bioRxiv directory

1 Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in African American and European American patients with TNBC

Zhu, Q.; Balasubramanian, A.; Asirvatham, J. R.; Piyarathna, D. W. B.; Kaur, J.; Mohamed, N.; Wu, L.; Chatterjee, M.; Wang, S.; Pourfarrokh, N.; Rasaily, U.; Xu, Y.; Zheng, J.; Jebakumar, D.; Rao, A.; Chen, S.-h.; Li, Y.; Chang, E.; Li, X.; Aneja, R.; Zhang, X. H.- F.; Sreekumar, A.

10.1101/2024.03.17.585428 — cancer biology — Posted on 2024-03-31

2 The critical role of isomiRs in accurate differential expression analysis of miRNA-seq data

Schmauch, E.; Attia, Y.; Laitinen, P.; Turunen, T. A.; Bartos, P.; Vaananen, M.-A.; Malm, T.; Tavi, P.; Kellis, M.; Kaikkonen, M. U.; Linna-Kuosmanen, S.

10.1101/2024.03.28.587190 — bioinformatics — Posted on 2024-03-31

3 Loci associated with cave-derived traits concentrate in specific regions of the Mexican cavefish genome

Wiese, J.; Richards, E. J.; Kowalko, J. E.; McGaugh, S. E.

10.1101/2024.03.29.587360 — evolutionary biology — Posted on 2024-03-31

4 An Assumption of The Regulatory Function of Nf2-Amot Complex in Early Mammalian Embryos with A Computational Model

Sakai, Y.; Hakura, J.

10.1101/2024.03.31.587462 — developmental biology — Posted on 2024-03-31

5 Baseline microbiome composition impacts resilience to and recovery following antibiotics

Chen, C.-Y.; Loeber, U.; Bartolomaeus, H.; Maier, L.; Muller, D. N.; Wilck, N.; Jarquin-Diaz, V. H.; Forslund-Startceva, S. K.

10.1101/2024.03.31.587491 — microbiology — Posted on 2024-03-31

6 Phenotypic characterization of HAM1, a novel mating regulator of the fungal pathogen Cryptococcus neoformans

Arsenault-Yee, E.; Ross, R. L.; Santiago-Tirado, F. H.

10.1101/2023.09.18.558251 — microbiology — Posted on 2024-03-31

7 Vitamin C prevents S. aureus infections of endothelial cells through its interaction with specific residues in the active site of gC1qR/p33 involved in direct entry, notably SER230, ASN345, ILE348, TYR224, ASN346, SER347, and GLU438, and its potential inhibitory effects on FnBPs, α5β1, and Protein A molecules

Miliani, M.; Hadjidj, Z.; Bensefia, Z.; Dahou, S.; Ammouche, N.; Hamdoun, I.; Benammar, H.; Benammar, S.; Aribi, M.

10.1101/2024.03.27.586894 — immunology — Posted on 2024-03-31

8 Control of behavioral uncertainty by divergent frontal circuits

Wang, Y.; Sun, Q.-Q.

10.1101/2024.03.29.587380 — neuroscience — Posted on 2024-03-31

9 Maternal Aggression Driven by the Transient Mobilization of a Dormant Hormone-Sensitive Circuit

Stagkourakis, S.; Williams, P.; Spigolon, G.; Khanal, S.; Ziegler, K.; Heikkinen, L.; Fisone, G.; Broberger, C.

10.1101/2023.02.02.526862 — neuroscience — Posted on 2024-03-31

10 A brain-to-text framework of decoding natural tonal sentences

Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Lu, J.

10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-31

11 Interleukin-1α links peripheral CaV2.2 channel activation to rapid adaptive increases in heat sensitivity in skin

Salib, A.-M. N.; Crane, M. J.; Lee, S. H.; Wainger, B. J.; Jamieson, A. M.; Lipscombe, D.

10.1101/2023.12.17.572072 — neuroscience — Posted on 2024-03-31

12 Alignment of auditory artificial networks with massive individual fMRI brain data leadsto generalizable improvements in brain encoding and downstream tasks

Freteault, M.; Le Clei, M.; Tetrel, L.; Bellec, P.; Farrugia, N.

10.1101/2023.09.06.556533 — neuroscience — Posted on 2024-03-31

13 Characterizing the expression patterns of short-day flowering genes, the manipulation of their expression using red-far red wavelengths, and the resulting phenotype/ chemotype in Cannabis sativa.

Haiden, S.

10.1101/2024.03.28.587211 — plant biology — Posted on 2024-03-31

14 Comparing cell penetration of biotherapeutics across human cell lines

Batistatou, N.; Kritzer, J.

10.1101/2024.03.28.587257 — pharmacology and toxicology — Posted on 2024-03-31

15 Nucleic Acid Aptamers Protect Against Lead (Pb(II)) Toxicity

Anwar, A.; Ramis De Ayreflor Reyes, S.; John, A. A.; Breiling, E.; O'Connor, A. M.; Reis, S.; Shim, J.-H.; Shah, A. A.; Srinivasan, J.; Farny, N. G.

10.1101/2024.03.28.587288 — pharmacology and toxicology — Posted on 2024-03-31

16 Integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits.

Okamoto, J.; Yin, X.; Ryan, B.; Chiou, J.; Luca, F.; Pique-Regi, R.; Im, H. K.; Morrison, J.; Burant, C.; Fauman, E.; Laakso, M.; Boehnke, M.; Wen, X.

10.1101/2024.03.28.587202 — bioinformatics — Posted on 2024-03-31

17 moPepGen: Rapid and Comprehensive Proteoform Identification

Zhu, C.; Liu, L. Y.; Yamaguchi, T. N.; Zhu, H.; Hugh-White, R.; Livingstone, J.; Patel, Y.; Kislinger, T.; Boutros, P. C.

10.1101/2024.03.28.587261 — bioinformatics — Posted on 2024-03-31

18 TemBERTure: Advancing protein thermostability prediction with Deep Learning and attention mechanisms

Rodella, C.; Lazaridi, S.; Lemmin, T.

10.1101/2024.03.28.587204 — bioinformatics — Posted on 2024-03-31

19 PREDICT: Advancing Accurate Gene Expression Prediction and Motif Identification in Plant Stress Responses

Wu, T.-Y.; Liu, M.-J.; Thalimaraw, L.; Eo, W. X. H.

10.1101/2024.03.28.587275 — bioinformatics — Posted on 2024-03-31

20 Assessing Heterogeneity in the N-Telopeptides of Type I Collagen by Mass Spectrometry

Darula, Z.; McCabe, M. C.; Barrett, A.; Schmitt, L. R.; Maslanka, M. D.; Saviola, A. J.; Orgel, J.; Burlingame, A.; Staab-Weijnitz, C. A.; Stenmark, K.; Weaver, V.; Chalkley, R. J.; Hansen, K. C.

10.1101/2024.03.31.587441 — biochemistry — Posted on 2024-03-31

21 Long-Read Structural and Epigenetic Profiling of a Kidney Tumor-matched Sample with Nanopore Sequencing and Optical Genome Mapping

Margalit, S.; Tulpova, Z.; Detinis Zur, T.; Michaeli, Y.; Deek, J.; Nifker, G.; Haldar, R.; Gnatek, Y.; Omer, D.; Dekel, B.; Grunwald, A.; Ebenstein, Y.

10.1101/2024.03.31.587463 — genomics — Posted on 2024-03-31

22 Phylogeography of the Giant Honeybees Based on Mitochondrial Gene Sequences

Bhatta, C. P.; Cluff, S. C.; Smith, D. R.

10.1101/2024.03.30.587434 — genetics — Posted on 2024-03-31

23 The Drosophila EcR-Hippo component Taiman promotes epithelial cell fitness by control of the Dally-like glypican and Wg gradient

Schweibenz, C. K.; Placentra, V.; Moberg, K.

10.1101/2024.03.31.587486 — developmental biology — Posted on 2024-03-31

24 Dynamics of MicroRNA Secreted via Extracellular Vesicles During the Maturation of Embryonic Stem Cell-Derived Retinal Pigment Epithelium

Lee, S. Y.

10.1101/2024.03.31.587478 — molecular biology — Posted on 2024-03-31

25 Essential genes for Haemophilus parainfluenzae survival and biofilm growth

de Palma, T. H.; Powers, C.; McPartland, M. J.; Welch, J. L. M.; Ramsey, M. M.

10.1101/2024.03.31.587483 — microbiology — Posted on 2024-03-31

26 3D Printers in Hospitals: Bacterial Contamination of Common and Antimicrobial 3D-Printed Material

Jackson, K. C.; Clancey, E.; Call, D.; Lofgren, E.

10.1101/2024.03.30.587440 — microbiology — Posted on 2024-03-31

27 TET2 regulates early and late transitions in exhausted CD8+ T-cell differentiation and limits CAR T-cell function

Dimitri, A. J.; Baxter, A. E.; Chen, G. M.; Hopkins, C. R.; Rouin, G. T.; Huang, H.; Kong, W.; Holliday, C. H.; Wiebking, V.; Bartoszek, R.; Drury, S.; Dalton, K.; Koucky, O. M.; Chen, Z.; Giles, J. R.; Jung, I.-Y.; O'Connor, R.; Collins, S.; Everett, J. K.; Amses, K.; Sherrill-Mix, S.; Chandra, A.; Goldman, N.; Vahedi, G.; Jadlowsky, J. K.; Young, R. M.; Melenhorst, J. J.; Maude, S. L.; Levine, B. L.; Frey, N. V.; Berger, S. L.; Grupp, S. A.; Porter, D. L.; Herbst, F.; Porteus, M. H.; Bushman, F. D.; Weber, E. W.; Wherry, E. J.; Jordan, M. S.; Fraietta, J. A.

10.1101/2024.03.29.587004 — immunology — Posted on 2024-03-31

28 IL-10 dependent adaptation allows macrophages to adjust inflammatory responses to TLR4 stimulation history

Bongartz, H.; Bradfield, C. J.; Gross, J. L.; Fraser, I.; Nita-Lazar, A.; Meier-Schellersheim, M.

10.1101/2024.03.28.587272 — immunology — Posted on 2024-03-31

29 Whole-Brain Dynamics Disruptions in the Progression of Alzheimer's Disease: Understanding the Influence of Amyloid-Beta and Tau

Patow, G. A.; Escrichs, A.; Ritter, P.; Deco, G.

10.1101/2024.03.29.587333 — neuroscience — Posted on 2024-03-31

30 Dendrite injury, but not axon injury, triggers neuroprotection in Drosophila models of neurodegenerative disease.

Prange, S. E.; Bhakta, I. N.; Sysoeva, D.; Jean, G. E.-H.; Madisetti, A.; Duong, L. U.; Hwu, P. T.; Melton, J. G.; Le, H. H. N.; Thompson-Peer, K. L.

10.1101/2024.03.29.587363 — neuroscience — Posted on 2024-03-31

31 The psychedelic, DOI, increases dopamine release in nucleus accumbens to predictable rewards and reward cues

Martin, D. A.; Delgado, A.; Calu, D. J.

10.1101/2024.03.29.587390 — neuroscience — Posted on 2024-03-31

32 Deep convolutional neural network with face identity recognition experience exhibits brain-like neural representations of personality traits

Li, W.; Li, J.; Jiang, T.

10.1101/2024.03.28.587135 — neuroscience — Posted on 2024-03-31

33 Neurofilament accumulation disrupts autophagy in giant axonal neuropathy

Paumier, J.-M.; Zewe, J.; Pergande, M. R.; Venkatesan, M.; Israeli, E.; Panja, C.; Snider, N.; Savas, J.; Opal, P.

10.1101/2024.03.29.587353 — neuroscience — Posted on 2024-03-31

34 Decoding Arc Transcription: A Live-Cell Study of Stimulation Patterns and Transcriptional Output

Kim, D. W.; Moon, H. C.; Lee, B. H.; Park, H. Y.

10.1101/2024.03.28.587245 — neuroscience — Posted on 2024-03-31

35 Multiple molecular links between the circadian clock and memory centers in honey bees

Roy, T.; Jain, R.; Brockmann, A.

10.1101/2024.03.31.587450 — neuroscience — Posted on 2024-03-31

36 Foraging Under Uncertainty Follows the Marginal Value Theorem with Bayesian Updating of Environment Representations

Webb, J.; Steffan, P.; Hayden, B. Y.; Lee, D.; Kemere, C.; McGinley, M.

10.1101/2024.03.30.587253 — neuroscience — Posted on 2024-03-31

37 LRRK2 kinase inhibition protects against Parkinson's disease-associated environmental toxicants

Ilieva, N. M.; Hoffman, E. K.; Ghalib, M. A.; Greenamyre, J. T.; De Miranda, B. R.

10.1101/2024.03.29.587369 — neuroscience — Posted on 2024-03-31

38 Enhancing Prediction of Human Traits and Behaviors through Ensemble Learning of Traditional and Novel Resting-State fMRI Connectivity Analyses

Yoshimoto, T.; Tokunaga, K.; Chikazoe, J.

10.1101/2024.03.30.587447 — neuroscience — Posted on 2024-03-31

39 Motion vision is tuned to maximize sensorimotor energy transfer in blowfly flight

Humbert, S.; Krapp, H. G.; Baeder, J. D.; Badrya, C.; Dawson, I. L.; Huang, J. V.; Hyslop, A.; Jung, Y. S.; Lutkus, C.; Mortimer, B.; Nagesh, I.; Ruah, C.; Walker, S. M.; Yang, Y.; Zbikowski, R.; Taylor, G. K.

10.1101/2024.03.29.587347 — neuroscience — Posted on 2024-03-31

40 Trauma Under Psychedelics: MDMA Shows Protective Effects During the Peritraumatic Period

Netzer, O.; Magal, N.; Stern, Y.; Polinsky, T.; Gross, R.; Admon, R.; Salomon, R.

10.1101/2024.03.28.587237 — neuroscience — Posted on 2024-03-31

41 Efficient Simulation of Viral Transduction and Propagation for Biomanufacturing

Destro, F.; Braatz, R. D.

10.1101/2024.03.30.587435 — synthetic biology — Posted on 2024-03-31

42 Description of new mandibular remains of Microcolobus from Nakali (ca. 10 Ma, Kenya): implications on the evolution of Miocene colobines.

Pallas, L.; Nakatsukasa, M.; Kunimatsu, Y.

10.1101/2024.03.31.587461 — paleontology — Posted on 2024-03-31

43 The TTLL10 polyglycylase is stimulated by tubulin glutamylation and inhibited by polyglycylation

Cummings, S.; Li, Y.; Spector, J.; Kim, C.; Roll-Mecak, A.

10.1101/2024.03.31.587457 — biochemistry — Posted on 2024-03-31

44 Characterizing medaka visual features using a high-throughput optomotor response assay

Suzuki, R.; Woo, J. Z.; Thumberger, T.; Hofmann, G.; Wittbrodt, J.; Tavhelidse, T.

10.1101/2024.03.28.587314 — animal behavior and cognition — Posted on 2024-03-31

45 Inhibition of striatal indirect pathway during second postnatal week leads to long lasting deficits in motivated behavior

Olivetti, P. R.; Torres-Herraez, A.; Raudales, R.; Sumerau, M. E.; Moyles, S.; Balsam, P.; Kellendonk, C.

10.1101/2024.03.29.586960 — animal behavior and cognition — Posted on 2024-03-31

46 Desynchronization between timers provokes transient arrest during C. elegans development

Romero-Exposito, F. J.; Moreno-Rivero, A.; Munoz-Barrera, M.; Garcia-Sanchez, S.; Rodriguez-Peris, F.; Gritti, N.; Sartor, F.; Merrow, M.; van Zon, J. S.; Mata-Cabana, A.; Olmedo, M.

10.1101/2024.03.31.587169 — developmental biology — Posted on 2024-03-31

47 Relationships between balance performance and connectivity of motor cortex with primary somatosensory cortex and cerebellum in middle aged and older adults

Sansare, A. A.; Magalhaes, T.; Bernard, J. A.

10.1101/2024.03.29.587335 — neuroscience — Posted on 2024-03-31

48 Target location and age-related dynamics affect conjunction visual search dynamics

Akbari, F.; Asivandzadehchaharmahali, S.; Narmashiri, A.

10.1101/2024.03.28.587192 — neuroscience — Posted on 2024-03-31

49 Carbon dioxide shapes parasite-host interactions in a human-infective nematode

Banerjee, N.; Gang, S. S.; Castelletto, M. L.; Ruiz, F.; Hallem, E. A.

10.1101/2024.03.28.587273 — neuroscience — Posted on 2024-03-31

50 An Open Resource: MR and light sheet microscopy stereotaxic atlas of the mouse brain

Mansour, H.; Azrak, R.; Cook, J. J.; Hornburg, K. J.; Qi, Y.; Tian, Y.; Williams, R. W.; Yeh, F.-C.; White, L. E.; Johnson, G. A.

10.1101/2024.03.28.587246 — neuroscience — Posted on 2024-03-31

51 Mu Suppression During Action Observation Only in the Lower, not in the Higher, Frequency Subband

Badakul, A. N.; Soyman, E.

10.1101/2024.03.28.587150 — neuroscience — Posted on 2024-03-31

52 TDP43 proteinopathy exhibits disease, tissue, and context-specific cryptic splicing signatures

Newton, D. F.; Yang, R.; Gutierrez, J.; Hofmann, J. W.; Yeh, F. L.; Biever, A.; Friedman, B. A.

10.1101/2024.03.29.587244 — neuroscience — Posted on 2024-03-31

53 Synaptic-dependent developmental dysconnectivity in 22q11.2 deletion syndrome

Alvino, F.-G.; Gini, S.; Minetti, A.; Pagani, M.; Sastre-Yague, D.; Barsotti, N.; De Guzman, E.; Schleifer, C.; Stuefer, A.; Kushan, L.; Montani, C.; Galbusera, A.; Papaleo, F.; Lombardo, M.-V.; Pasqualetti, M.; Bearden, C. E.; Gozzi, A.

10.1101/2024.03.29.587339 — neuroscience — Posted on 2024-03-31

54 fMROI: a simple and adaptable toolbox for easy region-of-interest creation

Peres, A. S. C.; Valerio, D.; Vaz, I. S.; Mahdiani, M.; Walbrin, J.; Almeida, J.

10.1101/2024.03.29.587330 — neuroscience — Posted on 2024-03-31

55 The subcommissural organ regulates brain development via secreted peptides

Zhang, T.; Ai, D.; Wei, P.; Xu, Y.; Bi, Z.; Ma, F.; Li, F.; Chen, X.-j.; Zhang, Z.; Zou, X.; Guo, Z.; Zhao, Y.; Li, J.-L.; Ye, M.; Feng, Z.; Zhang, X.; Zheng, L.; Yu, J.; Li, C.; Tu, T.; Zeng, H.; Lei, J.; Zhang, H.; Hong, T.; Zhang, L.; Luo, B.; Li, Z.; Xing, C.; Jia, C.; Li, L.; Sun, W.; Ge, W.-p.

10.1101/2024.03.30.587415 — neuroscience — Posted on 2024-03-31

56 Open-source, high performance miniature multiphoton microscopy systems for freely behaving animals

Madruga, B. A.; Dorian, C. C.; Sehgal, M.; Silva, A. J.; Shtrahman, M.; Aharoni, D.; Golshani, P.

10.1101/2024.03.29.586663 — neuroscience — Posted on 2024-03-31

57 Shape dynamics and migration of branched cells on complex networks

Liu, J.; Boix-Campos, J.; Ron, J. E.; Kux, J. M.; Gov, N.; Saez, P. J.

10.1101/2024.03.29.585638 — biophysics — Posted on 2024-03-31

58 CDHu40: a novel marker gene set of neuroendocrine prostate cancer (NEPC)

Liu, S.; Nam, H. S.; Zeng, Z.; Deng, X.; Pashaei, E.; Zang, Y.; Yang, L.; Li, C.; Huang, J.; Wendt, M. K.; Lu, X.; Huang, R.; Wan, J.

10.1101/2024.03.28.587205 — bioinformatics — Posted on 2024-03-31

59 Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking

el Azhar, Y.; Schulthess, P.; van Oostrom, M. J.; Meijer, W. H. M.; Thomas, W. M.; Bauer, M.; Sonnen, K. F.

10.1101/2024.03.30.586691 — developmental biology — Posted on 2024-03-31

60 Growth patterns of caudal fin rays are informed by both external signals from the regenerating organ and remembered identity autonomous to the local tissue

Autumn, M.; Hu, Y.; Zeng, J.; McMenamin, S.

10.1101/2024.03.29.586899 — developmental biology — Posted on 2024-03-31

61 The Colorado potato beetle gene expression atlas

Wilhelm, L.; Wang, Y.; Xu, S.

10.1101/2024.03.28.587222 — genomics — Posted on 2024-03-31

62 A pangenomic perspective of the Lake Malawi cichlid radiation reveals extensive structural variation driven by transposable elements

Quah, F. X.; Almeida, M. V.; Blumer, M.; Yuan, C. U.; Fischer, B.; See, K.; Jackson, B.; Zatta, R.; Rusuwa, B.; Turner, G. F.; Santos, M. E.; Svardal, H.; Hemberg, M.; Durbin, R.; Miska, E.

10.1101/2024.03.28.587230 — evolutionary biology — Posted on 2024-03-31

63 A Synergistic Desmin-SPARC Axis Regulates Cardiac Stem Cell Differentiation and Promotes Cardiomyogenesis through Autocrine Regulation

Leitner, L.; Schultheis, M.; Hofstetter, F.; Rudolf, C.; Kizner, V.; Fiedler, K.; Konrad, M.-T.; Hoebaus, J.; Genini, M.; Kober, J.; Ableitner, E.; Gmaschitz, T.; Walder, D.; Weitzer, G.

10.1101/2024.03.28.587296 — developmental biology — Posted on 2024-03-31

64 Enhanced NK cell proficiency in solid tumors through antigen-specific memory via NKG2C/A-HLA-E/ABC recruited to tumors by CXCR2

Sun, Y.; Furones, A. R.; Gultekin, O.; Khare, S.; Neo, S. Y.; Shi, W.; Galceran, L. M.; Lam, K.-P.; DasGupta, R.; Fuxe, J.; Salehi, S.; Lehti, K.; Sarhan, D.

10.1101/2024.03.28.585607 — immunology — Posted on 2024-03-31

65 Type I interferon drives a cellular state inert to TCR-stimulation and could impede effective T-cell differentiation in cancer

Corvino, D.; Batstone, M.; Hughes, B. G. M.; Kempchen, T.; Ng, S. S.; Salim, N.; Schneppenheim, F.; Rommel, D.; Kumar, A.; Pearson, S.; Madore, J.; Koufariotis, L. T.; Steinheuer, L. M.; Pathirana, D.; Thurley, K.; Hoelzel, M.; Borcherding, N.; Braun, M.; Bald, T.

10.1101/2024.03.28.587179 — immunology — Posted on 2024-03-31

66 The metabolic cofactor Coenzyme A enhances alternative macrophage activation via MyD88-linked signaling

Jones, A. E.; Rios, A.; Ibrahimovic, N.; Chavez, C.; Bayley, N. A.; Ball, A. B.; Hsieh, W. Y.; Sammarco, A.; Bianchi, A. R.; Cortez, A. A.; Graeber, T. G.; Hoffmann, A.; Bensinger, S. J.; Divakaruni, A. S.

10.1101/2024.03.28.587096 — immunology — Posted on 2024-03-31

67 Unveiling Frequency-Specific Microstate Correlates of Anxiety and Depression Symptoms

Xue, S.; Shen, X.; Zhang, D.; Sang, Z.; Long, Q.; Song, S.; Wu, J.

10.1101/2024.03.28.587119 — neuroscience — Posted on 2024-03-31

68 Human stem cell transplantation for Parkinson's disease: A systematic review of in situ survival and maturation of progenitors derived from human embryonic or induced stem cells in Parkinsonian models.

Comini, G.; Dowd, E.

10.1101/2024.03.28.587203 — neuroscience — Posted on 2024-03-31

69 Communication of perceptual predictions from the hippocampus to the deep layers of the parahippocampal cortex

Warrington, O.; Graedel, N. N.; Callaghan, M. F.; Kok, P.

10.1101/2024.03.28.587186 — neuroscience — Posted on 2024-03-31

70 Soft skeletons transmit force with variable gearing

Ellers, O.; Ellers, K.-I.; Johnson, A. S.; Po, T.; Heydari, S.; Kanso, E.; McHenry, M. J.

10.1101/2024.03.28.587271 — zoology — Posted on 2024-03-31

71 Expanding the use of reindeer foetal bone measurements for zooarchaeological applications

Discamps, E.; Soulier, M.-C.

10.1101/2024.03.28.587213 — zoology — Posted on 2024-03-31

72 Stacking haplotypes from the Vavilov wheat collection to accelerate breeding for multiple disease resistance

Tong, J.; Tarekegn, Z.; Alahmad, S.; Hickey, L.; Periyannan, S.; Dinglasan, E.; Hayes, B. J. A.

10.1101/2024.03.28.587294 — plant biology — Posted on 2024-03-31

73 The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of the glucocorticoid receptor in muscle.

Prabakaran, A. D.; Chung, H.-J.; McFarland, K.; Govindarajan, T.; Soussi, F. E. A.; Durumutla, H. B.; Villa, C.; Piczer, K.; Latimer, H.; Werbrich, C.; Akinborewa, O.; Horning, R.; Quattrocelli, M.

10.1101/2024.03.28.586997 — physiology — Posted on 2024-03-31

74 Establishing the foundations for a data-centric AI approach for virtual drug screening through a systematic assessment of the properties of chemical data

Chong, A.; Phua, S.-X.; Xiao, Y.; Ng, W. Y.; Li, H. Y.; Goh, W. W. B.

10.1101/2024.03.28.587184 — cancer biology — Posted on 2024-03-31

75 Development of a Two-Leaf Photosynthetic Model Sensitive to Chlorophyll and Its Coupling with a Wheat Growth Model

Tang, Y.; Wang, J.; Hong, Y.; Guo, C.; Zheng, H.; Yao, X.; Cheng, T.; Zhu, Y.; Cao, W.; Tian, Y.

10.1101/2024.03.28.587183 — biophysics — Posted on 2024-03-31

76 TraitProtNet: Deciphering the Genome for Trait Prediction with Interpretable Deep Learning

Wang, S.

10.1101/2024.03.28.587180 — bioinformatics — Posted on 2024-03-31

77 Overwintering performance of juvenile temperate estuarine fish

Bellotto, C.; Booth, D. J.; Fowler, A. M.

10.1101/2024.03.28.587281 — ecology — Posted on 2024-03-31

78 Current forest carbon offset buffer pools do not adequately insure against disturbance-driven carbon losses

Anderegg, W. R. L.; Trugman, A. T.; Vargas G., G.; Wu, C.; Yang, L.

10.1101/2024.03.28.587000 — ecology — Posted on 2024-03-31

79 Biomechanical regulation of cell shapes promotes branching morphogenesis of the ureteric bud epithelium

Kurtzeborn, K.; Iaroshenko, V.; Zarybnicky, T.; Koivula, J.; Anttonen, H. S.; Bridgewater, D.; Krishnan, R.; Chen, P.; Kuure, S.

10.1101/2024.03.28.585666 — developmental biology — Posted on 2024-03-31

80 Positional information modulates transient regeneration-activated cell states during vertebrate appendage regeneration.

Ortega Granillo, A.; Zamora, D.; Schnittker, R. R.; Scott, A. R.; Russell, J.; Brewster, C. E.; Ross, E. J.; Acheampong, D. A.; Ferro, K.; Morrison, J. A.; Rubinstein, B. Y.; Perera, A. G.; Wei, W.; Sanchez Alvarado, A.

10.1101/2024.03.28.587250 — developmental biology — Posted on 2024-03-31

81 A brain-to-text framework of decoding natural tonal sentences

Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Lu, J.

10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-31

82 Symmetry in levels of axon-axon homophilic adhesion establishes topography in the corpus callosum and development of connectivity between brain hemispheres

Poulopoulos, A.; Davis, P.; Brandenburg, C.; Itoh, Y.; Galazo, M. J.; Greig, L. C.; Romanowski, A. J.; Budnik, B.; Macklis, J. D.

10.1101/2024.03.28.587108 — neuroscience — Posted on 2024-03-31

83 Preservation of an Aging-Associated Mitochondrial Signature in Advanced Human Neuronal Models

Varghese, N.; Szabo, L.; Cader, Z.; Lejri, I.; Grimm, A.; Eckert, A.

10.1101/2024.03.28.587193 — neuroscience — Posted on 2024-03-31

84 GABAergic synapses between auditory efferent neurons and type II spiral ganglion afferent neurons in the mouse cochlea

Bachman, J. L.; Kitcher, S. R.; Vattino, L. G.; Beaulac, H. J.; Chaves, M. G.; Hernandez Rivera, I.; Katz, E.; Wedemeyer, C.; Weisz, C. J. C.

10.1101/2024.03.28.587185 — neuroscience — Posted on 2024-03-31

85 Powerful and accurate detection of temporal gene expression patterns from multi-sample multi-stage single cell transcriptomics data with TDEseq

Fan, Y.; Li, L.; Sun, S.

10.1101/2023.09.12.557282 — genomics — Posted on 2024-03-31

86 Unraveling the Evolutionary Trajectory of LHCI in Red-Lineage Algae: Conservation, Diversification, and Neolocalization

Kumazawa, M.; Ifuku, K.

10.1101/2024.03.16.585336 — evolutionary biology — Posted on 2024-03-31

87 Life history traits influence the dynamics of genetic diversityin a refugium population undergoing expansion andcontraction

Vishwakarma, R.; Sgarlata, G. M.; Soriano-Panos, D.; Rasteiro, R.; Maie, T.; Paixao, T.; Tournebize, R.; Chikhi, L.

10.1101/2024.03.28.586951 — evolutionary biology — Posted on 2024-03-31

88 Imaging of existing and newly translated proteins elucidates mechanisms of sarcomere turnover

Douvdevany, G.; Erlich, I.; Haimovich-Caspi, L.; Mashiah, T.; Prondzynski, M.; Pricolo, M. R.; Alegre-Cebollada, J.; Linke, W. A.; Carrier, L.; Kehat, I.

10.1101/2023.08.31.555653 — cell biology — Posted on 2024-03-31

89 Ribosomal Protein SA (RPSA) is required for localized translation and sarcomere maintenance in mice

Haddad, R.; Sadeh, O.; Ziv, T.; Erlich, I.; Haimovich-Caspi, L.; Shemesh, A.; van der Velden, J.; Kehat, I.

10.1101/2023.07.26.550187 — cell biology — Posted on 2024-03-31

90 Metabolic modeling reveals the aging-associated decline of host-microbiome metabolic interactions in mice

Best, L.; Dost, T.; Esser, D.; Flor, S.; Haase, M.; Kadibalban, A. S.; Marinos, G.; Walker, A.; Zimmermann, J.; Simon, R.; Schmidt, S.; Taubenheim, J.; Kunzel, S.; Hasler, R.; Groth, M.; Waschina, S.; Witte, O. W.; Schmitt-Kopplin, P.; Baines, J. F.; Frahm, C.; Kaleta, C.

10.1101/2024.03.28.587009 — systems biology — Posted on 2024-03-31

91 DNA Methylation (DM) data format and DMtools for efficient DNA methylation data storage and analysis

Zhou, Q.; Zhou, C.; Zhu, Z.; Sun, Y.; Li, G.

10.1101/2023.11.27.568779 — bioinformatics — Posted on 2024-03-30

92 Developmentally unique cerebellar processing prioritizes self- over other-generated movements

Richardson, A. M.; Sokoloff, G.; Blumberg, M. S.

10.1101/2023.12.16.571990 — neuroscience — Posted on 2024-03-30

93 Have AI-Generated Texts from LLM Infiltrated the Realm of Scientific Writing? A Large-Scale Analysis of Preprint Platforms

Cheng, H.; Sheng, B.; Lee, A.; Chaudhary, V.; Atanasov, A. G.; Liu, N.; Qiu, Y.; Wong, T. Y.; Tham, Y.-C.; Zheng, Y.-F.

10.1101/2024.03.25.586710 — scientific communication and education — Posted on 2024-03-30

94 Alternative splicing plays a nonredundant role in greater amberjack (Seriola dumerili) in the adaptation to ambient salinity fluctuations

Zhao, C.; Liu, Y.; Zhang, P.; Xia, X.; Yang, Y.

10.1101/2024.01.03.574042 — bioinformatics — Posted on 2024-03-30

95 Learning and actioning general principles of cancer cell drug sensitivity

Carli, F.; Di Chiaro, P.; Morelli, M.; Arora, C.; Bisceglia, L.; De Oliveira Rosa, N.; Cortesi, A.; Franceschi, S.; Lessi, F.; Di Stefano, A. L.; Santonocito, O. S.; Pasqualetti, F.; Aretini, P.; Miglionico, P.; Diaferia, G. R.; Giannotti, F.; Lio, P.; Duran-Frigola, M.; Mazzanti, C. M.; Natoli, G.; Raimondi, F.

10.1101/2024.03.28.586783 — bioinformatics — Posted on 2024-03-30

96 Marsilea: An intuitive generalized visualization paradigm for complex datasets

Zheng, Y.; Zheng, Z.; Rendeiro, A. F.; Cheung, E.

10.1101/2024.02.14.580236 — bioinformatics — Posted on 2024-03-30

97 Evaluation of Plant- and Microbial-Derived Protein Hydrolysates as Substitutes for Fetal Bovine Serum in Cultivated Seafood Cell Culture Media

Amirvaresi, A.; Ovissipour, R.

10.1101/2024.03.27.587063 — bioengineering — Posted on 2024-03-30

98 A new QRS detector stress test combining temporal jitter and F-score (JF) reveals significant performance differences amongst popular detectors

Porr, B.; Macfarlane, P. W.

10.1101/722397 — bioengineering — Posted on 2024-03-30

99 Single-cell genomics and regulatory networks for 388 human brains

Emani, P. S.; Liu, J. J.; Clarke, D.; Jensen, M.; Warrell, J.; Gupta, C.; Meng, R.; Lee, C. Y.; Xu, S.; Dursun, C.; Lou, S.; Chen, Y.; Chu, Z.; Galeev, T.; Hwang, A.; Li, Y.; Ni, P.; Zhou, X.; PsychENCODE Consortium, ; Bakken, T. E.; Bendl, J.; Bicks, L.; Chatterjee, T.; Cheng, L.; Cheng, Y.; Dai, Y.; Duan, Z.; Flaherty, M.; Fullard, J. F.; Gancz, M.; Garrido-Martin, D.; Gaynor-Gillett, S.; Grundman, J.; Hawken, N.; Henry, E.; Hoffman, G. E.; Huang, A.; Jiang, Y.; Jin, T.; Jorstad, N. L.; Kawaguchi, R.; Khullar, S.; Liu, J.; Liu, J.; Liu, S.; Ma, S.; Margolis, M.; Mazariegos, S.; Moore, J.; M

10.1101/2024.03.18.585576 — genomics — Posted on 2024-03-30

100 A spectral framework to map QTLs affecting joint differential networks of gene co-expression

Hu, J.; Weber, J. N.; Fuess, L. E.; Steinel, N. C.; Bolnick, D. I.; Wang, M.

10.1101/2024.03.29.587398 — genetics — Posted on 2024-03-30

101 Diel Partitioning in Microbial Phosphorus Acquisition in the Sargasso Sea

Muratore, D. J.; Gilbert, N. E.; LeCleir, G. R.; Wilhelm, S.; Weitz, J. S.

10.1101/2024.03.28.587236 — ecology — Posted on 2024-03-30

102 WEE1 inhibition triggers severe chromosome pulverization in aneuploid cells

Haykal, M. M.; Rodrigues-Ferreira, S.; Nahmias, C.

10.1101/2023.09.19.558475 — cell biology — Posted on 2024-03-30

103 Phylogenetic diversity of the carbon monoxide-utilizing prokaryotes and their divergent carbon monoxide metabolisms in the human gut microbiome

Katayama, Y. A.; Kamikawa, R.; Yoshida, T.

10.1101/2023.10.23.563559 — microbiology — Posted on 2024-03-30

104 Tools for Cre-mediated conditional deletion of floxed alleles from developing cerebellar Purkinje cells

Jahncke, J. N.; Wright, K. M.

10.1101/2024.03.28.587263 — neuroscience — Posted on 2024-03-30

105 How distinct sources of nuisance variability in natural images and scenes limit human stereopsis

White, D. N.; Burge, J.

10.1101/2024.02.27.582383 — neuroscience — Posted on 2024-03-30

106 Enhanced prefrontal nicotinic signaling as evidence of active compensation in Alzheimer's disease models

Power, S. K.; Venkatesan, S.; Qu, S.; McLaurin, J.; Lambe, E. K.

10.1101/2023.11.09.566499 — neuroscience — Posted on 2024-03-30

107 Phenylketonuria: modelling cerebral amino acid and neurotransmitter metabolism

Wegrzyn, A. B.; van Vliet, D.; van Eunen, K.; Heiner-Fokkema, M. R.; van der Zee, E. A.; van Spronsen, F.; Bakker, B. M.

10.1101/2024.01.05.574352 — systems biology — Posted on 2024-03-30

108 Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.

10.1101/2023.10.24.563805 — cancer biology — Posted on 2024-03-30

109 Tumor Stroma Content Regulates Penetration and Efficacy of Tumor-targeting Bacteria

Zhan, Y.; Burkel, B.; Leaman, E. J.; Ponik, S. M.; Behkam, B.

10.1101/2024.03.29.587035 — biophysics — Posted on 2024-03-30

110 Detection of known and novel virus sequences in the black solider fly and expression of host antiviral pathways

Walt, H. K.; Jordan, H. R.; Meyer, F.; Hoffmann, F. G.

10.1101/2024.03.29.587392 — bioinformatics — Posted on 2024-03-30

111 Sensitive Fluorescent Biosensor Reveals Differential Subcellular Regulation of PKC

Su, Q.; Zhang, J.; Lin, W.; Zhang, J.-f.; Newton, A. C.; Mehta, S.; Yang, J.; Zhang, J.

10.1101/2024.03.29.587373 — bioengineering — Posted on 2024-03-30

112 Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

Michael, A. R. M.; Amaral, B. C.; Ball, K. L.; Eiriksson, K. H.; Schriemer, D. C.

10.1101/2024.03.29.587383 — biochemistry — Posted on 2024-03-30

113 WHOLE GENOME TARGETED ENRICHMENT AND SEQUENCING OF HUMAN-INFECTING CRYPTOSPORIDIUM spp.

Bayona Vasquez, N. J.; Sullivan, A. H.; Beaudry, M. S.; Khan, A.; de Paula Baptista, R.; Petersen, K. N.; Bhuiyan, M. I. U.; Brunelle, B.; Robinson, G.; Chalmers, R. M.; Alves-Ferreira, E. V.; Grigg, M. E.; Kissinger, J. C.; Glenn, T. C.

10.1101/2024.03.29.586458 — genomics — Posted on 2024-03-30

114 CHANGE-seq-BE enables simultaneously sensitive and unbiased in vitro profiling of base editor genome-wide activity

Lazzarotto, C.; Katta, V.; Li, Y.; Urbina, E.; Lee, G.; Tsai, S. Q.

10.1101/2024.03.28.586621 — genomics — Posted on 2024-03-30

115 Long term co-circulation of multiple arboviruses in southeast Australia revealed by xeno-monitoring of mosquitoes and metatranscriptomics

Vieira, C. J. S. P.; Onn, M. B.; Shivas, M. A.; Shearman, D.; Darbro, J. M.; Graham, M.; Freitas, L.; van den Hurk, A. F.; Frentiu, F. F.; Wallau, G. L.; Devine, G. J.

10.1101/2024.03.29.587110 — genomics — Posted on 2024-03-30

116 CRISPR/Cas9 gene editing in Drosophila via visual selection in a summer classroom

Kockel, L.; Zhang, V.; Wang, J.; Gulick, C.; Laws, M. E.; Rajan, A.; Lantz, N.; Asgarova, A.; Dai, L.; Garcia, K.; Kim, C.; Li, M.; Ordonez-Acosta, P.; Peng, D.; Shull, H.; Tse, L.; Wang, Y.; Yu, W.; Zhou, Z.; Rankin, A.; Park, S.; Kim, S. K.

10.1101/2024.03.28.587232 — genetics — Posted on 2024-03-30

117 The Evolution of Microbiome-Mediated Traits

Week, B.; Morris, A. H.; Bohannan, B. J. M.

10.1101/2024.03.29.587374 — evolutionary biology — Posted on 2024-03-30

118 A next generation of hierarchical Bayesian analyses of hybrid zones enables direct quantification of variation in introgression in R

Gompert, Z.; DeRaad, D. A.; Buerkle, C. A.

10.1101/2024.03.29.587395 — evolutionary biology — Posted on 2024-03-30

119 Multispecies interactions and the community context of the evolution of virulence

Evensen, C.; White, A.; Boots, M.

10.1101/2024.03.29.587402 — evolutionary biology — Posted on 2024-03-30

120 Million years old recombination suppression and balancing selection in a region linked to the mating-type locus in the invasive chestnut blight fungal pathogen Cryphonectria parasitica

Hartmann, F. E.; Rodriguez de la Vega, R. C.; Rougemont, Q.; Demene, A.; Badet, T.; Croll, D.; Labat, A.; Prospero, S.; Snirc, A.; Stauber, L.; Dutech, C.; Giraud, T.

10.1101/2024.03.29.587348 — evolutionary biology — Posted on 2024-03-30

121 Timing of standard chow exposure determines the variability of mouse phenotypic outcomes and gut microbiota profile

Knuth, M. M.; Campos, C. V.; Smith, K.; Hutchins, E. K.; Lewis, S.; York, M.; Coghill, L. M.; Franklin, C.; MacFarlane, A.; Ericsson, A. C.; Magnuson, T.; Ideraabdullah, F.

10.1101/2024.03.28.587032 — developmental biology — Posted on 2024-03-30

122 A Genome-wide CRISPR screen unveils WDR91 protein as a promoter of productive ASO activity

Menchon, G.; Gaci, A.; Matvere, A.; Aubry, M.; Bore, A.; Goyenvalle, A.; Pedeux, R.

10.1101/2024.03.29.587208 — molecular biology — Posted on 2024-03-30

123 GTRpmix: A linked general-time reversible model for profile mixture models

Banos, H.; Wong, T. K. F.; Daneau, J.; Susko, E.; Minh, B. Q.; Lanfear, R.; Brown, M. W.; Eme, L.; Roger, A. J.

10.1101/2024.03.29.587376 — molecular biology — Posted on 2024-03-30

124 Identification of a proteolysis regulator for an essential enzyme in Mycobacterium tuberculosis

Kahne, S. C.; Yoo, J. H.; Chen, J.; Nakedi, K.; Iyer, L. M.; Putzel, G.; Samhadaneh, N. M.; Pironti, A.; Aravind, L.; Ekiert, D. C.; Bhabha, G.; Rhee, K. Y.; Darwin, K. H.

10.1101/2024.03.29.587195 — microbiology — Posted on 2024-03-30

125 Prophages express a type IV pilus component to provide anti-phage defence

Sztanko, K. M.; Javorcik, P. N.; Fitzpatrick, A. D.; Lenskaia, T.; Maxwell, K. L.; Davidson, A. R.

10.1101/2024.03.29.587342 — microbiology — Posted on 2024-03-30

126 A comprehensive two-hybrid analysis to explore the L. pneumophila effector-effector interactome

O'Connor Mount, H.; Urbanus, M. L.; Sheykhkarimli, D.; Cote, A. G.; Laval, F.; Coppin, G.; Kishore, N.; Li, R.; Spirohn-Fitzgerald, K.; Petersen, M. O.; Knapp, J. J.; Kim, D.-K.; Twizere, J.-C.; Calderwood, M. A.; Vidal, M.; Roth, F. P.; Ensminger, A. W.

10.1101/2024.03.29.587239 — microbiology — Posted on 2024-03-30

127 Novel extracellular matrix architecture on excitatory neurons revealed by HaloTag-HAPLN1

Sterin, I.; Niazi, A.; Kim, J.; Park, J.; Park, S.

10.1101/2024.03.29.587384 — neuroscience — Posted on 2024-03-30

128 GABAergic interneurons contribute to the fatal seizure phenotype of CLN2 disease mice

Takahashi, K.; Rensing, N. R.; Eultgen, E. M.; Wang, S. H.; Nelvagal, H. R.; Le, S. Q.; Roberts, M. S.; Doray, B.; Han, E.; Dickson, P.; Wong, M.; Sands, M. S.; Cooper, J. D.

10.1101/2024.03.29.587276 — neuroscience — Posted on 2024-03-30

129 p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

Luo, J.; Chen, Z.; Qiao, Y.; Tien, J. C.-Y.; Young, E.; Mannan, R.; Mahapatra, S.; He, T.; Eyunni, S.; Zhang, Y.; Zheng, Y.; Su, F.; Cao, X.; Wang, R.; Cheng, Y.; Seri, R.; George, J.; Shahine, M.; Miner, S. J.; Vaishampayan, U.; Wang, M.; Wang, S.; Parolia, A.; Chinnaiyan, A. M.

10.1101/2024.03.29.587346 — cancer biology — Posted on 2024-03-30

130 IL-8 Instructs Macrophage Identity in Lateral Ventricle Contacting Glioblastoma

Medina, S.; Brockman, A. A.; Cross, C. E.; Hayes, M. J.; Mobley, B. C.; Mistry, A. M.; Chotai, S.; Weaver, K. D.; Thompson, R.; Chambless, L. B.; Ihrie, R. A.; Irish, J. M.

10.1101/2024.03.29.587030 — cancer biology — Posted on 2024-03-30

131 Exploring protein-mediated compaction of DNA by coarse-grained simulations and unsupervised learning

de Jager, M.; Kolbeck, P. J.; Vanderlinden, W.; Lipfert, J.; Filion, L.

10.1101/2024.03.28.587201 — biophysics — Posted on 2024-03-30

132 Molecular determinants of Neu5Ac binding to tripartite ATP independent periplasmic (TRAP) transporter

Goyal, P.; Dhanabalan, K.; Scalise, M.; Friemann, R.; Indiveri, C.; Dobson, R. C.; Vinothkumar, K. R.; Subramanian, R.

10.1101/2024.03.29.587382 — biochemistry — Posted on 2024-03-30

133 Ribonuclease Inhibitor and Angiogenin collaboratively regulate cell-type-specific global translation

Stillinovic, M.; Sarangdhar, M. A.; Andina, N.; Tardivel, A.; Greub, F.; Bombaci, G.; Ansermet, C.; Heller, M.; Keogh, A.; Keller, I.; Angelillo-Scherrer, A.; Allam, R.

10.1101/2024.03.29.586999 — biochemistry — Posted on 2024-03-30

134 Cis-vaccenic acid is a key product of stearoyl-CoA desaturase 1 and a critical oncogenic factor in prostate cancer

Scott, J. S.; Young, R. S.; Quek, L.-E.; Miller, D. C.; Evergren, E. S.; Dehairs, J.; Johnson, I. R.; Brooks, D. A.; Loda, M.; Hoy, A. J.; Blanksby, S. J.; Swinnen, J. V.; Nassar, Z. D.; Butler, L. M.

10.1101/2024.03.28.587238 — cell biology — Posted on 2024-03-30

135 Investigating endometriosis development and endometriosis-related pain over time and in relation to estrogen in a laparoscopic mouse model

Peterse, D.; Verhassel, A.; Fassbender, A.; O, D. F.; Vanhie, A.; Van Rompuy, A.-S.; Saunders, P.; Vriens, J.; D'Hooghe, T.

10.1101/2024.03.28.583957 — cell biology — Posted on 2024-03-30

136 A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival

cassano, j.; Poolsup, S.; Duran, J.; Allers, l.; Leums, M.; cheng, q.; Salemi, M.; Phinney, B.

10.1101/2024.03.29.587368 — cell biology — Posted on 2024-03-30

137 Mesenchymal Stromal Cell Senescence Induced by Dnmt3a-Mutant Hematopoietic Cells is a Targetable Mechanism Driving Clonal Hematopoiesis and Initiation of Hematologic Malignancy

Mistry, J. J.; Young, K. A.; Diaz, P. C.; Maestre, I. F.; Levine, R.; Trowbridge, J. J.

10.1101/2024.03.28.587254 — cell biology — Posted on 2024-03-30

138 Co-Essentiality Analysis Identifies PRR12 as a Regulator of Cohesin and Genome Integrity

Nguyen, A. L.; Smith, E. M.; Cheeseman, I. M.

10.1101/2024.03.29.587394 — cell biology — Posted on 2024-03-30

139 Mesolimbic dopamine ramps reflect environmental timescales

Floeder, J. R.; Jeong, H.; Mohebi, A.; K Namboodiri, V. M.

10.1101/2024.03.27.587103 — neuroscience — Posted on 2024-03-30

140 Cell viscosity influences hematogenous dissemination and metastatic extravasation of tumor cells

Gensbittel, V.; Follain, G.; Bochler, L.; Uhlmann, K.; Lefebvre, O.; Larnicol, A.; Harlepp, S.; Goswami, R.; Girardo, S.; Hyenne, V.; Mittelheisser, V.; Krater, M.; Balzani, D.; Guck, J.; Osmani, N.; Goetz, J. G.

10.1101/2024.03.28.587171 — cancer biology — Posted on 2024-03-30

141 Oncogenic Phase Transitions: How Mutant p53 Drives Amyloid Formation in p63 and p73 Liquid Droplets

Petronilho, E. C.; de Andrade, G. C. C.; de Sousa, G. d. S.; Almeida, F. P.; Mota, M. F.; Marques, M. A.; Vieira, T. C. R. G.; de Oliveira, G. A. P.; Silva, J. L.

10.1101/2024.03.28.583974 — cancer biology — Posted on 2024-03-30

142 The importance of visual and chemical cues in infection detection and avoidance in a freshwater fish

Cote, A.; Binning, S. A.

10.1101/2024.03.27.587060 — animal behavior and cognition — Posted on 2024-03-30

143 Live Cell Fluorescence Microscopy - From Sample Preparation to Numbers and Plots

Zahumensky, J.; Malinsky, J.

10.1101/2024.03.28.587214 — cell biology — Posted on 2024-03-30

144 Structural factors of RGS14 regulating hormone-dependent phosphate transport mediated by NPT2A

Sneddon, W. B.; Ramineni, S.; Van Doorn, G. E.; Hepler, J. R.; Friedman, P.

10.1101/2024.03.29.586499 — cell biology — Posted on 2024-03-30

145 Use of Protein interactions from Imaging Complexes after Translocation (PICT) to characterise in situ the spatial configuration of proteins interacting with the exocyst

Chinchilla Hernandez, A.; Betancur Ocampo, L. I.; Picco, A.; Gallego, O.

10.1101/2024.03.28.587178 — cell biology — Posted on 2024-03-30

146 APP and β-amyloid modulate protein aggregation and dissociation from recycling endosomal and exosomal membranes

Singh, P. J.; Verma, B.; Wells, A.; Mendes, C. C.; Dunn, D.; Chen, Y.-N.; Oh, J.; Blincowe, L.; Wainwright, M.; Fischer, R.; Fan, S.-J.; Harris, A. L.; Goberdhan, D. C.; Wilson, C.

10.1101/2024.03.28.586966 — cell biology — Posted on 2024-03-30

147 Cyclocarya paliurus polysaccharides improve high fat diet-fed mice lipid dysmetabolism through gut microbiota

huang, c.; Jia, Y.; Chai, P.; He, H.; Liu, W.; Cheng, L.

10.1101/2024.03.30.587420 — microbiology — Posted on 2024-03-30

148 A multi-track landscape of haematopoiesis informed by cellular barcoding and agent-based modelling

Lin, D.; Zhang, S.; Schreuder, J.; Tran, J.; Metcalf, D.; Sargeant, T.; Ng, A. P.; Weber, T. S.; Naik, S.

10.1101/2024.03.28.587126 — immunology — Posted on 2024-03-30

149 Optogenetics-integrated gut organ culture system connects enteric neurons dynamics and gut homeostasis

Naim, G.; Romano, H.; Amidror, S.; Jessula Levy, D.; Cohen, A.; Sochen, C.; Yarden, Y.; Feng, M.; Farah, N.; Tsentsarevsky, R.; Brodie, Z.; Reich, Y.; Simon, A.; Toister, E.; Shoval, I.; Mandel, Y.; Biton, M.; Yissachar, N.

10.1101/2024.03.28.587149 — neuroscience — Posted on 2024-03-30

150 Resting-state fMRI reveals altered functional connectivity associated with resilience and susceptibility to chronic social defeat stress in mouse brain

Parent, C.; Lupinsky, D.; Nasseef, T.; Craig, K.; Diorio, J.; Zhang, T. Y.; Meaney, M. J.

10.1101/2024.03.28.587210 — neuroscience — Posted on 2024-03-30

151 A RALF-Brassinosteroid morpho-signaling circuit regulates Arabidopsis hypocotyl cell shape

Biermann, D.; von Arx, M.; Xhelilaj, K.; Sere, D.; Stegmann, M.; Wolf, S.; Zipfel, C.; Gronnier, J.

10.1101/2024.03.28.587199 — plant biology — Posted on 2024-03-30

152 Beyond enumeration: Phenotype independent "labeling-capture-release" process enabling precise detection of circulating tumour cells and downstream applications

Lao, Z.; Ren, X.; Zhuang, D.; Xie, L.; Zhang, Y.; Li, W.; Jiang, Z.; Chen, Y.; Li, P.; Tong, L.; Chu, P. K.; Wang, H.

10.1101/2024.03.27.586941 — bioengineering — Posted on 2024-03-30

153 EDSpliCE, a CRISPR-Cas9 gene editing platform to rescue splicing, effectively corrects inherited retinal dystrophy-associated splicing defects

De Angeli, P.; Shliaga, S.; Flores-Tufino, A.; Roschi, E.; Spaag, S.; Stingl, K.; Kuehlewein, L.; Wissinger, B.; Kohl, S.

10.1101/2024.03.27.587013 — genomics — Posted on 2024-03-30

154 Tissue-Specific Dynamics of TCF4 Triplet Repeat Instability Revealed by Optical Genome Mapping

Zarouchlioti, C.; Efthymiou, S.; Fracchini, S.; Dominik, N.; Bhattacharyya, N.; Liu, S.; Abreu Costa, M.; Szabo, A.; Sadan, A. N.; Jun, A.; Bugiardini, E.; Houlden, H.; Cortese, A.; Skalicka, P.; Dudakova, L.; Muthusamy, K.; Cheetham, M. E.; Hardcastle, A. J.; Liskova, P.; Tuft, S. J.; Davidson, A.

10.1101/2024.03.27.587034 — genomics — Posted on 2024-03-30

155 On the contribution of genetic heterogeneity to complex traits

Liu, H.-J.; Swarts, K.; Xu, S.; Yan, J.; Nordborg, M.

10.1101/2024.03.27.586967 — genetics — Posted on 2024-03-30

156 Enhanced metabolic entanglement emerges during the evolution of an interkingdom microbial community

Scarinci, G.; Ariens, J.-L.; Angelidou, G.; Schmidt, S.; Glatter, T.; Paczia, N.; Sourjik, V.

10.1101/2024.03.30.587424 — evolutionary biology — Posted on 2024-03-30

157 Energy-ordered resource stratification as an agnostic signature of life

Goyal, A.; Tikhonov, M.

10.1101/2024.03.27.586986 — ecology — Posted on 2024-03-30

158 Utilising citizen science data to rapidly assess potential wild bridging hosts and reservoirs of infection: avian influenza outbreaks in Great Britain

Vickers, S. H.; Raghwani, J.; Banyard, A. C.; Brown, I. H.; Fournie, G.; Hill, S. C.

10.1101/2024.03.28.587127 — ecology — Posted on 2024-03-30

159 A Gridded Microclimate Dataset from a Sub-Arctic Biodiversity Hotspot in Finland

Niittynen, P.; Salminen, H.; Pena-Aguilera, P.; Aalto, J.; Alahuhta, J.; Luoto, M.; Maliniemi, T.; Rissanen, T.; Roslin, T.; Tukiainen, H.; Tyystjarvi, V.; Kemppinen, J.

10.1101/2024.03.30.587419 — ecology — Posted on 2024-03-30

160 Arginine methylation of the p30 C/EBPα oncoprotein regulates progenitor proliferation and myeloid differentiation

Nguyen, L. T.; Zimmermann, K.; Kowenz-Leutz, E.; Dörr, D.; Schütz, A.; Schönheit, J.; Mildner, A.; Leutz, A.

10.1101/2024.03.28.587207 — cell biology — Posted on 2024-03-30

161 Physics and physiology determine strategies of bacterial investment in flagellar motility

Lisevich, I.; Colin, R.; Yang, H. Y.; Ni, B.; Sourjik, V.

10.1101/2024.03.30.587422 — microbiology — Posted on 2024-03-30

162 Nonuniform scaling of synaptic inhibition in the dorsolateral geniculate nucleus in a mouse model of glaucoma.

Van Hook, M. J.; McCool, S.

10.1101/2024.03.27.587036 — neuroscience — Posted on 2024-03-30

163 Tonic dendritic GABA release by substantia nigra dopaminergic neurons

Simmons, D. V.; Ding, J.; Khakh, B.; Awatramani, R. V.; Surmeier, D. J.

10.1101/2024.03.27.586699 — neuroscience — Posted on 2024-03-30

164 Circadian control of a sex-specific behaviour in Drosophila

Franco, D. L.; Riva, S.; Ceriani, M. F.; Risau-Gusman, S.

10.1101/2024.03.27.586991 — neuroscience — Posted on 2024-03-30

165 Neurophysiology of effortful listening: Decoupling motivational modulation from task demands

Kraus, F.; Ross, B.; Herrmann, B.; Obleser, J.

10.1101/2024.03.27.587038 — neuroscience — Posted on 2024-03-30

166 Hippocampal Signal Complexity and Rate-of-Change Predict Navigational Performance: Evidence from a Two-Week VR Training Program

Ozubko, J.; Campbell, M.; Verhayden, A.; Demetri, B.; Brady, M.; Sivashankar, Y.; Brunec, I. K.

10.1101/2024.03.27.587026 — neuroscience — Posted on 2024-03-30

167 The fMRI global signal and its association with the signal from cranial bone

Huber, D. A.; Rabl, L.; Orsini, C.; Labek, K.; Viviani, R.

10.1101/2024.03.27.587003 — neuroscience — Posted on 2024-03-30

168 Low-Dimensional Representations of Visuomotor Coordination for Natural Behavior

Keshava, A.; Waechter, M. A.; Bosse, F.; Schueler, T.; Koenig, P.

10.1101/2024.03.30.587357 — neuroscience — Posted on 2024-03-30

169 Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling

Le Gac, B.; Tournissac, M.; Belzic, E.; Picaud, S.; Dusart, I.; Soula, H.; Li, D.; Charpak, S.; Cauli, B.

10.1101/2024.03.27.586974 — neuroscience — Posted on 2024-03-30

170 Large-scale RNA-seq mining reveals ciclopirox triggers TDP-43 cryptic exons

Sinha, I. R.; Sandal, P. S.; Burns, G. D.; Mallika, A. P.; Irwin, K. E.; Cruz, A. L. F.; Wang, V.; Rodriguez, J. L.; Wong, P. C.; Ling, J. P.

10.1101/2024.03.27.587011 — neuroscience — Posted on 2024-03-30

171 Oscillatory dynamics of Rac1 activity in Dictyostelium discoideum amoebae

Sostar, M.; Marinovic, M.; Filic, V.; Pavin, N.; Weber, I.

10.1101/2024.03.28.587124 — systems biology — Posted on 2024-03-30

172 Synchronization of Circadian Clock Gene Expression in Arabidopsis and Hyaloperonospora arabidopsidis and its Impact on Host-Pathogen Interactions

Telli, O.; Gol, D.; Jin, W.; Cevher-Keskin, B.; Hong, Y.; McDowell, J.; Studholme, D. J.; Tor, M.

10.1101/2024.03.27.586998 — plant biology — Posted on 2024-03-30

173 HPV-positive head and neck squamous cell carcinoma cells lose viability during triggered myocyte lineage differentiation

Gendreizig, S.; Martinez-Ruiz, L.; Lopez-Rodriguez, A.; Pabla, H.; Hose, L.; Brasch, F.; Busche, T.; Escames, G.; Sudhoff, H.; Scholtz, L. U.; Todt, I.; Oppel, F.

10.1101/2024.03.28.587125 — cancer biology — Posted on 2024-03-30

174 Multi-Omics Analysis Reveals the Attenuation of the Interferon Pathway as a Driver of Chemo-Refractory Ovarian Cancer

Afenteva, D.; Yu, R.; Rajavuori, A.; Salvadores, M.; Launonen, I.-M.; Lavikka, K.; Zhang, K.; Marchi, G.; Jamalzadeh, S.; Isoviita, V.-M.; Li, Y.; Micoli, G.; Erkan, E. P.; Falco, M. M.; Ungureanu, D.; Lahtinen, A.; Oikkonen, J.; Hietanen, S.; Vaharautio, A.; Sur, I.; Virtanen, A.; Farkkila, A.; Hynninen, J.; Muranen, T. A.; Taipale, J.; Hautaniemi, S.

10.1101/2024.03.28.587131 — cancer biology — Posted on 2024-03-30

175 Learning and actioning general principles of cancer cell drug sensitivity

Raimondi, F.; Di Chiaro, P.; Morelli, M.; Arora, C.; Bisceglia, L.; De Oliveira Rosa, N.; Cortesi, A.; Franceschi, S.; Lessi, F.; Di Stefano, A. L.; Santonocito, O. S.; Pasqualetti, F.; Aretini, P.; Miglionico, P.; Diaferia, G. R.; Giannotti, F.; Lio, P.; Duran-Frigola, M.; Mazzanti, C. M.; Natoli, G.; Raimondi, F.

10.1101/2024.03.28.586783 — bioinformatics — Posted on 2024-03-30

176 MegaKG: Toward an explainable knowledge graph for early drug development

Dong, J.; Liu, J.; Wei, Y.; Huang, P.; Wu, Q.

10.1101/2024.03.27.586981 — bioinformatics — Posted on 2024-03-30

177 LeGenD: determining N-glycoprofiles using an explainable AI-leveraged model with lectin profiling

Li, H.; Peralta, A. G.; Schoffelen, S.; Hansen, A. H.; Arnsdorf, J.; Schinn, S.-M.; Skidmore, J.; Choudhury, B.; Paulchakrabarti, M.; Voldborg, B. G.; Chiang, A. W. T.; Lewis, N. E.

10.1101/2024.03.27.587044 — bioengineering — Posted on 2024-03-30

178 A novel functional gene delivery platform based on a commensal human anellovirus demonstrates transduction in multiple tissue types

Prince, C.; Bounoutas, G.; Zhou, B.; Raja, W.; Gold, I.; Pozsgai, R.; Thakker, P.; Boisvert, N.; Reardon, C.; Thurmond, S.; Ozturk, E.; Boggavarapu, R.; Springer, S.; Chahal, L.; Nogalski, M.; Ong, T.; Nawandar, D.; Wright, C.; Mackey, A.; Parsons, G.; Cabral, J.

10.1101/2024.03.27.586964 — bioengineering — Posted on 2024-03-30

179 Assessment of Plant- and Microbial-Derived Protein Hydrolysates as Sustainable for Fetal Bovine Serum in Seafood Cell Culture Media

Amirvaresi, A.; Ovissipour, R.

10.1101/2024.03.27.587063 — bioengineering — Posted on 2024-03-30

180 Towards prospective in-silico trials in atrial fibrillation: the case of polypharmacological SK and K2P channel block

Dasi, A.; Berg, L. A.; Martinez-Navarro, H.; Bueno-Orovio, A.; Rodriguez, B.

10.1101/2024.03.30.586087 — bioengineering — Posted on 2024-03-30

181 Research disturbance negatively impacts incubation behaviour of female Great Tits

Clemencin, L.; Barba, E.; Diez-Mendez, D.

10.1101/2024.03.28.587136 — animal behavior and cognition — Posted on 2024-03-30

182 Evolutionary divergence between homologous X-Y chromosome genes shapes sex-biased biology

DeCasien, A. R.; Tsai, K.; Liu, S.; Thomas, A.; Raznahan, A.

10.1101/2024.03.27.586985 — genomics — Posted on 2024-03-30

183 Genomic and transcriptomic analyses of the elite rice variety Huizhan provide insight into disease resistance and heat tolerance

Wei, Y.; Yang, Z.; Yang, L.; Li, Z.; Zhang, Z.; Wei, T.; Huang, R.; Li, G.

10.1101/2024.03.30.587414 — genomics — Posted on 2024-03-30

184 Transposable elements as evolutionary driving force to ecological speciation in cactophilic Drosophila species

Oliveira, D. S. d.; Larue, A.; Nunes, W. V. B.; Sabot, F.; Bodelon, A.; Guerreiro, M. P. G.; Vieira, C.; Carareto, C. M.

10.1101/2024.03.27.587021 — evolutionary biology — Posted on 2024-03-30

185 Short lifespan is one's fate, long lifespan is one's achievement: lessons from Daphnia

Beam, T. C.; Bright, M. P.; Pearson, A. C.; Dua, I.; Dutta, A. K.; Smith, M. L.; Bhadra, S.; Strickler, C. N.; Salman, S.; Anderson, C. E.; Peshkin, L.; Yampolsky, L. Y.

10.1101/2024.03.30.587428 — ecology — Posted on 2024-03-30

186 Life-history adaptation under climate warming magnifies the agricultural footprint of a cosmopolitan insect pest

Burc, E.; Girard-Tercieux, C. E.; Metz, M.; Cazaux, E.; Baur, J.; Koppik, M.; Rego, A.; Hart, A.; Berger, D.

10.1101/2024.03.30.587412 — ecology — Posted on 2024-03-30

187 Vitamin C prevents S. aureus infections of endothelial cells through its interaction with specific residues in the active site of gC1qR/p33 involved in direct entry, notably SER230, ASN345, ILE348, TYR224, ASN346, SER347, and GLU438, and its potential inhibitory effects on FnBPs, α5β1, and Protein A molecules

Miliani, M.; Hadjidj, Z.; Bensefia, Z.; Dahou, S.; Ammouche, N.; Hamdoun, I.; Benammar, H.; Benammar, S.; Aribi, M.

10.1101/2024.03.27.586894 — immunology — Posted on 2024-03-30

188 Uncertainty in Thermosensory Expectations Enhances an Illusion of Pain

Ehmsen, J. F.; Nikolova, N.; Christensen, D. E.; Banellis, L.; Braendholt, M.; Courtin, A. S.; Kraenge, C. E.; Mitchell, A. G.; Deolindo, C. S.; Steenkjaer, C.; Vejloe, M.; Mathys, C.; Allen, M. G.; Fardo, F.

10.1101/2024.03.27.587070 — neuroscience — Posted on 2024-03-30

189 Epigenomic landscape of the human dorsal root ganglion: sex differences and transcriptional regulation of nociceptive genes

Franco-Enzastiga, U.; Inturi, N. N.; Natarajan, K.; Mwirigi, J. M.; Mazhar, K.; Schlachetzki, J. C.; Schumacher, M.; Price, T. J.

10.1101/2024.03.27.587047 — neuroscience — Posted on 2024-03-30

190 Force Reserve Predicts Compensation in Reaching Movement with Induced Shoulder Strength Deficit

Faity, G.; Barradas, V. R.; Schweighofer, N.; Mottet, D.

10.1101/2024.03.28.587142 — neuroscience — Posted on 2024-03-30

191 The laminar organization of cell types in macaque cortex and its relationship to neuronal oscillations

Lichtenfeld, M. J.; Mulvey, A. G.; Nejat, H.; Xiong, Y. S.; Carlson, B. M.; Mitchell, B. A.; Mendoza-Halliday, D.; Westerberg, J. A.; Desimone, R.; Maier, A.; Kaas, J. H.; Bastos, A. M.

10.1101/2024.03.27.587084 — neuroscience — Posted on 2024-03-30

192 Human visual performance for identifying letters affected by physiologically-inspired scrambling

Zhu, X. R.; Hess, R. F.; Baldwin, A. S.

10.1101/2024.03.27.583720 — neuroscience — Posted on 2024-03-30

193 The Neural Basis of Attentional Blink as a Selective Control Mechanism in Conscious Perception

Xin, Q.; Forman, S.; Christison-Lagay, K.; Micek, C.; Kronemer, S.; Aksen, M.; Grobois, L.; Contreras Ramirez, V.; Khalaf, A.; Jin, D.; Aerts, S.; Chun, M.; Crowley, M.; Blumenfeld, H.

10.1101/2024.03.30.587354 — neuroscience — Posted on 2024-03-30

194 α-Synuclein strain propagation is independent of cellular prion protein expression in transgenic mice

So, R. W. L.; Stuart, E.; Amini, A. E.; Aguzzi, A.; Collingridge, G. L.; Watts, J. C.

10.1101/2024.03.27.587028 — neuroscience — Posted on 2024-03-30

195 Synaptic function and sensory processing in ZDHHC9-associated neurodevelopmental disorder: a mechanistic account

Ianov-Vitanov, R.; Achterberg, J.; Akarca, D.; Astle, D.; Baker, K.

10.1101/2024.03.28.587155 — neuroscience — Posted on 2024-03-30

196 Transcriptomic analysis of the juvenile to adult transition in the mouse corpus callosum

Hoshino, T.; Takase, H.; Hamanaka, G.; Kimura, S.; Fukuda, N.; Mandeville, E. T.; Lok, J.; Lo, E. H.; Arai, K.

10.1101/2024.03.28.587148 — neuroscience — Posted on 2024-03-30

197 Lineage-tracing reveals an expanded population of NPY neurons in the inferior colliculus

Silveira, M. A.; Herrera, Y. N.; Beebe, N. L.; Schofield, B. R.; Roberts, M. T.

10.1101/2024.03.27.587042 — neuroscience — Posted on 2024-03-30

198 Network medicine informed multi-omics integration identifies drug targets and repurposable medicines for Amyotrophic Lateral Sclerosis

Yu, M.; Dutta, R.; Trapp, B.; Pieper, A. A.; Cheng, F.

10.1101/2024.03.27.586949 — systems biology — Posted on 2024-03-30

199 The CRISPRaTOR: a biomolecular circuit for Automatic Gene Regulation in Mammalian Cells with CRISPR technology.

Mallozzi, A.; Fusco, V.; Ragazzini, F.; di Bernardo, D.

10.1101/2024.03.30.587417 — synthetic biology — Posted on 2024-03-30

200 Characterisation of cuticle mechanical properties: analysing stiffness in layered living systems to understand surface buckling patterns

Airoldi, C. A.; Chen, C.; Herrera-Ubaldo, H.; Fu, H.; Lugo, C. A.; Crosby, A. J.; Glover, B. J.

10.1101/2024.03.27.587033 — plant biology — Posted on 2024-03-30

201 Wounding perception by jasmonate-mediated JAZ condensation in plants

Yan, Z.-W.; Liu, J.; Chen, H.-C.; Wang, M.-Y.; Cai, W.-J.; Li, J.-X.; Wang, J.-W.; Mao, Y.-B.

10.1101/2024.03.28.587122 — plant biology — Posted on 2024-03-30

202 Modeling cardiorespiratory coherence in exercise anticipation

koppula, A.; Sridharan, K. S.; Raghavan, M.

10.1101/2024.03.27.587091 — physiology — Posted on 2024-03-30

203 Activation of IP3R in atrial cardiomyocytes leads to generation of cytosolic cAMP

Akerman, E. C.; Read, M. J.; Bose, S. J.; Koschinski, A.; Capel, R. A.; Chao, Y.-C.; Folkmanaite, M.; Hester, S.; Fischer, R.; Ayagama, T.; Broadbent, S. D.; Ahamed, R.; Simon, J. N.; Terrar, D. A.; Zaccolo, M.; Burton, R.-A. B.

10.1101/2024.03.28.583721 — physiology — Posted on 2024-03-30

204 Cryo-electron tomography reveals the nanoscale architecture of the actin cortex in cellular blebs

Cassani, D. A. D.; Martins, B.; Smith, M. B.; Medalia, O.; Paluch, E. K.

10.1101/2024.03.30.587413 — biophysics — Posted on 2024-03-30

205 Elucidating the link between binding statistics and Shannon information in biological cooperative networks

BANERJEE, K.; DAS, B.

10.1101/2024.03.28.587158 — biophysics — Posted on 2024-03-30

206 Deciphering the Timing and Impact of Life-extending Drugs: A Novel Analytic Approach that Differentiates Early, Midlife, and Senescence Phase Efficacies.

Jiang, N.; Cheng, C. J.; Liu, Q.; Strong, R.; Gelfond, J.; Nelson, J. F.

10.1101/2024.03.27.585737 — bioinformatics — Posted on 2024-03-30

207 multimedia: Multimodal Mediation Analysis of Microbiome Data

Jiang, H.; Miao, X.; Thairu, M. W.; Beebe, M.; Grupe, D. W.; Davidson, R. J.; Handelsman, J.; Sankaran, K.

10.1101/2024.03.27.587024 — bioinformatics — Posted on 2024-03-30

208 A starting guide on multi-omic single-cell data joint analysis: basic practices and results

Martini, L.; Bardini, R.; Di Carlo, S.

10.1101/2024.03.30.587427 — bioinformatics — Posted on 2024-03-30

209 ORCA: Predicting replication origins in circular prokaryotic chromosomes

van Meel, Z.; Baaijens, J. A.

10.1101/2024.03.28.587133 — bioinformatics — Posted on 2024-03-30

210 MolSnapper: Conditioning Diffusion for Structure Based Drug Design

Ziv, Y.; Marsden, B.; Deane, C.

10.1101/2024.03.28.586278 — bioinformatics — Posted on 2024-03-30

211 Design and Assembly of a Cargo-agnostic Hollow Two-lidded DNA Box for Drug Delivery

Koep, A.; Masud, N.; Van't Hul, J.; Stanley, C.; Nilsen-Hamilton, M.; Sarkar, A.; Schneider, I. C.

10.1101/2024.03.27.586853 — bioengineering — Posted on 2024-03-30

212 inSequio: A Programmable 3D CAD Application for Designing DNA Nanostructures

LaRock, C.; Sorensen, P.; Blair, D.; Murphy, D.; O'Connor, J.; Armentrout, S.

10.1101/2024.03.27.586810 — bioengineering — Posted on 2024-03-30

213 Glycoengineered recombinant alpha1-antitrypsin results in comparable in vitro and in vivo activities to human plasma-derived protein

Rocamora, F.; Schoffelen, S.; Arnsdorf, J.; Toth, E. A.; Abdul, Y.; Cleveland, T. E.; Bjorn, S. P.; Wu, M. Y. M.; McElvaney, N. G.; Voldborg, B. G. R.; Fuerst, T. R.; Lewis, N. E.

10.1101/2024.03.27.587088 — bioengineering — Posted on 2024-03-30

214 Tracking of Lineage Mass via Quantitative Phase Imaging and Confinement in Low Refractive Index Microwells

Zhang, J.; Griffin, J.; Roy, K.; Hoffmann, A.; Zangle, T. A.

10.1101/2024.03.27.587085 — bioengineering — Posted on 2024-03-30

215 Global DNA Hypomethylation as a Biomarker of Accelerated Epigenetic Ageing in Primates

Girling, M. T. S.; Sanchez Perea, N.; Paredes, U.

10.1101/2024.03.27.586982 — animal behavior and cognition — Posted on 2024-03-30

216 CARPDM: cost-effective antibiotic resistome profiling of metagenomic samples using targeted enrichment

Hackenberger, D.; Imtiaz, H.; Raphenya, A. R.; Alcock, B. P.; Poinar, H. N.; Wright, G. D.; McArthur, A. G.

10.1101/2024.03.27.587061 — genomics — Posted on 2024-03-30

217 The haplotype-resolved Prymnesium parvum (type B) microalga genome reveals the genetic basis of its fish-killing toxins

Kuhl, H.; Strassert, J. F. H.; Certnerova, D.; Varga, E.; Kreuz, E.; Lamatsch, D. K.; Wuertz, S.; Köhler, J.; Monaghan, M. T.; Stöck, M.

10.1101/2024.03.27.587007 — genomics — Posted on 2024-03-30

218 A shared genetic basis for sexually antagonistic male and female adaptations in the toothed water strider

Pruvot, C.; Armisen, D.; Roux, P.; Arnqvist, G.; Rowe, L.; Husby, A.; Khila, A.

10.1101/2024.03.27.586914 — evolutionary biology — Posted on 2024-03-30

219 Pitfalls and windfalls of detecting demographic declines using population genetics in long-lived species

Clark, M. I.; Fitzpatrick, S. W.; Bradburd, G. S.

10.1101/2024.03.27.586886 — evolutionary biology — Posted on 2024-03-30

220 GENETIC DIVERSITY AFFECTS ECOSYSTEM FUNCTIONS ACROSS TROPHIC LEVELS AS MUCH AS SPECIES DIVERSITY, BUT IN AN OPPOSITE DIRECTION

Fargeot, L.; Poesy, C.; Lefort, M.; Prunier, J. G.; Krick, M.; Verdonck, R.; Veyssiere, C.; Richard, M.; Legrand, D.; Loot, G.; Blanchet, S.

10.1101/2024.03.27.586944 — ecology — Posted on 2024-03-30

221 On the recovery of malformed horseshoe crabs across multiple moulting stages

Bicknell, R. D. C.; Cuomo, C.

10.1101/2024.03.27.587089 — ecology — Posted on 2024-03-30

222 Effect of urbanization on the city pollution based on soil and tree leaves in Valencia, Spain

Edina, S.; Bin, I. H.; Sipos, B.; Abriha-Molnar, V. E.; Abriha, D.; Boluda, H. R.; Perez, L. R.

10.1101/2024.03.27.586674 — ecology — Posted on 2024-03-30

223 Evolution of predators and prey kills Turing patterns

Piskovsky, V.

10.1101/2024.03.28.587143 — ecology — Posted on 2024-03-30

224 Human chorionic gonadotropin decreases cerebral cystic encephalomalacia and parvalbumin interneuron degeneration in a pro-inflammatory model of mouse neonatal hypoxia-ischemia.

Galindo, R.; Aravamuthan, B. R.; Miller, B.; Crider, A.

10.1101/2024.03.27.587006 — neuroscience — Posted on 2024-03-30

225 Multiple and subject-specific roles of uncertainty in reward-guided decision-making

Paunov, A.; L'Hotellier, M.; He, Z.; Guo, D.; Yu, A.; Meyniel, F.

10.1101/2024.03.27.587016 — neuroscience — Posted on 2024-03-30

226 Violated predictions enhance the representational fidelity of visual features in perception

Rideaux, R.; Dang, P.; Jackel-David, L.; Buhmann, Z.; Rangelov, D.; Mattingley, J. B.

10.1101/2024.03.27.587109 — neuroscience — Posted on 2024-03-30

227 Lipid Specificity of the Fusion of Bacterial Extracellular Vesicles with the Host Membrane

Prince, A.; Tiwari, A.; Mandal, T.; Koiri, D.; Meher, G.; Sinha, D. K.; Saleem, M.

10.1101/827519 — biophysics — Posted on 2024-03-30

228 A high-throughput method for quantifying Drosophila fecundity

Gomez, A.; Gonzalez, S.; Oke, A.; Luo, J.; Duong, J. B.; Esquerra, R. M.; Zimmerman, T.; Capponi, S.; Fung, J. C.; Nystul, T. G.

10.1101/2024.03.27.587093 — genetics — Posted on 2024-03-30

229 Development of Pial Collaterals by Extension of Pre-existing Artery Tips

Kumar, S.; Shanavas, N.; Ghosh, S.; Sivaramakrishnan, V.; Dwari, M.; Das, S.

10.1101/2023.12.07.570539 — developmental biology — Posted on 2024-03-30

230 MX2 restricts HIV-1 and herpes simplex virus type 1 by forming cytoplasmic biomolecular condensates that mimic nuclear pore complexes

Moschonas, G. D.; Delhaye, L.; Cooreman, R.; Husers, F.; Bath, A.; De Sutter, D.; Parthoens, E.; Desmet, A.-S.; Maciejczuk, A.; Grzesik, H.; Lippens, S.; Debyser, Z.; Sodeik, B.; Eyckerman, S.; Saelens, X.

10.1101/2023.06.22.545931 — microbiology — Posted on 2024-03-30

231 Dopamine neurons drive spatiotemporally heterogeneous striatal dopamine signals during learning

Engel, L.; Wolff, A. R.; Blake, M.; Collins, V. L.; Sinha, S.; Saunders, B. T.

10.1101/2023.07.01.547331 — neuroscience — Posted on 2024-03-30

232 Trehalose-based coacervates for local bioactive protein delivery to the central nervous system

Hassan, L. F.; Sen, R.; O'Shea, T. M.

10.1101/2023.10.05.561124 — bioengineering — Posted on 2024-03-30

233 Robust characterization of forest structure from airborne laser scanning - a systematic assessment and sample workflow for ecologists

Fischer, F. J.; Jackson, T. D.; Vincent, G.; Jucker, T.

10.1101/2024.03.27.586702 — ecology — Posted on 2024-03-30

234 Immediate glucose signaling transmitted via the vagus nerve in gut-brain neural communication

Yamada, S.; Natsubori, A.; Harada, K.; TSUBOI, T.; Monai, H.

10.1101/2024.03.27.586971 — neuroscience — Posted on 2024-03-30

235 Sensory processing sensitivity is associated with neural synchrony and functional connectivity during threatening movies

Damatac, C. G.; Homberg, J. R.; Galesloot, T. E.; Geerligs, L.; Greven, C. U.

10.1101/2024.03.27.586963 — neuroscience — Posted on 2024-03-30

236 Bayesian inference of phylogenetic distances: revisiting the eigenvalue approach

Penn, M. J.; Scheidwasser, N.; Donnelly, C. A.; Duchene, D. A.; Bhatt, S.

10.1101/2024.03.27.586929 — evolutionary biology — Posted on 2024-03-30

237 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants

Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.

10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-30

238 Learning enhances behaviorally relevant representations in apical dendrites

Benezra, S. E.; Patel, K. B.; Perez Campos, C.; Hillman, E. M. C.; Bruno, R. M.

10.1101/2021.11.10.468144 — neuroscience — Posted on 2024-03-30

239 Modulation of Human Frontal Midline Theta by Neurofeedback: A Systematic Review and Quantitative Meta-Analysis

Pfeiffer, M.; Kuebler, A.; Hilger, K.

10.1101/2023.11.10.566628 — neuroscience — Posted on 2024-03-30

240 Neural Correlates of Different Randomization Tasks

Guseva, M.; Bogler, C.; Allefeld, C.; Ziya, E. B.; Haynes, J.-D.

10.1101/2024.03.27.586961 — neuroscience — Posted on 2024-03-30

241 Dynamic Gamma Modulation of Hippocampal Place Cells Predominates Development of Theta Sequences

Wang, N.; Wang, Y.; Guo, M.; Wang, L.; Wang, X.; Zhu, N.; Yang, J.; Wang, L.; Zheng, C.; Ming, D.

10.1101/2024.03.27.586908 — neuroscience — Posted on 2024-03-30

242 Behavior and alpha-band oscillations reveal cross-modal interactions between chemosensory and auditory processing

Klatt, L.-I.; Hucke, C. I.

10.1101/2024.03.27.586970 — neuroscience — Posted on 2024-03-30

243 A Set of FMRI Quality Control Tools in AFNI: Systematic, in-depth and interactive QC with afni_proc.py and more

Taylor, P. A.; Glen, D.; Chen, G.; Cox, R. W.; Hanayik, T.; Rorden, C.; Nielson, D. M.; Rajendra, J. K.; Reynolds, R. C.

10.1101/2024.03.27.586976 — neuroscience — Posted on 2024-03-30

244 Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.

Hoffner, G.; Castro, P.; Uhrig, L.; Signorelli, C. M.; Dupont, M.; Tasserie, J.; Destexhe, A.; Cofre, R.; Sitt, J.; Jarraya, B.

10.1101/2024.03.27.586806 — neuroscience — Posted on 2024-03-30

245 NASTRA: Accurate analysis of short tandem repeat markers by nanopore sequencing with repeat-structure-aware algorithm

Ren, Z.; Zhang, J.; Zhang, Y.; Yang, T.; Sun, P.; Xue, J.; Bo, X.; Zhou, B.; Yan, J.; Ni, M.

10.1101/2023.11.04.565630 — bioinformatics — Posted on 2024-03-30

246 Graph Contrastive Learning of Subcellular-resolution Spatial Transcriptomics Improves Cell Type Annotation and Reveals Critical Molecular Pathways

Lu, Q.; Ding, J.; Li, L.; Chang, Y.; Tang, J.; Qiu, X.

10.1101/2024.03.08.584192 — bioinformatics — Posted on 2024-03-30

247 A new cellular platform for studying autophagy

Goldin-Azulay, K.; Fraiberg, M.; Trofimyuk, O.; Reuven, N.; Levin, Y.; Kopitman, E.; Elazar, Z.

10.1101/2024.03.28.587157 — cell biology — Posted on 2024-03-30

248 DIETARY REGULATION OF SILENT SYNAPSES IN THE DORSOLATERAL STRIATUM

Meyers, A. M.; Gnazzo, F.; Barrera, E. D.; Nabatian, T.; Chan, L.; Beeler, J.

10.1101/2024.03.24.586457 — neuroscience — Posted on 2024-03-30

249 SPLASH2 provides ultra-efficient, scalable, and unsupervised discovery on raw sequencing reads

Kokot, M.; Dehghannasiri, R.; Baharav, T. Z.; Salzman, J.; Deorowicz, S.

10.1101/2023.03.17.533189 — bioinformatics — Posted on 2024-03-30

250 LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

Busley, A. V.; Gutierrez-Gutierrez, O.; Hammer, E.; Koitka, F.; Mirzaiebadizi, A.; Steinegger, M.; Pape, C.; Boehmer, L.; Schroeder, H.; Kleinsorge, M.; Engler, M.; Cirstea, I. C.; Gremer, L.; Willbold, D.; Altmueller, J.; Marbach, F.; Hasenfuss, G.; Zimmermann, W.-H.; Ahmadian, M. R.; Wollnik, B.; Cyganek, L.

10.1101/2023.01.10.523203 — cell biology — Posted on 2024-03-29

251 Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons

Subedi, A.; Tiwari, A.; Etemad, A. F.; Huang, Y.; Chatterjee, B.; McLeod, S. L.; Lu, Y.; Gonzalez, D.; Ghosh, K.; Singh, S. K.; Ruiz Echartea, M. E.; Grimm, S. L.; Coarfa, C.; Pan, H.-L.; Majumder, S.

10.1101/2024.02.17.579842 — neuroscience — Posted on 2024-03-29

252 Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum

Cheng, Y.; Magnard, R.; Langdon, A. J.; Lee, D.; Janak, P. H.

10.1101/2024.03.10.584332 — neuroscience — Posted on 2024-03-29

253 An optimized somatic embryo transformation system assisted homozygous edited rubber tree generation method mediated by CRISPR/Cas9

Yang, X.; Lin, Q.; Udayabhanu, J.; Hua, Y.; Dai, X.; Xin, S.; Wang, X.; Huang, H.; Huang, T.

10.1101/2024.03.14.585007 — plant biology — Posted on 2024-03-29

254 OpenNucleome for high resolution nuclear structural and dynamical modeling

Lao, Z.; Kamat, K. D.; Jiang, Z.; Zhang, B.

10.1101/2023.10.16.562451 — biophysics — Posted on 2024-03-29

255 Targeted drug release from stable and safe ultrasound-sensitive nanocarriers

Wilson, M. G.; Parikh, A.; Dara, A.; Beaver, A. S.; Kubanek, J.

10.1101/2021.12.14.471689 — bioengineering — Posted on 2024-03-29

256 Shear Stress Initiates Endothelial to Mesenchymal Transition in Endocardial Endothelial Cells

Brown, K. N.; Phan, H. K. T.; Mustafa, T.; Jui, E.; Ahmad, F. N.; Birla, R. K.; Connell, J. P.; Sucosky, P.; Keswani, S. G.; Grande-Allen, K. J.

10.1101/2022.12.05.519049 — bioengineering — Posted on 2024-03-29

257 Nonadjacent Dependencies and Syntactic Structure of Chimpanzee Action During a Natural Tool-Use Task

Howard-Spink, E.; Hayashi, M.; Matsuzawa, T.; Schofield, D.; Gruber, T.; Biro, D.

10.1101/2024.03.25.586385 — animal behavior and cognition — Posted on 2024-03-29

258 Evolution of Opsin Genes in Caddisflies (Insecta: Trichoptera)

Powell, A.; Heckenhauer, J.; Pauls, S. U.; Rios-Touma, B.; Kuranishi, R. B.; Holzenthal, R. W.; Razuri-Gonzales, E.; Bybee, S.; Frandsen, P. B.

10.1101/2023.12.15.571940 — genomics — Posted on 2024-03-29

259 Aging-associated long non-coding RNA boosts longevity and reduces the ribosome content of non-dividing fission yeast cells

Anver, S.; Sumit, A. F.; Sun, X.-M.; Hatimy, A.; Thalassinos, K.; Marguerat, S.; Alic, N.; Bahler, J.

10.1101/2024.03.25.586524 — genetics — Posted on 2024-03-29

260 Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior

Keys, J. T.; Cheung, B. C. H.; Elpers, M. A.; Wu, M.; Lammerding, J.

10.1101/2022.09.10.507419 — cell biology — Posted on 2024-03-29

261 Ablation of Mitochondrial RCC1-L Induces Nigral Dopaminergic Neurodegeneration and Parkinsonian-like Motor Symptoms

Ellioff, K.; Osting, S. M.; Lentine, A.; Welper, A. D.; Burger, C.; Greenspan, D. S.

10.1101/2023.12.01.567409 — neuroscience — Posted on 2024-03-29

262 Defining the function of disease variants with CRISPR editing and multimodal single cell sequencing

Baglaenko, Y.; Curtis, M.; Al Suqri, M.; Agnew, R.; Mire, H. M.; Mah-Som, A. Y.; Liu, D. R.; Newby, G. A.; Raychaudhuri, S.

10.1101/2024.03.28.587175 — genomics — Posted on 2024-03-29

263 Molecular insights into G protein specificity and biased agonism at the β2-adrenergic receptor

Casiraghi, M.; Wang, H.; Brennan, P.; Habrian, C.; Hubner, H.; Schmidt, M. F.; Maul, L.; Pani, B.; Bahriz, S. M.; Xu, B.; White, E.; Sunahara, R. K.; Xiang, Y. K.; Lefkowitz, R. J.; Isacoff, E. Y.; Nucci, N.; Gmeiner, P.; Lerch, M.; Kobilka, B. K.

10.1101/2024.03.28.587240 — molecular biology — Posted on 2024-03-29

264 From resonance to chaos: modulating spatiotemporal patterns through a synthetic optogenetic oscillator

Park, J. H.; Hollo, G.; Schaerli, Y.

10.1101/2024.03.28.586779 — synthetic biology — Posted on 2024-03-29

265 Structural basis of eukaryotic transcription termination by the Rat1 exonuclease complex

Yanagisawa, T.; Murayama, Y.; Ehara, H.; Goto, M.; Aoki, M.; Sekine, S.-i.

10.1101/2024.03.28.587100 — biochemistry — Posted on 2024-03-29

266 Remodeling Ca2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer.

Chatterjee, O.; Jana, J.; Panda, S.; Dutta, A.; Sharma, A.; Saurav, S.; Motiani, R. K.; Weisz, K.; Chatterjee, S.

10.1101/2024.03.28.587164 — biochemistry — Posted on 2024-03-29

267 Uncovering nick DNA binding by LIG1 at the single-molecule level

Chatterjee, S.; Chaubet, L.; Berg, A. v. d.; Mukhortava, A.; Caglayan, M.

10.1101/2024.03.28.587287 — biochemistry — Posted on 2024-03-29

268 Assessing Target of Rapamycin (TOR) activity in the diatom Phaeodactylum tricornutum using commercially available materials

Tsuji, Y.; Ishikawa, T.

10.1101/2024.03.28.587301 — biochemistry — Posted on 2024-03-29

269 Elucidating microRNA-34a organisation within Human Argonaute-2 by NMR

Dasgupta, R.; Becker, W.; Petzold, K.

10.1101/2024.03.28.587161 — biochemistry — Posted on 2024-03-29

270 Wrapping of single-stranded DNA by Replication Protein A and modulation through phosphorylation

Chadda, R.; Kaushik, V.; Ahmad, I. M.; Deveryshetty, J.; Holehouse, A. S.; Sigurdsson, S. T. d.; Bothner, B.; Dastvan, R.; Origanti, S. S.; Antony, E.

10.1101/2024.03.28.587234 — biochemistry — Posted on 2024-03-29

271 An artificial intelligence accelerated virtual screening platform for drug discovery

Zhou, G.; Rusnac, D.-V.; Park, H.; Canzani, D.; Nguyen, H. M.; Stewart, L.; Bush, M. F.; Nguyen, P. T.; Wulff, H.; Yarov-Yarovoy, V.; Zheng, N.; DiMaio, F.

10.1101/2024.03.28.587262 — biochemistry — Posted on 2024-03-29

272 Abolished frameshifting for predicted structure-stabilizing SARS-CoV-2 mutants: Implications to alternative conformations and their statistical structural analyses

Dey, A.; Laederach, A.; Yan, S.; Schlick, T.

10.1101/2024.03.28.586935 — molecular biology — Posted on 2024-03-29

273 A palette of bright and photostable monomeric fluorescent proteins for bacterial time-lapse imaging

Fraikin, N.; Couturier, A.; Lesterlin, C.

10.1101/2024.03.28.587235 — molecular biology — Posted on 2024-03-29

274 The structure and diversity of the bacterial community in the overlying water of the Yangzong Lake in Yunnan

Huang, K.; Li, L.; Li, J.; Chen, H.; Ma, Z.; Ye, W.; Kong, D.; Zhang, J.

10.1101/2024.03.28.587311 — microbiology — Posted on 2024-03-29

275 Striated fibre assemblins localise in the feeding groove of the 'typical excavate' Paratrimastix pyriformis

Heiss, A. A.; Fang, Y.-K.; Pena-Diaz, P.; Zitek, J.; Novak, J.; Smida, A.; Zelena, M.; Svagr, E.; Hampl, V.

10.1101/2024.03.29.587336 — microbiology — Posted on 2024-03-29

276 MiFoDB, a workflow for microbial food metagenomic characterization, enables high-resolution analysis of fermented food microbial dynamics

Caffrey, E. B.; Olm, M. R.; Kothe, C. I.; Evans, J.; Sonnenburg, J. L.

10.1101/2024.03.29.587370 — microbiology — Posted on 2024-03-29

277 Effect of shipping on the microbiome of donor mice used to reconstitute germ-free recipients

McAdams, Z. L.; Yates, J.; Turner, G.; Dorfmeyer, R.; Wight-Carter, M.; Amos-Landgraf, J. M.; Franklin, C. L.; Ericsson, A. C.

10.1101/2024.03.29.587359 — microbiology — Posted on 2024-03-29

278 Co-occurrence of Direct and Indirect Extracellular Electron Transfer Mechanisms during Electroactive Respiration in a Dissimilatory Sulfate Reducing Bacterium

Hou, L.; Cortez, R.; Hagerman, M.; Hu, Z.; Majumder, E. L.- W.

10.1101/2024.03.28.587247 — microbiology — Posted on 2024-03-29

279 Three Modes of Viral Adaption by the Heart

Griffiths, C. D.; Shah, M.; Shao, W.; Borgman, C. A.; Janes, K. A.

10.1101/2024.03.28.587274 — systems biology — Posted on 2024-03-29

280 The PIN2 ortholog in barley modifies root gravitropism and architecture without impacting the shoot

Aldiss, Z.; Robinson, H.; Lam, Y.; Dixon, R.; Crisp, P. A.; Godwin, I. D.; Borrell, A.; Hickey, L.; Massel, K.

10.1101/2024.03.28.587117 — plant biology — Posted on 2024-03-29

281 Effects of ethyl acetate fraction of Psychotria vogeliana leaf on liver function, kidney function, and cytokines level of induced rheumatoid arthritis in albino rats

EZEAN, N. N.; O Ogbu, C. O.; Aja, P. M.; Uti, D. E.; Uche, O. O.; Agu, P. C.; Zakari, S.; Zakari, H.; Awoke, J. N.; Offor, C. E.

10.1101/2024.03.28.587315 — biochemistry — Posted on 2024-03-29

282 Characterization of Arabidopsis aldolases AtFBA4 and AtFBA5; inhibition by morin and interaction with calmodulin

Symonds, K.; Smith, M.; Esme, O.; Plaxton, W.; Snedden, W. A.

10.1101/2024.03.29.587371 — biochemistry — Posted on 2024-03-29

283 Open Educational Resources for distributed hands-on teaching in molecular biology

Cerda Rojas, A.; Aravena, A.; Arce, A.; Zapata, V.; Araya, W.; Gallardo, D.; Aviles, J.; Quero, F.; Nunez, I.; Matute, T.; Navarro, F.; Ferrando, V.; Blanco, M.; Velozo, S.; Aguilera, S.; Chateau, F.; Molloy, J. C.; Aidelberg, G.; Lindner, A. B.; Castro, F.; Cremades, P.; Ramirez-Sarmiento, C. A.; Federici, F.

10.1101/2024.03.28.587173 — molecular biology — Posted on 2024-03-29

284 The ER-phagy receptor FAM134B is targeted by Salmonella Typhimurium to promote infection

Gatica, D.; Alsaadi, R. M.; El Hamra, R.; Mueller, R.; Miyazaki, M.; Sad, S.; Russell, R.

10.1101/2024.03.28.587227 — molecular biology — Posted on 2024-03-29

285 Microbiome of psyllids of the family Aphalaridae, including Aphalara itadori, a potential biocontrol agent against Reynoutria spp.

Nishino, K.; Inoue, H.; Hirose, Y.; Nakabachi, A.

10.1101/2024.03.28.587303 — molecular biology — Posted on 2024-03-29

286 Extended longevity of termite kings and queens is accompanied by extranuclear localization of telomerase in somatic organs and caste-specific expression of its isoforms

Pangracova, M.; Krivanek, J.; Vrchotova, M.; Sehadova, H.; Hadravova, R.; Hanus, R.; Luksan, O.

10.1101/2024.03.28.587005 — molecular biology — Posted on 2024-03-29

287 Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin

Wang, Z.; Zhu, J.; Wang, Y.; Chen, S.; Xu, S.; Li, Y.; Hu, T.; Li, Y.; Wang, X.; Ji, R.; Li, S. C.; Yang, Y.; Jia, H.; Chen, X.; Fan, X.; Ge, L.; Zhang, J.

10.1101/2024.03.28.587170 — molecular biology — Posted on 2024-03-29

288 CORONATINE INSENSITIVE 1-mediated repression of immunity-related genes in Arabidopsis roots is overcome upon infection with Verticillium longisporum

Ulrich, L.; Schmitz, J.; Thurow, C.; Gatz, C.

10.1101/2024.03.27.586993 — molecular biology — Posted on 2024-03-29

289 Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response

Fan, J.; Dhingra, N.; Yang, T.; Yang, V.; Zhao, X.

10.1101/2024.03.28.587206 — molecular biology — Posted on 2024-03-29

290 Broad-Spectrum Coronavirus Inhibitors Discovered by Modeling Viral Fusion Dynamics

Reilly, C. B.; Moore, J.; Lightbown, S.; Paul, A. J.; Bernier, S. G.; Carlson, K. E.; Ingber, D. D.

10.1101/2024.03.28.587229 — microbiology — Posted on 2024-03-29

291 Plasmodium falciparum disruption of pericyte angiopoietin-1 secretion contributes to barrier breakdown in a 3D brain microvessel model

Long, R. K. M.; Korbmacher, F.; Ronchi, P.; Fleckenstein, H.; Mirza, W.; Mallorqui, M.; Aguilar, R.; Moncunill, G.; Schwab, Y.; Bernabeu, M.

10.1101/2024.03.29.587334 — microbiology — Posted on 2024-03-29

292 HIV-1 Capsid Rapidly Induces Long Lived CPSF6 Puncta in Non-dividing Cells but Similar Puncta Already Exist in Uninfected T-cells

Guedan, A.; Burley, M.; Caroe, E.; Bishop, K. N.

10.1101/2024.03.29.587340 — microbiology — Posted on 2024-03-29

293 Enhanced mucosal B- and T-cell responses against SARS-CoV-2 after heterologous intramuscular mRNA prime/intranasal protein boost vaccination with a combination adjuvant.

Laghlali, G.; Wiest, M. J.; Karada, D.; Warang, P.; O'Konek, J. J.; Chang, L. A.; Park, S.; Farazuddin, M.; Landers, J. J.; Janczak, K. W.; Garcia-Sastre, A.; Baker, J. R.; Wong, P. T.; Schotsaert, M.

10.1101/2024.03.28.587260 — immunology — Posted on 2024-03-29

294 SKP2-mediated FBXO2 proteasomal degradation drives hepatocellular carcinoma progression via stabilizing Hsp47

Xue, C.; Yang, F.; Bao, G.; Yan, J.; Fu, R.; Zhang, M.; Ding, J.; Feng, J.; Han, J.; Qin, X.; Su, H.; Sun, B.

10.1101/2024.03.28.586926 — cancer biology — Posted on 2024-03-29

295 Origins of noise in both improving and degrading decision making

Shen, B.; Wilson, J. M.; Nguyen, D.; Glimcher, P. W.; Louie, K.

10.1101/2024.03.26.586597 — neuroscience — Posted on 2024-03-29

296 Assessing Spns2-dependent S1P Transport as a Prospective Therapeutic Target using a New Chemical Probe

Lynch, K. R.; Kharel, Y.; Huang, T.; Dunnavant, K.; Foster, D.; Santos, W.; Xu, W.; Gaultier, A.; Merchak, A.; Leitinger, N.; Pavelec, C.; Abbott, S. B.; Souza, G. M.; Nimchuk, K. T.; Shin, J.-B.

10.1101/2024.03.26.586765 — pharmacology and toxicology — Posted on 2024-03-29

297 Particulate matter constituents trigger the formation of extracellular amyloid beta and Tau-containing plaques and neurite shortening in vitro

Sebastijanovic, A.; Camassa, L. M. A.; Malmborg, V.; Kralj, S.; Pagels, J.; Vogel, U.; Zienolddiny-Narui, S.; Urbancic, I.; Koklic, T.; Strancar, J.

10.1101/2024.03.27.586796 — pharmacology and toxicology — Posted on 2024-03-29

298 The Hyaluronan Synthase isoforms direct distinct patterns of fibroblast activation linked to fibrosis progression versus resolution following renal ischaemia

Grigorieva, I.; Midgley, A.; Brown, C.; Chavez, G.; Williams, A.; Manetta-Jones, D.; Bowen, T.; Chan, D.; Plaas, A.; Chavez, R.; Steadman, R.; Khalid, U.; Meran, S.

10.1101/2024.03.27.586996 — pathology — Posted on 2024-03-29

299 Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons

Fugon, O. J. G.; Sharifi, O.; Heath, N. G.; Soto, D. C.; Gomez, J. A.; Yasui, D. H.; Mendiola, A. J. P.; O'Geen, H.; Beitnere, U.; Tomkova, M.; Haghani, V.; Dillon, G.; Segal, D. J.; LaSalle, J.

10.1101/2024.03.26.586689 — genetics — Posted on 2024-03-29

300 Exhaustion profile on classical monocytes after LPS stimulation in patients with Crohn's disease.

Oliveira, L. P.; Xavier, R. G.; Nora, C. C.; Mangueira, C. L.; Rosseto, E. A.; Aloia, T.; Gil, J. Z.; Scavanini Neto, A.; Lopes, F. B.; Carvalho, K. I.

10.1101/2024.03.28.587307 — immunology — Posted on 2024-03-29

301 Role of the NOS-cGMP pathways in time-dependent sensitization of behavioral responses in zebrafish

de Souza, E. B.; Heymbeeck, J. A. A.; Feitosa, L. M.; Xavier, A. G. O.; Almeida, C. E. d. S.; da Cruz, E. V.; Campos, K. d. S.; dos Santos Rodrigues, L. d. S.; de Freitas, L. M.; da Silva Brito, M. G.; do Carmo Silva, R. X.; Torres, S. L. d. P.; Ikeda, S. R.; Silva, S. d. N. d. S.; Rocha, S. P.; Brito Dias, T. P.; do Nascimento, W. L.; Moraes, E. R. d. S.; Herculano, A. M.; Maximino, C.; Pereira, A.; Lima-Maximino, M.

10.1101/2024.03.27.586937 — neuroscience — Posted on 2024-03-29

302 Selective regulation of corticostriatal synapses by astrocytic phagocytosis

Kim, J.-y.; Lee, H.; Chung, W.-S.; Park, H.

10.1101/2024.03.26.586775 — neuroscience — Posted on 2024-03-29

303 Navigating Human Astrocyte Differentiation: Direct and Rapid one-step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network development

Schuurmans, I. M. E.; Mordelt, A.; Linda, K.; Puvogel, S.; Duineveld, D.; Hommersom, M. P.; Rahm, L.; Dyke, E.; Scholten, G.-J.; Knorz, C.; Oudakker, A.; van Bokhoven, H.; de Witte, L. D.; van Karnebeek, C. D. M.; Garanto, A.; Kasri, N. N.

10.1101/2024.03.27.586938 — neuroscience — Posted on 2024-03-29

304 Sustained ON alpha retinal ganglion cells in the temporal retina exhibit task-specific regional adaptions in dendritic signal integration

Oesterle, J.; Ran, Y.; Stahr, P.; Kerr, J. N.; Schubert, T.; Berens, P.; Euler, T.

10.1101/2024.03.27.586958 — neuroscience — Posted on 2024-03-29

305 Evidence for flexible motor costs in vertical arm movements: reduced gravity-related effort minimization under high accuracy constraints

Poirier, G.; De Filippis, D.; Sirandre, C.; Papaxanthis, C.; Gaveau, J.

10.1101/2024.03.27.586943 — neuroscience — Posted on 2024-03-29

306 ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration

Pourshafie, N.; Xu, H.; Yang, K.; Donahue, G.; Lei, X.; Zhang, S.; Shcherbakova, O.; Hogan, C.; Gilbert, M.; Hoxha, K.; Chanoub, L.; Lee, V.; Adams, P.; Dani, J. A.; Bonini, N. M.; Berger, S. L.

10.1101/2024.03.27.586865 — neuroscience — Posted on 2024-03-29

307 GABAAR-PPT1 palmitoylation homeostasis controls synaptic transmission and circuitry oscillation in CLN1 disease

Ge, L.; Tong, J.; Gao, J.; Qi, Y.; Gao, Z.; Liu, Y.; Wang, Q.; Yuan, T.; Ren, M.; Yang, G.; Li, Z.; Li, J.; Sun, H.; Zhao, X.; Li, J.; Leung, Y.-Y.; Mu, Y.; Xu, J.; Lu, C.; Peng, S.

10.1101/2024.03.26.585929 — neuroscience — Posted on 2024-03-29

308 Quantitative differences in anaerobic growth and metabolism of three different E. coli strains using 13C-Metabolic Flux Analysis

Pachauri, P.; Desai, T.; Ahmad, A.; Srivastava, S.

10.1101/2024.03.27.586947 — systems biology — Posted on 2024-03-29

309 Identifying the gene responsible for NPQ reversal in Phaeodactylum tricornutum

Ware, M. A.; Paton, A.; Bai, Y.; Kassaw, T.; Lohr, M.; Peers, G.

10.1101/2024.03.27.587055 — plant biology — Posted on 2024-03-29

310 Daily Rhythms in Metabolic and Locomotor Behaviour of Prematurely Ageing PolgA Mice

Mueller, R.; Singh, A.; Kuhn, G. A.; Wehrle, E.; Yilmaz, D.

10.1101/2024.03.27.586233 — physiology — Posted on 2024-03-29

311 Reliable estimates of Japanese encephalitis virus evolutionary rate supported by a formal test of temporal signal

Ukraintceva, P. I.; Bondaryuk, A. N.; Sakhabeev, R. G.

10.1101/2024.03.27.586903 — bioinformatics — Posted on 2024-03-29

312 A Comprehensive Model of Blood Flow Restriction in the Post-surgical Rat

Fosam, A.; Nakandakari, S. C. B. R.; Ohashi, Y.; Bai, H.; O'Connell, J.; Raines, A.; Chavez Miranda, I.; Dardik, A.; Allen, C.; Perry, R. J.

10.1101/2024.03.27.586962 — animal behavior and cognition — Posted on 2024-03-29

313 GenoTools: An Open-Source Python Package for Efficient Genotype Data Quality Control and Analysis

Vitale, D.; Koretsky, M.; Kuznetsov, N.; Hong, S.; Martin, J.; James, M.; Makarious, M. B.; Leonard, H.; Iwaki, H.; Faghri, F.; Blauwendraat, C.; Singleton, A. B.; Song, Y.; Levine, K.; Sreelatha, A. A. K.; Fang, Z.-H.; Nalls, M. A.

10.1101/2024.03.26.586362 — genomics — Posted on 2024-03-29

314 Mixed Wolbachia infections resolve rapidly during in vitro evolution

Mirchandani, C.; Wang, P.; Jacobs, J.; Genetti, M.; Pepper-Tunick, E.; Sullivan, W. T.; Corbett-Detig, R.; Russell, S. L.

10.1101/2024.03.27.586911 — evolutionary biology — Posted on 2024-03-29

315 Intramuscular prime/intranasal boost vaccination to induce sterilizing immunity against influenza A virus infection

Avanthay, R.; Garcia-Nicolas, O.; Ruggli, N.; Grau-Roma, L.; Parraga-Ros, E.; Summerfield, A.; Zimmer, G.

10.1101/2024.03.27.586965 — immunology — Posted on 2024-03-29

316 An adverse rearing environment alters maternal responsiveness to infant ultrasonic vocalizations

Rekapalli, A.; Roman, I.; Brenhouse, H. C.; Cody, C. R.

10.1101/2024.03.26.586776 — neuroscience — Posted on 2024-03-29

317 Measuring the time-dependent effects of dobutamine on the modulations of cardiac activity in rats

Candia-Rivera, D.; Carrion-Falgarona, S.; De Vico Fallani, F.; Chavez, M.

10.1101/2024.03.27.586625 — neuroscience — Posted on 2024-03-29

318 Formation and Retrieval of Cell Assemblies in a Biologically Realistic Spiking Neural Network Model of Area CA3 in the Mouse Hippocampus

Kopsick, J. D.; Kilgore, J. A.; Adam, G. C.; Ascoli, G. A.

10.1101/2024.03.27.586909 — neuroscience — Posted on 2024-03-29

319 Plasma Proteomics of Genetic Brain Arteriosclerosis and Dementia Syndrome Identifies Signatures of Fibrosis, Angiogenesis, and Metabolic Alterations

Keller, J. N.; Radabaugh, H.; Karvelas, N.; Fitzsimons, S.; Treiman, S.; Palafox, M. F.; McDonnell, L.; Quiroz, Y. T.; Lopera, F. J.; Banerjee, D.; Wang, M. M.; Arboleda-Velasquez, J. F.; Meschia, J. F.; Ferguson, A. R.; Elahi, F. M.

10.1101/2024.03.28.587249 — neuroscience — Posted on 2024-03-29

320 An EEG Signature of MCH Neuron Activities Predicts Cocaine Seeking

Wang, Y.; Li, D.; Widjaja, J.; Guo, R.; Cai, L.; Yan, R.; Ozsoy, S.; Allocca, G.; Fang, J.; Dong, Y.; Tseng, G. C.; Huang, C.; Huang, Y. H.

10.1101/2024.03.27.586887 — neuroscience — Posted on 2024-03-29

321 Junctional Adhesion Molecule (JAM)-C recruitment of Pard3 and drebrin to cell contacts initiates neuron-glia recognition and layer-specific cell sorting in developing cerebella.

Hallada, L. P.; Shirinifard, A.; Solecki, D. J.

10.1101/2024.03.26.586832 — neuroscience — Posted on 2024-03-29

322 Single nucleus RNA-sequencing reveals transcriptional synchrony across different relationships

Brusman, L. E.; Fultz, A. C.; Dowell, R. D.; Allen, M. A.; Donaldson, Z. R.

10.1101/2024.03.27.587112 — neuroscience — Posted on 2024-03-29

323 Astrocytic metabolic control of orexinergic activity in the lateral hypothalamus regulates sleep and wake architecture

Chiacchiaretta, M.; Haydon, P.; Braga, A.; Pellerin, L.; Kong, D.

10.1101/2024.03.27.586959 — neuroscience — Posted on 2024-03-29

324 Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration

Xu, J.; Hoerner, M.; Nagel, M.; Korneck, M.; Noss, M.; Hauser, S.; Schoels, L.; Admard, J.; Casadei, N.; Schuele, R.

10.1101/2024.03.26.586780 — neuroscience — Posted on 2024-03-29

325 Beyond Accuracy: Refining Brain-Age Models for Enhanced Disease Detection

Schulz, M.-A.; Siegel, N. T.; Ritter, K.

10.1101/2024.03.28.587212 — neuroscience — Posted on 2024-03-29

326 Construction of Animal Models Based on Exploring Pathological Features and Mechanisms of Different Locations in the Progression of DVT-APTE-CTEPD/CTEPH

Huang, L. Q.; Feng, W. W.; Yun, C. X.; Xiang, L. J.; Nan, S.; Xia, W. Q.; Yue, L. X.; He, C. M.; Min, C.; Jing, W. Y.; Wen, W. D.; Li, L. H.; Ran, Y. P.; Xia, Z. Y.; Zhu, Z.; Guo, Z. Z.; Sheng, D. C.

10.1101/2024.03.28.587300 — zoology — Posted on 2024-03-29

327 Ergasilid copepods in Africa: first application of next-generation sequencing and update on distribution and phylogenetic position of Ergasilus kandti, a parasite of cichlid fishes

Jansen, D.; Vanhove, M. P. M.; Makasa, L.; Vorel, J.; Kmentova, N.; Cruz-Laufer, A. J.

10.1101/2024.03.27.586948 — zoology — Posted on 2024-03-29

328 Mitochondrial respiration atlas reveals differential changes in mitochondrial function across sex and age

Sarver, D. C.; Saqib, M.; Chen, F.; Wong, G. W.

10.1101/2024.03.26.586781 — systems biology — Posted on 2024-03-29

329 Evidence that the monoamine oxidase B (MAO-B) plays a central role in the inotropic dysfunction induced by genetic deletion of the Mas-related-G protein-coupled receptor D (MrgD) in mice

Rodrigues-Ribeiro, L.; Rezende-Ribeiro, J.; Scalzo, S.; Dias-Pinto, M. L.; Sanches, B. d. L.; Eliezeck, M.; de Jesus, I. C.; Evaristo, J. A. M.; Sampaio, K. H.; Peruchetti, D. B.; Cruz, J. S.; Nogueira, F. C. S.; Campagnole-Santos, M. J.; Guatimosim, S.; Santos, R. A. S.; Verano-Braga, T.

10.1101/2024.03.27.586916 — physiology — Posted on 2024-03-29

330 Increased TRPV4 channel expression enhances and impairs blood vessel function in hypertension

Zhang, X.; Buckley, C.; Lee, M. D.; MacDonald, M.; Wilson, C.; McCarron, J. G.

10.1101/2024.03.27.587031 — physiology — Posted on 2024-03-29

331 Airway succinate chemosensing induces CFTR-dependent anion secretion and mucus clearance which is impaired in cystic fibrosis.

Apablaza, T.; Barros-Poblete, M.; Delpiano, L.; Villanueva, S.; Guequen, A.; Tapia-Balladares, B.; Haq, I. J.; Tribinos, F.; Hernandez-Rivas, S.; Verdon, B.; Biggart, M. G.; Sanchez, Y.; Ward, C.; Baxter, B. D.; Restrepo, D.; Cornejo, I.; Tarran, R.; Catalan, M. A.; Gray, M.; Flores, C. A.

10.1101/2024.03.26.586799 — physiology — Posted on 2024-03-29

332 Comparative network pharmacology of artificial sweeteners to understand Its health consequences.

Tankala, G.; Kumar, A. H.

10.1101/2024.03.29.587332 — pharmacology and toxicology — Posted on 2024-03-29

333 Leveraging integrative toxicogenomic approach towards development of stressor-centric adverse outcome pathway networks for plastic additives

Sahoo, A. K.; Chivukula, N.; Madgaonkar, S. R.; Ramesh, K.; Marigoudar, S. R.; Sharma, K. V.; Samal, A.

10.1101/2024.03.27.586984 — pharmacology and toxicology — Posted on 2024-03-29

334 DigiLoCS: A Leap Forward in Predictive Organ-on-Chip Simulations

Aravindakshan, M. R.; Mandal, C.; Pothen, A.; Maass, C.

10.1101/2024.03.28.587123 — pharmacology and toxicology — Posted on 2024-03-29

335 Biologically Interpretable VAE with Supervision for Transcriptomics Data Under Ordinal Perturbations

Niyakan, S.; Luo, X.; Yoon, B.-J.; Qian, X.

10.1101/2024.03.28.587231 — bioinformatics — Posted on 2024-03-29

336 Estimation of Jacquard's genetic identity coefficients with bi-allelic variants by constrained least-squares

Graffelman, J.; Weir, B.; Goudet, J.

10.1101/2024.03.25.586682 — genetics — Posted on 2024-03-29

337 A geographic history of human genetic ancestry

Grundler, M. C.; Terhorst, J.; Bradburd, G. S.

10.1101/2024.03.27.586858 — genetics — Posted on 2024-03-29

338 Nest construction and its effect on post-hatching family life in the burying beetle Nicrophorus vespilloides

Bladon, E. K.; Kilner, R. M.

10.1101/2024.03.29.587327 — evolutionary biology — Posted on 2024-03-29

339 Hemoglobin gene repertoire in teleost and cichlid fishes shaped by gene duplications and genome rearrangements

Omelchenko, D.; Bitja-Nyom, A. R.; Matschiner, M.; Malinsky, M.; Indermaur, A.; Salzburger, W.; Bartos, O.; Musilova, Z.

10.1101/2024.03.26.586788 — evolutionary biology — Posted on 2024-03-29

340 Geographic variation in vulnerability to warming temperatures in an intertidal barnacle species

Gilman, S.; Ober, G. T.; Rognstad, R. L.; Bunnenberg-Ross, M.; Man, T.

10.1101/2024.03.26.586848 — ecology — Posted on 2024-03-29

341 Development and Application of Decontamination Methods for the Re-Use of Laboratory Grade Plastic Pipette Tips

Lee, S. H.; Kastor, W.; Fu, X.; Soni, V.; Keidar, M.; Donohue, M.; Wood, S.; Karunasena, E.

10.1101/2024.03.27.587071 — molecular biology — Posted on 2024-03-29

342 Plasma cell heterogeneity is driven by type of immune challenge

Khamyath, M.; Lereclus, E.; Gourhand, V.; Debureaux, P.-E.; Moulin, C.; Gary, H.; Bachelerie, F.; Balabanian, K.; Espeli, M.; Bonaud, A.

10.1101/2024.03.26.586773 — immunology — Posted on 2024-03-29

343 ZFAND6 is a subunit of a TRAF2-cIAP E3 ubiquitin ligase complex essential for mitophagy

Shaikh, K.; Bowman, M.; McCormick, S. M.; Gao, L.; Zhang, J.; Tawil, J.; Kapoor, A.; Arav-Boger, R.; Choi, Y. B.; Pekosz, A.; Klein, S. L.; Lanza, M.; Fanburg-Smith, J. C.; Garcia-Sastre, A.; Norbury, C. C.; Chroneos, Z.; Harhaj, E. W.

10.1101/2024.03.27.586763 — immunology — Posted on 2024-03-29

344 Cytosolic sodium accumulation is a cellular danger signal triggering endocytic dysfunction and NLRP3 inflammasome activation

Mangan, M. S. J.; Akbal, A.; Rivara, S.; Horvath, G. L.; Walch, P.; Hegermann, J.; Kaiser, R.; Duthie, F.; Selkrig, J.; Gerhard, R.; Wachten, D.; Latz, E.

10.1101/2024.03.26.586774 — immunology — Posted on 2024-03-29

345 Heterogeneity of morphometric similarity networks in health and schizophrenia

Janssen, J.; Gallego, A. G.; Diaz-Caneja, C. M.; Lois, N. G.; Janssen, N.; Gonzalez-Penas, J.; Macias, P.; Buimer, E.; van Haren, N.; Arango, C.; Kahn, R.; Hulshoff Pol, H.; Schnack, H.

10.1101/2024.03.26.586768 — neuroscience — Posted on 2024-03-29

346 Enhanced Place Specificity of the Parallel Auditory Brainstem Response: An Electrophysiological Study

Stoll, T. J.; Maddox, R. K.

10.1101/2024.03.10.584313 — neuroscience — Posted on 2024-03-29

347 Prevalent co-release of glutamate and GABA throughout the mouse brain

Ceballos, C. C.; Ma, L.; Qin, M.; Zhong, H.

10.1101/2024.03.27.587069 — neuroscience — Posted on 2024-03-29

348 A novel GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 13 is involved in the Phosphate starvation-induced lipid remodeling in rice

Dang, D. T. T.; Nguyen, L. T.; Tran, T. A.; Tran, T. T. T.; Tran, A. T.; Vo, K. T. X.; Jeon, J.-S.; Vu, T. V.; Kim, J.-Y.; Nguyen, N. P.; Chu, H. H.; Do, P. T.; To, H. T. M.

10.1101/2024.03.27.586571 — plant biology — Posted on 2024-03-29

349 Panax ginseng enhances the effect of metoprolol in chronic heart failure by inhibiting autophagy

Zichang, N.; Xiaoling, H.; Ting, L.; Qi, J.; Minghui, O.; Mao, H.

10.1101/2024.03.26.586847 — pharmacology and toxicology — Posted on 2024-03-29

350 Rampant transcription replication conflict creates therapeutic vulnerability in extrachromosomal DNA containing cancers

Tang, J.; Weiser, N. E.; Wang, G.; Chowdhry, S.; Curtis, E. J.; Zhao, Y.; Wong, I. T.-L.; Marinov, G. K.; Li, R.; Hanoian, P.; Tse, E.; Hansen, R.; Plum, J.; Steffy, A.; Milutinovic, S.; Meyer, S. T.; Altemose, N.; Curtis, C.; Greenleaf, W. J.; Bafna, V.; Benkovic, S. J.; Pinkerton, A. B.; Kasibhatla, S.; Hassig, C. A.; Mischel, P. S.; Chang, H. Y.

10.1101/2024.03.29.586681 — cancer biology — Posted on 2024-03-29

351 Real-time transcriptomic profiling in distinct experimental conditions

Butto, T.; Pastore, S.; Mueller, M.; Iyer, K. V.; Muendnich, S.; Wierczeiko, A.; Friedland, K.; Helm, M.; Winz, M.-L.; Gerber, S.

10.1101/2024.03.26.586831 — bioinformatics — Posted on 2024-03-29

352 Cellects, a software to quantify cell expansion and motion

Boussard, A.; Arrufat, P.; Dussutour, A.; Perez-Escudero, A.

10.1101/2024.03.26.586795 — bioinformatics — Posted on 2024-03-29

353 AdjuSST: An Adjustable Surface Stiffness Treadmill

Price, M. A.; Locurto, D.; Abdikadirova, B.; Huber, M. E.; Hoogkamer, W.

10.1101/2024.03.25.586685 — bioengineering — Posted on 2024-03-29

354 Deep postnatal phenotyping of a new mouse model of nonketotic hyperglycinemia

Swanson, M. A.; Jiang, H.; Busquet, N.; Carlsen, J.; Brindley, C.; Benke, T. A.; Van Hove, R. A.; Friederich, M. W.; MacLean, K. N.; Mesches, M. A.; Van Hove, J. L.

10.1101/2024.03.26.586818 — animal behavior and cognition — Posted on 2024-03-29

355 Completion of the DrugMatrix Toxicogenomics Database using ToxCompl

Cong, G.; Patton, R. M.; Chao, F.; Svoboda, D. L.; Casey, W. M.; Schmitt, C. P.; Murphy, C.; Erickson, J. N.; Combs, P. A.; Auerbach, S. S.

10.1101/2024.03.26.586669 — genomics — Posted on 2024-03-29

356 Please Mind the Gap: Indel-Aware Parsimony for Fast and Accurate Ancestral Sequence Reconstruction and Multiple Sequence Alignment including Long Indels

Iglhaut, C.; Pecerska, J.; Gil, M.; Anisimova, M.

10.1101/2024.03.27.586611 — genomics — Posted on 2024-03-29

357 Widespread transcription initiation within coding sequences marks tissue identity and accessible chromatin

Wang, X.; Duan, J.; Clark, C. B.; Feng, W.; Ma, J.

10.1101/2024.03.27.587116 — genomics — Posted on 2024-03-29

358 Two highly selected mutations in the tandemly duplicated CYP6P4a and CYP6P4b drive pyrethroid resistance in Anopheles funestus

Tatchou-Nebangwa, N. M. T.; Mugenzi, L. M. J.; Muhammad, A.; Nebangwa, D. N.; Kouamo, M. F. M.; Tagne, C. S. D.; Tekoh, T. A.; Tchouakui, M.; Ghogomu, S. M.; Ibrahim, S. S.; Wondji, C. S.

10.1101/2024.03.26.586794 — genetics — Posted on 2024-03-29

359 Human ancestry inference at scale, from genomic data

Warren, R. L.; Coombe, L.; Wong, J.; Kazemi, P.; Birol, I.

10.1101/2024.03.26.586646 — genetics — Posted on 2024-03-29

360 Collective anti-predator escape manoeuvres through optimal attack and avoidance strategies

Bartashevich, P.; Herbert-Read, J. E.; Hansen, M. J.; Dhellemmes, F.; Domenici, P.; Krause, J.; Romanczuk, P.

10.1101/2024.03.26.586812 — ecology — Posted on 2024-03-29

361 Extracellular vesicle-mediated secretion of chlorophyll biosynthetic intermediates in the cyanobacterium Leptolyngbya boryana

Usui, K.; Yamamoto, H.; Mori, H.; Fujita, Y.

10.1101/2024.03.29.587320 — microbiology — Posted on 2024-03-29

362 MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

Graca, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.

10.1101/2024.03.26.586840 — microbiology — Posted on 2024-03-29

363 De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assemblies

Beaulaurier, J.; Ly, L.; Duty, J. A.; Tyer, C.; Stevens, C.; Hung, C.-t.; Sookdeo, A.; Drong, A. W.; Kowdle, S.; Turner, D. J.; Juul, S.; Hickey, S.; Lee, B.

10.1101/2024.03.26.586834 — immunology — Posted on 2024-03-29

364 Butyrate and propionate are microbial danger signals that activate the NLRP3-inflammasome in human macrophages in the presence of TLR stimulation

Wang, W.; Dernst, A.; Martin, B.; Lorenzi, L.; Phulphagar, K.; Wagener, A.; Budden, C.; Stair, N.; Wagner, T.; Faerber, H.; Jaensch, A.; Stahl, R.; Duthie, F.; Schmidt, S. V.; Coll, R. C.; Meissner, F.; Cuartero, S.; Mangan, M. S. J.; Latz, E.

10.1101/2024.03.26.586782 — immunology — Posted on 2024-03-29

365 Holding glycolysis in check though Alox15 activity is required for macrophage M2 commitment and function in tissue repair and anti-helminth immunity.

Doolan, R.; Moyat, m.; Coakley, G.; Wickramasinghe Mudiyansel, L.; Daunt, C.; Volpe, B.; Henkel, F.; Trefzer, V.; Ubags, N.; Butler, A.; Chatzis, R.; Marsland, B.; Smith, A. A. T.; Deveson, D. L.; McGowan, E. N. S.; Binger, K. J.; Esser-von Bieren, J.; Bouchery, T.; Harris, N.

10.1101/2024.03.26.586755 — immunology — Posted on 2024-03-29

366 EEG biomarkers of GABA α5 positive allosteric modulators in rodents

Mazza, F.; Guet-McCreight, A.; Prevot, T. D.; Valiante, T. A.; Sibille, E.; Hay, E.

10.1101/2024.03.26.586837 — neuroscience — Posted on 2024-03-29

367 Robust encoding of sub-sniff temporal information in the mouse olfactory bulb

Warner, T. P. A.; Tootoonian, S.; Schaefer, A. T.

10.1101/2024.03.26.586830 — neuroscience — Posted on 2024-03-29

368 The Interplay Between Multisensory Processing and Attention in Working Memory: Behavioral and Neural Indices of Audio-Visual Object Storage

Arslan, C.; Schneider, D.; Getzmann, S.; Wascher, E.; Klatt, L.-I.

10.1101/2024.03.26.586805 — neuroscience — Posted on 2024-03-29

369 Sustained bias of spatial attention in a 3T MRI scanner

Smaczny, S.; Behle, L.; Kuppe, S.; Karnath, H.-O.; Lindner, A.

10.1101/2024.03.26.586826 — neuroscience — Posted on 2024-03-29

370 Retinotopic biases in contextual feedback signals to V1 for object and scene processing

Bennett, M. A.; Petro, L. S.; Abbatecola, C.; Muckli, L.

10.1101/2024.03.26.586553 — neuroscience — Posted on 2024-03-29

371 Model-based frequency-and-phase correction of 1H MRS data with 2D linear-combination modeling.

Simicic, D.; Zöllner, H. J.; Davies-Jenkins, C. W.; Hupfeld, K. E.; Edden, R. A. E.; Oeltzschner, G.

10.1101/2024.03.26.586804 — neuroscience — Posted on 2024-03-29

372 Xylazine does not enhance fentanyl reinforcement in rats: a behavioral economic analysis

St. Onge, C.; Canfield, J.; Ortiz, A.; Sprague, J.; Banks, M.

10.1101/2024.02.26.582112 — pharmacology and toxicology — Posted on 2024-03-29

373 A Multiparametric Analysis Reveals Differential Behavior of Spheroid Cultures on Distinct Ultra-Low Attachment Plates Types

Vitacolonna, M.; Bruch, R.; Agaci, A.; Nuernberg, E.; Cesetti, T.; Keller, F.; Padovani, F.; Sauer, S.; Schmoller, K. M.; Reischl, M.; Hafner, M.; Rudolf, R.

10.1101/2024.03.26.586778 — cancer biology — Posted on 2024-03-29

374 Predicting gene expression from histone marks using chromatin deep learning models depends on histone mark function, regulatory distance and cellular states

Murphy, A. E.; Askarova, A.; Lenhard, B. E.; Skene, N. G.; Marzi, S. J.

10.1101/2024.03.29.587323 — genomics — Posted on 2024-03-29

375 Interspecies regulatory landscapes and elements revealed by novel joint systematic integration of human and mouse blood cell epigenomes

Xiang, G.; He, X.; Giardine, B. M.; Isaac, K. J.; Taylor, D. J.; McCoy, R. C.; Jansen, C.; Keller, C. A.; Wixom, A. Q.; Cockburn, A.; Miller, A.; Qi, Q.; He, Y.; Li, Y.; Lichtenberg, J.; Heuston, E. F.; Anderson, S. M.; Luan, J.; Vermunt, M. W.; Yue, F.; Sauria, M. E. G.; Schatz, M. C.; Taylor, J.; Gottgens, B.; Hughes, J. R.; Higgs, D. R.; Weiss, M. J.; Cheng, Y.; Blobel, G. A.; Bodine, D. M.; Zhang, Y.; Li, Q.; Mahony, S.; Hardison, R. C.

10.1101/2023.04.02.535219 — genomics — Posted on 2024-03-29

376 Sex chromosome turnover in African annual killifishes of the genus Nothobranchius

Hospodarska, M.; Mora, P.; Volenikova, A. C.; Al-Rikabi, A.; Simanovsky, S. A.; Pavlica, T.; Altmanova, M.; Janeckova, K.; Stundlova, J.; Tolar, N.; Jankasek, M.; Hirman, M.; Liehr, T.; Reichard, M.; Krysanov, E. Y.; Rab, P.; Englert, C.; Nguyen, P.; Sember, A.

10.1101/2024.03.25.586567 — evolutionary biology — Posted on 2024-03-29

377 Emergent Collective Behavior Evolves More Rapidly Than Individual Behavior Among Ant Species

Doering, G. N.; Prebus, M. M.; Suresh, S.; Greer, J. N.; Bowden, R.; Linksvayer, T. A.

10.1101/2024.03.26.586722 — evolutionary biology — Posted on 2024-03-29

378 Assessment of the efficacy of field and laboratory methods for the detection of Tropilaelaps spp.

Gill, M. C.; Chuttong, B.; Davies, P.; Etheridge, D.; Panyaraksa, L.; Tomkies, V.; Tonge, G.; Budge, G. E.

10.1101/2024.03.26.586849 — ecology — Posted on 2024-03-29

379 Nutrient addition in grasslands worldwide reveals proportional plant diversity decline across spatial scales but little change in beta diversity

Chen, Q.; Blowes, S.; Ladouceur, E.; Harpole, S.; Seabloom, E. W.; Tognetti, P. M.; MacDougall, A.; Daleo, P.; Hautier, Y.; Stevens, C.; Morgan, J.; Veen, C.; Risch, A. C.; Roscher, C.; Bakker, J. D.; Adler, P.; Borer, E.; Niu, Y.; Peri, P. L.; Martina, J.; Eisenhauer, N.; Virtanen, R.; Power, S.; Catford, J.; Tedder, M.; Bagchi, S.; Wheeler, G.; Haider, S.; Maria, C.; Bugalho, M.; Knops, J.; Dickman, C.; Hagenah, N.; Jentsch, A.; Wardle, G.; Estrada, C.; Donohue, I.; Gruner, D.; Olde Venterink, H.; Lannes, L.; Hersch-Green, E.; Chase, J.

10.1101/2024.03.27.586835 — ecology — Posted on 2024-03-29

380 The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration

Zhao, B.; Socha, J.; Fernandes, S.; Warheit-Niemi, H.; Ruff, B.; Hershey, G. K. K.; VanDussen, K. L.; Swarr, D. T.; Zacharias, W. J.

10.1101/2024.03.26.586673 — developmental biology — Posted on 2024-03-29

381 Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Le Bozec, B.; Guitton-Sert, L.; Collins, S.; Finoux, A.-L.; Payrault, C.; Frison, J.; Carette, R.; Rocher, V.; Guillou, E.; Arnould, C.; Guenole, A.; Aguirrebengoa, M.; Lazar, I.; Marnef, A.; Frit, P.; Calsou, P.; Mangeat, T.; Puget, N.; Legube, G.

10.1101/2023.05.11.540338 — molecular biology — Posted on 2024-03-29

382 Extensive, transient, and long-lasting gene regulation in a song-controlling brain area during testosterone-induced song development in adult female canaries

Ko, M.-C.; Frankl-Vilches, C.; Bakker, A.; Sohnius-Wilhelmi, N.; Alcami, P.; Gahr, M.

10.1101/2022.06.13.495861 — molecular biology — Posted on 2024-03-29

383 The rise of cheats during experimental evolution is restricted by non-kin interactions between Bacillus subtilis soil isolates

Belcijan Pandur, K.; Kraigher, B.; Tomac, A.; Stefanic, P.; Mandic Mulec, I.

10.1101/2024.03.29.587313 — microbiology — Posted on 2024-03-29

384 M2 macrophages dampen in utero sterile inflammation to prevent preterm birth and improve neonatal outcomes

Garcia-Flores, V.; Liu, Z.; Romero, R.; Xu, Y.; Miller, D.; Galaz, J.; Winters, A. D.; Farias-Jofre, M.; Panzer, J. J.; Theis, K. R.; Gomez-Lopez, N.

10.1101/2023.07.19.549717 — immunology — Posted on 2024-03-29

385 Multitasking practice eliminates modality-based interference by separating task representations in sensory brain regions

Mueckstein, M.; Goergen, K.; Heinzel, S.; Granacher, U.; Rapp, M. A.; Stelzel, C.

10.1101/2024.03.26.586741 — neuroscience — Posted on 2024-03-29

386 Volume Electron Microscopy Analysis of Synapses in Associative and Primary Regions of the Human Cerebral Cortex

Cano-Astorga, N.; Plaza-Alonso, S.; DeFelipe, J. D.; Alonso-Nanclares, L.

10.1101/2024.03.26.586748 — neuroscience — Posted on 2024-03-29

387 Chilean brush tailed mouse (Octodon degus): a diurnal precocial rodent as a new model to study visual receptive field properties of superior colliculus neurons

Marquez, N. I.; Fernandez-Aburto, P. F.; Deichler, A.; Perales, I.; Letelier, J.-C.; Marin, G. J.; Mpodozis, J.; Pallas, S. L.

10.1101/2024.03.25.586655 — neuroscience — Posted on 2024-03-29

388 Senolytic therapy preserves blood-brain barrier integrity and promotes microglia homeostasis in a tauopathy model

Yao, M.; Wei, Z.; Nielsen, J. S.; Kakazu, A.; Ouyang, Y.; Li, R.; Chu, T.; Scafidi, S.; Lu, H.; Aggarwal, M.; Duan, W.

10.1101/2024.03.25.586662 — neuroscience — Posted on 2024-03-29

389 Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice

McFadden, S. A.; Peck, M. R.; Sime, L. N.; Cox, M. F.; Ikiz, E. D.; Findley, C. A.; Quinn, K.; Fang, Y.; Bartke, A.; Hascup, E. R.; Hascup, K. N.

10.1101/2024.03.26.586836 — neuroscience — Posted on 2024-03-29

390 Neurovascular unit adjustments following chronic distress explain motivational deficits in mice

Cabeza, L.; Mor, D.; Ramadan, B.; Benhora-Chabeaux, G.; Houdayer, C.; Haffen, E.; Peterschmitt, Y.; Etievant, A.; Bourasset, F.

10.1101/2024.03.25.586557 — neuroscience — Posted on 2024-03-29

391 Probing enzyme-dependent pseudouridylation using direct RNA sequencing to assess neuronal epitranscriptome plasticity

Fanari, O.; Tavakoli, S.; Akeson, S.; Makhamreh, A.; Nian, K.; McCormick, C. A.; Qiu, Y.; Bloch, D.; Jain, M.; Wanunu, M.; Rouhanifard, S. H.

10.1101/2024.03.26.586895 — systems biology — Posted on 2024-03-29

392 Cortisol levels, heart rate, and autonomic responses in horses during repeated road transport with different truck conditions trucks in a tropical environment

Lertratanachai, S.; Poochipakorn, C.; Sanigavatee, K.; Huangsaksri, O.; Wonghanchao, T.; Charoenchanikran, P.; Lawsirirat, C.; Chanda, M.

10.1101/2024.03.26.586854 — physiology — Posted on 2024-03-29

393 Phosphodiesterase-5 inhibition inhibits epithelial ATP release and restores detrusor contractility in rats with type 2 diabetes via an increase in bladder blood flow

Kabuto, T.; Inamura, S.; Kobayashi, H.; Zha, X.; Nagase, K.; Taga, M.; Seki, M.; Tanaka, N.; Okumura, Y.; Yokoyama, O.; Terada, N.

10.1101/2024.03.26.586851 — pharmacology and toxicology — Posted on 2024-03-29

394 Development of a First-in-Class RIPK1 Degrader to Enhance Antitumor Immunity

Yu, X.; Lu, D.; Wang, J.

10.1101/2024.03.25.586133 — pharmacology and toxicology — Posted on 2024-03-29

395 Simulation of zonation-function relationships in the liver using coupled multiscale models: Application to drug-induced liver injury

Gerhäusser, S.; Lambers, L.; Mandl, L.; Franquinet, J.; Ricken, T.; König, M.

10.1101/2024.03.26.586870 — pharmacology and toxicology — Posted on 2024-03-29

396 Uncovering microstructural architecture from histology

Georgiadis, M.; auf der Heiden, F.; Abbasi, H.; Ettema, L.; Nirschl, J.; Moein Taghavi, H.; Wakatsuki, M.; Liu, A.; Ho, W. H. D.; Carlson, M.; Doukas, M.; Koppes, S. A.; Keereweer, S.; Sobel, R. A.; Setsompop, K.; Liao, C.; Amunts, K.; Axer, M.; Zeineh, M. M.; Menzel, M.

10.1101/2024.03.26.586745 — pathology — Posted on 2024-03-29

397 Loss of Lkb1 cooperates with BrafV600E and UV radiation increasing melanoma multiplicity and neural-like dedifferentiation

McGrail, K. A.; Gonzlez-Sanchez, E.; Granado-Martinez, P.; Orsenigo, R.; Ding, Y.; Ferrer, B.; Hernandez-Losa, J.; Ortega, I.; Martin-Caballero, J.; Munoz-Couselo, E.; Garcia-Patos, V.; Recio, J. A.

10.1101/2024.03.29.587140 — cancer biology — Posted on 2024-03-29

398 Comparison of the tolerability of terbium-161 and lutetium-177 in combination with somatostatin analogues in the preclinical setting

Busslinger, S. D.; Mapanao, A. K.; Kegler, K.; Bernhardt, P.; Fluehmann, F.; Fricke, J.; Zeevaart, J. R.; Koester, U.; van der Meulen, N. P.; Schibli, R.; Mueller, C.

10.1101/2024.03.29.587329 — cancer biology — Posted on 2024-03-29

399 Extracellular vesicles within a tumourigenic therapy-induced senescent tumour secretome are able to confer anti-cancer properties.

Robert, M.; Jakhar, R.; Crasta, K. C.

10.1101/2024.03.29.586905 — cancer biology — Posted on 2024-03-29

400 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; Wang, X.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.

10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-03-29

401 VISION -- an open-source software for automated multi-dimensional image analysis of cellular biophysics

Weber, F.; Iskrak, S.; Ragaller, F.; Schlegel, J.; Plochberger, B.; Sezgin, E.; Andronico, L.

10.1101/2024.03.29.587344 — biophysics — Posted on 2024-03-29

402 Harnessing the Power of Large Language Models (LLMs) to Unravel the Influence of Genes and Medication on Biological Processes of Wound Healing

Jui, J. H.; Hauskrecht, M.

10.1101/2024.03.26.586862 — bioinformatics — Posted on 2024-03-29

403 msqrob2TMT: robust linear mixed models for inferring differential abundant proteins in labelled experiments with arbitrarily complex design

Vandenbulcke, S.; Vanderaa, C.; Crook, O.; Martens, L.; Clement, L.

10.1101/2024.03.29.587218 — bioinformatics — Posted on 2024-03-29

404 Development of AI-assisted microscopy frameworks through realistic simulation in pySTED

Bilodeau, A.; Michaud-Gagnon, A.; Chabbert, J.; Turcotte, B.; Heine, J.; Durand, A.; Lavoie-Cardinal, F.

10.1101/2024.03.25.586697 — bioinformatics — Posted on 2024-03-29

405 Systematic Evaluation of Cell Type Deconvolution Methods for Plasma Cell-free DNA

Sun, T.; Yuan, J.; Zhu, Y.; Yang, S.; Zhou, J.; Ge, X.; Qu, S.; Li, W.; Li, J. J.; Li, Y.

10.1101/2024.03.25.586507 — bioinformatics — Posted on 2024-03-29

406 Mapping the genomic landscape of peach and almond with PrunusMap

Ksouri, N.; Moreno, M. A.; Contreras-Moreira, B.; Gogorcena, Y.

10.1101/2024.03.26.586732 — bioinformatics — Posted on 2024-03-29

407 Inferring Ancestry with the Hierarchical Soft Clustering Approach tangleGen

Burger, K. E.; Klepper, S.; von Luxburg, U.; Baumdicker, F.

10.1101/2024.03.27.586940 — bioinformatics — Posted on 2024-03-29

408 Immediate-Early Genes as Influencers in Genetic Networks and their Role in Alzheimer's Disease

Zachariou, M.; Loizidou, E. M.; Spyrou, G. M.

10.1101/2024.03.29.586739 — bioinformatics — Posted on 2024-03-29

409 HIPI: Spatially Resolved Multiplexed Protein Expression Inferred from H&E WSIs

Zeira, R.; Anavy, L.; Yakhini, Z.; Rivlin, E.; Freedman, D.

10.1101/2024.03.26.586744 — bioinformatics — Posted on 2024-03-29

410 Non-invasive optoacoustic imaging visualizes exercise-induced dermal revascularization in obese mice

Huang, S.; He, H.; Tom, R. Z.; Glasl, S.; Anzenhofer, P.; Stiel, A. C.; Hofmann, S.; Ntziachristos, V.

10.1101/2024.03.26.586767 — bioengineering — Posted on 2024-03-29

411 Rationalizing diverse binding mechanisms to the same protein fold: in-sights for ligand recognition and biosensor design

Leonard, A. C.; Friedman, A. J.; Chayer, R.; Petersen, B. M.; Kaar, J.; Shirts, M. R.; Whitehead, T. A.

10.1101/2024.03.25.586677 — bioengineering — Posted on 2024-03-29

412 Twisting Urea- to Imide-Based Mass Spectrometry-Cleavable Cross-Linkers Enables Affinity Tagging

Di Ianni, A.; Ihling, C. H.; Vranka, T.; Matousek, V.; Sinz, A.; Iacobucci, C.

10.1101/2024.03.29.587196 — biochemistry — Posted on 2024-03-29

413 Nonadjacent Dependencies and Syntactic Structure of Chimpanzee Action During a Natural Tool-Use Task

Howard-Spink, E.; Hayashi, M.; Matsuzawa, T.; Schofield, D.; Gruber, T.; Biro, D.

10.1101/2024.03.25.586385 — animal behavior and cognition — Posted on 2024-03-29

414 Diverse prey capture strategies in teleost larvae

Mearns, D. S.; Hunt, S. A.; Schneider, M. W.; Parker, A. V.; Stemmer, M.; Baier, H.

10.1101/2023.10.03.560453 — animal behavior and cognition — Posted on 2024-03-29

415 Fast exploration is coupled with a less choosy but more reactive learning style in a generalist predator

Kuo, C.-Y.; Chen, Y.-H.; Meng, A.-C.; Wu, Y.-Z.; Yang, S.-Y.; Yeh, C.-N.

10.1101/2024.03.26.586890 — animal behavior and cognition — Posted on 2024-03-29

416 VRPG: an interactive web viewer for reference-projected pangenome graph

Miao, Z.; Yue, J.-X.

10.1101/2023.01.20.524991 — genomics — Posted on 2024-03-29

417 Transposable element expression with variation in sex chromosome number supports a toxic Y effect on human longevity

Teoli, J.; Merenciano, M.; Fablet, M.; Necsulea, A.; Siqueira-de-Oliveira, D.; Brandulas-Cammarata, A.; Labalme, A.; Lejeune, H.; Lemaitre, J.-F.; Gueyffier, F.; Sanlaville, D.; Bardel, C.; Vieira, C.; Marais, G. A.; Plotton, I.

10.1101/2023.08.03.550779 — genomics — Posted on 2024-03-29

418 Skull evolution and lineage diversification in endemic Malagasy carnivorans

Law, C.; Linden, T.; Flynn, J. J.

10.1101/2024.03.25.586658 — evolutionary biology — Posted on 2024-03-29

419 Faster inference of complex demographic models from large allele frequency spectra

Dilber, E.; Terhorst, J.

10.1101/2024.03.26.586844 — evolutionary biology — Posted on 2024-03-29

420 Parent-specific transgenerational immune priming enhances offspring defense - unless heat-stress negates it all

Schneider, R. F.; Dubin, A.; Marten, S.-M.; Roth, O.

10.1101/2024.03.29.587316 — evolutionary biology — Posted on 2024-03-29

421 Emergent predictability in microbial ecosystems

Moran, J.; Tikhonov, M.

10.1101/2024.03.26.586882 — ecology — Posted on 2024-03-29

422 Evaluating Species at Risk in Data-Limited Fisheries: A Comprehensive Productivity-Susceptibility Analysis of the Most Traded Marine Aquarium Fish

Baillargeon, G. A.; Wynn, A. A.; Baldisimo, J. G. P.; Tlusty, M. F.; Rhyne, A. L.

10.1101/2024.03.26.586872 — ecology — Posted on 2024-03-29

423 Maternal characteristics and their relation to early mother-child interaction and cognitive development in toddlers

Preiss, J.; Lang, A.; Hauser, T.; Angerer, M.; Schernhardt, P.; Schabus, M.

10.1101/2024.03.26.586846 — developmental biology — Posted on 2024-03-29

424 In quiescent G0 phase, Schizosaccharomyces pombe Mis4 ensures full nuclear separation during the subsequent M phase

Suma, M.; Arakawa, O.; Tahara, Y.; Sajiki, K.; Saitoh, S.; Yanagida, M.

10.1101/2024.03.29.587322 — cell biology — Posted on 2024-03-29

425 Leiomodin 1 promotes myogenic differentiation by modulating Sirtuin 1

Spath, E.; Schuler, S. C.; Heinze, I.; Dau, T. T. D.; Minetti, A.; Hofmann, M.; von Maltzahn, J.; Ori, A.

10.1101/2024.03.29.587321 — cell biology — Posted on 2024-03-29

426 Multi-compartment impact of micropollutants and particularly antibiotics on bacterial communities using environmental DNA at river basin-level

Inostroza, P. A.; Jessen, G. L.; Li, F.; Zhang, X.; Brack, W.; Backhaus, T.

10.1101/2024.03.28.587215 — microbiology — Posted on 2024-03-29

427 Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance

Seshadri, A.; Badrinarayanan, A.

10.1101/2024.03.29.587326 — microbiology — Posted on 2024-03-29

428 Root-associated Streptomyces produce galbonolides to modulate plant immunity and promote rhizosphere colonisation

Nicolle, C.; Gayrard, D.; Noel, A.; Hortala, M.; Amiel, A.; Grat, S.; Le Ru, A.; Marti, G.; Pernodet, J.-L.; Lautru, S.; Dumas, B.; Rey, T.

10.1101/2024.01.20.576418 — microbiology — Posted on 2024-03-29

429 Metabolic disruption impairs ribosomal protein levels, resulting in enhanced aminoglycoside tolerance

Shiraliyev, R.; Orman, M.

10.1101/2023.12.20.572673 — microbiology — Posted on 2024-03-29

430 CD4+ Trm sustain the chronic phase of auto-immune neuroinflammatory disease

Pignata, A.; Frieser, D.; Hsiao, C.-C.; Engelenburg, H. J.; Alis, M.; Gonzalez-Fierro, C.; Cazaentre, V.; Miranda-Capet, R.; Dufourd, E.; Vermeulen, T.; Aida, A.; Vangisbergen, K.; Blanchard, N.; Hamann, J.; Smolders, J.; Liblau, R.; Masson, F.

10.1101/2024.03.26.586880 — immunology — Posted on 2024-03-29

431 Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response

John, K.; Huntress, I.; Smith, E.; Chou, H.; Tollison, T. S.; Covarrubias, S.; Crisci, E.; Carpenter, S.; Peng, X.

10.1101/2024.03.25.586578 — immunology — Posted on 2024-03-29

432 KIR3DL1 and Tox identify clonally expanded encephalitogenic neuron-specific CD8+ T cells in autoimmune encephalitis

Perriot, S.; Jones, S.; Genolet, R.; Mathias, A.; Lindsay, H.; Bobisse, S.; Di Liberto, G.; Canales, M.; Queiroz, L.; Sauvage, C.; Wagner, I.; Oberholster, L.; Gimenez, M.; Begarie, D.; Theaudin, M.; Pot, C.; Merkler, D.; Gottardo, R.; Harari, A.; Du Pasquier, R.

10.1101/2024.03.25.586688 — immunology — Posted on 2024-03-29

433 Anabolic lipid metabolism regulates adipose type 2 innate lymphoid cell differentiation to maintain metabolic health

Theodorou, M. R.; Yu, J.; Nikolka, F.; Zurkovic, J.; Wientjens, C.; Weiss, P.; Rombo, R.; Karagiannis, F.; Thiele, C.; Hasenauer, J.; Hiller, K.; Wilhelm, C.

10.1101/2024.03.26.586766 — immunology — Posted on 2024-03-29

434 Complement activation by IgG subclasses is governed by their ability to oligomerize upon antigen binding

Frischauf, N.; Strasser, J.; Borg, E. G. F.; Labrijn, A. F.; Beurskens, F. J.; Preiner, J.

10.1101/2024.03.26.586731 — immunology — Posted on 2024-03-29

435 Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1alpha axis plays a key role in host resistance to Plasmodium infection

Matteucci, K. C.; Assis, P. A.; Hirako, I. C.; Leite, N. P. S.; Pioto, F.; OJELABI, O.; E. TOLLER-KAWAHISA, J.; Costa, D. L.; S. Silva, J.; Alves-Filho, J. C.; Gazzinelli, R.

10.1101/2024.03.26.586751 — immunology — Posted on 2024-03-29

436 Thalamic blood flow and EEG frequency band power during hyperventilation in idiopathic generalized epilepsy

Debatisse, J.; Yaakub, S. N.; De Vita, E.; Charles-Edwards, G.; Jeljeli, S.; Stirling, J.; Flaus, A.; Dunn, J.; Koutroumanidis, M.; Hammers, A.; McGinnity, C. J.

10.1101/2024.03.26.586742 — neuroscience — Posted on 2024-03-29

437 MANIPULATING MITOCHONDRIAL REACTIVE OXYGEN SPECIES ALTERS SURVIVAL IN UNEXPECTED WAYS IN A DROSOPHILA MODEL OF NEURODEGENERATION

Wodrich, A. P. K.; Harris, B. T.; Giniger, E.

10.1101/2024.03.25.586603 — neuroscience — Posted on 2024-03-29

438 Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function

Ono, K.; Jarysta, A.; Hughes, N.; Jukic, A.; Chang, V. H. H.; Deans, M. R.; Eatock, R. A.; Cullen, K. E.; Kindt, K. S.; Tarchini, B.

10.1101/2024.03.26.586740 — neuroscience — Posted on 2024-03-29

439 Effects of early life adversity and adolescent basolateral amygdala inhibition on corticolimbic connectivity and anxiety behaviors

Cody, C. R.; Artur de la Villarmois, E.; Auger, M.; Miguelez Fernandez, A.; Lardizaball, J.; McKnight, C.; Tseng, K.; Brenhouse, H. C.

10.1101/2024.03.26.586708 — neuroscience — Posted on 2024-03-29

440 Exploring dynamic brain oscillations in motor imagery and low-frequency sound

Dupont, W.; Poulin-Charronnat, B.; Madden Lombardi, C.; Jacquet, T.; Pfister, P.; Dos Anjos, T.; Lebon, F.

10.1101/2024.03.26.586734 — neuroscience — Posted on 2024-03-29

441 Associations between parenting and cognitive and language abilities at age 2 depend on prenatal exposure to disadvantage

Leverett, S. D.; Brady, R. G.; Tooley, U. A.; Lean, R. E.; Tillman, R.; Wilson, J.; Ruscitti, M.; Triplett, R. L.; alexopoulos, D.; Gerstein, E. D.; Smyser, T. A.; Warner, B.; Luby, J. D.; Smyser, C. D.; Rogers, C. E.; Barch, D. M.

10.1101/2024.03.25.586610 — neuroscience — Posted on 2024-03-29

442 Integrating Optogenetic Stimulation of Olfactory Bulb Glomeruli with Foot Shock Fear Conditioning: A Robust Method for Investigating Olfactory-based Fear Conditioning

Kuruppath, P.

10.1101/2024.03.25.586672 — neuroscience — Posted on 2024-03-29

443 Temporal prediction captures retinal spiking responses across animal species

Taylor, L.; Zenke, F.; King, A. J.; Harper, N. S.

10.1101/2024.03.26.586771 — neuroscience — Posted on 2024-03-29

444 Bayesian Efficient Coding

Park, I. M.; Pillow, J. W.

10.1101/178418 — neuroscience — Posted on 2024-03-29

445 Locus Coeruleus Contrast and Diffusivity: Effects of Age and Relations to Memory

Bennett, I. J.; Langley, J.; Sun, A.; Solis, K.; Seitz, A. R.; Hu, X. P.

10.1101/2024.03.25.586618 — neuroscience — Posted on 2024-03-29

446 Non-canonical adrenergic neuromodulation of motoneuron intrinsic excitability through beta-receptors in wild-type and ALS mice

Antonucci, S.; Caron, G.; Dikwella, N.; Krishnamurthy, S. S.; Zarrin, H.; Tahanis, A.; Olde Heuvel, F.; Danner, S. M.; Ludolph, A. C.; Grycz, K.; Baczyk, M.; Zytnicki, D.; Roselli, F.

10.1101/2024.03.25.586570 — neuroscience — Posted on 2024-03-29

447 Converging inputs compete at the lateral parabrachial nuclei to dictate the affective-motivational responses to cold pain

Reddy, P.; Chaterji, S.; Varughese, A.; C, Y.; Sathyamurthy, A.; Barik, A.

10.1101/2024.03.25.586591 — neuroscience — Posted on 2024-03-29

448 Distinct Motor Map Characteristics for Biceps and Triceps Muscles in Persons with Chronic Tetraplegia: Implications for Arm Function

Liu, J.; Olaughlin, K.; Forrest, G. F.; Arora, T.; Nemunaitis, G.; Cunningham, D.; Kirshblum, S.; Pundik, S.; Baker, K.; Bryden, A.; Kilgore, K.; Bethoux, F.; Wang, X.; Henzel, M. K.; Brihmat, N.; Bayram, M. B.; Plow, E. B.

10.1101/2024.03.27.585546 — neuroscience — Posted on 2024-03-29

449 Functional-based parcellation of the mouse prefrontal cortex for network perturbation analysis

Savvateev, I.; Grimm, C.; Markicevic, M.; Grandjean, J.; Wenderoth, N.; Polania, R.; Zerbi, V.

10.1101/2024.03.25.586664 — neuroscience — Posted on 2024-03-29

450 Astrocytes mediate two forms of spike timing-dependent depression at entorhinal cortex-hippocampal synapses

Coatl-Cuaya, H.; Martinez-Gallego, I.; Rodriguez-Moreno, A.

10.1101/2024.03.25.586546 — neuroscience — Posted on 2024-03-29

451 A split-GAL4 driver line resource for Drosophila CNS cell types

Meissner, G. W.; Vannan, A.; Jeter, J.; Atkins, M.; Bowers, S.; Close, K.; DePasquale, G. M.; Dorman, Z.; Forster, K.; Beringer, J. A.; Gibney, T. V.; Gulati, A.; Hausenfluck, J. H.; He, Y.; Henderson, K.; Johnson, L.; Johnston, R. M.; Ihrke, G.; Iyer, N.; Lazarus, R.; Lee, K.; Li, H.-H.; Liaw, H.-P.; Melton, B.; Miller, S.; Motaher, R.; Novak, A.; Ogundeyi, O.; Petruncio, A.; Price, J.; Protopapas, S.; Tae, S.; Tata, A.; Taylor, J.; Vorimo, R.; Yarbrough, B.; Zeng, K. X.; Zugates, C. T.; Dionne, H.; Angstadt, C.; Ashley, K.; Cavallaro, A.; Dang, T.; Gonzalez, G. A.; Hibbard, K. L.; Huang, C.;

10.1101/2024.01.09.574419 — neuroscience — Posted on 2024-03-29

452 A Neural Index Reflecting the Amount of Cognitive Resources Available during Memory Encoding: A Model-based Approach

Ma, S.; Popov, V.; Zhang, Q.

10.1101/2022.08.16.504058 — neuroscience — Posted on 2024-03-29

453 Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across 5 fly Parkinsonism models

Pech, U.; Janssens, J.; Schoovaerts, N.; Kuenen, S.; Makhzami, S.; Hulselmans, G.; Poovathingal, S.; Bademosi, A. T.; Swerts, J.; Vilain, S. P.; Aerts, S.; Verstreken, P.

10.1101/2023.03.11.532176 — neuroscience — Posted on 2024-03-29

454 Acute and sub-chronic toxicity of 6PPD-quinone to early-life stage lake trout (Salvelinus namaycush)

Roberts, C.; Lin, J.; Kohlman, E.; Jain, N.; Amekor, M.; Alcaraz, A. J.; Hogan, N.; Hecker, M.; Brinkmann, M.

10.1101/2024.03.26.586843 — physiology — Posted on 2024-03-29

455 Comparative CNS Pharmacology of the Brutons Tyrosine Kinase (BTK) Inhibitor Tolebrutinib Versus Other BTK Inhibitor Candidates for Treating Multiple Sclerosis.

TURNER, T. J.; Brun, P.; Gruber, R.; Ofengeim, D.

10.1101/2024.03.25.586667 — pharmacology and toxicology — Posted on 2024-03-29

456 Crude extract of Ruellia tuberosa L. flower induces intracellular ROS, promotes DNA damage and apoptosis in Triple Negative Breast Cancer Cells

Guha, S.; Talukdar, D.; Mandal, G. K.; Mukherjee, R.; Ghosh, S.; Naskar, R.; Saha, P.; Murmu, N.; Das, G.

10.1101/2024.03.26.586749 — cancer biology — Posted on 2024-03-29

457 COCONUT: An analysis of coiled-coil regions in proteins

Soni, N.; Madhusudhan, M. S.

10.1101/2024.03.25.586698 — bioinformatics — Posted on 2024-03-29

458 Reliable cross-ion mode chemical similarity prediction between MS2 spectra

de Jonge, N. F.; Joas, D.; Truong, L.-J.; van der Hooft, J. J. J.; Huber, F.

10.1101/2024.03.25.586580 — bioinformatics — Posted on 2024-03-29

459 Foldclass and Merizo-search: embedding-based deep learning tools for protein domain segmentation, fold recognition and comparison

Kandathil, S. M.; Lau, A. M. C.; Jones, D. T.

10.1101/2024.03.25.586696 — bioinformatics — Posted on 2024-03-29

460 hoodscanR: profiling single-cell neighborhoods in spatial transcriptomics data

Liu, N.; Martin, J.; Bhuva, D. D.; Chen, J.; Li, M.; Lee, S. C.; Kharbanda, M.; Cheng, J.; Mohamed, A.; Kulasinghe, A.; Chen, Y.; Tan, C. W.; Davis, M. J.

10.1101/2024.03.26.586902 — bioinformatics — Posted on 2024-03-29

461 Baselining the Buzz. Trastuzumab-HER2 Affinity, and Beyond!

Chinery, L.; Hummer, A. M.; Mehta, B. B.; Akbar, R.; Rawat, P.; Slabodkin, A.; Le Quy, K.; Lund-Johansen, F.; Greiff, V.; Jeliazkov, J. R.; Deane, C. M.

10.1101/2024.03.26.586756 — bioinformatics — Posted on 2024-03-29

462 Comprehensive prediction and analysis of human protein essentiality based on a pre-trained protein large language model

Kang, B.; Fan, R.; Cui, C.; Cui, Q.

10.1101/2024.03.26.586900 — bioinformatics — Posted on 2024-03-29

463 py_ped_sim - A flexible forward genetic simulator for complex family pedigree analysis

Guardado, M. A.; Perez, C.; Campana, S.; Chavez-Rojas, B.; Magana, J.; Jackson, S.; Samperio, E.; Syas, K.; Hernandez, S.; Hernandez, R.; Zavala, E.; Rohlfs, R.

10.1101/2024.03.25.586501 — bioinformatics — Posted on 2024-03-29

464 Optimizing ODE-derived Synthetic Data for Transfer Learning in Dynamical Biological Systems

Zabbarov, J.; Witzke, S.; Kleissl, M.; Iversen, P.; Renard, B. Y.; Baum, K.

10.1101/2024.03.25.586390 — bioinformatics — Posted on 2024-03-29

465 Strain-resolved de-novo metagenomic assembly of viral genomes and microbial 16S rRNAs

Jochheim, A.; Jochheim, F. E.; Kolodyazhnaya, A.; Morice, E.; Steinegger, M.; Soeding, J.

10.1101/2024.03.29.587318 — bioinformatics — Posted on 2024-03-29

466 Matrimeres are systemic nanoscale mediators of tissue integrity and function

Debnath, K.; Qayoom, I.; O'Donnell, S.; Ekiert, J.; Wang, C.; Sanborn, M. A.; Liu, C.; Rivera, A.; Cho, I. S.; Saichellappa, S.; Toth, P. T.; Mehta, D.; Rehman, J.; Du, X.; Gao, Y.; Shin, J.-W.

10.1101/2024.03.25.586585 — bioengineering — Posted on 2024-03-29

467 Hamstrings are stretched more and faster during accelerative running compared to speed-matched constant speed running

Gurchiek, R. D.; Teplin, Z.; Falisse, A.; Hicks, J. L.; Delp, S. L.

10.1101/2024.03.25.586659 — bioengineering — Posted on 2024-03-29

468 Unravelling the glycome in human intervertebral disc degeneration: Aberrant glycosylation modulates inflammation and metabolism.

Joyce, K.; Scheper, A. F.; Phyo, A. M.; O'Flaherty, R.; Drake, R.; Devitt, A.; Marchetti-Deschmann, M.; Saldova, R.; Pandit, A.

10.1101/2024.03.26.585840 — bioengineering — Posted on 2024-03-29

469 RNA folding kinetics control riboswitch sensitivity in vivo

Bushhouse, D. Z.; Fu, J.; Lucks, J. B.

10.1101/2024.03.29.587317 — biochemistry — Posted on 2024-03-29

470 Comparative framework and adaptation of ACME HS approach to single cell isolation from fresh-frozen endocrine tissues

Utkina, M.; Shcherbakova, A.; Deviatiiarov, R.; Ryabova, A.; Marina Loguinova, M.; Trofimov, V.; Kuznetsova, A.; Petropavlovskiy, M.; Salimkhanov, R.; Maksimov, D.; Albert, E.; Golubeva, A.; Asaad, W.; Urusova, L.; Bondarenko, E.; Lapshina, A.; Shutova, A.; Beltsevich, D.; Gusev, O.; Dzeranova, L.; Melnichenko, G.; Minniakhmetov, I.; Dedov, I.; Mokrysheva, N.; Popov, S.

10.1101/2024.03.26.586727 — genomics — Posted on 2024-03-29

471 Genome-Wide Analysis of the Cucumber Kinome: Uncovering and Analyzing the Expression of Cucumis sativus Protein Kinases in Response to Biotic Stress

Costa, F. C. L.; Aono, A. H.; Silva, E. M. d. A.; Pereira, W. A.

10.1101/2023.03.16.532963 — genomics — Posted on 2024-03-29

472 Does Haldane's rule speciation within mimetic Poison frogs?

Lorioux-Chevalier, U.; Chouteau, M.; Roland, A.-B.

10.1101/2024.03.25.586569 — evolutionary biology — Posted on 2024-03-29

473 Taking fear back into the Marginal Value Theorem: the risk-MVT and optimal boldness

Calcagno, V.; Grognard, F.; Hamelin, F. M.; Mailleret, L.

10.1101/2023.10.31.564970 — evolutionary biology — Posted on 2024-03-29

474 Global invasion history and genomic signatures of adaptation of a highly invasive lace bug

Du, Z.; Wang, X.; Duan, Y.; Liu, S.; Tian, L.; Song, F.; Cai, W.; Li, H.

10.1101/2024.03.26.586866 — evolutionary biology — Posted on 2024-03-29

475 Biomass competition unifies individual and community scaling patterns

Fant, L.; Ghedini, G.

10.1101/2024.03.25.586593 — ecology — Posted on 2024-03-29

476 Challenges in quantifying functional redundancy and selection in microbial communities

Ho, P.-Y.; Huang, K.

10.1101/2024.03.26.586891 — ecology — Posted on 2024-03-29

477 Delayed localization of A-type lamins to the rupture sites in Hutchinson-Gilford progeria syndrome

Kono, Y.; Pack, C.-G.; Ichikawa, T.; Komatsubara, A.; Adam, S. A.; Miyazawa, K.; Rolas, L.; Nourshargh, S.; Medalia, O.; Goldman, R. D.; Fukuma, T.; Kimura, H.; Shimi, T.

10.1101/2023.09.02.555826 — cell biology — Posted on 2024-03-29

478 Inhibitory KIRs decrease HLA class II-mediated protection in Type 1 Diabetes

Mora-Bitria, L.; Debebe, B. J.; Miners, K.; Ladell, K.; Kaur, C.; Traherne, J. A.; Jiang, W.; Hadcocks, L.; McQuibban, N. A. R.; Trowsdale, J.; Wong, F. S.; Pontikos, N.; Niederalt, C.; Asquith, B.

10.1101/2024.03.27.586933 — immunology — Posted on 2024-03-29

479 Mitochondria-Associated Membranes Are Not Altered In Immune Cells In T2D

Hart, S. N.; Lenin, R.; Sturgill, J.; Kern, P. A.; Nikolajczyk, B. S.

10.1101/2024.03.25.586170 — immunology — Posted on 2024-03-29

480 Splicing-aware resolution of scRNA-Seq data

Lukyanov, D. K.; Egorov, E. S.; Kriukova, V. V.; Ladell, K.; Price, D.; Franke, A.; Chudakov, D. M.

10.1101/2024.03.25.586675 — immunology — Posted on 2024-03-29

481 Teaching deep networks to see shape: Lessons from a simplified visual world.

Jarvers, C.; Neumann, H.

10.1101/2024.03.25.586544 — neuroscience — Posted on 2024-03-29

482 Functional states of prelimbic and related circuits during the acquisition of a GO/noGO task in rats

Munoz-Redondo, C.; Parras, G. G.; Andreu-Sanchez, C.; Martin-Pascual, M. A.; DELGADO-GARCIA, J. M.; Gruart, A.

10.1101/2024.03.25.586558 — neuroscience — Posted on 2024-03-29

483 A role for δ subunit-containing GABA-A receptors on parvalbumin positive neurons in maintaining electrocortical signatures of sleep states

Lambert, P. M.; Salvatore, S. V.; Lu, X.; Shu, H.-J.; Benz, A.; Rensing, N.; Yuede, C.; Wong, M.; Zorumski, C. F.; Mennerick, S.

10.1101/2024.03.25.586604 — neuroscience — Posted on 2024-03-29

484 How short peptides can disassemble ultra-stable tau fibrils extracted from Alzheimers disease brain by a strain-relief mechanism

Hou, K.; Ge, P.; Sawaya, M. R.; Dolinsky, J. L.; Yang, Y.; Jiang, Y. X.; Lutter, L.; Boyer, D. R.; Cheng, X.; Pi, J.; Zhang, J.; Lu, J.; Yang, S.; Yu, Z.; Feigon, J.; Eisenberg, D. S.

10.1101/2024.03.25.586668 — neuroscience — Posted on 2024-03-29

485 Goal-directed vocal planning in a songbird

Zai, A. T.; Stepien, A. E.; Giret, N.; Hahnloser, R. H. R.

10.1101/2022.09.27.509747 — neuroscience — Posted on 2024-03-29

486 Modulation of Temporoammonic-CA1 Synapses by Neuropeptide Y is Through Y1 Receptors

Cortes, M. A.; Bartley, A. F.; Li, Q.; Davis, T. R.; Cunningham, S. E.; Perez, P. J.; Dobrunz, L. E.

10.1101/2024.03.26.586875 — neuroscience — Posted on 2024-03-29

487 Challenges and Efficacy of Astrocyte-to-Neuron Reprogramming in Spinal Cord Injury: In Vitro Insights and In Vivo Outcomes

NICEFORO, A.; Zholudeva, L. V.; Fernandes, S.; Lane, M. A.; Qiang, L.

10.1101/2024.03.25.586619 — neuroscience — Posted on 2024-03-29

488 Essential Dynamics of CB1 Receptor-Agonist Complexes: Implications for Signalling Bias

Fellner, D. M. J.; Glass, M.; Furkert, D. P.

10.1101/2024.03.25.586709 — neuroscience — Posted on 2024-03-29

489 KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3

Liu, Y.; Fan, M.; Yang, J.; Mihaljevic, L.; Chen, K. H.; Ye, Y.; Sun, S.; Qiu, Z.

10.1101/2024.03.26.586861 — neuroscience — Posted on 2024-03-29

490 Expert Navigators Deploy Rational Hierarchical Priorization Over Predictive Maps For Large-Scale Real-World Planning

Fernandez Velasco, P.; Griesbauer, E.-M.; Brunec, I.; Morley, J.; Manley, E.; McNamee, D.; Spiers, H.

10.1101/2024.03.25.586612 — neuroscience — Posted on 2024-03-29

491 Ultrasound pulse repetition frequency preferentially activates different neuron populations independent of cell type

Sherman, J.; Bortz, E.; San Antonio, E.; Tseng, H.-a.; Raiff, L.; Han, X.

10.1101/2024.03.25.586645 — neuroscience — Posted on 2024-03-29

492 HCN channels regulate excitability and gate synaptic amplification via NMDA in mouse L2/3 pyramidal neurons

Olah, V. J.; Wu, J.; Kaczmarek, L. K.; Rowan, M. J.

10.1101/2023.09.25.559198 — neuroscience — Posted on 2024-03-29

493 Metatranscriptomics-based metabolic modeling of patient-specific urinary microbiome during infection

Josephs-Spaulding, J.; Rettig, H. C.; Zimmermann, J.; Chkonia, M.; Mischnik, A.; Franzenburg, S.; Graspeuntner, S.; Rupp, J.; Kaleta, C.

10.1101/2024.03.25.586446 — systems biology — Posted on 2024-03-29

494 Guava cv. Allahabad Safeda Chromosome scale assembly and comparative genomics decodes breeder choice marker trait association for pink pulp colour

Mittal, A.; Thakur, S.; Sharma, A.; Boora, R. S.; Arora, N. K.; Singh, D.; Gill, M. S.; Dhillon, G. S.; Chhuneja, P.; Yadav, I.; Jindal, M.; Mathew, O. K.; Lachagari, V. B. R.; Paterson, A. H.

10.1101/2024.03.29.587319 — plant biology — Posted on 2024-03-29

495 Seamless, rapid and accurate analyses of outbreak genomic data using Split K-mer Analysis (SKA)

Derelle, R.; von Wachsmann, J.; Maeklin, T.; Hellewell, J.; Russell, T.; Lalvani, A.; Chindelevitch, L.; Croucher, N. J.; Harris, S. R.; Lees, J. A.

10.1101/2024.03.25.586631 — bioinformatics — Posted on 2024-03-29

496 Proposing a Systematic Lineage Classification Below the Genotype Level for Dengue Serotypes 1 and 2

Pereira, J. S.; Ribeiro, G.; de Souza, V. C.; Brcko, I. C.; Ribeiro, I. S.; De Lima, I. T. T.; Slavov, S. N.; Vessoni, S. C. S.; Sabbaga, M. C.; Lima, A. R. J.

10.1101/2024.03.25.586629 — bioinformatics — Posted on 2024-03-29

497 Regenerative human liver organoids (HLOs) in a pillar/perfusion plate for hepatotoxicity assays

Shrestha, S.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lekkala, V. K. R.; Liu, J.; Yang, Y.; Joshi, P.; Lee, M.-Y.

10.1101/2024.03.25.586638 — bioengineering — Posted on 2024-03-29

498 A NOVEL APPROACH TO RECOVERING OFF-TRACK ALIGNER TREATMENT THROUGH HYPER-ELASTIC POLYMER INNOVATION

PHAN, L. X.; MORA, C.; KLUCINSKA, A.

10.1101/2024.03.25.586642 — bioengineering — Posted on 2024-03-29

499 Spatial and temporal characteristics of laboratory-induced Anopheles coluzzii swarms: shape, structure and flight kinematics

Poda, B. S.; Cribellier, A.; Feugere, L.; Fatou, M.; Nignan, C.; Hien, D. F. d. S.; Müller, P.; Gnankine, O.; Dabire, R. K.; Diabate, A.; Muijres, F. T.; Roux, O.

10.1101/2024.03.25.586329 — animal behavior and cognition — Posted on 2024-03-29

500 Development of sound production in Danionella cerebrum

Groneberg, A. H.; Dressler, L. E.; Kadobianskyi, M.; Muller, J.; Judkewitz, B.

10.1101/2024.03.25.586601 — animal behavior and cognition — Posted on 2024-03-29

501 Computational Engineering of a Therapeutic Antibody to Inhibit Multiple Mutants of HER2 Without Compromising Inhibition of the Canonical HER2

Peled, S.; Guez-Haddad, J.; Zur Biton, N.; Nimrod, G.; Fischman, S.; Fastman, Y.; Ofran, Y.

10.1101/2023.07.21.550003 — bioinformatics — Posted on 2024-03-29

502 Transcriptomic, clonal, and functional analyses reveal Liver tissue-imprinted immuno-profile of circulating autoreactive CD4 T cells in autoimmune liver diseases

Cardon, A.; Guinebretiere, T.; Dong, C.; Gil, L.; Ado, S.; Gavlovsky, P.-j.; Braud, M.; Danger, R.; Schultheiss, C.; Domene, A.; Paul-Guilloteaux, P.; Chevalier, C.; Bernier, L.; Judor, J.-P.; Fourgeux, C.; Imbert, A.; Khaldi, M.; Bardou-Jacquet, E.; Elkrief, L.; Lannes, A.; Silvain, C.; Schnee, M.; Tanne, F.; Vavasseur, F.; Brusselle, L.; Brouard, S.; Kwok, W.; Mosnier, J.-F.; Lohse, A. W.; Poschmann, J.; Binder, M.; Gournay, J.; Conchon, S.; Milpied, P.; Renand, A.

10.1101/2024.03.26.586770 — immunology — Posted on 2024-03-29

503 Frequency-specific changes in prefrontal activity associated with maladaptive belief updating in volatile environments in euthymic bipolar disorder

Ivanova, M.; Germanova, K.; Dmitry, P.; Ragimova, A.; Kopytin, G.; Volel, B.; Nikulin, V.; Ruiz, M. H.

10.1101/2024.03.26.586656 — neuroscience — Posted on 2024-03-29

504 IT IS NOT A SMALL WORLD FOR PSYCHIATRIC PATIENTS

Akin, A.; Yorgancigil, E.; Ozturk, O. C.; Sutcubasi, B.; Kirimli, C. E.; Kirimli, E. E.; Dumlu, S. N.; Yukselen, G.; Erdogan, S. B.

10.1101/2024.03.25.586529 — neuroscience — Posted on 2024-03-29

505 Aging-associated long non-coding RNA boosts longevity and reduces the ribosome content of non-dividing fission yeast cells

Anver, S.; Sumit, A. F.; Sun, X.-M.; Hatimy, A.; Thalassinos, K.; Marguerat, S.; Alic, N.; Bahler, J.

10.1101/2024.03.25.586524 — genetics — Posted on 2024-03-29

506 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants

Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.

10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-29

507 LRH-1/NR5A2 Activation Rewires Immunometabolism Blunting Inflammatory Immune Cell Progression in Individuals with Type 1 Diabetes and Enhances Human Islet Function in Mice

Cobo-vuilleumier, N.; Rodriguez-Fernandez, S.; Lopez-Noriega, L.; Lorenzo, P. I.; Franco, J. M.; Lachaud, c. C.; Martin-Vazquez, E.; Araujo Legido, R.; Dorronsoro, A.; Lopez-Fernandez-Sobrino, R.; Fernandez-santos, b.; Salas-Lloret, D.; van Overbeek, N.; Ramos-Rodriguez, M.; Mateo-Rodriguez, C.; Hidalgo, L.; Nano, R.; Arroba, A. I.; Campos Caro, A.; Vertegaal, A. C.; Martin Montalvo, A.; Martin, F.; Aguilar-Diosdado, M.; Piemonti, L.; Pasquali, L.; Gonzalez Prieto, R.; Garcia Sanchez, M. I.; Martinez-Brocca, M.; Vives-Pi, M.; Gauthier, B. R.

10.1101/2023.09.18.558230 — cell biology — Posted on 2024-03-29

508 Characterization of West Nile virus Koutango lineage from Phlebotomine Sandflies in Kenya 2021

Thiiru, J. W.; Langat, S.; Mulwa, F.; Cinkovich, S.; Koka, H.; Yalwala, S.; Khamadi, S.; Onguso, J.; Odemba, N.; Ngere, F.; Johnson, J.; Egbo, T.; Garges, E.; Ojwang, E.; Eyase, F.

10.1101/2024.03.27.587075 — microbiology — Posted on 2024-03-29

509 Endosomal sorting protein SNX4 limits synaptic vesicle docking and release

Poppinga, J.; Barret, N. J.; Cornelisse, L. N.; Verhage, M.; van Weering, J. R. T.

10.1101/2024.03.15.584406 — neuroscience — Posted on 2024-03-29

510 Ketogenic Diet Induces Anti-Tumorigenic Effects in Colorectal Cancer through Microbial Production of Stearate

Tsenkova, M.; Brauer, M.; Kasakin, M.; Busi, S. B.; Schmoetten, M.; Gaigneaux, A.; Pozdeev, V.; Meyers, M.; Koncina, E.; Herebian, D.; Rodriguez, F.; Cheung, D.; Schmitz, M.; de Nies, L.; Mayatepek, E.; Haan, S.; de Beaufort, C.; Graas, J.; Cramer, T.; Linster, C.; Wilmes, P.; Letellier, E.

10.1101/2023.12.07.570549 — cancer biology — Posted on 2024-03-29

511 Assessing horizontal gene transfer in the rhizosphere of Brachypodium distachyon using fabricated ecosystems (EcoFABs)

Priya, S.; Rossbach, S.; Eng, T.; Andeer, P.; Lin, H.-H.; Mortimer, J.; Northen, T.; Mukhopadhyay, A.

10.1101/2024.03.14.584828 — microbiology — Posted on 2024-03-29

512 Siderophore-receptor coevolution analysis reveals habitat- and pathogen-specific bacterial iron interaction networks

Gu, S.; Shao, Z.; Qu, Z.; Zhu, S.; Shao, Y.; Zhang, D.; Allen, R.; He, R.; Shao, J.; Xiong, G.; Jousset, A.; Friman, V.-P.; Wei, Z.; Kuemmerli, R.; Li, Z.

10.1101/2023.11.05.565711 — microbiology — Posted on 2024-03-29

513 Differential increase of hippocampal subfield volume after socio-affective mental training relates to reductions in diurnal cortisol

Valk, S. L.; Engert, V.; Puhlmann, L.; Linz, R.; Caldairou, B.; Bernasconi, A.; Bernasconi, N.; Bernhardt, B. C.; Singer, T.

10.1101/2023.03.03.531039 — neuroscience — Posted on 2024-03-29

514 Role of Y box-binding protein 1 (Ybx1/ybx1) in zebrafish folliculogenesis: Promoting follicle cell proliferation via suppression of cell cycle inhibitor p21 (cdkn1a)

Zhu, B.; Zhang, Z.; Pardeshi, L.; Chen, Y.; Ge, W.

10.1101/2024.03.27.587099 — developmental biology — Posted on 2024-03-29

515 Independent size regulation of bones and appendages in zebrafish

Aramaki, T.; Kondo, S.

10.1101/2024.03.27.587111 — developmental biology — Posted on 2024-03-29

516 Spns1-dependent endocardial lysosomal function drives valve morphogenesis through Notch1-signaling.

Chavez, M. N.; Arora, P.; Ernst, A.; Meer, M.; Morales, R. A.; Mercader, N.

10.1101/2024.03.26.586825 — developmental biology — Posted on 2024-03-29

517 Capture of Human Neuromesodermal and Posterior Neural Tube Axial Stem Cells

Kelle, D.; Ugur, E.; Rusha, E.; Shaposhnikov, D.; Livigni, A.; Horschitz, S.; Davoudi, M.; Blutke, A.; Bushe, J.; Sterr, M.; Arkhipova, K.; Tak, B.; de Vries, R.; Hochane, M.; Spruijt, B.; Haji Ali, A.; Lickert, H.; Feuchtinger, A.; Koch, P.; Mann, M.; Leonhardt, H.; Wilson, V.; Drukker, M.

10.1101/2024.03.26.586760 — developmental biology — Posted on 2024-03-29

518 The transcription factor Tcf21 is required for specifying Foxd1 cells to the juxtaglomerular cell lineage

Anjum, H.; Yacu, G. S.; Medrano, S.; Gomez, R. A.; Sequeira-Lopez, M. L. S.; Quaggin, S. E.; Finer, G.

10.1101/2024.03.25.586641 — developmental biology — Posted on 2024-03-29

519 Stable germline transgenesis using the Minos Tc1/mariner element in the sea urchin, Lytechinus pictus.

Jackson, E. W.; Romero, E.; Lee, Y.; Kling, S.; Tjeerdema, E.; Hamdoun, A.

10.1101/2024.03.26.586777 — developmental biology — Posted on 2024-03-29

520 The homeobox transcription factor Cux1 coordinates postnatal epithelial developmental timing but is dispensable for lung organogenesis and regeneration

Zhao, B.; Socha, J.; Fernandes, S.; Warheit-Niemi, H.; Ruff, B.; Hershey, G. K. K.; VanDussen, K. L.; Swarr, D. T.; Zacharias, W. J.

10.1101/2024.03.26.586673 — developmental biology — Posted on 2024-03-29

521 Conserved DNA Methylation Signatures in The Prefrontal Cortex of Newborn and Juvenile Guinea Pigs Following Antenatal Corticosteroid Exposure

Kim, B.; Kostaki, A.; Matthews, S. G.

10.1101/2024.03.26.586671 — developmental biology — Posted on 2024-03-29

522 Distinct Gene Regulatory Dynamics Drive Skeletogenic Cell Fate Convergence During Vertebrate Embryogenesis

Wang, M.; Di Pietro-Torres, A.; Feregrino, C.; Luxey, M.; Moreau, C.; Fischer, S.; Fages, A.; Tschopp, P.

10.1101/2024.03.26.586769 — developmental biology — Posted on 2024-03-29

523 Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast

Melero, A.; Muriel-Lopez, O.; Basante-Bedoya, M.; Martin, S. G.

10.1101/2024.03.28.587130 — cell biology — Posted on 2024-03-29

524 Endothelial calcium firing mediates extravasation of metastatic tumor cells.

Peralta, M.; Dupas, A.; Larnicol, A.; Lefebvre, O.; Goswami, R.; Girardo, S.; Osmani, N.; Goetz, J. G.

10.1101/2024.03.28.587188 — cell biology — Posted on 2024-03-29

525 A modular and flexible open source cell incubator system for mobile and stationary use

Duru, J.; Maurer, B.; Ruff, T.; Hengsteler, J.; Girardin, S.; Voros, J.; Ihle, S. J.

10.1101/2024.03.27.587077 — cell biology — Posted on 2024-03-29

526 An evolutionary cell biology perspective into the diverging mechanisms of clathrin-mediated endocytosis in dikarya fungi

Picco, A.; Toret, C. P.; Rivier-Cordey, A.-S.; Kaksonen, M.

10.1101/2024.03.28.587219 — cell biology — Posted on 2024-03-29

527 A new cellular platform for studying autophagy

Goldin-Azulay, K.; Fraiberg, M.; Trofimyuk, O.; Reuven, N.; Levin, Y.; Kopitman, E.; Elazar, Z.

10.1101/2024.03.28.587157 — cell biology — Posted on 2024-03-29

528 SMARCA2 and SMARCA4 participate in DNA damage repair

Wu, D.; Yu, L.

10.1101/2024.03.28.587286 — cell biology — Posted on 2024-03-29

529 Using absorbance detection for hs-SV-AUC characterization of adeno-association virus

Larson, N. R.; Bou-Assaf, G. M.; Laue, T. M.; Berkowitz, S. A.

10.1101/2024.03.27.587092 — biophysics — Posted on 2024-03-29

530 Intrinsically disordered region amplifies membrane remodeling to augment selective ER-phagy

Poveda-Cuevas, S. A.; Lohachova, K.; Dikic, I.; Hummer, G.; Bhaskara, R. M.

10.1101/2024.03.28.587138 — biophysics — Posted on 2024-03-29

531 Nuclear blebs are associated with destabilized chromatin packing domains

Pujadas Liwag, E. M.; Acosta, N.; Almassalha, L. M.; Su, Y.; Gong, R.; Kanemaki, M. T.; Stephens, A. D.; Backman, V.

10.1101/2024.03.28.587095 — bioengineering — Posted on 2024-03-29

532 Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation

Niedner-Boblenz, A.; Monecke, T.; Hennig, J.; Klostermann, M.; Hofweber, M.; Davydova, E.; Gerber, A. P.; Anosova, I.; Mayer, W.; Mueller, M.; Heym, R.; Janowski, R.; Paillart, J.-C.; Dormann, D.; Zarnack, K.; Sattler, M.; Niessing, D.

10.1101/2024.03.27.586925 — biochemistry — Posted on 2024-03-29

533 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species

Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.

10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-29

534 Effect of translation enhancing nascent SKIK peptide on the arrest peptides containing consecutive Proline

Nishikawa, Y.; Fujikawa, R.; Nakano, H.; Kanamori, T.; Ojima-Kato, T.

10.1101/2024.02.28.582505 — synthetic biology — Posted on 2024-03-29

535 A practical guide to time-resolved fluorescence microscopy and spectroscopy

Clark, B. S.; Silvernail, I.; Gordon, K.; Castaneda, J. F.; Morgan, A. N.; Rolband, L. A.; LeBlanc, S. J.

10.1101/2024.01.25.577300 — biophysics — Posted on 2024-03-29

536 Analog epigenetic cell memory by graded DNA methylation

Palacios, S.; Bruno, S.; Weiss, R.; Salibi, E.; Kane, A.; Ilia, K.; Del Vecchio, D.

10.1101/2024.02.13.580200 — bioengineering — Posted on 2024-03-29

537 Heterogeneous responsiveness to environmental stimuli

Cavailles, J.; Grube, M.; Kuzmics, C.

10.1101/2023.01.26.525694 — animal behavior and cognition — Posted on 2024-03-29

538 Can recent evolutionary history promote resilience to environmental change?

Bladon, E. K.; Pascoal, S.; Kilner, R. M.

10.1101/2022.11.04.515151 — evolutionary biology — Posted on 2024-03-29

539 Spring haul-out behavior of seals in the Bering and Chukchi seas

London, J. M.; Conn, P. B.; Koslovsky, S. M.; Richmond, E. L.; Ver Hoef, J. M.; Cameron, M. F.; Crawford, J. A.; Von Duyke, A. L.; Quakenbush, L.; Boveng, P. L.

10.1101/2022.04.07.487572 — ecology — Posted on 2024-03-29

540 Bayesian Optimization of Neurostimulation (BOONStim)

Oliver, L. D.; Jeyachandra, J.; Dickie, E. W.; Hawco, C.; Mansour, S.; Hare, S. M.; Buchanan, R. W.; Malhotra, A. K.; Blumberger, D. M.; Deng, Z.-D.; Voineskos, A. N.

10.1101/2024.03.08.584169 — neuroscience — Posted on 2024-03-29

541 Topographical polarity reveals continuous EEG microstate transitions and electric field direction in healthy aging

Kashihara, S.; Asai, T.; Imamizu, H.

10.1101/2024.03.24.586427 — neuroscience — Posted on 2024-03-29

542 Visual homogeneity computations in the brain enable solving generic visual tasks

Jacob, G.; Pramod, R.; Arun, S.

10.1101/2022.12.03.518965 — neuroscience — Posted on 2024-03-29

543 Pure Nano Genesis: Pioneering Universal Aqueous Nanostrategies from Pure Molecules to Revolutionise Diverse Applications

Zhao, W.; Li, Q.; He, P.; Li, C.; Aryal, M.; Fabiilli, M.; Xiao, H.

10.1101/2024.03.24.586367 — pharmacology and toxicology — Posted on 2024-03-29

544 Tumor-infiltrating nerves functionally alter brain circuits and modulate behavior in a male mouse model of head-and-neck cancer

Barr, J.; Walz, A.; Restaino, A. C.; Amit, M.; Barclay, S. M.; Vichaya, E. G.; Spanos, W. C.; Dantzer, R.; Talbot, S.; Vermeer, P. D.

10.1101/2023.10.18.562990 — cancer biology — Posted on 2024-03-28

545 Microphase Separation Produces Interfacial Environment within Diblock Biomolecular Condensates

Latham, A. P.; Zhu, L.; Sharon, D. A.; Ye, S.; Willard, A. P.; Zhang, X.; Zhang, B.

10.1101/2023.03.30.534967 — biophysics — Posted on 2024-03-29

546 Biolearn, an open-source library for biomarkers of aging

Ying, K.; Paulson, S.; Eames, A.; Li, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Gobel, D.; Snyder, M.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.

10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-28

547 Wearable Disposable Electrotherapy

FallahRad, M.; Chaudhry, Z.; Belali Koochesfahani, M.; Bhuiyan, R.; Zaman, M.; Liu, T.; Saha, K.; Diaz Uraga, M. R.; Thahsin, M.; Couzis, A.; Bikson, M.

10.1101/2023.11.28.569062 — bioengineering — Posted on 2024-03-29

548 Diverse Database and Machine Learning Model to narrow the generalization gap in RNA structure prediction

de Lajarte, A.; Martin Des Taillades, Y.; Kalicki, C.; Fuchs, F.; Aruda, J.; Salazar, D.; Allan, M.; LEsperance-Kerckhoff, C.; Kashi, A.; Jossinet, F.; Rouskn, S.

10.1101/2024.01.24.577093 — biochemistry — Posted on 2024-03-29

549 MolEvolvR: A web-app for characterizing proteins using molecular evolution and phylogeny

Krol, J. D.; Burke, J. T.; Chen, S. Z.; Sosinski, L. M.; Alquaddoomi, F. S.; Brenner, E. P.; Wolfe, E. P.; Rubinetti, V. P.; Amolitos, S.; Reason, K. M.; Johnston, J. B.; Ravi, J.

10.1101/2022.02.18.461833 — genomics — Posted on 2024-03-29

550 Genome-wide analysis of transcription-coupled repair reveals novel transcription events in Caenorhabditis elegans

Kose, C.; Lindsey-Boltz, L.; Sancar, A.; Jiang, Y.

10.1101/2023.10.12.562083 — genomics — Posted on 2024-03-29

551 Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation

Klokman, G.; Xu, Y.; Bond, K.; Wu, X.; Schustak, J.; Mandelbaum, J.; Twarog, M.; Han, H.; Paulina, M.-K.; Coble, M.; Hayden, C.; Galarneau, J.-R.; Demirs, J.; Qiu, Y.; Esterberg, R.; Huang, Q.; Prasanna, G.; Saint-Geniez, M.; Aranda, J.; Bao, Y.

10.1101/2024.03.11.584455 — cell biology — Posted on 2024-03-28

552 Neutrophils actively swell to potentiate rapid migration

Nagy, T. L.; Strickland, E.; Weiner, O. D.

10.1101/2023.05.15.540704 — cell biology — Posted on 2024-03-29

553 Multiscale chromatin dynamics and high entropy in plant iPSC ancestors

Rutowicz, K.; Luethi, J.; de Groot, R.; Holtackers, R.; Yakimovich, Y.; Pazmino, D. M.; Gandrillon, O.; Pelkmans, L.; Baroux, C.

10.1101/2023.09.28.559735 — molecular biology — Posted on 2024-03-28

554 Prediction of antibiotic resistance at the patient level using deep learning

Inda-Diaz, J. S.; Johnning, A.; Hessel, M.; Sjoberg, A.; Lokrantz, A.; Helldal, L.; Jirstrand, M.; Svensson, L.; Kristiansson, E.

10.1101/2023.05.09.539832 — microbiology — Posted on 2024-03-28

555 In vitro antimicrobial activity of non-aureus Staphylococci and Mammaliicocci against Staphylococcus aureus and Streptococcus uberis and their relationship with the presence of intramammary infections in organic dairy cows

Pena-Mosca, F.; Gaire, T. N.; Dean, C. J.; Manriquez, D.; Pinedo, P.; Noyes, N.; Caixeta, L. S.

10.1101/2024.02.01.578391 — microbiology — Posted on 2024-03-29

556 Roles for RERE in lymphatic endothelial cell proliferation and survival, and human cystic lymphatic malformations

Rogerson, D. M.; Muley, A.; Vogel, Z.; Giordano, J.; Wapner, R.; Shawber, C.

10.1101/2024.03.24.586490 — cell biology — Posted on 2024-03-28

557 Simple shell measurements do not consistently predict habitat in turtles: a reply to Lichtig and Lucas (2017)

Evers, S. W.; Foth, C.; Joyce, W. G.; Hermanson, G.

10.1101/2024.03.25.586561 — paleontology — Posted on 2024-03-28

558 Mapping Motor Preparation in the Developing Brain: Insights from Contingent Negative Variation and Event-related Mu Rhythm Modulation

Schmidgen, J.; Heinen, T.; Konrad, K.; Bender, S.

10.1101/2024.03.25.586538 — developmental biology — Posted on 2024-03-28

559 The Genetic Puzzle of Multicopy Genes: Challenges and Troubleshooting

Partida, V. G. S.; Dias, H. M.; Portes, M. T.; Van Sluys, M.-A.

10.1101/2024.03.25.586576 — molecular biology — Posted on 2024-03-28

560 In situ structure and rotary states of mitochondrial ATP synthase in whole cells

Dietrich, L.; Agip, A.-N. A.; Schwarz, A.; Kunz, C.; Kühlbrandt, W.

10.1101/2024.03.27.586927 — molecular biology — Posted on 2024-03-28

561 Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressants

Arassi, M. B.; Karcher, N.; Mastrorilli, E.; Gross, M.; Brauer-Nikonow, A.; Hackett, R.; Czock, D.; Toenshoff, B.; Zeller, G.; Zimmermann, M.

10.1101/2024.03.28.586928 — microbiology — Posted on 2024-03-28

562 Characterization of sediment and granite hosted deep underground research laboratories reveals diverse microbiome functions, limited temporal variation and substantial genomic conservation

Amamo, Y.; Sachdeva, R.; Gittins, D.; Anantharaman, K.; Lei, S.; Valentin Alvarado, L. E.; Diamond, S.; Beppu, H.; Iwatsuki, T.; Mochizuki, A.; Miyakawa, K.; Ishii, E.; Murakami, H.; Jaffe, A. L.; Castelle, C.; Lavy, A.; Suzuki, Y.; Banfield, J. F.

10.1101/2024.03.28.587102 — microbiology — Posted on 2024-03-28

563 PIM kinase control of CD8 T cell protein synthesis and cell trafficking

Marchingo, J. M.; Spinelli, L.; Pathak, S.; Cantrell, D. A.

10.1101/2024.03.25.586560 — immunology — Posted on 2024-03-28

564 Lapidary: Identifying and reporting amino acid sequences in metagenomes using sequence reads and Diamond

Bloomfield, S. J.; Zomer, A. L.; Mather, A. E.

10.1101/2024.03.25.586564 — bioinformatics — Posted on 2024-03-28

565 Genetic interaction library screening with a next-generation dual guide CRISPR system

Burgold, T.; Karakoc, E.; Goncalves, E.; Dwane, L.; Barrio-Hernandez, I.; Silva, R. O.; Souster, E.; Sharma, M.; Beck, A.; Koh, G.; Zalmas, L.-P.; Garnett, M.; Bassett, A. R.

10.1101/2024.03.28.587052 — molecular biology — Posted on 2024-03-28

566 The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma

Chen, Y.-J. C.; Bhaskara, G. B.; Lu, Y.; Lin, K.; Dent, S. Y. R.

10.1101/2024.03.26.586811 — molecular biology — Posted on 2024-03-28

567 Caught in a trap: DNA contamination in tsetse xenomonitoring can lead to over-estimates of Trypanosoma brucei infection

Saldanha, I.; Lea, R.; Manangwa, O.; Garrod, G.; Haines, L. R.; Acosta-Serrano, A.; Auty, H.; Betson, M.; Lord, J. S.; Morrison, L. J.; Mramba, F.; Torr, S. J.; Cunningham, L. J.

10.1101/2024.03.25.586549 — molecular biology — Posted on 2024-03-28

568 Ribosomal composition affects the noncanonical translation and toxicity of polyglycine-containing proteins in fragile X-associated conditions

Tutak, K.; Broniarek, I.; Zielezinski, A.; Niewiadomska, D.; Baud, A.; Sobczak, K.

10.1101/2024.03.27.586952 — molecular biology — Posted on 2024-03-28

569 Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis

Rodriguez, L. R.; Alysandratos, K.-D.; Katzen, J.; Murthy, A.; Barboza, W. R.; Tomer, Y.; Acin-Perez, R.; Petcherski, A.; Minakin, K.; Carson, P.; Iyer, S.; Chavez, K.; Cooper, C. H.; Babu, A.; Weiner, A. I.; Vaughan, A. E.; Arany, Z.; Shirihai, O. S.; Kotton, D. N.; Beers, M. F.

10.1101/2024.03.26.586649 — molecular biology — Posted on 2024-03-28

570 High resolution maps of chromatin reorganization through mouse meiosis reveal novel features of the 3D meiotic structure

Cheng, G.; Pratto, F.; Brick, K.; Li, X.; Alleva, B.; Huang, M.; Lam, G.; Camerini-Otero, R. D.

10.1101/2024.03.25.586627 — molecular biology — Posted on 2024-03-28

571 Building a Collaborative DNA Barcode Library for the Diptera of Churchill, Canada: A Resource for Northern Research

Majoros, S. E.; Wang, J.; Levesque-Beaudin, V.; Borkent, C. J.; Brodo, F.; Brooks, S. E.; Boucher, S.; Cumming, J. M.; Currie, D. C.; Ekrem, T.; Elliott, T. A.; Hebert, P. D. N.; Savage, J.; Schaefer, P.; Sinclair, B. J.; Skevington, J. H.; Solecki, A. M.; Stur, E.; Wheeler, T. A.; Woodcock, T. S.; Young, A. D.; Young, C.; Adamowicz, S. J.

10.1101/2024.03.27.586819 — molecular biology — Posted on 2024-03-28

572 Plant Cleavage Factor I complex is essential for precise cleavage and polyadenylation site determination

Szewc, L.; Zhang, X.; Bajczyk, M.; Bielewicz, D.; Zimna, M.; Yura, K.; Mariko Kato, M.; Nomoto, M.; Garcia-Leon, M.; Rubio, V.; Tada, Y.; Furumoto, T.; Aoyama, T.; Szweykowska-Kulinska, Z.; Staiger, D.; Jarmolowski, A.; Tsuge, T.

10.1101/2024.03.28.587165 — molecular biology — Posted on 2024-03-28

573 Modulation of Vibrio cholerae gene expression through conjugative delivery of engineered regulatory small RNAs

Menendez-Gil, P.; Veleva, D.; Ramalhete, R.; Ho, B. T.

10.1101/2024.03.28.587233 — microbiology — Posted on 2024-03-28

574 The Role of Morphological Adaptability in Vibrio cholerae's Motility and Pathogenicity

Xu, J.; Abe, K.; Kodama, T.; Sultana, M.; Chac, D.; Markiewicz, S. M.; Kuba, E.; Tsunoda, S.; Alam, M.; Weil, A. A.; Nakamura, S.; Yamashiro, T.

10.1101/2024.03.27.586043 — microbiology — Posted on 2024-03-28

575 Characterization of West Nile virus Koutango lineage from Phlebotomine Sandflies in Kenya 2021

Thiiru, J. W.; Langat, S.; Mulwa, F.; Cinkovich, S.; Koka, H.; Yalwala, S.; Khamadi, S.; Onguso, J.; Odemba, N.; Ngere, F.; Johnson, J.; Egbo, T.; Garges, E.; Ojwang, E.; Eyase, F.

10.1101/2024.03.27.587075 — microbiology — Posted on 2024-03-28

576 IFNgamma-dependent remodelling of the myeloid landscape underlies control of IFNgamma-insensitive tumours

Lau, V. W. C.; Mead, G.; Mazet, J. M.; Krishnan, A.; Roberts, E. W.; Prota, G.; Gileadi, U.; Cerundolo, V.; Gerard, A.

10.1101/2024.03.25.586537 — immunology — Posted on 2024-03-28

577 Inflammation induced Th17 cells synergize with the inflammation-trained microbiota to mediate host-resiliency against intestinal injury

Golob, J. L.; Hou, G.; Swanson, B.; Bishu, S.; Grasberger, H.; El-Zaatari, M.; Lee, A.; Kao, J. Y.; Kamada, N.; Bishu, S.

10.1101/2024.03.25.586435 — immunology — Posted on 2024-03-28

578 Water position prediction with SE(3)-Graph Neural Network

Park, S.

10.1101/2024.03.25.586555 — bioinformatics — Posted on 2024-03-28

579 Identification of Aggregation Pheromone in Odontothrips loti (Thysanoptera: Thripidae)

Yanqi, L.; Ying ning, L.; Chang, L.; Liping, B.

10.1101/2024.03.25.586550 — ecology — Posted on 2024-03-28

580 Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping

Holm Bonnelykke, T.; Chabry, M.-A.; Perthame, E.; Desgrange, A.; Meilhac, S.

10.1101/2024.03.25.586543 — developmental biology — Posted on 2024-03-28

581 Single-Molecule Imaging Reveals the Mechanism of Bidirectional Replication Initiation in Metazoa

Terui, R.; Berger, S. E.; Sambel, L. A.; Song, D.; Chistol, G.

10.1101/2024.03.28.587265 — molecular biology — Posted on 2024-03-28

582 CRISPR-MIP replaces PCR and reveals GC and oversampling bias in pooled CRISPR screens

Selinger, M.; Yakovenko, I.; Nazir, I.; Henriksson, J.

10.1101/2024.03.28.587082 — molecular biology — Posted on 2024-03-28

583 Synthetic mycolates derivatives as molecular tools to decipher protein mycoloylation, a unique post-translational modification in bacteria.

Lesur, E.; Zhang, Y.; Dautin, N.; Dietrich, C.; Li de la Sierra-Gallay, I.; Augusto, L.; Rollando, P.; Lazar, N.; Urban, D.; Doisneau, G.; Constantinesco-Becker, F.; Van Tilbeurgh, H.; Guianvarc'h, D.; Bourdreux, Y.; Bayan, N.

10.1101/2024.03.28.587066 — microbiology — Posted on 2024-03-28

584 Conserved jumbo phage factors required for protein import into a phage nucleus

Kokontis, C.; Klein, T. A.; Silas, S.; Bondy-Denomy, J.

10.1101/2024.03.27.586873 — microbiology — Posted on 2024-03-28

585 Hepatitis E virus replication is facilitated by epithelial cell turnover and targets enteroendocrine cells in human intestinal organoids

Santos-Ferreira, N.; Zhang, X.; Van Dycke, J.; Neyts, J.; Kaptein, S.; Rocha-Pereira, J.

10.1101/2024.03.27.586953 — microbiology — Posted on 2024-03-28

586 Development of differential sublaminar feedforward inhibitory circuits in CA1 hippocampus requires Satb2

Hanson, M. A.; Bibi, N.; Safa, A.; Nagarajan, D.; Marshall, A. H.; Johantges, A. C.; Wester, J. C.

10.1101/2024.01.23.576902 — neuroscience — Posted on 2024-03-28

587 Mechanical cues of extracellular matrix determines tumor innervation

Jiang, S.-H.; Zhang, S.; Cai, Z.; Yu, M.-H.; Li, H.; Jiang, L.; Cai, S.; Zhu, Y.; Wang, H.; Huo, R.-X.; Xia, X.; Yao, H.-F.; Zhu, L.; Zhang, X.-L.; Hu, L.-P.; Li, Q.; Li, J.; Huo, Y.-M.; Hua, R.; Xue, J.; Jiang, C.; Sun, Y.-W.; Zhang, J.-F.; Zhang, Z.-Z.; Liu, D.-J.; Xiao, G. G.-S.; Zhang, Z.-G.

10.1101/2024.03.25.586535 — neuroscience — Posted on 2024-03-28

588 Multiplexed 3D Analysis of Immune States and Niches in Human Tissue

Yapp, C.; Nirmal, A. J.; Zhou, F. Y.; Maliga, Z.; Tefft, J.; Montero Llopis, P.; Murphy, G. F.; Lian, C.; Danuser, G.; Santagata, S.; Sorger, P. K.

10.1101/2023.11.10.566670 — cancer biology — Posted on 2024-03-28

589 Label-guided seed-chain-extend alignment on annotated De Bruijn graphs

Mustafa, H.; Karasikov, M.; Mansouri Ghiasi, N.; Rätsch, G.; Kahles, A.

10.1101/2022.11.04.514718 — bioinformatics — Posted on 2024-03-28

590 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping

Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Queiroga, V.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.

10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-28

591 High-throughput selection of glucose-binding proteins from massive datasets: Integrating molecular docking and molecular dynamics simulations

Makare, A.; Chaudhary, A.; De, D.; Deshpande, P.; Panwar, A. S.

10.1101/2024.03.20.585966 — bioinformatics — Posted on 2024-03-28

592 Structure and methyl-lysine binding selectivity of the HUSH complex subunit MPP8

Nikolopoulos, N.; Oda, S.-i.; Prigozhin, D. M.; Modis, Y.

10.1101/2023.12.21.572340 — biochemistry — Posted on 2024-03-28

593 The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger Adults

Harris, K. M.; Levitt, B. E.; Gaydosh, L.; Martin, C.; Meyer, J. M.; Mishra, A. A.; Kelly, A. L.; Aiello, A. E.

10.1101/2024.03.21.585983 — genomics — Posted on 2024-03-28

594 Sequence-based genome-wide association studies reveal the polygenic architecture of Varroa destructor resistance in Western honey bees Apis mellifera

Eynard, S. E.; Mondet, F.; Basso, B.; Bouchez, O. E.; Le Conte, Y.; Dainat, B.; Decourtye, A.; Genestout, L.; Guichard, M.; Guillaume, F.; Labarthe, E.; Locke, B.; Mahla, R.; de Miranda, J. R.; Neuditschko, M.; Phocas, F.; Tabet, K.; Vignal, A.; Servin, B.

10.1101/2024.02.16.580755 — genetics — Posted on 2024-03-28

595 Cell swelling enhances GPCR ternary complex formation, underpinning the potentiation of beta2 adrenergic receptor-mediated cAMP response

Sirbu, A.; Bathe-Peters, M.; Inoue, A.; Lohse, M.; Annibale, P.

10.1101/2023.06.23.544496 — cell biology — Posted on 2024-03-28

596 Bacterial pathogens dynamic during multi-species infections

Barny, M.-A.; Thieffry, S.; Gomes de Faria, C.; Thebault, E.; Pedron, J.

10.1101/2023.12.06.570389 — microbiology — Posted on 2024-03-28

597 Molecular epidemiology of Cercospora leaf spot on resistant and susceptible sugar beet hybrids

Chen, C.; Keunecke, H.; Neu, E.; Kopisch-Obuch, F. J.; McDonald, B. A.; Stapley, J.

10.1101/2023.10.30.564591 — pathology — Posted on 2024-03-28

598 Three-dimensional assessments are necessary to determine the true, spatially-resolved composition of tissues

Forjaz, A.; Vaz, E.; Romero, V. M.; Joshi, S.; Braxton, A. M.; Jiang, A. C.; Fujikura, K.; Cornish, T.; Hong, S.-M.; Hruban, R. H.; Wu, P.-H.; Wood, L. D.; Kiemen, A. L.; Wirtz, D.

10.1101/2023.12.04.569986 — cancer biology — Posted on 2024-03-28

599 Using splines for point spread function calibration atnon-uniform depths in localization microscopy

Korovin, S.; Kalisvaart, D.; Hung, S.-T.; Cnossen, J.; de Visser, C.; Smith, C. S.

10.1101/2024.01.24.577007 — biophysics — Posted on 2024-03-28

600 Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells

Valverde-Mendez, D.; Sunol, A. M.; Bratton, B. P.; Delarue, M.; Hofmann, J. L.; Sheehan, J. P.; Gitai, Z.; Holt, L. J.; Shaevitz, J. W.; Zia, R. N.

10.1101/2024.03.27.587083 — biophysics — Posted on 2024-03-28

601 Remotely controlled drug release in deep brain regionsof non-human primates

Wilson, M. G.; Webb, T. D.; Odeen, H.; Kubanek, J.

10.1101/2023.10.09.561539 — bioengineering — Posted on 2024-03-28

602 Evolution of olfactory sensitivity, preferences and behavioral responses in Mexican cavefish: fish personality matters

Blin, M.; Valay, L.; Kuratko, M.; Pavie, M.; Retaux, S.

10.1101/2023.10.02.560458 — animal behavior and cognition — Posted on 2024-03-28

603 Functional phases define the response of the soil microbiome to environmental change

Lee, K. K.; Liu, S.; Crocker, K.; Huggins, D. R.; Tikhonov, M.; Mani, M.; Kuehn, S.

10.1101/2024.03.15.584851 — ecology — Posted on 2024-03-28

604 Stage-specific expression patterns and co-targeting relationships among miRNAs in the developing mouse cerebral cortex

Todorov, H.; Weissbach, S.; Schlichtholz, L.; Mueller, H.; Hartwich, D.; Gerber, S.; Winter, J.

10.1101/2023.12.16.571081 — developmental biology — Posted on 2024-03-28

605 Liver regeneration by oval cells employing bistability of stemness-senescence, Hippo signaling, EMT-MET, and polyploidy circuit

Lazovska, M.; Salmina, K.; Pjanova, D.; Gerashchenko, B. I.; Erenpreisa, J.

10.1101/2024.03.26.586724 — cell biology — Posted on 2024-03-28

606 Lossless Single-Molecule Counting To Absolute QuantifyProteoforms

Gross, T.; Hundertmark, T.; Csiszar, V.; Sulyok, A. A.; Gross, N.; Breiden, M.; Kitschen, N.; von Groll, U.; Niemoller, C.; Sanchez-Martin, P.; Hein, A.; Gopffert, J.; Szoradi, T.; Luebbert, P.; Koltay, P.; Porschewski, P.; von Stetten, F.; Zengerle, R.; Jeney, C.

10.1101/2024.03.19.585761 — molecular biology — Posted on 2024-03-28

607 Delta-rhythmic activity in the medulla develops coincident with cortical delta in sleeping infant rats

Ahmad, M.; Kim, J.; Dwyer, B.; Sokoloff, G.; Blumberg, M. S.

10.1101/2023.12.16.572000 — neuroscience — Posted on 2024-03-28

608 Understanding Author Publishing Choices for Conservation Journals

Yoh, N.; Holle, M. J. M.; Willis, J.; Rudd, L. F.; Fraser, I. M.; Verissimo, D.

10.1101/2023.08.24.554591 — scientific communication and education — Posted on 2024-03-28

609 Does Music Training Improve Inhibition Control in Children? A Systematic Review and Meta-Analysis

Jamey, K.; Foster, N. E. V.; Hyde, K. L.; Dalla Bella, S.

10.1101/2023.02.08.527718 — scientific communication and education — Posted on 2024-03-28

610 Convergent evolution of desiccation tolerance in grasses

Marks, R. A.; Van Der Pas, L.; Schuster, J.; Gilman, I. S.; VanBuren, R.

10.1101/2023.11.29.569285 — plant biology — Posted on 2024-03-28

611 Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription

Cigrang, M.; Obid, j.; Davidson, i.; Nogaret, M.; ye, t.; davidson, g.; Catez, P.; Berico, P.; capelli, c.; Marechal, C.; Zachayus, A.; Elly, C.; Li, T.-K.; Compe, E.; Aviles, P.; egly, j.-m.; Cuevas, C.; Coin, F.

10.1101/2024.03.26.586754 — cancer biology — Posted on 2024-03-28

612 Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate

Borar, P.; Biswas, T.; Chaudhuri, A.; Huxford, T.; Chakrabarti, S.; Ghosh, G.; Polley, S.

10.1101/2023.06.27.546692 — biochemistry — Posted on 2024-03-28

613 A zebrafish system for identifying genetic dependencies in melanocytes and melanoma

Perlee, S.; Ma, Y.; Hunter, M. V.; Swanson, J. B.; Ming, Z.; Xia, J.; Lionnet, T.; McGrail, M.; White, R.

10.1101/2024.03.22.586101 — genetics — Posted on 2024-03-28

614 Latitudinal scaling of aggregation with abundance and its consequences for coexistence in species rich forests

Wiegand, T.; Wang, X.; Fischer, S.; Kraft, N. J. B.; Bourg, N. A.; Brockelman, W. Y.; Cao, M.; Chanthorn, W.; Chu, C.; Davies, S.; Ediriweera, S.; Gunatilleke, C. V. S.; Gunatilleke, I. A. U. N.; Hao, Z.; Howe, R.; Jiang, M.; Jin, G.; Kress, W. J.; Li, B.; Lian, J.; Lin, L.; Liu, F.; Ma, K.; McShea, W.; Mi, X.; Myers, J. A.; Nathalang, A.; Orwig, D. A.; Shen, G.; Su, S.-H.; Sun, I.-F.; Wang, X.; Wolf, A.; Yan, E.; Ye, W.; Zhu, Y.; Huth, A.

10.1101/2023.05.18.541254 — ecology — Posted on 2024-03-28

615 Differential warming at crown scale impacts walnut primary growth onset and secondary growth rate

Dusart, N.; Moulia, B.; Saudreau, M.; Serre, C.; Charrier, G.; Hartmann, F. P.

10.1101/2024.03.25.586536 — developmental biology — Posted on 2024-03-28

616 Altered X-chromosome inactivation predisposes to autoimmunity

Huret, C.; Ferraye, L.; David, A.; Mohamed, M.; Valentin, N.; Charlotte, F.; Savignac, M.; Goodhardt, M.; Guery, J.-C.; Rougeulle, C.; Morey, C.

10.1101/2023.04.20.537662 — immunology — Posted on 2024-03-28

617 Tracking how attentional focusing in working memory benefits long-term memory

Wang, S.; van Ede, F.

10.1101/2024.03.25.586271 — neuroscience — Posted on 2024-03-28

618 Variations of autonomic arousal mediate the reportability of mind-blanking occurrences

Boulakis, P. A.; Simos, N. J.; Zoi, S.; Mortaheb, S.; Schmidt, C.; Raimondo, F.; Demertzi, A.

10.1101/2024.03.26.586648 — neuroscience — Posted on 2024-03-28

619 Bidirectional modulation of reward-guided decision making by dopamine

Dias Maile, A. A.; Gründler, T. O. J.; Froböse, M. I.; Kurtenbach, H.; Kaiser, L. F.; Jocham, G.

10.1101/2024.03.27.586793 — neuroscience — Posted on 2024-03-28

620 Electroencephalographic Biomarkers of Relaxation: A Systematic Review and Meta-analysis

Sugimoto, K.; Kurashiki, H.; Xu, Y.; Takemi, M.; Amano, K.

10.1101/2024.03.27.586444 — neuroscience — Posted on 2024-03-28

621 Dynamics of compartment-specific proteomic landscapes of hepatotoxic and cholestatic models of liver fibrosis

Jirouskova, M.; Harant, K.; Cejnar, P.; Ojha, S.; Korelova, K.; Sarnova, L.; Sticova, E.; Mayr, C.; Schiller, H. B.; Gregor, M.

10.1101/2024.03.26.586230 — pathology — Posted on 2024-03-28

622 AutoXAI4Omics: an Automated Explainable AI tool for Omics and tabular data

Strudwick, J.; Gardiner, L.-J.; Denning-James, K.; Haiminen, N.; Evans, A.; Kelly, J.; Madgwick, M.; Utro, F.; Seabolt, E.; Gibson, C.; Bedi, B.; Clayton, D.; Howell, C.; PARIDA, L.; Carrieri, A. P.

10.1101/2024.03.25.586460 — bioinformatics — Posted on 2024-03-28

623 The art of seeing the elephant in the room: 2D embeddings of single-cell data do make sense

Lause, J.; Kobak, D.; Berens, P.

10.1101/2024.03.26.586728 — genomics — Posted on 2024-03-28

624 Linked emergence of racial disparities in mental health and epigenetic biological aging across childhood and adolescence

Aikins, M. A.; Willems, Y. E.; Mitchell, C.; Goosby, B.; Raffington, L.

10.1101/2024.03.26.586786 — genomics — Posted on 2024-03-28

625 Unravelling the architecture of Major Histocompatibility Complex class II haplotypes in rhesus macaques

de Groot, N.; van der Wiel, M.; Le, N. G.; de Groot, N. G.; Bruijnesteijn, J.; Bontrop, R. E.

10.1101/2024.03.26.586730 — genetics — Posted on 2024-03-28

626 Exaptation and de novo mutations transcend cryptic variations as drivers of adaptation in yeast

Routh, S.; Lindsay, R. J.; Gudelj, I.; Dhar, R.

10.1101/2024.03.26.586634 — evolutionary biology — Posted on 2024-03-28

627 Radioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis

Lauer, D.; Magnin, C. Y.; Kolly, L.; Wang, H.; Brunner, M.; Chabria, M.; Cereghetti, G. M.; Gabrys, H. S.; Tanadini-Lang, S.; Uldry, A.-C.; Heller, M.; Verleden, S.; Klein, K.; Sarbu, A.-C.; Funke-Chambour, M.; Ebner, L.; Distler, O.; Maurer, B.; Gote-Schniering, J.

10.1101/2024.03.27.586923 — molecular biology — Posted on 2024-03-28

628 Spermidine/spermine N1-acetyltransferase controls tissue-specific regulatory T cell function in chronic inflammation

Neuwirth, T.; Malzl, D.; Knapp, K.; Tsokkou, P.; Kleissl, L.; Redl, A.; Freystaetter, C.; Marella, N.; Kutschat, A. P.; Ponweiser, E.; Haschemi, A.; Seruggia, D.; Menche, J.; Wagner, E. F.; Stary, G.

10.1101/2024.03.25.586519 — immunology — Posted on 2024-03-28

629 Repetitive head impacts induce neuronal loss and neuroinflammation in young athletes

Butler, M. L. M. D.; Pervaiz, N.; Ypsilantis, P.; Wang, Y.; Breda, J. C.; Mazzilli, S. A.; Nicks, R.; Spurlock, E.; Hefti, M. M.; Huber, B. R.; Alvarez, V. E.; Stein, T. D.; Campbell, J. D.; McKee, A. C.; Cherry, J. D.

10.1101/2024.03.26.586815 — neuroscience — Posted on 2024-03-28

630 The respiratory cycle modulates distinct dynamics of affective and perceptual decision-making

Braendholt, M.; Nikolova, N.; Vejlo, M.; Banellis, L.; Fardo, F.; Allen, M.

10.1101/2024.03.26.586076 — neuroscience — Posted on 2024-03-28

631 A Systems Biology Analysis of Chronic Lymphocytic Leukemia

Pozzati, G.; Zhou, J.; Hazan, H.; Klement, G. L.; Siegelmann, H. T.; Rietman, E. A.; Tuszynski, J. A.

10.1101/2024.03.26.586690 — systems biology — Posted on 2024-03-28

632 Quantitative modelling of signaling in aggressive B cell lymphoma unveils conserved core network

Klinger, B.; Rausch, I.; Sieber, A.; Kutz, H.; Kruse, V.; Kirchner, M.; Mertins, P.; Kieser, A.; Bluthgen, N.; Kube, D.

10.1101/2024.03.25.586526 — systems biology — Posted on 2024-03-28

633 The iPhylo Suite: An Interactive Platform for Building and Annotating Biological and Chemical Taxonomic Trees

Li, Y.; Peng, C.; Chi, F.; Huang, Z.; Yuan, M.; Jiang, C.

10.1101/2024.03.25.586513 — bioinformatics — Posted on 2024-03-28

634 Spatial structure could explain the maintenance of alternative reproductive tactics in tree cricket males

Sadiq, M. A.; Bhat, A. S.; Guttal, V.; Balakrishnan, R.

10.1101/2024.03.25.586515 — animal behavior and cognition — Posted on 2024-03-28

635 Bettering of Learning Activity through Elevated P-Cresol Levels in the Brain: Insights from Active Avoidance Testing in Wistar Rats

Tevzadze, G.; Zhuravliova, H.; Kikvidze, Z.; Kiknadze, N.; Shetekauri, T.; Tkemaladze, N.

10.1101/2024.03.25.586517 — animal behavior and cognition — Posted on 2024-03-28

636 What We (Don't) Know about Parrot Welfare: A Systematic Literature Review

Piseddu, A.; van Zeeland, Y.; Rault, J.-L.

10.1101/2024.03.27.586789 — animal behavior and cognition — Posted on 2024-03-28

637 The Mycobacterium tuberculosis transposon sequencing database (MtbTnDB): a large-scale guide to genetic conditional essentiality

Jinich, A.; Zaveri, A.; DeJesus, M. A.; Flores-Bautista, E.; Almada-Monter, R.; Smith, C. M.; Sassetti, C. M.; Rock, J. M.; Ehrt, S.; Schnappinger, D.; Ioerger, T. R.; Rhee, K. Y.

10.1101/2021.03.05.434127 — microbiology — Posted on 2024-03-28

638 Neural substrates and behavioral relevance of speech envelope tracking: evidence from post-stroke aphasia

De Clercq, P.; Kries, J.; Vanthornhout, J.; Gerrits, R.; Francart, T.; Vandermosten, M.

