1 Cytoskeleton members, MVBs and the ESCRT-III HvSNF7s are putative key players for protein sorting into protein bodies during barley endosperm development Roustan, V.; Hilscher, J.; Weidinger, M.; Reipert, S.; Shabrangy, A.; Gebert, C.; Dietrich, B.; Dermendjiev, G.; Roustan, P.-J.; Stoeger, E.; Ibl, V. 10.1101/595108 — plant biology — Posted on 2019-03-31 2 Big and Small Cerebral Asymmetries Eckert, M. A.; Vaden, K. I.; Dyslexia Data Consortium, 10.1101/269571 — neuroscience — Posted on 2019-03-31 3 Controlling Heterogeneity and Increasing Titer from Riboswitch-Regulated Bacillus subtilis Spores for Time-Delayed Protein Expression Applications Tamiev, D.; Lantz, A.; Vezeau, G.; Salis, H.; Reuel, N. F. 10.1101/592659 — microbiology — Posted on 2019-03-31 4 FGF signalling regulates enhancer activation during ear progenitor induction Tambalo, M.; Anwar, M.; Ahmed, M.; Streit, A. 10.1101/595058 — developmental biology — Posted on 2019-03-31 5 Biomolecular Contrast Agents for Optical Coherence Tomography Lu, G. J.; Chou, L.-d.; Malounda, D.; Patel, A. K.; Welsbie, D. S.; Chao, D. L.; Ramalingam, T.; Shapiro, M. G. 10.1101/595157 — bioengineering — Posted on 2019-03-31 6 Integrating case studies into graduate teaching assistant training to improve instruction in biology laboratory courses Kraft, J.; Walck-Shannon, e.; Reilly, C.; Stapleton, A. 10.1101/594853 — scientific communication and education — Posted on 2019-03-31 7 Drosophila female-specific brain neuron elicits persistent position- and direction-selective male-like social behaviors Wu, Y.; Bidaye, S.; Mahringer, D. 10.1101/594960 — neuroscience — Posted on 2019-03-31 8 Genetically diverse uropathogenic Escherichia coli adopt a common transcriptional program in patients with urinary tract infections Sintsova, A.; Frick-Cheng, A.; Smith, S.; Pirani, A.; Subashchandrabose, S.; Snitkin, E. S.; Mobley, H. 10.1101/595207 — microbiology — Posted on 2019-03-31 9 Breaking barriers: The effect of protected characteristics and their intersectionality on career transition in academics Wanelik, K. M.; Griffin, J. S.; Head, M.; Ingleby, F. C.; Lewis, Z. 10.1101/593905 — scientific communication and education — Posted on 2019-03-31 10 Xenotransplantation of Human PSC-derived Microglia Creates a Chimeric Mouse Brain Model that Recapitulates Features of Adult Human Microglia Xu, R.; Boreland, A.; Posyton, A.; Kwan, K.; Hart, R. P.; Jiang, P. 10.1101/594721 — neuroscience — Posted on 2019-03-31 11 Mini-barcodes are more suitable for large-scale species discovery in Metazoa than full-length barcodes Yeo, D.; Srivathsan, A.; Meier, R. 10.1101/594952 — evolutionary biology — Posted on 2019-03-31 12 Limiting-stress-elimination hypothesis: approach to increase savanna cowpea productivity by stress reduction Atta-Boateng, A.; Berlyn, G. 10.1101/594754 — plant biology — Posted on 2019-03-31 13 Heritability of skewed X-inactivation in female twins is tissue-specific and dependent on age Zito, A.; Davies, M. N.; Tsai, P.-C.; Roberts, S.; Nardone, S.; Bell, J. T.; Wong, C. C. Y.; Small, K. S. 10.1101/593251 — genetics — Posted on 2019-03-31 14 Predicting the Frequency of Drug Side effects Galeano, D.; Paccanaro, A. 10.1101/594465 — bioinformatics — Posted on 2019-03-31 15 Deficient stereopsis in the normal population revisited: why current clinical stereo tests may not be adequate Hess, R. F.; Dillon, R.; Ding, R.; Zhou, J. 10.1101/585976 — neuroscience — Posted on 2019-03-31 16 An organisational principle for cortical receptive fields Kristensen, D. G.; Sandberg, K. 10.1101/593608 — neuroscience — Posted on 2019-03-31 17 Early Reactivation of Emotion in ERPs to Neutral Retrieval Cues Bowen, H. J.; Fields, E. C.; Kensinger, E. A. 10.1101/594747 — neuroscience — Posted on 2019-03-31 18 Scaling of thermal tolerance with body mass and genome size in ectotherms: A comparison between water-and air-breathers Leiva, F. P.; Calosi, P.; Verberk, W. C. 10.1101/593293 — ecology — Posted on 2019-03-31 19 DNA epigenetic marks are linked to reproductive aberrations in amphipods Gorokhova, E.; Martella, G.; Motwani, N. H.; Tretyakova, N. Y.; Sundelin, B.; Motwani, H. V. 10.1101/594788 — ecology — Posted on 2019-03-31 20 An integrated one-step assay combining thermal lysis and loop-mediated isothermal DNA amplification (LAMP) in 30 min from E. coli and M. smegmatis cells on a paper substrate Naik, P.; Jaitpal, S.; Shetty, P.; Paul, D. 10.1101/594374 — bioengineering — Posted on 2019-03-31 21 Antagonistic and auxin-dependent phosphoregulation of columella PIN proteins controls lateral root gravitropic setpoint angle in Arabidopsis Roychoudhry, S.; Sageman-Furnas, K.; Wolverton, C.; Goodman, H. L.; Grones, P.; Mullen, J.; Hangarter, R.; Friml, J.; Kepinski, S. 10.1101/594838 — plant biology — Posted on 2019-03-31 22 Ambient temperature effects on stress-induced hyperthermia in Svalbard ptarmigan Nord, A.; Folkow, L. P. 10.1101/594614 — physiology — Posted on 2019-03-31 23 High-throughput single nucleotide polymorphism (SNP) discovery and validation through whole-genome resequencing of hundreds of individuals in Nile tilapia (Oreochromis niloticus) Yanez, J. M.; Yoshida, G.; Barria, A.; Palma-Vejares, R.; Travisany, D.; Diaz-Dominguez, D.; Caceres, G.; Cadiz, M. I.; Lopez, M. E.; Lhorente, J. P.; Jedlicki, A.; Soto, J.; Salas, D.; Maass, A. 10.1101/594671 — genomics — Posted on 2019-03-31 24 Catching the big picture of the Mediterranean Sea biodiversity with an end-to-end model of climate and fishing impacts Moullec, F.; Velez, L.; Verley, P.; Barrier, N.; Ulses, C.; Carbonara, P.; Esteban, A.; Follesa, C.; Gristina, M.; Jadaud, A.; Ligas, A.; Lopez Diaz, E.; Maiorano, P.; Peristeraki, P.; Spedicato, M. T.; Thasitis, I.; Valls, M.; Guilhaumon, F.; Shin, Y.-J. 10.1101/593822 — ecology — Posted on 2019-03-31 25 Stress-induced neuronal hypertrophy decreases the intrinsic excitability in stress habituation Matovic, S.; Ichiyama, A.; Igarashi, H.; Salter, E.; Wang, X. F.; Henry, M.; Vernoux, N.; Tremblay, M.-E.; Inoue, W. 10.1101/593665 — neuroscience — Posted on 2019-03-31 26 A high throughput multi-locus insecticide resistance marker panel for tracking resistance emergence and spread in Anopheles gambiae Lucas, E.; Rockett, K. A.; Lynd, A.; Essandoh, J.; Grisales, N.; Kemei, B.; Njoroge, H.; Hubbart, C.; Rippon, E. J.; Morgan, J.; Van't Hof, A.; Ochomo, E. O.; Kwiatkowski, D. P.; Weetman, D.; Donnelly, M. J. 10.1101/592279 — evolutionary biology — Posted on 2019-03-31 27 A post-translational modification signature defines changes in soluble tau correlating with oligomerization in early stage Alzheimer’s disease brain Ercan-Herbst, E.; Schoendorf, D. C.; Behrendt, A.; Klaus, B.; Gomez Ramos, B.; Weber, C.; Ehrnhoefer, D. E. 10.1101/594820 — neuroscience — Posted on 2019-03-31 28 Three new integration vectors and fluorescent proteins for use in the opportunistic human pathogen Streptococcus pneumoniae Keller, L. E.; Rueff, A.-S.; Kurushima, J.; Veening, J.-W. 10.1101/594697 — microbiology — Posted on 2019-03-31 29 Activation of a zinc metallochaperone by the alarmone ZTP Chandrangsu, P.; Huang, X.; Helmann, J. D. 10.1101/594382 — microbiology — Posted on 2019-03-31 30 A Human Tissue-Specific Transcriptomic Analysis Reveals that Ageing Hinders Cancer and Boosts Cellular Senescence Chatsirisupachai, K.; Palmer, D.; Ferreira, S.; de Magalhaes, J. P. 10.1101/595041 — cancer biology — Posted on 2019-03-31 31 AlbaTraDIS: Comparative analysis of large datasets from parallel transposon mutagenesis experiments Page, A. J.; Bastkowski, S.; Yasir, M.; Turner, K.; Le Viet, T.; Savva, G.; Webber, M.; Charles, I. G. 10.1101/593624 — bioinformatics — Posted on 2019-03-31 32 Modeling longitudinal imaging biomarkers with parametric Bayesian multi-task learning Aksman, L. M.; Scelsi, M. A.; Marquand, A. F.; Alexander, D. C.; Ourselin, S.; Altmann, A. 10.1101/593459 — neuroscience — Posted on 2019-03-31 33 A likelihood method for estimating present-day human contamination in ancient DNA samples using low-depth haploid chromosome data Moreno-Mayar, J. V.; Korneliussen, T. S.; Albrechtsen, A.; Dalal, J.; Renaud, G.; Nielsen, R.; Malaspinas, A.-S. 10.1101/594481 — genomics — Posted on 2019-03-31 34 Quantitative characterization of random partitioning in the evolution of plasmid-encoded traits Halleran, A. D.; Flores-Bautista, E.; Murray, R. M. 10.1101/594879 — evolutionary biology — Posted on 2019-03-31 35 Ferrous-glutathione coupling mediates ferroptosis and frailty in Caenorhabditis elegans Jenkins, N. L.; James, S. A.; Salim, A.; Sumardy, F.; Speed, T. P.; Conrad, M.; Richardson, D. R.; Bush, A. I.; McColl, G. 10.1101/594408 — molecular biology — Posted on 2019-03-31 36 CDK2 kinase activity is a regulator of male germ cell fate Singh, P.; Patel, R.; Palmer, N.; Grenier, J.; Paduch, D.; Kaldis, P.; Grimson, A.; Schimenti, J. 10.1101/595223 — genetics — Posted on 2019-03-31 37 Latitudinal variation in circadian rhythmicity in Nasonia vitripennis Paolucci, S.; Dalla Benetta, E.; Salis, L.; Dolezel, D.; van de Zande, L.; Beukeboom, L. 10.1101/594606 — evolutionary biology — Posted on 2019-03-31 38 Functional diversity plays a role in driving β-diversity: Or does it? Murray-Stoker, D. 10.1101/594044 — ecology — Posted on 2019-03-31 39 Estimation of cell lineage trees by maximum-likelihood phylogenetics Feng, J.; DeWitt, W. S.; McKenna, A.; Simon, N.; Willis, A. D.; Matsen, F. A. 10.1101/595215 — bioinformatics — Posted on 2019-03-31 40 Behavioural analysis of single-cell aneural ciliate, Stentor roeselii, using machine learning approaches Trinh, K. M.; Wayland, M.; Prabakaran, S. 10.1101/594796 — animal behavior and cognition — Posted on 2019-03-31 41 Neurocognitive reorganization between crystallized intelligence, fluid intelligence and white matter microstructure in two age-heterogeneous developmental cohorts Simpson-Kent, I.; Fuhrmann, D.; Bathelt, J.; Achterberg, J.; Borgeest, G. S.; Kievit, R. 10.1101/593509 — neuroscience — Posted on 2019-03-31 42 Complexity measures of the electroencephalograph capture loss and recovery of consciousness in patients anesthetized with propofol Eagleman, S. L.; Chander, D.; Reynolds, C.; Ouellette, N. T.; MacIver, M. B. 10.1101/594002 — neuroscience — Posted on 2019-03-31 43 Efficacy of antifungal drug combinations against widespread primary resistance, cross-resistance, and multidrug-resistance in Candida auris from New York Hospitals and Healthcare Facilities O'Brien, B.; Chaturvedi, S.; Chaturvedi, V. 10.1101/593848 — microbiology — Posted on 2019-03-31 44 New non-bilaterian transcriptomes provide novel insights into the evolution of coral skeletomes Conci, N.; Woerheide, G.; Vargas, S. 10.1101/594242 — evolutionary biology — Posted on 2019-03-31 45 Quantifying shape, integration, and ecology in avian pedal claws: comparing geometric morphometric and traditional metric approaches Hedrick, B.; Cordero, S.; Zanno, L.; Noto, C.; Dodson, P. 10.1101/593236 — evolutionary biology — Posted on 2019-03-31 46 A comprehensive genome-scale model for Rhodosporidium toruloides IFO0880 accounting for functional genomics and phenotypic data Dinh, H. V.; Suthers, P. F.; Chan, S. H. J.; Shen, Y.; Xiao, T.; Deewan, A.; Jagtap, S. S.; Rabinowitz, J. D.; Rao, C. V.; Zhao, H.; Maranas, C. D. 10.1101/594846 — systems biology — Posted on 2019-03-31 47 The complex genetic architecture of recombination and structural variation in wheat uncovered using a large 8-founder MAGIC population Shah, R.; Huang, B. E.; Whan, A.; Newberry, M.; Verbyla, K.; Morell, M. K.; Cavanagh, C. R. 10.1101/594317 — plant biology — Posted on 2019-03-31 48 The origins of anterograde interference in visuomotor adaptation Lerner, G.; Albert, S.; Caffaro, P. A.; Villalta, J. I.; Jacobacci, F.; Shadmehr, R.; Della-Maggiore, V. 10.1101/593996 — neuroscience — Posted on 2019-03-31 49 A three-sample test for introgression Hahn, M. W.; Hibbins, M. S. 10.1101/594333 — evolutionary biology — Posted on 2019-03-31 50 Non-uniform Crowding Enhances Transport: Relevance to Biological Environments Collins, M.; Mohajerani, F.; Ghosh, S.; Guha, R.; Lee, T.-H.; Butler, P. J.; Sen, A.; Velegol, D. 10.1101/593855 — biophysics — Posted on 2019-03-31 51 A vibrating mesh nebulizer as an alternative to the Collison 3-jet nebulizer for infectious disease aerobiology. Bowling, J. D.; O'Malley, K. J.; Klimstra, W. B.; Hartman, A. L.; Reed, D. S. 10.1101/594358 — microbiology — Posted on 2019-03-31 52 Fitness benefits of a motivated mom Westrick, S. E.; Taylor, R. W.; Boutin, S.; Lane, J. E.; McAdam, A. G.; Dantzer, B. 10.1101/594093 — evolutionary biology — Posted on 2019-03-31 53 Stability of Nitroxide Biradical TOTAPOL in Biological Samples McCoy, K. M.; Rogawski, R.; Stovicek, O.; McDermott, A. E. 10.1101/592766 — biophysics — Posted on 2019-03-31 54 STELAR: A statistically consistent coalescent-based species tree estimation method by maximizing triplet consistency Islam, M.; Sarker, K.; Das, T.; Reaz, R.; Bayzid, M. S. 10.1101/594911 — bioinformatics — Posted on 2019-03-31 55 Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis Shen, H.; Qu, Z.; Harata-Lee, Y.; Nwe Aung, T.; Cui, J.; Wang, W.; Kortschak, R. D.; Adelson, D. L. 10.1101/592964 — pharmacology and toxicology — Posted on 2019-03-31 56 The impact of sequencing depth on the inferred taxonomic composition and AMR gene content of metagenomic samples Gweon, H. S.; Shaw, L. P.; Swann, J.; De Maio, N.; AbuOun, M.; Hubbard, A. T. M.; Bowes, M. J.; Bailey, M. J.; Peto, T. E. A.; Hoosdally, S. J.; Walker, A. S.; Sebra, R. P.; Crook, D. W.; Anjum, M.; Read, D. S.; Stoesser, N.; The REHAB consortium, 10.1101/593301 — microbiology — Posted on 2019-03-31 57 A set of Arabidopsis genes involved in the accommodation of the downy mildew pathogen Hyaloperonospora arabidopsidis Ried, M. K.; Banhara, A.; Binder, A.; Hwu, F.-Y.; Gust, A. A.; Höfle, C.; Huckelhoven, R.; Nuernberger, T.; Parniske, M. 10.1101/286872 — plant biology — Posted on 2019-03-31 58 An axiomatic basis for maximal homology alignment Erives, A. J. 10.1101/593228 — genetics — Posted on 2019-03-31 59 Inhibition of the Dead Box RNA Helicase 3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation Aksenova, M.; Sybrandt, J.; Cui, B.; Sikirzhytski, V.; Ji, H.; Odhiambo, D.; Lucius, M. D.; Turner, J. R.; Broude, E.; Pena, E.; Lizzaraga, S.; Zhu, J.; Safro, I.; Wyatt, M. D.; Shtutman, M. 10.1101/591438 — neuroscience — Posted on 2019-03-31 60 An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data Stern, A. J.; Wilton, P. R.; Nielsen, R. 10.1101/592675 — genetics — Posted on 2019-03-31 61 Gene expression profiles and pathway enrichment analysis to identification of differentially expressed gene and signaling pathways in epithelial ovarian cancer based on high-throughput RNA-seq data Siavoshi, A.; Taghizadeh, M.; Dookhe, E.; Piran, M. 10.1101/566331 — genomics — Posted on 2019-03-31 62 Ribosome profiling at isoform level reveals an evolutionary conserved impact of differential splicing on the proteome Reixachs-Sole, M.; Ruiz-Orera, J.; Alba, M. M.; Eyras, E. 10.1101/582031 — genomics — Posted on 2019-03-31 63 A non-canonical role and regulations of polo-like kinase-4 in fibroblast cell-type transition Li, J.; Urabe, G.; Zhang, M.; Huang, Y.; Wang, B.; Marcho, L.; Shen, H.; Kent, K. C.; Guo, L.-W. 10.1101/570267 — cell biology — Posted on 2019-03-31 64 Translating antibiotic prescribing into antimicrobial resistance in the environment: a hazard characterisation case study Singer, A. C.; Xu, Q.; Keller, V. D. 10.1101/539536 — microbiology — Posted on 2019-03-31 65 The international sinonasal microbiome study (ISMS): a multi-centre, multi-national collaboration characterising the microbial ecology of the sinonasal cavity Paramasivan, S.; Bassiouni, A.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ramezanpour, M.; Moraitis, S.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J. 10.1101/548743 — microbiology — Posted on 2019-03-31 66 Microbiotyping the sinonasal microbiome Bassiouni, A.; Paramasivan, S.; Shiffer, A.; Dillon, M. R.; Cope, E. K.; Cooksley, C.; Ramezanpour, M.; Moraitis, S.; Ali, M. J.; Bleier, B.; Callejas, C.; Cornet, M. E.; Douglas, R. G.; Dutra, D.; Georgalas, C.; Harvey, R. J.; Hwang, P. H.; Luong, A. U.; Schlosser, R. J.; Tantilipikorn, P.; Tewfik, M. A.; Vreugde, S.; Wormald, P.-J.; Caporaso, J. G.; Psaltis, A. J. 10.1101/549311 — microbiology — Posted on 2019-03-31 67 Perceptron learning and classification in a modeled cortical pyramidal cell Moldwin, T.; Segev, I. 10.1101/464826 — neuroscience — Posted on 2019-03-31 68 The development, recognition, and learning mechanisms of an animal-like neural network Qi, F.; Wu, W. 10.1101/535724 — neuroscience — Posted on 2019-03-31 69 Genetic insights into the social organisation of the Avar period elite in the 7th century AD Carpathian Basin Csaky, V.; Gerber, D.; Koncz, I.; Csiky, G.; Mende, B. G.; Szeifert, B.; Egyed, B.; Pamjav, H.; Marcsik, A.; Molnar, E.; Palfi, G.; Gulyas, A.; Kovacsoczy, B.; Lezsak, G. M.; Lorinczy, G.; Szecsenyi-Nagy, A.; Vida, T. 10.1101/415760 — genetics — Posted on 2019-03-31 70 Repurposing the biased visibility in HiC datasets to mark dynamically regulated condensed and decondensed chromatin states genome-wide. Chandradoss, K. R.; Guthikonda, P. K.; Kethavath, S.; Dass, M.; Singh, H.; Nayak, R.; Kurukuti, S.; Sandhu, K. S. 10.1101/498006 — genomics — Posted on 2019-03-31 71 Perceptron learning and classification in a modeled cortical pyramidal cell Moldwin, T.; Segev, I. 10.1101/464826 — neuroscience — Posted on 2019-03-31 72 Patterns of fish utilisation in a tropical Indo-Pacific mangrove-coral seascape, New Caledonia Dubuc, A.; Waltham, N.; Baker, R.; Marchand, C.; Sheaves, M. 10.1101/455931 — ecology — Posted on 2019-03-31 73 Inference of tumor cell-specific transcription factor binding from cell-free DNA enables tumor subtype prediction and early detection of cancer Ulz, P.; Perakis, S.; Zhou, Q.; Moser, T.; Belic, J.; Lazzeri, I.; Wölfler, A.; Zebisch, A.; Gerger, A.; Pristauz, G.; Petru, E.; White, B.; Roberts, C. E. S.; St. John, J.; Schimek, M. G.; Geigl, J. B.; Bauernhofer, T.; Sill, H.; Bock, C.; Heitzer, E.; Speicher, M. R. 10.1101/456681 — cancer biology — Posted on 2019-03-31 74 SNPs associated with HHIP expression have differential effects on lung function in males and females Fawcett, K.; Obeidat, M.; Melbourne, C. A.; Shrine, N.; Guyatt, A. L.; John, C.; Luan, J.; Richmond, A.; Moksnes, M. R.; Granell, R.; Weiss, S.; Imboden, M.; May-Wilson, S.; Hysi, P.; Boutin, T. S.; Portas, L.; Flexeder, C.; Harris, S. E.; Wang, C. A.; Lyytikainen, L.-P.; Palviainen, T.; Foong, R. E.; Keidel, D.; Minelli, C.; Langenberg, C.; Bosse, Y.; van den Berge, M.; Sin, D. D.; Hao, K.; Campbell, A.; Porteous, D.; Padmanabhan, S.; Smith, B. H.; Evans, D.; Ring, S.; Langhammer, A.; Hveem, K.; Willer, C.; Ewert, R.; Stubbe, B.; Pirastu, N.; Klaric, L.; Joshi, P. K.; Patasova, K.; Massimo, M 10.1101/594457 — genetics — Posted on 2019-03-31 75 Rho-mediated gene transcription promotes BRAF inhibitor resistance in de-differentiated melanoma cells Misek, S. A.; Appleton, K. M.; Dexheimer, T. S.; Lisabeth, E. M.; Lo, R.; Larsen, S. D.; Gallo, K.; Neubig, R. R. 10.1101/381806 — cancer biology — Posted on 2019-03-31 76 A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease Emdin, C. A.; Haas, M.; Khera, A. V.; Aragam, K.; Chaffin, M.; Jiang, L.; Wei, W.-Q.; Feng, Q.; Karjalainen, J.; Havulinna, A.; Kiiskinen, T.; Bick, A.; Ardissino, D.; Wilson, J. G.; Schunkert, H.; McPherson, R.; Watkins, H.; Elosua, R.; Bown, M. J.; Samani, N. J.; Baber, U.; Erdmann, J.; Gupta, N.; Danesh, J.; Saleheen, D.; Daly, M.; Denny, J.; Gabriel, S.; Kathiresan, S. 10.1101/594523 — genomics — Posted on 2019-03-31 77 Opposing contributions of GABAergic and glutamatergic ventral pallidal neurons to motivational behaviours Stephenson-Jones, M.; Bravo-Rivera, C.; Ahrens, S.; Furlan, A.; Fernandes-Henriques, C.; Li, B. 10.1101/594887 — neuroscience — Posted on 2019-03-31 78 Two molecules of Has1 RNA helicase function simultaneously in the biogenesis of small and large ribosomal subunits Gnanasundram, S. V.; Kos-Braun, I. C.; Kos, M. 10.1101/594762 — molecular biology — Posted on 2019-03-31 79 Tracking microbial evolution in the human gut using Hi-C Relman, D. A.; Yaffe, E. 10.1101/594903 — microbiology — Posted on 2019-03-31 80 Dual-matrix 3D culture system as a biomimetic model of epithelial tissues Bogorodskaya, D.; McLane, J. S.; Ligon, L. A. 10.1101/594549 — cell biology — Posted on 2019-03-31 81 Exploring Structural Aspects of the Human Golgi Matrix Protein GRASP55 in Solution Reddy, S. T.; Mendes, L. F. S.; Fontana, N. A.; Costa-Filho, A. J. 10.1101/594572 — biophysics — Posted on 2019-03-31 82 Axonal transport of an insulin-like peptide mRNA promotes stress recovery in C. elegans Chandra, R.; Li, L.; Husain, Z.; Mishra, S.; Alcedo, J. 10.1101/594689 — neuroscience — Posted on 2019-03-31 83 Acute decrease in plasma membrane tension induces macropinocytosis via PLD2 activation Loh, J.; Joseph, J.; Chuang, M.-C.; Lin, S.-S.; Chang, Y.-C.; Su, Y.-A.; Liu, A. P.; Liu, Y.-W. 10.1101/594416 — cell biology — Posted on 2019-03-31 84 Septins Coordinate with Microtubules and Actin to Initiate Cell Morphogenesis Bogorodskaya, D.; Ligon, L. A. 10.1101/594515 — cell biology — Posted on 2019-03-31 85 A Ssd1 homolog impacts trehalose and chitin biosynthesis and contributes to virulence in Aspergillus fumigatus Thammahong, A.; Dhingra, S.; Bultman, K. M.; Kerkaert, J. D.; Cramer, R. A. 10.1101/594341 — microbiology — Posted on 2019-03-31 86 First-principles prediction of the information processing capacity of a simple genetic circuit Razo-Mejia, M.; Phillips, R. 10.1101/594325 — biophysics — Posted on 2019-03-31 87 A novel phyllosphere resident Protomyces species that interacts with the Arabidopsis immune system. Wang, K.; Sipilä, T.; Rajaraman, S.; Safronov, O.; Laine, P.; Auzane, A.; Mari, A.; Auvinen, P.; Paulin, L.; Kemen, E.; Salojärvi, J.; Overmyer, K. 10.1101/594028 — microbiology — Posted on 2019-03-31 88 BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila Ueberschar, M.; Wang, H.; Zhang, C.; Guo, E.; Lai, E.; Wen, J.; Dai, Q. 10.1101/593830 — developmental biology — Posted on 2019-03-31 89 Pre-Settlement Forest around Puget Sound: Eyewitness Evidence Schroeder, T. 10.1101/592733 — plant biology — Posted on 2019-03-31 90 Understanding multivariate brain activity: evaluating the effect of voxelwise noise correlations on population codes in functional magnetic resonance imaging Zhang, R.-Y.; Wei, X.-X.; Kay, K. 10.1101/592618 — neuroscience — Posted on 2019-03-31 91 Transcriptional maintenance of cortical somatostatin interneuron subtype identity during migration Munguba, H.; Nikouei, K.; Hochgerner, H.; Oberst, P.; Kouznetsova, A.; Ryge, J.; Bastista-Brito, R.; Munoz-Manchado, A. B.; Close, J.; Linnarsson, S.; Hjerling Leffler, J. 10.1101/593285 — neuroscience — Posted on 2019-03-31 92 Microsaccades and attention in a high-acuity visual alignment task. Nanjappa, R. K.; McPeek, R. M. 10.1101/592709 — neuroscience — Posted on 2019-03-31 93 Beta rhythm events predict corticospinal motor output Boenstrup, M.; Cohen, L. G.; Hussain, S. J. 10.1101/588632 — neuroscience — Posted on 2019-03-31 94 PLANT NATRIURETIC PEPTIDE A antagonizes salicylic acid-primed cell death Lee, K. P.; Liu, K.; Kim, E. Y.; Medina-Puche, L.; Duan, J.; Li, Y.; Dong, H.; Lv, R.; Li, Z.; Lozano-Duran, R.; Kim, C. 10.1101/592881 — plant biology — Posted on 2019-03-31 95 Sex Differences in Head-fixed Running Behavior Warner, E. J.; Padmanabhan, K. 10.1101/585000 — neuroscience — Posted on 2019-03-31 96 Coordinating Receptor Expression and Wiring Specificity in Olfactory Receptor Neurons Li, H.; Li, T.; Horns, F.; Li, J.; Xie, Q.; Xu, C.; Wu, B.; Kebschull, J.; Vacek, D.; Xie, A.; Luginbuhl, D.; Quake, S.; Luo, L. 10.1101/594895 — neuroscience — Posted on 2019-03-31 97 Macrophage-mediated immunoediting drives ductal carcinoma evolution: Space is the game changer Gatenbee, C.; West, J.; Baker, A. M.; Guljar, N.; Jones, L.; Graham, T. A.; Robertson-Tessi, M.; Anderson, A. R. 10.1101/594598 — cancer biology — Posted on 2019-03-31 98 The mutational landscape of a prion-like domain Bolognesi, B. M.; Faure, A. J.; Seuma, M.; Schmiedel, J. M.; Tartaglia, G.; Lehner, B. 10.1101/592121 — genetics — Posted on 2019-03-31 99 Modern clinical Mtb strains leverage the type I IFN pathway for a pro-inflammatory response in the host Shankaran, D.; Arumugam, P.; Gandotra, S.; Rao, V. K. 10.1101/594655 — immunology — Posted on 2019-03-31 100 CRISPR-Cas9 Gene Editing in Lizards Through Microinjection of Unfertilized Oocytes Rasys, A. M.; Park, S.; Ball, R. E.; Alcala, A. J.; Lauderdale, J. D.; Menke, D. B. 10.1101/591446 — genetics — Posted on 2019-03-31 101 Constitutive IRE1α signaling maintains glioblastoma cell differentiation Doultsinos, D.; McMahon, M.; Voutetakis, K.; Obacz, J.; Pineau, R.; Jouan, F.; Le Reste, P.-J.; Obiedat, A.; Samal, J.; Patterson, J. B.; Zheng, Q.; Samali, A.; Pandit, A.; Tirosh, B.; Chatziioannou, A.; Chevet, E.; Avril, T. 10.1101/594630 — cancer biology — Posted on 2019-03-31 102 Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders Byrne, E. M.; Zhu, Z.; Qi, T.; Skene, N. G.; Bryois, J.; Pardinas, A. F.; Stahl, E.; Smoller, J. W.; Rietschel, M.; Bipolar Working Group of the Psychiatric Genomics Consortium, ; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Owen, M. J.; Walters, J. T. R.; ODonovan, M. C.; McGrath, J. G.; Hjerling-Leffler, J.; Sullivan, P. F.; Goddard, M. E.; Visscher, P. M.; Yang, J.; Wray, N. R. 10.1101/592899 — genetics — Posted on 2019-03-31 103 Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates Howe, L. J.; Lawson, D. J.; Davies, N. M.; Pourcain, B. S.; Lewis, S. J.; Smith, G. D.; Hemani, G. 10.1101/418269 — genetics — Posted on 2019-03-31 104 Relative performance of Oxford Nanopore MinION vs. Pacific Biosciences Sequel third-generation sequencing platforms in identification of agricultural and forest pathogens Loit, K.; Adamson, K.; Bahram, M.; Puusepp, R.; Anslan, S.; Kiiker, R.; Drenkhan, R.; Tedersoo, L. 10.1101/592972 — microbiology — Posted on 2019-03-30 105 Characterising antibody kinetics from multiple influenza infection and vaccination events in ferrets Hay, J. A.; Laurie, K.; White, M.; Riley, S. 10.1101/411751 — immunology — Posted on 2019-03-30 106 Intergenerational effects of early adversity on survival in wild baboons Zipple, M. N.; Archie, E. A.; Tung, J.; Altmann, J.; Alberts, S. C. 10.1101/591248 — zoology — Posted on 2019-03-30 107 Genomic profiling of childhood tumor patient-derived xenograft models to enable rational clinical trial design Rokita, J. L.; Rathi, K. S.; Cardenas, M. F.; Upton, K. A.; Jayaseelan, J.; Cross, K. L.; Pfeil, J.; Ritenour, L. E.; Modi, A.; Farrel, A.; Way, G. P.; Kendsersky, N. M.; Patel, K.; Lopez, G.; Vaksman, Z.; Mayoh, C.; Nance, J.; McCoy, K.; Haber, M.; Evans, K.; McCalmont, H.; Bendak, K.; Bohm, J. W.; Marshall, G. M.; Tyrrell, V.; Kalletla, K.; Braun, F. K.; Qi, L.; Du, Y.; Zhang, H.; Lindsay, H. B.; Zhao, S.; Shu, J.; Baxter, P.; Morton, C.; Kurmashev, D.; Zheng, S.; Chen, Y.; Bowen, J.; Bryan, A. C.; Leraas, K. M.; Coppens, S. E.; Doddapaneni, H.; Momin, Z.; Zhang, W.; Sacks, G. I.; Hart, L. S 10.1101/566455 — genomics — Posted on 2019-03-30 108 Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota Blow, F.; Gioti, A.; Goodhead, I. B.; Kalyva, M.; Kampouraki, A.; Vontas, J.; Darby, A. C. 10.1101/590489 — evolutionary biology — Posted on 2019-03-30 109 Differential Expression of N- and O-glycans on HeLa Cells -Revealed by Direct Fluorescent Glycan Labeling with Recombinant Sialyltransferases Wu, Z.; Person, A. D.; Burton, A. J.; Singh, R.; Burroughs, B.; Fryxell, D.; Tatge, T. J.; Manning, T.; Wu, G.; Swift, K.; Kalabokis, V. 10.1101/580571 — cell biology — Posted on 2019-03-30 110 Reducing variability in along-tract analysis with diffusion profile realignment St-Jean, S.; Chamberland, M.; Viergever, M. A.; Leemans, A. 10.1101/541920 — neuroscience — Posted on 2019-03-30 111 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy Seaborne, R. A.; Hughes, D. C.; Turner, D. C.; Owens, D. J.; Baehr, L. M.; Gorski, P.; Semenova, E. A.; Borisov, O. V.; Larin, A. K.; Popov, D. V.; Generozov, E. V.; Sutherland, H.; Ahmetov, I. I.; Jarvis, J. C.; Bodine, S. C.; Sharples, A. P. 10.1101/592980 — physiology — Posted on 2019-03-30 112 Parsimonious scenario for the emergence of viroid-like replicons de novo Catalan, P.; Elena, S. F.; Cuesta, J. A.; Manrubia, S. 10.1101/593640 — evolutionary biology — Posted on 2019-03-30 113 Differences in player position running velocity at lactate thresholds among male professional German soccer players Schwesig, R.; Schulze, S.; Reinhardt, L.; Delank, K.-S.; Laudner, K. G.; Hermassi, S. 10.1101/592188 — physiology — Posted on 2019-03-30 114 Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and - independent phagosomal signals that contribute to phagocytosis and inflammation Benjamin, S. J.; Hawley, K. L.; Vera-Licona, M. P.; LaVake, C. J.; Cervantes, J. L.; Burns, R.; Luo, O.; Ruan, Y.; Caimano, M.; Radolf, J. D.; Salazar, J. C. 10.1101/593566 — immunology — Posted on 2019-03-30 115 A Comparative Assessment of Visceral Leishmaniasis Burden in Two Eco-epidemiologically Different Countries, India and Sudan Mubayi, A.; Barley, K.; Safan, M.; Castillo-Chavez, C. 10.1101/592220 — epidemiology — Posted on 2019-03-30 116 Environmental light is required for maintenance of long-term memory in Drosophila Inami, S.; Sato, S.; Kondo, S.; Tanimoto, H.; Kitamoto, T.; Sakai, T. 10.1101/592667 — neuroscience — Posted on 2019-03-30 117 Flat Electrode Contacts for Peripheral Nerve Stimulation Bucksot, J.; Wells, A. J.; Rahebi, K. C.; Sivaji, V.; Romero-Ortega, M.; Kilgard, M. P.; Rennaker, R. L.; Hays, S. A. 10.1101/593467 — bioengineering — Posted on 2019-03-30 118 Epithelial micro-invasion by Streptococcus pneumoniae induces epithelial-derived innate immunity during colonisation at the human mucosal surface Weight, C. M.; Venturini, C.; Pojar, S.; Jochems, S.; Reine, J.; Nikolaou, E.; Solorzano, C.; Noursadeghi, M.; Brown, J. S.; Ferreira, D. M.; Heyderman, R. S. 10.1101/281576 — immunology — Posted on 2019-03-30 119 Euplotid: A quantized geometric model of the eukaryotic cell Borges-Rivera, D. 10.1101/170159 — biophysics — Posted on 2019-03-30 120 State-dependent geometry of population activity in rat auditory cortex Kobak, D.; Pardo-Vazquez, J. L.; Valente, M.; Machens, C.; Renart, A. 10.1101/501338 — neuroscience — Posted on 2019-03-30 121 TDP-43 proteinopathy impairs neuronal mRNP granule mediated postsynaptic local translation and mRNA metabolism Wong, C.-E.; Tsai, K.-J. 10.1101/589416 — neuroscience — Posted on 2019-03-30 122 Increased molecular plasticity along the septotemporal axis of the hippocampus is associated with network functioning. Sotiriou, E.; Angelatou, F.; Papatheodoropoulos, C. 10.1101/593095 — neuroscience — Posted on 2019-03-30 123 Synaptotagmin 1 oligomers clamp and regulate different modes of neurotransmitter release Tagliatti, E.; Bello, O. D.; Mendonca, P. R. F.; Kotzadimitriou, D.; Nicholson, E.; Coleman, J.; Timofeeva, Y.; Rothman, J.; Krishnakumar, S.; Volynski, K. 10.1101/594051 — neuroscience — Posted on 2019-03-30 124 Patterns and potential drivers of intraspecific variability in the body elemental composition of a terrestrial consumer, the snowshoe hare (Lepus americanus) Rizzuto, M.; Leroux, S. J.; Vander Wal, E.; Wiersma, Y. F.; Heckford, T. R.; Balluffi-Fry, J. 10.1101/594101 — ecology — Posted on 2019-03-30 125 High-Speed Automatic Characterization of Rare Events in Flow Cytometric Data Qi, Y.; Fang, Y.; Sinclair, D. R.; Guo, S.; Alberich-Jorda, M.; Lu, J.; Tenen, D. G.; Kharas, M. G.; Pyne, S. 10.1101/591644 — bioinformatics — Posted on 2019-03-30 126 Immortalization of different breast epithelial cell types results in distinct mitochondrial mutagenesis Kwon, S.; Kim, S.; Nebeck, H.; Ahn, E. H. 10.1101/592832 — genomics — Posted on 2019-03-30 127 Estimating the sensitivity of associations between risk factors and outcomes to shared genetic effects Pingault, J.-B.; Rijsdijk, F.; Schoeler, T.; Choi, S. W.; Selzam, S.; Krapohl, E.; O'Reilly, P. F.; Dudbridge, F. 10.1101/592352 — genetics — Posted on 2019-03-30 128 Transposable temperate phages promote the evolution of divergent social strategies in Pseudomonas aeruginosa populations O'Brien, S.; Kummerli, R.; Paterson, S.; Winstanley, C.; Brockhurst, M. A. 10.1101/593798 — evolutionary biology — Posted on 2019-03-30 129 Spatiotemporal Dynamics of Stream Fish Assemblages Over Four Decades Zbinden, Z. D. 10.1101/592469 — ecology — Posted on 2019-03-30 130 Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation Cerqueira Campos, F.; Alegot, H.; Dennis, C.; Fritsch, C.; Isabella, A.; Pouchin, P.; Bardot, O.; Horne-Badovinac, S.; Mirouse, V. 10.1101/591628 — developmental biology — Posted on 2019-03-30 131 Convergent genes shape budding yeast pericentromeres Paldi, F.; Alver, B.; Robertson, D.; Schalbetter, S. A.; Kerr, A.; Kelly, D. A.; Neale, M. J.; Baxter, J.; Marston, A. 10.1101/592782 — cell biology — Posted on 2019-03-30 132 FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy Diaz Osterman, C. J.; Ozmadenci, D.; Kleinschmidt, E. G.; Taylor, K. N.; Barrie, A. M.; Jiang, S.; Bean, L. M.; Sulzmaier, F. J.; Jean, C.; Tancioni, I.; Anderson, K.; Uryu, S.; Cordasco, E. A.; Li, J.; Chen, X. L.; Fu, G.; Ojalill, M.; Rappu, P.; Heino, J.; Mark, A. M.; Xu, G.; Fisch, K. M.; Kolev, V. N.; Weaver, D. T.; Pachter, J. A.; Gyorffy, B.; McHale, M. T.; Connolly, D. C.; Molinolo, A.; Stupack, D. G.; Schlaepfer, D. D. 10.1101/594184 — cancer biology — Posted on 2019-03-30 133 DeepSSV: detecting somatic small variants in paired tumor and normal sequencing data with convolutional neural network Meng, J.; Victor, B.; He, Z.; Salim, A. 10.1101/555680 — bioinformatics — Posted on 2019-03-30 134 Ultrasound- and microbubble-mediated targeted delivery of therapeutic microRNA-loaded nanocarriers to deep liver and kidney tissues in pigs di Ianni, T.; Bose, R. J. C.; Sukumar, U. K.; Bachawal, S.; Wang, H.; Telichko, A.; Herickhoff, C. D.; Robinson, E.; Baker, S.; Vilches-Moure, J. G.; Felt, S. A.; Gambhir, S. S.; Paulmurugan, R.; Dahl, J. D. 10.1101/592931 — bioengineering — Posted on 2019-03-30 135 Initiation of chromosome replication controls both division and replication cycles in E. coli through a double-adder mechanism Witz, G.; van Nimwegen, E. J.; Julou, T. 10.1101/593590 — systems biology — Posted on 2019-03-30 136 Deep learning-based imaging classification identified cingulate island sign in dementia with Lewy bodies Iizuka, T.; Fukasawa, M.; Kameyama, M. 10.1101/592865 — neuroscience — Posted on 2019-03-30 137 Differences in sodium channel densities in the apical dendrites of pyramidal cells of the electrosensory lateral line lobe. Motipally, S. I.; Allen, K. M.; Williamson, D. K.; Marsat, G. 10.1101/592758 — neuroscience — Posted on 2019-03-30 138 Feature overlap modulates rapid semantic but not lexical integration of novel associations by means of fast mapping Zaiser, A.-K.; Meyer, P.; Bader, R. 10.1101/594218 — neuroscience — Posted on 2019-03-30 139 Chronic corticosterone administration induces negative valence and impairs positive valence behaviors in mice Dieterich, A.; Srivastava, P.; Sharif, A.; Stech, K.; Samuels, B. A. 10.1101/593632 — neuroscience — Posted on 2019-03-30 140 Co-occurrence of multiple CRISPRs and cas clusters suggests epistatic interactions Bernheim, A.; Bikard, D.; Touchon, m.; Rocha, E. 10.1101/592600 — genomics — Posted on 2019-03-30 141 Multi-Trait Improvement by Predicting Genetic Correlations in Breeding Crosses Neyhart, J.; Lorenz, A. J.; Smith, K. P. 10.1101/593210 — genetics — Posted on 2019-03-30 142 Whole genome duplication potentiates inter-specific hybridisation and niche shifts in Australian burrowing frogs Neobatrachus Novikova, P. Y.; Brennan, I. G.; Booker, W.; Mahony, M.; Doughty, P.; Lemmon, A. R.; Lemmon, E. M.; Yant, L.; Van de Peer, Y.; Keogh, J. S.; Donnellan, S. C. 10.1101/593699 — evolutionary biology — Posted on 2019-03-30 143 Population fragmentation leads to morpho-functional variation in British red squirrels (Sciurus vulgaris) Cox, P. G.; Morris, P. J.; Kitchener, A. C. 10.1101/593319 — evolutionary biology — Posted on 2019-03-30 144 Pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers Boyle, C. J.; Higgins, C. A.; Masen, M. A.; Masouros, S. D. 10.1101/592477 — bioengineering — Posted on 2019-03-30 145 Ligands, receptors and transcription factors that mediate inter-cellular and intra-cellular communication during ovarian follicle development Penalver Bernabe, B.; Woodruff, T.; Broadbelt, L.; Shea, L. 10.1101/594234 — systems biology — Posted on 2019-03-30 146 A toolset of constitutive promoters for metabolic engineering of Rhodosporidium toruloides Nora, L. C.; Wehrs, M.; Kim, J.; Cheng, J.-F.; Tarver, A.; Simmons, B. A.; Magnuson, J.; Harmon-Smith, M.; Silva-Rocha, R.; Gladden, J. M.; Mukhopadhyay, A.; Skerker, J. M.; Kirby, J. 10.1101/592774 — synthetic biology — Posted on 2019-03-30 147 MARGO (Massively Automated Real-time GUI for Object-tracking), a platform for high-throughput ethology Werkhoven, Z.; Rohrsen, C.; Qin, C.; Brembs, B.; de Bivort, B. L. 10.1101/593046 — neuroscience — Posted on 2019-03-30 148 ezTrack: An open-source video analysis pipeline for the investigation of animal behavior Pennington, Z. T.; Dong, Z.; Bowler, R.; Feng, Y.; Vetere, L. M.; Shuman, T.; Cai, D. J. 10.1101/592592 — neuroscience — Posted on 2019-03-30 149 Analysis of miniaturization effects and channel selection strategies for EEG sensor networks with application to auditory attention detection Mundanad Narayanan, A.; Bertrand, A. 10.1101/593194 — neuroscience — Posted on 2019-03-30 150 Opposing chromatin remodelers control transcription initiation frequency and start site selection Kubik, S.; Challal, D.; Bruzzone, M. J.; Dreos, R.; Mattarocci, S.; Bucher, P.; Libri, D.; Shore, D. 10.1101/592816 — molecular biology — Posted on 2019-03-30 151 Prokaryotic SPHINX sequences are conserved in mammalian brain and participate in neurodegeneration Manuelidis, L.; Szigeti-Buck, K. 10.1101/593954 — evolutionary biology — Posted on 2019-03-30 152 Drivers of amphibian population dynamics and asynchrony at local and continental scales Cayuela, H.; Griffiths, R. A.; Zakaria, N.; Arntzen, J. W.; Priol, P.; Lena, J.-P.; Besnard, A.; Joly, P. 10.1101/592683 — ecology — Posted on 2019-03-30 153 Severely stressful natal environment does not impact lifetime reproductive success of adult boobies Ortega, S.; Rodriguez, C.; Drummond, H. 10.1101/594226 — ecology — Posted on 2019-03-30 154 A Bile Duct-on-a-Chip with Organ-Level Functions Du, Y.; Khandekar, G.; Llewellyn, J.; Polacheck, W.; Chen, C. S.; Wells, R. G. 10.1101/594291 — bioengineering — Posted on 2019-03-30 155 Crosstalk and Ultrasensitivity in Protein Degradation Pathways Mallela, A.; Nariya, M. K.; Deeds, E. J. 10.1101/594085 — systems biology — Posted on 2019-03-30 156 Differential impacts of the head on Platynereis dumerilii peripheral circadian rhythms Arboleda, E.; Zurl, M.; Tessmar-Raible, K. 10.1101/593772 — physiology — Posted on 2019-03-30 157 A new strategy for identifying mechanisms of drug-drug interaction using transcriptome analysis: Compound Kushen injection as a proof of principle Shen, H. Y.; Qu, Z.; Harata-Lee, Y.; Cui, J.; Nwe Aung, T.; Wang, W.; Kortschak, R. D.; Adelson, D. L. 10.1101/592956 — pharmacology and toxicology — Posted on 2019-03-30 158 PhenoMS-ML: Phenotypic Screening by Mass Spectrometry and Machine Learning van Oosten, L. N.; Klein, C. D. 10.1101/593244 — pharmacology and toxicology — Posted on 2019-03-30 159 Mitochondrial dynamics and mitophagy are necessary for proper invasive growth in Rice Blast Kou, Y.; He, Y.; Qiu, J.; Shu, Y.; Yang, F.; Deng, Y.; Naqvi, N. I. 10.1101/592915 — pathology — Posted on 2019-03-30 160 Cell-type and region-specific nucleus accumbens AMPAR plasticity associated with morphine reward, reinstatement, and spontaneous withdrawal Madayag, A.; Gomez, D.; Anderson, E.; Ingebretson, A.; Thomas, M.; Hearing, M. 10.1101/592519 — neuroscience — Posted on 2019-03-30 161 Relationship between faecal microbiota and plasma metabolome in rats fed NK603 and MON810 GM maize from the GMO90+ study Mesnage, R.; Le Roy, C.; Biserni, M.; Salles, B.; Antoniou, M. N. 10.1101/593343 — molecular biology — Posted on 2019-03-30 162 Cutibacterium acnes antibiotic production shapes niche competition in the human skin microbiome Claesen, J.; Spagnolo, J. B.; Flores Ramos, S.; Kurita, K. L.; Byrd, A. L.; Aksenov, A. A.; Melnik, A. V.; Wong, W. R.; Wang, S.; Hernandez, R. D.; Donia, M. S.; Dorrestein, P. C.; Kong, H. H.; Segre, J. A.; Linington, R. G.; Fischbach, M. A.; Lemon, K. P. 10.1101/594010 — microbiology — Posted on 2019-03-30 163 Controlling Heterogeneity and Increasing Titer from Riboswitch-Regulated Bacillus subtilis Spores for Time-Delayed Protein Expression Applications Tamiev, D.; Lantz, A.; Vezeau, G.; Salis, H.; Reuel, N. 10.1101/592659 — microbiology — Posted on 2019-03-30 164 Common DNA sequence variation influences 3-dimensional conformation of the human genome Gorkin, D.; Qiu, Y.; Hu, M.; Fletez-Brant, K.; Liu, T.; Schmitt, A.; Noor, A.; Chiou, J.; Gaulton, K.; Sebat, J.; Li, Y.; Hansen, K.; Ren, B. 10.1101/592741 — genomics — Posted on 2019-03-30 165 Antagonistic coevolution between hosts and sexually transmitted infections Ashby, B. 10.1101/590232 — evolutionary biology — Posted on 2019-03-30 166 Single Nucleotide Mapping of the Locally Accessible Trait Space in Yeast Reveals Pareto Fronts that Constrain Initial Adaptation Li, Y.; Petrov, D.; Sherlock, G. 10.1101/593947 — evolutionary biology — Posted on 2019-03-30 167 FIND: Identifying Functionally and Structurally Important Features in Protein Sequences with Deep Neural Networks Murali, R.; Hemp, J.; Orphan, V.; Bisk, Y. 10.1101/592808 — bioinformatics — Posted on 2019-03-30 168 RNase H1 and H2 are differentially regulated to eliminate RNA-DNA hybrids Lockhart, A.; Pires, V.; Bento, F.; Kellner, V.; Luke-Glaser, S.; Luke, B. 10.1101/593152 — molecular biology — Posted on 2019-03-30 169 An essential RNA-binding lysine residue in the Nab3 RRM domain undergoes mono and tri-methylation Lee, K. Y.; Chopra, A.; Biggar, K. K.; Meneghini, M. 10.1101/592923 — molecular biology — Posted on 2019-03-30 170 Detection of Spacer Precursors Formed In Vivo During Primed CRISPR Adaptation Shiriaeva, A. A.; Savitskaya, E.; Datsenko, K. A.; Vvedenskaya, I. O.; Fedorova, I.; Morozova, N.; Metlitskaya, A.; Sabantsev, A.; Nickels, B. E.; Severinov, K.; Semenova, E. 10.1101/594259 — microbiology — Posted on 2019-03-30 171 CGGBP1 regulates chromatin barrier activity and CTCF occupancy at repeats Patel, D. K.; Patel, M.; Singh, U. 10.1101/593137 — genomics — Posted on 2019-03-30 172 Single- nuclei RNA sequencing from human brain to study for Mendelian and sporadic AD Del-Aguila, J. L.; Li, Z.; Dube, U.; Mihindukulasuriya, K. A.; Budde, J. P.; Fernandez, M. V.; Ibanez, L.; Bradley, J.; Wang, F.; Bergmann, K.; Davenport, R.; Morris, J. C.; Holtzman, D. M.; Perrin, R. J.; Benitez, B. A.; Dougherty, J.; Cruchaga, C.; Harari, O. 10.1101/593756 — genomics — Posted on 2019-03-30 173 An axiomatic basis for maximal homology alignment Erives, A. J. 10.1101/593228 — genetics — Posted on 2019-03-30 174 Cohesin disrupts polycomb-dependent chromosome interactions Rhodes, J.; Feldmann, A.; Hernandez-Rodriguez, B.; Diaz, N.; Brown, J.; Fursova, N.; Blackledge, N.; Prathapan, P.; Dobrinic, P.; Huseyin, M.; Szczurek, A.; Kruse, K.; Nasmyth, K.; Buckle, V.; Vaquerizas, J. M.; Klose, R. 10.1101/593970 — genetics — Posted on 2019-03-30 175 Urban ecology of arboviral mosquito vectors along the Kenyan coast Karisa, J. K.; Muriu, S.; Omuoyo, D.; Karia, B.; Nyamwaya, D.; Rono, M.; Warimwe, G.; Mwangangi, J.; Mbogo, C. 10.1101/593350 — ecology — Posted on 2019-03-30 176 Just how big is intraspecific trait variation in fungal fruit bodies? Dawson, S. K.; Jonsson, M. 10.1101/593517 — ecology — Posted on 2019-03-30 177 High-throughput quantitative detection of basal autophagy and autophagic flux using image cytometry Senthilkumar, G.; Skiba, J. H.; Kimple, R. 10.1101/590513 — cell biology — Posted on 2019-03-30 178 Connectivity Measures for Signaling Pathway Topologies Franzese, N.; Groce, A.; Murali, T. M.; Ritz, A. 10.1101/593913 — bioinformatics — Posted on 2019-03-30 179 Augmented Interval List: a novel data structure for efficient genomic interval search Feng, J.; Ratan, A.; Sheffield, N. 10.1101/593657 — bioinformatics — Posted on 2019-03-30 180 SCOPE: a normalization and copy number estimation method for single-cell DNA sequencing Wang, R.; Lin, D.-Y.; Jiang, Y. 10.1101/594267 — bioinformatics — Posted on 2019-03-30 181 Patient-specific haemodynamic simulations of complex aortic dissections informed by commonly available clinical datasets Bonfanti, M.; Franzetti, G.; Maritati, G.; Homer-Vanniasinkam, S.; Balabani, S.; Diaz-Zuccarini, V. 10.1101/593780 — bioengineering — Posted on 2019-03-30 182 Pat1 activates late steps in mRNA decay by multiple mechanisms Lobel, J. H.; Tibble, R. W.; Gross, J. D. 10.1101/594168 — biochemistry — Posted on 2019-03-30 183 Two gut microbes are necessary and sufficient for normal cognition in Drosophila melanogaster DeNieu, M.; Mounts, K.; Manier, M. 10.1101/593723 — animal behavior and cognition — Posted on 2019-03-30 184 A library of cell-surface and secreted proteins from Schistosoma mansoni identifies early serological markers of infection Crosnier, C.; Protasio, A. V.; Rinaldi, G.; Wilson, S.; Berriman, M.; Wright, G. J. 10.1101/593616 — immunology — Posted on 2019-03-30 185 Conditional GWAS analysis identifies putative disorder-specific SNPs for psychiatric disorders Byrne, E.; Zhu, Z.; Qi, T.; Skene, N.; Bryois, J.; Pardinas, A.; Stahl, E.; Smoller, J.; Rietschel, M.; Bipolar Working Group of the Psychiatric Genomics, ; Major Depressive Disorder Working Group of the Psy, ; Owen, M.; Walters, J.; O'Donovan, M.; McGrath, J.; Hjerling-Leffler, J.; Sullivan, P.; Goddard, M.; Visscher, P. M.; Yang, J.; Wray, N. R. 10.1101/592899 — genetics — Posted on 2019-03-30 186 Meta-MultiSKAT: Multiple phenotype meta-analysis for region-based association test Dutta, D.; Gagliano Taliun, S. A.; Weinstock, J. S.; Zawistowski, M.; Sidore, C.; Fritsche, L. G.; Cucca, F.; Schlessinger, D.; Abecasis, G. R.; Brummett, C. M.; Lee, S. 10.1101/593814 — genetics — Posted on 2019-03-30 187 Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers Schuhmacher, L.-N.; Callejo, G.; Srivats, S.; Smith, E. S. J. 10.1101/166272 — neuroscience — Posted on 2019-03-30 188 Multidimensional estimation of cardiac arrhythmia potential across space and time Sahli Costabal, F.; Seo, K.; Ashley, E.; Kuhl, E. 10.1101/545863 — biophysics — Posted on 2019-03-29 189 Functional relevance of dual olfactory bulb in olfactory coding Kuruppath, P.; Belluscio, L. 10.1101/588996 — neuroscience — Posted on 2019-03-29 190 Development of senescence biomarkers in the common woodlouse Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Bech, S. 10.1101/583914 — evolutionary biology — Posted on 2019-03-29 191 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy Seaborne, R. A.; Hughes, D. C.; Turner, D. C.; Owens, D. J.; Baehr, L. M.; Gorski, P.; Semenova, E. A.; Borisov, O. V.; Larin, A. K.; Popov, D. V.; Generozov, E. V.; Sutherland, H.; Ahmetov, I. I.; Jarvis, J. C.; Bodine, S. C.; Sharples, A. P. 10.1101/592980 — physiology — Posted on 2019-03-29 192 Yellow Fever Vaccine Protects Resistant and Susceptible Mice Against Zika Virus Infection Vicente Santos, A. C.; Guedes-da-Silva, F. H.; Dumard, C. H.; Ferreira, V. N. S.; da Costa, I. P. S.; Machado, R. A.; Barros-Aragao, F. G. Q.; Neris, R. L. S.; Dos-Santos, J. S.; Assuncao-Miranda, I.; Figueiredo, C. P.; Dias, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.; Oliveira, A. C.; Silva, J. L. 10.1101/587444 — immunology — Posted on 2019-03-29 193 Proteins encoded by Novel ORFs have increased disorder but can be biochemically regulated and harbour pathogenic mutations Jagannathan, N. S.; Meena, N.; Bhayankaram, K. P.; Prabakaran, S. 10.1101/562835 — genetics — Posted on 2019-03-29 194 Machine learning applied to predicting microorganism growth temperatures and enzyme catalytic optima Li, G.; Rabe, K. S.; Nielsen, J.; Engqvist, M. K. 10.1101/522342 — bioinformatics — Posted on 2019-03-29 195 Genome-scale model of Rhodotorula toruloides metabolism Tiukova, I. A.; Prigent, S.; Sandgren, M.; Nielsen, J.; Kerkhoven, E. J. 10.1101/528489 — systems biology — Posted on 2019-03-29 196 PRISMOID: a comprehensive 3D structure database for post-translational modifications and mutations with functional impact Li, F.; Fan, C.; Marquez-Lago, T. T.; Leier, A.; Revote, J.; Jia, C.; Zhu, Y.; Smith, A. I.; Webb, G. I.; Liu, Q.; Wei, L.; Li, J.; Song, J. 10.1101/523308 — bioinformatics — Posted on 2019-03-29 197 Impact of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S. 10.1101/433011 — evolutionary biology — Posted on 2019-03-29 198 A simple genetic architecture and low constraint allows rapid floral evolution in a diverse and recently radiating plant genus Kostyun, J. L.; Gibson, M. J. S.; King, C. M.; Moyle, L. C. 10.1101/516377 — evolutionary biology — Posted on 2019-03-29 199 A keeper of many crypts: the parasitoid Euderus set manipulates the behavior of a taxonomically diverse array of oak gall wasp species Ward, A. K. G.; Khodor, O. S.; Egan, S. P.; Weinersmith, K. L.; Forbes, A. A. 10.1101/516104 — ecology — Posted on 2019-03-29 200 Alcohol consumption and mate choice in UK Biobank: comparing observational and Mendelian randomization estimates Howe, L. J.; Lawson, D. J.; Davies, N. M.; St. Pourcain, B.; Lewis, S. J.; Davey Smith, G.; Hemani, G. 10.1101/418269 — genetics — Posted on 2019-03-29 201 Molecular evolution across developmental time reveals rapid divergence in early embryogenesis Cutter, A. D.; Garrett, R. H.; Mark, S.; Wang, W.; Sun, L. 10.1101/518621 — evolutionary biology — Posted on 2019-03-29 202 An agent-based framework for improving wildlife disease surveillance: A case study of chronic wasting disease in Missouri white-tailed deer. Belsare, A.; Gompper, M. E.; Keller, B.; Sumners, J.; Hansen, L.; Millspaugh, J. 10.1101/478610 — ecology — Posted on 2019-03-29 203 The heparin-binding proteome in normal pancreas and murine experimental acute pancreatitis Nunes, Q. M.; Su, D.; Brownridge, P. J.; Simpson, D. M.; Sun, C.; li, y.; Bui, P. T. P.; Zhang, X.; Huang, W.; Rigden, D. J.; Beynon, R. J.; Sutton, R.; Fernig, D. G. 10.1101/497271 — biochemistry — Posted on 2019-03-29 204 Proof of concept continuous event logging in living cells Shur, A.; Murray, R. M. 10.1101/225151 — synthetic biology — Posted on 2019-03-29 205 Electrophysiological correlates of hyperoxia during resting-state EEG in awake human subjects Vuong, W.; Kizuk, S. A. D.; MacLean, J.; Dickson, C. T.; Mathewson, K. 10.1101/355941 — neuroscience — Posted on 2019-03-29 206 Cardiac afferent activity modulates early neural signature of error detection during skilled performance Bury, G.; Garcia Huescar, M.; Bhattacharya, J.; Herrojo Ruiz, M. 10.1101/484584 — neuroscience — Posted on 2019-03-29 207 Estimating DNA-DNA interaction frequency from Hi-C data at restriction-fragment resolution Cameron, C. J.; Dostie, J.; Blanchette, M. 10.1101/377523 — bioinformatics — Posted on 2019-03-29 208 Genome sequence of the euryhaline Javafish medaka, Oryzias javanicus: a small aquarium fish model for studies on adaptation to salinity. Takehana, Y.; Zahm, M.; Cabau, C.; Klopp, C.; Roques, C.; Bouchez, O.; Donnadieu, C.; Barrachina, C.; Journot, L.; Kawaguchi, M.; Yasumasu, S.; Ansai, S.; Naruse, K.; Inoue, K.; Shinzato, C.; Schartl, M.; Guiguen, Y.; Herpin, A. 10.1101/593673 — genomics — Posted on 2019-03-29 209 Single cell transcriptomics identifies master regulators of dysfunctional pathways in SOD1 ALS motor neurons Namboori, S. C.; Thomas, P.; Ames, R.; Garrett, L. O.; Willis, C. R. G.; Stanton, L. W.; Bhinge, A. 10.1101/593129 — genomics — Posted on 2019-03-29 210 Degenerate time-dependent network dynamics anticipate seizures in human epileptic brain Tauste Campo, A.; Principe, A.; Ley, M.; Rocamora, R.; Deco, G. 10.1101/080739 — neuroscience — Posted on 2019-03-29 211 The representational space of observed actions Tucciarelli, R.; Wurm, M.; Baccolo, E.; Lingnau, A. 10.1101/592071 — neuroscience — Posted on 2019-03-29 212 Driving the scalability of DNA-based information storage systems Tomek, K. J.; Volkel, K.; Simpson, A.; Hass, A. G.; Indermaur, E. W.; Tuck, J.; Keung, A. J. 10.1101/591594 — bioengineering — Posted on 2019-03-29 213 Seasonal stability and dynamics of DNA methylation in plants in a natural environment Ito, T.; Nishio, H.; Tarutani, Y.; Emura, N.; Honjo, M. N.; Toyoda, A.; Fujiyama, A.; Kakutani, T.; Kudoh, H. 10.1101/589465 — plant biology — Posted on 2019-03-29 214 Versatile proteome labelling in fruit flies with SILAF Schober, F. A.; Atanassov, I.; Moore, D.; Wedell, A.; Freyer, C.; Wredenberg, A. 10.1101/590315 — molecular biology — Posted on 2019-03-29 215 CD2 expression acts as a quantitative checkpoint for immunological synapse structure and T-cell activation. Demetriou, P.; Abu-Shah, E.; McCuaig, S.; Mayya, V.; Valvo, S.; Korobchevskaya, K.; Friedrich, M.; Mann, E.; Lee, L. Y.; Starkey, T.; Kutuzov, M. A.; Afrose, J.; Siokis, A.; Oxford IBD Cohort Investigators, ; Meyer-Hermann, M.; Depoil, D.; Dustin, M. L. 10.1101/589440 — immunology — Posted on 2019-03-29 216 Compounding the disturbance: Family forest owner reactions to invasive forest insects Markowski-Lindsay, M.; Borsuk, M. E.; Butler, B. J.; Duveneck, M. J.; Holt, J.; Kittredge, D. B.; Laflower, D.; MacLean, M. G.; Orwig, D.; Thompson, J. R. 10.1101/590331 — ecology — Posted on 2019-03-29 217 Microglia actively remodels adult hippocampal neurogenesis through the phagocytosis secretome Diaz-Aparicio, I.; Paris, I.; Sierra-Torre, V.; Plaza-Zabala, A.; Rodriguez-Iglesias, N.; Marquez-Ropero, M.; Beccari, S.; Abiega, O.; Alberdi, E.; Matute, C.; Bernales, I.; Schulz, A.; Otrokocsi, L.; Sperlagh, B.; Happonen, K. E.; Lemke, G.; Maletic-Savatic, M.; Valero, J.; Sierra, A. 10.1101/583849 — cell biology — Posted on 2019-03-29 218 Valid and powerful statistical test for decoding accuracy-proposal of Permutation-based Information Prevalence Inference using the i-th order statistic Hirose, S. 10.1101/578930 — neuroscience — Posted on 2019-03-29 219 Variational Treatment of Trial-by-Trial Drift-Diffusion Models of Behaviour Vincent, M.; Alexandre, Z. 10.1101/220517 — neuroscience — Posted on 2019-03-29 220 UBR5 is a Novel E3 Ubiquitin Ligase involved in Skeletal Muscle Hypertrophy and Recovery from Atrophy Seaborne, R. A.; Hughes, D. C.; Turner, D. C.; Owens, D. J.; Baehr, L. M.; Gorski, P.; Semenova, E. A.; Borisov, O. V.; Larin, A. K.; Popov, D. V.; Generozov, E. V.; Sutherland, H.; Ahmetov, I. I.; Jarvis, J. C.; Sue, B. C.; Sharples, A. P. 10.1101/592980 — physiology — Posted on 2019-03-29 221 Induction of p73, Δ133p53, Δ160p53, pAKT leads to neuroprotection via DNA repair by 5-LOX inhibition Shekhar, S.; Dey, S. 10.1101/593202 — neuroscience — Posted on 2019-03-29 222 C. elegans discriminate colors without eyes or opsins Ghosh, D. D.; Jin, X.; Nitabach, M. 10.1101/092072 — neuroscience — Posted on 2019-03-29 223 Altered hypothalamic microstructure in human obesity Thomas, K.; Beyer, F.; Lewe, G.; Zhang, R.; Schindler, S.; Schoenknecht, P.; Stumvoll, M.; Villringer, A.; Witte, A. V. 10.1101/593004 — neuroscience — Posted on 2019-03-29 224 Inhibition of the DDX3 prevents HIV-1 Tat and cocaine-induced neurotoxicity by targeting microglia activation Aksenova, M.; Sybrand, J.; Cui, B.; Sikirzhytski, V.; Ji, H.; Odhiambo, D.; Lucius, M.; Turner, J. R.; Broude, E.; Pena, E.; Lizzaraga, S.; Zhu, J.; Safro, I.; Wyatt, M. D.; Shtutman, M. 10.1101/591438 — neuroscience — Posted on 2019-03-29 225 A ‘proton ratchet’ for coupling the membrane potential to protein transport Allen, W. J.; Corey, R. A.; Watkins, D. W.; Pereira, G. C.; Oliveira, A. S. F.; Collinson, I. 10.1101/592543 — biochemistry — Posted on 2019-03-29 226 A sensitive period in the neural phenotype of language in blind individuals Pant, R.; Kanjlia, S.; Bedny, M. 10.1101/592345 — neuroscience — Posted on 2019-03-29 227 Class I and II aminoacyl-tRNA synthetase tRNA groove discrimination created the first synthetase·tRNA cognate pairs and was therefore essential to the origin of genetic coding Carter, C. W.; Wills, P. R. 10.1101/593269 — genetics — Posted on 2019-03-29 228 How often do Protein Genes Navigate Valleys of Low Fitness? Nelson, E. D.; Grishin, N. V. 10.1101/592444 — genetics — Posted on 2019-03-29 229 Structure-function analysis of ZAR1 immune receptor reveals key molecular interactions for activity Baudin, M.; Schreiber, K. J.; Martin, E. C.; Petrescu, A. J.; Lewis, J. 10.1101/592824 — plant biology — Posted on 2019-03-29 230 Precuneus stimulation alters the neural dynamics of autobiographical memory retrieval Hebscher, M.; Ibrahim, C.; Gilboa, A. 10.1101/592436 — neuroscience — Posted on 2019-03-29 231 MicroRNA levels in bone and blood change during bisphosphonate and teriparatide therapy in an animal model of postmenopausal osteoporosis Kocijan, R.; Weigl, M.; Skalicky, S.; Geiger, E.; Ferguson, J.; Leinfellner, G.; Heimel, P.; Pietschmann, P.; Grillari, J.; Redl, H.; Hackl, M. 10.1101/591990 — molecular biology — Posted on 2019-03-29 232 Extended insight into the preponderance of LRRs - a docking & simulation study with members of the TLR1 subfamily Dey, D.; Dhar, D.; Das, S.; Maulik, A.; Basu, S. 10.1101/592626 — bioinformatics — Posted on 2019-03-29 233 Genomics In The Jungle: Using Portable Sequencing As A Teaching Tool In Field Courses Watsa, M.; Erkenswick, G. A.; Pomerantz, A.; Prost, S. 10.1101/581728 — scientific communication and education — Posted on 2019-03-29 234 Is there more room to improve? The lifespan trajectory of procedural learning and its relationship to the between- and within-group differences in average response times Juhasz, D.; Nemeth, D.; Janacsek, K. 10.1101/593582 — neuroscience — Posted on 2019-03-29 235 Multi-omics co-localization with genome-wide association studies reveals context-specific mechanisms of asthma risk variants Soliai, M.; Kato, A.; Stanhope, C. T.; Norton, J. E.; Naughton, K. A.; Klinger, A. I.; Kern, R. C.; Tan, B. K.; Schleimer, R. P.; Nicolae, D. L.; Pinto, J. M.; Ober, C. 10.1101/593558 — genetics — Posted on 2019-03-29 236 Divergent mitochondrial and nuclear OXPHOS genes are candidates for genetic incompatibilities in Ficedula Flycatchers van der Heijden, E.; McFarlane, E.; van der Valk, T.; Qvarnstrom, A. 10.1101/588756 — evolutionary biology — Posted on 2019-03-29 237 Patterning of the vertebrate head in time and space by BMP signalling Zhu, K.; Spaink, H. P.; Durston, A. 10.1101/592451 — developmental biology — Posted on 2019-03-29 238 Characterisation of Staphylococcus aureus lipids by nanoelectrospray ionisation tandem mass spectrometry (nESI-MS/MS) Young, S. A.; Desbois, A. P.; Coote, P. J.; Smith, T. K. 10.1101/593483 — microbiology — Posted on 2019-03-29 239 Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosis Kupz, A.; Pai, S.; Giacomin, P. R.; Whan, J. A.; Walker, R.; Hammoudi, P.-M.; Smith, N.; Miller, C. M. 10.1101/593574 — microbiology — Posted on 2019-03-29 240 Health service utilisation lags behind maternal diseases or illnesses during pregnancy in rural south Ethiopia: A prospective cohort study Borde, M. T.; Loha, E.; Johansson, K. A.; Lindtjorn, B. 10.1101/593525 — epidemiology — Posted on 2019-03-29 241 Dynamics of soil nematode communities revealed significant variation in greenhouse with different continuous cropping years Tian, X.; Zhao, X.; Mao, Z.; Xie, B. 10.1101/593541 — ecology — Posted on 2019-03-29 242 Vibrational behavior of psyllids (Hemiptera: Psylloidea): functional morphology and mechanisms Liao, Y.-C.; Wu, Z.-Z.; Yang, M.-M. 10.1101/593533 — animal behavior and cognition — Posted on 2019-03-29 243 Highly reproducible murine model of oral Salmonella infection via inoculated food Nilsson, O. R.; Kari, L.; Steele-Mortimer, O. 10.1101/593442 — microbiology — Posted on 2019-03-29 244 Circulating Th17.1 cells as candidate for prediction of therapeutic response to abatacept in patients with rheumatoid arthritis: exploratory research Maeda, S.; Osaga, S.; Maeda, T.; Takeda, N.; Tamechika, S.-y.; Naniwa, T.; Niimi, A. 10.1101/593475 — immunology — Posted on 2019-03-29 245 Feeding behavior of Aedes (Aedimorphus) vexans arabiensis, a Rift valley fever virus vector in the Ferlo pastoral ecosystem of Senegal. BITEYE, B.; Fall, A. G.; Seck, M. T.; Ciss, M.; Diop, M.; Gimonneau, G. 10.1101/593491 — epidemiology — Posted on 2019-03-29 246 Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic β-cells Pratt, E. P. S.; Harvey, K. E.; Salyer, A. E.; Tang, s.; Hockerman, G. 10.1101/593418 — pharmacology and toxicology — Posted on 2019-03-29 247 Gene Cascade Finder: A tool for identification of gene cascades and its application in Caenorhabditis elegans Ito, M.; Nomoto, Y.; Kubota, Y.; Kasahara, K.; Tomita, A.; Oshime, T.; Yamashita, H.; Fahmi, M. 10.1101/593400 — genomics — Posted on 2019-03-29 248 Multivariate Genome-wide Association Analyses Reveal the Genetic Basis of Seed Fatty Acid Composition in Oat (Avena sativa L.) Carlson, M. O.; Montilla-Bascon, G.; Hoekenga, O. A.; Tinker, N. A.; Poland, J.; Baseggio, M.; Sorrells, M.; Jannink, J.-L.; Gore, M. A.; Yeats, T. H. 10.1101/589952 — genetics — Posted on 2019-03-29 249 Assessing the multiple dimensions of poverty. Data mining approaches to the 2004-14 Health and Demographic Surveillance System in Cuatro Santos, Nicaragua Kallestal, C.; Zelaya Blandon, E.; Pena, R.; Perez, W.; Contreras, M.; Persson, L.-A.; Sysoev, O.; Ekholm Selling, K. 10.1101/593426 — epidemiology — Posted on 2019-03-29 250 Lipidome profiles of postnatal day 2 vaginal swabs reflect fat composition of gilts postnatal diet Harlow, K.; Ferreira, C. R.; Sobreira, T. J. P.; Casey, T. M.; Stewart, K. 10.1101/593392 — developmental biology — Posted on 2019-03-29 251 A combined strategy of neuropeptide predictions and tandem mass spectrometry identifies evolutionarily conserved ancient neuropeptides in the sea anemone Nematostella vectensis Hayakawa, E.; Watanabe, H.; Menschaert, G.; Holstein, T.; Baggerman, G.; Schoofs, L. 10.1101/593384 — biochemistry — Posted on 2019-03-29 252 Quantitative Colour Pattern Analysis (QCPA): A Comprehensive Framework for the Analysis of Colour Patterns in Nature van den Berg, C. P.; Troscianko, J.; Endler, J. A.; Marshall, N. J.; Cheney, K. L. 10.1101/592261 — animal behavior and cognition — Posted on 2019-03-29 253 Effects of single cage housing in the rat and mouse pilocarpine models of epilepsy Manouze, H.; Ghestem, A.; Poillerat, V.; Bennis, M.; Ba-M'hamed, S.; Benoliel, J.-J.; Becker, C.; Bernard, C. 10.1101/214528 — neuroscience — Posted on 2019-03-29 254 Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell Lymphocyte Attenuator Bitra, A.; Nemcovicova, I.; Picarda, G.; Doukov, T.; Wang, J.; Benedict, C. A.; Zajonc, D. M. 10.1101/591883 — immunology — Posted on 2019-03-29 255 Control of human testis-specific gene expression Brown, J. 10.1101/593376 — developmental biology — Posted on 2019-03-29 256 Polygenic architecture of human neuroanatomical diversity Biton, A.; Traut, N.; Poline, J.-B.; Aribisala, B. S.; Bastin, M. E.; Bülow, R.; Cox, S. R.; Deary, I. J.; Grabe, H. J.; Hagenaars, S.; Hashimoto, R.; Munoz Maniega, S.; Nauck, M.; Royle, N. A.; Teumer, A.; Valdes Hernandez, M.; Völker, U.; Wardlaw, J. M.; Wittfeld, K.; Alzheimer's Disease Neuroimaging Initiative, ; Bourgeron, T.; Toro, R. 10.1101/592337 — neuroscience — Posted on 2019-03-29 257 IκBζ is constitutively expressed in human and murine airway epithelium Sundaram, K.; Mitra, S.; Jaynes, F.; Lorscheid, S.; Steiner, H.; Flechtner, A.; Sarkar, A.; Shilo, K.; Boyaka, P. N.; Schulze-Osthoff, K.; Wewers, M. D. 10.1101/255331 — immunology — Posted on 2019-03-29 258 Noisy Perturbation Models Distinguish Network Specific from Embedding Variability Piehler, A. 10.1101/550467 — systems biology — Posted on 2019-03-29 259 A simplified analytical model of sound propagationin the human ear Gambin, W. L. 10.1101/571034 — bioengineering — Posted on 2019-03-29 260 Investigating the longitudinal consistency and genetic architecture of non-cognitive skills, and their relation to educational attainment Morris, T. T.; Davey Smith, G.; Van den Berg, G.; Davies, N. M. 10.1101/470682 — genetics — Posted on 2019-03-29 261 Non-catalytic binding sites induce weaker long-range evolutionary rate gradients than catalytic sites in enzymes Sharir-Ivry, A.; Xia, Y. 10.1101/554436 — evolutionary biology — Posted on 2019-03-29 262 Block HSIC Lasso: model-free biomarker detection for ultra-high dimensional data Climente-Gonzalez, H.; Azencott, C.-A.; Kaski, S.; Yamada, M. 10.1101/532192 — bioinformatics — Posted on 2019-03-29 263 diffcyt: Differential discovery in high-dimensional cytometry via high-resolution clustering Weber, L. M.; Nowicka, M.; Soneson, C.; Robinson, M. D. 10.1101/349738 — bioinformatics — Posted on 2019-03-29 264 Axonal tree morphology and signal propagation dynamics improve interneuron classification Ofer, N.; Shefi, O.; Yaari, G. 10.1101/414615 — neuroscience — Posted on 2019-03-29 265 The effect of stimulus choice on an EEG-based objective measure of speech intelligibility Verschueren, E.; Vanthornhout, J.; Francart, T. 10.1101/421727 — neuroscience — Posted on 2019-03-29 266 EFFECT OF PARENTAL CARE ON REPRODUCTIVE SUCCESS IN WOOD STORKS (MYCTERIA AMERICANA) Bruant, A.; Picardi, S.; Frederick, P.; Basille, M. 10.1101/592840 — zoology — Posted on 2019-03-28 267 Hierarchy of connectivity-function relationship of the human cortex revealed through predicting activity across functional domains Wu, D.; Fan, L.; Song, M.; Wang, H.; Chu, C.; Yu, S.; Jiang, T. 10.1101/591776 — neuroscience — Posted on 2019-03-28 268 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C. 10.1101/589366 — bioinformatics — Posted on 2019-03-28 269 A stochastic spatial model for heterogeneity in cancergrowth Queiroga, A. S.; de Morais, M. C. C.; Tortelli, T. C.; Chammas, R.; Ramos, A. F. 10.1101/584573 — systems biology — Posted on 2019-03-28 270 Revealing virulence potential of clinical and environmental Aspergillus fumigatus isolates using Whole-genome sequencing Puertolas-Balint, F.; Rossen, J. W.; Oliveira dos Santos, C.; Chlebowicz, M. A.; Raangs, E.; van Putten, M. L.; Sola-Campoy, P. J.; Han, L.; Schmidt, M.; Garcia-Cobos, S. 10.1101/587402 — microbiology — Posted on 2019-03-28 271 Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility Ku, A. A.; Kongara, S.; Hu, H.-M.; Zhao, X.; Wu, D.; McCormick, F.; Balmain, A.; Bandyopadhyay, S. 10.1101/591677 — cancer biology — Posted on 2019-03-28 272 A triple-hybrid cross reveals a new hybrid incompatibility locus between D. melanogaster and D. sechellia Cooper, J. C.; Guo, P.; Bladen, J.; Phadnis, N. 10.1101/590588 — evolutionary biology — Posted on 2019-03-28 273 Resilience Analysis for Competing Populations Cesar Fassoni, A.; de Carvalho Braga, D. 10.1101/578609 — ecology — Posted on 2019-03-28 274 Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum Gueho, A.; Bosmani, C.; Soldati, T. 10.1101/592717 — systems biology — Posted on 2019-03-28 275 Aligning Needs: Integrating Citizen Science Efforts into Schools Through Service Requirements. Tsueng, G.; Kumar, A.; Nanis, M.; Su, A. I. 10.1101/304766 — scientific communication and education — Posted on 2019-03-28 276 First evidence that intrinsic fetal heart rate variability exists and is affected by hypoxic pregnancy Frasch, M. G.; Herry, C.; Niu, Y.; Giussani, D. A. 10.1101/242107 — physiology — Posted on 2019-03-28 277 A gene based approach to test genetic association based on an Optimally Weighted Combination of Multiple Traits Zhang, J.; Qiuying, S.; Guanfu, L.; Wang, X. 10.1101/592568 — genetics — Posted on 2019-03-28 278 Single-molecule visualization of the effects of ionic strength and crowding on structure-mediated interactions in supercoiled DNA molecules Scott, S.; Shaheen, C.; McGuinness, B.; Metera, K.; Kouzine, F.; Levens, D.; Benham, C. J.; Leslie, S. 10.1101/591008 — biophysics — Posted on 2019-03-28 279 TET2 regulates the neuroinflammatory response in microglia Carrillo-Jimenez, A.; Deniz, O.; Niklison-Chirou, M.; Ruiz-Laza, R.; Salomao, K.; Stratoulias, V.; Amoroux, R.; Yip, P.; Vilalta, A.; Cheray, M.; Scott-Egerton, A. M.; Rivas, E.; Tayara, K.; Garcia-Dominguez, I.; Garcia-Revilla, J.; Fernandez-Martin, J. C.; Espinosa-Oliva, A. M.; Shen, X.; StGeorge-Hyslop, P.; Brown, G.; Hajkova, P.; Joseph, B.; Venero, J. L.; Branco, M. R.; Burguillos, M. A. 10.1101/592055 — neuroscience — Posted on 2019-03-28 280 A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits Foley, C. N.; Staley, J. R.; Breen, P. G.; Sun, B. B.; Kirk, P. D.; Burgess, S.; Howson, J. M. 10.1101/592238 — genetics — Posted on 2019-03-28 281 Intergenerational effects of early adversity on survival in wild baboons Zipple, M. N.; Archie, E. A.; Tung, J.; Altmann, J.; Alberts, S. C. 10.1101/591248 — zoology — Posted on 2019-03-28 282 A segregating human allele of SPO11 modeled in mice disrupts timing and amounts of meiotic recombination, causing oligospermia and a decreased ovarian reserve. Tran, T. N.; Schimenti, J. C. 10.1101/592576 — genetics — Posted on 2019-03-28 283 Genetic Testing Preferences and Intentions in U.S. Patients with Clinically Diagnosed Familial Hypercholesterolemia Wand, H.; Sturm, A. C.; Erby, L.; Kindt, I.; Klein, W. M. P. 10.1101/587923 — genetics — Posted on 2019-03-28 284 Research grade marijuana supplied by the National Institute on Drug Abuse is genetically divergent from commercially available Cannabis Schwabe, A. L.; Hansen, C. J.; Hyslop, R. M.; McGlaughlin, M. E. 10.1101/592725 — genetics — Posted on 2019-03-28 285 A Mechanism for Epithelial-Mesenchymal Heterogeneity in a Population of Cancer Cells Tripathi, S.; Levine, H.; Jolly, M. K. 10.1101/592691 — cancer biology — Posted on 2019-03-28 286 Bocaparvovirus, Erythroparvovirus and Tetraparvovirus in New World Monkeys from Central America Chaves, A.; Ibarra-Cerdena, C. N.; Lopez-Perez, A. M.; Monge, O.; Avendano, R.; Urena-Saborio, H.; Chavarria, M.; Zaldana, K.; Sanchez, L.; Ortiz-Malavassi, E.; Suzan, G.; Foley, J.; Gutierrez-Espeleta, G. A. 10.1101/588079 — epidemiology — Posted on 2019-03-28 287 Validation and characterization of a DNA methylation alcohol biomarker across the life course Yousefi, P. D.; Richmond, R.; Langdon, R.; Ness, A. R.; Liu, C.; Levy, D.; Relton, C.; Suderman, M.; Zuccolo, L. 10.1101/591404 — epidemiology — Posted on 2019-03-28 288 An approximate full-likelihood method for inferring selection and allele frequency trajectories from DNA sequence data Stern, A. J.; Wilton, P. R.; Nielsen, R. 10.1101/592675 — genetics — Posted on 2019-03-28 289 Factors underpinning discrepant findings from reviews on the same topic: A systematic analysis of Cochrane and non-Cochrane reviews Nunan, D.; Hacke, C. 10.1101/574046 — epidemiology — Posted on 2019-03-28 290 Prediction of rapid kidney function decline using machine learning combining blood biomarkers and electronic health record data Nadkarni, G. N.; Fleming, F.; McCullough, J. R.; Chauhan, K.; Verghese, D. A.; He, J. C.; Quackenbush, J.; Bonventre, J. V.; Murphy, B.; Parikh, C. R.; Donovan, M.; Coca, S. G. 10.1101/587774 — epidemiology — Posted on 2019-03-28 291 Polygenic risk score for Alzheimer’s disease and trajectories of cardiometabolic risk factors in children Korologou-Linden, R.; O'Keeffe, L.; Howe, L.; Davey Smith, G.; Jones, H.; Anderson, E. L.; Stergiakouli, E. 10.1101/580548 — epidemiology — Posted on 2019-03-28 292 Accurate forecasts of the effectiveness of interventions against Ebola may require models that account for variations in symptoms during infection Hart, W.; Hochfilzer, L.; Cunniffe, N.; Lee, H.; Nishiura, H.; Thompson, R. N. 10.1101/592030 — epidemiology — Posted on 2019-03-28 293 Global phylogeographical patterns in the spread of foot-and-mouth disease virus Jara, M.; Frias-De-Diego, A.; Dellicour, S.; Baele, G.; Machado, G. 10.1101/590612 — epidemiology — Posted on 2019-03-28 294 Phenotyping women based on dietary macronutrients, physical activity and body weight using machine-learning tools Ramyaa, R.; Hosseini, O.; Krishnan, G. P.; Krishnan, S. 10.1101/587220 — epidemiology — Posted on 2019-03-28 295 Increasing global heterogeneity in the life expectancy of older populations Liou, L.; Subramanian, S.; Joe, W. 10.1101/589630 — epidemiology — Posted on 2019-03-28 296 High burden and seasonal variation of paediatric scabies and pyoderma prevalence in The Gambia: a cross-sectional study Armitage, E. P.; Senghore, E.; Darboe, S.; Barry, M.; Camara, J.; Bah, S.; Marks, M.; Cerami, C.; Roca, A.; Antonio, M.; Turner, C.; de Silva, T. 10.1101/591537 — epidemiology — Posted on 2019-03-28 297 The effect of combined patching and citalopram on visual acuity in adults with amblyopia: a randomized, crossover, placebo-controlled trial Lagas, A. K.; Black, J. M.; Russell, B. R.; Kydd, R. R.; Thompson, B. 10.1101/587980 — clinical trials — Posted on 2019-03-28 298 ‘Early Rectangularization’ of under-5 mortality in sub-Saharan Africa: compression, convergence, inequality Mejia-Guevara, I.; Tuljapurkar, S. 10.1101/591925 — epidemiology — Posted on 2019-03-28 299 The causal effect of adiposity on hospital costs: Mendelian Randomization analysis of over 300,000 individuals from the UK Biobank Dixon, P.; Hollingworth, W.; Harrison, S.; Davies, N.; Davey Smith, G. 10.1101/589820 — epidemiology — Posted on 2019-03-28 300 Global state of deworming coverage and inequity in low-income and middle-income countries: a spatiotemporal study of household health surveys Lo, N. C.; Heft-Neal, S.; Coulibaly, J. T.; Leonard, L.; Bendavid, E.; Addiss, D. G. 10.1101/589127 — epidemiology — Posted on 2019-03-28 301 Impact of a caries preventive intervention in remote Indigenous Australian children Lalloo, R.; SANTOSH KUMAR, T.; Kroon, J.; Jamieson, L. M.; Johnson, N. 10.1101/585935 — epidemiology — Posted on 2019-03-28 302 Phylodynamic and Evolutionary analysis of Rotavirus G12 in Africa Motayo, B. O.; Oluwasemowo, O. O.; Olusola, B. A.; Opayele, A.; Faneye, A. O. 10.1101/591297 — epidemiology — Posted on 2019-03-28 303 Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD). Cole, E. J.; Stimpson, K. H.; Gulser, M.; Cherian, K.; Tischler, C.; Nejad, R.; Bentzley, B. S.; Pankow, H.; Choi, E.; Aaron, H.; Espil, F. M.; Pannu, J.; Xiao, X.; Duvio, D.; Solvason, H. B.; Hawkins, J.; Keller, J.; Schatzberg, A. F.; Sudheimer, K. D.; Williams, N. R. 10.1101/581280 — clinical trials — Posted on 2019-03-28 304 State-dependent geometry of population activity in rat auditory cortex Kobak, D.; Pardo-Vazquez, J. L.; Valente, M.; Machens, C.; Renart, A. 10.1101/501338 — neuroscience — Posted on 2019-03-28 305 Voice patterns in schizophrenia: A systematic review and Bayesian meta-analysis Parola, A.; Simonsen, A.; Bliksted, V.; Fusaroli, R. 10.1101/583815 — bioinformatics — Posted on 2019-03-28 306 Ecological causes of uneven diversification and richness in the mammal tree of life Upham, N. S.; Esselstyn, J. A.; Jetz, W. 10.1101/504803 — evolutionary biology — Posted on 2019-03-28 307 μSleep: A Spontaneous C. elegans Sleep State Regulated by Satiety, Thermosensation and Mechanosensation Gonzales, D. L.; Zhou, J.; Robinson, J. T. 10.1101/547075 — neuroscience — Posted on 2019-03-28 308 Loss of cytoplasmic incompatibility and minimal fecundity effects explain relatively low Wolbachia frequencies in Drosophila mauritiana Meany, M. K.; Conner, W. R.; Richter, S. V.; Bailey, J. A.; Turelli, M.; Cooper, B. S. 10.1101/461574 — evolutionary biology — Posted on 2019-03-28 309 Designing Minimal Genomes Using Whole-Cell Models Rees, J.; Chalkley, O.; Landon, S.; Purcell, O.; Marucci, L.; Grierson, C. 10.1101/344564 — synthetic biology — Posted on 2019-03-28 310 Bidirectional Long-Term Synaptic Zinc Plasticity at Mouse Glutamatergic Synapses Vogler, N. W.; Tzounopoulos, T. 10.1101/320671 — neuroscience — Posted on 2019-03-28 311 Real-time projections of epidemic transmission and estimation of vaccination impact during an Ebola virus disease outbreak in Northeastern Democratic Republic of Congo Worden, L.; Wannier, R.; Hoff, N. A.; Musene, K.; Selo, B.; Mossoko, M.; Okitolonda-Wemakoy, E.; Muyembe-Tamfum, J. J.; Rutherford, G. W.; Lietman, T. M.; Rimoin, A. W.; Porco, T. C.; Kelly, J. D. 10.1101/461285 — epidemiology — Posted on 2019-03-28 312 Polygenic architecture of human neuroanatomical diversity Biton, A.; Traut, N.; Poline, J.-B.; Aribisala, B. S.; Bastin, M. E.; Bülow, R.; Cox, S. R.; Deary, I. J.; Grabe, H. J.; Hagenaars, S.; Hashimoto, R.; Munoz Maniega, S.; Nauck, M.; Royle, N. A.; Teumer, A.; Valdes Hernandez, M.; Völker, U.; Wardlaw, J. M.; Wittfeld, K.; Alzheimer's Disease Neuroimaging Initiative, ; Bourgeron, T.; Toro, R. 10.1101/592337 — neuroscience — Posted on 2019-03-28 313 Improving spatial normalization of brain diffusion MRI to measure longitudinal changes of tissue microstructure in human cortex and white matter. Jacobacci, F.; Jovicich, J.; Lerner, G.; Amaro, E.; Armony, J.; Doyon, J.; Della-Maggiore, V. 10.1101/590521 — neuroscience — Posted on 2019-03-28 314 The mRNA-bound proteome of Leishmania mexicana: novel genetic insight into an ancient parasite de Pablos, L. M.; Ferreira, T. R.; Dowle, A. A.; Forrester, S.; Parry, E.; Newling, K.; Walrad, P. B. 10.1101/592402 — molecular biology — Posted on 2019-03-28 315 Extensive epitranscriptomic methylation of A and C residues on murine leukemia virus transcripts enhances viral gene expression Courtney, D.; Chalem, A.; Bogerd, H. P.; Law, B. A.; Kennedy, E. M.; Holley, C. L.; Cullen, B. R. 10.1101/591545 — microbiology — Posted on 2019-03-28 316 EPS8 facilitates uncoating of influenza A virus Larson, G. P.; Tran, V.; Yu, S.; Cai, Y.; Higgins, C. A.; Smith, D. M.; Baker, S. F.; Radoshitzky, S. R.; Kuhn, J. H.; Mehle, A. 10.1101/592485 — microbiology — Posted on 2019-03-28 317 Construction and analysis of an interologous protein-protein interaction network of Camellia sinensisleaf (TeaLIPIN) from RNA-Seq datasets Singh, G.; Singh, V.; Singh, V. 10.1101/592394 — systems biology — Posted on 2019-03-28 318 Spatiotemporal dynamics of synthetic microbial consortia in microfluidic devices Alnahhas, R.; Winkle, J. J.; Hirning, A. J.; Karamched, B.; Ott, W.; Josic, K.; Bennett, M. R. 10.1101/590505 — synthetic biology — Posted on 2019-03-28 319 Ubiquitin receptors are required for substrate-mediated activation of the proteasome’s unfolding ability Cundiff, M. D.; Hurley, C. M.; Wong, J. D.; Bashyal, A.; Rosenberg, J.; Reichard, E. L.; Nassif, N. D.; Brodbelt, J.; Kraut, D. 10.1101/592378 — biochemistry — Posted on 2019-03-28 320 On a Robust, Sensitive Cell-Free Method for Pseudomonas Sensing and Quantification Seto, J.; Buske, P.; Laurie, M. 10.1101/256438 — synthetic biology — Posted on 2019-03-28 321 WACS: Improving Peak Calling by Optimally Weighting Controls Awdeh, A.; Turcotte, M.; Perkins, T. J. 10.1101/582650 — bioinformatics — Posted on 2019-03-28 322 Short term memory properties of sensory neural architectures Dubreuil, A. M. 10.1101/590851 — neuroscience — Posted on 2019-03-28 323 Childhood socio-economic disadvantage predicts reduced myelin growth across adolescence and young adulthood Ziegler, G.; Moutoussis, M.; Hauser, T. U.; Fearon, P.; Bullmore, E. T.; Goodyer, I. M.; Fonagy, P.; Jones, P. B.; NeuroScience in Psychiatry Network consortium, ; Lindenberger, U.; Dolan, R. J. 10.1101/589713 — neuroscience — Posted on 2019-03-28 324 A sound-sensitive source of alpha oscillations in human non-primary auditory cortex Billig, A. J.; Herrmann, B.; Rhone, A. E.; Gander, P. E.; Nourski, K. V.; Snoad, B. F.; Kovach, C. K.; Kawasaki, H.; Howard, M. A.; Johnsrude, I. S. 10.1101/590323 — neuroscience — Posted on 2019-03-28 325 The Complete Chloroplast Genome of Tetraselmis desikacharyi (Chlorodendrophyceae) and Phylogenetic Analysis Li, L.; Li, H.; Sahu, S. K.; Xu, Y.; Wang, H.; Liang, H.; Wang, S. 10.1101/591727 — genomics — Posted on 2019-03-28 326 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J. 10.1101/524702 — molecular biology — Posted on 2019-03-28 327 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G.; Hong, Y. 10.1101/588624 — cell biology — Posted on 2019-03-28 328 Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids Smits, L. M.; Magni, S.; Grzyb, K.; Antony, P. M.; Krueger, R.; Skupin, A.; Bolognin, S.; Schwamborn, J. 10.1101/589598 — neuroscience — Posted on 2019-03-28 329 Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits Gleason, K. J.; Yang, F.; Pierce, B.; He, X.; Chen, L. S. 10.1101/579581 — genomics — Posted on 2019-03-28 330 WACS: Improving Peak Calling by Optimally Weighting Controls Awdeh, A.; Turcotte, M.; Perkins, T. J. 10.1101/582650 — bioinformatics — Posted on 2019-03-28 331 Quantitative Colour Pattern Analysis (QCPA): A Comprehensive Framework for the Analysis of Colour Patterns in Nature van den Berg, C. P.; Troscianko, J.; Endler, J. A.; Marshall, N. J.; Cheney, K. L. 10.1101/592261 — animal behavior and cognition — Posted on 2019-03-28 332 Rule-governed Dynamic Stochastic Equilibration of Multicellular Motion In Vivo During Olfactory Neurogenesis Warrier, V.; Cluzeau, C.; Chen, B.-C.; Green-Saxena, A.; Bergey, D. E.; Betzig, E.; Saxena, A. 10.1101/591479 — systems biology — Posted on 2019-03-28 333 Space-independent community and hub structure of functional brain networks Zamani Esfahlani, F.; Bertolero, M.; Bassett, D.; Betzel, R. 10.1101/590935 — neuroscience — Posted on 2019-03-28 334 Within-subject consistency of paired associative stimulation as assessed by linear mixed models. Ottenhoff, M. J.; Fani, L.; Erler, N. S.; Castricum, J.; Obdam, I. F.; van der Vaart, T.; Kushner, S. A.; de Wit, M.-C. Y.; Elgersma, Y.; Tulen, J. 10.1101/434431 — neuroscience — Posted on 2019-03-28 335 During hippocampal inactivation, grid cells maintain their synchrony, even when the grid pattern is lost Almog, N.; Tocker, G.; Bonnevie, T.; Moser, M.-B.; Moser, E. I.; Derdikman, D. 10.1101/592006 — neuroscience — Posted on 2019-03-28 336 Surveillance-embedded genomic outbreak resolution of methicillin-susceptible Staphylococcus aureus in a neonatal intensive care unit Cremers, A. J. H.; Coolen, J.; Bleeker-Rovers, C.; van der Geest-Blankert, N.; Haverkate, D.; Hendriks, H.; Henriet, S.; Huynen, M.; Kolwijck, E.; Liem, D.; Melchers, W.; Rossen, J.; Zoll, J.; van Heijst, A.; Hopman, J.; Wertheim, H. 10.1101/584359 — microbiology — Posted on 2019-03-28 337 Integrating detection of copy neutral chromosomal losses in a clinical setting in leukemia and lymphoma by means of allelic imbalance and read depth ratio comparison Hansen, M. C.; Cedile, O.; Ludvigsen, M.; Kjeldsen, E.; Moeller, P. L.; Abildgaard, N.; Hokland, P.; Nyvold, C. G. 10.1101/590752 — bioinformatics — Posted on 2019-03-28 338 High-throughput Phenotyping with Temporal Sequences Estiri, H.; McCoy, T. H.; Wagholikar, K. B.; Goodson, A. P.; Murphy, K.; Murphy, S. N. 10.1101/590307 — bioinformatics — Posted on 2019-03-28 339 Area-specific mapping of binocular disparity across mouse visual cortex La Chioma, A.; Bonhoeffer, T.; Hübener, M. 10.1101/591412 — neuroscience — Posted on 2019-03-28 340 A Robust Model for Circadian Redox Oscillations del Olmo, M.; Kramer, A.; Herzel, H. 10.1101/590570 — molecular biology — Posted on 2019-03-28 341 Feedback loops in the Plk4-STIL-HsSAS6 network coordinate site selection for procentriole formation Takao, D.; Watanabe, K.; Kuroki, K.; Kitagawa, D. 10.1101/591834 — cell biology — Posted on 2019-03-28 342 Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect Johnson, K. E.; Howard, G.; Mo, W.; Strasser, M. K.; Lima, E. A. B. F.; Huang, S.; Brock, A. 10.1101/585216 — cancer biology — Posted on 2019-03-28 343 Multiomics data analysis using tensor decomposition based unsupervised feature extraction --Comparison with DIABLO-- Taguchi, Y.-h. 10.1101/591867 — bioinformatics — Posted on 2019-03-28 344 A topological data analysis based classification method for multiple measurement Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R. 10.1101/569210 — bioinformatics — Posted on 2019-03-28 345 Regulatory sites for known and novel splicing in human basal ganglia are enriched for disease-relevant information Guelfi, S.; D'Sa, K.; Botia, J. A.; Vandrovcova, J.; Reynolds, R. H.; Zhang, D.; Trabzuni, D.; Collado-Torres, L.; Thomason, A.; Quijada Leyton, P.; Gagliano, S. A.; Nalls, M. A.; UK Brain Expression Consortium, ; Small, K. S.; Smith, C.; Ramasamy, A.; Hardy, J. A.; Weale, M. E.; Ryten, M. 10.1101/591156 — bioinformatics — Posted on 2019-03-28 346 Contribution of self- and other-regarding motives to (dis)honesty Shuster, A.; Levy, D. J. 10.1101/590208 — neuroscience — Posted on 2019-03-28 347 Chitosan films for microfluidic studies of single bacteria and perspectives for antibiotics susceptibility testing Mignot, T.; Treguier, J.; Bugnicourt, L.; Gay, G.; Diallo, M.; Islam, S. T.; Toro, A.; Theodoly, O.; David, L.; SUDRE, G. 10.1101/591602 — microbiology — Posted on 2019-03-28 348 Bacteriophage adherence to mucus mediates preventive protection against pathogenic bacteria Almeida, G. M.; Laanto, E.; Ashrafi, R.; Sundberg, L.-R. 10.1101/592097 — microbiology — Posted on 2019-03-28 349 Identification of novel neuroprotective loci modulating ischemic stroke volume in a cross between wild-derived inbred mouse strains Lee, H. K.; Widmayer, S. J.; Aylor, D. L.; Marchuk, D. 10.1101/591669 — genetics — Posted on 2019-03-28 350 Contingent Convergence: The ability to detect convergent genomic evolution is dependent on demographic similarity Whiting, J. R.; Fraser, B. A. 10.1101/592105 — evolutionary biology — Posted on 2019-03-28 351 Identifying Lipid Membrane Packing Defects in 3-Dimension: When Depth Does Matter Tripathy, M.; Srivastava, A. 10.1101/591784 — biophysics — Posted on 2019-03-28 352 Distance Measures for Tumor Evolutionary Trees DiNardo, Z.; Tomlinson, K.; Ritz, A.; Oesper, L. 10.1101/591107 — bioinformatics — Posted on 2019-03-28 353 Fingerprinting CANDO: Increased Accuracy with Structure and Ligand Based Shotgun Drug Repurposing Schuler, J.; Samudrala, R. 10.1101/591123 — bioinformatics — Posted on 2019-03-28 354 Human influences on antipredator behaviour in Darwin’s finches Gotanda, K. M. 10.1101/591651 — animal behavior and cognition — Posted on 2019-03-28 355 Changepoint detection versus reinforcement learning: Separable neural substrates approximate different forms of Bayesian inference Pauli, W. M.; Jones, M. 10.1101/591818 — neuroscience — Posted on 2019-03-28 356 Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation KEELE, G. R.; Quach, B. C.; Israel, J. W.; Zhou, Y.; Chappell, G. A.; Lewis, L.; Safi, A.; Simon, J. M.; Cotney, P.; Crawford, G. E.; Wright, F. A.; Valdar, W.; Rusyn, I.; Furey, T. S. 10.1101/588723 — genomics — Posted on 2019-03-28 357 Transgenerational plasticity of inducible defenses: combined effects of grand-parental, parental and current environments Tariel, J.; Plénet, S.; Luquet, E. 10.1101/589945 — evolutionary biology — Posted on 2019-03-28 358 Statistical Analysis of Variability in TnSeq Data Across Conditions Using Zero-Inflated Negative Binomial Regression Subramaniyam, S.; DeJesus, M. A.; Saveri, A.; Smith, C. M.; Baker, R. E.; Ehrt, S.; Schnappinger, D.; Sassetti, C. M.; Ioerger, T. R. 10.1101/590281 — bioinformatics — Posted on 2019-03-28 359 Anopheles bionomics, insecticide resistance mechanisms and malaria transmission in the Korhogo area, northern Cote d Ivoire: a pre-intervention study Zogo, B.; Soma, D. D.; Tchiekoi, B. N. C.; Some, A.; Ahoua Alou, L. P.; Koffi, A. A.; Fournet, F.; Dahounto, A.; Coulibaly, B.; Kande, S.; Dabire, R. K.; Baba-Moussa, L.; Moiroux, N.; Pennetier, C. 10.1101/589556 — zoology — Posted on 2019-03-28 360 Optimizing root measurements in rhizotrons Ytting, N. K.; kirkegaard, j.; Thorup-Kristensen, K. 10.1101/587329 — plant biology — Posted on 2019-03-28 361 Information Integration and Collective Motility in Phototactic Cyanobacteria Menon, S. N.; Varuni, P.; Menon, G. I. 10.1101/590778 — microbiology — Posted on 2019-03-28 362 Distinct biogeographic origins of androgenetic Corbicula lineages followed by genetic captures Etoundi, E.; Marescaux, J.; Vastrade, M.; Debortoli, N.; Hedtke, S. M.; Pigneur, L.-M.; Virgo, J.; Flot, J.-F.; Van Doninck, K. 10.1101/590836 — evolutionary biology — Posted on 2019-03-28 363 Animal evolution coincides with a novel degree of freedom in exocytic transport processes Kollmar, M.; Welz, T.; Straub, F.; Alzahofi, N.; Hatje, K.; Briggs, D. A.; Samol-Wolf, A.; Burkhardt, P.; Hume, A.; Kerkhoff, E. 10.1101/591974 — cell biology — Posted on 2019-03-28 364 Modeling latent flows on single-cell data using the Hodge decomposition Maehara, K.; Ohkawa, Y. 10.1101/592089 — bioinformatics — Posted on 2019-03-28 365 Substrate structure and computation guided engineering of a Lipase for Omega-3 fatty acid selectivity Moharana, T. R.; Rao, N. 10.1101/592063 — biochemistry — Posted on 2019-03-28 366 Resting networks and personality predict attack speed in social spiders Hunt, E. R.; Mi, B.; Geremew, R.; Fernandez, C.; Wong, B. M.; Pruitt, J. N.; Pinter-Wollman, N. 10.1101/591453 — animal behavior and cognition — Posted on 2019-03-28 367 ETFL: A formulation for flux balance models accounting for expression, thermodynamics, and resource allocation constraints SALVY, P.; Hatzimanikatis, V. 10.1101/590992 — systems biology — Posted on 2019-03-28 368 A general mathematical framework for understanding the behavior of heterogeneous stem cell regeneration Lei, J. 10.1101/592139 — systems biology — Posted on 2019-03-28 369 Hierarchy of connectivity-function relationship of the human cortex revealed through predicting activity across functional domains Wu, D.; Fan, L.; Song, M.; Wang, H.; Chu, C.; Yu, S.; Jiang, T. 10.1101/591776 — neuroscience — Posted on 2019-03-28 370 A sound-sensitive source of alpha oscillations in human non-primary auditory cortex Billig, A. J.; Herrmann, B.; Rhone, A. E.; Gander, P. E.; Nourski, K. V.; Snoad, B. F.; Kovach, C. K.; Kawasaki, H.; Howard, M. A.; Johnsrude, I. S. 10.1101/590323 — neuroscience — Posted on 2019-03-28 371 Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing Acharya, S.; Mishra, A.; Paul, D.; Ansari, A. H.; Azhar, M.; Sharma, N.; Aich, M.; Sinha, D.; Sharma, S.; Jain, S.; Ray, A.; Maiti, S.; Chakraborty, D. 10.1101/591263 — molecular biology — Posted on 2019-03-28 372 Islet Gene View - a tool to facilitate islet research Asplund, O.; Storm, P.; Ottosson-Laakso, E.; Krus, U.; Korsgren, O.; Mulder, H.; Renstrom, E.; Hansson, O.; Groop, L.; Prasad, R. B. 10.1101/435743 — molecular biology — Posted on 2019-03-28 373 Gut Microbiome Functional and Taxonomic Diversity within an Amazonian semi-nomadic hunter-gatherer group Conteville, L. C.; Oliveira-Ferreira, J.; Vicente, A. C. P. 10.1101/590034 — microbiology — Posted on 2019-03-28 374 Shared genetic background between children and adults with attention deficit/hyperactivity disorder Rovira, P.; Demontis, D.; Sanchez-Mora, C.; Zayats, T.; Klein, M.; Roth Mota, N.; Weber, H.; Garcia-Martinez, I.; Pagerols, M.; Vilar, L.; Arribas, L.; Richarte, V.; Corrales, M.; Fadeuilhe, C.; Bosch, R.; Espanol Martin, G.; Almos, P.; Doyle, A. E.; Grevet, E. H.; Grimm, O.; Halmoy, A.; Hoogman, M.; Hutz, M.; Jacob, C. P.; Kittel-Schneider, S.; Knappskog, P. M.; Lundervold, A.; Rivero, O.; Rovaris, D. L.; Salatino-Oliveira, A.; Santos da Silva, B.; Svirin, E.; Sprooten, E.; Strekalova, T.; ADHD Working Group of the Psychiatric Genomics Con, ; 23andMe Research team, ; Arias-Vasquez, A.; Sonu 10.1101/589614 — genetics — Posted on 2019-03-28 375 Single-molecule genome assembly of the Basket Willow, Salix viminalis, reveals earliest stages of sex chromosome expansion Almeida, P.; Proux-Wera, E.; Churcher, A.; Soler, L.; Dainat, J.; Pucholt, P.; Nordlund, J.; Martin, T.; Rönnberg-Wästljung, A. C.; Nystedt, B.; Berlin, S.; Mank, J. E. 10.1101/589804 — evolutionary biology — Posted on 2019-03-28 376 Unifying Gene Duplication, Loss, and Coalescence on Phylogenetic Networks Du, P.; Ogilvie, H.; Nakhleh, L. 10.1101/589655 — evolutionary biology — Posted on 2019-03-28 377 VIVA (VIsualization of VAriants): A VCF file visualization tool Tollefson, G. A.; Schuster, J.; Gelin, F.; Ragavendran, A.; Restrepo, I.; Stey, P.; Padbury, J.; Uzun, A. 10.1101/589879 — bioinformatics — Posted on 2019-03-28 378 Deep convolutional neural networks for predicting the quality of single protein structural models Hou, J.; Cao, R.; Cheng, J. 10.1101/590620 — bioinformatics — Posted on 2019-03-28 379 Exploration of interaction scoring criteria in the CANDO platform Falls, Z.; Mangione, W.; Schuler, J.; Samudrala, R. 10.1101/591578 — bioinformatics — Posted on 2019-03-28 380 Osmolyte homeostasis controls single-cell growth rate and maximum cell size of Saccharomyces cerevisiae Altenburg, T.; Goldenbogen, B.; Uhlendorf, J.; Klipp, E. 10.1101/586479 — systems biology — Posted on 2019-03-28 381 Identification of nitrogen-dependent QTL and underlying genes for root system architecture in hexaploid wheat Griffiths, M. D.; Atkinson, J. A.; Gardiner, L.-J.; Swarup, R.; Pound, M. P.; Wilson, M. H.; Bennett, M. J.; Wells, D. M. 10.1101/591529 — plant biology — Posted on 2019-03-28 382 CELL SPECIFIC REACTIVATION OF EPICARDIUM AT THE ORIGIN OF FIBRO-FATTY REMODELING OF THE ATRIAL MYOCARDIUM Suffee-Mosbah, N.; Moore-Morris, t.; Mougenot, n.; dilanaian, g.; berthet, m.; jagla, b.; Proukhnitzky, j.; leprince, p.; tregouet, d.; puceat, m.; hatem, s. 10.1101/589705 — pathology — Posted on 2019-03-28 383 Propagation of orientation selectivity in a spiking network model of layered primary visual cortex Merkt, B.; Schuessler, F.; Rotter, S. 10.1101/425694 — neuroscience — Posted on 2019-03-28 384 Monovision and the misperception of motion Burge, J.; Rodriguez-Lopez, V.; Dorronsoro, C. 10.1101/591560 — neuroscience — Posted on 2019-03-28 385 Specific Gut Microbiome Members are Associated with Distinct Immune Markers in Allogeneic Hematopoietic Stem Cell Transplantation Masche, A. C.; Kielsen, K.; Cilieborg, M. S.; Lund, O.; Holmes, S.; Aarestrup, F. M.; Muller, K. G.; Pamp, S. J. 10.1101/590893 — microbiology — Posted on 2019-03-28 386 Discovery of ongoing selective sweeps within Anopheles mosquito populations using deep learning Xue, A. T.; Schrider, D. R.; Kern, A. D.; Ag1000G Consortium, 10.1101/589069 — evolutionary biology — Posted on 2019-03-28 387 Apical transport of Crumbs maintains epithelial cell polarity Aguilar-Aragon, M.; Fletcher, G.; Thompson, B. J. 10.1101/592311 — developmental biology — Posted on 2019-03-28 388 Quantification of biomolecular dynamics inside real and synthetic nuclear pore complexes using time-resolved atomic force microscopy Stanley, G. J.; Akpinar, B.; Shen, Q.; Ellis Fisher, P. D.; Lusk, C. P.; Lin, C.; Hoogenboom, B. 10.1101/592303 — biophysics — Posted on 2019-03-28 389 Folate deficiency facilitates coordination of KDM6A with p53 in response to DNA damage Gao, J.; Zou, J.; Li, J.; Zhang, Y.; Qiao, L.; Wang, F.; Bao, Y.; Hu, J.; Zhang, T.; Xie, Q.; Liu, C. 10.1101/591768 — bioinformatics — Posted on 2019-03-28 390 Inhibition of mTORC1 signaling in aged rats counteracts the decline in muscle mass and reverses multiple parameters of muscle signaling associated with sarcopenia Joseph, G. A.; Wang, S.; Zhou, W.; Kimble, G.; Tse, H.; Eash, J. K.; Shavlakadze, T.; Glass, D. J. 10.1101/591891 — physiology — Posted on 2019-03-28 391 Rapid discovery of drug target engagement by isothermal shift assay Webb, K. J.; Ball, K. A.; Coleman, S. J.; Jacobsen, J.; Stowell, M.; Old, W. M. 10.1101/584656 — pharmacology and toxicology — Posted on 2019-03-28 392 A Robust Model of Gated Working Memory Strock, A.; Hinaut, X.; Rougier, N. P. 10.1101/589564 — neuroscience — Posted on 2019-03-28 393 Spectral Graph Theory of Brain Oscillations Raj, A.; Cai, C.; Xie, X.; Palacios, E.; Owen, J.; Mukherjee, P.; Nagarajan, S. 10.1101/589176 — neuroscience — Posted on 2019-03-28 394 Rapid and iterative genome editing in the zoonotic malaria parasite Plasmodium knowlesi: New tools for P. vivax research Mohring, F.; Hart, M. N.; Rawlinson, T. A.; Henrici, R.; Charleston, J. A.; Diez Benavente, E.; Patel, A.; Hall, J.; Almond, N.; Campino, S.; Clark, T. G.; Sutherland, C. J.; Baker, D. A.; Draper, S. J.; Moon, R. W. 10.1101/590976 — microbiology — Posted on 2019-03-28 395 Rhinovirus 2A is the predominant protease responsible for instigating the early block to gene expression encountered in infected cells Smart, D.; Filippi, I.; Smalley, B.; Davies, D.; McCormick, C. 10.1101/591032 — microbiology — Posted on 2019-03-28 396 Effects of carbon nanotubes and derivatives of graphene oxide on soil bacterial diversity Forstner, C.; Orton, T. G.; Wang, P.; Kopittke, P. M.; Dennis, P. G. 10.1101/591842 — microbiology — Posted on 2019-03-28 397 Gene content of the fish-hunting cone snail Conus consors Andreson, R.; Roosaare, M.; Kaplinski, L.; Laht, S.; Koressaar, T.; Lepamets, M.; Brauer, A.; Kukushkina, V.; Remm, M. 10.1101/590695 — genomics — Posted on 2019-03-28 398 A Gene Co-expression Network-based Analysis of Multiple Brain Tissues Reveals Novel Genes and Molecular Pathways Underlying Major Depression Gerring, Z. F.; Derks, E.; Major Depressive Disorder Working Group of the Psy, ; Gamazon, E. 10.1101/591693 — genetics — Posted on 2019-03-28 399 The p factor: Genetic analyses support a general dimension of psychopathology in childhood and adolescence Allegrini, A. G.; Cheesman, R.; Rimfeld, K.; Selzam, S.; Pingault, J.-B.; Eley, T.; Plomin, R. 10.1101/591354 — genetics — Posted on 2019-03-28 400 Family aggregation analysis reveals a heritable background of equine grass sickness (dysautonomia) Vincze, B.; Varga, M.; Gaspardy, A.; Kutasi, O.; Zenke, P.; Szenci, O.; Baska, F.; Bartels, A.; Spisak, S.; Solymosi, N. 10.1101/592253 — genetics — Posted on 2019-03-28 401 A triple-hybrid cross reveals new a hybrid incompatibility locus between D. melanogaster and D. sechellia Cooper, J. C.; Guo, P.; Bladen, J.; Phadnis, N. 10.1101/590588 — evolutionary biology — Posted on 2019-03-28 402 Parasites Acquired Beta Satellite DNAs from Hominid Hosts via Horizontal Gene Transfer Yang, J.; Zhou, Y.; Ma, G.; Zhang, X.; Guo, Y. 10.1101/589531 — evolutionary biology — Posted on 2019-03-28 403 Extreme heterogeneity in sex chromosome differentiation and dosage compensation in livebearers Darolti, I.; Wright, A. E.; Sandkam, B. A.; Morris, J.; Bloch, N. I.; Farre, M.; Fuller, R. C.; Bourne, G. R.; Larkin, D. M.; Breden, F.; Mank, J. E. 10.1101/589788 — evolutionary biology — Posted on 2019-03-28 404 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies Avila, P.; Fromhage, L.; Lehmann, L. 10.1101/454512 — evolutionary biology — Posted on 2019-03-28 405 Phylogenetic inference of changes in amino acid propensities with single-position resolution Klink, G. V.; Bazykin, G. A. 10.1101/589572 — evolutionary biology — Posted on 2019-03-28 406 Limits to Genomic Divergence Under Sexually Antagonistic Selection Kasimatis, K. R.; Ralph, P. L.; Phillips, P. C. 10.1101/591610 — evolutionary biology — Posted on 2019-03-28 407 The effects of the neonicotinoid imidacloprid on gene expression and DNA methylation in the buff-tailed bumblebee Bombus terrestris Bebane, P. S. A.; Hunt, B. J.; Pegoraro, M.; Jones, A. R. C.; Marshall, H.; Rosato, E.; Mallon, E. B. 10.1101/590091 — ecology — Posted on 2019-03-28 408 MASST: A Web-based Basic Mass Spectrometry Search Tool for Molecules to Search Public Data. Wang, M.; Jarmusch, A. K.; Vargas, F.; Aksenov, A. A.; Gauglitz, J.; Weldon, K.; Petras, D.; da Silva, R.; Quinn, R.; Melnik, A.; van der Hooft, J. J. J.; Rodriguez, A. M. C.; Nothias, L. F.; Aceves, C. M.; Panitchpakdi, M.; Brown, E.; Di Ottavio, F.; Sikora, N.; Elijah, E. O.; Labarta-Bajo, L.; Gentry, E. G.; Shalapour, S.; Kyle, K. E.; Puckett, S. P.; Watrous, J. D.; Carpenter, C. S.; Bouslimani, A.; Ernst, M.; Swafford, A. D.; Zuniga, E. I.; Balunas, M. J.; Klassen, J. L.; Loomba, R.; Knight, R.; Bandeira, N.; Dorrestein, P. C. 10.1101/591016 — bioinformatics — Posted on 2019-03-28 409 TreeCluster: clustering biological sequences using phylogenetic trees Balaban, M.; Moshiri, N.; Mai, U.; Mirarab, S. 10.1101/591388 — bioinformatics — Posted on 2019-03-28 410 PrankWeb: web server for ligand binding-site prediction and visualization Jendele, L.; Krivak, R.; Skoda, P.; Novotny, M.; Hoksza, D. 10.1101/590877 — bioinformatics — Posted on 2019-03-28 411 A Cas9 nanoparticle system with truncated Cas9 target sequences on DNA repair templates enhances genome targeting in diverse human immune cell types Nguyen, D. N.; Roth, T. L.; Li, J.; Chen, P. A.; Mamedov, M. M.; Vo, L. T.; Tobin, V.; Apathy, R.; Goodman, D.; Shifrut, E.; Bluestone, J. A.; Puck, J. M.; Szoka, F. C.; Marson, A. 10.1101/591719 — bioengineering — Posted on 2019-03-28 412 Moments reconstruction and local dynamic range compression of high order Superresolution optical fluctuation imaging Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S. 10.1101/500819 — bioengineering — Posted on 2019-03-28 413 Laminar Specific fMRI Reveals Directed Interactions in Distributed Networks During Language Processing Sharoh, D.; van Mourik, T.; Bains, L. J.; Segaert, K.; Weber, K.; Hagoort, P.; Norris, D. G. 10.1101/585844 — neuroscience — Posted on 2019-03-28 414 Online sensory feedback during active search improves tactile localization Fuchs, X.; Wulff, D. U.; Heed, T. 10.1101/590539 — neuroscience — Posted on 2019-03-28 415 Untangling intelligence, psychopathy, antisocial personality disorder, & conduct problems: A meta-analytic review Sanchez de Ribera, O.; Kavish, N.; Katz, I.; Boutwell, B. 10.1101/100693 — neuroscience — Posted on 2019-03-28 416 Cultivating in situ triggers growth of previously uncultivated microorganisms via a growth initiation factor in nature Jung, D.; Machida, K.; Nakao, Y.; Kindaichi, T.; Ohashi, A.; Aoi, Y. 10.1101/590653 — microbiology — Posted on 2019-03-28 417 Characterization of novel Chrysosporium morrisgordonii sp. nov., from bat white-nose syndrome (WNS) affected mines, northeastern United States Zhang, T.; Ren, P.; Li, X.; Chaturvedi, S.; Chaturvedi, V. 10.1101/591503 — microbiology — Posted on 2019-03-28 418 CoBATCH for high-throughput single-cell epigenomic profiling Wang, Q.; Xioong, H.; Ai, S.; Yu, X.; Liu, Y.; Zhang, J.; He, A. 10.1101/590661 — genomics — Posted on 2019-03-28 419 Functional genomics of a symbiotic community: shared traits in the olive fruit fly gut microbiota Blow, F.; Gioti, A.; Goodhead, I. B.; Kalyva, M.; Kampouraki, A.; Vontas, J.; Darby, A. C. 10.1101/590489 — evolutionary biology — Posted on 2019-03-28 420 Predicting primary production in the southern California Current Ecosystem from chlorophyll, nutrient concentrations, and irradiance Stukel, M.; Goericke, R.; Landry, M. R. 10.1101/590240 — ecology — Posted on 2019-03-28 421 Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility Nishimura, K.; Dioguardi, E.; Nishio, S.; Villa, A.; Han, L.; Matsuda, T.; Jovine, L. 10.1101/591966 — biophysics — Posted on 2019-03-28 422 Reinforcement regulates timing variability in thalamus Wang, J.; Hosseini, E.; Meirhaeghe, N.; Akkad, A.; Jazayeri, M. 10.1101/583328 — neuroscience — Posted on 2019-03-28 423 MiR-218: A Molecular Switch and Potential Biomarker of Susceptibility to Stress Torres-Berrio, A.; Nouel, D.; Cuesta, S.; Parise, E. M.; Restrepo-Lozano, J. M.; Larochelle, P.; Nestler, E. J.; Flores, C. 10.1101/589325 — neuroscience — Posted on 2019-03-28 424 White Matter Extension of the Melbourne Children’s Regional Infant Brain Atlas: M-CRIB-WM Yao, S. H. W.; Yang, J. Y.