10.1101/2024.02.01.578505 — bioinformatics — Posted on 2024-02-05

4008 Voronota-LT: efficient, flexible and solvent-aware tessellation-based analysis of atomic interactions

Olechnovic, K.; Grudinin, S.

10.1101/2024.02.05.577169 — bioinformatics — Posted on 2024-02-05

4009 MAGIC matrices: freeform bioprinting materials to support complex and reproducible organoid morphogenesis

Graham, A. J.; Khoo, M. W. L.; Srivastava, V.; Viragova, S.; Parekh, K.; Morley, C. D.; Bird, M.; Lebel, P.; Kumar, S.; Klein, O. D.; Gomez-Sjoberg, R.; Gartner, Z. J.

10.1101/2024.02.01.578324 — bioengineering — Posted on 2024-02-05

4010 Functional 3'-UTR Variants Identify Regulatory Mechanisms Impacting Alcohol Use Disorder and Related Traits

Chen, A. B.; Yu, X.; Thapa, K. S.; Gao, H.; Reiter, J. L.; Xuei, X.; Tsai, A. P.; Landreth, G. E.; Lai, D.; Wang, Y.; Foroud, T. M.; Tischfield, J. A.; Edenberg, H. J.; Liu, Y.

10.1101/2024.01.31.578270 — genomics — Posted on 2024-02-05

4011 Nestling-care decisions by cooperatively breeding American Crows

Caffrey, C.; Peterson, C. C.; Hackler, T. W.

10.1101/2024.02.01.578448 — ecology — Posted on 2024-02-05

4012 Before and after delisting: population dynamics of North Atlantic humpback whales over two decades in the Gulf of Maine

10.1101/2024.02.04.577870 — ecology — Posted on 2024-02-05

4013 Cryosectioning-enabled super-resolution microscopy for studying nuclear architecture at the single protein level

Stein, J.; Ericsson, M.; Nofal, M.; Magni, L.; Aufmkolk, S.; McMillan, R. B.; Breimann, L.; Herlihy, C. P.; Lee, S. D.; Willemin, A.; Wohlmann, J.; Arguedas-Jimenez, L.; Yin, P.; Pombo, A.; Church, G. M.; Wu, C.-t.

10.1101/2024.02.05.576943 — cell biology — Posted on 2024-02-05

4014 Mapping changes in uterine contractility during the ovulatory cycle with wide-area calcium imaging in live mice.

Combs, D. J.; Moult, E. M.; England, S. K.; Cohen, A. E.

10.1101/2024.02.02.578395 — physiology — Posted on 2024-02-05

4015 Forseti: A mechanistic and predictive model of the splicing status of scRNA-seq reads

He, D.; Gao, Y.; Chan, S. S.; Quintana-Parrilla, N.; Patro, R.

10.1101/2024.02.01.577813 — bioinformatics — Posted on 2024-02-05

4016 Identification of differentially methylated single-nucleotide m6A sites by incorporating site-specific antibody specificity

Guo, Y.; Wu, Z.; Cheng, W.; Ren, Z.; Cun, Y.; Wang, J.

10.1101/2024.02.04.578119 — bioinformatics — Posted on 2024-02-05

4017 SEraster: a rasterization preprocessing framework for scalable spatial omics data analysis

Aihara, G.; Clifton, K.; Chen, M.; Atta, L.; Miller, B. F.; Fan, J.

10.1101/2024.02.01.578436 — bioinformatics — Posted on 2024-02-05

4018 Prolonged airway explant culture enables study of health, disease, and viral pathogenesis

Lee-Ferris, R. E.; Okuda, K.; Galiger, J. R.; Schworer, S. A.; Rogers, T. D.; Dang, H.; Gilmore, R.; Edwards, C.; Nakano, S.; Cawley, A. M.; Pickles, R. J.; Gallant, S. C.; Crisci, E.; Rivier, L.; Hagood, J. S.; O'Neal, W. K.; Baric, R. S.; Grubb, B. R.; Boucher, R. C.; Randell, S. H.

10.1101/2024.02.03.578756 — bioengineering — Posted on 2024-02-05

4019 Enzyme Bioink for the 3D Printing of Biocatalytic Materials

Altevogt, L. A.; Sheikh, R. H.; Molley, T. G.; Yong, J.; Liang, K.; Spicer, P.; Kilian, K. A.; Wich, P. R.

10.1101/2024.02.04.577699 — bioengineering — Posted on 2024-02-05

4020 Maximum Likelihood Estimation for Unrooted 3-Leaf Trees: An Analytic Solution for the CFN Model

Hill, M.; Roch, S.; Rodriguez, J. I.

10.1101/2024.02.01.578504 — evolutionary biology — Posted on 2024-02-05

4021 Genomic insights into photosymbiotic evolution in Tridacna squamosa

Zhang, Y.; Mao, F.; Li, Y.; Wong, N.-K.; Bao, Y.; Dai, H.; Sun, J.; Yi, W.; Xiao, S.; Xiang, Z.; Li, J.; Zhang, Y.; Xia, X.; Zhang, L.; Zhou, H.; Yu, Z.

10.1101/2024.02.04.577604 — evolutionary biology — Posted on 2024-02-05

4022 Individual contributions to nest building and incubation by cooperatively breeding American Crows

Peterson, C. C.; Hackler, T. W.; Caffrey, C.

10.1101/2024.02.01.578444 — ecology — Posted on 2024-02-05

4023 The first chicken oocyte nucleus whole transcriptomic profile defines the spectrum of maternal mRNA and non-coding RNA genes transcribed by the lampbrush chromosomes

Krasikova, A.; Kulikova, T.; Schelkunov, M.; Makarova, N.; Fedotova, A.; Berngardt, V.; Maslova, A.; Fedorov, A.

10.1101/2024.02.05.577752 — cell biology — Posted on 2024-02-05

4024 A POLR3B-variant reveals a Pol III transcriptome response dependent on La protein/SSB

Mattijssen, S.; Kerkhofs, K.; Stephen, J.; Yang, A.; Han, C. G.; Tadafumi, Y.; Iben, J. R.; Mishra, S.; Sakhawala, R. M.; Ranjan, A.; Gowda, M.; Gahl, W. A.; Gu, S.; Malicdan, M. C.; Maraia, R. J.

10.1101/2024.02.05.577363 — molecular biology — Posted on 2024-02-05

4025 Unprocessed Genomic Uracil as a Source of DNA Replication Stress in Cancer Cells

Saxena, S.; Patel, P. S.; Nabel, C. S.; Kawale, A. S.; Crosby, C. R.; Vander Heiden, M. G.; Hata, A. N.; Zou, L.

10.1101/2024.02.05.578390 — molecular biology — Posted on 2024-02-05

4026 Tamm-Horsfall protein augments neutrophil NETosis during urinary tract infection

Mercado-Evans, V.; Chew, C.; Serchejian, C.; Saltzman, A.; Mejia, M.; Zulk, J.; Cornax, I.; Nizet, V.; Patras, K.

10.1101/2024.02.01.578501 — immunology — Posted on 2024-02-05

4027 DNA Prime-Protein Boost Targeting Conformational Non-RBD Region for Broad Cross-Neutralization

Ma, Y.-F.; Chen, K.; Xie, B.; Zhu, J.; He, X.; Chen, C.; Yang, Y. R.; Liu, Y.

10.1101/2024.02.04.578544 — immunology — Posted on 2024-02-05

4028 Effect of environmental conditions on the wing morphometric variation in Aedes aegypti (Diptera: Culicidae) in India

Sharma, G.; Sarma, D. K.; Bhutiani, R.

10.1101/2024.02.01.578359 — zoology — Posted on 2024-02-05

4029 The accomplices: Heparan sulfates and N-glycans foster SARS-CoV-2 spike:ACE2 receptor binding and virus priming

Paiardi, G.; Ferraz, M.; Rusnati, M.; Wade, R. C.

10.1101/2024.02.05.578888 — biophysics — Posted on 2024-02-05

4030 BiaPy: A unified framework for versatile bioimage analysis with deep learning

Franco-Barranco, D.; Andres-San Roman, J. A.; Hidalgo-Cenalmor, I.; Backova, L.; Gonzalez-Marfil, A.; Caporal, C.; Chessel, A.; Gomez-Galvez, P.; Escudero, L. M.; Wei, D.; Munoz-Barrutia, A.; Arganda-Carreras, I.

10.1101/2024.02.03.576026 — bioinformatics — Posted on 2024-02-05

4031 Identification of transcriptional regulators using a combined disease module identification and prize-collecting Steiner tree approach

Galindez, G.; Lopez, B. A.; Blumenthal, D. B.; Kacprowski, T.

10.1101/2024.02.05.577574 — bioinformatics — Posted on 2024-02-05

4032 Nix coordinates nuclear calcium signaling to modulate the muscle phenotype.

Field, J. T.; Chapman, D.; Ghavami, S.; West, A. R.; Saleem, A.; Kindrachuk, J.; Triggs-Raine, B.; Gordon, J. W.

10.1101/2023.03.18.532760 — cell biology — Posted on 2024-02-05

4033 Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour

Bosworth, M.; Isles, A.; Wilkinson, L.; Humby, T.

10.1101/2021.12.10.471949 — neuroscience — Posted on 2024-02-05

4034 Serotonergic and dopaminergic neurons in the dorsal raphe are differentially altered in a mouse model for parkinsonism.

Boi, L.; Johansson, Y.; Tonini, R.; Moratalla, R.; Fisone, G.; Silberberg, G.

10.1101/2023.07.21.550014 — neuroscience — Posted on 2024-02-05

4035 In-vivo distributed multicellular control of gene expression in microbial consortia

Salzano, D.; Shannon, B.; Grierson, C.; Marucci, L.; Savery, N.; di Bernardo, M.

10.1101/2023.11.13.566807 — synthetic biology — Posted on 2024-02-05

4036 OsNF-YB7 inactivates OsGLK1 to inhibit chlorophyll biosynthesis in rice embryo

Yang, Z.; Bai, T.; E, Z.; Niu, B.; Chen, C.

10.1101/2024.02.05.578907 — plant biology — Posted on 2024-02-05

4037 APCalign: an R package workflow and app for aligning and updating flora names to the Australian Plant Census

Wenk, E. H.; Cornwell, W.; Fuchs, A.; Kar, F.; Monro, A.; Sauquet, H.; Stephens, R. E.; Falster, D. S.

10.1101/2024.02.02.578715 — plant biology — Posted on 2024-02-05

4038 Improving rice drought tolerance through host-mediated microbiome selection

Styer, A.; Pettinga, D.; Caddell, D. F.; Coleman-Derr, D.

10.1101/2024.02.03.578672 — plant biology — Posted on 2024-02-05

4039 Spatial transcriptomics reveals distinct lineage identities for major and minor vein initiation during maize leaf development

Perico, C.; Zaidem, M.; Sedelnikova, O.; Bhattacharya, S.; Korfhage, C.; Langdale, J. A.

10.1101/2024.02.05.578898 — plant biology — Posted on 2024-02-05

4040 Medicago truncatula ABCG40 is a cytokinin importer that negatively regulates lateral root density and nodule number

Jamruszka, T.; Banasiak, J.; Pawela, A.; Jarzyniak, K.; Xia, J.; Biala, W.; Plackova, L.; Tsering, T.; Iacobini, F. R.; Novak, O.; Geisler, M. M.; Jasinski, M.

10.1101/2022.11.10.516000 — plant biology — Posted on 2024-02-05

4041 GOAT: efficient and robust identification of geneset enrichment

Koopmans, F.

10.1101/2023.12.10.570979 — bioinformatics — Posted on 2024-02-05

4042 Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system

Zhou, F.; Bocetti, J. M.; Hou, M.; Qin, D.; Hinnebusch, A. G.; Lorsch, J. R.

10.1101/2023.10.16.562452 — biochemistry — Posted on 2024-02-05

4043 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon

Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.

10.1101/2023.09.25.559196 — genomics — Posted on 2024-02-05

4044 The first chromosome-level annotated reference genome for Chrosomus eos, the northern redbelly dace

Schultz, B.; Mandeville, E. G.

10.1101/2023.12.21.572839 — genomics — Posted on 2024-02-05

4045 Changes in length-at-first return of a sea trout (Salmo trutta) population in northern France

Josset, Q.; Beaulaton, L.; Romakkaniemi, A.; Nevoux, M.

10.1101/2023.11.21.568009 — ecology — Posted on 2024-02-05

4046 Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses

Gilbert-girard, S.; Piret, J.; Carbonneau, J.; Henaut, M.; Goyette, N.; Boivin, G.

10.1101/2024.02.02.578538 — microbiology — Posted on 2024-02-05

4047 A lactate-dependent shift of glycolysis mediates synaptic and cognitive processes

Fernandez-Moncada, I.; Lavanco, G.; B. Fundazuri, U.; Bollmohr, N.; Mountadem, S.; Hachaguer, P.; Julio-Kalajzic, F.; Gisquet, D.; Dalla Tor, T.; Serrat, R.; Bellocchio, L.; Cannich, A.; Fortunato-Marsol, B.; Nasu, Y.; Campbell, R. E.; Drago, F.; Cannizzaro, C.; Bouzier-Sore, A.-K.; Ferreira, G.; Pellerin, L.; Bolanos, J. P.; Bonvento, G.; Barros, L. F.; Oliet, S. H. R.; Panatier, A.; Marsicano, G.

10.1101/2023.03.15.532748 — neuroscience — Posted on 2024-02-05

4048 Geometry and cell wall mechanics guide early pollen tube growth in Arabidopsis thaliana

Riglet, L.; Quilliet, C.; Godin, C.; John, K.; Fobis-Loisy, I.

10.1101/2024.02.05.578915 — plant biology — Posted on 2024-02-05

4049 SYNERGISTIC ANTITUMOR EFFECT OF NAPROXEN AND SORAFENIB IN HEPATOCELLULAR CARCINOMA

Akar, E.; Unsal Beyge, S.; Kahraman, D. C.

10.1101/2024.02.01.578341 — cancer biology — Posted on 2024-02-05

4050 Sex-Specific Development of ssRNA Virus Receptor Gene Expression in the Human Brain

Halabian, N.; Monteiro, L.; Li, J.; Panday, M.; Murphy, K.

10.1101/2023.10.11.561925 — neuroscience — Posted on 2024-02-05

4051 Understanding Regeneration: investigating the apical notch and meristem re-emergence in Marchantia polymorpha

Marron, A. O.; Rebmann, M.; Delmans, M.; Haseloff, J. O.

10.1101/2024.02.04.575544 — plant biology — Posted on 2024-02-05

4052 WITHDRAWN: The Molecular Signature Associated with Oxaliplatin-Induced Peripheral Neuropathy in Colorectal Cancer

Modekurty, S.

10.1101/2024.01.21.576583 — bioinformatics — Posted on 2024-02-05

4053 Comparison of urinary proteome in the first two days after mating in male rats

Gao, Y.; Wang, H.; Zhao, C.

10.1101/2023.11.18.567698 — biochemistry — Posted on 2024-02-05

4054 Significance of Evolutionary Lags in the Primate Brain Size/Body Size Relationship

Dunbar, R. I. M.

10.1101/2024.02.05.578865 — evolutionary biology — Posted on 2024-02-05

4055 Insect population dynamics under Wolbachia-induced cytoplasmic incompatibility: puzzle more than buzz in Drosophila suzukii

Auguste, A.; Ris, N.; Belgaidi, Z.; Kremmer, L.; Mouton, L.; Fauvergue, X.

10.1101/2023.08.02.551598 — ecology — Posted on 2024-02-05

4056 Acquiring social safety engages oxytocin neurons in the supraoptic nucleus - role of Magel2 deficiency

Chakraborty, P.; Lamat, H.; Andre, E. M.; Fontanaud, P.; Jeanneteau, F.

10.1101/2024.02.04.578818 — neuroscience — Posted on 2024-02-05

4057 Prior probability cues bias sensory encoding with increasing task exposure

Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.

10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-02-05

4058 Inflammation and autophagy dysfunction in metachromatic leukodystrophy: a central role for mTOR?

Catchpole, Z.; Hartanto, A. E.; Kataura, T.; Palmowski, P.; Porter, A.; Ulicna, K.; McFarland, R.; Pyle, A.; Taylor, R.; Harris, K. S.; Korolchuk, V. I.; Erskine, D.

10.1101/2023.09.14.557720 — neuroscience — Posted on 2024-02-05

4059 Local translation is engaged to sustain synaptic function in impaired Wallerian degeneration

Paglione, M.; Restivo, L.; Zakhia, S.; Llobet Rosell, A.; Terenzio, M.; Neukomm, L. J.

10.1101/2023.08.18.553870 — neuroscience — Posted on 2024-02-05

4060 PerturBase: a comprehensive database for single-cell perturbation data analysis and visualization

Liu, Q.; Guo, L.; Wei, Z.; Si, D.; Duan, B.; Gao, Y.; Yu, Q.

10.1101/2024.02.03.578767 — cell biology — Posted on 2024-02-05

4061 Pharmacological control of CAR T cells through CRISPR-driven rapamycin resistance

Levesque, S.; Carleton, G.; Duque, V.; Goupil, C.; Fiset, J.-P.; Villeneuve, S.; Normandeau, E.; Morin, G.; Dumont, N.; Nelson, B. H.; Laganiere, J.; Boyle, B.; Lum, J. J.; Doyon, Y.

10.1101/2023.09.14.557485 — cancer biology — Posted on 2024-02-05

4062 Pre-training with pseudo-labeling for regulatory sequence prediction

Mourad, R.

10.1101/2023.12.21.572780 — bioinformatics — Posted on 2024-02-05

4063 Depth-dependent scaling of axial distances in light microscopy

Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.

10.1101/2024.01.31.578242 — biophysics — Posted on 2024-02-05

4064 Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics

Nara, T.; Takahashi, H.; Awazu, A.; Kikuchi, Y.

10.1101/2024.01.27.577362 — bioinformatics — Posted on 2024-02-05

4065 Tumor-derived hypoxic small extracellular vesicles promote endothelial cell migration and tube formation via ALS2/Rab5/β-catenin signaling

Silva, P.; Hernandez, N.; Tapia, H.; Gaete, B.; Flores, T.; Herrera, D.; Caceres, A.; Varas, M.; Torres, V. A.

10.1101/2024.02.02.578446 — cell biology — Posted on 2024-02-05

4066 Architecture of intact mammalian pyruvate dehydrogenase complex revealed by in-situ structural analysis

Wang, C.; Ma, C.; Chang, S.; Wu, H.; Yan, C.; Chen, J.; Wu, Y.; An, S.; Xu, J.; Han, Q.; Jiang, Y.; Jiang, Z.; Gao, H.; Zhang, X.; Chang, Y.

10.1101/2024.02.01.578502 — cell biology — Posted on 2024-02-05

4067 Ca2+-sensor ALG-2 engages ESCRTs to enhance lysosomal membrane resilience to osmotic stress

Chen, W.; Motsinger, M. M.; Li, J.; Bohannon, K. P.; Hanson, P. I.

10.1101/2024.02.04.578682 — cell biology — Posted on 2024-02-05

4068 Spatiotemporal Clusters of ERK Activity Coordinate Cytokine-induced Inflammatory Responses in Human Airway Epithelial Cells

DeCuzzi, N. L.; Oberbauer, D.; Chmiel, K. J.; Pargett, M.; Ferguson, J. M. A.; Murphy, D.; Zeki, A. A.; Albeck, J. G.

10.1101/2024.02.03.578773 — cell biology — Posted on 2024-02-05

4069 Single-cell and bulk transcriptional profiling of mouse ovaries reveals novel genes and pathways associated with DNA damage response in oocytes.

Mills, M. L.; Emori, C.; Kumar, P.; Boucher, Z.; George, J.; Bolcun-Filas, E.

10.1101/2024.02.02.578648 — cell biology — Posted on 2024-02-05

4070 Deriving the cone fundamentals: a subspace intersection method

Wandell, B. A.; Goossens, T.; Brainard, D. H.

10.1101/2024.02.04.577470 — neuroscience — Posted on 2024-02-05

4071 Visual stimulation drives retinotopic acetylcholine release in the mouse visual cortex

Knudstrup, S. G.; Martinez-Reyes, C.; Rauscher, B.; Doran, P. R.; Fomin-Thunemann, N.; Kılıc, K.; Jiang, J. X.; Devor, A.; Thunemann, M.; Gavornik, J. P.

10.1101/2024.02.04.578821 — neuroscience — Posted on 2024-02-05

4072 A call for a unified and multimodal definition of cellular identity in the enteric nervous system

Majd, H.; Cesiulis, A.; Samuel, R. M.; Richter, M. N.; Elder, N.; Guyer, R. A.; Hao, M.; Stamp, L.; Goldstein, A.; Fattahi, F.

10.1101/2024.01.15.575794 — neuroscience — Posted on 2024-02-05

4073 Inner hair cell synapse density influences auditory processing

Ji, L.; Borges, B. C.; Martel, D. T.; Wu, C.; Liberman, M. C.; Shore, S. E.; Corfas, G.

10.1101/2022.05.02.490340 — neuroscience — Posted on 2024-02-05

4074 The role of ultradian rhythms in post-deprivationrebounds and diurnal rhythms of sleep and wakefulness in rats

Lim, J.; Stephenson, R.

10.1101/2024.02.04.578825 — animal behavior and cognition — Posted on 2024-02-05

4075 Oxidative stress induces release of mitochondrial DNA into the extracellular space in human placental villous trophoblast BeWo cells

Gardner, J. J.; Cushen, S. C.; Silva, R. d. N.; Bradshaw, J. L.; Hula, N.; Gorham, I. K.; Tucker, S. M.; Zhou, Z.; Cunningham, R. L.; Phillips, N. R.; Goulopoulou, S.

10.1101/2024.02.02.578433 — cell biology — Posted on 2024-02-04

4076 A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and tankyrase

Vu, J. T.; Tavasoli, K. U.; Mandjikian, L.; Sheedy, C. J.; Bacal, J.; Morrissey, M. A.; Richardson, C. D.; Gardner, B. M.

10.1101/2024.02.02.578667 — cell biology — Posted on 2024-02-04

4077 Regulatory role of cholesterol in modulating actin dynamics and cell adhesive interactions in the trabecular meshwork

Wang, T.; Kimmel, H. R.; Park, C.; Ryoo, H. P.; Liu, J.; Underhill, G.; Pattabiraman, P. P.

10.1101/2024.02.02.578717 — cell biology — Posted on 2024-02-04

4078 SMCHD1 activates the expression of genes required for the expansion of human myoblasts

Wong, M. M.-K.; Gardner, E.; Megeney, L. A.; Emerson, C. P.; Gabellini, D. P.; Dilworth, J.

10.1101/2024.02.04.578809 — cell biology — Posted on 2024-02-04

4079 Microgroove substrates unveil topography-driven, dynamic 3D nuclear deformations

Leclech, C.; Roellinger, B.; Frederick, J.; Mamchaoui, K.; Coirault, C.; Barakat, A. I.

10.1101/2024.02.02.578638 — cell biology — Posted on 2024-02-04

4080 BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

Chen, B.; Lynn-Nguyen, T. M.; Jadhav, P.; Halligan, B. S.; Rossiter, N. J.; Guerra, R. M.; Koshkin, S.; Koo, I.; Morlacchi, P.; Hanna, D. A.; Lin, J.; Banerjee, R.; Pagliarini, D.; Patterson, A. D.; Mosalaganti, S.; Sexton, J.; Cali, T.; Lyssiotis, C. A.; Shah, Y. M.

10.1101/2024.02.02.578646 — cell biology — Posted on 2024-02-04

4081 Substrate Stiffness Reshapes Layer Architecture and Biophysical Features of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential

LLEWELLYN, J.; CHARRIER, A.; HELFER, E.; DONO, R.

10.1101/2024.02.01.578393 — cell biology — Posted on 2024-02-04

4082 Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells

Liang, Z.; Ralph-Epps, T.; Schmidtke, M. W.; Lazcano, P.; Denis, S. W.; Balazova, M.; Chakkour, M.; Hazime, S.; Ren, M.; Schlame, M.; Houtkooper, R.; Greenberg, M.

10.1101/2024.02.03.578755 — cell biology — Posted on 2024-02-04

4083 Human Amniotic Epithelial Cells Promote Chx10-/Pax6+ Muller Glia Subpopulation Reprogramming into Photoreceptor-like Cells

Gao, H.; Yin, Z.; Huang, X.; Zeng, Y.; Zou, T.; A, L.; Zhe, C.; Cheng, X.; Ge, L.; Kang, J.; Lin, X.; Gong, H.; Xie, J.; Fan, X.; xu, H.

10.1101/2024.02.01.578388 — cell biology — Posted on 2024-02-04

4084 TIAM1 signaling drives prostatic budding and branching phenotypes and is a potential therapeutic target for BPH

Khedmatgozar, H.; Dutta, S.; Dominguez, M.; Latour, D.; Johnson, M.; Fokar, M.; Warraich, I.; DeRiese, W.; Haynes, A.; Matusik, R. J.; Brandi, L.; Nandana, S.; Tripathi, M.

10.1101/2024.02.02.578055 — cell biology — Posted on 2024-02-05

4085 Phosphoproteomic investigation of targets of protein phosphatases in EGFR signaling

Eguchi, A.; Olsen, J. V.

10.1101/2024.02.01.578427 — cell biology — Posted on 2024-02-05

4086 Derivation and simulation of a computational model of active cell populations: How overlap avoidance, deformability, cell-cell junctions and cytoskeletal forces affect alignment

Leech, V.; Kenny, F.; Marcotti, S.; Shaw, T.; Stramer, B.; Manhart, A.

10.1101/2024.02.02.578535 — cell biology — Posted on 2024-02-05

4087 High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension

Shinohara, T.; Moonen, J.-R. A. J.; Chun, Y. H.; Lee-Yow, Y. C.; Okamura, K.; Szafron, J. M.; Kaplan, J.; Cao, A.; Wang, L.; Taylor, S.; Isobe, S.; Dong, M.; Yang, W.; Guo, K.; Franco, B. D.; Pacharinsak, C.; Pisani, L. J.; Saitoh, S.; Mitani, Y.; Marsden, A. L.; Engreitz, J.; Korbelin, J.; Rabinovitch, M.

10.1101/2024.02.02.578526 — cell biology — Posted on 2024-02-05

4088 Formation of a giant unilocular vacuole via macropinocytosis-like process confers anoikis resistance

Kim, J.; Kim, D.; Kim, D.-K.; Lee, S.-H.; Jang, W.; Lim, D.-S.

10.1101/2024.01.31.578296 — cell biology — Posted on 2024-02-05

4089 Endothelial PHD2 deficiency induces apoptosis resistance and inflammation via AKT activation and AIP1 loss independent of HIF2α

Wang, S.; Awad, K. S.; Chen, L.-Y.; Siddique, M. A. H.; Ferreyra, G. A.; Wang, C. L.; Joseph, T.; Yu, Z.-X.; Takeda, K.; Demirkale, C. Y.; Zhao, Y.; Elinoff, J. M.; Danner, R. L.

10.1101/2024.02.01.578286 — cell biology — Posted on 2024-02-05

4090 Hypoxia and TNF-alpha modulate extracellular vesicle release from human induced pluripotent stem cell-derived cardiomyocytes

Viola, M.; Bebelman, M. P.; Maas, R. G. C.; Verweij, F. J.; Seinen, C. S.; de Jager, S. C. A.; Vader, P.; Pegtel, D. M.; Sluijter, J. P. G.

10.1101/2024.02.01.578434 — cell biology — Posted on 2024-02-05

4091 OPA1 and disease-causing mutants perturb mitochondrial nucleoid distribution

Macuada, J.; Molina-Riquelme, I.; Vidal, G.; Perez-Bravo, N.; Vasquez-Trincado, C.; Aedo, G.; Lagos, D.; Horvath, R.; Rudge, T. J.; Cartes-Saavedra, B.; Eisner, V.

10.1101/2024.02.01.578418 — cell biology — Posted on 2024-02-05

4092 Modeling Normal Mouse Uterine Contraction and Placental Perfusion with Non- invasive Longitudinal Dynamic Contrast Enhancement MRI

Cortes, D. R. E.; Stapleton, M. C.; Schwab, K. E.; West, D.; Coulson, N. W.; O'Donnell, M. G.; Powers, R. W.; Wu, Y.