10.1101/2024.03.26.586859 — neuroscience — Posted on 2024-03-28

639 Two separate but interconnected pattern formation systems are required to control body-axis and head-organiser formation in Hydra

Mercker, M.; Tursch, A.; Veerman, F.; Kazarnikov, A.; Höger, S.; Lengfeld, T.; Özbek, S.; Holstein, T. W.; Marciniak-Czochra, A.

10.1101/2021.02.05.429954 — developmental biology — Posted on 2024-03-28

640 Structural basis for recognition of the FLAG-tag by anti-FLAG M2

Beugelink, J. W.; Sweep, E.; Janssen, B. J. C.; Snijder, J.; Pronker, M. F.

10.1101/2024.03.25.586599 — biochemistry — Posted on 2024-03-28

641 Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomes

Salminen, T. S.; Vesala, L.; Basikhina, Y.; Kutzer, M.; Tuomela, T.; Lucas, R.; Monteith, K.; Prakash, A.; Tietz, T.; Vale, P. F.

10.1101/2024.03.28.587162 — immunology — Posted on 2024-03-28

642 Orthohantavirus Diversity in Central-East Argentina: Insights from Complete Genomic Sequencing on Phylogenetics, Geographic patterns and Transmission scenarios.

Alonso, D. O.; Kehl, S.; Coelho, R.; Periolo, N.; Poklepovich, T.; Perez-Sautu, U.; Sanchez-Lockhart, M.; Palacios, G. F.; Bellomo, C.; Martinez, V.

10.1101/2024.03.25.586579 — genomics — Posted on 2024-03-28

643 Genome-wide association study elucidates the genetic architecture of manganese tolerance in Brassica napus

Raman, H.; Bai, Z.; McVittie, B.; Mukherjee, S.; Goold, H.; Qiu, Y.; Zhang, Y.; Khin, N. C.; Liu, S.; Delourme, R.; Pogson, B. J.; Balasubramanian, S.; Raman, R.

10.1101/2024.03.27.586972 — plant biology — Posted on 2024-03-28

644 Optical Control of Cardiac Electrophysiology by thePhotochromic Ligand AB2

Fehrentz, T.; Kloecker, N.; Amin, E.

10.1101/2024.03.24.586505 — pharmacology and toxicology — Posted on 2024-03-28

645 Spatially resolved niche and tumor microenvironmental alterations in gastric cancer peritoneal metastases

Zhao, J. J.; Ong, J. C.-A.; Srivastava, S.; Chia, D. K. A.; Ma, H.; Huang, K. K.; Sheng, T.; Ramnarayanan, K.; Ong, X.; Tay, S. T.; Hagihara, T.; Tan, A. L. K.; Teo, M. C. C.; Tan, Q. X.; Ng, G. W. X.; Tan, J. W.-S.; Ng, M. C. H.; Gwee, Y. X.; Walsh, R.; Shabbir, A.; Kim, G.; Tay, Y. M. S.; Her, Z.; Leoncini, G.; Teh, B. T.; Hong, J. H.; Tay, R. Y. K.; Teo, C. B.; Dings, M. P. G.; Bijlsma, M.; Lum, J. H. Y.; Law, J. H.; Pietrantonio, F.; Blum, S. M.; Laarhoven, H. v.; Klempner, S.; Yong, W. P.; So, J. B. Y.; Chen, Q.; Tan, P.; Sundar, R.

10.1101/2024.03.21.585686 — cancer biology — Posted on 2024-03-28

646 Chitin synthase targeting antifungal agents for Mucormycosis (Black fungus disease) caused by Rhizopus delemar - An in-silico study

George, A. J.; B, V.; Nair, A. S.

10.1101/2024.03.26.586901 — bioinformatics — Posted on 2024-03-28

647 Cbf11 and Mga2 function as a single regulatory entity to activate transcription of lipid metabolism genes and promote mitotic fidelity in fission yeast

Maresova, A.; Grulyova, M.; Hradilova, M.; Zemlianski, V.; Princova, J.; Prevorovsky, M.

10.1101/2024.03.25.586586 — molecular biology — Posted on 2024-03-28

648 MftG is crucial for alcohol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

Gracïa, A. P.; Nikitushkin, V.; Ellerhorst, M.; Vilhena, C.; Klassert, T.; Starick, A.; Siemers, M.; Al-Jammal, W. K.; Vilotijevic, I.; Slevogt, H.; Papenfort, K.; Lackner, G.

10.1101/2024.03.26.586840 — microbiology — Posted on 2024-03-28

649 Base editing of Ptbp1 in neurons alleviates symptoms in a mouse model for Parkinson's disease

Boeck, D.; Wilhelm, M.; Mumenthaler, J.; Carpanese, D. F.; d'Aquin, S.; Cremonesi, A.; Rassi, A.; Haberle, J.; Patriarchi, T.; Schwank, G.

10.1101/2024.03.22.586274 — neuroscience — Posted on 2024-03-28

650 Generative Models for Prediction of Non-B DNA Structures

Cherednichenko, O.; Poptsova, M.

10.1101/2024.03.23.586408 — bioinformatics — Posted on 2024-03-28

651 In silico exploration of potent flavonoids for dengue therapeutics

Phunyal, A.; Adhikari Subin, J.; Adhikari, A.

10.1101/2024.03.24.586491 — bioinformatics — Posted on 2024-03-28

652 Conserved Lysine in transmembrane helix 5 is key for the inner gating of the LAT transporter BasC

Fort, J.; Nicolas-Arago, A.; Maggi, L.; Martinez-Molledo, M.; Kapiki, D.; Zijlstra, N.; Bodoy, S.; Pardon, E.; Steyaert, J.; Llorca, O.; Orozco, M.; Cordes, T.; Palacin, M.

10.1101/2024.03.26.586791 — biochemistry — Posted on 2024-03-28

653 Developmental stage determines the realized energy landscape for a flight specialist

Nourani, E.; Faure, L.; Bronnvik, H.; Scacco, M.; Bassi, E.; Fiedler, W.; Gruebler, M. U.; Hatzl, J.; Jenny, D.; Roverselli, A.; Sumasgutner, P.; Tschumi, M.; Wikelski, M.; Safi, K.

10.1101/2023.09.07.556633 — animal behavior and cognition — Posted on 2024-03-28

654 Fawn bedsite selection by a large ungulate living in a peri-urban area

Conteddu, K.; Wilson, K.; Amin, B.; Chari, S.; Haigh, A.; Griffin, L. L.; Quinn, M.; Ryan, A.; Smith, A. F.; Ciuti, S.

10.1101/2023.08.11.552922 — animal behavior and cognition — Posted on 2024-03-28

655 The dual role of the 16mer motif within the 3' untranslated region of the variant surface glycoprotein of Trypanosoma brucei

Bakari-Soale, M.; Batram, C.; Zimmermann, H.; Jones, N. G.; Engstler, M.

10.1101/2023.12.21.572740 — cell biology — Posted on 2024-03-28

656 Regulatory Dynamics of Sch9 in Response to Cytosolic Acidification: From Spatial Reconfiguration to Cellular Adaptation to Stresses

Fujii, R.; Takeda, E.; Itakura, E.; Matsuura, A.

10.1101/2024.03.12.584575 — cell biology — Posted on 2024-03-28

657 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species

Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.

10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-28

658 Human stem cell derived neurons and astrocytes to detect novel auto-reactive IgG signature in immune-mediated neurological diseases

Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.

10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-03-28

659 In-vivo whole-cortex estimation of excitation-inhibition ratio indexes cortical maturation and cognitive ability in youth

Zhang, S.; Larsen, B.; Sydnor, V. J.; Zeng, T.; An, L.; Yan, X.; Kong, R.; Kong, X.; Gur, R. C.; Gur, R. E.; Moore, T. M.; Wolf, D. H.; Holmes, A. J.; Xie, Y.; Zhou, J. H.; Fortier, M. V.; Tan, A. P.; Gluckman, P.; Chong, Y. S.; Meaney, M.; Deco, G.; Satterthwaite, T. D.; Yeo, B. T. T.

10.1101/2023.06.22.546023 — neuroscience — Posted on 2024-03-28

660 Overlapping Neural Correlates Underpin Theory of Mind and Semantic Cognition: Evidence from a Meta-Analysis of 344 Functional Neuroimaging Studies

Balgova, E.; Diveica, V.; Jackson, R. L.; Binney, R. J.

10.1101/2023.08.16.553506 — neuroscience — Posted on 2024-03-28

661 Functional characterization of Lipid storage droplets 1 (LSD1) in growth and lipolysis of Hermetia illucens

Jiang, Y.; Kou, Z.; Chen, B.; Huang, Y.

10.1101/2024.03.22.586280 — zoology — Posted on 2024-03-28

662 Red light perception by the root is essential for gibberellin-induced primary-root elongation in tomato

Ramon, U.; Adiri, A.; Cheriker, H.; Nir, I.; Borko, Y.; Weiss, D.

10.1101/2023.08.20.554010 — plant biology — Posted on 2024-03-28

663 CPT1A Mediates Radiation Sensitivity in Colorectal Cancer

Chen, Z.; Yu, L.; Zheng, Z.; Wang, X.; Guo, Q.; Chen, Y.; Zhang, Y.; Zhang, Y.; Xiao, J.; Chen, K.; Fan, H.; Ding, Y.

10.1101/2024.03.26.586752 — cancer biology — Posted on 2024-03-28

664 Effect of C-to-T transition at CpG sites on tumor suppressor genes in tumor development in cattle evaluated by somatic mutation analysis in enzootic bovine leukosis

Nishimori, A.; Andoh, K.; Matsuura, Y.; Okagawa, T.; Konnai, S.

10.1101/2024.03.19.585713 — cancer biology — Posted on 2024-03-28

665 A high-resolution haplotype pangenome uncovers somatic hybridization, recombination and intercontinental migration in oat crown rust

Henningsen, E.; Lewis, D.; Nazareno, E.; Huang, Y.-F.; Steffenson, B. J.; Boesen, B.; Kianian, S. F.; Stone, E.; Dodds, P.; Sperschneider, J.; Figueroa, M.

10.1101/2024.03.27.583983 — genomics — Posted on 2024-03-27

666 The plant specific cohesin subunit SYN4 contributes to 3D genome organization and activity

Paajanen, P.; Proksch, C.; Krueger, S.; Gorzolka, K.; Stellmach, H.; Ziegler, J.; Romeis, T.; Dodd, A. N.; Bomblies, K.; Handrick, V.

10.1101/2024.03.27.586521 — genetics — Posted on 2024-03-28

667 Targeted proteomics addresses selectivity and complexity of protein degradation by autophagy

Leytens, A.; FERNANDEZ, R. B.; GARCIA, C. J.; ROUBATY, C.; Stumpe, M.; BOYA, P.; Dengjel, J.

10.1101/2024.03.27.586977 — cell biology — Posted on 2024-03-28

668 Molecular basis for condensin enrichment at pericentromeres

Wang, M.; Zou, J.; Spanos, C.; Rappsilber, J.; Marston, A. L.

10.1101/2024.03.27.586992 — cell biology — Posted on 2024-03-28

669 Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.

Brambilla, E.; Yousuf, M.; Zhang, Q.; Mbemba, G.; Oeuvray, C.; Mektepbayeva, D.; Olliver, A.; Lagomarsino, M. C.; Sclavi, B.

10.1101/2024.03.27.586983 — cell biology — Posted on 2024-03-28

670 FilamentID reveals the composition and function of metabolic enzyme polymers during gametogenesis

Hugener, J.; Xu, J.; Wettstein, R.; Ioannidi, L.; Velikov, D.; Wollweber, F.; Henggeler, A.; Matos, J.; Pilhofer, M.

10.1101/2024.03.26.586525 — cell biology — Posted on 2024-03-28

671 Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.

Vora, S.; Andrew, A.; Kumar, R. P.; Nazareth, D.; Fernando, M.; Jones, M. J.; He, Y.; Hooper, J.; McMillan, N. A.; Urosevic, J.; Saeh, J.; Travers, J.; Gabrielli, B.

10.1101/2024.03.27.585450 — cell biology — Posted on 2024-03-28

672 Membrane curvature association of amphipathic helix 8 drives constitutive GPCR endocytosis

Herlo, R.; Schmidt, J. H.; Rombach, J.; Larsen, A. H.; Stoklund, M.; Perslev, M.; Nielsen, T. T. E.; Andersen, K. A.; Herenbrink, C.; Lycas, M. D.; Ejdrup, A.; Christensen, N.; Christensen, J. P.; Salman, M.; Herborg, F.; Gether, U.; Hauser, A.; Bassereau, P.; Perrais, D.; Madsen, k. L.

10.1101/2024.03.27.587027 — cell biology — Posted on 2024-03-28

673 Age pigment lipofuscin causes oxidative stress, lysosomal dysfunction, and pyroptotic cell death

Baldensperger, T.; Jung, T.; Heinze, T.; Schwerdtle, T.; Hoehn, A.; Grune, T.

10.1101/2024.03.25.586520 — cell biology — Posted on 2024-03-28

674 Tau phosphorylation impedes functionality of protective tau envelopes

Lansky, Z.; Siahaan, V.; Weissova, R.; Lanska, E.; Karhanova, A.; Dostal, V.; Henriot, V.; Janke, C.; Libusova, L.; Braun, M.; Balastik, M.

10.1101/2024.03.25.586522 — cell biology — Posted on 2024-03-28

675 SMYD1-mediated Mono-Methylation of Lysine K35 of the sarcomeric Myosin Heavy Chain (MHC) is fundamental for thick filament assembly in zebrafish and human iPSC-derived cardiomyocytes

Diofano, F.; Amadi, C.; Gahr, B.; Weinmann-Emhardt, K.; Rottbauer, W.; Just, S.

10.1101/2024.03.27.585692 — molecular biology — Posted on 2024-03-28

676 Loss of the Familial Dysautonomia gene Elp1 in cerebellar granule cell progenitors leads to ataxia in mice

Manz, F.; da Silva, P. B. G.; Schouw, M. E.; Lukasch, C.; Bianchini, L.; Sieber, L.; Garcia-Lopez, J.; Ahmad, S. T.; Li, Y.; Lin, H.; Joshi, P.; Spaenig, L.; Rados, M.; Roiuk, M.; Sepp, M.; Zuckermann, M.; Northcott, P. A.; Patrizi, A.; Kutscher, L. M.

10.1101/2024.03.27.586801 — neuroscience — Posted on 2024-03-27

677 Probe-dependent Proximity Profiling (ProPPr) Uncovers Similarities and Differences in Phospho-Tau-Associated Proteomes Between Tauopathies

Morderer, D.; Wren, M. C.; Liu, F.; Kouri, N.; Maistrenko, A.; Khalil, B.; Salemi, M. R.; Phinney, B. S.; Dickson, D. W.; Murray, M. E.; Rossoll, W.

10.1101/2024.03.25.585597 — neuroscience — Posted on 2024-03-28

678 Development and Organization of the Retinal Orientation Selectivity Map

Vita, D. J.; Orsi, F. S.; Stanko, N. G.; Clark, N. A.; Tiriac, A.

10.1101/2024.03.27.585774 — neuroscience — Posted on 2024-03-28

679 Resource allocation in biochemically structured metabolic networks

Seeger, L. A.; Pinheiro, F.; Lässig, M.

10.1101/2024.03.27.586223 — systems biology — Posted on 2024-03-27

680 Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance.

Segeren, H. A.; Wierenga, K.; Riemers, F. M.; van Liere, E. A.; Westendorp, B.

10.1101/2024.03.26.585806 — cancer biology — Posted on 2024-03-28

681 Dual-view jointly learning improves personalized drug synergy prediction

Li, X.; Shen, B.; Feng, F.; Li, K.; Ma, L.; Li, H.

10.1101/2024.03.27.586892 — cancer biology — Posted on 2024-03-28

682 NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model

MERAZ, I. M.; Majidi, M.; Song, R.; Meng, F.; Gao, L.; Wang, Q.; Wang, J.; Shpall, E. J.; Roth, J. A.

10.1101/2024.03.26.586829 — cancer biology — Posted on 2024-03-28

683 The lipid droplet protein DHRS3 is a regulator of melanoma cell state

Johns, E.; Ma, Y.; Louphrasitthipol, P.; Peralta, C.; Hunter, M. V.; Raymond, J. H.; Molina, H.; Goding, C. R.; White, R. M.

10.1101/2024.03.25.586589 — cancer biology — Posted on 2024-03-28

684 A 3D in vitro assay to study combined immune cell infiltration and cytotoxicity

Crawford, A. J.; Johnston, A.; Du, W.; Hanna, E. A.; Schell, D.; Wan, Z.; Chen, T.-H.; Wu, F.; Ren, K.; Lim, Y.; Nair, P. R.; Wirtz, D.

10.1101/2024.03.27.586980 — cancer biology — Posted on 2024-03-28

685 HNF&alpha is a target of the Wnt/beta-catenin pathway and regulates colorectal carcinogenesis

Sang, L.; Bai, W.; Lu, C.; Dong, R.; Hao, Q.; Zhang, Y.; Sun, R.; Shen, J.; Sun, Y.; Sun, J.

10.1101/2024.03.25.586542 — cancer biology — Posted on 2024-03-28

686 Mutational synergy with CREBBP loss in lymphomagenesis identified through forward insertional mutagenesis in a new DLBCL mouse model

Sakakini, N.; Straver, R.; Azazi, D.; Horton, S. J.; Asby, R.; Richardson, S. E.; Madrigal, P.; Soilleux, E. E.; Bashford-Rogers, R. J. M.; de Ridder, J.; Huntly, B. J. P.

10.1101/2024.03.25.586554 — cancer biology — Posted on 2024-03-28

687 ANP32E drives vulnerability to ATR inhibitors by inducing R-loops-dependent Transcription Replication Conflicts in Triple Negative Breast Cancer

Lago, S.; Poli, V.; Fol, L.; Botteon, M.; Fasciani, A.; Turdo, A.; Gaggianesi, M.; Todaro, M.; Ciani, Y.; D Amato, G.; Demichelis, F.; Zippo, a.

10.1101/2024.03.25.586539 — cancer biology — Posted on 2024-03-28

688 Advancing CAR T-Cell Therapy: Simultaneously Attack Tumor and Immunosuppressive Cells in the Tumor Microenvironment

Luo, Y.; Garavito, E. S.; Brooks, M. M.; Gadd, M. E.; Qie, Y.; Navas, M. J. U.; Hundal, T.; Li, S.; Lopez, A. O.; Jones, V. K.; Lou, Y.; Patel, T.; Dronca, R.; Kharfan-Dabaja, M. A.; Dong, H.; Quinones-Hinojosa, A.; Qin, H.

10.1101/2024.03.25.586653 — cancer biology — Posted on 2024-03-28

689 Stable and Oscillatory Hypoxia Differentially Regulate Invasibility of Breast Cancer Associated Fibroblasts

Du, W.; Liu, Y.; Afzal, J.; Liu, S.; Suhail, Y.; Kshitiz,

10.1101/2024.03.26.586706 — cancer biology — Posted on 2024-03-28

690 Fatty acids are not a significant contributor to the TCA cycle in cancer cell lines: evidence of incomplete fatty acid oxidation.

Santiappillai, N. T.; Hakeem-Sanni, M. F.; Ghasemi, M.; Withy, A.; Quek, L.-E.; Hoy, A. J.

10.1101/2024.03.25.586547 — cancer biology — Posted on 2024-03-28

691 Androgen deprivation therapy-resistant club cells are linked to myeloid cell-driven immunosuppression in the prostate tumor microenvironment

Kiviaho, A.; Eerola, S. K.; Kallio, H. M. L.; Andersen, M. K.; Spotbeen, X.; Giesen, A.; Parker, C. T. A.; Taavitsainen, S.; Hantula, O.; Marttinen, M.; Hermelo, I.; Ismail, M.; Midtbust, E.; Wess, M.; Devlies, W.; Sharma, A.; Krossa, S.; Hakkinen, T.; Afyounian, E.; Kesseli, J.; Tolonen, T.; Tammela, T. L. J.; Viset, T.; Storkersen, O.; Giskeodegord, G. F.; Rye, M. B.; Murtola, T.; Latonen, L.; Bova, G. S.; Mills, I. G.; Joniau, S.; Swinnen, J. V.; Mirtti, T.; Attard, G.; Claessens, F.; Visakorpi, T.; Rautajoki, K. J.; Tessem, M.-B.; Urbanucci, A.; Nykter, M.

10.1101/2024.03.25.586330 — cancer biology — Posted on 2024-03-28

692 YTHDC1 m6A-dependent and m6A-independent functions converge to preserve DNA damage response.

Elvira-Blazquez, D.; Fernandez-Justel, J.; Arcas, A.; Statello, L.; Goni, E.; Gonzalez, J.; Ricci, B.; Zaccara, S.; Raimondi, I.; Huarte, M.

10.1101/2024.03.25.586632 — cancer biology — Posted on 2024-03-28

693 Novel synthetic ecteinascidins exhibit potent anti-melanoma activity by suppressing super-enhancer-driven oncogenic transcription

Coin, F.

10.1101/2024.03.26.586754 — cancer biology — Posted on 2024-03-28

694 Hypercholesterolemia-induced impairment in sorafenib functionality is overcome by avasimibe co-treatment

Athavale, D.; Yaduvanshi, H.; Bhati, F. K.; Mayengbam, S. S.; More, T.; Rapole, S.; Bhat, M. K.

10.1101/2024.03.27.586757 — cancer biology — Posted on 2024-03-28

695 A Novel Liver Cancer-Selective Histone Deacetylase Inhibitor Is Effective Against Hepatocellular Carcinoma and Induces Durable Responses with Immunotherapy

Wu, B.; Tapadar, S.; Ruan, Z.; Sun, C.; Arnold, R.; Olugbami, J.; Johnston, A.; Arunsi, U.; Gaul, D.; Petros, J.; Kobayashi, T.; Duda, D. G.; Oyelere, A. K.

10.1101/2024.03.27.587062 — cancer biology — Posted on 2024-03-28

696 PTEN and ARID1A haploinsufficiency equip colonic epithelium for oncogenic transformation

Skoufou-Papoutsaki, N.; Adler, S.; Mehmed, S.; Tume, C.; Olpe, C.; Morrissey, E.; Kemp, R.; Girard, A.-C.; Moutin, E. B.; Chilamakuri, C. S. R.; Miller, J. L.; Lindskog, C.; Werle, F.; Marks, K.; Perrone, F.; Zilbauer, M.; Tourigny, D. S.; Winton, D. J.

10.1101/2024.03.27.586939 — cancer biology — Posted on 2024-03-28

697 Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon

Araiza-Olivera, D.; Prudnikova, T. Y.; Uribe-Alvarez, C.; Cai, K. Q.; Franco-Barraza, J.; Dones, J. M.; Raines, R.; Chernoff, J.

10.1101/2024.03.27.587019 — cancer biology — Posted on 2024-03-28

698 Molecular dynamics unveils multiple-site binding of inhibitors with reduced activity on the surface of dihydrofolate reductase

Araki, M.; Ekimoto, T.; Takemura, K.; Matsumoto, S.; Tamura, Y.; Kokubo, H.; Bekker, G.-J.; Yamane, T.; Isaka, Y.; Sagae, Y.; Kamiya, N.; Ikeguchi, M.; Okuno, Y.

10.1101/2024.03.27.586990 — biophysics — Posted on 2024-03-28

699 Calculating Structure Factors of Protein Solutions by Atomistic Modeling of Protein-Protein Interactions

Qin, S.; Zhou, H.-X.

10.1101/2024.03.27.587040 — biophysics — Posted on 2024-03-28

700 The Drosophila RNA binding protein Hrp48 binds a specificRNA sequence of the msl-2 mRNA 3' UTR to regulatetranslation

Lomoschitz, A.; Meyer, J.; Guitart, T.; Krepl, M.; Lapouge, K.; Hayn, C.; Schweimer, K.; Simon, B.; Sponer, J.; Gebauer, F.; Hennig, J.

10.1101/2024.03.26.586676 — biophysics — Posted on 2024-03-28

701 Evaluation of intracochlear pressure and distribution during fluid application in cochlea models and human petrous bone

Kim, R.; Riemann, C.; Kilgue, A.; Schleyer, S.; Pfeiffer, C. J.; Scholtz, L.-U.; Schuermann, M.; Todt, I.

10.1101/2024.03.25.586533 — biophysics — Posted on 2024-03-28

702 Theoretical insights into rotary mechanism of MotAB in the bacterial flagellar motor

Kubo, S.; Okada, Y.; Takada, S.

10.1101/2024.03.25.586605 — biophysics — Posted on 2024-03-28

703 Open and closed conformations of a sub-80 kDa Chagas vaccine candidate defined by a cryo-EM led integrative approach

Batra, S.; Ragan, T. J.; Frank, A. M.; Kaplan, M.; Lancey, C.; Assadipapari, M.; Ying, C.; Struwe, W. B.; Hesketh, E.; Barfod, L.; Campeotto, I.

10.1101/2024.03.26.586384 — biophysics — Posted on 2024-03-28

704 The Hill function is the universal Hopfield barrier for sharpness of input-output responses

Martinez-Corral, R.; Nam, K.-M.; DePace, A. H.; Gunawardena, J.

10.1101/2024.03.27.587054 — biophysics — Posted on 2024-03-28

705 The Molecular Architecture of the Nuclear Basket

Singh, D.; Soni, N.; Hutchings, J.; Echeverria, I.; Shaikh, F.; Duquette, M.; Suslov, S.; Li, Z.; van Eeuwen, T.; Molloy, K.; Shi, Y.; Wang, J.; Guo, Q.; Chait, B. T.; Fernandez-Martinez, J.; Rout, M. P.; Sali, A.; Villa, E.

10.1101/2024.03.27.587068 — biophysics — Posted on 2024-03-28

706 STORMM: Structure and TOpology Replica Molecular Mechanics for chemical simulations

Cerutti, D. S.; Boothroyd, S.; Wiewiora, R.; Sherman, W.

10.1101/2024.03.27.587048 — biophysics — Posted on 2024-03-28

707 Macromolecular interactions and geometrical confinement determine the 3D diffusion of ribosome-sized particles in live Escherichia coli cells

Valverde-Mendez, D.; Sunol, A. M.; Bratton, B. P.; Delarue, M.; Hofmann, J. L.; Sheehan, J. P.; Gitai, Z.; Holt, L. J.; Shaevitz, J. W.; Zia, R. N.

10.1101/2024.03.27.587083 — biophysics — Posted on 2024-03-28

708 Development of a generalisable tryptophan-optimised quenchbody biosensor based on a synthetic nanobody library

Cater, J. H.; Elsalamouny, N.; Mansour, G. H.; Hutchinson, S.; Mc Guinness, C.; Mueller, S. H.; Spinks, R. R.; Shanmugam, N.; Pichard-Kostuch, A.; Ghodke, H.; Ribezzi-Crivellari, M.; Yu, H.; van Oijen, A. M.; Griffiths, A. D.; Spenkelink, L. M.

10.1101/2024.03.27.582625 — bioengineering — Posted on 2024-03-27

709 The white matter fiber tract deforms most in the perpendicular direction during in vivo volunteer impacts

Zhou, Z.; Olsson, C.; Gasser, T. C.; Li, X.; Kleiven, S.

10.1101/2024.03.26.585293 — bioengineering — Posted on 2024-03-27

710 Design and Evaluation of Nanoscale Materials with Programmed Responsivity towards Epigenetic Enzymes

Ray, P.; Sedigh, A.; Confeld, M.; Alhalhooly, L.; Iduoku, K.; Casanola-Martin, G.; Pham-The, H.; Rasulev, B.; Choi, Y.; Yang, Z.; Mallik, S.; Quadir, M.

10.1101/2024.03.26.585429 — bioengineering — Posted on 2024-03-27

711 Targeting protein-ligand neosurfaces using a generalizable deep learning approach

Marchand, A.; Buckley, S.; Schneuing, A.; Pacesa, M.; Gainza, P.; Elizarova, E.; Neeser, R. M.; Lee, P.-W.; Reymond, L.; Elia, M.; Scheller, L.; Georgeon, S.; Schmidt, J.; Schwaller, P.; Maerkl, S. J.; Bronstein, M.; Correia, B. E.

10.1101/2024.03.25.585721 — biochemistry — Posted on 2024-03-28

712 Engineering Substrate Channeling in Assembly-Line Terpene Biosynthesis

Wenger, E. S.; Schultz, K.; Marmorstein, R.; Christianson, D. W.

10.1101/2024.03.25.586617 — biochemistry — Posted on 2024-03-28

713 Absolute quantification of rare gene targets in limited samples using crude lysate and ddPCR

Kaur, C.; Adams, S.; Kibirige, C. N.; Asquith, B.

10.1101/2024.03.27.586936 — biochemistry — Posted on 2024-03-28

714 The structure of the R2T complex reveals a different architecture of the related HSP90 co-chaperones R2T and R2TP

Palacios-Abella, A.; Lopez-Perrote, A.; Boskovic, J.; Fonseca, S.; Urbez, C.; Rubio, V.; Llorca, O.; Alabadi, D.

10.1101/2024.03.27.587014 — biochemistry — Posted on 2024-03-28

715 Intron-loss in Kinetoplastea correlates with a non-functional EJC and loss of NMD factors

Gabiatti, B. P.; Freire, E. R.; Odenwald, J.; Holetz, F.; Carrington, M.; Kramer, S.; Zoltner, M.

10.1101/2024.03.25.586568 — biochemistry — Posted on 2024-03-28

716 Identification and characterization of nanobodies acting as molecular chaperones for glucocerebrosidase through a novel allosteric mechanism

Dal Maso, T.; Sinisgalli, C.; Zilio, G.; Tessari, I.; Pardon, E.; Steyaert, J.; Ballet, S.; Greggio, E.; Versees, W.; Plotegher, N.

10.1101/2024.03.25.586126 — biochemistry — Posted on 2024-03-28

717 Trafficking of Connexin36 (Cx36) in the early secretory pathway

Tetenborg, S.; Ariakia, F.; Martinez-Soler, E.; Shihabeddin, E.; Lazart, I. C.; Miller, A. C.; O'Brien, J.

10.1101/2024.03.25.586643 — biochemistry — Posted on 2024-03-28

718 Nematocida displodere Mechanosensitive Ion Channel of Small Conductance 2 assembles into a unique 6-channel super-structure in vitro

Berg, A.; Berntsson, R. P.-A.; Barandun, J.

10.1101/2024.03.27.587072 — biochemistry — Posted on 2024-03-28

719 TRAIP plays an essential role in the dissociation of PCNA from chromatin during mitosis, required to precise DNA replication initiation

Shiomi, Y.; Saito, Y.; Kanemaki, M. T.; Nishitani, H.

10.1101/2023.05.08.539800 — molecular biology — Posted on 2024-03-28

720 Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients

Azimi, M.; Cho, S.; Bozkurt, E.; McDonough, E.; Kisakol, B.; Matveeva, A.; Salvucci, M.; Dussmann, H.; Firat, C.; Urganci, N.; Shia, J.; McDade, S.; Longley, D. B.; Ginty, F.; Prehn, J. H. M.

10.1101/2024.01.30.577720 — cancer biology — Posted on 2024-03-28

721 Biolearn, an open-source library for biomarkers of aging

Ying, K.; Paulson, S.; Eames, A.; Li, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Gobel, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.

10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-28

722 Bioenergetic mapping of 'healthy microbiomes' via compound processing potential imprinted in gut and soil metagenomes

Liddicoat, C.; Edwards, R. A.; Roach, M. J.; Robinson, J. M.; Wallace, K. J.; Barnes, A. D.; Brame, J.; Heintz-Buschart, A.; Cavagnaro, T. R.; Dinsdale, E. A.; Doane, M. P.; Eisenhauer, N.; Mitchell, G.; Rai, B.; Ramesh, S.; Breed, M. F.

10.1101/2023.11.05.565728 — bioinformatics — Posted on 2024-03-28

723 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.

10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-03-28

724 Genome-wide co-essentiality analysis in Mycobacterium tuberculosis reveals an itaconate defense enzyme module

Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Wu, A. M.; Almada-Monter, R.; Smith, C. M.; Rhee, K. Y.

10.1101/2022.09.27.509804 — microbiology — Posted on 2024-03-28

725 Bridging Neurons and Behavior in a Convolutional Neural Network with Emergent Human-like Covert Attention

Srivastava, S.; Wang, W. Y.; Eckstein, M. P.

10.1101/2023.09.17.558171 — neuroscience — Posted on 2024-03-28

726 Small extracellular vesicles promote stiffness-mediated metastasis

Sneider, A.; Liu, Y.; Starich, B.; Du, W.; Marar, C.; Faqih, N.; Ciotti, G. E.; Kim, J. H.; Krishnan, S.; Ibrahim, S.; Igboko, M.; Locke, A.; Lewis, D. M.; Hong, H.; Karl, M.; Vij, R.; Russo, G. C.; Nair, P. R.; Gomez-de-Mariscal, E.; Habibi, M.; Munoz-Barrutia, A.; Gu, L.; Eisinger-Mathason, T. S. K.; Wirtz, D.

10.1101/2023.07.01.545937 — cancer biology — Posted on 2024-03-28

727 From Noise to Knowledge: Probabilistic Diffusion-Based Neural Inference of Gene Regulatory Networks

Zhu, H.; Slonim, D. K.

10.1101/2023.11.05.565675 — bioinformatics — Posted on 2024-03-28

728 Refining the pool of RNA-binding domains advances the classification and prediction of RNA-binding proteins

Wassmer, E.; Koppany, G.; Hermes, M.; Diederichs, S.; Caudron-Herger, M.

10.1101/2023.08.17.553134 — bioinformatics — Posted on 2024-03-27

729 Predictive modeling provides insight into the clinical heterogeneity associated with TARS1 loss-of-function mutations

Meyer-Schuman, R.; Cale, A. R.; Pierluissi, J. A.; Jonatzke, K. E.; Park, Y. N.; Lenk, G. M.; Oprescu, S. N.; Grachtchouk, M. A.; Dlugosz, A. A.; Beg, A. A.; Meisler, M. H.; Antonellis, A.

10.1101/2024.03.25.586600 — genetics — Posted on 2024-03-27

730 Identification of candidate causal cis-regulatory variants underlying electrocardiographic QT interval GWAS loci

Kadagandla, S.; Kapoor, A.

10.1101/2024.03.13.584880 — genetics — Posted on 2024-03-27

731 Identification of stress specific autophagy regulators from tandem CRISPR screens

Losier, T. T.; Rousseaux, M. W. C.; Russell, R. C.

10.1101/2024.03.27.587008 — cell biology — Posted on 2024-03-27

732 Analysis of gliomas DNA methylation: Assessment of pre-analytical variables.

Bomsztyk, K.; Mar, D.; Denisenko, O.; Powell, S.; Vishnoi, M.; Delegard, J.; Patel, A.; Ellenbogen, R.; Ramakrishna, R.; Rostomily, R.

10.1101/2024.03.26.586350 — molecular biology — Posted on 2024-03-27

733 Single-cell transcriptomics identifies a p21-activated kinase important for survival of the zoonotic parasite Fasciola hepatica

Puckelwaldt, O.; Gramberg, S.; Ajmera, S.; Koepke, J.; Samakovlis, C.; Haeberlein, S.

10.1101/2024.03.26.586785 — molecular biology — Posted on 2024-03-27

734 Intron-lariat spliceosomes convert lariats to true circles: implications for intron transposition

Ares, M.; Igel, A. H.; Katzman, S.; Donohue, J. P.

10.1101/2024.03.26.586863 — molecular biology — Posted on 2024-03-27

735 Global variation in prior exposure shapes antibody neutralization profiles of SARS-CoV-2 variants up to BA.2.86

Turner, S.; Amirthalingam, G.; Bailey, D.; Barouch, D. H.; Bewley, K. R.; Brown, K.; Cao, Y. R.; Chan, Y.-W.; Charlton, S.; DOVE consortium, ; Coombes, N. S.; Hallis, B.; Ho, D. D.; Jian, F.; Lasrado, N.; Lassauniere, R.; Lihong, L.; Montefiori, D. C.; Moss, P.; Newman, J.; Parry, H.; Polacek Strandh, C.; Rasmussen, M.; Shao, F.; Shen, X.; Thakur, N.; Thomson, E. C.; Wang, J.; Wang, P.; Wang, Q. C.; Willett, B. J.; Yisimayi, A.; Smith, D. J.

10.1101/2024.03.27.586820 — immunology — Posted on 2024-03-27

736 Type 1 diabetes and parasite infection: an exploratory study in the NOD mouse

Giraud, E.; Fiette, L.; Melanitou, E.

10.1101/2024.03.27.586975 — immunology — Posted on 2024-03-27

737 Multisensory integration of social signals by a pathway from the basal amygdala to the auditory cortex in maternal mice

Nowlan, A. C.; Choe, J.; Ansari, H. J.; Kelahan, C.; Shea, S. D.

10.1101/2022.02.17.480854 — neuroscience — Posted on 2024-03-27

738 High density linkage to physical mapping in a unique Tall x Dwarf Coconut (Cocos nucifera L.) outbred F2 uncovers a major QTL for flowering time colocalized with the FLOWERING LOCUS T (FT)

Grattapaglia, D.; Alves, W. B. d. S.; Pacheco, C. A. P.

10.1101/2024.01.31.578260 — plant biology — Posted on 2024-03-27

739 Molecular Basis for RNA Cytidine Acetylation by NAT10

Zhou, M.; Gamage, S. T.; Tran, K.; Bartee, D.; Wei, X.; Yin, B.; Berger, S.; Meier, J. L.; Marmorstein, R.

10.1101/2024.03.27.587050 — biophysics — Posted on 2024-03-27

740 Assembling bacterial puzzles: piecing together functions into microbial pathways

Chung, H.; Friedberg, I.; Bromberg, Y.

10.1101/2024.03.27.587058 — bioinformatics — Posted on 2024-03-27

741 Maptcha: An efficient parallel workflow for hybrid genome scaffolding

Bhowmik, O.; Rahman, T.; Kalyanaraman, A.

10.1101/2024.03.25.586701 — bioinformatics — Posted on 2024-03-27

742 Structural basis for recognition of the FLAG-1 tag by anti-FLAG M2

Beugelink, J. W.; Sweep, E.; Janssen, B. J. C.; Snijder, J.; Pronker, M. F.

10.1101/2024.03.25.586599 — biochemistry — Posted on 2024-03-27

743 Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation

10.1101/2024.03.27.586925 — biochemistry — Posted on 2024-03-27

744 A benchmarked, high-efficiency prime editing platform for multiplexed dropout screening

Cirincione, A.; Simpson, D.; Ravisankar, P.; Solley, S. C.; Yan, J.; Singh, M.; Adamson, B.

10.1101/2024.03.25.585978 — genomics — Posted on 2024-03-27

745 Sequential-GAM constructs the single-cell geometric 3D genome structure

Li, Y.; Wang, K.; Shi, M.; Zhang, M. Q.; Gao, J.

10.1101/2024.03.27.586762 — genomics — Posted on 2024-03-27

746 Transcript-specific enrichment enables profiling rare cell states via scRNA-seq

Abay, T.; Stickels, R. R.; Takizawa, M. T.; Nalbant, B. N.; Hsieh, Y.-H.; Hwang, S.; Snopkowski, C.; Yu, K. K. H.; Abou-Mrad, Z.; Tabar, V.; Ludwig, L. S.; Chaligne, R.; Satpathy, A. T.; Lareau, C. A.

10.1101/2024.03.27.587039 — genomics — Posted on 2024-03-27

747 Metal fluorides - multi-functional tools for the study of phosphoryl transfer enzymes

Pellegrini, E.; Juyoux, P.; von Velsen, J.; Baxter, N.; Jin, Y.; Dannatt, H.; Cliff, M.; Waltho, J.; Bowler, M. W.

10.1101/2024.03.25.586559 — molecular biology — Posted on 2024-03-27

748 Matrisome gene expression is altered during non-allometric heart growth in genetically enlarged Drosophila

Andrews, R. M.; Jacobs, J. R.

10.1101/2024.03.25.586620 — molecular biology — Posted on 2024-03-27

749 Proteome analysis provides insights into sex differences in Holothuria Scabra

Cheng, C.; Wu, F.; Xu, Y.; Ren, C.; Chen, T.; Li, S.; Shen, P.; Jiang, F.

10.1101/2024.03.26.586852 — molecular biology — Posted on 2024-03-27

750 Circular RNA aptamers ameliorate AD-relevant phenotypes by targeting PKR

Feng, X.; Jiang, B.-W.; Zhai, S.-N.; Liu, C.-X.; Wu, H.; Zhu, B.-Q.; Wei, M.-Y.; Wei, J.; Yang, L.; Chen, L.-L.

10.1101/2024.03.27.583257 — molecular biology — Posted on 2024-03-27

751 Outer membrane vesicles can contribute to cellulose degradation in Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms

Gasser, M. T.; Liu, A.; Altamia, M. A.; Bresinger, B.; Brewer, S. L.; Flatau, R.; Hancock, E.; Preheim, S. P.; Filone, C. M.; Distel, D. L.

10.1101/2024.03.27.587001 — microbiology — Posted on 2024-03-27

752 The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

Baker, P. J.; Bohrer, A. C.; Castro, E.; Amaral, E. P.; Snow-Smith, M.; Torres-Juarez, F.; Gould, S. T.; Queiroz, A. T.; Fukutani, E. R.; Jordan, C. M.; Khillan, J. S.; Cho, K.; Barber, D. L.; Andrade, B. B.; Johnson, R. F.; Hilligan, K. L.; Mayer-Barber, K. D.

10.1101/2024.03.27.586885 — immunology — Posted on 2024-03-27

753 Fast burst fraction transients convey information independent of the firing rate

Naud, R.; Wang, X.; Friedenberger, Z.; Payeur, A.; Shin, J. N.; Beique, J.-C.; Richards, B.; Drüke, M.; Larkum, M.; Doron, G.

10.1101/2022.10.07.511138 — neuroscience — Posted on 2024-03-27

754 AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease

Kim, Y. S.; CHOI, S.-H.; Kim, K.-Y.; Navia Pelaez, J. M.; Perkins, G. A.; Choi, S.; Nazarenkov, N.; Kim, J.; Ju, W.; Rissman, R. A.; Ellisman, M. H.; Miller, Y. I.

10.1101/2024.02.16.580751 — neuroscience — Posted on 2024-03-27

755 Unlocking Precision Gene Therapy: Harnessing AAV Tropism with Nanobody Swapping at Capsid Hotspots

Hoffmann, M. D.; Gallant, J. P.; LeBeau, A. M.; Schmidt, D.

10.1101/2024.03.27.587049 — synthetic biology — Posted on 2024-03-27

756 ComPRePS: An Automated Cloud-based Image Analysis tool to democratize AI in Digital Pathology

Mimar, S.; Paul, A. S.; Lucarelli, N.; Boarder, S.; Santo, B. A.; Naglah, A.; Barisoni, L.; Hodgin, J.; Rosenberg, A.; Clapp, W.; Sarder, P.; for the Kidney Precision Medicine Project,

10.1101/2024.03.21.586102 — pathology — Posted on 2024-03-27

757 Cancer cell - fibroblast crosstalk via HB-EGF/EGFR/MEK signalling promotes macrophage recruitment in squamous cell carcinoma

Giangreco, G.; Rullan, A.; Naito, Y.; Biwas, D.; Liu, Y.-H.; Hooper, S.; Nenclares, P.; Bhide, S.; Cheang, M.; Chakravarty, P.; Hirata, E.; Swanton, C.; Melcher, A.; Harrington, K.; Sahai, E.

10.1101/2023.07.13.548733 — cancer biology — Posted on 2024-03-27

758 Dynamic binding of the bacterial chaperone Trigger factor to translating ribosomes

Havermark, T.; Metelev, M.; Lundin, E.; Volkov, I. L.; Johansson, M.

10.1101/2024.03.27.586930 — biophysics — Posted on 2024-03-27

759 MIDASim: a fast and simple simulator for realistic microbiome data

He, M.; Zhao, N.; Satten, G.

10.1101/2023.03.23.533996 — bioinformatics — Posted on 2024-03-27

760 MelAnalyze: Fact-Checking Melatonin claims using Large Language Models and Natural Language Inference

Palaniappan, S. K.; Karkera, N.; Ghosh, S.; Escames, G.

10.1101/2024.03.21.586201 — bioinformatics — Posted on 2024-03-27

761 PhosX: data-driven kinase activity inference from phosphoproteomics experiments

Lussana, A.; Petsalaki, E.

10.1101/2024.03.22.586304 — bioinformatics — Posted on 2024-03-27

762 Carbohydrate-active enzymes from Akkermansia muciniphila breakdown mucin O-glycans to completion

Crouch, L. I.; Bakshani, C. R.; Ojuri, T. O.; Pilgaard, B.; Holck, J.; McInnes, R.; Zakhour, M.; Kerouedan, M.; Newton, E.; Bolam, D. N.

10.1101/2024.03.27.586211 — biochemistry — Posted on 2024-03-27

763 mtDNA "Nomenclutter" and its Consequences on the Interpretation of Genetic Data

Bajic, V.; Schulmann, V. H.; Nowick, K.

10.1101/2023.11.19.567721 — genetics — Posted on 2024-03-27

764 Simulating animal movement trajectories from temporally dynamic step selection functions

Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.

10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-27

765 Roles for RERE in lymphatic endothelial cell proliferation and survival, and human cystic lymphatic malformations

Rogerson, D. M.; Muley, A.; Vogel, Z.; Giordano, J.; Wapner, R.; Shawber, C.

10.1101/2024.03.24.586490 — cell biology — Posted on 2024-03-27

766 Towards Targeted Protein Degradation in Escherichia coli - depletion of the essential GroEL protein using CLIPPERs.

Izert-Nowakowska, M. A.; Klimecka, M. M.; Antosiewicz, A.; Wroblewski, K.; Bandyra, K. J.; Goral, T. K.; Kmiecik, S.; Serwa, R. A.; Gorna, M. W.

10.1101/2024.02.29.582761 — molecular biology — Posted on 2024-03-27

767 Analytical Methods and Platforms for circRNA Vector Engineering to Improve Circularization Efficiency

Sun, Y.; Khimani, A. H.; Tong, Y.; Lu, Z.-x.

10.1101/2024.03.25.586602 — molecular biology — Posted on 2024-03-27

768 A Novel Dual Probe-based Method for Mutation Detection using Isothermal Amplification

Nandu, N.; Miller, M.; Tong, Y.; Lu, Z.-x.

10.1101/2024.03.27.586979 — molecular biology — Posted on 2024-03-27

769 In vivo Assembly of Bacterial Partition Condensates on Supercoiled and Linear DNA

Sekkouri Alaoui, H.; Quebre, V.; Delimi, L.; Rech, J.; Debaugny-Diaz, R.; Labourdette, D.; Campos, M.; Cornet, F.; Walter, J.-C.; Bouet, J.-Y.

10.1101/2024.03.26.585537 — molecular biology — Posted on 2024-03-27

770 Tangled genetic relationships within the Fusobacterium genus

Molteni, C.; Forni, D.; Cagliani, R.; Sironi, M.

10.1101/2024.03.27.587012 — microbiology — Posted on 2024-03-27

771 Loss of LasR function leads to decreased repression of Pseudomonas aeruginosa PhoB activity at physiological phosphate concentrations

Conaway, A.; Todorovic, I.; Mould, D. L.; Hogan, D. A.

10.1101/2024.03.27.586856 — microbiology — Posted on 2024-03-27

772 Altruistic feeding and cell-cell signaling during bacterial differentiation actively enhance phenotypic heterogeneity

Updegrove, T. B.; Delerue, T.; Anantharaman, V.; Cho, H.; Chan, C.; Nipper, T.; Choo-Wosoba, H.; Jenkins, L.; Zhang, L.; Su, Y.; Shroff, H.; Chen, J.; Bewley, C.; Aravind, L.; Ramamurthi, K. S.

10.1101/2024.03.27.587046 — microbiology — Posted on 2024-03-27

773 Extracellular biosynthesis of silver nanoparticles using cell suspension of Rhodococcus fascians

Ghadamgahi, F.; Konakalla, N. C.; Atash, M. M. S.; Ortiz, R.; Vetukuri, R. R.

10.1101/2024.03.27.587053 — microbiology — Posted on 2024-03-27

774 Identifying immune signatures of common exposures through co-occurrence of T-cell receptors in tens of thousands of donors

May, D. H.; Woodhouse, S.; Zahid, H. J.; Elyanow, R.; Doroschak, K.; Noakes, M. T.; Taniguchi, R.; Yang, Z.; Grino, J.; Byron, R.; Oaks, J.; Sherwood, A.; Greissl, J.; Chen-Harris, H.; Howie, B.; Robins, H. S.

10.1101/2024.03.26.583354 — immunology — Posted on 2024-03-27

775 Separating cognitive and motor processes in the behaving mouse

Hasnain, M. A.; Birnbaum, J. E.; Nunez, J. L. U.; Hartman, E.; Chandrasekaran, C.; Economo, M. N.

10.1101/2023.08.23.554474 — neuroscience — Posted on 2024-03-27

776 Cyanamide-inducible expression of homing nuclease I-SceI for iterative genome engineering and parallel promoter characterisation in Saccharomyces cerevisiae

McDonnell, L.; Evans, S.; Lu, Z.; Suchoronczak, M.; Leighton, J.; Ordeniza, E.; Ritchie, B.; Valado, N.; Walsh, N.; Antoney, J. P.; Wang, C.; Scott, C.; Speight, R.; Vickers, C.; Peng, B.

10.1101/2024.03.26.586389 — synthetic biology — Posted on 2024-03-27

777 Single-Molecule Orientation Imaging Reveals the Nano-Architecture of Amyloid Fibrils Undergoing Growth and Decay

Sun, B.; Ding, T.; Zhou, W.; Porter, T. S.; Lew, M. D.

10.1101/2024.03.24.586510 — biophysics — Posted on 2024-03-27

778 Exploring structural diversity across the protein universe with The Encyclopedia of Domains

Lau, A. M. C.; Bordin, N.; Kandathil, S. M.; Sillitoe, I.; Waman, V. P.; Wells, J.; Orengo, C.; Jones, D. T.

10.1101/2024.03.18.585509 — bioinformatics — Posted on 2024-03-27

779 hictk: blazing fast toolkit to work with .hic and .cool files

Rossini, R.; Paulsen, J.

10.1101/2023.11.26.568707 — bioinformatics — Posted on 2024-03-27

780 How do Large Language Models understand Genes and Cells

Fang, C.; Wang, Y.; Song, Y.; Long, Q.; Lu, W.; Chen, L.; Wang, P.; Feng, G.; Zhou, Y.; Li, X.

10.1101/2024.03.23.586383 — bioinformatics — Posted on 2024-03-27

781 CCQM-P199b: Interlaboratory comparability study of SARS-CoV-2 RNA copy number quantification

Devonshire, A. S.; Busby, E. J.; Jones, G. M.; O'Sullivan, D. M.; Fernandez-Gonzalez, A.; Hernandez-Hernandez, L.; Dai, X.; Dong, L.; Niu, C.; Xie, J.; Wang, X.; Qiao, X.; Fang, X.; Morris, C.; Almond, N.; Cleveland, M. H.; Vallone, P. M.; Castro Galvan, E.; Perez Urquiza, M.; Guadalupe Herrera Lopez, M.; Khan, A. S.; Fuentes, S. M.; Emerson Leguizamon, J.; Luis Davila Gonzalez, S.; Felipe Leon Torres, A.; Folgueras-Flatschart, A. V.; Neves de Medeiros, M.; Marcos Saraiva, A.; Becht Flatschart, R.; Divieto, C.; Pegoraro, M.; Zucco, M.; Revel, L.; Mazzara, M.; Corbisier, P.; Buttinger, G.; Yang

10.1101/2024.03.27.584106 — molecular biology — Posted on 2024-03-27

782 In-silico docking platform with serine protease inhibitor (SERPIN) structures identifies host cysteine protease targets with significance for SARS-CoV-2

Rodriguez Galvan, J. J.; de Vries, M.; Belblidia, S.; Fisher, A.; Prescott, R. A.; Crosse, K. M.; Mangel, W. F.; Duerr, R.; Dittmann, M.

10.1101/2022.11.18.517133 — microbiology — Posted on 2024-03-27

783 Virological characteristics of SARS-CoV-2 Omicron BA.5.2.48

Wang, W.; Jin, Q.; Liu, R.; Zeng, W.; Zhu, P.; Li, T.; Wang, T.; Xiang, H.; Zhang, H.; Chen, Q.; Gao, Y.; Lai, Y.; Yan, F.; Xia, X.; Li, J.; Wang, X.; Gao, Y.

10.1101/2024.03.26.586802 — microbiology — Posted on 2024-03-27

784 TCR transgenic clone selection guided by immune receptor analysis and single cell RNA expression of polyclonal responders

Debeuf, N.; Lameire, S.; Vanheerswynghels, M.; Deckers, J.; De Wolf, C.; Toussaint, W.; Verbeke, R.; Verstaen, K.; Hammad, H.; Vanhee, S.; Lambrecht, B. N.

10.1101/2024.03.27.586931 — immunology — Posted on 2024-03-27

785 Intercellular Signaling Pathways as Therapeutic Targets for Vascular Dementia Repair

Tian, M.; Kawaguchi, R.; Shen, Y.; Machnicki, M.; Villegas, N. G.; Cooper, D. R.; Montgomery, N.; Haring, J.; Lan, R.; Yuan, A. H.; Williams, C. K.; Magaki, S.; Vinters, H. V.; Zhang, Y.; De Biase, L. M.; Silva, A. J.; Carmichael, S. T.

10.1101/2024.03.24.585301 — neuroscience — Posted on 2024-03-27

786 The Effects of Acute Coordinative vs. Acute Endurance Exercise on the Cortisol Concentration

Budde, H.; Wegner, M.; Ahrens, C.; Velasques, B.; Ribeiro, P.; Machado, S.; Mueller-Alcazar, A.

10.1101/2024.03.25.586687 — physiology — Posted on 2024-03-27

787 Approach to standardized material characterization of the human lumbopelvic system - Testing and evaluation

Gebhardt, M.; Kurz, S.; Grundmann, F.; Klink, T.; Slowik, V.; Heyde, C.-E.; Steinke, H.

10.1101/2024.03.24.586492 — biophysics — Posted on 2024-03-27

788 Conditions for the co-existence of promoter and gene-body condensates

Changiarath, A.; Michels, J.; Rodriguez, R. H.; Hanson, S. M.; Schmid, F.; Padeken, J.; Stelzl, L. S.

10.1101/2024.03.16.585180 — biophysics — Posted on 2024-03-27

789 Crosslinking by ZapD drives the assembly of short FtsZ filaments into toroidal structures in solution

Merino-Salomon, A.; Schneider, J.; Babl, L.; Krohn, J.-H.; Sobrinos-Sanguino, M.; Schäfer, T.; Luque-Ortega, J. R.; Alfonso, C.; Jimenez, M.; Jasnin, M.; Schwille, P.; Rivas, G.

10.1101/2023.01.12.523557 — biochemistry — Posted on 2024-03-27

790 Phosphorylation of Aly3 C-terminus impedes aberrant endocytosis of S. pombe hexose transporter Ght5

Toyoda, Y.; Masuda, F.; Saitoh, S.

10.1101/2024.03.24.586504 — cell biology — Posted on 2024-03-27

791 A prefrontal motor circuit initiates persistent movement

Wang, Y.; Sun, Q.-Q.

10.1101/2023.07.11.548619 — neuroscience — Posted on 2024-03-27

792 Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction

Bayer, H.; Hassell, J. E.; Oleksiak, C. R.; Garcia, G. M.; Vaughan, H.; Juliano, V. A. L.; Maren, S.

10.1101/2024.03.23.586410 — neuroscience — Posted on 2024-03-27

793 Biophysical neural adaptation mechanisms enable artificial neural networks to capture dynamic retinal computation

Idrees, S.; Manookin, M. B.; Rieke, F.; Field, G. D.; Zylberberg, J.

10.1101/2023.06.20.545728 — neuroscience — Posted on 2024-03-27

794 Pushing the boundaries of MEG based on optically pumped magnetometers towards early human life

Corvilain, P.; Wens, V.; Bourguignon, M.; Capparini, C.; Fourdin, L.; Ferez, M.; Feys, O.; De Tiege, X.; Bertels, J.

10.1101/2023.10.28.564455 — neuroscience — Posted on 2024-03-27

795 Human HPSE2 gene transfer ameliorates bladder pathophysiology in a mutant mouse model of urofacial syndrome.

Lopes, F. M.; Grenier, C.; Jarvis, B. W.; Al Mahdy, S.; Lene-Mckay, A.; Gurney, A. M.; Newman, W. G.; Waddington, S. N.; Woolf, A. S.; Roberts, N. A.

10.1101/2023.07.03.547034 — neuroscience — Posted on 2024-03-27

796 Topographical polarity reveals continuous EEG microstate transitions and electric field direction in healthy aging

Kashihara, S.; Asai, T.; Imamizu, H.

10.1101/2024.03.24.586427 — neuroscience — Posted on 2024-03-27

797 Perception - action dissociations depend on factors that affect multisensory processing

Uccelli, S.; Bruno, N.

10.1101/2024.03.24.586486 — neuroscience — Posted on 2024-03-27

798 Aging-associated weakening of the action potential in fast-spiking interneurons in the human neocortex

Szegedi, V.; Tiszlavicz, A.; Furdan, S.; Douida, A.; Bakos, E.; Barzo, P.; Tamas, G.; Szucs, A.; Lamsa, K.

10.1101/2024.03.24.586453 — neuroscience — Posted on 2024-03-27

799 PKHD1L1 is required for stereocilia bundle maintenance, durable hearing function and resilience to noise exposure.

Strelkova, O. S.; Osgood, R. T.; Tian, C. J.; Zhang, X.; Hale, E.; De-la-Torre, P.; Hathaway, D. M.; Indzhykulian, A. A.

10.1101/2024.02.29.582786 — neuroscience — Posted on 2024-03-27

800 ER-anchored protein sorting controls the fate of two proteasome activators for intracellular organelle communication during proteotoxic stress

Langin, G.; Raffeiner, M.; Biermann, D.; Franz-Wachtel, M.; Spinti, D.; Börnke, F.; Macek, B.; Üstün, S.

10.1101/2023.12.11.571118 — plant biology — Posted on 2024-03-27

801 Pure Nano Genesis: Pioneering Universal Aqueous Nanostrategies from Pure Molecules to Revolutionise Diverse Applications

Zhao, W.; Li, Q.; He, P.; Li, C.; Aryal, M.; Fabiilli, M.; Xiao, H.

10.1101/2024.03.24.586367 — pharmacology and toxicology — Posted on 2024-03-27

802 Role of 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 in Maintaining Redox Homeostasis and DNA Repair in Non-Small Cell Lung Cancers Under EGFR-Targeting Therapy

Lypova, N.; Dougherty, S. M.; Clem, B. F.; Feng, J.; Yin, X.; Zhang, X.; Li, X.; Chesney, J. A.; Imbert-Fernandez, Y.

10.1101/2024.03.25.586703 — cancer biology — Posted on 2024-03-27

803 Enhanced extracellular matrix remodeling due to embedded spheroid fluidization

Zhang, T.; Ameen, S.; Ghosh, S.; Kim, K.; Thanh, M.; Patteson, A. E.; Wu, M.; Schwarz, J. M.

10.1101/2024.03.25.586590 — biophysics — Posted on 2024-03-27

804 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening

Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.

10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-27

805 Multiple Alzheimer's disease progression pathways inferred from transcriptome data of the dorsolateral prefrontal cortex

Honda, K.; Awazu, A.

10.1101/2024.03.24.586514 — bioinformatics — Posted on 2024-03-27

806 Application of chimeric antigens to paper-based diagnostics for detection of West Nile virus infections of Crocodylus porosus: a novel animal test case

Johnston, R. A.; Habarugira, G.; Harrison, J. J.; Isberg, S. R.; Moran, J.; Morgan, M.; Davis, S. S.; Melville, L. F.; Howard, C. B.; Henry, C. S.; Macdonald, J.; Bielefeldt-Ohmann, H. A.; Hall, R. A.; Hobson-Peters, J.

10.1101/2024.03.24.586480 — biochemistry — Posted on 2024-03-27

807 Multifaceted roles of cohesin in regulating transcriptional loops

Kim, M.; Wang, P.; Clow, P.; Chien, I.; Wang, X.; Peng, J.; Chai, H.; Liu, X.; Lee, B.; Ngan, C. Y.; Yue, F.; Milenkovic, O.; Chuang, J. H.; Wei, C.-L.; Casellas, R.; Cheng, A.; Ruan, Y.

10.1101/2024.03.25.586715 — genomics — Posted on 2024-03-27

808 Landscape of microRNA and target expression variation and covariation in single mouse embryonic stem cells

Tarbier, M.; Mackowiak, S. D.; Sekar, V.; Bonath, F.; Yapar, E.; Fromm, B.; Faridani, O. R.; Biryukova, I.; Friedländer, M. R.

10.1101/2024.03.24.586475 — genomics — Posted on 2024-03-27

809 Mutation of GmDMP genes triggers haploid induction in soybean

Zhong, Y.; Yang, M.; Cheng, D.; Liu, J.; Han, Q.; Liu, C.; Qi, X.; Yan, T.; Teng, L.; Xv, C.; Hou, J.; Sun, L.; Liu, C.; Chen, Q.; Chen, S.

10.1101/2024.03.24.585499 — genetics — Posted on 2024-03-27

810 Single-character insertion-deletion model preserves long indels in ancestral sequence reconstruction

Jowkar, G.; Pecerska, J.; Gil, M.; Anisimova, M.

10.1101/2024.03.09.584071 — evolutionary biology — Posted on 2024-03-27

811 EVOLUTIONARY CO-OPTION OF AN ANCESTRAL CLOACAL REGULATORY LANDSCAPE DURING THE EMERGENCE OF DIGITS AND GENITALS

Hintermann, A.; Bolt, C. C.; Hawkins, M. B.; Valentin, G.; Lopez-Delisle, L.; Gitto, S.; Gomez, P. B.; Mascrez, B.; Mansour, T. A.; Nakamura, T.; Harris, M. P.; Shubin, N. H.; Duboule, D.

10.1101/2024.03.24.586442 — evolutionary biology — Posted on 2024-03-27

812 Causality in the natural selection of the population ecological life histories of birds

Witting, L.

10.1101/2024.03.23.586398 — evolutionary biology — Posted on 2024-03-27

813 : A tool for modelling ecosystem resilience

Klimes, A.; Chipperfield, J. D.; Topper, J. P.; Macias-Fauria, M.; Spiegel, M.; Vandvik, V.; Velle, L. G.; Seddon, A. W. R.

10.1101/2024.03.23.586419 — ecology — Posted on 2024-03-27

814 Discordant changes in foliar and reproductive phenology of tropical dry-forest trees under increasing temperature and decreasing wet-season rainfall

Lai, H. R.; Hill, T.; Stivanello, S.; Chapman, H. M.

10.1101/2024.03.24.585819 — ecology — Posted on 2024-03-27

815 Neuronal activation affects the organization and protein composition of the nuclear speckles

Szczepankiewicz, A. A.; Parobczak, K.; Zareba-Koziol, M.; Ruszczycki, B.; Bijata, M.; Trzaskoma, P.; Hajnowski, G.; Holm-Kaczmarek, D.; Wlodarczyk, J.; Wilczynski, G. M.; Redowicz, M. J.; Magalska, A.

10.1101/2024.03.25.586583 — cell biology — Posted on 2024-03-27

816 mTOR activation induces endolysosomal remodeling and unconventional secretion of IL-32 via exosomes in inflammatory reactive astrocytes

Leng, K.; Rooney, B.; McCarthy, F.; Xia, W.; Rose, I. V. L.; Bax, S.; Chin, M. Y.; Fathi, S.; Herrington, K. A.; Leonetti, M.; Kao, A. W.; Fancy, S. P. J.; Elias, J. E.; Kampmann, M.

10.1101/2021.09.11.459904 — cell biology — Posted on 2024-03-27

817 Adaptive chunking improves effective working memory capacity in a prefrontal cortex and basal ganglia circuit

Soni, A.; Frank, M. J.

10.1101/2024.03.24.586455 — neuroscience — Posted on 2024-03-27

818 Adult expression of the cell adhesion protein Fasciclin 3 is required for the maintenance of adult olfactory interneurons

Vaikakkara Chithran, A.; Allan, D.; O'Connor, T.

10.1101/2024.03.24.586496 — neuroscience — Posted on 2024-03-27

819 Enteric glutamatergic interneurons regulate intestinal motility

Hamnett, R.; Bendrick, J. L.; Robertson, K.; Zhao, E. T.; Kaltschmidt, J. A.

10.1101/2024.03.24.586153 — neuroscience — Posted on 2024-03-27

820 No Evidence of Altered Language Laterality in People Who Stutter across Different Brain Imaging Studies of Speech and Language

Demirel, B.; Chesters, J.; Connally, E.; Gough, P.; Ward, D.; Howell, P.; Watkins, K. E.

10.1101/2024.03.23.586392 — neuroscience — Posted on 2024-03-27

821 Ageing impacts basic auditory and timing processing

Criscuolo, A.; Schwartze, M.; Bonetti, L.; Kotz, S. A.

10.1101/2024.03.24.586049 — neuroscience — Posted on 2024-03-27

822 Mapping Serotonergic Dynamics using Drug-Modulated Molecular Connectivity

Ionescu, T. M.; Amend, M.; Hafiz, R.; Maurer, A.; Biswal, B. B.; Wehrl, H. F.; Herfert, K.

10.1101/2024.02.08.579462 — neuroscience — Posted on 2024-03-27

823 Neural signatures of human psychological resilience driven by acute stress

Watanabe, N.; Yoshida, S.; Keerativittayayut, R.; Takeda, M.

10.1101/2024.03.24.586503 — neuroscience — Posted on 2024-03-27

824 The regulatory architecture of the primed pluripotent cell state

Li, B. I.; Alvarez, M. J.; Zhao, H.; Chirathivat, N.; Califano, A.; Shen, M. M.

10.1101/2024.03.25.586622 — systems biology — Posted on 2024-03-27

825 Nuclear actin and DNA replication stress regulate the recruitment of human telomerase to telomeres

Harman, A.; Kartawinata, M.; Maroun, N. M.; Nguyen, D. R.; Hughes, W. E.; Winardi, K.; Cesare, A. J.; Lamm, N.; Bryan, T. M.

10.1101/2024.03.25.586711 — cancer biology — Posted on 2024-03-27

826 Emerging role of oncogenic β-catenin in exosome biogenesis as a driver of immune escape in hepatocellular carcinoma

Dantzer, C.; Vache, J.; Brunel, A.; Mahouche, I.; Raymond, A.-A.; Dupuy, J.-W.; Petrel, M.; Bioulac-Sage, P.; Perrais, D.; Dugot-Senant, N.; Verdier-Sage, M.; Bessette, B.; Billottet, C.; Moreau, V.

10.1101/2023.10.24.563805 — cancer biology — Posted on 2024-03-27

827 Augmented Doubly Robust Post-Imputation Inference for Proteomic data

Moon, H.; Du, J.-H.; Lei, J.; Roeder, K.

10.1101/2024.03.23.586387 — bioinformatics — Posted on 2024-03-27

828 Multi-drug interaction target-controlled infusion fromsimultaneous optimization of pharmacometric models

Vazquez, P. M.; Abad-Torrent, A.

10.1101/2024.03.24.586464 — bioengineering — Posted on 2024-03-27

829 Enhancing amino acid productivity and profile in black soldier fly larvae through NAT transporter suppression in the excretion system

Liu, C.-M.; Uehara, T.; Shimoda, M.

10.1101/2024.03.24.586506 — bioengineering — Posted on 2024-03-27

830 Multi-omics characterization of highly enriched human plasma extracellular vesicles.

Su, H.; Fowler, C.; Masters, C. L.; Barnham, K. J.; Reid, G. E.; Vella, L. J.

10.1101/2024.03.25.586695 — biochemistry — Posted on 2024-03-27

831 Predicting nonlinear genetic relationships between traits in multi-trait evaluations by using a GBLUP-assisted Deep Learning model

Shokor, F.; Croiseau, P.; Gangloff, H.; Saintilan, R.; Tribout, T.; Mary-Huard, T.; C.D Cuyabano, B.

10.1101/2024.03.23.585208 — genomics — Posted on 2024-03-27

832 Complete telomere-to-telomere assemblies of two sorghum genomes to guide biological discovery

Wei, C.; Gao, L.; Xiao, R.; Wang, Y.; Chen, B.; Zou, W.; Li, J.; Emma, M.; David, J.; Tao, Y.

10.1101/2024.03.24.586445 — genomics — Posted on 2024-03-27

833 A structured coalescent model reveals deep ancestral structure shared by all modern humans

Cousins, T.; Scally, A.; Durbin, R.

10.1101/2024.03.24.586479 — genetics — Posted on 2024-03-27

834 Mutation bias alters the distribution of fitness effects of mutations

Sane, M.; Parveen, S.; Agashe, D.

10.1101/2024.03.24.586369 — evolutionary biology — Posted on 2024-03-27

835 Cause and effect in the natural selection of the population ecological life histories of mammals

Witting, L.

10.1101/2024.03.23.586396 — evolutionary biology — Posted on 2024-03-27

836 Analysis Pipeline to Quantify Uterine Gland Structural Variations

Khan, S.; Alessio, A.; Arora, R.

10.1101/2024.03.24.586502 — developmental biology — Posted on 2024-03-27

837 Unveiling the double-edged sword: SOD1 trimers possess tissue-selective toxicity and bind septin-7 in motor neuron-like cells

Choi, E. S.; Hnath, B. L.; Sha, C. M.; Dokholyan, N. V.

10.1101/2024.03.22.586186 — neuroscience — Posted on 2024-03-27

838 Decomposed frontal corticostriatal ensemble activity changes across trials, revealing distinct features relevant to outcome-based decision making

Handa, T.; Fukai, T.; Kurikawa, T.

10.1101/2024.03.23.586395 — neuroscience — Posted on 2024-03-27

839 Nutrient Sensing Receptor GPRC6A Regulates mTORC1 Signaling and Tau Biology

Ma, C.; Campbell, K.; Kovalenko, A.; Sandusky-Beltran, L. A.; Liang, H.; Hunt, J. B.; Calahatian, J.; Kallupurackal, M.; Pandey, S.; Vasisht, M.; Walter, M.; Quadri, Z.; Michalski, C.; Fahnestock, M.; Papangelis, A.; Pedersen, D. S.; Ulven, T.; Nash, K.; Selenica, M.-L. B.; Morgan, D.; Bickford, P. C.; Lee, D. C.

10.1101/2024.03.24.586459 — neuroscience — Posted on 2024-03-27

840 Midbrain encodes sound detection behavior without auditory cortex

Lee, T.-Y.; Weissenberger, Y.; King, A. J.; Dahmen, J. C.

10.1101/2023.06.07.544013 — neuroscience — Posted on 2024-03-27

841 Noise schemas aid hearing in noise

Hicks, J. M.; McDermott, J. H.

10.1101/2024.03.24.586482 — neuroscience — Posted on 2024-03-27

842 Heterogeneity in slow synaptic transmission diversifies Purkinje cell timing

Thomas, R. E.; Mudlaff, F.; Schweers, K.; Farmer, W. T.; Suvrathan, A.

10.1101/2024.03.24.585592 — neuroscience — Posted on 2024-03-27

843 Testing Anopheles larvae and adults using standard bioassays reveals susceptibility to chlorfenapyr (pyrrole) while highlighting variability between species

Bouaka, C.; Ambadiang, M.; Ashu, F.; Fouet, C.; Kamdem, C.

10.1101/2024.03.24.586483 — zoology — Posted on 2024-03-27

844 Sexual dimorphism in the dorsal spot number and yellow surface in fire salamanders Salamandra salamandra ssp terrestris Linnaeus, 1758 (Caudata: Salamandridae)

Bozon, M.; Marteau, B.

10.1101/2024.03.25.586466 — zoology — Posted on 2024-03-27

845 Fat body lipogenic capacity in honey bee workers is affected by age, social role, and dietary protein

Scofield, S.; Amdam, G. V.

10.1101/2024.03.24.586478 — physiology — Posted on 2024-03-27

846 Root surface treatment for delayed replantation of avulsed teeth in animal models: a systematic review

Huaman, S. D.; Vilela, M. M.; Nelson-Filho, P.; De-Rossi, A.; Queiroz, A. M.; Paula-Silva, F. W. G.

10.1101/2024.03.24.586399 — pharmacology and toxicology — Posted on 2024-03-27

847 Patient-derived response estimates from zero-passage organoids of luminal breast cancer

Przanowska, R.; Labban, N.; Przanowski, P.; Hawes, R.; Atkins, K.; Showalter, S.; Janes, K.

10.1101/2024.03.24.586432 — cancer biology — Posted on 2024-03-27

848 Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective light-sheet microscopy

Dunsing-Eichenauer, V.; Hummert, J.; Chardes, C.; Schönau, T.; Guignard, L.; Galland, R.; Grenci, G.; Tillmann, M.; Koberling, F.; Nock, C.; Sibarita, J.-B.; Viasnoff, V.; Antolovic, I. M.; Erdmann, R.; Lenne, P.-F.

10.1101/2024.03.24.586451 — biophysics — Posted on 2024-03-27

849 A portable electrochemical DNA sensor for sensitive and tunable detection of piconewton-scale cellular forces

Tabrizi, M. A.; Ali, A. A.; Singuru, M. M. R.; Mi, L.; Bhattacharyya, P.; You, M.

10.1101/2024.03.24.586508 — biophysics — Posted on 2024-03-27

850 BetaAlign: a deep learning approach for multiple sequence alignment

Dotan, E.; Wygoda, E.; Ecker, N.; Alburquerque, M.; Avram, O.; Belinkov, Y.; Pupko, T.

10.1101/2024.03.24.586462 — bioinformatics — Posted on 2024-03-27

851 Cerebrovascular reactivity mapping using breath-hold BOLD-fMRI: comparison of signal models combined with voxelwise lag optimization

Domingos, C.; Esteves, I.; Fouto, A. R.; Ruiz-Tagle, A.; Caetano, G.; Figueiredo, P.

10.1101/2024.03.22.586319 — bioengineering — Posted on 2024-03-27

852 Evaluation of Treatment of Methicillin-Resistant Staphylococcus aureus Biofilms with Intermittent Electrochemically-Generated H2O2 or HOCl

Anoy, M. M. I.; Kim, W.-J.; Gelston, S.; Fleming, D.; Patel, R.; Beyenal, H.

10.1101/2024.03.22.586337 — bioengineering — Posted on 2024-03-27

853 DUAL ACTION ELECTROCHEMICAL BANDAGE OPERATED by a PROGRAMMABLE MULTIMODAL WEARABLE POTENTIOSTAT

Bozyel, I.; Fleming, D.; Kim, W.-J.; Rosern, P. F.; Gelston, S.; Ozdemir, D.; Ay, S. U.; Patel, R.; Beyenal, H.

10.1101/2024.03.22.586346 — bioengineering — Posted on 2024-03-27

854 Does Vibrotactile Stimulation of the Auricular Vagus Nerve Enhance Working Memory? A Behavioral and Physiological Investigation

Tan, G.; Adams, J.; Donovan, K.; Demarest, P.; Willie, J. T.; Brunner, P.; Leuthardt, E.

10.1101/2024.03.24.586365 — bioengineering — Posted on 2024-03-27

855 Five millennia of mitochondrial introgression in Atlantic bluefin tuna identified using ancient DNA

Eriksen, E. F.; Andrews, A. J.; Nielsen, S. V.; Persson, P.; Malca, E.; Onar, V.; Aniceti, V.; Piques, G.; Piattoni, F.; Fontani, F.; Wiech, M.; Ferter, K.; Kersten, O.; Ferrari, G.; Cariani, A.; Tinti, F.; Cilli, E.; Atmore, L. M.; Star, B.

10.1101/2024.03.24.586294 — evolutionary biology — Posted on 2024-03-27

856 Thermal tolerance of mosquito eggs is associated with urban adaptation and human interactions

Chakraborty, S.; Zigmond, E.; Shah, S.; Sylla, M.; Akorli, J.; Otoo, S.; Rose, N. H.; McBride, C. S.; Armbruster, P. A.; Benoit, J. B.

10.1101/2024.03.22.586322 — ecology — Posted on 2024-03-27

857 The repercussions of timing in the invasion of synthetic bacterial communities

Dooley, K. D.; Bergelson, J.

10.1101/2024.03.24.586461 — ecology — Posted on 2024-03-27

858 Non-mechanical disruption of Bacillus subtilis spores allows sensitive and deep characterization of the minimal proteome for resuming a cellular lifestyle.

Huang, Y.; de Koster, A.; Tu, Z.; Gao, X.; Roseboom, W.; Brul, S.; Setlow, P.; Kramer, G.

10.1101/2024.03.08.584050 — microbiology — Posted on 2024-03-27

859 New high-throughput screening assays for nitrification inhibitors identify an oxazolidine-thione as biological nitrification inhibitor

Beeckman, F.; Drozdzecki, A.; De Knijf, A.; Audenaert, D.; Beeckman, T.; Motte, H.

10.1101/2024.03.27.586932 — microbiology — Posted on 2024-03-27

860 Coordinated regulation of osmotic imbalance by c-di-AMP shapes beta-lactam tolerance in Group B Streptococcus

Brissac, T.; Guyonnet, C.; Sadouni, A.; Hernandez Montoya, A.; Jacquemet, E.; Legendre, R.; Sismeiro, O.; Trieu-Cuot, P.; Lanotte, P.; Tazi, A.; Firon, A.

10.1101/2024.03.27.586946 — microbiology — Posted on 2024-03-27

861 3D live imaging and phenotyping of the subcellular cytotoxicity in cancer immunotherapy using event-triggered Bessel oblique plane microscopy

Wang, Z.; Wang, J.; Zhao, Y.; Jin, J.; Chen, L.; Fei, P.

10.1101/2024.03.23.586380 — immunology — Posted on 2024-03-27

862 Primate V2 Receptive Fields Derived from Anatomically Identified Large-Scale V1 Inputs

Hassanpour, M. S.; Merlin, S.; Frederick Federer, F.; Zaidi, Q.; Angelucci, A.

10.1101/2024.03.22.586002 — neuroscience — Posted on 2024-03-27

863 Compromised retinoic acid receptor beta (RARb) accelerates the onset of motor, cellular and molecular abnormalities in mouse model of Huntington's disease.

Zinter, N.; Ye, T.; FRAULOB, V.; PLASSARD, D.; Krezel, W.

10.1101/2024.03.23.586058 — neuroscience — Posted on 2024-03-27

864 Theta-Gamma Phase-Amplitude Coupling Supports Working Memory Performance in the Human Hippocampus

Salimpour, Y.; Anderson, W.

10.1101/2024.03.24.586454 — neuroscience — Posted on 2024-03-27

865 Museomics of Carabus giant ground beetles evidences an Oligocene origin and in situ Alpine diversification

PAULI, M. T.; GAUTHIER, J.; LABEDAN, M.; BLANC, M.; BILAT, J.; TOUSSAINT, E. F. A.

10.1101/2024.03.21.586057 — zoology — Posted on 2024-03-27

866 MOS4-Associated Complex subunits 3A and 3B modulate FLM splicing to repress photoperiod-dependent floral transition

Huang, Y.-W.; Tseng, C.-Y.; Tu, Y.-T.; Hsieh, H.-Y.; Wang, Y.-S.; Chen, Y.-Z.; Ly, Y.-T.; Tu, S.-L.; Lee, C.-M.

10.1101/2024.03.26.586198 — plant biology — Posted on 2024-03-27

867 Pannexin 1 Channels Control Cardiomyocyte Metabolism and Neutrophil Recruitment During Non-Ischemic Heart Failure

Pavelec, C. M.; Young, A.; Luviano, H. L.; Orrell, E. E.; Szagdaj, A.; Poudel, N.; Wolpe, A. G.; Thomas, S. H.; Yeudall, S.; Upchurch, C.; Okusa, M. D.; Isakson, B. E.; Wolf, M. J.; Leitinger, N.

10.1101/2023.12.29.573679 — physiology — Posted on 2024-03-27

868 Self-perceived middle-distance race pace is faster in Advanced Footwear Technology spikes

Bertschy, M.; Rodrigo Carranza, V.; Wilkie, E. W. C.; Healey, L. A.; Noble, J.; Albert, W. J.; Hoogkamer, W.

10.1101/2023.10.25.564056 — physiology — Posted on 2024-03-27

869 ChemPrint: An AI-Driven Framework for Enhanced Drug Discovery

Umansky, T.; Ramesh, N.; Woods, V.; Russell, S. M.; Smith, D. M.; Haders, D.

10.1101/2024.03.22.586314 — bioinformatics — Posted on 2024-03-27

870 Taxonize-gb: A tool for filtering GenBank non-redundant databases based on taxonomy

Sarhan, M. S.; Filosi, M.; Maixner, F.; Fuchsberger, C.

10.1101/2024.03.22.586347 — bioinformatics — Posted on 2024-03-27

871 mm2-gb: GPU Accelerated Minimap2 for Long Read DNA Mapping

Dong, J.; Liu, X.; Sadasivan, H.; Sitaraman, S.; Narayanasamy, S.

10.1101/2024.03.23.586366 — genomics — Posted on 2024-03-27

872 Acute multi-level response to defective de novo chromatin assembly in S-phase

Dreyer, J.; Ricci, G.; van den Berg, J.; Bhardwaj, V.; Funk, J.; Armstrong, C.; van Batenburg, V.; Sine, C.; Vaninsberghe, M. A.; Marsman, R.; Mandemaker, I. K.; di Sanzo, S.; Costantini, J.; Manzo, S.; Biran, A.; Burny, C.; Voelker-Albert, M.; Groth, A.; Spencer, S. L.; van Oudenaarden, A.; Mattiroli, F.

10.1101/2024.03.22.586291 — cell biology — Posted on 2024-03-27

873 A panel of phenotypically and genotypically diverse bioluminescent: fluorescent Trypanosoma cruzi strains as a resource for Chagas disease research

Olmo, F.; Jayawardhana, S.; Khan, A. A.; Langston, H. C.; Francisco, A. F.; Atherton, R. A.; Ward, A. I.; Taylor, M. C.; Kelly, J. M.; Lewis, M. D.

10.1101/2024.03.27.586912 — microbiology — Posted on 2024-03-27

874 Multi-omics analysis reveals regime shifts in the gastrointestinal ecosystem in chickens following anticoccidial vaccination and Eimeria tenella challenge

Liu, P.-Y.; Liaw, J.; Soutter, F.; Ortiz, J. J.; Tomley, F. M.; Werling, D.; Gundogdu, O.; Blake, D. P.; Xia, D.

10.1101/2024.03.27.586915 — microbiology — Posted on 2024-03-27

875 Bacterial profiles of the oral, vaginal, and rectal mucosa and colostrum of periparturient sows

Piirainen, V.; Konig, E.; Husso, A.; Heinonen, M.; Iivanainen, A.; Pessa-Morikawa, T.; Niku, M.

10.1101/2024.03.27.586787 — microbiology — Posted on 2024-03-27

876 Palmitoylation regulates norepinephrine transporter trafficking and expression and is potentially involved in the pathogenesis of postural orthostatic tachycardia syndrome

Brown, C. R.; Foster, J. D.

10.1101/2024.03.22.586171 — neuroscience — Posted on 2024-03-27

877 Distinct roles of medial prefrontal cortex subregions in the consolidation and recall of remote spatial memories

Centofante, E.; Santoboni, M.; Mombelli, E. L.; Rinaldi, A.; Mele, A.

10.1101/2024.03.22.586327 — neuroscience — Posted on 2024-03-27

878 Mutation of negative regulatory gene CEHC1 encoding an FBXO3 protein results in normoxic expression of HYDA genes in Chlamydomonas reinhardtii

Sun, X.; LaVoie, M.; Lefebvre, P.; Gallaher, S. D.; Glaesener, A. G.; Strenkert, D.; Mehta, R.; Merchant, S. S.; Silflow, C. D.

10.1101/2024.03.22.586359 — plant biology — Posted on 2024-03-27

879 Hyperspectral imaging for chloroplast movement detection

Hermanowicz, P.; Labuz, J. M.

10.1101/2024.03.26.586650 — plant biology — Posted on 2024-03-27

880 Dramatic Changes in Mitochondrial Subcellular Location and Morphology Accompany Activation of the CO2 Concentrating Mechanism

Findinier, J.; Joubert, L.-M.; Schmid, M. F.; Malkovskiy, A.; Chiu, W.; Burlacot, A.; Grossman, A. R.

10.1101/2024.03.25.586705 — plant biology — Posted on 2024-03-27

881 Chara canescens part I: Oospore differentiation of parthenogenic and dioecious strains and salt-dependent oospore sizes

Holzhausen, A.; Romanov, R.; Schubert, H.

10.1101/2024.03.26.586877 — plant biology — Posted on 2024-03-27

882 Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases

Rempfer, C.; Hoernstein, S. N. W.; van Gessel, N.; Graf, A. W.; Spiegelhalder, R. P.; Bertolini, A.; Bohlender, L. L.; Parsons, J.; Decker, E. L.; Reski, R.

10.1101/2024.03.26.586753 — plant biology — Posted on 2024-03-27

883 Demographic and genetic impacts of powdery mildew in a young oak cohort

Barres, B.; Dutech, C.; Saint-Jean, G.; Bodenes, C.; Burban, C.; Fievet, V.; Lepoittevin, C.; Garnier-Gere, P.; Desprez-Loustau, M.-L.

10.1101/2023.06.22.546164 — plant biology — Posted on 2024-03-27

884 Comparative Analysis of DNA Structural Parameters and the Corresponding Computational Tools to Differentiate Regulatory DNA Motifs and Promoters

Manivelan, V.; Kavyashree, B.; Sadanandan, B.; Vaidya, S.; Acharya, K. K.

10.1101/2024.03.26.584893 — bioinformatics — Posted on 2024-03-27

885 Kilohertz volumetric imaging of in-vivo dynamics using squeezed light field microscopy

Wang, Z.; Zhao, R.; Wagenaar, D. A.; Kang, W.; Lee, C.; Schmidt, W.; Pammar, A.; Zhu, E.; Wong, G. C. L.; Liang, R.; Hsiai, T.; Gao, L.

10.1101/2024.03.23.586416 — bioengineering — Posted on 2024-03-27

886 STING-Activating Polymer-Drug Conjugates for Cancer Immunotherapy

Sheehy, T. L.; Kwiatkowski, A. J.; Arora, K.; Kimmel, B. R.; Schulman, J. A.; Gibson-Corley, K.; Wilson, J. T.

10.1101/2024.03.23.585817 — bioengineering — Posted on 2024-03-27

887 Elucidating the sustainability of 700 years of Inuvialuit beluga whale hunting in the Mackenzie River Delta, Northwest Territories, Canada

Skovrind, M.; Louis, M.; Ferguson, S.; Glazov, D. M.; Litovka, D. I.; Loseto, L. L.; Meschersky, I. G.; MIller, M. M.; Postma, L. D.; Rozhnov, V. V.; Scott, M.; Westbury, M. V.; Szpak, P.; Friesen, T. M.; Lorenzen, E. D.

10.1101/2024.03.22.586343 — genomics — Posted on 2024-03-27

888 Single-cell epigenomic dysregulation of Systemic Sclerosis fibroblasts via CREB1/EGR1 axis in self-assembled human skin equivalents

Abel, T. R.; Kosarek, N. N.; Parvizi, R.; Jarnagin, H. C.; Torres, G. M.; Bhandari, R.; Huang, M.; Toledo, D.; Smith, A.; Popovich, D.; Mariani, M. P.; Yang, H.; Wood, T. A.; Garlick, J.; Pioli, P. A.; Whitfield, M. L.

10.1101/2024.03.22.586316 — genomics — Posted on 2024-03-27

889 Mutational scanning of CRX classifies clinical variants and reveals biochemical properties of the transcriptional effector domain

Shepherdson, J. L.; Granas, D. M.; Li, J.; Shariff, Z.; Plassmeyer, S. P.; Holehouse, A. S.; White, M. A.; Cohen, B. A.

10.1101/2024.03.21.585809 — genomics — Posted on 2024-03-27

890 A basic framework governing splice-site choice in eukaryotes

Dent, C. I.; Prodic, S.; Balakrishnan, A.; Georges, J.; Chhabra, A.; Mukherjee, S.; Coutts, J. P.; Gitonobel, M.; Sarwade, R. D.; Rosenbluh, J.; D'Amato, M.; Das, P. P.; Guo, Y.; Fournier-Level, A.; Burke, R.; Sureshkumar, S.; Powell, D.; Balasubramanian, S.

10.1101/2024.03.21.586179 — genetics — Posted on 2024-03-27

891 Gene regulatory network co-option is sufficient to induce a morphological novelty in Drosophila

Rice, G. R.; Gaitan-Escudero, T.; Charles-Obi, K.; Zeitlinger, J.; Rebeiz, M.

10.1101/2024.03.22.584840 — evolutionary biology — Posted on 2024-03-27

892 From presence/absence to reliable prey proportions: A field test of dietary DNA for characterizing seabird diets

Clucas, G. V.; Stillman, A.; Craig, E. C.

10.1101/2024.03.22.586275 — ecology — Posted on 2024-03-27

893 Rhizosphere Mysteries: Metabolite Reduction Down-regulated Fungal Diversity and Community Function

Li, J.

10.1101/2024.03.22.586285 — ecology — Posted on 2024-03-27

894 TreeCompR: Tree competition indices for inventory data and 3D point clouds

Rieder, J. S.; Link, R. M.; Köthe, K.; Seidel, D.; Ullmann, T.; Zmegac, A.; Zang, C.; Schuldt, B.

10.1101/2024.03.23.586379 — ecology — Posted on 2024-03-27

895 Sediment-associated processes drive spatial variation in ecosystem respiration in the Yakima River basin

Kaufman, M.; Garayburu-Caruso, V.; Forbes, B.; Lin, X.; Hall, R.; Fulton, S.; Renteria, L.; Fang, Y.; Son, K.; Stegen, J. C.

10.1101/2024.03.22.586339 — ecology — Posted on 2024-03-27

896 Diversity and abundance of tree microhabitats in the tropical forests of southern Western Ghats, India

Patel, B.; Sivaraman, S.; Hrideek, T. K.; Balakrishnan, P.

10.1101/2024.03.23.586393 — ecology — Posted on 2024-03-27

897 Temporal constraints on enhancer usage shape the regulation of limb gene transcription

Rouco, R.; Rauseo, A.; Sapin, G.; Bompadre, O.; Darbellay, F.; Andrey, G.

10.1101/2024.03.22.585864 — developmental biology — Posted on 2024-03-27

898 Initiation and Formation of Stereocilia during the Development of Mouse Cochlear Hair Cells

Chakravarthy, S. R.; van Zanten, T. S.; Ladher, R. K.

10.1101/2024.03.23.586377 — developmental biology — Posted on 2024-03-27

899 Unusual lineage plasticity revealed by YY1 knockout in pro-B cells

Banerjee, S.; Sanyal, S.; Hodawadekar, S.; Naiyer, S.; Bano, N.; Banerjee, A.; Rhoades, J.; Dong, D.; Allman, D.; Atchison, M. L.

10.1101/2024.03.22.586298 — developmental biology — Posted on 2024-03-27

900 The Outer Kinetochore Proteins KNL-1 and Ndc80 complex are Required to Pattern the Central Nervous System

Cheerambathur, D. K.; Ouzounidis, V. R.; Green, M.; Crellin, H.; de Ceuninck, C.; Gebhardt, C.; Finlayson, C.; Prevo, B.

10.1101/2024.03.27.586904 — cell biology — Posted on 2024-03-27

901 The FAM114A proteins are adaptors for the recycling of Golgi enzymes

Welch, L. G.; Muschalik, N.; Munro, S.

10.1101/2024.03.27.587010 — cell biology — Posted on 2024-03-27

902 A Hollow TFG Condensate Spatially Compartmentalizes the Early Secretory Pathway

Wegeng, W. R.; Bogus, S. M.; Ruiz, M.; Chavez, S. R.; Noori, K. S. M.; Niesman, I. R.; Ernst, A. M.

10.1101/2024.03.26.586876 — cell biology — Posted on 2024-03-27

903 RNase L-induced bodies sequester subgenomic flavivirus RNAs and re-establish host RNA decay

Watkins, J. M.; Burke, J.

10.1101/2024.03.25.586660 — cell biology — Posted on 2024-03-27

904 Longitudinal analysis of Flower-dependent cell competition fitness markers in Drosophila melanogaster

Reis, M.; Hauert, B.; Moreno, E.

10.1101/2024.03.25.586630 — cell biology — Posted on 2024-03-27

905 The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth

Edman, S.; Jones, R. G.; Jannig, P. R.; Fernandez-Gonzalo, R.; Norrbom, J.; Thomas, N. T.; Khadgi, S.; Koopmans, P. J.; Morena, F.; Peterson, C. S.; Scott, L. N.; Greene, N. P.; Figueiredo, V. C.; Fry, C. S.; Zhengye, L.; Lanner, J. T.; Wen, Y.; Alkner, B.; Murach, K. A.; von Walden, F.

10.1101/2024.03.26.586857 — cell biology — Posted on 2024-03-27

906 The Evolutionary Origins and Ancestral Features of Septins

Delic, S.; Shuman, B.; Lee, S.; Bahmanyar, S.; Momany, M.; Onishi, M.

10.1101/2024.03.25.586683 — cell biology — Posted on 2024-03-27

907 Lysosomal storage disease proteo/lipidomic profiling using nMOST links ferritinophagy with mitochondrial iron deficiencies in cells lacking NPC2

Harper, J. W.; Kraus, F.; He, Y.; Swarup, S.; Overmyer, K. A.; Brenner, J.; Capitanio, C.; Bieber, A.; Jen, A.; Nightingale, N. M.; Anderson, B. J.; Lee, C.; Paulo, J. A.; Smith, I. R.; Plitzko, J. M.; Schulman, B. A.; Wilfling, F.; Coon, J. J.

10.1101/2024.03.26.586828 — cell biology — Posted on 2024-03-27

908 Morphoregulatory ADD3 underlies glioblastoma growth and formation of tumor-tumor connections

Barelli, C.; Kaluthantrige Don, F.; Iannuzzi, R. M.; Bertani, I.; Osei, I.; Sorrentino, S.; Villa, G.; Sokolova, V.; Iorio, F.; Kalebic, N.

10.1101/2024.03.26.586725 — cell biology — Posted on 2024-03-27

909 Basal association of a transcription factor favors early gene expression

Pinheiro, S.; Vincenzetti, V.; Dusserre, Y.; Pelet, S.

10.1101/2024.03.26.586726 — cell biology — Posted on 2024-03-27

910 Liver regeneration by oval cells employing bistability of stemness-senescence, Hippo signaling, EMT-MET, and polyploidy circuit

Lazovska, M.; Salmina, K.; Pjanova, D.; Gerashchenko, B. I.; Erenpreisa, J.

10.1101/2024.03.26.586724 — cell biology — Posted on 2024-03-27

911 Fibroblasts enhance the growth and survival of adult feline small intestinal organoids

Hryckowian, N. D.; Studener, K.; Knoll, L.

10.1101/2024.03.26.586790 — cell biology — Posted on 2024-03-27

912 Glutaminase deficiency in rod photoreceptors disrupts nonessential amino acid levels to activate the integrated stress response and induce rapid degeneration

Goswami, M. T.; Weh, E.; Subramanya, S.; Weh, K. M.; Durumutla, H. B.; Hager, H.; Miller, N.; Chaudhury, S.; Andren, A.; Sajjakulnukit, P.; Besirli, C. G.; Lyssiotis, C. A.; Wubben, T. J.

10.1101/2024.03.26.582525 — cell biology — Posted on 2024-03-27

913 Sexually dimorphic effects of prenatal alcohol exposure on the murine skeleton

Bourne, L. E.; Jayash, S. N.; Michels, L. V.; Hopkinson, M.; Guppy, F. M.; Clarkin, C. E.; Gard, P.; Brissett, N.; Staines, K. A.

10.1101/2024.03.27.586945 — cell biology — Posted on 2024-03-27

914 Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output

Lessenger, A. T.; Swaffer, M. P.; Skotheim, J. M.; Feldman, J. L.

10.1101/2024.03.25.586714 — cell biology — Posted on 2024-03-27

915 The Scribble/SGEF/Dlg1 complex regulates the stability of apical junctions in epithelial cells

Rabino, A. F.; Awadia, S.; Ali, N. N.; Edson, A. L.; Garcia-Mata, R.

10.1101/2024.03.26.586884 — cell biology — Posted on 2024-03-27

916 BAX and BAK expression triggers multiple IRE1 signaling outputs under ER stress

Sepulveda, C.; Milani, M.; Morales, V.; Tamburini, G.; Montes, N.; Hetz, C.

10.1101/2024.03.26.586784 — cell biology — Posted on 2024-03-27

917 Tetraspanin-enriched microdomains play an important role in pathogenesis in the protozoan parasite Entamoeba histolytica

Jiang, H.; Santos, H. J.; Nozaki, T.

10.1101/2024.03.27.586913 — cell biology — Posted on 2024-03-27

918 Rapid Homolog Juxtaposition During Meiotic Chromosome Pairing

Nozaki, T.; Weiner, B.; Kleckner, N.

10.1101/2024.03.23.586418 — molecular biology — Posted on 2024-03-27

919 A molecular switch orchestrates the nuclear export of human messenger RNA

Hohmann, U.; Graf, M.; Schellhaas, U.; Pacheco-Fiallos, B.; Fin, L.; Riabov-Bassat, D.; Pühringer, T.; Szalay, M.-F.; Tirian, L.; Handler, D.; Brennecke, J.; Plaschka, C.

10.1101/2024.03.24.586400 — molecular biology — Posted on 2024-03-27

920 (p)ppGpp buffers cell division when membrane fluidity decreases in Escherichia coli.

R, H.; Singh, V.

10.1101/2024.03.27.586906 — microbiology — Posted on 2024-03-27

921 Bisphosphonates synergistically enhance the antifungal activity of azoles in dermatophytes and other pathogenic molds

Kane, A. J.; Rothwell, J. G.; Guttentag, A.; Hainsworth, S.; Carter, D. A.

10.1101/2024.03.25.586613 — microbiology — Posted on 2024-03-27

922 Higher amplitudes of visual networks are associated with trait but not state- depression.

Zhang, W.; Dutt, R.; Lew, D.; Barch, D. M.; Bijsterbosch, J. D.

10.1101/2024.03.25.584801 — neuroscience — Posted on 2024-03-27

923 Single cell approaches define forebrain neural stem cell niches and identify microglial ligands that enhance precursor-mediated remyelination

Willis, A.; Jeong, D.; Liu, Y.; Lithopoulos, M. A.; Yuzwa, S.; Frankland, P. W.; Kaplan, D. R.; Miller, F. D.

10.1101/2024.03.22.586277 — neuroscience — Posted on 2024-03-27

924 Feedback and Feedforward Regulation of Interneuronal Communication

Gambrell, O.; Vahdat, Z.; Singh, A.

10.1101/2024.03.22.586312 — neuroscience — Posted on 2024-03-27

925 Altered patterning of neural activity in a tauopathy mouse model

Hoffman, C.; Cheng, J.; Morales, R.; Ji, D.; Dabaghian, Y. A.

10.1101/2024.03.23.586417 — neuroscience — Posted on 2024-03-27

926 Functional characterization of Lipid storage droplets 1 (LSD1) in growth and lipolysis of Hermetia illucens

Jiang, Y.; Kou, Z.; Chen, B.; Huang, Y.

10.1101/2024.03.22.586280 — zoology — Posted on 2024-03-27

927 Honoring the Afro-Colombian musical culture with the naming of Epipedobates sp. nov. (Anura: Dendrobatidae), a frog from the Pacific rainforests

Betancourth-Cundar, M.; Rios-Orjuela, J. C.; Crawford, A. J.; Cannatella, D. C.; Tarvin, R. D.

10.1101/2024.03.23.586415 — zoology — Posted on 2024-03-27

928 The FAIR-Device - a non-lethal and generalist semi-automatic Malaise trap for insect biodiversity monitoring: Proof of concept

Chiavassa, J. A.; Kraft, M.; Noack, P.; Walther, S.; Kirse, A.; Scherber, C.

10.1101/2024.03.22.586299 — zoology — Posted on 2024-03-27

929 Mass spectrometry-based top-down proteomics in nanomedicine: proteoform-specific measurement of protein corona

Sadeghi, S. A.; Ashkarran, A. A.; Mahmoudi, M.; sun, l.

10.1101/2024.03.22.586273 — systems biology — Posted on 2024-03-27

930 Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap)

Forrester, M. T.; Egol, J. R.; Tata, A.; Tata, P. R.; Foster, M. W.

10.1101/2024.03.23.586403 — systems biology — Posted on 2024-03-27

931 Providing Insights into Health Data Science Education through Artificial Intelligence

Rohani, N.; Gal, K.; Gallagher, M.; Manataki, A.

10.1101/2024.03.22.586308 — scientific communication and education — Posted on 2024-03-27

932 Effect of temperature on circadian clock functioning of trees in the context of global warming

Estravis-Barcala, M.; Gaischuk, S.; Gonzalez-Polo, M.; Martinez-Meier, A.; Gutierrez, R. A.; Yanovsky, M. J.; Bellora, N.; Arana, M. V.

10.1101/2024.03.22.586279 — plant biology — Posted on 2024-03-27

933 Development of a tightly regulated copper-inducible transient gene expression system in Nicotiana benthamiana incorporating suicide exon and Cre recombinase

Chiang, B.-J.; Lin, K.-Y.; Chen, Y.-F.; Huang, C.-Y.; Goh, F.-J.; Huang, L.-T.; Chen, L.-H.; Wu, C.-H.

10.1101/2024.03.23.586378 — plant biology — Posted on 2024-03-27

934 Autophagy at Crossroads: Modulating Responses to Combined Stresses, Unveiling Metabolic Shifts and Bacterial Dependencies

Seybold, H.; Katz, E.; Soroka, Y.; Avin-Wittenberg, T.

10.1101/2024.03.22.586360 — plant biology — Posted on 2024-03-27

935 Genome-wide analysis of mRNA decay in Arabidopsis shoot and root reveals the importance of co-translational mRNA decay in the general mRNA turnover

Carpentier, M.-C.; Receveur, A.-E.; Boubegtitene, A.; Cadoudal, A.; Bousquet-Antonelli, C.; Merret, R.

10.1101/2024.03.23.586374 — plant biology — Posted on 2024-03-27

936 Genome-Wide Identification and Comprehensive Analysis of the SBT Gene Family in Soybean (Glycine max)

He, X.; He, S. h.; Yang, J. x.; Yue, Z. y.

10.1101/2024.03.27.586907 — plant biology — Posted on 2024-03-27

937 Telomere Length in Plants Estimated with Long Read Sequencing

Colt, K.; Petrus, S.; Abramson, B. W.; Mamerto, A.; Hartwick, N. T.; Michael, T. P.

10.1101/2024.03.27.586973 — plant biology — Posted on 2024-03-27

938 Diurnal regulation of SOS Pathway and Sodium Excretion Underlying Salinity Tolerance of Vigna marina

Noda, Y.; Wang, F.; Chankaew, S.; Ariga, H.; Muto, C.; Iki, Y.; Ohashi, H.; Takahashi, Y.; Sakai, H.; Iseki, K.; Ogiso-Tanaka, E.; Suzui, N.; Yin, Y.-G.; Miyoshi, Y.; Enomoto, K.; Kawachi, N.; Somta, P.; Furukawa, J.; Tomooka, N.; Naito, K.

10.1101/2024.03.26.586888 — plant biology — Posted on 2024-03-27

939 Glucosylceramides impact cellulose deposition and cellulose synthase complex motility in Arabidopsis

Villalobos, J. A.; Cahoon, R. E.; Cahoon, E. B.; Wallace, I. S.

10.1101/2024.03.25.585105 — plant biology — Posted on 2024-03-27

940 TFIIS is required for reproductive development and thermal adaptation in barley

Ahmad, I.; Andras, K.; Verma, R.; Szadeczky-Kardoss, I.; Szaker, H. M.; Pettko-Szandtner, A.; Silhavy, D.; Havelda, Z.; Csorba, T.

10.1101/2024.03.26.586761 — plant biology — Posted on 2024-03-27

941 An efficient inducible model for the control of gene expression in renin cells

Medrano, S.; Yamaguchi, M.; Yamaguchi, H.; Almeida, L.; Sigmund, C.; Sequeira-Lopez, M. L. S.; Gomez, A.

10.1101/2024.03.26.585202 — physiology — Posted on 2024-03-27

942 A 6-minute Limb Function Assessment for Therapeutic Testing in Experimental Peripheral Artery Disease Models

Palzkill, V.; Tan, J.; Tice, A. L.; Ferreira, L. F.; Ryan, T. E.

10.1101/2024.03.21.586197 — physiology — Posted on 2024-03-27

943 Broad therapeutic benefit of myosin inhibition in hypertrophic cardiomyopathy

Sen Martin, L.; Fernandez Trasancos, A.; Lopez Unzu, M. A.; Pathak, D.; Ferrarini, A.; Labrador Cantarero, V.; Sanchez Ortiz, D.; Pricolo, M. R.; Vicente, N.; Velazquez Carreras, D.; Sanchez Garcia, L.; Nicolas Avila, J. A.; Sanchez Diaz, M.; Schlossarek, S.; Cusso, L.; Desco, M.; Villalba Orero, M.; Guzman Martinez, G.; Calvo, E.; Barriales Villa, R.; Vazquez, J.; Sanchez Cabo, F.; Hidalgo, A.; Carrier, L.; Spudich, J.; Ruppel, K. M.; Alegre Cebollada, J.

10.1101/2024.03.22.584986 — physiology — Posted on 2024-03-27

944 ELO-6 expression predicts longevity in isogenic populations of Caenorhabditis elegans

Kong, W.; Gu, G.; Dai, T.; Chen, B.; Pu, M.

10.1101/2024.03.23.585832 — physiology — Posted on 2024-03-27

945 Screening and characterization of 133 physiologically-relevant environmental chemicals for reproductive toxicity

Ulaganathan, G.; Jiang, H.; Canio, N.; Oke, A.; Armstrong, S. S.; Abrahamsson, D.; Varshavsky, J. R.; Lam, J.; Cooper, C.; Robinson, J. F.; Fung, J.; Woodruff, T. J.; Allard, P.

10.1101/2024.03.22.584808 — pharmacology and toxicology — Posted on 2024-03-27

946 Development of quantitative high-throughput screening assays to identify, validate, and optimize small-molecule stabilizers of misfolded β-glucocerebrosidase with therapeutic potential for Gaucher disease and Parkinson's disease

Williams, D.; Glasstetter, L. M.; Jong, T. T.; Kapoor, A.; Zhu, S.; Zhu, Y.; Gehrlein, A.; Vocadlo, D. J.; Jagasia, R.; Marugan, J. J.; Sidransky, E.; Henderson, M. J.; Chen, Y.

10.1101/2024.03.22.586364 — pharmacology and toxicology — Posted on 2024-03-27

947 TAK1-mediated phosphorylation of PLCE1 represses PIP2 hydrolysis to impede esophageal squamous cancer metastasis

Ju, Q.; Sheng, W.; Zhang, M.; Chen, J.; Wu, L.; Liu, X.; Fang, W.; Shi, H.; Sun, C.

10.1101/2024.03.22.586256 — cancer biology — Posted on 2024-03-27

948 Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma

Teisseire, M.; Sahu, U.; Parola, J.; Tsai, M.-C.; Vial, V.; Durivault, J.; Grepin, R.; Cormerais, Y.; Pages, G.; Ben-Sahra, I.; Giuliano, S.

10.1101/2024.03.22.586287 — cancer biology — Posted on 2024-03-27

949 Targeting Fatty Acid Desaturase I Inhibits Renal Cancer Growth Via ATF3-mediated ER Stress Response

Heravi, G.; Liu, Z.; Herroon, M.; Wilson, A.; Fan, Y. Y.; Jiang, Y.; Vakeesan, N.; Tao, L.; Peng, Z.; Zhang, K.; Li, J.; Chapkin, R. S.; Podgorski, I.; Liu, W.

10.1101/2024.03.23.586426 — cancer biology — Posted on 2024-03-27

950 Androgen receptor-negative prostate cancer is vulnerable to SWI/SNF-targeting degrader molecules

Thienger, P. D.; Rubin, P. D.; Yao, X.; Benjak, A.; Shah, S.; King-Yung Leung, A.; de Brot, S.; Naveed, A.; Shi, M.; Tremblay, J.; Triscott, J.; Cassanmagnano, G.; Bolis, M.; Mela, L.; Beltran, H.; Chen, Y.; Piscuoglio, S.; Yu, H.; Ng, C. K.; Yauch, R.; Rubin, M. A.

10.1101/2024.03.24.586276 — cancer biology — Posted on 2024-03-27

951 An Innovative Mitochondrial-targeted Gene Therapy for Cancer Treatment

Chen, K.; Ernst, P.; Kim, S.; Si, Y.; Varadkar, T.; Ringel, M.; Liu, X.; Zhou, L.

10.1101/2024.03.24.584499 — cancer biology — Posted on 2024-03-27

952 Characterizing the Binding Mechanism of Sparsentan to the Type-2 Angiotensin II Receptor Using AutoDock Vina

Geng, P. X.

10.1101/2024.03.22.586129 — biophysics — Posted on 2024-03-27

953 Integrating Chromosome Conformation and DNA Repair in a Computational Framework to Assess Cell Radiosensitivity

Andriotty, M.; Wang, C.-K. C.; Kapadia, A.; McCord, R. P.; Agasthya, G.

10.1101/2024.03.25.586626 — biophysics — Posted on 2024-03-27

954 Exploring ligands that target von Willebrand factor selectively under oxidizing conditions through docking and molecular dynamics simulations

Interlandi, G.

10.1101/2024.03.22.586354 — biophysics — Posted on 2024-03-27

955 Dynamic fibrillar assembly of αB-crystallin induced by perturbation of the conserved NT-IXI motif resolved by cryo-EM.

Reichow, S. L.; McFarland, R.

10.1101/2024.03.22.586355 — biophysics — Posted on 2024-03-27

956 A realistic algorithm for microtubule-based nucleation reveals large sensitivity to cell geometry of the plant cortical array

Saltini, M.; Deinum, E. E.

10.1101/2024.03.25.586463 — biophysics — Posted on 2024-03-27

957 Self-quenched fluorophore-DNA labels for super-resolution fluorescence microscopy

Kessler, L. F.; Balakrishnan, A.; Menche, T.; Wang, D.; Li, Y.; Mantel, M.; Glogger, M.; Dietz, M. S.; Heilemann, M.

10.1101/2024.03.24.586443 — biophysics — Posted on 2024-03-27

958 Flanking Domains Modulate α-Synuclein Monomer Structure: A Molecular Dynamics Domain Deletion Study

Onishi, N.; Mazzaferro, N.; Kunstelj, S.; Alvarado, D.; Muller, A.; Vazquez, F. X.

10.1101/2024.03.23.586267 — biophysics — Posted on 2024-03-27

959 QuartPlotR: A quarternary phase diagram tool

Veluchamy, A.; Bowler, C.

10.1101/2024.03.22.586216 — bioinformatics — Posted on 2024-03-27

960 FLIGHTED: Inferring Fitness Landscapes from Noisy High-Throughput Experimental Data

Sundar, V.; Tu, B.; Guan, L.; Esvelt, K.

10.1101/2024.03.26.586797 — bioinformatics — Posted on 2024-03-27

961 A*PA2: up to 20 times faster exact global alignment

Groot Koerkamp, R.

10.1101/2024.03.24.586481 — bioinformatics — Posted on 2024-03-27

962 PhosX: data-driven kinase activity inference from phosphoproteomics experiments

Lussana, A.; Petsalaki, E.

10.1101/2024.03.22.586304 — bioinformatics — Posted on 2024-03-27

963 Exploring the distribution of single nucleotide polymorphisms across human exons and introns

Fraszczak, M.; Liu, J.; Mielczarek, M.; Dobosz, P.; Szyda, J.

10.1101/2024.03.23.586436 — bioinformatics — Posted on 2024-03-27

964 Exploring Pathogenic Mutation in Allosteric Proteins: the Prediction and Beyond

Zhang, H.; Ju, Z.; Zhang, J.; Li, X.; Xiao, H.; Chen, X.; Li, Y.; Wang, X.; Wei, Y.

10.1101/2024.03.23.586438 — bioinformatics — Posted on 2024-03-27

965 OmicsFootPrint: a framework to integrate and interpret multi-omics data using circular images and deep neural networks

Tang, X.; Prodduturi, N.; Thompson, K. J.; Weinshilboum, R. M.; O'Sullivan, C. C.; Boughey, J. C.; Tizhoosh, H.; Klee, E. W.; Wang, L.; Goetz, M. P.; Suman, V.; Kalari, K. R.

10.1101/2024.03.21.586001 — bioinformatics — Posted on 2024-03-27

966 Modeling of chemo-radiotherapy targeting growing vascular tumors: a continuum-level approach

Lampropoulos, I. A.; Koutsi, M.; Kavousanakis, M.

10.1101/2024.03.21.586183 — bioengineering — Posted on 2024-03-27

967 MICROMANIPULATION OF LIVE MICRODISSECTED TISSUES WITH A LOW-COST INTEGRATED ROBOTIC PLATFORM

Gottshall, N. R.; Stepanov, I.; Ahmadianyazdi, A.; Sinha, D.; Lockhart, E.; Nguyen, T. N.; Hassan, S.; Horowitz, L.; Yeung, R.; Gujral, T. S.; Folch, A.

10.1101/2024.03.21.586169 — bioengineering — Posted on 2024-03-27

968 Overexpression of Sirohydrochlorin Ferrochelatase Boosts Nitrogen Sulfur and Carbon Utilization in Arabidopsis thaliana

Joshi, N. C.; Tripathy, B. C.

10.1101/2024.03.22.586315 — bioengineering — Posted on 2024-03-27

969 Engineered Flt3L Drives Tolerogenic State to Attenuate Anti-drug Antibody Responses

Alpar, A. T.; Wallace, R. P.; Refvik, K. C.; Gomes, S.; Solanki, A.; Gray, L. T.; Slezak, A. J.; Lauterbach, A. L.; Hesser, L. A.; Cao, S.; Medellin, J. E. G.; Robinson, L. G.; Hubbell, J. A.

10.1101/2024.03.21.586168 — bioengineering — Posted on 2024-03-27

970 A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation

Nguyen, V. C. B.; Özden, C.; Dong, K.; Torres-Ocampo, A. P.; Dziedzic, N.; Flaherty, D.; Huang, J.; Sankura, S.; Abromson, N. L.; Tomchick, D. R.; Chen, J.; Garman, S. C.; Stratton, M.

10.1101/2024.03.24.586494 — biochemistry — Posted on 2024-03-27

971 Long Amplicon Nanopore Sequencing for Dual-Typing RdRp and VP1 Genes of Norovirus Genogroups I and II in Wastewater

Scott, G.; Ryder, D.; Buckley, M.; Hill, R.; Treagus, S.; Stapleton, T.; Walker, D. I.; Lowther, J.; Batista, F. M.

10.1101/2024.03.27.584784 — molecular biology — Posted on 2024-03-27

972 Bacterial-tyramine-induced renal-gut countercurrent flow regulates gut immune response by promoting ROS accumulation and gut peristalsis in the fly Bactrocera dorsalis

Liu, Y.; Luo, R.; Lamaitre, B.; Zhang, H.; Li, X.

10.1101/2024.03.22.586092 — immunology — Posted on 2024-03-27

973 Novel non-immunogenic trained immunity inducing small molecule with improved anti-tumor properties

Ajit, J.; Knight, H. R.; Chen, Q.; Solanki, A.; Shen, J.; Esser-Kahn, A. P.

10.1101/2024.03.22.585780 — immunology — Posted on 2024-03-27

974 One signal activated TIL enable potent anti-tumor activity across diverse solid tumor types

Wu, Y.; ye, x. s.; Zhu, Y.; Yuan, Q.; Kong, D.; Zhao, L.

10.1101/2024.03.21.586203 — immunology — Posted on 2024-03-27

975 Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation

Caetano-Silva, M. E.; Shrestha, A.; Duff, A. F.; Kontic, D.; Brewster, P. C.; Kasperek, M. C.; Lin, C. H.; Wainwright, D. A.; Saavedra, D. H.; Woods, J. A.; Bailey, M. T.; Buford, T. W.; Allen, J. M.

10.1101/2024.03.22.586320 — immunology — Posted on 2024-03-27

976 Single cell resolution analysis of multi-tissue derived human iNKT cells reveals novel transcriptional paradigms

Jayasinghe, R. G.; Hollingsworth, D.; Boonchalermvichian, C.; Gupta, B.; Yan, H.; Baker, J.; Dejene, B.; Weinberg, K. I.; Negrin, R. S.; Mavers, M.

10.1101/2024.03.22.583992 — immunology — Posted on 2024-03-27

977 Retinal microglia exacerbate uveitis by functioning as local antigen-presenting cells

Shirahama, S.; Okunuki, Y.; Lee, M. Y.; Karg, M. M.; Refaian, N.; Krasniqi, D.; Connor, K. M.; Gregory-Ksander, M. S.; Ksander, B. R.

10.1101/2024.03.23.586440 — immunology — Posted on 2024-03-27

978 Investigating Cryopreserved PBMC Functionality in an Antigen-Induced Model of Sarcoidosis Granuloma Formation

Seman, S. G.; Bicer, S.; Julian, M. W.; Kramer, P. J.; Mitchell, J. R.; Crouser, E. D.; LOCKE, L. W.

10.1101/2024.03.23.586344 — immunology — Posted on 2024-03-27

979 Role of Posterior Medial Thalamus in the Modulation of Striatal Circuitry and Choice Behavior

Yonk, A. J.; Linares-Garcia, I.; Pasternak, L.; Juliani, S. E.; Gradwell, M. A.; George, A. J.; Margolis, D. J.

10.1101/2024.03.21.586152 — neuroscience — Posted on 2024-03-27

980 Arginine vasopressin activates serotonergic neurons in the dorsal raphe nucleus during neonatal development in vitro and in vivo

Orav, E.; Kokinovic, B.; Teppola, H.; Siimon, M.; Lauri, S. E.; Hartung, H.

10.1101/2024.03.22.586208 — neuroscience — Posted on 2024-03-27

981 Distinct and Asymmetric Neuronal Responses to Pitch- and Roll-Axis Vestibular Stimulation in larval zebrafish

Migault, G.; Beiza-Canelo, N.; Chatterjee, S.; Debregeas, G.; Bormuth, V.

10.1101/2024.03.22.586054 — neuroscience — Posted on 2024-03-27

982 Enhancing tonic arousal improves voluntary but not involuntary attention in humans

Grandjean, A.; Mathieu, A.; Chen, S.; Widmann, A.; Wetzel, N.; Bidet-Caulet, A.

10.1101/2024.03.22.586259 — neuroscience — Posted on 2024-03-27

983 Switching between newly learned motor skills

Kita, K.; Du, Y.; Haith, A. M.

10.1101/2024.03.22.586357 — neuroscience — Posted on 2024-03-27

984 Implantable Bioelectronics for Real-time in vivo Recordings of Enteric Neural Activity

Boys, A. J.; Güemes, A. J.; Gupta, R. A.; Uhlig, F. H.; Hyland, N. P.; Bulmer, D. C.; Malliaras, G. G.; Owens, R. M.

10.1101/2024.03.22.586292 — neuroscience — Posted on 2024-03-27

985 Multidimensional analysis of cortical interneuron synaptic features reveals underlying synaptic heterogeneity

Dummer, P.; Lee, D.; Hossain, S.; Wang, R.; Evard, A.; Schneider-Mizell, C. M.; Menon, V.; Au, E.

10.1101/2024.03.22.586340 — neuroscience — Posted on 2024-03-27

986 Basal ganglia output - entopeduncular nucleus - coding of contextual kinematics and reward in the freely moving mouse

Verma-Rodriguez, A. K.; Ramirez-Jarquin, J. O.; Rossi-Pool, R.; Tecuapetla, F.

10.1101/2024.03.22.586140 — neuroscience — Posted on 2024-03-27

987 Modeling responses of macaque and human retinal ganglion cells to natural images using a convolutional neural network

Gogliettino, A. R.; Cooler, S.; Vilkhu, R. S.; Brackbill, N. J.; Rhoades, C.; Wu, E. G.; Kling, A.; Sher, A.; Litke, A. M.; Chichilnisky, E. J.

10.1101/2024.03.22.586353 — neuroscience — Posted on 2024-03-27

988 Spectral graph model for fMRI: a biophysical, connectivity-based generative model for the analysis of frequency-resolved resting state fMRI

Raj, A.; Sipes, B. S.; Verma, P.; Mathalon, D. H.; Biswal, B. B.; Nagarajan, S. S.

10.1101/2024.03.22.586305 — neuroscience — Posted on 2024-03-27

989 A functional overlap between evidence accumulation, confidence, and changes of mind in the pre-supplementary motor area and insula

Goueytes, D.; Stockart, F.; Robin, A.; Gyger, L.; Rouy, M.; Hoffmann, D.; Minotti, L.; Kahane, P.; Pereira, M.; Faivre, N.

10.1101/2024.03.23.586414 — neuroscience — Posted on 2024-03-27

990 Mobile EEG for Neurourbanism Research - What Could Possibly Go Wrong?A Critical Review with Guidelines

Gramann, K.

10.1101/2024.03.22.586309 — neuroscience — Posted on 2024-03-27

991 Ribosome biogenesis factor AtRRB1 confers pollen heat stress tolerance in Arabidopsis

Jin, C.; Schindfessel, C.; Sun, L.; Keceli, B. N.; Vanneste, S.; Geelen, D.

10.1101/2024.03.21.586164 — plant biology — Posted on 2024-03-27

992 Microdissected tumor cuboids: a microscale cancer model that retains a complex tumor microenvironment

Horowitz, L. F.; Rodriguez-Mias, R. A.; Zhu, S.; Gottshall, N. R.; Stepanov, I.; Stiles, C.; Yeung, M.; Nguyen, T. N.; Lockhart, E. J.; Yeung, R. S.; Villen, J.; Gujral, T. S.; Folch, A.

10.1101/2024.03.22.586189 — cancer biology — Posted on 2024-03-27

993 An Integrated Machine Learning Approach Delineates Entropy-mediated Conformational Modulation of α-synuclein by Small Molecule

Menon, S.; Adhikari, S.; Mondal, J.

10.1101/2024.01.15.575555 — biophysics — Posted on 2024-03-27

994 Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain

Haider, R.; Shipley, B. E.; Surewicz, K.; Hinczewski, M.; Surewicz, W. K.

10.1101/2024.03.21.586202 — biophysics — Posted on 2024-03-27

995 MelAnalyze: Fact-Checking Melatonin claims using Large Language Models and Natural Language Inference

Palaniappan, S. K.; Karkera, N.; Ghosh, S.

10.1101/2024.03.21.586201 — bioinformatics — Posted on 2024-03-27

996 Accelerated dimensionality reduction of single -cell RNA sequencing data with fastglmpca

Weine, E.; Carbonetto, P.; Stephens, M.

10.1101/2024.03.23.586420 — bioinformatics — Posted on 2024-03-27

997 Exploring the impact of sequence context on errors in SNP genotype calling with Whole Genome Sequencing data using AI-based autoencoder approach

Kotlarz, K.; Mielczarek, M.; Biecek, P.; Guldbrandtsen, B.; Szyda, J.

10.1101/2024.03.23.586433 — bioinformatics — Posted on 2024-03-27

998 Cross Modal Correspondence based MultisensoryIntegration: A pilot study showing how HAV cues can modulate the reaction time.

BANERJEE, S.

10.1101/2024.03.21.586134 — animal behavior and cognition — Posted on 2024-03-27

999 BLOC1S1 control of vacuolar organelle fidelity modulates TH2 cell immunity and allergy susceptibility.

Sharma, R.; Wu, K.; Han, K.; Russo, A. C.; Dagur, P. K.; Combs, C. A.; Sack, M. N.

10.1101/2024.03.21.586144 — immunology — Posted on 2024-03-27

1000 34-parameter full spectrum immunophenotyping panel of human regulatory and effector lymphocytes

Georgieva, Z.; Coppard, V.; Yang, J. H.; Grenfell, R.; Jones, J. L.

10.1101/2024.03.21.585958 — immunology — Posted on 2024-03-27

1001 Hierarchal single-cell lineage tracing reveals differential fate commitment of CD8 T-cell clones in response to acute infection.

Abdullah, L.; Emiliani, F. E.; Vaidya, C. M.; Stuart, H.; Kolling, F. W.; Ackerman, M. E.; Song, L.; McKenna, A.; Huang, Y. H.

10.1101/2024.03.21.586160 — immunology — Posted on 2024-03-27

1002 State-dependent Online Reactivations for Different Learning Strategies in Foraging

Son, S.; Wang, M. Z.; Hayden, B. Y.; Yoo, S. B. M.

10.1101/2024.03.25.586512 — neuroscience — Posted on 2024-03-27

1003 Link between respiratory pauses and vigilance states in freely moving mice

Casali, G.; Miermon, C.; Terral, G.; Ravassard, P.; Dolique, T.; Lesburgueres, E.; Jarriault, D.; Gambino, F.; Chenouard, N.; Roux, L.

10.1101/2024.03.27.586921 — neuroscience — Posted on 2024-03-27

1004 An inhibitory acetylcholine receptor gates context dependent mechanosensory processing in C. elegans

Kumar, S.; Sharma, A. K.; Leifer, A. M.

10.1101/2024.03.21.586204 — neuroscience — Posted on 2024-03-27

1005 The smoking cessation drug cytisine requires systemically circulating estrogen for sex-specific neuroprotection in female parkinsonian mice

Zarate, S. M.; Garcia, R. C.; Pandey, G.; Srinivasan, R.

10.1101/2024.03.21.586192 — neuroscience — Posted on 2024-03-27

1006 Surface-based probabilistic tractography uncovers segregated white matter pathways underlying spatial and non-spatial control

Bedini, M.; Olivetti, E.; Avesani, P.; Baldauf, D.

10.1101/2024.03.21.585573 — neuroscience — Posted on 2024-03-27

1007 The Genomes of Nematode-Trapping Fungi Provide Insights into the Origin and Diversification of Fungal Carnivorism

Fan, Y.; Du, M.; Zhang, W.; Deng, W.; Yang, E.; Wang, S.; Yan, L.; Zhang, L.; Kang, S.; Steenwyk, J. L.; An, Z.; Liu, X.; Xiang, M.

10.1101/2024.03.21.586190 — evolutionary biology — Posted on 2024-03-27

1008 Whole-genome resequencing revealed the Origin and Domestication of Chinese Domestic Rabbits

Xie, K.; Song, Z.; Wang, Y.; Di, Y.; Li, W.; Wang, Y.; Yang, A.; Qiao, X.; Wang, B.; Li, M.; Xie, X.; Xie, X.; Liu, L.; Ning, C.; Tang, H.; Li, X.; Wu, X.; Wang, D.; Fan, X.

10.1101/2024.03.26.586758 — evolutionary biology — Posted on 2024-03-27

1009 Accelerated Bayesian inference of population size history from recombining sequence data

Terhorst, J.

10.1101/2024.03.25.586640 — evolutionary biology — Posted on 2024-03-27

1010 Estimating Organ-to-Plasma Ratios in physiologically based PK modeling: a simplified approach for early drug discovery

Broccatelli, F.; Ramakrishnan, R.

10.1101/2024.03.21.586167 — pharmacology and toxicology — Posted on 2024-03-27

1011 The Sociodemographic and Lifestyle Correlates of Epigenetic Aging in a Nationally Representative U.S. Study of Younger Adults

Harris, K. M.; Levitt, B. E.; Gaydosh, L.; Martin, C.; Meyer, J. M.; Mishra, A. A.; Kelly, A. L.; Aiello, A. E.

10.1101/2024.03.21.585983 — genomics — Posted on 2024-03-27

1012 Mapping the distribution of seagrass meadows from space with deep convolutional neural networks

Gimenez-Romero, A.; Ferchichi, D.; Moreno-Spiegelberg, P.; Sintes, T.; Matias, M. A.

10.1101/2024.03.21.586047 — ecology — Posted on 2024-03-27

1013 The Pulfrich Effect in Virtual Reality

LoPrete, A.; Shapiro, A. G.

10.1101/2024.03.21.585956 — neuroscience — Posted on 2024-03-27

1014 Alpha Traveling Waves during Working Memory: Disentangling Bottom-up Gating and Top-down Gain Control

Zeng, Y.; Sauseng, P.; Alamia, A.

10.1101/2024.03.21.586061 — neuroscience — Posted on 2024-03-27

1015 Parallel Multilink Group Joint ICA: Fusion of 3D Structural and 4D Functional Data Across Multiple Resting fMRI Networks

Khalilullah, K. M. I.; Agcaoglu, O.; Sui, J.; Duda, M.; Adali, T.; Calhoun, V. D.

10.1101/2024.03.21.586091 — neuroscience — Posted on 2024-03-27

1016 A Systematic Assessment of Robustness in CNS Safety Pharmacology

Reiber, M.; Stirling, H.; Ahuis, T. P.; Arias, W.; Aulehner, K.; Dressler, U.; Kas, M. J. H.; Kela, J.; Kerker, K.; Kuosmanen, T.; Lorenz, H.; Pennington, A. T.; von Ruden, E.-L.; Schauerte, H.; Seiffert, I.; Talbot, S. R.; Torturo, C.; Virtanen, S.; Waldron, A.-M.; Ramboz, S.; Potschka, H.

10.1101/2024.03.21.586096 — neuroscience — Posted on 2024-03-27

1017 Operation regimes of spinal circuits controlling locomotion and role of supraspinal drives and sensory feedback

Rybak, I. A.; Shevtsova, N. A.; Markin, S. N.; Prilutsky, B. I.; Frigon, A.

10.1101/2024.03.21.586122 — neuroscience — Posted on 2024-03-27

1018 The technical-reasoning network is recruited when people observe others make or teach how to make tools: An fMRI study

Bluet, A.; Reynaud, E.; Federico, G.; Bryche, C.; Lesourd, M.; Fournel, A.; Lamberton, F.; Ibarrola, D.; Rossetti, Y.; Osiurak, F.

10.1101/2024.03.21.586121 — neuroscience — Posted on 2024-03-27

1019 Parallel maturation of hippocampal memory and CA1 task representations

Bevandic, J.; Stella, F.; Olafsdottir, H. F.

10.1101/2024.03.21.585945 — neuroscience — Posted on 2024-03-27

1020 Evidence for common spike-based temporal coding of overt and covert speech in pars triangularis of human Broca's area

Roussel, P.; Bocquelet, F.; Chabardes, S.; Yvert, B.

10.1101/2024.03.21.586130 — neuroscience — Posted on 2024-03-27

1021 Dorsolateral septum GLP-1R neurons regulate feeding via lateral hypothalamic projections

Lu, Y.; Wang, L.; Luo, F.; Savani, R.; Rossi, M. A.; Pang, Z. P.

10.1101/2024.03.26.586855 — neuroscience — Posted on 2024-03-27

1022 Edinger-Westphal ghrelin receptor signalling regulates binge alcohol consumption in a sex specific manner

Pearl, A.; Pinares-Garcia, P.; Shesham, A.; Maddern, X.; Anversa, R.; Brown, R.; Reed, F. M.; Giardino, W.; Lawrence, A. J.; Walker, L.

10.1101/2024.03.23.586439 — neuroscience — Posted on 2024-03-27

1023 Pharmacological stimulation of infralimbic cortex after fear conditioning facilitates subsequent fear extinction

Bayer, H.; Hassell, J. E.; Oleksiak, C. R.; Garcia, G. M.; Vaughan, H.; Juliano, V. A. L.; Maren, S.

10.1101/2024.03.23.586410 — neuroscience — Posted on 2024-03-27

1024 Muscle-resident mesenchymal progenitors sense and repair peripheral nerve injury via the GDNF-BDNF axis

Yoo, K.; Jo, Y.-W.; Yoo, T.; Hann, S.-H.; Park, I.; Kim, Y.-E.; Kim, Y. L.; Rhee, J.; Song, I.-W.; Kim, J.-H.; Baek, D.; Kong, Y.-Y.

10.1101/2024.03.25.586563 — neuroscience — Posted on 2024-03-27

1025 T cell receptor-centric perspective to multimodal single-cell data analysis.

Mullan, K. A.; Ha, M.; Valkiers, S.; de Vrij, N.; Ogunjimi, B.; Laukens, K.; Meysman, P.

10.1101/2023.09.27.559702 — bioinformatics — Posted on 2024-03-27

1026 Marker selection strategies for circulating tumor DNA guided by phylogenetic inference

Fu, X.; Luo, Z.; Deng, Y.; LaFramboise, W. A.; Bartlett, D.; Schwartz, R.

10.1101/2024.03.21.585352 — bioinformatics — Posted on 2024-03-27

1027 When Night Becomes Day: Artificial Light at Night Alters Insect Behavior under Semi-Natural Conditions

Levy, K.; Wegrzyn, Y.; Moaraf, S.; Barnea, A.; Ayali, A.

10.1101/2023.11.06.565762 — animal behavior and cognition — Posted on 2024-03-27

1028 Polygenic selection to a changing optimum under self-fertilisation

Hartfield, M.; Glemin, S.

10.1101/2022.11.25.517916 — evolutionary biology — Posted on 2024-03-27

1029 Puberty Blocker and Aging Impact on Testicular Cell States and Function

Murugesh, V.; Ritting, M.; Salem, S. M.; Aalam, S. M. M.; Garcia, J.; Chattha, A. J.; Zhao, Y.; Knapp, D. J.; Kalthur, G.; Granberg, C. F.; Kannan, N.

10.1101/2024.03.23.586441 — developmental biology — Posted on 2024-03-27

1030 Tonically active GABAergic neurons in the dorsal periaqueductal gray control the initiation and execution of instinctive escape

Stempel, A. V.; Evans, D. A.; Pavon Arocas, O.; Claudi, F.; Lenzi, S. C.; Kutsarova, E.; Margrie, T. W.; Branco, T.

10.1101/2023.11.03.565561 — neuroscience — Posted on 2024-03-27

1031 Parameter variability makes a major contribution to uncertainty of crop phenology simulations

Wallach, D.; Palosuo, T.; Mielenz, H.; Buis, S.; Thorburn, P.; Asseng, S.; Dumont, B.; Ferrise, R.; Gayler, S.; Ghahramani, A.; Harrison, M. T.; Hochman, Z.; Hoogenboom, G.; Huang, M.; Jing, Q.; Justes, E.; Kersebaum, K. C.; Launay, M.; Lewan, E.; Liu, K.; Luo, Q.; Mequanint, F.; Nendel, C.; Padovan, G.; Olesen, J. E.; Pullens, J. W. M.; Qian, B.; Seserman, D.-M.; Shelia, V.; Souissi, A.; Specka, X.; Wang, J.; Weber, T. K. D.; Weihermuller, L.; Seidel, S.

10.1101/2023.02.03.526931 — plant biology — Posted on 2024-03-27

1032 Universal signatures of transposable element compartmentalization across eukaryotic genomes

Gozashti, L.; Hartl, D. L.; Corbett-Detig, R.

10.1101/2023.10.17.562820 — genomics — Posted on 2024-03-27

1033 Microbiome turnover during offspring development varies with maternal care, but not moult, in a hemimetabolous insect

Cheutin, M.-C.; Boucicot, M.; Meunier, J.

10.1101/2024.03.26.586808 — microbiology — Posted on 2024-03-27

1034 Liquid phase electron microscopy of bacterial ultrastructure

Caffrey, B. J.; Pedrazo-Tardajos, A.; Liberti, E.; Gaunt, B.; Kim, J. S.; Kirkland, A. I.

10.1101/2024.02.27.580996 — microbiology — Posted on 2024-03-27

1035 Stimulus duration encoding occurs early in the moth olfactory pathway

Barta, T.; Montsempes, C.; Demondion, E.; Chatterjee, A.; Kostal, L.; Lucas, P.

10.1101/2022.07.21.501055 — neuroscience — Posted on 2024-03-27

1036 Comparison of alternative solvents for in situ extraction of hydrocarbons from the colonial green alga Botryococcus braunii race B (Showa)

Ozawa-Uyeda, T. A.; Overmans, S. J.; Bastos de Freitas, B.; Lozoya-Gloria, E.; Lauersen, K. J.

10.1101/2023.10.23.563540 — biochemistry — Posted on 2024-03-27

1037 Acquisition of Auditory Discrimination Mediated by Different Processes through Two Distinct Circuits Linked to the Lateral Striatum

Setogawa, S.; Okauchi, T.; Hu, D.; Wada, Y.; Hikishima, K.; Onoe, H.; Nishizawa, K.; Sakayori, N.; Miyawaki, H.; Kitanishi, T.; Mizuseki, K.; Cui, Y.; Kobayashi, K.

10.1101/2023.10.19.563198 — animal behavior and cognition — Posted on 2024-03-27

1038 SegmentNT: annotating the genome at single-nucleotide resolution with DNA foundation models

de Almeida, B. P.; Dalla-Torre, H.; Richard, G.; Blum, C.; Hexemer, L.; Gelard, M.; Mendoza-Revilla, J.; Pandey, P.; Laurent, S.; Lopez, M.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.

10.1101/2024.03.14.584712 — genomics — Posted on 2024-03-27

1039 Mixing selects for predation resistance in lab-evolved communities of bacterial prey and social predator Myxococcus xanthus

Saha, S.; Bhat, B.; Laloo, J. M.; Goyal, A.; Pande, S.

10.1101/2023.03.21.533597 — evolutionary biology — Posted on 2024-03-27

1040 A diversity of diversities: do complex environmental effects underpin associations between below- and aboveground taxa?

Seaton, F. M.; George, P. B.; Alison, J.; Jones, D. L.; Creer, S.; Smart, S. M.; Emmett, B.; Robinson, D. A.

10.1101/2023.06.07.544003 — ecology — Posted on 2024-03-27

1041 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease

Chen, O. Y.; Vu, D. T.; Diaz, C. S.; Bodelet, J. S.; Phan, H.; Allali, G.; Nguyen, V.-D.; Cao, H.; He, X.; Muller, Y.; Zhi, B.; Shou, H.; Zhang, H.; He, W.; Wang, X.; Munafo, M.; Trung, N. L.; Nagels, G.; Ryvlin, P.; Pantaleo, G.

10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-27

1042 The cellular representation of temperature across the somatosensory thalamus

Leva, T.; Whitmire, C.; Sauve, I.; Bokiniec, P.; Memler, C.; Horn, B.; Vestergaard, M.; Carta, M.; Poulet, J. F. A.

10.1101/2024.02.13.580167 — neuroscience — Posted on 2024-03-27

1043 Mixed clonal-aggregative multicellularity entrained by extreme salinity fluctuations in a close relative of animals

Ros-Rocher, N.; Reyes-Rivera, J.; Foroughijabbari, Y.; Combredet, C.; Larson, B. T.; Coyle, M. C.; Houtepen, E. A. T.; Vermeij, M. J. A.; King, N.; Brunet, T.

10.1101/2024.03.25.586565 — evolutionary biology — Posted on 2024-03-27

1044 Bending the course of evolution: how mutualistic interactions affect macroevolutionary dynamics of diversification in mimetic butterflies.

Chazot, N.; Pires Braga, M.; Aubier, T. G.; Llaurens, V.; Willmott, K. R.; Elias, M.

10.1101/2024.01.26.577270 — evolutionary biology — Posted on 2024-03-27

1045 Efficient differentiation of human retinal pigment epithelium cells from chemically induced pluripotent stem cells

Zhang, K.; Wang, Y.; An, Q.; Ji, H.; Wu, D.; Li, X.; Dong, X.; Zhang, C.

10.1101/2024.03.22.586212 — cell biology — Posted on 2024-03-27

1046 Extracellular vesicles promote proliferation in an animal model of regeneration

Avalos, P. N.; Wong, L. L.; Forsthoefel, D. J.

10.1101/2024.03.22.586206 — cell biology — Posted on 2024-03-27

1047 Toxin-glycolipid interactions measured by imaging surface plasmon resonance on artificial membranes predicts diffusion behavior and lipid dependence of binding to cells

Lehnert, S.; Yildiz, U. H.; Haustein, N.; Li, E.; Matysik, A.; Oglecka, K.; Rashid, R.; Boschke, E.; Liedberg, B.; Wohland, T.; Kraut, R.

10.1101/2024.03.22.586282 — cell biology — Posted on 2024-03-27

1048 Mx1-labeled pulp progenitor cells are main contributors to postnatal odontoblasts and pulp cells in murine molars

Yang, D.; Jeong, Y.; Ortinau, L.; Solidum, J.; Park, D.

10.1101/2024.03.21.586156 — cell biology — Posted on 2024-03-27

1049 Intracellular pH regulates β-catenin with low pH increasing adhesion and signaling functions

Czowski, B. J.; White, K. A.

10.1101/2024.03.22.586349 — cell biology — Posted on 2024-03-27

1050 Establishing Primary and Stable Cell Lines from Frozen Wing Biopsies for Cellular, Physiological, and Genetic Studies in Bats

Zhao, C.; Camacho, J.; Rohner, N.; Deng, F.; Morales-Sosa, P.; Bernal-Rivera, A.; Wang, Y.; Tsuchiya, D.; Javier, J.

10.1101/2024.03.22.586286 — cell biology — Posted on 2024-03-27

1051 Prevalence study of cellular capsid-specific immune responses to AAV2, 4, 5, 8, 9 and rh10 in healthy donors

Xicluna, R.; Avenel, A.; Vandamme, C.; Devaux, M.; Jaulin, N.; Couzinie, C.; Le Duff, J.; Charrier, A.; Guilbaud, M.; Adjali, O.; Gernoux, G.

10.1101/2023.12.20.570598 — immunology — Posted on 2024-03-27

1052 An Open-Access Database of Video Stimuli for Action Observation Research in Neuroimaging Settings: Psychometric Evaluation and Motion Characterization

Georgiev, C.; Legrand, T.; Mongold, S. J.; Fiedler-Valenta, M.; Guittard, F.; Bourguignon, M.

10.1101/2023.11.17.567513 — neuroscience — Posted on 2024-03-27

1053 Human stem cell derived neurons and astrocytes to detect novel auto-reactive IgG signature in immune-mediated neurological diseases

Mathias, A.; Perriot, S.; Jones, S.; Canales, M.; Bernard-Valnet, R.; Gimenez, M.; Torcida, N.; Oberholster, L.; Hottinger, A. F.; Zekeridou, A.; Theaudin, M.; Pot, C.; Du Pasquier, R.

10.1101/2024.02.26.582006 — neuroscience — Posted on 2024-03-27

1054 Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers

Lee, G.; Wong, C.; Cho, A.; West, J. J.; Crawford, A. J.; Russo, G. C.; Si, B. R.; Kim, J.; Hoffner, L.; Jang, C.; Jung, M.; Leone, R. D.; Konstantopoulos, K.; Ewald, A. J.; Wirtz, D.; Jeong, S.

10.1101/2023.05.24.541452 — cancer biology — Posted on 2024-03-26

1055 An experimental study of free flight kinematics in a miniature parasitoid wasp Trichogramma telengai

Lapina, N. A.; Farisenkov, S. E.; Shcherbakov, E. O.; Kolomenskiy, D.; Polilov, A. A.

10.1101/2024.03.21.586056 — biophysics — Posted on 2024-03-26

1056 Machine learning-guided reconstruction of cytoskeleton network from Live-cell AFM Images

Ju, H.; Skibbe, H.; Fukui, M.; Yoshimura, S. H.; Naoki, H.

10.1101/2024.03.21.584818 — biophysics — Posted on 2024-03-26

1057 The selective cargo loading and release functions of the cellular sterol transporter StarD4 are allosterically controlled by the recognition of specific PIP2 subtypes in thetargeted membranes.

Xie, H.; WEINSTEIN, H.

10.1101/2024.03.26.586881 — biophysics — Posted on 2024-03-27

1058 Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking and kinase inhibition

Narayanan, D.; Larsen, A. S. G.; Gauger, S. J.; Adafia, R.; Hammershoi, R. B.; Hamborg, L.; Bruus-Jensen, J.; Griem-Krey, N.; Gee, C. L.; Frolund, B.; Stratton, M. M.; Kuriyan, J.; Kastrup, J. S.; Langkilde, A. E.; Wellendorph, P.; Solbak, S. M. O.

10.1101/2024.03.26.586665 — biophysics — Posted on 2024-03-27

1059 Protein structural context of cancer mutations reveals molecular mechanisms and identifies novel candidate driver genes

Pino, D. C.; Badonyi, M.; Semple, C. A.; Marsh, J. A.

10.1101/2024.03.21.586131 — bioinformatics — Posted on 2024-03-26

1060 Prediction of plant complex traits via integration of multi-omics data

Wang, P.; Lehti-Shiu, M. D.; Lotreck, S.; Segura Aba, K.; Krysan, P. J.; Shiu, S.-H.

10.1101/2023.11.14.566971 — bioinformatics — Posted on 2024-03-26

1061 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening

Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.

10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-27

1062 Assessment of thermochromic phantoms for characterizing microwave ablation devices

Zia, G.; Lintz, A.; Hardin, C.; Bottiglieri, A.; Sebek, J.; Prakash, P.

10.1101/2024.03.23.584886 — bioengineering — Posted on 2024-03-26

1063 In silico mechanics of stem cells intramyocardially transplanted with a biomaterial injectate for treatment of myocardial infarction

Motchon, Y. D.; Sack, K. L.; Sirry, M. S.; Nchejane, N. J.; Abdalrahman, T.; Nagawa, J.; Kruger, M.; Pauwels, E.; Van Loo, D.; De Muynck, A.; Van Hoorebeke, L.; Davies, N. H.; Franz, T.

10.1101/2023.05.10.540185 — bioengineering — Posted on 2024-03-27

1064 Core-N-glycans are atypically abundant at the neuronal surface and regulate glutamate receptor signaling

Zhang, C.-L.; Moutoussamy, C.; Tuffery, M.; Varangot, A.; Piskorowski, R. A.; HANUS, C.

10.1101/2024.03.25.586577 — cell biology — Posted on 2024-03-27

1065 CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge

Whitelaw, J. A.; Lilla, S.; Nikolaou, S.; Tweedy, L.; Fort, L.; Paul, N. R.; Zanivan, S.; Gadegaard, N.; Insall, R. H.; Machesky, L. M.

10.1101/2024.03.26.586838 — cell biology — Posted on 2024-03-27

1066 Museomics of Carabus giant ground beetles evidences an Oligocene origin and in situ Alpine diversification

PAULI, M. T.; GAUTHIER, J.; LABEDAN, M.; BLANC, M.; BILAT, J.; TOUSSAINT, E. F. A.

10.1101/2024.03.21.586057 — zoology — Posted on 2024-03-26

1067 A cell-free workflow for detecting and characterizing RiPP recognition element-precursor peptide interactions

Wong, D. A.; Cabezas, M. D.; Daniel-Ivad, M.; Prasanna, D. V.; Fernandez, R.; Nicol, R.; Balskus, E. P.; Karim, A. S.; Jewett, M. C.

10.1101/2024.03.25.586624 — synthetic biology — Posted on 2024-03-26

1068 Hybrid Sequencing Facilitates Robust De Novo Plasmid Assembly

Hernandez, S. I.; Berezin, C.-T.; Miller, K. M.; Peccoud, S. J.; Peccoud, J.

10.1101/2024.03.25.586694 — synthetic biology — Posted on 2024-03-26

1069 Sir2 and Fun30 regulate ribosomal DNA replication timing via Mcm helicase positioning and nucleosome occupancy

Lichauco, C.; Foss, E. J.; Gatbonton-Schwager, T.; Athow, N. F.; Lofts, B.; Acob, R.; Taylor, E.; Lao, U.; Miles, s.; Bedalov, A.

10.1101/2024.03.21.586113 — genetics — Posted on 2024-03-26

1070 Megabase-scale Transgene De-Duplication to Generate a Functional Single-Copy Full-Length Human DMD Transgenic Mouse Model

Chey, Y. C. J.; Corbett, M. A.; Arudkumar, J.; Piltz, S.; Thomas, P. Q.; Adikusuma, F.

10.1101/2024.03.25.586713 — molecular biology — Posted on 2024-03-26

1071 Megabase-scale Transgene De-Duplication to Generate a Functional Single-Copy Full-Length Humanized DMD Mouse Model

Chey, Y. C.; Corbett, M. A.; Arudkumar, J.; Piltz, S.; Thomas, P. Q.; Adikusuma, F.

10.1101/2024.03.25.586713 — molecular biology — Posted on 2024-03-26

1072 Characterization of a cytokinin-binding protein locus in Mycobacterium tuberculosis

Darwin, K. H.; Yoo, J. H.; Santarossa, C.; Thomas, A. K.; Ekiert, D.

10.1101/2024.03.25.586654 — microbiology — Posted on 2024-03-26

1073 Engineering self-propelled tumor-infiltrating CAR T cells using synthetic velocity receptors

Johnston, A. C.; Alicea, G. M.; Lee, C. C.; Patel, P. V.; Hanna, E. A.; Vaz, E.; Forjaz, A.; Wan, Z.; Nair, P. R.; Lim, Y.; Chen, T.; Du, W.; Kim, D.; Nichakawade, T. D.; Rebecca, V. W.; Bonifant, C. L.; Fan, R.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.

10.1101/2023.12.13.571595 — immunology — Posted on 2024-03-26

1074 LC3-associated phagocytosis is impaired in monocyte-derived macrophages from systemic sclerosis patients

Frenger, Q.; Lucas, J.; Petitdemange, A.; Path, L.; Baldeck, N.; Depauw, S.; Giorgiutti, S.; Merlin, H.; Gong, Y.; Meyer, A.; Herber, M.; Jacquel, L.; Mertz, P.; Felten, R.; Chatelus, E.; Dieudonne, Y.; Guffroy, A.; Arnaud, L.; Poindron, V.; Gottenberg, J.-E.; Sibilia, J.; Korganow, A.-S.; Martin, T.; Gros, F.

10.1101/2024.03.21.586112 — immunology — Posted on 2024-03-26

1075 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain

Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.

10.1101/2023.10.13.562226 — neuroscience — Posted on 2024-03-26

1076 Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region

Morales-Gregorio, A.; Kurth, A. C.; Ito, J.; Kleinjohann, A.; Barthelemy, F. V.; Brochier, T.; Grün, S.; van Albada, S. J.

10.1101/2023.06.14.544966 — neuroscience — Posted on 2024-03-26

1077 Investigation of the Fasciola Cinereum, Absent in BTBR mice, and Comparison with the Hippocampal Area CA2

Lee, S. H.; Cooke, M. E.; Duan, K. Z.; Williams Avram, S.; Song, J.; Elkahloun, A. G.; McGrady, G.; NISC Comparative Sequencing Program, ; Howley, A.; Samal, B.; Young, W. S.

10.1101/2024.03.21.586108 — neuroscience — Posted on 2024-03-26

1078 Computational Exploration of Protein Structure Dynamics and RNA structural Consequences of PKD1 Missense Variants: Implications in ADPKD Pathogenesis

DEVI, C.; Ranjan, P.; Raj, S.; DAS, P.

10.1101/2024.03.21.586139 — genetics — Posted on 2024-03-26

1079 Homeotic and non-homeotic patterns in the tetrapod vertebral formula

Cerbus, R. T.; Hiratani, I.; Kawaguchi, K.

10.1101/2024.03.21.586053 — evolutionary biology — Posted on 2024-03-26

1080 Discrete Time Modeling of Stock-Recruit Relationships with Life-History Stanzas

Frank, A.-S.; Schaarschmidt, U.; Nash, R. D. M.; Subbey, S.

10.1101/2024.03.21.586068 — ecology — Posted on 2024-03-26

1081 ComPRePS: An Automated Cloud-based Image Analysis tool to democratize AI in Digital Pathology

Mimar, S.; Paul, A. S.; Lucarelli, N.; Boarder, S.; Naglah, A.; Barisoni, L.; Hodgin, J.; Rosenberg, A.; Clapp, W.; Sarder, P.

10.1101/2024.03.21.586102 — pathology — Posted on 2024-03-26

1082 Thermodynamic dissipation constrains metabolic versatility of unicellular growth

Cossetto, T.; Rodenfels, J.; Sartori, P.

10.1101/2024.03.21.585772 — biophysics — Posted on 2024-03-26

1083 Beyond IC50 - A computational dynamic model of drug resistance in enzyme inhibition treatment.

Roadnight Sheehan, J.; de Wijn, A. S.; Freire, T. S.; Friedman, R.

10.1101/2024.03.21.586067 — biophysics — Posted on 2024-03-26

1084 Exploring the accuracy of ab initio prediction methods for viral pseudoknotted RNA structures

Medeiros, V. M.; Pearl, J. M.; Carboni, M.; Er, E. M.; Zafeiri, S.

10.1101/2024.03.21.586060 — bioinformatics — Posted on 2024-03-26

1085 Escherichia coli adaptation under prolonged resource exhaustion is characterized by extreme parallelism and frequent historical contingency

Zion, S.; Katz, S.; Hershberg, R.

10.1101/2024.03.21.586114 — evolutionary biology — Posted on 2024-03-26

1086 Bone Mineralization Regulation: Using Zebrafish as a Model to Study ANKH-associated Mineralization Disorders

Wathuliyadde, N.; Willmore, K. E.; Kelly, G. M.

10.1101/2024.03.21.586098 — developmental biology — Posted on 2024-03-26

1087 An outbreak of a pathogenic canine coronavirus type 2 in captive snow leopards (Panthera uncia) in the U.S, with severe gastrointestinal signs

Olarte-Castillo, X. A.; Whittaker, G. A.

10.1101/2024.03.25.586607 — microbiology — Posted on 2024-03-26

1088 Microbiome turnover during offspring development varies with maternal care, but not moult, in a hemimetabolous insect

Cheutin, M.-C.; Boucicot, M.; Meunier, J.

10.1101/2024.03.26.586808 — microbiology — Posted on 2024-03-26

1089 The hypervirulent Group B Streptococcus HvgA adhesin promotes brain invasion through transcellular crossing of the choroid plexus

Aznar, E.; Strazielle, N.; Costa, L.; Poyart, C.; Tazi, A.; Ghersi-Egea, J.-F.; guignot, j.

10.1101/2024.03.26.586743 — microbiology — Posted on 2024-03-26

1090 Expansion of pneumococcal serotype 23F and 14 lineages with genotypic changes in capsule polysaccharide locus and virulence gene profiles post introduction of pneumococcal conjugate vaccine in Blantyre, Malawi

Cave, R.; Kalizang'oma, A.; Chaguza, C.; Mwalukomo, T. S.; Kamng'ona, A.; Brown, C.; Msefula, J.; Bonomali, F.; Nyirenda, R.; Swarthout, T. D.; Kwambana-Adams, B.; French, N.; Heyderman, R. S.

10.1101/2024.03.25.586540 — microbiology — Posted on 2024-03-26

1091 The expression of integron arrays is shaped by the translation rate of cassettes

Carvalho, A.; Hipolito, A.; Trigo da Roza, F.; Garcia-Pastor, L.; Vergara, E.; Buendia, A.; Garcia-Seco, T.; Escudero, J. A.

10.1101/2024.03.26.586746 — microbiology — Posted on 2024-03-26

1092 Genomic diversity in Paenibacillus polymyxa: Unveiling distinct species groups and functional variability

Wallner, A.; Antonielli, L.; Mesguida, O.; Rey, P.; Compant, S.

10.1101/2024.03.26.586750 — microbiology — Posted on 2024-03-26

1093 Global stress response in Pseudomonas aeruginosa upon malonate utilization

Bisht, K.; Elmassry, M. M.; al Mahmud, H.; Bhattacharjee, S.; Deonarine, A.; Black, C.; San Francisco, M.; Hamood, A. N.; Wakeman, C. A.

10.1101/2024.03.26.586813 — microbiology — Posted on 2024-03-26

1094 Isolation and characterization of a phage collection against Pseudomonas putida

Brauer, A.; Rosendahl, S.; Kangsep, A.; Lewanczyk, A. C.; Rikberg, R.; Horak, R.; Tamman, H.

10.1101/2024.03.26.586772 — microbiology — Posted on 2024-03-26

1095 Massively parallel combination screen reveals small molecule sensitization of antibiotic-resistant Gram-negative ESKAPE pathogens

Tse, M. W.; Zhu, M.; Peters, B.; Hamami, E.; Chen, J.; Davis, K. P.; Nitz, S.; Weller, J.; Warrier, T.; Hunt, D. K.; Morales, Y.; Kawate, T.; Gaulin, J. L.; Come, J. H.; Hernandez-Bird, J.; Huo, W.; Neisewander, I.; Kiessling, L. L.; Hung, D. T.; Mecsas, J.; Aldridge, B. B.; Isberg, R. R.; Blainey, P. C.

10.1101/2024.03.26.586803 — microbiology — Posted on 2024-03-26

1096 Achieving Resilience in Aging: How Mitochondrial Modulation Drives Age-associated Fluconazole Tolerance in Cryptococcus neoformans

Yoo, K.; Oliveira, N. K.; Bhattacharya, S.; Fries, B. C.

10.1101/2024.03.26.586817 — microbiology — Posted on 2024-03-26

1097 ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.

Schmid, S.; Russell, Z. R.; Yamashita, A. S.; West, M. E.; Parrish, A. G.; Walker, J.; Rudoy, D.; Yan, J. Z.; Quist, D. C.; Gessesse, B. N.; Alvinez, N.; Cimino, P. J.; Kumasaka, D. K.; Parchment, R. E.; Holland, E. C.; Szulzewsky, F.

10.1101/2024.03.13.584849 — cancer biology — Posted on 2024-03-26

1098 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.

Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.; Phillips, A.

10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-03-26

1099 MapTurns: mapping the structure, H-bonding and contexts of beta turns in proteins

Newell, N. E.

10.1101/2024.01.02.573949 — bioinformatics — Posted on 2024-03-26

1100 ExploreTurns: A web tool for the exploration and analysis of beta turns and their contexts in proteins; application to beta-bulge and Schellman loops, Asx helix caps, and other hydrogen-bonded motifs

Newell, N. E.

10.1101/2024.01.01.573820 — bioinformatics — Posted on 2024-03-26

1101 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin

Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Chen, M.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Maze, I.; Zheng, Q.

10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-26

1102 Structural Basis for Oxidized Glutathione Recognition by the Yeast Cadmium Factor 1

Soong, T. H.; Hotze, C. F.; Khandelwal, N. K.; Tomasiak, T. M.

10.1101/2024.01.31.578287 — biochemistry — Posted on 2024-03-26

1103 Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

Bendzunas, G.; Byrne, D. P.; Shrestha, S.; Daly, L. A.; Oswald, S. O.; Katiyar, S.; Venkat, A.; Yeung, W.; Eyers, C. E.; Eyers, P. A.; Kannan, N.

10.1101/2023.10.05.561145 — biochemistry — Posted on 2024-03-26

1104 Pangenomic Landscapes Shape Performances of a Synthetic Genetic Circuit Across Stutzerimonas Species

Chan, D. T. C.; Bernstein, H. C.

10.1101/2024.02.15.580380 — synthetic biology — Posted on 2024-03-26

1105 Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network

Dibyachintan, S.; Dube, A. K.; Bradley, D.; Lemieux, P.; Dionne, U.; Landry, C.

10.1101/2024.02.23.581840 — evolutionary biology — Posted on 2024-03-26

1106 Natural and age-related variation in circulating human hematopoietic stem cells

Furer, N.; Rappoport, N.; Lifshitz, A.; bercovich, A.; Ben-Kiki, O.; Danin, A.; Kedmi, M.; Shipony, Z.; Lipson, D.; Meiri, E.; Yanai, G.; Shapira, S.; Arber, N.; Berdichevsky, S.; Tavor, S.; Tyner, J.; Joshi, S. K.; Landau, D.; Ganesan, S.; Dusaj, N.; Chamely, P.; Kaushansky, N.; Chapal Ilani, N.; Shamir, R.; Tanay, A.; Shlush, L.

10.1101/2023.11.30.569167 — molecular biology — Posted on 2024-03-26

1107 A geometric parameterization for beta turns

Newell, N. E.

10.1101/2024.01.01.573818 — molecular biology — Posted on 2024-03-26

1108 Comparative pathogenesis of two lineages of Powassan virus reveals distinct clinical outcome, neuropathology, and inflammation.

Reynolds, E.; Hart, C.; Nelson, J.; Marzullo, B.; Esterly, A.; Paine, D.; Crooker, J.; Massa, P.; Thangamani, S.

10.1101/2023.08.01.551588 — microbiology — Posted on 2024-03-26

1109 The Time-Course of Food Representation in the Human Brain

Moerel, D.; Psihoyos, J.; Carlson, T. A.

10.1101/2023.06.06.543985 — neuroscience — Posted on 2024-03-26

1110 A dynamin-like protein in the human malaria parasite plays an essential role in mitochondrial homeostasis and fission during asexual blood stages

Thakur, V.; Singh, S.; Rathore, S.; Muneer, A.; Islam, M.; Datta, G.; Banday, M.; Arora, P.; Hossain, M. E.; Jain, S.; Ali, S.; Mohmmed, A.

10.1101/2024.03.25.586598 — cell biology — Posted on 2024-03-26

1111 Cryo-electron tomography reveals postsynaptic nanoblocks in excitatory synapses

Sun, R.; Allen, J. P.; Wilson, L.; Haider, M.; Alten, B.; Zhou, Z.; Wang, X.; Zhou, Q.

10.1101/2023.05.12.540562 — neuroscience — Posted on 2024-03-26

1112 Sleep need driven oscillation of glutamatergic synaptic phenotype

Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.

10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-03-26

1113 Utilizing gene co-expression networks with the rat kidney TXG-MAPr tool to enhance safety assessment, biomarker identification and human translation

Kunnen, S. J.; Callegaro, G.; Sutherland, J. J.; Trairatphisan, P.; van Kessel, H.; Wijaya, L. S.; Chung, G.; Pye, K.; Goldstein, K. M.; Teague, C. R.; Fisher, C. P.; Saez-Rodriguez, J.; Brown, C.; Elmore, S. A.; Heinz-Taheny, K. M.; Stevens, J. L.; van de Water, B.

10.1101/2023.11.03.565444 — pharmacology and toxicology — Posted on 2024-03-26

1114 Tissue-resident NK cells support survival in pancreatic cancer through promotion of cDC1-CD8T activity

Go, S.; Demetriou, C.; Valenzano, G.; Hughes, S.; Lanfredini, S.; Ferry, H.; Arbe-Barnes, E.; Sivakumar, S.; Bashford-Rogers, R.; Middleton, M. R.; Mukherjee, S.; Morton, J.; Jones, K.; O'Neill, E.

10.1101/2023.10.14.562332 — cancer biology — Posted on 2024-03-26

1115 Disrupting CD38-driven T cell dysfunction restores sensitivity to cancer immunotherapy

Revach, O.-Y.; Cicerchia, A. M.; Shorer, O.; Petrova, B.; Anderson, S.; Park, J.; Chen, L.; Mehta, A.; Wright, S. J.; McNamee, N.; Tal-Mason, A.; Cattaneo, G.; Tiwari, P.; Xie, H.; Sweere, J. M.; Cheng, L.-C.; Sigal, N.; Enrico, E.; Miljkovic, M.; Evans, S. A.; Nguyen, N.; Whidden, M. E.; Srinivasan, R.; Spitzer, M. H.; Sun, Y.; Sharova, T.; Lawless, A.; Michaud, W. A.; Rasmussen, M. Q.; Fang, J.; Palin, C.; Chen, F.; Wang, X.; Ferrone, C. R.; Lawrence, D. P.; Sullivan, R. J.; Liu, D.; Sachdeva, U. M.; Sen, D. R.; Flaherty, K. T.; Manguso, R. T.; Bod, L.; Kellis, M.; Boland, G. M.; Yizhak, K.;

10.1101/2024.02.12.579184 — cancer biology — Posted on 2024-03-26

1116 CatPred: A comprehensive framework for deep learning in vitro enzyme kinetic parameters kcat, Km and Ki

Boorla, V. S.; Maranas, C. D.

10.1101/2024.03.10.584340 — bioinformatics — Posted on 2024-03-26

1117 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening

Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.

10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-26

1118 Beyond blooms: A novel time series analysis framework predicts seasonal keystone species and sheds light on Arctic pelagic ecosystem stability

Oldenburg, E.; Kronberg, R. M.; Metfies, K.; von Appen, W.-J.; Wietz, M.; Bienhold, C.; Popa, O.; Ebenhoeh, O.

10.1101/2024.03.11.583746 — bioinformatics — Posted on 2024-03-26

1119 Jag1 Insufficiency Disrupts Neonatal T Cell Differentiation and Impairs Hepatocyte Maturation, Leading to Altered Liver Fibrosis

Masek, J.; Filipovic, I.; Van Hul, N. K.; Belicova, L.; Jirouskova, M.; Oliveira, D. V.; Frontino, A. M.; Hankeova, S.; He, J.; Turetti, F.; Iqbal, A.; Cervenka, I.; Sarnova, L.; Verboven, E.; Brabec, T.; Bjorkstrom, N. K.; Gregor, M.; Dobes, J.; Andersson, E. R.

10.1101/2022.10.24.513578 — developmental biology — Posted on 2024-03-26

1120 Rapid structural analysis of bacterial ribosomes in situ

Powell, B. M.; Brant, T. S.; Davis, J. H.; Mosalaganti, S.

10.1101/2024.03.22.586148 — cell biology — Posted on 2024-03-26

1121 SPACe (Swift Phenotypic Analysis of Cells): an open-source, single cell analysis of Cell Painting data

Stossi, F.; Singh, P. K.; Marini, M.; Safari, K.; Szafran, A. T.; Rivera-Tostado, A.; Candler, C. D.; Mancini, M. G.; Mosa, E. A.; Bolt, M. J.; Labate, D.; Mancini, M. A.

10.1101/2024.03.21.586132 — cell biology — Posted on 2024-03-26

1122 circHIPK3 nucleates IGF2BP2 and functions as a competing endogenous RNA

Okholm, T. L. H.; Kamstrup, A. B.; Nielsen, M. M.; Hollensen, A. K.; Graversgaard, M. L.; Sorensen, M. H.; Kristensen, L. S.; Vang, S.; Park, S. S.; Yeo, G. W.; Dyrskjot, L.; Kjems, J.; Pedersen, J. S.; Damgaard, C. K.

10.1101/2023.09.14.557527 — molecular biology — Posted on 2024-03-26

1123 Widespread Horizontal Gene Transfer Among Animal Viruses

Buck, C. B.; Welch, N. L.; Belford, A. K.; Varsani, A.; Pastrana, D. V.; Tisza, M. J.; Starrett, G. J.

10.1101/2024.03.25.586562 — microbiology — Posted on 2024-03-26

1124 Algorithms for a Commons Cell Atlas

Booeshaghi, A. S.; Galvez-Merchan, A.; Pachter, L.

10.1101/2024.03.23.586413 — bioinformatics — Posted on 2024-03-26

1125 Extensive long-range polycomb interactions and weak compartmentalization are hallmarks of human neuronal 3D genome

Pletenev, I. A.; Bazarevich, M.; Zagirova, D. R.; Kononkova, A. D.; Cherkasov, A. V.; Efimova, O. I.; Tiukacheva, E. A.; Morozov, K. V.; Ulianov, K. A.; Komkov, D.; Tvorogova, A. V.; Golimbet, V. E.; Kondratyev, N. V.; Razin, S. V.; Khaitovich, P.; Ulianov, S. V.; Khrameeva, E. A.

10.1101/2023.08.04.551939 — genomics — Posted on 2024-03-26

1126 Differences in polygenic associations with educational attainment between West and East Germany before and after reunification

Fraemke, D.; Willems, Y. E.; Okbay, A.; Wagner, G.; Tucker-Drob, E. M.; Harden, K. P.; Koellinger, P.; Raffington, L.

10.1101/2024.03.21.585839 — genetics — Posted on 2024-03-26

1127 m6A RNA methylation-dependent APC translation is required for local translation of beta-actin and axon development

Broix, L.; Roy, R.; Oomoto, I.; Umeshima, H.; Wang, D. O.

10.1101/2020.11.14.382556 — neuroscience — Posted on 2024-03-26

1128 The role of Kinesin-1 in neuronal dense core vesicle transport and lifespan regulation in C. elegans

Gavrilova, A.; Boström, A.; Korabel, N.; Poulin, G. B.; Fedotov, S.; Allan, V. J.

10.1101/2024.03.25.586639 — cell biology — Posted on 2024-03-26

1129 Full-length structure of the host targeted bacterial effector Bep1 reveals a novel structural domain conserved in FIC effector proteins from Bartonella

Huber, M.; Wagner, A.; Reiners, J.; Seyfert, C. E.; Sharpe, T.; Smits, S. H. J.; Schirmer, T.; Dehio, C.

10.1101/2024.03.25.586700 — microbiology — Posted on 2024-03-26

1130 Widespread Horizontal Gene Transfer Among Animal Viruses

Buck, C. B.; Welch, N. L.; Belford, A. K.; Varsani, A.; Pastrana, D. V.; Tisza, M. J.; Starrett, G. J.

10.1101/2024.03.25.586562 — microbiology — Posted on 2024-03-26

1131 Development of a ddPCR approach for the absolute quantification of soil microorganisms involved in atmospheric CO2 fixation

Le Geay, M.; Mayers, K.; Kuttim, M.; Lauga, B.; Jassey, V.

10.1101/2024.03.25.586531 — microbiology — Posted on 2024-03-26

1132 Comprehensive Invitro and Insilico Analysis of Secondary Metabolites from Datura metel: Promising Anti-Alzheimer's Therapeutics.

Sharma, M.; Jain, M.; Patil, N.; Barnwal, A.; Tayade, S.; Delta, A. K.; Kole, C.; Kaushik, P.

10.1101/2024.03.21.586063 — neuroscience — Posted on 2024-03-26

1133 Simulations reveal that beta burst detection may inappropriately characterize the beta band

Langford, Z. D.; Wilson, C. R.

10.1101/2023.12.15.571838 — neuroscience — Posted on 2024-03-26

1134 Impact of Chemical Dynamics of Commercial PURE Systems on Malachite Green Aptamer Fluorescence

Jurado, Z.; Murray, R. M.

10.1101/2024.03.15.585317 — synthetic biology — Posted on 2024-03-26

1135 CLASSIFICATION OF PROKARYOTIC DNA METHYLTRANSFERASES BY TOPOLOGY AND SEQUENCE SIMILARITY

Samokhina, M.

10.1101/2023.12.13.571470 — genomics — Posted on 2024-03-26

1136 Automatic extraction of meaning from visual number symbols detected by frequency-tagged EEG in children.

Van Rinsveld, A.; Schiltz, C.

10.1101/2024.03.21.585906 — neuroscience — Posted on 2024-03-26

1137 Sub-cone visual resolution by active, adaptive sampling in the human foveola

Witten, J. L.; Lukyanova, V.; Harmening, W. M.

10.1101/2024.03.21.586052 — neuroscience — Posted on 2024-03-26

1138 Altered empathy processing in frontotemporal dementiaA task-based fMRI study

Lindberg, O.; Li, T.-Q.; Lind, C.; Vest, S.; Alm, O.; Stiernstedt, M.; Ericson, A.; B, N.; Hansson, O.; Harper, L.; Westman, E.; Graff, C.; Tsevis, T.; Mannfolk, P.; Fischer, H.; Nilsonne, G.; Petrovic, P.; Nyberg, L.; Wahlund, L.-O.; Santillo, A.

10.1101/2024.03.21.586051 — neuroscience — Posted on 2024-03-26

1139 2P-NucTag: on-demand phototagging for molecular analysis of functionally identified cortical neurons

Shi, J.; Nutkovich, B.; Kushinsky, D.; Rao, B. Y.; Herrlinger, S. A.; Mihaila, T. S.; Malina, K. C.-K.; OToole, C. K.; Conde Paredes, M. E.; Yong, H. C.; Varol, E.; Losonczy, A.; Spiegel, I.

10.1101/2024.03.21.586118 — neuroscience — Posted on 2024-03-26

1140 A Novel 3D Imaging Approach for Quantification of GLUT4 Levels across the Intact Myocardium

Geiser, A.; Currie, S.; Al-Hasani, H.; Chadt, A.; McConnell, G.; Gould, G. W.

10.1101/2024.03.26.586764 — cell biology — Posted on 2024-03-26

1141 The role of Kinesin-1 in neuronal dense core vesicle transport and lifespan regulation in C. elegans

Gavrilova, A.; Boström, A.; Korabel, N.; Poulin, G. B.; Fedotov, S.; Allan, V. J.

10.1101/2024.03.25.586639 — cell biology — Posted on 2024-03-26

1142 A network of interacting ciliary tip proteins with opposing activities imparts slow and processive microtubule growth

Saunders, H. A. J.; van den Berg, C. M.; Hoogebeen, R.; Schweizer, D.; Stecker, K. E.; Roepman, R.; Howes, S. C.; Akhmanova, A.

10.1101/2024.03.25.586532 — cell biology — Posted on 2024-03-26

1143 Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer

Chen, K.-E.; Tillu, V. A.; Gopaldass, N.; Chowdhury, S. R.; Leneva, N.; Kovtun, O.; Ruan, J.; Guo, Q.; Ariotti, N.; Mayer, A.; Collins, B. M.

10.1101/2024.03.24.586500 — cell biology — Posted on 2024-03-26

1144 Have AI-Generated Texts from LLM Infiltrated the Realm of Scientific Writing? A Large-Scale Analysis of Preprint Platforms

Cheng, H.; Sheng, B.; Lee, A.; Chaudhary, V.; Atanasov, A. G.; Liu, N.; Qiu, Y.; Wong, T. Y.; Tham, Y.-C.; Zheng, Y.-F.

10.1101/2024.03.25.586710 — scientific communication and education — Posted on 2024-03-26

1145 Asymptotically exact fit for linear mixed model

Guan, Y.; Levy, D.

10.1101/2023.10.25.563975 — bioinformatics — Posted on 2024-03-26

1146 Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14Delta/+ mice hearts

Foo, B.; Amedei, H.; Kaur, S.; Jaawan, S.; Boshnakovska, A.; Gall, T.; de Boer, R. A.; Sillje, H. H. W.; Urlaub, H.; Rehling, P.; Lenz, C.; Lehnart, S. E.

10.1101/2024.03.21.586093 — cell biology — Posted on 2024-03-26

1147 Molecular motor tug-of-war regulates elongasome cell wall synthesis dynamics in Bacillus subtilis

Middlemiss, S.; Blandenet, M.; Roberts, D. M.; McMahon, A.; Grimshaw, J.; Edwards, J. M.; Sun, Z.; Whitley, K. D.; Blu, T.; Strahl, H.; Holden, S.

10.1101/2023.05.10.540107 — microbiology — Posted on 2024-03-26

1148 CD4+ T cells drive corneal nerve damage but are dispensable for corneal epitheliopathy development in dry eye disease

Vereertbrugghen, A.; Pizzano, M.; Cernutto, A.; Sabbione, F.; Keitelman, I. A.; Vera Aguilar, D.; Podhorzer, A.; Fuentes, F.; Corral Vazquez, C.; Guzman, M.; Giordano, M. N.; Trevani, A. S.; de Paiva, C. S.; Galletti, J. G.

10.1101/2024.03.22.586336 — immunology — Posted on 2024-03-26

1149 Traumatic injury causes selective degeneration and TDP-43 mislocalization in human iPSC-derived C9orf72-associated ALS/FTD motor neurons

Martin, E. J.; Santacruz, C.; Mitevska, A.; Jones, I. E.; Krishnan, G.; Gao, F.-B.; Finan, J. D.; Kiskinis, E.

10.1101/2024.03.21.586073 — neuroscience — Posted on 2024-03-26

1150 Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer

Lee, S. U.; Cho, Y.; Li, Y.; Li, R.; Brown, D.; McAuliffe, P. F.; LEE, A. V.; Oesterreich, S.; Zervantonakis, I.; Osmanbeyoglu, H. U.

10.1101/2024.03.21.586041 — systems biology — Posted on 2024-03-26

1151 Novel Genetically Encoded Probes for Functional Imaging of Cell Signaling by Polarization Microscopy

Miclea, P. S.; Nagy Markova, V.; Sakhi, A.; Bondar, A.; Lazar, J.

10.1101/2024.02.23.581811 — physiology — Posted on 2024-03-26

1152 A chromosome-level genome assembly of the Hispid cotton rat (Sigmodon hispidus), a model for human pathogenic virus infections

Lilue, J.; Corvelo, A.; Gomez-Garrido, J.; Yang, F.; Akagi, K.; Green, G.; Ng, B. L.; Fu, B.; Chorostecki, U.; Warner, S. C.; Marcet-Houben, M.; Keane, T.; Mullikin, J. C.; Alioto, T.; Gabaldon, T.; Hubert, B.; Symer, D. E.; Niewiesk, S.

10.1101/2024.03.21.586163 — genomics — Posted on 2024-03-26

1153 G-quadruplex formation in GCK and TM6SF2 are targets for differential DNA methylation in metabolic dysfunction-associated fatty liver disease and type II diabetes mellitus patients

Lahnsteiner, A.; Ellmer, V.; Oberlercher, A.; Lutkeviciute, Z.; Schoenauer, E.; Paulweber, B.; Aigner, E.; Risch, A.

10.1101/2024.03.21.585382 — genetics — Posted on 2024-03-26

1154 Novel assay for endangered Hong Kong grouper (Epinephelus akaara) to assess eDNA shedding, decay, and population status

Chung, A.; Kam, Y. C.; Schunter, C.

10.1101/2024.03.21.585953 — ecology — Posted on 2024-03-26

1155 CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease.

Armstrong, S. S.; Chen, D. G.; Kumar, S.; Heath, J. R.; Feinstein, M.; Greenland, J. R.; Calabrese, D. R.; Lanier, L. L.; Ley, K.; Shemesh, A.

10.1101/2024.03.22.581997 — immunology — Posted on 2024-03-26

1156 Detection and Removal of Hyper-synchronous Artifacts in Massively Parallel Spike Recordings

Oberste-Frielinghaus, J.; Morales-Gregorio, A.; Essink, S.; Kleinjohann, A.; Grun, S.; Ito, J.

10.1101/2024.01.11.575181 — neuroscience — Posted on 2024-03-26

1157 How Absence Seizures Impair Sensory Perception: Insights from Awake fMRI and Simulation Studies in Rats

Stenroos, P.; Guillemain, I.; Tesler, F.; Montigon, O.; Collomb, N.; Stupar, V.; Destexhe, A.; Coizet, V.; David, O.; Barbier, E. L.

10.1101/2023.07.26.550701 — neuroscience — Posted on 2024-03-26

1158 Unmasking Hidden Systemic Effects of Neurodegenerative Diseases: A Two-Pronged Approach to Biomarker Discovery

Anjo, S. I.; Rosado, M.; Baldeiras, I.; Gomes, A.; Pires, D.; Santa, C.; Pinto, J.; Januario, C.; Santana, I.; Verdelho, A.; Mendonca, A. d.; Castelo-Branco, M.; Manadas, B.

10.1101/2023.11.23.568435 — biochemistry — Posted on 2024-03-26

1159 Neutral genetic structuring of pathogen populations during rapid adaptation

Saubin, M.; Stoeckel, S.; Tellier, A.; Halkett, F.

10.1101/2022.10.20.512995 — evolutionary biology — Posted on 2024-03-26

1160 In silico analysis of the altered protein structure and functions caused by existing synaptic gene mutations in Indian population having neurological disorders

Divi, P. K.; Mukesh, N.; Mohapatra, S.; Kanthimath, S.; Mishra, N.; Kar, K.; Anand, B. G.; Annamneedi, A.

10.1101/2023.11.02.565337 — neuroscience — Posted on 2024-03-26

1161 A dual function of the IDA peptide in regulating cell separation and modulating plant immunity at the molecular level

Lalun, V. O.; Breiden, M.; Galindo-Trigo, S.; Smakowska-Luzan, E.; Simon, R.; Butenko, M. A.

10.1101/761346 — plant biology — Posted on 2024-03-26

1162 Chronumental: time tree estimation from very large phylogenies

Sanderson, T.

10.1101/2021.10.27.465994 — bioinformatics — Posted on 2024-03-26

1163 Mitochondrial genome variation affects humoral and cell-mediated innate immune responses and infection outcomes

Salminen, T. S.; Vesala, L.; Basikhina, Y.; Kutzer, M.; Tuomela, T.; Lucas, R.; Monteith, K.; Prakash, A.; Tietz, T.; Vale, P. F.

10.1101/2022.07.19.500574 — immunology — Posted on 2024-03-26

1164 Hippocampal-occipital connectivity reflects autobiographical memory deficits in aphantasia

Monzel, M.; Leelaarporn, P.; Lutz, T.; Schultz, J.; Brunheim, S.; Reuter, M.; McCormick, C.

10.1101/2023.08.11.552915 — neuroscience — Posted on 2024-03-26

1165 The non-mitotic role of HMMR in regulating the localization of TPX2 and the dynamics of microtubules in neurons

Chen, Y.-J.; Tseng, S.-C.; Chen, P.-T.; Hwang, E.

10.1101/2023.11.14.566966 — cell biology — Posted on 2024-03-26

1166 A high-resolution map of functional miR-181 response elements in the thymus reveals the role of coding sequence targeting and an alternative seed match

Verheyden, N. A.; Klostermann, M.; Bruggemann, M.; Steede, H. M.; Scholz, A.; Amr, S.; Lichtenthaeler, C.; Munch, C.; Schmid, T.; Zarnack, K.; Krueger, A.

10.1101/2023.09.08.556730 — immunology — Posted on 2024-03-26

1167 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design

Trygoniaris, D.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.

10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-03-26

1168 Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

Ma, X.; Meng, L.; Zhang, Y.; Xu, T.; Zhou, X.; Qian, M.; Yang, Z.; Han, X.

10.1101/2023.10.02.560590 — microbiology — Posted on 2024-03-25

1169 Nonlinear feedback modulation contributes to the optimization of flexible decision-making

Zhou, Y.; Wu, X.

10.1101/2023.07.15.549136 — neuroscience — Posted on 2024-03-25

1170 Acoustic inspired brain-to-sentence decoder for logosyllabic language

Feng, C.; Cao, L.; Wu, D.; Zhang, E.; Wang, T.; Jiang, X.; Zhou, C.; Chen, J.; Wu, H.; Lin, S.; Hou, Q.; Yang, J.; Lin, C.-T.; Zhu, J.; Sawan, M.; Zhang, Y.

10.1101/2023.11.05.562313 — neuroscience — Posted on 2024-03-26

1171 Arabidopsis transcriptome responses to low water potential using high throughput plate assays

Gonzalez, S.; Swift, J.; Yaaran, A.; Xu, J.; Miller, C.; Illouz-Eliaz, N.; Nery, J. R.; Zait, Y.; Busch, W.; Ecker, J. R.

10.1101/2022.11.25.517922 — plant biology — Posted on 2024-03-25

1172 Pharmacogenomic synthetic lethal screens reveal hidden vulnerabilities and new therapeutic approaches for treatment of NF1-associated tumors

Williams, K. B.; Larsson, A. T.; Keller, B. J.; Chaney, K. E.; Williams, R. L.; Jubenville, T. A.; Bhunia, M. M.; Draper, G. M.; Rathe, S. K.; Moertel, C. L.; Ratner, N.; Largaespada, D. A.

10.1101/2024.03.25.585959 — cancer biology — Posted on 2024-03-25

1173 Generative Adversarial Networks Accurately Reconstruct Pan-Cancer Histology from Pathologic, Genomic, and Radiographic Latent Features

Howard, F. M.; Hieromnimon, H.; Ramesh, S.; Dolezal, J.; Kochanny, S.; Zhang, Q.; Feiger, B.; Peterson, J.; Fan, C.; Perou, C.; Vickery, J. M.; Sullivan, M.; Cole, K.; Khramtsova, G.; Pearson, A. T.

10.1101/2024.03.22.586306 — cancer biology — Posted on 2024-03-25

1174 Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response

Hofer, S.; Frasch, L.; Putzker, K.; Lewis, J.; Sakhteman, A.; The, M.; Bayer, F. P.; Muller, J.; Hamood, F.; Kuster, B.

10.1101/2024.03.22.586243 — cancer biology — Posted on 2024-03-25

1175 Universal Cold RNA Phase Transitions

Rissone, P.; Severino, A.; Pastor del Campo, I.; Ritort Farran, F.

10.1101/2024.03.22.586224 — biophysics — Posted on 2024-03-25

1176 Deep learning to decode sites of RNA translation in normal and cancerous tissues

Clauwaert, J.; McVey, Z.; Gupta, R.; Menschaert, G.; Prensner, J.

10.1101/2024.03.21.586110 — bioinformatics — Posted on 2024-03-25

1177 Influenza sequence validation and annotation using VADR

Calhoun, V. C.; Hatcher, E. L.; Yankie, L.; Nawrocki, E. P.

10.1101/2024.03.21.585980 — bioinformatics — Posted on 2024-03-25

1178 PEPerMINT: Peptide Abundance Imputation in Mass Spectrometry-based Proteomics using Graph Neural Networks

Pietz, T.; Gupta, S.; Schlaffner, C. N.; Ahmed, S.; Steen, H.; Renard, B. Y.; Baum, K.

10.1101/2024.03.23.586248 — bioinformatics — Posted on 2024-03-25

1179 GeneSqueeze: A Novel Lossless, Reference-Free Compression Algorithm for FASTQ/A Files

Nazari, F.; Patel, S.; LaRocca, M.; Czarny, R.; Schena, G.; Murray, E. K.

10.1101/2024.03.21.586111 — bioinformatics — Posted on 2024-03-25

1180 Analysis of the limited M. tuberculosis accessory genome reveals potential pitfalls of pan-genome analysis approaches

Marin, M. G.; Wippel, C.; Quinones-Olvera, N.; Behruznia, M.; Jeffrey, B. M.; Harris, M.; Mann, B. C.; Rosenthal, A.; Jacobson, K. R.; Warren, R. M.; Li, H.; Meehan, C. J.; Farhat, M. R.

10.1101/2024.03.21.586149 — bioinformatics — Posted on 2024-03-25

1181 MOTL: enhancing multi-omics matrix factorization with transfer learning

Hirst, D.; Terezol, M.; Cantini, L.; Villoutreix, P.; Vignes, M.; Baudot, A.

10.1101/2024.03.22.586210 — bioinformatics — Posted on 2024-03-25

1182 Reference-informed prediction of alternative splicing and splicing-altering mutations from sequences

Xu, C.; Bao, S.; Chen, H.; Jiang, T.; Zhang, C.

10.1101/2024.03.22.586363 — bioinformatics — Posted on 2024-03-25

1183 Robust diagnosis of infectious disease, autoimmunity and cancer from the paratope networks of adaptive immune receptors

Xu, Z.; Ismanto, H. S.; Saputri, D. S.; Haruna, S.; Sun, G.; Wilamowski, J.; Teraguchi, S.; Sengupta, A.; Standley, D. M.

10.1101/2023.11.28.569125 — bioinformatics — Posted on 2024-03-25

1184 Assessment of thermochromic phantoms for characterizing microwave ablation devices

Zia, G.; Lintz, A.; Hardin, C.; Bottiglieri, A.; Sebek, J.; Prakash, P.

10.1101/2024.03.23.584886 — bioengineering — Posted on 2024-03-25

1185 Self-organization of vascularized skeletal muscle from bovine embryonic stem cells

Sanaki-Matsumiya, M.; Villava, C.; Rappez, L.; Haase, K.; Wu, J.; Ebisuya, M.

10.1101/2024.03.22.586252 — bioengineering — Posted on 2024-03-25

1186 Functional metagenomics reveals an alternative, broad-specificity pathway for metabolism of carbohydrates in human gut commensal bacteria

Nasseri, S. A.; Lazarski, A. C.; Lemmer, I. L.; Zhang, C. Y.; Brencher, E.; Chen, H.-M.; Sim, L.; Betschart, L.; Worral, L. J.; Strynadka, N. C. J.; Withers, S. G.

10.1101/2024.03.25.586180 — biochemistry — Posted on 2024-03-25

1187 Flight performance, activity and behaviour of breeding pied flycatchers in the wild, revealed with accelerometers and machine learning

Yu, H.; Liang, S.; Muijres, F. T.; te Lindert, J. S.; de Knegt, H. J.; Hedenstrom, A.; Lamers, K. P.; Henningsson, P.

10.1101/2024.03.21.586090 — animal behavior and cognition — Posted on 2024-03-25

1188 A multi-tissue de novo transcriptome assembly and relative gene expression of the vulnerable freshwater salmonid Thymallus ligericus

Secci-Petretto, G.; Weiss, S. J.; Gomes-dos-Santos, A.; Persat, H.; Machado, A. M.; Vasconcelos, I.; Castro, L. F.; Froufe, E.

10.1101/2024.03.21.586089 — genomics — Posted on 2024-03-25

1189 SERBP1 interacts with PARP1 and is present in PARylation-dependent protein complexes regulating splicing, cell division, and ribosome biogenesis

Breunig, K.; Lei, X.; Montalbano, M.; Guardia, G.; Ostadrahimi, S.; Alers, V.; Kosti, A.; Chiou, J.; Klein, N.; Vinarov, C.; Wang, L.; Li, M.; Song, W.; Kraus, W. L. O.; Libich, D. S.; Tiziani, S.; Weintraub, S. T.; Galante, P. A. F.; Penalva, L. O.

10.1101/2024.03.22.586270 — genomics — Posted on 2024-03-25

1190 Unveiling the genetic blueprint of a desert scorpion: A chromosome-level genome of Hadrurus arizonensis provides the first reference for Parvorder Iurida

Bryant, M. J.; Coello, A. M.; Glendening, A. M.; Hilliman, S. A.; Jara, C. F.; Pring, S. S.; Rivera, A. R.; Santiago Membreno, J.; Nigro, L.; Pauloski, N.; Graham, M. R.; King, T.; Jockusch, E. L.; O'Neill, R. J.; Wegrzyn, J. L.; Santibanez-Lopez, C. E.; Webster, C. N.

10.1101/2024.03.22.586284 — genomics — Posted on 2024-03-25

1191 Unexpectedly low recombination rates and presence of hotspots in termite genomes

Everitt, T.; Ronneburg, T.; Elsner, D.; Olsson, A.; Liu, Y.; Larva, T.; Korb, J.; Webster, M. T.

10.1101/2024.03.22.586269 — genomics — Posted on 2024-03-25

1192 Global coral genomic vulnerability explains recent reef losses

Selmoni, O.; Cleves, P. A.; Exposito-Alonso, M.

10.1101/2024.03.25.586253 — evolutionary biology — Posted on 2024-03-25

1193 Characterization of Genome-wide Phylogenetic Conflict Uncovers Evolutionary Modes of Carnivorous Fungi

Zhang, W.; Fan, Y.; Deng, W.; Chen, Y.; Wang, S.; Kang, S.; Steenwyk, J. L.; Xiang, M.; Liu, X.

10.1101/2024.03.21.586083 — evolutionary biology — Posted on 2024-03-25

1194 The refinement paradox and cumulative cultural evolution: collective improvement in knowledge favors conformity, blind copying and hyper-credulity

Miu, E.; Rendell, L.; Bowles, S.; Boyd, R.; Cownden, D.; Enquist, M.; Eriksson, K.; Feldman, M. W.; Lillicrap, T.; McElreath, R.; Murray, S.; Ounsley, J.; Lala, K. N.

10.1101/2024.03.22.586239 — evolutionary biology — Posted on 2024-03-25

1195 Reassembly of a tropical rainforest ecosystem: A new chronosequence in the Ecuadorian Choco tested with the recovery of tree attributes

Escobar, S.; Newell, F. L.; Endara, M.-J.; Guevara-Andino, J. E.; Landim, A. R.; Neuschulz, E. L.; Nusser, R.; Müller, J.; Pedersen, K. M.; Schleuning, M.; Tremlett, C. J.; Villa-Galaviz, E.; Schaefer, H. M.; Donoso, D. A.; Blüthgen, N.

10.1101/2024.03.21.586145 — ecology — Posted on 2024-03-25

1196 Effectiveness of fixation methods for wholemount immunohistochemistry across cellular compartments in chick embryos

Echeverria, C. V.; Leathers, T. A.; Rogers, C. D.

10.1101/2024.03.23.586361 — developmental biology — Posted on 2024-03-25

1197 Gag proteins encoded by endogenous retroviruses are required for zebrafish development

Chang, N.-C.; Wells, J. N.; Wang, A. Y.; Schofield, P.; Huang, Y.-C.; Truong, V. H.; Simoes-Costa, M.; Feschotte, C.

10.1101/2024.03.25.586437 — developmental biology — Posted on 2024-03-25

1198 Identification and characterization of the de novo methyltransferases for eukaryotic N6-methyladenine (6mA)

Cheng, T.; Zhang, J.; Li, H.; Diao, J.; Zhang, W.; Niu, J.; Kataoka, K.; Gao, S.

10.1101/2024.03.25.586193 — molecular biology — Posted on 2024-03-25

1199 Preeclampsia in mice carrying fetuses with APOL1 risk variants

Yoshida, T.; Latt, K. Z.; Shrivastav, S.; Lu, H.; Reidy, K. J.; Charlton, J. R.; Zhao, Y.; Winkler, C. A.; Reznik, S. E.; Rosenberg, A. Z.; Kopp, J. B.

10.1101/2024.03.20.586039 — molecular biology — Posted on 2024-03-25

1200 Parabrachial Calca neurons mediate second-order conditioning

Palmiter, R.; Park, S.; Zhu, A.; Cao, F.

10.1101/2024.03.21.586150 — neuroscience — Posted on 2024-03-25

1201 Connectomic reconstruction of a cortical column

Sievers, M.; Motta, A.; Schmidt, M.; Yener, Y.; Loomba, S.; Song, K.; Bruett, J.; Helmstaedter, M.

10.1101/2024.03.22.586254 — neuroscience — Posted on 2024-03-25

1202 Circadian control in the timing of critical periods during Drosophila larval neuronal development.

Doran, S.; Bradlaugh, A. A.; Corke, J.; Baines, R. A.

10.1101/2024.03.21.586088 — neuroscience — Posted on 2024-03-25

1203 Attentional modulation of secondary somatosensory and visual thalamus of mice

Petty, G.; Bruno, R. M.

10.1101/2024.03.22.586242 — neuroscience — Posted on 2024-03-25

1204 Seeing the piles of the velvet bending under our finger sliding over a tactile stimulator improves the perception of the fabric

Mouchnino, L.; Camillieri, B.; Faucheu, J.; Juganaru, M.; Moinon, A.; Blouin, J.; Bueno, M.-A.

10.1101/2024.03.22.586227 — neuroscience — Posted on 2024-03-25

1205 Specific and comprehensive genetic targeting reveals brain-wide distribution and synaptic input patterns of GABAergic axo-axonic interneurons

Raudales, R.; Kim, G.; Kelly, S. M.; Hatfield, J.; Guan, W.; Zhao, S.; Paul, A.; Qian, Y.; Li, B.; Huang, Z. J.

10.1101/2023.11.07.566059 — neuroscience — Posted on 2024-03-25

1206 Unifying sparse coding, predictive coding, and divisive normalization

Lian, Y.; Burkitt, A. N.

10.1101/2023.06.08.544285 — neuroscience — Posted on 2024-03-25

1207 Through the lens of causal inference: Decisions and pitfalls of covariate selection

Chen, G.; Cai, Z.; Taylor, P. A.

10.1101/2024.01.11.575211 — neuroscience — Posted on 2024-03-25

1208 Modeling Molecular Mechanisms of Pirfenidone Interaction with Kinases

Wijewardhane, P.; Wells, A.; Muhoberac, M.; Leung, K. P.; Chopra, G.

10.1101/2024.03.22.586235 — systems biology — Posted on 2024-03-25

1209 Unveiling lipid chemodiversity in root exudates: A comprehensive characterizaton of the exudate metabo-lipidome in Tall Wheatgrass

Couvillion, S. P.; Yang, I.; Eder, J.; Bell, S.; Hofmockel, K.

10.1101/2024.03.22.586263 — plant biology — Posted on 2024-03-25

1210 Unraveling the Role of 12-cis-Oxo-Phytodienoic Acid in the Wound Response of Arabidopsis thaliana: Insights from Transcriptomic and Complementation Studies

Mekkaoui, K.; Baral, R.; Smith, F.; Klein, M.; Feussner, I.; Hause, B.

10.1101/2024.03.22.586262 — plant biology — Posted on 2024-03-25

1211 A comparative study of plant phenotyping workflows based on three-dimensional reconstruction from multi-view images

Someno, D.; Noshita, K.

10.1101/2024.03.21.586185 — plant biology — Posted on 2024-03-25

1212 An atlas of Brachypodium distachyon lateral root development

de Jesus Vieira Teixeira, C.; Bellande, K.; van der Schuren, A.; O'Connor, D.; Hardtke, C. S.; Vermeer, J.

10.1101/2024.03.25.586236 — plant biology — Posted on 2024-03-25

1213 Suboptimal refeeding compensates stunting in a mouse model of juvenile malnutrition

Thoumas, J.-L.; Cavaroc, A.; Sery, D.; Leulier, F.; De Vadder, F.

10.1101/2024.03.25.586077 — physiology — Posted on 2024-03-25

1214 No evidence that shrinking and shapeshifting meaningfully affect how birds respond to warming and cooling

Tabh, J. K. R.; Persson, E.; Correia, M.; O Cuiv, C.; Thoral, E.; Nord, A.

10.1101/2024.03.22.586255 — physiology — Posted on 2024-03-25

1215 Transcriptional landscape of the dorsal raphe serotonin neurons rendering stress resiliency

Andoh, C.; Otani, S.; Noguchi, T.; Hagiwara, M.; Nishitani, N.; Kawai, H.; Fukui, Y.; Koda, M.; Morishita, H.; Nomura, K.; Oki, M.; Hori, H.; Shirakawa, H.; Kaneko, S.; Nagayasu, K.

10.1101/2024.03.21.586199 — pharmacology and toxicology — Posted on 2024-03-25

1216 Spatial proteomics and transcriptomics of placenta accreta spectrum

Bartels, H. C.; Hameed, S.; Young, C.; Nabhan, M.; Downy, P.; Curran, K. M.; McCormack, J.; Fabre, A.; Kolch, W.; Zhernovkov, V.; Brennan, D. J.

10.1101/2024.03.21.585167 — bioinformatics — Posted on 2024-03-25

1217 Marine biofilms: cyanobacteria factories for the global oceans

cheng, Z.; Shun, Y.; Yingdong, L.; Jiawei, C.; Tong, W.; Ruojun, W.; Kun, Z.; Aifang, C.; Weiduo, H.; Hongbin, L.; Kurt O., K.; Wataru, I.; Pei-Yuan, Q.

10.1101/2024.03.25.586614 — microbiology — Posted on 2024-03-25

1218 Infection of human organoids supports an intestinal niche for Chlamydia trachomatis

Hovhannisyan, P.; Stelzner, K.; Keicher, M.; Paprotka, K.; Neyazi, M.; Pauzuolis, M.; Ali, W. M.; Rajeeve, K.; Bartfeld, S.; Rudel, T.

10.1101/2024.03.25.586552 — microbiology — Posted on 2024-03-25

1219 Cortical evidence accumulation for perceptual experience occurs irrespective of reports

Stockart, F.; Msheik, R.; Robin, A.; Jurkovicova, L.; Goueytes, D.; Rouy, M.; Marecek, R.; Hoffmann, D.; Mudrik, L.; Roman, R.; Brazdil, M.; Minotti, L.; Kahane, P.; Pereira, M.; Faivre, N.

10.1101/2024.03.20.585198 — neuroscience — Posted on 2024-03-25

1220 Synaptic Theory of Working Memory for Serial Order

Mongillo, G.; Tsodyks, M.

10.1101/2024.01.11.575157 — neuroscience — Posted on 2024-03-25

1221 Microvascular structure variability explains variance in fMRI functional connectivity

Gaudreault, F.; Desjardins, M.

10.1101/2024.03.22.585979 — neuroscience — Posted on 2024-03-25

1222 System and transcript dynamics of cells infected with severe acute respiratory syndrome virus 2 (SARS-CoV-2)

Silva, J. M. F.; Oteo, J. A.; Garay, C. P.; Elena, S. F.

10.1101/2024.03.25.586528 — systems biology — Posted on 2024-03-25

1223 Root foraging response to gradients of calcium and magnesium, essential bivalent cations with low mobility in the soil

Skalova, H.; Pankova, K.; Stiblikova, P.; Krivohlavy, F.; Hadincova, V.; Tylova, E.; Herben, T.

10.1101/2024.03.20.584955 — plant biology — Posted on 2024-03-25

1224 Neuroprotective Effects of Bioactive Molecules Derived from Tobacco as Potential Therapeutic Candidates for Alzheimer Disease

Liao, C.; Li, M.; Li, Z.; Wang, M.; Peng, Q.; Zhu, Z.; Wang, H.-H.; Guan, Y.

10.1101/2024.03.20.585935 — pharmacology and toxicology — Posted on 2024-03-25

1225 Spatial partitioning of a microbial population enhances collective enzymatic defence

Verdon, N.; Popescu, O.; Titmuss, S.; Allen, R. J.

10.1101/2024.03.20.585867 — biophysics — Posted on 2024-03-25

1226 PreTSA: computationally efficient modeling of temporal and spatial gene expression patterns

Zhuang, H.; Ji, Z.

10.1101/2024.03.20.585926 — bioinformatics — Posted on 2024-03-25

1227 VaccineDesigner: A Web-based Tool for Streamlined Epitope-based Vaccine Design

Trygoniaris, D. G.; Anna, K.; Paraskeva, A.; Dhusku, E.; Tzimagiorgis, G.; Yiangou, M.; Kotzamanidis, C.; Malousi, A.

10.1101/2024.03.20.585850 — bioinformatics — Posted on 2024-03-25

1228 Allograft and Autograft Anterior Cruciate Ligament Reconstructions Exhibit a Similar Biological Response to Cyclic Loading

Paschall, L. N.; Tsai, A.; Tabdanov, E.; Dhawan, A.; Szczesny, S.

10.1101/2024.03.20.585695 — bioengineering — Posted on 2024-03-25

1229 Unlocking the Genetic Potential of Solanum bulbocastanum (SB22, Selection 22): A Valuable Resource for Enhancing Disease Resistance in Commercial Potato Cultivars

Sathuvalli, V.; Shanmugavel, S.; Vining, K. J.; Talbot, S. C.; Brown, C.

10.1101/2024.03.20.586016 — genomics — Posted on 2024-03-25

1230 Relationship between weapon size and six key behavioural and physiological traits in males of the European earwig

Blackwell, S. E. M.; Pasquier, L.; Dupont, S.; devers, S.; Lecureuil, C.; Meunier, J.

10.1101/2024.03.20.585871 — evolutionary biology — Posted on 2024-03-25

1231 Blue appendages and temperature acclimation increase survival during acute heat stress in the upside-down jellyfish, Cassiopea xamachana

Maloney, M. E.; Buckley, K.; Strader, M. E.

10.1101/2024.03.20.586014 — ecology — Posted on 2024-03-25

1232 Pseudo-pac site sequences used by phage P22 in generalized transduction of Salmonella

Maier, J.; Gin, C.; Callahan, B.; Sheriff, E. K.; Duerkop, B. A.; Kleiner, M.

10.1101/2024.03.25.586692 — microbiology — Posted on 2024-03-25

1233 DPR-MEDIATED H2O2 RESISTANCE CONTRIBUTES TO STREPTOCOCCI SURVIVAL IN A CYSTIC FIBROSIS AIRWAY MODEL SYSTEM

Rogers, R.; Kestheley, C.; Jean-Pierre, F.; El Hafi, B.; O'Toole, G.

10.1101/2024.03.25.586644 — microbiology — Posted on 2024-03-25

1234 Peptides from non-immune proteins target infections through antimicrobial and immunomodulatory properties

Torres, M. D. T.; Cesaro, A.; de la Fuente, C.

10.1101/2024.03.25.586636 — microbiology — Posted on 2024-03-25

1235 Profiling trace organic chemical biotransformation genes, enzymes and associated bacteria in microbial model communities

Cao, L.; Garcia, S. L.; Wurzbacher, C.

10.1101/2024.03.25.586518 — microbiology — Posted on 2024-03-25

1236 Defensive fungal symbiosis on insect hindlegs

Nishino, T.; Mukai, H.; Moriyama, M.; Hosokawa, T.; Tanahashi, M.; Tachikawa, S.; Nikoh, N.; Koga, R.; Fukatsu, T.

10.1101/2024.03.25.586038 — microbiology — Posted on 2024-03-25

1237 Discovery and heterologous expression of functional 4-O-dimethylallyl-L-tyrosine synthases from lichen-forming fungi.

Iacovelli, R.; He, S.; Sokolova, N.; Lokhorst, I.; Borg, M.; Fodran, P.; Haslinger, K.

10.1101/2024.03.23.586307 — microbiology — Posted on 2024-03-25

1238 Host cell-specific metabolism of linoleic acid controls Toxoplasma gondii growth in cell culture

Hryckowian, N. D.; Zinda, C.; Park, S. C.; Kelty, M. T.; Knoll, L. J.

10.1101/2024.03.22.586332 — microbiology — Posted on 2024-03-25

1239 Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

Warren, C.; Barbachano-Guerrero, A.; DuMont, V.; Stabell, A.; Dirasantha, O.; Yang, Q.; Sawyer, S. L.

10.1101/2023.11.13.566830 — microbiology — Posted on 2024-03-25

1240 Functional Diversity of Memory CD8 T Cells is Spatiotemporally Imprinted

Reina-Campos, M.; Monell, A.; Ferry, A.; Luna, V.; Cheung, K.; Galletti, G.; Scharping, N. E.; Takehara, K.; Quon, S.; Boland, B.; Lin, Y. H.; Wong, W. H.; Indralingam, C. S.; Yeo, G. W.; Chang, J. T.; Heeg, M.; Goldrath, A. W.

10.1101/2024.03.20.585130 — immunology — Posted on 2024-03-25

1241 Human airway macrophages are metabolically reprogrammed by IFN-γ resulting in glycolysis dependent functional plasticity.

Cox, D. J.; Connolly, S. A.; Maoldomhnaigh, C. O.; Brugman, A. A.; Thomas, O. S.; Duffin, E.; O'Connell, F.; Phelan, J. J.; Gogan, K. M.; Gleeson, L. E.; Basdeo, S. A.; Keane, J.

10.1101/2024.03.20.585747 — immunology — Posted on 2024-03-25

1242 HIV envelope trimers and gp120 as immunogens to induce broadly neutralizing antibodies in cows

Altman, P. X.; Parren, M.; Sang, H.; Ozorowski, G.; Lee, W.-H.; Smider, V. V.; Wilson, I. A.; Ward, A. B.; Mwangi, W.; Burton, D. R.; Sok, D.

10.1101/2024.03.20.585065 — immunology — Posted on 2024-03-25

1243 Data science and its future in large neuroscience collaborations.

Schottdorf, M.; Yu, G.; Walker, E. Y.

10.1101/2024.03.20.585936 — neuroscience — Posted on 2024-03-25

1244 Synaptic weight dynamics underlying systems consolidation of a memory

Bhasin, B. J.; Raymond, J. L.; Goldman, M. S.

10.1101/2024.03.20.586036 — neuroscience — Posted on 2024-03-25

1245 Adaptation optimizes sensory encoding of future stimuli

Mao, J.; Rothkopf, C. A.; Stocker, A. A.

10.1101/2024.03.20.585768 — neuroscience — Posted on 2024-03-25

1246 Phylotranscriptomics provides a treasure trove of flood tolerance mechanisms in the Cardamineae tribe

van Veen, H.; Mueller, J. T.; Bartylla, M. M.; Akman, M.; Sasidharan, R.; Mustroph, A.

10.1101/2024.03.20.585870 — plant biology — Posted on 2024-03-25

1247 A circadian transcriptional sub-network and EARLY FLOWERING 3 control timing of senescence and grain nutrition in bread wheat

Buckley, C. R.; Boyte, J. M.; Albiston, R. L.; Hyles, J.; Beasley, J. T.; Johnson, A. A.; Trevaskis, B.; Fournier-Level, A.; Haydon, M. J.

10.1101/2024.02.19.580927 — plant biology — Posted on 2024-03-25

1248 Systematic Evaluation of High-Throughput PBK Modelling Strategies for the Prediction of Intravenous and Oral Pharmacokinetics in Humans

Geci, R.; Gadaleta, D.; Garcia de Lomana, M.; Ortega-Vallbona, R.; Colombo, E.; Serrano-Candelas, E.; Paini, A.; Kuepfer, L.; Schaller, S.

10.1101/2024.03.20.585001 — pharmacology and toxicology — Posted on 2024-03-25

1249 Chronic hypertension and perfusion deficits conjointly affect disease outcome after tPA treatment in a rodent model of thromboembolic stroke

Franx, B. A. A.; Tiebosch, I. A. C. W.; van der Toorn, A.; Dijkhuizen, R. M.

10.1101/2024.03.20.585876 — pathology — Posted on 2024-03-25

1250 How do we respond to the next SARS CoV epidemic/pandemic? A bioinformatics approach with the promise of preventing or reducing the severity of future SARS CoV related pandemics

Geoffrey A S, B.; Gracia, J.

10.1101/2024.03.22.586249 — bioinformatics — Posted on 2024-03-25

1251 A Histomorphometric and Computational Investigation of the Stabilizing Role of Pectinate Ligaments in the Aqueous Outflow Pathway

Safa, B. N.; Fraticelli Guzman, N. S.; Li, G.; Stamer, W. D.; Feola, A. J.; Ethier, C. R.

10.1101/2023.10.17.562754 — bioengineering — Posted on 2024-03-25

1252 μ-Opioid receptor transcriptional variants in the murine forebrain and spinal cord

Chroszcz, M.; Hajto, J.; Misiolek, K.; Szumiec, L.; Ziemianska, M.; Radlicka-Borysewska, A.; Borczyk, M.; Zieba, M.; Golda, S.; Siwiec, M.; Ziolkowska, B.; Piechota, M.; Korostynski, M.; Parkitna, J. M. R.

10.1101/2024.03.20.585849 — genomics — Posted on 2024-03-25

1253 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2024-03-25

1254 Emergent time scales of epistasis in protein evolution

Di Bari, L.; Bisardi, M.; Cotogno, S.; Weigt, M.; Zamponi, F.

10.1101/2024.03.14.585034 — evolutionary biology — Posted on 2024-03-25

1255 Genetic causes and genomic consequences of breakdown of distyly in Linum trigynum

Gutierrez-Valencia, J.; Zervakis, P.-I.; Postel, Z.; Fracassetti, M.; Losvik, A.; Mehrabi, S.; Bunikis, I.; Soler, L.; Hughes, P. W.; Desamore, A.; Laenen, B.; Abdelaziz, M.; Vinnere Pettersson, O.; Arroyo, J.; Slotte, T.

10.1101/2023.11.16.567348 — evolutionary biology — Posted on 2024-03-25

1256 Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Singh, A.; Rigon, M.; Caldeira, M.; Faccenda, D.; Xia, D.; Lopez-Tremoleda, J.; Falah Hassan Al-Khateeb, Z.; Guo, T.; Abeti, R.; Giunti, P.; Campanella, M.

10.1101/2024.03.18.585507 — cell biology — Posted on 2024-03-25

1257 A continuum of CD4+ T cell 'help' defines Memory B cell fate

Pritchard, G. H.; Krishnamurty, A. T.; Rodda, L.; McDougal, C.; Shehata, L.; Pepper, M.

10.1101/564351 — immunology — Posted on 2024-03-25

1258 A septo-hypothalamic-medullary circuit directs stress-induced analgesia

Shah, D. P.; Sharma, P. R.; Agarwal, R.; Barik, A.

10.1101/2023.01.30.526171 — neuroscience — Posted on 2024-03-25

1259 Gene expression plasticity of the mammalian brain circadian clock in response to photoperiod

Cox, O. H.; Giannoni-Guzman, M. A.; Cartailler, J.-P.; Cottam, M. A.; McMahon, D. G.

10.1101/2024.02.16.580759 — neuroscience — Posted on 2024-03-25

1260 Systemic inflammation triggers long-lasting neuroinflammation and accelerates neurodegeneration in a rat model of Parkinson's disease overexpressing human alpha-synuclein

Massaro Cenere, M.; Tiberi, M.; Paldino, E.; D'Addario, S. L.; Federici, M.; Giacomet, C.; Cutuli, D.; Matteocci, A.; Cossa, F.; Zarrilli, B.; Casadei, N.; Ledonne, A.; Petrosini, L.; Berretta, N.; Fusco, F. R.; Chiurchiu, V.; Mercuri, N. B.

10.1101/2024.01.30.577912 — neuroscience — Posted on 2024-03-25

1261 An ultra-high-throughput method for measuring biomolecular activities

Tu, B.; Sundar, V.; Esvelt, K.

10.1101/2022.03.09.483646 — synthetic biology — Posted on 2024-03-25

1262 UniFed: A unified deep learning framework for segmentation of partially labelled, distributed neuroimaging data

Dinsdale, N. K.; Jenkinson, M.; Namburete, A. I.

10.1101/2024.02.05.578912 — neuroscience — Posted on 2024-03-25

1263 Unrestricted versus Regulated Open Data Governance: A Bibliometric Comparison of SARS-CoV-2 Nucleotide Sequence Databases

Sheehan, N. P.; Leonelli, S.; Botta, F.

10.1101/2023.05.13.540634 — genetics — Posted on 2024-03-25

1264 Sugar assimilation underlying dietary evolution of Neotropical bats

Camacho, J.; Bernal-Rivera, A.; Pena, V.; Morales-Sosa, P.; Robb, S.; Russell, J.; Yi, K.; Tsuchiya, D.; Wang, Y.; Murillo-Garcia, O. E.; Rohner, N.

10.1101/2023.07.02.547432 — evolutionary biology — Posted on 2024-03-25

1265 BCL11b interacts with RNA and proteins involved in RNA processing and developmental diseases

Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; Kashif, M.; WALLET, C.; DAOUAD, F.; Loustau, T.; Van Lint, C.; SCHWARTZ, C.; ROHR, O.

10.1101/2020.11.05.369959 — developmental biology — Posted on 2024-03-25

1266 Oligonucleotide Library Assisted Sequence Mining Reveals Promoter Sequences With Distinct Temporal Expression Dynamics For Applications In Curvibacter SP. AEP1-3

Mager, M.; Becker, L.; Schulten, N.; Fraune, S.; Axmann, I. M.

10.1101/2024.03.24.586450 — synthetic biology — Posted on 2024-03-25

1267 METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma

Thombare, K.; Vaid, R.; Pucci, P.; Mendez, A.; Burgos-Panadero, R.; Ayyalusamy, R.; Rehan, A. A.; Baig, M. H.; Nale, S. D.; Bartenhagen, C.; Dong, J. j.; Fischer, M.; Turner, S. D.; Mondal, T.

10.1101/2023.10.06.561194 — cancer biology — Posted on 2024-03-25

1268 Simulating the cellular context in synthetic datasets for cryo-electron tomography

Martinez-Sanchez, A.; Lamm, L.; Jasnin, M.; Phelippeau, H.

10.1101/2023.05.26.542411 — bioinformatics — Posted on 2024-03-25

1269 Structural characterization of ligand binding and pH-specific enzymatic activity of mouse Acidic Mammalian Chitinase

Diaz, R. E.; Ecker, A. K.; Correy, G. J.; Asthana, P.; Young, I. D.; Faust, B.; Thompson, M. C.; Seiple, I. B.; Van Dyken, S. J.; Locksley, R. M.; Fraser, J. S.

10.1101/2023.06.03.542675 — biochemistry — Posted on 2024-03-25

1270 Diverse Database and Machine Learning Model to narrow the generalization gap in RNA structure prediction

Rouskn, S.; de Lajarte, A.; Martin Des Taillades, Y.; Kalicki, C.; Fuchs, F.; Aruda, J.; Salazar, D.; Allan, M.; LEsperance-Kerckhoff, C.; Kashi, A.; Jossinet, F.

10.1101/2024.01.24.577093 — biochemistry — Posted on 2024-03-25

1271 Partitioning variance in a signaling trade-off under sexual selection reveals among-individual covariance in trait allocation

Reichert, M. S.; de la Hera, I.; Moiron, M.

10.1101/2022.10.10.511667 — animal behavior and cognition — Posted on 2024-03-25

1272 Large-scale investigation of species-specific orphan genes in the human gut microbiome elucidates their evolutionary origins

Vakirlis, N.; Kupczok, A.

10.1101/2023.07.17.549306 — evolutionary biology — Posted on 2024-03-25

1273 Jag1 Insufficiency Disrupts Neonatal T Cell Differentiation and Impairs Hepatocyte Maturation, Leading to Altered Liver Fibrosis

10.1101/2022.10.24.513578 — developmental biology — Posted on 2024-03-25

1274 A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

Maher, S. P.; Bakowski, M. A.; Vantaux, A.; Flannery, E. L.; Andolina, C.; Gupta, M.; Antonova-Koch, Y.; Argomaniz, M.; Monica, C.-M.; Brice, C.; Chao, A. T.; Chatterjee, A. K.; Cheng, W. T.; Chuenchob, E.; Cooper, C. A.; Karissa, C.; Galinski, M. R.; Harupa-Chung, A.; Ji, H.; Joseph, S. B.; Lenz, T.; Lonardi, S.; Matheson, J.; Mikolajczak, S. A.; Timothy, M.; Orban, A.; Padin-Irizarry, V.; Pan, K.; Peneau, J.; Prudhomme, J.; Roesch, C.; Ruberto, A. A.; Sabnis, S. S.; Saney, C. L.; Sattabongkot, J.; Sereshki, S.; Suriyakan, S.; Ubalee, R.; Wang, Y.; Wasisakun, P.; Yin, J.; Popovici, J.; McNama

10.1101/2023.01.31.526483 — cell biology — Posted on 2024-03-25

1275 Homeostasis of a representational map in the neocortex

Noda, T.; Kienle, E.; Eppler, J.-B.; Aschauer, D. F.; Kaschube, M.; Loewenstein, Y.; Rumpel, S.

10.1101/2023.06.13.544358 — neuroscience — Posted on 2024-03-25

1276 Development of an ultrafast pulsed ponderomotive phase plate for cryo-electron tomography

Du, D. X.; Bartnik, A. C.; Duncan, C. J. R.; Choudhry, U.; Tabachnik, T.; Sallah, C.; Najafi, E.; Yang, D.-S.; Maxson, J. M.; Fitzpatrick, A. W. P.

10.1101/2024.03.20.585981 — biophysics — Posted on 2024-03-25

1277 The neuron as a temporal electroacoustic medium

Meseguer Rico, F.; Ramiro-Manzano, F.

10.1101/2023.12.20.572553 — biophysics — Posted on 2024-03-25

1278 MassDash: A Web-based Dashboard for Data-Independent Acquisition Mass Spectrometry Visualization

Sing, J. C.; Charkow, J.; AlHigaylan, M.; Horecka, I.; Xu, L.; Roest, H. L.

10.1101/2024.01.15.575772 — bioinformatics — Posted on 2024-03-25

1279 Harnessing Agent-Based Modeling in CellAgentChat to Unravel Cell-Cell Interactions from Single-Cell Data

Raghavan, V.; Li, Y.; Ding, J.

10.1101/2023.08.23.554489 — bioinformatics — Posted on 2024-03-25

1280 Animal group size variation in a minimal attraction-repulsion agent-based model

Eikelboom, J. A. J.; Doelman, A.; Van Langevelde, F.; De Knegt, H. J.

10.1101/2024.03.20.585938 — ecology — Posted on 2024-03-25

1281 Social network centrality predicts dietary decisions in a wild bird population

McMahon, K.; Marples, N. M.; Spurgin, L. G.; Rowland, H. M.; Sheldon, B. S.; Firth, J. A.

10.1101/2023.08.25.554636 — ecology — Posted on 2024-03-25

1282 Nucleoid-associated proteins shape the global protein occupancy and transcriptional landscape of a clinical isolate of Vibrio cholerae

Rakibova, Y.; Dunham, D. T.; Seed, K. D.; Freddolino, L.

10.1101/2023.12.30.573743 — microbiology — Posted on 2024-03-25

1283 Strategies for Genetic Manipulation of the Halotolerant Black Yeast H. werneckii: Ectopic DNA Integration and Marker-free CRISPR/Cas9 Transformation

Hernandez-Rodriguez, Y.; Bullard, A. M.; Busch, R. J.; Vargas-Muniz, J. M.

10.1101/2024.03.06.583723 — microbiology — Posted on 2024-03-25

1284 Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection

Simmons, S. R.; Herring, S. E.; Tchalla, E. Y. I.; Lenhard, A. P.; Bhalla, M.; Bou Ghanem, E. N.

10.1101/2024.01.08.574741 — immunology — Posted on 2024-03-25

1285 Selective deletion of interleukin-1 alpha in microglia regulates neuronal activity and neurorepair processes after experimental ischemic stroke.

Lemarchand, E.; Grayston, A.; Wong, R.; Rogers, M.; Ouvrier, B.; Llewellyn, B.; Webb, F.; Lenart, N.; Denes, A.; Brough, D.; Allan, S. M.; Bix, G.; Pinteaux, E.

10.1101/2024.02.16.580635 — neuroscience — Posted on 2024-03-25

1286 RBM39 degrader invigorates natural killer cells to eradicate neuroblastoma despite cancer cell plasticity

Singh, S.; Fang, J.; Jin, H.; Van de Velde, L.-A.; Wu, Q.; Cortes, A.; Morton, C.; Woolard, M.; Quarni, W.; Steele, J.; Connelly, J.; He, L.; Thorne, R.; Turner, G.; Confer, T.; Johnson, M.; Caufield, W.; Freeman, B.; Lockey, T.; Pruett-Miller, S.; Wang, R.; Davidoff, A.; Thomas, P.; Yang, J.

10.1101/2024.03.21.586157 — cancer biology — Posted on 2024-03-25

1287 Noise Reduction and Localization Accuracy in a Mobile Magnetoencephalography System

Bardouille, T.; Smith, V.; Vajda, E.; Leslie, C. D.; Holmes, N.

10.1101/2024.03.20.585911 — biophysics — Posted on 2024-03-25

1288 PHARAOH: A collaborative crowdsourcing platform for PHenotyping And Regional Analysis Of Histology

Faust, K.; Chen, M. L.; Zadeh, P. B.; Oreopoulos, D. G.; Leon, A. J.; Kamski-Hennekam, E.; Mikhail, M.; Duan, X.; Duan, X.; Liu, M.; Ahangari, N.; Cotau, R.; Castillo, V. F.; Nikzad, N.; Sugden, R. J.; Murphy, P.; Done, S.; Aljohani, S. S.; Echelard, P.; Jakate, K.; Alwelaie, Y.; Alyousef, M. J.; Alsafwani, N. S.; Alrumeh, A. S.; Saleeb, R.; Richer, M.; Marins, L. V.; Yousef, G. M.; Diamandis, P.

10.1101/2024.03.20.585977 — bioinformatics — Posted on 2024-03-25

1289 A method for focused ultrasound (FUS) neuromodulation with simultaneous electroencephalogram recordings in awake, head-fixed mice with temporal lobe epilepsy

Cornelssen, C.; Brown, B.; Finlinson, E.; Blair, S.; Senthilkumar, S.; Kubanek, J.; Wilcox, K. S.

10.1101/2024.03.20.585988 — bioengineering — Posted on 2024-03-25

1290 A human-aware control paradigm for human-robot interactions, a simulation study

Razavian, R. S.

10.1101/2024.03.20.585749 — bioengineering — Posted on 2024-03-25

1291 Molybdate delays sulphide formation in the sediment and transfer to the bulk liquid in a model shrimp pond

Torun, F.; Hostins, B.; De Schryver, P.; Boon, N.; De Vrieze, J.

10.1101/2023.11.16.567380 — bioengineering — Posted on 2024-03-25

1292 Mitochondrial stress in GABAergic neurons non-cell autonomously regulates organismal health and aging

Rathor, L.; Curry, S.; Park, Y.; McElroy, T.; Robles, B.; Yi, S.; Chen, W.-W.; Min, K.; Xiao, R.; Lee, M. H.; Han, S. M.

10.1101/2024.03.20.585932 — genetics — Posted on 2024-03-25

1293 Extended culture of 2D gastruloids to model human mesoderm development

Chen, B.; Khan, H.; Yu, Z.; Yao, L.; Freeburne, E.; Jo, K.; Johnson, C.; Heemskerk, I.

10.1101/2024.03.21.585753 — developmental biology — Posted on 2024-03-25

1294 Paraneoplastic renal dysfunction in fly cancer models driven by inflammatory activation of stem cells

Kwok, S. H.; Liu, Y.; Bilder, D.; Kim, J.