-M.; Alexander, B.; Wu, M. H.; Kelly, C. E.; Ball, G.; Seal, M. L.; Anderson, P. J.; Doyle, L. W.; Cheong, J. L. Y.; Spittle, A. J.; Thompson, D. K. 10.1101/590596 — neuroscience — Posted on 2019-03-28 425 Brain connectivity measures improve modeling of functional outcome after acute ischemic stroke Ktena, S. I.; Schirmer, M.; Etherton, M. R.; Giese, A.-K.; Tuozzo, C.; Mills, B. B.; Rueckert, D.; Wu, O.; Rost, N. S. 10.1101/590497 — neuroscience — Posted on 2019-03-28 426 Damage to the Right Insula Disrupts the Perception of Affective Touch Kirsch, L. P.; Besharati, S.; Papadaki, C.; Crucianelli, L.; Bertagnoli, S.; Ward, N.; Moro, V.; Jenkinson, P. M.; Fotopoulou, A. 10.1101/592014 — neuroscience — Posted on 2019-03-28 427 The complete chloroplast genome of Chinese medicine (Psoralea corylifolia Linn): Molecular Structures, Barcoding analysis, and Phylogenetic Analysis Tan, W.; Gao, H.; Zhang, H.; Yu, X.; Tian, X.; Jiang, W.; Zhou, K. 10.1101/587758 — genomics — Posted on 2019-03-28 428 Genetic evaluation modeling of the Tunisian dairy cattle: assessment of the test-day model (TDM) and lactation model (L305) in accordance to the flock size ressaissi, y.; Ben Hamouda, M. 10.1101/589523 — genetics — Posted on 2019-03-28 429 Divergent mitochondrial and nuclear OXPHOS genes are candidates for genetic incompatibilities in Ficedula Flycatchers van der Heijden, E.; McFarlane, E.; van der Valk, T.; Qvarnstrom, A. 10.1101/588756 — evolutionary biology — Posted on 2019-03-28 430 Replicated anthropogenic hybridisations reveal parallel patterns of admixture in marine mussels. Simon, A.; Arbiol, C.; Nielsen, E. E.; Couteau, J.; Sussarellu, R.; Burgeot, T.; Bernard, I.; Coolen, J. W. P.; Lamy, J.-B.; Robert, S.; Skazina, M.; Strelkov, P.; Queiroga, H.; Cancio, I.; Welch, J. J.; Viard, F.; Bierne, N. 10.1101/590737 — evolutionary biology — Posted on 2019-03-28 431 Estimating spatially and temporally complex range dynamics when detection is imperfect Rushing, C.; Royle, J. A.; Ziolkowski, D. J.; Pardieck, K. L. 10.1101/586909 — ecology — Posted on 2019-03-28 432 A model of collective behavior based purely on vision Bastien, R.; Romanczuk, P. 10.1101/589663 — animal behavior and cognition — Posted on 2019-03-28 433 Conformational gating in ammonia lyases Lambrughi, M.; Sanader Marsic, Z.; Saez-Jimenez, V.; Mapelli, V.; Olsson, L.; Papaleo, E. 10.1101/583088 — biophysics — Posted on 2019-03-28 434 NanoDJ: A Dockerized Jupyter Notebook for Interactive Oxford Nanopore MinION Sequence Manipulation and Genome Assembly Rodriguez-Perez, H.; Tamara, H.-B.; Lorenzo-Salazar, J. M.; Roda-Garcia, J. L.; Perez-Gonzalez, C. J.; Colebrook, M.; Flores, C. 10.1101/586842 — bioinformatics — Posted on 2019-03-28 435 Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2 Fred, S. M.; Laukkanen, L.; Vesa, L.; Goos, H.; Cardon, I.; Moliner, R.; Maritzen, T.; Varjosalo, M.; Casarotto, P. C.; Castren, E. 10.1101/591909 — pharmacology and toxicology — Posted on 2019-03-28 436 Precision timing with alpha-beta oscillatory coupling: stopwatch or motor control? Kononowicz, T. W.; Sander, T.; Van Rijn, H.; van Wassenhove, V. 10.1101/591933 — neuroscience — Posted on 2019-03-28 437 Genotype 1 Japanese encephalitis virus predominates in nature in China Shao, N.; Fu, S.; Li, F.; Zhang, W.; Wang, Q.; Lei, W.; He, Y.; Cao, Y.; liang, G.; Wang, H. 10.1101/591339 — molecular biology — Posted on 2019-03-28 438 Identification of pathogen genomic differences that impact human immune response and disease during Cryptococcus neoformans infection Gerstein, A. C.; Jackson, K. M.; McDonald, T. R.; Wang, Y.; Lueck, B. D.; Bohjanen, S.; Smith, K. D.; Akampurira, A.; Meya, D. B.; Xue, C.; Boulware, D. R.; Nielsen, K. 10.1101/592212 — genetics — Posted on 2019-03-28 439 Spatio-temporal distribution of Spiroplasma infections in the tsetse fly (Glossina fuscipes fuscipes) in northern Uganda Schneider, D. I.; Saarman, N.; Onyango, M. G.; Hyseni, C.; Opiro, R.; Echodu, R.; O'Neill, M.; Bloch, D.; Vigneron, A.; Johnson, T. J.; Dion, K.; Weiss, B. L.; Opiyo, E.; Caccone, A.; Aksoy, S. 10.1101/591321 — epidemiology — Posted on 2019-03-28 440 Heroin Type, Injecting Behavior, and HIV Transmission. A Simulation Model of HIV Incidence and Prevalence Bobashev, G.; Mars, S.; Murphy, N.; Dreisbach, C.; Zule, W.; Ciccarone, D. 10.1101/591180 — epidemiology — Posted on 2019-03-28 441 Knowledge and awareness of cervical cancer in Southwestern Ethiopia is lacking: a descriptive analysis Saleem, A.; Bekele, A.; Fitzpatrick, M. B.; Mahmoud, E. A.; Lin, A. W.; Velasco, H. E.; Rashed, M. M. 10.1101/592196 — epidemiology — Posted on 2019-03-28 442 Dietary acculturation of Asian and the Middle East and North African region immigrants to Saudi Arabia: healthy or unhealthy acquired nutritional behavior? Al Zeidan, R.; Tharkar, S.; Hersi, A.; Ullah, A. 10.1101/591230 — epidemiology — Posted on 2019-03-28 443 Efficiency of protein synthesis inhibition depends on tRNA and codon compositions Rudorf, S. 10.1101/592204 — cell biology — Posted on 2019-03-28 444 Facile assembly of an affordable miniature multicolor fluorescence microscope made of 3D-printed parts enables detection of single cells Tristan-Landin, S. B.; Gonzalez-Suarez, A. M.; Jimenez-Valdes, R. J.; Garcia-Cordero, J. L. 10.1101/592170 — bioengineering — Posted on 2019-03-28 445 Nitro-fatty acids formation in Virgin Olive Oil during gastric digestion and its relationship to cultivar and fruit ripening Sanchez-Calvo, B.; Mastrogiovanni, M.; Conde-Innamorato, P.; Arias-Sibillotte, M.; Trostchansky, A.; Rubbo, H. 10.1101/592147 — plant biology — Posted on 2019-03-28 446 Library preparation and sequencing platform introduces bias in metagenomics characterisation of microbial communities Poulsen, C. S.; Aarestrup, F. M.; Ekstrom, C. T.; Pamp, S. J. 10.1101/592154 — microbiology — Posted on 2019-03-28 447 Isolation of lactic acid bacteria capable of reducing environmental alkyl and fatty acid hydroperoxides, and the effect of their oral administration on oxidative-stressed nematodes and rats Watanabe, A.; Niimura, Y.; Yamaguchi, T.; Murota, K. 10.1101/592162 — microbiology — Posted on 2019-03-28 448 Multiscale analysis of acne connects molecular subnetworks with disease status Hall, J. B.; Divaraniya, A. A.; Lee, H.-C.; Becker, C. E.; McCauley, B.; Glowe, P. K.; Sebra, R.; Pavel, A. B.; Singer, G.; Nelson, A.; Thiboutot, D.; Marmur, E.; Schadt, E. E.; Zeichner, J.; Guttman-Yassky, E.; Kidd, B. A.; Dudley, J. T. 10.1101/587857 — systems biology — Posted on 2019-03-28 449 Functional relevance of dual olfactory bulb in olfactory coding Kuruppath, P.; Belluscio, L. 10.1101/588996 — neuroscience — Posted on 2019-03-28 450 Mechanics of DNA Replication and Transcription Guide the Asymmetric Distribution of RNAPol2 and New Nucleosomes on Replicated Daughter Genomes Ziane, R.; Camasses, A.; Radman-Livaja, M. 10.1101/553669 — molecular biology — Posted on 2019-03-28 451 Single cell expression variability in highly homogeneous populations of human cells is widespread, is heritable, and implies cell function Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J. 10.1101/574426 — genomics — Posted on 2019-03-28 452 Discovery of Hierarchical Representations for Efficient Planning Tomov, M.; Yagati, S.; Kumar, A.; Yang, W.; Gershman, S. 10.1101/499418 — neuroscience — Posted on 2019-03-28 453 Predicting the occurrence of variants in RAG1 and RAG2 Lawless, D.; Lango Allen, H.; Thaventhiran, J.; Rare Diseases Consortium, N. B.; Hodel, F.; Fellay, J.; Walter, J. E.; Anwar, R.; Savic, S. 10.1101/272609 — genomics — Posted on 2019-03-28 454 Estimating prevalence for limb-girdle muscular dystrophy based on public sequencing databases Liu, W.; Pajusalu, S.; Lake, N. J.; Zhou, G.; Ioannidis, N.; Mittal, P.; Johnson, N. E.; Weihl, C. C.; Williams, B. A.; Albrecht, D. E.; Rufibach, L. E.; Lek, M. 10.1101/502708 — epidemiology — Posted on 2019-03-28 455 Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC Messerschmidt, C.; Obermayer, B.; Klinghammer, K.; Ochsenreither, S.; Treue, D.; Stenzinger, A.; Glimm, H.; Fröhling, S.; Kindler, T.; Brandts, C. H.; Schulze-Osthoff, K.; Weichert, W.; Tinhofer, I.; Klauschen, F.; Keilholz, U.; Beule, D.; Rieke, D. T. 10.1101/586396 — cancer biology — Posted on 2019-03-28 456 Synthetic 5 UTRs can either up- or down-regulate expression upon RBP binding Katz, N.; Cohen, R.; Solomon, O.; Kaufmann, B.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R. 10.1101/174888 — synthetic biology — Posted on 2019-03-28 457 Enhancer-promoter association determines Sox2 transcription regulation in mouse pluripotent cells Huang, L.; Li, Q.; Huang, Q.; Kong, S.; Zhu, X.; Peng, Y.; Zhang, Y. 10.1101/590745 — molecular biology — Posted on 2019-03-28 458 Decorating Microbially Produced Protein Nanowires with Peptide Ligands Ueki, T.; Walker, D. J.; Tremblay, P.-L.; Nevin, K. P.; Ward, J. E.; Woodard, T. L.; Nonnenmann, S. S.; Lovley, D. R. 10.1101/590224 — synthetic biology — Posted on 2019-03-28 459 Metabolite sequestration enables rapid recovery from nutrient depletion Hartline, C.; Mannan, A. A.; Zhang, F.; Oyarzun, D. A. 10.1101/590943 — systems biology — Posted on 2019-03-27 460 Feedback control promotes synchronisation of the cell-cycle across a population of yeast cells Perrino, G.; Fiore, D.; Napolitano, S.; Galdi, F.; La Regina, A.; di Bernardo, M.; di Bernardo, D. 10.1101/590844 — synthetic biology — Posted on 2019-03-27 461 Phase space characterization for gene circuit design Munoz Silva, M. A.; Matute, T.; Nunez, I.; Valdes, A.; Ruiz, C.; Vidal Pena, G.; Federici, F.; Rudge, T. J. 10.1101/590299 — synthetic biology — Posted on 2019-03-28 462 Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+ Yong, J.; Bischof, H.; Siirin, M.; Murphy, A. N.; Malli, R.; Kaufman, R. J. 10.1101/591685 — cell biology — Posted on 2019-03-27 463 Macro-to-nano scale investigation of the acorn barnacle Semibalanus balanoides: correlative imaging, biological form and function, and bioinspiration Mitchell, R. L.; Coleman, M.; Davies, P.; North, L.; Pope, E.; Pleydell-Pearce, C.; Harris, W.; Johnston, R. 10.1101/590158 — systems biology — Posted on 2019-03-27 464 Differential expression of the T cell inhibitor TIGIT in Glioblastoma and Multiple Sclerosis Lucca, L. E.; Lerner, B. A.; DeBartolo, D.; Park, C.; Ponath, G.; Raddassi, K.; Hafler, D. A.; Pitt, D. 10.1101/591131 — immunology — Posted on 2019-03-27 465 Integration of pathway, cellular and genetic context reveals principles of synthetic lethality that affect reproducibility Ku, A. A.; Kongara, S.; Hu, H.-M.; Zhao, X.; Wu, D.; McCormick, F.; Balmain, A.; Bandyopadhyay, S. 10.1101/591677 — cancer biology — Posted on 2019-03-27 466 Thermodynamic impacts of combinatorial mutagenesis on protein conformational stability: precise, high-throughput measurement by Thermofluor Carter, C. W.; Weinreb, V.; Weinreb, G.; Chandrasekaran, S. N.; Das, J.; Dokholyan, N. 10.1101/591495 — biophysics — Posted on 2019-03-27 467 Addressable, \"Packet-Based\" Intercellular Communication through Plasmid Conjugation Marken, J. P.; Murray, R. M. 10.1101/591552 — synthetic biology — Posted on 2019-03-27 468 Phospho-tuning immunity through Denisovan, modern human, and mouse TNFAIP3 gene variants Zammit, N. W.; Siggs, O. M.; Gray, P.; Horikawa, K.; Daley, S. R.; Langley, D. B.; Cultrone, D.; Malle, E. K.; Walters, S. N.; Villanueva, J. E.; Warren, J.; Russell, A.; Cowley, M. J.; Gayevskiy, V.; Dinger, M. E.; Loetsch, C.; King, C.; Brink, R.; Zahra, D.; Chaudhri, G.; Karupiah, G.; Whittle, B.; Roots, C.; Bertram, E.; Yamada, M.; Jeelall, Y.; Enders, A.; Clifton, B. E.; Mabbitt, P. D.; Jackson, C. J.; Watson, S. R.; Jenne, C. N.; Lanier, L. L.; Wiltshire, T.; Spitzer, M. H.; Nolan, G. P.; Schmitz, F.; Aderem, A.; Porebski, B. T.; Buckle, A. M.; Abbott, D. W.; Ziegler, J. B.; Craig, M. E. 10.1101/589507 — immunology — Posted on 2019-03-27 469 The transcriptional regulator Id2 is critical for adipose-resident regulatory T cell differentiation, survival and function Frias, A. B.; Hyzny, E. J.; Buechel, H. M.; Beppu, L.; Xie, B.; Jurczak, M. J.; D'Cruz, L. M. 10.1101/589994 — immunology — Posted on 2019-03-27 470 Seeing versus Knowing: The Temporal Dynamics of Real and Implied Colour Processing in the Human Brain Teichmann, L.; Grootswagers, T.; Carlson, T.; Rich, A. 10.1101/369926 — neuroscience — Posted on 2019-03-27 471 Exposure to maternal obesity per se programs sex-differences in pancreatic islets of the offspring Nicholas, L. M.; Nagao, M.; Kusinski, L. C.; Fernandez-Twinn, D. S.; Eliasson, L.; Ozanne, S. E. 10.1101/591586 — physiology — Posted on 2019-03-27 472 Computing Hubs in the Hippocampus and Cortex Clawson, W. P.; Vicente, A. F.; Ferraris, M.; Bernard, C.; Battaglia, D.; Quilichini, P. P. 10.1101/513424 — neuroscience — Posted on 2019-03-27 473 Familiar neighbors, but not relatives, enhance fitness in a territorial mammal Siracusa, E.; Boutin, S.; Dantzer, B.; Lane, J. E.; Coltman, D. W.; McAdam, A. G. 10.1101/589002 — evolutionary biology — Posted on 2019-03-27 474 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C. 10.1101/589366 — bioinformatics — Posted on 2019-03-27 475 Expression and distribution of Trophoblast Glycoprotein in the mouse retina Wakeham, C. M.; Ren, G.; Morgans, C. W. 10.1101/590216 — neuroscience — Posted on 2019-03-27 476 Identification of PKCα-dependent phosphoproteins in mouse retina Wakeham, C. M.; Wilmarth, P. A.; Cunliffe, J. M.; Klimek, J. E.; Ren, G.; David, L. L.; Morgans, C. W. 10.1101/589184 — neuroscience — Posted on 2019-03-27 477 Quantitative assessment of anti-gravity reflexes to evaluate vestibular dysfunction in rats Martins-Lopes, V.; Bellmunt, A.; Greguske, E. A.; Maroto Ferrer, A. F.; Boadas-Vaello, P.; Llorens, J. 10.1101/590257 — neuroscience — Posted on 2019-03-27 478 Transcriptome-based prediction of complex traits in maize Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H. 10.1101/587121 — genetics — Posted on 2019-03-27 479 The optimal discovery procedure for significance analysis of general gene expression studies Bass, A. J.; Storey, J. D. 10.1101/571992 — bioinformatics — Posted on 2019-03-27 480 MCT4 is a high affinity transporter capable of exporting lactate in high-lactate environments Contreras-Baeza, Y.; Sandoval, P. Y.; Alarcon, R.; Galaz, A.; Cortes-Molina, F.; Alegria, K.; Baeza-Lehnert, F.; Arce-Molina, R.; Guequen, A.; Flores, C. A.; San Martin, A. A.; Barros, L. F. 10.1101/586966 — physiology — Posted on 2019-03-27 481 Mammillothalamic disconnection alters hippocampo-cortical oscillatory activity and microstructure: Implications for diencephalic amnesia Dillingham, C. M.; Milczarek, M. M.; Perry, J. C.; Frost, B. E.; Parker, G. D.; Assaf, Y.; Sengpiel, F.; O'Mara, S. M.; Vann, S. 10.1101/590901 — neuroscience — Posted on 2019-03-27 482 Heterogeneous profiles of coupled sleep oscillations in human hippocampus Cox, R.; Ruber, T.; Staresina, B. P.; Fell, J. 10.1101/589978 — neuroscience — Posted on 2019-03-27 483 VarSight: Prioritizing Clinically Reported Variants with Binary Classification Algorithms Holt, J. M.; Wilk, B.; Birch, C. L.; Brown, D. M.; Gajapathy, M.; Moss, A. C.; Sosonkina, N.; Wilk, M. A.; Anderson, J. A.; Harris, J. M.; Kelly, J. M.; Shaterferdosian, F.; Uno-Antonison, A. E.; Weborg, A.; Undiagnosed Diseases Network, ; Worthey, E. A. 10.1101/532440 — bioinformatics — Posted on 2019-03-27 484 Discrete and Continuous Cell Identities of the Adult Murine Striatum Stanley, G.; Gokce, O.; Malenka, R. C.; Sudhof, T. C.; Quake, S. R. 10.1101/591396 — neuroscience — Posted on 2019-03-27 485 Orchestrating Single-Cell Analysis with Bioconductor Amezquita, R. A.; Carey, V. J.; Carpp, L. N.; Geistlinger, L.; Lun, A. T.; Marini, F.; Rue-Albrecht, K.; Risso, D.; Soneson, C.; Waldron, L.; Pages, H.; Smith, M.; Huber, W.; Morgan, M.; Gottardo, R.; Hicks, S. C. 10.1101/590562 — genomics — Posted on 2019-03-27 486 APPLES: Distance-based Phylogenetic Placement for Scalable and Assembly-free Sample Identification Balaban, M.; Sarmashghi, S.; Mirarab, S. 10.1101/475566 — bioinformatics — Posted on 2019-03-27 487 Freshwater Adaptation at the Molecular Scale in the Unique Sponges of Lake Baikal Kenny, N. J.; Plese, B.; Riesgo, A.; Itskovich, V. B. 10.1101/416230 — zoology — Posted on 2019-03-27 488 Electroporation characteristics of human primary T cells Aksoy, P.; Aksoy, B. A.; Czech, E.; Hammerbacher, J. 10.1101/466243 — immunology — Posted on 2019-03-27 489 Aboave-Weaire’s law in epithelia results from an angle constraint in contiguous polygonal lattices Vetter, R.; Kokic, M.; Gomez, H.; Hodel, L.; Gjeta, B.; Iannini, A.; Villa-Fombuena, G.; Casares, F.; Iber, D. 10.1101/591461 — biophysics — Posted on 2019-03-27 490 Automated quantification of synaptic boutons reveals their 3D distribution in the insect mushroom body Cabirol, A.; Haase, A. 10.1101/589770 — neuroscience — Posted on 2019-03-27 491 The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor Coe, E. A.; Tan, J. Y.; Shapiro, M.; Louphrasitthiphol, P.; Bassett, A. R.; Marques, A. C.; Goding, C. R.; Vance, K. W. 10.1101/591065 — cancer biology — Posted on 2019-03-27 492 AMPK-independent LKB1 activity is required for efficient epithelial ovarian cancer metastasis Buensuceso, A.; Ramos Valdes, Y.; DiMattia, G. E.; Shepherd, T. 10.1101/591073 — cancer biology — Posted on 2019-03-27 493 Hippo pathway effectors YAP1/TAZ induce a EWS-FLI1-opposing gene signature and associate with disease progression in Ewing Sarcoma Rodriguez-Nunez, P.; Romero-Perez, L.; Amaral, A. T.; Puerto-Camacho, P.; Jordan, C.; Grunewald, T.; Marcilla, D.; de Alava, E.; Diaz-Martin, J. 10.1101/589648 — cancer biology — Posted on 2019-03-27 494 Molecular physiology of chemical defenses in a poison frog Caty, S. N.; Alvarez-Buylla, A.; Byrd, G. D.; Vidoudez, C.; Roland, A. B.; Tapia, E. E.; Bodnik, B.; Trauger, S. A.; Coloma, L. A.; O'Connell, L. A. 10.1101/591115 — physiology — Posted on 2019-03-27 495 Detecting nanoscale distribution of protein pairs by proximity-dependent super-resolution microscopy Lutz, T.; Kaufhold, W. T.; Clowsley, A. H.; Meletiou, A.; Di Michele, L.; Soeller, C. 10.1101/591081 — molecular biology — Posted on 2019-03-27 496 A conserved acidic cluster motif in SERINC5 confers resistance to antagonism by HIV-1 Nef Stoneham, C.; Ramirez, P. W.; Singh, R.; Suarez, M.; Debray, A.; Lim, C.; Jia, X.; Xiong, Y.; Guatelli, J. 10.1101/590646 — microbiology — Posted on 2019-03-27 497 Minimisation of surface energy drives apical epithelial organisation and gives rise to Lewis’ law Kokic, M.; Iannini, A.; Villa Fombuena, G.; Casares, F.; Iber, D. 10.1101/590729 — biophysics — Posted on 2019-03-27 498 A Chemical Probe of CARM1 Alters Epigenetic Plasticity against Breast Cancer Cell Invasion Cai, X.-C.; Zhang, T.; Kim, E.-j.; Jiang, M.; Wang, K.; Wang, J.; Chen, S.; Zhang, N.; Wu, H.; Li, F.; dela Sena, C. C.; Zheng, H.; Vivcharuk, V.; Niu, X.; Zheng, W.; Lee, J. P.; Chen, Y.; Barsyte, D.; Szewczyk, M.; Hajian, T.; Ibanez, G.; Dong, A.; Dombrovsky, L.; Zhang, Z.; Deng, H.; Min, J.; Arrowsmith, C. H.; Mazutis, L.; Shi, L.; Vedadi, M.; Brown, P. J.; Xiang, J.; Qin, L.-X.; Xu, W.; Luo, M. 10.1101/591164 — biochemistry — Posted on 2019-03-27 499 Geochemical and metagenomic characterization of Jinata Onsen, a Proterozoic-analog hot spring, reveals novel microbial diversity including iron-tolerant phototrophs and thermophilic lithotrophs Ward, L. M.; Idei, A.; Nakagawa, M.; Ueno, Y.; Fischer, W. W.; McGlynn, S. E. 10.1101/428698 — microbiology — Posted on 2019-03-27 500 Sumoylation regulates central spindle protein dynamics during chromosome segregation in oocyte Pelisch, F.; Bel Borja, L.; Jaffray, E. G.; Hay, R. T. 10.1101/584763 — cell biology — Posted on 2019-03-27 501 Homology-guided re-annotation improves the gene models of the alloploid Nicotiana benthamiana Kourelis, J.; Kaschani, F.; Grosse-Holz, F. M.; Homma, F.; Kaiser, M.; van der Hoorn, R. A. L. 10.1101/373506 — plant biology — Posted on 2019-03-27 502 Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and regulate behavioral odor discrimination McLachlan, A. D.; Wong, J. Y. H.; Wan, B. A.; O'Kane, C. J.; Montagnese, M.; Zhang, S. W.; Masuda-Nakagawa, L. M. 10.1101/295659 — neuroscience — Posted on 2019-03-27 503 A likelihood-free estimator of population structure bridging admixture models and principal components analysis Cabreros, I.; Storey, J. D. 10.1101/240812 — genomics — Posted on 2019-03-27 504 Unintended inhibition of protein function using GFP nanobodies in human cells Kuey, C.; Larocque, G.; Clarke, N. I.; Royle, S. J. 10.1101/590984 — cell biology — Posted on 2019-03-27 505 Conformational resolution of nucleotide cycling and effector interactions for multiple small GTPases in parallel Killoran, R. C.; Smith, M. J. 10.1101/577437 — biochemistry — Posted on 2019-03-27 506 Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress Hanna, N.; Burdet, F.; Melotti, A.; Bosmani, C.; Kicka, S.; Hilbi, H.; Cosson, P.; Pagni, M.; Soldati, T. 10.1101/590810 — systems biology — Posted on 2019-03-27 507 Expression and distribution of Trophoblast Glycoprotein in the mouse retina Wakeham, C. M.; Ren, G.; Morgans, C. W. 10.1101/590216 — neuroscience — Posted on 2019-03-27 508 Two accessory proteins govern MmpL3 mycolic acid transport in mycobacteria Fay, A.; Czudnochowski, N.; Rock, J.; Johnson, J.; Krogan, N.; Rosenberg, O.; Glickman, M. 10.1101/581447 — microbiology — Posted on 2019-03-27 509 WHO child growth standards for Pygmies: one size fits all? Fa, J. E.; Funk, S. M.; Guerra, B. P.; Ickowitz, A.; Poni, N. A.; Abdou, M. A.; Sibama, Y. H.; Penda, R.; Brull, G. R.; Abossolo, M.; Martin, E. A.; Okale, R.; Ze, B. A.; Carrion, A. M.; Sebastian, C. G.; de Loizaga Garcia, C. R.; Salazar, F. L.-R.; Amazia, H.; Reyes, I. A.; Exposito, R. S. 10.1101/591172 — scientific communication and education — Posted on 2019-03-27 510 The fungal endophyte Fusarium solani provokes differential effects on the energy balance of two Lotus species Nieva, A. S.; Vilas, J. M.; Garriz, A.; Maiale, S. J.; Menendez, A. B.; Erban, A.; Kopka, J.; Ruiz, O. A. 10.1101/588400 — microbiology — Posted on 2019-03-27 511 M. leprae infects human keratinocytes via the interaction of laminin-5 with α-dystroglycan, integrin-β1, or -β4. Jin, S.-H.; Kim, S.-K.; Lee, S.-B. 10.1101/591313 — microbiology — Posted on 2019-03-27 512 Rapidly increasing prevalence of overweight and obesity in older Ghanaian adults from 2007-2015: evidence from WHO-SAGE Waves 1 & 2 Lartey, S. T.; Magnussen, C. G.; Si, L.; Boateng, G. O.; de Graaff, B.; Biritwum, R. B.; Minicuci, N.; Kowal, P.; Blizzard, L.; Palmer, A. J. 10.1101/591222 — epidemiology — Posted on 2019-03-27 513 A systematic evaluation of neural morphology representations forcell type discrimination Laturnus, S.; Kobak, D.; Berens, P. 10.1101/591370 — neuroscience — Posted on 2019-03-27 514 Effect of progesterone on Candida albicans biofilm formation under acidic conditions: a transcriptomic analysis Goncalves, B.; Bernardo, R.; Wang, C.; Pedro, N.; Butler, G.; Azeredo, J.; Henriques, M.; Mira, N.; Silva, S. 10.1101/591347 — microbiology — Posted on 2019-03-27 515 Intermolecular interactions play a role in the distribution and transport of charged contrast agents in a cartilage model Söderman, O.; Algotsson, J.; Jönsson, P.; Forsman, J.; Topgaard, D. 10.1101/591255 — biophysics — Posted on 2019-03-27 516 Bioactivity-guided isolation of rosmarinic acid as a principle bioactive compound from the butanol extract of Isodon rugosus against pea aphid, Acyrthosiphon pisum Khan, S.; Taning, C. N. T.; Bonneure, E.; Mangelinckx, S.; Smagghe, G.; Ahmad, R.; Fatima, N.; Asif, M.; Shah, M. M. 10.1101/591271 — plant biology — Posted on 2019-03-27 517 Evaluation of the geographical utility of Eastern Russells viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity Chaisakul, J.; Sookprasert, N.; Harrison, R. A.; Chaiyabutr, N.; Chanhome, L.; Casewell, N. R. 10.1101/591305 — pharmacology and toxicology — Posted on 2019-03-27 518 Multicenter preclinical studies as an innovative method to enhance translation: a systematic review of published studies Hunniford, V. T.; Grudniewicz, A.; Fergusson, D. A.; Grigor, E.; Lansdell, C.; Lalu, M. 10.1101/591289 — epidemiology — Posted on 2019-03-27 519 Viral infection overcomes ineffectiveness of anti-tumoral CD8+ T cell mediated cytotoxicity Zhou, F.; Kardash, J.; Bhat, H.; Duhan, V.; Friedrich, S.; Bezgovsek, J.; Kalkavan, H.; Bergerhausen, M.; Schiller, M.; Machlah, Y.; Brandenburg, T.; Hardt, C.; Krolik, M.; Flatz, L.; Lang, P.; Lang, K. 10.1101/591198 — immunology — Posted on 2019-03-27 520 Ethanolic extract of Ocimum sanctum leaves reduced invasion and matrix metalloproteinase activity of head and neck cancer cell lines Utispan, K.; Niyomtham, N.; Yingyongnarongkul, B.-e.; Koontongkaew, S. 10.1101/591214 — cancer biology — Posted on 2019-03-27 521 Properties of individual hippocampal synapses influencing NMDA-receptor activation by spontaneous neurotransmission. Metzbower, S. R.; Joo, Y.; Benavides, D. R.; Blanpied, T. A. 10.1101/590141 — neuroscience — Posted on 2019-03-27 522 The WT1-like transcription factor Klumpfuss maintains lineage commitment in the intestine Korzelius, J.; Ronnen-Oron, T.; Baldauf, M.; Meier, E.; Sousa-Victor, P.; Jasper, H. 10.1101/590885 — developmental biology — Posted on 2019-03-27 523 Structural determinants of microtubule minus end preference in CAMSAP CKK domains Atherton, J.; Luo, Y.; Xiang, S.; Yang, C.; Jiang, K.; Stangier, M.; Vemu, A.; Cook, A. D.; Wang, S.; Roll-Mecak, A.; Steinmetz, M. O.; Akhmanova, A.; Baldus, M.; Moores, C. 10.1101/586230 — biophysics — Posted on 2019-03-27 524 The structure of an injectisome export gate demonstratesconservation of architecture in the core export gatebetween flagellar and virulence type three secretionsystems Johnson, S.; Kuhlen, L.; Deme, J.; Abrusci, P.; Lea, S. M. 10.1101/590273 — biochemistry — Posted on 2019-03-27 525 Contribution of PSD-95 protein to reward location memory Caly, A.; Sliwinska, M.; Ziolkowska, M.; Lukasiewicz, K.; Pagano, R.; Nowacka, A.; Borczyk, M.; Radwanska, K. 10.1101/590109 — neuroscience — Posted on 2019-03-27 526 Identification of PKC -dependent phosphoproteins in mouse retina Wakeham, C. M.; Wilmarth, P. A.; Cunliffe, J. M.; Klimek, J. E.; Ren, G.; David, L. L.; Morgans, C. W. 10.1101/589184 — neuroscience — Posted on 2019-03-27 527 Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules Rodriguez-Garcia, R.; Volkov, V. A.; Chen, C.-Y.; Katrukha, E. A.; Olieric, N.; Aher, A.; Grigoriev, I.; Preciado Lopez, M.; Steinmetz, M. O.; Kapitein, L. C.; Koenderink, G.; Dogterom, M.; Akhmanova, A. 10.1101/590869 — cell biology — Posted on 2019-03-27 528 A Synergistic Anti-Cancer FAK and HDAC Inhibitor Combination Discovered by a Novel Chemical-Genetic High Content Phenotypic Screen Dawson, J. C.; Serrels, B.; Byron, A.; Muir, M.; Makda, A.; Garcia-Munoz, A.; von Kriegsheim, A.; Carragher, N. O.; Frame, M. C. 10.1101/590802 — cancer biology — Posted on 2019-03-27 529 Cryo-EM of dynein microtubule-binding domains shows how an axonemal dynein distorts the microtubule Lacey, S. E.; He, S.; Scheres, S. H. W.; Carter, A. P. 10.1101/590786 — molecular biology — Posted on 2019-03-27 530 Single chromosome gains can function as metastasis suppressors and metastasis promoters Vasudevan, A.; Baruah, P. S.; Smith, J. C.; Wang, Z.; Sayles, N. M.; Andrews, P.; Kendall, J.; Chunduri, N. K.; Levy, D.; Wigler, M.; Storchova, Z.; Sheltzer, J. M. 10.1101/590547 — cancer biology — Posted on 2019-03-27 531 Observing an antisense drug complex in intact human cells by in-cell NMR Schlagnitweit, J.; Sandoz, S. F.; Jaworski, A.; Guzzetti, I.; Aussenac, F.; Carbajo, R. J.; Chiarparin, E.; Pell, A. J.; Petzold, K. 10.1101/589812 — biophysics — Posted on 2019-03-27 532 Cell signalling stabilizes morphogenesis against noise Hagolani, P.; Zimm, R.; Marin-Riera, M.; Salazar-Ciudad, I. 10.1101/590794 — developmental biology — Posted on 2019-03-27 533 Detection and characterization of apoptotic and necrotic cell death by time-lapse quantitative phase image analysis Vicar, T.; Raudenska, M.; Gumulec, J.; Masarik, M.; Balvan, J. 10.1101/589697 — cell biology — Posted on 2019-03-27 534 Identification of a human adult cardiac stem cell population with neural crest origin Höving, A. L.; Merten, M.; Schmidt, K. E.; Faust, I.; Ruiz-Perera, L. M.; Hachmeister, H.; Sommer, S.-P.; Fujita, B.; Pühler, T.; Huser, T.; Greiner, J. F. W.; Kaltschmidt, B.; Gummert, J.; Knabbe, C.; Kaltschmidt, C. 10.1101/590679 — cell biology — Posted on 2019-03-27 535 Volumetric two-photon imaging in live cells and embryos via axially gradient excitation Gao, Y.; Xia, X.; Yu, J.; Chen, T.; Xu, Z.; Xiao, L.; Wang, L.; Yan, F.; Du, Z.; Chu, J.; Zheng, H.; Li, H.; Zheng, W. 10.1101/589317 — bioengineering — Posted on 2019-03-27 536 Using the past to estimate sensory uncertainty Beierholm, U.; Rohe, T.; Ferrari, A.; Stegle, O.; Noppeney, U. 10.1101/589275 — neuroscience — Posted on 2019-03-27 537 Speciation with gene flow across an elevational gradient in New Guinea kingfishers Linck, E.; Freeman, B. G.; Dumbacher, J. P. 10.1101/589044 — evolutionary biology — Posted on 2019-03-27 538 A chemical counterpunch: Chromobacterium violaceum ATCC31532 produces violacein in response to translation-inhibiting antibiotics Lozano, G. L.; Guan, C.; Cao, Y.; Borlee, B. R.; Broderick, N. A.; Stabb, E. V.; Handelsman, J. 10.1101/589192 — microbiology — Posted on 2019-03-27 539 Consequences of consumer origin and omnivory on stability in experimental food web modules Granados, M.; Pagnucco, K. S.; Ricciardi, A. 10.1101/589259 — ecology — Posted on 2019-03-27 540 VRmol: an Integrative Cloud-Based Virtual Reality System to Explore Macromolecular Structure Xu, K.; Liu, N.; Xu, J.; Guo, C.; Zhao, L.; Wang, H.-w.; Zhang, Q. C. 10.1101/589366 — bioinformatics — Posted on 2019-03-27 541 Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study Pillinger, T.; Osimo, E.; de Marvao, A.; Berry, A.; Whitehurst, T.; Statton, B.; Quinlan, M.; Brugger, S.; Vazir, A.; Cook, S.; O'Regan, D.; Howes, O. 10.1101/589093 — physiology — Posted on 2019-03-27 542 Ray tracing 3D spectral scenes through human optics models Lian, T.; MacKenzie, K. J.; Brainard, D. H.; Cottaris, N. P.; Wandell, B. A. 10.1101/589234 — neuroscience — Posted on 2019-03-27 543 Direct and transgenerational effects of an experimental heat wave on early life stages in a freshwater snail Leicht, K.; Seppala, O. 10.1101/449777 — ecology — Posted on 2019-03-27 544 Dual RNA-Seq meta-analysis in Plasmodium infection Mukherjee, P.; Heitlinger, E. 10.1101/576116 — bioinformatics — Posted on 2019-03-27 545 No evidence that portion size influences food consumption in male Sprague Dawley rats Naneix, F.; Pinder, S. C.; Summers, M. Y.; Rouleau, R. M.; Robinson, E.; Myers, K. P.; McCutcheon, J. E. 10.1101/524272 — animal behavior and cognition — Posted on 2019-03-27 546 False-positive neuroimaging: Undisclosed flexibility in testing spatial hypotheses allows presenting anything as a replicated finding Hong, Y.; Yoo, Y.; Han, J.; Wager, T.; Woo, C.-W. 10.1101/514521 — neuroscience — Posted on 2019-03-27 547 Target of selective auditory attention can be robustly followed with MEG Kurmanaviciute, D.; Rantala, A.; Jas, M.; Valila, A.; Parkkonen, L. 10.1101/588491 — neuroscience — Posted on 2019-03-27 548 Clinical, imaging genetics and deformation based morphometry study of longitudinal changes after surgery for intractable aggressive behaviour Venetucci Gouveia, F.; Germann, J.; Campelo Borba de Morais, R. M.; Talamoni Fonoff, E.; Hamani, C.; Alho, E. J.; Brentani, H.; Martins, A. P.; Devenyi, G. A.; Patel, R.; Steele, C. J.; Gramer, R.; Chakravarty, M. M.; Chacon Ruiz Martinez, R. 10.1101/548826 — clinical trials — Posted on 2019-03-27 549 Detailed analysis of paternal knockout Grb10 mice suggests effects on stability of social behavior, rather than social dominance Rienecker, K.; Chavasse, A.; Moorwood, K.; Ward, A.; Isles, A. 10.1101/493692 — animal behavior and cognition — Posted on 2019-03-27 550 Human Foveal Cone Photoreceptor Topography and its Dependence on Eye Length Wang, Y.; Bensaid, N.; Tiruveedhula, P.; Ma, J.; Ravikumar, S.; Roorda, A. 10.1101/589135 — neuroscience — Posted on 2019-03-27 551 Cortical changes associated with parenthood are present in late life Orchard, E. R.; Ward, P. G. D.; Sforazzini, F.; Storey, E.; Egan, G. F.; Jamadar, S. D. 10.1101/589283 — neuroscience — Posted on 2019-03-27 552 Host porphobilinogen deaminase deficiency confers malaria resistance in Plasmodium chabaudi but not in Plasmodium falciparum or Plasmodium berghei during intraerythrocytic growth Schnider, C. B.; Yang, H.; Starrs, L.; Ehmann, A.; Rahimi, F.; Di Pierro, E.; Graziadei, G.; Matthews, K.; de Koning-Ward, T.; Bauer, D. C.; Foote, S.; McMorran, B.; Burgio, G. 10.1101/589242 — microbiology — Posted on 2019-03-27 553 Transcriptomic analysis of insecticide resistance in the lymphatic filariasis vector Culex quinquefasciatus Silva Martins, W. F.; Wilding, C. S.; Isaacs, A. T.; Rippon, E. J.; Megy, K.; Donnelly, M. J. 10.1101/589028 — genomics — Posted on 2019-03-27 554 Effect of READ1 on latent profiles of reading disability and comorbid attention and language learning disability subtypes Li, M.; Truong, D.; DeMille, M.; Malins, J.; Lovett, M.; Bosson-Heenan, J.; Gruen, J. R.; Frijters, J. 10.1101/589226 — genetics — Posted on 2019-03-27 555 A test of the evolution of increased competitive ability in two invaded regions Rotter, M.; Vallejo-Marin, M.; Holeski, L. M. 10.1101/589143 — ecology — Posted on 2019-03-27 556 Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells Sachdev, S.; Boyd, R.; Grimsey, N. L.; Connor, M. 10.1101/589341 — pharmacology and toxicology — Posted on 2019-03-27 557 From acoustic to linguistic analysis of temporal speech structure: acousto-linguistic transformation during speech perception using speech quilts. Overath, T.; Paik, J. H. 10.1101/589010 — neuroscience — Posted on 2019-03-27 558 Comparative genomic analysis of three salmonid species identifies functional candidate genes involved in resistance to the intracellular bacteria Piscirickettsia salmonis Yanez, J. M.; Yoshida, G. M.; Parra, A.; Correa, K.; Barria, A.; Bassini, L. N.; Christensen, K. A.; Lopez, M. E.; Carvalheiro, R.; Lhorente, J. P.; Pulgar, R. 10.1101/589200 — genomics — Posted on 2019-03-27 559 Trans-membrane association of the Sec and BAM complexes for bacterial outer-membrane biogenesis Alvira-de-Celis, S.; Watkins, D. W.; Troman, L.; Lorriman, J.; Daum, B.; Gold, V. A. M.; Collinson, I. 10.1101/589077 — biochemistry — Posted on 2019-03-27 560 Knowledge of Chagas disease in Latin American migrant population living in Japan and factors associated with knowledge level Iglesias-Rodriguez, I. M.; Mizukami, S.; Manh, D. H.; Thuan, T. M.; Justiniano, H. A.; Miura, S.; Ito, G.; Huy, N. T.; Hirayama, K. 10.1101/589051 — scientific communication and education — Posted on 2019-03-27 561 The haploinsufficient tumor suppressor Tip60 negatively regulates the oncogenic Aurora B kinase Bose, A.; Sudevan, S.; Rao, V. J.; Shima, H.; Igarashi, K.; Kundu, T. K. 10.1101/589473 — biochemistry — Posted on 2019-03-27 562 Genome-wide association study of Parkinsons disease progression biomarkers in 12 longitudinal patients cohorts Iwaki, H.; Blauwendraat, C.; Leonard, H. L.; Kim, J. J.; Liu, G.; Maple-Grodem, J.; Corvol, J.-C.; Pihlstrom, L.; van Nimwegen, M.; Hutten, S. J.; Khanh-Dung, H. N.; Rick, J.; Eberly, S.; Faghri, F.; Auinger, P.; Scott, K. M.; Wijeyekoon, R.; Van Deerlin, V. M.; Hernandez, D. G.; Gibbs, J. R.; Chitrala, K. N.; Day-Williams, A. G.; Brice, A.; Alves, G.; Noyce, A. J.; Tysnes, O.-B.; Evans, J. R.; Breen, D. P.; Estrada, K.; Wegel, C. E.; Danjou, F.; Simon, D. K.; Andreassen, O.; Ravina, B.; Toft, M.; Heutink, P.; Bloem, B. R.; Weintraub, D.; Barker, R. A.; Williams-Gray, C. H.; van de Warrenburg, 10.1101/585836 — genetics — Posted on 2019-03-27 563 Consciousness as a Concrete Physical Phenomenon Jylkka, J.; Railo, H. 10.1101/557561 — neuroscience — Posted on 2019-03-27 564 Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes Kumar, V.; Doharey, P. K.; Gulati, S.; Meehan, J.; Martinez, M. G.; Hughes, K.; Mooers, B. H. M.; Cruz-Reyes, J. 10.1101/524702 — molecular biology — Posted on 2019-03-27 565 Zika Virus Subverts Stress Granules to Promote and Restrict Viral Gene Expression Bonenfant, G.; Williams, N.; Netzband, R.; Schwarz, M.; Evans, M. J.; Pager, C. T. 10.1101/436865 — microbiology — Posted on 2019-03-27 566 Molecular evolution of non-fertilizing sperm in Lepidoptera suggests minimal direct involvement in sperm competition Mongue, A. J.; Hansen, M. E.; Gu, L.; Sorenson, C. E.; Walters, J. R. 10.1101/404236 — evolutionary biology — Posted on 2019-03-27 567 Emergence and suppression of cooperation by action visibility in transparent games Unakafov, A. M.; Schultze, T.; Kagan, I.; Gail, A.; Moeller, S.; Eule, S.; Wolf, F. 10.1101/314500 — evolutionary biology — Posted on 2019-03-27 568 hicap: in silico serotyping of the Haemophilus influenzae capsule locus Watts, S. C.; Holt, K. E. 10.1101/543454 — bioinformatics — Posted on 2019-03-27 569 Strengths and potential pitfalls of hay-transfer for ecological restoration revealed by RAD-seq analysis in floodplain Arabis species Dittberner, H.; Becker, C.; Jiao, W.-B.; Schneeberger, K.; Hoelzel, N.; Tellier, A.; de Meaux, J. 10.1101/474858 — ecology — Posted on 2019-03-27 570 The degree of polymerization and sulfation patterns in heparan sulfate are critical determinants of cytomegalovirus infectivity Hasan, M.; Parmar, R.; Liang, Q.; Qiu, H.; Tiwari, V.; Sharp, J.; Wang, L.; Tandon, R. 10.1101/590463 — microbiology — Posted on 2019-03-26 571 Transcriptome-based prediction of complex traits in maize Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H. 10.1101/587121 — genetics — Posted on 2019-03-26 572 Modeling the growth of organisms validates a general relation between metabolic costs and natural selection Ilker, E.; Hinczewski, M. 10.1101/358440 — evolutionary biology — Posted on 2019-03-26 573 Correlating Synaptic Ultrastructure and Function at the Nanoscale Maus, L.; Altas, B.; Rhee, J.; Brose, N.; Imig, C.; Cooper, B. H. 10.1101/588848 — neuroscience — Posted on 2019-03-26 574 Shared and distinct genetic risk factors for childhood onset and adult onset asthma: genome- and transcriptome-wide Studies Pividori, M.; Schoettler, N.; Nicolae, D. L.; Ober, C.; Im, H. K. 10.1101/427427 — genetics — Posted on 2019-03-26 575 Impact of initial protein stability on local fitness landscapes Faber, M. S.; Wrenbeck, E. E.; Azouz, L. R.; Steiner, P. J.; Whitehead, T. A. 10.1101/590398 — evolutionary biology — Posted on 2019-03-26 576 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity Hong, Y.; Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G. 10.1101/588624 — cell biology — Posted on 2019-03-26 577 Electroporation characteristics of human primary T cells Aksoy, P.; Aksoy, B. A.; Czech, E.; Hammerbacher, J. 10.1101/466243 — immunology — Posted on 2019-03-26 578 Development and Application of a Tri-allelic PCR Assay for Screening Vgsc-L1014F Kdr Mutations Associated with Pyrethroid and Organochlorine Resistance in the Mosquito Culex quinquefasciatus Silva Martins, W. F.; Silva Pereira, B. N.; Vieira Alves, A. T.; Murphy, A.; Silva Martins, P. G.; Weetman, D.; Wilding, C. S.; Donnelly, M. J. 10.1101/588905 — genetics — Posted on 2019-03-26 579 Familiar neighbors, but not relatives, enhance fitness in a territorial mammal Siracusa, E.; Boutin, S.; Dantzer, B.; Lane, J. E.; Coltman, D. W.; McAdam, A. G. 10.1101/589002 — evolutionary biology — Posted on 2019-03-26 580 tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing Krause, M.; Niazi, A. M.; Labun, K.; Müller, F. S.; Torres Cleuren, Y. N.; Valen, E. 10.1101/588343 — bioinformatics — Posted on 2019-03-26 581 Caspase-mediated cleavage of murine norovirus NS1/2 potentiates apoptosis and is required for persistent infection of intestinal epithelial cells Robinson, B. A.; Van Winkle, J. A.; McCune, B. T.; Peters, A. M.; Nice, T. J. 10.1101/372615 — microbiology — Posted on 2019-03-26 582 Application of Volumetric Absorptive Micro Sampling to Measure Multidimensional Anti-Influenza Hemagglutinin IgG Antibodies by mPlex-Flu Assay Wang, J.; Li, D.; Wiltse, A.; Emo, J.; Hilchey, S. P.; Zand, M. S. 10.1101/588038 — immunology — Posted on 2019-03-26 583 Development of a drug repressible β-catenin mutant mouse to examine effect of activated β-catenin signaling on long-term maintenance of mammary tumor growth Gorman, J. L.; Adams, J. R.; Jones, E. M.; Egan, S. E.; Woodgett, J. R. 10.1101/588459 — cancer biology — Posted on 2019-03-26 584 Denoising of Aligned Genomic Data Fischer-Hwang, I.; Ochoa, I.; Weissman, T.; Hernaez, M. 10.1101/590372 — bioinformatics — Posted on 2019-03-26 585 Estimation of mutual information for real-valued data with error bars and controlled bias Holmes, C. M.; Nemenman, I. 10.1101/589929 — bioinformatics — Posted on 2019-03-26 586 Quantitatively predicting optimal antibiotic dose levels from drug-target binding Clarelli, F.; Palmer, A.; Singh, B.; Storflor, M.; Lauksund, S.; Cohen, T.; Abel, S.; Abel zur Wiesch, P. 10.1101/369975 — biochemistry — Posted on 2019-03-26 587 Hippocampal-midbrain circuit enhances the pleasure of anticipation in the prefrontal cortex Iigaya, K.; Hauser, T. U.; Kurth-Nelson, Z.; O'Doherty, J. P.; Dayan, P.; Dolan, R. J. 10.1101/588699 — neuroscience — Posted on 2019-03-26 588 Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation Selewa, A.; Dohn, R.; Eckart, H.; Lozano, S.; Xie, B.; Gauchat, E.; Elorbany, R.; Rhodes, K.; Burnett, J.; Gilad, Y.; Pott, S.; Basu, A. 10.1101/585901 — genomics — Posted on 2019-03-26 589 A logical model of homology for comparative biology Mabee, P.; Balhoff, J.; Dahdul, W.; Lapp, H.; Mungall, C.; Vision, T. 10.1101/588822 — evolutionary biology — Posted on 2019-03-26 590 Dual RNA-Seq meta-analysis in Plasmodium infection Mukherjee, P.; Heitlinger, E. 10.1101/576116 — bioinformatics — Posted on 2019-03-26 591 Easily adaptable head-free training system of macaques for tasks requiring precise measurements of eye position Kawaguchi, K.; Pourriahi, P.; Seillier, L.; Clery, S.; Nienborg, H. 10.1101/588566 — neuroscience — Posted on 2019-03-26 592 Reward revaluation biases hippocampal replay content away from the preferred outcome Carey, A. A.; Tanaka, Y.; van der Meer, M. 10.1101/397950 — neuroscience — Posted on 2019-03-26 593 Unique Trophoblast Chromatin Environment Mediated by the PcG Protein SFMBT2 Tang, P.; Miri, K.; Varmuza, S. 10.1101/590356 — genomics — Posted on 2019-03-26 594 The convergent evolution of eusociality is based on a shared reproductive groundplan plus lineage-specific sets of plastic genes Warner, M. R.; Qiu, L.; Holmes, M. J.; Mikheyev, A. S.; Linksvayer, T. A. 10.1101/454645 — evolutionary biology — Posted on 2019-03-26 595 Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes Lee, D.; Zdraljevic, S.; Cook, D. E.; Frezal, L.; Hsu, J.-C.; Sterken, M. G.; Riksen, J. A. G.; Wang, J.; Kammenga, J. E.; Braendle, C.; Felix, M.-A.; Schroeder, F. C.; Andersen, E. C. 10.1101/580803 — evolutionary biology — Posted on 2019-03-26 596 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs Marchant, A.; Cisneros, A.; Dube, A. K.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C. R. 10.1101/564401 — evolutionary biology — Posted on 2019-03-26 597 Tetraploidy in rodent cardiac stem cells confers enhanced biological properties Broughton, K.; Khieu, T.; Nguyen, N.; Rosa, M.; Mohsin, S.; Quijada, P.; Wang, J.; Echeagaray, O.; Kubli, D.; Kim, T.; Firouzi, F.; Monsanto, M.; Gude, N.; Adamson, R.; Dembitsky, W.; Davis, M.; Sussman, M. 10.1101/521716 — cell biology — Posted on 2019-03-26 598 Automatic structure-based NMR methyl resonance assignment in large proteins Pritisanac, I.; Würz, J. M.; Alderson, T. R.; Güntert, P. 10.1101/538272 — biophysics — Posted on 2019-03-26 599 scAlign: a tool for alignment, integration and rare cell identification from scRNA-seq data Johansen, N.; Quon, G. 10.1101/504944 — bioinformatics — Posted on 2019-03-26 600 ntEdit: scalable genome sequence polishing Warren, R. L.; Coombe, L.; Mohamadi, H.; Zhang, J.; Jaquish, B.; Isabel, N.; Jones, S. J.; Bousquet, J.; Bohlmann, J.; Birol, I. 10.1101/565374 — bioinformatics — Posted on 2019-03-26 601 Action enhances perception: Visually evoked neural responses are enhanced when engaging in a motor task Ki, J. J.; Parra, L. C.; Dmochowski, J. 10.1101/588806 — neuroscience — Posted on 2019-03-26 602 Structure of a Tc holotoxin pore provides insights into the translocation mechanism Roderer, D.; Hofnagel, O.; Benz, R.; Raunser, S. 10.1101/590430 — molecular biology — Posted on 2019-03-26 603 Moving microbes: the dynamics of transient microbial residence on human skin Vandegrift, R.; Fahimipour, A. K.; Muscarella, M.; Bateman, A. C.; Van Den Wymelenberg, K.; Bohannan, B. 10.1101/586008 — microbiology — Posted on 2019-03-26 604 CD16-158-VALINE CHIMERIC RECEPTOR T CELLS OVERCOME THE RESISTANCE OF KRAS-MUTATED COLORECTAL CARCINOMA CELLS TO CETUXIMAB Arriga, R.; Caratelli, S.; Lanzilli, G.; Ottaviani, A.; Cenciarelli, C.; Sconocchia, T.; Spagnoli, G. C.; Iezzi, G.; Roselli, M.; Lauro, D.; Dotti, G.; Ferrone, S.; Sconocchia, G. 10.1101/588525 — immunology — Posted on 2019-03-26 605 Splicing conservation signals in plant long non-coding RNAs Corona-Gomez, J. A.; Garcia-Lopez, I. J.; Stadler, P. F.; Fernandez-Valverde, S. L. 10.1101/588954 — genomics — Posted on 2019-03-26 606 Food Webs: Insights from a General Ecosystem Model Flores, C.; Kortsch, S.; Tittensor, D. P.; Harfoot, M.; Purves, D. 10.1101/588665 — ecology — Posted on 2019-03-26 607 NatB modulates Rb mutant cell death and tumor growth by regulating EGFR/MAPK signaling through the N-end rule pathways Sheng, Z.; Du, W. 10.1101/590349 — cell biology — Posted on 2019-03-26 608 Model-based tumor subclonal reconstruction Caravagna, G.; Heide, T.; Williams, M.; Zapata, L.; Nichol, D.; Chkhaidze, K.; Cross, W. H.; Cresswell, G. D.; Werner, B.; Acar, A.; Barnes, C. P.; Sanguinetti, G.; Graham, T. A.; Sottoriva, A. 10.1101/586560 — bioinformatics — Posted on 2019-03-26 609 Depletion of resident muscle stem cells inhibits muscle fiber hypertrophy induced by lifelong physical activity Englund, D.; Murach, K.; Dungan, C.; Figueiredo, V.; Vechetti, I.; Dupont-Versteegden, E.; McCarthy, J.; Peterson, C. 10.1101/588731 — physiology — Posted on 2019-03-26 610 Functional relevance of dual olfactory bulb in olfactory coding Kuruppath, P.; Belluscio, L. 10.1101/588996 — neuroscience — Posted on 2019-03-26 611 Characteristic sounds facilitate object search in real-life scenes Kvasova, D.; Garcia-Vernet, L.; Soto-Faraco, S. 10.1101/563080 — neuroscience — Posted on 2019-03-26 612 Time-resolved NMR monitoring of tRNA maturation Barraud, P.; Gato, A.; Heiss, M.; Catala, M.; Kellner, S.; Tisne, C. 10.1101/588814 — molecular biology — Posted on 2019-03-26 613 A Membrane-Bound Cytochrome Enables Methanosarcina acetivorans to Conserve Energy to Support Growth from Extracellular Electron Transfer Holmes, D.; Ueki, T.; Tang, H.-Y.; Zhou, J.; Smith, J.; Chaput, G.; Lovley, D. 10.1101/590380 — microbiology — Posted on 2019-03-26 614 Evolutionary dynamics and diversification in changing environments Alekseeva, E.; Ispolatov, I.; Doebeli, M. 10.1101/590406 — biophysics — Posted on 2019-03-26 615 DEEPCON: Protein Contact Prediction using Dilated Convolutional Neural Networks with Dropout Adhikari, B. 10.1101/590455 — bioinformatics — Posted on 2019-03-26 616 Metabolic cost calculations of gait using musculoskeletal energy models, a comparison study Koelewijn, A. D.; Heinrich, D.; van den Bogert, A. J. 10.1101/588590 — physiology — Posted on 2019-03-26 617 Mechanisms of Economic Decisions under Sequential Offers Ballesta, S.; Padoa-Schioppa, C. 10.1101/590422 — neuroscience — Posted on 2019-03-26 618 Bioremediation of soils contaminated with petroleum solid wastes and drill cuttings by Pleurotus sp. strains under different treatment scales Romero-Silva, R.; Sanchez Reyes, A.; Diaz-Rodriguez, Y.; Batista-Garcia, R. A.; Hernandez-Hernandez, D.; Tabullo de Robles, J. 10.1101/588673 — microbiology — Posted on 2019-03-26 619 Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity Mikhaylova, A. G.; Mikhailova, A. A.; Ushakova, K.; Tretyakov, E.; Iurchenko, A.; Zazhytska, M.; Knorre, D.; Zdobnov, E.; Fleischmann, Z.; Annis, S.; Franco, M.; Wasko, K.; Kunz, W.; Mazunin, I.; Nikolaev, S.; Reymond, A.; Khrapko, K.; Gunbin, K.; Popadin, K. 10.1101/589168 — genomics — Posted on 2019-03-26 620 A Signature of Passivity? An Explorative Study of the N3 Event-Related Potential Component in Passive Oddball Tasks Kotchoubey, B.; Pavlov, Y. G. 10.1101/271502 — neuroscience — Posted on 2019-03-26 621 Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs Ibn-Salem, J.; Andrade-Navarro, M. A. 10.1101/257584 — genomics — Posted on 2019-03-26 622 Do Arabidopsis Squamosa promoter binding Protein-Like genes act together in plant acclimation to copper or zinc deficiency? Schulten, A.; Bytomski, L.; Quintana, J.; Bernal, M.; Kraemer, U. 10.1101/590182 — plant biology — Posted on 2019-03-26 623 The C-terminal domains SnRK2-box and ABA-box have a role in sugarcane SnRK2s auto-activation and activity Righetto, G. L.; Sriranganadane, D.; Halabelian, L.; Gottschald Chiodi, C.; Elkins, J.; Massirer, K. B.; Gileadi, O.; Menossi, M.; Counago, R. 10.1101/589903 — plant biology — Posted on 2019-03-26 624 Practiced naming of objects and actions: An fMRI study Delikishkina, E.; Lingnau, A.; Miceli, G. 10.1101/590026 — neuroscience — Posted on 2019-03-26 625 Simultaneous tracking of division and differentiation from individual hematopoietic stem and progenitor cells reveals within-family homogeneity despite population heterogeneity Tak, T.; Prevedelllo, G.; Simon, G.; Paillon, N.; Duffy, K. R.; Perie, L. 10.1101/586354 — immunology — Posted on 2019-03-26 626 Irgm1-deficiency leads to myeloid dysfunction in colon lamina propria and susceptibility to the intestinal pathogen Citrobacter rodentium Taylor, G.; Huang, H.-I.; Fee, B. E.; Youssef, N.; Cantillana, V.; Schoenborn, A.; Rogala, A. R.; Buckley, A. F.; Vallance, B. A.; Gulati, A. S.; Hammer, G. E. 10.1101/575415 — immunology — Posted on 2019-03-26 627 Scientific evaluation of negative exome sequencing followed by systematic scoring of candidate genes to decipher the genetics of neurodevelopmental disorders Buttner, B.; Martin, S.; Finck, A.; Arelin, M.; Baade-Buttner, C.; Bartolomaeus, T.; Bauer, P.; Bertsche, A.; Bernhard, M. K.; Biskup, S.; Di Donato, N.; Elgizouli, M.; Ewald, R.; Heine, C.; Hellenbroich, Y.; Hentschel, J.; Hoffjan, S.; Horn, S.; Hornemann, F.; Huhle, D.; Kamphausen, S. B.; Kiess, W.; Krey, I.; Kuechler, A.; Liesfeld, B.; Merkenschlager, A.; Mitter, D.; Muschke, P.; Pfaffle, R.; Polster, T.; Schanze, I.; Schlump, J.-U.; Syrbe, S.; Wieczorek, D.; Zenker, M.; Lemke, J. R.; Le Duc, D.; Platzer, K.; Abou Jamra, R. 10.1101/588517 — genetics — Posted on 2019-03-26 628 The dot-compartment revealed? Diffusion MRI with ultra-strong gradients and spherical tensor encoding in the living human brain Tax, C. M. W.; Szczepankiewicz, F.; Nilsson, M.; Jones, D. K. 10.1101/584730 — neuroscience — Posted on 2019-03-26 629 The PIWI/piRNA response is relaxed in a rodent that lacks mobilizing transposable elements Vandewege, M. W.; Platt, R. N.; Merriman, D. K.; Ray, D. A.; Hoffmann, F. G. 10.1101/587030 — evolutionary biology — Posted on 2019-03-26 630 PamgeneAnalyzeR open and reproducible pipeline for kinase profiling Bekkar, A.; Nasrallah, A.; Guex, N.; Fajas, L.; Xenarios, I.; Lopez-Mejia, I. C. 10.1101/589838 — bioinformatics — Posted on 2019-03-26 631 Integrative analysis of epigenetics data identifies gene-specific regulatory elements Schmidt, F.; Marx, A.; Hebel, M.; Wegner, M.; Baumgarten, N.; Kaulich, M.; Goeke, J.; Vreeken, J.; Schulz, M. H. H. 10.1101/585125 — bioinformatics — Posted on 2019-03-26 632 Target of selective auditory attention can be robustly followed with MEG Kurmanaviciute, D.; Rantala, A.; Jas, M.; Valila, A.; Parkkonen, L. 10.1101/588491 — neuroscience — Posted on 2019-03-26 633 Near-optimal combination of disparity across a log-polar scaled visual field Maiello, G.; Chessa, M.; Bex, P. J.; Solari, F. 10.1101/589937 — neuroscience — Posted on 2019-03-26 634 Xrn1 activity broadly represses RNA polymerase II occupancy at mammalian but not viral promoters during herpesvirus infection Hartenian, E.; Glaunsinger, B. 10.1101/585984 — microbiology — Posted on 2019-03-26 635 The TCR/peptide/MHC complex with a superagonist peptide shows similar interface and reduced flexibility compared to the complex with a self-peptide Salutari, I.; Martin, R.; Caflisch, A. 10.1101/588483 — immunology — Posted on 2019-03-26 636 Distribution of iridescent colours in hummingbird communities results from the interplay between selection for camouflage and communication Gruson, H.; Elias, M.; Parra, J. L.; Andraud, C.; Berthier, S.; Doutrelant, C.; Gomez, D. 10.1101/586362 — ecology — Posted on 2019-03-26 637 Graph analysis of looming-selective networks in the tectum, and its replication in a simple computational model Khakhalin, A. 10.1101/589887 — neuroscience — Posted on 2019-03-26 638 Balanced activity of multiple FtsW and RodA proteins is crucial for maintaining cell shape and antibiotic resistance in Listeria monocytogenes Rismondo, J.; Halbedel, S.; Grundling, A. 10.1101/589911 — microbiology — Posted on 2019-03-26 639 Hybrid decay: a transgenerational epigenetic decline in vigor and viability triggered in backcross populations of teosinte with maize Xue, W.; Anderson, S. N.; Wang, X.; Yang, L.; Crisp, P. A.; Li, Q.; Noshay, J.; Albert, P. S.; Birchler, J. A.; Bilinski, P.; Stitzer, M.; Ross-Ibarra, J.; Flint-Garcia, S.; Chen, X.; Springer, N. M.; Doebley, J. F. 10.1101/588715 — genetics — Posted on 2019-03-26 640 Stoichiometric constraints modulate the effects of temperature and nutrients on biomass distribution and community stability Sentis, A.; Haegeman, B.; Montoya, J. M. 10.1101/589895 — ecology — Posted on 2019-03-26 641 Estimation of mutual information for real-valued data with error bars and controlled bias Holmes, C. M.; Nemenman, I. 10.1101/589929 — bioinformatics — Posted on 2019-03-26 642 Two forms of phosphomannomutase in gammaproteobacteria: The overlooked membrane-bound form of AlgC is required for twitching motility of Lysobacter enzymogenes Qian, G.; Fei, S.; Galperin, M. Y. 10.1101/589796 — microbiology — Posted on 2019-03-26 643 Combinatorial genetic analysis of a regulatory network reveals the importance of higher order epistasis for gene deletion phenotypes new, a.; Lehner, B. 10.1101/589606 — genetics — Posted on 2019-03-26 644 Mutualistic interactions with phoretic mites Poecilochirus carabi expand the realised thermal niche of the burying beetle Nicrophorus vespilloides Sun, S.-J.; Kilner, R. M. 10.1101/590125 — ecology — Posted on 2019-03-26 645 The FH2 domain of formin proteins is critical for platelet cytoskeletal dynamics Green, H. L. H.; Zuidscherwoude, M.; Thomas, S. G. 10.1101/589861 — cell biology — Posted on 2019-03-26 646 Breast cancer classification based on proteotypes obtained by SWATH mass spectrometry Bouchal, P.; Schubert, O. T.; Faktor, J.; Capkova, L.; Imrichova, H.; Zoufalova, K.; Paralova, V.; Hrstka, R.; Liu, Y.; Ebhardt, H. A.; Budinska, E.; Nenutil, R.; Aebersold, R. 10.1101/583443 — cancer biology — Posted on 2019-03-26 647 ntEdit: scalable genome sequence polishing Warren, R. L.; Coombe, L.; Mohamadi, H.; Zhang, J.; Jaquish, B.; Isabel, N.; Jones, S. J.; Bousquet, J.; Bohlmann, J.; Birol, I. 10.1101/565374 — bioinformatics — Posted on 2019-03-26 648 Low-background Acyl-biotinyl Exchange Largely Eliminates the Co-isolation of Non-S-acylated Proteins and Enables Deep S-acylproteomic Analysis Zhou, B.; Wang, Y.; Yan, Y.; Mariscal, J.; Di Vizio, D.; Freeman, M. R.; Yang, W. 10.1101/588988 — biochemistry — Posted on 2019-03-26 649 Crab fisherman communities in north Brazil: a new high risk population for vampire bat rabies de Paula Silva, N.; Andrade, E. A.; Cardoso, D.; de Souza Guimaraes, R.; Silva, M. B.; Gomes Nascimento, K. K.; de Arruda Xavier, D.; Abel Bezerra, I. 10.1101/590083 — epidemiology — Posted on 2019-03-26 650 Levels of histidine-rich glycoprotein variants in human blood are associated to chronological age and predict mortality Hong, M.-G.; Dodig-Crnkovic, T.; Chen, X.; Drobin, K.; LEE, W.; Wang, Y.; Sjöberg, R.; Odeberg, J.; Hamsten, A.; Silveira, A.; Hall, P.; Nilsson, P.; Pawitan, Y.; Hägg, S.; Uhlen, M.; Pedersen, N. L.; Magnusson, P. K. E.; Schwenk, J. M. 10.1101/464909 — epidemiology — Posted on 2019-03-26 651 Poor seed quality, reduced germination, and decreased seedling vigor in soybean is linked to exposure of the maternal lines to drought stress wijewardana, C.; Reddy, K. R.; Krutz, L.; Gao, W.; Bellaloui, N. 10.1101/590059 — plant biology — Posted on 2019-03-26 652 A Simple way to Improve a Conventional A/O-MBR for High Simultaneous Carbon and Nutrients Removal from Synthetic Municipal Wastewater Adoonsook, D.; Chia-Yuan, C.; Wongrueng, A.; Pumas, C. 10.1101/590042 — microbiology — Posted on 2019-03-26 653 Computational prediction and analysis of very high risk single nucleotide polymorphisms in human cytochrome P450 oxidoreductase gene Dhas, B. B.; K, R.; S, S.; Pavuluri, P.; K, Y. R. 10.1101/590067 — genomics — Posted on 2019-03-26 654 Genetic Mapping Of Morpho-Physiological Traits Involved During Reproductive Stage Drought Tolerance In Rice Barik, S. R.; Pandit, E.; Mohanty, S. P.; pradhan, s. K.; Mohapatra, T. 10.1101/590075 — genetics — Posted on 2019-03-26 655 Infection of Plasmodiophora brassicae changes the fungal endophyte community of tumourous stem mustard roots as revealed by high-throughput sequencing and culture-dependent methods Tian, X.; Wang, D.; Mao, Z.; Pan, L.; Liao, J.; Cai, Z. 10.1101/590018 — microbiology — Posted on 2019-03-26 656 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies Avila, P.; Fromhage, L.; Lehmann, L. 10.1101/454512 — evolutionary biology — Posted on 2019-03-26 657 Biophysical modeling of VIM to assess contributions of oscillatory activity to essential tremor Lee, S.; Segar, D. J.; Asaad, W.; Jones, S. 10.1101/339846 — neuroscience — Posted on 2019-03-26 658 Efficient and specific oligo-based depletion of rRNA Kraus, A. J.; Brink, B. G.; Siegel, T. N. 10.1101/589622 — molecular biology — Posted on 2019-03-26 659 Ethanolamine regulates CqsR quorum-sensing signaling in Vibrio cholerae Ng, W.-L.; Watve, S.; Barrasso, K.; Jung, S. A.; Davis, K. J.; Hawver, L. A.; Khataokar, A.; Palaganas, R. G.; Neiditch, M. B.; Perez, L. J. 10.1101/589390 — microbiology — Posted on 2019-03-26 660 A major role for Eco1 in regulating cohesin-mediated mitotic chromosome folding Dauban, L.; Montagne, R.; Thierry, A.; Lazar-Stefanita, L.; Gadal, O.; Cournac, A.; Koszul, R.; Beckouet, F. 10.1101/589101 — genetics — Posted on 2019-03-26 661 Gene-level quantitative trait mapping in an expanded C. elegans multiparent experimental evolution panel Noble, L. M.; Rockman, M. V.; Teotonio, H. 10.1101/589432 — evolutionary biology — Posted on 2019-03-26 662 Drosophila ovarian germline stem cell cytocensor projections dynamically receive and attenuate BMP signalling Wilcockson, S. G.; Ashe, H. L. 10.1101/370486 — developmental biology — Posted on 2019-03-26 663 An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21 McRae, E. K. S.; Dupas, S. J.; Booy, E. P.; Piragasam, R. S.; Fahlman, R. P.; McKenna, S. A. 10.1101/588798 — biochemistry — Posted on 2019-03-26 664 Genome-wide analysis of MIKC-type MADS-box genes in wheat: pervasive duplications may have facilitated adaptation to different environmental conditions Schilling, S.; Kennedy, A.; Pan, S.; Jermiin, L. S.; Melzer, R. 10.1101/585232 — plant biology — Posted on 2019-03-26 665 Evaluating Muscle Fiber Contractility and the Transcriptome, Proteome, Metabolome, and Lipidome of the mdx/mTR Mouse Model of Duchenne Muscular Dystrophy Van Pelt, D. W.; Kharaz, Y. A.; Sarver, D. C.; Eckhardt, L. R.; Dzierzawski, J. T.; Disser, N. P.; Piacentini, A. N.; Comerford, E.; McDonagh, B.; Mendias, C. L. 10.1101/589424 — physiology — Posted on 2019-03-26 666 HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists Strutzenberg, T. S.; Garcia-Ordonez, R.; Novick, S.; Park, H.; Chang, M. R.; Doebellin, C.; He, Y.; Patouret, R.; Kamenecka, T.; Griffin, P. R. 10.1101/588830 — biophysics — Posted on 2019-03-26 667 Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination Hoff, K.; Halpain, M.; Garbagnati, G.; Edwards, J.; Zhou, W. 10.1101/561092 — synthetic biology — Posted on 2019-03-26 668 Chloroplasts Require Glutathione Reductase to Balance Reactive Oxygen Species and Maintain Efficient Photosynthesis Müller-Schüssele, S. J.; Wang, R.; Gütle, D. D.; Romer, J.; Rodriguez-Franco, M.; Scholz, M.; Lüth, V. M.; Kopriva, S.; Dörmann, P.; Schwarzländer, M.; Reski, R.; Michael, H.; Meyer, A. J. 10.1101/588442 — plant biology — Posted on 2019-03-26 669 Phase separation of zonula occludens proteins drives formation of tight junctions Beutel, O.; Maraspini, R.; Pombo-Garcia, K.; Martin-Lemaitre, C.; Honigmann, A. 10.1101/589580 — cell biology — Posted on 2019-03-26 670 Epigenomic Landscape of Arabidopsis thaliana Metabolism Reveals Bivalent Chromatin on Specialized Metabolic Genes Zhao, K.; Rhee, S. Y. 10.1101/589036 — systems biology — Posted on 2019-03-26 671 Unified rational protein engineering with sequence-only deep representation learning Alley, E. C.; Khimulya, G.; Biswas, S.; AlQuraishi, M.; Church, G. M. 10.1101/589333 — synthetic biology — Posted on 2019-03-26 672 Cross-talk between m6A and m1A regulators, YTHDF2 and ALKBH3 fine-tunes mRNA expression Lao, N.; Barron, N. 10.1101/589747 — molecular biology — Posted on 2019-03-26 673 A Polybasic Domain in aPKC Mediates Par-6-Dependent Control of Plasma Membrane Targeting and Kinase Activity Hong, Y.; Dong, W.; Lu, J.; Zhang, X.; Wu, Y.; Lettieri, K.; Hammond, G. 10.1101/588624 — cell biology — Posted on 2019-03-26 674 Lipid Interactions of a Ciliary Membrane TRP Channel: Simulation and Structural Studies of Polycystin-2 (PC2) Wang, Q.; Hedger, G.; Aryal, P.; Grieben, M.; Nasrallah, C.; Baronina, A.; Pike, A.; Shi, J.; Carpenter, E. P.; Sansom, M. 10.1101/589515 — biophysics — Posted on 2019-03-26 675 Metabolic labeling of RNAs uncovers hidden features and dynamics of the Arabidopsis thaliana transcriptome Szabo, E. X.; Reichert, P.; Lehniger, M.-K.; Ohmer, M.; de Francisco Amorim, M.; Gowik, U.; Schmitz-Linneweber, C.; Laubinger, S. 10.1101/588780 — plant biology — Posted on 2019-03-26 676 Size- and stage-dependence in cause-specific mortality of migratory brown trout Nater, C. R.; Vindenes, Y.; Aass, P.; Cole, D.; Langangen, O.; Moe, J.; Rustadbakken, A.; Turek, D.; Vollestad, L. A.; Ergon, T. 10.1101/544742 — ecology — Posted on 2019-03-26 677 Shh induces symmetry breaking in the presomitic mesoderm by inducing tissue shear and orientated cell rearrangements Yin, J.; Saunders, T. E. 10.1101/589549 — developmental biology — Posted on 2019-03-26 678 Random birth order and bursty Notch ligand expression drive the stochastic AC/VU cell fate decision in C. elegans Gritti, N.; Kienle, S.; Kroll, J. R.; Kriselj, A.; Goos, Y.; van Zon, J. 10.1101/588418 — developmental biology — Posted on 2019-03-26 679 The Human Exonuclease-1 Interactome And Phosphorylation Sites Eid, W.; Hess, D.; Koenig, C.; Gentili, C.; Ferrari, S. 10.1101/588574 — cell biology — Posted on 2019-03-26 680 Aurora kinase A mediated phosphorylation of mPOU is critical for skeletal muscle differentiation Karthigeyan, D.; Bose, A.; Boopathi, R.; Rao, V. J.; Shima, H.; Bharathy, N.; Igarashi, K.; Taneja, R.; Kundu, T. K. 10.1101/589754 — cell biology — Posted on 2019-03-26 681 Development of behavioral modernity by hominins around 70,000 years ago was associated with simultaneous acquisition of a novel component of imagination, called prefrontal synthesis, and conversion of a preexisting rich-vocabulary non-recursive communication system to a fully recursive syntactic language Vyshedskiy, A. 10.1101/166520 — evolutionary biology — Posted on 2019-03-26 682 Hemimetabolous insects elucidate the origin of sexual development via alternative splicing Wexler, J.; Delaney, E.; Belles, X.; Schal, C.; Wada-Katsumata, A.; Amicucci, M.; Kopp, A. 10.1101/587964 — developmental biology — Posted on 2019-03-26 683 Both galactosaminogalactan and α-1,3-glucan contribute to aggregation of Aspergillusoryzae hyphae in liquid culture Miyazawa, K.; Yoshimi, A.; Sano, M.; Tabata, F.; Sugahara, A.; Kasahara, S.; Koizumi, A.; Yano, S.; Nakajima, T.; Abe, K. 10.1101/589408 — cell biology — Posted on 2019-03-26 684 Disharmony of the world’s island floras Koenig, C.; Weigelt, P.; Taylor, A.; Stein, A.; Dawson, W.; Essl, F.; Pergl, J.; Pysek, P.; van Kleunen, M.; Winter, M.; Chatelain, C.; Wieringa, J. J.; Krestov, P.; Kreft, H. 10.1101/523464 — ecology — Posted on 2019-03-26 685 DDX3 depletion selectively represses translation of structured mRNAs Calviello, L.; Venkataramanan, S.; Rogowski, K. J.; Wyler, E.; Tejura, M.; Thai, B.; Krol, J.; Filipowicz, W.; Landthaler, M.; Floor, S. N. 10.1101/589218 — molecular biology — Posted on 2019-03-26 686 Comparative ChIP-seq (Comp-ChIP-seq): a novel computational methodology for genome-wide analysis Blanco, E.; Di Croce, L.; Aranda, S. 10.1101/532622 — genomics — Posted on 2019-03-26 687 In vitro reconstitution of kinetochore-microtubule interface reveals a fundamental error correction mechanism Doodhi, H.; Kasciukovic, T.; Gierlinski, M.; Li, S.; Clayton, L.; Tanaka, T. U. 10.1101/455873 — cell biology — Posted on 2019-03-26 688 Direct genome editing of patient-derived xenografts using CRISPR-Cas9 enables rapid in vivo functional genomics Hulton, C. H.; Costa, E. A.; Shah, N. S.; Quintanal-Villalonga, A.; Heller, G.; de Stanchina, E.; Rudin, C. M.; Poirier, J. T. 10.1101/588921 — cancer biology — Posted on 2019-03-26 689 Data from an electronic health informatics pipeline to describe clearance dynamics of Hepatitis B surface antigen (HBsAg) and e-Antigen (HBeAg) in chronic HBV infection Downs, L. O.; Smith, D.; Lumley, S. F.; Patel, M.; McNaughton, A. L.; Mokaya, J.; Ansari, A.; Salih, H.; Varnai, K. A.; Freeman, O.; Cripps, S.; Phillips, J.; Collier, J.; Woods, K.; Channon, K.; Davies, J.; Barnes, E.; Jeffery, K.; Matthews, P. C. 10.1101/494500 — microbiology — Posted on 2019-03-26 690 VHL Synthetic Lethality Signatures Uncovered by Genotype-specific CRISPR-Cas9 Screens Sun, N.; Petiwala, S.; Lu, C.; Hutti, J. E.; Hu, M.; Hu, M.; Domanus, M. H.; Mitra, D.; Addo, S. N.; Miller, C. P.; Chung, N. 10.1101/588707 — cancer biology — Posted on 2019-03-26 691 Development of a drug repressible β-catenin mutant mouse to examine effect of activated β-catenin signaling on long-term maintenance of mammary tumor growth Gorman, J. L.; Adams, J. R.; Jones, E. M.; Egan, S. E.; Woodgett, J. R. 10.1101/588459 — cancer biology — Posted on 2019-03-26 692 No evidence that inbreeding avoidance is up-regulated during the ovulatory phase of the menstrual cycle Holzleitner, I. J.; Driebe, J. C.; Arslan, R. C.; Hahn, A. C.; Lee, A. J.; O'Shea, K. J.; Gerlach, T. M.; Penke, L.; Jones, B. C.; DeBruine, L. M. 10.1101/192054 — animal behavior and cognition — Posted on 2019-03-26 693 Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization Lamelza, P.; Young, J. M.; Noble, L. M.; Isakharov, A.; Palanisamy, M.; Rockman, M. V.; Malik, H. S.; Ailion, M. 10.1101/588152 — evolutionary biology — Posted on 2019-03-26 694 Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments. Hafner, A.-S.; Donlin-Asp, P.; Leitch, B.; Herzog, E.; Schuman, E. M. 10.1101/363184 — neuroscience — Posted on 2019-03-26 695 variant2literature: full text literature search for genetic variants Lin, Y.-H.; Lu, Y.-C.; Hsu, J. S.; Lee, K.-H.; Cheng, Y.-W.; Chen, Y.-C.; Chen, T.-F.; Fan, J.-S.; Tu, C.-T.; Hsu, C.-M.; Chou, C.-C.; Chen, P.-L.; Tu, Y.-C. E.; Chen, C.-Y. 10.1101/583450 — genetics — Posted on 2019-03-26 696 Disharmony of the world’s island floras Koenig, C.; Weigelt, P.; Taylor, A.; Stein, A.; Dawson, W.; Essl, F.; Pergl, J.; Pysek, P.; van Kleunen, M.; Winter, M.; Chatelain, C.; Wieringa, J. J.; Krestov, P.; Kreft, H. 10.1101/523464 — ecology — Posted on 2019-03-26 697 Adverse effects of Bacillus thuringiensis bioinsecticide on non-target Drosophila species Babin, A.; Nawrot-Esposito, M.-P.; Gallet, A.; Gatti, J.-L.; Poirie, M. 10.1101/541847 — ecology — Posted on 2019-03-26 698 Exploring the archaeome: detection of archaeal signatures in the human body Pausan, M. R.; Csorba, C.; Singer, G.; Till, H.; Schoepf, V.; Santigli, E.; Klug, B.; Hoegenauer, C.; Blohs, M.; Moissl-Eichinger, C. 10.1101/334748 — microbiology — Posted on 2019-03-26 699 Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence McCulloch, L.; Allan, S. M.; Smith, C. J.; McColl, B. W. 10.1101/587881 — immunology — Posted on 2019-03-26 700 ER-Ca2+ sensor STIM regulates neuropeptides required for development under nutrient restriction in Drosophila M, M.; Wegener, C.; Hasan, G. 10.1101/386649 — developmental biology — Posted on 2019-03-26 701 Comparative genomics guides elucidation of vitamin B12 biosynthesis in novel human associated Akkermansia Kirmiz, N.; Galindo, K.; Cross, K. L.; Luna, E.; Rhoades, N.; Podar, M.; Flores, G. E. 10.1101/587527 — genomics — Posted on 2019-03-26 702 Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13 Kandathil, S. M.; Greener, J. G.; Jones, D. T. 10.1101/586800 — bioinformatics — Posted on 2019-03-26 703 Single particle diffusion characterization by deep learning Granik, N.; Weiss, L. E.; Levine, M.; Chein, M.; Perlson, E.; Roichman, Y.; Shechtman, Y. 10.1101/588533 — biophysics — Posted on 2019-03-26 704 Proteinarium: Multi-Sample Protein-Protein Interaction Visualization and Analysis Tool Armanious, D.; Schuster, J.; Istrail, S.; Padbury, J.; Uzun, A. 10.1101/589085 — bioinformatics — Posted on 2019-03-26 705 Have It, Know It, but Do Not Show It: Examining Physiological Arousal, Anxiety, and Facial Expressions over the Course of a Social Skills Intervention for Autistic Adolescents Jain, N.; Ahamed, S. I.; Bozdag, S.; Dolan, B. K.; McVey, A. J.; Willar, K. S.; Pleiss, S. S.; Murphy, C. C.; Casnar, C. L.; Potts, S.; Cibich, D.; Nelsen-Freund, K.; Fernandez, D.; Hernandez, I.; Van Hecke, A. V. 10.1101/582676 — bioinformatics — Posted on 2019-03-25 706 The distribution of fitness effects among synonymous mutations in a gene under selection Lebeuf-Taylor, E.; McCloskey, N.; Hinz, A.; Bailey, S.; Kassen, R. 10.1101/553610 — evolutionary biology — Posted on 2019-03-25 707 Corticolimbic circuit structure moderates an association between early life stress and later trait anxiety Kim, M. J.; Farber, M. J.; Knodt, A. R.; Hariri, A. R. 10.1101/581926 — neuroscience — Posted on 2019-03-25 708 Scedar: a scalable Python package for single-cell RNA-seq exploratory data analysis Zhang, Y.; Taylor, D. M. 10.1101/375196 — bioinformatics — Posted on 2019-03-25 709 Untapped viral diversity in global soil metagenomes Graham, E. B.; Paez-Espino, D.; Brislawn, C.; Neches, R. Y.; Hofmockel, K. S.; Wu, R.; Kyrpides, N. C.; Jansson, J. K.; McDermott, J. E. 10.1101/583997 — microbiology — Posted on 2019-03-25 710 Transcranial ultrasound selectively biases decision-making in primates Kubanek, J.; Brown, J.; Ye, P.; Pauly, K. B.; Moore, T.; Newsome, W. 10.1101/486134 — neuroscience — Posted on 2019-03-25 711 Emotionotopy: Gradients encode emotion dimensions in right temporo-parietal territories Lettieri, G.; Handjaras, G.; Ricciardi, E.; Leo, A.; Papale, P.; Betta, M.; Pietrini, P.; Cecchetti, L. 10.1101/463166 — neuroscience — Posted on 2019-03-25 712 Co-localization of pain and reduced intra-epidermal nerve fibre density in individuals with HIV-associated sensory neuropathy Patel, I. G.; Kamerman, P. R. 10.1101/587345 — neuroscience — Posted on 2019-03-25 713 NanoR: a user-friendly R package to analyze and compare nanopore sequencing data Bolognini, D.; Bartalucci, N.; Mingrino, A.; Vannucchi, A. M.; Magi, A. 10.1101/514232 — bioinformatics — Posted on 2019-03-25 714 System analysis of cross-talk between nuclear receptors reveals an opposite regulation of the cell cycle by LXR and FXR in human HepaRG liver cells Wigger, L.; Casals Casas, C.; Baruchet, M.; Trang, K. B.; Pradervand, S.; Naldi, A.; Desvergne, B. 10.1101/514976 — physiology — Posted on 2019-03-25 715 Motivation and Cognitive Control in Depression Grahek, I.; Shenhav, A.; Musslick, S.; Krebs, R. M.; Koster, E. H. W. 10.1101/500561 — neuroscience — Posted on 2019-03-25 716 Impact of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S. 10.1101/433011 — evolutionary biology — Posted on 2019-03-25 717 Metacommunity-scale biodiversity regulation and the self-organized emergence of macroecological patterns Dinner O'Sullivan, J. L.; Knell, R. J.; Rossberg, A. G. 10.1101/489336 — ecology — Posted on 2019-03-25 718 Anchoring of actin to the plasma membrane enables tension production in the fission yeast cytokinetic ring Wang, S.; O'Shaughnessy, B. 10.1101/586792 — cell biology — Posted on 2019-03-25 719 Cellular and network mechanisms may generate sparse coding of sequential object encounters in hippocampal-like circuits Trinh, A.-T.; Clarke, S. E.; Harvey-Girard, E.; Maler, L. 10.1101/571414 — neuroscience — Posted on 2019-03-25 720 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C. 10.1101/580670 — neuroscience — Posted on 2019-03-25 721 Metapopulation connectedness and the evolution of multiple life-history traits Masier, S.; Bonte, D. 10.1101/476093 — ecology — Posted on 2019-03-25 722 Nitrogen addition pulse has minimal effect in Wyoming big sagebrush (Artemisia tridentata) communities on the Pinedale Anticline, Wyoming (USA) Beltz, C. W.; Mobley, M. L.; Burke, I. C. 10.1101/446294 — ecology — Posted on 2019-03-25 723 Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 30-day timeline with Dexamethasone exposure. Robinson, J.; Turkington, S.; Abey, S.; Kenea, N.; Henderson, W. 10.1101/355552 — cell biology — Posted on 2019-03-25 724 Membrane bending energy and tension govern mitochondrial division Mahecic, D.; Carlini, L.; Kleele, T.; Colom, A.; Goujon, A.; Matile, S.; Roux, A.; Manley, S. 10.1101/255356 — biophysics — Posted on 2019-03-25 725 Direct visualization of native CRISPR target search in live bacteria reveals Cascade DNA surveillance mechanism Vink, J.; Martens, K.; Vlot, M.; McKenzie, R.; Almendros, C.; Estrada Bonilla, B.; Brocken, D.; Hohlbein, J.; Brouns, S. 10.1101/589119 — microbiology — Posted on 2019-03-25 726 Genomic and phylogenetic analysis of Salmonella Typhimurium and its monophasic variants responsible for invasive endemic infections in Colombia Li, Y.; Pulford, C. V.; Diaz, P.; Perez-Sepulveda, B. M.; Duarte, C.; Predeus, A. V.; Wiesner, M.; Heavens, D.; Low, R.; Schudoma, C.; Lipscombe, J.; Montano, A.; Hall, N.; Moreno, J.; Hinton, J. C. D. 10.1101/588608 — genomics — Posted on 2019-03-25 727 Magnus Representation of Genome Sequences Wu, C.; Ren, S.; Wu, J.; Xia, K. 10.1101/588582 — genomics — Posted on 2019-03-25 728 The role of genetic constraints and social environment in explaining female extra-pair mating Wang, D.; Forstmeier, W.; Martin, K.; Wilson, A.; Kempenaers, B. 10.1101/588475 — evolutionary biology — Posted on 2019-03-25 729 Data Resource Profile:The Dementias Platform UK (DPUK) Data Portal Bauermeister, S.; Orton, C.; Thompson, S.; Barker, R.; Bauermeister, J.; Ben-Shlomo, Y.; Brayne, C.; Burn, D.; Campbell, A.; Calvin, C.; Chandran, S.; Chaturvedi, N.; Chene, G.; Chessell, I.; Corbett, A.; Davis, D.; Denis, M.; DuFouil, C.; Elliott, P.; Fox, N.; Hill, D.; Hofer, S.; Hu, M.; Jindra, C.; Kee, F.; Kim, C.-H.; Kim, C.; Kivimaki, M.; Koychev, I.; Kwan, J.; Lawson, R.; Leroi, I.; Linden, G.; Love, S.; Lovestone, S.; Lyons, R.; MacKay, C.; Matthews, P.; McGuiness, B.; Middleton, L.; Moody, C.; Moore, K.; Na, D. L.; O'Brien, J.; Ourselin, S.; Paranjothy, S.; Park, K. S.; Porteous, D.; 10.1101/582155 — neuroscience — Posted on 2019-03-25 730 Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC Messerschmidt, C.; Obermayer, B.; Klinghammer, K.; Ochsenreither, S.; Treue, D.; Stenzinger, A.; Glimm, H.; Fröhling, S.; Kindler, T.; Brandts, C. H.; Schulze-Osthoff, K.; Weichert, W.; Tinhofer, I.; Klauschen, F.; Keilholz, U.; Beule, D.; Rieke, D. T. 10.1101/586396 — cancer biology — Posted on 2019-03-25 731 The McGill Face Database: validation and insights into the recognition of facial expressions of complex mental states Schmidtmann, G.; Jennings, B. J.; Sandra, D. A.; Pollock, J.; Gold, I. 10.1101/586453 — animal behavior and cognition — Posted on 2019-03-25 732 Direction of gait asymmetry following stroke determines acute response to locomotor task Little, V. L.; Perry, L. A.; Mercado, M. W.; Kautz, S. A.; Patten, C. 10.1101/588103 — neuroscience — Posted on 2019-03-25 733 SVCurator: A Crowdsourcing app to visualize evidence of structural variants for the human genome Chapman, L. M.; Spies, N.; Pai, P.; Lim, C. S.; Carroll, A.; Narzisi, G.; Watson, C. M.; Proukakis, C.; Clarke, W. E.; Nariai, N.; Dawson, E.; Jones, G.; Blankenberg, D.; Brueffer, C.; Xiao, C.; Kolora, S. R. R.; Alexander, N.; Wolujewicz, P.; Ahmed, A.; Smith, G.; Shehreen, S.; Wenger, A. M.; Salit, M.; Zook, J. M. 10.1101/581264 — genomics — Posted on 2019-03-25 734 Beyond early development: observing zebrafish over 6 weeks with hybrid optical and optoacoustic imaging Vetschera, P.; Koberstein-Schwarz, B.; Schmitt-Manderbach, T.; Dietrich, C.; Hellmich, W.; Chekkoury, A.; Symvoulidis, P.; Reber, J.; Westmeyer, G.; Lopez-Schier, H.; Omar, M.; Ntziachristos, V. 10.1101/586933 — biophysics — Posted on 2019-03-25 735 Structural and mutational analysis of the ribosome-arresting human XBP1u Shanmuganathan, V.; Schiller, N.; Magoulopoulou, A.; Cheng, J.; Braunger, K.; Cymer, F.; Berninghausen, O.; Beatrix, B.; Kohno, K.; Heijne, G. v.; Beckmann, R. 10.1101/588681 — biochemistry — Posted on 2019-03-25 736 Cytosolic termini of the FurE transporter regulate endocytosis, pH-dependent gating and specificity Papadaki, G. F.; Lamprinidis, G.; Zamanos, A.; Mikros, E.; Diallinas, G. 10.1101/588368 — molecular biology — Posted on 2019-03-25 737 The CNS in the face of ART contains T cell origin HIV which can lead to drug resistance Lustig, G.; Cele, S.; Karim, F.; Ganga, Y.; Khan, K.; Gosnell, B.; Moosa, Y.; Harrichandparsad, R.; Marais, S.; Gupta, R.; Derache, A.; Giandhari, J.; de Oliveira, T.; Govender, K.; Adamson, J.; Patel, V.; Sigal, A. 10.1101/588426 — microbiology — Posted on 2019-03-25 738 Application of Volumetric Absorptive Micro Sampling to Measure Multidimensional Anti-Influenza Hemagglutinin IgG Antibodies by mPlex-Flu Assay Wang, J.; Li, D.; Wiltse, A.; Emo, J.; Hilchey, S. P.; Zand, M. S. 10.1101/588038 — immunology — Posted on 2019-03-25 739 Acute inflammation is a predisposing factor for weight gain and insulinresistance Oliveira, E. M.; Silva, J. C.; Ascar, T. P.; Sandri, S.; Marchi, A.; Migliorini, S.; Nakaya, H. T. I.; Fock, R.; Campa, A. 10.1101/583773 — cell biology — Posted on 2019-03-25 740 Bioorthogonal non-canonical amino acid tagging reveals translationally active subpopulations of the cystic fibrosis lung microbiota Valentini, T. D.; Lucas, S. K.; Binder, K. A.; Cameron, L. C.; Motl, J. A.; Dunitz, J. M.; Hunter, R. C. 10.1101/588640 — microbiology — Posted on 2019-03-25 741 Polyphosphate initiates tau aggregation through intra- and intermolecular scaffolding Wickramasinghe, S. P.; Lempart, J.; Merens, H. E.; Murphy, J.; Jakob, U.; Rhoades, E. 10.1101/588509 — biophysics — Posted on 2019-03-25 742 Recovery of trait heritability from whole genome sequence data Wainschtein, P.; Jain, D. P.; Yengo, L.; Zheng, Z.; TOPMed Anthropometry Working Group, ; Trans-Omics for Precision Medicine Consortium, ; Cupples, L. A.; Shadyab, A. H.; McKnight, B.; Shoemaker, B. M.; Mitchell, B. D.; Psaty, B. M.; Kooperberg, C.; Roden, D.; Darbar, D.; Arnett, D. K.; Regan, E. A.; Boerwinkle, E.; Rotter, J. I.; Allison, M. A.; McDonald, M.-L. N.; Chung, M. K.; Smith, N. L.; Ellinor, P. T.; Vasan, R. S.; Mathias, R. A.; Rich, S. S.; Heckbert, S. R.; Redline, S.; Guo, X.; Chen, Y.-D. I.; Liu, C.-T.; Andrade, M. d.; Yanek, L. R.; Albert, C. M.; Hernandez, R. D.; McGarvey, S. 10.1101/588020 — genetics — Posted on 2019-03-25 743 HIV-MALARIA CO-INFECTION AND ITS DETERMINANTS AMONG PATIENTS ATTENDING ANTIRETROVIRAL TREATMENT CLINIC IN ZARIA, NORTH-WESTERN NIGERIA Gumel, S. D.; Ibrahim, A.; Olayinka, A.; Ibrahim, M. S.; Balogun, M. S.; Usman, A. D.; Ajayi, I.; Ajumobi, O.; Ahmadu, I.; Song, A.; Maifada, A. I.; Abdullahi, H. 10.1101/588855 — epidemiology — Posted on 2019-03-25 744 An high dose of a conjugated linoleic acid increases fatty liver and insulin resistance in lactating mice HAN, l.; Pang, K. 10.1101/588962 — physiology — Posted on 2019-03-25 745 Prevalence of chronic chikungunya and associated risks factors in the French West Indies (La Martinique). A prospective cohort study Antoine, B.; Thioune, M.; Abel, S.; Belrosse, G.; Calmont, I.; Cesaire, R.; Cervantes, M.; Fagour, L.; Javelle, E.; Lebris, C.; Najioullah, F.; Pierre-Francois, S.; Roze, B.; Vigan, M.; Laouenan, C.; Cabie, A.; Bally J, Brouste Y, Brunier L, Godaert-Simon L, Ho, 10.1101/588970 — microbiology — Posted on 2019-03-25 746 Taxonomic and functional anuran beta diversity of the subtropical metacommunity respond differentially to environmental and spatial predictors Dalmolin, D. A.; Ramos Pereira, M. J. V. d. C.; Tozetti, A. M. 10.1101/588947 — ecology — Posted on 2019-03-25 747 Nilotinib, an approved leukemia drug, inhibits Smoothened signaling in Hedgehog-dependent medulloblastoma Chahal, K. K.; Li, J.; Kufareva, I.; Parle, M.; Durden, D. D.; Wechsler-Reya, R.; Chen, C. C.; Abagyan, R. 10.1101/588897 — cancer biology — Posted on 2019-03-25 748 MgO nanoparticles coated with Polyethylene Glycol as carrier for 2-Methoxyestradiol anticancer drug. Alfaro, A.; Leon, A.; Guajardo, E.; Reuquen, P.; Torres, F.; Mery, M.; Segura, R.; Zapata, P.; orihuela, p. 10.1101/588939 — cancer biology — Posted on 2019-03-25 749 Study on the Health Communication Behavior of Chinese Doctors on Network Media----Based on the Empirical Investigation of 119 Chinese Doctors Hu, F.; Wang, P. 10.1101/588863 — scientific communication and education — Posted on 2019-03-25 750 De novo transcriptome assembly of the African bullfrog Pyxicephalus adspersus for molecular analysis of aestivation Yoshida, N.; Kaito, C. 10.1101/588889 — molecular biology — Posted on 2019-03-25 751 Extensive adaptive immune response of AAVs and Cas proteins in non-human primates Chen, Y.; Xiao, P.; Bai, R.; Zhang, T.; Zhou, Y.; Zhou, Z.; Zhuo, Y.; Gong, N.; Liu, J.; Ren, S.; Wu, R.; Shen, B.; Li, S.; Niu, Y.; Ji, W. 10.1101/588913 — immunology — Posted on 2019-03-25 752 Polymorphisms in the vitamin D system and mortality - The Tromso study Jorde, R.; Wilsgaard, T.; Grimnes, G. 10.1101/588871 — genetics — Posted on 2019-03-25 753 Information decomposition of multichannel EMG to map functional interactions in the distributed motor system Boonstra, T. W.; Faes, L.; Kerkman, J. N.; Marinazzo, D. 10.1101/587949 — neuroscience — Posted on 2019-03-25 754 Inter-joint and temporal coordination change in very slow walking Little, V. L.; McGuirk, T. E.; Patten, C. 10.1101/588095 — neuroscience — Posted on 2019-03-25 755 Analyzing dynamic decision-making models using Chapman-Kolmogorov equations Barendregt, N. W.; Josic, K.; Kilpatrick, Z. 10.1101/588087 — neuroscience — Posted on 2019-03-25 756 Cryptic asexual reproduction in Caenorhabditis nematodes revealed by interspecies hybridization Lamelza, P.; Young, J. M.; Noble, L. M.; Isakharov, A.; Palanisamy, M.; Rockman, M. V.; Malik, H. S.; AILION, M. 10.1101/588152 — evolutionary biology — Posted on 2019-03-25 757 Segregation of floricolous ants along latitudinal and urbanization gradients Vergnes, A.; Rome, Q.; Gayral, I.; Fontaine, C. 10.1101/588186 — ecology — Posted on 2019-03-25 758 SSVEP as a no-report paradigm to capture phenomenal experience of complex visual images de Heering, A.; Beauny, A.; Vuillaume, L.; Salvesen, L.; Cleeremans, A. 10.1101/588236 — neuroscience — Posted on 2019-03-25 759 Ubiquinone biosynthesis over the entire O2 range: characterization of a conserved, O2-independent pathway Pelosi, L.; Vo, C.-D.-T.; Abby, S.; Loiseau, L.; Rascalou, B.; Hajj Chehade, M.; Faivre, B.; Gousse, M.; Chenal, C.; Touati, N.; Binet, L.; Cornu, D.; Fyfe, C. D.; Fontecave, M.; Barras, F.; Murielle, L.; Pierrel, F. 10.1101/587956 — microbiology — Posted on 2019-03-25 760 Genomic acquisitions in emerging populations of Xanthomonas vasicola pv. vasculorum infecting corn in the U.S. and Argentina Perez Quintero, A. L.; Ortiz-Castro, M.; Wu, G.; Lang, J. M.; Liu, S.; Chapman, T. A.; Chang, C.; Ziegle, J.; Peng, Z.; White, F. F.; Plazas, M. C.; Leach, J. E.; Broders, K. 10.1101/587915 — microbiology — Posted on 2019-03-25 761 Predicting Drug Protein Interaction using Quasi-Visual Question Answering System Zheng, S.; Li, Y.; Chen, S.; Xu, J.; Yang, Y. 10.1101/588178 — bioinformatics — Posted on 2019-03-25 762 Context-dependent limb movement encoding in neuronal populations of motor cortex Omlor, W.; Sipilae, P.; Wahl, A.-S.; Luetcke, H.; Laurenczy, B.; Chen, I.-W.; Sumanovski, L. T.; van 't Hoff, M.; Bethge, P.; Voigt, F. F.; Schwab, M. E.; Helmchen, F. 10.1101/588129 — neuroscience — Posted on 2019-03-25 763 Lower Extremity Long-Latency Reflexes Differentiate Walking Function After Stroke Banks, C. L.; Little, V. L.; Walker, E. R.; Patten, C. 10.1101/588111 — neuroscience — Posted on 2019-03-25 764 Mouse vendor influence on the bacterial and viral gut composition exceeds the effect of diet Rasmussen, T. S.; de Vries, L.; Kot, W.; Hansen, L. H.; Castro-Mejia, J. L.; Vogensen, F. K.; Hansen, A. K.; Nielsen, D. S. 10.1101/588160 — microbiology — Posted on 2019-03-25 765 Neutral genomic signatures of host-parasite coevolution. Zivkovic, D.; John, S.; Verin, M.; Stephan, W.; Tellier, A. 10.1101/588202 — evolutionary biology — Posted on 2019-03-25 766 Co-localization of pain and reduced intra-epidermal nerve fibre density in individuals with HIV-associated sensory neuropathy Patel, I. G.; Kamerman, P. 10.1101/587345 — neuroscience — Posted on 2019-03-25 767 Characterizing the adaptive potential of north-western Pacific reef corals to empower conservation strategies: a role for seascape genomics Selmoni, O.; Veronique, B.-L.; Lecellier, G.; Joost, S. 10.1101/588228 — evolutionary biology — Posted on 2019-03-25 768 Cerebellar involvement in learning to balance a cart-pole system Ludolph, N.; Ernst, T. M.; Mueller, O. M.; Goericke, S. L.; Giese, M. A.; Timmann, D.; Ilg, W. 10.1101/586990 — neuroscience — Posted on 2019-03-25 769 A novel averaging principle provides insights in the impact of intratumoral heterogeneity on tumor progression Leocata, M.; Lopez Alfonso, J. C.; Kavallaris, N.; Hatzikirou, H. 10.1101/584490 — systems biology — Posted on 2019-03-25 770 Neuroanatomical Correlates In Bilinguals: The Case Of Children And Elderly Garcia-Penton, L.; Fernandez, Y.; Dunabeitia, J. A.; Perez, A.; Carreiras, M. 10.1101/586768 — neuroscience — Posted on 2019-03-25 771 Cyclophilin A protects HIV-1 from restriction by human TRIM5α Kim, K.; Dauphin, A.; Komurlu, S.; Yurkovetskiy, L.; Diehl, W. E.; McCauley, S. M.; Carbone, C.; Selyutina, A.; Bulnes-Ramos, A.; Diaz-Griffero, F.; Strambio-De-Castillia, C.; Campbell, E. M.; Luban, J. 10.1101/587907 — microbiology — Posted on 2019-03-25 772 Yellow Fever Vaccine Protects Resistant and Susceptible Mice Against Zika Virus Infection Vicente, A. C.; Guedes-da-Silva, F. H.; Dumard, C. H.; Ferreira, V. N. S.; da Costa, I. P. S.; Machado, R. A.; Barros-Aragao, F. G. Q.; Neris, R. L. S.; Dos-Santos, J. S.; Assuncao-Miranda, I.; Figueiredo, C. P.; Dias, A. A.; Gomes, A. M. O.; de Matos Guedes, H. L.; Oliveira, A. C.; Silva, J. L. 10.1101/587444 — immunology — Posted on 2019-03-25 773 Proteomics analysis of extracellular matrix remodeling during zebrafish heart regeneration Garcia-Puig, A.; Mosquera, J. L.; Jimenez-Delgado, S.; Garcia-Pastor, C.; Jorba, I.; Navajas, D.; Canals, F.; Raya, A. 10.1101/588251 — developmental biology — Posted on 2019-03-25 774 MuStARD: Deep Learning for intra- and inter-species scanning of functional genomic patterns Georgakilas, G. K.; Grioni, A.; Liakos, K. G.; Malanikova, E.; Plessas, F. C.; Alexiou, P. 10.1101/547679 — bioinformatics — Posted on 2019-03-25 775 HAVE IT, KNOW IT, BUT DO NOT SHOW IT: EXAMINING PHYSIOLOGICAL AROUSAL, ANXIETY, AND FACIAL EXPRESSIONS OVER THE COURSE OF A SOCIAL SKILLS INTERVENTION FOR AUTISTIC ADOLESCENTS Jain, N.; Ahamed, S. I.; Bozdag, S.; Dolan, B. K.; McVey, A. J.; Willar, K. S.; Pleiss, S. S.; Murphy, C. C.; Casnar, C. L.; Potts, S.; Cibich, D.; Nelsen-Freund, K.; Fernandez, D.; Hernandez, I.; Van Hecke, A. V. 10.1101/582676 — bioinformatics — Posted on 2019-03-25 776 A new cryo-EM system for electron 3D crystallography by eEFD Yonekura, K.; Ishikawa, T.; Maki-Yonekura, S. 10.1101/588046 — molecular biology — Posted on 2019-03-25 777 AluMine: alignment-free method for the discovery of polymorphic Alu element insertions Puurand, T.; Kukushkina, V.; Pajuste, F.-D.; Remm, M. 10.1101/588434 — genomics — Posted on 2019-03-25 778 Global biogeographical regions of freshwater fish species Leroy, B.; Dias, M. S.; Giraud, E.; Hugueny, B.; Jezequel, C.; Leprieur, F.; Oberdorff, T.; Tedesco, P. A. 10.1101/319566 — ecology — Posted on 2019-03-25 779 Multiscale analysis of acne connects molecular subnetworks with disease status Hall, J. B.; Divaraniya, A. A.; Lee, H.-C.; Becker, C. E.; McCauley, B.; Glowe, P. K.; Sebra, R.; Pavel, A. B.; Singer, G.; Nelson, A.; Thiboutot, D.; Marmur, E.; Schadt, E. E.; Zeichner, J.; Guttman-Yassky, E.; Kidd, B. A.; Dudley, J. T. 10.1101/587857 — systems biology — Posted on 2019-03-25 780 Ontogeny and expression profiles of steroid hormone receptors in a mouse model of endometriosis Mishra, A.; Galvankar, M.; Singh, N.; Vaidya, S.; Chaudhari, U.; Modi, D. 10.1101/588392 — pathology — Posted on 2019-03-25 781 Do questionnaires reflect their purported cognitive functions? Clark, I. A.; Maguire, E. A. 10.1101/583690 — neuroscience — Posted on 2019-03-25 782 Inter-subject pattern analysis: a straightforward and powerful scheme for group-level MVPA. Wang, Q.; Cagna, B.; Chaminade, T.; Takerkart, S. 10.1101/587899 — neuroscience — Posted on 2019-03-25 783 Differential dynamics of microbial community networks help identify microorganisms interacting with residue-borne pathogens: the case of Zymoseptoria tritici in wheat Kerdraon, L.; Barret, M.; Laval, V.; Suffert, F. 10.1101/587667 — microbiology — Posted on 2019-03-25 784 Adult Drosophila Muscle Morphometry through MicroCT reveals dynamics during aging Chaturvedi, D.; Prabhakar, S.; Aggarwal, A.; VijayRaghavan, K. 10.1101/587733 — developmental biology — Posted on 2019-03-25 785 Stringent structural plasticity of dendritic spines revealed by two-photon glutamate uncaging in adult mouse neocortex in vivo Noguchi, J.; Nagaoka, A.; Hayama, T.; Ucar, H.; Yagishita, S.; Takahashi, N.; Kasai, H. 10.1101/577742 — neuroscience — Posted on 2019-03-25 786 Encoding Variability: When Pattern Reactivation Does Not Benefit Context Memory Sievers, C.; Smith, F. W.; Saada, J.; Simons, J. S.; Renoult, L. 10.1101/586446 — neuroscience — Posted on 2019-03-25 787 Morphological variation in Blommersia pelvic shape coincides with muscular architecture and parallels genus phylogenetic evolution Santos-Santos, J. H.; Guinovart-Castan, M.; Vieites, D. 10.1101/586248 — evolutionary biology — Posted on 2019-03-25 788 The mechanisms of dynamin-actin interaction Zhang, R.; Gerassimov, N.; Lee, D. M.; Jimah, J. R.; Kim, S.; Luvsanjav, D.; Winkelman, J.; Mettlen, M.; Abrams, M. E.; Kalia, R.; Keene, P.; Pandey, P.; Ravaux, B.; Kim, J. H.; Ditlev, J. A.; Zhang, G.; Rosen, M. K.; Frost, A.; Alto, N. M.; Gardel, M.; Schmid, S. L.; Hinshaw, J. E.; Chen, E. H. 10.1101/586461 — cell biology — Posted on 2019-03-25 789 Fully-sensitive Seed Finding in Sequence Graphs Using a Hybrid Index Ghaffaari, A.; Marschall, T. 10.1101/587717 — bioinformatics — Posted on 2019-03-25 790 In vivo feasibility study of the use of porous polyhedral oligomeric silsesquioxane implants in partial laryngeal reconstruction. Birchall, M. A.; Hermann, P.; Sibbons, P. 10.1101/587691 — bioengineering — Posted on 2019-03-25 791 Co-developing climate services for public health: stakeholder needs and perceptions for the prevention and control of Aedes-transmitted diseases in the Caribbean. Stewart-Ibarra, A. M.; Romero, M.; Hinds, A. Q. J.; Lowe, R.; Mahon, R.; Van Meerbeeck, C. J.; Rollock, L.; Gittens-St. Hillaire, M.; St. Ville, S.; Ryan, S. J.; Trotman, A. R.; Borbor-Cordova, M. J. 10.1101/587188 — scientific communication and education — Posted on 2019-03-25 792 Human lateral Frontal Pole contributes to control over social-emotional behaviour Bramson, B.; Folloni, D.; Verhagen, L.; Hartogsveld, B.; Mars, R. B.; Toni, I.; Roelofs, K. 10.1101/584896 — neuroscience — Posted on 2019-03-25 793 Carrion flies as sentinels for monitoring rabbit calicivirus activity in Australia Hall, R. N.; Huang, N.; Roberts, J. M. K.; Strive, T. 10.1101/585885 — microbiology — Posted on 2019-03-25 794 A seventeenth-century Mycobacterium tuberculosis genome supports a Neolithic emergence of the Mycobacterium tuberculosis complex Sabin, S.; Herbig, A.; Vagene, A. J.; Ahlström, T.; Bozovic, G.; Arcini, C.; Kühnert, D.; Bos, K. I. 10.1101/588277 — genomics — Posted on 2019-03-25 795 GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traits Zhao, B.; Luo, T.; Li, T.; Li, Y.; Zhang, J.; Shan, Y.; Wang, X.; Yang, L.; Zhou, F.; Zhu, Z.; Zhu, H. 10.1101/586339 — genetics — Posted on 2019-03-25 796 Extraordinary claims require extraordinary evidence in the case of asserted mtDNA biparental inheritance Salas, A.; Schoenherr, S.; Bandelt, H. J.; Gomez-Carballa, A.; Weissensteiner, H. 10.1101/585752 — genetics — Posted on 2019-03-25 797 Genome-wide association study of Parkinson's disease progression biomarkers in 12 longitudinal patients' cohorts Iwaki, H.; Blauwendraat, C.; Leonard, H. L.; Kim, J. J.; Liu, G.; Maple-Grodem, J.; Corvol, J.-C.; Pihlstrom, L.; van Nimwegen, M.; Hutten, S. J.; Nguyen, K.-D. H.; Rick, J.; Eberly, S.; Faghri, F.; Auinger, P.; Scott, K. M.; Wijeyekoon, R.; Van Deerlin, V. M.; Hernandez, D.; Gibbs, J. R.; Chitrala, K. N.; Day-Williams, A. G.; Brice, A.; Alves, G.; Noyce, A. J.; Tysnes, O.-B.; Evans, J.; Breen, D. P.; Estrada, K.; Wegel, C. E.; Danjou, F.; Simon, D. K.; Andreassen, O. A.; Ravina, B.; Toft, M.; Heutink, P.; Bloem, B. R.; Weintraub, D.; Barker, R. A.; Williams-Gray, C. H.; van de Warrenburg, B. 10.1101/585836 — genetics — Posted on 2019-03-25 798 On the move: Redox-dependent protein relocation Foyer, C. H.; Baker, A.; Wright, M.; Sparkes, I.; Mhamdi, A.; Van Breusegem, F.; Schippers, J. 10.1101/588269 — cell biology — Posted on 2019-03-25 799 tailfindr: Alignment-free poly(A) length measurement for Oxford Nanopore RNA and DNA sequencing Krause, M.; Niazi, A. M.; Labun, K.; Müller, F. S.; Torres Cleuren, Y. N.; Valen, E. 10.1101/588343 — bioinformatics — Posted on 2019-03-25 800 Characterization of pathology-inducing α-synuclein species from human diseased brain tissue Graef, J. D.; Hoque, N.; Polson, C.; Yang, L.; Iben, L.; Cao, Y.; Devidze, N.; Ahlijanian, M. K.; Meredith, J. 10.1101/588335 — neuroscience — Posted on 2019-03-25 801 Enriching hippocampal memory function in older adults through video games Clemenson, G. D.; Stark, S. M.; Rutledge, S. M.; Stark, C. E. 10.1101/587006 — neuroscience — Posted on 2019-03-25 802 Prenatal Exposure to Environmental Chemicals Modulates Serum Phospholipids in Newborn Infants, Increasing Later Risk of Type 1 Diabetes McGlinchey, A.; Sinioja, T.; Lamichhane, S.; Bodin, J.; Siljander, H.; Geng, D.; Carlsson, C.; Duberg, D.; Ilonen, J.; Virtanen, S. M.; Dirven, H.; Bentsen, H. F.; Zimmer, K.; Nygaard, U. C.; Oresic, M.; Knip, M.; Hyotylainen, T. 10.1101/588350 — molecular biology — Posted on 2019-03-25 803 First record of the endophytic bacteria of Deschampsia antarctica E. Desv. from two distant localities of the maritime Antarctica Podolich, O.; Parnikoza, I.; Voznyuk, T.; Zubova, G.; Zaets, I.; Miryuta, N.; Myryuta, G.; Poronnik, O.; Kozeretska, I.; Kunakh, V.; Pirttila, A.-M.; Kozyrovska, N. 10.1101/586099 — microbiology — Posted on 2019-03-25 804 Treatment of Murine Lupus with TIGIT-Ig Liu, S.; Sun, L.; Wang, C.; Cui, Y.; Ling, Y.; Li, T.; Lin, F.; Fu, W.; Ding, M.; Zhang, S.; Lei, C.; Hu, S. 10.1101/586321 — immunology — Posted on 2019-03-25 805 Childhood intelligence attenuates the association between biological ageing and health outcomes in later life Stevenson, A. J.; McCartney, D. L.; Hillary, R. F.; Redmond, P.; Taylor, A. M.; Zhang, Q.; McRae, A. F.; Spires-Jones, T. L.; McIntosh, A. M.; Deary, I. J.; Marioni, R. E. 10.1101/588293 — genomics — Posted on 2019-03-25 806 Increased genetic marker density reveals high levels of admixture between red deer and introduced sika in Kintyre, Scotland McFarlane, S. E.; Hunter, D. C.; Senn, H. V.; Smith, S. L.; Holland, R.; Huisman, J.; Pemberton, J. M. 10.1101/588327 — evolutionary biology — Posted on 2019-03-25 807 Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia Milne, P.; Wilhelm-Benartzi, C.; Grunwald, M. R.; Bigley, V.; Publicover, A.; Pagan, S.; Marr, H.; Jones, G.; Dickinson, A.; Grech, A.; Burnett, A.; Russell, N.; Levis, M.; Knapper, S.; Collin, M. 10.1101/588319 — cancer biology — Posted on 2019-03-25 808 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov. Studholme, D. J.; Wicker, E.; Aspin, A.; Bogdanove, A.; Broders, K.; Dubrow, Z.; Grant, M.; Jones, J. B.; Karamura, G.; Lang, J.; Leach, J.; Abrare, S. M.; Mahuku, G.; Nakato, G. V.; Coutinho, T.; Smith, J.; Bull, C. 10.1101/571166 — microbiology — Posted on 2019-03-25 809 Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B Vögtle, T.; Sharma, S.; Mori, J.; Nagy, Z.; Semeniak, D.; Geer, M. J.; Smith, C. W.; Lane, J.; Pollack, S.; Lassila, R.; Jouppila, A.; Barr, A. J.; Ogg, D. J.; Howard, T. D.; McMiken, H. J.; Warwicker, J.; Geh, C.; Rowlinson, R.; Abbott, W. M.; Schulze, H.; Wright, G. J.; Mazharian, A.; Fütterer, K.; Rajesh, S.; Douglas, M. R.; Senis, Y. A. 10.1101/584698 — biochemistry — Posted on 2019-03-25 810 Transcriptional crosstalk varies between regulatory strategies Grah, R.; Friedlander, T. 10.1101/372672 — systems biology — Posted on 2019-03-25 811 Detecting RyR clusters with CaCLEAN: influence of spatial distribution and structural heterogeneity Ladd, D.; Tilunaite, A.; Soeller, C.; Roderick, H. L.; Crampin, E.; Rajagopal, V. 10.1101/549683 — bioengineering — Posted on 2019-03-25 812 The functional repertoire encoded within the native microbiome of the model nematode Caenorhabditis elegans Zimmermann, J.; Obeng, N.; Yang, W.; Pees, B.; Petersen, C.; Waschina, S.; Kissoyan, K. A.; Aidley, J.; Hoeppner, M. P.; Bunk, B.; Sproer, C.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H. 10.1101/554345 — microbiology — Posted on 2019-03-25 813 The convoluted evolutionary history of the capped-golden langur lineage (Cercopithecidae: Colobinae)- concatenation versus coalescent analyses Arekar, K.; Parigi, A.; Karanth, K. P. 10.1101/508929 — evolutionary biology — Posted on 2019-03-25 814 WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling Song, Z.; Sun, X.; Xia, Z.; Jia, Y.; Zhu, J.; Fang, C.; Yang, H.; Wang, J. 10.1101/575100 — bioinformatics — Posted on 2019-03-25 815 CRK2 enhances salt tolerance by regulating callose deposition in connection with PLDα1 Hunter, K.; Kimura, S.; Rokka, A.; Tran, C.; Toyota, M.; Kukkonen, J.; Wrzaczek, M. 10.1101/487009 — plant biology — Posted on 2019-03-25 816 High precision automated detection of labeled nuclei in Gigapixel resolution image data of Mouse Brain Das, S.; Jayakumar, J.; Bannerjee, S.; Ramaswamy, J.; Vangala, V.; Ram, K.; Mitra, P. P. 10.1101/252247 — neuroscience — Posted on 2019-03-25 817 Widespread methane formation by Cyanobacteria in aquatic and terrestrial ecosystems Bizic-Ionescu, M.; Klintzch, T.; Ionescu, D.; Hindiyeh, M. Y.; Guenthel, M.; Muro Pastor, A. M.; Eckert, W.; Keppler, F.; Grossart, H.-P. 10.1101/398958 — microbiology — Posted on 2019-03-25 818 The inducible response of the nematode Caenorhabditis elegans to members of its natural microbiome across development and adult life Yang, W.; Petersen, C.; Pees, B.; Zimmermann, J.; Waschina, S.; Dirksen, P.; Rosenstiel, P.; Tholey, A.; Leippe, M.; Dierking, K.; Kaleta, C.; Schulenburg, H. 10.1101/554758 — evolutionary biology — Posted on 2019-03-25 819 Model-based assessment of public health impact and cost-effectiveness of dengue vaccination following screening for prior exposure Espana, G.; Yao, Y.; Anderson, K. B.; Fitzpatrick, M. C.; Smith, D. L.; Morrison, A. C.; Wilder-Smith, A.; Scott, T. W.; Perkins, A. 10.1101/367060 — epidemiology — Posted on 2019-03-25 820 MEXCOWalk: Mutual Exclusion and Coverage Based Random Walk to Identify Cancer Modules Ahmed, R.; Baali, I.; Erten, C.; Hoxha, E.; Kazan, H. 10.1101/547653 — bioinformatics — Posted on 2019-03-25 821 Fast and flexible simulation and parameter estimation for synthetic biology using bioscrape Swaminathan, A.; Poole, W.; Hsiao, V.; Murray, R. M. 10.1101/121152 — synthetic biology — Posted on 2019-03-25 822 Phenotyping and molecular marker analysis of WH1105 and Kharchia 65 backcrosses and F4 progenies for salinity tolerance Varsha, V.; Yashveer, S.; Singh, V.; Pratap, S. 10.1101/586941 — plant biology — Posted on 2019-03-24 823 The effects of cerebellar transcranial direct current stimulation on the cognitive stage of sequence learning Ballard, H. K.; Goen, J. R. M.; Maldonado, T.; Bernard, J. A. 10.1101/588012 — neuroscience — Posted on 2019-03-24 824 NSD2 overexpression drives clustered chromatin and transcriptional changes in insulated domains Lhoumaud, P.; Badri, S.; Rodriguez-Hernaez, J.; Sethia, G.; Kloetgen, A.; Cornwell, M.; Bhattacharyya, S.; Ay, F.; Bonneau, R.; Tsirigos, A.; Skok, J. A. 10.1101/587931 — genomics — Posted on 2019-03-24 825 Single-step genome-wide association study for resistance to Piscirickettsia salmonis in rainbow trout (Oncorhynchus mykiss) Marin Nahuelpi, R. I.; Barria, A.; Caceres Refusta, P.; Lopez, M.