10.1101/2024.01.31.577398 — systems biology — Posted on 2024-02-04

4093 Combining systems and synthetic biology for in vivo enzymology

Castano-Cerezo, S.; Chamas, A.; Kulyk, H.; Treitz, C.; Bellvert, F.; Tholey, A.; Galeote, V.; Camarasa, C.; Heux, S.; Garcia-Alles, L. F.; Millard, P.; Truan, G.

10.1101/2024.02.02.578620 — systems biology — Posted on 2024-02-04

4094 Germinal center BCR maturation in appendicitis reveals a role for antigen-specific adaptive immune responses during disease

Stewart, E.; Taghvaei, Z.; Leon, C.; Shapiro, J.; Zhu, L.; Alpert, L.; Turaga, K.; Roy Chowdhury, R.

10.1101/2024.01.31.578312 — immunology — Posted on 2024-02-04

4095 Genetically defined nucleus incertus neurons differ in connectivity and function

Spikol, E. D.; Cheng, J.; Macurak, M.; Subedi, A.; Halpern, M. E.

10.1101/2022.04.07.487414 — neuroscience — Posted on 2024-02-04

4096 Identifying the factors governing internal state switches during nonstationary sensory decision-making

Mohammadi, Z.; Ashwood, Z. C.; International Brain Laboratory, ; Pillow, J. W.

10.1101/2024.02.02.578482 — neuroscience — Posted on 2024-02-04

4097 Functional Modification of Cyanobacterial Phycobiliprotein and Phycobilisomes through Bilin Metabolism Control

Sato, M.; Kawaguchi, T.; Maeda, K.; Watanabe, M.; Ikeuchi, M.; Narikawa, R.; Watanabe, S.

10.1101/2024.02.04.578791 — synthetic biology — Posted on 2024-02-04

4098 MIOSTONE: Modeling microbiome-trait associations withtaxonomy-adaptive neural networks

Jiang, Y.; Atton, M.; Zhu, Q.; Lu, Y.

10.1101/2023.11.04.565596 — bioinformatics — Posted on 2024-02-04

4099 Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.

Lee, J. D.; Won, W.; Kimball, K.; Wang, Y.; Yeboah, F.; Evitts, K.; Neiswanger, C.; Schattauer, S.; Rappleye, M.; Bremner, S. B.; Chun, C.; Smith, N.; Mack, D. L.; Young, J. E.; Lee, C. J.; Chavkin, C.; Berndt, A.

10.1101/2024.01.31.578117 — bioengineering — Posted on 2024-02-04

4100 A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine

Walton, B. L.; Shattuck-Brandt, R.; Hamann, C. A.; Tung, V. W.; Colazo, J. M.; Brand, D. D.; Hasty, K. A.; Duvall, C. L.; Brunger, J. M.

10.1101/2024.01.31.578281 — bioengineering — Posted on 2024-02-04

4101 Multiplex Single-Cell Bioprinting for Engineering of Heterogeneous Tissue Constructs with Subcellular Spatial Resolution

Helms, H. R.; Oyama, K. A.; Ware, J. P.; Ibsen, S. D.; Bertassoni, L. E.

10.1101/2024.02.01.578499 — bioengineering — Posted on 2024-02-04

4102 An ECM scaffold combined with a compliant 3D printed spring-shaped reinforcement for cartilage engineering applications

Solorzano Requejo, W.; Limones Ahijon, B.; Corchado, C.; Llorca, J.; Diaz Lantada, A.; Patterson, J.; Diaz-Payno, P. J.

10.1101/2024.01.31.575642 — bioengineering — Posted on 2024-02-04

4103 Pesticide chemical leads inhibiting protein-protein interactions

Ben Shushan, R. S.; Cohen, E.; Ben Naim, N.; Amram, E.; Gressel, J.; Peleg, D.; Dotan, N.; Bloch, I.; Gal, M.

10.1101/2024.02.03.578754 — biochemistry — Posted on 2024-02-04

4104 Risking your Tail: Modeling Individual Differences in Risk-sensitive Exploration using Conditional Value at Risk and Bayes Adaptive Markov Decision Processes

Shen, T.; Dayan, P.

10.1101/2024.01.07.574574 — animal behavior and cognition — Posted on 2024-02-04

4105 SOLUBILIZER OF BACTERIAL ORIGIN SURFACTIN INCREASES THE BIOLOGICAL ACTIVITY OF C60 FULLERENE

Emelyantsev, S.; Prazdnova, E.; Chistyakov, V.

10.1101/2023.12.06.569891 — genetics — Posted on 2024-02-04

4106 Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

Contento, G.; Wilson, J.-A. A.; Selvarajah, B.; Plate, M.; Guillotin, D.; Morales, V.; Trevisani, M.; Pitozzi, V.; Bianchi, K.; Chambers, R. C.

10.1101/2024.01.30.577965 — cell biology — Posted on 2024-02-04

4107 Unbiased, Cell-free Profiling of Single Influenza Genomes at High-throughput

Cowell, T. W.; Puryear, W.; Chen, C.-L.; Ding, R.; Runstadler, J.; Han, H.-S.

10.1101/2024.02.03.578479 — molecular biology — Posted on 2024-02-04

4108 A neutral process of genome reduction in marine bacterioplankton

Wang, X.; Xie, M.; Ho, K. E. Y. K.; Sun, Y.; Chu, X.; Zhang, S.; Ringel, V.; Wang, H.; Zhang, X.-H.; Shao, Z.; Zhao, Y.; Brinkhoff, T.; Petersen, J.; Wagner-Döbler, I.; Luo, H.

10.1101/2024.02.04.578831 — microbiology — Posted on 2024-02-04

4109 Genomic and environmental controls on Castellaniella biogeography in an anthropogenically disturbed subsurface

Goff, J. L.; Szink, E. G.; Durrence, K. L.; Lui, L. M.; Nielsen, T. N.; Kuehl, J. V.; Hunt, K. A.; Chandonia, J.-M.; Huang, J.; Thorgersen, M. P.; Poole, F. L.; Stahl, D. A.; Chakraborty, R.; Deutschbauer, A. M.; Arkin, A. P.; Adams, M. W. W.

10.1101/2024.02.03.578758 — microbiology — Posted on 2024-02-04

4110 Variant Surface Protein GP60 Contributes to Host Infectivity of Cryptosporidium parvum

Li, M.; Yang, F.; Hou, T.; Gong, X.; Li, N.; Sibley, L. D.; Feng, Y.; Xiao, L.; Guo, Y.

10.1101/2024.02.04.578776 — microbiology — Posted on 2024-02-04

4111 Time resolved multi-omics reveals diverse metabolic strategies of Salmonella during diet-induced inflammation

Kokkinias, K.; Sabag-Daigle, A.; Kim, Y.; Leleiwi, I.; Shaffer, M.; Kevorkian, R.; Daly, R. A.; Wysocki, V. H.; Borton, M. A.; Ahmer, B. M. M.; Wrighton, K. C.

10.1101/2024.02.03.578763 — microbiology — Posted on 2024-02-04

4112 Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites.

Koussis, K.; Haase, S.; Withers-Martinez, C.; Flynn, H. R.; Kunzelmann, S.; Christodoulou, E.; Ibrahim, F.; Skehel, M.; Baker, D. A.; Blackman, M. J.

10.1101/2024.02.04.578801 — microbiology — Posted on 2024-02-04

4113 Single cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes

G V S, D.; Dani, A.

10.1101/2024.01.08.574704 — neuroscience — Posted on 2024-02-04

4114 Structured Peer Review: Pilot results from 23 Elsevier Journals

Malicki, M.; Mehmani, B.

10.1101/2024.02.01.578440 — scientific communication and education — Posted on 2024-02-04

4115 Matrix confinement modulates 3D spheroid sorting and burst-like collective migration

Cai, G.; Li, X.; Lin, S.-S.; Chen, S. J.; Rodgers, N. C.; Koning, K. M.; Bi, D.; Liu, A. P.

10.1101/2023.07.23.549940 — biophysics — Posted on 2024-02-04

4116 Cactus: a user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis

Salignon, J.; Millan-Arino, L.; Garcia, M.; Riedel, C. G.

10.1101/2023.05.11.540110 — bioinformatics — Posted on 2024-02-04

4117 Identifying distinct neural features between the initial and corrective phases of precise reaching using AutoLFADS

Lee, W.-H.; Karpowicz, B. M.; Pandarinath, C.; Rouse, A. G.

10.1101/2023.06.30.547252 — bioengineering — Posted on 2024-02-04

4118 Tunable Macroscopic Alignment of Self-Assembling Peptide Nanofibers

Farsheed, A. C.; Zevallos-Delgado, C.; Yu, L. T.; Saeidifard, S.; Swain, J. W. R.; Makhoul, J. T.; Thomas, A. J.; Cole, C. C.; Garcia Huitron, E.; Grande-Allen, K. J.; Singh, M.; Larin, K. V.; Hartgerink, J. D.

10.1101/2024.02.02.578651 — bioengineering — Posted on 2024-02-04

4119 Focused Ultrasound Blood-Brain Barrier Opening Arrests the Growth and Formation of Cerebral Cavernous Malformations

Fisher, D. G.; Sharifi, K. A.; Shah, I. M.; Gorick, C. M.; Breza, V. R.; Debski, A. C.; Hoch, M.; Cruz, T.; Samuels, J. D.; Sheehan, J.; Schlesinger, D.; Moore, D.; Lukens, J. R.; Tvrdik, P.; Miller, G. W.; Price, R. J.

10.1101/2024.01.31.577810 — bioengineering — Posted on 2024-02-04

4120 Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents

Stockwell, S. R.; Scott, D. E.; Fischer, G.; Guarino, E.; Rooney, T. P. C.; Fang, T.-S.; Moschetti, T.; Srinivasan, R.; Alza, E.; Asteian, A.; Dagostin, C.; Alcaide, A.; Rocaboy, M.; Blaszczyk, B.; Higueruelo, A.; Wang, X.; Rossmann, M.; Perrior, T. R.; Blundell, T. L.; Spring, D. R.; McKenzie, G.; Abell, C.; Skidmore, J.; Venkitaraman, A. R.; Hyvönen, M.

10.1101/2023.03.22.533679 — biochemistry — Posted on 2024-02-04

4121 DNA-dependent phase separation by human SSB2 (NABP1/OBFC2A) protein points to adaptations to eukaryotic genome repair processes

Kovacs, Z. J.; Harami, G. M.; Palinkas, J.; Kuljanishvili, N.; Hegedüs, J.; Harami-Papp, H.; Mahmudova, L.; Khamisi, L.; Szakacs, G.; Kovacs, M.

10.1101/2023.09.15.557979 — biochemistry — Posted on 2024-02-04

4122 Functional Analysis of the Zinc Finger Modules of the S. cerevisiae Splicing Factor Luc7

Carrocci, T. J.; DeMario, S. M.; He, K.; Zeps, N. J.; Harkner, C.; CHANFREAU, G. F.; Hoskins, A.

10.1101/2024.02.04.578419 — biochemistry — Posted on 2024-02-04

4123 Profiling multi-body interactions of BCL2 with single-molecule co-immunoprecipitation reveals the molecular mechanism of ABT-199 resistance

Chun, C.; Yoon, T.-Y.

10.1101/2024.02.04.578783 — biochemistry — Posted on 2024-02-04

4124 Chronic noise increases fitness of a freshwater zooplankton

Prosnier, L.; Rojas, E.; Valero, O.; Medoc, V.

10.1101/2022.11.19.517212 — ecology — Posted on 2024-02-04

4125 Characterisation of behaviours relevant to apathy syndrome in the aged male rat

Jackson, M. G.; Lightman, S. L.; Robinson, E. S. J.

10.1101/2024.02.02.578556 — animal behavior and cognition — Posted on 2024-02-04

4126 Bundle Analytics based Data Harmonization for Multi-Site Diffusion MRI Tractometry

Chandio, B. Q.; Villalon-Reina, J. E.; Nir, T. M.; Thomopoulos, S. I.; Feng, Y. W.; Benavidez, S.; Jahanshad, N.; Harezlak, J.; Garyfallidis, E.; Thompson, P. M.

10.1101/2024.02.03.578764 — neuroscience — Posted on 2024-02-04

4127 Limb, not touch location, is coded in 3D space

Heed, T.; Burbach, J.; Roedenbeck, N.; Habets, B.; Fuchs, X.

10.1101/2024.02.01.578364 — neuroscience — Posted on 2024-02-04

4128 Prefrontal cortex temporally multiplexes slow and fast dynamics in value learning and memory

Hashemirad, S. R.; Abbaszadeh, M.; Ghazizadeh, A.

10.1101/2024.02.02.578632 — neuroscience — Posted on 2024-02-04

4129 Multiple Loci for Foveolar Vision in Macaque Monkey

Qian, M.; Wang, J.; Gao, Y.; Chen, M.; Liu, Y.; Zhou, D.; Lv, H.; Zhang, X.; Hu, J.; Roe, A. W.

10.1101/2024.02.01.578387 — neuroscience — Posted on 2024-02-04

4130 Excitation/Inhibition balance relates to cognitive function and gene expression in Temporal Lobe Epilepsy: an hdEEG assessment with aperiodic exponent

Duma, G. M.; Cuozzo, S.; Wilson, L. E.; Danieli, A.; Bonanni, P.; Pellegrino, G.

10.1101/2024.02.01.578441 — neuroscience — Posted on 2024-02-04

4131 Neonatal Amygdala Mean Diffusivity: A Potential Predictor of Emotional Face Perception

Hashempour, N.; Tuulari, J. J.; Merisaari, H.; Lewis, J. D.; Häikiö, T.; Scheinin, N. M.; Nolvi, S.; Korja, R.; Karlsson, L.; Karlsson, H.; Kataja, E.-L.

10.1101/2024.02.04.578788 — neuroscience — Posted on 2024-02-04

4132 Automated neuropil segmentation of fluorescent images for Drosophila brains

Hsu, K.-Y.; Shih, C.-T.; Chen, N.-Y.; Lo, C.-C.

10.1101/2024.02.03.578770 — neuroscience — Posted on 2024-02-04

4133 Disrupted mitochondrial response to nutrients is a presymptomatic event in the cortex of the APPSAA knock-in mouse model of Alzheimer disease

Norambuena, A.; Sagar, V. K.; Wang, Z.; Raut, P.; Feng, Z.; Wallrabe, H.; Pardo, E.; Kim, T.; Alam, S. R.; Hu, S.; Periasamy, A.; Bloom, G. S.

10.1101/2024.02.02.578668 — neuroscience — Posted on 2024-02-04

4134 Altered nuclear envelope homeostasis is a key pathogenic event in C9ORF72-linked ALS/FTD

Sirtori, R.; Gregoire, M. J.; Collins, A.; Santangelo, S.; Chatragadda, B.; Cullen, R.; Ratti, A.; Fallini, C.

10.1101/2024.02.01.578318 — neuroscience — Posted on 2024-02-04

4135 Investigation of the Relationship Between Calpain and HMGB1/TLR4/NF-KB Signaling Pathway in Multiple Sclerosis and Other Demyelinating Diseases

Uluc, F.; Bozat, B. G.; Karabork, S.; Aydin Turkoglu, S.; Kayis, S. A.

10.1101/2024.02.02.578379 — neuroscience — Posted on 2024-02-04

4136 The Recurrent Temporal Restricted Boltzmann Machine Captures Neural Assembly Dynamics in Whole-brain Activity

Quiroz Monnens, S.; Peters, C.; Hesselink, L. W.; Smeets, K.; Englitz, B.

10.1101/2024.02.02.578570 — neuroscience — Posted on 2024-02-04

4137 Large-Scale Functional Connectome Fingerprinting for Generalization and Transfer Learning in Neuroimaging

Ogg, M.; Kitchell, L.

10.1101/2024.02.02.578642 — neuroscience — Posted on 2024-02-04

4138 Changes in Gait Asymmetry May Be Caused by Adaptation of Spinal Reflexes

Refy, O.; Mo, O.; Hsu, J.; Weber, D. J.; Geyer, H.

10.1101/2024.02.04.578817 — neuroscience — Posted on 2024-02-04

4139 Spatial domain detection using contrastive self-supervised learning for spatial multi-omics technologies

Yao, J.; Yu, J.; Caffo, B.; Page, S. C.; Martinowich, K.; Hicks, S. C.

10.1101/2024.02.02.578662 — bioinformatics — Posted on 2024-02-04

4140 Chronic IL-1-induced DNA double-strand break response in hippocampal neurons drives cognitive deficits

Belloy, M.; Schmitt, B. A.; Marty, F. H.; Paut, C.; Bassot-Parra, E.; Aida, A.; Alis, M.; Ecalard, R.; Boursereau, R.; Gonzalez-Dunia, D.; Blanchard, N.; Suberbielle, E.

10.1101/2024.02.03.578747 — animal behavior and cognition — Posted on 2024-02-04

4141 Inhibition of V1a-like receptors disrupts male-male affiliative relationships formed by triadic cohabitation inlarge-billed crows

Seguchi, A.; Izawa, E.-I.

10.1101/2024.02.01.578519 — animal behavior and cognition — Posted on 2024-02-04

4142 Human-like dissociations between confidence and accuracy in convolutional neural networks

Shekhar, M.; Rahnev, D.

10.1101/2024.02.01.578187 — animal behavior and cognition — Posted on 2024-02-04

4143 HvNotch coordinates two independent pattern forming systems during head regeneration in Hydra by supporting a lateral inhibition process restricting the tentacle system

Steichele, M.; Sauermann, L.; Pan, Q.; Moneer, J.; de la Porte, A.; Hess, M.; Mercker, M.; Strube, C.; Jenewein, M.; Boettger, A.

10.1101/2024.02.02.578611 — developmental biology — Posted on 2024-02-04

4144 Suppression of ERK signalling promotes pluripotent epiblast in the human blastocyst

Simon, C. S.; McCarthy, A.; Woods, L.; Staneva, D.; Huang, Q.; Linneberg-Agerholm, M.; Faulkner, A.; Papathanasiou, A.; Elder, K.; Snell, P.; Christie, L.; Garcia, P.; Shaikly, V.; Taranissi, M.; Choudhary, M.; Herbert, M.; Brickman, J. M.; Niakan, K. K.

10.1101/2024.02.01.578414 — developmental biology — Posted on 2024-02-04

4145 Direct modulation of TRPM8 ion channels by rapamycin and analog macrolide immunosuppressants

Toth, B. I.; Bazeli, B.; Janssens, A.; Lisztes, E.; Racsko, M.; Kelemen, B.; Herczeg, M.; Nagy, T. M.; E. Köver, K.; Mitra, A.; Borics, A.; Biro, T.; Voets, T.

10.1101/2024.02.01.578392 — neuroscience — Posted on 2024-02-04

4146 Circadian regulation of endoplasmic reticulum calcium response in mouse cultured astrocytes

Ryu, J. E.; Shim, K.-W.; Roh, H. W.; Park, M.; Lee, J.-H.; Kim, E. Y.

10.1101/2024.02.02.578616 — neuroscience — Posted on 2024-02-04

4147 Rapid Invisible Frequency Tagging (RIFT) in a novel setup with EEG

Arora, K.; Gayet, S.; Kenemans, J. L.; Van der Stigchel, S.; Chota, S.

10.1101/2024.02.01.578462 — neuroscience — Posted on 2024-02-04

4148 Aperiodic and Hurst EEG exponents across early human brain development: a systematic review

Stanyard, R. A.; Mason, D.; Ellis, C.; Dickson, H.; Short, R.; Batalle, D.; Arichi, T.

10.1101/2024.02.02.578622 — neuroscience — Posted on 2024-02-04

4149 Preparatory activity during visual search reflects attention-guiding objects rather than search targets

Lerebourg, M.; de Lange, F. P.; Peelen, M. V.

10.1101/2024.02.02.578555 — neuroscience — Posted on 2024-02-04

4150 Distractor suppression operates exclusively in retinotopic coordinates

Ilksoy, Y. A.; van Moorselaar, D.; Wang, B.; Los, S. A.; Theeuwes, J.

10.1101/2024.02.01.578407 — neuroscience — Posted on 2024-02-04

4151 Neural substrates underlying the expectation of rewards resulting from effortful exertion

Kim, A.; Chib, V. S.

10.1101/2024.02.01.578411 — neuroscience — Posted on 2024-02-04

4152 Cell lipotypes localization in brain by mass spectrometry imaging

Martinez-Gardeazabal, J.; Moreno-Rodriguez, M.; Llorente-Ovejero, A.; Gonzalez de San Roman, E.; Lombardero, L.; Bengoetxea de Tena, I.; Sustacha, J.; Matute, C.; Manuel, I.; Bonifazi, P.; Rodriguez-Puertas, R.

10.1101/2024.02.02.578599 — neuroscience — Posted on 2024-02-04

4153 Expression of novel androgen receptors in three GnRH neuron subtypes in the cichlid brain

Dussenne, M.; Alward, B. A.

10.1101/2024.02.02.578641 — neuroscience — Posted on 2024-02-04

4154 Solaris: a panel of bright and sensitive hybrid voltage indicators for imaging membrane potential in cultured neurons

Yang, J.; Zhu, S.; Yang, L.; Peng, L.; Han, Y.; Hayward, R. F.; Park, P.; Hu, D.; Cohen, A. E.; Zou, P.

10.1101/2024.02.02.578569 — neuroscience — Posted on 2024-02-04

4155 Aging hastens locomotor decline in PINK1 knockout rats in association with decreased nigral, but not striatal, dopamine and tyrosine hydroxylase expression

Soto, I.; McManus, R.; Navarrete-Barahona, W.; Kasanga, E. A.; Doshier, K.; Nejtek, V. A.; Salvatore, M. F.

10.1101/2024.02.01.578317 — neuroscience — Posted on 2024-02-04

4156 Identifying the factors governing internal state switches during nonstationary sensory decision-making

Mohammadi, Z.; Pillow, J. W.; Ashwood, Z. C.; International Brain Laboratory,

10.1101/2024.02.02.578482 — neuroscience — Posted on 2024-02-04

4157 TMEM63B functions as a mammalian thirst receptor

Zou, W.; Chen, X.; Ruan, J.; Deng, S.; Zhan, W.; Wang, J.; Liu, Z.; Yan, Z.

10.1101/2024.02.01.578339 — neuroscience — Posted on 2024-02-04

4158 Task-irrelevant phase but not contrast variability unlocks generalization in visual perceptual learning

Akkoyunlu, B.; Schwiedrzik, C. M.

10.1101/2024.02.01.578442 — neuroscience — Posted on 2024-02-04

4159 The timescale and functional form of context-dependence during human value-learning

Tohidi-Moghaddam, M.; Tsetsos, K.

10.1101/2024.02.01.578398 — neuroscience — Posted on 2024-02-04

4160 Optogenetic Locus Coeruleus Stimulation Improves Pupil Size Tracking of Cortical State

Weiss, E.; Liu, Y.; Wang, Q.

10.1101/2024.02.02.578675 — neuroscience — Posted on 2024-02-04

4161 Elevated Activity in Left Homologous Music Circuits is Maladaptive for Music Perception but Mediated by Decoupled Structure and Function

Wang, Y.; Jin, Z.; Huyang, S.; Lian, Q.; Wu, D.

10.1101/2024.02.04.578219 — neuroscience — Posted on 2024-02-04

4162 μSim: A goal-driven framework for elucidating the neural control of movement through musculoskeletal modeling

Almani, M. N.; Lazzari, J.; Chacon, A.; Saxena, S.

10.1101/2024.02.02.578628 — neuroscience — Posted on 2024-02-04

4163 Psilocybin-enhanced fear extinction linked to bidirectional modulation of cortical ensembles

Rogers, S. A.; Heller, E. A.; Corder, G.

10.1101/2024.02.04.578811 — neuroscience — Posted on 2024-02-04

4164 Attractor-like circuits improve visual decoding and behavior in zebrafish

Privat, M.; Hansen, E.; Pietri, T.; Marachlian, E.; Uribe, A.; Duchemin, A.; Candat, v.; Nourin, S.; Sumbre, G.

10.1101/2024.02.03.578596 — neuroscience — Posted on 2024-02-04

4165 Transcriptional programs mediating neuronal toxicity and altered glial-neuronal signaling in a Drosophila knock-in tauopathy model

Bukhari, H.; Nithianandam, V.; Battaglia, R.; Cicalo, A.; Sarkar, S.; Comjean, A.; Hu, Y.; Leventhal, M.; Dong, X.; Feany, M.

10.1101/2024.02.02.578624 — neuroscience — Posted on 2024-02-04

4166 Characterization of ribosome stalling and no-go mRNA decay stimulated by the Fragile X protein, FMRP

Scarpitti, M. R.; Pastore, B.; Tang, W.; Kearse, M. G.

10.1101/2024.02.02.577121 — biochemistry — Posted on 2024-02-04

4167 Ready, set, yellow! Color Preference of Indian Free-ranging Dogs

Roy, A.; Lahiri, A.; Nandi, S.; Manchalwar, A.; S, S.; Bhadra, A.

10.1101/2024.02.01.578151 — animal behavior and cognition — Posted on 2024-02-04

4168 Pharmacological Enhancement of Adult Hippocampal Neurogenesis Improves Behavioral Pattern Separation in Young and Aged Mice

Chang, W.-l.; Tegang, K.; Samuels, B. A.; Saxe, M.; Wichmann, J.; David, D. J.; David, I. M.; Augustin, A.; Fischer, H.; Golling, S.; Lamerz, J.; Roth, D.; Graf, M.; Zoffmann, S.; Santarelli, L.; Jagasia, R.; Hen, R.

10.1101/2024.02.01.578406 — animal behavior and cognition — Posted on 2024-02-04

4169 Jag1 represses Notch activation in lateral supporting cells and inhibits an outer hair cell fate in the medial compartment of the developing cochlea

de Haan, S.; Corbat, A. A.; Cederroth, C. R.; Autrum, L. G.; Hankeova, S.; Driver, E. C.; Canlon, B.; Kelley, M. W.; Andersson, E. R.

10.1101/2024.02.02.577075 — developmental biology — Posted on 2024-02-04

4170 Energy scarcity and impaired mitochondrial translation induce perinuclear stress granule clustering

Fernadez-Pelayo, U.; Munoz-Oreja, M.; Villar-Fernandez, M.; Lopez de Arbina, A.; Aiestaran- Zelaia, I.; Sanchez-Guisado, M. J.; Pantic, B.; Elicegui, A.; Zufiria, M.; Iruzubieta, P.; Sagartzazu-Aizpurua, M.; Aizpurua, J. M.; Gegg, M.; Alonso-Martin, S.; Ruiz-Cabello, J.; Gil Bea, F.; Spinazzola, A.; Lopez de Munain, A.; Holt, I.

10.1101/2024.02.01.578399 — cell biology — Posted on 2024-02-04

4171 Npbwr1 signaling mediates fast antidepressant action

Stein, G.; Aly, J. S.; Lange, L.; Manzolillo, A.; Riege, K.; Brancato, A.; Huebner, C. A.; Turecki, G.; Hoffmann, S.; Engmann, O.

10.1101/2024.02.02.578166 — neuroscience — Posted on 2024-02-04

4172 Identifying A Neural Signature That Predicts Self-Focus

Geisler, D. J.; Meyer, M.

10.1101/2024.02.01.578262 — neuroscience — Posted on 2024-02-04

4173 Pia-FLOW: Deciphering hemodynamic maps of the pial vascular connectome and its response to arterial occlusion

Glueck, C.; Zhou, Q.; Droux, J.; Chen, Z.; Glandorf, L.; Wegener, S.; Razansky, D.; Weber, B.; EL AMKI, M.

10.1101/2024.02.02.577749 — neuroscience — Posted on 2024-02-04

4174 Representational dissimilarity component analysis (ReDisCA)

Ossadtchi, A.; Semenkov, I.; Zhuravleva, A.; Serikov, O.; Voloshina, E.

10.1101/2024.02.01.578343 — neuroscience — Posted on 2024-02-04

4175 Deep learning-based location decoding reveals that across-day representational drift is better predicted by rewarded experience than time

Freud, K. M.; Lepora, N.; Jones, M. W.; O'Donnell, C.

10.1101/2024.02.01.578423 — neuroscience — Posted on 2024-02-04

4176 NeuroTri2-VISDOT: An open-access tool to harness the power of second trimester human single cell data to inform models of Mendelian neurodevelopmental disorders

Clark, K. J.; Lubin, E. E.; Gonzalez, E. M.; Sangree, A. K.; Layo-Carris, D. E.; Durham, E. L.; Ahrens-Nicklas, R. C.; Nomakuchi, T. T.; Bhoj, E. J. K.