10.1101/2024.03.21.586173 — developmental biology — Posted on 2024-03-25

1295 Molecular stratification of human fetal vaginal epithelium by spatial transcriptome analysis

Zhao, g.; Ye, Z.; Jiang, P.; Zhu, Q.; Pei, Z.; Hu, Y.

10.1101/2024.03.20.585995 — cell biology — Posted on 2024-03-25

1296 Sensory integration of food availability and population density during the diapause exit decision involves insulin-like signaling in Caenorhabditis elegans

Zhang, M. G.; Seyedolmohadesin, M.; Mercado, S. H.; Park, H.; Finnen, N.; Schroeder, F. C.; Venkatachalam, V.; Sternberg, P. W.

10.1101/2024.03.20.586022 — neuroscience — Posted on 2024-03-25

1297 Shrinkage estimation of gene interaction networks in single-cell RNA sequencing data

Vo, D. H. T.; Thorne, T.

10.1101/2024.03.20.585951 — systems biology — Posted on 2024-03-25

1298 Effects of nano urea on growth and gene expression of Arabidopsis thaliana in hydroponics

JANGID, N.; MARIK, D.; VERMA, D.; DEY, A.; SHEKHAWAT, R. S.; PATEL, D.; YADAV, P.; SANKHALA, K.; SADHUKHAN, A.

10.1101/2024.03.20.585664 — plant biology — Posted on 2024-03-25

1299 A torpor-like state (TLS) in mice slows blood epigenetic aging and prolongs healthspan

Jayne, L.; Lavin-Peter, A.; Roessler, J.; Tyshkovskiy, A.; Antoszewski, M.; Ren, E.; Markovski, A.; Sun, S.; Yao, H.; Sankaran, V. G.; Gladyshev, V. N.; Brooke, R. T.; Horvath, S.; Griffith, E. C.; Hrvatin, S.

10.1101/2024.03.20.585828 — physiology — Posted on 2024-03-25

1300 Design, synthesis and pharmacological characterization of the first photoswitchable small-molecule agonist for the Atypical Chemokine Receptor 3

Berenger, S.; Adamska, J. M.; Deflorian, F.; de Graaf, C.; Palmer, C. B.; Szpakowska, M.; Chevigne, A.; de Esch, I. J. P.; Zarzycka, B.; Vischer, H. F.; Wijtmans, M.; Leurs, R.

10.1101/2024.03.20.585914 — pharmacology and toxicology — Posted on 2024-03-25

1301 Machine learning predicts lifespan and underlying causes of death in aging C. elegans

Kern, C.; Manescu, P.; Cuffaru, M.; Au, C.; Zhange, A.; Wang, H.; Gilliat, A. F.; Ezcurra, M.; Gems, D.

10.1101/2024.03.20.585803 — genetics — Posted on 2024-03-25

1302 A high-throughput zebrafish screen identifies novel candidate treatments for Kaposiform Lymphangiomatosis (KLA)

Bassi, I.; Jabali, A.; Farag, N.; Egozi, S.; Moshe, N.; Leichner, G. S.; Geva, P.; Levin, L.; Barzilai, A.; Avivi, C.; Long, J.; Otterstrom, J. J.; Paran, Y.; Barr, H.; Yaniv, K.; Greenberger, S.

10.1101/2024.03.21.586124 — developmental biology — Posted on 2024-03-25

1303 Compartmentalized localization of perinuclear proteins within germ granules in C. elegans

Guang, S.; Chen, X.

10.1101/2024.03.25.586584 — cell biology — Posted on 2024-03-25

1304 Effects of Age and Noise Exposure History on Auditory Nerve Response Amplitudes: A Systematic Review, Study, and Meta-Analysis

Dias, J. W.; McClaskey, C. M.; Alvey, A. P.; Lawson, A.; Matthews, L. J.; Dubno, J. R.; Harris, K. C.

10.1101/2024.03.20.585882 — neuroscience — Posted on 2024-03-25

1305 Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways

Quirion, L.; Robert, A.; Boulais, J.; Huang, S.; Bernal Astrain, G.; Strakhova, R.; Jo, C. H.; Kherdjemil, Y.; Thibault, M.-P.; Faubert, D.; Kmita, M.; Baskin, J. M.; Gingras, A.-C.; Smith, M. J.; Cote, J.-F.

10.1101/2023.03.01.530598 — molecular biology — Posted on 2024-03-25

1306 sgRNA constraints and genetic limitations for efficient Cas9 genome editing to generate knock-outs

Haussmann, I. U.; Dix, T. C.; McQuarrie, D. W.; Dezi, V.; Hans, A. I.; Arnold, R.; Soller, M.

10.1101/2022.12.15.520550 — molecular biology — Posted on 2024-03-25

1307 Decoding the Cognitive map: Learning place cells and remapping

Pettersen, M. B.; Schoyen, V. S.; Malthe-Sorenssen, A.; Lepperod, M. E.

10.1101/2024.03.14.585049 — neuroscience — Posted on 2024-03-25

1308 Detecting rhythmic spiking through the power spectra of point process model residuals

Cox, K. M.; Kase, D.; Znati, T.; Turner, R. S.

10.1101/2023.09.08.556120 — neuroscience — Posted on 2024-03-25

1309 Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

Gonschorek, D.; Goldin, M. A.; Oesterle, J.; Schwerd-Kleine, T.; Arlinghaus, R.; Zhao, Z.; Schubert, T.; Marre, O.; Euler, T.

10.1101/2023.12.23.572742 — neuroscience — Posted on 2024-03-25

1310 scATAnno: Automated Cell Type Annotation for single-cell ATAC Sequencing Data

Jiang, Y.; Hu, Z.; Lynch, A. W.; Jiang, J.; Zhu, A.; Zhang, Y.; Xie, Y.; Li, R.; Zhou, N.; Meyer, C. A.; Cejas, P.; Brown, M.; Long, H. W.; Qiu, X.

10.1101/2023.06.01.543296 — bioinformatics — Posted on 2024-03-25

1311 Allele frequency dynamics under sex-biased demography and sex-specific inheritance in a pedigreed jay population

Driscoll, R. M. H.; Beaudry, F. E. G.; Cosgrove, E. J.; Fitzpatrick, J. W.; Schoech, S. J.; Chen, N.

10.1101/2021.10.28.466320 — evolutionary biology — Posted on 2024-03-25

1312 Conway-Bromage-Lyndon (CBL): an exact, dynamic representation of k-mer sets

Martayan, I.; Cazaux, B.; Limasset, A.; Marchet, C.

10.1101/2024.01.29.577700 — bioinformatics — Posted on 2024-03-25

1313 Exploring Liquid-Liquid Phase Separation in the Organization of Golgi Matrix Proteins

Mendes, L. F. S.; Oliveira, C. G.; Costa Filho, A. J.; Kava, E.

10.1101/2023.07.21.550027 — biochemistry — Posted on 2024-03-25

1314 Understanding systems level metabolic adaptation resulting from osmotic stress

Tremblay, A.; Bekiaris, P. S.; Klamt, S.; Mahadevan, R.

10.1101/2024.03.19.585265 — microbiology — Posted on 2024-03-25

1315 MSK1 absence hinders BDNF-dependent striatal neurodevelopment and leads to schizophrenia symptoms

Varela-Andres, N.; Cebrian-Leon, A.; Hernandez-del Cano, C.; Fernandez-del Campo, I. S.; Garcia-Losada, S.; Martin-Avila, N.; Arevalo, J. C.; Merchan, M.; Sanchez-Martin, M. A.; Deogracias, R.

10.1101/2024.01.23.576945 — neuroscience — Posted on 2024-03-25

1316 Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

Zhang, X.; Das, T.; Chao, T. F.; Trinh, V.; Carmen, R.; Ling, J. P.; Kalab, P.; Hayes, L. R.

10.1101/2023.08.01.551528 — cell biology — Posted on 2024-03-25

1317 Acute multi-level response to defective de novo chromatin assembly in S-phase

10.1101/2024.03.22.586291 — cell biology — Posted on 2024-03-25

1318 A multicellular developmental program in a close animal relative

Olivetta, M.; Bhickta, C.; Chiaruttini, N.; Burns, J. A.; Dudin, O.

10.1101/2024.03.25.586530 — developmental biology — Posted on 2024-03-25

1319 Evidence of neocortex-like primitive laminar pallium in avian embryo & its organization by microRNA-19b

Sindhu, S. K.; Mishra, A.; Udaykumar, N.; Sen, J.

10.1101/2020.06.21.163980 — developmental biology — Posted on 2024-03-25

1320 Highly efficient tamoxifen-inducible Cre recombination in embryonic, larval and adult zebrafish

Bakunaite, E.; Gecaite, E.; Lazutka, J.; Balciunas, D.

10.1101/2024.03.21.586128 — developmental biology — Posted on 2024-03-25

1321 Chainsaw: protein domain segmentation with fullyconvolutional neural networks

Wells, J.; Hawkins-Hooker, A.; Bordin, N.; Sillitoe, I.; Paige, B.; Orengo, C.

10.1101/2023.07.19.549732 — molecular biology — Posted on 2024-03-25

1322 Exploring Motor Network Connectivity in State-Dependent Transcranial Magnetic Stimulation: A Proof-of-Concept Study

Marzetti, L.; Basti, A.; Guidotti, R.; Baldassarre, A.; Metsomaa, J.; Zrenner, C.; D'Andrea, A.; Makkinayeri, S.; Pieramico, G.; Ilmoniemi, R. J.; Ziemann, U.; Romani, G. L.; Pizzella, V.

10.1101/2023.06.29.547027 — neuroscience — Posted on 2024-03-25

1323 On the mechanism for winter stem pressure build-up in walnut trees

Bozonnet, C.; Saudreau, M.; Badel, E.; Charrier, G.; Ameglio, T.

10.1101/2023.12.21.572762 — plant biology — Posted on 2024-03-25

1324 HyperPRI: A Dataset of Hyperspectral Images for Underground Plant Root Study

Chang, S. J.; Chowdhry, R.; Song, Y.; Mejia, T.; Hampton, A.; Kucharski, S.; Sazzad, T.; Zhang, Y.; Koppal, S. J.; Wilson, C. H.; Gerber, S.; Tillman, B.; Resende, M. F.; Hammond, W. M.; Zare, A.

10.1101/2023.09.29.559614 — plant biology — Posted on 2024-03-25

1325 GFPrint™: A MACHINE LEARNING TOOL FOR TRANSFORMING GENETIC DATA INTO CLINICAL INSIGHTS

Sanz-Martin, G.; Migliore, D. P.; Gomez del Campo, P.; del Castillo-Izquierdo, J.; Dominguez, J. M.

10.1101/2024.03.08.584090 — bioinformatics — Posted on 2024-03-25

1326 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics

Mc Cartney, A. M.; Formenti, G.; Mouton, A.; De Panis, D.; Marins, L. S.; Leitao, H. G.; Diedericks, G.; Kirangwa, J.; Morselli, M.; Salces, J.; Escudero, N.; Iannucci, A.; Natali, C.; Svardal, H.; Fernandez, R.; De Pooter, T.; Joris, G.; Strazisar, M.; Wood, J.; Herron, K. E.; Seehausen, O.; Watts, P. C.; Shaw, F.; Davey, R. P.; Minotto, A.; Fernandez Gonzalez, J. M.; Bohne, A.; Alegria, C.; Alioto, T.; Alves, P. C.; Amorim, I. R.; Aury, J.-M.; Backstrom, N.; Baldrian, P.; Ballarin, L.; Baltrunaite, L.; Barta, E.; BedHom, B.; Belser, C.; Bergsten, J.; Bertrand, L.; Bilandija, H.; Binzer-Panch

10.1101/2023.09.25.559365 — genomics — Posted on 2024-03-25

1327 Reproductive modes of polyploid Ludwigia grandiflora subsp. hexapetala in western Europe: the effects of a late-acting self-incompatibility system and its absence on genetic diversity within populations

stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.

10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-03-25

1328 Solution to what? Global review of nature-based solutions, urban challenges, and outcomes

Li, M.; Remme, R. P.; van Bodegom, P. M.; van Oudenhoven, A. P. E.

10.1101/2023.12.07.570577 — ecology — Posted on 2024-03-25

1329 Within-host viral growth and immune response rates predict FMDV transmission dynamics for African Buffalo

Macdonald, J. C.; Gulbudak, H.; Beechler, B.; Gorsich, E.; Gubbins, S.; Perez-Martin, E.; Jolles, A.

10.1101/2022.12.02.518883 — ecology — Posted on 2024-03-25

1330 Intra-leaf modeling of Cannabis leaflet shape produces leaf models that predict genetic and developmental identities

Balant, M.; Garnatje, T.; Vitales, D.; Hidalgo, O.; Chitwood, D. H.

10.1101/2023.08.15.553356 — developmental biology — Posted on 2024-03-25

1331 Mind the blank: behavioral, experiential, and physiological signatures of absent-mindedness

Musat, E. M.; Corcoran, A. W.; Belloli, L.; Naccache, L.; Andrillon, T.

10.1101/2024.02.11.579845 — neuroscience — Posted on 2024-03-25

1332 Aβ-driven nuclear pore complex dysfunction alters activation of necroptosis proteins in a mouse model of Alzheimer's Disease

Bansal, V. A.; Tan, J. M.; Soon, H. R.; Zainolabidin, N. B.; Saito, T.; Ch'ng, T. H.

10.1101/2024.01.08.574293 — neuroscience — Posted on 2024-03-25

1333 Aberrant methylation and expression of TNXB promotes chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling

Chen, J.; Zeng, Q.; Wang, X.; Xu, R.; Wang, W.; Huang, Y.; Sun, Q.; Yuan, W.; Wang, P.; Chen, D.; Tong, P.; Jin, H.

10.1101/2023.12.11.570472 — molecular biology — Posted on 2024-03-25

1334 Resource or slot model in visual working memory: Are they different?

Hojjati, F.; Motahharynia, A.; Adibi, A.; Adibi, I.; Sanayei, M.

10.1101/2024.02.08.579494 — neuroscience — Posted on 2024-03-25

1335 Transcription Factor HNF4A is Involved in Breast Cancer Recurrence

Valiya Veettil, R.; Eyal Altman, N.; Hashkes, R.; Rubin, E.

10.1101/2024.03.23.586428 — bioinformatics — Posted on 2024-03-25

1336 Deep Divergences Among Inconspicuously Colored Clades of Epipedobates Poison Frogs

Lopez-Hervas, K.; Santos, J. C.; Ron, S. R.; Betancourth-Cundar, M.; Cannatella, D. C.; Tarvin, R. D.

10.1101/2023.06.29.547117 — evolutionary biology — Posted on 2024-03-24

1337 SECE: accurate identification of spatial domain by incorporating global spatial proximity and local expression proximity

Yu, Y.; He, Y.; Xie, Z.

10.1101/2023.12.26.573377 — bioinformatics — Posted on 2024-03-24

1338 Differential gene expression and chromatin accessibility in the medial prefrontal cortex associated with individual differences in rat behavioral models of opioid use disorder

Liu, S. X.; Muelken, P.; Maxim, Z. L.; Ramakrishnan, A.; Estill, M. S.; LeSage, M. G.; Smethells, J. R.; Shen, L.; Tran, P. V.; Harris, A. C.; Gewirtz, J. C.

10.1101/2024.02.29.582799 — neuroscience — Posted on 2024-03-24

1339 Infralimbic parvalbumin neural activity facilitates cued threat avoidance

Ho, Y.-Y.; Yang, Q.; Boddu, P.; Bulkin, D. A.; Warden, M. R.

10.1101/2023.08.18.553864 — neuroscience — Posted on 2024-03-24

1340 Cryo-EM structure of the tetra-phosphorylated R-domain in Ycf1 reveals key interactions for transport regulation

de Carvalho, R. S. A.; Rasel, M. S. I.; Khandelwal, N. K.; Tomasiak, T. M.

10.1101/2024.03.06.583773 — biochemistry — Posted on 2024-03-24

1341 Design of a sequestration-based network with tunable pulsing dynamics

Nakamura, E.; Cuba Samaniego, C.; Blanchini, F.; Giordano, G.; Franco, E.

10.1101/2024.03.24.586474 — synthetic biology — Posted on 2024-03-24

1342 Conversion of natural cytokine receptors into orthogonal synthetic biosensors

Edelstein, H. I.; Cosio, A.; Ezekiel, M. L.; Corcoran, W. K.; Morris, A. H.; Leonard, J. N.

10.1101/2024.03.23.586421 — synthetic biology — Posted on 2024-03-24

1343 Oligonucleotide Library Assisted Sequence Mining Reveals Promoter Sequences With Distinct Temporal Expression Dynamics For Applications In Curvibacter SP. AEP1-3

Mager, M.; Becker, L.; Schulten, N.; Fraune, S.; Axmann, I. M.

10.1101/2024.03.24.586450 — synthetic biology — Posted on 2024-03-24

1344 Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

Berezovsky, A. D.; Nuga, O.; Datta, I.; Bergman, K.; Sabedot, T.; Gurdziel, K.; Irtenkauf, S.; Hasselbach, L.; Meng, Y.; Mueller, C.; Petricoin, E.; Brown, S.; Purandare, N.; Aras, S.; Mikkelsen, T.; Poisson, L.; Noushmehr, H.; Ruden, D. M.; deCarvalho, A.

10.1101/2024.03.14.585115 — cancer biology — Posted on 2024-03-24

1345 Modeling Allosteric Mechanisms of Eukaryotic Type II Topoisomerases

Evoli, S.; Kariyawasam, N. L.; Nitiss, K. C.; Nitiss, J. L.; Wereszczynski, J.

10.1101/2023.08.02.551689 — biophysics — Posted on 2024-03-24

1346 PACS allows comprehensive dissection of multiple factors governing chromatin accessibility from snATAC-seq data

Miao, Z.; Wang, J.; Park, K.; Kuang, D.; Kim, J.

10.1101/2023.07.30.551108 — bioinformatics — Posted on 2024-03-24

1347 Eukaryotic Elongation Factor 2 Kinase EFK-1/eEF2K promotes starvation resistance by preventing oxidative damage in C. elegans

Yan, J.; Bhanshali, F.; Shuzenji, C.; Mendenhall, T. T.; Cheng, X.; Bai, P.; Diwan, G.; Seraj, D.; Meyer, J. N.; Sorensen, P. H.; Hartman, J. H.; Taubert, S.

10.1101/2024.03.20.585993 — genetics — Posted on 2024-03-24

1348 Unveiling the control of N and P on DOM fate in a Mediterranean coastal environment

Dignan, C.; Lenoble, V.; Santinelli, C.; Bachi, G.; Dang, D. H.; Garcia, N.; Misson, B.

10.1101/2024.03.20.585141 — ecology — Posted on 2024-03-24

1349 Spatial Transcriptomic Analysis Identifies Epithelium-Macrophage Crosstalk in Endometriotic Lesions

Burns, G. W.; Fu, Z.; Vegter, E. L.; Madaj, Z. B.; Greaves, E.; Flores, I.; Fazleabas, A. T.

10.1101/2024.03.23.586434 — molecular biology — Posted on 2024-03-24

1350 CMG helicase disassembly is essential and driven by two pathways in budding yeast

Labib, K.; Deegan, T. D.; Polo Rivera, C.

10.1101/2024.03.24.586448 — molecular biology — Posted on 2024-03-24

1351 MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION

Gharsallah, C.; Lecoeur, H.; Varet, H.; Legendre, R.; Sismeiro, O.; Coppee, J.-Y.; Proux, C.; Prina, E.; Spaeth, G. F.

10.1101/2024.03.24.586456 — microbiology — Posted on 2024-03-24

1352 Circular RNA Obelisk-S.s is highly abundant in Streptococcus sanguinis SK36

Maddamsetti, R.; You, L.

10.1101/2024.03.24.586467 — microbiology — Posted on 2024-03-24

1353 Elucidating Microbial Iron Corrosion Mechanisms with a Hydrogenase-Deficient Strain of Desulfovibrio vulgaris

Wang, D.; Ueki, T.; Ma, P.; Xu, D.; Lovley, D. R.

10.1101/2024.03.24.586472 — microbiology — Posted on 2024-03-24

1354 Translocation of YopJ family effector proteins through the VirB/VirD4 T4SS of Bartonella

Fromm, K.; Ortelli, M.; Boegli, A.; Dehio, C.

10.1101/2024.03.23.586424 — microbiology — Posted on 2024-03-24

1355 Defining the constituents and functions of a lipid-based jumbo phage compartment

Mozumdar, D.; Fossati, A.; Stevenson, E.; Guan, J.; Nieweglowska, E. S.; Rao, S.; Agard, D.; Swaney, D. L.; Bondy-Denomy, J.

10.1101/2024.03.24.586471 — microbiology — Posted on 2024-03-24

1356 Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor

Oshima, H. S.; Ogawa, A.; Sano, F. K.; Akasaka, H.; Kawakami, T.; Okamoto, H. H.; Iwama, A.; Nagiri, C.; Wei, F.-Y.; Shihoya, W.; Nureki, O.

10.1101/2024.03.23.586386 — biophysics — Posted on 2024-03-24

1357 A human commons cell atlas reveals cell type specificity for OAS1 isoforms

Galvez-Merchan, A.; Booeshaghi, A. S.; Pachter, L.

10.1101/2024.03.23.586412 — bioinformatics — Posted on 2024-03-24

1358 Engineering of highly active and diverse nuclease enzymes by combining machine learning and ultra-high-throughput screening

Thomas, N.; Belanger, D.; Xu, C.; Lee, H.; Hirano, K.; Iwai, K.; Polic, V.; Nyberg, K. D.; Hoff, K.; Frenz, L.; Emrich, C. A.; Kim, J. W.; Chavarha, M.; Ramanan, A.; Agresti, J. J.; Colwell, L. J.

10.1101/2024.03.21.585615 — bioinformatics — Posted on 2024-03-24

1359 Sulfoquinovosyl diacylglycerol is required for dimerization of the Rhodobacter sphaeroides RC-LH1 core complex

Martin, E. C.; Bowie, A. G.; Reid, T. W.; Hunter, C. N.; Hitchcock, A.; Swainsbury, D. J. K.

10.1101/2024.03.24.586425 — biochemistry — Posted on 2024-03-24

1360 Let-7i-5p regulates osteogenic differentiation of bone marrow mesenchymal stem cells induced by psoralen by targeting CKIP-1

Chen, M.; Zhou, S.; Huang, S.; Luo, H.; Zhang, X.; Liu, G.; Li, H.; Liu, B.; Yan, D.

10.1101/2024.03.20.585715 — genetics — Posted on 2024-03-24

1361 Hypervariable DOM properties in coastal NW Mediterranean Sea -Evidences of strong human influences and potential consequences for the heterotrophic base of planktonic food webs

Dignan, C.; Lenoble, V.; Garcia, N.; Oursel, B.; Cindric, A.-M.; Misson, B.

10.1101/2024.03.20.585671 — ecology — Posted on 2024-03-24

1362 Signal-independent activation reveals two-component regulatory networks

Claverie, C.; Coppolino, F.; Mazzuoli, M.-V.; Guyonnet, C.; Jacquemet, E.; Legendre, R.; Sismeiro, O.; De Gaetano, G. V.; Teti, G.; Trieu-Cuot, P.; Tazi, A.; Beninati, C.; Firon, A.

10.1101/2024.03.22.586261 — microbiology — Posted on 2024-03-24

1363 Surface Hydrophilicity Promotes Bacterial Twitching Motility

O'Hara, M. T.; Dye, K. J.; Shimozono, T.; Harris, D.; Yang, Z.

10.1101/2024.03.23.586342 — microbiology — Posted on 2024-03-24

1364 Bacterial defenses and their trade-off with growth are not ubiquitous but depend on ecological contexts

Liu, Z.-L.; Liu, J.; Niu, D.-K.

10.1101/2024.03.24.586452 — microbiology — Posted on 2024-03-24

1365 Saccharomyces cerevisiae Dmo2p is involved in the mitochondrial copper metabolism and is required for the stability of newly translated Cox2p.

Soares, M. A.; Franco, L. V.; Chagas, J. A.; Gomes, F.; de Barros, M. H.

10.1101/2023.06.12.544600 — molecular biology — Posted on 2024-03-24

1366 Endogenous CD28 drives CAR T cell responses in multiple myeloma

Lieberman, M. M.; Tong, J. H.; Odukwe, N. U.; Chavel, C. A.; Purdon, T. J.; Burchett, R.; Gillard, B. M.; Brackett, C. M.; McGray, A. R.; Bramson, J. L.; Brentjens, R. J.; Lee, K. P.; Olejniczak, S. H.

10.1101/2024.03.21.586084 — cancer biology — Posted on 2024-03-24

1367 Functional Protein Dynamics in a Crystal

Klyshko, E.; Kim, J. S.-H.; McGough, L.; Valeeva, V.; Lee, E.; Ranganathan, R.; Rauscher, S.

10.1101/2023.07.06.548023 — biophysics — Posted on 2024-03-24

1368 Bilingual Language Model for Protein Sequence and Structure

Heinzinger, M.; Weissenow, K.; Gomez Sanchez, J.; Henkel, A.; Mirdita, M.; Steinegger, M.; Rost, B.

10.1101/2023.07.23.550085 — bioinformatics — Posted on 2024-03-24

1369 Towards a Biohybrid Lung? Impacted Endothelial Layer Integrity in Inflammatory Conditions

Cheremkhina, M.; Babendreyer, A.; Neullens, C. T.; Krapp, S.; Pabst, A.; Ohl, K.; Tenbrock, K.; Ruetten, S.; Ludwig, A.; Cornelissen, C. G.; Thiebes, A. L.; Jockenhoevel, S.

10.1101/2023.10.31.564901 — bioengineering — Posted on 2024-03-24

1370 Integrative Omics reveals changes in the cellular landscape of yeast without peroxisomes

Kosir, T.; Das, H.; Pedersen, M. P.; Anteghini, M.; Oeljeklaus, S.; Martins dos Santos, V.; van der Klei, I. J.; Warscheid, B.

10.1101/2024.03.20.585854 — cell biology — Posted on 2024-03-24

1371 Chaperone-Mediated Autophagy in Fish: A Key Function Amid a Changing Environment

Schnebert, S.; Velez, E. J.; Goguet, M.; Dias, K.; Veron, V.; Garcia-Perez, I.; Radler, L. M.; Cardona, E.; Fontagne-Dicharry, S.; Van-Delft, P.; Dittrich-Domergue, F.; Bernard, A.; Beaumatin, F.; Herpin, A.; Cleveland, B.; Seiliez, I.

10.1101/2024.03.20.585855 — cell biology — Posted on 2024-03-24

1372 The common TMEM173 HAQ, AQ alleles rescue CD4 T cellpenia, restore T-regs, and prevent SAVI (N153S) inflammatory disease in mice.

Aybar-Torres, A. a.; saldarriaga, L. A.; Pham, A. T.; Emtiazjoo, A. M.; Sharma, A. K.; Bryant, A. J.; jin, l.

10.1101/2023.10.05.561109 — immunology — Posted on 2024-03-24

1373 Retrieval of an ethanol-conditioned taste aversion promotes GABAergic plasticity in the insular cortex

Taxier, L.; Flanigan, M.; Haun, H.; Kash, T.

10.1101/2024.03.20.585950 — neuroscience — Posted on 2024-03-24

1374 Combining positive and negative regulation for modular and robust biomolecular control architectures

Sechkar, K.; Steel, H.

10.1101/2024.03.22.586143 — synthetic biology — Posted on 2024-03-24

1375 Adaptive Mating Among Natural Strains of S. cerevisiae

Strauss, S. K.; Liti, G.; Dahan, O.; Pilpel, Y. T.

10.1101/2024.02.18.580925 — evolutionary biology — Posted on 2024-03-24

1376 Microbial communities thriving in agave fermentations are locally influenced across diverse biogeographic regions

Jara-Servin, A.; Alcaraz, L. D.; Juarez-Serrano, S. I.; Espinosa-Jaime, A.; Barajas, I.; Morales, L.; DeLuna, A.; Hernandez-Lopez, A.; Mancera, E.

10.1101/2024.03.22.586289 — microbiology — Posted on 2024-03-24

1377 CD4+ T cells facilitate replication of primary HIV-1 strains in macrophages and formation of macrophage internal virus-containing compartments.

Victoria, S.; Leyens, J.; Meckes, L. M.; Turk, G.; Schindler, M.

10.1101/2024.03.22.586250 — microbiology — Posted on 2024-03-24

1378 First evaluation and detection of ivermectin resistance in gastrointestinal nematodes of sheep and goats in South Darfur, Sudan

Mohammedsalih, K. M.; Ibrahim, A. I. Y.; Juma, F.-R.; Abdalmalaik, A. A. H.; Bashar, A.; Coles, G.; von Samson-Himmelstjerna, G.; Krücken, J.

10.1101/2024.03.20.585868 — zoology — Posted on 2024-03-24

1379 NRC immune receptor networks show diversified hierarchical genetic architecture across plant lineages

Goh, F.-J.; Huang, C.-Y.; Derevnina, L.; Wu, C.-H.

10.1101/2023.10.25.563953 — plant biology — Posted on 2024-03-24

1380 Immune gene expression changes more during a malaria transmission season than between consecutive seasons.

Tebben, K.; Yirampo, S.; Coulibaly, D.; Kone, A. K.; Laurens, M. B.; Stucke, E. M.; Dembele, A.; Tolo, Y.; Traore, K.; Niangaly, A.; Berry, A. A.; Kouriba, B.; Plowe, C. V.; Doumbo, O. K.; Lyke, K. E.; Takala-Harrison, S.; Thera, M. A.; Travassos, M. A.; Serre, D.

10.1101/2024.03.20.585963 — bioinformatics — Posted on 2024-03-24

1381 Latest RNA and DNA nanopore sequencing allows for rapid avian influenza profiling

Perlas, A.; Reska, T.; CROVILLE, G.; Tarres-Freixas, F.; Guerin, J.-L.; Majo, N.; Urban, L.

10.1101/2024.02.28.582540 — genomics — Posted on 2024-03-24

1382 Identification of the Mode of Evolution in Incomplete Carbonate Successions

Hohmann, N.; Koelewijn, J. R.; Burgess, P.; Jarochowska, E.

10.1101/2023.12.18.572098 — evolutionary biology — Posted on 2024-03-24

1383 Alstrom syndrome proteins regulate centriolar cartwheel assembly by enabling Plk4-Ana2 amplification loop in Drosophila

Brunet, M.; Thomas, J.; Lapart, J.-A.; Krüttli, L.; Laporte, M.; Riparbelli, M. G.; Callaini, G.; Durand, B.; Morel, V.

10.1101/2023.09.13.557518 — cell biology — Posted on 2024-03-24

1384 The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress

O'Leary, D. R.; Hansen, A. R.; Fingerman, D. F.; Tran, T. A.; Harris, B. R.; Hayer, K. E.; Fan, J.; Chen, E.; Tennekoon, M.; DeWeerd, R. A.; Meroni, A.; Szeto, J.; Weitzman, M. D.; Bednarski, J. J.; Shalem, O.; Vindigni, A.; Zhao, X.; Green, A. M.

10.1101/2023.11.28.568952 — molecular biology — Posted on 2024-03-24

1385 Hippocampal Dipeptidyl Peptidase 9 Bidirectionally Regulates Memory Via Synaptic Plasticity.

Zhao, Y.-B.; Wang, S.; Wang, L.; Guo, W.; Li, J. N.; Xun, T.; Xu, L.; Zhou, Q.-X.

10.1101/2023.11.02.565088 — neuroscience — Posted on 2024-03-24

1386 The archerfish uses motor adaptation in shooting to correct for changing physical conditions

Volotsky, S.; Donchin, O.; Segev, R.

10.1101/2023.10.03.560658 — animal behavior and cognition — Posted on 2024-03-24

1387 The seminal vesicle is a juvenile hormone-responsive tissue in adult male Drosophila melanogaster

Kurogi, Y.; Mizuno, Y.; Okamoto, N.; Barton, L.; Niwa, R.

10.1101/2024.03.20.585833 — physiology — Posted on 2024-03-23

1388 In tissue spatial single-cell metabolomics by coupling mass spectrometry imaging and immunofluorescences

Blanc, L.; Grelard, F.; Tuck, M.; Dartois, V.; Peixoto, A.; Desbenoit, N.

10.1101/2024.03.22.586317 — biochemistry — Posted on 2024-03-23

1389 Specialization in Molecular Functions and Secondary Metabolite Production Potential in Cyanobacterial Symbionts

Cameron, E. S.; Sanchez, S.; Goldman, N.; Blaxter, M.; Finn, R. D.

10.1101/2024.03.22.586251 — genomics — Posted on 2024-03-23

1390 Alzheimer's disease induced neurons bearing PSEN1 mutations exhibit reduced excitability

Maksour, S.; Finol-Urdaneta, R. K.; Hulme, A. J.; Cabral-da-Silva, M. C.; Targa Dias Anastacio, H.; Balez, R.; Berg, T.; Turner, C.; Sanz Munoz, S.; Engel, M.; Kalajdzic, P.; Lisowski, L.; Sidhu, K.; Sachdev, P. S.; Dottori, M.; Ooi, L.

10.1101/2024.03.22.586207 — cell biology — Posted on 2024-03-23

1391 LncRNA-Snhg3 Aggravates Hepatic Steatosis by Regulating PPARγ via SND1/H3K27me3

Xie, X.; Gao, M.; Zhao, W.; Li, C.; Zhang, W.; Yang, J.; Zhang, Y.; Chen, E.; Guo, Y.; Guo, Z.; Zhang, M.; Ngowi, E. E.; Wang, H.; Wang, X.; Zhu, Y.; Wang, Y.; Li, X.; Yao, H.; Yan, L.; Fang, F.; Li, M.; Qiao, A.; Liu, X.

10.1101/2024.03.22.586335 — molecular biology — Posted on 2024-03-23

1392 A computational model for bacteriophage {varphi}X174 gene expression

Hill, A. M.; Ingle, T. A.; Wilke, C. O.

10.1101/2024.03.22.586356 — microbiology — Posted on 2024-03-23

1393 Genetic elements and defense systems drive diversification and evolution in Asgard archaea

Valentin Alvarado, L. E.; Shi, L.-D.; Appler, K. E.; Crits-Christoph, A.; Cui, M. L.; De Anda, V.; Leao, P.; Adler, B. A.; Roberts, R. J.; Sachdeva, R.; Baker, B. J.; Savage, D. F.; Banfield, J.

10.1101/2024.03.22.586370 — microbiology — Posted on 2024-03-23

1394 Hepatitis E virus infection upregulates ING5 expression in vitro and vivo

Zhao, W.; Xia, Y.; Li, T.; Liu, H.; Zhong, G.; Chen, D.; Yu, W.; Li, Y.; Huang, F.

10.1101/2024.03.22.586368 — microbiology — Posted on 2024-03-23

1395 The L-lactate dehydrogenases of Pseudomonas aeruginosa are conditionally regulated but both contribute to survival during macrophage infection

Florek, L. C.; Lin, X.; Lin, Y.-C.; Chakraborty, A.; Lin, M.-H.; Price-Whelan, A.; Tong, L.; Rahme, L.; Dietrich, L. E. P.

10.1101/2024.03.21.586142 — microbiology — Posted on 2024-03-23

1396 Novel oil-associated bacteria in Arctic seawater exposed to different nutrient biostimulation regimes

Davila Aleman, F. D.; Bautista, M. A.; McCalder, J.; Jobin, K.; Murphy, S. M. C.; Else, B.; Hubert, C. R.

10.1101/2024.03.22.586348 — microbiology — Posted on 2024-03-23

1397 Laboratory evolution in Novosphingobium aromaticivorans enables rapid catabolism of a model lignin-derived aromatic dimer

Allemann, M. N.; Kato, R.; Alexander, W. G.; Giannone, R. J.; Kamimura, N.; Masai, E.; Michener, J. K.

10.1101/2024.03.22.586352 — microbiology — Posted on 2024-03-23

1398 Deciphering the RNA-binding protein network during endosomal mRNA transport

Devan, S. K.; Shanmugasundaram, S.; Muentjes, K.; Smits, S. H.; Altegoer, F.; Feldbrugge, M.

10.1101/2024.03.22.586338 — microbiology — Posted on 2024-03-23

1399 Neural networks built from enzymatic reactions can operate as linear and nonlinear classifiers

Cuba Samaniego, C.; Wallace, E.; Blanchini, F.; Franco, E.; Giordano, G.

10.1101/2024.03.23.586372 — synthetic biology — Posted on 2024-03-23

1400 SUC2 sucrose transporter is required for leaf apoplasmic sucrose levels. Consequences for phloem loading strategies

Vilaine, F.; Bill, L.; Le Hir, R.; Bellini, C.; Dinant, S.

10.1101/2024.03.20.585851 — plant biology — Posted on 2024-03-23

1401 Cathodoluminescent and Characteristic X-ray-emissive Rare-Earth-doped Core/Shell Immunolabels for Spectromicroscopic Analysis of Cell Surface Receptors

Habermann, S.; Gerken, L. R. H.; Kociak, M.; Monachon, C.; Kissling, V. M.; Gogos, A.; Herrmann, I. K.

10.1101/2024.03.20.585848 — bioengineering — Posted on 2024-03-23

1402 Snapshots of Pseudomonas aeruginosa SOS response activation complex reveal structural prerequisites for LexA engagement and cleavage

Vascon, F.; De Felice, S.; Gasparotto, M.; Huber, S.; Catalano, C.; Chinellato, M.; Grinzato, A.; Filippini, F.; Maso, L.; Jakobi, A. J.; Cendron, L.

10.1101/2024.03.22.585941 — biochemistry — Posted on 2024-03-23

1403 Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion

Keutler, K.; Hauke, S.; Laguerre, A.; Andreu-Carbo, M.; Rada, J.; Grandy, D.; Yushchenko, D. A.; Schultz, C.

10.1101/2024.03.21.585773 — biochemistry — Posted on 2024-03-23

1404 The priming phosphorylation of KaiC is activated by the release of its autokinase autoinhibition

Furuike, Y.; Onoue, Y.; Saito, S.; Mori, T.; Akiyama, S.

10.1101/2024.03.21.584037 — biochemistry — Posted on 2024-03-23

1405 A candidate reference method for the quantification of α-synuclein in cerebrospinal fluid using an SI traceable primary calibrator and multiple reaction monitoring

Zhang, L.; Iles-Toth, E.; Cryar, A.; Drinkwater, G.; Di Vagno, L.; Pons, M.-L.; Mateyka, J.; McCullough, B.; Achtar, E.; Clarkson, C.; Goeschel, L.; Koertvelyessy, P.; Mussell, C.; Hopley, C.; Floeel, A.; Hirtz, C.; Lehmann, S.; Quaglia, M.

10.1101/2024.03.20.585804 — biochemistry — Posted on 2024-03-23

1406 Measuring X inactivation skew for retinal diseases with adaptive nanopore sequencing

Gocuk, S. A.; Lancaster, J.; Su, S.; Jolly, J. K.; Edwards, T. L.; Hickey, D. G.; Ritchie, M. E.; Blewitt, M. E.; Ayton, L. N.; Gouil, Q.

10.1101/2024.03.20.585856 — genomics — Posted on 2024-03-23

1407 Trait evolution linked to climatic shifts contributes to adaptive divergence in an alpine carnation (Dianthus sylvestris)

Paalsson, A.; Fior, S.; Widmer, A.

10.1101/2024.03.22.586106 — evolutionary biology — Posted on 2024-03-23

1408 Simulating animal movement trajectories from temporally dynamic step selection functions

Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.

10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-23

1409 Bacteria adapt nutrient deprivation by reducing vacant 70S ribosomes via the silencing factor RsfS

Qin, B.; Zhang, H.; Nikolay, R.; Jiang, L.; Brotman, Y.; Zhang, G.

10.1101/2024.03.23.586405 — microbiology — Posted on 2024-03-23

1410 Host cell-specific metabolism of linoleic acid controls Toxoplasma gondii growth in cell culture

Hryckowian, N. D.; Zinda, C.; Park, S. C.; Kelty, M. T.; Knoll, L. J.

10.1101/2024.03.22.586332 — microbiology — Posted on 2024-03-23

1411 Transcription factor EB (TFEB) interaction with RagC is disrupted during Enterovirus D68 Infection

Jassey, A.; Pollack, N.; Wagner, M. A.; Wu, J.; Benton, A.; Jackson, W. T.

10.1101/2024.03.23.586376 — microbiology — Posted on 2024-03-23

1412 Egoviruses: distant relatives of poxviruses abundant in the gut microbiome of humans and animals worldwide

Gaia, M.; Ruscheweyh, H.-J.; Eren, A. M.; Koonin, E. V.; Sunagawa, S.; Krupovic, M.; Delmont, T. O.

10.1101/2024.03.23.586382 — microbiology — Posted on 2024-03-23

1413 Constant companions: Wild zebra finch pairs display extreme spatial cohesion

Tyson, C.; Loning, H.; Griffith, S.; Naguib, M.

10.1101/2024.03.21.586046 — animal behavior and cognition — Posted on 2024-03-23

1414 Ecogeographic signals of local adaptation in a wild relative help to identify variants associated with improved wheat performance under drought stress

Nyine, M.; Davidson, D.; Adhikari, E.; Clinesmith, M.; Wang, H.; Akhunova, A.; Fritz, A.; Akhunov, E.

10.1101/2024.03.20.585976 — genetics — Posted on 2024-03-23

1415 Reproductive modes of polyploid Ludwigia grandiflora subsp. hexapetala in western Europe: the effects of a late-acting self-incompatibility system and its absence on genetic diversity within populations

stoeckel, S.; Becheler, R.; Portillo-Lemus, L.; Harang, M.; Besnard, A.-L.; Lassalle, G.; Causse-Vedrines, R.; Michon-Coudouel, S.; Park, D. J.; Pope, B.; Petit, E. J.; BARLOY, D. H.

10.1101/2024.03.21.586104 — evolutionary biology — Posted on 2024-03-23

1416 Seasonal genotypic and phenotypic differentiation of a cosmopolitan freshwater diatom

Cristini, D.; Kelly, J. B.; Mahler, P.; Becks, L.

10.1101/2024.03.20.585933 — ecology — Posted on 2024-03-23

1417 Phospholipase C β4 promotes RANKL-dependent osteoclastogenesis by interacting with MKK3 and p38 MAPK

Lee, D.-K.; Jin, X.; Choi, P.-R.; Cui, Y.; Che, X.; Lee, S.; Hur, K.; Kim, H.-J.; Choi, J.-Y.

10.1101/2024.03.19.585823 — cell biology — Posted on 2024-03-23

1418 Rodent Gut Bacteria Coexisting with an Insect Gut Virus in Parasitic Cysts: Metagenomic Evidence of Microbial Translocation and Co-adaptation in Spatially-Confined Niches

Ammar, A.; Singh, V.; Ilic, S.; Samiksha, F.; Marsh, A.; Rodriguez-Palacios, A.

10.1101/2024.03.22.585885 — microbiology — Posted on 2024-03-23

1419 Antigenic drift expands viral escape pathways from imprinted host humoral immunity

Maurer, D. P.; Vu, M.; Schmidt, A. G.

10.1101/2024.03.20.585891 — immunology — Posted on 2024-03-23

1420 Aberrant neuronal hyperactivation causes an age- and diet-dependent decline in associative learning behavior

Aleogho, B. M.; Mohri, M.; Jang, M. S.; Tsukada, S.; Al-Hebri, Y.; Tsukada, Y.; Mori, I.; Noma, K.

10.1101/2024.03.21.586045 — neuroscience — Posted on 2024-03-23

1421 Multi-omics of a rice population identifies genes and genomic regions in rice that bestow low glycemic index and high protein content

Badoni, S.; Pasion, E.; Kor, S.; Kim, S.-R.; Misra, G.; Tiozon, R. N.; Buenafe, R. J.; Ramos-Castrosanto, A.-R.; Pratap, V.; Slamet-Loedin, I.; von Steimker, J.; Alseekh, S.; Fernie, A. R.; Kohli, A.; Khush, G.; Sreenivasulu, N.

10.1101/2024.03.21.586029 — systems biology — Posted on 2024-03-23

1422 The cage effect of electron beam irradiation damage in cryo-electron microscopy

Li, Y.; Kang, D.-d.; Dai, J.-y.; Wang, L.-w.

10.1101/2024.03.20.585930 — biophysics — Posted on 2024-03-23

1423 Molecular events accompanying aggregation-induced energy quenching in Fucoxanthin-Chlorophyll Proteins

Alexandre, M. M.; Kruger, T. P.; Pascal, A. A.; Veremeienko, V.; Llansola-Portoles, M.; Gundermann, K.; van Grondelle, R.; Buechel, C.; Robert, B.

10.1101/2024.03.20.585890 — biophysics — Posted on 2024-03-23

1424 EXPLANA: A user-friendly workflow for EXPLoratory ANAlysis and feature selection in cross-sectional and longitudinal microbiome studies

Fouquier, J.; Stanislawski, M.; O'Connor, J.; Scadden, A.; Lozupone, C.

10.1101/2024.03.20.585968 — bioinformatics — Posted on 2024-03-23

1425 DrugDomain: the evolutionary context of drugs and small molecules bound to domains

Medvedev, K. E.; Schaeffer, R. D.; Grishin, N. V.

10.1101/2024.03.20.585940 — bioinformatics — Posted on 2024-03-23

1426 scDTL: single-cell RNA-seq imputation based on deep transfer learning using bulk cell information

Tian, J.; Zhao, L.; Xie, Y.; Jiang, L.; Huang, J.; Xie, H.; Zhang, D.

10.1101/2024.03.20.585898 — bioinformatics — Posted on 2024-03-23

1427 Searching Post-translational Modifications in Cross-linking Mass Spectrometry Data

Zhou, C.; Lai, S.; DAI, S.; Zhao, P.; Li, N.; Yu, W.

10.1101/2024.03.20.585841 — bioinformatics — Posted on 2024-03-23

1428 Low-intensity vibration does not induce changes in microtubule dynamics in vitro

Crandall, C.; Nikitina, N. N.; Zavala, A. G.; Howard, S. M.; Uzer, G.

10.1101/2024.03.20.585904 — bioengineering — Posted on 2024-03-23

1429 Development of a high-throughput, quantitative platform using human cerebral organoids to study virus-induced neuroinflammation in Alzheimer's disease

Olson, M. N.; Dawes, P.; Murray, L. F.; Barton, N. J.; Sundstrom, J.; Orszulak, A. R.; Chigas, S. M.; Tran, K.; Aylward, A. J.; Caliandro, M. F.; Riechers, S.-P. H.; Afshari, K.; Wang, Q.; Garber, M.; Humphries, F.; Orzalli, M. H.; Golenbock, D. T.; Heneka, M. T.; Oh, H. S.; Church, G. M.; Young-Pearse, T. L.; Knipe, D. M.; Readhead, B.; Chan, Y.; Lim, E. T.

10.1101/2024.03.21.585957 — genomics — Posted on 2024-03-23

1430 Single cell RNA sequencing of nc886, a non-coding RNA transcribed by RNA polymerase III, with a primer spike-in strategy

Shin, G.-J.; Choi, B.-H.; Eum, H. H.; Jo, A.; Kim, N.; Kang, H.; Hong, D.; Jan, J. J.; Lee, H.-H.; Lee, Y.-S.; Lee, Y. S.; Lee, H.-O.

10.1101/2024.03.20.585884 — genomics — Posted on 2024-03-23

1431 Rapid evolution of recombination landscapes during the divergence of cichlid ecotypes in Lake Masoko

Talbi, M.; Turner, G. F.; Malinsky, M.

10.1101/2024.03.20.585960 — evolutionary biology — Posted on 2024-03-23

1432 Floral phenotypic divergence and genomic insights in an Ophrys orchid: Unraveling early speciation processes

Gibert, A.; Schatz, B.; Buscail, R.; Nguyen, D.; Baguette, M.; Barthes, N.; Bertrand, J. A. M.

10.1101/2024.03.21.586062 — evolutionary biology — Posted on 2024-03-23

1433 EcologicalNetworksDynamics.jl: A Julia package to simulate the temporal dynamics of complex ecological networks

Lajaaiti, I.; Bonnici, I.; Kefi, S.; Mayall, H.; Danet, A.; Beckerman, A. P.; Malpas, T.; Delmas, E.

10.1101/2024.03.20.585899 — ecology — Posted on 2024-03-23

1434 Effect of copper mill waste material on benthic invertebrates and zooplankton diversity and abundance in Lake Superior beaches

Larson, J. H.; Lowe, M. R.; Bailey, S. W.; Bell, A. H.; Cleveland, D. M.

10.1101/2024.03.20.585947 — ecology — Posted on 2024-03-23

1435 Hypothalamic Sex-Specific Metabolic Shift by Canagliflozin during Aging

Jayarathne, H. S. M.; Sullivan, R.; Stilgenbauer, L.; Debarba, L. K.; Kuchumov, A.; Koshko, L.; Scofield, S.; Liu, W.; Ginsburg, B. C.; Miller, R. A.; Sadagurski, M.

10.1101/2024.03.21.586115 — neuroscience — Posted on 2024-03-23

1436 Do you see what I see? Diffusion imaging protocol heterogeneity biases ischemic core volume, location, and clinical associations in acute stroke

Rafael-Patino, J.; Fischi-Gomez, E.; Madrona, A.; Ravano, V.; Marechal, B.; Kober, T.; Pistocchi, S.; Salerno, A.; Saliou, G.; Michel, P.; Wiest, R.; McKinley, R. I.; Richiardi, J.

10.1101/2024.03.19.585494 — neuroscience — Posted on 2024-03-23

1437 How does perception of zoo animal welfare influence public attitudes, experiences, and behavioural intentions? A mixed-methods systematic review

Phillips, N.; Marechal, L.; Ventura, B.; Cooper, J.

10.1101/2024.03.20.585889 — zoology — Posted on 2024-03-23

1438 Attention-based approach to predict drug-target interactions across seven target superfamilies

Schulman, A.; Rousu, J.; Aittokallio, T.; Tanoli, Z.

10.1101/2024.03.20.585893 — systems biology — Posted on 2024-03-23

1439 Uncovering organizing principles of protein-protein interaction networks

Ojha, A. K.; Dhar, P. K.

10.1101/2024.03.20.585897 — systems biology — Posted on 2024-03-23

1440 A Comparative Study on the Superiority of AOS DP3-7 Over 5-ALA in Facilitating Pigment Change in Peppers

Chen, X.; Chen, H.; Shang, Z.

10.1101/2024.03.19.585827 — plant biology — Posted on 2024-03-23

1441 A frosty genetic screen unmasks a major regulatory role for SHORT VEGETATIVE PHASE of flowering in response to a cold snap

Edwards, A.; Thordal-Christensen, H.; Wenkel, S.

10.1101/2024.03.20.585907 — plant biology — Posted on 2024-03-23

1442 Pharmacological inhibition of tyrosine protein-kinase 2 reduces islet inflammation and delays type 1 diabetes onset in mice

Syed, F.; Ballew, O.; Lee, C.-C.; Rana, J.; Krishnan, P.; Castela, A.; Weaver, S. A.; Chalasani, N. S.; Thomaidou, S. F.; Demine, S.; Chang, G.; Coomans de Brachene, A.; Alvelos, M. I.; Marselli, L.; Orr, K.; Felton, J. L.; Liu, J.; Marchetti, P.; Zaldumbide, A.; Scheuner, D.; Eizirik, D. L.; Evans-Molina, C.

10.1101/2024.03.20.585925 — physiology — Posted on 2024-03-23

1443 Characterization of novel role for Rab27B in autophagy regulation in colorectal cancer

Afroz, S.; Preet, R.; Vishwakarma, V.; Evans, A. E.; Dixon, D. A.

10.1101/2024.03.22.586334 — cancer biology — Posted on 2024-03-23

1444 Assembly Arena: Benchmarking RNA isoform reconstruction algorithms for nanopore sequencing

Sagniez, M.; Budhraja, A.; Pare, B.; Simpson, S. M.; Vinet-Ouellette, C.; Rozendaal, M.; Smith, M. A.

10.1101/2024.03.21.586080 — bioinformatics — Posted on 2024-03-23

1445 Screening of glucose binding proteins for the development of biosensors

Makare, A.; Chaudhary, A.; De, D.; Deshpande, P.; Panwar, A.

10.1101/2024.03.20.585966 — bioinformatics — Posted on 2024-03-23

1446 ProtAlign-ARG: Antibiotic Resistance Gene Characterization Integrating Protein Language Models and Alignment-Based Scoring

Ahmed, S.; Emon, M. I.; Moumi, N. A.; Huang, L.; Zhou, D.; Vikesland, P.; Pruden, A.; ZHANG, L.

10.1101/2024.03.20.585944 — bioinformatics — Posted on 2024-03-23

1447 Physics-informed machine learning for automatic model reduction in chemical reaction networks

Pateras, J.; Ghosh, P.; Zhang, C.; Majumdar, S.; Pal, A.

10.1101/2024.03.20.585845 — biochemistry — Posted on 2024-03-23

1448 FEVER: An interactive web-based resource for evolutionary transcriptomics across fishes

Montfort, J.; Hervas-Sotomayor, F.; Le Cam, A.; Murat, F.

10.1101/2024.03.22.586044 — evolutionary biology — Posted on 2024-03-23

1449 Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy

Joers, V.; Murray, B. C.; McLaughlin, C.; Oliver, D.; Staley, H.; Coronado, J. E.; Achat-Mendes, C.; Golshani, S.; Kelly, S. D.; Goodson, M.; Lee, D.; Manfredsson, F. P.; Moore, B. M.; Tansey, M. G.

10.1101/2023.08.25.554814 — immunology — Posted on 2024-03-23

1450 Novel Cyclic Homogeneous Oscillation Detection Method for High Accuracy and Specific Characterization of Neural Dynamics

Cho, H.; Adamek, M.; Willie, J. T.; Brunner, P.

10.1101/2023.10.04.560843 — neuroscience — Posted on 2024-03-23

1451 Structure of Aquifex aeolicus Lumazine Synthase by Cryo-Electron Microscopy to 1.42 Angstrom Resolution

Savva, C. G.; Sobhy, M. A.; De Biasio, A.; Hamdan, S. M.

10.1101/2024.03.21.586070 — biophysics — Posted on 2024-03-23

1452 All eukaryotic SMC proteins induce a twist of -0.6 at each DNA-loop-extrusion step

Janissen, R.; Barth, R.; Davidson, I. F.; Taschner, M.; Gruber, S.; Peters, J.-M.; Dekker, C.

10.1101/2024.03.22.586328 — biophysics — Posted on 2024-03-23

1453 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.

Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.

10.1101/2024.03.22.584691 — genetics — Posted on 2024-03-23

1454 The evolution of morphological castes under decoupled control

Flintham, L.; Field, J.

10.1101/2023.02.21.529356 — evolutionary biology — Posted on 2024-03-23

1455 Asynchronous abundance fluctuations can drive giant genotype frequency fluctuations

Ascensao, J. A.; Lok, K.; Hallatschek, O.

10.1101/2024.02.23.581776 — evolutionary biology — Posted on 2024-03-23

1456 Potential impact of climate change on Nearctic leafhopper distribution and richness in North America

Santos, A. A.; Jacques, J.; Perez-Lopez, E.

10.1101/2023.12.13.571535 — ecology — Posted on 2024-03-23

1457 Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues

Pearson, G. L.; Walker, E. M.; Lawlor, N.; Lietzke, A.; Sidarala, V.; Zhu, J.; Stromer, T.; Reck, E. C.; Stendahl, A. M.; Li, J.; Levi-D'Ancona, E.; Pasmooij, M. B.; Hubers, D. L.; Renberg, A.; Mohamed, K.; Parekh, V. S.; Zhang, I. X.; Thompson, B.; Zhang, D.; Ware, S. A.; Haataja, L.; Parker, S. C. J.; Arvan, P.; Yin, L.; Kaufman, B. A.; Satin, L. S.; Sussel, L.; Stitzel, M. L.; Soleimanpour, S. A.

10.1101/2022.08.02.502357 — cell biology — Posted on 2024-03-23

1458 Prevalence and preferred niche of small eukaryotes with mixotrophic potentials in the global ocean

Dong, K.; Wang, Y.; Zhang, W.; Li, Q.

10.1101/2024.02.17.580790 — microbiology — Posted on 2024-03-23

1459 A Large Field-of-view, Single-cell-resolution Two- and Three-Photon Microscope for Deep and Wide Imaging

Mok, A.; Wang, T.; Zhao, S.; Kolkman, K.; Wu, D.; Ouzounov, D.; Seo, C.; Wu, C.; Fetcho, J.; Xu, C.

10.1101/2023.11.14.566970 — neuroscience — Posted on 2024-03-23

1460 Pulsatile electrical stimulation creates predictable, correctable disruptions in neural firing

Steinhardt, C. R.; Mitchell, D. E.; Cullen, K. E.; Fridman, G. Y.

10.1101/2021.08.18.456731 — neuroscience — Posted on 2024-03-23

1461 Maximum Likelihood Inference of Time-scaled Cell Lineage Trees with Mixed-type Missing Data

Mai, U.; Chu, G.; Raphael, B.

10.1101/2024.03.05.583638 — systems biology — Posted on 2024-03-23

1462 Young Eurasian Scops Owls produce individually distinctive vocalizations

Grieco, F.

10.1101/2023.09.17.558098 — animal behavior and cognition — Posted on 2024-03-23

1463 CFL1-dependent dynamicity of surface ectoderm filopodia-like protrusions increases neurulation zippering speed in mice

Marshall, A.; Krstevski, A.; Crosswell, H.; Shah, R.; Maniou, E.; Greene, N.; Copp, A.; Galea, G. L.

10.1101/2023.11.07.565942 — developmental biology — Posted on 2024-03-23

1464 Genome-wide in vivo CRISPR screens identify GATOR1 as a potent tumor suppressor and its loss sensitizes MYC-driven lymphomas to mTOR inhibition

Potts, M. A.; Mizutani, S.; Deng, Y.; Vaidyanathan, S.; Ting, K.; Giner, G.; Shruti, S.; Liao, Y.; Diepstraten, S.; Kueh, A. J.; Pal, M.; Healey, G.; Tai, L.; Wang, Z.; Koenig, C.; Kaloni, D.; Whelan, L.; Milevskiy, M.; Pomilio, G.; Wei, A.; Visvader, J. E.; Papenfuss, A. T.; Wilcox, S.; Jeyasekharan, A.; Shi, W.; Lelliott, E.; Kelly, G. L.; Brown, K.; Strasser, A.; Herold, M. J.

10.1101/2022.02.16.480657 — cancer biology — Posted on 2024-03-23

1465 An ab initio information-theoretic approach to proteins and protein-ligand interactions

Nath, D.; Grewal, R. K.; Mitra, D.; Roy, S.

10.1101/2024.03.06.583646 — biophysics — Posted on 2024-03-23

1466 Identification of Novel Allosteric Sites of SARS-CoV-2 Papain-Like Protease (PLpro) for the Development of COVID-19 Antivirals

Ferreira, J. C.; Al Adem, K.; Fadl, S.; Villanueva, A. J.; Alzyoud, L.; Ghattas, M. A.; Rabeh, W. M.

10.1101/2023.05.16.540953 — biochemistry — Posted on 2024-03-23

1467 GLMsim: a GLM-based single cell RNA-seq simulator incorporating batch and biological effects

Wang, J.; Chen, L.; Thijssen, R.; Phipson, B.; Speed, T. P.

10.1101/2024.03.20.586030 — bioinformatics — Posted on 2024-03-23

1468 Consensus Clustering for Robust Bioinformatics Analysis

Yousefi, B.; Schwikowski, B.

10.1101/2024.03.21.586064 — bioinformatics — Posted on 2024-03-23

1469 Upstream open reading frames may contain hundreds of novel human exons

Ji, H. J.; Salzberg, S.

10.1101/2024.03.22.586333 — genomics — Posted on 2024-03-23

1470 A zebrafish system for identifying genetic dependencies in melanocytes and melanoma

Perlee, S.; Ma, Y.; Hunter, M. V.; Swanson, J. B.; Ming, Z.; Xia, J.; Lionnet, T.; McGrail, M.; White, R.

10.1101/2024.03.22.586101 — genetics — Posted on 2024-03-23

1471 SQUARNA - an RNA secondary structure prediction method based on a greedy stem formation model

Bohdan, D. R.; Nikolaev, G. I.; Bujnicki, J. M.; Baulin, E. F.

10.1101/2023.08.28.555103 — bioinformatics — Posted on 2024-03-23

1472 A simplified femtosecond laser repetition frequency divider for two-photon imaging

Tang, S.

10.1101/2023.07.02.547378 — neuroscience — Posted on 2024-03-23

1473 Effort Drives Saccade Selection

Koevoet, D.; Van Zantwijk, L.; Naber, M.; Mathot, S.; Van der Stigchel, S.; Strauch, C.

10.1101/2024.02.06.579052 — neuroscience — Posted on 2024-03-23

1474 Individuality across environmental context in Drosophila melanogaster

Mathejczyk, T.; Knief, C.; Haidar, M. A.; Freitag, F.; McClary, T.; Wernet, M. F.; Linneweber, G. A.

10.1101/2023.11.26.568741 — neuroscience — Posted on 2024-03-23

1475 Structure, substrate selectivity determinants and membrane interactions of a Glutamate-specific TAXI TRAP binding protein from Vibrio cholerae.

Davies, J. F.; Daab, A.; Massouh, N.; Kirkland, C.; Strongitharm, B.; Leech, A.; Farre, M.; Thomas, G. H.; Mulligan, C.

10.1101/2024.03.22.586268 — biochemistry — Posted on 2024-03-23

1476 Evidence that metastases arise de novo as new cancers from cells of target organs

Raghuram, G. V.; Pal, K.; Shende, S.; Khare, N. K.; Jadhav, V.; Shinde, S.; Prasad, R.; Wani, H.; Mittra, I.

10.1101/2023.08.09.552586 — cancer biology — Posted on 2024-03-23

1477 Do sister species respond similarly to dry conditions? An ecophysiological approach in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-03-22

1478 Boosting biodiversity monitoring using smartphone-driven, rapidly accumulating community-sourced data

Atsumi, K.; Nishida, Y.; Ushio, M.; Nishi, H.; Genroku, T.; Fujiki, S.

10.1101/2023.09.13.557657 — ecology — Posted on 2024-03-22

1479 Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance

Mitra, N.; Mishra, D.; Puthethu, I. A.; SRINIVASAN, R.

10.1101/2024.03.17.585406 — microbiology — Posted on 2024-03-22

1480 Optical quantification of molecular interaction strength in protein condensates

Beck, T.; van der Linden, L.-M.; Borcherds, W. M.; Kim, K.; Schluessler, R.; Mueller, P.; Franzmann, T.; Moeckel, C.; Goswami, R.; Leaver, M.; Mittag, T.; Alberti, S.; Guck, J.

10.1101/2024.03.19.585750 — biophysics — Posted on 2024-03-22

1481 In search of visual opsin of Lissachatina fulica: in silico prediction

Fedotov, D. A.; Dominova, I. N.; Zhukov, V. V.; Shirina, S.; Zikin, V.

10.1101/2024.03.19.585790 — biophysics — Posted on 2024-03-22

1482 Dominance Analysis: A formalism to uncover dominant energetic contributions to biomolecular condensate formation in multicomponent systems

Qian, D.; Ausserwoger, H.; Sneideris, T.; Farag, M.; Pappu, R. V.; Knowles, T.

10.1101/2023.06.12.544666 — biophysics — Posted on 2024-03-22

1483 Linking modulation of bio-molecular phase behaviour with collective interactions

Qian, D.; Ausserwoger, H.; Arter, W. E.; Scrutton, R.; Welsh, T. J.; Kartanas, T.; Ermann, N.; Qamar, S.; Fischer, C.; Sneideris, T.; St George-Hyslop, P.; Pappu, R. V.; Knowles, T.

10.1101/2023.11.02.565376 — biophysics — Posted on 2024-03-22

1484 Modulation of Biophysical Properties of Nucleocapsid Protein in the Mutant Spectrum of SARS-CoV-2

Nguyen, A.; Zhao, H.; Myagmarsuren, D.; Srinivasan, S.; Wu, D.; Chen, J.; Piszczek, G.; Schuck, P.

10.1101/2023.11.21.568093 — biophysics — Posted on 2024-03-22

1485 CHAI: Consensus Clustering Through Similarity Matrix Integration for Cell-Type Identification

Lodi, M.; Lodi, M.; Osei, K.; Ranganathan, V.; Hwang, P.; Ghosh, P.

10.1101/2024.03.19.585758 — bioinformatics — Posted on 2024-03-22

1486 Transformer Model Generated Bacteriophage Genomes are Compositionally Distinct from Natural Sequences

Ratcliff, J. D.

10.1101/2024.03.19.585716 — bioinformatics — Posted on 2024-03-22

1487 NEST: Spatially-mapped cell-cell communication patterns using a deep learning-based attention mechanism

Zohora, F. T.; Flores-Figueroa, E.; Li, J.; Paliwal, D.; Notta, F.; Schwartz, G. W.

10.1101/2024.03.19.585796 — bioinformatics — Posted on 2024-03-22

1488 Multiscale computational model predicts how environmental changes and drug treatments affect microvascular remodeling in fibrotic disease

Leonard-Duke, J.; Agro, S. M. J.; Csordas, D. J.; Bruce, A. C.; Eggertsen, T. G.; Tavakol, T. N.; Barker, T. H.; Bonham, C. A.; Saucerman, J. J.; Taite, L. J.; Peirce, S. M.

10.1101/2024.03.15.585249 — bioengineering — Posted on 2024-03-22

1489 Structure, substrate selectivity determinants and membrane interactions of a Glutamate-specific TAXI TRAP binding protein rom Vibrio cholerae.

Davies, J. F.; Daab, A.; Massouh, N.; Kirkland, C.; Strongitharm, B.; Leech, A.; Farre, M.; Thomas, G. H.; Mulligan, C.

10.1101/2024.03.22.586268 — biochemistry — Posted on 2024-03-22

1490 Cohesin supercoils DNA during loop extrusion

Davidson, I. F.; Barth, R.; Horn, S.; Janissen, R.; Nagasaka, K.; Wutz, G.; Stocsits, R. R.; Bauer, B.; Dekker, C.; Peters, J.-M.

10.1101/2024.03.22.586228 — biochemistry — Posted on 2024-03-22

1491 Delving into human α1,4-galactosyltransferase acceptor specificity: the role of enzyme dimerization

Mikolajczyk, K.; Wroblewski, K.; Kmiecik, S.

10.1101/2024.03.21.586141 — biochemistry — Posted on 2024-03-22

1492 Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach

Merten, E. M.; Sears, J. D.; Leisner, T. M.; Hardy, P. B.; Ghoshal, A.; Hossain, M. A.; Asressu, K. H.; Brown, P. J.; Stashko, M. A.; Herring, L. E.; Mordant, A. L.; Webb, T. S.; Mills, C. A.; Barker, N. K.; Arnold, J. J.; Cameron, C. E.; Streblow, D. N.; Moorman, N. J.; Heise, M.; Willson, T. M.; Popov, K. I.; Pearce, K. H.

10.1101/2024.03.22.586341 — biochemistry — Posted on 2024-03-22

1493 Discovery, Characterization and Synthetic Potential of Two Novel Bacterial Alcohol Oxidases

Cinca-Fernando, P.; Ascaso-Alegre, C.; Sevilla, E.; Martinez-Julvez, M.; Mangas-Sanchez, J.; Ferreira, P.

10.1101/2024.03.22.586125 — biochemistry — Posted on 2024-03-22

1494 The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes

Krokengen, O. C.; Touma, C.; Mularski, A.; Sutinen, A.; Dunkel, R.; Ytterdal, M.; Raasakka, A.; Mertens, H. D. T.; Simonsen, A. C.; Kursula, P.

10.1101/2024.03.22.586069 — biochemistry — Posted on 2024-03-22

1495 VASP phase separation with priming proteins of fast endophilin mediated endocytosis modulates actin polymerization

Narayan, K. B.; James, H. P.; Cope, J.; Mondal, S.; Baeyens, L.; Milano, F.; Zheng, J.; Krause, M.; Baumgart, T.

10.1101/2024.03.21.586200 — biochemistry — Posted on 2024-03-22

1496 Single RNA molecule resolution spatial imaging of immunotherapy response in triple negative breast tumors harboring tertiary lymphoid structures

Mebane, R.; Noel, T.; Ing, N.; Gouin, K.; Shah, A.; Zitser, D.; Matinez, A.; Gupta, G. P.; Ho, A.; McArthur, H.; Shiao, S. L.; Knott, S. R. V.

10.1101/2024.03.19.585798 — genomics — Posted on 2024-03-22

1497 Probing chromatin accessibility with small molecule DNA intercalation and nanopore sequencing

Bai, G.; Dhillon, N.; Felton, C. A.; Meissner, B.; Saint-John, B.; Shelansky, R.; Meyerson, E.; Hrabeta-Robinson, E.; Hodjat, B.; Boeger, H.; Brooks, A. N.

10.1101/2024.03.20.585815 — genomics — Posted on 2024-03-22

1498 Anatomy of a pest control failure: Introgression of cytochrome P450 337B3 alleles from invasive old-world bollworm into native corn earworm.

Nufer, M. I.; Coates, B. S.; Abel, C. A.; O'Neill, P.; McKracken, M.; Jain, D.; Pierce, C. A.; Glover, J.; Towles, T.; Reddy, G. V. P.; Perera, O. P.

10.1101/2024.03.22.584691 — genetics — Posted on 2024-03-22

1499 A humanized knock-in Col6a1 mouse recapitulates a deep-intronic splice-activating variant

Bolduc, V.; Guirguis, F.; Lubben, B.; Trank, L.; Silverstein, S.; Brull, A.; Nalls, M.; Cheng, J.; Garrett, L.; Bonnemann, C. G.

10.1101/2024.03.21.581572 — genetics — Posted on 2024-03-22

1500 The equilibrium theory of biodiversity dynamics: a general framework for scaling species richness and community abundance along environmental gradients

Okie, J. G.; Storch, D.

10.1101/2023.07.17.549376 — ecology — Posted on 2024-03-22

1501 Adipokinetic hormone signaling mediates the enhanced fecundity of Diaphorina citri infected by 'Candidatus Liberibacter asiaticus'

Li, J.; Holford, P.; Beattie, G. A. C.; Wu, S.; He, J.; Tan, S.; Wang, D.; He, Y.; Cen, Y.; Nian, X.

10.1101/2023.10.24.563719 — ecology — Posted on 2024-03-22

1502 MALAT1 mediates miR-206/CDC42/PAK1/Paxillin signaling axis to alleviate erectile dysfunction in rats

Luo, L.; Wang, Z.; Tong, X.; Xiong, T.; Chen, M.; Liu, X.; Peng, C.; Sun, X.

10.1101/2024.03.21.586086 — molecular biology — Posted on 2024-03-22

1503 Cannabinoid Receptor Signaling is Dependent on Sub-Cellular Location

Thomas, A.; Lobingier, B.; Schultz, C.; Laguerre, A.

10.1101/2024.03.21.586146 — molecular biology — Posted on 2024-03-22

1504 DNA damage drives antigen diversification through mosaic VSG formation in Trypanosoma brucei

Smith, J. E.; Wang, K. J.; Hakim, J. M.; Beaver, A. K.; Magesh, A.; Gilligan-Steinberg, S. D.; Zheng, J.; So, J.; Kennedy, E. M.; Zhang, B.; Akin, E. H.; Mwakibete, L.; Mugnier, M. R.

10.1101/2024.03.22.582209 — microbiology — Posted on 2024-03-22

1505 Predicting microbial growth conditions from amino acid composition

Barnum, T. P.; Crits-Christoph, A.; Molla, M.; Carini, P.; Lee, H. H.; Ostrov, N.

10.1101/2024.03.22.586313 — microbiology — Posted on 2024-03-22

1506 Limited potexvirus diversity in seagrasses

Lim, S. J.; Rosario, K.; Kernbach, M. E.; Gross, A. J.; Furman, B. T.; Breitbart, M.

10.1101/2023.12.11.571111 — microbiology — Posted on 2024-03-22

1507 The Relationship of pqs Gene Expression to Acylhomoserine Lactone Signaling in Pseudomonas aeruginosa

Soto-Aceves, M. P.; Smalley, N. E.; Schaefer, A. L.; Greenberg, E. P.

10.1101/2024.03.22.586172 — microbiology — Posted on 2024-03-22

1508 Intercontinental dissemination and diversification of Xanthomonas perforans in tomato production

Timilsina, S.; Iruegas-Bocardo, F.; Jibrin, M. O.; Sharma, A.; Subedi, A.; Minsavage, G. V.; Huguet-Tapia, J.; Klein-Gordon, J.; Adhikari, P.; Adhikari, T. B.; Cirvilleri, G.; Belen Tapia de la Barrera, L.; Bernal, E.; Creswell, T. C.; Doan, T. T. K.; Coutinho, T. A.; Egel, D. S.; Felix-Gastelum, R.; Francis, D. M.; Kebede, M.; Lewis Ivey, M.; Louws, F. J.; Luo, L.; Maynard, E. T.; Miller, S. A.; Nguyen, N. T. T.; Osdaghi, E.; Quezado-Duval, A. M.; Roach, R.; Rotondo, F.; Ruhl, G. E.; Shutt, V. M.; Thummabenjapone, P.; Trueman, C.; Roberts, P. D.; Jones, J. B.; Vallad, G. E.; Goss, E. M.

10.1101/2024.03.22.585974 — microbiology — Posted on 2024-03-22

1509 Interactions between Pseudomonas aeruginosa and six opportunistic pathogens cover a broad spectrum from mutualism to antagonism

Laffont, C.; Wechsler, T.; Kümmerli, R.

10.1101/2024.03.22.586229 — microbiology — Posted on 2024-03-22

1510 Adaptive evolution of sesquiterpene deoxyphomenone in mycoparasitism by Hansfordia pulvinata associated with horizontal gene transfer from Aspergillus species

Maeda, K.; Sumita, T.; Nishi, O.; Sushida, H.; Higashi, Y.; Nakagawa, H.; Suzuki, T.; Iwao, E.; Fanani, M. Z.; Nishiya, Y.; Iida, Y.

10.1101/2024.03.22.586281 — microbiology — Posted on 2024-03-22

1511 Feather degradation in Stenotrophomonas maltophilia relies on conversion and internalization of keratin monomer

Cao, Z.; Song, X.; Xue, K.; Zhang, W.; Zhang, Y.; Chen, T.; Zhang, X.-Q.

10.1101/2024.03.22.586301 — microbiology — Posted on 2024-03-22

1512 Electroantennography Responses of African Meliponine Bee Species (Hymenoptera: meliponini) to Hetero-Specific Trail Pheromones: Glandular Sequestration of Terpenyl Esters .

Bobadoye, B.; Nganso, B.; Kiatoko, N.

10.1101/2024.03.19.585691 — zoology — Posted on 2024-03-22

1513 Higher prevalence of sacbrood virus in highbush blueberry pollination units

McAfee, A.; French, S. K.; Tsvetkov, N.; Higo, H.; Common, J.; Pernal, S. F.; Giovenazzo, P.; Hoover, S. E.; Guzman-Novoa, E.; Currie, R. W.; Veiga, P. W.; Conflitti, I. M.; Pepinelli, M.; Tran, L.; Zayed, A.; Guarna, M. M.; Foster, L. J.

10.1101/2024.03.20.585971 — zoology — Posted on 2024-03-22

1514 Functional characterization of fatty acid synthase in Hermetia illucens

Jiang, Y.; Xue, W.; Peng, Z.; Hou, P.; Kou, Z.; Chen, B.; Lu, H.; Huang, Y.

10.1101/2024.03.22.586266 — synthetic biology — Posted on 2024-03-22

1515 Genetic designs for stochastic and probabilistic biocomputing

Grozinger, L.; Miro-Bueno, J.; Goni-Moreno, A.

10.1101/2024.03.22.586310 — synthetic biology — Posted on 2024-03-22

1516 MOSAIC: a highly efficient, one-step recombineering approach to plasmid editing and diversification

van den Brink, M.; Althuis, T. Y.; Danelon, C.; Claassens, N. J.

10.1101/2024.03.22.586135 — synthetic biology — Posted on 2024-03-22

1517 Synthetic genome modules designed for programmable silencing of functions and chromosomes

Lu, X.; Shaw, W. M.; Sutradhar, A.; Stracquadanio, G.; Ellis, T.

10.1101/2024.03.22.586311 — synthetic biology — Posted on 2024-03-22

1518 Both major xanthophyll cycles present in nature can provide Non-Photochemical Quenching in the model diatom Phaeodactylum tricornutum

Giossi, C. E.; Wünsch, M. A.; Dautermann, O.; Schober, A. F.; Buck, J. M.; Kroth, P. G.; Lohr, M.; Lepetit, B.

10.1101/2024.03.19.584964 — plant biology — Posted on 2024-03-22

1519 Evaluation of Octopus maya enzyme activity of the digestive gland and gastric juice

Pineda-Suazo, D.; Escobedo Hinojosa, W.; Fabian Canseco, L. E.; Gallardo, P.; Moguel Ojeda, C.; Caamal Monsreal, C.; Sanchez Arteaga, A.; Rosas, C.

10.1101/2024.03.19.585784 — physiology — Posted on 2024-03-22

1520 The remarkable similarity in the serum proteome between type 2 diabetics and controls

Mosedale, D. E.; Sharp, T.; de Graff, A.; Grainger, D.

10.1101/2024.03.19.585746 — pathology — Posted on 2024-03-22

1521 A TLR4 ligand-based adjuvant for promoting the immunogenicity of Typhoid subunit vaccines

Alugupalli, K. R.

10.1101/2024.03.22.581918 — immunology — Posted on 2024-03-22

1522 V1 receptive field structure contributes to neuronal response latency

Vafaei, A.; Mohammadi, M.; Khadir, A.; Zabeh, E.; YazdaniBanafsheDaragh, F.; Khorasani, M.; Lashgari, R.

10.1101/2021.12.30.474591 — neuroscience — Posted on 2024-03-22

1523 Forage conservation is a neglected source of nitrous oxide

Yang, S.; Mahmood, M.; Baral, R.; Wu, H.; Almloff, M.; Stanton, L.; Min, D.; Smiley, B.; Liams, C.; Yu, J.; Im, J.

10.1101/2024.03.19.585631 — bioengineering — Posted on 2024-03-22

1524 Engineering Tumor Stroma Morphogenesis Using Dynamic Cell-Matrix Spheroid Assembly

Buckenmeyer, M. J.; Brooks, E. A.; Taylor, M. S.; Yang, L.; Holewinski, R. J.; Meyer, T. J.; Galloux, M.; Garmendia-Cedillos, M.; Pohida, T. J.; Andresson, T.; St. Croix, B.; Wolf, M. T.

10.1101/2024.03.19.585805 — bioengineering — Posted on 2024-03-22

1525 Combining Top-Down and Bottom-Up: An Open Microfluidic Microtumor Model for Investigating Tumor Cell-ECM Interaction and Anti-Metastasis

Li, C.; Li, J.; Argall-Knapp, Z.; Hendrikse, N. W.; Farooqui, M. A.; Raykowski, B.; King, A.; Nong, S.

10.1101/2024.03.19.585776 — bioengineering — Posted on 2024-03-22

1526 Activity of zebrafish THAP9 transposase and zebrafish P element-like transposons

Kutnowski, N.; Ghanim, G. E.; Lee, Y.; Rio, D.

10.1101/2024.03.22.586318 — biochemistry — Posted on 2024-03-22

1527 Paradigm shift in biomarker translation: a pipeline to generate clinical grade biomarker candidates from DIA-MS discovery

Fu, Q.; Vegesna, M.; Sundararaman, N.; Damoc, E.; Arrey, T. N.; Pashkova, A.; Mengesha, E.; Debbas, P.; Joung, S.; Li, D.; Cheng, S.; Braun, J.; McGovern, D. P. B.; Murray, C.; Xuan, Y.; Van Eyk, J. E.

10.1101/2024.03.20.586018 — biochemistry — Posted on 2024-03-22

1528 A PTER-dependent pathway of taurine metabolism linked to energy balance

Wei, W.; Lyu, X.; Markhard, A. L.; Fu, S.; Mardjuki, R. E.; Cavanagh, P. E.; Zeng, X.; Rajniak, J.; Lu, N.; Xiao, S.; Zhao, M.; Dolores Moya-Garzon, M.; Truong, S. D.; Chou, C. J.; Wat, L. W.; Chidambaranathan Reghupaty, S.; Voilquin, L.; Xu, D.; Shen, F.; Huang, W.; Ramirez, C. B.; Jang, C.; Svensson, K. J.; Fischbach, M. A.; Long, J. Z.

10.1101/2024.03.21.586194 — biochemistry — Posted on 2024-03-22

1529 Deletion of arrestin-3 does not improve compulsive drug- seeking behavior in a longitudinal paradigm of oral morphine self-administration

Gooding, S.; Felth, L.; Foxall, R.; Rosa, Z.; Sall, I. J.; Gaur, A.; Ireton, K.; Gipoor, J.; King, M.; Dirks, N.; Whistler, C. A.; Whistler, J. A.

10.1101/2023.03.30.534994 — animal behavior and cognition — Posted on 2024-03-22

1530 Epigenetic and evolutionary mechanisms uniquely contribute to rescue from global change

Brennan, R.; deMayo, J.; Finiguerra, M.; Baumann, H.; Dam, H. G.; Pespeni, M.

10.1101/2024.03.20.585843 — evolutionary biology — Posted on 2024-03-22

1531 Reconstructing the dynamics of past coral endosymbiotic algae communities using coral ancient DNA (coraDNA)

Rey, O.; Dissard, D.; Toulza, E.; Guinebert, T.; Saccas, M.; Allienne, J.-F.; Butscher, J.; Zoubir, M. B.; Iwankow, G.; Tougard, C.; Vidal-Dupiol, J.

10.1101/2024.03.21.584420 — evolutionary biology — Posted on 2024-03-22

1532 Plant species richness and the root economics space drive soil fungal communities

Hennecke, J.; Bassi, L.; Albracht, C.; Amyntas, A.; Bergmann, J.; Eisenhauer, N.; Fox, A.; Heimbold, L.; Kuyper, T.; Lange, M.; Alves de Souza, Y. P.; Rai, A.; Solbach, M. D.; Mommer, L.; Weigelt, A.

10.1101/2024.03.20.585751 — ecology — Posted on 2024-03-22

1533 Stand structure as the proximate driver of endemic biodiversity and ecosystem functions in tropical mosaic landscapes

Rajaonarimalala, R.; Korol, Y.; Andrianarimisa, A.; Dröge, S.; Fulgence, T. R.; Grass, I.; Kreft, H.; Osen, K.; Rakotomalala, A. A. N. A.; Rakouth, B.; Ranarijaona, H. L. T.; Randriamanantena, R.; Ratsoavina, F. M.; Ravaomanarivo, L. H. R.; Raveloaritiana, E.; Schwab, D.; Soazafy, M. R.; Tscharntke, T.; Wurz, A.; Hölscher, D.; Martin, D. A.

10.1101/2024.03.20.582692 — ecology — Posted on 2024-03-22

1534 What do we know about the missing millions of Earths insect species and can we improve their collection: evidence from bark beetles?

Stork, N. E.; Boyle, M. J. W.; Wardhaugh, C.; Beaver, R.

10.1101/2024.03.20.585838 — ecology — Posted on 2024-03-22

1535 Allele-specific CRISPR/Cas9 editing inactivates a single nucleotide variant associated with collagen VI muscular dystrophy

Bolduc, V.; Sizov, K.; Brull, A.; Esposito, E.; Chen, G. S.; Uapinyoying, P.; Sarathy, A.; Johnson, K.; Bonnemann, C. G.

10.1101/2024.03.22.586265 — molecular biology — Posted on 2024-03-22

1536 Mar1, an HMG-box protein, regulates n-alkane adsorption and cell morphology of the dimorphic yeast Yarrowia lipolytica

Kimura-Ishimaru, C.; Liang, S.; Matsuse, K.; Iwama, R.; Sato, K.; Watanabe, N.; Tezaki, S.; Horiuchi, H.; Fukuda, R.

10.1101/2024.03.22.586302 — microbiology — Posted on 2024-03-22

1537 The AusAB non-ribosomal peptide synthase in Staphylococcus aureus preferentially incorporates exogenous phenylalanine and tyrosine into the aureusimine natural products

Moldovan, A.; Krischke, M.; Huber, C.; Hans, C.; Mueller, M. J.; Eisenreich, W.; Rudel, T.; Fraunholz, M.

10.1101/2024.03.22.586303 — microbiology — Posted on 2024-03-22

1538 Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase in prokaryotes

Wang, Y.; Wang, G.; Zhang, L.; Cai, Q.; Lin, M.; Huang, D.; Xie, Y.; Lin, W.; Lin, X.

10.1101/2024.03.22.586220 — microbiology — Posted on 2024-03-22

1539 Exploring variations in lipids among drug-resistant and sensitive Mycobacterium tuberculosis by Thin layer chromatography and mass spectrometry

Kumar, K.; Giribhattanavar, P.; Sagar, C. B. K.; Patil, S. A.

10.1101/2024.03.22.586225 — microbiology — Posted on 2024-03-22

1540 High-resolution scRNA-seq reveals genomic determinants of antigen expression hierarchy in African Trypanosomes

McWilliam, K. R.; Keneskhanova, Z.; Cosentino, R. O.; Dobrynin, A.; Smith, J. E.; Subota, I.; Mugnier, M. R.; Colome-Tatche, M.; Siegel, T. N.

10.1101/2024.03.22.586247 — microbiology — Posted on 2024-03-22

1541 Neutralisation sensitivity of the SARS-CoV-2 BA.2.87.1 variant

Sheward, D. J.; Marking, U.; Bladh, O.; Held, S.; Looyens, E.; Vandenabeele, L.; Muschiol, S.; Aguilera, K.; Norin, N. G.; Oling, S.; Westerberg, M.; Martin, D.; Hedestam, G. B. K.; Albert, J.; Thalin, C.; Murrell, B.

10.1101/2024.03.21.586176 — immunology — Posted on 2024-03-22

1542 Design of Antigen-Specific Antibody CDRH3 Sequences Using AI and Germline-Based Templates

Marinov, T. M.; Abu-Shmais, A.; Janke, A. K.; Georgiev, I.

10.1101/2024.03.22.586241 — immunology — Posted on 2024-03-22

1543 Antigen-driven CD8+ T cell clonal expansion is a prominent feature of MASH in humans and mice.

Burtis, A. E.; DeNicola, D. M.; Ferguson, M. E.; Santos, R. G.; Pinilla, C.; Kriss, M. S.; Orlicky, D. J.; Tamburini, B. A. J.; Gillen, A. E.; Burchill, M. A.

10.1101/2024.03.20.583964 — immunology — Posted on 2024-03-22

1544 Senolytic CAR T cells reverse aging-associated defects in intestinal regeneration and fitness

Eskiocak, O.; Chowdhury, S.; Shah, V.; Nnuji-John, E.; Chung, C.; Boyer, J. A.; Harris, A. S.; Habel, J.; Sadelain, M.; Beyaz, S.; Amor, C.

10.1101/2024.03.19.585779 — cell biology — Posted on 2024-03-22

1545 An Image Quality Transfer Technique for Localising Deep Brain Stimulation Targets

Zheng, Y.-Q.; Akram, H.; Li, Z.; Smith, S.; Jbabdi, S.

10.1101/2024.03.18.584979 — neuroscience — Posted on 2024-03-22

1546 Adherens junctions limit the extent of the septate junctions in Drosophila midgut enterocytes but are not required for apical-basal polarity

Carvalho, C. A.; Tame, M. A.; St Johnston, D.

10.1101/2024.03.22.586295 — cell biology — Posted on 2024-03-22

1547 APP and its intracellular domain modulate Alzheimers disease risk gene networks in transgenic APPsw and PSEN1M146I porcine models

Habekost, M.; Poulsen, E.; Enghild, J. J.; Denham, M.; Joergensen, A. L.; Qvist, P.

10.1101/2024.03.21.585176 — cell biology — Posted on 2024-03-22

1548 Adaptive Optics in an Oblique Plane Microscope

McFadden, C.; Marin, Z.; Chen, B.; Daetwyler, S.; Wang, X.; Rajendran, D.; Fiolka, R. P.

10.1101/2024.03.21.586191 — cell biology — Posted on 2024-03-22

1549 Loss of KIF13B causes time-dependent changes in ciliary polycystin-2 levels and extracellular vesicle release

Rezi, C. K.; Frei, A.; Campestre, F.; Berggreen, C. R.; Laplace, J.; Sicot, A.; Li, G.; Johansen, S. L.; Sorensen, J. K. T.; Berchtold, M. W.; Chamlali, M.; Christensen, S. T.; Boldt, K.; Anvarian, Z.; May-Simera, H. L.; Pedersen, L. B.

10.1101/2024.03.21.586066 — cell biology — Posted on 2024-03-22

1550 A Novel Method to Visualize Active Small GTPases Unveils Distinct Sites of Sar1 Activation During Collagen Secretion.

Maeda, M.; Arakawa, M.; Komatsu, Y.; Saito, K.

10.1101/2024.03.20.586037 — cell biology — Posted on 2024-03-22

1551 Human CCDC51 and yeast Mdm33 are functionally conserved mitochondrial inner membrane proteins that demarcate a subset of organelle fission events

Edington, A. R.; Connor, O. M.; Marlar-Pavey, M.; Friedman, J. R.

10.1101/2024.03.21.586162 — cell biology — Posted on 2024-03-22

1552 Space-time dynamics of genome replication studied with super-resolved microscopy

Gelleri, M.; Sterr, M.; Strickfaden, H.; Cremer, C.; Cremer, T.; Cremer, M.

10.1101/2024.03.22.586000 — cell biology — Posted on 2024-03-22

1553 Combination of AID2 and BromoTag expands the utility of degron-based protein knockdowns

Hatoyama, Y.; Islam, M.; Bond, A. G.; Hayashi, K.-I.; Ciulli, A.; Kanemaki, M. T.

10.1101/2024.03.20.586026 — cell biology — Posted on 2024-03-22

1554 Reduced PaxillinB localization to cell-substrate adhesions promotes cell migration in Dictyostelium

Fierro Morales, J. C.; Roh-Johnson, M.; Titus, M. A.; Redfearn, C.

10.1101/2024.03.19.585764 — cell biology — Posted on 2024-03-22

1555 A constricted mitochondrial morphology optimizes respiration.

Singh, M. K.; Cavellini, L.; Kunz, C.; Lelek, M.; Bomme, P.; Belgareh-Touze, N.; Mallet, A.; Dietrich, L.; Zimmer, C.; Cohen, M. M.

10.1101/2024.03.21.582105 — cell biology — Posted on 2024-03-22

1556 Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter

Baker, G. J.; Novikov, E.; Zhao, Z.; Vallius, T.; Davis, J. A.; Lin, J.-R.; Muhlich, J. L.; Mittendorf, E. A.; Santagata, S.; Guerriero, J. L.; Sorger, P. K.

10.1101/2023.11.01.565120 — pathology — Posted on 2024-03-22

1557 Decoding Phase Separation of Prion-Like Domains through Data-Driven Scaling Laws

Maristany, M. J.; Aguirre Gonzalez, A.; Espinosa, J. R.; Huertas, J.; Collepardo-Guevara, R.; Joseph, J. A.

10.1101/2023.06.14.543914 — biophysics — Posted on 2024-03-22

1558 ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

Thayer, M. J.; Heskett, M. B.; Smith, L. G.; Spellman, P. T.; Yates, P. A.

10.1101/2022.06.04.494840 — genetics — Posted on 2024-03-22

1559 Testing the mettle of METAL: A comparison of phylogenomic methods using a challenging but well-resolved phylogeny

Braun, E. L.; Oliveros, C. H.; White Carreiro, N. D.; Zhao, M.; Glenn, T. C.; Brumfield, R. T.; Braun, M. J.; Kimball, R. T.; Faircloth, B. C.

10.1101/2024.02.28.582627 — evolutionary biology — Posted on 2024-03-22

1560 DNA Double-Strand Break Movement in Heterochromatin Depends on the Histone Acetyltransferase dGcn5.

Kendek, A.; Sandron, A.; Lambooij, J.-P.; Colmenares, S. U.; Pociunaite, S. M.; Gooijers, I.; de Groot, L.; Karpen, G.; Janssen, A.

10.1101/2023.11.30.569406 — cell biology — Posted on 2024-03-22

1561 Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway

Hershkovitz, D.; Chen, E. J.; Ensminger, A. W.; Dugan, A. S.; Joyce, A. C.; Segal, G.; Isberg, R. R.

10.1101/2024.03.17.585421 — microbiology — Posted on 2024-03-22

1562 Single cell transcriptomics of vomeronasal neuroepithelium reveals a differential endoplasmic reticulum environment amongst neuronal subtypes

G V S, D.; Terasaki, M.; Dani, A.

10.1101/2024.01.08.574704 — neuroscience — Posted on 2024-03-22

1563 Transcriptional modulation unique to vulnerable motor neurons predict ALS across species and SOD mutations

Mei, I.; Nichterwitz, S.; Leboeuf, M.; Nijssen, J.; Lenoel, I.; Repsilber, D.; Lobsiger, C. S.; Hedlund, E.

10.1101/2024.03.15.584775 — neuroscience — Posted on 2024-03-22

1564 Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice

Saenz de Miera, C.; Bellefontaine, N.; Allen, S. J.; Myers, M. G.; Elias, C. F.

10.1101/2023.09.21.558865 — neuroscience — Posted on 2024-03-22

1565 Eye-movement artifact correction in infant EEG

Srishyla, D.; Webb, S.; Elsabbagh, M.; O'Reilly, C.; BASIS team, Center for Brain and Cognitive Development, London,UK,

10.1101/2024.03.19.585723 — neuroscience — Posted on 2024-03-22

1566 Asymmetric Fin Shape changes Swimming Dynamics of Ancient Marine Reptiles' Soft Robophysical Models

Sprumont, H.; Allione, F.; Schwab, F.; Wang, B.; Mucingat, C.; Lunati, I.; Scheyer, T.; Ijspeert, A.; Jusufi, A.

10.1101/2024.02.15.580532 — biophysics — Posted on 2024-03-22

1567 Contrasting Sequence with Structure: Pre-training Graph Representations with PLMs

Robinson, L. C. B.; Atkinson, T.; Copoiu, L.; Bordes, P.; Pierrot, T.; Barrett, T.

10.1101/2023.12.01.569611 — bioinformatics — Posted on 2024-03-22

1568 Analyzing single-cell bisulfite sequencing data with MethSCAn

Kremer, L. P.; Braun, M.; Ovchinnikova, S.; Kuechenhoff, L.; Cerrizuela, S.; Martin-Villalba, A.; Anders, S.

10.1101/2022.06.15.496318 — bioinformatics — Posted on 2024-03-22

1569 Assessing NGS-based computational methods for predicting transcriptional regulators with query gene sets

Lu, Z.; Xiao, X.; Zheng, Q.; Wang, X.; Xu, L.

10.1101/2024.02.01.578316 — bioinformatics — Posted on 2024-03-22

1570 A snakemake toolkit for the batch assembly, annotation, and phylogenetic analysis of mitochondrial genomes and ribosomal genes from genome skims of museum collections.

White, O.; Hall, A.; Price, B. W.; Williams, S.; Clark, M. D.

10.1101/2023.08.11.552985 — bioinformatics — Posted on 2024-03-22

1571 Targeted metagenomics using probe capture detect a larger diversity of nitrogen and methane cyclinggenes in complex microbial communities than traditional metagenomics

Siljanen, H. M. P.; Manoharan, L.; Hilts, A. S.; Bagnoud, A.; Alves, R. J. E.; Jones, C. M.; Kerou, M.; Sousa, F.; Hallin, S.; Biasi, C.; Schleper, C.

10.1101/2022.11.04.515048 — microbiology — Posted on 2024-03-22

1572 Building compositional tasks with shared neural subspaces

Tafazoli, S.; Bouchacourt, F.; Ardalan, A.; Markov, N. T.; Uchimura, M.; Gomes Mattar, M. G.; Daw, N. D.; Buschman, T. J.

10.1101/2024.01.31.578263 — neuroscience — Posted on 2024-03-22

1573 Longitudinal trajectories of the neural encoding mechanisms of speech-sound features during the first year of life

Puertollano, M.; Ribas-Prats, T.; Gorina-Careta, N.; Ijjou-Kadiri, S.; Arenillas-Alcon, S.; Mondejar-Segovia, A.; Gomez-Roig, M. D.; Escera, C.

10.1101/2023.11.24.567803 — neuroscience — Posted on 2024-03-22

1574 EnhancerNet: a model for enhancer selection in dense regulatory networks recapitulates the dynamics of cell type acquisition

Karin, O.

10.1101/2024.02.03.578744 — systems biology — Posted on 2024-03-22

1575 The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function

Kohnle, C.; Koziarek, S.; Warwick, T.; Theodorou, K.; Fischer, A.; Juni, R. P.; Muhly Reinholz, M.; Busscher, D.; Lam, F.; Vetter, F.; Wagner, J. U. G.; Sommer, J.; Gimbel, A. T.; Stanicek, L.; Guenther, S.; Wittig, I.; Maegdefessel, L.; Leisegang, M. S.; Brandes, R. P.; Dimmeler, S.; Boon, R. A.

10.1101/2024.02.28.582649 — cell biology — Posted on 2024-03-22

1576 Systems analysis of miR-199a/b-5p and multiple miR-199a/b-5p targets during chondrogenesis

Patel, K.; Barter, M. J.; Soul, J.; Clark, P.; Proctor, C. J.; Clark, I. M.; Young, D.; Shanley, D. P.

10.1101/2023.03.31.535081 — systems biology — Posted on 2024-03-22

1577 Meat enriched-diet and inflammation promote PI3Kα-dependent pancreatic cell plasticity that limit tissue regeneration.

Cayron, C.; Bozoglou, D.; Villard, A. V.; Reyes-Castellanos, G.; Therville, N.; Baer, R.; Arcucci, S.; Naud, N.; Tosolini, M.; Pont, F.; Ferreira Da Mota, D.; Gueraud, F.; Basset, C.; Carrier, A.; Pierre, F.; Thibault, B.; Dufresne, M.; Guillermet-Guibert, J.

10.1101/2023.08.22.554245 — pathology — Posted on 2024-03-22

1578 In vivo targeted and deterministic single cell malignant transformation

Scerbo, P.; Tisserand, B.; Delagrange, M.; Debare, H.; Bensimon, D.; Ducos, B.

10.1101/2024.01.30.577941 — cancer biology — Posted on 2024-03-22

1579 Structure-function relationships of mucociliary clearance in the human airways

Roth, D.; Sahin, A. T.; Ling, F.; Senger, C.; Quiroz, E.; Calvert, B.; van der Does, A.; Güney, T. G.; Tepho, N.; Glasl, S.; van Schadewijk, A.; von Schledorn, L.; Olmer, R.; Kanso, E.; Nawroth, J. C.; Ryan, A. L.

10.1101/2023.12.24.572054 — biophysics — Posted on 2024-03-22

1580 So ManyFolds, So Little Time: Efficient Protein Structure Prediction With pLMs and MSAs

Barrett, T. D.; Villegas-Morcillo, A.; Robinson, L.; Gaujac, B.; Admete, D.; Saquand, E.; Beguir, K.; Flajolet, A.

10.1101/2022.10.15.511553 — bioinformatics — Posted on 2024-03-22

1581 Cryo-EM map anisotropy can be attenuated by map post-processing and a new method for its estimation

Sanchez-Garcia, R.; Gaullier, G.; Cuadra-Troncoso, J. M.; Vargas, J.

10.1101/2022.12.08.517920 — bioinformatics — Posted on 2024-03-22

1582 The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2

Longhurst, A. D.; Wang, K.; Suresh, H. G.; Ketavarapu, M.; Ward, H. N.; Jones, I. R.; Narayan, V.; Hundley, F. V.; Hassan, A. Z.; Boone, C.; Myers, C.; Shen, Y.; Ramani, V.; Andrews, B. J.; Toczyski, D. P.

10.1101/2024.03.18.585604 — molecular biology — Posted on 2024-03-22

1583 Heterochromatin dynamics during the initial stages of sexual development in Plasmodium falciparum

Nhim, S.; Tinto-Font, E.; Casas-Vila, N.; Michel-Todo, L.; Cortes, A.

10.1101/2024.03.19.585770 — microbiology — Posted on 2024-03-22

1584 Extracellular vesicles produced during fungal infection in humans are immunologically active

Rezende, C. P.; Santos, P.; Piraine, R. E. A.; Silvestrini, V. C.; Barbosa, J. C.; Valera, F. C. P.; Tamashiro, E.; Podolsky, G.; Quintana, S.; Calado, R. T.; Martinez, R.; Pacheco Fill, T.; Rodrigues, M. L.; Almeida, F.

10.1101/2024.03.20.585987 — microbiology — Posted on 2024-03-22

1585 Assessment of Antibiotic Resistance Profiles in Cultivable Coliform Organisms Isolated from Ganga River Waters Across the Upper, Middle, and Lower Ganga Stretch

Balkrishna, A.; Singh, S.; Ghosh, S.; Arya, V.; Mohini,

10.1101/2024.03.20.585858 — microbiology — Posted on 2024-03-22

1586 Bivalent COVID-19 vaccines boost the capacity of pre-existing SARS-CoV-2-specific memory B cells to cross-recognize Omicron subvariants

Fryer, H. A.; Geers, D.; Gommers, L.; Zaeck, L. M.; Tan, N. H.; Jones-Freeman, B.; Goorhuis, A.; Postma, D. F.; Visser, L. G.; Hogarth, P. M.; Koopmans, M. P. G.; GeurtsvanKessel, C. H.; O'Hehir, R. E.; van der Kuy, P. H. M.; de Vries, R. D.; van Zelm, M. C.

10.1101/2024.03.20.585861 — immunology — Posted on 2024-03-22

1587 WITHDRAWN: Dynamics of Infantile Myoclonic Encephalopathy

Verma, V.

10.1101/2024.03.10.583151 — neuroscience — Posted on 2024-03-22

1588 Cell class-specific long-range axonal projections of neurons in mouse whisker-related somatosensory cortices

Liu, Y.; Bech, P.; Tamura, K.; Delez, L. T.; Crochet, S.; Petersen, C. C.

10.1101/2024.03.21.586078 — neuroscience — Posted on 2024-03-22

1589 Emergence of neural persistence: Insights from computational modelling

Verma, V.

10.1101/2024.02.19.581018 — neuroscience — Posted on 2024-03-22

1590 GABA-ergic inhibition in human MT predicts visuo-spatial intelligence mediated by reverberation with frontal cortex

Gao, Y.; Cai, Y.-C.; Liu, D.-Y.; Yu, J.; Wang, J.; Li, M.; Xu, B.; Wang, T.; Chen, G.; Northoff, G.; Bai, R.; Song, X.

10.1101/2024.03.20.585863 — neuroscience — Posted on 2024-03-22

1591 Decreasing hearing ability does not lead to improved visual speech extraction as revealed in a neural speech tracking paradigm

Haider, C. L.; Hauswald, A.; Weisz, N.

10.1101/2024.03.13.584400 — neuroscience — Posted on 2024-03-22

1592 The transformation of sensory to perceptual braille letter representations in the visually deprived brain

Haupt, M.; Graumann, M.; Teng, S.; Kaltenbach, C.; Cichy, R. M.

10.1101/2024.02.12.579923 — neuroscience — Posted on 2024-03-22

1593 Dual action of sphinganine in the plant disease resistance to bacteria.

Huby, E.; Villaume, S.; Chemotti, C.; Dorey, S.; Cordelier, S.; Crouzet, J.; Gilliard, G.; Terryn, C.; Berquand, A.; Herrfurth, C.; Feussner, I.; Jacquard, C.; Fontaine, F.; Clement, C.; Baillieul, F.; Deleu, M.; Dhondt-Cordelier, S.

10.1101/2024.02.07.579277 — plant biology — Posted on 2024-03-22

1594 Characterizing and targeting glioblastoma neuron-tumor networks with retrograde tracing

Tetzlaff, S. K.; Reyhan, E.; Bengtson, C. P.; Schroers, J.; Wagner, J.; Schubert, M. C.; Layer, N.; Puschhof, M. C.; Faymonville, A. J.; Drewa, N.; Pramatarov, R. L.; Wissmann, N.; Alhalabi, O.; Heuer, A.; Sivapalan, N.; Campos, J.; Boztepe, B.; Scheck, J. G.; Villa, G.; Schröter, M.; Sahm, F.; Forsberg-Nilsson, K.; Breckwoldt, M. O.; Acuna, C.; Suchorska, B.; Heiland, H. D.; Saez-Rodriguez, J.; Venkataramani, V.

10.1101/2024.03.18.585565 — cancer biology — Posted on 2024-03-22

1595 How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.

Ahmed, Z.; Mosabbir, W.; Tandon, D.; Pereira, S. P.; Cheema, U.; Loizidou, M.; Withington, J.; Moore, C.; Okoli, U.; Heavey, S.

10.1101/2024.03.20.585982 — cancer biology — Posted on 2024-03-22

1596 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin

Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Zheng, Q.

10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-22

1597 Contribution of the epididymis beyond fertilization: relevance of CRISP1 and CRISP3 for sperm DNA integrity and early embryo development

Sulzyk, V.; Curci, L.; Gonzalez, L. N.; Rebagliati Cid, A.; Weigel Munoz, M.; Cuasnicu, P. S.

10.1101/2024.03.19.585807 — developmental biology — Posted on 2024-03-22

1598 Interactions of netrin-1 through its glycosylation sites immobilize Deleted in Colorectal Cancer (DCC) by favoring its constitutive clustering

Uriot, K.; Blanc, O.; Auduge, N.; Faklaris, O.; Chaverot, N.; Bloch, E.; Borghi, N.; Coppey-Moisan, M.; Girard, P. P.

10.1101/2023.10.26.563740 — cell biology — Posted on 2024-03-22

1599 Atlas of Fshr Expression from Novel Reporter Mice

Chen, H.-Q.; Fang, H.; Liu, J.-T.; Chang, S.-Y.; Cheng, L.-B.; Sun, M.-X.; Feng, J.-R.; Liu, Z.; Zhang, Y.; J. Rosen, C.; Liu, P.

10.1101/2023.11.05.565707 — cell biology — Posted on 2024-03-22

1600 Septin filament assembly assists the lateral organization of membranes

El Alaoui, F.; Al-Akiki, I.; Ibanes, S.; Lyonnais, S.; Sanchez-Fuentes, D.; Desgarceaux, R.; Cazevieille, C.; Blanchard, M.-P.; PARMEGGIANI, A.; Carretero-Genevrier, A.; Piatti, S.; Picas, L.

10.1101/2024.03.19.585775 — cell biology — Posted on 2024-03-22

1601 A chromosome-level, haplotype-resolved genome assembly and annotation for the Eurasian minnow (Leuciscidae - Phoxinus phoxinus) provide evidence of haplotype diversity

Oriowo, T. O.; Chrysostomakis, I.; Martin, S.; Kukowka, S.; Brown, T.; Winkler, S.; Myers, E. W.; Boehne, A.; Stange, M.

10.1101/2023.11.30.569369 — genomics — Posted on 2024-03-22

1602 Dynamics of brainstem arousal systems and pupil size predict cortical interactions for flexible decision-making

van den Brink, R. L.; Hagena, K.; Wilming, N.; Murphy, P. R.; Calder-Travis, J.; Finsterbusch, J.; Büchel, C.; Donner, T. H.

10.1101/2023.12.05.570327 — neuroscience — Posted on 2024-03-22

1603 Performance comparison of high throughput single-cell RNA-Seq platforms in complex tissues

Colino Sanguino, Y.; Rodriguez de la Fuente, L.; Gloss, B.; Law, A. M.; Handler, K.; Pajic, M.; Salomon, R.; Gallego Ortega, D.; Valdes Mora, F.

10.1101/2023.04.04.535585 — genomics — Posted on 2024-03-22

1604 Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers

Oo, J. A.; Warwick, T.; Palfi, K.; McNicoll, F.; Cao, C.; Prieto-Garcia, C.; Zhou, Y.; Gavrilov, A. A.; Razin, S. V.; Lam, F.; Günther, S.; Cabrera-Orefice, A.; Wittig, I.; Pullamsetti, S. S.; Kurian, L.; Gilsbach, R.; Schulz, M. H.; Dikic, I.; Müller-McNicoll, M.; Brandes, R. P.; Leisegang, M. S.

10.1101/2024.03.21.585172 — molecular biology — Posted on 2024-03-22

1605 Exploring anterior thalamus functional connectivity with cortical regions in prospective memory with ultra-high field fMRI

Flanagan, L.; Mansur, B. d. M.; Reichert, C.; Richter, A.; Golbabaei, S.; Kizilirmak, J. M.; Sweeney-Reed, C. M.

10.1101/2024.02.14.580346 — neuroscience — Posted on 2024-03-22

1606 Penalised regression improves imputation of cell-type specific expression using RNA-seq data from mixed cell populations compared to domain-specific methods

Lin, W.-Y.; Kartawinata, M.; Jebson, B. R.; Restuadi, R.; CLUSTER Consortium, ; Wedderburn, L. R.; Wallace, C.

10.1101/2023.09.11.556650 — bioinformatics — Posted on 2024-03-22

1607 Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre

Bao, L.; Liljeruhm, J.; Crespo Blanco, R.; Brandis, G.; Remme, J.; Forster, A. C.

10.1101/2024.03.21.586085 — biochemistry — Posted on 2024-03-22

1608 Wnt-Ror-Dvl signalling and the dystrophin complex organize planar-polarized membrane compartments in C. elegans muscles

Peysson, A.; Zariohi, N.; Gendrel, M.; Chambert-Loir, A.; Frebault, N.; Cheynet, E.; Andrini, O.; Boulin, T.

10.1101/2023.03.28.534519 — cell biology — Posted on 2024-03-22

1609 Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells

Yao, Y.; Lou, X.; Jin, L.; Liu, J.; Chen, Y.; Cheng, S.; Zhao, T.; Ke, S.; Zhang, L.; Xu, Y.; He, L.; Li, H.

10.1101/2023.08.03.551799 — cell biology — Posted on 2024-03-22

1610 Plasmid partitioning driven by collective migration of ParA between nucleoid lobes

Köhler, R.; Murray, S. M.

10.1101/2023.10.16.562490 — microbiology — Posted on 2024-03-22

1611 Two structurally different oomycete lipophilic MAMPs induce distinctive plant immune responses.

Monjil, M. S.; Kato, H.; Ota, S.; Matsuda, K.; Suzuki, N.; Tenhiro, S.; Tatsumi, A.; Pring, S.; Miura, A.; Camagna, M.; Suzuki, T.; Tanaka, A.; Terauchi, R.; Sato, I.; Chiba, S.; Kawakita, K.; Ojika, M.; Takemoto, D.

10.1101/2021.10.22.465218 — plant biology — Posted on 2024-03-22

1612 Screening of associated bacteria of Alexandrium catenella on affecting PSTs production and influence mechanism

Zou, S.; Yu, X.; Sun, T.; Wei, L.; Wu, X.

10.1101/2024.01.31.578139 — ecology — Posted on 2024-03-22

1613 Imaging genomics reveals genetic architecture of the globular human braincase

Molz, B.; Eising, E.; Alagoz, G.; Schijven, D.; Francks, C.; Gunz, P.; Fisher, S. E.

10.1101/2024.03.20.585712 — genetics — Posted on 2024-03-22

1614 The L-lactate dehydrogenases of Pseudomonas aeruginosa are conditionally regulated but both contribute to survival during macrophage infection

Florek, L. C.; Lin, X.; Lin, Y.-C.; Chakraborty, A.; Lin, M.-H.; Price-Whelan, A.; Tong, L.; Rahme, L.; Dietrich, L. E. P.

10.1101/2024.03.21.586142 — microbiology — Posted on 2024-03-22

1615 Neural dynamics express syntax in the time domain during natural story listening

Coopmans, C. W.; de Hoop, H.; Tezcan, F.; Hagoort, P.; Martin, A. E.

10.1101/2024.03.19.585683 — neuroscience — Posted on 2024-03-22

1616 Kif7 deletion in a mouse model of human ciliopathy alters cerebral cortex development

PEDRAZA, M.; GRAMPA, V.; PUECH, J.; SCOTTO-LOMASSESE, S.; MUZERELLE, A.; MOHAMMAD, A.; RENIER, N.; METIN, C.; MASSON, J.

10.1101/2024.03.21.586159 — neuroscience — Posted on 2024-03-22

1617 Preeclamptic phenotype in transgenic mice with fetuses carrying APOL1 risk variants

Yoshida, T.; Latt, K. Z.; Shrivastav, S.; Lu, H.; Reidy, K. J.; Charlton, J. R.; Zhao, Y.; Winkler, C. A.; Reznik, S. E.; Rosenberg, A. Z.; Kopp, J. B.

10.1101/2024.03.20.586039 — molecular biology — Posted on 2024-03-21

1618 An essential and highly selective protein import pathway encoded by nucleus-forming phage

Morgan, C. J.; Enustun, E.; Armbruster, E. G.; Birkholz, E. A.; Prichard, A.; Forman, T.; Aindow, A.; Wannasrichan, W.; Peters, S.; Inlow, K.; Shepherd, I. L.; Razavilar, A.; Chaikeeratisak, V.; Adler, B. A.; Cress, B. F.; Doudna, J. A.; Pogliano, K.; Villa, E.; Corbett, K. D.; Pogliano, J.

10.1101/2024.03.21.585822 — microbiology — Posted on 2024-03-21

1619 Hepatitis B Virus genomes associate with cellular sites of DNA damage by inducing replication stress

Marcoe, G. J.; Larsen, C. I. S.; Majumder, K.

10.1101/2024.03.21.586072 — microbiology — Posted on 2024-03-21

1620 In Vitro Efficacy of Next Generation Dihydrotriazines and Biguanides Against Babesiosis and Malaria Parasites

Vydyam, P.; Chand, M.; Gihaz, S.; Renard, I.; Heffernan, G. D.; Jacobus, L. R.; Jacobus, D. P.; Saionz, K. W.; Shah, R.; Shieh, H.-M.; Terpinski, J.; Zhao, W.; Cornillot, E.; Ben Mamoun, C.

10.1101/2024.03.20.585986 — microbiology — Posted on 2024-03-21

1621 The gases H2 and O2 in open-culture reactors influence the performance and microbiota of chain elongation into n-caproate and n-caprylate.

Spirito, C. M.; Lucas, T. N.; Patz, S.; Jeon, B. S.; Werner, J. J.; Trondsen, L. H.; Guzman, J. J.; Huson, D. H.; Angenent, L. T.

10.1101/2024.03.21.586105 — microbiology — Posted on 2024-03-21

1622 Glyphosate Effects on Growth and Biofilm Formation in Bee Gut Symbionts and Diverse Associated Bacteria

Motta, E. V. S.; De Jong, T. K.; Gage, A.; Edwards, J. A.; Moran, N. A.

10.1101/2024.03.20.585985 — microbiology — Posted on 2024-03-21

1623 Bioinformatic prediction and high throughput in vivo screening to identify cis-regulatory elements for the development of algal synthetic promoters

Torres-Tiji, Y.; Sethuram, H.; Gupta, A.; McCauley, J.; Dutra-Molino, J.-V.; Pathania, R.; Saxton, L.; Kang, K.; Hillson, N. J.; Mayfield, S. P.

10.1101/2024.03.20.585996 — synthetic biology — Posted on 2024-03-21

1624 Development of radiofluorinated MLN-4760 derivatives for PET imaging of the SARS-CoV-2 entry receptor ACE2

Wang, J.; Beyer, D.; Vaccarin, C.; He, Y.; Tanriver, M.; Benoit, R. M.; Deupi, X.; Mu, L.; Bode, J. W.; Schibli, r.; Mueller, C.

10.1101/2024.03.20.585792 — pharmacology and toxicology — Posted on 2024-03-21

1625 Estimating Nutrient Concentration in Food Using Untargeted Metabolomics

Sebek, M. L.; Menichetti, G.; Barabasi, A.-L.

10.1101/2022.12.02.518912 — biochemistry — Posted on 2024-03-21

1626 Shared Transcriptomic Signatures of Inflammaging Among Diverse Strains of Drosophila melanogaster

Perna, S. I.; Tang, W.; Blimbaum, S. D.; Li, A. Y.; Zhou, L.

10.1101/2024.01.17.576061 — immunology — Posted on 2024-03-21

1627 Delineating redox cooperativity in water-soluble and membrane multiheme cytochromes through protein design

Hardy, B. J.; Dubiel, P.; Bungay, E. L.; Rudin, M.; Williams, C.; Arthur, C. J.; Guberman-Pfeffer, M. J.; Oliveira, A. S. F.; Curnow, P.; Anderson, J. L. R.

10.1101/2024.03.21.586059 — biochemistry — Posted on 2024-03-21

1628 PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes

Singh, S.; Dransfeld, U.; Ambaw, Y.; Lopez-Scarim, J.; Farese, R. V.; Walther, T. C.

10.1101/2024.03.21.586175 — biochemistry — Posted on 2024-03-21

1629 Asynchronous microexon splicing of LSD1 and PHF21A during neurodevelopment

Nagai, M.; Porter, R. S.; Hughes, E.; Saunders, T.; Iwase, S.

10.1101/2024.03.21.586181 — biochemistry — Posted on 2024-03-21

1630 Discovery and chemical optimisation of a Potent, Bi-cyclic (Bicycle(R)) Antimicrobial Inhibitor of Escherichia coli PBP3

Rowland, C. E.; Newman, H.; Martin, T. T.; Dods, R.; Bournakas, N.; Wagstaff, J. M.; Lewis, N.; Stanway, S. J.; Balmforth, M.; Kessler, C.; van Rietschoten, K.; Bellini, D.; Roper, D. I.; Lloyd, A. J.; Dowson, C. G.; Skynner, M. J.; Beswick, P.; Dawson, M. J.

10.1101/2024.03.20.581580 — biochemistry — Posted on 2024-03-21

1631 Translational impacts of enzymes that modify ribosomal RNA around the peptidyl transferase centre

Bao, L.; Liljeruhm, J.; Crespo Blanco, R.; Brandis, G.; Remme, J.; Forster, A. C.

10.1101/2024.03.21.586085 — biochemistry — Posted on 2024-03-21

1632 Redirecting the pioneering function of FOXA1 with covalent small molecules

Won, S. J.; Zhang, Y.; Reinhardt, C. J.; MacRae, N. S.; DeMeester, K. E.; Njomen, E.; Hargis, L. M.; Remsberg, J. R.; Melillo, B.; Cravatt, B. F.; Erb, M. A.

10.1101/2024.03.21.586158 — biochemistry — Posted on 2024-03-21

1633 RNA Chemical Probing Reagents and Protein Amino Acids: a Double-Edged Sword

Fallon, L.; Klingler, D.; Cohn, D.; Marcus, L.; Jones, A. N.

10.1101/2024.03.21.586119 — biochemistry — Posted on 2024-03-21

1634 Structural insight into bacterial co-transcriptional translation initiation

Yokoyama, T.; Murayama, Y.; Uchikubo-Kamo, T.; Tomabechi, Y.; Nagao, A.; Suzuki, T.; Shirouzu, M.; Sekine, S.-i.

10.1101/2024.03.19.585385 — biochemistry — Posted on 2024-03-21

1635 Neurogranin Modulates the Rate of Association between Calmodulin and Target Peptides

Putkey, J. A.; Hoffman, L.; Berka, V.; Wang, X.

10.1101/2024.03.21.586151 — biochemistry — Posted on 2024-03-21

1636 Fast clustering and cell-type annotation of scATAC data using pre-trained embeddings

LeRoy, N. J.; Smith, J. P.; Zheng, G.; Rymuza, J.; Gharavi, E.; Brown, D. E.; Zhang, A.; Sheffield, N. C.

10.1101/2023.08.01.551452 — genomics — Posted on 2024-03-21

1637 Perturbation-aware predictive modeling of RNA splicing using bidirectional transformers

McNally, C. P.; Abdulhay, N. J.; Khalaj, M.; Saberi, A.; Zaro, B. W.; Goodarzi, H.; Ramani, V.

10.1101/2024.03.20.585793 — genomics — Posted on 2024-03-21

1638 Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis

Bandyadka, S.; Lebo, D. P.; Mondragon, A.; Serizier, S. B.; Kwan, J.; Peterson, J. S.; Chasse, A. Y.; Jenkins, V.; Calikyan, A.; Ortega, A.; Campbell, J. D.; Emili, A.; McCall, K.

10.1101/2024.03.12.584558 — genetics — Posted on 2024-03-21

1639 Impact of Essential Genes on the Success of Genome Editing Experiments Generating 3,313 New Genetically Engineered Mouse Lines

Elrick, H.; Peterson, K. A.; Willis, B. J.; Lanza, D. G.; Acar, E. F.; Ryder, E. J.; Teboul, L.; Kasparek, P.; Birling, M.-C.; Adams, D. J.; Bradley, A.; Braun, R. E.; Brown, S. D.; Caulder, A.; Codner, G. F.; DeMayo, F. J.; Dickinson, M. E.; Doe, B.; Duddy, G.; Gertsenstein, M.; Goodwin, L. O.; Herault, Y.; Lintott, L. G.; Lloyd, K. C. K.; Lorenzo, I.; Mackenzie, M.; Mallon, A.-M.; McKerlie, C.; Parkinson, H.; Ramirez-Solis, R.; Seavitt, J. R.; Sedlacek, R.; Skarnes, W. C.; Wells, S.; Smedley, D.; White, J. K.; Wood, J. A.; International Mouse Phenotyping Consortium, ; Murray, S. A.; Heaney,

10.1101/2021.10.06.463037 — genetics — Posted on 2024-03-21

1640 Using human genetics to develop strategies to increase erythropoietic output from genome-edited hematopoietic stem and progenitor cells

Luna, S. E.; Camarena, J.; Hampton, J. P.; Majeti, K. R.; Charlesworth, C. T.; Soupene, E.; Jia, K.; Sheehan, V. A.; Cromer, M. K.; Porteus, M. H.

10.1101/2023.08.04.552064 — genetics — Posted on 2024-03-21

1641 Archaeogenetic analysis revealed East Eurasian paternal origin to the Aba royal family of Hungary

Varga, G. I. B.; Maroti, Z.; Schutz, O.; Maar, K.; Nyerki, E.; Tihanyi, B.; Varadi, O.; Ginguta, A.; Kovacs, B.; Kiss, P.; Dosztig, M.; Gallina, Z.; Torok, T.; B. Szabo, J.; Makoldi, M.; Neparaczki, E.

10.1101/2024.03.20.585718 — genetics — Posted on 2024-03-21

1642 Long-term dynamics of adaptation to a warming environment is dependent on historical background

Antunes, M. A.; Grandela, A.; Matos, M.; Simoes, P.

10.1101/2024.02.15.580572 — evolutionary biology — Posted on 2024-03-21

1643 MixtureFinder: Estimating DNA mixture models for phylogenetic analyses

Ren, H.; Wong, T. K. F.; Minh, B. Q.; Lanfear, R.

10.1101/2024.03.20.586035 — evolutionary biology — Posted on 2024-03-21

1644 Long non-coding RNAs direct the SWI/SNF complex to cell-specific enhancers

Oo, J. A.; Warwick, T.; Palfi, K.; McNicoll, F.; Cao, C.; Prieto-Garcia, C.; Zhou, Y.; Gavrilov, A. A.; Razin, S. V.; Lam, F.; Günther, S.; Cabrera-Orefice, A.; Wittig, I.; Pullamsetti, S. S.; Kurian, L.; Gilsbach, R.; Schulz, M.; Dikic, I.; Müller-McNicoll, M.; Brandes, R. P.; Leisegang, M. S.

10.1101/2024.03.21.585172 — molecular biology — Posted on 2024-03-21

1645 Inhibition of eukaryotic translation initiation factor 1A (eIF1A) and 3B (eIF3B) diminishes the psoriatic phenotype in two mouse models and human 3D model samples

Golob-Schwarzl, N.; Pilic, J.; Vrebo, A.; Bordag, N.; Shirsath, N.; Mueller, C. T.; El-Heliebi, A.; Wolf, P.

10.1101/2024.03.21.586074 — molecular biology — Posted on 2024-03-21

1646 Base composition at the start of the coding sequence controls the balance between translation initiation and mRNA degradation in E. coli .

Liponska, A.; Monlezun, L.; Wilkins, I.; Ngo, S.; Oïffer, T.; Bouchachi, C.; Hunt, J. F.; Aalberts, D. P.; Boël, G.

10.1101/2024.03.21.586065 — microbiology — Posted on 2024-03-21

1647 Development and Validation of Genome-Informed and Multigene-based qPCR and LAMP Assays for Accurate Detection of Dickeya solani: A Critical Quarantine Pathogen Threatening Potato Industry

Dobhal, S.; Santillana, G.; Stulberg, M. J.; Arizala, D.; Alvarez, A. M.; Arif, M.

10.1101/2024.03.21.586178 — microbiology — Posted on 2024-03-21

1648 The branched receptor binding complex of Ackermannviridae phages promotes adaptative host recognition

Sorensen, A. N.; Woudstra, C.; Kalmar, D.; Poppeliers, J.; Lavigne, R.; Sorensen, M. C. H.; Brondsted, L.

10.1101/2024.03.21.586117 — microbiology — Posted on 2024-03-21

1649 Stable, multigenerational transmission of the bean seed microbiome despite abiotic stress

Sulesky-Grieb, A.; Simonin, M.; Bintarti, A. F.; Marolleau, B.; Barret, M.; Shade, A.

10.1101/2024.03.21.586100 — microbiology — Posted on 2024-03-21

1650 The minimal SUF system can substitute for the canonical iron-sulfur cluster biosynthesis systems by using inorganic sulfide as the sulfur source.

Murata, M.; Murakami, T.; Yuda, E.; Mukai, N.; Zheng, X.; Kurachi, N.; Mori, S.; Ogawa, S.; Kunichika, K.; Fujishiro, T.; Wada, K.; Takahashi, Y.

10.1101/2024.03.20.586028 — microbiology — Posted on 2024-03-21

1651 Functional Redundancy in Candida auris Cell Surface Adhesins Crucial for Cell-Cell Interaction and Aggregation

Wang, T.; Sofras, D.; Montelongo-Jauregui, D.; Paiva, T.; Carolus, H.; Dufrene, Y.; Alfaifi, A.; McCracken, C.; Bruno, V.; Van Dijck, P.; Jabra-Rizk, M. A.

10.1101/2024.03.21.586120 — microbiology — Posted on 2024-03-21

1652 Identification and functional analysis of recent IS transposition events in rhizobia

Mogro, E. G.; Drahi, W. O.; Lagares, A.; Lozano, M. J.

10.1101/2024.03.21.586147 — microbiology — Posted on 2024-03-21

1653 SARS-CoV-2 infection activates inflammatory macrophages in vascular immune organoids

Chau, C. W.; To, A.; Au-Yeung, R. K. H.; Tang, K.; Xiang, Y.; Ruan, D.; Zhang, L.; Wong, H.; Zhang, S.; Au, M. T.; Chung, S.; Song, E.; Choi, D.-H.; Liu, P.; Yuan, S.; Wen, C.; Sugimura, R.

10.1101/2024.03.20.585837 — immunology — Posted on 2024-03-21

1654 Microbial cancer immunotherapy reprograms hematopoietic stem cells to enhance anti-tumor immunity

Daman, A. W.; Antonelli, A. C.; Redelman-Sidi, G.; Paddock, L.; Cheong, J. G.; Jurado, L. F.; Benjamin, A.; Jiang, S.; Ahimovic, D.; Khayat, S.; Bale, M. J.; Loutochin, O.; McPherson, V. A.; Pe'er, D.; Divangahi, M.; Pietzak, E.; Josefowicz, S. Z.; Glickman, M.

10.1101/2024.03.21.586166 — immunology — Posted on 2024-03-21

1655 APIR: Aggregating Universal Proteomics Database Search Algorithms for Peptide Identification with FDR Control

Chen, Y. E.; Ge, X.; Woyshner, K.; McDermott, M.; Manousopoulou, A.; Ficarro, S.; Marto, J.; Li, K.; Wang, L. D.; Li, J. J.

10.1101/2021.09.08.459494 — bioinformatics — Posted on 2024-03-21

1656 CELL-E: Biological zero-shot text-to-image synthesis for protein localization prediction

Khwaja, E.; Song, Y. S.; Huang, B.

10.1101/2022.05.27.493774 — bioinformatics — Posted on 2024-03-21

1657 Deep learning of antibody epitopes using molecular permutation vectors

Vardaxis, I.; Simovski, B.; Anzar, I.; Stratford, R.; Clancy, T.

10.1101/2024.03.20.585661 — bioinformatics — Posted on 2024-03-21

1658 Automated In Vitro Wound Healing Assay

Cwycyshyn, J.; Stansbury, C.; Meixner, W.; Hoying, J. B.; Muir, L. A.; Rajapakse, I.

10.1101/2023.12.23.573213 — bioengineering — Posted on 2024-03-21

1659 A multiscale model of immune surveillance in micrometastases: towards cancer patient digital twins

L. Rocha, H.; Aguilar, B.; Getz, M.; Shmulevich, I.; Macklin, P.

10.1101/2023.10.17.562733 — systems biology — Posted on 2024-03-21

1660 A regulatory B cell subpopulation expressing CD301b lectin promotes breast cancer growth

Paschall, A. V.; Nawaz, Z.; Avci, F.

10.1101/2024.03.13.584829 — immunology — Posted on 2024-03-21

1661 Reorganization of structural connectivity in the brain supports preservation of cognitive ability in healthy aging

Neudorf, J.; Shen, K.; McIntosh, A. R.

10.1101/2023.10.25.564045 — neuroscience — Posted on 2024-03-21

1662 Forskolin reverses the O-GlcNAcylation dependent decrease in GABAAR current amplitude at hippocampal synapses possibly through a neurosteroid site on GABAARs.

Phillips, S.; Chatham, J. C.; McMahon, L.

10.1101/2024.03.06.583612 — neuroscience — Posted on 2024-03-21

1663 Temporal dissociation between local and global functional adaptations of the maternal brain to childbirth: A longitudinal assessment

Lotter, L. D.; Nehls, S.; Losse, E.; Dukart, J.; Chechko, N.

10.1101/2023.08.15.553345 — neuroscience — Posted on 2024-03-21

1664 Human EEG and artificial neural networks reveal disentangled representations of object real-world size in natural images

Lu, Z.; Golomb, J. D.

10.1101/2023.08.19.553999 — neuroscience — Posted on 2024-03-21

1665 Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder Subjects

Krolewski, D. M.; Waselus, M.; Bunney, B. G.; Myers, R. M.; Barchas, J. D.; Lee, F. S.; Schatzberg, A. F.; Bunney, W. E.; Akil, H.; Watson, S. J.

10.1101/2024.03.20.585908 — neuroscience — Posted on 2024-03-21

1666 Simulation-Driven Design of Stabilized SARS-CoV-2 Spike S2 Immunogens

Nuqui, X.; Casalino, L.; Zhou, L.; Shehata, M.; Wang, A.; Tse, A. L.; Ojha, A.; Kearns, F. L.; Rosenfeld, M. A.; Miller, E. H.; Acreman, C. M.; Ahn, S.-H.; Chandran, K.; McLellan, J. S.; Amaro, R. E.

10.1101/2023.10.24.563841 — biophysics — Posted on 2024-03-21

1667 Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate

Valentino, I. M.; Llivicota-Guaman, J. G.; Dao, T. P.; Mulvey, E. O.; Lehman, A. M.; Galagedera, S. K. K.; Mallon, E. L.; Castaneda, C. A.; Kraut, D. A.

10.1101/2024.03.15.585243 — biochemistry — Posted on 2024-03-21

1668 MU-BRAIN: MUltiethnic Brain Rna-seq for Alzheimer INitiative

Yang, Z.; Cieza, B.; Reyes-Dumeyer, D.; Lee, A.; Ma, Y.; Yilmaz, E.; Lantigua, R.; Miller, G.; Brown, L.; Honig, L.; Ciener, B.; Leskinen, S.; Sivakumar, S.; Vardarajan, B.; Dugger, B.; Jin, L.-W.; Murray, M.; Dickson, D.; Rissman, R.; Hiniker, A.; Pericak-Vance, M.; Vance, J.; Foroud, T.; Kizil, C.; Teich, A.; Mayeux, R.; Tosto, G.

10.1101/2024.02.20.581250 — genetics — Posted on 2024-03-21

1669 Transcriptional responses of brain endothelium to Plasmodium falciparum patient-derived isolates in vitro

Askonas, C. F.; Storm, J.; Camarda, G.; Craig, A.; Pain, A.

10.1101/2024.01.11.575088 — cell biology — Posted on 2024-03-21

1670 Single-cell profiling reveals the intratumor heterogeneity and immunosuppressive microenvironment in cervical adenocarcinoma

Peng, Y.; Li, Y.; Ao, J.; Shen, J.; He, X.; Tang, D.; Chu, C.; Liu, C.; Weng, L.

10.1101/2024.03.20.586024 — cancer biology — Posted on 2024-03-21

1671 Ether lipids influence cancer cell fate by modulating iron uptake

Henry, W. S.; Müller, S.; Yang, J.-S.; Innes-Gold, S.; Das, S.; Reinhardt, F.; Sigmund, K.; Phadnis, V. V.; Wan, Z.; Eaton, E.; Sampaio, J. L.; Bell, G. W.; Viravalli, A.; Hammond, P. T.; Kamm, R. D.; Cohen, A. E.; Boehnke, N.; Hsu, V. W.; Levental, K. E.; Rodriguez, R.; Weinberg, R. A.

10.1101/2024.03.20.585922 — cancer biology — Posted on 2024-03-21

1672 How clinically relevant are prostate cancer cell lines? A comprehensive characterisation and multiomics comparison.

Ahmed, Z.; Mosabbir, W.; Tandon, D.; Pereira, S. P.; Cheema, U.; Loizidou, M.; Withington, J.; Moore, C.; Okoli, U.; Heavey, S.

10.1101/2024.03.20.585982 — cancer biology — Posted on 2024-03-21

1673 UDP-6-glucose dehydrogenase in hormonally responsive breast cancers

Price, M. J.; Nguyen, A. D.; Haines, C.; Baeta, C. D.; Byemerwa, J.; Mukherjee, D.; Artham, S.; Kumar, V.; Lavau, C.; Wardell, S.; Varghese, S.; Goodwin, C. R.

10.1101/2024.03.20.585919 — cancer biology — Posted on 2024-03-21

1674 BET inhibition induces GDH1-dependent glutamine metabolic remodeling and vulnerability in liver cancer

Mi, W.; You, J.; Li, L.; Zhu, L.; Xia, X.; Yang, L.; Li, F.; Xu, Y.; Bi, J.; Liu, P.; Chen, L.; Li, F.

10.1101/2024.03.20.585859 — cancer biology — Posted on 2024-03-21

1675 Targeting Diffuse Midline Glioma with a novel anti-CD99 Antibody

Balakrishnan, I.; Madhavan, K.; Pierce, A. M.; Michlin, J. A.; Brunt, B.; Chetty, S. L.; Wang, D.; DeSisto, J.; Nuss, Z.; Davidson, N.; Donson, A.; Jones, K.; Mitra, S. S.; Green, A.; Dahl, N.; Vibhakar, R.; Venkataraman, S.

10.1101/2024.03.19.585814 — cancer biology — Posted on 2024-03-21

1676 Consequences of platelet-educated cancer cells on the expression of inflammatory and metastatic glycoproteins.

Langiu, M.; Crescence, L.; Mege, D.; Dubois, C.; Panicot-Dubois, L.

10.1101/2024.03.20.585903 — cancer biology — Posted on 2024-03-21

1677 CDK12 Loss Promotes Prostate Cancer Development While Exposing Vulnerabilities to Paralog-Based Synthetic Lethality

Tien, J. C.-Y.; Chang, Y.; Zhang, Y.; Chou, J.; Cheng, Y.; Wang, X.; Yang, J.; Mannan, R.; Shah, P.; Wang, X.-M.; Todd, A. J.; Eyunni, S.; Cheng, C.; Rebernick, R. J.; Xiao, L.; Bao, Y.; Neiswender, J.; Brough, R.; Pettitt, S. J.; Cao, X.; Miner, S. J.; Zhou, L.; Wu, Y.-M.; Labanca, E.; Wang, Y.; Parolia, A.; Cieslik, M.; Robinson, D. R.; Wang, Z.; Feng, F. Y.; Lord, C. J.; Ding, K.; Chinnaiyan, A. M.

10.1101/2024.03.20.585990 — cancer biology — Posted on 2024-03-21

1678 Illuminating the Dark Cancer Phosphoproteome Through a Machine-Learned Co-Regulation Map of 26,280 Phosphosites

Jiang, W.; Jaehnig, E. J.; Liao, Y.; Yaron-Barir, T. M.; Johnson, J. L.; Cantley, L. C.; Zhang, B.

10.1101/2024.03.19.585786 — cancer biology — Posted on 2024-03-21

1679 Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers

Wang, J.; Suh, J. M.; Woo, B. J.; Navickas, A.; Garcia, K.; Yin, K.; Fish, L.; Cavazos, T.; Hanisch, B.; Markett, D.; Yu, S.; Hirst, G.; Brown-Swigart, L.; Esserman, L. J.; van 't Veer, L. J.; Goodarzi, H.

10.1101/2024.03.19.585748 — cancer biology — Posted on 2024-03-21

1680 Deep indel mutagenesis reveals the impact of amino acid insertions and deletions on protein stability and function

Topolska, M.; Beltran, T.; Lehner, B.

10.1101/2023.10.06.561180 — genomics — Posted on 2024-03-21

1681 Neurovascular Mechanisms of Cognitive Aging: Sex-Related Differences in the Average Progression of Arteriosclerosis, White Matter Atrophy, and Cognitive Decline

Bowie, D. C.; Low, K. A.; Rubenstein, S. L.; Islam, S. S.; Zimmerman, B.; Camacho, P. B.; Sutton, B. P.; Gratton, G.; Fabiani, M.

10.1101/2023.09.06.556562 — neuroscience — Posted on 2024-03-21

1682 srahunter: A User-Friendly Tool for Efficient Retrieval and Management of SRA Data

Bortoletto, E.; Frizzo, R.; Rosani, U.; Venier, P.

10.1101/2024.03.19.585745 — bioinformatics — Posted on 2024-03-21

1683 CC-Tempo: A cell-cell communication aware temporal model of cellular dynamics

Jony, S. S. R.; Rahman, M. S.; Samee, M. A. H.

10.1101/2023.12.04.569835 — bioinformatics — Posted on 2024-03-21

1684 Fast and accurate imputation of genotypes from noisy low-coverage sequencing data in bi-parental populations

Triay, C.; Boizet, A.; Fragoso, C.; Gkanogiannis, A.; Rami, J.-F.; Lorieux, M.

10.1101/2024.03.13.584787 — bioinformatics — Posted on 2024-03-21

1685 Investigating demic versus cultural diffusion and sex bias in the spread of Austronesian languages in Vietnam

Huong Thao, D.; Tran, H. D.; Mitsunaga, S.; Duc Duy, L.; Thanh Phuong, N.; Phuong Anh, N.; Tho Anh, N.; Minh Duc, B.; Thi Thu Hue, H.; Hai Ha, N.; Dang Ton, N.; Hubner, A.; Pakendorf, B.; Stoneking, M.; Inoue, I.; Thuy Duong, N.; Van Hai, N.

10.1101/2024.03.19.585662 — genomics — Posted on 2024-03-21

1686 Mapping single-cell developmental potential in health and disease with interpretable deep learning

Kang, M.; Armenteros, J. J. A.; Gulati, G. S.; Gleyzer, R.; Avagyan, S.; Brown, E. L.; Zhang, W.; Usmani, A.; Earland, N.; Wu, Z.; Zou, J.; Fields, R. C.; Chen, D. Y.; Chaudhuri, A. A.; Newman, A. M.

10.1101/2024.03.19.585637 — genomics — Posted on 2024-03-21

1687 Differential seasonal effects of ephemeral legumes in response to moisture-nitrogen coupling in the deserts of northwestern China

Xiao, Y.; Song, B.; Li, J.; Galip, N.; Yang, A.; Zhang, X.; Zhuang, W.

10.1101/2024.03.19.585727 — ecology — Posted on 2024-03-21

1688 Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium.

Grommisch, D.; Wang, M.; Eenjes, E.; Svetlicic, M.; Deng, Q.; Giselsson, P.; Genander, M.

10.1101/2024.01.11.575258 — cell biology — Posted on 2024-03-21

1689 A fatal case of peritonitis caused by Dysgonomonas capnocytophagoides harboring the novel metallo-beta-lactamase gene blaDYB-1

Imai, K.; Kodana, M.; Omachi, R.; Inoue, T.; Okada, H.; Maeda, T.

10.1101/2024.03.18.585585 — microbiology — Posted on 2024-03-21

1690 Identifying EEG Biomarkers of Depression with Novel Explainable Deep Learning Architectures

Ellis, C. A.; Lapera Sancho, M.; Miller, R. L.; Calhoun, V. D.

10.1101/2024.03.19.585728 — neuroscience — Posted on 2024-03-21

1691 Hippocampal-parietal cortex causal directed connectivity during human episodic memory formation: Replication across three experiments

Das, A.; Menon, V.

10.1101/2023.11.07.566056 — neuroscience — Posted on 2024-03-21

1692 Epigenetic and transcriptional consequences of chemically induced transposon mobilization in the endosperm

del Toro-de Leon, G.; van Boven, J.; Santos-Gonzalez, J.; Jiao, W.-B.; Schneeberger, K.; Köhler, C.

10.1101/2024.03.19.585643 — plant biology — Posted on 2024-03-21

1693 Effect of C-to-T transition at CpG sites on tumor suppressor genes in tumor development in cattle evaluated by somatic mutation analysis in enzootic bovine leukosis

Nishimori, A.; Andoh, K.; Matsuura, Y.; Okagawa, T.; Konnai, S.

10.1101/2024.03.19.585713 — cancer biology — Posted on 2024-03-21

1694 Atomistic Characterization of Beta-2-Glycoprotein I Domain V Interaction with Anionic Membranes

Hasdemir, H. S.; Pozzi, N.; Tajkhorshid, E.

10.1101/2024.03.19.585743 — biophysics — Posted on 2024-03-21

1695 AlphaFold-Multimer struggles in predicting PROTAC-mediated protein-protein interfaces

Pereira, G. P.; Gouzien, C.; Souza, P. C. T. d.; Martin, J.

10.1101/2024.03.19.585735 — bioinformatics — Posted on 2024-03-21

1696 Batch correction methods used in single cell RNA-sequencing analyses are often poorly calibrated

Antonsson, S. E.; Melsted, P.

10.1101/2024.03.19.585562 — bioinformatics — Posted on 2024-03-21

1697 Interpretable Spatial Gradient Analysis for Spatial Transcriptomics Data

Liang, Q.; Solis Soto, L.; Haymaker, C.; Chen, K.

10.1101/2024.03.19.585725 — bioinformatics — Posted on 2024-03-21

1698 Defining phylogenetic relationships: a complete and minimal set of combinatorial properties for triplets

Rineau, V.; Prin, S.

10.1101/2024.03.19.585714 — evolutionary biology — Posted on 2024-03-21

1699 Asian Mus musculus: Subspecies Divergence, Genetic Diversity, and Historical Biogeography

Amir Afzali, Y.

10.1101/2024.03.19.585722 — evolutionary biology — Posted on 2024-03-21

1700 Simulating animal movement trajectories from temporally dynamic step selection functions

Forrest, S. W.; Pagendam, D.; Bode, M.; Drovandi, C.; Potts, J. R.; Perry, J.; Vanderduys, E.; Hoskins, A. J.

10.1101/2024.03.19.585696 — ecology — Posted on 2024-03-21

1701 Tree growth is better explained by absorptive fine roots than transport fine roots

Sanaei, A.; van der Plas, F.; Chen, H.; Davids, S.; Eckhardt, S.; Hennecke, J.; Kahl, A.; Moller, Y.; Richter, R.; Schutze, J.; Wirth, C.; Weigelt, A.

10.1101/2024.03.19.585673 — ecology — Posted on 2024-03-21

1702 Biodiversity impact of the consumption of peat and wood-fired district heating

Vainio, V.; El Geneidy, S.; Halme, P.; Peura, M.; Kotiaho, J. S.

10.1101/2024.03.19.585717 — ecology — Posted on 2024-03-21

1703 Multi-decadal warming alters predator's effect on prey community composition

Niu, J.; Huss, M.; Garnier, A.; Vasemägi, A.; Gardmark, A.

10.1101/2024.03.19.585501 — ecology — Posted on 2024-03-21

1704 The autophagy protein, ATG14 safeguards against unscheduled pyroptosis activation to enable embryo transport during early pregnancy

POPLI, P.; Oestreich, A. K.; MAURYA, V. K.; ROWEN, M. N.; Masand, R.; Holtzman, M.; Zhang, Y.; P Lydon, J.; Shizuo Akira, P.; Moley, K.; Kommagnani, R.

10.1101/2024.03.19.585812 — developmental biology — Posted on 2024-03-21

1705 Integrin inactivation slows down neutrophils congesting the pre-metastatic lung in a model of breast cancer

Fercoq, F.; Cairns, G. S.; De Donatis, M.; Mackey, J. B.; Floerchinger, A.; McFarlane, A. J.; Raffo-Iraolagoitia, X. L.; Whyte, D.; Arnott, L. W.; Nixon, C.; Wiesheu, R.; Brown, L.; Al-Khalidi, S.; Norman, J. C.; Roberts, E. W.; Blyth, K.; Coffelt, S. B.; Carlin, L. M.

10.1101/2024.03.19.585724 — immunology — Posted on 2024-03-21

1706 Automating Academic Document Analysis with ChatGPT: A Mendeley Case

Abuella, M.

10.1101/2024.03.18.585620 — scientific communication and education — Posted on 2024-03-21

1707 Exploring the role of cultivar, year and plot age in the incidence of grapevine trunk diseases: insights from 20 years of regional surveys in France

Etienne, L.; Fabre, F.; Martinetti, D.; Frank, E.; Michel, L.; Bonnardot, V.; Guerin Dubrana, L.; Delmas, C. E. L.

10.1101/2024.03.19.585220 — plant biology — Posted on 2024-03-21

1708 Corticosterone release in very young siblicidal seabird chicks (Rissa tridactyla) is sensitive to environmental variability and responds rapidly and robustly to external challenges

Benowitz-Fredericks, Z. M.; Will, A. P.; Pete, S. N.; Whelan, S.; Kitaysky, A. S.

10.1101/2024.02.25.581949 — physiology — Posted on 2024-03-21

1709 Cancer-Associated Hypercalcemia Signals Through the Hindbrain to cause Anorexia

Grinman, D. Y.; Takyar, F. M.; Dann, P.; Shanabrough, M.; Brown, S.; Clemenceau, A.; Hens, J. R.; Stutz, B.; Chodosh, L. A.; Chang, W.; Schulman, G. I.; Horvath, T. L.; Wysolmerski, J. J.

10.1101/2024.03.19.585694 — cancer biology — Posted on 2024-03-21

1710 Protein Retrieval via Integrative Molecular Ensembles (PRIME) through extended similarity indices

Chen, L.; Mondal, A.; Perez, A.; Quintana, R. A. M.

10.1101/2024.03.19.585783 — biophysics — Posted on 2024-03-21

1711 Quantitative characterization of cell niches in spatial atlases

Birk, S.; Bonafonte-Pardas, I.; Feriz, A. M.; Boxall, A.; Agirre, E.; Memi, F.; Maguza, A.; Fan, R.; Castelo-Branco, G.; Theis, F. J.; Bayraktar, O.; Talavera-Lopez, C.; Lotfollahi, M.

10.1101/2024.02.21.581428 — bioinformatics — Posted on 2024-03-21

1712 Self-Supervised Learning Reveals Clinically Relevant Histomorphological Patterns for Therapeutic Strategies in Colon Cancer

Liu, B.; Polack, M.; Coudray, N.; Quiros, A. C.; Sakellaropoulos, T.; Crobach, A. S. L. P.; van Krieken, J. H. J. M.; Yuan, K.; Tollenaar, R. A. E. M.; Mesker, W. E.; Tsirigos, A.

10.1101/2024.02.26.582106 — bioinformatics — Posted on 2024-03-21

1713 Exploring Inflammatory Dysregulation in Alveolar Macrophages: Implications for Novel Therapeutic Targets in Chronic Obstructive Pulmonary Disease

Adeyanju, S.

10.1101/2024.03.20.585875 — bioinformatics — Posted on 2024-03-21

1714 Using fanyi to reduce language barriers, promote information absorption, and communication

Wang, D.; Chen, G.; Luo, X.; Zhan, L.; Xu, S.; Wang, Q.; Li, J.; Wang, R.; Wen, S.; Yu, G.

10.1101/2023.12.21.572729 — bioinformatics — Posted on 2024-03-21

1715 Persistent homology centrality improves link prediction performance in PubMed co-occurrence networks

Brown, C. A.; Wren, J. D.

10.1101/2024.03.19.585668 — bioinformatics — Posted on 2024-03-21

1716 Optimizing sequential gene expression modulation for cellular reprogramming - Coupled Boolean modeling and Reinforcement Learning based method

Singh, V.

10.1101/2024.03.19.585672 — bioinformatics — Posted on 2024-03-21

1717 Matrix fibril alignment and density modulate YAP-mediated T-cell immune suppression

Sapudom, J.; Alatoom, A.; Tipay, P.; Teo, J.

10.1101/2024.03.19.585707 — bioengineering — Posted on 2024-03-21

1718 High Resolution Outdoor Videography of Insects Using Fast Lock-On Tracking

Vo-Doan, T. T.; Titov, V. V.; Harrap, M. J.; Lochner, S.; Straw, A. D.

10.1101/2023.12.20.572558 — animal behavior and cognition — Posted on 2024-03-21

1719 CADTAD: CAncer Driver Topologically Associated Domains identify oncogenic and tumor suppressive lncRNAs

Rao, Z.; Zhang, M.; Huang, S.; Wu, C.; Zhou, Y.; Zhang, W.; Lin, X.; Zhao, D.

10.1101/2024.03.19.585685 — genomics — Posted on 2024-03-21

1720 Alanine and glutamate catabolism ensure proper sporulation by preventing premature germination and providing energy respectively

Lyu, F.; Zhang, T.; Yang, D.; Rao, L.; Liao, X.

10.1101/2024.03.04.583258 — microbiology — Posted on 2024-03-21

1721 A Generalized Framework for the Calcium Control Hypothesis Describes Weight-Dependent Synaptic Plasticity

Moldwin, T.; Azran, L. S.; Segev, I.

10.1101/2023.07.13.548837 — neuroscience — Posted on 2024-03-21

1722 The vestibulospinal nucleus is a locus of balance development

Hamling, K. R.; Harmon, K.; Kimura, Y.; Higashijima, S.-i.; Schoppik, D.

10.1101/2023.12.06.570482 — neuroscience — Posted on 2024-03-21

1723 Deep indel mutagenesis reveals the impact of amino acid insertions and deletions on protein stability and function

Topolska, M.; Beltran, T.; Lehner, B.

10.1101/2023.10.06.561180 — genomics — Posted on 2024-03-21

1724 Positive Transfer of the Whisper Speech Transformer to Human and Animal Voice Activity Detection

Gu, N.; Lee, K.; Basha, M.; Ram, S. K.; You, G.; Hahnloser, R.

10.1101/2023.09.30.560270 — animal behavior and cognition — Posted on 2024-03-21

1725 Circadian regulation of Homologous Recombination by Cryptochrome1-mediated dampening of DNA end resection

Romero-Franco, A.; Checa-Rodriguez, C.; Jimeno, S.; Castellano-Pozo, M.; Aguilera, P.; Miras, H.; Wals, A.; Jimeno-Gonzalez, S.; Lopez-Contreras, A. J.; Huertas, P.

10.1101/2023.01.22.524239 — cell biology — Posted on 2024-03-21

1726 Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells

Fleiner, A. S.; Kolnier, D.; Hagger-Vaughan, N.; Raeder, J.; Storm, J. F.

10.1101/2024.02.14.579884 — neuroscience — Posted on 2024-03-21

1727 Separate domains of the Arabidopsis ENHANCER OF PINOID drive its own polarization and recruit PIN1 to the plasma membrane

Matthes, M.; Yun, N.; Luichtl, M.; Büschges, U.; Fiesselmann, B.; Strickland, B.; Lehnardt, M.; Torres, R.

10.1101/2024.03.11.584374 — plant biology — Posted on 2024-03-21

1728 Comparative Analysis of Tickling and Conspecific Play in Tame Mice and Golden Hamsters

Dagher, S.; DeAngelo, D.; Sato, R. Y.; Norimoto, H.; Koide, T.; Ishiyama, S.

10.1101/2024.03.19.585680 — animal behavior and cognition — Posted on 2024-03-21

1729 PEACOC - Detecting and classifying a wide range of epileptiform activity patterns in rodents

Heining, K.; Kilias, A.; Janz, P.; Haas, C. A.; Egert, U.

10.1101/2024.03.14.584961 — neuroscience — Posted on 2024-03-21

1730 SaProt: Protein Language Modeling with Structure-aware Vocabulary

Su, J.; Han, C.; Zhou, Y.; Shan, J.; Zhou, X.; Yuan, F.

10.1101/2023.10.01.560349 — bioinformatics — Posted on 2024-03-21

1731 Small molecule machine learning: All models are wrong, some may not even be useful

Kretschmer, F.; Seipp, J.; Ludwig, M.; Klau, G. W.; Boecker, S.

10.1101/2023.03.27.534311 — bioinformatics — Posted on 2024-03-21

1732 Identifying associations of de novo noncoding variants with autism through integration of gene expression, sequence and sex information

Li, R.; Ernst, J.

10.1101/2024.03.20.585624 — genomics — Posted on 2024-03-21

1733 Prioritizing disease-related rare variants by integrating gene expression data

Guo, H.; Urban, A. E.; Wong, W. H.

10.1101/2024.03.19.585836 — genetics — Posted on 2024-03-21

1734 Prdm1 Positively Regulates Liver Group 1 ILCs Cancer Immune Surveillance and Preserves Functional Heterogeneity

He, J.; Gao, L.; Wang, P.; Chan, W. K.; Zheng, Y.; Zhang, Y.; Wang, J.; Chen, H.; Yang, Z.; Wang, Y.

10.1101/2023.10.20.563222 — immunology — Posted on 2024-03-21

1735 Arabidopsis uses a molecular grounding mechanism and a biophysical circuit breaker to limit floral abscission signaling

Taylor, I. W.; Patharkar, O. R.; Hsu, C.-W.; Baer, J.; Mijar, M.; Niederhuth, C. E.; Ohler, U.; Benfey, P. N.; Walker, J. C.

10.1101/2022.07.14.500021 — plant biology — Posted on 2024-03-21

1736 A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas.

Gibert, M. K.; Zhang, Y.; Saha, S.; Marcinkiewicz, P.; Dube, C.; Hudson, K.; Sun, Y.; Bednarek, S.; Chagari, B.; Sarkar, A.; Roig-Laboy, C.; Neace, N.; Saoud, K.; Setiady, I.; Hanif, F.; Schiff, D.; Kumar, P.; Kefas, B.; Hafner, M.; Abounader, R.

10.1101/2023.09.12.557444 — cancer biology — Posted on 2024-03-20

1737 MAP4 kinase-regulated reduced CLSTN1 expression in medulloblastoma is associated with increased invasiveness

Soenmez, E.; Yan, S.; Lin, M.-S.; Baumgartner, M.

10.1101/2024.03.20.585872 — cancer biology — Posted on 2024-03-21

1738 Accurately estimating pathway activity in single cells for clustering and differential analysis

Davis, D.; Wizel, A.; Drier, Y.

10.1101/2023.03.27.534310 — bioinformatics — Posted on 2024-03-20

1739 A yeast two-hybrid system to obtain triple-helical ligands from combinatorial random peptide libraries

Masuda, R.; Thant, K. P. P.; Kawahara, K.; Oki, H.; Kadonosono, T.; Kobayashi, Y.; Koide, T.

10.1101/2023.11.14.567114 — biochemistry — Posted on 2024-03-20

1740 Interpreting Cis-Regulatory Interactions from Large-Scale Deep Neural Networks for Genomics

Toneyan, S.; Koo, P. K.

10.1101/2023.07.03.547592 — genomics — Posted on 2024-03-21

1741 The genetic architecture of recombination rates is sexually-dimorphic and polygenic in wild house sparrows (Passer domesticus).

McAuley, J. B.; Servin, B.; Burnett, H. A.; Brekke, C.; Peters, L.; Hagen, I. J.; Niskanen, A. K.; Ringsby, T. H.; Husby, A.; Jensen, H.; Johnston, S. E.

10.1101/2023.01.26.525019 — genetics — Posted on 2024-03-20

1742 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

Gao, X.; Guo, W.; Liu, P.; Yuwen, M.; Liu, Z.; Tan, R.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Miao, K.; Pei, H.; Liu, L.; Zhu, C.; Wang, T.; Zhang, B.; Kang, J.

10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-21

1743 Interplay of IGF1R and estrogen signaling regulates hematopoietic stem and progenitor cells

Xie, Y.; Xiang, D.; Hu, X.; Pakula, H.; Park, E.-S.; Chi, J.; Linn, D. E.; Tao, L.; Li, Z.

10.1101/2024.03.20.585808 — cell biology — Posted on 2024-03-21

1744 Loss of an extensive ciliary connectome induces proteostasis and cell fate switching in a severe motile ciliopathy

Brody, S. L.; Pan, J.; Huang, T.; Xu, J.; Huang, H.; Koenitzer, J.; Brennan, S. K.; Nanjundappa, R.; Saba, T. G.; Berical, A.; Hawkins, F. J.; Wang, X.; Zhang, R.; Mahjoub, M. R.; Horani, A.; Dutcher, S. K.

10.1101/2024.03.20.585965 — cell biology — Posted on 2024-03-21

1745 Phage-mediated resolution of genetic conflict alters the evolutionary trajectory of Pseudomonas aeruginosa lysogens

Suttenfield, L. C.; Rapti, Z.; Steinlein, A. C.; Vera, J. C.; Kim, T.; Whitaker, R. J.

10.1101/2023.10.24.563318 — microbiology — Posted on 2024-03-20

1746 Genome-Wide Transcription Response of Staphylococcus epidermidis to Heat Shock and Medically Relevant Glucose Levels

Benjamin, K. N.; Goyal, A.; Nair, R. V.; Endy, D.

10.1101/2024.03.18.585582 — microbiology — Posted on 2024-03-20

1747 Analysis and culturing of the prototypic crAssphage reveals a phage-plasmid lifestyle

Schmidtke, D. T.; Hickey, A. S.; Liachko, I.; Sherlock, G. J.; Bhatt, A. S.

10.1101/2024.03.20.585998 — microbiology — Posted on 2024-03-21

1748 Neuropilin-1 is a co-receptor for NGF and TrkA-evoked pain

Peach, C. J.; Tonello, R.; Gomez, K.; Calderon-Rivera, A.; Bruni, R.; Bansia, H.; Maile, L.; Manu, A.-M.; Hahn, H.; Thomsen, A. R. B.; Schmidt, B. L.; Davidson, S.; des Georges, A.; Khanna, R.; Bunnett, N. W.

10.1101/2023.12.06.570398 — neuroscience — Posted on 2024-03-20

1749 Continuous Bump Attractor Networks Require Explicit Error Coding for Gain Recalibration

Secer, G.; Knierim, J. J.; Cowan, N. J.

10.1101/2024.02.12.579874 — neuroscience — Posted on 2024-03-20

1750 Cholinergic input to mouse visual cortex signals a movement state and acutely enhances layer 5 responsiveness

Yogesh, B.; Keller, G. B.

10.1101/2023.06.07.543871 — neuroscience — Posted on 2024-03-21

1751 Mcam stabilizes luminal progenitor breast cancer phenotypes via Ck2 control and Src/Akt/Stat3 attenuation

Balcioglu, O.; Gates, B. L.; Freeman, D. W.; Hagos, B. M.; Mehrabad, E. M.; Ayala-Talavera, D.; Spike, B. T.

10.1101/2023.05.10.540211 — cancer biology — Posted on 2024-03-20

1752 Emotional state dynamics impacts temporal memory

Wang, J.; Lapate, R. C.

10.1101/2023.07.25.550412 — animal behavior and cognition — Posted on 2024-03-20

1753 Using serosurveys to optimize surveillance for zoonotic pathogens

Clancey, E.; Nuismer, S. L.; Seifert, S. N.

10.1101/2024.02.22.581274 — ecology — Posted on 2024-03-20

1754 Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

Xue, Y.; Zhou, Y.; Cepko, C. L.

10.1101/2023.08.03.551766 — molecular biology — Posted on 2024-03-20

1755 Frequent intertrophic transmission of Wolbachia by parasitism but not predation

Yan, Z.-C.; Qi, L.-D.; Ji, H.-L.; Wang, X.-X.; Hong, X.-Y.; Li, Y.-X.

10.1101/2024.03.20.585917 — microbiology — Posted on 2024-03-20

1756 Functional diversification of gram-negative intermembrane phospholipid transporters by intrinsic substrate preference

Rai, A. K.; Sawasato, K.; Bennett, H. C.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M.; Mitchell, A. M.

10.1101/2023.06.21.545913 — microbiology — Posted on 2024-03-20

1757 Dynamics of Infantile Myoclonic Encephalopathy

Verma, V.

10.1101/2024.03.10.583151 — neuroscience — Posted on 2024-03-20

1758 Maternal obesity increases hypothalamic miR-505-5p expression in mouse offspring leading to altered fatty acid sensing and increased intake of high-fat food

Dearden, L.; Furigo, I. C.; Pantaleao, L. C.; de Almeida-Faria, J.; Kentistou, K. A.; Wong, L. W.-P.; Fernandez-Twinn, D. S.; Carreira, M. V.; Bidault, G.; Vidal-Puig, A.; Ong, K. K.; Perry, J. R.; Donato, J.; Ozanne, S. E.

10.1101/2022.06.01.494310 — neuroscience — Posted on 2024-03-20

1759 Sexual Dimorphism in Age-Dependent Neurodegeneration After Mild Head Trauma in Drosophila: Unveiling the Adverse Impact of Female Reproductive Signaling

Ye, C.; Ho, R.; Moberg, K.; Zheng, J. Q.

10.1101/2024.03.06.583747 — neuroscience — Posted on 2024-03-20

1760 Adolescent Thalamocortical Inhibition Alters Prefrontal Excitation-Inhibition Balance.

Petersen, D. C. K.; Raudales, R.; Kim-Silva, A.; Kellendonk, C.; Canetta, S.

10.1101/2023.11.22.568048 — neuroscience — Posted on 2024-03-20

1761 The choice-wide behavioral association study: data-driven identification of interpretable behavioral components

Kastner, D. B.; Williams, G.; Holobetz, C.; Romano, J. P.; Dayan, P.

10.1101/2024.02.26.582115 — neuroscience — Posted on 2024-03-20

1762 Nucleobindin-1 (Nucb1) disruption affects feeding, metabolism, and glucose homeostasis in mice in an age-, sex-, diet- and light cycle-dependent manner

Nasri, A.; Velez, E. J.; Rajeswari, J. J.; Hatef, A.; Unniappan, S.

10.1101/2024.03.07.584005 — physiology — Posted on 2024-03-20

1763 Effects of protein G-quadruplex interactions on phase transitions and protein aggregation

Sahoo, B.; Kocman, V.; Clark, N.; Myers, N.; Deng, X.; Wong, E. L.; Yang, H. J.; Kotar, A.; Guzman, B. B.; Dominguez, D. C.; Plavec, J.; Bardwell, J. C.

10.1101/2023.09.21.558871 — biochemistry — Posted on 2024-03-20

1764 Bioorthogonal labeling and enrichment of histone monoaminylation reveal its accumulation and regulatory function in cancer cell chromatin

Zhang, N.; Wu, J.; Hossain, F.; Peng, H.; Li, H.; Gibson, C.; Chen, M.; Zhang, H.; Gao, S.; Zheng, X.; Wang, Y.; Zhu, J.; Wang, J. J.; Maze, I.; Zheng, Q.

10.1101/2024.03.20.586010 — biochemistry — Posted on 2024-03-20

1765 High-throughput Kinetics using Capillary Electrophoresis and Robotics (HiKER) platform used to Study T7, T3, and Sp6 RNA Polymerase Misincorporation

Gardner, A. F.; Carter, Z. I.; Lund, S. R.; O'Brien, W.

10.1101/2024.03.20.585964 — biochemistry — Posted on 2024-03-20

1766 Assessment of DNA quality for whole genome library preparation

Jansson, L.; Fagerholm, S. A.; Borken, E.; Gynna, A. H.; Sidstedt, M.; Forsberg, C.; Ansell, R.; Hedman, J.; Tillmar, A.

10.1101/2024.03.20.585961 — molecular biology — Posted on 2024-03-20

1767 Co-translational sorting enables a single mRNA to generate distinct polysomes with different localizations and protein fates

Salloum, S.; Seveno, M.; El-koulali, K.; Rialle, S.; George, S.; Lemmers, B.; Zibara, K.; Eliscovich, C.; Hahne, M.; Bertrand, E.

10.1101/2024.03.20.585881 — molecular biology — Posted on 2024-03-20

1768 In-depth investigation of the mechanisms of high and low residual feed intake regulating hens during the late laying period via liver and gut microbiota.

Gao, Z.; Zheng, C.; Mao, Z.; Zheng, J.; Xu, G.; Liu, D.

10.1101/2024.03.20.585923 — microbiology — Posted on 2024-03-20

1769 Monitoring the directed evolution to a tripartite genome from a bipartite torradovirus genome

Turina, M.; Nerva, L.; Vallino, M.; Ciuffo, M.; Falk, B.; Ferriol, I.

10.1101/2024.03.20.585924 — microbiology — Posted on 2024-03-20

1770 Evidence for the key roles of the Pseudomonas syringae mobilome in shaping biotic interactions

Holtappels, D.; Rickus, G. J. E.; Morgan, T.; de Rezende, R. R.; Koskella, B.; Alfenas-Zerbini, P.

10.1101/2024.03.19.585818 — microbiology — Posted on 2024-03-20

1771 Analysis and culturing of the prototypic crAssphage reveals a phage-plasmid lifestyle

Schmidtke, D. T.; Hickey, A. S.; Liachko, I.; Sherlock, G. J.; Bhatt, A. S.

10.1101/2024.03.20.585998 — microbiology — Posted on 2024-03-20

1772 Validation of RT-qPCR primers and probes for new and old variants of SARS-CoV-2 in a world scale

Almeida, A. F. R.; Almeida, W. A.; Pereira, W. M.; Silva, R. d. S.; Venancio, L. P. R.; Fabres-Klein, M. H.; Lima, J. B.; Klein, R. C.; Araujo-Santos, T.

10.1101/2024.03.19.585194 — microbiology — Posted on 2024-03-20

1773 A T6SS in the coral pathogen Vibrio coralliilyticus secretes an arsenal of anti-eukaryotic effectors and contributes to virulence

Mass, S.; Cohen, H.; Gerlic, M.; Ushijima, B.; van Kessel, J. C.; Bosis, E.; Salomon, D.

10.1101/2024.03.20.584600 — microbiology — Posted on 2024-03-20

1774 Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission

Tiwari, A.; Myeong, J.; Hashemiaghdam, A.; Zhang, H.; Niu, X.; Laramie, M.; Stunault, M. I.; sponagel, J.; Patti, G.; Shriver, L.; Klyachko, V.; Ashrafi, G.

10.1101/2024.03.20.586011 — neuroscience — Posted on 2024-03-20

1775 Inflammasome-Inhibiting Nanoligomers are Neuroprotective Against Space-Induced Pathology in Healthy and Diseased 3D Human Motor and Pre-Frontal Cortex Brain Organoids

Sharma, S.; Gilberto, V. S.; Rask, J.; Chatterjee, A.; Nagpal, P.

10.1101/2024.03.19.585802 — neuroscience — Posted on 2024-03-20

1776 Decoding Continuous Character-based Language from Non-invasive Brain Recordings

Zhang, C.; Zheng, X.; Yin, R.; Geng, S.; Xu, J.; Gao, X.; Lv, C.; Ling, Z.; Huang, X.; Cao, M.; Feng, J.

10.1101/2024.03.19.585656 — neuroscience — Posted on 2024-03-20

1777 The effect of corticosterone on the acquisition of Pavlovian conditioned approach behavior is dependent on sex and vendor

Turfe, A.; Westbrook, S. R.; Lopez, S. A.; Chang, S. E.; Flagel, S.

10.1101/2024.03.20.586009 — neuroscience — Posted on 2024-03-20

1778 Reduced STMN2 and pathogenic TDP-43, two hallmarks of ALS, synergize to accelerate motor decline in mice

Krus, K.; Morales Benitez, A.; Strickland, A.; Milbrandt, J.; Bloom, J.; DiAntonio, A.

10.1101/2024.03.19.585052 — neuroscience — Posted on 2024-03-20

1779 Loss of prohibitin 2 in Schwann cells dysregulates key transcription factors controlling developmental myelination

Wilson, E. R.; Della-Flora Nunes, G.; Shen, S.; Moore, S.; Gawron, J.; Maxwell, J.; Syed, U.; Hurley, E.; Lanka, M.; Qu, J.; Desaubry, L.; Wrabetz, L.; Poitelon, Y.; Feltri, M. L.

10.1101/2024.03.20.585915 — neuroscience — Posted on 2024-03-20

1780 Reprogramming genetic circuits using space

Alejaldre, L.; Miro-Bueno, J.; Hueso-Gil, A.; Grozinger, L.; Tas, H.; Geibler, S.; Goni-Moreno, A.

10.1101/2024.03.20.585869 — synthetic biology — Posted on 2024-03-20

1781 Orthogonality of shell proteins across BMC subclasses in cyanobacteria

MacCready, J. S.; Dwyer, M. E.; Kerfeld, C. A.; Ducat, D. C.

10.1101/2024.03.19.585794 — synthetic biology — Posted on 2024-03-20

1782 mRNA display in cell lysates enables identification of cyclic peptides targeting the BRD3 extraterminal domain

Hurd, C. A.; Bush, J.; Powell, A. J.; Walport, L. J.

10.1101/2024.03.20.585962 — biochemistry — Posted on 2024-03-20

1783 Chemoproteomics reveals immunogenic and tumor-associated cell surface substrates of ectokinase CK2α

Delaveris, C. S.; Kong, S.; Glasgow, J.; Loudermilk, R. P.; Kirkemo, L. L.; Zhao, F.; Salangsang, F.; Phojanakong, P.; Serrano, J. A. C.; Steri, V.; Wells, J. A.

10.1101/2024.03.20.585970 — biochemistry — Posted on 2024-03-20

1784 Designing a Novel 3D Scaffold for Multiepitope Vaccine Development: Engineering Ag85a Protein for Enhanced Stability and Antigenicity

Mondal, T.; Rahman, S.; Das, A. K.; Hazra, D.; Roychowdhury, A.

10.1101/2024.03.20.585912 — biochemistry — Posted on 2024-03-20

1785 Baraitser-Winter Syndrome Hotspot Mutation R196H in Cytoskeletal β-actin Reduces F-actin Stability and Perturbs Interaction with the Arp2/3 Complex

Greve, J. N.; Manstein, D. J.

10.1101/2024.03.20.585892 — biochemistry — Posted on 2024-03-20

1786 Comparative Analysis of Tickling and Conspecific Play in Tame Mice and Golden Hamsters

Dagher, S.; DeAngelo, D.; Sato, R. Y.; Norimoto, H.; Koide, T.; Ishiyama, S.

10.1101/2024.03.19.585680 — animal behavior and cognition — Posted on 2024-03-20

1787 GWAS-informed data integration and non-coding CRISPRi screen illuminate genetic etiology of bone mineral density

Conery, M.; Pippin, J. A.; Wagley, Y.; Trang, K.; Pahl, M. C.; Villani, D. A.; Favazzo, L. J.; Ackert-Bicknell, C. L.; Zuscik, M. J.; Katsevich, E.; Wells, A. D.; Zemel, B. S.; Voight, B. F.; Hankenson, K. D.; Chesi, A.; Grant, S. F.

10.1101/2024.03.19.585778 — genomics — Posted on 2024-03-20

1788 Platelets induce cell apoptosis of cardiac cells via FasL after acute myocardial infarction

Krott, K. J.; Reusswig, F.; Dille, M. A.; Krueger, E.; Gorressen, S.; Karray, S.; Polzin, A.; Kelm, M.; Fischer, J. W.; Elvers, M.

10.1101/2024.03.20.585918 — molecular biology — Posted on 2024-03-20

1789 Towards sequential conjugation-assisted laboratory evolution (SCALE) of Cas nucleases

Swartjes, T.; Doets, K.; Staals, R. H.; van der Oost, J.

10.1101/2024.03.20.585880 — molecular biology — Posted on 2024-03-20

1790 Template Learning: Deep Learning with Domain Randomization for Particle Picking in Cryo-Electron Tomography

Harastani, M.; Patra, G.; Kervrann, C.; Eltsov, M.

10.1101/2024.03.20.585905 — molecular biology — Posted on 2024-03-20

1791 pSPObooster: a plasmid system to improve sporulation efficiency of Saccharomyces cerevisiae lab strains

Loll-Krippleber, R.; Jiang, Y. K.; Brown, G. W.

10.1101/2024.03.20.586023 — molecular biology — Posted on 2024-03-20

1792 Mono- to tetra-alkyl ether cardiolipins in a mesophilic, sulfate-reducing bacterium identified by UHPLC-HRMSn: A novel class of membrane lipids

Hopmans, E. C.; Grossi, V.; Canavesi, D. X. S.; Bale, N. J.; Cravo-Laureau, C.; Damste, J. S.

10.1101/2024.03.20.586015 — microbiology — Posted on 2024-03-20

1793 Non-peroxide antibacterial activity of Meliponula (Axestotrigona) ferruginea honey from Tanzania

Mduda, C. A.

10.1101/2024.03.20.585900 — microbiology — Posted on 2024-03-20

1794 Diversity of the O-chain biosynthetic cluster in the Pelagibacterales

Haro-Moreno, J. M.; Lopez-Perez, M.; Molina-Pardines, C.; Rodriguez-Valera, F.

10.1101/2024.03.20.585866 — microbiology — Posted on 2024-03-20

1795 Gut microbiota gate host exposure to metabolites from dietary Solanums

Liou, C. S.; Iakiviak, M.; Rajniak, J.; Murugkar, P. P.; Higginbottom, S. K.; Jasper, M.; Fischbach, M. A.; Sattely, E. S.

10.1101/2024.03.20.584512 — microbiology — Posted on 2024-03-20

1796 MOB rules: Antibiotic Exposure Reprograms Metabolism to Mobilize Bacillus subtilis in Competitive Interactions

Liu, Y.; LaBonte, S. A.; Brake, C. N.; LaFayette, C.; Rosebrock, A.; Caudy, A.; Straight, P. D.

10.1101/2024.03.20.585991 — microbiology — Posted on 2024-03-20

1797 Improved genome sequence and annotation of Cutaneotrichosporon oleaginosus ATCC 20509

Nijsse, B.; Duman-Özdamar, Z. E.; Verbokkem, J. A. C.; Butler, D.; Suarez-Diez, M.; Julsing, M. K.

10.1101/2024.03.20.585711 — microbiology — Posted on 2024-03-20

1798 Antibiotics damage the colonic mucus barrier in a microbiota-independent manner

Sawaed, J.; Zelik, L.; Levin, Y.; Feeney, R.; Naama, M.; Gordon, A.; Zigdon, M.; Rubin, E.; Telpaz, S.; Modilevsky, S.; Ben-Simon, S.; Awad, A.; Harshuk-Shabso, S.; Nuriel-Ohayon, M.; Werbner, M.; Schroeder, B. O.; Erez, A.; Bel, S.

10.1101/2024.03.19.585540 — immunology — Posted on 2024-03-20

1799 Quantitating SARS-CoV-2 Neutralizing Antibodies from Human Dried Blood Spots

Berman, K.; Van Slyke, G.; Novak, H.; Rock, J.; Bievenue, R.; Damjanovic, A.; DeRosa, K.; Mirabile, G.; Giradin, R.; Dupuis, A.; McDonough, K.; Parker, M. M.; Styer, L.; MANTIS, N. J.

10.1101/2024.03.18.585599 — immunology — Posted on 2024-03-20

1800 Autonomic Nervous System activity correlates with peak experiences induced by DMT and predicts increases in wellbeing

Bonnelle, V.; Feilding, A.; Rosas, F. E.; Nutt, D. J.; Carhart-Harris, R. L.; Timmermann, C.

10.1101/2024.03.19.585567 — neuroscience — Posted on 2024-03-20

1801 Enhanced Working Memory Representations for Rare Events

Carrasco, C. D.; Simmons, A. M.; Kiat, J. E.; Luck, S. J.

10.1101/2024.03.20.585952 — neuroscience — Posted on 2024-03-20

1802 Cell-Type Specific Reductions in Interneuron Gene Expression within Subregions of the Anterior and Posterior Cingulate Gyrus of Schizophrenia and Bipolar Disorder Subjects

Krolewski, D. M.; Waselus, M.; Bunney, B. G.; Myers, R. M.; Barchas, J. D.; Lee, F. S.; Schatzberg, A. F.; Bunney, W. E.; Akil, H.; Watson, S. J.

10.1101/2024.03.20.585908 — neuroscience — Posted on 2024-03-20

1803 Ultrasound as a reliable guide for lumbar intrathecal injection in rats: A pilot study

Pryambodho, ; Dilogo, I. H.; Tantri, A. R.; Aman, R. A.; Senapathi, T. G. A.; Purba, J. S.; Siregar, N. C.

10.1101/2024.03.20.585888 — neuroscience — Posted on 2024-03-20

1804 Effects of context changes on memory reactivation

Ozdemir, S.; Senturk, Y. D.; Unver, N.; Demircan, C.; Olivers, C. N. L.; Egner, T.; Gunseli, E.

10.1101/2024.03.20.585920 — neuroscience — Posted on 2024-03-20

1805 Comparing the effect of multi gradient echo and multi band fMRI during a semantic task

Halai, A.; Henson, R. N.; Finoia, P.; Correia, M. M.

10.1101/2024.03.20.585909 — neuroscience — Posted on 2024-03-20

1806 Convergent effects of different anesthetics are due to changes in phase alignment of cortical oscillations

Bardon, A. G.; Ballesteros, J. J.; Brincat, S. L.; Roy, J. E.; Mahnke, M. K.; Ishizawa, Y.; Brown, E. N.; Miller, E. K.

10.1101/2024.03.20.585943 — neuroscience — Posted on 2024-03-20

1807 Biphasic Internetwork Coordination is Funneled through an Electrical Synapse

Gnanabharathi, B.; Fahoum, S.-R. H.; Blitz, D. M.

10.1101/2024.03.19.585771 — neuroscience — Posted on 2024-03-20

1808 Variations in clustering of multielectrode local field potentials in the motor cortex of macaque monkeys during a reach-and-grasp task

Chambellant, F.; Falaki, A.; Moreau-Debord, I.; French, R.; Serrano, E.; Quessy, S.; Dancause, N.; Thomas, E.

10.1101/2024.03.20.585852 — neuroscience — Posted on 2024-03-20

1809 Theta transcranial alternating current stimulation is not effective in improving working memory performance

Kasanov, D.; Dorogina, O.; Mushtaq, F.; Pavlov, Y. G.

10.1101/2024.03.20.585954 — neuroscience — Posted on 2024-03-20

1810 Deciphering the Role of Aggrecan in Parvalbumin Interneurons: Unexpected Outcomes from a Conditional ACAN Knockout That Eliminates WFA+ Perineuronal Nets

Grodem, S.; Thompson, E. H.; Roe, M. B.; Vatne, G. H.; Nymoen, I.; Buccino, A.; Madland, T.; Hafting, T.; Fyhn, M.; Lensjo, K. K.

10.1101/2024.03.20.585910 — neuroscience — Posted on 2024-03-20

1811 Sub-clinical glutamate receptor antagonist combinations prevent progressive demyelination.

Mitchener, V.; Bulman, C.; Mellor, A.; Bhatt, N.; Alghamdi, B.; Nash, J.; Morgan, D.; Proctor, R.; Smith, N.; Newman, A.; Nwabiakam, V.; Stone, G.; Woznica, W.; Harper, G.; PEREZ, A. L.; PEREZ, F.; Valentino, M.; MATUTE, C.; Fern, R.

10.1101/2024.03.19.585708 — neuroscience — Posted on 2024-03-20

1812 Circadian rhythm disruption alters mammary gland morphology and accelerates cold aggressive tumorigenesis through a LILRB4-dependent pathway

Ogunlusi, O.; Sarkar, M.; Chakrabarti, A.; Boland, D.; Nguyen, T.; Sampson, J.; Nguyen, C.; Falis, D.; Jones-Hall, Y.; Fu, L.; Mallick, B.; Keene, A.; Jones, J.; Sarkar, T. R.

10.1101/2024.03.19.585534 — cancer biology — Posted on 2024-03-20

1813 Systemic coordination of whole-body tissue remodeling in sea anemone local regeneration

Cheung, S.; Bredikhin, D.; Gerber, T.; Steenbergen, P. J.; Basu, S.; Bailleul, R.; Hansen, P.; Paix, A.; Benton, M. A.; Korswagen, H. C.; Arendt, D.; Stegle, O.; Ikmi, A.

10.1101/2024.03.20.585927 — developmental biology — Posted on 2024-03-20

1814 The effect of laboratory diet and feeding on growth parameters in zebrafish

Hillman, C. S.; Cooper, A. H.; Ram, P.; Parker, M. O.

10.1101/2024.03.20.585913 — developmental biology — Posted on 2024-03-20

1815 Assistive sensory-motor perturbations influence learned neural representations

Rajeswaran, P.; Payeur, A.; Lajoie, G.; Orsborn, A. L.

10.1101/2024.03.20.585972 — neuroscience — Posted on 2024-03-20

1816 When spatial attention cannot be divided: Quadrantic enhancement of early visual processing across task-relevant and irrelevant locations

Özkan, M.; Stoermer, V. S.

10.1101/2024.03.19.585785 — neuroscience — Posted on 2024-03-20

1817 Eye-movement artifact correction in infant EEG

Srishyla, D.; Webb, S.; Elsabbagh, M.; O'Reilly, C.

10.1101/2024.03.19.585723 — neuroscience — Posted on 2024-03-20

1818 Otoferlin requires a free intravesicular C-terminal end for synaptic vesicle docking and fusion

Dulon, D.; Boutet de Monvel, J.; Plion, B.; Mallet, A.; Condamine, S.; Bouleau, Y.; Safieddine, S.

10.1101/2024.03.20.585901 — neuroscience — Posted on 2024-03-20

1819 Impact of analytic decisions on test-retest reliability of individual and group estimates in functional magnetic resonance imaging: a multiverse analysis using the monetary incentive delay task

Demidenko, M. I.; Mumford, J. A.; Poldrack, R. A.

10.1101/2024.03.19.585755 — neuroscience — Posted on 2024-03-20

1820 Parallel Encoding of Speech in Human Frontal and Temporal Lobes

Hullett, P. W.; Leonard, M. K.; Gorno-Tempini, M. L. W.; Mandelli, M. L.; Chang, E. F.

10.1101/2024.03.19.585648 — neuroscience — Posted on 2024-03-20

1821 Inverse and Postponed Impacts of Extracellular Tau PHF on Astrocytes and Neurons' Mitochondrial Function

Zufferey, V.; Parietti, E.; Barve, A.; Espourteille, J.; Varisco, Y.; Fabbri, K.; Capotosti, F.; Preitner, N.; Richetin, K.

10.1101/2024.03.19.585791 — neuroscience — Posted on 2024-03-20

1822 Gamma-TuRC proteins contribute to the dynamic organization of MTOCs during Drosophila spermatogenesis

Alzyoud, E.; Nemeth, D.; Vedelek, V.; Szögi, T.; Krecsmarik, M.; Lipinszki, Z.; Sinka, R.

10.1101/2024.03.20.585862 — cell biology — Posted on 2024-03-20

1823 BRD8 guards the pluripotent state by sensing and maintaining histone acetylation

Sun, L.; Fu, X.; Xiao, Z.; Ma, G.; Zhou, Y.; Hu, H.; Shi, L.; Li, D.; Jauch, R.; Hutchins, A.

10.1101/2024.03.20.585857 — cell biology — Posted on 2024-03-20

1824 Estrogen regulation and functional role of FGFR4 in estrogen receptor positive breast cancer

Ding, K.; Chen, L.; Levine, K. M.; Sikora, M. J.; Tasdemir, N.; Dabbs, D.; Jankowitz, R.; Hazan, R. S.; Shah, O. S.; Xavier, J. M.; LEE, A. V.; Oesterreich, S.

10.1101/2024.03.18.585626 — cancer biology — Posted on 2024-03-20

1825 Epigenetic landscape reorganization and reactivation of embryonic development genes are associated with malignancy in IDH-mutant astrocytoma

Ghisai, S. A.; van Hijfte, L.; Vallentgoed, W. R.; Tesileanu, C. M. S.; de Heer, I.; Kros, J. M.; Sanson, M.; Gorlia, T.; Wick, W.; Vogelbaum, M. A.; Brandes, A. A.; Franceschi, E.; Clement, P. M.; Nowak, A. K.; Golfinopoulos, V.; van den Bent, M. J.; French, P. J.; Hoogstrate, Y.

10.1101/2024.03.19.585212 — cancer biology — Posted on 2024-03-20

1826 Cluster-free annotation of single cells using Earth mover's distance-based classification

Forlin, R.; Tajvar, P.; Wang, N.; Dimarogonas, D.; Brodin, P.

10.1101/2024.03.18.585613 — bioinformatics — Posted on 2024-03-20

1827 SciGeneX: Enhancing transcriptional analysis through gene module detection in single-cell and spatial transcriptomics data.

Bavais, J.; Chevallier, J.; Spinelli, L.; van de Pavert, S.; Puthier, D.

10.1101/2024.03.19.585667 — bioinformatics — Posted on 2024-03-20

1828 Inhibitory Effect of Subthreshold TMS on the Long-latency Response in the Flexor Carpi Radialis

Helm, C. A.; Sergi, F.

10.1101/2024.03.18.585555 — bioengineering — Posted on 2024-03-20

1829 Structural and genetic diversity in the secreted mucins, MUC5AC and MUC5B

Plender, E. G.; Prodanov, T.; Hsieh, P.; Nizamis, E.; Harvey, W. T.; Sulovari, A.; Munson, K. M.; Kaufman, E.; O'Neal, W. K.; Valdmanis, P. N.; Marschall, T.; Eichler, E. E.

10.1101/2024.03.18.585560 — genomics — Posted on 2024-03-20

1830 Advanced median-based genetic similarity analysis in Kazakh Tazy dogs: A novel approach for breed conformity assessment

Perfilyeva, A.; Mussabayev, R.; Bespalova, K.; Kuzovleva, Y.; Bespalov, S.; Begmanova, M.; Amirgalyeva, A.; Vishnyakova, O.; Nazarenko, I.; Perfilyeva, Y.; Plakhov, K.; Djansugurova, L.

10.1101/2024.03.19.585659 — genomics — Posted on 2024-03-20

1831 A single theory for the evolution of sex chromosomes and the two rules of speciation

Lenormand, T.; Roze, D.

10.1101/2024.03.18.585601 — evolutionary biology — Posted on 2024-03-20

1832 Ibudilast Protects Retinal Bipolar Cells from Excitotoxic Retinal Damage and Activates the mTOR Pathway

Hamadmad, S.; Taylor, T. H.; Goswami, S.; Hawthorn, E.; Chaurasia, S.; Martini, D.; Summitt, D.; Zaatari, A.; Urbanski, E. G.; Bernstein, K.; Racine, J.; Satoskar, A.; El-Hodiri, H. M.; Fischer, A. J.; Cebulla, C. M.

10.1101/2024.03.18.585556 — neuroscience — Posted on 2024-03-20

1833 Development of a novel, non-invasive and whole brain biomarker of demyelination in a mouse model of multiple sclerosis

Beliard, B.; Delay, L.; Rivals, I.; Travert-Jouanneau, Y.; Ialy-Radio, N.; Le-Goazigo, A. R.; Deffieux, T.; Bradley, D. P.; Tanter, M.; Pezet, S.

10.1101/2024.03.18.585596 — neuroscience — Posted on 2024-03-20

1834 Multi-omics Identify Serotonin Transporter as a Promising Therapeutic Target for Essential Tremor

Wu, Y.; Wang, L.; Li, Y.; Lin, S.; Zhou, Z.; Zhang, S.; Xu, T.-L.; Song, X.-L.

10.1101/2024.03.18.585649 — neuroscience — Posted on 2024-03-20

1835 Ventral hippocampus mediates inter-trial responding in signaled active avoidance

Oleksiak, C. R.; Plas, S. L.; Carriaga, D. A.; Vasudevan, K.; Maren, S.; Moscarello, J. M.

10.1101/2024.03.18.585627 — neuroscience — Posted on 2024-03-20

1836 Distinct Functional Roles of Narrow and Broadband High-Gamma Activities in Human Primary Somatosensory Cortex

Ryun, S.; Chung, C. K.

10.1101/2024.03.18.585646 — neuroscience — Posted on 2024-03-20

1837 Incretin hormones and pharmacomimetics rapidly inhibit AgRP neuron activity to suppress appetite

McMorrow, H. E.; Lorch, C. M.; Hayes, N. W.; Fleps, S. W.; Frydman, J. A.; Xia, J. L.; Samms, R. J.; Beutler, L. R.

10.1101/2024.03.18.585583 — neuroscience — Posted on 2024-03-20

1838 Rapamycin Treatment Reduces Brain Pericyte Constriction in Ischemic Stroke

Beard, D.; Brown, L. S.; Morris, G. P.; Couch, Y.; Adriaanse, B. A.; Simoglou Karali, C.; Schneider, A. M.; Howells, D. W.; Redzic, Z. B.; Sutherland, B. A.; Buchan, A. M.

10.1101/2024.03.18.584333 — neuroscience — Posted on 2024-03-20

1839 Dedifferentiation of caudate-cortical connectivity is linked to reduced D1 dopamine receptor availability and poorer memory function in aging

Korkki, S. M.; Johansson, J.; Nordin, K.; Pedersen, R.; Rieckmann, A.; Salami, A.

10.1101/2024.03.18.585623 — neuroscience — Posted on 2024-03-20

1840 Evaluating the position of the uncal apex as a predictor of episodic memory across the adult lifespan

Nordin, K.; Bahrd, P.; Andersson, M.; Salami, A.

10.1101/2024.03.18.585629 — neuroscience — Posted on 2024-03-20

1841 Control of Medical Digital Twins with Artificial Neural Networks

Boetttcher, L.; Fonseca, L. L.; Laubenbacher, R.

10.1101/2024.03.18.585589 — systems biology — Posted on 2024-03-20

1842 Presence of Ecuador in the Web of Science from open access in post-pandemic period 2019-2021: A multivariate analysis.

Alvarez-munoz, P.; Pacheco-Olea, F.; Peralta Gamboa, D. A.; Aviles, A.

10.1101/2024.03.18.585617 — scientific communication and education — Posted on 2024-03-20

1843 Identifying leaf anatomy and metabolic regulators that underpin C4 photosynthesis in Alloteropsis semialata

Alenazi, A. S.; Pereira, L.; Christin, P.-A.; Osborne, C. P.; Dunning, L. T.

10.1101/2024.03.18.585502 — plant biology — Posted on 2024-03-20

1844 Molecular Phylogeny and Cryptic Morphology: A Combined Approach to Taxonomic Novelties in Polycarpaea (Caryophyllaceae) from Vietnam

Tran, T. V.; Hoang, T. T.; Le, L. B.; Le, N. T. K.; Nguyen, M. T. A.; Truong, A. T. L.; Tran, N. T.; Tran, V. T.; Le, S. V.; Duong, K. T.; Hoang, K. V. B.; Le, T. N.; Nguyen, B. V.

10.1101/2024.03.18.585622 — plant biology — Posted on 2024-03-20

1845 Manipulating plant development by editing histone methylation with the dCas9 tool: the CUC3 boundary gene as a case study

Fal, K.; Le Masson, M.; Berr, A.; CARLES, C. C.

10.1101/2024.03.18.585636 — plant biology — Posted on 2024-03-20

1846 Seaweed Amino Acid and L-Amino Acid Improve Coriander Growth

Chen, X.; Shang, Z.; Chen, H.; Wan, S.

10.1101/2024.03.18.585645 — plant biology — Posted on 2024-03-20

1847 Anion exchange regulates intestinal mucus expansion while Cftr regulates de novo mucus secretion

Ljungholm, P. L.; Ermund, A.; Garsveden, M. M. S.; Pettersson, V. L.; Gustafsson, J. K.

10.1101/2024.03.18.585614 — physiology — Posted on 2024-03-20

1848 GLP-1 receptor agonist exenatide uncouples food intake from hedonic and anticipatory regulation in non-human primates: Insights from an operant meal schedule paradigm

Knakker, B.; Inkeller, J.; Kovacs, P.; Lendvai, B.; Hernadi, I.

10.1101/2024.03.18.585513 — pharmacology and toxicology — Posted on 2024-03-20

1849 Pro-cognitive Effects of Dual Tacrine Derivatives Acting as Cholinesterase Inhibitors and NMDA Receptor Antagonists

Chvojkova, M.; Kolar, D.; Kovacova, K.; Cejkova, L.; Misiachna, A.; Hakenova, K.; Gorecki, L.; Horak, M.; Korabecny, J.; Soukup, O.; Vales, K.

10.1101/2024.03.18.585591 — pharmacology and toxicology — Posted on 2024-03-20

1850 Comparative transcriptome of normal and cancer- associated fibroblasts

Abikar, A.; Subhani, M. M. M.; Athalye, R. R.; Nadig, N.; Tamboli, N.; Babu, V.; Ramaiah, K.; Ranganathan, P.

10.1101/2024.03.18.585496 — cancer biology — Posted on 2024-03-20

1851 A molecularly engineered lectin destroys EGFR and inhibits the growth of non-small cell lung cancer

Chan, S. M.; Raglow, Z.; Pal, A.; Gitlin, S. D.; Legendre, M.; Thomas, D.; Mehta, R. K.; Tan, M.; Nyati, M. K.; Rehemtulla, A.; Markovitz, D.

10.1101/2024.03.18.585535 — cancer biology — Posted on 2024-03-20

1852 Cancer-associated DNA Hypermethylation of Polycomb Targets Requires DNMT3A Dual Recognition of Histone H2AK119 Ubiquitination and the Nucleosome Acidic Patch

Gretarsson, K. H.; Abini-Agbomson, S.; Gloor, S.; Weinberg, D. N.; McCuiston, J. L.; Kumary, V. U. N. S.; Hickman, A.; Sahu, V.; Lee, R.; Xu, X.; Lipieta, N.; Flashner, S.; Adeleke, O. A.; Popova, I. K.; Taylor, H.; Noll, K.; Windham, C. L.; Maryanski, D.; Venters, B. J.; Nakagawa, H.; Keogh, M.; Armache, K.-J.; Lu, C.

10.1101/2024.03.18.585588 — cancer biology — Posted on 2024-03-20

1853 Timing of treatment shapes the path to androgen receptor signaling inhibitor resistance in prostate cancer

Lee, E.; Zhang, Z.; Chen, C.-C.; Choi, D.; Rivera, A. C. A.; Linton, E.; Ho, Y.-j.; Love, J.; LaClair, J.; Wongvipat, J.; Sawyers, C.

10.1101/2024.03.18.585532 — cancer biology — Posted on 2024-03-20

1854 Chemotherapy induces myeloid-driven spatial T-cell exhaustion in ovarian cancer

Launonen, I.-M. P.; Erkan, E. P.; Niemiec, I.; Junquera, A.; Hincapie-Otero, M.; Afenteva, D.; Liang, Z.; Salko, M.; Szabo, A.; Perez-Villatoro, F.; Falco, M. M.; Li, Y.; Micoli, G.; Nagaraj, A.; Haltia, U.-M.; Kahelin, E.; Oikkonen, J.; Hynninen, J.; Virtanen, A.; Nirmal, A. J.; Vallius, T.; Hautaniemi, S.; Sorger, P. K.; Vaharautio, A.; Farkkila, A.

10.1101/2024.03.19.585657 — cancer biology — Posted on 2024-03-20

1855 Targeting PIKfyve-driven lipid homeostasis as a metabolic vulnerability in pancreatic cancer

Cheng, C.; Hu, J.; Mannan, R.; Bhattacharyya, R.; Rossiter, N. J.; Magnuson, B.; Wisniewski, J. P.; Zheng, Y.; Xiao, L.; Li, C.; Awad, D.; He, T.; Bao, Y.; Zhang, Y.; Cao, X.; Wang, Z.; Mehra, R.; Morlacchi, P.; Sahai, V.; Pasca di Magliano, M.; Shah, Y. M.; Ding, K.; Qiao, Y.; Lyssiotis, C. A.; Chinnaiyan, A. M.

10.1101/2024.03.18.585580 — cancer biology — Posted on 2024-03-20

1856 Multi-task deep latent spaces for cancer survival and treatment response prediction

Rintala, T. J.; Napolitano, F.; Fortino, V.

10.1101/2024.03.18.585492 — bioinformatics — Posted on 2024-03-20

1857 A Novel Tool for Multi-Omics Network Integration and Visualization: A Study of Glioma Heterogeneity

Coletti, R.; Carrilho, J.; Martins, E. P.; Goncalves, C. S.; Costa, B. M.; Lopes, M. B.

10.1101/2024.03.18.585500 — bioinformatics — Posted on 2024-03-20

1858 MaBoSS for HPC environments: Implementations of the continuous time Boolean model simulator for large CPUclusters and GPU accelerators

Smelko, A.; Kratochvil, M.; Barillot, E.; Noel, V.

10.1101/2024.03.18.585487 — bioinformatics — Posted on 2024-03-20

1859 PIPETS: A statistically robust, gene-annotation agnostic analysis method to study bacterial termination using 3'-end sequencing.

Furumo, Q.; Meyer, M. M.

10.1101/2024.03.18.585559 — bioinformatics — Posted on 2024-03-20

1860 Machine learning methods applied to classify complex diseases using genomic data

Arnal Segura, M.; Bini, G.; Krithara, A.; Paliouras, G.; Tartaglia, G. G.

10.1101/2024.03.18.585541 — bioinformatics — Posted on 2024-03-20

1861 SimMiL: Simulating Microbiome Longitudinal Data

Weaver, N. E.; Hendricks, A.

10.1101/2024.03.18.585571 — bioinformatics — Posted on 2024-03-20

1862 Permutation analysis prior to variable selection greatly enhances robustness of OPLS analysis in small cohorts

Ström, M.; Wheelock, A. M.

10.1101/2024.03.18.585475 — bioinformatics — Posted on 2024-03-20

1863 Microbial abundance estimation and metagenomic studies of holcomb creosote superfund site soil sample

D S, K.; K R, D. g.

10.1101/2024.03.19.585654 — bioinformatics — Posted on 2024-03-20

1864 Cyborg islets: implanted flexible electronics reveal principles of human islet electrical maturation

Li, Q.; Liu, R.; Lin, Z.; Zhang, X.; Silva, I. G.; Pollock, S. D.; Alvarez-Dominguez, J. R.; Liu, J.

10.1101/2024.03.18.585551 — bioengineering — Posted on 2024-03-20

1865 Connexin 43 Regulates Intercellular Mitochondrial Transfer from Human Mesenchymal Stromal Cells to Chondrocytes

Irwin, R. M.; Thomas, M. A.; Fahey, M. J.; Mayan, M. D.; Smyth, J. W.; Delco, M. L.

10.1101/2024.03.18.585552 — bioengineering — Posted on 2024-03-20

1866 A unique and biocompatible approach for corneal collagen crosslinking in vivo

GULZAR, A.; KALELI, H. N.; Koseoglu, G. D.; Hasanreisoglu, M.; Yildiz, A.; Sahin, A.; KIZILEL, S.

10.1101/2024.03.18.585574 — bioengineering — Posted on 2024-03-20

1867 Sexual dimorphism and allometry in human scapular morphology

Lee, E. C.; Lawrence, R. L.; Rainbow, M. J.

10.1101/2024.03.18.585525 — bioengineering — Posted on 2024-03-20

1868 Light-gated Integrator for Highlighting Kinase Activity in Living Cells

Lin, W.; Phatarphekar, A.; Zhong, Y.; Liu, L.; Kwon, H.-B.; Gerwick, W. H.; Wang, Y.; Mehta, S.; Zhang, J.

10.1101/2024.03.18.585554 — bioengineering — Posted on 2024-03-20

1869 Asymmetric triangular body-cover model of the vocal folds with bilateral intrinsic muscle activation

Pena, J. A. P.; Calvache, C.; Alzamendi, G. A.; Ibarra, E.; Solaque, L.; Peterson, S. D.; Zanartu, M.

10.1101/2024.03.18.585590 — bioengineering — Posted on 2024-03-20

1870 Generation of human-pig chimeric renal organoids using iPSC technology

Fujimori, K.; Yamanaka, S.; Shimada, K.; Matsui, K.; Kawagoe, S.; Kuroda, T.; Ikeda, A.; Inoue, M.; Kobayashi, E.; Yokoo, T.

10.1101/2024.03.19.584036 — bioengineering — Posted on 2024-03-20

1871 collectNET: a web server for integrated inference of cell-cell communication network

Pan, Y.; Gao, Z.; Cui, X.; Li, Z.; Jiang, R.

10.1101/2024.03.18.585493 — genomics — Posted on 2024-03-20

1872 Intricate interactions between antiviral immunity and transposable element control in Drosophila

Mayeux, C. A.; Larue, A.; Oliveira, D. S.; Varoqui, M.; Henri, H.; Rebollo, R.; Kremer, N.; Chambeyron, S.; Fablet, M.

10.1101/2024.03.18.585529 — evolutionary biology — Posted on 2024-03-20

1873 Presence of Triatoma breyeri (Reduviidae, Triatominae) in Bolivia

Lardeux, F.; Llanos, A.; Rodriguez, R.; Abate, L.; Bousses, P.; Tejerina-Lardeux, R.; Barnabe, C.; Garcia, L.

10.1101/2024.03.18.585491 — ecology — Posted on 2024-03-20

1874 Pollination services to crops of watermelon (Citrullus lanatus) and green tomato (Physalis ixocarpa) in the coastal region of Jalisco, Mexico

Delgado-Carrillo, O.; Marten-Rodriguez, S.; Ramirez-Mejia, D.; Novais, S.; Quevedo, A.; Ghilardi, A.; Sayago, R.; Lopezaraiza-Mikel, M.; Perez-Trujillo, E.; Quesada, M.

10.1101/2024.03.18.585619 — ecology — Posted on 2024-03-20

1875 Increased 'selfness' in the tumor emerges as a possible immune sculpting mechanism: A pan-cancer data analysis of 32 solid tumors in TCGA

Sakthivel, N. C.; Chinmayi, A.; Chandra, N.

10.1101/2024.03.18.585489 — immunology — Posted on 2024-03-20

1876 NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals

Mougios, N.; Cotroneo, E. R.; Imse, N.; Setzke, J.; Rizzoli, S.; Simeth, N. A.; Tsukanov, R.; Opazo, F.

10.1101/2024.03.18.585511 — neuroscience — Posted on 2024-03-20

1877 Strong heterologous electron sink outcompetes alternative electron transport pathways in photosynthesis

Hubacek, M.; Wey, L. T.; Kourist, R.; Malihan-Yap, L.; Nikkanen, L.; Allahverdiyeva, Y.

10.1101/2024.03.18.585510 — plant biology — Posted on 2024-03-20

1878 Genome assembly variation and its implications for gene discovery in nematode species

Mariene, G. M.; Wasmuth, J. D.

10.1101/2024.02.26.582167 — genomics — Posted on 2024-03-20

1879 Loss of the Na+/K+ cation pump CATP-1 suppresses nekl-associated molting defects

Fay, D. S.; Binti, S.; Edeen, P. T.

10.1101/2024.03.15.585189 — genetics — Posted on 2024-03-20

1880 Cross-transmission of resistant gastrointestinal nematodes between wildlife and transhumant sheep

Beaumelle, C.; Toigo, C.; Papet, R.; Benabed, S.; Beurier, M.; Bordes, L.; Brignone, A.; Curt-Grand-Gaudin, N.; Garel, M.; Ginot, J.; Jacquiet, P.; Miquel, C.; Poirel, M.-T.; Serafino, A.; Vannard, E.; Bourgoin, G.; Yannic, G.

10.1101/2023.07.21.550073 — ecology — Posted on 2024-03-20

1881 Glycerol degradation in the thermoacidophilic crenarchaeon Sulfolobus acidocaldarius involves an unusual glycerol-3-phosphate dehydrogenase

Schmerling, C.; Schroeder, C.; Zhou, X.; Busche, T.; Kalinowski, J.; Montero, L.; Schmitz, O.; Kaschani, F.; Ninck, S.; Kaiser, M.; Bost, J.; Wassmer, B.; Albers, S.-V.; Siebers, B.; Braesen, C.

10.1101/2024.02.29.582781 — microbiology — Posted on 2024-03-20

1882 Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation

Chatterjee, P.; Garcia, M.; Cote, J.; Yun, K.; Legerme, G.; Habib, R.; Tripepi, M.; Young, C.; Kulp, D. W.; Dyall-Smith, M.; Pohlschroder, M.

10.1101/2024.03.04.583388 — microbiology — Posted on 2024-03-20

1883 A physiologically-based digital twin for alcohol consumption - predicting real-life drinking responses and long-term plasma PEth

Podeus, H.; Simonsson, C.; Nasr, P.; Ekstedt, M.; Kechagias, S.; Lundberg, P.; Lovfors, W.; Cedersund, G.

10.1101/2023.08.18.553836 — systems biology — Posted on 2024-03-20

1884 Transcriptomics effects of per- and polyfluorinated alkyl substances in differentiated neuronal cells

Running, L.; Karageorgiou, C.; Gokcumen, O.; Aga, D.; Atilla, G. E.

10.1101/2024.01.26.577438 — pharmacology and toxicology — Posted on 2024-03-20

1885 Guiding a language-model based protein design method towards MHC Class-I immune-visibility profiles for vaccines and therapeutics

Gasser, H.-C.; Oyarzun, D.; Rajan, A.; Alfaro, J.

10.1101/2023.07.10.548300 — bioinformatics — Posted on 2024-03-20

1886 Expression dynamics of long non-coding RNAs during imaginal disc development and regeneration in Drosophila

Camilleri-Robles, C.; Amador, R.; Tiebe, M.; Teleman, A.; Serras, F.; Guigo, R.; Corominas, M.

10.1101/2024.03.19.585729 — developmental biology — Posted on 2024-03-20

1887 Perilipin membrane-integration determines Lipid Droplet heterogeneity in differentiating adipocytes

Majchrzak, M.; Stojanovic, O.; Ajjaji, D.; Ben M'barek, K.; Omrane, M.; THIAM, A. R.; Klemm, R. W.

10.1101/2023.10.30.564726 — cell biology — Posted on 2024-03-20

1888 WITHDRAWN: The cardiac lncRNA Chantico directly regulates Cxcl1 chemokine transcription

Hall, J. M.; Kainth, A. S.; Rowton, M. J.; Lu, E.; Haddad, G.; Keplinger, A. J.; Scepanovic, J.; Perez-Cervantes, C.; Chan, S. S. K.; Piccirilli, J. A.; Moskowitz, I. P.; Ruthenburg, A. J.

10.1101/2021.12.23.474040 — molecular biology — Posted on 2024-03-20

1889 VaxSeer: Selecting influenza vaccines through evolutionary and antigenicity models

Shi, W.; Wohlwend, J.; Wu, M.; Barzilay, R.

10.1101/2023.11.14.567037 — immunology — Posted on 2024-03-20

1890 Sex classification from functional brain connectivity: Generalization to multiple datasets

Wiersch, L.; Friedrich, P.; Hamdan, S.; Komeyer, V.; Hoffstaedter, F.; Patil, K. R.; Eickhoff, S. B.; Weis, S.

10.1101/2023.08.30.555495 — neuroscience — Posted on 2024-03-20

1891 Analysis of multi-condition single-cell data with latent embedding multivariate regression

Ahlmann-Eltze, C.; Huber, W.

10.1101/2023.03.06.531268 — bioinformatics — Posted on 2024-03-20

1892 Comprehensive machine learning boosts structure-based virtual screening for PARP1 inhibitors

Caba, K.; Tran-Nguyen, V.-K.; Rahman, T.; Ballester, P.

10.1101/2024.03.15.585277 — bioinformatics — Posted on 2024-03-20

1893 Unraveling the Evolutionary Trajectory of LHCI in Red-Lineage Algae: Conservation, Diversification, and Neolocalization

Kumazawa, M.; Ifuku, K.

10.1101/2024.03.16.585336 — evolutionary biology — Posted on 2024-03-20

1894 Bridging the gap between the evolutionary dynamics and the molecular mechanisms of meiosis : a model based exploration of the PRDM9 intra-genomic Red Queen

Genestier, A.; Duret, L.; Lartillot, N.

10.1101/2023.03.08.531712 — evolutionary biology — Posted on 2024-03-20

1895 SIRV: Spatial inference of RNA velocity at the single-cell resolution

Abdelaal, T.; Grossouw, L.; Pasterkamp, R. J.; Lelieveldt, B. P. F.; Reinders, M. J. T.; Mahfouz, A.

10.1101/2021.07.26.453774 — bioinformatics — Posted on 2024-03-20

1896 Epithelial cell chirality emerges through the dynamic concentric pattern of actomyosin cytoskeleton

Yamamoto, T.; Ishibashi, T.; Mimori-Kiyosue, Y.; Hiver, S.; Tokushige, N.; Tarama, M.; Takeichi, M.; Shibata, T.

10.1101/2023.08.16.553476 — cell biology — Posted on 2024-03-20

1897 Identification of a Rabenosyn-5 like protein and Rab5b in host cell cytosol uptake reveals conservation of endosomal transport in malaria parasites

Sabitzki, R.; Rossmann, A.-L.; Schmitt, M.; Flemming, S.; Guillen-Samander, A.; Behrens, H. M.; Jonscher, E.; Hoehn, K.; Froehlke, U.; Spielmann, T.

10.1101/2023.04.05.535711 — microbiology — Posted on 2024-03-20

1898 Unravelling the neural dynamics of hypnotic susceptibility: Aperiodic neural activity as a central feature of hypnosis

Landry, M.; da Silva Castanheira, J.; Boisvert, C.; Rousseaux, F.; Sackur, J.; Raz, A.; Ogez, D.; Rainville, P.; Jerbi, K.

10.1101/2023.11.16.567097 — neuroscience — Posted on 2024-03-20

1899 Deletion of FNDC5/Irisin modifies murine osteocyte function in a sex-specific manner

Shimonty, A.; Pin, F.; Prideaux, M.; Peng, G.; Huot, J.; Kim, H.; Rosen, C. j.; Spiegelman, B. M.; Bonewald, L. F.

10.1101/2023.11.06.565774 — physiology — Posted on 2024-03-20

1900 Deciphering a beetle clock: individual and sex-dependent variation in daily activity patterns

R, R.; Prueser, T.; Schulz, N. K. E.; Mayer, P. M. F.; Ogueta, M.; Stanewsky, R.; Kurtz, J.

10.1101/2024.03.18.585527 — animal behavior and cognition — Posted on 2024-03-20

1901 Calcineurin promotes adaptation to chronic stress through two distinct mechanisms

Flynn, M. J.; Harper, N. W.; Li, R.; Zhu, L. J.; Lee, M. J.; Benanti, J. A.

10.1101/2024.03.19.585797 — cell biology — Posted on 2024-03-20

1902 The intracellular Ca2+ sensitivity of transmitter release from neocortical boutons

Bornschein, G.; Brachtendorf, S.; Eshra, A.; Kraft, R.; Eilers, J.; Hallermann, S.; Schmidt, H.

10.1101/2024.02.26.582057 — neuroscience — Posted on 2024-03-20

1903 Motor cortex directly excites the output nucleus of the basal ganglia, the substantia nigra pars reticulata.

Thompson, W. S.; Grillner, S.; Silberberg, G.

10.1101/2024.03.19.585632 — neuroscience — Posted on 2024-03-20

1904 The impact of Arctic environments on human cerebral blood flow

Liu, F.; Zheng, T.; Chen, J.; Liang, H.; Li, G.; Hao, J.

10.1101/2024.03.17.585446 — physiology — Posted on 2024-03-20

1905 Evolution of phenotypic plasticity leads to tumor heterogeneity with implications for therapy

Syga, S.; Jain, H. P.; Krellner, M.; Hatzikirou, H.; Deutsch, A.

10.1101/2024.03.18.585460 — cancer biology — Posted on 2024-03-20

1906 WildPose: A Long-Range 3D wildlife motion capture system

Muramatsu, N.; Shin, S.; Deng, Q.; Markham, A.; Patel, A.

10.1101/2024.02.05.578861 — animal behavior and cognition — Posted on 2024-03-20

1907 Ground-truth validation of uni- and multivariate lesion inference approaches

Zavaglia, M.; Malherbe, C.; Schlaadt, S.; Nachev, P.; Hilgetag, C. C.

10.1101/2023.03.28.534534 — neuroscience — Posted on 2024-03-20

1908 Shedding light on blue-green photosynthesis: A wavelength-dependent mathematical model of photosynthesis in Synechocystis sp. PCC 6803

Pfennig, T.; Kullmann, E.; Zavrel, T.; Nakielski, A.; Ebenhöh, O.; Cerveny, J.; Bernat, G.; Matuszynska, A. B.

10.1101/2023.06.30.547186 — plant biology — Posted on 2024-03-20

1909 Calcium-driven In Silico Inactivation of a Human Olfactory Receptor

Pirona, L.; Ballabio, F.; Alfonso-Prieto, M.; Capelli, R.

10.1101/2024.01.31.578070 — biophysics — Posted on 2024-03-20

1910 Functional omics of ORP7 in primary endothelial cells.

Taskinen, J. H.; Holopainen, M.; Ruhanen, H.; Kakela, R.; Olkkonen, V. M.

10.1101/2024.03.19.585674 — molecular biology — Posted on 2024-03-20

1911 The bidirectional role of GABAA and GABAB receptors during the differentiation process of neural precursor cells of thesubventricular zone

Gutierrez-Castaneda, N. E.; Martinez-Rojas, V. A.; Ochoa-de la Paz, L. D.; Galvan, E. J.

10.1101/2024.03.19.585835 — neuroscience — Posted on 2024-03-20

1912 Speech and music recruit frequency-specific distributed and overlapping cortical networks

te Rietmolen, N.; Mercier, M.; Trebuchon, A.; Morillon, B.; Schon, D.

10.1101/2022.10.08.511398 — neuroscience — Posted on 2024-03-20

1913 Causal Interactions between Phase- and Amplitude-Coupling in Cortical Networks

Galindo Leon, E. E.; Nolte, G.; Pieper, F.; Engler, G.; Engel, A. K.

10.1101/2024.03.19.585825 — neuroscience — Posted on 2024-03-20

1914 Family matters: Linking population growth, kin interactions, and African elephant social groups

Croll, J. C.; Caswell, H.

10.1101/2024.03.19.585476 — ecology — Posted on 2024-03-20

1915 Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by regulating cAMP level

Khan, H.; Paul, P.; Goar, H.; Bamniya, B.; Baid, N.; Sarkar, D.

10.1101/2022.03.07.483216 — microbiology — Posted on 2024-03-20

1916 Synapse specific and plasticity-regulated AMPAR mobility tunes synaptic integration

Nowacka, A.; Getz, A. M.; Zieger, H.; Bessa-Neto, D.; Breillat, C.; Daburon, S.; Lemoigne, C.; Marais, S.; Ducros, M.; Penn, A. C.; Sainlos, M.; Choquet, D.

10.1101/2024.03.19.584837 — neuroscience — Posted on 2024-03-20

1917 deepGOLSA: Goal-directed planning with subgoal reduction models human brain activity

Cheng, H.; Brown, J.

10.1101/2024.03.19.585826 — neuroscience — Posted on 2024-03-20

1918 CDK-4 regulates nucleolar size and metabolism at the cost of late life fitness in C. elegans

Webster, R. L.; Quintana, M.; Kafri, R.; Derry, B.

10.1101/2024.01.25.577258 — cell biology — Posted on 2024-03-19

1919 Vacuolar H+-ATPase Determines Daughter Cell Fates through Asymmetric Segregation of the Nucleosome Remodeling and Deacetylase Complex

Xie, Z.; Chai, Y.; Zhu, Z.; Shen, Z.; Guo, Z.; Zhao, Z.; Xiao, L.; Du, Z.; Ou, G.; Li, W.

10.1101/2023.06.25.546476 — cell biology — Posted on 2024-03-19

1920 One gene - two proteins: The C-terminus of the prototypical M2 muscarinic receptor localizes to the mitochondria and regulates cell respiration.

Petragnano, F.; Fasciani, I.; Wang, Z.; Edwards, R.; Telugu, N.; Pietrantoni, I.; Zabel, U.; Zauber, H.; Grieben, M.; Terzenidou, M. E.; Di Gregorio, J.; Pellegrini, C.; Santini, S.; Taddei, A. R.; Poehl, B.; Aringhieri, S.; Carli, M.; Aloisi, G.; Marampon, F.; Charlesworth, E.; Roman, A.; Diecke, S.; Flati, V.; Giorgi, F.; Scarselli, M.; Tobin, A. B.; Amicarelli, F.; Tokatlidis, K.; Rossi, M.; Lohse, M. J.; Annibale, P.; Maggio, R.

10.1101/2021.04.13.438299 — cell biology — Posted on 2024-03-19

1921 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

Gao, X.; Yuwen, M.; Guo, W.; Liu, P.; Liu, Z.; Tan, R.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Liu, L.; Zhu, C.; Wang, T.; Zhang, B.; Kang, J.

10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-19

1922 Fyn-mediated phosphorylation of Menin disrupts telomere maintenance in stem cells

Paul, S.; McCourt, P. M.; Le, L. T. M.; Ryu, J.; Czaja, W.; Bode, A. M.; Contreras-Galindo, R.; Dong, Z.

10.1101/2023.10.04.560876 — molecular biology — Posted on 2024-03-19

1923 A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages

Yeh, T.-Y.; Feehley, M. C.; Feehley, P. J.; Ooi, V. Y.; Hung, Y.-Y.; Wang, S.-C.; Contreras, G. P.

10.1101/2024.03.19.585677 — microbiology — Posted on 2024-03-19

1924 High-resolution profiling of bacterial and fungal communities using pangenome-informed taxon-specific amplicons and long-read sequencing

Stalder, L.; Maurhofer, M.; Croll, D.

10.1101/2023.07.17.549274 — microbiology — Posted on 2024-03-19

1925 Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

Yulo, P. R.; Desprat, N.; Gerth, M. L.; Ritzl-Rinkenberger, B.; Farr, A. D.; Liu, Y.; Zhang, X.-X.; Miller, M.; Cava, F.; Rainey, P. B.; Hendrickson, H. L.

10.1101/263681 — microbiology — Posted on 2024-03-19

1926 Spyglass: a framework for reproducible and shareable neuroscience research

Lee, K. H.; Denovellis, E. L.; Ly, R.; Magland, J.; Soules, J.; Comrie, A. E.; Gramling, D. P.; Guidera, J. A.; Nevers, R.; Adenekan, P.; Brozdowski, C.; Bray, S. R.; Monroe, E.; Bak, J. H.; Coulter, M.; Sun, X.; Broyles, E.; Shin, D.; Chiang, S.; Holobetz, C.; Tritt, A.; Ruebel, O.; Nguyen, T.; Yatsenko, D.; Chu, J.; Kemere, C.; Garcia, S.; Buccino, A.; Frank, L. M.

10.1101/2024.01.25.577295 — neuroscience — Posted on 2024-03-19

1927 Network analysis of Marmoset cortical connections reveals pFC and sensory clusters

Pailthorpe, B. A.

10.1101/2024.03.04.582858 — neuroscience — Posted on 2024-03-19

1928 Reconstructing Voice Identity from Noninvasive Auditory Cortex Recordings

Lamothe, C.; Thoret, E.; Trapeau, R.; Giordano, B. L.; Sein, J.; Takerkart, S.; Ayache, S.; Artieres, T.; Belin, P.

10.1101/2024.02.27.582302 — neuroscience — Posted on 2024-03-19

1929 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma

Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Jing, J.; Athukuri, P.; Wang, S.; Harmanci, A. O.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.

10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-19

1930 Energy landscapes of peptide-MHC binding

Collesano, L.; Luksza, M.; Lassig, M.

10.1101/2024.03.19.585687 — biophysics — Posted on 2024-03-19

1931 Elevator-type Mechanism of the Cyanobacterial Bicarbonate Transporter

Chan, M.; Alfawaz, Y.; Paul, A.; Shukla, D.

10.1101/2022.06.08.495363 — biophysics — Posted on 2024-03-19

1932 Multi-ContrastiveVAE disentangles perturbation effects in single cell images from optical pooled screens

Wang, Z. J.; Lopez, R.; Huetter, J.-C.; Kudo, T.; Yao, H.; Hanslovsky, P.; Hoeckendorf, B.; Moran, R.; Richmond, D.; Regev, A.

10.1101/2023.11.28.569094 — bioinformatics — Posted on 2024-03-19

1933 Reference Sequence Browser: An R application with a User-Friendly GUI to rapidly query sequence databases

Rapp, S. L.; Tapias Gomez, J.; Ramesh, S.; Levine, B.; Tapias-Gomez, D.; Chung, D.; Truong, Z.

10.1101/2023.09.20.558722 — bioinformatics — Posted on 2024-03-19

1934 Semantical and Geometrical Protein Encoding Toward Enhanced Bioactivity and Thermostability

Tan, Y.; Zhou, B.; Zheng, L.; Fan, G.; Hong, L.

10.1101/2023.12.01.569522 — bioengineering — Posted on 2024-03-19

1935 Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO2

Brotherton, D. H.; Nijjar, S.; Savva, C. G.; Dale, N.; Cameron, A. D.

10.1101/2023.08.22.554292 — biochemistry — Posted on 2024-03-19

1936 Senescent cells inhibit muscle differentiation via the SASP-lipid 15d-PGJ2 mediated modification and control of HRas

Pundlik, S. S.; Barik, A.; Venkatesvaran, A.; Sahoo, S. S.; Jaysingh, M. A.; Math, R. G. H.; Ramanathan, A.

10.1101/2023.12.23.573200 — biochemistry — Posted on 2024-03-19

1937 Hidden evolutionary constraints dictate the retention of coronavirus accessory genes

Goldstein, S. A.; Feeley, T. M.; Babler, K. M.; Hilbert, Z. A.; Downhour, D. M.; Moshiri, N.; Elde, N. C.

10.1101/2023.10.12.561935 — evolutionary biology — Posted on 2024-03-19

1938 Understanding systems level metabolic adaptation resulting from osmotic stress

Tremblay, A.; Bekiaris, P. S.; Klamt, S.; Mahadevan, R.

10.1101/2024.03.19.585265 — microbiology — Posted on 2024-03-19

1939 Functional diversification of gram-negative intermembrane phospholipid transporter function by intrinsic substrate preference

Rai, A. K.; Sawasato, K.; Bennett, H. C.; Kozlova, A.; Sparagna, G. C.; Bogdanov, M.; Mitchell, A. M.

10.1101/2023.06.21.545913 — microbiology — Posted on 2024-03-19

1940 Three Prime Repair Exonuclease 1 preferentially degrades the integration-incompetent HIV-1 DNA through favorable kinetics, thermodynamic, structural and conformational properties.

Prakash, P.; Khodke, P.; Balasubramaniam, M.; Davids, B.-O.; Hollis, T.; Davis, J.; Pandhare, J.; Kumbhar, B.; Dash, C.

10.1101/2024.03.19.585766 — biochemistry — Posted on 2024-03-19

1941 Biglycan Promotes Glioma Cell Line Epithelial-Mesenchymal Transition and Temozolomide Resistance in Vitro

Han, X.; Zheng, Y.

10.1101/2024.03.19.581854 — molecular biology — Posted on 2024-03-19

1942 Functional omics of ORP7 in primary endothelial cells.

Taskinen, J. H.; Holopainen, M.; Ruhanen, H.; Kakela, R.; Olkkonen, V. M.

10.1101/2024.03.19.585674 — molecular biology — Posted on 2024-03-19

1943 Model-driven engineering of Cutaneotrichosporon oleaginosus ATCC 20509 for improved microbial oil production

Duman-Özdamar, Z. E.; Julsing, M. K.; Verbokkem, J. A. C.; Wolbert, E.; Martins dos Santos, V. A. P.; Hugenholtz, J.; Suarez-Diez, M.