-E.; Bassini, L.; Lhorente Caussade, J. P.; Yanez, J. M. 10.1101/587535 — genomics — Posted on 2019-03-24 826 Peaceful behaviour: a strategy employed by an obligate nest invader to avoid conflict with its host species Hugo, H.; Cristaldo, P. F.; DeSouza, O. 10.1101/587592 — animal behavior and cognition — Posted on 2019-03-24 827 MS Atlas - A molecular map of brain lesion stages in progressive multiple sclerosis Frisch, T.; Elkjaer, M. L.; Reynolds, R.; Michel, T. M.; Kacprowski, T.; Burton, M.; Kruse, T. A.; Thomassen, M.; Baumbach, J.; Illes, Z. 10.1101/584920 — systems biology — Posted on 2019-03-24 828 Modulation of visual cortex by hippocampal signals Fournier, J.; Saleem, A. B.; Diamanti, E. M.; Wells, M. J.; Harris, K. D.; Carandini, M. 10.1101/586917 — neuroscience — Posted on 2019-03-24 829 Bidirectional FtsZ filament treadmilling promotes membrane constriction via torsional stress Ramirez-Diaz, D. A.; Merino-Salomon, A.; Heymann, M.; Schwille, P. 10.1101/587790 — biophysics — Posted on 2019-03-24 830 Genetic dissection of cell wall defects and the strigolactone pathway in Arabidopsis. Ramirez, V.; Pauly, M. 10.1101/586388 — plant biology — Posted on 2019-03-24 831 On the relationship between LFP beta oscillation amplitude and firing rate of individual neurons in monkey motor cortex Confais, J.; Malfait, N.; Brochier, T.; Riehle, A.; Kilavik, B. E. 10.1101/586727 — neuroscience — Posted on 2019-03-24 832 Codon Optimality Confers GC-Rich-Induced Stability to mRNAs in Humans Hia, F.; Yang, S. F.; Shichino, Y.; Yoshinaga, M.; Murakawa, Y.; Vandenbon, A.; Fukao, A.; Fujiwara, T.; Landthaler, M.; Natsume, T.; Adachi, S.; Iwasaki, S.; Takeuchi, O. 10.1101/585992 — molecular biology — Posted on 2019-03-24 833 ANP32A and ANP32B are key factors in the Rev dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA Wang, Y.; Zhang, H.; Na, L.; Du, C.; Zhang, Z.; Zheng, Y.; Wang, X. 10.1101/559096 — microbiology — Posted on 2019-03-24 834 Machine Learning-Assisted Digital PCR and Melt Enables Broad Bacteria Identification and Pheno-Molecular Antimicrobial Susceptibility Test Athamanolap, P.; Hsieh, K.; O'Keefe, C. M.; Zhang, Y.; Yang, S.; Wang, J. 10.1101/587543 — bioengineering — Posted on 2019-03-24 835 The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell autonomous level and by collaborative exclusion Lopez-Jimenez, A. T.; Hagedorn, M.; Delince, M. J.; McKinney, J.; Soldati, T. 10.1101/586263 — microbiology — Posted on 2019-03-24 836 Molecular dissection of the structural and nonstructural proteins of spanish-1918 Influenza, pandemic-2009, and bird flu viruses Mahardika, G. N.; Suartha, N. I.; Kencana, Y. G. A.; Suardana, I. B. K.; Budayanti, N. S. 10.1101/585778 — microbiology — Posted on 2019-03-24 837 A multi-omic cohort as a reference point for promoting a healthy human gut microbiome Jie, Z.; Liang, S.; Ding, Q.; Tang, S.; Li, F.; Wang, D.; Lin, Y.; Chen, P.; Cai, K.; Rao, W.; Liao, Y.; Zhou, D.; Qiu, X.; Chen, X.; Zi, J.; Wang, X.; Zhang, W.; Zhang, T.; Xiao, L.; Yang, H.; Wang, J.; Hou, Y.; Liu, X.; Kristiansen, K.; Zhong, H.; Jia, H.; Xu, X. 10.1101/585893 — microbiology — Posted on 2019-03-24 838 Supervised dimension reduction for large-scale \"omics\" data with censored survival outcomes under possible non-proportional hazards Spirko-Burns, L.; Devarajan, K. 10.1101/586529 — bioinformatics — Posted on 2019-03-24 839 Automated reconstruction of all gene histories in large bacterial pangenome datasets and search for co-evolved gene modules with Pantagruel Lassalle, F.; Veber, P.; Jauneikaite, E.; Didelot, X. 10.1101/586495 — bioinformatics — Posted on 2019-03-24 840 Inhibition of arterivirus RNA synthesis by cyclophilin inhibitors is counteracted by mutations in replicase transmembrane subunits De Wilde, A. H.; Boomaars-van der Zanden, L.; de Jong, A. W. M.; Barcena, M.; Snijder, E. J.; Posthuma, C. C. 10.1101/587261 — microbiology — Posted on 2019-03-24 841 Generic and context-dependent gene modulations during Hydra whole body regeneration Galliot, B.; Wenger, Y.; Buzgariu, W.; Perruchoud, C.; Loichot, G. 10.1101/587147 — developmental biology — Posted on 2019-03-24 842 Modeling the ballistic-to-diffusive transition in nematode motility reveals variation in exploratory behavior across species Helms, S. J.; Rozemuller, W. M.; Costa, A. C.; Avery, L.; Stephens, G. J.; Shimizu, T. S. 10.1101/587618 — biophysics — Posted on 2019-03-24 843 Negative calorie foods: An empirical examination of what is fact or fiction Buddemeyer, K. M.; Alexander, A. E.; Secor, S. M. 10.1101/586958 — physiology — Posted on 2019-03-24 844 Anatomo-functional correlates of auditory development in infancy Adibpour, P.; Lebenberg, J.; Kabdebon, C.; Dehaene-Lambertz, G.; Dubois, J. 10.1101/585448 — neuroscience — Posted on 2019-03-24 845 Identification of blaGIM-1 in Acinetobacter variabilis isolated from the hospital environment in Tamil Nadu, India Manohar, P.; Ragavi, M.; Augustine, A.; MV, H.; Nachimuthu, R. 10.1101/586164 — microbiology — Posted on 2019-03-24 846 Vesicle-associated Pseudomonas aeruginosa leucine aminopeptidase modulates bacterial biofilms grown on host cellular substrates Esoda, C.; Kuehn, M. 10.1101/587279 — microbiology — Posted on 2019-03-24 847 Identifying suitable Listeria innocua strains as surrogates for Listeria monocytogenes for horticultural products Mohan, V.; Wibisono, R.; de Hoop, L.; Summers, G.; Fletcher, G. C. 10.1101/586016 — microbiology — Posted on 2019-03-24 848 Global Modulation in DNA Epigenetics during Pro-Inflammatory Macrophage Activation JAIN, N.; Shahal, T.; Gabrieli, T.; Gilat, N.; Torchinsky, D.; Michaeli, Y.; VOGEL, V.; Ebenstein, Y. 10.1101/587311 — immunology — Posted on 2019-03-24 849 Comparative genomics guides elucidation of vitamin B12 biosynthesis in novel human associated Akkermansia Kirmiz, N.; Galindo, K.; Cross, K.; Luna, E.; Rhoades, N.; Podar, M.; Flores, G. 10.1101/587527 — genomics — Posted on 2019-03-24 850 Genetic dissection of the redundant and divergent functions of histone chaperone paralogs in yeast Savic, N.; Shortill, S.; Bilenky, M.; Dilworth, D.; Hirst, M.; Nelson, C. J. 10.1101/586347 — genetics — Posted on 2019-03-24 851 The planktonic protist interactome: emerging trends after a century of research Bjorbaekmo, M. F. M.; Evenstad, A.; Rosaeg, L. L.; Krabberod, A. K.; Logares, R. 10.1101/587352 — ecology — Posted on 2019-03-24 852 From bud formation to flowering: transcriptomic state defines the cherry developmental phases of sweet cherry bud dormancy Vimont, N.; Fouche, M.; Campoy, J. A.; Tong, M.; Arkoun, M.; Yvin, J.-C.; Wigge, P. A.; Dirlewanger, E.; Cortijo, S.; Wenden, B. 10.1101/586651 — plant biology — Posted on 2019-03-24 853 Meningitis pathogens evade immune responses by thermosensing Eichner, H.; Spelmink, L.; Pathak, A.; Henriques Normark, B.; Loh, E. 10.1101/586131 — microbiology — Posted on 2019-03-24 854 A tissue-like platform for studying engineered quiescent human T-cells’ interactions with dendritic cells Abu-Shah, E.; Demetriou, P.; Mayya, V.; Balint, S.; Kutuzov, M. A.; Dushek, O.; Dustin, M. L. 10.1101/587386 — immunology — Posted on 2019-03-24 855 NOD1 mediates non-canonical inflammasome processing of interleukin-18 in epithelial cells to Helicobacter pylori infection. Tran, L. S.; Ying, L.; D'Costa, K.; Wray-McCann, G.; Kerr, G.; Le, L.; Allison, C. C.; Ferrand, J.; Chaudhry, H.; Emery, J.; De Paoli, A.; Creed, S.; Kaparakis-Liaskos, M.; Como, J.; Dowling, J.; Johanesen, P. A.; Kufer, T. A.; Pedersen, J. S.; Mansell, A.; Philpott, D. J.; Elgass, K.; Abud, H. E.; Nachbur, U.; Croker, B. A.; Masters, S. L.; Ferrero, R. L. 10.1101/587212 — immunology — Posted on 2019-03-24 856 Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis Chang, H.-H.; Ho, C.-H.; Tomita, B.; Silva, A. A.; Sparks, J. A.; Karlson, E. W.; Rao, D. A.; Lee, Y. C.; Ho, I.-C. 10.1101/586982 — immunology — Posted on 2019-03-24 857 Membrane association of VAMP2 SNARE motif in cells and its regulation by different lipid phases of synaptic vesicle membrane Wang, C.; Tu, J.; Zhang, S.; Cai, B.; Liu, Z.; Hou, S.; Liu, Z.; Diao, J.; Zhu, Z.-J.; Liu, C.; Li, D. 10.1101/587766 — biophysics — Posted on 2019-03-24 858 Interleukin-1 receptor antagonist treatment in acute ischaemic stroke does not alter systemic markers of anti-microbial defence McCulloch, L.; Allan, S. M.; Smith, C. J.; McColl, B. W. 10.1101/587881 — immunology — Posted on 2019-03-24 859 A phenotypically plastic magic trait promoting reproductive isolation in sticklebacks? Garduno-Paz, M.; Huntingford, F.; Adams, C. 10.1101/587675 — evolutionary biology — Posted on 2019-03-24 860 Global mammalian zooregions reveal a signal of past human impacts Rueda, M.; Gonzalez Suarez, M.; Revilla, E. 10.1101/586313 — ecology — Posted on 2019-03-24 861 DeepTRIAGE: Interpretable and Individualised BiomarkerScores using Attention Mechanism for the Classification of Breast Cancer Sub-types Beykikhoshk, A.; Quinn, T. P.; Lee, S. C.; Tran, T.; Venkatesh, S. 10.1101/533406 — biophysics — Posted on 2019-03-24 862 Increased oral Epstein-Barr virus shedding with HIV-1 co-infection is due to a combination of B cell activation and impaired cellular immune control Byrne, C. M.; Johnson, C.; Orem, J.; Okuku, F.; Huang, M.-L.; Selke, S.; Wald, A.; Corey, L.; Schiffer, J. T.; Casper, C.; Coombs, D.; Gantt, S. 10.1101/587063 — pathology — Posted on 2019-03-24 863 Cerebral Blood Flow Increases Across Early Childhood Paniukov, D.; Lebel, R. M.; Giesbrecht, G.; Lebel, C. 10.1101/587139 — neuroscience — Posted on 2019-03-24 864 A molecular gradient along the longitudinal axis of the human hippocampus informs large-scale behavioral systems Vogel, J.; La Joie, R.; Grothe, M. J.; Diaz-Papkovich, A.; Doyle, A.; Vachon-Presseau, E.; Lepage, C.; Vos de Wael, R.; Iturria-Medina, Y.; Bernhardt, B.; Rabinovici, G. D.; Evans, A. C. 10.1101/587071 — neuroscience — Posted on 2019-03-24 865 Keep your hands apart: independent representations of ipsilateral and contralateral forelimbs in primary motor cortex Heming, E.; Cross, K.; Takei, T.; Cook, D. J.; Scott, S. H. 10.1101/587378 — neuroscience — Posted on 2019-03-24 866 Enriching hippocampal memory function in older adults through real-world exploration Kolarik, B. S.; Stark, S. M.; Rutledge, S. M.; Stark, C. E. 10.1101/586974 — neuroscience — Posted on 2019-03-24 867 Revealing virulence potential of clinical and environmental Aspergillus fumigatus isolates using Whole-genome sequencing Puertolas-Balint, F.; Rossen, J. W.; Oliveira dos Santos, C.; Chlebowicz, M. A.; Raangs, E.; van Putten, M. L.; Sola-Campoy, P. J.; Han, L.; Schmidt, M.; Garcia-Cobos, S. 10.1101/587402 — microbiology — Posted on 2019-03-24 868 Transcriptome-based prediction of complex traits in maize Azodi, C.; Pardo, J.; VanBuren, R.; de los Campos, G.; Shiu, S.-H. 10.1101/587121 — genetics — Posted on 2019-03-24 869 Population divergence time estimation using individual lineage label switching Beerli, P.; Ashki, H.; Mashayekhi, S.; Palczewski, M. 10.1101/587832 — evolutionary biology — Posted on 2019-03-24 870 Bacterial biodiversity drives the evolution of CRISPR-based phage resistance in Pseudomonas aeruginosa Alseth, E. O.; Pursey, E.; Lujan, A.; McLeod, I.; Rollie, C.; Westra, E. 10.1101/586115 — evolutionary biology — Posted on 2019-03-24 871 A Divide-and-Conquer Method for Scalable Phylogenetic Network Inference from Multi-locus Data Zhu, J.; Liu, X.; Ogilvie, H.; Nakhleh, L. 10.1101/587725 — evolutionary biology — Posted on 2019-03-24 872 Progressive recruitment of distal MEC-4 channels determines touch response strength in C. elegans Katta, S.; Sanzeni, A.; Vergassola, M.; Goodman, M. B. 10.1101/587014 — neuroscience — Posted on 2019-03-24 873 Endosymbiotic bacteria are prevalent and diverse in agricultural spiders White, J. A.; Styer, A.; Rosenwald, L. C.; Curry, M. M.; Welch, K. D.; Athey, K. J.; Chapman, E. G. 10.1101/586750 — microbiology — Posted on 2019-03-24 874 A Transcriptome Fingerprinting Assay for Clinical Immune Monitoring Altman, M. C.; Baldwin, N.; Whalen, E.; Al-Shaikhly, T.; Presnell, S.; Khaenam, P.; Gersuk, V. H.; Chiche, L.; Jourde-Chiche, N.; Phillips, T.; Klintmalm, G.; O'Garra, A.; Berry, M.; Bloom, C.; Wilkinson, R. J.; Graham, C. M.; Lipman, M.; Lertmemongkolchai, G.; Kheradmand, F.; Mejias, A.; Ramilo, O.; Palucka, K.; Pascual, V.; Banchereau, J.; Chaussabel, D. 10.1101/587295 — immunology — Posted on 2019-03-24 875 Augmentation of T-cell activation by oscillatory forces and engineered antigen-presenting cells Majedi, F. S.; Hasani-Sadrabadi, M. M.; Thauland, T. J.; Li, S.; Bouchard, L.-S.; Butte, M. 10.1101/580704 — immunology — Posted on 2019-03-24 876 Diversity and relative abundance of Collembola in a wheat (Triticum aestivum) field at Aligarh Abbas, M. J.; Parwez, H. J. 10.1101/580811 — ecology — Posted on 2019-03-24 877 Global distribution of earthworm diversity Phillips, H. R. P.; Guerra, C. A.; Bartz, M. L. C.; Briones, M. J. I.; Brown, G.; Ferlian, O.; Gongalsky, K. B.; Krebs, J.; Orgiazzi, A.; Schwarz, B.; Bachs, E. M.; Bennett, J.; Brose, U.; Decaens, T.; De Vries, F. T.; Konig-Ries, B.; Lavelle, P.; Loreau, M.; Mathieu, J.; Mulder, C.; van der Putten, W.; Ramirez, K. S.; Rillig, M. C.; Russell, D.; Rutgers, M.; Thakur, M. P.; Wall, D.; Wardle, D.; sWorm Data Providers, ; Cameron, E.; Eisenhauer, N. 10.1101/587394 — ecology — Posted on 2019-03-24 878 Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma Starrett, G. J.; Thakuria, M.; Chen, T.; Marcelus, C.; Cheng, J.; Nomburg, J.; Thorner, A. R.; Slevin, M. K.; Powers, W.; Burns, R. T.; Perry, C.; Piris, A.; Kuo, F. C.; Rabinowits, G.; Giobbie-Hurder, A.; MacConaill, L. E.; DeCaprio, J. A. 10.1101/587626 — cancer biology — Posted on 2019-03-24 879 Cell BLAST: Searching large-scale scRNA-seq database via unbiased cell embedding Cao, Z.-J.; Wei, L.; Lu, S.; Yang, D.-C.; Gao, G. 10.1101/587360 — bioinformatics — Posted on 2019-03-24 880 Self-Organizing Map Methodology for Sorting Differential Expression Data of MMP-9 Inhibition St Clair, R.; Teti, M.; Knapinska, A.; Fields, G.; Hahn, W.; Barenholtz, E. 10.1101/586628 — bioinformatics — Posted on 2019-03-24 881 Formalizing metabolic-regulatory networks by hybrid automata Liu, L.; Bockmayr, A. 10.1101/586198 — systems biology — Posted on 2019-03-24 882 Linalool acts as a fast and reversible anesthetic in Hydra Goel, T.; Wang, R.; Martin, S.; Lanphear, E.; Collins, E.-M. S. 10.1101/584946 — pharmacology and toxicology — Posted on 2019-03-24 883 Whisker map organization in somatosensory cortex of awake, behaving mice Wang, H. C.; LeMessurier, A. M.; Feldman, D. E. 10.1101/587634 — neuroscience — Posted on 2019-03-24 884 FcγRIIB I232T polymorphic change allosterically suppresses ligand binding Hu, W.; Zhang, Y.; Sun, X.; Xu, L.; Xie, H.; Li, Z.; Liu, W.; Lou, J.; Chen, W. 10.1101/586487 — immunology — Posted on 2019-03-24 885 5-HT2B serotonin receptor agonist BW723C86 shapes the macrophage gene profile via AhR and impairs monocyte-to-osteoclast differentiation Nieto, C.; Rayo, I.; de las Casas-Engel, M.; Izquierdo, E.; Alonso, B.; Vega, M. A.; Corbi, A. L. 10.1101/587709 — immunology — Posted on 2019-03-24 886 Estimating and accounting for genotyping errors in RAD-seq experiments Bresadola, L.; Link, V.; Buerkle, A.; Lexer, C.; Wegmann, D. 10.1101/587428 — evolutionary biology — Posted on 2019-03-24 887 Estimating Diversity Through Time using Molecular Phylogenies: Old and Species-Poor Frog Families are the Remnants of a Diverse Past Billaud, O.; Moen, D.; Parsons, T.; Morlon, H. 10.1101/586420 — evolutionary biology — Posted on 2019-03-24 888 Automated reconstruction of all gene histories in large bacterial pangenome datasets and search for co-evolved gene modules with Pantagruel Lassalle, F.; Didelot, X.; Jauneikaite, E.; Veber, P. 10.1101/586495 — bioinformatics — Posted on 2019-03-24 889 STATegra: a comprehensive multi-omics dataset of B-cell differentiation in mouse Gomez-Cabrero, D.; Tarazona, S.; Ferreiros-Vidal, I.; Ramirez, R. N.; Company, C.; Schmidt, A.; von Saint Paul, V.; Reijmers, T.; Marabita, F.; Rodriguez-Ubreva, J.; Garcia-Gomez, A.; Caroll, T.; Cooper, L.; Liang, Z.; Dharmalingam, G.; Balzano-Nogueira, L.; Lagani, V.; Tsamardinos, I.; Lappe, M.; Maier, D.; Westerhuis, J. A.; Thomas, T.; Imhof, A.; Ballestar, E.; Mortazavi, A.; Merkenschlager, M.; Tenger, J.; Conesa, A. 10.1101/587477 — bioinformatics — Posted on 2019-03-24 890 Genetic structure of prey populations underlies the geographic mosaic of arms race coevolution Hague, M.; Stokes, A.; Feldman, C.; Brodie, E.; Brodie, E. 10.1101/585851 — evolutionary biology — Posted on 2019-03-24 891 Genomic landscape of the global oak phylogeny Hipp, A. L.; Manos, P. S.; Hahn, M.; Avishai, M.; Bodenes, C.; Cavender-Bares, J.; Crowl, A.; Deng, M.; Denk, T.; Fitz-Gibbon, S.; Gailing, O.; Gonzalez-Elizondo, M. S.; Gonzalez-RodrIguez, A.; Grimm, G. W.; Jiang, X.; Kremer, A.; Lesur, I.; McVay, J. D.; Plomion, C.; RodrIguez-Correa, H.; Schulze, E.-D.; Simeone, M. C.; Sork, V. L.; Valencia-Avalos, S. 10.1101/587253 — evolutionary biology — Posted on 2019-03-24 892 ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatin Lin, Q. X. X.; Rebbani, K.; Jha, S.; Benoukraf, T. 10.1101/585653 — genomics — Posted on 2019-03-24 893 Real-world expectations and their affective value modulate object processing Caplette, L.; Gosselin, F.; Mermillod, M.; Wicker, B. 10.1101/408542 — neuroscience — Posted on 2019-03-24 894 Germline features associated with immune infiltration in solid tumors Shahamatdar, S.; He, M. X.; Reyna, M.; Gusev, A.; AlDubayan, S. H.; Van Allen, E. M.; Ramachandran, S. 10.1101/586081 — genetics — Posted on 2019-03-24 895 Large-scale GWAS reveals genetic architecture of brain white matter microstructure and genetic overlap with cognitive and mental health traits (n=17,706) Zhao, B.; Zhang, J.; Ibrahim, J.; Luo, T.; Santelli, R.; Li, Y.; Li, T.; Shan, Y.; Zhu, Z.; Zhou, F.; Liao, H.; Nichols, T.; Zhu, H. 10.1101/288555 — genetics — Posted on 2019-03-24 896 Desiccation-induced changes in recombination rate and crossover interference in Drosophila melanogaster: evidence for fitness-dependent plasticity Aggarwal, D. D.; Rybnikov, S. R.; Cohen, I.; Frenkel, Z.; Rashkovetsky, E.; Michalak, P.; Korol, A. B. 10.1101/382259 — genetics — Posted on 2019-03-24 897 Computational Drug Recommendation Approaches toward Safe Polypharmacy Chiang, W.-H.; Ning, X. 10.1101/518415 — bioinformatics — Posted on 2019-03-24 898 A generic multivariate framework for the integration of microbiome longitudinal studies with other data types Bodein, A.; Chapleur, O.; Droit, A.; Le Cao, K.-A. 10.1101/585802 — bioinformatics — Posted on 2019-03-24 899 Morphological variation in Blommersia pelvic shape coincides with muscular architecture and parallels genus phylogenetic evolution Santos-Santos, J. H.; Guinovart-Castan, M.; Vieites, D. 10.1101/586248 — evolutionary biology — Posted on 2019-03-24 900 Prediction of inter-residue contacts with DeepMetaPSICOV in CASP13 Kandathil, S. M.; Greener, J. G.; Jones, D. T. 10.1101/586800 — bioinformatics — Posted on 2019-03-24 901 Computational and experimental insights into the chemosensory navigation of Aedes aegypti mosquito larvae Lutz, E. K.; Grewal, T. S.; Riffell, J. A. 10.1101/585075 — animal behavior and cognition — Posted on 2019-03-24 902 On Transformative Adaptive Activation Functions in Neural Networks for Gene Expression Inference Kunc, V.; Klema, J. 10.1101/587287 — bioinformatics — Posted on 2019-03-24 903 COMICS: A pipeline for the composite identification of selection across multiple genomic scans using Invariant Coordinate Selection in R Nelson, J. T.; Cornejo, O. E. 10.1101/587469 — bioinformatics — Posted on 2019-03-24 904 MethylCal: Bayesian calibration of methylation levels Ochoa, E.; Zuber, V.; Fernandez-Jimenez, N.; Bilbao, J. R.; Clark, G. R.; Maher, E. R.; Bottolo, L. 10.1101/587519 — bioinformatics — Posted on 2019-03-24 905 Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders Mohammadi, S.; Davila-Velderrain, J.; Kellis, M. 10.1101/586859 — systems biology — Posted on 2019-03-24 906 Germline features associated with immune infiltration in solid tumors Shahamatdar, S.; He, M. X.; Reyna, M.; Gusev, A.; AlDubayan, S. H.; Van Allen, E. M.; Ramachandran, S. 10.1101/586081 — genetics — Posted on 2019-03-24 907 Quantitation of cis-translational control by general mRNA sequence features in five eukaryotes Li, J. J.; Chew, G.-L.; Biggin, M. D. 10.1101/587584 — genomics — Posted on 2019-03-24 908 Affordable Remote Monitoring of Plant Growth and Facilities using Raspberry Pi Computers Grindstaff, B.; Mabry, M. E.; Blischak, P. D.; Quinn, M.; Pires, J. C. 10.1101/586776 — bioinformatics — Posted on 2019-03-24 909 Causal Network Inference from Gene Transcriptional Time Series Response to Glucocorticoids Lu, J.; Dumitrascu, B.; McDowell, I. C.; Jo, B.; Barrera, A.; Hong, L. K.; Leichter, S.; Reddy, T. E.; Engelhardt, B. E. 10.1101/587170 — bioinformatics — Posted on 2019-03-24 910 Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP Kinases to SPEECHLESS Putarjunan, A.; Ruble, J.; Srivastava, A.; Zhao, C.; Rychel, A. L.; Hofstetter, A. K.; Tang, X.; Zhu, J.-K.; Tama, F.; Zheng, N.; Torii, K. U. 10.1101/587154 — plant biology — Posted on 2019-03-24 911 Linear Double-stranded DNAs as Innovative Biological Parts to Implement Genetic Circuits in Mammalian Cells Li, S.; Su, W.; Zhang, C. 10.1101/266056 — synthetic biology — Posted on 2019-03-24 912 Integrated Field’s metal microelectrodes based microfluidic impedance cytometry for cell-in-droplet quantification Panwar, J.; Roy, R. 10.1101/278069 — bioengineering — Posted on 2019-03-24 913 Spatial structure governs the mode of tumour evolution Noble, R.; Burri, D.; Kather, J. N.; Beerenwinkel, N. 10.1101/586735 — cancer biology — Posted on 2019-03-23 914 DNA-scaffolded biomaterials enable modular and tunable control of cell-based cancer immunotherapies Huang, X.; Williams, J. Z.; Chang, R.; Li, Z.; Gai, E.; Patterson, D. M.; Yu, W.; Lim, W. A.; Desai, T. A. 10.1101/587105 — bioengineering — Posted on 2019-03-23 915 3D microenvironment stiffness regulates tumor spheroid growth and mechanics via p21 and ROCK Taubenberger, A. V.; Girardo, S.; Traber, N.; Fischer-Friedrich, E.; Krater, M.; Wagner, K.; Kurth, T.; Richter, I.; Haller, B.; Binner, M.; Hahn, D.; Freudenberg, U.; Werner, C.; Guck, J. 10.1101/586784 — bioengineering — Posted on 2019-03-23 916 eIF5B gates the transition from translation initiation to elongation Wang, J.; Johnson, A. G.; Lapointe, C. P.; Choi, J.; Prabhakar, A.; Chen, D.-H.; Petrov, A. N.; Puglisi, J. D. 10.1101/587022 — biochemistry — Posted on 2019-03-23 917 EvolvingSTEM: A microbial evolution-in-action curriculum that enhances learning of evolutionary biology and biotechnology Cooper, V. S.; Warren, T. M.; Matela, A. M.; Handwork, M.; Scarponi, S. 10.1101/514513 — evolutionary biology — Posted on 2019-03-23 918 Direct and transgenerational effects of an experimental heat wave on early life stages in a freshwater snail Leicht, K.; Seppala, O. 10.1101/449777 — ecology — Posted on 2019-03-23 919 Lipid membranes trigger misfolding and self-assembly of amyloid β 42 protein into aggregates Banerjee, S.; Hashemi, M.; Zagorski, K.; Lyubchenko, Y. 10.1101/587493 — neuroscience — Posted on 2019-03-23 920 Human DNA-PK activates a STING-independent DNA sensing pathway Burleigh, K.; Maltbaek, J.; Cambier, S.; Green, R.; Gale, M.; James, R. C.; Stetson, D. B. 10.1101/587501 — immunology — Posted on 2019-03-23 921 IMPACT OF GENOME ARCHITECTURE UPON THE FUNCTIONAL ACTIVATION AND REPRESSION OF Hox REGULATORY LANDSCAPES Rodriguez-Carballo, E.; Lopez-Delisle, L.; Yakushiji-Kaminatsui, N.; Ullate-Agote, A.; Duboule, D. 10.1101/587303 — developmental biology — Posted on 2019-03-23 922 Constitutive expression of a fluorescent protein reports the size of live human cells Berenson, D. F.; Zatulovskiy, E.; Xie, S.; Skotheim, J. M. 10.1101/587162 — cell biology — Posted on 2019-03-23 923 Class A GPCRs use the membrane potential to increase their sensitivity and selectivity Shalaeva, D.; Cherepanov, D.; Galperin, M.; Vriend, G.; Mulkidjanian, A. 10.1101/587576 — biophysics — Posted on 2019-03-23 924 Intelligent Design of 14-3-3 Docking Proteins Utilizing Synthetic Evolution Artificial Intelligence (SYN-AI) Davis, L. K. 10.1101/587204 — synthetic biology — Posted on 2019-03-23 925 CDC6 regulates both G2/M transition and metaphase-to-anaphase transition during the first meiosis of mouse oocytes Yi, Z.; Meng, T.; Ma, X.; Li, J.; Zhang, C.; Ouyang, Y.; Heide, S.; Qiao, J.; Sun, Q.-Y.; Qian, W. 10.1101/587238 — developmental biology — Posted on 2019-03-23 926 High-throughput Multimodal Automated Phenotyping (MAP) with Application to PheWAS Liao, K. P.; Sun, J.; Cai, T. A.; Link, N.; Hong, C.; Huang, J.; Huffman, J. E.; Gronsbell, J.; Zhang, Y.; Ho, Y.-L.; Castro, V.; Gainer, V.; Murphy, S. N.; O'Donnell, C. J.; Gaziano, M. J.; Cho, K.; Szolovits, P.; Kohane, I. S.; Yu, S.; Cai, T.; VA Million Veteran Program, 10.1101/587436 — bioinformatics — Posted on 2019-03-23 927 Honey bee (Apis mellifera) larval pheromones regulate gene expression related to foraging task specialization Ma, R.; Rangel, J.; Grozinger, C. M. 10.1101/587113 — genomics — Posted on 2019-03-23 928 The polyploid genome of the mitotic parthenogenetic root knot nematode Meloidogyne enterolobii Koutsovoulos, G. D.; Poullet, M.; El Ashry, A.; Kozlowski, D. K.; Sallet, E.; Da Rocha, M.; Martin-Jimenez, C.; Perfus-Barbeoch, L.; Frey, J.-E.; Ahrens, C.; Kiewnick, S.; Danchin, E. G. 10.1101/586818 — genomics — Posted on 2019-03-23 929 Single-shot autofocus microscopy using deep learning Pinkard, H.; Phillips, Z.; Babakhani, A.; Fletcher, D. A.; Waller, L. 10.1101/587485 — bioengineering — Posted on 2019-03-23 930 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive Choudhary, S. 10.1101/578500 — bioinformatics — Posted on 2019-03-23 931 p63 cooperates with CTCF to modulate chromatin architecture in skin keratinocytes Qu, J.; Yi, G.; Zhou, H. 10.1101/525667 — genomics — Posted on 2019-03-23 932 Modulation of kinesin’s load-bearing capacity by force geometry and the microtubule track Pyrpassopoulos, S.; Shuman, H.; Ostap, E. M. 10.1101/587089 — biophysics — Posted on 2019-03-23 933 Coolpup.py - a versatile tool to perform pile-up analysis of Hi-C data Flyamer, I. M.; Illingworth, R. S.; Bickmore, W. A. 10.1101/586537 — bioinformatics — Posted on 2019-03-23 934 Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT Schlichthaerle, T.; Strauss, M. T.; Schueder, F.; Auer, A.; Nijmeijer, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Thevatasan, J. V.; Ries, J.; Ellenberg, J.; Jungmann, R. 10.1101/579961 — cell biology — Posted on 2019-03-23 935 RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression. Marshall, A.; Roes, M.; Passos, D. T.; DeWeerd, M.; Chaikovsky, A.; Sage, J.; Howlett, C.; Dick, F. A. 10.1101/564567 — cancer biology — Posted on 2019-03-23 936 Statistically consistent divide-and-conquer pipelines for phylogeny estimation using NJMerge Molloy, E. K.; Warnow, T. 10.1101/469130 — evolutionary biology — Posted on 2019-03-23 937 Strong Patterns of Intraspecific Variation and Local Adaptation in Great Basin Plants Revealed Through a Review of 75 Years of Experiments Baughman, O. W.; Agneray, A. C.; Forister, M. L.; Kilkenny, F. F.; Espeland, E. K.; Fiegener, R.; Horning, M. E.; Johnson, R. C.; Kaye, T. N.; Ott, J. E.; St Clair, J. B.; Leger, E. A. 10.1101/506089 — ecology — Posted on 2019-03-23 938 The inherent multidimensionality of temporal variability: How common and rare species shape stability patterns Arnoldi, J.-F.; Loreau, M.; Haegeman, B. 10.1101/431296 — ecology — Posted on 2019-03-23 939 Using a large-scale biodiversity monitoring dataset to test the effectiveness of protected areas at conserving North-American breeding birds Cazalis, V.; Belghali, S.; Rodrigues, A. S. L. 10.1101/433037 — ecology — Posted on 2019-03-23 940 Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells Earle, A. J.; Kirby, T. J.; Fedorchak, G. R.; Isermann, P.; Patel, J.; Iruvanti, S.; Moore, S. A.; Bonne, G.; Wallrath, L. L.; Lammerding, J. 10.1101/364778 — cell biology — Posted on 2019-03-23 941 A model of the entrance pupil of the human eye Aguirre, G. K. 10.1101/325548 — neuroscience — Posted on 2019-03-23 942 Effective clustering for Single Cell Sequencing cancer data Ciccolella, S.; Patterson, M.; Bonizzoni, P.; Della Vedova, G. 10.1101/586545 — cancer biology — Posted on 2019-03-23 943 IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress Grey, M. J.; Cloots, E.; Simpson, M. S.; LeDuc, N.; Serebrenik, Y.; De Luca, H.; De Sutter, D.; Luong, P.; Thiagarajah, J. R.; Paton, A. W.; Paton, J. C.; Seeliger, M.; Eyckerman, S.; Janssens, S.; Lencer, W. I. 10.1101/586305 — cell biology — Posted on 2019-03-23 944 How signals of calcium ions initiate the beats of cilia and flagella Tuszynski, J. A.; Sataric, M.; Nemes, T.; Sekulic, D. L. 10.1101/585034 — biophysics — Posted on 2019-03-23 945 3D association of ER, PR and Her2 at protein levels to aid sub-grouping of breast cancer patients in routine clinical practice Lv, J.; Yu, G.; Li, L.; Zhang, Y.; Zhang, W.; Lv, Y.; Zhang, J.; Tang, F. 10.1101/584599 — pathology — Posted on 2019-03-23 946 Control of the Endo-Lysosome Homeostasis by the Paracaspase MALT1 regulates Glioma Cell Survival Jacobs, K. A.; Andre-Gregoire, G.; Maghe, C.; Li, Y.; Thys, A.; Harford-Wright, E.; Trillet, K.; Douanne, T.; Frenel, J.-S.; Bidere, N.; Gavard, J. 10.1101/582221 — cell biology — Posted on 2019-03-23 947 tbiExtractor: A framework for Extracting Traumatic Brain Injury Common Data Elements from Radiology Reports Mahan, M.; Rafter, D.; Casey, H.; Engelking, M.; Abdallah, T.; Truwit, C.; Oswood, M.; Samadani, U. 10.1101/585331 — bioinformatics — Posted on 2019-03-23 948 A stochastic spatial model for heterogeneity in cancergrowth Queiroga, A. S.; de Morais, M. C. C.; Tortelli, T. C.; Chammas, R.; Ramos, A. F. 10.1101/584573 — systems biology — Posted on 2019-03-23 949 Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca2+ currents Bondarenko, O.; Corzo, G.; Santana, F. L.; del Rio-Portilla, F.; Darszon, A.; Lopez-Gonzalez, I. 10.1101/586297 — physiology — Posted on 2019-03-23 950 Integrin-dependent YAP signaling requires LAMTOR1 mediated delivery of Src to the plasma membrane Bouvard, D.; Block, M.; Brunner, M.; Ziegelmeyer, T.; Lallemand, D.; Pezet, M.; Chevalier, G.; Ronde, P.; Wehrle-Haller, B. M. 10.1101/585349 — cell biology — Posted on 2019-03-23 951 N-chlorination mediates protective and immunomodulatory effects of oxidized human plasma proteins Ulfig, A.; Schulz, A. V.; Müller, A.; Lupilov, N.; Leichert, L. I. 10.1101/584961 — biochemistry — Posted on 2019-03-23 952 Genetic analysis reveals novel roles for mei-MCM proteins during meiotic recombination in Drosophila Hatkevich, T.; Hartmann, M. A.; Kohl, K. P.; Sekelsky, J. 10.1101/467134 — genetics — Posted on 2019-03-23 953 Handling and Adequacy of Iodine at Household Level: Community Based Cross-sectional Survey in Dega Damot District, West Gojjam Zone, Amhara Regional State, Ethiopia Bitew, A. A.; Linigerew, W. M.; Mengistu, A. A.; Tessema, A. L. 10.1101/586677 — epidemiology — Posted on 2019-03-23 954 Modular tissue-specific regulation of doublesex underpins sexually dimorphic development in Drosophila Rice, G.; Barmina, O.; Luecke, D.; Hu, K.; Arbeitman, M.; Kopp, A. 10.1101/585158 — developmental biology — Posted on 2019-03-23 955 Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition Wasnick, R. M.; Korfei, M.; Piskulak, K.; Henneke, I.; Wilhelm, J.; Mahavadi, P.; von der Beck, D.; Koch, M.; Shalashova, I.; Klymenko, O.; Fink, L.; Witt, H.; Hackstein, H.; El Agha, E.; Bellusci, S.; Klepetko, W.; Koenigshoff, M.; Eickelberg, O.; Braun, T.; Seeger, W.; Ruppert, C.; Guenther, A. 10.1101/580498 — cell biology — Posted on 2019-03-23 956 Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras Xu, R.; Brawner, A.; Li, S.; Liu, J.; Kim, H.; Xue, H.; Pang, Z.; Kim, W.-Y.; Hart, R.; Liu, Y.; Jiang, P. 10.1101/462739 — neuroscience — Posted on 2019-03-23 957 Accelerated brain ageing and disability in multiple sclerosis Cole, J. H.; Raffel, J.; Friede, T.; Eshaghi, A.; Brownlee, W.; Chard, D.; De Stefano, N.; Enzinger, C.; Pirpamer, L.; Filippi, M.; Gasperini, C.; Rocca, M. A.; Rovira, A.; Ruggieri, S.; Sastre-Garriga, J.; Stromillo, M. L.; Uitdehaag, B.; Vrenken, H.; Barkhof, F.; Nicholas, R.; Ciccarelli, O. 10.1101/584888 — neuroscience — Posted on 2019-03-23 958 Serial femtosecond X-ray diffraction of HIV-1 Gag MA-IP6 microcrystals at ambient temperature Ciftci, H. I.; Sierra, R. G.; Yoon, C. H.; Su, Z.; Tateishi, H.; Koga, R.; Kotaro, K.; Yumoto, F.; Senda, T.; Liang, M.; Wakatsuki, S.; Otsuka, M.; Fujita, M.; Demirci, H. 10.1101/561100 — biophysics — Posted on 2019-03-23 959 Brucella periplasmic protein EipB is a molecular determinant of cell envelope integrity and virulence Herrou, J.; Willett, J.; Fiebig, A.; Czyz, D.; Cheng, J.; Ultee, E.; Briegel, A.; Bigelow, L.; Babnigg, G.; Kim, Y.; Crosson, S. 10.1101/551135 — microbiology — Posted on 2019-03-23 960 Characterization of coral-associated microbial aggregates (CAMAs) within tissues of the coral Acropora hyacinthus Wada, N.; Ishimochi, M.; Matsui, T.; Pollock, F. J.; Tang, S.-L.; Ainsworth, T. D.; Willis, B. L.; Mano, N.; Bourne, D. G. 10.1101/576488 — microbiology — Posted on 2019-03-23 961 Pluripotent Stem Cell-derived Cerebral Organoids Reveal Human Oligodendrogenesis with Dorsal and Ventral Origins Kim, H.; Xu, R.; Ragunathan, P.; Dunaevsky, A.; Liu, Y.; Dreyfus, C.; Jiang, P. 10.1101/460907 — developmental biology — Posted on 2019-03-23 962 Cellular correlates of cortical thinning throughout the lifespan Vidal-Pineiro, D.; Parker, N.; Shin, J.; French, L.; Jackowski, A. P.; Mowinckel, A. M.; Patel, Y.; Pausova, Z.; Salum, G.; Sorensen, O.; Walhovd, K. B.; Paus, T.; Fjell, A. M.; the AIBL, 10.1101/585786 — neuroscience — Posted on 2019-03-23 963 SPDI: Data Model for Variants and Applications at NCBI Holmes, J. B.; Moyer, E.; Phan, L.; Maglott, D.; Kattman, B. L. 10.1101/537449 — genomics — Posted on 2019-03-23 964 Genomic Prediction of Complex Disease Risk Lello, L.; Raben, T. G.; Yong, S. Y.; Tellier, L. C.; Hsu, S. D. H. 10.1101/506600 — genomics — Posted on 2019-03-23 965 Balancing selection shapes the Intracellular Pathogen Response in natural Caenorhabditis elegans populations van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G. 10.1101/579151 — genetics — Posted on 2019-03-23 966 Holobiont Evolution: Model with Vertical vs. Horizontal Microbiome Transmission Roughgarden, J. 10.1101/465310 — evolutionary biology — Posted on 2019-03-23 967 Adaptation and latitudinal gradients in species interactions: nest predation in birds Freeman, B.; Scholer, M.; Boehm, M.; Heavyside, J.; Schluter, D. 10.1101/552380 — evolutionary biology — Posted on 2019-03-23 968 Strong Patterns of Intraspecific Variation and Local Adaptation in Great Basin Plants Revealed Through a Review of 75 Years of Experiments Baughman, O. W.; Agneray, A. C.; Forister, M. L.; Kilkenny, F. F.; Espeland, E. K.; Fiegener, R.; Horning, M. E.; Johnson, R. C.; Kaye, T. N.; Ott, J. E.; St Clair, J. B.; Leger, E. A. 10.1101/506089 — ecology — Posted on 2019-03-23 969 Open channel droplet-based microfluidics Berry, S. B.; Lee, J. J.; Berthier, J.; Berthier, E.; Theberge, A. 10.1101/436675 — bioengineering — Posted on 2019-03-23 970 Coupled Reaction Networks for Noise Suppression Xiao, F.; Fang, M.; Yan, J.; Doyle, J. C. 10.1101/440453 — systems biology — Posted on 2019-03-23 971 Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse Cross, S. H.; Mckie, L.; Keighren, M.; West, K.; Thaung, C.; Davey, T.; Sanchez-Pulido, L.; Soares, D.; Jackson, I. J. 10.1101/513846 — molecular biology — Posted on 2019-03-23 972 Assays for monitoring Toxoplasma gondii infectivity in the laboratory mouse Wang, Q.; David Sibley, L. 10.1101/584474 — microbiology — Posted on 2019-03-23 973 Desiccation-induced changes in recombination rate and crossover interference in Drosophila melanogaster: evidence for fitness-dependent plasticity Aggarwal, D. D.; Rybnikov, S. R.; Cohen, I.; Frenkel, Z.; Rashkovetsky, E.; Michalak, P.; Korol, A. B. 10.1101/382259 — genetics — Posted on 2019-03-23 974 Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four healthcare systems Zheutlin, A. B.; Dennis, J.; Karlsson Linner, R.; Moscati, A.; Restrepo, N.; Straub, P.; Ruderfer, D.; Castro, V. M.; Chen, C.-Y.; Ge, T.; Huckins, L. M.; Charney, A.; Kirchner, H. L.; Stahl, E. A.; Chabris, C. F.; Davis, L. K.; Smoller, J. W. 10.1101/421164 — genetics — Posted on 2019-03-23 975 Sex allocation conflict and sexual selection throughout the lifespan of eusocial colonies Avila, P.; Fromhage, L.; Lehmann, L. 10.1101/454512 — evolutionary biology — Posted on 2019-03-23 976 Using a large-scale biodiversity monitoring dataset to test the effectiveness of protected areas at conserving North-American breeding birds Cazalis, V.; Belghali, S.; Rodrigues, A. S. L. 10.1101/433037 — ecology — Posted on 2019-03-23 977 Musashi binding elements in Zika and related Flavivirus 3’UTRs: A comparative study in silico de Bernardi Schneider, A.; Wolfinger, M. T. 10.1101/407833 — bioinformatics — Posted on 2019-03-23 978 A model of the entrance pupil of the human eye Aguirre, G. K. 10.1101/325548 — neuroscience — Posted on 2019-03-23 979 Using X-ray microtomography to uncover the visual world of ancient and historical insects Taylor, G. J.; Hall, S. A.; Gren, J. A.; Baird, E. 10.1101/290841 — evolutionary biology — Posted on 2019-03-23 980 Persistence of cooperation in diffusive public goods games Gerlee, P.; Altrock, P. M. 10.1101/352492 — ecology — Posted on 2019-03-23 981 Learning mutational graphs of individual tumour evolution from single-cell and multi-region sequencing data Ramazzotti, D.; Graudenzi, A.; De Sano, L.; Antoniotti, M.; Caravagna, G. 10.1101/132183 — bioinformatics — Posted on 2019-03-23 982 MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions Piccolo, F.; Liu, Z.; Dong, P.; Hsu, C.-L.; Stoyanova, E. I.; Rao, A.; Tjian, R.; Heintz, N. 10.1101/586867 — molecular biology — Posted on 2019-03-23 983 Modulation of kinesin’s load-bearing capacity by force geometry and the microtubule track Pyrpassopoulos, S.; Shuman, H.; Ostap, E. M. 10.1101/587089 — biophysics — Posted on 2019-03-23 984 A newly defined cullin-RING ubiquitin ligase promotes thermotolerance as part of the Intracellular Pathogen Response in C. elegans Panek, J.; Reddy, K. C.; Luallen, R. J.; Fulzele, A.; Bennett, E. J.; Troemel, E. R. 10.1101/586834 — biochemistry — Posted on 2019-03-23 985 Nanodiamonds enable adaptive-optics enhanced, super-resolution, two-photon excitation microscopy Patton, B. R.; Johnstone, G. E.; Cairns, G. S. 10.1101/586743 — bioengineering — Posted on 2019-03-22 986 Comparing quality of reporting between preprints and peer-reviewed articles in the biomedical literature Carneiro, C. F. D.; Queiroz, V. G. S.; Moulin, T. C.; Carvalho, C. A. M.; Haas, C. B.; Rayee, D.; Henshall, D. E.; De-Souza, E. A.; Espinelli, F.; Boos, F. Z.; Guercio, G. D.; Costa, I. R.; Hajdu, K. L.; Modrak, M.; Tan, P. B.; Burgess, S. J.; Guerra, S. F. S.; Bortoluzzi, V. T.; Amaral, O. B. 10.1101/581892 — scientific communication and education — Posted on 2019-03-22 987 Anchoring of actin to the plasma membrane enables tension production in the fission yeast cytokinetic ring Wang, S.; O'Shaughnessy, B. 10.1101/586792 — cell biology — Posted on 2019-03-22 988 The ability of single genes vs full genomes to resolve time and space in outbreak analysis Dudas, G.; Bedford, T. 10.1101/582957 — epidemiology — Posted on 2019-03-22 989 Lifetime changes in CD4 count, viral load suppression and adherence among adolescents living with HIV in urban Peru Rodriguez, C.; Kolevic, L.; Ramos, A.; Wong, M.; Munoz, M.; Patel, K.; Franke, M. F. 10.1101/580084 — epidemiology — Posted on 2019-03-22 990 Patterns and predictors of Staphylococcus aureus carriage during the first year of life; a longitudinal study Regev-Yochay, G.; Reiss-Mandel, A.; Rubin, C.; Maayan-Metzger, A.; Novikov, I.; Jaber, H.; Dolitzky, M.; Freedman, L.; Rahav, G. 10.1101/586032 — epidemiology — Posted on 2019-03-22 991 Multiple-serotype models of dengue virus transmission: simulation study and perspectives for the application of inference in epidemiological surveillance Souto-Maior, C. 10.1101/583351 — epidemiology — Posted on 2019-03-22 992 Gestational diabetes using diverse diagnostic criteria, risk factors including dietary intakes, pregnancy outcomes and postpartum glycemic status: a nested case-control study in Ghana Agbozo, F.; Abubakari, A.; Zotor, F.; Jahn, A. 10.1101/582239 — epidemiology — Posted on 2019-03-22 993 A multidimensional functional fitness score is a stronger predictor of type 2 diabetes than obesity parameters in cross sectional data. Patil, P.; Lalwani, P.; Vidwans, H. B.; Kulkarni, S. A.; Bais, D.; Diwekar-Joshi, M. M.; Rasal, M.; Bhasme, N.; Naik, M.; Batwal, S.; Watve, M. 10.1101/580860 — epidemiology — Posted on 2019-03-22 994 Landscape epidemiology of ash dieback Grosdidier, M.; Scordia, T.; Ioos, R.; Marcais, B. 10.1101/582080 — epidemiology — Posted on 2019-03-22 995 Understanding the population structure of the GHQ-12: evidence for multidimensionality using Bayesian and Exploratory Structural Equation Modelling from a large-scale UK population survey. Griffith, G.; Jones, K. 10.1101/584169 — epidemiology — Posted on 2019-03-22 996 The genome of the blind soil-dwelling and ancestrally wingless dipluran Campodea augens, a key reference hexapod for studying the emergence of insect innovations Manni, M.; Simao, F. A.; Robertson, H. M.; Gabaglio, M. A.; Waterhouse, R. M.; Misof, B.; Niehuis, O.; Szucsich, N.; Zdobnov, E. M. 10.1101/585695 — genomics — Posted on 2019-03-22 997 TM3’seq: a tagmentation-mediated 3’ sequencing approach for improving scalability of RNA-seq experiments Pallares, L. F.; Picard, S.; Ayroles, J. F. 10.1101/585810 — genomics — Posted on 2019-03-22 998 Population genomics data supports introgression between Western Iberian Squalius freshwater fish species from different drainages Mendes, S.; Coelho, M. M.; Sousa, V. C. 10.1101/585687 — evolutionary biology — Posted on 2019-03-22 999 OMGS: Optical Map-based Genome Scaffolding Pan, W.; Jiang, T.; Lonardi, S. 10.1101/585794 — bioinformatics — Posted on 2019-03-22 1000 Effect of motor learning on prosthetic finger controlwith an intuitive myoelectric decoder Krasoulis, A.; Vijayakumar, S.; Nazarpour, K. 10.1101/585703 — bioengineering — Posted on 2019-03-22 1001 Measures of states of consciousness during attentional and cognitive load Sevenius Nilsen, A.; Juel, B. E.; Storm, J. F. 10.1101/586149 — neuroscience — Posted on 2019-03-22 1002 Error, noise and bias in de novo transcriptome assemblies Freedman, A. H.; Clamp, M.; Sackton, T. B. 10.1101/585745 — bioinformatics — Posted on 2019-03-22 1003 Coolpup.py - a versatile tool to perform pile-up analysis of Hi-C data Flyamer, I. M.; Illingworth, R. S.; Bickmore, W. A. 10.1101/586537 — bioinformatics — Posted on 2019-03-22 1004 Cellular correlates of cortical thinning throughout the lifespan Vidal-Pineiro, D.; Parker, N.; Shin, J.; French, L.; Jackowski, A. P.; Mowinckel, A. M.; Patel, Y.; Pausova, Z.; Salum, G.; Sorensen, O.; Walhovd, K. B.; Paus, T.; Fjell, A. M.; the Australian Imaging Biomarkers & Lifestyle flag, 10.1101/585786 — neuroscience — Posted on 2019-03-22 1005 Enhanced 4Pi single-molecule localization microscopy with coherent pupil based localization and light sheet illumination Liu, S.; Huang, F. 10.1101/586404 — biophysics — Posted on 2019-03-22 1006 Dietary polyunsaturated fatty acid supply improves Daphnia performance during vertical migration Isanta Navarro, J.; Fromherz, M.; Dietz, M.; Zeis, B.; Schwarzenberger, A.; Martin-Creuzburg, D. 10.1101/586156 — physiology — Posted on 2019-03-22 1007 Whole-genome and RNA sequencing reveal variation and transcriptomic coordination in the developing human prefrontal cortex Werling, D.; Pochareddy, S.; Choi, J.; An, J. Y.; Sheppard, B.; Peng, M.; Li, Z.; Dastmalchi, C.; Santperebaro, G.; Sousa, A.; Tebbenkamp, A.; Kaur, N.; Gulden, F.; Breen, M.; Liang, L.; Gilson, M.; Zhao, X.; Dong, S.; Klei, L.; Cicek, A. E.; Buxbaum, J.; Adle-Biassette, H.; Thomas, J.-L.; Aldinger, K. A.; O'Day, D. R.; Glass, I.; Zaitlen, N.; Talkowski, M.; Roeder, K.; State, M. W.; Devlin, B.; Sanders, S.; Sestan, N. 10.1101/585430 — neuroscience — Posted on 2019-03-22 1008 Cryo-EM Map of the CFA/I Pilus Rod Zheng, W.; Andersson, M.; Mortezaei, N.; Bullitt, E.; Egelman, E. H. 10.1101/586412 — molecular biology — Posted on 2019-03-22 1009 The NEDD8 cycle controlled by NEDP1 upon DNA damage is a regulatory module of the HSP70 ATPase activity Bailly, A.; Perrin, A.; Serrano-Macia, M.; Maghames, C.; Leidecker, O.; Trauchessec, H.; Martinez-Chantar, M.; Gartner, A.; Xirodimas, D. 10.1101/583864 — molecular biology — Posted on 2019-03-22 1010 Circular RNA profiling in the oocyte and cumulus cells reveals that circARMC4 is essential for porcine oocyte maturation Cao, Z.; Gao, D.; Xu, T.; Zhang, L.; Tong, X.; Zhang, D.; Wang, Y.; Ning, W.; Qi, X.; Ma, Y.; Ji, K.; Yu, T.; Li, Y.; Zhang, Y. 10.1101/586024 — developmental biology — Posted on 2019-03-22 1011 FSHR-1/GPCR activates the mitochondrial unfolded protein response in Caenorhabditis elegans Kim, S.; Sieburth, D. 10.1101/586883 — cell biology — Posted on 2019-03-22 1012 Structure-guided enhancement of selectivity of chemical probe inhibitors targeting bacterial seryl-tRNA synthetase Cain, R.; Salimaraj, R.; Punekar, A. S.; Bellini, D.; Fishwisk, C. W. G.; Czapleski, L.; Scott, D. J.; Harris, G.; Dowson, C. G.; Lloyd, A. J.; Roper, D. I. 10.1101/586255 — biochemistry — Posted on 2019-03-22 1013 Neurodegeneration caused by LRRK2-G2019S requires Rab10 in select dopaminergic neurons Petridi, S.; Middleton, C. A.; Fellgett, A.; Covill, L.; Stewart, A.; Munns, J.; Kohrs, F. E.; Hiesinger, P. R.; Wilson, L.; Chawla, S.; Elliott, C. 10.1101/586073 — neuroscience — Posted on 2019-03-22 1014 The shift to life on land selected for planning Mugan, U.; MacIver, M. A. 10.1101/585760 — neuroscience — Posted on 2019-03-22 1015 The genomic diversification of clonally propagated grapevines Vondras, A.; Minio, A.; Blanco-Ulate, B.; Figueroa, R.; Penn, M.; Zhou, Y.; Seymour, D.; Zhou, Y.; Liang, D.; Espinoza, L.; Anderson, M.; Walker, M. A.; Gaut, B.; Cantu, D. 10.1101/585869 — genomics — Posted on 2019-03-22 1016 Transcriptomics supports that pleuropodia of insect embryos function in degradation of the serosal cuticle to enable hatching Konopova, B.; Buchberger, E.; Crisp, A. 10.1101/584029 — developmental biology — Posted on 2019-03-22 1017 Grant Reviewer Perceptions of Panel Discussion in Face-to-Face and Virtual Formats: Lessons from Team Science? Gallo, S. A.; Schmaling, K.; Thompson, L. A.; Glisson, S. 10.1101/586685 — scientific communication and education — Posted on 2019-03-22 1018 Deliver on Your Own: Disrespectful Maternity Care in rural Kenya Lusambili, A. M.; Naanyu, V. N.; Wade, T. J.; Mossman, L.; Pell, R.; Mulama, K.; Nyaga, L.; Obure, J.; Mantel, M.; Ngetich, A.; Temmerman, M. 10.1101/586693 — scientific communication and education — Posted on 2019-03-22 1019 Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna Motiei, A.; Brindefalk, B.; Ogonowski, M.; El-Shehawy, R.; Pastuszek, P.; Ek, K.; Liewenborg, B.; Udekwu, K.; Gorokhova, E. 10.1101/586669 — pharmacology and toxicology — Posted on 2019-03-22 1020 A salt-induced kinase (SIK) is required for the metabolic regulation of sleep Grubbs, J. J.; Lopes, L. E.; van der Linden, A. M.; Raizen, D. M. 10.1101/586701 — neuroscience — Posted on 2019-03-22 1021 ERK1/2 signalling dynamics promote neural differentiation by regulating the polycomb repressive complex Semprich, C. I.; Metzis, V.; Patel, H.; Briscoe, J.; Storey, K. G. 10.1101/586719 — developmental biology — Posted on 2019-03-22 1022 Genetic admixture patterns in Argentinian Patagonia Parolin, M. L.; Toscanini, U. F.; Velazquez, I. F.; Llull, C.; Berardi, G. L.; Holley, A.; Tamburrini, C.; Avena, S.; Carnese, F. R.; Lanata, J. L.; Sanchez Carnero, N.; Arce, L. F.; Basso, N. G.; Pereira, R.; Gusmao, L. 10.1101/586610 — genetics — Posted on 2019-03-22 1023 Genetic and antigenic variation of foot-and-mouth disease virus during persistent infection in naturally infected cattle and Asian buffalo in India Biswal, J. K.; Ranjan, R.; Subramaniam, S.; Mohapatra, J. K.; Patidar, S.; Sharma, M. K.; Bertram, M. R.; Brito, B.; Rodriguez, L. L.; Pattnaik, B.; Arzt, J. 10.1101/586644 — evolutionary biology — Posted on 2019-03-22 1024 Levels of knowledge and attitude on preconception care at public hospitals in Wolayita Zone, South Ethiopia kassa, z. y.; Tenaw, Z.; Astatkie, A.; Siyoum, M.; Bekele, G.; Taye, K.; Mekonnen, S.; Kassaye, Z. 10.1101/586636 — epidemiology — Posted on 2019-03-22 1025 Numerical simulation for behind armor blunt trauma of human torso under non-penetrating ballistic impact Tang, F.; Guo, Z.; Yuan, M.; Qian, X.; Du, Z. 10.1101/586594 — bioengineering — Posted on 2019-03-22 1026 Effects of short-term resistance training and tapering on maximal strength, peak power, throwing ball velocity, and sprint performance in handball players Hermassi, S.; Ghaith, A.; Schwesig, R.; Shephard, R. J.; Souhaiel Chelly, M. 10.1101/586586 — developmental biology — Posted on 2019-03-22 1027 Tamoxifen Suppresses Pancreatic β-Cell Proliferation in Mice Ahn, S.-H.; Granger, A.; Rankin, M. M.; Lam, C. J.; Cox, A. R.; Kushner, J. A. 10.1101/586602 — developmental biology — Posted on 2019-03-22 1028 Stratification and prediction of drug synergy based on target functional similarity Yang, M.; Menden, M. P.; Jaaks, P.; Dry, J.; Garnett, M.; Saez-Rodriguez, J. 10.1101/586123 — bioinformatics — Posted on 2019-03-22 1029 A multi-omics digital research object for the genetics of sleep regulation. Jan, M.; Gobet, N.; Diessler, S.; Franken, P.; Xenarios, I. 10.1101/586206 — bioinformatics — Posted on 2019-03-22 1030 Systematic Comparison of High-throughput Single-Cell and Single-Nucleus Transcriptomes during Cardiomyocyte Differentiation Selewa, A.; Dohn, R.; Eckart, H.; Lozano, S.; Xie, B.; Gauchat, E.; Elorbany, R.; Rhodes, K.; Burnett, J.; Gilad, Y.; Pott, S.; Basu, A. 10.1101/585901 — genomics — Posted on 2019-03-22 1031 Selection on VPS13A linked to long-distance migratory behavior in a songbird Toews, D. P. L.; Taylor, S. A.; Streby, H. M.; Kramer, G. R.; Lovette, I. J. 10.1101/585398 — evolutionary biology — Posted on 2019-03-22 1032 Optimal Individualized Combination Immunotherapy/Oncolytic Virotherapy Determined Through In Silico Clinical Trials Improves Late Stage Melanoma Patient Outcomes Cassidy, T.; Craig, M. 10.1101/585711 — cancer biology — Posted on 2019-03-22 1033 Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodelling Katris, N. J.; Amiar, S.; Berry, L.; Dass, S.; Shears, M. J.; Brunet, C.; Touquet, B.; Hakimi, M.-A.; McFadden, G. I.; Yamaryo-Botte, Y.; Botte, C. Y. 10.1101/585737 — microbiology — Posted on 2019-03-22 1034 PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism Jain, S. U.; Do, T. J.; Lund, P. J.; Rashoff, A. Q.; Cieslik, M.; Diehl, K. L.; Bajic, A.; Juretic, N.; Deshmukh, S.; Venneti, S.; Muir, T. W.; Garcia, B. A.; Jabado, N.; Lewis, P. W. 10.1101/585729 — cancer biology — Posted on 2019-03-22 1035 Characterization of genes and alleles involved in the control of flowering time in grapevine Kamal, N.; Ochssner, I.; Schwandner, A.; Viehöver, P.; Hausmann, L.; Töpfer, R.; Weisshaar, B.; Holtgräwe, D. L. 10.1101/584268 — genetics — Posted on 2019-03-22 1036 Syncrip/hnRNPQ is required for activity-induced Msp300/Nesprin-1 expression and new synapse formation Titlow, J.; Robertson, F.; Jarvelin, A.; Ish-Horowicz, D.; Smith, C.; Gratton, E.; Davis, I. 10.1101/585679 — neuroscience — Posted on 2019-03-22 1037 Indirect Readout of DNA Controls Filamentation and Activation of a Sequence-Specific Endonuclease Polley, S.; Lyumkis, D.; Horton, N. C. 10.1101/585943 — biochemistry — Posted on 2019-03-22 1038 Evaluation of BMP-mediated patterning in zebrafish embryos using a growing finite difference embryo model Li, L. M.; Wang, X. M.; Mullins, M. C.; Umulis, D. M. 10.1101/585471 — systems biology — Posted on 2019-03-22 1039 3.1A structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids Lahiri, I.; Xu, J.; Han, B. G.; Oh, J.; Wang, D.; DiMaio, F.; Leschziner, A. E. 10.1101/585547 — molecular biology — Posted on 2019-03-22 1040 An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion Sathyan, K. M.; McKenna, B. D.; Anderson, W.; Duarte, F. M.; Core, L. J.; Guertin, M. J. 10.1101/585927 — molecular biology — Posted on 2019-03-22 1041 The influence of image masking on object representations during rapid serial visual presentation Robinson, A. K.; Grootswagers, T.; Carlson, T. A. 10.1101/515619 — neuroscience — Posted on 2019-03-21 1042 eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models Candia, J.; Tsang, J. S. 10.1101/305870 — systems biology — Posted on 2019-03-21 1043 BrainNet: A Multi-Person Brain-to-Brain Interface for Direct Collaboration Between Brains Jiang, L. P.; Stocco, A.; Losey, D. M.; Abernethy, J. A.; Prat, C.; Rao, R. P. N. 10.1101/425066 — bioengineering — Posted on 2019-03-21 1044 Uncovering the gene machinery of the Amazon River microbiome to degrade rainforest organic matter Santos-Junior, C. D.; Sarmento, H.; Miranda, F. P. d.; Henrique-Silva, F.; Logares, R. 10.1101/585562 — biochemistry — Posted on 2019-03-21 1045 The GABA-Glutamate supramammillary-dorsal Dentate Gyrus pathway controls theta and gamma oscillations in the DG during paradoxical sleep Billwiller, F.; Castillo, L.; Elseedy, H.; Ivanov, A. I.; Scapula, J.; Ghestem, A.; Carponcy, J.; Libourel, P. A.; Bras, H.; Abdelmeguid, N. E.; Krook-Magnuson, E.; Soltesz, I.; Bernard, C.; Luppi, P.-H.; Esclapez, M. 10.1101/584862 — neuroscience — Posted on 2019-03-21 1046 Beta secretase 1-dependent amyloid precursor protein processing promotes excessive vascular sprouting through NOTCH3 signaling Durrant, C. S.; Ruscher, K.; Sheppard, O.; Coleman, M. P.; Özen, I. 10.1101/585489 — neuroscience — Posted on 2019-03-21 1047 An image-computable model for the stimulus selectivity of gamma oscillations Hermes, D.; Petridou, N.; Kay, K.; Winawer, J. 10.1101/583567 — neuroscience — Posted on 2019-03-21 1048 Hierarchical temporal prediction captures motion processing from retina to higher visual cortex Singer, Y.; Willmore, B. D.; King, A. J.; Harper, N. S. 10.1101/575464 — neuroscience — Posted on 2019-03-21 1049 The rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study Smid, J.; Althaus, C. L.; Low, N.; Unemo, M.; Herrmann, B. 10.1101/572107 — epidemiology — Posted on 2019-03-21 1050 A lipid-free and insulin-supplemented medium supports de novo fatty acid synthesis gene activation in melanoma cells Wu, S.; Naar, A. M. 10.1101/479964 — cancer biology — Posted on 2019-03-21 1051 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J. 10.1101/577585 — plant biology — Posted on 2019-03-21 1052 Accelerated brain ageing and disability in multiple sclerosis Cole, J. H.; Raffel, J.; Friede, T.; Eshaghi, A.; Brownlee, W.; Chard, D.; De Stefano, N.; Enzinger, C.; Pirpamer, L.; Filippi, M.; Gasperini, C.; Rocca, M. A.; Rovira, A.; Ruggieri, S.; Sastre-Garriga, J.; Stromillo, M. L.; Uitdehaag, B.; Vrenken, H.; Barkhof, F.; Ciccarelli, O.; Nicholas, R. 10.1101/584888 — neuroscience — Posted on 2019-03-21 1053 Developing a routine lab test for absolute quantification of Her2 in Formalin Fixed Paraffin Embedded (FFPE) breast cancer tissues using Quantitative Dot Blot (QDB) method Yu, G.; Zhang, W.; Zhang, Y.; Lv, J.; Zhang, J.; Tang, F. 10.1101/584615 — pathology — Posted on 2019-03-21 1054 Modeling mechanisms of tremor reduction for essential tremor using symmetric biphasic DBS Lee, S.; Asaad, W. F.; Jones, S. 10.1101/585117 — neuroscience — Posted on 2019-03-21 1055 Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients Ravi, A.; Halstead, F.; Bamford, A.; Casey, A.; Thomson, N.; van Schaik, W.; Snelson, C.; Goulden, R.; Foster-Nyarko, E.; Savva, G.; Whitehouse, T.; PALLEN, M.; Oppenheim, B. 10.1101/582494 — microbiology — Posted on 2019-03-21 1056 Adaptation to seasonal reproduction and thermal minima-related factors drives fine-scale divergence despite gene flow in Atlantic herring populations Fuentes-Pardo, A. P.; Bourne, C.; Singh, R.; Emond, K.; Pinkham, L.; McDermid, J. L.; Andersson, L.; Ruzzante, D. E. 10.1101/578484 — genomics — Posted on 2019-03-21 1057 Local climate and social inequality drive spatio-temporal variation in malaria risk across a complex urban landscape Santos-Vega, M.; Lowe, R.; Anselin, L.; Desai, V.; Vaishnav, K. G.; Naik, A.; Pascual, M. 10.1101/583880 — ecology — Posted on 2019-03-21 1058 The yeast proteases Ddi1 and Wss1 are both involved in the DNA replication stress response. Svoboda, M.; Konvalinka, J.; Trempe, J.-F.; Grantz Saskova, K. 10.1101/584508 — molecular biology — Posted on 2019-03-21 1059 Gut-innervating nociceptor neurons protect against enteric infection by modulating the microbiota and Peyer’s patch microfold cells Lai, N. Y.; Musser, M. A.; Pinho-Ribeiro, F. A.; Baral, P.; Ma, P.; Potts, D. E.; Chen, Z.; Paik, D.; Soualhi, S.; Shi, H.; Misra, A.; Goldstein, K.; Sivanathan, K. N.; Jacobson, A.; Wallrapp, A.; Lagomarsino, V.; Kuchroo, V. K.; Nowarski, R.; Starnbach, M. N.; Surana, N. K.; An, D.; Wu, C.; Huh, J. R.; Rao, M.; Chiu, I. M. 10.1101/580555 — immunology — Posted on 2019-03-21 1060 Functional diversification enabled grassy biomes to fill global climate space Lehmann, C.; Griffith, D.; Simpson, K.; Anderson, M.; Archibald, S.; Beerling, D.; Bond, W.; Denton, E.; Edwards, E.; Forrestel, E.; Fox, D.; Georges, D.; Hoffmann, W.; Kluyver, T.; Mucina, L.; Pau, S.; Ratnam, J.; Salamin, N.; Santini, B.; Smith, M.; Spriggs, E.; Westley, R.; Still, C.; Stromberg, C.; Osborne, C. 10.1101/583625 — ecology — Posted on 2019-03-21 1061 Human Hepatocyte Nuclear Factor 4-α encodes isoforms with distinct transcriptional functions Lambert, E.; Babeu, J.-P.; Simoneau, J.; Levesque, D.; Jolibois, E.; Scott, M. S.; Boudreau, F.; Boisvert, F.-M. 10.1101/585604 — cell biology — Posted on 2019-03-21 1062 Voice patterns in schizophrenia: A systematic review and Bayesian meta-analysis Parola, A.; Simonsen, A.; Bliksted, V.; Fusaroli, R. 10.1101/583815 — bioinformatics — Posted on 2019-03-21 1063 Effects of healthy ageing on activation pattern within the brain during movement and motor imagery: an fMRI study. Budhdeo, S.; Baron, J.-C.; Sharma, N. 10.1101/584813 — neuroscience — Posted on 2019-03-21 1064 Impairment but not abolishment of express saccades after unilateral- or bilateral cryogenic FEF inactivation Dash, S.; Peel, T. R.; Lomber, S.; Corneil, B. D. 10.1101/583823 — neuroscience — Posted on 2019-03-21 1065 Levels of sdRNAs in cytoplasm and their association with ribosomes are dependent upon stress conditions but independent from snoRNA expression Mleczko, A.; Machtel, P. J.; Walkowiak, M.; Wasilewska, A.; Bakowska-Zywicka, K. 10.1101/584367 — molecular biology — Posted on 2019-03-21 1066 Genetic architecture constrains exploitation of siderophore cooperation in Burkholderia cenocepacia Sathe, S.; Mathew, A.; Agnoli, K.; Eberl, L.; Kummerli, R. 10.1101/583898 — evolutionary biology — Posted on 2019-03-21 1067 Combined morphological and transcriptomic analyses reveal genetic regulation underlying the species-specific bulbil outgrowth in Dioscorea alata L Wu, Z.-G.; Jiang, W.; Tao, Z.-M.; Guo, X.-Z.; Pan, X.-J.; Yu, W.-H. 10.1101/585364 — plant biology — Posted on 2019-03-21 1068 Multiple memory tests in midlife improve prediction of mild cognitive impairment Gustavson, D. E.; Sanderson-Cimino, M.; Elman, J. A.; Franz, C. E.; Panizzon, M. S.; Jak, A. J.; Reynolds, C. A.; Lyons, M. J.; Kremen, W. S. 10.1101/584193 — pathology — Posted on 2019-03-21 1069 Confidence reports in decision-making with multiple alternatives violate the Bayesian confidence hypothesis Li, H.-H.; Ma, W. J. 10.1101/583963 — neuroscience — Posted on 2019-03-21 1070 Developmental Recovery of Impaired Multisensory Processing in Autism and the Cost of Switching Sensory Modality Crosse, M. J.; Foxe, J. J.; Molholm, S. 10.1101/565333 — neuroscience — Posted on 2019-03-21 1071 Superlets: time-frequency super-resolution using wavelet sets Moca, V. V.; Nagy-Dabacan, A.; Barzan, H.; Muresan, R. C. 10.1101/583732 — neuroscience — Posted on 2019-03-21 1072 Identification of reduced host transcriptomic signatures for tuberculosis and digital PCR-based validation and quantification Gliddon, H. D.; Kaforou, M.; Alikian, M.; Habgood-Coote, D.; Zhou, C.; Oni, T.; Anderson, S. T.; Brent, A. J.; Crampin, A. C.; Eley, B.; Heyderman, R. S.; Kern, F.; Langford, P. R.; Ottenhoff, T. H.; French, N.; Hibberd, M. L.; Wright, V. J.; Dockrell, H. M.; Coin, L. J.; Wilkinson, R. J.; Levin, M. 10.1101/583674 — molecular biology — Posted on 2019-03-21 1073 Population history from the Neolithic to present on the Mediterranean island of Sardinia: An ancient DNA perspective Marcus, J. H.; Posth, C.; Ringbauer, H.; Lai, L.; Skeates, R.; Sidore, C.; Beckett, J.; Furtwängler, A.; Olivieri, A.; Chiang, C.; Al-Asadi, H.; Dey, K.; Joseph, T. A.; Der Sarkissian, C.; Radzeviciute, R.; Gradoli, M. G.; Haak, W.; Reich, D.; Schlessinger, D.; Cucca, F.; Krause, J.; Novembre, J. 10.1101/583104 — genetics — Posted on 2019-03-21 1074 Exploiting the unwanted: sulphate reduction enables phosphate recovery from energy-rich sludge during anaerobic digestion. Lippens, C.; De Vrieze, J. 10.1101/584904 — bioengineering — Posted on 2019-03-21 1075 Brain gene expression in a novel mouse model of postpartum mood disorder Humby, T.; Davies, W. 10.1101/555870 — neuroscience — Posted on 2019-03-21 1076 Leptin reduces pathology and increases adult neurogenesis in a transgenic mouse model of Alzheimer’s disease Calio, M. L.; Salles, G. N.; Marinho, D. S.; Mosini, A. C. F.; Massinhani, F. H.; Ko, G. M.; Porcionatto, M. A. 10.1101/567636 — neuroscience — Posted on 2019-03-21 1077 BDNF controls bidirectional endocannabinoid-plasticity at corticostriatal synapses Gangarossa, G.; Perez, S.; Dembitskaya, Y.; Prokin, I.; Berry, H.; Venance, L. 10.1101/550947 — neuroscience — Posted on 2019-03-21 1078 A Long Timescale Stimulus History Effect in the Primary Visual Cortex Kim, H.; Homann, J.; Tank, D. W.; Berry, M. J. 10.1101/585539 — neuroscience — Posted on 2019-03-21 1079 Relationship between cardiac cycle and the timing of actions during action execution and observation Palser, E. R.; Glass, J.; Fotopoulou, A.; Kilner, J. M. 10.1101/585414 — neuroscience — Posted on 2019-03-21 1080 The role of feature-based attention in visual serial dependence Fritsche, M.; de Lange, F. P. 10.1101/584789 — neuroscience — Posted on 2019-03-21 1081 The non-dominant AAA+ ring in the ClpAP protease functions as an anti-stalling motor to accelerate protein unfolding and translocation Kotamarthi, H. C.; Sauer, R. T.; Baker, T. 10.1101/585554 — biophysics — Posted on 2019-03-21 1082 A catalog of CasX genome editing sites in common model organisms Roberson, E. D. O. 10.1101/585521 — bioinformatics — Posted on 2019-03-21 1083 Uncovering the gene machinery of the Amazon River microbiome to degrade rainforest organic matter Santos-Junior, C. D.; Sarmento, H.; Miranda, F. P. d.; Henrique-Silva, F.; Logares, R. 10.1101/585562 — biochemistry — Posted on 2019-03-21 1084 Gastrocnemius muscle remodeling explains functional deficits three months following Achilles tendon rupture Hullfish, T. J.; O'Connor, K. M.; Baxter, J. R. 10.1101/585505 — physiology — Posted on 2019-03-21 1085 Neuronal network dysfunction in a human model for Kleefstra syndrome mediated by enhanced NMDAR signaling Frega, M.; Linda, K.; Keller, J. M.; Gumus-Akay, G.; Mossink, B.; van Rhijn, J.-R.; Negwer, M.; Klein Gunnewiek, T.; Foreman, K.; Kompier, N.; Schoenmaker, C.; van den Akker, W.; Oudakker, A.; Zhou, H.; Kleefstra, T.; Schubert, D.; van Bokhoven, H.; Nadif Kasri, N. 10.1101/585596 — neuroscience — Posted on 2019-03-21 1086 Visual area V4 encodes history dependent attentional effort and single-trial perceptual detection Ghosh, S.; Maunsell, J. H. R. 10.1101/584409 — neuroscience — Posted on 2019-03-21 1087 Srrm234, but not canonical SR and hnRNP proteins drive inclusion of Dscam exon 9 variable exons Ustaoglu, P.; Haussmann, I.; Liao, H.; Torres-Mendez, A.; Arnold, R.; Irimia, M.; Soller, M. 10.1101/584003 — molecular biology — Posted on 2019-03-21 1088 Islet macrophages drive islet remodeling and compensatory hyperinsulinemia in the early diabetes Chittezhath, M.; Gunaseelan, D.; Zheng, X.; Hasan, R.; Tay, V. S.; Lim, S. T.; Wang, X.; Bornstein, S.; Berggren, P.-O.; Boehm, B.; Ruedl, C.; Ali, Y. 10.1101/584953 — molecular biology — Posted on 2019-03-21 1089 Novel cholinesterase paralogs of Schistosoma mansoni have perceived roles in cholinergic signaling, glucose scavenging and drug detoxification and are essential for parasite survival Tedla, B.; Sotillo, J.; Pickering, D.; Eichenberger, R.; Becker, L.; Loukas, A.; Pearson, M. S. 10.1101/583658 — molecular biology — Posted on 2019-03-21 1090 Evidence for the F200Y (TAC) mutation conferring benzimidazole resistance in a southern USA cattle population of Haemonchus placei spreading from a single emergence Chaudhry, U.; Redman, E. M.; Kaplan, R.; Yazwinski, T.; Sargison, N.; Gilleard, J. 10.1101/578922 — molecular biology — Posted on 2019-03-21 1091 Dosing Time Matters Ruben, M. D.; Smith, D. F.; FitzGerald, G. A.; Hogenesch, J. B. 10.1101/570119 — epidemiology — Posted on 2019-03-21 1092 WAT’s up!? – Organ-on-a-chip integrating human mature white adipose tissues for mechanistic research and pharmaceutical applications Rogal, J.; Binder, C.; Kromidas, E.; Probst, C.; Schneider, S.; Schenke-Layland, K.; Loskill, P. 10.1101/585141 — bioengineering — Posted on 2019-03-21 1093 Inferring the quasipotential landscape of microbial ecosystems with topological data analysis Chang, W. K.; Kelly, L. 10.1101/584201 — systems biology — Posted on 2019-03-21 1094 Intraventricular CXCL12 is neuroprotective and increases neurogenesis in a murine model of stroke zamproni, l.; Porcionatto, M. 10.1101/584565 — neuroscience — Posted on 2019-03-21 1095 Leveraging non-human primate multisensory neurons and circuits in assessing consciousness theory Noel, J.-P.; Ishizawa, Y.; Patel, S.; Eskandar, E.; Wallace, M. 10.1101/584516 — neuroscience — Posted on 2019-03-21 1096 EEG-fMRI reveals rapid representation of personal relevance of faces in social cognition and reward-related brain regions Bayer, M.; Berhe, O.; Dziobek, I.; Johnstone, T. 10.1101/585133 — neuroscience — Posted on 2019-03-21 1097 Mitigating Pandemic Risk with Influenza A Virus Field Surveillance at a Swine-Human Interface Rambo-Martin, B. L.; Keller, M. W.; Wilson, M. M.; Nolting, J. M.; Anderson, T. K.; Vincent, A. L.; Bagal, U.; Jang, Y.; Neuhaus, E. B.; Davis, C. T.; Bowman, A. S.; Wentworth, D. E.; Barnes, J. R. 10.1101/585588 — microbiology — Posted on 2019-03-21 1098 Dietary intake regulates the circulating inflammatory monocyte pool Jordan, S.; Tung, N.; Casanova-Acebes, M.; Chang, C.; Cantoni, C.; Zhang, D.; Wirtz, T. H.; Naik, S.; Rose, S. A.; Brocker, C. N.; Gainullina, A.; Maier, B. B.; LeRoith, D.; Gonzalez, F. J.; Meissner, F.; Ochando, J.; Rahman, A.; Chipuk, J. E.; Artyomov, M. N.; Frenette, P. S.; Piccio, L.; Berres, M.-L.; Gallagher, E. J.; Merad, M. 10.1101/582346 — immunology — Posted on 2019-03-21 1099 Re-evaluation of homozygous lethality for EF1A indel polymorphism in Pisaster ochraceus Wares, J. P.; Duffin, P. J. 10.1101/584235 — evolutionary biology — Posted on 2019-03-21 1100 Pathogen evolution when transmission and virulence are stochastic Aavani, P.; Rice, S. H. 10.1101/584425 — evolutionary biology — Posted on 2019-03-21 1101 Genomics of expanded avian sex chromosomes shows that certain chromosomes are predisposed towards sex-linkage in vertebrates Sigeman, H.; Ponnikas, S.; Chauhan, P.; Dierickx, E.; Brooke, M. d. L.; Hansson, B. 10.1101/585059 — evolutionary biology — Posted on 2019-03-21 1102 Adaptive introgression as a driver of local adaptation to climate in European white oaks Leroy, T.; Louvet, J.-M.; Lalanne, C.; Le Provost, G.; Labadie, K.; Aury, J.-M.; Delzon, S.; Plomion, C.; Kremer, A. 10.1101/584847 — evolutionary biology — Posted on 2019-03-21 1103 Development of senescence biomarkers in the common woodlouse Depeux, C.; Samba-Louaka, A.; Becking, T.; Braquart-Varnier, C.; Moreau, J.; Lemaitre, J.-F.; Laverre, T.; Paulhac, H.; Dechaume-Montcharmont, F.-X.; Gaillard, J.-M.; Beltran-Becg, S. 10.1101/583914 — evolutionary biology — Posted on 2019-03-21 1104 Immune and environment-driven gene expression during invasion: An eco-immunological application of RNA-Seq Selechnik, D.; Richardson, M. F.; Shine, R.; Brown, G. P.; Rollins, L. A. 10.1101/583617 — ecology — Posted on 2019-03-21 1105 Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect Johnson, K. E.; Howard, G.; Mo, W.; Strasser, M. K.; Lima, E. A. B. F.; Huang, S.; Brock, A. 10.1101/585216 — cancer biology — Posted on 2019-03-21 1106 Laser Recording of Subcellular Neuron Activities Chen, Y.-C.; Li, X.; Zhu, H.; Weng, W.-H.; Tan, X.; Chen, Q.; Wang, X.; Fan, X. 10.1101/584938 — bioengineering — Posted on 2019-03-21 1107 Biologically inspired model of associative memory storage with noisy neurons and synapses Zhang, C.; Zhang, D.; Stepanyants, A. 10.1101/583922 — neuroscience — Posted on 2019-03-21 1108 High-throughput RNA sequencing from paired lesional- and non-lesional skin reveals major alterations in the psoriasis circRNAome Moldovan, L. I.; Hansen, T. B.; Veno, M. T.; Hauge Okholm, T. L.; Levin Andersen, T.; Hager, H.; Iversen, L.; Kjems, J.; Johansen, C.; Kristensen, L. S. 10.1101/581066 — molecular biology — Posted on 2019-03-21 1109 Chimeric LuxR Transcription Factors Rewire Natural Product Regulation Mukherji, R.; Chowdhury, S.; Stallforth, P. 10.1101/584987 — microbiology — Posted on 2019-03-21 1110 Enhanced replication of mouse adenovirus type 1 following virus-induced degradation of protein kinase R (PKR) Goodman, D. E.; Pretto-Kernahan, C. D.; Krepostman, T. A.; Carnahan, K. E.; Spindler, K. R. 10.1101/584680 — microbiology — Posted on 2019-03-21 1111 Neuro-genetic plasticity of Caenorhabditis elegans behavioral thermal tolerance Stegeman, G. W.; Medina, D.; Cutter, A. D.; Ryu, W. S. 10.1101/583120 — genetics — Posted on 2019-03-21 1112 Neuronal function and dopamine signaling evolve at high temperature in Drosophila Jaksic, A. M.; Karner, J.; Nolte, V.; Hsu, S.-K.; Barghi, N.; Mallard, F. J.; Otte, K. A.; Svecnjak, L.; Senti, K. A.; Schlotterer, C. 10.1101/585422 — evolutionary biology — Posted on 2019-03-21 1113 Distinctive airway microbial ecology of smokers and asthmatics Turek, E. M.; Cox, M. J.; Hunter, M.; Hui, J.; James, P.; Willis-Owen, S. A.; Cuthbertson, L.; James, A.; Musk, A. W.; Moffatt, M. F.; Cookson, W. O. 10.1101/583559 — ecology — Posted on 2019-03-21 1114 A Truly Injectable Neural Stimulation Electrode Made From an In-Body Curing Polymer/Metal Composite Trevathan, J. K.; Baumgart, I.; Nicolai, E. N.; Gosink, B. A.; Asp, A. J.; Settell, M. L.; Polaconda, S. R.; Malerick, K.; Brodnick, S. K.; Zeng, W.; Knudsen, B. E.; McConico, A. L.; Sanger, Z.; Lee, J. H.; Aho, J. M.; Suminski, A. J.; Ross, E. K.; Lujan, J. L.; Weber, D. J.; Williams, J. C.; Franke, M.; Ludwig, K. A.; Shoffstall, A. J. 10.1101/584995 — bioengineering — Posted on 2019-03-21 1115 Population productivity of shovelnose rays: inferring the potential for recovery D'Alberto, B. M.; Carlson, J. K.; Pardo, S. A.; Simpfendorfer, C. A. 10.1101/584557 — zoology — Posted on 2019-03-21 1116 Chemical degumming increases larvae size and facilitates commercial production of Lumpfish (Cyclopterus lumpus) eggs Pooley, C. L.; Berwick, M. G.; Garcia de Leaniz, C. 10.1101/583641 — zoology — Posted on 2019-03-21 1117 Fundamental Theory of the Evolution Force (FTEF): Gene Engineering utilizing Synthetic Evolution Artificial Intelligence (SYN-AI) Davis, L. K.; Uppu, R. M. 10.1101/585042 — synthetic biology — Posted on 2019-03-21 1118 Evaluating the Role of Fish as Surrogates for Amphibians in Pesticide Ecological Risk Assessment Glaberman, S.; Kiwiet, J.; Aubee, C. 10.1101/584417 — pharmacology and toxicology — Posted on 2019-03-21 1119 Attenuation of entorhinal cortex hyperactivity reduces Aβ and tau pathology Rodriguez, G. A.; Barrett, G. M.; Duff, K. E.; Hussaini, A. 10.1101/487405 — neuroscience — Posted on 2019-03-21 1120 A distinct class of bursting neurons with strong gamma synchronization and stimulus selectivity in monkey V1 Onorato, I.; Neuenschwander, S.; Hoy, J.; Lima, B.; Rocha, K.-S.; Broggini, A. C.; Uran, C.; Spyropoulos, G.; Womelsdorf, T.; Fries, P.; Niell, C.; Singer, W.; Vinck, M. 10.1101/583955 — neuroscience — Posted on 2019-03-21 1121 microRNA mir-598-3p mediates susceptibility to stress-enhancement of remote fear memory Jones, M. E.; Sillivan, S. E.; Jamieson, S.; Rumbaugh, G.; Miller, C. A. 10.1101/584326 — neuroscience — Posted on 2019-03-21 1122 Dynamics of functional networks for syllable and word-level processing Rimmele, J. M.; Sun, Y.; Michalareas, G.; Ghitza, O.; Poeppel, D. 10.1101/584375 — neuroscience — Posted on 2019-03-21 1123 Stochastic Models of Polymerization Based Axonal Actin Transport Chakrabarty, N.; Jung, P. 10.1101/583716 — neuroscience — Posted on 2019-03-21 1124 Comparing self- and hetero-metacognition in the absence of verbal communication Vuillaume, L.; Martin, J.-R.; Sackur, J.; Cleeremans, A. 10.1101/585240 — neuroscience — Posted on 2019-03-21 1125 Metatranscriptomics as a tool to identify fungal species and subspecies in mixed communities Rossetto Marcelino, V.; Irinyi, L.; Eden, J.-S.; Meyer, W.; Holmes, E. C.; Sorrell, T. C. 10.1101/584649 — molecular biology — Posted on 2019-03-21 1126 A bacterial endosymbiont enables fungal immune evasion during fatal mucormycete infection Itabangi, H.; Sephton-Clark, P.; Zhou, X.; Insua, I.; Probert, M.; Correia, J.; Moynihan, P.; Gebremariam, T.; Gu, Y.; Lin, L.; Ibrahim, A. S.; Brown, G. D.; King, J. S.; Fernandez-Trillo, F.; Ballou, E. R.; Voelz, K. 10.1101/584607 — microbiology — Posted on 2019-03-21 1127 Shallow metagenomics with Nanopore sequencing in canine fecal microbiota improved bacterial taxonomy and identified an uncultured CrAssphage Cusco, A.; Salas, A.; Torre, C.; Francino, O. 10.1101/585067 — microbiology — Posted on 2019-03-21 1128 Assays for monitoring Toxoplasma gondii infectivity in the laboratory mouse Wang, Q.; Sibley, L. D. 10.1101/584474 — microbiology — Posted on 2019-03-21 1129 Tracking human population structure through time from whole genome sequences Wang, K.; Mathieson, I.; O'Connell, J.; Schiffels, S. 10.1101/585265 — evolutionary biology — Posted on 2019-03-21 1130 Structural color in Junonia butterflies evolves by tuning scale lamina thickness Thayer, R. C.; Allen, F. I.; Patel, N. H. 10.1101/584532 — evolutionary biology — Posted on 2019-03-21 1131 In silico design of glyco-D,L-peptide antiviral molecules. Agostini, L.; Morosetti, S. 10.1101/583765 — bioinformatics — Posted on 2019-03-21 1132 Live-cell Imaging Analysis of Antimycin-Type Depsipeptides via Bioorthogonal Stimulated Raman Scattering Microscopy Seidel, J. A.; Miao, Y.; Porterfield, W.; Cai, W.; Zhu, X.; Kim, S.-J.; Hu, F.; Bhattarai-Kline, S.; Min, W.; Zhang, W. 10.1101/583252 — bioengineering — Posted on 2019-03-21 1133 Trans-endothelial insulin transport is impaired in skeletal muscle capillaries of obese male mice. Williams, I. M.; McClatchey, P. M.; Bracy, D. P.; Bonner, J. S.; Valenzuela, F. A.; Wasserman, D. H. 10.1101/585372 — physiology — Posted on 2019-03-21 1134 Integrated Open-Source Software for Multiscale Electrophysiology Nasiotis, K.; Cousineau, M.; Tadel, F.; Peyrache, A.; Leahy, R.; Pack, C.; Baillet, S. 10.1101/584185 — neuroscience — Posted on 2019-03-21 1135 Untapped viral diversity in global soil metagenomes Graham, E. B.; Paez-Espino, D.; Brislawn, C.; Neches, R. Y.; Hofmockel, K. S.; Wu, R.; Kyrpides, N. C.; Jansson, J. K.; McDermott, J. E. 10.1101/583997 — microbiology — Posted on 2019-03-21 1136 E-ChRPs: Engineered Chromatin Remodeling Proteins for Precise Nucleosome Positioning Donovan, D. A.; Crandall, J. G.; Banks, O. G.; Jensvold, Z. D.; McKnight, L. E.; McKnight, J. N. 10.1101/480913 — genetics — Posted on 2019-03-21 1137 Graphical factorial surveys reveal the acceptability of wildlife observation at protected areas. Cerri, J.; Bertolino, S.; Martinelli, E. 10.1101/580688 — ecology — Posted on 2019-03-21 1138 CCL5 promotes breast cancer recurrence through macrophage recruitment in residual tumors Walens, A.; DiMarco, A. V.; Lupo, R.; Kroger, B. R.; Damrauer, J. S.; Alvarez, J. V. 10.1101/584979 — cancer biology — Posted on 2019-03-21 1139 Adaptive optics allows 3D STED-FCS measurements in the cytoplasm of living cells Barbotin, A.; Galiani, S.; Urbancic, I.; Eggeling, C.; Booth, M. 10.1101/584870 — biophysics — Posted on 2019-03-21 1140 Decomposing information into copying versus transformation Kolchinsky, A.; Corominas-Murtra, B. 10.1101/584771 — biophysics — Posted on 2019-03-21 1141 Representation of task episodes in human cortical networks Wen, T.; Duncan, J.; Mitchell, D. J. 10.1101/582858 — neuroscience — Posted on 2019-03-21 1142 A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral-shape to coccoids El Mortaji, L.; Marsin, S.; Rifflet, A.; Boneca, I. G.; Radicella, P.; Pehau-Arnaudet, G.; De Reuse, H. 10.1101/585380 — microbiology — Posted on 2019-03-21 1143 Mucosal microbiota and metabolome along the intestinal tracts reveals location specific relationship Yuan, C.; Graham, M.; Staley, C.; Subramanian, S. 10.1101/454496 — genomics — Posted on 2019-03-21 1144 Clinical features of bloodstream infections caused by the two dominant clones of endemic methicillin-resistant Staphylococcus aureus Dupper, A.; Sullivan, M. J.; Chacko, K. I.; Mishkin, A.; Ciferri, B.; Kumaresh, A.; Berbel Caban, A.; Oussenko, I.; Beckford, C.; Zeitouni, N. E.; Sebra, R.; Hamula, C.; Smith, M.; Kasarskis, A.; Patel, G.; McBride, R. B.; van Bakel, H.; Altman, D. R. 10.1101/501833 — epidemiology — Posted on 2019-03-21 1145 Lineage does not regulate the connectivity of projection neurons in the mouse olfactory bulb Lois, C.; Sanchez-Guardado, L. 10.1101/584805 — developmental biology — Posted on 2019-03-21 1146 Modular tissue-specific regulation of doublesex underpins sexually dimorphic development in Drosophila Rice, G.; Barmina, O.; Luecke, D.; Hu, K.; Arbeitman, M.; Kopp, A. 10.1101/585158 — developmental biology — Posted on 2019-03-21 1147 High Epha1 expression is a potential cell surface marker for embryonic neuro-mesodermal progenitors de Lemos, L.; Novoa, A.; Mallo, M. 10.1101/584524 — developmental biology — Posted on 2019-03-21 1148 N-linked glycans confer protein stability and modulate multidrug efflux pump assembly in Campylobacter jejuni Abouelhadid, S.; Raynes, J.; Bui, T. T. T.; Cuccui, J.; Wren, B. W. 10.1101/585463 — biochemistry — Posted on 2019-03-21 1149 RACK1 on and off the ribosome Johnson, A. G.; Lapointe, C. P.; Wang, J.; Corsepius, N. C.; Choi, J.; Fuchs, G.; Puglisi, J. D. 10.1101/582635 — biochemistry — Posted on 2019-03-21 1150 The C. elegans SET-2 histone methyltransferase maintains germline fate by preventing progressive transcriptomic deregulation across generations Robert, V. J.; Knutson, A. K.; Rechtsteiner, A.; Yvert, G.; Strome, S.; Palladino, F. 10.1101/583799 — genetics — Posted on 2019-03-21 1151 The Pax6 master control gene initiates spontaneous retinal development via a self-organising Turing network Grocott, T.; Lozano-Velasco, E.; Mok, G. F.; Munsterberg, A. E. 10.1101/583807 — developmental biology — Posted on 2019-03-21 1152 Opposing modulation of Cx26 gap junctions and hemichannels by CO2 Nijjar, S.; Maddison, D.; Meigh, L.; de Wolf, E.; Rodgers, T.; Cann, M. J.; Dale, N. 10.1101/584722 — cell biology — Posted on 2019-03-21 1153 A NOVEL MECHANISM FOR NF-κB-ACTIVATION VIA IκB-AGGREGATION: IMPLICATIONS FOR HEPATIC MALLORY-DENK-BODY INDUCED INFLAMMATION Liu, Y.; Trnka, M. J.; Guan, S.; Kwon, D.; Kim, D.-H.; Chen, J.-J.; Greer, P. A.; Burlingame, A. L.; Correia, M. A. 10.1101/585497 — cell biology — Posted on 2019-03-21 1154 Characterising memory loss in patients with autoimmune limbic encephalitis hippocampal lesions Lad, M.; Mullally, S. L.; Houston, A. L.; Kelly, T.; Griffiths, T. D. 10.1101/579979 — neuroscience — Posted on 2019-03-21 1155 Rhythmic chromatin interactions with lamin B1 reflect stochasticity in variable lamina-associated domains during the circadian cycle Brunet, A.; Forsberg, F.; Collas, P. 10.1101/584011 — genomics — Posted on 2019-03-21 1156 Patterns of diverse gene functions in genomic neighborhoods predict gene function and phenotype Mihelcic, M.; Smuc, T.; Supek, F. 10.1101/582577 — genomics — Posted on 2019-03-21 1157 Simulation of Red Blood Cell Migration in Small Arterioles: Effect of Cytoplasmic Viscosity Saadat, A.; Guido, C. J.; Shaqfeh, E. S. G. 10.1101/572933 — biophysics — Posted on 2019-03-21 1158 lionessR: single-sample network reconstruction in R Kuijjer, M. L.; Quackenbush, J.; Glass, K. 10.1101/582098 — bioinformatics — Posted on 2019-03-21 1159 Statistical learning shapes neural sequence representations Henin, S.; Turk-Browne, N.; Friedman, D.; Liu, A.; Dugan, P.; Flinker, A.; Doyle, W.; Devinsky, O.; Melloni, L. 10.1101/583856 — neuroscience — Posted on 2019-03-21 1160 Conduit integrity is compromised during acute lymph node expansion Martinez, V. G.; Pankova, V.; Krasny, L.; Singh, T.; White, I. J.; Benjamin, A. C.; Dertschnig, S.; Horsnell, H. L.; Kriston-Vizi, J.; Burden, J. J.; Huang, P. H.; Tape, C. J.; Acton, S. E. 10.1101/527481 — immunology — Posted on 2019-03-21 1161 Profiling Gene Specific Changes to RNA Editome in Preeclampsia Hasan, S.; Robbani, S. M.; Afroze, T.; Ahsan, G. U.; Hossain, M. M. 10.1101/584672 — genomics — Posted on 2019-03-21 1162 Improving the accuracy of single turnover active fluorometry (STAF) for the estimation of phytoplankton primary productivity (PhytoPP) Boatman, T. G.; Geider, R. J.; Oxborough, K. 10.1101/583591 — plant biology — Posted on 2019-03-21 1163 Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against autoimmune diseases Liu, R.; Chen, Y.; Wang, S.; Cui, Y.; Zhang, X.; Lei, Z.-N.; Hettinghouse, A.; Liu, J.; Fu, W.; Chen, Z.-S.; Liu, C. 10.1101/584540 — molecular biology — Posted on 2019-03-21 1164 Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies novel methylation loci Smith, A. K.; Ratanatharathorn, A.; Maihofer, A. X.; Naviaux, R. K.; Aiello, A. E.; Amstadter, A. B.; Ashley-Koch, A. E.; Baker, D. G.; Beckham, J. C.; Boks, M. P.; Bromet, E.; Dennis, M.; Galea, S.; Garrett, M. E.; Geuze, E.; Guffanti, G.; Hauser, M. A.; Katrinli, S.; Kilaru, V.; Kessler, R. C.; Kimbrel, N. A.; Koenen, K. C.; Kuan, P.-F.; Li, K.; Logue, M. W.; Lori, A.; Luft, B. J.; Miller, M. W.; Naviaux, J. C.; Nugent, N. R.; Qin, X.; Ressler, K. J.; Risbrough, V. B.; Rutten, B. P. F.; Stein, M. B.; Ursano, R. J.; Vermetten, E.; Vinkers, C. H.; Wang, L.; Youssef, N. A.; INTRuST Clinical Con 10.1101/585109 — genomics — Posted on 2019-03-21 1165 Universal surface-to-volume scaling and aspect ratio homeostasis in rod-shaped bacteria Ojkic, N.; Serbanescu, D.; Banerjee, S. 10.1101/583989 — biophysics — Posted on 2019-03-21 1166 Multiple mechanisms link prestimulus neural oscillations to sensory responses Iemi, L.; Busch, N. A.; Laudini, A.; Haegens, S.; Samaha, J.; Villringer, A.; Nikulin, V. V. 10.1101/461558 — neuroscience — Posted on 2019-03-21 1167 Seasonal and geographic variation in insecticide resistance in Aedes aegypti among four cities in southern Ecuador Ryan, S.; Mundis, S. J.; Aguirre, A.; Lippi, C. A.; Beltran, E.; Heras, F.; Sanchez, V.; Borbor-Cordova, M. J.; Sippy, R.; Stewart-Ibarra, A. M.; Neira, M. V. 10.1101/441360 — epidemiology — Posted on 2019-03-21 1168 The role of feedback from the auditory cortex in shaping responses to sounds in inferior colliculus Blackwell, J. M.; Rao, W.; De Biasi, M.; Geffen, M. N. 10.1101/584334 — neuroscience — Posted on 2019-03-21 1169 Changes in the Biodiversity Intactness Index in tropical and subtropical forest biomes, 2001-2012. De Palma, A.; Hoskins, A.; Gonzalez, R. E.; Newbold, T.; Sanchez-Ortiz, K.; Ferrier, S.; Purvis, A. 10.1101/311688 — ecology — Posted on 2019-03-21 1170 Molecular mechanisms of Evening Complex activity in Arabidopsis Silva, C.; Nayak, A.; Lai, X.; Hugouvieux, V.; Jung, J.-h.; Jourdain, A.; Lopez-Vidriero, I.; Manuel Franco-Zorrilla, J.; Parcy, F.; Panigrahi, K.; Wigge, P.; Nanao, M.; Zubieta, C. 10.1101/584854 — plant biology — Posted on 2019-03-21 1171 Arabidopsis S2Lb links AtCOMPASS-like and SDG2 activity in histone H3 Lys-4 trimethylation independently from histone H2B monoubiquitination Fiorucci, A.-S.; Bourbousse, C.; Concia, L.; Rougee, M.; Deton-Cabanillas, A.-F.; Zabulon, G.; Layat, E.; Latrasse, D.; Kim, S.; Chaumont, N.; Lombard, B.; Stroebel, D.; Lemoine, S.; Mohammad, A.; Blugeon, C.; Loew, D.; Bailly, C.; Bowler, C.; Benhamed, M.; Barneche, F. 10.1101/583724 — plant biology — Posted on 2019-03-21 1172 Leaf shape is a predictor of fruit quality and cultivar performance in tomato Rowland, S. D.; Zumstein, K.; Nakayama, H.; Cheng, Z.; Flores, A. M.; Chitwood, D. H.; Maloof, J. N.; Sinha, N. R. 10.1101/584466 — plant biology — Posted on 2019-03-21 1173 Biophysical modeling of VIM to assess contributions of oscillatory activity to essential tremor Lee, S.; Segar, D. J.; Asaad, W.; Jones, S. 10.1101/339846 — neuroscience — Posted on 2019-03-21 1174 Sex differences in gene expression in the human fetal brain O'Brien, H. E.; Hannon, E.; Jeffries, A. R.; Davies, W.; Hill, M. J.; Anney, R. J.; O'Donovan, M. C.; Mill, J.; Bray, N. J. 10.1101/483636 — genomics — Posted on 2019-03-21 1175 Mutational profiling of lipomas Kanojia, D.; Dakle, P.; Mayakonda, A.; Parameswaran, R.; Puhaindran, M. E.; Min, V. L. K.; Madan, V.; Koeffler, H. P. 10.1101/585307 — genomics — Posted on 2019-03-21 1176 A meta-analysis of genome-wide association studies of epigenetic age acceleration Gibson, J.; Russ, T.; Clarke, T.-K.; Howard, D. M.; Evans, K.; Walker, R. M.; Bermingham, M.; Morris, S.; Campbell, A.; Hayward, C.; Murray, A.; Porteous, D.; Horvath, S.; Lu, A.; McIntosh, A.; Whalley, H.; Marioni, R. 10.1101/585299 — genetics — Posted on 2019-03-21 1177 Clinical pattern of antibiotic overuse and misuse in primary healthcare hospitals in the southwest of China Chang, Y.; Chusri, S.; Sangthong, R.; McNeil, E.; Hu, J.; Du, W.; Li, D.; Fan, X.; Zhou, H.; Chongsuvivatwong, V.; Tang, L. 10.1101/585257 — epidemiology — Posted on 2019-03-21 1178 The land-use dynamics of potato agrobiodiversity in the highlands of central Peru: a case study of spatial-temporal management across farming landscapes Arce Indacochea, A.; de Haan, S.; Juarez, H.; Plasencia, F.; Burra, D.; Ccanto, R.; Polreich, S.; Scurrah, M. 10.1101/585273 — ecology — Posted on 2019-03-21 1179 miRspongeR: an R/Bioconductor package for the identification and analysis of miRNA sponge interaction networks and modules Zhang, J.; Liu, L.; Xu, T.; Xie, Y.; Zhao, C.; Li, J.; Le, T. D. 10.1101/507749 — bioinformatics — Posted on 2019-03-21 1180 The Long Pentraxin 3 (PTX3) Suppresses Immunity to Cutaneous Leishmaniasis by Negatively Regulating Th17 Response Gupta, G.; Jia, P.; Sharma, R.; Zayats, R.; Viana, S. M.; Shan, L.; Mou, Z.; Boaventura, V. S.; Barral, A.; Murooka, T. T.; Soussi-Gounni, A.; de Oliveira, C. I.; Uzonna, J. E. 10.1101/585315 — immunology — Posted on 2019-03-21 1181 Three-dimensional genome reorganization during mouse spermatogenesis Luo, Z.; Wang, X.; Wang, R.; Chen, J.; Chen, Y.; Xu, Q.; Cao, J.; Gong, X.; Wu, J.; Yang, Y.; Li, W.; Han, C.; Sun, F.; Song, X. 10.1101/585281 — genomics — Posted on 2019-03-21 1182 Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population Ye, Y.; ZHANG, L.; YAN, W.; WANG, A.; WANG, W.; GAO, Z.; TANG, X.; YAN, L.; WAN, Q.; LUO, Z.; QIN, G.; CHEN, L.; WANG, S.; Wang, Y.; MU, Y. 10.1101/585190 — epidemiology — Posted on 2019-03-21 1183 Development and characterization of phytosterol nanoemulsions and self-microemulsifying drug delivery systems Chuanxun, Y.; Xueru, Z.; Risheng, J. 10.1101/585166 — biophysics — Posted on 2019-03-21 1184 Long-term iron deficiency and iron supplementation exacerbate acute DSS-induced colitis and are associated with significant dysbiosis Mahalhal, A.; Burkitt, M. D.; Duckworth, C. A.; Hold, G. L.; Campbell, B. J.; Pritchard, D. M.; Probert, C. S. 10.1101/585174 — pathology — Posted on 2019-03-21 1185 The principle of inverse effectiveness in audiovisual speech perception van Wanrooij, M. M.; van de Rijt, L. P. H.; Roye, A.; Mylanus, E. A. M.; van Opstal, A. J. 10.1101/585182 — neuroscience — Posted on 2019-03-21 1186 Effect of different forage-to-concentrate ratios on the structure of rumen bacteria and its relationship with nutrition levels and real-time methane production in sheep Li, R.; Teng, Z.; Lang, C.; Zhou, H.; Zhong, W.; Ban, Z.; Yan, X.; Yang, H.; Farouk, M. H.; Lou, Y. 10.1101/585208 — microbiology — Posted on 2019-03-21 1187 Method to generate growth and degrowth models obtained from combinations of existing models applied to agrarian sciences Santos, A.; Moreira, G. R.; Gomes-Silva, F.; Brito, C. C. R. d.; Costa, M. L.; Pereira, L. G. R.; Mauricio, R. M.; Azevedo, J. A. G. d.; Pereira, J. M.; Ferreira, A. L.; Filho, M. C. 10.1101/585224 — developmental biology — Posted on 2019-03-21 1188 Decoupling sensory from decisional choice biases in perceptual decision making Linares, D.; Aguilar-Lleyda, D.; Lopez-Moliner, J. 10.1101/062380 — neuroscience — Posted on 2019-03-21 1189 Genetics and evidence for balancing selection of a sex-linked colour polymorphism in a songbird Kim, K.-W.; Jackson, B. C.; Zhang, H.; Toews, D. P. L.; Taylor, S. A.; Greig, E. I.; Lovette, I. J.; Liu, M. M.; Davison, A.; Griffith, S. C.; Zeng, K.; Burke, T. 10.1101/437111 — evolutionary biology — Posted on 2019-03-21 1190 Multiplexing cell-cell communication Sexton, J. T.; Tabor, J. J. 10.1101/584664 — synthetic biology — Posted on 2019-03-21 1191 Acute lymphoblastic leukemia cells image analysis with deep bagging ensemble learning Liu, Y.; Long, F. 10.1101/580852 — pathology — Posted on 2019-03-21 1192 Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae Tesniere, C.; Bessiere, C.; Pradal, M.; Sanchez, I.; Blondin, B.; Bigey, F. 10.1101/428979 — microbiology — Posted on 2019-03-21 1193 variant2literature: full text literature search for genetic variants Lin, Y.-H.; Lu, Y.-C.; Hsu, J. S.; Lee, K.-H.; Cheng, Y.-W.; Chen, Y.-C.; Chen, T.-F.; Tu, C.-T.; Hsu, C.-M.; Chou, C.-C.; Chen, P.-L.; Tu, Y.-C. E.; Chen, C.-Y. 10.1101/583450 — genetics — Posted on 2019-03-21 1194 An Exon Skipping Screen Identifies Antitumor Drugs That Are Potent Modulators of Pre-mRNA Splicing, Suggesting New Therapeutic Applications Shi, Y.; Bray, W.; Smith, A. J.; Zhou, W.; Calaoagan, J.; Lagisetti, C.; Sambucetti, L.; Crews, P.; Lokey, R. S.; Webb, T. R. 10.1101/584441 — cancer biology — Posted on 2019-03-21 1195 Enchained growth and cluster dislocation: a possible mechanism for microbiota homeostasis Bansept, F.; Moor-Schumann, K.; Diard, M.; Hardt, W.-D.; Wetter Slack, E.; Loverdo, C. 10.1101/298059 — biophysics — Posted on 2019-03-21 1196 The Arrival of Steppe and Iranian Related Ancestry in the Islands of the Western Mediterranean Fernandes, D. M.; Mittnik, A.; Olalde, I.; Lazaridis, I.; Cheronet, O.; Rohland, N.; Mallick, S.; Bernardos, R.; Broomandkhoshbacht, N.; Carlsson, J.; Culleton, B. J.; Ferry, M.; Gamarra, B.; Lari, M.; Mah, M.; Michel, M.; Modi, A.; Novak, M.; Oppenheimer, J.; Sirak, K. A.; Stewardson, K.; Vai, S.; Camaros, E.; Calo, C.; Catalano, G.; Cueto, M.; Forgia, V.; Lozano, M.; Marini, E.; Micheletti, M.; Micciche, R. M.; Palombo, M. R.; Ramis, D.; Schimmenti, V.; Sureda, P.; Teira, L.; Teschler-Nicola, M.; Kennett, D. J.; Lalueza-Fox, C.; Patterson, N.; Sineo, L.; Caramelli, D.; Pinhasi, R.; Reich, D. 10.1101/584714 — genomics — Posted on 2019-03-21 1197 Transcription-coupled repair and mismatch repair contribute towards preserving genome integrity at mononucleotide repeat tracts Georgakopoulos-Soares, I.; Koh, G.; Jiricny, J.; Hemberg, M.; Nik-Zainal, S. 10.1101/584342 — genomics — Posted on 2019-03-21 1198 Moments reconstruction and local dynamic range compression of high order Superresolution Optical Fluctuation Imaging Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S. 10.1101/500819 — bioengineering — Posted on 2019-03-21 1199 Identification of histological features to predict MUC2 expression in colon cancer tissues Periyakoil, P. K.; Clarke, M.; Sahoo, D. 10.1101/584292 — cancer biology — Posted on 2019-03-21 1200 Long-term exposure to daily ethanol injections in DBA2/J and Swiss mice: Lessons for the interpretation of ethanol sensitization Didone, V.; van Ingelgom, T.; Tirelli, E.; Quertemont, E. 10.1101/584102 — neuroscience — Posted on 2019-03-21 1201 Implementation of Design of Experiments (DOE) for Optimization of Feeding Strategy and Glyco-Engineering of Trastuzumab Biosimilar Mahboudi, R.; Samavat, S.; Afrah, A.; Khorshidtalab, M.; Fadaei Tehran, A.; Motahari, P.; Jafari, F.; Maleknia, S. 10.1101/584144 — bioengineering — Posted on 2019-03-21 1202 SULTA4A1 modulates synaptic development and function by promoting the formation of PSD-95/NMDAR complex Verpelli, C.; Culotta, L.; Terragni, B.; Vinci, E.; Sessa, A.; Broccoli, V.; Mantegazza, M. 10.1101/583419 — neuroscience — Posted on 2019-03-21 1203 Heterologous Expression of Human Norovirus GII.4 VP1 Leads to Assembly of T=4 Virus-Like Particles Devant, J.; Hofhaus, G.; Bhella, D.; Hansman, G. 10.1101/583385 — molecular biology — Posted on 2019-03-21 1204 Construction and validation of EGFP-expressing Staphylococcus aureus clinical strains for adhesion and internalization assays on epithelial cells Charaoui-Boukerzaza, S.; Morgene, M. F.; Rigaill, J.; Audoux, E.; He, Z.; Grattard, F.; Carricajo, A.; Pozzetto, B.; Berthelot, P.; Botelho-Nevers, E.; Verhoeven, P. O. 10.1101/584086 — microbiology — Posted on 2019-03-21 1205 Evidence that viruses, particularly SIV, drove genetic adaptation in natural populations of eastern chimpanzees Schmidt, J. M.; de Manuel, M.; Marques-Bonet, T.; Castellano, S.; Andres, A. M. 10.1101/582411 — evolutionary biology — Posted on 2019-03-21 1206 Seroprevalence of zoonotic diseases (leptospirosis and Japanese encephalitis) in swine in ten provinces of Vietnam: a Bayesian approach to estimate prevalence Lee, H. S.; Thanh, T. L.; Ly, N. K.; Nguyen-Viet, H.; Thakur, K. K.; Grace, D. 10.1101/584151 — epidemiology — Posted on 2019-03-21 1207 Time-to-target explains task-dependent modulation of temporal feedback gain evolution Cesonis, J.; Franklin, D. 10.1101/582874 — neuroscience — Posted on 2019-03-21 1208 Multiparasitism among Schoolchildren of Akonolinga, Nyong et Mfoumou Division, Centre Region of Cameroon OYONO, M. G.; LEHMAN, L. G.; FOSSO, S.; BILONG BILONG, C. F. 10.1101/584318 — epidemiology — Posted on 2019-03-21 1209 Krüppel-like factor 2- induced microRNAs: implications for treatment of pulmonary hypertension Sindi, H.; Russomanno, G.; Kyeong Beom, J.; Abdul-Salam, V. B.; Chaudhry, B. Q.; Ainscough, A.; Szulcek, R.; Bogaard, H. J.; Morgan, C.; Pullamsetti, S. S.; Alzaydi, M.; Rhodes, C.; Grünig, E.; Eichstaedt, C.; Wilkins, M. R.; Wojciak-Stothard, B. 10.1101/583633 — cell biology — Posted on 2019-03-21 1210 Simulations reveal challenges to artificial community selection and possible strategies for success Xie, L.; Yuan, A. E.; Shou, W. 10.1101/264689 — evolutionary biology — Posted on 2019-03-20 1211 treeClust improves protein co-regulation analysis due to robust selectivity for close linear relationships Kustatscher, G.; Grabowski, P.; Rappsilber, J. 10.1101/578971 — systems biology — Posted on 2019-03-20 1212 Tuned normalization in perceptual decision-making circuits can explain seemingly suboptimal confidence behavior Maniscalco, B.; Odegaard, B.; Grimaldi, P.; Cho, S. H.; Basso, M. A.; Lau, H.; Peters, M. A. K. 10.1101/558858 — neuroscience — Posted on 2019-03-20 1213 Prediction of combination therapies based on topological modeling of the immune signaling network in Multiple Sclerosis Bernardo-Faura, M.; Rinas, M.; Wirbel, J.; Pertsovskaya, I.; Pliaka, V.; Messinis, D. E.; Vila, G.; Sakellaropoulos, T.; Faigle, W.; Stridh, P.; Behrens, J. R.; Olsson, T.; Martin, R.; Paul, F.; Alexopoulos, L. G. G.; Villoslada, P.; Saez-Rodriguez, J. 10.1101/541458 — systems biology — Posted on 2019-03-20 1214 Cross-transmission is not the source of new Mycobacterium abscessus infections in a multi-centre cohort of cystic fibrosis patients Doyle, R. M.; Rubio, M.; Dixon, G.; Hartley, J.; Klein, N.; Coll, P.; Harris, K. A. 10.1101/582684 — microbiology — Posted on 2019-03-20 1215 Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration Hsu, A. Y.; Wang, D.; Liu, S.; Lu, J.; Sobreira, R. S.; Bennin, D. A.; Huttenlocher, A.; Umulis, D. M.; Wan, J.; Deng, Q. 10.1101/574335 — immunology — Posted on 2019-03-20 1216 Non-lethal oxidative stress boosts bacterial survival and evolvability under lethal exposure Rodriguez Rojas, A.; Kim, J.; Johnston, P. R.; Makarova, O.; Eravci, M.; Weise, C.; Hengge, R.; Rolff, J. 10.1101/575134 — evolutionary biology — Posted on 2019-03-20 1217 LSO:Ce Inorganic Scintillators are Biocompatible with Neuronal and Circuit Function Bartley, A. F.; Abiraman, K.; Stewart, L. T.; Hossain, M. I.; Gahan, D. M.; Kamath, A. V.; Burdette, M. K.; Andrabe, S.; Foulger, S. H.; McMahon, L. L.; Dobrunz, L. E. 10.1101/579722 — neuroscience — Posted on 2019-03-20 1218 Age-related alterations in functional connectivity along the longitudinal axis of the hippocampus and its subfields Stark, S. M.; Frithsen, A.; Stark, C. E. 10.1101/577361 — neuroscience — Posted on 2019-03-20 1219 Host-pathogen transcriptomics of macrophages, Mucorales and their endosymbionts: a polymicrobial pas de trois Sephton-Clark, P.; Munoz, J. F.; Itabangi, H.; Voelz, K.; Cuomo, C.; Ballou, E. 10.1101/580746 — microbiology — Posted on 2019-03-20 1220 A stable pollination environment limits current but not potential evolution of floral traits Castellanos, M. C.; Montero-Pau, J.; Ziarsolo, P.; Blanca, J. M.; Canizares, J.; Pausas, J. G. 10.1101/581827 — evolutionary biology — Posted on 2019-03-20 1221 Frequent sugar feeding behavior by Aedes aegypti in Bamako, Mali makes them ideal candidates for control with attractive toxic sugar baits (ATSB) Sisoko, F.; Junnila, A.; Traore, M.; Traore, S. F.; Doumbia, S.; Dembele, S. M.; Schlein, Y.; Gergely, P.; Xue, R.-d.; Arheart, K. L.; Revay, E. E.; Kravchenko, V. D.; Beier, J. C.; Muller, G. C. 10.1101/574095 — ecology — Posted on 2019-03-20 1222 Chemical screening pipeline for identification of specific plant autophagy modulators Dauphinee, A. N.; Cardoso, C.; Dalman, K.; Ohlsson, J. A.; Berglund Fick, S.; Robert, S.; Hicks, G. R.; Bozhkov, P. V.; Minina, E. A. 10.1101/569327 — plant biology — Posted on 2019-03-20 1223 The interaction of compliance and activation on the force-length operating range and force generating capacity of skeletal muscle Cox, S. M.; Easton, K. L.; Cromie Lear, M.; Marsh, R.; Delp, S.; Rubenson, J. 10.1101/580027 — physiology — Posted on 2019-03-20 1224 Experimental colitis drives enteric alpha-synuclein accumulation and Parkinson-like brain pathology Grathwhohl, S.; Quansah, E.; Maroof, N.; Steiner, J. A.; Spycher, L.; Benmansour, F.; Duran-Pacheco, G.; Siebourg-Polster, J.; Oroszlan-Szovik, K.; Remy, H.; Haenggi, M.; Stawiski, M.; Sehlhausen, M.; Maliver, P.; Wolfert, A.; Emrich, T.; Madaj, Z.; Escobar Galvis, M. L.; Mueller, C.; Herrmann, A.; Brundin, P.; Britschgi, M. 10.1101/505164 — neuroscience — Posted on 2019-03-20 1225 Disentangling presentation and processing times in the brain Caplette, L.; Ince, R. A. A.; Jerbi, K.; Gosselin, F. 10.1101/566042 — neuroscience — Posted on 2019-03-20 1226 Identification of Physiological Response Functions to Correct for Fluctuations in Resting-State fMRI related to Heart Rate and Respiration Kassinopoulos, M.; Mitsis, G. D. 10.1101/512855 — neuroscience — Posted on 2019-03-20 1227 In vivo microscopy reveals the impact of Pseudomonas aeruginosa social interactions on host colonization Rezzoagli, C.; Granato, E.; Kuemmerli, R. 10.1101/488262 — microbiology — Posted on 2019-03-20 1228 Parasite histones mediate leak and coagulopathy in cerebral malaria Moxon, C. A.; Alhamdi, Y.; Storm, J.; Toh, J.; Ko, J. Y.; Murphy, G.; Taylor, T.; Seydel, K.; Kampondeni, S.; Potchen, M.; O'Donnell, J.; O'Regan, N.; Wang, G.; Garcia-Cardena, G.; Molyneux, M.; Craig, A.; Abrams, S.; Toh, C.-H. 10.1101/563551 — microbiology — Posted on 2019-03-20 1229 UK phenomics platform for developing and validating EHR phenotypes: CALIBER Denaxas, S.; Gonzalez-Izquierdo, A.; Direk, K.; Fitzpatrick, N.; Fatemifar, G.; Banerjee, A.; Dobson, R.; Howe, L. J.; Kuan, V.; Lumbers, T.; Pasea, L.; Patel, R.; Shah, A. D.; Hingorani, A.; Sudlow, C.; Hemingway, H. 10.1101/539403 — epidemiology — Posted on 2019-03-20 1230 FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation Hoffmann, I.; Richter, K. T.; Kschonsak, Y. T.; Vodicska, B. 10.1101/493791 — cell biology — Posted on 2019-03-20 1231 A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase Buchan, K. D.; Prajsnar, T. K.; Ogryzko, N. V.; de Jong, N. W.; van Gent, M.; Kolata, J.; Foster, S. J.; Van Strijp, J. A. G. A.; Renshaw, S. A. 10.1101/456541 — immunology — Posted on 2019-03-20 1232 Efa6 protects axons and regulates their growth and branching through eliminating off-track microtubules at the cortex Qu, Y.; Hahn, I.; Lees, M.; Parkin, J.; Voelzmann, A.; Dorey, K.; Rathbone, A.; Friel, C.; Allan, V.; Okenve-Ramos, P.; Sanchez-Soriano, N.; Prokop, A. 10.1101/385658 — cell biology — Posted on 2019-03-20 1233 Quantifying GC-biased gene conversion in great ape genomes using polymorphism-aware models Borges, R.; Szöllosi, G.; Kosiol, C. 10.1101/380246 — genetics — Posted on 2019-03-20 1234 Tissue-specific MicroRNA Expression Alters Cancer Susceptibility Conferred by a TP53 Noncoding Variant LI, Y. 10.1101/582478 — cancer biology — Posted on 2019-03-20 1235 Enhancing Boolean networks with continuous logical operators and edge tuning Poret, A.; Monteiro Sousa, C.; Boissel, J.-P. 10.1101/584243 — bioinformatics — Posted on 2019-03-20 1236 Deep representation learning for domain adaptable classification of infrared spectral imaging data Raulf, A. P.; Butke, J.; Kuepper, C.; Grosserueschkamp, F.; Gerwert, K.; Mosig, A. 10.1101/584227 — bioinformatics — Posted on 2019-03-20 1237 Non-proliferative adult neurogenesis in neural crest-derived stem cells isolated from human periodontal ligament. Bueno, C.; Martinez-Morga, M.; Martinez, S. 10.1101/325613 — neuroscience — Posted on 2019-03-20 1238 Unveiling functional motions based on point mutations in biased signaling systems: A normal mode study on Nerve Growth Factor bound to TrkA De Resende Lara, P. T.; Perahia, D.; Scott, A. L.; Braz, A. S. K. 10.1101/584300 — bioinformatics — Posted on 2019-03-20 1239 Time-series expression profiling of sugarcane leaves infected with Puccinia kuehnii reveals an ineffective defense system leading to susceptibility Correr, F. H.; Kenichi Hosaka, G.; Perez Gomez, S. G.; Cicarelli Cia, M.; Barros Monteiro Vitorello, C. A.; Aranha Camargo, L. E.; Massola Junior, N. S.; Sampaio Carneiro, M.; Rodrigues Alves Margarido, G. 10.1101/584276 — genomics — Posted on 2019-03-20 1240 Cabbage stem flea beetles (Psylliodes chrysocephala L.) susceptibility to pyrethroids and tolerance to thiacloprid in the Czech Republic Stara, J.; Kocourek, F. 10.1101/584250 — zoology — Posted on 2019-03-20 1241 Microbial metabolite deoxycholic acid shapes microbiota against Campylobacter jejuni chicken colonization Alrubaye, B.; Abraha, M.; Almansour, A.; Bansal, M.; Wang, H.; Kwon, Y. M.; Huang, Y.; Hargis, B.; Sun, X. 10.1101/584284 — microbiology — Posted on 2019-03-20 1242 Cardiac remodeling after six weeks of high-intensity interval training to exhaustion in endurance-trained males Mahjoub, H.; Le Blanc, O.; Paquette, M.; Imhoff, S.; Labrecque, L.; Drapeau, A.; Poirier, P.; Bedard, E.; Pibarot, P.; Brassard, P. 10.1101/582924 — physiology — Posted on 2019-03-20 1243 A normative study of modified spatial context memory test in middle and older individuals Kuo, H.