10.1101/2024.02.01.578438 — genetics — Posted on 2024-02-04

4177 Single-molecule chromatin configurations link transcription factor binding to expression in human cells

Doughty, B. R.; Hinks, M. M.; Schaepe, J. M.; Marinov, G. K.; Thurm, A. R.; Rios-Martinez, C.; Parks, B. E.; Tan, Y.; Marklund, E.; Dubocanin, D.; Bintu, L.; Greenleaf, W. J.

10.1101/2024.02.02.578660 — molecular biology — Posted on 2024-02-04

4178 Dynamic regulation of CeA gene expression during acute and protracted abstinence from chronic binge drinking of male and female C57BL/6J mice.

Mendez, H. G.; Neira, S.; Flanigan, M. E.; Haun, H. L.; Boyt, K.; Thiele, T.; Kash, T. L.

10.1101/2024.02.02.578650 — neuroscience — Posted on 2024-02-04

4179 Counter-regulation of RNA stability by UPF1 and TDP43

Gomez, N.; Hsieh, C.; Li, X.; Dykstra, M.; Waksmacki, J.; Altheim, C.; Bechar, Y.; Klim, J.; Zaepful, B.; Rothstein, J.; Tank, E. M.; Barmada, S. J.

10.1101/2024.01.31.578310 — neuroscience — Posted on 2024-02-04

4180 Sex Differences in the Brain's White Matter Microstructure during Development assessed using Advanced Diffusion MRI Models

Benavidez, S. M.; Abaryan, Z.; Kim, G. S.; Laltoo, E.; McCracken, J. T.; Thompson, P. M.; Lawrence, K. E.

10.1101/2024.02.02.578712 — neuroscience — Posted on 2024-02-04

4181 Cactus: a user-friendly and reproducible ATAC-Seq and mRNA-Seq analysis pipeline for data preprocessing, differential analysis, and enrichment analysis

Salignon, J.; Millan-Arino, L.; Garcia, M.; Riedel, C. G.

10.1101/2023.05.11.540110 — bioinformatics — Posted on 2024-02-04

4182 Deep Learning Prediction of Glycopeptide Tandem Mass Spectra Powers Glycoproteomics

Zong, Y.; Wang, Y.; Qiu, X.; Huang, X.; Qiao, L.

10.1101/2024.02.03.575604 — bioinformatics — Posted on 2024-02-04

4183 A rapid approach for sex assignment by RAD-seq using a reference genome

Peralta, D. M.; Tunez, J. I.; Rodriguez Cruz, U. E.; Ceballos, S. G.

10.1101/2023.01.30.526394 — bioinformatics — Posted on 2024-02-04

4184 Does the seed fall far from the tree? Weak fine scale genetic structure in a continuous Scots pine population

Niskanen, A. K.; Kujala, S. T.; Karkkainen, K.; Savolainen, O.; Pyhajarvi, T.

10.1101/2023.06.16.545344 — evolutionary biology — Posted on 2024-02-04

4185 Hippocampal sequences span experience relative to rewards

Sosa, M.; Plitt, M. H.; Giocomo, L. M.

10.1101/2023.12.27.573490 — neuroscience — Posted on 2024-02-04

4186 THE WIP6 TRANSCRIPTION FACTOR TOO MANY LATERALS SPECIFIES VEIN TYPE IN C4 AND C3 GRASS LEAVES

Vlad, D.; Zaidem, M.; Perico, C.; Sedelnikova, O.; Bhattacharya, S.; Langdale, J. A.

10.1101/2023.12.20.572592 — plant biology — Posted on 2024-02-04

4187 Enhancing mitochondrial pyruvate metabolism ameliorates myocardial ischemic reperfusion injury.

Visker, J. R.; Cluntun, A. A.; Velasco-Silva, J. N.; Eberhardt, D. R.; Shankar, T. S.; Hamouche, R.; Ling, J.; Kwak, H.; Hillas, Y.; Aist, I.; Tseliou, E.; Navankasattusas, S.; Chaudhuri, D.; Ducker, G. S.; Drakos, S. G.; Rutter, J.

10.1101/2024.02.01.577463 — physiology — Posted on 2024-02-04

4188 Multicolor fluorescence microscopy for surgical guidance using a chip-scale imager with a low-NA fiber optic plate and a multi-bandpass interference filter

Roschelle, M. L.; Rabbani, R.; Papageorgiou, E.; Zhang, H.; Cooperberg, M.; Stohr, B. A.; Niknejad, A.; Anwar, M.

10.1101/2023.10.16.562247 — cancer biology — Posted on 2024-02-04

4189 Identification of anisotropy in chromosome dynamics by principal component analysis using integrated spatial genomics

Nara, T.; Takahashi, H.; Awazu, A.; Kikuchi, Y.

10.1101/2024.01.27.577362 — bioinformatics — Posted on 2024-02-04

4190 Primary auditory cortex is necessary for the acquisition and expression of categorical behavior

Krall, R. F.; Chambers, C. N.; Arnold, M. P.; Brougher, L. I.; Chen, J.; Deshmukh, R.; King, H. B.; Morford, H. J.; Wiemann, J. M.; Williamson, R. S.

10.1101/2024.02.02.578700 — neuroscience — Posted on 2024-02-04

4191 Semi-synthetic glycoconjugate vaccine candidate against Cryptococcus neoformans

Crawford, C. J.; Liporagi-Lopes, L.; Coelho, C.; Santos Junior, S. R.; Nicola, A. M.; Wear, M. P.; Oscarson, S.; Casadevall, A.

10.1101/2024.02.02.578725 — immunology — Posted on 2024-02-03

4192 Unraveling the impact of congenital deafness on individual brain organization

Amaral, L.; Wang, X.; Bi, Y.; Striem-Amit, E.

10.1101/2024.02.02.578685 — neuroscience — Posted on 2024-02-04

4193 Functional Connectivity Differences in Distinct Dentato-Cortical Networks in Alzheimers Disease and Mild Cognitive Impairment

Herrejon, I.; Jackson, T. B.; Hicks, T. H.; Bernard, J. A.

10.1101/2024.02.02.578249 — neuroscience — Posted on 2024-02-04

4194 Tryptanthrin Analogs Substoichiometrically Inhibit Seeded and Unseeded Tau4RD Aggregation

James, E. I.; Baggett, D. W.; Chang, E.; Schachter, J.; Nixey, T.; Choi, K.; Guttman, M.; Nath, A.

10.1101/2024.02.02.578649 — biochemistry — Posted on 2024-02-03

4195 Triplex real-time PCR ZKIR-T assay for simultaneous detection of the Klebsiella pneumoniae species complex and identification of K. pneumoniae sensu stricto

Ligowska-Marzeta, M.; Barbier, E.; Rodrigues, C.; Piveteau, P.; Schroeder Hansen, D.; Hartmann, A.; Moller-Nielsen, E.; Brisse, S.

10.1101/2024.02.02.578617 — microbiology — Posted on 2024-02-03

4196 Characterization and functional analysis of Toxoplasma Golgi-associated proteins identified by proximity labelling

Pasquarelli, R. R.; Quan, J. J.; Yang, V.; Britton, T. A.; Sha, J.; Wohlschlegel, J. A.; Bradley, P. J.

10.1101/2024.02.02.578703 — microbiology — Posted on 2024-02-03

4197 Comprehensive analysis of the microbial consortium in the culture of flagellate Monocercomonoides exilis

Jimenez-Gonzalez, A.; Treitli, S. C.; Pena-Diaz, P.; Janovska, A.; Benes, V.; Zacek, P.; Hampl, V.

10.1101/2024.02.02.578639 — microbiology — Posted on 2024-02-03

4198 Caspase-8 activity mediates TNFα production and restricts Coxiella burnetii replication during murine macrophage infection

Osbron, C. A.; Lawson, C.; Hanna, N.; Koehler, H.; Goodman, A. G.

10.1101/2024.02.02.578698 — microbiology — Posted on 2024-02-03

4199 ComI inhibits transformation in Bacillus subtilis by selectively killing competent cells

Smith, D. R.; Kearns, D. B.; Burton, B. M.

10.1101/2024.02.02.578676 — microbiology — Posted on 2024-02-03

4200 PackDock: a Diffusion Based Side Chain Packing Model for Flexible Protein-Ligand Docking

Zhang, R.; Jiang, X.; Cao, D.; Yu, J.; Chen, M.; Fan, Z.; Kong, X.; Xiong, J.; Zhang, Z.; Zhang, W.; Ni, S.; Wang, Y.; Gao, S.; Zheng, M.

10.1101/2024.01.31.578200 — bioinformatics — Posted on 2024-02-03

4201 Targeted Degradation of METTL3 Against Acute Myeloid Leukemia and Gastric Cancer.

Hwang, K.; Bae, J.; Jhe, Y.-L.; Kim, J.; Cheong, J.-H.; Sim, T.

10.1101/2024.02.02.578521 — biochemistry — Posted on 2024-02-03

4202 Conserved Pseudouridines in Helix 69 of the Ribosome are Important for Ribosome Dynamics in Translation

Jin, H.; Chen, X.

10.1101/2024.02.02.578723 — biochemistry — Posted on 2024-02-03

4203 Structural insights into agonist binding and activation of succinate receptor 1

Liu, A.; Liu, Y.; Zhang, W.; Ye, R.

10.1101/2024.02.03.578529 — biochemistry — Posted on 2024-02-03

4204 Transcriptional responses to priority effects in nectar yeast

Chappell, C. R.; Goddard, P.; Golden, L.; Hernandez, J.; Ortiz Chavez, D.; Hossine, M.; Herrera Paredes, S.; Fukami, T.; Dhami, M. K.

10.1101/2024.01.30.578081 — ecology — Posted on 2024-02-03

4205 Genetic and phylogenetic features of the repetitive ITS copies in the Hirsutella sinensis genome and the genomically independent AT-biased Ophiocordyceps sinensis genotypes

Li, X.-Z.; Li, Y.-l.; Wang, Y.-N.; Zhu, J.-S.

10.1101/2022.12.09.519819 — molecular biology — Posted on 2024-02-03

4206 Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses

Gilbert-girard, S.; Piret, J.; Carbonneau, J.; Henaut, M.; Goyette, N.; Boivin, G.

10.1101/2024.02.02.578538 — microbiology — Posted on 2024-02-03

4207 Lipidomics of homeoviscous adaptation to low temperatures in Staphylococcus aureus utilizing exogenous straight-chain unsaturated fatty acids over biosynthesized endogenous branched-chain fatty acids

Barbarek, S. C.; Shah, R.; Paul, S.; Alvarado, G.; Appala, K.; Henderson, E. C.; Strandquist, E. T.; Pokorny, A.; Singh, V. K.; Gatto, C.; Dahl, J.-U.; Hines, K. M.; Wilkinson, B. J.

10.1101/2024.02.02.578686 — microbiology — Posted on 2024-02-03

4208 P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis

Li, Z.; Barnaby, R.; Nymon, A.; Roche, C.; Koeppen, K.; Ashare, A.; Hogan, D.; Gerber, S. A.; Taatjes, D.; Hampton, T. H.; Stanton, B.

10.1101/2024.02.03.578737 — microbiology — Posted on 2024-02-03

4209 Multiple Small RNAs Modulate Rho-Dependent Termination in the Cyclopropane Fatty Acid Synthase mRNA 5' Untranslated Region

Farley, K. R.; Bianco, C. M.; Vanderpool, C. K.

10.1101/2024.02.02.578684 — microbiology — Posted on 2024-02-03

4210 Niche exclusion of a lung pathogen in mice with designed probiotic communities

Hern, K. E.; Phillips, A. M. E.; Mageeney, C. M.; Williams, K. P.; Sinha, A.; Carlson, H. K.; Collette, N. M.; Branda, S. S.; Arkin, A. P.

10.1101/2024.02.02.578711 — microbiology — Posted on 2024-02-03

4211 PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in hepatocytes.

Sarkar, B.; Singh, J.; Yadav, M.; Sharma, P.; Sharma, R. D.; Singh, S.; Chandramouli, A.; Kumar, A.; Kamat, S. S.; Ghorpade, D. S.; Mohanty, D.; Kumar, D.; Gokhale, R. S.

10.1101/2024.02.02.578554 — microbiology — Posted on 2024-02-03

4212 A nox2 / cybb zebrafish mutant with defective neutrophil ROS production displays normal initial neutrophil recruitment to sterile tail injuries

Lieschke, G. J.; Isiaku, A. I.; Zhang, Z.; Pazhakh, V.

10.1101/2024.02.02.578645 — immunology — Posted on 2024-02-03

4213 Iron deficiency causes aspartate-sensitive metabolic and proliferative dysfunction in CD8+ T cells

Teh, M. R.; Gudgeon, N.; Frost, J. N.; Sinclair, L. V.; Smith, A. L.; Millington, C. L.; Kronsteiner, B.; Roberts, J.; Marzullo, B. P.; Preston, A. E.; Rehwinkel, J.; Milne, T. A.; Tennant, D. A.; Dunachie, S. J.; Armitage, A. E.; Dimeloe, S. K.; Drakesmith, H.

10.1101/2024.02.01.578381 — immunology — Posted on 2024-02-03

4214 Implicit motor adaptation patterns in a redundant motor task manipulating a stick with both hands

Kobayashi, T.; Nozaki, D.

10.1101/2023.06.13.544873 — neuroscience — Posted on 2024-02-03

4215 Different fluorescent labels report distinct components of spHCN channel voltage sensor movement

Wojciechowski, M. N.; McKenzie, C.; Hung, A.; Kuanyshbek, A.; Soh, M. S.; Reid, C. A.; Forster, I. C.

10.1101/2024.01.23.576936 — biophysics — Posted on 2024-02-03

4216 The co-receptor Tspan12 directly captures Norrin to promote ligand-specific β-catenin signaling

Bruguera, E. S.; Mahoney, J. P.; Weis, W. I.

10.1101/2024.02.03.578714 — biochemistry — Posted on 2024-02-03

4217 Novel spirocyclic dimer, SpiD3, targets chronic lymphocytic leukemia survival pathways with potent preclinical effects

Eiken, A.; Smith, A. L.; Skupa, S. A.; Schmitz, E.; Rana, S.; Singh, S.; Kumar, S.; Mallareddy, J. R.; de Cubas, A. A.; Krishna, A.; Kalluchi, A.; Rowley, J.; D'Angelo, C. R.; Lunning, M. A.; Bociek, R. G.; Vose, J. M.; Natarajan, A.; ElGamal, D.

10.1101/2024.01.31.578283 — cancer biology — Posted on 2024-02-03

4218 Grayscale 4D Biomaterial Customization at High Resolution and Scale

Batalov, I.; Filteau, J. R.; Francis, R. M.; Jaindl, G.; Orr, L.; Rapp, T. L.; Yang, S.; Filteau, J. A.; Xie, W.; Bretherton, R. C.; Glaser, A. K.; Liu, J. T. C.; Stevens, K. R.; DeForest, C. A.

10.1101/2024.01.31.578280 — bioengineering — Posted on 2024-02-03

4219 Novel Alphaproteobacteria transcribe genes for nitric oxide transformation at high levels in a marine oxygen deficient zone

Elbon, C. E.; Stewart, F. J.; Glass, J. B.

10.1101/2023.11.21.568154 — microbiology — Posted on 2024-02-03

4220 Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

Furtado, K. L.; Plott, L. M.; Markovetz, M. R.; Powers, D. A.; Wang, H.; Hill, D. B.; Papin, J. A.; Allbritton, N. L.; Tamayo, R.

10.1101/2024.02.01.578425 — microbiology — Posted on 2024-02-03

4221 Retrograde adenosine/A2A receptor signaling facilitates excitatory synaptic transmission and seizures

Nasrallah, K.; Berthoux, C.; Hashimotodani, Y.; Chavez, A. E.; Gulfo, M.; Lujan, R.; Castillo, P. E.

10.1101/2021.10.07.463512 — neuroscience — Posted on 2024-02-03

4222 Targeting neuroinflammation by pharmacologic down-regulation of inflammatory pathways is neuroprotective in protein misfolding disorders.

Risen, S. J.; Boland, S.; Sharma, S.; Weismann, G.; Shirley, P.; Latham, A. S.; Hay, A. J. D.; Gilberto, V. S.; Hines, A. D.; Brindley, S.; Brown, J. M.; McGrath, S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.

10.1101/2022.09.26.509513 — neuroscience — Posted on 2024-02-03

4223 A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria (RDoC) Framework

Quah, S. K. L.; Jo, B.; Geniesse, C.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Saggar, M.

10.1101/2024.01.31.577486 — neuroscience — Posted on 2024-02-03

4224 Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues

Forjaz, A.; Vaz, E.; Romero, V. M.; Joshi, S.; Braxton, A. M.; Jiang, A. C.; Fujikura, K.; Cornish, T.; Hong, S.-M.; Hruban, R. H.; Wu, P.-H.; Wood, L. D.; Kiemen, A. L.; Wirtz, D.

10.1101/2023.12.04.569986 — cancer biology — Posted on 2024-02-03

4225 A Genetic Screen for regulators of CNS morphology in Drosophila

Lacin, H.; Zhu, Y.; DiPaola, J.; Wilson, B. A.; Zhu, Y.; Skeath, J. B.

10.1101/2024.01.09.574922 — genetics — Posted on 2024-02-03

4226 Executioner caspase is proximal to Fasciclin 3 which facilitates non-lethal activation in Drosophila olfactory receptor neurons

Muramoto, M.; Hanawa, N.; Okumura, M.; Chihara, T.; Miura, M.; Shinoda, N.

10.1101/2023.07.20.549821 — molecular biology — Posted on 2024-02-03

4227 Dynamics of the membrane- and cell wall-associated proteome of Arabidopsis thaliana roots in response to uranium stress

Przybyla-Toscano, J.; Chetouhi, C.; Balliaud, T.; ALBAN, C.; Bourguignon, J.; Ravanel, S.

10.1101/2024.02.02.578547 — plant biology — Posted on 2024-02-03

4228 Wheat NAC transcription factor NAC5-1 is a positive regulator of senescence

Evans, C.; Mogg, S. L.; Soraru, C.; Wallington, E.; Coates, J. C.; Borrill, P.

10.1101/2024.02.02.578592 — plant biology — Posted on 2024-02-03

4229 Identification and characterization of a temperature sensitive chlorotic soybean mutant

Hancock, C. N.; Germany, T.; Redd, P.; Timmons, J.; Lipford, J.; Burns, S.; Cervantes-Perez, S. A.; Libault, M.; Shen, W.; An, Y.-q. C.; Kanizay, L.; Yerka, M.; Parrott, W. A.

10.1101/2024.02.02.578604 — plant biology — Posted on 2024-02-03

4230 Tyrosine-sulfated peptide hormone induces flavonol biosynthesis to control elongation and differentiation in Arabidopsis primary root.

Ercoli, M. F.; Shigenaga, A.; Teixeira de Araujo Junior, A.; Jain, R.; Ronald, P.

10.1101/2024.02.02.578681 — plant biology — Posted on 2024-02-03

4231 Grapevine cell response to carbon deficiency requires transcriptome and methylome reprogramming

Berger, M. M. J.; Garcia, V.; Lacrampe, N.; Rubio, B.; Decros, G.; Petriacq, P.; Flandin, A.; Cassan, C.; Hilbert-Masson, G.; Colombie, S.; Atanassova, R.; Gallusci, P.

10.1101/2024.02.02.578586 — plant biology — Posted on 2024-02-03

4232 The correlation between Rate of Force Development Maximal Strength and Electromyography Variables of Basketball Athletes.

Brandao, H. C. P.; de Andrade, M. M.; Carmo, J. C. d.

10.1101/2024.01.31.578254 — neuroscience — Posted on 2024-02-03

4233 Reducing stomatal density by expression of a synthetic EPF increases leaf intrinsic water use efficiency and reduces plant water use in a C4 crop

Ferguson, J. N.; Schmuker, P.; Dmitrieva, A.; Quach, T.; Zhang, T.; Ge, Z.; Nersesian, N.; Sato, S.; Clemente, T.; Leakey, A.

10.1101/2024.02.01.578512 — plant biology — Posted on 2024-02-03

4234 FoxO factors are essential for maintaining organ homeostasis by acting as stress sensors in airway epithelial cells

Uliczka, K.; Bossen, J. M.; Zissler, U.; Fink, C.; Niu, X.; Pieper, M.; Prange, R. D.; Vock, C.; Wagner, C.; Knop, M.; Abdelsadik, A.; Franzenburg, S.; Bruchhaus, I.; Wegmann, M.; Schmidt-Weber, C. B.; König, P.; Pfefferle, P.; Heine, H.; Roeder, T.

10.1101/2024.01.31.578231 — physiology — Posted on 2024-02-03

4235 Impaired motor-to-sensory transformation mediates auditory hallucinations

Yang, F.; Zhu, H.; Cao, X.; Li, H.; Fang, X.; Yu, L.; Li, S.; Wu, Z.; Li, C.; Zhang, C.; Tian, X.

10.1101/2023.06.10.544451 — neuroscience — Posted on 2024-02-03

4236 The long noncoding RNA lnc-FANCI-2 restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer cells

Liu, H.; Yu, L.; Majerciak, V.; Meyer, T.; Yi, M.; Johnson, P. F.; Cam, M.; Lowy, D. R.; Zheng, Z.-M.

10.1101/2024.02.01.578320 — cancer biology — Posted on 2024-02-03

4237 EpiGePT: a Pretrained Transformer model for epigenomics

Gao, Z.; Liu, Q.; Zeng, W.; Jiang, R.; Wong, W. H.

10.1101/2023.07.15.549134 — genomics — Posted on 2024-02-03

4238 Development of a cell-based DIFF-rGFP assay system for generalized discovery of viral protease Inhibitors

Xiaoyan, W.; Yan, F.; Ruiting, C.; Chenjie, F.; Shuai, W.; Huimin, S.; Shuling, J.; Jiasheng, S.; Beibei, W.

10.1101/2024.02.01.577684 — molecular biology — Posted on 2024-02-03

4239 Taurine pangenome uncovers a segmental duplication upstream of KIT associated with depigmentation in white-headed cattle

Milia, S.; Leonard, A. S.; Mapel, X. M.; Bernal Ulloa, S. M.; Droegemueller, C.; Pausch, H.

10.1101/2024.02.02.578587 — genomics — Posted on 2024-02-02

4240 Dissecting quantitative trait nucleotides by saturation genome editing

Roy, K. R.; Smith, J. D.; Li, S.; Vonesch, S. C.; Nguyen, M.; Burnett, W. T.; Orsley, K. M.; Lee, C.-S.; Haber, J. E.; St.Onge, R. P.; Steinmetz, L. M.

10.1101/2024.02.02.577784 — genetics — Posted on 2024-02-02

4241 Developmental and molecular contributions to contextual fear memory emergence in mice

Lanjewar, A. L.; Levitt, P.; Eagleson, K. L.

10.1101/2023.02.03.527024 — neuroscience — Posted on 2024-02-02

4242 Hexagons all the way down: Grid cells as a conformal isometric map of space

Schoyen, V. S.; Beshkov, K.; Pettersen, M. B.; Hermansen, E.; Holzhausen, K.; Malthe-Sorenssen, A.; Fyhn, M.; Lepperod, M. E.

10.1101/2024.02.02.578585 — neuroscience — Posted on 2024-02-02

4243 A spatial model of autophosphorylation of CaMKII in a glutamatergic spine suggests a network-driven kinetic mechanism for bistable changes in synaptic strength.

Bartol, T. M.; Ordyan, M.; Sejnowski, T. J.; Rangamani, P.; Kennedy, M. B.

10.1101/2024.02.02.578696 — neuroscience — Posted on 2024-02-02

4244 Independent regulation of early trafficking of NMDA receptors by ligand-binding domains of the GluN1 and GluN2A subunits

Netolicky, J.; Zahumenska, P.; Misiachna, A.; Kolcheva, M.; Kucera, T.; Fibigar, J.; Rehakova, K.; Hemelikova, K.; Kortus, S.; Langore, E.; Ladislav, M.; Korabecny, J.; Horak, M.

10.1101/2024.02.02.578575 — neuroscience — Posted on 2024-02-02

4245 Serotonin drives aggression and social behaviours of laboratory mice in a semi-natural environment

Rivalan, M.; Alonso, L.; Mosienko, V.; Bey, P.; Hyde, A.; Bader, M.; Winter, Y.; Alenina, N.

10.1101/2024.02.02.578690 — neuroscience — Posted on 2024-02-02

4246 Investigating the Synergistic Role of GCN2 and HPA Axis in Regulating Integrated Stress Response in the Central Circadian Timing System

Li, Y.; Lu, L.; Levy, J. L.; Anthony, T. G.; Androulakis, I. P.

10.1101/2024.02.01.578301 — systems biology — Posted on 2024-02-02

4247 RNA3DB: a dataset for training and benchmarking deep learning models for RNA structure prediction

Szikszai, M.; Magnus, M.; Sanghi, S.; Kadyan, S.; Bouatta, N.; Rivas, E.

10.1101/2024.01.30.578025 — bioinformatics — Posted on 2024-02-02

4248 Microtubules ensure transport of vegetative nuclei and sperm cells by fine-tuning their home positions

Motomura, K.; Tsuchi, H.; Komojiri, M.; Matsumoto, A.; Sugi, N.; Susaki, D.; Takeda, A.; Kinoshita, T.; Maruyama, D.

10.1101/2024.01.31.578224 — plant biology — Posted on 2024-02-02

4249 The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces

Kellner, A. V.; Hunter, R.; Do, P.; Eggert, J.; Jaffe, M.; Geitgey, D. K.; Lee, M.; Hamilton, J. A. G.; Ross, A. J.; Ank, R. S.; Bender, R. L.; Ma, R.; Porter, C. C.; Dreaden, E. C.; Au-Yeung, B. B.; Haynes, K. A.; Henry, C. J.; Salaita, K.

10.1101/2024.01.31.578101 — bioengineering — Posted on 2024-02-02

4250 A weaponized phage suppresses competitors in historical and modern metapopulations of pathogenic bacteria

Backman, N.; Latorre, S. M.; Symeonidi, E.; Muszynski, A.; Bleak, E.; Eads, L.; Martinez-Koury, P.; Som, S.; hawks, A.; Gloss, A. D.; Belnap, D.; Manuel, A. M.; Deutschbauer, A.; Bergelson, J.; Azadi, P.; Burbano-Roa, H. A.; Karasov, T.

10.1101/2023.04.17.536465 — microbiology — Posted on 2024-02-02

4251 Phylogenetically and structurally diverse reductive dehalogenases link biogeochemical cycles in deep-sea cold seeps

Han, Y.; Peng, Y.; Peng, J.; Cao, L.; Xu, Y.; Yang, Y.; Wu, M.; Zhou, H.; Zhang, C.; Zhang, D.; Wang, M.; Greening, C.; Dong, X.

10.1101/2024.01.23.576788 — microbiology — Posted on 2024-02-02

4252 Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

Yu, H.; Nishio, H.; Barbi, J.; Mitchell-Flack, M.; Vignali, P. D. A.; Zheng, Y.; Lebid, A.; Chang, K.-Y.; Fu, J.; Higgins, M.; Huang, C.-T.; Zhang, X.; Li, Z.; Blosser, L.; Tam, A.; Drake, C. G.; Pardoll, D. M.

10.1101/2024.01.31.578284 — immunology — Posted on 2024-02-02

4253 A systematic analysis of the joint effects of ganglion cells, lagged LGN cells, and intercortical inhibition on spatiotemporal processing and direction selectivity

Larisch, R.; Hamker, F. H.

10.1101/2024.01.31.578157 — neuroscience — Posted on 2024-02-02

4254 Cilia-mediated cerebrospinal fluid flow modulates neuronal and astroglial activity in the zebrafish larval brain.

D'Gama, P. P.; Jeong, I.; Nygard, A. M.; Jamali, A.; Yaksi, E.; Jurisch-Yaksi, N.

10.1101/2024.02.01.578354 — neuroscience — Posted on 2024-02-02

4255 A multiple Arc (mArc) tagging system to uncover the organizational principles of multiple memories

Stackmann, M.; Yelhekar, T. D.; Meng, M.; Sun, X.; Nthumba, J.; Bulthuis, N. E.; Vaughan, N.; Zhu, E.; Lin, Y.; Denny, C. A.