10.1101/2024.03.19.585731 — molecular biology — Posted on 2024-03-19

1944 Regulation of Diseases-Associated Microglia in the Optic Nerve by Lipoxin B4 and Ocular Hypertension

Maurya, S.; Lin, M.; Karnam, S.; Singh, T.; Kumar, M.; Ward, E. L.; Flanagan, J.; Gronert, K.

10.1101/2024.03.18.585452 — molecular biology — Posted on 2024-03-19

1945 Allele Sails: launching traits and fates into wild populations with DNA sequence modifiers

Johnson, M. L.; Hay, B.; Maselko, M.

10.1101/2024.03.18.585647 — synthetic biology — Posted on 2024-03-19

1946 Enrichment of allelic editing outcomes by Prime Editing in iPS cells

Niwa, R.; Matsumoto, T.; Liu, A. Y.; Kawato, M.; Kondo, T.; Tsukita, K.; Inoue, H.; Maurissen, T. L.; Woltjen, K.

10.1101/2024.03.19.585665 — bioengineering — Posted on 2024-03-19

1947 The origin and evolution of cultivated rice and genomic signatures of heterosis for yield traits in super-hybrid rice

Liu, D.; Yin, H.; Li, T.; Wang, L.; Lu, S.; Yu, H.; Sun, X.; Zhang, T.; Zhao, Q.; ZHAO, Y.

10.1101/2024.03.19.585738 — evolutionary biology — Posted on 2024-03-19

1948 DNA methylation shows footprints of altitude selection in the clonal plant species Fragaria vesca

Le veve, A.; Sammarco, I.; Latzel, V.; Lafon-Placette, C.

10.1101/2024.03.19.585697 — evolutionary biology — Posted on 2024-03-19

1949 Towards Interpretable Cryo-EM: Disentangling Latent Spaces of Molecular Conformations

Klindt, D. A.; Hyvarinen, A.; Levy, A.; Miolane, N.; Poitevin, F.

10.1101/2024.03.18.585544 — molecular biology — Posted on 2024-03-19

1950 Comparative venom analysis between melanistic and normally-colored phenotypes of the common adder (Vipera berus)

Schulte, L.; Uhrig, L.; Eichberg, J.; Schwartze, M.; Auth, I.; Schulz, M.; Lindner, T.; Hien, P.; Hardes, K.; Vilcinskas, A.; Lueddecke, T.

10.1101/2024.03.18.585504 — molecular biology — Posted on 2024-03-19

1951 HOCl-producing Electrochemical Bandage is Active in Murine Polymicrobial Wound Infection

Fleming, D.; Bozyel, I.; Koscianski, C. A.; Ozdemir, D.; Karau, M. J.; Cuello, L.; Anoy, M. M. I.; Gelston, S.; Schuetz, A. N.; Greenwood-Quaintance, K. E.; Mandrekar, J. N.; Beyenal, H.; Patel, R.

10.1101/2024.03.19.585100 — microbiology — Posted on 2024-03-19

1952 The impact of DNA extraction on the quantification of Legionella, with implications for ecological studies

Cavallaro, A.; Gabrielli, M.; Hammes, F.; Rhoads, W. J.

10.1101/2024.03.19.585788 — microbiology — Posted on 2024-03-19

1953 Medication Use is Associated with Distinct Microbial Features in Anxiety and Depression

Dilmore, A. H.; Kuplicki, R.; McDonald, D.; Kumar, M.; Estaki, M.; Youngblut, N. D.; Tyakht, A.; Ackermann, G.; Blach, C.; MahmoudianDehkordi, S.; Dunlop, B.; Bhattacharyya, S.; Guinjoan, S.; Mandaviya, P.; Ley, R.; Kaddurah-Daouk, R.; Paulus, M. P.; Knight, R.; Alzheimer Gut Microbiome Project Consortium,

10.1101/2024.03.19.585820 — microbiology — Posted on 2024-03-19

1954 Mycobacterium dormancy and antibiotic tolerance within the retinal pigment epithelium of ocular tuberculosis

Liu, R.; Dang, J.; Rhoeun, L.; Lee, J.-J.; Ameri, H.; Rao, N.; Eoh, H.

10.1101/2024.03.18.585612 — microbiology — Posted on 2024-03-19

1955 Long read sequencing provides an insight into plasmids found among carbapenemase producing Enterobacterales from hospitals in the United Kingdom during 2021 to 2023

Turton, J. F.; Turton, J. A.

10.1101/2024.03.19.585710 — microbiology — Posted on 2024-03-19

1956 14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation

Rial, S. A.; You, Z.; Vivoli, A.; Sean, D.; Alkhoury, A.; Lavoie, G.; Civelek, M.; Martinez-sanchez, A.; Roux, P. P.; Durcan, T.; Lim, G.

10.1101/2024.03.18.585495 — physiology — Posted on 2024-03-19

1957 Molecular basis of mRNA delivery to the bacterial ribosome

Webster, M. W.; Chauvier, A.; Rahil, H.; Graziadei, A.; Charles, K.; Takacs, M.; Saint-Andre, C.; Rappsilber, J.; Walter, N. G.; Weixlbaumer, A.

10.1101/2024.03.19.585789 — biochemistry — Posted on 2024-03-19

1958 Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium

Ma, C.; Luo, Y.; Zhang, C.; Cheng, C.; Hua, N.; Liu, X.; Wu, J.; Qin, L.; Yu, P.; Luo, J.; Yang, F.; Jiang, L.-H.; Zhang, G.; Yang, W.

10.1101/2024.03.18.584035 — evolutionary biology — Posted on 2024-03-19

1959 Lossless Single-Molecule Counting To Absolute QuantifyProteoforms

10.1101/2024.03.19.585761 — molecular biology — Posted on 2024-03-19

1960 Genetic investigation of GPI anchored Bd37 orthologs in Babesia divergens group and use of recombinant protein for ecological survey in deer.

Niikura, A. Z.; Hagiwara, K.; Imaoka, K.; Morikawa, S.

10.1101/2024.03.19.585777 — microbiology — Posted on 2024-03-19

1961 A diverse gut virome from Drosophila melanogaster

Ansari, M. H.; Staubach, F.; Alacatli, N.; Obbard, D. J.

10.1101/2024.03.19.585549 — microbiology — Posted on 2024-03-19

1962 Molecular basis for the activation of the Fatty Acid Kinase complex of Staphylococcus aureus

Myers, M. J.; Xu, Z.; Ryan, B. J.; DeMars, Z. R.; Ridder, M. J.; Johnson, D. K.; Krute, C. N.; Flynn, T. S.; Kashipathy, M. M.; Battaile, K. P.; Schnicker, N. J.; Lovell, S.; Freudenthal, B. D.; Bose, J. L.

10.1101/2024.03.19.585040 — microbiology — Posted on 2024-03-19

1963 Investigating the interactions of the cucumber mosaic virus 2b protein with the viral 1a replicase component and the cellular RNA silencing factor Argonaute 1

Crawshaw, S.; Murphy, A. M.; Rowling, P. J. E.; Nietlispach, D.; Itzhaki, L. S.; Carr, J. P.

10.1101/2024.03.18.585484 — plant biology — Posted on 2024-03-19

1964 Grapevine Shiraz Disease-associated viruses lead to significant yield losses by altering transcription of genes related to defence responses and photosynthesis

Nagahatenna, D.; Onetto, C. A.; Wang, Y. M.; Borneman, A. R.; Pagay, V. V.

10.1101/2024.03.18.585633 — plant biology — Posted on 2024-03-19

1965 mLiftOver: Harmonizing Data Across Infinium DNA Methylation Platforms

Chen, B. H.; Zhou, W.

10.1101/2024.03.18.585415 — bioinformatics — Posted on 2024-03-19

1966 CRISPR-Cas9 enables efficient genome engineering of the strictly lytic, broad host-range staphylococcal bacteriophage K

Fernbach, J.; Baggenstos, J.; Riedo, J.; McCallin, S.; Loessner, M. J.; Kilcher, S.

10.1101/2024.03.19.585701 — bioengineering — Posted on 2024-03-19

1967 Precision and efficacy of RNA-guided DNA integration in high-expressing muscle loci

Padmaswari, M. H.; Bulliard, G. N.; Agrawal, S.; Jia, M. S.; Nelson, C. E.

10.1101/2024.03.18.582796 — bioengineering — Posted on 2024-03-19

1968 Stable and robust Xi and Y transcriptomes drive cell-type-specific autosomal and Xa responses in vivo and in vitro in four human cell types

Blanton, L. V.; San Roman, A. K.; Wood, G.; Buscetta, A.; Banks, N.; Skaletsky, H.; Godfrey, A. K.; Pham, T. T.; Hughes, J. F.; Brown, L. G.; Kruszka, P.; Lin, A. E.; Kastner, D. L.; Muenke, M.; Page, D. C.

10.1101/2024.03.18.585578 — genomics — Posted on 2024-03-19

1969 Canopy2: tumor phylogeny inference by bulk DNA and single-cell RNA sequencing

Weideman, A. M. K.; Wang, R.; Ibrahim, J. G.; Jiang, Y.

10.1101/2024.03.18.585595 — genomics — Posted on 2024-03-19

1970 The Genomic portrait of the Picene culture: new insights into the Italic Iron Age and the legacy of the Roman expansion in Central Italy.

Ravasini, F.; Niinemae, H.; Solnik, A.; de Gennaro, L.; Montinaro, F.; Hui, R.; Delpino, C.; Finocchi, S.; Giroldini, P.; Mei, O.; Cilli, E.; Hajiesmaeil, M.; Pistacchia, L.; Risi, F.; Giacometti, C.; Scheib, C. L.; Tambets, K.; Metspalu, M.; Cruciani, F.; D'Atanasio, E.; Trombetta, B.

10.1101/2024.03.18.585512 — genomics — Posted on 2024-03-19

1971 Gene-language models are whole genome representation learners

Naidenov, B.; Chen, C.

10.1101/2024.03.18.585642 — genomics — Posted on 2024-03-19

1972 Following The Evolutionary Paths Of Highly Specific Homophilic Adhesion Proteins

Wiseglass, G.; Rubinstein, R.

10.1101/2024.03.18.585463 — evolutionary biology — Posted on 2024-03-19

1973 Genomic insights on the potential role of the accessory genome in the emergence of a novel geographically restricted K. pneumoniae lineage as a high-risk clone

Bighi, N. S.; Freitas, F.; Morgado, S.; Cipriano, R.; Vicente, A. C. P.; Fonseca, E. L.

10.1101/2024.03.18.585244 — microbiology — Posted on 2024-03-19

1974 Identification of a Conserved B-Cell Epitope on the Capsid Protein of Porcine Circovirus Type 4

Fang, Z.; Sun, M.-X.; Cai, X.; An, T.-Q.; Tu, Y.; Wang, H.

10.1101/2024.03.18.585584 — microbiology — Posted on 2024-03-19

1975 Multi-Site Investigation of Gut Microbiota in CDKL5 Deficiency Disorder Mouse Models: Targeting Dysbiosis to Improve Neurological Outcomes

Damiani, F.; Giuliano, M. G.; Cornuti, S.; Putignano, E.; Tognozzi, A.; Suckow, V.; Kalscheuer, V. M.; Tognini, P.

10.1101/2024.03.19.581742 — neuroscience — Posted on 2024-03-19

1976 The role of rat prelimbic cortex in decision making

Palmer, J. A.; White, S. R.; Lopez, K. C.; Laubach, M.

10.1101/2024.03.18.585593 — neuroscience — Posted on 2024-03-19

1977 CRISPR-Cas9-assisted genome editing in E. coli elevates the frequency of unintended mutations

Widney, K. A.; Yang, D.-d.; Rusch, L. M.; Copley, S. D.

10.1101/2024.03.19.584922 — synthetic biology — Posted on 2024-03-19

1978 NONEXPRESSOR OF PATHOGENESIS-RELATED GENES control Huanglongbing tolerance by regulating immune balance in citrus plants

Sarkar, P.; El-Mohtar, C.; Turner, D.; Welker, S.; Robertson, C. J.; Orbovic, V.; Mou, Z.; Levy, A.

10.1101/2024.03.18.585579 — plant biology — Posted on 2024-03-19

1979 New specimens of Bunaia woodwardi, Clarke 1919 (Euchelicerata): A new member of Offacolidae providing insight supporting the Arachnomorpha

Lustri, L.; Antcliffe, J. B.; Gueriau, P.; Daley, A. C.

10.1101/2024.03.18.585490 — paleontology — Posted on 2024-03-19

1980 Assembly of mTORC3 involves binding of ETV7 to two separate sequences in the mTOR kinase domain.

Zhan, J.; Harwood, F. C.; Have, S. T.; Lamond, A. I.; Halder, P.; Kriwacki, R.; Grosveld, G. C.

10.1101/2024.03.19.583970 — cancer biology — Posted on 2024-03-19

1981 LarvaTagger: Manual and automatic tagging of Drosophila larval behaviour

Laurent, F.; Blanc, A.; May, L.; Gandara, L.; Cocanougher, B. T.; Jones, B. M. W.; Hague, P.; Barre, C.; Vestergaard, C. L.; Crocker, J.; Zlatic, M.; Jovanic, T.; Masson, J.-B.

10.1101/2024.03.18.585197 — bioinformatics — Posted on 2024-03-19

1982 Exploring structural diversity across the protein universe with The Encyclopedia of Domains

Lau, A. M. C.; Bordin, N.; Kandathil, S. M.; Sillitoe, I.; Waman, V. P.; Wells, J.; Orengo, C.; Jones, D. T.

10.1101/2024.03.18.585509 — bioinformatics — Posted on 2024-03-19

1983 Optimisation strategies for directed evolution without sequencing

James, J.; Towers, S.; Foerster, J.; Steel, H.

10.1101/2024.03.18.585521 — bioengineering — Posted on 2024-03-19

1984 Deciphering a beetle clock: individual and sex-dependent variation in daily activity patterns

R, R.; Prueser, T.; Schulz, N. K. E.; Mayer, P. M. F.; Ogueta, M.; Stanewsky, R.; Kurtz, J.

10.1101/2024.03.18.585527 — animal behavior and cognition — Posted on 2024-03-19

1985 Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer's Disease

Adeoye, T.; Shah, S. I.; Ullah, G.

10.1101/2024.03.15.585267 — genomics — Posted on 2024-03-19

1986 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons

Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.

10.1101/2022.08.18.504439 — ecology — Posted on 2024-03-19

1987 Distribution, ecology, and natural history of the recently rediscovered and critically endangered Santa Marta Sabrewing

Botero-Delgadillo, E.; Lara, C. E.; Vega, Y.; Santos, M. P.; Zarrate, D.; Cuervo, A. M.; Mittermeier, J. C.

10.1101/2024.03.18.581190 — ecology — Posted on 2024-03-19

1988 A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish

Coppola, U.; Kenney, J.; Waxman, J. S.

10.1101/2024.03.13.584759 — developmental biology — Posted on 2024-03-19

1989 A programmable and automated optical electrowetting-on-dielectric (oEWOD) driven platform for massively parallel and sequential processing of single cell assay operations

Welch, L. G.; Estranero, J.; Tourlomousis, P.; Wootton, R. C. R.; Radu, V.; Gonzalez-Fernandez;, C.; Puchtler, T. J.; Murzeau, C. M.; Dieckmann, N. M. G.; Shibahara, A.; Longbottom, B. W.; Bryant, C. E.; Talbot, E. L.

10.1101/2024.03.19.585693 — cell biology — Posted on 2024-03-19

1990 A low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics

King, E. S.; Stacey, A. E.; Scott, J. G.

10.1101/2024.03.08.584154 — microbiology — Posted on 2024-03-19

1991 Discovery of Eremiobacterota with nifH homologs in tundra soil

Pessi, I. S.; Delmont, T.; Zehr, J. P.; Hultman, J.

10.1101/2023.06.30.547195 — microbiology — Posted on 2024-03-19

1992 Disentangling the effects of hearing loss and age on amplitude modulation frequency selectivity

Regev, J.; Relano-Iborra, H.; Zaar, J.; Dau, T.

10.1101/2023.07.15.549131 — neuroscience — Posted on 2024-03-19

1993 Loss of Tumour Suppressor TMEM127 Drives RET-mediated Transformation Through Disrupted Membrane Dynamics

Walker, T. J.; Reyes-Alvarez, E.; Hyndman, B. D.; Sugiyama, M. G.; Oliveira, L. C. B.; Rekab, A. N.; Crupi, M. J. F.; Cabral-Dias, R.; Guo, Q.; Dahia, P. L. M.; Richardson, D. S.; Antonescu, C. N.; Mulligan, L. M.

10.1101/2023.06.28.546955 — cancer biology — Posted on 2024-03-19

1994 Twist - torsion coupling in beating axonemes

Striegler, M.; Friedrich, B. M.; Diez, S.; Geyer, V. F.

10.1101/2024.03.18.585533 — biophysics — Posted on 2024-03-19

1995 Emergence of ion-channel mediated electrical oscillations in E. coli biofilms

Akabuogu, E. U.; Martorelli, V.; Krasovec, R.; Roberts, I. S.; Waigh, T. A.

10.1101/2022.11.09.515771 — biophysics — Posted on 2024-03-19

1996 Jointly benchmarking small and structural variant calls with vcfdist

Dunn, T.; Zook, J. M.; Holt, J. M.; Narayanasamy, S.

10.1101/2024.01.23.575922 — bioinformatics — Posted on 2024-03-19

1997 Motor Hotspot Localization Based on Electroencephalography Using Convolutional Neural Network in Patients with Stroke

Choi, G.-Y.; Seo, J.-K.; Kim, K. T.; Chang, W. K.; Paik, N.-J.; Kim, W.-S.; Hwang, H.-J.

10.1101/2024.03.06.583618 — bioengineering — Posted on 2024-03-19

1998 Whole protein sequencing and quantification without proteolysis, terminal residue cleavage, or purification: A computational model

Sampath, G.

10.1101/2024.03.13.584825 — bioengineering — Posted on 2024-03-19

1999 Excess neonatal testosterone causes male-specific social and fear memory deficits in wild-type mice

Quinones-Labernik, P.; Blocklinger, K. L.; Bruce, M. R.; Ferri, S. L.

10.1101/2023.10.18.562939 — animal behavior and cognition — Posted on 2024-03-19

2000 Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression.

Pizzirusso, G.; Preka, E.; Goikolea, J.; Aguilar Ruiz, C.; Rodriguez Rodriguez, P.; Vazquez Cabrera, G.; Laterza, S.; Latorre-Leal, M.; Eroli, F.; Blomgren, K.; Maioli, S.; Nilsson, P.; Fragkopoulou, A.; Fisahn, A.; Arroyo-Garcia, L. E.

10.1101/2024.03.14.584993 — neuroscience — Posted on 2024-03-19

2001 A novel in vitro tubular model to recapitulate features of distal airways: the bronchioid

Maurat, E.; Raasch, K.; Leipold, A. M.; Henrot, P.; Zysman, M.; Prevel, R.; Trian, T.; Krammer, T.; Bergeron, V.; Thumerel, M.; Nassoy, P.; Berger, P.; Saliba, A.-E.; Andrique, L.; Recher, G.; Dupin, I.

10.1101/2023.12.06.569771 — physiology — Posted on 2024-03-19

2002 Evolution of phenotypic plasticity leads to tumor heterogeneity with implications for therapy

Syga, S.; Jain, H. P.; Krellner, M.; Hatzikirou, H.; Deutsch, A.

10.1101/2024.03.18.585460 — cancer biology — Posted on 2024-03-19

2003 Sequence-defined oligophosphoesters for selective inhibition of the KRAS G12D/RAF1 interaction

Claringbold, B.; Vance, S.; Paul, A. R.; Garrett, M. D.; Serpell, C. J.

10.1101/2024.03.12.584553 — cancer biology — Posted on 2024-03-19

2004 Variational inference for microbiome survey data with application to global ocean data

Mishra, A. K.; McNichol, J.; Fuhrman, J.; Blei, D.; Muller, C. L.

10.1101/2024.03.18.585474 — bioinformatics — Posted on 2024-03-19

2005 Molecular Mechanism of Condensin I Activation by KIF4A

Cutts, E. E.; Tetiker, D.; Kim, E.; Aragon, L.

10.1101/2024.03.19.585759 — biochemistry — Posted on 2024-03-19

2006 Moderate confirmation bias enhances collective decision-making in reinforcement-learning agents

Bergerot, C.; Barfuss, W.; Romanczuk, P.

10.1101/2023.11.21.568073 — animal behavior and cognition — Posted on 2024-03-19

2007 Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

Palma, A.; Ballarino, M.

10.1101/2024.03.18.585481 — genomics — Posted on 2024-03-19

2008 Expression dynamics of long non-coding RNAs during imaginal disc development and regeneration in Drosophila

Camilleri-Robles, C.; Amador, R.; Tiebe, M.; Teleman, A.; Serras, F.; Guigo, R.; Corominas, M.

10.1101/2024.03.19.585729 — developmental biology — Posted on 2024-03-19

2009 The RNA-dependent interactions of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.

Sztacho, M.; Cervenka, J.; Salovska, B.; Antiga, L.; Hoboth, P.; Hozak, P.

10.1101/2024.03.19.585734 — cell biology — Posted on 2024-03-19

2010 Intestinal tuft cells assemble a cytoskeletal superstructure composed of co-aligned actin bundles and microtubules

Silverman, J. B.; Krystofiak, E.; Caplan, L. R.; Lau, K. S.; Tyska, M. J.

10.1101/2024.03.19.585757 — cell biology — Posted on 2024-03-19

2011 Altered co-stimulatory and inhibitory receptors on monocyte subsets in patients with visceral leishmaniasis

Adem, E.; Yizengaw, E.; Mulaw, T.; Nibret, E.; Muller, I.; Takele, Y.; Kropf, P.

10.1101/2024.03.18.585473 — immunology — Posted on 2024-03-19

2012 Multi-way modelling of oral microbial dynamics and host-microbiome interactions during induced gingivitis

van der Ploeg, G. R.; Brandt, B.; Keijser, B.; van der Veen, M.; Volgenant, C.; Zaura, E.; Smilde, A.; Westerhuis, J.; Heintz-Buschart, A.

10.1101/2024.03.18.585469 — systems biology — Posted on 2024-03-19

2013 Dysregulated Ca2+ signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren's syndrome

Huang, K.-T.; Wagner, L. E.; Takano, T.; Lin, X.-X.; Bagavant, H.; Deshmukh, U.; Yule, D. I.

10.1101/2024.03.19.585719 — physiology — Posted on 2024-03-19

2014 Crosstalk between thrombospondin-1 and CD36 modulates platelet-RBC interaction limiting thrombosis and abdominal aneurysm formation

Krott, K. J.; Feige, T.; Bosbach, A.; Beele, A.; Krueger, I.; Reusswig, F.; Schickentanz-Dey, E.; Chadt, A.; Kelm, M.; Gerdes, N.; Pfeiler, S.; Jurk, K.; Kiouptsi, K.; Reinhardt, C.; Al-Hasani, H.; Kehrel, B.; Karray, S.; Schelzig, H.; Wagenhaueser, M.; Elvers, M.

10.1101/2024.03.18.585356 — pathology — Posted on 2024-03-19

2015 Mutating the arginine residue within the FRNK motif of HC-Pro yield highly attenuated strains that confer complete cross protection against telosma mosaic virus (TelMV) in passion fruit (Passiflora edulis)

Wang, L.; Shi, W.; Aziz, A.; Wang, X.; Liu, H.; Shen, W.; Wang, A.; Cui, H.; Dai, Z.

10.1101/2024.03.18.585366 — pathology — Posted on 2024-03-19

2016 Myc upregulates Ggct, γ-glutamylcyclotransferase to promote development of p53-deficient osteosarcoma

Ito, K.

10.1101/2024.03.18.585455 — cancer biology — Posted on 2024-03-19

2017 Characterization of the murine spine for spaceflight studies

Lim, S.; Veres, J. E.; Almeida, E. A.; O'Connell, G.

10.1101/2024.03.17.585438 — bioengineering — Posted on 2024-03-19

2018 Nine high-quality Anas genomes provide new insights into Anas evolution and domestication

Zhang, Z.; Ni, Z.; Li, T.; Ning, M.; Gao, C.; Hu, J.; Han, M.; Yang, J.; Wu, F.; Chen, L.; Lu, L.; Wu, Z.; Ai, H.; Huang, Y.

10.1101/2024.03.17.585367 — genomics — Posted on 2024-03-19

2019 Low effective population size but high heterozygosity revealed by SNP analyses in adult and juvenile Thuja plicata in UK Woodlands

Guillardin, L.; MacKay, J.; Kerr, G.; Glover, E.

10.1101/2024.03.18.585477 — genomics — Posted on 2024-03-19

2020 Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9

Eaton, J. D.; Board, J.; Davidson, L.; Estell, C.; West, S.

10.1101/2023.11.02.565285 — molecular biology — Posted on 2024-03-19

2021 Map based cloning of CT2 and the pilot functional exploration in abiotic stress

Wang, C.; Zheng, Q.; Gao, Y.; Guo, Z.; Zheng, L.; Yang, J.; Tang, J.; zheng, x.; Shi, Y.

10.1101/2024.03.17.585181 — molecular biology — Posted on 2024-03-19

2022 Granzyme B-based CAR T cells block metastasis by eliminating circulating tumor cells

Sun, B.; Guo, J.; Yang, D.; Hu, Q.; Ma, H.; Tian, P.; Liu, N.; Lv, L.; Yan, L.; Hao, D.; Fu, M.; Gou, H.; Cao, D.; Liu, D.; Chen, N.; SHI, P.; Li, W.; Zhao, X.

10.1101/2024.03.18.585442 — immunology — Posted on 2024-03-19

2023 High segregation and diminished global integration in large-scale brain functional networks enhances the perceptual binding of cross-modal stimuli

Singh, S. S.; Mukherjee, A.; Raghunathan, P.; Ray, D.; Banerjee, A.

10.1101/2020.09.02.276071 — neuroscience — Posted on 2024-03-19

2024 Normative growth modeling of brain morphology reveals neuroanatomical heterogeneity and biological subtypes in children with ADHD

Bu, X.; Zhao, Y.; Zheng, X.; Fu, Z.; Zhang, K.; Sun, X.; Cui, Z.; Xia, M.; Ma, L.; Liu, N.; Lu, J.; Zhao, G.; Ding, Y.; Deng, Y.; Wang, J.; Chen, R.; Zhang, H.; Men, W.; Wang, Y.; Gao, J.; Tan, S.; Sun, L.; Qin, S.; Tao, S.; Wang, Y.; Dong, Q.; Cao, Q.; Yang, L.; He, Y.

10.1101/2024.03.16.582202 — neuroscience — Posted on 2024-03-19

2025 Comprehensive evaluation of pipelines for diagnostic biomarkers of major depressive disorder using multi-site resting-state fMRI datasets

Takahara, Y.; Kashiwagi, Y.; Tokuda, T.; Yoshiomoto, J.; Sakai, Y.; Yamashita, A.; Yoshioka, T.; Takahashi, H.; Mizuta, H.; Kasai, K.; Kunimitsu, A.; Okada, N.; Itai, E.; Shinzato, H.; Yokoyama, S.; Masuda, Y.; Mitsuyama, Y.; Okada, G.; Okamoto, Y.; Itahashi, T.; Ota, H.; Hashimoto, R.-i.; Harada, K.; Yamagata, H.; Matsubara, T.; Matsuo, K.; Tanaka, S. C.; Imamizu, H.; Ogawa, K.; Momosaki, S.; Kawato, M.; Yamashita, O.

10.1101/2024.03.17.584538 — neuroscience — Posted on 2024-03-19

2026 Dysregulated Neurofluid Coupling as a New Noninvasive Biomarker for Primary Progressive Aphasia

Zeng, X.; Hua, L.; Zhao, Z.; Yuan, Z.

10.1101/2024.03.18.585468 — neuroscience — Posted on 2024-03-19

2027 An updated review of the marine ornamental fish trade in the European Union

Biondo, M. V.; Burki, R. P.; Aguayo, F.; Calado, R.

10.1101/2024.03.17.585413 — scientific communication and education — Posted on 2024-03-19

2028 ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma

Yu, V. Z.; So, S. S.; Lung, B. C.-c.; Hou, G. Z.; Wong, C. W.-y.; Chow, L. K.-y.; Chung, M. K.-y.; Wong, I. Y.-h.; Wong, C. L.-y.; Chan, D. K.-k.; Chan, F. S.-y.; Law, B. T.-t.; Xu, K.; Tan, Z. Z.; Lam, K.-o.; Lo, A. W.-i.; Lam, A. K.-y.; Kwong, D. L.-w.; Ko, J. M.-y.; Dai, W.; Law, S.; Lung, M. L.

10.1101/2024.03.17.585449 — cancer biology — Posted on 2024-03-19

2029 Dysregulation of cell state dynamics during early stages of serous endometrial carcinogenesis

Flesken-Nikitin, A.; Pirtz, M. G.; Ashe, C. S.; Ellenson, L. H.; Cosgrove, B. D.; Nikitin, A. Y.

10.1101/2024.03.15.585274 — cancer biology — Posted on 2024-03-19

2030 Biguanide-PROTACs: Modulating Mitochondrial Proteins in Pancreatic Cancer Cells

Vatte, J.; Bourdeau, V.; Ferbeyre, G.; Schmitzer, A.

10.1101/2024.03.17.585436 — cancer biology — Posted on 2024-03-19

2031 Defining focal neuroendocrine differentiation as a transcriptionally distinct form of prostate cancer pathology characterized by the expression of androgen receptors

Quezada Urban, R.; Keerthikumar, S.; Clark, A.; Wang, H.; Phipson, B.; Bakshi, A.; Ryan, A.; Thorne, H. J.; Taylor, R. A.; Lawrence, M. G.; Risbridger, G. P.; Toivanen, R.; Goode, D. L.

10.1101/2024.03.17.585125 — cancer biology — Posted on 2024-03-19

2032 GeneSurv: Multi-Gene Cancer Survival Analysis Tool

XU, Z.; Wu, J.; Shin, S.; Nguyen, L. K.

10.1101/2024.03.17.583882 — bioinformatics — Posted on 2024-03-19

2033 Nanoparticle-mediated delivery of peptide-based degraders enables targeted protein degradation

Ghosal, S.; Robertus, C.; Wang, J.; Chan, H. W.; Alamgir, A.; Almonte, J.; Alabi, C. A.

10.1101/2024.03.17.584721 — bioengineering — Posted on 2024-03-19

2034 Chromosome-level Subgenome-aware de novo Assembly of Saccharomyces bayanus Provides Insight into Genome Divergence after Hybridization

Gardner, C.; Chen, J.; Hadfield, C.; Lu, Z.; Debruin, D.; Zhan, Y.; Donlin, M.; Lin, Z.; Ahn, T.-H.

10.1101/2024.03.17.585453 — evolutionary biology — Posted on 2024-03-19

2035 DNA metabarcoding revealed how time and space do matter -sex does not- in the dietary variation of the endangered Duponts Lark

Zurdo, J.; Bustillo-de la Rosa, D.; Barrero, A.; Gomez-Catasus, J.; Reverter, M.; Perez-Granados, C.; Garcia, J. T.; Vinuela, J.; Dominguez, J. C.; Morales, M. B.; Traba, J.

10.1101/2024.03.17.585437 — ecology — Posted on 2024-03-19

2036 Changes in length-at-first return of a sea trout (Salmo trutta) population in northern France

Josset, Q.; Beaulaton, L.; Romakkaniemi, A.; Nevoux, M.

10.1101/2023.11.21.568009 — ecology — Posted on 2024-03-19

2037 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models

Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.; Kuemmerle, T.

10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-19

2038 Post-transcriptional RNA stabilization of telomere-proximal RNAs FRG2, DBET, D4Z4 at human 4q35 in response to genotoxic stress and D4Z4 macrosatellite repeat length.

Salsi, V.; Losi, F.; Salani, M.; Kaufman, P. D.; Tupler, R. G.

10.1101/2024.03.18.585486 — genetics — Posted on 2024-03-19

2039 Efficient test for deviation from Hardy Weinberg Equilibrium with known or ambiguous typing in highly polymorphic loci

Shkuri, O.; Israeli, S.; Tshuva, Y.; Maiers, M.; Louzoun, Y.

10.1101/2024.03.19.585658 — genetics — Posted on 2024-03-19

2040 Adipose tissue microvascular endothelial cells form a tight vascular barrier that selectively transcytoses fatty acid tracers

Schipper, R.; Ioannidou, A.; Maestri, A.; Baganha, F.; Werngren, O.; Oolofsson, P. S.; Malin, S. G.; Fisher, R. M.; Hagberg, C. E.

10.1101/2024.03.19.585709 — cell biology — Posted on 2024-03-19

2041 Development of covalent probes to capture Legionella pneumophila effector enzymes

van der Heden van Noort, G. J.; Kloet, M. S.; Mukhopadhyay, R.; Mukherjee, R.; Misra, M.; Jeong, M.; Talavera Ormeno, C. M. P.; Moutsiopoulou, A.; Tjokrodirijo, R. T. N.; van Veelen, P. A.; Shin, D.; Dikic, I.; Sapmaz, A.; Kim, R. Q.

10.1101/2024.03.19.585531 — cell biology — Posted on 2024-03-19

2042 Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels

Eiken, M. K.; Childs, C. J.; Brastrom, L. K.; Frum, T.; Plaster, E. M.; Shachaf, O.; Pfeiffer, S.; Levine, J. E.; Alysandratos, K.; Kotton, D. N.; Spence, J. R.; Loebel, C.

10.1101/2024.03.19.585720 — cell biology — Posted on 2024-03-19

2043 Loss of intermicrovillar adhesion impairs basolateral junctional complexes in transporting epithelia

Cencer, C. S.; Robinson, K. L.; Tyska, M. J.

10.1101/2024.03.19.585733 — cell biology — Posted on 2024-03-19

2044 Replication efficiencies of human cytomegalovirus-infected epithelial cells are dependent on source of virus production

Mokry, R. L.; Monti, C.; Rosas-Rogers, S.; Schumacher, M.; Dash, R. K.; Terhune, S. S.

10.1101/2024.03.19.585739 — microbiology — Posted on 2024-03-19

2045 Genomic and phenotypic imprints of microbial domestication on cheese starter cultures

Somerville, V.; Thierer, N.; Schmidt, R. S.; Roetschi, A.; Braillard, L.; Haueter, M.; Berthoud, H.; Shani, N.; von Ah, U.; Mazel, F.; Engel, P.

10.1101/2024.03.19.585705 — microbiology — Posted on 2024-03-19

2046 Multi-omics analysis of aggregative multicellularity

Edelbroek, B.; Orzechowski Westholm, J.; Bergquist, J.; Soderbom, F.

10.1101/2024.03.19.585704 — microbiology — Posted on 2024-03-19

2047 A packaging signal-binding protein regulates the assembly checkpoint of integrative filamentous phages

Yeh, T.-Y.; Feehley, M. C.; Feehley, P. J.; Ooi, V. Y.; Hung, Y.-Y.; Wang, S.-C.; Contreras, G. P.

10.1101/2024.03.19.585677 — microbiology — Posted on 2024-03-19

2048 The putative Type 4 secretion system effector BspD is involved in maintaining envelope integrity of the pathogen Brucella

Ketterer, M.; Chiquet, P.; Sedzicki, J.; Quebatte, M.; Dehio, C.

10.1101/2024.03.18.585630 — microbiology — Posted on 2024-03-19

2049 Adaptation of Pseudomonas aeruginosa to repeated invasion into a commensal competitor

Wheatley, R. M.; Shaw, L. P.; Shah, S.; Lindon, S.; MacLean, R. C.

10.1101/2024.03.19.585690 — microbiology — Posted on 2024-03-19

2050 RFW captures species-level full profile of metagenomic functions via integrating genome annotation information

Mi, K.; Liu, X.

10.1101/2024.03.19.585660 — microbiology — Posted on 2024-03-19

2051 Id1, Spp1 and Pak3 are biomarkers of Smad4 and TGF-β1 dependency in conditional intestinal adenoma, organoids and colorectal cancer.

Surakhy, M.; Matheson, J.; Barnes, D.; Carter, E.; Hughes, J.; Bühnemann, C.; Sanegre, S.; Morreau, H.; Metz, P.; Imianowski, C. J.; HASSAN, A. B.

10.1101/2024.03.15.584288 — cancer biology — Posted on 2024-03-19

2052 Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in African American and European American patients with TNBC

10.1101/2024.03.17.585428 — cancer biology — Posted on 2024-03-19

2053 Structural analysis of genetic variants of the human tumor suppressor Palb2 coiled-coil domain

Das, R.; Reddy, P. P.; Phale, A. P.

10.1101/2024.03.19.585655 — biophysics — Posted on 2024-03-19

2054 Concepts and methods for predicting viral evolution

Meijers, M.; Ruchnewitz, D.; Eberhardt, J.; Karmakar, M.; Łuksza, M.; Lässig, M.

10.1101/2024.03.19.585703 — biophysics — Posted on 2024-03-19

2055 Design principles for accurate folding of DNA origami

Aksel, T.; Navarro, E. J.; Fong, N.; Douglas, S. M.

10.1101/2024.03.18.585609 — biophysics — Posted on 2024-03-19

2056 All-atom protein sequence design based on geometric deep learning

Liu, J.; Guo, Z.; Zhang, C.; Lai, L.

10.1101/2024.03.18.585651 — biophysics — Posted on 2024-03-19

2057 Physical forces drive C. elegans embryonic deformation

Wang, T.; Ben Amar, M.

10.1101/2024.03.19.585678 — biophysics — Posted on 2024-03-19

2058 Energy landscapes of peptide-MHC binding

Collesano, L.; Luksza, M.; Lassig, M.

10.1101/2024.03.19.585687 — biophysics — Posted on 2024-03-19

2059 Metric Ion Classification (MIC): A deep learning tool for assigning ions and waters in cryo-EM and x-ray crystallography structures

Shub, L.; Liu, W.; Skiniotis, G.; Keiser, M. J.; Robertson, M. J.

10.1101/2024.03.18.585639 — biophysics — Posted on 2024-03-19

2060 pH-Sensitive Nanodroplets for Controlled Delivery of Berberine Chloride

Hao, S.; Wang, S.; Cao, J.; Xue, Z.; Luo, Z.; Wu, P.; Chen, G.

10.1101/2024.03.18.585497 — biophysics — Posted on 2024-03-19

2061 Transcription factors ERα and Sox2 have differing multiphasic DNA and RNA binding mechanisms

Hemphill, W. O.; Steiner, H. R.; Kominsky, J. R.; Wuttke, D. S.; Cech, T. R.

10.1101/2024.03.18.585577 — biophysics — Posted on 2024-03-19

2062 Tuning non-linear mechanics in collagen hydrogels modulates three dimensional cellular morphotypes

Enriquez Martinez, M. A.; Wang, Z.; Ju, R. J.; Turunen, P.; Mata, J.; Gilbert, E. P.; Lauko, J.; Stehbens, S. J.; Rowan, A. E.

10.1101/2024.03.18.585457 — biophysics — Posted on 2024-03-19

2063 GPCR surface creates a favorable pathway for membrane permeation of drug molecules

Gil Herrero, C.; Thallmair, S.

10.1101/2024.03.18.585530 — biophysics — Posted on 2024-03-19

2064 Phase Contrast Tomography (PCT)

Ma, Y.; Feng, W.; Lei, Y.; Ma, L.; Zheng, J.; An, S.; Liu, M.; Gao, P.

10.1101/2024.03.17.585445 — biophysics — Posted on 2024-03-19

2065 E. coli ClpB is a Robust and Processive Protein Unfoldase

Banwait, J. K.; Islam, L.; Lucius, A. L.

10.1101/2024.03.18.584833 — biophysics — Posted on 2024-03-19

2066 Expanded methylome and quantitative trait loci detection by long-read profiling of personal DNA

Groza, C.; Ge, B.; Cheung, W. A.; Pastinen, T.; Bourque, G.

10.1101/2024.03.17.585420 — bioinformatics — Posted on 2024-03-19

2067 Novel, postnatal manifestation of an epidermal barrier defect in a mouse model of isolated sulfite oxidase deficiency

Johannes, L.; Ruebsam, M.; Loehr, J.; Ding, X.; Eming, S.; Niessen, C. M.; Schwarz, G.

10.1101/2024.03.14.584870 — biochemistry — Posted on 2024-03-19

2068 Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

Stander, S.; Reboul, C. F.; Lee, S. N.; Williams, D.; Chandler, P. G.; Costa, M. G.; Hoke, D. E.; Jimma, J. D.; Fodor, J.; Fenalti, G.; Mannering, S. I.; Porebski, B. T.; Schofield, P.; Christ, D.; Buckle, M.; McGowan, S.; Elmlund, D.; Rand, K. D.; Buckle, A. M.

10.1101/2024.03.18.585568 — biochemistry — Posted on 2024-03-19

2069 "Stability and affinity evaluation of aptamers as a biorecognition system for testosterone and its analogs".

Medina-Benitez, A.; Garcia-Alonso, C. A.; Fragoso-Rodriguez, R.; Torres-Huerta, A. L.; Antonio-Perez, A.

10.1101/2024.03.18.585618 — biochemistry — Posted on 2024-03-19

2070 Multi-substrate specificity shaped the complex evolution of the aminotransferase family across the tree of life

Koper, K.; Han, S.-W.; Kothadia, R.; Salamon, H.; Yoshikuni, Y.; Maeda, H. A.

10.1101/2024.03.19.585368 — biochemistry — Posted on 2024-03-19

2071 The somatic mutation landscape of normal gastric epithelium

Coorens, T. H. H.; Collord, G.; Jung, H.; Wang, Y.; Moore, L.; Hooks, Y.; Mahbubani, K.; Saeb-Parsy, K.; Campbell, P. J.; Martincorena, I.; Leung, S. Y.; Stratton, M. R.

10.1101/2024.03.17.585238 — genomics — Posted on 2024-03-19

2072 Geographical distribution, disease association and diversity of Klebsiella pneumoniae KL and O antigens in India: roadmap for vaccine development

Shamanna, V.; Srinivas, S.; Couto, N.; Nagaraj, G.; Sajankila, S. P.; Krishnappa, H. G.; Kumar, K. A.; Aanensen, D.; Lingegowda, R. K.; GHRU India Consortium,

10.1101/2024.03.15.585133 — genomics — Posted on 2024-03-19

2073 Large-Scale Assessment of the Iranian population structure of Mitochondrial and Y-chromosome Haplogroups

Mazaheri, N.; Ghahremani, A.; Babazadeh, M.; Motahari, S. A.; NashtaAli, D.

10.1101/2024.03.14.585067 — genetics — Posted on 2024-03-19

2074 Transfer and Capture of Envelope Protein Receptor-Binding Domains in the Retroviruses

Hotzel, I.

10.1101/2024.03.17.585361 — evolutionary biology — Posted on 2024-03-19

2075 Ornamental radiance as a defence against mimicry at the monogamy-polygyny interface.

Crompton, A.

10.1101/2024.03.17.585419 — evolutionary biology — Posted on 2024-03-19

2076 A numbers game: Mosquito-based arbovirus surveillance in two distinct geographic regions of Latin America

Mojica, J.; Arevalo, V.; Juarez, J. G.; Galarza, X.; Gonzalez, K.; Carrazco-Montalvo, A.; Suazo, H.; Harris, E.; Coloma, J.; Ponce, P.; Balmaseda, A.; Cevallos, V.

10.1101/2024.03.15.585246 — ecology — Posted on 2024-03-19

2077 Sex-dependent, lateralized engagement of anterior insular cortex inputs to thedorsolateral striatum in binge alcohol drinking

Haggerty, D. L.; Atwood, B.

10.1101/2023.08.23.554484 — neuroscience — Posted on 2024-03-19

2078 A salmon fish model reveals genetic signals in brain associated with early maturation

Pashay Ahi, E.; Verta, J.-P.; Kurko, J.; Ruokolainen, A.; Singh, P.; Debes, P. V.; Erkinaro, J.; Primmer, C. R.

10.1101/2024.03.18.585557 — genetics — Posted on 2024-03-19

2079 High-resolution genomic ancestry reveals mobility in early medieval Europe

Speidel, L.; Silva, M.; Booth, T.; Raffield, B.; Anastasiadou, K.; Barrington, C.; Gotherstrom, A.; Heather, P.; Skoglund, P.

10.1101/2024.03.15.585102 — evolutionary biology — Posted on 2024-03-19

2080 Maternal body condition affects the response of larval spined toads' faecal microbiome to a widespread contaminant

Tartu, S.; Pollet, N.; Clavereau, I.; Bouchard, G.; Brischoux, F.

10.1101/2023.12.18.572122 — ecology — Posted on 2024-03-19

2081 Temporal dynamics and maturation of resting-state activity in preterm infants

Adibpour, P.; Nasser, H.; Pedoux, A.; Devisscher, L.; Elbaz, N.; Ghozland, C.; Hinnekens, E.; Neumane, S.; Kabdebon, C.; Lefebvre, A.; Kaminska, A.; Hertz-Pannier, L.; Heneau, A.; Sibony, O.; Alison, M.; Delanoe, C.; Delorme, R.; Barbu-Roth, M.; Biran, V.; Dubois, J.

10.1101/2024.03.19.585608 — neuroscience — Posted on 2024-03-19

2082 The neurodevelopmental trajectory of beta band oscillations: an OPM-MEG study

Rier, L.; Rhodes, N.; Pakenham, D.; Boto, E.; Holmes, N.; Hill, R. M.; Reina Rivero, G.; Shah, V.; Doyle, C.; Osborne, J.; Bowtell, R. W.; Taylor, M.; Brookes, M. J.

10.1101/2024.01.04.573933 — neuroscience — Posted on 2024-03-19

2083 Optimized dCas9 Transcription Activators for Plants

Zinselmeier, M.; Casas-Mollano, J. A.; Cors, J.; Sychla, A.; Heinsch, S.; Voytas, D.; Smanski, M.

10.1101/2022.06.10.495638 — plant biology — Posted on 2024-03-19

2084 Multiple paralogues and recombination mechanisms drive the high incidence of 22q11.2 Deletion Syndrome

Vervoort, L.; Dierckxsens, N.; Sousa Santos, M.; Meynants, S.; Souche, E.; Cools, R.; Heung, T.; Devriendt, K.; Peeters, H.; Mcdonald-mcginn, D.; Swillen, A.; Breckpot, J.; Emanuel, B. S.; Van Esch, H.; Bassett, A. S.; Vermeesch, J. R.

10.1101/2024.03.14.585046 — genetics — Posted on 2024-03-19

2085 Dysfunctional β-cell longevity in diabetes relies on high energy conservation and positive epistasis

Raval, K. H.; Jamshidi, N.; Seyran, B. S.; Salwinski, L.; Pillai, R. K.; Yang, L.; Ma, F.; Pellegrini, M.; Shin, J.; Yang, X.; Tudzarova, S.

10.1101/2024.03.18.585508 — cell biology — Posted on 2024-03-19

2086 Transformation of the drug ibuprofen by Priestia megaterium: Reversible glycosylation and generation of hydroxylated metabolites

Hinzke, T.; Schlüter, R.; Mikolasch, A.; Zühlke, D.; Müller, P.; Riedel, K.; Lalk, M.; Becher, D.; Sheikany, H.; Schauer, F.

10.1101/2024.03.18.585558 — microbiology — Posted on 2024-03-19

2087 2-oxoglutarate triggers assembly of active dodecameric Methanosarcina mazei glutamine synthetase

Herdering, E.; Reif-Trauttmansdorff, T.; Kumar, A.; Habenicht, T.; Hochberg, G.; Bohn, S.; Schuller, J.; Schmitz, R. A.

10.1101/2024.03.18.585516 — microbiology — Posted on 2024-03-19

2088 Establishing synthetic ribbon-type active zones in a heterologous expression system

Kapoor, R.; Schwenzer, N.; Dresbach, T.; Lehnart, S.; Moser, T.

10.1101/2024.03.18.585517 — neuroscience — Posted on 2024-03-19

2089 Intra-species quantification reveals differences in activity and sleep levels in the yellow fever mosquito, Aedes aegypti

Ajayi, O.; Susanto, E. E.; Wang, L.; Kennedy, J.; Ledezma, A.; Harris, A.; Smith, E. S.; Chakraborty, S.; Wynne, N. E.; Sylla, M.; Akorli, J.; Otoo, S.; Rose, N. H.; Vinauger, C.; Benoit, J. B.

10.1101/2024.03.16.585223 — physiology — Posted on 2024-03-19

2090 Presynaptic Rac1 in the hippocampus selectively regulates working memory

Kim, J.; Bustamante, E.; Sotonyi, P.; Maxwell, N.; Parameswaran, P.; Kent, J. K.; Wetsel, W. C.; Soderblom, E. J.; Racz, B.; Soderling, S. H.

10.1101/2024.03.18.585488 — animal behavior and cognition — Posted on 2024-03-19

2091 Deciphering the Influence of Socioeconomic Status on Brain Structure: Insights from Mendelian Randomization

Xia, C.; Lu, Y.; Zhou, Z.; Marchi, M.; Kweon, H.; Ning, Y.; Liewald, D. C. M.; Anderson, E. L.; Koellinger, P. D.; Cox, S. R.; Boks, M. P.; Hill, W. D.

10.1101/2024.03.13.584410 — genetics — Posted on 2024-03-19

2092 miR-146a-5p mediates inflammation-induced β cell mitochondrial dysfunction and apoptosis

Krishnan, P.; Branco, R. C. S.; Weaver, S. A.; Chang, G.; Lee, C.-C.; Syed, F.; Evans-Molina, C.

10.1101/2024.03.18.585543 — molecular biology — Posted on 2024-03-19

2093 Partially observable Markov models inferred using statistical tests reveal context-dependent syllable transitions in Bengalese finch songs

Lu, J.; Surendralal, S.; Bouchard, K. E.; Jin, D. Z.

10.1101/2022.11.15.516592 — neuroscience — Posted on 2024-03-19

2094 Social navigation: distance and grid-like codes support navigation of abstract social space in the human brain

Liang, Z.; Wu, S.; Wu, J.; Wang, W.-X.; Qin, S.; Liu, C.

10.1101/2023.05.12.538784 — neuroscience — Posted on 2024-03-19

2095 Human spermatogonial stem cells retain states with a foetal-like signature

Bush, S. J.; Nikola, R.; Han, S.; Suzuki, S.; Yoshida, S.; Simons, B. D.; Goriely, A.

10.1101/2024.03.18.585628 — cell biology — Posted on 2024-03-19

2096 The 3'-untranslated regions of yeast ribosomal protein mRNAs determine paralog incorporation into ribosomes and recruit factors necessary for specialized functions

Singh, R.; Crawford, R. A.; Mall, D. P.; Pavitt, G. D.; Gerst, J. E.

10.1101/2024.03.18.585503 — cell biology — Posted on 2024-03-19

2097 GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding

Zou, J.; Jiang, M.; Xiao, R.; Sun, H.; Liu, H.; Peacock, T.; Tu, S.; Chen, T.; Guo, J.; Zhao, Y.; Barclay, W.; Xie, S.; Zhou, H.

10.1101/2024.03.18.585644 — microbiology — Posted on 2024-03-19

2098 Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein

Noone, D.; Isendoorn, M.; Hamers, S.; Keizer, M.; Wulffele, J. T.; van der Velden, T.; Dijkstra, D.; Trouw, L.; Filippov, D.; Sharp, T.

10.1101/2024.03.18.585147 — immunology — Posted on 2024-03-19

2099 ANKRD55 interacts with an IFT-B-like complex in microglia

Mena, J.; Navarro, R. T.; Diez-Garcia, J.; Azkargorta, M.; Aldekoa, A.; Fiat, A.; Ugidos-Damboriena, N.; Lindskog, C.; Pampliega, O.; Alloza, I.; Katoh, Y.; Nakayama, K.; Elortza, F.; Vandenbroeck, K.

10.1101/2024.03.18.584613 — immunology — Posted on 2024-03-19

2100 A web-based histology atlas for the freshwater Cladocera species Daphnia magna

Ngu, M. S.; Vanselow, D. X.; Zaino, C. R.; Lin, A. Y.; Copper, J. E.; Beaton, M.; Orsini, L.; Colbourne, J. K.; Cheng, K. C.; Ang, K. C.

10.1101/2022.03.09.483544 — zoology — Posted on 2024-03-19

2101 Widespread impact of natural genetic variations in CRISPR/Cas9 outcomes

Li, V. R.; Tadych, A.; Wong, A. K.; Zhang, Z.

10.1101/2023.09.26.559657 — bioengineering — Posted on 2024-03-19

2102 Metabolic priming of GD2 TRAC-CAR T cells during manufacturing promotes memory phenotypes while enhancing persistence

Cappabianca, D.; Pham, D.; Forsberg, M. H.; Bugel, M.; Tommasi, A.; Lauer, A.; Vidugiriene, J.; Hrdlicka, B.; McHale, A.; Sodji, Q.; Skala, M. C.; Capitini, C. M.; Saha, K.

10.1101/2024.01.31.575774 — bioengineering — Posted on 2024-03-19

2103 ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6 specific nanobody restricts M. tuberculosis growth in macrophages

Bates, T. A.; Trank-Greene, M.; Nguyenla, X.; Anastas, A.; Gurmessa, S.; Merutka, I. R.; Dixon, S. D.; Shumate, A.; Groncki, A. R.; Parson, M. A.; Ingram, J. R.; Barklis, E.; Burke, J. E.; Shinde, U.; Ploegh, H. L.; Tafesse, F. G.

10.1101/2023.08.16.553641 — biochemistry — Posted on 2024-03-19

2104 Single-cell genomics and regulatory networks for 388 human brains

10.1101/2024.03.18.585576 — genomics — Posted on 2024-03-19

2105 Post-GWAS functional analyses of CNTNAP5 suggests its role in glaucomatous neurodegeneration

Chakraborty, S.; Sarma, J.; Roy, S. S.; Mitra, S.; Bagchi, S.; Das, S.; Saha, S.; Mahapatra, S.; Bhattacharjee, S.; Maulik, M.; Acharya, M.

10.1101/2024.03.14.583830 — genetics — Posted on 2024-03-19

2106 Long-term dynamics of adaptation to a warming environment is dependent on historical background

Antunes, M. A.; Grandela, A.; Matos, M.; Simoes, P.

10.1101/2024.02.15.580572 — evolutionary biology — Posted on 2024-03-19

2107 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years

Bougiouri, K.; Charlton, S.; Harris, A.; Carmagnini, A.; Piliciauskiene, G.; Feuerborn, T. R.; Scarsbrook, L.; Tabadda, K.; Blazevicius, P.; Parker, H. G.; Gopalakrishnan, S.; Larson, G.; Ostrander, E. A.; Irving-Pease, E. K.; Frantz, L. A. F.; Racimo, F.

10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-03-19

2108 Flower size evolution in the Southwest Pacific

Ciarle, R.; Burns, K. C.; Mologni, F.

10.1101/2023.12.12.571326 — evolutionary biology — Posted on 2024-03-19

2109 Similar enzymatic functions in distinct bioluminescence systems: Evolutionary recruitment of sulfotransferases in ostracod light organs

Lau, E. S.; Goodheart, J. A.; Anderson, N. T.; Liu, V. L.; Mukherjee, A.; Oakley, T. H.

10.1101/2023.04.12.536614 — evolutionary biology — Posted on 2024-03-19

2110 Cardiac Outflow tract septation defects in a DiGeorge syndrome model respond to Minoxidil treatment.

Aurigemma, I.; Ferrentino, R.; Krishnan, V. P.; Lanzetta, O.; Angelini, C.; Illingworth, E.; Baldini, A.

10.1101/2024.03.18.585569 — developmental biology — Posted on 2024-03-19

2111 Electrical Impedance Spectroscopy Quantifies Skin Barrier Function in Organotypic In Vitro Epidermis Models

van den Brink, N. J. M.; Pardow, F.; Meesters, L. D.; van Vlijmen-Willems, I.; Rodijk-Olthuis, D.; Niehues, H.; Jansen, P. A. M.; Roelofs, S. H.; Brewer, M. G.; van den Bogaard, E. H.; Smits, J. P. H.

10.1101/2024.03.18.585587 — developmental biology — Posted on 2024-03-19

2112 Multiplexed DNA-PAINT Imaging of the Heterogeneity of Late Endosome/Lysosome Protein Composition

Bond, C.; Hugelier, S.; Xing, J.; Sorokina, E. M.; Lakadamyali, M.

10.1101/2024.03.18.585634 — cell biology — Posted on 2024-03-19

2113 Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections

Lasaviciute, G.; Tariq, K.; Sugathan, A.; Quin, J. E.; Bujila, I.; Skorokhod, O.; Troye-Blomberg, M.; Sverremark-Ekstrom, E.; Ostlund Farrants, A.-K.

10.1101/2024.03.18.585548 — cell biology — Posted on 2024-03-19

2114 Rapid High-Throughput Isolation and purification of Chicken Myoblasts Based on Deterministic Lateral Displacement Microfluidic Chips

Gu, L.; Liu, H.; Wang, L.; Fan, H.; Zheng, X.; Xu, T.; Jiang, Q.; Zhou, T.; Shi, L.

10.1101/2024.03.17.585435 — cell biology — Posted on 2024-03-19

2115 A random mutagenesis screen enriched for missense mutations in bacterial effector proteins.

Urbanus, M. L.; Zheng, T. M.; Khusnutdinova, A. N.; Banh, D.; Mount, H. O.; Gupta, A.; Stogios, P. J.; Savchenko, A.; Isberg, R. R.; Yakunin, A. F.; Ensminger, A. W.

10.1101/2024.03.14.585084 — microbiology — Posted on 2024-03-19

2116 Developmental pyrethroid exposure disrupts folate metabolism in mouse brain

Curtis, M. A.; Saferin, N.; Nguyen, J. H.; Imami, A. S.; Neifer, K. L.; Miller, G. W.; Burkett, J. P.

10.1101/2023.10.13.562226 — neuroscience — Posted on 2024-03-19

2117 Trading acyls and swapping sugars: metabolic innovations in Solanum trichomes

Fiesel, P. D.; Kerwin, R. A.; Jones, A. D.; Last, R. L.

10.1101/2023.06.05.542877 — plant biology — Posted on 2024-03-19

2118 Fluid Shear Stress-Induced Changes in Megalin Trafficking Enhance Endocytic Capacity in Proximal Tubule Cells

Lackner, E. M.; Cowan, I. A.; Long, K. R.; Weisz, O. A.; Shipman, K. E.

10.1101/2024.02.22.581213 — physiology — Posted on 2024-03-19

2119 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma

Curry, R. N.; Ma, Q.; McDonald, M. F.; Ko, Y.; Srivastava, S.; Chin, P.-S.; He, P.; Lozzi, B.; Aiba, I.; Meyer, J.; Jing, J.; Wang, S.; Harmanci, A. O.; Athukuri, P.; Noebels, J.; Arenkiel, B.; Jiang, X.; Deneen, B.; Rao, G.; Serin Harmanci, A.

10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-19

2120 Tumor microenvironmental determinants of high-risk DCIS progression

Glencer, A.; Ramalingam, K.; Schindler, N.; Mori, H.; Ghule, P.; Lee, K. C.; Nachmanson, D.; Officer, A.; Harismendy, O.; Stein, J. L.; Stein, G.; Weaver, D.; Yau, C.; Hirst, G. L.; Campbell, M. J.; Esserman, L. J.; Borowsky, A. D.

10.1101/2023.12.01.569676 — cancer biology — Posted on 2024-03-19

2121 Cryo-EM structures of Kv1.2 potassium channels, conducting and non-conducting

Wu, Y.; Yan, Y.; Yang, Y.; Bian, S.; Rivetta, A.; Allen, K.; Sigworth, F. J.

10.1101/2023.06.02.543446 — biophysics — Posted on 2024-03-19

2122 Numerical modeling of senile plaque development under conditions of limited diffusivity of amyloid-β monomers

Kuznetsov, A. V.

10.1101/2024.01.09.574935 — biophysics — Posted on 2024-03-19

2123 Lateral Flow Assays Biotesting by Utilizing Plasmonic Nanoparticles Made of Inexpensive Metals - Replacing Colloidal Gold

Bahamondes Lorca, V. A.; Avalos-Ovando, O. R.; Sikeler, C.; Ijäs, H.; Santiago, E. Y.; Skelton, E.; Wang, Y.; Yang, R.; Cimatu, K. L. A.; Baturina, O.; Wang, Z.; Liu, J.; Slocik, J. M.; Wu, S.; Ma, D.; Pastukhov, A. I.; Kabashin, A.; Kordesch, M. E.; Govorov, A.

10.1101/2024.01.08.574723 — biophysics — Posted on 2024-03-19

2124 sincFold: end-to-end learning of short- and long-range interactions in RNA secondary structure

Bugnon, L. A.; Di Persia, L.; Gerard, M.; Raad, J.; Prochetto, S.; Fenoy, E.; Chorostecki, U.; Ariel, F.; Stegmayer, G.; Milone, D. H.

10.1101/2023.10.10.561771 — bioinformatics — Posted on 2024-03-19

2125 Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

Koren, S.; Bao, Z.; Guarracino, A.; Ou, S.; Goodwin, S.; Jenike, K. M.; Lucas, J.; McNulty, B.; Park, J.; Rautianinen, M.; Rhie, A.; Roelofs, D.; Schneiders, H.; Vrijenhoek, I.; Nijbroek, K.; Ware, D.; Schatz, M. C.; Garrison, E.; Huang, S.; McCombie, W. R.; Miga, K. H.; Wittenberg, A. H. J.; Phillippy, A. M.

10.1101/2024.03.15.585294 — bioinformatics — Posted on 2024-03-19

2126 Multiplexed dynamic control of temperature to probe and observe mammalian cells.

Benman, W.; Iyengar, P.; Mumford, T.; Huang, Z.; Bugaj, L.

10.1101/2024.02.18.580877 — bioengineering — Posted on 2024-03-19

2127 Unraveling a novel dual-function regulatory element showing epistatic interaction with a variant that escapes genome-wide association studies.

Adjemout, M.; Nisar, S.; Escandell, A.; Huu, H. T. N.; Torres, M.; Thiam, A.; Manosalva, I.; Mbengue, B.; Dieye, A.; Spicuglia, S.; Rihet, P.; Marquet, S.

10.1101/2024.03.18.585566 — genomics — Posted on 2024-03-19

2128 Transcriptional Determinism and Stochasticity Contribute to the Complexity of Autism Associated SHANK Family Genes

Lu, X.; Ni, P.; Suarez-Meade, P.; Yu, M.; Forrest, E. N.; Wang, G.; Wang, Y.; Quinones-Hinojosa, A.; Gerstein, M.; Jiang, Y.-h.

10.1101/2024.03.18.585480 — genetics — Posted on 2024-03-19

2129 Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC

Zhang, H.; Peyton, L. L.; McCarroll, A. G.; Guerrerro, S. D. d. L.; Zhang, S.; Gowda, P.; Sirkin, D. J. M.; El Achwah, M.; Duhe, A.; Wood, W. G.; Jamison, B.; Tracy, G.; Pollak, R.; Hart, R. P.; Pato, C. N.; Mulle, J. G.; Sanders, A. R.; Pang, Z. P.; Duan, J.

10.1101/2024.03.18.585542 — genetics — Posted on 2024-03-19

2130 Selection shapes the genomic landscape of introgressed ancestry in a pair of sympatric sea urchin species

Glasenapp, M.; Pogson, G.

10.1101/2023.12.01.566927 — evolutionary biology — Posted on 2024-03-19

2131 First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: Dispelling previous anecdotes

Lardeux, F.; Bousses, P.; Tejerina-Lardeux, R.; Berger, A.; Barnabe, C.; Garcia, L.

10.1101/2024.03.14.585027 — ecology — Posted on 2024-03-19

2132 Deciphering novel TCF4-driven mechanisms underlying a common triplet repeat expansion-mediated disease

Bhattacharyya, N.; Chai, N.; Hafford-Tear, N. J.; Sadan, A. N.; Szabo, A.; Zarouchlioti, C.; Jedlickova, J.; Leung, S. K.; Liao, T.; Dudakova, L.; Skalicka, P.; Parekh, M.; Moghul, I.; Jeffries, A. R.; Cheetham, M. E.; Muthusamy, K.; Hardcastle, A. J.; Pontikos, N.; Liskova, P.; Tuft, S. J.; Davidson, A. E.

10.1101/2023.03.29.534731 — molecular biology — Posted on 2024-03-19

2133 PPFlow: Target-aware Peptide Design with Torsional Flow Matching

Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.

10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-03-19

2134 Primary nasal viral infection rewires the tissue-scale memory response

Kazer, S. W.; Match, C. M.; Langan, E. M.; Messou, M.-A.; LaSalle, T. J.; O'Leary, E.; Marbourg, J.; Naughton, K.; von Andrian, U. H.; Ordovas-Montanes, J.

10.1101/2023.05.11.539887 — immunology — Posted on 2024-03-19

2135 Neurophysiology of perceptual decision-making and its alterations in attention deficit hyperactivity disorder (ADHD)

Biabani, M.; Walsh, K.; Zhou, S.-H.; Wagner, J.; Johnstone, A.; Paterson, J.; Johnson, B. P.; Loughnane, G. M.; O'Connell, R. G.; Bellgrove, M. A.

10.1101/2023.12.04.569762 — neuroscience — Posted on 2024-03-19

2136 Function of C. elegans neurons from synaptic connectivity

Emmons, S. W.

10.1101/2024.03.08.584145 — neuroscience — Posted on 2024-03-19

2137 pipesnake : Generalized software for the assembly and analysis of phylogenomic datasets from conserved genomic loci

Brennan, I. G.; Singhal, S.; Al Bkhetan, Z.

10.1101/2024.02.13.580223 — bioinformatics — Posted on 2024-03-18

2138 Development and Characterization of a low intensity vibrational system for microgravity studies

Khan, O. M.; Gasperini, W.; Neccessary, C.; Jacobs, Z.; Perry, S.; Kuehl, P.; Nelson, K.; Gamble, P.; DeLeon, M.; Howard, S.; Zavala, A.; Farach-Carson, M. C.; Blaber, E. A.; Wu, D.; Satici, A.; Uzer, G.

10.1101/2023.11.20.567870 — bioengineering — Posted on 2024-03-19

2139 Supramolecular complexes of GCAP1: towards the development of effective biologics for inherited retinal dystrophies

Biasi, A.; Marino, V.; Dal Cortivo, G.; Dell'Orco, D.

10.1101/2024.03.07.583919 — biochemistry — Posted on 2024-03-18

2140 Cohesin mediated loop extrusion from active enhancers form chromatin jets in C. elegans

Kim, J.; Wang, H.; Ercan, S.

10.1101/2023.09.18.558239 — genomics — Posted on 2024-03-19

2141 Epigenetic information loss is a common feature of multiple diseases and aging

Sagy, N.; Chang, C.; Gal, M.; Bar, D. Z.

10.1101/2023.05.07.539727 — molecular biology — Posted on 2024-03-19

2142 Bacteria Are a Major Determinant of Orsay Virus Transmission and Infection in Caenorhabditis elegans

Vassallo, B. G.; Scheidel, N.; Fischer, S. E. J.; Kim, D. H.

10.1101/2023.09.05.556377 — microbiology — Posted on 2024-03-18

2143 VaxSeer: Selecting influenza vaccines through evolutionary and antigenicity models

Shi, W.; Wohlwend, J.; Wu, M.; Barzilay, R.

10.1101/2023.11.14.567037 — immunology — Posted on 2024-03-18

2144 Distributed representations of behaviorally-relevant object dimensions in the human visual system

Contier, O.; Baker, C. I.; Hebart, M. N.

10.1101/2023.08.23.553812 — neuroscience — Posted on 2024-03-18

2145 Foveolar drusen decrease fixation stability in presymptomatic AMD

Murari, J.; Gautier, J.; Daout, J.; Krafft, L.; Senee, P.; Mece, P.; Seiple, W.; Grieve, K.; Sheynikhovich, D.; Meimon, S.; Paques, M.; Arleo, A.

10.1101/2023.10.09.560481 — neuroscience — Posted on 2024-03-18

2146 Embryonic origins of forebrain oligodendrocytes revisited by combinatorial genetic fate mapping

Cai, Y.; Zhao, Z.; Shi, M.; Zheng, M.; Gong, L.; He, M.

10.1101/2024.01.23.576886 — neuroscience — Posted on 2024-03-18

2147 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making

Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.

10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-03-18

2148 Cortical Face-Selective Responses Emerge Early in Human Infancy

Kosakowski, H. L.; Cohen, M. A.; Herrera, L.; Nichoson, I.; Kanwisher, N. G.; Saxe, R.

10.1101/2021.12.04.471085 — neuroscience — Posted on 2024-03-19

2149 Endocannabinoid and neuroplasticity-related changes as susceptibility factors in a rat model of posttraumatic stress disorder

Szente, L.; Balla, G. Y.; Varga, Z. K.; Toth, B.; Biro, L.; Balogh, Z.; Hill, M. N.; Toth, M.; Mikics, E.; Aliczki, M.

10.1101/2024.03.06.583339 — neuroscience — Posted on 2024-03-19

2150 Effects of Feed Processing Type, Protein Source, and Environmental Salinity on Litopenaeus vannamei Feeding Behaviour

Moss, A. S.; Brooker, A. J.; Ozioko, S.; Nederlof, M.; Debnath, S.; Schrama, J.

10.1101/2024.03.14.584959 — zoology — Posted on 2024-03-18

2151 Analysis of science journalism reveals gender and regional disparities in coverage

Davidson, N. R.; Greene, C. S.

10.1101/2021.06.21.449261 — scientific communication and education — Posted on 2024-03-18

2152 The Chloroplast RNA Binding Protein CP29A supports rbcL expression during cold acclimation

Lenzen, B.; Roesch, F.; Ruwe, H.; Kachariya, N.; Legen, J.; Sattler, M.; Small, I. D.; Schmitz-Linneweber, C.

10.1101/2023.11.24.568587 — plant biology — Posted on 2024-03-18

2153 The contribution of movement to social network structure and spreading dynamics under simple and complex transmission

Chimento, M.; Farine, D. R.

10.1101/2024.02.09.579705 — animal behavior and cognition — Posted on 2024-03-18

2154 Age-specificity in territory quality and spatial structure in a wild bird population

Woodman, J. P.; Firth, J. A.; Cole, E. F.; Sheldon, B. C.

10.1101/2024.03.11.584379 — ecology — Posted on 2024-03-18

2155 Developmental Regulation of Alternative Polyadenylation in an Adult Stem Cell Lineage

Gallicchio, L.; Reis Matias, N.; Morales-Polanco, F.; Nava, I.; Stern, S.; Zeng, Y.; Fuller, M. T.

10.1101/2024.03.18.585561 — developmental biology — Posted on 2024-03-18

2156 RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses

Rahjouei, A.; Kabrani, E.; Berruezo-Llacuna, M.; Altwasser, R.; Delgado-Benito, V.; Pavri, R.; Di Virgilio, M.

10.1101/2023.07.18.549543 — immunology — Posted on 2024-03-18

2157 Primate Saccade Rhythmicity

Näher, T.; Zhang, Y.; Pandinelli, M.; Fries, P.

10.1101/2023.09.27.559710 — neuroscience — Posted on 2024-03-18

2158 A novel nabelschnur protein regulates segregation of the kinetoplast DNA in Trypanosoma brucei

Cadena, L. R.; Hammond, M.; Tesarov, M.; Chmelova, L.; Svobodova, M.; Durante, I. M.; Yurchenko, V.; Lukes, J.

10.1101/2024.03.18.585547 — molecular biology — Posted on 2024-03-18

2159 MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression

Lin, R.; Roeder, R. G.; Barrows, D.; Mo, Y.; Onikubo, T.; Zhang, Z.

10.1101/2024.03.18.585606 — molecular biology — Posted on 2024-03-18

2160 A Protein Language Model for Exploring Viral Fitness Landscapes

Ito, J.; Strange, A.; Liu, W.; Joas, G.; Lytras, S.; The Genotype to Phenotype Japan (G2P-Japan) Consortium, ; Sato, K.

10.1101/2024.03.15.584819 — microbiology — Posted on 2024-03-18

2161 Sustainable and Ecofriendly Nanoparticle Synthesis Using Microbial Strains Isolated From Heavy Metal Rich Industrial Effluent

Nathan, S.; Mathunny, S.; J, A.

10.1101/2024.03.16.585342 — microbiology — Posted on 2024-03-18

2162 The evolutionary and molecular history of a chikungunya virus outbreak lineage

Krambrich, J.; Mihalic, F.; Gaunt, M. W.; Bohlin, J.; Hesson, J.; Lundkvist, A.; de Lamballerie, X.; Li, C.; Shi, W.; Pettersson, J. H.- O.

10.1101/2024.03.15.585156 — microbiology — Posted on 2024-03-18

2163 Fitness Factor Genes Conserved within the Multi-species Core Genome of Gram-negative Enterobacterales Species Contribute to Bacteremia Pathogenesis

Mobley, H. L. T.; Anderson, M. T.; Moricz, B. L.; Severin, G. S.; Holmes, C. L.; Ottosen, E. N.; Eichler, T.; Gupta, S.; Paudel, S.; Sinha, R.; Mason, S.; Himpsl, S. D.; Brown, A. N.; Gaca, M. L.; Kiser, C. M.; Clarke, T. H.; Fouts, D. E.; DiRita, V. J.; Bachman, M. A.

10.1101/2024.03.18.585282 — microbiology — Posted on 2024-03-18

2164 Fecal microbial load is a major determinant of gut microbiome variation and a confounder for disease associations

Nishijima, S.; Stankevic, E.; Aasmets, O.; Schmidt, T. S.; Nagata, N.; Keller, M. I.; Ferretti, P.; Juel, H.; Fullam, A.; Schudoma, C.; Robbani, S. M.; Hansen, J. K.; Holm, L. A.; Israelsen, M.; Schierwagen, R.; Torp, N.; Arumugam, M.; Bendtsen, F.; Broens, C.; Fonvig, C. E.; Holm, J.-C.; Nielsen, T.; Pedersen, J. S.; Thiele, M. S.; Trebicka, J.; Org, E.; Krag, A.; Hansen, T.; Kuhn, M.; Bork, P.

10.1101/2024.03.18.584290 — microbiology — Posted on 2024-03-18

2165 Natural history of eukaryotic DNA viruses with double jelly-roll major capsid proteins

Krupovic, M.; Kuhn, J. H.; Fischer, M.; Koonin, E. V.

10.1101/2024.03.18.585575 — microbiology — Posted on 2024-03-18

2166 Identification of unique and potent inhibitors of SARS-CoV-2 main protease from DNA-encoded chemical libraries

Akaberi, D.; Pourghasemi Lati, M.; Krambrich, J.; Berger, J.; Strandback, E.; Turunen, P.; Gullberg, H.; Moche, M.; Chinthakindi, P. K.; Nyman, T.; Sandstrom, A.; Jarhult, J. D.; Sandberg, K.; Lundkvist, A.; Verho, O.; Lennerstrand, J.

10.1101/2024.03.16.585341 — microbiology — Posted on 2024-03-18

2167 Genome-Wide Transcription Response of Staphylococcus epidermidis to Heat Shock and Medically Relevant Glucose Levels

Benjamin, K. N.; Goyal, A.; Nair, R. V.; Endy, D.

10.1101/2024.03.18.585582 — microbiology — Posted on 2024-03-18

2168 Role of socioeconomic factors and interkingdom crosstalk in the dental plaque microbiome in early childhood caries

Khan, M. W.; de Jesus, V. C.; Mittermuller, B.-A.; Sareen, S.; Lee, V.; Schroth, R. J.; Hu, P.; Chelikani, P.

10.1101/2024.03.12.584708 — microbiology — Posted on 2024-03-18

2169 A widespread family of ribosomal peptide metallophores involved in bacterial adaptation to copper stress

Leprevost, L.; Junger, S.; Lippens, G.; Guillaume, C.; Sicoli, G.; Oliveira Correia, L.; Rivera-Millot, A.; Billon, G.; Henry, C.; Antoine, R.; Dubiley, S.; Zirah, S.; Li, Y.; Jacob-Dubuisson, F.

10.1101/2024.03.18.585515 — microbiology — Posted on 2024-03-18

2170 Modulation of SARS-CoV-2 spike binding to ACE2 throughconformational selection

Saha, P.; Fernanadez, I.; Sumbul, F.; Valotteau, C.; Kostrz, D.; Meola, A.; Baquero, E.; Sharma, A.; Portman, J. R.; Stransky, F.; Boudier, T.; Guardado Calvo, P.; Gosse, C.; Strick, T.; Rey, F. A.; Rico, F.

10.1101/2024.03.15.585207 — biophysics — Posted on 2024-03-18

2171 IDRWalker: A Random Walk based Modeling Tool for Disordered Regions in Proteins

Chen, G.; Zhang, Z.

10.1101/2024.03.17.585378 — bioinformatics — Posted on 2024-03-18

2172 Phage as signatures of healthy microbiomes

Wheatley, R. M.; Holtappels, D.; Koskella, B.

10.1101/2024.03.18.585470 — microbiology — Posted on 2024-03-18

2173 The Candida auris Hog1 MAP kinase is essential for the colonization of murine skin and intradermal persistence

Shivarathri, R.; Chauhan, M.; Datta, A.; Das, D.; Karuli, A.; Jenull, S.; Kuchler, K.; Thangamani, S.; Chowdhary, A.; Desai, J. V.; Chauhan, N.

10.1101/2024.03.18.585572 — microbiology — Posted on 2024-03-18

2174 Structural diversity and clustering of bacterial flagellar outer domains

Fields, J. L.; Zhang, H.; Bellis, N. F.; Petersen, H. A.; Halder, S. K.; Rich-New, S. T.; Wu, H.; Wang, F.

10.1101/2024.03.18.585621 — microbiology — Posted on 2024-03-18

2175 Molecular Characterization of Vaginal Microbiota Using a New 22-Species qRT-PCR Test to Achieve a Relative-abundance and Species-based Diagnosis of Bacterial Vaginosis

Oyenihi, A. B.; Haines, R.; Trama, J.; Faro, S.; Adelson, M. E.; Mordechai, E.; Sekyere, J. O.

10.1101/2024.03.18.585539 — microbiology — Posted on 2024-03-18

2176 Indiscriminate activities of different Henipavirus polymerase complex proteins allow for efficient minigenome replication in hybrid systems

Li, X.; Yang, Y.; Lopez, C. B.

10.1101/2024.03.18.585482 — microbiology — Posted on 2024-03-18

2177 Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin

Liu, T.; Reiser, W. K.; Tan, T. J. C.; Lv, H.; Rivera-Cardona, J.; Heimburger, K.; Wu, N. C.; Brooke, C. B.

10.1101/2024.03.18.585603 — microbiology — Posted on 2024-03-18

2178 Binding of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition

Fahoum, J.; Billan, M.; Varga, J. K.; Padawer, D.; Elgrably-Weiss, M.; Basu, P.; Stolovich-Rain, M.; Baraz, L.; Kumari, S.; Oiknine-Dijan, E.; Kumar, M.; Cohen-Kfir, E.; Zelig, O.; Mayer, G.; Isupov, M. N.; Wolf, D. G.; Altuvia, S.; Wiener, R.; Schueler-Furman, O.; Rouvinski, A.

10.1101/2024.03.17.585388 — immunology — Posted on 2024-03-18

2179 Gene editing of CD3 epsilon gene to redirect regulatory T cells for adoptive T cell transfer

Du, W.; Noyan, F.; McCallion, O.; Drosdek, V.; Kath, J.; Glaser, V.; Fuster-Garcia, C.; Yang, M.; Stein, M.; Weber, O.; Polansky, J. K.; Cathomen, T.; Jaeckel, E.; Hester, J.; Issa, F.; Volk, H.-D.; Schmueck-Henneresse, M.; Reinke, P.; Wagner, D. L.

10.1101/2024.03.18.584896 — immunology — Posted on 2024-03-18

2180 CORACLE (COVID-19 liteRAture CompiLEr): A platform for efficient tracking and extraction of SARS-CoV-2 and COVID-19 literature, with examples from post-COVID with respiratory involvement

Piontkovskaya, K.; Luo, Y.; Lindberg, P.; Gao, J.; Runold, M.; Kolosenko, I.; Li, C.-X.; Wheelock, A. M.

10.1101/2024.03.18.584627 — bioinformatics — Posted on 2024-03-18

2181 Atomically accurate de novo design of single-domain antibodies

Bennett, N. R.; Watson, J. L.; Ragotte, R. J.; Borst, A. J.; See, D. L.; Weidle, C.; Biswas, R.; Shrock, E. L.; Leung, P. J. Y.; Huang, B.; Goreshnik, I.; Ault, R.; Carr, K. D.; Singer, B.; Criswell, C.; Vafeados, D.; Garcia Sanchez, M.; Kim, H. M.; Vazquez Torres, S.; Chan, S.; Baker, D.

10.1101/2024.03.14.585103 — bioengineering — Posted on 2024-03-18

2182 Neural speech tracking in newborns: prenatal learning and contributing factors

Florea, C.; Riemann, M.; Schmidt, F.; Preiss, J.; Reisenberger, E.; Angerer, M.; Ameen, M.; Heib, D. P. J.; Roehm, D.; Schabus, M.

10.1101/2024.03.18.585222 — developmental biology — Posted on 2024-03-18

2183 Anxiety-related attentional changes and their relation to freezing of gait in people with Parkinson's: a cross validation of the Adapted Gait Specific Attentional Profile (G-SAPa)

Rosenblum, U.; Cocks, A. J.; Norris, M.; Kal, E.; Young, W. R.

10.1101/2024.03.14.585018 — neuroscience — Posted on 2024-03-18

2184 Nfib regulates progenitor competence in maturation of GABAergic neurons

Kotlyarenko, Y.; Bright, A. R.; Neuhaus, F.; Rodrigues, D.; Vitali, I.; Myoga, M. H.; Mayer, C.

10.1101/2024.03.18.585524 — neuroscience — Posted on 2024-03-18

2185 Neurodevelopmentally rooted epicenters in schizophrenia: sensorimotor-association spatial axis of cortical thickness alterations

Fan, Y.-S.; Xu, Y.; Hettwer, M. D.; Yang, P.; Sheng, W.; Wang, C.; Yang, M.; Kirschner, M.; Valk, S. L.; Chen, H.

10.1101/2024.03.13.584752 — neuroscience — Posted on 2024-03-18

2186 Unraveling the Time-Frequency Features of Emotional Regulation: Based on an Interpretable XGBoost-SHAP Analytical Framework

Cheng, S.

10.1101/2024.03.15.585273 — neuroscience — Posted on 2024-03-18

2187 Single-cell sequencing of rodent ventral pallidum reveals diverse neuronal subtypes with non-canonical interregional continuity

Ottenheimer, D. J.; Simon, R. C.; Burke, C. T.; Bowen, A. J.; Ferguson, S. M.; Stuber, G. D.

10.1101/2024.03.18.585611 — neuroscience — Posted on 2024-03-18

2188 Consequences of neuronal morphology for spatially precise optogenetic stimulation

Berling, D.; Baroni, L.; Chaffiol, A.; Gauvain, G.; Picaud, S.; Antolik, J.

10.1101/2024.03.18.585466 — neuroscience — Posted on 2024-03-18

2189 In vivo optogenetics using a Utah Optrode Array with enhanced light output and spatial selectivity

McAlinden, N.; Reiche, C. F.; Clark, A.; Scharf, R.; Cheng, Y.; Sharma, R.; Rieth, L.; Dawson, M. D.; Angelucci, A.; Mathieson, K.; Blair, S.

10.1101/2024.03.18.585479 — neuroscience — Posted on 2024-03-18

2190 A brain-to-text framework of decoding natural tonal sentences

Zhang, D.; Wang, Z.; Qian, Y.; Zhao, Z.; Liu, Y.; Hao, X.; Li, W.; Lu, S.; Zhu, H.; Chen, L.; Xu, K.; Li, Y.; Wu, J.; Lu, J.

10.1101/2024.03.16.585337 — neuroscience — Posted on 2024-03-18

2191 Structure and Functions of Gesture Sequences in Wild Bonnet Macaques (Macaca radiata)

Gupta, S.; Sinha, A.

10.1101/2024.03.18.585581 — animal behavior and cognition — Posted on 2024-03-18

2192 Endogenous Precision of the Number Sense

Prat-Carrabin, A.; Woodford, M.

10.1101/2024.03.14.585091 — animal behavior and cognition — Posted on 2024-03-18

2193 Fibroblast diversification is an embryonic process dependent on muscle contraction

coren, L.; Zaffryar-Eilot, S.; Odeh, A.; Kaganovsky, A.; Hasson, P.

10.1101/2024.03.18.585498 — developmental biology — Posted on 2024-03-18

2194 Limb connective tissue is organized in a continuum of promiscuous fibroblast identities during development

HIRSINGER, E.; BLAVET, C.; BONNIN, M.-A.; BELLENGER, L.; GHARSALLI, T.; DUPREZ, D.

10.1101/2024.03.18.585505 — developmental biology — Posted on 2024-03-18

2195 Novel carbon nanoparticles (CNPs) from Catharanthus roseus petals for metal ion sensing and root growth modulation

Omprabha, S.; Kaushal, C.; Gawande, N. D.; Barot, R.; Bhatia, D.; Sankaranarayanan, S.

10.1101/2024.03.18.585564 — developmental biology — Posted on 2024-03-18

2196 Dynamics of Brain Connectivity across the Alzheimer's Disease Spectrum: a magnetoencephalography study

Carrasco-Gomez, M.; Garcia-Colomo, A.; Cabrera-Alvarez, J.; Bruna, R.; Santos, A.; Maestu, F.

10.1101/2024.03.14.584574 — neuroscience — Posted on 2024-03-18

2197 The Origin of Movement Biases During Reaching

Wang, T.; Morehead, R.; Tsay, J. S.; Ivry, R. B.

10.1101/2024.03.15.585272 — neuroscience — Posted on 2024-03-18

2198 Parent attention-orienting behavior is associated with neural entropy in infancy

Williams, C. L.; Belkowitz, A. R.; Nance, M. G.; Mortman, E. T.; Bae, S.; Ahmed, S.-B.; Puglia, M. H.

10.1101/2024.03.14.585061 — neuroscience — Posted on 2024-03-18

2199 Impaired functional brain-heart interplay sustains emotion dysregulation in depressed individuals

Catrambone, V.; Mura, F.; Patron, E.; Gentili, C.; Valenza, G.

10.1101/2024.03.14.585023 — neuroscience — Posted on 2024-03-18

2200 Classification and analysis of retinal interneurons by computational structure under natural scenes

Lee, D.; Kim, J.; Baccus, S. A.

10.1101/2024.03.18.585364 — neuroscience — Posted on 2024-03-18

2201 Dissociable dorsal medial prefrontal cortex ensembles are necessary for cocaine seeking and fear conditioning in mice

Liu, S.; Nawarawong, N.; Liu, X.; Liu, Q.-s.; Olsen, C. M.

10.1101/2024.03.17.585444 — neuroscience — Posted on 2024-03-18

2202 VLK drives extracellular phosphorylation of EphB2 to govern the EphB2-NMDAR interaction and injury-induced pain

Srikanth, K. D.; Elahi, H.; Chander, P.; Washburn, H. R.; Hassler, S.; Mwirigi, J. M.; Kume, M.; Loucks, J.; Arjarapu, R.; Hodge, R.; Shiers, S. I.; Sankaranarayanan, I.; Erdjument-Bromage, H.; Neubert, T. A.; Campbell, Z. T.; Paik, R.; Price, T. J.; Dalva, M. B.

10.1101/2024.03.18.585314 — neuroscience — Posted on 2024-03-18

2203 CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability

Hommersom, M. P.; Doorn, N.; Puvogel, S.; Lewerissa, E. I.; Mordelt, A.; Ciptasari, U.; Kampshoff, F.; Dillen, L.; van Beusekom, E.; Oudakker, A.; Kogo, N.; Frega, M.; Schubert, D.; van de Warrenburg, B. P. C.; Nadif Kasri, N.; van Bokhoven, H.

10.1101/2024.03.18.585506 — neuroscience — Posted on 2024-03-18

2204 Characterising the stimulus-response function of mouse C-low threshold mechanoreceptors to mechanical stimuli in vivo

Semizoglou, E.; Lo-Re, L.; Middleton, S. J.; Perez Sanchez, J.; Tufarelli, T.; Bennett, D. L.; Chisholm, K. I.

10.1101/2024.03.18.585483 — neuroscience — Posted on 2024-03-18

2205 How to measure functional connectivity using resting-state fMRI? A comprehensive empirical exploration of different connectivity metrics

Roell, L.; Wunderlich, S.; Roell, D.; Raabe, F.; Wagner, E.; Shi, Z.; Schmitt, A.; Falkai, P.; Stoecklein, S.; Keeser, D.

10.1101/2024.03.18.585458 — neuroscience — Posted on 2024-03-18

2206 Evaluating a Novel High-Density EEG Sensor Net Structure for Improving Inclusivity in Infants with Curly or Tightly Coiled Hair

Mlandu, N.; McCormick, S. A.; Davel, L.; Zieff, M. R.; Bradford, L.; Herr, D.; Jacobs, C. A.; Khumalo, A.; Knipe, C.; Madi, Z.; Mazubane, T.; Methola, B.; Mhlakwaphalwa, T.; Miles, M.; Goolam Nabi, Z.; Negota, R.; Nkubungu, K.; Pan, T.; Samuels, R.; Williams, S.; Williams, S. R.; Avery, T.; Foster, G.; Donald, K. A.; Gabard-Durnam, L. J.

10.1101/2024.03.18.584988 — neuroscience — Posted on 2024-03-18

2207 Movement quality moderates the effect of spatially congruent cues on the stability of rhythmic bimanual finger movements.

Denyer, R.; Boyd, L. A.

10.1101/2024.03.18.585605 — neuroscience — Posted on 2024-03-18

2208 Diffusion and Oligomerization States of the Muscarinic M1 Receptor in Live Cells - The Impact of Ligands and Membrane Disruptors

Zhou, X.; Septien-Gonzalez, H.; Husaini, S.; Ward, R. J.; Milligan, G.; Gradinaru, C. C.

10.1101/2024.03.18.585390 — biophysics — Posted on 2024-03-18

2209 Twist - torsion coupling in beating axonemes

Striegler, M.; Friedrich, B. M.; Diez, S.; Geyer, V. F.

10.1101/2024.03.18.585533 — biophysics — Posted on 2024-03-18

2210 A general evolution landscape of language and cognition genes

Zhang, Z.; Zhang, S.; Zhou, H.; Xu, Y.

10.1101/2024.03.11.584338 — molecular biology — Posted on 2024-03-18

2211 Genome-Wide Association Study in Outbred Heterogeneous Stock Rats Identifies Multiple Loci for the Incentive Salience of Reward Cues.

King, C. P.; Chitre, A. S.; Leal-Gutierrez, J. D.; Tripi, J. A.; Hughson, A.; Horvath, A.; Lamparelli, A. C.; George, A.; Martin, C.; St. Pierre, C. L.; Bimschleger, H. V.; Gao, J.; Cheng, R.; Nguyen, K.-M.; Holl, K. L.; Polesskaya, O.; Ishiwari, K.; Chen, H.; Solberg-Woods, L. C.; Palmer, A. A.; Robinson, T. E.; Flagel, S. B.; Meyer, P. J.

10.1101/2024.03.13.584852 — neuroscience — Posted on 2024-03-18

2212 Mitochondria drive microglial NRLP3 inflammasome activation via TSPO

Singh, A.; Rigon, M.; Caldeira, M.; Faccenda, D.; Xia, D.; Lopez-Tremoleda, J.; Falah Hassan Al-Khateeb, Z.; Guo, T.; Abeti, R.; Giunti, P.; Campanella, M.

10.1101/2024.03.18.585507 — cell biology — Posted on 2024-03-18

2213 Metastatic site influences driver gene function in pancreatic cancer

Tsanov, K. M.; Barriga, F. M.; Ho, Y.-J.; Alonso-Curbelo, D.; Livshits, G.; Koche, R. P.; Baslan, T.; Simon, J.; Tian, S.; Wuest, A. N.; Luan, W.; Wilkinson, J. E.; Masilionis, I.; Dimitrova, N.; Iacobuzio-Donahue, C. A.; Chaligne, R.; Pe'er, D.; Massague, J.; Lowe, S. W.

10.1101/2024.03.17.585402 — cancer biology — Posted on 2024-03-18

2214 Drosophila melanogaster Set8 and L(3)mbt function in gene expression independently of histone H4 lysine 20 methylation

Crain, A. T.; Butler, M. B.; Hill, C. A.; Huynh, M.; McGinty, R. K.; Duronio, R. J.

10.1101/2024.03.12.584710 — genomics — Posted on 2024-03-18

2215 Chloroplastic ascorbate acts as a regulatory hub in plant metabolism regardless of oxidative stress

Toth, D.; Tengolics, R.; Aarabi, F.; Karlsson, A.; Vidal-Meireles, A.; Kovacs, L.; Kuntam, S.; Kormoczi, T.; Fernie, A. R.; Hudson, E.; Papp, B.; Toth, S. Z.

10.1101/2024.03.14.585081 — plant biology — Posted on 2024-03-18

2216 Biosurfer for systematic tracking of regulatory mechanisms leading to protein isoform diversity

Murali, M.; Saquing, J.; Lu, S.; Gao, Z.; Jordan, B.; Wakefield, Z.; Fiszbein, A.; Cooper, D.; Castaldi, P.; Korkin, D.; Sheynkman, G.

10.1101/2024.03.15.585320 — genomics — Posted on 2024-03-18

2217 Long-read single-cell RNA sequencing enables the study of cancer subclone-specific genotype and phenotype in chronic lymphocytic leukemia

Black, G. S.; Huang, X.; Qiao, Y.; Moos, P.; Sampath, D.; Stephens, D. M.; Woyach, J. A.; Marth, G. T.

10.1101/2024.03.15.585298 — genomics — Posted on 2024-03-18

2218 Highly Pathogenic Avian Influenza A (H5N1) Suspected in penguins and shags on the Antarctic Peninsula and West Antarctic Coast

Leon, F.; Le Bohec, C.; Pizarro, E. J.; Baille, L.; Cristofari, R.; Houstin, A.; Zitterbart, D. P.; Barriga, G.; Poulin, E.; Vianna, J. A.

10.1101/2024.03.16.585360 — genetics — Posted on 2024-03-18

2219 Endosomal sorting protein SNX4 limits synaptic vesicle docking and release

Poppinga, J.; Barret, N. J.; Cornelisse, L. N.; Verhage, M.; van Weering, J. R. T.

10.1101/2024.03.15.584406 — cell biology — Posted on 2024-03-18

2220 Moonlighting on the Fasciola hepatica tegument: enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host

O'Kelly, E.; Cwiklinski, K.; De Marco Verissimo, C.; Calvani, N. E. D.; Lopez Corrales, J.; Jewhurst, H.; Flaus, A.; Lalor, R.; Serrat, J.; Dalton, J. P.; Gonzalez-Miguel, J.

10.1101/2024.03.15.585155 — molecular biology — Posted on 2024-03-18

2221 Isolate-anchored comparisons reveal evolutionary and functional differentiation across SAR86 marine bacteria

Ramfelt, O.; Freel, K. C.; Tucker, S. J.; Nigro, O. D.; Rappe, M. S.

10.1101/2024.03.17.584874 — microbiology — Posted on 2024-03-18

2222 Selective enrichment of Methylococcaceae versus Methylocystaceae methanotrophs via control of methane feeding scheme

Lee, J. Y.; Choi, M.; Song, M. J.; Kim, D. D.; Yun, T.; Chang, J.; Ho, A.; Myung, J.; Yoon, S.

10.1101/2024.03.18.585448 — microbiology — Posted on 2024-03-18

2223 Genetic evidence for a regulated cysteine protease catalytic triad in LegA7, a Legionella pneumophila protein that impinges on a stress response pathway

Hershkovitz, D.; Chen, E. J.; Ensminger, A. W.; Dugan, A. S.; Joyce, A. C.; Segal, G.; Isberg, R. R.

10.1101/2024.03.17.585421 — microbiology — Posted on 2024-03-18

2224 Translation of monosynaptic circuits underlying amygdala fMRI neurofeedback training

Trambaiolli, L. R.; Maffei, C.; Dann, E.; Biazoli, C.; Bezgin, G.; Yendiki, A.; Haber, S.

10.1101/2024.03.15.585281 — neuroscience — Posted on 2024-03-18

2225 Neural dynamics of semantic control underlying generative storytelling

Rastelli, C.; Greco, A.; Finocchiaro, C.; Penazzi, G.; Braun, C.; De Pisapia, N.

10.1101/2024.03.16.584998 — neuroscience — Posted on 2024-03-18

2226 Validation of Enhancer Regions in Primary Human Neural Progenitor Cells using Capture STARR-seq

Gaynor-Gillett, S. C.; Cheng, L.; Shi, M.; Liu, J.; Wang, G.; Spector, M.; Flaherty, M.; Wall, M.; Hwang, A.; Gu, M.; Chen, Z.; Chen, Y.; PsychENCODE Consortium, ; Moran, J. R.; Zhang, J.; Lee, D.; Gerstein, M.; Geschwind, D.; White, K. P.

10.1101/2024.03.14.585066 — neuroscience — Posted on 2024-03-18

2227 Cytokine expression patterns predict suppression of vulnerable neural circuits in a mouse model of Alzheimer's disease

Chan, D. C.; Kim, C.; Kang, R. Y.; Kuhn, M. K.; Beidler, L. M.; Zhang, N.; Proctor, E. A.

10.1101/2024.03.17.585383 — neuroscience — Posted on 2024-03-18

2228 Discovery of active mouse, plant and fungal cytochrome P450s in endogenous proteomes and upon expression in planta.

Font Farre, M.; Brown, D.; Toth, R.; Mahadevan, C.; Brazier-Hicks, M.; Morimoto, K.; Kaschani, F.; Sinclair, J.; Dale, R.; Hall, S.; Morris, M.; Kaiser, M.; Wright, A. T.; Burton, J.; van der Hoorn, R. A. L.

10.1101/2024.03.18.585456 — plant biology — Posted on 2024-03-18

2229 Predicting cell-type-specific exon inclusion in the human brain reveals more complex splicing mechanisms in neurons than glia

Michielsen, L.; Hsu, J.; Joglekar, A.; Belchikov, N.; Reinders, M.; Tilgner, H.; Mahfouz, A.

10.1101/2024.03.18.585465 — bioinformatics — Posted on 2024-03-18

2230 Multi-layered Network Analysis of Osteoking in the Treatment of Osteoporosis: Unraveling Mechanisms from Gene Expression to Molecular Docking

Chen, H.; Ying, J.; Xie, X.; Huang, B.; Lin, P.

10.1101/2024.03.18.585459 — bioinformatics — Posted on 2024-03-18

2231 Accelerating the continuous community sharing of digital neuromorphology data

Tecuatl, C.; Ljungquist, B.; Ascoli, G. A.

10.1101/2024.03.15.585306 — bioinformatics — Posted on 2024-03-18

2232 De novo PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription

Love, L.; Jutte, B. B.; Lindqvist, B.; Thomas, N. A.; Kieri, O.; Nowak, P.; Svensson, J. P.

10.1101/2024.03.17.583304 — microbiology — Posted on 2024-03-18

2233 Mutational analysis of the F plasmid partitioning protein ParA reveals novel residues required for oligomerisation and plasmid maintenance

Mitra, N.; Mishra, D.; Puthethu, I. A.; SRINIVASAN, R.

10.1101/2024.03.17.585406 — microbiology — Posted on 2024-03-18

2234 Tobacco Smoke Exposure is Characterized by a Distinct Nasal Rhinotype in a Pediatric Population

Monaco, H.; Elaiho, C.; Liu, B.; Chan, T.; Cantor, A.; Collaco, J. M.; McGrath-Morrow, S.; Wilson, K.; Clemente, J. C.

10.1101/2024.03.15.585112 — microbiology — Posted on 2024-03-18

2235 Myosin A and F-Actin play a critical role in mitochondrial dynamics and inheritance in Toxoplasma gondii

Souza, R. O. O.; Yang, C.; Arrizabalaga, G.

10.1101/2024.03.18.585462 — microbiology — Posted on 2024-03-18

2236 Cell intrinsic mechanical regulation of plasma membrane accumulation at the cytokinetic furrow

Alonso-Matilla, R.; Lam, A.; Miettinen, T. P.

10.1101/2023.11.13.566882 — cell biology — Posted on 2024-03-18

2237 Genome-wide CRISPRa screens nominate modulators of CAR T cell survival within distinct tumor cytokine milieus

Curtis, B. C.; Spurrell, C. H.; Flint, L.; Lande, A. M.; Leonardi, M.; Rosser, J. M.; Valdez, A.; Murren, N.; Chai, T.; Fitzgerald, M.; Martinez-Reyes, J.; Saxby, C. P.; Oda, S. K.; Jensen, M. C.

10.1101/2024.03.16.583115 — immunology — Posted on 2024-03-18

2238 Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan

Nordin, K.; Pedersen, R.; Falahati, F.; Johansson, J.; Grill, F.; Andersson, M.; Korkki, S. M.; Backman, L.; Zalesky, A.; Rieckmann, A.; Nyberg, L.; Salami, A.

10.1101/2023.03.24.534115 — neuroscience — Posted on 2024-03-18

2239 Large-scale color biases in the retinotopic functional architecture are region specific and shared across human brains

Bannert, M. M.; Bartels, A.

10.1101/2020.05.31.126532 — neuroscience — Posted on 2024-03-18

2240 Single neurons and networks in the claustrum integrate input from widespread cortical sources

Shelton, A. M.; Oliver, D. K.; Lazarte, I. P.; Grimstvedt, J. S.; Kapoor, I.; Swann, J. A.; Ashcroft, C. A.; Williams, S. N.; Conway, N.; Tir, S.; Robinson, A.; Peirson, S. N.; Akam, T.; Kentros, C.; Witter, M. P.; Butt, S. J.; Packer, A. M.

10.1101/2022.05.06.490864 — neuroscience — Posted on 2024-03-18

2241 Reduced avoidance bias to social threat signals in women taking oral contraceptives

Thurley, J.; Buades Rotger, M.; Serfling, G.; Howaldt, T.; Reisch, N.; Kramer, U. M.

10.1101/2023.11.13.566589 — neuroscience — Posted on 2024-03-18

2242 Deconstructing Intratumoral Heterogeneity through Multiomic and Multiscale Analysis of Serial Sections

Schupp, P. G.; Shelton, S. J.; Brody, D. J.; Eliscu, R.; Johnson, B. E.; Mazor, T.; Kelley, K. W.; Potts, M. B.; McDermott, M. W.; Huang, E. J.; Lim, D. A.; Pieper, R. O.; Berger, M. S.; Costello, J. F.; Phillips, J. J.; Oldham, M. C.

10.1101/2023.06.21.545365 — cancer biology — Posted on 2024-03-18

2243 Lack of dominant-negative activity for tumor-associated ZNRF3 missense mutations at endogenous expression levels

Li, S.; Niu, J.; Zhang, R.; Massaar, S.; Merode, J. v.; Schipper, N. d.; Kamp, L. v. d.; Peppelenbosch, M. P.; Smits, R.

10.1101/2024.03.14.585013 — cancer biology — Posted on 2024-03-18

2244 Heterogeneity analysis of acute exacerbations of chronic obstructive pulmonary disease and a deep learning framework with weak supervision and privacy protection

Suzuki, Y.; Hill, A.; Engel, E.; Granchelli, A.; Lockhart, G.; Banaei-Kashani, F.; Bowler, R. P.

10.1101/2023.12.04.570028 — bioinformatics — Posted on 2024-03-18

2245 VirtuousPocketome: A Computational Tool for Screening Protein-ligand Complexes to Identify Similar Binding Sites

Pallante, L.; Cannariato, M.; Androutsos, L.; Zizzi, E. A.; Bompotas, A.; Hada, X.; Grasso, G.; Kalogeras, A.; Mavroudi, S.; Di Benedetto, G.; Theofilatos, K.; Deriu, M. A.

10.1101/2023.12.12.571207 — bioengineering — Posted on 2024-03-18

2246 Human Pannexin 1 Channel is NOT Phosphorylated by Src Tyrosine Kinase at Tyr199 and Tyr309

Ruan, Z.; Du, J.; Lu, W.; Lee, J.; Li, Y.

10.1101/2023.09.10.557063 — biochemistry — Posted on 2024-03-18

2247 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models

Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.; Kuemmerle, T.

10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-18

2248 Boosting the toolbox for live imaging of translation

Bellec, M.; Chen, R.; Dhayni, J.; Trullo, A.; Avinens, D.; Karaki, H.; Mazzarda, F.; Lenden-Hasse, H.; Favard, C.; Lehmann, R.; Bertrand, E.; Lagha, M.; Dufourt, J.

10.1101/2023.02.25.529998 — developmental biology — Posted on 2024-03-18

2249 Empowering future scientists: Exploring How Mentors Guide Students to Write and Publish Scientific Papers

Minocha, T.; Bhagatwala, T.; Mirzoyan, G.; McDowell, G. S.; Fankhauser, S. C.

10.1101/2024.03.15.585231 — scientific communication and education — Posted on 2024-03-18

2250 Delineating the Role of ITGAM in Macrophage Dynamics and Cardiac Modulation during Sepsis-Induced Cardiomyopathy

Wang, Q.; Huang, H.

10.1101/2024.03.08.583788 — genomics — Posted on 2024-03-18

2251 Integrated Analysis Reveals Immunogenic Cell Death in Sepsis-induced Cardiomyopathy

wang, q.; huang, h.

10.1101/2024.03.08.583644 — genomics — Posted on 2024-03-18

2252 The Diversified Astrocyte Developmental Programs are Modulated by Primary Ciliary Signaling

Wang, L.; Guo, Q.; Acharya, S.; Zheng, X.; Huynh, V.; Whitmore, B.; Yimit, A.; Malhotra, M.; Chatterji, S.; Rosin, N.; Labit, E.; Chipak, C.; Gorzo, K.; Haidey, J.; Elliott, D.; Ram, T.; Zhang, Q.; Kuipers, H.; Gordon, G.; Biernaskie, J.; Guo, J.

10.1101/2024.03.17.585433 — neuroscience — Posted on 2024-03-17

2253 A systems-biology approach connects aging mechanisms with Alzheimer's disease pathogenesis

Leventhal, M. J.; Zanella, C. A.; Kang, B.; Peng, J.; Gritsch, D.; Liao, Z.; Bukhari, H.; Wang, T.; Pao, P.-C.; Danquah, S.; Benetatos, J.; Nehme, R.; Farhi, S.; Tsai, L.-H.; Dong, X.; Scherzer, C.; Feany, M. B.; Fraenkel, E.

10.1101/2024.03.17.585262 — systems biology — Posted on 2024-03-17

2254 High resolution mapping of novel non-transgressive hybrid susceptibility in barley exploited by P. teres f. maculata maps to a single pentatricopeptide repeat-containing protein

Clare, S. J.; Alhashel, A. F.; Li, M.; Effertz, K. M.; Poudel, R. S.; Zhang, J.; Brueggeman, R. S.

10.1101/2024.03.17.585425 — plant biology — Posted on 2024-03-17

2255 Glutamine deprivation alters TGF-β signaling in hepatocellular carcinoma

Gelabert, C.; Campisano, S.; Golan, I. C.; Beyene, N. T.; Heldin, C.-H.; Chisari, A. N.; Sancho, P.; Moustakas, A.; Caja, L.

10.1101/2024.03.17.585424 — cancer biology — Posted on 2024-03-17

2256 A deep profile of gene expression across 18 human cancers

Qiu, W.; Dincer, A. B.; Janizek, J.; Celik, S.; Pittet, M.; Naxerova, K.; Lee, S.-I.

10.1101/2024.03.17.585426 — bioinformatics — Posted on 2024-03-17

2257 Evaluating Paraspinal Muscle Response and Compensation via Musculoskeletal Modeling in Spinal Stenosis Surgeries

Jones, R.; Kumaran, Y.; Padgaonkar, A.; Hoffman, B.; Behrens, K.; Elgafy, H.; Tripathi, S.; Goel, V. K.

10.1101/2024.03.17.585440 — bioengineering — Posted on 2024-03-17

2258 CROPseq-multi: a versatile solution for multiplexed perturbation and decoding in pooled CRISPR screens

Walton, R. T.; Qin, Y.; Blainey, P. C.

10.1101/2024.03.17.585235 — genomics — Posted on 2024-03-17

2259 Estimation of spatial demographic maps from polymorphism data using a neural network

Smith, C. C. R.; Patterson, G. C.; Ralph, P. L.; Kern, A. D.

10.1101/2024.03.15.585300 — evolutionary biology — Posted on 2024-03-17

2260 A progeria-associated BAF-1 mutation modulates gene expression and accelerates aging in C. elegans

Romero-Bueno, R.; Fragoso-Luna, A.; Ayuso, C.; Kavsek, A.; Riedel, C. G.; Ward, J. D.; Askjaer, P.

10.1101/2024.03.17.585430 — cell biology — Posted on 2024-03-17

2261 Insight from Wild Yeast Isolates into the Molecular Mechanisms of Lifespan Variation Mediated by Caloric Restriction

McLean, S.; Lee, M.; Liu, W.; Tantray, R.; Gujjala, V. A.; Zhou, X.; Kaeberlein, M.; Kaya, A.

10.1101/2024.03.17.585422 — molecular biology — Posted on 2024-03-17

2262 Viral challenges and adaptations between Central Arctic Ocean and atmosphere

Rahlff, J.; Westmeijer, G.; Weissenbach, J.; Antson, A.; Holmfeldt, K.

10.1101/2024.03.17.584458 — microbiology — Posted on 2024-03-17

2263 Identification and characterization of neoantigen-reactive CD8+ T cells following checkpoint blockade therapy in a pan-cancer setting

Moss, K. H.; Hansen, U. K.; De Lima, V. A. B.; Borch, A.; Marquez, E. S.; Bjerregaard, A.-m.; Oestrup, O.; Bentzen, A. K.; Marquard, A. M.; Kadivar, M.; Svane, I. M.; Lassen, U.; Hadrup, S. R.

10.1101/2024.03.17.585416 — immunology — Posted on 2024-03-17

2264 Dissecting the binding mechanisms of synaptic membrane adhesion complexes using a micropattern based cellular model

Piette, N.; Strale, P.-O.; Lagardere, M.; Saphy, C.; Reissner, C.; Munier, M.; Missler, M.; Chamma, I.; Sainlos, M.; Thoumine, o.; Studer, V.

10.1101/2024.03.17.584836 — neuroscience — Posted on 2024-03-17

2265 Representing the dynamics of natural marmoset vocal behaviors in frontal cortex

Li, J.; Aoi, M. C.; Miller, C.

10.1101/2024.03.17.585423 — neuroscience — Posted on 2024-03-17

2266 ATF4 orchestrates IL-1α-induced senescence in adult neural stem cells

Neumann, S.; Thelin, E. P.; Sankavaram, S. R.; Persson, S.; Fonseca, L.; Moruzzi, N.; Iacobaeus, E.; Bergsland, M.; Popova, E.; Bader, M.; Svensson, M.; Espinosa, A.; Covacu, R.; Brundin, L.

10.1101/2024.03.17.585394 — neuroscience — Posted on 2024-03-17

2267 Naa80 is required for actin N-terminal acetylation and normal hearing in zebrafish

Ree, R.; Lin, S.-J.; Sti Dahl, L. O.; Huang, K.; Petree, C.; Varshney, G. K.; Arnesen, T.

10.1101/2024.03.17.585386 — biochemistry — Posted on 2024-03-17

2268 The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability

McKenna, J. K.; Wu, Y.; Sonkusre, P.; Chari, R.; Lebensohn, A. M.

10.1101/2024.02.02.578552 — genetics — Posted on 2024-03-17

2269 A consensus motif in ASH1 and further transcripts unifies several RNA motifs required for interaction with the She2p/She3p transport machinery and mRNA localization in yeast

Seiler, M.; Niedner, A.; Heber, S.; Feldbruegge, M.; Jansen, R.-P.; Niessing, D.; Zarnack, K.

10.1101/2024.03.10.584336 — cell biology — Posted on 2024-03-17

2270 Causal evidence for increased theta and gamma phase consistency in a parieto-frontal network during the maintenance of visual attention

Bradley, C.; McCann, E.; Nydam, A. S.; Dux, P. E.; Mattingley, J. B.

10.1101/2024.03.17.585395 — neuroscience — Posted on 2024-03-17

2271 Effects of arbuscular mycorrhizal fungi on nitrogen uptake in cotton (Gossypium hirsutum L.) under low-nitrogen conditions

Wang, H.; wang, y.; cheng, X.; He, Y.; shen, z.; zhang, W.; pu, x.

10.1101/2024.03.17.585399 — plant biology — Posted on 2024-03-17

2272 Fluorescence Lifetime Imaging for Quantification of Targeted Drug Delivery in Varying Tumor Microenvironments

Verma, A.; Pandey, V.; Sherry, C.; James, C.; Matteson, K.; Smith, J. T.; Rudkouskaya, A.; Intes, X.; Barroso, M.

10.1101/2024.01.12.575453 — cancer biology — Posted on 2024-03-17

2273 Information-Content-Informed Kendall-tau Correlation: Utilizing Missing Values

Flight, R. M.; Bhatt, P. S.; Moseley, H. N. B.

10.1101/2022.02.24.481854 — bioinformatics — Posted on 2024-03-17

2274 PreMode predicts mode-of-action of missense variants by deep graph representation learning of protein sequence and structural context

Zhong, G.; Zhao, Y.; Zhuang, D.; Chung, W. K.; Shen, Y.

10.1101/2024.02.20.581321 — bioinformatics — Posted on 2024-03-17

2275 Spec2Class: Accurate Prediction of Plant Secondary Metabolite Class using Deep Learning

Poltorak, V.; Shachaf, N.; Aharoni, A.; Zeevi, D.

10.1101/2024.03.17.585408 — biochemistry — Posted on 2024-03-17

2276 A novel inducible von Willebrand Factor Cre Recombinase mouse strain to study microvascular endothelial cell-specific biological processes in vivo.

Yadav, D.; Conner, J.; Wang, Y.; Saunders, T.; Ubogu, E.

10.1101/2023.07.24.550419 — genetics — Posted on 2024-03-17

2277 Tuft cells act as regenerative stem cells in the human intestine

Huang, L.; Bernink, J. H.; Giladi, A.; Krueger, D.; van Son, G. J. F.; Geurts, M. H.; Busslinger, G.; Lin, L.; Zandvliet, M.; Peters, P. J.; Lopez-Iglesias, C.; Buskens, C. J.; Bemelman, W. A.; Begthel, H.; Clevers, H.

10.1101/2024.03.17.585165 — cell biology — Posted on 2024-03-17

2278 Stalling of Transcription by Putative G-quadruplex Sequences and CRISPR-dCas9

Hoque, M. E.; Kabir, M. L.; Shiekh, S.; Balci, H.; Basu, S.

10.1101/2024.03.17.585391 — molecular biology — Posted on 2024-03-17

2279 Suppressive effects of oroxylin A on intracellular proliferation of Toxoplasma gondii via host cell ERK phosphorylation inhibition

Zhang, Z. Z.; Norose, K.; Shinjyo, N.; Lin, X. X.; Suganami, A.; Tamura, Y.; Sakamoto, H.; Hikosaka, K.

10.1101/2024.03.17.585380 — microbiology — Posted on 2024-03-17

2280 Curcumin-mediated NRF2 induction limits inflammatory damage in preclinical models of cystic fibrosis

Leon-Icaza, S. A.; Fretaud, M.; Cornelie, S.; Bureau, C.; Yatime, L.; Floto, A. R.; Renshaw, S.; Herrmann, J.-L.; Langevin, C.; Cougoule, C.; Bernut, A.

10.1101/2024.03.17.585384 — immunology — Posted on 2024-03-17

2281 The Impact of Model Assumptions in Interpreting Cell Kinetic Studies

Yan, A.; Sadreev, I.; Mackerodt, J.; Zhang, Y.; Macallan, D. C.; Busch, R.; Asquith, B.

10.1101/2024.03.17.584905 — immunology — Posted on 2024-03-17

2282 Dynamic role of GlyT1 as glycine sink or source: pharmacological implications for the gain control of NMDA receptors

SUPPLISSON, S.

10.1101/2024.03.17.585409 — neuroscience — Posted on 2024-03-17

2283 Whole-body connectome of a segmented annelid larva

Jekely, G.; Jasek, S.; Guhmann, M.; Bezares-Calderon, L. A.; Williams, E.; Shahidi, R.

10.1101/2024.03.17.585258 — neuroscience — Posted on 2024-03-17

2284 Endopiriform neurons projecting to ventral CA1 are a critical node for recognition memory

Yamawaki, N.; Login, H.; Feld-Jakobsen, S. O.; Molnar, B. M.; Kirkegaard, M. Z.; Moltesen, M.; Okrasa, A.; Radulovic, J.; Tanimura, A.

10.1101/2024.03.17.585387 — neuroscience — Posted on 2024-03-17

2285 Neurosphere culture derived from aged hippocampal dentate gyrus

Vafaeva, O.; Namchaiw, P.; Murray, K. D.; Diaz, E.; Cheng, H.-J.

10.1101/2024.03.16.585365 — neuroscience — Posted on 2024-03-17

2286 Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations

Fernandez, E. C.; Tomassoni, L.; Zhang, X.; Wang, J.; Obradovic, A.; Laise, P.; Griffin, A. T.; Vlahos, L.; Minns, H. E.; Morales, D. V.; Simmons, C.; Gallitto, M.; Wei, H.-J.; Martins, T. J.; Becker, P. S.; Crawford, J. R.; Tzaridis, T.; Wechsler-Reya, R. J.; Garvin, J.; Gartrell, R. D.; Szalontay, L.; Zacharoulis, S.; Wu, C.-C.; Zhang, Z.; Califano, A.; Pavisic, J.

10.1101/2024.03.17.585370 — systems biology — Posted on 2024-03-17

2287 A mathematical model for pancreatic cancer during intraepithelial neoplasia

Briones-Andrade, J.; Ramirez-Santiago, G.; Romero-Arias, J. R.

10.1101/2024.03.16.585362 — cancer biology — Posted on 2024-03-17

2288 High-frequency extracellular spiking in electrically-active cancer cells

Melikov, R.; De Angelis, F.; Moreddu, R.

10.1101/2024.03.16.585162 — bioengineering — Posted on 2024-03-17

2289 D2Sim: A Computational Simulator for NanoporeSequencing based DNA Data Storage

Sankar, s.; Yixin, W.; Noor-A-Rahim, M.; Gunawan, E.; Guan, Y. L.; Poh, C. L.

10.1101/2024.03.17.585393 — bioengineering — Posted on 2024-03-17

2290 Bumblebee visual learning: simple solutions for complex stimuli

Guiraud, M.-G.; Gallo, V.; Quinsal-Keel, E.; MaBouDi, H.

10.1101/2024.03.16.585132 — animal behavior and cognition — Posted on 2024-03-17

2291 Do goldfish like to be informed?

Ajuwon, V.; Monteiro, T.; Walton, M. E.; Kacelnik, A.

10.1101/2024.03.17.585404 — animal behavior and cognition — Posted on 2024-03-17

2292 Large-scale composite hypothesis testing for omics analyses.

De Walsche, A.; Gauthier, F.; Charcosset, A.; Mary-Huard, T.

10.1101/2024.03.17.585412 — genomics — Posted on 2024-03-17

2293 Functional associations of evolutionarily recent human genes exhibit sensitivity to the 3D genome landscape and disease

Fleck, K.; Luria, V.; Garag, N.; Karger, A.; Hunter, T.; Marten, D.; Phu, W.; Nam, K.-M.; Sestan, N.; O'Donnell-Luria, A. H.; Erceg, J.

10.1101/2024.03.17.585403 — evolutionary biology — Posted on 2024-03-17

2294 Retinoic acid, an essential component of the RP organizer, promotes the spatio-temporal segregation of dorsal neural fates

Rekler, D.; Ofek, S.; Kagan, S.; Friedlander, G.; Kalcheim, C.

10.1101/2024.03.17.585392 — developmental biology — Posted on 2024-03-17

2295 Multi-omics discovery of hallmark protein and lipid features of circulating small extracellular vesicles in humans

Rai, A.; Huynh, K.; Poh, Q. H.; Fang, H.; Claridge, B.; Cross, J.; Duong, T.; Duarte, C.; Marwick, T.; Meikle, P.; Greening, D. W.

10.1101/2024.03.16.585131 — cell biology — Posted on 2024-03-17

2296 Protective function of ex vivo expanded CD8 T cells in a mouse model of adoptive therapy for cytomegalovirus infection depends on integrin beta 1 but not CXCR3, CTLA4, or PD-1 expression

Liu, X.; Gutierrez Jauregui, R.; Lueder, Y.; Halle, S.; Ospina-Quintero, L.; Ritter, C.; Schimrock, A.; Willenzon, S.; Janssen, A.; Wagner, K.; Messerle, M.; Bosnjak, B.; Foerster, R.

10.1101/2024.03.16.585350 — immunology — Posted on 2024-03-17

2297 The Area Law of Molecular Entropy: Moving Beyond Harmonic Approximation.

Roy, A.; Venkatraman, V.; Ali, T.

10.1101/2024.03.16.585357 — biophysics — Posted on 2024-03-17

2298 Biomimetic fractal topography enhances podocyte maturation in vitro

Liu, C.; Aggarwal, P.; Wagner, K. T.; Landau, S. S.; Cui, T.; Song, X.; Shamaei, L.; Rafatian, N.; Zhao, Y.; Rodriguez-Ramirez, S.; Morton, K.; Virlee, E.; Li, C. Y.; Bannerman, D.; Pascual-Gil, S.; Okhovatian, S.; Radisic, A.; Clotet-Freixas, S.; Veres, T.; Sadrzadeh, M.; Filleter, T.; Broeckel, U.; Konvalinka, A.; Radisic, M.

10.1101/2024.03.16.585039 — bioengineering — Posted on 2024-03-17

2299 IMMUNOPHENOTYPING AND FUNCTIONAL ANALYSIS OF NK CELL SUBSETS IN Mycobacterium tuberculosis-INFECTED INDIVIDUALS

Silva, C. S.; Folkesson, E.; Foroogh, F.; Gower, M. S.; Kleberg, L.; Xi, P.; Sarhan, D.; Bruchfeld, J.; Correia-Neves, M.; Källenius, G.; Sundling, C.

10.1101/2024.03.16.585339 — immunology — Posted on 2024-03-17

2300 Genome-wide CRISPRa screens nominate modulators of CAR T cell survival within distinct tumor cytokine milieus

Curtis, B. C.; Spurrell, C. H.; Flint, L.; Lande, A. M.; Leonardi, M.; Rosser, J. M.; Valdez, A.; Murren, N.; Chai, T.; Fitzgerald, M.; Martinez-Reyes, J.; Saxby, C. P.; Oda, S. K.; Jensen, M. C.

10.1101/2024.03.16.583115 — immunology — Posted on 2024-03-17

2301 Spectral waveform analysis dissociates human cortical alpha rhythms

Giehl, J.; Siegel, M.

10.1101/2024.03.16.585296 — neuroscience — Posted on 2024-03-17

2302 An arrayed CRISPR/Cas9 screen identifies mTORC1 as a regulator of lipid droplet accumulation in APOE E3 and APOE KO iPSC-derived microglia

Meier, S.; Larsen, A. S. G.; Wanke, F.; Mercado, N.; Mei, A.; Takacs, L.; Mracsko, E. S.; Collin, L.; Kampmann, M.; Roudnicky, F.; Jagasia, R.

10.1101/2024.03.16.585330 — neuroscience — Posted on 2024-03-17

2303 Neurodevelopmental Subtypes of Functional Brain Organization in the ABCD Study Using a Rigorous Analytic Framework

DeRosa, J.; Friedman, N. P.; Calhoun, V.; Banich, M. T.

10.1101/2024.03.16.585343 — neuroscience — Posted on 2024-03-17

2304 Naturalistic Object Representations Depend on Distance and Size Cues

Fairchild, G. T.; Holler, D. E.; Fabbri, S.; Gomez, M. A.; Walsh-Snow, J. C.

10.1101/2024.03.16.585308 — neuroscience — Posted on 2024-03-17

2305 The distribution of particulate organic matter in the heterogeneous soil matrix - balancing between aerobic respiration and denitrification

Lucas, M.; Rohe, L.; Apelt, B.; Stange, C. F.; Vogel, H.-J.; Well, R.; Schlüter, S.

10.1101/2024.03.16.585355 — plant biology — Posted on 2024-03-17

2306 Human circulatory system response to changes in alveolar pressure and lung volume

Semenov, Y. S.; Dyachenko, A. I.; Melnikov, I. S.; Zaripov, R. N.

10.1101/2024.03.16.585354 — physiology — Posted on 2024-03-17

2307 Diclofenac-eugenol modulation of Kv7 and TRPV1 ion channels

Rivera-Ruedas, A.; Medina-Vilchis, A. R.; Romero-Tovar, J. J.; Cristobal-Mondragon, G. R.; De la Rosa, V.

10.1101/2024.03.16.585319 — physiology — Posted on 2024-03-17

2308 Conditions for the co-existence of promoter and gene-body condensates

Changiarath, A.; Michels, J.; Rodriguez, R. H.; Hanson, S. M.; Schmid, F.; Padeken, J.; Stelzl, L. S.

10.1101/2024.03.16.585180 — biophysics — Posted on 2024-03-17

2309 The growth-driven penetration strategy of plant roots is mechanically more efficient than pushing

Koren, Y.; Perilli, A.; Tchaicheeyan, O.; Lesman, A.; Meroz, Y.

10.1101/2024.03.16.585213 — biophysics — Posted on 2024-03-17

2310 LIPIDS MODULATE THE DYNAMICS OF GPCR:β-ARRESTIN INTERACTION

GOMES, A. A. S.; DI MICHELE, M.; ROESSNER, R. A.; DAMIAN, M.; BISCH, P. M.; SIBILLE, N.; LOUET, M.; BANERES, J.-L.; FLOQUET, N.

10.1101/2024.03.16.585329 — biophysics — Posted on 2024-03-17

2311 Evaluation of methods for RNA-Seq analysis for uncovering key components of estrogen receptor-alpha signaling pathway in breast cancer

Guo, W.

10.1101/2024.03.16.585375 — bioinformatics — Posted on 2024-03-17

2312 ERNIE-RNA: An RNA Language Model with Structure-enhanced Representations

Yin, W.; Zhang, Z.; He, L.; Jiang, R.; Zhang, S.; Liu, G.; Zhang, X.; Qin, T.; Xie, Z.

10.1101/2024.03.17.585376 — bioinformatics — Posted on 2024-03-17

2313 Identification of novel prognostic targets in acute kidney injury using bioinformatics and next generation sequencing data analysis

Vastrad, B. M.; Vastrad, C. M.

10.1101/2024.03.17.585400 — bioinformatics — Posted on 2024-03-17

2314 Photoelectricity generation from beet juice in a bio-electrochemical cell

Shlosberg, Y.

10.1101/2024.03.16.585328 — bioengineering — Posted on 2024-03-17

2315 Map of epigenetic age acceleration: a worldwide meta-analysis

Yusipov, I.; Kalyakulina, A.; Franceschi, C.; Ivanchenko, M.

10.1101/2024.03.17.585398 — genetics — Posted on 2024-03-17

2316 Unraveling the Evolutionary Trajectory of LHCI in Red-Lineage Algae: Conservation, Diversification, and Neolocalization

Kumazawa, M.; Ifuku, K.

10.1101/2024.03.16.585336 — evolutionary biology — Posted on 2024-03-17

2317 See-Star: a versatile hydrogel-based protocol for clearing large, opaque and calcified marine invertebrates

Clarke, D. N.; Formery, L.; Lowe, C. J.

10.1101/2024.03.16.585344 — developmental biology — Posted on 2024-03-17

2318 Cell culture differentiation and proliferation conditions influence the in vitro regeneration of the human airway epithelium

Redman, E.; Fierville, M.; Cavard, A.; Plaisant, M.; Arguel, M.-J.; Ruiz Garcia, S.; McAndrew, E. M.; Girard-Riboulleau, C.; Lebrigand, K.; Magnone, V.; Ponzio, G.; Gras, D.; Chanez, P.; Abelanet, S.; Barbry, P.; Marcet, B.; Zaragosi, L.-E.

10.1101/2024.03.16.584842 — cell biology — Posted on 2024-03-17

2319 Internal monitoring of whisking and locomotion in the superior colliculus

Chinta, S.; Pluta, S.

10.1101/2024.03.16.585346 — neuroscience — Posted on 2024-03-17

2320 Deep learning based genomic breeding of pest-resistant grapevine

Gan, Y.; Liu, Z.; Zhang, F.; Xu, Q.; Wang, X.; Xue, H.; Su, X.; Ma, W.; Long, Q.; Ma, A.; Huang, G.; Liu, W.; Xu, X.; Sun, L.; Zhang, Y.; Liu, Y.; Fang, X.; Li, C.; Yang, X.; Wei, P.; Fan, X.; Zhang, C.; Zhang, P.; Liu, C.; Zhang, Z.; Huang, S.; Wang, Y.; Liu, Z.; Zhou, Y.

10.1101/2024.03.16.585323 — plant biology — Posted on 2024-03-17

2321 Quantification of healthspan in aging mice: Introducing FAMY and GRAIL

Lamming, D. W.

10.1101/2023.11.07.566044 — physiology — Posted on 2024-03-17

2322 Evaluation of Gene Set Enrichment Analysis (GSEA) tools highlights the value of single sample approaches over pairwise for robust biological discovery.

Bull, C.; Byrne, R. M.; Fisher, N. C.; Corry, S. M.; Amirkhah, R.; Edwards, J.; Hillson, L.; Lawler, M.; Ryan, A.; Lamrock, F.; Dunne, P. D.; Malla, S. B.

10.1101/2024.03.15.585228 — cancer biology — Posted on 2024-03-17

2323 HIV integrase compacts viral DNA into biphasic condensates

Kolbeck, P. J.; de Jager, M.; Gallano, M.; Brouns, T.; Bekaert, B.; Frederickx, W.; Konrad, S. F.; Van Belle, S.; Christ, F.; De Feyter, S.; Debyser, Z.; Filion, L. C.; Lipfert, J.; Vanderlinden, W.

10.1101/2024.03.15.585256 — biophysics — Posted on 2024-03-17

2324 Characterising tandem repeat complexities across long-read sequencing platforms with TREAT

Tesi, N.; Salazar, A.; Zhang, Y.; van der Lee, S.; Hulsman, M.; Knoop, L.; Wijesekera, S.; Krizova, J.; Schneider, A.-F.; Pennings, M.; Sleegers, K.; Kamsteeg, E.-J.; Reinders, M.; Holstege, H.

10.1101/2024.03.15.585288 — bioinformatics — Posted on 2024-03-17

2325 A Functional Map of the Human Intrinsically Disordered Proteome

Pritisanac, I.; Alderson, T. R.; Kolaric, Đesika; Zarin, T.; Xie, S.; Lu, A. X.; Alam, A.; Maqsood, A.; Youn, J.-Y.; Forman-Kay, J. D.; Moses, A. M.

10.1101/2024.03.15.585291 — bioinformatics — Posted on 2024-03-17

2326 Multiscale Correlations between Joint and Tissue-Specific Biomechanics and Anatomy in Postmortem Ovine Stifles

Chatterjee, A.; Davis, Z. R.; Lescun, T.; Chan, D. D.

10.1101/2024.03.15.585312 — bioengineering — Posted on 2024-03-17

2327 EPA induces an anti-inflammatory transcriptomic landscape in T cells implicating a pathway independent of triglyceride lowering in CVD risk reduction

Reilly, N. A.; Dekkers, K.; Molenaar, J.; Arumugam, S.; Kuipers, T. B.; Ariyurek, Y.; Hoeksema, M. A.; Jukema, J. W.; Heijmans, B. T.

10.1101/2024.03.15.585315 — genomics — Posted on 2024-03-17

2328 Neuronal CBP-1 is required for enhanced body muscle proteostasis in response to reduced translation downstream of mTOR

Snow, S.; Mir, D.; Ma, Z.; Horrocks, J.; Cox, M.; Ruzga, M.; Sayed, H.; Rogers, A. N.

10.1101/2024.03.15.585263 — genetics — Posted on 2024-03-17

2329 Imprinting and DNA methylation in water lily endosperm: implications for seed evolution

Povilus, R. A.; Martin, C. A.; Gehring, M.

10.1101/2024.03.15.585284 — evolutionary biology — Posted on 2024-03-17

2330 Dendritic Cell - Fibroblast Crosstalk via TLR9 and AHR Signaling Drives Lung Fibrogenesis

Carter, H.; Medina Costa, R.; Bame, M.; Gilchrist, T.; Emch, C.; Adams, T.; Linderholm, A.; Oldham, J. M.; Noth, I.; Kaminski, N.; Moore, B. B.; Gurczynski, S. J.

10.1101/2024.03.15.584457 — immunology — Posted on 2024-03-17

2331 CD39 is expressed on functional effector and tissue resident memory CD8+ T cells

Isaacs, J. F.; Degefu, H. N.; Chen, T.; Kleist, S. A.; Musial, S. C.; Ford, M. A.; Searles, T. G.; Lin, C.-C.; Skorput, A. G. J.; Shirai, K.; Turk, M. J.; Zanazzi, G. J.; Rosato, P.

10.1101/2024.03.15.585252 — immunology — Posted on 2024-03-17

2332 Putaminal dopamine modulates movement motivation in Parkinson's disease

Banwinkler, M.; Dzialas, V.; Rigoux, L.; Asendorf, A.; Theis, H.; Giehl, K.; Tittgemeyer, M.; Hoenig, M.; van Eimeren, T.

10.1101/2024.03.15.585221 — neuroscience — Posted on 2024-03-17

2333 FABEL: Forecasting Animal Behavioral Events with Deep Learning-Based Computer Vision

Catto, A.; O'Connor, R.; Braunscheidel, K. M.; Kenny, P. J.; Shen, L.

10.1101/2024.03.15.584610 — neuroscience — Posted on 2024-03-17

2334 Synchrony between midbrain gene transcription and dopamine terminal regulation is modulated by chronic alcohol drinking

Farahbakhsh, Z. Z.; Holleran, K. M.; Sens, J. P.; Fordahl, S. C.; Mauterer, M. I.; Lopez, A. J.; Cuzon Carlson, V. C.; Kiraly, D. D.; Grant, K. A.; Jones, S. R.; Siciliano, C. A.

10.1101/2024.03.15.584711 — neuroscience — Posted on 2024-03-17

2335 Cholinergic Transmission in an Inducible Transgenic Mouse Model of Paroxysmal Dystonia

Scarduzio, M.; Jaunarajs, K.; Standaert, D. G.

10.1101/2024.03.15.585266 — neuroscience — Posted on 2024-03-17

2336 Selectivity and evolution of Aqp10 in solute permeability influenced by pore molecular weight

Nagashima, A.; Ushio, K.; Nishihara, H.; Akimoto, J.; Kato, A.; Furuta, T.

10.1101/2024.03.16.584933 — physiology — Posted on 2024-03-17

2337 Mapping the breast tumor microenvironment: proximity analysis reveals spatial relationships between macrophage subtypes and metastasis-initiating cancer cells

Grasset, E. M.; Desphande, A.; Lee, J. W.; Cho, Y.; Shin, S. M.; Coyne, E. M.; Hernandez, A.; Yuan, X.; Cimino-Matthews, A.; Ewald, A. J.; Ho, W. J.

10.1101/2024.03.15.585195 — cancer biology — Posted on 2024-03-17

2338 Heterotypic Seeding Generates Mixed Amyloid Polymorphs

Banerjee, S.; Baghel, D.; Edmonds, H. O.; Ghosh, A.

10.1101/2024.03.15.585264 — biophysics — Posted on 2024-03-17

2339 Live imaging of Alu elements reveals non-uniform euchromatin dynamics coupled to transcription

Chang, Y.-C.; Quinodoz, S. A.; Brangwynne, C. P.

10.1101/2024.03.15.585287 — biophysics — Posted on 2024-03-17

2340 A {lambda}-dynamics investigation of insulin Wakayama and other A3 variant binding affinities to the insulin receptor

Barron, M. P.; Vilseck, J. Z.

10.1101/2024.03.15.585233 — biophysics — Posted on 2024-03-17

2341 DrugHIVE: Target-specific spatial drug design and optimization with a hierarchical generative model

Weller, J. A.; Rohs, R.

10.1101/2023.12.22.573155 — bioinformatics — Posted on 2024-03-17

2342 Gapless assembly of complete human and plant chromosomes using only nanopore sequencing

10.1101/2024.03.15.585294 — bioinformatics — Posted on 2024-03-17

2343 Conformal prediction of molecule-induced cancer cell growth inhibition challenged by strong distribution shifts

Hernandez-Hernandez, S.; Guo, Q.; Ballester, P.

10.1101/2024.03.15.585269 — bioinformatics — Posted on 2024-03-17

2344 GGTyper: genotyping complex structural variants using short-read sequencing data

Mirus, T.; Lohmayer, R.; Halldorsson, B. V.; Kehr, B.

10.1101/2024.03.15.585230 — bioinformatics — Posted on 2024-03-17

2345 PPIscreenML: Structure-based screening for protein-protein interactions using AlphaFold

Mischley, V.; Maier, J.; Chen, J.; Karanicolas, J.

10.1101/2024.03.16.585347 — bioinformatics — Posted on 2024-03-17

2346 Seasonal variation of behavioural thermoregulation in the Spotted Salamander (Ambystoma maculatum)

Giacometti, D.; Tattersall, G. J.

10.1101/2024.03.15.585242 — animal behavior and cognition — Posted on 2024-03-17

2347 Interpretable and predictive models to harness the life science data revolution

Jahner, J. P.; Buerkle, C. A.; Gannon, D. G.; Grames, E. M.; McFarlane, S. E.; Siefert, A.; Bell, K. L.; DeLeo, V. L.; Forister, M. L.; Harrison, J. G.; Laughlin, D. C.; Patterson, A. C.; Powers, B. F.; Werner, C. M.; Oleksy, I. A.

10.1101/2024.03.15.585297 — genomics — Posted on 2024-03-17

2348 Functional phases encode the response of the soil microbiome to environmental change

Lee, K. K.; Liu, S.; Crocker, K.; Huggins, D. R.; Tikhonov, M.; Mani, M.; Kuehn, S.

10.1101/2024.03.15.584851 — ecology — Posted on 2024-03-17

2349 Growth parameters of the clupeids Limnothrissa miodon and Stolothrissa tanganicae in northern Lake Tanganyika (Bujumbura sub-basin)

N'Sibula, M. T.; Gordo-Vilaseca, C.; Milec, L. J. M.; Patel, D. M.; Busanga, A. K.; Micha, J.-C.; Sarvala, J.; Raeymaekers, J. A. M.

10.1101/2024.03.16.584994 — ecology — Posted on 2024-03-17

2350 N-acetyltransferase 10-mediated mRNA N4-acetylation is Essential for the Translational Regulation During Oocyte Meiotic Maturation in Mice

Chen, L.; Liu, S.-Y.; Su, R.-B.; Wu, Y.-K.; Wang, W.-J.; Wu, X.; Zhang, S.-Y.; Qiao, J.; Sha, Q.-Q.; Fan, H.-Y.

10.1101/2024.03.15.585321 — developmental biology — Posted on 2024-03-17

2351 Nuclear compression-mediated DNA damage drives ATR-dependent Lamin expression and mouse ESC differentiation

Roy, T.; Piplani, N.; Sthanam, L. K.; Ghosh, S.; Tiwary, N.; Dhar, S.; Konyak, W. C. W.; Panigrahi, S. S.; Singh, P.; Sowpati, D. T.; Nair, S.; Kumar, S.; Shekar, P. C.; Sen, S.

10.1101/2024.03.15.585216 — cell biology — Posted on 2024-03-17

2352 The dynamin-related protein Dyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum

Morano, A. A.; Xu, W.; Shadija, N.; Dvorin, J. D.; Ke, H.

10.1101/2024.03.15.585229 — microbiology — Posted on 2024-03-17

2353 Anti-Immune Complex Antibodies are Elicited During Repeated Immunization with HIV Env Immunogens

Brown, S.; Antanasijevic, A.; Sewall, L. M.; Montiel Garcia, D.; Brouwer, P. J. M.; Sanders, R. W.; Ward, A. B.

10.1101/2024.03.15.585257 — immunology — Posted on 2024-03-17

2354 Optimized CART Cell Therapy for Metastatic Aggressive Thyroid Cancer

Gleba, J. J.; Siegler, E. L.; Manriquez-Roman, C.; Huynh, T. N.; Mai, L. K.; Miller, J. L.; Miller, E. E.; Pawlush, M. L.; Alasonyalilar Demirer, A.; Kimball, B. L.; Tapper, E. E.; Sakemura, R. L.; Stewart, C. M.; Can, I.; Sirpilla, O. L.; Feigin, J. M.; Yun, K.; Gutierrez-Ruiz, O. L.; Xia, H.; Hefazi, M.; Schick, K. J.; Ogbodo, E. J.; Olivier, G.; Qiu, Y.; Tun, H. W.; Smallridge, R. C.; Zubair, A.; Copland, J. A.; Kenderian, S. S.

10.1101/2024.03.15.585286 — immunology — Posted on 2024-03-17

2355 A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies

Voitiuk, K.; Seiler, S. T.; Pessoa de Melo, M.; Geng, J.; Hernandez, S.; Schweiger, H. E.; Sevetson, J. L.; Parks, D. F.; Robbins, A.; Torres-Montoya, S.; Ehrlich, D.; Elliott, M. A. T.; Sharf, T.; Haussler, D.; Mostajo-Radji, M. A.; Salama, S. R.; Teodorescu, M.

10.1101/2024.03.15.585237 — neuroscience — Posted on 2024-03-17

2356 Efficiency and reliability in biological neural network architectures

Egas Santander, D.; Pokorny, C.; Ecker, A.; Lazovskis, J.; Santoro, M.; Smith, J. P.; Hess, K.; Levi, R.; Reimann, M. W.

10.1101/2024.03.15.585196 — neuroscience — Posted on 2024-03-17

2357 Lesion-remote astrocytes govern microglia-mediated white matter repair

McCallum, S.; Suresh, k. B.; Islam, T.; Saustad, A. W.; Shelest, O.; Patil, A.; Lee, D. D.; Kwon, B.; Yenokian, I.; Kawaguchi, R.; Beveridge, C. H.; Manchanda, P.; Randolph, C. E.; Meares, G. P.; Plummer, J. T.; Dutta, R.; Knott, S. R.; Chopra, G.; Burda, J. E.

10.1101/2024.03.15.585251 — neuroscience — Posted on 2024-03-17

2358 Widespread innervation of motoneurons by spinal V3 neurons globally amplifies locomotor output in mice.

Zhang, H.; Deska-Gauthier, D.; Mackay, C. S.; Hari, K.; Lucas-Osma, A. M.; Borowska-Fielding, J.; Letawsky, R. L.; Akay, T.; Fenrich, K. K.; Bennett, D. J.; Zhang, Y.

10.1101/2024.03.15.585199 — neuroscience — Posted on 2024-03-17

2359 Spatial contextual information modulates affordance processing and early electrophysiological markers of scene perception

Naveilhan, C.; Saulay-Carret, M.; Zory, R.; Ramanoel, S.

10.1101/2024.03.15.585247 — neuroscience — Posted on 2024-03-17

2360 Transcriptional modulation unique to vulnerable motor neurons predict ALS across species and SOD gene mutations

Mei, I.; Nichterwitz, S.; Leboeuf, M.; Nijssen, J.; Lenoel, I.; Repsilber, D.; Lobsiger, C. S.; Hedlund, E.

10.1101/2024.03.15.584775 — neuroscience — Posted on 2024-03-17

2361 Social state gates vision using three circuit mechanisms in Drosophila

Schretter, C. E.; Hindmarsh Sten, T.; Klapoetke, N.; Shao, M.; Nern, A.; Dreher, M.; Bushey, D.; Robie, A. A.; Taylor, A. L.; Branson, K. M.; Otopalik, A.; Ruta, V.; Rubin, G. M.

10.1101/2024.03.15.585289 — neuroscience — Posted on 2024-03-17

2362 Atypical retinal function in a mouse model of Fragile X syndrome

Vlasits, A. L.; Syeda, M.; Wickman, A.; Guzman, P.; Schmidt, T. M.

10.1101/2024.03.15.585283 — neuroscience — Posted on 2024-03-17

2363 In-gel protein digestion using acidic methanol produces a highly selective methylation of glutamic 1 acid residues.

Lozano-Prieto, M.; Camafeita, E.; Jorge, I.; Laguillo-Gomez, A.; Barrero-Rodriguez, R.; Devesa, C. A.; Pertusa, C.; Calvo, E.; Sanchez-Madrid, F.; Vazquez, J.; Martin-Cofreces, N. B.

10.1101/2024.03.15.585290 — systems biology — Posted on 2024-03-17

2364 Hairpin-RNA Spray Confers Resistance to Mungbean Yellow Mosaic India Virus in Mungbean

Dhobale, K. V.; Sahoo, L.

10.1101/2024.03.15.585278 — plant biology — Posted on 2024-03-17

2365 Transcriptomic analyses in the gametophyte ofDryopteris affinis: apomixis and more

Ojosnegros, S.; Alvarez, J. M.; Gagliardini, V.; Quintanilla, L. G.; Grossniklaus, U.; Fernandez, H.

10.1101/2024.03.15.585305 — plant biology — Posted on 2024-03-17

2366 A matter of food and substrain: obesogenic diets induce differential severity of cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N substrains

Cascarano, L.; Esfahani, H.; Michel, P.; Bouzin, C.; Dessy, C.; Balligand, J.-L.; Michel, L. Y. M.

10.1101/2024.03.15.584713 — physiology — Posted on 2024-03-17

2367 Visualization of endogenous G proteins on endosomes and other organelles

Jang, W.; Senarath, K.; Lu, S.; Lambert, N. A.

10.1101/2024.03.05.583500 — pharmacology and toxicology — Posted on 2024-03-17

2368 Heterogeneous and Novel Transcript Expression in Single Cells of Patient-Derived ccRCC Organoids

Karakulak, T.; Bolck, H. A.; Zajac, N.; Bratus-Neuenschwander, A.; Zhang, Q.; Qi, W.; Oltra, T. C.; Rehrauer, H.; von Mering, C.; Moch, H.; Kahraman, A.

10.1101/2024.03.15.585271 — cancer biology — Posted on 2024-03-17

2369 Random forest machine learning algorithm classifies white- and brown-rot fungi according to the number of Carbohydrate-Active enZyme genes

Hasegawa, N.; Sugiyama, M.; Igarashi, K.

10.1101/2024.03.15.585254 — bioinformatics — Posted on 2024-03-17

2370 CLigOpt: Controllable Ligand Design through Target-Specific Optimisation

Li, Y.; da Costa Avelar, P. H.; Chen, X.; Zhang, L.; Wu, M.; Tsoka, S.

10.1101/2024.03.15.585255 — bioinformatics — Posted on 2024-03-17

2371 Comprehensive machine learning boosts structure-based virtual screening for PARP1 inhibitors

Caba, K.; Tran-Nguyen, V.-K.; Rahman, T.; Ballester, P.

10.1101/2024.03.15.585277 — bioinformatics — Posted on 2024-03-17

2372 Biophysics-based protein language models for protein engineering

Gelman, S.; Johnson, B.; Freschlin, C.; D'Costa, S.; Gitter, A.; Romero, P. A.

10.1101/2024.03.15.585128 — bioinformatics — Posted on 2024-03-17

2373 Celldetective: an AI-enhanced image analysis toolfor unraveling dynamic cell interactions

Torro, R.; Diaz Bello, B.; El Arawi, D.; Ammer, L.; Chames, P.; Sengupta, K.; Limozin, L.

10.1101/2024.03.15.585250 — bioinformatics — Posted on 2024-03-17

2374 A Comparison of Antibody-Antigen Complex Sequence-to-Structure Prediction Methods and their Systematic Biases

McCoy, K. M.; Ackerman, M. E.; Grigoryan, G.

10.1101/2024.03.15.585121 — bioinformatics — Posted on 2024-03-17

2375 MAGNETICALLY-DRIVEN HYDROGEL SURFACES FOR DYNAMIC STIFFNESS MODULATION FOR MODULATING MACROPHAGE BEHAVIOR

Li, L.; Alsema, E.; Beijer, N.; Gumuscu, B.

10.1101/2024.03.15.585191 — bioengineering — Posted on 2024-03-17

2376 Multi-Scale Computational Model of Microvascular Remodeling in Idiopathic Pulmonary Fibrosis

Leonard-Duke, J.; Agro, S. M. J.; Csordas, D. J.; Bruce, A. C.; Eggertsen, T. G.; Tavakol, T. N.; Barker, T. H.; Bonham, C. A.; Saucerman, J. J.; Taite, L. J.; Peirce, S. M.

10.1101/2024.03.15.585249 — bioengineering — Posted on 2024-03-17

2377 Systematic Analysis of Biological Processes Reveals Gene Co-expression Modules Driving Pathway Dysregulation in Alzheimer's Disease

Adeoye, T. O.; Shah, S. I.; Ullah, G.

10.1101/2024.03.15.585267 — genomics — Posted on 2024-03-17

2378 Identification of novel genes in cattle (Bos taurus) and biological insights into their function in embryo development

Schettini, G. P.; Morozyuk, M.; Biase, F. H.

10.1101/2024.03.15.585311 — genomics — Posted on 2024-03-17

2379 Variability and correlations among vital rates and their influence on population growth in mule and black-tailed deer

Ruprecht, J. S.; Forrester, T.; Clark, D.; Wisdom, M.; Smith, J.; Levi, T.

10.1101/2024.03.15.585316 — ecology — Posted on 2024-03-17

2380 Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease

Lichner, Z.; Ding, M.; Khare, T.; Dan, Q.; Benitez, R.; Praszner, M.; Song, X.; Saleeb, R.; Hinz, B.; Pei, Y.; Szaszi, K.; Kapus, A.

10.1101/2024.03.15.585204 — cell biology — Posted on 2024-03-17

2381 Wee1 inhibition decouples Cdk1 and Plk1 activities: a role for gradual Cdk1 activation throughout G2 phase.

Akopyan, K.; Lindqvist, A.

10.1101/2024.03.15.585186 — cell biology — Posted on 2024-03-17

2382 Caskin2 is a novel talin and Abi1-binding protein that promotes cell motility

Wang, W.; Atherton, P.; Kreft, M.; te Molder, L.; van der Poel, S.; Hoekman, L.; Celie, P.; Joosten, R. P.; Faessler, R.; Perrakis, A.; Sonnenberg, A.

10.1101/2024.03.15.585234 — cell biology — Posted on 2024-03-17

2383 Physiologic media renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

Bussi, C.; Lai, R.; Athanasiadi, N.; Gutierrez, M. G.

10.1101/2024.03.15.585248 — cell biology — Posted on 2024-03-17

2384 Revealing Gene Expression Heterogeneity in a Clonal Population of Tetrahymena thermophila through Single-Cell RNA Sequencing

Kojima, H.; Kashiwagi, A.; Ikegami, T.

10.1101/2023.08.06.551249 — microbiology — Posted on 2024-03-17

2385 Redox-dependent synaptic clustering of gephyrin

Gehling, M.-T.; Liebsch, F.; Jacobs, L.; Riemer, J.; Schwarz, G.

10.1101/2024.03.15.585209 — neuroscience — Posted on 2024-03-17

2386 Cycle-frequency content EEG analysis improves the assessment of respiratory-related cortical activity

Navarro-Sune, X.; Raux, M.; Hudson, A. L.; Similowski, T.; Chavez, M.

10.1101/2024.03.15.585182 — neuroscience — Posted on 2024-03-17

2387 Human cortical neurons rapidly generated by direct ES cell programming integrate into stroke-injured rat cortex

Martinez-Curiel, R.; Hajy, M.; Tsupykov, O.; Jansson, L.; Avaliani, N.; Coll-San Martin, B.; Monni, E.; Skibo, G.; Lindvall, O.; Palma Tortosa, S.; Kokaia, Z.

10.1101/2024.03.15.585240 — neuroscience — Posted on 2024-03-17

2388 Rat primary cortical cell tri-culture to study effects of amyloid-beta on microglia function

Kim, H.; Le, B.; Goshi, N.; Zhu, K.; Grodzki, A. C.; Lein, P. J.; Zhao, M.; Seker, E.

10.1101/2024.03.15.584736 — neuroscience — Posted on 2024-03-17

2389 Low-grade systemic inflammation stimulates microglial turnover and accelerates the onset of Alzheimer's-like pathology

Guerrer-Carrasco, M.; Targett, I.; Olmos-Alonso, A.; Vargas-Caballero, M.; Gomez-Nicola, D.

10.1101/2024.03.15.585224 — neuroscience — Posted on 2024-03-17

2390 Curating models from BioModels: Developing a workflow for creating OMEX files

Xu, J.; Smith, L.

10.1101/2024.03.15.585236 — systems biology — Posted on 2024-03-17

2391 Dynamics of endogenous and water cortisol release in Asian Seabass Lates calcarifer after acute stress in a farm scale recirculating aquaculture system

Tan, M. R.; Aung, K. M. M.; Salleh, N. A. b. M.; Tan, J. Y. A.; Chua, K. X.; Doblado, G. J.; Chua, K. L.; Tham, V.; Lin, J. J.; Chaganty, V.; Yusoff, D. M.; Vij, S.; Su, X.; Sutarlie, L.; Wee, C. L.

10.1101/2023.09.20.558587 — physiology — Posted on 2024-03-17

2392 Prediction of Ca2+ binding site in proteins with a fast and accurate method based on statistical mechanics and analysis of crystal structures

Basit, A.; Choudhury, D.; Bandyopadhyay, P.

10.1101/2024.03.03.583063 — biophysics — Posted on 2024-03-17

2393 Dependence of Nucleosome Mechanical Stability on DNA Mismatches

Ngo, T. T. M.; Liu, B.; Wang, F.; Basu, A.; Wu, C.; Ha, T.

10.1101/2022.11.21.517409 — biophysics — Posted on 2024-03-17

2394 Scvi-hub: an actionable repository for model-driven single cell analysis

Ergen, C.; Pour Amiri, V. V.; Kim, M.; Streets, A.; Gayoso, A.; Yosef, N.

10.1101/2024.03.01.582887 — bioinformatics — Posted on 2024-03-17

2395 Loss of the Na+/K+ cation pump CATP-1 suppresses nekl-associated molting defects

Fay, D. S.; Binti, S.; Edeen, P. T.

10.1101/2024.03.15.585189 — genetics — Posted on 2024-03-17

2396 Dorsomedial Striatal Glutamatergic Transmission Inhibits Binge Drinking in Selectively Bred Crossed High Alcohol Preferring Mice

Boehm, S. L.; Bauer, M.; McVey, M. M.; Zhang, Y.

10.1101/2024.03.15.585024 — neuroscience — Posted on 2024-03-17

2397 Orthogonal IMiD-Degron Pairs Induce Selective Protein Degradation in Cells

Brennan, P. J.; Saunders, R. E.; Spanou, M.; Serafini, M.; Sun, L.; Heger, G. P.; Konopacka, A.; Beveridge, R. D.; Gordon, L.; Bunally, S. B.; Saudemont, A.; Benowitz, A. B.; Martinez-Fleites, C.; Queisser, M. A.; An, H.; Deane, C. M.; Hann, M. M.; Brayshaw, L. L.; Conway, S. J.

10.1101/2024.03.15.585309 — biochemistry — Posted on 2024-03-16

2398 A feedback-driven IoT microfluidic, electrophysiology, and imaging platform for brain organoid studies

10.1101/2024.03.15.585237 — neuroscience — Posted on 2024-03-17

2399 Cell-type specialization of layer 5 excitatory neurons in tactile behavior

King, S. G.; Maire, P.; Mergenthal, A.; Walker, S.; Hires, S. A.

10.1101/2024.03.15.585205 — neuroscience — Posted on 2024-03-17

2400 Neuronal activity promotes axonal node-like clustering prior to myelination and remyelination in the central nervous system.

Ronzano, R.; Perrot, C.; Mazuir, E.; Thetiot, M.; Aigrot, M.-S.; Stheneur, P.; Lejeune, F.-X.; Stankoff, B.; Lubetzki, C.; Sol-Foulon, N.; Desmazieres, A.

10.1101/2024.03.16.585168 — neuroscience — Posted on 2024-03-17

2401 Benchmarking reveals superiority of deep learning variant callers on bacterial nanopore sequence data

Hall, M. B.; Wick, R. R.; Judd, L. M.; Nguyen, A. N. T.; Steinig, E. J.; Xie, O.; Davies, M. R.; Seemann, T.; Stinear, T. P.; Coin, L. J. M.

10.1101/2024.03.15.585313 — bioinformatics — Posted on 2024-03-16

2402 Mechanistic principles of hydrogen evolution in the membrane-bound hydrogenase

Sirohiwal, A.; Gamiz-Hernandez, A. P.; Kaila, V. R. I.

10.1101/2024.03.16.585322 — biochemistry — Posted on 2024-03-16

2403 Structural basis for allosteric regulation of human phosphofructokinase-1

Lynch, E. M.; Hansen, H.; Salay, L. E.; Cooper, M.; Timr, S.; Kollman, J. M.; Webb, B. A.

10.1101/2024.03.15.585110 — biochemistry — Posted on 2024-03-16

2404 Protein disulfide isomerase disassembles stress granules and blocks cytoplasmic aggregation of TDP-43 in ALS

Liu, J.-Q.; Liu, H.; Li, Y.; Liu, X.; Wang, L.-Q.; Wang, K.; Yang, Z.; Fu, Q.; Xu, X.; Chen, J.; Zhang, Y.; Zhou, J.; Le, W.; Cui, M.; Liang, Y.

10.1101/2024.03.16.585334 — biochemistry — Posted on 2024-03-16

2405 A transcription factor (TF) inference method that broadly measures TF activity and identifies mechanistically distinct TF networks

Jones, T.; Sigauke, R. F.; Sanford, L.; Taatjes, D. J.; Allen, M. A.; Dowell, R. D.

10.1101/2024.03.15.585303 — genomics — Posted on 2024-03-16

2406 Ca2+-independent ZmCPK2 is inhibited by Ca2+-dependent ZmCPK17 during drought response in maize

Hu, X.; Cheng, J.; Lu, M.; Zhu, Y.; Fang, T.; Li, Z.; Wang, X.; Wang, Y.; Guo, Y.; Yang, S.; Gong, Z.

10.1101/2024.03.15.585280 — molecular biology — Posted on 2024-03-16

2407 Single-animal, single-tube RNA extraction for quantitative analysis of transcripts in the tardigrade Hypsibius exemplaris

Kirk, M. J.; Xu, C.; Rothman, J. H.

10.1101/2024.03.15.585302 — molecular biology — Posted on 2024-03-16

2408 Alternative silencing states of Transposable Elements in Arabidopsis

Hure, V.; Piron-Prunier, F.; Yehouessi, T.; Vitte, C.; Kornienko, A. E.; Adam, G.; Nordborg, M.; Deleris, A.

10.1101/2024.03.16.585326 — molecular biology — Posted on 2024-03-16

2409 GNN codon adjacency regulates protein translation

Sun, J.; Hwang, P.; Sakkas, E. D.; Zhou, Y.; Perez, L.; Dave, I.; Kwon, J. B.; McMahon, A. E.; Wichman, M.; Raval, M.; Scopino, K.; Krizanc, D.; Thayer, K. M.; Weir, M. P.

10.1101/2024.03.16.583757 — molecular biology — Posted on 2024-03-16

2410 End resection and telomere healing of DNA double-strand breaks during nematode programmed DNA elimination

Estrem, B.; Davis, R. E.; Wang, J.

10.1101/2024.03.15.585292 — molecular biology — Posted on 2024-03-16

2411 Wildlife as a sentinel for pathogen introduction in non-endemic areas: Is Leishmania tropica circulating in wildlife in Spain?

Azami-Conesa, I.; Matas Mendez, P.; Perez-Moreno, P.; Carrion, J.; Alunda, J. M.; Mateo Barrientos, M.; Gomez_Munoz, M. T.

10.1101/2024.03.16.585353 — microbiology — Posted on 2024-03-16

2412 Rapid evolution of Klebsiella pneumoniae biofilms in vitro delineates adaptive changes selected during infection

Zaborskyte, G.; Coelho, P.; Wrande, M.; Sandegren, L.

10.1101/2024.03.16.585345 — microbiology — Posted on 2024-03-16

2413 Bottlenecks in the Implementation of Genome Scale Metabolic Model Based Designs for Bioproduction from Aromatic Carbon Sources

Banerjee, D.; Menasalvas, J.; Chen, Y.; Gin, J. W.; Baidoo, E. E.; Petzold, C. J.; Eng, T.; Mukhopadhyay, A.

10.1101/2024.03.15.585139 — microbiology — Posted on 2024-03-16

2414 Multiplexed screen identifies a Pseudomonas aeruginosa-specific small molecule targeting the outer membrane protein OprH and its interaction with LPS

Warrier, T.; Poulsen, B. E.; Barkho, S.; Bagnall, J.; Romano, K. P.; White, T.; Yu, X.; Kawate, T.; Nguyen, P. H.; Raines, K.; Ferrara, K.; Golas, A.; Fitzgerald, M.; Boeszoermenyi, A.; Kaushik, V.; Serrano-Wu, M.; Shoresh, N.; Hung, D. T.

10.1101/2024.03.16.585348 — microbiology — Posted on 2024-03-16

2415 Impact of Chemical Dynamics of Commercial PURE Systems on Malachite Green Aptamer Fluorescence

Jurado, Z.; Murray, R. M.

10.1101/2024.03.15.585317 — synthetic biology — Posted on 2024-03-16

2416 AutoPeptideML: A study on how to build more trustworthy peptide bioactivity predictors

Fernandez-Diaz, R.; Cossio-Perez, R.; Agoni, C.; Hoang, L. T.; Lopez, V.; Shields, D. C.

10.1101/2023.11.13.566825 — bioinformatics — Posted on 2024-03-16

2417 Neurexins control the strength and precise timing of glycinergic inhibition in the auditory brainstem

Jiang, H.-H.; Xu, R.; Nie, X.; Su, Z.; Xu, X.; Pang, R.; Zhou, Y.; Luo, F.

10.1101/2023.12.14.571678 — neuroscience — Posted on 2024-03-16

2418 Detection of spatial chromatin accessibility patterns with inter-cellular correlations

Chen, X.; Li, K.; Wu, X.; Li, Z.; Jiang, Q.; Wu, Y.; Jiang, R.

10.1101/2024.03.09.584249 — bioinformatics — Posted on 2024-03-16

2419 The power and limits of predicting exon-exon interactions using protein 3D structures

Liebold, J.; Del Moral-Morales, A.; Manalastas-Cantos, K.; Tsoy, O.; Kurtz, S.; Baumbach, J.; Newaz, K.

10.1101/2024.03.01.582917 — bioinformatics — Posted on 2024-03-16

2420 Loss of Lamin A leads to the nuclear translocation of AGO2 and compromised RNA interference

Lobo, V.; Nowak, I.; Fernandez, C.; Correa Muler, A. I.; Westholm, J. O.; Huang, H.-C.; Fabrik, I.; Huynh, H. T.; Shcherbinina, E.; Poyraz, M.; Hartlova, A.; Benhalevy, D.; Angeletti, D.; Sarshad, A. A.

10.1101/2023.06.05.543674 — biochemistry — Posted on 2024-03-16

2421 Evolution of ion channels in cetaceans a natural experiment in the tree of life

Uribe, C.; Nery, M.; Zavala, K.; Mardones, G.; Riadi, G.; Opazo, J.

10.1101/2023.06.15.545160 — evolutionary biology — Posted on 2024-03-16

2422 Y-chromosomal microsatellites and expansion from Africa

Cenac, Z.

10.1101/2023.04.29.538812 — evolutionary biology — Posted on 2024-03-16

2423 Microbial utilisation of maize rhizodeposits applied to an agricultural soil at a range of concentrations

Niedeggen, D.; Rueger, L.; Oburger, E.; Santangeli, M.; Ahmed, M.; Vetterlein, D.; Blagodatsky, S.; Bonkowski, M.

10.1101/2024.03.15.585161 — ecology — Posted on 2024-03-16

2424 Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging

Bandyopadhyay, S.; Duffy, M.; Ahn, K. J.; Pang, M.; Smith, D.; Duncan, G.; Sussman, J.; Zhang, J.; Huang, J.; Lin, Y. L.; Xiong, B.; Imtiaz, T.; Chen, C.-h.; Thadi, A.; Chen, C.; Xu, J.; Reichart, M.; Pillai, V.; Snaith, O.; Oldridge, D.; Bhattacharyya, S.; Maillard, I. H.; Carroll, M.; Nelson, C.; Qin, L.; Tan, K.

10.1101/2024.03.14.585083 — cell biology — Posted on 2024-03-16

2425 Cohesin regulates promoter-proximal pausing of RNA Polymerase II by limiting recruitment of super elongation complex

Tei, S.; Sakata, T.; Yoshimura, A.; Natsume, T.; Kanemaki, M. T.; Bando, M.; Shirahige, K.

10.1101/2024.03.15.584908 — molecular biology — Posted on 2024-03-16

2426 Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy

Zborowsky, S.; Seurat, J.; Balacheff, Q.; Minh, C. N. N.; Titecat, M.; Evrard, E.; Rodriguez-Gonzalez, R. A.; Marchi, J.; Weitz, J. S.; Debarbieux, L.

10.1101/2024.01.16.575879 — microbiology — Posted on 2024-03-16

2427 C1q/MASP complexes - hybrid complexes of classical and lectin pathway proteins are found in the circulation

Rosbjerg, A.; Plchov, T. A.; Bayarri-Olmos, R.; Holm, B. E.; Pedersen, I. S.; Skjoedt, M.-O.; Garred, P.

10.1101/2024.03.15.584944 — immunology — Posted on 2024-03-16

2428 The resolution of face perception varies systematically across the visual field

Morsi, A.; Goffaux, V.; Greenwood, J. A.

10.1101/2023.08.10.552592 — neuroscience — Posted on 2024-03-16

2429 M2M-InvNet: Human Motor Cortex Mapping from Multi-Muscle Response Using TMS and Generative 3D Convolutional Network

Akbar, M. N.; Yarossi, M.; Rampersad, S.; Lockwood, K.; Masoomi, A.; Tunik, E.; Brooks, D.; Erdogmus, D.

10.1101/2022.07.22.501062 — neuroscience — Posted on 2024-03-16

2430 Contradictory behavioral effects of neuronal perturbations on behavioral responses to linearly polarized light in freely walking Drosophila

Titova, A. V.; Straw, A. D.

10.1101/2024.03.15.584848 — neuroscience — Posted on 2024-03-16

2431 Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduria

Denley, M. C. S.; Straub, M. S.; Marcionelli, G.; Güra, M. A.; Penton Ribas, D.; Delvendahl, I.; Poms, M.; Vekeriotaite, B.; Conte, F.; von Meyenn, F.; Froese, D. S.; Baumgartner, M. R.

10.1101/2024.03.15.585183 — neuroscience — Posted on 2024-03-16

2432 Corticostriatal responses to social reward are linked to trait reward sensitivity and subclinical substance use in young adults

Wyngaarden, J. B.; Johnston, C. R.; Sazhin, D.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M.; Alloy, L. B.; Smith, D. V.; Jarcho, J. M.

10.1101/2023.01.17.524305 — neuroscience — Posted on 2024-03-16

2433 Nuclear translocation of LINE-1 ORF1p alters nuclear envelope integrity and disrupts nucleocytoplasmic transport in human neurons

Znaidi, R.; Massiani-Beaudoin, O.; Mailly, P.; Monnet, H.; The Brainbank Neuro- CEB Neuropathology Network, ; Joshi, R. L.; Fuchs, J.

10.1101/2023.08.10.552479 — neuroscience — Posted on 2024-03-16

2434 Revealing intact neuronal circuitry in centimeter-sized formalin-fixed paraffin-embedded brain

Lin, Y.-H.; Wang, L.-W.; Chen, Y.-H.; Chan, Y.-C.; Hu, S.-H.; Wu, S.-Y.; Chiang, C.-S.; Huang, G.-J.; Yang, S.-D.; Chu, S.-W.; Wang, K.-C.; Lin, C.-H.; Huang, P.-H.; Cheng, H.-J.; Chen, B.-C.; Chu, L.-A.

10.1101/2022.11.28.518189 — neuroscience — Posted on 2024-03-16

2435 An optimized somatic embryo transformation system assisted homozygous edited rubber tree generation method mediated by CRISPR/Cas9

Yang, X.; Lin, Q.; Udayabhanu, J.; Hua, Y.; Dai, X.; Xin, S.; Huang, H.; Huang, T.

10.1101/2024.03.14.585007 — plant biology — Posted on 2024-03-16

2436 Thoracic epidural blockade after myocardial infarction benefits from anti-arrhythmic pathways mediated in part by parasympathetic modulation

Hoang, J. D.; Van Weperen, V. Y.; Kang, K.-W.; Jani, N.; Swid, M. A.; Chan, C. A.; Lokhandwala, Z. A.; Lux, R. L.; Vaseghi, M.

10.1101/2024.03.14.585127 — physiology — Posted on 2024-03-16

2437 Direct measurement of RNA Polymerase II hypertranscription in cancer FFPE samples

Henikoff, S.; Henikoff, J. G.; Paranal, R. M.; Greene, J. E.; Zheng, Y.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.; Ahmad, K.

10.1101/2024.02.28.582647 — cancer biology — Posted on 2024-03-16

2438 Assessing the hydromechanical control of plant growth

Laplaud, V.; Muller, E.; Demidova, N.; Drevensek, S.; Boudaoud, A.

10.1101/2023.09.21.558781 — biophysics — Posted on 2024-03-16

2439 DNA barcoding and species delimitation based on four Chloroplast loci to identify species within the Elaeocarpaceae family

Khushwaha, J.; Joshi, A.; Das, S. K.

10.1101/2024.03.14.585135 — bioinformatics — Posted on 2024-03-16

2440 BMP2 binds non-specifically to PEG-passivated biomaterials and induces substantial signaling

Le Pennec, J.; Guibert, A.; Vives, R. R.; Migliorini, E.

10.1101/2024.03.14.585026 — bioengineering — Posted on 2024-03-16

2441 Elongation capacity of polyunsaturated fatty acids in the annelid Platynereis dumerilii

Ramos-Llorens, M.; Bainour, K.; Adelmann, L.; Hontoria, F.; Navarro, J. C.; Raible, F.; Monroig, O.

10.1101/2024.03.15.584978 — biochemistry — Posted on 2024-03-16

2442 Aedes albopictus colonies from different geographic origins differ in their sleep and activity levels but not in the time of peak activity

Wynne, N. E.; Applebach, E.; Chandrasegaran, K.; Ajayi, O. M.; Chakraborty, S.; Bonizzoni, M.; Lahondere, C.; Benoit, J. B.; Vinauger, C.

10.1101/2024.03.15.585187 — animal behavior and cognition — Posted on 2024-03-16

2443 Loss of the Na+/K+ cation pump CATP-1 suppresses nekl-associated molting defects

Fay, D. S.; Binti, S.; Edeen, P. T.

10.1101/2024.03.15.585189 — genetics — Posted on 2024-03-16

2444 Robust and Accurate Bayesian Inference of Genome-Wide Genealogies for Large Samples

Deng, Y.; Nielsen, R.; Song, Y. S.

10.1101/2024.03.16.585351 — genetics — Posted on 2024-03-16

2445 Analyzing bivariate cross-trait genetic architecture in GWAS summary statistics with the BIGA cloud computing platform

Li, Y.; Xue, F.; Li, B.; Yang, Y.; Fan, Z.; Shu, J.; Yang, X.; Wang, X.; Lin, J.; Copana, C.; Zhao, B.

10.1101/2023.04.28.538585 — genetics — Posted on 2024-03-16

2446 First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: Dispelling previous anecdotes

Lardeux, F.; Bousses, P.; Tejerina, R.; Berger, A.; Barnabe, C.; Garcia, L.

10.1101/2024.03.14.585027 — ecology — Posted on 2024-03-16

2447 Thermal environment and ecological interactions modulate the importance of evolution in response to warming

Faillace, C. A.; Alvarez-Codesal, S.; Garreau, A.; Bestion, E.; Montoya, J. M.

10.1101/2023.09.28.559813 — ecology — Posted on 2024-03-16

2448 Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution

Feulner, L.; Wuennemann, F.; Liang, J.; Hofmann, P.; Hitz, M.-P.; Schapiro, D.; Leclerc, S.; van Vliet, P. P.; Andelfinger, G.

10.1101/2024.03.05.583423 — developmental biology — Posted on 2024-03-16

2449 Redefining the role of Hypoxia-inducible factors (HIFs) in oxygen homeostasis

Fernandez Arias, C.; Acosta, F. J.; Bertocchini, F.; Fernandez-Arias, C.

10.1101/2024.03.15.585157 — cell biology — Posted on 2024-03-16

2450 Inhibition of Proteasome Activity Facilitates Definitive Endodermal Specification of pluripotent Stem Cells by influencing YAP signaling

Ashok, A.; Ashwatnarayan, A.; Bhaskar, S.; Shekar, S.; Prasanna, J.; KUMAR, A.

10.1101/2024.03.15.585134 — cell biology — Posted on 2024-03-16

2451 cGAS-STING is responsible for aging of telomerase deficient zebrafish

Serifoglu, N.; Allavena, G.; Bastos-Lopes, B.; Marzullo, M.; Bousounis, P.; Trompouki, E.; Ferreira, M. G.

10.1101/2024.03.11.584360 — cell biology — Posted on 2024-03-16

2452 RNA 3' end tailing safeguards cells against products of pervasive transcription termination

Wu, G.; Rouviere, J. O.; Schmid, M.; Jensen, T. H.

10.1101/2024.03.15.584960 — molecular biology — Posted on 2024-03-16

2453 A Mycobacterium tuberculosis secreted virulence factor disrupts host snRNP biogenesis

Chauhan, K.; Passricha, N.; Kapoor, Y.; Datta, D.; Arora, N.; Das, M.; Rao, K.; Singh, L.; Dutt, R.; Sharma, R.; Sarkar, B.; Malakkar, B.; Saini, P.; Mehra, L.; Das, P.; Ahuja, V.; Singhal, A.; Nandicoori, V.; Kumar, D.

10.1101/2024.02.06.579120 — molecular biology — Posted on 2024-03-16

2454 CD40 is an immune checkpoint regulator that potentiates myocardial inflammation through activation and expansion of CCR2+ macrophages and CD8 T-cells

Jimenez, J.; Amrute, J.; Ma, P.; Wang, X.; Dai, R.; Lavine, K.

10.1101/2024.03.14.584418 — immunology — Posted on 2024-03-16

2455 The role of desmoplakin for neuronal function in the dentate gyrus and anxiety-related behavior

Otsubo, K.; Sakashita, N.; Nishimoto, Y.; Sato, Y.; Kobayashi, K.; Suzuki, K.; Segi-Nishida, E.

10.1101/2023.11.17.567646 — neuroscience — Posted on 2024-03-16

2456 Even Small Visual Latencies Can Profoundly Impair Implicit Sensorimotor Learning

Hadjiosif, A. M.; Abraham, G.; Ranjan, T.; Smith, M. A.

10.1101/2024.03.14.585093 — neuroscience — Posted on 2024-03-16

2457 Dynamin-2 Mutations Linked to Neonatal-onset Centronuclear Myopathy impair exocytosis and endocytosis in adrenal chromaffin cells.

Bayones, L.; Guerra-Fernandez, M. J.; Figuroa-Cares, C.; Gallo, L. I.; Alfonso-Bueno, S.; Baez-Matus, X.; Gonzalez-Jamett, A.; Cardenas, A. M.; Marengo, F. D.

10.1101/2024.03.07.583689 — neuroscience — Posted on 2024-03-16

2458 Correspondence of fentanyl brain pharmacokinetics and behavior measured via engineering opioids biosensors and computational ethology

Muthusamy, A. K.; Rosenberg, M.; Kim, C. H.; Wang, A. Z.; Ebisu, H.; Chin, T. M.; Koranne, A.; Marvin, J. S.; Cohen, B. N.; Looger, L. L.; Oka, Y.; Meister, M.; Lester, H. A.

10.1101/2024.03.15.584894 — neuroscience — Posted on 2024-03-16

2459 Molecular dissection of HERV-W dependent microglial- and astroglial cell polarization

Gruchot, J.; Reiche, L.; Werner, L.; Herrero, F.; Schira-Heinen, J.; Meyer, U.; Kuery, P.

10.1101/2024.03.15.584408 — neuroscience — Posted on 2024-03-16

2460 Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms

Lambourne, L.; Mattioli, K.; Santoso, C.; Sheynkman, G.; Inukai, S.; Kaundal, B.; Berenson, A.; Spirohn-Fitzgerald, K.; Bhattacharjee, A.; Rothman, E.; Shrestha, S.; Laval, F.; Yang, Z.; Bisht, D.; Sewell, J. A.; Li, G.; Prasad, A.; Phanor, S.; Lane, R.; Campbell, D. M.; Hunt, T.; Balcha, D.; Gebbia, M.; Twizere, J.-C.; Hao, T.; Frankish, A.; Riback, J.; Salomonis, N.; Calderwood, M. A.; Hill, D. E.; Sahni, N.; Vidal, M.; Bulyk, M. L.; Fuxman Bass, J. I.

10.1101/2024.03.12.584681 — systems biology — Posted on 2024-03-16

2461 Quantitative effects of co-culture on T cell motility and cancer-T cell interactions

Li, X.; Jin, T.; Wang, L.; Li, M.; Han, W.; Li, X.

10.1101/2024.03.15.585166 — systems biology — Posted on 2024-03-16

2462 Understanding the effects of oxytocin receptor variants on OXT-OXT receptor binding: A mathematical model

Dubey, P.; Fang, Y.; Tukei, K. L.; Kuila, S.; Liu, X.; Sahota, A.; Frolova, A. I.; Reinl, E. L.; Malik, M.; England, S. K.; Imoukhuede, P. I.

10.1101/2024.02.28.582600 — systems biology — Posted on 2024-03-16

2463 Decoding strawberry volatile cultivar diversity through comparative transcriptome analysis

Passa, K.; Tsormpatsidis, E.; Ganopoulos, I.; Bazakos, C.; Papasotiropoulos, V.

10.1101/2024.03.14.584999 — plant biology — Posted on 2024-03-16

2464 Postembryonic developmental roles of the Arabidopsis KEULE gene

Ruiz-Bayon, A.; Cara-Rodriguez, C.; Sarmiento-Manus, R.; Munoz-Viana, R.; Lozano, F. M.; Ponce, M. R.; Micol, J. L.

10.1101/2024.03.14.585090 — plant biology — Posted on 2024-03-16

2465 A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation

Yu, W.; Li, M.; Wang, W.; Zhuang, H.; Luo, J.; Sang, Y.; Segonzac, C.; Macho, A. P.

10.1101/2024.03.15.585124 — plant biology — Posted on 2024-03-16

2466 EHMT2 Inactivation in Pancreatic Epithelial Cells Shapes the Transcriptional Landscape and Inflammation Response of the Whole Pancreas

Pollin, G.; Mathison, A.; Milech de Assuncao, T.; Thomas, A.; Zeighami, L.; Salmonson, A.; Liu, H.; Urrutia, G.; Vankayala, P.; Pandol, S. J.; Zimmermann, M. T.; Iovanna, J. L.; Jin, V. X.; Urrutia, R. A.; Lomberk, G. A.

10.1101/2024.03.14.584700 — cancer biology — Posted on 2024-03-16

2467 Impact of genomic background and developmental state on signaling pathways and response to therapy in Glioblastoma patient-derived cells

10.1101/2024.03.14.585115 — cancer biology — Posted on 2024-03-16

2468 Targeting Leishmania infantum Mannosyl-oligosaccharide glucosidase with natural products: pH-dependent inhibition explored through computer-aided drug design.

Goyzueta Mamani, L. D.; Barazorda Ccahuana, H. L.; Candia Puma, M. A.; Sobreira Galdino, A.; Machado de Avila, R. A.; Cordeiro Giunchetti, R.; Medina Franco, J. L.; Florin Christensen, M.; Chavez Fumagalli, M. A.

10.1101/2024.03.14.585122 — bioinformatics — Posted on 2024-03-16

2469 Effect of dataset partitioning strategies for evaluating out-of-distribution generalisation for predictive models in biochemistry

Fernandez-Diaz, R.; Hoang, T. L.; Lopez, V.; Shields, D. C.

10.1101/2024.03.14.584508 — bioinformatics — Posted on 2024-03-16

2470 The Hitchhiker's Guide to Sequencing Data Types and Volumes for Population-Scale Pangenome Construction

Sarashetti, P.; Lipovac, J.; Tomas, F.; Sikic, M.; Liu, J.

10.1101/2024.03.14.585029 — bioinformatics — Posted on 2024-03-16

2471 Modeling interpretable correspondence between cell state and perturbation response with CellCap

Xu, Y.; Fleming, S.; Tegtmeyer, M.; McCarroll, S. A.; Babadi, M.

10.1101/2024.03.14.585078 — bioinformatics — Posted on 2024-03-16

2472 Photoactivatable Blue Fluorescent Protein

Gaytan, P.; Roldan-Salgado, A.

10.1101/2023.12.12.571285 — biochemistry — Posted on 2024-03-16

2473 Sparse Testing Designs for Optimizing Predictive Ability in Sugarcane Populations

Garcia-Abadillo, J.; Adunola, P.; Aguilar, F. S.; Trujillo-Montenegro, J. H.; Riascos, J. J.; Persa, R.; Isidro Y Sanchez, J.; Jarquin, D.

10.1101/2024.03.14.584687 — genomics — Posted on 2024-03-16

2474 Exploring the probiotic potential, antioxidant capacity, and healthy aging based on whole genome analysis of Lactiplantibacillus plantarum LPJBC5 isolated from fermented milk product

Bhattacharya, A.; Joishy, T. K.; Khan, M. R.

10.1101/2024.03.14.584937 — genomics — Posted on 2024-03-16

2475 Transposable element methylation state predicts age and disease

Morandini, F.; Lu, J. Y.; Rechsteiner, C.; Shadyab, A. H.; Casanova, R.; Snively, B.; Seluanov, A.; Gorbunova, V.

10.1101/2024.03.15.585206 — genomics — Posted on 2024-03-16

2476 A first look at the genome structure of hexaploid 'Black Mitcham' peppermint (Mentha piperita L.)

Talbot, S. C.; Vining, K. J.; Lange, B. M.; Pandelova, I.

10.1101/2024.03.15.585188 — genomics — Posted on 2024-03-16

2477 Advancing marker-gene-based methods for prokaryote-mediated multifunctional redundancy: exploring random and nonrandom extinctions in a watershed

Cheng, W.-H.; Miki, T.; Ido, M.; Yoneya, K.; Matsui, K.; Yokokawa, T.; Yamanaka, H.; Nakano, S.-i.

10.1101/2024.03.14.584931 — ecology — Posted on 2024-03-16

2478 Extreme temperatures impede the release success of captive-bred avian scavengers

Anglister, N.; Acacio, M.; Vaadia, G.; Arnon, E. A.; Bruer, M. B.; Hatzofe, O.; Miller, Y.; King, R.; Pinter-Wollman, N.; Spiegel, O.

10.1101/2024.03.14.585025 — ecology — Posted on 2024-03-16

2479 Hox-A2 protein expression in avian jaws cartilages and muscle primordia development

Louryan, S. M.; Duterre, M.; Vanmuylder, N.

10.1101/2024.03.14.584976 — developmental biology — Posted on 2024-03-16

2480 Abnormal global longitudinal strain and reduced serum inflammatory markers in cardiac AL amyloidosis patients without significant amyloid fibril deposition

Edwards, C. V.; Ferri, G. M.; Villegas-Galaviz, J.; Ghosh, S.; Singh Bawa, P.; Wang, F.; Klimtchuk, E.; Ajayi, T. B.; Morgan, G. J.; Prokaeva, T.; Staron, A.; Ruberg, F. L.; Sanchorawala, V.; Giadone, R. M.; Murphy, G. J.

10.1101/2024.03.14.584987 — cell biology — Posted on 2024-03-16

2481 Development of the 12-base short dimeric myogenetic oligodeoxynucleotide that induces myogenic differentiation

Umezawa, K.; Ikeda, R.; Sakamoto, T.; Enomoto, Y.; Nihashi, Y.; Shinji, S.; Shimosato, T.; Kagami, H.; Takaya, T.

10.1101/2024.03.14.584904 — cell biology — Posted on 2024-03-16

2482 Global Release of Translational Repression Across Plasmodiums Host-to-Vector Transmission Event

Rios, K. T.; McGee, J. P.; Sebastian, A.; Moritz, R. L.; Feric, M.; Absalon, S.; Swearingen, K. E.; Lindner, S. E.

10.1101/2024.02.01.577866 — microbiology — Posted on 2024-03-16

2483 Parvalbumin interneuron mGlu5 receptors govern sex differences in prefrontal cortex physiology and binge drinking

Fabian, C. B.; Jordan, N. D.; Cole, R. H.; Carley, L. G.; Thompson, S. M.; Seney, M. L.; Joffe, M. E.

10.1101/2023.11.20.567903 — neuroscience — Posted on 2024-03-16

2484 Enhanced efficiency in the bilingual brain through the inter-hemispheric cortico-cerebellar pathway in early second language acquisition

Gracia-Tabuenca, Z.; Barbeau, E. B.; Kousaie, S.; Chen, J.-K.; Chai, X. J.; Klein, D.

10.1101/2023.11.16.567455 — neuroscience — Posted on 2024-03-16

2485 Microglia contact cerebral vasculature through gaps between astrocyte endfeet

Morris, G. P.; Foster, C. G.; Sutherland, B. A.; Grubb, S.

10.1101/2024.03.14.585114 — neuroscience — Posted on 2024-03-16

2486 Laying the Foundation: Modern Transformers for Gold-Standard Sleep Analysis

Coon, W. G.; Ogg, M.

10.1101/2024.01.18.576246 — neuroscience — Posted on 2024-03-16

2487 Non-Negative Matrix Factorization for Analyzing State Dependent Neuronal Network Dynamics in Calcium Recordings

Carbonero, D.; Noueihed, J.; Kramer, M. A.; White, J. A.

10.1101/2023.10.11.561797 — neuroscience — Posted on 2024-03-16

2488 High-throughput analysis of dendritic and axonal arbors reveals transcriptomic correlates of neuroanatomy

Gliko, O.; Mallory, M.; Dalley, R.; Gala, R.; Gornet, J.; Zeng, H.; Sorensen, S.; Sumbul, U.

10.1101/2022.03.07.482900 — neuroscience — Posted on 2024-03-16

2489 Task-related modulation of event-related potentials does not reflect changes to sensory representations

Rideaux, R.

10.1101/2024.01.20.576485 — neuroscience — Posted on 2024-03-16

2490 Septo-hypothalamic regulation of binge-like alcohol consumption by the nociceptin system.

Haun, H.; Hernandez, R.; Yan, L.; Flanigan, M.; Hon, O.; Lee, S.; Mendez, H.; Roland, A.; Taxier, L.; kash, T. L.

10.1101/2024.03.14.585116 — neuroscience — Posted on 2024-03-16

2491 Neural correlates in the time course of inferences: costs and benefits for less-skilled readers at university level.

Urrutia, M.; Pino, E.; Troncoso-Seguel, M.; Bustos, C.; Guevara, P.; Torres-Ocampo, K.; Mariangel, S.; Fu, Y.; Marrero, H.

10.1101/2024.03.14.585085 — neuroscience — Posted on 2024-03-16

2492 AGE READINGS AND ASSESSMENT IN COASTAL BATOID ELASMOBRANCHS FROM SMALL-SCALE SIZE-SELECTIVE FISHERY: THE IMPORTANCE OF DATA COMPARABILITY IN MULTISPECIFIC ASSEMBLAGES.

Scacco, U.; Zanardi, F.; Kroha, S.; Mancini, E.; Tiralongo, F.; Nascetti, G.

10.1101/2024.03.15.585164 — zoology — Posted on 2024-03-16

2493 A distributed integral control mechanism for the regulation of cholesterol concentration in the human retina.

Scheepers, R.; Levi, N. L.; Araujo, R. P.

10.1101/2024.03.14.584346 — systems biology — Posted on 2024-03-16

2494 Graphical pangenomics-enabled characterisation of structural variant impact on gene expression in Brassica napus

Golicz, A. A.; Yildiz, G.; Weber, S.; Kox, T.; Abbadi, A.; Snowdon, R. J.; Zanini, S. F.

10.1101/2024.03.14.585028 — plant biology — Posted on 2024-03-16

2495 The transcription factor ATML1 maintains giant cell identity by inducing synthesis of its own (very) long-chain fatty acid-containing ligands

Vadde, B. V. L.; Russell, N. J.; Bagde, S. R.; Askey, B.; Saint-Antoine, M. M.; Brownfield, B. A.; Mughal, S.; Apprill, L. E.; Khosla, A.; Clark, F. K.; Schwarz, E. M.; Alseekh, S.; Fernie, A. R.; Singh, A.; Schrick, K.; Fromme, J. C.; Skirycz, A.; Formosa-Jordan, P.; Roeder, A. H. K.

10.1101/2024.03.14.584694 — plant biology — Posted on 2024-03-16

2496 Germline cis variant determines epigenetic regulation of the anti-cancer drug metabolism gene dihydropyrimidine dehydrogenase (DPYD)

Zhang, T.; Ambrodji, A.; Huang, H.; Bouchonville, K. J.; Etheridge, A. S.; Schmidt, R. E.; Bembenek, B. M.; Temesgen, Z. B.; Wang, Z.; Innocenti, F.; Stroka, D.; Diasio, R. B.; Largiader, C. R.; Offer, S. M.

10.1101/2023.11.01.565230 — pharmacology and toxicology — Posted on 2024-03-16

2497 Lack of dominant-negative activity for tumor-related ZNRF3 missense mutations at endogenous levels

Smits, R.; Li, S.; Niu, J.; Zhang, R.; Massaar, S.; Merode, J. v.; Schipper, N. d.; Kamp, L. v. d.; Peppelenbosch, M. P.

10.1101/2024.03.14.585013 — cancer biology — Posted on 2024-03-16

2498 A Novel ex-vivo platform for personalized treatment in metastatic ovarian cancer.

Valdivia, A.; Adefulajo, R. A.; Thang, M.; Cuaboy, L. A.; John, C.; Mann, B. E.; Satterlee, A. B.; Bae-Jump, V.; Hingtgen, S. D.

10.1101/2024.03.14.585117 — cancer biology — Posted on 2024-03-16

2499 Understanding the binding mechanisms of Alzheimer risk factor TREM2 in lipid bilayer using multi-scale molecular dynamics simulations

Zhong, Z.; Ulmschneider, M.; Lorenz, C.

10.1101/2024.03.08.584168 — biophysics — Posted on 2024-03-16

2500 Helical Twists and beta-Turns in Structures at Serine-Proline Sequences: Stabilization of cis-Proline and type VI beta-turns via C-H/O interactions

Oven, H. C.; Yap, G. P. A.; Zondlo, N. J.

10.1101/2024.03.14.585129 — biophysics — Posted on 2024-03-16

2501 Cigarette smoking drives accelerated aging across human tissues

Ramirez, J. M.; Ribeiro, R.; Soldatkina, O.; Moraes, A.; Garcia-Perez, R.; Ferreira, P. G.; Mele, M.

10.1101/2024.03.14.585016 — bioinformatics — Posted on 2024-03-16

2502 Machine learning-based prediction of fish acute mortality: Implementation, interpretation, and regulatory relevance

Gasser, L.; Schuer, C.; Perez-Cruz, F.; Schirmer, K.; Baity Jesi, M.

10.1101/2024.03.14.584983 — bioinformatics — Posted on 2024-03-16

2503 Integration of molecular coarse-grained model into geometric representation learning framework for protein-protein complex property prediction

Yue, Y.; Li, S.; Cheng, Y.; Zhu, Z.; Wang, L.; Hou, T.; He, S.

10.1101/2024.03.14.585015 — bioinformatics — Posted on 2024-03-16

2504 ArtiDock: fast and accurate machine learning approach to protein-ligand docking based on multimodal data augmentation

Voitsitskyi, T.; Yesylevskyy, S.; Bdzhola, V.; Stratiichuk, R.; Koleiev, I.; Ostrovsky, Z.; Vozniak, V.; Khropachov, I.; Henitsoi, P.; Popryho, L.; Zhytar, R.; Nafiiev, A.; Starosyla, S.

10.1101/2024.03.14.585019 — bioinformatics — Posted on 2024-03-16

2505 HUHgle: An Interactive Substrate Design Tool for Covalent Protein-ssDNA Labeling Using HUH-tags

Smiley, A. T.; Babilonia-Diaz, N. S.; Hughes, A. J.; Lemmex, A. C.; Anderson, M. J.; Tompkins, K. J.; Gordon, W. R.

10.1101/2024.03.15.585203 — bioinformatics — Posted on 2024-03-16

2506 Cancer Stemness Online: A resource for investigating cancer stemness and associations with immune response

Zhou, W.; Su, M.; Jiang, T.; Xie, Y.; Shi, J.; Ma, Y.; Xu, K.; Xu, G.; Li, Y.; Xu, J.

10.1101/2024.03.14.585118 — bioinformatics — Posted on 2024-03-16

2507 Stereochemically-aware bioactivity descriptors for uncharacterized chemical compounds

Comajuncosa-Creus, A.; Lenes, A.; Sanchez-Palomino, M.; Aloy, P.

10.1101/2024.03.15.584974 — bioinformatics — Posted on 2024-03-16

2508 BayesianSSA: a Bayesian statistical model based on structural sensitivity analysis for predicting responses to enzyme perturbations in metabolic networks

Hosoda, S.; Iwata, H.; Miura, T.; Tanabe, M.; Okada, T.; Mochizuki, A.; Sato, M.

10.1101/2024.03.14.585120 — bioinformatics — Posted on 2024-03-16

2509 MetaDIA: A Novel Database Reduction Strategy for DIA Human Gut Metaproteomics

Duan, H.; Ning, Z.; Sun, Z.; Guo, T.; Sun, Y.; Figeys, D.

10.1101/2024.03.14.585104 — bioinformatics — Posted on 2024-03-16

2510 Comprehensive detection and characterization of human druggable pockets through novel binding site descriptors

Comajuncosa-Creus, A.; Jorba, G.; Barril, X.; Aloy, P.

10.1101/2024.03.14.584971 — bioinformatics — Posted on 2024-03-16

2511 A Hybrid Diffusion Model for Stable, Affinity-Driven, Receptor-Aware Peptide Generation

Ramasubramanian, V. S.; Choudhuri, S.; Ghosh, B.

10.1101/2024.03.14.584934 — bioinformatics — Posted on 2024-03-16

2512 Microbiome single cell atlases generated with a commercial instrument

Li, X.; Xu, L.; Demaree, B.; Noecker, C.; Bisanz, J. E.; Weisgerber, D. W.; Modavi, C.; Turnbaugh, P. J.; Abate, A. R.

10.1101/2023.08.08.551713 — bioengineering — Posted on 2024-03-16

2513 High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics

Tang, K.; Zhou, X.; Fang, S.-Y.; Vandenbulcke, E.; Du, A.; Shen, J.; Cao, H.; Zhou, J.; Chen, K.; Xin, S.; Zhou, L.; Lin, S. H.; Majety, M.; Ling, X.; Lam, S. Z.; Chow, R.; Bai, S.; Nottoli, T.; Booth, C.; Liu, C.; Dong, M. B.; Chen, S.

10.1101/2024.03.14.585126 — bioengineering — Posted on 2024-03-16

2514 In Situ-Crosslinked Zippersomes Enhance Cardiac Repair by Increasing Accumulation and Retention

Jasiewicz, N.; Mei, K.-C.; Oh, H.; Bonacquisti, E.; Chaudhari, A.; Byrum, C.; Jensen, B.; Nguyen, J.

10.1101/2024.03.14.585030 — bioengineering — Posted on 2024-03-16

2515 Pivotal role of biallelic frequency analysis in identifying copy number alterations using genome-wide methods in tumors with a high level of aneuploidy

Rymuza, J.; Woroniecka, R.; Grygalewicz, B.; Bujko, M.

10.1101/2024.03.14.584989 — genomics — Posted on 2024-03-16

2516 Dissection of core promoter syntax through single nucleotide resolution modeling of transcription initiation

He, A. Y.; Danko, C. G.

10.1101/2024.03.13.583868 — genomics — Posted on 2024-03-16

2517 Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis

Sampathkumar, A.; Chen, Z.; Tang, Y.; Fujita, Y.; Ito, M.; Shinohara, A.

10.1101/2023.09.01.555993 — genetics — Posted on 2024-03-16

2518 Post-GWAS functional analyses of CNTNAP5 suggests its role in glaucomatous neurodegeneration

Chakraborty, S.; Sarma, J.; Roy, S. S.; Mitra, S.; Bagchi, S.; Das, S.; Saha, S.; Mahapatra, S.; Bhattacharjee, S.; Maulik, M.; Acharya, M.

10.1101/2024.03.14.583830 — genetics — Posted on 2024-03-16

2519 Convergent origin and accelerated evolution of vesicle-associated RhoGAP proteins in two unrelated parasitoid wasps

Colinet, D.; Cavigliasso, F.; Leobold, M.; Pichon, A.; Urbach, S.; Cazes, D.; Poullet, M.; Belghazi, M.; Volkoff, A.-N.; Drezen, J.-M.; Gatti, J.-L.; Poirie, M.

10.1101/2023.06.05.543686 — evolutionary biology — Posted on 2024-03-16

2520 The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference

Behruznia, M.; Marin, M.; Farhat, M. R.; Thomas, J. C.; Domingo-Sananes, M. R.; Meehan, C. J.

10.1101/2024.03.12.584580 — evolutionary biology — Posted on 2024-03-16

2521 Multisystemic inflammatory disease in Pheasantshell (Unionidae, Actinonaias pectorosa) associated with Yokenella regensburgei infection at sites experiencing seasonal mass mortality events

Gomes Da Silva Neto, J.; Hardman, R. H.; Engman, A. C.; Dinkins, G. R.; Lane, T.; Fry, M. M.; Rines, C. R.; Bisenieks, A.; Rajeev, S.; Dennis, M. M.

10.1101/2024.03.14.585088 — ecology — Posted on 2024-03-16

2522 Real-time TIRF imaging of single adiponectin vesicle exocytosis in 3T3-L1 adipocytes stably expressing mCherry fused to human adiponectin

Shrestha, M. M.; Barg, S.; Olofsson, C. S.

10.1101/2022.09.13.507762 — cell biology — Posted on 2024-03-16

2523 Construction and Application of a Technical Platform for Determining Cell Cycle- and Autophagy-Associated Cellular Uptake of Lipid-Based Nanoparticles

Wang, Y.; Luo, G.; Wang, H.; Zheng, Y.; Xu, X.; Zhou, W.; Lin, J.; Chen, B.; Sui, M.

10.1101/2024.02.19.579560 — cell biology — Posted on 2024-03-16

2524 Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation

Witt, L.; Greenfield, K.; Knoop, K.

10.1101/2023.10.02.560561 — immunology — Posted on 2024-03-16

2525 SYNAPTOTAGMIN-9 IN MOUSE RETINA

Mesnard, C. S.; Hays, C. L.; Townsend, L. E.; Barta, C. L.; Gurumurthy, C.; Thoreson, W. B.

10.1101/2023.06.27.546758 — neuroscience — Posted on 2024-03-16

2526 Taxonomy for human social perception

Santavirta, S.; Malen, T.; Erdemli, A.; Nummenmaa, L.

10.1101/2023.09.28.559888 — neuroscience — Posted on 2024-03-16

2527 Non-invasive optical synthetization of hearing sensation in non-genetically modified animal

Tamai, Y.; Uenaka, M.; Okamoto, A.; Hosokawa, K.; Ito, Y.; Toda, K.; Hiryu, S.; Kobayasi, K. I.

10.1101/2023.05.13.540641 — neuroscience — Posted on 2024-03-16

2528 LoCS-Net: Localizing Convolutional Spiking Neural Network for Fast Visual Place Recognition

Akcal, M. U.; Raikov, I. G.; Gribkova, E. D.; Choudhuri, A.; Soltesz, I.; Gillette, R.; Chowdhary, G.

10.1101/2024.03.14.584997 — neuroscience — Posted on 2024-03-16

2529 Surface temperatures are influenced by handling stress independently of corticosterone levels in wild king penguins (Aptenodytes patagonicus)

Lewden, A.; Ward, C.; Noiret, A.; Avril, S.; Abolivier, L.; Gerard, C.; Hammer, T. L.; Raymond, E.; Robin, J.-P.; Viblanc, V. A.; Bize, P.; STIER, A.

10.1101/2023.06.16.545254 — zoology — Posted on 2024-03-16

2530 The molecular basis of pine wilt disease resistance in Pinus massoniana

wang, j.; Cai, S.; Zeng, L.; Tong, J.; Hang, D.; Zhang, X.; Fang, Y.; Su, S.; SU, J.

10.1101/2024.03.13.584545 — plant biology — Posted on 2024-03-16

2531 Fast and recurrent evolution of temperature preference among drosophilids

Kafle, T.; Grub, M.; Sakagiannis, P.; Nawrot, M. P.; Arguello, J. R.

10.1101/2024.03.15.585210 — evolutionary biology — Posted on 2024-03-16

2532 Population structure and genetic diversity of the Critically Endangered bowmouth guitarfish (Rhina ancylostomus) in the Northwest Indian Ocean

Kipperman, M. J.; Jabado, R. W.; Haque, A. B.; Fernando, D.; Anjani, P. A. D. L.; Spaet, J. L.; Humble, E.

10.1101/2024.03.15.585225 — evolutionary biology — Posted on 2024-03-16

2533 Repatterning of mammalian backbone regionalization in cetaceans

Gillet, A.; Jones, K. E.; Pierce, S. E.

10.1101/2024.03.15.585285 — evolutionary biology — Posted on 2024-03-16

2534 FST and genetic diversity in an island model with background selection

Hasan, S. A.; Whitlock, M. C.

10.1101/2024.03.15.585154 — evolutionary biology — Posted on 2024-03-16

2535 Transcriptomic response to pyrethroid treatment in closely related bed bug strains varying in resistance

Haberkorn, C.; Belgaidi, Z.; Lasseur, R.; Vavre, F.; Varaldi, J.

10.1101/2024.03.15.584589 — evolutionary biology — Posted on 2024-03-16

2536 Global climate change effect on Asian Mus musculus; Implication from last glacial maximum to the end of the 21st century

Afzali, Y. A.

10.1101/2024.03.14.584992 — evolutionary biology — Posted on 2024-03-16

2537 Phylogeny-aware modeling uncovers molecular functional convergences associated with complex multicellularity in Eukarya

Pereira Lobo, F.; Benjamim da Costa, D.; Martins da Silva, T. T.; de Oliveira, M. D.

10.1101/2024.03.14.585020 — evolutionary biology — Posted on 2024-03-16

2538 First insights of the Danube sturgeon (Acipenser gueldenstaedtii) skin adherent microbiota

Matache, R.; Deak, G.; Jawdhari, A.; Sadica, I.; Pop, C.-E.; Fendrihan, S.; Craciun, N.

10.1101/2024.03.13.584882 — microbiology — Posted on 2024-03-16

2539 Impact of extracellular current flow on action potential propagation in myelinated axons

Abdollahi, N.; Prescott, S. A.

10.1101/2024.03.15.585219 — neuroscience — Posted on 2024-03-15

2540 Imputation of ancient canid genomes reveals inbreeding history over the past 10,000 years

10.1101/2024.03.15.585179 — evolutionary biology — Posted on 2024-03-15

2541 OCTOPUS: Disk-based, Multiplatform, Mobile-friendly Metagenomics Classifier

Marini, S.; Barquero, A.; Wadhwani, A. A.; Bian, J.; Ruiz, J.; Boucher, C.; Prosperi, M.

10.1101/2024.03.15.585215 — molecular biology — Posted on 2024-03-15

2542 Antagonistic behavior of brain networks mediated by low-frequency oscillations: electrophysiological dynamics during internal-external attention switching

Hammer, J.; Kajsova, M.; Kalina, A.; Krysl, D.; Fabera, P.; Kudr, M.; Jezdik, P.; Janca, R.; Krsek, P.; Marusic, P.

10.1101/2024.03.14.584984 — neuroscience — Posted on 2024-03-15

2543 Prenatal tuning of thalamic spontaneous activity patterns regulates somatosensory map resolution

Anibal-Martinez, M.; Puche-Aroca, L.; Pumo, G.; Vandael, D.; Madrigal, M. P.; Rodriguez-Malmierca, L. M.; Valdeolmillos, M.; Martini, F. J.; Rijli, F. M.; Lopez-Bendito, G.

10.1101/2024.03.15.585193 — neuroscience — Posted on 2024-03-15

2544 Phase separation of polyubiquitinated proteins in UBQLN2 condensates controls substrate fate

Valentino, I. M.; Llivicota-Guaman, J. G.; Dao, T. P.; Mulvey, E. O.; Lehman, A. M.; Galagedera, S. K. K.; Mallon, E. L.; Castaneda, C. A.; Kraut, D. A.

10.1101/2024.03.15.585243 — biochemistry — Posted on 2024-03-15

2545 Welding PROxAb Shuttles: A modular approach for generating bispecific antibodies via site-specific protein-protein conjugation

Lehmann, T.; Schneider, H.; Tonillo, J.; Schanz, J.; Schwarz, D.; Schroeter, C.; Kolmar, H.; Hecht, S.; Anderl, J.; Rasche, N.; Rieker, M.; Dickgiesser, S.

10.1101/2024.03.15.585232 — biochemistry — Posted on 2024-03-15

2546 Non-prime- and Prime-side Profiling of Pro-Pro Endopeptidase Specificity Using Synthetic Combinatorial Peptide Libraries and Mass Spectrometry

Claushuis, B.; Cordfunke, R. A.; de Ru, A. H.; van Angeren, J.; Baumann, U.; van Veelen, P. A.; Wuhrer, M.; Corver, J.; Drijfhout, J. W.; Hensbergen, P.

10.1101/2024.03.15.585006 — molecular biology — Posted on 2024-03-15

2547 BAK knockdown delays bleaching and alleviates oxidative DNA damage in a reef-building coral

Majerova, E.; Steinle, C.; Drury, C.

10.1101/2024.03.14.585106 — molecular biology — Posted on 2024-03-15

2548 Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and fitness effects

da Trindade, N. S.; Valentini, M. B.; Rognon, A.; Mendes, T. M. F.; Allegretti, S. M.; Grunau, C.; Cabral, F. J.

10.1101/2024.03.15.585160 — molecular biology — Posted on 2024-03-15

2549 Female-dominated disciplines have lower evaluated research quality and funding success rates, for men and women

James, A.; Buelow, F.; Gibson, L.; Brower, A.

10.1101/2024.03.14.585000 — scientific communication and education — Posted on 2024-03-15

2550 Protein Language Models Expose Viral Mimicryand Immune Escape

Ofer, D.; Linial, M.

10.1101/2024.03.14.585057 — bioinformatics — Posted on 2024-03-15

2551 Dissecting AlphaFolds Capabilities with Limited Sequence Information

Gut, J. A.; Lemmin, T.

10.1101/2024.03.14.585076 — bioinformatics — Posted on 2024-03-15

2552 MetagenomicKG: a knowledge graph for metagenomic applications

Ma, C.; Liu, S.; Koslicki, D.

10.1101/2024.03.14.585056 — bioinformatics — Posted on 2024-03-15

2553 Solvation Free Energy in Governing Equations for DNA Hybridization, Protein-Ligand Binding, and Protein Folding

Harmon, C.; Bui, A.; Espejo, J. M.; Gancayco, M.; Le, J. M.; Rangel, J.; Eggers, D. K.

10.1101/2024.03.15.585270 — biochemistry — Posted on 2024-03-15

2554 Revisiting the activity of two poly(vinyl chloride)- and polyethylene-degrading enzymes

Stepnov, A. A.; Lopez-Tavera, E.; Klauer, R.; Lincoln, C. L.; Chowreddy, R. R.; Beckham, G. T.; Eijsink, V. G. H.; Solomon, K.; Blenner, M.; Vaaje-Kolstad, G.

10.1101/2024.03.15.585159 — biochemistry — Posted on 2024-03-15

2555 R6G narrows BmrA conformational spectrum for a more efficient use of ATP

Gobet, A.; Moissonnier, L.; Zarkadas, E.; Magnard, S.; Bettler, E.; Martin, J.; Terreux, R.; Schoehn, G.; Orelle, C.; Jault, J.-M.; Falson, P.; Chaptal, v.

10.1101/2024.03.15.585201 — biochemistry — Posted on 2024-03-15

2556 Functional exploration of in vivo and in vitro lignocellulose-fed rumen bacterial microbiomes reveals novel enzymes involved in polysaccharide breakdown

Ufarte, L.; Laville, E.; Lazuka, A.; Lajus, S.; Bouhajja, E.; Cecchini, D.; Rizzo, A.; Amblard, E.; Drula, E.; Lombard, V.; Terrapon, N.; Henrissat, B.; Cleret, M.; Morgavi, D. P.; Dumon, C.; Robe, P.; Klopp, C.; Bozonnet, S.; Hernandez-Raquet, G.; Potocki-Veronese, G.

10.1101/2024.03.15.585145 — biochemistry — Posted on 2024-03-15

2557 Biochemical analysis of the endoribonuclease activity of the human mitochondrial topoisomerase 1

Bader, C. P. J.; Kasho, E.; Forslund, J. M. E.; Wessels, M.; Wanrooij, P. H.

10.1101/2024.03.15.585299 — biochemistry — Posted on 2024-03-15

2558 14-3-3 binding regulates Tau assembly and microtubule association.

Hochmair, J.; van den Oetelaar, M. C. M.; Diez, L.; Lemmens, L. J. M.; Ponce, R.; Ravatt, L.; Franck, M. W.; Semenova, E.; Mohapatra, S.; Ottmann, C. O.; Brunsveld, L.; Wegmann, S.

10.1101/2024.03.15.585148 — biochemistry — Posted on 2024-03-15

2559 Undruggable oncoproteins cMyc and NMyc bind to mediator of transcription with superior high affinity

Knight, A.; Houser, J.; Otasevic, T.; Juran, V.; Vybihal, V.; Smrcka, M.; martin, D.

10.1101/2024.03.15.585150 — biochemistry — Posted on 2024-03-15

2560 Lysine-Cysteine-Serine-Tryptophan Inserted into the DNA-Binding Domain of Human Mineralocorticoid Receptor Increases Transcriptional Activation by Aldosterone

Katsu, Y.; Zhang, J.; Baker, M. E.

10.1101/2024.03.14.585051 — evolutionary biology — Posted on 2024-03-15

2561 Emergent time scales of epistasis in protein evolution

Di Bari, L.; Bisardi, M.; Cotogno, S.; Weigt, M.; Zamponi, F.

10.1101/2024.03.14.585034 — evolutionary biology — Posted on 2024-03-15

2562 Crosstalk of the MAP3K1 and EGFR pathways mediates gene-environment interactions that disrupt developmental tissue closure

Wang, J.; Xiao, B.; Kimura, E.; Mongan, M.; Hsu, W.-w.; Medvedovic, M.; Puga, A.; Xia, Y.

10.1101/2024.03.14.585101 — developmental biology — Posted on 2024-03-15

2563 Measuring integrin force loading rates using a two-step DNA tension sensor

Combs, J. D.; Foote, A. K.; Ogasawara, H.; Velusamy, A.; Rashid, S. A.; Mancuso, J. N.; Salaita, K.

10.1101/2024.03.15.585042 — cell biology — Posted on 2024-03-15

2564 asteRIa enables robust interaction modeling between chromatin modifications and epigenetic readers

Stadler, M.; Lukauskas, S.; Bartke, T.; Mueller, C. L.

10.1101/2024.03.15.585146 — molecular biology — Posted on 2024-03-15

2565 ADMA-histones define genomic loading of Rhino at the initial step of piRNA cluster formation

Saito, R.; Ishizu, H.; Harigai, R.; Murano, K.; Siomi, M. C.

10.1101/2024.03.15.585151 — molecular biology — Posted on 2024-03-15

2566 Erosion of X-Chromosome Inactivation in female hiPSCs is heterogeneous and persists during differentiation

Raposo, A. C.; Caldas, P.; Arez, M.; Jeremias, J.; Barbosa, P.; Sousa-Luis, R.; Agua, F. D.; Oxley, D.; Mupo, A. M.; Eckersley-Maslin, M.; Casanova, M.; Grosso, A. R.; da Rocha, S. T.

10.1101/2024.03.15.585169 — molecular biology — Posted on 2024-03-15

2567 Transcription of damage-induced RNA in Arabidopsis was frequently initiated from DSB loci within the genic regions

Kawaguchi, K.; Satoh, S.; Obokata, J.

10.1101/2024.03.15.585142 — molecular biology — Posted on 2024-03-15

2568 Advancing microbial isolation: The impact of leaf mold extract agar on soil samples

Miyashita, A.; Mikami, K.; Ishii, M.; Miyauchi, M.; Tabuchi, F.

10.1101/2024.03.15.585253 — microbiology — Posted on 2024-03-15

2569 N-acyl homoserine lactone signaling modulates bacterial community associated with human dental plaque

Sikdar, R.; Beauclaire, M. V.; Lima, B. P.; Herzberg, M. C.; Elias, M. H.

10.1101/2024.03.15.585217 — microbiology — Posted on 2024-03-15

2570 A Preliminary list of Birds from Laguna de Matusagarati: A Wildlife Refuge in Darien Province, Panama

Garzon, J. L.; Pimentel, G.; Carrera, J. P.; Valderrama, A.; Alfaro, Y.; Medina, J. L.; Castillero, P.

10.1101/2024.03.14.585043 — zoology — Posted on 2024-03-15

2571 Late Miocene transformation of Mediterranean Sea biodiversity

Agiadi, K.; Hohmann, N.; Gliozzi, E.; Thivaiou, D.; Bosellini, F.; Taviani, M.; Bianucci, G.; Collareta, A.; Londeix, L.; Faranda, C.; Bulian, F.; Koskeridou, E.; Lozar, F.; Mancini, A. M.; Dominici, S.; Moissette, P.; Campos, I. B.; Borghi, E.; Iliopoulos, G.; Antonarakou, A.; Kontakiotis, G.; Besiou, E.; Zarkogiannis, S. D.; Harzhauser, M.; Sierro, F. J.; Coll, M.; Vasiliev, I.; Camerlenghi, A.; Garcia-Castellanos, D.

10.1101/2024.03.14.585031 — paleontology — Posted on 2024-03-15

2572 Data Imbalance in Drug Response Prediction - Multi-Objective Optimization Approach in Deep Learning Setting

Narykov, O.; Zhu, Y.; Brettin, T.; Evrard, Y. A.; Partin, A.; Xia, F.; Shukla, M.; Vasanthakumari, P.; Doroshow, J. H.; Stevens, R. L.

10.1101/2024.03.14.585074 — cancer biology — Posted on 2024-03-15

2573 Single cell view of tumor microenvironment gradients in pleural mesothelioma

Giotti, B.; Dolasia, K.; Zhao, w.; Cai, P.; Sweeney, R.; Merritt, E.; Kiner, E.; Kim, G.; Bhagwat, A.; Hegde, S.; Fitzgerald, B.; Shroff, S.; Dawson, T.; Garcia-Barros, M.; Abdul-Ghafar, J.; Chen, R.; Gnjatic, S.; Soto, A.; Brody, R.; Kim-Schulze, S.; Chen, Z.; Beaumont, K. G.; Merad, M.; Flores, R.; Sebra, R.; horowitz, a.; Marron, T. U.; Tocheva, A.; Wolf, A.; Tsankov, A.

10.1101/2024.03.14.585048 — cancer biology — Posted on 2024-03-15

2574 Hour-long, kilohertz sampling rate 3D single-virus tracking in live cells enabled by StayGold fluorescent protein fusions

Lin, Y.; Exell, J.; Lin, H.; Zhang, C.; Welsher, K. D.

10.1101/2024.03.14.585070 — biophysics — Posted on 2024-03-15

2575 Optimizing Design of Genomics Studies for Clonal Evolution Analysis

Srivatsa, A.; Schwartz, R.

10.1101/2024.03.14.585055 — bioinformatics — Posted on 2024-03-15

2576 Transcription factor prediction using protein 3D structures

Neuhaus, F.; Liebold, J.; Baumbach, J.; Newaz, K.

10.1101/2024.03.14.585054 — bioinformatics — Posted on 2024-03-15

2577 WISH-BONE: Whole-mount In Situ Histology, to label osteocyte mRNA and protein in 3D adult mouse bones

Meslier, Q. A.; Duerr, T. J.; Nguyen, B.; Monaghan, J. R.; Shefelbine, S. J.

10.1101/2024.03.14.585053 — bioengineering — Posted on 2024-03-15

2578 SegmentNT: annotating the genome at single-nucleotide resolution with DNA foundation models

de Almeida, B. P.; Dalla-Torre, H.; Richard, G.; Blum, C.; Hexemer, L.; Gelard, M.; Pandey, P.; Laurent, S.; Laterre, A.; Lang, M.; Sahin, U.; Beguir, K.; Pierrot, T.

10.1101/2024.03.14.584712 — genomics — Posted on 2024-03-15

2579 Olfaction in Tephritidae: a balance between detection and discrimination

Ramiaranjatovo, G.; Charlery de la Masseliere, M.; Dekker, T.; Duyck, P.-F.; Larsson Herrera, S.; Reynaud, B.; Jacob, V.

10.1101/2024.03.14.584788 — ecology — Posted on 2024-03-15

2580 Generation of densely labeled oligonucleotides for the detection of small genomic elements

Steinek, C.; Guirao Ortiz, M.; Stumberger, G.; Toelke, A. J.; Hoerl, D.; Carell, T.; Harz, H.; Leonhardt, H.

10.1101/2024.03.15.583980 — cell biology — Posted on 2024-03-15

2581 Epidemiological, Serological, and Virological Analysis of an Outbreak of Elephant Hemorrhagic Disease in Switzerland

Ackermann, M.; Kubacki, J.; Heaggans-Ebbeson, S.; Hayward, G. S.; Lechmann, J.

10.1101/2024.03.14.585086 — microbiology — Posted on 2024-03-15

2582 Comprehensive non-black box classification of highly correlated ecological time series pairs containing many zeros: the case of gut microbiome of mice

Maskawa, R.; Takayasu, H.; Islam, T.; Takayasu, L.; Kurokawa, R.; Masuoka, H.; Suda, W.; Takayasu, M.

10.1101/2024.03.15.585153 — microbiology — Posted on 2024-03-15

2583 Bradyrhizobium and the soybean rhizosphere: Species level bacterial population dynamics in established soybean fields, rhizosphere and nodules.

Sarao, S. K.; Boothe, V.; Das, B. K.; Gonzalez Hernandez, J. L.; Brozel, V. S.

10.1101/2024.03.15.585214 — microbiology — Posted on 2024-03-15

2584 A functional circadian clock regulates composition and daily bacterial load of the gut microbiome in Drosophila melanogaster

Battistolli, M.; Varponi, I.; Romoli, O.; Sandrelli, F.

10.1101/2024.03.15.585158 — microbiology — Posted on 2024-03-15

2585 Common soil history is more important than plant history for arbuscular mycorrhizal community assembly in an experimental grassland diversity gradient

Albracht, C.; Solbach, M. D.; Hennecke, J.; Bassi, L.; van der Ploeg, G. R.; Eisenhauer, N.; Weigelt, A.; Buscot, F.; Heintz-Buschart, A.

10.1101/2024.03.14.585138 — microbiology — Posted on 2024-03-15

2586 The Toxoplasma gondii mitochondrial transporter ABCB7 is essential for cytosolic iron-sulfur cluster biogenesis and protein translation

Maclean, A. E.; Sloan, M. A.; Renaud, E. A.; Demolombe, V.; Besteiro, S.; Sheiner, L.

10.1101/2024.03.15.585200 — microbiology — Posted on 2024-03-15

2587 Clostridium innocuum, an opportunistic gut pathogen, inactivates host gut progesterone and arrests ovarian follicular development

Chen, M.-J.; Chou, C.-H.; Hsiao, T.-H.; Wu, T.-Y.; Li, C.-Y.; Chen, Y.-L.; Chao, K.-H.; Lee, T.-H.; Gicana, R.; Shih, C.-J.; Brandon-Mong, G.-J.; Lai, Y.-L.; Li, P.-T.; Tseng, Y.-L.; Wang, P.-H.; Chiang, Y.-R.

10.1101/2024.03.15.585140 — microbiology — Posted on 2024-03-15

2588 Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

Luo, X.; McAndrews, K. M.; Arian, K. A.; Morse, S. J.; Boeker, V.; Kumbhar, S. V.; Hu, Y.; Mahadevan, K. K.; Church, K. A.; Chitta, S.; Ryujin, N. T.; Hensel, J.; Dai, J.; Dowlatshahi, D. P.; Sugimoto, H.; Kirtley, M. L.; LeBleu, V. S.; Shalapour, S.; Simmons, J. H.; Kalluri, R.

10.1101/2024.03.14.585062 — immunology — Posted on 2024-03-15

2589 Overlapping roles of Arabidopsis INCURVATA11 and CUPULIFORMIS2 as Polycomb Repressive Complex 2 accessory proteins

Nadi, R.; Juan-Vicente, L.; Lup, S. D.; Fernandez, Y.; Rubio, V.; Micol, J. L.

10.1101/2024.03.15.585069 — plant biology — Posted on 2024-03-15

2590 Protein-based cell population discovery and annotation for CITE-seq data identifies cellular phenotypes associated with critical COVID-19 severity

Allen, D.; Weaver, M.; Prokopchuk, S.; Lekschas, F.; Jiang, M.; Finak, G.; Greene, E.; McDavid, A.

10.1101/2024.03.14.584720 — bioinformatics — Posted on 2024-03-15

2591 Differential Patterns of Cross-Protection against Antigenically Distinct Variants in Small Animal Models of SARS-CoV-2 Infection

Selvaraj, P.; Stauft, C. B.; Liu, S.; Sangare, K.; Wang, T. T.

10.1101/2024.03.14.584985 — microbiology — Posted on 2024-03-15

2592 An expanded genetic toolkit for inducible expression and targeted gene silencing in Rickettsia parkeri

McGinn, J.; Wen, A.; Edwards, D. L.; Brinkley, D. M.; Lamason, R. L.

10.1101/2024.03.15.585227 — microbiology — Posted on 2024-03-15

2593 ONE HEALTH APPROACH ON SARS-COV-2 - USING SHEEP AS SENTINEL ANIMALS TO INCREASE FUTURE PANDEMIC PREPAREDNESS - a pilot study

Samojlovic, M.; Mesquita, J.; Santos-Silva, S.; Neptin, M.; Esbjornsson, J.

10.1101/2024.03.15.585163 — microbiology — Posted on 2024-03-15

2594 de Novo Sequencing of Antibodies for Identification of Neutralizing Antibodies in Human Plasma Post SARS-CoV-2 Vaccination

Le Bihan, T.; Nunez de Villavicencio Diaz, T.; Reitzel, C.; Lange, V.; Park, M.; Beadle, E. M.; Wu, L.; Jovic, M.; Dubois, R. M.; Couzens, A. L.; Duan, J.; Han, X.; Liu, Q.; Ma, B.

10.1101/2024.03.14.583523 — immunology — Posted on 2024-03-15

2595 Simultaneous and Dynamic Super-Resolution Imaging of Two Proteins in Arabidopsis thaliana using dual-color sptPALM

Rohr, L.; Ehinger, A.; Burmeister, N. G.; Meixner, A. J.; Kemmerling, B.; Harter, K.; zur Oven-Krockhaus, S.

10.1101/2024.03.13.584811 — plant biology — Posted on 2024-03-15

2596 Predicting absolute protein folding stability using generative models

Cagiada, M.; Ovchinnikov, S.; Lindorff-Larsen, K.

10.1101/2024.03.14.584940 — biophysics — Posted on 2024-03-15

2597 Construction of an Immunoinformatics-Based Multi-Epitope Vaccine Candidate targeting Kyasanur Forest Disease Virus

Manjari, S.; Rajan, L. S.; Shete, A. M.; Jani, V.; Patil, S.; Joshi, Y.; Sahay, R. R.; Patil, D. Y.; Mohandas, S.; Majumdar, T.; Sonavane, U.; Joshi, R.; Yadav, P.

10.1101/2024.03.14.584963 — bioinformatics — Posted on 2024-03-15

2598 Pandora: A Tool to Estimate Dimensionality Reduction Stability of Genotype Data

Haag, J.; Jordan, A. I.; Stamatakis, A.