-C.; Wang, H.-M.; Huang, Y.-P.; Kuo, H.-Y. 10.1101/584136 — neuroscience — Posted on 2019-03-20 1244 Nintedanib ameliorates experimental pulmonary arterial hypertension via inhibition of endothelial mesenchymal transition and smooth muscle cell proliferation Tsutsumi, T.; Nagaoka, T.; Yoshida, T.; Wang, L.; Kuriyama, S.; Suzuki, Y.; Nagata, Y.; Harada, N.; Kodama, Y.; Takahashi, F.; Morio, Y.; Takahashi, K. 10.1101/584110 — physiology — Posted on 2019-03-20 1245 Inhibition of Osteoblast Proliferation and Migration by Exogenous and Endogenous Formaldehyde Teng, X.; Huang, W.; Yu, H.; Wang, P.; Li, W.; Chen, Z.; Fan, D. 10.1101/584052 — cell biology — Posted on 2019-03-20 1246 Evaluation of PicoGreen variants for use in microscopy and flow cytometry Khatoo, M.; Yang, J.; Gee, K. R.; Gasser, S. 10.1101/584037 — cancer biology — Posted on 2019-03-20 1247 Mate choice confers direct benefits to females of Anastrepha fraterculus (Diptera: Tephritidae) Segura, D. F.; Bachmann, G. E.; Devescovi, F.; Nussenbaum, A. L.; Milla, F. H.; Shelly, T. E.; Cladera, J. L.; Fernandez, P. C.; Vera, M. T. 10.1101/584128 — animal behavior and cognition — Posted on 2019-03-20 1248 Translation and cross-cultural adaptation to Portuguese of The Patient- And Nutrition-Derived Outcome Risk Assessment Score (PANDORA) Lima, J. B. d.; Campos, M. B.; Ribeiro, L. S.; Taboada, M. I. S. 10.1101/584078 — pathology — Posted on 2019-03-20 1249 Detection of EGFR deletion using unique RepSeq technology Vinayagamoorthy, T.; Qin, D.; Ye, F.; Zhong, M. 10.1101/584045 — genomics — Posted on 2019-03-20 1250 Cell cycle inhibitor Whi5 records environmental information to coordinate growth and division in yeast Qu, Y.; Jiang, J.; Liu, X.; Wei, P.; Yang, X.; Tang, C. 10.1101/583666 — systems biology — Posted on 2019-03-20 1251 The signaling mechanism of Hcy-induced atrial fibrosis mediated by TRPC3 Han, L.; Li, J.; Tang, Y.; Cheng, X.; Hong, K.; Wu, Y. 10.1101/583740 — molecular biology — Posted on 2019-03-20 1252 Tbet promotes NK cell bone marrow egress via CXCR6 expression Cuff, A. O.; Perchet, T.; Dertschnig, S.; Golub, R.; Male, V. 10.1101/583575 — immunology — Posted on 2019-03-20 1253 Quaternary structural convergence and structural diversification of prion assemblies at the early replication stage Igel-Egalon, A.; Lafferriere, F.; Moudjou, M.; Merzach, M.; Knapple, T.; Herzog, L.; Reine, F.; Doumic, M.; Rezaei, H.; Beringue, V. 10.1101/583781 — biochemistry — Posted on 2019-03-20 1254 NRT2.1 phosphorylation prevents root high affinity nitrate uptake activity in Arabidopsis thaliana Jacquot, A.; Chaput, V.; Mauries, A.; Li, Z.; Tillard, P.; Fizames, C.; Bonillo, P.; Bellegarde, F.; Laugier, E.; Santoni, V.; Hem, S.; Martin, A.; Gojon, A.; Schulze, W.; Lejay, L. 10.1101/583542 — plant biology — Posted on 2019-03-20 1255 Dlx5 and Dlx6 expression in GABAergic neurons controls behavior, metabolism, healthy aging and lifespan. de Lombares, C.; Heude, E.; Alfama, G.; Fontaine, A.; Hassouna, R.; Vernochet, C.; de Chaumont, F.; Olivo-Marin, J.-C.; Ey, E.; Parnaudeau, S.; Tronche, F.; Bourgeron, T.; Luquet, S.; Levi, G.; Narboux-Neme, N. 10.1101/583708 — physiology — Posted on 2019-03-20 1256 Interleukin 17 and senescence regulate the foreign body response Chung, L.; Maestas, D.; Lebid, A.; Mageau, A.; Rosson, G. D.; Wu, X.; Wolf, M. T.; Tam, A.; Wang, X.; Vanderzee, I.; Andorko, J. I.; Narain, R.; Sadlter, K.; Fan, H.; Cihakova, D.; Jourdan Le Saux, C.; Housseau, F.; Pardoll, D.; Elisseeff, J. 10.1101/583757 — immunology — Posted on 2019-03-20 1257 Optimizing the power to identify the genetic basis of complex traits with Evolve and Resequence studies Vlachos, C.; Kofler, R. 10.1101/583682 — evolutionary biology — Posted on 2019-03-20 1258 A significant role for the circadian clock in the long-term water use efficiency of Arabidopsis Simon, N. M.; Comben, N. E.; Hetherington, A. M.; Dodd, A. 10.1101/583526 — plant biology — Posted on 2019-03-20 1259 An evaluation of pool-sequencing transcriptome-based exon capture for population genomics of non-model species Deleury, E.; Guillemaud, T.; Blin, A.; Lombaert, E. 10.1101/583534 — genomics — Posted on 2019-03-20 1260 Epstein-Barr virus inactivates the transcriptome and disrupts the chromatin architecture of its host cell in the first phase of lytic reactivation Buschle, A.; Mrozek-Gorska, P.; Krebs, S.; Blum, H.; Cernilogar, F. M.; Schotta, G.; Pich, D.; Straub, T.; Hammerschmidt, W. 10.1101/573659 — cell biology — Posted on 2019-03-20 1261 Modular actin nano-architecture enables podosome protrusion and mechanosensing van den Dries, K.; Nahidiazar, L.; Slotman, J. A.; Meddens, M. B. M.; Pandzic, E.; Joosten, B.; Ansems, M.; Schouwstra, J.; Meijer, A.; Steen, R.; Wijers, M.; Fransen, J.; Houtsmuller, A. B.; Wiseman, P. W.; Jalink, K.; Cambi, A. 10.1101/583492 — cell biology — Posted on 2019-03-20 1262 A stochastic hybrid model for DNA replication incorporating protein mobility dynamics Windhager, J.; Paine, A.; Nathanailidou, P.; Tasiudi, E.; Rodriguez Martinez, M.; Lygerou, Z.; Lygeros, J.; Rapsomaniki, M. A. 10.1101/583187 — bioinformatics — Posted on 2019-03-20 1263 Engineering strategy and vector library for the rapid generation of modular light-controlled protein-protein interactions Tichy, A.-M.; Gerrard, E. J.; Legrand, J. M. D.; Hobbs, R. M.; Janovjak, H. 10.1101/583369 — synthetic biology — Posted on 2019-03-20 1264 Knowledge and attitudes among life scientists towards reproducibility within journal articles. Kaimaklioti Samota, E.; P. Davey, R. 10.1101/581033 — scientific communication and education — Posted on 2019-03-20 1265 A regulatory RNA is associated to invasive meningococcal disease in Europe Karlsson, J.; Eichner, H.; Jacobsson, S.; Loh, E. 10.1101/583476 — microbiology — Posted on 2019-03-20 1266 Efferocytosis perpetuates substance accumulation inside macrophage populations Ford, H. Z.; Zeboudj, L.; Purvis, G. S. D.; ten Bokum, A.; Zarebski, A. E.; Bull, J. A.; Byrne, H. M.; Myerscough, M. R.; Greaves, D. R. 10.1101/583484 — immunology — Posted on 2019-03-20 1267 Familial influences on Neuroticism and Education in the UK Biobank Cheesman, R.; Coleman, J.; Rayner, C.; Purves, K. L.; Morneau-Vaillancourt, G.; Glanville, K.; Choi, S. W.; Breen, G.; Eley, T. 10.1101/582627 — genomics — Posted on 2019-03-20 1268 Genetic association study of psychotic experiences in UK Biobank Legge, S. E.; Jones, H. J.; Kendall, K. M.; Pardinas, A. F.; Menzies, G.; Bracher-Smith, M.; Escott-Price, V.; Rees, E.; Davis, K. A. S.; Hotopf, M.; Savage, J. E.; Posthuma, D.; Holmans, P.; Kirov, G.; Owen, M. J.; O'Donovan, M.; Zammit, S.; Walters, J. T. 10.1101/583468 — genetics — Posted on 2019-03-20 1269 Population genomics of the facultatively asexual duckweed Spirodela polyrhiza Ho, E.; Bartkowska, M.; Wright, S.; Agrawal, A. 10.1101/583021 — evolutionary biology — Posted on 2019-03-20 1270 Tracking trends in monarch abundances over the 20th century is currently impossible using museum records: a response to Boyle et al. (2019) Ries, L.; Zipkin, E. F.; Guralnick, R. P. 10.1101/581801 — ecology — Posted on 2019-03-20 1271 Nuclear pores as versatile reference standards for quantitative superresolution microscopy Thevathasan, J. V.; Kahnwald, M.; Cieslinski, K.; Hoess, P.; Peneti, S. K.; Reitberger, M.; Heid, D.; Kasuba, K. C.; Hoerner, S. J.; Li, Y.; Wu, Y.-L.; Mund, M.; Matti, U.; Pereira, P. M.; Henriques, R.; Nijmeijer-Winter, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Ellenberg, J.; Ries, J. 10.1101/582668 — biophysics — Posted on 2019-03-20 1272 Neutrophil-derived extracellular vesicles: proinflammatory trails and anti-inflammatory microvesicles Youn, Y.-J.; Shrestha, S.; Kim, J.-K.; Lee, Y.-B.; Lee, J. H.; Hur, K.; Mali, N. M.; Nam, S.-W.; Kim, S.-H.; Song, D.-K.; Jin, H. K.; Bae, J.-s.; Hong, C.-W. 10.1101/583435 — immunology — Posted on 2019-03-20 1273 Autistic traits lower the flexibility of information sampling: insights from a two-stage decision model Lu, H.; Yi, L.; Zhang, H. 10.1101/582783 — neuroscience — Posted on 2019-03-20 1274 Differential N-end rule degradation of RIN4/NOI fragments generated by the AvrRpt2 effector protease Goslin, K.; Eschen-Lippold, L.; Naumann, C.; Linster, E.; Sorel, M.; Klecker, M.; de Marchi, R.; Kind, A.; Wirtz, M.; Lee, J.; Dissmeyer, N.; Graciet, E. 10.1101/583054 — plant biology — Posted on 2019-03-20 1275 Non-medical prescribing policy in the United Kingdom National Health Service: systematic review and narrative synthesis Graham-Clarke, E.; Rushton, A.; Noblet, T.; Marriott, J. 10.1101/582718 — pharmacology and toxicology — Posted on 2019-03-20 1276 Phosphatidylinositol 4,5 bisphosphate controls the cis and trans interactions of synaptotagmin 1 Nyenhuis, S. B.; Thapa, A.; Cafiso, D. S. 10.1101/582965 — neuroscience — Posted on 2019-03-20 1277 Effect of Antimicrobial Stewardship with Rapid MALDI-TOF Identification and Vitek 2 Antimicrobial Susceptibility Testing on Hospitalization Outcome Cavalieri, S.; Kwon, S. S.; Vivekanandan, R.; Ased, S.; Carroll, C.; Anthone, J.; Schmidt, D.; Baysden, M.; Destache, C. J. 10.1101/581991 — microbiology — Posted on 2019-03-20 1278 Reductive dehalogenase gene biomarkers differentiate 1,1,1-trichloroethane from 1,1-dichloroethane dechlorination in microcosms and at a field site treated with granular ZVI and guar gum Yang, M. I.; Previdsa, M.; Edwards, E. A.; Sleep, B. E. 10.1101/583229 — microbiology — Posted on 2019-03-20 1279 Whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants Zhang, S.; He, Y.; Liu, H.; Zhai, H.; Huang, D.; Yi, X.; Dong, X.; Wang, Z.; Zhao, K.; Zhou, Y.; Wang, J.; Yao, H.; Xu, H.; Yang, Z.; Sham, P. C.; Chen, K.; Li, M. J. 10.1101/583237 — genomics — Posted on 2019-03-20 1280 Analysis-ready datasets for insecticide resistance phenotype and genotype frequency in African malaria vectors Moyes, C.; Wiebe, A.; Gleave, K.; Trett, A.; Hancock, P. A.; Padonou, G. G.; Mouhamadou, C. S.; Sovi, A.; Abuelmaali, S. A.; Ochomo, E.; Antonio-Nkondjio, C.; Dengela, D.; Kawada, H.; Dabire, R. K.; Donnelly, M. J.; Mbogo, C.; Fornadel, C.; Coleman, M. 10.1101/582510 — zoology — Posted on 2019-03-20 1281 Epistatic Transcription Factor Networks Differentially Modulate Arabidopsis Growth and Defense Li, B.; Tang, M.; Caseys, C.; Nelson, A.; Zhou, M.; Zhou, X.; Brady, S.; Kliebenstein, D. 10.1101/583047 — plant biology — Posted on 2019-03-20 1282 Variations in Structural MRI Quality Impact Measures of Brain Anatomy: Relations with Age Gilmore, A.; Buser, N. J.; Hanson, J. L. 10.1101/581876 — neuroscience — Posted on 2019-03-20 1283 Identification and classification of hubs in miRNA target gene networks in human neural stem/progenitor cells following Japanese encephalitis virus infection Mukherjee, S.; Akbar, I.; Bhagat, R.; Hazra, B.; Bhattacharyya, A.; Seth, P.; Roy, D.; Basu, A. 10.1101/581983 — microbiology — Posted on 2019-03-20 1284 Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell cycle arrest Cho, S.; Vashisth, M.; Abbas, A.; Majkut, S.; Vogel, K.; Xia, Y.; Ivanovska, I. L.; Irianto, J.; Tewari, M.; Zhu, K.; Tichy, E. D.; Mourkioti, F.; Tang, H.-Y.; Greenberg, R.; Prosser, B. L.; Discher, D. E. 10.1101/583179 — cell biology — Posted on 2019-03-20 1285 MM-MRE: a new technique to quantify individual muscle forces during isometric tasks of the wrist using MR elastography Zonnino, A.; Smith, D. R.; Delgorio, P. L.; Johnson, C. L.; Sergi, F. 10.1101/582825 — bioengineering — Posted on 2019-03-20 1286 Dissecting the cognitive phenotype of post-stroke fatigue using drift diffusion modeling of sustained attention Ulrichsen, K. M.; Alnaes, D.; Kolskaar, K. K.; Richard, G.; Sanders, A.-M.; Doerum, E. S.; Ihle-Hansen, H.; Pedersen, M. L.; Tornaas, S.; Nordvik, J. E.; Westlye, L. T. 10.1101/582502 — neuroscience — Posted on 2019-03-20 1287 Critical Variables to be Considered when Attempting to Estimate Blood Ethanol Concentrations in Rats from g/kg Exposure Data Dannenhoffer, C. A.; Hosova, D.; Dang, S.; Dang, U.; Spear, L. P. 10.1101/582361 — neuroscience — Posted on 2019-03-20 1288 Region-specific blood-brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease Sekhar, G. N.; Fleckney, A. L.; Boyanova, S. T.; Rupawala, H.; Lo, R.; Wang, H.; Farag, D. B.; Rahman, K. M.; Broadstock, M.; Reeves, S.; Thomas, S. A. 10.1101/582387 — neuroscience — Posted on 2019-03-20 1289 Diverse commensal E. coli clones and plasmids disseminate antimicrobial resistance genes in domestic animals and children in a semi-rural community in Ecuador Salinas, L.; Cardenas, P. A.; Johnson, T. J.; Vasco, K.; Graham, J.; Trueba, G. 10.1101/581967 — microbiology — Posted on 2019-03-20 1290 Identifying the neural representation of fast and slow states in force field adaptation via fMRI Farrens, A. J.; Sergi, F. 10.1101/582791 — bioengineering — Posted on 2019-03-20 1291 Individual variation in the attribution of incentive salience to social cues Fitzpatrick, C. J.; Morrow, J. D. 10.1101/582254 — animal behavior and cognition — Posted on 2019-03-20 1292 Deletion of the creatine transporter gene in neonatal, but not adult, mice lead to cognitive deficits. Udobi, K.; Delcimmuto, N.; Kokenge, A.; Abdulla, Z.; Perna, M.; Skelton, M. 10.1101/582320 — neuroscience — Posted on 2019-03-20 1293 Neural desynchronization and arousal differentially shape brain states for optimal sensory performance Waschke, L.; Tune, S.; Obleser, J. 10.1101/582353 — neuroscience — Posted on 2019-03-20 1294 Rehabilitation promotes the recovery of structural and functional features of healthy neuronal networks after stroke Allegra Mascaro, A. L.; Conti, E.; Lai, S.; Di Giovanna, A. P.; Spalletti, C.; Alia, C.; Panarese, A.; Scaglione, A.; Sacconi, L.; Micera, S.; Caleo, M.; Pavone, F. S. 10.1101/582775 — neuroscience — Posted on 2019-03-20 1295 The use of a virus-derived targeting peptide to selectively kill staphylococcus bacteria with antimicrobial peptides Islam, S. M. A.; Choudhury, A.; Ghidey, M. R.; Kearney, C. M. 10.1101/583161 — molecular biology — Posted on 2019-03-20 1296 Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice Lei, M.; Menon, R.; Manteiga, S.; Alden, N.; Hunt, C.; Alaniz, R. C.; Lee, K.; Jayaraman, A. 10.1101/581975 — microbiology — Posted on 2019-03-20 1297 CELL CYCLE ASYNCHRONY GENERATES DNA DAMAGE AT MITOTIC ENTRY IN POLYPLOID CELLS Nano, M.; Simon, A.; Pennetier, C.; Fraisier, V.; Marthiens, V.; Basto, R. 10.1101/582460 — cell biology — Posted on 2019-03-20 1298 Unsupervised deep learning on biomedical data with BoltzmannMachines.jl Lenz, S.; Hess, M.; Binder, H. 10.1101/578252 — bioinformatics — Posted on 2019-03-20 1299 The Zymoseptoria tritici ORFeome: a functional genomics community resource Chaudhari, Y.; Cairns, T. C.; Sidhu, Y.; Attah, V.; Thomas, G.; Csukai, M.; Talbot, N. J.; Studholme, D. J.; Haynes, K. 10.1101/582205 — systems biology — Posted on 2019-03-20 1300 CRISPR-BEST: a highly efficient DSB-free base editor for filamentous actinomycetes Tong, Y.; Robertsen, H. L.; Blin, K.; Klitgaard, A. K.; Weber, T.; Lee, S. Y. 10.1101/582403 — synthetic biology — Posted on 2019-03-20 1301 Making plants into cost-effective bioreactors for highly active antimicrobial peptides Ghidey, M. R.; Islam, S. M. A.; Pruett, G.; Kearney, C. M. 10.1101/583146 — plant biology — Posted on 2019-03-20 1302 Dosing regimen of gentamicin and the effect of antenatal steroids on clearance in preterm infants Santos, R. P.; Chang, Y.; Oliveira, C. R.; Adams-Huet, B.; Gard, J.; Sanchez, P. J. 10.1101/566125 — pharmacology and toxicology — Posted on 2019-03-20 1303 The Distributed Engram Feldesh, R. 10.1101/583195 — neuroscience — Posted on 2019-03-20 1304 A Critique of Pure Learning: What Artificial Neural Networks can Learn from Animal Brains Zador, A. 10.1101/582643 — neuroscience — Posted on 2019-03-20 1305 Assessing the role of long-noncoding RNA in nucleus accumbens in subjects with alcohol dependence McMichael, G.; Drake, J.; Vornholt, E.; Cresswell, K.; Williamson, V.; Chatzinakos, C.; Mamdani, M.; Hariharan, S.; Kendler, K.; Miles, M.; Kalsi, G.; Riley, B.; Dozmorov, M.; Bacanu, S.-A.; Vladimirov, V. 10.1101/583203 — neuroscience — Posted on 2019-03-20 1306 Comparison of real-time PCR and droplet digital PCR for the detection of Xylella fastidiosa in plants Dupas, E.; Legendre, B.; Olivier, V.; Poliakoff, F.; Manceau, C.; Cunty, A. 10.1101/582288 — molecular biology — Posted on 2019-03-20 1307 CRISPR/Cas9-based mutagenesis frequently provokes on-target mRNA misregulation Tuladhar, R.; Yeu, Y.; Piazza, J. T.; Tan, Z.; Clemenceau, J. R.; Wu, X.; Barrett, Q.; Herbert, J.; Mathews, D.; Kim, J.; Hwang, T. H.; Lum, L. 10.1101/583138 — molecular biology — Posted on 2019-03-20 1308 Effect of partial selfing and polygenic selection on establishment in a new habitat Sachdeva, H. 10.1101/582122 — evolutionary biology — Posted on 2019-03-20 1309 Protein structure without structure determination: direct coupling analysis based on in vitro evolution Fantini, M.; Lisi, S.; de los Rios, P.; Cattaneo, A.; Pastore, A. 10.1101/582056 — evolutionary biology — Posted on 2019-03-20 1310 Training propulsion: Locomotor adaptation to accelerations of the trailing limb Farrens, A. J.; Marbaker, R.; Lilley, M.; Sergi, F. 10.1101/582841 — bioengineering — Posted on 2019-03-20 1311 Combining gene network, metabolic, and leaf-level models show means to future-proof soybean photosynthesis under rising CO2. Kannan, K.; Wang, Y.; Lang, M. M.; Challa, G. S.; Long, S. P.; Marshall-Colon, A. 10.1101/582981 — plant biology — Posted on 2019-03-20 1312 The menstrual cycle is a primary contributor to cyclic variation in women’s mood, behavior, and vital signs Pierson, E.; Althoff, T.; Thomas, D.; Hillard, P.; Leskovec, J. 10.1101/583153 — physiology — Posted on 2019-03-20 1313 Comparative thermal performance of Orbicella franksi at its latitudinal range limits Silbiger, N. J.; Goodbody-Gringley, G.; Bruno, J. F.; Putnam, H. M. 10.1101/583294 — physiology — Posted on 2019-03-20 1314 Active behaviour during early development shapes glucocorticoid reactivity Castillo-Ramirez, L. A.; Ryu, S.; De Marco, R. J. 10.1101/582163 — physiology — Posted on 2019-03-20 1315 MitoToxy Assay: a novel cell-based method for the assessment of metabolic toxicity in a multiwell plate format using a lactate FRET nanosensor, Laconic Contreras, Y.; Ceballo, S.; Arce, R.; Sandoval, P.; Alegria, K.; Barros, F.; San Martin, A. A. 10.1101/583096 — pharmacology and toxicology — Posted on 2019-03-20 1316 Characterizing neuronal synaptic transmission using stochastic hybrid systems Vahdat, Z.; Xu, Z.; Singh, A. 10.1101/582445 — neuroscience — Posted on 2019-03-20 1317 Neuronal histone methyltransferase EZH2 regulates neuronal morphogenesis, synaptic plasticity, and cognitive behavior of mice Zhang, M.; Zhang, Y.; Xu, Q.; Crawford, J.; Qian, C.; Wang, G.-H.; Lewis, E.; Hall, P.; Dolen, G.; Huganir, R. L.; Qian, J.; Dong, X.; Pletnikov, M. V.; Liu, C.-M.; Zhou, F.-Q. 10.1101/582908 — neuroscience — Posted on 2019-03-20 1318 A generic deviance detection principle for cortical On/Off responses, omission response, and mismatch negativity Chien, S.-C.; Maess, B.; Knoesche, T. R. 10.1101/582437 — neuroscience — Posted on 2019-03-20 1319 Coxiella burnetii epitope-specific T-cell responses in chronic Q fever patients Scholzen, A.; Richard, G.; Moise, L.; Hartman, E.; Bleeker-Rovers, C. P.; Reeves, P. M.; Raju Paul, S.; Martin, W. D.; De Groot, A. S.; Poznansky, M. C.; Sluder, A. E.; Garritsen, A. 10.1101/582007 — immunology — Posted on 2019-03-20 1320 DOCK2 sets the threshold for entry into the virtual memory CD8+ T cell compartment by negatively regulating tonic TCR triggering Demissie, E.; Mahajan, V.; Alsufyani, F.; Kumari, S.; Yuen, G. J.; Viswanadham, V.; Tran, J. Q.; Moon, J. J.; Irvine, D. J.; Pillai, S. 10.1101/582486 — immunology — Posted on 2019-03-20 1321 Exclusion and genomic relatedness methods for assignment of parentage using genotyping-by-sequencing data Dodds, K. G.; McEwan, J. C.; Brauning, R.; van Stijn, T. C.; Rowe, S. J.; McEwan, K. M.; Clarke, S. M. 10.1101/582585 — genetics — Posted on 2019-03-20 1322 Sex Solves Haldane’s Dilemma Hickey, D.; Golding, G. B. 10.1101/582536 — evolutionary biology — Posted on 2019-03-20 1323 Trans-generational effects on diapause and life-history-traits of an aphid parasitoid Tougeron, K.; Devogel, M.; van Baaren, J.; Le Lann, C.; Hance, T. 10.1101/582932 — ecology — Posted on 2019-03-20 1324 Microfluidic Rapid and Autonomous Analytical Device (microRAAD) to Detect HIV from Whole Blood Samples Phillips, E. A.; Moehling, T. J.; Ejendal, K. F. K.; Hoilett, O. S.; Byers, K. M.; Basing, L. A.; Jankowski, L. A.; Bennett, J. B.; Lin, L.-K.; Stanciu, L. A.; Linnes, J. C. 10.1101/582999 — bioengineering — Posted on 2019-03-20 1325 Single-stride exposure to pulse torque assistance provided by a robotic exoskeleton at the hip and knee joints McGrath, R. L.; Sergi, F. 10.1101/582866 — bioengineering — Posted on 2019-03-20 1326 A type III CRISPR ancillary ribonuclease degrades its cyclic oligoadenylate activator Athukoralage, J. S.; Graham, S.; Grueschow, S.; Rouillon, C.; White, M. F. 10.1101/582114 — biochemistry — Posted on 2019-03-20 1327 Composition variation of agarwood-associated microbial communities from Aquilaria sinensis Mo, Q.; Fan, C.; Zhou, G.; Fu, H.; Wang, Y. 10.1101/583393 — plant biology — Posted on 2019-03-20 1328 Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1 Skelly, M. J.; Furniss, J. J.; Grey, H. L.; Wong, K.-W.; Spoel, S. H. 10.1101/582296 — plant biology — Posted on 2019-03-20 1329 Strain- or Stress-sensing in mechanochemical patterning by the phytohormone auxin Julien, J.-D.; Pumir, A.; Boudaoud, A. 10.1101/582551 — plant biology — Posted on 2019-03-20 1330 The TMEM106B rs1990621 protective variant is also associated with increased neuronal proportion Li, Z.; Farias, F. G.; Dube, U.; Del Aguila, J. L. L.; Mihindukulasuriya, K. A.; Fernandez, M.-V. V.; Ibanez, L.; Budde, J. P.; Wang, F.; Lake, A. M.; Robles, Y.; Perez, J.; Yang, C.; Bradley, J.; Davenport, R.; Bergmann, K.; Benitez, B. A. A.; Dougherty, J. D.; Harari, O.; Cruchaga, C. 10.1101/583286 — neuroscience — Posted on 2019-03-20 1331 Two fiber pathways connecting amygdala and prefrontal cortex in humans and monkeys Folloni, D.; Sallet, J.; Khrapichev, A. A.; Sibson, N. R.; Verhagen, L.; Mars, R. B. 10.1101/561811 — neuroscience — Posted on 2019-03-20 1332 StretchfMRI: a new technique to quantify the contribution of the reticular formation to long-latency responses via fMRI Zonnino, A.; Farrens, A. J.; Ress, D.; Sergi, F. 10.1101/582692 — neuroscience — Posted on 2019-03-20 1333 Family saga: reconstructing the evolutionary history of a functionally diverse gene family reveals complexity at the genetic origins of novelty Koludarov, I.; Jackson, T. N.; Pozzi, A.; Mikheyev, A. S. 10.1101/583344 — molecular biology — Posted on 2019-03-20 1334 Cell morphology and nucleoid dynamics in dividing D. radiodurans Floc'h, K.; Lacroix, F.; Servant, P.; Wong, Y.-S.; Kleman, J.-P.; Bourgeois, D.; Timmins, J. 10.1101/582304 — microbiology — Posted on 2019-03-20 1335 Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts Zhou, W.; Nielsen, J. B.; Fritsche, L. G.; LeFaive, J.; Gagliano Taliun, S. A.; Bi, W.; Gabrielsen, M. E.; Daly, M. J.; Neale, B. M.; Hveem, K.; Abecasis, G. R.; Willer, C. J.; Lee, S. 10.1101/583278 — genetics — Posted on 2019-03-20 1336 A transcription factor Abf1 facilitates ORC binding onto the Saccharomyces cerevisiae replication origin via histone acetylase Gcn5 Kohzaki, H.; Murakami, Y. 10.1101/583310 — genetics — Posted on 2019-03-20 1337 Allelopathic effect of Anogeissus pendula Edgew. and Grewia flavescens A.Juss on Desmodium species in Alwar district of Rajasthan Prasad, R.; Yadav, A. S. 10.1101/582023 — ecology — Posted on 2019-03-20 1338 Synonymous SNP: Rare versus frequent codon can cause Phenotypic changes in the human genome SRIVASTAV, A. 10.1101/582213 — bioinformatics — Posted on 2019-03-20 1339 Air mass source determines airborne microbial diversity at the ocean-atmosphere interface of the Great Barrier Reef marine ecosystem Archer, S.; Lee, K.; King-Miaow, K.; Caruso, T.; Harvey, M.; Pointing, S. 10.1101/583427 — microbiology — Posted on 2019-03-20 1340 Tissue Tropism and Transmission Ecology Predict Virulence of Human RNA Viruses Brierley, L.; Pedersen, A. B.; Woolhouse, M. E. J. 10.1101/581512 — epidemiology — Posted on 2019-03-19 1341 ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics Caldas, P.; Lopez-Pelegrin, M.; Pearce, D. J. G.; Budanur, N. B.; Brugues, J.; Loose, M. 10.1101/580944 — biophysics — Posted on 2019-03-19 1342 Functional RNA Structures in the 3’UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses Ochsenreiter, R.; Hofacker, I. L.; Wolfinger, M. T. 10.1101/565580 — bioinformatics — Posted on 2019-03-19 1343 A genetic screen using the Drosophila melanogaster TRiP RNAi collection to identify metabolic enzymes required for eye development Tennessen, J. M.; Pletcher, R. C.; Hardman, S. L.; Intagliata, S. F.; Lawson, R. L.; Page, A. 10.1101/582940 — genetics — Posted on 2019-03-19 1344 Investigation of the validity of two Bayesian ancestral state reconstruction models for estimating Salmonella transmission during outbreaks Bloomfield, S.; Vaughan, T.; Benschop, J.; Marshall, J.; Hayman, D.; Biggs, P.; Carter, P.; French, N. 10.1101/574087 — epidemiology — Posted on 2019-03-19 1345 A topological data analysis based classification method for multiple measurement Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R. 10.1101/569210 — bioinformatics — Posted on 2019-03-19 1346 Translationally Controlled Tumor Protein TCTP as Peptide Vaccine against Schistosoma japonicum: an Immunoinformatics Approach Abdalrahman, R. A.; Ahmed, S. S.; Elnaeem, M. A.; Mohammed, M. S.; Jammie, N. M.; Yousif, I. A.; Mohamed, W. H.; Nasr, S. Y.; Awad-Elkareem, M. A.; Hassan, M. A. 10.1101/466847 — bioinformatics — Posted on 2019-03-19 1347 From skylight input to behavioural output: a computational model of the insect polarised light compass Gkanias, E.; Risse, B.; Mangan, M.; Webb, B. 10.1101/504597 — animal behavior and cognition — Posted on 2019-03-19 1348 The systemin signaling cascade as derived from phosphorylation time courses under stimulation by systemin and its inactive Thr17Ala (A17) analog Hai Ahmad, F.; Wu, X. N.; Stintzi, A.; Schaller, A.; Schulze, W. X. 10.1101/535070 — plant biology — Posted on 2019-03-19 1349 NMDA receptors enhance the fidelity of synaptic integration Li, C.; Baker, A. L.; Gulledge, A. T. 10.1101/566117 — neuroscience — Posted on 2019-03-19 1350 Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders Mondo, E.; Barone, M.; Soverini, M.; D'Amico, F.; Cocchi, M.; Petrulli, C.; Mattioli, M.; Marliani, G.; Candela, M.; Accorsi, P. A. 10.1101/573865 — microbiology — Posted on 2019-03-19 1351 On the cross-population portability of gene expression prediction models Keys, K. L.; Mak, A. C. Y.; White, M. J.; Eckalbar, W.; Dahl, A. W.; Mefford, J.; Mikhaylova, A. V.; Contreras, M. G.; Elhawary, J. R.; Eng, C.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Lenoir, M. A.; Ye, C. J.; Thornton, T. A.; Zaitlen, N.; Burchard, E. G.; Gignoux, C. R. 10.1101/552042 — genomics — Posted on 2019-03-19 1352 Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight novel adipocyte biology Tanigawa, Y.; Li, J.; Justesen, J. M.; Horn, H.; Aguirre, M.; DeBoever, C.; Chang, C.; Narasimhan, B.; Lage, K.; Hastie, T. J.; Park, C. Y.; Bejerano, G.; Ingelsson, E.; Rivas, M. 10.1101/442715 — genetics — Posted on 2019-03-19 1353 Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors Cerquone Perpetuini, A.; Reggio, A.; Cerretani, M.; Giuliani, G.; Santoriello, M.; Stefanelli, R.; Palma, A.; Harper, S.; Castagnoli, L.; Bresciani, A.; Cesareni, G. 10.1101/581363 — cell biology — Posted on 2019-03-19 1354 Life history recorded in the vagino-cervical microbiome Jie, Z.; Chen, C.; Hao, L.; Li, F.; Tian, L.; Tong, X.; Song, L.; Cai, K.; Yu, X.; Li, Y.; Rao, W.; Liao, Y.; Zhou, D.; Qiu, X.; Chen, X.; Zi, J.; Liu, N.; Zhang, W.; Liu, X.; Xiao, L.; Xu, X.; Yang, H.; Wang, J.; Hou, Y.; Kristiansen, K.; Jia, H. 10.1101/533588 — microbiology — Posted on 2019-03-19 1355 In vivo identification of GTPase interactors by mitochondrial relocalization and proximity biotinylation Munro, S.; Gillingham, A. K.; Bertram, J.; Begum, F. 10.1101/553206 — cell biology — Posted on 2019-03-19 1356 Caterpillars on a phytochemical landscape Forister, M. L.; Yoon, S.; Philbin, C. S.; Dodson, C. D.; Hart, B.; Harrison, J. G.; Shelef, O.; Fordyce, J. A.; Marion, Z. H.; Nice, C. C.; Richards, L. A.; Buerkle, C. A.; Gompert, Z. 10.1101/498139 — ecology — Posted on 2019-03-19 1357 Cell confinement reveals a branched-actin independent circuit for neutrophil polarity Graziano, B. R.; Town, J. P.; Nagy, T. L.; Fosnaric, M.; Penic, S.; Iglic, A.; Kralj-Iglic, V.; Gov, N.; Diz-Munoz, A.; Weiner, O. D. 10.1101/457119 — cell biology — Posted on 2019-03-19 1358 Interactions of nuclear transport factors and surface-conjugated FG nucleoporins: Insights and limitations Hayama, R.; Sorci, M.; Keating, J. J.; Hecht, L. M.; Plawsky, J. L.; Belfort, G.; Chait, B. T.; Rout, M. P. 10.1101/435651 — biophysics — Posted on 2019-03-19 1359 Effect of temperature and photoperiod on survival and biomarkers of senescence in common woodlouse DEPEUX, C.; SAMBA-LOUAKA, A.; BRAQUART-VARNIER, C.; MOREAU, J.; LEMAITRE, J.-F.; LAVERRE, T.; PAULHAC, H.; DECHAUME-MONCHARMONT, F.-X.; GAILLARD, J.-M.; BELTRAN-BECH, S. 10.1101/433011 — evolutionary biology — Posted on 2019-03-19 1360 Stimulus-responsive self-assembly of protein-based fractals by computational design Hernandez, N.; Hansen, W.; Zhu, D.; Shea, M.; Khalid, M.; Manichev, V.; Putnis, M.; Chen, M.; Dodge, A.; Yang, L.; Banal, M.; Gustaffson, T.; Feldman, L.; Lee, S.-H.; Wackett, L.; Dai, W.; Khare, S. 10.1101/274183 — biophysics — Posted on 2019-03-19 1361 A transformation of oxygen saturation (the saturation virtual shunt) to improve clinical prediction model calibration and interpretation Zhou, G.; Karlen, W.; Brant, R.; Wiens, M.; Kissoon, N.; Ansermino, J. M. 10.1101/391292 — bioengineering — Posted on 2019-03-19 1362 Evolution transforms pushed waves into pulled waves Erm, P.; Phillips, B. L. 10.1101/266007 — ecology — Posted on 2019-03-19 1363 Intrinsic Disorder and Degeneracy in Molecular Scale Organization of Biological Membrane Iyer, S. S.; Srivastava, A. 10.1101/582338 — biophysics — Posted on 2019-03-19 1364 The dynamics of centromere motion through the metaphase-to-anaphase transition reveal a centromere separation order Armond, J. W.; Dale, K. L.; Burroughs, N. J.; McAinsh, A. D.; Vladimirou, E. 10.1101/582379 — cell biology — Posted on 2019-03-19 1365 ITGA2 is a target of miR-206 promoting cancer stemness and lung metastasis through enhanced ACLY and CCND1 expression in triple negative breast cancer Adorno-Cruz, V.; Hoffmann, A. D.; Liu, X.; Wray, B.; Keri, R. A.; Liu, H. 10.1101/583062 — cancer biology — Posted on 2019-03-19 1366 Septate junctions regulate gut homeostasis through regulation of stem cell proliferation and enterocyte behavior in Drosophila Izumi, Y.; Furuse, K.; Furuse, M. 10.1101/582148 — cell biology — Posted on 2019-03-19 1367 Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis Bosmani, C.; Bach, F.; Leuba, F.; Hanna, N.; Burdet, F.; Pagni, M.; Hagedorn, M.; Soldati, T. 10.1101/582049 — cell biology — Posted on 2019-03-19 1368 Continuous dynamic modeling of regulated cell adhesion Ko, J. M.; Lobo, D. 10.1101/582429 — biophysics — Posted on 2019-03-19 1369 Geographic variation in reproductive assurance of Clarkia pulchella Bontrager, M.; Muir, C. D.; Angert, A. 10.1101/372375 — ecology — Posted on 2019-03-19 1370 A Systematic Evaluation of Single Cell RNA-Seq Analysis Pipelines Vieth, B.; Parekh, S.; Ziegenhain, C.; Enard, W.; Hellmann, I. 10.1101/583013 — bioinformatics — Posted on 2019-03-19 1371 ganon: continuously up-to-date with database growth for precise short read classification in metagenomics Piro, V. C.; Dadi, T. H.; Seiler, E.; Reinert, K.; Renard, B. Y. 10.1101/406017 — bioinformatics — Posted on 2019-03-19 1372 HaploBlocker: Creation of subgroup specific haplotype blocks and libraries Pook, T.; Schlather, M.; de los Campos, G.; Mayer, M.; Schoen, C. C.; Simianer, H. 10.1101/339788 — genetics — Posted on 2019-03-19 1373 Ndr/Lats kinases bind specific Mob-family coactivators through a conserved and modular interface Parker, B.; Gogl, G.; Balint, M.; Hetenyi, C.; Remenyi, A.; Weiss, E. 10.1101/242115 — biochemistry — Posted on 2019-03-19 1374 The human proteome co-regulation map reveals functional relationships between proteins Kustatscher, G.; Grabowski, P.; Schrader, T.; Passmore, J. B.; Schrader, M.; Rappsilber, J. 10.1101/582247 — systems biology — Posted on 2019-03-19 1375 Sodium nitroprusside prevents the detrimental effects of glucose on the neurovascular unit and behaviour in zebrafish Chhabria, K.; Vouros, A.; Gray, C.; MacDonald, R. B.; Jiang, Z.; Wilkinson, R. N.; Plant, K.; Vasilaki, E.; Howarth, C.; Chico, T. 10.1101/576942 — neuroscience — Posted on 2019-03-19 1376 Short-term effects of sound localization training in virtual reality Steadman, M. A.; Kim, C.; Lestang, J.-H.; Goodman, D. F. M.; Picinali, L. 10.1101/207753 — neuroscience — Posted on 2019-03-19 1377 Direct visualization of single nuclear pore complex proteins using genetically-encoded probes for DNA-PAINT Schlichthaerle, T.; Strauss, M. T.; Schueder, F.; Auer, A.; Nijmeijer, B.; Kueblbeck, M.; Jimenez Sabinina, V.; Ries, J.; Ellenberg, J.; Jungmann, R. 10.1101/579961 — cell biology — Posted on 2019-03-19 1378 Multi-omics profiling establishes the polypharmacology of FDA Approved CDK4/6 inhibitors and the potential for differential clinical activity Hafner, M.; Mills, C. E.; Subramanian, K.; Chen, C.; Chung, M.; Boswell, S. A.; Everley, R. A.; Liu, C.; Walmsley, C. S.; Juric, D.; Sorger, P. 10.1101/211680 — cancer biology — Posted on 2019-03-19 1379 Post-transcriptional mechanisms distinguish human and chimp forebrain progenitor cells Grassi, D.; Brattaas, P. L.; Valdes, J. G.; Rezeli, M.; Jonsson, M. E.; Nolbrant, S.; Parmar, M.; Marko-Varga, G.; Jakobsson, J. 10.1101/582197 — neuroscience — Posted on 2019-03-19 1380 A stable pollination environment limits current but not potential evolution of floral traits Castellanos, M. C.; Montero-Pau, J.; Ziarsolo, P.; Blanca, J. M.; Canizares, J.; Pausas, J. G. 10.1101/581827 — evolutionary biology — Posted on 2019-03-19 1381 Integrative network modeling reveals mechanisms underlying T cell exhaustion Bolouri, H.; Young, M.; Beilke, J.; Johnson, R.; Fox, B.; Huang, L.; Costa Santini, C.; Hill, C. M.; van der Vuurst de Vries, A.-R.; Shannon, P.; Dervan, A.; Sivakumar, P.; Trotter, M.; Bassett, D.; Ratushny, A. 10.1101/582312 — systems biology — Posted on 2019-03-19 1382 crAssphage abundance and genomic selective pressure correlate with altered bacterial abundance in the fecal microbiota of South African mother-infant dyads Brown, B. P.; Wendoh, J.; Chopera, D.; Havyarimana, E.; Jaumdally, S. Z.; Nyangahu, D. D.; Gray, C.; Martin, D. P.; Varsani, A.; Jaspan, H. B. 10.1101/582015 — microbiology — Posted on 2019-03-19 1383 Cross-transmission is not the source of new Mycobacteirum abscessus infections in a multi-centre cohort of cystic fibrosis patients Doyle, R. M.; Rubio, M.; Dixon, G.; Hartley, J.; Klein, N.; Coll, P.; Harris, K. A. 10.1101/582684 — microbiology — Posted on 2019-03-19 1384 A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression Burgess, S. T.; Marr, E. J.; Bartley, K.; Nunn, F. G.; Down, R. E.; Weaver, R. J.; Prickett, J. C.; Dunn, J.; Rombauts, S.; Van Leeuwen, T.; Van de Peer, Y.; Nisbet, A. J. 10.1101/578120 — genomics — Posted on 2019-03-19 1385 On triangular inequalities of correlation-based distances for gene expression profiles Jiaxing, C.; Ng, Y. K.; Lin, L.; Jiang, Y.; Li, S. 10.1101/582106 — bioinformatics — Posted on 2019-03-19 1386 Analysis of Genetically Regulated Gene Expression identifies a trauma type specific PTSD gene, SNRNP35 Huckins, L. M.; Breen, M. S.; Chatzinakos, C.; Hartmann, J.; Klengel, T.; da Silva Almeida, A. C.; Dobbyn, A.; Girdhar, K.; Hoffman, G. E.; Klengel, C.; Logue, M.; Lori, A.; Morrison, F. G.; Nguyen, H. T.; Park, Y.; Ruderfer, D.; Sloofman, L.; van Rooij, S. J.; PTSD Working Group of the Psychiatric Genomics Con, ; Baker, D.; Chen, C.-Y.; Cox, N.; Duncan, L.; Geyer, M. A.; Glatt, S.; Im, H. K.; Maihofer, A.; Risbrough, V. B.; Smoller, J. W.; Stein, D. J.; Yehuda, R.; Liberzon, I.; Koenen, K. C.; Jovanovic, T.; Kellis, M.; Miller, M. W.; Bacanu, S.-A.; Nievergelt, C.; Buxbaum, J. D.; Sklar, P.; 10.1101/581124 — genetics — Posted on 2019-03-19 1387 Butterfly assemblages from Amazonian flooded forests are not more species-poor than from unflooded forests Rabelo, R. M.; Magnusson, W. E. 10.1101/582742 — ecology — Posted on 2019-03-19 1388 The spindle assembly checkpoint functions during early development in non-chordate embryos. Chenevert, J.; Roca, M.; Besnardeau, L.; Ruggiero, A.; Nabi, D.; McDougall, A.; Copley, R. R.; Christians, E.; Castagnetti, S. 10.1101/582759 — cell biology — Posted on 2019-03-19 1389 LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena Jiang, Y.-Y.; Maier, W.; Baumeister, R.; Minevich, G.; Joachimiak, E.; Wloga, D.; Ruan, Z.; Kannan, N.; Bocarro, S.; Bahraini, A.; Vasudevan, K. K.; Lechtreck, K.; Orias, E.; Gaertig, J. 10.1101/582833 — cell biology — Posted on 2019-03-19 1390 Towards a fully automated surveillance of well-being status in laboratory mice using deep learning Andresen, N.; Wöllhaf, M.; Hohlbaum, K.; Lewejohann, L.; Hellwich, O.; Thöne-Reineke, C.; Belik, V. 10.1101/582817 — animal behavior and cognition — Posted on 2019-03-19 1391 A quantitative modular modeling approach reveals the consequences of different A20 feedback implementations for the NF-kB signaling dynamics Mothes, J.; Ipenberg, I.; Arslan, S. C.; Benary, U.; Scheidereit, C.; Wolf, J. 10.1101/582767 — systems biology — Posted on 2019-03-19 1392 An event-related potential study of decision making and feedback utilization in female college students who binge drink Na, E.-C.; Jang, K.-M.; Kim, M.-S. 10.1101/582734 — neuroscience — Posted on 2019-03-19 1393 Relation of seasonal birth pulses and maternal immunity with viral invasion and persistence: A case study of Hendra virus infection in a population of black flying foxes (Pteropus alecto) Jeong, J.; Peel, A. J.; Plowright, R. K.; Restif, O.; McCallum, H. 10.1101/582726 — epidemiology — Posted on 2019-03-19 1394 Novel insights into the morphology of Plesiochelys bigleri from the early Kimmeridgian of Northwestern Switzerland Burek - Raselli, I. J.; Anquetin, J. 10.1101/582700 — paleontology — Posted on 2019-03-19 1395 Ribosome profiling at isoform level reveals an evolutionary conserved impact of differential splicing on the proteome Reixachs-Sole, M.; Ruiz-Orera, J.; Alba, M.; Eyras, E. 10.1101/582031 — genomics — Posted on 2019-03-19 1396 Determinants of transcription factor regulatory range Chen, C.-H.; Zheng, R.; Fan, J.; Brown, M.; Liu, J. S.; Meyer, C. A.; Liu, X. S. 10.1101/582270 — genomics — Posted on 2019-03-19 1397 Droplet scRNA-seq is not zero-inflated Svensson, V. 10.1101/582064 — bioinformatics — Posted on 2019-03-19 1398 REMI-seq: Development of methods and resources for functional genomics in Dictyostelium Gruenheit, N.; Baldwin, A.; Stewart, B.; Jaques, S.; Keller, T.; Parkinson, K.; Chisholm, R.; Harwood, A.; Thompson, C. 10.1101/582072 — genomics — Posted on 2019-03-19 1399 An ATAC-seq atlas of chromatin accessibility in mouse tissues Liu, C.; Wang, M.; Wei, X.; Wu, L.; Xu, J.; Dai, X.; Xia, J.; Cheng, M.; Yuan, Y.; Zhang, P.; Li, J.; Feng, T.; Chen, A.; Zhang, W.; Chen, F.; Shang, Z.; Zhang, X.; Peters, B. A.; Liu, L. 10.1101/582171 — genomics — Posted on 2019-03-19 1400 Coronary atherosclerosis: Un-altered physiology de Groot, P.; Veldhuizen, R. W. 10.1101/581454 — pathology — Posted on 2019-03-19 1401 The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3 Kuang, Z.; Wang, Y.; Li, Y.; Ye, C.; Ruhn, K. A.; Behrendt, C. L.; Olson, E. N.; Hooper, L. V. 10.1101/580613 — microbiology — Posted on 2019-03-19 1402 Tissue Tropism and Transmission Ecology Predict Virulence of Human RNA Viruses Brierley, L.; Pedersen, A. B.; Woolhouse, M. E. J. 10.1101/581512 — epidemiology — Posted on 2019-03-19 1403 Differences in proteome response to cold acclimation in Zoysia japonica cultivars with different levels of freeze tolerance Brown, J. M.; Holloway, M. P.; Dacosta, M. A.; Bernstein, R. P.; Lu, J. H.; Tuong, T. D.; Patton, A. J.; Dunne, J. C.; Arellano, C.; Livingston, D. P.; Milla-Lewis, S. R. 10.1101/581488 — physiology — Posted on 2019-03-19 1404 Transitions in brain-network level information processing dynamics are driven by alterations in neural gain Li, M.; Han, Y.; Aburn, M. J.; Breakspear, M.; Poldrack, R. A.; Shine, J. M.; Lizier, J. T. 10.1101/581538 — neuroscience — Posted on 2019-03-19 1405 Inter-individual genomic heterogeneity within European population isolates Anagnostou, P.; Dominici, V.; Battaggia, C.; Sarno, S.; Boattini, A.; Calo, C.; Francalacci, P.; Vona, G.; Tofanelli, S.; Vilar, M.; Colonna, V.; Pagani, L.; Destro Bisol, G. 10.1101/581470 — genomics — Posted on 2019-03-19 1406 DNA methylation, microRNA expression profiles and their relationships with transcriptome in grass-fed and grain-fed Angus Cattle rumen tissue Li, Y.; Carrillo, J. A.; Ding, Y.; He, Y.; Zhao, C.; Liu, J.; Zan, L.; Song, J. 10.1101/581421 — genomics — Posted on 2019-03-19 1407 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron: Hippocampal SOM interneurons, mTORC1 and memory Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C. 10.1101/580670 — neuroscience — Posted on 2019-03-19 1408 Greater neurodegeneration and behavioral deficits after single closed head traumatic brain injury in adolescent vs adult mice Guilhaume-Correa, F.; Cansler, S. M.; Shalosky, E. M.; Goodman, M. D.; Evanson, N. K. 10.1101/577999 — neuroscience — Posted on 2019-03-19 1409 Vps34/PIK3C3 deletion in thyroid impairs thyroid hormonogenesis and autophagic flux Grieco, G.; Wang, T.; Delcorte, O.; Janssens, V.; Spourquet, C.; Strickaert, A.; Gaide Chevronnay, H. P.; Liao, X.-H.; Bilanges, B.; Refetoff, S.; Vanhaesebroeck, B.; Maenhaut, C.; Courtoy, P. J.; Pierreux, C. E. 10.1101/580142 — cell biology — Posted on 2019-03-19 1410 LNISKS: Reference-free mutation identification for large and complex crop genomes Suchecki, R.; Sandhu, A.; Deschamps, S.; Llaca, V.; Wolters, P.; Watson-Haigh, N.; Pallotta, M.; Whitford, R.; Baumann, U. 10.1101/580829 — bioinformatics — Posted on 2019-03-19 1411 Reconstruction and Analysis of a Kluyveromyces marxianus Genome-scale Metabolic Model Marcisauskas, S.; Ji, B.; Nielsen, J. 10.1101/581587 — systems biology — Posted on 2019-03-19 1412 Biofilm-dependent evolutionary pathways to antibiotic resistance Santos-Lopez, A.; Marshall, C. W.; Scribner, M. R.; Snyder, D.; Cooper, V. S. 10.1101/581611 — microbiology — Posted on 2019-03-19 1413 Overlapping transcriptional expression response of wheat zinc-induced facilitator-like transporters emphasize important role during Fe and Zn stress Sharma, S.; Kaur, G.; Kumar, A.; Kaur, J.; Pandey, A. K. 10.1101/581405 — plant biology — Posted on 2019-03-19 1414 Corticolimbic circuit structure moderates an association between early life stress and later trait anxiety Kim, M. J.; Farber, M. J.; Knodt, A. R.; Hariri, A. R. 10.1101/581926 — neuroscience — Posted on 2019-03-19 1415 Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain Lei, M.; Tempel, W.; Liu, K.; Min, J. 10.1101/581934 — biochemistry — Posted on 2019-03-18 1416 Exploring the extracellular regulation of the tumor angiogenic interaction network using a systems biology model Li, D.; Finley, S. D. 10.1101/581884 — systems biology — Posted on 2019-03-18 1417 Presynaptic boutons that contain mitochondria are more stable Lees, R. M.; Johnson, J. D.; Ashby, M. C. 10.1101/580530 — neuroscience — Posted on 2019-03-18 1418 Stag1 and Stag2 regulate cell fate decisions in hematopoiesis through non-redundant topological control Viny, A. D.; Bowman, R. L.; Liu, Y.; Lavallee, V.-P.; Redlich, S. E.; Xiao, W.; Durham, B. H.; Navitski, A.; Park, J.; Braunstein, S.; Azizi, E.; Witkin, M.; Baslan, T.; Ott, C. J.; Pe'er, D.; Dekker, J.; Koche, R.; Levine, R. L. 10.1101/581868 — cell biology — Posted on 2019-03-18 1419 Graphene nanoflakes for acute manipulation of membrane cholesterol and transmembrane signaling Kitko, K. E.; Hong, T.; Lazarenko, R. M.; Montenegro-Burke, R. J.; Shah, A. T.; Zhang, Y.; Raghunathan, K.; Kenworthy, A. K.; Skala, M. C.; McLean, J. A.; Xu, Y.-Q.; Zhang, Q. 10.1101/581942 — cell biology — Posted on 2019-03-18 1420 The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils Prajsnar, T. K.; Serba, J. J.; Dekker, B. M.; Gibson, J. F.; Masud, S.; Fleming, A.; Johnston, S. A.; Renshaw, S. A.; Meijer, A. H. 10.1101/581223 — immunology — Posted on 2019-03-18 1421 Absolute and relative pitch processing in the human brain: Neural and behavioral evidence Leipold, S.; Brauchli, C.; Greber, M.; Jaencke, L. 10.1101/526541 — neuroscience — Posted on 2019-03-18 1422 Dynamics of genomic change during evolutionary rescue in the seed beetle Callosobruchus maculatus Rego, A.; Messina, F. J.; Gompert, Z. 10.1101/364158 — evolutionary biology — Posted on 2019-03-18 1423 Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons Haq, N.; Schmidt-Hieber, C.; Sialana, F. J.; Ciani, L.; Heller, J. P.; Stewart, M.; Bentley, L.; Wells, S.; Rodenburg, R. J.; Nolan, P. M.; Forsythe, E.; Wu, M. C.; Lubec, G.; Hausser, M.; Beales, P.; Christou-Savina, S. 10.1101/580399 — cell biology — Posted on 2019-03-18 1424 Nicotinamide Deficiency In Primary Open-Angle Glaucoma Kouassi Nzoughet, J.; Chao de la Barca, J. M.; Guehlouz, K.; Leruez, S.; Coulbault, L.; Allouche, S.; Bocca, C.; Muller, J.; Amati-Bonneau, P.; Gohier, P.; Bonneau, D.; Simard, G.; Milea, D.; Lenaers, G.; Procaccio, V.; Reynier, P. 10.1101/571638 — biochemistry — Posted on 2019-03-18 1425 Systems-level network modeling of Small Cell Lung Cancer subtypes identifies master regulators and destabilizers Wooten, D. J.; Maddox, S. F.; Tyson, D.; Liu, Q.; Lim, J. S.; Sage, J.; Lopez, C.; Quaranta, V. 10.1101/506402 — systems biology — Posted on 2019-03-18 1426 Sodium-powered stators of the bacterial flagellar motor can generate torque in the presence of phenamil with mutations near the peptidoglycan-binding region. Ishida, T.; Ito, R.; Clark, J.; Matzke, N. J.; Sowa, Y.; Baker, M. A. 10.1101/507533 — microbiology — Posted on 2019-03-18 1427 A map of climate change-driven natural selection in Arabidopsis thaliana Exposito-Alonso, M.; Burbano, H. A.; Bossdorf, O.; Nielsen, R.; Weigel, D. 10.1101/321133 — evolutionary biology — Posted on 2019-03-18 1428 Macrophage Activation by a Substituted PyrimidoIndole Increases Anti-Cancer Activity Hardie, J.; Mas-Rosario, J. A.; Ha, S.; Rizzo, E. M.; Farkas, M. E. 10.1101/581710 — pharmacology and toxicology — Posted on 2019-03-18 1429 LRRK2 modifies α-syn pathology and spread in mouse models and human neurons Bieri, G.; Brahic, M.; Bousset, L.; Couthouis, J.; Kramer, N.; Ma, R.; Nakayama, L.; Monbureau, M.; Defensor, E.; Schuele, B.; Shamloo, M.; Melki, R.; Gitler, A. D. 10.1101/522086 — neuroscience — Posted on 2019-03-18 1430 Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for incidence surveillance Sempa, J. B.; Welte, A.; Busch, M. P.; Hall, J.; Hampton, D.; Keating, S. M.; Facente, S. N.; Marson, K.; Parkin, N.; Pilcher, C. D.; Murphy, G.; Grebe, E. 10.1101/572677 — epidemiology — Posted on 2019-03-18 1431 The mouse HP1 proteins are essential for preventing liver tumorigenesis Saksouk, N.; Hajdari, S.; Pratlong, M.; Barrachina, C.; Zavoriti, A.; Sarrazin, A.; Pirot, N.; Noël, J.-Y.; Khellaf, L.; Fabbrizio, E.; Julien, E.; Cammas, F. M. 10.1101/441279 — cancer biology — Posted on 2019-03-18 1432 GraphClust2: annotation and discovery of structured RNAs with scalable and accessible integrative clustering Miladi, M.; Sokhoyan, E.; Houwaart, T.; Heyne, S.; Costa, F.; Gruening, B.; Backofen, R. 10.1101/550335 — bioinformatics — Posted on 2019-03-18 1433 ProtCID: A tool for hypothesis generation of the structures of protein interactions Xu, Q.; Dunbrack, R. L. 10.1101/579862 — bioinformatics — Posted on 2019-03-18 1434 Optimal control of acute myeloid leukaemia Sharp, J.; Browning, A.; Mapder, T.; Burrage, K.; Simpson, M. 10.1101/429811 — synthetic biology — Posted on 2019-03-18 1435 Large-scale correlations between eight key double strand break related data sets over the whole human genome Brahme, A.; Hulten, M.; Bengtsson, C.; Hultgren, A.; Zetterberg, A. 10.1101/581173 — genomics — Posted on 2019-03-18 1436 Population structure across scales facilitates coexistence and spatial heterogeneity of antibiotic-resistant infections Krieger, M. S.; Nowak, M. A.; Hill, A. L. 10.1101/469171 — epidemiology — Posted on 2019-03-18 1437 Microtubules Regulate Spatial Localization and Availability of Insulin Granules in Pancreatic Beta Cells. Bracey, K. M.; Ho, K.-H.; Yampolsky, D.; Gu, G.; Kaverina, I.; Holmes, W. 10.1101/581330 — cell biology — Posted on 2019-03-18 1438 Live detection of neural stem and glioblastoma cells by an oligothiophene derivative Ilkhanizadeh, S.; Gracias, A.; Aslund, A. K.; Back, M.; Simon, R.; Rraklli, V.; Migliori, B.; Kavanagh, E.; Nelander, S.; Westermark, B.; Uhrbom, L.; Forsberg-Nilsson, K.; Teixeira, A. I.; Konradsson, P.; Uhlen, P.; Joseph, B.; Hermanson, O.; Nilsson, P. R. 10.1101/579185 — bioengineering — Posted on 2019-03-18 1439 Evolving optimum camouflage with Generative Adversarial Networks Talas, L.; Fennell, J. G.; Kjernsmo, K.; Cuthill, I. C.; Scott-Samuel, N. E.; Baddeley, R. J. 10.1101/429092 — animal behavior and cognition — Posted on 2019-03-18 1440 Chrysin, but not the flavone backbone, decreases anxiety-like behavior in animal tests Ponciano, L. J.; Costa, B. P.; Feitosa, L. M.; Campos, K. S.; Chaves, S. N.; Cueto-Escobedo, J.; Lima-Maximino, M. G.; Rodriguez-Landa, J. F.; Maximino, C. 10.1101/575514 — pharmacology and toxicology — Posted on 2019-03-18 1441 Single cell multi-omics analysis reveals novel roles for DNA methylation in sensory neuron injury responses Hu, Y.; An, Q.; Fan, G. 10.1101/572446 — neuroscience — Posted on 2019-03-18 1442 Hybrid genome assembly and annotation of Danionella translucida Kadobianskyi, M.; Schulze, L.; Schuelke, M.; Judkewitz, B. 10.1101/539692 — genomics — Posted on 2019-03-18 1443 Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression Hafemeister, C.; Satija, R. 10.1101/576827 — genomics — Posted on 2019-03-18 1444 The relationship of body condition, superoxide dismutase and superoxide with sperm performance Friesen, C.; de Graaf, S. P.; Olsson, M. 10.1101/556548 — evolutionary biology — Posted on 2019-03-18 1445 Distinct characteristics of genes associated with phenome-wide variation in maize (Zea mays) Liang, Z.; Qiu, Y.; Schnable, J. 10.1101/534503 — bioinformatics — Posted on 2019-03-18 1446 Probing Neural Networks for Dynamic Switches of Communication Pathways Finger, H.; Gast, R.; Gerloff, C.; Engel, A. K.; König, P. 10.1101/523522 — neuroscience — Posted on 2019-03-18 1447 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R. 10.1101/564617 — neuroscience — Posted on 2019-03-18 1448 The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders Miller-Rhodes, P.; Kong, C.; Baht, G. S.; Rodriguiz, R. M.; Wetsel, W. C.; Gelbard, H. A.; Terrando, N. 10.1101/537472 — neuroscience — Posted on 2019-03-18 1449 The correlated state in balanced neuronal networks Baker, C.; Ebsch, C.; Lampl, I.; Rosenbaum, R. 10.1101/372607 — neuroscience — Posted on 2019-03-18 1450 Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism Thompson, M. G.; Blake-Hedges, J. M.; Cruz-Morales, P.; Barajas, J. F.; Curran, S. C.; Eiben, C. B.; Harris, N. C.; Benites, V. T.; Gin, J. W.; Sharpless, W. A.; Twigg, F. F.; Skyrud, W.; Krishna, R. N.; Pereira, J. H.; Baidoo, E.; Petzold, C. J.; Adams, P. D.; Arkin, A. P.; Deutschbauer, A. M.; Keasling, J. D. 10.1101/450254 — microbiology — Posted on 2019-03-18 1451 Dominant coral bacterium Endozoicomonas acroporae metabolizes Dimethylsulfoniopropionate Tandon, K.; Chiang, P.-W.; Lu, C.-Y.; Yang, S.-H.; Chan, Y.-F.; Wada, N.; Chen, P.-Y.; Chang, H.-Y.; Chou, M.-S.; Chen, W.-M.; Tang, S.-L. 10.1101/519546 — ecology — Posted on 2019-03-18 1452 An autonomous oscillator times and executes centriole biogenesis Aydogan, M. G.; Steinacker, T. L.; Mofatteh, M.; Gartenmann, L.; Wainman, A.; Saurya, S.; Wong, S. S.; Zhou, F. Y.; Boemo, M. A.; Raff, J. W. 10.1101/510875 — cell biology — Posted on 2019-03-18 1453 Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors Cerquone Perpetuini, A.; Reggio, A.; Cerretani, M.; Giuliani, G.; Santoriello, M.; Stefanelli, R.; Palma, A.; Harper, S.; Castagnoli, L.; Bresciani, A.; Cesareni, G. 10.1101/581363 — cell biology — Posted on 2019-03-18 1454 Multiplatform Biomarker Identification using a Data-driven Approach Enables Single-sample Classification Zhang, L.; Thapa, I.; Haas, C.; Bastola, D. 10.1101/581686 — bioinformatics — Posted on 2019-03-18 1455 Isolating the key factors defining the magnitude of hippocampal neurogenesis’ effects on anxiety, memory and pattern separation Franca, T. F. A. 10.1101/563023 — neuroscience — Posted on 2019-03-18 1456 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov. Studholme, D. J.; Wicker, E.; Aspin, A.; Bogdanove, A.; Broders, K.; Dubrow, Z.; Grant, M.; Jones, J. B.; Karamura, G.; Lang, J.; Leach, J.; Abrare, S. M.; Mahuku, G.; Nakato, G. V.; Coutinho, T.; Smith, J.; Bull, C. 10.1101/571166 — microbiology — Posted on 2019-03-18 1457 Alveolar macrophages up-regulate a non-classical innate response to Mycobacterium tuberculosis infection in vivo Rothchild, A. C.; Olson, G. S.; Nemeth, J.; Amon, L. M.; Mai, D.; Gold, E. S.; Diercks, A. H.; Aderem, A. 10.1101/520791 — immunology — Posted on 2019-03-18 1458 Optimising colour for camouflage and visibility using deep learning: the effects of the environment and the observer’s visual system Fennell, J.; Talas, L.; Baddeley, R.; Cuthill, I.; Scott-Samuel, N. 10.1101/428193 — animal behavior and cognition — Posted on 2019-03-18 1459 Limits on visual awareness of object targets in the context of other object category masks: Investigating bottlenecks in the continuous flash suppression paradigm with hand and tool stimuli Zopf, R.; Schweinberger, S. R.; Rich, A. N. 10.1101/363515 — neuroscience — Posted on 2019-03-18 1460 CRUMBLER: A tool for the Prediction of Ancestry in Cattle Crum, T. E.; Schnabel, R. D.; Decker, J. E.; Regitano, L. C.; Taylor, J. F. 10.1101/396341 — genomics — Posted on 2019-03-18 1461 Promoter-anchored chromatin interactions predicted from genetic analysis of epigenomic data Wu, Y.; Qi, T.; Wang, H.; Zhang, F.; Zheng, Z.; Phillips-Cremins, J. E.; Deary, I. J.; McRae, A. F.; Wray, N. R.; Zeng, J.; Yang, J. 10.1101/580993 — genetics — Posted on 2019-03-18 1462 Interpreting HIV Diagnostic Histories into Infection Time Estimates: Analytical Framework and Online Tool Grebe, E.; Facente, S. N.; Bingham, J.; Pilcher, C. D.; Powrie, A.; Gerber, J.; Priede, G.; Chibawara, T.; Busch, M. P.; Murphy, G.; Kassanjee, R.; Welte, A. 10.1101/323808 — epidemiology — Posted on 2019-03-18 1463 Improving management strategies of plant diseases using sequential sensitivity analyses Rimbaud, L.; Dallot, S.; Bruchou, C.; Thoyer, S.; Jacquot, E.; Soubeyrand, S.; Thebaud, G. 10.1101/315747 — epidemiology — Posted on 2019-03-18 1464 Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress Chakraborty, D.; Felzen, V.; Hiebel, C.; Stuerner, E.; Perumal, N.; Manicam, C.; Sehn, E.; Grus, F.; Wolfrum, U.; Behl, C. 10.1101/580977 — cell biology — Posted on 2019-03-18 1465 Differential gene expression and gene-set enrichment analysis in Caco-2 monolayers during a 35-day timeline with Dexamethasone exposure. Robinson, J.; Turkington, S.; Abey, S.; Kenea, N.; Henderson, W. 10.1101/355552 — cell biology — Posted on 2019-03-18 1466 Determining the Hierarchical Architecture of the Human Brain Using Subject-Level Clustering of Functional Networks Akiki, T. J.; Abdallah, C. G. 10.1101/350462 — neuroscience — Posted on 2019-03-18 1467 Statistical context dictates the relationship between feedback-related EEG signals and learning Nassar, M.; Bruckner, R.; Frank, M. J. 10.1101/581744 — neuroscience — Posted on 2019-03-18 1468 Immune profiling in M. tuberculosis infection enables stratification of patients with active disease Duffy, D.; Nemes, E.; Llibre, A.; Rouilly, V.; Filander, E.; Africa, H.; Mabwe, S.; Jaxa, L.; Charbit, B.; Musvosvi, M.; Mulenga, H.; The Milieu Interieur Consortium, ; Thomas, S.; Hatherill, M.; Bilek, N.; Scriba, T. J.; Albert, M. L. 10.1101/581298 — immunology — Posted on 2019-03-18 1469 Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments Gresham, D.; Bonneau, R.; Jackson, C. A.; Castro, D. M.; Saldi, G.-A. 10.1101/581678 — genomics — Posted on 2019-03-18 1470 Generalists versus specialists in fluctuating environments: a bet-hedging perspective Haaland, T. R.; Wright, J.; Ratikainen, I. I. 10.1101/581371 — evolutionary biology — Posted on 2019-03-18 1471 Transient non-integrative nuclear reprogramming promotes multifaceted reversal of aging in human cells Sarkar, T. J.; Quarta, M.; Mukherjee, S.; Colville, A.; Paine, P.; Doan, L.; Tran, C. M.; Chu, C. R.; Horvath, S.; Bhutani, N.; Rando, T. A.; Sebastiano, V. 10.1101/573386 — cell biology — Posted on 2019-03-18 1472 Insight into dynamics of APOBEC3G protein in complexes with DNA assessed by high speed AFM Pan, Y.; Shlyakhtenko, L.; Lyubchenko, Y. 10.1101/581793 — biophysics — Posted on 2019-03-18 1473 Rational nanotoolbox with theranostic potential for medicated pro-regenerative corneal implants Patra, H. K.; Azharuddin, M.; Islam, M. M.; Papapavlou, G.; Deb, S.; Zhu, G. H.; Romu, T.; Dhara, A. K.; Jafari, M. J.; Gadheri, A.; Hinkula, J.; Rajan, M. S.; Slater, N. 10.1101/581090 — biochemistry — Posted on 2019-03-18 1474 Consequences Of NMDA Receptor Deficiency Can Be Rescued In The Adult Brain Mielnik, C. A.; Binko, M. A.; Islam, R.; Johansson, E. M.; Funk, A. J.; Chen, Y.; Milenkovic, M.; Horsfall, W.; Ross, R. A.; Groc, L.; Salahpour, A.; McCullumsmith, R. E.; Lambe, E. K.; Ramsey, A. J. 10.1101/140343 — neuroscience — Posted on 2019-03-18 1475 Host-pathogen transcriptomics of macrophages, Mucorales and their endosymbionts: a polymicrobial pas de trois Sephton-Clark, P.; Itabangi, H.; Munoz, J. F.; Voelz, K.; Cuomo, C.; Ballou, E. 10.1101/580746 — microbiology — Posted on 2019-03-18 1476 Pan-GWAS of Streptococcus agalactiae highlights lineage specific genes associated with virulence and niche adaptation Gori, A.; Harrison, O.; Mlia, E.; Nishihara, Y.; Chinkwita-Phiri, J.; Mallewa, M.; Dube, Q.; Swarthout, T. D.; Nobbs, A. H.; Maiden, M.; French, N.; Heyderman, R. S. 10.1101/574152 — genomics — Posted on 2019-03-18 1477 CellTag Indexing: genetic barcode-based sample multiplexing for single-cell genomics Guo, C.; Kong, W.; Kamimoto, K.; Rivera Gonzalez, G. C. C.; Yang, X.; Kirita, Y.; Morris, S. A. 10.1101/335547 — genomics — Posted on 2019-03-18 1478 Insight into the genetic aetiology of retinal detachment by combining small clinical and large population-based datasets Boutin, T. S.; Charteris, D. G.; Chandra, A.; Campbell, S.; Hayward, C.; Campbell, A.; UK Biobank Eye & Vision Consortium, ; Nandakumar, P.; Hinds, D.; 23andMe Research Team, ; Mitry, D.; Vitart, V. 10.1101/581165 — genetics — Posted on 2019-03-18 1479 Estimating narrow-sense heritability from genome-wide data in admixed populations Athanasiadis, G.; Speed, D.; Andersen, M. K.; Appel, E. V. R.; Grarup, N.; Brandslund, I.; Joergensen, M. E.; Larsen, C. V. L.; Bjerregaard, P.; Hansen, T.; Albrechtsen, A. 10.1101/581389 — genetics — Posted on 2019-03-18 1480 Labour sharing promotes coexistence in atrazine degrading bacterial communities Billet, L.; Devers, M.; Rouard, N.; Martin-Laurent, F.; Spor, A. 10.1101/581041 — evolutionary biology — Posted on 2019-03-18 1481 Long-term reduction of short wavelength light affects sustained attention and visuospatial working memory. Domagalik, A.; Oginska, H.; Beldzik, E.; Fafrowicz, M.; Marek, T. 10.1101/581314 — animal behavior and cognition — Posted on 2019-03-18 1482 PERK inhibition mitigates restenosis and thrombosis - a potential low-thrombogenic anti-restenotic paradigm Wang, B.; Zhang, M.; Urabe, G.; Chen, G.; Wheeler, D.; Dornbos, D.; Huttinger, A.; Huang, Y.; Nimjee, S.; Gong, S.; Guo, L.; Kent, K. C. 10.1101/581397 — pathology — Posted on 2019-03-18 1483 Tissue mechanics controls T-cell activation and metabolism Meng, K.; Majedi, F. S.; Thauland, T. J.; Butte, M. 10.1101/581322 — immunology — Posted on 2019-03-18 1484 Schizophrenia Polygenic Risk Score and 20-Year Course of Illness in Psychotic Disorders Jonas, K. G.; Lencz, T.; Li, K.; Malhotra, A. K.; Perlman, G.; Fochtmann, L. J.; Bromet, E.; Kotov, R. 10.1101/581579 — genetics — Posted on 2019-03-18 1485 De novo Identification of Essential Protein Domains from CRISPR/Cas9 Tiling-sgRNA Knockout Screens He, W.; Zhang, L.; Villarreal, O. D.; Fu, R.; Bedford, E.; Dou, J.; Bedford, M. T.; Shi, X.; Chen, T.; Bartholomew, B.; Xu, H. 10.1101/581751 — bioinformatics — Posted on 2019-03-18 1486 Sex differences in reward- and punishment-guided actions Tara, C. G.; Wallin-Miller, K. G.; Rear, A. A.; Park, J.; Diaz, V.; Simon, N. W.; Moghaddam, B. 10.1101/581546 — animal behavior and cognition — Posted on 2019-03-18 1487 A simple model of a quadruped discovers single-foot walking and trotting as energy optimal strategies Polet, D. T.; Bertram, J. E. A. 10.1101/580779 — zoology — Posted on 2019-03-18 1488 The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue Voigt, F.; Kirschenbaum, D.; Platonova, E.; Pages, S.; Campbell, R. A. A.; Kaestli, R.; Schaettin, M.; Egolf, L.; van der Bourg, A.; Bethge, P.; Haenraets, K.; Frezel, N.; Topilko, T.; Perin, P.; Hillier, D.; Hildebrand, S.; Schueth, A.; Roebroeck, A.; Roska, B.; Stoeckli, E.; Pizzala, R.; Renier, N.; Zeilhofer, H. U.; Karayannis, T.; Ziegler, U.; Batti, L.; Holtmaat, A.; Lüscher, C.; Aguzzi, A.; Helmchen, F. 10.1101/577122 — neuroscience — Posted on 2019-03-18 1489 Integrating electric field modelling and neuroimaging to explain variability of low intensity tES effects Kasten, F. H.; Duecker, K.; Meiser, A.; Herrmann, C. S. 10.1101/581207 — neuroscience — Posted on 2019-03-18 1490 Predicting the effects of SNPs on transcription factor binding affinity Nishizaki, S. S.; Ng, N.; Dong, S.; Morterud, C.; Williams, C.; Boyle, A. P. 10.1101/581306 — bioinformatics — Posted on 2019-03-18 1491 Crystal structure of the LRR ectodomain of the plant immune receptor kinase SOBIR1. Hohmann, U.; Hothorn, M. 10.1101/581231 — plant biology — Posted on 2019-03-18 1492 Molecular mechanisms for intestinal HCO3- secretion and its regulation by guanylin in seawater-acclimated eels Takei, Y.; Wong, M. K. S.; Ando, M. 10.1101/580761 — physiology — Posted on 2019-03-18 1493 Specific oligodendrocyte populations have differential spatial distribution and susceptibility to injury Floriddia, E. M.; Zhang, S.; van Bruggen, D.; Goncalves dos Santos, J. P.; Altinkok, M.; Foerster, S.; Tripathi, R. B.; Richardson, W. D.; Franklin, R. J. M.; Castelo-Branco, G. 10.1101/580985 — neuroscience — Posted on 2019-03-18 1494 Increased hippocampal excitability and reduced modulation in relevant neural networks underlying age-related cognitive mapping deficits Diersch, N.; Valdes-Herrera, J. P.; Tempelmann, C.; Wolbers, T. 10.1101/581108 — neuroscience — Posted on 2019-03-18 1495 Predictive Coding beyond simple tone-based oddball designs Vidal, Y.; Brusini, P.; Bonfieni, M.; Mehler, J.; Bekinschtein, T. 10.1101/581355 — neuroscience — Posted on 2019-03-18 1496 Schwann cell demyelination is triggered by a transient mitochondrial calcium release through Voltage Dependent Anion Channel 1 Tricaud, N.; Gautier, B.; Van Hameren, G.; Berthelot, J.; Gonzalez, S.; Chrast, R. 10.1101/581157 — neuroscience — Posted on 2019-03-18 1497 Growth Mode and Carbon Source Impact the Surfaceome Dynamics of Lactobacillus rhamnosus GG Savijoki, K.; Nyman, T. A.; Kainulainen, V.; Miettinen, I.; Siljamäki, P.; Fallarero, A.; Sandholm, J.; Satokari, R.; Varmanen, P. 10.1101/579953 — microbiology — Posted on 2019-03-18 1498 Development of a deep amplicon sequencing method to determine the proportional species composition of piroplasm haemoprotozoa as an aid in their control Chaudhry, U.; Ali, Q.; Rashid, I.; Shabbir, M. Z.; Abbas, M.; Numan, M.; Evans, M.; Ashraf, K.; Morrison, I.; Morrison, L.; Sargison, N. D. 10.1101/580183 — microbiology — Posted on 2019-03-18 1499 Genomic dissection of maternal, additive and non-additive genetic effects for growth and carcass traits in Nile tilapia Joshi, R.; Woolliams, J.; Meuwissen, T.; Gjoen, H. M. 10.1101/579334 — genomics — Posted on 2019-03-18 1500 The distinct phenotypic signatures of dispersal and stress in an arthropod model: from physiology to life history Dahirel, M.; Masier, S.; Renault, D.; Bonte, D. 10.1101/581116 — ecology — Posted on 2019-03-18 1501 A game theoretic approach to deciphering the dynamics of amyloid-β aggregation along competing pathways Ghosh, P.; Rana, P.; Rangachari, V.; Saha, J.; Steen, E.; Vaidya, A. 10.1101/581629 — biophysics — Posted on 2019-03-18 1502 Aromatic polyketide biosynthesis: fidelity, evolution and engineering Qin, Z.; Devine, R.; Hutchings, M. I.; Wilkinson, B. 10.1101/581074 — bioengineering — Posted on 2019-03-18 1503 KHNYN is essential for ZAP-mediated restriction of HIV-1 containing clustered CpG dinucleotides Ficarelli, M.; Wilson, H.; Pedro Galao, R.; Neil, S.; Swanson, C. M. 10.1101/581785 — immunology — Posted on 2019-03-18 1504 PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions Grebenova, D.; Holoubek, A.; Röselova, P.; Obr, A.; Brodska, B.; Kuzelova, K. 10.1101/580928 — cell biology — Posted on 2019-03-18 1505 Ultrasound Imaging of Gene Expression in Mammalian Cells Farhadi, A.; Ho, G. H.; Sawyer, D. P.; Bourdeau, R. W.; Shapiro, M. G. 10.1101/580647 — bioengineering — Posted on 2019-03-18 1506 Exceptional subgenome stability and functional divergence in allotetraploid teff, the primary cereal crop in Ethiopia VanBuren, R.; Wai, C. M.; Pardo, J.; Yocca, A. E.; Wang, X.; Wang, H.; Chaluvadi, S. R.; Bryant, D.; Edger, P. P.; Bennetzen, J. L.; Mockler, T. C.; Michael, T. P. 10.1101/580720 — plant biology — Posted on 2019-03-18 1507 Overt and covert paths for sound in the auditory system of mammals Auriol, B. M.; Auriol, B.; Beard, J.; Bibe, B.; Broto, J.-M.; Descouens, D.; Durand, L. J.; Florens, J.-P.; Garcia, F.; Joiner, E.; Libes, B.; Pergent, P.; Ruiz, R.; Thalamas, C. 10.1101/561779 — physiology — Posted on 2019-03-18 1508 The Fruit Fly Brain Observatory: From Structure to Function Ukani, N. H.; Yeh, C.-H.; Tomkins, A.; Zhou, Y.; Florescu, D.; Luna Ortiz, C.; Huang, Y.-C.; Wang, C.-T.; Turkcan, M. K.; Liu, T.; Richmond, P.; Lo, C.-C.; Coca, D.; Chiang, A.-S.; Lazar, A. A. 10.1101/580290 — neuroscience — Posted on 2019-03-18 1509 Atypical developmental features of cortical thickness trajectories in Autism Spectrum Disorder Nunes, A. S.; Vakorin, V. A.; Kozhemiako, N.; Peatfield, N.; Ribary, U.; Doesburg, S. 10.1101/580837 — neuroscience — Posted on 2019-03-18 1510 Dissociable neural circuits underlie the resolution of three discrete sources of competition during task-switching. Burke, K. M.; Molholm, S.; Butler, J. S.; Ross, L. A.; Foxe, J. J. 10.1101/581777 — neuroscience — Posted on 2019-03-18 1511 A comprehensive map of the dendritic cell transcriptional network engaged upon innate sensing of HIV Johnson, J. S.; De Veaux, N.; Rives, A. W.; Lahaye, X.; Lucas, S. Y.; Perot, B.; Luka, M.; Amon, L. M.; Watters, A.; Aderem, A.; Manel, N.; Littman, D. R.; Bonneau, R.; Menager, M. M. 10.1101/579920 — immunology — Posted on 2019-03-18 1512 Selection and gene flow shape niche-associated copy-number variation of pheromone receptor genes Lee, D.; Zdraljevic, S.; Cook, D. E.; Frezal, L.; Hsu, J.-C.; Sterken, M. G.; Riksen, J. A. G.; Wang, J.; Kammenga, J. E.; Braendle, C.; Felix, M.-A.; Schroeder, F. C.; Andersen, E. C. 10.1101/580803 — evolutionary biology — Posted on 2019-03-18 1513 Ring canals permit extensive cytoplasm sharing among germline cells independent of fusomes in Drosophila testes Kaufman, R. S.; Price, K. L.; Mannix, K.; Ayers, K.; Hudson, A. M.; Cooley, L. 10.1101/581702 — developmental biology — Posted on 2019-03-18 1514 An efficient timer and sizer of biomacromolecular motions Chan, J.; Lin, H.-R.; Takemura, K.; Chang, K.-C.; Chang, Y.-Y.; Joti, Y.; Kitao, A.; Yang, L.-W. 10.1101/384511 — biophysics — Posted on 2019-03-18 1515 The structural evolution of host-pathogen protein interactions: an integrative approach Brito, A. F.; Pinney, J. W. 10.1101/581637 — bioinformatics — Posted on 2019-03-18 1516 Data Distribution for Phylogenetic Inference with Site Repeats via Judicious Hypergraph Partitioning Baar, I.; Hubner, L.; Oettig, P.; Zapletal, A.; Schlag, S.; Stamatakis, A.; Morel, B. 10.1101/579318 — bioinformatics — Posted on 2019-03-18 1517 Transient upregulation of translational efficiency in prodromal Tg2576 mice precipitates AD symptoms Borreca, A.; Valeri, F.; De Luca, M.; Ernst, L.; Russo, A.; Cordella, A.; Corsetti, V.; Nobili, A.; Amadoro, G.; Mercuri, N. B.; D'Amelio, M.; Ammassari-Teule, M. 10.1101/581652 — neuroscience — Posted on 2019-03-18 1518 Genomic analysis unveils important aspects of population structure, virulence, and antimicrobial resistance in Klebsiella aerogenes Passarelli-Araujo, H.; Palmeiro, J. K.; Moharana, K. C.; Pedrosa-Silva, F.; Dalla-Costa, L.; Venancio, T. M. 10.1101/581645 — genomics — Posted on 2019-03-18 1519 PP2A inhibitor PME-1 suppresses anoikis, and is associated with therapy relapse of PTEN-deficient prostate cancers Rupp, C.; Aakula, A.; Isomursu, A.; Erickson, A.; Kauko, O.; Shah, P.; Padzik, A.; Kaur, A.; Li, S.-P.; Pokharel, Y. R.; Trottman, L.; Rannikko, A.; Taimen, P.; Lammerding, J.; Paatero, I.; Mirtti, T.; Ivaska, J.; Westermarck, J. 10.1101/581660 — cancer biology — Posted on 2019-03-18 1520 Sign-tracking behavior is difficult to extinguish and resistant to multiple cognitive enhancers Fitzpatrick, C. J.; Geary, T.; Creeden, J. F.; Morrow, J. D. 10.1101/581769 — animal behavior and cognition — Posted on 2019-03-18 1521 Hi-C guided assemblies reveal conserved regulatory topologies on X and autosomes despite extensive genome shuffling Renschler, G.; Richard, G.; Keller Valsecchi, C.; Toscano, S.; Arrigoni, L.; Ramirez, F.; Akhtar, A. 10.1101/580969 — genomics — Posted on 2019-03-18 1522 CGAT-core: a python framework for building scalable, reproducible computational biology workflows Cribbs, A.; Luna-Valero, S.; George, C.; Sudbery, I. M.; Berlanga-Taylor, A. J.; Sansom, S. N.; Smith, T.; Ilott, N. E.; Johnson, J.; Scaber, J.; Brown, K.; Sims, D.; Heger, A. 10.1101/581009 — genomics — Posted on 2019-03-18 1523 T-cell activation is modulated by the 3D mechanical microenvironment Majedi, F. S.; Hasani-Sadrabadi, M. M.; Thauland, T. J.; Song, L.; Bouchard, L.-S.; Butte, M. J. 10.1101/580886 — immunology — Posted on 2019-03-18 1524 Protein fold prediction using simulated DEER distance distributions and decay traces del Alamo, D.; Tessmer, M.; Stein, R. A.; Feix, J. B.; Mchaourab, H. S.; Meiler, J. 10.1101/581181 — biophysics — Posted on 2019-03-18 1525 ROS accumulation and associated cell death mediates susceptibility to Alternaria brassicae in Arabidopsis accessions Mandal, S.; Rajarammohan, S.; Kaur, J. 10.1101/581025 — plant biology — Posted on 2019-03-18 1526 Multi-omics integration of the phenome, transcriptome and genome highlights genes and pathways relevant to essential tremor Liao, C.; Sarayloo, F.; Rochefort, D.; Houle, G.; Akcimen, F.; He, Q.; Laporte, A. D.; Spiegelman, D.; Rajput, A.; Dion, P. A.; Rouleau, G. A. 10.1101/580753 — genomics — Posted on 2019-03-18 1527 Substrate-rigidity dependent migration of an idealized twitching bacterium Simsek, A. N.; Braeutigam, A.; Koch, M.; Shaevitz, J.; Huang, Y.; Gompper, G.; Sabass, B. 10.1101/581348 — biophysics — Posted on 2019-03-18 1528 Ultra-compliant carbon nanotube stretchable direct bladder interface Yan, D.; Bruns, T. M.; Wu, Y.; Zimmerman, L. L.; Stephan, C.; Cameron, A. P.; Yoon, E.; Seymour, J. P. 10.1101/580902 — bioengineering — Posted on 2019-03-18 1529 The lncRNA NEAT1_1 is dispensable for normal tissue homeostasis and cancer cell growth Adriaens, C.; Rambow, F.; Bervoets, G.; Silla, T.; Mito, M.; Chiba, T.; Hiroshi, A.; Hirose, T.; Nakagawa, S.; Jensen, T. H.; Marine, J.-C. 10.1101/574582 — molecular biology — Posted on 2019-03-18 1530 ELIMINATION OF EGFR-OVEREXPRESSING CANCER CELLS BY CD32 CHIMERIC RECEPTOR T CELLS IN COMBINATION WITH CETUXIMAB OR PANITUMUMAB Caratelli, S.; Arriga, R.; Sconocchia, T.; Ottaviani, A.; Lanzilli, G.; Pastore, D.; Cenciarelli, C.; Venditti, A.; Del Principe, M. I.; Lauro, D.; Landoni, E.; Du, H.; Savoldo, B.; Ferrone, S.; Dotti, G.; Sconocchia, G. 10.1101/581017 — immunology — Posted on 2019-03-18 1531 Studying ecosystems with DNA metabarcoding: lessons from aquatic biomonitoring Bush, A.; Compson, Z.; Monk, W.; Porter, T.; Steeves, R.; Emilson, E.; Gagne, N.; Hajibabaei, M.; Roy, M.; Baird, D. 10.1101/578591 — ecology — Posted on 2019-03-18 1532 How sequence alignment scores correspond to probability models Frith, M. 10.1101/580951 — bioinformatics — Posted on 2019-03-18 1533 A Methylation Density Binary Classifier for Predicting and Optimizing the Performance of Methylation Biomarkers in Clinical Samples Miller, B. F.; Pisanic, T. R.; Margolin, G.; Petrykowska, H. M.; Athamanolap, P.; Osei-Tutu, A.; Annunziata, C. M.; Wang, T.-H.; Elnitski, L. 10.1101/579839 — bioinformatics — Posted on 2019-03-18 1534 Coloring Single Nanoparticle Trajectory on Live Cell Membrane with its Own History: a Presuppositionless Approach Zhao, H.; Huang, Z.; Ge, F.; Shi, X.; Bin, X.; Liao, X.; Wang, Z.; Zhang, S.; Zhang, X.; He, Y. 10.1101/580480 — biophysics — Posted on 2019-03-18 1535 ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics Caldas, P.; Lopez-Pelegrin, M.; Pearce, D. J. G.; Budanur, N. B.; Brugues, J.; Loose, M. 10.1101/580944 — biophysics — Posted on 2019-03-18 1536 Luciferase-LOV BRET enables versatile and specific transcriptional readout of cellular protein-protein interactions Kim, C. K.; Cho, K. F.; Kim, M. W.; Ting, A. Y. 10.1101/580845 — bioengineering — Posted on 2019-03-18 1537 Asymmetric sampling in human auditory cortex reveals spectral processing hierarchy Giroud, J.; Trebuchon, A.; Schön, D.; Marquis, P.; Liegeois-Chauvel, C.; Poeppel, D.; Morillon, B. 10.1101/581520 — neuroscience — Posted on 2019-03-18 1538 The parietal operculum preferentially encodes heat pain and not salience Horing, B.; Sprenger, C.; Büchel, C. 10.1101/581504 — neuroscience — Posted on 2019-03-18 1539 Genetic interactions affect lung function in patients with systemic sclerosis Tyler, A. L.; Mahoney, J. M.; Carter, G. W. 10.1101/581553 — genetics — Posted on 2019-03-18 1540 Emerging arbovirosis (Dengue, Chikungunya, Zika) in the Southeastern Mexico: influence of social and environmental determinants on knowledge and practices. A mixed method study Causa, R.; Luque-Fernandez, M. A.; Ochoa, H.; Dor, A.; Rodriguez, F.; Solis, R.; Pacheco, A. L. 10.1101/581603 — epidemiology — Posted on 2019-03-18 1541 Homeostasis of the intervertebral disc requires regulation of STAT3 signaling by the adhesion G-protein coupled receptor ADGRG6 Liu, Z.; Easson, G.; Zhao, J.; Makki, N.; Ahituv, N.; Hilton, M.; Tang, S.; Gray, R. S. 10.1101/581595 — developmental biology — Posted on 2019-03-18 1542 Analysis of physiological noise in quantitative cardiac magnetic resonance Jao, T.; Nayak, K. 10.1101/581496 — bioengineering — Posted on 2019-03-18 1543 Naturally Produced Lovastatin Modifies the Histology and Proteome Profile of Goat Skeletal Muscle Leo, T. K.; Garba, S.; Danmaigoro, A.; Sazili, A. Q.; Candyrine, S. C. L.; Jahromi, M. F.; Goh, Y. M.; Ronimus, R.; Muetzel, S.; Liang, J. B. 10.1101/581439 — molecular biology — Posted on 2019-03-18 1544 Very severe anemia and one year mortality outcome after hospitalization in Tanzanian children: A prospective cohort study Chami, N.; Hau, D. K.; Masoza, T. S.; Smart, L. R.; Kayange, N. M.; Hokororo, A.; Ambrose, E. E.; Moschovis, P. P.; Wiens, M. O.; Peck, R. N. 10.1101/581462 — epidemiology — Posted on 2019-03-18 1545 Automated segmentation of cortical layers in BigBrain reveals divergent cortical and laminar thickness gradients in sensory and motor cortices. Wagstyl, K.; Larocque, S.; Cucurull, G.; Lepage, C.; Cohen, J. P.; Bludau, S.; Palomero-Gallagher, N.; Funck, T.; Spitzer, H.; Dicksheid, T.; Fletcher, P. C.; Romero, A.; Zilles, K.; Amunts, K.; Bengio, Y.; Evans, A. C. 10.1101/580597 — neuroscience — Posted on 2019-03-17 1546 Visualization of Loki- and Heimdallarchaeia (Asgardarchaeota) by fluorescence in situ hybridization and catalyzed reporter deposition (CARD-FISH) Salcher, M.; Andrei, A.-S.; Bulzu, P.-A.; Keresztes, Z. G.; Banciu, H. L.; Ghai, R. 10.1101/580431 — microbiology — Posted on 2019-03-17 1547 HIV reservoir size is determined prior to ART initiation and linked to CD8 T cell activation and memory expansion Martin, G. E.; Pace, M.; Shearer, F.; Zilber, E.; Hurst, J.; Meyerowitz, J.; Thornhill, J. P.; Lwanga, J.; Brown, H.; Robinson, N.; Hopkins, E.; Olejniczak, N.; Nwokolo, N.; Fox, J.; Fidler, S.; Willberg, C.; Frater, J.; CHERUB investigators, 10.1101/580308 — immunology — Posted on 2019-03-17 1548 Variation in phosphorus and sulfur content shapes the genetic architecture and phenotypic associations within wheat grain ionome Fatiukha, A.; Klymiuk, V.; Peleg, Z.; Saranga, Y.; Cakmak, I.; Krugman, T.; Korol, A. B.; Fahima, T. 10.1101/580423 — genetics — Posted on 2019-03-17 1549 Static and Dynamic Functional Connectivity Analysis of Cerebrovascular Reactivity: An fMRI Study Lewis, N.; Lu, H.; Liu, P.; Hou, X.; Damaraju, E.; Iraji, A.; Calhoun, V. 10.1101/580621 — neuroscience — Posted on 2019-03-17 1550 Enhancing DNA metabarcoding performance and applicability with bait capture enrichment and DNA from conservative ethanol Gauthier, M.; Konecny, L.; Nguyen, A.; Elbrecht, V.; Datry, T.; Douady, C.; Lefebure, T. 10.1101/580464 — molecular biology — Posted on 2019-03-17 1551 A Sex-Specific Switch in Platelet Receptor Signaling Following Myocardial Infarction Cameron, S. J.; Kim, B. S.; Auerbacj, D.; Sadhra, H.; Ling, F. S.; Toth, S.; Mohan, A.; Ture, S.; Goldenberg, I.; Rich, D. 10.1101/580415 — molecular biology — Posted on 2019-03-17 1552 The structure of Macrophage Expressed Gene-1, a phagolysosome immune effector that is activated upon acidification. Pang, S. S.; Bayly-Jones, C.; Radjainia, M.; Spicer, B. A.; Law, R. H. P.; Hodel, A. W.; Ekkel, S. M.; Conroy, P. J.; Ramm, G.; Venugopal, H.; Bird, P. I.; Hoogenboom, B. W.; Voskoboinik, I.; Gambin, Y.; Sierecki, E.; Dunstone, M. A.; Whisstock, J. C. 10.1101/580712 — biochemistry — Posted on 2019-03-17 1553 Regulation of hippocampal memory by mTORC1 in somatostatin interneuron Artinian, J.; Jordan, A.; Khlaifia, A.; Honore, E.; La Fontaine, A.; Racine, A.-S.; Laplante, I.; Lacaille, J.-C. 10.1101/580670 — neuroscience — Posted on 2019-03-17 1554 An investigation into serotonergic and environmental interventions against depression in a simulated delayed reward paradigm Porr, B.; Trew, A.; Miller, A. 10.1101/580456 — neuroscience — Posted on 2019-03-17 1555 Synthesizing Disparate LiDAR and Satellite Datasets through Deep Learning to Generate Wall-to-Wall Forest Inventories of New England Ayrey, E.; Hayes, D. J.; Kilbride, J. B.; Weiskittel, A. R. 10.1101/580514 — ecology — Posted on 2019-03-17 1556 Metabolic activity affects response of single cells to a nutrient switch in structured populations Dal Co, A.; Ackermann, M.; van Vliet, S. 10.1101/580563 — systems biology — Posted on 2019-03-17 1557 Vaccine blunts fentanyl potency in male rhesus monkeys Tenney, R. D.; Blake, S.; Bremer, P. T.; Zhou, B.; Hwang, C. S.; Poklis, J. L.; Janda, K. D.; Banks, M. 10.1101/580100 — neuroscience — Posted on 2019-03-17 1558 Task errors drive memories that improve sensorimotor adaptation. Leow, L.-A.; Marinovic, W.; de Rugy, A.; Carroll, T. J. 10.1101/538348 — neuroscience — Posted on 2019-03-17 1559 Generation of scale-invariant sequential activity in linear recurrent networks Liu, Y.; Howard, M. W. 10.1101/580522 — neuroscience — Posted on 2019-03-17 1560 The intestinal microbiota programs diurnal rhythms in host metabolism through histone deacetylase 3 Kuang, Z.; Wang, Y.; Li, Y.; Ye, C.; Ruhn, K. A.; Behrendt, C. L.; Olson, E. N.; Hooper, L. V. 10.1101/580613 — microbiology — Posted on 2019-03-17 1561 Shared polygenetic variation between ASD and ADHD exerts opposite association patterns with educational attainment Verhoef, E.; Grove, J.; Shapland, C. Y.; Demontis, D.; Burgess, S.; Rai, D.; Borglum, A. D.; St Pourcain, B. 10.1101/580365 — genetics — Posted on 2019-03-17 1562 Evaluation of gene expression and phenotypic profiling data as quantitative descriptors for predicting drug targets and mechanisms of action Lapins, M.; Spjuth, O. 10.1101/580654 — bioinformatics — Posted on 2019-03-17 1563 Rational use of Episodic and Working Memory: A Normative Account of Prospective Memory Momennejad, I.; Norman, K. A.; Cohen, J. D.; Singh, S.; Lewis, R. L. 10.1101/580324 — animal behavior and cognition — Posted on 2019-03-17 1564 High-intensity interval training blunts exercise-induced changes in markers of mitochondrial biogenesis in human skeletal muscle Granata, C.; Oliveira, R. S. F.; Little, J. P.; Bishop, D. J. 10.1101/580373 — physiology — Posted on 2019-03-17 1565 Bottleneck revisited: increased adaptive variation despite reduced overall genetic diversity in a rapidly adapting invader Selechnik, D.; Richardson, M. F.; Shine, R.; DeVore, J.; Ducatez, S.; Rollins, L. A. 10.1101/557868 — evolutionary biology — Posted on 2019-03-17 1566 Restored alveolar epithelial differentiation and reversed human lung fibrosis upon Notch inhibition Wasnick, R. M.; Korfei, M.; Piskulak, K.; Henneke, I.; Wilhelm, J.; Mahavadi, P.; von der Beck, D.; Koch, M.; Shalashova, I.; Klymenko, O.; Fink, L.; Witt, H.; Hackstein, H.; El Agha, E.; Bellusci, S.; Klepetko, W.; Koenigshoff, M.; Eickelberg, O.; Braun, T.; Seeger, W.; Ruppert, C.; Guenther, A. 10.1101/580498 — cell biology — Posted on 2019-03-17 1567 PlotsOfDifferences - a web app for the quantitative comparison of unpaired data Goedhart, J. 10.1101/578575 — scientific communication and education — Posted on 2019-03-17 1568 Loss of Bardet-Biedl syndrome proteins causes synaptic aberrations in principal neurons Haq, N.; Schmidt-Hieber, C. S.-H.; Sialana, F. J.; Ciani, L.; Heller, J. P.; Stewart, M.; Bentley, L.; Wells, S.; Rodenburg, R. J.; Nolan, P. M.; Forsythe, E.; Wu, M. C.; Lubec, G.; Hausser, M.; Beales, P.; Christou-Savina, S. 10.1101/580399 — cell biology — Posted on 2019-03-17 1569 A deep learning framework for nucleus segmentation using image style transfer Hollandi, R.; Szkalisity, A.; Toth, T.; Tasnadi, E.; Molnar, C.; Mathe, B.; Grexa, I.; Molnar, J.; Balind, A.; Gorbe, M.; Kovacs, M.; Migh, E.; Goodman, A.; Balassa, T.; Koos, K.; Wang, W.; Bara, N.; Kovacs, F.; Paavolainen, L.; Danka, T.; Kriston, A.; Carpenter, A. E.; Smith, K.; Horvath, P. 10.1101/580605 — bioinformatics — Posted on 2019-03-17 1570 Structural basis for the delivery of activated sialic acid into Golgi for sialyation Nji, E.; Gulati, A.; Qureshi, A. A.; Coincon, M.; Drew, D. 10.1101/580449 — biochemistry — Posted on 2019-03-17 1571 Differential and Age Dependent Expression of Specific Sialoglycans on HeLa Cells -Revealed by Direct Fluorescent Glycan Labeling Wu, Z.; Person, A. D.; Burton, A. J.; Singh, R.; Burroughs, B.; Fryxell, D.; Tatge, T. J.; Manning, T.; Wu, G.; Swift, K.; Kalabokis, V. 10.1101/580571 — cancer biology — Posted on 2019-03-17 1572 A haplotype-aware de novo assembly of related individuals using pedigree graph Garg, S.; Aach, J.; Li, H.; Durbin, R.; Church, G. 10.1101/580159 — bioinformatics — Posted on 2019-03-17 1573 ProtCID: A tool for hypothesis generation of the structures of protein interactions Xu, Q.; Dunbrack, R. L. 10.1101/579862 — bioinformatics — Posted on 2019-03-17 1574 Entrainment of local synchrony reveals a causal role for high-beta right frontal oscillations in human visual consciousness Vernet, M.; Stengel, C.; Quentin, R.; Amengual, J. L.; Valero-Cabre, A. 10.1101/574939 — neuroscience — Posted on 2019-03-17 1575 Determinants of QTL mapping power in the realized Collaborative Cross Keele, G. R.; Crouse, W. L.; Kelada, S. N. P.; Valdar, W. 10.1101/459966 — genetics — Posted on 2019-03-17 1576 The importance of neutral over niche processes in structuring Ediacaran early animal communities Mitchell, E. G.; Harris, S.; Kenchington, C.; Vixseboxse, P.; Roberts, L.; Dennis, A.; Clark, C.; Liu, A.; Wilby, P. 10.1101/443275 — ecology — Posted on 2019-03-17 1577 5-methoxy-N,N-dimethyltryptamine: An ego-dissolving endogenous neurochemical catalyst of creativity Germann, C. B. 10.1101/578435 — neuroscience — Posted on 2019-03-17 1578 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive Choudhary, S. 10.1101/578500 — bioinformatics — Posted on 2019-03-17 1579 Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation Kelmer Sacramento, E.; Kirkpatrick, J. M.; Mazzetto, M.; Di Sanzo, S.; Caterino, C.; Sanguanini, M.; Papaevgeniou, N.; Lefaki, M.; Childs, D.; Bagnoli, S.; Terzibasi Tozzini, E.; Bartolome, A.; Romanov, N.; Baumgart, M.; Huber, W.; Chondrogianni, N.; Vendruscolo, M.; Cellerino, A.; Ori, A. 10.1101/577478 — systems biology — Posted on 2019-03-17 1580 When can we trust population trends? A method for quantifying the effects of sampling interval and duration Wauchope, H. S.; Amano, T.; Sutherland, W. J.; Johnston, A. 10.1101/498170 — ecology — Posted on 2019-03-17 1581 Mapping drinking water and quality of life aspects in urban settings: an application of the urban exposome Andrianou, X. D.; van der Lek, C.; Charisiadis, P.; Ioannou, S.; Fotopoulou, K. N.; Papapanagiotou, Z.; Botsaris, G.; Beumer, C.; Makris, K. C. 10.1101/401927 — epidemiology — Posted on 2019-03-17 1582 A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial-Mesenchymal Transition in Breast Cancer Cells Dang, D. K.; Makena, M. R.; Llongueras, J. P.; Prasad, H.; Ko, M.; Bandral, M.; Rao, R. 10.1101/379586 — cancer biology — Posted on 2019-03-17 1583 Morphine analgesia and mu opioid receptor signaling require programed death protein 1 (PD-1) Wang, Z.; Jiang, C.; He, Q.; Matsuda, M.; Han, Q.; Wang, K.; Bang, S.; Ji, R.-R. 10.1101/580506 — neuroscience — Posted on 2019-03-17 1584 An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling Pagliuso, A.; Tham, T. N.; Allemand, E.; Robertin, S.; Dupuy, B.; Bertrand, Q.; Becavin, C.; Koutero, M.; Najburg, V.; Nahori, M.-A.; Stavru, F.; Dessen, A.; Muchard, C.; Lebreton, A.; Komarova, A. V.; Cossart, P. 10.1101/543652 — cell biology — Posted on 2019-03-17 1585 Zebrafish larvae as a model system for systematic characterization of drugs and genes in dyslipidemia and atherosclerosis Bandaru, M. K. K.; Emmanouilidou, A.; Ranefall, P.; von der Heyde, B.; Mazzaferro, E.; Klingstroem, T.; Masiero, M.; Dethlefsen, O.; Ledin, J.; Larsson, A.; Brooke, H. L.; Wahlby, C.; Ingelsson, E.; den Hoed, M. 10.1101/502674 — genomics — Posted on 2019-03-17 1586 Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies Park, S.; Park, S.-K.; Watanabe, N.; Hashimoto, T.; Iwatsubo, T.; Shelkovnikova, T. A.; Liebman, S. W. 10.1101/415927 — molecular biology — Posted on 2019-03-17 1587 Mendelian Randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits Porcu, E.; Rüeger, S.; Lepik, K.; eQTLGen Consortium, ; Santoni, F. A.; Reymond, A.; Kutalik, Z. 10.1101/377267 — genetics — Posted on 2019-03-17 1588 The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology Chen, J. L.; Moss, W. N.; Spencer, A.; Zhang, P.; Childs-Disney, J. L.; Disney, M. D. 10.1101/580407 — bioinformatics — Posted on 2019-03-17 1589 The role of mutation bias in adaptive molecular evolution: insights from convergent changes in protein function Storz, J. F.; Natarajan, C.; Signore, A. V.; Witt, C. C.; McCandlish, D. M.; Stoltzfus, A. 10.1101/580175 — evolutionary biology — Posted on 2019-03-17 1590 Improving imputation quality in BEAGLE for crop and livestock data Pook, T.; Mayer, M.; Geibel, J.; Weigend, S.; Cavero, D.; Schön, C.-C.; Simianer, H. 10.1101/577338 — genetics — Posted on 2019-03-16 1591 Toxic Benthic Filamentous Cyanobacteria in Lakes and Rivers of South-Central Quebec, Canada Husk, B.; Nieuwenhuis, D. 10.1101/580035 — plant biology — Posted on 2019-03-16 1592 Pupillometry as an objective measure of sustained attention in young and older listeners Zhao, S.; Bury, G.; Milne, A.; Chait, M. 10.1101/579540 — neuroscience — Posted on 2019-03-16 1593 Large-scale functional connectivity in multisensory cortex predicts performance Hollensteiner, K. J.; Galindo-Leon, E.; Pieper, F.; Engler, G.; Nolte, G.; Engel, A. K. 10.1101/579938 — neuroscience — Posted on 2019-03-16 1594 A candidate causal variant underlying both higher intelligence and increased risk of bipolar disorder Shen, S. Q.; Kim-Han, J. S.; Cheng, L.; Xu, D.; Gokcumen, O.; Hughes, A. E.; Myers, C. A.; Corbo, J. C. 10.1101/580258 — genetics — Posted on 2019-03-16 1595 fuNTRp: Identifying protein positions for variation driven functional tuning Miller, M.; Vitale, D.; Rost, B.; Bromberg, Y. 10.1101/578757 — bioinformatics — Posted on 2019-03-16 1596 Virtual reality for animal navigation with camera-based optical flow tracking Vishniakou, I.; Ploeger, P. G.; Seelig, J. 10.1101/579813 — neuroscience — Posted on 2019-03-16 1597 Nitroxide functionalized antibiotics are promising eradication agents against Staphylococcus aureus biofilms. Verderosa, A. D.; Dhouib, R.; Fairfull-Smith, K. E.; Totsika, M. 10.1101/579896 — microbiology — Posted on 2019-03-16 1598 Identification of a novel gammaherpesvirus in Canada lynx (Lynx canadensis) Hendrikse, L. D.; Kambli, A.; Kayko, C.; Canuti, M.; Rodrigues, B.; Stevens, B.; Vashon, J.; Lang, A. S.; Needle, D. B.; Troyer, R. M. 10.1101/579607 — microbiology — Posted on 2019-03-16 1599 Two ecotype-related long non-coding RNAs in the environmental control of root growth Blein, T.; Balzergue, C.; Roule, T.; Gabriel, M.; Scalisi, L.; Sorin, C.; Christ, A.; Delannoy, E.; Martin-Magniette, M.-L.; Nussaume, L.; Hartmann, C.; Gautheret, D.; Desnos, T.; Crespi, M. 10.1101/579656 — plant biology — Posted on 2019-03-16 1600 Early patterns of functional brain development associated with autism spectrum disorder in tuberous sclerosis complex. Dickinson, A.; Varcin, K. J.; Sahin, M.; Nelson, C. A.; Jeste, S. S. 10.1101/578831 — neuroscience — Posted on 2019-03-16 1601 A Musashi-Related Protein Is Essential For Gametogenesis In Arabidopsis Moody, L. A.; Rabbinowitsch, E.; Dickinson, H. G.; Clayton, R.; Emms, D. M.; Langdale, J. 10.1101/579714 — plant biology — Posted on 2019-03-16 1602 The interaction of compliance and activation on the force-length operating range and force generating capacity of skeletal muscle Cox, S. M.; Easton, K. L.; Sanghvi, H.; Cromie Lear, M.; Marsh, R.; Delp, S.; Rubenson, J. 10.1101/580027 — physiology — Posted on 2019-03-16 1603 Simple, biologically informed models, but not convolutional neural networks describe target detection in naturalistic images Fruend, I. 10.1101/578633 — neuroscience — Posted on 2019-03-16 1604 Embodiment improves performance on an immersive brain computer interface in head-mounted virtual reality Juliano, J. M.; Spicer, R.; Lefebvre, S.; Jann, K.; Ard, T.; Santarnecchi, E.; Krum, D.; Liew, S.-L. 10.1101/578682 — neuroscience — Posted on 2019-03-16 1605 Relative Concentration of Brain Iron (rcFe) Derived from Standard Functional MRI. Colcombe, S. J.; Milham, M. P.; Mackay-Brandt, A.; Franco, A.; Castellanos, X.; Craddock, C.; Cloud, J. 10.1101/579763 — neuroscience — Posted on 2019-03-16 1606 Exploring the limitations of event-related potential measures in moving subjects. Case studies of four different technical modifications in ergometer rowing Hill, H. 10.1101/578534 — neuroscience — Posted on 2019-03-16 1607 Manipulation of Oscillatory Phase by Transcranial Alternating Current Stimulation Fiene, M.; Schwab, B. C.; Misselhorn, J.; Herrmann, C.; Schneider, T. R.; Engel, A. K. 10.1101/579631 — neuroscience — Posted on 2019-03-16 1608 Evidence of extensive intraspecific noncoding reshuffling in a 169-kb mitochondrial genome of a basidiomycetous fungus Lee, H.-H.; Ke, H.-M.; Lin, C.-Y. I.; Lee, J. J.; Chung, C.-L.; Tsai, I. J. 10.1101/579870 — evolutionary biology — Posted on 2019-03-16 1609 Targeting and Vaccine Durability Are Key for Population-level Impact and Cost-Effectiveness of a Pox-Protein HIV Vaccine Regimen in South Africa Selinger, C.; Bershteyn, A.; Dimitrov, D. T.; Adamson, B. J.; Revill, P.; Hallett, T. B.; Phillips, A.; Bekker, L.-G.; Rees, H.; Gray, G. 10.1101/459909 — epidemiology — Posted on 2019-03-16 1610 Contribution of private gardens to habitat availability, connectivity and conservation of the common pipistrelle in Paris Mimet, A.; Kerbiriou, C.; Simon, L.; Julien, J.-F.; Raymond, R. 10.1101/579227 — ecology — Posted on 2019-03-16 1611 pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive Choudhary, S. 10.1101/578500 — bioinformatics — Posted on 2019-03-16 1612 Constitutive differences in glucocorticoid responsiveness are related to divergent spatial information processing abilities Huzard, D.; Vouros, A.; Monari, S.; Astori, S.; Vasilaki, E.; Sandi, C. 10.1101/579508 — animal behavior and cognition — Posted on 2019-03-16 1613 The multicellular incoherent feedforward loop motif generates spatial patterns Rodriguez-Paton, A.; Regueira, M.; Daza-Garcia, J. 10.1101/579342 — synthetic biology — Posted on 2019-03-16 1614 LSO:Ce Inorganic Scintillators are Biocompatible with Neuronal and Circuit Function Bartley, A. F.; Abiraman, K.; Stewart, L. T.; Hossain, M. I.; Gahan, D. M.; Kamath, A. V.; Burdette, M. K.; Andrabe, S.; Foulger, S. H.; McMahon, L. L.; Dobrunz, L. E. 10.1101/579722 — neuroscience — Posted on 2019-03-16 1615 Lithium treatment reverses irradiation-induced changes in rodent neural progenitors Zanni, G.; Goto, S.; Gaudenzi, G.; Naidoo, V.; Levy, G.; Di Martino, E.; Dethlefsen, O.; Cedazo-Minguez, A.; Merino-Serrais, P.; Hermanson, O.; Blomgren, K. 10.1101/579235 — neuroscience — Posted on 2019-03-16 1616 Bayesian population receptive field modeling in human somatosensory cortex Puckett, A. M.; Bollmann, S.; Junday, K.; Barth, M.; Cunnington, R. 10.1101/577981 — neuroscience — Posted on 2019-03-16 1617 Flexible representation and memory of higher-dimensional cognitive variables with grid cells Klukas, M.; Lewis, M.; Fiete, I. 10.1101/578641 — neuroscience — Posted on 2019-03-16 1618 The speed of human social interaction perception Isik, L.; Mynick, A.; Pantazis, D.; Kanwisher, N. 10.1101/579375 — neuroscience — Posted on 2019-03-16 1619 Multiple Cross Displacement Amplification Coupled with Gold Nanoparticles-Based Lateral Flow Biosensor for Detection of the Mobilized Colistin Resistance Gene mcr-1 Gong, L.; Liu, E.; Che, J.; Li, J.; Liu, X.; Xu, H.; Liang, J. 10.1101/579904 — molecular biology — Posted on 2019-03-16 1620 Direct interaction of PIWI and DEPS-1 is essential for piRNA function and condensate ultrastructure in Caenorhabditis elegans Suen, K. M.; Braukmann, F.; Butler, R.; Bensaddek, D.; Akay, A.; Lin, C.-C.; Doshi, N.; Sapetschnig, A.; Lamond, A. I.; Ladbury, J. E.; Miska, E. A. 10.1101/580043 — cell biology — Posted on 2019-03-16 1621 The Work Performed By Biological Motors Baker, J. 10.1101/580241 — biophysics — Posted on 2019-03-16 1622 Transverse sinus injections: A novel method for whole-brain vector-driven gene delivery Hamodi, A. S.; Martinez Sabino, A.; Fitzgerald, N. D.; Crair, M. C. 10.1101/579730 — neuroscience — Posted on 2019-03-16 1623 5-methoxy-N,N-dimethyltryptamine: An ego-dissolving endogenous neurochemical catalyst of creativity Germann, C. B. 10.1101/578435 — neuroscience — Posted on 2019-03-16 1624 Adaptation to seasonal reproduction and thermal minima-related factors drives fine-scale divergence despite gene flow in Atlantic herring populations Fuentes-Pardo, A. P.; Bourne, C.; Singh, R.; Emond, K.; Pinkham, L.; McDermid, J. L.; Andersson, L.; Ruzzante, D. E. 10.1101/578484 — genomics — Posted on 2019-03-16 1625 Multiple genetic loci affect place learning and memory performance in Drosophila melanogaster Williams-Simon, P. A.; Posey, C.; Mitchell, S.; Ng'oma, E.; Mrkvicka, J.; Zars, T.; King, E. 10.1101/580092 — genetics — Posted on 2019-03-16 1626 Interpreting, forecasting, and controlling feeding behaviour using high-resolution data McGrath, T. M.; Spreckley, E.; Rodriguez, A. F.; Viscomi, C.; Alamshah, A.; Akalestou, E.; Murphy, K. G.; Jones, N. S. 10.1101/578344 — animal behavior and cognition — Posted on 2019-03-16 1627 ‘Normal’ hearing thresholds and fundamental auditory grouping processes predict difficulties with speech-in-noise perception Holmes, E.; Griffiths, T. 10.1101/578393 — neuroscience — Posted on 2019-03-16 1628 Sleep promotes relational overlapping memories for long-term generalization Matorina, N.; Poppenk, J. 10.1101/578492 — neuroscience — Posted on 2019-03-16 1629 Neurophysiological predictors of memory impairment in schizophrenia: decoupled slow-wave dynamics during non-REM sleep Bartsch, U.; Simpkin, A.; Demanuele, C.; Wamsley, E.; Marston, H.; Jones, M. W. 10.1101/578039 — neuroscience — Posted on 2019-03-16 1630 Phage-Encoded LuxR-Type Receptors Responsive to Host-Produced Bacterial Quorum-Sensing Autoinducers Silpe, J. E.; Bassler, B. L. 10.1101/577726 — microbiology — Posted on 2019-03-16 1631 Gut microbiota plasticity is correlated with sustained weight loss on a low-carb or low-fat dietary intervention Grembi, J. A.; Nguyen, L. H.; Haggerty, T. D.; Gardner, C. D.; Holmes, S. P.; Parsonnet, J. 10.1101/580217 — microbiology — Posted on 2019-03-16 1632 Proteomic Analysis of Plasmodium Merosomes: The Link Between Liver and Blood Stages in Malaria Shears, M. J.; Sekhar Nirujogi, R.; Swearingen, K. E.; Renuse, S.; Mishra, S.; Jaipal Reddy, P.; Moritz, R. L.; Pandey, A.; Sinnis, P. 10.1101/580266 — microbiology — Posted on 2019-03-16 1633 The actin-capping protein alpha-adducin is required for T-cell costimulation Thauland, T. J.; Butte, M. J. 10.1101/580191 — immunology — Posted on 2019-03-16 1634 Complete genome sequence and evolution analysis of Psychrobacter sp. YP14 from Gammaridea Gastrointestinal Microbiota of Yap Trench Wei, J.; Gao, Z.; Liu, W.; Chen, H. 10.1101/578518 — genomics — Posted on 2019-03-16 1635 Vps34/PIK3C3 deletion in thyroid impairs thyroid hormonogenesis and autophagic flux Grieco, G.; Wang, T.; Delcorte, O.; Janssens, V.; Spourquet, C.; Strickaert, A.; Gaide-Chevronnay, H.; Liao, X.-H.; Bilanges, B.; Refetoff, S.; Vanhaesebroeck, B.; Maenhaut, C.; Courtoy, P.; Pierreux, C. 10.1101/580142 — cell biology — Posted on 2019-03-16 1636 Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation Kelmer Sacramento, E.; Kirkpatrick, J. M.; Mazzetto, M.; Di Sanzo, S.; Caterino, C.; Sanguanini, M.; Papaevgeniou, N.; Lefaki, M.; Childs, D.; Bagnoli, S.; Terzibasi Tozzini, E.; Bartolome, A.; Romanov, N.; Baumgart, M.; Huber, W.; Chondrogianni, N.; Vendruscolo, M.; Cellerino, A.; Ori, A. 10.1101/577478 — systems biology — Posted on 2019-03-16 1637 Adenovirus serotype 26 utilises sialic acid bearing glycans as a primary cell entry receptor Baker, A. T.; Mundy, R.; Davies, J. A.; Rizkallah, P. J.; Parker, A. L. 10.1101/580076 — microbiology — Posted on 2019-03-16 1638 Separations-Encoded Microparticles For Single-Cell Western Blotting Gumuscu, B.; Herr, A. 10.1101/580233 — bioengineering — Posted on 2019-03-16 1639 Molecular signatures of the rediae, cercariae and adult worm stages in the complex life cycles of parasitic flatworms (Psilostomatidae, Trematoda) Nesterenko, M.; Starunov, V.; Shchenkov, S.; Maslova, A.; Denisova, S.; Granovich, A.; Dobrovolskij, A.; Khalturin, K. 10.1101/580225 — zoology — Posted on 2019-03-16 1640 Pyridox(am)ine 5’-phosphate oxidase deficiency induces seizures in Drosophila melanogaster Chi, W.; Iyengar, A.; Albersen, M.; Bosma, M.; Verhoeven-Duif, N. M.; Wu, C.-F.; Zhuang, X. 10.1101/580050 — neuroscience — Posted on 2019-03-16 1641 Prioritizing putatively etiological T cell epitopes across autoimmune diseases Ogishi, M. 10.1101/580126 — immunology — Posted on 2019-03-16 1642 How phenotypic convergence arises in experimental evolution Simoes, P.; Fragata, I.; Santos, J.; Santos, M. A.; Santos, M.; Rose, M. R.; Matos, M. 10.1101/579524 — evolutionary biology — Posted on 2019-03-16 1643 Genomic signatures of extreme body size divergence in baboons Chiou, K. L.; Bergey, C. M.; Burrell, A. S.; Disotell, T. R.; Rogers, J.; Jolly, C. J.; Phillips-Conroy, J. E. 10.1101/578740 — evolutionary biology — Posted on 2019-03-16 1644 Male recombination produced multiple geographically restricted neo-Y chromosome haplotypes of varying ages that correlate with onset of neo-Y decay in Drosophila albomicans Wei, K. H.-C.; Bachtrog, D. 10.1101/580118 — evolutionary biology — Posted on 2019-03-16 1645 The complete, functional and dynamic cycle of the bacterial Initiation Factor 3 Nakamoto, J. A.; Spurio, R.; Konevega, A. L.; Fabbretti, A.; Milon, P. 10.1101/579326 — biophysics — Posted on 2019-03-16 1646 The role of strigolactones in regulation of stomatal conductance and plant-pathogen interactions in Arabidopsis thaliana Kalliola, M.; Jakobson, L.; Davidsson, P.; Pennanen, V.; Waszczak, C.; Yarmolinsky, D.; Zamora, O.; Palva, E. T.; Kariola, T.; Kollist, H.; Brosche, M. 10.1101/573873 — plant biology — Posted on 2019-03-16 1647 Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single cell resolution: a focus on aging and cancer O'Hara, R.; Tedone, E.; Ludlow, A. T.; Huang, E.; Arosio, B.; Mari, D.; Shay, J. W. 10.1101/579789 — molecular biology — Posted on 2019-03-16 1648 Beyond SNP Heritability: Polygenicity and Discoverability of Phenotypes Estimated with a Univariate Gaussian Mixture Model Holland, D.; Frei, O.; Desikan, R.; Fan, C.-C.; Shadrin, A. A.; Smeland, O. B.; Sundar, V. S.; Thompson, P.; Andreassen, O. A.; Dale, A. M. 10.1101/133132 — genomics — Posted on 2019-03-16 1649 Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders Seidlitz, J.; Nadig, A.; Liu, S.; Bethlehem, R. A. I.; Vertes, P. E.; Morgan, S. E.; Vasa, F.; Romero-Garcia, R.; Lalonde, F. M.; Clasen, L. S.; Blumenthal, J. D.; Paquola, C.; Bernhardt, B.; Wagstyl, K.; Polioudakis, D.; de la Torre-Ubieta, L.; Geschwind, D. H.; Han, J. C.; Lee, N. R.; Murphy, D. G.; Bullmore, E. T.; Raznahan, A. 10.1101/573279 — neuroscience — Posted on 2019-03-16 1650 Chromatin arranges in filaments of blobs with nanoscale functional zonation Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L. 10.1101/566638 — genomics — Posted on 2019-03-16 1651 Spatial integration of mechanical forces by alpha-actinin establishes actin network symmetry. Senger, F.; Pitaval, A.; Ennomani, H.; Kurzawa, L.; Blanchoin, L.; Thery, M. 10.1101/578799 — cell biology — Posted on 2019-03-16 1652 Synchronization of sensory gamma oscillations promotes multisensory communication Misselhorn, J.; Schwab, B. C.; Schneider, T. R.; Engel, A. K. 10.1101/523688 — neuroscience — Posted on 2019-03-16 1653 Extinction-resistant attention to long-term conditioned threat is indexed by selective visuocortical alpha suppression in humans Panitz, C.; Keil, A.; Mueller, E. M. 10.1101/533141 — neuroscience — Posted on 2019-03-16 1654 Disentangling strictly self-serving mutations from win-win mutations in a mutualistic microbial community Hart, S. F.; Pineda, J. M. B.; Chen, C.