10.1101/2024.02.01.578410 — neuroscience — Posted on 2024-02-02

4256 Generating information-dense promoter sequences with optimal string packing

Andreani, V.; South, E.; Dunlop, M.

10.1101/2023.11.01.565124 — systems biology — Posted on 2024-02-02

4257 The long noncoding RNA lnc-FANCI-2 restricts RAS signaling and phosphorylation of Akt and Erk in HPV16-infected cervical cancer cells

Liu, H.; Yu, L.; Majerciak, V.; Meyer, T.; Yi, M.; Johnson, P. F.; Cam, M.; Lowy, D. R.; Zheng, Z.-M.

10.1101/2024.02.01.578320 — cancer biology — Posted on 2024-02-02

4258 MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth

Cheng, O. J.; Lebish, E. J.; Jensen, O.; Jacenik, D.; Trivedi, S.; Cacioppo, J.; Aube, J.; Beswick, E. J.; Leung, D. T.

10.1101/2024.01.16.575894 — cancer biology — Posted on 2024-02-02

4259 A natural language processing system for the efficient extraction of cell markers

Cheng, P.; Peng, Y.; Zhang, X.; Chen, S.; Fang, B.; Li, Y.; Sun, Y.

10.1101/2024.01.30.578115 — bioinformatics — Posted on 2024-02-02

4260 Fast and scalable off-target assessment for CRISPR guide RNAs using partial matches

Schmitz, C.; Bradford, J.; Salomone, R.; Perrin, D.

10.1101/2024.02.01.578509 — bioinformatics — Posted on 2024-02-02

4261 ALTering cancer by triggering telomere replication stress through the stabilization of promoter G-quadruplex in SMARCAL1

Panda, S.; Roychowdhury, T.; Dutta, A.; Chakraborty, S.; Das, T.; Chatterjee, S.

10.1101/2024.02.01.578345 — biochemistry — Posted on 2024-02-02

4262 Drosophila Fog/Cta and T48 pathways have overlapping and distinct contributions to mesoderm invagination

Horo, U.; Clarke, D. N.; Martin, A. C.

10.1101/2024.02.02.578601 — developmental biology — Posted on 2024-02-02

4263 Mechanistic Insight into the Conformational Changes of Cas8 upon Binding to Different PAM Sequences in the Transposon-Encoded Type I-F CRISPR-Cas System

Alalmaie, A.; Khashan, R.

10.1101/2024.02.01.578494 — molecular biology — Posted on 2024-02-02

4264 Translational arrest and mRNA decay are independent activities of alphaherpesvirus virion host shutoff proteins

Eke, L.; Tweedie, A.; Cutts, S.; Wise, E. L.; Elliott, G.

10.1101/2024.02.02.578636 — microbiology — Posted on 2024-02-02

4265 Mendelian segregation and high recombination rates facilitate genetic analyses in Cryptosporidium parvum

Kimball, A.; Funkhouser-Jones, L.; Huang, W.; Xu, R.; Witola, W. H.; Sibley, L. D.

10.1101/2024.02.02.578536 — microbiology — Posted on 2024-02-02

4266 A pipeline for facile cloning of antibody Fv domains and their expression, purification, and characterization as recombinant His-tagged IgGs

Sinha, A.; Park, J. M.; Gulzar, N.; Pandya, D. N.; Wadas, T. J.; Scott, J. K.

10.1101/2024.01.31.578303 — immunology — Posted on 2024-02-02

4267 ALS-Associated TDP-43 Dysfunction Compromises UPF1-Dependent mRNA Metabolism Pathways Including Alternative Polyadenylation and 3'UTR Length

Alessandrini, F.; Wright, M.; Kurosaki, T.; Maquat, L.; Kiskinis, E.

10.1101/2024.01.31.578311 — neuroscience — Posted on 2024-02-02

4268 Older individuals do not show task specific variations in EEG band power and finger force coordination

Balasubramanian, E.; Balasubramanian, S.; SKM, V.

10.1101/2024.01.31.578126 — neuroscience — Posted on 2024-02-02

4269 Individualized functional connectivity markers associated with motor and mood symptoms of Parkinson's disease

Dahmani, L.; Bai, Y.; Zhang, W.; Ren, J.; Li, S.; Hu, Q.; Fu, X.; Ma, J.; Wei, W.; Wang, M.; Liu, H.; Wang, D.

10.1101/2024.01.31.578238 — neuroscience — Posted on 2024-02-02

4270 Aging is associated with a modality-specific decline in taste

Brown, E. B.; Lloyd, E.; Martin-Pena, A.; McFarlane, S.; Dahanukar, A.; Keene, A. C.

10.1101/2024.02.01.578408 — neuroscience — Posted on 2024-02-02

4271 AAV-based delivery of RNAi targeting Ataxin-2 improves survival, strength, and pathology in mouse models of rapidly and slowly progressive sporadic ALS

Amado, D. A.; Robbins, A. B.; Smith, A. R.; Whiteman, K. R.; Chillon Bosch, G.; Chen, Y.; Fuller, J. A.; Izda, A.; Nelson, S.; Dichter, A. I.; Monteys, A. M.; Davidson, B. L.

10.1101/2024.01.31.578314 — neuroscience — Posted on 2024-02-02

4272 Targeting Heterochromatin Eliminates Malignant Stem Cells in Chronic Myelomonocytic Leukemia Through Reactivation of Retroelements and Innate Immune pathways

Hidaoui, D.; Chelbi, R.; Bohm, M.; Porquet, A.; Polizou, A.; Alcazer, V.; Depil, S.; Imanci, A.; Morabito, M.; Renneville, A.; Selimoglu-Buet, D.; Thepot, S.; Itzykson, R.; Laplane, L.; Droin, N.; Trompouki, E.; Elvira-Matelot, E.; Solary, E.; PORTEU, F.

10.1101/2024.02.02.578583 — cancer biology — Posted on 2024-02-02

4273 High-throughput neural stem cell-based drug screening identifies S6K1 inhibition as a selective vulnerability in SHH-medulloblastoma

Zhou, L.; van Bree, N.; Boutin, L.; Moussaud, S.; Otrocka, M.; Wilhelm, M. T.

10.1101/2024.01.31.574335 — cancer biology — Posted on 2024-02-02

4274 Temperature-induced changes in protein interactions control RNA recruitment to G3BP1 condensates

Fischer, C. M.; Ausserwoger, H.; Sneideris, T.; Qian, D.; Scrutton, R.; Qamar, S.; St George-Hyslop, P.; Knowles, T. P. J.

10.1101/2024.02.02.578543 — biophysics — Posted on 2024-02-02

4275 RNA3DB: a dataset for training and benchmarking deep learning models for RNA structure prediction

Szikszai, M.; Rivas, E.; Magnus, M.; Sanghi, S.; Bouatta, N.; Kadyan, S.

10.1101/2024.01.30.578025 — bioinformatics — Posted on 2024-02-02

4276 A Cell Cycle-aware Network for Data Integration and Label Transferring of Single-cell RNA-seq and ATAC-seq

Liu, J.; Ma, J.; Wen, J.; zhou, X.

10.1101/2024.01.31.578213 — bioinformatics — Posted on 2024-02-02

4277 Improved nuclease-based prime editing by DNA repair modulation and pegRNA engineering

Antoniou, P.; Dacquay, L.; Selfjord, N.; Madeyski-Bengtson, K.; Loyd, A.-L.; Gordon, E.; Thom, G.; Hsieh, P.-P.; Wimberger, S.; Svikovic, S.; Firth, M.; Akrap, N.; Maresca, M.; Peterka, M.

10.1101/2024.02.01.578377 — bioengineering — Posted on 2024-02-02

4278 aMI-domain of Integrin Mac-1 Binds the Cytokine Pleiotrophin Using Multiple Mechanisms

NGUYEN, H.; ugarova, t.; Podolnikova, N.; Wang, X.

10.1101/2024.02.01.578455 — biochemistry — Posted on 2024-02-02

4279 Arsinothricin Biosynthesis Involving a Noncanonical Radical SAM Enzyme for C-As Bond Formation

Yao, Y.; He, J.; Dong, M.

10.1101/2024.02.01.577332 — biochemistry — Posted on 2024-02-02

4280 Conformational plasticity of a BiP-GRP94 chaperone complex

Brenner, J. C.; Zirden, L. C.; Almeida-Hernandez, Y.; Kaschani, F.; Kaiser, M.; Sanchez-Garcia, E.; Poepsel, S.; Hellerschmied, D.

10.1101/2024.02.01.578445 — biochemistry — Posted on 2024-02-02

4281 Molecular basis of ligand promiscuity, structural mimicry, and atypical dimerization in the chemokine receptors

Saha, S.; Sano, F. K.; Sharma, S.; Ganguly, M.; Saha, S.; Akasaka, H.; Kobayashi, T. A.; Zaidi, N.; Mishra, S.; Dalal, A.; Mohapatra, S.; Yadav, M.; Itoh, Y.; Leurs, R.; Chevigne, A.; Banerjee, R.; Shihoya, W.; Nureki, O.; SHUKLA, A. K.

10.1101/2024.02.01.578380 — biochemistry — Posted on 2024-02-02

4282 Host-pathogen Coadaptation by running with PAR protein

Zhu, S.; Zhou, X.; Qi, B.

10.1101/2024.01.31.578330 — evolutionary biology — Posted on 2024-02-02

4283 Comparative transcriptomic analyses reveal differences in the responses of diploid and triploid eastern oysters to environmental stress during a summer mortality event

Vaidya, R. V.; Bodenstien, S.; Rasulova, D.; La Peyre, J. F.; Kelly, M. W.

10.1101/2024.01.31.578323 — evolutionary biology — Posted on 2024-02-02

4284 DNA metabarcoding diet analysis in ruminants is quantitative and integrates feeding over several weeks

Kamenova, S.; Meyer, P.; Brysting, A. K.; Rescia, L.; Folkow, L. P.; Sundset, M. A.; Coissac, E.; Gusarova, G.

10.1101/2024.02.01.577814 — ecology — Posted on 2024-02-02

4285 Modeling nearshore-offshore water exchange in Lake Ontario

Hlevca, B.; Howell, E. T.; Valipour, R.; Madani, M.

10.1101/2024.01.31.578248 — ecology — Posted on 2024-02-02

4286 Depth-dependent dynamics of protist communities as an integral part of spring succession in a freshwater reservoir

Mukherjee, I.; Grujcic, V.; Salcher, M. M.; Znachor, P.; Seda, J.; Devetter, M.; Rychtecky, P.; Simek, K.; Shabarova, T.

10.1101/2024.02.01.578394 — ecology — Posted on 2024-02-02

4287 GSDMD pore formation regulates caspase-4 cleavage to limit IL-18 production in the intestinal epithelium

Bruce, J.; Li, L.; Tang, S.; Winsor, N.; Keely, S.; Philpott, D. J.; Girardin, S. E.

10.1101/2024.02.01.578487 — cell biology — Posted on 2024-02-02

4288 The DNA-repair protein APE1 participates with hnRNPA2B1 to motif-enriched and prognostic miRNA secretion

Mangiapane, G.; Notarangelo, M.; Canarutto, G.; Fabbiano, F.; Dalla, E.; Degrassi, M.; Antoniali, G.; Gualandi, N.; De Sanctis, V.; Piazza, S.; D'Agostino, V. G.; Tell, G.

10.1101/2024.02.02.578563 — molecular biology — Posted on 2024-02-02

4289 Select Bacterial Species Establish and Maintain Functionally Essential pH Gradient Profile within the Mosquito Larval Gut

Samanta, J.; Datta, S.

10.1101/2024.02.01.578530 — microbiology — Posted on 2024-02-02

4290 Characterization of severe fever with thrombocytopenia syndrome virus Japanese isolate YG1 strain quasispecies using reverse genetics approaches

Lokupathirage, S. M. W.; Muthusinghe, D. S.; Sarii, R. S.; Akanbi, O. A.; Shimizu, K.; Tsuda, Y.; Yoshimatsu, K.

10.1101/2024.02.01.578508 — microbiology — Posted on 2024-02-02

4291 Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea.

Melendez Sanchez, D.; Hernandez Juarez, L. E.; Ares Jimenez, M.; Mendez Tenorio, A.; Flores Luna, L.; Torres Lopez, J.; Camorlinga Ponce, M.

10.1101/2024.02.01.578430 — microbiology — Posted on 2024-02-02

4292 Antagonizing the SAMD9 pathway is key to myxoma virus host shut-off and immune evasion.

Raza, T.; Peterson, E.; Liem, J.; Liu, J.

10.1101/2024.02.01.578447 — microbiology — Posted on 2024-02-02

4293 A metagenomics-based survey of the virus diversity in mosquito vectors allows the first detection of Sindbis virus in Burkina Faso

Kabore, D.; Exbrayat, A.; charriat, f.; Soma, D. D.; Sawadogo, S.; Ouedraogo, G. A.; Tuaillon, E.; Van de Perre, P.; Baldet, T.; Dabire, R. K.; Gil, P.; Gutierrez, S.

10.1101/2024.02.02.578537 — microbiology — Posted on 2024-02-02

4294 Basic and translational science of cyst wall proteins of the eye pathogen Acanthamoeba

Kanakapura Sundararaj, B.; Goyal, M.; Samuelson, J.

10.1101/2024.02.02.578540 — microbiology — Posted on 2024-02-02

4295 Label-free and reference region-free X-ray cross-beta index for quantifying protein aggregates of neurodegenerative diseases

Suresh, K.; Dahal, E.; Badano, A.

10.1101/2024.01.31.578167 — neuroscience — Posted on 2024-02-02

4296 Dynamic formation of a posterior-to-anterior peak-alpha-frequency gradient driven by two distinct processes

Smith, M. K.; Grabowecky, M.; Suzuki, S.

10.1101/2024.01.31.578276 — neuroscience — Posted on 2024-02-02

4297 Negative relationship between inter-regional interaction and regional power: a resting fMRI study

Lee, T.-W.; Tramontano, G.

10.1101/2024.01.31.578128 — neuroscience — Posted on 2024-02-02

4298 Quantification of beta cell carrying capacity in prediabetes

Woller, A.; Tamir, Y.; Bar, A.; Mayo, A.; Rein, M.; Godneva, A.; Mendelson Cohen, N.; Segal, E.; Toledano, Y.; Shilo, S.; Gonze, D.; Alon, U.

10.1101/2024.01.31.578144 — systems biology — Posted on 2024-02-02

4299 Thermodynamics determines the coupling between growth and byproduct production

Oftadeh, O.; Hatzimanikatis, V.

10.1101/2024.01.31.578201 — systems biology — Posted on 2024-02-02

4300 GNN4DM: A Graph Neural Network-based method to identify overlapping functional disease modules

Gezsi, A.; Antal, P.

10.1101/2024.01.30.578064 — systems biology — Posted on 2024-02-02

4301 Selective degradation of multimeric proteins via chemically induced proximity to TRIM21

Lu, P.; Cheng, Y.; Xue, L.; Ren, X.; Chen, C.; Li, J.; Wu, Q.; Sun, S.; Hou, J.; Jia, W.; Li, C.; Qi, X.; Huang, N.; Han, T.

10.1101/2024.01.31.578122 — pharmacology and toxicology — Posted on 2024-02-02

4302 Disconnection Between Microvascular Damage and Neurodegeneration in Early Diabetic Retinopathy

Yang, Q.; Yasvoina, M.; Olvera-Barrios, A.; Mendes, J.; Zhu, M.; Egan, C.; Tufail, A.; Fruttiger, M.

10.1101/2024.01.31.577770 — pathology — Posted on 2024-02-02

4303 MYBL2 drives prostate cancer plasticity and identifies CDK2 as a therapeutic vulnerability in RB1-loss and neuroendocrine prostate cancer

Ellis, L.; German, B.; Singh, J. N.; Burkhart, D. L.; Sheahan, A.; Bergom, H.; Morel, K. L.; Beltran, H.; Hwang, J.; Lawrenson, K.

10.1101/2024.01.31.578216 — cancer biology — Posted on 2024-02-02

4304 Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer

Aparicio, L.; Crowley, L.; Christin, J. R.; Laplaca, C. J.; Hibshoosh, H.; Rabadan, R.; Shen, M. M.

10.1101/2024.01.30.578066 — cancer biology — Posted on 2024-02-02

4305 Translational T-box riboswitches bind tRNA by modulating conformational flexibility

Campos-Chavez, E.; Paul, S.; Zhou, Z.; Alonso, D.; Verma, A. R.; Fei, J.; Mondragon, A.

10.1101/2024.02.02.578613 — biophysics — Posted on 2024-02-02

4306 SPIRED-Fitness: an end-to-end framework for the prediction of protein structure and fitness from single sequence

Chen, Y.; Xu, Y.; Liu, D.; Xing, Y.; Gong, H.

10.1101/2024.01.31.578102 — bioinformatics — Posted on 2024-02-02

4307 NMDtxDB: Data-driven identification and annotation of human NMD target transcripts

Britto-Borges, T.; Gehring, N. H.; Boehm, V.; Dieterich, C.

10.1101/2024.01.31.578146 — bioinformatics — Posted on 2024-02-02

4308 Physicochemical Principles Driving Small Molecule Binding to RNA

Allen, T. E. H.; McDonagh, J. L.; Broncel, M.; Bryant, C. J.; Incarnato, D.; Vasudevan, A.; Khan, R. T.

10.1101/2024.01.31.578268 — bioinformatics — Posted on 2024-02-02

4309 Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation

Farra, Y. M.; Matz, J.; Wilker, H.; Kim, H.; Rivera, C. F.; Vlahos, J.; Ramkhelawon, B.; Oakes, J.; Bellini, C.

10.1101/2024.01.30.578110 — bioengineering — Posted on 2024-02-02

4310 Metabolic priming of GD2 TRAC-CAR T cellsduring manufacturing promotes memory phenotypes while enhancing persistence

Cappabianca, D.; Pham, D.; Forsberg, M. H.; Bugel, M.; Tommasi, A.; Lauer, A.; Vidugiriene, J.; Hrdlicka, B.; McHale, A.; Sodji, Q.; Skala, M. C.; Capitini, C. M.; Saha, K.

10.1101/2024.01.31.575774 — bioengineering — Posted on 2024-02-02

4311 Identifying compositional and density changes across the Murine and Human Dentin-enamel Junction

Truhlar, M.; Rosenberg, B.; Katebifar, S.; Kroger, R.; Deymier, A.

10.1101/2024.01.30.578062 — bioengineering — Posted on 2024-02-02

4312 A combination of two-enzyme system and enzyme engineering improved the activity of a new PET hydrolase identified from soil bacterial genome

Mabashi-Asazuma, H.; Hirai, M.; Sakurai, S.; Ide, K.; Kogawa, M.; Matsushita, A.; Hosokawa, M.; Tsuda, S.

10.1101/2024.02.01.578500 — bioengineering — Posted on 2024-02-02

4313 miR-210 is essential to retinal homeostasis in fruit flies and mice

Colaianni, D.; Virga, F.; Tisi, A.; Stefanelli, C.; Zaccagnini, G.; Cusumano, P.; Sales, G.; Ivan, M.; Martelli, F.; Taverna, D.; Mazzone, M.; Bertolucci, C.; Maccarone, R.; De Pitta, C.

10.1101/2024.01.30.577988 — genetics — Posted on 2024-02-02

4314 Screening of associated bacteria of Alexandrium catenella on affecting PSTs production and influence mechanism

Zou, S.; Yu, X.; Sun, T.; Wu, X.

10.1101/2024.01.31.578139 — ecology — Posted on 2024-02-02

4315 Botryococcus braunii reduces algal grazing losses to Daphnia and Poterioochromonas through both chemical and physical interference

Thomas, P. K.; Arn, F.; Freiermuth, M.; Narwani, A.

10.1101/2024.02.01.576556 — ecology — Posted on 2024-02-02

4316 Genetic interference with HvNotch provides new insights into the role of the Notch-signalling pathway for developmental pattern formation in Hydra

Pan, Q.; Mercker, M.; Klimovich, A.; Wittlieb, J.; Marciniak-Czochra, A.; Boettger, A.

10.1101/2024.01.31.578171 — developmental biology — Posted on 2024-02-02

4317 FGF2 promotes the expansion of parietal mesothelial progenitor pools and inhibits BMP4-mediated smooth muscle cell differentiation

Hwang, Y.; Shimamura, Y.; Tanaka, J.; Miura, A.; Sawada, A.; SARMAH, H.; Shimizu, D.; Kondo, Y.; Ninish, Z.; Yamada, K.; Mori, M.

10.1101/2024.01.31.577512 — developmental biology — Posted on 2024-02-02

4318 Notch is Required for Neural Progenitor Proliferation During Embryonic Eye Regrowth

Guerin, D. J.; Gutierrez, B.; Zhang, B.; Tseng, K.

10.1101/2024.01.31.577915 — developmental biology — Posted on 2024-02-02

4319 TBX3 is essential to establish the posterior boundary of anterior genes and up-regulate posterior genes with HAND2 during onset of limb bud development

Soussi, G.; Girdziusaite, A.; Jhanwar, S.; Palacio, V.; Sheth, R.; Zeller, R.; Zuniga, A.

10.1101/2024.01.30.577998 — developmental biology — Posted on 2024-02-02

4320 Somite-independent regeneration of the axolotl primary body axis

Masselink, W.; Gerber, T.; Falcon, F.; Deshayes, T.; Papadopoulos, S.-C.; Pende, M.; Singh Jamwal, V.; Taniguchi-Sugiura, Y.; Lin, T.-Y.; Kurth, T.; Wang, J.; Arendt, D.; Fei, J.-F.; Treutlein, B.; Tanaka, E. M.; Murawala, P.

10.1101/2024.01.31.577464 — developmental biology — Posted on 2024-02-02

4321 Notch controls early temporal factor expression to control timing of Mushroom body neuroblast apoptosis

Branham, K.; Sood, C.; Doyle, S.; Pahl, M.; Siegrist, S.

10.1101/2024.01.31.578279 — developmental biology — Posted on 2024-02-02

4322 CELL CYCLE STATE PREDICTION USING GRAPH NEURAL NETWORKS

Acharya, S.; Ganguly, A.; Sarkar, R.; Jose, A.

10.1101/2024.01.30.577893 — cell biology — Posted on 2024-02-02

4323 Disruption of DLL4/NOTCH1 Causes Dysregulated PPARγ/AKT Signaling in Pulmonary Arterial Hypertension

Awad, K. S.; Wang, S.; Dougherty, E. J.; Keshavarz, A.; Demirkale, C. Y.; Yu, Z.-X.; Miller, L.; Elinoff, J. M.; Danner, R. L.

10.1101/2024.01.31.578230 — cell biology — Posted on 2024-02-02

4324 Molecular mechanism of complement inhibition by the trypanosome receptor ISG65

Cook, A. D.; Carrington, M.; Higgins, M. K.

10.1101/2023.04.27.538609 — microbiology — Posted on 2024-02-02

4325 Pre-existing Immunity to Influenza Aids Ferrets in Developing Stronger and Broader Vaccine-induced Antibody Responses

Ge, Y.; Lu, Y.; Allen, J.; Einav, T.; Nkaleke, D. I.; Bai, F.; Handel, A.; Ross, T.; Shen, Y.

10.1101/2024.01.31.578203 — immunology — Posted on 2024-02-02

4326 Autoinflammatory patients with Golgi-trapped CDC42 exhibit intracellular trafficking defects leading to STING hyperactivation

Iannuzzo, A.; Delafontaine, S.; El Masri, R.; Tacine, R.; Prencipe, G.; Nishitani-Isa, M.; van Wijck, R. T.; Bhuyan, F.; Rasheed, A. A. d. J.; Coppola, S.; van Daele, P. L.; Insalaco, A.; Goldbach-Mansky, R.; Yasumi, T.; Tartaglia, M.; Meyts, I.; Delon, J.

10.1101/2024.01.31.578189 — immunology — Posted on 2024-02-02

4327 The Switchmaze: an open-design device for measuring motivation and drive switching in mice

Hartmann, C.; Mahajan, A.; Borges, V.; Razenberg, L.; Thoennes, Y.; Karnani, M. M.

10.1101/2024.01.31.578188 — neuroscience — Posted on 2024-02-02

4328 The role of hidden hearing loss in tinnitus: insights from early markers of peripheral hearing damage

Devolder, P.; Keppler, H.; Keshishzadeh, S.; Taghon, B.; Dhooge, I.; Verhulst, S.

10.1101/2024.01.31.578195 — neuroscience — Posted on 2024-02-02

4329 Model mimicry limits conclusions about neural tuning and can mistakenly imply unlikely priors

Wolff, M. J.; Rademaker, R. L.

10.1101/2024.01.31.578040 — neuroscience — Posted on 2024-02-02

4330 Histological comparison of repeated mild weight drop and lateral fluid percussion injury models of traumatic brain injury (TBI) in female and male rats.

Vita, S. M.; Cruise, S. C.; Gilpin, N. W.; Molina, P. E.

10.1101/2024.01.31.578177 — neuroscience — Posted on 2024-02-02

4331 Open-Source Platform for Kinematic Analysis of Mouse Forelimb Movement

Berezhnoi, D.; Chehade, H. D.; Chu, H.-y.

10.1101/2024.01.31.578239 — neuroscience — Posted on 2024-02-02

4332 Single-Cell Peripheral Immunoprofiling of Lewy Body Disease in a Multi-site Cohort

Phongpreecha, T.; Mathi, K.; Cholerton, B.; Fox, E. J.; Espinosa, C.; Hwang, L.-J. L.; Sigal, N.; Gajera, C.; Berson, E.; Perna, A.; Xie, F.; Shu, C.-H.; Hazra, D.; Reincke, M.; Chung, P.; Channappa, D.; Dunn, J.; Kipp, L. B.; Poston, K. L.; Montine, K. S.; Maecker, H. T.; Aghaeepour, N.; Montine, T. J.

10.1101/2024.01.30.578082 — neuroscience — Posted on 2024-02-02

4333 Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B

Touvier, T.; Veneri, F. A.; Claessens, A.; Ferri, C.; Mastrangelo, R.; Sorgiati, N.; Bianchi, F.; Valenzano, S.; Del Carro, U.; Rivellini, C.; Duong, P.; Shy, M. E.; Kelly, J. W.; Svaren, J.; Wiseman, R. L.; D'Antonio, M.

10.1101/2024.01.31.577760 — neuroscience — Posted on 2024-02-02

4334 Hypothalamic dopamine neuron activity is modulated by caloric states and amphetamine abuse in zebrafish larvae

Bansal, P.; Jung, E. E.

10.1101/2024.01.31.578277 — neuroscience — Posted on 2024-02-02

4335 mTORC1 ACTIVATION IN PRESUMED CLASSICAL MONOCYTES:OBSERVED CORRELATES WITH HUMAN SIZE VARIATION AND NEUROPSYCHIATRIC DISEASE

Berner, K.; Oz, N.; Kaya, A.; Acharjee, A.; Berner, J.

10.1101/2024.01.31.578140 — neuroscience — Posted on 2024-02-02

4336 Cardiomyocyte PGC-1α enables physiological adaptations to endurance exercise through suppression of GDF15 and cardiac atrophy

Khetarpal, S. A.; Li, H.; Vitale, T.; Rhee, J.; Grauvogel, L.; Castro, C.; Mittenbühler, M. J.; Houstis, N. E.; Vargas-Castillo, A.; Smythers, A. L.; Liu, J.; Curtin, C.; Sprenger, H.-G.; Blackmore, K. A.; Kuznetsov, A.; Freeman, R.; Bogoslavski, D.; Ellinor, P. T.; Asnani, A.; Dumesic, P. A.; Puigserver, P.; Roh, J. D.; Spiegelman, B. M.; Rosenzweig, A.

10.1101/2024.01.30.578093 — physiology — Posted on 2024-02-02

4337 MXRA8 promotes adipose tissue whitening to drive obesity

Jia, W.; Giwa, R.; Moley, J. R.; Smith, G. I.; Petersen, M. C.; Field, R. L.; Abousaway, O.; Kim, A. S.; Coffey, S. R.; Varnum, S.; Wright, J. M.; Zhang, X.; Krysa, S.; Lodhi, I. J.; Abumrad, N. A.; Klein, S.; Diamond, M. S.; Brestoff, J. R.