10.1101/2024.03.14.584962 — bioinformatics — Posted on 2024-03-15

2599 Comparison of Single-cell Long-read and Short-read Transcriptome Sequencing of Patient-derived Organoid Cells of ccRCC: Quality Evaluation of the MAS-ISO-seq Approach

Zajac, N.; Zhang, Q.; Bratus-Neuenschwander, A.; Qi, W.; Bolck, H. A.; Karakulak, T.; Carrasco Oltra, T.; Moch, H.; Kahraman, A.; Rehrauer, H.

10.1101/2024.03.14.584953 — genomics — Posted on 2024-03-15

2600 Arrayed CRISPRi library to suppress genes required for Schizosaccharomyces pombe viability

Ishikawa, K.; Soejima, S.; Nishimura, T.; Saitoh, S.

10.1101/2024.03.14.584550 — cell biology — Posted on 2024-03-15

2601 Dynamic fibroblast-immune interactions shape wound healing after brain injury

Ewing-Crystal, N. A.; Mroz, N. M.; Chang, A. A.; Merrill, E. D.; Caryotakis, S. E.; Teo, L.; Larpthaveesarp, A.; Tsukui, T.; Katewa, A.; Pennington, R.; McKinsey, G. L.; Nelson, S.; Ciesielska, A.; Dahlgren, M. W.; Paidassi, H.; Jain, S.; Aghi, M. K.; Bourne, J. A.; Paz, J. T.; Gonzalez, F. F.; Sheppard, D.; Molofsky, A. V.; Arnold, T. D.; Molofsky, A. B.

10.1101/2024.03.13.584873 — immunology — Posted on 2024-03-15

2602 A hemagglutinin and neuraminidase biased immunological memory shapes the dynamics of antibody responses to Influenza A virus

Lin, X.; Wang, J.; Ling, S.; Xiao, C.; Liang, Z.; Chow, C. L.; Yang, B.; Xiao, B.; Cowling, B. J.; Webby, R. J.; Zanin, M.; Wong, S.-S.

10.1101/2024.03.14.584765 — immunology — Posted on 2024-03-15

2603 A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling

Curren, B.; Ahmed, T.; Rashid, R. B.; Sebina, I.; Sikder, M. A. A.; Howard, D. R.; Alorro, M.; Ullah, M. A.; Bissell, A.; Rahman, M. M.; Pearen, M. A.; Ramm, G. A.; Varelias, A.; Rose-John, S.; Cuiv, P. O.; Spann, K. M.; Dennis, P. G.; Phipps, S.

10.1101/2024.03.13.584927 — immunology — Posted on 2024-03-15

2604 Effects of Feed Processing Type, Protein Source, and Environmental Salinity on Litopenaeus vannamei Feeding Behaviour

Moss, A. S.; Brooker, A. J.; Ozioko, S.; Nederlof, M.; Debnath, S.; Schrama, J.

10.1101/2024.03.14.584959 — zoology — Posted on 2024-03-15

2605 Time series-free rhythm profiling using COFE reveals multi-omic circadian rhythms in in-vivo human cancers

Ananthasubramaniam, B.; Venkataramanan, R.

10.1101/2024.03.13.584582 — systems biology — Posted on 2024-03-15

2606 Defining network topologies that can achieve molecular memory

Sevlever, F.

10.1101/2024.03.13.584853 — systems biology — Posted on 2024-03-15

2607 A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype

Söderqvist, S. I. M.; Viljamaa, A.; Geyer, N.; Strell, C.; Hekmati, N.; Engstrand, J.; Sparrelid, E.; Salmen, C.; Heuchel, R. L.; Zacharouli, A.; Ghorbani, P.; Harrizi, S.; Hamidi, Y.; Khorosjutina, O.; Milanova, S.; Schmierer, B.; Bozoky, B.; Moro, C. F.; Gerling, M.

10.1101/2024.03.14.584614 — cancer biology — Posted on 2024-03-15

2608 Metabolic Reprogramming by Mutant GNAS Creates an Actionable Dependency in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Makino, Y.; Rajapakshe, K. I.; Selvanesan, B. C.; Okumura, T.; Date, K.; Dutta, P.; Abou-Elkacem, L.; Sagara, A.; Min, J.; Sans, M.; Yee, N.; Siemann, M. J.; Enriquez, J.; Smith, P.; Bhattacharya, P.; Kim, M.; Dede, M.; Hart, T.; Maitra, A.; Thege, F. I.

10.1101/2024.03.13.584524 — cancer biology — Posted on 2024-03-15

2609 A physically inspired approach to coarse-graining transcriptomes reveals the dynamics of aging: multiscale description of gene expressions and a spectral view of aging dynamics

Li, T.; Mani, M.

10.1101/2024.03.13.584889 — biophysics — Posted on 2024-03-15

2610 Proofreading and single-molecule sensitivity in T-cellreceptor signaling by condensate nucleation

White, W. L.; Baker, D.; Groves, J. T.; Baker, D.; Ben-sasson, A. J.; Kueh, H. Y.

10.1101/2024.03.13.584745 — biophysics — Posted on 2024-03-15

2611 Molecular Insights into the Rescue Mechanism of an hERG Activator Against Severe LQT2 Mutations.

Kumawat, A.; Tavazzani, E.; Lentini, G.; Trancuccio, A.; Kukavica, D.; Denegri, M.; Priori, S. G.; Camilloni, C.

10.1101/2024.03.13.584147 — biophysics — Posted on 2024-03-15

2612 How motility drives the glassy dynamics in confluent epithelial monolayers?

Sadhukhan, S.; Nandi, M. K.; Pandey, S.; Paoluzzi, M.; Dasgupta, C.; Gov, N.; Nandi, S. K.

10.1101/2024.03.14.584932 — biophysics — Posted on 2024-03-15

2613 Lipophilic compounds restore wt function of neurodevelopmental-associated KCNQ3 mutations.

Edmond, M. A.; Hinojo-Perez, A.; Efrem, M.; Lin, Y.-C.; Shams, I.; Hayoz, S.; de la Cruz, A.; rodriguez, M. E. P.; Diaz-Solares, M.; Dykxhoorn, D. M.; Luo, Y.; Soria, R. B.

10.1101/2024.03.13.584879 — biophysics — Posted on 2024-03-15

2614 ProAffinity-GNN: A Novel Approach to Structure-based Protein-Protein Binding Affinity Prediction via a Curated Dataset and Graph Neural Networks

Zhou, Z.; Yin, Y.; Han, H.; Jia, Y.; Koh, J. H.; Kong, A. W.-k.; Mu, Y.

10.1101/2024.03.14.584935 — bioinformatics — Posted on 2024-03-15

2615 Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight

Nourbakhsh, M.; Zheng, Y.; Noor, H.; Tiberti, M.; Gevaert, O.; Papaleo, E.

10.1101/2024.03.14.584946 — bioinformatics — Posted on 2024-03-15

2616 A sensorimotor enhanced neuromusculoskeletal model for simulating postural control of upright standing

Shanbhag, J.; Fleischmann, S.; Wechsler, I.; Gassner, H.; Winkler, J.; Eskofier, B. M.; Koelewijn, A. D.; Wartzack, S.; Miehling, J.

10.1101/2024.03.13.584822 — bioengineering — Posted on 2024-03-15

2617 Intra-Lymph Node Crosslinking of Antigen-Bearing Polymers Enhances Humoral Immunity and Dendritic Cell Activation

Euliano, E. M.; Agrawal, A.; Yu, M. H.; Graf, T. P.; Henrich, E. M.; Kunkel, A. A.; McHugh, K. J.

10.1101/2024.03.13.584831 — bioengineering — Posted on 2024-03-15

2618 Modeling the impact of optimized airflow and sick pen management on the spread of infectious diseases in swine barns

Safari, M.; Fleming, C.; Galvis, J. A.; Deka, A.; Sanchez, F.; Machado, G.; Yeh, C.-A.

10.1101/2024.03.13.584486 — bioengineering — Posted on 2024-03-15

2619 Development of a novel GWAS method to detect QTL effects interacting with the discrete and continuous population structure

Hamazaki, K.; Iwata, H.; Mary-Huard, T.

10.1101/2024.03.13.584913 — genomics — Posted on 2024-03-15

2620 Insights Into Ribosomal DNA (rDNA) Dominance and Magnification Through Characterization of Isogenic Deletion Alleles

Kindelay, S. M.; Maggert, K. A.

10.1101/2024.03.13.584845 — genetics — Posted on 2024-03-15

2621 Identification of candidate causal cis-regulatory variants underlying electrocardiographic QT interval GWAS loci

Kapoor, A.

10.1101/2024.03.13.584880 — genetics — Posted on 2024-03-15

2622 Haplore: An alternative approach for Y chromosomal haplogroup identification

Laoprapaipan, L.; Phusawang, K.; Laorchairangsi, P.; Kitnitchee, A.; Wachirawanitchkit, H.; Suwanparsert, B.; Promnun, P.

10.1101/2024.03.13.584919 — evolutionary biology — Posted on 2024-03-15

2623 The host genotype actively shapes its microbiome across generations

Benga, L.; Rehm, A.; Gougoula, C.; Westhoff, P.; Wachtmeister, T.; Benten, W. P. M.; Engelhardt, E.; Weber, A. P. M.; Koehrer, K.; Sager, M.; Janssen, S.

10.1101/2024.03.14.584950 — ecology — Posted on 2024-03-15

2624 Rust Fungus Red Data List and Census Catalogue for Wales

Woods, R. G.; Stringer, R. N.; Evans, D. A.; Chater, A. O.

10.1101/2024.03.13.582811 — microbiology — Posted on 2024-03-15

2625 A regulatory B cell subpopulation expressing CD301b lectin promotes breast cancer growth

Paschall, A. V.; Nawaz, Z.; Avci, F.

10.1101/2024.03.13.584829 — immunology — Posted on 2024-03-15

2626 Divergent effects of C4a, C4adesArg, and thrombin on platelet aggregation and phosphorylation of ERK and Akt in human endothelial cells.

Liu, M.; Luu, V. K. T.; Wang, h.

10.1101/2024.03.13.584877 — immunology — Posted on 2024-03-15

2627 A rapid and efficient in vivo inoculation method for introducing tree stem canker pathogens onto leaves, suitable for large-scale assessment of resistance in poplar breeding progeny

li, z.; Zhang, B.; Fu, Y.; Suo, Y.; Zhang, Y.; Feng, J.; Pan, L.; Shen, W.; Liu, H.; Su, X.; Zhao, J.

10.1101/2024.03.13.584916 — plant biology — Posted on 2024-03-15

2628 CAR T cell infiltration and cytotoxic killing within the core of 3D breast cancer spheroids under control of antigen sensing in microwell arrays

Cho, Y.; Laird, M.; Bishop, T.; Li, R.; Ruffo, E.; Lohmueller, J.; Zervantonakis, I. K.

10.1101/2024.03.14.585033 — bioengineering — Posted on 2024-03-15

2629 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion

Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C. R.

10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-15

2630 SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion

Zhang, J.; Kennedy, A.; de Melo Jorge, D. M.; Xing, L.; Reid, W.; Bui, S.; Joppich, J.; Rose, M.; Ercan, S.; Tang, Q.; Tai, A. W.; Wang, Y.

10.1101/2022.03.04.483074 — cell biology — Posted on 2024-03-15

2631 HiTaC: a hierarchical taxonomic classifier for fungal ITS sequences compatible with QIIME2

Miranda, F. M.; Azevedo, V. A. C.; Ramos, R. T. J.; Renard, B. Y.; C. Piro, V.

10.1101/2020.04.24.014852 — bioinformatics — Posted on 2024-03-15

2632 Experience reduces route selection on conspecifics by the collectively migrating white stork

Bronnvik, H.; Nourani, E.; Fiedler, W.; Flack, A.

10.1101/2023.11.21.567993 — animal behavior and cognition — Posted on 2024-03-15

2633 Spaceflight causes strain-dependent gene expression changes associated with lipid and extracellular matrix dysregulation in the mouse kidney in vivo

Finch, R. H.; Vitry, G.; Siew, K.; Walsh, S. B.; Beheshti, A.; Hardiman, G.; da Silveira, W. A.

10.1101/2024.03.13.584781 — genomics — Posted on 2024-03-15

2634 Deep super-resolution imaging of thick tissue using structured illumination with adaptive optics

Wang, J.; Stoychev, D.; Phillips, M.; Pinto, D. M. S.; Parton, R. M.; Hall, N.; Titlow, J.; Faria, A. R.; Wincott, M.; Gala, D.; Gerondopoulos, A.; Irani, N.; Dobbie, I.; Schermelleh, L.; Booth, M.; Davis, I.

10.1101/2023.12.21.572818 — cell biology — Posted on 2024-03-15

2635 Performance of localization prediction algorithms decreases rapidly with the evolutionary distance to the training set increasing

Gould, S. B.; Magiera, J.; Garcia Garcia, C.; Raval, P. K.

10.1101/2023.12.18.572050 — cell biology — Posted on 2024-03-15

2636 Sensory choices as logistic classification

Carandini, M.

10.1101/2024.01.17.576029 — neuroscience — Posted on 2024-03-15

2637 Dynamic Network Analysis of Electrophysiological Task Data

Gohil, C.; Kohl, O.; Huang, R.; van Es, M. W. J.; Parker Jones, O.; Hunt, L. T.; Quinn, A. J.; Woolrich, M. W.

10.1101/2024.01.12.567026 — neuroscience — Posted on 2024-03-15

2638 The Neuron-specific IIS/FOXO Transcriptome in Aged Animals Reveals Regulatory Mechanisms of Neuronal and Cognitive Aging

Weng, Y.; Zhou, S.; Morillo, K.; Kaletsky, R.; Lin, S.; Murphy, C.

10.1101/2023.07.28.550894 — neuroscience — Posted on 2024-03-15

2639 Intracellular mechanical fingerprint reveals cell type specific mechanical tuning

Muenker, T. M.; Vos, B. E.; Betz, T.

10.1101/2023.08.10.552769 — biophysics — Posted on 2024-03-15

2640 Non-Gaussian Normative Modelling With Hierarchical Bayesian Regression

de Boer, S. A. A.; Bayer, J.; Kia, S. M.; Rutherford, S.; Zabihi, M.; Fraza, C.; Barkema, P.; Westlye, L. T.; Andreassen, O.; Hinne, M.; Beckmann, C. F.; Marquand, A. F.

10.1101/2022.10.05.510988 — neuroscience — Posted on 2024-03-15

2641 Early parafoveal semantic integration in natural reading

Pan, Y.; Frisson, S.; Federmeier, K. D.; Jensen, O.

10.1101/2022.09.26.509511 — neuroscience — Posted on 2024-03-15

2642 Comparing physiological impacts of positive pressure ventilation versus self-breathing via a versatile cardiopulmonary model incorporating a novel alveoli opening mechanism

Cabeleira, M. T.; Dharmalingam, V. A.; Black, C.; Ray, S.; Ovenden, N.; Diaz, V.

10.1101/2024.03.12.584596 — physiology — Posted on 2024-03-15

2643 Genome sequences of four Ixodes species expands understanding of tick evolution

Cerqueira de Araujo, A.; Noel, B.; Bretaudeau, A.; Labadie, K.; Boudet, M.; Tadrent, N.; Istace, B.; Kritli, S.; Cruaud, C.; Olaso, R.; Deleuze, J.-F.; Voordouw, M.; Hervet, C.; Plantard, O.; Zamoto-Niikura, A.; Chertemps, T.; Maibeche, M.; Hilliou, F.; Le Goff, G.; Kopacek, P.; Perner, J.; Chmelar, J.; Mazak, V.; Jmel, M. A.; Kotsyfakis, M.; Medina, J. M.; Hackenberg, M.; Simo, L.; Koutroumpa, F. A.; Wincker, P.; Aury, J.-M.; Rispe, C.

10.1101/2024.02.29.581698 — genomics — Posted on 2024-03-15

2644 Socioecological drivers of injuries in female and male rhesus macaques (Macaca mulatta)

Pavez Fox, M. A.; Siracusa, E.; Ellis, S.; Kimock, C.; Rivera-Barreto, N.; Negron-Del Valle, J.; Phillips, D.; Ruiz-Lambides, A.; Snyder-Mackler, N.; Higham, J.; Brent, L.; De Moor, D.

10.1101/2023.10.20.563310 — evolutionary biology — Posted on 2024-03-15

2645 Disentangling the effects of eutrophication and natural variability on macrobenthic communities across French coastal lagoons

Jones, A. G.; Schaal, G.; Boye, A.; Creemers, M.; Derolez, V.; Desroy, N.; Fiandrino, A.; Mouton, T. L.; Simier, M.; Smith, N.; Ouisse, V.

10.1101/2022.08.18.504439 — ecology — Posted on 2024-03-15

2646 Dynamic conformational changes of acid-sensing ion channels in different desensitizing conditions

Marcher Holm, C.; Topaktas, A. B.; Dannesboe, J.; Pless, S. A.; Heusser, S. A.

10.1101/2023.12.21.572759 — molecular biology — Posted on 2024-03-15

2647 Unveiling genome plasticity and a novel phage in Mycoplasma felis: Genomic investigations of four feline isolates

Klose, S. M.; Legione, A. R.; Bushell, R. N.; Browning, G. F.; Vaz, P. K.

10.1101/2023.12.16.572022 — microbiology — Posted on 2024-03-15

2648 A Data-Driven Latent Variable Approach to Validating the Research Domain Criteria Framework

Quah, S. K. L.; Jo, B.; Geniesse, C.; Uddin, L. Q.; Mumford, J. A.; Barch, D. M.; Fair, D. A.; Gotlib, I. H.; Poldrack, R. A.; Saggar, M.

10.1101/2024.01.31.577486 — neuroscience — Posted on 2024-03-15

2649 Stimulation of VTA dopamine inputs to LH upregulates orexin neuronal activity in a DRD2-dependent manner

Harada, M.; Capdevila, L. S.; Wilhelm, M.; Burdakov, D.; Patriarchi, T.

10.1101/2023.06.13.544720 — neuroscience — Posted on 2024-03-15

2650 A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in C. elegans

Binti, S.; Linder, A. G.; Edeen, P. T.; Fay, D. S.

10.1101/2024.03.12.584557 — genetics — Posted on 2024-03-15

2651 In sickness and in health: RNA-Seq finds viruses associated with mutualist quality in the Amazonian plant-ant Allomerus octoarticulatus

Tocora, M. C.; Reid, C.; Huisken, J.; Xue, H.; Frederickson, M. E.

10.1101/2024.03.12.583798 — ecology — Posted on 2024-03-15

2652 Transdifferentiation of fibroblasts into muscle cells to constitute cultured meat with tunable intramuscular fat deposition

Ma, T.; Ren, R.; Lv, J.; Yang, R.; Zheng, X.; Hu, Y.; Zhu, G.; Wang, H.

10.1101/2023.10.26.564179 — cell biology — Posted on 2024-03-15

2653 Systematic mutagenesis assay promotes comprehension of the strand-bias laws for mutations induced by oxidative DNA damage

Kawai, H.; Ebi, S.; Sugihara, R.; Fujiwara, C.; Fujikawa, Y.; Kimura, S.; Kamiya, H.

10.1101/2024.02.29.581290 — cell biology — Posted on 2024-03-15

2654 Heparan sulfate dependent phase separation of CCL5 and its chemotactic activity

Yu, X.; Duan, G.; Pei, P.; Chen, L.; Gu, R.; Hu, W.; Zhang, H.; Wang, Y.-D.; Gong, L.; Liu, L.; Chu, T.-T.; Li, J.-P.; Luo, S.-Z.

10.1101/2023.11.15.567182 — cell biology — Posted on 2024-03-15

2655 Microbial nitrogen guilds in the oceans: from the bathypelagic to the ocean surface

Rivas-Santisteban, J.; Fernandez-Gonzalez, N.; Laso-Perez, R.; Tamames, J.; Pedros-Alio, C.

10.1101/2024.03.05.583471 — microbiology — Posted on 2024-03-15

2656 Memory reactivation during sleep does not act holistically on object memory

Siefert, E. M.; Uppuluri, S.; Mu, J.; Tandoc, M. C.; Antony, J. W.; Schapiro, A. C.

10.1101/2023.12.14.571683 — neuroscience — Posted on 2024-03-15

2657 Coupling of saccade plans to endogenous attention during urgent choices

Goldstein, A. T.; Stanford, T. R.; Salinas, E.

10.1101/2024.03.01.583058 — neuroscience — Posted on 2024-03-15

2658 The Lifespan Trajectories of Brain Activities Related to Cognitive Control

Yang, G.; Li, Z.; Petersen, I. T.; Wang, L.; Radua, J.; Liu, X.

10.1101/2023.08.20.554018 — neuroscience — Posted on 2024-03-15

2659 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury

Eisdorfer, J. T.; Thackray, J. K.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Ruven, C.; Bohic, M.; Pusuloori, S.; Zmoyro, L.; Kumar, S.; Abraira Lab Computational Group, ; Schachner, M.; Sahni, V.; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.

10.1101/2023.10.31.564826 — neuroscience — Posted on 2024-03-15

2660 Group-common and individual-specific effects of structure-function coupling in human brain networks with graph neural networks

Chen, P.; Yang, H.; Zheng, X.; Jia, H.; Hao, J.; Xu, X.; Li, C.; He, X.; Chen, R.; Okubo, T. S.; Cui, Z.

10.1101/2023.11.22.568257 — neuroscience — Posted on 2024-03-15

2661 Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System

Dubois, J.; Field, R. M.; Jawhar, S.; Koch, E. M.; Aghajan, Z. M.; Miller, N.; Perdue, K. L.; Taylor, M.

10.1101/2024.03.12.584660 — neuroscience — Posted on 2024-03-15

2662 Gene expression shifts in Emperor penguin adaptation to the extreme Antarctic environment

Paris, J. R.; Fernandes, F. A. N.; Pirri, F.; Greco, S.; Gerdol, M.; Pallavicini, A.; Benoiste, M.; Cornec, C.; Zane, L.; Haas, B.; Le Bohec, C.; Trucchi, E.

10.1101/2023.11.29.569211 — evolutionary biology — Posted on 2024-03-15

2663 Nutrient loading from a sustainably certified aquaculture operation dwarfs annual nutrient inputs from a large multi-use watershed, Lake Yojoa, Honduras

Fadum, J.; Ross, M.; Tenorio, E.; Barby, C.; Hall, E.

10.1101/2024.03.02.583117 — ecology — Posted on 2024-03-15

2664 Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism

Arbogast, F.; Sal-Carro, R.; Boufenghour, W.; Frenger, Q.; Bouis, D.; Filippi de la Palavesa, L.; Fauny, J.-D.; Griso, O.; Puccio, H.; Fima, R.; Huby, T.; Gautier, E. L.; Molitor, A.; Carapito, R.; Bahram, S.; Romani, N.; Clausen, B. E.; Voisin, B.; Mueller, C. G.; Gros, F.; Flacher, V.

10.1101/2022.09.16.507799 — immunology — Posted on 2024-03-15

2665 Distinct neural mechanisms underlying perceptual and attentional impairments of conscious access

Noorman, S.; Stein, T.; Fahrenfort, J. J.; van Gaal, S.

10.1101/2023.10.16.562523 — neuroscience — Posted on 2024-03-15

2666 Sparse-Coding Variational Auto-Encoders

Geadah, V.; Barello, G.; Charles, A.; Pillow, J.

10.1101/399246 — neuroscience — Posted on 2024-03-15

2667 Transcriptomic and epigenomic consequences of heterozygous loss of function mutations in AKAP11, the first large-effect shared risk gene for bipolar disorder and schizophrenia

Farhangdoost, N.; Liao, C.; Liu, Y.; Alda, M.; Dion, P. A.; Rouleau, G.; Khayachi, A.; Chaumette, B.

10.1101/2024.03.14.584883 — genomics — Posted on 2024-03-15

2668 Genome streamlining: effect of mutation rate and population size on genome size reduction

Luiselli, J.; Rouzaud-Cornabas, J.; Lartillot, N.; Beslon, G.

10.1101/2024.03.14.584996 — evolutionary biology — Posted on 2024-03-15

2669 Computational Tools for the Analysis of Meiotic Prophase I Images

Crichton, J. H.; Adams, I. R.

10.1101/2023.11.15.567191 — cell biology — Posted on 2024-03-15

2670 Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling

Mühlenbeck, H.; Tsutsui, Y.; Lemmon, M.; Bender, K. W.; Zipfel, C.

10.1101/2023.08.23.554490 — biochemistry — Posted on 2024-03-15

2671 Urban birds' tolerance towards humans was largely unaffected by increased variation in human levels due to COVID-19 shutdowns

Mikula, P.; Bulla, M.; Blumstein, D.; Benedetti, Y.; Floigl, K.; Jokimaki, J.; Kaisanlahti-Jokimaki, M.-L.; Marko, G.; Morelli, F.; Moller, A. P.; Siretckaia, A.; Szakony, S.; Weston, M.; Zeid, F. A.; Tryjanowski, P.; Albrecht, T.

10.1101/2022.07.15.500232 — animal behavior and cognition — Posted on 2024-03-15

2672 Gene expression signatures of response to fluoxetine treatment: systematic review and meta-analyses

Cooper, D. G.; Cowden, J. P.; Stanley, P. A.; Karbowski, J. T.; Gaertig, V. S.; Lukan, C. J.; Vo, P. M.; Worthington, A. D.; Class, C. A.

10.1101/2024.02.19.581045 — genomics — Posted on 2024-03-15

2673 Meiosis-specific functions of kinetochore protein SPC105R required for chromosome segregation in Drosophila oocytes

Joshi, J. N.; Changela, N.; Mahal, L.; Defosse, T.; McKim, J. K.; Wang, L.-I.; Das, A.; Shapiro, J. G.; McKim, K.

10.1101/2024.03.14.585003 — genetics — Posted on 2024-03-14

2674 Assessing tooth wear progression in primates: A longitudinal study using intraoral scanning technology

Towle, I.; Krueger, K. L.; Hernando, R.; Hlusko, L. J.

10.1101/2024.03.13.584832 — evolutionary biology — Posted on 2024-03-15

2675 Causal inference with observational data and unobserved confounding variables

Byrnes, J. E. K.; Dee, L. E.

10.1101/2024.02.26.582072 — ecology — Posted on 2024-03-15

2676 FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans

Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.

10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-15

2677 The polarity protein Yurt associates with the plasma membrane via basic and hydrophobic motifs embedded in its FERM domain

Gamblin, C. L.; Alende, C.; Corriveau, F.; Jette, A.; Parent-Prevost, F.; Biehler, C.; Majeau, N.; Laurin, M.; Laprise, P.

10.1101/2023.09.28.559937 — cell biology — Posted on 2024-03-15

2678 The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophila epithelia

Goncalves, M.; Lopes, C.; Alegot, H.; Osswald, M.; Bosveld, F.; Ramos, C.; Richard, G.; Bellaiche, Y.; Mirouse, V.; Morais-de-Sa, E.

10.1101/2024.03.14.585005 — cell biology — Posted on 2024-03-14

2679 A small molecule inhibitor Mirin prevents TOP3A-dependent mtDNA breakage and segregation

Aasumets, K.; Hangas, A.; Bader, C. P. J.; Erdinc, D.; Wanrooij, S.; Wanrooij, P. H.; Goffart, S.; Pohjoismaki, J. L. O.

10.1101/2024.03.14.585071 — molecular biology — Posted on 2024-03-14

2680 Structures of transcription-translation coupling complexes at each stage of the translation cycle

Zhang, J.; Lu, G.; Zhou, W.; Yang, M.; Li, L.; Shao, H.; Zhou, X.; Chen, C.; Gao, Y.; Ebright, R. H.; Lin, J.; Wang, C.

10.1101/2024.03.13.584796 — molecular biology — Posted on 2024-03-14

2681 The specific AMPK activator A-769662 ameliorates pathological phenotypes following mitochondrial DNA depletion

Carvalho, G.; Repoles, B.; Nguyen, T. V. H.; Forslund, J. M. E.; Ranjbarian, F.; Mendes, I. C.; Falabella, M.; Doimo, M.; Wanrooij, S.; Pitceathly, R. D.; Hofer, A.; Wanrooij, P. H.

10.1101/2024.03.14.584413 — molecular biology — Posted on 2024-03-14

2682 Early life stress-induced miR-708-5p affects bipolar disorder-associated phenotypes through neuronatin downregulation

Gilardi, C.; Martins, H. C.; Lo Bianco, A.; Bicker, S.; Germain, P.-L.; Gross, F.; Sungur, A. O.; Kisko, T.; Stein, F.; Meinert, S.; Woehr, M.; Schwarting, R. K.; Dannlowski, U.; Kircher, T.; Schratt, G.

10.1101/2024.03.14.584977 — neuroscience — Posted on 2024-03-14

2683 Developmental assembly of multi-component polymer systems through interconnected gene networks in vitro

Sorrentino, D.; Ranallo, S.; Ricci, F.; Franco, E.

10.1101/2024.03.14.585044 — synthetic biology — Posted on 2024-03-14

2684 CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma

Saba, K. H.; Difilippo, V.; Styring, E.; Nilsson, J.; Magnusson, L.; van den Bos, H.; Spierings, D. C. J.; Foijer, F.; Nathrath, M.; Haglund de Flon, F.; Baumhoer, D.; Nord, K. H.

10.1101/2024.03.13.584810 — cancer biology — Posted on 2024-03-14

2685 Physical basis for the interaction between Drosophila ROS1 and the GPCR BOSS

Zhang, J.; Tsutsui, Y.; Li, H.; Li, T.; Wang, Y.; Klein, D. E.

10.1101/2024.03.13.584817 — biophysics — Posted on 2024-03-14

2686 H3-OPT: Accurate prediction of CDR-H3 loop structures of antibodies with deep learning

Tian, B.; Chen, H.; Fan, X.; Zhu, S.; Pei, Y.; Zhang, X.; Zhang, X.; Liu, L.; Qian, F.

10.1101/2023.08.19.553933 — bioinformatics — Posted on 2024-03-14

2687 Chalkophomycin Biosynthesis Revealing Unique Enzyme Architecture for a Hybrid Nonribosomal Peptide Synthetase and Polyketide Synthase

Yang, L.; Yi, L.; Gong, B.; Chen, L.; Li, M.; Zhu, X.; Duan, Y.; Huang, Y.

10.1101/2024.03.14.584926 — biochemistry — Posted on 2024-03-14

2688 Bioluminescence Imaging of Potassium Ion Using a Sensory Luciferin and an Engineered Luciferase

Zhao, S.; Xiong, Y.; Sunnapu, R.; Zhang, Y.; Tian, X.; Ai, H.

10.1101/2024.03.13.581057 — biochemistry — Posted on 2024-03-14

2689 Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

Georgaki, G.; Mpakali, A.; Trakada, M.; Papakyriakou, A.; Stratikos, E.

10.1101/2024.03.14.584938 — biochemistry — Posted on 2024-03-14

2690 idh-1 neomorphic mutation confers sensitivity to vitamin B12 via increased dependency on one-carbon metabolism in Caenorhabditis elegans

Ponomarova, O.; Starbard, A. N.; Belfi, A.; Anderson, A. V.; Sundaram, M. V.; Walhout, A. J.

10.1101/2024.03.13.584865 — biochemistry — Posted on 2024-03-14

2691 Pseudogenisation of NK3 Homeobox 2 (Nkx3.2) in Monotremes Provides Insight into Unique Gastric Anatomy and Physiology

Dann, J. B.; Qu, Z.; Shearwin-Whyatt, L.; van der Ploeg, R.; Grutzner, F.

10.1101/2024.03.13.584895 — evolutionary biology — Posted on 2024-03-14

2692 Cryptic population structure and insecticide resistance in Anopheles gambiae from the southern Democratic Republic of Congo

Dennis, T. P. W.; Pescod, P.; Barasa, S.; Cerdeira, L. T.; Lucas, E. R.; Clarkson, C. S.; Miles, A.; Asidi, A.; Manzambi, E. Z.; Metelo, E.; Zanga, J.; Salambi, S. N.; Irish, S. R.; Donnelly, M. J.; Weetman, D.; Tezzo, F. W.

10.1101/2024.03.12.584605 — evolutionary biology — Posted on 2024-03-14

2693 Czech Republic butterfly barcoding reveals that distribution of genetic lineages depends on species traits

Suchackova Bartonova, A.; Skopek, P.; Konvicka, M.; Benes, J.; Spitzer, L.; Sbaraglia, C.; Vrabec, V.; Papp Maresova, J.; Konvickova, H.; Faltynek Fric, Z.

10.1101/2024.01.17.576072 — ecology — Posted on 2024-03-14

2694 Role of non-coding RNA hsa_circ_0001495 in 16HBE cellular inflammation induced by PM2.5 and O3 combined exposure

Hongjie, W.; Yi, T.; Caixia, L.; Wenjia, J.; Ying, Y.; Xuan, M.; Xiaowu, P.

10.1101/2024.03.14.583416 — molecular biology — Posted on 2024-03-14

2695 Global 5-methylcytosine-RNA disruption reduces the vectorial competence to DENV2 of heatwave-exposed Aedes aegypti mosquitoes

Claudio-Piedras, F.; Recio, B.; Lanz, H.; Cime-Castillo, J.

10.1101/2024.03.14.585075 — molecular biology — Posted on 2024-03-14

2696 The peroxiredoxin Tsa1 extends the lifespan of budding yeast by maintaining the stability of the ribosomal RNA gene cluster.

Ohira, J.; Sasaki, M.; Kobayashi, T.

10.1101/2024.03.14.585068 — molecular biology — Posted on 2024-03-14

2697 Enhanced mucosal mitochondrial function corrects dysbiosis and OXPHOS metabolism in IBD

Kapur, N.; Alam, A.; Hassan, S. A.; Patel, P. H.; Wempe, L.; Bhogoju, S.; Goretsky, T.; Kim, J. H.; Herzog, J.; Ge, Y.; Awuah, S.; Byndloss, M.; Baumler, A. J.; Zadeh, M.; Sator, R. B.; Barrett, T. A.

10.1101/2024.03.14.584471 — molecular biology — Posted on 2024-03-14

2698 FTO-mediated m6A demethylation of ULK1 mRNA promotes autophagy and activation of hepatic stellate cells in liver fibrosis

Huang, T.; Zhang, C.; Ren, J.; Shuai, Q.; Li, X.; Li, X.; Xie, J.; Xu, J.

10.1101/2024.03.14.584975 — molecular biology — Posted on 2024-03-14

2699 Functional assessment of cell entry and receptor use for merbecoviruses

Letko, M. C.

10.1101/2024.03.13.584892 — microbiology — Posted on 2024-03-14

2700 Identification of a new family of peptidoglycan transpeptidases reveals atypical crosslinking is essential for viability in Clostridioides difficile

Bollinger, K. W.; Muh, U.; Ocius, K. L.; Apostolos, A. J.; Pires, M. M.; Helm, R. F.; Popham, D. L.; Weiss, D. S.; Ellermeier, C. D.

10.1101/2024.03.14.584917 — microbiology — Posted on 2024-03-14

2701 Versatile roles of protein flavinylation in bacterial extracyotosolic electron transfer

Huang, S.; Meheust, R.; Barquera, B.; Light, S. H.

10.1101/2024.03.13.584918 — microbiology — Posted on 2024-03-14

2702 Escherichia coli grown in cost-effective conical tubes produces more plasmid DNA

Marquez, M.; Chen, Q.; Cachaco, S.; Sui, H.; Imamichi, T.

10.1101/2024.03.13.584835 — microbiology — Posted on 2024-03-14

2703 The replication properties of a contemporary Zika virus from West Africa depends on NS1/NS4B proteins

Machmouchi, D.; Courageot, M.-P.; El-Kalamouni, C.; Kohl, A.; Despres, P.

10.1101/2024.03.14.584947 — microbiology — Posted on 2024-03-14

2704 A random mutagenesis screen enriched for missense mutations in bacterial effector proteins.

Urbanus, M. L.; Zheng, T. M.; Khusnutdinova, A. N.; Banh, D.; Mount, H. O.; Gupta, A.; Stogios, P. J.; Savchenko, A.; Isberg, R. R.; Yakunin, A. F.; Ensminger, A. W.

10.1101/2024.03.14.585084 — microbiology — Posted on 2024-03-14

2705 The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors

Wagner, S.; Malmsheimer, S.; Grin, I.; Bohn, E.; Franz-Wachtel, M.; Macek, B.; Sahr, T.; Smollich, F.; Chetrit, D.; Meir, A.; Roy, C.; Buchrieser, C.

10.1101/2024.03.14.584949 — microbiology — Posted on 2024-03-14

2706 Assessing fecal metaproteomics workflow and small protein recovery using DDA and DIA PASEF mass spectrometry

Wang, A.; Fekete, E. E.; Creskey, M.; Cheng, K.; Ning, Z.; Pfeifle, A.; Li, X.; Figeys, D.; Zhang, X.

10.1101/2024.03.13.584844 — microbiology — Posted on 2024-03-14

2707 A Toolbox for Neisseria meningitidis: Gene Editing, Complementation and Labelling

Wuckelt, M.; Laurent, A.; Mouville, C.; Meyer, J.; Jamet, A.; Lecuyer, H.; Nassif, X.; Bille, E.; Pelicic, V.; Coureuil, M.

10.1101/2024.03.14.585072 — microbiology — Posted on 2024-03-14

2708 Expanding the human gut microbiome atlas of Africa

Maghini, D. G.; Oduaran, O. H.; Wirbel, J.; Ingasia Olubayo, L. A.; Smyth, N.; Mathema, T.; Belger, C. W.; Agongo, G.; Boua, P. R.; Choma, S. S.; Gomez-Olive, F. X.; Kisiangani, I.; Mashaba, G. R.; Micklesfield, L.; Mohamed, S. F.; Nonterah, E. A.; Norris, S.; Sorgho, H.; Tollman, S.; Wafawanaka, F.; Tluway, F.; Ramsay, M.; Bhatt, A. S.; Hazelhurst, S.

10.1101/2024.03.13.584859 — microbiology — Posted on 2024-03-14

2709 Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV

Chao, C. W.; Sprouse, K. R.; Miranda, M. C.; Catanzaro, N. J.; Hubbard, M. L.; Addetia, A.; Stewart, C.; Brown, J. T.; Dosey, A.; Valdez, A.; Ravichandran, R.; Hendricks, G. G.; Ahlrichs, M.; Dobbins, C.; Hand, A.; Treichel, C.; Willoughby, I.; Walls, A. C.; McGuire, A. T.; Leaf, E. M.; Baric, R. S.; Schaefer, A.; Veesler, D.; King, N. P.

10.1101/2024.03.13.584735 — immunology — Posted on 2024-03-14

2710 Information is asymmetry: spatial relations were encoded by asymmetric mnemonic manifolds

Jiang, L.; Zhu, Y.; Liu, J.

10.1101/2024.03.13.584855 — neuroscience — Posted on 2024-03-14

2711 Exploring working memory updating processes of the human subcortex using 7T MRI

Trutti, A. C.; Sjoerds, Z.; Boag, R. J.; Walstra, S. L.; Miletic, S.; Isherwood, S. J.; Bazin, P.-L.; Hommel, B.; Habli, S.; Tse, D.; Haberg, A. K.; Forstmann, B. U.

10.1101/2024.03.14.584970 — neuroscience — Posted on 2024-03-14

2712 Synthetic dosage-compensating miRNA circuits for quantitative gene therapy

Flynn, M. J.; Mayfield, A. M.; Du, R.; Gradinaru, V.; Elowitz, M. B.

10.1101/2024.03.13.584179 — synthetic biology — Posted on 2024-03-14

2713 Inhibition of Acyl-CoA Synthetase Long Chain Isozymes Decreases Multiple Myeloma Cell Proliferation and Causes Mitochondrial Dysfunction

Murphy, C. S.; DeMambro, V. E.; Fadel, S.; Fairfield, H.; Garter, C. A.; Rodriguez, P.; Qiang, Y.-W.; Vary, C. P. H.; Reagan, M. R.

10.1101/2024.03.13.583708 — cancer biology — Posted on 2024-03-14

2714 Rare Copy Number Variant analysis in case-control studies using SNP Array Data: a scalable and automated data analysis pipeline

Artaza, H.; Lavrichenko, K.; Wolff, A. S. B.; Royrvik, E. C.; Vaudel, M.; Johansson, S.

10.1101/2024.03.13.584428 — bioinformatics — Posted on 2024-03-14

2715 Whole protein sequencing and quantification without proteolysis, terminal residue cleavage, or purification: A computational model

Sampath, G.

10.1101/2024.03.13.584825 — bioengineering — Posted on 2024-03-14

2716 Slippery sequences stall the 26S proteasome at multiple points along the translocation pathway

Ragwan, E. R.; Kisker, F. M.; Mornin, A. R.; Weiser, K. R.; Lago, A. V.; Kraut, D. A.

10.1101/2024.03.14.584990 — biochemistry — Posted on 2024-03-14

2717 Throat color polymorphism is related to differences in aggression in the Aegean wall lizard

Mandavilli, D. S.; Wang, I. J.; Brock, K. M.

10.1101/2024.03.14.585063 — animal behavior and cognition — Posted on 2024-03-14

2718 Exploring the Genomic Landscape of the GP63 family in Trypanosoma cruzi: Evolutionary Dynamics and Functional Peculiarities

Berna, L.; Chiribao, M. L.; Pita, S.; Alvarez-Valin, F.; Parodi-Talice, A.

10.1101/2024.02.17.580826 — genomics — Posted on 2024-03-14

2719 The Histone Chaperone Spn1 Preserves Subnucleosomal Structures at Promoters and Nucleosome Positioning in Open Reading Frames

Tonsager, A. J.; Zukowski, A.; Radebaugh, C. A.; Weirich, A.; Stargell, L. A.; Ramachandran, S.

10.1101/2024.03.14.585010 — genomics — Posted on 2024-03-14

2720 Evolution of Virulence in Emerging Epidemics: From Theory to Experimental Evolution and Back

Benhamou, W.; Blanquart, F.; Choisy, M.; Berngruber, T. W.; Choquet, R.; Gandon, S.

10.1101/2024.03.13.584824 — evolutionary biology — Posted on 2024-03-14

2721 Supercentenarian and remarkable age records exhibit patterns indicative of clerical errors and pension fraud

Newman, S. J.

10.1101/704080 — developmental biology — Posted on 2024-03-14

2722 YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks

Tsao, N.; Olabode, J.; Rodell, R.; Sun, H.; Brickner, J. R.; Tsai, M.-S.; Pollina, E. A.; Chen, C.-K.; Mosammaparast, N.

10.1101/2024.03.14.585107 — molecular biology — Posted on 2024-03-14

2723 Distributed encoding of hippocampal information in mossy cells

Ouchi, A.; Toyoizumi, T.; Ikegaya, Y.

10.1101/2024.03.14.584957 — neuroscience — Posted on 2024-03-14

2724 Perceptual awareness of near-threshold tones scales gradually with auditory cortex activity and pupil dilation

Doll, L.; Dykstra, A. R.; Gutschalk, A.

10.1101/2024.03.14.584980 — neuroscience — Posted on 2024-03-14

2725 Highly conserved brain vascular receptor ALPL mediates transport of engineered viral vectors across the blood-brain barrier

Moyer, T. C.; Hoffman, B. A.; Chen, W.; Shah, I.; Ren, X.-Q.; Knox, T.; Liu, J.; Wang, W.; Li, J.; Khalid, H.; Kulkarni, A. S.; Egbuchulam, M.; Clement, J.; Bloedel, A.; Child, M. A.; Kaur, R.; Rouse, E.; Graham, K.; Maura, D.; Thorpe, Z.; Sayed-Zahid, A.; Chung, C. H.-Y.; Kutchin, A.; Johnson, A.; Yao, J.; Thompson, J.; Pande, N.; Nonnenmacher, M. E.

10.1101/2024.03.12.584703 — neuroscience — Posted on 2024-03-14

2726 Astrocyte CCN1 stabilizes neural circuits in the adult brain

Sancho, L.; Boisvert, M. M.; Dawoodtabar, T.; Burgado, J.; Wang, E.; Allen, N. J.

10.1101/2024.03.14.585077 — neuroscience — Posted on 2024-03-14

2727 PEACOC - Detecting and classifying a wide range of epileptiform activity patterns in rodents

Heining, K.; Egert, U.

10.1101/2024.03.14.584961 — neuroscience — Posted on 2024-03-14

2728 Amyloid Beta Oligomers Accelerate ATP-Dependent Phase Separation of Ago2 to RNA Processing Bodies

Ray, S.; Roychowdhury, S.; Chakraborty, Y.; Banerjee, S.; Chattopadhyay, K.; Mukherjee, K.; Bhattacharyya, S. N.

10.1101/2024.03.14.584939 — neuroscience — Posted on 2024-03-14

2729 PRMT5 is required for full-length HTT expression by repressing multiple proximal intronic polyadenylation sites

ALQAZZAZ, M.; Ciamponi, F. E.; Ho, J. C.; Maron, M. I.; Yadav, M.; Sababi, A. M.; Macleod, G.; Ahmadi, M.; Bullivant, G.; Tano, V.; Langley, S. R.; Osuna, M. S.; Sachamitr, P.; Kushida, M.; Richards, L. M.; Bardile, C. F.; Pouladi, M.; Pugh, T.; Tyers, M.; Angers, S.; Dirks, P. B.; Bader, G.; Massirer, K. B.; Barsyte-Lovejoy, D.; Shechter, D.; Harding, R. J.; Arrowsmith, C.; Prinos, P.

10.1101/2024.03.14.584861 — neuroscience — Posted on 2024-03-14

2730 Association of microglia loss with hippocampal network impairments as a turning point in the amyloid pathology progression.

Pizzirusso, G.; Preka, E.; Goicolea, J.; Aguilar Ruiz, C.; Rodriguez Rodriguez, P.; Vazquez Cabrera, G.; Laterza, S.; Latorre Leal, L.; Eroli, F.; Blomgren, K.; Maioli, S.; Nilsson, P.; Fragkopoulou, A.; Fisahn, A.; Arroyo Garcia, L. E.

10.1101/2024.03.14.584993 — neuroscience — Posted on 2024-03-14

2731 Bayesian semantic surprise based on different types of regularities predicts the N400 and P600 brain signals

Hodapp, A.; Lindborg, A.; Rabovsky, M.

10.1101/2024.03.13.584794 — neuroscience — Posted on 2024-03-14

2732 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses.

Molinari, M.; Lieberman, O. J.; Sulzer, D.; Santini, E.; Borgkvist, A.

10.1101/2024.03.14.584991 — neuroscience — Posted on 2024-03-14

2733 Reactivation strength during cued recall is modulated by graph distance within cognitive maps

Kern, S.; Nagel, J.; Gerchen, M. F.; Gürsoy, C.; Meyer-Lindenberg, A.; Kirsch, P.; Dolan, R. J.; Gais, S.; Feld, G. B.

10.1101/2023.07.31.551234 — neuroscience — Posted on 2024-03-14

2734 Unraveling LIS1-Lissencephaly: Insights from Cerebral Organoids Suggest Severity-Dependent Genotype-Phenotype Correlations, Molecular Mechanisms and Therapeutic Strategies

Zillich, L.; Rossetti, A. C.; Fechtner, O.; Gasparotto, M.; Maillard, C.; Hoffrichter, A.; Zillich, E.; Jabali, A.; Marsoner, F.; Wilkens, R.; Schroeter, C. B.; Hentschel, A.; Meuth, S. G.; Ruck, T.; Koch, P.; Roos, A.; Bahi-Buisson, N.; Francis, F.; Ladewig, J.

10.1101/2022.12.19.520907 — neuroscience — Posted on 2024-03-14

2735 Convergence of inputs from the basal ganglia with layer 5 of motor cortex and cerebellum in mouse motor thalamus

Koster, K. P.; Sherman, M.

10.1101/2024.03.14.584958 — neuroscience — Posted on 2024-03-14

2736 Pavlovian cue-evoked alcohol seeking is disrupted by ventral pallidal inhibition

Richard, J. M.; Armstrong, A.; Newell, B.; Muruganandan, P.; Janak, P. H.; Saunders, B. T.

10.1101/2024.03.14.585064 — neuroscience — Posted on 2024-03-14

2737 Distractor-response binding influences visual search

Allenmark, F.; Yu, H.; Müller, H. J.; Shi, Z.; Frings, C.

10.1101/2024.03.13.584838 — neuroscience — Posted on 2024-03-14

2738 Physical activity increases neuronal activity in the circadian clock of diurnal Arvicanthis ansorgei

Caputo, R.; Schoonderwoerd, R. A.; Ramkisoensing, A.; Janse, J. A. M.; van Diepen, H. C.; Raison, S.; Pevet, P.; Derks, N. A. V.; Sage-Ciocca, D.; Deboer, T.; Challet, E.; Meijer, J.

10.1101/2022.05.31.493966 — neuroscience — Posted on 2024-03-14

2739 Dental radiography as a low-invasive field technique to estimate age in small rodents, with the mole voles (Ellobius) as an example

Nikonova, V. R.; Naumova, A. E.; Bergaliev, A. M.; Dymskaya, M. M.; Rudyk, A. I.; Volodina, E. V.; Smorkatcheva, A.

10.1101/2024.03.14.585095 — zoology — Posted on 2024-03-14

2740 Natural soil suppressiveness against soilborne phytopathogens extends to the control of insect pest

Harmsen, N.; Vesga, P.; Glauser, G.; Klötzli, F.; Heiman, C. M.; Altenried, A.; Vacheron, J.; Muller, D.; Moënne-Loccoz, Y.; Steinger, T.; Keel, C.; Garrido-Sanz, D.

10.1101/2024.03.12.584584 — plant biology — Posted on 2024-03-14

2741 Unveiling shared genetic regulators for plant architectural and biomass yield traits in sorghum

Singh, A.; Newton, L. A.; Schnable, J. C.; Thompson, A. M.

10.1101/2024.03.13.584802 — plant biology — Posted on 2024-03-14

2742 Benchmarking organ-specific responses to therapies in tissues differentiated from Cystic Fibrosis patient derived iPSCs

Daoud, A.; Xia, S.; Laselva, O.; Jiang, J. X.; Bear, C.

10.1101/2024.03.13.584768 — pharmacology and toxicology — Posted on 2024-03-14

2743 Exploiting WEE1 kinase activity as FUS::DDIT3-dependent therapeutic vulnerability in myxoid liposarcoma

Heinst, L.; Lee, K. S.; Berthold, R.; Isfort, I.; Wosnig, S.; Kuntze, A.; Hafner, S.; Altvater, B.; Roessig, C.; Aman, P.; Wardelmann, E.; Scholl, C.; Hartmann, W.; Froehling, S.; Trautmann, M.

10.1101/2024.03.13.584771 — cancer biology — Posted on 2024-03-14

2744 Biophysical metabolic modeling of complex bacterial colony morphology

Dukovski, I.; Golden, L.; Zhang, J.; Osborne, M.; Segre, D.; Korolev, K.

10.1101/2024.03.13.584915 — biophysics — Posted on 2024-03-14

2745 Application of Quantum Tensor Networks for Protein Classification

Kundu, D.; Ghosh, A.; Ekambaram, S.; Wang, J.; Dokholyan, N.; Ghosh, S.

10.1101/2024.03.11.584501 — bioinformatics — Posted on 2024-03-14

2746 Accurate cryo-EM protein particle picking by integrating the foundational AI image segmentation model and specialized U-Net

Gyawali, R.; Dhakal, A.; Wang, L.; Cheng, J.

10.1101/2023.10.02.560572 — bioinformatics — Posted on 2024-03-14

2747 BinDash 2.0: New MinHash Scheme Allows Ultra-fast and Accurate Genome Search and Comparisons

Zhao, J.; Zhao, X.; Pierre-Both, J.; Konstantinidis, K. T.

10.1101/2024.03.13.584875 — bioinformatics — Posted on 2024-03-14

2748 Identification of novel evolutionarily conserved genes and pathways in human and mouse musculoskeletal progenitors

Saravanan, S.; Devika, A. S.; Pranty, A. I.; Shaji, R.; Bhushan, R.; Adjaye, J.; Sudheer, S.

10.1101/2024.03.14.584954 — bioinformatics — Posted on 2024-03-14

2749 Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis product

Mishra, A.; Huang, S.-B.; Dubash, T.; Burr, R.; Wittner, B. S.; Cunneely, Q. E.; Putaturo, V. R.; Deshpande, A.; Antmen, E.; Gopinathan, K. A.; Otani, K.; Miyazawa, Y.; Kwak, J. E.; Guay, S. Y.; Kelly, J.; Walsh, J.; Nieman, L.; Galler, I.; Chan, P.; Lawrence, M. S.; Sullivan, R. J.; Bardia, A.; Micalizzi, D. S.; Sequist, L. V.; Lee, R. J.; Franses, J. W.; Ting, D. T.; Brunker, P. A. R.; Maheswaran, S.; Miyamoto, D. T.; Haber, D. A.; Toner, M.

10.1101/2024.03.13.583573 — bioengineering — Posted on 2024-03-14

2750 Direct Ink Writing of Graphene Oxide Reinforced 13-93B1 Bioactive Glass Scaffolds for Bone Tissue Engineering Applications

Dixit, K.; Vishwakarma, A.; Kumar, H.; Kim, K.; Sinha, N.

10.1101/2024.03.14.584172 — bioengineering — Posted on 2024-03-14

2751 Electrochemical Biosensor Using Polymer Nanocomposites for G6PD Deficiency Detection

Salas, R. R.; Paula, M. M. d. S.; Romaguera Bracelay, Y.; Brito, W.

10.1101/2024.03.13.584424 — bioengineering — Posted on 2024-03-14

2752 Unexpected transformations during pyrroloiminoquinone biosynthesis

Figueroa, J. R.; Zhu, L.; van der Donk, W.

10.1101/2024.03.12.584671 — biochemistry — Posted on 2024-03-14

2753 Neurogenomic diversity enhances collective antipredator performance in Drosophila

Sato, D. X.; Takahashi, Y.

10.1101/2024.03.14.584951 — animal behavior and cognition — Posted on 2024-03-14

2754 Evaluating machine learning algorithms to predict lameness in dairy cattle

Neupane, R.; Aryal, A.; Haeussermann, A.; Hartung, E.; Pinedo, P.; Paudyal, S.

10.1101/2024.03.13.584891 — animal behavior and cognition — Posted on 2024-03-14

2755 Reproductive restraint to avoid the costs of reproductive conflict in a cooperatively breeding mammal

Birch, G.; Nichols, H.; Mwanguhya, F.; Cant, M.; Blount, J.

10.1101/2024.03.12.584411 — animal behavior and cognition — Posted on 2024-03-14

2756 Spotlight on 10x Visium: a multi-sample protocol comparison of spatial technologies

Du, M. R. M.; Wang, C.; Law, C. W.; Amann-Zalcenstein, D.; Anttila, C. J. A.; Ling, L.; Hickey, P. F.; Sargeant, C. J.; Chen, Y.; Ioannidis, L. J.; Rajasekhar, P.; Yip, R. K. H.; Rogers, K. L.; Hansen, D. S.; Bowden, R.; Ritchie, M. E.

10.1101/2024.03.13.584910 — genomics — Posted on 2024-03-14

2757 GEGA (Gallus Enriched Gene Annotation): an online tool providing genomics and functional information across 47 tissues for a chicken gene-enriched atlas gathering Ensembl & Refseq genome annotations

DEGALEZ, F.; Bardou, P.; Lagarrigue, S.

10.1101/2024.03.13.584813 — genomics — Posted on 2024-03-14

2758 Spaceflight causes strain-dependent gene expression changes associated with lipid and extracellular matrix dysregulation in the mouse kidney in vivo

Finch, R. H.; Vitry, G.; Siew, K.; Walsh, S. B.; Beheshti, A.; Hardiman, G.; da Silveira, W. A.

10.1101/2024.03.13.584781 — genomics — Posted on 2024-03-14

2759 metaGWASmanager: A toolbox for an automated workflow from phenotypes to meta-analysis in GWAS consortia

Rodriguez-Hernandez, Z.; Gorski, M.; Tellez Plaza, M.; Schlosser, P.; Wuttke, M.

10.1101/2024.03.12.584556 — genetics — Posted on 2024-03-14

2760 A CLASP1 variant suggests a phenotypic relation with lissencephaly in humans

ALSAFH, R.; ALHASHEM, A.; ELSAYED, A.; YUEKSEL, Z.; GRAIES-TLILI, K.; THABET, F.; TABARKI, B.

10.1101/2024.03.12.584685 — genetics — Posted on 2024-03-14

2761 Experimental evolution of an RNA virus in Caenorhabditis elegans

Castiglioni, V. G.; Olmo-Uceda, M. J.; Martin, S.; Felix, M. A.; Gonzalez, R.; Elena, S. F.

10.1101/2024.03.14.584948 — evolutionary biology — Posted on 2024-03-14

2762 Circatidal control of gene expression in the deep-sea hot vent shrimp Rimicaris leurokolos

Zhang, H.; Yahagi, T.; Miyamoto, N.; Chen, C.; Jiang, Q.; Qian, P.-Y.; Sun, J.

10.1101/2024.01.12.575359 — ecology — Posted on 2024-03-14

2763 Effect of spatial overdispersion on confidence intervals for population density estimated by spatial capture-recapture

Efford, M. G.; Fletcher, D.

10.1101/2024.03.12.584742 — ecology — Posted on 2024-03-14

2764 Soil viruses reduce greenhouse gas emissions and promote microbial necromass accrual

Liang, X.; Sun, S.; Zhong, Y.; Zhang, Y.; Wang, S.; Wang, Y.; Xie, N.; Yang, L.; Radosevich, M.

10.1101/2024.03.13.584929 — ecology — Posted on 2024-03-14

2765 An unscheduled switch to endocycles induces a reversible senescent arrest thatimpairs growth of the Drosophila wing disc

Huang, Y.-T.; Hesting, L. L.; Calvi, B. R.

10.1101/2024.03.14.585098 — developmental biology — Posted on 2024-03-14

2766 Venom gland organogenesis in the common house spider

Hassan, A.; Blakeley, G.; McGregor, A. P.; Zancolli, G.

10.1101/2024.03.14.585096 — developmental biology — Posted on 2024-03-14

2767 DLG1 functions upstream of SDCCAG3 and IFT20 to control ciliary targeting of polycystin-2

Rezi, C. K.; Aslanyan, M.; Diwan, G. D.; Cheng, T.; Chamlali, M.; Junger, K.; Anvarian, Z.; lorentzen, e.; Pauly, K. B.; Bahadori, Y.; Fernandes, E. F.; Qian, F.; Tosi, S.; Christensen, S. T.; Pedersen, S. F.; Stromgaard, K.; Russell, R. B.; Miner, J. H.; Mahjoub, M. R.; Boldt, K.; Roepman, R.; Pedersen, L. B.

10.1101/2023.11.10.566524 — cell biology — Posted on 2024-03-14

2768 Regulation of Versican Expression in Macrophages is Mediated byCanonical Type I Interferon Signaling via ISGF3

Chang, M. Y.; Chan, C. K.; Brune, J. E.; Manicone, A.; Bomsztyk, K.; Frevert, C. W.; Altemeier, W. A.

10.1101/2024.03.14.585097 — cell biology — Posted on 2024-03-14

2769 Effective Gene Therapy for Metachromatic Leukodystrophy Achieved with Minimal Lentiviral Genomic Integrations

Tricoli, L.; Sase, S.; Hacker, J.; Pham, V.; Smith, S.; Chappell, M.; Breda, L.; Hurwitz, S.; Tanaka, N.; Castracani, C. C.; Guerra, A.; Hou, Z.; Schlotawa, L.; Radhakrishnan, K.; Kurre, P.; Ahrens-Nicklas, R.; Adang, L.; Vanderver, A.; Rivella, S.

10.1101/2024.03.14.584404 — molecular biology — Posted on 2024-03-14

2770 AQP1 Differentially Orchestrates Endothelial Cell Senescence

Shabanian, K.; Shabanian, T.; Karsai, G.; Lettlova, S.; Pontiggia, L.; Ruschitzka, F.; Beer, J. H.; Saeedi Saravi, S. S.

10.1101/2024.03.13.584782 — molecular biology — Posted on 2024-03-14

2771 Hsa_circ_0001304 promotes vascular smooth muscle cell autophagy and neointimal hyperplasia through the YTHDF2/mTOR axis

Mu, S.-Q.; Lin, J.-J.; Wang, Y.; Yang, L.-Y.; Wang, S.; Wang, Z.-Y.; Zhao, A.-Q.; Luo, W.-J.; Dong, Z.-Q.; Cao, Y.-G.; Jiang, Z.-A.; Wang, S.-F.; Cao, S.-H.; Meng, L.; Li, Y.; Yang, S.; Sun, S.-G.

10.1101/2024.03.13.584799 — molecular biology — Posted on 2024-03-14

2772 Experimental evolution of a reduced bacterial chemotaxis network

Kargeti, M.; Kalita, I.; Hoch, S.; Ratnikava, M.; Xu, W.; Ni, B.; Dy, R. L.; Colin, R.; Sourjik, V.

10.1101/2024.03.14.584839 — microbiology — Posted on 2024-03-14

2773 Assessing horizontal gene transfer in the rhizosphere of Brachypodium distachyon using fabricated ecosystems (EcoFABs)

Priya, S.; Rossbach, S.; Eng, T.; Andeer, P.; Lin, H.-H.; Mortimer, J.; Northen, T.; Mukhopadhyay, A.

10.1101/2024.03.14.584828 — microbiology — Posted on 2024-03-14

2774 Convergent evolution of monocyte differentiation in adult skin instructs Langerhans cell identity

Appios, A.; Davies, J.; Sirvent, S.; Henderson, S.; Trzebanski, S.; Schroth, J.; Law, M. L.; Boal Carvalho, I.; Yuan-Hao Kan, H.; Lovlekar, S.; Major, C.; Vallejo, A.; Hall, N. J.; Ardern-Jones, M.; Henson, S. M.; Emmerson, E.; Jung, S.; Polak, M. E.; Bennett, C. L.

10.1101/2023.11.13.566862 — immunology — Posted on 2024-03-14

2775 N-acetylcysteine counteracts immune dysfunction and autistic-related behaviors in the Shank3b mouse model of Autism Spectrum Disorders

Pangrazzi, L.; Cerilli, E.; Balasco, L.; Dall'O', G. M.; Chelini, G.; Pastore, A.; Weinberger, B.; Bozzi, Y.

10.1101/2024.03.13.584809 — immunology — Posted on 2024-03-14

2776 The extracellular heparan sulfatase SULF2 limits myeloid IFNbeta signaling and Th17 responses in inflammatory arthritis.

Swart, M.; Redpath, A.; Ogbechi, J.; Cardenas, R.; Topping, L.; Compeer, E. B.; Goddard, M.; Chanalaris, A.; Williams, R.; Brewer, D. S.; Smart, N.; Monaco, C.; Troeberg, L.

10.1101/2024.03.13.584823 — immunology — Posted on 2024-03-14

2777 Adoptive Transfer of CD49a+ Tissue Resident memory cells reverses pulmonary fibrosis in mice.

Collins, S. L.; Chan-Li, Y.; Shenderov, K.; Nelson, A. M.; Loube, J. M.; Mitzner, W. A.; Powell, J. D.; Horton, M. R.; Gillich, A.

10.1101/2024.03.13.584814 — immunology — Posted on 2024-03-14

2778 Pre-stimulus alpha oscillations encode stimulus-specific visual predictions

Hetenyi, D.; Haarsma, J.; Kok, P.

10.1101/2024.03.13.584593 — neuroscience — Posted on 2024-03-14

2779 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease

10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-14

2780 A genome-wide RNA interference screening reveals protectiveness of SNX5 knockdown in a Parkinson`s disease cell model

Hoellerhage, M.; Duan, L.; Chua, O. W. H.; Moebius, C.; Bothe, S.; Hopfner, F.; Wahl-Schott, C.; Bickle, M.; Hoeglinger, G. U.

10.1101/2024.03.13.584847 — neuroscience — Posted on 2024-03-14

2781 Increased perceptual reliability reduces membrane potential variability in cortical neurons

von Hünerbein, B.; Jordan, J.; Oude Lohuis, M.; Marchesi, P.; Olcese, U.; Pennartz, C. M. A.; Senn, W.; Petrovici, M. A.

10.1101/2024.03.13.584630 — neuroscience — Posted on 2024-03-14

2782 Towards an Eye-Brain-Computer Interface: Combining Gaze with the Stimulus-Preceding Negativity for Target Selections in XR

Reddy, G. S. R.; Proulx, M. J.; Hirshfield, L.; Ries, A. J.

10.1101/2024.03.13.584609 — neuroscience — Posted on 2024-03-14

2783 Forelimb movements contribute to hindlimb cutaneous reflexes during locomotion in cats

Harnie, J.; Al Arab, R.; Mari, S.; Yassine, S.; Eddaoui, O.; Jehannin, P.; Audet, J.; Lecomte, C. G.; Iorio-Morin, C.; Prilutsky, B. I.; Rybak, I. A.; Frigon, A.

10.1101/2024.03.13.584812 — neuroscience — Posted on 2024-03-14

2784 Chronically low NMNAT2 expression causes sub-lethal SARM1 activation and altered response to nicotinamide riboside in axons

Antoniou, C.; Loreto, A.; Gilley, J.; Merlini, E.; Orsomando, G.; Coleman, M. P.

10.1101/2024.03.14.584798 — neuroscience — Posted on 2024-03-14

2785 Decreasing hearing ability does not lead to improved visual speech extraction as revealed in a neural speech tracking paradigm

Haider, C. L.; Hauswald, A.; Weisz, N.

10.1101/2024.03.13.584400 — neuroscience — Posted on 2024-03-14

2786 Neurexin drives C. elegans avoidance behavior independently of its post-synaptic binding partner Neuroligin

Muirhead, C. S.; Reddy, K. C.; Guerra, S.; Rieger, M.; Hart, M. P.; Srinivasan, J.; Chalasani, S. H.

10.1101/2024.03.12.584644 — neuroscience — Posted on 2024-03-14

2787 Functional analysis of the epilepsy gene Pcdh19 using a novel GFP-reporter mouse model

Mincheva-Tasheva, S.; Scherer, M.; Robertson, L. J.; Piltz, S.; Bensalem, J.; Pederick, D. T.; Thomas, P. Q.

10.1101/2024.03.14.584898 — neuroscience — Posted on 2024-03-14

2788 The effect of gravity on hand spatio-temporal kinematic features during functional movements

Bucchieri, A.; Tessari, F.; Buccelli, S.; De Momi, E.; Laffranchi, M.; De Michieli, L.

10.1101/2023.12.05.570204 — neuroscience — Posted on 2024-03-14

2789 Reduced GABA transmission onto ventral tegmental area dopamine neurons underlies vulnerability for hyperactivity in a mouse model of Anorexia Nervosa

Ducrocq, F.; Brouwer, E.; Kooij, K. L.; Wolterink-Donselaar, I. G.; Drost, L.; Hak, J.; Veendijk, M.; Luijendijk, M. C. M.; Meye, F. J.; Adan, R. A. H.

10.1101/2024.03.14.585038 — neuroscience — Posted on 2024-03-14

2790 Enhancer-targeted CRISPR-Activation Rescues Haploinsufficient Autism Susceptibility Genes

Chen, G. T.; Nair, G.; Osorio, A. J.; Holley, S. M.; Ghassemzadeh, K.; Gonzalez, J. G.; Lu, C.; Sanjana, N. E.; Cepeda, C.; Geschwind, D.

10.1101/2024.03.13.584921 — neuroscience — Posted on 2024-03-14

2791 Defects in exosome biogenesis are associated with sensorimotor defects in zebrafish vps4a mutants

Shipman, A.; Gao, Y.; Liu, D.; Sun, S.; Zang, J.; Syed, Z.; Bhagavathi, A.; Smith, E.; Erickson, T.; Hill, M.; Neuhauss, S. C.; Sui, S.-F.; Nicolson, T.

10.1101/2024.03.13.584854 — neuroscience — Posted on 2024-03-14

2792 When visual attention is divided in the flash-lag effect

Yook, J.; Hogendoorn, H.; Fink, G. R.; Vossel, S.; Weidner, R.

10.1101/2024.03.14.585092 — neuroscience — Posted on 2024-03-14

2793 Open-Source Tools to Analyze Temporal and Spatial Properties of Local Field Potentials

Barrett, G. M.; Vajram, S. A.; Shetler, O.; Aoun, A.; Hussaini, S. A.

10.1101/2024.03.14.584529 — neuroscience — Posted on 2024-03-14

2794 Optimal motion-in-depth estimation with natural stimuli

Herrera Esposito, D.; Burge, J.

10.1101/2024.03.14.585059 — neuroscience — Posted on 2024-03-14

2795 Characterizing an electronic-robotic targeting platform for precise and fast brain stimulation with multi-locus transcranial magnetic stimulation

Matsuda, R. H.; Souza, V. H.; Marchetti, T.; De La Cruz, A. S.; Kahilakoski, O.-P.; Laine, M.; Sinisalo, H.; Kicic, D.; Lioumis, P.; Ilmoniemi, R.; Baffa, O.

10.1101/2024.03.12.584601 — neuroscience — Posted on 2024-03-14

2796 Joint contribution of adaptation and neuronal population recruitment to response level in visual area MT: a computational model

Cravo, M. I.; Bernardes, R.; Castelo-Branco, M.

10.1101/2024.03.13.584758 — neuroscience — Posted on 2024-03-14

2797 Early-life stress alters chromatin modifications in VTA to prime stress sensitivity

Geiger, L. T.; Balouek, J.-A. R.; Farrelly, L. A.; Chen, A. S.; Tang, M.; Bennett, S. N.; Nestler, E. J.; Garcia, B. A.; Maze, I.; Pena, C. J.

10.1101/2024.03.14.584631 — neuroscience — Posted on 2024-03-14

2798 Assessing Individual Sensitivity to the Thermal Grill Illusion: A Two-Dimensional Adaptive Psychophysical Approach

Sardeto Deolindo, C.; Ehmsen, J. F.; Courtin, A. S.; Mitchell, A. G.; Kraenge, C. E.; Nikolova, N.; Allen, M. G.; Fardo, F.

10.1101/2024.03.14.585017 — neuroscience — Posted on 2024-03-14

2799 Decoding the Cognitive map: Learning place cells and remapping

Pettersen, M. B.; Schoyen, V. S.; Malthe-Sorenssen, A.; Lepperod, M. E.

10.1101/2024.03.14.585049 — neuroscience — Posted on 2024-03-14

2800 The attentive reconstruction of objectsfacilitates robust object recognition

Ahn, S.; Adeli, H.; Zelinsky, G.

10.1101/2023.07.17.549340 — neuroscience — Posted on 2024-03-14

2801 Widespread variation in molecular interactions and regulatory properties among transcription factor isoforms

10.1101/2024.03.12.584681 — systems biology — Posted on 2024-03-14

2802 Viewing stomata in action: Autonomous in planta imaging of individual stomatal movement links morphology and kinetics

van den Berg, T. E.; Sanders, R. G. P.; Kaiser, E.; Schmitz, J.

10.1101/2024.03.13.584774 — plant biology — Posted on 2024-03-14

2803 The GPAT4/6/8 clade functions in Arabidopsis root suberization non-redundantly with the GPAT5/7 clade required for suberin lamellae

Gully, K.; Berhin, A.; de Bellis, D.; Herrfurth, C.; Feussner, I.; Nawrath, C.

10.1101/2024.03.13.584743 — plant biology — Posted on 2024-03-14

2804 Automated Seminal Root Angle Measurement with Corrective Annotation

Smith, A. G.; Malinowska, M.; Ruud, A. K.; Janss, L.; Krusell, L.; Jensen, J. D.; Asp, T.

10.1101/2024.03.13.584803 — plant biology — Posted on 2024-03-14

2805 The molecular basis of pine wilt disease resistance in Pinus massoniana

wang, j.; Cai, S.; Zeng, L.; Tong, J.; Hang, D.; Zhang, X.; Fang, Y.; SU, J.; Su, S.

10.1101/2024.03.13.584545 — plant biology — Posted on 2024-03-14

2806 Muscle fiber Myc is dispensable for muscle growth and forced expression severely perturbs homeostasis

Ham, D. J.; Semeraro, M.; Berger, B. M.; Lin, S.; Maino, E.; Oliveri, F.; Ruegg, M. A.

10.1101/2024.03.13.584777 — physiology — Posted on 2024-03-14

2807 Allometric multi-scaling of weight-for-height relation in children and adolescents: Revisiting the theoretical basis of body mass index of thinness and obesity assessment

Ogata, H.; Nose-Ogura, S.; Nagai, N.; Kayaba, M.; Isoyam, Y.; Kruse, J. G. S.; Selezno, I.; Kaneko, M.; Shigematsu, T.; Kiyono, K.

10.1101/2024.03.13.584792 — biophysics — Posted on 2024-03-14

2808 A possible path to persistent re-entry waves at the outlet of the left pulmonary vein

Jaeger, K. H.; Tveito, A.

10.1101/2024.03.13.584755 — biophysics — Posted on 2024-03-14

2809 Forecasting Dengue Fever in Brazil Using Multimodal Data, Including Climate Data

Danko, D. C.; Vorosmarty, C.; Cak, A.; Corsi, F.; Patel, S.; Papciak, J.; Wells, H.; Albanese, A.; Mason, C. E.; Maciel-de-Freitas, R.; Nagy-Szakal, D.; OHara, N. B.

10.1101/2024.03.12.584724 — bioinformatics — Posted on 2024-03-14

2810 An unsupervised deep learning framework encodes super-resolved image features to decode bacterial cell cycle

Griffie, J.; Zhang, C.; Denereaz, J.; Pham, T.-A. M.; Weissbart, G.; Sieben, C.; Lambert, A.; Veening, J.-W.; Manley, S.

10.1101/2024.03.13.584804 — bioinformatics — Posted on 2024-03-14

2811 Fast and accurate imputation of genotypes from noisy low-coverage sequencing data in bi-parental populations

Triay, C.; Boizet, A.; Gkanogiannis, A.; Fragoso, C.; Rami, J.-F.; Lorieux, M.

10.1101/2024.03.13.584787 — bioinformatics — Posted on 2024-03-14

2812 Cervical collagen network porosity assessed by SHG endomicroscopy distinguishes preterm and normal pregnancy - a pilot study

Liang, W.; Liu, Y.; Guan, H.; Sakulsaengprapha, V.; Luby-Phelps, K.; Mahendroo, M.; Li, X.

10.1101/2024.03.12.584664 — bioengineering — Posted on 2024-03-14

2813 Programmable marine bacteria catalyze the valorization of lignin monomers

Wei, Y.; Wang, S.-G.; Xia, P.-F.

10.1101/2024.03.12.584725 — bioengineering — Posted on 2024-03-14

2814 Initial amino acid:codon assignments and strength of codon:anticodon binding

Su, M.; Roberts, S. J.; Sutherland, J. D.

10.1101/2023.12.18.572171 — biochemistry — Posted on 2024-03-14

2815 Deciphering Immune Complexity: Single-Cell Insights into Autoimmune Myocarditis Progression

Mamdouh, F.; Abdulsahib, W. K.; Alshaya, D. S.; Fayad, E.; Eid, R. A.; Alsharif, G.; Alshehri, M. A.; Otifi, H. M.; Soltan, M. A.; Eldeen, M. A.

10.1101/2024.03.12.584698 — genomics — Posted on 2024-03-14

2816 Automated high-throughput profiling of single-cell total transcriptome with scComplete-seq

Dincaslan, F. B.; Ngang, S. W. Y.; Tan, R. Z.; Cheow, L. F.

10.1101/2024.03.12.584729 — genomics — Posted on 2024-03-14

2817 WGBS of Differentiating Adipocytes Reveals Variations in DMRs and Context-Dependent Gene Expression

Yadav, B.; Singh, D.; Mantri, S.; Rishi, V.

10.1101/2024.03.14.583264 — genomics — Posted on 2024-03-14

2818 Dimeric R25CPTH(1-34) Activates the Parathyroid Hormone-1 Receptor in vitro and Stimulates Bone Formation in Osteoporotic Female Mice

Noh, M.; Che, X.; Jin, X.; Lee, D.-K.; Kim, H.-J.; Park, D. R.; Lee, S. Y.; Lee, H.; Gardella, T. J.; Choi, J.-Y.; Lee, S.

10.1101/2024.03.13.584815 — genomics — Posted on 2024-03-14

2819 A conserved protein tyrosine phosphatase, PTPN-22, functions in diverse developmental processes in C. elegans

Binti, S.; Linder, A. G.; Edeen, P. T.; Fay, D. S.

10.1101/2024.03.12.584557 — genetics — Posted on 2024-03-14

2820 Discovery of knock-down resistance in the major malaria vector Anopheles funestus reveals the legacy of persistent DDT pollution.

Odero, J.; Dennis, T. P.; Polo, B.; Nwezeobi, J.; Bodde, M.; Nagi, S. C.; Hernandez-Koutoucheva, A.; Nambunga, I. H.; Bwanary, H.; Mkandawile, G.; Govella, N. J.; Kaindoa, E. W.; Ferguson, H. M.; Ochomo, E.; Clarkson, C. S.; Miles, A. M.; Lawniczak, M. K. N.; Weetman, D.; Baldini, F.; Okumu, F. O.

10.1101/2024.03.13.584754 — genetics — Posted on 2024-03-14

2821 Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts

Lin, X.; Gupta, D.; Vaitsiankova, A.; Bhandari, S. K.; Leung, K. S. K.; Menolfi, D.; Lee, B. J.; Russell, H. R.; Gershik, S.; Gu, W.; McKinnon, P. J.; DANTZER, F.; Rothenberg, E.; Tomkinson, A. E.; Zha, S.

10.1101/2024.03.12.584665 — genetics — Posted on 2024-03-14

2822 Savanna-forest dynamics: Encroachment speed, model inference and spatial simulations

Zelnik, Y. R.; Yatat-Djeumen, I. V.; Couteron, P.

10.1101/2024.03.12.584640 — ecology — Posted on 2024-03-14

2823 PARP14 inhibits the inflammatory response of macrophages through the NF-κB pathway

Guo, X.; Zhao, Y.

10.1101/2024.03.12.584632 — immunology — Posted on 2024-03-14

2824 Development of MHC Class I Blocking Peptides to Target Metabolic Dysfunction-Associated Steatohepatitis CD8+ T Cell Activation

Adams, V.; Sarma, S.; Hall, C. K.; Kennedy, A.

10.1101/2024.03.12.584666 — immunology — Posted on 2024-03-14

2825 PICK1 links KIBRA and AMPA receptors in coiled-coil-driven supramolecular complexes

Shao, X.; Volk, L. J.

10.1101/2024.03.12.584494 — neuroscience — Posted on 2024-03-14

2826 Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy

Feng, Y.; Diego, K. S.; Dong, Z.; Wick, Z. C.; Page-Harley, L.; Page-Harley, V.; Schnipper, J.; Lamsifer, S. I.; Pennington, Z. T.; Vetere, L. M.; Philipsberg, P. A.; Soler, I.; Jurkowski, A.; Rosado, C. J.; Khan, N. N.; Cai, D. J.; Shuman, T.

10.1101/2024.03.12.584697 — neuroscience — Posted on 2024-03-14

2827 Reliability of brain metrics derived from a Time-Domain Functional Near-Infrared Spectroscopy System

Dubois, J.; Field, R. M.; Jawhar, S.; Koch, E. M.; Aghajan, Z. M.; Miller, N.; Perdue, K. L.; Taylor, M.

10.1101/2024.03.12.584660 — neuroscience — Posted on 2024-03-14

2828 Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problem

Khodadadi, Z.; Trpevski, D.; Lindroos, R.; Hellgren Kotaleski, J.

10.1101/2024.03.12.584462 — neuroscience — Posted on 2024-03-14

2829 Adaptation to visual sparsity enhances responses to infrequent stimuli

Gou, T.; Matulis, C. A.; Clark, D. A.

10.1101/2024.03.12.584626 — neuroscience — Posted on 2024-03-14

2830 Reliance on Episodic vs. Procedural Systems in Decision-Making Depends on Individual Differences in Their Relative Neural Efficiency

Yang, Y. C.; Sibert, C.; Stocco, A.

10.1101/2023.01.10.523458 — neuroscience — Posted on 2024-03-14

2831 Sensory and perceptual decisional processes underlying the perception of reverberant auditory environments

Garcia Lazaro, H. G.; Teng, S.

10.1101/2024.03.12.584683 — neuroscience — Posted on 2024-03-14

2832 Psilocybin prevents activity-based anorexia in female rats by enhancing cognitive flexibility: contributions from 5-HT1A and 5-HT2A receptor mechanisms.

Conn, K.; Milton, L. K.; Huang, K.; Munguba, H.; Ruuska, J.; Lemus, M. B.; Greaves, E.; Homman-Ludiye, J.; Oldfield, B. J.; Foldi, C. J.

10.1101/2023.12.12.571374 — neuroscience — Posted on 2024-03-14

2833 The protein interactome of Escherichia coli carbohydrate metabolism.

Chowdhury, S.; Fong, S.; Uetz, P.

10.1101/2024.03.12.584555 — systems biology — Posted on 2024-03-14

2834 The Pivotal Involvement of the Respiratory burst oxidase G (SlRbohG) Gene in H2O2 Production Under Stress for Proper Na+ Homeostasis Regulation in Tomato

Egea, I.; Barragan-Lozano, T.; Estrada, Y.; Jaquez-Gutierrez, M.; Plasencia, F. A.; Atares, A.; Garcia-Sogo, B.; Capel, C.; Yuste-Lisbona, F. J.; Egea-Sanchez, J. M.; Borja-Flores, F.; Angosto, T.; Moreno, V.; Lozano, R.; Pineda, B.

10.1101/2024.03.12.584686 — plant biology — Posted on 2024-03-14

2835 Comparing physiological impacts of positive pressure ventilation versus self-breathing via a versatile cardiopulmonary model incorporating a novel alveoli opening mechanism

Cabeleira, M. T.; Dharmalingam, V. A.; Black, C.; Ray, S.; Ovenden, N.; Diaz, V.

10.1101/2024.03.12.584596 — physiology — Posted on 2024-03-14

2836 Sequence-defined oligophosphoesters for selective inhibition of the KRAS G12D/RAF1 interaction

Claringbold, B. R.; Vance, S.; Paul, A. R.; Garrett, M. D.; Serpell, C. D.

10.1101/2024.03.12.584553 — cancer biology — Posted on 2024-03-14

2837 Heterochromatin spreading in cancer cells through HDAC7 mediated histone H3.3 landscape reprogramming.

Hassan, O.; Pizzagalli, M.; Wu, L. J.; Karambizi, D.; Zepecki, J. P.; Fajardo, E.; Fiser, A.; Tapinos, N.

10.1101/2024.03.12.584656 — cancer biology — Posted on 2024-03-14

2838 Preclinical Results: Canine Phase I Safety Study of CM-101, a Tumor Capillary Specific Streptococcal Polysaccharide Toxin, for application in Spontaneous Canine Cancer

Stout, R. W.; Boudreaux, B.; Inegulescu, I. H.; Laine, R. A.

10.1101/2024.03.12.584502 — cancer biology — Posted on 2024-03-14

2839 Conditional c-MYC activation in catecholaminergic cells drives distinct neuroendocrine tumors: neuroblastoma vs somatostatinoma

YANG, J.; Wang, T.; Liu, L.; Fang, J.; Jin, H.; Natarajan, S.; Sheppard, H.; Lu, M.; Turner, G.; Confer, T.; Johnson, M.; Steinberg, J.; Ha, L.; Yadak, N.; Jain, R.; Picketts, D.; Ma, X.; Murphy, A.; Davidoff, A.; Glazer, E.; Easton, J.; Chen, X.; Wang, R.

10.1101/2024.03.12.584622 — cancer biology — Posted on 2024-03-14

2840 Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy

Saecker, R. M.; Mueller, A. U.; Malone, B.; Chen, J.; Budell, W. C.; Dandey, V. P.; Maruthi, K.; Mendez, J. H.; Molina, N.; Eng, E. T.; Yen, L. Y.; Potter, C. S.; Carragher, B.; Darst, S. A.

10.1101/2024.03.13.584744 — biophysics — Posted on 2024-03-14

2841 Quantifying Induced Dipole Effects in Small Molecule Permeation in a Model Phospholipid Bilayer

Montgomery, J. M.; Lemkul, J. A.

10.1101/2024.03.12.584668 — biophysics — Posted on 2024-03-14

2842 Seq2MAIT: A Novel Deep Learning Framework for Identifying Mucosal Associated Invariant T (MAIT) Cells

ElAbd, H.; Byron, R.; Woodhouse, S.; Robinett, B.; Sulc, J.; Franke, A.; Pesesky, M.; Zhou, W.; Chen-Harris, H.; Howie, B.; Taniguchi, R.; Robins, H.

10.1101/2024.03.12.584395 — bioinformatics — Posted on 2024-03-14

2843 NeuroFold: A Multimodal Approach to Generating Novel Protein Variants in silico

Amani, K.; Fish, M.; Smith, M.; Castroverde, C. D. M.

10.1101/2024.03.12.584504 — bioinformatics — Posted on 2024-03-14

2844 Fruit-In-Sight: a deep learning-based framework for secondary metabolite class prediction using fruit and leaf images

Krishnan, N. M.; Kumar, S.; Panda, B.

10.1101/2024.03.13.584746 — bioinformatics — Posted on 2024-03-14

2845 Neural Networks Estimate Muscle Force in Dynamic Conditions Better than Hill-type Muscle Models

Athanasiadou, M. E.; Daley, M. A.; Koelewijn, A. D.

10.1101/2024.03.12.584454 — bioengineering — Posted on 2024-03-14

2846 Chemical modification of hyaluronan oligosaccharides differentially modulates hyaluronan- hyaladherin interactions.

Dodd, R. J.; Blundell, C. D.; Sattelle, B. M.; Enghild, J. J.; Milner, C. M.; Day, A. J.

10.1101/2024.03.12.584658 — biochemistry — Posted on 2024-03-14

2847 DNA replication initiation drives focal mutagenesis and rearrangements in human cancers

Murat, P.; Guilbaud, G.; Sale, J. E.

10.1101/2024.03.12.584624 — genetics — Posted on 2024-03-14

2848 Aberrant homeodomain-DNA cooperative dimerization underlies distinct developmental defects in two dominant CRX retinopathy models

Zheng, Y.; Stormo, G. D.; Chen, S.

10.1101/2024.03.12.584677 — genetics — Posted on 2024-03-14

2849 Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis

Bandyadka, S.; Lebo, D. P.; Mondragon, A.; Serizier, S. B.; Kwan, J.; Peterson, J. S.; Chasse, A. Y.; Jenkins, V.; Calikyan, A.; Ortega, A.; Campbell, J. D.; Emili, A.; McCall, K.

10.1101/2024.03.12.584558 — genetics — Posted on 2024-03-14

2850 Functional characterization of QT interval associated SCN5A enhancer variants identify combined additive effects

Kapoor, A.

10.1101/2024.03.11.584440 — genetics — Posted on 2024-03-14

2851 Characterisation of Skoliomonas gen. nov., a haloalkaliphilic anaerobe related to barthelonids (Metamonada).

Eglit, Y.; Williams, S. K.; Roger, A. J.; Simpson, A. G. B.

10.1101/2024.03.12.584707 — evolutionary biology — Posted on 2024-03-14

2852 The best of two worlds: using stacked generalization for integrating expert range maps in species distribution models

Oeser, J.; Zurell, D.; Mayer, F.; Coraman, E.; Toshkova, N.; Deleva, S.; Natradze, I.; Benda, P.; Ghazaryan, A.; Irmak, S.; Hasanov, N. A.; Guliyeva, G. G.; Gritsina, M.

10.1101/2024.03.12.584552 — ecology — Posted on 2024-03-14

2853 Circular RNA circASH1L(4,5) protects microRNA-129-5p from target-directed microRNA degradation in human skin wound healing

Wang, Q.; Niu, G.; Liu, Z.; Toma, M. A.; Geara, J.; Bian, X.; Zhang, L.; Piipponen, M.; Li, D.; Sommar, P.; Xu Landen, N.

10.1101/2024.03.12.584463 — molecular biology — Posted on 2024-03-14

2854 Stiffness regulates dendritic cell and macrophage subtype development and increased stiffness induces a tumor-associated macrophage phenotype in cancer co-cultures

Guenther, C.

10.1101/2024.03.11.584525 — immunology — Posted on 2024-03-14

2855 Type I interferon alters invasive extravillous trophoblast function.

Simoni, M. K.; Negatu, S. G.; Park, J. Y.; Mani, S.; Arreguin, M.; Amses, K.; Huh, D. D.; Mainigi, M.; Jurado, K. A.

10.1101/2024.03.11.584521 — immunology — Posted on 2024-03-14

2856 Morphometric Analysis of the Thymic Epithelial Cell (TEC) Network Using Integrated and Orthogonal Digital Pathology Approaches

Lagou, M. K.; Argyris, D. G.; Vodopyanov, S.; Gunther-Cummins, L.; Hardas, A.; Poutahidis, T.; Panorias, C.; DesMarais, S.; Entenberg, C.; Carpenter, R. S.; Guzik, H.; Nishku, X.; Churaman, J.; Maryanovich, M.; DesMarais, V.; Macaluso, F. P.; Karagiannis, G. S.

10.1101/2024.03.11.584509 — immunology — Posted on 2024-03-14

2857 Investigating the Role and Regulation of GPNMB in Progranulin-deficient Macrophages

Gillett, D. A.; Neighbarger, N. K.; Cole, C.; Wallings, R.; Tansey, M. G.

10.1101/2024.03.12.584649 — immunology — Posted on 2024-03-14

2858 Pretrauma cognitive traits predict trauma-induced fear generalization and associated prefrontal functioning in a longitudinal model of posttraumatic stress disorder

Szente, L.; Aliczki, M.; Balla, G. Y.; Marothy, R. D.; Varga, Z. K.; Varga, B. A.; Borhegyi, Z.; Biro, L.; Demeter, K.; Miskolczi, C.; Balogh, Z.; Szebik, H.; Szilvasy-Szabo, A.; Kurilla, A.; Toth, M.; Mikics, E.

10.1101/2024.03.11.584500 — neuroscience — Posted on 2024-03-14

2859 Environmental complexity modulates information processing and the balance between decision-making systems

Mugan, U.; Hoffman, S. L.; Redish, A. D.

10.1101/2024.03.11.584503 — neuroscience — Posted on 2024-03-14

2860 Subject-Agnostic Transformer-Based Neural Speech Decoding from Surface and Depth Electrode Signals

Chen, J.; CHEN, X.; Wang, R.; Le, C.; Khalilian-Gourtani, A.; Jensen, E.; Dugan, P.; Doyle, W.; Devinsky, O.; Friedman, D.; Flinker, A.; Wang, Y.

10.1101/2024.03.11.584533 — neuroscience — Posted on 2024-03-14

2861 Alteration of nociceptive Schwann cells in a mouse model of peripheral neuropathy in prediabetic condition

Rastoldo, G.; Jaafar, A. K.; Paulo-Ramos, A.; Thouvenot, K.; Planesse, C.; Bringart, M.; Gonthier, M.-P.; Lambert, G.; Bourane, S.

10.1101/2024.03.12.584541 — neuroscience — Posted on 2024-03-14

2862 Frontal engagement in perceptual integration under low subjective visibility

Bae, J.; Jung, K.; James, O.; Suzuki, S.; Kim, Y. J.

10.1101/2024.03.12.584542 — neuroscience — Posted on 2024-03-14

2863 Small animal brain surgery with neither a brain atlas nor a stereotaxic frame

Ron, S.; Beeri, H.; Shinover, O.; Tur, N. M.; Brokman, J.; Engelhard, B.; Gutfreund, Y.

10.1101/2024.03.12.584491 — neuroscience — Posted on 2024-03-14

2864 Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice cultures

Sheppard, O.; Humphrey, R.; Durrant, C. S.; Coleman, M. P.

10.1101/2024.03.12.584616 — neuroscience — Posted on 2024-03-14

2865 A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimers Disease

Jin, M.; Ma, Z.; Dang, R.; Zhang, H.; Xue, H.; Pascual, J.; Finkbeiner, S.; Head, E.; Liu, Y.; Jiang, P.

10.1101/2024.03.12.584646 — neuroscience — Posted on 2024-03-14

2866 Contrast-enhanced ultrasound imaging detects anatomical and functional changes in rat cervical spine microvasculature with normal aging

Harmon, J. N.; Chandran, P.; Chandrasekaran, A.; Hyde, J. E.; Hernandez, G. J.; Reed, M. J.; Bruce, M. F.; Khaing, Z. Z.

10.1101/2024.03.12.584672 — neuroscience — Posted on 2024-03-14

2867 Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens

Martinez-Rivera, F. J.; Holt, L. M.; Minier-Toribio, A.; Estill, M.; Yeh, S.-Y.; Tofani, S.; Futamura, R.; Browne, C. J.; Mews, P.; Shen, L.; Nestler, E. J.

10.1101/2024.03.12.584637 — neuroscience — Posted on 2024-03-14

2868 Behavior can be decoded across the cortex when individual differences are considered

Nakuci, J.; Yeon, J.; Kim, J.-H.; Kim, S.-P.; Rahnev, D.

10.1101/2024.03.12.584674 — neuroscience — Posted on 2024-03-14

2869 Identification of Key Regulators in Pancreatic Ductal Adenocarcinoma using Network theoretical Approach

Ghosh, A.; Bhattacharjee, K.

10.1101/2024.03.12.584603 — systems biology — Posted on 2024-03-14

2870 Enabling Greenhouse Gas Emission Reduction while Improving Rice Yield with a Methane-Derived Microbial Biostimulant

Rajeev Kumar, S.; David, E. M.; Pavithra, G. J.; Sajith, G. K.; Lesharadevi, K.; Akshaya, S.; Bassavaraddi, C.; Navyashree, G.; Arpitha, P. S.; Sreedevi, P.; Zainuddin, K.; Saiyyeda, F.; Babu, B. R.; Prashanth, M. U.; Ravikumar, G.; Basavaraj, P.; Kumar, C. S.; Kumar, V. M. L. D.; Parthasarathi, T.; Subbian, E.

10.1101/2024.03.13.584920 — plant biology — Posted on 2024-03-14

2871 A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells

Babin-Ebell, A.; Mao, Y.; Baljkas, T.; Pilz, F.; Winkler, M.; Kuerschner, S.; Hoffarth, M.; Goerdt, S.; Reiners-Koch, P.-S.; Singhal, M.

10.1101/2024.03.11.584492 — physiology — Posted on 2024-03-14

2872 Deciphering molecular mechanisms of synergistic growth reduction in kinase inhibitor combinations

Tsirvouli, E.; Martinez del Val, A.; Thommesen, L.; Laegreid, A.; Kuiper, M.; Olsen, J. V.; Flobak, A.

10.1101/2024.03.12.584561 — cancer biology — Posted on 2024-03-14

2873 Bridging Domains in Chronic Lower Back Pain: Large Language Models and Ontology-driven Strategies for Knowledge Graph Construction

Anderson, P. E.; Davidson, J. M.; Lin, D.; Migler, T.; Ho, I.; Koenig, C.; Bittner, M.; Kaplan, S.; Paraiso, M.; Buhn, N.; Stokes, E.; Hunt, T.; Ropella, G.; Lotz, J.

10.1101/2024.03.11.584505 — bioinformatics — Posted on 2024-03-14

2874 Improving protein function prediction by learning and integrating representations of protein sequences and function labels

Boadu, F.; Cheng, J.

10.1101/2024.03.11.584495 — bioinformatics — Posted on 2024-03-14

2875 AUTO-TUNE: SELECTING THE DISTANCE THRESHOLD FOR INFERRING HIV TRANSMISSION CLUSTERS

Weaver, S.; Davila-Conn, V. M.; Ji, D.; Avila-Rios, S.; Leigh Brown, A.; Wertheim, J.; Kosakovsky Pond, S. L.

10.1101/2024.03.11.584522 — bioinformatics — Posted on 2024-03-14

2876 SCAPE-APA: a package for estimating alternative polyadenylation events from scRNA-seq data

Cheng, G.; Le, T.; Zhou, R.; Cheng, L.

10.1101/2024.03.12.584547 — bioinformatics — Posted on 2024-03-14

2877 In-Space Fabrication of Janus Base Nano-Matrix for Improved Assembly and Bioactivities

Yau, A.; Landolina, M.; Snow, M. A.; Mesci, P.; Williams, B.; Hoying, J. B.; Duflo, D.; Wu, H.; Stoudemire, J.; Hernandez, R.; Chen, Y.

10.1101/2024.03.11.584527 — bioengineering — Posted on 2024-03-14

2878 Non-invasive laser speckle imaging of extra-embryonic blood vessels in intact few-days-old avian eggs

Dong, Z.; Mahler, S.; Readhead, C.; Chen, X.; Dickson, M.; Bronner, M. E.; Yang, C.

10.1101/2024.03.11.584528 — bioengineering — Posted on 2024-03-14

2879 Whole-body simulation of realistic fruit fly locomotion with deep reinforcement learning

Vaxenburg, R.; Siwanowicz, I.; Merel, J.; Robie, A. A.; Morrow, C.; Novati, G.; Stefanidi, Z.; Card, G. M.; Reiser, M. B.; Botvinick, M. M.; Branson, K. M.; Tassa, Y.; Turaga, S. C.

10.1101/2024.03.11.584515 — animal behavior and cognition — Posted on 2024-03-14

2880 Strategic use of male alternative reproductive tactics in cooperatively breeding banded mongoose groups

Birch, G.; Nichols, H. J.; Mwanguhya, F.; Blount, J.; Cant, M.

10.1101/2024.03.11.584460 — animal behavior and cognition — Posted on 2024-03-14

2881 SLRfinder: a method to detect candidate sex-linked regions with linkage disequilibrium clustering

Yi, X.; Kemppainen, P.; Merila, J.

10.1101/2024.03.11.584532 — genomics — Posted on 2024-03-14

2882 PURIFICATION METHOD FOR ADENO-ASSOCIATED VIRAL VECTOR SEROTYPE 9 USING CERAMIC HYDROXYAPATITE CHROMATOGRAPHY AND ITS QUALIFICATION

Kurosawa, Y.; Tsunekawa, Y.; Wada, M.; Aizen, Y.; Nitahara-Kasahara, Y.; Okada, T.

10.1101/2024.03.12.584728 — molecular biology — Posted on 2024-03-14

2883 Emodin: an alveolar macrophage protector in acute pancreatitis induced lung injury

Chen, Z.; Dong, X.; Song, Y.; Lan, B.; Luo, Y.; Wen, H.; Li, H.; Chen, H.

10.1101/2024.03.12.584699 — molecular biology — Posted on 2024-03-14

2884 Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity

Brulport, A.; Gazda, M. A.; Daunesse, M.; Liorzou, E.; Raquillet, B.; Lepelletier, A.; Sopena-Rios, M.; Regnard, P.; Fellmann, L.; Faccin, L.; Garbit, S.; Cermolacce, A.; Kondova, I.; Raliou, M.; Marcellin, L.; Abo, C.; Doridot, L.; Berthelot, C.

10.1101/2024.03.13.584751 — evolutionary biology — Posted on 2024-03-14

2885 Self-inhibiting percolation and viral spreading in epithelial tissue

Xu, X.; Nielsen, B. F.; sneppen, k.

10.1101/2023.12.12.571279 — systems biology — Posted on 2024-03-14

2886 Elimination of human papillomavirus 16-induced tumors by a mucosal rAd5 therapeutic vaccination in a pre-clinical study

Braun, M. R.; Lindbloom, J. D.; Moore, A. C.; Hodgson, K. A.; Dora, E. G.; Tucker, S. N.

10.1101/2024.03.11.584519 — immunology — Posted on 2024-03-14

2887 Direct inhibitors of InhA with efficacy similar or superior to isoniazid in novel drug regimens for tuberculosis

Encinas, L.; Li, S.-Y.; Rullas-Trincado, J.; Tasneen, R.; TYAGI, S.; Soni, H.; garcia-perez, a.; Lee, J.; Gonzalez del Rio, R.; De Mercado, J.; Sousa, V.; Sosi?, I.; Gobec, S.; Mendoza-Losana, A.; Converse, P. J.; Mdluli, K.; Fotouhi, N.; BARROS-AGUIRRE, D.; Nuermberger, E. L.

10.1101/2024.03.08.584126 — pharmacology and toxicology — Posted on 2024-03-14

2888 Steppe Ancestry in western Eurasia and the spread of the Germanic Languages

McColl, H.; Kroonen, G.; Moreno-Mayar, J. V.; Valeur Seersholm, F.; Scorrano, G.; Pinotti, T.; Vimala, T.; Sindbaek, S. M.; Ethelberg, P.; Fyfe, R.; Gaillard, M.-J.; Larsen, H. M. E.; Mortensen, M. F.; Demeter, F.; Jorkov, M. L. S.; Bergerbrant, S.; Damgaard, P. d. B.; Allentoft, M. E.; Vinner, L.; Gaunitz, C.; Ramsoe, A.; Altinkaya, I.; Amund Henriksen, R.; Irving-Pease, E. K.; Sabatini, S.; Fischer, A.; Barrie, W.; Ingason, A.; Rosengren, A.; Vaughn, A.; Cao, J.; Staring, J.; Stenderup, J.; Yediay, F. E.; Ahlstrom, T.; Albris, S. L.; Atabiev, B.; Bangsgaard, P.; Belcastro, M. G.; Card, N.; C

10.1101/2024.03.13.584607 — genetics — Posted on 2024-03-14

2889 The evolutionary history of the ancient weevil family Belidae (Coleoptera: Curculionoidea) reveals the marks of Gondwana breakup and major floristic turnovers, including the rise of angiosperms

Li, X.; Marvaldi, A. E.; Oberprieler, R. G.; Clarke, D.; Farrell, B. D.; Sequeira, A.; Ferrer, M. S.; O'Brien, C.; Salzman, S.; Shin, S.; Tang, W.; McKenna, D. D.

10.1101/2024.03.12.584611 — evolutionary biology — Posted on 2024-03-14

2890 Nanoparticles alter the nature and strength of intraploidy and interploidy interactions in plants

Esser, E. A.; Tan, J.; Wei, N.

10.1101/2024.03.11.584520 — ecology — Posted on 2024-03-14

2891 Non-linear development of EEG coherence in adolescents and young adults shown by the analysis of neurophysiological trajectories and their covariance

Chorlian, D. B.; Kamarajan, C.; Meyers, J. L.; Pandey, A. K.; Zhang, J.; Kinreich, S.; Porjesz, B.

10.1101/2024.03.13.584867 — developmental biology — Posted on 2024-03-14

2892 Engineered Migrasomes: A Robust, Thermally Stable Vaccination Platform

Wang, D.; Wang, H.; Wan, W.; Zhu, Z.; Sho, T.; Zheng, Y.; Zhang, X.; Dou, L.; Ding, Q.; Yu, L.; Liu, Z.

10.1101/2024.03.13.584850 — cell biology — Posted on 2024-03-14

2893 The β2-adrenergic receptor (ADRB2) entrains circadian gene oscillation and diurnal responses to virus infection in CD8+ T cells

Sharma, D.; Kohlbach, K. A.; Maples, R.; Farrar, J. D.

10.1101/2024.03.12.584692 — immunology — Posted on 2024-03-14

2894 A biological model of nonlinear dimensionality reduction

Yoshida, K.; Toyoizumi, T.

10.1101/2024.03.13.584757 — neuroscience — Posted on 2024-03-14

2895 Primate thalamic nuclei select abstract rules and shape prefrontal dynamics

Phillips, J. M.; Afrasiabi, M.; Kambi, N. A.; Redinbaugh, M. J.; Steely, S.; Johnson, E. R.; Cheng, X.; Fayyad, M.; Mohanta, S.; Caris, A.; Mikell, C. B.; Mofakham, S.; Saalmann, Y. B.

10.1101/2024.03.13.584871 — neuroscience — Posted on 2024-03-14

2896 Protection against APOE4-associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice

McGill, C. J.; Christensen, A.; Qian, W.; Thorwald, M. A.; Lugo, J. G.; Namvari, S.; White, O. S.; Finch, C.; Benayoun, B. A.; Pike, C. J.

10.1101/2024.03.12.584678 — systems biology — Posted on 2024-03-14

2897 Molecular signatures and associated regulators of the pea leaf response to sulfur deficiency and water deficit as revealed by multi-omics analyses

Bonnot, T.; Henriet, C.; Aime, D.; Kreplak, J.; Terezol, M.; Balliau, T.; Ourry, A.; Zivy, M.; Vernoud, V.; Gallardo, K.

10.1101/2024.03.13.582463 — plant biology — Posted on 2024-03-14

2898 Assessing Long-Term Stored Tissues for Multi-Omics Data Quality and Proteogenomics Suitability

Song, K. J.; Kim, M.; Heo, Y. J.; Cho, K.-C.; Oh, J.-W.; Kim, D. H.; Hwa, C.; Do, Y.; Choi, S.; Hwang, H. S.; Kim, K.; Kim, K.; Na, S.; Paek, E.; An, J.-Y.; Jang, S. J.; Kim, M.-S.; Kim, K. P.

10.1101/2024.03.13.583805 — cancer biology — Posted on 2024-03-14

2899 Proteomic Analysis Reveals Trilaciclib-Induced Senescence

Hermosilla-Trespaderne, M.; Hu-Yang, M. X.; Dannoura, A.; Frey, A. M.; George, A. L.; Trost, M.; Marin-Rubio, J. L.

10.1101/2024.03.12.584620 — cancer biology — Posted on 2024-03-14

2900 CDK4 and CDK6 upregulation promotes DNA replication stress, genomic instability and resistance to EGFR targeted therapy in lung cancer

Gini, B.; Gui, P.; Wu, W.; Kerr, D. L.; Tan, L.; Barbosa, D.; Olivas, V.; Gomez, C.; Elmes, S.; Steri, V.; Chakrabarti, T.; Bivona, T. G.; Blakely, C. M.

10.1101/2024.03.12.584638 — cancer biology — Posted on 2024-03-14

2901 Comparative Evaluation of Bioinformatic Pipelines for Full-Length Viral Genome Assembly

Zsichla, L.; Zeeb, M.; Fazekas, D.; Ay, E.; Muller, D.; Metzner, K.; Kouyos, R.; Muller, V.

10.1101/2024.03.13.584779 — bioinformatics — Posted on 2024-03-14

2902 CircRNA-Pro: A Novel Toolkit for High-Precision Detection of Differentially Expressed Circular RNAs and Translatable Circular RNAs

Song, W.; Yu, L.; Ye, T.; Zhang, H.; Wang, Y.; Yang, Y.; Shen, D.; Piao, W.; Jin, H.

10.1101/2024.03.13.584785 — bioinformatics — Posted on 2024-03-14

2903 Harnessing Genome Representation Learning for Decoding Phage-Host Interactions

Badam, S.; Rao, S.

10.1101/2024.03.12.584599 — bioinformatics — Posted on 2024-03-14

2904 Differential expression and co-expression reveal cell types relevant to rare disease phenotypes

Alias-Segura, S.; Pazos, F.; Chagoyen, M.

10.1101/2024.03.12.584594 — bioinformatics — Posted on 2024-03-14

2905 Computational screening of the effects of mutations on protein-protein off-rates and dissociation mechanisms by {tau}RAMD

D'Arrigo, G.; Kokh, D. B.; Nunes-Alves, A.; Wade, R. C.

10.1101/2024.03.12.584688 — bioinformatics — Posted on 2024-03-14

2906 tstrait: a quantitative trait simulator for ancestralrecombination graphs

Tagami, D.; Bisschop, G.; Kelleher, J.

10.1101/2024.03.13.584790 — bioinformatics — Posted on 2024-03-14

2907 Tribus: Semi-automated discovery of cell identities and phenotypes from multiplexed imaging and proteomicdata

Kang, Z.; Szabo, A.; Farago, T.; Perez-Villatoro, F.; Launonen, I.-M.; Anttila, E.; Elias, K.; Casado, J.; Sorger, P. K.; Farkkila, A.

10.1101/2024.03.13.584767 — bioinformatics — Posted on 2024-03-14

2908 GDFold2: a fast and parallelizable protein folding environment with freely defined objective functions

Mi, T.; Gong, H.

10.1101/2024.03.13.584741 — bioinformatics — Posted on 2024-03-14

2909 The repetitive genome of the Ixodes ricinus tick reveals transposable elements have driven genome evolution in ticks

Ronai, I.; de Paula Baptista, R.; Paulat, N. S.; Frederick, J.; Azagi, T.; Bakker, J.; Dillon, K. C.; Sprong, H.; Ray, D. A.; Glenn, T.

10.1101/2024.03.13.584159 — genomics — Posted on 2024-03-14

2910 The dynamic genomes of Hydra and the anciently active repeat complement of animal chromosomes

Kon-Nanjo, K.; Kon, T.; Koubkova Yu, T. C.-T.; Rodriguez-Terrones, D.; Falcon, F.; Martinez, D. E.; Steele, R. E.; Tanaka, E. M.; Holstein, T. W.; Simakov, O.

10.1101/2024.03.13.584568 — genomics — Posted on 2024-03-14

2911 The GC-content at the 5'ends of human protein-coding genes is undergoing mutational decay

Qiu, Y.; Kang, Y. M.; Korfmann, C.; Pouyet, F.; Eckford, A.; Palazzo, A. F.

10.1101/2024.03.12.584636 — genomics — Posted on 2024-03-14

2912 Diverse origins of near-identical antifreeze proteins in unrelated fish lineages provide insights into evolutionary mechanisms of new gene birth and protein sequence convergence

Rives, N.; Lamba, V.; Cheng, C.- H. C.; Zhuang, X.

10.1101/2024.03.12.584730 — evolutionary biology — Posted on 2024-03-14

2913 Ant queens cannibalise infected brood to contain disease spread and recycle nutrients

Bizzell, F.; Pull, C. D.

10.1101/2024.03.13.584778 — evolutionary biology — Posted on 2024-03-14

2914 The Mycobacterium tuberculosis complex pangenome is small and driven by sub-lineage-specific regions of difference

Behruznia, M.; Marin, M.; Farhat, M. R.; Thomas, J. C.; Domingo-Sananes, M. R.; Meehan, C. J.

10.1101/2024.03.12.584580 — evolutionary biology — Posted on 2024-03-14

2915 De novo evolution of transmissible tumors in Hydra

Tissot, S.; Meliani, J.; Boutry, J.; Brazier, L.; Tökkölyi, J.; Roche, B.; Ujvari, B.; Nedelcu, A. M.; Thomas, F.; Dujon, A. M.

10.1101/2024.03.13.584762 — evolutionary biology — Posted on 2024-03-14

2916 Temporal and spatial variability in availability bias has consequences for marine bird abundance estimates during the non-breeding season

Dunn, R. E.; Duckworth, J.; O'Brien, S.; Furness, R. W.; Buckingham, L.; Daunt, F.; Bogdanova, M. I.; Green, J. A.

10.1101/2024.03.13.584773 — ecology — Posted on 2024-03-14

2917 What makes clocks tick? Characterizing developmental dynamics of adult epigenetic clock sites

Mulder, R. H.; Neumann, A.; Felix, J. F.; Suderman, M.; Cecil, C. A. M.

10.1101/2024.03.12.584597 — developmental biology — Posted on 2024-03-14

2918 A Foxf1-Wnt-Nr2f1 cascade promotes atrial cardiomyocyte differentiation in zebrafish

Coppola, U.; Kenney, J.; Waxman, J. S.

10.1101/2024.03.13.584759 — developmental biology — Posted on 2024-03-14

2919 Eed controls craniofacial osteoblast differentiation and mesenchymal proliferation from the neural crest

Casey-Clyde, T.; Liu, S. J.; Serrano, J. A. C.; Teng, C.; Jang, Y.-G.; Vasudevan, H. N.; Bush, J. O.; Raleigh, D. R.

10.1101/2024.03.13.584903 — developmental biology — Posted on 2024-03-14

2920 Multivalent 28S rRNA Is the Organizer of the Nucleolus's Multi-layered Architecture

Wei, J.; Zhang, Y.; Ye, B.; Fan, X.; Hu, Y.; Xiang, S.; Ma, W.

10.1101/2024.03.13.584914 — cell biology — Posted on 2024-03-14

2921 Oligonucleotide insecticides (contact unmodified antisense DNA biotechnology) and RNA biocontrols (double-stranded RNA technology): newly born fraternal twins in plant protection

Oberemok, V.; Gal'chinsky, N.

10.1101/2024.03.13.584797 — molecular biology — Posted on 2024-03-14

2922 Intraspecific venom variation in the medically important puff adder (Bitis arietans): comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

Dawson, C. A.; Bartlett, K. E.; Wilkinson, M. C.; Ainsworth, S.; Albulescu, L.-O.; Kazandjian, T.; Hall, S. R.; Westhorpe, A.; Clare, R. H.; Wagstaff, S.; Modahl, C. M.; Harrison, R. A.; Casewell, N. R.

10.1101/2024.03.13.584772 — molecular biology — Posted on 2024-03-14

2923 A longevity-specific bank of induced pluripotent stem cells from centenarians and their offspring

Dowrey, T. W.; Cranston, S. F.; Skvir, N.; Lok, Y.; Gould, B.; Petrowitz, B.; Villar, D.; Shan, J.; James, M.; Dodge, M.; Belkina, A. C.; Giadone, R. M.; Sebastiani, P.; Perls, T. T.; Andersen, S. L.; Murphy, G. J.

10.1101/2024.03.12.584663 — molecular biology — Posted on 2024-03-14

2924 Differentiation marker-negative CD4+ T cells persist after yellow fever virus vaccination and contribute to durable memory

Pan, Y.-G.; Bartolo, L.; Xu, R.; Patel, B.; Zarnitsyna, V. I.; Su, L. F.

10.1101/2024.03.11.584523 — immunology — Posted on 2024-03-14

2925 Mutability and hypermutation antagonize immunoglobulin codon optimality

McGrath, J. J.; Park, J.; Troxell, C. A.; Chervin, J. C.; Li, L.; Kent, J. R.; Changrob, S.; Fu, Y.; Huang, M.; Zheng, N.-Y.; Wilbanks, G. D.; Nelson, S. A.; Sun, J.; Inghirami, G.; Madariaga, M. L. L.; Georgiou, G.; Wilson, P. C.

10.1101/2024.03.13.584690 — immunology — Posted on 2024-03-14

2926 Algebraic structures emerge from the self-supervised learning of natural sounds.

Orhan, P.; Boubenec, Y.; King, J.-R.

10.1101/2024.03.13.584776 — neuroscience — Posted on 2024-03-14

2927 Flies tune the sensitivity of their multifunctional gyroscope.

Verbe, A.; Lea, K. M.; Fox, J. L.; Dickerson, B. H.

10.1101/2024.03.13.583703 — neuroscience — Posted on 2024-03-14

2928 Transcriptional and neurochemical signatures of cerebral blood flow alterations in schizophrenia and the clinical high-risk state for psychosis

Knight, S. R.; Abbasova, L.; Zeighami, Y.; Hansen, J. Y.; Martins, D.; Zelaya, F.; Dipasquale, O.; Liu, T.; Shin, D.; Bossong, M. G.; Azis, M.; Antoniades, M.; Howes, O. D.; Bonoldi, I.; Egerton, A.; Allen, P.; O'Daly, O.; McGuire, P.; Modinos, G.

10.1101/2024.03.13.583894 — neuroscience — Posted on 2024-03-14

2929 Dissociable Roles of the mPFC-to-VTA Pathway in the Control of Impulsive Action and Risk-Related Decision-Making in Roman High- and Low-Avoidance Rats.

Uruena-Mendez, G.; Arrondeau, C.; Marchessaux, F.; Goutaudier, R.; Ginovart, N.

10.1101/2024.03.13.584562 — neuroscience — Posted on 2024-03-14

2930 Bayesian inference of state feedback control parameters for fo perturbation responses in cerebellar ataxia

Gaines, J. L.; Kim, K. S.; Parrell, B.; Ramanarayanan, V.; Pongos, A. L.; Nagarajan, S. S.; Houde, J. F.

10.1101/2024.03.12.584554 — neuroscience — Posted on 2024-03-14

2931 Computational analysis of SOD1-G93A mouse muscle biomarkers for comprehensive assessment of ALS progression

Gomez-Galvez, P. J.; Navarro, V.; Castro, A. M.; Paradas, C.; Escudero, L. M.

10.1101/2024.03.11.584407 — neuroscience — Posted on 2024-03-14

2932 Stem rot affects the structure of rhizosphere microbiome in Berseem Clover (Trifolium alexandrinum)

Mukhtar, S.; Ahmad, Z.; Khan, N.; John, M.; Aiysha, D.

10.1101/2024.03.13.584667 — plant biology — Posted on 2024-03-14

2933 Estimating evolutionary and demographic parameters via ARG-derived IBD

Huang, Z.; Kelleher, J.; Chan, Y.-b.; Balding, D.

10.1101/2024.03.07.583855 — genetics — Posted on 2024-03-13

2934 The pivotal role of Drgx in survival, wiring and identity of T4/T5 neurons

Gizler, L.; Schneider, K.; Steigleder, S.; Benmaamar, S.; Schneuwly, S.; Rass, M.

10.1101/2024.03.12.584653 — developmental biology — Posted on 2024-03-14

2935 Spatial Dynamics of the Developing Human Heart

Lazar, E.; Mauron, R.; Andrusivova, Z.; Foyer, J.; Larsson, L.; Shakari, N.; Salas, S. M.; Sariyar, S.; Hansen, J. N.; Vicari, M.; Czarnewski, P.; Braun, E.; Li, X.; Bergmann, O.; Sylven, C.; Lundberg, E.; Linnarsson, S.; Nilsson, M.; Sundstrom, E.; Adameyko, I.; Lundeberg, J.

10.1101/2024.03.12.584577 — developmental biology — Posted on 2024-03-14

2936 Endogenous Nodal switches Wnt interpretation from posteriorization to germ layer differentiation in geometrically constrained human pluripotent cells

Ortiz-Salazar, M. A.; Camacho-Aguilar, E.; Warmflash, A.

10.1101/2024.03.13.584912 — developmental biology — Posted on 2024-03-14

2937 Visualizing histone H4K20me1 in knock-in mice expressing the mCherry-tagged modification-specific intracellular antibody

Sato, Y.; Takenoshita, M.; Ueoka, M.; Ueda, J.; Yamagata, K.; Kimura, H.

10.1101/2024.03.13.584715 — cell biology — Posted on 2024-03-14

2938 Two brain systems for the perception of geometric shapes

Sable-Meyer, M.; Benjamin, L.; Watkins, C. P.; He, C.; Al Roumi, F.; Dehaene, S.

10.1101/2024.03.13.584141 — neuroscience — Posted on 2024-03-14

2939 QClus: A droplet-filtering algorithm for enhanced snRNA-seq data quality in challenging samples

Schmauch, E.; Ojanen, J.; Galani, K.; Jalkanen, J.; Harju, K.; Hollmen, M.; Kokki, H.; Gunn, J.; Halonen, J.; Hartikainen, J.; Kiviniemi, T.; Tavi, P.; Kaikkonen, M. U.; Kellis, M.; Linna-Kuosmanen, S.

10.1101/2022.10.21.513315 — genomics — Posted on 2024-03-13

2940 Decoding the complexity of delayed wound healing following Enterococcus faecalis infection

Celik, C.; Lee, S. Y. T.; Reinhart Tanoto, F.; Veleba, M.; Kline, K. A.; Thibault, G.

10.1101/2023.11.16.566967 — microbiology — Posted on 2024-03-13

2941 Characterization of natural product inhibitors of quorum sensing in Pseudomonas aeruginosa reveals competitive inhibition of RhlR by ortho-vanillin

Woods, K. E.; Akhter, S.; Rodriguez, B. L.; Townsend, K. A.; Smith, N. C.; Wambua, A. N.; Craddock, V.; Santa, E. E.; Manson, D. E.; Abisado-Duque, R. G.; Oakley, B. R.; Hancock, L. E.; Miao, Y.; Blackwell, H. E.; Chandler, J. R.

10.1101/2024.02.24.581676 — microbiology — Posted on 2024-03-13

2942 Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction

Onos, K. D.; Lin, P. B.; Pandy, R. S.; Persohn, S. A.; Burton, C. P.; Miner, E. W.; Eldridge, K.; Kanyinda, J. N.; Foley, K. E.; Carter, G. W.; Howell, G. R.; Territo, P. R.

10.1101/2023.12.13.571584 — neuroscience — Posted on 2024-03-13

2943 Monkeys have rhythm

Rajendran, V. G.; Marquez, J. P.; Prado, L.; Merchant, H.

10.1101/2024.03.11.584468 — neuroscience — Posted on 2024-03-13

2944 Development of a series of genetically engineered NTRK fusion-driven pediatric-type high-grade glioma mouse models

10.1101/2024.03.13.584849 — cancer biology — Posted on 2024-03-13

2945 The Cyclin-Like Protein Spy1 Mediates Tumourigenic Potential of Triple Negative Breast Cancer

Fifield, B.-A.; Pecoraro, C.; Basilious, A.; Gramisteanu, C.; Mailloux, E.; Ferraiuolo, R.-M.; Porter, L. A.

10.1101/2024.03.11.584461 — cancer biology — Posted on 2024-03-13

2946 Metaplastic tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer

Salas-Escabillas, D. J.; Hoffman, M. T.; Moore, J. S.; Brender, S. M.; Wen, H.-J.; Benitz, S.; Davis, E. T.; Long, D.; Wombwell, A. M.; Steele, N. G.; Sears, R. C.; Matsumoto, I.; DelGiorno, K. E.; Crawford, H. C.

10.1101/2024.02.12.579982 — cancer biology — Posted on 2024-03-13

2947 PIP2-Dependent Thermoring Basis for Cold-Sensing of the TRPM8 Biothermometer

Wang, G.

10.1101/2022.01.02.474742 — biophysics — Posted on 2024-03-13

2948 Membrane Lipid Domains Modulate HCN Channels in Nociceptor DRG Neurons

Handlin, L. J.; Macchi, N. L.; Dumaire, N.; Salih, L.; McCommis, K. S.; Moutal, A.; Dai, G.

10.1101/2023.09.02.556056 — biophysics — Posted on 2024-03-13

2949 Diffusive lensing as a mechanism of intracellular transport and compartmentalization

Raja Venkatesh, A.; Le, K. H.; Weld, D. M.; Brandman, O.

10.1101/2022.08.30.505927 — biophysics — Posted on 2024-03-13

2950 Elucidating the influence of RNA modifications and Magnesium ions on tRNAPhe conformational dynamics in S. cerevisiae: Insights from Replica Exchange Molecular Dynamics simulations

Nowzari, Z. R.; D'Esposito, R. J.; Chen, A. A.; Vangaveti, S.

10.1101/2024.03.11.584441 — bioinformatics — Posted on 2024-03-13

2951 HPClas: A data-driven approach for identifying halophilic proteins based on catBoost

Shantong, H.; Zhikang, W.; Xiaoyu, W.; Yongfei, C.; Yun, T.; Zhuoqian, L.; Menghan, J.; Shihui, W.; wenya, W.; Guimin, Z.; Jiangning, S.

10.1101/2023.11.30.569348 — bioinformatics — Posted on 2024-03-13

2952 Simpler protein domain identification using spectral clustering

Cazals, F.; Herrmann, J.; Sarti, E.

10.1101/2024.02.10.579762 — bioinformatics — Posted on 2024-03-13

2953 Dynamic culture of cerebral organoids using a pillar/perfusion plate for the assessment of developmental neurotoxicity

Acharya, P.; Shrestha, S.; Joshi, P.; Choi, N. Y.; Lekkala, V. K. R.; Kang, S.-Y.; Ni, G.; Lee, M.-Y.

10.1101/2024.03.11.584506 — bioengineering — Posted on 2024-03-13

2954 Development and application of GlycanDIA workflow for glycomic analysis

Xie, Y.; Liu, X.; Zhao, C.; Chen, S.; Wang, S.; Lin, Z.; Robison, F. M.; George, B. M.; Flynn, R. A.; Lebrilla, C. B.; Garcia, B. A.

10.1101/2024.03.12.584702 — biochemistry — Posted on 2024-03-13

2955 The chromokinesin Kid forms a homodimer and moves processively along microtubules

Niwa, S.; Furusaki, N.; Kita, T.; Chiba, K.

10.1101/2024.03.13.584902 — biochemistry — Posted on 2024-03-13

2956 Sulfite oxidase deficiency causes persulfidation loss and H2S release

Fu, C.-Y.; Kohl, J. B.; Liebsch, F.; D`Andrea, D.; Mai, M.; Mellis, A. T.; Kouroussis, E.; Ditroi, T.; Santamaria-Araujo, J. A.; Yeo, S. Y.; Endepols, H.; Krizkov, M.; Kozich, V.; Barayeu, U.; Akaike, T.; Hennermann, J. B.; Nagy, P.; Filipovic, M.; Schwarz, G.

10.1101/2024.03.13.584820 — biochemistry — Posted on 2024-03-13

2957 A multi-modal image fusion workflow incorporating MALDI imaging mass spectrometry and microscopy for the study of small pharmaceutical compounds

Liang, Z.; Guo, Y.; Sharma, A.; McCurdy, C. R.; Prentice, B. M.

10.1101/2024.03.12.584673 — biochemistry — Posted on 2024-03-13

2958 Differences in Protein Capture by SP3 and SP4 Demonstrate Mechanistic Insights of Proteomics Clean-up Techniques

Conforti, J. M.; Ziegler, A. M.; Worth, C. S.; Nambiar, A. M.; Bailey, J. T.; Taube, J. H.; Gallagher, E. S.

10.1101/2024.03.13.584881 — biochemistry — Posted on 2024-03-13

2959 Anti-fungal recombinant psoriasin effectively inhibits Candida albicans growth on denture base

Lifshits, L. A.; Brohnshtein, E.; Attias, M.; Breuer, Y.; Cohen, A.; Gabay, M.; Sova, M.; Weinberg, E.; Zenziper, E.; Bar, D. Z.; Sterer, N.; Gal, M.

10.1101/2024.03.12.584579 — biochemistry — Posted on 2024-03-13

2960 Structural basis for Retriever-SNX17 assembly and endosomal sorting

Singla, A.; Boesch, D. J.; Fung, H. Y. J.; Ngoka, C.; Enriquez, A. S.; Song, R.; Kramer, D. A.; Han, Y.; Juneja, P.; Billadeau, D. D.; Bai, X.; Chen, Z.; Turer, E. E.; Burstein, E.; Chen, B.

10.1101/2024.03.12.584676 — biochemistry — Posted on 2024-03-13

2961 SARS-CoV-2 methyltransferase nsp10-16 in complex with natural and drug-like purine analogs for guiding structure-based drug discovery

Kremling, V.; Falke, S.; Fernandez-Garcia, Y.; Ehrt, C.; Kiene, A.; Klopprogge, B.; Scheer, T. E. S.; Barthels, F.; Middendorf, P.; Kuehn, S.; Guenther, S.; Rarey, M.; Chapman, H. N.; Oberthuer, D.; Sprenger, J.

10.1101/2024.03.13.583470 — biochemistry — Posted on 2024-03-13

2962 Thoughtful faces: inferring internal states across species using facial features

Tlaie, A.; Abd El Hay, M. Y.; Mert, B.; Taylor, R.; Ferracci, P. A.; Shapcott, K. A.; Glukhova, M.; Pillow, J. W.; Havenith, M. N.; Scholvinck, M.

10.1101/2024.01.24.577055 — animal behavior and cognition — Posted on 2024-03-13

2963 Genotype prediction of 336,463 samples from public expression data

Razi, A.; Lo, C. C.; Wang, S.; Leek, J. T.; Hansen, K. D.

10.1101/2023.10.21.562237 — genetics — Posted on 2024-03-13

2964 MASCOT-Skyline integrates population and migration dynamics to enhance phylogeographic reconstructions

Müller, N. F.; Bouckaert, R. R.; Wu, C.-H.; Bedford, T. F.

10.1101/2024.03.06.583734 — evolutionary biology — Posted on 2024-03-13

2965 Development in context: interferon response networks regulate human fetal thymic epithelial cell differentiation

Mohammed, A.; Solomon, B.; Slepicka, P. F.; Hubka, K. M.; Nguyen, H. D.; Wang, W.; Arreola, M.; Chavez, M. G.; Yeh, C. Y.; Kim, D. K.; Winn, V. D.; Gifford, C. A.; Kedlian, V.; Park, J.-E.; Hollander, G. A.; Sebastiano, V.; Khatri, P.; Teichmann, S. A.; Gentles, A.; Weinacht, K. G.

10.1101/2022.10.02.510339 — developmental biology — Posted on 2024-03-13

2966 Cell surface morphology mimicking nano-bio platform for immune cell stimulation

Varghese, B.; Gonzalez-Navarro, J. A.; Guerra, V. L. P.; Faizulina, M.; Artemieva, D.; Chum, T.; Ramakrishna, T. R. B.; Cebecauer, M.; Kovaricek, P.

10.1101/2024.01.23.576453 — cell biology — Posted on 2024-03-13

2967 Changes in the senescence profile and immune checkpoints in HIV-infected individuals after COVID-19

Crespo-Bermejo, C.; Brochado-Kith, O.; Grande-Garcia, S.; Lara-Aguilar, V.; Llamas-Adan, M.; Arca-Lafuente, S.; Martin-Carbonero, L.; de los Santos, I.; Jimenez Sousa, M. A.; Resino, S.; Berenguer, J.; Madrid, R.; Fernandez-Rodriguez, A.; Briz, V.

10.1101/2024.03.12.584682 — microbiology — Posted on 2024-03-13

2968 Detection of oat crown rust disease in Taiwan (2019-2021)

Ho, C.-Y.; Henningsen, E.; Chen, S.-T.; Ariyawansa, H. A.; Nazareno, E. C.; Sperschneider, J.; Dodds, P.; Riddle, J. M.; Kianian, S. F.; Figueroa, M.; Huang, Y.-F.

10.1101/2024.03.12.584714 — microbiology — Posted on 2024-03-13

2969 Spatial integration of sensory input and motor output in Pseudomonas aeruginosa chemotaxis through colocalized distribution

Wu, Z.; Tian, M.; Fu, S.; Chen, M.; Zhang, R.; Yuan, J.

10.1101/2024.03.13.584826 — microbiology — Posted on 2024-03-13

2970 De novo Genome Sequencing and Annotation of a Thermophilic Cyanobacterium using the Oxford Nanopore Technologies Sequencing Platform

Woortman, D. V.; Kandawa-Schulz, M.; Mehlmer, N.; Brueck, T.

10.1101/2024.03.13.584795 — microbiology — Posted on 2024-03-13

2971 The Role of Ebola Virus VP24 Nuclear Trafficking Signals in Infectious Particle Production

Vogel, O. A.; Nafziger, E.; Sharma, A.; Pasolli, H. A.; Davey, R. A.; Basler, C. F.

10.1101/2024.03.13.584761 — microbiology — Posted on 2024-03-13

2972 The Structure of the Lujo Virus Spike Complex

Eilon-Ashkenazy, M.; Cohen-Dvashi, H.; Borni, S.; Shaked, R.; Calinsky, R.; Levy, K.; Diskin, R.

10.1101/2024.03.13.584793 — microbiology — Posted on 2024-03-13

2973 The multifunction Coxiella effector Vice stimulates macropinocytosis and interferes with the ESCRT machinery

Bienvenu, A.; Burette, M.; Cantet, F.; Gourdelier, M.; Swain, J. M.; Cazevieille, C.; Clemente, T.; Sadi, A.; Dupont, C.; Le Fe, M.; Bonetto, N.; Bordignon, B.; MURIAUX, D.; Gilk, S. D.; Bonazzi, M.; Martinez, E.

10.1101/2024.03.13.584753 — microbiology — Posted on 2024-03-13

2974 Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

Nahas, K. L.; Connor, V.; Wijesinghe, K. J.; Barrow, H. G.; Dobbie, I. M.; Harkiolaki, M.; Graham, S. C.; Crump, C. M.

10.1101/2024.03.13.584906 — microbiology — Posted on 2024-03-13

2975 Divergent marine anaerobic ciliates harbor closely related Methanocorpusculum endosymbionts

Schrecengost, A.; Polakova, K.; Rotterova, J.; Cepicka, I.; Beinart, R. A.

10.1101/2024.03.12.584670 — microbiology — Posted on 2024-03-13

2976 Searching the Pinus taeda foliar mycobiome for emerging pathogens among brown spot needle blight and needlecast outbreaks in the Southeast United States

Meinecke, C. D.; Niyas, A. M. M.; McCarty, E.; Quesada, T.; Smith, J. A.; Villari, C.

10.1101/2024.03.13.584907 — microbiology — Posted on 2024-03-13

2977 Genetic signatures in the highly virulent subtype B HIV-1 conferring immune escape to V1/V2 and V3 broadly neutralizing antibodies

Marichannegowda, M.; Heredia, A.; Wang, Y.; Song, H.

10.1101/2024.03.13.584899 — microbiology — Posted on 2024-03-13

2978 A vector system for single and tandem expression of cloned genes and multi-colour fluorescent tagging in Haloferax volcanii

Ithurbide, S.; de Silva, R. T.; Brown, H. J.; Shinde, V.; Duggin, I. G.

10.1101/2024.03.13.584740 — microbiology — Posted on 2024-03-13

2979 Root exudation and rhizosphere microbial recruitment are influenced by novel plant trait diversity in carrot genotypes

Anderson, H. M.; Cagle, G. A.; Majumder, E. L.- W.; Silva, E.; Dawson, J.; Simon, P.; Freedman, Z. B.

10.1101/2024.03.12.583384 — microbiology — Posted on 2024-03-13

2980 Tracking inflammation resolution signatures in lungs after SARS-CoV-2 omicron BA.1 infection of K18-hACE2 mice

Carolin, A.; Bishop, C. R.; Yan, K.; Nguyen, W.; Tang, B.; Rawle, D. J.; Suhrbier, A.

10.1101/2024.03.12.584739 — immunology — Posted on 2024-03-13

2981 A bias in transsaccadic perception of spatial frequency changes

Sharvashidze, N.; Hübner, C.; Schütz, A. C.

10.1101/2024.03.11.584439 — neuroscience — Posted on 2024-03-13

2982 Continuous psychophysics shows millisecond-scale visual processing delays are faithfully preserved in movement dynamics

Burge, J.; Cormack, L. K.

10.1101/2020.08.05.238642 — neuroscience — Posted on 2024-03-13

2983 Phosphorylation of PLPPR3 membrane proteins as signaling integrator at neuronal synapses

Kroon, C.; Bareesel, S.; Kirchner, M.; Gimber, N.; Ranti, D.; Brosig, A.; Textoris-Taube, K.; Zolnik, T. A.; Mertins, P.; Schmoranzer, J.; Leondaritis, G.; Eickholt, B. J.

10.1101/2024.03.11.584206 — neuroscience — Posted on 2024-03-13

2984 Theta and alpha oscillations in human hippocampus and medial parietal cortex support the formation of location-based representations

Satish, A.; Keller, V.; Raza, S.; Fitzpatrick, S.; Horner, A. J.

10.1101/2023.10.18.562859 — neuroscience — Posted on 2024-03-13

2985 Chronic Intermittent Hypoxia reveals role of the Postinspiratory Complex in the mediation of normal swallow production

Huff, A. D.; Karlen-Amarante, M.; Oliveira, L. M.; Ramirez, J.-M.

10.1101/2023.09.26.559560 — neuroscience — Posted on 2024-03-13

2986 "The Brain is...": A Survey of The Brain's Many Definitions

Bolt, T. S.; Uddin, L.

10.1101/2023.10.26.564205 — neuroscience — Posted on 2024-03-13

2987 Scalable design of repeat protein structural dynamics via probabilistic coarse-grained models

Sarvaharman, S.; Neary, T. E.; Gorochowski, T. E.; Parmeggiani, F.

10.1101/2024.03.13.584748 — synthetic biology — Posted on 2024-03-13

2988 Host evolution improves genetic circuit function in complex growth environments

Zhang, J. T.; Lezia, A.; Emmanuele, P.; Wu, M.; Olson, C. A.; Feist, A. T.; Hasty, J.

10.1101/2024.03.13.583595 — synthetic biology — Posted on 2024-03-13

2989 Downregulation of NR4A3 During Inactivity Alters Glucose Metabolism and Impairs Translation in Human Skeletal Muscle

Smith, J. A.; Gabriel, B. M.; Krook, A.; Zierath, J. R.; Pillon, N. J.

10.1101/2024.03.11.584422 — physiology — Posted on 2024-03-13

2990 Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling

Zhang, X.; Wu, Y.; Smith, C.; Louch, W. E.; Morotti, S.; Dobrev, D.; Grandi, E.; Ni, H.

10.1101/2024.03.04.583217 — physiology — Posted on 2024-03-13

2991 Non-physiologic interaction of MG53 with insulin receptor and lack of evidence for MG53's role in controlling insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues.

Lee, K. E.; Nishi, M.; Kim, J.; Murayama, T.; Dawson, Z.; Wang, X.; Zhou, X.; Tan, T.; Cai, C.; Takeshima, H.; Park, K. H.

10.1101/2024.01.26.576909 — physiology — Posted on 2024-03-13

2992 AlphaFold2 structures template ligand discovery

Lyu, J.; Kapolka, N.; Gumpper, R.; Alon, A.; Wang, L.; Jain, M.; Alvarez, X.; Sakamoto, K.; Kim, Y.; DiBerto, J.; Kim, K.; Tummino, T.; Huang, S.; Irwin, J.; Tarkhanova, O.; Moroz, Y.; Skiniotis, G.; Kruse, A.; Shoichet, B.; Roth, B.

10.1101/2023.12.20.572662 — pharmacology and toxicology — Posted on 2024-03-13

2993 Silver nanoparticles can be sampled by ultrafiltration probe but elution into & recovery from plasma and DPBS differs in vitro

Risselada, M.; Mc Cain, R. R.; Bates, M. G.; Anderson, M.

10.1101/2024.01.26.577516 — pharmacology and toxicology — Posted on 2024-03-13

2994 Genome-wide association studies in a diverse strawberry collection unveil loci controlling agronomic and fruit quality traits

Munoz, P.; Roldan-Guerra, F. J.; Verma, S.; Ruiz-Velazquez, M.; Torreblanca, R.; Oiza, N.; Castillejo, C.; Sevilla, J. F. S.; Amaya, I.

10.1101/2024.03.11.584394 — plant biology — Posted on 2024-03-13

2995 A novel regulatory pathway recognizes and degrades transcripts with long 3' untranslated regions

Daly, C. W. P.; Kristjansdottir, K.; West, J. D.; Vu, L. T.; Fogarty, E. A.; Geissler, R.; McDermott, C.; Venkataramany, A.; Grimson, A.

10.1101/2024.03.11.584429 — genetics — Posted on 2024-03-13

2996 Comprehensive analysis of RNA-chromatin, RNA- and DNA-protein interactions

Khlebnikov, D. A.; Nikolskaya, A. A.; Zharikova, A. A.; Mironov, A. A.

10.1101/2024.03.13.584417 — bioinformatics — Posted on 2024-03-13

2997 Deoxynivalenol induced inflammation and increased the adherence of entero-invasive Escherichia coli to intestinal epithelial cells via modulation of mucin and pro-inflammatory cytokine production

Wan, M. L.; Co, V. A.; Turner, P. C.; Nagendra, S. P.; El-Nezami, H.

10.1101/2024.03.11.584405 — pharmacology and toxicology — Posted on 2024-03-13

2998 Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting

Shrestha, S.; Lekkala, V. K. R.; Acharya, P.; Kang, S.-Y.; Vanga, M. G.; Lee, M.-Y.

10.1101/2024.03.11.584478 — bioengineering — Posted on 2024-03-13

2999 A Machine Learning-based approach for Simultaneous Electrochemical Detection of Interfering Analytes

Jain, R.; Verma, S.; Dutta, G.

10.1101/2024.03.11.584459 — bioengineering — Posted on 2024-03-13

3000 Environmental DNA as a complementary tool for biodiversity monitoring: A multi-technique and multi-trophic approach to investigate cetacean distribution and feeding ecology

Afonso, L.; Costa, J.; Correia, A. M.; Valente, R.; Lopes, E.; Tomasino, M. P.; Gil, A.; Oliveira-Rodrigues, C.; Sousa-Pinto, I.; Lopez, A.; Magalhaes, C.

10.1101/2024.03.11.584480 — ecology — Posted on 2024-03-13

3001 Coupling hydrodynamic drifting simulations and seasonal demographics to forecast the occurrence of jellyfish blooms

Cant, J.; Jones, O. R.; Ellingson, I.; Laverick, J. H.; Majaneva, S.; Dierking, J.; Aberle, N.; Javidpour, J.

10.1101/2024.03.11.584451 — ecology — Posted on 2024-03-13

3002 Single Cell MALDI-MS Imaging of Lipids and Proteins in Senescent Fibroblasts

Sekera, E. R.; Rosas, L.; Holbrook, J. H.; Angeles, Q. D.; Khaliullin, T.; Rojas, M.; Mora, A. L.; Hummon, A. B.

10.1101/2024.03.13.584140 — biochemistry — Posted on 2024-03-13

3003 PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs

Breidenstein, A.; Lamy, A.; Bader, C. P. J.; Sun, W.-S.; Wanrooij, P. H.; Berntsson, R. P.-A.

10.1101/2024.03.13.584862 — biochemistry — Posted on 2024-03-13

3004 Single-Domain Antibody-Based Protein Degrader for Synucleinopathies

Jiang, Y.; Lin, Y.; Tetlow, A. M.; Pan, R.; Ji, C.; Kong, X.-P.; Congdon, E. E.; Sigurdsson, E. M.

10.1101/2024.03.11.584473 — neuroscience — Posted on 2024-03-13

3005 The gut contractile organoid: a novel model for studying the gut motility regulated by coordinating signals between interstitial cells of Cajal and smooth muscles

Yagasaki, R.; Nakamura, R.; Shikaya, Y.; Tadokoro, R.; Hao, R.; Wang, Z.; Eiraku, M.; Inaba, M.; Takahashi, Y.

10.1101/2024.03.12.584544 — developmental biology — Posted on 2024-03-13

3006 Emotion arousal but not valence is strongly represented in aperiodic EEG activity stemming from thalamocortical interactions

Borah, R. M.; Pathak, A.; Banerjee, A.

10.1101/2024.03.11.584477 — neuroscience — Posted on 2024-03-13

3007 Drosophila appear resistant to trans-synaptic tau propagation

Catterson, J. H.; Mouofo, E. N.; Lopez De Toledo Soler, I.; Lean, G.; Dlamini, S.; Liddell, P.; Voong, G.; Katsinelos, T.; Wang, Y.-C.; Schoovaerts, N.; Verstreken, P.; Spires-Jones, T. L.; Durrant, C. S.

10.1101/2024.03.11.584446 — neuroscience — Posted on 2024-03-13

3008 Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis

Vegting, Y.; Jongejan, A.; Neele, A. E.; Claessen, N.; Sela, G.; Prange, K. H.; Kers, J.; Roelofs, J. J.; van der Heijden, J. W.; de Boer, O. J.; Remmerswaal, E. B.; Vogt, L.; Bemelman, F. J.; de Winther, M. P.; Moerland, P. D.; Hilhorst, M. L.

10.1101/2024.03.13.584866 — immunology — Posted on 2024-03-13

3009 Type I interferon induces TCR-dependent and -independent antimicrobial responses in γδ intraepithelial lymphocytes

Fischer, M. A.; Jia, L.; Edelblum, K. L.

10.1101/2024.03.11.584444 — immunology — Posted on 2024-03-13

3010 Prelimbic cortex perineuronal net expression and social behavior: Impact of adolescent intermittent ethanol exposure

Towner, T.; Coleman, H. J.; Goyden, M. A.; Vore, A. S.; Papastrat, K. M.; Varlinskaya, E. I.; Werner, D. F.

10.1101/2024.03.11.584421 — animal behavior and cognition — Posted on 2024-03-13

3011 Synthesis of geometrically realistic and watertight neuronal ultrastructure manifolds for in silico modeling

Abdellah, M.; Foni, A.; Garcia Cantero, J. J.; Roman Guerrero, N.; Boci, E.; Fleury, A.; Coggan, J. S.; Keller, D.; Planas, J.; Courcol, J.-D.; Khazen, G.

10.1101/2024.03.11.584388 — neuroscience — Posted on 2024-03-13

3012 The Pannexin-1 N-terminal Helix Gates a Switch between Ion Conductance and Anandamide Transport

Anderson, C. L.; Weiilnger, N. L.; Visser, F.; Nielsen, A. C.; Boyce, A. K.; Thompson, R. J.

10.1101/2024.03.11.584466 — neuroscience — Posted on 2024-03-13

3013 Electrophysiological signatures of a developmental delay in a stem cell model of KCNQ2 developmental and epileptic encephalopathy

Rosa, F.; Theiss, S.; Krepp, S.; Loeffler, H.; Mendes, D.; Klingenstein, S.; Liebau, S.; Weckhuysen, S.; Alber, M.; Petrou, S.; Lerche, H.; Maljevic, S.; Wuttke, T. V.

10.1101/2024.03.13.584717 — neuroscience — Posted on 2024-03-13

3014 Individual trajectories for recovery of neocortical activity in disorders of consciousness

Tewarie, P.; Abeysuriya, R.; Panda, R.; Nunez, P.; Vitello, M. M.; van der Lande, G.; Gosseries, O.; Thibaut, A.; Laureys, S.; Deco, G.; Annen, J.

10.1101/2024.03.11.584433 — neuroscience — Posted on 2024-03-13

3015 Impact of Reduced Spectral Resolution on Temporal-Coherence-Based Source Segregation

Viswanathan, V.; Heinz, M. G.; Shinn-Cunningham, B. G.

10.1101/2024.03.11.584489 — neuroscience — Posted on 2024-03-13

3016 Chronic IL-6 overproduction induces a tolerogenic response in aged mice after peripheral nerve injury

Manich, G.; Barbanti, R.; Peris, M.; Villacampa, N.; Almolda, B.; Gonzalez, B.; Castellano, B.

10.1101/2024.03.13.584805 — neuroscience — Posted on 2024-03-13

3017 A brainstem circuit for gravity-guided vertical navigation

Zhu, Y.; Gelnaw, H.; Auer, F.; Hamling, K. R.; Ehrlich, D. E.; Schoppik, D.

10.1101/2024.03.12.584680 — neuroscience — Posted on 2024-03-13

3018 Residual Partial Least Squares Learning: Brain Cortical Thickness Simultaneously Predicts Eight Non-pairwise-correlated Behavioural and Disease Outcomes in Alzheimer's Disease

10.1101/2024.03.11.584383 — neuroscience — Posted on 2024-03-13

3019 Evolutionary double-bind treatment using radiotherapy and NK cell-based immunotherapy in prostate cancer

Luddy, K. A.; West, J.; Robertson-Tessi, M.; Desai, B.; Burrsell, T. M.; Barrett, S.; O'Sullivan, J.; Marignol, L.; Gatenby, R.; Brown, J. S.; Anderson, A. R.; O'Farrelly, C.

10.1101/2024.03.11.584452 — cancer biology — Posted on 2024-03-13

3020 Hi-C profiling in tissues reveals 3D chromatin-regulated breast tumor heterogeneity and tumor-specific looping-mediated biological pathways

Choppavarapu, L.; Fang, K.; Liu, T.; Jin, V. X.

10.1101/2024.03.13.584872 — cancer biology — Posted on 2024-03-13

3021 Two-photon excitation two-dimensional fluorescence spectroscopy (2PE-2DFS) of the fluorescent nucleobase 6-MI

Albrecht, C. S.; Scatena, L. F.; von Hippel, P. H.; Marcus, A. H.

10.1101/2024.03.13.584863 — biophysics — Posted on 2024-03-13

3022 RevGraphVAMP: A protein molecular simulation analysis model combining graph convolutional neural networks and physical constraints

Huang, Y.; Zhang, H.; Lin, Z.; Wei, Y.; Xi, W.

10.1101/2024.03.11.584426 — bioinformatics — Posted on 2024-03-13

3023 Expanding and enriching the LncRNA gene landscape using the GeneCaRNA database

Aggarwal, S.; Rosenblum, C.; Gould, M.; Ziman, S.; Barshir, R.; Zelig, O.; Golan, Y. G.; Iny-Stein, T.; Safran, M.; Pietrokovski, S.; Lancet, D.

10.1101/2024.03.11.584435 — bioinformatics — Posted on 2024-03-13

3024 Wild lytic bacteriophages: a potential enhancer of disinfectants biofilm inhibition in bio-industrial settings for fruit fly production.

Matute Torres, J. R.; Linares Fernandez, M.; Rendon, P.; Pennington, P. M.

10.1101/2024.03.11.584479 — bioengineering — Posted on 2024-03-13

3025 Time-resolved oxidative signal convergence across the algae-embryophyte divide

Rieseberg, T. P.; Dadras, A.; Darienko, T.; Post, S.; Herrfurth, C.; Fuerst-Jansen, J. M.; Hohnhorst, N.; Petroll, R.; Rensing, S. A.; Proeschold, T.; de Vries, S.; Irisarri, I.; Feussner, I.; de Vries, J.

10.1101/2024.03.11.584470 — evolutionary biology — Posted on 2024-03-13

3026 "This training is bound for glory": selection by experimental evolution of a bacteriophage with expanded host-range and increased virulence

Maurin, A.; Vasse, M.; Zarate-Chaves, C.; breyton, C.; Bouzidi, S.; hayer, J.; Dainat, J.; Mesleard-Roux, M.; Weill, F.-X.; Bravo, I. G.; Feugier, A.; Froissart, R.

10.1101/2024.03.13.584857 — evolutionary biology — Posted on 2024-03-13

3027 Seasonal structural stability promoted by forest diversity and composition explains overyielding

Guzman Q., J. A.; Park, M. H.; Williams, L. J.; Cavender-Bares, J.

10.1101/2024.03.11.584423 — ecology — Posted on 2024-03-13

3028 Chemical inhibition of the integrated stress response impairs the ubiquitin-proteasome system

Xu, S.; Gierisch, M. E.; Barchi, E.; Poser, I.; Alberti, S.; Salomons, F. A.; Dantuma, N. P.

10.1101/2024.03.13.584747 — cell biology — Posted on 2024-03-13

3029 Bacterial RNA promotes proteostasis through inter-tissuecommunication in C. elegans

Kyriakakis, E.; Medde, C.; Ritz, D.; Fucile, G.; Schmidt, A.; Spang, A.

10.1101/2024.03.13.584467 — cell biology — Posted on 2024-03-13

3030 Toward generalizable phenotype prediction from single-cell morphology representations

Tomkinson, J.; Kern, R.; Mattson, C.; Way, G. P.

10.1101/2024.03.13.584858 — cell biology — Posted on 2024-03-13

3031 SuperResNET single molecule localization microscopy model-free network analysis of Nup96 achieves molecular resolution

Li, Y. L.; Khater, I. M.; Hallgrimson, C.; Cardoen, B.; Wong, T. H.; Hamarneh, G.; Nabi, I. R.

10.1101/2024.03.12.584716 — cell biology — Posted on 2024-03-13

3032 Use of Mucosally Administered Outer Membrane Vesicles Derived from Bordetella pertussis to Diminish Nasal Bacterial Colonization

Rudi, E.; Gaillard, M. E.; Bottero, D.; Hozbor, D.

10.1101/2024.03.11.584448 — immunology — Posted on 2024-03-13

3033 Cellular and circuit mechanisms underlying binocular vision

Honnuraiah, S.; Huang, H. H.- Y.; Ryan, W. J.; Broersen, R.; Connelly, W. M.; Stuart, G.

10.1101/2024.03.11.584536 — neuroscience — Posted on 2024-03-13

3034 The Kv2.2 channel mediates the inhibition of Prostaglandin E2 on glucose-stimulated insulin secretion in pancreatic β/-cells

Pan, C.; Liu, Y.; Wang, L.; Fan, W.-Y.; Ni, Y.; Zhang, X.; Wu, D.; Li, C.; Li, J.; Li, Z.; Liu, R.; Hu, C.

10.1101/2024.03.11.584397 — physiology — Posted on 2024-03-13

3035 Karanjin alters gene expression through ERα: a preliminary study

Bhatt, G.; Rangan, L.; Limaye, A. M.

10.1101/2024.03.11.584382 — pharmacology and toxicology — Posted on 2024-03-13

3036 The genomic trajectory of ovarian high grade serous carcinoma is determined in STIC lesions

Cheng, Z.; Ennis, D. P.; Lu, B.; Mirza, H. B.; Sokota, C.; Kaur, B.; Singh, N.; Le Saux, O.; Russo, G.; Giannone, G.; Tookman, L. A.; Krell, J.; McDermott, J.; Barnes, C.; McNeish, I. A.

10.1101/2024.03.11.584384 — cancer biology — Posted on 2024-03-13

3037 A metastasis-associated Pannexin1 mutant (Panx11-89) forms a minimalist ATP release channel

Wang, J.; Mim, C.; Dahl, G.; Barro-Soria, R.

10.1101/2024.03.12.584732 — biophysics — Posted on 2024-03-13

3038 Multiomics Analysis Reveals Extensive Remodeling of the Extracellular Matrix and Cellular Metabolism Due to Plakophilin-2 Knockdown in Guinea Pigs

Song, R.; Wu, H.; Yu, L.; Yu, J.; yang, W.; Wu, W.; Sun, F.; Wang, H.

10.1101/2024.03.11.584401 — genetics — Posted on 2024-03-13

3039 eATP/P2X7R axis drives nanoparticle induced neutrophil recruitment in the pulmonary microcirculation

Li, C.; Liu, Q.; Han, L.; Immler, R.; Rathkolb, B.; Secklehner, J.; Hrabe de Angelis, M.; Yildirim, A. O.; Nicke, A.; Carlin, L. M.; Sperandio, M.; Stoeger, T.; Rehberg, M.

10.1101/2024.03.11.584398 — immunology — Posted on 2024-03-13

3040 Analysis of higher order interactions quantifies co-ordination in the epigenome and reveals novel biological relationships in Kabuki syndrome

Cuvertino, S.; Garner, T.; Martirosian, E.; Walusimbi, B.; Kimber, S. J.; Banka, S.; Stevens, A.

10.1101/2024.03.11.584387 — systems biology — Posted on 2024-03-13

3041 Setting Climate Targets: The Case of Higher Education and Research

Ligozat, A.-L.; Brun, C.; Demirdjian, B.; Gouget, G.; Jarde, E.; Mialon, A.; Mouronval, A.-S.; Pagani, L.; Vieu, L.

10.1101/2024.03.11.584380 — scientific communication and education — Posted on 2024-03-13

3042 Separate domains of the Arabidopsis ENHANCER OF PINOID drive its own polarization and recruit PIN1 to the plasma membrane

Torres, R.; Matthes, M.; Yun, N.; Luichtl, M.; Büschges, U.; Fiesselmann, B.; Strickland, B.; Lehnardt, M.

10.1101/2024.03.11.584374 — plant biology — Posted on 2024-03-13

3043 Large gradient of susceptibility to esca disease revealed by long-term monitoring of 46 grapevine cultivars in a common garden vineyard

Gastou, P.; Destrac Irvine, A.; Arcens, C.; Courchinoux, E.; This, P.; van Leeuwen, C.; Delmas, C. E. L.

10.1101/2024.03.11.584376 — plant biology — Posted on 2024-03-13

3044 A neurometabolic signature in the frontal cortex predicts individual differences in effort-based decision-making

Barakat, A.; Clairis, N.; Brochard, J.; Pessiglione, M.; Godin, J.-P.; Cuenoud, B.; Xin, L.; Sandi, C.

10.1101/2024.01.23.576854 — neuroscience — Posted on 2024-03-13

3045 Spatial interactions modulate tumor growth and immune infiltration

Marzban, S.; Srivastava, S.; Kartika, S.; Bravo, R.; Safriel, R.; Zarski, A.; Anderson, A. R. A.; Chung, C. H.; Amelio, A. L.; West, J.

10.1101/2024.01.10.575036 — cancer biology — Posted on 2024-03-13

3046 Self-organisation of mortal filaments: the role of FtsZ treadmilling in bacterial division ring formation

Vanhille Campos, C.; Whitley, K. D.; Radler, P.; Loose, M.; Holden, S.; Saric, A.

10.1101/2023.05.08.539808 — biophysics — Posted on 2024-03-13

3047 Improving dictionary-based named entity recognition with deep learning

Nastou, K.; Koutrouli, M.; Pyysalo, S.; Jensen, L. J.

10.1101/2023.12.10.570777 — bioinformatics — Posted on 2024-03-13

3048 Changes in total charge on spike protein of SARS-CoV-2 in emerging lineages

Bozic, A.; Podgornik, R.

10.1101/2023.10.21.563433 — bioinformatics — Posted on 2024-03-13

3049 Sexual antagonism and sex determination in three syngnathid species alongside male pregnancy gradient and varying sex roles.

Dubin, A.; Parker, J.; Boehne, A.; Roth, O.

10.1101/2023.08.30.555491 — evolutionary biology — Posted on 2024-03-13

3050 Fixation times of de novo and standing beneficial variants in subdivided populations

Sudbrack, V.; Mullon, C.

10.1101/2023.07.07.548167 — evolutionary biology — Posted on 2024-03-13

3051 Target-agnostic identification of human antibodies to Plasmodium falciparum sexual forms reveals cross stage recognition of glutamate-rich repeats

Amen, A.; Yoo, R.; Fabra-Garcia, A.; Bolscher, J.; Stone, W. J. R.; Bally, I.; Dergan-Dylon, S.; Kucharska, I.; de Jong, R. M.; de Bruijni, M.; Bousema, T.; King, C. R.; MacGill, R. S.; Sauerwein, R. W.; Julien, J.-P.; Poignard, P.; Jore, M. M.

10.1101/2023.11.03.565335 — immunology — Posted on 2024-03-13

3052 BOLD Moments: modeling short visual events through a video fMRI dataset and metadata

Lahner, B.; Dwivedi, K.; Iamshchinina, P.; Graumann, M.; Lascelles, A.; Roig, G.; Gifford, A. T.; Pan, B.; Jin, S.; Ratan Murty, N. A.; Kay, K.; Oliva, A.; Cichy, R.

10.1101/2023.03.12.530887 — neuroscience — Posted on 2024-03-13

3053 Acoustic inspired brain-to-sentence decoder for logosyllabic language

Feng, C.; Cao, L.; Wu, D.; Zhang, E.; Wang, T.; Jiang, X.; Zhou, C.; Chen, J.; Wu, H.; Lin, S.; Hou, Q.; Yang, J.; Lin, C.-T.; Zhu, J.; Sawan, M.; Zhang, Y.

10.1101/2023.11.05.562313 — neuroscience — Posted on 2024-03-13

3054 Widefield in vivo imaging system with two fluorescence and two reflectance channels, a single sCMOS detector, and shielded illumination

Doran, P. R.; Fomin-Thunemann, N.; Tang, R. P.; Balog, D.; Zimmerman, B.; Kilic, K.; Martin, E. A.; Kura, S.; Fisher, H. P.; Chabbott, G.; Herbert, J.; Rauscher, B. C.; Jiang, J. X.; Sakadzic, S.; Boas, D. A.; Devor, A.; Chen, I. A.; Thunemann, M.

10.1101/2023.11.07.566086 — neuroscience — Posted on 2024-03-13

3055 Environmental and genetic influence on rate and spectrum of spontaneous mutations in Escherichia coli

Gifford, D. R.; Bhattacharyya, A.; Geim, A.; Marshall, E.; Krasovec, R.; Knight, C. G.

10.1101/2023.04.06.535897 — evolutionary biology — Posted on 2024-03-13

3056 Spatial distribution of poultry farms using point pattern modelling: a method to address livestock environmental impacts and disease transmission risks

Dupas, M.-C.; Pinotti, F.; Joshi, C.; Joshi, M.; Blake, D.; Tomley, F.; Gilbert, M.; Fournie, G.

10.1101/2024.03.11.584368 — bioinformatics — Posted on 2024-03-13

3057 Repeatability of an extended phenotype: causes and consequences of nest variation in a free-living songbird

Carr, C. E. G.; Swanson, Z. M.; Reichard, D. G.

10.1101/2024.03.08.584149 — animal behavior and cognition — Posted on 2024-03-13

3058 NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing

Kulkarni, O. V.; Zaveri, L.; Singh, N. K.; Mathew, R. J.; Ara, S.; Garde, S.; Reddy, M.; Tallapaka, K. B.; Sowpati, D. T.

10.1101/2024.03.12.584205 — genomics — Posted on 2024-03-13

3059 Copy number variants underlie the major selective sweeps in insecticide resistance genes in Anopheles arabiensis from Tanzania.

Lucas, E. R.; Nagi, S. C.; Kabula, B.; Batengana, B.; Kisinza, W.; Egyir-Yawson, A.; Essandoh, J.; Dadzie, S.; Chabi, J.; Van't Hof, A. E.; Rippon, E. J.; Pipini, D.; Harding, N. J.; Dyer, N. A.; Clarkson, C. S.; Miles, A.; Weetman, D.; Donnelly, M. J.

10.1101/2024.03.11.583874 — genomics — Posted on 2024-03-13

3060 Dissection of core promoter syntax through single nucleotide resolution modeling of transcription initiation

He, A. Y.; Danko, C. G.

10.1101/2024.03.13.583868 — genomics — Posted on 2024-03-13

3061 Identification of novel myelodysplastic syndromes prognostic subgroups by integration of inflammation, cell-type composition, and immune signatures in the bone marrow

Gerlevik, S.; Hama, S.; Seymen, N.; Mumtaz, W.; Thompson, I. R.; Jalili, S. R.; Kaya, D. E.; Iacoangeli, A.; Pellagatti, A.; Boultwood, J.; Napolitani, G.; Mufti, G. J.; Karimi, M. M.

10.1101/2024.03.11.584361 — genomics — Posted on 2024-03-13

3062 NLRP3 and AIM2 inflammasomes exacerbate the pathogenic Th17 cell response to eggs of the helminth Schistosoma mansoni

Suresh Kumar Meena Kumari, M.; Liu, P.; Jump, K.; Morales, Y.; Miller, E. A.; Shecter, I.; Stadecker, M. J.; Kalantari, P.

10.1101/2024.03.11.584371 — immunology — Posted on 2024-03-13

3063 CRISPR/Cas9-mediated deletion of a kinetoplast-associated gene attenuates virulence in Leishmania major parasites

Darzi, F.; Khamesipour, A.; Bahrami, M.; Nateghi Rostami, M.

10.1101/2024.03.11.584372 — immunology — Posted on 2024-03-13

3064 Hemispheric multi-dimension features extraction analysis based on decoupled representation learning

Su, Y.; Wang, S.; Zhang, X.; Lan, M.; Zhong, S.

10.1101/2024.03.13.584299 — neuroscience — Posted on 2024-03-13

3065 Postmortem evidence of microglial involvement in the child abuse-associated increase of perineuronal nets in the ventromedial prefrontal cortex

Belliveau, C.; Rahimian, R.; Fakhfouri, G.; Davoli, M. A.; Giros, B.; Turecki, G.; Mechawar, N.

10.1101/2024.03.08.584135 — neuroscience — Posted on 2024-03-13

3066 Construction of invariant features for time-domain EEG/MEG signals using Grassmann manifolds

Hindriks, R.; Rot, T. O.; Tewarie, P.; van Putten, M. J. A. M.

10.1101/2024.03.11.584366 — neuroscience — Posted on 2024-03-13

3067 Autoimmune antibody-induced neuronal hyperactivity triggers pathological Tau in IgLON5 disease

Askin, B.; Cordero Gomez, C.; Duong, S. L.-L.; Kilic, C.; Goihl, A.; Newman, A.; Wagner, J.; Thomas, V.; Lamberty, J.; Huebschmann, S.; Semenova, E.; Koertvelyessy, P.; Reinhold, D.; Kornau, H.-C.; Turko, P.; Neher, J. J.; Schmitz, D. G.; Rost, B. R.; Diez, L.; Pruess, H.; Wegmann, S.

10.1101/2024.03.10.584272 — neuroscience — Posted on 2024-03-13

3068 Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomato

Vu, T. V.; Nguyen, N. T.; Kim, J.; Vu, M. H.; Song, Y. J.; Tran, M. T.; Sung, Y. W.; Kim, J.-Y.

10.1101/2024.03.12.584635 — plant biology — Posted on 2024-03-13

3069 Transcriptional Regulation of Protein Synthesis by Mediator Kinase in MYC-driven Medulloblastoma

Wang, D.; Ritz, C.; Pierce, A.; Brunt, B.; Luo, Y.; Dahl, N.; Venkataraman, S.; Danis, E.; Kus, K.; Mazan, M.; Rzymski, T.; Veo, B.; Vibhakar, R.

10.1101/2024.03.08.584103 — cancer biology — Posted on 2024-03-13

3070 NLRP3-induced systemic inflammation controls the development of JAK2V617F mutant myeloproliferative neoplasms

Koerber, R.-M.; Krollmann, C.; Cieslak, K.; Tregel, E.; Brümmendorf, T. H.; Koschmieder, S.; Griesshammer, M.; Gütgemann, I.; Brossart, P.; Skoda, R.; Kolbe, C. C.; Latz, E.; Wolf, D.; Teichmann, L. L.

10.1101/2024.03.09.583936 — cancer biology — Posted on 2024-03-13

3071 Determining Optimal Placement of Copy Number Aberration Impacted Single Nucleotide Variants in a Tumor Progression History

Wu, C. H.; Joshi, S.; Robinson, W.; Robbins, P. F.; Schwartz, R.; Sahinalp, C.; Malikic, S.

10.1101/2024.03.10.584318 — cancer biology — Posted on 2024-03-13

3072 PRMT5 maintains tumor stem cells to promote pediatric high-grade glioma tumorigenesis

DeSisto, J.; Balakrishnan, I.; Knox, A.; Link, G.; Venkataraman, S.; Vibhakar, R.; Green, A. L.

10.1101/2024.03.12.583794 — cancer biology — Posted on 2024-03-13

3073 Controlled Protein-Membrane Interactions Regulate Self-Organization of Min Protein Patterns

Hasani, M.; Esch, K.; Zieske, K.

10.1101/2024.03.13.584081 — biophysics — Posted on 2024-03-13

3074 A Mixed Effect Similarity Matrix Regression Model (SMRmix) for Integrating Multiple Microbiome Datasets at Community Level and its Application in HIV

He, M.; Zhao, N.

10.1101/2024.03.10.584315 — bioinformatics — Posted on 2024-03-13

3075 CatPred: A comprehensive framework for deep learning in vitro enzyme kinetic parameters kcat, Km and Ki

Boorla, V. S.; Maranas, C. D.

10.1101/2024.03.10.584340 — bioinformatics — Posted on 2024-03-13

3076 Geometric deep learning framework for de novo genome assembly

Vrcek, L.; Bresson, X.; Laurent, T.; Schmitz, M.; Kawaguchi, K.; Sikic, M.

10.1101/2024.03.11.584353 — bioinformatics — Posted on 2024-03-13

3077 Effectiveness and efficiency: label-aware hierarchical subgraph learning for protein-protein interaction (laruGL-PPI)

Zhou, Y.; Lin, H.; Huang, Y.; Wu, L.; Li, S. Z.

10.1101/2024.03.08.584199 — bioinformatics — Posted on 2024-03-13

3078 Benchmarking clustering, alignment, and integration methods for spatial transcriptomics

Hu, Y.; Li, Y.; Xie, M.; Rao, M.; Shen, W.; Luo, C.; Qin, H.; Baek, J.; Zhou, X. M.

10.1101/2024.03.12.584114 — bioinformatics — Posted on 2024-03-13

3079 playOmics: A multi-omics pipeline for interpretable predictions and biomarker discovery

Glowacka-Walas, J.; Sijko, K.; Wojdan, K.; Gambin, T. L.

10.1101/2024.03.12.584088 — bioinformatics — Posted on 2024-03-13

3080 Uncovering disease-related multicellular pathway modules on large-scale single-cell transcriptomes with scPAFA

Huang, Z.; Zheng, Y.; Wang, W.; Zhou, W.; Wei, C.; Zhang, X.; Jin, X.; Yin, J.

10.1101/2024.03.11.584023 — bioinformatics — Posted on 2024-03-13

3081 Ongoing hybridisation among clownfishes: the genomic architecture of the Kimbe Bay hybrid zone

Schmid, S.; Hartasanchez, D. A.; Gainsford, A.; Jones, G.; Salamin, N.

10.1101/2024.03.10.584293 — evolutionary biology — Posted on 2024-03-13

3082 Freshwater fish egg dispersal by attaching to waterbirds

Yao, A.; Mashiko, M.; Toquenaga, Y.

10.1101/2024.03.11.584339 — ecology — Posted on 2024-03-13

3083 Neuroprotective role of Hippo signaling by microtubule stability control in C. elegans

Lee, H.; Kang, J.; Lee, D.; Lee, S.-H.; Chung, C. H.; Lee, J.

10.1101/2024.03.11.584363 — developmental biology — Posted on 2024-03-13

3084 Post-embryonic tail development through molting of the freshwater shrimp Neocaridina denticulata

Adachi, H.; Moritoki, N.; Shindo, T.; Arakawa, K.

10.1101/2024.03.13.583832 — developmental biology — Posted on 2024-03-13

3085 Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells

Rosa, F.; Dray, N.; Bally-Cuif, L.

10.1101/2024.03.09.584233 — developmental biology — Posted on 2024-03-13

3086 Astrocytes control quiescent NSC reactivation via GPCR signaling-mediated F-actin remodeling

Lin, K.-Y.; Mahekta, G.; Lin, J.; Ding, W. Y.; Huang, J.; Gao, Y.; Tan, Y. S.; Teng, X.; Low, S. L. C.; Kanchanawong, P.; Toyama, Y.; Wang, H.

10.1101/2024.03.11.584337 — developmental biology — Posted on 2024-03-13

3087 Tumor microenvironment immunomodulation by nanoformulated TLR 7/8 agonist and PI3k delta inhibitor enhances therapeutic benefits of radiotherapy

Yazdimamaghani, M.; Kolupaev, O.; Lim, C.; Hwang, D.; Laurie, S.; Perou, C.; Kabanov, A.; Serody, J.

10.1101/2024.03.09.584084 — immunology — Posted on 2024-03-13

3088 CB1 Cannabinoid Receptor Agonists Induce Acute Respiratory Depression in Awake Mice

Watkins, J. M.; Aradi, P.; Hahn, R.; Makriyannis, A.; Mackie, K.; Katona, I.; Hohmann, A. G.

10.1101/2024.03.12.584260 — neuroscience — Posted on 2024-03-13

3089 The Compensatory Mechanism of the Prefrontal Cortex in Preserving Speech-in-Noise Comprehension Among Older Adults

Li, Z.; Liu, Y.; Zhang, X.; Kou, N.; Zhao, X.; Jiang, X.; Zhang, D.; Wang, S.

10.1101/2024.03.08.584193 — neuroscience — Posted on 2024-03-13

3090 Low-intensity focused ultrasound to the human insular cortex differentially modulates the heartbeat-evoked potential: a proof-of-concept study

Strohman, A.; Payne, B.; Isaac, G.; Verdonk, C.; Khalsa, S. S.; Legon, W.

10.1101/2024.03.08.584152 — neuroscience — Posted on 2024-03-13

3091 Heterogeneity of layer 4 in visual areas of rhesus macaque cortex

Guenther, D. M.; Batiuk, M. Y.; Petukhov, V.; De Oliveira, R.; Wunderle, T.; Buchholz, C. J.; Fries, P.; Khodosevich, K.

10.1101/2024.03.11.584345 — neuroscience — Posted on 2024-03-13

3092 REST and RCOR genes display distinct expression profiles in neurons and astrocytes using 2D and 3D human pluripotent stem cell models

Maksour, S.; Ng, N.; Hulme, A. J.; Miellet, S.; Engel, M.; Sanz Munoz, S.; Balez, R.; Rollo, B.; Finol-Urdaneta, R. K.; Ooi, L.; Dottori, M.

10.1101/2024.03.09.584254 — neuroscience — Posted on 2024-03-13

3093 Bayesian Optimization of Neurostimulation (BOONStim)

Oliver, L. D.; Jeyachandra, J.; Dickie, E. W.; Hawco, C.; Mansour, S.; Buchanan, R. W.; Malhotra, A. K.; Blumberger, D. M.; Deng, Z.-D.; Voineskos, A. N.

10.1101/2024.03.08.584169 — neuroscience — Posted on 2024-03-13

3094 Physiological correlates of a simple saccadic-decision task in superior colliculus

Caziot, B.; Cooper, B.; Harwood, M. R.; McPeek, R. M.

10.1101/2024.03.09.584223 — neuroscience — Posted on 2024-03-13

3095 Enhanced Place Specificity of the Parallel Auditory Brainstem Response: An Electrophysiology Study

Stoll, T. J.; Maddox, R. K.

10.1101/2024.03.10.584313 — neuroscience — Posted on 2024-03-13

3096 Effective connectivity predicts distributed neural coding of perceptual decision confidence, uncertainty and speed

Asadpour, A.; Wong-Lin, K.

10.1101/2024.03.09.584217 — neuroscience — Posted on 2024-03-13

3097 Dissociable representations of decision variables within subdivisions of macaque orbitofrontal and ventrolateral frontal cortex

Stoll, F. M.; Rudebeck, P. H.

10.1101/2024.03.10.584181 — neuroscience — Posted on 2024-03-13

3098 Presynaptic occlusion of long lasting NMDAR-dependent potentiation in Synaptophysin family knockouts

del Olmo, S.; Rodriguez Gotor, J. J.; Wesseling, J.

10.1101/2024.03.12.583943 — neuroscience — Posted on 2024-03-13

3099 Dopaminergic signaling regulates microglial surveillance and adolescent plasticity in the frontal cortex.

Stowell, R. D.; Wang, K. H.

10.1101/2024.03.08.584167 — neuroscience — Posted on 2024-03-13

3100 Association between gene expression plasticity and regulatory network topology

Petit, A. J. R.; Genissel, A.; Le Rouzic, A.

10.1101/2024.03.11.584403 — systems biology — Posted on 2024-03-13

3101 Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting

Steinbrecht, D.; Minia, I.; Milek, M.; Meisig, J.; Bluethgen, N.; Landthaler, M.

10.1101/2024.03.11.584215 — systems biology — Posted on 2024-03-13

3102 Navigated range expansion promotes migratory culling

Zhang, Y.; Hu, Q.; Su, Y.; Chu, P.; Wei, T.; Yu, P.; Liu, C.; Fu, X.

10.1101/2024.03.09.584265 — systems biology — Posted on 2024-03-13

3103 Deepening biomedical research training: Community-Building Wellness Workshops for Post-Baccalaureate Research Education Program (PREP) Trainees

Cole, D.; Eneim, A. S.; White, C. J.; Eddings, C. R.; Beckett, M. Q.; Clark, V.; Jeffery, J.; Wimalasena, V. K.; Figueroa, A.; Rosado-Franco, J. J.; Alhariri, R.; Powell, B. H.; Washington, P. W.; Christensen, L. N.; Wilson, K. L.; Kavran, J. M.

10.1101/2024.03.10.584300 — scientific communication and education — Posted on 2024-03-13

3104 Genome-Wide Identification of G-Quadruplex forming regions in Arabidopsis: Unraveling the Role of Pif like Helicase (AtPLH1) in Gene Regulation and Stress Response

Singh, S.; Singh, S.; Gupta, K.; Sharma, H.; Bady, S.; Sondhi, M.; Garg, R.

10.1101/2024.03.11.584348 — plant biology — Posted on 2024-03-13

3105 De novo genome assembly of Myricaria laxiflora provides insights into its molecular mechanisms under flooding stress

Weibo, X.; Linbao, L.; Guiyun, H.; Bicheng, D.; Huiyuan, C.; Xiaobo, M.; Haibo, Z.; Zhiqiang, X.; Jihong, L.; Zhen, Y.; Di, W.

10.1101/2024.03.09.584251 — plant biology — Posted on 2024-03-13

3106 Growth arrest is a DNA damage protection strategy in plants

Serrano-Mislata, A.; Hernandez-Garcia, J.; de Ollas, C.; Blanco-Tourinan, N.; Gomez-Cadenas, A.; Sablowski, R.; Alabadi, D.; Blazquez, M. A.

10.1101/2024.03.12.584648 — plant biology — Posted on 2024-03-13

3107 An array of Zymoseptoria tritici effectors suppress plant immune responses

Thynne, E.; Ali, H.; Seong, K.; Abukhalaf, M.; Guerreiro, M. A.; Flores-Nunez, V. M.; Hansen, R.; Salman, M.; Rudd, J. J.; Kanyuka, K.; Krasileva, K. V.; Kettles, G. J.; Stukenbrock, E. H.

10.1101/2024.03.12.584321 — plant biology — Posted on 2024-03-13

3108 Why the adventitious roots of poplar are so colorful: RNAseq and metabolomic analysis reveal flavonols, flavones, and anthocyanins accumulation in canker pathogens-induced adventitious roots in poplar

Min, L.; Yuchen, F.; Jinxin, L.; Wanna, S.; Li, W.; Zheng, L.; Shiqi, Z.; Huixiang, L.; Xiaohua, S.; Jiaping, Z.

10.1101/2024.03.09.584208 — plant biology — Posted on 2024-03-13

3109 Metabolomic analysis of the effect of endocannabinoid metabolism inhibition in ovalbumin-induced allergic airway inflammation in Guinea pigs

Abohalaka, R.; Karaman, Y.; Recber, T.; Onder, S. C.; Nemutlu, E.; Bozkurt, T. E.

10.1101/2024.03.10.584309 — pharmacology and toxicology — Posted on 2024-03-13

3110 Reduction in activity and abundance of mitochondrial electron transport chain supercomplexes in pulmonary hypertension-induced right ventricular dysfunction

Ma, W.; Zhang, P.; Vang, A.; Zimmer, A.; Huck, S.; Nicely, P.; Wang, E.; Mancini, T. J.; Owusu-Sarfo, J.; Cavarsan, C. F.; Belyvech, A. E.; Campbell, K. S.; Terentyev, D.; Choudhary, G.; Clements, R. T.

10.1101/2024.03.08.584016 — pathology — Posted on 2024-03-13

3111 Spatially heterogeneous responses of planktonic foraminifera assemblages over 700,000 years of climate change

Mathes, G. H.; Reddin, C.; Kiessling, W.; Antell, G. S.; Saupe, E. E.; Steinbauer, M. J.

10.1101/2024.03.08.584139 — paleontology — Posted on 2024-03-13

3112 Advancements in Cardiovascular Disease Detection: Leveraging Data Mining and Machine Learning

Hossain, M. S.; Talukder, M. A.; Mahmud, M. Z.

10.1101/2024.03.09.584222 — cancer biology — Posted on 2024-03-13

3113 Epigenetic Reprogramming of Autophagy Drives Mutant IDH1 Glioma Progression and Response to Radiation

NUNEZ, F. J.; Banerjee, K.; Mujeeb, A. A.; Mauser, A.; Tronrud, C. E.; Zhu, Z.; Taher, A.; Kadiyala, P.; Carney, S. V.; Garcia-Fabiani, M. B.; Comba, A.; Alghamri, M. S.; McClellan, B. L.; Faisal, S. M.; Nwosu, Z. C.; Hong, H. S.; Qin, T.; Sartor, M. A.; Ljungman, M.; Cheng, S.-Y.; Appelman, H. D.; Lowenstein, P. R.; Lahann, J.; Lyssiotis, C. A.; Castro, M.

10.1101/2024.03.08.584091 — cancer biology — Posted on 2024-03-13

3114 A Mem-dELISA platform for dual color and ultrasensitive digital detection of colocalized proteins on extracellular vesicles

Sharma, H.; Yadav, V.; Burchett, A.; Shi, T.; Senapati, S.; Datta, M.; Chang, H.-C.

10.1101/2024.03.10.584311 — cancer biology — Posted on 2024-03-13

3115 ADRA2A promotes the classical/progenitor subtype and reduces disease aggressiveness of pancreatic cancer

Moreno, P.; Ohara, Y.; Craig, A. J.; Liu, H.; Yang, S.; Zhang, L.; Panigrahi, G.; Dorsey, T. H.; Cawley, H.; Azizian, A.; Gaedcke, J.; Ghadimi, M.; Hanna, N.; Hussain, S. P.

10.1101/2024.03.12.584316 — cancer biology — Posted on 2024-03-13

3116 Magnetic particle imaging reveals that iron-labeled extracellular vesicles accumulate in brains of mice with metastases

Toomajian, V. A.; Tundo, A.; Ural, E. E.; Greeson, E. M.; Contag, C. H.; Makela, A. V.

10.1101/2024.03.12.584146 — cancer biology — Posted on 2024-03-13

3117 BET inhibitors as a therapeutic intervention in gastrointestinal gene signature-positive castration-resistant prostate cancer.

Shukla, S.; Li, D.; Nguyen, H.; Conner, J.; Bayshtok, G.; Cho, W. H.; Pachai, M.; Teri, N.; Campeau, E.; Attwell, S.; Trojer, P.; Ostrovnaya, I.; Gopalan, A.; Corey, E.; Chi, P.; Chen, Y.

10.1101/2024.03.09.584256 — cancer biology — Posted on 2024-03-13

3118 A knockoff calibration method to avoid over-clustering in single-cell RNA-sequencing

DenAdel, A.; Ramseier, M. L.; Navia, A. W.; Shalek, A. K.; Raghavan, S.; Winter, P. S.; Amini, A. P.; Crawford, L.

10.1101/2024.03.08.584180 — bioinformatics — Posted on 2024-03-13

3119 Integrating data from across insecticide resistance bioassay types using a mechanistic model incorporating mosquito genetic variation and behaviour

Denz, A.; Kont, M. D.; Sanou, A.; Churcher, T. S.; Lambert, B.

10.1101/2024.03.09.584248 — bioinformatics — Posted on 2024-03-13

3120 Automated Identification of Germline de novo Mutations in Family Trios: A Consensus-Based Informatic Approach

Shadrina, M.; Kalay, O.; Demirkaya-Budak, S.; LeDuc, C. A.; Chung, W. K.; Turgut, D.; Budak, G.; Arslan, E.; Semenyuk, V.; Davis-Dusenbery, B.; Seidman, C. E.; Yost, H. J.; Jain, A.; Gelb, B. D.

10.1101/2024.03.08.584100 — bioinformatics — Posted on 2024-03-13

3121 CytoSignal Detects Locations and Dynamics of Ligand-Receptor Signaling at Cellular Resolution from Spatial Transcriptomic Data

Liu, J.; Manabe, H.; Qian, W.; Wang, Y.; Gu, Y.; Chu, A. K. Y.; Gadhvi, G.; Song, Y.; Ono, N.; Welch, J. D.

10.1101/2024.03.08.584153 — bioinformatics — Posted on 2024-03-13

3122 A Spatial Omnibus Test (SPOT) for Spatial Proteomic Data

Samorodnitsky, S. N.; Campbell, K. M.; Ribas, A.; Wu, M. C.

10.1101/2024.03.08.584117 — bioinformatics — Posted on 2024-03-13

3123 Graph Contrastive Learning of Subcellular-resolution Spatial Transcriptomics Improves Cell Type Annotation and Reveals Critical Molecular Pathways

Lu, Q.; Ding, J.; Li, L.; Chang, Y.; Tang, J.; Qiu, X.

10.1101/2024.03.08.584192 — bioinformatics — Posted on 2024-03-13

3124 HemaCisDB: An Interactive Database for Analyzing Cis-Regulatory Elements Across Hematopoietic Malignancies

Cai, X.; Zhang, Q.; Liu, B.; Sun, L.; Liu, Y.

10.1101/2024.03.12.583848 — bioinformatics — Posted on 2024-03-13

3125 Detection of spatial chromatin accessibility patterns with inter-cellular correlations

Chen, X.; Li, K.; Jiang, R.; Li, Z.; Jiang, Q.; Wu, Y.; Wu, X.

10.1101/2024.03.09.584249 — bioinformatics — Posted on 2024-03-13

3126 Interpretable antibody-antigen interaction prediction by bridging structure to sequence

Liu, Y.; Nie, Z.; Chen, J.; Zheng, X.; Fu, J.; Liu, Z.; Liu, X.; Xu, F.; Huang, X.; Zhang, W.-B.; Ma, S.; Gao, W.; Tian, Y.

10.1101/2024.03.09.584264 — bioinformatics — Posted on 2024-03-13

3127 OmeSim: a genetics-based nonlinear simulator for in-between-ome and phenotype

Long, Z.; Zhang, Q.

10.1101/2024.03.10.584320 — bioinformatics — Posted on 2024-03-13

3128 A systematic exploration of unexploited genes for oxidative stress in Parkinson's disease

Suzuki, T.; Bono, H.

10.1101/2024.03.11.583425 — bioinformatics — Posted on 2024-03-13

3129 Transcriptome analysis reveals a novel DNA element that may interact with chromatin-associated proteins in Plasmodium berghei during erythrocytic development

Okafor, A.; Adam, Y.; Brors, B.; Adebiyi, E.

10.1101/2024.03.10.584310 — bioinformatics — Posted on 2024-03-13

3130 Local FK506 delivery induces osteogenesis in in vivo rat bone defect and rabbit spine fusion models

Harrer, J. A.; Fulton, T. M.; Sangadala, S.; Kaiser, J.; Devereaux, E. J.; Oliver, C.; Presciutti, S. M.; Boden, S. D.; Willett, N. J.

10.1101/2024.03.08.584163 — bioengineering — Posted on 2024-03-13

3131 Nonlinear Elastic Bottlebrush Polymer Hydrogels Modulate Actomyosin Mediated Protrusion Formation in Mesenchymal Stromal Cells

Ohnsorg, M. L.; Mash, K. M.; Khang, A.; Rao, V. V.; Kirkpatrick, B. E.; Bera, K.; Anseth, K. S.

10.1101/2024.03.08.584195 — bioengineering — Posted on 2024-03-13

3132 Transcriptional bursting, gene activation, and roles of SAGA and Mediator Tail measured using nucleotide recoding single cell RNA-seq

Schofield, J. A.; Hahn, S.

10.1101/2024.03.08.584165 — genomics — Posted on 2024-03-13

3133 Unravelling the Transcriptomic Symphony of Sarcopenia: Key Pathways and Hub Genes Altered by Muscle Ageing and Caloric Restriction Revealed by RNA Sequencing

Altab, G.; Merry, B. J.; Beckett, C. W.; Raina, P.; Lopes, I.; Goljanek-Whysall, K.; de Magalhaes, J. P.

10.1101/2024.03.09.584213 — genomics — Posted on 2024-03-13

3134 Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer's Disease fly models

Park, Y.-J.; Lu, T.-C.; Jackson, T.; Goodman, L. D.; Ran, L.; Chen, J.; Liang, C.-Y.; Harrison, E.; Ko, C.; Hsu, A.-L.; Yamamoto, S.; Qi, Y.; Bellen, H. J.; Li, H.

10.1101/2024.03.10.584317 — genetics — Posted on 2024-03-13

3135 Symmetry breaking and fate divergence during lateral inhibition in Drosophila

phan, m.-s.; Kim, J.-m.; picciotto, c.; couturier, l.; veits, n.; Mazouni, K.; schweisguth, f.

10.1101/2024.03.11.583933 — developmental biology — Posted on 2024-03-13

3136 Rejuvenation of aged oocyte through exposure to young follicular microenvironment

Wang, H.; Huang, Z.; Lee, Y.; Song, X.; Shen, X.; Shu, C.; Wu, L. H.; Pakkiri, L. S.; Lim, P. L.; Zhang, X.; Drum, C. L.; Zhu, J.; Li, R.

10.1101/2024.03.11.584343 — developmental biology — Posted on 2024-03-13

3137 Requirement of a Wnt5A-Microbiota Axis in the Maintenance of Gut B Cell Repertoire and Protection from Infection

Sengupta, S.; Sen, M.

10.1101/2024.03.08.584124 — immunology — Posted on 2024-03-13

3138 Distinct tissue-dependent composition and gene expression of human fetal innate lymphoid cells

Rodahl, I. E.; Ivarsson, M. A.; Loh, L.; Mold, J. E.; Westgren, M.; Friberg, D.; Mjosberg, J.; Bjorkstrom, N. K.; Marquardt, N.; Nixon, D. F.; Michaelsson, J.

10.1101/2024.03.12.583977 — immunology — Posted on 2024-03-13

3139 An Amygdalar Oscillator Coordinates Cellular and Behavioral Rhythms

Liu, Q.; Xiong, J.; Kim, D. W.; Lee, S. S.; Bell, B. J.; Alexandre, C.; Blackshaw, S.; Latremoliere, A.; Wu, M. N.

10.1101/2024.03.08.584151 — neuroscience — Posted on 2024-03-13

3140 Cerebral perfusion metrics calculated directly, model-free, from a hypoxia-induced step change in deoxyhemoglobin

Duffin, J.; Sayin, E. S.; Sobczyk, O.; Poublanc, J.; Mikulis, D. J.; Fisher, J. A.

10.1101/2024.03.08.584122 — neuroscience — Posted on 2024-03-13

3141 CXCL8 secreted by immature granulocytes inhibits wildtype hematopoiesis in chronic myelomonocytic leukemia

Deschamps, P.; Wacheux, M.; Gosseye, A.; Morabito, M.; Pages, A.; Lyne, A.-M.; Alfaro, A.; Rameau, P.; Imanci, A.; Chelbi, R.; Marchand, V.; Renneville, A.; Patnaik, M. M.; Lapierre, V.; Badaoui, B.; Wagner-ballon, O.; Berthon, C.; Braun, T.; Willekens, C.; Itzykson, R.; Fenaux, P.; Thepot, S.; Etienne, G.; Porteu, f.; elvira-matelot, e. M.; Droin, N.; Perie, L.; Laplane, L.; Solary, E.; Selimoglu-Buet, D.

10.1101/2024.03.08.583935 — cancer biology — Posted on 2024-03-13

3142 Sex Hormones Alter Pseudomonas aeruginosa Iron Acquisition and Virulence Factors

Ebrahim, H.; Bryan, N.; Collette, A.; Armstrong, S.; Bronowski, C.; Floyd, R.; Fothergill, J.

10.1101/2024.03.12.584604 — microbiology — Posted on 2024-03-13

3143 Spacer acquisition in type VI CRISPR-Cas systems associated with reverse transcriptase-Cas1 fusion proteins

Molina-Sanchez, M. D.; Martinez-Abarca, F.; Millan, V.; Mestre, M. R.; Toro, N.

10.1101/2024.03.12.584598 — microbiology — Posted on 2024-03-13

3144 IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.

Szabo, G.; Joshi, R.; Brezani, V.; Mey, G. M.; Guixe-Muntet, S.; Ortega-Ribera, M.; Zhuang, Y.; Zivny, A.; Werneburg, S.; Gracia-Sancho, J.

10.1101/2024.03.08.582968 — neuroscience — Posted on 2024-03-13

3145 Border-zone cardiomyocytes and macrophages contribute to remodeling of the extracellular matrix to promote cardiomyocyte invasion during zebrafish cardiac regeneration

Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R.; Beisaw, A.

10.1101/2024.03.12.584570 — cell biology — Posted on 2024-03-13

3146 Phosphoproteomic analysis reveals the diversity of signaling behind ErbB inhibitor-induced phenotypes

Vaparanta, K. M.; Jokilammi, A.; Merilahti, J.; Orling, J.; Virtanen, N.; Sahlgren, C.; Elenius, K.; Paatero, I.

10.1101/2024.03.12.584564 — cell biology — Posted on 2024-03-13

3147 The occurrence of Aerococcus urinaeequi and non-aureus Staphylococci in raw milk negatively correlates with Escherichia coli clinical mastitis

Jung, D.; Park, S.; Kurban, D.; Dufour, S.; Ronholm, J.

10.1101/2024.03.12.584643 — microbiology — Posted on 2024-03-13

3148 Sensorimotor mechanisms selective to numerosity derived from individual differences

Anobile, G.; Petrizzo, I.; Paiardini, D.; Burr, D.; Cicchini, G. M.

10.1101/2023.10.04.560837 — neuroscience — Posted on 2024-03-13

3149 A randomized, controlled, two-center preclinical trial assessing the efficacy of a new benzodiazepine-dihydropyridine hybrid molecule (JM-20) in rodent models of ischemic stroke

Ramirez-Sanchez, J.; Rex, A.; McCann, S.; Schulze, D.; Wong-Guerra, M.; Fonseca-Fonseca, L. A.; Garcia-Alfonso, E.; Ramirez-Abreu, A.; Limonta, R.; Dopatka, M.; Mosch, L.; Nunez-Figueredo, Y.; Dirnagl, U.

10.1101/2024.03.08.584085 — pharmacology and toxicology — Posted on 2024-03-13

3150 From lichens to crops: Pathogenic potential of Pseudomonas syringae from Peltigera lichens is similar to world-wide epidemic strains

Ramirez Carrera, N.; Caullireau, E.; Sigurbjornsdottir, M. A.; Vandelle, E.; Vilhelmsson, O.; Morris, C. E.

10.1101/2023.11.30.569175 — microbiology — Posted on 2024-03-13

3151 Phage predation, disease severity and pathogen genetic diversity in cholera patients

Madi, N.; Cato, E. T.; Sayeed, M. A.; Creasy-Marrazzo, A.; Cuenod, A.; Islam, K.; Khabir, M. I. U.; Bhuiyan, M. T. R.; Begum, Y.; Freeman, E.; Vustepalli, A.; Brinkley, L.; Kamat, M.; Bailey, L. S.; Basso, K. B.; Qadri, F.; Khan, A. I.; Shapiro, B. J.; Nelson, E. J.

10.1101/2023.06.14.544933 — microbiology — Posted on 2024-03-13

3152 Function of C. elegans neurons from synaptic connectivity

Emmons, S. W.

10.1101/2024.03.08.584145 — neuroscience — Posted on 2024-03-13

3153 A high resolution model of the grapevine leaf morphospace predicts synthetic leaves

Chitwood, D. H.; Torres-Lomas, E.; Hadi, E. S.; Peterson, W. L. G.; Fischer, M. F.; Rogers, S. E.; He, C.; Acierno, M. G. F.; Azumaya, S.; Benjamin, S. W.; Chalise, D. P.; Chess, E. E.; Engelsma, A. J.; Fu, Q.; Jaikham, J.; Knight, B. M.; Kodjak, N. S.; Lengyel, A.; Munoz, B. L.; Patterson, J. T.; Rincon, S. I.; Schumann, F. L.; Shi, Y.; Smith, C. C.; St. Clair, M. K.; Sweeney, C. S.; Whitaker, P.; Wu, J.; Diaz-Garcia, L.

10.1101/2024.03.08.584086 — plant biology — Posted on 2024-03-13

3154 Human-in-the-loop approach to identify functionally important residues of proteins from literature

Vollmar, M.; Tirunagari, S.; Harrus, D.; Armstrong, D.; Gaborova, R.; Gupta, D.; Afonso, M. Q. L.; Evans, G. L.; Velankar, S.

10.1101/2024.03.09.583700 — bioinformatics — Posted on 2024-03-13

3155 Uncovering the translatome impact of transcriptome induced diversity in eukaryotes: framework and innovative insights

Verma, P.; Thakur, D.; Pandit, S. B.

10.1101/2024.03.08.584087 — bioinformatics — Posted on 2024-03-13

3156 Estimating evolutionary and demographic parameters via ARG-derived IBD

Huang, Z.; Chan, Y.-b.; Balding, D.; Kelleher, J.

10.1101/2024.03.07.583855 — genetics — Posted on 2024-03-13

3157 Adaptation to complex environments reveals pervasive trade-offs and genomic targets with large pleiotropic effects

Rego, A.; Stajic, D.; Bautista, C.; Rouot, S.; Celorio-Mancera, M. d. l. P.; Stelkens, R.

10.1101/2024.01.24.577006 — evolutionary biology — Posted on 2024-03-13

3158 In sickness and in health: RNA-Seq finds viruses associated with mutualist quality in the Amazonian plant-ant Allomerus octoarticulatus

Tocora, M. C.; Reid, C.; Huisken, J.; Xue, H.; Frederickson, M. E.

10.1101/2024.03.12.583798 — ecology — Posted on 2024-03-13

3159 callsync: an R package for alignment and analysis of multi-microphone animal recordings

Smeele, S. Q.; Tyndel, S. A.; Klump, B. C.; Alarcon-Nieto, G.; Aplin, L. M.

10.1101/2023.02.07.527470 — ecology — Posted on 2024-03-13

3160 An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration

Marefati, M.; Fernandez-Vallone, V.; Leprovots, M.; Vasile, G.; Libert, F.; Lefort, A.; Dinsart, G.; Weber, A.; Jetzer, J.; Garcia, M.-I.; Vassart, G.

10.1101/2024.03.11.584399 — developmental biology — Posted on 2024-03-13

3161 Autophagosome turnover requires Arp2/3 complex-mediated maintenance of lysosomal integrity

Theodore, C.; Wagner, L.; Campellone, K.

10.1101/2024.03.12.584718 — cell biology — Posted on 2024-03-13

3162 Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel

Huang, T.; Chen, X.; He, J.; Zheng, P.; Luo, Y.; Wu, A.; Yan, H.; Yu, B.; Chen, D.; Huang, Z.

10.1101/2023.07.18.549410 — molecular biology — Posted on 2024-03-13

3163 EasyGrid: A versatile platform for automated cryo-EM sample preparation and quality control

Gemin, O.; Armijo, V.; Hons, M.; Bissardon, C.; Linares, R.; Bowler, M. W.; Wolff, G.; Kovalev, K.; Babenko, A.; Salo, V. T.; Schneider, S.; Rossi, C.; Lecomte, L.; Deckers, T.; Lauzier, K.; Janocha, R.; Felisaz, F.; Sinoir, J.; Galej, W. P.; Mahamid, J.; Muller, C. W.; Eustermann, S.; Mattei, S.; Cipriani, F.; Papp, G.

10.1101/2024.01.18.576170 — molecular biology — Posted on 2024-03-13

3164 Emergence of Orientation Pinwheels in a Self-Evolving Spiking Neural Network: Enhancing Visual Coding Efficiency and Reliability

Zhong, H.; Wang, H.; Dai, W. P.; Huang, M.; Huang, Y.; An, M.; Roe, A. W.; Yu, Y.

10.1101/2024.03.08.583887 — neuroscience — Posted on 2024-03-13

3165 Arteriolar degeneration and stiffness in cerebral amyloid angiopathy are linked to β-amyloid deposition and lysyl oxidase.

Ventura-Antunes, L.; Nackenoff, A.; Romero-Fernandez, W.; Bosworth, A. M.; Prusky, A.; Wang, E.; Carvajal-Tapia, C.; Shostak, A.; Harmsen, H.; Mobley, B.; Maldonado, J.; Solopova, E.; Snider, J. C.; Merryman, W. D. D.; Lippmann, E.; Schrag, M.

10.1101/2024.03.08.583563 — neuroscience — Posted on 2024-03-13

3166 Not seeing the forest for the trees: Combination of path integration and landmark cues in human virtual navigation

Scherer, J.; Muller, M. M.; Unterbrink, P.; Meier, S.; Egelhaaf, M.; Bertrand, O. J. N.; Boeddeker, N.

10.1101/2023.10.25.563902 — neuroscience — Posted on 2024-03-13

3167 Human monocyte subtype expression of neuroinflammation and -regeneration-related genes is linked to age and sex

Tampe, J.; Monni, E.; Brogardh, E.; Palma-Tortosa, S.; Boiers, C.; Lindgren, A. G.; Kokaia, Z.

10.1101/2024.03.10.584323 — neuroscience — Posted on 2024-03-13

3168 Making predictions using poorly identified mathematical models

Simpson, M. J.; Maclaren, O. J.

10.1101/2023.11.26.568740 — systems biology — Posted on 2024-03-13

3169 A fungal transcription factor BOT6 facilitates the transition of a beneficial root fungus into an adapted anthracnose pathogen

Ujimatsu, R.; Takino, J.; Nakamura, M.; Haba, H.; Minami, A.; Hiruma, K.

10.1101/2024.03.10.584252 — plant biology — Posted on 2024-03-13

3170 Mechanisms of genomic instability dictate cytosolic DNA composition and dendritic cell mediated anti-tumor immunity

Mosley, S. R.; Chen, A.; Doell, D. N.; Choi, S.; Mowat, C.; Meier-Stephenson, F.; Meier-Stephenson, V.; Baker, K.

10.1101/2024.03.08.584184 — cancer biology — Posted on 2024-03-13

3171 Robust cytoplasmic partitioning by solving an intrinsic cytoskeletal instability

Rinaldin, M.; Kickuth, A.; Dalton, B.; Xu, Y.; Di Talia, S.; Brugues, J.

10.1101/2024.03.12.584684 — biophysics — Posted on 2024-03-13

3172 Transcription regulates the spatio-temporal dynamics of genes through micro-compartmentalization

Salari, H.; Fourel, G.; Jost, D.

10.1101/2023.07.18.549489 — biophysics — Posted on 2024-03-13

3173 PIGOME: An Integrated and Comprehensive Multi-omics Database for Pig Functional Genomics Studies

Han, G.; Yang, P.; Zhang, Y.; Li, Q.; Fan, X.; Chen, R.; Yan, C.; Zeng, M.; Yang, Y.; Tang, Z.

10.1101/2024.03.10.583139 — bioinformatics — Posted on 2024-03-13

3174 Transcriptomic analysis of TGFβ-mediated fibrosis in primary human Tenon's fibroblasts

Pasvanis, Z.; Boynes, A.; Kong, R. C. K.; Chan, E. C.; Wong, R. C. B.; Fan Gaskin, J. C.

10.1101/2024.03.09.583791 — bioinformatics — Posted on 2024-03-13

3175 Inferring allele-specific copy number aberrations and tumor phylogeography from spatially resolved transcriptomics

Ma, C.; Balaban, M.; Liu, J.; Chen, S.; Ding, L.; Raphael, B.

10.1101/2024.03.09.584244 — bioinformatics — Posted on 2024-03-13

3176 The conserved membrane-proximal domain of Sbh1/ Sec61β guides signal peptides into the Sec61 channel

Yadhanapudi, L.; Bhadra, P.; Barbieri, G.; Jung, M.; Lommel, M.; Helms, V.; Romisch, K.

10.1101/2024.03.12.584615 — biochemistry — Posted on 2024-03-13

3177 Chemoproteomic profiling of serine hydrolases reveals the dynamic role of lipases in Phaeodactylum tricornutum

Dolui, A. K.; Yaakov, B.; Jasinska, W.; Barak, S.; Brotman, Y.; Khozin-Goldberg, I.

10.1101/2024.03.12.582592 — biochemistry — Posted on 2024-03-13

3178 Common cuckoo female host selection is not determined by host quality but can affect cuckoo nestling growth when parasitising Common redstarts

Abaurrea, T.; Moreras, A.; Tolvanen, J.; Thomson, R. L.; Thorogood, R.

10.1101/2024.03.11.583276 — animal behavior and cognition — Posted on 2024-03-13

3179 Social ageing can protect against infectious disease in a group-living primate

Siracusa, E. R.; Pavez-Fox, M. A.; Negron-Del Valle, J. E.; Phillips, D.; Platt, M. L.; Snyder-Mackler, N.; Higham, J. P.; Brent, L. J. N.; Silk, M. J.

10.1101/2024.03.09.584237 — animal behavior and cognition — Posted on 2024-03-13

3180 Chromosome-scale genome assembly of Apocynum pictum, a drought-tolerant medicinal plant from the Tarim Basin

Xie, W.; Bai, B.; Wang, Y.

10.1101/2024.03.08.584125 — genomics — Posted on 2024-03-13

3181 Do sister species respond similarly to dry conditions? An ecophysiological approach in natura

Keilani, H. S.; Avenant, N. L.; Caminade, P.; Pillay, N.; Ganem, G.

10.1101/2024.03.11.583554 — ecology — Posted on 2024-03-13

3182 Forest and Biodiversity 2: a tree diversity experiment to understand the consequences of multiple dimensions of diversity and composition for long-term ecosystem function and resilience

Cavender-Bares, J.; Grossman, J.; Guzman Quesada, J. A.; Hobbie, S. E.; Kaproth, M.; Kothari, S.; Lapadat, C.; Montgomery, R.; Park, M.

10.1101/2024.03.09.584227 — ecology — Posted on 2024-03-13

3183 Age-specificity in territory quality and spatial structure in a wild bird population

Woodman, J. P.; Firth, J. A.; Cole, E. F.; Sheldon, B. C.

10.1101/2024.03.11.584379 — ecology — Posted on 2024-03-13

3184 Exploration of phosphoproteomic association during epimorphic regeneration

Banu, S.; V, A. P.; Mandal, K.; Idris, M. M.

10.1101/2024.03.08.584197 — developmental biology — Posted on 2024-03-13

3185 Her9 controls the stemness properties of the hindbrain boundary cells

Engel-Pizcueta, C.; Hevia, C. F.; Voltes, A.; LIVET, J.; Pujades, C.

10.1101/2024.03.12.584657 — developmental biology — Posted on 2024-03-13

3186 Cdon is required for organ Left-Right patterning via regulating DFCs migration and the sequential ciliogenesis

Deng, Z.; Chang, W.; Li, C.; Li, B.; Huang, S.; Huang, J.; Zhang, K.; Li, Y.; Liu, X.; Ran, Q.; Guo, Z.; Huang, S.

10.1101/2024.03.12.584572 — developmental biology — Posted on 2024-03-13

3187 Regenerative clustering of Enteroblasts in the Drosophila midgut revealed by a morphometric analysis

Zhu, F.; Murray, M. J.

10.1101/2024.03.10.584282 — developmental biology — Posted on 2024-03-13

3188 Activation of the mPFC-NAc pathway reduces motor impulsivity but does not affect risk-related decision-making in innately high-impulsive rats

Arrondeau, C.; Uruena-Mendez, G.; Marchessaux, F.; Goutaudier, R.; Ginovart, N.

10.1101/2024.03.08.584121 — neuroscience — Posted on 2024-03-13

3189 Cortico-striatal action control inherent of opponent cognitive-motivational styles

Avila, C.; Sarter, M.

10.1101/2024.03.12.584623 — neuroscience — Posted on 2024-03-13

3190 Choroid plexus enlargement in acute neuroinflammation is tightly interrelated to the tyrosine receptor signalling

Luessi, F.; Schiffer, J.; Gonzalez-Escamilla, G.; Fleischer, V.; Engel, S.; Ciolac, D.; Koeck, T.; Wild, P. S.; Gruchot, J.; Ruck, T.; Othmann, A.; Bittner, S.; Meuth, S. G.; Zipp, F.; Stueve, O.; Groppa, S.

10.1101/2024.03.09.583615 — neuroscience — Posted on 2024-03-13

3191 Initial Learning in the Brain: From Rules to Action

Fregni, S.; Wolfensteller, U.; Ruge, H.

10.1101/2024.03.12.584566 — neuroscience — Posted on 2024-03-13

3192 Cortical traveling waves link visual and frontal cortex during working memory-guided behavior

Luo, C.; Ester, E.

10.1101/2024.03.12.584543 — neuroscience — Posted on 2024-03-13

3193 Drumming Performance and Underlying Muscle Activities in a Professional Rock Drummer with Lower-Limb Dystonia: A Case Study

Honda, K.; Sata, S.; Komine, M.; Yamaguchi, S.; Kim, S.; Kashino, M.; Fujii, S.

10.1101/2024.03.09.584247 — neuroscience — Posted on 2024-03-13

3194 LINC complex alterations are a hallmark of sporadic and familial ALS/FTD

Sirtori, R.; Gregoire, M. J.; Potts, E.; Collins, A.; Donatelli, L.; Fallini, C.

10.1101/2024.03.08.584123 — neuroscience — Posted on 2024-03-13

3195 Phylogenetically distant enzymes localized in cytosol and plastids drive citral biosynthesis in lemongrass

Gupta, P.; Sharma, A.; Kiran, N. R.; Pranav Raj, T. K. A.; Krishna, R.; Nagegowda, D. A.

10.1101/2024.03.11.583845 — plant biology — Posted on 2024-03-13

3196 Adaptive landscapes unveil the complex evolutionary path to mammalian forelimb function and posture

Brocklehurst, R. J.; Mercado, M.; Angielczyk, K. D.; Pierce, S. E.

10.1101/2024.03.12.584484 — paleontology — Posted on 2024-03-13

3197 Explainable deep learning on 7500 whole genomes elucidates cancer-specific patterns of chromosomal instability

al-Badri, M. A.; Cross, W. C.; Barnes, C. P.

10.1101/2024.03.08.584160 — cancer biology — Posted on 2024-03-13

3198 Beyond blooms: A novel time series analysis framework predicts seasonal keystone species and sheds light on ecosystem stability in the Fram strait

Oldenburg, E.; Kronberg, R. M.; Metfies, K.; von Appen, W.-J.; Wietz, M.; Bienhold, C.; Popa, O.; Ebenhoeh, O. M.

10.1101/2024.03.11.583746 — bioinformatics — Posted on 2024-03-13

3199 Male reproductive phenotype and coercive mating performance in the guppy Poecilia reticulata

Glavaschi, A.; Morbiato, E.; Pilastro, A.

10.1101/2024.03.10.584275 — animal behavior and cognition — Posted on 2024-03-13

3200 Differential selective regimes identify categories of transposable elements with regulatory function

Cerruti, Y.; Fusco, D.; Jahanbin, M.; Marnetto, D.; Provero, P.

10.1101/2024.03.11.584453 — genetics — Posted on 2024-03-13

3201 Independent expansion, selection and hypervariability of the TBC1D3 gene family in humans

Eichler, E.; Guitart, X.; Porubsky, D.; Yoo, D.; Dougherty, M. L.; Dishuck, P. C.; Munson, K. M.; Lewis, A. P.; Hoekzema, K.; Knuth, J.; Chang, S.; Pastinen, T.

10.1101/2024.03.12.584650 — genetics — Posted on 2024-03-13

3202 Islands promote diversification within the silvereye clade: a phylogenomic analysis of a great speciator

Estandia, A.; Recalde, N. M.; Sendell-Price, A. T.; Potvin, D. A.; Robertson, B. C.; Clegg, S. M.

10.1101/2024.03.11.584438 — evolutionary biology — Posted on 2024-03-13

3203 Environmental similarity between relatives reduces heritability of reproductive timing in wild great tits

Jones, C. V.; Regan, C. E.; Cole, E. F.; Firth, J. A.; Sheldon, B. C.

10.1101/2024.03.11.584392 — evolutionary biology — Posted on 2024-03-13

3204 Single-character insertion-deletion model preserves long indels in ancestral sequence reconstruction

Jowkar, G.; Pecerska, J.; Gil, M.; Anisimova, M.

10.1101/2024.03.09.584071 — evolutionary biology — Posted on 2024-03-13

3205 Functional genetics reveals modulators of anti-microtubule drug sensitivity

Su, K.-C.; Radul, E.; Maier, N. K.; Tsang, M.-J.; Goul, C. S.; Moodie, B.; Keys, H. R.; Cheeseman, I. M.

10.1101/2024.03.12.584469 — cell biology — Posted on 2024-03-13

3206 Mesenchymal stromal cell chondrogenesis under ALK1/2/3-specific BMP inhibition: A revision of the prohypertrophic signalling network concept

Diederichs, S.; Dreher, S. I.; Nueesch, S.-A.; Schmidt, S.; Merle, C.; Richter, W.

10.1101/2024.03.12.584629 — cell biology — Posted on 2024-03-13

3207 Katanin, kinesin-13 and ataxin-2 inhibit premature interaction between maternal and paternal genomes in C. elegans zygotes

Beath, E. A.; Bailey, C.; Magadam, M. M.; Qiu, S.; McNally, K. P. L.; McNally, F. J.

10.1101/2024.03.12.584242 — cell biology — Posted on 2024-03-13

3208 Perceptual clustering in auditory streaming

Larigaldie, N.; Yates, T.; Beierholm, U. R.

10.1101/2021.05.27.446050 — neuroscience — Posted on 2024-03-12

3209 Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells

Wang, J.-P.; Hung, C.-H.; Liou, Y.-H.; Liu, C.-C.; Yeh, K.-H.; Wang, K.-Y.; Lai, Z.-S.; Chatterjee, B.; Hsu, T.-C.; Lee, T.-L.; Shyu, Y.-C.; Hsiao, P.-W.; Chen, L.-Y.; Chuang, T.-J.; Yu, C.-H. A.; Liao, N.-S.; Shen, C.-K. J.

10.1101/2023.04.21.537849 — cancer biology — Posted on 2024-03-12

3210 A Boltzmann model predicts glycan structures from lectin binding

Yom, A.; CHIANG, W.-T.; Lewis, N.

10.1101/2023.06.03.543532 — bioinformatics — Posted on 2024-03-12

3211 Genomic context sensitizes regulatory elements to genetic disruption

Ordonez, R.; Zhang, W.; Ellis, G.; Zhu, Y.; Ashe, H. J.; Ribeiro-dos-Santos, A. M.; Brosh, R.; Huang, E.; Hogan, M. S.; Boeke, J. D.; Maurano, M. T.

10.1101/2023.07.02.547201 — genomics — Posted on 2024-03-12

3212 An octopamine-specific GRAB sensor reveals a monoamine relay circuitry that boosts aversive learning

Lv, M.; Cai, R.; Zhang, R.; Xia, X.; Li, X.; Wang, Y.; Wang, H.; Zeng, J.; Xue, Y.; Mao, L.; Li, Y.

10.1101/2024.03.09.584200 — neuroscience — Posted on 2024-03-12

3213 STN-PFC circuit related to attentional fluctuations during non-movement decision-making

Ai, S.

10.1101/2023.12.10.571030 — neuroscience — Posted on 2024-03-12

3214 Defense-related callose synthase PMR4 promotes root hair callose deposition and adaptation to phosphate deficiency in Arabidopsis thaliana

Okada, K.; Yachi, K.; Nguyen, T. A. N.; Kanno, S.; Yasuda, S.; Tadai, H.; Tateda, C.; Lee, T.-H.; Nguyen, U.; Inoue, K.; Miyashima, S.; Hiruma, K.; Miwa, K.; Maekawa, T.; Notaguchi, M.; Saijo, Y.

10.1101/2023.07.05.547890 — plant biology — Posted on 2024-03-12

3215 3D culture of pancreatic cancer cells in vitro recapitulates an aberrant mitochondrial oxidative phosphorylation genotype observed in vivo

Treherne, J. M.; Kus, K.; Krzykawski, M. P.; Earnshaw, D. L.; Krzykawska, R.; Biesaga, B.; Statkiewicz, M.; Unrug-Bielawska, K.; Sandowska-Markiewicz, Z.; Mikula, M.; Alfaro, J. A.

10.1101/2024.03.08.583569 — cancer biology — Posted on 2024-03-12

3216 A genome-wide association study implicates the olfactory system in Drosophila melanogaster diapause-associated lifespan extension and fecundity

Easwaran, S.; Montell, D.

10.1101/2024.03.10.584341 — genetics — Posted on 2024-03-12

3217 Sex-specific viability effects of mutations in Drosophila melanogaster

Melde, R. H.; Abraham, J. M.; Ugolini, M. R.; Castle, M. P.; Fjalstad, M. M.; Blumstein, D. M.; Sharp, N. P.

10.1101/2024.03.09.584240 — evolutionary biology — Posted on 2024-03-12

3218 Evolutionary integration of the geography and pacing of the annual cycle in migratory birds

Winger, B. M.; La Sorte, F. A.; Hack, M. D.; Pegan, T. M.

10.1101/2024.03.08.584102 — ecology — Posted on 2024-03-12

3219 Interspecific trait differences drive plant community responses on serpentine soils.

Delhaye, G.; Dimitrakopoulos, P. G.; Adamidis, G. C.

10.1101/2024.03.08.584143 — ecology — Posted on 2024-03-12

3220 Key link between iron and the size structure of three main mesoplanktonic groups (Crustaceans, Rhizarians, and colonial N2-fixers) in the Global Ocean.

Dugenne, M.; Corrales-Ugalde, M.; Luo, J.; Stemmann, L.; Irisson, J.-O.; Lombard, F.; O'Brien, T.; Stock, C.; Kiko, R.

10.1101/2024.03.08.584097 — ecology — Posted on 2024-03-12

3221 Cell 3D Positioning by Optical encoding (C3PO) and its application to spatial transcriptomics

Cotterell, J.; Swoger, J.; Robert-Moreno, A.; Blaya, H. C.; Musy, M.; Sharpe, J.

10.1101/2024.03.12.584578 — molecular biology — Posted on 2024-03-12

3222 Resolved Genomes of Wastewater ESBL-Producing Escherichia coli and Metagenomic Analysis of Source Wastewater Samples

Cheney, C.; Johnson, J.; Ste.Marie, J. P.; Gacosta, K. Y. M.; Denlinger Drumm, N. B.; Jones, G.; Waite-Cusic, J.; Navab-Daneshmand, T.

10.1101/2024.03.12.584675 — microbiology — Posted on 2024-03-12

3223 Long-term evolution reveals the role of the circadian cycle in the environmental adaptation of cyanobacteria

Mendana, A.; Santos-Merino, M.; Gutierrez-Lanza, R.; Dominguez-Quintero, M.; Medina, J. M.; Gonzalez-Guerra, A.; Campa, V.; Ducos-Galand, M.; Lopez-Igual, R.; Volke, D. C.; Gugger, M.; Nikel, P. I.; Mazel, D.; de la Cruz, F.; Fernandez-Lopez, R.

10.1101/2024.03.12.584591 — microbiology — Posted on 2024-03-12

3224 Hematopoietic stem cell gene therapy improves outcomes in a clinically relevant mousemodel of Multiple Sulfatase Deficiency

Pham, V.; Tricoli, L.; Hong, X.; Wongkittichote, P.; Castruccio Castracani, C.; Guerra, A.; Schlotawa, L.; Adang, L. A.; Kuhs, A.; Cassidy, M. M.; Kane, O.; Tsai, E.; Presa, M.; Lutz, C. M.; Rivella, S. B.; Ahrens-Nicklas, R. C.

10.1101/2024.03.08.584099 — neuroscience — Posted on 2024-03-12

3225 miRNA circuit modules for precise, tunable control of gene expression

Du, R.; Flynn, M. J.; Honsa, M.; Jungmann, R.; Elowitz, M. B.

10.1101/2024.03.12.583048 — synthetic biology — Posted on 2024-03-12

3226 Small molecule and cell contact-inducible systems for controlling expression and differentiation in stem cells

Soliman, S. S.; Shah, D. H.; El-Samad, H.; Weinberg, Z. Y.

10.1101/2024.03.12.584464 — synthetic biology — Posted on 2024-03-12

3227 Australian researchers' perceptions and experiences with stem cell registration.

Hu, M.; Santos, D.; Lopes, E.; Nicol, D.; Kurtz, A.; Mah, N.; Muller, S. C.; Ankeny, R. A.; Wells, C.

10.1101/2024.03.11.584334 — scientific communication and education — Posted on 2024-03-12

3228 WITHDRAWN: Understanding Regeneration: investigating the apical notch and meristem re-emergence in Marchantia polymorpha

Marron, A. O.; Rebmann, M.; Delmans, M.; Haseloff, J. O.

10.1101/2024.02.04.575544 — plant biology — Posted on 2024-03-12

3229 Mutational Profiling of SARS-CoV-2 PLpro in human cells reveals requirements for function, structure, and drug escape

Wu, X.; Go, M.; Nguyen, J. V.; Kuchel, N. W.; Lu, B. G. C.; Lowes, K. N.; Calleja, D. J.; Mitchell, J. P.; Lessene, G.; Komander, D.; Call, M. E.; Call, M. J.

10.1101/2024.03.11.584210 — biochemistry — Posted on 2024-03-12

3230 Analysis of meiotic recombination in Drosophila simulans shows heterozygous inversions do not cause an interchromosomal effect

Man, B.; Kim, E.; Vadlakonda, A.; Stern, D. L.; Crown, N.

10.1101/2024.03.09.584235 — genetics — Posted on 2024-03-12

3231 Why models underestimate tropical forest productivity: a case study in West Africa

zhang-zheng, h.; Deng, X.; Stocker, B.; Ruijie, R.; Thomson, E.; Adu-Bredu, S.; Duah-Gyamfi, A.; Gvozdevaite, A.; Moore, S.; Oliveras Menor, I.; Prentice, I. C.; Malhi, Y.

10.1101/2024.03.08.584066 — ecology — Posted on 2024-03-12

3232 N-glycosylated molecules act as a co-precipitant in RNA purification

Kim, S.; Choi, Y.-g.; Janssen, K.; Bull, C.; Joshi, B. S.; Pomorski, A.; Raz, V.; Tanenbaum, M. E.; Miesen, P.; Li, Z.; Joo, C.

10.1101/2024.03.12.584655 — molecular biology — Posted on 2024-03-12

3233 The histone chaperone CAF-1 maintains the stability of the ribosomal RNA gene cluster by suppressing end resection of replication-associated DNA double-strand breaks.

Sasaki, M.; Kobayashi, T.; Futami, H.

10.1101/2024.03.12.584701 — molecular biology — Posted on 2024-03-12

3234 Ribosomes modulate transcriptome abundance via generalized frameshift and out-of-frame mRNA decay.

Zhang, Y.; Nersisyan, L.; Fuerst, E.; Alexopoulos, I.; Huch, S.; Bassot, C.; Garre, E.; Sunnerhagen, P.; Piazza, I.; Pelechano, V.

10.1101/2024.03.12.584696 — molecular biology — Posted on 2024-03-12

3235 Cooperative colonization of the host and pathogen dissemination involves stochastic and spatially structured expression of virulence traits

Lopez-Pagan, N.; Rufian, J. S.; Luneau, J.; Sanchez-Romero, M.-A.; Aussel, L.; van Vliet, S.; Ruiz-Albert, J.; Beuzon, C. R.

10.1101/2024.03.12.584633 — microbiology — Posted on 2024-03-12

3236 Root exudation and rhizosphere microbial recruitment are influenced by novel plant trait diversity in carrot genotypes

Anderson, H. M.; Cagle, G. A.; Majumder, E. L.- W.; Silva, E.; Dawson, J.; Simon, P.; Freedman, Z.

10.1101/2024.03.12.583384 — microbiology — Posted on 2024-03-12

3237 The molecules lost NEW COMPOUNDS BINDING AT THE HISTAMINE SITE OF THE NMDA RECEPTOR (NMDA(HA)R)

Armand, V.

10.1101/2024.03.08.583891 — neuroscience — Posted on 2024-03-12

3238 Hemozoin induces Malaria via activation of DNA damage, p38 MAPK and Neurodegenerative Pathways in Human iPSC-derived Neuronal Model of Cerebral Malaria

Pranty, A. I.; Szepanowski, L.-P.; wruck, W.; Karikari, A. A.; Adjaye, J.

10.1101/2024.03.08.584068 — neuroscience — Posted on 2024-03-12

3239 GABAergic amacrine cells balance biased chromatic information in the mouse retina

Korympidou, M. M.; Strauss, S.; Schubert, T.; Franke, K.; Berens, P.; Euler, T.; Vlasits, A.

10.1101/2024.03.08.584060 — neuroscience — Posted on 2024-03-12

3240 Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics

Dessalles, C. A.; Cuny, N.; Boutillon, A.; Salipante, P. F.; Babataheri, A.; Barakat, A. I.; Salbreux, G.

10.1101/2024.03.10.584287 — biophysics — Posted on 2024-03-12

3241 HyperTraPS-CT: Inference and prediction for accumulation pathways with flexible data and model structures

Aga, O. N. L.; Brun, M.; Giannakis, K.; Dauda, K. A.; Diaz-Uriarte, R.; Johnston, I.

10.1101/2024.03.07.583841 — bioinformatics — Posted on 2024-03-12

3242 Predicting nanocarrier permeation across the human intestine in vitro: Model matters

Jung, N.; Schreiner, J.; Baur, F.; Vogel-Kindgen, S.; Windbergs, M.

10.1101/2024.03.08.584089 — pharmacology and toxicology — Posted on 2024-03-12

3243 Integrated in vivo functional screens and multi-omics analyses identify alpha-2,3-sialylation as essential for melanoma maintenance

Agrawal, P.; Chen, S.; de Pablos, A.; Jame-Chenarboo, F.; Miera Saenz de Vega, E.; Darvishian, F.; Osman, I.; Lujambio, A.; Mahal, L. K.; Hernando, E.

10.1101/2024.03.08.584072 — cancer biology — Posted on 2024-03-12

3244 GFPrint™: A MACHINE LEARNING TOOL FOR TRANSFORMING GENETIC DATA INTO CLINICAL INSIGHTS

Sanz-Martin, G.; Migliore, D. P.; Gomez del Campo, P.; del Castillo-Izquierdo, J.; Dominguez, J. M.