-C.; Green, R.; Shou, W. 10.1101/530287 — microbiology — Posted on 2019-03-16 1655 Revealing multi-scale population structure in large cohorts Diaz-Papkovich, A.; Anderson-Trocme, L.; Gravel, S. 10.1101/423632 — genomics — Posted on 2019-03-16 1656 Evolutionary significance of structural segments trailing beta strand 5 and alpha helix 10 in the design of catalytically active NAL superfamily Prem Kumar, M. K.; Manoharan, P. 10.1101/505230 — evolutionary biology — Posted on 2019-03-16 1657 Disorder Atlas: web-based software for the proteome-based interpretation of intrinsic disorder predictions Vincent, M.; Schnell, S. 10.1101/060699 — bioinformatics — Posted on 2019-03-16 1658 Practice of Cardiac Auscultation: Clinical perspectives and its implications on computer aided diagnosis Mandal, S.; Martis, R. J.; Mandana, K.; Acharya, R. U.; Chatterjee, J.; Ray, A. K. 10.1101/013334 — bioengineering — Posted on 2019-03-16 1659 Genome-wide ancestry and introgression in a Zambian baboon hybrid zone Chiou, K. L.; Bergey, C. M.; Burrell, A. S.; Disotell, T. R.; Rogers, J.; Jolly, C. J.; Phillips-Conroy, J. E. 10.1101/578781 — evolutionary biology — Posted on 2019-03-16 1660 High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations Jung, J.; Grant, T.; Thomas, D. R.; Diehnelt, C. W.; Grigorieff, N.; Joshua-Tor, L. 10.1101/580167 — biophysics — Posted on 2019-03-16 1661 Age Differences in Hemispheric Lateralization in Spatial and Verbal Visual Working Memory Sander, M. C.; Maier, P. M.; Napiorkowski, N.; Finke, K.; Toellner, T.; Mueller, H. J.; Lindenberger, U.; Werkle-Bergner, M.; Wiegand, I. 10.1101/577858 — neuroscience — Posted on 2019-03-16 1662 EpiSAFARI: Sensitive detection of valleys in epigenetic signals for enhancing annotations of functional elements Harmanci, A. O.; Serin Harmanci, A.; Swaminathan, J.; Gopalakrishnan, V. 10.1101/579847 — bioinformatics — Posted on 2019-03-16 1663 Prenatal thyroid hormone exposure increases growth but not oxidative stress in a wild passerine species Sarraude, T.; Hsu, B.-Y.; Groothuis, T. G. G.; Ruuskanen, S. 10.1101/578047 — physiology — Posted on 2019-03-16 1664 Advantages of genotype imputation with ethnically matched reference panel for rare variant association analyses Kals, M.; Nikopensius, T.; Läll, K.; Pärn, K.; Sikka, T. T.; Suvisaari, J.; Salomaa, V.; Ripatti, S.; Palotie, A.; Metspalu, A.; Esko, T.; Palta, P.; Mägi, R. 10.1101/579201 — genomics — Posted on 2019-03-16 1665 Deep Learning with Multimodal Representation for Pancancer Prognosis Prediction Cheerla, A.; Gevaert, O. 10.1101/577197 — bioinformatics — Posted on 2019-03-16 1666 The Beacon Calculus: A formal method for the flexible and concise modelling of biological systems Boemo, M. A.; Cardelli, L.; Nieduszynski, C. A. 10.1101/579029 — systems biology — Posted on 2019-03-16 1667 Effect of Antimicrobial Peptides HNP-1 and hBD-1 on Staphylococcus aureus Clinical Strains in vitro and in vivo. Bolatchiev, A.; Baturin, V.; Bazikov, I.; Maltsev, A.; Kunitsina, E. 10.1101/578278 — pharmacology and toxicology — Posted on 2019-03-16 1668 Short-Term Synaptic Dynamics Control the Activity Phase of Neurons in an Oscillatory Network Martinez, D.; Anwar, H.; Bose, A.; Bucher, D.; Nadim, F. 10.1101/578617 — neuroscience — Posted on 2019-03-16 1669 Reward boosts neural coding of task rules to optimise cognitive flexibility Hall-McMaster, S.; Muhle-Karbe, P.; Myers, N.; Stokes, M. 10.1101/578468 — neuroscience — Posted on 2019-03-16 1670 THE HIDDEN REPERTOIRE OF BRAIN DYNAMICS AND DYSFUNCTION McIntosh, R.; Jirsa, V. 10.1101/578443 — neuroscience — Posted on 2019-03-16 1671 Evidence of decreased gap junction coupling between astrocytes and oligodendrocytes in the anterior cingulate cortex of depressed suicides Tanti, A.; Lutz, P.-E.; Kim, J. J.; O'Leary, L.; Turecki, G.; Mechawar, N. 10.1101/578807 — neuroscience — Posted on 2019-03-16 1672 Pan-filovirus one-step reverse transcription-polymerase chain reaction screening assay Kopp, K.; Smith, I.; Klein, R.; Todd, S.; Marsh, G. A.; Ward, A. 10.1101/579458 — molecular biology — Posted on 2019-03-16 1673 Interplay of primary bovine lymphocytes and Mycobacterium avium subsp. paratuberculosis shows distinctly different proteome changes and immune pathways in host-pathogen interaction Kleinwort, K. J. H.; Hauck, S. M.; Degroote, R. L.; Lutterberg, K.; Scholz, A. M.; Hoelzel, C.; Maertlbauer, E. P.; Deeg, C. A. 10.1101/578187 — immunology — Posted on 2019-03-16 1674 A draft genome sequence of the miniature parasitoid wasp, Megaphragma amalphitanum Nedoluzhko, A.; Sharko, F.; Le, B.; Tsygankova, S.; Boulygina, E.; Rastorguev, S.; Sokolov, A.; Rodriguez, F.; Mazur, A.; Polilov, A.; Benton, R.; Evgen'ev, M.; Arkhipova, I.; Prokhortchouk, E.; Skryabin, K. 10.1101/579052 — genomics — Posted on 2019-03-16 1675 High-Affinity Binding of Chemokine Analogs that Display Ligand Bias at the HIV-1 Co-receptor CCR5 Rico, C. A.; Berchiche, Y. A.; Horioka, M.; Peeler, J. C.; Lorenzen, E.; Tian, H.; Kazmi, M. A.; Furstenberg, A.; Gaertner, H.; Hartley, O.; Sakmar, T. P.; Huber, T. 10.1101/575795 — biophysics — Posted on 2019-03-16 1676 Systematic and comprehensive benchmarking of an exome sequencing based germline copy-number variant detection pipeline in a clinical setting Rajagoapalan, R.; Murrell, J.; Jayaraman, P.; Wu, C.; Luo, M.; Conlin, L. K. 10.1101/579755 — bioinformatics — Posted on 2019-03-16 1677 Evolutionary dynamics in structured populations under strong population genetic forces Feder, A. F.; Pennings, P. S.; Hermisson, J.; Petrov, D. A. 10.1101/579854 — evolutionary biology — Posted on 2019-03-16 1678 Applying continuous functional traits to large brown macroalgae: variation across tidal emersion and wave exposure gradients Cappelatti, L.; Mauffrey, A.; Griffin, J. N. 10.1101/577825 — ecology — Posted on 2019-03-16 1679 Metabolic reprogramming from glycolysis to amino acid utilization in cardiac HIF1α deficient mice. Menendez-Montes, I.; Escobar, B.; Palacios, B.; Gomez, M. J.; Bonzon, E.; Ferrarini, A.; Alonso, A. V.; Jimenez-Borreguero, L. J.; Vazquez, J.; Martin-Puig, S. 10.1101/579433 — developmental biology — Posted on 2019-03-16 1680 Human intestinal enteroids with inducible neurogenin-3 expression as a novel model of gut hormone secretion Chang-Graham, A. L.; Danhof, H. A.; Engevik, M. A.; Tomaro-Duchesneau, C.; Karandikar, U. C.; Estes, M. K.; Versalovic, J.; Britton, R. A.; Hyser, J. M. 10.1101/579698 — microbiology — Posted on 2019-03-16 1681 Primo: integration of multiple GWAS and omics QTL summary statistics for elucidation of molecular mechanisms of trait-associated SNPs and detection of pleiotropy in complex traits Gleason, K. J.; Yang, F.; Pierce, B.; He, X.; Chen, L. S. 10.1101/579581 — genomics — Posted on 2019-03-16 1682 Pervasive convergent evolution and extreme phenotypes define chaperone requirements of protein homeostasis Draceni, Y.; Pechmann, S. 10.1101/578724 — evolutionary biology — Posted on 2019-03-16 1683 Recent global changes have decoupled species richness from specialization patterns in North American birds Mimet, A.; Buitenwerf, R.; Sandel, B.; Svenning, J.-C.; Normand, S. 10.1101/577841 — ecology — Posted on 2019-03-16 1684 Estimation of Membrane Curvature for Cryo-Electron Tomography Kalemanov, M.; Collado, J. F.; Baumeister, W.; Fernandez-Busnadiego, R.; Martinez-Sanchez, A. 10.1101/579060 — bioinformatics — Posted on 2019-03-16 1685 Scalable image processing techniques for quantitative analysis of volumetric biological images from light-sheet microscopy Swaney, J.; Kamentsky, L.; Evans, N. B.; Xie, K.; Park, Y.-G.; Drummond, G.; Yun, D. H.; Chung, K. 10.1101/576595 — bioengineering — Posted on 2019-03-16 1686 Robustness and timing of cellular differentiation through population-based symmetry breaking Stanoev, A.; Schroeter, C.; Koseska, A. 10.1101/578898 — systems biology — Posted on 2019-03-16 1687 Pax6 and KDM5C co-occupy a subset of developmentally critical genes including Notch signaling regulators in neural progenitors Gaudenzi, G.; Dethlefsen, O.; Walfridsson, J.; Hermanson, O. 10.1101/579219 — molecular biology — Posted on 2019-03-16 1688 Microbiological, biochemical, physicochemical surface properties and biofilm forming ability of Brettanomyces bruxellensis Dimopoulou, M.; Renault, M.; Dols-Lafargue, M.; Albertin, W.; Herry, J.-M.; Bellon-Fontaine, M.-N.; Masneuf-Pomarede, I. 10.1101/579144 — microbiology — Posted on 2019-03-16 1689 Depiction of secondary metabolites and antifungal activity of Bacillus velezensis DTU001 Devi, S.; Kiesewalter, H. T.; Kovacs, R.; Frisvad, J.; Weber, T.; Larsen, T. O.; Kovacs, A. T.; Ding, L. 10.1101/577817 — microbiology — Posted on 2019-03-16 1690 Blood cells of adult Drosophila do not expand, but control survival after bacterial infection by induction of Drosocin around their reservoir at the respiratory epithelia Sanchez Bosch, P.; Makhijani, K.; Herboso, L.; Gold, K. S.; Baginsky, R.; Woodcock, K. J.; Alexander, B.; Kukar, K.; Corcoran, S.; Ouyang, D.; Wong, C.; Ramond, E. J.; Rhiner, C.; Moreno, E.; Lemaitre, B.; Geissmann, F.; Brueckner, K. 10.1101/578864 — immunology — Posted on 2019-03-16 1691 Proteome-wide signatures of function in highly diverged intrinsically disordered regions Zarin, T.; Strome, B.; Nguyen Ba, A. N.; Alberti, S.; Forman-Kay, J.; Moses, A. M. 10.1101/578716 — genomics — Posted on 2019-03-16 1692 Balancing selection shapes the Intracellular Pathogen Response in natural Caenorhabditis elegans populations van Sluijs, L.; Bosman, K. J.; Pankok, F.; Blokhina, T.; Riksen, J. A. G.; Snoek, B.; Pijlman, G. P.; Kammenga, J. E.; Sterken, M. G. 10.1101/579151 — genetics — Posted on 2019-03-16 1693 The Origin and Early Evolution of the Legumes are a Complex Paleopolyploid Phylogenomic Tangle closely associated with the Cretaceous-Paleogene (K-Pg) Boundary Koenen, E.; Ojeda, D.; Steeves, R.; Migliore, J.; Bakker, F.; Wieringa, J.; Kidner, C.; Hardy, O.; Pennington, T.; Herendeen, P.; Bruneau, A.; Hughes, C. 10.1101/577957 — evolutionary biology — Posted on 2019-03-16 1694 ProtCID: A tool for hypothesis generation of the structures of protein interactions Xu, Q.; Dunbrack, R. L. 10.1101/579862 — bioinformatics — Posted on 2019-03-16 1695 Higher order analysis of gene correlations by tensor decomposition Yahyanejad, F. 10.1101/579276 — bioinformatics — Posted on 2019-03-16 1696 treeClust improves protein co-regulation analysis due to robust selectivity for close linear relationships Kustatscher, G.; Grabowski, P.; Rappsilber, J. 10.1101/578971 — systems biology — Posted on 2019-03-16 1697 An approximate derivate-based controller for regulating gene expression Modi, S.; Dey, S.; Singh, A. 10.1101/579615 — synthetic biology — Posted on 2019-03-16 1698 High angular resolution diffusion MRI reveals conserved and deviant programs in the paths that guide human cortical circuitry Charvet, C. J.; Das, A.; Song, J. W.; Tindall-Burgess, D. J.; Kabaria, P.; Dai, G.; Kane, T.; Takahashi, E. 10.1101/576967 — neuroscience — Posted on 2019-03-16 1699 Cannabis-associated symptom profiles in patients with first episode psychosis and population controls Quattrone, D.; Ferraro, L.; Tripoli, G.; La Cascia, E.; Quigley, H.; EU-GEI WP2 group, ; Gayer-Anderson, C.; Jones, P. B.; Kirkbride, J. B.; La Barbera, D.; Tarricone, I.; Lynskey, M. T.; Freeman, T. P.; Sham, P. C.; Cardno, A.; Vassos, E.; van Os, J.; Morgan, C.; Reininghaus, U.; Lewis, C. M.; Murray, R. M.; Di Forti, M. 10.1101/577932 — neuroscience — Posted on 2019-03-16 1700 Host metabolic reprogramming of Pseudomonas aeruginosa by phage-based quorum sensing modulation Hendrix, H.; Kogadeeva, M.; Zimmermann, M.; Sauer, U.; De Smet, J.; Muchez, L.; Lissens, M.; Staes, I.; Voet, M.; Wagemans, J.; Ceyssens, P.-J.; Noben, J.-P.; Aertsen, A.; Lavigne, R. 10.1101/577908 — microbiology — Posted on 2019-03-16 1701 Eye in a Disk: eyeIntegration human pan-eye and body transcriptome database version 1.0 Swamy, V.; McGaughey, D. 10.1101/579482 — genomics — Posted on 2019-03-16 1702 Is evolution predictable? Quantitative genetics under complex genotype-phenotype maps Milocco, L.; Salazar-Ciudad, I. 10.1101/578021 — evolutionary biology — Posted on 2019-03-16 1703 Resilience Analysis for Competing Populations Cesar Fassoni, A.; de Carvalho Braga, D. 10.1101/578609 — ecology — Posted on 2019-03-16 1704 Embryonic geometry underlies phenotypic variation in decanalized conditions Huang, A.; Saunders, T. E. 10.1101/579623 — developmental biology — Posted on 2019-03-16 1705 Inferring biophysical models of evolution from genome-wide patterns of codon usage Kion-Crosby, W. B.; Manhart, M.; Morozov, A. V. 10.1101/578815 — biophysics — Posted on 2019-03-16 1706 Molecular Predicting Drought Tolerance in Maize Inbred Lines by Machine Learning Approaches Beiki, A. H. 10.1101/578880 — bioinformatics — Posted on 2019-03-16 1707 Hearing impairment due to Mir183/96/182 mutations suggests both loss and gain of function effects Lewis, M. A.; Di Domenico, F.; Ingham, N. J.; Prosser, H. M.; Steel, K. P. 10.1101/579003 — systems biology — Posted on 2019-03-16 1708 Efficient parameterization of large-scale dynamic models based on relative measurements Schmiester, L.; Schaelte, Y.; Froehlich, F.; Hasenauer, J.; Weindl, D. 10.1101/579045 — systems biology — Posted on 2019-03-16 1709 Epistatic Networks Associated with Parent-of-Origin Effects on Metabolic Traits Macias-Velasco, J. F.; St. Pierre, C. L.; Wayhart, J. P.; Yin, L.; Spears, L.; Funai, K.; Cheverud, J. M.; Semenkovich, C. F.; Lawson, H. A. 10.1101/579748 — systems biology — Posted on 2019-03-16 1710 Marine sediments illuminate Chlamydiae diversity and evolution Dharamshi, J.; Tamarit, D.; Eme, L.; Stairs, C.; Martijn, J.; Homa, F.; Jorgensen, S.; Spang, A.; Ettema, T. J. G. 10.1101/577767 — microbiology — Posted on 2019-03-16 1711 Myosin II isoforms play distinct roles in adherens junction biogenesis Ladoux, B.; Mege, R.-M.; Dang, T.; Heuze, M.; Van Hest, J.; Sankara, G.; Marcq, P.; D'Alessandro, J.; Cellerin, V.; Williams, D. S. 10.1101/578997 — cell biology — Posted on 2019-03-16 1712 Gene Expression Mediated Antiproliferative Potential and Safety of Selected Medicinal Plants Against Cancerous and Normal Cells MBUGUA, R. W.; Mwitari, P. G.; Njagi, E. M.; Ngule, C. M. 10.1101/578948 — cancer biology — Posted on 2019-03-16 1713 Gender differences in attitudes toward death among Chinese university students: A survey in hunan and Heilongjiang province Wang, Y.; Tang, S.; Hu, X.; Qin, C.; Ma, L.; Li, Y.; Khoshnood, K.; Sun, M. 10.1101/578955 — scientific communication and education — Posted on 2019-03-16 1714 Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma Megquier, K.; Turner-Maier, J.; Swofford, R.; Kim, J.-H.; Sarver, A. L.; Wang, C.; Sakthikumar, S.; Johnson, J.; Koltookian, M.; Lewellen, M.; Scott, M. C.; Graef, A. J.; Borst, L.; Tonomura, N.; Alfoldi, J.; Painter, C.; Thomas, R.; Karlsson, E. K.; Breen, M.; Modiano, J. F.; Elvers, I.; Lindblad-Toh, K. 10.1101/570879 — genomics — Posted on 2019-03-15 1715 Changes in gene expression shift and switch genetic interactions Li, X.; Lalic, J.; Baeza-Centurion, P.; Dhar, R.; Lehner, B. 10.1101/578419 — genetics — Posted on 2019-03-15 1716 Cingulate Cortex Atrophy is Associated with Hearing Loss in Presbycusis with Cochlear Amplifier Dysfunction Belkhiria, C.; Vergara, R. C.; San Martin, S.; Leiva, A.; Marcenaro, B.; Martinez, M.; Delgado, C.; Delano, P. H. 10.1101/574228 — neuroscience — Posted on 2019-03-15 1717 Timing and Duration of Gbx2 Expression Delineates Thalamocortical and Dopaminergic Medial Forebrain Bundle Circuitry Normand, E. A.; Browning, C.; Zervas, M. 10.1101/579664 — neuroscience — Posted on 2019-03-15 1718 Comprehensive mutation profiling of both cfDNA and CTCs in gynecological cancer patients Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Chae, C. H.; Bhak, J.; Kim, B. C.; Cho, D.-H. 10.1101/566786 — genetics — Posted on 2019-03-15 1719 The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology Hahn, I.; Voelzmann, A.; Liew, Y.-T.; Costa-Gomes, B.; Prokop, A. 10.1101/577320 — cell biology — Posted on 2019-03-15 1720 Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts Lerche, M.; Elosegui-Artola, A.; Guzman, C.; Georgiadou, M.; Kechagia, J. Z.; Gulberg, D.; Roca-Cusachs, P.; Peuhu, E.; Ivaska, J. 10.1101/570721 — cell biology — Posted on 2019-03-15 1721 Branching developmental pathways through high dimensional single cell analysis in trajectory space Dermadi, D.; Bscheider, M.; Bjegovic, K.; Lazarus, N. H.; Szade, A.; Hadeiba, H.; Butcher, E. C. 10.1101/336313 — bioinformatics — Posted on 2019-03-15 1722 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y. 10.1101/567891 — bioinformatics — Posted on 2019-03-15 1723 Effects of dietary taurine level on visual function in European sea bass (Dicentrarchus labrax) Brill, R.; Horodysky, A.; Place, A.; Larkin, M.; Reimschuessel, R. 10.1101/577023 — physiology — Posted on 2019-03-15 1724 Studies of allosteric coupling in KcsA using a constitutively open mutant Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E. 10.1101/567024 — biophysics — Posted on 2019-03-15 1725 Object Detection Networks and Augmented Reality for Cellular Detection in Fluorescence Microscopy Acquisition and Analysis. Waithe, D.; Brown, J. M.; Reglinski, K.; Diez-Sevilla, I.; Roberts, D.; Eggeling, C. 10.1101/544833 — bioinformatics — Posted on 2019-03-15 1726 The sequence of the extruded non-template strand determines the architecture of R-loops. Carrasco-Salas, Y.; Malapert, A.; Sulthana, S.; Molcrette, B.; Chazot-Franguiadakis, L.; Bernard, P.; Chedin, F.; Faivre-Moskalenko, C.; Vanoosthuyse, V. 10.1101/576561 — molecular biology — Posted on 2019-03-15 1727 Evaluating potential drug targets through human loss-of-function genetic variation Minikel, E. V.; Karczewski, K. J.; Martin, H. C.; Cummings, B. B.; Whiffin, N.; Alfoldi, J.; Trembath, R. C.; van Heel, D. A.; Daly, M. J.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; Schreiber, S. L.; MacArthur, D. G. 10.1101/530881 — genomics — Posted on 2019-03-15 1728 The Patchy Distribution of Restriction-Modification System Genes and the Conservation of Orphan Methyltransferases in Halobacteria. Fullmer, M. S.; Ouellette, M.; Louyakis, A.; Papke, R. T.; Gogarten, J. P. 10.1101/551721 — genomics — Posted on 2019-03-15 1729 Chromatin arranges in filaments of blobs with nanoscale functional zonation Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L. 10.1101/566638 — genomics — Posted on 2019-03-15 1730 Pattern separation is the key driver of expectation-modulated memory Frank, D.; Montaldi, D. 10.1101/577791 — neuroscience — Posted on 2019-03-15 1731 SpectralTAD: an R package for defining a hierarchy of Topologically Associated Domains using spectral clustering Cresswell, K. G.; Stansfield, J. C.; Dozmorov, M. G. 10.1101/549170 — bioinformatics — Posted on 2019-03-15 1732 Constructing a Draft Map of the Cannabis Proteome Jenkins, C.; Orsburn, B. 10.1101/577635 — plant biology — Posted on 2019-03-15 1733 Effectiveness and selectivity of a heroin conjugate vaccine to attenuate heroin, 6-acetylmorphine, and morphine antinociception in rats: Comparison with naltrexone Schwienteck, K. L.; Blake, S.; Bremer, P. T.; Poklis, J. L.; Townsend, E. A.; Negus, S. S.; Banks, M. L. 10.1101/577494 — pharmacology and toxicology — Posted on 2019-03-15 1734 Resolving multisensory and attentional influences across cortical depth in sensory cortices Gau, R.; Bazin, P.-L.; Trampel, R.; Turner, R.; Noppeney, U. 10.1101/548933 — neuroscience — Posted on 2019-03-15 1735 HiLDA: a statistical approach to investigate differences in mutational signatures Yang, Z.; Pandey, P.; Shibata, D.; Conti, D. V.; Marjoram, P.; Siegmund, K. 10.1101/577452 — genomics — Posted on 2019-03-15 1736 Neural population dynamics in prefrontal cortex and hippocampus during paired-associate learning Liu, Y.; Brincat, S. L.; Miller, E. K.; Hasselmo, M. E. 10.1101/578849 — neuroscience — Posted on 2019-03-15 1737 Social hierarchy regulates ocular dominance plasticity in adult male mice. Balog, J.; Hintz, F.; Isstas, M.; Teichert, M.; Winter, C.; Lehmann, K. 10.1101/579169 — neuroscience — Posted on 2019-03-15 1738 A Drosophila model of neuronal ceroid lipofuscinosis CLN4 reveals a hypermorphic gain of function mechanism Imler, E.; Pyon, J. S.; Kindelay, S.; Zhang, Y.-q.; Chandra, S. S.; Zinsmaier, K. E. 10.1101/579771 — neuroscience — Posted on 2019-03-15 1739 Timing and Duration of Gbx2 Expression Delineates Thalamocortical and Dopaminergic Medial Forebrain Bundle Circuitry Normand, E. A.; Browning, C.; Zervas, M. 10.1101/579664 — neuroscience — Posted on 2019-03-15 1740 ESCRT-III/Vps4 controls heterochromatin-nuclear envelope attachments Pieper, G. H.; Sprenger, S.; Teis, D.; Oliferenko, S. 10.1101/579805 — cell biology — Posted on 2019-03-15 1741 Hypothalamic-extended amygdala circuit regulates temporal discounting Rossi, M.; Li, H.; Watson, G.; Moore, H. G.; Cai, M. T. T.; Kim, N.; Vokt, K.; Lu, D.; Bartholomew, R.; Yin, H. 10.1101/577973 — neuroscience — Posted on 2019-03-15 1742 Simple Framework for Constructing Functional Spiking Recurrent Neural Networks Kim, R.; Li, Y.; Sejnowski, T. J. 10.1101/579706 — neuroscience — Posted on 2019-03-15 1743 Effects of transcranial alternating-current stimulation to secondary motor areas on cortical oscillations in stroke patients Krawinkel, L. A.; Boenstrup, M.; Feldheim, J. F.; Schulz, R.; Backhaus, W.; Schneider, T. R.; Misselhorn, J.; Cheng, B.; Gerloff, C. 10.1101/529818 — neuroscience — Posted on 2019-03-15 1744 An EDS1-SAG101 complex functions in TNL-mediated immunity in Solanaceae Gantner, J.; Ordon, J.; Kretschmer, C.; Guerois, R.; Stuttmann, J. 10.1101/511956 — plant biology — Posted on 2019-03-15 1745 A dynamic neural network model for predicting risk of Zika in real-time Akhtar, M.; Kraemer, M. U.; Gardner, L. 10.1101/466581 — epidemiology — Posted on 2019-03-15 1746 Hundreds of yeast mRNAs form a separately addressable, translation elongation-controlled regulon Kazana, E.; von der Haar, T. 10.1101/513705 — molecular biology — Posted on 2019-03-15 1747 Cyto-architecture constrains a photoactivation induced tubulin gradient in the syncytial Drosophila embryo Thukral, S.; Kaity, B.; Dey, B.; Sharma, S.; Nandi, A.; Mitra, M.; Rikhy, R. 10.1101/520031 — developmental biology — Posted on 2019-03-15 1748 Follicle-stimulating hormone and luteinizing hormone increase Ca2+ in the granulosa cells of mouse ovarian follicles Egbert, J. R.; Fahey, P. G.; Reimer, J.; Owen, C. M.; Evsikov, A. V.; Nikolaev, V. O.; Griesbeck, O.; Ray, R. S.; Tolias, A. S.; Jaffe, L. A. 10.1101/520122 — cell biology — Posted on 2019-03-15 1749 Comparative assessment of long-read error-correction software applied to RNA-sequencing data Ishi Soares de Lima, L.; Marchet, C.; Caboche, S.; Da Silva, C.; Istace, B.; Aury, J.-M.; Touzet, H.; Chikhi, R. 10.1101/476622 — bioinformatics — Posted on 2019-03-15 1750 Structural insights into substrate recognition by the SOCS2 E3 ubiquitin ligase Kung, W.-W.; Ramachandran, S.; Makukhin, N.; Bruno, E.; Ciulli, A. 10.1101/470187 — biochemistry — Posted on 2019-03-15 1751 Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response Szewczyk, M. M.; Ishikawa, Y.; Organ, S.; Sakai, N.; Li, F.; Ackloo, S.; Eram, M. S.; Dilworth, D.; Fukushi, H.; Harding, R.; dela Sena, C. C.; Sugo, T.; Hayashi, K.; Macleod, D.; Zepeda, C.; Takagi, S.; Al-Awar, R.; Richard, S.; Takizawa, M.; Arrowsmith, C. H.; Vedadi, M.; Brown, P. J.; Nara, H.; Barsyte-Lovejoy, D. 10.1101/503136 — biochemistry — Posted on 2019-03-15 1752 The conflict between adaptation and dispersal for maintaining biodiversity in changing environments Thompson, P. L.; Fronhofer, E. A. 10.1101/490722 — ecology — Posted on 2019-03-15 1753 TFIIIC binding to Alu elements controls gene expression via chromatin looping and histone acetylation Ferrari, R.; Llobet Cucalon, L. I.; Di Vona, C.; Le Dilly, F.; Vidal, E.; Lioutas, A.; Oliete, J. Q.; Jochem, L.; Cutts, E.; Dieci, G.; Alessandro, V.; Teichmann, M.; de la Luna, S.; Beato, M. 10.1101/455733 — genomics — Posted on 2019-03-15 1754 Contractile acto-myosin network on nuclear envelope remnants positions human chromosomes for mitosis Booth, A. J.; Yue, Z.; Eykelenboom, J. K.; Stiff, T.; Luxton, G. G.; Hochegger, H.; Tanaka, T. U. 10.1101/459750 — cell biology — Posted on 2019-03-15 1755 pyMeSHSim: an integrative python package to realize biomedical named entity recognition, normalization and comparison Luo, Z.-H.; Shi, M.-W.; Yang, Z.; Zhang, H.-Y.; Chen, Z.-X. 10.1101/459172 — bioinformatics — Posted on 2019-03-15 1756 Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling Overton, I. M.; Sims, A. H.; Owen, J. A.; Heale, B.; Ford, M. J.; Lubbock, A. L. R.; Pairo-Castineira, E.; Essafi, A. 10.1101/455709 — systems biology — Posted on 2019-03-15 1757 A comprehensive framework to capture the arcana of neuroimaging analysis Close, T. G.; Ward, P. G. D.; Sforazzini, F.; Goscinski, W.; Chen, Z.; Egan, G. 10.1101/447649 — bioinformatics — Posted on 2019-03-15 1758 PathMe: Merging and exploring mechanistic pathway knowledge Domingo-Fernandez, D.; Mubeen, S.; Marin-Llao, J.; Hoyt, C.; Hofmann-Apitius, M. 10.1101/451625 — bioinformatics — Posted on 2019-03-15 1759 The influence of fluctuating population densities on evolutionary dynamics Pisa, H.; Hermisson, J.; Polechova, J. 10.1101/444273 — evolutionary biology — Posted on 2019-03-15 1760 Adjustment for index event bias in genome-wide association studies of subsequent events Dudbridge, F.; Allen, R. J.; Sheehan, N. A.; Schmidt, A. F.; Lee, J. C.; Jenkins, R. G.; Wain, L. V.; Hingorani, A. D.; Patel, R. S. 10.1101/436063 — epidemiology — Posted on 2019-03-15 1761 Assessment of risk to hoary squash bees (Peponapis pruinosa) and other ground-nesting bees from systemic insecticides in agricultural soil Willis Chan, D. S.; Prosser, R. S.; Rodriguez Gil, J. L.; Raine, N. E. 10.1101/434498 — ecology — Posted on 2019-03-15 1762 scRNA-seq mixology: towards better benchmarking of single cell RNA-seq analysis methods Tian, L.; Dong, X.; Freytag, S.; Le Cao, K.-A.; Su, S.; JalalAbadi, A.; Amann-Zalcenstein, D.; Weber, T. S.; Seidi, A.; Jabbari, J. S.; Naik, S.; Ritchie, M. E. 10.1101/433102 — bioinformatics — Posted on 2019-03-15 1763 Using optically-pumped magnetometers to measure magnetoencephalographic signals in the human cerebellum Lin, C.-H.; Tierney, T. M.; Holmes, N.; Boto, E.; Leggett, J.; Bestmann, S.; Bowtell, R.; Brookes, M. J.; Miall, R. C.; Barnes, G. R. 10.1101/425447 — neuroscience — Posted on 2019-03-15 1764 Human cortical neural stem cells generate regional organizer states in vitro before committing to excitatory neuronal fates Micali, N.; Kim, S.-K.; Diaz-Bustamante, M.; Stein-O'Brien, G.; Seo, S.; Shin, J.-H.; Rash, B. G.; Ma, S.; Olivares, N. A.; Arellano, J.; Maynard, K. R.; Fertig, E. J.; Cross, A. J.; Burli, R.; Brandon, N. J.; Weinberger, D. R.; Chenoweth, J. G.; Hoeppner, D. J.; Sestan, N.; Rakic, P.; Colantuoni, C.; McKay, R. D. 10.1101/577544 — neuroscience — Posted on 2019-03-15 1765 Computational estimation of ms-sec atomistic folding times Adhikari, U.; Mostofian, B.; Copperman, J.; Petersen, A.; Zuckerman, D. M. 10.1101/427393 — biophysics — Posted on 2019-03-15 1766 Dissociating refreshing and elaboration and their impacts on memory Bartsch, L. M.; Loaiza, V. M.; Jäncke, L.; Oberauer, K.; Lewis-Peacock, J. 10.1101/423277 — neuroscience — Posted on 2019-03-15 1767 Neuronal programming by microbiota enables environmental regulation of intestinal motility Obata, Y.; Boeing, S.; Castano, A.; Carina Bon-Frauches, A.; Gomez de Aguero, M.; Boesmans, W.; Yilmaz, B.; Lopes, R.; Huseynova, A.; Maradana, M. R.; Vanden Berghe, P.; Murray, A. J.; Stockinger, B.; Macpherson, A. J.; Pachnis, V. 10.1101/579250 — neuroscience — Posted on 2019-03-15 1768 Single cell expression variability in highly homogeneous populations of human cells is widespread, is heritable, and implies cell function Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J. 10.1101/574426 — genomics — Posted on 2019-03-15 1769 Network analysis of whole-brain fMRI dynamics: A new framework based on dynamic communicability Gilson, M.; Kouvaris, N. E.; Deco, G.; Mangin, J.-F.; Poupon, C.; Lefranc, S.; Riviere, D.; Zamora-Lopez, G. 10.1101/421883 — neuroscience — Posted on 2019-03-15 1770 The joint evolution of lifespan and self-fertilisation Lesaffre, T.; Billiard, S. 10.1101/420877 — evolutionary biology — Posted on 2019-03-15 1771 Theory on the looping mediated stochastic propulsion of transcription factors along DNA Murugan, R. 10.1101/418947 — biophysics — Posted on 2019-03-15 1772 Systematic analysis of the Myxococcus xanthus developmental gene regulatory network supports posttranslational regulation of FruA by C-signaling Saha, S.; Patra, P.; Igoshin, O.; Kroos, L. 10.1101/415331 — molecular biology — Posted on 2019-03-15 1773 Synergy of Topoisomerase and Structural-Maintenance-of Chromosomes Proteins Creates a Universal Pathway to Simplify Genome Topology Orlandini, E.; Marenduzzo, D.; Michieletto, D. 10.1101/410019 — biophysics — Posted on 2019-03-15 1774 Deep Learning of Representations for Transcriptomics-based Phenotype Prediction Smith, A. M.; Walsh, J. R.; Long, J.; Davis, C. B.; Henstock, P.; Hodge, M. R.; Maciejewski, M.; Mu, X. J.; Ra, S.; Zhao, S.; Ziemek, D.; Fisher, C. K. 10.1101/574723 — bioinformatics — Posted on 2019-03-15 1775 Fine-grained mapping of cortical somatotopies in chronic Complex Regional Pain Syndrome Mancini, F.; Wang, A. P.; Shira, M. M.; Isherwood, Z. J.; McAuley, J. H.; Iannetti, G.; Sereno, M. I.; Moseley, L.; Rae, C. D. 10.1101/409094 — neuroscience — Posted on 2019-03-15 1776 Sensitivity of Olfactory Sensory Neurons to food cues is tuned to nutritional states by Neuropeptide Y signalling Kaniganti, T.; Deogade, A.; Maduskar, A.; Mukherjee, A.; Guru, A.; Subhedar, N.; Ghose, A. 10.1101/573170 — neuroscience — Posted on 2019-03-15 1777 A Chromosome-level Sequence Assembly Reveals the Structure of the Arabidopsis thaliana Nd-1 Genome and its Gene Set Pucker, B.; Holtgraewe, D.; Stadermann, K. B.; Frey, K.; Huettel, B.; Reinhardt, R.; Weisshaar, B. 10.1101/407627 — genomics — Posted on 2019-03-15 1778 Somatic mutations in miRNA genes in lung cancer - potential functional consequences of non-coding sequence variants Galka-Marciniak, P.; Urbanek-Trzeciak, M. O.; Nawrocka, P. M.; Dutkiewicz, A.; Giefing, M.; Lewandowska, M. A.; Kozlowski, P. 10.1101/579011 — genomics — Posted on 2019-03-15 1779 Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder. Nagy, C.; Maitra, M.; Tanti, A.; Suderman, M.; Theroux, J.-F.; Mechawar, N.; Ragoussis, J.; Turecki, G. 10.1101/384479 — neuroscience — Posted on 2019-03-15 1780 Jomon genome sheds light on East Asian population history Gakuhari, T.; Nakagome, S.; Rasumussen, S.; Allentoft, M.; Sato, T.; Korneliussen, T.; Chuinneagain, B. N.; Matsumae, H.; Koganebuchi, K.; Schmidt, R.; Mizushima, S.; Kondo, O.; Shigehara, N.; Yoneda, M.; Kimura, R.; Ishida, H.; Masuyama, Y.; Yamada, Y.; Tajima, A.; Shibata, H.; Toyoda, A.; Tsurumoto, T.; Wakebe, T.; Shitara, H.; Hanihara, T.; Willerslev, E.; Sikora, M.; Oota, H. 10.1101/579177 — genomics — Posted on 2019-03-15 1781 Sympatric versus allopatric evolutionary contexts shape differential immune response in Biomphalaria / Schistosoma interaction. Portet, A.; Pinaud, S.; Chaparro, C.; Galinier, R.; Dheilly, N. M.; Charriere, G.; Allienne, J.-F.; Duval, D.; Gourbal, B. 10.1101/378034 — immunology — Posted on 2019-03-15 1782 Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release Egger, K.; Dau, T.; Epp, B. 10.1101/575720 — neuroscience — Posted on 2019-03-15 1783 Locus coeruleus integrity preserves memory performance across the adult life span Dahl, M. J.; Mather, M.; Duezel, S.; Bodammer, N. C.; Lindenberger, U.; Kuehn, S.; Werkle-Bergner, M. 10.1101/332098 — neuroscience — Posted on 2019-03-15 1784 Zinc intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC Lefrancois, L. H.; Kalinina, V.; Cardenal-Munoz, E.; Hanna, N.; Koliwer-Brandl, H.; Appiah, J.; Leuba, F.; Hilbi, H.; Soldati, T.; Barisch, C. 10.1101/575217 — cell biology — Posted on 2019-03-15 1785 Impression cytology is a non-invasive and effective method for ocular cell obtention from babies with Congenital Zika Syndrome: perspectives in OMIC studies. Barbosa, R. H.; dos Santos, M. L. B.; Silva, T. P.; Rosa-Fernandes, L.; Pinto, A.; Spinola, P.; Bonvicino, C.; Valverde, P.; Lucena, E.; Palmisano, G.; Melo, R.; Cardoso, C.; Lemos, B. 10.1101/577668 — molecular biology — Posted on 2019-03-15 1786 Direct proteolytic control of an extracytoplasmic function RNA polymerase sigma factor Bilyk, B.; Kim, S.; Baker, T. A.; Seipke, R. F. 10.1101/576462 — microbiology — Posted on 2019-03-15 1787 Unbiased metagenomic sequencing for pediatric meningitis in Bangladesh reveals neuroinvasive Chikungunya virus outbreak and other unrealized pathogens Saha, S.; Ramesh, A.; Kalantar, K. L.; Malaker, R.; Hasanuzzaman, M.; Khan, L. M.; Mayday, M. Y.; Sajib, M. S. I.; Li, L. M.; Langelier, C.; Rahman, H.; Crawford, E. D.; Tato, C. M.; Islam, M.; Juan, Y.-F.; Bourcy, C. d.; Dimitrov, B.; Wang, J.; Tang, J.; Sheu, J.; Egger, R.; Carvalho, T. R. D.; Wilson, M. R.; Saha, S.; DeRisi, J. 10.1101/579532 — genomics — Posted on 2019-03-15 1788 Development of behavioral modernity by hominins around 70,000 years ago was associated with simultaneous acquisition of a novel component of imagination, called prefrontal synthesis, and conversion of a preexisting rich-vocabulary non-recursive communication system to a fully recursive syntactic language Vyshedskiy, A. 10.1101/166520 — evolutionary biology — Posted on 2019-03-15 1789 Zika virus seroprevalence declines and neutralization antibodies wane in adults following outbreaks in French Polynesia and Fiji Henderson, A. D.; Aubry, M.; Kama, M.; Vanhomwegen, J.; Teissier, A.; Mariteragi-Helle, T.; Paoaafaite, T.; Manuguerra, J.-C.; Edmunds, J.; Whitworth, J.; Watson, C. H.; Lau, C. L.; Cao-Lormeau, V.-M.; Kucharski, A. J. 10.1101/578211 — epidemiology — Posted on 2019-03-15 1790 Spatial integration of mechanical forces by alpha-actinin establishes actin network symmetry. Senger, F.; Pitaval, A.; Ennomani, H.; Kurzawa, L.; Blanchoin, L.; Thery, M. 10.1101/578799 — cell biology — Posted on 2019-03-15 1791 Reduced insulin and IGF-1 signalling synergistically extend healthspan in male mice Walker, A. M. N.; Watt, N. T.; Warmke, N.; Yuldasheva, N. Y.; Drozd, M.; Haywood, N. J.; Skromna, A.; Makava, N.; Wheatcroft, S. B.; Kearney, M. T.; Cubbon, R. M. 10.1101/579110 — cell biology — Posted on 2019-03-15 1792 Rapid light-dependent degradation of fluorescent dyes in chemically-defined media Morawski, P. A.; Motley, S.; Campbell, D. 10.1101/578856 — cell biology — Posted on 2019-03-15 1793 Tricalbin-mediated contact sites control ER curvature to maintain plasma membrane integrity Collado, J.; Kalemanov, M.; Martinez-Sanchez, A.; Campelo, F.; Baumeister, W.; Stefan, C.; Fernandez-Busnadiego, R. 10.1101/578427 — cell biology — Posted on 2019-03-15 1794 Rod-shaped tricalbins contribute to PM asymmetry at curved ER-PM contact sites Hoffmann, P. C.; Bharat, T. A. M.; Wozny, M. R.; Miller, E. A.; Kukulski, W. 10.1101/579128 — cell biology — Posted on 2019-03-15 1795 Comparative analysis of novel MGISEQ-2000 sequencing platform vs Illumina HiSeq 2500 for whole-genome sequencing Gorbachev, A.; Kulemin, N.; Naumov, V.; Belova, V.; Kwon, D.; Rebrikova, D.; Korostin, D. 10.1101/577080 — genomics — Posted on 2019-03-15 1796 Sci-Hi-C: a single-cell Hi-C method for mapping 3D genome organization in large number of single cells Ramani, V.; Deng, X.; Qiu, R.; Lee, C.; Disteche, C. M.; Noble, W. S.; Duan, Z.; Shendure, J. 10.1101/579573 — genomics — Posted on 2019-03-15 1797 Kindlin-3 Mutation in Mesenchymal Stem Cells Results in Enhanced Chondrogenesis Kerr, B.; Shi, L.; Jinnah, A.; Willey, J.; Lennon, D.; Caplan, A.; Byzova, T. 10.1101/578690 — cell biology — Posted on 2019-03-15 1798 Analysis of patient derived xenograft studies in Oncology drug development: impact on design and interpretation of future studies Dickinson, J.; de Matas, M.; Dickinson, P.; Mistry, H. 10.1101/579136 — cancer biology — Posted on 2019-03-15 1799 Avoiding potential biases in ses.PD estimations with the Picante software package Molina-Venegas, R. 10.1101/579300 — bioinformatics — Posted on 2019-03-15 1800 Optimization of 3D bioprinting of human neuroblastoma cells using sodium alginate hydrogel Lewicki, J.; Bergman, J.; Kerins, C.; Hermanson, O. 10.1101/579268 — bioengineering — Posted on 2019-03-15 1801 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J. 10.1101/577585 — plant biology — Posted on 2019-03-15 1802 Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens Cross, T.; Ransegnola, B.; Shin, J.-H.; Weaver, A.; Fauntleroy, K.; VanNieuwenhze, M.; Westblade, L.; Dörr, T. 10.1101/578559 — microbiology — Posted on 2019-03-15 1803 Dosing Time Matters Ruben, M. D.; Smith, D. F.; FitzGerald, G. A.; Hogenesch, J. B. 10.1101/570119 — epidemiology — Posted on 2019-03-15 1804 Live detection of neural stem and glioblastoma cells by an oligothiophene derivative Ilkhanizadeh, S.; Gracias, A.; Aslund, A. K.; Back, M.; Simon, R.; Rraklli, V.; Migliori, B.; Kavanagh, E.; Nelander, S.; Westermark, B.; Uhrbom, L.; Forsberg-Nilsson, K.; Teixeira, A. I.; Konradsson, P.; Uhlen, P.; Holmberg, J.; Joseph, B.; Hermanson, O.; Nilsson, P. R. 10.1101/579185 — bioengineering — Posted on 2019-03-15 1805 Multi-grip classification-based prosthesis control with two sensors Krasoulis, A.; Vijayakumar, S.; Nazarpour, K. 10.1101/579367 — bioengineering — Posted on 2019-03-15 1806 Recombinant spider silk protein matrices facilitate multi-analysis of calcium-signaling in neural stem cell-derived AMPA-responsive neurons Lewicka, M.; Rebellato, P.; Lewicki, J.; Uhlen, P.; Rising, A.; Hermanson, O. 10.1101/579292 — bioengineering — Posted on 2019-03-15 1807 Puberty timing and adiposity change across childhood and adolescence: disentangling cause and consequence O'Keeffe, L. M.; Frysz, M.; Bell, J. A.; Howe, L. D.; Fraser, A. 10.1101/578005 — epidemiology — Posted on 2019-03-15 1808 Making Pastoralists Count: Geospatial Methods for the Health Surveillance of Nomadic Populations Wild, H.; Glowacki, L.; Maples, S.; Mejia-Guevara, I.; Krystosik, A.; Bonds, M. H.; Hiruy, A.; LaBeaud, A. D.; Barry, M. 10.1101/572685 — epidemiology — Posted on 2019-03-15 1809 Selection and co-selection of antibiotic resistances among Escherichia coli by antibiotic use in primary care: an ecological analysis Pouwels, K.; Muller-Pebody, B.; Smieszek, T.; Hopkins, S.; Robotham, J. 10.1101/573360 — epidemiology — Posted on 2019-03-15 1810 Physical activity interventions for major chronic disease: a matched-pair analysis of Cochrane and non-Cochrane systematic reviews Hacke, C.; Nunan, D. 10.1101/571901 — epidemiology — Posted on 2019-03-15 1811 A Comparison Of Robust Mendelian Randomization Methods Using Summary Data Slob, E. A. W.; Burgess, S. 10.1101/577940 — epidemiology — Posted on 2019-03-15 1812 Genetic variation in apolipoprotein A-I concentrations and risk of coronary artery disease Karjalainen, M. K.; Holmes, M. V.; Wang, Q.; Anufrieva, O.; Kahonen, M.; Lehtimaki, T.; Havulinna, A. S.; Kristiansson, K.; Salomaa, V.; Perola, M.; Viikari, J. S.; Raitakari, O. T.; Jarvelin, M.-R.; Ala-Korpela, M.; Kettunen, J. 10.1101/576504 — epidemiology — Posted on 2019-03-15 1813 SMAUG: Analyzing single-molecule tracks with nonparametric Bayesian statistics Karslake, J.; Donarski, E. D.; Shelby, S. A.; Demey, L. M.; DiRita, V. J.; Veatch, S. L.; Biteen, J. S. 10.1101/578567 — biophysics — Posted on 2019-03-15 1814 Performance comparison of the Maxim and Sedia Limiting Antigen Avidity assays for incidence surveillance Sempa, J. B.; Welte, A.; Busch, M. P.; Hall, J.; Hampton, D.; Keating, S. M.; Facente, S. N.; Marson, K.; Parkin, N.; Pilcher, C. D.; Murphy, G.; Grebe, E.; The Consortium for the Evaluation and Performance, 10.1101/572677 — epidemiology — Posted on 2019-03-15 1815 Imaging The Electrical Activity Of Organelles In Living Cells Matamala, E.; Castillo, C.; Vivar-Casas, J. P.; Brauchi, S. E. 10.1101/578765 — cell biology — Posted on 2019-03-15 1816 Cell-type specific innervation of cortical pyramidal cells at their apical tufts Karimi, A.; Odenthal, J.; Drawitsch, F.; Boergens, K. M.; Helmstaedter, M. 10.1101/571695 — neuroscience — Posted on 2019-03-15 1817 Circuits that encode and predict alcohol associated preference. Scaplen, K. M.; Talay, M.; Salamon, S.; Nunez, K. M.; Waterman, A. G.; Gang, S.; Song, S. L.; Barnea, G.; Kaun, K. R. 10.1101/578401 — neuroscience — Posted on 2019-03-15 1818 Rere-dependent Retinoic Acid signaling controls brain asymmetry and handedness Rebagliati, M.; Vihais-Neto, G.; Petiet, A.; Lange, M.; Michaut, A.; Plassat, J.-L.; Vermot, J.; Riet, F.; Noblet, V.; Brasse, D.; Laquerriere, P.; Cussigh, D.; Dray, N.; Bedu, S.; Gomaa, M. S.; Simons, C.; Meziane, H.; Lehericy, S.; Bally-Cuif, L.; Pourquie, O. 10.1101/578625 — neuroscience — Posted on 2019-03-15 1819 HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4 Raghawan, A. K.; Ramaswami, R.; Radha, V.; Swarup, G. 10.1101/578138 — cell biology — Posted on 2019-03-15 1820 RBPSponge: genome-wide identification of lncRNAs that sponge RBPs HafezQorani, S.; Houdjedj, A.; Arici, M.; Said, A.; Kazan, H. 10.1101/566828 — bioinformatics — Posted on 2019-03-15 1821 Mechanism of the allosteric activation of the ClpP protease machinery by substrates and active-site inhibitors Felix, J.; Weinhaupl, K.; Chipot, C.; Dehez, F.; Hessel, A.; F. Gauto, D.; Morlot, C.; Abian, O.; Gutsche, I.; Velazquez-Campoy, A.; Schanda, P.; Fraga, H. 10.1101/578260 — biochemistry — Posted on 2019-03-15 1822 Evolution of Phototransduction Genes in Lepidoptera Macias-Munoz, A.; Rangel Olguin, A. G.; Briscoe, A. D. 10.1101/577031 — evolutionary biology — Posted on 2019-03-15 1823 Selection of a Malignant Subpopulation from a Colorectal Cancer Cell Line Lai, P.-L.; Chen, T.-C.; Feng, C.-Y.; Lin, H.; Wu, N.; Chen, Y.; Hsiao, M.; Lu, J.; Huang, H.-C. 10.1101/578823 — cancer biology — Posted on 2019-03-15 1824 Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis Durif, G.; Modolo, L.; Mold, J. E.; Lambert-Lacroix, S.; Picard, F. 10.1101/211938 — bioinformatics — Posted on 2019-03-15 1825 Probing the flavin transfer mechanism in alkanesulfonate monooxygenase system Dayal, P.; Ellis, H. 10.1101/433839 — biochemistry — Posted on 2019-03-15 1826 Enabling large-scale genome editing by reducing DNA nicking Smith, C. J.; Castanon, O.; Said, K.; Volf, V.; Khoshakhlagh, P.; Hornick, A.; Ferreira, R.; Wu, C.-T.; Güell, M.; Garg, S.; Myllykallio, H.; Church, G. M. 10.1101/574020 — synthetic biology — Posted on 2019-03-15 1827 1-Methyl-tryptophan enantiomers differently affect the cross- talking between mononuclear and tumor cells and interferon-γ production. Branquinho, M. S. F.; Silva, M. B. B.; Clara, R. O.; Julio, A. R.; Engler, S. S. M.; Pinto Junior, E.; Campa, A. 10.1101/578369 — pharmacology and toxicology — Posted on 2019-03-15 1828 Dynamics of Mycobacterium tuberculosis Ag85B revealed by sensitive ELISA Ernst, J. D.; Cornelius, A.; Bolz, M. 10.1101/574996 — microbiology — Posted on 2019-03-15 1829 Genome-Wide Polygenic Risk Scores and prediction of Gestational Diabetes in South Asian Women Lamri, A.; Mao, S.; Desai, D.; Gupta, M.; Pare, G.; Anand, S. S. 10.1101/574616 — genomics — Posted on 2019-03-15 1830 Dynamic metabolic profiles of marine macroalga Ulva prolifera during fragmentation-induced proliferation He, Y.; Wang, Y.; Hu, C.; Sun, X.; Li, Y.; Xu, N. 10.1101/578963 — physiology — Posted on 2019-03-15 1831 Cortico-basal white matter alterations occurring in Parkinson’s disease Isaacs, B.; Trutti, A. C.; Pelzer, E.; Tittgemeyer, M.; Temel, Y.; Forstmann, B.; Keuken, M. 10.1101/576991 — neuroscience — Posted on 2019-03-14 1832 MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus Cherfils, J.; Galicia, C.; Lhospice, S.; Fernandez Varela, P.; Trapani, S.; Zhang, W.; Navaza, J.; Mignot, T. 10.1101/577387 — microbiology — Posted on 2019-03-14 1833 Genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep Banos, G.; Clark, E.; Bush, S.; Dutta, P.; Bramis, G.; Arsenos, G.; Hume, D.; Psifidi, A. 10.1101/577015 — genetics — Posted on 2019-03-14 1834 Damped White Noise Diffusion with Memory for Diffusing Microprobes in Ageing Fibrin Gels Aure, R. L.; Bernido, C. C.; Bernido, M. V. C.; Bacabac, R. G. 10.1101/576710 — biophysics — Posted on 2019-03-14 1835 Genomes from Bacteria Associated with the Canine Oral Cavity: a Test Case for Automated Genome-Based Taxonomic Assignment Coil, D. A.; Jospin, G.; Darling, A. E.; Wallis, C.; Davis, I. J.; Harris, S.; Eisen, J. A.; Holcombe, L. J.; O'Flynn, C. 10.1101/577163 — bioinformatics — Posted on 2019-03-14 1836 Hepatoprotective effects of Erythrina abyssinica Lam Ex Dc against Non Alcoholic Fatty Liver Disease in Sprague Dawley Rats MACHARIA, F.; MWANGI, P. W.; Yenesew, A.; Bukachi, F.; NYAGA, N. M.; Wafula, D. K. 10.1101/577007 — pathology — Posted on 2019-03-14 1837 Sickle cell disease complications: prevalence and resource utilization Shah, N.; Bhor, M.; Xie, L.; Paulose, J.; Yuce, H. 10.1101/577189 — epidemiology — Posted on 2019-03-14 1838 Swallowing and chewing difficulties are associated with presynaptic dopaminergic dysfunction and greater non-motor symptom burden in early drug-naïve Parkinson’s patients Polychronis, S.; Dervenoulas, G.; Yousaf, T.; Niccolini, F.; Pagano, G.; Politis, M. 10.1101/577148 — neuroscience — Posted on 2019-03-14 1839 A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast C. neoformans Burke, J. E.; Longhurst, A. D.; Natarajan, P.; Rao, B.; Liu, S. J.; Sales-Lee, J.; Mortensen, Y.; Moresco, J.; Diedrich, J. K.; Yates, J. R.; Madhani, H. D. 10.1101/577924 — molecular biology — Posted on 2019-03-14 1840 Treatment Failure among People living with HIV taking Antiretroviral Therapy in Ethiopia Misganie, Y. G.; G/Egziabhier, A.; Zealiyas, K.; Tilahun, R.; Girma, M.; G/Michael, G.; Deressa, T.; Abate, E.; Assefa, Y. 10.1101/577049 — epidemiology — Posted on 2019-03-14 1841 The transcription factor Odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop Abdusselamoglu, M. D.; Eroglu, E.; Burkard, T. R.; Knoblich, J. 10.1101/576736 — developmental biology — Posted on 2019-03-14 1842 Chemokine signaling links cell cycle progression and cilia formation for left-right symmetry breaking Liu, J.; Zhu, C.; Ning, G.; Yang, L.; Cao, Y.; Huang, S.; Wang, Q. 10.1101/578351 — developmental biology — Posted on 2019-03-14 1843 Multichannel Silicon Probes for Awake Hippocampal Recordings in Large Animals Ulyanova, A. V.; Cottone, C.; Adam, C. D.; Gagnon, K. G.; Cullen, D. K.; Holtzman, T.; Jamieson, B. G.; Koch, P. F.; Chen, H. I.; Johnson, V. E.; Wolf, J. A. 10.1101/400812 — neuroscience — Posted on 2019-03-14 1844 HCF-2 inhibits cell proliferation and activates differentiation-gene expression programs Gudkova, D.; Dergai, O.; Praz, V.; Herr, W. 10.1101/577890 — molecular biology — Posted on 2019-03-14 1845 Monosodium Iodoacetate delays regeneration and inhibits hypertrophy in skeletal muscle cells in vitro Rimington, R. P.; Player, D. J.; Martin, N. R. W.; Lewis, M. P. 10.1101/577866 — cell biology — Posted on 2019-03-14 1846 Parallel high-performance computing algorithm to generate FEM-compliant volumetric mesh representations of biomolecules at atomic scale Lopez, J.; Botello, S.; Herrera, R.; Carrillo-Tripp, M. 10.1101/578658 — biophysics — Posted on 2019-03-14 1847 Maintaining arm control during self-triggered and unpredictable unloading perturbations. Reschechtko, S.; Johannson, A. S.; Pruszynski, J. A. 10.1101/578450 — neuroscience — Posted on 2019-03-14 1848 An open resource of structural variation for medical and population genetics Collins, R. L.; Brand, H.; Karczewski, K. J.; Zhao, X.; Alflödi, J.; Khera, A. V.; Francioli, L. C.; Gauthier, L. D.; Wang, H.; Watts, N. A.; Solomonson, M.; O'Donnell-Luria, A.; Baumann, A.; Munshi, R.; Lowther, C.; Walker, M.; Whelan, C.; Huang, Y.; Brookings, T.; Sharpe, T.; Stone, M. R.; Valkanas, E.; Fu, J.; Tiao, G.; Laricchia, K. M.; Stevens, C.; Gupta, N.; Margolin, L.; The Genome Aggregation Database (gnomAD) Productio, ; The gnomAD Consortium, ; Spertus, J. A.; Taylor, K. D.; Lin, H. J.; Rich, S. S.; Post, W.; Chen, Y.-D. I.; Rotter, J. I.; Nusbaum, C.; Philippakis, A.; Lander, E 10.1101/578674 — genomics — Posted on 2019-03-14 1849 Oncogenic hijacking of a developmental transcription factor evokes therapeutic vulnerability for ROS-induction in Ewing sarcoma Marchetto, A.; Ohmura, S.; Orth, M. F.; Li, J.; Wehweck, F. S.; Knott, M. M. L.; Stein, S.; Saucier, D.; Arrigoni, C.; Gerke, J. S.; Baldauf, M. C.; Musa, J.; Dallmayer, M.; Hoelting, T. L. B.; Moretti, M.; Amatruda, J. F.; Romero-Perez, L.; Cidre-Aranaz, F.; Kirchner, T.; Sannino, G.; Grunewald, T. G. P. 10.1101/578666 — cancer biology — Posted on 2019-03-14 1850 Modeling the stimulatory network in Natural Killer cells Makaryan, S. Z.; Finley, S. D. 10.1101/395756 — systems biology — Posted on 2019-03-14 1851 The multi-peak adaptive landscape of crocodylomorph body size evolution Godoy, P. L.; Benson, R. B. J.; Bronzati, M.; Butler, R. J. 10.1101/405621 — paleontology — Posted on 2019-03-14 1852 The accessibility of human centromeric chromatin is modulated by elastic CENP-A nucleosomes Melters, D. P.; Pitman, M.; Rakshit, T.; Bui, M.; Dimitriadis, E. K.; Papoian, G. A.; Dalal, Y. 10.1101/392787 — biochemistry — Posted on 2019-03-14 1853 Profiling the genome-wide landscape of tandem repeat expansions Mousavi, N.; Shleizer-Burko, S.; Yanicky, R.; Gymrek, M. 10.1101/361162 — genomics — Posted on 2019-03-14 1854 Translating GWAS-identified loci for cardiac rhythm and rate using an in vivo image- and CRISPR-Cas9-based approach von der Heyde, B.; Emmanouilidou, A.; Klingström, T.; Mazzaferro, E.; Vicenzi, S.; Jumaa, S.; Dethlefsen, O.; Snieder, H.; de Geus, E.; Ingelsson, E.; Allalou, A.; Brooke, H. L.; den Hoed, M. 10.1101/385500 — genomics — Posted on 2019-03-14 1855 Sex makes them sleepy: change in host reproductive status induces diapause in a parasitoid population experiencing harsh winters Tougeron, K.; Brodeur, J.; van Baaren, J.; Renault, D.; Le Lann, C. 10.1101/371385 — ecology — Posted on 2019-03-14 1856 The \"sewing machine\" for minimally invasive neural recording Hanson, T. L.; Diaz-Botia, C. A.; Kharazia, V.; Maharbiz, M. M.; Sabes, P. N. 10.1101/578542 — neuroscience — Posted on 2019-03-14 1857 Constitutive Siglec-1 expression by human dendritic cell precursors enables HIV-1 replication and transmission RUFFIN, N.; Gea-Mallorqui, E.; Brouiller, F.; Jouve, M.; Silvin, A.; See, P.; Dutertre, C.-A.; Ginhoux, F.; Benaroch, P. 10.1101/578377 — immunology — Posted on 2019-03-14 1858 Changes in gene expression shift and switch genetic interactions Li, X.; Lalic, J.; Baeza-Centurion, P.; Dhar, R.; Lehner, B. 10.1101/578419 — genetics — Posted on 2019-03-14 1859 Liver X Receptor β Controls Hepatic Stellate Cell Activation via Hedgehog Signaling Zhong, L.; Ning, B.; Du, X.; Shengjie, H.; Cai, C.; Zhou, Y.; Deng, L.; Shen, W. 10.1101/577833 — cell biology — Posted on 2019-03-14 1860 Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens Cross, T.; Ransegnola, B.; Shin, J.-H.; Weaver, A.; Fauntleroy, K.; VanNieuwenhze, M.; Westblade, L.; Dörr, T. 10.1101/578559 — microbiology — Posted on 2019-03-14 1861 Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells Hsu, A.; Liu, S.; Brasseale, K.; Syahirah, R.; Wan, J.; Deng, Q. 10.1101/578583 — immunology — Posted on 2019-03-14 1862 Fog signaling has diverse roles in epithelial morphogenesis in insects Frey, N.; Benton, M. A.; Nunes da Fonseca, R.; von Levetzow, C.; Stappert, D.; Hakeemi, M. S.; Conrads, K.; Pechmann, M.; Panfilio, K. A.; Lynch, J. A.; Roth, S. 10.1101/578526 — developmental biology — Posted on 2019-03-14 1863 SMAUG: Analyzing single-molecule tracks with nonparametric Bayesian statistics Karslake, J.; Donarski, E. D.; Shelby, S. A.; Demey, L. M.; DiRita, V. J.; Veatch, S. L.; Biteen, J. S. 10.1101/578567 — biophysics — Posted on 2019-03-14 1864 Uncovering mechanisms of global ocean change effects on the Dungeness crab (Cancer magister) through metabolomics analysis Trigg, S. A.; McElhany, P.; Maher, M.; Perez, D.; Busch, D. S.; Nichols, K. M. 10.1101/574798 — systems biology — Posted on 2019-03-14 1865 Biological age is a universal marker of aging, stress, and frailty Pyrkov, T. V.; Fedichev, P. O. 10.1101/578245 — systems biology — Posted on 2019-03-14 1866 Specific type 1 diabetes risk genes underpin age-at-diagnosis and indicate joint defects in immunity, beta-cell fragility and responses to viral infections in early-onset disease. Inshaw, J.; Cutler, A. J.; Crouch, D. J.; Wicker, L. S.; Todd, J. A. 10.1101/577304 — genetics — Posted on 2019-03-14 1867 A beneficial genomic rearrangement creates multiple versions of calcipressin in C. elegans Zhao, Y.; Wan, J.; Biliya, S.; Brady, S.; Lee, D.; Andersen, E.; Vannberg, F.; Lu, H.; McGrath, P. 10.1101/578088 — evolutionary biology — Posted on 2019-03-14 1868 HDAC6 promotes PMA-induced megakaryocyte differentiation of K562 cells by regulating ROS levels via NOX4 and repressing Glycophorin A Kummari, G.; Gutti, R. K.; Kalle, A. M. 10.1101/578096 — developmental biology — Posted on 2019-03-14 1869 Dysregulated wild-type cell division at the interface between host and oncogenic epithelium Moruzzi, M.; Nestor-Bergmann, A.; Brennan, K.; Woolner, S. 10.1101/578146 — cell biology — Posted on 2019-03-14 1870 Differential effects of two HDAC inhibitors with distinct concomitant DNA hypermethylation or hypomethylation in breast cancer cells Kalle, A. M.; Wang, Z. 10.1101/578062 — cancer biology — Posted on 2019-03-14 1871 The Antagonism of Folate Receptor by the Integrase Inhibitor Dolutegravir Cabrera, R. M.; Souder, J. P.; Steele, J. W.; Yeo, L.; Tukeman, G.; Gorelick, D. A.; Finnell, R. H. 10.1101/576272 — pharmacology and toxicology — Posted on 2019-03-14 1872 Cell type-specific monoclonal antibody cross-reactivity screening in non-human primates and development of comparative immunophenotyping panels for CyTOF Bjornson-Hooper, Z. B.; Fragiadakis, G. K.; Spitzer, M. H.; Madhireddy, D.; Hu, K.; Lundsten, K.; Nolan, G. P. 10.1101/577759 — immunology — Posted on 2019-03-14 1873 Quantifying and understanding well-to-well contamination in microbiome research Minich, J. J.; Sanders, J.; Amir, A.; Humphrey, G.; Gilbert, J. A.; Knight, R. 10.1101/577718 — genomics — Posted on 2019-03-14 1874 Computational comparison of developmental cell lineage trees by alignments Yuan, M.; Yang, X.; Lin, J.; Cao, X.; Chen, F.; Zhang, X.; Li, Z.; Zheng, G.; Wang, X.; Chen, X.; Yang, J.-R. 10.1101/577809 — bioinformatics — Posted on 2019-03-14 1875 A rapid method to determine the bactericidal activity of compounds against non-replicating Mycobacterium tuberculosis at low pH Early, J.; Mullen, S.; Parish, T. 10.1101/578195 — microbiology — Posted on 2019-03-14 1876 Comparative Analysis of Electrostatic Models for Ligand Docking Sartori, G. R.; Nascimento, A. S. 10.1101/577643 — biophysics — Posted on 2019-03-14 1877 Scalable methods for analyzing and visualizing phylogenetic placement of metagenomic samples Czech, L.; Stamatakis, A. 10.1101/346353 — bioinformatics — Posted on 2019-03-14 1878 Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects Klicznik, M. M.; Morawski, P. A.; Höllbacher, B.; Varkhande, S.; Motley, S.; Kuri-Cervantes, L.; Goodwin, E.; Rosenblum, M. D.; Long, S. A.; Brachtl, G.; Duhen, T.; Betts, M.; Campbell, D.; Gratz, I. K. 10.1101/361758 — immunology — Posted on 2019-03-14 1879 Soil salinity inhibits plant shade avoidance Hayes, S.; Pantazopoulou, C. K.; van Gelderen, K.; Reinen, E.; Tween, A.; Sharma, A.; de Vries, M.; Prat, S.; Schuurink, R.; Testerink, C.; Pierik, R. 10.1101/289124 — plant biology — Posted on 2019-03-14 1880 Non-coding AUG circRNAs constitute an abundant and conserved subclass of circles Stagsted, L. V. W.; Nielsen, K. M.; Daugaard, I.; Hansen, T. B. 10.1101/328104 — molecular biology — Posted on 2019-03-14 1881 Toxicokinetics of citreoviridin in vivo and in vitro. Uchiyama, Y.; Takino, M.; Noguchi, M.; Shiratori, N.; Sugita-Konishi, Y. 10.1101/578302 — pharmacology and toxicology — Posted on 2019-03-14 1882 Ultra-widefield fluorescein angiography findings in patients with multiple retinal holes. Baek, J.; Jung, B.; Kwon, H.; Jeon, S. 10.1101/578328 — neuroscience — Posted on 2019-03-14 1883 NET-prism enables RNA polymerase-dedicated transcriptional interrogation at nucleotide resolution Mylonas, C.; Tessarz, P. 10.1101/246827 — genomics — Posted on 2019-03-14 1884 Relationship between ocean area and incidence of anthropogenic debris ingested by longnose lancetfish (Alepisaurus ferox) UCHIDA, K.; Kuroda, M.; Miyamoto, Y.; Hagita, R.; Shiode, D.; Joshima, H.; Nemoto, M.; Hamada, H.; Yamada, Y.; Takada, H.; Yamashita, R.; Fukunaga, K. 10.1101/578310 — ecology — Posted on 2019-03-14 1885 Short-term effects of hurricanes Maria and Irma on forest birds of Puerto Rico Lloyd, J. D.; Rimmer, C. C.; Salguero Faria, J. 10.1101/578336 — ecology — Posted on 2019-03-14 1886 Short-time fractal analysis of biological autoluminescence Dlask, M.; Kukal, J.; Sovka, P.; Poplova, M.; Cifra, M. 10.1101/578286 — biophysics — Posted on 2019-03-14 1887 CHOP: Haplotype-aware path indexing in population graphs Mokveld, T. O.; Linthorst, J.; Al-Ars, Z.; Holstege, H.; Reinders, M. 10.1101/305268 — bioinformatics — Posted on 2019-03-14 1888 Automated 3D Axonal Morphometry of White Matter Abdollahzadeh, A.; Belevich, I.; Jokitalo, E.; Tohka, J.; Sierra, A. 10.1101/239228 — neuroscience — Posted on 2019-03-14 1889 Drought Affects the Antioxidant System and Stomatal Aperture in Zanthoxylum bungeanum Maxim. Fei, X.; Hu, H.; Li, J.; Liu, Y.; Wei, A. 10.1101/578294 — cell biology — Posted on 2019-03-14 1890 A decade of empirical research on research integrity: what have we (not) looked at? Aubert Bonn, N.; Pinxten, W. 10.1101/567263 — scientific communication and education — Posted on 2019-03-14 1891 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1 Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P.; Matos, J.; Geymonat, M.; Carballo, J. A. 10.1101/571083 — genetics — Posted on 2019-03-14 1892 The Endocrine and Metabolic Response in Male Survivors of Major Trauma Foster, M. A.; Taylor, A. E.; Hill, N. E.; Bentley, C.; Bishop, J.; Bion, J. F.; Fallowfield, J. L.; Woods, D. R.; Bancos, I.; Midwinter, M.; Lord, J.; Arlt, W. 10.1101/577502 — physiology — Posted on 2019-03-14 1893 Soft tissue calcification in mice is governed by fetuin-A, pyrophosphate and magnesium Babler, A.; Schmitz, C.; Buescher, A.; Herrmann, M.; Gremse, F.; Gorgels, T. G.; Floege, J.; Jahnen-Dechent, W. 10.1101/577239 — physiology — Posted on 2019-03-14 1894 Rapid invariant encoding of scene layout in human OPA Henriksson, L.; Mur, M.; Kriegeskorte, N. 10.1101/577064 — neuroscience — Posted on 2019-03-14 1895 Identifying the most influential features of neural population responses for information encoding and behavior Nogueira, R.; Peltier, N. E.; Anzai, A.; DeAngelis, G. C.; Martinez-Trujillo, J.; Moreno-Bote, R. 10.1101/577379 — neuroscience — Posted on 2019-03-14 1896 Expression of ppsD, a gene involved in synthesis of Mycobacterium tuberculosis virulence factor PDIM, reflects treatment response in pulmonary tuberculosis patients Sriraman, K.; Kekane, R.; Shah, D.; Saranath, D.; Mistry, N. 10.1101/576470 — microbiology — Posted on 2019-03-14 1897 Stress-Induced Transcriptional Memory Accelerates Promoter-Proximal Pause-Release and Decelerates Termination over Mitotic Divisions Vihervaara, A.; Mahat, D. B.; Himanen, S. V.; Blom, M. A. H.; Lis, J. T.; Sistonen, L. 10.1101/576959 — molecular biology — Posted on 2019-03-14 1898 OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances reprogramming to epithelial lineages Watanabe, K.; Liu, Y.; Noguchi, S.; Murray, M.; Chang, J.-C.; Kishima, M.; Nishimura, H.; Hashimoto, K.; Minoda, A.; Suzuki, H. 10.1101/577692 — cell biology — Posted on 2019-03-14 1899 The model of local axon homeostasis - explaining the role and regulation of microtubule bundles in axon maintenance and pathology Hahn, I.; Voelzmann, A.; Liew, Y.-T.; Costa-Gomes, B.; Prokop, A. 10.1101/577320 — cell biology — Posted on 2019-03-14 1900 3D rotational motion of an endocytic vesicle on a complex microtubule network in a living cell Higuchi, H.; Lee, S. 10.1101/576702 — biophysics — Posted on 2019-03-14 1901 Structural basis of internal peptide recognition by PDZ domains using molecular dynamics simulations Sain, N.; Mohanty, D. 10.1101/575233 — bioinformatics — Posted on 2019-03-14 1902 Pathogen genetic control of transcriptome variation in the Arabidopsis thaliana - Botrytis cinerea pathosystem Soltis, N. E.; Zhang, W.; Corwin, J. A.; Atwell, S.; Kliebenstein, D. J. 10.1101/577585 — plant biology — Posted on 2019-03-14 1903 Spatially modulated alpha-band activity does not mediate tactile remapping and fast overt orienting behavior Ossandon, J. P.; König, P.; Heed, T. 10.1101/576850 — neuroscience — Posted on 2019-03-14 1904 Nonlinear mixed selectivity supports reliable neural computation Johnston, W. J.; Palmer, S. E.; Freedman, D. J. 10.1101/577288 — neuroscience — Posted on 2019-03-14 1905 Ten-year retrospective analysis of Acinetobacter baumannii clinical isolates reveals a proportionately large, non-nosocomial, multidrug-resistant endemic reservoir Calix, J. J.; Burnham, J. P.; Feldman, M. F. 10.1101/576868 — microbiology — Posted on 2019-03-14 1906 Land-use and related pressures have reduced biotic integrity more on islands than on mainlands Sanchez Ortiz, K.; Gonzalez, R.; De Palma, A.; Newbold, T.; Hill, S.; Tylianakis, J.; Borger, L.; Lysenko, I.; Purvis, A. 10.1101/576546 — ecology — Posted on 2019-03-14 1907 Planar cell polarity in the C. elegans embryo emerges by differential retention of aPARs at cell-cell contacts Dutta, P.; Odedra, D.; Pohl, C. 10.1101/576777 — cell biology — Posted on 2019-03-14 1908 Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography Weinert, T.; Skopintsev, P.; James, D.; Dworkowski, F.; Panepucci, E.; Kekilli, D.; Furrer, A.; Brünle, S.; Mous, S.; Ozerov, D.; Nogly, P.; Wang, M.; Standfuss, J. 10.1101/576629 — biophysics — Posted on 2019-03-14 1909 Transcriptomic analysis of the BDNF-induced JAK/STAT pathway in neurons: a window into epilepsy-associated gene expression Hixson, K. M.; Cogswell, M. C.; Brooks-Kayal, A. R.; Russek, S. J. 10.1101/577627 — neuroscience — Posted on 2019-03-14 1910 Dynamic changes in innate immune and T cell function and composition at the nasal mucosa across the human lifespan Reine, J.; Carniel, B. F.; Solorzano, C.; Mitsi, E.; Pojar, S.; Nikolau, E.; German, E. L.; Hyder-Wright, A. D.; Hill, H.; Hales, C.; Brown, L.; Horsley, V.; Hughes, L.; Zaidi, S.; Connor, V.; Morton, B.; Collins, A. M.; Rylance, J.; Adler, H.; McNamara, P. S.; Ferreira, D. M.; Jochems, S. P. 10.1101/576744 — immunology — Posted on 2019-03-14 1911 Optimal strategies for pirate phage spreading Mitarai, N. 10.1101/576587 — ecology — Posted on 2019-03-14 1912 Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc Lee, Y.; Wiriyasermkul, P.; Jin, C.; Quan, L.; Ohgaki, R.; Okuda, S.; Kusakizako, T.; Nishizawa, T.; Oda, K.; Ishitani, R.; Yokoyama, T.; Nakane, T.; Shirouzu, M.; Endou, H.; Nagamori, S.; Kanai, Y.; Nureki, O. 10.1101/577551 — biochemistry — Posted on 2019-03-14 1913 Facilitation and inhibition of firing activity and N-methyl-D-aspartate-evoked responses of CA1 hippocampal pyramidal cells by alpha7 nicotinic acetylcholine receptor selective compounds in vivo Bali, Z. K.; Nagy, L. V.; Budai, D.; Hernadi, I. 10.1101/576520 — neuroscience — Posted on 2019-03-14 1914 Dynamic network properties of the interictal brain determine whether seizures appear focal or generalised Woldman, W.; Schmidt, H.; Abela, E.; Chowdhury, F. A.; Pawley, A. D.; Jewell, S.; Richardson, M. P.; Terry, J. R. 10.1101/576785 — neuroscience — Posted on 2019-03-14 1915 Ibuprofen-mediated potential inhibition of biofilm development and quorum sensing in Pseudomonas aeruginosa Dai, L.; Wu, T.-q.; Wang, Z.-h.; Yuan, R.; Ding, Y.; Zhang, W.-c.; Chu, S. p.; Ju, S.; Yu, J. 10.1101/576447 — microbiology — Posted on 2019-03-14 1916 Iron-sulfur cluster repair contributes to Y. pseudotuberculosis survival within deep tissues Davis, K. M.; Krupp, J.; Clark, S.; Isberg, R. R. 10.1101/576454 — microbiology — Posted on 2019-03-14 1917 CTCF and Cohesin link sex-biased distal regulatory elements to sex-biased gene expression in mouse liver Matthews, B. J.; Waxman, D. J. 10.1101/577577 — genomics — Posted on 2019-03-14 1918 Natural allelic variations of Saccharomyces cerevisiae impact stuck fermentation due to the combined effect of ethanol and temperature; a QTL-mapping study. Marullo, P.; Durrens, P.; Peltier, E.; Bernard, M.; Mansour, C.; Dubourdieu, D. 10.1101/576835 — genetics — Posted on 2019-03-14 1919 Low marine food levels mitigate high migration costs in anadromous populations Chaparro-Pedraza, P. C.; De Roos, A. 10.1101/577353 — ecology — Posted on 2019-03-14 1920 Abrogating ALIX interactions results in stuttering of the ESCRT machinery Gupta, S.; Bendjennat, M.; Saffarian, S. 10.1101/576926 — cell biology — Posted on 2019-03-14 1921 Luminal Calcification of the Microvasculature in Fetuin-A Deficient Mice Leads to Premature Aging and Death Herrmann, M.; Babler, A.; Moshkova, I.; Gremse, F.; Kiessling, F.; Kusebauch, U.; Nelea, V.; Kramann, R.; Moritz, R. L.; McKee, M. D.; Jahnen-Dechent, W. 10.1101/577098 — physiology — Posted on 2019-03-14 1922 Age-related alterations in functional connectivity along the longitudinal axis of the hippocampus and its subfields Stark, S. M.; Frithsen, A.; Stark, C. E. 10.1101/577361 — neuroscience — Posted on 2019-03-14 1923 Direct proteolytic control of an extracytoplasmic function RNA polymerase sigma factor Bilyk, B.; Kim, S.; BAKER, T.; Seipke, R. F. 10.1101/576462 — microbiology — Posted on 2019-03-14 1924 Discovery of small alarmone synthetases and their inhibitors as toxin-antitoxin loci Jimmy, S.; Saha, C. K.; Stavropoulos, C. G.; Garcia-Pino, A.; Hauryliuk, V.; Atkinson, G. C. 10.1101/575399 — microbiology — Posted on 2019-03-14 1925 Epistasis detection and modeling for genomic selection in cowpea (Vigna unguiculata. L. Walp.) Olatoye, M. O.; Hu, Z.; Aikpokpodion, P. O. 10.1101/576819 — genetics — Posted on 2019-03-14 1926 Population histories of the United States revealed through fine-scale migration and haplotype analysis Dai, C. L.; Vazifeh, M. M.; Yeang, C.-H.; Tachet, R.; Vilar, M. G.; Daly, M. J.; Ratti, C.; Martin, A. R. 10.1101/577411 — genetics — Posted on 2019-03-14 1927 Common variants in OSMR contribute to carotid plaque vulnerability van Keulen, D.; van Koeverden, I. D.; Boltjes, A.; Princen, H. M. G.; van Gool, A. J.; de Borst, G. J.; Asselbergs, F. W.; Tempel, D.; Pasterkamp, G.; van der Laan, S. W. 10.1101/576793 — genetics — Posted on 2019-03-14 1928 Prenatal diagnosis of HNF1B-associated renal cysts: Need to differentiate intragenic variants from 17q12 microdeletion syndrome? Vasileiou, G.; Hoyer, J.; Thiel, C. T.; Schaefer, J.; Zapke, M. Z.; Krumbiegel, M.; Kraus, C.; Zweier, M.; Uebe, S.; Ekici, A. B.; Schneider, M.; Wiesener, M.; Rauch, A.; Faschingbauer, F.; Reis, A.; Zweier, C.; Popp, B. 10.1101/576918 — genetics — Posted on 2019-03-14 1929 Molecular biogeography and host relations of a parasitoid fly Gray, D. A.; Kunerth, H. D.; Zuk, M.; Cade, W. H.; Balenger, S. L. 10.1101/576892 — evolutionary biology — Posted on 2019-03-14 1930 Botswana’s wildlife losing ground as Kalahari Wildlife Management Areas (WMAs) are dezoned for livestock expansion Keeping, D.; Kashe, N.; Langwane, H.; Sebati, P.; Molese, N.; Gielen, M.-C.; Keitsile-Barungwi, A.; Khukwe, Q.; Brahman, !Nate 10.1101/576496 — ecology — Posted on 2019-03-14 1931 A role for liquid-liquid phase separation in ESCRT-mediated nuclear envelope reformation. von Appen, A.; Lajoie, D.; Johnson, I. E.; Trnka, M.; Pick, S. M.; Burlingame, A. L.; Ullman, K. S.; Frost, A. 10.1101/577460 — cell biology — Posted on 2019-03-14 1932 A HaloTag-TEV genetic cassette for mechanical phenotyping of native proteins Rivas-Pardo, J. A.; Li, Y.; Martonfalvi, Z.; Tapia-Rojo, R.; Unger, A.; Fernandez-Trasancos, A.; Herrero-Galan, E.; Velazquez-Carreras, D.; Linke, W. A.; Fernandez, J. M.; Alegre-Cebollada, J. 10.1101/577445 — biophysics — Posted on 2019-03-14 1933 Supramodal sentence processing in the human brain: fMRI evidence for the influence of syntactic complexity in more than 200 participants Udden, J.; Hulten, A.; Schoffelen, J. M.; Lam, N.; Harbusch, K.; van den Bosch, A.; Kempen, G.; Petersson, K. M.; Hagoort, P. 10.1101/576769 — neuroscience — Posted on 2019-03-14 1934 Vestibular modulation of multisensory integration during actual and vicarious tactile stimulation Ponzo, S.; Kirsch, L. P.; Fotopoulou, A.; Jenkinson, P. M. 10.1101/576611 — neuroscience — Posted on 2019-03-14 1935 Characterization of coral-associated microbial aggregates (CAMAs) within tissues of the coral Acropora hyacinthus Wada, N.; Ishimochi, M.; Matsui, T.; Pollock, F. J.; Tang, S.-L.; Ainsworth, T. D.; Willis, B. L.; Mano, N.; Bourne, D. G. 10.1101/576488 — microbiology — Posted on 2019-03-14 1936 Sex-biased genetic programs in liver metabolism and liver fibrosis are controlled by EZH1 and EZH2 Lau-Corona, D.; Bae, W. K.; Hennighausen, L.; Waxman, D. J. 10.1101/577056 — genomics — Posted on 2019-03-14 1937 Normalization and variance stabilization of single-cell RNA-seq data using regularized negative binomial regression Hafemeister, C.; Satija, R. 10.1101/576827 — genomics — Posted on 2019-03-14 1938 Germ Granules Functions are Memorized by Transgenerationally Inherited Small RNAs Lev, I.; Toker, I. A.; Mor, Y.; Nitzan, A.; Weintraub, G.; Bhonkar, O.; Ben Shushan, I.; Seroussi, U.; Claycomb, J.; Gingold, H.; Zaidel-Bar, R.; Rechavi, O. 10.1101/576934 — genetics — Posted on 2019-03-14 1939 Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish Grzegorski, S. J.; Hu, Z.; Liu, Y.; Yu, X.; Ferguson, A. C.; Madarati, H.; Friedmann, A. P.; Reyon, D.; Kim, P. Y.; Kretz, C. A.; Joung, J. K.; Shavit, J. A. 10.1101/576140 — genetics — Posted on 2019-03-14 1940 Species specificity and intraspecific variation in the chemical profiles of Heliconius butterflies across a large geographic range Darragh, K.; Montejo-Kovacevich, G.; Kozak, K. M.; Morrison, C. R.; Figueiredo, C. M. E.; Ready, J. S.; Salazar, C.; Linares, M.; Byers, K. J. R. P.; Merrill, R. M.; McMillan, W. O.; Schulz, S.; Jiggins, C. D. 10.1101/573469 — evolutionary biology — Posted on 2019-03-14 1941 Sex-specific population dynamics and demography of capercaillie (Tetrao urogallus L.) in a patchy environment Augustine, B.; Kery, M.; Olano Marin, J.; Mollet, P.; Pasinelli, G.; Sutherland, C. 10.1101/576876 — ecology — Posted on 2019-03-14 1942 A core microbiota of the plant-earthworm interaction conserved across soils Jacquiod, S.; Puga-Freitas, R.; Spor, A.; Mounier, A.; Monard, C.; Mougel, C.; Philippot, L.; Blouin, M. 10.1101/571240 — ecology — Posted on 2019-03-14 1943 DNA barcode reference libraries for the monitoring of aquatic biota in Europe: Gap-analysis and recommendations for future work Weigand, H.; Beermann, A. J.; Ciampor, F.; Costa, F. O.; Csabai, Z.; Duarte, S.; Geiger, M. F.; Grabowski, M.; Rimet, F.; Rulik, B.; Strand, M.; Szucsich, N.; Weigand, A. M.; Willassen, E.; Wyler, S. A.; Bouchez, A.; Borja, A.; Ciamporova-Zat'ovicova, Z.; Ferreira, S.; Dijkstra, K.; Eisendle, U.; Freyhof, J.; Gadawski, P.; Graf, W.; Haegerbaeumer, A.; van der Hoorn, B. B.; Japoshvili, B.; Keresztes, L.; Keskin, E.; Leese, F.; Macher, J.; Mamos, T.; Paz, G.; Pesic, V.; Pfannkuchen, D. M.; Pfannkuchen, M. A.; Price, B. W.; Rinkevich, B.; Teixeira, M. A. L.; Varbiro, G.; Ekrem, T. 10.1101/576553 — ecology — Posted on 2019-03-14 1944 Environmental change effects on life history traits and population dynamics of anadromous fishes Chaparro-Pedraza, P. C.; De Roos, A. 10.1101/577262 — ecology — Posted on 2019-03-14 1945 pHluo_M153R-CD63, a bright, versatile live cell reporter of exosome secretion and uptake, reveals pathfinding behavior of migrating cells Sung, B. H.; Pelletier, R. J.; Weaver, A. M. 10.1101/577346 — cell biology — Posted on 2019-03-14 1946 An immunoevasive strategy through clinically-relevant pan cancer genomic and transcriptomic alterations of JAK-STAT signaling components Chang, W. H.; Lai, A. G. 10.1101/576645 — cancer biology — Posted on 2019-03-14 1947 TANGO1 regulates membrane tension to mediate procollagen export Raote, I.; Garcia-Parajo, M. F.; Malhotra, V.; Campelo, F. 10.1101/576637 — biophysics — Posted on 2019-03-14 1948 An open-source and low-cost feeding system for zebrafish facilities Tangara, A.; Paresys, G.; Bouallague, F.; Cabirou, Y.; Fodor, J.; Llobet, V.; Sumbre, G. 10.1101/558205 — neuroscience — Posted on 2019-03-14 1949 A smart polymer for sequence-selective binding, pulldown and release of DNA targets Krieg, E.; Gupta, K.; Dahl, A.; Lesche, M.; Boye, S.; Lederer, A.; Shih, W. M. 10.1101/573030 — molecular biology — Posted on 2019-03-14 1950 First hybrid complete genome of Aeromonas veronii reveals chromosome-mediated novel structural variant mcr-3.19 from human clinical specimen Devanga Ragupathi, N. K.; Muthuirulandi Sethuvel, D. P.; Anandan, S.; Murugan, D.; Asokan, K.; Neethi Mohan, R. G.; Vasudevan, K.; D, T. K.; C, G. P. D.; Veeraraghavan, B. 10.1101/576421 — microbiology — Posted on 2019-03-14 1951 The obese liver environment mediates conversion of NK cells to a less cytotoxic ILC1-like phenotype Cuff, A. O.; Sillito, F.; Dertschnig, S.; Hall, A.; Luong, T.; Chakraverty, R.; Male, V. 10.1101/576538 — immunology — Posted on 2019-03-14 1952 Antibody-mediated cross-linking of gut bacteria hinders the spread of antibiotic resistance Bansept, F.; Marrec, L.; Bitbol, A.-F.; Loverdo, C. 10.1101/577510 — evolutionary biology — Posted on 2019-03-14 1953 Pax9 is required for cardiovascular development and interacts with Tbx1 in the pharyngeal endoderm to control 4th pharyngeal arch artery morphogenesis. Phillips, H. M.; Stothard, C. A.; Shaikh Qureshi, W. M.; Kousa, A. I.; Briones-Leon, A.; Khasawneh, R.; Sanders, R.; Mazotta, S.; Dodds, R.; Seidel, K.; Bates, T.; Nakatomi, M.; Cockell, S.; Schneider, J. E.; Mohun, T. J.; Maehr, R.; Kist, R.; Peters, H.; Bamforth, S. D. 10.1101/576660 — developmental biology — Posted on 2019-03-14 1954 Plasma Circular RNA Panel to Diagnose Hepatitis B Virus-Related Hepatocellular Carcinoma Zhou, W.-p.; Yu, J.; Wang, M.-c.; Ding, W.-b.; Guo, X.-g.; Xu, J.; Xu, Q.-g.; Yang, Y.; Sun, S.-h.; Liu, J.; Qin, L.-x.; Liu, H.; Yang, F. 10.1101/576751 — cancer biology — Posted on 2019-03-14 1955 The sequence of the extruded non-template strand determines the architecture of R-loops. Carrasco-Salas, Y.; Malapert, A.; Sulthana, S.; Molcrette, B.; Chazot-Franguiadakis, L.; Bernard, P.; Chedin, F.; Faivre-Moskalenko, C.; Vanoosthuyse, V. 10.1101/576561 — biophysics — Posted on 2019-03-14 1956 MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labor Paquette, A. G.; Shynlova, O.; Wu, X.; Kibschull, M.; Wang, K.; Price, N. D.; Lye, S. 10.1101/575944 — systems biology — Posted on 2019-03-14 1957 Evaluating artesunate-amodiaquine deployment, efficacy and safety: an in silico pharmacological model Hong, K. B.; Hastings, I.; Kay, K.; Hodel, E. M. 10.1101/567008 — pharmacology and toxicology — Posted on 2019-03-14 1958 White Matter Hyperintensity Quantification in Large-Scale Clinical Acute Ischemic Stroke Cohorts - The MRI-GENIE Study Schirmer, M. D.; Dalca, A. V.; Sridharan, R.; Giese, A.-K.; Donahue, K. L.; Nardin, M. J.; Mocking, S. J. T.; McIntosh, E. C.; Frid, P.; Wasselius, J.; Cole, J. W.; Holmegaard, L.; Jern, C.; Jimenez-Conde, J.; Lemmens, R.; Lindgren, A. G.; Meschia, J. F.; Roquer, J.; Rundek, T.; Sacco, R. L.; Schmidt, R.; Sharma, P.; Slowik, A.; Thijs, V.; Woo, D.; Vagal, A.; Xu, H.; Kittner, S. J.; McArdle, P. F.; Mitchell, B. D.; Rosand, J.; Worrall, B. B.; Wu, O.; Golland, P.; Rost, N. S. 10.1101/552844 — neuroscience — Posted on 2019-03-13 1959 Short-term depression and long-term plasticity together tune sensitive range of synaptic plasticity Deperrois, N.; Graupner, M. 10.1101/565291 — neuroscience — Posted on 2019-03-13 1960 A gravity-based three-dimensional compass in the mouse brain Angelaki, D. E.; Ng, J.; Abrego, A. M.; Cham, H. X.; Dickman, D.; Laurens, J. 10.1101/570382 — neuroscience — Posted on 2019-03-13 1961 Temporal dynamics of inhalation-linked activity across defined subpopulations of mouse olfactory bulb neurons imaged in vivo. Short, S. M.; Wachowiak, M. 10.1101/558999 — neuroscience — Posted on 2019-03-13 1962 Domain-specific working memory, but not dopamine-related genetic variability, shapes reward-based motor learning Holland, P.; Codol, O.; Oxley, E.; Taylor, M.; Hamshere, E.; Joseph, S.; Huffer, L.; Galea, J. M. 10.1101/524900 — neuroscience — Posted on 2019-03-13 1963 Brain meta-state transitions demarcate spontaneous thoughts in movie-viewing and resting cognition Tseng, J.; Poppenk, J. 10.1101/576298 — neuroscience — Posted on 2019-03-14 1964 Mapping Histone Modifications in Low Cell Number and Single Cells Using Antibody-guided Chromatin Tagmentation (ACT-seq) Carter, B.; Ku, W. L.; Tang, Q.; Kang, J. Y.; Zhao, K. 10.1101/571208 — genomics — Posted on 2019-03-13 1965 A Bayesian Approach for Inferring the Impact of a Discrete Character on Rates of Continuous-Character Evolution in the Presence of Background Rate Variation May, M. R.; Moore, B. R. 10.1101/576207 — evolutionary biology — Posted on 2019-03-13 1966 Effective concentrations enforced by intrinsically disordered linkers are governed by polymer physics Sorensen, C. S.; Kjaergaard, M. 10.1101/577536 — biophysics — Posted on 2019-03-14 1967 Metabolic network reductions Tefagh, M.; Boyd, S. P. 10.1101/499251 — systems biology — Posted on 2019-03-13 1968 Effect of topical soluble epoxide hydrolase inhibition in a preclinical diabetic wound healing model. Reisdorf, W.; Rajpal, N.; Gehman, A.; Jain, P.; Burgert, M.; Sonti, S.; Agarwal, P.; Rajpal, D. 10.1101/571984 — physiology — Posted on 2019-03-13 1969 Renal Localization of Plasmodium vivax and Zoonotic Monkey Parasite Plasmodium Knowlesi in Malaria Associated Acute Kidney Injury Acharya, P.; Pramanik, A.; Kaur, C.; Sinha, K.; Dinda, A.; Sankar, J.; Bagga, A.; Agarwal, S.; Sinha, A.; Singh, G. 10.1101/544726 — microbiology — Posted on 2019-03-13 1970 Structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma Lopez, G.; Conkrite, K. L.; Doepner, M.; Rathi, K. S.; Modi, A.; Vaksman, Z.; Farra, L. M.; Hyson, E.; Noureddine, M.; Wei, J. S.; Smith, M. A.; Asgharzadeh, S.; Seeger, R. C.; Khan, J.; Guidry Auvil, J. M.; Gerhard, D. S.; Maris, J. M.; Diskin, S. J. 10.1101/572248 — cancer biology — Posted on 2019-03-13 1971 A distributed lattice of aligned atoms exists in a protein structure: A hierarchical clustering study of displacement parameters in bovine trypsin Ahlberg Gagner, V.; Lundholm, I.; Garcia-Bonete, M.-J.; Rodilla, H.; Friedman, R.; Zhaunerchyk, V.; Bourenkov, G.; Schneider, T.; Stake, J.; Katona, G. 10.1101/475889 — biophysics — Posted on 2019-03-13 1972 Persistent anti-heart autoimmunity causes cardiomyocyte damage in chronic heart failure. Sintou, A.; el Rifai, S.; Mansfield, C.; Rothery, S.; Sanchez Alonso, J. L.; Narodden, S.; Sharma, K.; Ferraro, E.; Hasham, M. G.; Swiatlowska, P.; Harding, S. E.; Rosenthal, N.; Gorelik, J.; Sattler, S. 10.1101/542597 — immunology — Posted on 2019-03-13 1973 High-density spatial transcriptomics arrays for in situ tissue profiling Vickovic, S.; Eraslan, G.; Salmen, F.; Klughammer, J.; Stenbeck, L.; Aijo, T.; Bonneau, R.; Fernandez Navarro, J.; Bergenstraahle, L.; Gould, J.; Ronaghi, M.; Frisen, J.; Lundeberg, J.; Regev, A.; Staahl, P. L. 10.1101/563338 — genomics — Posted on 2019-03-13 1974 Self-reported Health is Related to Body Height and Waist Circumference in Rural Indigenous and Urbanized Latin-American Populations Leongomez, J. D.; Sanchez, O. R.; Vasquez-Amezquita, M.; Valderrama, E.; Castellanos-Chacon, A.; Morales-Sanchez, L.; Nieto, J.; Gonzalez-Santoyo, I. 10.1101/562942 — evolutionary biology — Posted on 2019-03-13 1975 A Quasi Birth-and-Death Model For Tumor Recurrence Santana, L. M.; Ganesan, S.; Bhanot, G. 10.1101/551770 — cancer biology — Posted on 2019-03-13 1976 Qtlizer: comprehensive QTL annotation of GWAS results Munz, M.; Wohlers, I.; Simon, E.; Busch, H.; Schaefer, A. S.; Erdmann, J. 10.1101/495903 — bioinformatics — Posted on 2019-03-13 1977 Confidence as a priority signal Aguilar-Lleyda, D.; Lemarchand, M.; de Gardelle, V. 10.1101/480350 — neuroscience — Posted on 2019-03-13 1978 Genotype-phenotype relationships in children with Copy Number Variants associated with high neuropsychiatric risk: Findings from the case-control IMAGINE-ID cohort in the United Kingdom Chawner, S.; Owen, M.; Holmans, P.; Raymond, L.; Skuse, D.; Hall, J.; van den Bree, M. 10.1101/535708 — genomics — Posted on 2019-03-13 1979 Adaptation and the Parliament of Genes Scott, T. W.; West, S. A. 10.1101/526970 — evolutionary biology — Posted on 2019-03-13 1980 Exploring neighborhoods in large metagenome assembly graphs reveals hidden sequence diversity Brown, C. T.; Moritz, D.; O'Brien, M.; Reidl, F.; Reiter, T.; Sullivan, B. 10.1101/462788 — bioinformatics — Posted on 2019-03-13 1981 Valid post-clustering differential analysis for single-cell RNA-Seq Zhang, J. M.; Kamath, G. M.; Tse, D. N. 10.1101/463265 — bioinformatics — Posted on 2019-03-13 1982 A high-throughput fluorescence-based assay for the detection of petroleum hydrocarbon degrading bacteria French, K. E.; Terry, N. 10.1101/498345 — microbiology — Posted on 2019-03-13 1983 Dysregulated Oscillatory Connectivity in the Visual System in Autism Spectrum Disorder Seymour, R. A.; Rippon, G.; Gooding-Williams, G.; Schoffelen, J.-M.; Kessler, K. 10.1101/440586 — neuroscience — Posted on 2019-03-13 1984 Attention explores space periodically at the theta frequency Senoussi, M.; Moreland, J. C.; Busch, N. A.; Dugue, L. 10.1101/443341 — neuroscience — Posted on 2019-03-13 1985 HIV/AIDS treatment failure and its associated factors in Ethiopia: Systematic review and meta-analysis Endalamaw, A.; Mekonnen, M.; Geremew, D.; Ambaw, F.; Tesera, H.; Habtewold, T. D. 10.1101/440743 — epidemiology — Posted on 2019-03-13 1986 Nanopore formation in the cuticle of an insect olfactory sensillum Ando, T.; Sekine, S.; Inagaki, S.; Misaki, K.; Badel, L.; Moriya, H.; Sami, M. M.; Itakura, Y.; Chihara, T.; Kazama, H.; Yonemura, S.; Hayashi, S. 10.1101/444729 — developmental biology — Posted on 2019-03-13 1987 uORF-Tools - Workflow for the determination of translation-regulatory upstream open reading frames Scholz, A.; Eggenhofer, F.; Gelhausen, R.; Grüning, B.; Zarnack, K.; Brüne, B.; Backofen, R.; Schmid, T. 10.1101/415018 — bioinformatics — Posted on 2019-03-13 1988 The intrinsic and regulated proteomes of barley seeds in response to fungal infection Kerr, E. D.; Phung, T. K.; Caboche, C. H.; Fox, G. P.; Platz, G. J.; Schulz, B. L. 10.1101/445916 — biochemistry — Posted on 2019-03-13 1989 Centromeric CENP-A loading requires accurate mitotic timing, which is linked to checkpoint proteins Pauleau, A.-L.; Bergner, A.; Kajtez, J.; Erhardt, S. 10.1101/394981 — cell biology — Posted on 2019-03-13 1990 Vertical and horizontal integration of multi-omics data with miodin Ulfenborg, B. 10.1101/431429 — bioinformatics — Posted on 2019-03-13 1991 Identification and Ranking of Recurrent Neo-Epitopes in Cancer Blanc, E.; Holtgrewe, M.; Dhamodaran, A.; Messerschmidt, C.; Willimsky, G.; Blankenstein, T.; Beule, D. 10.1101/389437 — genomics — Posted on 2019-03-13 1992 Integrating single-cell RNA-Seq with spatial transcriptomics in pancreatic ductal adenocarcinoma using multimodal intersection analysis Moncada, R.; Wagner, F.; Chiodin, M.; Devlin, J. C.; Baron, M.; Hajdu, C. H.; Simeone, D.; Yanai, I. 10.1101/254375 — cancer biology — Posted on 2019-03-13 1993 Superresolved microparticle traction force microscopy reveals subcellular force patterns in immune cell-target interactions Vorselen, D.; Wang, Y.; de Jesus, M. M.; Shah, P. K.; Footer, M. J.; Huse, M.; Cai, W.; Theriot, J. A. 10.1101/431221 — biophysics — Posted on 2019-03-13 1994 Genetic diversity of clinical Bordetella pertussis ST2 strains in comparison with vaccine reference strains of India Sharma, N. C.; Anandan, S.; Devanga Ragupathi, N. K.; Muthuirulandi Sethuvel, D. P.; Vasudevan, K.; Kumar, D.; Gupta, S. K.; Sangal, L.; Murugesan, V.; Veeraraghavan, B. 10.1101/573543 — microbiology — Posted on 2019-03-13 1995 A systematic evaluation of the design, orientation, and sequence context dependencies of massively parallel reporter assays Klein, J. C.; Agarwal, V.; Inoue, F.; Keith, A.; Martin, B.; Kircher, M.; Ahituv, N.; Shendure, J. 10.1101/576405 — genomics — Posted on 2019-03-13 1996 Diversification of the type IV filament super-family into machines for adhesion, secretion, DNA transformation and motility Denise, R.; Abby, S. S.; Rocha, E. P. 10.1101/576694 — evolutionary biology — Posted on 2019-03-13 1997 Dual RNA-Seq meta-analysis in Plasmodium infection Mukherjee, P.; Heitlinger, E. 10.1101/576116 — bioinformatics — Posted on 2019-03-13 1998 In silico learning of tumor evolution through mutational time series Auslander, N.; Wolf, Y. I.; Koonin, E. V. 10.1101/577171 — bioinformatics — Posted on 2019-03-13 1999 Encircling the regions of the pharmacogenomic landscape that determine drug response Fernandez-Torras, A.; Duran-Frigola, M.; Aloy, P. 10.1101/383588 — bioinformatics — Posted on 2019-03-13 2000 Nbs1 Mediates Assembly and Activity of the Mre11 complex Kim, J. H.; Penson, A. V.; Taylor, B. S.; Petrini, J. 10.1101/576082 — cancer biology — Posted on 2019-03-13 2001 Multi-task learning predicts drug combination synergy in cells and in the clinic Gilvary, C. M.; Dry, J. R.; Elemento, O. 10.1101/576017 — cancer biology — Posted on 2019-03-13 2002 Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density Siewe Fodjo, J. N.; Mandro, M. N.; Mukendi, D.; Tepage, F.; Menon, S.; Nakato, S.; Francoise, N.; Abhafule, G.; Wonya'rossi, D.; Anyolito, A.; Lokonda, R.; Hotterbeekx, A.; Colebunders, R. 10.1101/577247 — neuroscience — Posted on 2019-03-13 2003 No Evidence for Communication in the Complete Locked-in State Spueler, M. 10.1101/287631 — neuroscience — Posted on 2019-03-13 2004 In silico identification of novel peptides with antibacterial activity against multidrug resistant Staphylococcus aureus Oyama, L. B.; Olleik, H.; Teixeira, A. C. N.; Guidini, M. M.; Pickup, J. A.; Cookson, A. R.; Vallin, H.; Wilkinson, T.; Bazzolli, D.; Richards, J.; Wootton, M.; Mikut, R.; Hilpert, K.; Maresca, M.; Perrier, J.; Hess, M.; Mantovani, H. C.; Fernandez-Fuentes, N.; Creevey, C. J.; Huws, S. A. 10.1101/577221 — microbiology — Posted on 2019-03-13 2005 Cell-length heterogeneity: a population-level solution to growth/virulence trade-offs in the plant pathogen Dickeya dadantii Cui, Z.; Yang, C.-H.; Kharadi, R. R.; Yuan, X.; Sundin, G. W.; Triplett, L. R.; Wang, J.; Zeng, Q. 10.1101/577296 — microbiology — Posted on 2019-03-13 2006 Directed migration shapes cooperation in spatial ecological public goods games Funk, F. A.; Hauert, C. 10.1101/577205 — evolutionary biology — Posted on 2019-03-13 2007 Strategies based on sum of peak intensities may better reflect protein expression than peak area integration in iTRAQ protein expression measurement by LC-MS/MS using a TripleTOF 5600+ platform Burat, B.; Gonzalez, J.; Sauvage, F.-L.; Aouad, H.; Arnion, H.; Pinault, E.; Marquet, P.; Essig, M. 10.1101/577254 — cell biology — Posted on 2019-03-13 2008 SPHIRE-crYOLO: A fast and accurate fully automated particle picker for cryo-EM Wagner, T.; Merino, F.; Stabrin, M.; Moriya, T.; Antoni, C.; Apelbaum, A.; Hagel, P.; Sitsel, O.; Raisch, T.; Prumbaum, D.; Quentin, D.; Roderer, D.; Tacke, S.; Siebolds, B.; Schubert, E.; Shaikh, T. R.; Lill, P.; Gatsogiannis, C.; Raunser, S. 10.1101/356584 — biophysics — Posted on 2019-03-13 2009 The association between dietary habits and periodontal disease in young adult women Hosoda, A.; Komagamine, Y.; Kanazawa, M.; Hama, Y.; Kojo, A.; Minakuchi, S. 10.1101/577155 — pathology — Posted on 2019-03-13 2010 Human recombinant erythropoietin improves motor function in rats with spinal cord compression myelopathy Tanaka, T.; Murata, H.; Miyazaki, R.; Yoshizumi, T.; Sato, M.; Ohtake, M.; Tateishi, K.; Kim, P.; Yamamoto, T. 10.1101/577130 — neuroscience — Posted on 2019-03-13 2011 Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti Danet, L.; Beauclair, G.; Berthet, M.; Moratorio, G.; Gracias, S.; Tangy, F.; Choumet, V.; jouvenet, n. 10.1101/577213 — microbiology — Posted on 2019-03-13 2012 Co-occurrence of organic and inorganic N sources influences asparagine uptake and internal amino acid profiles in white clover Czaban, W.; Rasmussen, J. 10.1101/577114 — plant biology — Posted on 2019-03-13 2013 Effects of dietary taurine level on visual function in European sea bass (Dicentrarchus labrax) Brill, R.; Horodysky, A.; Place, A.; Larkin, M.; Reimschuessel, R. 10.1101/577023 — physiology — Posted on 2019-03-13 2014 Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, P53, Caspase-3 and Bcl-2 in STZ-induced diabetic rats Ahmed, O. M.; Ali, T. M.; Abdel Gaid, M. A.; Elberry, A. 10.1101/577106 — pharmacology and toxicology — Posted on 2019-03-13 2015 Towards a real-world brain-computer interface for image retrieval McCartney, B.; Martinez-del-Rincon, J.; Devereux, B.; Murphy, B. 10.1101/576983 — neuroscience — Posted on 2019-03-13 2016 Timing seed germination under changing salinity: a key role of the ERECTA receptor-kinases Nanda, A. K.; El Habti, A.; Hocart, C.; Masle, J. 10.1101/576512 — plant biology — Posted on 2019-03-13 2017 Uncovering mechanisms of global ocean change effects on the Dungeness crab (Cancer magister) through metabolomics analysis Trigg, S. A.; McElhany, P.; Maher, M.; Perez, D.; Busch, D. S.; Nichols, K. M. 10.1101/574798 — systems biology — Posted on 2019-03-13 2018 What’s in Your Body of Water? Reducing the Psychological Distance of Pharmaceutical Pollution through Metaphoric Framing in Risk Communication (A Pilot Study) Millarhouse, A. Z.; Vatovec, C.; Niles, M. T.; Ivakhiv, A. 10.1101/575639 — scientific communication and education — Posted on 2019-03-13 2019 Phylogenetic reclassification of vertebrate melatonin receptors to include Mel1d Macqueen, D. J.; Ebbesson, L. O. E.; Hazlerigg, D. G.; Denker, E. 10.1101/574384 — physiology — Posted on 2019-03-13 2020 %svy_logistic_regression: A generic SAS(R) macro for simple and multiple logistic regression and creating quality publication-ready tables using survey or non-survey data Muthusi, J.; Mwalili, S.; Young, P. 10.1101/575605 — bioinformatics — Posted on 2019-03-13 2021 Context-specific effects of facial dominance and trustworthiness on hypothetical leadership decisions Ferguson, H. S.; Owen, A.; Hahn, A.; Torrance, J.; DeBruine, L. M.; Jones, B. C. 10.1101/575597 — animal behavior and cognition — Posted on 2019-03-13 2022 Doberman pinschers present autoimmunity associated with functional autoantibodies: a model to study the autoimmune background of human dilated cardiomyopathy Schimke, I.; Wess, G.; Wallukat, G.; Fritscher, A.; Becker, N.-P.; Wenzel, K.; Müller, J. 10.1101/575613 — pathology — Posted on 2019-03-13 2023 Empirical examination of the replicability of associations between brain structure and psychological variables Kharabian, S.; Eickhoff, S.; Hoffstaedter, F.; Genon, S. 10.1101/496729 — neuroscience — Posted on 2019-03-13 2024 Morphofunctional deficits in the cerebral cortex of NeuroD2 mutant mice are associated with autism/schizophrenia-like behaviors Bugeon, S.; Lafi, S.; Beurrier, C.; Sahu, S.; Runge, K.; Schaller, F.; Loubat, A.; Mathieu, R.; Herault, L.; Gaillard, S.; Cahuc, M.; Pallesi-Pocachard, E.; Montheil, A.; Bosio, A.; Represa, A.; Cardoso, C.; Cremer, H.; de Chevigny, A. 10.1101/296889 — neuroscience — Posted on 2019-03-13 2025 Prevalence of parasitic infections among recent immigrants to Chicago Herrick, J. A.; Nordstrom, M.; Maloney, P.; Rodriguez, M.; Naceanceno, K.; Enamorado, G. G.; Mejia, R.; Hershow, R. 10.1101/575779 — epidemiology — Posted on 2019-03-13 2026 Hierarchical temporal prediction captures motion processing from retina to higher visual cortex Singer, Y.; Willmore, B. D.; King, A. J.; Harper, N. S. 10.1101/575464 — neuroscience — Posted on 2019-03-13 2027 Looking for a reference for large datasets: relative reliability of visual and automatic sleep scoring Berthomier, C.; Muto, V.; Schmidt, C.; Vandewalle, G.; Jaspar, M.; Devillers, J.; Gaggioni, G.; Chellappa, S.; Meyer, C.; Phillips, C.; Salmon, E.; Berthomier, P.; Prado, J.; Benoit, O.; Brandewinder, M.; Mattout, J.; Maquet, P. 10.1101/576090 — neuroscience — Posted on 2019-03-13 2028 Effect of Interpopulation Spike-Timing-Dependent Plasticity on Synchronized Rhythms in Neuronal Networks with Inhibitory and Excitatory Populations Kim, S.-Y.; Lim, W. 10.1101/576314 — neuroscience — Posted on 2019-03-13 2029 Rapid recalibration of temporal order judgements: Response bias accounts for contradictory results Keane, B.; Bland, N. S.; Matthews, N.; Carroll, T. J.; Wallis, G. 10.1101/576249 — neuroscience — Posted on 2019-03-13 2030 The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast Serbyn, N.; Noireterre, A.; Bagdiul, I.; Plank, M.; Michel, A. H.; Loewith, R.; Kornmann, B.; Stutz, F. 10.1101/575860 — molecular biology — Posted on 2019-03-13 2031 Biotic interactions affect fitness across latitudes, but only drive local adaptation in the tropics Hargreaves, A.; Germain, R.; Bontrager, M.; Persi, J.; Angert, A. 10.1101/575498 — evolutionary biology — Posted on 2019-03-13 2032 Frequent birth of de novo genes in the compact yeast genome Blevins, W. R.; Ruiz-Orera, J.; Messeguer, X.; Blasco-Moreno, B.; Villanueva-Canas, J. L.; Espinar, L.; Diez, J.; Carey, L.; Alba, M. M. 10.1101/575837 — evolutionary biology — Posted on 2019-03-13 2033 Best practices for making reliable inferences from citizen science data: case study using eBird to estimate species distributions Johnston, A.; Hochachka, W. M.; Strimas-Mackey, M.; Ruiz Gutierrez, V.; Robinson, O. J.; Miller, E. T.; Auer, T.; Kelling, S. T.; Fink, D. 10.1101/574392 — ecology — Posted on 2019-03-13 2034 CMKLR1-targeting peptide tracers for PET/MR imaging of breast cancer Erdmann, S.; Niederstadt, L.; Koziolek, E. J.; Castillo Gomez, J. D.; Prasad, S.; Wagener, A.; von Hacht, J. L.; Hallmann, S.; Exner, S.; Bandholtz, S.; Beindorff, N.; Brenner, W.; Groetzinger, C. 10.1101/575902 — cancer biology — Posted on 2019-03-13 2035 Germline genetic determination of cancer progression and survival Ostendorf, B. N.; Tafreshian, K. N.; Adaku, N.; Bilanovic, J.; Tavora, B.; Tavazoie, S. F. 10.1101/576181 — cancer biology — Posted on 2019-03-13 2036 Neural measures of subsequent memory reflect endogenous variability in cognitive function Weidemann, C. T.; Kahana, M. 10.1101/576173 — neuroscience — Posted on 2019-03-13 2037 Send-receive communication asymmetry in brain networks: Inferring directionality of neural signalling from undirected structural connectomes Seguin, C.; Razi, A.; Zalesky, A. 10.1101/573071 — neuroscience — Posted on 2019-03-13 2038 The microbiota regulates inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination McMurran, C.; Guzman de la Fuente, A.; Penalva, R.; Menachem-Zidon, O.; Dombrowski, Y.; Gonzalez, G.; Zhao, C.; Krause, F.; Young, A.; Griffin, J.; Jones, C.; Hollins, C.; Heimesaat, M.; Fitzgerald, D.; Franklin, R. 10.1101/575829 — neuroscience — Posted on 2019-03-13 2039 Supra-threshold perception and neural representation of tones presented in noise in conditions of masking release Egger, K.; Dau, T.; Epp, B. 10.1101/575720 — neuroscience — Posted on 2019-03-13 2040 Sequencing Complete Genomes of RNA Viruses With MinION Nanopore: Finding Associations Between Mutations Harel, N.; Meir, M.; Gophna, U.; Stern, A. 10.1101/575480 — genetics — Posted on 2019-03-13 2041 Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications liau, y.; Maggo, S.; Miller, A. L.; Pearson, J. F.; Kennedy, M. A.; Cree, S. L. 10.1101/576280 — genetics — Posted on 2019-03-13 2042 Dynamic and synergistic influences of air temperature and rainfall on general flowering in a Bornean lowland tropical forest Ushio, M.; Osada, Y.; Kumagai, T.; Kume, T.; Sylvester Pungga, R.; Nakashizuka, T.; Itioka, T.; Sakai, S. 10.1101/576231 — ecology — Posted on 2019-03-13 2043 Ligand-independent role of ErbB3 in endocytotic recycling Saez-Ibanez, A. R.; Scheffler, J. M.; Terabayashi, T.; Idevall, O.; Ferby, I. 10.1101/575449 — cell biology — Posted on 2019-03-13 2044 Rosa26 docking sites for investigating genetic circuit silencing in stem cells Fitzgerald, M.; Gibbs, C.; Deans, T. 10.1101/575266 — cell biology — Posted on 2019-03-13 2045 Characterization and repurposing of the endogenous Type I-F CRISPR-Cas system of Zymomonas mobilis for genome engineering Zheng, Y.; Han, J.; Liang, W.; Li, R.; Hu, X.; Wang, B.; Shen, W.; Ma, X.; Ma, L.; Yi, L.; Yang, S.; Peng, W. 10.1101/576355 — bioengineering — Posted on 2019-03-13 2046 Identification of master regulators in goblet cells and Paneth cells using transcriptomics profiling of gut organoids and multi-layered networks Treveil, A.; Sudhakar, P.; Matthews, Z. J.; Wrzesinski, T.; Jones, E. J.; Olbei, M.; Hautefort, I.; Hall, L. J.; Carding, S. R.; Mayer, U.; Powell, P. P.; Wileman, T.; Di Palma, F.; Haerty, W.; Korcsmaros, T. 10.1101/575845 — systems biology — Posted on 2019-03-13 2047 Coordinated development of the mouse extrahepatic bile duct: implications for neonatal susceptibility to biliary injury Khandekar, G.; Llewellyn, J.; Kriegermeier, A.; Waisbourd-Zinman, O.; Johnson, N.; Du, Y.; Giwa, R.; Liu, X.; Kisseleva, T.; Russo, P. A.; Theise, N. D.; Wells, R. G. 10.1101/576256 — physiology — Posted on 2019-03-13 2048 Pore-modulating toxins exploit inherent slow inactivation to block K+ channels Karbat, I.; Altman-Gueta, H.; Fine, S.; Szanto, T.; Hamer-Rogotner, S.; Dym, O.; Frolow, F.; Gordon, D.; Panyi, G.; Gurevitz, M.; Reuveny, E. 10.1101/576132 — pharmacology and toxicology — Posted on 2019-03-13 2049 Acetylcholine release inhibits distinct excitatory inputs onto hippocampal CA1 pyramidal neurons via different cellular and network mechanisms Goswamee, P.; McQuiston, R. 10.1101/575811 — neuroscience — Posted on 2019-03-13 2050 Single and population coding of taste in the gustatory cortex of awake mice Levitan, D.; Lin, J.-Y.; Wachutka, J.; Mukherjee, N.; Nelson, S. B.; Katz, D. B. 10.1101/575522 — neuroscience — Posted on 2019-03-13 2051 A validated workflow for rapid taxonomic assignment and monitoring of a national fauna of bees (Apiformes) using high throughput barcoding Creedy, T. J.; Norman, H.; Tang, C. Q.; Chin, K. Q.; Andujar, C.; Arribas, P.; O'Connor, R.; Carvell, C.; Notton, D. G.; Vogler, A. P. 10.1101/575308 — molecular biology — Posted on 2019-03-13 2052 Dual activity of PNGM-1, a metallo-β-lactamase and tRNase Z, pinpoints the evolutionary origin of subclass B3 metallo-β-lactamases Lee, J. H.; Takahashi, M.; Jeon, J. H.; Kang, L.-W.; Seki, M.; Park, K. S.; Hong, M.-K.; Park, Y. S.; Kim, T. Y.; Karim, A. M.; Lee, J.-H.; Nashimoto, M.; Lee, S. H. 10.1101/575373 — microbiology — Posted on 2019-03-13 2053 Minimally-invasive nasal sampling in children offers accurate pneumococcal colonization detection Nikolaou, E.; Blizard, A.; Pojar, S.; Mitsi, E.; German, E. L.; Reine, J.; Hill, H.; McNamara, P. S.; Collins, A. M.; Ferreira, D. M.; Jochems, S. P. 10.1101/573196 — microbiology — Posted on 2019-03-13 2054 The quail as an avian model system: its genome provides insights into social behaviour, seasonal biology and infectious disease response Morris, K.; Hindle, M. M.; Boitard, S.; Burt, D. W.; Danner, A. F.; Eory, L.; Forrest, H. L.; Gourichon, D.; Gros, J.; Hillier, L.; Jaffredo, T.; Khoury, H.; Lansford, R.; Leterrier, C.; Loudon, A.; Mason, A. S.; Meddle, S. L.; Minvielle, F.; Minx, P.; Pitel, F.; Seiler, J. P.; Shimmura, T.; Tomlinson, C.; Vignal, A.; Webster, R. G.; Yoshimura, T.; Warren, W. C.; Smith, J. 10.1101/575332 — genomics — Posted on 2019-03-13 2055 Optimisation of rapid STR analysis using a standard DNA forensic pipeline Gammon, K. S.; Mayers, C. N. 10.1101/575357 — genetics — Posted on 2019-03-13 2056 Single-base mapping of m6A by an antibody-independent method Zhang, Z.; Chen, L.-Q.; Zhao, Y.-L.; Yang, C.-G.; Roundtree, I. A.; Zhang, Z.; Ren, J.; Xie, W.; He, C.; Luo, G.-Z. 10.1101/575555 — genetics — Posted on 2019-03-13 2057 A Bayesian Approach for Inferring the Impact of a Discrete Character on Rates of Continuous-Character Evolution in the Presence of Background Rate Variation May, M. R.; Moore, B. R. 10.1101/576207 — evolutionary biology — Posted on 2019-03-13 2058 Contrasting population genetic structure in Acropora coral hosts and their algal symbionts across multiple spatial scales Davies, S. W.; Wham, D.; Kanke, M.; Matz, M. 10.1101/575183 — ecology — Posted on 2019-03-13 2059 PINK1-parkin-mediated mitophagy generates stereotyped somatic mosaicism of the mitochondrial genome Ahier, A.; Dai, C.-Y.; Zuryn, S. 10.1101/576165 — cell biology — Posted on 2019-03-13 2060 LTK is an ER-resident receptor tyrosine kinase that regulates secretion Centonze, F. G.; Reiterer, V.; Nalbach, K.; Saito, K.; Pawlowski, K.; Behrends, C.; Farhan, H. 10.1101/575365 — cell biology — Posted on 2019-03-13 2061 Bone morphogenetic protein 4 gene therapy in mice inhibits myeloma tumor growth, but has a negative impact on bone Westhrin, M.; Holien, T.; Zahoor, M.; Moen, S. H.; Buene, G.; Stordal, B.; Hella, H.; Yuan, H.; de Bruijn, J. D.; Martens, A.; Groen, R. W.; Bosch, F.; Smith, U.; Sponaas, A. M.; Sundan, A.; Standal, T. 10.1101/575159 — cancer biology — Posted on 2019-03-13 2062 Glioblastomas derived from genetically modified pluripotent stem cells recapitulate pathobiology Koga, T.; Benitez, J. A.; Chaim, I. A.; Markmiller, S.; Parisian, A. D.; Turner, K. M.; Hessenauer, F. M.; D'Antonio, M.; Nguyen, N.-p. D.; Saberi, S.; Ma, J.; Miki, S.; Boyer, A. D.; Ravits, J.; Frazer, K. A.; Bafna, V.; Chen, C. C.; Mischel, P. S.; Yeo, G. W.; Furnari, F. B. 10.1101/576009 — cancer biology — Posted on 2019-03-13 2063 A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic aberration based molecular signatures Diossy, M.; Sztupinszki, Z.; Borcsok, J.; Krzystanek, M.; Tisza, V.; Spisak, S.; Rusz, O.; Csabai, I.; Moldvay, J.; Pedersen, A. G.; Szuts, D.; Szallasi, Z. 10.1101/576223 — cancer biology — Posted on 2019-03-13 2064 The roles of microtubules and membrane tension in axonal beading, retraction, and atrophy Datar, A.; Ameeramja, J.; Bhat, A.; Srivastava, R.; Bernal, R.; Prost, J.; Callan-Jones, A.; Pullarkat, P. A. 10.1101/575258 — biophysics — Posted on 2019-03-13 2065 MALVA: genotyping by Mapping-free ALlele detection of known VAriants Bernardini, G.; Bonizzoni, P.; Denti, L.; Previtali, M.; Schönhuth, A. 10.1101/575126 — bioinformatics — Posted on 2019-03-13 2066 CytoGPS: A Web-Enabled Karyotype Analysis Tool for Cytogenetics Abrams, Z. B.; Zhang, L.; Abruzzo, L. V.; Heerema, N. A.; Li, S.; Dillon, T.; Rodriguez, R.; Coombes, K.; Payne, P. R. O. 10.1101/575423 — bioinformatics — Posted on 2019-03-13 2067 Rapid RNA sequencing data analysis using serverless computing Hung, L.