10.1101/2024.01.31.578211 — physiology — Posted on 2024-02-02

4338 Perinatal ampicillin administration modulates murine bile acid metabolism in vivo - an observational study

Thomas, S. P.; Askarian, F.; Kousha, A.; Suzuki, E.; Tsai, C. M.; Liu, G.; Nizet, V.; Dorrestein, P. C.; Tsunoda, S.

10.1101/2024.01.31.578215 — pharmacology and toxicology — Posted on 2024-02-02

4339 Cardiovascular and Locomotor Effects of Binary Mixtures of Common Bath Salts Constituents: Studies with Methylone, MDPV, and Caffeine in Rats

Seaman, R. W.; Galindo, D. G.; Stinson, B. T.; Sulima, A.; Rice, K. C.; Javors, M. A.; Ginsburg, B. C.; Collins, G. T.

10.1101/2024.01.31.578069 — pharmacology and toxicology — Posted on 2024-02-02

4340 The Effect of Adrenalectomy on Bleomycin-Induced Pulmonary Fibrosis in Mice

McGovern, J.; Perry, C.; Ghincea, A.; Shao, S.; Herzog, E. L.; Sun, H.

10.1101/2024.01.31.577771 — pathology — Posted on 2024-02-02

4341 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers, tested on DNA plectoneme formation dynamics

Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.

10.1101/2024.01.18.576226 — biophysics — Posted on 2024-02-02

4342 Towards Equitable MHC Binding Predictions: Computational Strategies to Assess and Reduce Data Bias

Singh, M.; Glynn, E.; Ghersi, D.

10.1101/2024.01.30.578103 — bioinformatics — Posted on 2024-02-02

4343 TopEC: Improved classification of enzyme function by a localized 3D protein descriptor and 3D Graph Neural Networks

van der Weg, K.; Merdivan, E.; Piraud, M.; Gohlke, H.

10.1101/2024.01.31.578271 — bioinformatics — Posted on 2024-02-02

4344 Phenomics Assistant: An Interface for LLM-based Biomedical Knowledge Graph Exploration

O'Neil, S. T.; Schaper, K.; Elsarboukh, G.; Reese, J. T.; Moxon, S. A. T.; Harris, N. L.; Munoz-Torres, M. C.; Robinson, P. N.; Haendel, M. A.; Mungall, C. J.

10.1101/2024.01.31.578275 — bioinformatics — Posted on 2024-02-02

4345 Integrated Closed-loop Control of Bio-actuation for Proprioceptive Bio-hybrid Robots

Filippi, M.; Balciunaite, A.; georgopoulou, A.; Paniagua, P.; Drescher, F.; Nie, M.; Takeuchi, S.; Clemens, F.; Katzschmann, R.

10.1101/2024.01.30.577987 — bioengineering — Posted on 2024-02-02

4346 Chromosome segment scanning for gain- or loss-of-function screening (CHASING) and its application in metabolic engineering

Xia, Y.; Sun, L.; Liang, Z.; Han, Z.; Li, J.; Guo, Y.; Dong, P.; Huo, Y.-X.; Guo, S.

10.1101/2024.01.31.578163 — bioengineering — Posted on 2024-02-02

4347 Scalable single-cell pooled CRISPR screens with conventional knockout vector libraries

Islam, M.; Yang, Y.; Simmons, A. J.; Xu, Y.; Fisher, E.; Deng, W.; Grieb, B.; Molina, P.; Caestecker, C. d.; Ramirez-Solano, M. A.; Liu, Q.; Tansey, W.; Macara, I. G.; Rathmell, J.; Coffey, R. J.; Lau, K.

10.1101/2024.02.01.578192 — genomics — Posted on 2024-02-02

4348 A hierarchical Bayesian interaction model to estimate cell-type-specific methylation quantitative trait loci incorporating priors from cell-sorted bisulfite sequencing data

Cheng, Y.; Cai, B.; Li, H.; Zhang, X.; D'Souza, G.; Shrestha, S.; Edmonds, A.; Meyers, J.; Fischl, M.; Kassaye, S.; Anastos, K.; Cohen, M.; Aouizerat, B. E.; Xu, K.; Zhao, H.

10.1101/2024.02.01.578272 — genetics — Posted on 2024-02-02

4349 Potential role of microRNAs in regulating transcriptional profile, and sculpting development and metabolism in cavefish.

Biswas, T.; Hassan, H.; Rohner, N.

10.1101/2024.01.30.578051 — evolutionary biology — Posted on 2024-02-02

4350 Selfish herd effects in aggregated caterpillars and their interaction with warning signals

Kersh-Mellor, R.; Montgomery, S. H.; McLellan, C. F.

10.1101/2024.01.31.578162 — ecology — Posted on 2024-02-02

4351 Utilising affordable smartphones and open-source time-lapse photography for monitoring pollinators

Stefan, V.; Workman, A.; Cobain, J. C.; Rakosy, D.; Knight, T. M.

10.1101/2024.01.31.578173 — ecology — Posted on 2024-02-02

4352 Transcriptional responses to priority effects in nectar yeast

Chappell, C. R.; Goddard, P.; Golden, L.; Hernandez, J.; Ortiz Chavez, D.; Hossine, M.; Herrera Paredes, S.; Fukami, T. R.; Dhami, M.

10.1101/2024.01.30.578081 — ecology — Posted on 2024-02-02

4353 Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism

Moorwood, K.; Smith, F. M.; Garfield, A. S.; Cowley, M.; Holt, L. J.; Daly, R. J.; Ward, A.

10.1101/2024.01.31.578179 — developmental biology — Posted on 2024-02-02

4354 Synthesis of 5-Benzylamino and 5-Alkylamino-substituted Pyrimidoquinoline Derivatives as CSNK2A Inhibitors with Antiviral Activity

Asressu, K. H.; Smith, J. L.; Dickmander, R. J.; Moorman, N. J.; Wellnitz, J.; Popov, K. I.; Axtman, A. D.; Willson, T. M.

10.1101/2024.01.30.578037 — cell biology — Posted on 2024-02-02

4355 HSP60 chaperone deficiency disrupts the mitochondrial matrix proteome and dysregulates cholesterol synthesis

Comert, C.; Kjaer-Sorensen, K.; Hansen, J.; Carlsen, J.; Just, J.; Meany, B. F.; Oestergaard, E.; Luo, Y.; Oxvig, C.; Schmidt-Laursen, L.; Palmfeldt, J.; Fernandez-Guerra, P.; Bross, P.

10.1101/2024.01.31.578131 — cell biology — Posted on 2024-02-02

4356 Dissecting reprogramming heterogeneity at single-cell resolution using scTF-seq

Liu, W.; Saelens, W.; Rainer, P.; Biocanin, M.; Gardeux, V.; Gralak, A.; van Mierlo, G.; Russeil, J.; Liu, T.; Chen, W.; Deplancke, B.

10.1101/2024.01.30.577921 — cell biology — Posted on 2024-02-02

4357 Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria

Beauchemin, E. T.; Hunter, C.; Maurice, C. F.

10.1101/2024.02.01.578403 — microbiology — Posted on 2024-02-02

4358 IRAK4 autophosphorylation controls inflammatory signaling by activating IRAK oligomerization

Srikanth, N.; Deliz-Aguirre, R.; Gola, D. K.; Bilay, M.; Ziska, E.; Taylor, M. J.

10.1101/2023.12.21.572799 — immunology — Posted on 2024-02-02

4359 Recapitulating memory B cell responses in a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies

Jeger-Madiot, R.; Planas, D.; Staropoli, I.; Kervevan, J.; Mary, H.; Collina, C.; Fonseca, B. F.; Debarnot, H.; Robinot, R.; Gellenoncourt, S.; Schwartz, O.; Ewart, L.; Bscheider, M.; Gobaa, S.; Chakrabarti, L. A.

10.1101/2024.02.02.578553 — immunology — Posted on 2024-02-02

4360 The cortical heartbeat-evoked potential is modulated by heart rate in a task and mental effort dependent manner

Aprile, F.; Simoes, M.; Henriques, J.; de Carvalho, P.; Castelo-Branco, M.; Sel, A.; Ribeiro, M. J.

10.1101/2024.01.31.578137 — neuroscience — Posted on 2024-02-02

4361 Multistability and predominant double-positive states in a four node mutually repressive network: a case study of Th1/Th2/Th17/T-reg differentiation

Duddu, A. S.; Andreas, E.; BV, H.; Grover, K.; Singh, V. R.; Hari, K.; Jhunjhunwala, S.; Cummins, B.; Gedeon, T.; Jolly, M. K.

10.1101/2024.01.30.575880 — systems biology — Posted on 2024-02-02

4362 No cardiac phase bias for threat perception under naturalistic conditions in immersive virtual reality

Klotzsche, F.; Motyka, P.; Molak, A.; Sahula, V.; Darmova, B.; Byrnes, C.; Fajnerova, I.; Gaebler, M.

10.1101/2024.01.31.578172 — physiology — Posted on 2024-02-02

4363 Renal-Derived Human sPRR Does Not Increase Blood Pressure in High Fat Diet Mice

Arthur, G.; Biel, K.; Osborn, J.; Hinds, T. D.; Gong, M.; Loria, A.

10.1101/2024.01.30.577981 — physiology — Posted on 2024-02-02

4364 Moth resonant mechanics are tuned to wingbeat frequency and energetic demands.

Wold, E.; Aiello, B.; Harris, M.; Sikandar, U. B.; Lynch, J.; Gravish, N.; Sponberg, S.

10.1101/2024.01.30.578003 — physiology — Posted on 2024-02-02

4365 Beta2 -Adrenergic Agonists in Treatment for Parkinsonism, with Implications for Neurodegenerative and Neoplastic Disorders.

Inchiosa, M. A.

10.1101/2024.01.12.575406 — pharmacology and toxicology — Posted on 2024-02-02

4366 Development of a LRRC15-Targeted Radio-Immunotheranostic Approach to Deplete Pro-tumorigenic Mechanisms and Immunotherapy Resistance

Storey, C. M.; Altai, M.; Lueckerath, K. M.; Zedan, W.; Zhu, H.; Trajkovic-Arsic, M.; Park, J. E.; Peekhaus, N.; Siveke, J.; Lilljebjorn, H.; Abou, D.; Marks, H. L.; Ulmert, E.; Lilja, H.; Ridley, A.; Safi, M.; Yuen, C.; Geres, S.; Mao, L.; Cheng, M.; Czernin, J.; Herrmann, K.; Bentolila, L.; Yang, X.; Fioretos, T.; Graeber, T.; Sjostrom, K.; Damoiseaux, R.; Thorek, D. L.; Ulmert, D.

10.1101/2024.01.30.577289 — pharmacology and toxicology — Posted on 2024-02-02

4367 Loss of TIM4-Dependent Efferocytosis in Kupffer CellsPromotes Liver Fibrosis in Nonalcoholic Steatohepatitis

Shi, H.; Wang, X.; Gerlach, B.; Yurdagul, A.; Moore, M.; Mirshahi, F.; Ronzoni, L.; Sanyal, A.; Valenti, L.; Lin, C.-S.; Tabas, I.

10.1101/2024.01.30.578023 — pathology — Posted on 2024-02-02

4368 Mechanical confinement governs phenotypic plasticity in melanoma

Hunter, M. V.; Montal, E.; Ma, Y.; Moncada, R.; Yanai, I.; Koche, R. P.; White, R. M.

10.1101/2024.01.30.577120 — cancer biology — Posted on 2024-02-02

4369 A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia

Dong, Z.; Sepulveda, H.; Vazquez, L. J. A.; Blouin, C.; Fernandez, J.; Binder, M.; Chou, W.-C.; Tien, H.-F.; Faulkner, G. J.; Myers, S. A.; Patnaik, M.; Rao, A.

10.1101/2024.01.30.578015 — cancer biology — Posted on 2024-02-02

4370 Comprehensive characterization of the viscoelastic properties of Bovine Submaxillary Mucin (BSM) hydrogels and the effect of additives

Rulff, H.; Schmidt, R. F.; Wei, L.-F.; Fentker, K.; Kerkhoff, Y.; Mertins, P.; Mall, M. A.; Lauster, D.; Gradzielski, M.

10.1101/2024.01.17.576019 — biophysics — Posted on 2024-02-02

4371 TULIP - a Transformer based Unsupervised Language model for Interacting Peptides and T-cell receptors that generalizes to unseen epitopes

Meynard-Piganeau, B.; Feinauer, C.; Weigt, M.; Walczak, A. M.; Mora, T.

10.1101/2023.07.19.549669 — bioinformatics — Posted on 2024-02-02

4372 SPRITE: improving spatial gene expression imputation with gene and cell networks

Sun, E. D.; Ma, R.; Zou, J.

10.1101/2024.01.31.578269 — bioinformatics — Posted on 2024-02-02

4373 Revision of splicing variants in the DMD gene

Davydenko, K.; Skoblov, M.; Filatova, A.

10.1101/2024.01.31.578175 — genetics — Posted on 2024-02-02

4374 The role of learned song in the evolution and speciation of Eastern and Spotted towhees

Leon Du'Mottuchi, X.; Creanza, N.

10.1101/2023.05.15.540821 — evolutionary biology — Posted on 2024-02-02

4375 Detection of prions from spiked and free-ranging carnivore feces

Inzalaco, H. N.; Brandell, E. E.; Wilson, S. P.; Hunsaker, M.; Stahler, D. R.; Woelfel, K.; Walsh, D. P.; Nordeen, T.; Storm, D. J.; Lichtenberg, S. S.; Turner, W. C.

10.1101/2023.07.31.551307 — ecology — Posted on 2024-02-02

4376 Geometric and demographic effects explain contrasting fragmentation-biodiversity relationships across scales

Gelber, S.; Blowes, S. A.; Chase, J. M.; Huth, A.; Schurr, F. M.; Tietjen, B.; Zeller, J. W.; May, F.

10.1101/2024.02.01.577731 — ecology — Posted on 2024-02-02

4377 Sf3b4 mutation in Xenopus tropicalis causes RNA splicing defects followed by massive gene dysregulation that disrupt cranial neural crest development

Griffin, C.; Coppenrath, K.; Khan, D.; Lin, Z.; Horb, M.; Saint-Jeannet, J.-P.

10.1101/2024.01.31.578190 — developmental biology — Posted on 2024-02-02

4378 Reactive oxygen species suppress phagocyte surveillance by oxidizing cytoskeletal regulators

Ferling, I.; Pfalzgraf, S.; Moutounet, L.; Qiu, L.; Li, I.; Zhou, Y.; Freeman, S. A.; Grinstein, S.

10.1101/2024.01.31.578237 — cell biology — Posted on 2024-02-02

4379 Context-dependent functions of mitochondria protein quality control in lung

Xu, L.; Tan, C.; Barr, J.; Talaba, N.; Verheyden, J.; Chin, J. S.; Gaboyan, S.; Advani, I.; Elgamal, R. M.; Gaulton, K. J.; Lin, G.; Afshar, K.; Golts, E.; Meier, A.; Alexander, L. C.; Borok, Z.; Shen, Y.; Chung, W. K.; McCulley, D. J.; Sun, X.

10.1101/2022.12.08.519642 — cell biology — Posted on 2024-02-02

4380 m6a methylation orchestrates IMP1 regulation of microtubules during human neuronal differentiation

Klein, P.; Harley, J.; Crook, H.; Serna, S. E.; Petric-Howe, M.; Roumeliotis, T. I.; Choudhary, J. S.; Chakrabarti, A. M.; Luisier, R.; Patani, R.; Ramos, A.

10.1101/2023.09.12.557394 — molecular biology — Posted on 2024-02-02

4381 Microbial remineralization processes during post-spring-bloom excess phosphate in the northern Baltic Sea

Vanharanta, M.; Santoro, M.; Villena-Alemany, C.; Piiparinen, J.; Piwosz, K.; Grossart, H.-P.; Labrenz, M.; Spilling, K.

10.1101/2024.02.02.577174 — microbiology — Posted on 2024-02-02

4382 Presence of phage-plasmids in multiple serovars of Salmonella enterica

Nair, S.; Barker, C. R.; Bird, M.; Greig, D. R.; Collins, C.; Painset, A.; Chattaway, M.; Pickard, D.; Larkin, L.; Gharbia, S.; Didelot, X.; Ribeca, P.

10.1101/2024.02.02.574330 — microbiology — Posted on 2024-02-02

4383 Pigs are highly susceptible to but do not transmit mink-derived highly pathogenic avian influenza virus H5N1 clade 2.3.4.4b

Kwon, T.; Trujillo, J. D.; Carossino, M.; Lyoo, E. L.; McDowell, C. D.; Cool, K.; Matias-Ferreyra, F. S.; Jeevan, T.; Morozov, I.; Gaudreault, N. N.; Balasuriya, U.; Webby, R. J.; Osterrieder, N.; Richt, J. A.

10.1101/2023.12.13.571575 — microbiology — Posted on 2024-02-02

4384 Influenza A Virus Disruption of Dendritic Cell-Natural Killer Cell Crosstalk Impacts Activation of Helper and Cytotoxic T cell Subsets

Morson, C. A.; Uppalapati, C. K.; Lopez, B. S.; Kronstad, L. M.

10.1101/2024.02.01.578467 — immunology — Posted on 2024-02-02

4385 Machine learning reveals the control mechanics of the insect wing hinge

Melis, J. M.; Siwanowicz, I.; Dickinson, M. H.

10.1101/2023.06.29.547116 — neuroscience — Posted on 2024-02-02

4386 Biochemical, biomarker, and behavioral characterization of the GrnR493X mouse model of frontotemporal dementia

Smith, D. M.; Aggarwal, G.; Niehoff, M. L.; Jones, S. A.; Banerjee, S.; Farr, S. A.; Nguyen, A. D.

10.1101/2023.05.27.542495 — neuroscience — Posted on 2024-02-02

4387 A Retrospective Analysis of Career Outcomes in Neuroscience

Ullrich, L. E.; Ogawa, J. R.; Jones-London, M. D.

10.1101/2024.02.01.578220 — scientific communication and education — Posted on 2024-02-02

4388 Mutations in HUA2 restore flowering in the Arabidopsis trehalose 6-phosphate synthase1 (tps1) mutant

Zeng, L.; Zacharaki, V.; Wang, Y.; Schmid, M.

10.1101/2024.01.31.578264 — plant biology — Posted on 2024-02-02

4389 DePARylation is critical for S phase progression and cell survival

Nie, L.; Wang, C.; Huang, M.; Liu, X.; Feng, X.; Tang, M.; Li, S.; Hang, Q.; Teng, H.; Shen, X.; Ma, L.; Gan, B.; Chen, J.

10.1101/2023.07.31.551317 — cancer biology — Posted on 2024-02-02

4390 Tumor sialylation controls effective anti-cancer immunity in breast cancer

Mereiter, S.; Jonsson, G.; Oliveira, T.; Helm, J.; Hoffmann, D.; Abeln, M.; Jochum, A.-K.; Jochum, W.; Kellner, M. J.; Feith, M.; Tkalec, V.; Wasilewska, K.; Jiao, J.; Emsenhuber, L.; Holstein, F.; Obenauf, A.; Lordello, L.; Scoazec, J.-Y.; Kroemer, G.; Zitvogel, L.; Ali, O. H.; Flatz, L.; Gerardy-Schahn, R.; Muenster-Kuehnel, A.; Stadlmann, J.; Penninger, J. M.

10.1101/2023.09.20.558571 — cancer biology — Posted on 2024-02-02

4391 NIEND: Neuronal Image Enhancement through Noise Disentanglement

Zhao, Z.-H.; Liu, Y.

10.1101/2023.10.21.563265 — bioinformatics — Posted on 2024-02-02

4392 nanoBERT: A deep learning model for gene agnostic navigation of the nanobody mutational space

Hadsund, J.; Satlawa, T.; Janusz, B.; Shan, L.; Zhou, L.; Rottger, R.; Krawczyk, K.

10.1101/2024.01.31.578143 — bioinformatics — Posted on 2024-02-02

4393 An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma

Holm, A.; Graus, M.; Wylie-Sears, J.; Borgelt, L.; Tan, J. W. H.; Nasim, S.; Chung, L.; Jain, A.; Sun, M.; Sun, L.; Brouillard, P.; Lekwuttikarn, R.; Kozakewich, H.; Qi, Y. J.; Teng, J.; Mulliken, J.; Vikkula, M.; Francois, M.; Bischoff, J.

10.1101/2024.01.29.577829 — molecular biology — Posted on 2024-02-02

4394 Thalamic feedback shapes brain responses evoked by cortical stimulation in mice and humans

Russo, S.; Claar, L.; Marks, L.; Krishnan, G.; Furregoni, G.; Zauli, F. M.; Hassan, G.; Solbiati, M.; d'Orio, P.; Mikulan, E.; Sarasso, S.; Rosanova, M.; Sartori, I.; Bazhenov, M.; Pigorini, A.; Massimini, M.; Koch, C.; Rembado, I.

10.1101/2024.01.31.578243 — neuroscience — Posted on 2024-02-02

4395 Mice born preterm develop gait dystonia and reduced cortical parvalbumin immunoreactivity

Gemperli, K.; Folorunso, F.; Norin, B.; Joshua, R.; Hill, C.; Rykowski, R.; Galindo, R.; Aravamuthan, B. R.

10.1101/2024.02.01.578353 — neuroscience — Posted on 2024-02-02

4396 WITHDRAWN: How rate information is collectively coded in input to the cerebellum: a hypothesis and simulation

Gilbert, M.; Rasmussen, A.

10.1101/2023.06.25.546423 — neuroscience — Posted on 2024-02-02

4397 Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies

Danielson, M.; Nicolai, C. J.; Vo, T. T.; Wolf, N.; Burke, T. P.

10.1101/2024.01.30.578087 — cancer biology — Posted on 2024-02-02

4398 A lipidome Aging Clock shows Age Acceleration in individuals with Autism

Latumalea, D.; Unfried, M.; Barardo, D. G.; Gruber, J.; Kennedy, B. K.

10.1101/2024.02.01.578331 — neuroscience — Posted on 2024-02-02

4399 SAXS DATA BASED GLYCOSYLATED MODELS OF HUMAN ALPHA-1-ACID GLYCORPROTEIN, A KEY PLAYER IN HEALTH, DISEASE AND DRUG CIRCULATION

Kalidas, N.; Peddada, N.; Pandey, K.; Ashish, F.

10.1101/2024.02.01.578488 — biophysics — Posted on 2024-02-02

4400 GlycansToGraphs: visualizing and simplifying complex mass spectra

Jacquet, C.; Bonner, R.; Hopfgartner, G.

10.1101/2024.01.31.578148 — bioinformatics — Posted on 2024-02-02

4401 Flow Cytometry Strategies for Rapidly Characterizing Heterogeneous Adipocyte Populations in 3D In Vitro Constructs

Struss, M. M.; Anvari, G.; Bellas, E.

10.1101/2024.01.30.578065 — bioengineering — Posted on 2024-02-02

4402 Bio-orthogonal Glycan Imaging of Culture Cells and Whole Animal C. elegans with Expansion Microscopy

Kuo, J. C.-H.; Colville, M. J.; Sorkin, M. R.; Kuo, J. L. K.; Huang, L.-T.; Thornlow, D. N.; Beacham, G. M.; Hollopeter, G.; DeLisa, M. P.; Alabi, C. A.; Paszek, M. J.

10.1101/2024.02.01.578333 — bioengineering — Posted on 2024-02-02

4403 Heterologous expression and characterization of mutant cellulase from indigenous strain of Aspergillus niger

Zafar, M.; Ahmad, W.; Anwar, Z.; Mehmood Ashraf, N.; Ahmad, S.

10.1101/2024.01.31.578261 — biochemistry — Posted on 2024-02-02

4404 The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated beta-catenin degradation and through a mechanism independent of beta-catenin stability

McKenna, J. K.; Wu, Y.; Sonkusre, P.; Lebensohn, A. M.

10.1101/2024.02.02.578552 — genetics — Posted on 2024-02-02

4405 The homie insulator has sub-elements with different insulating and long-range pairing properties

Fujioka, M.; Ke, W.; Schedl, P.; Jaynes, J. B.

10.1101/2024.02.01.578481 — genetics — Posted on 2024-02-02

4406 Selection of different parameters to study epistatic effect between heat shock and slightly deleterious mutations in the most fragile stage of embryogenesis Cyprinus carpio L.

Kuzmin, A. V.; Skripskaya, V.; Lobanova, V.; Brodovaya, P.; Mukhitov, M.; Tarasova, A.; Popadin, K.; Mikhailova, A. G.; Vinogradov, E.; Mugue, N.; Balashov, D.

10.1101/2024.01.23.576732 — ecology — Posted on 2024-02-02

4407 Manipulation of the Nuclear Envelope-Associated Protein SLAPDuring Mammalian Brain Development Affects Cortical Lamination and Exploratory Behavior

Mestres, I.; Atabay, A.; Escolano, J.-C.; Arndt, S.; Schmidtke, K.; Einsiedel, M.; Patsonis, M.; Castro, L. A.; Yun, M.; Bernhardt, N.; Taubenberger, A. V.; Calegari, F.

10.1101/2024.01.31.578288 — developmental biology — Posted on 2024-02-02

4408 Role of Fibronectin in Postnatal Skeletal Development

Dinesh, N. E. H.; Baratang, N. P.; Rosseau, J.; Mohapatra, R.; Li, L.; Mahalingam, R.; Tiedemann, K.; Campeau, P. M.; Reinhardt, D. P.

10.1101/2024.02.01.578475 — developmental biology — Posted on 2024-02-02

4409 Stratification of viral shedding patterns in saliva of COVID-19 patients

Park, H.; Raiki, Y.; Iwanami, S.; Kim, K.; Ejima, K.; Nakamura, N.; Aihara, K.; Miyazaki, Y.; Umeyama, T.; Miyazawa, K.; Morita, T.; Watashi, K.; Brooke, C. B.; Ke, R.; Iwami, S.; Miyazaki, T.

10.1101/2024.01.30.578034 — microbiology — Posted on 2024-02-02

4410 Simultaneous interneuron labeling reveals population-level interactions among parvalbumin, somatostatin, and pyramidal neurons in cortex

Potter, C. T.; Bassi, C. D.; Runyan, C. A.

10.1101/2023.01.09.523298 — neuroscience — Posted on 2024-02-02

4411 Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

Yasa, S.; Butz, E.; Colombo, A.; Chandrachud, U.; Montore, L.; Sheridan, S.; Mueller, S. A.; Lichtenthaler, S. F.; Tahirovic, S.; Cotman, S.

10.1101/2024.02.01.578018 — neuroscience — Posted on 2024-02-02

4412 Schizophrenia risk gene ZNF804A controls ribosome localization and synaptogenesis in developing human neurons

Sichlinger, L.; Wulf, M.; Dutan Polit, L.; Nasser, F.; Duarte, R. R.; Powell, T. R.; Marcus, K.; Vernon, A. C.; Srivastava, D. P.

10.1101/2024.02.02.578424 — neuroscience — Posted on 2024-02-02

4413 Reduced expression of calcium-binding proteins in the anteroventral thalamic nucleus of individuals with Down syndrome

Perry, J. C.; Vann, S.

10.1101/2024.02.01.578360 — neuroscience — Posted on 2024-02-02

4414 A Multimodal Characterization of Low-Dimensional Thalamocortical Structural Connectivity Patterns

John, A.; Hettwer, M. D.; Schaare, H. L.; Saberi, A.; Bayrak, S.; Wan, B.; Royer, J.; Bernhardt, B. C.; Valk, S. L.

10.1101/2024.02.01.578366 — neuroscience — Posted on 2024-02-02

4415 Chemogenetic silencing reveals presynaptic Gi/o protein-mediated inhibition of synchronized activity in the developing hippocampus in vivo

Graf, J.; Samiee, A.; Flossmann, T.; Holthoff, K.; Kirmse, K.

10.1101/2024.02.02.578550 — neuroscience — Posted on 2024-02-02

4416 Neural Dynamics of the Processing of Speech Features: Evidence for a Progression of Features from Acoustic to Sentential Processing

Karunathilake, I. M. D.; Brodbeck, C.; Bhattasali, S.; Resnik, P.; Simon, J. Z.

10.1101/2024.02.02.578603 — neuroscience — Posted on 2024-02-02

4417 The temporal specificity of BOLD fMRI is systematically related to anatomical and vascular features of the human brain

Gomez, D. E. P.; Polimeni, J. R.; Lewis, L. D.