10.1101/2024.03.08.584090 — bioinformatics — Posted on 2024-03-12

3245 GATLncLoc+C&S: Prediction of LncRNA subcellular localization based on corrective graph attention network

Deng, X.; Tang, L.; Liu, L.

10.1101/2024.03.08.584063 — bioinformatics — Posted on 2024-03-12

3246 Transcranial Functional Ultrasound Imaging Detects Focused Ultrasound Neuromodulation Induced Hemodynamic Changes in Mouse and Nonhuman Primate Brains In Vivo

Christian, A.; Bendig, J.; Blackman, S. G.; McCune, E. P.; Bae, S.; Jimenez-Gambin, S.; Ji, R.; Konofagou, E. E.

10.1101/2024.03.08.583971 — bioengineering — Posted on 2024-03-12

3247 A genetic perspective on the recent demographic history of Ireland and Britain

Shanmugam, A.; Merrigan, M.; O'Reilly, S.; Molloy, A. M.; Brody, L.; Hardiman, O.; McLaughlin, R. L.; Cavalleri, G. L.; Byrne, R. P.; Gilbert, E. H.

10.1101/2024.03.08.584042 — genetics — Posted on 2024-03-12

3248 Chitosan-coated carboxylic acids show antimicrobial activity against antibiotic-resistant Gram-negative and positive pathogens

Cogan, T.; James-Meyer, L.

10.1101/2022.09.02.506354 — microbiology — Posted on 2024-03-12

3249 Chloride intracellular channel 4 (CLIC4) is a global regulator of type 1 interferon signaling in Systemic Sclerosis (SSc) epithelial cells

Wasson, C. W.; Dibb, S. L.; Caballero Ruiz, B.; Clavane, E. M.; Wells, R.; Kakkar, V.; De Lorenzis, E.; Ross, R. L.; Bryon, J.; Derrett-Smith, E.; Denton, C. P.; Meakin, P. J.; Del Galdo, F.

10.1101/2024.03.08.583925 — immunology — Posted on 2024-03-12

3250 Using behavioral biomarkers to redefine epochs of spontaneous recovery following spinal cord injury

Eisdorfer, J. T.; Thackray, J. K.; Theis, T.; Vivinetto, A.; Ricci, M. T.; Lin, S.; Oputa, O.; Martinez, A. M.; Nacht, H. D.; Tschang, M.; Mahmood, M.; Tucker, A.; Bohic, M.; Pusuloori, S.; Zmoyro, L.; Kumar, S.; Abraira Lab Computational Group, ; Schachner, M.; Popovich, P.; Ferguson, A. R.; McTigue, D.; Tysseling, V. M.; Dulin, J.; Hollis, E.; Datta, S. R.; Abraira, V. E. G.

10.1101/2023.10.31.564826 — neuroscience — Posted on 2024-03-12

3251 Chronic Ethanol Exposure Produces Persistent Impairment in Cognitive Flexibility and Decision Signals in the Striatum

Cheng, Y.; Magnard, R.; Langdon, A.; Lee, D.; Janak, P. H.

10.1101/2024.03.10.584332 — neuroscience — Posted on 2024-03-12

3252 Spatial Lipidomics Maps Brain Alterations Associated with Mild Traumatic Brain Injury

Leontyev, D.; Pulliam, A. N.; Ma, X.; Gaul, D. A.; LaPlaca, M. C.; Fernandez, F. M.

10.1101/2024.01.25.577203 — neuroscience — Posted on 2024-03-12

3253 Dynamin-2 Mutations Linked to Neonatal-onset Centronuclear Myopathy impair exocytosis and endocytosis in adrenal chromaffin cells.

Bayones, L.; Guerra-Fernandez, M. J.; Figuroa-Cares, C.; Gallo, L. I.; Alfonso-Bueno, S.; Baez-Matus, X.; Gonzalez-Jamett, A.; Cardenas, A. M.; Marengo, F. D.

10.1101/2024.03.07.583689 — neuroscience — Posted on 2024-03-12

3254 Preserved spontaneous mentalizing amid reduced intersubject variability in autism during a movie narrative

Mangnus, M.; Koch, S. B. J.; Cai, K.; Greidanus Romaneli, M.; Hagoort, P.; Basnakova, J.; Stolk, A.

10.1101/2024.03.08.583911 — neuroscience — Posted on 2024-03-12

3255 Circadian dynamics of the Zbtb14 protein in the ventral hippocampus are disrupted in epileptic mice

Guntan, I.; Ghestem, A.; Nazaruk, K.; Nizinska, K.; Olszewski, M.; Nowicka, D.; Bernard, C.; Lukasiuk, K.

10.1101/2024.03.07.583828 — neuroscience — Posted on 2024-03-12

3256 Construction, analysis and assessment of relevance of an algebraic model for a class of biochemical networks

KUNDU, S.

10.1101/2024.03.07.583960 — systems biology — Posted on 2024-03-12

3257 ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF

Magnitov, M. D.; Maresca, M.; Alonso Saiz, N.; Teunissen, H.; Braccioli, L.; de Wit, E.

10.1101/2024.03.08.583864 — systems biology — Posted on 2024-03-12

3258 Chemotherapy-driven de novo Wnt pathway activation dictates a dynamic shift to a drug-tolerant state in breast cancer cells

Lluis, F.; Ellaithy, Y.; Abreu de Oliveira, W. A.; Pabba, A.; Qualizza, A.; Richard, F.; Athanasouli, P.; Luci, C. R.; De Wispelaere, W.; Mourao, L.; Hamer, S.; Moens, S.; De Jaime-Soguero, A.; Francesca Baietti, M.; Hutten, S. J.; Jonkers, J.; Sammut, S.-J.; Soenen, S. J.; Scheele, C. L.; Bruna, A.; Desmedt, C.; Annibali, D.

10.1101/2024.03.08.584051 — cancer biology — Posted on 2024-03-12

3259 Three-dimensional spatio-angular fluorescence microscopy with a polarized dual-view inverted selective-plane illumination microscope (pol-diSPIM)

Chandler, T.; Guo, M.; Su, Y.; Chen, J.; Wu, Y.; Liu, J.; Agashe, A.; Fischer, R. S.; Mehta, S. B.; Kumar, A.; Baskin, T. I.; Jamouille, V.; Liu, H.; Swaminathan, V.; Nain, A.; Oldenbourg, R.; La Riviere, P.; Shroff, H.

10.1101/2024.03.09.584243 — biophysics — Posted on 2024-03-12

3260 A proteome-wide quantitative platform for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs

Brown, C.; Ghosh, S.; McAllister, R.; Kumar, M.; Walker, G.; Sun, E.; Aman, T.; Panda, A.; Kumar, S.; Li, W. V.; Coleman, J.; Liu, Y.; Rothman, J. E.; Bhattacharyya, M.; Gupta, K.

10.1101/2024.02.10.579775 — biophysics — Posted on 2024-03-12

3261 Globally distributed bacteriophage genomes reveal mechanisms of tripartite phage-bacteria-coral interactions

Wallace, B. A.; Varona, N. S.; Hesketh-Best, P.; Silveira, C.

10.1101/2024.03.11.584349 — genomics — Posted on 2024-03-12

3262 Causal inference with observational data and unobserved confounding variables

Byrnes, J. E. K.; Dee, L. E.

10.1101/2024.02.26.582072 — ecology — Posted on 2024-03-12

3263 Escape from X inactivation is directly modulated by levels of Xist non-coding RNA

Hauth, A.; Panten, J.; Kneuss, E.; Picard, C.; Servant, N.; Rall, I.; Perez-Rico, Y. A.; Clerquin, L.; Servaas, N.; Villacorta, L.; Jung, F.; Luong, C.; Chang, H. Y.; Zaugg, J. B.; Stegle, O.; Odom, D. T.; Loda, A.; heard, E.

10.1101/2024.02.22.581559 — developmental biology — Posted on 2024-03-12

3264 Intestinal barrier function in the naked mole-rat: an emergent model for gastrointestinal insights

Aguilera-Lizarraga, J.; Ritoux, A.; Bulmer, D.; Smith, E. S. J.

10.1101/2024.01.17.576063 — physiology — Posted on 2024-03-12

3265 Interpreting single-cell messages in normal and aberrant hematopoiesis with the Cell Marker Accordion

Busarello, E.; Biancon, G.; Lauria, F.; Ibnat, Z.; Ramirez, C.; Tome, G.; Aass, K. R.; VanOudenhove, J. J.; Standal, T.; Viero, G.; Halene, S.; Tebaldi, T.

10.1101/2024.03.08.584053 — bioinformatics — Posted on 2024-03-12

3266 PGBTR: A powerful and general method for inferring bacterial transcriptional regulatory networks

Gu, W.-C.; Ma, B.-G.

10.1101/2024.03.08.584073 — bioinformatics — Posted on 2024-03-12

3267 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping

Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.

10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-12

3268 SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition

Zhang, Q. E.; Lindenberger, J.; Parsons, R.; Thakur, B.; Parks, R.; Park, C. S.; Huang, X.; Sammour, S.; Janowska, K.; Spence, T. N.; Edwards, R. J.; Martin, M.; Williams, W. B.; Gobeil, S.; Montefiori, D. C.; Korber, B.; Saunders, K. O.; Haynes, B. F.; Haynes, B. F.; Henderson, R.; Acharya, P.

10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-03-12

3269 De novo assembly and characterization of a highly degenerated ZW sex chromosome in the fish Megaleporinus macrocephalus

Borges, C. H. d. S.; Utsunomia, R.; Varani, A. M.; Uliano da Silva, M.; Guerra, L. V.; Butzge, A. J.; Gomez Agudelo, J. F.; Manso, S.; Freitas, M. V.; Ariede, R. B.; Mastrochirico-Filho, V. A.; Penaloza, C.; Barria, A.; Porto-Foresti, F.; Foresti, F.; Hattori, R. S.; Guiguen, Y.; Houston, R. D.; Hashimoto, D. T.

10.1101/2024.03.07.583869 — genomics — Posted on 2024-03-12

3270 Genomics of Natural Populations: Gene Conversion Events Reveal Selected Genes within the Inversions of Drosophila pseudoobscura

Schaeffer, S. W.; Richards, S.; Fuller, Z. L.

10.1101/2022.08.15.503618 — evolutionary biology — Posted on 2024-03-12

3271 Genomic consequences of isolation and inbreeding in an island dingo population

Leon-Apodaca, A. V.; Kumar, M.; del Castillo, A.; Conroy, G. C.; Lamont, R. W.; Ogbourne, S.; Cairns, K. M.; Borburgh, L.; Behrendorff, L.; Subramanian, S.; Szpiech, Z. A.

10.1101/2023.09.15.557950 — evolutionary biology — Posted on 2024-03-12

3272 Directional swimming patterns in jellyfish aggregations

Malul, D.; Berman, H.; Solodoch, A.; Tal, O.; Barak, N.; Mizrahi, G.; Berenshtein, I.; Toledo, Y.; Lotan, T.; Sher, D. J.; Shavit, U.; Lehahn, Y.

10.1101/2024.03.08.584080 — ecology — Posted on 2024-03-12

3273 Growing older, growing more diverse: sea turtles and epibiotic cyanobacteria

Kanjer, L.; Filek, K.; Mucko, M.; Zekan Lupic, M.; Frleta-Valic, M.; Gracan, R.; Bosak, S.

10.1101/2024.03.08.584065 — ecology — Posted on 2024-03-12

3274 Two opposing roles for Bmp signalling in the development of electrosensory lateral line organs

Campbell, A. S.; Minarik, M.; Franek, R.; Fucikova, M.; Havelka, M.; Gela, D.; Psenicka, M.; Baker, C. V. H.

10.1101/2024.03.07.583945 — developmental biology — Posted on 2024-03-12

3275 A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

Fang, J.; Hatch, C. J.; Andrejecsk, J.; Van Trigt, W.; Juat, D. J.; Chen, Y.-H.; Matsumoto, S.; Lee, A. P.; Hughes, C. C.

10.1101/2024.03.11.584490 — cell biology — Posted on 2024-03-12

3276 Computational Tools for the Analysis of Meiotic Prophase I Images

Crichton, J. H.; Adams, I. R.

10.1101/2023.11.15.567191 — cell biology — Posted on 2024-03-12

3277 A Novel Cell Culture Scratch Assay Platform Generates Reproducible Gaps for Quantitative Cell Movement-Based Studies

Wolpert, N.; Gollahon, L. S.

10.1101/2024.03.11.584450 — cell biology — Posted on 2024-03-12

3278 Enhanced tameness by Limosilactobacillus reuteri from gut microbiota of selectively bred mice

Biswa, B. B.; Mori, H.; Toyoda, A.; Kurokawa, K.; Koide, T.

10.1101/2024.03.11.584526 — microbiology — Posted on 2024-03-12

3279 Allosteric adaptation in the stator complex rescues bacterial motility in Exb/Mot chimeras.

Ridone, P.; Baker, M. A.

10.1101/2024.03.12.584617 — microbiology — Posted on 2024-03-12

3280 Brain-Penetrant NF-κB and NLRP3 Targeting Nanoligomers are Therapeutic in Amyotrophic Lateral Sclerosis (ALS) and Alzheimers Disease (AD) Human Organoid and Mouse Models

Sharma, S.; Wahl, D.; Risen, S.; Gilberto, V. S.; Chatterjee, A.; Moreno, J.; LaRocca, T.; Nagpal, P.

10.1101/2024.03.07.583991 — neuroscience — Posted on 2024-03-12

3281 Beyond functional connectivity: deep learning applied to resting-state fMRI time series in the prediction of 58 human traits in the HCP

Vieira, B. H.; Schöttner, M.; Calhoun, V. D.; Salmon, C. E. G.

10.1101/2024.03.07.583858 — neuroscience — Posted on 2024-03-12

3282 Creativity involves the subjective valuation of ideas via the Brain Valuation System.

Moreno-Rodriguez, S.; Beranger, B.; Volle, E.; Lopez-Persem, A.

10.1101/2024.03.07.583926 — neuroscience — Posted on 2024-03-12

3283 PET Imaging of the Serotonin 1A Receptor in Major Depressive Disorder: Hierarchical Multivariate Analysis of 11CWAY100635 Overcomes Outcome Measure Discrepancies

Matheson, G. J.; Zanderigo, F.; Miller, J. M.; Bartlett, E. A.; Mann, J. J.; Ogden, R. T.

10.1101/2024.03.12.584569 — neuroscience — Posted on 2024-03-12

3284 DiDBiT-TMT: A novel method to quantify changes in the proteomic landscape induced by neural plasticity

Gamaleldin, M.; Yu, N.-K.; Diedrich, J.; Ma, Y.; Wienand, A.; McClatchy, D.; Nykjaer, A.; Nabavi, S.; Yates, J. R.

10.1101/2024.03.07.583889 — neuroscience — Posted on 2024-03-12

3285 The unexplored diversity of wild lupins provides rich genomic resources and insights into lupin evolution

Susek, K.; Franco, E.; Tomaszewska, M.; Kroc, M.; Jamil, H.; Tanwar, U.; Nelson, M. N.; Papa, R.; Delledonne, M.; Jackson, S. A.

10.1101/2024.03.07.583883 — plant biology — Posted on 2024-03-12

3286 Cell-type-specific nuclear morphology predicts genomic instability and prognosis in multiple cancer types

Abel, J.; Jain, S.; Rajan, D.; Padigela, H.; Leidal, K.; Prakash, A.; Conway, J.; Nercessian, M.; Kirkup, C.; Javed, S. A.; Biju, R.; Harguindeguy, N.; Shenker, D.; Indorf, N.; Sanghavi, D.; Egger, R.; Trotter, B.; Gerardin, Y.; Brosnan-Cashman, J. A.; Dhoot, A.; Montalto, M. C.; Parmar, C.; Wapinski, I.; Khosla, A.; Drage, M. G.; Yu, L.; Taylor-Weiner, A.

10.1101/2023.05.15.539600 — cancer biology — Posted on 2024-03-12

3287 Targeted Proteomics of Plasma Extracellular Vesicles Uncovers MUC1 as Combinatorial Biomarker for the Early Detection of High-grade Serous Ovarian Cancer

Cooper, T. T.; Dieters-Castator, D. Z.; Liu, J.; Siegers, G. M.; Veliz, L.; Pink, D.; Lewis, J. D.; Fu, Y.; Lagugne-Labarthet, F.; Steed, H.; Lajoie, G. A.; Postovit, L. M.

10.1101/2022.03.31.486596 — cancer biology — Posted on 2024-03-12

3288 Scaling of stochastic growth and division dynamics: A comparative study of individual rod-shaped cells in the Mother Machine and SChemostat platforms

Ziegler, K. F.; Joshi, K.; Wright, C. S.; Roy, S.; Caruso, W.; Biswas, R. R.; Iyer-Biswas, S.

10.1101/2023.11.23.568485 — biophysics — Posted on 2024-03-12

3289 VISUALIZING THE NUCLEATING AND CAPPED STATES OF F-ACTIN BY Ca2+-GELSOLIN: SAXS DATA BASED STRUCTURES OF BINARY AND TERNARY COMPLEXES

Sagar, A.; Peddada, N.; CHOUDHARY, V.; Mir, Y.; Garg, R.; Ashish, F.

10.1101/2024.03.09.584204 — biophysics — Posted on 2024-03-12

3290 Structural insights into physiological activation and antagonism of melanin-concentrating hormone receptor MCHR1

Ye, X.; Liu, G.; Li, X.; He, B.; Tao, Y.; Gong, W.; Liu, H.

10.1101/2024.03.12.584619 — biophysics — Posted on 2024-03-12

3291 SPARTA: Interpretable functional classification of microbiomes and detection of hidden cumulative effects.

Ruiz, B.; Belcour, A.; Blanquart, S.; Buffet-Bataillon, S.; Le Huerou-Luron, I.; Siegel, A.; Le Cunff, Y.

10.1101/2024.03.07.583888 — bioinformatics — Posted on 2024-03-12

3292 CLCluster: a redundancy-reduction contrastive learning-based clustering method of cancer subtype based on multi-omics data

Wang, H.; Zhang, Y.; Li, W.; Wang, Z.; Li, Z.; Yang, M.

10.1101/2024.03.07.584010 — bioinformatics — Posted on 2024-03-12

3293 Autoencoder-transformed transcriptome improves genotype-phenotype association studies

Li, Q.; Bian, J.; Weeraman, J.; Leung, A.; Yang, G.; Chekouo, T.; Yan, J.; Wu, J.; Long, Q.

10.1101/2023.07.23.550223 — bioinformatics — Posted on 2024-03-12

3294 3DCellComposer - A Versatile Pipeline Utilizing 2D Cell Segmentation Methods for 3D Cell Segmentation

Chen, H.; Murphy, R. F.

10.1101/2024.03.08.584082 — bioinformatics — Posted on 2024-03-12

3295 Inter-modality source coupling: a fully- automated whole-brain data-driven structure- function fingerprint shows replicable links to reading in a large-scale (N~8K) analysis

Kotoski, A.; Liu, J.; Morris, R.; Calhoun, V.

10.1101/2024.03.07.583896 — bioengineering — Posted on 2024-03-12

3296 Metabolism of FAD, FMN and riboflavin (vitamin B2) in the human parasitic blood fluke Schistosoma mansoni

Da'dara, A.; Nation, C.; Skelly, P.

10.1101/2024.03.12.584659 — biochemistry — Posted on 2024-03-12

3297 Estimating evolutionary and demographic parameters via ARG-derived IBD

Huang, Z.; Chan, Y.-b.; Balding, D.; Kelleher, J.

10.1101/2024.03.07.583855 — genetics — Posted on 2024-03-12

3298 Loss of Bbs8 leads to cystic kidney disease in mice and affects tubulin acetylation through HDAC2

Kieckhoefer, E.; Matthiessen, P. A.; Ebert, L. K.; Klausen, C.; Wachten, D.; Benzing, T.; May-Simera, H. L.; Schermer, B.

10.1101/2024.03.07.583949 — genetics — Posted on 2024-03-12

3299 Putative Looping Factor ZNF143/ZFP143 is an Essential Transcriptional Regulator with No Looping Function

Narducci, D. N.; Hansen, A. S.

10.1101/2024.03.08.583987 — genetics — Posted on 2024-03-12

3300 Prioritizing the Valorization Strategies of an Invasive Fern (Azolla) in a Wetland

Nikkhah Kolachahi, F.; Ramezanian, M. R.; Rosentrater, K. A.

10.1101/2024.03.07.583895 — ecology — Posted on 2024-03-12

3301 Requirement of Nek2a and cyclin A2 for Wapl-dependent removal of cohesin from prophase chromatin

Hellmuth, S.; Stemmann, O.

10.1101/2024.03.12.584565 — cell biology — Posted on 2024-03-12

3302 Regulatory Dynamics of Sch9 in Response to Cytosolic Acidification: From Spatial Reconfiguration to Cellular Adaptation to Stresses

Fujii, R.; Takeda, E.; Itakura, E.; Matsuura, A.

10.1101/2024.03.12.584575 — cell biology — Posted on 2024-03-12

3303 Establishing a method for the cryopreservation of viable peripheral blood mononuclear cells in the International Space Station

Ishii, H.; Endo, R.; Hamanaka, S.; Hidaka, N.; Miyauchi, M.; Hagiwara, N.; Miyao, T.; Yamamori, T.; Aiba, T.; Akiyama, N.; Akiyama, T.

10.1101/2024.03.12.584560 — cell biology — Posted on 2024-03-12

3304 Regulation of Interstitial Lung Diseases by Pulmonary Endothelial Cells via PLVAP

Zhang, X.; Jia, L.; Hou, R.; Zhao, Y.-a.; Zhang, L.; Tong, X.; Mo, Y.; Zhang, L.

10.1101/2024.03.12.584592 — cell biology — Posted on 2024-03-12

3305 Effect of Electroacupuncture Pretreatment on Cognitive Impairment and Mitophagy in Aging Model Rats and its mechanism

Liu, B.; Tan, T.; Liu, J.; Li, Z.; Qiu, S.; Xiong, C.; Liu, Q.; Li, J.; Li, Y.; Feng, Q.

10.1101/2024.03.09.584137 — cell biology — Posted on 2024-03-12

3306 Inhibition of Streptococcus pyogenes biofilm by Lactiplantibacillus plantarum and Lacticaseibacillus rhamnosus

Gomez-Mejia, A.; Orlietti, M.; Tarnutzer, A.; Mairpady Shambat, S.; Zinkernagel, A. S.

10.1101/2024.03.12.584618 — microbiology — Posted on 2024-03-12

3307 Pyruvate Kinase M2 regulates Japanese encephalitis virus replication by interacting with NS1 protein

Bohara, V. S.; Deshmukh, A.; Kumar, S.

10.1101/2024.03.12.584590 — microbiology — Posted on 2024-03-12

3308 Distribution-driven disturbance of a molecular community: a theoretical framework

Ramirez, G. A.; Mel, G. C.

10.1101/2024.03.11.584481 — microbiology — Posted on 2024-03-12

3309 Inhibition of NFAT promotes loss of tissue resident uterine natural killer cells and attendant pregnancy complications in humans

Asiimwe, R.; Knott, B.; Greene, M. E.; Wright, E.; Bell, M.; Epstein, D.; Yates, S. D.; Cheung, M. D.; Gonzalez, M. V.; Fry, S.; Boydston, E.; Clevenger, S.; Locke, J. E.; George, J. F.; Burney, R.; Arora, N.; Duncan, V. E.; Richter, H. E.; Gunn, D.; Freud, A. G.; Little, S. C.; Porrett, P. M.

10.1101/2024.03.07.583906 — immunology — Posted on 2024-03-12

3310 The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness

Zeng, H.; Zhu, X.; Wu, Y.; Li, Y.; Zhou, X.; Watzlawik, J.; Chen, Y. M.; Raybuck, A.; Billadeau, D.; Shapiro, V.; Springer, W.; Sun, J.; Boothby, M. R.

10.1101/2024.02.26.582122 — immunology — Posted on 2024-03-12

3311 Differential predictive value of resident memory CD8+T cell subpopulations in non-small-cell lung cancer patients treated by immunotherapy

Paolini, L.; Tran, T.; Corgnac, S.; VILLEMIN, J.-P.; Wislez, M.; Arrondeau, J.; Johannes, L.; Ulmer, J.; Vieillard, L.-V.; Pineau, J.; Gey, A.; Quiniou, V.; Barennes, P.; Pham, H. P.; Gruel, n.; Hasan, M.; Libri, V.; Mella, S.; de Percin, S.; Boudou-Rouquette, P.; Cremer, I.; Blons, h.; Leroy, K.; Laurent-Puig, P.; De Saint Basile, H.; Gibault, L.; Patrice, R.; Mami-Chouaib, F.; Goldwasser, F.; Fabre, E.; Damotte, D.; TARTOUR, E.

10.1101/2024.03.07.583820 — immunology — Posted on 2024-03-12

3312 Microsaccadic suppression of peripheral perceptual detection performance as a function of foveated visual image appearance

Greilich, J.; Hafed, Z. M.

10.1101/2024.03.07.583880 — neuroscience — Posted on 2024-03-12

3313 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations

Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.

10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-12

3314 The Functional Role of Pinwheel Topology in the Primary Visual Cortex of High-Order Animals for Complex Natural Image Representation

Wang, H.; Zhong, H.; Dai, W. P.; Yu, Y.

10.1101/2024.03.07.583885 — neuroscience — Posted on 2024-03-12

3315 The Ramp protocol: uncovering individual differences in walking to an auditory beat using TeensyStep

Zagala, A.; Foster, N. E. V.; van Vugt, F. T.; Dal Maso, F.; Dalla Bella, S.

10.1101/2024.03.07.583713 — neuroscience — Posted on 2024-03-12

3316 Spatially conserved pathoprotein profiling in the human suprachiasmatic nucleus in progressive Alzheimer disease stages

Son, G.; Mladinov, M.; Pereira, F.; Li, S. H.; Tu, C.-L.; Judge, G.; Yang, Y.; Suemoto, C.; Leite, R.; Paes, V.; Pasqualucci, C.; Jacob-Filho, W.; Spina, S.; Seeley, W.; Chang, W.; Neylan, T.; Grinberg, L. T.

10.1101/2024.03.07.584000 — neuroscience — Posted on 2024-03-12

3317 The heritability and structural correlates of brain entropy

Zhen, Y.; Yang, Y.; Zheng, Y.; Wang, X.; Liu, L.; Zheng, Z.; Zheng, H.; Tang, S.

10.1101/2024.03.07.583865 — neuroscience — Posted on 2024-03-12

3318 Distinct streams for supervised and unsupervised learning in the visual cortex

Zhong, L.; Baptista, S.; Gattoni, R.; Arnold, J.; Flickinger, D.; Stringer, C.; Pachitariu, M.

10.1101/2024.02.25.581990 — neuroscience — Posted on 2024-03-12

3319 Synaptic plasticity in human thalamocortical assembloids

Patton, M. H.; Thomas, K. T.; Bayazitov, I. T.; Newman, K. D.; Kurtz, N. B.; Robinson, C. G.; Ramirez, C. A.; Trevisan, A. J.; Bikoff, J. B.; Peters, S. T.; Pruett-Miller, S. M.; Jiang, Y.; Schild, A. B.; Nityanandam, A.; Zakharenko, S. S.

10.1101/2024.02.01.578421 — neuroscience — Posted on 2024-03-12

3320 Clinical factors associated with SFTS diagnosis and severity in cats

Osako, H.; Xu, Q.; Nabashima, T.; Balingit, J. C.; Nwe, K. M.; Yu, F.; Inoue, S.; Hayasaka, D.; Tun, M. M. N.; Morita, K.; Takamatsu, Y.

10.1101/2024.03.06.583784 — zoology — Posted on 2024-03-12

3321 A simple regulatory network coordinates a bacterial stress response in space and time

Choudhary, D.; Foster, K. R.; Uphoff, S.

10.1101/2024.03.07.583862 — systems biology — Posted on 2024-03-12

3322 Rice OsPLATZ3 controls ROS homeostasis by inhibiting ROS-Scavenging Activity during Tapetum Degeneration

Li, Y.; Wang, J.; Tang, F.; Li, L.; Cheng, X.; Sun, X.; Yu, S.; Xia, P.; Wang, Y.; Tong, M.; Cheng, L.

10.1101/2024.03.04.583394 — plant biology — Posted on 2024-03-12

3323 The Zinc Finger protein SlZFP2 is essential for tomato fruit locular tissue morphogenesis

Hoang, G.; Jorly, J.; Constantinescu, D.; Martin, P. G.; Gadin, S.; Mauxion, J.-P.; Bres, C.; Garcia, V.; Gonzalez, N.; Rothan, C.; Bertin, N.; Fernandez-Lochu, L.; Lemaire-Chamley, M.

10.1101/2024.03.07.582990 — plant biology — Posted on 2024-03-12

3324 Bridging fungal resistance and plant growth through constitutive overexpression of Thchit42 gene in Pelargonium graveolens

Rahman, L. U.; Khatoon, K.; Warsi, Z. I.; Singh, A.; Singh, K.; Khan, F.; Singh, P.; Shukla, R.; Verma, R.; Singh, M.; Verma, S. K.; Husain, Z.; Parween, G.; Singh, P.; Azmi, S.

10.1101/2024.03.07.583846 — plant biology — Posted on 2024-03-12

3325 Comparative transcriptomic and lipidomic analysis of fatty acid accumulation in three Camellia oleifera varieties during maturation

Yang, d.; Wang, R.; Lai, H.; Chen, Y.; He, Y.; Xun, C.; Zhang, Y.; He, Z.

10.1101/2024.03.07.583840 — plant biology — Posted on 2024-03-12

3326 Deletion of Robo4 worsens neuroinflammation and motor coordination in a mouse model of Alzheimer's disease

Cullen, A. E.; Winder, N.; Lee, B.; Krishna Kumaran, S.; Arora, N.; Wolf, J.; Woltjer, R.; Walker, A.

10.1101/2024.03.07.583582 — physiology — Posted on 2024-03-12

3327 Bridging geometric morphometrics to medical anatomy: An example from an experimental study of the human smile

Bookstein, F. L.; Kent, J. T.; Khambay, B. S.; Mardia, K. V.

10.1101/2024.03.07.583999 — physiology — Posted on 2024-03-12

3328 Nucleobindin-1 (Nucb1) disruption affects feeding, metabolism, and glucose homeostasis in mice in an age-, sex-, diet- and light cycle-dependent manner

Nasri, A.; Velez, E. J.; Rajeswari, J. J.; Hatef, A.; Unniappan, S.

10.1101/2024.03.07.584005 — physiology — Posted on 2024-03-12

3329 Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells

Thouverey, C.; Apostolides, P.; Brun, J.; Caverzasio, J.; Ferrari, S.

10.1101/2023.09.11.557168 — pharmacology and toxicology — Posted on 2024-03-12

3330 miR-644a is a tumor cell-intrinsic mediator of sex bias in glioblastoma

Hong, E. S.; Wang, S. Z.; Ponti, A. K.; Hajdari, N.; Lee, J.; Mulkearns-Hubert, E. E.; Volovetz, J.; Kay, K. E.; Lathia, J.; Dhawan, A.

10.1101/2024.03.11.584443 — cancer biology — Posted on 2024-03-12

3331 Functional transcriptional signatures for tumor-type-agnostic phenotype prediction

Weistuch, C.; Murgas, K. A.; Zhu, J.; Norton, L.; Dill, K. A.; Tannenbaum, A. R.; Deasy, J. O.

10.1101/2023.04.12.536595 — cancer biology — Posted on 2024-03-12

3332 Competitive assembly resolves the stoichiometry of essential proteins in infectious HIV-1 virions.

Durden, H.; Preece, B.; Gallegos, R.; Saha, I.; MacArthur, B.; Petersen, A.; Peppel, W.; Saffarian, S.

10.1101/2024.03.10.584319 — biophysics — Posted on 2024-03-12

3333 IP6 and PF74 affect HIV-1 Capsid Stability through Modulation of Hexamer-Hexamer Tilt Angle Preference

Garza, C. M.; Holcomb, M.; Santos-Martins, D.; Torbett, B. E.; Forli, S.

10.1101/2024.03.11.584513 — biophysics — Posted on 2024-03-12

3334 Mechanistic insights into transport models of the sphingolipid transport protein, Spinster homolog 2 (Spns2), using MD simulations

Sharp, A. K.; LoPresti, M. Q.; Brown, A. M.

10.1101/2024.03.10.584301 — biophysics — Posted on 2024-03-12

3335 DNA replication and polymer chain duplication reshape the genome in space and time

D'Asaro, D.; Tortora, M. M.; Vaillant, C.; Arbona, J.-M.; Jost, D.

10.1101/2024.03.12.584628 — biophysics — Posted on 2024-03-12

3336 Controlling Drug Partitioning in Individual Protein Condensates through Laser-Induced Microscale Phase Transitions.

Leppert, A.; Jianhui, F.; Railaite, V.; Bohn Pessatti, T.; Morman, C.; Osterholz, H.; Maia, F. R. N. C.; Linder, M. B.; Rising, A.; Landreh, M.

10.1101/2024.03.12.584573 — biophysics — Posted on 2024-03-12

3337 A subtle modification of modafinil-based DAT inhibitors changes conformational preference

Lee, K. H.; Camacho-Hernandez, G. A.; Newman, A. H.; Shi, L.

10.1101/2024.03.06.583808 — biophysics — Posted on 2024-03-12

3338 Labeling Natural Killer cells with superparamagnetic iron oxide nanoparticles for detection by preclinical and clinical-scale magnetic particle imaging

Sehl, O. C.; Yang, Y.; Anjier, A. R.; Nevozhay, D.; Cheng, D.; Guo, K.; Fellows, B.; Mohtasebzadeh, A. R.; Mason, E. E.; Sanders, T.; Kim, P.; Trease, D.; Koul, D.; Goodwill, P. W.; Sokolov, K.; Wintermark, M.; Gordon, N.; Greve, J. M.; Gopalakrishnan, V.

10.1101/2024.03.08.583881 — biophysics — Posted on 2024-03-12

3339 Evolutionary sequence and structural basis for the distinct conformational landscapes of Tyr and Ser/Thr kinases

Gizzio, J.; Thakur, A.; Haldane, A.; Levy, R.

10.1101/2024.03.08.584161 — biophysics — Posted on 2024-03-12

3340 Understanding the binding mechanisms of Alzheimer risk factor TREM2 in lipid bilayer using multi-scale molecular dynamics simulations

Zhong, Z.; Ulmschneider, M.; Lorenz, C.

10.1101/2024.03.08.584168 — biophysics — Posted on 2024-03-12

3341 Tipping-point transition from transient to persistent inflammation in pancreatic islets

Hansen, T. H.; Nielsen, P. Y.; Jensen, M. H.; Mandrup-Poulsen, T.; Trusina, A.

10.1101/2024.03.10.584271 — biophysics — Posted on 2024-03-12

3342 DNA-based ForceChrono Probes for Deciphering Single-Molecule Force Dynamics in Living Cells

Hu, Y.; Li, H.; Zhang, C.; Feng, J.; Wang, W.; Chen, W.; Yu, M.; Zhang, X.; Liu, Z.

10.1101/2024.03.09.584267 — biophysics — Posted on 2024-03-12

3343 Molecular mechanism of parental H3/H4 recycling at a replication fork

Nagae, F.; Murayama, Y.; Terakawa, T.

10.1101/2024.03.07.583824 — biophysics — Posted on 2024-03-12

3344 A Way to Understand Dynamics of Infantile Myoclonic Encephalopathy

Verma, V.

10.1101/2024.03.10.583151 — biophysics — Posted on 2024-03-12

3345 Dilated cardiomyopathy-associated skeletal muscle actin (ACTA1) mutation R256H disrupts actin structure and function and causes cardiomyocyte hypocontractility

Garg, A.; Jansen, S.; Zhang, R.; Lavine, K.; Greenberg, M. J.

10.1101/2024.03.10.583979 — biophysics — Posted on 2024-03-12

3346 Post-Translational Modifications Control Phase Transitions of Tau

Powell, W.; Nahum, M.; Pankratz, K.; Herlory, M.; Greenwood, J.; Poliyenko, D.; Holland, P.; Jing, R.; Biggerstaff, L.; Stowell, M.; Walczak, M.

10.1101/2024.03.08.583040 — biophysics — Posted on 2024-03-12

3347 Fatiguing Exercise Reduces Cellular Passive Young's Modulus in Human Vastus Lateralis Muscle

Privett, G. E.; Ricci, A. W.; David, L.; Needham, K. W.; Tan, Y. H.; Nakayama, K. H.; Callahan, D. M.

10.1101/2024.03.07.583989 — biophysics — Posted on 2024-03-12

3348 Comparative Pore Structure and Dynamics for Bacterial Microcompartment Shell Protein Assemblies in Sheets or Shells

Raza, S.; Sarkar, D.; Chan, L. J. G.; Mae, J.; Sutter, M.; Petzold, C. J.; Kerfeld, C. A.; Ralston, C. Y.; Gupta, S.; Vermaas, J. V.

10.1101/2024.03.12.584231 — biophysics — Posted on 2024-03-12

3349 Rotamer Density Estimator is an Unsupervised Learner of the Effect of Mutations on Protein-Protein Interaction

Luo, S.; Su, Y.; Wu, Z.; Su, C.; Peng, J.; Ma, J.

10.1101/2023.02.28.530137 — bioinformatics — Posted on 2024-03-12

3350 Protein language models are biased by unequal sequence sampling across the tree of life

Ding, F.; Steinhardt, J. N.

10.1101/2024.03.07.584001 — bioinformatics — Posted on 2024-03-12

3351 Integrating spatial transcriptomics count data with Crescendo improves visualization and detection of spatial gene patterns

Millard, N.; Chen, J. H.; Palshikar, M. G.; Pelka, K.; Spurrell, M.; Price, C.; He, J.; Hacohen, N.; Raychaudhuri, S.; Korsunsky, I.

10.1101/2024.03.07.583997 — bioinformatics — Posted on 2024-03-12

3352 Sustained neurotrophic factor cotreatment enhances donor and host retinal ganglion cell survival in mice

Soucy, J. R.; Kriukov, E.; Oswald, J.; Masland, J.; Pernstich, C.; Baranov, P.

10.1101/2024.03.07.583961 — bioengineering — Posted on 2024-03-12

3353 Scalable Isolation of Surface-Engineered Extracellular Vesicles and Separation of Free Proteins via Tangential Flow Filtration and Size Exclusion Chromatography (TFF-SEC)

Kawai-Harada, Y.; Nimmagadda, V.; Harada, M.

10.1101/2024.03.07.584007 — bioengineering — Posted on 2024-03-12

3354 An engineered human cardiac tissue model reveals contributions of systemic lupus erythematosus autoantibodies to myocardial injury

Fleischer, S.; Nash, T. R.; Tamargo, M. A.; Lock, R. I.; Venturini, G.; Morsink, M.; Li, V.; Lamberti, M. J.; Graney, P. L.; Liberman, M.; Kim, Y.; Zhuang, R. Z.; Whitehead, J.; Friedman, R. A.; SONI, R.; Seidman, J. G.; Seidman, C. E.; Geraldino-Pardilla, L.; Winchester, R.; Vunjak-Novakovic, G.

10.1101/2024.03.07.583787 — bioengineering — Posted on 2024-03-12

3355 Enhancing viscosity control in antibody formulations: A framework for the biophysical screening of mutations targeting solvent-accessible hydrophobic and electrostatic patches

Armstrong, G. B.; Shah, V.; Sanches, P.; Patel, M.; Casey, R.; Jamieson, C. J.; Burley, G. A.; Lewis, W. J.; Rattray, Z.

10.1101/2024.03.07.583917 — bioengineering — Posted on 2024-03-12

3356 A cryopreservation strategy for myoblast storage in paper-based scaffolds for inter-laboratory studies of skeletal muscle health

Rjaibi, S.; Jacques, E.; Ni, C.; Xu, B.; Kouthouridis, S.; Sitolle, J.; Lad, h.; Gulati, N.; Li, N. T.; Ahn, H.; Ginsberg, H.; Zhang, B.; Le-Grand, F.; Gilbert, P. M.; McGuigan, A. P.

10.1101/2024.03.07.583636 — bioengineering — Posted on 2024-03-12

3357 High-throughput determination of RNA tertiary contact thermodynamics by quantitative DMS chemical mapping

Lange, B. W.; Gil, R. G.; Yesselman, J. D.

10.1101/2024.03.11.584472 — biochemistry — Posted on 2024-03-12

3358 Phenylphenalenones and Linear Diarylheptanoid Derivatives are Biosynthesized via Parallel Routes in Musella lasiocarpa, the Chinese Dwarf Banana

Lyu, H.; Ernst, L.; Nakamura, Y.; Okamura, Y.; Koellner, T.; Luck, K.; Liu, B.; Chen, Y.; Beerhues, L.; Gershenzon, J.; Paetz, C.

10.1101/2024.03.11.584385 — biochemistry — Posted on 2024-03-12

3359 Molecular mechanism for regulating APOBEC3G DNA editing function by the non-catalytic domain

Yang, H.; Pacheco, J.; Kim, K.; Ebrahimi, D.; Ito, F.; Chen, X. S.

10.1101/2024.03.11.584510 — biochemistry — Posted on 2024-03-12

3360 The carrier proteome limit should be reassessed for each mass analyzer architecture

Orsburn, B.

10.1101/2024.03.08.584130 — biochemistry — Posted on 2024-03-12

3361 Exploring RNA modifications in infectious non-coding circular RNAs

Vopalensky, P.; Skriba, A.; Chiumenti, M.; Duricekova, L.; Simonova, A.; Luksan, O.; Di Serio, F.; Navarro, B.; Cahova, H.

10.1101/2024.03.12.584625 — biochemistry — Posted on 2024-03-12

3362 Interpersonal heart rate synchrony predicts effective information processing in a naturalistic group decision-making task

Sharika, K. M.; Thaikkandi, S.; Nivedita, ; Platt, M.

10.1101/2023.07.24.550277 — animal behavior and cognition — Posted on 2024-03-12

3363 Patterns of neuronal activation following ethanol-induced social facilitation and social inhibition in adolescent cFos-LacZ male and female rats

Towner, T.; Applegate, D. T.; Varlinskaya, E. I.; Coleman, H. J.; Werner, D.

10.1101/2024.03.06.583793 — animal behavior and cognition — Posted on 2024-03-12

3364 Inference of Transcriptional Regulation From STARR-seq Data

Safaeesirat, A.; Taeb, H.; Tekoglu, E.; Morova, T.; Lack, N.; Emberly, E.

10.1101/2024.03.06.583826 — genomics — Posted on 2024-03-12

3365 IQCH regulates spermatogenesis by interacting with CaM to promote the expression of RNA-binding proteins

Ruan, T.; Zhou, R.; Yang, Y.; Guo, J.; Jiang, C.; Wang, X.; Shen, G.; Dai, S.; Chen, S.; Shen, Y.

10.1101/2023.06.23.546221 — genetics — Posted on 2024-03-12

3366 Demographic history and the efficacy of selection in the globally invasive mosquito Aedes aegypti

Kent, T.; Schrider, D.; Matute, D. R.

10.1101/2024.03.07.584008 — evolutionary biology — Posted on 2024-03-12

3367 Natural slab photonic crystals and where to find them among the girdle bands of diatoms

Ashworth, M. P.; Lam, D. W.; Lopez-Garcia, M.; Manning, S. R.; Goessling, J. W.

10.1101/2024.03.08.584047 — evolutionary biology — Posted on 2024-03-12

3368 Adaptive generalization in pollinators: hawkmoths increase fitness to long-tubed flowers, but secondary pollinators remain important

Wenzell, K. E.; Zhang, J. Y.; Skogen, K. A.; Fant, J. B.

10.1101/2024.03.08.584170 — evolutionary biology — Posted on 2024-03-12

3369 Functional Diversification of Gene Duplicates under the Constraint of Protein Structure

guo, k.; yang, y.; you, t.; zhu, k.

10.1101/2024.03.06.583810 — evolutionary biology — Posted on 2024-03-12

3370 Gliding towards an understanding of the origin of flight in bats

Burtner, A. E.; Grossnickle, D. M.; Santana, S. E.; Law, C. J.

10.1101/2022.09.26.509622 — evolutionary biology — Posted on 2024-03-12

3371 Changes in plant physiology during cultivation periods influence the hydrogen isotope ratio of the water-insect relationship

Fujii, T.; Akiduki, G.; Yabusaki, S.; Tayasu, I.

10.1101/2024.03.06.583809 — ecology — Posted on 2024-03-12

3372 Predicting species distributions in the open ocean with convolutional neural networks.

Morand, G.; Joly, A.; Rouyer, T.; Lorieul, T.; Barde, J.

10.1101/2023.08.11.551418 — ecology — Posted on 2024-03-12

3373 Cool ocean temperatures fail to buffer the impacts of heat exposure during low tide on the behaviour and physiology of a keystone predator

Walton, L. N.; Watts, V. R.; Schuster, J. M.; Bates, A. E.

10.1101/2024.03.07.584009 — ecology — Posted on 2024-03-12

3374 Wildlife-vehicle collisions simplify regional food webs

Mestre, F.; Bastazini, V. A. G.; Ascensao, F.

10.1101/2024.03.07.583843 — ecology — Posted on 2024-03-12

3375 Screening of functional maternal-specific chromatin regulators in early embryonic development

Liu, G.; Wang, Y.; Wang, X.; Wang, W.; Cao, Z.; Zhang, Y.

10.1101/2024.03.06.583790 — developmental biology — Posted on 2024-03-12

3376 Sendai virus persistence questions the transient naive reprogramming method for iPSC generation

De Los Angeles, A.; Hug, C. B.; Gladyshev, V. N.; Church, G. M.; Velychko, S.

10.1101/2024.03.07.583804 — developmental biology — Posted on 2024-03-12

3377 cGAS-STING is responsible for aging of telomerase deficient zebrafish.

Serifoglu, N.; Allavena, G.; Bastos-Lopes, B.; Marzullo, M.; Bousounis, P.; Trompouki, E.; Ferreira, M. G.

10.1101/2024.03.11.584360 — cell biology — Posted on 2024-03-12

3378 Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications

Schuster, J.; Lu, X.; Dang, Y.; Klar, J.; Wenz, A.; Dahl, N.; Chen, X.

10.1101/2023.10.10.561691 — cell biology — Posted on 2024-03-12

3379 DetectEV: a functional enzymatic assays to predict the potency of extracellular vesicles

Adamo, G.; Picciotto, S.; Gargano, P.; Paterna, A.; Rao, E.; Raccosta, S.; Romancino, D. P.; Ghersi, G.; Manno, M.; Salamone, M.; Bongiovanni, A.

10.1101/2023.10.24.563745 — cell biology — Posted on 2024-03-12

3380 Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation

Black, E. M.; Ramirez Parrado, C. A.; Trier, I.; Li, W. V.; Joo, Y. K.; Pichurin, J.; Liu, Y.; Kabeche, L.

10.1101/2024.03.08.584115 — cell biology — Posted on 2024-03-12

3381 Cytokine and Chemokine Receptor Profiles in Adipose Tissue Vasculature Unravel Endothelial Cell Responses in HIV

Obare, L. M.; Priest, S.; Ismael, A.; Mashayekhi, M.; Zhang, X.; Stolze, L.; Sheng, Q.; Vue, Z.; Neikirk, K.; Beasley, H.; Gabriel, C.; Temu, T.; Gianella, S.; Mallal, S.; Koethe, J.; Hinton, A.; Bailin, S.; Wanjalla, C. N.

10.1101/2024.03.10.584280 — cell biology — Posted on 2024-03-12

3382 Novel Ser74 of NF-kappaB/CgIkappaBalpha Phosphorylated by MAPK/ERK Regulates Temperature Adaptation in Oysters

Li, L.; Wang, C.; Jiang, Z.; Du, M.; Cong, R.; Wang, W.; Zhang, T.; Chen, J.; Zhang, G.

10.1101/2024.03.11.584362 — cell biology — Posted on 2024-03-12

3383 A consensus motif in ASH1 and further transcripts unifies several RNA motifs required for interaction with the She2p/She3p transport machinery and mRNA localization in yeast

Seiler, M.; Niedner, A.; Heber, S.; Feldbruegge, M.; Jansen, R.-P.; Niessing, D.; Zarnack, K.

10.1101/2024.03.10.584336 — cell biology — Posted on 2024-03-12

3384 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS

Appleton, E. M.; Hong, K.; Rodriguez-Caycedo, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; McNutt, B.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.

10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-12

3385 A Fully-Automated Senescence Test (FAST) for the high-throughput quantification of senescence-associated markers

Neri, F.; Takajjart, S. N.; Lerner, C. A.; Desprez, P.-Y.; Schilling, B.; Campisi, J.; Gerencser, A. A.

10.1101/2023.12.22.573123 — cell biology — Posted on 2024-03-12

3386 Metatranscriptomic Compendium of 55900 RNA Viruses Deciphers Human Health Implication and Ecological roles of RNA Virome in Global Wastewater Treatment Plants

Yuan, L.; Ju, F.

10.1101/2024.03.12.584551 — microbiology — Posted on 2024-03-12

3387 Bacterial strain nomenclature in the genomic era: Life Identification Numbers using a gene-by-gene approach

Palma, F.; Hennart, M.; Jolley, K. A.; Crestani, C.; Wyres, K. L.; Bridel, S.; Yeats, C. A.; Brancotte, B.; Raffestin, B.; David, S.; Lam, M. M. C.; Izdebski, R.; Passet, V.; Rodrigues, C.; Rethoret-Pasty, M.; Maiden, M. C. J.; Aanensen, D. M.; Holt, K. E.; Criscuolo, A.; Brisse, S.

10.1101/2024.03.11.584534 — microbiology — Posted on 2024-03-12

3388 Constitutive immune surveillance of nasal mucosa by three neutrophil subsets with distinct origin, phenotype, and function

Gonzalez, R. J.; Hanc, P.; Alvarez, D.; Kazer, S. W.; Messou, M.-A.; Mazo, I. B.; Matysiak Match, C.; Garg, R.; Helble, J. D.; Pallis, P.; Ende, R.; Basset, A.; Malley, R.; Derre, I.; Starnbach, M. N.; von Andrian, U. H.

10.1101/2024.03.06.583781 — immunology — Posted on 2024-03-12

3389 Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells

Cepika, A.-M.; Amaya, L.; Waichler, C.; Narula, M.; Mantilla, M. M.; Thomas, B. C.; Chen, P. P.; Freeborn, R. A.; Pavel-Dinu, M.; Nideffer, J.; Porteus, M.; Bacchetta, R.; Mueller, F.; Greenleaf, W. J.; Chang, H. Y.; Roncarolo, M. G.

10.1101/2024.03.07.582969 — immunology — Posted on 2024-03-12

3390 INGEsT: An Open-Source Behavioral Setup for Studying Self-motivated Ingestive Behavior and Learned Operant Behavior

Zhao, Z.; Xu, B.; Loomis, C. L.; Anthony, S. A.; McKie, I.; Srigiriraju, A.; Bolton, M.; Stern, S. A.

10.1101/2024.03.10.584229 — neuroscience — Posted on 2024-03-12

3391 Modulation of GABAAreceptor trafficking by WWC2 reveals class-specific mechanisms of synapse regulation by WWC family proteins

Dunham, T. L.; Wilkerson, J. R.; Johnson, R. C.; Huganir, R. L.; Volk, L. J.

10.1101/2024.03.11.584487 — neuroscience — Posted on 2024-03-12

3392 Phosphorylation of PLPPR3 membrane proteins as signaling integrator at neuronal synapses

Kroon, C.; Bareesel, S.; Kirchner, M.; Gimber, N.; Ranti, D.; Brosig, A.; Textoris-Taube, K.; Zolnik, T. A.; Mertins, P.; Schmoranzer, J.; Leondaritis, G.; Eickholt, B.

10.1101/2024.03.11.584206 — neuroscience — Posted on 2024-03-12

3393 AMPA receptor desensitization shapes gain control in the lateral geniculate nucleus

Ruggieri, S.; Gollisch, T.; von Engelhardt, J.

10.1101/2024.03.12.584576 — neuroscience — Posted on 2024-03-12

3394 Rem2 interacts with CaMKII at synapses and restricts long-term potentiation in hippocampus

Anjum, R.; Clarke, V. R. J.; Nagasawa, Y.; Murakoshi, H.; Paradis, S.

10.1101/2024.03.11.584540 — neuroscience — Posted on 2024-03-12

3395 Neural mechanism of rebooting the unconsciousness caused by midazolam

Gu, L.; Shao, W.; Liu, L.; Xu, Q.; Wang, Y.; Gu, J.; Yang, Y.; Zhang, Z.; Wu, Y.; Shen, Y.; Yu, Q.; Lian, X.; Ma, H.; Zhang, Y.; Zhang, H.

10.1101/2023.03.20.533578 — neuroscience — Posted on 2024-03-12

3396 Modeled grid cells aligned by a flexible attractor

Benas, S.; Fernandez, X.; Kropff, E.

10.1101/2022.06.13.495956 — neuroscience — Posted on 2024-03-12

3397 Human assembloid model of the ascending neural sensory pathway

Kim, J.-i.; Imaizumi, K.; Thete, M. V.; Hudacova, Z.; Jurjut, O.; Amin, N. D.; Scherrer, G.; Pasca, S. P.

10.1101/2024.03.11.584539 — neuroscience — Posted on 2024-03-12

3398 NeuralPlayground: A Standardised Environment for Evaluating Models of Hippocampus and Entorhinal Cortex

Domine, C. C. J.; Carrasco Davis, R. A.; Hollingsworth, L.; Sirmpilatze, N.; Tyson, A. L.; Jarvis, D.; Barry, C.; Saxe, A. M.

10.1101/2024.03.06.583699 — neuroscience — Posted on 2024-03-12

3399 The wake and sleep-modulating neurons of the lateral hypothalamic area demonstrate a differential pattern of degeneration in Alzheimers disease

Satpati, A.; Soloviev, A. V.; Pereira, F. L.; Mladinov, M.; Larsen, E.; Leite, R. E. P.; Suemoto, C. K.; Rodriguez, R. D.; Paes, V. R.; Walsh, C.; Spina, S.; Seeley, W. W.; Pasqualucci, C. A.; Filho, W. J.; Neylan, T. C.; Grinberg, L. T.

10.1101/2024.03.06.583765 — neuroscience — Posted on 2024-03-12

3400 Reactive microglia fail to respond to environmental damage signals in a viral-induced mouse model of temporal lobe epilepsy

Wallis, G. J.; Bell, L. A.; Wagner, J. N.; Buxton, L.; Balachandar, L.; Wilcox, K. S.

10.1101/2024.03.06.583768 — neuroscience — Posted on 2024-03-12

3401 Longevity of Implantable Silicon-ICs for Emerging Neural Applications: Evaluation of Bare Die and PDMS-Coated ICs After Accelerated Aging and Implantation Studies

Nanbakhsh, K.; Idil, A. S.; Lamont, C.; Ducso, C.; Akgun, O. C.; Horvath, D.; Toth, K.; Ulbert, I.; Mazza, F.; Constandinou, T.; Serdijn, W. A.; Vanhoestenberghe, A.; Donaldson, N.; Giagka, V.

10.1101/2024.03.06.583769 — neuroscience — Posted on 2024-03-12

3402 Modulation of pedunculopontine input to the basal ganglia relieves motor symptoms in Parkinsonian mice

Lin, C.; Ridder, M.; Zhong, J.; Albornoz, E. A.; Sedlak, P.; Xu, L.; Woodruff, T. M.; Chen, F.; Sah, P.

10.1101/2024.03.06.583786 — neuroscience — Posted on 2024-03-12

3403 Disentangling the spinal mechanisms of illusory heat and burning sensations in the Thermal Grill Illusion

Mitchell, A. G.; Fischer Ehmsen, J.; Elmstrom Christensen, D.; Stuckert, A.; Haggard, P.; Fardo, F.

10.1101/2023.08.24.554485 — neuroscience — Posted on 2024-03-12

3404 3D quantification of viral transduction efficiency in living human retinal organoids

Rogler, T. S.; Salbaum, K. A.; Sonntag, S. M.; James, R.; Shelton, E. R.; Brinkop, A. T.; Klopstock, T.; Babutzka, S.; Michalakis, S.; Serwane, F.

10.1101/2024.03.06.583795 — neuroscience — Posted on 2024-03-12

3405 The neural and computational architecture of feedback dynamics in mouse cortex during stimulus report

Ciceri, S.; Oude Lohuis, M. N.; Rottschafer, V.; Pennartz, C.; Avitabile, D.; van Gaal, S.; Olcese, U.

10.1101/2023.07.19.549692 — neuroscience — Posted on 2024-03-12

3406 NEK1 haploinsufficiency worsens DNA damage but not defective ciliogenesis in C9ORF72 patient-derived iPSC-motoneurons

Santangelo, S.; Invernizzi, S.; Sorce, M. N.; Casiraghi, V.; Peverelli, S.; Brusati, A.; Colombrita, C.; Ticozzi, N.; Silani, V.; Bossolasco, P.; Ratti, A.

10.1101/2024.03.07.582752 — neuroscience — Posted on 2024-03-12

3407 Masitinib Limits Neuronal Damage, as Measured by Serum Neurofilament Light Chain Concentration, in a Model of Neuroimmune-Driven Neurodegenerative Disease

Hermine, O.; Gros, L.; Tran, T.-A.; Loussaief, L.; Flosseau, K.; Moussy, A.; Mansfield, C.; Vermersch, P.

10.1101/2024.03.07.583695 — neuroscience — Posted on 2024-03-12

3408 High-resolution perfusion imaging in rodents using pCASL at 9.4 T

Pires Monteiro, S.; Hirschler, L.; Barbier, E.; Figueiredo, P.; Shemesh, N.

10.1101/2024.03.07.583839 — neuroscience — Posted on 2024-03-12

3409 Cortical lipids containing choline mediate cannabinoid-induced cognitive improvement

Moreno-Rodriguez, M.; Martinez-Gardeazabal, J.; Bengoetxea de Tena, I.; Llorente-Ovejero, A.; Lombardero, L.; Gonzalez de San Roman, E.; Manuel, I.; Gimenez-Llort, L.; Rodriguez-Puertas, R.

10.1101/2024.03.07.583670 — neuroscience — Posted on 2024-03-12

3410 Second language learning in older adults modulates Stroop task performance and brain activation

Schultz, D. H.; Gansemer, A.; Allgood, K.; Gentz, M.; Secilmis, L.; Deldar, Z.; Savage, C. R.; Ghazi Saidi, L.

10.1101/2024.03.07.583963 — neuroscience — Posted on 2024-03-12

3411 Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation

Klokman, G.; Xu, Y.; Bond, K.; Wu, X.; Schustak, J.; Mandelbaum, J.; Twarog, M.; Han, H.; Paulina, M.-K.; Coble, M.; Hayden, C.; Galarneau, J.-R.; Qiu, Y.; Esterberg, R.; Huang, Q.; Saint-Geniez, M.; Aranda, J.; Bao, Y.

10.1101/2024.03.11.584455 — cell biology — Posted on 2024-03-12

3412 Nationwide genome surveillance of carbapenem-resistant Pseudomonas aeruginosa in Japan

Yano, H.; Hayashi, W.; Kawakami, S.; Aoki, S.; Anzai, E.; Zuo, H.; Kitamura, N.; Hirabayashi, A.; Kajihara, T.; Kayama, S.; Sugawara, Y.; Yahara, K.; Sugai, M.

10.1101/2023.12.17.572044 — microbiology — Posted on 2024-03-12

3413 Spatial and temporal pattern of structure-function coupling of human brain connectome with development

Feng, G.; Wang, Y.; Huang, W.; Chen, H.; Cheng, J.; Shu, N.

10.1101/2023.09.11.557107 — neuroscience — Posted on 2024-03-12

3414 The acute effects of cocoa flavanols on cognitive control and response inhibition: A randomised crossover trial

Altinok, A.; Moruzzi, M.; Akyurek, E. G.

10.1101/2024.03.10.584219 — neuroscience — Posted on 2024-03-12

3415 When and why does motor preparation arise in recurrent neural network models of motor control?

Schimel, M.; Kao, T.-C.; Hennequin, G.

10.1101/2023.04.03.535429 — neuroscience — Posted on 2024-03-12

3416 Telomere-to-telomere assembly by preserving contained reads

Kamath, S. S.; Bindra, M.; Pal, D.; Jain, C.

10.1101/2023.11.07.565066 — bioinformatics — Posted on 2024-03-12

3417 SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition

10.1101/2024.02.12.580004 — biochemistry — Posted on 2024-03-12

3418 Providing information about wild animal psychology impacts public attitudes beyond ecological information

Morton, F. B.; Henri, D. C.; Adaway, K. A.; Soulsbury, C. D.; Hopkins, C.

10.1101/2023.11.10.566575 — animal behavior and cognition — Posted on 2024-03-12

3419 Tbx1 haploinsufficiency causes brain metabolic and behavioral anomalies in adult mice which are corrected by vitamin B12 treatment

Caterino, M.; Paris, D.; Torromino, G.; Costanzo, M.; Flore, G.; Tramice, A.; Golini, E.; Mandillo, S.; Cavezza, D.; Angelini, C.; Ruoppolo, M.; Motta, A.; De Leonibus, E.; Baldini, A.; Illingworth, E.; Lania, G.

10.1101/2024.02.01.578212 — genetics — Posted on 2024-03-12

3420 Preventing multiple resistance above all: new insights for managing fungal adaptation

Ballu, A.; Ugazio, C.; Duplaix, C.; Noly, A.; Wullschleger, J.; Torriani, S. F. F.; Deredec, A.; Carpentier, F.; Walker, A.-S.

10.1101/2022.12.17.520869 — evolutionary biology — Posted on 2024-03-12

3421 Gene expression is the main driver of purifying selection in large penguin populations

Trucchi, E.; Massa, P.; Giannelli, F.; Latrille, T.; Fernandes, F. A. N.; Ancona, L.; Stenseth, N. C.; Ferrer Obiol, J.; Paris, J.; Bertorelle, G.; Le Bohec, C.

10.1101/2023.08.08.552445 — evolutionary biology — Posted on 2024-03-12

3422 Sex differences in the relationship between maternal and foetal glucocorticoids in a free-ranging large mammal

Amin, B.; Fishman, R.; Quinn, M.; Matas, D.; Palme, R.; Koren, L.; Ciuti, S.

10.1101/2023.05.04.538920 — ecology — Posted on 2024-03-12

3423 Thymic epithelial organoids mediate T cell development

Hubscher, T.; Lorenzo-Martin, F.; Barthlott, T.; Tillard, L.; Langer, J.; Rouse, P.; Blackburn, C.; Hollander, G. C.; Lutolf, M.

10.1101/2024.03.05.583513 — developmental biology — Posted on 2024-03-12

3424 Reduced Filaggrin expression induces dysregulated intracellular signalling in atopic eczema

Hughes, A. J.; Coppock, L. E.; Tachie-Menson, T.; Thomas, B. R.; Dewan, P.; Doykov, I.; Mills, K.; O'Toole, E. A.; O'Shaughnessy, R. F.

10.1101/2024.03.11.584344 — cell biology — Posted on 2024-03-12

3425 A consensus motif in ASH1 and further transcripts unifies several RNA motifs required for interaction with the She2p/She3p transport machinery and mRNA localization in yeast

Seiler, M.; Niedner, A.; Heber, S.; Feldbruegge, M.; Jansen, R.-P.; Niessing, D.; Zarnack, K.

10.1101/2024.03.10.584336 — cell biology — Posted on 2024-03-12

3426 Smad4 Loss in the Mouse Intestinal Epithelium Alleviates the Pathological Fibrotic Response to Injury in the Colon

Hashemi, Z.; Hui, T.; Wu, A.; Matouba, D.; Zokowski, S.; Nejati, S.; Lim, C.; Bruzzese, J.; Seabold, K.; Mills, C.; Lin, C.; Wrath, K.; Wang, H.; Wang, H.; Verzi, M. P.; Perekatt, A.

10.1101/2024.03.08.578000 — cell biology — Posted on 2024-03-12

3427 Cellular heterogeneity and dynamics of the human uterus in healthy premenopausal women

Ulrich, N. D.; Vargo, A. H.; Ma, Q.; Shen, Y.-C.; Hannum, D. F.; Gurczynski, S. J.; Moore, B. B.; Schon, S.; Lieberman, R.; Shikanov, A.; Marsh, E. E.; Fazleabas, A. T.; Li, J. Z.; Hammoud, S. S.

10.1101/2024.03.07.583985 — cell biology — Posted on 2024-03-12

3428 Gliding motility of the diatom Craspedostauros australis correlates with the intracellular movement of raphid-specific myosins

Davutoglu, M. G.; Geyer, V. F.; Niese, L.; Soltwedel, J. R.; Zoccoler, M. L.; Haase, R.; Kroeger, N.; Diez, S.; Poulsen, N.

10.1101/2024.03.11.584054 — cell biology — Posted on 2024-03-12

3429 Insights into Cellular Evolution: Temporal Deep Learning Models and Analysis for Cell Image Classification

Zhao, X.; de Perez, A. R.; Dimitrova, E. S.; Kemp, M.; Anderson, P. E.

10.1101/2024.03.11.584308 — cell biology — Posted on 2024-03-12

3430 Aberrant Lipid Accumulation leads to Retinal Pigmental Epithelium Dysfunction and Photoreceptor Degeneration in Prcd-deficient mice

Motipally, S. I.; Kolson, D. R.; Guan, T.; Kolandaivelu, S.

10.1101/2024.03.08.584131 — cell biology — Posted on 2024-03-12

3431 Small molecule modulation of insulin receptor-insulin like growth factor-1 receptor heterodimers in human endothelial cells

Myers, C. G.; Viswambharan, H.; Haywood, N.; Bridge, K.; Turvey, S. J.; Armstrong, T.; Lunn, L.; Meakin, P. J.; Clavane, E. M.; Beech, D. J.; Cubbon, R. M.; Wheatcroft, S. B.; McPhillie, M. J.; Issad, T.; Fishwick, C. W.; Kearney, M. T.; Simmons, K. J.

10.1101/2024.03.11.583535 — cell biology — Posted on 2024-03-12

3432 A cellular assay system revealed the deamidase-mediated regulation of the Arg-mediated N-end rule protein degradation pathway

Yoshida, S.; Ohta, R.; Miyabe, M.; Tamura, T.

10.1101/2024.03.11.584350 — cell biology — Posted on 2024-03-12

3433 The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi

Weyer, Y.; Schwabl, S. I.; Tang, X.; Widerin, M. A.; Niedrist, V.; Tettamanti, M. G.; Weys, S.; Sarg, B.; Kremser, L.; Liedl, K. R.; Schmidt, O.; Teis, D.

10.1101/2024.03.11.584465 — cell biology — Posted on 2024-03-12

3434 Click-free imaging of carbohydrate trafficking in live cells using an azido photothermal probe

Xia, Q.; Perera, H. A.; Bolarinho, R.; Piskulich, Z. A.; Guo, Z.; Yin, J.; He, H.; Li, M.; Ge, X.; Cui, Q.; Ramstrom, O.; Yan, M.; Cheng, J.-X.

10.1101/2024.03.08.584185 — cell biology — Posted on 2024-03-12

3435 Development of alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell derived liver organoids

Feng, Z.; Zhou, B.; Shuai, Q.; Wei, Y.; Jin, N.; Wang, X.; Zhao, H.; Liu, Z.; Xu, J.; Mu, J.; Xie, J.

10.1101/2024.03.10.584291 — cell biology — Posted on 2024-03-12

3436 High-throughput Screening of Compounds against Autoluminescent Nonreplicating Mycobacterium tuberculosis under Diverse Conditions

Tian, X.; Ma, W.; Yusuf, B.; Li, C.; Hameed, H. M. A.; Wang, X.; Zhong, N.; Hu, J.; Zhang, T.

10.1101/2024.03.10.584296 — microbiology — Posted on 2024-03-12

3437 Establishment of an Inhalation Administration Noninvasive Murine Model for Rapidly Testing Drug Activity against Mycobacterium tuberculosis

Tian, X.; Gao, Y.; Ma, W.; Zhang, J.; Ju, Y.; Ding, J.; Zeng, S.; Hameed, A.; Zhong, N.; Cook, G. M.; Hu, J.; zhang, T.

10.1101/2024.02.27.582260 — microbiology — Posted on 2024-03-12

3438 On the Evolution of Chromosomal Regions with High Gene Strand Bias in Bacteria

Tomasch, J.; Kopejtka, K.; Shivaramu, S.; Mujakic, I.; Koblizek, M.

10.1101/2024.02.28.582576 — microbiology — Posted on 2024-03-12

3439 Mean exercise torque is a critical factor influencing neuromuscular fatigability induced by exhausting contractions

Lebesque, L.; Scaglioni, G.; Manckoundia, P.; Martin, A.

10.1101/2024.03.06.583664 — physiology — Posted on 2024-03-12

3440 Stochastic Voronoi Tessellations as Models for Cellular Neighborhoods in Simple Multicellular Organisms

Srinivasan, A.; Hohn, S. S. M. H.; Goldstein, R. E.

10.1101/2024.03.11.584390 — biophysics — Posted on 2024-03-12

3441 Uncovering the BIN1-SH3 interactome underpinning centronuclear myopathy

Zambo, B.; Edelweiss, E.; Morlet, B.; Negroni, L.; Pajkos, M.; Dosztanyi, Z.; Ostergaard, S.; Trave, G.; Laporte, J.; Gogl, G.

10.1101/2023.02.14.528471 — biochemistry — Posted on 2024-03-12

3442 Microtubule poleward flux as a target for modifying chromosome segregation errors

Risteski, P.; Martincic, J.; Tintor, E.; Jagric, M.; Tolic, I. M.

10.1101/2024.03.11.584498 — cell biology — Posted on 2024-03-12

3443 Targeted protein degradation of the CPSF complex by benzoxaboroles through sumoylation

Zhang, N.; Samad, A.; Zahedifard, F.; Wall, R. J.; Horn, D.; Zoltner, M.; Field, M. C.

10.1101/2024.03.11.584402 — cell biology — Posted on 2024-03-12

3444 Non-endothelial expression of Endomucin in the mouse and human choroid

Brookins, E.; Serrano, S. E.; Yacu, G. S.; Finer, G.; Thomson, B. R.

10.1101/2024.03.08.584133 — cell biology — Posted on 2024-03-12

3445 A Microphysiological HHT-on-a-Chip Platform Recapitulates Patient Vascular Lesions

Fang, J.; Hatch, C. J.; Andrejecsk, J.; Van Trigt, W.; Juat, D. J.; Chen, Y.-H.; Matsumoto, S.; Lee, A. P.; Hughes, C. C.

10.1101/2024.03.11.584490 — cell biology — Posted on 2024-03-12

3446 Distinct intersecting pathways link homolog pairing to initiation of meiotic chromosome synapsis

Blazickova, J.; Trivedi, S.; Bowman, R.; Geetha, S. S.; Subah, S.; Smolikove, S.; Jantsch, V.; Zetka, M.; Silva, N.

10.1101/2024.03.11.584447 — cell biology — Posted on 2024-03-12

3447 A perivascular niche supports endometrial epithelial regeneration

Li, S.-Y.; Whiteside, S.; Li, B.; Sun, X.; DeFalco, T.

10.1101/2024.03.07.583958 — cell biology — Posted on 2024-03-12

3448 Spatial targeting of the prostaglandin receptor EP2 to very early endosomes co-ordinates PGE2-mediated cAMP signaling in decidualizing human endometrium

Brighton, P. J.; Walker, A. R.; Mann, O.; Kong, C.-S.; Lucas, E. S.; Vrljicak, P.; Brosens, J. J.; Hanyaloglu, A. C.

10.1101/2024.03.07.582712 — cell biology — Posted on 2024-03-12

3449 A cellular assay to determine the fusion capacity of MFN2 variants linked to Charcot-Marie-Tooth type 2A

Barsa, C.; Perrin, J.; David, C.; Mourier, A.; Rojo, M.

10.1101/2024.03.11.584414 — cell biology — Posted on 2024-03-12

3450 Fertilization-induced synergid cell death by RALF12-triggered ROS production and ethylene signaling

Chen, J.; Wang, H.; Wang, J.; Qu, W.; Zheng, X.; Fang, H.; Wang, S.; He, L.; Hao, S.; Dresselhaus, T.

10.1101/2024.03.10.584218 — cell biology — Posted on 2024-03-12

3451 Direct Relationship between Protein Expression and Progeny Yield of Herpes Simplex Virus 1 Unveils a Rate-limiting Step for Virus Production

Nobe, M.; Maruzuru, Y.; Takeshima, K.; Maeda, F.; Kusano, H.; Yoshimura, R.; Nishiyama, T.; Park, H.; Kozaki, Y.; Iwami, S.; Koyanagi, N.; Kato, A.; Natsume, T.; Adachi, S.; Kawaguchi, Y.

10.1101/2023.06.07.544155 — microbiology — Posted on 2024-03-12

3452 Nutrient colimitation is a quantitative, dynamic property of microbial populations

Held, N. A.; Krishna, A.; Crippa, D.; Dragan, A.; Manhart, M.

10.1101/2023.09.27.559472 — microbiology — Posted on 2024-03-12

3453 Whole-Brain Causal Discovery Using fMRI

Arab, F.; Ghassami, A.; Jamalabadai, H.; Peters, M. A. K.; Nozari, E.

10.1101/2023.08.12.553067 — neuroscience — Posted on 2024-03-12

3454 Prior probability cues bias sensory encoding with increasing task exposure

Walsh, K.; McGovern, D. P.; Dully, J.; Kelly, S. P.; O'Connell, R. G.

10.1101/2023.07.15.549123 — neuroscience — Posted on 2024-03-12

3455 The functional anatomy of nociception: effective connectivity in chronic pain and placebo responders

Nara, S.; Baliki, M.; Friston, K.; Ray, D.

10.1101/2024.03.10.584304 — neuroscience — Posted on 2024-03-12

3456 Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells

10.1101/2023.04.21.537849 — cancer biology — Posted on 2024-03-12

3457 Elephant rumble vocalizations: spectral substructures and superstructures

Rantsiou, E.

10.1101/2024.03.10.584305 — animal behavior and cognition — Posted on 2024-03-12

3458 Ecosystem Links: Macrophytes, Snail Preferences, and Trematode Transmission in Man-Made Water Bodies

Mudavanhu, A.; Goossens, E.; Schols, R.; Manyangadze, T.

10.1101/2024.02.29.582719 — ecology — Posted on 2024-03-12

3459 The P600 during sentence reading predicts behavioral and neural markers of recognition memory

Contier, F.; Hoeger, M.; Rabovsky, M.

10.1101/2024.03.08.584041 — neuroscience — Posted on 2024-03-12

3460 Estradiol and Flutamide Effects on the Song System of Developing Male Zebra Finches

Grisham, W.; McCormick, M. E.

10.1101/2024.03.11.584474 — neuroscience — Posted on 2024-03-12

3461 Layer 5 Martinotti cell activation reduces pyramidal cell population plasticity and improves fine motor function

Velica, A.; Malfatti, T.; Winne, J.; Ciralli, B.; Henriksson, K.; Nogueira, I.; Asimakidou, E.; Nascimento, G.; Leao, R.; Kullander, K.

10.1101/2024.03.10.584276 — neuroscience — Posted on 2024-03-12

3462 A shifting role of thalamocortical connectivity in the emergence of large-scale functional brain organization across early lifespan development

Park, S.; Haak, K. V.; Oldham, S.; Cho, H.; Byeon, K.; Park, B.-y.; Thomson, P.; Chen, H.; Gao, W.; Xu, T.; Valk, S. L.; Milham, M.; Bernhardt, B.; Di Martino, A.; Hong, S.-J.

10.1101/2024.03.11.584415 — neuroscience — Posted on 2024-03-12

3463 Dorsal hippocampus represents locations to avoid as well as locations to approach during approach-avoidance conflict

Calvin, O. L.; Erickson, M. T.; Walters, C. J.; Redish, A. D.

10.1101/2024.03.10.584295 — neuroscience — Posted on 2024-03-12

3464 Monkeys have rhythnm

Rajendran, V. G.; Marquez, J. P.; Prado, L.; Merchant, H.

10.1101/2024.03.11.584468 — neuroscience — Posted on 2024-03-12

3465 Cell extrusion - a novel mechanism driving neural crest cell delamination

Moore, E. L.; Zhao, R.; McKinney, M. C.; Yi, K.; Wood, C. L.; Trainor, P.

10.1101/2024.03.09.584232 — developmental biology — Posted on 2024-03-12

3466 Polyglutamylation of microtubules drives neuronal remodeling

Gavoci, A.; Zhiti, A.; Ruskov, M.; Magiera, M. M.; Wang, M.; Ziegler, K. A.; Hausrat, T. J.; Engelhardt, S.; Kneussel, M.; Balastik, M.; Janke, C.; Misgeld, T.; Brill, M. S.

10.1101/2024.03.11.584412 — cell biology — Posted on 2024-03-12

3467 MULTIMODAL GRADIENTS UNIFY LOCAL AND GLOBAL CORTICAL ORGANIZATION

Wang, Y.; Eichert, N.; Paquola, C.; Rodriguez-Cruces, R.; DeKraker, J.; Royer, J.; Cabalo, D. G.; Auer, H.; Ngo, A.; Leppert, I.; Tardif, C. L.; Rudko, D. A.; Amunts, K.; Smallwood, J.; Evans, A. C.; Bernhardt, B. C.

10.1101/2024.03.11.583969 — neuroscience — Posted on 2024-03-12

3468 The gamma-butyrolactone receptors ScbR and AtrA form a quorum sensing switch between coelimycin and actinorhodin synthesis in Streptomyces coelicolor A3(2)

Bednarz, B.; Kotowska, M.; Wenecki, M.; Derkacz, M.; Jastrzemska, A.; Ciekot, J.; Pawlik, K. J.

10.1101/2024.03.11.584493 — molecular biology — Posted on 2024-03-11

3469 Distinct Patterns of SARS-CoV-2 BA.2.87.1 and JN.1 Variants in Immune Evasion, Antigenicity and Cell-Cell Fusion

Li, P.; Liu, Y.; Faraone, J.; Hsu, C. C.; Chamblee, M.; Zheng, Y.-M.; Carlin, C.; Bednash, J. S.; Horowitz, J. C.; Mallampalli, R. K.; Saif, L. J.; Oltz, E. M.; Jones, D.; Li, J.; Gumina, R. J.; Liu, S.-L.

10.1101/2024.03.11.583978 — microbiology — Posted on 2024-03-11

3470 Exploring the therapeutic potential of defective interfering particles in reducing the replication of SARS-CoV-2

Locke, M.; Grebennikov, D.; Sazonov, I.; Lopez-Garcia, M.; Loguinova, M.; Meyerhan, A.; Bocharov, G.; Molina-Paris, C.

10.1101/2024.03.11.584367 — microbiology — Posted on 2024-03-11

3471 Disentangling the potential factors defining Bacillus subtilis abundance in natural soils

Xu, X.; Pioppi, A.; Kiesewalter, H. T.; Strube, M. L.; Kovacs, A. T.

10.1101/2024.03.11.584434 — microbiology — Posted on 2024-03-11

3472 gcplyr: an R package for microbial growth curve data analysis

Blazanin, M.

10.1101/2023.04.30.538883 — microbiology — Posted on 2024-03-11

3473 Combinatorial control of type IVa pili formation by the four polarized regulators MglA, SgmX, FrzS and SopA

Oklitschek, M.; Carreira, L. A. M.; Muratoglu, M.; Sogaard-Andersen, L.; Treuner-Lange, A.

10.1101/2024.03.11.584430 — microbiology — Posted on 2024-03-11

3474 Staphylococcus aureus Persistence in Osteocytes: Weathering the Storm of Antibiotics and Autophagy/Xenophagy

Gunn, N. J.; Zelmer, A. R.; Kidd, S. P.; Solomon, L. B.; Yang, D.; Roscioli, E.; Atkins, G. J.

10.1101/2023.10.27.564475 — microbiology — Posted on 2024-03-11

3475 A continuum of CD4+ T cell 'help' defines 1 Memory B cell fate

Pritchard, G. H.; Krishnamurty, A. T.; Rodda, L.; McDougal, C.; Shehata, L.; Pepper, M.

10.1101/564351 — immunology — Posted on 2024-03-11

3476 Genetic load, eco-evolutionary feedback and extinction in metapopulations

Olusanya, O.; Khudiakova, K. A.; Sachdeva, H.

10.1101/2023.12.02.569702 — evolutionary biology — Posted on 2024-03-11

3477 A method for estimating dynamic functional network connectivity gradients (dFNG) from ICA captures smooth inter-network modulation.

Soleimani, N.; Iraji, A.; Belger, A.; Calhoun, V.

10.1101/2024.03.06.583731 — neuroscience — Posted on 2024-03-11

3478 High Frequency Terahertz Stimulation Alleviates Neuropathic Pain by Inhibiting the Pyramidal Neuron Activity in the Anterior Cingulate Cortex of mice

Peng, W.; Wang, P.; Tan, C.; Zhao, H.; Chen, K.; Si, H.; Tian, Y.; Lou, A.; Zhu, Z.; Yuan, Y.; Wu, K.; Chang, C.; Wu, Y.; Chen, T.

10.1101/2024.03.06.583763 — neuroscience — Posted on 2024-03-11

3479 Sleep need driven oscillation of glutamatergic synaptic phenotype

Vogt, K.; Kulkarni, A.; Pandey, R.; Dehnad, M.; Konopka, G.; Greene, R. W.

10.1101/2024.02.05.578985 — neuroscience — Posted on 2024-03-11

3480 Network connectivity differences between perceptual and emotional music listening

Faber, S. E.; McIntosh, A. R.; Brown, T.; Carpentier, S.

10.1101/2023.07.05.547865 — neuroscience — Posted on 2024-03-11

3481 A multidimensional investigation of sleep and biopsychosocial profiles with associated neural signatures

Perrault, A. A.; Kebets, V.; Kuek, N. M. Y.; Cross, N. E.; Tesfaye, R.; Pomares, F. B.; Li, J.; Chee, M. W. L.; Dang Vu, T. T.; Yeo, B. T. T.

10.1101/2024.02.15.580583 — neuroscience — Posted on 2024-03-11

3482 Distributed network flows generate localized category selectivity in human visual cortex

Cocuzza, C. V.; Sanchez-Romero, R.; Ito, T.; Mill, R. D.; Keane, B. P.; Cole, M. W.

10.1101/2022.02.19.481103 — neuroscience — Posted on 2024-03-11

3483 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations

Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.

10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-11

3484 How distinct sources of nuisance variability in natural images and scenes limit human stereopsis

White, D. N.; Burge, J.

10.1101/2024.02.27.582383 — neuroscience — Posted on 2024-03-11

3485 The Drosophila Circadian Clock Gene Cycle Controls Development of Clock Neurons

Biondi, G.; McCormick, G. M.; Fernandez, M. P.

10.1101/2023.10.29.564626 — neuroscience — Posted on 2024-03-11

3486 Chronic alcohol induces subcircuit-specific striatonigral plasticity enhancing the sensorimotor basal ganglia role in action execution

Sitzia, G.; Bariselli, S.; Gracias, A.; Lovinger, D. M.

10.1101/2023.11.15.567225 — neuroscience — Posted on 2024-03-11

3487 Cell-cycle and Age-Related Modulations in Mouse Chromosome Stiffness

Liu, N.; Qiang, W.; Jordan, P.; Marko, J. F.; Qiao, H.

10.1101/2024.03.06.583771 — biophysics — Posted on 2024-03-11

3488 Unlocking the Potential of High-Quality Dopamine Transporter Pharmacological Data: Advancing Robust Machine Learning-Based QSAR Modeling

Lee, K. H.; Won, S. J.; Oyinloye, P.; Shi, L.

10.1101/2024.03.06.583803 — bioinformatics — Posted on 2024-03-11

3489 genomalicious: serving up a smorgasbord of R functions for performing and teaching population genomic analyses

Thia, J. A.

10.1101/667337 — bioinformatics — Posted on 2024-03-11

3490 Integrative Co-Registration of Elemental Imag-ing and Histopathology for Enhanced Spatial Multimodal Analysis of Tissue Sections through TRACE

Lu, Y.; Steiner, R.; Han, S.; Srivastava, A.; Shaik, N.; Chan, M.; Diallo, A.; Punshon, T.; Jackson, B.; Kolling, F.; Vahdat, L.; Vaickus, L.; Marotti, J.; Ho, S.; Levy, J.

10.1101/2024.03.06.583819 — bioinformatics — Posted on 2024-03-11

3491 Motor Hotspot Localization Based on Electroencephalography Using Convolutional Neural Network in Patients with Stroke

Choi, G.-Y.; Seo, J.-K.; Kim, K. T.; Chang, W. K.; Paik, N.-J.; Kim, W.-S.; Hwang, H.-J.

10.1101/2024.03.06.583618 — bioengineering — Posted on 2024-03-11

3492 Structural and biophysical characterisation of ubiquitin variants that specifically inhibit the ubiquitin conjugating enzyme Ube2d2

McAlpine, J. M.; Zhu, J.; Pudjihartono, N.; Teyra, J.; Currie, M. J.; Dobson, R. C.; Sidhu, S. S.; Day, C. L.; Middleton, A. J.

10.1101/2024.03.10.583603 — biochemistry — Posted on 2024-03-11

3493 Human primosome requires replication protein A when copying DNA with inverted repeats

Baranovskiy, A.; Morstadt, L.; Babayeva, N.; Tahirov, T. H.

10.1101/2024.03.11.584335 — biochemistry — Posted on 2024-03-11

3494 Stochastic characterization of navigation strategies in an automated variant of the Barnes maze

Lee, J.-Y.; Jung, D.; Royer, S.

10.1101/2023.04.14.536859 — animal behavior and cognition — Posted on 2024-03-11

3495 MegaLMM improves genomic predictions in new environments using environmental covariates

Hu, H.; Rincent, R.; Runcie, D. E.

10.1101/2024.03.06.583749 — genetics — Posted on 2024-03-11

3496 A change in cis-regulatory logic underlying obligate versus facultative muscle multinucleation in chordates

Johnson, C. J.; Zhang, Z.; Zhang, H.; Shang, R.; Piekarz, K. M.; Bi, P.; Stolfi, A.

10.1101/2024.03.06.583753 — evolutionary biology — Posted on 2024-03-11

3497 Microbial Response to Natural Disturbances: Rare Biosphere often plays a role

Zhao, J.; Brandt, G.; Wang, Z.; Hunt, D. E.; Rodriguez-R, L. M.; Hatt, J. K.; Konstantinidis, K. T.

10.1101/2024.03.06.583742 — ecology — Posted on 2024-03-11

3498 Deletion of RFX6, a Diabetes-Associated Gene, Impairs iPSC-Derived Islet Organoid Development and Survival, With No Impact on the Generation of PDX1+/NKX6.1+ Progenitors

Aldous, N.; Elsayed, A. K.; Memon, B.; Ijaz, S.; Hayat, S.; Abdelalim, E. M.

10.1101/2024.03.06.583663 — developmental biology — Posted on 2024-03-11

3499 The RNA demethylases ALKBH5 and FTO regulate translation of the ATF4 mRNA in sorafenib-treated hepatocarcinoma cells

Mazroui, R.; Adjibade, P.

10.1101/2024.02.09.577647 — cancer biology — Posted on 2024-03-11

3500 Identifying Reproducible Transcription Regulator Coexpression Patterns with Single Cell Transcriptomics

Morin, A.; Chu, C.; Pavlidis, P.

10.1101/2024.02.15.580581 — bioinformatics — Posted on 2024-03-11

3501 RNA3DB: a structurally-dissimilar dataset split for training and benchmarking deep learning models for RNA structure prediction

Szikszai, M.; Magnus, M.; Sanghi, S.; Kadyan, S.; Bouatta, N.; Rivas, E.

10.1101/2024.01.30.578025 — bioinformatics — Posted on 2024-03-11

3502 Molecular basis of proteolytic cleavage regulation by the extracellular matrix receptor dystroglycan

Anderson, M. J.; Hayward, A. N.; Smiley, A. T.; Shi, K.; Pawlak, M. R.; Aird, E. J.; Grant, E.; Greenberg, L.; Aihara, H.; Ulens, C.; Evans, R. L.; Gordon, W. R.

10.1101/2022.04.04.487063 — biochemistry — Posted on 2024-03-11

3503 EpicTope: narrating protein sequence features to identify non-disruptive epitope tagging sites

Zinski, J.; Chung, H.; Joshi, P.; Warrick, F.; Berg, B. D.; Glova, G.; McGrail, M. A.; Balciunas, D.; Friedberg, I.; Mullins, M. C.

10.1101/2024.03.03.583232 — developmental biology — Posted on 2024-03-11

3504 Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells

Balestrini, P. A.; Abdelbaki, A.; McCarthy, A.; Devito, L.; Senner, C. E.; Chen, A. E.; Munusamy, P.; Blakeley, P.; Elder, K.; Snell, P.; Christie, L.; Serhal, P.; Odia, R. A.; Sangrithi, M.; Niakan, K. K.; Fogarty, N. M.

10.1101/2021.08.18.456785 — developmental biology — Posted on 2024-03-11

3505 Unexpected roles for AMPK in the suppression of autophagy and the reactivation of mTORC1 signaling during prolonged amino acid deprivation

Kazyken, D.; Dame, S. G.; Wang, C.; Wadley, M.; Fingar, D. C.

10.1101/2023.12.20.572593 — cell biology — Posted on 2024-03-11

3506 YmoA functions as a molecular stress sensor in Yersinia

Hechard, T.; Lu, L.; Edgren, T.; Chi, C.; Wang, H.

10.1101/2024.03.11.584355 — molecular biology — Posted on 2024-03-11

3507 Sacbrood viruses and select Lake Sinai virus variants dominated Apis mellifera colonies symptomatic for European foulbrood

Hesketh-Best, P. J.; Fowler, P. D.; Odogwu, N. M.; Milbrath, M. O.; Schroeder, D. C.

10.1101/2024.03.11.584375 — molecular biology — Posted on 2024-03-11

3508 Mycobacterium tuberculosis FtsB and PerM interact via a C-terminal helix in FtsB to modulate cell division

Hensel, Z.; Xu, R.; Ferreira, J. R.

10.1101/2024.03.11.584518 — molecular biology — Posted on 2024-03-11

3509 Multiple levels of transcriptional regulation control glycolate metabolism in Paracoccus denitrificans

Schada von Borzyskowski, L.; Hermann, L.; Kremer, K.; Barthel, S.; Pommerenke, B.; Glatter, T.; Paczia, N.; Bremer, E.; Erb, T. J.

10.1101/2024.03.11.584432 — microbiology — Posted on 2024-03-11

3510 Protection from plague via single dose administration of antibody to neutralize the type I interferon response

Marks, K. D.; Anderson, D. M.

10.1101/2024.03.11.584497 — microbiology — Posted on 2024-03-11

3511 Helicobacter pylori gamma-glutamyltransferase relates to proteomic adaptions important for gastric colonization

Fuchs, S.; Fiedler, M. K.; Heiduk, N.; Wanisch, A.; Debowski, A. W.; Marshall, B. J.; Sieber, S. A.; Gerhard, M.; Mejias-Luque, R.

10.1101/2024.03.11.584369 — microbiology — Posted on 2024-03-11

3512 FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria

Halte, M.; Andrianova, E. P.; Goosmann, C.; Chevance, F. F. V.; Hughes, K. T.; Zhulin, I. B.; Erhardt, M.

10.1101/2024.03.11.584431 — microbiology — Posted on 2024-03-11

3513 Human mobility and malaria risk in peri-urban and rural communities in the Peruvian Amazon

Gomez, J.; Grosso, A.; Guzman-Guzman, M.; Garcia Castillo, S.; Castro, M. C.; Torres, K.; Vinetz, J. M.; Gamboa, D.

10.1101/2024.03.11.584373 — microbiology — Posted on 2024-03-11

3514 Epidemiological inference at the threshold of data availability: an influenza A(H1N2)v spillover event in the United Kingdom

Fozard, J. A.; Thomson, E. C.; Illingworth, C.

10.1101/2024.03.11.584378 — microbiology — Posted on 2024-03-11

3515 Pre-trained molecular representations enable antimicrobial discovery

Olayo-Alarcon, R.; Amstalden, M. K.; Zannoni, A.; Bajramovic, M.; Sharma, C. M.; Brochado, A. R.; Rezaei, M.; Müller, C. L.

10.1101/2024.03.11.584456 — microbiology — Posted on 2024-03-11

3516 High-resolution analysis of the treated coeliac disease microbiome reveals increased inter-individual variability

Slager, J.; Simpson, H. L.; Gacesa, R.; Chen, L.; Gelderloos, J.; Maatman, A.; Wijmenga, C.; Zhernakova, A.; Fu, J.; Weersma, R.; Gonera, G.; Jonkers, I. H.; Withoff, S.

10.1101/2024.03.08.584098 — microbiology — Posted on 2024-03-11

3517 A low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics

King, E. S.; Stacey, A. E.; Scott, J. G.

10.1101/2024.03.08.584154 — microbiology — Posted on 2024-03-11

3518 Functional Mapping of Movement and Speech Using Task-Based Electrophysiological Changes in Stereoelectroencephalography

Jensen, M. A.; Fine, A.; Kerezoudis, P.; Wong-Kisiel, L.; Alden, E.; Hermes, D.; Miller, K. J.

10.1101/2024.02.29.582865 — neuroscience — Posted on 2024-03-11

3519 Synaptic connectome of the Drosophila circadian clock

Reinhard, N.; Fukuda, A.; Manoli, G.; Derksen, E.; Saito, A.; Möller, G.; Sekiguchi, M.; Rieger, D.; Helfrich-Förster, C.; Yoshii, T.; Zandawala, M.

10.1101/2023.09.11.557222 — neuroscience — Posted on 2024-03-11

3520 TRPC6 is a mechanosensitive channel essential for ultrasound neuromodulation in mammalian brain

Matsushita, Y. M.; Yoshida, K.; Yoshiya, M.; Shimizu, T.; Tsukamoto, S.; Takeuchi, Y.; Higuchi, M.; Shimojo, M.

10.1101/2024.03.06.583779 — neuroscience — Posted on 2024-03-11

3521 Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation

Marin, E. C.; Morris, B. J.; Stuerner, T.; Champion, A. S.; Krzeminski, D.; Badalamente, G.; Gkantia, M.; Dunne, C. R.; Eichler, K.; Takemura, S.-y.; Tamimi, I. F. M.; Fang, S.; Moon, S. S.; Cheong, H. S. J.; Li, F.; Schlegel, P.; Ahnert, S. E.; Berg, S.; FlyEM Project Team, ; Card, G. M.; Costa, M.; Shepherd, D.; Jefferis, G. S. X. E.

10.1101/2023.06.05.543407 — neuroscience — Posted on 2024-03-11

3522 Periaqueductal gray activates antipredatory neural responses in the amygdala of foraging rats

Kim, E. J.; Kong, M.-S.; Park, S.; Cho, J.; Kim, J. J.

10.1101/2023.05.19.541463 — neuroscience — Posted on 2024-03-11

3523 Biodiversity is enhanced by sequential resource utilization and environmental fluctuations via emergent temporal niches

Bloxham, B.; Lee, H.; Gore, J.

10.1101/2023.02.17.529002 — systems biology — Posted on 2024-03-11

3524 Hypothalamic hormone deficiency enables physiological anorexia

Mohr, S. M.; Pra, R. D.; Platt, M. P.; Feketa, V. V.; Shanabrough, M.; Varela, L.; Kristant, A.; Cao, H.; Merriman, D. K.; Horvath, T. L.; Bagriantsev, S. N.; Gracheva, E. O.

10.1101/2023.03.15.532843 — physiology — Posted on 2024-03-11

3525 Application of mechanistic multiparameter optimization and large scale in vitro to in vivo pharmacokinetics correlations to small molecule therapeutic projects

Broccatelli, F.; Veeravalli, V.; Cashion, D.; Baylon, J. L.; Lombardo, F.; Jia, L.

10.1101/2024.03.06.583780 — pharmacology and toxicology — Posted on 2024-03-11

3526 Glutamine addiction is targetable via altering splicing of nutrient sensors and epitranscriptome regulators

Bojko, J.; Kollareddy, M.; Szemes, M.; Bellamy, J.; Poon, E.; Moukachar, A.; Legge, D.; Vincent, E. E.; Jones, N.; Malik, S.; Greenhough, A.; Paterson, A.; Park, J. H.; Gallacher, K.; Chesler, L.; Malik, K.

10.1101/2024.02.28.582087 — cancer biology — Posted on 2024-03-11

3527 Functional multi-omics reveals genetic and pharmacologic regulation of surface CD38 in multiple myeloma

Choudhry, P.; Kasap, C.; Patino Escobar, B.; Gugliemini, O.; Geng, H.; Sarin, V.; Kang, A.; Kishishita, A.; Rampersaud, S.; Sarah, L.; Lin, Y.-H. T.; Paranjape, N.; Ramkumar, P.; Marcoulis, M.; Wang, D.; Phojanakong, P.; Steri, V.; Hann, B.; Kampmann, M.; Wiita, A.

10.1101/2021.08.04.455165 — cancer biology — Posted on 2024-03-11

3528 SIGNAL-seq: Multimodal Single-cell Inter- and Intra-cellular Signalling Analysis

Opzoomer, J. W.; O'Sullivan, R.; Sufi, J.; Madsen, R. R.; Qin, X.; Basiarz, E.; Tape, C. J.

10.1101/2024.02.23.581433 — cancer biology — Posted on 2024-03-11

3529 Improving generalizability for MHC-I binding peptide predictions through geometric deep learning

Marzella, D. F.; Crocioni, G.; Radusinovic, T.; Lepikhov, D.; Severin, H.; Bodor, D. L.; Rademaker, D. T.; Lin, C.; Georgievska, S.; Renaud, N.; Kessler, A. L.; Lopez-Tarifa, P.; Buschow, S.; Bekkers, E.; Xue, L. C.

10.1101/2023.12.04.569776 — bioinformatics — Posted on 2024-03-11

3530 Towards Generative RNA Design With Tertiary Interactions

Patil, S.; Runge, F.; Franke, J. K. H.; Hutter, F.

10.1101/2024.03.09.584209 — bioinformatics — Posted on 2024-03-11

3531 Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models

LI, W.; Jiang, X.; Wang, W.; Hou, L.; Cai, R.; Li, Y.; Gu, Q.; Chuai, G.; Chen, Q.; Ma, P.; Tang, J.; Guo, M.; Huang, X.; Zhang, J.; Liu, Q.

10.1101/2024.03.11.583506 — bioinformatics — Posted on 2024-03-11

3532 PseudoCell: A Multi-Valued Logical Regulatory Network to Investigate Premature Senescence Dynamics and Heterogeneity

Pierdona, V.; Lavandoski, P.; Maurmann, R. M.; Borges, G. A.; Mombach, J. C. M.; Guma, F. T. C. R.; Barbe-Tuana, F. M.

10.1101/2023.07.20.549793 — bioinformatics — Posted on 2024-03-11

3533 Structural basis of substrate transport and drug recognition by the human thiamine transporter SLC19A3

Gabriel, F.; Spriestersbach, L.; Fuhrmann, A.; Jungnickel, K. E. J.; Mostafavi, S.; Pardon, E.; Steyaert, J.; Loew, C.

10.1101/2024.03.11.584396 — biochemistry — Posted on 2024-03-11

3534 Revisiting Y-chromosome detection methods: R-CQ and KAMY efficiently identify Y chromosome sequences in Tephritidae insect pests

Rallis, D.; Tsoumani, K. T.; Krsticevic, F.; Papathanos, P. A.; Mathiopoulos, K. D.; Papanicolaou, A.

10.1101/2023.10.27.564325 — genomics — Posted on 2024-03-11

3535 Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations

Izutsu, M.; Lake, D. M.; Matson, Z. W. D.; Dodson, J. P.; Lenski, R. E.

10.1101/2021.12.29.474457 — evolutionary biology — Posted on 2024-03-11

3536 Connecting species-specific extents of genome reduction in mitochondria and plastids

Giannakis, K.; Richards, L.; Dauda, K.; Johnston, I.

10.1101/2023.12.14.571654 — evolutionary biology — Posted on 2024-03-11

3537 Frequency-dependent ecological interactions increase the prevalence and shape the distribution of pre-existing drug resistance

Maltas, J.; Tadele, D. S.; Durmaz, A.; McFarland, C. D.; Hinczewski, M.; Scott, J. G.

10.1101/2023.03.16.533001 — evolutionary biology — Posted on 2024-03-11

3538 Analysis of the Leishmania mexicana promastigote cell cycle using imaging flow cytometry provides new insights into cell cycle flexibility and events of short duration.

Howell, J.; Omwenga, S.; Jimenez, M.; Hammarton, T. C.

10.1101/2023.07.24.550259 — cell biology — Posted on 2024-03-11

3539 Haplo-insufficiency of Profilin1 in vascular endothelial cells is beneficial but not sufficient to confer protection against experimentally induced atherosclerosis

Allen-Gondringer, A.; Gau, D.; Dutta, P.; Roy, P.

10.1101/2023.12.06.570450 — cell biology — Posted on 2024-03-11

3540 An EpCAM/Trop2 mechanostat differentially regulates individual and collective behaviour of human carcinoma cells

Aslemarz, A.; Fagotto-Kaufmann, M.; Ruppel, A.; Fagotto-Kaufmann, C.; Balland, M.; Lasko, P.; Fagotto, F.

10.1101/2022.10.03.510449 — cell biology — Posted on 2024-03-11

3541 Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes

Farrell, K.; Wang, J. T.; Stearns, T.

10.1101/2022.11.08.515699 — cell biology — Posted on 2024-03-11

3542 P66Shc Mediates SUMO2-induced Endothelial Dysfunction

Kumar, J.; Uppulapu, s. K.; Kumari, S.; Sharma, K.; Paradee, W. J.; Yadav, R. P.; Kumar, V.; Kumar, S.

10.1101/2024.01.24.577109 — cell biology — Posted on 2024-03-11

3543 Nucleomorph phylogenomics suggests a deep and ancient origin of cryptophyte plastids within Rhodophyta

Novak, L. V. F.; Munoz-Gomez, S. A.; van Beveren, F.; Ciobanu, M.; Eme, L.; Lopez-Garcia, P.; Moreira, D.

10.1101/2024.03.10.584144 — microbiology — Posted on 2024-03-11

3544 SARS-CoV-2 Omicron BA.2.87.1 Exhibits Higher Susceptibility to Serum Neutralization Than EG.5.1 and JN.1

Wang, Q.; Guo, Y.; Schwanz, L. T.; Mellis, I. A.; Sun, Y.; Qu, Y.; Urtecho, G.; Valdez, R.; Stoneman, E.; Gordon, A.; Wang, H. H.; Liu, L.; Ho, D. D.

10.1101/2024.03.10.584306 — microbiology — Posted on 2024-03-11

3545 Variant mutation in SARS-CoV-2 nucleocapsid enhances viral infection via altered genomic encapsidation

Kubinski, H. C.; Despres, H. W.; Johnson, B. A.; Schmidt, M. M.; Jaffrani, S. A.; Mills, M. G.; Lokugamage, K.; Dumas, C. M.; Shirley, D. J.; Estes, L. K.; Pekosz, A.; Crothers, J. W.; Roychoudhury, P.; Greninger, A. L.; Jerome, K. R.; Martorelli Di Genova, B.; Walker, D. H.; Ballif, B. A.; Ladinsky, M. S.; Bjorkman, P. J.; Menachery, V. D.; Bruce, E. A.

10.1101/2024.03.08.584120 — microbiology — Posted on 2024-03-11

3546 Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis

Secli, V.; Michetti, E.; Pacello, F.; Iacovelli, F.; Falconi, M.; Astolfi, M. L.; Visaggio, D.; Visca, P.; Ammendola, S.; Battistoni, A.

10.1101/2024.01.07.574578 — microbiology — Posted on 2024-03-11

3547 The antigenic landscape of human influenza N2 neuraminidases from 2009 until 2017

Catani, J. P.; Smet, A.; Ysenbaert, T.; Vuylsteke, M.; Bottu, G.; Mathys, J.; Botzki, A.; Cortes-Garcia, G.; Strudnell, T.; Gomila, R.; Hamberger, J.; Catalan, J.; Ustyugova, I.; Farrell, T.; Stegalkina, S.; Ray, S.; LaRue, L.; Saelens, X.; Vogel, T. U.

10.1101/2023.08.30.555500 — immunology — Posted on 2024-03-11

3548 Non-uniform contextual interactions in the visual cortex place fundamental limits on spatial vision

Morton, M. P.; Denagamage, S.; Hudson, N. V.; Nandy, A. S.

10.1101/2023.08.15.553380 — neuroscience — Posted on 2024-03-11

3549 Developmental pyrethroid exposure disrupts molecular pathways for MAP kinase and circadian rhythms in mouse brain

Nguyen, J. H.; Curtis, M. A.; Imami, A. S.; Ryan, W. G.; Alganem, K.; Neifer, K. L.; Saferin, N.; Nawor, C. N.; Kistler, B. P.; Miller, G. W.; Shukla, R.; McCullumsmith, R. E.; Burkett, J. P.

10.1101/2023.08.28.555113 — neuroscience — Posted on 2024-03-11

3550 Morphology, but not microtubules, of the retinal nerve fibers are protected by nicotinamide in glaucoma mice

Boodram, V.; Lim, H.

10.1101/2024.03.07.583928 — neuroscience — Posted on 2024-03-11

3551 Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy

Rhymes, E. R.; Simkin, R. L.; Qu, J.; Villarroel-Campos, D.; Surana, S. N.; Tong, Y.; Shapiro, R.; Burgess, R. W.; Yang, X.-L.; Schiavo, G.; Sleigh, J. N.

10.1101/2023.04.09.536152 — neuroscience — Posted on 2024-03-11

3552 The transcriptional response of cortical neurons to concussion reveals divergent fates after injury

Alkaslasi, M. R.; Lloyd, E. Y. H.; Gable, A. S.; Silberberg, H.; Yarur, H. E.; Tsai, V. S.; Tejeda, H. A.; Le Pichon, C. E.

10.1101/2024.02.26.581939 — neuroscience — Posted on 2024-03-11

3553 Spatial, transcriptomic and epigenomic analyses link dorsal horn neurons to chronic pain genetic predisposition

Arokiaraj, C.; Leone, M.; Kleyman, M.; Chamessian, A.; Phan, B. N.; Lopes, B. C.; Cherupally, V. K.; Noh, M.-C.; Corrigan, K. A.; Yeramosu, D.; Franusich, M. E.; Podder, R.; Leie, S.; Shiers, S.; Kang, B.; Kennedy, M.; Dum, R.; Lewis, D.; Qadri, Y.; Price, T.; Pfenning, A.; Seal, R.

10.1101/2022.04.01.486135 — neuroscience — Posted on 2024-03-11

3554 An in silico cardiomyocyte reveals the impact of changes in CAMKII signalling on cardiomyocyte kinetics in hypertrophic cardiomyopathy

Adeniran, I.; Wadee, H.; Degens, H.

10.1101/2023.05.11.540337 — systems biology — Posted on 2024-03-11

3555 Aedes albopictus is not an arbovirus aficionado - Impacts of sylvatic flavivirus infection in vectors and hosts on mosquito engorgement on non-human primates

Cecilia, H.; Althouse, B. M.; Azar, S. R.; Moehn, B. A.; Yun, R.; Rossi, S. L.; Vasilakis, N.; Hanley, K. A.

10.1101/2024.02.19.580944 — systems biology — Posted on 2024-03-11

3556 Light-driven synchronization of optogenetic clocks

Cannarsa, M. C.; Liguori, F.; Pellicciotta, N.; Frangipane, G.; Di Leonardo, R.

10.1101/2023.10.24.563722 — synthetic biology — Posted on 2024-03-11

3557 Learn!Bio - A time-limited cross-sectional study on biosciences students' pathway to resilience during and post the Covid-19 pandemic at an UK university from 2020-2023 and insights into future teaching approaches.

Andrews, K.; Stoneley, R.; Eckl, K.

10.1101/2024.03.06.583815 — scientific communication and education — Posted on 2024-03-11

3558 PEGylated recombinant Aplysia punctata ink toxin depletes arginine and lysine and inhibits growth of tumor xenografts

Wolkersdorfer, A.; Bergmann, B.; Adelmann, J.; Ebbinghaus, M.; Guenther, E.; Gutmann, M.; Hahn, L.; Hurwitz, R.; Kraehmer, R.; Leenders, F.; Luehmann, T.; Schueler, J.; Schmidt, L.; Teifel, M.; Meinel, L.; Rudel, T.

10.1101/2023.01.17.524398 — cancer biology — Posted on 2024-03-11

3559 Integrating single-cell transcriptomics with Artificial Intelligence reveals pan-cancer biomarkers of brain metastasis

Lusby, R.; Carl, S.; Tiwari, V.

10.1101/2024.03.08.584083 — cancer biology — Posted on 2024-03-11

3560 Depth-dependent scaling of axial distances in light microscopy

Loginov, S.; Boltje, D.; Hensgens, M. N. F.; Hoogenboom, J. P.; van der Wee, E.

10.1101/2024.01.31.578242 — biophysics — Posted on 2024-03-11

3561 Integrated Proteomics analysis of baseline protein expression in pig tissues

Wang, S.; Collins, A.; Prakash, A.; Fexova, S.; Papatheodorou, I.; Jones, A. R.; Vizcaino, J. A.

10.1101/2023.11.07.566009 — bioinformatics — Posted on 2024-03-11

3562 Harnessing alkaline-pH regulatable promoters for efficient methanol-free expression of enzymes of industrial interest in Komagataella phaffii

Albacar, M.; Casamayor, A.; Arino, J.

10.1101/2023.12.28.573544 — bioengineering — Posted on 2024-03-11

3563 EXCRETE enables deep proteomics of the microbial extracellular environment

Russo, D. A.; Oliinyk, D.; Pohnert, G.; Meier, F.; Zedler, J. A. Z.

10.1101/2024.03.01.582910 — biochemistry — Posted on 2024-03-11

3564 SIDERITE: Unveiling Hidden Siderophore Diversity in the Chemical Space Through Digital Exploration

He, R.; Gu, S.; Xu, J.; Li, X.; Chen, H.; Shao, Z.; Wang, H.; Shao, J.; Yin, W.-B.; Qian, L.; Wei, Z.; Li, Z.

10.1101/2023.08.31.555687 — biochemistry — Posted on 2024-03-11

3565 DIETS: a simple and sensitive assay to measure and control the intake of complex solid foods, like high-fat diets, in Drosophila

Thakare, M. R.; Choudhary, P.; Pydah, B.; Sunke, S.; Yadav, R. S. P.; Agrawal, P.; Das, G.

10.1101/2023.06.07.543033 — animal behavior and cognition — Posted on 2024-03-11

3566 Imaging genetics of language network functional connectivity reveals links with language-related abilities, dyslexia and handedness

Amelink, J. S.; Postema, M. C.; Kong, X.-Z.; Schijven, D.; Carrion-Castillo, A.; Soheili-Nezhad, S.; Sha, Z.; Molz, B.; Joliot, M.; Fisher, S. E.; Francks, C.

10.1101/2023.11.22.568256 — genomics — Posted on 2024-03-11

3567 Adaptive dynamics, switching environments and the origin of the sexes

Liu, X.; Pitchford, J. W.; Constable, G. W. A.

10.1101/2023.06.09.544312 — evolutionary biology — Posted on 2024-03-11

3568 Idiosyncrasies unveiled: examining the pace, patterns and predictors of biotic diversification in peninsular India

Roy, P.; Joshi, J.

10.1101/2023.11.15.567174 — evolutionary biology — Posted on 2024-03-11

3569 Tree species identity drives soil Carbon and Nitrogen stocks in nutrient-poor sites

Foltran, E. C.; Lamersdorf, N.

10.1101/2023.05.15.540797 — ecology — Posted on 2024-03-11

3570 Age-related dysregulation of the retinal transcriptome in African turquoise killifish

Bergmans, S.; Noel, N. C.; Masin, L.; Harding, E. G.; Krzywanska, A. M.; De Schutter, J. D.; Ayana, R.; Hu, C.-K.; Arckens, L.; Ruzycki, P. A.; Clark, B. S.; MacDonald, R. B.; Moons, L.

10.1101/2024.02.21.581372 — neuroscience — Posted on 2024-03-11

3571 The protective roles of Eugenol on type 1 diabetes mellitus through NRF2 mediated oxidative stress pathway

Jiang, Y.; He, P.; Sheng, K.; Peng, Y.; Wu, H.; Qian, S.; Ji, W.; Guo, X.; Shan, X.

10.1101/2024.03.06.583719 — pharmacology and toxicology — Posted on 2024-03-11

3572 Pharmacological inhibition of macrophage triglyceride biosynthesis pathways does not improve Mycobacterium tuberculosis control in infected mice

Castillo, J. R.; Guerrini, V.; Quijada, D.; Karanika, S.; Neupane, P.; Harris, H.; Garcia, A.; Shenkoya, B.; Yilma, A.; Bailey, H.; Khan, R.; Gopalakrishnan, M.; Gennaro, M. L.; Karakousis, P. C.

10.1101/2024.03.06.583745 — pharmacology and toxicology — Posted on 2024-03-11

3573 Function-Assigned Masked Superstrings as a Versatile and Compact Data Type for ????-Mer Sets

Sladky, O.; Vesely, P.; Brinda, K.

10.1101/2024.03.06.583483 — bioinformatics — Posted on 2024-03-11

3574 Learning tissue representation by identification of persistent local patterns in spatial omics data

Tanevski, J.; Vulliard, L.; Hartmann, F.; Saez-Rodriguez, J.

10.1101/2024.03.06.583691 — bioinformatics — Posted on 2024-03-11

3575 Lit-OTAR Framework for Extracting Biological Evidences from Literature

Tirunagari, S.; Saha, S.; Venkatesan, A.; Suveges, D.; Buniello, A.; Ochoa, D.; McEntyre, J.; McDonagh, E.; Harrison, M.

10.1101/2024.03.06.583722 — bioinformatics — Posted on 2024-03-11

3576 Occurrence and persistence of pseudo-tail spots in the barn swallow

Hasegawa, M.

10.1101/2024.03.06.583633 — evolutionary biology — Posted on 2024-03-11

3577 Mechanisms underlying the loss of migratory behaviour in a long-lived bird

Andrade, P.; Franco, A. M. A.; Acacio, M.; Afonso, S.; Marques, C. I.; Moreira, F.; Carneiro, M.; Catry, I.

10.1101/2024.03.06.583673 — evolutionary biology — Posted on 2024-03-11

3578 Adaptive trade-offs between vertebrate defense and insect predation drive ant venom evolution

Touchard, A.; Robinson, S. D.; Lalague, H.; Ascoet, S.; Billet, A.; Dejean, A.; Tene, N. J.; Petitclerc, F.; Troispoux, V.; Treilhou, M.; Bonnafe, E.; Vetter, I.; Vizueta, J.; Moreau, C. S.; Orivel, J.; Tysklind, N.

10.1101/2024.03.06.583705 — ecology — Posted on 2024-03-11

3579 Ectomycorrhizal fungi are influenced by ecoregion boundaries across Europe

Delhaye, G.; van der Linde, S.; Bauman, D.; Orme, D. C. L.; Suz, L. M.; Bidartondo, M. I.

10.1101/2024.03.06.583687 — ecology — Posted on 2024-03-11

3580 Buzz-world: Global patterns and drivers of buzzing bees and poricidal plants

Russell, A. L.; Buchmann, S. L.; Ascher, J. S.; Wang, Z.; Kriebel, R.; Jolles, D. D.; Orr, M. C.; Hughes, A. C.

10.1101/2024.03.06.583730 — ecology — Posted on 2024-03-11

3581 High-resolution climate data reveals increased risk of Pierce's Disease for grapevines worldwide

Gimenez-Romero, A.; Moralejo, E.; Matias, M. A.

10.1101/2024.03.06.583743 — ecology — Posted on 2024-03-11

3582 Dynamic properties in functional connectivity changes and striatal dopamine deficiency in Parkinson's disease

Asendorf, A. L.; Theis, H.; Tittgemeyer, M.; Timmermann, L.; Fink, G. R.; Drzezga, A.; Eggers, C.; Hoenig, M. C.; van Eimeren, T.

10.1101/2024.03.06.583342 — neuroscience — Posted on 2024-03-11

3583 Asymmetry in synaptic connectivity balances redundancy and reachability in the C. elegans connectome

Birari, V. S.; Rabinowitch, I.

10.1101/2024.03.06.583122 — neuroscience — Posted on 2024-03-11

3584 Non-invasive MRI of Blood-Cerebrospinal Fluid-Barrier Function: a Functional Biomarker of Early Alzheimer's Disease Pathology

Perera, C.; Cruz, R.; Shemesh, N.; Carvalho, T.; Thomas, D. L.; Wells, J.; Ianus, A.

10.1101/2024.03.06.583668 — neuroscience — Posted on 2024-03-11

3585 PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles

Li, L.; He, Z.; Li, Y.; Huang, C.; Hou, W.; Lv, Z.; Zhang, L.; Qu, Y.; Sun, Y.; Huang, K.; Han, X.; Tai, F.-D.

10.1101/2024.03.06.583718 — neuroscience — Posted on 2024-03-11

3586 Maternal Alcohol Drinking Patterns Predict Offspring Neurobehavioral Outcomes

Myrick, A. R.; Jimenez, D.; Jacquez, B.; Noor, S.; Sun, M. S.; Milligan, E. D.; Valenzuela, C. F.; Linsenbardt, D.

10.1101/2024.03.06.583121 — neuroscience — Posted on 2024-03-11

3587 A Novel, Robust, and Portable Platform for Magnetoencephalography using Optically Pumped Magnetometers

Schofield, H.; Hill, R. M.; Feys, O. M.; Holmes, N.; Osborne, J.; Doyle, C.; Bobela, D.; Corvilain, P.; Wens, V.; Rier, L.; Bowtell, R.; Ferez, M.; Mullinger, K. J.; Coleman, S.; Rhodes, N.; Rea, M.; Tanner, Z.; Boto, E.; De Tiege, X.; Shah, V.; Brookes, M. J.

10.1101/2024.03.06.583313 — neuroscience — Posted on 2024-03-11

3588 Mean exercise torque is a critical factor influencing neuromuscular fatigability induced by exhausting contractions

Lebesque, L.; Scaglioni, G.; Martin, A.

10.1101/2024.03.06.583664 — physiology — Posted on 2024-03-11

3589 FGF21 deletion mildly exacerbates hepatic dysfunction in MASH diet and alcohol fed rats

Aldiss, P.; Nielsen, M. H.; Burm, H.; Oro, D.; Hansen, H. H.; Feigh, M.; Gillum, M. P.

10.1101/2024.03.06.583704 — physiology — Posted on 2024-03-11

3590 Air-liquid interface exposure of A549 human lung cells to characterize the hazard potential of a gaseous bio-hybrid fuel blend

Daniel, J.; Schönberger Alvarez, A. A.; te Heesen, P.; Lehrheuer, B.; Pischinger, S.; Hollert, H.; Ross-Nickoll, M.; Du, M.

10.1101/2024.03.06.583741 — pharmacology and toxicology — Posted on 2024-03-11

3591 Comparison of compartmental analytical BOLD fMRI models against Monte Carlo simulations performed over cortical micro-angiograms

Charest, J.; Walsh, M.; Genois, E.; Sevigny, E.; Schwarz, P.-O.; Gagnon, L.; Desjardins, M.

10.1101/2024.03.06.583728 — biophysics — Posted on 2024-03-11

3592 Studying relative RNA localization. From nucleus to the cytosol.

Ntasis, V. F.; Guigo, R.

10.1101/2024.03.06.583744 — bioinformatics — Posted on 2024-03-11

3593 HSV-1 infection induces a downstream-shift of +1 nucleosomes

Weiss, E.; Whisnant, A. W.; Hennig, T.; Djakovic, L.; Doelken, L.; Friedel, C. C.

10.1101/2024.03.06.583707 — bioinformatics — Posted on 2024-03-11

3594 Prediction of Aggregation Prone Regions in Proteins Using Deep Neural Networks and Their Suppression by Computational Design

Cima, V.; Kunka, A.; Grakova, E.; Planas-Iglesias, J.; Havlasek, M.; Subramanian, M.; Beloch, M.; Marek, M.; Slaninova, K.; Damborsky, J.; Prokop, Z.; Bednar, D.; Martinovic, J.

10.1101/2024.03.06.583680 — bioinformatics — Posted on 2024-03-11

3595 U-FISH: a universal deep learning approach for accurate FISH spot detection across diverse datasets

Xu, W.; Cai, H.; Zhang, Q.; Mueller, F.; Ouyang, W.; Cao, G.

10.1101/2024.03.06.583706 — bioinformatics — Posted on 2024-03-11

3596 MotifScope: a multi-sample motif discovery and visualization tool for tandem repeats

Zhang, Y.; Hulsman, M.; Salazar, A.; Tesi, N.; Knoop, L.; van der Lee, S.; Wijesekera, S.; Krizova, J.; Kamsteeg, E.-J.; Holstege, H.

10.1101/2024.03.06.583591 — genomics — Posted on 2024-03-11

3597 The effect of altitude on the expression of immune-related genes in Peruvian rural indigenous

Jaramillo-Valverde, L.; de Araujo, G. S.; Poterico, J. A.; Martinez-Jaramillo, C.; Roa-Linares, V.; Alvites-Arrieta, S.; Pablo-Ramirez, N.; Ubillus, M.; Palma-Lozano, D.; Silva-Carvalho, C.; Vasconcelos-da-Gama, L.; Costa, L. F.; Tarazona-Santos, E.; Raychaudhuri, S.; Guio, H.

10.1101/2024.03.06.583674 — genetics — Posted on 2024-03-11

3598 Interleaved intersectional strategy enables genetic lineage tracing with enhanced specificity

han, m.; liu, z.; huang, x.; liu, l.; zhou, b.; Lui, K.; shu, q.; Zhou, B.

10.1101/2024.03.06.583635 — genetics — Posted on 2024-03-11

3599 A Drosophila model to screen Alport syndrome COL4A5 variants for their functional pathogenicity

Duan, J.; Wen, P.; Zhao, Y.; van de Leemput, J.; Lai, J.; Fermin, D.; Warady, B. A.; Furth, S. L.; Ng, D. K.; Sampson, M.; Han, Z.

10.1101/2024.03.06.583697 — genetics — Posted on 2024-03-11

3600 Ecological diversification in sexual and asexual lineages

Chaparro-Pedraza, C.; Roth, G.; Melian, C.

10.1101/2024.03.06.583698 — evolutionary biology — Posted on 2024-03-11

3601 La Crosse virus reassortants highlight genomic determinants of infection and pathogenesis

Rondeau, N. C.; Spector, S. N.; Thannickal, S. A.; Stapleford, K. A.

10.1101/2024.03.11.584386 — microbiology — Posted on 2024-03-11

3602 Effect of 10 days of unilateral lower limb suspension on knee extensors neuromuscular function and spinal excitability

Lebesque, L.; Narici, M.; Martin, A.; De Vito, G.; Sarto, F.; Scaglioni, G.

10.1101/2024.03.06.583658 — physiology — Posted on 2024-03-11

3603 A Scalable Adaptive Quadratic Kernel Method for Interpretable Epistasis Analysis in Complex Traits

Fu, B.; Anand, P.; Anand, A.; Mefford, J.; Sankararaman, S.

10.1101/2024.03.09.584250 — genetics — Posted on 2024-03-11

3604 WITHDRAWN: Dynamic Regulation of MAVS Protein Function via Reversible Oxidation at Cys79 in Response to Oxidant Stimuli

Zamorano Cuervo, N.; Fortin, A.; Vallejo Arroyo, A.; Dehbidi, L.; Grandvaux, N.

10.1101/2023.08.24.554709 — molecular biology — Posted on 2024-03-11

3605 The functional anatomy of nociception: Effective Connectivity in Chronic Pain and Placebo Responders

Nara, S.; Baliki, M.; Friston, K.; Ray, D.

10.1101/2024.03.10.584304 — neuroscience — Posted on 2024-03-11

3606 A Regularized Cox Hierarchical Model for Incorporating Annotation Information in Predictive Omic Studies

Shen, D.; Lewinger, J. P.

10.1101/2024.03.09.584239 — bioinformatics — Posted on 2024-03-11

3607 Towards Generative RNA Design With Tertiary Interactions

Patil, S.; Runge, F.; Franke, J. K. H.; Hutter, F.

10.1101/2024.03.09.584209 — bioinformatics — Posted on 2024-03-11

3608 Cell type-specific dynamics of prefrontal gamma synchrony during flexible behavior

Phensy, A. J.; Hagopian, L. L.; Sohal, V. S.

10.1101/2024.03.08.584173 — neuroscience — Posted on 2024-03-11

3609 T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption

Gao, Y.; Kennelly, J. P.; Xiao, X.; Whang, E.; Ferrari, A.; Bedard, A. H.; Mack, J. J.; Nguyen, A. H.; Weston, T.; Uchiyama, L. F.; Lee, M. S.; Young, S.; Bensinger, S. J.; Tontonoz, P.

10.1101/2024.03.08.584164 — physiology — Posted on 2024-03-11

3610 Circuits and mechanisms for TMS-induced corticospinal waves: Connecting sensitivityanalysis to the network graph

Yu, G. J.; Ranieri, F.; Di Lazzaro, V.; Sommer, M. A.; Peterchev, A. V.; Grill, W. M.

10.1101/2024.03.05.583549 — neuroscience — Posted on 2024-03-11

3611 SAN: mitigating spatial covariance heterogeneity in cortical thickness data collected from multiple scanners or sites

Zhang, R.; Chen, L.; Oliver, L. D.; Voineskos, A. N.; Park, J. Y.

10.1101/2023.12.04.569619 — neuroscience — Posted on 2024-03-11

3612 LncRNA BRE-AS1 Regulates the JAK2/STAT3-mediated Inflammatory Activation via the miR-30b-5p/SOC3 Axis in THP-1 cells

Shin, J.-J.; Suk, K.; Lee, W.-H.

10.1101/2024.03.06.583653 — immunology — Posted on 2024-03-11

3613 Optimal placement of high-channel visual prostheses in human retinotopic visual cortex

van Hoof, R.; Lozano, A.; Wang, F.; Klink, P. C.; Roelfsema, P. R.; Goebel, R.

10.1101/2024.03.05.583489 — neuroscience — Posted on 2024-03-11

3614 Understanding the complex interplay between tau, amyloid and the network in the spatiotemporal progression of Alzheimer's Disease

Raj, A.; Torok, J.

10.1101/2024.03.05.583407 — neuroscience — Posted on 2024-03-11

3615 Laminar specificity and coverage of viral-mediated gene expression restricted to GABAergic interneurons and their parvalbumin subclass in marmoset primary visual cortex

Federer, F.; Balsor, J.; Ingold, A.; Babcock, D. P.; Dimidschstein, J.; Angelucci, A.

10.1101/2024.03.07.583998 — neuroscience — Posted on 2024-03-11

3616 The neural dynamics of positive and negative expectations of pain

Wittkamp, C. A.; Wolf, M.-I.; Rose, M.

10.1101/2024.03.05.583509 — neuroscience — Posted on 2024-03-11

3617 Earlier finish of motor planning in the premotor cortex predicts faster motor command in the primary motor cortex: human intracranial EEG evidence

Xia, J.; Gong, D.; Han, B.; Guo, Q.; Fink, G. R.; Daun, S.; Chen, Q.

10.1101/2024.03.05.583627 — neuroscience — Posted on 2024-03-11

3618 The Rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

Bao, H.; yanan, w.; Li, H.; Wang, Q.; Lei, Y.; Ye, Y.; Zhu, H.; Stacey, G.; Xu, S.; Cao, Y.

10.1101/2024.03.06.583716 — plant biology — Posted on 2024-03-11

3619 Transcriptional repression of GTL1 under water-deficit stress promotes anthocyanin biosynthesis to enhance drought tolerance

Mano, N. A.; Shaikh, M. A.; Widhalm, J. R.; Yoo, C. Y.; Mickelbart, M. V.

10.1101/2024.03.06.583754 — plant biology — Posted on 2024-03-11

3620 A new group of LysM-RLKs involved in symbiotic signal perception and arbuscular mycorrhiza establishment

Ding, Y.; Gasciolli, V.; Medioni, L.; Gaston, M.; de-Regibus, A.; Rembliere, C.; Bono, J.-J.; Cullimore, J.; Dalmais, M.; Saffray, C.; Mazeau, S.; Bendahmane, A.; Sibout, R.; Vandenbussche, M.; Rouster, J.; Wang, T.; He, G.; Masselin, A.; Cottaz, S.; Fort, S.; Lefebvre, B.

10.1101/2024.03.06.583654 — plant biology — Posted on 2024-03-11

3621 The activation of Chlamydomonas reinhardtii alpha amylase 2 by glutamine requires its N-terminal ACT domain

Scholtysek, L. M.; Poetsch, A.; Hofmann, E.; Hemschemeier, A. C.

10.1101/2024.03.07.583849 — plant biology — Posted on 2024-03-11

3622 XopM, a FFAT motif containing type-III effector protein from Xanthomonas, suppresses PTI responses at the plant plasma membrane

Brinkmann, C.; Bortlik, J.; Raffeiner, M.; Uestuen, S.; Boernke, F.

10.1101/2024.03.06.583702 — plant biology — Posted on 2024-03-11

3623 Stromal DUF760-1 and DUF760-2 proteins are degraded by the chloroplast Clp protease system but have very different half-lives

Yuan, B.; van Wijk, K. J.

10.1101/2024.03.10.584298 — plant biology — Posted on 2024-03-11

3624 Hypsochromic shift of phyC complements the inhibition of hypocotyl elongation under moderate red/far-red light

Yoshihara, S.; Okajima, K.; Tokutomi, S.

10.1101/2024.03.08.584055 — plant biology — Posted on 2024-03-11

3625 MYB68 orchestrates cork differentiation by regulating stem cell proliferation and suberin deposition

Molina, D.; Horvath, S.; Zhang, X.; Xiao, W.; Ragab, N.; Ripper, D.; Kilian, J.; Andersen, T. G.; Ragni, L.

10.1101/2024.03.06.583666 — plant biology — Posted on 2024-03-11

3626 Structure-aware protein sequence alignment using contrastive learning

You, R.; Yi, Y.; Zhu, S.

10.1101/2024.03.09.583681 — bioinformatics — Posted on 2024-03-11

3627 OligoY pipeline for full Y chromosome painting

Almeida, I.; Bonilla Bruno, H.; Lisboa Santana Pinheiro, M. M.; Bernardo de Carvalho, A.; Vibranovski, M. D.

10.1101/2024.03.06.583648 — bioinformatics — Posted on 2024-03-11

3628 Quorum sensing in Mycobacteria: understanding the recognition machinery conundrum through an in-silico approach

Janakiraman, v.; PHANI SARATH TEJA, K.

10.1101/2024.03.06.583649 — bioinformatics — Posted on 2024-03-11

3629 Using Multivariate Pattern Analysis to Increase Effect Sizes for Event-Related Potential Analyses

Carrasco, C. D.; Bahle, B.; Simmons, A. M.; Luck, S. J.

10.1101/2023.11.07.566051 — neuroscience — Posted on 2024-03-11

3630 Uncertainty-based causal inference modulates audiovisual temporal recalibration

Li, L.; Hong, F.; Badde, S.; Landy, M. S.

10.1101/2024.03.08.584189 — neuroscience — Posted on 2024-03-11

3631 Beta bursts in the parkinsonian cortico-basal ganglia network form spatially discrete ensemble.

Grennan, I.; Mallet, N. P.; Magill, P. J.; Cagnan, H.; Sharott, A.

10.1101/2024.03.05.583301 — neuroscience — Posted on 2024-03-11

3632 Two new qPCR assays for detecting and quantifying the Aspergillus flavus and Aspergillus parasiticus clades in maize kernels

Leharanger, A.; Paumier, D.; Orlando, B.; Bailly, S.; VALADE, R.

10.1101/2024.03.06.583514 — pathology — Posted on 2024-03-11

3633 The Molecular Basis for Hydrodynamic Properties of PEGylated Human Serum Albumin

Fleming, P.; Correia, J. J.; Fleming, K. G.

10.1101/2024.03.05.583576 — biophysics — Posted on 2024-03-11

3634 Community structure and temporal dynamics of SARS-CoV-2 epistatic network allow for early detection of emerging variants with altered phenotypes

Mohebbi, F.; Zelikovsky, A.; Mangul, S.; Chowell, G.; Skums, P.

10.1101/2023.04.02.535277 — bioinformatics — Posted on 2024-03-11

3635 A model of task-level human stepping regulation yields semistable walking

Patil, N. S.; Dingwell, J. B.; Cusumano, J. P.

10.1101/2024.03.05.583616 — bioengineering — Posted on 2024-03-11

3636 Scalable summary statistics-based heritability estimation method with individual genotype level accuracy

Jeong, M.; Pazokitoroudi, A.; Liu, Z.; Sankararaman, S.

10.1101/2024.03.09.584258 — genomics — Posted on 2024-03-11

3637 Parsimonious EBM: generalising the event-based model of disease progression for simultaneous events

Parker, C. S.; Oxtoby, N. P.; Young, A. L.; Alzheimer's Disease Neuroimaging Initiative, ; Alexander, D. C.; Zhang, H.

10.1101/2022.07.10.499471 — neuroscience — Posted on 2024-03-11

3638 Neuronal substance-P drives breast cancer growth and metastasis via an extracellular RNA/TLR7 axis

Padmanaban, V.; Keller, I.; Seltzer, E. S.; Ostendorf, B. N.; Kerner, Z.; Tavazoie, S. F.

10.1101/2024.03.08.584128 — cancer biology — Posted on 2024-03-11

3639 Genetics-driven Risk Predictions with Differentiable Mendelian Randomization

Sens, D. W.; Gräph, L.; Shilova, L.; Casale, F.-P.

10.1101/2024.03.06.583727 — bioinformatics — Posted on 2024-03-11

3640 Making Moral Decisions With Artificial Agents As Advisors. An fNIRS Study

Fabre, E. F.; Mouratille, D.; Bonnemain, V.; Palmiotti, G.-P.; Causse, M.

10.1101/2024.03.05.583335 — neuroscience — Posted on 2024-03-11

3641 Dopamine dynamics in chronic pain: music-induced sex-dependent behavioral effects in mice

Flores-Garcia, M.; Flores de los Heros, A.; Aso, E.; Grau-Sanchez, J.; Videla, S.; Rodriguez-Fornells, A.; Bonaventura, J.; Fernandez-Duenas, V.

10.1101/2024.03.05.583510 — neuroscience — Posted on 2024-03-11

3642 Structure-based discovery of CFTR potentiators and inhibitors

Liu, F.; Kaplan, A. L.; Levring, J.; Einsiedel, J.; Tiedt, S.; Distler, K.; Omattage, N.; Kondratov, I. S.; Moroz, Y. S.; Pietz, H. L.; Irwin, J. J.; Gmeiner, P.; Shoichet, B. K.; Chen, J.

10.1101/2023.09.09.557002 — biophysics — Posted on 2024-03-11

3643 hAMRonization: Enhancing antimicrobial resistance prediction using the PHA4GE AMR detection specification and tooling

Mendes, I.; Griffiths, E.; Manuele, A.; Fornika, D.; Tausch, S. H.; Le Viet, T.; Phelan, J.; Meehan, C. J.; Raphenya, A. R.; Alcock, B.; Culp, E. J.; Lorenzo, F.; Haim, M. S.; Witney, A.; Black, A.; Katz, L.; Oluniyi, P.; Olawoye, I.; Timme, R. E.; Neoh, H.-m.; Lam, S. D.; Jamaluddin, T. Z. M. T.; Nathan, S.; Ang, M. Y.; Di Gregorio, S.; Vandelannoote, K.; Dusadeepong, R.; Chindelevitch, L.; Nasar, M. I.; Aanensen, D.; Afolayan, A. O.; Odih, E. E.; McArthur, A. G.; Feldgarden, M.; Galas, M. M.; Campos, J.; Okeke, I. N.; Underwood, A.; Page, A. J.; MacCannell, D.; Maguire, F.

10.1101/2024.03.07.583950 — bioinformatics — Posted on 2024-03-11

3644 Unveiling the Microbial Realm with VEBA 2.0: A modular bioinformatics suite for end-to-end genome-resolved prokaryotic, (micro)eukaryotic, and viral multi-omics from either short- or long-read sequencing

Espinoza, J. L.; Phillips, A.; Prentice, M. B.; Tan, G. S.; Kamath, P. L.; Lloyd, K. G.; Dupont, C. L.

10.1101/2024.03.08.583560 — bioinformatics — Posted on 2024-03-11

3645 SaProt: Protein Language Modeling with Structure-aware Vocabulary

Su, J.; Han, C.; Zhou, Y.; Shan, J.; Zhou, X.; Yuan, F.

10.1101/2023.10.01.560349 — bioinformatics — Posted on 2024-03-11

3646 Risk-sensitive learning is a winning strategy for leading an urban invasion

Breen, A. J.; Deffner, D.

10.1101/2023.03.19.533319 — animal behavior and cognition — Posted on 2024-03-11

3647 Cross-continental variation of herbivore resistance in a global plant invader

Cao, P.; Liao, Z.; Zhang, L.; Wang, S.; Bi, J.; Zhao, Y.; Parepa, M.; Lin, T.; Guo, Y.; Bossdorf, O.; Richards, C. L.; Endriss, S. B.; Wu, J.; Ju, R.; Li, B.

10.1101/2023.12.13.571471 — ecology — Posted on 2024-03-11

3648 Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex

Guo, Q.; Chen, K.-E.; Gimenez-Andres, M.; Jellett, A.; Gao, Y.; Simonetti, B.; Liu, M.; Danson, C.; Heesom, K. J.; Cullen, P. J.; Collins, B. M.

10.1101/2023.08.15.553351 — cell biology — Posted on 2024-03-11

3649 RNPS1 in PSAP complex controls periodic pre-mRNA splicing over the cell cycle

Fukumura, K.; Masuda, A.; Takeda, J.-i.; Ohno, K.; Mayeda, A.

10.1101/2023.11.20.567984 — molecular biology — Posted on 2024-03-11

3650 Spatial patterns of Hyalomma marginatum-borne pathogens in the Occitanie region (France), a focus on the intriguing dynamics of Rickettsia aeschlimannii

KUKLA, C. J.; Bernard, C.; Bru, D.; Galon, C.; Giupponi, C.; Huber, K.; Jourdan-Pineau, H.; Malandrin, L.; Rakotoarivony, I.; Riggi, C.; Vial, L.; Moutailler, S.; Pollet, T.

10.1101/2024.03.05.583534 — microbiology — Posted on 2024-03-11

3651 Multi-taskLearning and Ensemble Approach to Predict Cognitive Scores for Patients with Alzheimer's Disease

Ma, D.; Pabalan, C.; Rajagopal, A.; Akanksha, A.; Interian, Y.; Yang, Y.; Raj, A.

10.1101/2021.12.08.471856 — neuroscience — Posted on 2024-03-11

3652 Modelling Glioma Stem Cell-mediated Tumorigenesis Using Zebrafish PDX Systems

Mahendran, H. P.; Cieslukowski, A.; Lubanska, D.; Philbin, N.; Stringer, K. F.; Habashy, P.; Stover, M.; deCarvalho, A.; Soliman, M.; Shamisa, A.; Porter, L.

10.1101/2024.02.27.580776 — cancer biology — Posted on 2024-03-11

3653 EnhancerBD identifing sequence feature

wang, y.

10.1101/2024.03.05.583459 — bioinformatics — Posted on 2024-03-11

3654 Obstacle Negotiation in Female Locust Oviposition Digging

Klechevski, C.; Kats, L.; Ayali, A.

10.1101/2024.03.05.583468 — animal behavior and cognition — Posted on 2024-03-11

3655 Cognitive modeling of the Mnemonic Similarity Task as a digital biomarker for Alzheimer's Disease

Vanderlip, C.; Lee, M.; Stark, C.

10.1101/2024.03.07.584012 — neuroscience — Posted on 2024-03-11

3656 Methodological choices matter: A systematic comparison of TMS-EEG studies targeting the primary motor cortex

Beck, M. M.; Heyl, M.; Mejer, L.; Vinding, M. C.; Christiansen, L.; Tomasevic, L.; Siebner, H. R.

10.1101/2024.03.08.583873 — neuroscience — Posted on 2024-03-11

3657 Integrating single-cell transcriptomics with Artificial Intelligence reveals pan-cancer biomarkers of brain metastasis

Tiwari, V.; Lusby, R.; Carl, S.

10.1101/2024.03.08.584083 — cancer biology — Posted on 2024-03-11

3658 AllTheBacteria - all bacterial genomes assembled, available and searchable

Hunt, M.; Lima, L.; Shen, W.; Lees, J.; Iqbal, Z.

10.1101/2024.03.08.584059 — bioinformatics — Posted on 2024-03-11

3659 Role of the right middle occipital gyrus in egocentric spatial orientation in reference to gravitational information: Evidence from a pre-registered rTMS study

Tani, K.; Naito, E.; Mizobe, K.; Hirose, S.

10.1101/2024.03.07.584011 — neuroscience — Posted on 2024-03-11

3660 Normative models combining fetal and postnatal MRI data to characterize neurodevelopmental trajectories during the transition from in- to ex-utero

Mihailov, A.; Pron, A.; Lefevre, J.; Deruelle, C.; Desnous, B.; Bretelle, F.; Manchon, A.; Milh, M.; Rousseau, F.; Auzias, G.; Girard, N.

10.1101/2024.03.07.583908 — neuroscience — Posted on 2024-03-11

3661 Persistent cognitive deficits in anti-LGI1 encephalitis are linked to a reorganization of structural brain networks

Krohn, S.; Mueller-Jensen, L.; Kuchling, J.; Romanello, A.; Bartsch, T.; Leypoldt, F.; Paul, F.; Pruess, H.; Finke, C.

10.1101/2024.03.07.583948 — neuroscience — Posted on 2024-03-11

3662 LPOR and the membranes - evolutionary pathway towards prolamellar body formation

Ogrodzinska, W.; Szafran, K.; Luszczynski, M.; Woznicka, O.; Gabruk, M.

10.1101/2024.03.08.584095 — biochemistry — Posted on 2024-03-11

3663 Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing

Lodewijk, G. A.; Kozuki, S.; Han, C.; Topacio, B. R.; Zargari, A.; Lee, S.; Knight, G.; Ashton, R.; Qi, L. S.; Shariati, S. A.

10.1101/2024.03.05.583597 — developmental biology — Posted on 2024-03-11

3664 HIV-1 Nef acts in synergy with APOL1-G1 to induce nephrocyte cell death in a new Drosophila model of HIV-related kidney diseases

Zhu, J.-y.; Fu, Y.; van de Leemput, J.; Yu, Y.; Li, J.; Ray, P. E.; Han, Z.

10.1101/2024.03.08.584069 — molecular biology — Posted on 2024-03-11

3665 High-throughput Screening of Compounds against Autoluminescent Nonreplicating Mycobacterium tuberculosis under Diverse Conditions

Tian, X.; Ma, W.; Yusuf, B.; Li, C.; Hameed, H. M. A.; Wang, X.; Zhong, N.; Hu, J.; Zhang, T.

10.1101/2024.03.10.584296 — microbiology — Posted on 2024-03-11

3666 Nucleomorph phylogenomics suggests a deep and ancient origin of cryptophyte plastids within Rhodophyta

Novak, L. V. F.; Munoz-Gomez, S. A.; van Beveren, F.; Ciobanu, M.; Eme, L.; Lppez-Garcia, P.; Moreira, D.

10.1101/2024.03.10.584144 — microbiology — Posted on 2024-03-11

3667 Gut Eggerthella lenta promotes the efficacy of resveratrol through reductive metabolism

Dong, Z.; Jiang, W.

10.1101/2024.03.10.584274 — microbiology — Posted on 2024-03-11

3668 Single molecule fingerprinting reveals different growth mechanisms in seed amplification assays for different polymorphs of alpha Synuclein fibrils.

Lau, D.; Tang, Y.; Kenche, V.; Copie, T.; Kempe, D.; Jary, E.; Graves, N. J.; Biro, M.; Masters, C. L.; Dzamko, N.; Gambin, Y.; Sierecki, E.

10.1101/2024.03.05.583619 — neuroscience — Posted on 2024-03-11

3669 TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease models

Andreasson, K. I.; Wilson, E. N.; Wang, C.; Xin, M.; Panchal, M.; Rabinowitz, J. D.; Minhas, P. S.; Swarovski, M. S.; Benitez, J. A. R.; Durairaj, A. S.; Chaney, A.; Iweka, C. A.; Buckwalter, M. S.; Ennerfelt, H. E.; Umans, J.; Huang, J.; Zera, K. A.; McReynolds, M. R.; Greicius, M. D.; James, M. L.; Mehta, S. S.; Le Guen, Y.; Tan, Y. J.; Zuckerman, A. J.; Blacher, E.; Gauba, E.; Serrano, G. E.; Cropper, H.; Jain, P.; Liu, Q.

10.1101/2024.03.05.583562 — neuroscience — Posted on 2024-03-11

3670 Enhancing Gastrodin Production in Yarrowia lipolytica by Metabolic Engineering

Wu, Y.; Li, S.; Sun, B.; Guo, J.; Zheng, M.; Li, A.

10.1101/2024.03.10.584284 — synthetic biology — Posted on 2024-03-11

3671 Reconfigurable multi-component nanostructures built from DNA origami voxels

Luu, M. T.; Berengut, J.; Daljit Singh, J. K.; Coffi Dit Glieze, K.; Turner, M.; Skipper, K.; Meppat, S.; Abbas, A.; Fowler, H.; Close, W.; Doye, J. P. K.; Wickham, S. F. J.

10.1101/2024.03.10.584331 — synthetic biology — Posted on 2024-03-11

3672 Off-target depletion of plasma tryptophan by allosteric inhibitors of BCKDK

Bowman, C. E.; Neinast, M. D.; Jang, C.; Patel, J.; Blair, M. C.; Mirek, E. T.; Jonsson, W. O.; Chu, Q.; Merlo, L.; Mandik-Nayak, L.; Anthony, T. G.; Rabinowitz, J. D.; Arany, Z.

10.1101/2024.03.05.582974 — pharmacology and toxicology — Posted on 2024-03-11

3673 Applicability of AlphaFold2 in the modelling of coiled-coil domains

Madaj, R.; Martinez-Goikoetxea, M.; Kaminski, K.; Ludwiczak, J.; Dunin-Horkawicz, S.

10.1101/2024.03.07.583852 — bioinformatics — Posted on 2024-03-10

3674 Molecular Genomic Insights into Melanoma Associated Proteins PRAME and BAP1

Nawn, D.; Hassan, S. S.; Hromic Jahjefendic, A.; Bhattacharya, T.; Basu, P.; Redwan, E. M.; Barh, D.; Andrade, B.; Aljabali, A. A.; Serrano Aroca, A.; Lundstrom, K.; Tambuwala, M. M.; Uversky, V. N.

10.1101/2024.03.05.583532 — bioinformatics — Posted on 2024-03-11

3675 Uncalled4 improves nanopore DNA and RNA modification detection via fast and accurate signal alignment

Kovaka, S.; Hook, P. W.; Jenike, K. M.; Shivakumar, V.; Morina, L. B.; Razaghi, R.; Timp, W.; Schatz, M. C.

10.1101/2024.03.05.583511 — bioinformatics — Posted on 2024-03-11

3676 Analysis and visualization of quantitative proteomics data using FragPipe-Analyst

Hsiao, Y.; Zhang, H.; Li, G. X.; Deng, Y.; Yu, F.; Kahrood, H. V.; Steele, J. R.; Schittenhelm, R. B.; Nesvizhskii, A. I.

10.1101/2024.03.05.583643 — bioinformatics — Posted on 2024-03-11

3677 De Novo Transcriptome Analysis Reveals Novel Insights into Secondary Metabolite Biosynthesis in Tylophora indica (Burm. f) Merrill.

Gupta, A.; Singh, D.; Ranjan, R.

10.1101/2024.03.05.583525 — bioinformatics — Posted on 2024-03-11

3678 zIncubascope: long-term quantitative imaging of multi-cellular assemblies inside an incubator

Jana, A.; Mekhileri, N.; Boyreau, A.; Bazin, A.; Pujol, N.; Alessandri, K.; Recher, G.; Nassoy, P.; Badon, A.

10.1101/2024.03.05.583476 — bioengineering — Posted on 2024-03-10

3679 Supramolecular complexes of GCAP1: towards the development of effective biologics for inherited retinal dystrophies

Biasi, A.; Marino, V.; Dal Cortivo, G.; Dell'Orco, D.

10.1101/2024.03.07.583919 — biochemistry — Posted on 2024-03-11

3680 Introducing CHiDO a No Code Genomic Prediction Software implementation for the Characterization & Integration of Driven Omics

Gonzalez, F.; Garcia-Abadillo, J.; Jarquin, D.

10.1101/2024.03.05.583604 — genomics — Posted on 2024-03-11

3681 Structure-based probe reveals the presence of large transthyretin aggregates in plasma of ATTR amyloidosis patients

Pedretti, R.; Wang, L.; Yakubovska, A.; Zhang, Q. S.; Nguyen, B.; Grodin, J. L.; Masri, A.; Saelices, L.

10.1101/2024.03.09.584228 — molecular biology — Posted on 2024-03-10

3682 Improved functions for non-linear sequence comparison using SEEKR

Li, S.; Eberhard, Q.; Ni, L.; Calabrese, M.

10.1101/2024.03.10.584286 — molecular biology — Posted on 2024-03-10

3683 Dietary restriction reveals sex-specific expression of the mTOR pathway genes in Japanese quails

Reda, G. K.; Ndunguru, S. F.; Csernus, B.; Knop, R.; Lugata, J. K.; Szabo, C.; Czegledi, L.; Lendvai, A. Z.

10.1101/2024.03.10.584307 — molecular biology — Posted on 2024-03-11

3684 Extremely acidic proteomes and metabolic flexibility in bacteria and highly diversified archaea thriving in geothermal chaotropic brines

Gutierrez-Preciado, A.; Dede, B.; Baker, B.; Eme, L.; Moreira, D.; Lopez-Garcia, P.

10.1101/2024.03.10.584303 — microbiology — Posted on 2024-03-10

3685 Pf bacteriophages hinder sputum antibiotic diffusion via electrostatic binding

Chen, Q.; Cai, P.; Chang, T. H. W.; Burgener, E.; Kratochvil, M. J.; Gupta, A.; Hargil, A.; Secor, P. R.; Nielsen, J. E.; Barron, A. E.; Milla, C.; Heilshorn, S. C.; Spakowitz, A. J.; Bollyky, P. L.

10.1101/2024.03.10.584330 — microbiology — Posted on 2024-03-10

3686 Cas1 mediates the interference stage in a phage-encoded CRISPR-Cas system

Zhang, L.; Wang, H.; Zeng, J.; Cao, X.; Gao, Z.; Liu, Z.; Li, F.; Wang, J.; Zhang, Y.; Yang, M.; Feng, Y.

10.1101/2024.03.09.584257 — microbiology — Posted on 2024-03-11

3687 Myc Dysregulation in Activated Macrophages Initiates Iron-Mediated Lipid Peroxidation that Fuels Type I Interferon and Compromises TB Resistance

Yabaji, S. M.; Zhernovkov, V.; Araveti, P. B.; Lata, S.; Rukhlenko, O. S.; Abdullatif, S. A.; Alekseev, Y.; Ma, Q.; Dayama, G.; Lau, N. C.; Bishai, W. R.; Crossland, N. A.; Campbell, J. D.; Kholodenko, B. N.; Gimelbrant, A. A.; Kobzik, L.; Kramnik, I.

10.1101/2024.03.05.583602 — immunology — Posted on 2024-03-10

3688 T cell polarization and NFAT translocation are stiffness-dependent and are differentially regulated by Piezo1 and Orai1

Zhao, R.; Zhang, J.; Schwarz, E. C.; Campo, A. d.; Hoth, M.; Qu, B.

10.1101/2024.03.06.583253 — immunology — Posted on 2024-03-11

3689 Altered circadian rhythm, sleep, and rhodopsin 7-dependent shade preference during diapause in Drosophila melanogaster

Meyerhhof, G. T.; Easwaran, S.; Bontempo, A. E.; Montell, C.; Montell, D.

10.1101/2024.03.09.584236 — neuroscience — Posted on 2024-03-10

3690 Maximum Likelihood Inference of Time-scaled Cell Lineage Trees with Mixed-type Missing Data

Mai, U.; Chu, G.; Raphael, B.

10.1101/2024.03.05.583638 — systems biology — Posted on 2024-03-10

3691 Identifying effective evolutionary strategies for uncovering reaction kinetic parameters under the effect of measurement noises

Yeo, H. C.; Varsheni, V.; Selvarajoo, K.

10.1101/2024.03.05.583637 — systems biology — Posted on 2024-03-10

3692 Histology-guided mathematical model of tumor oxygenation: sensitivity analysis of physical and computational parameters

Ojwang', A. M. E.; Bazargan, S.; Johnson, J. O.; Pilon-Thomas, S.; Rejniak, K. A.

10.1101/2024.03.05.583363 — systems biology — Posted on 2024-03-10

3693 MetaWorm: An Integrative Data-Driven Model Simulating C. elegans Brain, Body and Environment Interactions

Zhao, M.; Wang, N.; Jiang, X.; Ma, X.; Ma, H.; He, G.; Du, K.; Ma, L.; Huang, T.

10.1101/2024.02.22.581686 — neuroscience — Posted on 2024-03-10

3694 Valency of Ligand-Receptor Binding from Pair Potentials

Morton, W.; Vacha, R.; Angioletti-Uberti, S.

10.1101/2023.09.12.557452 — biophysics — Posted on 2024-03-10

3695 de novo diploid genome assembly using long noisy reads

Nie, F.; Ni, P.; Huang, N.; Zhang, J.; Wang, Z.; Xiao, C.-L.; Luo, F.; Wang, J.

10.1101/2022.09.25.509436 — bioinformatics — Posted on 2024-03-10

3696 On the identification of differentially-active transcription factors from ATAC-seq data

Gerbaldo, F.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.

10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-03-10

3697 Leveraging multiple data types for improved compound-kinase bioactivity prediction

Theisen, R.; Wang, T.; Ravikumar, B.; Rahman, R.; Cichonska, A.

10.1101/2024.03.07.583951 — bioinformatics — Posted on 2024-03-10

3698 Sequence-based Protein-Protein Interaction Prediction Using Multi-kernel Deep Convolutional Neural Networks with ProteinLanguage Model

Dang, T. H.; Vu, T. A.

10.1101/2023.10.03.560728 — bioinformatics — Posted on 2024-03-10

3699 Expectation-Maximization enables Phylogenetic Dating under a Categorical Rate Model

Mai, U.; Charvel, E.; Mirarab, S.

10.1101/2022.10.06.511147 — bioinformatics — Posted on 2024-03-10

3700 Dynamically stiffening biomaterials reveal age- and sex-specific differences in pulmonary arterial adventitial fibroblast activation

Mueller, M. C.; Du, Y.; Walker, L. A.; Magin, C. M.

10.1101/2023.05.11.540410 — bioengineering — Posted on 2024-03-10

3701 Longevity and environmental temperature modulate mitochondrial DNA evolution in fishes

Le Cam, S.; Mortz, M.; Blier, P.

10.1101/2024.03.07.583929 — evolutionary biology — Posted on 2024-03-10

3702 The information theory formalism unifies the detection of the patterns of sexual selection and assortative mating for both discrete and quantitative traits

Carvajal-Rodriguez, A.

10.1101/2023.08.14.552693 — evolutionary biology — Posted on 2024-03-10

3703 Saltational episodes of reticulate evolution in the Drosophila saltans species group

Prediger, C.; Ferreira, E. A.; Zorzato, S. V.; Hua-Van, A.; Klasson, L.; Miller, W.; Yassin, A.; Madi-Ravazzi, L.

10.1101/2023.10.09.561511 — evolutionary biology — Posted on 2024-03-10

3704 Functional stress responses in Glaucophyta: evidence of ethylene and abscisic acid functions in Cyanophora paradoxa.

Genot, B.; Grogan, M.; Yost, M.; Iacono, G.; Archer, S. D.; Burns, J. A.

10.1101/2023.06.22.546102 — evolutionary biology — Posted on 2024-03-10

3705 Nitrogen niche partitioning between tropical legumes and grasses conditionally weakens under elevated CO2

Churchill, A. C.; Zhang, H.; Kim, G. w.; Catunda, K. L. M.; Anderson, I. C.; Isbell, F. I.; Moore, B.; Pendall, E.; Plett, J. M.; Powell, J.; Power, S. A.

10.1101/2023.01.16.524162 — ecology — Posted on 2024-03-10

3706 Cross-continental variation of herbivore resistance in a global plant invader

Cao, P.; Liao, Z.; Wang, S.; Zhang, L.; Lin, T.; Parepa, M.; Bi, J.; Zhao, Y.; Guo, Y.; Bossdorf, O.; Richards, C. L.; Endriss, S. B.; Wu, J.; Ju, R.; Li, B.

10.1101/2023.12.13.571471 — ecology — Posted on 2024-03-10

3707 A host AAA-ATPase exhibits bacteriolytic activity for clearance of microbial infection

Ghosh, S.; Roy, S.; Baid, N.; Das, U. K.; Rakshit, S.; Sanghavi, P.; Hajra, D.; Menon, S.; Sahil, M.; Shaw, S.; Rajmani, R. S.; Adicherla, H.; Mondal, J.; Chakravortty, D.; Mallik, R.; Banerjee, A.

10.1101/2023.07.18.549519 — cell biology — Posted on 2024-03-10

3708 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS

Appleton, E. M.; Hong, K.; Rodriguez-Caycedo, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.

10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-10

3709 On-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures

Onal, S.; Alkaisi, M. M.; Nock, V.

10.1101/2024.02.28.582630 — cell biology — Posted on 2024-03-10

3710 Ipsilateral restriction of chromosome movement along a centrosome, and apical-basal axis during the cell cycle

Cai, P.; Casas, C. J.; Quintero Plancarte, G.; Hua, L. L.; Mikawa, T.

10.1101/2023.03.27.534352 — cell biology — Posted on 2024-03-10

3711 Risk assessment predicts most of the salmonellosis risk in raw chicken parts is concentrated in those few products with high-levels of high-virulent serotypes of Salmonella

Kim, M.; Barnett-Neefs, C.; Chavez, R. A.; Kealey, E.; Wiedmann, M.; Stasiewicz, M. J.

10.1101/2024.03.08.584166 — microbiology — Posted on 2024-03-10

3712 Beyond the Delay Neural Dynamics: a Decoding Strategy for Working Memory Error Reduction

Ye, Z.; Li, H.; Tian, L.; Zhou, C.

10.1101/2022.06.01.494426 — neuroscience — Posted on 2024-03-10

3713 SAMson: an automated brain extraction tool for rodents using SAM

Soler, D. P.; Selim, M. K.; Munoz-Moreno, E.; Ramos-Cabrer, P.; Lopez-Larrubia, P.; Pertusa, A.; De Santis, S.; Canals, S.

10.1101/2024.03.07.583982 — neuroscience — Posted on 2024-03-10

3714 Phylogenomics defines Streptofilum as a novel deep branch of streptophyte algae

Zarsky, V.; Elias, M.

10.1101/2024.03.08.584070 — plant biology — Posted on 2024-03-10

3715 Manipulating condensation of thermo-sensitive SUF4 protein tunes flowering time in Arabidopsis thaliana

Meyer, H. M.; Hotta, T.; Malkovskiy, A.; Zheng, Y.; Ehrhardt, D. W.

10.1101/2023.11.01.565081 — plant biology — Posted on 2024-03-10

3716 Evolution-Aware Deep Reinforcement Learning for Single-Cell DNA Copy Number Calling

Ivanovic, S.; El-Kebir, M.

10.1101/2024.03.08.583988 — cancer biology — Posted on 2024-03-10

3717 The molecular architecture of the desmosomal outer dense plaque by integrative structural modeling

Pasani, S.; Menon, K. S.; Viswanath, S.

10.1101/2023.06.13.544884 — biophysics — Posted on 2024-03-10

3718 123FASTQ: an intuitive and efficient tool for preprocessing Illumina FASTQ reads

Eidi, M.; Abdolalizadeh, S.; Nasirpour, M. H.; Zahiri, J.; Garshasbi, M.

10.1101/2024.03.08.584032 — bioinformatics — Posted on 2024-03-10

3719 Next-generation sequencing analysis with a population-specific reference genome

Suzuki, T.; Ninomiya, K.; Funayama, T.; Okamura, Y.; Tadaka, S.; the Tohoku Medical Megabank Project Study Group, ; Kinoshita, K.; Yamamoto, M.; Kure, S.; Kikuchi, A.; Tamiya, G.; Takayama, J.

10.1101/2024.03.07.584017 — bioinformatics — Posted on 2024-03-10

3720 Unveiling the Microbial Realm with VEBA 2.0: A modular bioinformatics suite for end-to-end genome-resolved prokaryotic, (micro)eukaryotic, and viral multi-omics from either short- or long-read sequencing

Espinoza, J. L.; Phillips, A.; Prentice, M. B.; Tan, G. S. L.; Kamath, P. L.; Lloyd, K. G.; Dupont, C. L.

10.1101/2024.03.08.583560 — bioinformatics — Posted on 2024-03-10

3721 DeST-OT: Alignment of Spatiotemporal Transcriptomics Data

Halmos, P.; Liu, X.; Gold, J.; Chen, F.; Ding, L.; Raphael, B.

10.1101/2024.03.05.583575 — bioinformatics — Posted on 2024-03-10

3722 How low can you go? Short-read polishing of Oxford Nanopore bacterial genome assemblies

Bouras, G.; Judd, L. M.; Edwards, R. A.; Vreugde, S.; Stinear, T. P.; Wick, R. R.

10.1101/2024.03.07.584013 — bioinformatics — Posted on 2024-03-10

3723 Variation and interaction of distinct subgenomes contribute to growth diversity in intergeneric hybrid fish

Ren, L.; Luo, M.; Cui, J.; Gao, X.; Zhang, H.; Wu, P.; Wei, Z.; Tai, Y.; Li, M.; Luo, K.; Liu, S.

10.1101/2024.03.07.584006 — genetics — Posted on 2024-03-10

3724 Strain heterogeneity in a non-pathogenic fungus highlights factors contributing to virulence

Rinker, D. C.; Sauters, T. J. C.; Steffen, K.; Gumilang, A.; Raja, H. A.; Rangel-Grimaldo, M.; Pinzan, C. F.; de Castro, P. A.; dos Reis, T. F.; Delbaje, E.; Houbraken, J.; Goldman, G. H.; Oberlies, N. H.; Rokas, A.

10.1101/2024.03.08.583994 — evolutionary biology — Posted on 2024-03-10

3725 metaRange: A framework to build mechanistic range models

Fallert, S.; Li, L.; Sarmento Cabral, J.

10.1101/2024.03.07.583922 — ecology — Posted on 2024-03-10

3726 Sex-specific sub-lethal effects of low virulence entomopathogenic fungi may boost the Sterile Insect Technique

duneau, d.; Gallet, R.; Adhiambo, M.; Deletre, E.; Chailleux, A.; Khamis, F.; Subramanian, S.; Brevault, T.; Fellous, S.

10.1101/2024.03.07.583916 — ecology — Posted on 2024-03-10

3727 Urban Cepaea nemoralis snails are less likely to have nematodes trapped within their shells

Dahirel, M.; Reyne, H.; De Wolf, K.; Bonte, D.

10.1101/2024.03.07.583959 — ecology — Posted on 2024-03-10

3728 Identification of Neural Crest and Neural Crest-Derived Cancer Cell Invasion and Migration Genes Using High-throughput Screening and Deep Attention Networks

Kasemeier-Kulesa, J. C.; Martina Perez, S.; Baker, r. E.; Kulesa, P. M.

10.1101/2024.03.07.583913 — developmental biology — Posted on 2024-03-10

3729 Morphology, but not microtubules, of the retinal nerve fibers are protected by nicotinamide in glaucoma mice

Boodram, V.; Lim, H.

10.1101/2024.03.07.583928 — neuroscience — Posted on 2024-03-10

3730 Comparing Automated Subcortical Volume Estimation Methods; Amygdala Volumes Estimated by FSL and FreeSurfer Have Poor Consistency

Sadil, P.; Lindquist, M. A.

10.1101/2024.03.07.583900 — neuroscience — Posted on 2024-03-10

3731 A reference database of reptile images

Uetz, P. H.; Patel, M.; Gbadamosi, Z.; Shoope, S.; Nguyen, J.

10.1101/2024.03.08.584020 — zoology — Posted on 2024-03-10

3732 Active fluctuations of cells reduce friction to enable fast and coherent collective migration

Jipp, M.; Wagner, B. D.; Egbringhoff, L.; Teichmann, A.; Ruebeling, A.; Nieschwitz, P.; Honigmann, A.; Chizhik, A.; Oswald, T. A.; Janshoff, A.

10.1101/2024.03.07.583903 — biophysics — Posted on 2024-03-10

3733 The strength of sexual signals predicts same-sex paring in termites

Mizumoto, N.; Lee, S.-B.; Chouvenc, T.

10.1101/2024.03.07.583902 — animal behavior and cognition — Posted on 2024-03-10

3734 Acute, chronic and conditioned effects of intranasal oxytocin in the mu opioid receptor knockout mouse model of autism: social context matters

Pantouli, F.; Pujol, C.; Derieux, C.; Fonteneau, M.; Pellissier, L.; Marsol, C.; Karpenko, J.; Bonnet, D.; Hibert, M.; Bailey, A.; Le Merrer, J.; BECKER, J. A. J.

10.1101/2024.03.07.583912 — animal behavior and cognition — Posted on 2024-03-10

3735 Breaking the rule: An exceptional Y chromosome introgression between deeply divergent primate species

Jensen, A.; Horton, E. R.; Amboko, J.; Parke, S.-A.; Hart, J. A.; Tosi, A.; Guschanski, K.; Detwiler, K. M.

10.1101/2024.03.07.583898 — evolutionary biology — Posted on 2024-03-10

3736 Dynamic energy budget model for a bumble bee colony: Predicting the spatial distribution and dynamics of colonies across multiple seasons

Capera-Aragones, P.; Marino, J.; Hurford, A.; Foxall, E.; C. Tyson, R.

10.1101/2024.03.05.583508 — ecology — Posted on 2024-03-10

3737 CMTM6 maintains B cell intrinsic CD40 expression to regulate anti-tumor immunity

Long, Y.; Chen, R.; Chang, W.; Luo, H.; Li, F.; Sun, J.; Chen, J.; Gong, L.

10.1101/2024.03.05.583639 — immunology — Posted on 2024-03-10

3738 A novel protein Moat prevents ectopic epithelial folding by limiting Bazooka/Par3-dependent adherens junctions

Gu, L.; Sauceda, R.; Brar, J.; Fessahaye, F.; Joo, M.; Lee, J.; Nguyan, J.; Teng, M.; Weng, M.

10.1101/2024.03.05.583570 — developmental biology — Posted on 2024-03-10

3739 Transcriptional dynamics of the murine heart during perinatal development at single-cell resolution

Feulner, L.; Wuennemann, F.; Liang, J.; Hofmann, P.; Hitz, M.-P.; Schapiro, D.; Leclerc, S.; van Vliet, P. P.; Andelfinger, G.

10.1101/2024.03.05.583423 — developmental biology — Posted on 2024-03-10

3740 Effects of Hydrolyzed Collagen as a Dietary Supplement on Fibroblast Activation: A Systematic Review

Inacio, P. A. Q.; Chalupe, F. A.; Vieira, R. P.

10.1101/2024.03.06.583701 — cell biology — Posted on 2024-03-10

3741 A truncation mutant of adenomatous polyposis coli (APC) impairs apical cell extrusion through elevated epithelial tissue tension

Gan, W. J.; Giri, R.; Begun, J.; Abud, H.; Hardeman, E. C.; Gunning, P. W.; Yap, A. S.; Noordstra, I.

10.1101/2024.03.06.583801 — cell biology — Posted on 2024-03-10

3742 Survivin in synergy with BAF/SWI complex binds bivalent chromatin regions and activates DNA damage response in CD4+ T cells

Chandrasekaran, V.; Andersson, K. M. E.; Erlandsson, M. C.; Li, S.; Garcia-Bonete, M.-J.; Malmhall-Bah, E.; Johansson, P.; Katona, G.; Bokarewa, M. I.

10.1101/2024.03.05.583464 — immunology — Posted on 2024-03-10

3743 Sexual Dimorphism in Age-Dependent Neurodegeneration After Mild Head Trauma in Drosophila: Unveiling the Adverse Impact of Female Reproduction

Ye, C.; Ho, R.; Moberg, K.; Zheng, J. Q.

10.1101/2024.03.06.583747 — neuroscience — Posted on 2024-03-10

3744 Cannabinoid CB2 receptors in primary sensory neurons are implicated in CB2 agonist-mediated suppression of paclitaxel-induced neuropathic nociception and sexually-dimorphic sparing of morphine tolerance

Guenther, K. G.; Lin, X.; Xu, Z.; Makriyannis, A.; Romero, J.; Hillard, C.; Mackie, K.; Hohmann, A. G.

10.1101/2024.03.05.583426 — neuroscience — Posted on 2024-03-10

3745 Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies

Sridhar, S.; Vystrcilova, M.; Khani, M. H.; Karamanlis, D.; Schreyer, H. M.; Ramakrishna, V.; Krueppel, S.; Zapp, S. J.; Mietsch, M.; Ecker, A.; Gollisch, T.

10.1101/2024.03.05.583449 — neuroscience — Posted on 2024-03-10

3746 Microglia Depletion leads to Increased Susceptibility to Ocular Hypertension-Dependent Glaucoma

Diemler, C. A.; MacLean, M.; Heuer, S. E.; Wain, A.; Marola, O. J.; LIbby, R. T.; Howell, G.

10.1101/2024.03.05.583529 — neuroscience — Posted on 2024-03-10

3747 Effects of age and dietary methionine restriction on cognitive and behavioural phenotypes in the rTg4510 model of frontotemporal dementia

Souza Matos, M.; Sil, A.; Riedel, G.; Platt, B.; Delibegovic, M.

10.1101/2024.03.05.583295 — neuroscience — Posted on 2024-03-10

3748 Generative interpolation and restoration of images using deep learning for improved 3D tissue mapping

Joshi, S.; Forjaz, A.; Sang Han, K.; Shen, Y.; Xenes, D.; Matelsky, J.; Wester, B.; Munoz-Barrutia, A.; Kiemen, A. L.; Wu, P.-H.; Wirtz, D.

10.1101/2024.03.07.583909 — bioinformatics — Posted on 2024-03-10

3749 Tethering NDC80-NUF2 to microparticles is sufficient to enable their biorientation in the spindle

Asai, K.; Zhou, Y.; Kitajima, T.

10.1101/2024.03.09.582646 — cell biology — Posted on 2024-03-10

3750 A single cell RNA sequence atlas of the early Drosophila larval eye

Raja, K. K. B.; Yeung, K.; Li, Y.; Chen, R.; Mardon, G.

10.1101/2024.03.06.583750 — genomics — Posted on 2024-03-10

3751 Emergence of neural persistence: Insights from computational modelling

Verma, V.

10.1101/2024.02.19.581018 — neuroscience — Posted on 2024-03-10

3752 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion

Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C.

10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-10

3753 FECDO-Flexible and Efficient Coding for DNA Odyssey

Sun, F.; Qian, L.

10.1101/2024.02.18.580107 — bioinformatics — Posted on 2024-03-10

3754 General Capillary Endothelial Cells Undergo Reprogramming into Arterial Endothelial Cells in Pulmonary Hypertension through HIF-2α/Notch4 Pathway

Liu, B.; Yi, D.; Xia, X.; Ramirez, K.; Zhao, H.; Cao, Y.; Tripathi, A.; Dong, R.; Gao, A.; Ding, H.; Qiu, S.; Kalinichenko, V. V.; Fallon, M. B.; Dai, Z.

10.1101/2024.02.13.580227 — physiology — Posted on 2024-03-10

3755 Encompassing view of spatial and single-cell RNA-seq renews the role of the microvasculature in human atherosclerosis

Bleckwehl, T.; Maryam, S.; Babler, A.; Bosteen, M.; Nyberg, M.; Halder, M.; Hvid, H.; Pyke, C.; Voetmann, L. M.; Sluimer, J.; Das, V.; Baumgart, S.; Kramann, R.; Hayat, S.

10.1101/2023.12.15.571796 — bioinformatics — Posted on 2024-03-10

3756 Impaired central pattern generators due to abnormal EPHA4 signaling leads to idiopathic scoliosis

Wang, L.; Zhao, S.; Yang, X.; Zheng, P.; Wen, W.; Xu, K.; Cheng, X.; Li, Q.; Khanshour, A. M.; Koike, Y.; Liu, J.; Fan, X.; Otomo, N.; Chen, Z.; Li, Y.; Li, L.; Xie, H.; Zhu, P.; Li, X.; Niu, Y.; Wang, S.; Liu, S.; Yuan, S.; Terao, C.; Li, Z.; Chen, S.; Zhao, X.; Liu, P.; Posey, J. E.; Wu, Z.; Qiu, G.; Ikegawa, S.; Lupski, J.; Rios, J. J.; Wise, C. A.; Zhang, J.; Zhao, C.; Wu, N.

10.1101/2024.03.04.583361 — genetics — Posted on 2024-03-10

3757 A matter of salt: global assessment of the effect of salt ionic composition as a driver of aquatic bacterial diversity

Szabo, A.; Szekely, A. J.; Boros, E.; Marton, Z.; Csitari, B.; Barteneva, N. S.; Anda, D.; Dobosy, P.; Eiler, A.; Bertilsson, S.; Felfoldi, T.

10.1101/2024.03.09.584225 — microbiology — Posted on 2024-03-10

3758 Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer

De Felice, D.; Alaimo, A.; Bressan, D.; Genovesi, S.; Marmocchi, E.; Annesi, N.; Beccaceci, G.; Dalfovo, D.; Cutrupi, F.; Foletto, V.; Lorenzoni, M.; Gandolfi, F.; Kannan, S.; Verma, C. S.; Vasciaveo, A.; Shen, M. M.; Romanel, A.; Chiacchiera, F.; Cambuli, F.; Lunardi, A.

10.1101/2024.03.06.583256 — cancer biology — Posted on 2024-03-10

3759 Epithelial heme oxygenase-1 enhances colonic tumorigenesis by inhibiting ferroptosis

Callahan, R. C.; Bhagavatula, G.; Curry, J.; Staley, A. W.; Schaefer, R. E. M.; Minhajuddin, F.; Zhou, L.; Neuhart, R.; Atif, S. M.; Orlicky, D. J.; Cartwright, I. M.; Gerich, M.; Theiss, A. L.; Hall, C. H.; Colgan, S. P.; Onyiah, J. C.

10.1101/2024.03.06.583112 — cancer biology — Posted on 2024-03-10

3760 Asynchronous temporal variance in learning behaviour and neural gene expression in a butterfly

Ter, Y. T.; Westerman, E. L.

10.1101/2024.03.07.583937 — animal behavior and cognition — Posted on 2024-03-09

3761 To prosper, live long: understanding the sources of reproductive skew and extreme reproductive success in structured populations

Snyder, R. E.; Ellner, S. P.

10.1101/2024.03.07.583934 — ecology — Posted on 2024-03-09

3762 In vitro and in vivo validation of cwlM and pbpB essentiality for viability and resistance to imipenem in Mycobacterium abscessus

Nuermberger, E. L.; Lee, J. I.; Li, S.-Y.; Rifat, D.; Kurepina, N.; Chen, L.; Kreiswirth, B. N.

10.1101/2024.03.08.584109 — microbiology — Posted on 2024-03-09

3763 An Entrainment Oscillator Mechanism underlies Human Beat Matching Performance

Mondok, C.; Wiener, M.

10.1101/2024.03.07.583955 — neuroscience — Posted on 2024-03-09

3764 On the identification of differentially-active transcription factors from ATAC-seq data

Gerbaldo, F.; Sonder, E.; Fischer, V.; Frei, S.; Wang, J.; Gapp, K.; Robinson, M. D.; Germain, P.-L.

10.1101/2024.03.06.583825 — bioinformatics — Posted on 2024-03-09

3765 Species-specific variation in mitochondrial genome tandem repeat polymorphisms in hares (Lepus spp., Lagomorpha, Leporidae) provides insight into their evolution

Tapanainen, R.; Aasumets, K.; Fekete, Z.; Goffart, S.; Dufour, E.; Pohjoismaki, J. L. O.

10.1101/2024.03.04.583303 — genetics — Posted on 2024-03-09

3766 Non-mechanical disruption of Bacillus subtilis spores allows sensitive and deep characterization of the minimal proteome for resuming a cellular lifestyle.

Huang, Y.; de Koster, A.; Tu, Z.; Gao, X.; Roseboom, W.; Brul, S.; Setlow, P.; Kramer, G.

10.1101/2024.03.08.584050 — microbiology — Posted on 2024-03-09

3767 Novel Polymycoviruses Are Encapsidated in Filamentous Virions

Han, Z.; Jiang, J.; Xu, W.

10.1101/2024.03.08.584110 — microbiology — Posted on 2024-03-09

3768 Proteolytic activity of surface exposed HtrA determines its expression level and is needed to survive acidic conditions in Clostridioides difficile

Corver, J.; Claushuis, B.; Shamorkina, T. M.; de Ru, A. H.; van Leeuwen, M. E.; Hensbergen, P.; Smits, W. K.

10.1101/2024.03.08.584076 — microbiology — Posted on 2024-03-09

3769 Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with reduced kidney function.

Johnson-Martinez, J. P.; Diener, C.; Levine, A. E.; Wilmanski, T.; Suskind, D. L.; Ralevski, A.; Hadlock, J.; Magis, A. T.; Hood, L.; Rappaport, N.; Gibbons, S. M.

10.1101/2023.03.04.531100 — systems biology — Posted on 2024-03-09

3770 Mitochondrial Raf1 Regulates Glutamine Catabolism

Shanderson, R. L.; Ferguson, I. D.; Siprashvili, Z.; Ducoli, L.; Li, A.; Miao, W.; Srinivasan, S.; Velasco, M. G.; Li, Y.; Ye, J.; Khavari, P.

10.1101/2024.03.08.581297 — cancer biology — Posted on 2024-03-09

3771 KPop: Accurate, assembly-free, and scalable comparative analysis of microbial genomes

Didelot, X.; Ribeca, P.

10.1101/2022.06.22.497172 — bioinformatics — Posted on 2024-03-09

3772 Multifaceted Representation of Genes via Deep Learning of Gene Expression Networks

Su, Z.; Fang, M.; Smolnikov, A.; Dinger, M. E.; Oates, E. C.; Vafaee, F.

10.1101/2024.03.07.583777 — bioinformatics — Posted on 2024-03-09

3773 A TLR7 Agonist Conjugated to a Nanofibrous Peptide Hydrogel as a Potent Vaccine Adjuvant

Euliano, E. M.; Pogostin, B. H.; Agrawal, A.; Yu, M. H.; Baryakova, T. H.; Graf, T. P.; Hartgerink, J. D.; McHugh, K. J.

10.1101/2024.03.07.583938 — bioengineering — Posted on 2024-03-09

3774 Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

Salinas-Rebolledo, C.; Blesa, J.; Valenzuela-Nieto, G.; Schwefel, D.; Lopez Gonzalez del Rey, N.; Mendez-Ruette, M.; Burkhalter, J.; Batiz, L. F.; Jara, R.; Obeso, J. A.; Chana-Cuevas, P.; Sapkota, G. P.; Rojas-Fernandez, A.

10.1101/2024.03.08.584142 — biochemistry — Posted on 2024-03-09

3775 Distinct roles of Nrf1 and Nrf2 in coordinately controlling the anti-ageing response

Lyu, D.; Wang, M.; Qiu, L.; Hu, S.; Zhang, Y.

10.1101/2024.03.09.584196 — biochemistry — Posted on 2024-03-09

3776 Cooperative involvement of zipper-interacting protein kinase (ZIPK) and the dual-specificity cell division cycle 14A phosphatase (CDC14A) in vascular smooth muscle cell migration

Al-Ghabkari, A.; Carlson, D. A.; Haystead, T. A.; MacDonald, J. A.

10.1101/2024.03.06.583600 — biochemistry — Posted on 2024-03-09

3777 Effect of pH on the thermostability and redox properties of cytochrome c552 from Wolinella succinogenes

Mordido, V. H.; Carepo, M. S. P.; Cordas, C. M.; Paul, N.; Simon, J.; Moura, I.; Pauleta, S. R.

10.1101/2024.03.09.584216 — biochemistry — Posted on 2024-03-09

3778 Differentiating specific and non-specific protein-metabolite interactions using gradient open port probe electrospray ionization mass spectrometry

Tian, X.; Hopfgartner, G.

10.1101/2024.03.07.583904 — biochemistry — Posted on 2024-03-09

3779 Exploring the mitochondrial genomes and phylogenetic relationships of eleven Bryconidae species

Marquez, E. J.; Gomez-Chavarria, D. A.; Alzate, J. F.

10.1101/2024.03.06.583817 — genetics — Posted on 2024-03-09

3780 MASCOT-Skyline integrates population and migration dynamics to enhance phylogeographic reconstructions

Müller, N. F.; Bouckaert, R. R.; Wu, C.-H.; Bedford, T. F.

10.1101/2024.03.06.583734 — evolutionary biology — Posted on 2024-03-09

3781 Using RNA-targeting CRISPR-Cas13 and engineered U1 systems to reduce ABCA4 splice variants in Stargardt disease

Liu, R. H.-C.; Urrutia-Cabrera, D.; Westin, I. M.; Golovleva, I.; Liu, G.-S.; Kumar, S.; McLenachan, S.; Chen, F. K.; Hsu, F.-T.; Edwards, T.; Martin, K. R.; Cheng, A.; Wong, R. C.

10.1101/2024.03.08.584155 — molecular biology — Posted on 2024-03-09

3782 Protein complex heterogeneity and topology revealed by electron capture charge reduction and surface induced dissociation

Shaw, J.; Harvey, S. R.; Du, C.; Xu, Z.; Olmedillas, E.; Saphire, E. O.; Wysocki, V. H.

10.1101/2024.03.07.583498 — molecular biology — Posted on 2024-03-09

3783 Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex

Maitland, M. E. R.; Onea, G.; Owens, D. D. G.; Gonga-Cave, B. C.; Wang, X.; Arrowsmith, C. H.; Barsyte-Lovejoy, D.; Lajoie, G. A.; Schild-Poulter, C.

10.1101/2024.03.08.584134 — molecular biology — Posted on 2024-03-09

3784 Botrytis cinerea detoxifies the sesquiterpenoid phytoalexin rishitin through multiple metabolizing pathways

Bulasag, A. S.; Ashida, A.; Miura, A.; Pring, S.; Kuroyanagi, T.; Camagna, M.; Tanaka, A.; Sato, I.; Chiba, S.; Ojika, M.; Takemoto, D.

10.1101/2024.03.08.584175 — microbiology — Posted on 2024-03-09

3785 Molecular Mimicry as a Mechanism of Viral Immune Evasion and Autoimmunity

Maguire, C.; Wang, C.; Ramasamy, A.; Fonken, C.; Morse, B.; Lopez, N.; Wylie, D.; Melamed, E.

10.1101/2024.03.08.583134 — microbiology — Posted on 2024-03-09

3786 Analyses of Xenorhabdus griffiniae genomes reveal two distinct sub-species that display intra-species variation due to prophages.

Heppert, J. K.; Awori, R. M.; Cao, M.; Chen, G.; McLeish, J.; Goodrich-Blair, H.

10.1101/2024.03.08.584182 — microbiology — Posted on 2024-03-09

3787 High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains

Loes, A. N.; Tarabi, R. A. L.; Huddleston, J.; Touyon, L.; Wong, S. S.; Cheng, S. M.; Leung, N. H.; Hannon, W. W.; Bedford, T.; Cobey, S.; Cowling, B. J.; Bloom, J. D.

10.1101/2024.03.08.584176 — microbiology — Posted on 2024-03-09

3788 Transcriptional plasticity of virulence genes provides malaria parasites with greateradaptive capacity for avoiding host immunity

Florini, F.; Visone, J. E.; Hadjimichael, E.; Malpotra, S.; Nötzel, C.; Kafsack, B. F. C.; Deitsch, K. W.

10.1101/2024.03.08.584127 — microbiology — Posted on 2024-03-09

3789 Antimicrobial Resistance in Diverse Urban Microbiomes: Uncovering Patterns and Predictive Markers

Toscan, R. B.; Subramanian, B.; Stomma, P.; Łabaj, P. P.; Lesinski, W.; Rudnicki, W.

10.1101/2024.03.08.584116 — microbiology — Posted on 2024-03-09

3790 Culture- and genome-based characterization of a tripartite interaction between patescibacterial epibionts, methylotrophic proteobacteria, and a jumbo phage in freshwater ecosystems

Buderka, F.; Lopez-Garcia, P.; Deschamps, P.; Krupovic, M.; Gutierrez-Preciado, A.; Ciobanu, M.; Bertolino, P.; David, G.; Moreira, D.; Jardillier, L.

10.1101/2024.03.08.584096 — microbiology — Posted on 2024-03-09

3791 Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

Zhang, Z. J.; Cole, C. G.; Coyne, M.; Lin, H.; Dylla, N.; Smith, R. C.; Waligurski, E.; Ramaswamy, R.; Woodson, C.; Burgo, V.; Little, J.; Moran, D.; Rose, A.; McMillin, M.; Mcspadden, E.; Sundararajan, A.; Sidebottom, A.; Pamer, E. G.; Comstock, L. E.

10.1101/2024.03.08.584156 — microbiology — Posted on 2024-03-09

3792 Cryo-EM structure of the bacterial effector protein SipA bound to F-actin reveals a unique mechanism for filament stabilization

Guo, E.; Chou, S. Z.; Lara-Tejero, M.; Galan, J. E.

10.1101/2023.12.21.572903 — microbiology — Posted on 2024-03-09

3793 Convolutional neural network models of the primate retina reveal adaptation to natural stimulus statistics

Vystrcilova, M.; Sridhar, S.; Burg, M. F.; Gollisch, T.; Ecker, A. S.

10.1101/2024.03.06.583740 — neuroscience — Posted on 2024-03-09

3794 A conversion from slow to fast memory in response to passive motion

Javidialsaadi, M.; Albert, S. T.; Wang, J.

10.1101/2021.03.09.434594 — neuroscience — Posted on 2024-03-09

3795 Transient destabilization of whole brain dynamics induced by DMT

Piccinini, J.; Sanz Perl, Y.; Pallavicini, C.; Deco, G.; Kringelbach, M. L.; Nutt, D.; Carhart-Harris, R.; Timmermann, C.; Tagliazucchi, E.

10.1101/2024.01.26.577435 — neuroscience — Posted on 2024-03-09

3796 Understanding flux switching in metabolic networks through an analysis of synthetic lethals

Manojna, S.; Malpani, T.; Mohite, O. S.; Nath, S.; Raman, K.

10.1101/2024.03.05.583461 — systems biology — Posted on 2024-03-09

3797 Highly Dynamic and Sensitive NEMOer Calcium Indicators for Imaging ER Calcium Signals in Excitable Cells

Gu, W.; Chen, J.-H.; Zhang, Y.; Wang, Z.; Li, J.; Wang, S.; Zhang, H.; Jiang, A.; Zhong, Z.; Zhang, J.; Xi, C.; Hou, T.; Gill, D. L.; Li, D.; Mu, Y.; Wang, S.-Q.; Tang, A.-H.; Wang, Y.

10.1101/2024.03.08.583332 — synthetic biology — Posted on 2024-03-09

3798 Unravelling the Interplay of Nitrogen Nutrition and the Botrytis cinerea pectin lyase BcPNL1 in Modulating Arabidopsis thaliana Susceptibility

Daviere, A.; Voxeur, A.; Jolivet, S.; Vernhettes, S.; Soulie, M.-C.; Fagard, M.

10.1101/2024.03.06.583732 — plant biology — Posted on 2024-03-09

3799 Empowering High Throughput Screening of 3D Models: Automated Dispensing of Cervical and Endometrial Cancer Cells

Seymour, S.; Cadena, I.; Johnson, M.; Jenne, M.; Adem, I.; Frankovic, R.; Spence, D.; Haddadin, A.; Fogg, K.

10.1101/2024.03.06.583783 — bioengineering — Posted on 2024-03-09

3800 Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies

Feist, W. N.; Luna, S. E.; Ben-Efraim, K.; Filsinger Interrante, M. V.; Amorin, N. A.; Johnston, N. M.; Bruun, T. U. J.; Ghanim, H. Y.; Lesch, B. J.; Dudek, A. M.; Porteus, M. H.

10.1101/2024.03.08.583956 — bioengineering — Posted on 2024-03-09

3801 Changes of urine proteome after intragastric administration of polysaccharide iron complex in rats

Shen, Z.; Yang, M.; Wang, H.; Gao, Y.

10.1101/2024.03.05.583147 — biochemistry — Posted on 2024-03-09

3802 Multiple Isoforms of the Activin-like receptor Baboon differentially regulate proliferation and conversion behaviors of neuroblasts and neuroepithelial cells in the Drosophila larval brain

Lee, G. G.; Peterson, A. J.; Kim, M.-J.; O'Connor, M. B.; Park, J.

10.1101/2024.03.05.583454 — developmental biology — Posted on 2024-03-09

3803 A low-footprint, fluorescence-based bacterial time-kill assay for estimating dose-dependent cell death dynamics

King, E. S.; Stacey, A. E.; Jacob, S. G.

10.1101/2024.03.08.584154 — microbiology — Posted on 2024-03-09

3804 Engulfment of viable neurons by reactive microglia in prion diseases

Makarava, N.; Safadi, T.; Mychko, O.; Pandit, N. P.; Molesworth, K.; Baiardi, S.; Zhang, L.; Parchi, P.; Baskakov, I. V.

10.1101/2024.03.06.583759 — neuroscience — Posted on 2024-03-09

3805 Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis

Nguyen, B. A.; Singh, V.; Afrin, S.; Singh, P.; Pekala, M.; Ahmed, Y.; Pedretti, R.; Canepa, J.; Lemoff, A.; Kluve-Beckerman, B.; Wydorski, P.; Chhapra, F.; Saelices, L.

10.1101/2024.03.08.582936 — biophysics — Posted on 2024-03-09

3806 Investigation of normalization procedures for transcriptome profiles of compounds oriented toward practical study design

Mizuno, T.; Kusuhara, H.

10.1101/2023.10.01.560398 — bioinformatics — Posted on 2024-03-09

3807 Far-red light increases maize volatile emissions in response to volatile cues from neighboring plants

Escobar-Bravo, R.; Schimmel, B. C.; Zhang, Y.; Wang, L.; Robert, C. A.; Glauser, G.; Ballare, C. L.; Erb, M.

10.1101/2022.09.12.507519 — plant biology — Posted on 2024-03-09

3808 Improved selection of canonical proteins for reference proteomes

Insana, G.; Martin, M. J.; Pearson, W. R.

10.1101/2024.03.04.583387 — bioinformatics — Posted on 2024-03-09

3809 A high throughput assay provides novel insight into type VII secretion in Staphylococcus aureus

Yang, Y.; Scott, A. A.; Kneuper, H.; Alcock, F.; Palmer, T.

10.1101/2023.06.03.543475 — microbiology — Posted on 2024-03-09

3810 Floral scent emission of Epiphyllum oxypetalum: identification of a novel cytosol-localized geraniol biosynthesis pathway

Zhang, Y.; Zhang, Y.; Tian, Q.; Wei, L.; Zhu, T.; Zhou, Z.; Wang, J.; Liu, Z.; Tang, W.; Xiao, H.; Liu, M.; Li, T.; Sun, Q.

10.1101/2023.11.26.568706 — plant biology — Posted on 2024-03-09

3811 Systematic discovery of directional regulatory motifs associated with human insulator sites

Osato, N.; Hamada, M.

10.1101/2024.01.20.573595 — bioinformatics — Posted on 2024-03-09

3812 Improved selection of canonical proteins for reference proteomes

Insana, G.; Martin, M. J.; Pearson, W. R.

10.1101/2024.03.04.583387 — bioinformatics — Posted on 2024-03-09

3813 A metagenomics pipeline reveals insertion sequence-driven evolution of the microbiota

Kirsch, J. M.; Hryckowian, A. J.; Duerkop, B. A.

10.1101/2023.10.06.561241 — genomics — Posted on 2024-03-09

3814 Gelatinous matrix, an original convergent evolution to cope with oligotrophy in Nassellaria (Radiolaria)

Llopis Monferrer, N.; Romac, S.; Laget, M.; Nakamura, Y.; Biard, T.; Sandin, M. M.

10.1101/2024.01.22.576765 — evolutionary biology — Posted on 2024-03-09

3815 The ubiquity of clonal interference in cancer and other range expansions

Stein, A.; Kizhuttil, R.; Bak, M.; Noble, R. J.

10.1101/2023.11.27.568915 — evolutionary biology — Posted on 2024-03-09

3816 Genomic fingerprints of the world's soil ecosystems

Graham, E. B.; Garayburu-Caruso, V. A.; Wu, R.; Zheng, J.; McClure, R.; Jones, G.

10.1101/2023.11.02.563126 — ecology — Posted on 2024-03-09

3817 Dysregulated alveolar epithelial cell progenitor function and identity in Hermansky-Pudlak syndrome pulmonary fibrosis

Wang, J. Y.; Michki, N. S.; Sitaraman, S.; Banaschewski, B. J.; Lin, S. M.; Katzen, J. B.; Basil, M. C.; Cantu, E.; Zepp, J. A.; Frank, D. B.; Young, L. R.

10.1101/2023.06.17.545390 — cell biology — Posted on 2024-03-09

3818 Quantitative Real-Time PCR assays for species-specific detection and quantification of Baltic Sea spring bloom dinoflagellates

Brink, A. M.; Kremp, A.; Gorokhova, E.

10.1101/871020 — molecular biology — Posted on 2024-03-09

3819 Using the pan-genomic framework for the discovery of genomic islands in the haloarchaeon Halorubrum ezzemoulense

Feng, Y.; Arsenault, D.; Louyakis, A. S.; Altman-Price, N.; Gophna, U.; Papke, R. T.; Gogarten, J. P.

10.1101/2023.10.13.561781 — microbiology — Posted on 2024-03-09

3820 A high throughput assay provides novel insight into type VII secretion in Staphylococcus aureus

Yang, Y.; Scott, A. A.; Kneuper, H.; Alcock, F.; Palmer, T.

10.1101/2023.06.03.543475 — microbiology — Posted on 2024-03-09

3821 Cataloging Viral Diversity from Nonaxenic Terrestrial Cyanobacteria Cultures

Ettinger, C. L.; Paul, S. R.; Flores, N.; Ward, R. D.; Pietrasiak, N.; Stajich, J. E.

10.1101/2022.12.14.520320 — microbiology — Posted on 2024-03-09

3822 Blood immunophenotyping identifies distinct kidney histopathology and outcomes in patients with lupus nephritis

Horisberger, A.; Griffith, A.; Keegan, J.; Arazi, A.; Pulford, J.; Murzin, E.; Howard, K.; Hancock, B.; Fava, A.; Sasaki, T.; Ghosh, T.; Inamo, J.; Beuschel, R.; Cao, Y.; Preisinger, K.; Gutierrez-Arcelus, M.; Eisenhaure, T. M.; Guthridge, J.; Hoover, P. J.; Dall'Era, M.; Wofsy, D.; Kamen, D. L.; Kalunian, K. C.; Furie, R.; Belmont, M.; Izmirly, P.; Clancy, R.; Hildeman, D.; Woodle, E. S.; Apruzzese, W.; McMahon, M. A.; Grossman, J.; Barnas, J. L.; Payan-Schober, F.; Ishimori, M.; Weisman, M.; Kretzler, M.; Berthier, C. C.; Hodgin, J. B.; Demeke, D. S.; Putterman, C.; Accelerating Medicines Pa

10.1101/2024.01.14.575609 — immunology — Posted on 2024-03-09

3823 A septo-hypothalamic-medullary circuit directs stress-induced analgesia

Shah, D.; Sharma, P. R.; Agarwal, R.; Barik, A.

10.1101/2023.01.30.526171 — neuroscience — Posted on 2024-03-09

3824 Building a realistic, scalable memory model with independent engrams using a homeostatic mechanism

Kaster, M.; Czappa, F.; Butz-Ostendorf, M.; Wolf, F.

10.1101/2023.08.29.555246 — neuroscience — Posted on 2024-03-09

3825 Trait Reward Sensitivity Modulates Connectivity with the Temporoparietal Junction and Anterior Insula during Strategic Decision Making

Sazhin, D.; Wyngaarden, J. B.; Dennison, J. B.; Zaff, O.; Fareri, D.; McCloskey, M. S.; Alloy, L. B.; Jarcho, J. M.; Smith, D. V.

10.1101/2023.10.19.563125 — neuroscience — Posted on 2024-03-09

3826 Sculpting New Visual Categories into the Human Brain

Iordan, M. C.; Ritvo, V. J. H.; Norman, K. A.; Turk-Browne, N. B.; Cohen, J. D.

10.1101/2020.10.14.339853 — neuroscience — Posted on 2024-03-09

3827 Common neural choice signals emerge artifactually amidst multiple distinct value signals

Froemer, R.; Nassar, M. R.; Ehinger, B. V.; Shenhav, A.

10.1101/2022.08.02.502393 — neuroscience — Posted on 2024-03-09

3828 Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues

Shin, T. W.; Wang, H.; Zhang, C.; An, B.; Lu, Y.; Zhang, E.; Lu, X.; Karagiannis, E.; Kang, J. S.; Emenari, A.; Symvoulidis, P.; Asano, S.; Lin, L.; Costa, E.; IMAXT Grand Challenge Consortium, ; Marblestone, A. H.; Kasthuri, N.; Tsai, L.-H.; Boyden, E.

10.1101/2024.03.07.583776 — neuroscience — Posted on 2024-03-09

3829 A comparison of the parasitoid wasp species richness of tropical forest sites in Peru and Uganda - subfamily Rhyssinae (Hymenoptera: Ichneumonidae)

Hopkins, T.; Tuomisto, H.; Gomez, I. C.; Sääksjärvi, I. E.

10.1101/2023.08.23.554460 — zoology — Posted on 2024-03-09

3830 Black women in medical education publishing: Bibliometric and testimonio accounts using intersectionality methodology

Seide, W.; Maggio, L. A.; Artino, A. R.; Leroux, T. C.; Konopasky, A.

10.1101/2023.08.31.555784 — scientific communication and education — Posted on 2024-03-09

3831 Rendering protein structures inside cells at the atomic level with Unreal Engine

Chen, M.

10.1101/2023.12.08.570879 — scientific communication and education — Posted on 2024-03-09

3832 Spray-induced gene silencing (SIGS) as a tool for the management of Pine Pitch Canker forest disease

Bocos Asenjo, I. T.; Amin, H.; Mosquera, S.; Diez Hermano, S.; Ginesy, M.; Diez, J. J.; Nino Sanchez, J.

10.1101/2024.03.05.583474 — plant biology — Posted on 2024-03-09

3833 GFETM: Genome Foundation-based Embedded Topic Model for scATAC-seq Modeling

Fan, Y.; Li, Y.; Ding, J.; Li, Y.

10.1101/2023.11.09.566403 — bioinformatics — Posted on 2024-03-09

3834 Gene Trajectory Inference for Single-cell Data by Optimal Transport Metrics

Qu, R.; Cheng, X.; Sefik, E.; Stanley, J. S.; Landa, B.; Strino, F.; Platt, S.; Garritano, J.; Odell, I.; Coifman, R.; Flavell, R.; Myung, P.; Kluger, Y.

10.1101/2022.07.08.499404 — bioinformatics — Posted on 2024-03-09

3835 Assessing computational predictions of antimicrobial resistance phenotypes from microbial genomes

Hu, K.; Meyer, F.; Deng, Z.-L.; Asgari, E.; Kuo, T.-H.; Münch, P. C.; McHardy, A. C.

10.1101/2024.01.31.578169 — bioinformatics — Posted on 2024-03-09

3836 ER procollagen storage defect without coupled unfolded protein response drives precocious arthritis

Yammine, K. M.; Abularach, S. M.; Kim, S.-y.; Bikovtseva, A. A.; Lilianty, J.; Butty, V. L.; Schiavoni, R. P.; Bateman, J. F.; Lamande, S. R.; Shoulders, M. D.

10.1101/2023.10.19.562780 — genetics — Posted on 2024-03-09

3837 Developmental trajectories of EEG aperiodic and periodic power: Implications for understanding thalamocortical development during infancy.

Wilkinson, C. L.; Yankowitz, L.; Chao, J. Y.; Gutierrez, R.; Rhoades, J. L.; Shinnar, S.; Purdon, P.; Nelson, C.

10.1101/2023.07.21.550114 — neuroscience — Posted on 2024-03-09

3838 Rule-based modulation of a sensorimotor transformation across cortical areas

Chang, Y.-T.; Finkel, E. A.; Xu, D.; O'Connor, D. H.

10.1101/2023.08.21.554194 — neuroscience — Posted on 2024-03-09

3839 Mono-methylated histones control PARP-1 in chromatin and transcription

Bamgbose, G. G.; Bordet, G.; Lodhi, N.; Tulin, A.

10.1101/2023.11.22.568326 — genetics — Posted on 2024-03-09

3840 A direct experimental test of Ohno's hypothesis

Mihajlovic, L.; Iyengar, B. R.; Baier, F.; Barbier, I.; Iwaszkiewicz, J.; Zoete, V.; Wagner, A.; Schaerli, Y.

10.1101/2023.09.25.559237 — evolutionary biology — Posted on 2024-03-09

3841 Peptidyl-tRNA hydrolysis rate influences the efficiency of nonsense-mediated mRNA decay

Kolakada, D.; Fu, R.; Biziaev, N.; Shuvalov, A.; Lore, M.; Campbell, A. E.; Cortazar, M. A.; Sajek, M. P.; Hesselberth, J. R.; Mukherjee, N.; Alkalaeva, E.; Jagannathan, S.

10.1101/2024.01.10.575080 — molecular biology — Posted on 2024-03-09

3842 The telencephalon is a neuronal substrate for systemic inflammatory responses in teleosts via polyamine metabolism

Mani, A.; Haddad, F.; Barreda, D.; Salinas, I.

10.1101/2024.03.03.583242 — immunology — Posted on 2024-03-09

3843 The structure of an Amyloid Precursor Protein/talin complex indicates a mechanical basis of Alzheimer's Disease.

Ellis, C.; Ward, N. L.; Rice, M.; Ball, N. J.; Lambert, J.-C.; Chapuis, J.; Goult, B. T.

10.1101/2024.03.04.583202 — neuroscience — Posted on 2024-03-09

3844 Predictive Coding Networks for Temporal Prediction

Millidge, B.; Tang, M.; Osanlouy, M.; Harper, N. S.; Bogacz, R.

10.1101/2023.05.15.540906 — neuroscience — Posted on 2024-03-09

3845 Mapping patterns of thought onto brain activity during movie-watching

Wallace, R. S.; Mckeown, B.; Goodall-Halliwell, I.; Chitiz, L.; Forest, P.; Karapanagiotidis, T.; Mulholland, B.; Turnbull, A. G.; Vanderwal, T.; Hardikar, S.; Alam, T. G.; Bernhardt, B.; Wang, H.-T.; Strawson, W.; Milham, M.; Xu, T.; Margulies, D.; Poerio, G. L.; Jefferies, E. S.; Skipper, J. I.; Wammes, J.; Leech, R.; Smallwood, J.

10.1101/2024.01.31.578244 — neuroscience — Posted on 2024-03-09

3846 Specific Modulation of CRISPR Transcriptional Activators through RNA-Sensing Guide RNAs in Mammalian Cells and Zebrafish Embryos

Pelea, O.; Mayes, S.; Ferry, Q. R.; Fulga, T. A.; Sauka-Spengler, T.

10.1101/2023.05.08.539738 — synthetic biology — Posted on 2024-03-09

3847 Live microscopy of multicellular spheroids with the multi-modal near-infrared nanoparticles reveals differences in oxygenation gradients

Debruyne, A. C.; Okkelman, I. A.; Heymans, N.; Pinheiro, C.; Hendrix, A.; Nobis, M.; Borisov, S. M.; Dmitriev, R. I.

10.1101/2023.12.11.571110 — cancer biology — Posted on 2024-03-09

3848 Improved selection of canonical proteins for reference proteomes

Insana, G.; Martin, M. J.; Pearson, W. R.

10.1101/2024.03.04.583387 — bioinformatics — Posted on 2024-03-09

3849 nanoFeatures: a cross-platform application to characterize nanoparticles from super-resolution microscopy images

Izquierdo-Lozano, C.; van Noort, N.; van Veen, S.; Tholen, M. M. E.; Grisoni, F.; Albertazzi, L.

10.1101/2024.02.12.579898 — bioinformatics — Posted on 2024-03-09

3850 Signatures of transposon-mediated genome inflation, host specialization, and photoentrainment in Entomophthora muscae and allied entomophthoralean fungi

Stajich, J. E.; Lovett, B.; Lee, E.; Macias, A. M.; Hajek, A. E.; de Bivort, B. L.; Kasson, M. T.; De Fine Licht, H. H.; Elya, C.

10.1101/2023.09.13.557621 — genomics — Posted on 2024-03-09

3851 Discovering Root Causal Genes with High Throughput Perturbations

Strobl, E. V.; Gamazon, E. R.

10.1101/2024.01.13.574491 — genomics — Posted on 2024-03-09

3852 Landscape structure drives eco-evolution in host-parasite systems.

Deshpande, J. N.; Dakos, V.; Kaltz, O.; Fronhofer, E. A.

10.1101/2023.10.24.563775 — evolutionary biology — Posted on 2024-03-09

3853 Towards reliable detection of introgression in the presence of among-species rate variation

Koppetsch, T.; Malinsky, M.; Matschiner, M.

10.1101/2023.05.21.541635 — evolutionary biology — Posted on 2024-03-09

3854 Mapping the mutational landscape of a full viral proteome reveals distinct profiles of mutation tolerability

Alvarez-Rodriguez, B.; Velandia-Alvarez, S.; Toft, C.; Geller, R.

10.1101/2024.03.07.583990 — microbiology — Posted on 2024-03-09

3855 Prevalence and diversity of TAL effector-like proteins in fungal endosymbiotic Mycetohabitans spp.

Carpenter, S. C. D.; Bogdanove, A. J.; Abbot, B.; Stajich, J. E.; Uehling, J.; Lovett, B.; Kasson, M. T.; Carter, M. E.

10.1101/2023.10.16.562584 — microbiology — Posted on 2024-03-09

3856 Constructing networks for comparison of collagen types

Wesp, V.; Scholz, L.; Ziermann-Canabarro, J. M.; Schuster, S.; Stark, H.

10.1101/2023.08.25.554753 — systems biology — Posted on 2024-03-09

3857 Looming stimuli reliably drive innate, but not learned, defensive responses in rats.

Heinemans, M.; Moita, M. A.

10.1101/2022.02.07.479432 — animal behavior and cognition — Posted on 2024-03-09

3858 Insights on the effect of mega-carcass abundance on the population dynamics of a facultative scavenger predator and its prey

Sidous, M.; Cubaynes, S.; Gimenez, O.; Drouet-Hoguet, N.; Dray, S.; Bollache, L.; Madhlamoto, D.; Ngwenya, N. A.; Fritz, H.; Valeix, M.

10.1101/2023.11.08.566247 — ecology — Posted on 2024-03-09

3859 Engineering an in vitro retinothalamic nerve model

Amos, G.; Ihle, S. J.; Clement, B. F.; Duru, J.; Girardin, S.; Maurer, B.; Delipinar, T.; Varos, J.; Ruff, T.

10.1101/2024.03.06.582645 — neuroscience — Posted on 2024-03-08

3860 Striatal Dopamine Modulates Temporal Surprise P3a

Whitaker, G. A.; Schwartze, M.; Martin, S.; Astudillo, A.; Silverdale, M.; El-Deredy, W.; Kotz, S. A.

10.1101/2024.03.05.583515 — neuroscience — Posted on 2024-03-08

3861 Midbrain Dopaminergic Neuron Development is Regulated by Two Molecularly Distinct Subtypes of Radial Glia Cells

Asgrimsdottir, E. S.; Bassini, L. F.; di Val Cervo, P. R.; Gyllborg, D.; Pastor, C. P.; Lee, K.; Grigsby, C. L.; Islam, S.; Lönnerberg, P.; Villaescusa, C.; Salto, C.; Linnarsson, S.; La Manno, G.; Toledo, E. M.; Arenas, E.

10.1101/2024.03.08.584031 — neuroscience — Posted on 2024-03-08

3862 Blocking Src-PSD-95 interaction rescues glutamatergic signaling dysregulation in schizophrenia.

Featherstone, R.; Li, H.; Sengar, A.; Borgmann-Winter, K. E.; Hahn, C.-G.; Melnychenko, O.; Crown, L. M.; Gifford, R. L.; Amirfathi, F.; Banerjee, A.; Parekh, K.; Heller, M.; Zhang, W.; Marc, A. D.; Salter, M. W.; Siegel, S. J.

10.1101/2024.03.08.584132 — neuroscience — Posted on 2024-03-08

3863 Neurobiological Changes Across Pregnancy: A Longitudinal Investigation

Niu, Y.; Conrad, B. N.; Camacho, M. C.; Ravi, S.; Piersiak, H. A.; Bailes, L. G.; Barnett, W.; Manhard, M. K.; Cole, D. A.; Clayton, E. W.; Osmundson, S. S.; Smith, S. A.; Kujawa, A.; Humphreys, K. L.

10.1101/2024.03.08.584178 — neuroscience — Posted on 2024-03-08

3864 Diffusion kurtosis MRI tracks gray matter myelin content in the primate cerebral cortex

Reveley, C.; Ye, F. Q.; Leopold, D. A.

10.1101/2024.03.08.584058 — neuroscience — Posted on 2024-03-08

3865 Monitoring myelin lipid composition and structure of myelinated fibers reveals a maturation delay in CMT1A

Capodivento, G.; Camera, M.; Liessi, N.; Trada, A.; Debellis, D.; Schenone, A.; Armirotti, A.; Visigalli, D.; Nobbio, L.

10.1101/2024.03.08.581205 — neuroscience — Posted on 2024-03-08

3866 The auditory midbrain mediates tactile vibration sensing

Huey, E. L.; Turecek, J.; Delisle, M. M.; Mazor, O.; Romero, G. E.; Dua, M.; Sarafis, Z. K.; Hobble, A.; Booth, K. T.; Goodrich, L. V.; Corey, D. P.; Ginty, D. D.

10.1101/2024.03.08.584077 — neuroscience — Posted on 2024-03-08

3867 Precision Enhancement of CAR-NK Cells through Non-Viral Engineering and Highly Multiplexed Base Editing

Wang, M.; Krueger, J. B.; Gilkey, A. K.; Stelljes, E. M.; Kluesner, M. G.; Pomeroy, E. J.; Skeate, J. G.; Slipek, N. J.; Lahr, W. S.; Claudio Vazquez, P. N.; Zhao, Y.; Eaton, E. J.; Laoharawee, K.; Webber, B. R.; Moriarity, B. S.

10.1101/2024.03.05.582637 — bioengineering — Posted on 2024-03-08

3868 Spectroscopic assessment of flavor-related chemical compounds in fresh tea shoots using deep learning

Denaro, L. G.; Lin, S.-Y.; Huang, C.-y.

10.1101/2024.03.05.583504 — biochemistry — Posted on 2024-03-08

3869 Regional Plasmodium falciparum subpopulations and malaria transmission connectivity in Africa were detected with an enlarged panel of genome-wide microsatellite loci

Demba, M. A.; Kamau, E.; Raman, J.; Mane, K.; Amenga-Etego, L.; Apinjo, T.; Ishengoma, D. J.; Golassa, L.; Maiga, O.; Ghansa, A.; Bouyou-Akotet, M.; Yavo, W.; Randrianarivelojosia, M.; Diop, F. M.; Oriero, E. C.; Jeffries, D.; D'Alessandro, U.; Djimde, A.; Amambua-Ngwa, A.

10.1101/2024.03.08.584049 — genomics — Posted on 2024-03-08

3870 Molecular insights into the atypical activation mechanism of GPR156 in maintaining auditory function

Ma, X.; Chen, L.-N.; Liao, M.; Zhang, L.; Xi, K.; Guo, J.; Shen, C.; Cai, P.; Shen, Q.; Qi, J.; Zhang, H.; Zang, S.-K.; Dong, Y.-J.; Miao, L.; Qin, J.; Ji, S.-Y.; Li, Y.; Liu, J.; Mao, C.; Zhang, Y.; Chai, R.

10.1101/2024.03.07.581839 — molecular biology — Posted on 2024-03-08

3871 Estrogen deficiency reduces maximal running capacity and affects serotonin levels differently in the hippocampus and nucleus accumbens in response to acute exercise

Lee, E.; Nissinen, T. A.; Yla-Outinen, L.; Jalkanen, A.; Karppinen, J. E.; Vieira-Potter, V.; Lipponen, A.; Karvinen, S.

10.1101/2024.03.05.582269 — molecular biology — Posted on 2024-03-08

3872 Exo70 promotes herpesvirus secretory vesicle tethering and virion release in an exocyst complex-dependent manner

Ma, W.; Xu, Y.; Xie, J.; He, L.; Wang, L.; Yu, J.; Sun, F.; He, D. C.; Wang, H.; He, H.

10.1101/2024.03.08.584044 — microbiology — Posted on 2024-03-08

3873 A comparison between full-length 16S rRNA Oxford Nanopore sequencing and Illumina V3-V4 16S rRNA sequencing in head and neck cancer tissues

Yeo, K.; Connell, J.; Bouras, G.; Smith, E.; Murphy, W.; Hodge, J.-C.; Krishnan, S.; Wormald, P.-J.; Valentine, R.; Psaltis, A.; Vreugde, S.; Fenix, K.

10.1101/2024.03.08.584026 — microbiology — Posted on 2024-03-08

3874 Machine Learning Assisted Spectral Fingerprinting for Immune Cell Phenotyping

Nadeem, A.; Lyons, S.; Kindopp, A.; Jamieson, A.; Roxbury, D.

10.1101/2024.03.05.583608 — immunology — Posted on 2024-03-08

3875 Identification of Druggable Binding Sites and Small Molecules as Modulators of TMC1

De-la-Torre, P.; Martinez-Garcia, C.; Gratias, P.; Mun, M.; Santana, P.; Akyuz, N.; Gonzalez, W.; Indzhykulian, A. A.; Ramirez, D.

10.1101/2024.03.05.583611 — neuroscience — Posted on 2024-03-08

3876 In silico genomic surveillance by CoVerage predicts and characterizes SARS-CoV-2 Variants of Interest

Norwood, K.; Deng, Z.-L.; Reimering, S.; Robertson, G.; Foroughmand-Araabi, M.-H.; Goliaei, S.; Hoelzer, M.; McHardy, A. C.

10.1101/2024.03.07.583829 — bioinformatics — Posted on 2024-03-08

3877 Synth4bench: a framework for generating synthetic genomics data for the evaluation of tumor-only somatic variant calling algorithms

Fragkouli, S.-C.; Pechlivanis, N.; Anastasiadou, A.; Karakatsoulis, G.; Orfanou, A.; Kollia, P.; Agathangelidis, A.; Psomopoulos, F. E.

10.1101/2024.03.07.582313 — bioinformatics — Posted on 2024-03-08

3878 CoupleVAE: coupled variational autoencoders for predicting perturbational single-cell RNA sequencing data

Li, L.; Wu, Y.; Liu, J.; Liu, S.; Xiao, Y.; Zhang, S.

10.1101/2024.03.05.583614 — bioinformatics — Posted on 2024-03-08

3879 Deep Plasma Proteome Profiling by Modulating Single Nanoparticle Protein Corona with Small Molecules

Ashkarran, A. A.; Gharibi, H.; Modaresi, S. M.; Sayadi, M.; Jafari, M.; Lin, Z.; Ritz, D.; Kakhniashvili, D.; Sun, L.; Landry, M. P.; Dibavar, A. S.; Mahmoudi, M.

10.1101/2024.03.06.582595 — bioengineering — Posted on 2024-03-08

3880 Development of a new genotype-phenotype linked antibody screening system

Watanabe, T.; Hata, H.; Mochizuki, Y.; Yokoyama, F.; Hasegawa, T.; Kumar, N.; Kurosaki, T.; Ohara, O.; Fukuyama, H.

10.1101/2024.03.06.581777 — bioengineering — Posted on 2024-03-08

3881 Conformational switch of a peptide provides a novel strategy to design peptide loaded porous organic polymer for Pyroptosis pathway mediated cancer therapy

Chattopahyay, K.; Mishra, S.; Sannigrahi, A.; Ruidas, S.; Chatterjee, S.; Roy, K.; Mishra, D.; Maity, B. K.; Paul, R.; Das Saha, K.; Bhaumik, A.

10.1101/2024.03.05.583621 — biochemistry — Posted on 2024-03-08

3882 Addressing technical pitfalls in pursuit of molecular factors that mediate immunoglobulin gene regulation

Engelbrecht, E. T.; Rodriguez, O. L.; Watson, C. T.

10.1101/2024.03.06.582860 — genomics — Posted on 2024-03-08

3883 HyperGen: Compact and Efficient Genome Sketching using Hyperdimensional Vectors

Xu, W.; Hsu, P.-K.; Moshiri, N.; Yu, S.; Rosing, T.

10.1101/2024.03.05.583605 — genomics — Posted on 2024-03-08

3884 Rapid Degradation of the Human ACE2 Receptor Upon Binding and Internalization of SARS-Cov-2-Spike-RBD Protein

Feinstein, P.

10.1101/2024.03.07.583884 — genetics — Posted on 2024-03-08

3885 Insects visit Fusarium xyrophilum pseudoflowers on the host Xyris surinamensis (Xyridaceae) and carry fungal DNA on their bodies

Cruz, T. J. T.; Cofer, T. M.; Kaminsky, L. M.; Re, L. A.; Vaughn, A.; Johnson, J. R.; Tumlinson, J. H.; Laraba, I.; Proctor, R. H.; Kim, H.-S.; Bell, T. H.; Aime, M. C.; Skvarla, M. J.; Geiser, D. M.

10.1101/2024.03.05.583517 — ecology — Posted on 2024-03-08

3886 JAK-STAT pathway activation compromises nephrocyte function in a Drosophila high-fat diet model of chronic kidney disease

Zhao, Y.; Duan, J.; van de Leemput, J.; Han, Z.

10.1101/2024.03.07.583967 — molecular biology — Posted on 2024-03-08

3887 Fundamental principles of chromosome organization for meiotic recombination

Biot, M.; Toth, A.; Brun, C.; Guichard, L.; de Massy, B.; GREY, C.

10.1101/2024.03.06.583329 — molecular biology — Posted on 2024-03-08

3888 Overexpression of barley heat stress transcription factor HvHsfA6a provide thermotolerance by thermopriming

Chaudhary, R.; Baliyan, S.; Sirohi, P.; Singh, S.; Mishra, S. K.; Rajkumar, M. S.; Saini, S. S.; Germain, H.; Sircar, D.; Chauhan, H.

10.1101/2024.03.06.583688 — molecular biology — Posted on 2024-03-08

3889 Released Bacterial ATP Shapes Local and Systemic Inflammation during Abdominal Sepsis

Spari, D.; Schmid, A.; Sanchez-Taltavull, D.; Murugan, S.; Keller, K.; Ennaciri, N.; Salm, L.; Stroka, D.; Beldi, G.

10.1101/2024.03.07.583973 — microbiology — Posted on 2024-03-08

3890 The role of metals in hypothiocyanite resistance in Escherichia coli

Gray, M. J.

10.1101/2024.03.07.583962 — microbiology — Posted on 2024-03-08

3891 Repeated Binge Alcohol Drinking Leads to Reductions in Corticostriatal Theta Coherence in Female but not Male Mice

Ardinger, C. E.; Lapish, C. C.; Linsenbardt, D. N.

10.1101/2024.03.07.581791 — neuroscience — Posted on 2024-03-08

3892 Highly multiplexed design of an allosteric transcription factor to sense novel ligands

Nishikawa, K. K.; Chen, J.; Acheson, J. F.; Harbaugh, S. V.; Huss, P.; Frenkel, M.; Novy, N.; Sieren, H. R.; Lodewyk, E. C.; Lee, D. H.; Chavez, J. L.; Fox, B. G.; Raman, S.

10.1101/2024.03.07.583947 — synthetic biology — Posted on 2024-03-08

3893 Ratiometric control of two microbial populations in a dual chamber bioreactor

Brancato, S. M.; Salzano, D.; Fiore, D.; Russo, G.; di Bernardo, M.

10.1101/2024.03.08.584056 — synthetic biology — Posted on 2024-03-08

3894 Shear Stress Promotes Remodeling of Platelet Glycosylation via Upregulation of Platelet Glycosidase Activity: The Ulterior Cause of MCS-Related Thrombocytopenia?

Roka-Moiia, Y.; Lewis, S.; Cleveland, E.; Italiano, J. E.; Slepian, M. J.

10.1101/2024.03.05.583630 — biochemistry — Posted on 2024-03-08

3895 Cryo-EM inspired NMR analysis reveals a pH-induced conformational switching mechanism for imparting dynamics to Betanodavirus protrusions

Sterbova, P.; Wang, C.-H.; Carillo, K. J. D.; Lou, Y.-C.; Kato, T.; Namba, K.; Tzou, D.-L. M.; Chang, W.-H.

10.1101/2024.03.08.584019 — biochemistry — Posted on 2024-03-08

3896 Mechanisms mediating arylidene-indolinones induced degradation: thoughts on "Discovery of a Drug-like, Natural Product-Inspired, DCAF11 Ligand Chemotype"

Zhong, C.; Wang, Z.; Li, Z.; Li, H.; Xu, Q.; Wu, W.; Liu, C.; Fei, Y.; Ding, Y.; Lu, B.

10.1101/2024.03.05.582859 — biochemistry — Posted on 2024-03-08

3897 Distinct regions within SAP25 recruit O-linked glycosylation, DNA demethylation, and ubiquitin ligase and hydrolase activities to the Sin3/HDAC complex

Goswami, P.; Banks, C.; Thornton, J.; Bengs, B.; Sardiu, M. E.; Florens, L.; Washburn, M.

10.1101/2024.03.05.583553 — biochemistry — Posted on 2024-03-08

3898 A new type of AmpC β-lactamases defined by PIB-1, a metal-dependent carbapenem-hydrolyzing β-lactamase, from Pseudomonas aeruginosa: structural and functional analysis.

Medrano Martin, F. J.; Hernando-Amado, S.; Martinez, J. L.; Romero, A.

10.1101/2024.03.05.583521 — biochemistry — Posted on 2024-03-08

3899 Large contribution of repeats to genetic variation in a transmission cluster of Mycobacterium tuberculosis

Stritt, C.; Reitsma, M.; Goig, G. A.; Dötsch, A.; Borrell, S.; Beisel, C.; Brites, D.; Gagneux, S.

10.1101/2024.03.08.584093 — genomics — Posted on 2024-03-08

3900 Coronavirus Spike-RBD Variants Differentially Bind to the Human ACE2 Receptor

Feinstein, P.

10.1101/2024.03.07.583944 — genetics — Posted on 2024-03-08

3901 PROTEOME DATA BASED IDENTIFICATION OF POTENTIAL RNAi TARGETS FOR COTTON MEALYBUG (Phenacoccus solenopsis Tinsley) POPULATION MANAGEMENT

SINGH, S.; Rahangdale, S.; PANDITA, S.; SINGH, M.; SAXENA, G.; JAIN, G.; VERMA, P. C.

10.1101/2024.03.08.584030 — molecular biology — Posted on 2024-03-08

3902 PPFlow: Target-aware Peptide Design with Torsional Flow Matching

Lin, H.; Zhang, O.; Zhao, H.; Jiang, D.; Wu, L.; Liu, Z.; Huang, Y.; Li, S. Z.

10.1101/2024.03.07.583831 — molecular biology — Posted on 2024-03-08

3903 Using site-directed mutagenesis to further the understanding of insulin receptor-insulin like growth factor-1 receptor heterodimer structure.

Turvey, S. J.; Muench, S. P.; Issad, T.; Fishwick, C. W.; Kearney, M. T.; Simmons, K. J.

10.1101/2024.03.05.583490 — molecular biology — Posted on 2024-03-08

3904 Comparative analysis of mouse strains for in vivo reprogramming

Pico, S.; Vilchez Acosta, A.; de Sousa, J. A.; Maza, M. d. C.; Parras, A.; Desdin Mico, G.; Mrabti, C.; Yacoub Maroun, C.; Branchina, C.; von Meyenn, F.; Ocampo, A.