-H.; Kumanov, D.; Niu, X.; Lloyd, W.; Yeung, K. Y. 10.1101/576199 — bioinformatics — Posted on 2019-03-13 2068 Decentralized Distribution-sampled Classification Models with Application to Brain Imaging Lewis, N.; Gazula, H.; Plis, S.; calhoun, v. 10.1101/576108 — bioinformatics — Posted on 2019-03-13 2069 Engineered phenotype patterns in microbial populations Bittihn, P.; Didovyk, A.; Tsimring, L. S.; Hasty, J. 10.1101/575068 — synthetic biology — Posted on 2019-03-13 2070 Chrysin, but not the flavone backbone, decreases anxiety-like behavior in animal tests Ponciano, L. J.; Costa, B. P.; Feitosa, L. M.; Campos, K. S.; Chaves, S. N.; Cueto-Escobedo, J.; Lima-Maximino, M. G.; Rodriguez-Landa, J. F.; Maximino, C. 10.1101/575514 — pharmacology and toxicology — Posted on 2019-03-13 2071 A genetically adaptable strategy for ribose scavenging in a human gut symbiont plays a diet-dependent role in colon colonization Glowacki, R.; Pudlo, N.; Tuncil, Y.; Luis, A.; Terekhov, A.; Hamaker, B.; Martens, E. 10.1101/574913 — microbiology — Posted on 2019-03-13 2072 The enemy from within: a prophage of Roseburia intestinalis systematically turns lytic in the mouse gut, driving bacterial adaptation by CRISPR spacer acquisition Cornuault, J. K.; Moncaut, E.; Loux, V.; Mathieu, A.; Sokol, H.; Petit, M.-A.; De Paepe, M. 10.1101/575076 — microbiology — Posted on 2019-03-13 2073 Non-lethal oxidative stress boosts bacterial survival and evolvability under lethal exposure Rodriguez Rojas, A.; Kim, J.; Johnston, P. R.; Makarova, O.; Eravci, M.; Weise, C.; Hengge, R.; Rolff, J. 10.1101/575134 — evolutionary biology — Posted on 2019-03-13 2074 Multi-enhancer transcriptional hubs confer phenotypic robustness Tsai, A.; Alves, M.; Crocker, J. 10.1101/575175 — developmental biology — Posted on 2019-03-13 2075 Maximum Likelihood Reconstruction of Ancestral Networks by Integer Linear Programming Rajan, V.; Kingsford, C.; Zhang, X. 10.1101/574814 — bioinformatics — Posted on 2019-03-13 2076 TrackUSF, a novel methodology for automated analysis of ultrasonic vocalizations, reveals modified social communication in a rat model of autism Netser, S.; Nahardiya, G.; Weiss-Dicker, G.; Dadush, R.; Goussha, Y.; Harony-Nicolas, H.; Cohen, L.; Crammer, K.; Wagner, S. 10.1101/575191 — animal behavior and cognition — Posted on 2019-03-13 2077 Machine learning Classification of Dyslexic Children based on EEG Local Network Features Rezvani, Z.; Zare, M.; Zaric, G.; Bonte, M.; Tijms, J.; Van der Molen, M. W.; Fraga Gonzalez, G. 10.1101/569996 — neuroscience — Posted on 2019-03-13 2078 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth Galdi, P.; Blesa, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P. 10.1101/569319 — neuroscience — Posted on 2019-03-12 2079 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440 Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J. 10.1101/567529 — microbiology — Posted on 2019-03-12 2080 The bacterial endosymbiont Wolbachia increases reproductive investment and accelerates the life cycle of ant colonies SINGH, R.; Linksvayer, T. A. 10.1101/574921 — evolutionary biology — Posted on 2019-03-12 2081 The fitness cost and benefit of phase separated protein deposits Sanchez de Groot, N.; Torrent Burgas, M.; Ravarani, C. N. J.; Trusina, A.; Ventura, S.; Babu, M. 10.1101/574657 — systems biology — Posted on 2019-03-12 2082 Activity-dependent changes in synaptic protein complex composition are consistent in different detergents despite differential solubility Lautz, J. D.; Gniffke, E. P.; Brown, E. A.; Immendorf, K. B.; Mendel, R. D.; Smith, S. E. P. 10.1101/576074 — neuroscience — Posted on 2019-03-12 2083 Visual recognition of the female body axis drives spatial elements of male courtship in Drosophila melanogaster McKinney, R.; Ben-Shahar, Y. 10.1101/576322 — neuroscience — Posted on 2019-03-12 2084 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps Moritz, S.; Pfab, J.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L.; Si, D. 10.1101/572990 — molecular biology — Posted on 2019-03-12 2085 Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology Mesman, A. W.; Soto, M.; Coit, J.; Calderon, R.; Aliaga, J.; Pollock, N. R.; Mendoza, M.; Mestanza, F. M.; Mendoza, C. J.; Murray, M. B.; Lecca, L.; Holmberg, R.; Franke, M. F. 10.1101/564088 — microbiology — Posted on 2019-03-12 2086 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J. 10.1101/574426 — genetics — Posted on 2019-03-12 2087 Cultured pluripotent planarian stem cells retain potency and express proteins from exogenously introduced mRNAs Lei, K.; McKinney, S. A.; Ross, E. J.; Lee, H.-C.; Sanchez Alvarado, A. 10.1101/573725 — cell biology — Posted on 2019-03-12 2088 The life of P.I. - Transitions to Independence in Academia Acton, S. E.; Bell, A.; Toseland, C. P.; Twelvetrees, A. 10.1101/571935 — scientific communication and education — Posted on 2019-03-12 2089 M1 disruption delays motor processes but not deliberation about action choices Derosiere, G.; Thura, D.; Cisek, P.; Duque, J. 10.1101/501205 — neuroscience — Posted on 2019-03-12 2090 CHIME: CMOS-hosted in-vivo microelectrodes for massively scalable neuronal recordings Kollo, M.; Racz, R. R.; Hanna, M.--E. S.; Obaid, A. M.; Angle, M. R.; Wray, W.; Kong, Y.; Hierlemann, A.; Muller, J.; Melosh, N. A.; Schaefer, A. T. 10.1101/570069 — neuroscience — Posted on 2019-03-12 2091 Learning-accelerated Discovery of Immune-Tumour Interactions Ozik, J.; Collier, N.; Heiland, R.; Macklin, P. 10.1101/573972 — systems biology — Posted on 2019-03-12 2092 Automated and Manual Quantification of Tumour Cellularity in Digital Slides for Tumour Burden Assessment Akbar, S.; Peikari, M.; Salama, S.; Panah, A. Y.; Nofech-Momes, S.; Martel, A. L. 10.1101/571190 — pathology — Posted on 2019-03-12 2093 Insights into an alternative pathway for glycerol metabolism in a glycerol kinase deficient Pseudomonas putida KT2440 Walsh, M.; Casey, W.; Kenny, S. T.; Narancic, T.; Blank, L. M.; Wierckx, N.; Ballerstedt, H.; O Connor, K. E. 10.1101/567230 — microbiology — Posted on 2019-03-12 2094 Assessing graph-based read mappers against a novel baseline approach highlights strengths and weaknesses of the current generation of methods Grytten, I.; Rand, K. D.; Nederbragt, A. J.; Sandve, G. K. 10.1101/538066 — bioinformatics — Posted on 2019-03-12 2095 Vigour/tolerance trade-off in cultivated sunflower (Helianthus annuus) response to salinity stress is linked to leaf elemental composition Temme, A.; Kerr, K. L.; Donovan, L. A. 10.1101/447128 — plant biology — Posted on 2019-03-12 2096 A comparison of two mathematical models of the cerebrospinal fluid dynamics Donatelli, D.; Marcati, P.; Romagnoli, L. 10.1101/573337 — neuroscience — Posted on 2019-03-12 2097 Differential Tractography as a Track-Based Biomarker for Neurodegeneration Yeh, F.-C.; Zaydan, I. M.; Suski, V. R.; Lacomis, D.; Richardson, R. M.; Maroon, J.; Barrios-Martinez, J. 10.1101/576025 — neuroscience — Posted on 2019-03-12 2098 Intrinsic Cell-type Selectivity and Inter-neuronal Connectivity Alteration by Transcranial Focused Ultrasound Yu, K.; Niu, X.; Krook-Magnuson, E.; He, B. 10.1101/576066 — neuroscience — Posted on 2019-03-12 2099 Non-linear effects of socioeconomic status on brain development: associations between parental occupation, cortical thickness and language skills in childhood and adolescence Khundrakpam, B.; Choudhury, S.; Vainik, U.; Al-Sharif, N.; Bhutani, N.; Evans, A.; Pediatric Imaging, Neurocognition and Genetics Stu, 10.1101/575993 — neuroscience — Posted on 2019-03-12 2100 Estimating relatedness between malaria parasites Taylor, A. R.; Jacob, P. E.; Neafsey, D. E.; Buckee, C. O. 10.1101/575985 — genetics — Posted on 2019-03-12 2101 The gene annotated by the locus tag At3g08860 encodes a β-alanine/L-alanine aminotransferase in Arabidopsis thaliana Parthasarathy, A.; Savka, F. C.; Hudson, A. O. 10.1101/576041 — plant biology — Posted on 2019-03-12 2102 Refinement of the primate corticospinal pathway during prenatal development Ribeiro Gomes, A. R.; Olivier, E.; Killackey, H. P.; Giroud, P.; Berland, M.; Knoblauch, K.; Dehay, C.; Kennedy, H. 10.1101/575936 — neuroscience — Posted on 2019-03-12 2103 Watered-down biodiversity? A comparison of metabarcoding results from DNA extracted from matched water and bulk tissue biomonitoring samples Hajibabaei, M.; Porter, T.; Robinson, C.; Baird, D.; Shokralla, S.; Wright, M. 10.1101/575928 — ecology — Posted on 2019-03-12 2104 Population dynamics and age-dependent mortality processes in tropical reptiles Cayuela, H.; Akani, G. C.; Hema, E. M.; Eniang, E. A.; Amadi, N.; Ajong, S. N.; Dendi, D.; Petrozzi, F.; Luiselli, L. 10.1101/575977 — ecology — Posted on 2019-03-12 2105 Btbd6-dependent Plzf recruitment to Cul3 E3 ligase complexes through BTB domain heterodimerization Ismail, M. S.; Martin, S. R.; Ball, N. J.; Taylor, I. A.; Howell, S.; Wilkinson, D. G.; Smerdon, S. J. 10.1101/575910 — biochemistry — Posted on 2019-03-12 2106 SurfaceGenie: A web-based application for integrating predictive and experimental data for rational candidate surface marker prioritization Waas, M.; Terai Snarrenberg, S.; Littrell, J.; Jones Lipinski, R.; Hansen, P.; Corbett, J.; Gundry, R. 10.1101/575969 — systems biology — Posted on 2019-03-12 2107 ARMOR: an Automated Reproducible MOdular workflow for preprocessing and differential analysis of RNA-seq data Orjuela, S.; Huang, R.; Hembach, K.; Robinson, M.; Soneson, C. 10.1101/575951 — bioinformatics — Posted on 2019-03-12 2108 Inter-ecosystem variation in the food-collection behaviour in climbing perch Anabas testudineus, a freshwater fish VV, B.; V B, R.; Sinha, A. 10.1101/573600 — animal behavior and cognition — Posted on 2019-03-12 2109 The symmetrical pattern of base-pair substitution rates across the chromosome in Escherichia coli has multiple causes Niccum, B. A.; Lee, H.; MohammedIsmail, W.; Tang, H.; Foster, P. L. 10.1101/523696 — microbiology — Posted on 2019-03-12 2110 The genetic architecture of sporadic and recurrent miscarriage Laisk, T.; Soares, A. L. G.; Ferreira, T.; Painter, J. N.; Laber, S.; Bacelis, J.; Chen, C.-Y.; Lepamets, M.; Lin, K.; Liu, S.; Millwood, I. Y.; Ramu, A.; Southcombe, J.; Andersen, M. S.; Yang, L.; Becker, C. M.; Gordon, S. D.; Byberg-Grauholm, J.; Helgeland, O.; Hougaard, D. M.; Jin, X.; Johansson, S.; Juodakis, J.; Kartsonaki, C.; Kukushkina, V.; Lind, P. A.; Metspalu, A.; Montgomery, G. W.; Morris, A. P.; Mortensen, P. B.; Njolstad, P. R.; Nyholt, D. R.; Lippincott, M.; Seminara, S.; Salumets, A.; Snieder, H.; Zondervan, K.; Chen, Z.; Conrad, D. F.; Jacobsson, B.; Li, L.; Martin, N. G.; Nea 10.1101/575167 — genetics — Posted on 2019-03-12 2111 Chronic aromatase inhibition increases ventral hippocampal neurogenesis in middle-aged female mice Chaiton, J.; Wong, S.; Galea, L. 10.1101/434662 — neuroscience — Posted on 2019-03-12 2112 Adaptation of human iPSC-derived cardiomyocytes to tyrosine kinase inhibitors reduces acute cardiotoxicity via metabolic reprogramming Wang, H.; Sheehan, R. P.; Palmer, A. C.; Everley, R. A.; Boswell, S. A.; Ron-Harel, N.; Ringel, A. E.; Holton, K. M.; Jacobson, C. A.; Erickson, A. R.; Maliszewski, L.; Haigis, M. C.; Sorger, P. K. 10.1101/365841 — pharmacology and toxicology — Posted on 2019-03-12 2113 Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes Yamasaki, R.; Song, S.; Benedik, M.; Wood, T. K. 10.1101/486985 — microbiology — Posted on 2019-03-12 2114 Network organization of antibody interactions in sequence and structure space: the RADARS model Prechl, J. 10.1101/438804 — systems biology — Posted on 2019-03-12 2115 Frontal and parietal alpha oscillations reflect attentional modulation of cross-modal matching Misselhorn, J.; Friese, U.; Engel, A. K. 10.1101/477034 — neuroscience — Posted on 2019-03-12 2116 Virtual ChIP-seq: Predicting transcription factor binding by learning from the transcriptome Karimzadeh, M.; Hoffman, M. M. 10.1101/168419 — bioinformatics — Posted on 2019-03-12 2117 Connectivity profile of thalamic deep brain stimulation to effectively treat essential tremor Al-Fatly, B.; Ewert, S.; Kuebler, D.; Kroneberg, D.; Horn, A.; Kuehn, A. A. 10.1101/575209 — neuroscience — Posted on 2019-03-12 2118 A multi-state model of the CaMKII dodecamer suggests a role for calmodulin in maintenance of autophosphorylation Pharris, M. C.; Bartol, T. M.; Sejnowski, T. J.; Kennedy, M. B.; Stefan, M. I.; Kinzer-Ursem, T. L. 10.1101/575712 — neuroscience — Posted on 2019-03-12 2119 NGF-mediated photoablation of nociceptors reduces pain behavior in mice Nocchi, L.; Portulano, C.; Franciosa, F.; Doleschall, B.; Panea, M.; Roy, N.; Maffei, M.; Gargano, A.; Perlas, E.; Heppenstall, P. 10.1101/575274 — neuroscience — Posted on 2019-03-12 2120 A consensus set of genetic vulnerabilities to ATR inhibition Hustedt, N.; Alvarez-Quilon, A.; McEwan, A.; Yuan, J. Y.; Cho, T.; Koob, L.; Hart, T.; Durocher, D. 10.1101/574533 — molecular biology — Posted on 2019-03-12 2121 The gut microbiota regulates mouse biliary regenerative responses Liu, W.; Yan, C.; Zhang, B.; Chen, R.; Yu, Q.; Li, X.; Zhang, Y.; Hua, H.; Wei, Y.; Kou, Y.; Liu, Z.; Tang, R.; Zheng, K.; Wang, Y. 10.1101/575050 — microbiology — Posted on 2019-03-12 2122 Combining genetic crosses and pool targeted DNA-seq for untangling genomic variations associated with resistance to multiple insecticides in the dengue vector Aedes aegypti Cattel, J.; Faucon, F.; Leperon, B.; Sherpa, S.; Monchal, M.; Grillet, L.; Gaude, T.; Laporte, F.; Dusfour, I.; Reynaud, s.; David, J.-P. 10.1101/575753 — genomics — Posted on 2019-03-12 2123 Reproductive success of Eastern Bluebirds (Sialia sialis) varies with the timing and severity of drought Carleton, R. E.; Graham, J. H.; Lee, A.; Taylor, Z. P.; Carleton, J. F. 10.1101/575647 — ecology — Posted on 2019-03-12 2124 Deep Learning on Chaos Game Representation for Proteins Loechel, H. F.; Eger, D.; Sperlea, T.; Heider, D. 10.1101/575324 — bioinformatics — Posted on 2019-03-12 2125 Viral host prediction with Deep Learning Mock, F.; Viehweger, A.; Barth, E.; Marz, M. 10.1101/575571 — bioinformatics — Posted on 2019-03-12 2126 Lumen expansion facilitates epiblast-primitive endoderm fate specification in the mouse blastocyst formation. Ryan, A. Q.; Chan, C. J.; Graner, F.; Hiiragi, T. 10.1101/575282 — developmental biology — Posted on 2019-03-12 2127 A Probabilistic Programming Approach to Protein Structure Superposition Sanz Moreta, L.; Al-Sibahi, A. S. S.; Hamelryck, T.; Theobald, D.; Rommes, B. N.; Bullock, W.; Manoukian, A. 10.1101/575431 — bioinformatics — Posted on 2019-03-12 2128 Bcl-xL dynamics and cancer-associated mutations under the lens of protein structure networks and biomolecular simulations Sora, V.; Papaleo, E. 10.1101/574699 — bioinformatics — Posted on 2019-03-12 2129 COALIA: a computational model of human EEG for consciousness research Bensaid, S.; Modolo, J.; Merlet, I.; Wendling, F.; Benquet, P. 10.1101/575043 — neuroscience — Posted on 2019-03-12 2130 Flow arrest in the plasma membrane Chein, M.; Perlson, E.; Roichman, Y. 10.1101/575456 — biophysics — Posted on 2019-03-12 2131 Chestnut extract but not sodium salicylate decrease the severity of diarrhea and enterotoxigenic Escherichia coli F4 shedding in artificially infected piglets Girard, M.; Hu, D.; Pradervand, N.; Neuenschwander, S.; Bee, G. 10.1101/575662 — physiology — Posted on 2019-03-12 2132 Effects of persistent sodium current blockade in respiratory circuits depend on the pharmacological mechanism of action and network dynamics Phillips, R. S.; Rubin, J. E. 10.1101/575688 — neuroscience — Posted on 2019-03-12 2133 There is no single functional atlas even for a single individual: Parcellation of the human brain is state dependent Salehi, M.; Greene, A. S.; Karbasi, A.; Shen, X.; Scheinost, D.; Constable, R. T. 10.1101/431833 — neuroscience — Posted on 2019-03-12 2134 The effects of habits on motor skill learning Popp, N. J.; Yokoi, A.; Gribble, P. L.; Diedrichsen, J. 10.1101/338749 — neuroscience — Posted on 2019-03-12 2135 Challenging the point neuron dogma: FS basket cells as 2-stage nonlinear integrators Tzilivaki, A.; Kastellakis, G.; Poirazi, P. 10.1101/251314 — neuroscience — Posted on 2019-03-12 2136 Preliminary evidence that maternal immune activation specifically increases diagonal domain volume in the rat brain during early postnatal development Wood, T. C.; Edye, M. E.; Harte, M. K.; Neill, J. C.; Prinssen, E. P.; Vernon, A. C. 10.1101/432450 — neuroscience — Posted on 2019-03-12 2137 Infection with a small intestinal helminth Heligmosomoides polygyrus bakeri consistently alters microbial communities throughout the small and large intestine Harris, N.; Rapin, A.; Chuat, A.; Zaiss, M.; Lebon, L.; Marsland, B. 10.1101/575787 — microbiology — Posted on 2019-03-12 2138 Establishment of an orthodontic retention mouse model and the effect of anti-c-Fms antibody on orthodontic relapse Qi, J.; Kitaura, H.; Shen, W.-r.; Kishikawa, A.; Ogawa, S.; Ohori, F.; Noguchi, T.; Marahleh, A.; Nara, Y.; Mizoguchi, I. 10.1101/575589 — immunology — Posted on 2019-03-12 2139 Impact of Direct Acting Antivirals on Survival in Patients with Chronic Hepatitis C and Hepatocellular Carcinoma Kamp, W. M.; Sellers, C. M.; Stein, S. M.; Lim, J. K.; Kim, H. S. 10.1101/575670 — immunology — Posted on 2019-03-12 2140 CNEr: a toolkit for exploring extreme noncoding conservation Tan, G.; Polychronopoulos, D.; Lenhard, B. 10.1101/575704 — genomics — Posted on 2019-03-12 2141 A RID-like cytosine methyltransferase homologue controls sexual development in the fungus Podospora anserina Grognet, P.; Timpano, H.; Carlier, F.; Aït-Benkhali, J.; Berteaux-Lecellier, V.; Debuchy, R.; Bidard, F.; Malagnac, F. 10.1101/575746 — genetics — Posted on 2019-03-12 2142 Potential risk factors associated with human cystic echinococcosis: a semi-structured questionnaire from a large population-based ultrasound cross-sectional study in Eastern Europe and Turkey Tamarozzi, F.; Akhan, O.; Cretu, C. M.; Vutova, K.; Fabiani, M.; Orsten, S.; Pezzotti, P.; Popa, L. G.; Velev, V.; Siles-Lucas, M.; Brunetti, E.; Casulli, A. 10.1101/575761 — epidemiology — Posted on 2019-03-12 2143 MTH1 promotes mitotic progression to avoid oxidative DNA damage in cancer cells Gad, H.; Mortusewicz, O.; Rudd, S. G.; Stolz, A.; Amaral, N.; Brautigam, L.; Pudelko, L.; Sanjiv, K.; Kalderen, C.; Jemth, A.-S.; Almlof, I.; Visnes, T.; Schultz, N.; Bostrom, J.; Calderon Montano, J. M.; Hagenkort, A.; Groth, P.; Loseva, O.; Gokturk, C.; Koolmeister, T.; Wakchaure, P.; Homan, E.; Strom, C. E.; Scobie, M.; Bastians, H.; Warpman Berglund, U.; Helleday, T. 10.1101/575290 — cancer biology — Posted on 2019-03-12 2144 Bistability and oscillations in cooperative microtubule and kinetochore dynamics in the mitotic spindle Schwietert, F.; Kierfeld, J. 10.1101/575530 — biophysics — Posted on 2019-03-12 2145 Difference contact maps: from what to why in the analysis of the conformational flexibility of proteins Iyer, M.; Li, Z.; Jaroszewski, L.; Sedova, M.; Godzik, A. 10.1101/575696 — bioinformatics — Posted on 2019-03-12 2146 Association between hot flashes severity and oxidative stress among Mexican postmenopausal women: a cross-sectional study Sanchez-Rodriguez, M. A.; Zacarias-Flores, M.; Arronte-Rosales, A.; Mendoza-Nunez, V. M. 10.1101/575621 — biochemistry — Posted on 2019-03-12 2147 XPO1 gene therapy restores cardiac function in rats with chronic induced myocardial infarction Garcia-Manzanares, M.; Gil-Cayuela, C.; Martinez-Dolz, L.; Gonzalez Juanatey, J. R.; Lago, F.; Portoles, M.; Rosello-Lleti, E.; Rivera, J. M. 10.1101/575340 — molecular biology — Posted on 2019-03-12 2148 WinnerTakeAlmostAll: A parsimony approach integrating multi-targets improves marker gene profiling Song, Z.; Sun, X.; Xia, Z.; Jia, Y.; Zhu, J.; Fang, C.; Yang, H.; Wang, J. 10.1101/575100 — bioinformatics — Posted on 2019-03-12 2149 The fitness cost and benefit of phase separated protein deposits Sanchez de Groot, N.; Torrent Burgas, M.; Ravarani, C. N. J.; Trusina, A.; Ventura, S.; Babu, M. 10.1101/574657 — systems biology — Posted on 2019-03-12 2150 Overexpression of the Rieske FeS protein of the Cytochrome b6f complex increases C4 photosynthesis Ermakova, M.; Lopez-Calcagno, P. E.; Raines, C. A.; Furbank, R. T.; von Caemmerer, S. 10.1101/574897 — plant biology — Posted on 2019-03-12 2151 Conserved residues in the wheat (Triticum aestivum) NAM-A1 NAC domain are required for protein binding and when mutated lead to delayed peduncle and flag leaf senescence Harrington, S. A.; Overend, L. E.; Cobo, N.; Borrill, P.; Uauy, C. 10.1101/573881 — plant biology — Posted on 2019-03-12 2152 The role of strigolactones in regulation of stomatal conductance and plant-pathogen interactions in Arabidopsis thaliana Kalliola, M.; Jakobson, L.; Davidsson, P.; Pennanen, V.; Waszczak, C.; Yarmolinsky, D.; Zamora, O.; Palva, E. T.; Kariola, T.; Kollist, H.; Brosche, M. 10.1101/573873 — plant biology — Posted on 2019-03-12 2153 Capsidiol, a defensive sesquiterpene produced by wild tobacco in response to attack from the fungal pathogen Alternaria alternata, is regulated by an ERF2-like transcription factor Na, S.; Ma, L.; Wang, W.; Sun, H.; Wang, L.; Baldwin, I. T.; Wu, J. 10.1101/573675 — plant biology — Posted on 2019-03-12 2154 Effects of a demand optimization intervention on laboratory test utilization in primary care Bucholc, M.; O'Kane, M.; O'Hare, B.; Mullan, C.; Cavanagh, P.; Ashe, S. 10.1101/573956 — pathology — Posted on 2019-03-12 2155 Root caries on a Paranthropus robustus third molar from Drimolen Towle, I.; Riga, A.; Irish, J. D.; Dori, I.; Menter, C.; Moggi-Cecchi, J. 10.1101/573964 — paleontology — Posted on 2019-03-12 2156 Estimating statistical power for event-related potential studies using the late positive potential Gibney, K. D.; Kypriotakis, G.; Cinciripini, P.; Robinson, J.; Minnix, J.; Versace, F. 10.1101/574368 — neuroscience — Posted on 2019-03-12 2157 Dopamine transients delivered in learning contexts do not act as model-free prediction errors Sharpe, M. J.; Batchelor, H. M.; Mueller, L. E.; Chang, C. Y.; Maes, E. J. P.; Niv, Y.; Schoenbaum, G. 10.1101/574541 — neuroscience — Posted on 2019-03-12 2158 A computational model of intrathalamic signaling via open-loop thalamo-reticular-thalamic architectures Brown, J. W.; Taheri, A.; Kenyon, R. V.; Berger-Wolf, T.; Llano, D. A. 10.1101/574178 — neuroscience — Posted on 2019-03-12 2159 Optimization of the navigated TMS mapping algorithm for accurate detection of plasticity and abnormalities in cortical muscle representations Sinitsyn, D. O.; Chernyavskiy, A. Y.; Poydasheva, A. G.; Bakulin, I. S.; Suponeva, N. A.; Piradov, M. A. 10.1101/573220 — neuroscience — Posted on 2019-03-12 2160 Exploitation of the cooperative behaviours of anti-CRISPR phages Chevallereau, A.; Meaden, S.; Fradet, O.; Landsberger, M.; Maestri, A.; Biswas, A.; Gandon, S.; van Houte, S.; Westra, E. 10.1101/574418 — microbiology — Posted on 2019-03-12 2161 Transcriptome profiling of mouse samples using nanopore sequencing of cDNA and RNA molecules Sessegolo, C.; Cruaud, C.; Da Silva, C.; Dubarry, M.; Derrien, T.; Lacroix, V.; Aury, J.-M. 10.1101/575142 — bioinformatics — Posted on 2019-03-12 2162 Towards accurate high-throughput ligand affinity prediction by exploiting structural ensembles, docking metrics and ligand similarity Schneider, M.; Pons, J.-L.; Bourguet, W.; Labesse, G. 10.1101/574517 — bioinformatics — Posted on 2019-03-12 2163 Anodal transcranial direct current stimulation reduces collinear lateral inhibition in normal peripheral vision Nallour Raveendran, R.; Tsang, K.; Tiwana, D.; Thompson, B. 10.1101/574590 — neuroscience — Posted on 2019-03-12 2164 Forward modelling reveals dynamics of neural orientation tuning to unconscious visual stimuli during binocular rivalry Tang, M. F.; Arabzadeh, E.; Mattingley, J. B. 10.1101/574905 — neuroscience — Posted on 2019-03-12 2165 A failed top-down control from prefrontal cortex to amygdala in generalized anxiety disorder: evidence from resting-state fMRI with Granger causality analysis Dong, M.; Xia, L.; Lu, M.; Li, C.; Xu, K.; Zhang, L. 10.1101/573634 — neuroscience — Posted on 2019-03-12 2166 Structural Basis for the Clamping and Ca2+ Activation of SNARE-mediated Fusion by Synaptotagmin Grushin, K.; Wang, J.; Coleman, J.; Rothman, J. E.; Sindelar, C. E.; Krishnakumar, S. S. 10.1101/574632 — neuroscience — Posted on 2019-03-12 2167 A practical computerized decision support system for predicting the severity of Alzheimer’s disease of an individual Bucholc, M.; Ding, X.; Wang, H.; Glass, D.; Wang, H.; Prasad, G.; Maguire, L.; Bjourson, A.; McClean, P.; Todd, S.; Finn, D.; Wong-Lin, K. 10.1101/573899 — neuroscience — Posted on 2019-03-12 2168 Entrainment of local synchrony reveals a causal role for high-beta right frontal oscillations in human visual consciousness Vernet, M.; Stengel, C.; Quentin, R.; Amengual, J. L.; Valero-Cabre, A. 10.1101/574939 — neuroscience — Posted on 2019-03-12 2169 Colocalization of MOR1 and GAD67 in Mouse Nucleus Accumbens Hinkle, C. F.; Dedkov, E. I.; Buono, R. J.; Ferraro, T. N. 10.1101/574434 — neuroscience — Posted on 2019-03-12 2170 Dilated Saliency U-Net for White Matter Hyperintensities Segmentation using Irregularity Age Map Jeong, Y.; Rachmadi, M. F.; Valdes Hernandez, M. d. C.; Komura, T. 10.1101/550517 — neuroscience — Posted on 2019-03-12 2171 Effects of dietary replacement of broiler litter with Melia azedarach foliage on productive performance, fatty acid composition and health-related fatty acid indices in beef fats from Nguni x Brahman steers fed sugarcane tops based diets Mthiyane, D. M. N.; Dlamini, B. J.; Hugo, A.; Nsahlai, I. V. 10.1101/573667 — molecular biology — Posted on 2019-03-12 2172 The ubiquitin-conjugating enzyme Ubc13-Mms2 cooperates with a family of FYVE-type-RING ubiquitin protein ligases in K63-polyubiquitylation at internal membranes Renz, C.; Troester, V.; Albert, T. K.; Santt, O.; Jacobs, S. C.; Khmelinskii, A.; Ulrich, H. D. 10.1101/575241 — molecular biology — Posted on 2019-03-12 2173 Structure elucidation of colibactin. Xue, M.; Kim, C. S.; Healy, A. R.; Wernke, K. W.; Wang, Z.; Frischling, M. C.; Shine, E. E.; Wang, W.; Herzon, S. B.; Crawford, J. M. 10.1101/574053 — microbiology — Posted on 2019-03-12 2174 Dynamics of Mycobacterium tuberculosis Ag85B revealed by sensitive ELISA Ernst, J.; Cornelius, A.; Bolz, M. 10.1101/574996 — microbiology — Posted on 2019-03-12 2175 Effects of graphene oxide and graphite on soil bacterial and fungal diversity Forstner, C.; Orton, T. G.; Skarshewski, A.; Wang, P.; Kopittke, P. M.; Dennis, P. G. 10.1101/530485 — microbiology — Posted on 2019-03-12 2176 T Cell Receptor Immunotherapy Drives Human Immunodeficiency Virus Evolution in Humanized Mice Joglekar, A. V.; Swift, M.; Leonard, M. T.; Jeppson, J. D.; Sandoval, S.; Baltimore, D. 10.1101/574608 — immunology — Posted on 2019-03-12 2177 Phased genome sequence of an interspecific hybrid flowering cherry, Somei-Yoshino (Cerasus x yedoensis) Shirasawa, K.; Esumi, T.; Hirakawa, H.; Tanaka, H.; Itai, A.; Ghelfi, A.; Nagasaki, H.; Isobe, S. 10.1101/573451 — genomics — Posted on 2019-03-12 2178 Characterisation of l(3)tb as a novel tumour suppressor allele of DCP2 in Drosophila melanogaster Mishra, R.; Kunar, R.; MANDAL, L.; Alone, D. P.; Chandrasekharan, S.; Tiwari, A. K.; Mukherjee, A.; Tapadia, M. G.; Roy, J. K. 10.1101/574707 — genetics — Posted on 2019-03-12 2179 Genetic analysis identifies molecular systems and biological pathways associated with household income Hill, W. D.; Davies, N. M.; Ritchie, S. J.; Skene, N. G.; Bryois, J.; Bell, S.; Di Angelantonio, E.; Roberts, D. J.; Xueyi, S.; Davies, G.; Liewald, D. C. M.; Porteous, D. J.; Hayward, C.; Butterworth, A. S.; McIntosh, A. M.; Gale, C. R.; Deary, I. J. 10.1101/573691 — genetics — Posted on 2019-03-12 2180 Metformin rescues muscle function in BAG3 myofibrillar myopathy models Ruparelia, A. A.; McKaige, E. A.; Williams, C.; Schulze, K. E.; Fuchs, M.; Oorschot, V.; Lacene, E.; Mirella, M.; Baxter, E. C.; TORRENTE, Y.; Ramm, G.; Stojkovic, T.; Lavoie, J. N.; Bryson-Richardson, R. J. 10.1101/574806 — genetics — Posted on 2019-03-12 2181 Mean-field computational approach to HIV dynamics on a fitness landscape Chen, H.; Kardar, M. 10.1101/518704 — evolutionary biology — Posted on 2019-03-12 2182 The bacterial endosymbiont Wolbachia increases reproductive investment and accelerates the life cycle of ant colonies SINGH, R.; Linksvayer, T. A. 10.1101/574921 — evolutionary biology — Posted on 2019-03-12 2183 The structure of species discrimination signals across a primate radiation Winters, S.; Allen, W. L.; Higham, J. P. 10.1101/574558 — evolutionary biology — Posted on 2019-03-12 2184 Phytoplasma SAP11 effector destabilization of TCP transcription factors differentially impact development and defence of Arabidopsis versus maize Pecher, P.; Moro, G.; Canale, M. C.; Capdevielle, S.; Singh, A.; MacLean, A.; Sugio, A.; Kuo, C.-H.; Lopes, J. R. S.; Hogenhout, S. A. 10.1101/574319 — evolutionary biology — Posted on 2019-03-12 2185 Integrating natural history-derived phenomics with comparative genomics to study the genetic architecture of convergent evolution Lamichhaney, S.; Card, D. C.; Grayson, P.; Tonini, J. F.; Bravo, G. A.; Napflin, K.; Garcia, F. T.; Torres, C.; Burbrink, F.; Clark, J. A.; Sackton, T. B.; Edwards, S. V. 10.1101/574756 — evolutionary biology — Posted on 2019-03-12 2186 Investigation of the validity of two Bayesian ancestral state reconstruction models for estimating Salmonella transmission during outbreaks Bloomfield, S.; Vaughan, T.; Benschop, J.; Marshall, J.; Hayman, D.; Biggs, P.; Carter, P.; French, N. 10.1101/574087 — epidemiology — Posted on 2019-03-12 2187 Perceptions, attitudes and practices towards scabies in communities on the Bijagos Islands, Guinea-Bissau Lopes, M. J.; Teixeira da Silva, E.; Ca, J.; Goncalves, A.; Rodrigues, A.; Mandjuba, C.; Nakutum, J.; D'Alessandro, U.; Achan, J.; Logan, J.; Bailey, R.; Walker, S.; Last, A.; Marks, M. 10.1101/574327 — epidemiology — Posted on 2019-03-12 2188 Relation of in-utero exposure to antiepileptic drugs to pregnancy duration and size at birth Margulis, A. V.; Hernandez-Diaz, S.; McElrath, T.; Rothman, K. J.; Plana, E.; Almqvist, C.; D'Onofrio, B. M.; Oberg, A. S. 10.1101/574269 — epidemiology — Posted on 2019-03-12 2189 Best practices for making reliable inferences from citizen science data: case study using eBird to estimate species distributions Johnston, A.; Hochachka, W. M.; Strimas-Mackey, M.; Ruiz Gutierrez, V.; Robinson, O. J.; Miller, E. T.; Auer, T.; Kelling, S. T.; Fink, D. 10.1101/574392 — ecology — Posted on 2019-03-12 2190 Regional climate affects salmon lice population dynamics, stage structure, and management Hurford, A.; Wang, X.; Zhao, X.-Q. 10.1101/574830 — ecology — Posted on 2019-03-12 2191 Disrupting butterfly microbiomes does not affect host survival and development Phalnikar, K.; Kunte, K.; Agashe, D. 10.1101/574871 — ecology — Posted on 2019-03-12 2192 Is microbial activity in tropical forests limited by phosphorus availability? Evidence from a tropical forest in China Mori, T.; Lu, X.; Wang, C.; Mao, Q.; Wang, S.; Zhang, W.; Mo, J. 10.1101/575001 — ecology — Posted on 2019-03-12 2193 Satb2 regulates proliferation and nuclear integrity of pre-osteoblasts Dowrey, T.; Schwager, E. E.; Duong, J.; Merkuri, F.; Zarate, Y. A.; Fish, J. L. 10.1101/574863 — developmental biology — Posted on 2019-03-12 2194 A pivotal genetic program controlled by thyroid hormone during the maturation of GABAergic neurons in mice Richard, S.; Guyot, R.; Rey-Millet, M.; Prieux, M.; Markossian, S.; Aubert, D.; Flamant, F. 10.1101/574202 — developmental biology — Posted on 2019-03-12 2195 A novel, dynein-independent mechanism focuses the endoplasmic reticulum around spindle poles in dividing Drosophila spermatocytes Karabasheva, D.; Smyth, J. T. 10.1101/574855 — cell biology — Posted on 2019-03-12 2196 Chaperone-Mediated Reflux of Secretory Proteins to the Cytosol During Endoplasmic Reticulum Stress Igbaria, A.; Merksamer, P. I.; Trusina, A.; Tilahun, F.; Johnson, J. R.; Brandman, O.; Krogan, N. J.; Weissman, J. S.; Papa, F. R. 10.1101/562306 — cell biology — Posted on 2019-03-12 2197 Size-Dependent Secretory Protein Reflux into the Cytosol in Association with Acute Endoplasmic Reticulum Stress Snapp, E.; Lajoie, P. 10.1101/573428 — cell biology — Posted on 2019-03-12 2198 Cultured pluripotent planarian stem cells retain potency and express proteins from exogenously introduced mRNAs Sanchez Alvarado, A.; Lei, K.; McKinney, S. A.; Ross, E. J.; Lee, H.-C. 10.1101/573725 — cell biology — Posted on 2019-03-12 2199 C3G (RapGEF1) localizes to the mother centriole and regulates centriole division and primary cilia dynamics Nayak, S. C.; Radha, V. 10.1101/575225 — cell biology — Posted on 2019-03-12 2200 Modeling non-genetic dynamics of cancer cell states measured by single-cell analysis: Uncovering bifurcations that explain why treatment either kills a cancer cell or makes it resistant Huang, S. 10.1101/574848 — cancer biology — Posted on 2019-03-12 2201 MTH1 inhibitor TH588 induces mitosis-dependent accumulation of genomic 8-oxodG and disturbs mitotic progression Rudd, S. G.; Gad, H.; Amaral, N.; Hagenkort, A.; Groth, P.; Strom, C. E.; Mortusewicz, O.; Warpman-Berglund, U.; Helleday, T. 10.1101/573931 — cancer biology — Posted on 2019-03-12 2202 Heterogeneous loop model to infer 3D chromosome structures from Hi-C Liu, L.; Kim, M. H.; Hyeon, C. 10.1101/574970 — biophysics — Posted on 2019-03-12 2203 The Use of iPSC-Derived Cardiomyocytes and Optical Mapping for Erythromycin Arrhythmogenicity Testing Podgurskaya, A.; Tsvelaya, V.; Slotvitsky, M.; Dementyeva, E.; Valetdinova, K.; Agladze, K. 10.1101/574012 — biophysics — Posted on 2019-03-12 2204 Multivariate pattern classification on BOLD activation pattern induced by deep brain stimulation in motor, associative, and limbic brain networks Cho, S.; Min, H.-K.; Gibson, W.; In, M.-H.; Lee, K. H.; Jo, H. J. 10.1101/574889 — bioinformatics — Posted on 2019-03-12 2205 Deep Learning of Representations for Transcriptomics-based Phenotype Prediction Smith, A. M.; Walsh, J. R.; Long, J.; Davis, C. B.; Henstock, P.; Hodge, M. R.; Maciejewski, M.; Mu, X. J.; Ra, S.; Zhang, S.; Ziemek, D.; Fisher, C. K. 10.1101/574723 — bioinformatics — Posted on 2019-03-12 2206 conLSH: Context based Locality Sensitive Hashing for Mapping of noisy SMRT Reads Chakraborty, A.; Bandyopadhyay, S. 10.1101/574467 — bioinformatics — Posted on 2019-03-12 2207 PHi-C: deciphering Hi-C data into polymer dynamics Shinkai, S.; Nakagawa, M.; Sugawara, T.; Togashi, Y.; Ochiai, H.; Nakato, R.; Taniguchi, Y.; Onami, S. 10.1101/574962 — bioinformatics — Posted on 2019-03-12 2208 Genome-wide profiling of microRNAs and prediction of mRNA targets in 17 bovine tissues Wang, M.; Chamberlain, A. J.; Prowse-Wilkins, C. P.; Vander Jagt, C. J.; Hancock, T. P.; Pryce, J. E.; Cocks, B. G.; Goddard, M. E.; Hayes, B. J. 10.1101/574954 — bioinformatics — Posted on 2019-03-12 2209 SNP Identity Searching Across Ethnicities, Kinship, and Admixture Helfer, B. S.; Ricke, D. O. 10.1101/574566 — bioinformatics — Posted on 2019-03-12 2210 Computational Inference Software for Tetrad Assembly from Randomly Arrayed Yeast Colonies Sakhanenko, N. A.; Cromie, G.; Dudley, A. M.; Galas, D. J. 10.1101/574376 — bioinformatics — Posted on 2019-03-12 2211 Selective labelling of arginine residues engaged in binding sulfatedglycosaminoglycans Bui, P. T.; li, y.; Sarsby, J.; Nunes, Q.; Wilkinson, M.; Fernig, D. 10.1101/574947 — biochemistry — Posted on 2019-03-12 2212 Primary care use of laboratory tests in Northern Ireland Western Health and Social Care Trust: a cross-sectional study Bucholc, M.; O'Kane, M.; Mullan, C.; Ashe, S.; Maguire, L. 10.1101/573949 — biochemistry — Posted on 2019-03-12 2213 Endothelial PKA targets ATG16L1 to regulate angiogenesis by limiting autophagy Zhao, X.; Nedvetsky, P.; Vion, A.-C.; Popp, O.; Zühlke, K.; Dittmar, G.; Klussmann, E.; Gerhardt, H. 10.1101/573683 — biochemistry — Posted on 2019-03-12 2214 Long-tailed macaques extract statistical information from repeated types of events to make rational decisions under uncertainty Placi, S.; Padberg, M.; Rakoczy, H.; Fischer, J. 10.1101/574475 — animal behavior and cognition — Posted on 2019-03-12 2215 The Life History of Human Foraging: Cross-Cultural and Individual Variation Koster, J.; McElreath, R.; Hill, K.; Yu, D.; Shepard, G.; van Vliet, N.; Gurven, M.; Kaplan, H.; Trumble, B.; Bliege Bird, R.; Bird, D.; Codding, B.; Coad, L.; Pacheco-Cobos, L.; Winterhalder, B.; Lupo, K.; Schmitt, D.; Sillitoe, P.; Franzen, M.; Alvard, M.; Venkataraman, V.; Kraft, T.; Endicott, K.; Beckerman, S.; Marks, S.; Headland, T.; Pangau-Adam, M.; Siren, A.; Kramer, K.; Greaves, R.; Reyes-Garcia, V.; Gueze, M.; Duda, R.; Fernandez-Llamazares, A.; Gallois, S.; Napitupulu, L.; Ellen, R.; Ziker, J.; Nielsen, M.; Ready, E.; Healey, C.; Ross, C. 10.1101/574483 — animal behavior and cognition — Posted on 2019-03-12 2216 Bioelectrical signaling via domain wall migration McNamara, H. M.; Salegame, R.; Al Tanoury, Z.; Xu, H.; Begum, S.; Ortiz, G.; Pourquie, O.; Cohen, A. E. 10.1101/570440 — biophysics — Posted on 2019-03-12 2217 Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis Ashouri, J.; Hsu, L.-Y.; Yu, S.; Rychkov, D.; Chen, Y.; Chang, D.; Sirota, M.; Hansen, E.; Lattanza, L.; Zikherman, J.; Weiss, A. 10.1101/474700 — immunology — Posted on 2019-03-12 2218 Regulation of cerebrospinal fluid and brain tissue sodium levels by choroid plexus and brain capillary endothelial cell sodium-potassium pumps during migraine Ghaffari, H.; Grant, S. C.; Petzold, L. R.; Harrington, M. G. 10.1101/572727 — systems biology — Posted on 2019-03-12 2219 TrkB Activation During a Critical Period Mimics the Protective Effects of Early Visual Experience on Perception and the Stability of Receptive Fields in Adult Superior Colliculus Mudd, D. B.; Balmer, T. S.; Kim, S. Y.; Machhour, N.; Pallas, S. L. 10.1101/435784 — neuroscience — Posted on 2019-03-12 2220 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps Moritz, S.; Pfab, J.; Si, D.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L. 10.1101/572990 — molecular biology — Posted on 2019-03-12 2221 Revealing evolutionary constraints on proteins through sequence analysis Wang, S.-W.; Bitbol, A.-F.; Wingreen, N. S. 10.1101/397521 — biophysics — Posted on 2019-03-12 2222 The protein repertoire in early vertebrate embryogenesis Peshkin, L.; Lukyanov, A.; Kalocsay, M.; Gage, R. M.; Wang, D.; Pells, T. J.; Karimi, K.; Vize, P. D.; Wuhr, M.; Kirschner, M. W. 10.1101/571174 — developmental biology — Posted on 2019-03-11 2223 G1/S transcription factors assemble in discrete clusters that increase in number as cells grow Black, L.; Tollis, S.; Fiche, J.-B.; Dorsey, S.; Cheng, J.; Notley, S.; Crevier, B.; Bigness, J.; Nollmann, M.; Tyers, M.; Royer, C. A. 10.1101/574772 — cell biology — Posted on 2019-03-11 2224 Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels Salehin, M.; Li, B.; Tang, M.; Katz, E.; Song, L.; Ecker, J.; Kliebenstein, D.; Estelle, M. 10.1101/572305 — plant biology — Posted on 2019-03-11 2225 Mitogen-Activated Protein Kinase-Dependent Fiber-Type Regulation in Skeletal Muscle Boyer, J. G.; Song, T.; Lee, D.; Fu, X.; Sadayappan, S.; Molkentin, J. D. 10.1101/361600 — developmental biology — Posted on 2019-03-11 2226 Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium Postema, M. C.; van Rooij, D.; Anagnostou, E.; Arango, C.; Auzias, G.; Behrmann, M.; Filho, G. B.; Calderoni, S.; Calvo, R.; Daly, E.; Deruelle, C.; Di Martino, A.; Dinstein, I.; Duran, F. L. S.; Durston, S.; Ecker, C.; Ehrlich, S.; Fair, D.; Fedor, J.; Feng, X.; Fitzgerald, J.; Floris, D. L.; Freitag, C. M.; Gallagher, L.; Glahn, D. C.; Gori, I.; Haar, S.; Hoekstra, L.; Jahansad, N.; Jalbrzikowski, M.; Janssen, J.; King, J. A.; Zaro, L. L.; Lerch, J. P.; Luna, B.; Martinho, M. M.; McGrath, J.; Medland, S. E.; Muratori, F.; Murphy, C. M.; Murphy, D. G. M.; O'Hearn, K.; Oranje, B.; Parellada, 10.1101/570655 — neuroscience — Posted on 2019-03-11 2227 Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins Tyssowski, K. M.; Gray, J. M. 10.1101/572370 — neuroscience — Posted on 2019-03-11 2228 Simultaneous mesoscopic Ca2+ imaging and fMRI: Neuroimaging spanning spatiotemporal scales Lake, E. M.; Ge, X.; Shen, X.; Herman, P.; Hyder, F.; Cardin, J. A.; Higley, M. J.; Scheinost, D.; Papademetris, X.; Crair, M. C.; Constable, R. T. 10.1101/464305 — neuroscience — Posted on 2019-03-11 2229 Gut microbiome structure and adrenocortical activity in dogs with aggressive and phobic behavioral disorders Mondo, E.; Barone, M.; Soverini, M.; D'Amico, F.; Marliani, G.; Cocchi, M.; Mattioli, M.; Candela, M.; Accorsi, P. A. 10.1101/573865 — microbiology — Posted on 2019-03-11 2230 Transcriptional profiling reveals running promotes cerebrovascular remodeling in young but not aged mice Foley, K. E.; Yang, S.; Graham, L. C.; Howell, G. R. 10.1101/574673 — genomics — Posted on 2019-03-11 2231 Genetic structure is stronger across human-impacted habitats than among islands in the coral Porites lobata Tisthammer, K. H.; Forsman, Z. H.; Toonen, R. J.; Richmond, R. H. 10.1101/574665 — genetics — Posted on 2019-03-11 2232 Cross-disorder genetic analyses implicate dopaminergic signaling as a biological link between Attention-Deficit/Hyperactivity Disorder and obesity measures Mota, N. R.; Poelmans, G.; Klein, M.; Torrico, B.; Fernandez-Castillo, N.; Cormand, B.; Reif, A.; Franke, B.; Arias-Vasquez, A. 10.1101/573808 — genetics — Posted on 2019-03-11 2233 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs Marchant, A.; Cisneros, A.; Dube, A. K.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C. R. 10.1101/564401 — evolutionary biology — Posted on 2019-03-11 2234 Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria Ajogbasile, F. V.; Oguzie, J. U.; Oluniyi, P. E.; Eromon, P.; Uwanibe, J.; Mehta, S. B.; Siddle, K. J.; Odia, I.; Winnicki, S. M.; Akpede, N.; Akpede, G.; Okogbenin, S.; MacInnis, B. L.; Folarin, O. A.; Schaffner, S. F.; Ogbaini-Emovon, E.; Tomori, O.; Ihekweazu, C.; Sabeti, P. C.; Happi, C. T. 10.1101/572354 — genomics — Posted on 2019-03-11 2235 Interpretable classification of Alzheimer’s disease pathologies with a convolutional neural network pipeline Tang, Z.; Chuang, K. V.; DeCarli, C.; Jin, L.-W.; Beckett, L.; Keiser, M. J.; Dugger, B. N. 10.1101/454793 — pathology — Posted on 2019-03-11 2236 The Neural Basis of Shared Preference Learning Farmer, H.; Hamilton, A.; Hertz, U. 10.1101/570762 — neuroscience — Posted on 2019-03-11 2237 Short translational ramp determines efficiency of protein synthesis Verma, M.; Choi, J.; Cottrell, K. A.; Lavagnino, Z.; Thomas, E. N.; Pavlovic Djuranovic, S.; Szczesny, P.; Piston, D. W.; Zaher, H.; Puglisi, J. D.; Djuranovic, S. 10.1101/571059 — molecular biology — Posted on 2019-03-11 2238 A comprehensive atlas of immunological differences between humans, mice and non-human primates Bjornson, Z.; Fragiadakis, G. K.; Spitzer, M. H.; Madhireddy, D.; McIlwain, D.; Nolan, G. P. 10.1101/574160 — immunology — Posted on 2019-03-11 2239 The genome of Drosophila innubila reveals lineage-specific patterns of selection in immune genes Hill, T.; Koseva, B.; Unckless, R. L. 10.1101/383877 — genomics — Posted on 2019-03-11 2240 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J. 10.1101/574426 — genetics — Posted on 2019-03-11 2241 Karyotypic divergence confounds cellular phenotypes in large pharmacogenomic studies Quevedo, R.; El-Hachem, N.; Smirnov, P.; Safikhani, Z.; Pugh, T. J.; Haibe-Kains, B. 10.1101/574350 — cancer biology — Posted on 2019-03-11 2242 Scalable methods for analyzing and visualizing phylogenetic placement of metagenomic samples Czech, L.; Stamatakis, A. 10.1101/346353 — bioinformatics — Posted on 2019-03-11 2243 MoMI-G: Modular Multi-scale Integrated Genome Graph Browser Yokoyama, T. T.; Sakamoto, Y.; Seki, M.; Suzuki, Y.; Kasahara, M. 10.1101/540120 — bioinformatics — Posted on 2019-03-11 2244 Inhibition of nucleotide synthesis mediates replicative senescence of human mammary epithelial cells Delfarah, A.; Parrish, S.; Junge, J. A.; Yang, J.; Seo, F.; Li, S.; Wang, P.; Fraser, S. E.; Graham, N. 10.1101/423665 — systems biology — Posted on 2019-03-11 2245 A geometric attractor mechanism for self-organization of entorhinal grid modules Kang, L.; Balasubramanian, V. 10.1101/338087 — neuroscience — Posted on 2019-03-11 2246 The influence of kinesthetic motor imagery and effector specificity on the long-latency stretch response Forgaard, C.; Franks, I. M.; Maslovat, D.; Chua, R. 10.1101/510271 — neuroscience — Posted on 2019-03-11 2247 Evaluation of Enhanced Learning Techniques for Segmenting Ischaemic Stroke Lesions in Brain Magnetic Resonance Perfusion Images using a Convolutional Neural Network Scheme Malla, C. U. P.; Valdes Hernandez, M. d. C.; Rachmadi, M. F.; Komura, T. 10.1101/544858 — neuroscience — Posted on 2019-03-11 2248 Revealing metabolic flexibility of Candidatus Accumulibacter phosphatis through redox cofactor analysis and metabolic network modeling Guedes da Silva, L.; Olavarria Gamez, K.; Castro Gomes, J.; Akkermans, K.; Welles, L.; Abbas, B.; van Loosdrecht, M. C. M.; Wahl, S. A. 10.1101/458331 — microbiology — Posted on 2019-03-11 2249 Leishmania major degrades murine CXCL1 - an immune evasion strategy Yorek, M. S.; Poudel, B.; Mazgaeen, L.; Pope, R. M.; Wilson, M. E.; Gurung, P. 10.1101/571141 — microbiology — Posted on 2019-03-11 2250 Feature Selection and Dimension Reduction for Single Cell RNA-Seq based on a Multinomial Model Townes, F. W.; Hicks, S. C.; Aryee, M. J.; Irizarry, R. A. 10.1101/574574 — genomics — Posted on 2019-03-11 2251 Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia Tam, O.; Rozhkov, N. V.; Shaw, R.; Kim, D.; Hubbard, I.; Fennessey, S.; Propp, N.; The NYGC ALS Consortium, ; Fagegaltier, D.; Ostrow, L. W.; Phatnani, H.; Ravits, J.; Dubnau, J.; Gale Hammell, M. 10.1101/574509 — genomics — Posted on 2019-03-11 2252 The transferability of lipid loci across African, Asian and European cohorts Telkar, N.; Reiker, T.; Walters, R. G.; Lin, K.; Eriksson, A.; Gurdasani, D.; Gilly, A.; Southam, L.; Tsafantakis, E.; Karaleftheri, M.; Seeley, J.; Kamali, A.; Asiki, G.; Millwood, I. Y.; Holmes, M.; Du, H.; Guo, Y.; Understanding Society Scientific Group, ; Kumari, M.; Dedoussis, G.; Li, L.; Chen, Z.; Sandhu, M.; Zeggini, E.; Kuchenbaecker, K. 10.1101/525170 — genetics — Posted on 2019-03-11 2253 TIGAR: An Improved Bayesian Tool for Transcriptomic Data Imputation Enhances Gene Mapping of Complex Traits Nagpal, S.; Meng, X.; Epstein, M. P.; Tsoi, L. C.; Patrick, M.; Gibson, G.; De Jager, P.; Bennett, D. A.; Wingo, A. P.; Wingo, T. S.; Yang, J. 10.1101/507525 — genetics — Posted on 2019-03-11 2254 Combination image flow cytometry for single-cell analysis reveals novel methods for isolating subsets of megakaryocyte progenitor populations Bush, L. M.; Healy, C. P.; Marvin, J. E.; Deans, T. L. 10.1101/512442 — cell biology — Posted on 2019-03-11 2255 Identifying chemogenetic interactions from CRISPR knockout screens with drugZ Colic, M.; Wang, G.; Zimmermann, M.; Mascall, K.; McLaughlin, M.; Bertolet, L.; Lenoir, W. F.; Moffat, J.; Angers, S.; Durocher, D.; Hart, T. 10.1101/232736 — bioinformatics — Posted on 2019-03-11 2256 A comprehensive examination of Nanopore native RNA sequencing for characterization of complex transcriptomes Soneson, C.; Yao, Y.; Bratus-Neuenschwander, A.; Patrignani, A.; Robinson, M. D.; Hussain, S. 10.1101/574525 — bioinformatics — Posted on 2019-03-11 2257 Alzheimer disease and Apolipoprotein E4: meningeal brain lymphatics point to new clues in pathogenesis Chrousos, G. P.; Mentis, A. 10.1101/571729 — neuroscience — Posted on 2019-03-11 2258 The invasion of de-differentiating cancer cells into hierarchical tissues Zhou, D.; Luo, Y.; Dingli, D.; Traulsen, A. 10.1101/574251 — evolutionary biology — Posted on 2019-03-11 2259 The TLR5 agonist flagellin modifies phenotypical and enhances functional activation of lung mucosal antigen presenting cells in neonatal mice Sharma, P.; Levy, O.; Dowling, D. J. 10.1101/564054 — immunology — Posted on 2019-03-11 2260 De-novo variants in XIRP1 associated with polydactyly and polysyndactyly in Holstein cattle Braun, M.; Hellige, M.; Gerhauser, I.; Ciurkiewicz, M.; Lehmbecker, A.; Beineke, A.; Baumgaertner, W.; Metzger, J.; Distl, O. 10.1101/574061 — genetics — Posted on 2019-03-11 2261 Single cell expression variability in highly homogeneous populations of human cells is widespread, heritable, and implies cell function Osorio, D.; Yu, X.; Zhong, Y.; Li, G.; Yu, P.; Serpedin, E.; Huang, J.; Cai, J. J. 10.1101/574426 — genetics — Posted on 2019-03-11 2262 Sequential compression across latent space dimensions enhances gene expression signatures Way, G. P.; Zietz, M.; Himmelstein, D. S.; Greene, C. S. 10.1101/573782 — bioinformatics — Posted on 2019-03-11 2263 Learning-accelerated Discovery of Immune-Tumour Interactions Ozik, J.; Collier, N.; Heiland, R.; Macklin, P. 10.1101/573972 — systems biology — Posted on 2019-03-11 2264 Low temperature triggers genome-wide hypermethylation of transposable elements and centromeres in maize ACHOUR, Z.; JOETS, J.; LEGUILLOUX, M.; SELLIER, H.; PICHON, J.-P.; LEVEUGLE, M.; DUBORJAL, H.; CAIUS, J.; BRUNAUD, V.; PAYSANT-LE ROUX, C.; MARY-HUARD, T.; GIAUFFRET, C.; VITTE, C. 10.1101/573915 — plant biology — Posted on 2019-03-11 2265 Cingulate Cortex Atrophy is Associated with Hearing Loss in Presbycusis with Cochlear Amplifier Dysfunction Belkhiria, C.; Vergara, R. C.; San Martin, S.; Leiva, A.; Marcenaro, B.; Martinez, M.; Delgado, C.; Delano, P. H. 10.1101/574228 — neuroscience — Posted on 2019-03-11 2266 Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa Rhoades, N.; Cecere, G.; Hammond, T.; Gladyshev, E. 10.1101/573907 — molecular biology — Posted on 2019-03-11 2267 Mediator subunit MDT-15/MED15 and Nuclear Receptor HIZR-1/HNF4 cooperate to regulate toxic metal stress responses in Caenorhabditis elegans Shomer, N.; Kadhim, A. Z.; Grants, J. M.; Cheng, X.; Poon, A. F.-Y.; Lee, M. Y. Y.; Bhanshali, F.; Muhuri, A.; Park, J. I.; Lee, D.; Lee, S.-J. V.; Lynn, F. C.; Taubert, S. 10.1101/565739 — genetics — Posted on 2019-03-11 2268 MicroRNA Overexpression screen reveals a noncanonical role of CDK2 in regulating neutrophil migration Hsu, A. Y.; Wang, D.; Liu, S.; Lu, J.; Sobreira, R. S.; Bennin, D. A.; Huttenlocher, A.; Wan, J.; Deng, Q. 10.1101/574335 — immunology — Posted on 2019-03-11 2269 Molecular and anatomical organization of the dorsal raphe nucleus Huang, K. W.; Ochandarena, N. E.; Philson, A. C.; Hyun, M.; Birnbaum, J. E.; Cicconet, M.; Sabatini, B. L. 10.1101/573923 — neuroscience — Posted on 2019-03-11 2270 iEDGE: integration of Epi-DNA and Gene Expression and applications to the discovery of somatic copy number-associated drivers in cancer Li, A.; Chapuy, B.; Varelas, X.; Sebastiani, P.; Monti, S. 10.1101/573824 — bioinformatics — Posted on 2019-03-11 2271 Identification of metabolites from tandem mass spectra with a machine learning approach utilizing structural features Li, Y.; Kuhn, M.; Gavin, A.-C.; Bork, P. 10.1101/573790 — bioinformatics — Posted on 2019-03-11 2272 Immediate and deferred epigenomic signature of neuronal activation Fernandez-Albert, J.; Lipinski, M.; Lopez-Cascales, M. T.; Rowley, M. J.; Martin-Gonzalez, A. M.; del Blanco, B.; Corces, V.; Barco, A. 10.1101/534115 — neuroscience — Posted on 2019-03-11 2273 Dissection of acute stimulus-inducible nucleosome remodeling in mammalian cells Comoglio, F.; Simonatto, M.; Polletti, S.; Liu, X.; Smale, S. T.; Barozzi, I.; Natoli, G. 10.1101/573832 — genomics — Posted on 2019-03-11 2274 Proteome of the secondary plastid of Euglena gracilis reveals metabolic quirks and colourful history Novak Vanclova, A. M.; Zoltner, M.; Kelly, S.; Soukal, P.; Zahonova, K.; Füssy, Z.; Ebenezer, T. E.; Lacova Dobakova, E.; Elias, M.; Lukes, J.; Field, M. C.; Hampl, V. 10.1101/573709 — evolutionary biology — Posted on 2019-03-11 2275 Developmental transcriptomes of the sea star, Patiria miniata, illuminate the relationship between conservation of gene expression and morphological conservation Gildor, T.; Cary, G.; Lalzar, M.; Hinman, V.; Ben-Tabou de-Leon, S. 10.1101/573741 — evolutionary biology — Posted on 2019-03-11 2276 ComplexBrowser: a tool for identification and quantification of protein complexes in large scale proteomics datasets Michalak, W.; Tsiamis, V.; Schwammle, V.; Rogowska-Wrzesinska, A. 10.1101/573774 — bioinformatics — Posted on 2019-03-11 2277 An equilibrium binding model for CpG DNA-dependent dimerization of Toll-like receptor 9 Reikine, S.; McLaughlin, S. H.; Johnson, C. M.; Modis, Y. 10.1101/573238 — biochemistry — Posted on 2019-03-11 2278 PRDM16 establishes lineage-specific transcriptional program to promote temporal progression of neural progenitors in the mouse neocortex He, L.; Jones, J.; He, W.; Bjork, B.; Wen, J.; Dai, Q. 10.1101/573857 — developmental biology — Posted on 2019-03-11 2279 Motor context coordinates visually guided walking in Drosophila Cruz, T. L.; Fujiwara, T. E.; Varela, N.; Mohammad, F.; Claridge-Chang, A.; Chiappe, M. E. 10.1101/572792 — neuroscience — Posted on 2019-03-11 2280 Sensitivity of Olfactory Sensory Neurons to food cues is tuned to nutritional states by Neuropeptide Y signalling Kaniganti, T.; Deopgade, A.; Maduskar, A.; Mukherjee, A.; Guru, A.; Subhedar, N.; Ghose, A. 10.1101/573170 — neuroscience — Posted on 2019-03-11 2281 Metabolic constraints drive self-organization of specialized cell groups Varahan, S.; Walvekar, A.; Sinha, V.; Krishna, S.; Laxman, S. 10.1101/573626 — cell biology — Posted on 2019-03-11 2282 Differential modulation of mouse heart gene expression by infection with two Trypanosoma cruzi strains: a transcriptome analysis Rezende de Castro, T. B.; Campos Canesso, M. C.; Boroni, M.; Chame, D. F.; de Laet Souza, D.; Toledo, N. E.; Tahara, E. B.; Pena, S. D.; Machado, C. R.; Chiari, E.; Macedo, A. M.; Franco, G. R. 10.1101/574343 — bioinformatics — Posted on 2019-03-11 2283 A mathematical model of Campylobacter dynamics within a broiler flock Rawson, T.; Stamp Dawkins, M.; Bonsall, M. 10.1101/574301 — systems biology — Posted on 2019-03-11 2284 Development of a model estimating root length density from root impacts on a soil profile in pearl millet (Pennisetum glaucum (L.) R. Br). Application to measure root system response to water stress in field conditions Faye, A.; Sine, B.; Chopart, J.-L.; Grondin, A.; Lucas, M.; Diedhiou, A. G.; Gantet, P.; Cournac, L.; Min, D.; Audebert, A.; Kane, A.; Laplaze, L. 10.1101/574285 — plant biology — Posted on 2019-03-11 2285 Multimorbidity and healthcare utilization: A register-based study in Denmark Frolich, A.; Ghith, N.; Schiotz, M.; Jacobsen, R.; Stockmarr, A. 10.1101/574293 — epidemiology — Posted on 2019-03-11 2286 Quadriceps and hamstrings coactivation in exercises used in prevention and rehabilitation of hamstring strain injury in young soccer players Torres, G.; Chorro, D.; Navandar, A.; Rueda, J.; Fernandez, L.; Navarro, E. 10.1101/574210 — scientific communication and education — Posted on 2019-03-11 2287 Regional brain development analysis through registration using anisotropic similarity, a constrained affine transformation Legouhy, A.; Commowick, O.; Proisy, M.; Rousseau, F.; Barillot, C. 10.1101/574129 — neuroscience — Posted on 2019-03-11 2288 In vitro evaluation of probiotic properties of lactic acid bacteria isolated from some traditionally fermented Ethiopian food products Weldesiet, G. M. M.; Tesfaye, A.; Muleta, D.; Tessema, T. S. 10.1101/574194 — microbiology — Posted on 2019-03-11 2289 Procaine and S-adenosyl-L-homocysteine (SAH) affect the expression of genes related to the epigenetic machinery and change the DNA methylation status of in vitro cultured bovine skin fibroblasts Schumann, N. A. B.; Mendonca, A. d. S.; Silveira, M. M.; Vargas, L. N.; Leme, L. O.; Sousa, R. V. d.; Franco, M. M. 10.1101/574186 — genetics — Posted on 2019-03-11 2290 A high-density genetic map and molecular sex-typing assay for gerbils Brekke, T. D.; Supriya, S.; Denver, M.; Thom, A.; Steele, K. A.; Mulley, J. F. 10.1101/567016 — genetics — Posted on 2019-03-11 2291 Diet composition of introduced Barn Owls (Tyto alba javanica) in urban area in comparison with agriculture settings Saufi, S.; Ravindran, S.; Hamid, N. H.; Zainal Abidin, C. M. R.; Ahmad, H.; Ahmad, A. H.; Salim, H. 10.1101/574277 — ecology — Posted on 2019-03-11 2292 A systematic review of MERS-CoV (Middle East Respiratory Syndrome Coronavirus) seroprevalence and viral RNA prevalence in dromedary camels: implications for animal vaccination Dighe, A.; Jombart, T.; Van Kerkhove, M. D.; Ferguson, N. 10.1101/574103 — epidemiology — Posted on 2019-03-11 2293 Injection practices in 2011-2015: A rapid review using data from the Demographic and Health Surveys (DHS) Hayashi, T.; Hutin, Y. J.-F.; Altaf, A.; Allegranzi, B.; Kaneko, S.; Bulterys, M. 10.1101/574137 — epidemiology — Posted on 2019-03-11 2294 Trait plasticity of intensive pasture species due to growth in mixture across seasons and nutrient addition levels Mason, N. W. H.; Orwin, K.; Mudge, P.; Lambie, S.; Waugh, D.; Carmona, C. P. 10.1101/574145 — ecology — Posted on 2019-03-11 2295 Medication-related osteonecrosis of the jaws after tooth extraction in senescent female mice treated with zoledronic acid: microtomographic, histological and immunohistochemical characterization Biguetti, C. C.; De Oliva, A. H.; Healy, K.; Mahmoud, R. H.; Custodio, I. D. C.; Constantino, D. H.; Ervolino, E.; Duarte, M. A. H.; Fakhouri, W. D.; Matsumoto, M. A. 10.1101/574111 — immunology — Posted on 2019-03-11 2296 Frequent sugar feeding behavior by Aedes aegypti in Bamako, Mali makes them ideal candidates for control with attractive toxic sugar baits (ATSB) Sisoko, F.; Junnila, A.; Traore, M.; Traore, S. F.; Doumbia, S.; Dembele, S. M.; Schlein, Y.; Gergely, P.; Xue, R.-d.; Arheart, K. L.; Revay, E. E.; Kravchenko, V. D.; Beier, J. C.; Muller, G. C. 10.1101/574095 — ecology — Posted on 2019-03-11 2297 From root to tips: sporulation evolution and specialization in Bacillus subtilis and the intestinal pathogen Clostridioides difficile Ramos-Silva, P.; Serrano, M.; Henriques, A. O. 10.1101/473793 — evolutionary biology — Posted on 2019-03-11 2298 Real-time contextual feedback for close-loop control of navigation Lim, J.; Celikel, T. 10.1101/473108 — neuroscience — Posted on 2019-03-11 2299 Cerebellar contribution to preparatory activity in motor neocortex Chabrol, F. P.; Blot, A.; Mrsic-Flogel, T. D. 10.1101/335703 — neuroscience — Posted on 2019-03-11 2300 Sen1 is required for RNA Polymerase III transcription termination in an R-loop independent manner. Rivosecchi, J.; Larochelle, M.; Teste, C.; Grenier, F.; Malapert, A.; Ricci, E. P.; Bernard, P.; Bachand, F.; Vanoosthuyse, V. 10.1101/571737 — molecular biology — Posted on 2019-03-11 2301 A pressure sensing protein kinase Akella, R.; Sekulski, K.; Pleinis, J. M.; Liwocha, J.; Jiou, J.; He, H.; Humphreys, J. M.; Schellinger, J. N.; Hu, J.; Cobb, M. H.; Joachimiak, L.; Rodan, A. R.; Goldsmith, E. J. 10.1101/435008 — biophysics — Posted on 2019-03-11 2302 Transcriptomic and Cellular Decoding of Regional Brain Vulnerability to Neurodevelopmental Disorders Seidlitz, J.; Nadig, A.; Liu, S.; Bethlehem, R. A. I.; Vertes, P. E.; Morgan, S. E.; Vasa, F.; Romero-Garcia, R.; Lalonde, F. M.; Clasen, L. S.; Blumenthal, J. D.; Paquola, C.; Bernhardt, B.; Wagstyl, K.; Polioudakis, D.; de la Torre-Ubieta, L.; Geschwind, D. H.; Han, J. C.; Lee, N. R.; Murphy, D. G.; Bullmore, E. T.; Raznahan, A. 10.1101/573279 — neuroscience — Posted on 2019-03-11 2303 Evaluation of extraction solvents for untargeted metabolomics analysis of enrichment reactor cultures performing enhanced biological phosphorus removal (EBPR) Saw, N. M. M. T.; Suwanchaikasem, P.; Zuniga-Montanez, R. E.; Qiu, G.; Wuertz, S.; Williams, R. B. 10.1101/573535 — systems biology — Posted on 2019-03-11 2304 Intracranial functional haemodynamic relationships in patients with cerebral small vessel disease Blair, G. W.; Thrippleton, M. J.; Shi, Y.; Hamilton, I.; Stringer, M.; Chappell, F. M.; Dickie, D. A.; Andrews, P. J.; Marshall, I.; Doubal, F. N.; Wardlaw, J. M. 10.1101/572818 — neuroscience — Posted on 2019-03-11 2305 Modularity in the microcircuitry of the mouse inferior colliculus yields dual processing streams for auditory and multisensory information Lesicko, A. M. H.; Llano, D. A. 10.1101/572776 — neuroscience — Posted on 2019-03-11 2306 Toxoplasma controls host cyclin E expression through the use of a novel MYR1-dependent effector protein, HCE1 Panas, M. W.; Naor, A.; Cygan, A.; Boothroyd, J. 10.1101/573618 — microbiology — Posted on 2019-03-11 2307 Evolutionary patterns of the chimerical retrogenes in Oryza Zhou, Y.; Song, H.; Xiao, J.; Zhang, Q.; Long, M.; Zhang, C. 10.1101/573501 — evolutionary biology — Posted on 2019-03-11 2308 Spreading of molecular mechanical perturbations on linear filaments Balassy, Z.; Lauzon, A.-M.; Hilbert, L. 10.1101/573261 — biophysics — Posted on 2019-03-11 2309 Deriving Accurate Lipid Classification based on Molecular Formula Mitchell, J. M.; Moseley, H. N. B. 10.1101/572883 — systems biology — Posted on 2019-03-11 2310 Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug. Sanderson, L.; da Silva, M.; Sekhar, G. N.; Brown, R. C.; Burrell-Saward, H.; Fidanboylu, M.; Valero, M.; Dreiss, C. A.; Lorenz, C.; Christie, M.; Persaud, S.; Yardley, V.; Croft, S. L.; Thomas, S. A. 10.1101/573329 — pharmacology and toxicology — Posted on 2019-03-11 2311 A response to Zhang et al. (2018), \"Can Mouse-tracking Reveal Attribute Processing Speeds in Dietary Self-control? Commentary on Sullivan et al. (2015) and Lim et al. (2018)\" Sullivan, N. J.; Hutcherson, C.; Harris, A. M.; Rangel, A. 10.1101/572974 — neuroscience — Posted on 2019-03-11 2312 Numerical simulations of different models describing cerebrospinal fluid dynamics Romagnoli, L. 10.1101/573345 — neuroscience — Posted on 2019-03-11 2313 COI metabarcoding primer choice affects richness and recovery of indicator taxa in freshwater systems Hajibabaei, M.; Porter, T. M.; Wright, M.; Rudar, J. 10.1101/572628 — genomics — Posted on 2019-03-11 2314 The importance of being cross-linked for the bacterial cell wall Rani, G.; Patri, I. 10.1101/573113 — biophysics — Posted on 2019-03-11 2315 Intense Pulsed Electric Fields Denature Urease Protein Urabe, G.; Katagiri, T.; Katsuki, S. 10.1101/572784 — biophysics — Posted on 2019-03-11 2316 Identification of DNA motifs that regulate DNA methylation Wang, M.; Zhang, K.; Ngo, V.; Liu, C.; Fan, S.; Whitaker, J. W.; Chen, Y.; Ai, R.; Chen, Z.; Wang, J.; Zheng, L.; Wang, W. 10.1101/573352 — bioinformatics — Posted on 2019-03-11 2317 USVSEG: A robust segmentation of rodents’ ultrasonic vocalization Tachibana, R. O.; Kanno, K.; Okabe, S.; Kobayasi, K. I.; Okanoya, K. 10.1101/572743 — animal behavior and cognition — Posted on 2019-03-11 2318 Visual awareness judgments are sensitive to the outcome of performance monitoring Siedlecka, M.; Wereszczynski, M.; Paulewicz, B.; Wierzchon, M. 10.1101/572503 — animal behavior and cognition — Posted on 2019-03-11 2319 Regulation of cerebrospinal fluid and brain tissue sodium levels by choroid plexus and brain capillary endothelial cell Na+, K+-ATPases during migraine Ghaffari, H.; Grant, S. C.; Petzold, L. R.; Harrington, M. G. 10.1101/572727 — systems biology — Posted on 2019-03-11 2320 Synergetic effect of non-complementary 5’ AT-rich sequences on the development of a multiplex TaqMan real-time PCR for specific and robust detection of Clavibacter michiganensis and C. michiganensis subsp. nebraskensis Larrea-Sarmiento, A.; Alvarez, A. M.; Stack, J. P.; Arif, M. 10.1101/566281 — plant biology — Posted on 2019-03-11 2321 A coevolved EDS1-SAG101-NRG1 module mediates cell death signaling by TIR-domain immune receptors Lapin, D.; Kovacova, V.; Sun, X.; Dongus, J. A.; Bhandari, D. D.; von Born, P.; Bautor, J.; Guarneri, N.; Stuttmann, J.; Beyer, A.; Parker, J. E. 10.1101/572826 — plant biology — Posted on 2019-03-11 2322 Weed regulation by crop and grassland competition: critical biomass level and persistence rate Schuster, M. Z.; Gastal, F.; Doisy, D.; Charrier, X.; de Moraes, A.; Mediene, S.; Barbu, C. M. 10.1101/572701 — plant biology — Posted on 2019-03-11 2323 Convergent gene loss in aquatic plants predicts new components of plant immunity and drought response Baggs, E. L.; Thanki, A. S.; O'Grady, R.; Schudoma, C.; Haerty, W.; Krasileva, K. V. 10.1101/572560 — plant biology — Posted on 2019-03-11 2324 Affordable and robust phenotyping framework to analyse root system architecture of soil-grown plants Bontpart, T.; Concha, C.; Giuffrida, M. V.; Robertson, I.; Admkie, K.; Abdi, T. D.; Wordofa, N. G.; Tesfaye, K.; Teklu, T. H.; Woldemedhin, A. F.; Fetene, M.; Tsaftaris, S.; Doerner, P. 10.1101/573139 — plant biology — Posted on 2019-03-11 2325 Comprehensive Classification of the RNaseH-like domain-containing Proteins in Plants Li, S.; Liu, K.; Sun, Q. 10.1101/572842 — plant biology — Posted on 2019-03-11 2326 Biomarkers for capturing disease pathology as molecular process hyperstructure Lukas, A.; Heinzel, A.; Mayer, B. 10.1101/573402 — pathology — Posted on 2019-03-11 2327 Cortical surface architecture endophenotype and correlates of clinical diagnosis of autism spectrum disorder Yamagata, B.; Itahashi, T.; Fujino, J.; Ohta, H.; Takashio, O.; Nakamura, M.; Kato, N.; Mimura, M.; Hashimoto, R.-i.; Aoki, Y. 10.1101/573527 — neuroscience — Posted on 2019-03-11 2328 Neural basis of approximate number system develops independent of visual experience Kanjlia, S.; Feigenson, L.; Bedny, M. 10.1101/573436 — neuroscience — Posted on 2019-03-11 2329 Neuropeptide B mediates female sexual receptivity in medaka fish, acting in a female-specific but reversible manner Hiraki-Kajiyama, T.; Yamashita, J.; Yokoyama, K.; Hosono, K.; Kawabata-Sakata, Y.; Kikuchi, Y.; Miyazoe, D.; Ansai, S.; Kinoshita, M.; Nagahama, Y.; Okubo, K. 10.1101/573212 — neuroscience — Posted on 2019-03-11 2330 Quantitative Analysis of Trans-synaptic Protein Alignment Chen, J.-H.; Blanpied, T. A.; Tang, A.-H. 10.1101/573063 — neuroscience — Posted on 2019-03-11 2331 Massively Parallel Microwire Arrays Integrated with CMOS chips for Neural Recording Obaid, A. M.; Hanna, M.-E. S.; Wu, Y.-W.; Kollo, M.; Racz, R. R.; Angle, M. R.; Muller, J.; Brackbill, N.; Wray, W.; Franke, F.; Chichilnisky, E. J.; Hierlemann, A.; Ding, J. B.; Schaefer, A. T.; Melosh, N. A. 10.1101/573295 — neuroscience — Posted on 2019-03-11 2332 Send-receive communication asymmetry in brain networks: Inferring directionality of neural signalling from undirected structural connectomes Seguin, C.; Razi, A.; Zalesky, A. 10.1101/573071 — neuroscience — Posted on 2019-03-11 2333 Effects of a rifampicin pre-treatment on linezolid pharmacokinetics Oakazaki, F.; Tsuji, Y.; Seto, Y.; Ogami, C.; Yamamoto, Y.; To, H. 10.1101/572610 — molecular biology — Posted on 2019-03-11 2334 Genome-wide sequencing uncovers cryptic diversity and mito-nuclear discordance in the Octopus vulgaris species complex Amor, M. D.; Doyle, S. R.; Norman, M. D.; Roura, A.; Hall, N. E.; Robinson, A. J.; Leite, T. S.; Strugnell, J. M. 10.1101/573493 — molecular biology — Posted on 2019-03-11 2335 Clades of huge phage from across Earth’s ecosystems Al-Shayeb, B.; Sachdeva, R.; Chen, L.-X.; Ward, F.; Munk, P.; Devoto, A.; Castelle, C. J.; Olm, M. R.; Bouma-Gregson, K.; Amano, Y.; He, C.; Meheust, R.; Brooks, B.; Thomas, A.; Lavy, A.; Matheus-Carnevali, P.; Sun, C.; Goltsman, D.; Borton, M. A.; Nelson, T. C.; Kantor, R.; Jaffe, A. L.; Keren, R.; Farag, I. F.; Lei, S.; Finstad, K.; Amundson, R.; Anantharaman, K.; Zhou, J.; Probst, A. J.; Power, M. E.; Tringe, S. G.; Li, W.-J.; Wrighton, K.; Harrison, S.; Morowitz, M.; Relman, D. A.; Doudna, J. A.; Lehours, A.-C.; Warren, L.; Cate, J. H.; Santini, J. M.; Banfield, J. F. 10.1101/572362 — microbiology — Posted on 2019-03-11 2336 CUX1 and IκBζ mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts Slowikowski, K.; Nguyen, H. N.; Noss, E. H.; Simmons, D. P.; Mizoguchi, F.; Watts, G. F.; Gurish, M. F.; Brenner, M. B.; Raychaudhuri, S. 10.1101/571315 — immunology — Posted on 2019-03-11 2337 Optimized Mucosal MVA Prime/ Soluble gp120 Boost Vaccination Regimen Induces Similar Antibody Responses as an Intramuscular Regimen Jones, D. I.; Pollara, J. J.; Johnson-Weaver, B. T.; LaBranchi, C. C.; Montifiori, D. C.; Pickup, D. J.; Permar, S. R.; Abraham, S. N.; Maddaloni, M.; Pascual, D. W.; Staats, H. F. 10.1101/573394 — immunology — Posted on 2019-03-11 2338 Secondary ossification centers evolved to make endochondral bone growth possible under the weight-bearing demands of a terrestrial environment Xie, M.; Goldin, P.; Herdina, A. N.; Estefa, J.; Medvedeva, E.; Li, L.; Newton, P.; Kotova, S.; Shavkuta, B.; Saxena, A.; Shumate, L.; Metscher, B.; Groschmidt, K.; Nishimori, S.; Akovantseva, A.; Arregui, I. L.; Tafforeau, P.; Fried, K.; Carlstrom, M.; Simon, A.; Gasser, C.; Kronenberg, H.; Bastepe, M.; Cooper, K.; Timashev, P.; Sanchez, S.; Adameyko, I.; Eriksson, A.; Chagin, A. S. 10.1101/571612 — evolutionary biology — Posted on 2019-03-11 2339 Universal trends of post-duplication evolution revealed by the genomes of 13 Paramecium species sharing an ancestral whole-genome duplication. Gout, J.-F.; Johri, P.; Arnaiz, O.; Doak, T. G.; Bhullar, S.; Couloux, A.; Guerin, F.; Malinsky, S.; Sperling, L.; Labadie, K.; Meyer, E.; Duharcourt, S.; Lynch, M. 10.1101/573576 — evolutionary biology — Posted on 2019-03-11 2340 Positive genetic associations among fitness traits support evolvability of a reef-building coral under multiple stressors Wright, R. M.; Mera, H.; Kenkel, C. D.; Nayfa, M.; Bay, L. K.; Matz, M. V. 10.1101/572321 — evolutionary biology — Posted on 2019-03-11 2341 Symbiont community diversity is more constrained in holobionts that tolerate diverse stressors Howe-Kerr, L.; Bachelot, B.; Wright, R. M.; Kenkel, C. D.; Bay, L. K.; Correa, A. M. S. 10.1101/572479 — ecology — Posted on 2019-03-11 2342 An experimental manipulation of species’ phenologies overturns competitive hierarchies Blackford, C.; Germain, R. M.; Gilbert, B. 10.1101/573204 — ecology — Posted on 2019-03-11 2343 Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters Darbellay, F.; Bochaton, C.; Lopez-Delisle, L.; Mascrez, B.; Tschopp, P.; Delpretti, S.; Zakany, J.; Duboule, D. 10.1101/572875 — developmental biology — Posted on 2019-03-11 2344 The transporters SLC35A1 and SLC30A1 play opposite roles in cell survival upon VSV virus infection Moskovskich, A.; Goldmann, U.; Kartnig, F.; Lindinger, S.; Konecka, J.; Fiume, G.; Girardi, E.; Superti-Furga, G. 10.1101/573253 — cell biology — Posted on 2019-03-11 2345 High-speed multifocal plane fluorescence microscopy for three-dimensional visualisation of beating flagella Wheeler, R. 10.1101/573485 — cell biology — Posted on 2019-03-11 2346 METABOLIC DIVERSITY IN HUMAN NON-SMALL CELL LUNG CANCER CELLS CHEN, P.-H.; Cai, L.; Yang, C.; Kim, J.; Faubert, B.; Boroughs, L.; Ko, B.; Sudderth, J.; McMillan, E. A.; Girard, L.; Peyton, M.; Huffman, K.; Shields, M. D.; Shames, D.; Kim, H. S.; Timmons, B.; Sekine, I.; Britt, R.; Weber, S.; Byers, L. A.; Heymach, J. V.; White, M. A.; Minna, J.; Xiao, G.; DeBerardinis, R. J. 10.1101/561688 — cancer biology — Posted on 2019-03-11 2347 The Mut+ strain of Komagataella phaffii (Pichia pastoris) expresses PAOX1 5 and 10 times faster than Muts and Mut- strains: Evidence that formaldehyde or/and formate are true inducers of AOX. Singh, A.; Narang, A. 10.1101/573519 — bioengineering — Posted on 2019-03-11 2348 The ER membrane protein complex is important for the biogenesis of flavivirus polyproteins Ngo, A. M.; Shurtleff, M. J.; Popova, K. D.; Kulsuptrakul, J.; Weissman, J. S.; Puschnik, A. S. 10.1101/572602 — microbiology — Posted on 2019-03-11 2349 Vertical niche definition of test-bearing protists (Rhizaria) into the twilight zone revealed by in situ imaging Biard, T.; Ohman, M. 10.1101/573410 — ecology — Posted on 2019-03-11 2350 Deregulation of TGF-β1 signaling induces glycolysis by chromatin remodeling in pathogenic TH17 cells Yu, X.; Wang, L.; Han, Z.; Yao, C.; Qiu, R.; Cui, Y.; Dai, D.; Jin, W.; Shen, N. 10.1101/218545 — immunology — Posted on 2019-03-10 2351 Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes Wang, Q.; Pierce-Hoffman, E.; Cummings, B. B.; Karczewski, K. J.; Alfoldi, J.; Francioli, L. C.; Gauthier, L. D.; Hill, A. J.; O'Donnell-Luria, A. H.; Genome Aggregation Database Production Team, ; Genome Aggregation Database Consortium, ; MacArthur, D. G. 10.1101/573378 — genomics — Posted on 2019-03-10 2352 Reliable analysis of clinical tumor-only whole exome sequencing data Oh, S.; Geistlinger, L.; Ramos, M.; Morgan, M.; Waldron, L.; Riester, M. 10.1101/552711 — bioinformatics — Posted on 2019-03-10 2353 Genotype-free demultiplexing of pooled single-cell RNA-seq Xu, J.; Falconer, C.; Coin, L. 10.1101/570614 — bioinformatics — Posted on 2019-03-10 2354 Auxin-sensitive Aux/IAA proteins mediate drought tolerance in Arabidopsis by regulating glucosinolate levels Estelle, M.; Salehin, M.; Li, B.; Tang, M.; Katz, E.; Song, L.; Ecker, J.; Kliebenstein, D. 10.1101/572305 — plant biology — Posted on 2019-03-10 2355 Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes Wang, Q.; Pierce-Hoffman, E.; Cummings, B. B.; Karczewski, K. J.; Alfoldi, J.; Francioli, L. C.; Gauthier, L. D.; Hill, A. J.; O'Donnell-Luria, A. H.; Genome Aggregation Database (gnomAD) Production Te, ; Genome Aggregation Database (gnomAD) Consortium, ; MacArthur, D. G. 10.1101/573378 — genomics — Posted on 2019-03-10 2356 Prevalence and risk factors profile of seropositive Toxoplasmosis gondii infection among apparently immunocompetent Sudanese women Mustafa, M.; Fathy, F.; Mirghani, A.; Mohamed, M. A.; Muneer, M. S.; Ahmed, A. E.; Ali, M. S.; Omer, R. A.; Siddig, E. E.; Mohamed, N. S.; Abd Elkareem, A. M. 10.1101/572800 — microbiology — Posted on 2019-03-10 2357 Real-time Metagenomic Analysis of Undiagnosed Fever Cases Unveils a Yellow Fever Outbreak in Edo State, Nigeria Ajogbasile, F. V.; Oguzie, J. U.; Oluniyi, P. E.; Eromon, P.; Uwanibe, J.; Mehta, S. B.; Siddle, K. J.; Odia, I.; Winnicki, S. M.; Akpede, N.; Akpede, G.; Okogbenin, S.; MacInnis, B. L.; Folarin, O. A.; Schaffner, S. F.; Ogbaini-Emovon, E.; Tomori, O.; Ihekweazu, C.; Sabeti, P. C.; Happi, C. T. 10.1101/572354 — genomics — Posted on 2019-03-10 2358 The life of P.I. - Transitions to Independence in Academia Acton, S. E.; Bell, A.; Toseland, C.; Twelvetrees, A. 10.1101/571935 — scientific communication and education — Posted on 2019-03-10 2359 From prior information to saccade selection: evolution of frontal eye field activity during natural scene search Glaser, J. I.; Wood, D. K.; Lawlor, P. N.; Segraves, M. A.; Kording, K. P. 10.1101/251835 — neuroscience — Posted on 2019-03-10 2360 The optimal odor-receptor interaction network is sparse in olfactory systems: Compressed sensing by nonlinear neurons with a finite dynamic range Qin, S.; Li, Q.; Tang, C.; Tu, Y. 10.1101/464875 — neuroscience — Posted on 2019-03-10 2361 The summary diagram of discovered host immunological pathways against different pathogens and its relation to hypersensitivities Hu, W. 10.1101/006965 — immunology — Posted on 2019-03-10 2362 Molecular properties and evolutionary origins of a parvovirus-derived myosin fusion gene in guinea pigs Valencia-Herrera, I.; Cena-Ahumada, E.; Faunes, F.; Ibarra-Karmy, R.; Gifford, R. J.; Arriagada, G. 10.1101/572735 — evolutionary biology — Posted on 2019-03-10 2363 Bacteria are required for regeneration of the Xenopus tadpole tail Bishop, T. F.; Beck, C. W. 10.1101/319939 — developmental biology — Posted on 2019-03-10 2364 Weak Membrane Interactions Allow Rheb to Activate mTORC1 Signaling Without Major Lysosome Enrichment Angarola, B.; Ferguson, S. M. 10.1101/513473 — cell biology — Posted on 2019-03-10 2365 BORIS/CTCFL promotes a switch from a proliferative towards an invasive phenotype in melanoma cells Janssen, S. M.; Moscona, R.; Elchebly, M.; Papadakis, A. I.; Redpath, M.; Wang, H.; Rubin, E.; van Kempen, L. C.; Spatz, A. 10.1101/560474 — cancer biology — Posted on 2019-03-10 2366 Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics Davis, L. K.; Ford, I. J.; Saric, A.; Hoogenboom, B. 10.1101/571687 — biophysics — Posted on 2019-03-10 2367 Designing a novel multi-epitope T vaccine for \"targeting protein for Xklp-2\" (TPX2) in hepatocellular carcinoma based on immunoinformatics approach Ghahremanifard, P.; Afzali, F.; Rostami, A.; Nayeri, Z.; Bambai, B.; Minuchehr, Z. 10.1101/570952 — bioinformatics — Posted on 2019-03-10 2368 Looking for Therapeutic Antibodies in Next Generation Sequencing Repositories Krawczyk, K.; Kovaltsuk, A.; Raybould, M.; Deane, C. 10.1101/572958 — bioinformatics — Posted on 2019-03-10 2369 Landscape and dynamics of the transcriptional regulatory network during natural killer cell differentiation Li, K.; Wu, Y.; Li, Y.; Yu, Q.; Tian, Z.; Wei, H.; Qu, K. 10.1101/572768 — bioinformatics — Posted on 2019-03-10 2370 Temperature drives the evolution and global distribution of avian eggshell colour Wisocki, P. A.; Kennelly, P.; Rojas Rivera, I.; Cassey, P.; Hanley, D. 10.1101/559435 — ecology — Posted on 2019-03-10 2371 How many cubs can a mum nurse? Maternal age and size influence litter size in polar bears Folio, D. M.; Aars, J.; Gimenez, O.; Derocher, A. E.; Wiig, O.; Cubaynes, S. 10.1101/532945 — ecology — Posted on 2019-03-10 2372 Recognition Genes Which Are Relative With Cancer By Deep Learning Algorithm Zou, B. 10.1101/571851 — bioinformatics — Posted on 2019-03-09 2373 Temporal variation of fatty acid composition and pesticides in honeybees Apis mellifera and beebread Gooley, Z. C.; Gooley, A. 10.1101/572149 — zoology — Posted on 2019-03-09 2374 Intercellular positive-feedback loops promote the evolutionary stability of microbial cooperative behaviors Ben-Zion, I.; Eldar, A. 10.1101/571562 — systems biology — Posted on 2019-03-09 2375 Cytokinin functions as an asymmetric and anti-gravitropic signal in lateral roots Waidmann, S.; Ruiz Rosquete, M.; Scholler, M.; Lindner, H.; LaRue, T.; Sarkel, E.; Petrik, I.; Dunser, K.; Martopawiro, S.; Sasidharan, R.; Novak, O.; Wabnik, K.; Dinneny, J. R.; Kleine-Vehn, J. 10.1101/572941 — plant biology — Posted on 2019-03-09 2376 3D spatially-resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression Segovia-Miranda, F.; Morales-Navarrete, H.; Kucken, M.; Moser, V.; Seifert, S.; Repnik, U.; Rost, F.; Hendriks, A.; Hinz, S.; Rocken, C.; Luthjohann, D.; Kalaidzidis, Y.; Schafmayer, C.; Brusch, L.; Hampe, J.; Zerial, M. 10.1101/572073 — pathology — Posted on 2019-03-09 2377 Cellular and network mechanisms may generate sparse coding of sequential object encounters in hippocampal-like circuits Trinh, A.-T.; Clarke, S. E.; Harvey-Girard, E.; Maler, L. 10.1101/571414 — neuroscience — Posted on 2019-03-09 2378 Histological validation of per-bundle water diffusion metrics within a region of fiber crossing following axonal degeneration Rojas-Vite, G.; Coronado-Leija, R.; Narvaez-Delgado, O.; Ramirez-Manzanares, A.; Marroquin, J.-L.; Noguez-Imm, R.; Aranda, M. L.; Scherrer, B.; Larriva-Sahd, J.; Concha, L. 10.1101/571539 — neuroscience — Posted on 2019-03-09 2379 Tactile sensory channels over-ruled by frequency decoding system that utilizes spike pattern regardless of receptor type Birznieks, I.; McIntyre, S.; Nilsson, H. M.; Nagi, S. S.; Macefield, V. G.; Mahns, D. A.; Vickery, R. M. 10.1101/570929 — neuroscience — Posted on 2019-03-09 2380 Event segmentation reveals working memory forgetting rate Jafarpour, A.; Buffalo, E.; Knight, R.; Collins, A. 10.1101/571380 — neuroscience — Posted on 2019-03-09 2381 Behavioural and neural limits in competitive decision making: The roles of outcome, opponency and observation Dyson, B.; Steward, B. A.; Meneghetti, T.; Forder, L. 10.1101/571257 — neuroscience — Posted on 2019-03-09 2382 Analytic Model of fMRI BOLD Signals for Separable Metrics of Neural and Metabolic Activity Schaper, C. 10.1101/573006 — neuroscience — Posted on 2019-03-09 2383 SPiQE: an automated analytical tool for detecting and characterising fasciculations in amyotrophic lateral sclerosis Bashford, J.; Wickham, A.; Iniesta, R.; Drakakis, E.; Boutelle, M.; Mills, K.; Shaw, C. 10.1101/571893 — neuroscience — Posted on 2019-03-09 2384 Targeting MOG to skin macrophages prevents EAE in macaques through TGFβ-induced peripheral tolerance Fovet, C.-M.; Stimmer, L.; Contreras, V.; Horellou, P.; Hubert, A.; Seddiki, N.; Chapon, C.; Tricot, S.; Leroy, C.; Flament, J.; Massonneau, J.; Tchitchek, N.; 't Hart, B.; Zurawski, S.; Klucar, P.; Deiva, K.; Zurawski, G.; Oh, S.; Le Grand, R.; Serguera, C. 10.1101/571828 — immunology — Posted on 2019-03-09 2385 Lactate potentiates differentiation and expansion of cytotoxic T cells Rundqvist, H.; Velica, P.; Barbieri, L.; Gameiro, P.; Cunha, P.; Gojkovic, M.; Mijwel, S.; Ahlstedt, E.; Foskolou, I. P.; Ruiz-Perez, M.; Arsenian-Henriksson, M.; Ule, J.; Ostman, A.; Johnson, R. 10.1101/571745 — immunology — Posted on 2019-03-09 2386 Fine mapping using whole-genome sequencing confirms anti Mullerian hormone as a major gene for sex determination in farmed Nile tilapia (Oreochromis niloticus L.) Caceres, G.; Lopez, M. E.; Cadiz, M. I.; Yoshida, G.; Jedlicki, A.; Palma-Vejares, R.; Travisany, D.; Diaz-Dominguez, D.; Maass, A.; Lhorente, J.-P.; Soto, J.; Salas, D.; Yanez, J. M. 10.1101/573014 — genomics — Posted on 2019-03-09 2387 CRISPR disruption and UK Biobank analysis of a highly conserved polymorphic enhancer suggests its role in anxiety and male alcohol intake. McEwan, A. R.; Hay, E.; Davidson, C.; Turnbull, Y.; Marini, P.; Wilson, D.; McIntosh, A.; Adams, M. J.; Murgatroyd, C.; Barrett, P.; Delibegovic, M.; Clarke, T.-K.; MacKenzie, A. 10.1101/572065 — genetics — Posted on 2019-03-09 2388 Evolutionary stability of collateral sensitivity to antibiotics in the model pathogen Pseudomonas aeruginosa Barbosa, C.; Roemhild, R.; Rosenstiel, P.; Schulenburg, H. 10.1101/570663 — evolutionary biology — Posted on 2019-03-09 2389 Evolution, not transgenerational plasticity, explains the divergence of acorn ant thermal tolerance across an urban-rural temperature cline Martin, R. A.; Chick, L. D.; Yilmaz, A. R.; Diamond, S. E. 10.1101/571521 — evolutionary biology — Posted on 2019-03-09 2390 Soil protist diversity in the Swiss western Alps is better predicted by topo-climatic than by edaphic variables Seppey, C. V. W.; Broennimann, O.; Buri, A.; Yashiro, E.; Pinto-Figueroa, E.; Singer, D.; Blandenier, Q.; Mitchell, E. A. D.; Niculita Hirzel, H.; Guisan, A.; Lara, E. 10.1101/571760 — ecology — Posted on 2019-03-09 2391 Survival of prey growing through gape-limited predators Anderson, J. J. 10.1101/571356 — ecology — Posted on 2019-03-09 2392 Looking for Therapeutic Antibodies in Next Generation Sequencing Repositories Krawczyk, K.; Kovaltsuk, A.; Raybould, M.; Deane, C. M. 10.1101/572958 — bioinformatics — Posted on 2019-03-09 2393 A Bayesian framework for inferring the influence of sequence context on single base modifications Ling, G.; Miller, D.; Nielsen, R.; Stern, A. 10.1101/571646 — bioinformatics — Posted on 2019-03-09 2394 SF3B1ness score: screening SF3B1 mutation status from over 60,000 transcriptomes based on a machine learning approach Shiraishi, Y.; Chiba, K.; Okada, A. 10.1101/572834 — bioinformatics — Posted on 2019-03-09 2395 ExpansionHunter: A sequence-graph based tool to analyze variation in short tandem repeat regions Dolzhenko, E.; Deshpande, V.; Schlesinger, F.; Krusche, P.; Petrovski, R.; Chen, S.; Emig-Agius, D.; Gross, A.; Narzisi, G.; Bowman, B.; Scheffler, K.; van Vugt, J. J. F. A.; French, C.; Sanchis-Juan, A.; Ibanez, K.; Tucci, A.; Lajoie, B.; Veldink, J. H.; Raymond, L.; Taft, R. J.; Bentley, D. R.; Eberle, M. A. 10.1101/572545 — bioinformatics — Posted on 2019-03-09 2396 Revealing new therapeutic opportunities through drug target prediction via class imbalance-tolerant machine learning Liang, S.; Yu, H. 10.1101/572420 — bioinformatics — Posted on 2019-03-09 2397 Nicotinamide Deficiency In Primary Open-Angle Glaucoma Kouassi Nzoughet, J.; Chao de la Barca, J. M.; Guehlouz, K.; Leruez, S.; Coulbault, L.; Allouche, S.; Bocca, C.; Muller, J.; Amati-Bonneau, P.; Gohier, P.; Bonneau, D.; Simard, G.; Milea, D.; Lenaers, G.; Procaccio, V.; Reynier, P. 10.1101/571638 — biochemistry — Posted on 2019-03-09 2398 Transcriptional signatures of invasiveness in Meloidogyne incognita populations from sub-Saharan Africa Cox, D. E.; Reilly, B.; Warnock, N. D.; Dyer, S.; Sturrock, M.; Cortada, L.; Coyne, D.; Maule, A. G.; Dalzell, J. J. 10.1101/570770 — animal behavior and cognition — Posted on 2019-03-09 2399 Direct control of shell regeneration by the mantle tissue in the pearl oyster Pinctada fucata via accelerating CaCO3 nucleation Huang, J.; Liu, Y.; Jiang, T.; Dong, W.; Zheng, G.; Xie, L.; Zhang, R. 10.1101/572024 — zoology — Posted on 2019-03-09 2400 A distinct pool of Nav1.5 channels at the lateral membrane of murine ventricular cardiomyocytes Rougier, J.-S.; Essers, M. C.; Gillet, L.; Guichard, S.; Sonntag, S.; Shmerling, D.; Abriel, H. 10.1101/572180 — physiology — Posted on 2019-03-09 2401 Time-course of population activity along the dorsoventral extent of the superior colliculus during delayed saccade tasks Massot, C.; Jagadisan, U. K.; Gandhi, N. J. 10.1101/571307 — neuroscience — Posted on 2019-03-09 2402 Corticotropin-Releasing Hormone Signaling in the Oval Bed Nucleus of the Stria Terminalis Mediates Chronic Stress-Induced Negative Valence Behaviors Associated with Anxiety Hu, P.; Maita, I.; Kwok, C.; Gu, E.; Gergues, M.; Liu, J.; Pang, Z.; Swaab, D. F.; Lucassen, P. J.; Roepke, T. A.; Samuels, B. A. 10.1101/572966 — neuroscience — Posted on 2019-03-09 2403 Resting-state functional connectivity modulates the BOLD activation induced by nucleus accumbens stimulation in the swine brain Cho, S.; Hachmann, J. T.; Balzekas, I.; In, M.-H.; Andres-Beck, L. G.; Lee, K. H.; Min, H.-K.; Jo, H. J. 10.1101/571513 — neuroscience — Posted on 2019-03-09 2404 Large-scale chemical-genetics of the human gut bacterium Bacteroides thetaiotaomicron Liu, H.; Price, M. N.; Carlson, H. K.; Chen, Y.; Ray, J.; Shiver, A. L.; Petzold, C. J.; Huang, K. C.; Arkin, A. P.; Deutschbauer, A. 10.1101/573055 — microbiology — Posted on 2019-03-09 2405 Genome-wide association study and low-cost genomic predictions for growth and fillet yield in Nile tilapia (Oreochromis niloticus) Yoshida, G.; Lhorente, J. P.; Correa, K.; Soto, J.; Salas, D.; Yanez, J. 10.1101/573022 — genomics — Posted on 2019-03-09 2406 The optimal discovery procedure for significance analysis of general gene expression studies Bass, A. J.; Storey, J. D. 10.1101/571992 — bioinformatics — Posted on 2019-03-09 2407 A low-cost, open-source framework for tracking and behavioural analysis of animals in aquatic ecosystems Francisco, F. A.; Nuehrenberg, P.; Jordan, A. 10.1101/571232 — animal behavior and cognition — Posted on 2019-03-09 2408 Recent and rapid colonization of the Lesser Sundas Archipelago from adjacent Sundaland by seven amphibian and reptile species Reilly, S. B.; Stubbs, A. L.; Karin, B. R.; Arida, E.; Iskandar, D. T.; McGuire, J. A. 10.1101/571471 — zoology — Posted on 2019-03-09 2409 Active Efficient Coding Explains the Development of Binocular Vision and its Failure in Amblyopia Eckmann, S.; Klimmasch, L.; Shi, B. E.; Triesch, J. 10.1101/571802 — neuroscience — Posted on 2019-03-09 2410 Automated and Manual Quantification of Tumour Cellularity in Digital Slides for Tumour Burden Assessment Akbar, S.; Peikari, M.; Salama, S.; Panah, A. Y.; Nofech-Momes, S.; Martel, A. L. 10.1101/571190 — pathology — Posted on 2019-03-09 2411 Aberrant Population Receptive Fields in Human Albinism Duwell, E. J.; Woertz, E. N.; Mathis, J.; Carroll, J.; DeYoe, E. A. 10.1101/572289 — neuroscience — Posted on 2019-03-09 2412 Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development Baumgarten, S.; Bryant, J. M.; Sinha, A.; Reyser, T.; Preiser, P. R.; Dedon, P. C.; Scherf, A. 10.1101/572891 — molecular biology — Posted on 2019-03-09 2413 Thermal preferences drive behavioural responses but not biomass responses of predatory fishes to lake morphometry Bartley, T. J.; Guzzo, M. M.; Cazelles, K.; Verville, A.; McMeans, B. C.; McCann, K. S. 10.1101/572925 — ecology — Posted on 2019-03-09 2414 Determining the Minimal Background Area for Species Distribution Models: MinBAR Package Rotllan-Puig, X.; Traveset, A. 10.1101/571182 — ecology — Posted on 2019-03-09 2415 Cascaded-CNN: Deep Learning to Predict Protein Backbone Structure from High-Resolution Cryo-EM Density Maps Moritz, S.; Pfab, J.; Si, D.; Wu, T.; Hou, J.; Cheng, J.; Cao, R.; Wang, L. 10.1101/572990 — molecular biology — Posted on 2019-03-09 2416 Distinct Regulation of Bioenergetics and Translation by Gp I mGluRs and NMDARs Ghosh Dastidar, S.; Chakraborty, S.; Chattarji, S.; Bhattacharya, A.; Muddashetty, R. 10.1101/552638 — neuroscience — Posted on 2019-03-09 2417 Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance in a model gut microbiota Aranda-Diaz, A.; Obadia, B.; Thomsen, T.; Hallberg, Z. F.; Guvener, Z. T.; Huang, K. C.; Ludington, W. B. 10.1101/538132 — microbiology — Posted on 2019-03-09 2418 Machine learning in drug development Sahli Costabal, F.; Seo, K.; Ashley, E.; Kuhl, E. 10.1101/545863 — biophysics — Posted on 2019-03-09 2419 Wolbachia pipientis occurs in Aedes aegypti populations in New Mexico and Florida, USA Kulkarni, A.; Yu, W.; Jiang, J.; Sanchez, C.; Karna, A. K.; Martinez, K. J. L.; Hanley, K. A.; Buenemann, M.; Hansen, I. A.; Xue, R.-d.; Ettestad, P.; Melman, S.; Duguma, D.; Debboun, M.; Xu, J. 10.1101/455014 — ecology — Posted on 2019-03-09 2420 Jag1 coordinates release from multipotency with cell fate choice in the developing pancreas Seymour, P. A.; Collin, C. A.; Jorgensen, M. C.; Imayoshi, I.; Honnens de Lichtenberg, K. H.; Kopan, R.; Kageyama, R.; Serup, P. 10.1101/336529 — developmental biology — Posted on 2019-03-09 2421 Identifying drug combinations of individual cancer patients by personalized drug controller method Guo, W.; Zhang, S.-W.; Zeng, T.; Chen, L. 10.1101/571620 — systems biology — Posted on 2019-03-09 2422 Mammalian olfaction is a high temporal bandwidth sense Erskine, A.; Ackels, T.; Dasgupta, D.; Fukunaga, I.; Schaefer, A. T. 10.1101/570689 — neuroscience — Posted on 2019-03-09 2423 The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs Piskacek, M.; Havelka, M.; Jendruchova, K.; Knight, A.; Keegan, L. P. 10.1101/570598 — molecular biology — Posted on 2019-03-09 2424 A General Statistic to Test an Optimally WeightedCombination of Common and/or Rare Variants Zhang, J.; WU, B.; Sha, Q.; zhang, s.; wang, x. 10.1101/572115 — genetics — Posted on 2019-03-09 2425 Designing a novel multi-epitope T vaccine for targeting protein for Xklp-2 (TPX2) in hepatocellular carcinoma based on immunoinformatics approach Ghahremanifard, P.; Afzali, F.; Rostami, A.; Nayeri, Z.; Minuchehr, Z. 10.1101/570952 — bioinformatics — Posted on 2019-03-09 2426 Plant evolution further threatens declining pollinator populations Weinbach, A.; Loeuille, N.; Rohr, R. P. 10.1101/570580 — ecology — Posted on 2019-03-09 2427 Chromosomes function as a barrier to mitotic spindle bipolarity in polyploid cells Goupil, A.; Nano, M.; Letort, G.; Gogendeau, D.; Pennetier, C.; Basto, R. 10.1101/572099 — cell biology — Posted on 2019-03-09 2428 Bid as a novel interacting partner of IRE1 differentially regulating its RNAse activity Bashir, S.; Fazili, K. M. 10.1101/572222 — cell biology — Posted on 2019-03-09 2429 Oncogenic signaling alters cell shape and mechanics to facilitate cell division under confinement. Matthews, H. K.; Ganguli, S.; Plak, K.; Taubenberger, A. V.; Piel, M.; Guck, J.; Baum, B. 10.1101/571885 — cell biology — Posted on 2019-03-09 2430 Structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma Lopez, G.; Conkrite, K. L.; Doepner, M.; Rathi, K. S.; Modi, A.; Vaksman, Z.; Farra, L. M.; Hyson, E.; Noureddine, M.; Wei, J. S.; Smith, M. A.; Asgharzadeh, S.; Seeger, R. C.; Khan, J.; Guidry Auvil, J. M.; Gerhard, D. S.; Maris, J. M.; Diskin, S. J. 10.1101/572248 — cancer biology — Posted on 2019-03-09 2431 The orientation of a membrane probe from structural analysis by enhanced Raman scattering Hughes, H. J.; Demers, S. M. E.; Zhang, A.; Hafner, J. H. 10.1101/572529 — biophysics — Posted on 2019-03-09 2432 Charting shared developmental trajectories of cortical thickness and structural connectivity in childhood and adolescence Ball, G.; Beare, R.; Seal, M. L. 10.1101/572552 — neuroscience — Posted on 2019-03-09 2433 Genetic analysis of TP53 gene mutations in exon 4 and exon 8 among esophageal cancer patients in Sudan Eltaher, S. M.; Idris, A. B.; H, M. A.; Mohamed Yousif, M. Y.; Mohamed, N. S.; Abdel Hamid, M. M.; Elsiddig, K. E.; Yousif, G. M.; Hassan, M. A. 10.1101/572214 — cancer biology — Posted on 2019-03-09 2434 Modulation of Rapid Visual Responses during Reaching by Multimodal Stimuli Glover, I. S.; Baker, S. N. 10.1101/570796 — neuroscience — Posted on 2019-03-09 2435 Altered structural brain asymmetry in autism spectrum disorder: large-scale analysis via the ENIGMA Consortium Postema, M. C.; van Rooij, D.; Anagnostou, E.; Arango, C.; Auzias, G.; Behrmann, M.; Filho, G. B.; Calderoni, S.; Calvo, R.; Daly, E.; Deruelle, C.; Di Martino, A.; Dinstein, I.; Duran, F. L. S.; Durston, S.; Ecker, C.; Ehrlich, S.; Fair, D.; Fedor, J.; Feng, X.; Fitzgerald, J.; Floris, D. L.; Freitag, C. M.; Gallagher, L.; Glahn, D. C.; Gori, I.; Haar, S.; Hoekstra, L.; Jahansad, N.; Jalbrzikowski, M.; Janssen, J.; King, J. A.; Zaro, L. L.; Lerch, J. P.; Luna, B.; Martinho, M. M.; McGrath, J.; Medland, S. E.; Muratori, F.; Murphy, C. M.; Murphy, D. G. M.; O'Hearn, K.; Oranje, B.; Parellada, 10.1101/570655 — neuroscience — Posted on 2019-03-09 2436 Resistance Rate Distribution of MDR-TB Among Pulmonary Tuberculosis Patients Attending Nnamdi Azikiwe University Teaching Hospital Nnewi and ST Patrick’S Hospital Mile 4 Abakiliki in Southeast Nigeria Okoro, C. E.; Akujobi, C. N.; Udoh, I. P.; Ibhawaegbele, S. O.; Ezema, C. I.; Ezeugwu, U. A.; Dozie-Nwakile, O. C.; Okpe, A. C. 10.1101/570416 — microbiology — Posted on 2019-03-09 2437 Outbreak of murine infection with Clostridium difficile associated with the administration of a pre- and peri-natal methyl-donor diet Mau, T.; Eckley, S. S.; Bergin, I. L.; Saund, K.; Villano, J. S.; Vendrov, K. C.; Snitkin, E. S.; Young, V. B.; Yung, R. 10.1101/565762 — epidemiology — Posted on 2019-03-09 2438 Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration Wei, L.; Blader, P.; Roussigne, M. 10.1101/570820 — cell biology — Posted on 2019-03-09 2439 An atlas of anterior hox gene expression in the embryonic sea lamprey head: hox-code evolution in vertebrates Parker, H. J.; Bronner, M. E.; Krumlauf, R. 10.1101/571448 — developmental biology — Posted on 2019-03-09 2440 The Neural Basis of Shared Preference Learning Farmer, H.; Hamilton, A.; Hertz, U. 10.1101/570762 — neuroscience — Posted on 2019-03-09 2441 Conserving unprotected important coastal habitats in the Yellow Sea: shorebird occurrence, distribution and food resources at Lianyungang Chan, Y.-C.; Peng, H.-B.; Han, Y.-X.; Chung, S. S.-W.; Li, J.; Zhang, L.; Piersma, T. 10.1101/570556 — ecology — Posted on 2019-03-09 2442 Comparison Between Normobaric Hypoxia Altitude Simulation Test and Altitude Hypoxia Predictive Equations in Cystic Fibrosis Patients Costa, C.; Barros, A.; Rodrigues, J. V.; Staats, R.; Alves, M.; Cardim, P.; Lopes, C.; Barbara, C.; Moita, L.; Moreira, S. 10.1101/570754 — pathology — Posted on 2019-03-09 2443 In search of Universal Cortical Power Changes Linked to NMDA-Antagonist based Anesthetic Induced Reductions in Consciousness. Pelentritou, A.; Kuhlmann, L.; Cormack, J.; Mcguigan, S.; Woods, W.; Muthukumaraswamy, S.; Liley, D. 10.1101/572636 — neuroscience — Posted on 2019-03-09 2444 Selective Liposomal Transport Through Blood Brain Barrier Disruption in Ischaemic Stroke Reveals Two Distinct Therapeutic Opportunities Al-Ahmady, Z. S.; Jasim, D.; Ahmad, S.; Wong, R.; Haley, M.; Coutts, G.; Schiessl, I.; Allan, S. M.; Kostarelos, K. 10.1101/570234 — neuroscience — Posted on 2019-03-09 2445 Fear Learning Induces Long-Lasting Changes in Gene Expression and Pathway Specific Presynaptic Growth Dillingham, B. C.; Cameron, P.; Pieraut, S.; Cardozo, L. M.; Yoo, E. J.; Maximov, A.; Stowers, L.; Mayford, M. 10.1101/571331 — neuroscience — Posted on 2019-03-09 2446 Modeling decision-making under uncertainty: a direct comparison study between human and mouse gambling data Cabeza Alvarez, L.; Giustiniani, J.; Chabin, T.; Ramadan, B.; Joucla, C.; Nicolier, M.; Pazart, L.; Haffen, E.; Fellmann, D.; Gabriel, D.; Peterschmitt, Y. 10.1101/570499 — neuroscience — Posted on 2019-03-09 2447 The effect of diffusion on asymmetric spin echo based quantitative BOLD: An investigation of the origin of deoxygenated blood volume overestimation Stone, A. J.; Holland, N. C.; Berman, A. J.; Blockley, N. 10.1101/570697 — neuroscience — Posted on 2019-03-09 2448 Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank Van Hout, C. V.; Tachmazidou, I.; Backman, J. D.; Hoffman, J. X.; Yi, B.; Pandey, A.; Gonzaga-Jauregui, C.; Khalid, S.; Liu, D.; Banerjee, N.; Li, A. H.; O'Dushlaine, C.; Marcketta, A.; Staples, J.; Schumann, C.; Hawes, A.; Maxwell, E.; Barnard, L.; Lopez, A.; Penn, J.; Habegger, L.; Blumenfeld, A. L.; Yadav, A.; Praveen, K.; Jones, M.; Salerno, W. J.; Chung, W. K.; Surakka, I.; Willer, C. J.; Hveem, K.; Leader, J. B.; Carey, D. J.; Ledbetter, D. H.; Cardon, L.; Yancopoulos, G. D.; Economides, A.; Coppola, G.; Shuldiner, A. R.; Balasubramanian, S.; Cantor, M.; Nelson, M. R.; Whittaker, J. C.; 10.1101/572347 — genomics — Posted on 2019-03-09 2449 Transfer of Xanthomonas campestris pv. arecae, and Xanthomonas campestris pv. musacearum to Xanthomonas vasicola (Vauterin) as Xanthomonas vasicola pv. arecae comb. nov., and Xanthomonas vasicola pv. musacearum comb. nov. and description of Xanthomonas vasicola pv. vasculorum pv. nov. Studholme, D. J.; Wicker, E.; Bogdanove, A.; Broders, K.; Dubrow, Z.; Grant, M.; Jones, J. B.; Karamura, G.; Lang, J.; Leach, J.; Abrare, S. M.; Mahuku, G.; Nakato, G. V.; Coutinho, T.; Smith, J.; Bull, C. 10.1101/571166 — microbiology — Posted on 2019-03-09 2450 Variation of immune cell responses in humans reveals sex-specific coordinated signaling across cell types Fragiadakis, G. K.; Bjornson-Hooper, Z. B.; Madhireddy, D.; Sachs, K.; Spitzer, M. H.; Bendall, S. C.; Nolan, G. P. 10.1101/567784 — immunology — Posted on 2019-03-09 2451 Comparative analysis of EHR-based stroke phenotyping methods, their applications, and interpretation Thangaraj, P. M.; Kummer, B.; Lorberbaum, T.; Elkind, M.; Tatonetti, N. P. 10.1101/565671 — bioinformatics — Posted on 2019-03-09 2452 The shape of gene expression distributions matter: how incorporating distribution shape improves the interpretation of cancer transcriptomic data de Torrente, L.; Zimmerman, S.; Suzuki, M.; Christopeit, M.; Greally, J. M.; Mar, J. 10.1101/572693 — bioinformatics — Posted on 2019-03-09 2453 The Anaerobic Efflux Pump MdtEF-TolC Confers Resistance to Cationic Biocides Novoa, D.; Conroy-Ben, O. 10.1101/570408 — microbiology — Posted on 2019-03-09 2454 Pulcherrimin formation controls growth arrest of the Bacillus subtilis biofilm Arnaouteli, S.; Matoz Fernandez, D. A.; Porter, M.; Kalamara, M.; Abbott, J.; MacPhee, C.; Davidson, F.; Stanley-Wall, N. 10.1101/570630 — microbiology — Posted on 2019-03-09 2455 Genetic determinants in Salmonella enterica serotype Typhimurium required for overcoming stressors in the host environment Mandal, R. K.; Jiang, T.; Kwon, Y. M. 10.1101/571273 — microbiology — Posted on 2019-03-09 2456 The type VII secretion system protects Staphylococcus aureus against antimicrobial host fatty acids Kengmo Tchoupa, A.; Jones, R. A.; Kuroki, A.; Alam, M. T.; Perrier, S.; Chen, Y.; Unnikrishnan, M. 10.1101/572172 — microbiology — Posted on 2019-03-09 2457 The ER membrane protein complex is important for the biogenesis of flavivirus polyproteins Ngo, A. M.; Shurtleff, M. J.; Popova, K. D.; Kulsuptrakul, J.; Weissman, J. S.; Puschnik, A. S. 10.1101/572602 — microbiology — Posted on 2019-03-09 2458 DNA damage-specific effects of Tel1/ATM and γH2A/γH2AX on checkpoint signaling in Saccharomyces cerevisiae Siler, J.; Huo, N.; Liu, Z.; Qin, Y.; Bi, X. 10.1101/572271 — molecular biology — Posted on 2019-03-09 2459 Short translational ramp determines efficiency of protein synthesis Verma, M.; Choi, J.; Cottrell, K. A.; Lavagnino, Z.; Thomas, E. N.; Pavlovic Djuranovic, S.; Szczesny, P.; Piston, D. W.; Zaher, H.; Puglisi, J. D.; Djuranovic, S. 10.1101/571059 — molecular biology — Posted on 2019-03-09 2460 Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics Ersoy, S. C.; Abdelhady, W.; Li, L.; Chambers, H. F.; Xiong, Y. Q.; Bayer, A. 10.1101/570424 — microbiology — Posted on 2019-03-09 2461 Development, characterization and standardization of a nose-only inhalation exposure system for exposure of rabbits to small particle aerosols containing Francisella tularensis. O'Malley, K. J.; Bowling, J. D.; Barry, E. M.; Hazlett, K. R. O.; Reed, D. S. 10.1101/570432 — microbiology — Posted on 2019-03-09 2462 The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA repression Duszczyk, M. M.; Wischnewski, H.; Kazeeva, T.; Loughlin, F. E.; von Schroetter, C.; Pradere, U.; Hall, J.; Ciaudo, C.; Allain, F. H.- T. 10.1101/572156 — molecular biology — Posted on 2019-03-09 2463 Selective autophagic clearance of protein aggregates is mediated by the autophagy receptor, TAX1BP1 Sarraf, S. A.; Shah, H. V.; Kanfer, G.; Ward, M. E.; Youle, R. J. 10.1101/558767 — cell biology — Posted on 2019-03-09 2464 Balanced internal hydration discriminates substrate binding to respiratory complex I Teixeira, M. H.; Arantes, G. M. 10.1101/572404 — biophysics — Posted on 2019-03-09 2465 Roost selection by male northern long-eared bats (Myotis septentrionalis) in a managed fire-adapted forest Alston, J.; Abernethy, I.; Keinath, D.; Goheen, J. 10.1101/487256 — zoology — Posted on 2019-03-08 2466 Optic flow helps explain gulls’ altitude control over seas Serres, J. R.; Evans, T. J.; Akesson, S.; Duriez, O.; Shamoun-Baranes, J. Z.; Ruffier, F.; Hedenstrom, A. 10.1101/569194 — neuroscience — Posted on 2019-03-08 2467 Distinct Narrow and Broadband Gamma Responses in Human Visual Cortex Bartoli, E.; Bosking, W.; Li, Y.; Beauchamp, M. S.; Yoshor, D.; Foster, B. 10.1101/572313 — neuroscience — Posted on 2019-03-08 2468 Risky Decision-Making Predicts Dopamine Release Dynamics in Nucleus Accumbens Shell Freels, T. G.; Gabriel, D. B. K.; Lester, D. B.; Simon, N. W. 10.1101/572263 — neuroscience — Posted on 2019-03-08 2469 Connectional heterogeneity in the mouse auditory corticocollicular system Yudintsev, G.; Asilador, A.; Coppinger, M.; Nair, K.; Prasad, M.; Llano, D. A. 10.1101/571711 — neuroscience — Posted on 2019-03-08 2470 Blue light induces neuronal-activity-regulated gene expression in the absence of optogenetic proteins Tyssowski, K. M.; Gray, J. M. 10.1101/572370 — neuroscience — Posted on 2019-03-08 2471 Insect-symbiont gene expression in the midgut bacteriocytes of a blood-sucking parasite Husnik, F.; Hypsa, V.; Darby, A. 10.1101/572495 — genomics — Posted on 2019-03-08 2472 A chronology of multicellularity evolution in cyanobacteria Hammerschmidt, K.; Landan, G.; Tria, F. D.; Dagan, T. 10.1101/570788 — evolutionary biology — Posted on 2019-03-08 2473 Associations among Fish Length, Dam Passage History, and Survival to Adulthood in Two At-Risk Species of Pacific Salmon Faulkner, J. R.; Bellerud, B. L.; Widener, D. L.; Zabel, R. W. 10.1101/572594 — ecology — Posted on 2019-03-08 2474 COMMD1 and PtdIns(4,5)P2 interaction maintain ATP7B copper transporter trafficking fidelity in HepG2 cells Stewart, D. J.; Short, K. K.; Maniaci, B. N.; Burkhead, J. L. 10.1101/572578 — cell biology — Posted on 2019-03-08 2475 Mechanism of pharmacochaperoning in KATP channels revealed by cryo-EM Martin, G. M.; Sung, M. W.; Yang, Z.; Innes, L. M.; Kandasamy, B.; David, L.; Yoshioka, C.; Shyng, S.