10.1101/2024.02.01.578428 — neuroscience — Posted on 2024-02-02

4418 Distinct functional roles of distributed cortical representations for working memory storage

Chopurian, V.; Weber, S. B.; Christophel, T.

10.1101/2024.02.02.578618 — neuroscience — Posted on 2024-02-02

4419 Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice

de Assis, L. V.; Harder, L.; Inderhees, J.; Johren, O.; Mittag, J.; Oster, H.

10.1101/2024.01.30.577730 — physiology — Posted on 2024-02-02

4420 Force-transducing molecular ensembles at growing microtubule tips control mitotic spindle size

Chu, L.-Y.; Stedman, D.; Gannon, J.; Cox, S.; Pobegalov, G.; Molodtsov, M.

10.1101/2024.02.01.578443 — biophysics — Posted on 2024-02-02

4421 Onset of Mismatch Repair by the Human Mismatch Repair Protein, MutSbeta for a Biosensing Device

Devlin, J.; Madigan, J.; Macwan, I.

10.1101/2024.01.31.578329 — biophysics — Posted on 2024-02-02

4422 Mechanically Tunable, Compostable, Healable and Scalable Engineered Living Materials

Manjula-Basavanna, A.; Joshi, N.; Duraj-Thatte, A.

10.1101/2024.01.31.578234 — bioengineering — Posted on 2024-02-02

4423 A genetic locus in the gut microbe Bacteroides thetaiotaomicron encodes activities consistent with mucin-O-glycoprotein processing and plays a critical role in N-acetylgalactosamine metabolism

Ndeh, D.; Nakjang, S.; Kwiatkowski, K.; Koropatkin, N. M.; Hirt, R. P.; Bolam, D.

10.1101/2024.02.01.578401 — biochemistry — Posted on 2024-02-02

4424 Temporal and spatial dynamics of Plasmodium falciparum clonal lineages in Guyana

Vanhove, M.; Schwabl, P.; Clementson, C.; Early, A. M.; Laws, M.; Anthony, F.; Florimond, C.; Mathieu, L.; James, K.; Knox, C.; Singh, N.; Buckee, C. O.; Musset, L.; Niles-Robin, R.; Cox, H.; Neafsey, D. E.

10.1101/2024.01.31.578156 — genomics — Posted on 2024-02-02

4425 Field evaluation of a volatile pyrethroid spatial repellent and etofenprox-treated clothing for outdoor protection against forest malaria vectors in Cambodia

Vajda, E. A.; Ross, A.; Doum, D.; Fairbanks, E.; Chitnis, N. A.; Hii, J.; Moore, S. J.; Richardson, J.; Macdonald, M.; Sovannaroth, S.; Kimheng, P.; McIver, D. J.; Tatarsky, A.; Lobo, N. F.

10.1101/2024.01.30.577940 — ecology — Posted on 2024-02-02

4426 In vitro antimicrobial activity of non-aureus Staphylococci and Mammaliicocci against Staphylococcus aureus and Streptococcus uberis and their relationship with the presence of intramammary infections in organic dairy cows

Pena Mosca, F.; Gaire, T. N.; Dean, C. J.; Manriquez, D.; Pinedo, P.; Noyes, N.; Caixeta, L. S.

10.1101/2024.02.01.578391 — microbiology — Posted on 2024-02-02

4427 Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin

Egge, S. L.; Rizvi, S. A.; Simar, S. R.; Alcade-Rico, M.; Martinez, J. R.; Hanson, B. M.; Dinh, A. Q.; de Paula Baptista, R.; Tran, T. T.; Shelburne, S. A.; Munita, J. M.; Arias, C. A.; Hakki, M.; Miller, W. R.

10.1101/2024.01.30.578008 — microbiology — Posted on 2024-02-02

4428 IL-3-driven T cell-basophil crosstalk enhances anti-tumor immunity

Wei, J.; Mayberry, C. L.; Lv, X.; Hu, F.; Sears, J. D.; Khan, T.; Logan, N. A.; Wilson, J. J.; Chaussabel, D.; CHANG, C.-H.

10.1101/2024.02.01.578302 — immunology — Posted on 2024-02-02

4429 Decision-making processes in perceptual learning depend on effectors

Ivanov, V.; Manenti, G.; Plewe, S. S.; Kagan, I.; Schwiedrzik, C. M.

10.1101/2022.06.29.498152 — neuroscience — Posted on 2024-02-02

4430 KvS regulatory subunits confer drug resistance to Kv2 channels

Stewart, R. G.; Marquis, M. J.; Jo, S.; Ferns, M.; Sack, J. T.

10.1101/2024.01.31.578214 — neuroscience — Posted on 2024-02-02

4431 Microtubules ensure transport of vegetative nuclei and sperm cells by fine-tuning their home positions

Motomura, K.; Tsuchi, H.; Komojiri, M.; Matsumoto, A.; Sugi, N.; Susaki, D.; Takeda, A.; Kinoshita, T.; Maruyama, D.

10.1101/2024.01.31.578224 — plant biology — Posted on 2024-02-02

4432 Caspase prime-side active-site characterization with non-hydrolyzable peptides assists in the design of a caspase-7-selective irreversible probe.

Solania, A.; Xu, J. H.; Wolan, D. W.

10.1101/2024.01.30.578085 — biophysics — Posted on 2024-02-02

4433 The kinematics and aerodynamics of hinged wing of honeybees during takeoff

Li, Y.; Hao, Z.; Yang, B.; Gong, W.; Yin, B.; Wang, C.; Song, J.; Yin, L.

10.1101/2024.01.30.577934 — biophysics — Posted on 2024-02-02

4434 Seedless: On-the-fly pulse calculation for NMR experiments

Baldwin, A. J.; Jones, J.; Buchanan, C.; Karunanithy, G.; Casablancas-Antras, V.; Poh, A.; Davis, B. G.

10.1101/2024.01.31.578133 — biophysics — Posted on 2024-02-02

4435 Distinct platelet interactions with soluble and immobilized von Willebrand factor modulate platelet adhesion and aggregation with differential impact on hemostasis and thrombosis

Chen, Y.; Ruggeri, Z. M.

10.1101/2024.01.31.578078 — biophysics — Posted on 2024-02-02

4436 Leveraging Machine Learning-Guided Molecular Simulations Coupled with Experimental Data to Decipher Membrane Binding Mechanisms of Aminosterols

Muscat, S.; Errico, S.; Danani, A.; Chiti, F.; Grasso, G.

10.1101/2024.01.31.578042 — biophysics — Posted on 2024-02-02

4437 Calcium-driven In Silico Inactivation of a Human Olfactory Receptor

Pirona, L.; Ballabio, F.; Alfonso-Prieto, M.; Capelli, R.

10.1101/2024.01.31.578070 — biophysics — Posted on 2024-02-02

4438 Both the transcriptional activator, Bcd, and transcriptional repressor, Cic, form small mobile oligomeric clusters in early fly embryo nuclei

Zhang, L.; Hodgins, L.; Sakib, S.; Mahmood, A.; Romero, C. P.; Marmion, R. A.; Dostatni, N.; Fradin, C.

10.1101/2024.01.30.578077 — biophysics — Posted on 2024-02-02

4439 DiffTopo: Fold exploration using coarse grained protein topology representations

Correia, B.

10.1101/2024.02.01.578456 — biophysics — Posted on 2024-02-02

4440 Insights on the GPCR helix 8 solution structure and orientation using a neurotensin receptor 1 peptide

Bower, J. B.; Robson, S. A.; Ziarek, J. J.

10.1101/2024.01.31.578299 — biophysics — Posted on 2024-02-02

4441 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers, tested on DNA plectoneme formation dynamics

Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.

10.1101/2024.01.18.576226 — biophysics — Posted on 2024-02-02

4442 Adaptive Regularized Tri-Factor Non-Negative Matrix Factorization for Cell Type Deconvolution

Liu, T.; Liu, C.; Li, Q.; Zheng, X.; Zou, F.

10.1101/2023.12.07.570631 — bioinformatics — Posted on 2024-02-02

4443 Syntactic Sugars: Crafting a Regular Expression Framework for Glycan Structures

Bennett, A. R.; Bojar, D.

10.1101/2024.02.01.578383 — bioinformatics — Posted on 2024-02-02

4444 Microphysiological Modeling of Vascular Adipose Tissue for Multi-Throughput Applications

Struss, M. M.; Bellas, E.

10.1101/2024.01.30.578061 — bioengineering — Posted on 2024-02-02

4445 Simulated Microgravity Enhances Adipocyte Maturation and Glucose Uptake via Increased Cortical Actin Remodeling

Anvari, G.; Struss, M. M.; Bellas, E.

10.1101/2024.01.30.578049 — bioengineering — Posted on 2024-02-02

4446 Can mechanistic constraints on recombination reestablishment explain the long-term maintenance of degenerate sex chromosomes?

Lenormand, T.; Roze, D.

10.1101/2023.02.17.528909 — evolutionary biology — Posted on 2024-02-02

4447 Tactile versus Motor Imagery: Differences in Corticospinal Excitability Assessed with single-pulse TMS

Morozova, M.; Nasibullina, A.; Yakovlev, L.; Syrov, N.; Kaplan, A.; Lebedev, M.

10.1101/2023.10.16.562530 — neuroscience — Posted on 2024-02-02

4448 Using synchronized brain rhythms to bias memory-guided decisions

Stout, J. J.; George, A. E.; Kim, S.; Hallock, H. L.; Griffin, A. L.

10.1101/2023.04.02.535279 — neuroscience — Posted on 2024-02-02

4449 A Novel Therapeutic Approach using CXCR3 Blockade to Treat Immune Checkpoint Inhibitor-mediated Myocarditis

Huang, Y. V.; Lee, D.; Sun, Y.; Chou, H.; Xu, B.; Lin, Z.; Branche, C.; Bayer, A. L.; Waliany, S.; Neal, J.; Wakelee, H.; Witteles, R.; Nguyen, P.; Graves, E. E.; Alcaide, P.; Berry, G. J.; Wu, S. M.; Zhu, H.

10.1101/2024.01.30.576279 — cell biology — Posted on 2024-02-02

4450 Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes

Bitar, S.; Baumann, T.; Weber, C.; Abusaada, M.; Rojas-Charry, L.; Ziegler, P.; Schettgen, T.; Randerath, I. E.; Venkataramani, V.; Michalke, B.; Arena, G.; Krueger, R.; Zhang, L.; Methner, A.

10.1101/2023.09.28.559909 — neuroscience — Posted on 2024-02-02

4451 Dynamic modes of Notch transcription hubs conferring memory and stochastic activation revealed by live imaging the co-activator Mastermind

deHaro-Arbona, F. J.; Roussos, C.; Baloul, S.; Townson, J. M.; Gomez-Lamarca, M.; Bray, S. J.

10.1101/2023.08.10.552629 — developmental biology — Posted on 2024-02-02

4452 Analysis of arbuscular mycorrhizal fungi (AMF) community composition associated with alkaline saline sodic soils

Marquez, N.; Irazoqui, J. M.; Ciacci, M. B.; Amadio, A. F.; Fernandez, F. D.; Giachero, M. L.

10.1101/2024.02.01.578375 — plant biology — Posted on 2024-02-02

4453 Being confident in confidence scores : calibration in deep learning models for camera trap image sequences

Dussert, G.; Chamaille-Jammes, S.; Dray, S.; Miele, V.

10.1101/2023.11.10.566512 — ecology — Posted on 2024-02-02

4454 Jointly looking to the past and the future in visual working memory

Liu, B.; Alexopoulou, Z.-S.; van Ede, F.

10.1101/2023.01.30.526235 — neuroscience — Posted on 2024-02-02

4455 A computational model for individual differences in non-reinforced learning for individual items

Salomon, T.; Itzkovitch, A.; Daw, N. D.; Schonberg, T.

10.1101/2022.03.20.484477 — neuroscience — Posted on 2024-02-02

4456 Oct4 is a gatekeeper of epithelial identity by regulating cytoskeletal organization in skin keratinocytes

Christofidou, E.; Tomazou, M.; Voutouri, C.; Michael, C.; Stylianopoulos, T.; Spyrou, G. M.; Strati, K.

10.1101/2023.05.05.539557 — cell biology — Posted on 2024-02-02

4457 The regulation of polar flagella assembly in Pseudomonas putida

Pulido-Sanchez, M.; Leal-Morales, A.; Lopez-Sanchez, A.; Cava, F.; Govantes, F.

10.1101/2023.12.15.571843 — microbiology — Posted on 2024-02-02

4458 A septo-hypothalamic-medullary circuit directs stress-induced analgesia

Shah, D.; Sharma, P. R.; Agarwal, R.; Barik, A.

10.1101/2023.01.30.526171 — neuroscience — Posted on 2024-02-02

4459 Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin

Oevel, K.; Hohensee, S.; Kumar, A.; Rosas-Brugada, I.; Bartolini, F.; Soykan, T.; Haucke, V.

10.1101/2023.10.12.561997 — neuroscience — Posted on 2024-02-02

4460 Progressive alterations in polysomal architecture and activation of ribosome stalling relief factors in a mouse model of Huntington's disease

Martin-Solana, E.; Diaz-Lopez, I.; Mohamedi, Y.; Ventoso, I.; Fernandez, J.-J.; Fernandez-Fernandez, M. R.

10.1101/2021.12.13.472357 — neuroscience — Posted on 2024-02-02

4461 D2/D3 dopamine supports the precision of mental state inferences and self-relevance of joint social outcomes

Barnby, J. M.; Bell, V.; Deeley, Q.; Mehta, M. A.; Moutoussis, M. M.

10.1101/2023.05.02.539031 — neuroscience — Posted on 2024-02-02

4462 Specific amygdala and hippocampal subfield volumes in social anxiety disorder and their relation to clinical characteristics; an international mega-analysis

Ntwatwa, Z.; Spreckelmeyer, J.; Bas-Hoogendam, J. M.; van Honk, J.; Mufford, M.; Boraxbekk, C.-J.; Fouche, J.-P.; Frick, A.; Furmark, T.; Klumpp, H.; Lochner, C.; Luan Phan, K.; Mansson, K. N. T.; Pannekoek, N.; Peterburs, J.; Roelofs, K.; Roos, A.; Straube, T.; van Steenbergen, H.; Van Tol, M.-J.; Veltman, D. J.; van der Wee, N. J. A.; Stein, D. J.; Ipser, J.; Groenewold, N.

10.1101/2024.01.29.576056 — neuroscience — Posted on 2024-02-02

4463 A Comprehensive Human Embryogenesis Reference Tool using Single-Cell RNA-Sequencing Data

Zhao, C.; Plaza Reyes, A.; Schell, J. P.; Weltner, J.; Ortega, N.; Zheng, Y.; Bjorklund, A. K.; Baque-Vidal, L.; Sokka, J.; Trokovic, R.; Cox, B. J.; Rossant, J.; Fu, J.; Petropoulos, S.; Lanner, F.

10.1101/2021.05.07.442980 — developmental biology — Posted on 2024-02-02

4464 Rescaling protein-protein interactions improves Martini 3 for flexible proteins in solution

Thomasen, F. E.; Skaalum, T.; Kumar, A.; Srinivasan, S.; Vanni, S.; Lindorff-Larsen, K.

10.1101/2023.05.29.542689 — biophysics — Posted on 2024-02-01

4465 Evolutionary conservation of mechanical strain distributions in functional transitions of protein structures

Sartori, P.; Leibler, S.

10.1101/2023.02.07.527482 — biophysics — Posted on 2024-02-02

4466 Quantitative omnigenic model discovers interpretable genome-wide associations

Ruzickova, N.; Hledik, M.; Tkacik, G.

10.1101/2024.02.01.578486 — genomics — Posted on 2024-02-01

4467 Scalable ultra-high-throughput single-cell chromatin and RNA sequencing reveals gene regulatory dynamics linking macrophage polarization to autoimmune disease

Lobato-Moreno, S.; Yildiz, U.; Claringbould, A.; Servaas, N. H.; Vlachou, E. P.; Arnold, C.; Bauersachs, H. G.; Campos-Fornes, V.; Prummel, K. D.; Noh, K. M.; Marttinen, M.; Zaugg, J. B.

10.1101/2023.12.26.573253 — genomics — Posted on 2024-02-02

4468 Tbx1 haploinsufficiency causes brain metabolic and behavioral anomalies in adult mice which are corrected by vitamin B12 treatment

Caterino, M.; Paris, D.; Torromino, G.; Costanzo, M.; Flore, G.; Tramice, A.; Golini, E.; Mandillo, S.; Cavezza, D.; Angelini, C.; Ruoppolo, M.; Motta, A.; De Leonibus, E.; Baldini, A.; Illingworth, E.; Lania, G.

10.1101/2024.02.01.578212 — genetics — Posted on 2024-02-01

4469 Decoding Huge Phage Diversity: A Taxonomic Classification of Lak Megaphages

Cook, R.; Crisci, M. A.; Pye, H. V.; Telatin, A.; Adriaenssens, E. M.; Santini, J. M.

10.1101/2024.02.01.578382 — microbiology — Posted on 2024-02-01

4470 Antibiotics at Clinical Concentrations Show Limited Effectivity Against Acute and Chronic Intracellular S. aureus Infections in Osteocytes

Zelmer, A. R.; Gunn, N. J.; Yang, D.; Solomon, L. B.; Nelson, R.; Kidd, S. P.; Richter, K.; Atkins, G. J.

10.1101/2023.12.17.572089 — microbiology — Posted on 2024-02-02

4471 Memory's gatekeeper: the role of PFC in the encoding of familiar events

Guerreiro, I. C.; Clopath, C. C.

10.1101/2024.02.01.578356 — neuroscience — Posted on 2024-02-01

4472 Task Activation Results in Regional 13C-Lactate Signal Increase in the Human Brain

Uthayakumar, B.; Cappelletto, N. I. C.; Bragagnolo, N. D.; Chen, A. P.; Ma, N.; Perks, W. J.; Endre, R.; Tam, F.; Graham, S. J.; Heyn, C.; Keshari, K. R.; Soliman, H.; Cunningham, C. H.

10.1101/2024.02.01.577808 — neuroscience — Posted on 2024-02-01

4473 Subcortical origin of nonlinear sound encoding in auditory cortex

Lohse, M.; King, A. J.; Willmore, B. D.

10.1101/2024.02.01.578402 — neuroscience — Posted on 2024-02-01

4474 Optogenetic mapping of rhythmic phase-dependentexcitability in the mouse striatum

Mohapatra, M.; Carmichael, J. E.; van der Meer, M. A.

10.1101/2024.02.01.578473 — neuroscience — Posted on 2024-02-01

4475 The role of NMDA receptors in memory and prediction incultured neural networks

Lamberti, M.; van Putten, M. J. A. M.; Marzen, S.; le Feber, J.

10.1101/2024.02.01.578348 — neuroscience — Posted on 2024-02-01

4476 High-throughput Microfluidic 3D Outer Blood-Retinal Barrier Model in a 96-Well Format: Analysis of Cellular Interactions and Barrier Function in Retinal Health and Disease

Kim, J.; Song, Y.; Jolly, A.; Hwang, T.; Kim, S.; Lee, B.; Jang, J.; Jo, D. H.; Baek, K.; Liu, T.-L.; Yoo, S.; Jeon, N. L.

10.1101/2023.12.01.569537 — bioengineering — Posted on 2024-02-01

4477 Analyzing the link between RNA secondary structures and R-loop formation with tree polynomials

Liu, P.; Lusk, J.; Jonoska, N.; Vazquez, M.

10.1101/2023.09.24.559224 — molecular biology — Posted on 2024-02-01

4478 The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons.

Xiao, W.; Halabi, R.; Lin, C.-H.; Nazim, M.; Yeom, K.-H.; Black, D. L.

10.1101/2024.02.01.578240 — molecular biology — Posted on 2024-02-01

4479 Opposing roles of resident and infiltrating immune cells in the defence against Legionella longbeachae via IL-18R/IFN-γ/ROS axis

Oberkircher, L. M.; Scheiding, V. M.; Rafeld, H. L.; Hanssen, E.; Hansen, J. N.; Fleischmann, M. J.; Kessler, N. M.; Pitsch, D.; Wachten, D.; Kastenmueller, W.; Brown, A. S.; Hartland, E.; van Driel, I. R.; Ng, G. Z.; Garbi, N.

10.1101/2024.01.31.578217 — immunology — Posted on 2024-02-01

4480 In-silico Drug Repurposing pipeline for Epilepsy: Integrating Deep Learning and Structure-based Approaches

Lv, X.; Wang, J.; Yuan, Y.; Pan, L.; Guo, J.

10.1101/2024.01.29.577686 — pharmacology and toxicology — Posted on 2024-02-01

4481 Elastin Recoil is Driven by the Hydrophobic Effect

Jamhawi, N. M.; Koder, R. L.; Wittebort, R. J.

10.1101/2023.03.07.531587 — biophysics — Posted on 2024-02-01

4482 OpenCell: A Low-cost, Open-Source, 3-in-1 device for DNA Extraction

Gupta, A.; Yu, J.; Challita, E. J.; Standeven, J.; Bhamla, M. S.

10.1101/2023.09.18.558349 — bioengineering — Posted on 2024-02-01

4483 Challenging the Astral mass analyzer - going beyond 5200 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity.

Bubis, J. A.; Arrey, T. N.; Damoc, E.; Delanghe, B.; Slovakova, J.; Sommer, T. M.; Kagawa, H.; Pichler, P.; Rivron, N. C.; Mechtler, K.; Matzinger, M.

10.1101/2024.02.01.578358 — biochemistry — Posted on 2024-02-01

4484 Target-aware Molecule Generation for Drug Design Using a Chemical Language Model

Xia, Y.; Wu, K.; Deng, P.; Liu, R.; Zhang, Y.; Guo, H.; Cui, Y.; Pei, Q.; Wu, L.; Xie, S.; Chen, S.; Lu, X.; Hu, S.; Wu, J.; Chan, C.-K.; Chen, S.; Zhou, L.; Yu, N.; Liu, H.; Guo, J.; Qin, T.; Liu, T.-Y.

10.1101/2024.01.08.574635 — biochemistry — Posted on 2024-02-01

4485 From sequence to molecules: Feature sequence-based genome mining uncovers the hidden diversity of bacterial siderophore pathways

Gu, S.; Shao, Y.; Rehm, K.; Bigler, L.; Zhang, D.; He, R.; Xu, R.; Shao, J.; Jousset, A.; Friman, V.-P.; Bian, X.; Wei, Z.; Kummerli, R.; Li, Z.

10.1101/2023.10.30.564663 — genomics — Posted on 2024-02-01

4486 Late stages of the Zika virus life cycle are impaired by a selective TRPML2 agonist

Schwickert, K. K.; Glitscher, M.; Bender, D.; Murra, R.; Schwickert, K.; Pfalzgraf, S.; Schirmeister, T.; Hellmich, U. A.; Hildt, E.

10.1101/2024.02.01.578205 — cell biology — Posted on 2024-02-01

4487 Transcriptome analysis of the tardigrade Hypsibius exemplaris exposed to the DNA-damaging agent bleomycin

Yoshida, Y.; Hirayama, A.; Arakawa, K.

10.1101/2024.02.01.578372 — molecular biology — Posted on 2024-02-01

4488 Topology-informed regulatory element collections coordinate cell identity gene expression programs

Lv, J.; Maher, K. A.; Veluchamy, A.; Kim, Y.; Dong, L.; Ju, B.; Valentine, V.; Valentine, M.; Burden, S.; Easton, J.; Pounds, S. B.; Abraham, B.

10.1101/2024.02.01.578210 — molecular biology — Posted on 2024-02-01

4489 The Impact of Mismatches Within the RNA: DNA Hybrid in the Transposon-Encoded Type I-F CRISPR-Cas System

Alalmaie, A.; Khashan, R.

10.1101/2024.02.01.578492 — molecular biology — Posted on 2024-02-01

4490 NELF coordinates Pol II transcription termination and DNA replication initiation

Nakayama, C.; Daigaku, Y.; Aoi, Y.; Fang, Q.; Kimura, H.; Shilatifard, A.; Tellier, M.; Nojima, T.

10.1101/2024.01.31.578294 — molecular biology — Posted on 2024-02-01

4491 Programmable RNA writing with trans-splicing

Schmitt-Ulms, C.; Kayabolen, A.; Manero-Carranza, M.; Zhou, N.; Donnelly, K.; Nuccio, S. P.; Kato, K.; Nishimasu, H.; Gootenberg, J. S.; Abudayyeh, O. O.

10.1101/2024.01.31.578223 — molecular biology — Posted on 2024-02-01

4492 Towards understanding of allostery in MALT1: a possible role of interdomain motions as revealed by NMR and AlphaFold

Wallerstein, J.; Han, X.; Levkovets, M.; Lesovoy, D.; Malmodin, D.; Mirabello, C.; Wallner, B.; Sun, R.; Sandalova, T.; Agback, P.; Karlsson, G.; Achour, A.; Agback, T.; Orekhov, V.

10.1101/2024.02.01.578365 — molecular biology — Posted on 2024-02-01

4493 Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid

Yung, C.; Zhang, Y.; Kuhn, M.; Armstrong, R. J.; Olyaei, A.; Aloia, M.; Scottoline, B.; Andres, S. F.

10.1101/2023.09.03.556067 — molecular biology — Posted on 2024-02-01

4494 First report and characterization of a plasmid-encoded blaSFO-1 in a multi-drug resistant Aeromonas hydrophila clinical isolate

Skwor, T.; Jones, D. C.; Cahak, C.; Newton, R. J.

10.1101/2024.02.01.578490 — microbiology — Posted on 2024-02-01

4495 Alpha-synuclein overexpression can drive microbiome dysbiosis in mice

Sampson, T. R.; Wallen, Z. D.; Won, W.-J.; Standaert, D. G.; Payami, H.; Harms, A. S.

10.1101/2024.02.01.578464 — microbiology — Posted on 2024-02-01

4496 Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

Zhou, X.; Shen, X.; Johnson, J.; Spakowicz, D.; Agnello, M.; Zhou, W.; Avina, M.; Honkala, A.; Chleilat, F.; Chen, S. J.; Cha, K.; Leopold, S.; Zhu, C.; Chen, L.; Lyu, L.; Hornburg, D.; Wu, S.; Zhang, X.; Jiang, C.; Jiang, L.; jiang, l.; Jian, R.; Brooks, A. W.; Wang, M.; Contrepois, K.; Gao, P.; Schussler-Fiorenza Rose, S. M.; Tran, T. D. B.; Nguyen, H.; Celli, A.; Hong, B.-Y.; Bautista, E. J.; Dorsett, Y.; Kavathas, P.; zhou, y.; Sodergren, E.; Weinstock, G. M.; Snyder, M. P.

10.1101/2024.02.01.577565 — microbiology — Posted on 2024-02-01

4497 The proteome is a terminal electron acceptor

Flamholz, A. I.; Goyal, A.; Fischer, W. W.; Newman, D. K.; Phillips, R.

10.1101/2024.01.31.578293 — microbiology — Posted on 2024-02-01

4498 Pediatric human nose organoids demonstrate greater susceptibility, epithelial responses, and cytotoxicity than adults during RSV infection.

Aloisio, G. M.; Nagaraj, D.; Murray, A. M.; Schultz, E. M.; McBride, T.; Aideyan, L.; Nicholson, E. G.; Henke, D.; Ferlic-Stark, L.; Rajan, A.; Kambal, A.; Johnson, H.; Mosa, E.; Stossi, F.; Blutt, S. E.; Piedra, P. A.; Avadhanula, V.

10.1101/2024.02.01.578466 — microbiology — Posted on 2024-02-01

4499 Biogenesis of cytochromes c and c1 in the electron transport chain of malaria parasites

Garcia-Guerrero, A. E.; Marvin, R. G.; Blackwell, A. M.; Sigala, P. A.

10.1101/2024.02.01.575742 — microbiology — Posted on 2024-02-01

4500 Restricted intake of sulfur-containing amino acids reversed the hepatic injury induced by excess Desulfovibrio through gut-liver axis

Zhou, L.; Lu, G.; Nie, Y.; Ren, Y.; Shi, J.-S.; Xue, Y.; Xu, Z.-H.; Geng, Y.