10.1101/2024.03.08.584074 — molecular biology — Posted on 2024-03-08

3905 The sulfur-related metabolic status of Aspergillus fumigatus during infection reveals cytosolic serine hydroxymethyltransferase as a promising antifungal target.

Alharthi, R.; Sueiro-Olivares, M.; Storer, I.; Alshammri, H.; Scott, J.; Al-Shidhani, R.; Fortune-Grant, R.; Bignell, E.; Tabernero, L.; Bromley, M.; Zhao, C.; Amich, J.

10.1101/2024.03.08.582945 — microbiology — Posted on 2024-03-08

3906 Unicellular cyanobacteria rely on sodium energetics to fix N2

Tang, S.; Cheng, X.; Liu, Y.; Liu, L.; Liu, D.; Yan, Q.; Zhu, J.; Zhou, J.; Hammerschmidt, K.; Cai, Z.

10.1101/2024.03.08.584021 — microbiology — Posted on 2024-03-08

3907 A tale of two fusion proteins: understanding the metastability of human respiratory syncytial virus and metapneumovirus and implications for rational design of uncleaved prefusion-closed trimers

Lee, Y.-Z.; Han, J.; Zhang, Y.-N.; Ward, G.; Gomes, K. B.; Auclair, S.; Stanfield, R. L.; He, L.; Wilson, I. A.; Zhu, J.

10.1101/2024.03.07.583986 — microbiology — Posted on 2024-03-08

3908 Diverse fox circovirus (Circovirus canine) variants circulate at high prevalence in grey wolves (Canis lupus)

Canuti, M.; King, A. V. L.; Franzo, G.; Cluff, H. D.; Larsen, L. E.; Fenton, H.; Dufour, S. C.; Lang, A. S.

10.1101/2024.03.08.584028 — microbiology — Posted on 2024-03-08

3909 Antigenicity assessment of SARS-CoV-2 saltation variant BA.2.87.1

Yang, S.; Yu, Y.; Jian, F.; Yisimayi, A.; Song, W.; Liu, J.; Wang, P.; Xu, Y.; Wang, J.; Niu, X.; Yu, L.; Wang, Y.; Shao, F.; Jin, R.; Wang, Y.; Cao, Y.

10.1101/2024.03.07.583823 — immunology — Posted on 2024-03-08

3910 Resolution of SARS-CoV-2 infection in human lung tissues is driven by extravascular CD163+ monocytes

Kenney, D. J.; O'Connell, A. K.; Tseng, A. E.; Turcinovic, J.; Sheahan, M. L.; Nitido, A. D.; Montanaro, P.; Gertje, H. P.; Ericsson, M.; Connor, J. H.; Vrbanac, V.; Crossland, N. A.; Harly, C.; Balazs, A. B.; Douam, F.

10.1101/2024.03.08.583965 — immunology — Posted on 2024-03-08

3911 Super-resolution single molecule network analysis (SuperResNET) detects changes to clathrin structure by small molecule inhibitors

Wong, T. H.; Khater, I. M.; Hallgrimson, C.; Li, Y. L.; Hamarneh, G.; Nabi, I. R.

10.1101/2024.03.07.583946 — cell biology — Posted on 2024-03-08

3912 Predictive learning shapes the representational geometry of the human brain

Greco, A.; Moser, J.; Preissl, H.; Siegel, M.

10.1101/2024.03.07.583842 — neuroscience — Posted on 2024-03-08

3913 Lack of TGFβ signaling competency predicts immune poor cancer conversion to immune rich and response to checkpoint blockade

Moore, J.; Gkantalis, J.; Guix, I.; Chou, W.; Yuen, K.; Lazar, A.; Spitzer, M. H.; combes, a.; Barcellos-Hoff, M. H.

10.1101/2024.03.06.583752 — cancer biology — Posted on 2024-03-08

3914 A Dirichlet-multinomial mixed model for determining differential abundance of mutational signatures

Morrill Gavarro, L.; Couturier, D.-L.; Markowetz, F.

10.1101/2024.03.07.583837 — cancer biology — Posted on 2024-03-08

3915 Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues

10.1101/2024.03.07.583776 — bioengineering — Posted on 2024-03-08

3916 Neurophysiological trajectories in Alzheimer's disease progression

Kudo, K.; Ranasinghe, K. G.; Morise, H.; Syed, F.; Sekihara, K.; Rankin, K. P.; Miller, B. L.; Kramer, J.; Rabinovici, G.; Vossel, K.; Kirsch, H. E.; Nagarajan, S.

10.1101/2023.05.18.541379 — neuroscience — Posted on 2024-03-08

3917 Decoding auditory working memory content from EEG aftereffects of auditory-cortical TMS

Uluc, I.; Daneshzand, M.; Jas, M.; Kotlarz, P.; Lankinen, K.; Fiedler, J.; Mamashli, F.; Pajankar, N.; Turpin, T.; Navarro de Lara, L.; Sundaram, P.; Raij, T.; Nummenmaa, A.; Ahveninen, J.

10.1101/2024.03.04.583379 — neuroscience — Posted on 2024-03-08

3918 Robust Methods For Quantifying Neuronal Morphology And Molecular Signaling Reveal That Psychedelics Do Not Induce Neuroplasticity

Boltaev, U.; Park, H. W.; Brown, K. R.; Delgado, M.; Wu, J.; Diaz-Pacheco, B. N.; Botero Pinzon, M.; He, K.; Ahern, E.; Goldshmid, N.; Simpson, E. H.; Sames, D.

10.1101/2024.03.04.583022 — neuroscience — Posted on 2024-03-08

3919 Testing a Method for Quantifying Microplastic Content in Mytilus californianus

Sidhu, A.; Sun, W.; Helal, M.; Gupta, A.; Mittal, A.; Ramanathan, S.; Thakur, M.; Jain, B.; Wang, D.; Benson, A.; Adams, C. T.

10.1101/2024.03.04.583441 — zoology — Posted on 2024-03-08

3920 Glioma-associated fibroblasts promote glioblastoma resistance to temozolomide through CCL2-CCR2 paracrine signaling

Zuo, M.; Zhang, S.; Chen, S.; Xiang, Y.; Yuan, Y.; Li, T.; Yang, W.; Wang, Z.; He, Y.; Li, W.; Feng, W.; Chen, N.; Yang, Y.; Zeng, Y.; Mao, Q.; Chen, M.; Liu, y.

10.1101/2024.03.05.581575 — cancer biology — Posted on 2024-03-08

3921 The EIF4EBP1 gene encoding 4EBP1 is transcriptionally upregulated by MYC and linked to shorter survival in medulloblastoma

Hruby, L.; Scharov, K.; Delaidelli, A.; Picard, D.; Dunham, C.; Lewandowska, O.; Reiff, T.; Larcher, M.; Pouponnot, C.; Sorensen, P. H.; Rotblat, B.; Reifenberger, G.; Remke, M.; Leprivier, G.

10.1101/2024.03.06.583558 — cancer biology — Posted on 2024-03-08

3922 Single-cell analysis of an engineered organoid-based model of pancreatic cancer identifies hypoxia as a contributing factor in the determination of transcriptional subtypes

Landon-Brace, N.; Innes, B. T.; Latour, S.; Cadavid, J. L.; Co, I. L.; Tam, C.; Nowlan, F.; Drissler, S.; Notta, F.; Jackson, H. W.; Bader, G. D.; McGuigan, A. P.

10.1101/2024.03.05.583412 — cancer biology — Posted on 2024-03-08

3923 Lineage commitment pathways epigenetically oppose oncogenic Gαq/11-YAP signaling in dormant disseminated uveal melanoma

Kadamb, R.; Anton, M. L.; Purwin, T. J.; Chua, V.; Seeneevassen, L.; Teh, J.; Nieto, M. A.; Sato, T.; Terai, M.; Roman, S.; de Koning, L.; Zheng, D.; Aplin, A. E.; Aguirre-Ghiso, J.

10.1101/2024.03.05.583565 — cancer biology — Posted on 2024-03-08

3924 A longitudinal single-cell and spatial multiomic atlas of pediatric high-grade glioma

Sussman, J. H.; Oldridge, D. A.; Yu, W.; Chen, C.-H.; Zellmer, A. M.; Rong, J.; Parvaresh-Rizi, A.; Thadi, A.; Xu, J.; Bandyopadhyay, S.; Sun, Y.; Wu, D.; Hunter, C. E.; Brosius, S.; Ahn, K. J.; Baxter, A. E.; Koptyra, M. P.; Vanguri, R.; McGrory, S.; Resnick, A. C.; Storm, P. B.; Amankulor, N. M.; Santi, M.; Viaene, A. N.; Zhang, N.; De Raedt, T.; Cole, K.; Tan, K.

10.1101/2024.03.06.583588 — cancer biology — Posted on 2024-03-08

3925 Post-death Vesicles of Senescent Bone Marrow Mesenchymal Stromal Polyploids Promote Macrophage Aging and Breast Cancer

Xie, B.; Fan, M.; Wang, C. X.; Zhang, Y.; Xu, S.; Mizenko, R.; Lin, T.-y.; Duan, Y.; Zhang, Y.; Huang, J.; Berg, J. I.; Wu, D.; Li, A.; Hao, D.; Gao, K.; Sun, Y.-h.; Tepper, C. G.; Carney, R. P.; Li, Y.; Wang, A.; Gong, Q.; Daly, M.; Jao, L.-E.; Monjazeb, A. M.; Fierro, F. A.; Li, J. J.

10.1101/2024.03.06.583755 — cancer biology — Posted on 2024-03-08

3926 Atypical Cell Cycle Regulation Promotes Mammary Stem Cell Expansion and Therapeutic Resistance

Fifield, B.-A.; Vusich, J.; Haberfellner, E.; Andrechek, E. R.; Porter, L. A.

10.1101/2024.03.05.583524 — cancer biology — Posted on 2024-03-08

3927 Modeling the genomic complexity of human cancer using Cas12a mice

Hebert, J. D.; Xu, H.; Tang, Y. J.; Ruiz, P. A.; Detrick, C.; Wang, J.; Hughes, N. W.; Donosa, O.; Andrejka, L.; Karmakar, S.; Aboiralor, I.; Cong, L.; Sage, J.; Petrov, D.; Winslow, M. M.

10.1101/2024.03.07.583774 — cancer biology — Posted on 2024-03-08

3928 Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis

Hebert, J. D.; Tang, Y. J.; Andrejka, L.; Lopez, S. S.; Petrov, D. A.; Boross, G.; Winslow, M. M.

10.1101/2024.03.07.583981 — cancer biology — Posted on 2024-03-08

3929 De novo detection of somatic variants in long-read single-cell RNA sequencing data

Dondi, A.; Borgsmüller, N.; Ferreira, P. F.; Haas, B. J.; Jacob, F.; Heinzelmann-Schwarz, V.; Tumor Profiler Consortium, ; Beerenwinkel, N.

10.1101/2024.03.06.583775 — cancer biology — Posted on 2024-03-08

3930 Human Cytokine and Coronavirus Nucleocapsid Protein Interactivity Using Large-Scale Virtual Screens

Tomezsko, P. J.; Ford, C. T.; Meyer, A. E.; Michaleas, A. M.; Jaimes, R.

10.1101/2023.11.28.569056 — bioinformatics — Posted on 2024-03-08

3931 Adaptation during the transition from Ophiocordyceps entomopathogen to insect associate is accompanied by gene loss and intensified selection.

Ward, C. M.; Onetto, C. A.; Borneman, A. R.

10.1101/2024.03.04.583259 — genomics — Posted on 2024-03-08

3932 Targeted Long-Read Bisulfite Sequencing for Promoter Methylation Analysis in Severe Preterm Birth

Pereyra, S.; Sardina, A.; Neumann, R.; May, C.; Sapiro, R.; Bertoni, B.; Cappetta, M.

10.1101/2024.03.04.583424 — genetics — Posted on 2024-03-08

3933 Exploration of a European-centered strawberry diversity panel provides markers and candidate genes for the control of fruit quality traits

Prohaska, A.; Rey-Serra, P.; Petit, J.; Petit, A.; Petit, J.; Rothan, C.; Denoyes, B.

10.1101/2024.03.04.583203 — genetics — Posted on 2024-03-08

3934 Sensing of dietary amino acids and regulation of calcium dynamics in adipose tissues through Adipokinetic hormone in Drosophila

Ahmad, M.; Wu, S.; Guo, X.; Perrimon, N.; He, L.

10.1101/2024.03.04.583442 — genetics — Posted on 2024-03-08

3935 Local adaptation of a fungal pathogen to temperature along a latitudinal gradient

Fox, Q. N.; Goodson, C.; Penczykowski, R. M.

10.1101/2024.03.04.583296 — ecology — Posted on 2024-03-08

3936 Rapid UPF1 depletion illuminates the temporal dynamics of the NMD-regulated transcriptome in human cells

Boehm, V.; Wallmeroth, D.; Wulf, P. O.; Alves, L. G. T.; Popp, O.; Riedel, M.; Wyler, E.; Franitza, M.; Gerbracht, J. V.; Becker, K.; Polkovnychenko, K.; Del Giudice, S.; Benlasfer, N.; Mertins, P.; Landthaler, M.; Gehring, N. H.

10.1101/2024.03.04.583328 — molecular biology — Posted on 2024-03-08

3937 GRASPS: a simple-to-operate translatome technology reveals omics-hidden disease-associated pathways in TDP-43-related amyotrophic lateral sclerosis

Lin, Y.-H.; Dodd, J. E.; Cutillo, L.; Castelli, L. M.; Mihaylov, S. R.; Norris, K.; Higginbottom, A.; Walsh, M. J.; Cooper-Knock, J.; Highley, J. R.; Granata, I.; Evans, C. A.; Guarracino, M. R.; Campbell, S. G.; Dickman, M. J.; Shaw, P. J.; Milo, M.; Hautbergue, G. M.

10.1101/2024.03.04.583294 — molecular biology — Posted on 2024-03-08

3938 Tuft cell IL-17RB restrains IL-25 bioavailability and reveals context-dependent ILC2 hypoproliferation

Feng, X.; Andersson, T.; Gschwend, J.; Flüchter, P.; Berest, I.; Muff, J. L.; Carchidi, D.; Lechner, A.; de Tenorio, J. C.; Brander, N.; Boehm, U.; Klose, C. S.; Artis, D.; Leinders-Zufall, T.; Zufall, F.; Schneider, C.

10.1101/2024.03.04.583299 — immunology — Posted on 2024-03-08

3939 Integrated stress response associated with dark microglia promotes microglial lipogenesis and contributes to neurodegeneration

Flury, A.; Aljayousi, L.; Aziz, S.; Park, H.-J.; Khakpour, M.; Sandberg, C.; Ibanez, F. G.; Braniff, O.; Deme, P.; McGrath, J. D.; Ngo, T.; Mechler, J.; Ramirez, D. M.; Avnon-Klein, D.; Murray, J. W.; Liu, J.; Haughey, N. J.; Werneburg, S.; Tremblay, M.-E.; Ayata, P.

10.1101/2024.03.04.582965 — neuroscience — Posted on 2024-03-08

3940 Unbiased estimation of the coefficient of determination in linear models: an application to fMRI encoding model comparison

Lage-Castellanos, A.; De Martino, F.; Valente, G.

10.1101/2024.03.04.583270 — neuroscience — Posted on 2024-03-08

3941 Identification of regional astrocyte heterogeneity associated with cuprizone-induced de- and remyelination using spatial transcriptomics

Miedema, A.; Wijering, M. H. C.; Alsema, A.; Gerrits, E.; Meijer, M.; Koster, M.; Wesseling, E. M.; Baron, W.; Eggen, B. J. L.; Kooistra, S. M.

10.1101/2024.03.04.583308 — neuroscience — Posted on 2024-03-08

3942 Unraveling the Genetic Comorbidity Landscape of Alzheimer's Disease

Zhang, X.; Li, D.; Ye, S.; Liu, S.; Ma, S.; Li, M.; Peng, Q.; Hu, L.; Shang, X.; He, M.; Zhang, L.

10.1101/2024.03.05.583453 — neuroscience — Posted on 2024-03-08

3943 Top-down task goals induce the retrieval state

Smith, D. E.; Long, N. M.

10.1101/2024.03.04.583353 — neuroscience — Posted on 2024-03-08

3944 Selective vulnerability and resilience to Alzheimer's disease tauopathy as a function of genes and the connectome

Anand, C.; Torok, J.; Abdelnour, F.; Maia, P.; Raj, A.

10.1101/2024.03.04.583403 — neuroscience — Posted on 2024-03-08

3945 Assessing the Validity and Reliability of HD-DOT TD-fNIRS Resting-State Measurements in Rapid Succession Data Collection Settings

Oveisi, M. P.; Momi, D.; Morshedzadeh, T.; Bastiaens, S. P.; Griffiths, J. D.

10.1101/2024.03.04.583362 — neuroscience — Posted on 2024-03-08

3946 Sarm1 is not necessary for activation of neuron-intrinsic growth programs yet required for the Schwann cell repair response and peripheral nerve regeneration.

Schmitd, L. B.; Hafner, H.; Ward, A.; Adib, E. A.; Biscola, N. P.; Kohen, R.; Patel, M.; Williamson, R. E.; Desai, E.; Bennett, J.; Saxman, G.; Athaiya, M.; Wilborn, D.; Shumpert, J.; Zhao, X.-F.; Kawaguchi, R.; Geschwind, D. H.; Hoke, A.; Shrager, P.; Collins, C. A.; Havton, L. A.; Kalinski, A. L.; Giger, R. J.

10.1101/2024.03.04.583374 — neuroscience — Posted on 2024-03-08

3947 Network analysis of Marmoset cortical connections reveals pFC and sensory clusters

Pailthorpe, B. A.

10.1101/2024.03.04.582858 — neuroscience — Posted on 2024-03-08

3948 Beyond homogeneity: Charting the landscape of heterogeneity in psychiatric electroencephalography

Ebadi, A.; Allouch, S.; Mheich, A.; Tabbal, J.; Kabbara, A.; Robert, G.; Lefebvre, A.; Iftimovici, A.; Rodriguez-Herreros, B.; Chabane, N.; HASSAN, M.

10.1101/2024.03.04.583393 — neuroscience — Posted on 2024-03-08

3949 Multielectrode array characterization of human induced pluripotent stem cell derived neurons in co-culture with primary human astrocytes.

LeMieux, M. R.; Freigassner, B.; Thathey, Z. A.; Opp, M. R.; Hoeffer, C. A.; Link, C. D.

10.1101/2024.03.04.583341 — neuroscience — Posted on 2024-03-08

3950 Light and dopamine impact two circadian neurons to promote morning wakefulness

Le, J. Q.; Ma, D.; Dai, X.; Rosbash, M.

10.1101/2024.03.04.583333 — neuroscience — Posted on 2024-03-08

3951 Foundations of visual form selectivity for neurons in macaque V1 and V2

Oleskiw, T. D.; Lieber, J. D.; Simoncelli, E. P.; Movshon, J. A.

10.1101/2024.03.04.583307 — neuroscience — Posted on 2024-03-08

3952 Stoichiometric Rays: A simple method to compute the controllable set of enzymatic reaction systems

Himeoka, Y.; Horiguchi, S. A.; Kobayashi, T. J.

10.1101/2024.03.04.583348 — systems biology — Posted on 2024-03-08

3953 Zr-labeled N4MU01 radioimmunoconjugates as theranostics against nectin-4 positive triple negative breast cancer

Babeker, H.; Njotu, F. N.; Ketchemen, J. P.; Tikum, A. F.; Doroudi, A.; Nwangele, E.; Uppalapati, M.; Fonge, H.

10.1101/2024.03.04.583420 — pharmacology and toxicology — Posted on 2024-03-08

3954 Effects of access condition on substance use disorder-like phenotypes in male and female rats self-administering MDPV or cocaine

Doyle, M. R.; Beltran, N. M.; Bushnell, M. S.; Syed, M.; Acosta, V.; Desai, M.; Rice, K. C.; Serafine, K. M.; Gould, G. G.; Daws, L. C.; Collins, G. T.

10.1101/2024.03.04.583431 — pharmacology and toxicology — Posted on 2024-03-08

3955 The Unfolded Protein Response Sensor PERK Mediates Mechanical Stress-induced Maturation of Focal Adhesion Complexes in Glioblastoma Cells

Khoonkari, M.; Liang, D.; Kamperman, M.; van Rijn, P.; Kruyt, F. A.

10.1101/2024.03.04.583281 — cancer biology — Posted on 2024-03-08

3956 Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC

Pomplun, S.; Ellenbroek, B.; Kahler, J. P.; Arella, D.; Lin, C.; Jespers, W.

10.1101/2024.03.04.583305 — cancer biology — Posted on 2024-03-08

3957 An anti-depressant drug vortioxetine suppresses malignant glioblastoma cell growth.

Devare, M. N.; Kaeberlein, M.

10.1101/2024.03.04.583265 — cancer biology — Posted on 2024-03-08

3958 Nociceptive neurons interact directly with gastric cancer cells via a CGRP/Ramp1 axis to promote tumor progression

Zhi, X.; Wu, F.; Qian, J.; Ochiai, Y.; Lian, G.; Malagola, E.; Chen, D.; Ryeom, S. W.; WANG, T. C.

10.1101/2024.03.04.583209 — cancer biology — Posted on 2024-03-08

3959 Role of van der Waals, electrostatic, and hydrogen-bond interactions for the relative stability of cellulose Iβ and II crystals

Kullmann, R.; Delbianco, M.; Roth, C.; Weikl, T. R.

10.1101/2024.03.04.583382 — biophysics — Posted on 2024-03-08

3960 An ab initio information-theoretic approach to proteins and protein-ligand interactions

Nath, D.; Grewal, R. K.; Mitra, D.; Roy, S.

10.1101/2024.03.06.583646 — biophysics — Posted on 2024-03-08

3961 DenoiseST: A dual-channel unsupervised deep learning-based denoising method to identify spatial domains and functionally variable genes in spatial transcriptomics

Cui, Y.; Wang, R.; Zeng, X.; Cui, Y.; Zhu, Z.; Nakai, K.; Ye, X.; Sakurai, T.; Wei, L.

10.1101/2024.03.04.583438 — bioinformatics — Posted on 2024-03-08

3962 SMOC2, OGN, FCN3, and SERPINA3 could be biomarkers for the evaluation of acute decompensated heart failure caused by venous congestion

Yu, Y.; Li, Y.

10.1101/2024.03.04.583279 — bioinformatics — Posted on 2024-03-08

3963 AlGrow: a graphical interface for easy, fast and accurate area and growth analysis of heterogeneously colored targets.

McHale, M.; Sulpice, R.

10.1101/2024.03.04.583395 — bioinformatics — Posted on 2024-03-08

3964 Identification of Potential Therapeutic Targets and Biomarkers for Glioblastomas Through Integrative Analysis of Gene Expression Data

Bautista, A.; Romero, R.

10.1101/2024.03.04.583392 — bioinformatics — Posted on 2024-03-08

3965 Exploring the molecular structure of lipids in the design of artificial lipidated antifungal proteins

Saputra, H.; Safaat, M.; Santoso, P.; Wakabayashi, R.; Goto, M.; Taira, T.; Kamiya, N.

10.1101/2024.03.04.583322 — bioengineering — Posted on 2024-03-08

3966 Changes of urinary proteome in rats after intragastric administration of calcium gluconate

Shen, Z.; Yang, M.; Wang, H.; Gao, Y.

10.1101/2024.03.04.583150 — biochemistry — Posted on 2024-03-08

3967 Client recognition differences between PDI and ERp46 to guide oxidative folding

Saio, T.; Ishii, K.; Matsusaki, M.; Kumeta, H.; Kenemura, S.; Okumura, M.

10.1101/2024.03.04.583432 — biochemistry — Posted on 2024-03-08

3968 Long distance calls: negligible information loss of seabird social vocalisations over propagation down to the hearing threshold

Osiecka, A. N.; Bryndza, P.; Briefer, E. F.; Wojczulanis-Jakubas, K.

10.1101/2024.03.04.583271 — animal behavior and cognition — Posted on 2024-03-08

3969 Unravelling the effects of individual heterogeneity on connectivity estimates: Insights from Spatial Capture-Recapture modelling

Kervellec, M.; Gimenez, O.; Vanpe, C.; Sentilles, J.; Quenette, P.-Y.; Palazon, S.; Afonso Jordana, I.; Jato, R.; Elosegui Irurtia, M. M.; Milleret, C.

10.1101/2024.03.04.583266 — ecology — Posted on 2024-03-08

3970 Food web context modifies predator foraging and weakens trophic interaction strength

Lemmen, K. D.; Pennekamp, F.

10.1101/2024.03.04.583297 — ecology — Posted on 2024-03-08

3971 De Novo TANGLED1 Recruitment to Aberrant Cell Plate Fusion Sites in Maize

Uyehara, A. N.; Diep, B. N.; Allsman, L. A.; Gayer, S. G.; Martinez, S. E.; Kim, J. J.; Agarwal, S.; Rasmussen, C.

10.1101/2024.03.07.583939 — plant biology — Posted on 2024-03-08

3972 WITHDRAWN: Assessment of Remediation Through Measuring Nuclear Respiratory Factor 1 (nrf1) Environmental Stressor Transcriptomic Gene Signatures

Morales, J. C.; Deoraj, A.; Felty, Q.; Lagos, L.; Yoo, C.; Roy, D.

10.1101/2024.02.21.581481 — genomics — Posted on 2024-03-08

3973 DNA binding site II is required for RAD51 recombinogenic activity in Arabidopsis thaliana

Petiot, V.; White, C. I.; Da Ines, O.

10.1101/2024.03.07.583932 — genetics — Posted on 2024-03-08

3974 Differential CheR affinity for chemoreceptor C-terminal pentapeptides biases chemotactic responses

Velando, F.; Monteagudo-Cascales, E.; Matilla, M. A.; Krell, T.

10.1101/2024.03.07.583918 — microbiology — Posted on 2024-03-08

3975 Frequency-specific cortico-subcortical interaction in continuous speaking and listening

Abbasi, O.; Steingräber, N.; Chalas, N.; Kluger, D. S.; Gross, J.

10.1101/2024.03.05.583572 — neuroscience — Posted on 2024-03-08

3976 k-Means NANI: an improved clustering algorithm for Molecular Dynamics simulations

Chen, L.; Roe, D. R.; Kochert, M.; Simmerling, C.; Miranda Quintana, R. A.

10.1101/2024.03.07.583975 — biophysics — Posted on 2024-03-08

3977 GelBox: Open-source software to improve rigor and reproducibility when analyzing gels and immunoblots

Gulbulak, U.; Wellette-Hunsucker, A. G.; Campbell, K.

10.1101/2024.03.07.583941 — biochemistry — Posted on 2024-03-08

3978 Detection of idiosyncratic gaze fingerprint signatures in humans

Crockford, S. K.; Satta, E.; Severino, I.; Fiacchino, D.; Vitale, A.; Bertelsen, N.; Busuoli, E. M.; Mandelli, V.; Lombardo, M. V.

10.1101/2023.09.18.558217 — neuroscience — Posted on 2024-03-08

3979 CLOCK evolved in cnidaria to synchronize internal rhythms with diel environmental cues

Aguillon, R.; Rinsky, M.; Simon-Blecher, N.; Doniger, T.; Appelbaum, L.; Levy, O.

10.1101/2023.03.30.534918 — evolutionary biology — Posted on 2024-03-08

3980 Composition can buffer protein dynamics within liquid-like condensates.

Jelenic, S.; Bindics, J.; Czermak, P.; Pillai, B. R.; Ruer, M.; Hoege, C.; Holehouse, A. S.; Saha, S.

10.1101/2022.05.16.492059 — cell biology — Posted on 2024-03-08

3981 Field size as a predictor of "excellence." The selection of subject fields in Germany's Excellence Initiative.

Heinze, T.; Habicht, I. M.; Eberhardt, P.; Tunger, D.

10.1101/2024.03.06.583816 — scientific communication and education — Posted on 2024-03-08

3982 Learn!Bio - A time-limited cross-sectional study on biosciences students' pathway to resilience during and post the Covid-19 pandemic at an UK university from 2020-2023 and insights into future teaching approaches.

Andrews, K.; Stoneley, R.; Eckl, K.

10.1101/2024.03.06.583815 — scientific communication and education — Posted on 2024-03-08

3983 Leucine Rich Repeat Kinase 2 is not required for lysozyme expression in intestinal Paneth cells

Tasegian, A.; Dikovskaya, D.; Scott, M.; Helps, T.; Meus, T.; McLean, M. H.; Swamy, M.

10.1101/2024.03.07.582590 — physiology — Posted on 2024-03-08

3984 Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis

Veloso, A.; Slegers, T.; Schoenaker, J.; Demeyer, S.; Van den Bergh, S.; Aertgeerts, M.; Verhoeft, K.; Schoenmaekers, Y.; Meeuws, N.; Bischops, I.; Renard, F.; Boogaerts, L.; Mentens, N.; Gielen, O.; Jacobs, K.; Segers, H.; Cools, J.; Dierickx, D.; Vanden Bempt, M.

10.1101/2024.03.03.583195 — cancer biology — Posted on 2024-03-08

3985 N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine

Wang, C.; Zhao, C.; Xiao, H.; Qiang, J.; Liu, Z.; Gu, J.; Zhang, S.; Li, D.; Zhang, Y.; Burre, J.; Diao, J.; Liu, C.

10.1101/2024.03.04.583437 — biophysics — Posted on 2024-03-08

3986 Diabetes induces differences in costameric proteins and increases cardiomyocyte stiffness

Romanelli, G.; Villarreal, L.; Espasandin, C.; Benech, J. C.

10.1101/2024.03.05.583628 — cell biology — Posted on 2024-03-08

3987 Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/beta-catenin signaling

Ntourmas, S.; Sachs, M.; Bruckner, M.; Behrens, J.; Bernkopf, D. B.

10.1101/2024.03.07.583872 — cell biology — Posted on 2024-03-08

3988 Feedback modulation of Orai1α and Orai1β protein content mediated by STIM proteins

Nieto-Felipe, J.; Macias-Diaz, A.; Jimenez-Velarde, V.; Lopez, J. J.; Salido, G. M.; Smani, T.; Jardin, I.; Rosado, J. A.

10.1101/2024.03.05.583469 — cell biology — Posted on 2024-03-08

3989 SUN2 mediates calcium-triggered nuclear actin polymerization to cluster active RNA polymerase II

Grosse, R.; Ulferts, S.

10.1101/2024.03.04.583287 — cell biology — Posted on 2024-03-08

3990 High-content high-resolution microscopy and deep learning assisted analysis reveals host and bacterial heterogeneity during Shigella infection

Lopez-Jimenez, A. T.; Brokatzky, D.; Pillay, K.; Williams, T.; Özbaykal Güler, G.; Mostowy, S.

10.1101/2024.03.06.583762 — cell biology — Posted on 2024-03-08

3991 Synphilin-1 as a modulator of aSyn assembly

Lazaro, D.; Amen, T.; Gerhardt, E.; dos Santos, P. P.; Milovanovic, D.; Höglinger, G.; Outeiro, T.

10.1101/2024.03.05.583522 — molecular biology — Posted on 2024-03-08

3992 Antigenic determinants of HAstV-VA1 neutralization and their relevance in the human immune response

Ramirez-Bello, I.; Lopez, T.; Espinosa, R.; Ghosh, A.; Green, K.; Riano-Umbarila, L.; Gaspar-Castillo, C.; Alpuche-Aranda, C.; Lopez, S.; DuBois, R. M.; Arias, C. F.

10.1101/2024.03.05.583477 — microbiology — Posted on 2024-03-08

3993 Sanctuary: A Starship transposon facilitating the movement of the virulence factor ToxA in fungal wheat pathogens

Bucknell, A.; Wilson, H.; Goncalves dos Santos, K. C.; Simpfendorfer, S.; Milgate, A.; Germain, H.; Solomon, P.; Bentham, A.; McDonald, M.

10.1101/2024.03.04.583430 — genomics — Posted on 2024-03-08

3994 The role of cognition and movement of seed-dispersing animals in shaping plant distributions

Robira, B.

10.1101/2023.08.01.551244 — ecology — Posted on 2024-03-08

3995 Heterogeneous identity, stiffness and growth characterise the shoot apex of Arabidopsis stem cell mutants

Rambaud-Lavigne, L.; Chatterjee, A.; Bovio, S.; Battu, V.; Lavigne, Q.; Gundiah, N.; Boudaoud, A.; Das, P.

10.1101/2023.07.28.550972 — plant biology — Posted on 2024-03-08

3996 Detecting phenotype-specific tumor microenvironment by merging bulk and single cell expression data to spatial transcriptomics

Zhu, W.; Tang, H.; Zeng, T.

10.1101/2024.02.23.581547 — bioinformatics — Posted on 2024-03-08

3997 Advancing Drug-Target Interactions Prediction: Leveraging a Large-Scale Dataset with a Rapid and Robust Chemogenomic Algorithm.

Guichaoua, G.; Pinel, P.; Hoffmann, B.; Azencott, C.-A.; Stoven, V.

10.1101/2024.02.22.581599 — bioinformatics — Posted on 2024-03-08

3998 Deciphering Peptide-Protein Interactions via Composition-Based Prediction: A Case Study with Survivin/BIRC5

Anindya, A. L.; Olsson, T. N.; Jensen, M.; Garcia-Bonete, M.-J.; Wheatley, S.; Bokarewa, M. I.; Mezzasalma, S. A.; Katona, G.

10.1101/2024.02.12.579763 — bioinformatics — Posted on 2024-03-08

3999 Thermal tolerance traits of individual corals are widely distributed across the Great Barrier Reef

DENIS, H.; Bay, L. K.; Mocellin, V. J. L.; Naugle, M. S.; Lecellier, G.; Purcell, S. W.; Berteaux-Lecellier, V.; Howells, E. J.

10.1101/2024.01.28.576773 — ecology — Posted on 2024-03-08

4000 Discovery of a pentose as a cytosine nucleobase modification in Shewanella phage Thanatos-1 genomic DNA mediating enhanced resistance towards host restriction systems

Brandt, D.; Dorrich, A. K.; Persicke, M.; Leonhard, T.; Haak, M.; Nolting, S.; Ruwe, M.; Schmid, N. E.; Thormann, K.; Kalinowski, J.

10.1101/2024.02.27.582347 — molecular biology — Posted on 2024-03-08

4001 Social interactions are impacted by food availability, food type, and group size

Guo, X.; Hasenjager, M.; Fefferman, N.; Pinter-Wollman, N.

10.1101/2024.03.07.584014 — animal behavior and cognition — Posted on 2024-03-07

4002 Motivational modulation of flight speed in foraging bumblebees

Willemet, R.

10.1101/2024.03.06.583792 — animal behavior and cognition — Posted on 2024-03-07

4003 A Human Brain Map of Mitochondrial Respiratory Capacity and Diversity

Mosharov, E.; Rosenberg, A. M.; Monzel, A. S.; Osto, C. A.; Stiles, L.; Rosoklija, G. B.; Dwork, A. J.; Bindra, S.; Zhang, Y.; Fujita, M.; Mariani, M. B.; Bakalian, M.; Sulzer, D.; De Jager, P.; Menon, V.; Shirihai, O. S.; Mann, J.; Underwood, M.; Boldrini, M.; Thiebaut de Schotten, M. S.; Picard, M.

10.1101/2024.03.05.583623 — neuroscience — Posted on 2024-03-07

4004 Celsr3 drives development and connectivity of the acoustic startle hindbrain circuit

Meserve, J. H.; Navarro, M. F.; Ortiz, E. A.; Granato, M.

10.1101/2024.03.07.583806 — neuroscience — Posted on 2024-03-07

4005 Computation or Weight Adaptation? Rethinking the Role of Plasticity in Learning

Lior, G.; Shalev, Y.; Stanovsky, G.; Goldstein, A.

10.1101/2024.03.07.583890 — neuroscience — Posted on 2024-03-07

4006 Unraveling the Role of MIXL1 Activation in Endoderm Differentiation of Isogenic Human Induced Pluripotent Stem Cells

Osteil, P.; Withey, S.; Santucci, N.; Aryamanesh, N.; Pang, C. N. I.; Salehin, N.; Sun, J.; Qin, A.; Su, J.; Knowles, H.; Cai, Z.; Craft, G.; Graham, M. E.; Li, X. B.; Wolvetang, E. J.; Tam, P. P. L.

10.1101/2024.03.06.583475 — developmental biology — Posted on 2024-03-07

4007 Thermodynamically-consistent, reduced models of gene regulatory networks

Pan, M.; Gawthrop, P. J.; Faria, M.; Johnston, S. T.

10.1101/2023.11.13.566770 — synthetic biology — Posted on 2024-03-07

4008 Epstein-Barr Virus Orchestrates Spatial Reorganization and Immunomodulation within the Classic Hodgkin Lymphoma Tumor Microenvironment

Yeo, Y. Y.; Qiu, H.; Bai, Y.; Zhu, B.; Chang, Y.; Yeung, J.; Michel, H. A.; Wright, K. T.; Shaban, M.; Sadigh, S.; Nkosi, D.; Shanmugam, V.; Yiu, S. P. T.; Cramer, P.; Rock, P.; Paczkowska, J.; Stephan, P.; Liao, G.; Wang, H.; Huang, A. Y.; Chen, H.; Frauenfeld, L.; Mitra, B.; Gewurz, B. E.; Schurch, C. M.; Zhao, B.; Nolan, G. P.; Zhang, B.; Shalek, A. K.; Angelo, M.; Mahmood, F.; Ma, Q.; Burack, W. R.; Shipp, M. A.; Rodig, S. J.; Jiang, S.

10.1101/2024.03.05.583586 — cancer biology — Posted on 2024-03-07

4009 Signaling events at TMEM doorways provide potential targets for inhibiting breast cancer dissemination

Surve, C. R.; Duran, C. L.; Ye, X.; Chen, X.; Lin, Y.; Harney, A. S.; Wang, Y.; Sharma, V. P.; Stanley, E. R.; Cox, D.; McAuliffe, J. C.; Entenberg, D.; Oktay, M. H.; Condeelis, J. S.

10.1101/2024.01.08.574676 — cancer biology — Posted on 2024-03-07

4010 Mitotic waves in frog egg extracts: Transition from phase waves to trigger waves

Puls, O.; Ruiz-Reynes, D.; Tavella, F.; Jin, M.; Kim, Y.; Gelens, L.; Yang, Q.

10.1101/2024.01.18.576267 — biophysics — Posted on 2024-03-07

4011 GP-HTNLoc: A Graph Prototype Head-Tail Network-based Model for Multi-label Subcellular Localization Prediction of ncRNAs

Han, S.; Liu, L.

10.1101/2024.03.04.583439 — bioinformatics — Posted on 2024-03-07

4012 A Foundation Model for Cell Segmentation

Israel, U.; Marks, M.; Dilip, R.; Li, Q.; Yu, C.; Laubscher, E.; Li, S.; Schwartz, M. S.; Pradhan, E.; Ates, A.; Abt, M.; Brown, C.; Pao, E.; Pearson-Goulart, A.; Perona, P.; Gkioxari, G.; Barnowski, R.; Yue, Y.; Van Valen, D. A.

10.1101/2023.11.17.567630 — bioinformatics — Posted on 2024-03-07

4013 Shear Stress Induces a Pro-Inflammatory Phenotype in Human Monocyte-Derived Macrophages

Jui, E.; Kingsley, G.; Pham, H. K.; Singampalli, K.; Birla, R.; Connell, J.; Keswani, S.; Grande-Allen, K. J.

10.1101/2022.12.08.519590 — bioengineering — Posted on 2024-03-07

4014 Behavioral sequences across multiple animal species in the wild share common structural features

Minasandra, P.; Grout, E. M.; Brock, K.; Crofoot, M. C.; Demartsev, V.; Gersick, A. S.; Hirsch, B. T.; Holekamp, K. E.; Johnson-Ulrich, L.; Nayak, A.; Ortega, J.; Roch, M. A.; Strauss, E. D.; Strandburg-Peshkin, A.

10.1101/2024.01.20.576411 — animal behavior and cognition — Posted on 2024-03-07

4015 Unifying approaches from statistical genetics and phylogenetics for mapping phenotypes in structured populations

Schraiber, J. G.; Edge, M. D.; Pennell, M.

10.1101/2024.02.10.579721 — genomics — Posted on 2024-03-07

4016 Transposable elements impact the population divergence of rice blast fungus Magnaporthe oryzae

Lin, L.; Sun, T.; Guo, J.; Lin, L.; Chen, M.; Wang, Z.; Bao, J.-D.; Norvienyeku, J.; Han, Y.; Lu, G.; Rensing, C.; Zheng, H.; Zhong, Z.; Wang, Z.

10.1101/2023.05.12.540556 — evolutionary biology — Posted on 2024-03-07

4017 Amoeboid cells undergo durotaxis with soft end polarized NMIIA

Kang, C.; Chen, P.; Yi, X.; Li, D.; Hu, Y.; Yang, Y.; Cai, H.; Li, B.; Wu, C.

10.1101/2023.04.13.536664 — cell biology — Posted on 2024-03-07

4018 Subnanometer structure of medusavirus capsid during maturation using cryo-electron microscopy

Watanabe, R.; Song, C.; Takemura, M.; Murata, K.

10.1101/2024.03.07.583866 — molecular biology — Posted on 2024-03-07

4019 Dendritic voltage imaging maps the biophysical basis of plateau potentials in the hippocampus

Park, P.; Wong-Campos, J. D.; Itkis, D.; Lee, B. H.; Qi, Y.; Davis, H. C.; Grimm, J. B.; Plutkis, S. E.; Lavis, L.; Cohen, A. E.

10.1101/2023.06.02.543490 — neuroscience — Posted on 2024-03-07

4020 Spatial attention alters visual cortical representation during target anticipation

Tüncok, E.; Carrasco, M.; Winawer, J.

10.1101/2024.03.02.583127 — neuroscience — Posted on 2024-03-07

4021 Serotonergic amplification of odor-evoked neural responses maps flexibly onto behavioral outcomes

Bessonova, Y.; Raman, B.

10.1101/2023.08.08.552516 — neuroscience — Posted on 2024-03-07

4022 Visualization of endogenous G proteins on endosomes and other organelles

Jang, W.; Senarath, K.; Lu, S.; Lambert, N. A.

10.1101/2024.03.05.583500 — pharmacology and toxicology — Posted on 2024-03-07

4023 Biochemical properties of chromatin domains define genome compartmentalization

Lucini, F.; Petrini, C.; Salviato, E.; Pal, K.; Rosti, V.; Gorini, F.; Santarelli, P.; Quadri, R.; Lembo, G.; Graziano, G.; Di Patrizio Soldateschi, E.; Tagliaferri, I.; Pinatel, E.; Sebestyen, E.; Rotta, L.; Gentile, F.; Vaira, V.; Lanzuolo, C.; Ferrari, F.

10.1101/2024.03.05.583467 — genomics — Posted on 2024-03-07

4024 Adaptive admixture at ACKR1 (the Duffy locus) may have shaped Plasmodium vivax prevalence in Oman

Haffener, P. E.; Al-Riyami, A. Z.; Al-Zadjali, S.; Busby, G. B. J.; Al Mahdhuri, S.; Al-Rawahi, M.; Al Hosni, S.; Al Marhoobi, A.; Al Sheriyani, A.; Leffler, E. M.

10.1101/2024.03.06.583766 — genetics — Posted on 2024-03-07

4025 Species-specific variation in mitochondrial genome tandem repeat polymorphisms in hares (Lepus spp., Lagomorpha, Leporidae) provides insight into their evolution

Tapanainen, R.; Aasumets, K.; Fekete, Z.; Goffart, S.; Dufour, E.; Pohjoismaki, J. L. O.

10.1101/2024.03.04.583303 — genetics — Posted on 2024-03-07

4026 Fine-scale oceanographic processes shape marine biodiversity patterns in the Galapagos Islands

Holman, L. E.; Pazmino, D. A.; Gopalakrishnan, S.; Forryan, A.; Hearn, A. R.; Naveira-Garabato, A. C.; Rius, M.

10.1101/2024.03.06.583537 — ecology — Posted on 2024-03-07

4027 Disentangling the multiple drivers of ecological adaptation in a microorganism

Perna, A.; Rivoli, E. S.; Perkins, D. M.

10.1101/2023.07.25.550219 — ecology — Posted on 2024-03-07

4028 EDC-3 and EDC-4 Regulate Embryonic mRNA Clearance and Biomolecular Condensate Specialization

Vidya, E.; Jami-Alahmadi, Y.; Mayank, A. K.; Rizwan, J.; Xu, J. M. S.; Cheng, T.; Leventis, R.; Sonenberg, N.; Wohlschlegel, J.; Vera, M.; Duchaine, T.

10.1101/2024.03.04.583404 — molecular biology — Posted on 2024-03-07

4029 Temporal Microbiome Changes in Axolotl Limb Regeneration: Stage-Specific Restructuring of Bacterial and Fungal Communities with a Flavobacterium Bloom During Blastema Proliferation

Altin, H. K.; Delice, B.; Yildirim, B.; Demircan, T.; Yildirim, S.

10.1101/2024.03.07.583834 — microbiology — Posted on 2024-03-07

4030 FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling

Khan, M. S. H.; Kim, S. Q.; Ross, R. C.; Corpodean, F.; Span, R. A.; Albarado, D. A.; Fernandez-Kim, S. O.; Clarke, B.; Berthoud, H.-R.; Münzberg, H.; Albaugh, V. L.; Soto, P.; Morrison, C. D.

10.1101/2024.03.05.583399 — neuroscience — Posted on 2024-03-07

4031 Visualizing the Spatio-Temporal Dynamics of Clonal Evolution with LinG3D software

Hu, A.; Ojwang, A. M.; Olumoyin, K. D.; Rejniak, K. A.

10.1101/2024.03.05.583631 — systems biology — Posted on 2024-03-07

4032 Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis.

Verma, S.; Giagnocavo, S. D.; Curtin, M. C.; Arumugam, M.; Osburn-Staker, S. M.; Wang, G.; Atkinson, A.; Nix, D. A.; Lum, D. H.; Cox, J. E.; Hilgendorf, K. I.

10.1101/2024.03.04.583349 — cancer biology — Posted on 2024-03-07

4033 Designing Combinatorial Multiepitope Vaccine Candidates against Scrub Typus by a Proteome-wide Immunoinfomatics Approach.

Shaw, S.; Bagchi, A.; Ruj, D.; Bhattacharya, S. P.; Biswas, A.; Bhattacharya, A.

10.1101/2024.03.05.583536 — bioinformatics — Posted on 2024-03-07

4034 Long-read sequencing and genome assembly of natural history collection samples and challenging specimens

Bein, B.; Chrysostomakis, I.; Arantes, L.; Brown, T.; Gerheim, C.; Schell, T.; Schneider, C.; Leushkin, E.; Chen, Z.; Sigwart, J.; Gonzalez, V.; Wong, L.; Santos, F.; Blom, M.; Mayer, F.; Mazzoni, C.; Boehne, A.; Winkler, S.; Greve, C.; Hiller, M.

10.1101/2024.03.04.583385 — genomics — Posted on 2024-03-07

4035 Population genetics and phylogeographic history of the insular lizard Podarcis lilfordi (Gunther, 1874) from the Balearic Islands based on genome-wide polymorphic data

Otalora Acevedo, K. E.; Riera Rey, J. L.; Tavecchia, G.; Rotger, A.; Igual, J. M.; Trotta, J.-R.; Baldo, L.

10.1101/2024.03.06.583662 — genomics — Posted on 2024-03-07

4036 Impacts of yeast Tma20/MCTS1, Tma22/DENR and Tma64/eIF2D on translation reinitiation and ribosome recycling

Jendruchov, K.; Gaikwad, S.; Poncova, K.; Gunisova, S.; Valasek, L. S.; Hinnebusch, A. G.

10.1101/2024.03.06.583729 — genetics — Posted on 2024-03-07

4037 RPA and Rad27 limit templated and inverted insertions at DNA breaks

Ira, G.; Yu, Y.; Chen, K.; Wang, X.; Fox, J.; Hastings, P. J.; Yu, Y.; Li, Q.

10.1101/2024.03.07.583931 — genetics — Posted on 2024-03-07

4038 Proteogenomic analysis reveals adaptive strategies to alleviate the consequences of aneuploidy in cancer

Boekenkamp, J.-E.; Keuper, K.; Redel, S.; Barthel, K.; Johnson, L.; Wieland, A.; Raschle, M.; Storchova, Z.

10.1101/2024.03.05.583460 — genetics — Posted on 2024-03-07

4039 Antisense transcription can induce expression memory via stable promoter repression

Mutzel, V.; Schwämmle, T.; Oeverdieck, S.; Librenjak, L.; Boesen, B.; Bothe, M.; Gjaltema, R. A.; Dunkel, I.; Noviello, G.; Schulz, E. G.

10.1101/2024.03.06.583761 — genetics — Posted on 2024-03-07

4040 Light as an "ecological trap". A synanthropic incipient speciation taken up by the gecko

Fulgione, D.; Maselli, V.; Avallone, B.; Rivieccio, E.; Mondanaro, A.; Giurato, G.; Buglione, M.

10.1101/2024.03.05.583480 — evolutionary biology — Posted on 2024-03-07

4041 PRDM9 drives the location and rapid evolution of recombination hotspots in salmonids

Raynaud, M.; Sanna, P.; Joseph, J.; Clement, J.; Imai, Y.; Lareyre, J.-J.; Laurent, A.; Galtier, N.; Baudat, F.; Duret, L.; Gagnaire, P.-A.; de Massy, B.

10.1101/2024.03.06.583651 — evolutionary biology — Posted on 2024-03-07

4042 Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology

Mummah, R. O.; Gomez, A. C. R.; Guglielmino, A. H.; Borremans, B.; Galloway, R. L.; Prager, K. C.; Lloyd-Smith, J. O.

10.1101/2024.03.05.583452 — ecology — Posted on 2024-03-07

4043 Pawpaws prevent predictability: A locally-dominant tree alters understory beta-diversity and community assembly

Wassel, A.; Myers, J. A.

10.1101/2024.03.04.583351 — ecology — Posted on 2024-03-07

4044 Technical and biological variations in the purification of extrachromosomal circular DNA (eccDNA) and the finding of more eccDNA in the plasma of lung adenocarcinoma patients compared with healthy donors

Zole, E.; Hansen, L. B.; Hasko, J.; Gerovska, D.; Arauzo-Bravo, M. J.; Noer, J. B.; Luo, Y.; Johansen, J. S.; Regenberg, B.

10.1101/2024.03.05.583481 — molecular biology — Posted on 2024-03-07

4045 Nucleotidyltransferase toxin MenT targets and extends the aminoacyl acceptor ends of serine tRNAs in vivo to control Mycobacterium tuberculosis growth

XU, X.; BARRIOT, R.; VOISIN, B.; ARROWSMITH, T. J.; USHER, B.; GUTIERREZ, C.; HAN, X.; REDDER, P.; BLOWER, T. R.; NEYROLLES, O.; GENEVAUX, P.

10.1101/2024.03.07.583660 — microbiology — Posted on 2024-03-07

4046 Seasonal Patterns of Viromes in Urban Aquatic Environments of Manitoba

Francis, J. D.; Uyaguari Diaz, M.

10.1101/2024.03.06.583751 — microbiology — Posted on 2024-03-07

4047 A history of repeated antibiotic usage leads to microbiota-dependent mucus defects

Krigul, K. L.; Feeney, R. H.; Wongkuna, S.; Aasmets, O.; Holmberg, S. M.; Andreson, R.; Puertolas-Balint, F.; Pantiukh, K.; Sootak, L.; Org, T.; Tenson, T.; Org, E.; Schroeder, B. O.

10.1101/2024.03.07.583875 — microbiology — Posted on 2024-03-07

4048 Inducible deletion of Ezh2 in CD4+ T cells inhibits kidney T cell infiltration and prevents interstitial nephritis in MRL/lpr lupus-prone mice

Zheng, X.; Dozmorov, M. G.; Espinoza, L.; Bowes, M. M.; Bastacky, S.; Sawalha, A. H.

10.1101/2024.03.04.583401 — immunology — Posted on 2024-03-07

4049 A Novel Humanized Mouse Model for HIV and Tuberculosis Co-infection Studies

Yi, G.; Bohorquez, J. A.; Adduri, S.; Ansari, D.; John, S.; Florence, J.; Adejare, O.; Singh, G.; Konduru, N. V.; Jagannath, C.

10.1101/2024.03.05.583545 — immunology — Posted on 2024-03-07

4050 An ethologically relevant paradigm to assess visual contrast sensitivity in rodents

Calanni, J. S.; Aranda, M. L.; Dieguez, H. H.; Dorfman, D.; Schmidt, T. M.; Rosenstein, R. E.

10.1101/2024.03.05.583559 — neuroscience — Posted on 2024-03-07

4051 Extended Poisson Gaussian-Process Latent Variable Model for Unsupervised Neural Decoding

Luo, D. D.; Giri, B.; Diba, K.; Kemere, C.

10.1101/2024.03.04.583340 — neuroscience — Posted on 2024-03-07

4052 Inefficient Endocytosis Limits Heterotrimeric G Protein Abundance on Endosomes

Jang, W.; Senarath, K.; Lu, S.; Lambert, N. A.

10.1101/2024.03.05.583500 — pharmacology and toxicology — Posted on 2024-03-07

4053 DR5 disulfide bonding as a sensor and effector of protein folding stress

Law, M. E.; Dulloo, Z. M.; Eggleston, S. R.; Takacs, G. P.; Alexandrow, G. M.; Wang, M.; Su, H.; Forsyth, B. A.; Chiang, C.-W.; Sharma, A.; Kanumuri, S. R. R.; Guryanova, O. A.; Harrison, J. K.; Tirosh, B.; Castellano, R. K.; Law, B. K.

10.1101/2024.03.04.583390 — cancer biology — Posted on 2024-03-07

4054 Evolutionary trajectories of IDH-mutant astrocytoma identify molecular grading markers related to cell cycling

Vallentgoed, W. R.; Hoogstrate, Y.; van Garderen, K. A.; van Hijfte, L.; van Dijk, E.; Kouwenhoven, M. C.; Niers, J. M.; Draaisma, K.; Martin, I.; de Leng, W. W.; Tesileanu, C. M. S.; de Heer, I.; Diepeveen, M.; Lavrova, A.; Eijk, P. P.; Buehler, M.; Wick, W.; Clement, P. M.; Sanson, M.; Franceschi, E.; Gorlia, T.; Golfinopoulos, V.; Weller, M.; Weiss, T.; Robe, P. A.; Kros, J. M.; Smits, M.; van de Wiel, M.; Ylstra, B.; Verhaak, R. G.; van den Bent, M. J.; Westerman, B.; Wesseling, P.; French, P. J.

10.1101/2024.03.05.583306 — cancer biology — Posted on 2024-03-07

4055 Iterative in silico identification of P-glycoprotein inhibitors

McCormick, L. A.; McCormick, J. W.; Park, C.; Wise, J. G.; Vogel, P. D.

10.1101/2024.03.05.583428 — cancer biology — Posted on 2024-03-07

4056 Probing recombinant AAV capsid integrity and genome release under thermal stress by single-molecule interferometric scattering microscopy

Ebberink, E. H. T. M.; Ruisinger, A.; Nuebel, M.; Meyer-Berg, H.; Ferreira, I. R. S.; Thomann, M.; Heck, A. J. R.

10.1101/2024.03.07.583968 — biophysics — Posted on 2024-03-07

4057 Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response

Huang, H.-C.; Lobo, V.; Schon, K.; Nowak, I.; Westholm, J. O.; Fernandez, C.; Patel, A. A.; Wiel, C.; Sayin, V. I.; Anastasakis, D. G.; Angeletti, D.; Sarshad, A.

10.1101/2024.03.07.583365 — biochemistry — Posted on 2024-03-07

4058 Time-separated Mutual Information Reveals Key Characteristics of Asymmetric Leader-Follower Interactions in Golden Shiners

Daftari, K.; Mayo, M. L.; Lemasson, B. H.; Biedenbach, J. M.; Pilkiewicz, K. R.

10.1101/2024.03.05.583541 — animal behavior and cognition — Posted on 2024-03-07

4059 Persistent Behavioral and Physiological Effects of Dietary Protein Restriction

Soto, P.; Morrison, C.

10.1101/2024.03.04.583396 — animal behavior and cognition — Posted on 2024-03-07

4060 Intrinsically linked lineage-specificity of transposable elements and lncRNAs reshapes transcriptional regulation species- and tissue-specifically

Lin, J.; Wu, Y.; Xiong, W.; He, S.; Pontarotti, P.; ZHU, H.

10.1101/2024.03.04.583292 — genomics — Posted on 2024-03-07

4061 A male-essential microRNA is key for avian sex chromosome dosage compensation

Fallahshahroudi, A.; Rodriguez-Montes, L.; Yousefi Taemeh, S.; Trost, N.; Tellez, M.; Ballantyne, M.; Idoko-Akoh, A.; Taylor, L.; Sherman, A.; Sorato, E.; Johnsson, M.; Cardoso Moreira, M.; McGrew, M.; Kaessmann, H.

10.1101/2024.03.06.581755 — evolutionary biology — Posted on 2024-03-07

4062 Intraspecific variation of thermal tolerance in freshwater insects along elevational gradients: the case of a widespread diving beetle

Pallares, S.; Carbonell, J. A.; Picazo, F.; Bilton, D. T.; Millan, A.; Abellan, P.

10.1101/2024.03.04.583263 — ecology — Posted on 2024-03-07

4063 EyeHex toolbox for complete segmentation of ommatidia in fruit fly eyes

Tran, H.; DOSTATNI, N.; Ramaekers, A.

10.1101/2024.03.04.583398 — developmental biology — Posted on 2024-03-07

4064 Subnanometer structure of medusavirus capsid during maturation using cryo-electron microscopy

Watanabe, R.; Song, C.; Takemura, M.; Murata, K.

10.1101/2024.03.07.583866 — molecular biology — Posted on 2024-03-07

4065 Uncovering the transcriptional molecular dynamics of shelf life extension and system acquired resistance induction to Fusarium pallidoroseum in melon fruits by the use of pulsed-light

Arge, L. W. P.; Morais, G. L.; Carvalho, J. B.; Zocolo, G. J.; Oster, A. H.; Vasconcelos, A. T. R. d.; Diniz, L. E. C.; Silva, E. d. O.; Bordallo, P. d. N.

10.1101/2024.03.05.583617 — molecular biology — Posted on 2024-03-07

4066 CemR atypical response regulator impacts energy conversion in Campylobacteria

Noszka, M.; Strzalka, A.; Muraszko, J.; Hofreuter, D.; Abele, M.; Ludwig, C.; Stingl, K.; Pawlik, A. M.

10.1101/2024.03.07.583886 — molecular biology — Posted on 2024-03-07

4067 Eukaryotic initiation factor 3F (eIF3F) regulates the IRES-mediated translation of Bcl-xL via its interaction with programmed cell death 4 (PDCD4) protein

Hegde, V.; Sharma, D. K.; Patel, H.; Narasimha, P.; Luddu, J.; Holcik, M.; Thakor, N.

10.1101/2024.03.04.583409 — molecular biology — Posted on 2024-03-07

4068 PhyloForge: Unifying micro and macro evolution with comprehensive genomic signals

Wang, Y.; Dong, W.; Liang, Y.; Chen, F.

10.1101/2024.03.06.583656 — molecular biology — Posted on 2024-03-07

4069 Coronavirus Nucleocapsid Protein Enhances the binding of p-PKCα to RACK1: Implications for Inhibition of Nucleocytoplasmic Trafficking and Suppression of the Innate Immune Response

Liao, Y.; Xue, W.; Chu, H.; Wang, J.; Sun, Y.; Qiu, X.; Song, C.; Tan, L.; Ding, C.

10.1101/2024.03.06.583677 — microbiology — Posted on 2024-03-07

4070 Deciphering lentiviral Vpr/x determinants required for HUSH and SAMHD1 antagonism highlights the molecular plasticity of these evolutionary conflicts

Larrous, P.; Garnier, C.; Martin, M. M.; Morel, M.; Zarrouk, K.; Maesen, S.; Matkovic, R.; Cimarelli, A.; Etienne, L.; Margottin-Goguet, F.

10.1101/2024.03.07.583867 — microbiology — Posted on 2024-03-07

4071 HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14

Blakely, W. J.; Hatterschide, J.; White, E. A.

10.1101/2024.03.07.583953 — microbiology — Posted on 2024-03-07

4072 Experimental challenge of Chinook salmon with Tenacibaculum maritimum and Tenacibaculum dicentrarchi fulfils Kochs postulates

Kumanan, K.; Carson, J.; Hunter, R. B. J.; Rolton, A.; von Ammon, U.; Bandaranayake, C.; Angelucci, C.; Morrison, R. N.; Walker, S. P.; Symonds, J. E.; Hutson, K. S.

10.1101/2024.03.06.583827 — microbiology — Posted on 2024-03-07

4073 Bacteriophage resistance increases bacterial productivity by shifting population growth dynamics in the soil bacterium Variovorax sp.

Castledine, M.; Padfield, D.; Lewis, R.; Buckling, A.

10.1101/2024.03.07.583923 — microbiology — Posted on 2024-03-07

4074 Development of antibacterial drug plus bacteriophage combination assays

Attwood, M. E.; Griffin, P.; NOEL, A. R.; Josephs, T.; Adler, K.; Cloke, M. R.; MacGowan, A. P.

10.1101/2024.03.07.583836 — microbiology — Posted on 2024-03-07

4075 Protocatechuic acid induces endogenous oxidative stress in CR-hvKP by regulating the EMP-PPP pathway

Zhong, Y.; Cheng, Y.; Xing, S.; Zhang, X.; Luo, S.; Shi, X.; He, Y.; Liu, H.; Yang, M.; Si, H.-B.

10.1101/2024.03.06.583678 — microbiology — Posted on 2024-03-07

4076 The segmented flavivirus Alongshan virus reduces mitochondrial mass via degrading STAT2 to suppress innate immune response

Zhao, Y.; Sui, L.; Pan, M.; Jin, F.; Huang, Y.; Fang, S.; Wang, M.; Che, L.; Xu, W.; Liu, N.; Liu, N.; Gao, H.; Hou, Z.; Du, F.; Wei, Z.; Zhao, J.; Zhang, K.; Zhao, Y.; Wang, Z.-D.; Liu, Q.

10.1101/2024.03.06.583679 — microbiology — Posted on 2024-03-07

4077 Long distance avian migrants fail to bring 2.3.4.4b HPAI H5N1 into Australia for a second year in a row

Wille, M.; Atkinson, R.; Barr, I. G.; Burgoyne, C.; Bond, A. L.; Boyle, D.; Christie, M.; Dewar, M.; Douglas, T.; Fitzwater, T.; Hassell, C.; Jessop, R.; Klaassen, H.; Lavers, J. L.; Leung, K. K.- S.; Ringma, J.; Sutherland, D. R.; Klaassen, M.

10.1101/2024.03.06.583767 — microbiology — Posted on 2024-03-07

4078 Dynamic Adaptation in Extant Porins Facilitates Antibiotic Tolerance in Energetic Escherichia coli

Mukhopadhyay, S.; Bishayi, R.; Shaji, A.; Lee, A. H.; Gupta, R.; Mohajeri, M.; Katiyar, A.; McKee, B.; Schmitz, I. R.; Shin, R.; Lele, T. P.; Lele, P. P.

10.1101/2024.03.07.583920 — microbiology — Posted on 2024-03-07

4079 Mapping the mutational landscape of a full viral proteome reveals distinct profiles of mutation tolerability

Alvarez-Rodriguez, B.; Velandia-Alvarez, S.; Toft, C.; Geller, R.

10.1101/2024.03.07.583990 — microbiology — Posted on 2024-03-07

4080 Role of Hepatocyte RIPK1 in Maintaining Liver Homeostasis during Metabolic Challenges

Zhang, W.; Zhang, D.; Yi, Y.; Tao, L.; Zhao, X.; Shao, Q.; Li, P.; Zhang, J.; Zhang, H.; Chen, Y.; Weng, D.

10.1101/2024.03.04.583302 — immunology — Posted on 2024-03-07

4081 DeepPrep: An accelerated, scalable, and robust pipeline for neuroimaging preprocessing empowered by deep learning

Ren, J.; An, N.; Lin, C.; Zhang, Y.; Sun, Z.; Zhang, W.; Li, S.; Guo, N.; Cui, W.; Hu, Q.; Wang, W.; Wu, X.; Wang, Y.; Jiang, T.; Satterthwaite, T. D.; Wang, D.; Liu, H.

10.1101/2024.03.06.581108 — neuroscience — Posted on 2024-03-07

4082 Comprehensive mapping of sensory and sympathetic innervation of the developing kidney

N'Guetta, P.-E. Y.; McLarnon, S. R.; Tassou, A.; Geron, M.; Shirvan, S.; Hill, R. Z.; Scherrer, G.; O'Brien, L. L.

10.1101/2023.11.15.567276 — developmental biology — Posted on 2024-03-07

4083 Defining the EM-signature of successful cell-transfection

Pemberton, J. G.; Tenkova, T.; Felgner, P. L.; Zimmerberg, J.; Balla, T.; Heuser, J. E.

10.1101/2024.03.07.583927 — cell biology — Posted on 2024-03-07

4084 Identification of ESCRT-III like protein sequences in yeast

Brune, T.; Kölling, R.

10.1101/2024.03.07.583924 — cell biology — Posted on 2024-03-07

4085 Single-cell analysis identifies distinct macrophage phenotypes associated with pro-disease and pro-resolving functions in the endometriotic niche

Henlon, Y.; Panir, K.; McIntyre, I.; Hogg, C.; Dhami, P.; Cuff, A. O.; Senior, A.; Moolchandani-Adwani, N.; Courtois, E. T.; Horne, A. W.; Rosser, M.; Ott, S.; Greaves, E.

10.1101/2024.03.07.583861 — immunology — Posted on 2024-03-07

4086 Cell autonomous role of leucine-rich repeat kinase in protection of dopaminergic neuron survival

Kang, J.; Huang, G.; Ma, L.; Tong, Y.; Shahapal, A.; Chen, P.; Shen, J.

10.1101/2023.10.06.561293 — neuroscience — Posted on 2024-03-07

4087 Low-frequency hearing thresholds improve as high-frequency hearing sensitivity deteriorates between young adulthood and middle age in normally hearing people

Izmaylova, T.; Undurraga, J.; Sowman, P. F.

10.1101/2024.03.06.583598 — physiology — Posted on 2024-03-07

4088 The combination of differential expression and differential network connectivity analyses identifies RNA splicing and processing as common pathways altered with age across human tissues

Batalha, C. M. P. F.; Fujita, A.; de Souza-Pinto, N. C.

10.1101/2023.05.26.542445 — bioinformatics — Posted on 2024-03-07

4089 GUANinE v1.0: Benchmark Datasets for Genomic AISequence-to-Function Models

Robson, E. S.; Ioannidis, N. M.

10.1101/2023.10.12.562113 — genomics — Posted on 2024-03-07

4090 Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent

Korfmann, K.; Sellinger, T. P. P.; Freund, F.; Fumagalli, M.; Tellier, A.

10.1101/2022.09.28.508873 — genetics — Posted on 2024-03-07

4091 Thymic epithelial organoids mediate T cell development

Hubscher, T.; Lorenzo-Martin, F.; Barthlott, T.; Tillard, L.; Langer, J.; Rouse, P.; Blackburn, C.; Hollander, G. C.; Lutolf, M.

10.1101/2024.03.05.583513 — developmental biology — Posted on 2024-03-07

4092 Spatiotemporal regulation of Pseudorabies Virus Thymidine kinase UL23 by post-translational modification

Li, C.; Cao, R.; Zhang, R.; Tang, J.

10.1101/2024.03.06.583799 — cell biology — Posted on 2024-03-07

4093 Nano-scale viscometry reveals an inherent mucus defect in cystic fibrosis

Ponomarchuk, O.; Boudreault, F.; Gryczynski, I.; Dzyuba, S. V.; Fudala, R.; Gryczynski, Z.; Hanrahan, J. W.; Grygorczyk, R.

10.1101/2024.03.06.583796 — cell biology — Posted on 2024-03-07

4094 Nature AND Nurture: Enabling formate-dependent growth in Methanosarcina acetivorans

Bao, J.; Somvanshi, T.; Tian, Y.; Laird, M.; Garcia, P. S.; Schoene, C.; Rother, M.; Borrel, G.; Scheller, S.

10.1101/2024.01.08.574737 — microbiology — Posted on 2024-03-07

4095 Integrating mechanism-based T cell phenotypes into a model of tumor-immune cell interactions

Tangella, N.; Cess, C. G.; Ildefonso, G. V.; Finley, S. D.

10.1101/2024.03.05.583613 — systems biology — Posted on 2024-03-07

4096 Agent-based model demonstrates the impact of nonlinear, complex interactions between cytokines on muscle regeneration

Haase, M.; Comlekoglu, T.; Petrucciani, A.; Peirce, S. M.; Blemker, S. S.

10.1101/2023.08.14.553247 — systems biology — Posted on 2024-03-07

4097 Sympathetic Motor Neuron Dysfunction is a Missing Link in Age-Associated Sympathetic Overactivity

de la Cruz, L.; Bui, D.; Moreno, C. M.; Vivas, O.

10.1101/2023.09.27.559800 — physiology — Posted on 2024-03-07

4098 Large- and Small-Animal Studies of Safety, Pharmacokinetics (PK), and Biodistribution of Inflammasome-Targeting Nanoligomer in the Brain and Other Target Organs

Risen, S.; Kusick, B.; Sharma, S.; Gilberto, V.; Brindley, S.; Aguilar, M.; Brown, J.; McGrath, S.; Chatterjee, A.; Moreno, J.; Nagpal, P.

10.1101/2024.02.07.579323 — pharmacology and toxicology — Posted on 2024-03-07

4099 Advancing Drug-Target Interactions Prediction: Leveraging a Large-Scale Dataset with a Rapid and Robust Chemogenomic Algorithm.

Guichaoua, G.; Pinel, P.; Hoffmann, B.; Azencott, C.-A.; Stoven, V.

10.1101/2024.02.22.581599 — bioinformatics — Posted on 2024-03-07

4100 Computational design of soluble functional analogues of integral membrane proteins

Goverde, C. A.; Pacesa, M.; Goldbach, N.; Balbi, P. E.; Dornfeld, L. J.; Georgeon, S.; Rosset, S.; Kapoor, S.; Choudhury, J.; Dauparas, J.; Shellhaas, C.; Kozlov, S.; Baker, D.; Ovchinnikov, S.; Vecchio, A. J.; Correia, B.

10.1101/2023.05.09.540044 — bioinformatics — Posted on 2024-03-07

4101 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

Nazeen, S.; Wang, X.; Zielinski, D.; Lam, I.; Hallacli, E.; Xu, P.; Ethier, E.; Strom, R.; Zanella, C. A.; Nithianandam, V.; Ritter, D.; Henderson, A.; Saurat, N.; Afroz, J.; Nutter-Upham, A.; Benyamini, H.; Copty, J.; Ravishankar, S.; Morrow, A.; Mitchel, J.; Neavin, D.; Gupta, R.; Farbehi, N.; Grundman, J.; Myers, R. H.; Scherzer, C. R.; Trojanowski, J. Q.; Van Deerlin, V. M.; Cooper, A. A.; Lee, E. B.; Erlich, Y.; Lindquist, S.; Peng, J.; Geschwind, D. H.; Powell, J.; Studer, L.; Feany, M. B.; Sunyaev, S. R.; Khurana, V.

10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-07

4102 In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma

Liu, S. J.; Pak, J.; Zou, C.; Casey-Clyde, T.; Borah, A.; Wu, D.; Seo, K.; O'Loughlin, T.; Lim, D.; Ozawa, T.; Berger, M.; Weiss, W.; Raleigh, D. R.; Gilbert, L. A.

10.1101/2023.09.01.555831 — genomics — Posted on 2024-03-07

4103 The nerodevelopmental genes alan shepard and Neuroglian contribute to female mate preference in African Drosophila melanogaster

Roy, P. R.; Castillo, D. M.

10.1101/2022.05.15.491994 — evolutionary biology — Posted on 2024-03-07

4104 CLEM-Reg: An automated point cloud based registration algorithm for correlative light and volume electron microscopy

Krentzel, D.; Elphick, M.; Domart, M.-C.; Peddie, C. J.; Laine, R. F.; Henriques, R.; Collinson, L. M.; Jones, M. L.

10.1101/2023.05.11.540445 — cell biology — Posted on 2024-03-07

4105 Link between lipid remodeling and ESCRT-III function in multivesicular body formation

Koelling, R.

10.1101/2023.10.10.561655 — cell biology — Posted on 2024-03-07

4106 DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genes

Lorzadeh, A.; Ye, G.; Sharma, S.; Jadhav, U.

10.1101/2024.02.11.579850 — molecular biology — Posted on 2024-03-07

4107 Unraveling and quantifying "Candidatus Saccharibacteria": in silico and experimental evaluation of V3-V4 16S rRNA metagenomics and qPCR protocols

Papaleo, S.; Nodari, R.; Sterzi, L.; D'Auria, E.; Cattaneo, C.; Bettoni, G.; Bonaiti, C.; Pagliarini, E.; Zuccotti, G. V.; Panelli, S.; Comandatore, F.

10.1101/2024.03.06.583507 — microbiology — Posted on 2024-03-07

4108 Protein design for evaluating vaccines against future viral variation

Youssef, N.; Gurev, S.; Ghantous, F.; Brock, K. P.; Jaimes, J. A.; Thadani, N. N.; Dauphin, A.; Sherman, A. C.; Yurkovetskiy, L.; Soto, D.; Estanboulieh, R.; Kotzen, B.; Notin, P.; Kollasch, A. W.; Cohen, A. A.; Dross, S. E.; Erasmus, J.; Fuller, D. H.; Bjorkman, P. J.; Lemieux, J. E.; Luban, J.; Seaman, M. S.; Marks, D.

10.1101/2023.10.08.561389 — immunology — Posted on 2024-03-07

4109 Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in SCN8A Epileptic Encephalopathy

Miralles, R. M.; Boscia, A. R.; Kittur, S.; Vundela, S. R.; Wengert, E. R.; Patel, M. K.

10.1101/2024.02.09.579511 — neuroscience — Posted on 2024-03-07

4110 Anticipatory and evoked visual cortical dynamics of voluntary temporal attention

Denison, R. N.; Tian, K.; Heeger, D. J.; Carrasco, M.

10.1101/2022.11.18.517084 — neuroscience — Posted on 2024-03-07

4111 Practical Bayesian Inference in Neuroscience: Or How I Learned To Stop Worrying and Embrace the Distribution

Coventry, B. S.; Bartlett, E. L.

10.1101/2023.11.19.567743 — neuroscience — Posted on 2024-03-07

4112 Endogenous Intracellular Metabolites Allosterically Modulate GPCR-Gα Interface

Mohanty, S. K.; Mittal, A.; Gaur, A.; Namra, ; Duari, S.; Solanki, S.; Sharma, A. K.; Arora, S.; Kumar, S.; Gautam, V.; Dixit, N. K.; Subramanian, K.; Ghosh, T. S.; Sengupta, D.; Sharma, D.; Gupta, S. K.; Murugan, N. A.; Ahuja, G.

10.1101/2023.02.14.528587 — bioinformatics — Posted on 2024-03-07

4113 A short 3'UTR motif regulates gene expression in bilaterians

Eufrasio, A.; Azevedo, J.; Machado, J.; Ferreira, A.; Moutinho, A.; Henriques, F.; Jesus, A.; Tavares, J.; Pereira-Castro, I.; Teixeira, J.; Araujo, M.; Pinto, P. A.; Bessa, J.; Moreira, A.

10.1101/2023.11.15.567165 — molecular biology — Posted on 2024-03-07

4114 Entrainment Echoes in the Cerebellum

Zoefel, B.; Abbasi, O.; Gross, J.; Kotz, S. A.

10.1101/2024.03.06.583255 — neuroscience — Posted on 2024-03-07

4115 A new archaeal virus that suppresses the transcription of host immunity genes

Turgeman-Grott, I.; Golan, N.; Neri, U.; Naki, D.; Altman-Price, N.; Eizenshtein, K.; Choudhary, D. K.; Levy, R.; Himani, H.; Shalev, Y.; Reshef, L.; Gophna, U.

10.1101/2024.02.12.579488 — microbiology — Posted on 2024-03-07

4116 Not fleeting but lasting: Limited influence of aging on implicit adaptative motor learning and its short-term retention.

Hermans, P.; Vandevoorde, K.; Orban de Xivry, J.-J.

10.1101/2023.08.30.555501 — neuroscience — Posted on 2024-03-07

4117 Sensorimotor mechanisms selective to numerosity: evidence from individual differences

Anobile, G.; Petrizzo, I.; Paiardini, D.; Burr, D.; Cicchini, G. M.

10.1101/2023.10.04.560837 — neuroscience — Posted on 2024-03-07

4118 Thermal Contrast Enhancement Predicts Paradoxical Heat Sensation

Mitchell, A. G.; Fischer Ehmsen, J.; Basinska, M.; Courtin, A. S.; Bohme, R. A.; Sardeto Deolindo, C.; Allen, M. G.; Sandberg, K.; Fardo, F.

10.1101/2023.08.23.554435 — neuroscience — Posted on 2024-03-07

4119 External task switches activate default mode regions without enhanced processing of the surrounding scene

Zhou, A. X.; Duncan, J.; Mitchell, D. J.

10.1101/2024.03.04.583347 — neuroscience — Posted on 2024-03-07

4120 The developing mouse dopaminergic system: Cortical-subcortical shift in D1/D2 receptor balance and increasing regional differentiation

Bjerke, I. E.; Carey, H.; Bjaalie, J. G.; Leergaard, T. B.; Kim, J. H.

10.1101/2024.03.05.583309 — neuroscience — Posted on 2024-03-07

4121 Cell-type specific contributions to theta-gamma coupled rhythms in the hippocampus

Sengupta, S.; Talidou, A.; Lefebvre, J.; Skinner, F.

10.1101/2024.03.05.583493 — neuroscience — Posted on 2024-03-07

4122 The role of olivary phase-locking oscillations in cerebellar sensorimotor adaptation

Luque, N. R.; Carrillo, R. R.; Naveros, F.; Ros, E.; Arleo, A.

10.1101/2024.03.06.583676 — neuroscience — Posted on 2024-03-07

4123 Neurodevelopmental defects in Dravet syndrome Scn1a+/- mice: selective rescue of behavioral alterations but not seizures by targeting GABA-switch.

Pizzamiglio, L.; Capitano, F.; Rusina, E.; Fossati, G.; Menna, E.; Lena, I.; Antonucci, F.; Mantegazza, M.

10.1101/2024.03.06.583652 — neuroscience — Posted on 2024-03-07

4124 Glutamate signaling and neuroligin/neurexin adhesion play opposing roles that are mediated by major histocompatibility complex I molecules in cortical synapse formation

Sell, G. L.; Barrow, S. L.; McAllister, A. K.

10.1101/2024.03.05.583626 — neuroscience — Posted on 2024-03-07

4125 Persistent Interruption in Parvalbumin Positive Inhibitory Interneurons: Biophysical and Mathematical Mechanisms

Canavier, C. C.; Upchurch, C. M.; Knowlton, C.; Chamberland, S.

10.1101/2024.03.04.583352 — neuroscience — Posted on 2024-03-07

4126 Task structure tailors the geometry of neural representations in human lateral prefrontal cortex

Bhandari, A.; Keglovits, H.; Chicklis, E.; Badre, D.

10.1101/2024.03.06.583429 — neuroscience — Posted on 2024-03-07

4127 Subtypes of brain change in aging and their associations with cognition and Alzheimer's disease biomarkers

Capogna, E.; Sorensen, O.; Watne, L. O.; Roe, J.; Stromstad, M.; Idland, A. V.; Halaas, N. B.; Blennow, K.; Zetterberg, H.; Walhovd, K. B.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle Flagship Study of Ageing, ; Fjell, A. M.; Vidal-Pineiro, D.

10.1101/2024.03.04.583291 — neuroscience — Posted on 2024-03-07

4128 Comparing the limbic-frontal connectome across the primate order: conservation of connections and implications for translational neuroscience

Folloni, D.; Roumazeilles, L.; Bryant, K. L.; Manger, P. R.; Bertelsen, M. F.; Khrapitchev, A. A.; Rudebeck, P. H.; Mars, R. B.

10.1101/2024.03.06.583735 — neuroscience — Posted on 2024-03-07

4129 Endocannabinoid biomarkers of vulnerability to the development of trauma-induced generalized fear responses

Szente, L.; Balla, G. Y.; Varga, Z. K.; Toth, B.; Biro, L.; Balogh, Z.; Hill, M. N.; Toth, M.; Mikics, E.; Aliczki, M.

10.1101/2024.03.06.583339 — neuroscience — Posted on 2024-03-07

4130 Temporal attention recruits fronto-cingulate cortex to amplify stimulus representations

Zhu, J.; Tian, K.; Carrasco, M.; Denison, R. N.

10.1101/2024.03.06.583738 — neuroscience — Posted on 2024-03-07

4131 Developmental trajectory of cortical somatostatin interneuron function

Wang, A.; Ferguson, K. A.; Gupta, J.; Higley, M. J.; Cardin, J. A.

10.1101/2024.03.05.583539 — neuroscience — Posted on 2024-03-07

4132 Human Anterior Insular Cortex Encodes Multiple Electrophysiological Representations of Anxiety-Related Behaviors

Lee, A. M.; Sturm, V.; Dawes, H.; Krystal, A. D.; Chang, E.

10.1101/2024.03.05.583610 — neuroscience — Posted on 2024-03-07

4133 Electrophysiological correlates of divergent projections in the avian superior olivary nucleus

Baldassano, J.; MacLeod, K. M.

10.1101/2024.03.06.583566 — neuroscience — Posted on 2024-03-07

4134 Predictive learning shapes the representational geometry of the human brain

Greco, A.; Moser, J.; Preissl, H.; Siegel, M.

10.1101/2024.03.07.583842 — neuroscience — Posted on 2024-03-07

4135 MYT1L deficiency impairs excitatory neuron trajectory during cortical development

Yen, A.; Chen, X.; Skinner, D. D.; Leti, F.; Crosby, M.; Hoisington-Lopez, J.; Wu, Y.; Chen, J.; Mitra, R. D.; Dougherty, J. D.

10.1101/2024.03.06.583632 — neuroscience — Posted on 2024-03-07

4136 Up-regulation of cholesterol synthesis by lysosomal defects requires a functional mitochondrial respiratory chain

Agostini, F.; Pereyra, L.; Dale, J.; Yambire, K. F.; Maglioni, S.; Schiavi, A.; Ventura, N.; Milosevic, I.; Raimundo, N.

10.1101/2024.03.06.583589 — biochemistry — Posted on 2024-03-07

4137 The mutational landscape of Bacillus subtilis conditional hypermutators shows how proofreading skews DNA polymerase error rates

Tanneur, I.; Dervyn, E.; Guerin, C.; Kon Kam King, G.; Jules, M.; Nicolas, P.

10.1101/2023.12.29.573609 — genomics — Posted on 2024-03-07

4138 Light-speed whole genome association testing and prediction via Approximate Message Passing

Depope, A.; Mondelli, M.; Robinson, M. R.

10.1101/2023.09.14.557703 — genetics — Posted on 2024-03-07

4139 Domain general frontoparietal regions show modality-dependent coding of auditory and visual rules

Jackson, J. B.; Rich, A. N. B.; Moerel, D.; Teichmann, L.; Duncan, J.; Woolgar, A.

10.1101/2024.03.04.583318 — neuroscience — Posted on 2024-03-07

4140 Transcriptomic Dissection of the AMF-Solanum melongena Interaction: Unveiling Molecular Secrets

Jha, S. S.; Songachan, L. S.

10.1101/2024.02.17.580814 — plant biology — Posted on 2024-03-07

4141 Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping

Li, Z.; Katz, S.; Saccenti, E.; Fardo, D.; Claes, P.; Martins dos Santos, V. A. P.; Van Steen, K.; Roshchupkin, G. V.

10.1101/2024.02.05.578873 — genomics — Posted on 2024-03-07

4142 Knotted artifacts in predicted 3D RNA structures

Gren, B. A.; Antczak, M.; Zok, T.; Sulkowska, J. I.; Szachniuk, M.

10.1101/2024.03.04.583268 — bioinformatics — Posted on 2024-03-07

4143 ENT3C: an entropy-based similarity measure for Hi-C and micro-C derived contact matrices

Lainscsek, X.; Taher, L.

10.1101/2024.01.30.577923 — bioinformatics — Posted on 2024-03-07

4144 In Vitro Budding and Floatation based enrichment of Mitochondria-derived Vesicles for Proteomics from Rat Heart

Nair, N. Y.; Ramesh, L.; Marib, A.; Rajeeve, T.; Johnson, J. B.; Sundararaman, A.

10.1101/2024.03.04.583262 — cell biology — Posted on 2024-03-07

4145 Specific Sensitivity to Rare and Extreme Events: Quasi-Complete Black Swan Avoidance vs Partial Jackpot Seeking in Rat Decision-Making

Degoulet, M.; Willem, L.-M.; Baunez, C.; Luchini, S.; Pintus, P.

10.1101/2021.11.01.466806 — animal behavior and cognition — Posted on 2024-03-07

4146 Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity

Carmi, Y.; Farhat-Younis, L.; Na, M.; Zarfin, A.; Santana-Magal, N.; Richter, A.; Khateeb, A.; Gutwillig, A.; Rasoulouniriana, D.; Gleiberman, A.; Beck, L.; Giger, T.; Ashkenazi, A.; Barzel, A.; Rider, P.

10.1101/2023.09.30.560338 — immunology — Posted on 2024-03-07

4147 Quantifying Harmony between Direct and Indirect Pathways in The Basal Ganglia; Healthy and Parkinsonian States

Kim, S.-Y.; Lim, W.

10.1101/2023.09.19.558549 — neuroscience — Posted on 2024-03-07

4148 Noradrenergic locus coeruleus activity functionally partitions NREM sleep to gatekeep the NREM-REM sleep cycle

Osorio-Forero, A.; Foustoukos, G.; Cardis, R.; Cherrad, N.; Devenoges, C.; Fernandez, L. M.; Luthi, A.

10.1101/2023.05.20.541586 — neuroscience — Posted on 2024-03-07

4149 Unsupervised generative AI discovers pan-leukocyte dysregulated pathways in single-cell lupus data

Bolouri, H.; Cerosaletti, K.; Lacy-Hulbert, A.

10.1101/2024.03.02.583143 — bioinformatics — Posted on 2024-03-07

4150 In vivo perturb-seq of cancer and microenvironment cells dissects oncologic drivers and radiotherapy responses in glioblastoma

Liu, S. J.; Pak, J.; Zou, C.; Casey-Clyde, T.; Borah, A.; Wu, D.; Seo, K.; O'Loughlin, T.; Lim, D.; Ozawa, T.; Berger, M.; Weiss, W.; Raleigh, D. R.; Gilbert, L. A.

10.1101/2023.09.01.555831 — genomics — Posted on 2024-03-07

4151 MASH: Mediation Analysis of Survival Outcome and High-dimensional Omics Mediators with Application to Complex Diseases

Chi, S.; Flowers, C. R.; Li, Z.; Huang, X.; Wei, P.

10.1101/2023.08.22.554286 — genomics — Posted on 2024-03-07

4152 Dual-color MINFLUX: Kinesin-1 takes Chasse-Inchworm steps

Scheiderer, L.; Wirth, J. O.; Tarnawski, M.; Hell, S. W.

10.1101/2024.03.05.583551 — biophysics — Posted on 2024-03-06

4153 An Allosteric Cholesterol Site in Glycine Receptors Characterized Through Molecular Simulations

Jalalypour, F.; Howard, R. J.; Lindahl, E.

10.1101/2024.03.05.583408 — biophysics — Posted on 2024-03-06

4154 The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics

10.1101/2023.09.25.559365 — genomics — Posted on 2024-03-06

4155 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-06

4156 Human Pluripotent Stem Cell Derived Organoids Reveal a Role for WNT Signaling in Dorsal-Ventral Patterning of the Hindgut

Qu, N.; Daoud, A.; Kechele, D. O.; Munera, J. O.

10.1101/2024.03.04.583343 — developmental biology — Posted on 2024-03-06

4157 Roles of TYRO3 Family Receptors in Germ Cell Development During Mouse Testis Formation

Ming, Z.; Bagheri-Fam, S.; Frost, E. R.; Ryan, J. M.; Binder, M. D.; Harley, V. R.

10.1101/2024.03.05.583252 — developmental biology — Posted on 2024-03-06

4158 Astrocytes in the mouse suprachiasmatic nuclei respond directly to glucocorticoids feedback

Haendler, K.; Sreenivasan, V. K. A.; Pilorz, V.; Bringas, J. O.; Castanondo, L. E.; Bengoa-Vergniory, N.; Oster, H.; Spielmann, M.; Astiz, M.

10.1101/2024.03.04.583323 — developmental biology — Posted on 2024-03-06

4159 Circular RNA HMGCS1 sponges miR-4521 to aggravate type 2 diabetes-induced vascular endothelial dysfunction

Zhang, M.; Du, G.; Xie, L.; Xu, Y.; Chen, W.

10.1101/2024.03.06.583717 — cell biology — Posted on 2024-03-06

4160 Reflection confocal microscopy for quantitative assessment of airway surface liquid dysregulation and pharmacological rescue in cystic fibrosis under near-physiological conditions

Agircan, A. S.; Lampe, M.; Scheuermann, H.; Albrecht, T.; Graeber, S. Y.; Balazs, A.; Baumann, I.; Block, S.; Pepperkok, R.; Mall, M. A.; Duerr, J.

10.1101/2024.03.05.583496 — cell biology — Posted on 2024-03-06

4161 DERIVATION OF ELEPHANT INDUCED PLURIPOTENT STEM CELLS

Appleton, E. M.; Hong, K.; Rodriguez, C.; Tanaka, Y.; Ashkenazy-Titelman, A.; Bhide, K.; Rasmussen-Ivey, C.; Ambriz-Pena, X.; Korover, N.; Bai, H.; Quieroz, A.; Nelson, J.; Rathod, G.; Knox, G.; Morgan, M.; Malviya, N.; Zhang, K.; Kehler, J.; Kowalczyk, A.; Bow, A.; McLendon, B.; Cantarel, B. L.; James, M.; Mason, C. E.; Gray, C.; Koehler, K.; Pearson, V.; Lamm, B.; Church, G.; Hysolli, E.

10.1101/2024.03.05.583606 — cell biology — Posted on 2024-03-06

4162 Matrix viscoelasticity controls epithelial cell mechanobiology through dimensionality

Ciccone, G.; Oliva, M. A. G.; Versaevel, M.; Cantini, M.; Vassalli, M.; Salmeron-Sanchez, M.; Gabriele, S.

10.1101/2024.03.05.583526 — biophysics — Posted on 2024-03-06

4163 Liebenberg syndrome severity arises from variations in Pitx1 locus topology and ectopically transcribing cells

Bompadre, O.; Rouco, R.; Darbellay, F.; Rauseo, A.; Guerard-Millet, F.; Gentile, C.; Kmita, M.; Andrey, G.

10.1101/2024.03.04.582675 — developmental biology — Posted on 2024-03-06

4164 Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome

Curinha, A.; Huang, Z.; Anglen, T.; Strong, M. A.; Gliech, C. R.; Jewett, C. E.; Friskes, A.; Holland, A. J.

10.1101/2024.03.06.583733 — cell biology — Posted on 2024-03-06

4165 Nucleolar stress induced the formation of a nucleolar stress body via the NOSR-1/NUMR-1 axis in Caenorhabditis elegans

Hong, M.; Guang, S.

10.1101/2024.03.05.583293 — cell biology — Posted on 2024-03-06

4166 Ultraviolet B acts as a dietary restriction mimetic by targeting mitochondrial bioenergetics.

Martirosyan, A.; Li, Y.; Woitzat, Y.; Lee, S.; Fu, L.; Ermolaeva, M.

10.1101/2024.03.05.583543 — cell biology — Posted on 2024-03-06

4167 Vitrification by high pressure freezing of a wide variety of sample using the HPM Live μ

Kodera, C.; Bret, Y.; Eyraud, F.; Heiligenstein, J.; Belle, M.; Heiligenstein, X.

10.1101/2024.03.06.583669 — cell biology — Posted on 2024-03-06

4168 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus

Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.

10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-06

4169 Under the radar: differential responses of bed bugs to an entomopathogen, environmental bacteria, and a human pathogen

Walt, H. K.; Bronzato-Badial, A.; Maedo, S. E.; Hinton, J. A.; King, J. G.; Pietri, J.; Hoffmann, F. G.

10.1101/2024.02.28.582586 — molecular biology — Posted on 2024-03-06

4170 Sorting at ciliary base and ciliary entry of BBSome, IFT-B and IFT-A

Mitra, A.; Gioukakis, E.; Mul, W.; Peterman, E.

10.1101/2024.03.05.583485 — molecular biology — Posted on 2024-03-06

4171 Forskolin reverses the O-GlcNAcylation dependent decrease in GABAAR current amplitude at hippocampal synapses possibly at a neurosteroid site on GABAARs.

Phillips, S.; Chatham, J.; McMahon, L.

10.1101/2024.03.06.583612 — neuroscience — Posted on 2024-03-06

4172 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.

Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.

10.1101/2023.12.07.570701 — biophysics — Posted on 2024-03-06

4173 'Drifting' Buchnera genomes track the microevolutionary trajectories of their aphid hosts

Thia, J. A.; Zhan, D.; Robinson, K.; Umina, P. A.; Hoffmann, A. A.; Yang, Q.

10.1101/2023.11.17.567149 — evolutionary biology — Posted on 2024-03-06

4174 The development of brain pericytes requires expression of the transcription factor nkx3.1 in intermediate precursors

Ahuja, S.; Adjekukor, C.; Li, Q.; Kocha, K. M.; Rosin, N.; Labit, E.; Sinha, S.; Narang, A.; Long, Q.; Biernaskie, J.; Huang, P.; Childs, S. J.

10.1101/2023.06.21.545941 — developmental biology — Posted on 2024-03-06

4175 Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction

Gao, X.; Zhang, B.; Liu, P.; Yuwen, M.; Liu, Z.; Tan, R.; Wang, B.; Liu, K.; Yang, Z.; Ba, J.; Bai, X.; Shama, S.; Tang, C.; Liu, L.; Zhu, C.; Wang, T.; Li, S.; Kang, J.

10.1101/2024.01.06.574490 — cell biology — Posted on 2024-03-06

4176 Chronic pharmacologic manipulation of dopamine transmission ameliorates metabolic disturbance in syndrome caused by mutated trappc9

Li, Y.; Usman, M.; Sapp, E.; Ke, Y.; Wang, Z.; Boudi, A.; DiFiglia, M.; Li, X.

10.1101/2024.02.13.580023 — neuroscience — Posted on 2024-03-06

4177 Cell class-specific electric field entrainment of neural activity

Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.

10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-03-06

4178 CRIPTO promotes extracellular vesicle uptake and activation of fibroblasts exposed to triple negative breast cancer cells

Freeman, D. W.; Gates, B. L.; Spendlove, M. D.; Gulbahce, H. E.; Spike, B. T.

10.1101/2024.03.01.583059 — cancer biology — Posted on 2024-03-06

4179 Gene count normalization in single-cell imaging-based spatially resolved transcriptomics

Atta, L.; Clifton, K.; Anant, M.; Aihara, G.; Fan, J.

10.1101/2023.08.30.555624 — bioinformatics — Posted on 2024-03-06

4180 Decoding Stability and Epistasis in Human Myoglobin by Deep Mutational Scanning and Codon-level Machine Learning

Kueng, C.; Protsenko, O.; Vanella, R.; Nash, M.

10.1101/2024.02.24.581358 — bioengineering — Posted on 2024-03-06

4181 Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

Ravala, S. K.; Adame-Garcia, S. R.; Li, S.; Chen, C.-L.; Cianfrocco, M. A.; Gutkind, J. S.; Cash, J. N.; Tesmer, J. J. G.

10.1101/2023.09.15.557836 — biochemistry — Posted on 2024-03-06

4182 Clustering and visualization of single-cell RNA-seq data using path metrics

Manousidaki, A.; Little, A.; Xie, Y.

10.1101/2021.12.14.472627 — genomics — Posted on 2024-03-06

4183 Demographic Consequences of Damage Dynamics in Single-Cell Ageing

Tugrul, M.; Steiner, U. K.

10.1101/2023.05.23.538602 — evolutionary biology — Posted on 2024-03-06

4184 Evaluating diversionary feeding as a method to resolve conservation conflicts in a recovering ecosystem.

Bamber, J.; Kortland, K.; Sutherland, C.; Payo-Payo, A.; Lambin, X.

10.1101/2023.11.09.566200 — ecology — Posted on 2024-03-06

4185 An isogenic E. coli population gives rise to multiple persister phenotypes

Rahman, K. M. T.; Amaratunga, R.; Singh, A.; Hossain, T.; Butzin, N. C.

10.1101/2023.12.09.570944 — microbiology — Posted on 2024-03-06

4186 High-parameter phenotypic characterization reveals a subset of human Th17 cells that preferentially produce IL17 against M. tuberculosis antigen.

Ogongo, P.; Tran, A.; Marzan, F.; Gingrich, D.; Krone, M.; Aweeka, F.; Lindestam Arlehamn, C. S.; Martin, J. N.; Deeks, S.; Hunt, P. W.; Ernst, J. D.

10.1101/2023.01.06.523027 — immunology — Posted on 2024-03-06

4187 Predictions enable top-down pattern separation in the macaque face-processing hierarchy

Nigam, T.; Schwiedrzik, C. M.

10.1101/2023.10.02.560497 — neuroscience — Posted on 2024-03-06

4188 SleepEEGpy: a Python-based software 'wrapper' package to organize preprocessing, analysis, and visualization of sleep EEG data

Belonosov, G.; Falach, R.; Schmidig, F. J.; Aderka, M.; Zhelezniakov, V.; Shani-Hershkovich, R.; Bar, E.; Nir, Y.

10.1101/2023.12.17.572046 — neuroscience — Posted on 2024-03-06

4189 Computational and neural mechanisms underlying the influence of action affordances on value learning

Yi, S.; O'Doherty, J. P.

10.1101/2023.07.21.550102 — neuroscience — Posted on 2024-03-06

4190 Sequence modeling and design from molecular to genome scale with Evo

Nguyen, E.; Poli, M.; Durrant, M. G.; Thomas, A. W.; Kang, B.; Sullivan, J.; Ng, M. Y.; Lewis, A.; Patel, A.; Lou, A.; Ermon, S.; Baccus, S. A.; Hernandez-Boussard, T.; Re, C.; Hsu, P. D.; Hie, B. L.

10.1101/2024.02.27.582234 — synthetic biology — Posted on 2024-03-06

4191 Evaluating polarizable biomembrane simulations against experiments

Kav, B.; Antila, H. S.; Dixit, S.; Miettinen, M. S.; Madsen, J. J.; Ollila, O. H. S.

10.1101/2023.12.01.569661 — biophysics — Posted on 2024-03-06

4192 Structure-based discovery of positive allosteric modulators for the calcium sensing receptor

Liu, F.; Wu, C.-G.; Tu, C.-L.; Glenn, I.; Meyerowitz, J.; Kaplan, A. L.; Lyu, J.; Cheng, Z.; Tarkhanova, O. O.; Moroz, Y. S.; Irwin, J. J.; Chang, W.; Shoichet, B. K.; Skiniotis, G.

10.1101/2023.12.27.573448 — biophysics — Posted on 2024-03-06

4193 From populations to pan-genomes: investigating the role of ecology and genomic architecture in maintaining species boundaries in the porcini mushroom, Boletus edulis

Tremble, K.; Brejon Lamartiniere, E.; Bradshaw, A. J.; Flores Arzu, R.; Hoffman, J. I.; Dentinger, B.

10.1101/2023.09.05.556370 — evolutionary biology — Posted on 2024-03-06

4194 Temporally resolved early BMP-driven transcriptional cascade during human amnion specification

Sekulovski, N.; Wettstein, J. C.; Carleton, A. E.; Juga, L. N.; Taniguchi, L. E.; Ma, X.; Rao, S.; Kropp Schmidt, J.; Golos, T.; Lin, C.-W.; Taniguchi, K.

10.1101/2023.06.19.545574 — developmental biology — Posted on 2024-03-06

4195 An Aurora kinase A-BOD1L1-PP2A B56 Axis promotes chromosome segregation fidelity

Kucharski, T.; Vlasac, I.; Higgs, M.; Christensen, B.; Bechstedt, S.; Compton, D. A.

10.1101/2023.08.06.552174 — cell biology — Posted on 2024-03-06

4196 The activation of INF2 by Piezo1/Ca2+ is required for mesenchymal to amoeboid transition in confined environments

Kar, N.; Caruso, A. P.; Prokopiou, N.; Logue, J. S.

10.1101/2023.06.23.546346 — cell biology — Posted on 2024-03-06

4197 Identification of KIFC1 as a putative vulnerability in lung cancers with centrosome amplification

Zhang, C.; Wu, B.; Wu, Y. F.; di Ciano-Oliveira, C.; Soria-Bretones, I.; Pham, N.-A.; Elia, A. J.; Chari, R.; Lam, W. L.; Bray, M. R.; Mak, T. W.; Tsao, M.-S.; Cescon, D. W.; Thu, K. L.

10.1101/2024.01.09.574105 — cancer biology — Posted on 2024-03-06

4198 Cryo-EM structure of the tetra-phosphorylated R-domain in Ycf1 reveals key interactions for transport regulation

de Carvalho, R. S. A.; Rasel, M. S. I.; Khandelwal, N. K.; Tomasiak, T. M.

10.1101/2024.03.06.583773 — biochemistry — Posted on 2024-03-06

4199 Molecular mechanism of α-latrotoxin action

Klink, B. U.; Alavizargar, A.; Subramaniam, K. K.; Chen, M.; Heuer, A.; Gatsogiannis, C.

10.1101/2024.03.06.583760 — biochemistry — Posted on 2024-03-06

4200 IMPROVING ALPHAFOLD2 PERFORMANCE WITH A GLOBAL METAGENOMIC & BIOLOGICAL DATA SUPPLY CHAIN

Munsamy, G.; Bohnuud, T.; Lorenz, P.

10.1101/2024.03.06.583325 — genomics — Posted on 2024-03-06

4201 Overlapping binding sites underlie TF genomic occupancy

Khetan, S.; Bulyk, M. L.

10.1101/2024.03.05.583629 — molecular biology — Posted on 2024-03-06

4202 Catalytically inactive SHP1-C453S mutant gain of "robust LLPS" function

Zhang, Q.; Sun, T.; Chen, Q.; Du, Y.; Kong, X.; Zhu, G.

10.1101/2024.03.06.583685 — molecular biology — Posted on 2024-03-06

4203 Effect of the terminal phosphate group on negative-ion CID/HCD fragmentation behaviors of RNA oligonucleotides

Zuo, M.-Q.; Song, G.; Dong, M.-Q.; Sun, R.-X.

10.1101/2024.03.05.583607 — molecular biology — Posted on 2024-03-06

4204 Sortase A-based Post-Translational Modifications on Encapsulin Nanocompartments

Helalat, S. H.; Sun, Y.; Tellez, R.

10.1101/2024.03.05.583518 — molecular biology — Posted on 2024-03-06

4205 Venomics and Peptidomics of Palearctic vipers: Clade-wide analysis of seven taxa of the genera Vipera, Montivipera, Macrovipera and Daboia across Türkiye

Damm, M.; Karis, M.; Petras, D.; Nalbantsoy, A.; Göcmen, B.; Süssmuth, R. D.

10.1101/2024.03.04.583389 — molecular biology — Posted on 2024-03-06

4206 CD47 is Required for Mesenchymal Progenitor Proliferation and Fracture Repair

Zondervan, R. L.; Capobianco, C. A.; Jenkins, D. C.; Reicha, J. D.; Fredrick, L. M.; Lam, C.; Isenberg, J. S.; Ahn, J.; Marcucio, R. S.; Hankenson, K. D.

10.1101/2024.03.06.583756 — molecular biology — Posted on 2024-03-06

4207 Structure of a Ca2+ bound phosphoenzyme intermediate in the inward-to-outward transition of Ca2+-ATPase 1 from Listeria monocytogenes

Hansen, S. B.; Flygaard, R. K.; Kjaergaard, M.; Nissen, P.

10.1101/2024.03.06.583647 — molecular biology — Posted on 2024-03-06

4208 Human immunodeficiency virus-1 induces and targets host genomic R-loops for viral genome integration

Park, K.; Lee, D.; Jeong, J.; Lee, S.; Kim, S.; Ahn, K.

10.1101/2024.03.06.583715 — molecular biology — Posted on 2024-03-06

4209 Evolution of Tn4371 family ICE; traR mediated coordination of cargo gene upregulation and horizontal transfer

Matsumoto, S.; Kishida, K.; Nonoyama, S.; Sakai, K.; Tsuda, M.; Nagata, Y.; Ohtsubo, Y.

10.1101/2024.03.05.583556 — molecular biology — Posted on 2024-03-06

4210 Effect of phage variation on Shiga toxin 2 (Stx2) production and the virulence of Stx-producing Escherichia coli

Nakamura, K.; Nakayama-Imaohji, H.; Emmanuel, M.; Taniguchi, I.; Gotoh, Y.; Isobe, J.; Kimata, K.; Igawa, Y.; Kitahashi, T.; Takahashi, Y.; Nomoto, R.; Iwabuchi, K.; Morimoto, Y.; Iyoda, S.; Kuwahara, T.; Hayashi, T.

10.1101/2024.03.06.583675 — microbiology — Posted on 2024-03-06

4211 The transition from a non-westernized to westernized gut microbiome in Indian-Immigrants and Indo-Canadians is associated with dietary acculturation

D'Aloisio, L. D.; Haskey, N.; Abulizi, N.; Karimianghadim, R.; Liu, C.; Chowdary, S.; Siva, L.; Vasudevan, S.; Shetty, V.; Bhaumik, U.; Ballal, M.; Howlader, D. R.; Pakpour, S.; Ghosh, S.; Barnett, J.; Gibson, D. L.

10.1101/2024.03.04.582285 — microbiology — Posted on 2024-03-06

4212 Adaptation of a methanogen to the constructed environment

Kawaichi, S.; Kotoky, R.; Fiutowski, J.; Rotaru, A.-E.

10.1101/2024.03.06.583737 — microbiology — Posted on 2024-03-06

4213 Strategies for Genetic Manipulation of the Halotolerant Black Yeast H. werneckii: Ectopic DNA integration and marker-free CRISPR/Cas9 Trasformation

Hernandez-Rodriguez, Y.; Bullard, A. M.; Busch, R. J.; Vargas-Muniz, J. M.

10.1101/2024.03.06.583723 — microbiology — Posted on 2024-03-06

4214 Unraveling and quantifying "Candidatus Saccharibacteria": in silico and experimental evaluation of V3-V4 16S rRNA metagenomics and qPCR protocols

Papaleo, S.; Nodari, R.; Sterzi, L.; D'Auria, E. C.; Cattaneo, C.; Bettoni, G.; Bonaiti, C.; Pagliarini, E.; Zuccotti, G. V.; Panelli, S.; Comandatore, F.

10.1101/2024.03.06.583507 — microbiology — Posted on 2024-03-06

4215 The microbiome of the lichen Lobaria pulmonaria varies according to climate in Europe

Bogale, A. T.; Braun, M.; Bernhardt, J.; Zuehlke, D.; Schiefelbein, U.; Bog, M.; Scheidegger, C.; Zengerer, V.; Becher, D.; Grube, M.; Riedel, K.; Bengtsson, M. M.

10.1101/2024.03.06.583579 — microbiology — Posted on 2024-03-06

4216 Erg251 has complex and pleiotropic effects on azole susceptibility, filamentation, and stress response phenotypes

Zhou, X.; Hilk, A.; Solis, N. V.; Hogan, B. M.; Bierbaum, T. A.; Filler, S. G.; Burrack, L. S.; Selmecki, A.

10.1101/2024.03.06.583770 — microbiology — Posted on 2024-03-06

4217 Targeting G9a translational mechanism of SARS-CoV-2 pathogenesis for multifaceted therapeutics of COVID-19 and its sequalae

Muneer, A.; Xie, L.; Xie, X.; Zhang, F.; Wrobel, J.; Yan, X.; Yu, X.; Wang, C.; Gheorghe, C.; Wu, P.; Song, J.; Ming, G.-L.; Jin, J.; Song, H.; Shi, P.-Y.; Chen, X.

10.1101/2024.03.04.583415 — immunology — Posted on 2024-03-06

4218 Rare Variable M. tuberculosis Antigens induce predominant Th17 responses in human infection

Ogongo, P.; Wassie, L.; Tran, A.; Columbus, D.; Sharling, L.; Ouma, G.; Ouma, S. G.; Bobosha, K.; Lindestam Arlehamn, C. S.; Gandhi, N. R.; Auld, S. C.; Rengarajan, J.; Day, C. L.; Altman, J. D.; Blumberg, H.; Ernst, J. D.

10.1101/2024.03.05.583634 — immunology — Posted on 2024-03-06

4219 Early cytokine-driven adaptation of survival pathways in lymphoid cells during targeted therapies

Luo, M.-X.; Tan, T.; Trussart, M.; Poch, A.; Nguyen, M. H. T.; Speed, T. P.; Hicks, D. G.; Bandala-Sanchez, E.; Peng, H.; Chappaz, S.; Slade, C.; Utzschneider, D. T.; Strasser, A.; Thijssen, R.; Ritchie, M. E.; Tam, C. S.; Lindeman, G.; Huang, D. C.; Lew, T. E.; Anderson, M. A.; Roberts, A. W.; Teh, C. E.; Gray, D. H.

10.1101/2024.03.04.583422 — cancer biology — Posted on 2024-03-06

4220 MORTALITY-ASSOCIATED SARS-COV-2 GENOMIC VARIANTS FROM PATIENTS HOSPITALIZED FOR SEVERE PNEUMONIA IN AGUASCALIENTES, MEXICO FROM 2020 TO 2023

Gomez, B. M.; Gamboa, M. L.; Marmolejo, A. P.; Ceapa, C. D.

10.1101/2024.03.05.583594 — molecular biology — Posted on 2024-03-06

4221 Regulation of virion production by the ORF8 signal peptide across SARS-CoV-2 variants

Khalid, M. M.; Chen, I.; Soveg, F. S.; Taha, T. Y.; Tabata, T.; Suryawanshi, R.; Syed, A. M.; Ciling, A.; McCavitt-Malvido, M.; Schulze-Gahmen, U.; Hayashi, J.; Kim, I.-J.; Fong, S. W.; Batra, J.; Kumar, G. R.; Laurent, R.; NG, L. F.; Krogan, N. J.; Doudna, J. A.; Verdin, E.; Ott, M.

10.1101/2024.03.05.583578 — microbiology — Posted on 2024-03-06

4222 Enhanced Ca2+-Driven Arrhythmias in Female Patients with Atrial Fibrillation: Insights from Computational Modeling

Zhang, X.; Wu, Y.; Smith, C.; Louch, W. E.; Morotti, S.; Dobrev, D.; Grandi, E.; Ni, H.

10.1101/2024.03.04.583217 — physiology — Posted on 2024-03-06

4223 Deciphering Oxygen Distribution and Hypoxia Profiles in the Tumor Microenvironment: A Data-Driven Mechanistic Modeling Approach

Kumar, P.; Lacroix, M.; Dupre, P.; Arslan, J.; Fenou, L.; Orsetti, B.; Le Cam, L.; Racoceanu, D.; Radulescu, O.

10.1101/2024.03.04.583326 — cancer biology — Posted on 2024-03-06

4224 Past, present, and future spatial distributions of deep-sea coral and sponge microbiomes revealed by predictive models

Busch, K.; Murillo, F. J.; Lirette, C.; Wang, Z.; Kenchington, E.

10.1101/2024.03.04.583289 — ecology — Posted on 2024-03-06

4225 Immunomagneto-activated hepatocyte-specific tissue vesicle profiling reveals message diversification from regenerating liver

Ying, S.; Cao, Y.; Liu, L.; Zhou, Z.-K.; Luo, X.-Y.; Li, C.-H.; Chen, S.-Y.; Lei, X.; Xing, S.-J.; Shi, K.; Qiu, J.-Y.; Zhang, K.; Li, Y.-Y.; Zheng, C.-X.; Jin, F.; Sui, B.; Jin, Y.

10.1101/2024.03.03.583167 — cell biology — Posted on 2024-03-06

4226 Relative rDNA copy number is not associated with resistance training-induced skeletal muscle hypertrophy and does not affect myotube anabolism in vitro

Godwin, J. S.; Michel, J. M.; Ludlow, A. T.; Fruge, A. D.; Mobley, C. B.; Nader, G. A.; Roberts, M. D.

10.1101/2024.03.04.583417 — molecular biology — Posted on 2024-03-06

4227 Damage sensing through TLR9 Promotes Viral Clearance and Recovery During Influenza Infection

Kim, J.; Yuan, Y.; Agaronyan, K.; Zhao, A.; Wang, V. D.; Gupta, G.; Essayas, H.; Kaminski, A.; McGovern, J.; Yu, S.; Woo, S.; Lee, C. J.; Saleh, T.; Hu, B.; Sun, Y.; Ishikawa, G.; Bain, W.; Evankovich, J.; Herzog, E.; Dela Cruz, C. S.; Ryu, C.; Sharma, L.

10.1101/2024.03.04.583378 — immunology — Posted on 2024-03-06

4228 Task interference as a neuronal basis for the cost of cognitive flexibility

Xue, C.; Markman, S. K.; Chen, R.; Kramer, L. E.; Cohen, M. R.

10.1101/2024.03.04.583375 — neuroscience — Posted on 2024-03-06

4229 Lateral olivocochlear neurons modulate cochlear responses to noise exposure

Sitko, A.; Frank, M.; Romero, G.; Goodrich, L.

10.1101/2024.03.04.583418 — neuroscience — Posted on 2024-03-06

4230 Hyaluronidase impacts exposures of long-acting injectable paliperidone palmitate in rodent models

Pertinez, H.; Kaushik, A.; Curley, P.; Arshad, U.; El-Khateeb, E.; Li, S.-Y.; Tasneen, R.; Sharp, J.; Kijak, E.; Herriott, J.; Neary, M.; Noe, M.; Flexner, C.; Nuermberger, E.; Owen, A.; Ammerman, N. C.

10.1101/2024.03.03.583160 — pharmacology and toxicology — Posted on 2024-03-06

4231 The p90 Ribosomal S6 Kinases 2 and 4 promote Prostate Cancer cell proliferation in androgen-dependent and independent ways

Cronin, R.; Azadova, A.; Marco, A.; Laissue, P. P.; Brooke, G. N.; Prischi, F.

10.1101/2024.03.04.582739 — cancer biology — Posted on 2024-03-06

4232 LDL-Binding IL-10 Reduces Vascular Inflammation in Atherosclerotic Mice

Volpatti, L. R.; Norton de Matos, S.; Borjas, G.; Reda, J.; Watkins, E. A.; Zhou, Z.; Nguyen, M.; Solanki, A.; Fang, Y.; Hubbell, J. A.

10.1101/2024.03.04.582839 — bioengineering — Posted on 2024-03-06

4233 Mitochondrial dynamics regulate cell size in the developing cochlea

O'Sullivan, J. D.; Terry, S.; Scott, C. A.; Bullen, A.; Jagger, D. J.; Mann, Z. F.

10.1101/2024.03.04.583298 — developmental biology — Posted on 2024-03-06

4234 Cell-state dependent regulation of PPARγ signaling by ZBTB9 in adipocytes

Xu, X.; Charrier, A.; Congrove, S.; Buchner, D. A.

10.1101/2024.03.04.583402 — cell biology — Posted on 2024-03-06

4235 STRIPAK controls cell-cell communication by promoting cytoneme biogenesis through the membrane-sculpting function of Slik.

Rambaud, B.; Joseph, M.; Tsai, F.-C.; De Jamblinne, C. V.; Del Guidice, E.; Sabelli, R.; Bassereau, P.; Hipfner, D. R.; Carreno, S.

10.1101/2024.03.04.583182 — cell biology — Posted on 2024-03-06

4236 Deep learning methods to forecasting human embryo development in time-lapse videos

Sharma, A.; Dorobantiu, A.; Ali, S.; Iliceto, M.; Stensen, M. H.; Delbarre, E.; Riegler, M. A.; Hammer, H. L.

10.1101/2024.03.04.583269 — cell biology — Posted on 2024-03-06

4237 The sodium-proton exchangers sNHE and NHE1 control plasma membrane hyperpolarization in mouse sperm.

Novero, A. G.; Rodriguez, P. T.; de la Vega Beltran, J. L.; Schiavi-Ehrenhaus, L. J.; Luque, G. M.; Carruba, M.; Stival, C.; Gentile, I.; Ritagliati, C.; Santi, C. M.; Nishigaki, T.; Krapf, D.; Buffone, M. G.; Darszon, A.; Trevino, C. L.; Krapf, D.

10.1101/2024.03.04.583310 — cell biology — Posted on 2024-03-06

4238 Reconstitution of the uterine immune milieu after transplantation

Strunz, B.; Ivarsson, M.; Sun, D.; Ziegenhain, C.; Crona Guterstam, Y.; Solders, M.; Bjorklund, A.; Marquardt, N.; Kaipe, H.; Floter-Radestad, A.; Brusell-Gidlof, S.; Brannstrom, M.; Bjorkstrom, N. K.

10.1101/2024.03.04.583277 — immunology — Posted on 2024-03-06

4239 Distinct prelimbic cortex neuronal responses to emotional states of others drive emotion recognition in adult male mice

Jabarin, R.; Mohapatra, A. N.; Ray, N.; Netser, S.; Wagner, S.

10.1101/2024.03.03.583184 — neuroscience — Posted on 2024-03-06

4240 Feature-independent Encoding of Visual Salience inthe Mouse Superior Colliculus

Wu, R.; Xu, J.; Li, C.; Zhang, Z.; Li, L.-y.; Li, Y.

10.1101/2024.03.04.583246 — neuroscience — Posted on 2024-03-06

4241 Loss of Esr1 Does Not Affect Hearing and Balance

Simms, S. S.; Milani, M.; Kim, M.-J.; Husain, R. M.; Infante, L. P.; Cooke, P. S.; Someya, S.

10.1101/2024.03.03.583163 — neuroscience — Posted on 2024-03-06

4242 Medial prefrontal dopamine dynamics reflect allocation of selective attention

Melugin, P. R.; Nolan, S. O.; Kandov, E.; Ferrara, C. F.; Farahbakhsh, Z. Z.; Siciliano, C. A.

10.1101/2024.03.04.583245 — neuroscience — Posted on 2024-03-06

4243 Application of Cancer Cell Line Encyclopedia for Measuring Correlation Between Transcriptomics and Proteomics as a Guide for System-level Insights

Williams, B.; Perry, D.; Aspesi, P.; Parker, J.; Johnson, T.; Su, W.; Tabacman, E.; Delisle, K.; Avishan, K.; Myer, V.; Mapa, F.; Hinterberg, M.; Williams, A.; Jennings, L.; Janjic, N.; Loureiro, J.

10.1101/2024.03.03.583123 — systems biology — Posted on 2024-03-06

4244 PFKP regulates AXL-MET oncogenic and metabolic pathways in lung cancer

Sun, Y.; Zhao, H.; Feng, H.; Liu, Y.; Li, Y.; Chen, S.; Zhou, Z.; Du, Y.; Zeng, X.; Ren, H.; Su, W.; Mei, Q.; Chen, G.

10.1101/2024.03.03.583230 — cancer biology — Posted on 2024-03-06

4245 Spatial Transcriptomics of Spinal Ependymoma in NF2-related Schwannomatosis

Burket, N. J.; Wang, J.; Gao, H. J.; Bell, R.; Zhang, C.; Liu, Y.; Clapp, W.; Tailor, J. K.

10.1101/2024.03.03.583240 — cancer biology — Posted on 2024-03-06

4246 PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer

Bagchi, A.; Bhattacharya, A.; Chatterji, U.; BISWAS, A.

10.1101/2024.03.03.583221 — cancer biology — Posted on 2024-03-06

4247 RGS10 deficiency facilitates distant metastasis by inducing epithelial-mesenchymal transition in breast cancer

Liu, Y.; Jiang, Y.; Qiu, P.; Ma, T.; Bu, J.; Hu, Y.; Jin, M.; Zhu, T.; Gu, X.

10.1101/2024.03.04.583283 — cancer biology — Posted on 2024-03-06

4248 Subtomogram averaging of helical filaments in cryo-electron tomography

Zhang, X.; Mahamid, J.

10.1101/2024.03.04.583254 — biophysics — Posted on 2024-03-06

4249 GDOP: A graph convolutional network-based drug "on-target" pathway prediction algorithm

Wu, X.; Zhang, L.; Zheng, M.

10.1101/2024.03.03.583216 — bioinformatics — Posted on 2024-03-06

4250 Knotted artifacts in predicted 3D RNA structures

Gren, B. A.; Antczak, M.; Zok, P.; Sulkowska, J. I.; Szachniuk, M.

10.1101/2024.03.04.583268 — bioinformatics — Posted on 2024-03-06

4251 GenoTriplo: A SNP genotype calling method for triploids

Roche, J.; Besson, M.; Allal, F.; Haffray, P.; Patrice, P.; Vandeputte, M.; Phocas, F.

10.1101/2024.03.03.583188 — bioinformatics — Posted on 2024-03-06

4252 Improved synthesis and application of an alkyne-functionalized isoprenoid analogue to study the prenylomes of motor neurons, astrocytes and their stem cell progenitors

Suazo, K.; Mishra, V.; Maity, S.; Auger, S.; Justyna, K.; Petre, A.; Ottoboni, L.; Ongaro, J.; Corti, S.; Lotti, F.; Przedborski, S.; Distefano, M. D.

10.1101/2024.03.03.583211 — biochemistry — Posted on 2024-03-06

4253 Matrix game between full siblings in Mendelian populations

Garay, J.; Varga, T.; Csiszar, V.; F. Mori, T.; Szilagyi, A.

10.1101/2024.03.04.583267 — evolutionary biology — Posted on 2024-03-06

4254 Multi-Temporal Remote Sensing of Inland Surface Waters: A Fusion of Sentinel-1 Data Applied to Small Seasonal Ponds in Semiarid Environments

Valerio, F.; Godinho, S.; Ferraz, G.; Pita, R.; Gameiro, J.; Silva, B.; Marques, A. T.; Silva, J. P.

10.1101/2024.03.03.583180 — ecology — Posted on 2024-03-06

4255 Vegetative stage and soil horizon respectively determine direction and magnitude of rhizosphere priming effects in contrasting treeline soils

Michel, J.; Fontaine, S.; Revaillot, S.; Picon-Cochard, C.; Whitaker, J.

10.1101/2024.03.03.582814 — ecology — Posted on 2024-03-06

4256 Quantitative Superresolution Imaging of F-Actin in the Cell Body and Cytoskeletal Protrusions Using Phalloidin-Based Single-Molecule Labeling and Localization Microscopy

Gunasekara, H.; Perera, T.; Chao, C.-J.; Bruno, J.; Saed, B.; Anderson, J.; Zhao, Z.; Hu, Y. S.

10.1101/2024.03.04.583337 — cell biology — Posted on 2024-03-06

4257 Combining function and structure in a single macro-scale connectivity model of the human brain

Sairanen, V.

10.1101/2024.03.03.583186 — neuroscience — Posted on 2024-03-06

4258 A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice

Lu, S.; Portela, I. D. J.; Martino, N.; Ramos, R. B.; Salinero, A.; Smith, R.; Zuloaga, K. L.; Adam, A. P.

10.1101/2024.03.03.583191 — neuroscience — Posted on 2024-03-06

4259 Closed-loop auditory stimulation targeting alpha and theta oscillations during REM sleep induces phase-dependent power and frequency changes

Jaramillo, V.; Hebron, H.; Wong, S.; Atzori, G.; Bartsch, U.; Dijk, D.-J.; Violante, I. R.

10.1101/2024.03.03.582907 — neuroscience — Posted on 2024-03-06

4260 PCSK9 deficiency promotes the development of peripheral neuropathy

Jaafar, A. K.; Paulo-Ramos, A.; Rastoldo, G.; Veeren, B.; Planesse, C.; Bringart, M.; Rondeau, P.; Lambert, G.; Meilhac, O.; Bourane, S.

10.1101/2024.03.03.583154 — neuroscience — Posted on 2024-03-06

4261 Deep Learning Models for Atypical Serotoninergic Cells Recognition

Corradetti, D.; Bernardi, A.; Corradetti, R.

10.1101/2024.03.03.583157 — neuroscience — Posted on 2024-03-06

4262 A unique subset of pericystic endothelium associates with aberrant microvascular remodelling and impaired blood perfusion early in polycystic kidney disease

Jafree, D. J.; Perera, C.; Ball, M.; Tolomeo, D.; Pomeranz, G.; Wilson, L.; Davis, B.; Mason, W. J.; Funk, E. M.; Kolatsi-Joannou, M.; Polschi, R.; Malik, S.; Stewart, B. J.; Price, K. L.; Mitchell, H.; Motallebzadeh, R.; Muto, Y.; Lees, R.; Needham, S. R.; Moulding, D.; Chandler, J. C.; Walsh, C. L.; Woolf, A. S.; Winyard, P. J.; Scambler, P. J.; Hagerling, R.; Clatworthy, M. R.; Humphreys, B.; Lythgoe, M. F.; Walker-Samuel, S.; Long, D. A.

10.1101/2024.03.03.583132 — pathology — Posted on 2024-03-06

4263 Integration of pH control into Chi.Bio reactors and demonstration with small-scale enzymatic poly(ethylene terephthalate) hydrolysis

Denton, M. C.; Murphy, N. P.; Norton-Baker, B.; Lua, M.; Steel, H.; Beckham, G. T.

10.1101/2024.03.03.582641 — bioengineering — Posted on 2024-03-06

4264 Investigation of protein imprinted gelatin/N-Vinylformamide hydrogel membrane protein grafted on polyurethane

Mikautadze, O.; Chkheidze, D.; Kotishadze, T.; Surguladze, M.

10.1101/2024.03.03.583225 — bioengineering — Posted on 2024-03-06

4265 Prevalent fast evolution of genes involved in heterochromatin functions

Lin, L.; Huang, Y.; McIntyre, J.; Chang, C.-H.; Colmenares, S. S.; Lee, G. Y. C.

10.1101/2024.03.03.583199 — evolutionary biology — Posted on 2024-03-06

4266 Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity

Tejero, J.; Hesterberg, R.; Drapela, S.; Ilter, D.; Raizada, D.; Lazure, F.; Kashfi, H.; Liu, M.; Fernandez-Garcia, J.; Fendt, S.-M.; Asara, J.; Cleveland, J.; Gomes, A. P.

10.1101/2024.03.03.583124 — immunology — Posted on 2024-03-06

4267 Maternal cannabis use alters excitatory inputs to corticostriatal efferent neurons in rat offspring

Ginder, D. E.; Weimar, H. V.; Lindberg, J. E. M.; Fisher, Z. D. G.; Lim, M. M.; Peters, J. H.; McLaughlin, R. J.

10.1101/2024.03.03.583210 — neuroscience — Posted on 2024-03-06

4268 Whole-brain neural substrates of behavioral variability in the larval zebrafish

Manley, J.; Vaziri, A.

10.1101/2024.03.03.583208 — neuroscience — Posted on 2024-03-06

4269 Individualized fMRI neuromodulation enhances visuospatial perception: a guided approach targeted towards the neuro-rehabilitation of cortical blindness and deceleration of subjective cognitive impairment.

Allam, A. K. R.; Allam, V. R.; Reddy, S.; Patel, A.; Froudarakis, E. R.; Rohren, E. M.; Sheth, S.; Papageorgiou, T. D.

10.1101/2024.03.03.582390 — neuroscience — Posted on 2024-03-06

4270 Opioid receptor expressing neurons of the central amygdala gate behavioral effects of ketamine in mice

Pomrenze, M. B.; Vaillancourt, S.; Llorach, P.; Rijsketic, D. R.; Casey, A. B.; Gregory, N.; Salgado, J. S.; Malenka, R. C.; Heifets, B. D.

10.1101/2024.03.03.583196 — neuroscience — Posted on 2024-03-06

4271 Prediction of Ca2+ binding site in proteins with a fast and accurate method based on statistical mechanics and analysis of crystal structures

Basit, A.; Choudhury, D.; Bandyopadhyay, P.

10.1101/2024.03.03.583063 — biophysics — Posted on 2024-03-06

4272 The immune map of human body

Gan, R.; Jin, X.; Ren, X.

10.1101/2024.03.03.583227 — bioinformatics — Posted on 2024-03-06

4273 Does What You Eat Affect How You Mate? Disentangling the Interactions Between Diet-Induced Phenotypic Plasticity and Adult Reproductive Strategies in Black Soldier Flies.

Zhang, Q.-H.; Ng, K. H.; Chin, W. S.; Tang, Y. J.; Lin, J.; Puniamoorthy, N.

10.1101/2024.03.03.583236 — evolutionary biology — Posted on 2024-03-06

4274 IPPK-1 and IP6 contribute to ventral nerve cord assembly in C. elegans

Noblett, N.; Roenspies, T.; Flibotte, S.; Colavita, A.

10.1101/2024.03.03.583222 — developmental biology — Posted on 2024-03-06

4275 The telencephalon is a neuronal substrate for systemic inflammatory responses in teleosts via polyamine metabolism

Mani, A.; Haddad, F.; Barreda, D.; Salinas, I.

10.1101/2024.03.03.583242 — immunology — Posted on 2024-03-06

4276 Causal Brain Network Evaluates Surgical Outcomes in Patients with Drug-Resistant Epilepsy: A Retrospective Comparative Study

Wang, Y.; Lin, W.; Liu, M.

10.1101/2024.03.03.583165 — neuroscience — Posted on 2024-03-06

4277 Unethical amnesia brain: Memory and metacognitive distortion induced by dishonesty

Xu, X. J.; Mobbs, D.; Wu, H.

10.1101/2024.03.03.583239 — neuroscience — Posted on 2024-03-06

4278 Investigating the mode of action for liver toxicity and wasting-like responses produced by high dose exposures to longer chain perfluoroacid substances (PFAS) using high throughput transcriptomics

Barutcu, R.; Black, M.; Andersen, M. E.

10.1101/2024.03.02.583129 — pharmacology and toxicology — Posted on 2024-03-06

4279 Salidroside and its in vivo metabolite tyrosol could act directly on dopamine D2 receptors: a study using RNAseq combined with Connectivity Map analysis

Zhang, J.; Jiang, C.; Han, J.

10.1101/2024.03.03.583234 — pharmacology and toxicology — Posted on 2024-03-06

4280 An Early Miocene skeleton of Brachydiceratherium Lavocat, 1951 (Mammalia, Perissodactyla) from the Baikal area, Russia, and a revised phylogeny of Eurasian teleoceratines

Sizov, A.; Klementiev, A.; Antoine, P.-O.

10.1101/2022.07.06.498987 — paleontology — Posted on 2024-03-06

4281 Spiking GABAergic OPC tumor cells prolong survival in IDH1 mutant glioma

10.1101/2024.03.02.583026 — cancer biology — Posted on 2024-03-06

4282 Development of a Bipyrimidineamide based α-Helix Mimetic Lead Compound for efficient Targeting of MDM2 in Triple-Negative Breast Cancer

On, J. L.; Woloschin, V.; Gier, F.; Tu, J.-W.; Bhatia, S.; Lenz, T.; Stühler, K.; Niederacher, D.; Neubauer, H.; Fehm, T.; Kurz, T.; Esser, K.

10.1101/2024.03.02.582899 — cancer biology — Posted on 2024-03-06

4283 Conformational landscape of soluble α-klotho revealed by cryogenic electron microscopy

Schnicker, N. J.; Xu, Z.; Amir, M.; Gakhar, L.; Huang, C.-L.

10.1101/2024.03.02.583144 — biophysics — Posted on 2024-03-06

4284 Comparison of Synergy Extrapolation and Static Optimization for Estimating Multiple Unmeasured Muscle Activations during Walking

Ao, D.; Fregly, B. J.

10.1101/2024.03.03.583228 — biophysics — Posted on 2024-03-06

4285 Examination of the role of mutualism in immune evasion

Gourmet, L. E.; Mallick, P.; Walker-Samuel, S.

10.1101/2024.03.02.583098 — bioinformatics — Posted on 2024-03-06

4286 Transformer-Based Deep Learning Model with Latent Space Regularization for CRISPR-Cas Protein Sequence Classification

Nammi, B.; Madugula, S. S.; Pujar, P.; Arachchige, V.; Lui, J.; Wang, S.

10.1101/2024.03.02.583136 — bioinformatics — Posted on 2024-03-06

4287 Unsupervised generative AI discovers pan-leukocyte dysregulated pathways in single-cell lupus data

Bolouri, H.; Cerosaletti, K.; Lacy-Hulbert, A.

10.1101/2024.03.02.583143 — bioinformatics — Posted on 2024-03-06

4288 Leveraging Single-Cell Sequencing to Classify and Characterize Tumor Subgroups in Bulk RNA-Sequencing Data

Shetty, A.; Wang, S.; Khan, A. B.; English, C. W.; Nouri, S. H.; Magill, S. T.; Raleigh, D. R.; Klisch, T. J.; Harmanci, A. O.; Patel, A. J.; Serin Harmanci, A.

10.1101/2024.03.02.583114 — bioinformatics — Posted on 2024-03-06

4289 Gcoupler: An AI-enhanced tool unveiled Endogenous Intracellular Allosteric Modulators of Evolutionary Conserved GPCR-Gα Interface

10.1101/2023.02.14.528587 — bioinformatics — Posted on 2024-03-06

4290 EpicTope: narrating protein sequence features to identify non-disruptive epitope tagging sites

Zinski, J.; Chung, H.; Joshi, P.; Warrick, F.; Berg, B. D.; Glova, G.; McGrail, M. A.; Balciunas, D.; Friedberg, I.; Mullins, M. C.

10.1101/2024.03.03.583232 — developmental biology — Posted on 2024-03-06

4291 Thymic dendritic cell-derived IL-27p28 promotes the establishment of functional bias against IFN-γ production in newly generated CD4+ T cells through STAT1-related epigenetic mechanisms

Zhang, J.; Tang, H.; Wu, H.; Pang, X.; Jin, R.; Zhang, Y.

10.1101/2024.03.02.583138 — immunology — Posted on 2024-03-06

4292 Spatial attention alters visual cortical representation during target anticipation

Tuncok, E.; Carrasco, M.; Winawer, J.

10.1101/2024.03.02.583127 — neuroscience — Posted on 2024-03-06

4293 A worldwide ENIGMA study on epilepsy-related gray and white matter compromise across the adult lifespan

Chen, J.; Ngo, A.; Rodriguez-Cruces, R.; Royer, J.; Caligiuri, M. E.; Gambardella, A.; Concha, L.; Keller, S. S.; Cendes, F.; Yasuda, C. L.; Alvim, M. K. M.; Bonilha, L.; Gleichgerrcht, E.; Focke, N. K.; Kreilkamp, B.; Domin, M.; von Podewils, F.; Langner, S.; Rummel, C.; Wiest, R.; Martin, P.; Kotikalapudi, R.; Bender, B.; O'Brien, T. J.; Sinclair, B.; Vivash, L.; Kwan, P.; Desmond, P. M.; Lui, E.; Duma, G. M.; Bonanni, P.; Ballerini, A.; Vaudano, A. E.; Meletti, S.; Tondelli, M.; Alhusaini, S.; Doherty, C. P.; Cavalleri, G. L.; Delanty, N.; Kälviäinen, R.; Jackson, G.; Kowalczyk, M.; Masca

10.1101/2024.03.02.583073 — neuroscience — Posted on 2024-03-06

4294 Temporal interference electrical neurostimulation yields fMRI BOLD activation in humans

Modak, P.; Fine, J.; Colon, B.; Need, E.; Hulvershorn, L.; Finn, P.; Brown, J.

10.1101/2024.03.02.583125 — neuroscience — Posted on 2024-03-06

4295 Olfactory bulb stimulation mitigates Alzheimer-like disease progression

Raoufy, M. R.; Salimi, M.; Shahsavar, P.; Dehghan, S.; Javan, M.; Mirnajafi Zadeh, J.; Nazari, M.

10.1101/2024.03.03.583116 — neuroscience — Posted on 2024-03-06

4296 Adult Neurogenesis Reconciles Flexibility and Stability of Olfactory Perceptual Memory

Sakelaris, B.; Riecke, H.

10.1101/2024.03.03.583153 — neuroscience — Posted on 2024-03-06

4297 Investigating the mode of action for wasting produced by tetrachlorodibenzo-p-dioxin (TCDD) in rats using transcriptomics: Evidence for roles of AHR and ARNT in circadian cycling

Andersen, M. E.; Barutcu, R.; Black, M. B.; Harrill, J.

10.1101/2024.03.02.583130 — pharmacology and toxicology — Posted on 2024-03-06

4298 2.5D Actuating Substrates Enable Decoupling the Mechanical and Biochemical Effects of Muscle Exercise on Motor Neurons

Bu, A.; Afghah, F.; Castro, N.; Bawa, M.; Kohli, S.; Shah, K.; Rios, B.; Butty, V.; Raman, R.

10.1101/2024.03.02.583091 — bioengineering — Posted on 2024-03-06

4299 Haplotype-resolved karyotype construction from Hi-C data using refLinker

Brunette, G. J.; Tourdot, R. W.; Wangsa, D.; Pellman, D.; Zhang, C.-Z.

10.1101/2024.03.02.583108 — genomics — Posted on 2024-03-06

4300 A universal niche geometry governs the response of ecosystems to environmental perturbations

Goyal, A.; Rocks, J. W.; Mehta, P.

10.1101/2024.03.02.583107 — ecology — Posted on 2024-03-06

4301 Metabolic rate and foraging behaviour: A mechanistic link across body size and temperature gradients

Shokri, M.; Cozzoli, F.; Basset, A.

10.1101/2024.03.02.583052 — ecology — Posted on 2024-03-06

4302 Nutrient loading from a sustainably certified aquaculture operation dwarfs annual nutrient inputs from a large multi-use watershed, Lake Yojoa, Honduras

Fadum, J.; Ross, M.; Tenorio, E.; Barby, C.; Hall, E.

10.1101/2024.03.02.583117 — ecology — Posted on 2024-03-06

4303 Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

Kodba, S.; Oztop, A.; van Berkum, E.; Iwanski, M. K.; Nijenhuis, W.; Kapitein, L. C.; Chaigne, A.

10.1101/2024.03.06.583686 — cell biology — Posted on 2024-03-06

4304 Tofacitinib uptake by patient-derived intestinal organoids predicts individual clinical responsiveness

Jang, K. K.; Ercelen, D.; Cen Feng, J. Y. C.; Gurunathan, S.; Zhou, C.; Korman, A.; Newell, L.; Hudesman, D.; Jones, D. R.; Loke, P.; Axelrad, J. E.; Cadwell, K.

10.1101/2024.03.02.583137 — cell biology — Posted on 2024-03-06

4305 The CCR4/CCL17 axis drives intestinal acute Graft versus Host disease after allogeneic bone marrow transplantation

Schlaweck, S.; Klesse, M.; Schanz, O.; Jorch, S. K.; Kristiansen, G.; Toma, M.; Flores, C.; Becker-Gotot, J.; Kurts, C.; Brossart, P.; Wolf, D.; Heine, A.

10.1101/2024.03.02.583093 — immunology — Posted on 2024-03-06

4306 Crimean-Congo Hemorrhagic Fever Survivors Elicit Protective Non-Neutralizing Antibodies that Target 11 Overlapping Regions on Viral Glycoprotein GP38

Shin, O. S.; Monticelli, S. R.; Hjorth, C. K.; Hornet, V.; Doyle, M.; Abelson, D.; Kuehne, A. I.; Wang, A.; Bakken, R. R.; Mishra, A. K.; Middlecamp, M.; Champney, E.; Stuart, L.; Maurer, D. P.; Li, J.; Berrigan, J. L.; Balinandi, S.; Lutwama, J. J.; Lobel, L.; Zeitlin, L.; Walker, L. M.; Dye, J. M.; Chandran, K.; Herbert, A. S.; Pauli, N. T.; McLellan, J. S.

10.1101/2024.03.02.583110 — immunology — Posted on 2024-03-06

4307 Giardia intestinalis reshapes mucosal immunity toward a Type 2 response that attenuates inflammatory bowel-like diseases

Sardinha-Silva, A.; Gazzinelli-Guimaraes, P. H.; Ajakaye, O. G.; Ferreira, T. R.; Alves-Ferreira, E.; Tjhin, E. T.; Gregg, B.; Fink, M. Y.; Coelho, C. H.; Singer, S. M.; Grigg, M. E.

10.1101/2024.03.02.583119 — immunology — Posted on 2024-03-06

4308 Automated identification and quantification of stereotypical movements from video recordings of children with ASD

Barami, T.; Manelis-Baram, L.; Kaiser, H.; Ilan, M.; Slobodkin, A.; Hadashi, O.; Hadad, D.; Waissengreen, D.; Nitzan, T.; Menashe, I.; Michaelovsky, A.; Begin, M.; Zachor, D.; Sadaka, Y.; Koler, J.; Zagdon, D.; Meiri, G.; Azencot, O.; Sharf, A.; Dinstein, I.

10.1101/2024.03.02.582828 — neuroscience — Posted on 2024-03-06

4309 Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe

Donkels, C.; Huber, S.; Demerath, T.; Scheiwe, C.; Schah, M. J.; Heers, M.; Urbach, H.; Schulze-Bonhage, A.; Prinz, M.; Haeussler, U.; Vlachos, A.; Beck, J.; Nakagawa, J. M.; Haas, C. A.

10.1101/2024.03.02.582894 — neuroscience — Posted on 2024-03-06

4310 IL6 mediated cFLIP downregulation increases the migratory and invasive potential of triple negative breast cancer cells

Sinha, S.; Roy, R.; Barman, N.; Sarkar, P.; Saha, A.; Biswas, N.

10.1101/2024.01.14.575471 — cancer biology — Posted on 2024-03-06

4311 Resistance to PSEN1-selective γ-secretase inhibitors in T-cell acute lymphoblastic leukemia

Vandersmissen, C.; Demeyer, S.; Jacobs, K.; Boogaerts, L.; Fernandez, S. G.; Segers, H.; Chavez-Gutierrez, L.; Cools, J.

10.1101/2024.03.01.582944 — cancer biology — Posted on 2024-03-06

4312 CHEMOKINE SIGNALING IN BREAST CANCER: FOCUS ON CC-MOTIF CHEMOKINE LIGANDS

Kacar, S.

10.1101/2024.03.01.583061 — cancer biology — Posted on 2024-03-06

4313 HER2 Prognostic Significance and Therapeutic Implications in Gastric Cardia Adenocarcinoma: Insights from Multi-Omics Profiling

Wang, L.; Xing, p.; Zhao, X.; Song, X.; Wei, M.; Lei, L.; Xu, R.; Wang, R.; Ma, L.; You, D.; Chen, P.; Xie, M.; Zhao, M.; Zhang, H.; Lv, H.; Li, A.; Wang, X.; Zhou, F.; Gao, S.; Chen, X.

10.1101/2024.03.02.583089 — cancer biology — Posted on 2024-03-06

4314 A Transformer Based Machine Learning of Molecular Grammar Inherent in Proteins Prone to Liquid Liquid Phase Separation

Wasim, A.; Mondal, J.

10.1101/2024.03.02.583105 — biophysics — Posted on 2024-03-06

4315 Characterization of Composite Agarose-Collagen Hydrogels for Chondrocyte Culture

Zigan, C.; Benito Alston, C.; Chatterjee, A.; Solotio, L.; Chan, D. D.

10.1101/2024.03.02.583023 — bioengineering — Posted on 2024-03-06

4316 Assessing the impact of Brd2 depletion on chromatin compartmentalization

Athreya, A.; Xie, L.; Tjian, R.; Zhang, B.; Liu, Z. J.

10.1101/2024.03.02.583085 — genomics — Posted on 2024-03-06

4317 Investigating the effects of protons versus x-rays on radiation-induced lymphopenia after brain irradiation

Coupey, J.; Pham, T. N.; Toutain, J.; Ivanova, V.; HUE, E.; Helaine, C.; Ismail, A.; Saulnier, R.; Simonin, G.; Rousseau, M.; Moignier, C.; Thariat, J.; Valable, S.

10.1101/2024.03.02.583088 — cell biology — Posted on 2024-03-06

4318 Misspellings or miscellings- non-verifiable cell lines in cancer research publications

Oste, D. J.; Pathmendra, P.; Richardson, R. A. K.; Johnson, G.; Ao, Y.; Arya, M. D.; Enochs, N. R.; Hussein, M.; Kang, J.; Lee, A.; Danon, J. J.; Cabanac, G.; Labbe, C.; Capes Davis, A.; Stoeger, T.; Byrne, J. A.

10.1101/2024.02.29.582220 — cancer biology — Posted on 2024-03-06

4319 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences

Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.

10.1101/2024.03.05.583455 — microbiology — Posted on 2024-03-06

4320 Staphylococcal sRNA IsrR down-regulates methylthiotransferase MiaB under iron-deficient conditions

Barrault, M.; Leclair, E.; Jacquet, E.; Bouloc, P.

10.1101/2023.11.09.566390 — microbiology — Posted on 2024-03-06

4321 Altered X-chromosome inactivation predisposes to autoimmunity

Huret, C.; Ferraye, L.; David, A.; Mohamed, M.; Valentin, N.; Charlotte, F.; Savignac, M.; Goodhardt, M.; Guery, J.-C.; Rougeulle, C.; Morey, C.

10.1101/2023.04.20.537662 — immunology — Posted on 2024-03-06

4322 Glutamatergic Supramammillary Nucleus Neurons Respond to Threatening Stressors and Promote Active Coping

Escobedo, A.; Holloway, S.-A.; Votoupal, M.; Cone, A. L.; Skelton, H. E.; Legaria, A.; Ndiokho, I.; Floyd, T.; Kravitz, A. V.; Bruchas, M. R.; Norris, A. J.

10.1101/2022.09.22.507167 — neuroscience — Posted on 2024-03-06

4323 Molecular evaluation of Conogethes punctiferalis (Guenee, 1854): Species status and intraspecific divergence

An, J.; Yao, Y.-L.; Gao, P.; Xiu, M.; Shi, C.-M.

10.1101/2023.10.28.564482 — zoology — Posted on 2024-03-06

4324 Interpretable Machine Learning Decodes Soil Microbiome's Response to Drought Stress

Hagen, M.; Dass, R.; Westhues, C.; Blom, J.; Schultheiss, S. S.; Patz, S.

10.1101/2023.11.30.569182 — bioinformatics — Posted on 2024-03-06

4325 Circulating Small Extracellular Vesicle RNA Profiling for the Detection of T1a stage Colorectal Cancer and Precancerous Advanced Adenoma

Min, L.; Bu, F.; Meng, J.; Liu, X.; Guo, Q.; Zhao, L.; Li, Z.; Li, X.; Zhu, S.; Zhang, S.

10.1101/2023.06.04.543604 — bioinformatics — Posted on 2024-03-06

4326 Chloramphenicol reduces phage resistance evolution by suppressing bacterial cell surface mutants

Parab, L.; Romeyer Dherbey, J.; Rivera, N.; Schwarz, M.; Bertels, F.

10.1101/2023.08.28.552763 — evolutionary biology — Posted on 2024-03-06

4327 Individual genotype but not phenotype predicts river migration success in Atlantic salmon

Moccetti, P.; Bolland, J. D.; Adams, C. E.; Rodger, J. R.; Honkanen, H. M.; Newton, M.; Lothian, A. J.; Nunn, A. D.; Joyce, D. A.

10.1101/2023.08.15.553252 — evolutionary biology — Posted on 2024-03-06

4328 Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

Li, A.; Yi, J.; Li, X.; Dong, L.; Ostrow, L. W.; Ma, J.; Zhou, J.

10.1101/2023.02.12.528218 — cell biology — Posted on 2024-03-06

4329 Ilamycin E and ilamycin F are dual inhibitors of ClpX and ClpC1 in mycobacteria

Gao, Y.; Fang, C.; Zhou, B.; Hameed, H. M. A.; Sun, C.; Tian, X.; He, J.; Han, X.; Zhang, H.; Ju, J.; Chen, X.; Zhong, N.; Ma, J.; Xiong, X.; Zhang, T.

10.1101/2024.02.24.581832 — microbiology — Posted on 2024-03-06

4330 Hetero-antagonism of avibactam and sulbactam with cefiderocol in carbapenem-resistant Acinetobacter spp.

Wong, O.; Mezcord, V.; Lopez, C.; Traglia, G. M.; Pasteran, F.; Tuttobene, M. R.; Corso, A.; Tolmasky, M.; Bonomo, R. A.; Ramirez, M. S.

10.1101/2024.03.04.583376 — microbiology — Posted on 2024-03-06

4331 Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome

Lambert, G. S.; Rice, B. L.; Kaddis Maldonado, R. J.; Chang, J.; Parent, L. J.

10.1101/2024.01.18.575255 — microbiology — Posted on 2024-03-06

4332 The structure of an Amyloid Precursor Protein/talin complex indicates a mechanical basis of Alzheimer's Disease.

Ellis, C.; Ward, N. L.; Rice, M.; Ball, N. J.; Lambert, J.-C.; Chapuis, J.; Goult, B. T.

10.1101/2024.03.04.583202 — neuroscience — Posted on 2024-03-06

4333 The use of threshold methods to detect beta bursts may inadequately characterize the beta band

Langford, Z. D.; Wilson, C. R.

10.1101/2023.12.15.571838 — neuroscience — Posted on 2024-03-06

4334 Macrophage mediated mesoscale brain mechanical homeostasis mechanically imaged via optical tweezers and Brillouin microscopy in vivo

So, W. Y.; Johnson, B.; Gordon, P. B.; Bishop, K. S.; Gong, H.; Burr, H. A.; Staunton, J. R.; Handler, C.; Sood, R.; Scarcelli, G.; Tanner, K.

10.1101/2023.12.27.573380 — biophysics — Posted on 2024-03-06

4335 Raw signal segmentation for estimating RNA modifications and structures from Nanopore direct RNA sequencing data

Cheng, G.; Vehtari, A.; Cheng, L.

10.1101/2024.01.11.575207 — bioinformatics — Posted on 2024-03-06

4336 Multicore-fiber microendoscopy for functional cellular in-organ imaging

Dancker, T. A.; Elhawy, M. I.; Rittershauss, R.; Tian, Q.; Schwarz, Y.; Hoffmann, M. D. A.; Carlein, C.; Wyatt, A.; Wahl, V.; Speyerer, D.; Kandah, A.; Boehm, U.; Prates Roma, L.; Bruns, D.; Lipp, P.; Krasteva-Christ, G.; Lauterbach, M. A.

10.1101/2024.03.02.583077 — bioengineering — Posted on 2024-03-06

4337 Functional Mapping of Movement and Speech Using Task-Based Electrophysiological Changes in Stereoelectroencephalography

Jensen, M. A.; Fine, A.; Kerezoudis, P.; Wong-Kisiel, L.; Alden, E.; Hermes, D.; Miller, K. J.

10.1101/2024.02.29.582865 — neuroscience — Posted on 2024-03-06

4338 Intermittent stimulation of the basal forebrain improves working memory in aged nonhuman primates.

Wang, Z.; Pennington, K. R.; Debs, L.; Chung, S.; Bava, J. M.; Garin, C.; Vale, F. L.; Bick, S. K.; Englot, D. J.; Terry, A. V.; Constantinidis, C.; Blake, D. T.

10.1101/2024.03.01.582925 — neuroscience — Posted on 2024-03-06

4339 Microbe tree metabolite interactions in the soil - phyllosphere continuum of poplar tree: when microbes rewire poplar root exudate and metabolome

Fracchia, F.; Guinet, F.; Engle, N.; Tschaplinski, T.; Veneault-Fourrey, C.; Deveau, A.

10.1101/2024.03.04.583280 — plant biology — Posted on 2024-03-06

4340 Large-scale single-cell profiling of stem cells uncovers redundant regulators of shoot development and yield trait variation

Xu, X.; Passalacqua, M.; Rice, B.; Demesa-Arevalo, E.; Kojima, M.; Takebayashi, Y.; Harris, B.; Sakakibara, H.; Gallavotti, A.; Gillis, J.; Jackson, D.

10.1101/2024.03.04.583414 — plant biology — Posted on 2024-03-06

4341 Protein Embeddings Predict Binding Residues in Disordered Regions

Jahn, L. R.; Marquet, C.; Heinzinger, M.; Rost, B.

10.1101/2024.03.05.583540 — bioinformatics — Posted on 2024-03-06

4342 AMP-Diffusion: Integrating Latent Diffusion with Protein Language Models for Antimicrobial Peptide Generation

Chen, T.; Vure, P.; Pulugurta, R.; Chatterjee, P.

10.1101/2024.03.03.583201 — bioinformatics — Posted on 2024-03-06

4343 Engineering a wolf spider A-family toxin towards increased antimicrobial activity but low toxicity

Dersch, L.; Stahlhut, A.; Eichberg, J.; Paas, A.; Hardes, K.; Vilcinskas, A.; Lueddecke, T.

10.1101/2024.03.04.583312 — bioengineering — Posted on 2024-03-06

4344 High-Throughput Phenotyping of Seed Quality Traits Using Imaging and Deep Learning in Dry Pea

Morales, M.; Worral, H.; Piche, L.; Atanda, S. A.; Dariva, F.; Ramos, C.; Hoang, K.; Yan, C.; Flores, P.; Bandillo, N.

10.1101/2024.03.05.583564 — plant biology — Posted on 2024-03-06

4345 Cis inhibition of co-expressed DIPs and Dprs shapes neural development

Morano, N. C.; Lopez, D. S.; Meltzer, H.; Sergeeva, A. P.; Katsamba, P. S.; Gupta, H. P.; Becker, J. E.; Bornstein, B.; Cosmanescu, F.; Schuldiner, O.; Mann, R. S.; Honig, B.; Shapiro, L.

10.1101/2024.03.04.583391 — biochemistry — Posted on 2024-03-06

4346 Changes of urinary proteome in rats after intragastric administration of zinc gluconate

Shen, Z.; Yang, M.; Wang, H.; Gao, Y.

10.1101/2024.03.04.583149 — biochemistry — Posted on 2024-03-06

4347 A novel sulfatase for acesulfame degradation in wastewater treatment plants as evidenced from Shinella strains

Ding, C.; Rohwerder, T.; Liu, Y.; Bonatelli, M. L.; Von Postel, T.; Kleinsteuber, S.; Adrian, L.

10.1101/2024.03.04.583314 — genomics — Posted on 2024-03-06

4348 Accurate prediction of site- and amino-acid substitution rates with a mutation-selection model

Andre, I.

10.1101/2024.03.02.583099 — evolutionary biology — Posted on 2024-03-06

4349 Comparative analysis of Wolbachia maternal transmission and localization in host ovaries

Hague, M. T. J.; Wheeler, T. B.; Cooper, B. S.

10.1101/2024.03.03.583170 — evolutionary biology — Posted on 2024-03-06

4350 A Spatial Multi-Modal Dissection of Host-Microbiome Interactions within the Colitis Tissue Microenvironment

Zhu, B.; Bai, Y.; Yeo, Y. Y.; Lu, X.; Rovira-Clave, X.; Chen, H.; Yeung, J.; Gerber, G. K.; Angelo, M.; Shalek, A. K.; Nolan, G. P.; Jiang, S.

10.1101/2024.03.04.583400 — immunology — Posted on 2024-03-06

4351 Biolearn, an open-source library for biomarkers of aging

Ying, K.; Paulson, S.; Perez-Guevara, M.; Emamifar, M.; Casas Martinez, M.; Kwon, D.; Poganik, J. R.; Moqri, M.; Gladyshev, V. N.

10.1101/2023.12.02.569722 — bioinformatics — Posted on 2024-03-06

4352 Predicting Phylogenetic Bootstrap Values viaMachine Learning

Wiegert, J.; Haag, J.; Hoehler, D.; Stamatakis, A.

10.1101/2024.03.04.583288 — bioinformatics — Posted on 2024-03-06

4353 DUAL: deep unsupervised simultaneous simulation and denoising for cryo-electron tomography

Zeng, X.; Ding, Y.; Zhang, Y.; Uddin, M.; Dabouei, A.; Xu, M.

10.1101/2024.03.02.583135 — bioinformatics — Posted on 2024-03-06

4354 Improved selection of canonical proteins for reference proteomes

Insana, G.; Martin, M. J.; Pearson, W. R.

10.1101/2024.03.04.583387 — bioinformatics — Posted on 2024-03-06

4355 Deep5hmC: Predicting genome-wide 5-Hydroxymethylcytosine landscape via a multimodal deep learning model

Ma, X.; Sai, S. R.; Zhao, F.; Yao, B.; Wen, Z.; Jin, P.; Zhao, J.; Chen, L.

10.1101/2024.03.04.583444 — bioinformatics — Posted on 2024-03-06

4356 NFixDB (Nitrogen Fixation DataBase) - A Comprehensive Integrated Database for Robust 'Omics Analysis of Diazotrophs

Bellanger, M.; Figueroa, J. L.; Tiemann, L.; Friesen, M. L.; White, R. A.

10.1101/2024.03.04.583350 — bioinformatics — Posted on 2024-03-06

4357 Multi-Scale Protein Language Model for Unified Molecular Modeling

Zheng, K.; Long, S.; Lu, T.; Yang, J.; Dai, X.; Zhang, M.; Nie, Z.; Ma, W.-Y.; Zhou, H.

10.1101/2024.03.04.583284 — bioinformatics — Posted on 2024-03-06

4358 High-fidelity annotated genome of the polyploid and quarantine root-knot nematode, Meloidogyne enterolobii

Poullet, M.; Gopal, H.; Rancurel, C.; Sallaberry, M.; Lopez-Roques, C.; Lledo, J.; Kiewnick, S.; Danchin, E. G. J.

10.1101/2024.03.01.582926 — genomics — Posted on 2024-03-06

4359 First report of astroviruses in Tanzanian bats

Joffrin, L.; Iliopoulou, E.; Falzon, M.; Sabuni, C.; Kirkpatrick, L.; De Bruyn, L.

10.1101/2024.03.05.581362 — molecular biology — Posted on 2024-03-06

4360 Transmission-blocking activity of artesunate, chloroquine and methylene blue on Plasmodium vivax gametocytes.

Chaumeau, V.; Wasisakun, P.; Watson, J. A.; Oo, T.; Aryalamloed, S.; Sue, M. P.; Htoo, G. N.; Tha, N. M.; Archusuksan, L.; Sawasdichai, S.; Gornsawun, G.; Mehra, S.; White, N. J.; Nosten, F.

10.1101/2024.02.18.580875 — microbiology — Posted on 2024-03-06

4361 Multi-conflict islands are a widespread trend within Serratia spp

Cummins, T.; Garrett, S. R.; Blower, T. R.; Mariano, G.

10.1101/2024.01.28.577318 — microbiology — Posted on 2024-03-06

4362 Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes

Alempic, J.-M.; Bisio, H.; Villalta, A.; Santini, S.; Lartigue, A.; Schmitt, A.; Bugnot, C.; Notaro, A.; BELMUDES, L.; Adrait, A.; Poirot, O.; Ptchelkine, D.; De Castro, C.; Coute, Y.; Abergel, C.

10.1101/2023.04.28.538727 — microbiology — Posted on 2024-03-06

4363 The Magic Impacts of Sounds on Consumer's Brain: How Do Natural Sounds Nudge Green Product Purchase?

Liang, G.; Wang, Y.

10.1101/2024.02.29.582721 — neuroscience — Posted on 2024-03-06

4364 Manifold Learning Uncovers Nonlinear Interactions between the Adolescent Brain and the Social Environment in Predicting Mental Health Problems

Busch, E. L.; Conley, M. I.; Baskin-Sommers, A.

10.1101/2024.02.29.582854 — neuroscience — Posted on 2024-03-06

4365 Widespread neural and autonomic system synchrony across the brain-body axis

Bolt, T. S.; Wang, S.; Nomi, J. S.; Setton, R.; Gold, B.; Frederick, B.; Chen, J. J.; Picchioni, D.; Spreng, R. N.; Keilholz, S.; Uddin, L.; Chang, C.

10.1101/2023.01.19.524818 — neuroscience — Posted on 2024-03-06

4366 Quantifying Harmony between Direct and Indirect Pathways in The Basal Ganglia; Healthy and Parkinsonian States

Kim, S.-Y.; Lim, W.

10.1101/2023.09.19.558549 — neuroscience — Posted on 2024-03-06

4367 Predicting the Beat Bin - Beta Oscillations Predict the Envelope Sharpness in a Rhythmic Sequence

Leske, S.; Endestad, T.; Volehaugen, V.; Foldal, M. D.; Blenkmann, A. O.; Solbakk, A.-K.; Danielsen, A.

10.1101/2023.07.21.550020 — neuroscience — Posted on 2024-03-06

4368 Sex-specific behavioral features of juvenile and adult haploinsufficient Scn2a+/- female mice, model of Autism Spectrum Disorder

Marcantonio, W.; Simonti, M.; Lena, I.; Mantegazza, M.

10.1101/2023.12.11.571165 — neuroscience — Posted on 2024-03-06

4369 SleepEEGpy: a Python-based software 'wrapper' package to organize preprocessing, analysis, and visualization of sleep EEG data

Belonosov, G.; Falach, R.; Schmidig, F. J.; Aderka, M.; Zhelezniakov, V.; Shani-Hershkovich, R.; Bar, E.; Nir, Y.

10.1101/2023.12.17.572046 — neuroscience — Posted on 2024-03-06

4370 An enduring role for hippocampal pattern completion in addition to an emergent non-hippocampal contribution to holistic episodic retrieval after a 24-hour delay

Joensen, B.; Ashton, J.; Berens, S. C.; Gaskell, G.; Horner, A. J.

10.1101/2023.09.15.557911 — neuroscience — Posted on 2024-03-06

4371 Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

Kamei, K.-i. F.; Kobayashi-Kirschvink, K. J.; Nozoe, T.; Nakaoka, H.; Umetani, M.; Wakamoto, Y.

10.1101/2023.05.09.539921 — systems biology — Posted on 2024-03-06

4372 Sci-comm "behind the scenes": Gendered narratives of scientific outreach activities in the life sciences

Beasley-Hall, P. G.; Papadelos, P.; Hewitt, A.; Lassaline, C. R.; Umbers, K. D. L.; Guzik, M. T.

10.1101/2024.02.28.582614 — scientific communication and education — Posted on 2024-03-06

4373 Biological Control of Green Mold in Simulated Post-harvest Chain of Citrus Fruit: Efficacy of Candida oleophila Strain O and Molecular Insight into Elicitation of Host Immune System

Rovetto, E. I.; La Spada, F.; El Boumlasy, S.; Conti Taguali, S.; Riolo, M.; Pane, A.; Cacciola, S. O.

10.1101/2024.03.05.583495 — plant biology — Posted on 2024-03-06

4374 PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration

Chen, J.; Holt, J. R.; Evans, E. L.; Lowengrub, J. S.; Pathak, M. M.

10.1101/2022.10.13.512181 — biophysics — Posted on 2024-03-06

4375 SCI-VCF: A cross-platform GUI solution to Summarise, Compare, Inspect, and Visualise the Variant Call Format

Kamaraj, V.; Sinha, H.

10.1101/2023.08.09.552664 — bioinformatics — Posted on 2024-03-06

4376 Non-viral Intron Knockins Enable Simplified and Flexible Targeting of Endogenous Genes

Roth, T. L.; Lu, J.; McClellan, A.; Takacsi-Nagy, O.; Satpathy, A. L.

10.1101/2024.03.05.582227 — bioengineering — Posted on 2024-03-06

4377 A robust method for measuring aminoacylation through tRNA-Seq

Davidsen, K.; Sullivan, L. B.

10.1101/2023.07.31.551363 — biochemistry — Posted on 2024-03-06

4378 Reconstitution of cytolinker-mediated crosstalk between actin and vimentin

Isturiz Petitjean, I.; Tran, Q. D.; Goutou, A.; Kabir, Z.; Wiche, G.; Leduc, C.; Koenderink, G. H.

10.1101/2023.10.27.564417 — biochemistry — Posted on 2024-03-06

4379 PyBrOpS: a Python package for breeding program simulation and optimization for multi-objective breeding

Shrote, R. Z.; Thompson, A. M.

10.1101/2023.02.10.528043 — genetics — Posted on 2024-03-06

4380 Resource or slot model in visual working memory: Are they different?

Hojjati, F.; Motahharynia, A.; Adibi, A.; Adibi, I.; Sanayei, M.

10.1101/2024.02.08.579494 — neuroscience — Posted on 2024-03-06

4381 Scaling Properties for Artificial Neural Network Models of a Small Nervous System

Simeon, Q.; Venancio, L. R.; SKUHERSKY, M.; Nayebi, A.; Boyden, E. S.; Yang, G.

10.1101/2024.02.13.580186 — neuroscience — Posted on 2024-03-06

4382 Linking reduced prefrontal microcircuit inhibition in schizophrenia to EEG biomarkers in silico

Rosanally, S.; Mazza, F.; Yao, H. K.; Hay, E.

10.1101/2023.08.11.553052 — neuroscience — Posted on 2024-03-06

4383 Particulate Contamination of Human Placenta: Plastic and Non-Plastic

Zurub, R. W.; Bainbridge, S. A.; Rahman, L.; Halappanavar, S.; Wade, M.

10.1101/2024.03.01.583005 — physiology — Posted on 2024-03-06

4384 High-throughput genetics enables identification of nutrient utilization and accessory energy metabolism genes in a model methanogen

Day, L. A.; Carlson, H. K.; Fonseca, D. R.; Arkin, A. P.; Price, M. N.; Deutschbauer, A.; Costa, K.

10.1101/2024.03.05.583561 — microbiology — Posted on 2024-03-05

4385 Chrom-pro: A User-Friendly Toolkit for De-novo Chromosome Assembly and Genomic Analysis

Song, W.; Ye, T.; Liu, S.; Shen, D.; Du, Y.; Yang, Y.; Lu, Y.; Jin, H.; huo, y.; Piao, W.; Jin, H.

10.1101/2024.03.02.583079 — bioinformatics — Posted on 2024-03-05

4386 Non-viral Intron Knockins Enable Simplified and Flexible Targeting of Endogenous Genes

Roth, T. L.; Lu, J.; McClellan, A.; Takacsi-Nagy, O.; Satpathy, A. L.

10.1101/2024.03.05.582227 — bioengineering — Posted on 2024-03-05

4387 Structural and biochemical characterization of an encapsulin-associated rhodanesefrom Acinetobacter baumannii

Benisch, R.; Giessen, T. W.

10.1101/2024.02.19.581022 — biochemistry — Posted on 2024-03-05

4388 Telomere-to-telomere genome assembly of a male goat reveals novel variants associated with cashmere traits

Wu, H.; Luo, L.-Y.; Zhang, Y.-H.; Zhang, C.-Y.; Huang, J.-H.; Mo, D.-X.; Zhao, L.-M.; Wang, Z.-X.; Wang, Y.-C.; EEr, H.-H.; Bai, W.-L.; Han, D.; Dou, X.-T.; Ren, Y.-L.; Dingkao, R.; Chen, H.-L.; Ye, Y.; Du, H.-D.; Zhao, Z.-Q.; Wang, X.-J.; Jia, S.-G.; Liu, Z.; Li, M.-H.

10.1101/2024.03.03.582909 — genomics — Posted on 2024-03-05

4389 Establishment of H3K9me3 is influenced by genomic context and is temporally uncoupled from signal growth during early zebrafish embryogenesis

Duval, K. L.; Artis, A. R.; Goll, M. G.

10.1101/2024.03.05.582530 — genetics — Posted on 2024-03-05

4390 Variety is the spice of life: nongenetic variation in life histories influences population growth and evolvability

Forsythe, A. B.; Otto, S. P.; Nelson, W. A.; Day, T.

10.1101/2024.03.02.583100 — evolutionary biology — Posted on 2024-03-05

4391 Evolved and plastic gene expression in adaptation to a novel niche

Steward, R. A.; Ortega Gimenez, J.; Choudhary, S.; Yi, S.; Aken, O. V.; Runemark, A.

10.1101/2024.03.02.583104 — evolutionary biology — Posted on 2024-03-05

4392 Meta-analysis of livestock effects on tree regeneration in oak agroforestry systems

Wadud, A. I.; Bugalho, M. N.; Vaz, P. G.

10.1101/2024.03.02.583097 — ecology — Posted on 2024-03-05

4393 Spatial visualization of A-to-I Editing in cells using Endonuclease V Immunostaining Assay (EndoVIA)

Quillin, A. L.; Arnould, B.; Knutson, S. D.; Heemstra, J. M.

10.1101/2024.03.04.583344 — molecular biology — Posted on 2024-03-05

4394 First report of astroviruses in Tanzanian bats

Joffrin, L.; Iliopoulou, E.; Falzon, M.; Sabuni, C.; Kirkpatrick, L.; De Bruyn, L.

10.1101/2024.03.05.581362 — molecular biology — Posted on 2024-03-05

4395 Development of Broad-spectrum β-cyclodextrins-Based Nanomaterials Against Influenza Viruses

Zwygart, A. C.-A.; Medaglia, C.; Zhu, Y.; Tarbet, E. B.; Westover, J. B.; Fage, C.; Le Roy, D.; Roger, T.; Constant, S.; Huang, S.; Stellacci, F.; Silva, P. J.; Tapparel, C.

10.1101/2024.03.05.583334 — microbiology — Posted on 2024-03-05

4396 Vividness of Visual Imagery Supported by Intrinsic Structural-Functional Brain Network Dynamics

Kvamme, T.; Lumaca, M.; Zana, B.; Paunovi, D.; Silvanto, J.; Sandberg, K.

10.1101/2024.03.02.582470 — neuroscience — Posted on 2024-03-05

4397 Circadian Rhythms in Murine Ocular Tissues including Sclera are affected by Neurobasal A Medium Preincubation, Mouse Strain, but not Sex

Milicevic, N.; Sandu, C.; Challet, E.; Ihalainen, T. O.; Nymark, S.; Felder-Schmittbuhl, M.-P.

10.1101/2024.03.01.583036 — neuroscience — Posted on 2024-03-05

4398 Emotion induction modulates neural dynamics during ideational originality

Khalil, R.; Fruhholz, S.; Godde, B.

10.1101/2024.03.02.583080 — neuroscience — Posted on 2024-03-05

4399 An immune signature of postoperative cognitive decline in elderly patients

Verdonk, F.; Cambriel, A.; Hedou, J.; Ganio, E.; Bellan, G.; Gaudilliere, D.; Einhaus, J.; Sabayev, M.; Stelzer, I. A.; Feyaerts, D.; Bonham, A. T.; Ando, K.; Choisy, B.; Drover, D.; Heifets, B.; Chretien, F.; Aghaeepour, N.; Angst, M. S.; Molliex, S.; Sharshar, T.; Gaillard, R.; Gaudilliere, B.

10.1101/2024.03.02.582845 — neuroscience — Posted on 2024-03-05

4400 Disease Modifying Osteoarthritis Drug Discovery Using A Temporal Phenotypic Reporter In Primary Human Chondrocytes

Cruz, M. A.; Gronowicz, S.; Karimzadeh, M.; Martyniak, K.; Medam, R.; Kean, T. J.

10.1101/2023.03.10.532073 — pharmacology and toxicology — Posted on 2024-03-05

4401 GenePT: A Simple But Effective Foundation Model for Genes and Cells Built From ChatGPT

Chen, Y. T.; Zou, J.

10.1101/2023.10.16.562533 — bioinformatics — Posted on 2024-03-05

4402 TALEN-mediated intron editing of HSPCs enables transgene expression restricted to the myeloid lineage

Seclen, E.; Jang, J. C.; Lawal, A. O.; Pulicani, S.; Boyne, A.; Tkach, D.; Juillerat, A.; Duchateau, P.; Valton, J.

10.1101/2024.03.05.583596 — bioengineering — Posted on 2024-03-05

4403 A complete mitochondrial genome of a Roman-era Plasmodium falciparum

Llanos-Lizcano, A.; Haemmerle, M.; Sperduri, A.; Sawyer, S.; Zagorc, B.; Ozdogan, K. T.; Cheronet, O.; Guellil, M.; Kuhlwilm, M.; Pinhasi, R.; Gelabert, P.

10.1101/2024.03.05.583465 — genomics — Posted on 2024-03-05

4404 Chromatin packing domains persist after RAD21 depletion in 3D.

Li, W. S.; Carter, L. M.; Almassalha, L. M.; Pujadas-Liwag, E. M.; Kuo, T.; MacQuarrie, K. L.; Carignano, M. A. M.; Dravid, V. P.; Kanemaki, M.; Szleifer, I. G.; Backman, V.

10.1101/2024.03.02.582972 — genomics — Posted on 2024-03-05

4405 Latent Evolutionary Signatures: A General Framework for Analyzing Music and Cultural Evolution

Warrell, J.; Salichos, L.; Gancz, M.; Gerstein, M.

10.1101/2020.10.23.352930 — evolutionary biology — Posted on 2024-03-05

4406 Nucleolar accumulation of APE1 through condensates is mediated by rRNA forming G-quadruplex structures

Dall Agnese, G.; Hannett, N. M.; Overholt, K. J.; Platt, J. M.; Henninger, J. E.; Marcos-Vidal, A.; Antoniali, G. E.; Tell, G.

10.1101/2024.03.04.583447 — molecular biology — Posted on 2024-03-05

4407 FMNL2 regulates actin for ER and mitochondria distribution in oocyte meiosis

Pan, M.-H.; Pan, Z.-N.; Sun, M.-H.; Li, X.-H.; Ju, J.-Q.; Luo, S.-M.; Ou, X.-H.; Sun, S.

10.1101/2023.10.05.561058 — developmental biology — Posted on 2024-03-05

4408 Modulating Cas13a trans-cleavage by double strand RNA: Application to the development of an autocatalytic sensor

Deng, F.; Gulati, S.; Sang, R.; Li, Y.; Goldys, E.

10.1101/2024.03.05.583472 — molecular biology — Posted on 2024-03-05

4409 Hairpin-locker mediated CRISPR/Cas tandem system for ultrasensitive detection of DNA without pre-amplification

Deng, F.; Sang, R.; Li, Y.; Yang, B.; Zhai, X.; Xue, R.; Zhang, C.; Deng, W.; Goldys, E. M.

10.1101/2024.03.05.583466 — molecular biology — Posted on 2024-03-05

4410 C9orf72 poly-PR condensation induces nuclear TDP-43 pathology and is inhibited by RNA in an optogenetic cell model

Hodgson, R. E.; Rayment, J.; Huang, W.-P.; Avila, A. S.; Shelkovnikova, T. A.

10.1101/2024.03.05.581933 — cell biology — Posted on 2024-03-05

4411 Rectal Swab DNA Collection Protocol for PCR Genotyping in Rats

Kaye, A. E.; Proctor-Bonbright, J. W.; Yu, J. Y.

10.1101/2024.03.02.583131 — molecular biology — Posted on 2024-03-05

4412 Reconciling the importance of minerals for propagation of antibiotic resistance genes in the environment

Hendiani, S.; Carbajo, C.; Hansen, M. F.; Agbaje, O.; Arellano, P.; Verma, T.; Mandic Mulec, I.; Burmoelle, M.; Sand, K. K.

10.1101/2024.03.04.583397 — microbiology — Posted on 2024-03-05

4413 Prophages block cell surface receptors to ensure survival of their viral progeny

Taylor, V. L.; Shah, M.; Patel, P. H.; Yusuf, A.; Burk, C. M.; Gitai, Z.; Davidson, A. R.; Koch, M. D.; Maxwell, K. L.

10.1101/2024.03.05.583538 — microbiology — Posted on 2024-03-05

4414 Spatial patterns of Hyalomma marginatum-borne pathogens in the Occitanie region (France), a focus on the intriguing dynamics of Rickettsia aeschlimannii

KUKLA, C. J.; Bernard, C.; Bru, D.; Galon, C.; Giupponi, C.; Huber, K.; Jourdan-Pineau, H.; Malandrin, L.; Rakotoarivony, I.; Riggi, C.; Vial, L.; Moutailler, S.; Pollet, T.

10.1101/2024.03.05.583534 — microbiology — Posted on 2024-03-05

4415 Yeast-based production platform for potent and stable heavy chain-only antibodies

Lonigro, C.; Eeckhaut, H.; Symakani, R. A.; Roose, K.; Schepens, B.; Sedeyn, K.; De Smet, A.-S.; Zavala Marchan, J. C.; Vanhaverbeke, P.; Vanmarcke, S.; Claes, K.; De Cae, S.; Demol, H.; Devos, S.; Fijalkowska, D.; Nerinckx, W.; Rossey, I.; Weyts, W.; Abdelnabi, R.; Jochmans, D.; Neyts, J.; Saelens, X.; van Schie, L.; Callewaert, N.

10.1101/2024.03.04.580093 — microbiology — Posted on 2024-03-05

4416 Salmonella exploits the reactive oxygen species generated by the plant immune system to enhance colonization

Tzpilevich, E.; Aldin, M. S.

10.1101/2024.03.04.583411 — microbiology — Posted on 2024-03-05

4417 Microbial nitrogen guilds in the oceans: from the bathypelagic to the ocean surface

Rivas-Santisteban, J.; Fernandez-Gonzalez, N.; Laso-Perez, R.; Tamames, J.; Pedros-Alio, C.

10.1101/2024.03.05.583471 — microbiology — Posted on 2024-03-05

4418 Step-wise evolution of azole resistance through copy number variation followed by KSR1 loss of heterozygosity in Candida albicans.

Zande, P. V.; Gautier, C.; Kawar, N.; Maufrais, C.; Metzner, K.; Wash, E.; Beach, A. K.; Bracken, R.; Maciel, E. I.; Fernandes, C. M.; Solis, N. V.; Del Poeta, M.; Filler, S. G.; Berman, J.; Ene, I. V.; Selmecki, A.

10.1101/2024.03.05.583528 — microbiology — Posted on 2024-03-05

4419 Pure yeasts selected from fermenting pear juice from the Lower Austrian Mostviertel region and their suitability for pear wine production

Gangl, H.; Tscheik, G.; Tiefenbrunner, W.

10.1101/2024.03.05.583456 — microbiology — Posted on 2024-03-05

4420 Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences

Hawley, D. M.; Perez-Umphrey, A.; Adelman, J. S.; Fleming-Davies, A. E.; Garrett-Larsen, J.; Geary, S. J.; Childs, L. M.; Langwig, K. E.

10.1101/2024.03.05.583455 — microbiology — Posted on 2024-03-05

4421 The latent stage of Toxoplasma gondii is targeted by the immune response and host protective

Shallberg, L. A.; Eberhard, J. N.; Winn, A.; Chandrasekaran, S.; Giuliano, C. J.; Merritt, E. F.; Willis, E.; Christian, D. A.; Aldridge, D. L.; Bunkofske, M.; Jacquet, M.; Dzierszinski, F.; Katifori, E.; Lourido, S.; Koshy, A. A.; Hunter, C. A.

10.1101/2024.03.05.583527 — microbiology — Posted on 2024-03-05

4422 Spectral Characterization of a Blue Light-Emitting Micro-LED Platform and Microbial Chromophores for Therapeutic Applications in Skin Conditions

Serrage, H.; Eling, C. A.; Alves, P. U.; McBain, A. J.; O'Neill, C.; Laurand, N.

10.1101/2024.03.05.582921 — microbiology — Posted on 2024-03-05

4423 A 10-valent composite mRNA vaccine against both influenza and COVID-19

Wang, Y.; Ma, Q.; Li, M.; Mai, Q.; Ma, L.; Zhang, H.; Zhong, H.; Cheng, N.; Feng, P.; Guan, P.; Wu, S.; Zhang, L.; Dai, J.; Zhang, B.; Pan, W.; Yang, Z.

10.1101/2024.03.05.583547 — microbiology — Posted on 2024-03-05

4424 Targeting dermatophyte Cdc42 and Rac GTPase signaling to hinder hyphal elongation and virulence

Ishii, M.; Matsumoto, Y.; Yamada, T.; Uga, H.; Katada, T.; Ohata, S.

10.1101/2024.03.04.583433 — microbiology — Posted on 2024-03-05

4425 Single cell sequencing of pig lungs reveals immune responses underlying influenza infection and oseltamivir therapy

Madrid, D. M. D.; Gu, W.; Warren, W. C.; Driver, J. P.

10.1101/2024.03.05.581049 — immunology — Posted on 2024-03-05

4426 The Role of Inhibition in fMRI Resting-State Negative Correlations

Harita, S.; Momi, D.; Wang, Z.; Bastiaens, S. P.; Griffiths, J. D.

10.1101/2024.03.01.583030 — neuroscience — Posted on 2024-03-05

4427 Cerebellar Purkinje Cells Control Posture in Larval Zebrafish (Danio rerio)

Auer, F.; Nardone, K.; Matsuda, K.; Hibi, M.; Schoppik, D.

10.1101/2023.09.12.557469 — neuroscience — Posted on 2024-03-05

4428 Beyond power limits: the kinetic energy capacity of skeletal muscle

Labonte, D.; Holt, N. C.

10.1101/2024.03.02.583090 — zoology — Posted on 2024-03-05

4429 Isobaric crosslinking mass spectrometry technology for studying conformational and structural changes in proteins and complexes

Ranish, J.; Luo, J.

10.1101/2022.12.02.518925 — systems biology — Posted on 2024-03-05

4430 Learning the Relationship Between Variants, Metabolic Fluxes and Phenotypes

Kim, D.; Han, S.; Nam, S.-H.; Kim, T. Y.

10.1101/2024.03.04.577140 — bioinformatics — Posted on 2024-03-05

4431 Why is the Omicron main protease of SARS-CoV-2 less stable than its wild-type counterpart? A crystallographic, biophysical, and theoretical study of the free enzyme and its complex with inhibitor 13b-K

Ibrahim, M.; Sun, X.; de Oliveira, V. M.; Liu, R.; Clayton, J.; El Kilani, H.; Shen, J.; Hilgenfeld, R.

10.1101/2024.03.04.583178 — biochemistry — Posted on 2024-03-05

4432 Novel Evolution of the Mineralocorticoid Receptor in Humans compared to Chimpanzees, Gorillas and Orangutans

Katsu, Y.; Zhang, J.; Baker, M. E.

10.1101/2023.12.08.570861 — evolutionary biology — Posted on 2024-03-05

4433 Filopodial Mechanotransduction is regulated by Angiotensin-Converting Enzyme 2 (ACE2) and by SARS-CoV-2 spike protein

Jackson, P. K.; He, W.; Wu, C.-T.

10.1101/2024.03.01.581813 — cell biology — Posted on 2024-03-05

4434 Chemotherapy activates inflammasomes to cause inflammation-associated bone loss

Wang, C.; Kaur, K.; Xu, C.; Abu-Amer, Y.; Mbalaviele, G.

10.1101/2023.10.06.561196 — cell biology — Posted on 2024-03-05

4435 Bacteroides vesicles promote functional alterations in gut microbiota composition

Shagaleeva, O. Y.; Kashatnikova, D. A.; Kardonsky, D. A.; Efimov, B. A.; Ivanov, V. A.; Evsiev, S. S.; Zubkov, E. A.; Abramova, O. V.; Zorkina, Y. A.; Morozova, A. Y.; Vorobeva, E. A.; Silantiev, A. S.; Kolesnikova, I. V.; Markelova, M. I.; Olekhnovich, E. I.; Morozov, M. D.; Zoruk, P. Y.; Boldyreva, D. I.; Vanyushkina, A.; Chaplin, A. V.; Grigoryeva, T. V.; Zakharzhevskaya, N. B.

10.1101/2024.03.05.583531 — microbiology — Posted on 2024-03-05

4436 Early-branching cyanobacteria up-regulate superoxide dismutase activity under a simulated early Earth anoxic atmosphere.

Tamanna, S. S.; Boden, J. S.; Kaiser, K. M.; Wannicke, N.; Hoering, J.; Sanchez-Baracaldo, P.; Deponte, M.; Frankenberg-Dinkel, N.; Gehringer, M. M.

10.1101/2024.03.05.583491 — microbiology — Posted on 2024-03-05

4437 Antibacterial T6SS1 cluster identification and bioinformatics characterization of their putative effectors in Shiga toxin-producing Escherichia coli

Riviere, N. A.; Casabonne, M. C.; Smith, L. Y.; Marques Da Silva, W.; Cataldi, A. A.; Larzabal, M.

10.1101/2024.03.05.583533 — microbiology — Posted on 2024-03-05

4438 Salmonella Typhimurium infection inhibits macrophage IFNbeta signaling in a TLR4-dependent manner

Shuster, M.; Lyu, Z.; Augenstreich, J.; Mathur, S.; Ganesh, A.; Ling, J.; Briken, V.

10.1101/2024.03.05.583530 — microbiology — Posted on 2024-03-05

4439 Seasonal exometabolites are regulated by essential microbial metabolisms in the oligotrophic ocean

McParland, E. L.; Wittmers, F.; Bolanos, L. M.; Carlson, C. A.; Giovannoni, S. J.; Michelsen, M.; Parsons, R.; Kido Soule, M. C.; Swarr, G. J.; Temperton, B.; Vergin, K.; Worden, A. Z.; Longnecker, K.; Kujawinski, E. B.

10.1101/2024.03.05.583599 — microbiology — Posted on 2024-03-05

4440 Biological modifications of the immune response to COVID-19 vaccine in patients treated with anti-CD20 agents and immune-checkpoint inhibitors

Ravera, F.; Dameri, M.; Lombardo, I.; Stabile, M.; Fallani, N.; Scarsi, C.; Cigolini, B.; Gentilcore, G.; Domnich, A.; Zullo, L.; Cella, E.; Francia, G.; Montanari, E.; Orsi, A.; Bellodi, A.; Ferrando, F.; Rinchai, D.; Ballerini, F.; Bruzzone, B.; Chaussabel, D.; Grivel, J.-C.; Genova, C.; Lemoli, R.; Bedognetti, D.; Ballestrero, A.; Ferrando, L.; Zoppoli, G.

10.1101/2024.03.05.583494 — immunology — Posted on 2024-03-05

4441 SARS-CoV-2 modulates NK cell responses via induction of HLA-E and triggers expansion of adaptive NK cells during acute infection

Hasan, M. Z.; Claus, M.; Kruger, N.; Reusing, S.; Gall, E.; Bade-Doding, C.; Braun, A.; Watzl, C.; Uhrberg, M.; Walter, L.

10.1101/2024.03.04.583260 — immunology — Posted on 2024-03-05

4442 Prefrontal neuronal dynamics in the absence of task execution

Pu, S.; Dang, W.; Qi, X.; Constantinidis, C.

10.1101/2022.09.16.508324 — neuroscience — Posted on 2024-03-05

4443 A Panoramic View of Cell Population Dynamics in Mammalian Aging

Zhang, Z.; Schaefer, C.; Jiang, W.; Lu, Z.; Lee, J.; Sziraki, A.; Abdulraouf, A.; Wick, B.; Haeussler, M.; Li, Z.; Molla, G.; Satija, R.; Zhou, W.; Cao, J.

10.1101/2024.03.01.583001 — genomics — Posted on 2024-03-05

4444 Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies

Nazeen, S.; Wang, X.; Zielinski, D.; Lam, I.; Xu, P.; Ethier, E.; Strom, R.; Zanella, C. A.; Nithianandam, V.; Ritter, D.; Henderson, A.; Saurat, N.; Nutter-Upham, A.; Benyamini, H.; Copty, J.; Ravishankar, S.; Morrow, A.; Mitchel, J.; Neavin, D.; Gupta, R.; Farbehi, N.; Grundman, J.; Myers, R. H.; Scherzer, C. R.; Trojanowski, J. Q.; Van Deerlin, V. M.; Cooper, A. A.; Lee, E. B.; Erlich, Y.; Lindquist, S.; Peng, J.; Geschwind, D. H.; Powell, J.; Studer, L.; Feany, M. B.; Sunyaev, S. R.; Khurana, V.

10.1101/2024.03.03.583145 — genomics — Posted on 2024-03-05

4445 CRIPTO promotes extracellular vesicle uptake and activation of fibroblast exposed to triple negative breast cancer cells

Freeman, D. W.; Gates, B. L.; Spendlove, M. D.; Gulbahce, H. E.; Spike, B. T.

10.1101/2024.03.01.583059 — cancer biology — Posted on 2024-03-05

4446 Non-Invasive Perfusion MR Imaging of the Human Brain via Breath-Holding

Schulman, J. B.; Kashyap, S.; Kim, S.-G.; Uludag, K.

10.1101/2023.08.24.554712 — biophysics — Posted on 2024-03-05

4447 Nanopore sequencing with unique molecular identifiers enables accurate mutation analysis and haplotyping in the complex Lipoprotein(a) KIV-2 VNTR

Amstler, S.; Streiter, G.; Pfurtscheller, C.; Forer, L.; Di Maio, S.; Weissensteiner, H.; Paulweber, B.; Schoenherr, S.; Kronenberg, F.; Coassin, S.

10.1101/2024.03.01.582741 — genomics — Posted on 2024-03-05

4448 Activity of spinal RORβ neurons is related to functional improvements following combination treatment after complete SCI

Stachowski, N. J.; Wheel, J. H.; Atoche, S.; Yao, L.; Garcia-Ramirez, D. L.; Giszter, S. F.; Dougherty, K. J.

10.1101/2024.03.01.583033 — neuroscience — Posted on 2024-03-05

4449 Coupling of saccade plans to endogenous attention during urgent choices

Goldstein, A. T.; Stanford, T. R.; Salinas, E.

10.1101/2024.03.01.583058 — neuroscience — Posted on 2024-03-05

4450 Molecular control of temporal integration matches decision-making to motivational state

Gautham, A. K.; Miner, L. E.; Franco, M. N.; Thornquist, S. C.; Crickmore, M. A.

10.1101/2024.03.01.582988 — neuroscience — Posted on 2024-03-05

4451 Disentangling plant response to biotic and abiotic stress using HIVE, a novel tool to perform unpaired multi-omics integration

Calia, G.; Zotta Mota, A. P.; Seynabou, M.; Nguyen, H. T.; Ghat, A.; Schuler, H.; Gwizdek, C.; Brasileiro, A.; Guimares, P.; BOTTINI, S.

10.1101/2024.03.04.583290 — plant biology — Posted on 2024-03-05

4452 FACS-Sortable Picoreactors for Ultra High-throughput Screening of Catalysts in Biphasic Environments

Thompson, S.; Zhang, Y.; Yang, Z.; Nichols, L. A.; Fordyce, P. M.

10.1101/2024.03.01.583031 — bioengineering — Posted on 2024-03-05

4453 Fibroblasts as an in vitro model of circadian genetic and genomic studies

Francia, M.; Bot, M.; Boltz, T.; De La Hoz, J. F.; Boks, M.; Kahn, R.; Ophoff, R.

10.1101/2023.05.19.541494 — genomics — Posted on 2024-03-05

4454 Chromosome-level genome assembly of the disco clam, Ctenoides ales, a first for the bivalve order Limida

McElroy, K. E.; Masonbrink, R. E.; Chudalayandi, S.; Severin, A. J.; Serb, J. M.

10.1101/2024.03.01.583045 — evolutionary biology — Posted on 2024-03-05

4455 Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control

Vietri Rudan, M.; Sipilä, K. H.; Philippeos, C.; Ganier, C.; Negri, V. A.; Watt, F. M.

10.1101/2023.12.19.572393 — cell biology — Posted on 2024-03-05

4456 Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons

Santiago, A. N.; Castello-Saval, J.; Nguyen, P.; Chung, H.; Luna, V. M.; Hen, R.; Chang, W.-l.

10.1101/2024.03.01.583011 — neuroscience — Posted on 2024-03-05

4457 Spatiotemporally-specific cortical-subthalamic coupling differentiates aspects of speech performance

Vissani, M.; Bush, A.; Lipski, W. J.; Fischer, P.; Neudorfer, C.; Holt, L. L.; Fiez, J. A.; Turner, R. S.; Richardson, R. M.

10.1101/2023.10.18.562969 — neuroscience — Posted on 2024-03-05

4458 Artificial neural network for brain-machine interface consistently produces more naturalistic finger movements than linear methods

Temmar, H.; Willsey, M. S.; Costello, J. T.; Mender, M. J.; Cubillos, L. H.; Lam, J. L.; Wallace, D. M.; Kelberman, M. M.; Patil, P. G.; Chestek, C. A.

10.1101/2024.03.01.583000 — neuroscience — Posted on 2024-03-05

4459 Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning.

Venditto, S. J. C.; Miller, K. J.; Brody, C. D.; Daw, N. D.

10.1101/2024.02.28.582617 — neuroscience — Posted on 2024-03-05

4460 Developmental hematopoietic stem cell variation explains clonal hematopoiesis later in life

Kreger, J.; Mooney, J. A.; Shibata, D.; MacLean, A. L.

10.1101/2024.03.02.583106 — systems biology — Posted on 2024-03-05

4461 Stomatal CO2-responses at sub- and above-ambient CO2 levels employ different pathways in Arabidopsis

Koolmeister, K.; Merilo, E.; Horak, H.; Kollist, H.

10.1101/2021.05.13.443984 — plant biology — Posted on 2024-03-05

4462 Synthesis and Biological Assessment of Chalcone and Pyrazoline Derivatives as novel inhibitor for ELF3-MED23 Interaction

Hwang, S.-Y.; Jeon, K.-H.; Lee, H.-J.; Moon, I.; Jung, S.; Kim, S.-A.; Jo, H.; Park, S.; Ahn, M.; Kwak, S.-Y.; Na, Y.; Kwon, Y.

10.1101/2024.03.01.583029 — pharmacology and toxicology — Posted on 2024-03-05

4463 Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior

Zeledon, E. V.; Baxt, L. A.; Khan, T. A.; Michino, M.; Miller, M.; Huggins, D. J.; Jiang, C. S.; Vosshall, L. B.; Duvall, L. B.

10.1101/2024.02.28.582529 — pharmacology and toxicology — Posted on 2024-03-05

4464 Development of an MRI-compatible robotic perturbation system for studying the task-dependent contribution of the brainstem to long-latency responses

Nikonowicz, R. C.; Sergi, F.

10.1101/2024.03.01.583025 — bioengineering — Posted on 2024-03-05

4465 Bacteria in honeybee crops are decoupled from those in floral nectar and bee mouths

Warren, M. L.; Tsuji, K.; Decker, L. E.; Kishi, M.; Yang, J.; Howe, A. C.; Fukami, T.

10.1101/2024.03.01.583024 — ecology — Posted on 2024-03-05

4466 FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans

Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.

10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-05

4467 A comprehensive investigation of intracortical and corticothalamic models of alpha rhythms

Bastiaens, S. P.; Momi, D.; Griffiths, J. D.

10.1101/2024.03.01.583035 — neuroscience — Posted on 2024-03-05

4468 Calcium-dependent regulation of neuronal excitability is rescued in Fragile X Syndrome by a tat-conjugated N-terminal fragment of FMRP

Zhan, X.; Asmara, H.; Pfaffinger, P. J.; Turner, R. W.

10.1101/2024.03.01.583006 — neuroscience — Posted on 2024-03-05

4469 The spiking output of the mouse olfactory bulb encodes large-scale temporal features of natural odor environments

Lewis, S. M.; Suarez, L. M.; Rigolli, N.; Steinmetz, N. A.; Gire, D. H.

10.1101/2024.03.01.582978 — neuroscience — Posted on 2024-03-05

4470 Inflammation promotes aging-associated oncogenesis in the lung.

Pham-Danis, C.; Chia, S. B.; Scarborough, H. A.; Danis, E.; Nemkov, T.; Kleczko, E. K.; Navarro, A.; Goodspeed, A.; Bonney, E. A.; Dinarello, C. A.; Marchetti, C.; Nemenoff, R. A.; Hansen, K. A.; DeGregori, J.

10.1101/2024.03.01.583044 — cancer biology — Posted on 2024-03-05

4471 Age-related behavioral resilience in smartphone touchscreen interaction dynamics

Ceolini, E.; Ridderinkhof, K. R.; Ghosh, A.

10.1101/2024.03.01.583034 — animal behavior and cognition — Posted on 2024-03-05

4472 Expanding the Drosophila toolkit for dual control of gene expression

Zirin, J.; Jusiak, B.; Lopes, R.; Ewen-Campen, B.; Bosch, J. A.; Risbeck, A.; Forman, C.; Villalta, C.; Hu, Y.; Perrimon, N.

10.1101/2023.08.15.553399 — genetics — Posted on 2024-03-05

4473 Ubiquitous nonidentifiability of state-dependent diversification models (SSEs) is not problematic for phylogenetics

Tarasov, S.; Uyeda, J.

10.1101/2022.07.04.498736 — evolutionary biology — Posted on 2024-03-05

4474 A high-throughput platform for single-molecule tracking identifies drug interaction and cellular mechanisms

McSwiggen, D. T.; Liu, H.; Tan, R.; Agramunt Puig, S.; Akella, L. B.; Berman, R.; Bretan, M.; Chen, H.; Darzacq, X.; Ford, K.; Godbey, R.; Gonzalez, E.; Hanuka, A.; Heckert, A.; Ho, J. J.; Johnson, S. L.; Kelso, R.; Klammer, A.; Krishnamurthy, R.; Li, J.; Lin, K.; Margolin, B.; McNamara, P.; Meyer, L.; Pierce, S. E.; Sule, A.; Stashko, C.; Tang, Y.; Anderson, D. J.; Beck, H.

10.1101/2023.01.05.522916 — cell biology — Posted on 2024-03-05

4475 Metabolic Vulnerabilities of Temozolomide-Resistant Glioblastoma Cells: Implications for Targeted Therapies and Overcoming Chemoresistance

Amereh, M.; Seyfoori, A.; Shojaei, S.; Lane, S.; Zhao, T.; Shokrollahi, M.; Lum, J.; Walter, P.; Akbari, M.

10.1101/2024.03.01.582997 — cancer biology — Posted on 2024-03-05

4476 Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure

Shim, A. R.; Frederick, J.; Pujadas, E. M.; Kuo, T.; Ye, I. C.; Pritchard, J. A.; Dunton, C. L.; Carrillo Gonzalez, P.; Acosta, N.; Jain, S.; Anthony, N. M.; Almassalha, L. M.; Szleifer, I.; Backman, V.

10.1101/2024.03.01.582995 — biophysics — Posted on 2024-03-05

4477 Correlating fluorescence microscopy, optical and magnetic tweezers to study single chiral biopolymers such as DNA

Shepherd, J.; Guilbaud, S.; Zhou, Z.; Howard, J.; Burman, M.; Schaefer, C.; Kerrigan, A.; Steele-King, C.; Noy, A.; Leake, M. C.

10.1101/2024.01.18.576226 — biophysics — Posted on 2024-03-05

4478 Gut Microbiome-Driven Metabolites Influence Skin Pigmentation in TYRP1 Mutant Oujiang Color Common Carp

Mandal, R. N.; Ke, J.; Kanika, N. H.; Hou, X.; Zhang, Z.; Zhang, P.; Chen, H.; Zeng, C.; Chen, X.; Wang, J.; Wang, C.

10.1101/2024.03.01.583018 — genetics — Posted on 2024-03-05

4479 Temporal dynamics of human color processing measured using a continuous tracking task

Barnett, M. A.; Chin, B. M.; Aguirre, G. K.; Burge, J.; Brainard, D. H.

10.1101/2024.03.01.582975 — neuroscience — Posted on 2024-03-05

4480 Electrocorticographic and Astrocytic Signatures of Stearoyl-CoA Desaturase Inhibition in the Triple Transgenic Mouse Model of Alzheimer's Disease

Hector, A.; da Costa Caiado, M. J.; Leduc, T.; Delignat-Lavaud, B.; Dufort-Gervais, J.; Bourguignon, C.; Lina, J.-M.; Fernandes, K.; Brouillette, J.; Mongrain, V.

10.1101/2024.03.01.582986 — neuroscience — Posted on 2024-03-05

4481 Human brain aging heterogeneity observed from multi-region omics data reveals a subtype closely related to Alzheimer's disease

Peng, S.; Wang, E.; Wang, M.; Wang, X.; Yu, K.; Fu, Y.; Poudel, S.; Ho, L.; Narayan, S.; Huffman, D.; Gaiteri, C.; Bennett, D. A.; Ehrlich, M. E.; Haroutunian, V.; Peng, J.; Zhang, B.; Tu, Z.

10.1101/2024.03.01.582970 — neuroscience — Posted on 2024-03-05

4482 The lipidome of posttraumatic stress disorder

Bhargava, A.; Knapp, J. D.; Fiehn, O.; Neylan, T. C.; Inslicht, S. S.

10.1101/2024.02.23.581833 — systems biology — Posted on 2024-03-05

4483 Decentralizing genetic testing for biodiversity monitoring and biosurveillance with the Nucleic Acid Barcode Identification Tool (NABIT) and Molecular Development Kit (MDK).

Holmes, H.; Winters, M.; Fang, C.; Fotouhi, G.; Mercader, J.; Fox, D. A.; Bunje, P. M.; Dehgan, A.

10.1101/2024.03.01.582993 — bioengineering — Posted on 2024-03-05

4484 Do seabirds dream of artificial lights? Understanding light preferences of Procellariiformes

Atchoi, E.; Mitkus, M.; Machado, B.; Medeiros, V.; Garcia, S.; Juliano, M.; Bried, J.; Rodriguez, A.

10.1101/2024.03.01.582998 — animal behavior and cognition — Posted on 2024-03-05

4485 The Genetic Basis of Incipient Sexual Isolation in Drosophila melanogaster

Yamamoto, A.; Huang, W.; Carbone, M. A.; Anholt, R. R. H.; Mackay, T.

10.1101/2024.03.01.582979 — genetics — Posted on 2024-03-05

4486 RNA polymerase III is involved in regulating Plasmodium falciparum virulence

Diffendall, G. M.; Claes, A.; Barcons-Simon, A.; Nyarko, P.; Dingli, F.; Santos, M.; Loew, D.; Claessens, A.; Scherf, A.

10.1101/2023.07.18.549525 — microbiology — Posted on 2024-03-05

4487 Spiking attractor model of motor cortex explains modulation of neural and behavioral variability by prior target information

Rostami, V.; Rost, T.; Schmitt, F. J.; van Albada, S. J.; Riehle, A.; P. Nawrot, M.

10.1101/2020.02.27.968339 — neuroscience — Posted on 2024-03-05

4488 The Molecular Landscape of Cellular Metal Ion Biology

Aulakh, S. K.; Lemke, O.; Szyrwiel, L.; Kamrad, S.; Chen, Y.; Hartl, J.; Muelleder, M.; Nielsen, J.; Ralser, M.

10.1101/2024.02.29.582718 — systems biology — Posted on 2024-03-05

4489 Identification of RACK1A as a component of the auxin-ethylene crosstalk regulating apical hook development in Arabidopsis thaliana

Ma, Q.; Liu, S.; Raggi, S.; Doyle, S. M.; Parizkova, B.; Barange, D. K.; Wilkinson, E. G.; Crespo Garcia, I.; Bygdell, J.; Wingsle, G.; Boer, D. R.; Strader, L. C.; Almqvist, F.; Novak, O.; Robert, S.

10.1101/2024.03.04.582885 — plant biology — Posted on 2024-03-05

4490 Regulation of Arabidopsis polyamine acetylation by NATA1 and NATA2

Hameed, U. F. S.; Luo, Y.-R.; Yan, J.; Guzman-Vega, F. J.; Aleksenko, E.; Briozzo, P.; MORERA, S.; Jander, G.; Arold, S. T.

10.1101/2024.03.04.583282 — plant biology — Posted on 2024-03-05

4491 Small, but mitey: Investigating the molecular genetic basis for mite domatia development and intraspecific variation in Vitis riparia using transcriptomics

Ritter, E. J.; Graham, C. D. K.; Niederhuth, C.; Weber, M. G.

10.1101/2024.03.04.583436 — plant biology — Posted on 2024-03-05

4492 Identification of new resistance QTL regions in loquat cultivar Champagne against Pseudomonas syringae pv. eriobotryae group C

Koga, S.; Kawaguchi, R.; Tanaka, T.; Moriya, S.; Hiehata, N.; Kabashima, K.; Nagano, A. J.; Nagano, Y.; Fukuda, S.

10.1101/2024.03.04.583427 — plant biology — Posted on 2024-03-05

4493 Biological Control of Green Mold in Simulated Post-harvest Chain of Citrus Fruit: Efficacy of Candida oleophila Strain O and Molecular Insight into Elicitation of Host Immune System

Rovetto, E. I.; La Spada, F.; El Boumlasy, S.; Conti Taguali, S.; Riolo, M.; Pane, A.; Cacciola, S. O.

10.1101/2024.03.05.583495 — plant biology — Posted on 2024-03-05

4494 Viral delivery of recombinases to activate heritable genetic switches in plants

Chamness, J. C.; Cody, J. P.; Cruz, A. J.; Voytas, D.

10.1101/2024.03.03.583219 — plant biology — Posted on 2024-03-05

4495 Spray-induced gene silencing (SIGS) as a tool for the management of Pine Pitch Canker forest disease

Bocos Asenjo, I. T.; Amin, H.; Mosquera, S.; Diez Hermano, S.; Ginesy, M.; Diez, J. J.; Nino Sanchez, J.

10.1101/2024.03.05.583474 — plant biology — Posted on 2024-03-05

4496 Overexpression of PpGL2 from Prunus persica enhanced soybean drought tolerance

Li, W.; Li, D.; Zhao, L.; Li, H.

10.1101/2024.03.03.583192 — plant biology — Posted on 2024-03-05

4497 H1 restricts euchromatin-associated methylation pathways from heterochromatic encroachment

Harris, C. J.; Zhong, Z.; Ichino, L.; Feng, S.; Jacobsen, S. E.

10.1101/2023.05.10.539968 — plant biology — Posted on 2024-03-05

4498 Time dependent changes in feeding behavior and energy balance associated with weight gain in mice fed obesogenic diets

Fathi, P. A.; Bales, M. B.; Ayala, J. E.

10.1101/2024.01.10.575043 — physiology — Posted on 2024-03-05

4499 Mining drug-target interactions from biomedical literature using chemical and gene descriptions-based ensemble transformer model.

Aldahdooh, J.; Tanoli, Z.; Tang, J.

10.1101/2023.07.24.550359 — bioinformatics — Posted on 2024-03-05

4500 CAMPER: curated annotations for profiling microbial polyphenol metabolic potential

McGivern, B. B.; Woyda, R.; Flynn, R. M.; Wrighton, K. C.

10.1101/2023.09.24.559193 — bioinformatics — Posted on 2024-03-05

4501 Unveiling the Intricate Sinking behavior of Large Diatoms: Insights from Time-Frequency Analysis of Palmerina hardmaniana Sinking under Silicate-Depleted Conditions

Ping, Z.; Lu, J.; Li, L.; Zhuang, J.; Lai, J.; Shi, T.; Li, J.

10.1101/2024.03.03.582478 — plant biology — Posted on 2024-03-05

4502 Technique for rapidly forming networks of microvessel-like structures

Hewes, S.; Ahmad, F.; Connell, J.; Grande-Allen, K. J.

10.1101/2023.06.22.546165 — bioengineering — Posted on 2024-03-05

4503 Variations of floral temperature in changing weather conditions

Harrap, M. J. M.; de Vere, N.; Hempel de Ibarra, N.; Whitney, H. M.; Rands, S. A.

10.1101/2024.03.04.583410 — plant biology — Posted on 2024-03-05

4504 Iterative In Silico Screening for Optimizing Stable Conformation of Anti-SARS-CoV-2 Nanobodies

Shang, W.; Hu, X.; Lin, X.; Li, S.; Xiong, S.; Huang, B.; Wang, X.

10.1101/2023.08.09.552633 — bioinformatics — Posted on 2024-03-05

4505 Translational control of MPS1 links protein synthesis with the initiation of cell division and spindle pole body duplication in Saccharomyces cerevisiae

Blank, H. M.; Alonso, A.; Fabritius, A. S.; Winey, M.; Polymenis, M.

10.1101/2020.12.29.424704 — cell biology — Posted on 2024-03-05

4506 Transposition of HOPPLA in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in Brachypodium distachyon

Thieme, M.; Minadakis, N.; Himber, C.; Keller, B.; Xu, W.; rutowicz, K.; Matteoli, C.; Boehrer, M.; Rymen, B.; Laudencia-Chingcuanco, D.; Vogel, J. P.; Sibout, R.; Stritt, C.; Blevins, T.; Roulin, A. C.

10.1101/2023.09.25.559196 — genomics — Posted on 2024-03-05

4507 Interplay between fecundity, sexual and growth selection on the spring phenology of European beech (Fagus sylvatica L.).

Oddou-Muratorio, S.; Bontemps, A.; Gauzere, J.; Klein, E. K.

10.1101/2023.04.27.538521 — evolutionary biology — Posted on 2024-03-05

4508 Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells

Donnelly, H.; Ross, E.; Xiao, Y.; Hermantara, R.; Taqi, A. F. J. M. A.; Doherty-Boyd, W. S.; Cassels, J.; Tsimbouri, P. M.; Dunn, K. M.; Hay, J.; Cheng, Z. A.; Jain, N.; West, C. C.; Wheadon, H.; Michie, A. M.; Peault, B.; West, A. G.; Salmeron-Sanchez, M.; Dalby, M. J.

10.1101/2022.07.28.501818 — bioengineering — Posted on 2024-03-05

4509 Lords of the flies: Dipteran migrants are diverse, abundant and ecologically important

Hawkes, W. L.; Menz, M.; Wotton, K.

10.1101/2024.03.04.583324 — ecology — Posted on 2024-03-05

4510 Metabolic adaptation pilots the differentiation of human hematopoietic cells

Racine, L.; Parmentier, R.; Niphadkar, S.; Laxman, S.; Martignoles, J.-A.; Delhommeau, F.; Paldi, A.

10.1101/2023.09.17.558120 — cell biology — Posted on 2024-03-05

4511 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus

Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.

10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-05

4512 Evolution from mixed to fixed handedness in mirror-image flowers: insights from adaptive dynamics

Saltini, M.; Barrett, S. C. H.; Deinum, E.

10.1101/2023.07.08.548200 — evolutionary biology — Posted on 2024-03-05

4513 Learning the Relationship Between Variants, Metabolic Fluxes and Phenotypes

Kim, D.; Han, S.; Nam, S.-H.; Kim, T. Y.

10.1101/2024.03.04.577140 — bioinformatics — Posted on 2024-03-05

4514 Gretl - Variation GRaph Evaluation TooLkit

Vorbrugg, S.; Bezrukov, I.; Bao, Z.; Weigel, D.

10.1101/2024.03.04.580974 — bioinformatics — Posted on 2024-03-05

4515 Maternal behavior in Sumatran orangutans (Pongo abelii) is modulated by mother-offspring characteristics and socioecological factors

T, R.; Mundry, R.; Utami Atmoko, S. S.; Buerkner, P.-C.; van Noordwijk, M. A.; Schuppli, C.

10.1101/2024.03.02.582963 — animal behavior and cognition — Posted on 2024-03-05

4516 Increased Enhancer-Promoter Interactions during Developmental Enhancer Activation in Mammals

Chen, Z.; Snetkova, V.; Bower, G.; Jacinto, S.; Clock, B.; Dizehchi, A.; Barozzi, I.; Mannion, B. J.; Alcaina-Caro, A.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Kvon, E. Z.

10.1101/2022.11.18.516017 — genomics — Posted on 2024-03-04

4517 Single-cell multiplex chromatin and RNA interactions in aging human brain

Wen, X.; Luo, Z.; Zhao, W.; Calandrelli, R.; Nguyen, T.; Wan, X.; Richard, J. L. C.; Zhong, S.

10.1101/2023.06.28.546457 — genomics — Posted on 2024-03-04

4518 Re-annotation of SARS-CoV-2 proteins using an HHpred-based approach opens new opportunities for a better understanding of this virus

Brezellec, P.

10.1101/2023.06.06.543855 — genomics — Posted on 2024-03-05

4519 RegionScan: A comprehensive R package for region-level genome-wide association testing with integration and visualization of multiple-variant and single-variant hypothesis testing

Brossard, M.; Roshandel, D.; Luo, K.; Yavartanoo, F.; Paterson, A. D.; Yoo, Y. J.; Bull, S. B.

10.1101/2024.03.04.582374 — genetics — Posted on 2024-03-05

4520 Meiotic DSB repair DNA synthesis tracts in Arabidopsis thaliana

Hernandez Sanchez-Rebato, M.; Schubert, V.; White, C. I.

10.1101/2024.02.25.582015 — genetics — Posted on 2024-03-05

4521 Immigration delays but does not prevent adaptation following environmental change: experimental evidence

Durkee, L. F.; Olazcuaga, L.; Melbourne, B. A.; Hufbauer, R. A.

10.1101/2023.08.31.555763 — evolutionary biology — Posted on 2024-03-04

4522 A synthesis on alien mammals threatened in their native range

Tedeschi, L.; Lenzner, B.; Schertler, A.; Biancolini, D.; Rondinini, C.; Essl, F.

10.1101/2024.03.04.582492 — ecology — Posted on 2024-03-05

4523 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'

Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.

10.1101/2023.11.08.566206 — ecology — Posted on 2024-03-05

4524 Visualization of Bacillus subtilis Spore Structure and Germination using Quick-Freeze Deep-Etch Electron Microscopy

Jalil, K.; Tahara, Y. O.; Miyata, M.

10.1101/2024.03.04.579732 — microbiology — Posted on 2024-03-05

4525 Generative Adversarial Implicit Successor Representation

Choi, W.-H.; Ha, S.; Choi, H.

10.1101/2024.03.03.581078 — neuroscience — Posted on 2024-03-05

4526 The inflammatory micro-environment induced by targeted CNS radiotherapy is underpinned by disruption of DNA methylation

Millner, T. O.; Panday, P.; Xiao, Y.; Boot, J. R.; Nicholson, J.; Arpe, Z.; Stevens, P.; Rahman, N.; Zhang, X.; Mein, C.; Kitchen, N.; McEvoy, A. W.; McKintosh, E.; McKenna, G.; Paraskevopoulos, D.; Lewis, R.; Badodi, S.; Marino, S.

10.1101/2024.03.04.581366 — neuroscience — Posted on 2024-03-05

4527 Evaluation of efficacy of formic acid and thermal remediation for management of Tropilaelaps and Varroa mites in central Thailand

Sankovitz, M.; Steinhauer, N.; Yemor, T.; Cook, S. C.; Evans, J. D.; Ramsey, S. D.

10.1101/2024.03.04.582002 — zoology — Posted on 2024-03-05

4528 Chronic infection alters pathogen virulence, microbiome composition, and fly physiology across generations.

Maya-Maldonado, K.; Broderick, N. A.

10.1101/2024.03.04.583275 — physiology — Posted on 2024-03-05

4529 Synergistic and antagonistic drug interactions are prevalent but not conserved across acute myeloid leukemia cell lines

Kalkan, F. N.; Yildiz, M. S.; Wood, N. E.; Farid, M.; McCoy, M.; Zhang, C.; Lin, M.; Posner, B.; Chung, S. S.; Toprak, E.

10.1101/2024.02.23.581821 — cancer biology — Posted on 2024-03-05

4530 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis

Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.

10.1101/2024.02.28.582624 — biophysics — Posted on 2024-03-05

4531 Cell-penetrating peptides stimulate protein transport on the Twin-arginine translocation pathway: evidence for a membrane thinning and toroidal pore mechanism

McNeilage, R.; Ganesan, I.; Keilman, J.; Theg, S. M.

10.1101/2023.07.08.548235 — biochemistry — Posted on 2024-03-05

4532 Identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes, supported by short- and long-read transcriptome data

Jutersek, M.; Gerasymenko, I. M.; Petek, M.; Haumann, E.; Vacas Gonzalez, S.; Kallam, K.; Gianoglio, S.; Navarro-Llopis, V.; Navarro Fuertes, I.; Patron, N.; Orzaez, D.; Gruden, K.; Warzecha, H.; Baebler, S.

10.1101/2023.06.09.544309 — biochemistry — Posted on 2024-03-05

4533 FARMS: Framework for Animal and Robot Modeling and Simulation

Arreguit, J.; Tata Ramalingasetty, S.; Ijspeert, A. J.

10.1101/2023.09.25.559130 — animal behavior and cognition — Posted on 2024-03-05

4534 Physiological traits and their relationships vary along an elevational gradient within and among Fijian bee species

da Silva, C. R. B.; Beaman, J. E.; Tuiwawa, M.; Stevens, M. I.; Schwarz, M. P.; Gloag, R.; Kellermann, V.; Alton, L. A.

10.1101/2022.07.27.501487 — evolutionary biology — Posted on 2024-03-04

4535 Photoreceptor calyceal processes accompany the developing outer segment, adopting a stable length despite a dynamic core

Sharkova, M.; Aparicio, G.; Mouzaaber, C.; Zolessi, F. R.; Hocking, J. C.

10.1101/2023.10.04.560921 — cell biology — Posted on 2024-03-04

4536 A Parasite Odyssey: An RNA virus concealed in Toxoplasma gondii

Gupta, P.; Hiller, A.; Chowdhury, J.; Lim, D.; Lim, D. Y.; Saeij, J. P.; Babaian, A.; Rodriguez, F.; Pereira, L.; Morales, A.

10.1101/2023.09.17.558162 — microbiology — Posted on 2024-03-04

4537 Exploring neural tracking of acoustic and linguistic speech representations in individuals with post-stroke aphasia

Kries, J.; De Clercq, P.; Gillis, M.; Vanthornhout, J.; Lemmens, R.; Francart, T.; Vandermosten, M.

10.1101/2023.03.01.530707 — neuroscience — Posted on 2024-03-04

4538 Spatial arrangement of the whiskers of harbor seals (Phoca vitulina) compared to whisker arrangements of mice (Mus musculus) and rats (Rattus norvegicus)

Graff, M. M.; Belli, H. M.; Wieskotten, S.; Bresee, C. S.; Krüger, Y.; Janssen, T. L.; Dehnhardt, G.; Hartmann, M. J. Z.

10.1101/2024.01.15.575743 — neuroscience — Posted on 2024-03-04

4539 Mammalian Cell Models of the Distal Convoluted Tubule: A Systematic Review of Cell Lines, Culture Condition and Gene Expression

Zhong, C.; Sun, Z.; Grillo, A.; Walsh, S. B.; Siew, K.

10.1101/2024.02.23.581724 — physiology — Posted on 2024-03-04

4540 Competitive Amplification Networks enable molecular pattern recognition with PCR

Goertz, J. P.; Sedgwick, R.; Smith, F.; Kaforou, M. P.; Wright, V. J.; Herberg, J. A.; Kote-Jarai, Z.; Eeles, R.; Levin, M.; Misener, R.; van der Wilk, M.; Stevens, M. M.

10.1101/2023.06.29.546934 — bioengineering — Posted on 2024-03-04

4541 Structure-guided mutagenesis of OSCAs reveals differential activation to mechanical stimuli

Jojoa-Cruz, S.; Dubin, A. E.; Lee, W.-H.; Ward, A. B.

10.1101/2023.10.03.560740 — biochemistry — Posted on 2024-03-04

4542 RNA G-quadruplexes and calcium ions synergistically induce Tau phase transition in vitro

Yabuki, Y.; Matsuo, K.; Komiya, G.; Kudo, K.; Hori, K.; Ikenoshita, S.; Kawata, Y.; Mizobata, T.; Shioda, N.

10.1101/2024.03.01.582861 — biochemistry — Posted on 2024-03-04

4543 Coevolution of longevity and female germline maintenance

Baur, J.; Koppik, M.; Savkovic, U.; Dordevic, M.; Stojkovic, B.; Berger, D.

10.1101/2023.12.03.569746 — evolutionary biology — Posted on 2024-03-04

4544 Endocardial HDAC3 is required for myocardial trabeculation

Jang, J.; Bentsen, M.; Kim, Y. J.; Kim, E.; Garg, V.; Cai, C.-L.; Looso, M.; Li, D.

10.1101/2023.04.12.536668 — developmental biology — Posted on 2024-03-04

4545 A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects

Kathiriya, I. S.; Dominguez, M. H.; Rao, K. S.; Muncie-Vasic, J. M.; Devine, W. P.; Hu, K. M.; Hota, S. K.; Garay, B. I.; Quintero, D.; Goyal, P.; Matthews, M. N.; Thomas, R.; Sukonnik, T.; Miguel-Perez, D.; Winchester, S.; Brower, E. F.; Forjaz, A.; Wu, P.-H.; Wirtz, D.; Kiemen, A. L.; Bruneau, B. G.

10.1101/2024.02.05.578995 — developmental biology — Posted on 2024-03-04

4546 Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis

Dill-McFarland, K. A.; Simmons, J. D.; Peterson, G. J.; Nguyen, F. K.; Campo, M.; Benchek, P.; Stein, C.; Vaisar, T.; Mayanja-Kizza, H.; Boom, W. H.; Hawn, T.

10.1101/2024.02.27.582348 — immunology — Posted on 2024-03-04

4547 Downregulation of Let-7 miRNA promotes Tc17 differentiation and emphysema via de-repression of RORγt

Erice, P. A.; Huang, X.; Seasock, M. J.; Robertson, M. J.; Tung, H.-Y.; Perez-Negron, M. A.; Lotlikar, S. L.; Corry, D. B.; Kheradmand, F.; Rodriguez, A.

10.1101/2023.10.12.562059 — immunology — Posted on 2024-03-04

4548 Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation

Witt, L.; Greenfield, K.; Knoop, K.

10.1101/2023.10.02.560561 — immunology — Posted on 2024-03-04

4549 On prefrontal working memory and hippocampal episodic memory: Unifying memories stored in weights and activity slots

Whittington, J. C. R.; Dorrell, W.; Behrens, T. E. J.; Ganguli, S.; El-Gaby, M.

10.1101/2023.11.05.565662 — neuroscience — Posted on 2024-03-04

4550 Computational and neural mechanisms underlying the influence of action affordances on value learning

Yi, S.; O'Doherty, J. P.

10.1101/2023.07.21.550102 — neuroscience — Posted on 2024-03-04

4551 Cell class-specific electric field entrainment of neural activity

Lee, S. Y.; Kozalakis, K.; Baftizadeh, F.; Campagnola, L.; Jarsky, T.; Koch, C.; Anastassiou, C. A.

10.1101/2023.02.14.528526 — neuroscience — Posted on 2024-03-04

4552 BrainBeats, an Open-Source EEGLAB Plugin to Jointly Analyze EEG and Cardiovascular Signals

Cannard, C.; Wahbeh, H.; Delorme, A.

10.1101/2023.06.01.543272 — neuroscience — Posted on 2024-03-04

4553 Graph perceiver network for lung tumor and bronchial premalignant lesion stratification from histopathology

Gindra, R. H.; Zheng, Y.; Green, E. J.; Reid, M. E.; Mazzilli, S. A.; Merrick, D. T.; Burks, E. J.; Kolachalama, V. B.; Beane, J. E.

10.1101/2023.10.16.562550 — pathology — Posted on 2024-03-04

4554 CAMPER: curated annotations for profiling microbial polyphenol metabolic potential

McGivern, B. B.; Woyda, R.; Flynn, R. M.; Wrighton, K. C.

10.1101/2023.09.24.559193 — bioinformatics — Posted on 2024-03-04

4555 Compositional editing of extracellular matrices by CRISPR/Cas9 engineering of human mesenchymal stem cell lines

Prithiviraj, S.; Garcia Garcia, A.; Linderfalk, K.; Yiguang, B.; Ferveur, S.; Falck, L. N.; Subramaniam, A.; Mohlin, S.; Gil, D. H.; Dupard, S. J.; Raina, D. B.; Bourgine, P. E.

10.1101/2023.07.28.550935 — bioengineering — Posted on 2024-03-04

4556 Stochastic parabolic growth promotes coexistence and a relaxed error threshold in RNA-like replicator populations

Paczko, M.; Szathmary, E.; Szilagyi, A.

10.1101/2023.11.02.565370 — evolutionary biology — Posted on 2024-03-04

4557 Error causes a perceived pull to the present in evolutionary rates

O'Meara, B. C.; Beaulieu, J.

10.1101/2024.02.29.582777 — evolutionary biology — Posted on 2024-03-04

4558 Coxiella burnetii-containing vacuoles interact with host recycling-endosomal proteins Rab11a and Rab35 for vacuolar expansion

Hall, B. A.; Senior, K. E.; Ocampo, N. T.; Samanta, D.