-L. 10.1101/572297 — biophysics — Posted on 2019-03-08 2476 Pervasive head-to-tail insertions of DNA templates mask desired CRISPR/Cas9-mediated genome editing events Skryabin, B. V.; Gubar, L.; Seeger, B.; Kaiser, H.; Stegemann, A.; Roth, J.; Meuth, S. G.; Pavenstadt, H.; Sherwood, J.; Pap, T.; Wedlich-Soldner, R.; Sunderkotter, C.; Schwartz, Y. B.; Brosius, J.; Rozhdestvensky, T. S. 10.1101/570739 — genetics — Posted on 2019-03-08 2477 The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes Hogan, J. D.; Keenan, J. L.; Luo, L.; Hawkins, D. Y.; Ibn-Salem, J.; Lamba, A.; Schatzberg, D.; Piacentino, M. L.; Zuch, D. T.; Core, A. B.; Blumberg, C.; Timmermann, B.; Grau, J. H.; Speranza, E.; Andrade-Navarro, M. A.; Irie, N.; Poustka, A. J.; Bradham, C. 10.1101/572388 — developmental biology — Posted on 2019-03-08 2478 In vitro transposon targeting using a catalytically inactive Cas9 Bhatt, S.; Chalmers, R. 10.1101/571653 — biochemistry — Posted on 2019-03-08 2479 Natural global motion processing by populations of direction-selective retinal ganglion cells Cafaro, J.; Zylberberg, J.; Field, G. 10.1101/572438 — neuroscience — Posted on 2019-03-08 2480 Functionally Coherent Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling Overton, I. M.; Sims, A. H.; Owen, J. A.; Heale, B.; Ford, M. J.; Lubbock, A. L. R.; Pairo-Castineira, E.; Essafi, A. 10.1101/455709 — systems biology — Posted on 2019-03-08 2481 To cure or not to cure: consequences of immunological interactions in CML treatment Cesar Fassoni, A.; Roeder, I.; Glauche, I. 10.1101/494575 — systems biology — Posted on 2019-03-08 2482 12h-clock control of central dogma information flow by XBP1s Pan, Y.; Ballance, H.; Schnytzer, Y.; Chen, X.; Levy, O.; Coarfa, C.; Zhu, B. 10.1101/559039 — systems biology — Posted on 2019-03-08 2483 Optimization of the experimental parameters of the ligase cycling reaction Schlichting, N.; Reinhardt, F.; Jager, S.; Schmidt, M.; Kabisch, J. 10.1101/510768 — synthetic biology — Posted on 2019-03-08 2484 beditor: A computational workflow for designing libraries of guide RNAs for CRISPR-mediated base editing Dandage, R.; Despres, P. C.; Yachie, N.; Landry, C. R. 10.1101/426973 — synthetic biology — Posted on 2019-03-08 2485 A highly predictive signature of cognition and brain atrophy for progression to Alzheimer’s dementia Tam, A.; Dansereau, C.; Iturria-Medina, Y.; Urchs, S.; Orban, P.; Sharmarke, H.; Breitner, J.; Bellec, P.; Alzheimer's Disease Neuroimaging Initiative, 10.1101/352344 — neuroscience — Posted on 2019-03-08 2486 Explicit Neural Models for Flip-Flops and Oscillators Generate Phenomena of Short-Term Memory and Electroencephalography Yoder, L. 10.1101/403196 — neuroscience — Posted on 2019-03-08 2487 Pre-stimulus feedback connectivity biases the content of visual experiences Rassi, E.; Wutz, A.; Mueller-Voggel, N.; Weisz, N. 10.1101/437152 — neuroscience — Posted on 2019-03-08 2488 Altered brain morphology in boys with attention-deficit/hyperactivity disorder with and without comorbid conduct disorder/oppositional defiant disorder Vetter, N. C.; Backhausen, L. L.; Buse, J.; Roessner, V.; Smolka, M. N. 10.1101/553552 — neuroscience — Posted on 2019-03-08 2489 CHIME: CMOS-hosted in-vivo microelectrodes for massively scalable neuronal recordings Kollo, M.; Racz, R. R.; Hanna, M.; Obaid, A.; Angle, M. R.; Wray, W.; Kong, Y.; Hierlemann, A.; Muller, J.; Melosh, N. A.; Schaefer, A. T. 10.1101/570069 — neuroscience — Posted on 2019-03-08 2490 Genomic changes underlying host specialization in the bee gut symbiont Lactobacillus Firm5 Ellegaard, K. M.; Brochet, S.; Bonilla-Rosso, G.; Emery, O.; Glover, N.; Hadadi, N.; Jaron, K. S.; van der Meer, J. R.; Robinson-Rechavi, M.; Sentchilo, V.; Tagini, F.; SAGE class 2016-17, ; Engel, P. 10.1101/483685 — microbiology — Posted on 2019-03-08 2491 Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy and the host’s genotype upon microbiome composition Yin, J.; Sternes, P. R.; Wang, M.; Morrison, M.; Song, J.; Li, T.; Zhou, L.; Wu, X.; He, F.; Zhu, J.; Brown, M. A.; Xu, H. 10.1101/571430 — microbiology — Posted on 2019-03-08 2492 Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data Nordström, K.; Schmidt, F.; Gasparoni, N.; Salhab, A.; Gasparoni, G.; Kattler, K.; Müller, F.; Ebert, P.; Costa, I. G.; DEEP consortium, ; Pfeifer, N.; Lengauer, T.; Schulz, M. H.; Walter, J. 10.1101/547596 — genomics — Posted on 2019-03-08 2493 Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. Carlson, J. C.; Weeks, D. E.; Hawley, N. L.; Gao, G.; Cheng, H.; Naseri, T.; Reupena, M. S.; Deka, R.; McGarvey, S. T.; Minster, R. L. 10.1101/411546 — genetics — Posted on 2019-03-08 2494 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1 Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P. A.; Matos, J.; Geymonat, M.; Carballo, J. A. 10.1101/571083 — genetics — Posted on 2019-03-08 2495 Accurate inference of tree topologies from multiple sequence alignments using deep learning Suvorov, A.; Hochuli, J.; Schrider, D. 10.1101/559054 — evolutionary biology — Posted on 2019-03-08 2496 When sinks become sources: adaptive colonization in asexuals Lavigne, F.; Martin, G.; Anciaux, Y.; Papaix, J.; Roques, L. 10.1101/433235 — evolutionary biology — Posted on 2019-03-08 2497 Dengue after Zika: characterizing impacts of Zika emergence on endemic dengue transmission Borchering, R. K.; Huang, A.; Mier-y-Teran-Romero, L.; Rojas, D. P. P.; Rodriguez-Barraquer, I.; Katzelnick, L. C.; Martinez, S. D.; King, G. D.; Cinkovich, S. C.; Lessler, J.; Cummings, D. A. T. 10.1101/567537 — epidemiology — Posted on 2019-03-08 2498 Realized generation times: contraction and impact of infectious period, reproduction number and population size Torneri, A.; Azmon, A.; Faes, C.; Kenah, E.; Scalia Tomba, G.; Wallinga, J.; Hens, N. 10.1101/568485 — epidemiology — Posted on 2019-03-08 2499 Identification of the relative timing of infectiousness and symptom onset for outbreak control Cope, R. C.; Ross, J. V. 10.1101/571547 — epidemiology — Posted on 2019-03-08 2500 Trajectories of change after a health-education program in Japan Park, M.; Green, J.; Jung, H. S.; Park, Y. S. 10.1101/568584 — epidemiology — Posted on 2019-03-08 2501 Estimating the effect of the 2005 change in BCG policy in England: A retrospective cohort study Abbott, S.; Christensen, H.; Welton, N.; Brooks-Pollock, E. 10.1101/567511 — epidemiology — Posted on 2019-03-08 2502 Reducing RSV hospitalisation in a lower-income country by vaccinating mothers-to-be and their households Brand, S. P. C.; Munywoki, P.; Walumbe, D.; Keeling, M. J.; Nokes, D. J. 10.1101/569335 — epidemiology — Posted on 2019-03-08 2503 Correlations between stochastic endemic infection in multiple interacting subpopulations Meakin, S.; Keeling, M. 10.1101/568667 — epidemiology — Posted on 2019-03-08 2504 The rise and fall of the new variant of Chlamydia trachomatis in Sweden: mathematical modelling study Smid, J.; Althaus, C. L.; Low, N.; Unemo, M.; Herrmann, B. 10.1101/572107 — epidemiology — Posted on 2019-03-08 2505 Montastraea cavernosa corallite structure demonstrates distinct morphotypes across shallow and mesophotic depth zones in the Gulf of Mexico Studivan, M. S.; Milstein, G.; Voss, J. D. 10.1101/402636 — ecology — Posted on 2019-03-08 2506 Multiple species drive flexible lake food webs with warming Bartley, T. J.; Tunney, T. D.; Lester, N. P.; Shuter, B. J.; Hanner, R. H.; McCann, K. S. 10.1101/499400 — ecology — Posted on 2019-03-08 2507 Is the predation risk of mate-searching different between the sexes? Torsekar, V. R.; Isvaran, K.; Balakrishnan, R. 10.1101/363507 — ecology — Posted on 2019-03-08 2508 Few Effects of a 5-week Computerized Cognitive Training Program in Healthy Older Adults Rabipour, S.; Morrison, C.; Crompton, J.; Petrucelli, M.; Germano, M. d. O. G.; Popescu, A.; Davidson, P. S. R. 10.1101/570143 — clinical trials — Posted on 2019-03-08 2509 Respiration enhances TDP-43 toxicity, but TDP-43 retains some toxicity in the absence of respiration Park, S.-K.; Park, S.; Liebman, S. W. 10.1101/415893 — cell biology — Posted on 2019-03-08 2510 Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice Moreau, D.; Vacca, F.; Vossio, S.; Scott, C. C.; Colaco, A.; Paz Montoya, J.; Ferguson, C.; Damme, M.; Moniatte, M.; Parton, R. G.; Platt, F. M.; Gruenberg, J. 10.1101/416479 — cell biology — Posted on 2019-03-08 2511 Relating evolutionary selection and mutant clonal dynamics in normal epithelia Hall, M. W. J.; Jones, P. H.; Hall, B. A. 10.1101/480756 — cancer biology — Posted on 2019-03-08 2512 Reconstructing B cell receptor sequences from short-read single cell RNA-sequencing with BRAPeS Afik, S.; Raulet, G.; Yosef, N. 10.1101/389999 — bioinformatics — Posted on 2019-03-08 2513 MakeHub: Fully automated generation of UCSC Genome Browser Assembly Hubs Hoff, K. J. 10.1101/550145 — bioinformatics — Posted on 2019-03-08 2514 HABIT - a webserver for interactive T cell neoepitope discovery Martins, J.; Magalhaes, C.; Vieira, V.; Rocha, M.; Osorio, N. S. 10.1101/535716 — bioinformatics — Posted on 2019-03-08 2515 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y. 10.1101/567891 — bioinformatics — Posted on 2019-03-08 2516 MAGICACT: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data. Roopra, A. 10.1101/492744 — bioinformatics — Posted on 2019-03-08 2517 The evolution and phylodynamics of serotype A and SAT2 foot-and-mouth disease viruses in endemic regions of Africa Lycett, S. J.; Tanya, V. N.; Hall, M.; King, D.; Mazeri, S.; Mioulet, V.; Knowles, N.; Wadsworth, J.; Bachanek-Bankowska, K.; Ngwa Victor, N.; Morgan, K. L.; Bronsvoort, M. 10.1101/572198 — epidemiology — Posted on 2019-03-08 2518 A Collaborative Multi-Model Ensemble for Real-Time Influenza Season Forecasting in the U.S. Reich, N. G.; McGowan, C. J.; Yamana, T. K.; Tushar, A.; Ray, E. L.; Osthus, D.; Kandula, S.; Brooks, L. C.; Crawford-Crudell, W.; Gibson, G. C.; Moore, E.; Silva, R.; Biggerstaff, M.; Johansson, M.; Rosenfeld, R.; Shaman, J. 10.1101/566604 — epidemiology — Posted on 2019-03-08 2519 Older age at Initiation of Antiretroviral Therapy Predicts Low Bone Mineral Density in Children with perinatally-infected HIV in Zimbabwe Gregson, C. L.; Hartley, A.; Majonga, E.; Mchugh, G.; Crabtree, N.; Rukuni, R.; Bandason, T.; Mukwasi, C.; Ward, K. A.; Mujuru, H.; Ferrand, R. A. 10.1101/565143 — epidemiology — Posted on 2019-03-08 2520 Circulating Lysophosphatidylcholines, Phosphatidylcholines, Ceramides, and Sphingomyelins and Ovarian Cancer Risk: a 23-year Prospective Study Zeleznik, O. A.; Clish, C. B.; Kraft, P.; Avila-Pancheco, J.; Eliassen, A. H.; Tworoger, S. S. 10.1101/565044 — epidemiology — Posted on 2019-03-08 2521 Jag1 coordinates release from multipotency with cell fate choice in the developing pancreas Seymour, P. A.; Collin, C. A.; Jorgensen, M. C.; Imayoshi, I.; Honnens de Lichtenberg, K. H.; Kopan, R.; Kageyama, R.; Serup, P. 10.1101/336529 — developmental biology — Posted on 2019-03-08 2522 Hippocampal transcriptomic responses to cellular dissociation Harris, R. M.; Kao, H.-Y.; Alarcon, J. M.; Hofmann, H. A.; Fenton, A. 10.1101/153585 — neuroscience — Posted on 2019-03-08 2523 Healthy Ageing and Sentence Production: Disrupted Lexical Access in the Context of Intact Syntactic Planning Hardy, S. M.; Segaert, K.; Wheeldon, L. 10.1101/327304 — neuroscience — Posted on 2019-03-08 2524 Sexual isolation with and without ecological isolation in marine isopods Jaera albifrons and J. praehirsuta Ribardiere, A.; Pabion, E.; Coudret, J.; Daguin-Thiebaut, C.; Houbin, C.; Loisel, S.; Henry, S.; Broquet, T. 10.1101/260489 — evolutionary biology — Posted on 2019-03-08 2525 The NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression Francescone, R.; Barbosa Vendramini-Costa, D.; Franco-Barraza, J.; Wagner, J.; Muir, A.; Lau, A. N.; Gabitova, L.; Pazina, T.; Gupta, S.; Luong, T.; Shah, N.; Rollins, D.; Malik, R.; Thapa, R.; Restifo, D.; Zhou, Y.; Cai, K. Q.; Hensley, H. H.; Tan, Y.; Kruger, W. D.; Devarajan, K.; Balachandran, S.; El-Deiry, W. S.; Vander Heiden, M. G.; Peri, S.; Campbell, K. S.; Astsaturov, I.; Cukierman, E. 10.1101/330209 — cancer biology — Posted on 2019-03-08 2526 Bioinformatics analysis for L polymerase homology of arenaviruses Alrashedi, H.; Jones, I.; Mulley, G.; Neuman, B. 10.1101/178012 — bioinformatics — Posted on 2019-03-08 2527 Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949 Lind, S.; Sundqvist, M.; Holmdahl, R.; Dahlgren, C.; Forsman, H.; Olofsson, P. 10.1101/571604 — pharmacology and toxicology — Posted on 2019-03-08 2528 Fast dose fractionation using ultra-short laser accelerated proton pulses can increase cancer cell mortality, which relies on functional PARP1 protein Bayart, E.; Flacco, A.; Delmas, O.; Pommarel, L.; Levy, D.; Cavallone, M.; Megnin-Chanet, F.; Deutsch, E.; Malka, V. 10.1101/571703 — cancer biology — Posted on 2019-03-08 2529 Bioelectrical signaling via domain wall migration McNamara, H. M.; Salegame, R.; Al Tanoury, Z.; Xu, H.; Begum, S.; Ortiz, G.; Pourquie, O.; Cohen, A. E. 10.1101/570440 — biophysics — Posted on 2019-03-08 2530 Microsecond Molecular Dynamics Simulations of Diphtheria Toxin Translocation T-Domain pH-Dependent Unfolding in Solution Flores-Canales, J. C.; Simakov, N. A.; Kurnikova, M. G. 10.1101/572040 — biophysics — Posted on 2019-03-08 2531 Mechanical stress compromises multicomponent efflux complexes in bacteria Genova, L. A.; Roberts, M. F.; Wong, Y.-C.; Harper, C. E.; Santiago, A. G.; Fu, B.; Srivastava, A.; Jung, W.; Wang, L. M.; Krzeminski, Łukasz; Mao, X.; Sun, X.; Hui, C.-Y.; Chen, P.; Hernandez, C. 10.1101/571398 — biophysics — Posted on 2019-03-08 2532 Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the global transcriptional regulator Lsr2 Alqaseer, K.; Turapov, O.; Barthe, P.; Jagatia, H.; Visch, A. d.; Roumestand, C.; Wegrzyn, M.; Bartek, I. L.; Voskuil, M. I.; O'Hare, H.; Witney, A. A.; Cohen-Gonsaud, M.; Waddell, S. J.; Mukamolova, G. V. 10.1101/571406 — microbiology — Posted on 2019-03-08 2533 The level of specialization of Phytophthora infestans to potato and tomato is a biotrophy-related, stable trait Kröner, A.; Mabon, R.; Corbiere, R.; Montarry, J.; Andrivon, D. 10.1101/571596 — evolutionary biology — Posted on 2019-03-08 2534 Expression patterns of PD-L1 and PD-1 provide rationales for immune checkpoint inhibition in soft tissue sarcomas Orth, M. F.; Buecklein, V. L.; Kampmann, E.; Subklewe, M.; Noessner, E.; Cidre-Aranaz, F.; Romero-Perez, L.; Wehweck, F. S.; Lindner, L.; Issels, R.; Kirchner, T.; Altendorf-Hofmann, A.; Grunewald, T. G. P.; Knoesel, T. 10.1101/569418 — cancer biology — Posted on 2019-03-08 2535 Intrinsically disordered nuclear pore proteins show ideal-polymer morphologies and dynamics Davis, L. K.; Ford, I. J.; Saric, A.; Hoogenboom, B. 10.1101/571687 — biophysics — Posted on 2019-03-08 2536 Electrospray Surface Charge Describes Protein Molecular Motion Chalk, R.; Borkowska, O.; Azeez, K. A.; Oerum, S.; Born, P.; Gileadi, O.; Burgess-Brown, N. 10.1101/571091 — biophysics — Posted on 2019-03-08 2537 An evolutionary-conserved redox regulatory mechanism in human Ser/Thr protein kinases Byrne, D. P.; Shrestha, S.; Kannan, N.; Eyers, P. 10.1101/571844 — biochemistry — Posted on 2019-03-08 2538 Challenges and Strategies for Recruiting Type 1 Diabetes Families in Kuwait with Strong Beliefs in Familism Jahromi, M.; Rahma, Z.; Taha, N.; Abdullah, H.; Abraham, S.; Alhubail, A.; Al Sanae, H.; Aljaser, F.; Al Mahdi, M.; AbdulRasoul, M.; Al Khuwari, M. 10.1101/570945 — scientific communication and education — Posted on 2019-03-08 2539 A novel Ca2+-binding protein influences photosynthetic electron transport in Anabaena sp. PCC 7120 Walter, J.; Selim, K. A.; Leganes, F.; Fernandez-Pinas, F.; Vothknecht, U. C.; Forchhammer, K.; Aro, E.-M.; Gollan, P. J. 10.1101/571836 — plant biology — Posted on 2019-03-08 2540 Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution Garcia-Campos, M. A.; Edelheit, S.; Toth, U.; Shachar, R.; Nir, R.; Lasman, L.; Brandis, A.; Hanna, J. H.; Rossmanith, W.; Schwartz, S. 10.1101/571679 — molecular biology — Posted on 2019-03-08 2541 Prevention of enteric bacterial infections and modulation of gut microbiota composition with conjugated linoleic acids producing Lactobacillus in mice Peng, M.; Tabashsum, Z.; Patel, P.; Bernhardt, C.; Biswas, C.; Meng, J.; Biswas, D. 10.1101/571117 — microbiology — Posted on 2019-03-08 2542 QUALITY OF LIFE, SALIVARY CORTISOL AND ATOPIC DISEASES IN YOUNG CHILDREN Rolfsjord, L. B.; Skjerven, H. O.; Bakkeheim, E.; Berents, T. L.; Carlsen, K.-H.; Carlsen, K. C. L. 10.1101/570960 — immunology — Posted on 2019-03-08 2543 Genomic analysis reveals shared genes and pathways in human and canine angiosarcoma Megquier, K.; Turner-Maier, J.; Swofford, R.; Kim, J.-H.; Sarver, A. L.; Wang, C.; Sakthikumar, S.; Johnson, J.; Koltookian, M.; Lewellen, M.; Scott, M. C.; Graef, A. J.; Borst, L.; Tonomura, N.; Alfoldi, J.; Painter, C.; Thomas, R.; Karlsson, E. K.; Breen, M.; Modiano, J. F.; Elvers, I.; Lindblad-Toh, K. 10.1101/570879 — genomics — Posted on 2019-03-08 2544 The exhaustive genomic scan approach, with an application to rare-variant association analysis Kanoungi, G.; Nothnagel, M.; Becker, T.; Drichel, D. 10.1101/571752 — genetics — Posted on 2019-03-08 2545 Fertility intentions and influential factors in Dalian urban city ---A cross-sectional study based on Universal Two-child policy in China Qiu, H.; zhang, Q.; Zhang, J.; Ren, Y.; Zhou, X.; Li, S.; Liang, H.; Luo, J.; wang, Q.; hou, L. 10.1101/572008 — epidemiology — Posted on 2019-03-08 2546 Mortality among adults living with HIV treated for tuberculosis based on positive, negative, or no bacteriologic test results for tuberculosis: the IeDEA consortium Humphrey, J. M.; Mpofu, P.; Pettit, A. C.; Musick, B.; Carter, E. J.; Messou, E.; Marcy, O.; Crabtree-Ramirez, B.; Yotebieng, M.; Anastos, K.; Sterling, T. R.; Yiannoutsos, C.; Diero, L.; Wools-Kaloustian, K.; See S8 Table, 10.1101/571000 — epidemiology — Posted on 2019-03-08 2547 β-Catenin tumour-suppressor activity depends on its ability to promote Pro-N-Cadherin maturation Herrera, A.; Menendez, A.; Torroba, B.; Pons, S. 10.1101/571810 — cell biology — Posted on 2019-03-08 2548 ERK2 phosphorylates the epigenetic regulator CXXC-finger protein 1 (Cfp1) Karra, A. S.; Klein, A. M.; Earnest, S.; Stippec, S.; Wichaidit, C.; McGlynn, K.; Trudgian, D. C.; Mirzaei, H.; Cobb, M. H. 10.1101/562173 — cell biology — Posted on 2019-03-08 2549 Quantitative high-throughput tests of ubiquitous RNA secondary structure prediction algorithms via RNA/protein binding Becker, W. R.; Jarmoskaite, I.; Kappel, K.; Vaidyanathan, P. P.; Denny, S. K.; Das, R.; Greenleaf, W. J.; Herschlag, D. 10.1101/571588 — biophysics — Posted on 2019-03-08 2550 Double UP: efficient in utero electroporation via internal controls Taylor, R. J.; Carrington, J.; Taylor, K. L.; Richters, K. E.; Gerlach, L. R.; Dent, E. W. 10.1101/571323 — neuroscience — Posted on 2019-03-08 2551 Salmonella Typhi survives in human macrophages by neutralizing the RAB32/BLOC-3 host-defence pathway Baldassarre, M.; Solano-Collado, V.; Balci, A.; Wilson, H. M.; Mukhopadhyay, S.; Dougan, G.; Spano, S. 10.1101/570531 — microbiology — Posted on 2019-03-08 2552 Distinct matrix composition and mechanics in aged and estrogen-deficient mouse skin Saville, C. R.; Mallikarjun, V.; Holmes, D. F.; Emmerson, E.; Derby, B.; Swift, J.; Sherratt, M. J.; Hardman, M. J. 10.1101/570481 — biophysics — Posted on 2019-03-08 2553 PESCA: A scalable platform for the development of cell-type-specific viral drivers Hrvatin, S.; Tzeng, C. P.; Nagy, M. A.; Stroud, H.; Koutsioumpa, C.; Wilcox, O. F.; Griffith, E. C.; Greenberg, M. E. 10.1101/570895 — neuroscience — Posted on 2019-03-08 2554 NOD2 and TLR2 Signal via TBK1 and PI31 to Direct Cross-presentation and CD8 T Cell Responses Corridoni, D.; Shiraishi, S.; Chapman, T.; Steevels, T.; Muraro, D.; Thezenas, M.-L.; Prota, G.; Chen, J.-L.; Gileadi, U.; Ternette, N.; Cerundolo, V.; Simmons, A. 10.1101/570705 — immunology — Posted on 2019-03-08 2555 GCNA preserves genome integrity and fertility across species Bhargava, V.; Goldstein, C. D.; Russell, L.; Xu, L.; Ahmed, M.; Li, W.; Casey, A.; Servage, K.; Kollipara, R.; Picciarelli, Z.; Kittler, R.; Yatsenko, A.; Carmell, M.; Orth, K.; Amatruda, J. F.; Yanowitz, J. L.; Buszczak, M. 10.1101/570804 — developmental biology — Posted on 2019-03-08 2556 Frontal cortex tracks surprise separately for different sensory modalities but engages a common inhibitory control mechanism Wessel, J. R.; Huber, D. E. 10.1101/572081 — neuroscience — Posted on 2019-03-08 2557 A tertiary structure protein model for the ab-initio interpretation of small angle X-ray scattering data Prior, C.; Davies, O.; Pohl, E. 10.1101/572057 — molecular biology — Posted on 2019-03-08 2558 The Gag Protein PEG10 Binds to RNA and Regulates Trophoblast Stem Cell Lineage Specification. Abed, M.; Verschueren, E.; Budayeva, H.; Liu, P.; Kirkpatrick, D.; Reja, R.; Kummerfeld, S.; Webster, J.; Gierke, S.; Reichelt, M.; Anderson, K.; Newman, R.; Roose-Girma, M.; Modrusan, Z.; Pektas, H.; Maltepe, E.; Newton, K.; Dixit, V. 10.1101/572016 — molecular biology — Posted on 2019-03-08 2559 Iron nanoparticle-labeled murine mesenchymal stromal cells in an osteoarthritic model persists and demonstrates anti-inflammatory mechanism of action Hamilton, A. M.; Cheung, W.-Y.; Gomez-Aristizabal, A.; Nakamura, S.; Chaboureau, A.; Bhatt, S.; Sharma, A.; Kapoor, M.; Foster, P. J.; Viswanathan, S. 10.1101/571976 — cell biology — Posted on 2019-03-08 2560 Colony entropy - Allocation of goods in ant colonies Greenwald, E.; Eckmann, J.-P.; Feinerman, O. 10.1101/572032 — animal behavior and cognition — Posted on 2019-03-08 2561 Effects of estrogen on Survival and Neuronal Differentiation of adult human olfactory bulb neural stem Cells Transplanted into Spinal Cord Injured Rats Marei, H. E.; Althani, A.; Abd-Elmaksoud, A.; Kassab, M.; Farag, A.; Lashen, S.; Cenciarelli, C.; Caceci, T.; Rezk, S. 10.1101/571950 — neuroscience — Posted on 2019-03-08 2562 Effect of topical soluble epoxide hydrolase inhibition in a preclinical diabetic wound healing model. Reisdorf, W.; Rajpal, N.; Gehman, A.; Jain, P.; Burgert, M.; Sonti, S.; Agarwal, P.; Rajpal, D. 10.1101/571984 — physiology — Posted on 2019-03-08 2563 Mutations in pmrB confer cross-resistance to the LptD inhibitor POL7080 and colistin in Pseudomonas aeruginosa Romano, K. P.; Warrier, T.; Poulsen, B. E.; Nguyen, P. H.; Loftis, A. R.; Saebi, A.; Pentelute, B. L.; Hung, D. T. 10.1101/571224 — microbiology — Posted on 2019-03-08 2564 Autologous adipose-derived stem cell transplantation enhances healing of wound with exposed bone in a rat model Hamada, T.; Matsubara, H.; Yoshida, Y.; Ugaji, S.; Nomura, I.; Tsuchiya, H. 10.1101/571968 — animal behavior and cognition — Posted on 2019-03-08 2565 Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy and the host’s genotype upon microbiome composition Yin, J.; Sternes, P. R.; Wang, M.; Morrison, M.; Song, J.; Li, T.; Zhou, L.; Wu, X.; He, F.; Zhu, J.; Brown, M. A.; Xu, H. 10.1101/571430 — microbiology — Posted on 2019-03-08 2566 Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation. Hosmillo, M.; Lu, J.; McAllaster, M. R.; Eaglesham, J. B.; Wang, X.; Emmott, E.; Domingues, P.; Chaudhry, Y.; Fitzmaurice, T. J.; Tung, M. K. H.; Panas, M.; McInerney, G.; Locker, N.; Willen, C. B.; Goodfellow, I. 10.1101/571455 — microbiology — Posted on 2019-03-08 2567 Identification of bacteria involved in the decomposition of lignocellulosic biomass treated with cow rumen fluid by metagenomic analysis Lee, C. G.; Baba, Y.; Asano, R.; Fukuda, Y.; Tada, C.; Nakai, Y. 10.1101/570374 — microbiology — Posted on 2019-03-08 2568 Chromosomal barcoding of E. coli populations reveals lineage diversity dynamics at high resolution Lerner, J.; Manhart, M.; Jasinska, W.; Gauthier, L.; Serohijos, A. W. R.; Bershtein, S. 10.1101/571505 — evolutionary biology — Posted on 2019-03-08 2569 Analysis of genomic loci harboring 59,732 human-specific regulatory sequences reveals unique to human regulatory patterns associated with brain development Glinsky, G. 10.1101/432625 — genomics — Posted on 2019-03-08 2570 Nuclear Genome Size is Positively Correlated with Mean LTR Insertion Date in Fern and Lycophyte Genomes Baniaga, A.; Barker, M. S. 10.1101/571570 — evolutionary biology — Posted on 2019-03-08 2571 NetrinG1/NGL-1 Axis promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional supply and immunosuppression Francescone, R.; Barbosa Vendramini-Costa, D.; Franco-Barraza, J.; Wagner, J.; Muir, A.; Lau, A. N.; Gabitova, L.; Pazina, T.; Gupta, S.; Luong, T.; Shah, N.; Rollins, D.; Malik, R.; Thapa, R.; Restifo, D.; Zhou, Y.; Cai, K. Q.; Hensley, H. H.; Tan, Y.; Kruger, W. D.; Devarajan, K.; Balachandran, S.; El-Deiry, W. S.; Vander Heiden, M. G.; Peri, S.; Campbell, K. S.; Astsaturov, I.; Cukierman, E. 10.1101/330209 — cancer biology — Posted on 2019-03-08 2572 Reorientation and propulsion in fast-starting zebrafish larvae: an inverse dynamics analysis Voesenek, C. J.; Pieters, R. P. M.; Muijres, F. T.; van Leeuwen, J. L. 10.1101/570812 — biophysics — Posted on 2019-03-08 2573 A simplified analytical model of sound propagationin the human ear Gambin, W. L. 10.1101/571034 — bioengineering — Posted on 2019-03-08 2574 In vivo glucose imaging in multiple model organisms with an engineered single-wavelength sensor Keller, J. P.; Marvin, J. S.; Lacin, H.; Lemon, W. C.; Shea, J.; Kim, S.; Lee, R. T.; Koyama, M.; Keller, P. J.; Looger, L. 10.1101/571422 — bioengineering — Posted on 2019-03-08 2575 Repositioning septins within the core particle Mendonca, D. C.; Macedo, J. N.; Itri, R.; Guimaraes, S. L.; Barroso da Silva, F. L.; Cassago, A.; Garratt, R. C.; Portugal, R.; Araujo, A. P. 10.1101/569251 — biochemistry — Posted on 2019-03-08 2576 KLK4 inhibition by cyclic and acyclic peptides: structural and dynamical insights into standard-mechanism protease inhibitors Riley, B. T.; Ilyichova, O.; de Veer, S.; swedberg, J.; Wilson, E.; Hoke, D. E.; Harris, J.; Buckle, A. 10.1101/570390 — biochemistry — Posted on 2019-03-08 2577 Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group Crysnanto, D.; Obbard, D. 10.1101/429894 — evolutionary biology — Posted on 2019-03-07 2578 Prevalence, phenotype and architecture of developmental disorders caused by de novo mutation McRae, J. F.; Clayton, S.; Fitzgerald, T. W.; Kaplanis, J.; Prigmore, E.; Rajan, D.; Sifrim, A.; Aitken, S.; Akawi, N.; Alvi, M.; Ambridge, K.; Barrett, D. M.; Bayzetinova, T.; Jones, P.; Jones, W. D.; King, D.; Krishnappa, N.; Mason, L. E.; Singh, T.; Tivey, A. R.; Ahmed, M.; Anjum, U.; Archer, H.; Armstrong, R.; Awada, J.; Balasubramanian, M.; Banka, S.; Baralle, D.; Barnicoat, A.; Batstone, P.; Baty, D.; Bennett, C.; Berg, J.; Bernhard, B.; Bevan, A. P.; Bitner-Glindzicz, M.; Blair, E.; Blyth, M.; Bohanna, D.; Bourdon, L.; Bourn, D.; Bradley, L.; Brady, A.; Brent, S.; Brewer, C.; Brunstrom, 10.1101/049056 — genetics — Posted on 2019-03-07 2579 Integrin binding dynamics modulate ligand-specific mechanosensing in mammary gland fibroblasts Lerche, M.; Elosegui-Artola, A.; Guzman, C.; Georgiadou, M.; Kechagia, J. Z.; Gulberg, D.; Roca-Cusachs, P.; Peuhu, E.; Ivaska, J. 10.1101/570721 — cell biology — Posted on 2019-03-07 2580 A gravity-based three-dimensional compass in the mouse brain Angelaki, D.; Ng, J.; Abrego, A. M.; Cham, H. X.; Dickman, D.; Laurens, J. 10.1101/570382 — neuroscience — Posted on 2019-03-07 2581 Nanopore sequencing for fast determination of plasmids, phages, virulence markers, and antimicrobial resistance genes in Shiga toxin-producing Escherichia coli Gonzalez-Escalona, N.; Allard, M. W.; Brown, E.; Sharma, S.; Hoffmann, M. 10.1101/571364 — genomics — Posted on 2019-03-07 2582 Fenestrae-associated protein Plvap regulates the rate of blood-borne proteins passage into the hypophysis Gordon, L.; Blechman, J.; Shimoni, E.; Gur, D.; Anand-Apte, B.; Levkowitz, G. 10.1101/571299 — developmental biology — Posted on 2019-03-07 2583 A Clustering Approach for Detecting Implausible Observation Values in Electronic Health Records Data Estiri, H.; Murphy, S. N. 10.1101/570564 — bioinformatics — Posted on 2019-03-07 2584 μECoG Recordings Through a Thinned Skull Brodnick, S. K.; Ness, J. P.; Richner, T. J.; Thongpang, S.; Novello, J.; Hayat, M.; Cheng, K. P.; Krugner-Higby, L.; Suminski, A. J.; Ludwig, K. A.; Williams, J. C. 10.1101/564146 — neuroscience — Posted on 2019-03-07 2585 Systematic evaluation and validation of reference and library selection methods for deconvolution of cord blood DNA methylation data Gervin, K.; Salas, L. A.; Bakulski, K. M.; van Zelm, M. C.; Koestler, D. C.; Wiencke, J. K.; Duijts, L.; Moll, H. A.; Kelsey, K. T.; Kobor, M. S.; Lyle, R.; Christensen, B. C.; Felix, J.; Jones, M. J. 10.1101/570457 — bioinformatics — Posted on 2019-03-07 2586 A novel structure-based control method for controlling complex large scale nonlinear dynamical networks Guo, W.-F.; Zhang, S.-W.; Zeng, T.; Li, Y.; Gao, J.; Chen, L. 10.1101/503565 — systems biology — Posted on 2019-03-07 2587 Genetic determinants of gut microbiota composition and bile acid profiles in mice Kemis, J. H.; Linke, V.; Barrett, K. L.; Boehm, F. J.; Traeger, L. L.; Keller, M. P.; Rabaglia, M. E.; Schueler, K. L.; Stapleton, D. S.; Gatti, D. M.; Churchill, G. A.; Amador-Noguez, D.; Russell, J. D.; Yandell, B. S.; Broman, K. W.; Coon, J. J.; Attie, A. D.; Rey, F. E. 10.1101/571075 — systems biology — Posted on 2019-03-07 2588 Native protein delivery into rice callus using ionic complexes of protein and cell-penetrating peptides Guo, B.; Itami, J.; Oikawa, K.; Motoda, Y.; Kigawa, T.; Numata, K. 10.1101/570853 — plant biology — Posted on 2019-03-07 2589 A high-throughput delayed fluorescence method reveals underling differences in the control of circadian rhythms in Triticum aestivum and Brassica napus Rees, H.; Duncan, S.; Gould, P.; Wells, R.; Greenwood, M.; Brabbs, T.; Hall, A. 10.1101/570572 — plant biology — Posted on 2019-03-07 2590 Comparison between proton magnetic resonance spectroscopy and high-performance liquid chromatography to quantify muscle carnosine in humans Silva, V. d. E.; Painelli, V. d. S.; Shinjo, S. K.; Cilli, E. M.; Sale, C.; Gualano, B.; Otaduy, M. C.; Artioli, G. G. 10.1101/568923 — physiology — Posted on 2019-03-07 2591 Spontaneous network activity <35 Hz accounts for variability in stimulus-induced gamma responses Hirschmann, J.; Baillet, S.; Schnitzler, A.; Woolrich, M.; Vidaurre, D.; Florin, E. 10.1101/381236 — neuroscience — Posted on 2019-03-07 2592 N-glycosylation of the protein disulfide isomerase Pdi1 ensures Ustilago maydis virulence Marin-Menguiano, M.; Moreno-Sanchez, I.; Barrales, R. R.; Fernandez-Alvarez, A.; Ibeas, J. I. 10.1101/571125 — microbiology — Posted on 2019-03-07 2593 Leishmania major degrades murine CXCL1 - an immune evasion strategy Yorek, M. S.; Poudel, B.; Mazgaeen, L.; Pope, R. M.; Wilson, M. E.; Gurung, P. 10.1101/571141 — microbiology — Posted on 2019-03-07 2594 The Genomic Landscape of Centromeres in Cancers Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R. 10.1101/505800 — genomics — Posted on 2019-03-07 2595 Reduced chromatin accessibility underlies gene expression differences in homologous chromosome arms of hexaploid wheat and diploid Aegilops tauschii Lu, F.-H.; McKenzie, N.; Gardiner, L.-J.; Luo, M.; Hall, A.; Bevan, M. W. 10.1101/571133 — genomics — Posted on 2019-03-07 2596 Epistasis detectably alters correlations between genomic sites in a narrow parameter window Pedruzzi, G.; Rouzine, I. M. 10.1101/570903 — genetics — Posted on 2019-03-07 2597 Cohesin and microtubule dependent mechanisms regulate sister centromere fusion during meiosis I McKim, K. S.; Wang, L.-I.; Das, A. 10.1101/571067 — genetics — Posted on 2019-03-07 2598 Cdc14 phosphatase ensures resolution of aberrant meiotic recombination outcomes partly through activating Yen1/GEN1 Pascual-Silva, C.; Strouhalova, K.; Garside, G. B.; Arter, M.; Alvarez-Melo, D.; Bermejo, T.; San-Segundo, P. A.; Matos, J.; Geymonat, M.; Carballo, J. A. 10.1101/571083 — genetics — Posted on 2019-03-07 2599 Generation of a white-albino phenotype from cobalt blue and yellow-albino trouts: inheritance pattern and chromatophores analysis Hattori, R. S.; Yoshinaga, T. T.; Butzge, A. J.; Hattori-Ihara, S.; Tsukamoto, R. Y.; Takahashi, N. S.; Tabata, Y. A. 10.1101/570861 — genetics — Posted on 2019-03-07 2600 A Bayesian method using sparse data to estimate penetrance of disease-associated genetic variants Kroncke, B.; Smith, D.; Glazer, A. M.; Roden, D. M.; Blume, J. D. 10.1101/571158 — genetics — Posted on 2019-03-07 2601 Direct inference of the distribution of fitness effects of spontaneous mutations in Chlamydomonas reinhardtii Keightley, P. D.; Boendel, K.; Kraemer, S.; Samuels, T.; McClean, D.; Lachapelle, J.; Ness, R.; Colegrave, N. 10.1101/571018 — evolutionary biology — Posted on 2019-03-07 2602 An ancient lineage of highly divergent parvoviruses infects both vertebrate and invertebrate hosts. Gifford, R. J.; Agbandje-McKenna, M.; de Souza, W. M.; Penzes, J. 10.1101/571109 — evolutionary biology — Posted on 2019-03-07 2603 Signatures of Environmental Adaptation During Range Expansion of Wild Common Bean (Phaseolus vulgaris) Ariani, A.; Gepts, P. 10.1101/571042 — ecology — Posted on 2019-03-07 2604 Nijmegen Breakage Syndrome (NBS) is a telomeropathy: analysis of telomere length in NBS homo- and heterozygotes and humanized Nbs ice Habib, R.; Kim, R.; Neitzel, H.; Demuth, I.; Chrzanowska, K.; Seemanova, E.; Faber, R.; Digweed, M.; Jäger, K.; Sperling, K.; Walter, M. 10.1101/571026 — cancer biology — Posted on 2019-03-07 2605 Long-lasting effects of proanthocyanidins in rat prevent cafeteria diet effects by limiting adipose tissue accrual Ardevol, A.; Gines, I.; GIL-CARDOSO, K.; Serrano, J.; CASANOVA-MARTI, A.; Lobato, M.; Terra, X.; Blay, M.; Pinent, M. 10.1101/570994 — biochemistry — Posted on 2019-03-07 2606 Mapping Lung Cancer Epithelial-Mesenchymal Transition States and Trajectories with Single-Cell Resolution Karacosta, L. G.; Anchang, B.; Ignatiadis, N.; Kimmey, S. C.; Benson, J. A.; Shrager, J. B.; Tibshirani, R.; Bendall, S. C.; Plevritis, S. K. 10.1101/570341 — systems biology — Posted on 2019-03-07 2607 Genotype-free demultiplexing of pooled single-cell RNA-seq Xu, J.; Falconer, C.; Coin, L. 10.1101/570614 — bioinformatics — Posted on 2019-03-07 2608 Acute regulation of habituation learning via posttranslational palmitoylation Nelson, J. C.; Witze, E.; Ma, Z.; Ciocco, F.; Frerotte, A.; Foskett, J. K.; Granato, M. 10.1101/570044 — neuroscience — Posted on 2019-03-07 2609 Reduced Default Mode Network Functional Connectivity in Patients with Recurrent Major Depressive Disorder Yan, C.-G.; Chen, X.; Li, L.; Castellanos, F. X.; Bai, T.-J.; Bo, Q.-J.; Chen, G.-M.; Chen, N.-X.; Chen, W.; Cheng, C.; Cheng, Y.-Q.; Cui, X.-L.; Duan, J.; Fang, Y.-R.; Gong, Q.-Y.; Guo, W.-B.; Hou, Z.-H.; Hu, L.; Kuang, L.; Li, F.; Li, K.-M.; Li, T.; Liu, Y.-S.; Liu, Z.-N.; Long, Y.-C.; Luo, Q.-H.; Meng, H.-Q.; Peng, D.-H.; Qiu, H.-T.; Qiu, J.; Shen, Y.-D.; Shi, Y.-S.; Si, T.-M.; Wang, C.-Y.; Wang, F.; Wang, K.; Wang, L.; Wang, X.; Wang, Y.; Wu, X.-P.; Wu, X.-R.; Xie, C.-M.; Xie, G.-R.; Xie, H.-Y.; Xie, P.; Xu, X.-F.; Yang, H.; Yang, J.; Yao, J.-S.; Yao, S.-Q.; Yin, Y.-Y.; Yuan, Y.-G.; Zhang, 10.1101/321745 — neuroscience — Posted on 2019-03-07 2610 Brain Age Prediction: Cortical and Subcortical Shape Covariation in the Developing Human Brain Zhao, Y.; Klein, A.; Castellanos, F.; Milham, M. P. 10.1101/570333 — neuroscience — Posted on 2019-03-07 2611 Manure substitution of chemical fertilizer affect soil microbial community diversity, structure and function in greenhouse vegetable production systems Luan, H.; Gao, W.; Huang, S.; Tang, J.; Li, M.; Zhang, H.; Chen, X. 10.1101/570986 — microbiology — Posted on 2019-03-07 2612 Identification and characterization of putative Aeromonas spp. T3SS effectors Rangel, L. T.; Marden, J.; Colston, S.; Setubal, J. C.; Graf, J.; Gogarten, J. P. 10.1101/570887 — microbiology — Posted on 2019-03-07 2613 Hybrid assembly of the genome of the entomopathogenic nematode Steinernema carpocapsae identifies the X-chromosome Mortazavi, A.; Macchietto, M.; Serra, L.; Macias-Munoz, A.; McGill, C. J.; Rodriguez, I. M.; Rodriguez, B.; Murad, R. 10.1101/571265 — genomics — Posted on 2019-03-07 2614 Mapping Histone Modifications in Low Cell Number and Single Cells Using Antibody-guided Chromatin Tagmentation (ACT-seq) Carter, B.; Ku, W. L.; Tang, Q.; Zhao, K. 10.1101/571208 — genomics — Posted on 2019-03-07 2615 Identification of differentially expressed genes in hepatocellular carcinoma by integrated bioinformatic analysis Yan, G.; Liu, Z. 10.1101/570846 — genetics — Posted on 2019-03-07 2616 Changes in the Physicochemical Properties and Microbial Communities of Rhizospheric Soil after Cassava/Peanut Intercropping Tang, X.; Luo, S.; Huang, Z.; Wu, H.; Wang, J.; Shi, G.; He, L.; Xiong, F.; Jiang, J.; Liu, J.; Liao, G.; Tang, R.; He, L. 10.1101/570937 — ecology — Posted on 2019-03-07 2617 Interkinetic nuclear migration in the zebrafish retina as a diffusive process Azizi, A.; Herrmann, A.; Wan, Y.; Buse, S. J.; Keller, P.; Goldstein, R. E.; Harris, W. A. 10.1101/570606 — developmental biology — Posted on 2019-03-07 2618 GCNA interacts with Spartan and Topoisomerase II to regulate genome stability. Davis, G. M.; Dokshin, G.; Sawle, A. D.; Eldridge, M. D.; Romer, K. A.; Gourley, T. E.; Molesworth, L. W.; Tatnell, H. R.; Ozturk, A. R.; de Rooij, D. G.; Hannon, G. J.; Page, D. C.; Mello, C. C.; Carmell, M. A. 10.1101/570200 — developmental biology — Posted on 2019-03-07 2619 A weak Foxp3 hypomorph enhances spontaneous and therapeutic immune surveillance of cancer in mice Almeida-Santos, J.; Bergman, M.-L.; Cabral, I. A.; Correia, V.; Caramalho, I.; Demengeot, J. 10.1101/570671 — cancer biology — Posted on 2019-03-07 2620 Cdc42EP5/BORG3 coordinates septin and actin networks to promote actomyosin function and melanoma invasion and metastasis Farrugia, A. J.; Orgaz, J. L.; Sanz-Moreno, V.; Calvo, F. 10.1101/570747 — cancer biology — Posted on 2019-03-07 2621 Effect of Saudi and Egyptian pomegranate polyphenols in regulating the activity of PON1, PON2 and lipid profile for preventing coronary heart disease BinMowyna, M. N.; Binobead, M. A.; Al Badr, N. A.; AlSedairy, S. A.; Elredh, I. A. R.; Al-Qahtani, W. S. 10.1101/570838 — biochemistry — Posted on 2019-03-07 2622 An abscisic acid (ABA) homeostasis regulated by its production, catabolism and transport in peanut leaves in response to drought stress Long, H.; Zheng, Z.; Zhang, Y.; Xing, P.; Wan, X.; Zheng, Y.; Li, L. 10.1101/569848 — plant biology — Posted on 2019-03-07 2623 Approach for Semi-Automated Measurement of Fiber Diameter in Murine and Canine Skeletal Muscle Stevens, C. R.; Sledziona, M.; Moore, T.; Dong, L.; Cheetham, J. 10.1101/569780 — neuroscience — Posted on 2019-03-07 2624 Diffusion Tensor Tractography of Brainstem Fibers and Its Application in Pain Zhang, Y.; Vakhtin, A. A.; Jennings, J. S.; Massaband, P.; Wintermark, M.; Craig, P. L.; Ashford, J. W.; Clark, D. J.; Furst, A. J. 10.1101/569723 — neuroscience — Posted on 2019-03-07 2625 Sterol-O acyltransferase 1 is inhibited by gga-miR-181a-5p and gga-miR-429-3p through the TGFβ pathway in endodermal epithelial cells of Japanese quail Lin, H.-J.; Lin, C.-W.; Mersmann, H. J.; Ding, S.-T. 10.1101/569806 — molecular biology — Posted on 2019-03-07 2626 Mechanical, physical and chemical characterisation of mycelium-based composites with different types of lignocellulosic substrates Elsacker, E.; Vandelook, S.; Brancart, J.; Peeters, E.; De Laet, L. 10.1101/569749 — microbiology — Posted on 2019-03-07 2627 HRPK-1, a conserved KH-domain protein, modulates microRNA activity during Caenorhabditis elegans development Zinovyeva, A.; Li, L.; Veksler-Lublinsky, I. 10.1101/569905 — genetics — Posted on 2019-03-07 2628 A causal approach to understanding management factors, reproductive underperformance and reproductive infections in dairy cattle Skjerve, E.; Softic, A.; Godfroid, J.; Granquist, E.; Asmare, K.; Fejzic, N. 10.1101/569764 — epidemiology — Posted on 2019-03-07 2629 In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex which supports oogenesis Guioli, S.; Zhao, D.; Nandi, S.; Clinton, M.; Lovell-Badge, R. 10.1101/568691 — developmental biology — Posted on 2019-03-07 2630 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P. 10.1101/569319 — neuroscience — Posted on 2019-03-07 2631 Persistence of neuronal representations through time and damage in the hippocampus. Gonzalez, W. G.; Zhang, H.; Harutyunyan, A.; Lois, C. 10.1101/559104 — neuroscience — Posted on 2019-03-07 2632 Interpretable genotype-to-phenotype classifiers with performance guarantees Drouin, A.; Letarte, G.; Raymond, F.; Marchand, M.; Corbeil, J.; Laviolette, F. 10.1101/388348 — genomics — Posted on 2019-03-07 2633 The flickering connectivity system of the north Andean paramos Flantua, S. G. A.; O'Dea, A.; Onstein, R. E.; Hooghiemstra, H. 10.1101/569681 — ecology — Posted on 2019-03-07 2634 A \"Dirty\" Footprint: Anthropogenic Soils Promote Biodiversity in Amazonian Rainforests Demetrio, W. C.; Conrado, A. C.; Acioli, A.; Ferreira, A. C.; Bartz, M. L.; James, S. W.; da Silva, E.; Maia, L. S.; Martins, G. C.; Macedo, R. S.; Stanton, D. W. G.; Lavelle, P.; Velasquez, E.; Zangerle, A.; Tapia-Coral, S.; Barbosa, R.; Muniz, A. W.; Santos, A.; Ferreira, T.; Segalla, R. F.; Decaens, T.; PenaVenegas, C. P.; Nadolny, H. S.; Maia, C. S.; Pasini, A.; Motta, A. F.; Taube Junior, P. S.; Silva, T. A.; Rebellato, L.; Oliveira Junior, R. C.; Neves, E. G.; Pinto Lima, H.; Feitosa, R.; Vidal Torrado, P.; McKey, D.; Clement, C. R.; Shock, M. P.; Teixeira, W. G.; Carlos V. Motta, A.; de 10.1101/552364 — zoology — Posted on 2019-03-07 2635 A hierarchical approach to model decision making: a study in chemotactic behavior of Escherichia coli Vafadar, S.; Kavousi, K.; Safdari, H.; Kalirad, A.; Sadeghi, M. 10.1101/569277 — systems biology — Posted on 2019-03-07 2636 Whisking signals motor preparation and the behavioral state of mice Dominiak, S. E.; Nashaat, M. A.; Sehara, K.; Oraby, H.; Larkum, M. E.; Sachdev, R. N. 10.1101/568030 — neuroscience — Posted on 2019-03-07 2637 Sweet revenge - Streptococcus pyogenes showcases first example of immune evasion through specific IgG glycan hydrolysis Naegeli, A.; Bratanis, E.; Karlsson, C.; Shannon, O.; Kalluru, R.; Linder, A.; Malmström, J.; Collin, M. 10.1101/544064 — microbiology — Posted on 2019-03-07 2638 Ubiquitin-dependent and -independent roles of E3 ligase RIPLET in innate immunity Cadena, C.; Ahmad, S.; Xavier, A.; Willemsen, J.; Park, S.; Park, J. W.; Oh, S.-W.; Fujita, T.; Hou, F.; Binder, M.; Hur, S. 10.1101/367656 — immunology — Posted on 2019-03-07 2639 Differences in Genetic Liability for Insomnia and Hypersomnia in Bipolar Disorder Subtypes Lewis, K. J. S.; Richards, A.; Leonenko, G.; Jones, S. E.; Jones, H.; Gordon-Smith, K.; Forty, L.; Escott-Price, V.; Owen, M. J.; Weedon, M. N.; Jones, L.; Craddock, N.; Jones, I.; O'Donovan, M. C.; Di Florio, A. 10.1101/569376 — genomics — Posted on 2019-03-07 2640 A rapid and simple method for assessing and representing genome sequences relatedness Briand, M.; Bouzid, M.; Hunault, G.; Legeay, M.; Fischer-Le Saux, M.; Barret, M. 10.1101/569640 — genomics — Posted on 2019-03-07 2641 HiVA: an integrative wet- and dry-lab platform for haplotype and copy number analysis of single-cell genomes Zamani Esteki, M.; Ardeshirdavani, A.; Alcaide, D.; Masset, H.; Ding, J.; Sifrim, A.; Kumar, P.; Dimitriadou, E.; Aerts, J.; Voet, T.; Moreau, Y.; Vermeesch, J. R. 10.1101/564914 — genomics — Posted on 2019-03-07 2642 On the cross-population portability of gene expression prediction models Keys, K. L.; Mak, A. C. Y.; White, M. J.; Eckalbar, W.; Dahl, A. J.; Mefford, J.; Mikhaylova, A. V.; Contreras, M. G.; Elhawary, J. R.; Eng, C.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Lenoir, M. A.; Ye, C. J.; Thornton, T. A.; Zaitlen, N.; Burchard, E. G.; Gignoux, C. R. 10.1101/552042 — genomics — Posted on 2019-03-07 2643 Cleaning genotype data from Diversity Outbred mice Broman, K. W.; Gatti, D. M.; Svenson, K. L.; Sen, S.; Churchill, G. A. 10.1101/518308 — genetics — Posted on 2019-03-07 2644 Adaptation and the Parliament of Genes Scott, T. W.; West, S. A. 10.1101/526970 — evolutionary biology — Posted on 2019-03-07 2645 Environmentally-driven dynamic parameters in mechanistic movement models reveal complex migratory pacing in a soaring bird Eisaguirre, J.; Auger-Methe, M.; Barger, C.; Lewis, S.; Booms, T.; Breed, G. 10.1101/465427 — ecology — Posted on 2019-03-07 2646 A homozygous genome-edited Sept2-EGFP fibroblast cell line Banko, M.; Mucha-Kruczynska, I.; Weise, C.; Heyd, F.; Ewers, H. 10.1101/570622 — cell biology — Posted on 2019-03-07 2647 The midbody interactome reveals new unexpected roles for PP1 phosphatases in cytokinesis Capalbo, L.; Bassi, Z.; Geymonat, M.; Todesca, S.; Copoiu, L.; Enright, A.; Callaini, G.; Riparbelli, M. G.; Yu, L.; Choudhary, J.; Ferrero, E.; Wheatley, S.; Douglas, M.; Mishima, M.; D'Avino, P. P. 10.1101/569459 — cell biology — Posted on 2019-03-07 2648 Revised subunit order of mammalian septin complexes explains their in vitro polymerization properties Soroor, F.; Kim, M. S.; Palander, O.; Balachandran, Y.; Collins, R.; Benlekbir, S.; Rubinstein, J.; Trimble, W. S. 10.1101/569871 — cell biology — Posted on 2019-03-07 2649 EHD2-mediated restriction of caveolar dynamics regulates cellular lipid uptake Matthaeus, C.; Lahmann, I.; Kunz, S.; Jonas, W.; Melo, A. A.; Lehmann, M.; Larsson, E.; Lundmark, R.; Kern, M.; Blueher, M.; Hauke, V.; Mueller, D. N.; Schuermann, A.; Birchmeier, C.; Daumke, O. 10.1101/511709 — cell biology — Posted on 2019-03-07 2650 Attack and defence in cellular decision-making: lessons from machine learning Rademaker, T. J.; Bengio, E.; Francois, P. 10.1101/366724 — biophysics — Posted on 2019-03-07 2651 Energy Landscape of the Domain Movement in Staphylococcus aureus UDP-N-acetylglucosamine 2-epimerase de Azevedo, E. C.; Nascimento, A. S. 10.1101/535138 — biophysics — Posted on 2019-03-07 2652 MultiCapsNet: a interpretable deep learning classifier integrate data from multiple sources Wang, L.; Miao, X.; Zhang, J.; Cai, J. 10.1101/570507 — bioinformatics — Posted on 2019-03-07 2653 MAGICACT: A tool for predicting transcription factors and cofactors driving gene sets using ENCODE data. Roopra, A. 10.1101/492744 — bioinformatics — Posted on 2019-03-07 2654 Bacterial defiance as a form of prodrug failure Holt, B. A.; Curro, I.; Kwong, G. A. 10.1101/556951 — bioengineering — Posted on 2019-03-07 2655 Can sleep protect memories from catastrophic forgetting? Gonzalez, O. C.; Sokolov, Y.; Krishnan, G.; Bazhenov, M. 10.1101/569038 — neuroscience — Posted on 2019-03-07 2656 Extracellular vesicle-mediated RNA release in Histoplasma capsulatum Alves, L. R.; Peres da Silva, R.; Sanchez, D. A.; Zamith-Miranda, D.; Rodrigues, M. L.; Goldenberg, S.; Puccia, R.; Nosanchuk, J. D. 10.1101/570291 — microbiology — Posted on 2019-03-07 2657 A simple microbiome in the European common cuttlefish, Sepia officinalis Lutz, H. L.; Ramirez-Puebla, T.; Abbo, L.; Durand, A.; Schlundt, C.; Sjaarda, A. K.; Gottel, N.; Hanlon, R.; Gilbert, J.; Mark Welch, J. 10.1101/440677 — microbiology — Posted on 2019-03-07 2658 Experimental introgression to evaluate the impact of sex specific traits on Drosophila melanogaster incipient speciation Cortot, J.; Farine, J.-P.; Houot, B.; Everaerts, C.; Ferveur, J.-F. 10.1101/569699 — evolutionary biology — Posted on 2019-03-07 2659 Widespread gene duplication and adaptive evolution in the RNA interference pathways of the Drosophila obscura group Crysnanto, D.; Obbard, D. 10.1101/429894 — evolutionary biology — Posted on 2019-03-07 2660 Extreme midsummer rainfall event drives early onset cyanobacterial bloom Larsen, M. L.; Baulch, H. M.; Schiff, S. L.; Simon, D. F.; Sauve, S.; Venkiteswaran, J. J. 10.1101/570275 — ecology — Posted on 2019-03-07 2661 A non-canonical role of polo-like kinase-4 in adventitial fibroblast cell type transition Li, J.; Urabe, G.; Zhang, M.; Huang, Y.; Wang, B.; Marcho, L.; Shen, H.; Kent, K. C.; Guo, L.-W. 10.1101/570267 — cell biology — Posted on 2019-03-07 2662 A cancer-associated missense mutation in PP2A-Aα increases centrosome clustering during mitosis V. Antao, N.; Marcet-Ortega, M.; Cifani, P.; Kentsis, A.; A. Foley, E. 10.1101/570978 — cell biology — Posted on 2019-03-07 2663 SPARSE INFOMAX BASED ON HOYER PROJECTION AND ITS APPLICATION TO SIMULATED STRUCTURAL MRI AND SNP DATA Duan, K.; Silva, R. F.; Chen, J.; Lin, D.; Calhoun, V. D.; Liu, J. 10.1101/570317 — bioengineering — Posted on 2019-03-07 2664 Analysis of the frequency and pathogenicity of ATP7B variants in a genomic dataset: implications for Wilson disease prevalence and penetrance Wallace, D. F.; Dooley, J. S. 10.1101/499285 — genetics — Posted on 2019-03-07 2665 Temporal dynamics of inhalation-linked activity across defined subpopulations of mouse olfactory bulb neurons imaged in vivo. Short, S. M.; Wachowiak, M. 10.1101/558999 — neuroscience — Posted on 2019-03-07 2666 Use of a filter cartridge combined with intra-cartridge bead beating improves detection of microbial DNA from water samples Ushio, M. 10.1101/435305 — ecology — Posted on 2019-03-07 2667 Rapid proteotyping reveals cancer biology and drug response determinants in the NCI-60 cells Guo, T.; Luna, A.; Koh, C. C.; Rajapakse, V.; Wu, Z.; Menden, M. P.; Cheng, Y.; Calzone, L.; Martignetti, L.; Ori, A.; Iskar, M.; Gillet, L.; Zhong, Q.; Varma, S.; Schmitt, U.; Qiu, P.; Sun, Y.; zhu, Y.; Wild, P.; Mathew, G.; Bork, P.; Beck, M.; Saez-Rodriguez, J.; Reinhold, W.; Sander, C.; Pommier, Y.; Aebersold, R. 10.1101/268953 — systems biology — Posted on 2019-03-07 2668 Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C Vallianatos, C. N.; Raines, B.; Porter, R. S.; Wu, M. C.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, C. E.; Tronson, N.; Iwase, S. 10.1101/567917 — genetics — Posted on 2019-03-07 2669 A Multi-Domain Task Battery Reveals Functional Boundaries in the Human Cerebellum King, M.; Hernandez-Castillo, C. R.; Poldrack, R. A.; Ivry, R.; Diedrichsen, J. 10.1101/423509 — neuroscience — Posted on 2019-03-06 2670 Structure-Unbinding Kinetics Relationship of p38 MAPK Inhibitors Ge, X.; Tan, H.; Xie, L. 10.1101/510255 — pharmacology and toxicology — Posted on 2019-03-06 2671 Fractionation of impulsive and compulsive trans-diagnostic phenotypes and their longitudinal associations Chamberlain, S. R.; Tiego, J.; Fontenelle, L.; Hook, R.; Segrave, R.; Hauser, T.; Dolan, R.; Goodyer, I.; Bullmore, E.; Grant, J.; Yucel, M. 10.1101/570218 — neuroscience — Posted on 2019-03-06 2672 The time-course of component processes of selective attention Wen, T.; Duncan, J.; Mitchell, D. J. 10.1101/511022 — neuroscience — Posted on 2019-03-06 2673 Corrective muscle activity reveals subject-specific sensorimotor recalibration. Iturralde, P. A.; Torres-Oviedo, G. 10.1101/372359 — neuroscience — Posted on 2019-03-06 2674 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P. 10.1101/569319 — neuroscience — Posted on 2019-03-06 2675 How sample heterogeneity can obscure the signal of microbial interactions Armitage, D. W.; Jones, S. E. 10.1101/520668 — microbiology — Posted on 2019-03-06 2676 Single-cell RNA-seq reveals spatially restricted multicellular fibrotic niches during lung fibrosis Joshi, N.; Watanabe, S.; Verma, R.; Jablonski, R. P.; Chen, C.-I.; Cheresh, P.; Reyfman, P. A.; McQuattie-Pimentel, A. C.; Sichizya, L.; Flozak, A. S.; Gottardi, C. J.; Cuda, C. M.; Perlman, H.; Jain, M.; Kamp, D. W.; Budinger, G. S.; Misharin, A. V. 10.1101/569855 — immunology — Posted on 2019-03-06 2677 Bone marrow transplantation rescues monocyte recruitment defect and improves cystic fibrosis in mice Fan, Z.; Miller, J.; Herro, R.; Ehinger, E.; Conrad, D. J.; Mikulski, Z.; Zhu, Y. P.; Marcovecchio, P. M.; Hedrick, C. C.; Ley, K. 10.1101/570135 — immunology — Posted on 2019-03-06 2678 Genomic architecture of phenotypic plasticity of complex traits in tetraploid wheat in response to water stress Fatiukha, A.; Deblieck, M.; Klymiuk, V.; Merchuk-Ovnat, L.; Peleg, Z.; Ordon, F.; Fahima, T.; Korol, A. B.; Saranga, Y.; Krugman, T. 10.1101/565820 — genetics — Posted on 2019-03-06 2679 Neuropsychiatric Phenotypes in 3q29 Deletion Syndrome and Novel Features of ASD: Results from the 3q29 Registry Pollak, R. M.; Murphy, M. M.; Epstein, M. P.; Zwick, M. E.; Klaiman, C.; Saulnier, C. A.; The Emory 3q29 Project, ; Mulle, J. G. 10.1101/386243 — genetics — Posted on 2019-03-06 2680 Boosting Diabetes and Pre-Diabetes Screening in Rural Ghana Crimi, A.; Nyarko, B. E.; Amoah, R. S. 10.1101/278960 — epidemiology — Posted on 2019-03-06 2681 Vector competence for Zika virus is not affected by mosquito age but vectorial capacity of Ae. aegypti is multifactorial and age-dependent Mayton, E. H.; Tramonte, A. R.; Christofferson, R. C. 10.1101/552125 — ecology — Posted on 2019-03-06 2682 A survey of fishes of Hombolo Lake, Dodoma, Tanzania, with evidence for local extinction of a native tilapia as a consequence of stocking Turner, G. F.; Ngatunga, B. P.; Genner, M. J. 10.1101/452847 — ecology — Posted on 2019-03-06 2683 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies. Chamaille-Jammes, S. 10.1101/565838 — ecology — Posted on 2019-03-06 2684 FAIM opposes stress-induced loss of viability and blocks the formation of protein aggregates Kaku, H.; Rothstein, T. L. 10.1101/569988 — cell biology — Posted on 2019-03-06 2685 Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma Thomaz, A.; Pinheiro, K. d. V.; Souza, B. K.; Gregianin, L.; Brunetto, A. L.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M. d. C.; Ramaswamy, V.; Nor, C.; Taylor, M. D.; Roesler, R. 10.1101/566000 — cancer biology — Posted on 2019-03-06 2686 Studies of allosteric coupling in KcsA using a constitutively open mutant Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E. 10.1101/567024 — biophysics — Posted on 2019-03-06 2687 Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis Durif, G.; Modolo, L.; Mold, J. E.; Lambert-Lacroix, S.; Picard, F. 10.1101/211938 — bioinformatics — Posted on 2019-03-06 2688 LinkedSV: Detection of mosaic structural variants from linked-read exome and genome sequencing data Fang, L.; Kao, C.; Gonzalez, M. V.; Mafra, F. A.; Pellegrino da Silva, R.; Li, M.; Wenzel, S.; Wimmer, K.; Hakonarson, H.; Wang, K. 10.1101/409789 — bioinformatics — Posted on 2019-03-06 2689 Interpretation of Omics dynamics in a single subject using local estimates of dispersion between two transcriptomes Li, Q.; Rachid Zaim, S.; Aberasturi, D.; Berghout, J.; Li, H.; Vitali, F.; Kenost, C.; Zhang, H. H.; Lussier, Y. A. 10.1101/405332 — bioinformatics — Posted on 2019-03-06 2690 Genetic Basis of Alternative Polyadenylation is an Emerging Molecular Phenotype for Human Traits and Diseases Li, L.; Gao, Y.; Peng, F.; Wagner, E. J.; Li, W. 10.1101/570176 — bioinformatics — Posted on 2019-03-06 2691 Estimating Residue-Specific Accuracies of Protein Structure Models Using Molecular Dynamics Simulations Hu, J.-H.; Xun, S.-N.; Wu, H.-N.; Wu, Y.-D.; Jiang, F. 10.1101/439760 — bioinformatics — Posted on 2019-03-06 2692 A robotic platform for fluidically-linked human body-on-chips experimentation Novak, R.; Ingram, M.; Clauson, S.; Das, D.; Delahanty, A.; Herland, A.; Maoz, B.; Jeanty, S. S. F.; Somayaji, M. R.; Burt, M.; Calamari, E.; Chalkiadaki, A.; Cho, A.; Choe, Y.; Chou, D. B.; Cronce, M.; Dauth, S.; Divic, T.; Fernandez-Alcon, J.; Ferrante, T.; Ferrier, J.; Fitzgerald, E. A.; Fleming, R.; Jalili Firoozinezhad, S.; Grevesse, T.; Goss, J. A.; Hamkins-Indik, T.; Henry, O.; Hinojosa, C.; Huffstater, T.; Jang, K.-J.; Kujala, V.; Leng, L.; Mannix, R.; Milton, Y.; Nawroth, J.; Nestor, B. A.; Ng, C. F.; O'Connor, B.; Park, T.-E.; Sanchez, H.; Sliz, J.; Sontheimer-Phelps, A.; Swenor, B. 10.1101/569541 — bioengineering — Posted on 2019-03-06 2693 AgarFix: simple and accessible stabilization of challenging single-particle cryo-EM specimens through cross-linking in a matrix of agar Adamus, K.; Le, S. N.; Elmlund, H.; Boudes, M.; Elmlund, D. 10.1101/569087 — biochemistry — Posted on 2019-03-06 2694 MRI and cognitive scores complement each other to accurately predict Alzheimer’s dementia 2 to 7 years before clinical onset Zandifar, A.; Fonov, V.; Ducharme, S.; Belleville, S.; Collins, D. L. 10.1101/567867 — neuroscience — Posted on 2019-03-06 2695 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440 Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J. 10.1101/567529 — microbiology — Posted on 2019-03-06 2696 Comparison of single nucleotide variants identified by Illumina and Oxford Nanopore technologies in the context of a potential outbreak of Shiga Toxin Producing Escherichia coli. Dallman, T.; Jenkins, C.; Gharbia, S.; Greig, D. 10.1101/570192 — microbiology — Posted on 2019-03-06 2697 Stiffness and tension gradients of the hair cell’s tip-link complex in the mammalian cochlea Tobin, M.; Chaiyasitdhi, A.; Michel, V.; Michalski, N.; Martin, P. 10.1101/497222 — biophysics — Posted on 2019-03-06 2698 Marine metabolomics: Measurement of metabolites in seawater by gas-chromatography mass spectrometry Sogin, E. M.; Puskas, E.; Dubilier, N.; Liebeke, M. 10.1101/528307 — biochemistry — Posted on 2019-03-06 2699 Anti-tubercular activity of novel 4-anilinoquinolines and 4-anilinoquinazolines Asquith, C. R. M.; Fleck, N.; Grundner, C.; Zuercher, W. J. 10.1101/570002 — pharmacology and toxicology — Posted on 2019-03-06 2700 Retrospective inference as a form of bounded rationality, and its beneficial influence on learning FitzGerald, T. H. B.; Devaux, T.; Penny, W. D.; Bonnici, H.; Adams, R. A. 10.1101/569574 — neuroscience — Posted on 2019-03-06 2701 Excitatory GABAergic signalling is associated with acquired benzodiazepine resistance in status epilepticus Burman, R. J.; Calin, A.; Codadu, N. K.; Wright, R.; Newey, S. E.; van den Berg, M.; Lee, J. H.; Parrish, R. R.; Wilmshurst, J. M.; Akerman, C. J.; Trevelyan, A. J.; Raimondo, J. V. 10.1101/478594 — neuroscience — Posted on 2019-03-06 2702 Decoding mouse behavior to explain single-trial decisions and their relationship with neural activity. Weissenberger, Y.; King, A. J.; Dahmen, J. C. 10.1101/567479 — neuroscience — Posted on 2019-03-06 2703 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R. 10.1101/564617 — neuroscience — Posted on 2019-03-06 2704 The Evolutionary Dynamics and Fitness Landscape of Clonal Haematopoiesis Watson, C. J.; Papula, A.; Poon, Y. P. G.; Wong, W. H.; Young, A. L.; Druley, T. E.; Fisher, D. S.; Blundell, J. R. 10.1101/569566 — genomics — Posted on 2019-03-06 2705 Cassava planting material movement and grower behaviour in Zambia: implications for disease management Szyniszewska, A. M.; Chikoti, P. C.; Tembo, M.; Mulenga, R.; Gilligan, C. A.; van den Bosch, F.; McQuaid, C. F. 10.1101/528851 — epidemiology — Posted on 2019-03-06 2706 Changes in the Biodiversity Intactness Index in tropical and subtropical forest biomes, 2001-2012. De Palma, A.; Hoskins, A.; Gonzalez, R. E.; Newbold, T.; Sanchez-Ortiz, K.; Ferrier, S.; Purvis, A. 10.1101/311688 — ecology — Posted on 2019-03-06 2707 Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis. Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany, A.; Korving, J.; Darmis, F.; van Blitterswijk, C.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C. 10.1101/510362 — developmental biology — Posted on 2019-03-06 2708 Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation Kolitsida, P.; Zhou, J.; Rackiewicz, M.; Nolic, V.; Dengjel, J.; Abeliovich, H. 10.1101/513135 — cell biology — Posted on 2019-03-06 2709 HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness Phenotype in Medulloblastoma Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R. 10.1101/521393 — cancer biology — Posted on 2019-03-06 2710 Ephemeral states in protein folding under force captured with a novel magnetic tweezers design Tapia-Rojo, R.; Eckels, E. C.; Fernandez, J. M. 10.1101/310060 — biophysics — Posted on 2019-03-06 2711 ARG-miner: A web platform for crowdsourcing-based curation of antibiotic resistance genes Argoty, G. A. A.; Guron, G. K.; Garner, E.; Riquelme, M. V.; Heath, L.; Pruden, A.; Vikesland, P.; Zhang, L. 10.1101/274282 — bioinformatics — Posted on 2019-03-06 2712 Report on the spatial spread of defective interfering particles and its role in suppressing infectious particles Ali, Q.; Ke, R. 10.1101/558932 — bioengineering — Posted on 2019-03-06 2713 A Modification of the Bielschowsky Silver Stain for Alzheimer Neuritic Plaques: Suppression of Artifactual Staining by Pretreatment with Oxidizing Agents Intorcia, A. J.; Filon, J. R.; Hoffman, B.; Serrano, G. E.; Sue, L. I.; Beach, T. G. 10.1101/570093 — neuroscience — Posted on 2019-03-06 2714 Identifying genetic determinants of complex phenotypes from whole genome sequence data Long, G. S.; Hussen, M.; Dench, J.; Aris-Brosou, S. 10.1101/181222 — bioinformatics — Posted on 2019-03-06 2715 Bed nucleus of the stria terminalis regulates fear to ambiguous threat signals Goode, T. D.; Ressler, R. L.; Acca, G. M.; Miles, O.; Maren, S. 10.1101/376228 — neuroscience — Posted on 2019-03-06 2716 Activity-dependent long-term potentiation of electrical synapses in the mammalian thalamus Fricker, B.; Heckman, E.; Cunningham, P. C.; Haas, J. 10.1101/570101 — neuroscience — Posted on 2019-03-06 2717 CHaRTr: An R toolbox for modeling Choices and Response Times in decision-making tasks Chandrasekaran, C.; Hawkins, G. 10.1101/570184 — neuroscience — Posted on 2019-03-06 2718 A unified method for rare variant analysis of gene-environment interactions Lim, E.; Chen, H.; Dupuis, J.; Liu, C.-T. 10.1101/570226 — genetics — Posted on 2019-03-06 2719 7q11.23 Syndromes Reveal BAZ1B as a Master Regulator of the Modern Human Face and Validate the Self-Domestication Hypothesis Zanella, M.; Vitriolo, A.; Andirko, A.; Martins, P. T.; Sturm, S.; O'Rourke, T.; Laugsch, M.; Malerba, N.; Skaros, A.; Trattaro, S.; Germain, P.-L.; Merla, G.; Rada-Iglesias, A.; Boeckx, C.; Testa, G. 10.1101/570036 — evolutionary biology — Posted on 2019-03-06 2720 An integrated workflow for cross-linking/mass spectrometry Mendes, M. L.; Fischer, L.; Chen, Z. A.; Barbon, M.; O'Reilly, F. J.; Giese, S.; Bohlke-Schneider, M.; Belsom, A.; Dau, T.; Combe, C. W.; Graham, M.; Eisele, M. R.; Baumeister, W.; Speck, C.; Rappsilber, J. 10.1101/355396 — biochemistry — Posted on 2019-03-06 2721 DUX is a non-essential synchronizer of zygotic genome activation De Iaco, A.; Verp, S.; Offner, S.; Trono, D. 10.1101/569434 — developmental biology — Posted on 2019-03-06 2722 A hierarchical approach to model decision making: a study in chemotactic behavior of Escherichia coli Vafadar, S.; Kavousi, K.; Safdari, H.; Kalirad, A.; Sadeghi, M. 10.1101/569277 — systems biology — Posted on 2019-03-06 2723 Th2 cytokine profile in appendicular lavage fluid is compatible with allergy as an etiology for acute appendicitis Carvalho, N.; Barros, A.; Coelho, H. O.; Moita, C. F.; Neves-Costa, A.; Borges, F. C.; Moita, L. F.; Costa, P. 10.1101/569947 — pathology — Posted on 2019-03-06 2724 Transduction of gluconeogenic enzymes prolongs cone photoreceptor survival and function in models of retinitis pigmentosa Chinchore, Y.; Begaj, T.; Guillermeir, C.; Steinhauser, M. L.; Punzo, C.; Cepko, C. L. 10.1101/569665 — neuroscience — Posted on 2019-03-06 2725 Decoding P300 Variability using Convolutional Neural Networks Solon, A. J.; Lawhern, V. J.; Touryan, J.; McDaniel, J. R.; Ries, A. J.; Gordon, S. M. 10.1101/569616 — neuroscience — Posted on 2019-03-06 2726 Neonatal morphometric similarity mapping for predicting brain age and characterizing neuroanatomic variation associated with preterm birth Galdi, P.; Blesa Cabez, M.; Stoye, D. Q.; Sullivan, G.; Lamb, G. J.; Quigley, A. J.; Thrippleton, M. J.; Bastin, M. E.; Boardman, J. P. 10.1101/569319 — neuroscience — Posted on 2019-03-06 2727 Machine learning Classification of Dyslexic Children based on EEG Local Network Features Rezvani, Z.; Zare, M.; Zaric, G.; Bonte, M.; Tijms, J.; van der Molen, M.; Gonzalez, G. F. 10.1101/569996 — neuroscience — Posted on 2019-03-06 2728 Differential requirements of cyclase associated protein (CAP) for actin turnover during the lytic cycle of Toxoplasma gondii Hunt, A.; Wagener, J.; Kent, R.; Carmeille, R.; Russell, M.; Peddie, C.; Collinson, L.; Heaslip, A.; Ward, G. E.; Treeck, M. 10.1101/569368 — microbiology — Posted on 2019-03-06 2729 Genome-wide association analysis for resistance to infectious pancreatic necrosis virus identifies candidate genes involved in viral replication and immune response in rainbow trout (Oncorhynchus mykiss) Rodrigues, F.; Flores-Mara, R.; Yoshida, G.; Barria, A.; Jedlicki, A.; Lhorente, J. P.; Reyes, F.; Yanez, J. 10.1101/569632 — genomics — Posted on 2019-03-06 2730 The flickering connectivity system of the north Andean paramos Flantua, S. G. A.; O'Dea, A.; Onstein, R. E.; Hooghiemstra, H. 10.1101/569681 — ecology — Posted on 2019-03-06 2731 Distinct defense strategies allow different grassland species to cope with root herbivore attack Herve, M.; Erb, M. 10.1101/569533 — ecology — Posted on 2019-03-06 2732 Asymmetric Division Promotes Therapeutic Resistance In Glioblastoma Stem Cells Hitomi, M.; Chumakova, A. P.; Silver, D. J.; Knudsen, A. M.; Pontius, W. D.; Murphy, S.; Anand, N.; Kristensen, B. W.; Lathia, J. D. 10.1101/569962 — cancer biology — Posted on 2019-03-06 2733 Network analysis allows to unravel breast cancer molecular features and to identify novel targets Savino, A.; Avalle, L.; Monteleone, E.; Miglio, I.; Griffa, A.; Accetta, G.; Provero, P.; Poli, V. 10.1101/570051 — cancer biology — Posted on 2019-03-06 2734 Unearthing Regulatory Axes of Breast Cancer circRNAs Networks to Find Novel Targets and Fathom Pivotal Mechanisms Afzali, F.; Salimi, M. 10.1101/569756 — bioinformatics — Posted on 2019-03-06 2735 Interaction Effects of Apolipoprotein E ε 4 and Cognitive Status on the Functional Connectivity within Default Mode Network in Individuals at Risk of Cognitive Impairments Lu, H.; Ma, S. L.; Wing, W. C. C.; Wong, S. W. H.; Lam, L. C. W. 10.1101/565812 — neuroscience — Posted on 2019-03-06 2736 Motor fatigability as evoked by repetitive movements results from a gradual breakdown of surround inhibition Baechinger, M.; Lehner, R.; Thomas, F.; Hanimann, S.; Balsters, J. H.; Wenderoth, N. 10.1101/569608 — neuroscience — Posted on 2019-03-06 2737 Development of high throughput methods for the analysis of anthelmintic resistance allele frequencies in field populations of gastrointestinal nematodes. Sargison, N. D.; MacLeay, M.; Morrison, A. A.; Bartley, D. J.; Evans, M.; Chaudhry, U. 10.1101/569863 — molecular biology — Posted on 2019-03-06 2738 Afucosylated maternal anti-dengue IgGs are a biomarker for susceptibility to dengue disease in their infants Thulin, N. K.; Brewer, R. C.; Sherwood, R.; Bournazos, S.; Edwards, K. G.; Ramadoss, N. S.; Taubenberger, J. K.; Memoli, M.; Jagannathan, P.; Zhang, S.; Libraty, D. H.; Wang, T. T. 10.1101/565259 — immunology — Posted on 2019-03-06 2739 β-Caryophyllene Enhances the Transcriptional Upregulation of Cholesterol Biosynthesis in Breast Cancer Cells Mboge, M. Y.; Ramirez-Mata, A.; Bullock, A.; O'Donnell, R.; Mathias, J.; Davila, J.; Frost, C. J.; Frost, S. C. 10.1101/569558 — cancer biology — Posted on 2019-03-06 2740 Methods for Analyzing Imaging Mass Cytometry Data with Tellurium Probes Bassan, J.; Nitz, M. 10.1101/567685 — bioinformatics — Posted on 2019-03-06 2741 Wnt7a-releasing synthetic hydrogel enhances local skeletal muscle regeneration and muscle stem cell engraftment Han, W. M.; Mohiuddin, M.; Anderson, S. E.; Garcia, A. J.; Jang, Y. C. 10.1101/569921 — bioengineering — Posted on 2019-03-06 2742 Xenogeneic regulation of the ClpCP protease of Bacillus subtilis by a phage-encoded adaptor-like protein Mulvenna, N.; Hantke, I.; Burchell, L.; Nicod, S.; Turgay, K.; Wigneshweraraj, R. 10.1101/569657 — microbiology — Posted on 2019-03-06 2743 Mechanistic characterization of RASGRP1 variants identifies an hnRNP K-regulated transcriptional enhancer contributing to SLE susceptibility Molineros, J. E.; Singh, B.; Terao, C.; Okada, Y.; Kaplan, J.; McDaniel, B.; Akizuki, S.; Sun, C.; Webb, C.; Looger, L. L.; Nath, S. K. 10.1101/568790 — genetics — Posted on 2019-03-06 2744 RhizoVision Crown: An Integrated Hardware and Software Platform for Root Crown Phenotyping Seethepalli, A.; Guo, H.; Liu, X.; Griffiths, M.; Almtarfi, H.; Li, Z.; Liu, S.; Zare, A.; Fritschi, F.; Blancaflor, E.; Ma, X.; York, L. M. 10.1101/569707 — plant biology — Posted on 2019-03-06 2745 Emergence of Functional Cortical Patterns of neurons characterize the self-organizing way to cognition in brain. Gund, J.; Singh, R. K. B. 10.1101/569244 — neuroscience — Posted on 2019-03-06 2746 Genetic mapping of fitness determinants across the malaria parasite Plasmodium falciparum life cycle Li, X.; Kumar, S.; McDew-White, M.; Haile, M.; Cheeseman, I. H.; Emrich, S.; Button-Simons, K.; Nosten, F.; Kappe, S.; Ferdig, M.; Anderson, T.; Vaughan, A. 10.1101/570085 — evolutionary biology — Posted on 2019-03-06 2747 MetaMLP: A fast word embedding based classifier to profile target gene databases in metagenomic samples Arango-Argoty, G. A.; Heath, L. S.; Pruden, A.; Vikesland, P.; Zhang, L. 10.1101/569970 — bioinformatics — Posted on 2019-03-06 2748 Genomic landscape of 261 childhood cancer patient-derived xenograft models Rokita, J. L.; Rathi, K. S.; Cardenas, M. F.; Upton, K. A.; Jayaseelan, J.; Cross, K. L.; Pfeil, J.; Ritenour, L. E.; Modi, A.; Farrel, A.; Way, G. P.; Kendsersky, N. M.; Patel, K.; Lopez, G.; Vaksman, Z.; Mayoh, C.; Nance, J.; McCoy, K.; Haber, M.; Evans, K.; McCalmont, H.; Bendak, K.; Bohm, J. W.; Marshall, G. M.; Tyrrell, V.; Kalletla, K.; Braun, F. K.; Qi, L.; Du, Y.; Zhang, H.; Lindsay, H. B.; Zhao, S.; Shu, J.; Baxter, P.; Morton, C.; Kurmashev, D.; Zheng, S.; Chen, Y.; Bowen, J.; Bryan, A. C.; Leraas, K. M.; Coppens, S. E.; Doddapaneni, H.; Momin, Z.; Zhang, W.; Sacks, G. I.; Hart, L. S 10.1101/566455 — genomics — Posted on 2019-03-06 2749 Keeping salamanders off the streets: An assessment of one of the first amphibian road tunnels in the United States 30 years after installation Hedrick, B.; Vander Linden, A.; Watt, E.; O'Roark, P.; Cordero, S.; Sutherland, C. 10.1101/569426 — ecology — Posted on 2019-03-06 2750 High ribulose-1,5-bisphosphate carboxylase/oxygenase content in northern diatom species Gerecht, A. C.; Eriksen, G. K.; Uradnikova, M.; Eilertsen, H. C. 10.1101/569285 — ecology — Posted on 2019-03-06 2751 CUT&Tag for efficient epigenomic profiling of small samples and single cells Kaya-Okur, H. S.; Wu, S. J.; Codomo, C. A.; Pledger, E. S.; Bryson, T. D.; Henikoff, J. G.; Ahmad, K.; Henikoff, S. 10.1101/568915 — genomics — Posted on 2019-03-06 2752 Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program Taliun, D.; Harris, D. N.; Kessler, M. D.; Carlson, J.; Szpiech, Z. A.; Torres, R.; Gagliano Taliun, S. A.; Corvelo, A.; Gogarten, S. M.; Min Kang, H.; Pitsillides, A. N.; LeFaive, J.; Lee, S.-b.; Tian, X.; Browning, B. L.; Das, S.; Emde, A.-K.; Clarke, W. E.; Loesch, D. P.; Shetty, A. C.; Blackwell, T. W.; Wong, Q.; Aguet, F.; Albert, C.; Alonso, A.; Ardlie, K. G.; Aslibekyan, S.; Auer, P. L.; Barnard, J.; Barr, R. G.; Becker, L. C.; Beer, R. L.; Benjamin, E. J.; Bielak, L. F.; Blangero, J.; Boehnke, M.; Bowden, D. W.; Brody, J. A.; Burchard, E. G.; Cade, B. E.; Casella, J. F.; Chalazan, B. L 10.1101/563866 — genomics — Posted on 2019-03-06 2753 Demonstration of simultaneous biological sulphate reduction and partial sulphide oxidation in a hybrid linear flow channel reactor Marais, T. S.; Huddy, R.; Harrison, S. T. L.; van Hille, R. 10.1101/569269 — bioengineering — Posted on 2019-03-06 2754 Chemical screening pipeline for identification of specific plant autophagy modulators Dauphinee, A. N.; Cardoso, C.; Dalman, K.; Ohlsson, J.; Berglund Fick, S.; Robert, S.; Hicks, G. R.; Bozhkov, P. V.; Minina, E. A. 10.1101/569327 — plant biology — Posted on 2019-03-06 2755 A comparison of DNA stains and staining methods for Agarose Gel Electrophoresis Hall, A. C. 10.1101/568253 — molecular biology — Posted on 2019-03-06 2756 GSTM1 copy number is not associated with risk of kidney failure in a large cohort Zhang, Y.; Zafar, W.; Hartzel, D. N.; Williams, M. S.; Tin, A.; Chang, A. R.; Regeneron Genetics Center, ; Lee, M. T. M. 10.1101/567651 — genetics — Posted on 2019-03-06 2757 Back-propagation learning in deep Spike-By-Spike networks Rotermund, D.; Pawelzik, K. R. 10.1101/569236 — bioinformatics — Posted on 2019-03-06 2758 Robust Hierarchical Density Estimation and Regression for Re-stained Histological Whole Slide Image Co-registration Jiang, J.; Larson, N.; Prodduturi, N.; Flotte, T.; Hart, S. 10.1101/565564 — bioinformatics — Posted on 2019-03-06 2759 Implicit semantic prediction error can account for N400 effects on articles that do not differ in meaning: A neural network model Rabovsky, M. 10.1101/569020 — neuroscience — Posted on 2019-03-06 2760 Towards next generation diagnostics for tuberculosis: identification of novel molecular targets by large-scale comparative genomics Goig, G. A.; Torres-Puente, M.; Mariner Llicer, C.; Villamayor, L. M.; Chiner-Oms, A.; Gil-Brusola, A.; Borras, R.; Comas, I. 10.1101/569384 — microbiology — Posted on 2019-03-06 2761 Notch signaling and taxis mechanims regulate early stage angiogenesis: A mathematical and computational model Vega, R.; Carretero, M.; Travasso, R. D. M.; Bonilla, L. L. 10.1101/569897 — systems biology — Posted on 2019-03-06 2762 Complex interaction networks of cytokines after transarterial chemotherapy in patients with hepatocellular carcinoma JEKARL, D. W.; Lee, S.; Kwon, J. H.; Nam, S. W.; Jang, J. W.; Kim, M.; Kim, Y. 10.1101/569939 — immunology — Posted on 2019-03-06 2763 Hydrology-informed metapopulation modeling of liver fluke transmission in the Lawa Lake complex of northeast Thailand Leon, T. M.; Plermkamon, V.; Kuntiyawichai, K.; Sripa, B.; Spear, R. C. 10.1101/569913 — epidemiology — Posted on 2019-03-06 2764 Determination of glucosinolate contents in Brassica germplasm collections and inter- & intra-leaves distribution pattern using UPLC-MS/MS Multiple Reaction Monitoring scan mode Assefa, A. D.; Choi, S.; Lee, J.-E.; Sung, J.-S.; Hur, O.-S.; Ro, N.-Y.; Lee, H.-S.; Noh, J.; Hwang, A.; Ko, H.-C.; Chung, Y.-J.; Rhee, J. H. 10.1101/569889 — biochemistry — Posted on 2019-03-06 2765 Assessing introgressive hybridization in roan antelope (Hippotragus equinus): Lessons from South Africa van Wyk, A. M. L.; Dalton, D. L.; Kotze, A. L.; Grobler, J. P.; Mokgokong, P. S. L.; Kropff, A. S. L.; Jansen van Vuuren, B. 10.1101/569830 — zoology — Posted on 2019-03-06 2766 Saxitoxin and tetrodotoxin bioavailability increases in future oceans Roggatz, C. C.; Fletcher, N.; Benoit, D. M.; Algar, A. C.; Doroff, A.; Wright, B.; Wollenberg Valero, K. C.; Hardege, J. D. 10.1101/562694 — pharmacology and toxicology — Posted on 2019-03-06 2767 High prevalence of antibiotic resistance in Helicobacter pylori isolates from Iran: importance of functional and mutational analysis of resistance genes and virulence genotyping Farzi, N.; Yadegar, A.; Asadzadeh Aghdaei, H.; Sadeghi, A.; Zali, M. R. 10.1101/569814 — microbiology — Posted on 2019-03-06 2768 Ciliary Genes arl13b, ahi1 and cc2d2a Differentially Modify Expression of Visual Acuity Phenotypes but do not Enhance Retinal Degeneration due to Mutation of cep290 in Zebrafish Perkins, B.; Lessieur, E.; Song, P.; Nivar, G.; Piccillo, E.; Fogerty, J.; Rozic, R. 10.1101/569822 — cell biology — Posted on 2019-03-06 2769 An Analytic Platform for the Rapid and Reproducible Annotation of Ventilator Waveform Data Rehm, G. B.; Kuhn, B. T.; Lieng, M. K.; Cortes-Puch, I.; Nguyen, J.; Guo, E.; Delplanque, J.-P.; Anderson, N. R.; Adams, J. Y. 10.1101/568386 — physiology — Posted on 2019-03-06 2770 Time-series genome-centric analysis unveils bacterial response to operational disturbance in activated sludge Perez, M. V.; Guerrero, L. D.; Orellana, E.; Figuerola, E. L.; Erijman, L. 10.1101/565770 — microbiology — Posted on 2019-03-06 2771 Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes Associated with Age at Menarche and Age at Natural Menopause An, Y.; Wang, G.; LV, J.; Qiu, X. 10.1101/569731 — genetics — Posted on 2019-03-06 2772 Impact of pterygium on the ocular surface and meibomian glands Wanzeler, A.; Barbosa, I. A. F.; Duarte, B.; Barbosa, E. B.; Borges, D. A.; Alves, M. 10.1101/569772 — epidemiology — Posted on 2019-03-06 2773 Non-linear dendritic integration in frontal circuits shapes sensory discrimination in rodents Aime, M.; Augusto, E.; Kouskoff, V.; Martin, C.; Humeau, Y.; Chenouard, N.; Gambino, F. 10.1101/569137 — neuroscience — Posted on 2019-03-06 2774 Quantitative multiplexed ChIP reveals global alterations that shape promoter bivalency in ground state embryonic stem cells Kumar, B.; Elsässer, S. J. 10.1101/557082 — molecular biology — Posted on 2019-03-06 2775 Elucidation of the viral disassembly switch of tobacco mosaic virus Weis, F.; Beckers, M.; von der Hocht, I.; Sachse, C. 10.1101/569178 — molecular biology — Posted on 2019-03-06 2776 How to make more from exposure data? An integrated machine learning pipeline to predict pathogen exposure Fountain-Jones, N.; Machado, G.; Carver, S.; Packer, C.; Mendoza, M.; Craft, M. E. 10.1101/569012 — ecology — Posted on 2019-03-06 2777 Base pairing interactions between substrate RNA and H/ACA guide RNA modulate the kinetics of pseudouridylation, but not the affinity of substrate binding by H/ACA small nucleolar Ribonucleoproteins Kelly, E. K.; Kothe, U. 10.1101/569061 — biochemistry — Posted on 2019-03-06 2778 A common tag nucleotide variant in MMP7 promoter increases risk for hypertension via enhanced interactions with CREB transcription factor Subramanian, L.; Maghajothi, S.; Singh, M.; Kesh, K.; Ananthamohan, K.; Sharma, S.; Khullar, M.; Victor, S. M.; Swarnakar, S.; Asthana, S.; Mullasari, A. S.; Mahapatra, N. R. 10.1101/568774 — genetics — Posted on 2019-03-06 2779 Large-scale kinetic metabolic models of Pseudomonas putida for a consistent design of metabolic engineering strategies Tokic, M.; Miskovic, L.; Hatzimanikatis, V. 10.1101/569152 — systems biology — Posted on 2019-03-06 2780 Absence of entourage: Terpenoids commonly found in Cannabis sativa do not modulate the functional activity of Δ9-THC at human CB1 and CB2 receptors Santiago, M. J.; Sachdev, S.; Arnold, J. C.; McGregor, I. S.; Connor, M. 10.1101/569079 — pharmacology and toxicology — Posted on 2019-03-06 2781 Urinary biomarker and histopathological evaluation of vancomycin and piperacillin-tazobactam nephrotoxicity in comparison with vancomycin in a rat model and a confirmatory cellular model Pais, G. M.; Liu, J.; Avedissian, S. N.; Xanthos, T.; Chalkias, A.; d'Aloja, E.; Locci, E.; Gilchrist, A.; Prozialeck, W. C.; Rhodes, N.; Lodise, T. P.; Fitzgerald, J. C.; Downes, K.; Zuppa, A.; Scheetz, M. H. 10.1101/568907 — pharmacology and toxicology — Posted on 2019-03-06 2782 Visual and auditory information shed light on savings mechanisms White, O.; Barbiero, M.; Marechal, Q.; Orban de Xivry, J.-J. 10.1101/569186 — neuroscience — Posted on 2019-03-06 2783 Neural Correlates of Cognition in Primary Visual versus Neighboring Posterior Cortices during Visual Evidence-Accumulation-based Navigation Koay, S. A.; Thiberge, S. Y.; Brody, C.; Tank, D. W. 10.1101/568766 — neuroscience — Posted on 2019-03-06 2784 Genetic Polymorphisms and Molecular Mechanisms Mediating Oncolytic Potency of Reovirus Strains Mohamed, A.; Clements, D. R.; Konda, P.; Gujar, S. A.; Lee, P.; Smiley, J. R.; Shmulevitz, M. 10.1101/569301 — microbiology — Posted on 2019-03-06 2785 Identification of Genes Regulating Cell Death in Staphylococcus aureus Yee, R.; Feng, J.; Wang, J.; Chen, J.; ZHANG, Y. 10.1101/569053 — microbiology — Posted on 2019-03-06 2786 Functional metagenomics-guided discovery of potent Cas9 inhibitors in the human microbiome Forsberg, K. J.; Bhatt, I. V.; Schmidtke, D. T.; Stoddard, B. L.; Kaiser, B. K.; Malik, H. S. 10.1101/569095 — microbiology — Posted on 2019-03-06 2787 Gut feelings begin in childhood: how the gut metagenome links to early environment, caregiving, and behavior Flannery, J.; Stagaman, K.; Burns, A. R.; Hickey, R. J.; Roos, L. E.; Giuliano, R. J.; Fisher, P.; Sharpton, T. 10.1101/568717 — microbiology — Posted on 2019-03-06 2788 A topological data analysis based classification method for multiple measurement Riihimaki, H.; Chacholski, W.; Theorell, J.; Hillert, J.; Ramanujam, R. 10.1101/569210 — bioinformatics — Posted on 2019-03-06 2789 Perturbation biology links temporal protein changes to drug responses in a melanoma cell line Nyman, E.; Stein, R. R.; Jing, X.; Wang, W.; Marks, B.; Zervantonakis, I. K.; Korkut, A.; Gauthier, N. P.; Sander, C. 10.1101/568758 — systems biology — Posted on 2019-03-06 2790 A streamlined protocol and analysis pipeline for CUT&RUN chromatin profiling Meers, M. P.; Bryson, T. D.; Henikoff, S. 10.1101/569129 — molecular biology — Posted on 2019-03-06 2791 Chromosome-wide co-fluctuation of stochastic gene expression in mammalian cells Sun, M.; Zhang, J. G. 10.1101/569004 — genomics — Posted on 2019-03-06 2792 Geography Shapes the Population Genomics of Salmonella enterica Dublin Fenske, G.; Thachil, A. J.; McDonough, P. L.; Glaser, A. L.; Scaria, J. 10.1101/569145 — genomics — Posted on 2019-03-06 2793 A Role for Gαz in regulating seizure susceptibility Hultman, R.; Boms, O.; Mague, S. D.; Hughes, D.; Nadler, V.; Dzirasa, K.; Casey, P. J. 10.1101/567628 — neuroscience — Posted on 2019-03-06 2794 AgarFix: simple and accessible stabilization of challenging single-particle cryo-EM specimens through cross-linking in a matrix of agar Adamus, K.; Boudes, M.; Le, S. N.; Elmlund, H.; Elmlund, D. 10.1101/569087 — biochemistry — Posted on 2019-03-06 2795 What the odor is not: Estimation by elimination Singh, V.; Tchernookov, M.; Balasubramanian, V. 10.1101/568626 — neuroscience — Posted on 2019-03-06 2796 Mutation profiling of both cfDNAs and CTCs in gynecological cancer patients Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Bhak, J.; Kim, B. C.; Cho, D.-H. 10.1101/566786 — genetics — Posted on 2019-03-06 2797 On the importance of accounting for intraspecific genomic relatedness in multi-species studies Joly, S.; Flynn, D. F. B.; Wolkovich, E. 10.1101/321927 — ecology — Posted on 2019-03-06 2798 Homotypic and heterotypic trans-assembly of human Rab-family small GTPases in reconstituted membrane tethering Segawa, K.; Tamura, N.; Mima, J. 10.1101/544379 — cell biology — Posted on 2019-03-06 2799 Moments reconstruction and local dynamic range compression of high order Superresolution Optical Fluctuation Imaging Yi, X.; Son, S.; Ando, R.; Miyawaki, A.; Weiss, S. 10.1101/500819 — bioengineering — Posted on 2019-03-06 2800 Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites. Basbous, J.; Aze, A.; Chaloin, L.; Lebdy, R.; Hodroj, D.; Ribeyre, C.; Larroque, M.; Shepard, C.; Kim, B.; Pruvost, A.; Moreaux, J.; Maiorano, D.; Mechali, M.; Constantinou, A. 10.1101/420893 — cancer biology — Posted on 2019-03-05 2801 Contribution of Apical and Basal Dendrites of L2/3 Pyramidal Neurons to Orientation Encoding in Mouse V1 Park, J.; Papoutsi, A.; Ash, R. T.; Marin, M. A.; Poirazi, P.; Smirnakis, S. M. 10.1101/566588 — neuroscience — Posted on 2019-03-05 2802 Shared neural underpinnings of multisensory integration and trial-by-trial perceptual recalibration Park, H.; Kayser, C. 10.1101/566927 — neuroscience — Posted on 2019-03-05 2803 Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3 Erlichster, M.; Bedo, J.; Skafidas, E.; Kwan, P.; Kowalczyk, A.; Goudey, B. 10.1101/561308 — genetics — Posted on 2019-03-05 2804 A Signaling Network based Computational Model to Uncover Loop as the Novel Molecular Mechanisms for Medulloblastoma Xu, J.; Li, F. 10.1101/561076 — bioinformatics — Posted on 2019-03-05 2805 Somatostatin-Expressing Interneurons Co-Release GABA and Glutamate onto Different Postsynaptic Targets in the Striatum. Cattaneo, S.; Zaghi, M.; Ripamonti, M.; Bedogni, F.; Sessa, A.; Taverna, S. 10.1101/566984 — neuroscience — Posted on 2019-03-05 2806 Learning what is irrelevant or relevant: Expectations facilitate distractor inhibition and target facilitation through distinct neural mechanisms van Moorselaar, D.; Slagter, H. A. 10.1101/565069 — neuroscience — Posted on 2019-03-05 2807 Functional arrays of human pluripotent stem cell-derived cardiac microtissues Thavandiran, N.; Hale, C.; Blit, P.; Sandberg, M. L.; McElvain, M. E.; Gagliardi, M.; Sun, B.; Witty, A.; Graham, G.; McIntosh, M.; Bakooshli, M. A.; Le, H.; Ostblom, J.; McEwen, S.; Chau, E.; Prowse, A.; Fernandes, I.; Gilbert, P. M.; Keller, G.; Tagari, P.; Xu, H.; Radisic, M.; Zandstra, P. 10.1101/566059 — bioengineering — Posted on 2019-03-05 2808 Genetic, epigenetic and pharmacological influences modulating tissue specific regulation of the cannabinoid receptor -1 (CB1) gene; implications for cannabinoid pharmacogenetics. Hay, E. A.; Cowie, P. D.; McEwan, A. R.; Wilson, D.; Ross, R.; Barrett, P.; Pertwee, R. G.; MacKenzie, A. 10.1101/544585 — genetics — Posted on 2019-03-05 2809 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies. Chamaille-Jammes, S. 10.1101/565838 — ecology — Posted on 2019-03-05 2810 Lytic bacteriophage have diverse indirect effects in a synthetic cross-feeding community Fazzino, L.; Anisman, J.; Chacon, J. M.; Heineman, R. H.; Harcombe, W. R. 10.1101/560037 — systems biology — Posted on 2019-03-05 2811 Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM-ULM interaction Talkish, J.; Igel, H.; Hunter, O.; Horner, S. W.; Jeffery, N. N.; Leach, J. R.; Jenkins, J. L.; Kielkopf, C. L.; Ares, M. 10.1101/534347 — molecular biology — Posted on 2019-03-05 2812 HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome Asquith, M.; Sternes, P. R.; Costello, M.-E.; Karstens, L.; Diamond, S.; Martin, T. M.; Spector, T. D.; le Cao, K.-A.; Rosenbaum, J. T.; Brown, M. A. 10.1101/517813 — microbiology — Posted on 2019-03-05 2813 High-throughput single-particle tracking reveals nested membrane nanodomain organization that dictates Ras diffusion and trafficking Lee, Y.; Phelps, C.; Huang, T.; Mostofian, B.; Wu, L.; Zhang, Y.; Chang, Y. H.; Stork, P. J. S.; Gray, J. W.; Zuckerman, D. M.; Nan, X. 10.1101/552075 — biophysics — Posted on 2019-03-05 2814 HABIT - a webserver for interactive T cell neoepitope discovery Martins, J.; Magalhaes, C.; Vieira, V.; Rocha, M.; Osorio, N. S. S. 10.1101/535716 — bioinformatics — Posted on 2019-03-05 2815 Engineered Enzymes that Retain and Regenerate their Cofactors Enable Continuous-Flow Biocatalysis Hartley, C. J.; Williams, C. C.; Scoble, J. A.; Churches, Q. I.; French, N. G.; Nebl, T.; Coia, G.; Warden, A. C.; Simpson, G.; Frazer, A.; North, A.; Nixon Jensen, C.; Turner, N. J.; Scott, C. 10.1101/568972 — synthetic biology — Posted on 2019-03-05 2816 Adapterama III: Quadruple-indexed, double/triple-enzyme RADseq libraries (2RAD/3RAD) Bayona-Vasquez, N. J.; Glenn, T. C.; Kieran, T. J.; Pierson, T. W.; Hoffberg, S. L.; Scott, P. A.; Bentley, K. E.; Finger, J. W.; Louha, S.; Troendle, N.; Diaz-Jaimes, P.; Mauricio, R.; Faircloth, B. C. 10.1101/205799 — genomics — Posted on 2019-03-05 2817 Interaction of Hippocampal Ripples and Cortical Slow Waves Leads to Coordinated Large-Scale Sleep Rhythm Sanda, P.; Malerba, P.; Jiang, X.; Krishnan, G.; Cash, S.; Halgren, E.; Bazhenov, M. 10.1101/568881 — neuroscience — Posted on 2019-03-05 2818 α-integrins dictate distinct modes of type IV collagen recruitment to basement membranes Jayadev, R.; Chi, Q.; Keeley, D.; Hastie, E.; Sherwood, D. 10.1101/568964 — cell biology — Posted on 2019-03-05 2819 CA1 pyramidal cells organize an episode by segmented and ordered events Sun, C.; Yang, W.; Martin, J.; Tonegawa, S. 10.1101/565689 — neuroscience — Posted on 2019-03-05 2820 Testing the role of cognitive inhibition in physical endurance using high-definition transcranial direct current stimulation over the prefrontal cortex. Denis, G.; Zory, R.; Radel, R. 10.1101/566901 — neuroscience — Posted on 2019-03-05 2821 Afferent-efferent connectivity between auditory brainstem and cortex accounts for poorer speech-in-noise comprehension in older adults Bidelman, G. M.; Price, C. N.; Shen, D.; Arnott, S.; Alain, C. 10.1101/568840 — neuroscience — Posted on 2019-03-05 2822 Auditory sensory memory span for duration is severely curtailed in females with Rett Syndrome. Brima, T. J.; Molholm, S.; Molloy, C. J.; Sysoeva, O. V.; Nicholas, E.; Djukic, A.; Freedman, E.; Foxe, J. J. 10.1101/568832 — neuroscience — Posted on 2019-03-05 2823 Temperature accounts for the biodiversity of a hyperdiverse group of insects in urban Los Angeles McGlynn, T. P.; Meineke, E. K.; Bahlai, C. A.; Li, E.; Hartop, E. A.; Adams, B. J.; Brown, B. V. 10.1101/568212 — ecology — Posted on 2019-03-05 2824 Analysis of single nucleotide variants in CRISPR-Cas9 edited zebrafish embryos shows no evidence of off-target inflation Katsanis, N.; Mooney, M.; Davis, E. E. 10.1101/568642 — developmental biology — Posted on 2019-03-05 2825 In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex which supports oogenesis Guioli, S.; Zhao, D.; Nandi, S.; Clinton, M.; Lovell-Badge, R. 10.1101/568691 — developmental biology — Posted on 2019-03-05 2826 A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells Mboge, M. Y.; Chen, Z.; Khokhar, D.; Wolff, A.; Ai, L.; Heldermon, C. D.; Boxdag, M.; Carta, F.; Supuran, C. T.; Brown, K. D.; McKenna, R.; Frost, C. J.; Frost, S. C. 10.1101/505644 — cancer biology — Posted on 2019-03-05 2827 Mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells Wollman, A.; Hedlund, E.; Shashkova, S.; Leake, M. 10.1101/568675 — biophysics — Posted on 2019-03-05 2828 Effects of lipid composition on membrane distribution and permeability of natural quinones Teixeira, M. H.; Arantes, G. M. 10.1101/568816 — biophysics — Posted on 2019-03-05 2829 Pacing behaviour in laboratory macaques is an unreliable indicator of acute stress. Poirier, C.; Oliver, C. J.; Flecknell, P.; Bateson, M. 10.1101/568378 — animal behavior and cognition — Posted on 2019-03-05 2830 Single-organelle quantification reveals the stoichiometric and structural variability of carboxysomes dependent on the environment Sun, Y.; Wollman, A.; Huang, F.; Leake, M. C.; Liu, L. 10.1101/568238 — biophysics — Posted on 2019-03-05 2831 Dynamic neuronal activation of a distributed cortico-basal ganglia-thalamus loop in learning a delayed sensorimotor task Gu, X.; Li, C. T. 10.1101/568055 — neuroscience — Posted on 2019-03-05 2832 The caudate nucleus contributes causally to decisions that combine noisy visual evidence and reward context Doi, T.; Fan, Y.; Gold, J. I.; Ding, L. 10.1101/568733 — neuroscience — Posted on 2019-03-05 2833 Postural representations of the hand in primate sensorimotor cortex Goodman, J. M.; Tabot, G. A.; Lee, A. S.; Suresh, A. K.; Rajan, A. T.; Hatsopoulos, N. G.; Bensmaia, S. J. 10.1101/566539 — neuroscience — Posted on 2019-03-05 2834 Effect of task and attention on neural tracking of speech Vanthornhout, J.; Decruy, L.; Francart, T. 10.1101/568204 — neuroscience — Posted on 2019-03-05 2835 The Trichoplax microbiome: the simplest animal lives in an intimate symbiosis with two intracellular bacteria Gruber-Vodicka, H. R.; Leisch, N.; Kleiner, M.; Hinzke, T.; Liebeke, M.; McFall-Ngai, M.; Hadfield, M. G.; Dubilier, N. 10.1101/568287 — microbiology — Posted on 2019-03-05 2836 Single cell transcriptomics identifies immunologic priming related to extra corporeal life support survival. Kort, E. J.; Weiland, M.; Grins, E.; Eugster, E.; Milliron, H.-y.; Kelty, C.; Shrestha, N. M.; Timek, T.; Leacche, M.; Fitch, S.; Boeve, T.; Marco, G.; Dickinson, M.; Wilton, P.; Jovinge, S. 10.1101/568659 — genomics — Posted on 2019-03-05 2837 Is it reasonable to use of a kinship matrix for best linear unbiased prediction? Kim, B. 10.1101/568782 — genetics — Posted on 2019-03-05 2838 A cis-regulatory change underlying the motor neuron-specific loss of terminal selector gene expression in immotile tunicate larvae Lowe, E. K.; Racioppi, C.; Peyrieras, N.; Ristoratore, F.; Christiaen, L.; Swalla, B. J.; Stolfi, A. 10.1101/567719 — evolutionary biology — Posted on 2019-03-05 2839 Proteomic profiling of the oncogenic septin 9 reveals isoform-specific interactions in breast cancer cells Devlin, L.; Perkins, G.; Bowen, J. R.; Montagna, C.; Spiliotis, E. T. 10.1101/566513 — cell biology — Posted on 2019-03-05 2840 Molecular model of the nuclear pore complex reveals a thermoreversible FG-network with distinct territories occupied by different FG motifs Huang, K.; Tagliazucchi, M.; Park, S. H.; Rabin, Y.; Szleifer, I. 10.1101/568865 — cell biology — Posted on 2019-03-05 2841 Stalk Lodging: A Portable Device for Phenotyping Stalk Bending Strength of Maize and Sorghum Cook, D. D.; de la Chapelle, W.; Lin, T.-C.; Lee, S. Y.; Sun, W.; Robertson, D. J. 10.1101/567578 — bioengineering — Posted on 2019-03-05 2842 Early changes in the urine proteome in a rat liver tumor model Yameng, Z.; Yufei, G.; Youhe, G. 10.1101/568246 — biochemistry — Posted on 2019-03-05 2843 Future ocean warming may prove beneficial for the northern population of European seabass, but ocean acidification does not Howald, S.; Cominassi, L.; Le Bayon, N.; Claireaux, G.; Mark, F. C. 10.1101/568428 — physiology — Posted on 2019-03-05 2844 Loss of one Engrailed1 allele enhances induced α-synucleinopathy Chatterjee, D.; Saiz Sanchez, D.; Quansah, E.; Rey, N. L.; George, S.; Becker, K.; Madaj, Z.; Steiner, J. A.; Ma, J.; Escobar Galvis, M. L.; Kordower, J. H.; Brundin, P. 10.1101/530915 — neuroscience — Posted on 2019-03-05 2845 Embryonic signals perpetuate polar-like trophoblast stem cells and pattern the blastocyst axis. Frias Aldeguer, J.; Kip, M.; Vivie, J.; Li, L.; Alemany, A.; Korving, J.; Darmis, F.; van Blitterswijk, C.; van Oudenaarden, A.; Geijsen, N.; Rivron, N. C. 10.1101/510362 — developmental biology — Posted on 2019-03-05 2846 Thiostrepton hijacks pyoverdine receptors to inhibit growth of Pseudomonas aeruginosa Ranieri, M. R. M.; Chan, D. C. K.; Yaeger, L. N.; Rudolph, M.; Kerabalas-Pittman, S.; Abdo, H.; Chee, J.; Harvey, H.; Nguyen, U.; Burrows, L. L. 10.1101/567990 — microbiology — Posted on 2019-03-05 2847 Genomic investigation reveals contaminated detergent as the source of an ESBL-producing Klebsiella michiganensis outbreak in a neonatal unit Chapman, P.; Forde, B.; Roberts, L. W.; Bergh, H.; Vasey, D.; Jennison, A. V.; Moss, S.; Paterson, D. L.; Beatson, S. A.; Harris, P. N. A. 10.1101/568154 — microbiology — Posted on 2019-03-05 2848 Low Mutational Load Allows for High Mutation Rate Variation in Gut Commensal Bacteria Ramiro, R. S.; Durao, P.; Bank, C.; Gordo, I. 10.1101/568709 — evolutionary biology — Posted on 2019-03-05 2849 A reformulation of the selection ratio shed light on resource selection functions and leads to a unified framework for habitat selection studies. Chamaille-Jammes, S. 10.1101/565838 — ecology — Posted on 2019-03-05 2850 The restoration species pool for restoring tropical landscapes: assessment of the largest Brazilian supply chain Vidal, C. Y.; Naves, R.; Viani, R. A. G.; Rodrigues, R. R. 10.1101/568873 — ecology — Posted on 2019-03-05 2851 The expendable male hypothesis Mattison, S.; Quinlan, R. J.; Hare, D. 10.1101/473942 — animal behavior and cognition — Posted on 2019-03-05 2852 Production of nonnatural straight chain amino acid 6-aminocaproate via an artificial recursive carbon-chain-extension cycle Cheng, J.; Song, T.; Zhou, X.; Torrens-Spence, M. P.; Wang, D.; Weng, J.-K.; Wang, Q. 10.1101/568121 — synthetic biology — Posted on 2019-03-05 2853 Characterizing and inferring quantitative cell cycle phase in single-cell RNA-seq data analysis Hsiao, C. J.; Tung, P.; Blischak, J. D.; Burnett, J.; Barr, K.; Dey, K. K.; Stephens, M.; Gilad, Y. 10.1101/526848 — genomics — Posted on 2019-03-05 2854 RAxML-NG: A fast, scalable, and user-friendly tool for maximum likelihood phylogenetic inference Kozlov, A.; Darriba, D.; Flouri, T.; Morel, B.; Stamatakis, A. 10.1101/447110 — bioinformatics — Posted on 2019-03-05 2855 A Comparison of Non-human Primate and Deep Reinforcement Learning Agent Performance in a Virtual Pursuit-Avoidance Task Willke, T. L.; Yoo, S. B. M.; Capota, M.; Musslick, S.; Hayden, B. Y.; Cohen, J. D. 10.1101/567545 — neuroscience — Posted on 2019-03-05 2856 Solving High-Resolution Forward Problems for Extra- and Intracranial Neurophysiological Recordings Using Boundary Element Fast Multipole Method Makarov, S. N.; Hämäläinen, M.; Okada, Y.; Noetscher, G.; Ahveninen, J.; Nummenmaa, A. 10.1101/567933 — neuroscience — Posted on 2019-03-05 2857 Corrective muscle activity reveals subject-specific sensorimotor recalibration. Iturralde, P. A.; Torres-Oviedo, G. 10.1101/372359 — neuroscience — Posted on 2019-03-05 2858 RexAB is essential for the mutagenic repair of Staphylococcus aureus DNA damage caused by co-trimoxazole Clarke, R. S.; Bruderer, M. S.; Ha, K. P.; Edwards, A. M. 10.1101/568196 — microbiology — Posted on 2019-03-05 2859 Stress-induced TFIIIC binding to Alu elements controls gene expression via chromatin looping and histone acetylation Ferrari, R.; Llobet Cucalon, L. I.; Di Vona, C.; Le Dilly, F.; Vidal, E.; Lioutas, A.; Oliete, J. Q.; Jochem, L.; Cutts, E.; Dieci, G.; Alessandro, V.; Teichmann, M.; de la Luna, S.; Beato, M. 10.1101/455733 — genomics — Posted on 2019-03-05 2860 Evolutionary superscaffolding and chromosome anchoring to improve Anopheles genome assemblies Waterhouse, R. M.; Aganezov, S.; Anselmetti, Y.; Lee, J.; Ruzzante, L.; Reijnders, M. J.; Feron, R.; Berard, S.; George, P.; Hahn, M. W.; Howell, P. I.; Kamali, M.; Koren, S.; Lawson, D.; Maslen, G.; Peery, A.; Phillippy, A. M.; Sharakhova, M. V.; Tannier, E.; Unger, M. F.; Zhang, S. V.; Alekseyev, M. A.; Besansky, N. J.; Chauve, C.; Emrich, S. J.; Sharakhov, I. V. 10.1101/434670 — genomics — Posted on 2019-03-05 2861 Amelioration of Brain Histone Methylopathies by Balancing a Writer-Eraser Duo KMT2A-KDM5C Vallianatos, C. N.; Raines, B.; Porter, R. S.; Wu, M.; Garay, P. M.; Collette, K. M.; Seo, Y. A.; Dou, Y.; Keegan, K.; Tronson, N.; Iwase, S. 10.1101/567917 — genetics — Posted on 2019-03-05 2862 Translational products encoded by novel ORFs may form protein-like structures and have biological functions Erady, C.; Chong, D.; Meena, N.; Puntambekar, S.; Chauhan, R.; Umrania, Y.; Andreani, A.; Nel, J.; Wayland, M.; Pina, C.; Lilley, K. S.; Prabakaran, S. 10.1101/567800 — genetics — Posted on 2019-03-05 2863 FST and the triangle inequality for biallelic markers Arbisser, I. M.; Rosenberg, N. A. 10.1101/567743 — evolutionary biology — Posted on 2019-03-05 2864 Genetic drift in range expansions is very sensitive to density feedback in dispersal and growth Birzu, G.; Matin, S.; Hallatschek, O.; Korolev, K. 10.1101/565986 — evolutionary biology — Posted on 2019-03-05 2865 Allostery in oligomeric receptor models Conradi Smith, G. D. 10.1101/330571 — biophysics — Posted on 2019-03-05 2866 ARBoR: An Identity and Security Solution for Clinical Reporting Venner, E.; Murugan, M.; Hale, W.; Jones, J.; Lu, S.; Yi, V.; Gibbs, R. A. 10.1101/567875 — bioinformatics — Posted on 2019-03-05 2867 An engineered monomer binding-protein for α-synucleinefficiently inhibits the proliferation of amyloid fibrils Agerschou, E. D.; Saridaki, T.; Flagmeier, P.; Galvagnion, C.; Komnig, D.; Nagpal, A.; Gasterich, N.; Heid, L.; Prasad, V.; Shaykhalishahi, H.; Voigt, A.; Willbold, D.; Dobson, C. M.; Falkenburger, B. H.; Hoyer, W.; Buell, A. K. 10.1101/568501 — bioengineering — Posted on 2019-03-05 2868 Network organization of antibody interactions in sequence and structure space: the RADARS model Prechl, J. 10.1101/438804 — immunology — Posted on 2019-03-05 2869 Evolutionary changes of an intestinal Lactobacillus reuteri during probiotic manufacture Lopez, L.; Cardenas, P. A.; Prado, M. B.; Trueba, G. 10.1101/567974 — evolutionary biology — Posted on 2019-03-05 2870 Mapping the human subcortical auditory system using histology, post mortem MRI and in vivo MRI at 7T Sitek, K. R.; Gulban, O. F.; Calabrese, E.; Johnson, G. A.; Ghosh, S. S.; de Martino, F. 10.1101/568139 — neuroscience — Posted on 2019-03-05 2871 Risk of multiple primary cancer diagnosis over age in families of Li-Fraumeni syndrome: a single institution perspective Shin, S. J.; Dodd, E. B.; Gao, F.; Bojadzieva, J.; Chen, J.; Kong, X.; Amos, C.; Ning, J.; Strong, L. C.; Wang, W. 10.1101/567693 — genetics — Posted on 2019-03-05 2872 Dispersal limitation and stage-specific local filtering processes vary with climate across a network of alpine grasslands Guittar, J.; Goldberg, D.; Klanderud, K.; Berge, A.; Boixaderas, M. R.; Meineri, E.; Topper, J.; Vandvik, V. 10.1101/567586 — ecology — Posted on 2019-03-05 2873 Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites. Basbous, J.; Aze, A.; Chaloin, L.; Lebdy, R.; Hodroj, D.; Ribeyre, C.; Larroque, M.; Shepard, C.; Kim, B.; Pruvost, A.; Moreaux, J.; Maiorano, D.; Mechali, M.; Constantinou, A. 10.1101/420893 — cancer biology — Posted on 2019-03-05 2874 Synthetic lethality screening reveals FDA-approved drugs that overcome ATP7B-mediated tolerance of tumor cells to cisplatin Mariniello, M.; Petruzzelli, R.; Wanderlingh, L.; La Montagna, R.; Carissimo, A.; Pane, F.; Amoresano, A.; Medina, D.; Polishchuk, R. 10.1101/568535 — cancer biology — Posted on 2019-03-05 2875 Clustering co-abundant genes identifies components of the gut microbiome that are reproducibly associated with colorectal cancer and inflammatory bowel disease Minot, S. S.; Willis, A. D. 10.1101/567818 — bioinformatics — Posted on 2019-03-05 2876 Metabolic Cost of Rapid Adaptation of Single Yeast Cells Under Unforeseen Challenge Woronoff, G.; Nghe, P.; Baudry, J.; Boitard, L.; Braun, E.; Griffiths, A. D.; Bibette, J. 10.1101/564419 — systems biology — Posted on 2019-03-05 2877 HILPDA uncouples lipid storage in adipose tissue macrophages from inflammation and metabolic dysregulation van Dierendonck, X. A. M. H.; de la Rosa Rodriguez, M. A.; Georgiadi, A.; Mattijssen, F.; Dijk, W.; van Weeghel, M.; Singh, R.; Borst, J. W.; Stienstra, R.; Kersten, S. 10.1101/566802 — physiology — Posted on 2019-03-05 2878 Mechanisms involved in follistatin-induced increased insulin action in skeletal muscle Han, X.; Moller, L. L. V.; De Groote, E.; Bojsen-Moller, K. K. N.; Davey, J.; Henriquez-Olguin, C.; Li, Z.; Knudsen, J. R.; Jensen, T. E.; Madsbad, S.; Gregorevic, P.; Richter, E. A.; Sylow, L. 10.1101/568097 — physiology — Posted on 2019-03-05 2879 Shared resources between visual attention and visual working memory are allocated through rhythmic sampling Balestrieri, E.; Ronconi, L.; Melcher, D. P. 10.1101/567602 — neuroscience — Posted on 2019-03-05 2880 Unexpected higher resilience to distraction during visual working memory in schizophrenia Zhao, Y.; Ran, X.; Zhang, L.; Zhang, R.; Ku, Y. 10.1101/567859 — neuroscience — Posted on 2019-03-05 2881 Looking forward does not mean forgetting about the past: ERP evidence for the interplay of predictive coding and interference during language processing Schoknecht, P.; Roehm, D.; Schlesewsky, M.; Bornkessel-Schlesewsky, I. 10.1101/567560 — neuroscience — Posted on 2019-03-05 2882 Multiple constrained minimum variance beamformer (MCMV) performance in connectivity analyses Nunes, A. N.; Moiseev, A.; Kozhemiako, N.; Cheung, T.; Ribary, U.; Doesburg, S. 10.1101/567768 — neuroscience — Posted on 2019-03-05 2883 Non-Invasive Assays of Cochlear Synaptopathy -- Candidates and Considerations Bharadwaj, H. M.; Mai, A. R.; Simpson, J. M.; Choi, I.; Heinz, M. G.; Shinn-Cunningham, B. G. 10.1101/565655 — neuroscience — Posted on 2019-03-05 2884 What the odor is not: Estimation by elimination Singh, V.; Tchernookov, M.; Balasubramanian, V. 10.1101/568626 — neuroscience — Posted on 2019-03-05 2885 Hippocampal volume across age: Nomograms derived from over 19,700 people in UK Biobank Nobis, L.; Manohar, S. G.; Smith, S. M.; Alfaro Almagro, F.; Jenkinson, M.; Mackay, C. E.; Husain, M. 10.1101/562678 — neuroscience — Posted on 2019-03-05 2886 MRI and cognitive scores complement each other to accurately predict Alzheimer’s dementia 2 to 7 years before clinical onset Zandifar, A.; Fonov, V.; Ducharme, S.; Belleville, S.; Collins, D. L. 10.1101/567867 — neuroscience — Posted on 2019-03-05 2887 Quantifying the efficiency and biases of forest Saccharomyces sampling strategies Boynton, P. J.; Kowallik, V.; Landermann, D.; Stukenbrock, E. H. 10.1101/559724 — microbiology — Posted on 2019-03-05 2888 HSV-1 single cell analysis reveals anti-viral and developmental programs activation in distinct sub-populations Drayman, N.; Patel, P.; Vistain, L.; Tay, S. 10.1101/566489 — microbiology — Posted on 2019-03-05 2889 Pacbio sequencing reveals identical organelle genomes between American cranberry (Vaccinium macrocarpon Ait.) and a wild relative Diaz-Garcia, L.; Rodriguez-Bonilla, L.; Smith, T.; Zalapa, J. 10.1101/567925 — genomics — Posted on 2019-03-05 2890 On the cross-population portability of gene expression prediction models Keys, K. L.; Mak, A. C. Y.; White, M. J.; Eckalbar, W.; Dahl, A. J.; Mefford, J.; Mikhaylova, A. V.; Contreras, M. G.; Elhawary, J. R.; Eng, C.; Hu, D.; Huntsman, S.; Oh, S. S.; Salazar, S.; Lenoir, M. A.; Ye, C. J.; Thornton, T. A.; Zaitlen, N.; Burchard, E. G.; Gignoux, C. R. 10.1101/552042 — genomics — Posted on 2019-03-05 2891 Adapterama I: Universal stubs and primers for 384 unique dual-indexed or 147,456 combinatorially-indexed Illumina libraries (iTru & iNext) Glenn, T. C.; Nilsen, R. A.; Kieran, T. J.; Sanders, J. G.; Bayona-Vasquez, N. J.; Finger, J. W.; Pierson, T. W.; Bentley, K. E.; Hoffberg, S. L.; Louha, S.; Garcia-De-Leon, F. J.; Angel del Rio Portilla, M.; Reed, K. D.; Anderson, J. L.; Meece, J. K.; Aggery, S. E.; Rekaya, R.; Alabady, M.; Belanger, M.; Winker, K.; Faircloth, B. C. 10.1101/049114 — genomics — Posted on 2019-03-05 2892 The phytopathogenic nature of Dickeya aquatica 174/2 and the dynamic early evolution of Dickeya pathogenicity Duprey, A.; Taib, N.; Leonard, S.; Garin, T.; Flandrois, J.