10.1101/2024.02.01.578326 — microbiology — Posted on 2024-02-01

4501 Curing of a field strain of Salmonella enterica serovar Infantis isolated from poultry from its highly stable pESI like plasmid

Gruzdev, N.; Katz, C.; Yadid, I.

10.1101/2024.02.01.578384 — microbiology — Posted on 2024-02-01

4502 Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria

Beauchemin, E. T.; Hunter, C.; Maurice, C. F.

10.1101/2024.02.01.578403 — microbiology — Posted on 2024-02-01

4503 Bacterial community structure analysis on Listeria monocytogenes inoculated spinach leaves is affected by PCR based methods to exclude chloroplast co-amplification

Culliney, P.; Schmalenberger, A.

10.1101/2024.02.01.578417 — microbiology — Posted on 2024-02-01

4504 When no answer is better than a wrong answer: a causal perspective on batch effects

Bridgeford, E. W.; Powell, M.; Kiar, G.; Noble, S.; Chung, J.; Panda, S.; Lawrence, R.; Xu, T.; Milham, M.; Caffo, B.; Vogelstein, J. T.

10.1101/2021.09.03.458920 — neuroscience — Posted on 2024-02-01

4505 Marine heatwaves disrupt ecosystem structure and function via altered food webs and energy flux

Gomes, D. G. E.; Ruzicka, J. J.; Crozier, L. G.; Huff, D. D.; Brodeur, R. D.; Stewart, J. D.

10.1101/2023.08.11.553012 — systems biology — Posted on 2024-02-01

4506 DNA-Diffusion: Leveraging Generative Models for Controlling Chromatin Accessibility and Gene Expression via Synthetic Regulatory Elements

Ferreira DaSilva, L.; Senan, S.; Patel, Z. M.; Reddy, A. J.; Gabbita, S.; Nussbaum, Z.; Cordova, C. M. V.; Wenteler, A.; Weber, N.; Tunjic, T. M.; Khan, T. A.; Li, Z.; Smith, C. R.; Bejan, M.; Louis, L. K.; Cornejo, P.; Connell, W.; Wong, E. S.; Meuleman, W.; Pinello, L.

10.1101/2024.02.01.578352 — synthetic biology — Posted on 2024-02-01

4507 Ultra-sensitive water contaminant detection with transcription factor interfaced microcantilevers

Agarwal, D. K.; Lucci, T. J.; Jung, J. K.; Shekhawat, G. S.; Lucks, J. B.; Dravid, V. P. B.

10.1101/2024.02.01.578376 — synthetic biology — Posted on 2024-02-01

4508 Label-Free, Real-Time Monitoring of Cytochrome C Responses to Drugs in Microdissected Tumor Biopsies with a Multi-Well Aptasensor Platform

Nguyen, T. N. H.; Horowitz, L.; Krilov, T.; Lockhart, E.; Kenerson, H. L.; Yeung, R. S.; Arroyo-Curras, N.; Folch, A.

10.1101/2024.01.31.578278 — bioengineering — Posted on 2024-02-01

4509 Formulation, Characterization and Pharmacokinetic Evaluation of Amorphous Solid Dispersions of Glibenclamide for Bioavailability Enhancement in Wistar Rats

mir, K.; Khan, N.; Shah, M. U. D.; Dar, A. A.; na,

10.1101/2024.01.31.578259 — biochemistry — Posted on 2024-02-01

4510 Single-Stranded DNA with Internal Base Modifications Mediates Highly Efficient Gene Insertion in Primary Cells

Kanke, K. L.; Rayner, R. E.; Abel, E.; Venugopalan, A.; Suu, M.; Stack, J. T.; Nouri, R.; Guo, G.; Vetter, T. A.; Cormet-Boyaka, E.; Hester, M. E.; Vaidyanathan, S.

10.1101/2024.02.01.578476 — molecular biology — Posted on 2024-02-01

4511 Clostridioides difficile-mucus interactions encompass shifts in gene expression, metabolism, and biofilm formation

Furtado, K. L.; Plott, L. M.; Markovetz, M. R.; Powers, D. A.; Wang, H.; Hill, D. B.; Papin, J. A.; Allbritton, N. L.; Tamayo, R.

10.1101/2024.02.01.578425 — microbiology — Posted on 2024-02-01

4512 Expression of the locus of enterocyte effacement genes during the invasion process of the atypical enteropathogenic Escherichia coli 1711-4 strain of serotype O51:H40

Romao, F. T.; Santos, A. C. M.; Sperandio, V.; Hernandes, R. T.; Gomes, T. A. T.

10.1101/2024.02.01.578415 — microbiology — Posted on 2024-02-01

4513 Visualizing the impact of disease-associated mutations on G protein-nucleotide interactions

Anazia, K.; Koenekoop, L.; Ferre, G.; Petracco, E.; Gutierrez-de-Teran, H.; Eddy, M.

10.1101/2024.01.30.578006 — biophysics — Posted on 2024-02-01

4514 Helicase-assisted continuous editing for programmable mutagenesis of endogenous genomes

Chen, X. D.; Chen, Z.; Wythes, G.; Zhang, Y.; Orr, B. C.; Sun, G.; Thao, K.; Vallurupalli, M.; Sun, J.; Borji, M.; Tkacik, E.; Chen, H.; Bernstein, B. E.; Chen, F.

10.1101/2024.02.01.577593 — genetics — Posted on 2024-02-01

4515 EcoLiDAR: An economical LiDAR scanner for ecological research

Pereira Mendes, C.; Lim, N. T.-L.

10.1101/2024.01.31.578255 — ecology — Posted on 2024-02-01

4516 Bilateral regulation of EGFR activity and local PI dynamics observed with superresolution microscopy

Abe, M.; Yanagawa, M.; Hiroshima, M.; Kobayashi, T.; Sako, Y.

10.1101/2024.02.01.578337 — cell biology — Posted on 2024-02-01

4517 Mitochondrial Ca2+ efflux controls neuronal metabolism and long-term memory across species

Vishwanath, A. A.; Comyn, T.; Chintaluri, C.; Ramon-Duaso, C.; Fan, R.; Sivakumar, R.; Lopez-Manzaneda, M.; Preat, T.; Vogels, T. P.; Rangaraju, V.; Busquets-Garcia, A.; Placais, P.-Y.; Pavlowsky, A.; de Juan-Sanz, J.

10.1101/2024.02.01.578153 — neuroscience — Posted on 2024-02-01

4518 MicroRNAs and mRNA Regulatory Network of Parenchymal Hematoma after Endovascular Mechanical Reperfusion for Acute Ischemic Stroke in Rat

Zhuang, J.-K.; Huang, Z.-R.; Qin, W.; Li, C.-L.; Li, Q.; Xiang, C.; Tuo, Y.-H.; Liu, Z.; Chen, Q.-Y.; Shi, Z.-S.

10.1101/2024.02.01.578357 — neuroscience — Posted on 2024-02-01

4519 Systematic characterization of protein structural features of alternative splicing isoforms using AlphaFold 2

Yang, Y.; Xie, Y.; Li, Z.; Diala, C.; Ali, M.; Li, R.; Xu, Y.; Wu, A.; Kim, P.; Hosseini, S.-R.; Bi, E.; Zhao, H.; Zheng, W. J.

10.1101/2024.01.30.578053 — bioinformatics — Posted on 2024-02-01

4520 Reconstructing microvascular network skeletons from 3D images: what is the ground truth?

Walsh, C.; Berg, M.; West, H.; Holroyd, N. A.; Walker-Samuel, S.; Shipley, R. J.

10.1101/2024.02.01.578347 — bioengineering — Posted on 2024-02-01

4521 Collagen organization and structure in FLBN5-/- mice using label-free microscopy: implications for pelvic organ prolapse

Jennings, C.; Markel, A.; Domingo, M.; Miller, K.; Bayer, C.; Parekh, S. H.

10.1101/2024.01.31.578106 — bioengineering — Posted on 2024-02-01

4522 Generation and analysis of a mouse multi-tissue genome annotation atlas

Adams, M. S.; Vollmers, C.

10.1101/2024.01.31.578267 — genomics — Posted on 2024-02-01

4523 Trait prediction through computational intelligence and machine learning applied to soybean (Glycine max) breeding in shaded environments

da Silva Junior, A. C.; Costa, W. G. d.; Guimaraes, A. G.; Moura, W. M.; Bhering, L. L.; Cruz, C. D.; Batista, R. O.; Santos, J. B.; Campos, W. F.; Evaristo, A. B.

10.1101/2024.01.31.578252 — genetics — Posted on 2024-02-01

4524 Investigating low frequency somatic mutations in Arabidopsis with Duplex Sequencing

Waneka, G.; Pate, B.; Monroe, J. G. B.; Sloan, D. B.

10.1101/2024.01.31.578196 — genetics — Posted on 2024-02-01

4525 A simple, robust, broadly applicable insertion mutagenesis method to create random fluorescent protein - target protein fusions.

Pike, A.; Pietryski, C.; Deighan, P.; Kuehner, J. N.; Lau, D.; Seshan, A.; March, P. E.

10.1101/2024.01.30.578020 — genetics — Posted on 2024-02-01

4526 A gene-rich mitochondrion with a unique ancestral protein transport system

Moreira, D.; Blaz, J.; Kim, E.; Eme, L.

10.1101/2024.01.30.577968 — evolutionary biology — Posted on 2024-02-01

4527 Parallel evolution in mosquito vectors - a duplicated esterase locus is associated with resistance to pirimiphos-methyl in An. gambiae

Nagi, S. C.; Lucas, E. R.; Egyir-Yawson, A.; Essandoh, J.; Dadzie, S.; Chabi, J.; Djogbenou, L. S.; Medjigbodo, A. A.; Edi, C. V.; Ketoh, G.; Koudou, B. G.; Ashraf, F.; Clarkson, C. S.; Miles, A.; Weetman, D.; Donnelly, M. J.

10.1101/2024.02.01.578361 — evolutionary biology — Posted on 2024-02-01

4528 Distributional shifts change the biodiversity-ecosystem stability relationship under climate change

Kanamori, Y.; Nishijima, S.; Misawa, R.; Seto, T.; Narimatsu, Y.

10.1101/2024.01.31.578304 — ecology — Posted on 2024-02-01

4529 Environmental, host, and symbiont drivers of heat tolerance in a species complex of reef-building corals

Naugle, M. S.; Denis, H.; Mocellin, V. J. L.; Laffy, P. W.; Popovic, I.; Bay, L. K.; Howells, E. J.

10.1101/2024.01.31.575130 — ecology — Posted on 2024-02-01

4530 Landscape-scale spatial variations of pre-Columbian anthropogenic disturbances at three ring ditch sites in French Guiana

TESTE, M.; Engel, J.; Mabobet, K.; Mestre, M.; Brousseau, L.

10.1101/2024.01.31.578258 — ecology — Posted on 2024-02-01

4531 A range expanding ecosystem engineer influences historical and expanded habitats via the same causal pathways

Roy, M. S.; Johnson, D. S.; Byrnes, J. E. K.

10.1101/2024.01.31.578099 — ecology — Posted on 2024-02-01

4532 Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations

Khattar, Z.; Madrazo, N.; Powers, E.; Rosarda, J. D.; Wiseman, L.

10.1101/2024.01.30.577830 — cell biology — Posted on 2024-02-01

4533 Global Release of Translational Repression Across Plasmodiums Host-to-Vector Transmission Event

Rios, K. T.; McGee, J. P.; Sebastian, A.; Moritz, R. L.; Feric, M.; Absalon, S.; Swearingen, K. E.; Lindner, S. E.

10.1101/2024.02.01.577866 — microbiology — Posted on 2024-02-01

4534 Depth-dependent scaling of axial distances in light microscopy

Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.

10.1101/2024.01.31.578242 — biophysics — Posted on 2024-02-01

4535 LukProt: A database of eukaryotic predicted proteins designed for investigations of animal origins

Sobala, L. F.

10.1101/2024.01.30.577650 — bioinformatics — Posted on 2024-02-01

4536 Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes

Hu, K.; Meyer, F.; Deng, Z.-L.; Asgari, E.; Kuo, T.-H.; Münch, P. C.; McHardy, A. C.

10.1101/2024.01.31.578169 — bioinformatics — Posted on 2024-02-01

4537 Comprehensive genome annotation of the model ciliate Tetrahymena thermophila by in-depth epigenetic and transcriptomic profiling

Ye, F.; Chen, X.; Ju, A.; Sheng, Y.; Duan, L.; Al-Rasheid, K. A. S.; Stover, N. A.; Gao, S.

10.1101/2024.01.31.578305 — bioinformatics — Posted on 2024-02-01

4538 The domesticated transposon protein L1TD1 associates with its ancestor L1 ORF1p to promote LINE-1 retrotransposition

Kavaklioglu, G.; Podhornik, A.; Vcelkova, T.; Marjanovic, J.; Beck, M. A.; Mair, T.; Miccolo, C.; Drino, A.; Egger, G.; Chiocca, S.; Modic, M.; Seiser, C.

10.1101/2024.02.01.577722 — genetics — Posted on 2024-02-01

4539 Effects of water nutrient concentrations on stream macroinvertebrate community stoichiometry: a large-scale study

Beck, M.; Billoir, E.; Usseglio-Polatera, P.; Meyer, A.; Gautreau, E.; Danger, M.

10.1101/2024.02.01.574823 — ecology — Posted on 2024-02-01

4540 Glycan-induced structural activation softens the human papillomavirus capsid for entry through reduction of intercapsomere flexibility

Feng, Y.; van Bodegraven, D.; Kadek, A.; L.B. Munguira, I.; Soria-Martinez, L.; Nentwich, S.; Kavan, D.; Uetrecht, C.; Schelhaas, M.; Roos, W. H.

10.1101/2024.02.01.577804 — microbiology — Posted on 2024-02-01

4541 Synaptic plasticity in human thalamocortical assembloids

Patton, M. H.; Thomas, K. T.; Bayazitov, I. T.; Newman, K. D.; Kurtz, N. B.; Robinson, C. G.; Ramirez, C. A.; Trevisan, A. J.; Bikoff, J. B.; Peters, S. T.; Pruett-Miller, S. M.; Jiang, Y.; Schild, A. B.; Nityanandam, A.; Zakharenko, S. S.

10.1101/2024.02.01.578421 — neuroscience — Posted on 2024-02-01

4542 Chromatin remodeling protein CHD4 regulates axon guidance of spiral ganglion neurons in developing cochlea

Kim, J.; Martinez, E.; Qiu, J.; Ni, J. Z.; Kwan, K.

10.1101/2024.01.31.578202 — neuroscience — Posted on 2024-02-01

4543 1-Aminocyclopropane-1-carboxylic acid oxidase determines the fate of ethylene biosynthesis in a tissue-specific way to fine-tune development and stress resilience

Houben, M.; Vaughan-Hirsch, J.; Pattyn, J.; Mou, W.; Roden, S.; Martinez, A. R.; Kabak, E.; Rodrigues, S.; Polko, A.; De Coninck, B.; Kieber, J. J.; Voet, A. R.; Van de Poel, B.

10.1101/2024.02.01.578397 — plant biology — Posted on 2024-02-01

4544 Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma

Imle, R.; Blosel, D.; Kommoss, F.; Zhao, E.; Autry, R.; Blume, C.; Lupar, D.; Schmitt, L.; Winter, C.; Wagner, L.; Placke, S.; von Eicke, M.; Hertwig, M.; Peterziel, H.; Oehme, I.; Scheuerman, S.; Seitz, C.; Geyer, F.; Cidre-Aranaz, F.; Grunewald, T.; Vokuhl, C.; Chudasama, P.; Scholl, C.; Schmidt, C.; Gunther, P.; Sill, M.; Jones, K.; Pfister, S.; Banito, A.

10.1101/2024.01.30.577924 — cancer biology — Posted on 2024-02-01

4545 RNF43 is a gatekeeper for colitis-associated cancer

Dietl, A.; Ralser, A.; Taxauer, K.; Dregelies, T.; Sterlacci, W.; Stadler, M.; Olayo-Alarcon, R.; Margaryan, S.; Skerhut, M.; Groll, T.; Steiger, K.; Singh, D.; Li, X.; Oellinger, R.; Rad, R.; Janssen, K. P.; Mueller, C. L.; Vieth, M.; Gerhard, M.; Mejias Luque, R.

10.1101/2024.01.30.577936 — cancer biology — Posted on 2024-02-01

4546 Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients

Azimi, M.; Cho, S.; Bozkurt, E.; McDonough, E.; Kisakol, B.; Matveeva, A.; Salvucci, M.; Lindner, A.; Dussmann, H.; Shia, J.; McDade, S.; Longley, D. B.; Ginty, F.; Prehn, J. H. M.

10.1101/2024.01.30.577720 — cancer biology — Posted on 2024-02-01

4547 A shade-responsive microProtein in the Arabidopsis ATHB2 gene regulates elongation growth and root development

Edwards, A. K.; Chiurazzi, M. J.; Blaakmeer, A.; Vittozzi, Y.; Sharma, A.; Matton, S.; Kruusvee, V.; Straub, D.; Sessa, G.; Carabelli, M.; Morelli, G.; Wenkel, S.

10.1101/2024.02.01.578400 — plant biology — Posted on 2024-02-01

4548 Analysis arbuscular mycorrhizal fungi (AMF) community composition associated with alkaline saline sodic soils

Marquez, N.; Irazoqui, J. M.; Ciacci, M. B.; Amadio, A. F.; Fernandez, F. D.; Giachero, M. L.

10.1101/2024.02.01.578375 — plant biology — Posted on 2024-02-01

4549 In vivo targeted and deterministic single cell malignant transformation

Scerbo, P.; Tisserand, B.; Delagrange, M.; Debare, H.; Bensimon, D.; Ducos, B.

10.1101/2024.01.30.577941 — cancer biology — Posted on 2024-02-01

4550 Structurally-informed human interactome reveals proteome-wide perturbations by disease mutations

Xiong, D.; Qiu, Y.; Zhao, J.; Zhou, Y.; Lee, D.; Gupta, S.; Torres, M.; Lu, W.; Liang, S.; Kang, J. J.; Eng, C.; Loscalzo, J.; Cheng, F.; Yu, H.

10.1101/2023.04.24.538110 — bioinformatics — Posted on 2024-02-01

4551 Characteristics of vicarious touch reports in a general population

Smit, S.; Zopf, R.; Rich, A.

10.1101/2024.01.30.577948 — neuroscience — Posted on 2024-02-01

4552 The Circadian Neuropeptide PDF has Sexually Dimorphic Effects on Activity Rhythms

Iyer, A. R.; Scholz-Carlson, E.; Bell, E.; Biondi, G.; Richhariya, S.; Fernandez, M. d. l. P.

10.1101/2024.01.31.578273 — neuroscience — Posted on 2024-02-01

4553 Twilight length alters growth, flowering time, and clock function in Arabidopsis via LHY/CCA1

Mehta, D.; Scandola, S.; Kennedy, C.; Lummer, C.; Rodriguez Gallo, M. C.; Grubb, L. E.; Tan, M.; Scarpella, E.; Uhrig, R. G.

10.1101/2023.06.09.544111 — plant biology — Posted on 2024-02-01

4554 Cryo-EM structures of human cone visual pigments

Peng, Q.; Li, J.; Jiang, H.; Cheng, X.; Lu, Q.; Zhou, S.; Zhang, Y.; Lv, S.; Wan, S.; Yang, T.; Chen, Y.; Zhang, W.; Nan, W.; Che, T.; Li, Y.; Liao, H.; Zhang, J.

10.1101/2024.01.30.577689 — biophysics — Posted on 2024-02-01

4555 Bold zebrafish (danio rerio) learn faster in an associative learning task

Corcoran, J.; Storks, L.; Wong, R. Y.

10.1101/2024.01.30.578005 — animal behavior and cognition — Posted on 2024-02-01

4556 Estimating scale-specific and localized spatial patterns in allele frequency

Lasky, J. R.; Takou, M.; Gamba, D.; Keitt, T. H.

10.1101/2022.03.21.485229 — evolutionary biology — Posted on 2024-02-01

4557 Temporal variability in host availability alters the outcome of competition between two parasitoid species

Wang, H.; Liu, T.; Sun, S.; Lewis, O.; Xi, X.

10.1101/2024.01.30.577865 — ecology — Posted on 2024-02-01

4558 Simultaneous Identification of Changepoints and Model Parameters in Switching Dynamical Systems

Fu, X.; Fan, K.; Zozmann, H.; Schüler, L.; Calabrese, J.

10.1101/2024.01.30.577909 — ecology — Posted on 2024-02-01

4559 Age-related RPE Changes in Wildtype C57BL/6J Mice Between 2 and 32 Months

Shelton, D. A.; Gefke, I.; Liao, K.; Summers, V.; Yu, H.; Kim, Y.-K.; Getz, Y.; Ferdous, S.; Donaldson, K.; Papania, J.; Chrenek, M.; Boatright, J.; Nickerson, J.

10.1101/2024.01.30.574142 — cell biology — Posted on 2024-02-01

4560 Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

Contento, G.; Wilson, J.-A. A.; Selvarajah, B.; Plate, M.; Guillotin, D.; Morales, V.; Trevisani, M.; Pitozzi, V.; Bianchi, K.; Chambers, R. C.

10.1101/2024.01.30.577965 — cell biology — Posted on 2024-02-01

4561 Interplay between Two Paralogous Human Silencing Hub (HuSH) Complexes in Regulating LINE-1 Element Silencing

Jensvold, Z. D.; Christenson, A. E.; Flood, J. R.; Lewis, P. W.

10.1101/2023.12.28.573526 — molecular biology — Posted on 2024-02-01

4562 Chemokine expression profile of an innate granuloma

Amason, M. E.; Harvest, C. K.; Beatty, C. J.; Saban, D. R.; Miao, E. A.

10.1101/2024.01.30.577927 — immunology — Posted on 2024-02-01

4563 Mobile version of the Battery for the Assessment of Auditory Sensorimotor and Timing Abilities (BAASTA): Implementation and adult norms

Dalla Bella, S.; Foster, N.; Laflamme, H.; Zagala, A.; Kadi, M.; Komeilipoor, N.; Blais, M.; Rigoulot, S.; Kotz, S. A.

10.1101/2023.07.21.550031 — neuroscience — Posted on 2024-02-01

4564 Diffusion MRS tracks distinct trajectories of neuronal development in the cerebellum and thalamus of rat neonates.

Ligneul, C.; Qiu, L.; Clarke, W. T.; Jbabdi, S.; Palombo, M.; Lerch, J.

10.1101/2023.10.16.562599 — neuroscience — Posted on 2024-02-01

4565 The Constitutive Activity Of The Histamine H1 Receptor Interaction With The NMDA Receptor

Armand, V.; ARRANG, J. M.

10.1101/2021.11.02.466417 — neuroscience — Posted on 2024-02-01

4566 Transcriptome-wide quantitative profiling of PUS7-dependent pseudouridylation by nanopore direct long read RNA sequencing

Bansal, M.; Kundu, A.; Gibson, A.; Gupta, A.; Ding, J.; RudraRaju, S. V.; Sudarshan, S.; Ding, H.-F.

10.1101/2024.01.31.578250 — cancer biology — Posted on 2024-02-01

4567 Structural perspective on the design of selective DYRK1B inhibitors.

Grygier, P.; Pustelny, K.; Menezes, F.; Jemiola-Rzeminska, M.; Suder, P.; Dubin, G.; Czarna, A.

10.1101/2022.12.23.521429 — biochemistry — Posted on 2024-02-01

4568 Rapid QC-MS - Interactive Dashboard for Synchronous Mass Spectrometry Data Acquisition Quality Control

Sandhu, W.; Gray, I. J.; Lin, S.; Elias, J. E.; DeFelice, B. C.

10.1101/2024.01.30.578059 — biochemistry — Posted on 2024-02-01

4569 Non-autonomous cell redox-pairs dictate niche homeostasis in multi-lineage stem populations

Majhi, O.; Chhatre, A.; Chaudhary, T.; Sinha, D.

10.1101/2023.12.06.570086 — developmental biology — Posted on 2024-02-01

4570 CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization

Serbynovskyi, V.; Wang, J.; Chua, E. Y. D.; Ishemgulova, A.; Alink, L. M.; Budell, W. C.; Johnston, J. D.; Dubbeldam, C.; Gonzalez, F. A.; Rozovsky, S.; Eng, E. T.; de Marco, A.; Noble, A. J.

10.1101/2024.01.23.576763 — molecular biology — Posted on 2024-02-01

4571 What if...? The granular layer, the input layer of the cerebellar network: a theory

Gilbert, M.; Rasmussen, A.

10.1101/2023.07.14.548987 — neuroscience — Posted on 2024-02-01

4572 A single pair of pharyngeal neurons functions as a commander to reject high salt in Drosophila melanogaster

Sang, J.; Dhakal, S.; Shrestha, B.; Nath, D. K.; Kim, Y.; Ganguly, A.; Montell, C.; Lee, Y.

10.1101/2023.10.17.562703 — neuroscience — Posted on 2024-02-01

4573 Neural correlates of memory in a naturalistic spatiotemporal context

Dougherty, M. R.; Chang, W.; Rudoler, J. H.; Katerman, B. S.; Halpern, D.; Bruska, J. P.; Diamond, N.; Kahana, M. J.

10.1101/2022.11.30.518606 — neuroscience — Posted on 2024-02-01

4574 The landscape of glial pathology and T-call response in Parkinson's substantia nigra

Jakubiak, K.; Paryani, F.; Kannan, A.; Lee, J.; Madden, N.; Li, J.; Chen, D.; Mahajan, A.; Xia, S.; Flowers, X.; Menon, V.; Sulzer, D.; Goldman, J. E.; Sims, P. A.; Al-Dalahmah, O.

10.1101/2024.01.08.574736 — neuroscience — Posted on 2024-02-01

4575 A dendritic mechanism for balancing synaptic flexibility and stability

Yaeger, C. E.; Vardalaki, D.; Zhang, Q.; Pham, T. L. D.; Brown, N. J.; Ji, N.; Harnett, M. T.

10.1101/2022.02.02.478840 — neuroscience — Posted on 2024-02-01

4576 TCRfp: a new fingerprint-based approach for TCR repertoire analysis

Mayol-Rullan, F.; Bugnon, M.; Perez Gomes, M. A. S.; Zoete, V.

10.1101/2023.12.19.572261 — cancer biology — Posted on 2024-02-01

4577 Cholesterol-Dependent Membrane Deformation by Metastable Viral Capsids Facilitates Entry

Jiao, M.; Danthi, P.; Yu, Y.

10.1101/2024.01.10.575085 — biophysics — Posted on 2024-02-01

4578 MOSim: bulk and single-cell multi-layer regulatory network simulator

Monzo, C.; Arzalluz, A.; Martinez-Mira, C.; Conesa, A.; Tarazona, S.

10.1101/421834 — bioinformatics — Posted on 2024-02-01

4579 Fragment ion intensity prediction improves the identification rate of non-tryptic peptides in timsTOF

Adams, C.; Gabriel, W.; Laukens, K.; Picciani, M.; Wilhelm, M.; Bittremieux, W.; Boonen, K.

10.1101/2023.07.17.549401 — bioinformatics — Posted on 2024-02-01

4580 Ketone body 3-hydroxybutyrate alleviates CCl4-induced liver fibrosis in mice through regulation of mitochondrial fission and reduction of oxidative stress

Zhang, Y.; Liu, X.; Wang, Y.; Liu, M.; Guo, Z.; Zhang, J.; Wu, F.; Chen, G.

10.1101/2024.01.27.577553 — biochemistry — Posted on 2024-02-01

4581 Coexistence of self-compatible and self-incompatible alleles in a plant metapopulation via spatial rock-paper-scissors dynamics

Daniel, S.; Thattai, M.

10.1101/2024.01.31.578129 — ecology — Posted on 2024-02-01

4582 Cell-material interactions in 3D bioprinted plant cells

Madison, I.; Tahir, M. A.; Van den Broeck, L.; Phan, L.; Horn, T.; Sozzani, R.

10.1101/2024.01.30.578043 — cell biology — Posted on 2024-02-01

4583 The clouded mother-of-pearl Protogoniomorpha anacardii Linnaeus, 1758 (Lepidoptera: Nymphalidae) - an updated record of butterfly for Saudi Arabia

ALFAKIH, A.; AL FAIFY, E. A.

10.1101/2023.12.22.572884 — zoology — Posted on 2024-02-01

4584 Preference for Scientist Occupation Among Medical and Science Students in South Korea

Bae, E. B.