10.1101/2024.03.01.582943 — microbiology — Posted on 2024-03-04

4559 Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract

McKay, L. S.; Spandrio, A. R.; Johnson, R. M.; Sobran, M. A.; Marlatt, S.; Mote, K. B.; Dedloff, M. R.; Nash, Z. M.; Julio, S. M.; Cotter, P. A.

10.1101/2024.02.29.582880 — microbiology — Posted on 2024-03-04

4560 Secreted antigen A peptidoglycan hydrolase is essential for Enterococcus faecium cell separation and priming of immune checkpoint inhibitor cancer therapy

Klupt, S.; Fam, K. T.; Zhang, X.; Chodisetti, P. K.; Mehmood, A.; Boyd, T.; Grotjahn, D.; Park, D.; Hang, H. C.

10.1101/2023.11.19.567738 — microbiology — Posted on 2024-03-04

4561 Biomechanical Costs Influence Decisions Made During Ongoing Actions

Canaveral, C. A.; Lata, W.; Green, A. M.; Cisek, P.

10.1101/2024.02.26.582113 — neuroscience — Posted on 2024-03-04

4562 Metabolic state modulates neural processing of odors in the human olfactory bulb

Iravani, B.; Frasnelli, J.; Arshamian, A.; Lundstrom, J. N.

10.1101/2023.08.23.554431 — neuroscience — Posted on 2024-03-04

4563 Metformin treatment results in distinctive skeletal muscle mitochondrial remodeling in rats with different intrinsic aerobic capacities

Bubak, M. P.; Davidyan, A.; O'Reilly, C. L.; Mondal, S. A.; Kest, J.; Doidge, S. M.; Borowik, A. K.; Taylor, M. T.; Voloviceva, E.; Kinter, M. T.; Britton, S. L.; Koch, L. G.; Stout, M. B.; Lewis, T. L.; Miller, B. F.

10.1101/2024.03.01.582957 — physiology — Posted on 2024-03-04

4564 Unveiling the genome assembly of the polyploid and quarantine root-knot nematode, Meloidogyne enterolobii

Poullet, M.; Gopal, H.; Rancurel, C.; Sallaberry, M.; Lopez-Roques, C.; Lledo, J.; Kiewnick, S.; Danchin, E.

10.1101/2024.03.01.582926 — genomics — Posted on 2024-03-04

4565 Times birds need to evolve mating cues under allopatry and parapatry

Sibly, R. M.; Curnow, R. N.

10.1101/2024.03.01.582980 — evolutionary biology — Posted on 2024-03-04

4566 Collective intelligence facilitates emergent resource partitioning through frequency dependent learning

Ogino, M.; Farine, D. R.

10.1101/2024.03.01.582983 — ecology — Posted on 2024-03-04

4567 Age- and Sex-Dependent Caveolar Gene Expression in Normoxic and Post-Ischemic Mouse Hearts

Kiessling, C. J.

10.1101/2024.03.01.582960 — molecular biology — Posted on 2024-03-04

4568 Exposure to live saprophytic Leptospira before challenge with a pathogenic serovar prevents severe leptospirosis and promotes kidney homeostasis

Kundu, S.; Shetty, A.; Gomes-Solecki, M.

10.1101/2024.03.01.582981 — immunology — Posted on 2024-03-04

4569 Localized estimation of event-related neural source activity from simultaneous MEG-EEG with a recurrent neural network

O'Reilly, J. A.; Zhu, J. D.; Sowman, P. F.

10.1101/2024.03.01.582924 — neuroscience — Posted on 2024-03-04

4570 The Molecular Determinants of a Universal Prion Acceptor

Arshad, H.; Patel, Z.; Al-Azzawi, Z. A. M.; Li, L.; Amano, G.; Mehra, S.; Eid, S.; Schmitt-Ulms, G.; Watts, J. C.

10.1101/2024.03.01.582976 — neuroscience — Posted on 2024-03-04

4571 Intermittent protein restriction elevates food intake and plasma ghrelin in male mice

Volcko, K. L.; Taghipourbibalan, H.; McCutcheon, J. E.

10.1101/2024.03.01.582931 — physiology — Posted on 2024-03-04

4572 An integrative approach to protein sequence design through multiobjective optimization

Hong, L.; Kortemme, T.

10.1101/2024.03.01.582670 — biophysics — Posted on 2024-03-04

4573 The power and limits of predicting exon-exon interactions using protein 3D structures

Liebold, J.; Del Moral-Morales, A.; Manalastas-Cantos, K.; Tsoy, O.; Kurtz, S.; Baumbach, J.; Newaz, K.

10.1101/2024.03.01.582917 — bioinformatics — Posted on 2024-03-04

4574 Community assesses differential cell communication using large multi-sample case-control scRNAseq datasets.

Solovey, M.; Celik, M. A.; Salcher, F. R.; Abdelfattah, M.; Ismail, M.; Scialdone, A.; Ziemann, F.; Colome-Tatche, M.

10.1101/2024.03.01.582941 — bioinformatics — Posted on 2024-03-04

4575 Thermal Characterization and Preclinical Validation of an Accessible, Carbon Dioxide-Based Cryotherapy System

Hu, Y.; Gordon, N.; Ogg, K.; Kraitchman, D. L.; Durr, N. J.; Surtees, B.

10.1101/2024.03.01.582967 — bioengineering — Posted on 2024-03-04

4576 A trait-based taxonomic data base for the order Schizomida (Arachnida) with descriptions of a new fossil species from Kachin amber and the female of Surazomus palenque Villarreal, Miranda & Giupponi 2016.

Müller, S. P.; De Francesco Magnussen, I.; Gearty, W.; Duperre, N.; Hammel, J. U.; Kotthoff, U.

10.1101/2024.03.01.582919 — evolutionary biology — Posted on 2024-03-04

4577 The community of Marine Alveolate parasites in the Atlantic inflow to the Arctic Ocean is structured by season, depth and water mass

Egge, E.; Vaulot, D.; Larsen, A.; Edvardsen, B.

10.1101/2024.03.01.582906 — ecology — Posted on 2024-03-04

4578 Last-century vegetation dynamics in a highland Pyrenean national park and implications for conservation

Rull, V.; Blasco, A.; Sigro, J.; Vegas-Vilarrubia, T.

10.1101/2024.03.01.582940 — ecology — Posted on 2024-03-04

4579 Something old, something new: the origins of an unusual renal cell underpinning a beetle water-conserving mechanism

Beaven, R.; Koyama, T.; Naseem, M. T.; Halberg, K. V.; Denholm, B.

10.1101/2024.03.01.582930 — developmental biology — Posted on 2024-03-04

4580 The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.

Lo Ying Ping, F.; Vahsen, T.; Brault, A.; Nere, R.; Labbe, S.

10.1101/2024.03.03.583214 — molecular biology — Posted on 2024-03-04

4581 Identification of Interaction Partners of Outer Inflammatory Protein A: Computational and Experimental Insights into How Helicobacter pylori Infects Host Cells

Akcelik-Deveci, S.; Kilic, E.; Mansur-Ozen, N.; Timucin, E.; Buyukcolak, Y.; Oktem-Okullu, S.

10.1101/2024.03.03.583189 — microbiology — Posted on 2024-03-04

4582 Wolbachia infection in Aedes aegypti does not affect its vectorial capacity for Dirofilaria immitis

Shirozu, T.; Regilme, M. A. F.; Ote, M.; Sasaki, M.; Soga, A.; Bochimoto, H.; Kawabata, H.; Umemiya-Shirafuji, R.; Kanuka, H.; Fukumoto, S.

10.1101/2024.03.04.583272 — microbiology — Posted on 2024-03-04

4583 The Interplay Between Nutrition and the Midgut Microbiome of the Mosquito Aedes aegypti Reveals Putative Symbionts.

Salgado, J. F. M.; Premkrishnan, B. N. V.; Oliveira, E. L.; Vettath, V. K.; Goh, F. G.; Hou, X.; Drautz-Moses, D. I.; Cai, Y.; Schuster, S. C.; M., A. C.

10.1101/2024.03.04.583003 — microbiology — Posted on 2024-03-04

4584 Contrasting patterns of Asaia sp association with Plasmodium falciparum between field collected Anopheles gambiae and Anopheles coluzzii from Cameroon

Sandeu, M. M.; Maffo, C. G. T.; Tchoupo, M.; Kamga, F. M. D.; Mugenzi, L. J.; Njiokou, F.; Hughes, G.; Wondji, C. S.

10.1101/2024.03.04.583377 — microbiology — Posted on 2024-03-04

4585 Addressing anemia severity in antimony-resistant Leishmania donovani infection at the nexus of oxidative outburst and iron transit

Ghosh, S.; Chigicherla, K. V.; Dasgupta, S.; Goto, Y.; Mukherjee, B.

10.1101/2024.03.04.583250 — microbiology — Posted on 2024-03-04

4586 Antibiotic Resistant Escherichia coli in Uncooked Meat Purchased from Large Chain Grocery Stores and in Raw Dog Food Purchased From Pet Stores in the Same City.

Sealey, J. E.; Astley, B.; Rollings, K.; Avison, M. B.

10.1101/2024.03.03.583175 — microbiology — Posted on 2024-03-04

4587 The complement regulator CD55 modulates TLR9 signaling and supports survival in marginal zone B cells

Lee, I.; Ling, I.; Verma, S.; Blanche, W.; Pham, C.; Kendall, P.

10.1101/2024.03.01.582833 — immunology — Posted on 2024-03-04

4588 Th17 cells with a pathogenic signature in joints of ZAP-70 mutant arthritic mice harbor unique TCR repertoires that share features with WT Tregs

Llamas-Covarrubias, M. A.; Tanaka, A.; Loza Lopez, M. d. J.; Diez, D.; Xu, Z.; Lim, E. L.; Teraguchi, S.; Sakaguchi, S.; Standley, D. M.

10.1101/2024.03.01.582868 — immunology — Posted on 2024-03-04

4589 Real-time control of a hearing instrument with EEG-based attention decoding

Hjortkjaer, J.; Wong, D. D. E.; Catania, A.; Marcher-Rorsted, J.; Ceolini, E.; Fuglsang, S. A.; Kiselev, I.; Di Liberto, G.; Liu, S.-C.; Dau, T.; Slaney, M.; de Cheveigne, A.

10.1101/2024.03.01.582668 — neuroscience — Posted on 2024-03-04

4590 Repeated Exposure Decreases Aesthetic Chills Likelihood but Increases Intensity

Schoeller, F.; Christov-Moore, L.; Lynch, C.; Jain, A.; Diot, T.; Reggente, N.

10.1101/2024.03.01.582918 — neuroscience — Posted on 2024-03-04

4591 Dorsal CA1 silencing degrades tactile short-term memory

Someck, S.; Katz, N.; Levi, A.; Stark, E.

10.1101/2024.03.01.582962 — neuroscience — Posted on 2024-03-04

4592 Photothrombosis induced cortical stroke produces electrographic epileptic biomarkers in mice

Shaw, D. C.; Kondabolu, K.; Walsh, K. G.; Shi, W.; Rillosi, E.; Hsiung, M.; Eden, U.; Richardson, R. M.; Kramer, M. A.; Chu, C. J.; Han, X.

10.1101/2024.03.01.582958 — neuroscience — Posted on 2024-03-04

4593 Astrocytic thrombospondins 1 and 2 are required for cortical synapse development controlling instrumental performance

Lawal, O. O.; Ulloa Severino, F. P.; Wang, S.; Bindu, D. S.; Sakers, K.; Johnson, S. A.; Yin, H. H.; Eroglu, C.

10.1101/2024.03.01.582935 — neuroscience — Posted on 2024-03-04

4594 Element accumulation in the tracheal and bronchial cartilages of monkeys

Azuma, C.; Oishi, T.; Tohno, Y.; Ke, L.; Zhao, X.-z.; Minami, T.; Horii-Hayashi, N.; Inoue, K.

10.1101/2024.03.01.582912 — zoology — Posted on 2024-03-04

4595 In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

Nguyen, T. N. T.; Martin, M.; Arpin, C.; Bernard, S.; Gandrillon, O.; Crauste, F.

10.1101/2024.03.01.582928 — systems biology — Posted on 2024-03-04

4596 A Targeted Genome-scale Overexpression Platform for Proteobacteria

Banta, A. B.; Myers, K. S.; Ward, R. D.; Cuellar, R. A.; Freeh, C. C.; Bacon, E. E.; Peters, J. M.

10.1101/2024.03.01.582922 — systems biology — Posted on 2024-03-04

4597 Rapid Identification of Genomic Alterations in Tumors affecting lymphocyte Infiltration (RIGATonI)

Vella, R.; Hoskins, E.; Yu, L.; Reeser, J. W.; Wing, M. R.; Samorodnitsky, E.; Stein, L.; Paruchuri, A.; ORIEN Investigators, ; Churchman, M.; Single, N.; Chen, W.; Freud, A. G.; Roychowdhury, S.

10.1101/2024.03.02.583103 — bioinformatics — Posted on 2024-03-04

4598 Revised Mechanism of Hydroxyurea Induced Cell Cycle Arrest and an Improved Alternative

Shaw, A. E.; Whitted, J. E.; Mihelich, M. N.; Reitman, H. J.; Timmerman, A. J.; Schauer, G. D.

10.1101/2024.03.02.583010 — biochemistry — Posted on 2024-03-04

4599 Juvenile Atlantic sturgeon survival and movement in proximity to an active cutterhead suction dredge

Balazik, M.; Clarke, D.

10.1101/2024.03.01.582914 — animal behavior and cognition — Posted on 2024-03-04

4600 Activation of the imprinted Prader-Willi Syndrome locus by CRISPR-based epigenome editing

Rohm, D.; Black, J. B.; McCutcheon, S. R.; Barrera, A.; Morone, D. J.; Nuttle, X.; de Esch, C. E.; Tai, D. J. C.; Talkowski, M. E.; Iglesias, N.; Gersbach, C. A.

10.1101/2024.03.03.583177 — genomics — Posted on 2024-03-04

4601 Repeated loss of function at HD mating-type genes and of recombination suppression without mating-type locus linkage in anther-smut fungi

Lucotte, E. A.; Jay, P.; Rougemont, Q.; Boyer, L.; Cornille, A. A.; Snirc, A.; Labat, A.; Chahine, E.; Duhamel, M.; Gendelman, J.; Hayes, R. K.; Perlin, M. H.; Hood, M.; Rodriguez de la Vega, R. C.; Giraud, T.

10.1101/2024.03.03.583181 — evolutionary biology — Posted on 2024-03-04

4602 Detection of pathogens and antimicrobial resistant genes from urine within 5 hours using Nanopore sequencing

Bellankimath, A. B.; Chapagain, C.; Branders, S.; Ali, J.; Wilson, R. C.; Johansen, T. E. B.; Ahmad, R.

10.1101/2024.03.04.582689 — microbiology — Posted on 2024-03-04

4603 A resource to enable chemical biology and drug discovery of WDR Proteins

Arrowsmith, C. H.; Ackloo, S.; Li, F.; Szewczyk, M.; Seitova, A.; Loppnau, P.; Zeng, H.; Ahmad, S.; Beldar, S.; Bolotokova, A.; Chau, I.; Dehghani-Tafti, S.; Dong, A.; Ghiabi, P.; Gibson, E.; Green, S. R.; Herasymenko, O.; Houliston, S.; Hutchinson, A.; Kimani, S. W.; Kutera, M.; Kwak, H. A.; Li, Y.; Machado, R. A.; Perveen, S.; Righetto, G. L.; Shrestha, S.; Silva, M.; Yadav, M.; Yazdi, A. K.; Santhakumar, V.; Edwards, A. M.; Barsyte-Lovejoy, D.; Schapira, M.; Brown, P. J.; Halabelian, L.; Xu, J.; Feng, J. A.; Kearnes, S.; Thompson, J.; Torng, W.; Gilmer, J.; Riley, P.; Watson, I.; Arnautova,

10.1101/2024.03.03.583197 — biochemistry — Posted on 2024-03-04

4604 Crystal structure of Bifidobacterium bifidum glycoside hydrolase family 110 α-galactosidase specific for blood group B antigen

Kashima, T.; Akama, M.; Wakinaka, T.; Arakawa, T.; Ashida, H.; Fushinobu, S.

10.1101/2024.03.03.583176 — biochemistry — Posted on 2024-03-04

4605 The Role of the Co-Chaperone DNAJB11 in Polycystic Kidney Disease: Molecular Mechanisms and Cellular Origin of Cyst Formation

Busch, T.; Neubauer, B.; Schmitt, L.; Cascante, I.; Knoblich, L.; Wegehaupt, O.; Schoeler, F.; Tholen, S.; Hofherr, A.; Schell, C.; Schilling, O.; Westermann, L.; Kottgen, M.

10.1101/2024.03.04.582938 — molecular biology — Posted on 2024-03-04

4606 Engineering customized viral receptors for various coronaviruses

Liu, P.; Huang, M.; Guo, H.; Si, J.; Chen, Y.; Wang, C.; Yu, X.; Shi, L.; Xiong, Q.; Ma, C.; Tong, F.; Liu, C.; Chen, J.; Guo, M.; Li, J.; Shi, Z.-L.; Yan, H.

10.1101/2024.03.03.583237 — microbiology — Posted on 2024-03-04

4607 Immunogenicity and safety of a live-attenuated SARS-CoV-2 vaccine candidate based on multiple attenuation mechanisms

Suzuki, M.; Okamura, S.; Gis, T.; Sasaki, H.; Lee, S.; Yoshida, A.; Goto, S.; Nakagawa, T.; Ikawa, M.; Kamitani, W.; Takekawa, S.; Yamanishi, K.; Ebina, H.

10.1101/2024.03.03.582873 — microbiology — Posted on 2024-03-04

4608 Cryo-EM Structure of the R388 plasmid conjugative pilus reveals a helical polymer characterised by an unusual pilin/phospholipid binary complex

Waksman, G.; Vadakeppat, A.; Xue, S.; Redzej, A.; Smith, T.; Ho, B.

10.1101/2024.03.04.583355 — microbiology — Posted on 2024-03-04

4609 Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation

Chatterjee, P.; Garcia, M.; Cote, J.; Yun, K.; Legerme, G.; Habib, R.; Tripepi, M.; Young, C.; Kulp, D. W.; Dyall-Smith, M.; Pohlschroder, M.

10.1101/2024.03.04.583388 — microbiology — Posted on 2024-03-04

4610 Identification of Southeast Asian Anopheles mosquito species using MALDI-TOF mass spectrometry

Chaumeau, V.; Piarroux, M.; Kulabkeeree, T.; Sawasdichai, S.; Inta, A.; Watthanaworawit, W.; Nosten, F.; Piarroux, R.; Nabet, C.

10.1101/2024.03.04.583274 — microbiology — Posted on 2024-03-04

4611 Bsp22 protein polymerization drives dynamic adaptation of the Bordetella type III secretion system injectisome

Malcova, I.; Kamanova, J.

10.1101/2024.03.04.583273 — microbiology — Posted on 2024-03-04

4612 The catabolism of alanine and glutamate ensure proper sporulation by respectively preventing premature germination and providing energy sources

Lyu, F.; Zhang, T.; Yang, D.; Gui, M.; Wang, Y.; Liao, X.; Rao, L.

10.1101/2024.03.04.583258 — microbiology — Posted on 2024-03-04

4613 Uncovering the class II-bacteriocin predatiome in salivarius streptococci

Damoczi, J.; Knoops, A.; Martou, M.-S.; Jamaux, F.; Gabant, P.; Mahillon, J.; Mignolet, J.; Hols, P.

10.1101/2024.03.04.583286 — microbiology — Posted on 2024-03-04

4614 A role for the S4-domain containing protein YlmH in ribosome-associated quality control in Bacillus subtilis

Takada, H.; Paternoga, H.; Fujiwara, K.; Nakamoto, J. A.; Park, E. N.; Dimitrova-Paternoga, L.; Beckert, B.; Saarma, M.; Tenson, T.; Buskirk, A.; Atkinson, G. C.; Chiba, S.; Wilson, D. N.; Hauryliuk, V.

10.1101/2024.03.03.583159 — microbiology — Posted on 2024-03-04

4615 Integrative in vivo analysis of the ethanolamine utilization bacterial microcompartment in Escherichia coli.

Jallet, D.; Soldan, V.; Shayan, R.; Stella, A.; Ismail, N.; Zenati, R.; Cahoreau, E.; Schiltz, O.; Balor, S.; Millard, P.; Heux, S.

10.1101/2024.03.04.583360 — microbiology — Posted on 2024-03-04

4616 Heterogeneous hybrid immunity against Omicron variant JN.1 at 11 months following breakthrough infection

He, X.; Jiang, J.; Li, G.; Liu, J.; Gan, J.; Zhou, L.; Bai, C.; Zi, Q.; Mou, X.; Zeng, S.; Yuan, J.; Zhou, C.; Li, Y.; Zhu, G.; Zhao, R.; Yang, L.; Wu, J.; Zhang, H.; Xian, J.; Wang, Z.; Qi, Q.; Liu, Y.; Yu, J.; Liu, D.; Li, W.

10.1101/2024.03.02.583082 — immunology — Posted on 2024-03-04

4617 Physics-driven structural docking and protein language models accelerate antibody screening and design for broad-spectrum antiviral therapy

Mubarak, H. F.; Tan, W.; Hoffmann, A. D.; Wei, J.; El-Shennawy, L.; Squires, J. R.; Sun, Y.; Dashzeveg, N. K.; Simonton, B.; Jia, Y.; Iyer, R.; Xu, Y.; Nicolaescu, V.; Elli, D.; Randall, G. C.; Schipma, M. J.; Swaminathan, S.; Ison, M. G.; Liu, H.; Fang, D.; Shen, Y.

10.1101/2024.03.01.582176 — immunology — Posted on 2024-03-04

4618 Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate AVX/COVID-12 Activates T Cells and Is Recognized by Antibodies from COVID-19 Patients and Vaccinated

Torres-Flores, A.; Ontiveros-Padilla, L. A.; Madera-Sandoval, R. L.; Tepale-Segura, A.; Gajon-Martinez, J.; Rivera-Hernandez, T.; Ferat-Osorio, E. A.; Cerbulo-Vazquez, A.; Arriaga-Pizano, L. A.; Bonifaz, L.; Paz-De la Rosa, G.; Rojas-Martinez, O.; Suarez-Martinez, A.; Peralta-Sanchez, G.; Sarfati-Mizrahi, D.; Sun, W.; Chagoya-Cortes, H. E.; Palese, P.; Krammer, F.; Garcia-Sastre, A.; Lozano-Dubernard, B.; Lopez-Macias, C.

10.1101/2024.03.01.582987 — immunology — Posted on 2024-03-04

4619 B cell maturation restored ancestral germlines to control Omicron BA.2.86

Paciello, I.; Pierleoni, G.; Pantano, E.; Antonelli, G.; Pileri, P.; Maccari, G.; Cardamone, D.; Realini, G.; Perrone, F.; Neto, M. M.; Pozzessere, S.; Fabbiani, M.; Panza, F.; Rancan, I.; Tumbarello, M.; Montagnani, F.; Medini, D.; Maes, P.; Temperton, N. J.; Simon-Loriere, E.; Schwartz, O.; Rappuoli, R.; Andreano, E.

10.1101/2024.03.03.583187 — immunology — Posted on 2024-03-04

4620 Time-dependent enhancement of mRNA vaccines by 4-1BB costimulation

Sanchez, S.; Dangi, T.; Awakoaiye, B.; Irani, N.; Fourati, S.; Richner, J. M.; Penaloza-MacMaster, P.

10.1101/2024.03.01.582992 — immunology — Posted on 2024-03-04

4621 Proteome-scale tissue mapping using mass spectrometry based on label-free and multiplexed workflows

Kwon, Y.; Woo, J.; Yu, F.; Williams, S. M.; Markillie, L. M.; Moore, R. J.; Nakaysu, E. S.; Chen, J.; Campbell-Thompson, M.; Mathews, C. E.; Nesvizhskii, A. I.; Qian, W.-J.; Zhu, Y.

10.1101/2024.03.04.583367 — systems biology — Posted on 2024-03-04

4622 Pervasive mitochondrial tRNA gene loss in the clade B of haplosclerid sponges (Porifera, Demospongiae).

Lavrov, D. V.; Turner, T. L.; Vicente, J.

10.1101/2024.03.04.583380 — evolutionary biology — Posted on 2024-03-04

4623 Cerebellar granule cell migration and folia development requires Mllt11/Af1q/Tcf7c

Blommers, M.; Stanton-Turcotte, D.; Witt, E. A.; Heidari, M.; Iulianella, A.

10.1101/2023.09.12.557458 — developmental biology — Posted on 2024-03-04

4624 Molecular Speciation of Cyathostomins From Horses In Ireland

Byrne, O.; Gangotia, D.; Crowley, J.; Zintl, A.; Kiser, L.; McSweeney, D.; Lamb, B.-R.; O'Neill, F.; Dunne, S.; Boxall, O.; Walshe, N.; Mulcahy, G.

10.1101/2023.12.13.571572 — molecular biology — Posted on 2024-03-04

4625 Systematic classification of phage receptor-binding proteins predicts surface glycopolymer structure in Staphylococcus pathogens

Krusche, J.; Beck, C.; Lehmann, E.; Gerlach, D.; Wolz, C.; Peschel, A.

10.1101/2024.03.04.583386 — microbiology — Posted on 2024-03-04

4626 Inflamed Natural Killer cells with adhesion defects are associated with a poor prognosis in Multiple Myeloma

Blanquart, E.; Ekren, R.; Rigaud, B.; Joubert, M.-V.; Baylot, V.; Daunes, H.; Cuisinier, M.; Villard, M.; Carrie, N.; Mazzotti, C.; Lucca, L. E.; Perrot, A.; Corre, J.; Walzer, T.; Avet-Loiseau, H.; Axisa, P.-P.; Martinet, L.

10.1101/2024.01.15.575654 — immunology — Posted on 2024-03-04

4627 Omissions of Threat Trigger Subjective Relief and Prediction Error-Like Signaling in the Human Reward and Salience Systems

Willems, A. L.; Van Oudenhove, L.; Vervliet, B.

10.1101/2023.08.15.553434 — neuroscience — Posted on 2024-03-04

4628 Periplasmic carbonic anhydrase CAH1 contributes to high inorganic carbon affinity in Chlamydomonas reinhardtii

Shimamura, D.; Ikeuchi, T.; Tsuji, Y.; Fukuzawa, H.; Yamano, T.

10.1101/2024.03.04.583368 — plant biology — Posted on 2024-03-04

4629 HTLV-1 infected T cells cause bone loss via small extracellular vesicles

Pokhrel, N. K.; Panfil, A.; Habib, H.; Seeniraj, S.; Joseph, A.; Rauch, D.; Sprung, R.; Gilmore, P. E.; Zhang, Q.; Townsend, R. R.; Yu, L.; Yilmaz, A. S.; Aurora, R.; Park, W.; Ratner, L.; Weilbaecher, K. N.; Veis, D. J.

10.1101/2024.02.29.582779 — cancer biology — Posted on 2024-03-04

4630 Stabilization of AMPK/PFKL/RPIA in the Glycolytic Bodies Transduces IL6/STAT3 Signal in Hepatocarcinogenesis

Hsiao, H.-Y.; Cheng, C.-C.; Chou, Y.-T.; Kuo, C.-C.; Wang, W.-C.; Sampurna, B. P.; Wang, Y.-W.; Hsiao, C.-L.; Wu, J.-Y.; Lin, K.-H.; Yang, W.-Y.; Lin, Y.-H.; Gwee, K.-H.; Wang, H.-D.; Yuh, C.-H.

10.1101/2024.02.29.582877 — cancer biology — Posted on 2024-03-04

4631 Brain-wide neuronal circuit connectome of human glioblastoma

Sun, Y.; Wang, X.; Zhang, D. Y.; Zhang, Z.; Bhattarai, J. P.; Wang, Y.; Dong, W.; Zhang, F.; Park, K. H.; Galanaugh, J.; Sambangi, A.; Yang, Q.; Kim, S. H.; Wheeler, G.; Goncalves, T.; Wang, Q.; Geschwind, D.; Kawaguchi, R.; Wang, H.; Xu, F.; Binder, Z. A.; Chen, I. H.; Pai, E. L.-L.; Stone, S.; Nasrallah, M.; Christian, K. M.; Fuccillo, M.; O'Rourke, D. M.; Ma, M.; Ming, G.-l.; Song, H.

10.1101/2024.03.01.583047 — cancer biology — Posted on 2024-03-04

4632 Targeting GFPT2 to reinvigorate immunotherapy in EGFR-mutated NSCLC

Ao, L.; Jia, W.; Gong, Q.; Cui, J.; Wang, J.; Yu, Y.; Fu, C.; Li, H.; Wei, J.; Wang, R.; Wang, F.; Shang, X.; Li, Y.; Fang, S.; Wang, G.; Zhou, F.; Liu, J.

10.1101/2024.03.01.582888 — cancer biology — Posted on 2024-03-04

4633 Surface adhesion and membrane fluctuations influence the elastic modulus of extracellular vesicles

Stridfeldt, F.; Kylhammar, H.; Metem, P.; Pandey, V.; Agrawal, V.; Gorgens, A.; Mamand, D. R.; Gustafsson, O.; El Andaloussi, S.; Mitra, D.; Dev, A.

10.1101/2024.02.07.578591 — biophysics — Posted on 2024-03-04

4634 The global β-lactam resistome revealed by comprehensive sequence analysis

Gholipour, S.; Chen, J.; Lee, D.; Tokuriki, N.

10.1101/2024.03.01.583042 — bioinformatics — Posted on 2024-03-04

4635 Accelerating de novo SINE annotation in plant and animal genomes

Liao, H.; Ou, S.; Sun, Y.

10.1101/2024.03.01.582874 — bioinformatics — Posted on 2024-03-04

4636 Integrating Knowledge Graphs into Machine Learning Models for Survival Prediction and Biomarker Discovery in Patients with Non-Small-Cell Lung Cancer

Fang, C.; Arango Argoty, G. A.; Kagiampakis, I.; Khalid, M. H.; Jacob, E.; Bulusu, K.; Markuzon, N.

10.1101/2024.02.29.582842 — bioinformatics — Posted on 2024-03-04

4637 A novel model-free feature selection method with FDR control for omics-wide association analysis

Lu, Z.-t.; Song, X.-t.; Gao, Y.-f.; Xiao, J.

10.1101/2024.03.01.582911 — bioinformatics — Posted on 2024-03-04

4638 Healthy microbiome - moving towards functional interpretation

Zielinska, K.; Udekwu, K.; Rudnicki, W.; Frolova, A.; Kosciolek, T.; Labaj, P. P.

10.1101/2023.12.04.569909 — bioinformatics — Posted on 2024-03-04

4639 Comprehensive analysis of CXXX sequence space reveals that S. cerevisiae GGTase-I mainly relies on a2X substrate determinants

Schmidt, W. K.; Sarkar, A.; Hildebrandt, E. R.; Patel, K. V.; Mai, E. T.; Shah, S. S.; Kim, J. H.

10.1101/2024.03.04.583369 — genetics — Posted on 2024-03-04

4640 Genomic evidence reveals three sequential W-autosome fusions in Heliconius butterflies

Rueda-M, N.; Pardo-Diaz, C.; Montejo-Kovacevich, G.; McMillan, W. O.; Kozak, K. M.; Arias, C. F.; Ready, J.; McCarthy, S.; Durbin, R.; Jiggins, C. D.; Meier, J.; Salazar, C.

10.1101/2023.03.06.531374 — evolutionary biology — Posted on 2024-03-04

4641 Characterization of early and late events of adherens junction assembly

Troyanovsky, R. B.; Indra, I.; Troyanovsky, S. M.

10.1101/2024.03.04.583373 — cell biology — Posted on 2024-03-04

4642 Critical factors for precise and efficient RNA cleavage by RNase Y in Staphylococcus aureus

Le Scornet, A.; Jousselin, A.; Baumas, K.; Kostova, G.; Durand, S.; Poljak, L.; Barriot, R.; Coutant, E.; Pellisier, C.; Munoz, G.; Condon, C.; Redder, P.

10.1101/2023.08.22.554078 — molecular biology — Posted on 2024-03-04

4643 Evaluation Of Suitability Analysis of Gangetic Water from Upper, Middle, And Lower Ganga Rivers

Balkrishna, A.; Singh, S.; Nagose, A.; Joshi, D.; Kannojia, K.; Taneja, S.; Saxena, A.; Arya, V.; Ghosh, S.

10.1101/2024.02.28.582642 — microbiology — Posted on 2024-03-04

4644 Cellulose fermentation by the gut microbiota is likely not essential for the nutrition of millipedes

Angel, R.; Nweze, J. E.; Gupta, S.; Salcher, M. M.; Sustr, V.; Horvathova, T.

10.1101/2024.03.01.582937 — microbiology — Posted on 2024-03-04

4645 On the Evolution of Chromosomal Regions with High Gene Strand Bias in Bacteria

Tomasch, J.; Kopejtka, K.; Shivaramu, S.; Mujakic, I.; Koblizek, M.

10.1101/2024.02.28.582576 — microbiology — Posted on 2024-03-04

4646 Predicting bacterial interaction outcomes from monoculture growth and supernatant assays

Schmitz, D. A.; Wechsler, T.; Mignot, I.; Kuemmerli, R.

10.1101/2023.07.03.547502 — microbiology — Posted on 2024-03-04

4647 A locally administered single cycle influenza vaccine expressing a non-fusogenic stabilised haemagglutinin stimulates strong T-cell and neutralising antibody immunity

Sadler, H.; Rijal, P.; Tan, T. K.; Townsend, A. R.

10.1101/2024.03.01.582898 — immunology — Posted on 2024-03-04

4648 Activating soluble adenylyl cyclase protects mitochondria, rescues retinal ganglion cells, and ameliorates visual dysfunction caused by oxidative stress

Bastola, T.; Perkins, G. A.; Huu, V. A. N.; Ju, S.; Kim, K.-Y.; Shen, Z.; Skowronska-Krawczyk, D.; Weinreb, R. N.; Ju, W.-K.

10.1101/2024.03.04.583371 — neuroscience — Posted on 2024-03-04

4649 A Methodology for Specific Disruption of Microtubules in Dendritic Spines

Holland, E. D.; Miller, H. L.; Millette, M. M.; Taylor, R. J.; Drucker, G. L.; Dent, E. W.

10.1101/2024.03.04.583370 — neuroscience — Posted on 2024-03-04

4650 Functional Diversity of Dopamine Axons in Prefrontal Cortex During Classical Conditioning

Abe, K.; Kambe, Y.; Majima, K.; Hu, Z.; Ohtake, M.; Momennezhad, A.; Izumi, H.; Tanaka, T.; Matunis, A.; Stacy, E.; Itokazu, T.; Sato, T. R.; Sato, T. K.

10.1101/2023.08.23.554475 — neuroscience — Posted on 2024-03-04

4651 Developing Bioactive Hydrogels Containing Cell-derived Extracellular Matrix: Implications in Drug and Cell-free Bone and Cartilage Repair

Coyle, A.; Chakraborty, A.; Huang, J.; Shamiya, Y.; Luo, W.; Paul, A.

10.1101/2024.03.04.583366 — bioengineering — Posted on 2024-03-04

4652 Structural insights in the GTP-driven monomerization and activation of a bacterial LRRK2 homologue using allosteric nanobodies

Galicia, C.; Guaitoli, G.; Fislage, M.; Gloeckner, C. J.; Versees, W.

10.1101/2023.11.13.566844 — biochemistry — Posted on 2024-03-04

4653 Discarded sequencing reads uncover natural variation in pest resistance in Thlaspi arvense

Galanti, D.; Jung, J. H.; Müller, C.; Bossdorf, O.

10.1101/2023.10.17.562203 — evolutionary biology — Posted on 2024-03-04

4654 The left posterior angular gyrus is engaged by autobiographical recall not object-semantics, or event-semantics: Evidence from contrastive propositional speech production

Humphreys, G. F.; Halai, A. D.; Branzi, F.; Lambon Ralph, M.

10.1101/2022.04.04.487000 — neuroscience — Posted on 2024-03-04

4655 Anatomical and functional organization of cardiac fibers in the porcine cervical vagus nerve allows spatially selective efferent neuromodulation

Thompson, N.; Ravagli, E.; Mastitskaya, S.; Challita, R.; Hadaya, J.; Iacoviello, F.; Shah Idil, A.; Shearing, P. R.; Ajijola, O. A.; Ardell, J. L.; Shivkumar, K.; Holder, D.; Aristovich, K.

10.1101/2024.01.09.574861 — neuroscience — Posted on 2024-03-04

4656 Neuronal Network Dynamics in the Posterodorsal Amygdala: Shaping Reproductive Hormone Pulsatility

Nechyporenko, K.; Voliotis, M.; Li, X. F.; Hollings, O.; Ivanova, D.; Walker, J. J.; O'Byrne, K. T.; Tsaneva-Atanasova, K.

10.1101/2024.01.21.574304 — neuroscience — Posted on 2024-03-04

4657 Expanding the genetic toolbox for the obligate human pathogen Streptococcus pyogenes

Lautenschlaeger, N.; Schmidt, K.; Schiffer, C.; Wulff, T. F.; Hahnke, K.; Finstermeier, K.; Mansour, M.; Elsholz, A. K. W.; Charpentier, E.

10.1101/2024.03.04.582890 — synthetic biology — Posted on 2024-03-04

4658 LHP1 and INO80 cooperate with ethylene signaling for warm ambient temperature response by activating specific bivalent genes

Shao, Z.; Bai, Y.; Huq, E.; Qiao, H.

10.1101/2024.03.01.583049 — plant biology — Posted on 2024-03-04

4659 Impact of alternative splicing on Arabidopsis proteome

Reyes, A. V.; Shrestha, R.; Grismer, T. S.; Byun, D.; Xu, S.

10.1101/2024.02.29.582853 — plant biology — Posted on 2024-03-04

4660 ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability

Zhang, B.; Huang, S.; Guo, S.; Meng, Y.; Tian, Y.; Zhou, Y.; Chen, H.; Li, X.; Zhou, J.; Chen, W.

10.1101/2024.02.29.582862 — plant biology — Posted on 2024-03-04

4661 pTAC3 and pTAC14 are required for binding of plastid-encoded RNA polymerase to DNA

Wang, J.; Palomar, M.; Min, J.-H.; Wierzbicki, A.

10.1101/2024.03.01.582956 — plant biology — Posted on 2024-03-04

4662 Comparison of a novel potentiator of CFTR channel activity to ivacaftor in ameliorating mucostasis caused by cigarette smoke in primary human bronchial airway epithelial cells

Tanjala, A. C.; Jiang, J. X.; Eckford, P. D. W.; Ramjeesingh, M.; Li, C.; Huan, L. J.; Langeveld, G.; Townsend, C.; Paone, D.; Busch Petersen, J.; Pekhletski, R.; Tang, L.; Raju, V.; Rowe, S. M.; Bear, C.

10.1101/2024.03.01.582742 — physiology — Posted on 2024-03-04

4663 Bilayered Biofabrication Unlocks the Potential of Skeletal Muscle for Biohybrid Soft Robots

Balciunaite, A.; Yasa, O.; Filippi, M.; Michelis, M.; Katzschmann, R.

10.1101/2024.03.01.582738 — bioengineering — Posted on 2024-03-04

4664 Effects of input image size on the accuracy of fish identification using deep learning.

Iwahara, Y.; Shibata, Y.; Manano, M.; Nishino, T.; Kariya, R.; Yaemori, H.

10.1101/2024.03.01.582886 — ecology — Posted on 2024-03-04

4665 Prioritizing replay when future goals are unknown

Sagiv, Y.; Akam, T.; Witten, I.; Daw, N. D.

10.1101/2024.02.29.582822 — neuroscience — Posted on 2024-03-04

4666 Assessing the Effects of Various Physiological Signal Modalities on Predicting Different Human Cognitive States

Aygun, A.; Nguyen, T. D.; Scheutz, M.

10.1101/2024.02.29.582708 — neuroscience — Posted on 2024-03-04

4667 Frequency-tagging of spatial attention using periliminal flickers

Ladouce, S.; Dehais, F.

10.1101/2024.02.29.582725 — neuroscience — Posted on 2024-03-04

4668 Remembrance with gazes passed: Eye movements precede continuous recall of episodic details of real-life events

Barker, R. M.; Armson, M. J.; Diamond, N. B.; Liu, Z.-X.; Wang, Y.; Ryan, J. D.; Levine, B.

10.1101/2024.02.29.582757 — neuroscience — Posted on 2024-03-04

4669 Synfire Chain Dynamics Unravelling Theta-nested Gamma Oscillations for Balancing Prediction and Dodge in Navigation

LI, K. T.; Wei, Y.; Gong, P.; Yang, D.

10.1101/2024.03.01.583075 — neuroscience — Posted on 2024-03-04

4670 ADP-dependent platelet activation is required for thrombus formation during a long-distance flight

Tour,, J.; Carminita, E.; Bruzzese, L.; Crescence, L.; Adjiriou, N.; Guieu, R.; Dubois, C.; Panicot-Dubois, L.

10.1101/2024.03.01.582882 — pathology — Posted on 2024-03-04

4671 Scvi-hub: an actionable repository for model-driven single cell analysis

Ergen, C.; Pour Amiri, V. V.; Kim, M.; Streets, A.; Gayoso, A.; Yosef, N.

10.1101/2024.03.01.582887 — bioinformatics — Posted on 2024-03-04

4672 Synthesis of arbitrary interference patterns using a single galvanometric mirror, and its application to Structured Illumination Microscopy

Guo, K.; Boualam, A.; Manton, J. D.; Rowlands, C. J.

10.1101/2024.02.29.582785 — bioengineering — Posted on 2024-03-04

4673 Sexually dimorphic renal expression of Klotho is directed by a kidney-specific distal enhancer responsive to HNF1b

Jankowski, J.; Lee, H. K.; Liu, C.; Wilflingseder, J.; Hennighausen, L.

10.1101/2024.02.29.582831 — genetics — Posted on 2024-03-04

4674 Identification of the host reservoir of SARS-CoV-2 and determining when it spilled over into humans

Pamjula, V.; Strachan, N. J. C.; Perez-Reche, F. J.

10.1101/2023.11.25.568670 — evolutionary biology — Posted on 2024-03-04

4675 On-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures

Onal, S.; Alkaisi, M. M.; Nock, V.

10.1101/2024.02.28.582630 — cell biology — Posted on 2024-03-04

4676 PI3K-dependant reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes

Paradoski, B.; Hou, S.; Mejia, E.; Adefemi-Olayinka, F.; Fowke, D.; Hatch, G. M.; Saleem, A.; Banerji, V.; Hay, N.; Zeng, H.; Marshall, A.

10.1101/2024.02.29.582554 — immunology — Posted on 2024-03-04

4677 Alpha-synuclein regulates the repair of genomic DNA double-strand breaks in a DNA-PKcs-dependent manner

Rose, E. P.; Osterberg, V. R.; Banga, J. S.; Gorbunova, V.; Unni, V. K.

10.1101/2024.02.29.582819 — neuroscience — Posted on 2024-03-04

4678 Social transmission of inflammation in mice

Quintana, S. C.; da Rosa, P. B.; Shionoya, K.; Blomqvist, A.; Engblom, D.

10.1101/2024.02.29.582723 — neuroscience — Posted on 2024-03-04

4679 Delineating Transdiagnostic Subtypes in Neurodevelopmental Disorders via Contrastive Graph Machine Learning of Brain Connectivity Patterns

Wang, X.; Zhao, K.; Yao, L.; Fonzo, G. A.; Satterthwaite, T. D.; Rekik, I.; Zhang, Y.

10.1101/2024.02.29.582790 — neuroscience — Posted on 2024-03-04

4680 Machine learning-based spike sorting reveals how subneuronal concentrations of monomeric Tau cause a loss in excitatory postsynaptic currents in hippocampal neurons

Brockhoff, M.; Träuble, J.; Middya, S.; Fuchsberger, T.; Fernandez-Villegas, A.; Stephens, A. D.; Robbins, M.; Dai, W.; Haider, B.; Vora, S.; Läubli, N. F.; Kaminski, C. F.; Malliaras, G. G.; Paulsen, O.; Schierle, G. S. K.

10.1101/2024.02.29.582792 — neuroscience — Posted on 2024-03-04

4681 Prostaglandin D2 synthase controls Schwann cells metabolism

Trimarco, A.; Audano, M.; La Marca, R.; Cariello, M.; Falco, M.; Pedretti, S.; Imperato, G.; Cestaro, A.; Podini, P.; Dina, G.; Quattrini, A.; Massimino, L.; Caruso, D.; Mitro, N.; Taveggia, C.

10.1101/2024.02.29.582775 — neuroscience — Posted on 2024-03-04

4682 Specifying the orthographic prediction error for a better understanding of efficient visual word recognition in humans and machines

Fu, W.; Gagl, B.

10.1101/2024.02.29.582776 — neuroscience — Posted on 2024-03-04

4683 Measuring instability in chronic human intracortical neural recordings towards stable, long-term brain-computer interfaces

Pun, T. K.; Khoshnevis, M.; Hosman, T.; Wilson, G. H.; Kapitonava, A.; Kamdar, F.; Henderson, J. M.; Simeral, J. D.; Vargas-Irwin, C. E.; Harrison, M. T.; Hochberg, L. R.

10.1101/2024.02.29.582733 — neuroscience — Posted on 2024-03-04

4684 Quadriceps-hamstrings muscle co-activation during the swing phase of walking is modulated by task constraints in healthy adults

Van Can, E. A. M.; Houdijk, H.; Buurke, T. J. W.

10.1101/2024.02.29.582454 — neuroscience — Posted on 2024-03-04

4685 miR-155-5p/miR-674-3p presence in peripheral blood leukocytes and relative proportion of white blood cell types as biomarkers of asymptomatic and symptomatic phases of temporal lobe epilepsy

Szydlowska, K.; Chroscicki, P.; Olszewski, M.; Nizinska, K.; Piwocka, K.; Lukasiuk, K.

10.1101/2024.02.29.582734 — neuroscience — Posted on 2024-03-04

4686 Redox regulation by the CDSP32 thioredoxin of ATP-synthase activity and enzymatic antioxidant network in Solanum tuberosum

Rey, P.; Henri, P.; Alric, J.; Blanchard, L.; Viola, S.

10.1101/2024.02.29.582824 — plant biology — Posted on 2024-03-04

4687 Proteomic profiling of IDH-wildtype Glioblastoma Tissue and Serum uncovers prognostic Subtypes and Marker Candidates

Werner, T.; Schaefer, A.; Hennes, M.; Cosenza Contreras, M.; Espadas, G.; Sabido, E.; Cook, L.; Pagenstecher, A.; Pinter, N.; Feilen, T.; Grote, A.; Nimsky, C.; Bartsch, J. W.; Schilling, O.

10.1101/2024.02.29.582688 — cancer biology — Posted on 2024-03-04

4688 miR-155 expression and function in leukemic stem cells

Garzon, R.; Croce, C. M.

10.1101/2024.02.29.582835 — cancer biology — Posted on 2024-03-04

4689 High-resolution fleezers reveal duplex opening and stepwise assembly by an oligomer of the DEAD-box helicase Ded1p

Patrick, E. M.; Yadav, R.; Senanayake, K.; Cotter, K.; Putnam, A. A.; Jankowsky, E.; Comstock, M. J.

10.1101/2024.02.29.582829 — biophysics — Posted on 2024-03-04

4690 MASCARA: coexpression analysis in data from designed experiments

White, F.; Heintz-Buschart, A.; Dong, L.; Bouwmeester, H.; Westerhuis, J.; Smilde, A.

10.1101/2024.02.29.582876 — bioinformatics — Posted on 2024-03-04

4691 scIDPMs: Single-cell RNA-seq imputation using diffusion probabilistic models

zhang, z.; Liu, L.

10.1101/2024.02.29.582870 — bioinformatics — Posted on 2024-03-04

4692 Segmentation error aware clustering for highly multiplexed imaging

Lee, Y.; Chen, E. L. Y.; Chan, D. C. H.; Dinesh, A.; Afiuni-Zadeh, S.; Klamann, C.; Selega, A.; Mrkonjic, M.; Jackson, H. W.; Campbell, K. R.

10.1101/2024.02.29.582827 — bioinformatics — Posted on 2024-03-04

4693 Treatment with both TGF-β1 and PDGF-BB disrupts the stiffness-dependent myofibroblast differentiation of corneal keratocytes

Iyer, K. S.; Maruri, D. P.; Schmidtke, D. W.; Petroll, M.; Varner, V. D.

10.1101/2024.02.29.582803 — bioengineering — Posted on 2024-03-04

4694 Beta Cells Deficient for Renalase Counteract Autoimmunity by Shaping Natural Killer Cell Activity

Bode, K.; Wei, S.; Gruber, I.; Kissler, S.; Yi, P.

10.1101/2024.02.29.582816 — immunology — Posted on 2024-03-04

4695 Secondary microglia formation center in the human fetal brain

Song, C.; Chen, X.; Ji, R.; Liu, Y.; Zhang, L.; Gao, L.; He, Q.; Ma, L.; saiyin, H.

10.1101/2024.02.29.582659 — neuroscience — Posted on 2024-03-04

4696 Network Analysis of the Cerebrospinal Fluid Proteome Reveals Shared and Unique Differences Between Sporadic and Familial Forms of Amyotrophic Lateral Sclerosis

Trautwig, A. N.; Fox, E. J.; Dammer, E. B.; Shantaraman, A.; Ping, L.; Duong, D. M.; Levey, A. I.; Lah, J. J.; Fournier, C. N.; McEachin, Z. T.; Glass, J. D.; Seyfried, N. T.

10.1101/2024.02.29.582840 — neuroscience — Posted on 2024-03-04

4697 Two PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEINs are essential for management of the coenzyme in plants

Farkas, P.; Fitzpatrick, T. B.

10.1101/2024.03.03.583161 — plant biology — Posted on 2024-03-04

4698 Robotic Laser Tissue Soldering for Damage-free Soft Tissue Fusion Guided by Fluorescent Nanothermometry

Cipolato, O.; Leuthold, T.; Zaech, M.; Maennel, G.; Aegerter, S.; Sciascia, C.; Jessernig, A.; Sarcevic, S.; Rosendorf, J.; Liska, V.; Kundrat, D.; Quidant, R.; Herrmann, I. K.

10.1101/2024.02.29.582843 — bioengineering — Posted on 2024-03-04

4699 Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals

Palou-Marquez, G.; Supek, F.

10.1101/2024.02.29.582778 — genomics — Posted on 2024-03-04

4700 Regulation of immune signal integration and memory by inflammation-induced chromosome conformation

Daniel, B.; Chen, A. Y.; Sandor, K.; Zhang, W.; Miao, Z.; Lareau, C. A.; Yost, K. E.; Chang, H.; Satpathy, A.

10.1101/2024.02.29.582872 — genomics — Posted on 2024-03-04

4701 A Combination of Environmental and Landscape Variables Drive Movement and Habitat use in Two Anaxyrus sp. in the Eastern Coastal Plain

Ferentinos, A. M.; Check, C. E.; Windorf, O.; Leu, M.

10.1101/2024.02.29.582809 — ecology — Posted on 2024-03-04

4702 A novel method for fine-scale retrospective isotope analysis in mammals using eye lenses

Miura, K.; Matsubayashi, J.; Yoshimizu, C.; Takafumi, H.; Shirane, Y.; Mano, T.; Tsuruga, H.; Tayasu, I.

10.1101/2024.02.29.582866 — ecology — Posted on 2024-03-04

4703 Leukemia aggressiveness is driven by chromatin remodeling and expression changes of core regulators

Bonilla, G.; Morris, A.; Kundu, S.; Ducasse, A.; Jeffries, N. E.; Chetal, K.; Yvanovich, E. E.; Barghout, R.; Scadden, D.; Mansour, M.; Kingston, R. E.; Sykes, D. B.; Mercier, F. E.; Sadreyev, R. I.

10.1101/2024.02.29.582846 — molecular biology — Posted on 2024-03-04

4704 M. bovis PPD Enhances Respiratory Bioenergetics of Human vs. Bovine Macrophages

Bartens, M.-C.; Willcocks, S.; Werling, D.; Gibson, A. J.

10.1101/2024.02.29.582730 — immunology — Posted on 2024-03-04

4705 Gene expression and eQTL analysis reflect the heterogeneity in the inflammatory status of the duodenal epithelial lining in coeliac disease

Ramirez-Sanchez, A. D.; Zühlke, S.; Aguirre-Gamboa, R.; Vochteloo, M.; Franke, L.; Lundin, K. E. A.; Withoff, S.; Jonkers, I. H.

10.1101/2024.02.29.582756 — immunology — Posted on 2024-03-04

4706 Activation of locus coeruleus noradrenergic neuronsrapidly drives homeostatic sleep pressure

Silverman, D.; Chen, C.; Chang, S.; Bui, L.; Zhang, Y.; Raghavan, R.; Jiang, A.; Darmohray, D.; Sima, J.; Ding, X.; Li, B.; Ma, C.; Dan, Y.

10.1101/2024.02.29.582852 — neuroscience — Posted on 2024-03-04

4707 Brain orchestra under spontaneous conditions: Identifying communication modules from the functional architecture of area V1

Papadopouli, M.; Koniotakis, E.; Smyrnakis, I.; Savaglio, M. A.; Psilou, E.; Brozi, C.; Palagina, G.; Smirnakis, S. M.

10.1101/2024.02.29.582364 — neuroscience — Posted on 2024-03-04

4708 Explainable Deep Learning Framework: Decoding Brain Task and Prediction of Individual Performance in False-Belief Task at Early Childhood Stage

Bhavna, K.; Akhter, A.; Banerjee, R.; Roy, D.

10.1101/2024.02.29.582682 — neuroscience — Posted on 2024-03-04

4709 PKHD1L1 is required for stereocilia bundle maintenance, prolonged hearing function and enhanced resilience to noise exposure.

strelkova, O. S.; Osgood, R. T.; Tian, C. J.; Zhang, X.; Hale, E.; De-la-Torre, P.; Hathaway, D. M.; Indzhykulian, A. A.

10.1101/2024.02.29.582786 — neuroscience — Posted on 2024-03-04

4710 Low intensity repetitive transcranial magnetic stimulation enhances remyelination by newborn and surviving oligodendrocytes in the cuprizone model of toxic demyelination

Nguyen, P. T.; Makowiecki, K.; Lewis, T. S.; Fortune, A.; Clutterbuck, M.; Reale, L.; Taylor, B. V.; Rodger, J.; Cullen, C. L.; Young, K.

10.1101/2024.02.29.582855 — neuroscience — Posted on 2024-03-04

4711 Insulin-mediated suppression of fatty acid release predicts whole-body insulin resistance of glucose uptake and skeletal muscle insulin receptor activation

Schleh, M.; Ryan, B.; Ahn, C.; Ludzki, A.; Van Pelt, D.; Pitchford, L.; Chugh, O.; Luker, A. T.; Luker, K. E.; Samovski, D.; Abumrad, N.; Burant, C.; Horowitz, J.

10.1101/2024.02.29.582589 — physiology — Posted on 2024-03-04

4712 Systematic computer-aided disulfide design as a general strategy to stabilize prefusion class I fusion proteins

Gonzalez, K. J.; Yim, K.; Blanco, J. C.; Boukhvalova, M. S.; Strauch, E.-M.

10.1101/2024.02.29.582784 — bioengineering — Posted on 2024-03-04

4713 Sex differences in early human fetal brain development

Buonocore, F.; Suntharalingham, J. P.; Ogunbiyi, O.; Jones, A.; Moreno, N.; Niola, P.; Brooks, T.; Solanky, N.; Dattani, M. T.; del Valle, I.; Achermann, J. C.

10.1101/2024.03.04.583285 — developmental biology — Posted on 2024-03-04

4714 Increasing the vitamin C transporter SVCT2 in microglia improves synaptic plasticity and restrains memory impairments in Alzheimer's disease models

Portugal, C. C.; Santos, E. C. S.; Pacheco, A. M.; Costa-Pinto, S.; Almeida, T. O.; Tedim-Moreira, J.; Gavin, D.; Canedo, T.; Oliveira, F.; Summavielle, T.; Vaz, S. H.; Socodato, R.; Relvas, J. B.

10.1101/2024.02.29.582679 — neuroscience — Posted on 2024-03-04

4715 Indirect Haptic Disturbances Enhance Motor Variability, with Divergent Effects on Skill Transfer

Arink, W.; Poggensee, K. L.; Beckers, N.; Abbink, D. A.; Marchal-Crespo, L.

10.1101/2024.02.29.582677 — neuroscience — Posted on 2024-03-04

4716 Distinct neural bases of subcomponents of the attentional blink

Halder, S.; Raya, D. V.; Sridharan, D.

10.1101/2024.03.04.583330 — neuroscience — Posted on 2024-03-04

4717 Correlation measures in metagenomic data: the blessing of dimensionality

Fuschi, A.; Merlotti, A.; Tran, D. B.; Nguyen, H.; Weinstock, G.; Remondini, D.

10.1101/2024.02.29.582875 — systems biology — Posted on 2024-03-04

4718 The Early Dodder Gets the Host: Decoding the Coiling Patterns of Cuscuta campestris with Automated Image Processing

Bentelspacher, M.; Amezquita, E. J.; Adhikari, S.; Barros-Rios, J.; Park, S.

10.1101/2024.02.29.582789 — plant biology — Posted on 2024-03-04

4719 Self-Supervised Learning Reveals Clinically Relevant Histomorphological Patterns for Therapeutic Strategies in Colon Cancer

Liu, B.; Polack, M.; Coudray, N.; Quiros, A. C.; Sakellaropoulos, T.; Crobach, A. S. L. P.; van Krieken, J. H. J. M.; Yuan, K.; Tollenaar, R. A. E. M.; Mesker, W. E.; Tsirigos, A.

10.1101/2024.02.26.582106 — bioinformatics — Posted on 2024-03-04

4720 Exploring the Dynamics of Social Interactions During the Juvenile Stage in a Mouse Model of Fragile X Syndrome

Bae, M. Y.; Wang, B.; Abdullah, A.; Ahmed, A.; Ilyas, R.; Rasheva, V.; Murari, K.; Cheng, N.

10.1101/2024.03.03.583140 — animal behavior and cognition — Posted on 2024-03-04

4721 Within-host adaptation of a foliar pathogen, Xanthomonas, on pepper in presence of quantitative resistance and ozone stress

Kaur, A.; Russell, I.; Liu, R.; Holland, A.; Bhandari, R.; Potnis, N.

10.1101/2024.02.29.582737 — evolutionary biology — Posted on 2024-03-04

4722 Strategies for Inducing and Validating Zinc Deficiency and Zinc Repletion

Wenegieme, T.-Y.; Elased, D.; Rockwood, J.; Hasrat, K.; McMichael, K.; Marshall, A.; Neikirk, K.; Kirabo, A.; Elased, K.; Hinton, A.; Williams, C.

10.1101/2024.02.28.582542 — physiology — Posted on 2024-03-04

4723 Identification of bazedoxifene for the treatment of LGMD R2 by high throughput screening.

Bruge, C.; Bourg, N.; PELLIER, E.; Tournois, J.; Polentes, J.; BENABIDES, M.; Grossi, N.; Bigot, A.; Brureau, A.; Richard, I.; Nissan, X.

10.1101/2024.02.28.582550 — pharmacology and toxicology — Posted on 2024-03-04

4724 Tumor-microvessel on-a-chip reveals sequential intravasation cascade of cancer cell clusters

Ikeda, Y.; Suehiro, J.-i.; Oshima, H.; Kok, S. Y.; Takahashi, K.; Sakurai, H.; Watabe, T.; Oshima, M.; Matsunaga, Y. T.

10.1101/2024.02.28.582606 — cancer biology — Posted on 2024-03-04

4725 Assessment of Stiffness-Dependent Autophagosome Formation and Apoptosis in Embryonal Rhabdomyosarcoma Tumor Cells

Sezen, S.; Adiguzel, S.; Zareour, A.; Khosravi, A.; Gordon, J.; Ghavami, S.; Zarrabi, A.

10.1101/2024.03.01.583012 — cancer biology — Posted on 2024-03-04

4726 The transcriptomic landscape of monosomy X (45,X) during early human fetal and placental development

Suntharalingham, J. P.; del Valle, I.; Buonocore, F.; McGlacken-Byrne, S. M.; Brooks, T.; Ogunbiyi, O. K.; Liptrot, D.; Dunton, N.; Madhan, G. K.; Metcalfe, K.; Nel, L.; Marshall, A. R.; Ishida, M.; Sebire, N. J.; Moore, G. E.; Crespo, B.; Solanky, N.; Conway, G. S.; Achermann, J. C.

10.1101/2024.03.01.582942 — genetics — Posted on 2024-03-04

4727 Molecular Signatures of Normal Pressure Hydrocephalus: A Large-scale Proteomic Analysis of Cerebrospinal Fluid

Kamalian, A.; Shirzadeh Barough, S.; Ho, S. G.; Albert, M.; Luciano, M. G.; Yasar, S.; Moghekar, A.

10.1101/2024.03.01.583014 — neuroscience — Posted on 2024-03-04

4728 The TD drive - A parametric, open-source implant for multi-area electrophysiological recordings in behaving and sleeping rats

Schroeder, T.; van der Meij, J.; van Heument, P.; Samanta, A.; Genzel, L.

10.1101/2024.03.02.582871 — neuroscience — Posted on 2024-03-04

4729 MAGPIE: an interactive tool for visualizing and analyzing protein-ligand interactions

Rodriguez, D. C. P.; Weber, K. C.; Sundberg, B.; Glasgow, A.

10.1101/2023.09.04.556273 — biophysics — Posted on 2024-03-04

4730 Expression based polygenic scores - A gene network perspective to capture individual differences in biological processes.

Barth, B.; De Mendonca Filho, E. J.; Mar Arcego, D.; pokhvisneva, I.; Meaney, M. J.; Silveira, P. P.

10.1101/2024.03.01.583008 — bioinformatics — Posted on 2024-03-04

4731 Pan-cancer molecular signatures connecting aspartate transaminase (AST) to cancer prognosis, metabolic and immune signatures

Siwo, G. H.; Singal, A. G.; Waljee, A. K.

10.1101/2024.03.01.582939 — genomics — Posted on 2024-03-04

4732 CAM evolution is associated with gene family expansion in an explosive bromeliad radiation

Groot Crego, C.; Hess, J.; Yardeni, G.; de la Harpe, M.; Priemer, C.; Beclin, F.; Cauz-Santos, L. A.; Saadain, S.; Temsch, E. M.; Weiss-Schneeweiss, H.; Barfuss, M. H. J.; Till, W.; Weckwerth, W.; Heyduk, K.; Lexer, C.; Paun, O.; Leroy, T.

10.1101/2023.02.01.526631 — evolutionary biology — Posted on 2024-03-04

4733 Exploiting mechanisms for hierarchical branching structure of lung airway

Takigawa-Imamura, H.; Fumoto, K.; Takesue, H.; Miura, T.

10.1101/2023.03.23.533381 — developmental biology — Posted on 2024-03-04

4734 Fabrication of elastomeric stencils for patterned stem cell differentiation

Lehr, S.; Merrin, J.; Kulig, M.; Minchington, T.; Kicheva, A.

10.1101/2024.03.01.582929 — developmental biology — Posted on 2024-03-04

4735 Genotypic and phenotypic characterization of a nosocomial outbreak of Candida auris in Spain during five years

Mulet, J. V.; Cancino-Munoz, I. N.; Salvador-Garcia, C.; Tormo-Palop, N.; Guna, R.; Gonzalez-Candelas, F.; Gimeno-Cardona, C.

10.1101/2024.03.01.582904 — microbiology — Posted on 2024-03-04

4736 Decoding host-microbiome interactions through co-expression network analysis within the non-human primate intestine

Uehara, M.; Inoue, T.; Hase, S.; Sasaki, E.; Toyoda, A.; Sakakibara, Y.

10.1101/2023.08.11.552617 — microbiology — Posted on 2024-03-04

4737 Exposure to HIV alters the composition of maternal microchimeric T cells in infants

Armistead, B.; Peters, Q.; Houck, J.; Carlson, M.; Balle, C.; Mulugeta, N.; Gray, C.; Jaspan, H. B.; Harrington, W. E.

10.1101/2024.03.01.583002 — immunology — Posted on 2024-03-04

4738 Inverted encoding of neural responses to audiovisual stimuli reveals super-additive multisensory enhancement

Buhmann, Z.; Robinson, A. K.; Mattingley, J. B.; Rideaux, R.

10.1101/2024.02.15.580589 — neuroscience — Posted on 2024-03-04

4739 Using a Forster-resonance energy transfer (FRET)-based detection system (FedEcs) to monitor nanoparticle cargo delivery to the brain

Khalin, I.; Adarsh, N.; Schifferer, M.; Wehn, A.; Boide-Trujillo, V. J.; Mamrak, U.; Shrouder, J. J.; Misgeld, T. J.; Filser, S.; Klymchenko, A. S.; Plesnila, N.

10.1101/2024.02.28.582471 — neuroscience — Posted on 2024-03-04

4740 Emergence of Emotion Selectivity in A Deep Neural Network Trained to Recognize Visual Objects

Liu, P.; Bo, K.; Ding, M.; Fang, R.

10.1101/2023.04.16.537079 — neuroscience — Posted on 2024-03-04

4741 Hippocampal DNA methylation promotes memory persistence by facilitating systems consolidation and cortical engram stabilisation.

Kupke, J.; Loizou, S.; Bengtson, C. P.; Sticht, C.; Oliveira, A. M. M.

10.1101/2024.02.25.581942 — neuroscience — Posted on 2024-03-04

4742 Prediction of brain age in individuals with and at risk for alcohol use disorder using brain morphological features

Kamarajan, C.; Ardekani, B. A.; Pandey, A. K.; Meyers, J. L.; Chorlian, D. B.; Kinreich, S.; Pandey, G.; Richard, C.; de Viteri, S. S.; Kuang, W.; Porjesz, B.

10.1101/2024.03.01.582844 — neuroscience — Posted on 2024-03-04

4743 A novel cell communication method reveals that grik4 and gabrd may be critical for inducing death in RGNNV-infected grouper.

he, t.; yu, y.

10.1101/2024.02.27.582406 — zoology — Posted on 2024-03-04

4744 Analysis of justification for and gender bias in author order among those contributing equally

Mattoon, E. R.; Miles, M.; Casadevall, A.; Broderick, N. A.

10.1101/2024.03.01.582955 — scientific communication and education — Posted on 2024-03-04

4745 Respiration-Triggered Olfactory Stimulation ReducesObstructive Sleep Apnea Symptoms Severity: A Prospective Pilot Study

Perl, O.; Kemer, L.; Green, A.; Arish, N.; Corcos, Y.; Arzi, A.; Dagan, Y.

10.1101/2023.02.28.530439 — physiology — Posted on 2024-03-04

4746 Generative artificial intelligence performs rudimentary structural biology modelling

Ille, A. M.; Markosian, C.; Burley, S. K.; Mathews, M. B.; Pasqualini, R.; Arap, W.

10.1101/2024.01.10.575113 — bioinformatics — Posted on 2024-03-04

4747 De novo peptide sequencing with InstaNovo: Accurate, database-free peptide identification for large scale proteomics experiments

Eloff, K.; Kalogeropoulos, K.; Morell, O.; Mabona, A.; Berg Jespersen, J.; Williams, W.; van Beljouw, S. P. B.; Skwark, M.; Hougaard Laustsen, A.; Brouns, S. J. J.; Ljungars, A.; Schoof, E. M.; Van Goey, J.; auf dem Keller, U.; Beguir, K.; Lopez Carranza, N.; Jenkins, T. P.

10.1101/2023.08.30.555055 — bioinformatics — Posted on 2024-03-04

4748 Chromosome-level genome assembly of milk thistle (Silybum marianum (L.) Gaertn.)

Kim, K. D.; Shim, J.; Hwang, J.-H.; Kim, D.; El baidouri, M.; Park, S.; Song, J.; Yu, Y.; Lee, K.; Ahn, B.-O.; Hong, S. Y.; Chin, J. H.

10.1101/2024.02.29.582772 — genomics — Posted on 2024-03-04

4749 Influence of environmental variables, small-scale fisheries and vessel traffic on the distribution and behavior of bottlenose dolphins in a tropical lagoon.

Brevet, M.; Jaquemet, S.; Wagner, J.; Kiszka, J.

10.1101/2024.02.29.582495 — ecology — Posted on 2024-03-04

4750 The dual role of a highly structured RNA (the S fragment) in the replication of foot-and-mouth disease virus.

Ward, J. C.; Lasecka-Dykes, L.; Dobson, S. J.; Gold, S.; Kingston, N. J.; Herod, M. R.; King, D. P.; Tuthill, T. J.; Rowlands, D. J.; Stonehouse, N. J.

10.1101/2023.04.26.538422 — molecular biology — Posted on 2024-03-04

4751 Time Cells in the Retrosplenial Cortex.

Subramanian, D. L.; Smith, D. M.

10.1101/2024.03.01.583039 — neuroscience — Posted on 2024-03-04

4752 Neuronal lysosome transfer to oligodendrocyte precursor cells: a novel mechanism of neuron-glia communication and its role in neurodegenerative disease

Fang, L.-P.; Lin, C.-H.; Medlej, Y.; Zhao, R.; Chang, H.-F.; Su, Y.; Zhao, N.; Gobbo, D.; Guo, Q.; Wyatt, A.; Wahl, V.; Boehm, U.; Huang, W.; Lauterbach, M. A.; Yi, C.; Niu, J.; Scheller, A.; Kirchhoff, F.; Bai, X.

10.1101/2024.03.03.583173 — neuroscience — Posted on 2024-03-04

4753 Functional Specialization and Distributed Processing across Marmoset Lateral Prefrontal Subregions

Wong, R. K.; Selvanayagam, J.; Johnston, K. D.; Everling, S.

10.1101/2024.02.29.582669 — neuroscience — Posted on 2024-03-04

4754 A specialized inhibitory function sharpens somatosensory hand representation and enhances the production and perception of fast multifinger movements in pianists

Hirano, M.; Kimoto, Y.; Shiotani, S.; Furuya, S.

10.1101/2024.01.23.576947 — neuroscience — Posted on 2024-03-04

4755 Concurrent behavioral modelling and multimodal neuroimaging reveals how feedback affects decision making in internet gaming disorder

Xinglin, Z.; Sun, Y.; Gao, F.; Hua, L.; Tan, W.; Yuan, Z.

10.1101/2023.10.22.563399 — neuroscience — Posted on 2024-03-04

4756 Dynamics of morphogen source formation in a growing tissue

Ho, R. D. J. G.; Kishi, K.; Majka, M.; Kicheva, A.; Zagorski, M.

10.1101/2024.03.01.582751 — systems biology — Posted on 2024-03-03

4757 Multi-condition and multi-modal temporal profile inference during mouse embryonic development

Zhang, R.; Qiu, C.; Filippova, G.; Li, G.; Shendure, J.; Vert, J.-P.; Deng, X.; Disteche, C. M.; Noble, W. S.

10.1101/2024.03.03.583179 — bioinformatics — Posted on 2024-03-04

4758 Evaluating the representational power of pre-trained DNA language models for regulatory genomics

Tang, Z.; Koo, P. K.

10.1101/2024.02.29.582810 — bioinformatics — Posted on 2024-03-04

4759 A generalised protein identification method for novel and diverse sequencing technologies

Bhandari, B. K.; Goldman, N.

10.1101/2024.02.29.582769 — bioinformatics — Posted on 2024-03-04

4760 Non-linear transcriptional responses to gradual modulation of transcription factor dosage

Domingo, J.; Minaeva, M.; Morris, J. A.; Ziosi, M.; Sanjana, N. E.; Lappalainen, T.

10.1101/2024.03.01.582837 — genomics — Posted on 2024-03-04

4761 Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

Vuchkovska, V.; Marti, T. N.; Cisneros, A.; Saiki, L. M.; Henderson, J. O.

10.1101/2024.02.29.582754 — evolutionary biology — Posted on 2024-03-03

4762 Menopause has not evolved as a general trait in mammals: A response to "Do mammals have menopause?"

Chapman, S. N.; Ellis, S.; Lahdenpera, M.; Croft, D. P.; Lummaa, V.

10.1101/2024.02.29.582687 — evolutionary biology — Posted on 2024-03-03

4763 Error causes a perceived pull to the present in evolutionary rates

O'Meara, B. C.; Beaulieu, J.

10.1101/2024.02.29.582777 — evolutionary biology — Posted on 2024-03-04

4764 The potential of undersown species identity vs. diversity to manage disease in crops

Cappelli, S. L.; Domeignoz Horta, L. A.; Gerin, S.; Heinonsalo, J.; Lohila, A.; Raveala, K.; Schmid, B.; Shrestha, R.; Tiusanen, M. J.; Thitz, P.; Laine, A.-L.

10.1101/2024.02.29.582760 — ecology — Posted on 2024-03-03

4765 Time-course transcriptome data of silk glands in day 0-7 last-instar larvae of Bombyx mori (w1 pnd strain)

Masuoka, Y.; Jouraku, A.; Tsubota, T.; Chiba, H.; Ono, H.; Sezutsu, H.; Bono, H.; Yokoi, K.

10.1101/2024.03.02.582034 — molecular biology — Posted on 2024-03-03

4766 Low protein diet protects liver function upon Salmonella infection by metabolic reprogramming of macrophages

Wojtowicz, E. E.; Hampton, K.; Moreno-Gonzalez, M.; Utting, C. L.; Lan, Y.; Ruiz, P.; Beasy, G.; Bone, C.; Hellmich, C.; Maynard, R.; Acton, L.; Telatin, A.; Kingsley, R. A.; Macaulay, I. C.; Rushworth, S. A.; Beraza, N.

10.1101/2024.03.01.582753 — immunology — Posted on 2024-03-03

4767 Cell-type specific effects of Fusarium mycotoxins on primary neuronal and astroglial cells

Szentgyörgyi, V.; Bencsik, N.; Micska, B.; Ratkai, A.; Schlett, K.; Tarnok, K.

10.1101/2024.02.29.582764 — neuroscience — Posted on 2024-03-03

4768 Direct retino-iridal projections and intrinsic iris contraction mediate the pupillary light reflex in early vertebrates

Jimenez-Lopez, C.; Rivas-Ramirez, P.; Barandela, M.; Nunez-Gonzalez, C.; Megias, M.; Perez-Fernandez, J.

10.1101/2024.02.29.582767 — neuroscience — Posted on 2024-03-03

4769 Sexual dimorphism in the distribution and density of regulatory interneurons in the striatum

Van Zandt, M.; Flanagan, D.; Pittenger, C.

10.1101/2024.02.29.582798 — neuroscience — Posted on 2024-03-04

4770 α7 nicotinic acetylcholine receptors are necessary for basal forebrain activation to increase expression of the nerve growth factor receptor TrkA

Kumro, J.; Tripathi, A.; Terry, A. V.; Pillai, A.; Blake, D. T.

10.1101/2024.03.01.582932 — neuroscience — Posted on 2024-03-04

4771 Self-organization of modular activity in immature cortical networks

Mulholland, H. N.; Kaschube, M.; Smith, G. B.

10.1101/2024.03.02.583133 — neuroscience — Posted on 2024-03-04

4772 Systematics of the fleshy-fruited Sonerileae (Melastomataceae)

Quakenbush, J. P.; Chen, L.; Penneys, D. S.; Barkman, T. J.; Liu, Y.; Yakandawala, D.; Libalah, M. C. V. E.; Kadereit, G.

10.1101/2024.03.03.582138 — plant biology — Posted on 2024-03-03

4773 Trabectedin Enhances Oncolytic Virotherapy by Reducing Barriers to Virus Spread and Cytotoxic Immunity in Preclinical Pediatric Bone Sarcoma

Ringwalt, E. M.; Currier, M. A.; Glaspell, A. M.; Chen, C.-Y.; Cannon, M. V.; Cam, M.; Gross, A. C.; Gust, M.; Wang, P.-Y.; Boon, L.; Biederman, L. E.; Schwarz, E.; Rajappa, P.; Lee, D. A.; Mardis, E. R.; Carson, W. E.; Roberts, R. D.; Cripe, T. P.

10.1101/2024.03.02.582994 — cancer biology — Posted on 2024-03-03

4774 Flexible and high-throughput simultaneous profiling of gene expression and chromatin accessibility in single cells

Soltys, V.; Peters, M.; Su, D.; Kucka, M.; Chan, Y. F.

10.1101/2024.02.26.581705 — genomics — Posted on 2024-03-03

4775 Finding divergent sequences of homomorphic sex chromosomes via diploidized nanopore-based assembly from a single male

Filipovic, I.; Marshall, J. M.; Rasic, G.

10.1101/2024.02.29.582759 — genomics — Posted on 2024-03-03

4776 The Updated Mouse Universal Genotyping Array Bioinformatic Pipeline Improves Genetic QC in Laboratory Mice

Blanchard, M. W.; Sigmon, J. S.; Brennan, J.; Ahulamibe, C.; Allen, M. E.; Baric, R. S.; Bell, T. A.; Farrington, J.; Ciavatta, D.; Cruz Cisneros, M.; Drushal, M.; Ferris, M. T.; Fry, R.; Gaines, C.; Gu, B.; Heise, M. T.; Hodges, R. A.; Kafri, T.; Lynch, R.; Magnuson, T.; Miller, D.; Murphy, C. E. Y.; Nguyen, D. T.; Noll, K. E.; Proulx, M.; Sassetti, C.; Shaw, G. D.; Simon, J. M.; Smith, C.; Styblo, M.; Tarantino, L.; Woo, J.; Pardo-Manuel de Villena, F.

10.1101/2024.02.29.582794 — genetics — Posted on 2024-03-03

4777 The role of many-to-one mapping of vertebral form to function in Psittaciform tripedal locomotion

Stuart, A. R.; Granatosky, M. C.; Felice, R. N.; Marek, R. D.

10.1101/2024.02.29.582755 — evolutionary biology — Posted on 2024-03-03

4778 Inferring stability and persistence in the vaginal microbiome: A stochastic model of ecological dynamics

Ponciano, J. M.; Gomez, J. P.; Ravel, J.; Forney, L. J.

10.1101/2024.03.02.581600 — ecology — Posted on 2024-03-03

4779 Cold stress induces a rapid redistribution of the antagonistic marks H3K4me3 and H3K27me3 in Arabidopsis thaliana

Faivre, L. A. C.; Kinscher, N. F.; Kuhlmann, A. B.; Xu, X.; Kaufmann, K.; Schubert, D.

10.1101/2024.02.29.582735 — plant biology — Posted on 2024-03-03

4780 Grove-level analysis of titer and prevalence of Candidatus Liberibacter asiaticus and Wolbachia in Diaphorina citri, vector of citrus Huanglongbing

Mann, M.; Thompson, L.; Johnson, L.; Heck, M. L.

10.1101/2023.10.04.560920 — plant biology — Posted on 2024-03-03

4781 Beyond Kaftrio: mechanistic insights to maximize N1303K-CFTR rescue

Pranke, I.; Capurro, V.; Chevalier, B.; Pesce, E.; Tomati, V.; Pastorino, C.; Hatton, A.; Urien, S.; Lena, M.; Dreano, E.; Bocciardi, R.; Zara, F.; Pantano, S.; Terlizzi, V.; Lucanto, C.; Costa, S.; Claut, L.; Dacco, V.; Poli, P.; Maschio, M.; Fabrizzi, B.; Caporelli, N.; Cipolli, M.; Volpi, S.; Jung, V.; Roger, K.; Chedevergne, F.; Cosson, L.; Macey, J.; LeBihan, J.; Weiss, L.; Grenet, D.; LeClainche Viala, L.; Douvry, B.; Ravoninjatovo, B.; Audousset, C.; Tatopoulos, A.; Richaud Thiriez, B.; Baravalle, M.; Thouvenin, G.; Labbe, G.; Mittaine, M.; Reix, P.; Durieu, I.; Mankikian, J.; Bui, S.;

10.1101/2024.02.29.582514 — physiology — Posted on 2024-03-03

4782 Comparing cellular response to two radiation treatments based on key features visualization

Arsenteva, P.; Guipaud, O.; Paget, V.; Dos Santos, M.; Tarlet, G.; Milliat, F.; Cardot, H.; Benadjaoud, M. A.

10.1101/2024.02.29.582706 — bioinformatics — Posted on 2024-03-03

4783 scELMo: Embeddings from Language Models are Good Learners for Single-cell Data Analysis

Liu, T.; Chen, T.; Zheng, W.; Luo, X.; Zhao, H.

10.1101/2023.12.07.569910 — bioinformatics — Posted on 2024-03-03

4784 Unveiling the Power of High-Dimensional Cytometry Data with cyCONDOR

Kroeger, C.; Mueller, S.; Leidner, J.; Kroeber, T.; Warnat-Herresthal, S.; Spintge, J. B.; Zajac, T.; Frolov, A.; Carraro, C.; Puccio, S.; Schultze, J. L.; Pecht, T.; Beyer, M. D.; Bonaguro, L.

10.1101/2024.02.29.582727 — bioinformatics — Posted on 2024-03-03

4785 Reduction Midpoint Potential of a Paradigm Light-Oxygen-Voltage Receptor and its Modulation by Methionine Residues

Garcia de Fuentes, A.; Moeglich, A.

10.1101/2024.02.29.582800 — biochemistry — Posted on 2024-03-03

4786 Uncovering the genetic diversity in Aedes aegypti insecticide resistance genes through global comparative genomics

Spadar, A.; Collins, E.; Messenger, L. A.; Clark, T. G.; Campino, S.

10.1101/2024.02.29.582728 — genomics — Posted on 2024-03-03

4787 A binary trait model reveals the fitness effects of HIV-1 escape from T cell responses

Gao, Y.; Barton, J. P.

10.1101/2024.03.03.583183 — evolutionary biology — Posted on 2024-03-03

4788 Essential Function of Transmembrane Transcription Factor MYRF in Promoting Transcription of miRNA lin-4 during C. elegans Development

Xu, Z.; Wang, Z.; Wang, L.; Qi, Y.

10.1101/2023.06.22.546200 — developmental biology — Posted on 2024-03-03

4789 Creation and manipulation of bipartite expression transgenes in C. elegans using phiC31 recombinase

Nonet, M. L.

10.1101/2024.03.01.583017 — molecular biology — Posted on 2024-03-03

4790 The MLL3/TP53/PIK3CA cancer driver mutations promote HIF1alpha-dependent recruitment and differentiation of pro-tumor ICOShiGITRhi Blimp-1+ effector regulatory T cells in breast tumors

Boutet, M.; Nishitani, K.; Erler, P.; Couturier, N.; Zhang, Z.; Barbieux, E.; Guillen, E.; Suzuki, M.; Guo, W.; Lauvau, G.

10.1101/2022.10.02.510540 — immunology — Posted on 2024-03-03

4791 Predicting Attentional Focus: Heartbeat-Evoked Responses and Brain Dynamics During Interoceptive and Exteroceptive Information Processing

Flo, E.; Belloli, L.; Cabana, A.; Ruyan-Belabbas, A.; Jodaitis, L.; Valente, M.; Rohaut, B.; Naccache, L.; Rosanova, M.; Comanducci, A.; Andrillon, T.; Sitt, J.

10.1101/2023.11.03.565584 — neuroscience — Posted on 2024-03-03

4792 The IRE1-bZIP60 branch of Unfolded Protein Response is required for Arabidopsis immune response to B. cinerea

Blanchard, C.; Aime, S.; Ducloy, A.; Hichami, S.; Azzopardi, M.; Cacas, J.-L.; Lamotte, O.

10.1101/2023.10.18.562849 — plant biology — Posted on 2024-03-03

4793 Brassinosteroid and gibberellin signaling are required for Tomato internode elongation in response to low red: far-red light

Li, L.; Helming, T.; Wonder, J.; van Asselt, G.; Pantazopoulou, C. K.; van de Kaa, Y. T. R.; Kohlen, W.; Pierik, R.; Kajala, K.

10.1101/2024.02.29.582690 — plant biology — Posted on 2024-03-03

4794 Pharmacological Characterization of SDX-7320/Evexomostat: a Novel Methionine Aminopeptidase Type 2 Inhibitor with Anti-Tumor and Anti-Metastatic Activity

Cornelius, P.; Mayes, B. A.; Petersen, J. S.; Turnquist, D. J.; Dufour, P. J.; Shanahan, J. M.; Carver, B. J.

10.1101/2024.02.29.582701 — pharmacology and toxicology — Posted on 2024-03-03

4795 Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma

Motahari, Z.; Lepe, J. L.; Bautista, M. R.; Hoerig, C.; Plant-Fox, A. S.; Das, B.; Fowler, C. D.; Magge, S. N.; Bota, D. A.

10.1101/2024.02.29.582709 — cancer biology — Posted on 2024-03-03

4796 CYB561 supports the neuroendocrine phenotype in castration-resistant prostate cancer

Azur, R. A.; Olarte, K. C.; Ybanez, W.; Ocampo, A. M.; Bagamasbad, P. D.

10.1101/2024.02.29.582710 — cancer biology — Posted on 2024-03-03

4797 Exploring Abeta42 Monomer Diffusive Dynamics on Fibril Surfaces through Molecular Simulations

Ma, Y.-W.; Wang, G.-F.; Tsai, M.-Y.

10.1101/2024.02.29.582685 — biophysics — Posted on 2024-03-03

4798 Resolving atomic-level dynamics and interactions of high-molecular weight hyaluronic acid in biomimetic ECM hydrogels by multidimensional solid-state NMR

Rampratap, P.; Lasorsa, A.; Arunachalam, A.; Kamperman, M.; Walvoort, M. T. C.; van der Wel, P. C. A.

10.1101/2024.02.29.582163 — biophysics — Posted on 2024-03-03

4799 Compound-SNE: Comparative alignment of t-SNEs for multiple single-cell omics data visualisation

Cess, C. G.; Haghverdi, L.

10.1101/2024.02.29.582536 — bioinformatics — Posted on 2024-03-03

4800 The influence of scaffold deformation and fluid mechanical stimuli on bone tissue differentiation.

Moliner, L.; Ruiz Wills, C.; Camara, O.; Olivares, A. L.

10.1101/2024.02.29.582717 — bioengineering — Posted on 2024-03-03

4801 Stage-resolved chromatin conformation dynamics during human meiosis

Kaiser, V. B.; Semple, C. A.

10.1101/2024.02.29.582729 — genomics — Posted on 2024-03-03

4802 SMA Type II Skeletal Muscle Treated with Nusinersen shows SMN Restoration but Mitochondrial Deficiency.

Grandi, F. C.; Astord, S.; Gidaja, E.; Pezet, S.; Mazzucchi, S.; Chapart, M.; Vasseur, S.; Mamchaoui, K.; Smeriglio, P.

10.1101/2024.02.29.582680 — genetics — Posted on 2024-03-03

4803 TabHLH27 orchestrates root growth and drought tolerance to enhance water use efficiency in wheat

Wang, D.; Zhang, X.; Cao, Y.; Batool, A.; Xu, Y.; Qiao, Y.; Li, Y.; Wang, H.; Lin, X.; Bie, X.; Zhang, X.; Jing, R.; Dong, B.; Tong, Y.; Teng, W.; Liu, X.; Xiao, J.

10.1101/2024.02.29.582695 — genetics — Posted on 2024-03-03

4804 Decoding the Baltic Sea's Past and Present: A simple Molecular Index for Ecosystem Assessment

Schmidt, A.; Roman, J.; Andren, E.; Kremp, A.; Kaiser, J.; Arz, H. W.; Dellwig, O.; Balint, M.; Epp, L. S.

10.1101/2024.02.29.582456 — ecology — Posted on 2024-03-03

4805 Depletion of essential GroEL protein in Escherichia coli using Clp-Interacting Peptidic Protein Erasers (CLIPPERs)

Izert-Nowakowska, M. A.; Klimecka, M. M.; Antosiewicz, A.; Wroblewski, K.; Bandyra, K. J.; Goral, T. K.; Kmiecik, S.; Serwa, R. A.; Gorna, M. W.

10.1101/2024.02.29.582761 — molecular biology — Posted on 2024-03-03

4806 Parameters that influence bipartite reporter system expression in C. elegans

Knoebel, E.; Brinck, A.; Nonet, M. L.

10.1101/2024.03.01.583016 — molecular biology — Posted on 2024-03-03

4807 Unlocking Herbal Potentials: Novel Shikimate Kinase Inhibitors in the Fight Against Antibiotic Resistance

Nirgudkar, S.; Chai, Y.

10.1101/2024.03.02.583126 — microbiology — Posted on 2024-03-03

4808 Multiple resistance factors collectively promote inoculum-dependent dynamic survival during antimicrobial peptide exposure in Enterobacter cloacae

Murtha, A. N.; Kazi, M. I.; Kim, E.; Rosch, K. M.; Torres, F. V.; Doerr, T.

10.1101/2024.03.03.583169 — microbiology — Posted on 2024-03-03

4809 Yellow Fever Emergence: Role of Heterologous Flavivirus Immunity in Preventing Urban Transmission

Shinde, D. P.; Plante, J. A.; Scharton, D.; Mitchel, B.; Walker, J.; Azar, S. R.; Kroon-Campos, R.; Sacchetto, L. A.; Drumond, B. P.; Vasilakis, N.; Plante, K. S.; Weaver, S. C.

10.1101/2024.03.03.583168 — microbiology — Posted on 2024-03-03

4810 Sequential Transcriptional Programs of Tissue Residency Drive Human Uterine NK Cell Development

Greene, M. E.; Asiimwe, R.; Wright, E.; Bell, M.; Epstein, D.; Yates, S. D.; Knott, B.; Fry, S.; Clevenger, S.; Locke, J.; Little, S. C.; Richter, H.; Freud, A. G.; Porrett, P. M.

10.1101/2024.02.29.582684 — immunology — Posted on 2024-03-03

4811 The Molecular Landscape of Cellular Metal Ion Biology

Aulakh, S. K.; Lemke, O.; Szyrwiel, L.; Kamrad, S.; Chen, Y.; Hartl, J.; Muelleder, M.; Nielsen, J.; Ralser, M.

10.1101/2024.02.29.582718 — systems biology — Posted on 2024-03-03

4812 Single-cell multiomics reveals a gene regulatory circuit promoting leukemia cell differentiation

Tian, X.; Zhang, L.; Tang, Y.; Xiang, G.; Wang, Z.; Zhu, P.; Yu, S.; Jiang, F.; Wang, S.; Wang, J.; Dai, Y.; Zhang, D.; Wang, J.; Liu, H.; Weng, X.; Wang, S.; Tan, Y.; Chen, Z.; Chen, S.; Liu, F.

10.1101/2024.02.29.582681 — cancer biology — Posted on 2024-03-03

4813 SEGUID v2: Extending SEGUID checksums for circular, linear, single- and double-stranded biological sequences

Pereira, H.; Silva, P. C.; Davis, W. M.; Abraham, L.; Babnigg, G.; Bengtsson, H.; Johansson, B.

10.1101/2024.02.28.582384 — bioinformatics — Posted on 2024-03-03

4814 MMCCI: Multimodal Cell-Cell Interaction Integrative Analysis of Single Cell and Spatial Data

Hockey, L.; Mulay, O.; Xiong, Z.; Khosrotehrani, K.; Nefzger, C. M.; Nguyen, Q.

10.1101/2024.02.28.582639 — bioinformatics — Posted on 2024-03-03

4815 Cysteine restriction induces ferroptosis depending on the polyamine biosynthetic pathway in hepatic cancer cells

Tada, K.; Nishizawa, H.; Shima, H.; Muto, A.; Wada, M.; Igarashi, K.

10.1101/2024.02.29.582667 — biochemistry — Posted on 2024-03-03

4816 The widely used cymoxanil fungicide impairs respiration in Saccharomyces cerevisiae via cytochrome c oxidase inhibition

Mendes, F.; Pereira, C.; Vieira, T.; Pinto, M.; Castro, B.; Sousa, S.; Sousa, M. J.; Devin, A.; Chaves, S.

10.1101/2024.02.29.582674 — biochemistry — Posted on 2024-03-03

4817 Testing the mettle of METAL: A comparison of phylogenomic methods using a challenging but well-resolved phylogeny

Braun, E. L.; Oliveros, C. H.; White Carreiro, N. D.; Zhao, M.; Glenn, T. C.; Brumfield, R. T.; Braun, M. J.; Kimball, R. T.; Faircloth, B. C.

10.1101/2024.02.28.582627 — evolutionary biology — Posted on 2024-03-03

4818 Understanding the effects of oxytocin receptor variants on OXT-OXT receptor binding: A mathematical model

Dubey, P.; Fang, Y.; Tukei, K. L.; Kuila, S.; Liu, X.; Sahota, A.; Frolova, A. I.; Reinl, E. L.; Malik, M.; England, S. K.; Imoukhuede, P. I.

10.1101/2024.02.28.582600 — systems biology — Posted on 2024-03-03

4819 The trade-off between grain weight and grain number in wheat is explained by the overlapping of the key phases determining these major yield components

Vicentin, L.; Canales, J.; Calderini, D. F.

10.1101/2024.02.28.582521 — plant biology — Posted on 2024-03-03

4820 HY5 and COP1 function antagonistically in the light-dependent regulation of nicotine biosynthesis in tobacco

Singh, D.; Dwivedi, S.; Singh, N.; Trivedi, P.

10.1101/2024.02.28.582661 — plant biology — Posted on 2024-03-03

4821 Suppressing mortality and curbing cellular damage by targeting VHL

Jiang, W.; Cao, Y.; Xue, Y.; Ji, Y.; Winer, B. Y.; Zhang, M.; Singhal, N. S.; Pierce, J.; Chen, S.; Ma, D. K.

10.1101/2024.02.28.582664 — physiology — Posted on 2024-03-03

4822 The atypical antipsychotic lurasidone positively modulates the gut microbiota in rats: A comparative study to olanzapine

Kamath, S.; Hunter, A.; Collins, K.; Wignall, A.; Joyce, P.

10.1101/2024.02.28.582623 — pharmacology and toxicology — Posted on 2024-03-03

4823 Inkject Printed Graphene Microelectrodes for Real-Time Impedance Spectroscopy of Neural Cells in Organ-on-a Chip

Ouedraogo, L. J. G.; Hashemi, N.

10.1101/2024.02.28.582633 — bioengineering — Posted on 2024-03-03

4824 Loss of factor VIII in zebrafish rebalances antithrombin deficiency but has a limited bleeding diathesis

Richter, C. E.; Raghunath, A.; Griffin, M. S.; Yaman, M.; Arruda, V. R.; Samelson-Jones, B. J.; Shavit, J.

10.1101/2024.02.28.582609 — genetics — Posted on 2024-03-03

4825 In silico identification of putative causal genetic variants

He, Z.; Chu, B.; Yang, J.; Gu, J.; Chen, Z.; Liu, L.; Morrison, T.; Belloy, M. E.; Qi, X.; Hejazi, N.; Mathur, M.; Le Guen, Y.; Tang, H.; Hastie, T.; Ionita-laza, I.; Sabatti, C.; Candes, E.

10.1101/2024.02.28.582621 — genetics — Posted on 2024-03-03

4826 Widespread evolution of poricidal flowers: A striking example of morphological convergence across flowering plants

Russell, A. L.; Zenil-Ferguson, R.; Buchmann, S.; Jolles, D. D.; Kriebel, R.; Vallejo-Marin, M. L.

10.1101/2024.02.28.582636 — evolutionary biology — Posted on 2024-03-03

4827 Choices to landscapes: Mechanisms of animal movement scale to landscape patterns

Rogers, W.; Yanco, S.; Jetz, W.

10.1101/2024.02.28.582548 — ecology — Posted on 2024-03-03

4828 LRRK2 G2019S mutation suppresses differentiation of Th9 and Treg cells via JAK/STAT3

Zheng, N.; Jaffery, R.; Guerrero, A.; Hou, J.; Pan, Y.; Zhou, F.; Chen, S.; Xu, C.; Egan, N. A.; Bohat, R.; Chen, K.; Schwarzschild, M. A.; Chen, X.; Peng, W.

10.1101/2024.02.28.582561 — immunology — Posted on 2024-03-03

4829 Comparison of Alternative pre-mRNA Splicing and Gene Expression Patterns in Midbrain Lineage Cells Carrying Familial Parkinson's Disease Mutations

Lee, Y. J.; Syed, K.; Busquets, O.; Li, H.; Dunnack, J.; Sahagun, A.; Bateup, H.; Soldner, F.; Hockemeyer, D.; Rio, D.

10.1101/2024.02.28.582420 — neuroscience — Posted on 2024-03-03

4830 Effects of noncanonical genomic imprinting in monoaminergic pathways on the regulation of social behaviors

O'Leary, E. M.; Rahman, S. J.; Tamas, A. L.; Huang, T.; Dweydari, M.; Eggleston, R. L.; Meling, D. D.; Bonthuis, P. J.

10.1101/2024.02.28.582619 — neuroscience — Posted on 2024-03-03

4831 Corticothalamic modelling of sleep neurophysiology with applications to mobile EEG

Morshedzadeh, T.; Kadak, K.; Bastiaens, S. P.; Oveisi, M. P.; Momi, D.; Wang, Z.; Harita, S.; Abou Jaude, M.; Aimone, C. A.; Mann, S.; Hill, S. L.; Griffiths, J. D.

10.1101/2024.02.28.582655 — neuroscience — Posted on 2024-03-03

4832 Two-photon imaging of excitatory and inhibitory neural response to infrared neural stimulation

Fu, P.; Liu, Y.; Zhu, L.; Wang, M.; Yu, Y.; Yang, F.; Zhang, W.; Zhang, H.; Shoham, S.; Roe, A. W.; Xi, W.

10.1101/2024.02.28.582632 — neuroscience — Posted on 2024-03-03

4833 Enhanced intracranial aneurysm development in a rat model of polycystic kidney disease.

Cayron, A. F.; Morel, S.; Azam, M.; Haemmerli, J.; Aoki, T.; Bijlenga, P.; Allemann, E.; Kwak, B. R.

10.1101/2024.02.28.582650 — pathology — Posted on 2024-03-03

4834 Direct measurement of RNA Polymerase II hypertranscription in cancer FFPE samples

Henikoff, S.; Henikoff, J. G.; Paranal, R. M.; Greene, J. E.; Russell, Z. R.; Szulzewsky, F.; Kugel, S.; Holland, E. C.; Ahmad, K.

10.1101/2024.02.28.582647 — cancer biology — Posted on 2024-03-03

4835 DeepSP: Deep Learning-Based Spatial Properties to Predict Monoclonal Antibody Stability

Kalejaye, L. A.; Wu, I.-E.; Terry, T.; Lai, P.-K.

10.1101/2024.02.28.582582 — biophysics — Posted on 2024-03-03

4836 Conformational Ensembles Reveal the Origins of Serine Protease Catalysis

Du, S.; Kretsch, R. C.; Parres-Gold, J.; Pieri, E.; Cruzeiro, V. W. D.; Zhu, M.; Pinney, M. M.; Yabukarski, F.; Schwans, J. P.; Martinez, T. J.; Herschlag, D.

10.1101/2024.02.28.582624 — biophysics — Posted on 2024-03-03

4837 DiffGR: Detecting differentially interacting genomic regions from Hi-C contact maps

Liu, H.; Ma, W.

10.1101/2020.08.29.273698 — bioinformatics — Posted on 2024-03-03

4838 Multi-view graph learning for deciphering the dominant cell communication assembly of downstream functional events from single-cell RNA-seq data

Ji, B.-Y.; Wang, X.-Q.; Wang, X.; Xu, L.-W.; Peng, S.-L.

10.1101/2024.02.28.582416 — bioinformatics — Posted on 2024-03-03

4839 DeepKymoTracker: A tool for accurate construction of cell lineage trees for highly motile cells

Fedorchuk, K.; Russell, S. M.; Zibaei, K.; Yassin, M.; Hicks, D. G.

10.1101/2024.02.28.582654 — bioinformatics — Posted on 2024-03-03

4840 Chlomito: a novel tool for precise elimination of organelle genome contamination in nuclear genome assemblies

Song, W.; Li, C.; Lu, Y.; Shen, D.; Jia, Y.; Huo, Y.; Piao, W.; Jin, H.

10.1101/2024.02.28.582616 — bioinformatics — Posted on 2024-03-03

4841 Investigating transcriptional differences in mechanotransductive and ECM related genes in cultured primary corneal keratocytes, fibroblasts and myofibroblasts

Poole, K.; Iyer, K. S.; Schmidtke, D. W.; Petroll, M.; Varner, V. D.

10.1101/2024.02.28.582620 — bioengineering — Posted on 2024-03-03

4842 Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin

Ye, Q.; Henrickson, A.; Demeler, B.; Serrao, V. H.; Davies, P. L.

10.1101/2024.02.28.582628 — biochemistry — Posted on 2024-03-03

4843 Auditory Feature-based Perceptual Distance

Chen, S.; Thielk, M.; Gentner, T. Q.

10.1101/2024.02.28.582631 — animal behavior and cognition — Posted on 2024-03-03

4844 Systems genetics approach uncovers associations between host amylase locus, gut microbiome and metabolic traits in hyperlipidemic mice

Zhang, Q.; Hutchison, E. R.; Pan, C.; Warren, M. F.; Keller, M. P.; Attie, A. D.; Lusis, A. J.; Rey, F. E.

10.1101/2024.02.28.582610 — genetics — Posted on 2024-03-03

4845 Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection

Greene, T. T.; Jo, Y.; Macal, M.; Fang, Z.; Khatri, F. S.; Codrington, A. L.; Kazane, K. R.; Chiale, C.; Akbulut, E.; Swaminathan, S.; Fujita, Y.; Fitzgerald-Bocarsly, P.; Cordes, T.; Metallo, C.; Scott, D. A.; Zuniga, E. I.

10.1101/2024.02.28.582551 — immunology — Posted on 2024-03-03

4846 Kruppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities

Pestal, K.; Slayden, L.; Barton, G.

10.1101/2024.02.28.582578 — immunology — Posted on 2024-03-03

4847 Learning to Choose: Behavioral Dynamics Underlying the Initial Acquisition of Decision Making

White, S. R.; Preston, M. W.; Swanson, K.; Laubach, M.

10.1101/2024.02.28.582581 — neuroscience — Posted on 2024-03-03

4848 Neural coding in gustatory cortex reflects consumption decisions: Evidence from conditioned taste aversion

Raymond, M. A.; Chapman, I. F.; Staszko, S. M.; Fletcher, M. L.; Boughter, J. D.

10.1101/2024.02.28.582584 — neuroscience — Posted on 2024-03-03

4849 Statin-mediated reduction in mitochondrial cholesterol primes an anti-inflammatory response in macrophages by upregulating JMJD3

Saiioum, Z.; Dauner, K.; Li, Y.-f.; Verma, N.; Almendro-Vedia, V.; VALDIVIESO GONZALEZ, D.; Zhang, D. J.; Nakka, K.; McDonald, J.; Sorisky, A.; Song, B.-L.; Lopez Montero, I.; Luo, J.; Dilworth, J.; Zha, X.

10.1101/2023.01.09.523264 — biochemistry — Posted on 2024-03-03

4850 Biotic and abiotic drivers of ecosystem functioning differ between a temperate and a tropical region

van Dijk, L. J. A.; Miraldo, A.; Raharinjanahary, D.; Rajoelison, E. T.; Fisher, B. L.; Goodsell, R. M.; Iwaszkiewicz-Eggebrecht, E.; Ahlen, D.; Högvall, J.; Lundberg, E.; Rova, E.; Łukasik, P.; Ronquist, F.; Roslin, T.; Tack, A. J. M.

10.1101/2024.02.28.582312 — ecology — Posted on 2024-03-03

4851 Protein supersaturation powers innate immune signaling

Rodriguez Gama, A.; Miller, T.; Lange, J. J.; Wu, J.; Song, X.; Venkatesan, S.; Unruh, J.; Bradford, W.; Halfmann, R.

10.1101/2023.03.20.533581 — immunology — Posted on 2024-03-03

4852 MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures

Sit, T. P.; Feord, R. C.; Dunn, A. W.; Chabros, J.; Oluigbo, D.; Smith, H. H.; Burn, L.; Chang, E.; Boschi, A.; Yuan, Y.; Gibbons, G. M.; Khayat-Khoei, M.; De Angelis, F.; Hemberg, E.; Hemberg, M.; Lancaster, M. A.; Lakatos, A.; Eglen, S. J.; Paulsen, O.; Mierau, S. B.

10.1101/2024.02.05.578738 — neuroscience — Posted on 2024-03-03

4853 Network States in the Basolateral Amygdala Predicts Voluntary Alcohol Consumption

DiLeo, A.; Antonoudiou, P.; Blandino, K.; Conlin, E.; Melon, L.; Maguire, J.

10.1101/2023.06.21.545962 — neuroscience — Posted on 2024-03-03

4854 Stand age diversity and climate change affect forests' resilience and stability, although unevenly

Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Cescatti, A.; Colantoni, A.; Chirici, G.; Collalti, A.

10.1101/2023.07.12.548709 — plant biology — Posted on 2024-03-03

4855 Structural architecture of amyloid-β oligomers, curvilinear protofibrils and annular assemblies, imaged by cryo-EM and cryo-ET

Liang, R.; Torres-Flores, A. P.; Qi, S.; Khursheed, A.; Tian, Y.; Szwedziak, P.; Baker, M. D.; Volkov, V. A.; Darbari, V. C.; Viles, J. H.

10.1101/2024.03.01.582902 — biophysics — Posted on 2024-03-03

4856 Role of protein-protein interactions on model chromatin organization

Swain, P.; Choubey, S.; Vemparala, S.

10.1101/2024.03.03.583162 — biophysics — Posted on 2024-03-03

4857 Phase Separation and Aggregation of α-Synuclein Diverge at Different Salt Conditions

Sternke-Hoffmann, R.; Sun, X.; Menzel, A.; Pinto, M. d. S.; Venclovaite, U.; Woerdehoff, M. M.; Hoyer, W.; Zheng, W.; Luo, J.

10.1101/2024.03.01.582895 — biophysics — Posted on 2024-03-03

4858 LogoMotif: a comprehensive database of transcription factor binding site profiles in Actinobacteria

Augustijn, H. E.; Karapliafis, D.; Joosten, K.; Rigali, S.; van Wezel, G. P.; Medema, M. H.

10.1101/2024.02.28.582527 — bioinformatics — Posted on 2024-03-03

4859 Structural Requirements for Activity of Mind bomb1 in Notch Signaling

Cao, R.; Gozlan, O.; Tveriakhina, L.; Zhou, H.; Jiang, H.; Cole, P. A.; Aster, J. C.; Sprinzak, D.; Blacklow, S. C.

10.1101/2024.03.01.582834 — biochemistry — Posted on 2024-03-03

4860 Structure-guided aminoacylation and assembly of chimeric RNAs

Radakovic, A.; Lewicka, A.; Todisco, M.; Aitken, H. R. M.; Weiss, Z.; Kim, S.; Bannan, A.; Piccirilli, J. A.; Szostak, J. W.

10.1101/2024.03.02.583109 — biochemistry — Posted on 2024-03-03

4861 Natural Induction: Spontaneous adaptive organisation without natural selection

Buckley, C. L.; Lewens, T.; Levin, M.; Millidge, B.; Tschantz, A.; Watson, R. A.

10.1101/2024.02.28.582499 — evolutionary biology — Posted on 2024-03-03

4862 Cellular mechanotransduction of human osteoblasts in microgravity

Wubshet, N. H.; Cai, G.; Chen, S. J.; Sullivan, M.; Reeves, M.; Mays, D.; Harrison, M.; Varnado, P.; Yang, B. A.; Arreguin-Martinez, E.; Qu, Y.; Lin, S.-S.; Duran, P.; Aguilar, C. A.; Giza, S.; Clements, T.; Liu, A. P.

10.1101/2024.03.03.583164 — cell biology — Posted on 2024-03-03

4863 Breaking the Burst: Unveiling Mechanisms Behind Fragmented Network Bursts in Patient-derived Neurons

Doorn, N.; Voogd, E. J. H. F.; Levers, M. R.; van Putten, M. J. A. M.; Frega, M.

10.1101/2024.02.28.582501 — neuroscience — Posted on 2024-03-03

4864 Quantitative profiling of human translation initiation reveals regulatory elements that potently affect endogenous and therapeutically modified mRNAs

Lewis, C. J. T.; Xie, L.; Bhandarkar, S.; Jin, D.; Abdallah, K. S.; Draycott, A. S.; Chen, Y.; Thoreen, C. C.; Gilbert, W. V.

10.1101/2024.02.28.582532 — systems biology — Posted on 2024-03-03

4865 Voluntary co-contraction of ankle muscles alters motor unit discharge characteristics and reduces estimates of persistent inward currents

Gomes, M. M.; Jenz, S. T.; Beauchamp, J. A.; Negro, F.; Heckman, C. J.; Pearcey, G. E. P.

10.1101/2024.02.28.582534 — physiology — Posted on 2024-03-03

4866 Exploring the potential of Celtis aetnensis compounds through Molecular Docking for Hepatocellular carcinoma.

Nadiger, K. K.; K, R.; Tamiraikani, T.

10.1101/2024.02.28.582503 — cancer biology — Posted on 2024-03-03

4867 A Root Mean Square Deviation Estimation Algorithm (REA) and its use for improved RNA Structure Prediction

Kalampaliki, A.; Dimopoulos, A. C.; Reczko, M.

10.1101/2024.02.28.582508 — bioinformatics — Posted on 2024-03-03

4868 Molecular mechanism of Mad2 conformational conversion promoted by the Mad2-interaction motif of Cdc20

Yu, C. W. H.; Fischer, E. S.; Greener, J. G.; Yang, J.; Zhang, Z.; Freund, S. M. V.; Barford, D.

10.1101/2024.03.03.583158 — biochemistry — Posted on 2024-03-03

4869 Estimation of the Achilles tendon twist in vivo by individual triceps surae muscle stimulation

Lecompte, L.; Crouzier, M.; Baudry, S.; Vanwanseele, B.

10.1101/2024.02.28.582458 — physiology — Posted on 2024-03-03

4870 Ultrasonic Cigarettes: Chemicals and Cytotoxicity are Similar to Heated-Coil Pod-Style Electronic Cigarettes

Omaiye, E. E.; Luo, W.; McWhirter, K. J.; Pankow, J. F.; Talbot, P.

10.1101/2024.02.28.582598 — pharmacology and toxicology — Posted on 2024-03-03

4871 Metastable condensates suppress conversion to amyloid fibrils

Das, T.; Zaidi, F.; Farag, M.; Ruff, K. M.; Messing, J.; Taylor, J. P.; Pappu, R. V.; Mittag, T.

10.1101/2024.02.28.582569 — biophysics — Posted on 2024-03-03

4872 Probing Phosphorylation-Induced Vibrational Couplings in CFTR by 2D IR Spectra Simulations

Zhu, J.; Chen, T.; Zhao, Y.; Ji, G.

10.1101/2024.02.27.582059 — bioinformatics — Posted on 2024-03-03

4873 Geny: A Genotyping Tool for Allelic Decomposition of Killer Cell Immunoglobulin-Like Receptor Genes

Zhou, Q.; Ghezelji, M.; Hari, A.; Ford, M. K. B.; Holley, C.; COVNET Consortium, ; Mirabello, L.; Chanock, S.; Sahinalp, C.; Numanagic, I.

10.1101/2024.02.27.582413 — bioinformatics — Posted on 2024-03-03

4874 MAssively-Parallel Flow cytometry Xplorer (MAPFX): A Toolbox for Analysing Data from the Massively-Parallel Cytometry Experiments

Liao, H.-C.; Speed, T. P.; McCarthy, D. J.; Salim, A.

10.1101/2024.02.28.582452 — bioinformatics — Posted on 2024-03-03

4875 Characterization and Organization of Telomeric-Linked Helicase (TLH) Gene Families in Fusarium oxysporum

Salimi, S.; Abdi, F.; Rahnama, M.

10.1101/2024.02.27.582403 — bioinformatics — Posted on 2024-03-03

4876 iSORT: An Integrative Method for Reconstructing Spatial Organization of Cells using Transfer Learning

Tan, Y.; Wang, A.; Lin, W.; Yan, Y.; Shi, J.

10.1101/2024.02.28.582493 — bioinformatics — Posted on 2024-03-03

4877 Open Iris - An Open Source Framework for Video-Based Eye-Tracking Research and Development

Sadeghi, R.; Ressmeyer, R.; Yates, J.; Otero-Millan, J.

10.1101/2024.02.27.582401 — bioengineering — Posted on 2024-03-03

4878 Changes in Walking Function and Neural Control following Pelvic Cancer Surgery with Reconstruction

Li, G.; Ao, D.; Vega, M. M.; Zandiyeh, P.; Chang, S.-H.; Penny, A. N.; Lewis, V. O.; Fregly, B. J.

10.1101/2024.02.27.582423 — bioengineering — Posted on 2024-03-03

4879 The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin resistant Staphylococcus aureus

Nielsen, T. K.; Petersen, I. B.; Xu, L.; Barbuti, M. D.; Mebus, V. H.; Justh, A.; Alqarzaee, A. A.; Jacques, N.; Oury, C.; Thomas, V. C.; Kjos, M.; Henriksen, C.; Frees, D.

10.1101/2024.03.01.582999 — microbiology — Posted on 2024-03-03

4880 The aging-induced long non-coding RNA MIRIAL controls endothelial cell and mitochondrial function

10.1101/2024.02.28.582649 — cell biology — Posted on 2024-03-03

4881 Early-stage lung adenocarcinoma is driven by an injury-associated, plastic cell state dependent on a KRAS-ITGA3-SRC axis

Moye, A. L.; Dost, A. F. M.; Ietswaart, R.; Sengupta, S.; Ya, V.; Aluya, C.; Fahey, C. G.; Louie, S. M.; Paschini, M.; Kim, C. F.

10.1101/2024.02.27.582165 — cancer biology — Posted on 2024-03-03

4882 Dark-based Optical Sectioning assists Background Removal in Fluorescence Microscopy

Cao, R.; Li, Y.; Wang, W.; Zhang, G.; Wang, G.; Sun, Y.; Renc, W.; Sun, J.; Hou, Y.; Xu, X.; Hu, J.; Lu, Y.; Li, C.; Wu, J.; Li, M.; Qu, J.; Xi, P.

10.1101/2024.03.02.578598 — bioinformatics — Posted on 2024-03-03

4883 Introducing ARTiMiS: A low-cost flow imaging microscope for phytoplankton monitoring in engineered and natural environments

Gincley, B.; Khan, F.; Hartnett, E.; Fisher, A.; Pinto, A. J.

10.1101/2024.02.27.582145 — bioengineering — Posted on 2024-03-03

4884 Identification of an evolutionary conserved binding motif responsible for the recruitment of NMD factors to the UPF1 helicase

Barbarin-Bocahu, I.; Ulryck, N.; Rigobert, A.; Ruiz Gutierrez, N.; Decourty, L.; Raji, M.; Garkhal, B.; Le Hir, H.; Saveanu, C.; Graille, M.

10.1101/2024.02.27.582253 — biochemistry — Posted on 2024-03-03

4885 On the Evolution of Chromosomal Regions with High Gene Strand Bias in Bacteria

Tomasch, J.; Kopejtka, K.; Shivaramu, S.; Mujakic, I.; Koblizek, M.

10.1101/2024.02.28.582576 — evolutionary biology — Posted on 2024-03-03

4886 Evolution Under Thermal Stress Affects Escherichia colis Resistance to Antibiotics

Bullivant, A.; Lozano-Huntelman, N.; Tabibian, K.; Leung, V.; Armstrong, D.; Dudley, H.; Savage, V. M.; Rodriguez-Verdugo, A.; Yeh, P.

10.1101/2024.02.27.582334 — evolutionary biology — Posted on 2024-03-03

4887 The transcriptional regulator Lrp activates the expression of genes involved in tilivalline enterotoxin biosynthesis in Klebsiella oxytoca

De la Cruz, M. A.; Valdez-Salazar, H. A.; Robles-Leyva, N.; Siqueiros-Cendon, T.; Rascon-Cruz, Q.; Rodriguez-Valverde, D.; Leon-Montes, N.; Soria-Bustos, J.; Rosales-Reyes, R.; Cedillo, M. L.; Yanez-Santos, J. A.; Ibarra, J. A.; Torres, J.; Giron, J. A.; Fox, J. G.; Ares, M. A.

10.1101/2024.02.29.582825 — molecular biology — Posted on 2024-03-03

4888 The need for high-resolution gut microbiome characterization to design efficient strategies for sustainable aquaculture production

Gupta, S.; de Leon, A. V.-P.; Kodama, M.; Hötzinger, M.; Clausen, C. G.; Pless, L.; Verissimo, A.; Stengel, B.; Calabuig, V.; Kvingedal, R.; Skugor, S.; Westereng, B.; Harvey, T. N.; Nordborg, A.; Bertilsson, S.; Limborg, M. T.; Morkore, T.; Sandve, S. R.; Pope, P. B.; Hvidsten, T. R.; La Rosa, S. L.

10.1101/2024.02.29.582783 — microbiology — Posted on 2024-03-03

4889 Stand age diversity and climate change affects forests' resilience and stability, although unevenly

Vangi, E.; Dalmonech, D.; Cioccolo, E.; Marano, G.; Bianchini, L.; Puchi, P.; Grieco, E.; Cescatti, A.; Colantoni, A.; Chirici, G.; Collalti, A.

10.1101/2023.07.12.548709 — plant biology — Posted on 2024-03-03

4890 Joint cell type identification in spatial transcriptomics and single-cell RNA sequencing data

Geras, A.; Domzał, K.; Szczurek, E.

10.1101/2023.05.29.542559 — bioinformatics — Posted on 2024-03-03

4891 Genotypic-phenotypic landscape computation based on first principle and deep learning

Liu, Y.; Luo, Y.; Lu, X.; Gao, H.; He, R.; Zhang, X.; Zhang, X.; Li, Y.

10.1101/2023.02.09.527693 — evolutionary biology — Posted on 2024-03-03

4892 Interpretable and explainable predictive machine learning models for data-driven protein engineering

Medina-Ortiz, D.; Khalifeh, A.; Anvari-Kazemabad, H.; D. Davari, M.

10.1101/2024.02.18.580860 — bioinformatics — Posted on 2024-03-03

4893 Population estimates of shorebirds on the Atlantic Coast of southern South America generated from large-scale, simultaneous, volunteer-led surveys

Faria, F.; Aldabe, J.; Almeida, J.; Bonanno, J.; Bugoni, L.; Clay, R.; Garcia-Walther, J.; Gonzalez, A.; Lesterhuis, A.; Nunes, G.; Senner, N.

10.1101/2024.02.26.582090 — ecology — Posted on 2024-03-03

4894 Mycobacterium tuberculosis infection associated immune perturbations correlate with antiretroviral immunity

Tepekule Mueller, B.; Joerimann, L.; Schenkel, C. D.; Opitz, L.; Tschumi, J.; Wolfensberger, R.; Neumann, K.; Kusejko, K.; Zeeb, M.; Boeck, L.; Kaelin, M.; Notter, J.; Furrer, H.; Hoffmann, M.; Hirsch, H. H.; Calmy, A.; Cavassini, M.; Labhardt, N. D.; Bernasconi, E.; Metzner, K. J.; Braun, D. L.; Guenthard, H. F.; Kouyos, R. D.; Duffy, F.; Nemeth, J.; the Swiss HIV Cohort Study,

10.1101/2023.07.14.548872 — immunology — Posted on 2024-03-03

4895 Neurons in the ventral striatopallidal complex modulate lateral hypothalamic orexin/hypocretin neuron activity: Implications for reward-seeking

Mitchell, C. S.; Mohammadkhani, A.; Manning, E. E.; Campbell, E. J.; Fisher, S. D.; Yeoh, J. W.; Pearl, A. J.; Iredale, J. A.; Burton, N. J.; Qiao, M.; Bains, J. S.; McNally, G. P.; Andrews, Z. A.; Graham, B. A.; Scammel, T. E.; Lowell, B. B.; Kong, D.; Borgland, S. L.; Dayas, C. V.

10.1101/2020.03.05.979468 — neuroscience — Posted on 2024-03-03

4896 Comparative single-cell transcriptomic analysis reveals key differentiation drivers and potential origin of vertebrate retina

Zeng, X.; Gyoja, F.; Cui, Y.; Loza, M.; Kusakabe, T. G.; Nakai, K.

10.1101/2023.12.03.569795 — bioinformatics — Posted on 2024-03-03

4897 Structure and RNA-binding of the helically extended Roquin CCCH-type zinc finger

Tants, J.-N.; Oberstrass, L.; Weigand, J. E.; Schlundt, A.

10.1101/2024.03.01.582905 — biochemistry — Posted on 2024-03-03

4898 Structural insights into sphingosine 1-phosphate receptor 4 activation

Gao, W.; Gan, S.; Zhang, M.; Inoue, A.; Xie, M.; He, H.; Zhu, H.; Guo, S.; Qiu, C.; Chang, D.; Yu, J.; Deng, Z.; Ye, F.; Li, S.; Zhang, J.; Zhao, Z.; Xue, M.; Ofosuhene, B.; Xu, Y.; Lin, H.; Qian, X.; Zhu, L.; Du, Y.; Li, H.

10.1101/2024.03.02.583092 — biochemistry — Posted on 2024-03-03

4899 Arid5a uses disordered extensions of its core ARID domain for distinct DNA- and RNA-recognition and gene regulation

von Ehr, J.; Oberstrass, L.; Yazgan, E.; Schnaubelt, L. I.; Bluemel, N.; McNicoll, F.; Weigand, J. E.; Zarnack, K.; Mueller-McNicoll, M.; Korn, S. M.; Schlundt, A.

10.1101/2024.02.29.582703 — biochemistry — Posted on 2024-03-03

4900 Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically

Nandwani, N.; Bhowmik, D.; Childers, M. C.; Goluguri, R. R.; Dawood, A.; Regnier, M.; Spudich, J. A.; Ruppel, K. M.

10.1101/2024.02.29.582851 — biochemistry — Posted on 2024-03-03

4901 Nephronophthisis-associated FBW7 mediates cyst-dependent decline of renal function in ADPKD

Patel, M. M.; GERAKOPOULOS, V.; PETSOUKI, E.; Zimmerman, K. A.; Tsiokas, L.

10.1101/2024.02.29.582788 — genetics — Posted on 2024-03-03

4902 Spatial structure imposes sex-specific costs but does not reduce interlocus sexual conflict

Halder, S.; Kar, S.; Sethi, S.; Tewari, S.; Verma, T.; Nandy, B.

10.1101/2022.10.29.514349 — evolutionary biology — Posted on 2024-03-03

4903 Comparison of CcrM-dependent methylation in Caulobacter crescentus and Brucella abortus by nanopore sequencing

Campbell, M.; Barton, I. S.; Roop, R. M.; Chien, P.

10.1101/2024.03.01.583015 — microbiology — Posted on 2024-03-03

4904 A novel ClpC adaptor protein that functions in the developing Bacillus subtilis spore

Massoni, S. C.; Evans, N.; Hantke, I.; Fenton, C.; Torpey, J. H.; Collins, K. M.; Krysztofinska, E. M.; Muench, J. H.; Thapaliya, A.; Martinez-Lumbreras, S.; Martin, S. H.; Prior, C. B.; Turgay, K.; Isaacson, R. L.; Camp, A. H.

10.1101/2024.03.02.583065 — microbiology — Posted on 2024-03-03

4905 Contribution of the Type 6 Secretion System to Apoptosis and Macrophage Polarization During Burkholderia pseudomallei Infection

Stockton, J. L.; Khakhum, N.; Torres, A. G.

10.1101/2024.03.01.583019 — microbiology — Posted on 2024-03-03

4906 Photosymbiont density is correlated with constitutive and induced immunity in the facultatively symbiotic coral, Astrangia poculata

Changsut, I. V.; Borbee, E. M.; Womack, H. R.; Schickle, A.; Sharp, K. H.; Fuess, L. E.

10.1101/2024.02.28.582547 — immunology — Posted on 2024-03-03

4907 Same principle, but different computations in representing time and space

Sima, S.; Sanayei, M.

10.1101/2023.11.05.565686 — neuroscience — Posted on 2024-03-03

4908 Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer

He, T.; Cheng, C.; Qiao, Y.; Cho, H.; Young, E.; Mannan, R.; Mahapatra, S.; Miner, S. J.; Zheng, Y.; Kim, N.; Zeng, V. Z.; Wisniewski, J. P.; Hou, S.; Jackson, B.; Cao, X.; Su, F.; Wang, R.; Chang, Y.; Kuila, B.; Mukherjee, S.; Dukare, S.; Aithal, K. B.; D.S., S.; Abbineni, C.; Lyssiotis, C. A.; Parolia, A.; Xiao, L.; Chinnaiyan, A. M.

10.1101/2024.02.29.582768 — cancer biology — Posted on 2024-03-03

4909 Synthesis of versatile neuromodulatory molecules by a gut microbial glutamate decarboxylase

Shah, D. D.; Dadi, P.; Pauling, C. W.; Shrivastava, A.

10.1101/2024.03.02.583032 — biochemistry — Posted on 2024-03-02

4910 EXCRETE enables deep proteomics of the cyanobacterial extracellular environment

Russo, D. A.; Oliinyk, D.; Pohnert, G.; Meier, F.; Zedler, J. A. Z.

10.1101/2024.03.01.582910 — biochemistry — Posted on 2024-03-03

4911 RNA G-quadruplexes and calcium ions synergistically induce Tau phase transition in vitro

Yabuki, Y.; Matsuo, K.; Komiya, G.; Kudo, K.; Hori, K.; Ikenoshita, S.; Kawata, Y.; Mizobata, T.; Shioda, N.

10.1101/2024.03.01.582861 — biochemistry — Posted on 2024-03-03

4912 Evaluation of Peregrinus maidis transformer-2 as a target for CRISPR-based control

Wang, Y.-H.; Rivera, D. E.; Klobasa, W.; Lorenzen, M.

10.1101/2024.03.01.582949 — genetics — Posted on 2024-03-03

4913 Aroma compounds profile is affected by the initial yeast ratio in wort co-fermentations

Aguiar-Cervera, J.; Visinoni, F.; Zhang, P.; Hollywood, K.; Vrhovsek, U.; Severn, O.; Delneri, D.

10.1101/2024.03.01.583027 — microbiology — Posted on 2024-03-02

4914 Toxic eburicol accumulation drives the antifungal activity of azoles against Aspergillus fumigatus

Elsaman, H.; Golubtsov, E.; Brazil, S.; Ng, N.; Klugherz, I.; Dichtl, K.; Mueller, C.; Wagener, J.

10.1101/2024.03.02.582832 — microbiology — Posted on 2024-03-02

4915 Investigation of expression of genes encoding glycogen degrading enzymes in Gardnerella swidsinskii and identification of reference genes for quantitative real-time PCR

Kim, A.; Fernando, C.; Kularatne, D.; Hill, J. E.

10.1101/2024.03.02.583113 — microbiology — Posted on 2024-03-02

4916 Coxiella burnetii-containing vacuoles interact with host recycling-endosomal proteins Rab11a and Rab35 for vacuolar expansion

Hall, B. A.; Senior, K. E.; Ocampo, N. T.; Samanta, D.

10.1101/2024.03.01.582943 — microbiology — Posted on 2024-03-03

4917 The fork restart factor PHF6 interacts with RRM2 and binds to H3K56ac marked nascent DNA

Depestel, L.; Bekaert, S.-L.; Sanders, E.; Van Damme, C.; Eggermont, A.; Loontiens, S.; Tilleman, L.; Van Nieuwerburgh, F.; Delhaye, L.; Van Vlierberghe, P.; Eyckerman, S.; Speleman, F.; Durinck, K.

10.1101/2023.03.08.531704 — cancer biology — Posted on 2024-03-02

4918 Unraveling MLL1-fusion Leukemia: Epigenetic Revelations from an iPS Cell Point Mutation

Kobrossy, L.; Xu, W.; Zhang, C.; Feng, W.; Turner, C. E.; Cosgrove, M. S.

10.1101/2022.12.16.520790 — cancer biology — Posted on 2024-03-02

4919 Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria

Sastre-Dominguez, J.; DelaFuente, J.; Toribio-Celestino, L.; Herencias, C.; Herrador-Gomez, P.; Costas, C.; Hernandez-Garcia, M.; Canton, R.; Rodriguez-Beltran, J.; Santos-Lopez, A.; San Millan, A.

10.1101/2024.03.01.582297 — microbiology — Posted on 2024-03-02

4920 Biochemical-free enrichment or depletion of RNA classes in real-time during direct RNA sequencing with RISER

Sneddon, A.; Ravindran, A.; Shanmuganandam, S.; Kanchi, M.; Hein, N.; Jiang, S.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.11.29.518281 — bioinformatics — Posted on 2024-03-02

4921 Prediction of m6A and m5C at single-molecule resolution reveals a cooccurrence of RNA modifications across the transcriptome

Acera Mateos, P.; Sethi, A. J.; Ravindran, A.; Srivastava, A.; Woodward, K.; Mahmud, S.; Kanchi, M.; Guarnacci, M.; Xu, J.; Yuen, Z. W.-S.; Zhou, Y.; Sneddon, A.; Hamilton, W.; Gao, J.; Starrs, L. M.; Hayashi, R.; Wickramasinghe, V. O.; Zarnack, K.; Preiss, T.; Burgio, G.; Dehorter, N.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.03.14.484124 — bioinformatics — Posted on 2024-03-02

4922 O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis

Masclef, L.; Ahmed, O.; Iannantuono, N.; Gagnon, J.; Gushul-Leclaire, M.; Boulay, k.; Estavoyer, B.; Echbicheb, M.; Poy, M.; Ali Boubacar, K.; Boubekeur, A.; Menggad, S.; Schcolnik-Cabrera, A.; Aurelio, B.; Bonneil, E.; Thibault, P.; Hulea, L.; Tanaka, Y.; Mallette, F. A.; Drouin, J.; Affar, E. B.

10.1101/2024.03.01.582838 — molecular biology — Posted on 2024-03-02

4923 Ultrastructural analysis reveals mitochondrial placement independent of synapse placement in fine caliber C. elegans neurons

Riboul, D. V.; Crill, S.; Oliva, C. D.; Restifo, M. G.; Joseph, R.; Joseph, K.; Nguyen, K. C.; Hall, D. H.; Fily, Y.; Macleod, G. T.

10.1101/2023.05.30.542959 — neuroscience — Posted on 2024-03-02

4924 Patterns of Intra-Clustering Analysis Reveal Hidden Oncogenic Relations

Choudalakis, S.; Kastis, G.; Dikaios, N.

10.1101/2024.02.26.582027 — bioinformatics — Posted on 2024-03-02

4925 A Comprehensive Targeted Panel of 295 Genes: Unveiling Key Disease Initiating and Transformative Biomarkers in MultipleMyeloma

Ruhela, V.; Oberoi, R.; Gupta, R.; Gupta, A.

10.1101/2023.10.28.564536 — bioinformatics — Posted on 2024-03-02

4926 Model-Based Estimates for Operant Selection

Borgstede, M.; Anselme, P.

10.1101/2022.07.22.501082 — animal behavior and cognition — Posted on 2024-03-02

4927 Rapid life-history evolution reinforces competitive asymmetry between invasive and resident species

Chapuis, E.; Jarne, P.; David, P.

10.1101/2023.10.25.563987 — evolutionary biology — Posted on 2024-03-02

4928 Birds and mammals have natural selection regulated population dynamics

Witting, L.

10.1101/2021.11.27.470201 — ecology — Posted on 2024-03-02

4929 Protein Kinase A is Functional Component of Focal Adhesions

Kang, M.; Senatore, A. J.; Naughton, H.; McTigue, M.; Beltman, R. J.; Herppich, A. A.; Pflum, M. K. H.; Howe, A. K.

10.1101/2023.08.18.553932 — cell biology — Posted on 2024-03-02

4930 Skeletal muscle effects of antisense oligonucleotides targeting glycogen synthase 1 in a mouse model of Pompe disease

Weiss, L.; Carrer, M.; Shmara, A.; Cheng, C.; Yin, H.; Ta, L.; Boock, V.; Fazeli, Y.; Chang, M.; Paguio, M.; Lee, J.; Yu, H.; Martin, A.; Raben, N.; Weiss, J.; Grossman, T.; Jafar-nejad, P.; Kimonis, V.

10.1101/2024.02.22.580414 — molecular biology — Posted on 2024-03-02

4931 Genomic deletion of Bcl6 differentially affects conventional dendritic cell subsets and compromises Tfh/Tfr/Th17 cell responses

Xiao, H.; Ulmert, I.; Bach, L.; Huber, J.; Narasimhan, H.; Kurochkin, I.; Chang, Y.; Holst, S.; Moerbe, U.; Zhang, L.; Schlitzer, A.; Pereira, F.; Schraml, B.; Baumjohann, D.; Lahl, K.

10.1101/2022.08.10.503322 — immunology — Posted on 2024-03-02

4932 Asparagine availability controls B cell homeostasis

Yazicioglu, Y. F.; Marin, E.; Bentkowska, K.; Andrew, H.; Mitchell, R.; Wong, Z. Y.; Fergusson, J.; Johnstone, J. C.; Ali, M.; Kronsteiner, B.; Coles, M.; Buckley, C.; Dunachie, S.; Clarke, A.

10.1101/2023.04.03.535433 — immunology — Posted on 2024-03-02

4933 Where top-down meets bottom-up: Cell-type specific connectivity map of the whisker system

Rault, N.; Bergmans, T.; Delfstra, N.; Kleijnen, B. J.; Zeldenrust, F.; Celikel, T.

10.1101/2023.07.31.551377 — neuroscience — Posted on 2024-03-02

4934 Skin keratinocyte-derived SIRT1 and BDNF modulate mechanical allodynia in mouse models of diabetic neuropathy

O'Brien, J.; Niehaus, P.; Chang, K.; Remark, J.; Barrett, J.; Dasgupta, A.; Adenegan, M.; Salimian, M.; Kevas, Y.; Chandrasekeran, K.; Kristian, T.; Chellappan, R.; Rubin, S.; Kiemen, A.; Lu, C. P.-J.; Russell, J.; Ho, C.-Y.

10.1101/2023.01.24.523981 — neuroscience — Posted on 2024-03-02

4935 Automated model discovery for human cardiac tissue: Discovering the best model and parameters

Martonova, D.; Peirlinck, M.; Linka, K.; Holzapfel, G. A.; Leyendecker, S.; Kuhl, E.

10.1101/2024.02.27.582427 — bioengineering — Posted on 2024-03-02

4936 Optically active, paper-based scaffolds for 3D cardiac tissue engineering

Guo, F.; Jooken, S.; Ahmad, A.; Yu, W.; Deschaume, O.; Thielemans, W.; Bartic, C.

10.1101/2024.03.01.582954 — bioengineering — Posted on 2024-03-02

4937 Latest RNA and DNA nanopore sequencing allows for rapid avian influenza profiling

Perlas, A.; Reska, T.; CROVILLE, G.; Tarres-Freixas, F.; Guerin, J.-L.; Majo, N.; Urban, L.

10.1101/2024.02.28.582540 — genomics — Posted on 2024-03-02

4938 Light-microscopy based dense connectomic reconstruction of mammalian brain tissue

Tavakoli, M. R.; Lyudchik, J.; Januszewski, M.; Vistunou, V.; Agudelo, N.; Vorlaufer, J.; Sommer, C.; Kreuzinger, C.; Oliveira, B.; Cenameri, A.; Novarino, G.; Jain, V.; Danzl, J. G.

10.1101/2024.03.01.582884 — neuroscience — Posted on 2024-03-02

4939 Multiplex single-cell analysis of serotonergic neuron function in planarians reveals widespread effects in diverse cell types

Emili, E.; Rodriguez-Fernandez, D.; Perez-Posada, A.; Garcia-Castro, H.; Solana, J.

10.1101/2024.02.28.581916 — systems biology — Posted on 2024-03-02

4940 A novel tomato inter-specific (Solanum lycopersicum var. cerasiforme and S. pimpinellifolium) MAGIC population facilitates trait association and candidate gene discovery in untapped exotic germplasm

Arrones, A.; Antar, O.; Pereira-Dias, L.; Solana, A.; Ferrante, P.; Aprea, G.; Plazas, M.; Prohens, J.; Diez, M. J.; Giuliano, G.; Gramazio, P.; Vilanova, S.

10.1101/2024.02.28.582481 — plant biology — Posted on 2024-03-02

4941 Super Pangenome of Grapevines Empowers Improvement of the Oldest Domesticated Fruit

Guo, L.; Wang, X.; Ayhan, D. H.; Rhaman, M. S.; Yan, M.; Jiang, J.; Wang, D.; Zheng, W.; Mei, J.; Ji, W.; Jiao, J.; Chen, S.; Sun, J.; Yi, S.; Meng, D.; Wang, J.; Bhuiyan, M. N.; Qin, G.; Guo, L.; Yang, Q.; Zhang, X.; Sun, H.; Liu, C.; Ye, W.

10.1101/2024.02.28.582440 — plant biology — Posted on 2024-03-02

4942 Survival of tardigrades (Hypsibius exemplaris) to subzero temperatures depends on exposure intensity, duration, and ice-nucleation--as shown by large-scale mortality dye-based assays

Lyons, A. M.; Roberts, K. T.; Williams, C. M.

10.1101/2024.02.28.582259 — physiology — Posted on 2024-03-02

4943 Next Generation Neuropeptide Y Receptor Small Molecule Agonists Inhibit Mosquito Biting Behavior

Zeledon, E. V.; Baxt, L. A.; Khan, T. A.; Michino, M.; Miller, M.; Huggins, D. J.; Jiang, C. S.; Vosshall, L. B.; Duvall, L. B.

10.1101/2024.02.28.582529 — pharmacology and toxicology — Posted on 2024-03-02

4944 Identification of microRNAs regulated by E2F transcription factors in human pluripotent stem cells

Varela, M. S. R.; Vautier, M. F.; Mucci, S.; Isaja, L.; Fernandez, E. A.; Sevlever, G. E.; Scassa, M. E.; Romorini, L.

10.1101/2024.02.28.582539 — developmental biology — Posted on 2024-03-02

4945 Learning probability distributions of sensory inputswith Monte Carlo Predictive Coding

Oliviers, G.; Bogacz, R.; Meulemans, A.

10.1101/2024.02.29.581455 — neuroscience — Posted on 2024-03-02

4946 Expression of fibroblast activation protein-α in human deep venous thrombus

Oguri, N.; Gi, T.; Nakamura, E.; Furukoji, E.; Goto, H.; Maekawa, K.; Tsuji, A. B.; Nishii, R.; Aman, M.; Moriguchi-Goto, S.; Sakae, T.; Azuma, M.; Yamashita, A.

10.1101/2024.02.27.582425 — pathology — Posted on 2024-03-02

4947 Nanogap Solid-State Single-Molecule Detection at Mars, Europa, and Microgravity Conditions

Ramirez-Colon, J. L.; Johnson, E.; Duzdevich, D.; Lee, S.; Soderblom, J.; Zuber, M. T.; Taniguchi, M.; Ohshiro, T.; Komoto, Y.; Carr, C. E.

10.1101/2024.02.29.582359 — biophysics — Posted on 2024-03-02

4948 PNAbind: Structure-based prediction of protein-nucleic acid binding using graph neural networks

Sagendorf, J. M.; Mitra, R.; Huang, J.; Chen, X. S.; Rohs, R.

10.1101/2024.02.27.582387 — bioinformatics — Posted on 2024-03-02

4949 CZ ID: a cloud-based, no-code platform enabling advanced long read metagenomic analysis

Simmonds, S. E.; Ly, L.; Lim, R.; Morse, T.; Thakku, S. G.; Rosario Cora, K.; Caballero Perez, J.; Puschnik, A. S.; Mwakibete, L.; Hickey, S.; Beaulaurier, J.; Tato, C.; CZ ID Team, ; Kalantar, K.

10.1101/2024.02.29.579666 — bioinformatics — Posted on 2024-03-02

4950 Phospho-Tune: Enhanced Structural Modeling of Phosphorylated Protein Interactions

Glukhov, E.; Averkava, V.; Kotelnikov, S.; Stepanenko, D.; Nguyen, T.; Mitchell, J. C.; Simmerling, C.; Vajda, S.; Emili, A.; Padhorny, D.; Kozakov, D.

10.1101/2024.02.29.582580 — bioinformatics — Posted on 2024-03-02

4951 PopGenPlayground: a population genomics analysis pipeline

Wolfsberger, W. W.; Shchubelka, K.; Oleksyk, O. T.; Hasynets, Y.; Patskun, S.; Vakerych, M.; Kish, R.; Mirutenko, V.; Mirutenko, V.; Cotoraci, C. A.; Pop, C.; Neagu, O.; Balta, C.; Herman, H.; Mare, P.; Dumitra, S.; Papiu, H.; Hermenean, A.; Oleksyk, T. K.

10.1101/2024.02.27.582400 — bioinformatics — Posted on 2024-03-02

4952 Expansion microscopy for super-resolution imaging of collagen-abundant tissues

Chuang, Y.-H.; Wu, Y.-F.; Lin, Y.-H.; Zhou, Y.-X.; Hsu, S.-C.; Lin, S.-J.; Chu, L.-A.

10.1101/2024.02.28.582497 — bioengineering — Posted on 2024-03-02

4953 Imaging of cellular dynamics in vitro and in situ: from a whole organism to sub-cellular imaging with self-driving, multi-scale microscopy

Daetwyler, S.; Mazloom-Farsibaf, H.; Zhou, F. Y.; Segal, D.; Sapoznik, E.; Westcott, J. M.; Brekken, R. A.; Danuser, G.; Fiolka, R. P.

10.1101/2024.02.28.582579 — bioengineering — Posted on 2024-03-02

4954 The fungal protein Jps1 facilitates unconventional protein secretion through a direct phosphoinositide interaction

Dali, S.; Schultz, M.; Koester, M.; Kamel, M.; Busch, M.; Steinchen, W.; Haensch, S.; Reiners, J.; Smits, S.; Kedrov, A.; Altegoer, F.; Schipper, K.

10.1101/2024.02.29.582524 — biochemistry — Posted on 2024-03-02

4955 Variables affecting acquisition and maintenance of operant ethanol self-administration in male and female Long-Evans rats

Wheeler, S. R.; Pitock, J. R.; Ayala, A. P.; Hou, S.; Soto, N. M. A.; Glover, E. J.

10.1101/2024.02.29.581642 — neuroscience — Posted on 2024-03-02

4956 Light-directed evolution of dynamic, multi-state, and computational protein functionalities

Rahi, S. J.; Gligorovski, V.; Labagnara, M.

10.1101/2024.02.28.582517 — synthetic biology — Posted on 2024-03-02

4957 3D Transcranial ultrasound localization microscopy reveals major arteries in the sheep brain

Coudert, A.; Denis, L.; Chavignon, A.; Bodard, S.; Naveau, M.; Pro Sistiaga, P.; Saulnier, R.; Orset, C.; Vivien, D.; Chappard, C.; Couture, O.

10.1101/2024.02.28.582489 — physiology — Posted on 2024-03-02

4958 Marine Origin of the Arachnid Brain Reveals Early Divergence of Chelicerata

Strausfeld, N. J.; Hirth, F.

10.1101/2024.02.27.582391 — paleontology — Posted on 2024-03-02

4959 Platinum drug reprogramming of protein phosphorylation

Qi, L.; Hou, Y.; Luo, Q.; Liu, X.; Zhang, Y.; Jia, F.; Fang, T.; Zhao, Y.; Wang, F.; Xu, Y.; Li, X.; Yu, W.; Wang, S.; Xin, B.; Sadler, P.

10.1101/2024.02.28.582513 — cancer biology — Posted on 2024-03-02

4960 PRMT5 inhibition preferentially targets MYCN-amplified neuroblastoma via altered transcriptional and splicing programmes regulating key cancer cell fitness pathways.

10.1101/2024.02.28.582087 — cancer biology — Posted on 2024-03-02

4961 Karyotype Evolution in Response to Chemoradiotherapy and Upon Recurrence of Esophageal Adenocarcinomas.

van der Sluis, K.; Sandick, J. W.; Koemans, W. J.; van den Bosch, T.; Broeks, A.; Peters, D.; Seignette, I. M.; Rausch, C. R.; van Dijk, E.; Snaebjornsson, P.; van den Berg, J. G.; van Grieken, N. C. T.; Ylstra, B.; Carvalho, B.; Miedema, D. M.; Kodach, L. L.

10.1101/2024.02.28.582275 — bioinformatics — Posted on 2024-03-02

4962 Machine Learning Classification of 53BP1 Foci

Benitez-Jones, M. X.; Keegan, S.; Jamshahi, S.; Fenyo, D.

10.1101/2024.02.28.582150 — bioinformatics — Posted on 2024-03-02

4963 Freeing P300-Based Brain-Computer Interfaces from Daily Calibration by Extracting Daily Common ERPs

Heo, D.; Kim, S.-P.

10.1101/2024.03.02.581675 — bioengineering — Posted on 2024-03-02

4964 Learning-Based Estimation of Fitness Landscape Ruggedness for Directed Evolution

Towers, S.; James, J.; Steel, H.; Kempf, I.

10.1101/2024.02.28.582468 — bioengineering — Posted on 2024-03-02

4965 Quantitative analysis of cis-regulatory elements in transcription with KAS-ATAC-seq

Lyu, R.; Gao, Y.; Wu, T.; Ye, C.; Wang, P.; He, C.

10.1101/2024.02.29.582869 — genomics — Posted on 2024-03-02

4966 ROUA Database: 300 Human Genomes from the border of Ukraine and Romania

Shchubelka, K. K.; Wolfsberger, W.; Oleksyk, O.; Hasynets, Y.; Patskun, S.; Vakerych, M.; Kish, R.; Mirutenko, V.; Mirutenko, V.; Cotoraci, C. A.; Pop, C.; Neagu, O.; Balta, C.; Herman, H.; Mare, P.; Dumitra, S.; Papiu, H.; Hermenean, A.; Oleksyk, T. K.

10.1101/2024.02.27.582437 — genomics — Posted on 2024-03-02

4967 Arctic greening drives changes in the diet and gut microbiome of a resident herbivore with consequences for fitness

Kamenova, S.; Albon, S.; Loe, L. E.; Irvine, J.; Langvatn, R.; Gusarova, G.; de Muinck, E.; Trosvik, P.

10.1101/2024.02.27.582426 — ecology — Posted on 2024-03-02

4968 Single nucleus transcriptomics supports a role for CCNA2-induced human adult cardiomyocyte cytokinesis

Bouhamida, E.; Vadakke-Madathil, S.; Mathiyalagan, P.; Ranjan, A.; Sherman, C.; Miller, P. E.; Ghetti, A.; Abi-Gerges, N.; Chaudhry, H. W.

10.1101/2024.03.01.583057 — cell biology — Posted on 2024-03-02

4969 RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons

Kofman, S. B.; Chu, L. H.; Ames, J. M.; Chavarria, S. D.; Lichauco, K.; Daniels, B. P.; Oberst, A.

10.1101/2024.02.29.582857 — immunology — Posted on 2024-03-02

4970 Single-nucleus Multiomic Analyses Identifies Gene Regulatory Dynamics of Phenotypic Modulation in Human Aneurysmal Aortic Root

Liu, X.; Zeng, Q.; Yang, H.; Li, W.; Chen, Q.; Yin, K.; Pan, Z.; Wang, K.; Luo, M.; Shu, C.; Zhou, Z.

10.1101/2024.02.27.582442 — pathology — Posted on 2024-03-02

4971 Aberrant subcellular localization of mismatch repair protein MLH1 dysregulates the cell cycle to create new therapeutic opportunities

Haricharan, S.; Mazumder, A.; DeWitt, T.; Oropeza, E.; Punturi, N.; Lozano, D.; Sajjadi, E.; Guerini-Rocco, E.; Venetis, K.; Ivanova, M.; Mane, E.; Fusco, N.

10.1101/2024.02.27.582389 — cancer biology — Posted on 2024-03-02

4972 Easy, fast and reproducible Stochastic Cellular Automata with 'chouca'

Genin, A.; Dupont, G.; Valencia, D.; Zucconi, M.; Avila-Thieme, M. I.; Navarrete, S.; Wieters, E.

10.1101/2023.11.08.566206 — ecology — Posted on 2024-03-02

4973 Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes

Byun, M. J.; Armon, R.; Souza, T.; Anderson, H. D.; Saleem, A.; Pauls, S. D.

10.1101/2024.03.01.582966 — cell biology — Posted on 2024-03-02

4974 5'-untranslated region sequences enhance plasmid-based protein production in Sulfolobus acidocaldarius

Kuschmierz, L.; Wagner, A.; Busche, T.; Kalinowski, J.; Braesen, C.; Siebers, B.

10.1101/2024.03.01.582787 — molecular biology — Posted on 2024-03-02

4975 Promoting Longevity in Aged Liver through NLRP3 Inflammasome Inhibition Using Tauroursodeoxycholic Acid (TUDCA) and SCD Probiotics

Baba, B.; Ceylani, T.; Acikgoz, E.; Gurbanov, R.; Keskin, S.; Samgane, G.; Tombuloglu, H.; Teker, H. T.

10.1101/2024.02.27.582399 — molecular biology — Posted on 2024-03-02

4976 Cellulose fermentation by the gut microbiota is likely not essential for the nutrition of millipedes

Angel, R.; Nweze, J. E.; Gupta, S.; Salcher, M. M.; Sustr, V.; Horvathova, T.

10.1101/2024.03.01.582937 — microbiology — Posted on 2024-03-02

4977 Cytochrome oxidase requirements in Bordetella reveal insights into evolution towards life in the mammalian respiratory tract

McKay, L. S.; Spandrio, A. R.; Johnson, R. M.; Sobran, M. A.; Marlatt, S.; Mote, K. B.; Dedloff, M. R.; Nash, Z. M.; Julio, S. M.; Cotter, P. A.

10.1101/2024.02.29.582880 — microbiology — Posted on 2024-03-02

4978 Evolution of pH-sensitive transcription termination during adaptation to repeated long-term starvation.

Worthan, S. B.; McCarthy, R. D. P.; Delaleau, M.; Stikeleather, R.; Bratton, B. P.; Boudvillain, M.; Behringer, M. G.

10.1101/2024.03.01.582989 — microbiology — Posted on 2024-03-02

4979 Fes-deficient macrophages enhance CD8+ T cell priming and tumour control through increased proinflammatory cytokine production and presentation

Laight, B. J.; Dmytryk, N.; Harper, D.; Zhang, C. S.; Garven, A.; Simpson, A. L.; Berman, D. M.; Kment, J.; Alotaibi, F.; Shi, C.; Gao, Y.; Vlasschaert, C.; LeBrun, D.; Tyryshkin, K.; Craig, A.; Basta, S.; Koti, M.; Greer, P. A.

10.1101/2024.02.27.581601 — immunology — Posted on 2024-03-02

4980 Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity

Gabrielle, M.; Yudin, Y.; Wang, Y.; Su, X.; Rohacs, T.

10.1101/2024.03.01.582964 — neuroscience — Posted on 2024-03-02

4981 Seminal root angle is associated with root system architecture in durum wheat

Kang, Y.; Rambla, C.; Haeften, S.; Fu, B.; Akinlade, O.; Potgieter, A.; Borrell, A.; Mace, E.; Jordan, D.; Alahmad, S.; Hickey, L.

10.1101/2024.02.27.582216 — plant biology — Posted on 2024-03-02

4982 Sterile kidney tissue injury induces neutrophil swarming in lung alveolar capillaries

Komaru, Y.; Ning, L.; Lama, C.; Suresh, A.; Kefaloyianni, E.; Miller, M. J.; Herrlich, A.

10.1101/2024.02.27.582396 — physiology — Posted on 2024-03-02

4983 PIKfyve controls dendritic cell function and tumor immunity

Choi, J. E.; Qiao, Y.; Kryczek, I.; Yu, J.; Gurkan, J.; Bao, Y.; Gondal, M.; Tien, J. C.-Y.; Maj, T.; Yazdani, S.; Parolia, A.; Xia, H.; Zhou, J.; Wei, S.; Grove, S.; Vatan, L.; Lin, H.; Li, G.; Zheng, Y.; Zhang, Y.; Cao, X.; Su, F.; Wang, R.; He, T.; Cieslik, M.; Green, M. D.; Zou, W.; Chinnaiyan, A. M.

10.1101/2024.02.28.582543 — cancer biology — Posted on 2024-03-02

4984 Rare SNP in the HELB gene interferes with RPA interaction and cellular function of HELB

Osei, B.; May, B. H.; Stiefel, C. M.; West, K. L.; Zafar, M. K.; Thomoson, M. D.; Bergstrom, E.; Leung, J. W.; Enemark, E. J.; Byrd, A. K.

10.1101/2024.02.27.582415 — biochemistry — Posted on 2024-03-02

4985 Premeiotic endoreplication is the mechanism of obligate parthenogenesis in rock lizards of the genus Darevskia

Dedukh, D.; Altmanova, M.; Petrosyan, R.; Arakelyan, M.; Galoyan, E.; Kratochvil, L.

10.1101/2024.02.27.582286 — evolutionary biology — Posted on 2024-03-02

4986 Label-free imaging of cellular organization in living mammalian cells via external apodization phase-contrast microscopy

Sari, L. N.; Miyamoto, T.; Nishimura, T.; Kainoh, K.; Onodera, N.; Kano, M.; Masuda, M.; Tamura, Y.; Hayashi, Y.; Yamamoto, Y.; Takahashi, S.-I.; Mishima, Y.; Yoneyama, Y.; Takeuchi, Y.; Ohno, H.; Ohashi, Y.; Sekiya, M.; Matsuzaka, T.; Shimano, H.

10.1101/2024.03.01.582671 — cell biology — Posted on 2024-03-02

4987 Analysis of Infiltrating Immune Cells Following Intervertebral Disc Injury Reveals Recruitment of Gamma-Delta (????) T cells in Female Mice

Clayton, S. W.; Walk, R. E.; Mpofu, L.; Easson, G. W.; Tang, S. Y.

10.1101/2024.03.01.582950 — cell biology — Posted on 2024-03-02

4988 Deciphering mixed infections by plant RNA virus and reconstructing complete genomes simultaneously present within-host

BANGRATZ, M.; COMTE, A.; BILLARD, E.; GUIGMA, A. K.; GANDOLFI, G.; KASSANKOGNO, A. I.; SEREME, D.; POULICARD, N.; TOLLENAERE, C.

10.1101/2024.02.29.582683 — molecular biology — Posted on 2024-03-02

4989 PTCHD1 interacts with the SNARE-associated protein SNAPIN in vitro via its first exoplasmic loop

Pastore, S. F.; Xie, C. T. Y.; Muhammad, T.; El-masri, S.; Frankland, P.; Hamel, P. A.; Vincent, J. B.

10.1101/2024.02.29.582618 — molecular biology — Posted on 2024-03-02

4990 A gnotobiotic mouse model with divergent equol-producing phenotype: potential for determining microbial-driven health impacts of soy isoflavone daidzein

Cross, T.-W. L.; Leonard, L. M.; Simpson, A. M. R.; Reddivari, L.

10.1101/2024.03.01.582818 — microbiology — Posted on 2024-03-02

4991 Targeting Iron - Respiratory Reciprocity Promotes Bacterial Death

Sharifian Gh., M.; Norouzi, F.; Sorci, M.; Zaid, T. S.; Pier, G. B.; Achimovich, A. M.; Ongwae, G. M.; Liang, B.; Ryan, M.; Lemke, M.; Belfort, G.; Gadjeva, M.; Gahlmann, A.; Pires, M. M.; Venter, H.; Harris, T. E.; Laurie, G. W.

10.1101/2024.03.01.582947 — microbiology — Posted on 2024-03-02

4992 Investigating cross-sectional and longitudinal relationships between brain structure and distinct dimensions of externalizing psychopathology in the ABCD Sample

Propp, L.; Nakua, H.; Bedard, A.-C. V.; Sanches, M.; Ameis, S. H.; Andrade, B. F.

10.1101/2024.03.01.583021 — neuroscience — Posted on 2024-03-02

4993 Intrinsic functional connectivity among memory networks does not predict individual differences in narrative recall

Kurkela, K.; Ritchey, M.

10.1101/2023.08.31.555768 — neuroscience — Posted on 2024-03-02

4994 Hominin brain size increase has emerged from within-species encephalization

Puschel, T. A.; Nicholson, S. L.; Baker, J.; Barton, R. A.; Venditti, C.

10.1101/2024.02.29.582715 — paleontology — Posted on 2024-03-02

4995 PTEN loss in glioma cell lines leads to increased extracellular vesicle biogenesis and PD-L1 cargo in a PI3K-dependent manner

Sanchez, J. C.; Pierpont, T. M.; Argueta-Zamora, D.; Wilson, K. F.; August, A.; Cerione, R. A.

10.1101/2023.07.26.550575 — cancer biology — Posted on 2024-03-02

4996 Distinct roles of the major binding residues in the cation-binding pocket of MelB

Hariharan, P.; Bakhtiiari, A.; Liang, R.; Guan, L.

10.1101/2024.02.27.582382 — biophysics — Posted on 2024-03-02

4997 On the dynamic contact angle of capillary-driven microflows in open channels

Tokihiro, J. C.; McManamen, A. M.; Phan, D. N.; Thongpang, S.; Blake, T. D.; Theberge, A. B.; Berthier, J.

10.1101/2023.04.24.537941 — bioengineering — Posted on 2024-03-02

4998 Designed fluorescent protein cages as fiducial markers for targeted cell imaging

Gee, M.; Atai, K.; Coller, H. A.; Yeates, T. O.; Castells-Graells, R.

10.1101/2024.02.28.582585 — biochemistry — Posted on 2024-03-02

4999 The antioxidants esculetin and quercetin modulate differently redox balance in human NB4 leukemia cells

Rubio, V.; Garcia-Perez, A. I.; Herraez, A.; Puebla, L.; Diez, J. C.

10.1101/2024.02.28.578584 — biochemistry — Posted on 2024-03-02

5000 Disordered proteins interact with the chemical environment to tune their protective function during drying

KC, S.; Nguyen, K. H.; Nicholson, V.; Walgren, A.; Trent, T.; Gollub, E.; Ramero, S.; Holehouse, A. S.; Sukenik, S.; Boothby, T. C.

10.1101/2024.02.28.582506 — biochemistry — Posted on 2024-03-02

5001 A DNA base-specific sequence interposed between CRX and NRL contributes to RHODOPSIN expression.

Maritato, R.; Medugno, A.; D'Andretta, E.; De Riso, G.; Lupo, M.; Botta, S.; Marrocco, E.; Renda, M.; Sofia, M.; Mussolino, C.; Bacci, M. L.; Surace, E. M.

10.1101/2023.12.22.573078 — genetics — Posted on 2024-03-02

5002 Rewinding the developmental tape shows how bears break a developmental rule

Stenberg, O. E.; Moustakas-Verho, J. E.; Jernvall, J.

10.1101/2024.02.29.582676 — evolutionary biology — Posted on 2024-03-02

5003 A DIFFERENTIAL REQUIREMENT FOR THE CILIOPATHY GENE RPGRIP1L IN HUMAN AND MOUSE SPINAL PROGENITOR FATE SPECIFICATION

Wiegering, A.; Anselme, I.; Brunetti, L.; Metayer-Derout, L.; Calderon, D.; Thomas, S.; Nedelec, S.; Eschstruth, A.; Schneider-Maunoury, S.; STEDMAN, A.

10.1101/2024.02.28.582477 — developmental biology — Posted on 2024-03-02

5004 CRISPR-Cas9 editing efficiency in fission yeast is not limited by homology search and is improved by combining gap-repair with fluoride selection

Fernandez, R.; Berro, J.

10.1101/2024.03.01.582946 — cell biology — Posted on 2024-03-02

5005 Methionine cycle in a pair of serotonergic neurons regulates diet-dependent behavior and longevity through a neuron-gut signaling

Rahman, S. S.; Bhattacharjee, S.; Prakash, G.; Motwani, S.; Nair, T.; Keerthana, R. S.; Mukhopadhyay, A.

10.1101/2024.03.01.582891 — cell biology — Posted on 2024-03-02

5006 The antifungal activity of cymoxanil is associated with proton pump inhibition and disruption of plasma membrane potential

Mendes, F.; Meyer, H.; Amaral, L.; Castro, B.; Schuldiner, M.; Sousa, M. J.; Chaves, S.

10.1101/2024.03.01.583004 — cell biology — Posted on 2024-03-02

5007 A quantitative pipeline to assess secretion of human leptin coding variants reveals mechanisms underlying leptin deficiencies

Baird, H. J. M.; Shun-Shion, A. S.; Mendes De Oliveira, E.; Stalder, D.; Eden, J.; Chambers, J. E.; Farooqi, I. S.; Gershlick, D. C.; Fazakerley, D. J.

10.1101/2024.03.01.582913 — cell biology — Posted on 2024-03-02

5008 Eliminating elevated p53 signaling in Lmna-mutant mice fails to rescue skeletal muscle defects or extend survival

Kirby, T. J.; Zahr, H. C.; Fong, E. H. H.; Lammerding, J.

10.1101/2022.07.08.499329 — cell biology — Posted on 2024-03-02

5009 A proximity complementation assay to identify small molecules that enhance the traffic of ABCA4 misfolding variants.

Piccolo, D.; Zarouchlioti, C.; Bellingham, J.; Guarascio, R.; Ziaka, K.; Molday, R. S.; Cheetham, M. E.

10.1101/2024.03.01.582985 — molecular biology — Posted on 2024-03-02

5010 Erythropoietin production in embryonic neural cells is controlled by hypoxia-inducible factors and histone deacetylases in an undifferentiated state

Iwamura, Y.; Nakai, T.; Kato, K.; Ishioka, H.; Yamamoto, M.; Hirano, I.; Suzuki, N.

10.1101/2024.02.28.582479 — molecular biology — Posted on 2024-03-02

5011 Under the radar: differential responses of bed bugs to an entomopathogen, environmental bacteria, and a human pathogen

Walt, H. K.; Bronzato-Badial, A.; Maedo, S. E.; Hinton, J. A.; King, J. G.; Pietri, J.; Hoffmann, F. G.

10.1101/2024.02.28.582586 — molecular biology — Posted on 2024-03-02

5012 Plasmid-encoded insertion sequences promote rapid adaptation in clinical enterobacteria

Sastre-Dominguez, J.; DelaFuente, J.; Toribio-Celestino, L.; Herencias, C.; Herrador-Gomez, P.; Costas, C.; Hernandez-Garcia, M.; Canton, R.; Rodriguez-Beltran, J.; Santos-Lopez, A.; San Millan, A.

10.1101/2024.03.01.582297 — microbiology — Posted on 2024-03-02

5013 Sticking together: Independent evolution of biofilm formation in different species of staphylococci has occurred multiple times via different pathways

Crossman, L.; Sims, L. P.; Dean, R.; Felgate, H. M.; Diaz Calvo, T.; Hill, C. L.; McNamara, I.; Webber, M. A.; Wain, J. A.

10.1101/2024.03.01.582901 — microbiology — Posted on 2024-03-02

5014 Release of P-TEFb from the Super Elongation Complex promotes HIV-1 latency reversal

Cisneros, W. J.; Walter, M.; Soliman, S. H. A.; Simons, L. M.; Cornish, D.; Halle, A. W.; Kim, E.-Y.; Wolinsky, S. M.; Shilatifard, A.; Hultquist, J. F.

10.1101/2024.03.01.582881 — microbiology — Posted on 2024-03-02

5015 Tick-borne pathogens identified in Hyalomma marginatum (Acari: Ixodidae) collected from various vertebrate hosts in the South of France

Bernard, C.; Pollet, T.; Galon, C.; Joly Kukla, C.; Cicculli, V.; Falchi, A.; Grech-Angelini, S.; Poli, P.-E.; Bastien, M.; Combes, B.; Moutailler, S.; Holzmuller, P.; Vial, L.

10.1101/2024.03.01.582933 — microbiology — Posted on 2024-03-02

5016 Siderophore piracy enables the nasal commensal Staphylococcus lugdunensis to antagonize the pathogen Staphylococcus aureus

Rosenstein, R.; Salazar, B. O. T.; Sauer, C.; Heilbronner, S.; Krismer, B.; Peschel, A.

10.1101/2024.02.29.582731 — microbiology — Posted on 2024-03-02

5017 A platform for the recombinant production of Group A Streptococcus glycoconjugate vaccines

Ajay Castro, S.; Passmore, I. J.; Ndeh, D.; Shaw, H. A.; Ruda, A.; Burns, K.; Thomson, S.; Nagar, R.; Alagesan, K.; Lucas, K.; Abouelhadid, S.; Reglinski, M.; Schwarz- Linek, U.; Mawas, F.; Widmalm, G.; Wren, B. W.; Dorfmueller, H. C.

10.1101/2024.03.01.582896 — microbiology — Posted on 2024-03-02

5018 Differential gene expression and chromatin accessibility in the rat medial prefrontal cortex mediating individual variability in vulnerability to opioid use

Liu, S. X.; Muelken, P.; Maxim, Z. L.; Ramakrishnan, A.; Estill, M. S.; LeSage, M. G.; Smethells, J. R.; Shen, L.; Tran, P. V.; Harris, A. C.; Gewirtz, J. C.

10.1101/2024.02.29.582799 — neuroscience — Posted on 2024-03-02

5019 Orderly specification and precise laminar deployment of cortical glutamatergic projection neuron types through intermediate progenitors

Huilgol, D.; Levine, J. M.; Galbavy, W.; Wang, B.-S.; Huang, Z. J.

10.1101/2024.03.01.582863 — neuroscience — Posted on 2024-03-02

5020 Gluk4-containing kainate receptors regulate synaptic communication in the motor cortex and reduce axon degeneration in adult mice

Ricci, R.; Fletcher, J. L.; Makowiecki, K.; Pepper, R.; Fortune, A.; Cullen, C. L.; Connelly, W. M.; Charlesworth, J.; Blackburn, N. B.; Pitman, K. A.; Young, K.

10.1101/2024.02.29.582867 — neuroscience — Posted on 2024-03-02

5021 NEK1 haploinsufficiency impairs ciliogenesis in human iPSC-derived motoneurons and brain organoids

Sorce, M. N.; Invernizzi, S.; Casiraghi, V.; Santangelo, S.; Lattuada, C.; Podini, P.; Brusati, A.; Silva, A.; Peverelli, S.; Quattrini, A.; Silani, V.; Bossolasco, P.; Ratti, A.

10.1101/2024.02.29.582696 — neuroscience — Posted on 2024-03-02

5022 Macroscale brain states support the control of semantic cognition

Wang, X.; Krieger-Redwood, K.; Cui, Y.; Smallwood, J.; Du, Y.; Jefferies, E.

10.1101/2024.02.29.582250 — neuroscience — Posted on 2024-03-02

5023 Prothrombin Knockdown Protects Podocytes and Reduces Proteinuria in Glomerular Disease

Waller, A. P.; Wolfgang, K. J.; Pruner, I.; Stevenson, Z. S.; Abdelghani, E.; Muralidharan, K.; Wilkie, T. K.; Blissett, A. R.; Calomeni, E. P.; Vetter, T. A.; Brodsky, S. V.; Smoyer, W. E.; Nieman, M. T.; Kerlin, B. A.

10.1101/2023.06.20.544360 — physiology — Posted on 2024-03-02

5024 Swimming ability and flagellar motility of sperm packets of the volvocine green alga Pleodorina starrii

Kage, A.; Takahashi, K.; Nozaki, H.; Higashiyama, T.; Baba, S. A.; Nishizaka, T.

10.1101/2023.06.08.544266 — biophysics — Posted on 2024-03-02

5025 A Structured Illumination Microscopy Framework with Spatial-Domain Noise Propagation.

Saurabh, A.; Brown, P. T.; Bryan, J. S.; Fox, Z. R.; Kruithoff, R.; Thompson, C.; Kural, C.; Shepherd, D. P.; Presse, S. P.

10.1101/2023.12.07.570701 — biophysics — Posted on 2024-03-02

5026 Metabolic phenotyping of healthy and diseased human RPE cells

Rizwan, S.; Toothman, B.; Li, B.; Engel, A. J.; Lim, R. R.; Chao, J. R.; Du, J.

10.1101/2024.02.28.582405 — biochemistry — Posted on 2024-03-02

5027 Interpreting cis-regulatory mechanisms from genomic deep neural networks using surrogate models

Seitz, E.; McCandlish, D. M.; Kinney, J. B.; Koo, P. K.

10.1101/2023.11.14.567120 — genomics — Posted on 2024-03-02

5028 Integrated single-nuclei and spatial transcriptomic analysis reveals propagation of early acute vein harvest and distension injury signaling pathways following arterial implantation

Michaud, M. E.; Mota, L.; Bakhtiari, M.; Thomas, B. E.; Tomeo, J.; Pilcher, W.; Contreras, M.; Ferran, C.; Bhasin, S.; Pradhan-Nabzdyk, L.; LoGerfo, F. W.; Liang, P.; Bhasin, M.

10.1101/2023.10.31.564995 — genomics — Posted on 2024-03-02

5029 Genomic fingerprints of the world's soil ecosystems

Graham, E. B.; Garayburu-Caruso, V. A.; Wu, R.; Zheng, J.; Jones, G.; McClure, R.

10.1101/2023.11.02.563126 — ecology — Posted on 2024-03-02

5030 Sputum production and salivary microbiome in COVID-19 patients reveals oral-lung axis

Lu, K. Y.-F.; Alqaderi, H.; Bin Hasan, S.; Alhazmi, H.; Alghounaim, M.; Devarajan, S.; Freire, M.; Altabtbaei, K.

10.1101/2024.02.29.582705 — microbiology — Posted on 2024-03-01

5031 T7 RNA polymerase-independent expression of reporter genes from a T7 promoter-driven SARS-CoV-2 replicon-encoding DNA in human cells

Friedhoff, R.; Elfayres, G.; Merindol, N.; Desgagne-Penix, I.; Berthoux, L.

10.1101/2024.03.01.582915 — microbiology — Posted on 2024-03-01

5032 High-dimensional mass cytometry reveals stemness state heterogeneity in pancreatic ductal adenocarcinoma

Ervin, E. H.; Ahern, D.; Liu, F.; Rendek, A.; Soonawalla, Z.; Oppermann, U.; Hulley, P.; Pauklin, S.

10.1101/2024.02.27.582358 — cancer biology — Posted on 2024-03-01

5033 The diversity of clinical Mycobacterium abscessus isolates in morphology, glycopeptidolipids and infection rates in a macrophage model

Pichler, V.; Dalkilic, L.; Shoaib, G.; Shapira, T.; Rankine-Wilson, L.; Boudehen, Y.-M.; Chao, J.; Sexton, D. L.; Prieto, M. D.; Quon, B.; Tocheva, E. I.; Kremer, L.; Hsiao, W.; Av-Gay, Y.

10.1101/2024.02.29.582856 — microbiology — Posted on 2024-03-01

5034 The riboflavin biosynthetic pathway as a novel target for antifungal drugs against Candida species

Nysten, J.; Peetermans, A.; Vaneynde, D.; Demuyser, L.; Van Dijck, P.

10.1101/2024.03.01.582991 — microbiology — Posted on 2024-03-01

5035 Profiling of linear B-cell epitopes against human coronaviruses in pooled sera sampled early in the COVID-19 pandemic

Bach, E.; Ghanizada, M.; Kirkby, N.; Buus, S.; Osterbye, T.

10.1101/2024.02.29.582263 — immunology — Posted on 2024-03-01

5036 Dual agonism of sodium iodide symporter function in vivo

Brookes, K.; Thornton, C. M.; Zha, L.; Kim, J.; Small, B.; Manivannan, S.; Nieto, H. R.; Adcock, H.; Bottegoni, G.; Cox, L. R.; Kannappan, V.; Wang, W.; Gorvin, C. M.; Jhiang, S.; Ringel, M. D.; Campbell, M. J.; Sunassee, K.; Blower, P. J.; Boelaert, K.; Smith, V. E.; Read, M. L.; McCabe, C. J.

10.1101/2024.02.27.582332 — cancer biology — Posted on 2024-03-01

5037 Increased dosage of wild-type KRAS protein drives KRAS-mutant lung tumorigenesis and drug resistance

Ivanisevic, T.; Magits, W.; Ma, Y.; Zhao, P.; Van Boxel, E.; Lechat, B.; Stites, E.; Vande Velde, G.; Sewduth, R.; Sablina, A.

10.1101/2024.02.27.582346 — cancer biology — Posted on 2024-03-01

5038 Direct pharmacological AMPK activation inhibits mucosal SARS-CoV-2 infection by reducing lipid metabolism, restoring autophagy flux and the type I IFN response

Cottignies-Calamarte, A.; Marteau, F.; Belouzard, S.; Dubuisson, J.; Tudor, D.; Viollet, B.; Bomsel, M.

10.1101/2024.02.29.582713 — immunology — Posted on 2024-03-01

5039 Compartment-Specific Antibody Correlates of Protection to SARS-CoV-2 Omicron in Macaques

Tong, X.; Wang, Q.; Jung, W.; Chicz, T. M.; Blanc, R.; Parker, L. J.; Barouch, D. H.; McNamara, R. P.

10.1101/2024.03.01.582951 — immunology — Posted on 2024-03-01

5040 PROTAC-mediated dual degradation of BCL-xL and BCL-2 is a highly effective therapeutic strategy in small-cell lung cancer

Khan, S.; Cao, L.; Wiegand, J.; Zhang, P.; Zajac-Kaye, M.; Kaye, F. J.; Zheng, G.; Zhou, D.

10.1101/2024.02.27.582353 — cancer biology — Posted on 2024-03-01

5041 High-throughput algorithm predicts F-Type ATP synthase rotor ring stoichiometries of 8 to 27 protomers

Osipov, S.; Zinoviev, E.; Anuchina, A.; Kuzmin, A.; Minaeva, A.; Ryzhykau, Y.; Vlasov, A.; Gushchin, I.

10.1101/2024.02.27.582367 — bioinformatics — Posted on 2024-03-01

5042 Using machine learning to count Antarctic shag (Leucocarbo bransfieldensis) nests on images captured by Remotely Piloted Aircraft Systems

Cusick, A.; Fudala, K.; Storozenko, P. P.; Swiezewski, J.; Kaleta, J.; Oosthuizen, W. C.; Pfeifer, C.; Bialik, R. J.

10.1101/2024.02.27.582379 — ecology — Posted on 2024-03-01

5043 Determining the rate-limiting processes for cell division in Escherichia coli

Männik, J.; Kar, P.; Amarasinghe, C.; Amir, A.; Männik, J.

10.1101/2024.03.01.582948 — cell biology — Posted on 2024-03-01

5044 The Underground World of Plant Disease: How Does Rhizosphere Dysbiosis Affect Plant Health Above-ground?

Ketehouli, T.; Pasche, J.; Buttros, V.; Goss, E.; Martins, S. J.

10.1101/2024.02.27.582369 — plant biology — Posted on 2024-03-01

5045 Staphylococcus aureus lipid factors modulate melanoma clustering and invasion in zebrafish

Giese, M.; Ramakrishnan, G.; Steenberge, L.; Dovan, J.; Sauer, J.; Huttenlocher, A.

10.1101/2024.02.27.582365 — cancer biology — Posted on 2024-03-01

5046 HKDC1 Promotes Liver Cancer Stemness Under Hypoxia via Stabilizing β-Catenin

Fan, L.; Tian, C.; Yang, W.; Liu, X.; Dhungana, Y.; Tan, H.; Glazer, E. S.; Yu, J.; Peng, J.; Ma, L.; Ni, M.; Zhu, L.

10.1101/2024.02.27.581958 — cancer biology — Posted on 2024-03-01

5047 Circulating (poly)phenol metabolites in the brain: unveiling in vitro and in vivo blood-brain barrier transport

Carecho, R.; Marques, D.; Carregosa, D.; Masuero, D.; Garcia-Aloy, M.; Tramer, F.; Passamonti, S.; Vrhovsek, U.; Ventura, R.; Brito, M. A.; Nunes dos Santos, C.; Figueira, I.

10.1101/2024.02.27.582339 — biochemistry — Posted on 2024-03-01

5048 Common modes of ERK induction resolve into context specific signalling via a combination of signal duration and cell type specific transcriptional repression.

Perera, M.; Brickman, J.

10.1101/2024.02.29.582771 — developmental biology — Posted on 2024-03-01

5049 Cognate Antigen Engagement Induces HIV-1 Expression In CD4+ T Cells From People On Long-Term ART

Moskovjlevic, M.; Dragoni, F.; Board, N. L.; Wu, F.; Lai, J.; Zhang, H.; White, J. R.; Ho, R.; Lynn, K.; Tebas, P.; Mounzer, K.; Deeks, S. G.; Montaner, L. J.; Siliciano, J. D.; Simonetti, F. R.; Siliciano, R. F.

10.1101/2024.02.27.582096 — immunology — Posted on 2024-03-01

5050 Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5

Harrison, T.; Alam, N.; Farrell, B.; Quinkert, D.; Lias, A.; King, L.; Draper, S. J.; Higgins, M. K.; Campeotto, I.

10.1101/2024.02.29.582763 — immunology — Posted on 2024-03-01

5051 Complex Traits Heritability is Highly Clustered in the eQTL Bipartite Network

Stone, K. L.; Platig, J.; Quackenbush, J.; Fagny, M.

10.1101/2024.02.27.582063 — systems biology — Posted on 2024-03-01

5052 Human Foot Force Informs Balance Control Strategies when Standing on a Narrow Beam

Shiozawa, K.; Russo, M.; Lee, J.; Hogan, N.; Sternad, D.

10.1101/2024.02.27.582256 — physiology — Posted on 2024-03-01

5053 Investigating the mechanisms of antibody binding to alpha-synuclein for the treatment of Parkinson's Disease

Harrison, M. C.; Lai, P.-K.

10.1101/2024.02.27.582350 — biophysics — Posted on 2024-03-01

5054 Bioinformatic analysis of human ZPR1 gene pathogenic exome mutation

Abok, J. I.; Edwards, J. S.; Garver, W. S.

10.1101/2024.02.27.582196 — bioinformatics — Posted on 2024-03-01

5055 Generative Haplotype Prediction Outperforms Statistical Methods for Small Variant Detection in NGS Data

O'Fallon, B.; Bolia, A.; Durtschi, J.; Yang, L.; Fredrickson, E.; Best, H.

10.1101/2024.02.27.582327 — bioinformatics — Posted on 2024-03-01

5056 Arf family GTPases are present in Asgard archaea

Vargova, R.; Chevreau, R.; Alves, M.; Courbin, C.; Terry, K.; Legrand, P.; Elias, M.; Menetrey, J.; Dacks, J. B.; Jackson, C. L.

10.1101/2024.02.28.582541 — evolutionary biology — Posted on 2024-03-01

5057 High resolution live cell imaging to define ultrastructural and dynamic features of the halotolerant yeast Debaryomyces hansenii

Xelhuantzi, M. S. C.; Ghete, D.; Milburn, A.; Ioannou, S.; Mudd, P.; Calder, G.; Ramos, J.; O'Toole, P. J.; Genever, P. G.; MacDonald, C.

10.1101/2024.03.01.582977 — cell biology — Posted on 2024-03-01

5058 The USH3A causative gene clarin1 functions in Muller glia to maintain retinal photoreceptors

Nonarath, H. J. T.; Simpson, S. L.; Slobodianuk, T. L.; Collery, R. F.; Dinculescu, A.; Link, B. A.

10.1101/2024.02.29.582878 — cell biology — Posted on 2024-03-01

5059 Epigenetic programming of host lipid metabolism associates with resistance to TST/IGRA conversion after exposure to Mycobacterium tuberculosis

Dill-McFarland, K. A.; Simmons, J. D.; Peterson, G. J.; Nguyen, F. K.; Campo, M.; Benchek, P.; Stein, C.; Vaisar, T.; Mayanja-Kizza, H.; Boom, W. H.; Hawn, T.

10.1101/2024.02.27.582348 — immunology — Posted on 2024-03-01

5060 Inferring fungal growth rates from optical density data

Hameed, T.; Motsi, N.; Bignell, E.; Tanaka, R. J.

10.1101/2024.02.27.582053 — systems biology — Posted on 2024-03-01

5061 Physical-Chemical Features Selection Reveals That Differences in Dipeptide Compositions Correlate Most with Protein-Protein Interactions

Teimouri, H.; Medvedeva, A.; Kolomeisky, A. B.

10.1101/2024.02.27.582345 — bioinformatics — Posted on 2024-03-01

5062 An overview of GabRat edge disruption and its new extensions for unbiased quantification of disruptive camouflaging patterns using randomization technique

Tanahashi, M.; Lin, M.-C.; Lin, C.-P.

10.1101/2024.02.27.582325 — evolutionary biology — Posted on 2024-03-01

5063 Resting natural killer cells promote the progress of colon cancer liver metastasis by elevating tumor-derived sSCF

Mao, C.; Chen, Y.; xing, d.; zhang, t.; Mei, D.; han, z.; xie, w.; Long, C.; Lin, Y.; yu, j.; Xiang, D.; Lu, M.; shen, x.; xue, x.

10.1101/2024.02.27.582307 — immunology — Posted on 2024-03-01

5064 The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome.

Gleeson, T. A.; Kaiser, C.; Lawrence, C. B.; Brough, D.; Allan, S. M.; Green, J. P.

10.1101/2024.02.27.582284 — immunology — Posted on 2024-03-01

5065 Retrograde tracing of breast cancer-associated sensory neurons

Kallogjerovic, S.; Velazquez Quesada, I.; Hadap, R.; Gligorijevic, B.

10.1101/2024.02.26.582088 — cancer biology — Posted on 2024-03-01

5066 Macrophages foster adaptive anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction

Fuchs, K.; Armstark, I.; van Roey, R.; Hajjaj, Y.; D`Avanzo, E.; Liguori, R.; Ferrazzi, F.; Ackermann, J.; Amon, L.; Alfredo, M.; Faas, M.; Huebner, J.; Hoffmann, M. H.; Kroenke, G.; Becker, C.; Dudziak, D.; Nimmerjahn, F.; Brabletz, S.; Stemmler, M. P.; Brabletz, T.; Schuhwerk, H.

10.1101/2024.02.26.582102 — cancer biology — Posted on 2024-03-01

5067 Armored Bicistronic CAR T Cells with Dominant-negative TGF-β Receptor II to Overcome Resistance in Glioblastoma.

Li, N.; Rodriguez, J. L.; Yin, Y.; Logun, M. T.; Yu, S.; Hicks, K. A.; Zhang, V.; Zhang, L.; Xie, C.; Wang, J.; Fraietta, J. A.; Binder, Z. A.; Lin, Z.; O'Rourke, D. M.

10.1101/2024.02.26.582107 — cancer biology — Posted on 2024-03-01

5068 DACIT: Device for Axon - Cancer cell Interaction Testing in 2D and 3D

Velazquez Quesada, I.; Allison, K.; Alizadeh, V.; Hesketh, N.; Thomas, G.; Tuzel, E.; Gligorijevic, B.

10.1101/2024.02.26.582218 — cancer biology — Posted on 2024-03-01

5069 Spatial transcriptomics profiling of gallbladder adenocarcinoma: a detailed two-case study of progression from precursor lesions to cancer

Pirenne, S.; Manzano-Nunez, F.; Loriot, A.; Cordi, S.; Desmet, L.; Aydin, S.; Hubert, C.; Toffoli, S.; Limaye, N.; Sempoux, C.; Komuta, M.; Gatto, L.; Lemaigre, F. P.

10.1101/2024.02.27.582232 — cancer biology — Posted on 2024-03-01

5070 Methods for imaging intracellular calcium signals in the mouse mammary epithelium in 2- and 3-dimensions

Folacci, M.; Chalmers, S. B.; Davis, F. M.

10.1101/2024.02.27.582265 — physiology — Posted on 2024-03-01

5071 Deciphering Mechanochemical Influences of Emergent Actomyosin Crosstalk using QCM-D

Kerivan, E. M.; Amari, V. N.; Weeks, W. B.; Hardin, L. H.; Tobin, L.; Alazzam, O. Y.; Reinemann, D.

10.1101/2024.02.26.582155 — biophysics — Posted on 2024-03-01

5072 Mispacking of the F87 sidechain drives aggregation-promoting conformational fluctuations in the subunit interfaces of the transthyretin tetramer

Sun, X.; Ferguson, J. A.; Yang, K.; Stanfield, R. L.; Dyson, J.; Wright, P.

10.1101/2024.02.26.582172 — biophysics — Posted on 2024-03-01

5073 N-formylation modifies membrane damage associated to PSMα3 interfacial fibrillation

Bonnecaze, L.; Jumel, K.; Vial, A.; Khemtemourian, L.; Feuillie, C.; Molinari, M.; Lecomte, S.; Mathelie-Guinlet, M.

10.1101/2024.02.27.582255 — biophysics — Posted on 2024-03-01

5074 Evaluating computational efforts and physiological resolution of mathematical models of cardiac tissue

Jaeger, K. H.; Trotter, J. D.; Cai, X.; Arevalo, H.; Tveito, A.

10.1101/2024.02.27.582288 — biophysics — Posted on 2024-03-01

5075 Non-Electrostatic Basis for an Artificial Metalloenzyme Catalysis

Mukherjee, A.; Roy, S.

10.1101/2024.02.27.582238 — biophysics — Posted on 2024-03-01

5076 Diverse cell death signature based subtypes predict the prognosis and immune characteristics within glioma

Wang, L.; Song, J.; Xu, J.; Qin, Y.; Li, J.; Sun, Y.; Jin, H.; Chen, J.; Wang, Z.

10.1101/2024.02.29.582704 — bioinformatics — Posted on 2024-03-01

5077 Resistance Gene Association and Inference Network (ReGAIN): A Bioinformatics Pipeline for Assessing Probabilistic Co-Occurrence Between Resistance Genes in Bacterial Pathogens

Bring Horvath, E. R.; Stein, M. G.; Mulvey, M. A.; Hernandez, E. J.; Winter, J. M.

10.1101/2024.02.26.582197 — bioinformatics — Posted on 2024-03-01

5078 racoon_clip - a complete pipeline for single-nucleotide analyses of iCLIP and eCLIP data

Klostermann, M.; Zarnack, K.

10.1101/2024.02.27.582237 — bioinformatics — Posted on 2024-03-01

5079 Exploring a large cancer cell line RNA-sequencing dataset with k-mers

Bessiere, C.; Xue, H.; Guibert, B.; Boureux, A.; Ruffle, F.; Viot, J.; Chikhi, R.; Salson, M.; Marchet, C.; Commes, T.; Gautheret, D.

10.1101/2024.02.27.581927 — bioinformatics — Posted on 2024-03-01

5080 mulea - an R package for enrichment analysis using multiple ontologies and empirical FDR correction

Turek, C.; Olbei, M.; Stirling, T.; Fekete, G.; Tasnadi, E.; Gul, L.; Bohar, B.; Papp, B.; Jurkowski, W.; Ari, E.

10.1101/2024.02.28.582444 — bioinformatics — Posted on 2024-03-01

5081 Transposable Elements and piRNAs interaction prediction with Predictive Bi-Clustering Trees

Freire Oliveira, H.; Dos Santos, R. A. C.; Cerri, R.

10.1101/2024.02.28.582449 — bioinformatics — Posted on 2024-03-01

5082 Benchmarking transcriptional deconvolution methods for estimating tissue- and cell type-specific extracellular vesicle abundances

Larsen, J. H.; Jensen, I. S.; Svenningsen, P.

10.1101/2024.02.27.582268 — bioinformatics — Posted on 2024-03-01

5083 Translation coupled mRNA-decay is a function of both structural and codon level characteristics

Basu, S.; Hait, S.; Kundu, S.

10.1101/2024.02.28.582446 — bioinformatics — Posted on 2024-03-01

5084 Device Design and Diagnostic Imaging of Radiopaque 3D Printed Tissue Engineering Scaffolds

Delemeester, M.; Pawelec, K.; Hix, J.; Siegenthaler, J.; Lissy, M.; Douek, P.; Hoummeau, A.; Si-Mohamed, S.; Shapiro, E.

10.1101/2024.02.26.582070 — bioengineering — Posted on 2024-03-01

5085 Dynamic Mode Decomposition for Transient Cavitation Bubbles Imaging in Pulsed High Intensity Focused Ultrasound Therapy

Song, M.; Sapozhnikov, O. A.; Khokhlova, V. A.; Khokhlova, T. D.

10.1101/2024.02.26.582222 — bioengineering — Posted on 2024-03-01

5086 Quantification of NAD+ T1 and T2 relaxation times using downfield 1H MRS at 7 T in human brain in vivo

Swago, S.; Wilson, N. E.; Elliott, M. A.; Nanga, R. P. R.; Reddy, R.; Witschey, W. R.

10.1101/2024.02.27.582276 — bioengineering — Posted on 2024-03-01

5087 A Silicon Diode based Optoelectronic Interface for Bidirectional Neural Modulation

Sheng, X.

10.1101/2024.02.27.582240 — bioengineering — Posted on 2024-03-01

5088 Measuring the orientation of segmented Deep Brain Stimulation leads using electroencephalography

Bince Jacob, A.; Krueger, M. T.; Akram, H.; Aristovich, K.; Litvak, V.

10.1101/2024.02.27.582287 — bioengineering — Posted on 2024-03-01

5089 Structural basis of Fusobacterium nucleatum adhesin Fap2 interaction with receptors on cancer and immune cells

Schöpf, F.; Marongiu, G. L.; Milaj, K.; Sprink, T.; Kikhney, J.; Moter, A.; Roderer, D.

10.1101/2024.02.28.582045 — biochemistry — Posted on 2024-03-01

5090 Deep learning modeling of ribosome profiling reveals regulatory underpinnings of translatome and interprets disease variants

He, J.; Xiong, L.; Shi, S.; Li, C.; Chen, K.; Fang, Q.; Nan, J.; Ding, K.; Li, J.; Mao, Y.; Boix, C. A.; Hu, X.; Kellis, M.; Xiong, X.

10.1101/2024.02.26.582217 — genomics — Posted on 2024-03-01

5091 Assessing methylation detection for primary human tissue using Nanopore sequencing

Genner, R.; Akeson, S.; Meredith, M.; Jerez, P. A.; Malik, L.; Baker, B.; Miano-Burkhardt, A.; Team, C.-l.-r.; Paten, B.; Billingsley, K. J.; Blauwendraat, C.; Jain, M.

10.1101/2024.02.29.581569 — genomics — Posted on 2024-03-01

5092 Rare and Common Variants Associated with Alcohol Consumption Identify a Conserved Molecular Network

Leger, B. S.; Meredith, J. J.; Ideker, T.; Sanchez-Roige, S.; Palmer, A. A.

10.1101/2024.02.26.582195 — genetics — Posted on 2024-03-01

5093 Khdc3 Regulates Metabolism Across Generations in a DNA-Independent Manner

Senaldi, L.; Hassan, N.; Cullen, S.; Balaji, U.; Trigg, N.; Gu, J.; Finkelstein, H.; Phillips, K.; Conine, C.; Smith-Raska, M.

10.1101/2024.02.27.582278 — genetics — Posted on 2024-03-01

5094 Improved prediction of site-rates from structure with averaging across homologs

Norn, C.; Oliveira, F.; Andre, I.

10.1101/2024.02.27.582061 — evolutionary biology — Posted on 2024-03-01

5095 Premeiotic endoreplication is the mechanism of obligate parthenogenesis in rock lizards of the genus Darevskia

Dedukh, D.; Altmanova, M.; Petrosyan, R.; Arakelyan, M.; Galoyan, E.; Kratochvil, L.

10.1101/2024.02.27.582286 — evolutionary biology — Posted on 2024-03-01

5096 Factors that influence the caste ratio in a bacterial division of labour

Avitia Dominguez, L.; Yu, Z.; Chopra, V.; Merks, R. M. H.; van Dijk, B.; Rozen, D.

10.1101/2024.02.28.582448 — evolutionary biology — Posted on 2024-03-01

5097 Both environmental conditions and intra- and interspecific interactions influence the movements of a marine predator

Mourier, J.; Soria, M.; Silk, M.; Demichelis, A.; Dagorn, L.; Hattab, T.

10.1101/2024.02.26.582077 — ecology — Posted on 2024-03-01

5098 Phylogeny, morphology, virulence, ecology, and host range of Ordospora pajunii (Ordosporidae), a microsporidian symbiont of Daphnia spp.

Dziuba, M. K.; McIntire, K. M.; Seto, K.; Davenport, E. S.; Rogalski, M. A.; Gowler, C. D.; Baird, E.; Vaandrager, M.; Huerta, C.; Jaye, R.; Corcoran, F. E.; Withrow, A.; Ahrendt, S.; Salamov, A.; Nolan, M.; Tejomurthula, S.; Barry, K.; Grigoriev, I.; James, T.; Duffy, M. A.

10.1101/2023.04.21.537887 — ecology — Posted on 2024-03-01

5099 How to quantify developmental synchrony in malaria parasites

Greischar, M. A.; Savill, N. J.; Reece, S. E.; Mideo, N.

10.1101/2024.02.27.582296 — ecology — Posted on 2024-03-01

5100 Senescence of endplate osteoclasts induces sensory innervation and spinal pain

Pan, D.; Benkato, K. G.; Han, X.; Zheng, J.; Kumar, V.; Wan, M.; Zheng, J.; Cao, X.

10.1101/2023.10.26.564218 — cell biology — Posted on 2024-03-01

5101 FHOD-1/profilin-mediated actin assembly protect sarcomeres against contraction-induced deformation in C. elegans

Kimmich, M. J.; Sundaramurthy, S.; Geary, M. A.; Lesanpezeshki, L.; Yingling, C. V.; Vanapalli, S. A.; Littlefield, R. S.; Pruyne, D.

10.1101/2024.02.29.582848 — cell biology — Posted on 2024-03-01

5102 Systematic mutagenesis assay promotes comprehension of the strand-bias laws for mutations induced by oxidative DNA damage

Kawai, H.; Ebi, S.; Sugihara, R.; Fujiwara, C.; Fujikawa, Y.; Kimura, S.; Kamiya, H.

10.1101/2024.02.29.581290 — cell biology — Posted on 2024-03-01

5103 Insight into the regulatory mechanism of the MFS transporter, SCO4121 by the MarR regulator, SCO4122

Nag, A.; Sharma, S.; Rani, P. S.; Mehra, S.

10.1101/2024.02.28.577416 — molecular biology — Posted on 2024-03-01

5104 HDAC1 controls the generation and maintenance of effector-like CD8+ T cells during chronic viral infection

Rica, R.; Waldherr, M.; Schülein, M.; Miyakoda, E.; Sandner, L.; Stolz, V.; Waltenberger, D.; Krausgruber, T.; Bock, C.; Boucheron, N.; Ellmeier, W.; Sakaguchi, S.

10.1101/2024.02.28.580886 — immunology — Posted on 2024-03-01

5105 Dynamic role of monocytes and meningeal macrophages in bacterial meningoencephalitis

Gres, V.; Lohrmann, F.; Fuchs, V.; Pahutan Bosch, L. F.; Lösslein, A. K.; Neuber, J.; Mansoori Moghadam, Z.; Martins, T.; Baasch, S.; Henschel, J.; Freudenhammer, M.; Prinz, M.; Kierdorf, K.; Kolter, J.; Erny, D.; Henneke, P.

10.1101/2024.02.27.582183 — immunology — Posted on 2024-03-01

5106 Investigating RNA splicing as a source of cellular diversity using a binomial mixture model

Isaev, K.; Knowles, D. A.

10.1101/2023.10.17.562774 — systems biology — Posted on 2024-03-01

5107 A general strategy to engineer high-performance mammalian Whole-Cell Biosensors

Mallozzi, A.; Fusco, V.; Ragazzini, F.; Praznik, A.; Jerala, R.; di Bernardo, D.

10.1101/2024.02.28.582526 — synthetic biology — Posted on 2024-03-01

5108 Chitosan induces salicylic acid local and systemically in banana plants and reduces colonization by the pathogen Fusarium oxysporum f. sp. cubense TR4

Lopez-Moya, F.; Zorrilla-Fontanesi, J.; Lozano-Soria, A.; Fernandez-De Larrinoa Ganado, N.; Moreno-Gonzalez, C. M.; Hernandez, A.; Torres, A.; Gonzalez-Silvera, D.; Gunse, B.; Lopez-Jimenez, J. A.; Lopez-Llorca, L. V.

10.1101/2024.02.27.582266 — plant biology — Posted on 2024-03-01

5109 Chromosome-scale pearl millet genomes reveal a CARLACTONOIC ACID METHYL TRANSFERASE as key determinant of strigolactone pattern and Striga susceptibility

Kuijer, H. N.; Wang, J. Y.; Bougouffa, S.; Abrouk, M.; Jamil, M.; Incitti, R.; Alam, I.; Balakrishna, A.; Alvarez, D.; Votta, C.; Chen, G.-T.; Martinez, C.; Zuccolo, A.; Berqdar, L.; Sioud, S.; Fiorilli, V. N.; de Lera, A. R.; Lanfranco, L.; Gojobori, T.; Wing, R. A.; Krattinger, S.; Gao, X.; Al-Babili, S.

10.1101/2024.02.28.582441 — plant biology — Posted on 2024-03-01

5110 Oolonghomobisflavans from Camellia sinensis disaggregate tau fibrils across Alzheimer's disease models

Duangjan, C.; Chang, X.; Seidler, P. M.; Curran, S. P.

10.1101/2024.02.26.582120 — physiology — Posted on 2024-03-01

5111 Prenatal Exposure to Environmentally Relevant Low Dosage Dibutyl Phthalate Reduces Placental Efficiency in CD-1 Mice

Pontifex, T.; Yang, X.; Tracy, A.; Burns, K.; Craig, Z.; Zhou, C.

10.1101/2024.02.26.582170 — physiology — Posted on 2024-03-01

5112 Hydroxysteroid 17-beta dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

Mahmood, S.; Morrice, N. Z.; Thompson, D.; Milanizadeh, S.; Wilson, S.; Whitfield, P. D.; Mcilroy, G. D.; Rochford, J. J.; Mody, N.

10.1101/2024.02.27.582262 — physiology — Posted on 2024-03-01

5113 Xylazine enhances the tranq, but not the fentanyl dope

St. Onge, C.; Canfield, J.; Ortiz, A.; Sprague, J.; Banks, M.

10.1101/2024.02.26.582112 — pharmacology and toxicology — Posted on 2024-03-01

5114 Bio-guided isolation of a new sesquiterpene from Artemisia cina with anthelmintic activity against Haemonchus contortus L3 infective larvae

Arango-De la Pava, L. D.; Gonzalez-Cortazar, M.; Zamilpa, A.; Cuellar-Ordaz, J. A.; de la Cruz-Cruz, H. A.; Higuera-Piedrahita, R. I.; Lopez-Arellano, R.

10.1101/2024.02.26.582230 — pharmacology and toxicology — Posted on 2024-03-01

5115 SIEGA the integrated genomic surveillance system of Andalusia, a One Health regional resource connected with the clinic

Casimiro-Soriguer, C. S.; Perez-Florido, J.; Robles, E. A.; Lara, M.; Aguado, A.; Iglesias, M. A. R.; Lepe, J. A.; Garcia, F.; Perez-Alegre, M.; Andujar, E.; Jimenez, V. E.; Camino, L. P.; Lorusso, N.; Ameyugo, U.; Vazquez, I. M.; Lozano, C. M.; Chaves, J. A.; Dopazo, J.

10.1101/2024.02.29.582716 — microbiology — Posted on 2024-03-01

5116 Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria

Beauchemin, E. T.; Hunter, C.; Maurice, C. F.

10.1101/2024.02.01.578403 — microbiology — Posted on 2024-03-01

5117 The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness

Zeng, H.; Zhu, X.; Wu, Y.; Li, Y.; Zhou, X.; Watzlawik, J.; Chen, Y. M.; Raybuck, A.; Billadeau, D.; Shapiro, V.; Springer, W.; Sun, J.; Boothby, M. R.

10.1101/2024.02.26.582122 — immunology — Posted on 2024-03-01

5118 RAG1 and RAG2 Non-core Regions Are Implicated in Leukemogenesis and Off-target V(D)J Recombination in BCR-ABL1-driven B-cell Lineage Lym-phoblastic Leukemia

Yu, X.; Zhou, W.; Chen, X.; He, S.; Qin, M.; Yuan, M.; Wang, Y.; Odhiambo, W. o.; Miao, Y.; Ji, Y.

10.1101/2023.09.29.560132 — immunology — Posted on 2024-03-01

5119 HuD (ELAVL4) gain-of-function impairs neuromuscular junctions and induces apoptosis in in vitro and in vivo models of amyotrophic lateral sclerosis

Silvestri, B.; Mochi, M.; Mawrie, D.; de Turris, V.; Colantoni, A.; Borhy, B.; Medici, M.; Anderson, E. N.; Garone, M. G.; Zammerilla, C. P.; Pandey, U. B.; Rosa, A.

10.1101/2023.08.22.554258 — neuroscience — Posted on 2024-03-01

5120 The effect of enriched versus inadequate housing conditions on eucalyptus smoke-induced cardiovascular dysfunction in mice

Harmon, M.; Fiamingo, M.; Toler, S.; Lee, K.; Kim, Y.; Martin, B.; Gilmour, M. I.; Farraj, A.; Hazari, M.

10.1101/2024.02.26.582161 — pharmacology and toxicology — Posted on 2024-03-01

5121 Modular, Vascularized Hypertrophic Cartilage Constructsfor Bone Tissue Engineering Applications

Schott, N.; Kaur, G.; Coleman, R.; Stegemann, J.

10.1101/2024.02.26.582166 — bioengineering — Posted on 2024-03-01

5122 A Micro-scale Humanized Ventilator-on-a-Chip to Examine the Injurious Effects of Mechanical Ventilation

Gabela-Zuniga, B.; Shukla, V. C.; Bobba, C.; Higuita-Castro, N.; Powell, H. M.; Englert, J. A.; Ghadiali, S. N.

10.1101/2024.02.26.582200 — bioengineering — Posted on 2024-03-01

5123 Near-perfect precise on-target editing of human hematopoietic stem and progenitor cells

Cloarec-Ung, F.-M.; Beaulieu, J.; Suthananthan, A.; Lehnertz, B.; Sauvageau, G.; Sheppard, H. M.; Knapp, D. J.

10.1101/2023.05.26.542436 — bioengineering — Posted on 2024-03-01

5124 A note on predator-prey dynamics in radiocarbon datasets

Marom, N.; Wolkowski, U.

10.1101/2023.11.12.566733 — ecology — Posted on 2024-03-01

5125 Gut microbes of the cecum versus the colon drive more severe lethality and multi-organ damage

Xu, K.; Tan, J.; Lin, D.; Chu, Y.; Zhou, L.; Zhang, J.; Lu, Y.

10.1101/2024.02.26.582076 — immunology — Posted on 2024-03-01

5126 CAR-engineered lymphocyte persistence is governed by a FAS ligand/FAS auto-regulatory circuit

Yi, F.; Cohen, T.; Zimmerman, N.; Dundar, F. A.; Zumbo, P.; Eltilib, R.; Brophy, E. J.; Arkin, H.; Feucht, J.; Gormally, M. V.; Hackett, C. S.; Kropp, K. N.; Etxeberria, I.; Chandran, S. S.; Park, J. H.; Hsu, K. C.; Sadelain, M.; Betel, D.; Klebanoff, C. A.

10.1101/2024.02.26.582108 — immunology — Posted on 2024-03-01

5127 Genetic regulation and targeted reversal of lysosomal dysfunction and inflammatory sterol metabolism in pulmonary arterial hypertension

Harvey, L. D.; Alotaibi, M.; Kim, H.-J. J.; Tai, Y.-Y.; Tang, Y.; Sun, W.; El Khoury, W.; Woodcock, C.-S. C.; Aaraj, Y. A.; St. Croix, C. M.; Stolz, D. B.; Lee, J.; Cheng, M. H.; Schwantes-An, T.-H.; Desai, A. A.; Pauciulo, M. W.; Nichols, W. C.; Webb, A.; Lafyatis, R.; Nouraie, M.; Wu, H.; McDonald, J. G.; Chauvet, C.; Cheng, S.; Bahar, I.; Bertero, T.; Benza, R. L.; Jain, M.; Chan, S. Y.

10.1101/2024.02.26.582142 — physiology — Posted on 2024-03-01

5128 Oarfish: Enhanced probabilistic modeling leads to improved accuracy in long read transcriptome quantification

Jousheghani, Z. Z.; Patro, R.

10.1101/2024.02.28.582591 — bioinformatics — Posted on 2024-03-01

5129 Azadirachta indica: derived, red-emitting, carbon nanoparticles for cellular bioimaging and potential therapeutics

Gandhi, S.; Jain, S.; Bhatia, D. D.; Yadav, P.

10.1101/2024.02.26.582094 — bioengineering — Posted on 2024-03-01

5130 Optimal inventorying and monitoring of taxonomic, phylogenetic and functional diversity

Cardoso, P.; Arnedo, M. A.; Macias-Hernandez, N.; Carvalho, W. D.; Carvalho, J. C.; Hilario, R.

10.1101/060400 — ecology — Posted on 2024-03-01

5131 FLYNC: A Machine Learning-Driven Framework for Discovering Long Non-Coding RNAs in Drosophila melanogaster

dos Santos, R. F.; Baptista, T.; Marques, G. S.; Homem, C. C. F.

10.1101/2024.02.27.582305 — genomics — Posted on 2024-03-01

5132 N-terminal targeting sequences and coding sequences act in concert to determine the localization and trafficking pathway of apicoplast proteins in Toxoplasma gondii.

Anjum, S.; Prasad, A.; Mastud, P.; Patankar, S.

10.1101/2023.06.20.545694 — molecular biology — Posted on 2024-03-01

5133 Protective effect and molecular mechanisms of human non-neutralizing cross-reactive spike antibodies elicited by SARS-CoV-2 mRNA vaccination

Clark, J.; Hoxie, I.; Adelsberg, D.; Sapse, I.; Andreata-Santos, R.; Yong, J.; Amanat, F.; Tcheou, J.; Raskin, A.; Singh, G.; Gonzalez-Dominguez, I.; Edgar, J.; Bournazos, S.; Sun, W.; Carreno, J. M.; Simon, V.; Ellebedy, A.; Bajic, G.; Krammer, F.

10.1101/2024.02.28.582613 — immunology — Posted on 2024-03-01

5134 Visual-spatial dynamics drive adaptive social learning in immersive environments

Wu, C. M.; Deffner, D.; Kahl, B.; Meder, B.; Ho, M. H.; Kurvers, R. H.

10.1101/2023.06.28.546887 — animal behavior and cognition — Posted on 2024-03-01

5135 Advancing single cell technology: iSCseq drives living subcellular transcriptomic profiling in osteoimmune diversity

Okada, H.; Terui, Y.; Seki, M.; Terashima, A.; Tani, S.; Motooka, D.; Kanazawa, S.; Hosonuma, M.; Miyahara, J.; Makabe, K.; Omata, Y.; Onodera, S.; Yano, F.; Kajiya, H.; Gori, F.; Saito, T.; Okabe, K.; Suzuki, Y.; Baron, R.; Chung, U.-i.; Tanaka, S.; Hojo, H.

10.1101/2022.09.05.506360 — genomics — Posted on 2024-03-01

5136 Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot

Aramburu, O.; Pardo, B. G.; Rodriguez-Villamayor, P.; Blanco Hortas, A.; Lamas, J.; Dewari, P. S.; Perojil, D.; Boudinot, P.; Macqueen, D. J.; Bouza, C.; Martinez, P.

10.1101/2024.02.15.580452 — genomics — Posted on 2024-03-01

5137 Context dependent perturbation of allelic expression imbalance reveals novel candidate therapeutic targets for metabolic diseases

Moon, S.; Park, S.-Y.

10.1101/2023.11.06.565672 — genomics — Posted on 2024-03-01

5138 eSVD-DE: Cohort-wide differential expression in single-cell RNA-seq data using exponential-family embeddings

Lin, K.; Qiu, Y.; Roeder, K.

10.1101/2023.11.22.568369 — genomics — Posted on 2024-03-01

5139 Exploring the ageing methylome in the model insect,Nasonia vitripennis

Brink, K.; Thomas, C.; Jones, A.; Chan, T. W.; Mallon, E. B.

10.1101/2023.02.14.528436 — genomics — Posted on 2024-03-01

5140 Target-specific requirements for RNA interference can arise through restricted RNA amplification despite the lack of specialized pathways

Knudsen-Palmer, D. R.; Raman, P.; Ettefa, F.; DeRavin, L.; Jose, A. M.

10.1101/2023.02.07.527351 — genetics — Posted on 2024-03-01

5141 Characterization of Z chromosomal inversion and lineage-specific sweeps reveal widespread local adaptation in Helicoverpa armigera

Ke, F.

10.1101/2023.09.28.560065 — evolutionary biology — Posted on 2024-03-01

5142 Altered drug metabolism and increased susceptibility to fatty liver disease in myotonic dystrophy

Dewald, Z. L.; Gupta, A.; Chembazhi, U. V.; Kalsotra, A. L.

10.1101/2021.04.06.438688 — molecular biology — Posted on 2024-03-01

5143 Model Agnostic Semi-Supervised Meta-Learning Elucidates Understudied Out-of-distribution Molecular Interactions

Wu, Y.; Xie, L.; Liu, Y.; Xie, L.

10.1101/2023.05.17.541172 — systems biology — Posted on 2024-03-01

5144 Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice

Fischer, A. A. M.; Robertson, H. B.; Kong, D.; Grimm, M. M.; Grether, J.; Groth, J.; Baltes, C.; Fliegauf, M.; Lautenschlaeger, F.; Grimbacher, B.; Ye, H.; Helms, V.; Weber, W.

10.1101/2023.10.16.562453 — synthetic biology — Posted on 2024-03-01

5145 The landscape of biomedical research

Gonzalez-Marquez, R.; Schmidt, L.; Schmidt, B. M.; Berens, P.; Kobak, D.

10.1101/2023.04.10.536208 — scientific communication and education — Posted on 2024-03-01

5146 Evaluation of common in vitro assays for the prediction of oral bioavailability and hepatic metabolic clearance in humans

Fagerholm, U.

10.1101/2024.02.25.581937 — pharmacology and toxicology — Posted on 2024-03-01

5147 Cancer associated fibroblasts mitigate the efficacy of the combination treatment of chemotherapy and BCL-xL targeting in triple negative breast cancer cells

Nocquet, L.; Roul, J.; Duarte, L.; Campone, M.; Juin, P. P.; Souaze, F.

10.1101/2023.09.26.559287 — cancer biology — Posted on 2024-03-01

5148 Cancer immunotherapy responses persist after lymph node resection

Zhou, H.; Baish, J. W.; O'Melia, M. J.; Darragh, L. B.; Specht, E.; Czapla, J.; Lei, P.-j.; Menzel, L.; Rajotte, J. J.; Nikmaneshi, M. R.; Razavi, M. S.; Vander Heiden, M. G.; Ubellacker, J. M.; Munn, L. L.; Boland, G. M.; Cohen, S.; Karam, S. D.; Padera, T. P.

10.1101/2023.09.19.558262 — cancer biology — Posted on 2024-03-01

5149 NSD2 is a requisite subunit of the AR/FOXA1 neo-enhanceosome in promoting prostate tumorigenesis

Parolia, A.; Eyunni, S.; Verma, B. K.; Young, E.; Liu, L.; George, J.; Aras, S.; Das, C. K.; Mannan, R.; ur Rasool, R.; Luo, J.; Carson, S. E.; Mitchell-Velasquez, E.; Liu, Y.; Xiao, L.; Gajjala, P. R.; Jaber, M.; He, T.; Qiao, Y.; Pang, M.; Zhang, Y.; Alhusayan, M.; Cao, X.; Tavana, O.; Hou, C.; Wang, Z.; Ding, K.; Chinnaiyan, A. M.; Asangani, I. A.

10.1101/2024.02.22.581560 — cancer biology — Posted on 2024-03-01

5150 ConBoTNet: supervised contrastive learning enhances MHC-II peptide binding affinity prediction

Shen, L.-C.; Yan, L.; Liu, Z.; Zhang, Y.; Wang, Z.; Guo, Y.; Rossjohn, J.; Song, J.; Yu, D.-J.

10.1101/2023.12.21.572942 — bioinformatics — Posted on 2024-03-01

5151 FLOP: Tasks for Fitness Landscapes Of Protein wildtypes

Groth, P. M.; Michael, R.; Salomon, J.; Tian, P.; Boomsma, W.

10.1101/2023.06.21.545880 — bioinformatics — Posted on 2024-03-01

5152 Interactive visualisation of raw nanopore signal data with Squigualiser

Samarakoon, H.; Liyanage, K.; Ferguson, J.; Parameswaran, S.; Gamaarachchi, H.; Deveson, I.

10.1101/2024.02.19.581111 — bioinformatics — Posted on 2024-03-01

5153 The De Bruijn Graph Sequence Mapping Problem with Changes in the Graph

B. Rocha, L.; Adi, S. S.; Araujo, E.

10.1101/2024.02.15.580401 — bioinformatics — Posted on 2024-03-01

5154 Engineering an Escherichia coli strain for production of long single-stranded DNA

Shen, K.; Flood, J. J.; Zhang, Z.; Ha, A.; Shy, B. R.; Dueber, J. E.; Douglas, S. M.

10.1101/2024.02.27.582394 — bioengineering — Posted on 2024-03-01

5155 Microwave assisted acidification for green hydrogen and organic acids production

Barth, M.; Werner, M.; Otto, P.; Richwien, B.; Bahramsari, S.; Krause, M.; Schwan, B.; Abendroth, C.

10.1101/2023.11.18.567651 — bioengineering — Posted on 2024-03-01

5156 ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

Bartolome, A.; Heiby, J. C.; Di Fraia, D.; Heinze, I.; Knaudt, H.; Spaeth, E.; Omrani, O.; Minetti, A.; Hofmann, M.; Kirkpatrick, J. M.; Dau, T.; Ori, A.

10.1101/2022.08.09.503299 — biochemistry — Posted on 2024-03-01

5157 Eco-evolutionary dynamics of partially migratory metapopulations in spatially and seasonally varying environments

Haaland, T. R.; Payo-Payo, A.; Acker, P.; Fortuna, R. R.; Burthe, S.; Ratikainen, I. I.; Daunt, F.; Reid, J. M.

10.1101/2023.11.28.568986 — evolutionary biology — Posted on 2024-03-01

5158 Metabolic trade-offs can reverse the resource-diversityrelationship

Miller, Z. R.; O'Dwyer, J. P.

10.1101/2023.08.28.555123 — ecology — Posted on 2024-03-01

5159 CD44 facilitates adhesive interactions in airineme-mediated intercellular signaling

Bowman, R. L.; Kim, J.; Eom, D. S.

10.1101/2024.02.27.582398 — developmental biology — Posted on 2024-03-01

5160 miR-203 controls developmental timing and early fate restriction during preimplantation embryogenesis

Gonzalez-Martinez, J.; Sanchez-Belmonte, A.; Ayala, E.; Garcia, A.; Nogueira, E.; Munoz, J.; Melati, A.; Gimenez, D.; Losada, A.; Ortega, S.; Malumbres, M.

10.1101/2024.02.06.579214 — developmental biology — Posted on 2024-03-01

5161 DVL1 variants and C-terminal deletions have differential effects on craniofacial development and WNT signaling

Tophkhane, S. S.; Gignac, S. J.; Fu, K.; Verheyen, E. M.; Richman, J.

10.1101/2024.02.28.582602 — developmental biology — Posted on 2024-03-01

5162 A chemically-induced attenuated strain of Candida albicans generates robust protective immune responses and prevents systemic candidiasis development

Bose, S.; Sahu, S. R.; Dutta, A.; Acharya, N.

10.1101/2023.11.03.565495 — microbiology — Posted on 2024-03-01

5163 INO80 regulates chromatin accessibility to facilitate suppression of sex-linked gene expression during mouse spermatogenesis

Chakraborty, P.; Magnuson, T.

10.1101/2023.01.04.522761 — developmental biology — Posted on 2024-03-01

5164 The evolution of antimicrobial peptide resistance in Pseudomonas aeruginosa is severely constrained by random peptide mixtures

Antunes, B.; Zanchi, C.; Johnston, P. R.; Maron, B.; Witzany, C.; Regoes, R. R.; Hayouka, Z.; Rolff, J.

10.1101/2024.02.22.581582 — microbiology — Posted on 2024-03-01

5165 Human MX1 orchestrates the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

McKellar, J.; Garcia de Gracia, F.; Aube, C.; Chaves Valadao, A. L.; Tauziet, M.; Arnaud-Arnould, M.; Rebendenne, A.; Neyret, A.; Labaronne, E.; Ricci, E. P.; Delaval, B.; Gaudin, R.; Naffakh, N.; Gallois-Montbrun, S.; Moncorge, O.; Goujon, C.

10.1101/2024.02.22.581565 — microbiology — Posted on 2024-03-01

5166 The ubiquitin-conjugating enzyme UBE2D/eff maintains a youthful proteome and ensures protein quality control during aging

Hunt, L. C.; Nyamkondiwa, K.; Stephan, A.; Jiao, J.; Kavdia, K.; Pagala, V.; Peng, J.; Demontis, F.

10.1101/2023.12.12.571303 — cell biology — Posted on 2024-03-01

5167 Natural variation of immune epitopes reveals intrabacterial antagonism

Stevens, D. M.; Moreno-Perez, A.; Weisberg, A. J.; Ramsing, C.; Fliegmann, J.; Zhang, N.; Madrigal, M.; Martin, G.; Steinbrenner, A.; Felix, G.; Coaker, G.

10.1101/2023.09.21.558511 — microbiology — Posted on 2024-03-01

5168 E. coli leverages growth arrest to remodel its proteome upon entry into starvation

Gervais, T.; Kscheschinski, B.; Mell, M.; Goepfert, N.; van Nimwegen, E.; Julou, T.

10.1101/2024.02.29.582700 — microbiology — Posted on 2024-03-01

5169 Enterohemorrhagic Escherichia coli (EHEC) Disrupts Intestinal Barrier Integrity in Translational Canine Stem Cell-Derived Monolayers

Nagao, I.; Kawasaki, M.; Goyama, T.; Kim, H. J.; Call, D. R.; Ambrosini, Y.

10.1101/2024.02.27.582360 — microbiology — Posted on 2024-03-01

5170 Parvalbumin Interneuron Impairment Leads to Synaptic Transmission Deficits and Seizures in SCN8A Epileptic Encephalopathy

Miralles, R. M.; Boscia, A. R.; Kittur, S.; Vundela, S. R.; Wengert, E. R.; Patel, M. K.

10.1101/2024.02.09.579511 — neuroscience — Posted on 2024-03-01

5171 Speech prosody enhances the neural processing of syntax

Degano, G.; Donhauser, P.; Gwilliams, L.; Merlo, P.; Golestani, N.

10.1101/2023.07.03.547482 — neuroscience — Posted on 2024-03-01

5172 Noisy neuronal populations effectively encode sound localization in the dorsal inferior colliculus of awake mice

Boffi, J. C.; Bathellier, B.; Asari, H.; Prevedel, R.

10.1101/2022.08.19.504510 — neuroscience — Posted on 2024-03-01

5173 Minimum Effective Dose of Clemastine in a Mouse Model of Preterm White Matter Injury

Odell, E. P.; Jabassini, N.; Schniedewind, B.; Pease-Raissi, S. E.; Frymoyer, A.; Christians, U.; Green, A. J.; Chan, J. R.; Ostrem, B. E. L.

10.1101/2024.02.08.578953 — neuroscience — Posted on 2024-03-01

5174 Identifying regulators of associative learning using a protein-labelling approach in C. elegans

Rahmani, A.; McMillen, A.; Allen, E.; Ansaar, R.; Poljak, A.; Chew, Y. L.

10.1101/2024.02.19.580416 — neuroscience — Posted on 2024-03-01

5175 Dnmt3a1 regulates hippocampus-dependent memory via the downstream target Nrp1

Kupke, J.; Klimmt, J.; Mudlaff, F.; Schwab, M.; Lutsik, P.; Plass, C.; Sticht, C.; Oliveira, A. M. M.

10.1101/2023.05.22.541739 — neuroscience — Posted on 2024-03-01

5176 Sex Differences in Dopamine Release in Nucleus Accumbens and Dorsal Striatum Determined by Chronic Fast Scan Cyclic Voltammetry: Effects of social housing and repeated stimulation

Gonzalez, I. L.; Turner, C. A.; Patel, P. R.; Leonardo, N. B.; Luma, B. D.; Richie, J. M.; Cai, D.; Chestek, C. A.; Becker, J. B.

10.1101/2023.08.14.553278 — neuroscience — Posted on 2024-03-01

5177 Method to quickly map multifocal Pupillary Response Fields (mPRF) using Frequency Tagging

Lorenceau, J.

10.1101/2023.06.28.546061 — neuroscience — Posted on 2024-03-01

5178 Lifespan reference curves for harmonizing multi-site regional brain white matter metrics from diffusion MRI

Zhu, A. H.; Nir, T. M.; Javid, S.; Villalon-Reina, J. E.; Rodrigue, A. L.; Strike, L. T.; de Zubicaray, G. I.; McMahon, K. L.; Wright, M. J.; Medland, S. E.; Blangero, J. E.; Glahn, D. C.; Kochunov, P.; Haberg, A. K.; Thompson, P. M.; Jahanshad, N.

10.1101/2024.02.22.581646 — neuroscience — Posted on 2024-03-01

5179 Neurogenesis and neuronal migration in hypothalamic vasopressinergic magnocellular nuclei of the adult rat

Zhang, L.; Zetter, M. A.; Hernandez, V. S.; Krabichler, Q.; Grinevich, V.

10.1101/2023.12.10.570983 — neuroscience — Posted on 2024-03-01

5180 Synchronized photoactivation of T4K rhodopsin causes a chromophore-dependent retinal degeneration that is moderated by interaction with phototransduction cascade components.

Tam`, B. M.; Burns, P. L.; Chiu, C. N.; Moritz, O. L.

10.1101/2024.02.27.582380 — neuroscience — Posted on 2024-03-01

5181 Diffusion MRS tracks distinct trajectories of neuronal development in the cerebellum and thalamus of rat neonates.

Ligneul, C.; Qiu, L.; Clarke, W. T.; Jbabdi, S.; Palombo, M.; Lerch, J.

10.1101/2023.10.16.562599 — neuroscience — Posted on 2024-03-01

5182 Medial accumbens shell spiny projection neurons encode relative reward preference

Pedersen, C. E.; Gowrishankar, R.; Piantadosi, S. C.; Castro, D. C.; Hjort, M. M.; Zhou, Z. C.; Kan, S. A.; Murphy, P. J.; O'Neill, P. R.; Bruchas, M.

10.1101/2022.09.18.508426 — neuroscience — Posted on 2024-03-01

5183 Enhanced generalization and specialization of brain representations of semantic knowledge in healthy aging

Margolles, P.; Soto, D.

10.1101/2023.08.08.552519 — neuroscience — Posted on 2024-03-01

5184 Architecture and flexibility of native kinetochores revealed by structural studies utilizing a thermophilic yeast

Barrero, D. J.; Wijeratne, S. S.; Zhao, X.; Cunningham, G. F.; Yan, R.; Nelson, C. R.; Arimura, Y.; Funabiki, H.; Asbury, C. L.; Yu, Z.; Subramanian, R.; Biggins, S.

10.1101/2024.02.28.582571 — biophysics — Posted on 2024-03-01

5185 Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase

Zeinert, R.; Zhou, F.; Franco, P. H. C.; Zoeller, J.; Lessen, H.; Aravind, L.; Langer, J.; Sodt, A. J.; Storz, G.; Matthies, D.

10.1101/2024.02.28.582502 — biophysics — Posted on 2024-03-01

5186 The Structure of ApoB100 from Human Low-density Lipoprotein

Berndsen, Z. T.; Cassidy, C. K.

10.1101/2024.02.28.582555 — biophysics — Posted on 2024-03-01

5187 Genetic architecture, spatial heterogeneity, and the coevolutionary arms race between newts and snakes

Caudill, V.; Ralph, P. L.

10.1101/2023.12.07.570693 — evolutionary biology — Posted on 2024-03-01

5188 Melanophilin mediates the association of myosin-5a with melanosome via three distinct interactions

Pan, J.; Zhou, R.; Yao, L.-L.; Zhang, J.; Zhang, N.; Cao, Q.-J.; Sun, S.; Li, X.-d.

10.1101/2023.11.01.565146 — cell biology — Posted on 2024-03-01

5189 Visual working memories are abstractions of percepts

Duan, Z.; Curtis, C. E.

10.1101/2023.12.01.569634 — neuroscience — Posted on 2024-03-01

Archive, 2024-03