-P.; Nasser, W.; Brochier-Armanet, C.; Reverchon, S. 10.1101/568105 — genomics — Posted on 2019-03-05 2893 Tissue-specific Hi-C analyses of rice, foxtail millet and maize suggest non-canonical function of plant chromatin domains Dong, P.; Tu, X.; Li, H.; Zhang, J.; Grierson, D.; Li, P.; zhong, s. 10.1101/567883 — genomics — Posted on 2019-03-05 2894 Risk of differential cancer types over age in families with Li-Fraumeni syndrome: a validation study using multi-center cohorts Shin, S. J.; Dodd, E.; Peng, G.; Bojadzieva, J.; Chen, J.; Amos, C.; Mai, P. L.; Savage, S. A.; Ballinger, M. L.; Thomas, D. M.; yuan, Y.; Strong, L. C.; Wang, W. 10.1101/567727 — genetics — Posted on 2019-03-05 2895 Analysis of factor V in zebrafish demonstrates minimal levels needed for hemostasis and risk stratifies human variants Weyand, A. C.; Grzegorski, S. J.; Rost, M. S.; Lavik, K. I.; Ferguson, A. C.; Menegatti, M.; Richter, C. E.; Asselta, R.; Duga, S.; Peyvandi, F.; Shavit, J. A. 10.1101/567453 — genetics — Posted on 2019-03-05 2896 Resistance diagnostics as a public health tool to combat antibiotic resistance: A model-based evaluation McAdams, D.; Wollein Waldetoft, K.; Tedijanto, C.; Lipsitch, M.; Brown, S. P. 10.1101/452656 — epidemiology — Posted on 2019-03-05 2897 Subtle, seasonal and potentially important: Are phytotoxic foliage leachates overlooked in plant invasion studies? Jones, G.; Tomlinson, M.; Owen, R.; Scullion, J.; Winters, A.; Jenkins, T.; Ratcliffe, J.; Gwynn-Jones, D. 10.1101/566976 — ecology — Posted on 2019-03-05 2898 Shifted distribution baselines: neglecting long-term biodiversity records risks overlooking potentially suitable habitat for conservation management Monsarrat, S.; Novellie, P.; Rushworth, I.; Kerley, G. I. H. 10.1101/565929 — ecology — Posted on 2019-03-05 2899 Field trial of a probiotic bacteria and a chemical, chitosan, to protect bats from white-nose syndrome Hoyt, J. R.; Langwig, K. E.; White, J. P.; Kaarakka, H. M.; Redell, J. A.; Parise, K. L.; Frick, W. F.; Foster, J. T.; Kilpatrick, A. M. 10.1101/567826 — ecology — Posted on 2019-03-05 2900 The UCSC Xena platform for public and private cancer genomics data visualization and interpretation Goldman, M.; Craft, B.; Hastie, M.; Repecka, K.; Kamath, A.; McDade, F.; Rogers, D.; Brooks, A. N.; Zhu, J.; Haussler, D. 10.1101/326470 — cancer biology — Posted on 2019-03-05 2901 Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma De Crignis, E.; Carofiglio, F.; Moulos, P.; Verstegen, M. M. A.; Romal, S.; Khalid, M. M.; Pourfarzad, F.; Koutsothanassis, C.; Gehart, H.; Kan, T. W.; Palstra, R.-J.; Boucher, C.; IJzermans, J.; Huch, M.; Boj, S.; Vries, R.; Clevers, H.; van der Laan, L.; Hatzis, P.; Mahmoudi, T. 10.1101/568147 — cancer biology — Posted on 2019-03-05 2902 A pressure sensing protein kinase Akella, R.; Sekulski, K.; Pleinis, J. M.; Liwocha, J.; Jiou, J.; He, H.; Humphreys, J. M.; Schellinger, J. N.; Joachimiak, L.; Rodan, A. R.; Goldsmith, E. J. 10.1101/435008 — biophysics — Posted on 2019-03-05 2903 GPseudoClust: deconvolution of shared pseudo-trajectories at single-cell resolution Strauss, M.; Kirk, P. D.; Reid, J. E.; Wernisch, L. 10.1101/567115 — bioinformatics — Posted on 2019-03-05 2904 Unsupervised Toxoplasma gondii Recognition by Fuzzy Cycle Generative Adversarial Network Li, S.; Li, A.; Lara, D. A. M.; Gomez Marin, J. E.; Zhang, Y. 10.1101/567891 — bioinformatics — Posted on 2019-03-05 2905 Integrating deep and radiomics features in cancer bioimaging Bizzego, A.; Bussola, N.; Salvalai, D.; Chierici, M.; Maggio, V.; Jurman, G.; Furlanello, C. 10.1101/568170 — bioinformatics — Posted on 2019-03-05 2906 Mechanics of wood boring by beetle mandibles Kundanati, L.; Chahare, N. R.; Jaddivada, S.; Karkisaval, A. G.; Pugno, N. M.; Gundiah, N. 10.1101/568089 — bioengineering — Posted on 2019-03-05 2907 Identification of novel glycosylation events on human serum-derived Factor IX Pegg, C. L.; Zacchi, L. F.; Roche Recinos, D.; Howard, C. B.; Schulz, B. L. 10.1101/567941 — biochemistry — Posted on 2019-03-05 2908 Sex and age don’t matter but breed type does - Factors influencing eye wrinkle expression in horses Schanz, L.; Krueger, K.; Hintze, S. 10.1101/567149 — animal behavior and cognition — Posted on 2019-03-05 2909 Towards an individualised neural assessment of receptive language in children Petit, S.; Badcock, N. A.; Grootswagers, T.; Rich, A. N.; Brock, J.; Nickels, L.; Moerel, D.; Dermody, N.; Yau, S.; Schmidt, E.; Woolgar, A. 10.1101/566752 — animal behavior and cognition — Posted on 2019-03-05 2910 A decade of empirical research on research integrity: what have we (not) looked at? Aubert Bonn, N.; Pinxten, W. 10.1101/567263 — scientific communication and education — Posted on 2019-03-05 2911 Application of Global Metabolomics to the Identification of Complex Counterfeit Medicinal Products Jenkins, C.; Orsburn, B. 10.1101/567339 — pharmacology and toxicology — Posted on 2019-03-05 2912 Retinal and Cortical Determinants of Cortical Magnification in Human Albinism Woertz, E. N.; Wilk, M. A.; Duwell, E.; Mathis, J.; Carroll, J.; DeYoe, E. A. 10.1101/562249 — neuroscience — Posted on 2019-03-05 2913 The neurofunctional basis of affective startle modulation in humans - evidence from combined facial EMG-fMRI Kuhn, M.; Wendt, J.; Sjouwerman, R.; Büchel, C.; Hamm, A.; Lonsdorf, T. B. 10.1101/567032 — neuroscience — Posted on 2019-03-05 2914 Dynamics of dual specificity phosphatases and their interplay with protein kinases in immune signaling Subbannayya, Y.; Pinto, S.; Bosl, K.; Prasad, T. S. K.; Kandasamy, R. K. 10.1101/568576 — immunology — Posted on 2019-03-05 2915 Genomic architecture of phenotypic plasticity of complex traits in tetraploid wheat in response to water stress Fatiukha, A.; Deblieck, M.; Klymiuk, V.; Merchuk-Ovnat, L.; Peleg, Z.; Ordon, F.; Fahima, T.; Saranga, A. B.; Saranga, Y.; Krugman, T. 10.1101/565820 — genetics — Posted on 2019-03-05 2916 Improved HLA-based prediction of coeliac disease identifies two novel HLA risk modifiers, DQ6.2 and DQ7.3 Erlichster, M.; Bedo, J.; Skafidas, E.; Kwan, P.; Kowalczyk, A.; Goudey, B. 10.1101/561308 — genetics — Posted on 2019-03-05 2917 An R Implementation of Tumor-Stroma-Immune Transcriptome Deconvolution Pipeline using DeMixT Cao, S.; Wang, Z.; Gao, F.; Chen, J.; Zhang, F.; Frigo, D. E.; Efstathiou, E.; Kopetz, S.; Wang, W. 10.1101/566075 — bioinformatics — Posted on 2019-03-05 2918 The Tangent copy-number inference pipeline for cancer genome analyses Tabak, B.; Saksena, G.; Oh, C.; Gao, G. F.; Hill Meyers, B.; Reich, M.; Schumacher, S. E.; Westlake, L. C.; Berger, A. C.; Carter, S. L.; Cherniack, A. D.; Meyerson, M.; Beroukhim, R.; Getz, G. 10.1101/566505 — bioinformatics — Posted on 2019-03-05 2919 EPIC: MHC-I epitope prediction integrating mass spectrometry derived motifs and tissue-specific expression profiles Hu, W.; Qiu, S.; Li, Y.; Lin, X.; Zhang, L.; Xiang, H.; Han, X.; Chen, L.; Li, S.; Li, W.; Ren, Z.; Hou, G.; Lin, Z.; Lu, J.; Liu, G.; Li, B.; Lee, L. 10.1101/567081 — bioinformatics — Posted on 2019-03-05 2920 Comprehensive analysis of the internal structure and firmness in American cranberry (Vaccinium macrocarpon Ait.) fruit Diaz-Garcia, L.; Rodriguez-Bonilla, L.; Phillips, M.; Lopez-Hernandez, A.; Grygleski, E.; Atucha, A.; Zalapa, J. 10.1101/567958 — plant biology — Posted on 2019-03-05 2921 Plant photoreceptors and their signaling components compete for binding to the ubiquitin ligase COP1 using their VP-peptide motifs Lau, K.; Podolec, R.; Chappuis, R.; Ulm, R.; Hothorn, M. 10.1101/568618 — plant biology — Posted on 2019-03-05 2922 DNA sequence differences and temperature are determinants of meiotic recombination outcome Brown, S. D.; Asogwa, M. N.; Jezequel, M.; Charlotte, A.; Mpaulo, S. J.; Whitby, M. C.; Lorenz, A. 10.1101/568543 — genetics — Posted on 2019-03-05 2923 Evaluating genomic data for management of local adaptation in a changing climate: A lodgepole pine case study Mahony, C. R.; MacLachlan, I. R.; Lind, B. M.; Yoder, J. B.; Wang, T.; Aitken, S. N. 10.1101/568725 — evolutionary biology — Posted on 2019-03-05 2924 Effect of time-series length and resolution on abundance- and trait-based early warning signals of population declines Arkilanian, A.; Clements, C. F.; Ozgul, A.; Baruah, G. 10.1101/568600 — ecology — Posted on 2019-03-05 2925 Molecular Correlations between Breast Cancer and Diabetes Mellitus Type 2 Examined by In Silico analyses and Drug Inhibitory Effects Afzali, F.; Nayeri, Z.; Minuchehr, Z.; Gardaneh, M. 10.1101/568634 — cancer biology — Posted on 2019-03-05 2926 Network-based approaches elucidate differences within APOBEC and clock-like signatures in breast cancer Kim, Y.-A.; Wojtowicz, D.; Sarto Basso, R.; Sason, I.; Robinson, W.; Hochbaum, D. S.; Leiserson, M. D. M.; Sharan, R.; Vandin, F.; Przytycka, T. M. 10.1101/568568 — bioinformatics — Posted on 2019-03-05 2927 An Integrated Chemical Proteomics Approach for Quantitative Profiling of Intracellular ADP-Ribosylation Kalesh, K.; Lukauskas, S.; Borg, A. J.; Snijders, A. P.; Leung, A. K. L.; Haskard, D. O.; DiMaggio, P. A. 10.1101/568527 — biochemistry — Posted on 2019-03-05 2928 Bioisosterism reveals new structure-odor relationships Tahirova, N.; Poivet, E.; Xu, L.; Peterlin, Z.; Zou, D.-J.; Firestein, S. 10.1101/567701 — neuroscience — Posted on 2019-03-05 2929 Content-based dissociation of hippocampal involvement in prediction Kok, P.; Rait, L. I.; Turk-Browne, N. B. 10.1101/568303 — neuroscience — Posted on 2019-03-05 2930 Neural precursors of decisions that matter--an ERP study of deliberate and arbitrary choice Maoz, U.; Yaffe, G.; Koch, C.; Mudrik, L. 10.1101/097626 — neuroscience — Posted on 2019-03-05 2931 Detection of Base Analogs Incorporated During DNA Replication by Nanopore Sequencing Georgieva, D.; Liu, Q.; Wang, K.; Egli, D. 10.1101/549220 — genomics — Posted on 2019-03-05 2932 Increasing the value of raw bulk milk quality based on mammary glands as production units vs. the udder in dairy cows with mastitis Leitner, G.; Lavon, Y.; Merin, U.; Jacoby, S.; Blum, S. E.; Krifucks, O.; Silanikove, N. 10.1101/567271 — systems biology — Posted on 2019-03-05 2933 StomataCounter: a neural network for automatic stomata identification and counting. Fetter, K. C.; Eberhardt, S.; Barclay, R. S.; Wing, S.; Keller, S. R. 10.1101/327494 — plant biology — Posted on 2019-03-05 2934 A model of the entrance pupil of the human eye Aguirre, G. K. 10.1101/325548 — neuroscience — Posted on 2019-03-05 2935 Evaluating fMRI-Based Estimation of Eye Gaze during Naturalistic Viewing Son, J.; Ai, L.; Lim, R.; Xu, T.; Colcombe, S.; Franco, A.; Cloud, J.; LaConte, S.; Lisinski, J.; Klein, A.; Craddock, C.; Milham, M. 10.1101/347765 — neuroscience — Posted on 2019-03-05 2936 A Tale of Two Positivities and the N400: Distinct neural signatures are evoked by confirmed and violated predictions at different levels of representation Kuperberg, G.; Brothers, T.; Wlotko, E. 10.1101/404780 — neuroscience — Posted on 2019-03-05 2937 Adapterama III: Quadruple-indexed, double/triple-enzyme RADseq libraries (2RAD/3RAD) Bayona-Vasquez, N. J.; Glenn, T. C.; Kieran, T. J.; Pierson, T. W.; Hoffberg, S. L.; Scott, P. A.; Bentley, K. E.; Finger, J. W.; Louha, S.; Troendle, N.; Diaz-Jaimes, P.; Mauricio, R.; Faircloth, B. C. 10.1101/205799 — genomics — Posted on 2019-03-05 2938 Content of and interactions between repetitive elements in programmatically eliminated chromosomes of the sea lamprey (Petromyzon marinus) Timoshevskiy, V. A.; Timoshevskaya, N. Y.; Smith, J. J. 10.1101/567370 — genetics — Posted on 2019-03-05 2939 Bayesian arrival model for Atlantic salmon smolt counts powered by environmental covariates and expert knowledge Pulkkinen, H.; Orell, P.; Erkinaro, J.; Mantyniemi, S. 10.1101/399618 — ecology — Posted on 2019-03-05 2940 Impacts of climate change on high priority fruit fly species in Australia Sultana, S.; Baumgartner, J. B.; Dominiak, B. C.; Royer, J. E.; Beaumont, L. J. 10.1101/567321 — ecology — Posted on 2019-03-05 2941 GVC: A superfast and universal genomic variant caller Zhang, Z.; Yin, L.; hao, l.; Cao, L.; Liu, C.; Chen, M.; Li, C.; Xu, Z.; Ling, S. 10.1101/182089 — bioinformatics — Posted on 2019-03-05 2942 Genome-wide association analysis of 350,000 Caucasians from the UK Biobank identifies novel loci for asthma, hay fever and eczema. Johansson, A.; Rask-Andersen, M.; Karlsson, T.; Ek, W. E. 10.1101/195933 — genetics — Posted on 2019-03-05 2943 Ancestry-specific association mapping in admixed populations Skotte, L.; Jorsboe, E.; Korneliussen, T. S.; Moltke, I.; Albrechtsen, A. 10.1101/014001 — genetics — Posted on 2019-03-05 2944 Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation Price, A. J.; Hwang, T.; Tao, R.; Burke, E. E.; Rajpurohit, A.; Shin, J.; Hyde, T. M.; Kleinman, J. E.; Jaffe, A. E.; Weinberger, D. 10.1101/567966 — neuroscience — Posted on 2019-03-05 2945 Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections Pauli, M.; Paul, M. M.; Proppert, S.; Sharifi, M.; Repp, F.; Kollmannsberger, P.; Sauer, M.; Heckmann, M.; Siren, A.-L. 10.1101/568279 — neuroscience — Posted on 2019-03-05 2946 Heterozygous variants in KMT2E cause a spectrum of neurodevelopmental disorders and epilepsy O'Donnell-Luria, A. H.; Pais, L. S.; Faundes, V.; Wood, J. C.; Sveden, A.; Luria, V.; Abou Jamra, R.; Accogli, A.; Amburgey, K.; Anderlid, B.-M.; Azzarello-Burri, S.; Basinger, A. A.; Bianchini, C.; Bird, L. M.; Buchert, R.; Carre, W.; Ceulemans, S.; Charles, P.; Cox, H.; Culliton, L.; Curro, A.; Deciphering Developmental Disorders (DDD) Study, ; Demurger, F.; Dowling, J. J.; Duban-Bedu, B.; Dubourg, C.; Escobar, L. F.; Ferrarini, A.; Haack, T. B.; Hashim, M.; Heide, S.; Helbig, K. L.; Helbig, I.; Heredia, R.; Heron, D.; Isidor, B.; Jonasson, A. R.; Joset, P.; Keren, B.; Kok, F.; Kroes, H. Y 10.1101/566091 — genetics — Posted on 2019-03-05 2947 About samples, giving examples: Optimized Single Molecule Localization Microscopy Jimenez, A.; Friedl, K.; Leterrier, C. 10.1101/568295 — cell biology — Posted on 2019-03-05 2948 Chronic unpredictable stress promotes cell-specific plasticity in prefrontal cortex D1 and D2 pyramidal neurons Anderson, E.; Gomez, D.; Caccamise, A.; McPhail, D.; Hearing, M. 10.1101/565499 — neuroscience — Posted on 2019-03-05 2949 Decoding mouse behavior to explain single-trial decisions and their relationship with neural activity. Weissenberger, Y.; King, A. C.; Dahmen, J. J. 10.1101/567479 — neuroscience — Posted on 2019-03-05 2950 Arabidopsis phytochelatin synthase 1, but not phytochelatin synthesis, functions in extracellular defense against multiple fungal pathogens Hematy, K.; Lim, M.; Cherk, C.; Bednarek, P.; Pislewska-Bednarek, M.; Sanchez-Rodriguez, C.; Stein, M.; Fuchs, R.; Klapprodt, C.; Lipka, V.; Molina, A.; Grill, E.; Schulze-Lefert, P.; Somerville, S. 10.1101/568113 — plant biology — Posted on 2019-03-05 2951 Plant-soil feedback contributes to predicting plant invasiveness of 68 alien plant species differing in invasive status Aldorfova, A.; Knobova, P.; Munzbergova, Z. 10.1101/568048 — plant biology — Posted on 2019-03-05 2952 Time course of the physiological stress response to an acute stressor and its associations with the primacy and recency effect of the serial position curve Becker, L.; Rohleder, N. 10.1101/568352 — physiology — Posted on 2019-03-05 2953 Kinematics associated with treadmill walking in Rett Syndrome Layne, C. S.; Young, D. R.; Lee, B.-C.; Glaze, D. G.; Schwabe, A.; Suter, B. 10.1101/568360 — neuroscience — Posted on 2019-03-05 2954 Global assessment of Mycobacterium avium subspecies hominissuis genetic requirement for growth and virulence. Dragset, M. S.; Ioerger, T. R.; Loevenich, M.; Haug, M.; Sivakumar, N.; Marstad, A.; Cardona, P. J.; Klinkenberg, G.; Rubin, E. J.; Steigedal, M.; Flo, T. H. 10.1101/568477 — microbiology — Posted on 2019-03-05 2955 The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection Vornhagen, J.; Sun, Y.; Breen, P.; Forsyth, V.; Zhao, L.; Mobley, H. L. T.; Bachman, M. A. 10.1101/568493 — microbiology — Posted on 2019-03-05 2956 HIV-1 co-receptor usage and variable loop contact impacts V3 loop bnAb susceptibility Registre, L.; Moreau, Y.; Toksoz Ataca, S.; Pulukuri, S.; Henrich, T. J.; Lin, N.; Sagar, M. 10.1101/568469 — microbiology — Posted on 2019-03-05 2957 Perinatal features of Prader-Willi syndrome: a Chinese cohort Yang, L.; Zhou, Q.; Ma, B.; Mao, S.; Dai, Y.; Zhu, M.; ZOU, C.-C. 10.1101/568451 — genetics — Posted on 2019-03-05 2958 Impact of an intra-abdominal cooling device during open kidney transplantation in pigs Longchamp, A.; Meier, R. P. H.; Colucci, N.; Balaphas, A.; Orci, L.; Nastasi, A.; Longchamp, G.; Moll, S.; Klauser, A.; Pascual, M.; Lazeyras, F.; Corpataux, J.-M.; Bühler, L. 10.1101/568402 — physiology — Posted on 2019-03-05 2959 Functional dissection of TADs reveals non-essential and instructive roles in regulating gene expression Despang, A.; Schöpflin, R.; Franke, M.; Ali, S.; Jerkovic, I.; Paliou, C.; Chan, W.-L.; Timmermann, B.; Wittler, L.; Vingron, M.; Mundlos, S.; Ibrahim, D. M. 10.1101/566562 — genetics — Posted on 2019-03-05 2960 Towards a further understanding of measles vaccine hesitancy in Khartoum state, Sudan: A qualitative study Sabahelzain, M. M.; Moukhyer, M.; Dube, E.; Hardan, A.; Bosma, H.; van den Borne, B. 10.1101/568345 — epidemiology — Posted on 2019-03-05 2961 Niche partitioning and coexistence of two spiders of the genus Peucetia (Araneae, Oxyopidae) inhabiting Trichogoniopsis adenantha plants (Asterales, Asteraceae): a population approach Villanueva, G. A.; Safuan-Naide, S.; Pires, M.; Vasconcellos-Neto, J. 10.1101/568410 — ecology — Posted on 2019-03-05 2962 Midgut Transcriptome Analysis of Clostera anachoreta Treated with Cry1Ac Toxin Liu, J.; Gao, B.; Wang, L.; Zhou, G.; Liu, J. 10.1101/568337 — zoology — Posted on 2019-03-05 2963 The Arabian camel, Camelus dromedarius interferon epsilon: functional expression, in vitro refolding, purification and cytotoxicity on breast cancer cell lines MDA-MB-231 and MCF-7 Saeed, H.; Abdelfattah, M.; El-Shennawy, L.; Shalaby, M.; Embaby, A.; Ataya, F.; Eed, H.; Hussein, A. 10.1101/568329 — molecular biology — Posted on 2019-03-05 2964 Human antiviral protein MxA forms novel metastable membrane-less cytoplasmic condensates exhibiting rapid reversible \"crowding\"-driven phase transitions Davis, D.; Yuan, H.; Liang, F.-X.; Yang, Y.-M.; Westley, J.; Petzold, C.; Dancel-Manning, K.; Deng, Y.; Sall, J.; Sehgal, P. B. 10.1101/568006 — cell biology — Posted on 2019-03-05 2965 NMDA receptors enhance the fidelity of synaptic integration Li, C.; Baker, A. L.; Gulledge, A. T. 10.1101/566117 — neuroscience — Posted on 2019-03-05 2966 Targeting the mTORC2 signaling complex in B cell malignancies. Liao, W.; Jordaan, G.; Benavides-Serrato, A.; Holmes, B.; Gera, J.; Sharma, S. 10.1101/564500 — cancer biology — Posted on 2019-03-05 2967 Carbon stocks of coastal seagrass in Southeast Asia may be far lower than anticipated when accounting for black carbon Gallagher, J. B.; Chuan, C. H.; Yap, T. K.; Farahain, W. 10.1101/493262 — plant biology — Posted on 2019-03-05 2968 A genetic link between leaf carbon isotope composition and whole-plant water use efficiency in the C4 grass Setaria Ellsworth, P.; Feldman, M.; Baxter, I.; Cousins, A. 10.1101/285676 — plant biology — Posted on 2019-03-05 2969 Enduring and sex-specific changes in hippocampal gene expression after a subchronic immune challenge Tchessalova, D.; Tronson, N. C. 10.1101/566570 — neuroscience — Posted on 2019-03-05 2970 Network resonance during slow-wave sleep facilitates memory consolidation through phase-coding Skilling, Q.; Clawson, B. C.; Eniwaye, B.; Shaver, J.; Ognjanovski, N.; Atan, S. J.; Zochowski, M. 10.1101/565242 — neuroscience — Posted on 2019-03-05 2971 Shared neural underpinnings of multisensory integration and trial-by-trial perceptual recalibration Park, H.; Kayser, C. 10.1101/566927 — neuroscience — Posted on 2019-03-05 2972 Supporting global biodiversity assessment through high-resolution macroecological modelling: Methodological underpinnings of the BILBI framework Hoskins, A. J.; Harwood, T. D.; Ware, C.; Williams, K. J.; Perry, J. J.; Ota, N.; Croft, J. R.; Yeates, D. K.; Jetz, W.; Golebiewski, M.; Purvis, A.; Ferrier, S. 10.1101/309377 — ecology — Posted on 2019-03-05 2973 Pluripotency factors regulate the onset of Hox cluster activation in the early embryo Lopez-Jimenez, E.; Sainz de Aja, J.; Badia-Careaga, C.; Barral, A.; Rollan, I.; Rouco, R.; Santos, E.; Tiana, M.; Victorino, J.; Sanchez-Iranzo, H.; Acemel, R. D.; Torroja, C.; Adan, J.; Andres-Leon, E.; Gomez-Skarmeta, J. L.; Giovinazzo, G.; Sanchez-Cabo, F.; Manzanares, M. 10.1101/564658 — developmental biology — Posted on 2019-03-05 2974 Syndecan-1 facilitates breast cancer metastasis to the brain Sayyad, M. R.; Puchalapalli, M.; Vergara, N. G.; Mosticone Wangensteen, S.; Moore, M.; Mu, L.; Edwards, C.; Anderson, A.; Kall, S.; Sullivan, M.; Dozmorov, M.; Singh, J.; Idowu, M. O.; Koblinski, J. E. 10.1101/565648 — cancer biology — Posted on 2019-03-05 2975 Non-responder phenotype reveals microbiome-wide antibiotic resistance in the murine gut Diener, C.; Hoge, A. C.; Kearney, S. M.; Edman, S. E.; Gibbons, S. M. 10.1101/566190 — systems biology — Posted on 2019-03-04 2976 A Monte Carlo method for in silico modeling and visualization of Waddington’s epigenetic landscape with intermediate details Zhang, X.; Chong, K. H.; Zheng, J. 10.1101/310771 — systems biology — Posted on 2019-03-04 2977 Experimental Assessment of PCR Specificity and Copy Number for Reliable Data Retrieval in DNA Storage Organick, L. W.; Chen, Y.-J.; Dumas Ang, S.; Lopez, R.; Strauss, K.; Ceze, L. 10.1101/565150 — synthetic biology — Posted on 2019-03-04 2978 Redundant SCARECROW genes pattern distinct cell layers in roots and leaves of maize Hughes, T. E.; Sedelnikova, O. V.; Wu, H.; Becraft, P. W.; Langdale, J. A. 10.1101/567156 — plant biology — Posted on 2019-03-04 2979 Induction of the nicotinamide riboside kinase NAD+ salvage pathway in skeletal muscle of H6PDH KO mice Doig, C. L.; Zelinska, A.; Oakey, L.; Fletcher, R.; El Hassan, Y.; Garten, A.; Cartwright, D.; Heising, S.; Tennant, D.; Watson, D.; Adamski, J.; Lavery, G. 10.1101/567297 — physiology — Posted on 2019-03-04 2980 FUS ALS-causative mutations impact FUS autoregulation and the processing of RNA-binding proteins through intron retention Humphrey, J.; Birsa, N.; Milioto, C.; Robaldo, D.; Bentham, M.; Jarvis, S.; Bodo, C.; Garone, M. G.; Devoy, A.; Rosa, A.; Bozzoni, I.; Fisher, E.; Ruepp, M.-D.; Schiavo, G.; Isaacs, A.; Plagnol, V.; Fratta, P. 10.1101/567735 — neuroscience — Posted on 2019-03-04 2981 Hidden neural states underlie canary song syntax Cohen, Y.; Shen, J.; Semu, D.; Leman, D. P.; Liberti, W. A.; Perkins, N. L.; Liberti, D. C.; Kotton, D.; Gardner, T. J. 10.1101/561761 — neuroscience — Posted on 2019-03-04 2982 Somatostatin-Expressing Interneurons Co-Release GABA and Glutamate onto Different Postsynaptic Targets in the Striatum. Cattaneo, S.; Zaghi, M.; Ripamonti, M.; Bedogni, F.; Sessa, A.; Taverna, S. 10.1101/566984 — neuroscience — Posted on 2019-03-04 2983 Loss of tau and Fyn reduces compensatory effects of MAP2 for tau and reveals a Fyn-independent effect of tau on glutamate-induced Ca2+ response Liu, G.; Thangavel, R.; Rysted, J.; Kim, Y.; Francis, M. B.; Adams, E.; Lin, Z.; Taugher, R. J.; Wemmie, J. A.; Usachev, Y. M.; Lee, G. 10.1101/567776 — neuroscience — Posted on 2019-03-04 2984 Differential effects of diet and weight on taste responses in diet-induced obese mice Ahart, Z. C.; Martin, L. E.; Kemp, B. R.; Dutta Banik, D.; Roberts, S. G. E.; Torregrossa, A. M.; Medler, K. 10.1101/564211 — neuroscience — Posted on 2019-03-04 2985 Interaction of modified oligonucleotides with nuclear proteins, formation of novel nuclear structures and sequence-independent effects on RNA processing Flynn, L. L.; Li, R.; Aung-Htut, M. T.; Pitout, I. L.; Cooper, J. A. L.; Hubbard, A.; Griffiths, L.; Bond, C.; Wilton, S. D.; Fox, A. H.; Fletcher, S. 10.1101/446773 — molecular biology — Posted on 2019-03-04 2986 Identification of RBPMS as a smooth muscle master splicing regulator via proximity of its gene with super-enhancers Nakagaki-Silva, E. E.; Gooding, C.; Llorian, M.; Jacob, A. G.; Richards, F.; Buckroyd, A.; Sinha, S.; Smith, C. W. 10.1101/563304 — molecular biology — Posted on 2019-03-04 2987 A hidden battle in the dirt: soil amoebae interactions with Paracoccidioides spp Albuquerque, P.; Nicola, A. M.; Magnabosco, D. A. G.; Derengowski, L. d. S.; Crisostomo, L. S.; Xavier, L. C. G.; Frazao, S. O.; Guilhelmelli, F.; Oliveira, M. A.; Hurtado, F. A.; Teixeira, M. M.; Guimaraes, A. J.; Paes, H. C.; Bagagli, E.; Felipe, M. S. S.; Casadevall, A.; Silva-Pereira, I. 10.1101/564435 — microbiology — Posted on 2019-03-04 2988 Environmental plasticity and colonisation history in the Atlantic salmon microbiome: a translocation experiment Uren Webster, T.; Rodriguez Barreto, D.; Castaldo, G.; Gough, P.; Consuegra, S.; Garcia de Leaniz, C. 10.1101/564104 — microbiology — Posted on 2019-03-04 2989 Modulation of Flagellar Rotation in Surface-Attached Bacteria: A Circuit for Rapid Surface-Sensing Schniederberend, M.; Johnston, J. F.; Shine, E. E.; Shen, C.; Jain, R.; Emonet, T.; Kazmierczak, B. 10.1101/567438 — microbiology — Posted on 2019-03-04 2990 Pan-viral protection against arboviruses by targeting inoculation site-based skin macrophages Bryden, S. R.; Pingen, M.; Lefteri, D. R.; Major, J.; Delang, L.; Jacobs, S.; Abdelnabi, R.; Neyts, J.; Miltenburg, J.; Khalid, H.; Tuplin, A.; Merits, A.; Pondeville, E.; Edgar, J.; Graham, G. J.; Shams, K.; McKimmie, C. 10.1101/566885 — immunology — Posted on 2019-03-04 2991 Gene expression profiles and pathway enrichment analysis to identification of differentially expressed gene and signaling pathways in epithelial ovarian cancer based on high-throughput RNA-seq data siavoshi, A.; Taghizadeh, M.; Dookhe, E.; Piran, M. 10.1101/566331 — genomics — Posted on 2019-03-04 2992 Hierarchical clustering of gene-level association statistics reveals shared and differential genetic architecture among traits in the UK Biobank McGuirl, M. R.; Smith, S. P.; Sandstede, B.; Ramachandran, S. 10.1101/565903 — genomics — Posted on 2019-03-04 2993 Genes essential for embryonic stem cells are associated with neurodevelopmental disorders Shohat, S.; Shifman, S. 10.1101/567073 — genomics — Posted on 2019-03-04 2994 A robust and efficient method for Mendelian randomization with hundreds of genetic variants: unravelling mechanisms linking HDL-cholesterol and coronary heart disease Burgess, S.; Foley, C. N.; Allara, E.; Staley, J. R.; Howson, J. M. 10.1101/566851 — genetics — Posted on 2019-03-04 2995 The nonlinear structure of linkage disequilibrium Smith, R. D. 10.1101/566208 — genetics — Posted on 2019-03-04 2996 Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases Soskic, B.; Cano Gamez, E.; Smith, D. J.; Rowan, W. C.; Nakic, N.; Esparza-Gordillo, J.; Bossini-Castillo, L.; Tough, D. F.; Larminie, C. G. C.; Bronson, P. G.; Wille, D.; Trynka, G. 10.1101/566810 — genetics — Posted on 2019-03-04 2997 Mutation profiling of both cfDNAs and CTCs in gynecological cancer patients Lee, S.-Y.; Chae, D.-k.; An, J.; Jung, S.; Bhak, J.; Kim, B. C.; Cho, D.-H. 10.1101/566786 — genetics — Posted on 2019-03-04 2998 Major QTLs for resistance to early and late leaf spot diseases are identified on chromosomes 3 and 5 in peanut (Arachis hypogaea) Chu, Y.; Chee, P.; Culbreath, A. K.; Isleib, T. G.; Holbrook, C. C.; Ozias-Akins, P. 10.1101/567206 — genetics — Posted on 2019-03-04 2999 The role of insulators in transgene transvection in Drosophila Piwko, P.; Vitsaki, I.; Livadaras, I.; Delidakis, C. 10.1101/565846 — genetics — Posted on 2019-03-04 3000 SimRVSequences: an R package to simulate genetic sequence data for pedigrees Nieuwoudt, C.; Brooks-Wilson, A.; Graham, J. 10.1101/534552 — genetics — Posted on 2019-03-04 3001 Genomic Bayesian confirmatory factor analysis and Bayesian network to characterize a wide spectrum of rice phenotypes Yu, H.; Campbell, M. T.; Zhang, Q.; Walia, H.; Morota, G. 10.1101/435792 — genetics — Posted on 2019-03-04 3002 From root to tips: sporulation evolution and specialization in Bacillus subtilis and the intestinal pathogen Clostridioides difficile Ramos-Silva, P.; Serrano, M.; Henriques, A. O. 10.1101/473793 — evolutionary biology — Posted on 2019-03-04 3003 Testing for correlation between traits under directional evolution Royer-Carenzi, M.; Didier, G. 10.1101/566349 — evolutionary biology — Posted on 2019-03-04 3004 Ant collective behavior is heritable and shaped by selection Walsh, J. T.; Garnier, S.; Linksvayer, T. A. 10.1101/567503 — evolutionary biology — Posted on 2019-03-04 3005 Role of α-Catenin and its mechanosensing properties in the regulation of Hippo/YAP-dependent tissue growth Sarpal, R.; Yan, V.; Kazakova, L.; Sheppard, L.; Tepass, U. 10.1101/567750 — cell biology — Posted on 2019-03-04 3006 A Cryo-EM Grid Preparation Device for Time-Resolved Structural Studies Kontziampasis, D.; Klebl, D. P.; Iadanza, M. G.; Scarff, C. A.; Kopf, F.; Sobott, F.; Monteiro, D. C. F.; Trebbin, M.; Muench, S. P.; White, H. D. 10.1101/563254 — biophysics — Posted on 2019-03-04 3007 A high-resolution pipeline for 16S-sequencing identifies bacterial strains in human microbiome Segota, I.; Long, T. 10.1101/565572 — bioinformatics — Posted on 2019-03-04 3008 Nebula: Ultra-efficient mapping-free structural variant genotyper Khorsand, P.; Hormozdiari, F. 10.1101/566620 — bioinformatics — Posted on 2019-03-04 3009 Machine-learning a virus assembly fitness landscape Dechant, P.-P.; He, Y.-H. 10.1101/567610 — bioinformatics — Posted on 2019-03-04 3010 Biological Filtering and Substrate Promiscuity Prediction for Annotating Untargeted Metabolomics Hassanpour, N.; Alden, N.; Menon, R.; Jayaraman, A.; Lee, K.; Hassoun, S. 10.1101/558973 — bioengineering — Posted on 2019-03-04 3011 The reactivity of an unusual amidase may explain colibactin’s DNA cross-linking activity Jiang, Y.; Stornetta, A.; Villalta, P. W.; Wilson, M. R.; Boudreau, P. D.; Zha, L.; Balbo, S.; Balskus, E. P. 10.1101/567248 — biochemistry — Posted on 2019-03-04 3012 Integrating behaviour and ecology into global biodiversity conservation strategies Tobias, J. A.; Pigot, A. L. 10.1101/566406 — animal behavior and cognition — Posted on 2019-03-04 3013 Inter-individual and inter-strain differences in cognitive and social abilities of Dark Agouti and Wistar Han rats Alonso, L.; Peeva, P.; Ramos-Prats, A.; Alenina, N.; Winter, Y.; Rivalan, M. 10.1101/566877 — animal behavior and cognition — Posted on 2019-03-04 3014 Single-cell RNA-sequencing of Herpes simplex virus 1-infected cells identifies NRF2 activation as an antiviral program Wyler, E.; Franke, V.; Menegatti, J.; Kocks, C.; Boltengagen, A.; Praktiknjo, S.; Walch-Rueckheim, B.; Rajewsky, N.; Graesser, F.; Akalin, A.; Landthaler, M. 10.1101/566992 — systems biology — Posted on 2019-03-04 3015 Polychromatic solar energy conversion in pigment-protein chimeras that unite the two kingdoms of (bacterio)chlorophyll-based photosynthesis Liu, J.; Friebe, V. M.; Frese, R. N.; Jones, M. R. 10.1101/565283 — synthetic biology — Posted on 2019-03-04 3016 Reconstructing the ecology of a Jurassic pseudoplanktonic megaraft colony Hunter, A. W.; Mitchell, E. G.; Casenove, D.; Mayers, C. 10.1101/566844 — paleontology — Posted on 2019-03-04 3017 Rapid, precise, and reliable phenotyping of delay discounting using Bayesian adaptive design optimization Ahn, W.-Y.; Gu, H.; Shen, Y.; Haines, N.; Teater, J. E.; Myung, J. I.; Pitt, M. A. 10.1101/567412 — neuroscience — Posted on 2019-03-04 3018 Deconvolving the contributions of cell-type heterogeneity on cortical gene expression Patrick, E.; Taga, M.; Ergun, A.; Ng, B.; Casazza, W.; Cimpean, M.; Yung, C.; Schneider, J. A.; Bennet, D. A.; Gaiteri, C.; De Jager, P. L.; Bradshaw, E. M.; Mostafavi, S. 10.1101/566307 — neuroscience — Posted on 2019-03-04 3019 The cellular response towards lanthanum is substrate specific and reveals a novel route for glycerol metabolism in Pseudomonas putida KT2440 Wehrmann, M.; Toussaint, M.; Pfannstiel, J.; Billard, P.; Klebensberger, J. 10.1101/567529 — microbiology — Posted on 2019-03-04 3020 The Paf1 complex broadly impacts the transcriptome of Saccharomyces cerevisiae Ellison, M. A.; Lederer, A. R.; Warner, M. H.; Mavrich, T.; Raupach, E. A.; Heisler, L. E.; Nislow, C.; Lee, M. T.; Arndt, K. M. 10.1101/567495 — genomics — Posted on 2019-03-04 3021 Systems biology of cold adaptation in the polyextremophilic red alga Galdieria sulphuraria Rossoni, A. W.; Weber, A. P. M. 10.1101/565861 — evolutionary biology — Posted on 2019-03-04 3022 A Novel and Efficient Approach for Screening Cancer Cell Specific Monoclonal Antibodies pei, X.-H. 10.1101/566398 — cancer biology — Posted on 2019-03-04 3023 Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase Pollock, K.; Liu, M.; Zaleska, M.; Pfuhl, M.; Collins, I.; Guettler, S. 10.1101/567446 — biophysics — Posted on 2019-03-04 3024 Uncovering hypergraphs of cell-cell interaction from single cell RNA-sequencing data Tsuyuzaki, K.; Ishii, M.; Nikaido, I. 10.1101/566182 — bioinformatics — Posted on 2019-03-04 3025 Optogenetic control of cell morphogenesis on protein micropatterns Zieske, K.; Mullins, R. D. 10.1101/563353 — bioengineering — Posted on 2019-03-04 3026 Characterizing the epigenetic landscape of cellular populations from bulk and single-cell ATAC-seq information. Gabitto, M. I.; Rasmussen, A.; Wapinski, O.; Allaway, K.; Carriero, N.; Fishell, G. J.; Bonneau, R. 10.1101/567669 — bioinformatics — Posted on 2019-03-04 3027 Functional RNA Structures in the 3’UTR of Tick-Borne, Insect-Specific and No-Known-Vector Flaviviruses Ochsenreiter, R.; Hofacker, I. L.; Wolfinger, M. T. 10.1101/565580 — bioinformatics — Posted on 2019-03-04 3028 12h-clock control of central dogma information flow by XBP1s Pan, Y.; Ballance, H.; Schnytzer, Y.; Chen, X.; Levy, O.; Coarfa, C.; Zhu, B. 10.1101/559039 — systems biology — Posted on 2019-03-04 3029 Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential PTP-1B Inhibitors Varshney, K.; Gupta, A. K.; Rawat, A.; Srivastava, R.; Mishra, A.; Saxena, M.; Srivastava, A. K.; Jain, S.; Saxena, A. K. 10.1101/472670 — pharmacology and toxicology — Posted on 2019-03-04 3030 Linear cortico-cortical mapping as a fundamental motif of brain connectivity organization O'Rawe, J. F.; Leung, H.-C. 10.1101/549345 — neuroscience — Posted on 2019-03-04 3031 Oxidative stress, telomere length, and frailty in an old age population Martinez-Ezquerro, J. D.; Rodriguez-Castaneda, A.; Ortiz-Ramirez, M.; Sanchez-Garcia, S.; Rosas-Vargas, H.; Sanchez-Arenas, R.; Garcia-delaTorre, P. 10.1101/414680 — molecular biology — Posted on 2019-03-04 3032 Intra- and interpatient evolution of enterovirus D68 analyzed by whole-genome deep sequencing Dyrdak, R.; Mastafa, M.; Hodcroft, E.; Neher, R.; Albert, J. 10.1101/420836 — microbiology — Posted on 2019-03-04 3033 Enteropathogen antibody dynamics and force of infection among children in low-resource settings Arnold, B. F.; Martin, D. L.; Juma, J.; Mkocha, H.; Ochieng, J. B.; Cooley, G. M.; Omore, R.; Goodhew, E. B.; Morris, J. F.; Costantini, V.; Vinje, J.; Lammie, P. J.; Priest, J. W. 10.1101/522920 — epidemiology — Posted on 2019-03-04 3034 Carnivore endozoochory of a dry-fruited tree can benefit quarry passive restoration Salgueiro, V.; Silva, C.; Eufrazio, S.; Salgueiro, P. A.; Vaz, P. G. 10.1101/561142 — ecology — Posted on 2019-03-04 3035 Optical flow analysis reveals that Kinesin-mediated advection impacts on the orientation of microtubules Drechsler, M.; Lang, L. F.; Dirks, H.; Burger, M.; Schoenlieb, C.-B.; Palacios, I. M. 10.1101/556043 — cell biology — Posted on 2019-03-04 3036 Beware the Jaccard: the choice of metric is important and non-trivial in genomic colocalisation analysis. Salvatore, S.; Rand, K. D.; Grytten, I.; Ferkingstad, E.; Domanska, D. E.; Holden, L.; Gheorghe, M.; Mathelier, A.; Glad, I.; Sandve, G. K. 10.1101/479253 — bioinformatics — Posted on 2019-03-04 3037 CRUMBLER: A tool for the Prediction of Ancestry in Cattle Crum, T. E.; Schnabel, R. D.; Decker, J. E.; Regitano, L. C.; Taylor, J. F. 10.1101/396341 — genomics — Posted on 2019-03-04 3038 Global expansion and redistribution of Aedes-borne virus transmission risk with climate change Ryan, S. J.; Carlson, C. J.; Mordecai, E. A.; Johnson, L. R. 10.1101/172221 — epidemiology — Posted on 2019-03-04 3039 Geography, not food availability, reflects compositional differences in the bacterial communities associated with larval sea urchins Carrier, T.; Dupont, S.; Reitzel, A. 10.1101/394486 — ecology — Posted on 2019-03-04 3040 An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation Tesi, A.; De Pretis, S.; Furlan, M.; Filipuzzi, M.; Morelli, M. J.; Andronache, A.; Doni, M.; Verrecchia, A.; Pelizzola, M.; Amati, B.; Sabo, A. 10.1101/561464 — cancer biology — Posted on 2019-03-04 3041 A comparative anatomy of protein crystals: lessons from the automatic processing of 56,000 samples Svensson, O.; Gilski, M.; Nurizzo, D.; Bowler, M. W. 10.1101/558023 — biophysics — Posted on 2019-03-04 3042 Tailoring 3D cell culture templates with common hydrogels. Pasturel, A.; Strale, P.-O.; Studer, V. 10.1101/370882 — bioengineering — Posted on 2019-03-04 3043 Human cortical organoids expose a differential function of GSK3 on direct and indirect neurogenesis Lopez Tobon, A.; Villa, C. E.; Cheroni, C.; Trattaro, S.; Caporale, N.; Conforti, P.; Iennaco, R.; Lachgar, M.; Rigoli, M. T.; Marco de la Cruz, B.; Lo Riso, P.; Tenderini, E.; Troglio, F.; de Simone, M.; Liste, I.; Piccolo, S.; Macino, G.; Pagani, M.; Cattaneo, E.; Testa, G. 10.1101/484741 — developmental biology — Posted on 2019-03-04 3044 Modeling motor neuron resilience in ALS using stem cells Allodi, I.; Nijssen, J.; Aguila Benitez, J. C.; Schweingruber, C.; Fuchs, A.; Bonvicini, G.; Cao, M.; Kiehn, O.; Hedlund, E. 10.1101/399659 — neuroscience — Posted on 2019-03-04 3045 Expanding Parkinson’s disease genetics: novel risk loci, genomic context, causal insights and heritable risk Nalls, M. A.; Blauwendraat, C.; Vallerga, C. L.; Heilbron, K.; Bandres-Ciga, S.; Chang, D.; Tan, M.; Kia, D. A.; Noyce, A. J.; Xue, A.; Bras, J.; Young, E.; von Coelln, R.; Simon-Sanchez, J.; Schulte, C.; Sharma, M.; Krohn, L.; Pihlstrom, L.; Siitonen, A.; Iwaki, H.; Leonard, H.; Faghri, F.; Gibbs, J. R.; Hernandez, D. G.; Scholz, S. W.; Botia, J. A.; Martinez, M.; Corvol, J.-C.; Lesage, S.; Jankovic, J.; Shulman, L. M.; The 23andMe Research Team, ; System Genomics of Parkinson's Disease (SGPD) Cons, ; Sutherland, M.; Tienari, P.; Majamaa, K.; Toft, M.; Brice, A.; Yang, J.; Gan-Orr, Z.; Gas 10.1101/388165 — genetics — Posted on 2019-03-04 3046 High satellite repeat turnover in great apes studied with short- and long-read technologies Cechova, M.; Harris, R. S.; Tomaszkiewicz, M.; Arbeithuber, B.; Chiaromonte, F.; Makova, K. D. 10.1101/470054 — evolutionary biology — Posted on 2019-03-04 3047 Neural circuits mediating visual stabilization during active motion in zebrafish Sun, S.; Zuo, Z.; Ma, M. M.; Qian, C.; Chen, L.; Zhou, W.; Drasbek, K. R.; Zuxiang, L. 10.1101/566760 — neuroscience — Posted on 2019-03-04 3048 A distributed neural code in the dentate gyrus and CA1 Stefanini, F.; Kheirbek, M. A.; Kushnir, L.; Jimenez, J. C.; Jennings, J. H.; Stuber, G. D.; Hen, R.; Fusi, S. 10.1101/292953 — neuroscience — Posted on 2019-03-04 3049 Modulation of coordinated activity across cortical layers by plasticity of inhibitory synapses onto layer 5 pyramidal neurons Lourenco, J.; De Stasi, A. M.; Deleuze, C.; Bigot, M.; Pazienti, A.; Aguirre, A.; Giugliano, M.; Ostojic, S.; Bacci, A. 10.1101/567065 — neuroscience — Posted on 2019-03-04 3050 Simulation of calcium signaling in fine astrocytic processes: effect of spatial properties on spontaneous activity Denizot, A.; Arizono, M.; Nägerl, V.; Soula, H.; Berry, H. 10.1101/567388 — neuroscience — Posted on 2019-03-04 3051 Nanopore sequencing of full-length circRNAs in human and mouse brains reveals circRNA-specific exon usage and intron retention Rahimi, K.; Veno, M. T.; Dupont, D. M.; Kjems, J. 10.1101/567164 — genetics — Posted on 2019-03-04 3052 Constraint-based analysis for causal discovery in population-based biobanks Amar, D.; Ashley, E.; Rivas, M. 10.1101/566133 — genetics — Posted on 2019-03-04 3053 Genetic divergence and phenotypic plasticity contribute to variation in cuticular hydrocarbons in the seaweed fly C. frigida Berdan, E. L.; Enge, S.; Nylund, G.; Wellenreuther, M.; Martens, G. A.; Pavia, H. 10.1101/303206 — evolutionary biology — Posted on 2019-03-04 3054 Ex vivo expansion of skeletal muscle stem cells with a novel small compound inhibitor of eIF2α dephosphorylation Lean, G.; Halloran, M.; Mariscal, O.; Jamet, S.; Lumb, J.-P.; Crist, C. 10.1101/567461 — cell biology — Posted on 2019-03-04 3055 Two pathways of p27Kip1 degradation are required for murine lymphoma driven by Myc and EBV latent membrane protein 2A Longnecker, R.; Ikeda, M.; Sora, R. P. 10.1101/564559 — microbiology — Posted on 2019-03-04 3056 Modelling microbiome recovery after antibiotics using a stability landscape framework Shaw, L. P.; Bassam, H.; Barnes, C. P.; Walker, A. S.; Klein, N.; Balloux, F. 10.1101/222398 — microbiology — Posted on 2019-03-04 3057 UniProt Genomic Mapping for Deciphering Functional Effects of Missense Variants McGarvey, P.; Nightingale, A.; Luo, J.; Huang, H.; Martin, M.-J.; Wu, C.; UniProt Consortium, 10.1101/192914 — genomics — Posted on 2019-03-04 3058 Chronic Intermittent Ethanol Exposure Differentially Alters Microglial Morphology in the Prelimbic Cortex and Nucleus Accumbens Core Siemsen, B.; Landin, J.; McFaddin, J.; Hooker, K.; Chandler, L. J.; Scofield, M. D. 10.1101/566034 — neuroscience — Posted on 2019-03-04 3059 Functional arrays of human pluripotent stem cell-derived cardiac microtissues Zandstra, P.; Thavandiran, N.; Hale, C.; Blit, P.; Sandberg, M. L.; McElvain, M. E.; Gagliardi, M.; Sun, B.; Witty, A.; Graham, G.; McIntosh, M.; Bakooshli, M. A.; Le, H.; Ostblom, J.; McEwen, S.; Chau, E.; Prowse, A.; Fernandes, I.; Gilbert, P. M.; Keller, G.; Tagari, P.; Xu, H.; Radisic, M. 10.1101/566059 — bioengineering — Posted on 2019-03-04 3060 Antigen structure affects cellular routing through DC-SIGN Jarvis, C.; Zwick, D. B.; Grim, J. C.; Prost, L. R.; Alam, M. M.; Gardiner, J.; Park, S.; Zimdars, L. L.; Sherer, N. M.; Kiessling, L. 10.1101/566141 — immunology — Posted on 2019-03-04 3061 Complex polymorphic genetic architecture underlies trans-regulatory variation among strains of Saccharomyces cerevisiae Metzger, B. P. H.; Wittkopp, P. J. 10.1101/566653 — evolutionary biology — Posted on 2019-03-04 3062 The Personal Genome Project-UK: an open access resource of human multi-omics data Chervova, O.; Conde, L.; Guerra-Assuncao, J. A.; Moghul, I.; Webster, A. P.; Berner, A.; Larose Cadieux, E.; Tian, Y.; Voloshin, V.; Hamoudi, R. A.; Herrero, J.; Beck, S. 10.1101/566711 — bioinformatics — Posted on 2019-03-04 3063 Injectable nanoclay gels for angiogenesis Page, D. J.; Clarkin, C. E.; Mani, R.; Khan, N. A.; Dawson, J. I.; Evans, N. D. 10.1101/566943 — bioengineering — Posted on 2019-03-04 3064 Quantifying Molecular Bias in DNA Data Storage Chen, Y.-J.; Takahashi, C. N.; Organick, L.; Stewart, K.; Ang, S. D.; Weiss, P.; Peck, B.; Seelig, G.; Ceze, L.; Strauss, K. 10.1101/566554 — synthetic biology — Posted on 2019-03-04 3065 GAPIN: Grouped and Aligned Protein Interface Networks Araujo, B. M.; Coelho, A. L.; Silveira, S. d. A.; Romanelli, J. P. R.; Minardi, R. C. d. M.; da Silveira, C. H. 10.1101/520833 — bioinformatics — Posted on 2019-03-04 3066 EpiAlign: an alignment-based bioinformatic tool for comparing chromatin state sequences Zhang, H.; Ge, X.; Li, W. V.; Xie, L.; Kwon, S. B.; Li, J. J. 10.1101/566299 — bioinformatics — Posted on 2019-03-04 3067 Na/K-ATPase Activity and Ketone Body Metabolism in Long-term Diabetic Rats Buxbaum, E. 10.1101/567180 — biochemistry — Posted on 2019-03-04 3068 Dynamics and Internal Control of Body Temperature in Response to Infectious Agents and other Causal Factors Schaper, C. 10.1101/566679 — physiology — Posted on 2019-03-04 3069 Insights into an alternative pathway for glycerol metabolism in a glycerol kinase deficient Pseudomonas putida KT2440 Walsh, M.; Casey, W.; Kenny, S. T.; Narancic, T.; Blank, L. M.; Wierckx, N.; Ballerstedt, H.; O Connor, K. E. 10.1101/567230 — microbiology — Posted on 2019-03-04 3070 The impact of DNA polymerase and number of rounds of amplification in PCR on 16S rRNA gene sequence data Sze, M. A.; Schloss, P. D. 10.1101/565598 — microbiology — Posted on 2019-03-04 3071 Chromatin arranges in filaments of blobs with nanoscale functional zonation Miron, E.; Oldenkamp, R.; Pinto, D. M.; Brown, J. M.; Carvalho Faria, A. R.; Shaban, H. A.; Rhodes, J. D.; Innocent, C.; de Ornellas, S.; Buckle, V.; Schermelleh, L. 10.1101/566638 — genomics — Posted on 2019-03-04 3072 Single particle trajectory statistic to reconstruct chromatin organization and dynamics Shukron, O.; Seeber, A.; Amitai, A.; Holcman, D. 10.1101/559369 — genomics — Posted on 2019-03-04 3073 EML4-ALK V3 drives cell migration through NEK9 and NEK7 kinases in non-small-cell lung cancer O'Regan, L.; Barone, G.; Adib, R.; Woo, C. G.; Jeong, H. J.; Richardson, E.; Richards, M.; Muller, P.; Collis, S.; Fennell, D.; Choi, J.; Bayliss, R.; Fry, A. M. 10.1101/567305 — cancer biology — Posted on 2019-03-04 3074 TmDOTP : An NMR- based Thermometer for Magic Angle Spinning NMR Experiments Zhang, D.; Itin, B.; McDermott, A. 10.1101/566729 — biophysics — Posted on 2019-03-04 3075 Molecular characterization of CHAD domains as inorganic polyphosphate binding modules Lorenzo-Orts, L.; Hohmann, U.; Zhu, J.; Hothorn, M. 10.1101/567040 — biochemistry — Posted on 2019-03-04 3076 A high-fat high-sugar diet in adolescent rats impairs social memory and alters chemical markers characteristic of atypical neuroplasticity and GABAergic neurodevelopment in the medial prefrontal cortex Reichelt, A. C.; Gibson, G. D.; Abbott, K. N.; Hare, D. J. 10.1101/566026 — neuroscience — Posted on 2019-03-04 3077 Multiple elements of addiction vulnerability are independently heritable in rats Eid, M.; Pullmann, D.; Li, H.; Jhou, T. 10.1101/566018 — neuroscience — Posted on 2019-03-04 3078 Threshold Electric Skin Sensitivity Fluctuations in Pregnancy, Labor and Puerperium. Rossmann, C. B. C.; Von Taaffe, C. T. 10.1101/565960 — neuroscience — Posted on 2019-03-04 3079 Norepinephrine controls the gain of the inhibitory circuit in the cerebellar input layer Lanore, F.; Rothman, J.; Coyle, D.; Silver, R. A. 10.1101/567172 — neuroscience — Posted on 2019-03-04 3080 The processing of continuously received visual information Caplette, L.; Ince, R. A. A.; Jerbi, K.; Gosselin, F. 10.1101/566042 — neuroscience — Posted on 2019-03-04 3081 Polymer brush bilayers under stationary shear motion at linear response regime: A theoretical approach Edwards, M. 10.1101/565796 — biophysics — Posted on 2019-03-04 3082 A framework for predicting soft-fruit yields and phenology using embedded, networked microsensors, coupled weather models and machine-learning techniques Lee, M.; Monteiro, A.; Barclay, A.; Marcar, J.; Miteva-Neagu, M.; Parker, J. 10.1101/565010 — plant biology — Posted on 2019-03-04 3083 Small RNA expression pattern in multiply inbred lines and their hybrids of maize embryo Liu, Y.-X. 10.1101/565911 — plant biology — Posted on 2019-03-04 3084 Mechanical stress initiates and sustains the morphogenesis of wavy leaf epidermal cells Bidhendi, A. J.; Altartouri, B.; Gosselin, F.; Geitmann, A. 10.1101/563403 — plant biology — Posted on 2019-03-04 3085 On Pectin Methyl-esterification: Implications for In vitro and In vivo Viscoelasticity Kaplan, J. L.; Torode, T. A.; Bou Daher, F.; Braybrook, S. A. 10.1101/565614 — plant biology — Posted on 2019-03-04 3086 Cryopreservation of Rosa hybrida cv. Helmut Schmidt by PVS2 vitrification method using in vitro fragmented explants (IFEs) Subramaniam, S.; Mubbarakh, S. A.; Udain, J.; James, J. J.; Zakaria, R. 10.1101/567255 — plant biology — Posted on 2019-03-04 3087 PCH1 regulates light, temperature, and circadian signaling as a structural component of phytochrome B-photobodies in Arabidopsis Huang, H.; McLoughlin, K.; Sorkin, M.; Burgie, E. S.; Bindbeutel, R.; Vierstra, R.; Nusinow, D. 10.1101/566687 — plant biology — Posted on 2019-03-04 3088 Value-driven attentional capture enhances distractor representations in early visual cortex Itthipuripat, S.; Vo, V. A.; Sprague, T. C.; Serences, J. 10.1101/567354 — neuroscience — Posted on 2019-03-04 3089 B-1 cell-mediated modulation of M1-macrophage profile can ameliorate microbicidal functions and disrupt the evasion mechanisms of Encephalitozoon cuniculi Pereira, A.; Alvares-Saraiva, A. M.; Konno, F. T. d. C.; Spadacci-Morena, D. D.; Perez, E. C.; Mariano, M.; Lallo, M. A. 10.1101/567404 — microbiology — Posted on 2019-03-04 3090 Association of Functional Variants and Protein-to-Protein Physical Interactions of Human MutY homolog linked with Familial Adenomatous Polyposis and colorectal cancer Syndrome Abduljaleel, Z. 10.1101/552943 — genetics — Posted on 2019-03-04 3091 The AAA+ ATPase TorsinA polymerizes into hollow tubes with a helical periodicity of 8.5 subunits per turn Demircioglu, E.; Zheng, W.; McQuown, A. J.; Maier, N.; Watson, N.; Cheeseman, I. M.; Denic, V.; Egelman, E. H.; Schwartz, T. U. 10.1101/567099 — biochemistry — Posted on 2019-03-04 3092 Caffeine but not acetaminophen increases 4-km cycling time-trial performance Lima-Silva, A. E.; Tomazini, F.; Mariano, A. C. S.; Andrade-Souza, V. A.; Sebben, V. C.; de Maria, C. A. B.; Coelho, D. B.; Bertuzzi, R.; Silva-Cavalcante, M. D. 10.1101/567313 — physiology — Posted on 2019-03-04 3093 NOVEL ORGAN-SPECIFIC GENETIC FACTORS FOR QUANTITATIVE RESISTANCE TO LATE BLIGHT IN POTATO Juyo Rojas, D. K.; Soto Sedano, J. C.; Ballvora, A.; Leon, J.; Mosquera Vasquez, T. 10.1101/567289 — genetics — Posted on 2019-03-04 3094 Chronic alcohol abuse affects the clinical course and outcome ofcommunity-acquired bacterial meningitis Paciorek, M.; Bednarska, A.; Krogulec, D.; Makowiecki, M.; Kowalska, J. D.; Bursa, D.; Swiderska, A.; Puła, J.; Raczynska, J.; Skrzat-Klapaczynska, A.; Radkowski, M.; Laskus, T.; Horban, A. 10.1101/567347 — epidemiology — Posted on 2019-03-04 3095 Description and lessons learned from the 2014 Dengue outbreak in Dar es Salaam, Tanzania. Knowledge, attitudes and bite prevention practices among those with confirmed Dengue Msellemu, D.; Gavana, T.; Ngonyani, H.; Mlacha, Y. P.; Chaki, P.; Moore, S. J. 10.1101/567396 — epidemiology — Posted on 2019-03-04 3096 Molecular evolution guided functional analyses reveals Nucleobindin-1 as a canonical E-box binding protein promoting Epithelial-to-Mesenchymal transition (EMT) Sinha, S.; Pattnaik, S.; Aradhyam, G. K. 10.1101/566836 — cell biology — Posted on 2019-03-04 3097 Single-Cell RNA Sequencing Reveals Regulatory Mechanism for Trophoblast Cell-Fate Divergence in Human Peri-Implantation Embryo Lv, B.; An, Q.; Zeng, Q.; Lu, P.; Zhu, X.; Ji, Y.; Fan, G.; Xue, Z. 10.1101/567362 — cell biology — Posted on 2019-03-04 3098 Exploiting evolutionary herding to control drug resistance in cancer Acar, A.; Nichol, D.; Fernandez, J.; Cresswell, G. D.; Barozzi, I.; Hong, S. P.; Spiteri, I.; Stubbs, M.; Burke, R.; Stewart, A.; Vlachogiannis, G.; Maley, C. C.; Magnani, L.; Valeri, N.; Banerji, U.; Sottoriva, A. 10.1101/566950 — cancer biology — Posted on 2019-03-04 3099 An interplay between reaction-diffusion and cell-matrix adhesion regulates multiscale invasion in early breast carcinomatosis Pally, D.; Pramanik, D.; Bhat, R. 10.1101/566612 — cancer biology — Posted on 2019-03-04 3100 Mouth Function Determines The Shape Oscillation Pattern In Regenerating Hydra Tissue Spheres Wang, R.; Goel, T.; Khazoyan, K.; Sabry, Z.; Quan, H. J.; Diamond, P. H.; Collins, E.-M. S. 10.1101/565465 — biophysics — Posted on 2019-03-04 3101 Allosteric studies of an open pH gate KcsA mutant in its activated and inactivated states Sun, Z.; Xu, Y.; Zhang, D.; McDermott, A. E. 10.1101/567024 — biophysics — Posted on 2019-03-04 3102 Sex differences in gene expression and proliferation are dependent on the epigenetic modifier HP1γ Law, P. P.; Chan, P.-K.; McEwen, K.; Zhi, H.; Liang, B.; Chie, N.; Asano, M.; Tan-Un, K.-C.; Chan, G. C.-F.; Festenstein, R. 10.1101/563940 — developmental biology — Posted on 2019-03-04 3103 Distinct RhoGEFs activate apical and junctional actomyosin contractility under control of G proteins during epithelial morphogenesis Garcia De Las Bayonas, A.; Philippe, J.-M.; Lellouch, A.; Lecuit, T. 10.1101/566919 — developmental biology — Posted on 2019-03-04 3104 Untangling the Evolutionary History of European Bison (Bison bonasus) van Loenen, A. L.; Hofman-Kaminska, E.; Mitchell, K. J.; Llamas, B.; Bocherens, H.; Soubrier, J.; Heiniger, H.; Pacher, M.; Makowiecki, D.; Piliciauskiene, G.; Drucker, D.; Kowalczyk, R.; Cooper, A. 10.1101/467951 — evolutionary biology — Posted on 2019-03-04 3105 Structure-specific regulation of nutrient absorption, metabolism and transfer in arbuscular mycorrhizal fungi Kameoka, H.; Maeda, T.; Okuma, N.; Kawaguchi, M. 10.1101/491811 — plant biology — Posted on 2019-03-03 3106 Contribution of Apical and Basal Dendrites of L2/3 Pyramidal Neurons to Orientation Encoding in Mouse V1 Park, J.; Papoutsi, A.; Ash, R. T.; Marin, M. A.; Poirazi, P.; Smirnakis, S. M. 10.1101/566588 — neuroscience — Posted on 2019-03-03 3107 Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling. Liang, Q.; Dharmat, R.; Owen, L.; Shakoor, A.; Li, Y.; Kim, S.; Vitale, A.; Kim, I.; Morgan, D.; Wu, N.; DeAngelis, M.; Chen, R. 10.1101/468207 — genomics — Posted on 2019-03-03 3108 The Genomic Landscape of Centromeres in Cancers Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R. 10.1101/505800 — genomics — Posted on 2019-03-03 3109 Massive computational acceleration by using neural networks to emulate mechanism-based biological models Wang, S.; Kai, F.; Luo, N.; Cao, Y.; Wu, F.; Zhang, C.; Heller, K. A.; You, L. 10.1101/559559 — systems biology — Posted on 2019-03-03 3110 Optical imaging of single protein size, charge, mobility, binding and conformational change Ma, G.; Zhu, H.; Wan, Z.; Yang, Y.; Wang, S.; Tao, N. 10.1101/505404 — biophysics — Posted on 2019-03-03 3111 Galanin neurons in the hypothalamus link sleep homeostasis, body temperature and actions of the alpha2 adrenergic agonist dexmedetomidine Ma, Y.; Miracca, G.; Yu, X.; Harding, E. C.; Miao, A.; Yustos, R.; Vyssotski, A. L.; Franks, N. P.; Wisden, W. 10.1101/565747 — neuroscience — Posted on 2019-03-03 3112 Genomic decoding of neuronal depolarization by stimulus-specific NPAS4 heterodimers Brigidi, G. S.; Hayes, M. G. B.; Hartzell, A. L.; Texari, L.; Lin, P.-A.; Bartlett, A.; Ecker, J. R.; Benner, C.; Heinz, S.; Bloodgood, B. L. 10.1101/565721 — neuroscience — Posted on 2019-03-03 3113 Structured Inhibitory Activity Dynamics During Learning Arriaga, M.; Han, E. B. 10.1101/566257 — neuroscience — Posted on 2019-03-03 3114 How helpful are the protein-protein interaction databases and which ones? Bajpai, A. K.; Davuluri, S.; Tiwary, K.; Narayanan, S.; Oguru, S.; Basavaraju, K.; Dayalan, D.; Thirumurugan, K.; Acharya, K. K. 10.1101/566372 — bioinformatics — Posted on 2019-03-03 3115 Social status in mouse social hierarchies is associated with variation in oxytocin and vasopressin 1a receptor densities Lee, W.; Hiura, L.; Yang, E.; Broekman, K. A.; Ophir, A. G.; Curley, J. 10.1101/566067 — neuroscience — Posted on 2019-03-03 3116 Differential in vivo biodistribution of 131I-labeled exosomes from diverse cellular origins and its implication in the theranostic application. Rashid, M. H.; Borin, T. F.; Ara, R.; Angara, K.; Cai, J.; Achyut, B.; Liu, Y.; Arbab, A. S. 10.1101/566323 — cancer biology — Posted on 2019-03-03 3117 Rho-dependent control of the Citron kinase, Sticky, drives midbody ring maturation. El-amine, N.; Carim, S. C.; Wernike, D.; Hickson, G. R. 10.1101/566463 — cell biology — Posted on 2019-03-03 3118 Programmable Modulation for Extracellular Vesicles Wang, Y.; Melvin, R.; Bemis, L. T.; Worrell, G. A.; Wang, H.-L. 10.1101/566448 — neuroscience — Posted on 2019-03-03 3119 The Marginal Cells of the Caenorhabditis elegans Pharynx Scavenge Cholesterol and Other Hydrophobic Small Molecules Kamal, M.; Moshiri, H.; Magomedova, L.; Han, D.; Nguyen, K. C.; Yeo, M.; Knox, J.; Bagg, R.; Won, A. M.; Szlapa, K.; Yip, C.; Cummins, C. L.; Hall, D. H.; Roy, P. J. 10.1101/565473 — developmental biology — Posted on 2019-03-03 3120 Systematic identification of regulators of antibody-drug conjugate toxicity using CRISPR-Cas9 screens Tsui, C. K.; Barfield, R. M.; Fischer, C. R.; Morgens, D. W.; Li, A.; Smith, B. A. H.; Bertozzi, C. R.; Rabuka, D.; Bassik, M. C. 10.1101/557454 — cancer biology — Posted on 2019-03-03 3121 Radiation resistant cancer cells enhance the survival and resistance of sensitive cells in prostate spheroids Kannan, P.; Paczkowski, M.; Miar, A.; Owen, J.; Kretzschmar, W. W.; Lucotti, S.; Kaeppler, J.; Chen, J.; Markelc, B.; Kunz-Schughart, L. A.; Harris, A. L.; Partridge, M.; Byrne, H. 10.1101/564724 — cancer biology — Posted on 2019-03-03 3122 A Complex Interplay of Anionic Phospholipid Binding Regulates 3-Phosphoinositide-Dependent-Kinase-1 Homodimer Activation De Las Heras, G.; Calleja, V.; Bailly, R.; Dessolin, J.; Requejo-Isidro, J.; Larijani, B. 10.1101/566430 — biophysics — Posted on 2019-03-03 3123 A Framework for Collective Behavior in Plant Inspired Growth-Driven Systems, Based on Kinematics of Allotropism Bastien, R.; Porat, A.; Meroz, Y. 10.1101/566364 — biophysics — Posted on 2019-03-03 3124 Influenza A matrix protein M1 is sufficient to induce lipid membrane deformation Dahmani, I.; Ludwig, K.; Chiantia, S. 10.1101/565952 — biophysics — Posted on 2019-03-03 3125 Machine learning-guided channelrhodopsin engineering enables minimally-invasive optogenetics Bedbrook, C. N.; Yang, K. K.; Robinson, J. E.; Gradinaru, V.; Arnold, F. H. 10.1101/565606 — bioengineering — Posted on 2019-03-03 3126 Post-transcriptional regulation of Nrf2-mRNA by the mRNA-binding proteins HuR and AUF1 Poganik, J. R.; Long, M. J.; Disare, M. T.; Liu, X.; Chang, S.-H.; Hla, T.; Aye, Y. 10.1101/565937 — biochemistry — Posted on 2019-03-03 3127 Vimentin protects the structural integrity of the nucleus and suppresses nuclear damage caused by large deformations Patteson, A. E.; Vahabikashi, A.; Pogoda, K.; Adam, S. A.; Goldman, A.; Goldman, R.; Janmey, P. 10.1101/566174 — cell biology — Posted on 2019-03-03 3128 RanBP2/Nup358 enhances RNAi activity by sumoylating and stabilizing Argonaute 1 Shen, Q.; Mathew, T.; Mahadevan, K.; Wang, Y. E.; Wu, J. Z.; Palazzo, A. F. 10.1101/555896 — molecular biology — Posted on 2019-03-03 3129 Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations Bueren-Calabuig, J. A.; Bage, M.; Cowling, V. H.; Pisliakov, A. V. 10.1101/558502 — biophysics — Posted on 2019-03-03 3130 Sensitive determination of proteolytic proteoforms in limited microscale proteome samples Weng, S. S. H.; Demir, F.; Ergin, E. K.; Dirnberger, S.; Uzozie, A.; Tuscher, D.; Nierves, L.; Tsui, J.; Huesgen, P. F.; Lange, P. F. 10.1101/566109 — biochemistry — Posted on 2019-03-03 3131 MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis qiu, h.; Chen, F.; Chen, M. 10.1101/566224 — cancer biology — Posted on 2019-03-03 3132 Antitumor Activities and Cellular Changes Induced by TrkB Inhibition in Medulloblastoma Thomaz, A.; Pinheiro, K. d. V.; Souza, B. K.; Gregianin, L.; Brunetto, A. L.; Brunetto, A. T.; de Farias, C. B.; Jaeger, M. d. C.; Ramaswamy, V.; Nor, C.; Taylor, M. D.; Roesler, R. 10.1101/566000 — cancer biology — Posted on 2019-03-03 3133 Computational Design of Myristoylated Cell Penetrating Peptides Targeting Oncogenic K-Ras.G12D at the Effector Binding Membrane Interface Li, Z.; Buck, M. 10.1101/565945 — biophysics — Posted on 2019-03-03 3134 Digital removal of autofluorescence from microscopy images Baharlou, H.; Canete, N. P.; Bertram, K. M.; Sandgren, K. J.; Cunningham, A. L.; Harman, A. N.; Patrick, E. 10.1101/566315 — bioinformatics — Posted on 2019-03-03 3135 C-type lectins CTL4 and CTLMA2: conserved heterodimeric structure and glycan specificity in Anopheles mosquitoes Bishnoi, R.; Contet, A.; Day, C. J.; Hou, D. C.-F.; Profitt, L. A.; Singla, D.; Sousa, G. L.; Jennings, M. P.; Povelones, M.; Valentine, A. M.; Baxter, R. H. G. 10.1101/565705 — biochemistry — Posted on 2019-03-03 3136 Adrenergic signaling in muscularis macrophages limits neuronal death following enteric infection Matheis, F.; Muller, P. A.; Graves, C. L.; Gabanyi, I.; Kerner, Z. J.; Costa-Borges, D.; Mucida, D. 10.1101/556340 — immunology — Posted on 2019-03-03 3137 Epithelial retinoic acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity Gattu, S.; Bang, Y.-J.; Pendse, M.; Dende, C.; Chara, A. L.; Harris, T. A.; Wang, Y.; Ruhn, K. A.; Kuang, Z.; Sockanathan, S.; Hooper, L. V. 10.1101/563908 — immunology — Posted on 2019-03-03 3138 Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre PBR28 HRRT PET study Tuisku, J.; Plaven-Sigray, P.; Gaiser, E. C.; Airas, L.; Al-Abdulrasul, H.; Brück, A.; Carson, R. E.; Chen, M.-K.; Cosgrove, K. P.; Ekblad, L.; Esterlis, I.; Farde, L.; Forsberg, A.; Halldin, C.; Helin, S.; Kosek, E.; Lekander, M.; Lindgren, N.; Marjamäki, P.; Rissanen, E.; Sucksdorff, M.; Varrone, A.; HRRT [11C]PBR28 study group, ; Rinne, J.; Matuskey, D.; Cervenka, S. 10.1101/564831 — immunology — Posted on 2019-03-03 3139 Beyond Core Object Recognition: Recurrent processes account for object recognition under occlusion Rajaei, K.; Mohsenzadeh, Y.; Ebrahimpour, R.; Khaligh-Razavi, S.-M. 10.1101/302034 — neuroscience — Posted on 2019-03-03 3140 Wnt activator FOXB2 drives prostate cancer neuroendocrine differentiation Moparthi, L.; Pizzolato, G.; Koch, S. 10.1101/564625 — cancer biology — Posted on 2019-03-03 3141 Natural variation in the roles of C. elegans autophagy components during microsporidia infection Balla, K.; Lazetic, V.; Troemel, E. 10.1101/418749 — immunology — Posted on 2019-03-03 3142 Flv1-4 proteins function in versatile combinations in O2 photoreduction in cyanobacteria Santana Sanchez, A. I.; Solymosi, D.; Mustila, H.; Bersanini, L.; Aro, E.-M.; Allahverdiyeva, Y. 10.1101/561456 — biochemistry — Posted on 2019-03-03 3143 Tailoring 3D cell culture templates with common hydrogels. Pasturel, A.; Strale, P.-O.; Studer, V. 10.1101/370882 — bioengineering — Posted on 2019-03-03 3144 Bridging the gap between single-cell migration and collective dynamics Thüroff, F.; Goychuk, A.; Reiter, M.; Frey, E. 10.1101/548677 — biophysics — Posted on 2019-03-02 3145 Splice junction centric approach to identify translated noncanonical isoforms in the human proteome Lau, E.; Han, Y.; Lam, M. P. Y. 10.1101/372995 — systems biology — Posted on 2019-03-02 3146 A Monte Carlo method for in silico modeling and visualization of Waddington's epigenetic landscape with intermediate details Zhang, X.; Chong, K. H.; Zheng, J. 10.1101/310771 — systems biology — Posted on 2019-03-02 3147 Age-related kinematic performance must be considered during fast head- neck rotation target task in individuals aged from 8 to 85 years old Hage, R.; Dierick, F.; Roussel, N.; Pitance, L.; Detrembleur, C. 10.1101/519488 — physiology — Posted on 2019-03-02 3148 The influence of fluctuating population densities on evolutionary dynamics Pisa, H.; Hermisson, J.; Polechova, J. 10.1101/444273 — evolutionary biology — Posted on 2019-03-02 3149 A quantitative genetics approach to the evolution of phenotypic (co)variance under limited dispersal, with an application to socially synergistic traits Mullon, C.; Lehmann, L. 10.1101/393538 — evolutionary biology — Posted on 2019-03-02 3150 HDAC and MAPK/ERK Inhibitors Cooperate to Reduce Viability and Stemness Phenotype in Medulloblastoma Jaeger, M. d. C.; Ghisleni, E. C.; Cardoso, P. S.; Siniglaglia, M.; Falcon, T.; Brunetto, A. T.; Brunetto, A. L.; de Farias, C. B.; Taylor, M. D.; Nor, C.; Ramaswamy, V.; Roesler, R. 10.1101/521393 — cancer biology — Posted on 2019-03-02 3151 Global transcriptome analysis of the Myxococcus xanthus multicellular developmental program Munoz-Dorado, J.; Moraleda-Munoz, A.; Marcos-Torres, F. J.; Contreras-Moreno, F. J.; Martin-Cuadrado, A. B.; Schrader, J. M.; Higgs, P. I.; Perez, J. 10.1101/564641 — microbiology — Posted on 2019-03-02 3152 Analysis on epidemiological characteristics of 4 species natural-focal diseases in Shandong Province, China in 2009-2017: a descriptive analysis Chen, R.; Kou, Z.; Xu, L.; Cao, J.; Liu, Z.; Wen, X.; Wang, Z.; hongling, W. 10.1101/564971 — epidemiology — Posted on 2019-03-02 3153 Scans of the MYC mRNA reveal multiple stable secondary structures—including a 3′ UTR motif, conserved across vertebrates, that can affect gene expression. O'Leary, C.; Andrews, R.; Tompkins, V.; Chen, J.; Childs-Disney, J.; Disney, M.; Moss, W. N. 10.1101/564864 — bioinformatics — Posted on 2019-03-02 3154 Compositional Data Analysis is necessary for simulating and analyzing RNA-Seq data McGee, W. A.; Pimentel, H.; Pachter, L.; Wu, J. Y. 10.1101/564955 — bioinformatics — Posted on 2019-03-02 3155 Syndecan-1 facilitates breast cancer metastasis to the brain Sayyad, M. R.; Puchalapalli, M.; Vergara, N. G.; Mosticone Wangensteen, S.; Moore, M.; Mu, L.; Edwards, C.; Anderson, A.; Kall, S.; Sullivan, M.; Dozmorov, M.; Singh, J.; Idowu, M. O.; Koblinski, J. E. 10.1101/565648 — cancer biology — Posted on 2019-03-02 3156 Relating brain connectivity with persistent symptoms in pediatric concussion Iyer, K. K.; Barlow, K. M.; Brooks, B.; Ofoghi, Z.; Zalesky, A.; Cocchi, L. 10.1101/539825 — neuroscience — Posted on 2019-03-02 3157 Fingerprinting Adiposity and Metabolic Function in the Brains of Overweight and Obese Humans Farruggia, M. C.; van Kooten, M. J.; Burke, M. V.; Scheinost, D.; Constable, R. T.; Small, D. M. 10.1101/540997 — neuroscience — Posted on 2019-03-01 3158 Field application of an eDNA assay for the endangered white-clawed crayfish Austropotamobius pallipes Atkinson, S.; Carlsson, J. E. L.; Ball, B.; Kelly-Quinn, M.; Carlsson, J. 10.1101/562710 — genetics — Posted on 2019-03-01 3159 A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance Boyer, N. P.; McCormick, L. E.; Urbina, F. L.; Gupton, S. 10.1101/529222 — cell biology — Posted on 2019-03-01 3160 Conditional approach as cooperation in predator inspection: a role for serotonin? Pimentel, A. F. N.; Carvalho, T. d. S.; Lima, F.; Lima-Maximino, M. G.; Soares, M. C.; Maximino, C. 10.1101/436345 — animal behavior and cognition — Posted on 2019-03-01 3161 Measuring phenotypic heterogeneity in isogenic bacterial populations using flow cytometry and Raman spectroscopy Garcia-Timermans, C.; Rubbens, P.; Heyse, J.; Props, R.; Kerckhof, F.-M.; Skirtach, A.; Waegeman, W.; Boon, N. 10.1101/545681 — bioengineering — Posted on 2019-03-01 3162 A Novel Ensemble-Based Machine Learning Algorithm To Predict The Conversion From Mild Cognitive Impairment To Alzheimer's Disease Using Socio-demographic Characteristics, Clinical Information And Neuropsychological Measures Grassi, M.; Rouleaux, N.; Caldirola, D.; Loewenstein, D.; Schruers, K.; Perna, G.; Dumontier, M. 10.1101/564716 — neuroscience — Posted on 2019-03-01 3163 Low dimensional dynamics for working memory and time encoding Cueva, C. J.; Marcos, E.; Saez, A.; Genovesio, A.; Jazayeri, M.; Romo, R.; Salzman, C. D.; Shadlen, M. N.; Fusi, S. 10.1101/504936 — neuroscience — Posted on 2019-03-01 3164 Global biochemical and structural analysis of the type IV pilus from the Gram-positive bacterium Streptococcus sanguinis Berry, J.-L.; Gurung, I.; Anonsen, J. H.; Spielman, I.; Harper, E.; Hall, A. M. J.; Goosens, V. J.; Raynaud, C.; Koomey, M.; Biais, N.; Matthews, S.; Pelicic, V. 10.1101/459388 — microbiology — Posted on 2019-03-01 3165 Pan-Cancer and Single-Cell modelling of genomic alterations through gene expression Mercatelli, D.; Ray, F.; Giorgi, F. M. 10.1101/492561 — systems biology — Posted on 2019-03-01 3166 Association between development of early cortical activity on amplitude-integrated EEG and 5-years neurodevelopmental outcome in the preterm infant Feldmann, M.; Rousson, V.; Nguyen, T. D.; Bernet, V.; Hagmann, C.; Latal, B.; Natalucci, G. 10.1101/562488 — neuroscience — Posted on 2019-03-01 3167 A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution Packer, J. S.; Zhu, Q.; Huynh, C.; Sivaramakrishnan, P.; Preston, E.; Dueck, H.; Stefanik, D.; Tan, K.; Trapnell, C.; Kim, J.; Waterston, R. H.; Murray, J. I. 10.1101/565549 — genomics — Posted on 2019-03-01 3168 The alternative reality of plant mitochondrial DNA Kozik, A.; Rowan, B.; Lavelle, D.; Berke, L.; Schranz, M. E.; Michelmore, R. W.; Christensen, A. C. 10.1101/564278 — genomics — Posted on 2019-03-01 3169 Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin Auslander, N.; Heselmeyer-Haddad, K.; Patkar, S.; Hirsch, D.; Camps, J.; Brown, M.; Bronder, D.; Chen, W.-D.; Lokanga, R.; Wangsa, D.; Wangsa, D.; Hu, Y.; Lischka, A.; Braun, R.; Emons, G.; Ghadimi, B. M.; Gaedcke, J.; Grade, M.; Montagna, C.; Lazebnik, Y.; Difilippantonio, M. J.; Habermann, J. K.; Auer, G.; Ruppin, E.; ried, t. 10.1101/563858 — cancer biology — Posted on 2019-03-01 3170 Environmental plasticity and colonisation history in the Atlantic salmon microbiome: a translocation experiment Uren Webster, T.; Rodriguez Barreto, D.; Castaldo, G.; Taylor, J.; Gough, P.; Consuegra, S.; Garcia de Leaniz, C. 10.1101/564104 — microbiology — Posted on 2019-03-01 3171 Uncovering the role of admixture in disease and drug response: Association of hepatocyte gene expression and DNA methylation with African Ancestry in African Americans. Park, S. C.; De, T.; Xu, Y.; Zhoug, Y.; Gamazon, E.; Alarcon, C.; Perera, M. 10.1101/491225 — genomics — Posted on 2019-03-01 3172 Heterozygous missense RAD21 variant in a peripheral sclerocornea pedigree Zhang, B. N.; Chan, T. C. Y.; Tam, P. O. S.; Liu, Y.; Pang, C. P.; Jhanji, V.; Chen, L. J.; Chu, W. K. 10.1101/547547 — genetics — Posted on 2019-03-01 3173 Molecular evolution in small steps under prevailing negative selection - A nearly-universal rule of codon substitution Chen, Q.; Lan, A.; Shen, X.; Wu, C.-I. 10.1101/510735 — evolutionary biology — Posted on 2019-03-01 3174 The UCSC Xena Platform for cancer genomics data visualization and interpretation Goldman, M.; Craft, B.; Hastie, M.; Repecka, K.; Kamath, A.; McDade, F.; Rogers, D.; Brooks, A. N.; Zhu, J.; Haussler, D. 10.1101/326470 — cancer biology — Posted on 2019-03-01 3175 Patterns, Profiles, and Parsimony: dissecting transcriptional signatures from minimal single-cell RNA-seq output with SALSA Lozoya, O. A.; McClelland, K. S.; Papas, B.; Li, J.-L.; Yao, H. H.-C. 10.1101/551762 — bioinformatics — Posted on 2019-03-01 3176 Fundamental bounds on learning performance in neural circuits Raman, D. V.; O'Leary, T. 10.1101/508994 — neuroscience — Posted on 2019-03-01 3177 The Genomic Landscape of Centromeres in Cancers Saha, A.; Mourad, M.; Kaplan, M. H.; Chefetz, I.; Malek, S. N.; Buckanovich, R.; Markovitz, D. M.; Contreras-Galindo, R. 10.1101/505800 — genomics — Posted on 2019-03-01 3178 Genomic analysis reveals a functional role for myocardial trabeculae in adults Meyer, H. V.; Dawes, T. J.; Serrani, M.; Bai, W.; Tokarczuk, P.; Cai, J.; de Marvao, A.; Rueckert, D.; Matthews, P. M.; Costantino, M. L.; Birney, E.; Cook, S. A.; O'Regan, D. P. 10.1101/553651 — genomics — Posted on 2019-03-01 3179 Mapping drinking water and quality of life aspects in urban settings: a proof-of-concept study on the application of the urban exposome framework Andrianou, X. D.; van der Lek, C.; Charisiadis, P.; Ioannou, S.; Fotopoulou, K. N.; Papapanagiotou, Z.; Botsaris, G.; Beumer, C.; Makris, K. C. 10.1101/401927 — epidemiology — Posted on 2019-03-01 3180 Salicylate increases fitness cost associated with MarA-mediated antibiotic resistance Wang, T.; Kunze, C.; Dunlop, M. J. 10.1101/454983 — systems biology — Posted on 2019-03-01 3181 Binding specificities of human RNA binding proteins towards structured and linear RNA sequences Jolma, A.; Zhang, J.; Mondragon, E.; Kivioja, T.; Yin, Y.; Zhu, F.; Morris, Q.; Hughes, T. R.; Maher, L. J.; Taipale, J. 10.1101/317909 — genomics — Posted on 2019-03-01 3182 Theory of cytoskeletal reorganization during crosslinker-mediated mitotic spindle assembly Lamson, A.; Edelmaier, C.; Glaser, M. A.; Betterton, M. 10.1101/419135 — cell biology — Posted on 2019-03-01 3183 EECoG-Comp: An Open Source Platform for Concurrent EEG/ECoG Comparisons: applications to connectivity stuides Wang, Q.; Valdes-Hernandez, P. A.; Paz-Linares, D.; Bosch-Bayard, J.; Oosugi, N.; Komatsu, M.; Fujii, N.; Valdes-Sosa, P. A. 10.1101/350199 — bioinformatics — Posted on 2019-03-01 3184 Best Prediction of the Additive Genomic Variance in Random-Effects Models Schreck, N.; Piepho, H.-P.; Schlather, M. 10.1101/282343 — genomics — Posted on 2019-03-01 3185 A Stochastic Model for Cancer Metastasis: Branching Stochastic Process with Settlement Frei, C.; Hillen, T.; Rhodes, A. 10.1101/294157 — cancer biology — Posted on 2019-03-01 3186 Choice history biases subsequent evidence accumulation Urai, A. E.; de Gee, J. W.; Tsetsos, K.; Donner, T. H. 10.1101/251595 — neuroscience — Posted on 2019-03-01 3187 A state-dependent mean-field formalism to model different activity states in conductance based networks of spiking neurons Capone, C.; di Volo, M.; Romagnoni, A.; Mattia, M.; Destexhe, A. 10.1101/565127 — neuroscience — Posted on 2019-03-01 3188 Network resonance during slow-wave sleep facilitates memory consolidation through phase-coding Skilling, Q.; Clawson, B. C.; Eniwaye, B.; Shaver, J.; Ognjanovski, N.; Atan, S. J.; Zochowski, M. 10.1101/565242 — neuroscience — Posted on 2019-03-01 3189 Translation enhancement by a Dictyostelium gene sequence in Escherichia coli Kondo, T.; Yumura, S. 10.1101/564815 — microbiology — Posted on 2019-03-01 3190 Epithelial retinoid acid receptor β regulates serum amyloid A expression and vitamin A-dependent intestinal immunity Gattu, S.; Bang, Y.-J.; Pendse, M.; Dende, C.; Chara, A. L.; Harris, T. A.; Wang, Y.; Ruhn, K. A.; Kuang, Z.; Sockanathan, S.; Hooper, L. V. 10.1101/563908 — immunology — Posted on 2019-03-01 3191 Exon-mediated activation of transcription starts Fiszbein, A.; Krick, K. S.; Burge, C. B. 10.1101/565184 — genomics — Posted on 2019-03-01 3192 TGF-β family ligands exhibit distinct signaling dynamics that are driven by receptor localization Miller, D. S. J.; Schmierer, B.; Hill, C. S. 10.1101/565416 — cell biology — Posted on 2019-03-01 3193 A Mathematical Model for the Immune-Mediated Theory of Metastasis Rhodes, A.; Hillen, T. 10.1101/565531 — cancer biology — Posted on 2019-03-01 3194 Prediction of condition-specific regulatory maps in Arabidopsis using integrated genomic data Song, Q.; Lee, J.; Akter, S.; Grene, R.; Li, S. 10.1101/565119 — bioinformatics — Posted on 2019-03-01 3195 A stimuli-responsive, pentapeptide, nanofiber hydrogel for tissue engineering Tang, J. D.; Mura, C.; Lampe, K. J. 10.1101/565317 — bioengineering — Posted on 2019-03-01 3196 Molecular Phenotyping of Oxidative Stress in Diabetes Mellitus with Point-of-care NMR system Peng, W. K.; Chen, L.; Boehm, B. O.; Han, J.; Loh, T. P. 10.1101/565325 — bioengineering — Posted on 2019-03-01 3197 Temporal Metrics of Multisensory Processing Change in the Elderly Basharat, A.; Barnett-Cowan, M.; Mahoney, J. R. 10.1101/565507 — neuroscience — Posted on 2019-03-01 3198 Replay as wavefronts and theta sequences as bump oscillations in a grid cell attractor network Kang, L.; DeWeese, M. R. 10.1101/565440 — neuroscience — Posted on 2019-03-01 3199 Structural basis of the differential binding of engineered knottins 2.5F and 2.5D to integrins αVβ3 and α5β1 van Agthoven, J. F.; Shams, H.; Cochran, F. V.; Alonso, J. L.; Kintzing, J. R.; Grakami, K.; Xiong, J.-P.; Mofrad, M. R.; Cochran, J. R.; Arnaout, M. A. 10.1101/565358 — molecular biology — Posted on 2019-03-01 3200 Low-dose antibiotics can collapse gut bacterial populations via a gelation transition Schlomann, B. H.; Wiles, T. J.; Wall, E. S.; Guillemin, K.; Parthasarathy, R. 10.1101/565556 — microbiology — Posted on 2019-03-01 3201 Sphingomyelin is critical in organizing phosphoinositide dynamics during phagocytic uptake of Mycobacterium tuberculosis. Niekamp, P.; Guzman, G.; Leier, H.; Rashidfarrokhi, A.; Richina, V.; Holthuis, J.; Tafesse, F. G. 10.1101/565226 — microbiology — Posted on 2019-03-01 3202 Antibiotic resistome and microbial community structure during anaerobic co-digestion of food waste, paper and cardboard Kanger, K.; Guilford, N. G. H.; Lee, H. P.; Nesbo, C. L.; Truu, J.; Edwards, E. A. 10.1101/564823 — microbiology — Posted on 2019-03-01 3203 Signatures of divergent antimalarial treatment responses in peripheral blood from infants and adults in Malawi Maurizio, P. L.; Fuseini, H.; Tegha, G.; Hosseinipour, M.; De Paris, K. 10.1101/564757 — immunology — Posted on 2019-03-01 3204 The DNA Methylome of Inflammatory Bowel Disease (IBD) reflects intrinsic and extrinsic factors in intestinal epithelial cells Agliata, I.; Fernandez-Jimenez, N.; Goldsmith, C.; Marie, J. C.; Bilbao, J. R.; Dante, R.; Hernandez-Vargas, H. 10.1101/565200 — genomics — Posted on 2019-03-01 3205 A nematode-specific gene underlies bleomycin-response variation in Caenorhabditis elegans Brady, S. C.; Zdraljevic, S.; Bisaga, K. W.; Tanny, R. E.; Cook, D. E.; Lee, D.; Wang, Y.; Andersen, E. C. 10.1101/565218 — genetics — Posted on 2019-03-01 3206 Evolutionary analyses unveil the molecular mechanism of fast inactivation in calcium-permeable TRP channels Flores-Aldama, L.; Vandewege, M.; Zavala, K.; Colenso, C.; Bustos, D.; Gonzalez, W.; Brauchi, S.; Opazo, J. C. 10.1101/564997 — evolutionary biology — Posted on 2019-03-01 3207 Consequences of recombination for the evolution of the mating type locus in Chlamydomonas reinhardtii Hasan, A. R.; Duggal, J. K.; Ness, R. W. 10.1101/565275 — evolutionary biology — Posted on 2019-03-01 3208 Top-down and bottom-up controls on soil carbon and nitrogen cycling with repeated burning across four ecosystems Pellegrini, A. F. A.; Hobbie, S. E.; Reich, P. B.; Jumpponen, A.; Brookshire, E. N. J.; Caprio, A. C.; Coetsee, C.; Jackson, R. B. 10.1101/565135 — ecology — Posted on 2019-03-01 3209 Supercharged Assembly: A Broad-Spectrum Mechanism of Action for Drugs that Undermine Controlled HIV-1 Viral Capsid Formation Pak, A. J.; Grime, J. M. A.; Yu, A.; Voth, G. A. 10.1101/565515 — biophysics — Posted on 2019-03-01 3210 Robust Determination of Protein Allosteric Signaling Pathways Luo, Y.; Botello-Smith, W. 10.1101/565457 — biophysics — Posted on 2019-03-01 3211 The size of the immune repertoire of bacteria Bradde, S.; Nourmohammad, A.; Goyal, S.; Balasubramanian, V. 10.1101/565366 — biophysics — Posted on 2019-03-01 3212 Mash Screen: High-throughput sequence containment estimation for genome discovery Ondov, B. D.; Starrett, G. J.; Sappington, A.; Kostic, A.; Koren, S.; Buck, C. B.; Phillippy, A. M. 10.1101/557314 — bioinformatics — Posted on 2019-03-01 3213 The DNA-binding protein HTa from Thermoplasma acidophilum is an archaeal histone analog Hocher, A.; Rojec, M.; Swadling, J. B.; Esin, A.; Warnecke, T. 10.1101/564930 — microbiology — Posted on 2019-03-01 3214 Shotgun proteomics analysis of nanoparticle-synthesising Desulfovibrio alaskensis in response to platinum and palladium Capeness, M.; Imrie, L.; Muhlbauer, L. F.; Le Bihan, T.; Horsfall, L. E. 10.1101/565036 — microbiology — Posted on 2019-03-01 3215 A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution Packer, J. S.; Zhu, Q.; Huynh, C.; Sivaramakrishnan, P.; Preston, E.; Dueck, H.; Stefanik, D.; Tan, K.; Trapnell, C.; Kim, J.; Waterston, R. H.; Murray, J. I. 10.1101/565549 — genomics — Posted on 2019-03-01 3216 New transcriptional circuit evolved by coding sequence changes in a master regulator followed by cis-regulatory changes in its target genes Britton, C. S.; Sorrells, T. R.; Johnson, A. D. 10.1101/565234 — evolutionary biology — Posted on 2019-03-01 3217 Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions Blasco, A.; Endres, M. G.; Sergeev, R. A.; Jonchhe, A.; Macaluso, M.; Narayan, R.; Natoli, T.; Paik, J. H.; Briney, B.; Wu, C.; Su, A. I.; Subramanian, A.; Lakhani, K. R. 10.1101/565481 — bioinformatics — Posted on 2019-03-01 3218 Avant-garde: An automated data-driven DIA data curation tool. Vaca Jacome, A. S.; Peckner, R.; Shulman, N.; Krug, K.; DeRuff, K. C.; Officer, A.; MacLean, B.; MacCoss, M. J.; Carr, S. A.; Jaffe, J. D. 10.1101/565523 — bioinformatics — Posted on 2019-03-01 3219 Body-map proto-organization in newborn macaques Arcaro, M.; Schade, P. F.; Livingstone, M. S. 10.1101/565390 — neuroscience — Posted on 2019-03-01 3220 Learning what is irrelevant or relevant: Expectations facilitate distractor inhibition and target facilitation through distinct neural mechanisms van Moorselaar, D.; Slagter, H. 10.1101/565069 — neuroscience — Posted on 2019-03-01 3221 Developmental Recovery of Impaired Multisensory Processing in Autism and the Cost of Switching Sensory Modality Crosse, M. J.; Foxe, J. J.; Molholm, S. 10.1101/565333 — neuroscience — Posted on 2019-03-01 3222 Zebrafish (Danio rerio) behavioral laterality predicts increased short-term avoidance memory but not stress-reactivity responses Dotto Fontana, B.; Cleal, M.; Clay, J.; Parker, M. O. 10.1101/565309 — animal behavior and cognition — Posted on 2019-03-01 3223 The Development of Optimally Responsive Plasmodium-specific CD73+CD80+ IgM+ Memory B cells Requires Intrinsic BCL6 expression but not CD4+ Tfh cells Pritchard, G. H.; Krishnamurty, A. T.; Netland, J.; Arroyo, E. N.; Takehara, K. K.; Pepper, M. 10.1101/564351 — immunology — Posted on 2019-03-01 3224 A single dose of dietary nitrate increases maximal muscle speed and power in healthy older men and women Coggan, A. R.; Hoffman, R. L.; Gray, D. A.; Moorthi, R. N.; Thomas, D. P.; Leibowitz, J. L.; Thies, D.; Peterson, L. R. 10.1101/564849 — physiology — Posted on 2019-03-01 3225 Short-term depression and long-term plasticity together tune sensitive range of synaptic plasticity Deperrois, N.; Graupner, M. 10.1101/565291 — neuroscience — Posted on 2019-03-01 3226 Effects of age, BMI and sex on the glial cell marker TSPO - a multicentre PBR28 HRRT PET study Tuisku, J.; Plaven-Sigray, P.; Gaiser, E. C.; Airas, L.; Al-Abdulrasul, H.; Bruck, A.; Carson, R. E.; Chen, M.-K.; Cosgrove, K. P.; Ekblad, L.; Esterlis, I.; Farde, L.; Forsberg, A.; Halldin, C.; Helin, S.; Kosek, E.; Lekander, M.; Lindgren, N.; Marjamaki, P.; Rissanen, E.; Sucksdorff, M.; Varrone, A.; HRRT [11C]PBR28 study group, ; Rinne, J.; Matuskey, D.; Cervenka, S. 10.1101/564831 — immunology — Posted on 2019-03-01 3227 Genetic inhibition of PCSK9, atherogenic lipoprotein concentrations, and calcific aortic valve stenosis Perrot, N.; Moschetta, D.; Boekholdt, M.; Valerio, V.; Martinsson, A.; Capoulade, R.; Mass, E.; Clavel, M.-A.; Wareham, N. J.; Dina, C.; Chen, H. Y.; Engert, J. C.; Thanassoulis, G.; Mathieu, P.; Bosse, Y.; Pibarot, P.; Smith, J. G.; Camera, M.; Theriault, S.; Poggio, P.; Arsenault, B. J. 10.1101/560458 — genetics — Posted on 2019-03-01 3228 A pleiotropic role for FGF signaling in mammary gland stromal fibroblasts Koledova, Z.; Sumbal, J. 10.1101/565267 — developmental biology — Posted on 2019-03-01 3229 A smooth muscle-like niche facilitates lung epithelial regeneration Moiseenko, A.; Vazquez-Armendariz, A. I.; Chu, X.; Guenther, S.; Lebrigand, K.; Kheirollahi, V.; Herold, S.; Braun, T.; Mari, B.; De Langhe, S.; Chen, C.; Li, X.; Seeger, W.; Zhang, J.-S.; Bellusci, S.; El Agha, E. 10.1101/565085 — developmental biology — Posted on 2019-03-01 3230 A novel growth factor-dependent thermogenic brown adipocyte cell line from defined precursor cells Kindler, D.; Sousa, I. S.; Schweizer, S.; Lerch, S.; Klingenspor, M.; Herzig, S.; Vegiopoulos, A. 10.1101/565168 — cell biology — Posted on 2019-03-01 3231 Pair-wise Comparison Analysis for Multiple Pool-sep: an efficient method identified anthocyanin biosynthesis genes in rice pericarp Yang, X.; Xia, X.; Zhang, Z.; Nong, B.; Zeng, Y.; Wu, Y.; Xiong, F.; Zhang, Y.; Liang, H.; Pan, Y.; Dai, G.; Deng, G.; Li, D. 10.1101/561258 — genomics — Posted on 2019-03-01 3232 'Candidatus Phytoplasma platensis', a novel taxon associated with daisy (Bellis perennis) virescence and related diseases in South America Fernandez, F. D.; Galdeano, E.; Conci, L. R. 10.1101/564807 — molecular biology — Posted on 2019-03-01 3233 An Oculometrics-based Biofeedback System to Impede Fatigue Development during Computer Work: a Proof-of-Concept Study Zargari Marandi, R.; Madeleine, P.; Vuillerme, N.; Omland, O.; Samani, A. 10.1101/563932 — physiology — Posted on 2019-03-01 3234 Estimation of neural network model parameters from local field potentials (LFPs) Skaar, J.-E. W.; Stasik, A. J.; Hagen, E.; Ness, T. V.; Einevoll, G. T. 10.1101/564765 — neuroscience — Posted on 2019-03-01 3235 Ancestral persistence of vestibulo-spinal reflexes in axial muscles in humans Guillaud, E.; Faure, C.; Doat, E.; Bouyer, L.; Guehl, D.; Cazalets, J.-R. 10.1101/564617 — neuroscience — Posted on 2019-03-01 3236 Active role of free RNA during the early phase of proteostasis stress Alriquet, M.; Martinez-Limon, A.; Hanspach, G.; Hengesbach, M.; Tartaglia, G. G.; Calloni, G.; Vabulas, R. M. 10.1101/564799 — cell biology — Posted on 2019-03-01 3237 Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin Auslander, N.; Heselmeyer-Haddad, K.; Patkar, S.; Hirsch, D.; Camps, J.; Brown, M.; Bronder, D.; Chen, W.-D.; Lokanga, R.; Wangsa, D.; Wangsa, D.; Hu, Y.; Lischka, A.; Braun, R.; Emons, G.; Ghadimi, B. M.; Gaedcke, J.; Grade, M.; Montagna, C.; Lazebnik, Y.; Difilippantonio, M. J.; Habermann, J. K.; Auer, G.; Ruppin, E.; ried, t. 10.1101/563858 — cancer biology — Posted on 2019-03-01 3238 Cue-induced effects on decision-making distinguish subjects with gambling disorder from healthy controls Genauck, A.; Andrejevic, M.; Brehm, K.; Matthis, C.; Heinz, A.; Weinreich, A.; Kathmann, N.; Romanczuk-Seiferth, N. 10.1101/564781 — neuroscience — Posted on 2019-03-01 3239 Salmonella genomic island 3 is an integrative and conjugative element and contributes to copper and arsenic resistance of Salmonella enterica Arai, N.; Sekizuka, T.; Tamamura, Y.; Kusumoto, M.; Hinenoya, A.; Yamasaki, S.; Iwata, T.; Watanabe-Yanai, A.; Kuroda, M.; Akiba, M. 10.1101/564534 — microbiology — Posted on 2019-03-01 3240 Spatial co-fragmentation pattern of cell-free DNA recapitulates in vivo chromatin organization and identifies tissues-of-origin Liu, Y.; Liu, T.-Y.; Weinberg, D. E.; White, B. W.; De La Torre, C. J.; Tan, C. L.; Schmitt, A. D.; Selvaraj, S.; Tran, V.; Laurent, L. C.; Cabel, L.; Bidard, F.-C.; Putcha, G.; Haque, I. S. 10.1101/564773 — genomics — Posted on 2019-03-01 3241 Transcriptome Profiling of Mouse Brain and Lung under Dip2A Regulation Using RNA-Sequencing Sah, R. K.; Anlan, Y.; Bah, F. B.; Adlat, S.; Bohio, A. A.; Oo, Z. M.; Wang, C.; Myint, M. Z. Z.; Bahadar, N.; Zhang, L.; Feng, X.; Zheng, Y. 10.1101/563916 — genetics — Posted on 2019-03-01 3242 Protein secondary structure determines the temporal relationship between folding and disulfide formation Robinson, P.; Kanemura, S.; Cao, X.; Bulleid, N. 10.1101/564740 — biochemistry — Posted on 2019-03-01 3243 Lifespan trajectories and relationships to memory of the macro- and microstructure of the anterior and posterior hippocampus - a longitudinal multi-modal imaging study Langnes, E.; Sneve, M. H.; Sederevicius, D.; Amlien, I. K.; Walhovd, K. B.; Fjell, A. M. 10.1101/564732 — neuroscience — Posted on 2019-03-01 3244 A Novel Ensemble-Based Machine Learning Algorithm To Predict The Conversion From Mild Cognitive Impairment To Alzheimer's Disease Using Socio-demographic Characteristics, Clinical Information And Neuropsychological Measures Grassi, M.; Rouleaux, N.; Caldirola, D.; Loewenstein, D.; Schruers, K.; Perna, G.; Dumontier, M. 10.1101/564716 — neuroscience — Posted on 2019-03-01 3245 Neph/Nephrin-like adhesion and tissue level pulling forces regulate cell intercalation during Drosophila retina development. Blackie, L.; Tozluoglu, M.; Trylinski, M.; Walther, R.; Mao, Y.; Schweisguth, F.; Pichaud, F. 10.1101/564708 — developmental biology — Posted on 2019-03-01 3246 Wnt activator FOXB2 drives prostate cancer neuroendocrine differentiation Moparthi, L.; Pizzolato, G.; Koch, S. 10.1101/564625 — cancer biology — Posted on 2019-03-01 3247 Association between development of early cortical activity on amplitude-integrated EEG and 5-years neurodevelopmental outcome in the preterm infant Feldmann, M.; Rousson, V.; Nguyen, T. D.; Bernet, V.; Hagmann, C.; Latal, B.; Natalucci, G. 10.1101/562488 — neuroscience — Posted on 2019-03-01 3248 Dopaminergic signalling is necessary, but not sufficient for cued fear memory destabilisation Lee, J. L. C.; Flavell, C. R. 10.1101/564674 — neuroscience — Posted on 2019-03-01 3249 High-throughput genotyping of a full voltage-gated sodium channel gene via genomic DNA using target capture sequencing and analytical pipeline MoNaS to discover novel insecticide resistance mutations Itokawa, K.; Yatsu, K.; Sekizuka, T.; Maekawa, Y.; Komagata, O.; Sugiura, M.; Sasaki, T.; Tomita, T.; Kuroda, M.; Sawabe, K.; Kasai, S. 10.1101/564609 — genetics — Posted on 2019-03-01 3250 Pluripotency factors regulate the onset of Hox cluster activation in the early embryo Lopez-Jimenez, E.; Sainz de Aja, J.; Badia-Careaga, C.; Barral, A.; Rollan, I.; Rouco, R.; Santos, E.; Tiana, M.; Victorino, J.; Sanchez-Iranzo, H.; Acemel, R. D.; Torroja, C.; Adan, J.; Andres-Leon, E.; Gomez-Skarmeta, J. L.; Giovinazzo, G.; Sanchez-Cabo, F.; Manzanares, M. 10.1101/564658 — developmental biology — Posted on 2019-03-01 3251 Nanotubes effectively deliver siRNA to intact plant cells and protect siRNA against nuclease degradation Demirer, G. S.; Zhang, H.; Goh, N. S.; Chang, R.; Landry, M. P. 10.1101/564427 — plant biology — Posted on 2019-03-01 3252 Emotion Modulation of the Body-Selective Areas in the Developing Brain Ross, P.; de Gelder, B.; Crabbe, F.; Grosbras, M.-H. 10.1101/564633 — neuroscience — Posted on 2019-03-01 3253 Snow is an important control of plant community functional composition Happonen, K.; Aalto, J.; Kemppinen, J.; Niittynen, P.; Virkkala, A.-M.; Luoto, M. 10.1101/564583 — ecology — Posted on 2019-03-01 3254 LonP1 Orchestrates UPRmt and UPRER and Mitochondrial Dynamics to Regulate Heart Function Lu, B.; Shangguan, F.; Huang, D.; Gong, S.; Shi, Y.; Song, Z.; Jia, L.; Xu, J.; Yan, C.; Chen, T.; Xu, M.; Li, Y.; Han, S.; Song, N.; Chen, P.; Wang, L.; Liu, Y.; Huang, X.; Suzuki, C. K.; Yang, Z.; Yang, G. 10.1101/564492 — cell biology — Posted on 2019-03-01 3255 siRNA containing a unique 5-nucleotide motif acts as a quencher of IFI16-mediated innate immune response Sui, H.; Yang, J.; Hu, X.; Imamichi, T.; Chen, Q. 10.1101/564872 — immunology — Posted on 2019-03-01 3256 The Microbial Metagenome and Tissue Composition in Mice with Microbiome-Induced Reductions in Bone Strength Guss, J. D.; Taylor, E.; Rouse, Z.; Roubert, S.; Higgins, C. H.; Thomas, C. J.; Baker, S.; Vashishth, D.; Donnelly, E.; Shea, M. K.; Booth, S. L.; Bicalho, R. L.; Hernandez, C. 10.1101/562058 — bioengineering — Posted on 2019-03-01 3257 In vivo study of gene expression with an enhanced dual-color fluorescent transcriptional timer He, L.; Perrimon, N.; Binari, R.; Huang, J.; Falo, J. 10.1101/564690 — developmental biology — Posted on 2019-03-01 3258 Predicting nucleation sites in chemotaxing Dictyostelium discoideum Asante-Asamani, E. O.; Rawal, D.; Santiago, Z.; Brazill, D.; Loustau, J. 10.1101/564963 — cell biology — Posted on 2019-03-01 3259 Diflunisal targets the HMGB1/CXCL12 heterocomplex and blocks immune cell recruitment De Leo, F.; Quilici, G.; Tirone, M.; Mannella, V.; De Marchis, F.; Preti, A.; Gori, A.; Casalgrandi, M.; Mezzapelle, R.; Bianchi, M.; Musco, G. 10.1101/563890 — biochemistry — Posted on 2019-03-01 3260 Mannitol ingestion causes concentration-dependent, sex-specific mortality in adults of the fruit fly (Drosophila melanogaster). Fiocca, K.; Barrett, M.; Waddell, E. A.; McNair, C.; O'Donnell, S.; Marenda, D. R. 10.1101/564898 — zoology — Posted on 2019-03-01 3261 Operating regimes in a single enzymatic cascade at ensemble-level Parundekar, A.; Kalantre, G.; Khadpekar, A.; Viswanathan, G. A. 10.1101/564922 — systems biology — Posted on 2019-03-01 3262 Excitatory and inhibitory subnetworks are equally selective during decision-making and emerge simultaneously during learning Najafi, F.; Elsayed, G. F.; Cao, R.; Pnevmatikakis, E.; Latham, P. E.; Cunningham, J.; Churchland, A. K. 10.1101/354340 — neuroscience — Posted on 2019-03-01 3263 Diversity patterns in parasite populations capable forpersistence and reinfection with a view towards the humancytomegalovirus Pokalyuk, C.; Goerzer, I. 10.1101/512970 — evolutionary biology — Posted on 2019-03-01 3264 Deconvolving multiplexed protease signatures with substrate reduction and activity clustering Zhuang, Q.; Holt, B. A.; Kwong, G. A.; Qiu, P. 10.1101/564906 — bioengineering — Posted on 2019-03-01 3265 Effective Public Apologies Kim, H.; Kralik, J. D.; Yun, K.; Chung, Y.-a.; Jeong, J. 10.1101/564880 — neuroscience — Posted on 2019-03-01 3266 Antimicrobial susceptibility and serotype distribution of Streptococcus agalactiae recto-vaginal colonizing isolates from pregnant women at a tertiary hospital in Pretoria, South Africa: an observational descriptive study letter Said, M.; Dangor, Y.; Mbelle, N.; Madhi, S.; Kwatra, G.; Ismail, F. 10.1101/564856 — microbiology — Posted on 2019-03-01 3267 The role of structural pleiotropy and regulatory evolution in the retention of heteromers of paralogs Marchant, A.; Cisneros, A.; Dube, A.; Gagnon-Arsenault, I.; Ascencio, D.; Jain, H.; Aube, S.; Eberlein, C.; Evans-Yamamoto, D.; Yachie, N.; Landry, C. 10.1101/564401 — evolutionary biology — Posted on 2019-03-01 3268 The Development of Optimally Responsive Plasmodium-specific CD73+CD80+ IgM+ Memory B cells Requires Intrinsic BCL6 expression butnot CD4+ Tfh cells Pritchard, G. H.; Pepper, M.; Krishnamurty, A. T.; Netland, J.; Arroyo, E. N.; Takehara, K. K. 10.1101/564351 — immunology — Posted on 2019-03-01 3269 The alternative reality of plant mitochondrial DNA Kozik, A.; Rowan, B.; Lavelle, D.; Berke, L.; Schranz, M. E.; Michelmore, R. W.; Christensen, A. C. 10.1101/564278 — genomics — Posted on 2019-03-01 3270 RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression. Marshall, A.; Roes, M.; Passos, D. T.; DeWeerd, M.; Chaikovsky, A.; Sage, J.; Howlett, C.; Dick, F. A. 10.1101/564567 — cancer biology — Posted on 2019-03-01 3271 Glycosylation of Zika Virus Is Important in Host-Virus Interaction and Pathogenesis Routhu, N. K.; Lehoux, S. D.; Rouse, E. A.; Bidokhti, M. R. M.; Giron, L. B.; Anzurez, A.; Reid, S. P.; Abdel-Mohsen, M.; Cummings, R. D.; Byrareddy, S. N. 10.1101/564542 — biochemistry — Posted on 2019-03-01 3272 Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies Gurbatri, C.; Coker, C.; Hinchliffe, T. E.; Lia, I.; Castro, S.; Treuting, P. M.; Arpaia, N.; Danino, T. 10.1101/562785 — synthetic biology — Posted on 2019-03-01 3273 mTORC1 IN THE ORBITOFRONTAL CORTEX PROMOTES HABITUAL ALCOHOL SEEKING Morisot, N.; Berger, A.; Phamluong, K.; Laguesse, S.; Moffat, J.; Ron, D. 10.1101/564310 — neuroscience — Posted on 2019-03-01 3274 Decreasing Serine Levels During Growth Transition Triggers Biofilm Formation in Bacillus subtilis Greenwich, J.; Reverdy, A.; Gozzi, K.; Di Cecco, G.; Tashjian, T. F.; Godoy-Carter, V.; Chai, Y. 10.1101/564526 — microbiology — Posted on 2019-03-01 3275 Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology Mesman, A. W.; Soto, M.; Coit, J.; Calderon, R.; Aliaga, J.; Pollock, N. R.; Mendoza, M.; Mestanza, F. M.; Mendoza, C. J.; Murray, M. B.; Lecca, L.; Holmberg, R.; Franke, M. F. 10.1101/564088 — microbiology — Posted on 2019-03-01 3276 Streamlined low-input transcriptomics through EASY-RNAseq Zhou, Y.; Xu, H.; Wu, H.; Yu, H.; Zhou, P.; Qiu, X.; Zheng, Z.; Chen, Q.; Xu, F.; Li, G.; Zhou, J.; Cheng, G.; He, W.; Zou, L.; Wan, Y. 10.1101/564468 — genomics — Posted on 2019-03-01 3277 Pluripotency and the origin of animal multicellularity Sogabe, S.; Hatleberg, W.; Kocot, K.; Say, T.; Stoupin, D.; Roper, K.; Fernandez-Valverde, S.; Degnan, S.; Degnan, B. 10.1101/564518 — evolutionary biology — Posted on 2019-03-01 3278 Comparing Time Series Transcriptome Data Between Plants Using A Network Module Finding Algorithm Lee, J.; Heath, L.; Grene, R.; Li, S. 10.1101/564286 — bioinformatics — Posted on 2019-03-01 3279 A molecular model for self-assembly of synaptonemal complex protein SYCE3 Dunne, O. M.; Davies, O. R. 10.1101/564237 — biochemistry — Posted on 2019-03-01 3280 Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification Thomas, S. E.; Whitehouse, A. J.; Brown, K.; Belardinelli, J. M.; Lahiri, R.; Libardo, M. D. J.; Gupta, P.; Malhotra, S.; Boshoff, H. I. M.; Jackson, M.; Abell, C.; Coyne, A. G.; Blundell, T. L.; Floto, R. A.; Mendes, V. 10.1101/564013 — biochemistry — Posted on 2019-03-01 3281 Multi-omics Integrative Analysis of Acute and Relapsing Malaria in a Non-Human Primate Model of P. vivax infection Tang, Y.; Joyner, C. J.; Cordy, R. J.; Malaria Host-Pathogen Interaction Center (MaHPIC), ; Galinski, M. R.; Lamb, T. J.; Styczynski, M. P. 10.1101/564195 — systems biology — Posted on 2019-03-01 3282 Programmable bacteria induce durable tumor regression and systemic antitumor immunity Chowdhury, S.; Hinchliffe, T. E.; Castro, S.; Coker, C.; Arpaia, N.; Danino, T. 10.1101/561159 — synthetic biology — Posted on 2019-03-01 3283 Cognitive capacity limits are remediated by practice-induced plasticity in a striatal-cortical network Garner, K.; Garrido, M. I.; Dux, P. E. 10.1101/564450 — neuroscience — Posted on 2019-03-01 3284 Dynamic compression and expansion in a classifying recurrent network Farrell, M. S.; Recanatesi, S.; Lajoie, G.; Shea-Brown, E. 10.1101/564476 — neuroscience — Posted on 2019-03-01 3285 Return of an apex predator to a suburban preserve triggers a rapid trophic cascade Leempoel, K.; Meyer, J. M.; Hebert, T.; Nova, N.; Hadly, E. A. 10.1101/564294 — ecology — Posted on 2019-03-01 3286 Principles and characteristics of biological assemblies in experimentally determined protein structures Xu, Q.; Dunbrack, R. 10.1101/564385 — bioinformatics — Posted on 2019-03-01 3287 Longshot: accurate variant calling in diploid genomes using single-molecule long read sequencing Edge, P.; Bansal, V. 10.1101/564443 — bioinformatics — Posted on 2019-03-01 3288 Dynamic alterations of retinal EphA5 expression in retinocollicular map plasticity Cheng, Q.; Graves, M. D.; Pallas, S. L. 10.1101/433904 — neuroscience — Posted on 2019-03-01 3289 Dinucleoside polyphosphates act as 5'-RNA caps in Escherichia coli Hudecek, O.; Benoni, R.; Culka, M.; Hubalek, M.; Rulisek, L.; Cvacka, J.; Cahova, H. 10.1101/563817 — molecular biology — Posted on 2019-03-01 3290 Serodiagnostic potential of synthetic peptides derived from African swine fever virus putative protein pCP312R Ochwo, S.; Atuhaire, D. K.; Afayoa, M.; Kisseka, M.; Magambo, P. K.; Ndekezi, C.; Okuni, J. B.; Olaho-Mukani, W.; Ojok, L. 10.1101/512772 — immunology — Posted on 2019-03-01 3291 Tracking genetic invasions: genome-wide SNPs reveal the source of pyrethroid-resistant Aedes aegypti (yellow fever mosquito) incursions at international ports Schmidt, T.; van Rooyen, A. R.; Chung, J.; Endersby-Harshman, N. M.; Griffin, P. C.; Sly, A.; Hoffmann, A. A.; Weeks, A. R. 10.1101/490714 — genomics — Posted on 2019-03-01 3292 UDCT: Unsupervised data to content transformation with histogram-matching cycle-consistent generative adversarial networks Ihle, S. J.; Reichmuth, A. M.; Girardin, S.; Han, H.; Stauffer, F.; Bonnin, A.; Stampanoni, M. F. M.; Voros, J.; Forro, C. 10.1101/563734 — bioengineering — Posted on 2019-03-01