10.1101/2024.01.31.578132 — scientific communication and education — Posted on 2024-02-01

4585 Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity

Chhillar, H.; Yeh, P.-M.; Nguyen, H. H.; Jones, J. D.; Ding, P.

10.1101/2024.02.01.578334 — plant biology — Posted on 2024-02-01

4586 Identification of genes involved in Kranz anatomy evolution of non-model grasses using unsupervised machine learning

Prochetto, S.; Stegmayer, G.; Studer, A.; Reinheimer, R.

10.1101/2024.01.31.578221 — plant biology — Posted on 2024-02-01

4587 High density linkage to physical mapping in a unique Tall x Dwarf Coconut (Cocos nucifera L.) F2 population uncovers a major QTL for flowering time colocalized with the FLOWERING LOCUS T (FT)

Alves, W. B. d. S.; Pacheco, C. A. P.; Grattapaglia, D.

10.1101/2024.01.31.578260 — plant biology — Posted on 2024-02-01

4588 Receptor kinase LecRK-I.9 regulates cell wall remodelling and signalling during lateral root formation in Arabidopsis

Bellande, K.; Roujol, D.; Chourre, J.; Le Gall, S.; Martinez, Y.; Jauneau, A.; Burlat, V.; JAMET, E.; Canut, H.

10.1101/2024.01.31.578125 — plant biology — Posted on 2024-02-01

4589 SlWRKY80 recruits SlHDA1 to regulates the tomato fruit ripening and color transformation

Hu, X.; Shang, C.; Chen, G.; Liu, X.; zheng, H.; Li, G.; Wang, J.; Hu, S.; Li, Z.

10.1101/2024.01.31.578225 — plant biology — Posted on 2024-02-01

4590 Integrated GWAS and Transcriptomic Analysis Identify New Candidate Genes for Seminal Root Growth Angle in Wheat (Triticum aestivum L.)

Paez-Garcia, A.; de Bang, L.; Maulana, F.; Kwon, T.; Krom, N.; Kahn, R.; Ma, X.; Blancaflor, E. B.

10.1101/2024.01.31.578154 — plant biology — Posted on 2024-02-01

4591 Leveraging genomics and temporal high-throughput phenotyping to enhance association mapping and yield prediction in sesame

Sabag, I.; Bi, Y.; sahoo, M. M.; Herrmann, I.; Morota, G.; Peleg, Z.

10.1101/2024.02.01.578346 — plant biology — Posted on 2024-02-01

4592 WITHDRAWN: How antimicrobial heteroresistance promotes bacterial adaptation to antimicrobial therapy - or not

Liao, J.; Nyhoegen, C.; Uecker, H.; Schulenburg, H.

10.1101/2023.09.07.556728 — evolutionary biology — Posted on 2024-02-01

4593 Mutations in HUA2 restore flowering in the Arabidopsis trehalose 6-phosphate synthase1 (tps1) mutant

Zeng, L.; Zacharaki, V.; Wang, Y.; Schmid, M.

10.1101/2024.01.31.578264 — plant biology — Posted on 2024-02-01

4594 LazyAF, a pipeline for accessible medium-scale in silico prediction of protein-protein interactions

McLean, T. C.

10.1101/2024.01.29.577767 — bioinformatics — Posted on 2024-02-01

4595 ENT3C: an entropy-based similarity measure for contact matrices

Lainscsek, X.; Taher, L.

10.1101/2024.01.30.577923 — bioinformatics — Posted on 2024-02-01

4596 Sequence, Structure and Functional space of Drosophila de novo proteins

Middendorf, L.; Ravi Iyengar, B.; Eicholt, L. A.

10.1101/2024.01.30.577933 — bioinformatics — Posted on 2024-02-01

4597 PHACTboost: A Phylogeny-aware Boosting Algorithm to Compute the Pathogenicity of Missense Mutations

Dereli, O.; Kuru, N.; Akkoyun, E.; Bircan, A.; Tastan, O.; Adebali, O.

10.1101/2024.01.30.577938 — bioinformatics — Posted on 2024-02-01

4598 An analysis of semaphorin-mediated cellular interactions in the C. elegans epidermis using the IR-LEGO single-cell gene induction system

Suzuki, M.; Takagi, S.

10.1101/2024.01.24.577022 — developmental biology — Posted on 2024-02-01

4599 Targeting PD-L1 in solid cancer with myeloid cells expressing a CAR-like immune receptor

Chen, K. M.; Grun, D.; Gautier, B.; Venkatesha, S.; Maddox, M.; Zhang, A.-H.; Andersen, P.

10.1101/2024.01.29.577873 — immunology — Posted on 2024-02-01

4600 A multi-transcriptomics approach reveals the coordinated action of the endoribonuclease DNE1 and the decapping machinery in orchestrating mRNA decay

Pouclet, A.; Pflieger, D.; Merret, R.; Carpentier, M.-C.; Schiaffini, M.; Zuber, H.; Gagliardi, D.; Garcia, D.

10.1101/2024.01.31.578142 — plant biology — Posted on 2024-02-01

4601 Early body weight gain in TALLYHO/JngJ mice predicts adult diabetic phenotype, mimicking childhood obesity

Hastreiter, S.; Hoffmann, S.; Richter, K.; Irmler, M.; Gerlini, R.; Fuchs, H.; Gailus-Dumer, V.; Gailus-Durner, V.; Korner, A.; Hrabe de Angelis, M.; Beckers, J.

10.1101/2024.01.29.577705 — physiology — Posted on 2024-02-01

4602 Transcriptome-wide quantitative profiling of PUS7-dependent pseudouridylation by nanopore direct long read RNA sequencing

Bansal, M.; Kundu, A.; Gibson, A.; Gupta, A.; Ding, J.; RudraRaju, S. V.; Sudarshan, S.; Ding, H.-F.

10.1101/2024.01.31.578250 — cancer biology — Posted on 2024-02-01

4603 Accelerated Hematopoietic Stem Cell Aging in Space

Pham, J.; Isquith, J.; Balaian, L.; Ladel, L.; Nandi, S. P.; Mack, K.; van der Werf, I.; Klacking, E.; Ruiz, A.; Mays, D.; Gamble, P.; Giza, S.; Janowitz, J.; Nienaber, T.; Mishra, T.; Kulidjian, A.; Stoudemire, J.; Snyder, M. P.; Clements, T.; Muotri, A. R.; Morris, S. R.; Whisenant, T.; Alexandrov, L. B.; Jamieson, C. H. M.

10.1101/2024.01.28.577076 — cancer biology — Posted on 2024-02-01

4604 Deep co-learning on transcription factors and their binding regions attains impeccable universality in plants

Gupta, S.; Kesarwani, V.; Bhati, U.; Jyoti, ; Shankar, R.

10.1101/2023.11.16.567355 — bioinformatics — Posted on 2024-02-01

4605 Divergent Folding-Mediated Epistasis Among Unstable Membrane Protein Variants

Chamness, L. M.; Kuntz, C. P.; McKee, A. G.; Penn, W. D.; Hemmerich, C. M.; Rusch, D. B.; Woods, H.; Dyotima, ; Meiler, J.; Schlebach, J. P.

10.1101/2023.08.25.554866 — biochemistry — Posted on 2024-02-01

4606 A "torn bag mechanism" of small extracellular vesicle release via limiting membrane rupture of en bloc released amphisomes (amphiectosomes)

Visnovitz, T.; Lenzinger, D.; Koncz, A.; Vizi, P. M.; Barkai, T.; Vukman, K. V.; Galinsoga, A.; Nemeth, K.; Fletcher, K.; Komlosi, Z. I.; Lorincz, P.; Valcz, G.; BUZAS, E. I.

10.1101/2024.01.30.578035 — cell biology — Posted on 2024-02-01

4607 Average Nucleotide Identity based Staphylococcus aureus strain grouping allows identification of strain-specific genes in the pangenome

Raghuram, V.; Petit, R. A.; Karol, Z.; Mehta, R.; Weissman, D.; Read, T. D.

10.1101/2024.01.29.577756 — microbiology — Posted on 2024-02-01

4608 Microbiota encoded fatty-acid metabolism expands tuft cells to protect tissues homeostasis during Clostridioides difficile infection in the large intestine

Kellogg, T. D.; Ceglia, S.; Mortzfeld, B. M.; Zeamer, A. L.; Foley, S. E.; Ward, D.; Bhattarai, S. K.; McCormick, B. A.; Reboldi, A.; Bucci, V.

10.1101/2024.01.29.574039 — immunology — Posted on 2024-02-01

4609 Early life adversity drives sex-dependent changes in 5-mC DNA methylation of parvalbumin cells in the prefrontal cortex in rats

Noel, E. S.; Chen, A.; Pena, Y. A.; Honeycutt, J. A.

10.1101/2024.01.31.578313 — neuroscience — Posted on 2024-02-01

4610 Brain white matter pathways of resilience to chronic back pain: a multisite validation

Misic, M.; Lee, N.; Zidda, F.; Sohn, K.; Usai, K.; Löffler, M.; Uddin, N.; Farooqi, A.; Schifitto, G.; Zhang, Z.; Nees, F.; Geha, P.; Flor, H.

10.1101/2024.01.30.578024 — neuroscience — Posted on 2024-02-01

4611 Behavioural responses to acute warming precede critical shifts in the cellular and physiological thermal stress responses in fish

Durhack, T. C.; Thorstensen, M. J.; Mackey, T. E.; Aminot, M.; Lawrence, M. J.; Audet, C.; Enders, E. C.; Jeffries, K. M.

10.1101/2024.01.29.577477 — physiology — Posted on 2024-02-01

4612 Cooperativity of c-MYC with Krüppel-Like Factor 6 Splice Variant 1 induces phenotypic plasticity and promotes prostate cancer progression and metastasis

Izadmehr, S.; Fernandez-Hernandez, H.; Wiredja, D.; Kirschenbaum, A.; Lee-Poturalski, C.; Tavassoli, P.; Yao, S.; Schlatzer, D.; Hoon, D.; DiFeo, A.; Levine, A. C.; Mosquera, J.-M.; Galsky, M. D.; Cordon-Cardo, C.; Narla, G.

10.1101/2024.01.30.577982 — cancer biology — Posted on 2024-02-01

4613 Ensemble learning and ground-truth validation of synaptic connectivity inferred from spike trains

Donner, C.; Bartram, J.; Hornauer, P.; Kim, T.; Roqueiro, D.; Hierlemann, A.; Obozinski, G.; Schroeter, M.

10.1101/2024.02.01.578336 — neuroscience — Posted on 2024-02-01

4614 Multiplexing of temporal and spatial information in the lateral entorhinal cortex

Wang, C.; Lee, H.; Rao, G.; Knierim, J. J.

10.1101/2024.01.31.578307 — neuroscience — Posted on 2024-02-01

4615 Dissociating endogenous and exogenous delta activity during natural speech comprehension

Chalas, N.; Meyer, L.; Lo, C.-W.; Park, H.; Kluger, D. S.; Abbasi, O.; Kayser, C.; Nitsch, R.; Gross, J.

10.1101/2024.02.01.578181 — neuroscience — Posted on 2024-02-01

4616 Upregulated cholesterol biosynthesis facilitates the survival of methylation-retaining AML cells following decitabine treatment.

Bond, D. R.; Burnard, S. M.; Uddipto, K.; Hunt, K. V.; Harvey, B. M.; Steffens Reinhardt, L.; Lawlor-O'Neill, C.; Roper, E. A.; Humphries, S.; Murray, H. C.; Bowden, N. A.; Enjeti, A. K.; Verrills, N. M.; Riveros, C.; Le Cao, K.-A.; Lee, H. J.

10.1101/2024.01.30.577864 — cancer biology — Posted on 2024-02-01

4617 Discovery and Characterization of Terpene Synthases Powered by Machine Learning

Samusevich, R.; Hebra, T.; Bushuiev, R.; Bushuiev, A.; Chatpatanasiri, R.; Kulhanek, J.; Calounova, T.; Perkovic, M.; Engst, M.; Tajovska, A.; Sivic, J.; Pluskal, T.

10.1101/2024.01.29.577750 — biochemistry — Posted on 2024-02-01

4618 Cycling reduces the entropy of neuronal activity in the human adult cortex

Ferre, I. B. S.; Corso, G.; dos Santos Lima, G. Z.; Lopes, S. R.; Leocadio-Miguel, M. A.; Franca, L.; de Lima Prado, T.; Araujo, J. F.

10.1101/2024.01.31.578253 — neuroscience — Posted on 2024-02-01

4619 Generating synthetic signaling networks for in silico modeling studies

Xu, J.; Wiley, S.; Sauro, H. M.

10.1101/2020.05.08.084848 — systems biology — Posted on 2024-02-01

4620 Treacle's ability to form liquid phase condensates is essential for nucleolar fibrillar center assembly, efficient rRNA transcription and processing, and rRNA gene repair.

Velichko, A. K.; Kovina, A. P.; Luzhin, A. V.; Petrova, N. V.; Deriglazov, D. A.; Kazakov, E. P.; Kireev, I. I.; Razin, S. V.; Kantidze, O.

10.1101/2023.05.11.540311 — cell biology — Posted on 2024-02-01

4621 Developmental effect of RASopathy mutations on neuronal network activity on a chip

Weiss, E.-M.; Guhathakurta, D.; Petruskova, A.; Hundrup, V.; Zenker, M.; Fejtova, A.

10.1101/2023.09.20.558464 — neuroscience — Posted on 2024-02-01

4622 C4 Grasses Employ Distinct Strategies to Acclimate Rubisco Activase to Heat Stress

Stainbrook, S. C.; Aubuchon, L. N.; Chen, A.; Johnson, E.; Si, A.; Walton, L.; Ahrendt, A.; Strenkert, D.; Jez, J. M.

10.1101/2022.08.24.505184 — plant biology — Posted on 2024-02-01

4623 SSingle-molecule analysis reveals the phosphorylation of FLS2 regulates its spatiotemporal dynamics and immunity

Cui, Y.; Qian, H.; Yin, J.; Xu, C.; Luo, P.; Zhang, X.; Yu, M.; Su, B.; Li, X.; Lin, J.

10.1101/2023.08.22.553824 — plant biology — Posted on 2024-02-01

4624 Numerical and analytical simulation of the growth of amyloid-β plaques

Kuznetsov, A. V.

10.1101/2023.09.11.557187 — biophysics — Posted on 2024-02-01

4625 The Phage-shock-protein (PSP) Envelope Stress Response:Discovery of Novel Partners and Evolutionary History

Ravi, J.; Anantharaman, V.; Chen, S. Z.; Brenner, E. P.; Datta, P.; Aravind, L.; Gennaro, M. L.

10.1101/2020.09.24.301986 — bioinformatics — Posted on 2024-02-01

4626 TTSBBC: Triplex Target Site Biomarkers and Barcodes in Cancer

Ylagan, M.; Xu, Q.; Kowalski, J.

10.1101/2024.01.26.577471 — bioinformatics — Posted on 2024-02-01

4627 Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake

Yang, T.; Xiao, H.; Chen, X.; Zheng, L.; Guo, H.; Wang, J.; Jiang, X.; Zhang, C.-Y.; Yang, F.; Ji, X.

10.1101/2023.08.01.551569 — biochemistry — Posted on 2024-02-01

4628 Genetic similarity between relatives provides evidence on the presence and history of assortative mating

Sunde, H. F.; Eftedal, N. H.; Cheesman, R.; Corfield, E. C.; Kleppesto, T. H.; Seierstad, A. C.; Ystrom, E.; Eilertsen, E. M.; Torvik, F. A.

10.1101/2023.06.27.546663 — genetics — Posted on 2024-02-01

4629 Gelatinous matrix, an original convergent evolution to cope with oligotrophy in Nassellaria (Radiolaria)

Llopis Monferrer, N.; Romac, S.; Laget, M.; Biard, T.; Sandin, M. M.

10.1101/2024.01.22.576765 — evolutionary biology — Posted on 2024-02-01

4630 Recombination rate variation shapes genomic variability of phylogeographic structure in a widespread North American songbird (Aves: Certhia americana)

Manthey, J. D.; Spellman, G. M.

10.1101/2022.09.25.509431 — evolutionary biology — Posted on 2024-02-01

4631 Horizontally transferred cell-free chromatin particles function as miniature predatory genomes and vehicles for transposable elements within host cells

Banerjee, S.; Shende, S.; Lopes, R.; Praveen, S.; Joshi, R.; Kata, L.; Khare, N. K.; Gorantla, R.; Mittra, I.

10.1101/2023.11.21.567988 — evolutionary biology — Posted on 2024-02-01

4632 Spatial trajectories of coffee harvesting in large-scale plantations: ecological and management drivers and implications

Mora Van Cauwelaert, E.; Boyer, D.; Jimenez-Soto, E.; Gonzalez Gonzalez, C.; Benitez, M.

10.1101/2023.10.31.564942 — ecology — Posted on 2024-02-01

4633 A note on predator-prey dynamics in radiocarbon datasets

Marom, N.; Wolkowski, U.

10.1101/2023.11.12.566733 — ecology — Posted on 2024-02-01

4634 Rbm8a deficiency causes hematopoietic defects by modulating Wnt/PCP signaling

Kocere, A.; Chiavacci, E.; Soneson, C.; Wells, H. H.; Mendez-Acevedo, K. M.; MacGowan, J. S.; Jacobson, S. T.; Hiltabidle, M. S.; Raghunath, A.; Shavit, J. A.; Panakova, D.; Williams, M. L. K.; Robinson, M. D.; Mosimann, C.; Burger, A.

10.1101/2023.04.12.536513 — developmental biology — Posted on 2024-02-01

4635 Coupling and uncoupling of midline morphogenesis and cell flow in amniote gastrulation

Asai, R.; Prakash, V. N.; Sinha, S.; Prakash, M.; Mikawa, T.

10.1101/2023.05.26.542486 — developmental biology — Posted on 2024-02-01

4636 Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

Holman, C. D.; Sakers, A. P.; Calhoun, R. P.; Cheng, L.; Fein, E. C.; Jacobs, C.; Tsai, L.; Rosen, E. D.; Seale, P.

10.1101/2023.03.20.533514 — developmental biology — Posted on 2024-02-01

4637 Cell cycle variants during Drosophila accessory gland development

Box, A. M.; Ramesh, N. A.; Nandakumar, S.; Church, S. J.; Prasad, D.; Afrakhteh, A.; Taichman, R. S.; Buttitta, L.

10.1101/719013 — developmental biology — Posted on 2024-02-01

4638 Rediscovering the Rete Ovarii: a secreting auxiliary structure to the ovary

Anbarci, D. N.; McKey, J.; Levic, D. S.; Bagnat, M.; Capel, B.

10.1101/2023.11.08.566085 — developmental biology — Posted on 2024-02-01

4639 foxe1 mutant zebrafish show indications of a hypothyroid phenotype and increased sensitivity to ethanol for craniofacial malformations

Raterman, S. T.; Wagner, F. A. D. T. G.; Zethof, J.; Cuijpers, V.; Klaren, P. H. M.; Metz, J. R.; Von den Hoff, J. W.

10.1101/2024.01.31.578204 — developmental biology — Posted on 2024-02-01

4640 Hedgehog signaling is required for the maintenance of mesenchymal nephron progenitors

Chung, E.; Deacon, P.; Hu, Y.-C.; Lim, H.-W.; Park, J.-S.

10.1101/2023.08.12.553098 — developmental biology — Posted on 2024-02-01

4641 Low Shear in Short-Term Impacts Endothelial Cell Traction and Alignment in Long-Term

Chandurkar, M. K.; Mittal, N.; Royer-Weeden, S. P.; Lehmann, S. D.; Rho, Y.; Han, S. J.

10.1101/2023.09.20.558732 — cell biology — Posted on 2024-02-01

4642 Dynamic localization of the chromosomal passenger complex is controlled by the orphan kinesins KIN-A and KIN-B in the kinetoplastid parasite Trypanosoma brucei

Ballmer, D.; Akiyoshi, B.

10.1101/2023.10.11.561882 — cell biology — Posted on 2024-02-01

4643 Collaborative Cross mice have diverse phenotypic responses to infection with Methicillin-resistant Staphylococcus aureus USA300

Nagarajan, A.; Scoggin, K.; Gupta, J.; Aminian, M.; Adams, L. G.; Kirby, M.; threadgill, D.; Andrews-Polymenis, H. L.

10.1101/2023.07.12.548741 — microbiology — Posted on 2024-02-01

4644 Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples From Healthy Individuals

Chappell, C. L.; Hoffman, K. L.; Lorenzi, P. L.; Tan, L.; Petrosino, J.; Gibbs, R.; Muzny, D.; Doddapaneni, H.; Ross, M. C.; Menon, V. K.; Surathu, A.; Javornik Cregeen, S. J.; Reyes, A. G.; Okhuysen, P. C.

10.1101/2023.12.20.572622 — microbiology — Posted on 2024-02-01

4645 A transmission bottleneck for malaria? Quantification of sporozoite expelling by Anopheles mosquitoes infected with laboratory and naturally circulating P. falciparum gametocytes

10.1101/2023.08.03.551751 — microbiology — Posted on 2024-02-01

4646 Metabolic disruption impairs ribosomal protein levels, resulting in enhanced aminoglycoside tolerance

Shiraliyev, R. C.; Orman, M.

10.1101/2023.12.20.572673 — microbiology — Posted on 2024-02-01

4647 SAR324 and related lineages are associated with the evolutionary history and origins of dsr-mediated sulfur oxidation

Klier, K. M.; Martin, C.; Langwig, M. V.; Anantharaman, K.

10.1101/2024.01.30.576480 — microbiology — Posted on 2024-02-01

4648 Candida albicans' inorganic phosphate transport and evolutionary adaptation to phosphate scarcity

Acosta-Zaldivar, M.; Qi, W.; Mishra, A.; Roy, U.; King, W. R.; Patton-Vogt, J.; Anderson, M. Z.; Kohler, J. R.

10.1101/2024.01.29.577887 — microbiology — Posted on 2024-02-01

4649 Viral gene drive spread during herpes simplex virus 1 infection in mice

Walter, M.; Haick, A. K.; Riley, R.; Massa, P. A.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Aubert, M.; Taylor, M. P.; Jerome, K. R.; Verdin, E.

10.1101/2023.12.07.570711 — microbiology — Posted on 2024-02-01

4650 Transposable elements regulate thymus development and function

Larouche, J.-D.; Laumont, C. M.; Trofimov, A.; Vincent, K.; Hesnard, L.; Brochu, S.; Cote, C.; Humeau, J.; Bonneil, E.; Lanoix, J.; Durette, C.; Gendron, P.; Laverdure, J.-P.; Richie, E. R.; Lemieux, S.; Thibault, P.; Perreault, C.

10.1101/2023.07.12.548732 — immunology — Posted on 2024-02-01

4651 Sex differences in brain-behavior relationships in the first two years of life

Fenske, S. J.; Liu, J.; Chen, H.; Diniz, M.; Stephens, R.; Cornea, E.; Gilmore, J. H. J.; Gao, W.

10.1101/2024.01.31.578147 — neuroscience — Posted on 2024-02-01

4652 Functionally distinct subdomains of dopamine in the hippocampus

Mehra, M.; Molina, G. E.; Islam, M. T.; Dhanerawala, Z.; Bano, E.; Han, E.

10.1101/2024.01.31.578232 — neuroscience — Posted on 2024-02-01

4653 Exploring distinct and joint contributions of the Locus Coeruleus and the Substantia Nigra/Ventral Tegmental Area complex to reward and valence processing using high-resolution fMRI

Hall, J. M.; Shahnazian, D.; Krebs, R. M.

10.1101/2024.01.31.577328 — neuroscience — Posted on 2024-02-01

4654 Electrophysiological responses to syntactic and 'morphological' structures: evidence from Mandarin Chinese

Yu, X.; Tian, X.; Lau, E.

10.1101/2024.01.31.578104 — neuroscience — Posted on 2024-02-01

4655 Cortical acetylcholine dynamics are predicted by cholinergic axon activity and behavior state

Neyhart, E.; Zhou, N.; Munn, B. R.; Law, R. G.; Smith, C.; Mridha, Z. H.; Blanco, F. A.; Li, G.; Li, Y.; McGinley, M. J.; Shine, J. M.; Reimer, J.

10.1101/2023.11.14.567116 — neuroscience — Posted on 2024-02-01

4656 Octopamine integrates the status of internal energy supply into the formation of food-related memories

Berger, M.; Auweiler, K.; Tegtmeier, M. F.; Dorn, K.; El Khadrawe, T.; Scholz, H.

10.1101/2023.06.01.543187 — neuroscience — Posted on 2024-02-01

4657 ARX regulates interneuron subtype differentiation and migration

Cho, G.; Lim, Y.; Akula, S. K.; Myers, A. K.; Chen, C.; Rafael, K.; Walsh, C. A.; Golden, J. A.

10.1101/2024.01.31.578282 — neuroscience — Posted on 2024-02-01

4658 Functional connectivity favors aberrant visual network c-Fos expression accompanied by cortical synapse loss in amyloidosis.

L'esperance, O. J.; McGhee, J.; Davidson, G.; Smith, A. S.; Niraula, S.; Subramanian, J.

10.1101/2023.01.05.522900 — neuroscience — Posted on 2024-02-01

4659 Building compositional tasks with shared neural subspaces

Tafazoli, S.; Bouchacourt, F.; Ardalan, A.; Markov, N. T.; Uchimura, M.; Gomes Mattar, M. G.; Daw, N. D.; Buschman, T. J.

10.1101/2024.01.31.578263 — neuroscience — Posted on 2024-02-01

4660 Using normative models pre-trained on cross-sectional data to evaluate longitudinal changes in neuroimaging data

Rehak Buckova, B.; Fraza, C.; Rehak, R.; Kolenic, M.; Beckmann, C.; Spaniel, F.; Marquand, A.; Hlinka, J.

10.1101/2023.06.09.544217 — neuroscience — Posted on 2024-02-01

4661 Distributed fMRI dynamics predict distinct EEG rhythms across sleep and wakefulness

Jacob, L. P. L.; Bailes, S. M.; Williams, S. D.; Stringer, C.; Lewis, L. D.

10.1101/2024.01.29.577429 — neuroscience — Posted on 2024-02-01

4662 The Intricate Relationship of G-Quadruplexes and Bacterial Pathogenicity Islands

Lyu, B.; Song, Q.

10.1101/2023.07.06.548048 — pathology — Posted on 2024-02-01

4663 Interlimb coordination in Parkinson's disease is minimally affected by a visuospatial dual task

Hill, A.; Nantel, J.

10.1101/2022.07.15.500215 — pathology — Posted on 2024-02-01

4664 Laminin-defined Mechanical Status Modulates Retinal Pigment Epithelium Functionality

Kozyrina, A. N.; Piskova, T.; Semeraro, F.; Doolaar, I.; Prapty, T.; Haraszti, T.; Hubert, M.; Windoffer, R.; Leube, R. E.; Smith, A.-S.; Di Russo, J.

10.1101/2023.02.24.529913 — biophysics — Posted on 2024-02-01

4665 CpG Island Definition and Methylation Mapping of the T2T-YAO Genome

Xiao, M.; Wei, R.; Yu, J.; Gao, C.; Yang, F.; Zhang, L.

10.1101/2023.12.02.568720 — bioinformatics — Posted on 2024-02-01

4666 ProteinMPNN Recovers Complex Sequence Properties of Transmembrane β-Barrels

Dolorfino, M. D.; Samanta, R.; Vorobieva, A. A.

10.1101/2024.01.16.575764 — bioinformatics — Posted on 2024-02-01

4667 Structural mechanisms for VMAT2 inhibition by tetrabenazine

Dalton, M. P.; Cheng, M. H.; Bahar, I.; Coleman, J. A.

10.1101/2023.09.05.556211 — biochemistry — Posted on 2024-02-01

4668 Sex-dependent effects of Setd1a haploinsufficiency on development and adult behaviour

Bosworth, M. L.; Isles, A. R.; Wilkinson, L. S.; Humby, T.

10.1101/2024.01.31.578257 — animal behavior and cognition — Posted on 2024-02-01

4669 Computational basis of hierarchical and counterfactual information processing

Ramadan, M.; Tang, C.; Watters, N.; Jazayeri, M.

10.1101/2024.01.30.578076 — neuroscience — Posted on 2024-02-01

Archive, 2024-02